WorldWideScience

Sample records for hon facs hon

  1. Web page translating software program The Hon-yaku; Hon'yaku software 'The hon'yaku

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    A translating software program The Hon-yaku (the translator) Internet V4.0 has been developed, which provides an optimum means to help those who have to perform English-Japanese and Japanese-English translation on the Internet in collecting information from abroad, e-mailing to other countries, and chatting (exchanging of messages or dialogues) with friends overseas. When the Shortcut Read function is used, the user is instantly provided with the gist of the page on the screen even if it is full of long sentences. The program, furthermore, is equipped with a function of translating documents prepared using the state-of-the-art XML (eXtensible Markup Language) and PDF (Portable Document Format) technologies. Another translation software program The Hon-yaku Office V2.0 has also been developed, which adds a translating function to Microsoft(reg sign) Office 2000. Using this program, translation is completed upon clicking on the translation button on a Word, Excel, or Power Point(reg sign) screen. A template etc. are also provided, which simplifies the preparation of business letters in English. (translated by NEDO)

  2. Knudsen cell vaporization of rare earth nitrides: enthalpy of vaporization of HoN098

    International Nuclear Information System (INIS)

    Brown, R.C.; Clark, N.J.

    1975-01-01

    The enthalpy of vaporization of HoN 0 . 98 was measured by the weight-loss Knudsen cell technique using Motzfeldt-Whitman extrapolations to zero orifice area. A third-law enthalpy of vaporization of HoN 0 . 98 of 155.9 +- 5 kcal mole -1 was obtained compared to a second-law value of 162.0 +- 5 kcal mole -1 . Similar measurements on the nitrides of samarium, erbium, and ytterbium gave third-law enthalpies of vaporization of 126.8 +-- 5 kcal mole -1 ; 159.6 +- 5 kcal mole -1 , and 121.0 +- 5 kcal mole -1 , respectively. 7 tables

  3. An evaluation of the quality of Turkish community pharmacy web sites concerning HON principles.

    Science.gov (United States)

    Yegenoglu, Selen; Sozen, Bilge; Aslan, Dilek; Calgan, Zeynep; Cagirci, Simge

    2008-05-01

    The objective of this study was to find all the existing Web sites of Turkish community pharmacies and evaluate their "quality" in terms of Health on the Net (HON) Code of conduct principles. Multiple Internet search engines were used (google.com, yahoo.com, altavista.com, msn.com). While searching on the Internet, "eczane (pharmacy)" and "eczanesi (pharmacy of)" key words were used. The Internet search lasted for 2 months starting from March 1, 2007 until May 1, 2007. SPSS ver. 11.5 statistical program (SPSS, Inc., Chicago, IL) was used for data entry and analysis. At the end of the Internet search via all the indicated search engines, a total of 203 (all different from each other) community pharmacy Web sites were determined; of these, 14 were under construction and 6 were not accessible. As a result, 183 community pharmacy Web sites were included in the study. All of the Web sites could be accessed (100%). However, the availability of some characteristics of the pharmacies were quite poor. None of the pharmacies met all of the HON principles. Only 11 Web sites were appropriate in terms of complementarity (6.0%). Confidentiality criteria was met by only 14 pharmacies (7.7%). Nine pharmacies (4.9%) completed the "attribution" criteria. Among 183 pharmacy Web sites, the most met HON principle was the "transparency of authorship" (69 pharmacy Web sites; 37.7%). Because of the results of our study, the Turkish Pharmacists Association can take a pioneer role to apply some principles such as HON code of conduct in order to increase the quality of Turkish community pharmacists' Web sites.

  4. HON label and DISCERN as content quality indicators of health-related websites.

    Science.gov (United States)

    Khazaal, Yasser; Chatton, Anne; Zullino, Daniele; Khan, Riaz

    2012-03-01

    Content quality indicators are warranted in order to help patients and consumers to judge the content quality of health-related on-line information. The aim of the present study is to evaluate web-based information on health topics and to assess particular content quality indicators like HON (Health on the Net) and DISCERN. The present study is based on the analysis of data issued from six previous studies which assessed with a standardized tool the general and content quality (evidence-based health information) of health-related websites. Keywords related to Social phobia, bipolar disorders, pathological gambling as well as cannabis, alcohol and cocaine addiction were entered into popular World Wide Web search engines. Websites were assessed with a standardized proforma designed to rate sites on the basis of accountability, presentation, interactivity, readability and content quality (evidence-based information). "Health on the Net" (HON) quality label, and DISCERN scale scores were used to verify their efficiency as quality indicators. Of 874 websites identified, 388 were included. Despite an observed association with higher content quality scores, the HON label fails to predict good content quality websites when used in a multiple regression. Sensibility and specificity of a DISCERN score >40 in the detection of good content quality websites were, respectively, 0.45 and 0.96. The DISCERN is a potential quality indicator with a relatively high specificity. Further developments in this domain are warranted in order to facilitate the identification of high-quality information on the web by patients.

  5. La Justice et la Vengeance divine poursuivant le Crime. Pierre-Paul Prud’hon a emblematická tradice

    Czech Academy of Sciences Publication Activity Database

    Konečný, Lubomír

    2014-01-01

    Roč. 63, 1/2 (2014), s. 86-93 ISSN 1211-7390 Institutional support: RVO:68378033 Keywords : Pierre-Paul Prud’hon * Nicolas Frochot * Marin Le Roy de Gomberville * Otto van Veen Subject RIV: AL - Art, Architecture, Cultural Heritage

  6. [Teaching, research, and extension service: botanist Honório da Costa Monteiro Filho].

    Science.gov (United States)

    Bovini, Massimo G; Peixoto, Ariane Luna

    2012-12-01

    The article revisits the work of Honório da Costa Monteiro Filho, highlighting his contribution to the study of economic botany and the taxonomy of Brazilian Malvaceae. Many of his seventy articles, are still cited. Yet little is known about his important role in educating agronomists involved with Brazilian flora and the creation of the Botanical Society of Brazil. These topics are discussed in the article, along with his work on a project to reform the teaching of agronomy in Brazil. The entire works of Monteiro Filho, archival documents, his correspondence with other scientists, and his observations on plant labels in herbaria were researched; interviews were also conducted with people with ties to him.

  7. UST1/435: HON's Fourth Survey on the Usage of the Internet for Medical and Health Internet Purposes

    OpenAIRE

    Boyer, C; Baujard, V; Nater, T; Scherrer, JR; Appel, R

    1999-01-01

    Introduction To remain competitive, the providers of medical and health-related information must continually adapt their Web sites to new market demands and trends. Successful adaptation depends, among other things, on understanding users' needs. The Health on the Net Foundation (HON) has been conducting regular surveys of user-traffic since 1997. The fourth and latest in the series, conducted through the months of March and April, 1999, obtained 4,437 responses, compared to 1,863 responses o...

  8. Drivers of coastal shoreline change: case study of hon dat coast, Kien Giang, Vietnam.

    Science.gov (United States)

    Nguyen, Hai-Hoa; McAlpine, Clive; Pullar, David; Leisz, Stephen Joseph; Galina, Gramotnev

    2015-05-01

    Coastal shorelines are naturally dynamic, shifting in response to coastal geomorphological processes. Globally, land use change associated with coastal urban development and growing human population pressures is accelerating coastal shoreline change. In southern Vietnam, coastal erosion currently is posing considerable risks to shoreline land use and coastal inhabitants. The aim of this paper is to quantify historical shoreline changes along the Hon Dat coast between 1995 and 2009, and to document the relationships between coastal mangrove composition, width and density, and rates of shoreline change. The generalized linear mixed-effects models were used to quantify the major biophysical and land-use factors influencing shoreline change rates. Most significant drivers of the rates of change are cutting of mangroves, the dominant mangrove genus, changes in adjacent shoreline land use, changes of shoreline land cover, and width of fringing mangroves. We suggest that a possible and inexpensive strategy for robust mangrove shoreline defense is direct mangrove planting to promote mangrove density with the presence of breakwater structures. In the shorter term, construction of coastal barriers such as fence-structured melaleuca poles in combination with mangrove restoration schemes could help retain coastal sediments and increase the elevation of the accretion zone, thereby helping to stabilize eroding fringe shorelines. It also is recommended that implementation of a system of payments for mangrove ecosystem services and the stronger regulation of mangrove cutting and unsustainable land-use change to strengthen the effectiveness of mangrove conservation programs and coastal land-use management.

  9. Drivers of Coastal Shoreline Change: Case Study of Hon Dat Coast, Kien Giang, Vietnam

    Science.gov (United States)

    Nguyen, Hai-Hoa; McAlpine, Clive; Pullar, David; Leisz, Stephen Joseph; Galina, Gramotnev

    2015-05-01

    Coastal shorelines are naturally dynamic, shifting in response to coastal geomorphological processes. Globally, land use change associated with coastal urban development and growing human population pressures is accelerating coastal shoreline change. In southern Vietnam, coastal erosion currently is posing considerable risks to shoreline land use and coastal inhabitants. The aim of this paper is to quantify historical shoreline changes along the Hon Dat coast between 1995 and 2009, and to document the relationships between coastal mangrove composition, width and density, and rates of shoreline change. The generalized linear mixed-effects models were used to quantify the major biophysical and land-use factors influencing shoreline change rates. Most significant drivers of the rates of change are cutting of mangroves, the dominant mangrove genus, changes in adjacent shoreline land use, changes of shoreline land cover, and width of fringing mangroves. We suggest that a possible and inexpensive strategy for robust mangrove shoreline defense is direct mangrove planting to promote mangrove density with the presence of breakwater structures. In the shorter term, construction of coastal barriers such as fence-structured melaleuca poles in combination with mangrove restoration schemes could help retain coastal sediments and increase the elevation of the accretion zone, thereby helping to stabilize eroding fringe shorelines. It also is recommended that implementation of a system of payments for mangrove ecosystem services and the stronger regulation of mangrove cutting and unsustainable land-use change to strengthen the effectiveness of mangrove conservation programs and coastal land-use management.

  10. Hon-yaku: a biology-driven Bayesian methodology for identifying translation initiation sites in prokaryotes

    Directory of Open Access Journals (Sweden)

    de Hoon Michiel JL

    2007-02-01

    Full Text Available Abstract Background Computational prediction methods are currently used to identify genes in prokaryote genomes. However, identification of the correct translation initiation sites remains a difficult task. Accurate translation initiation sites (TISs are important not only for the annotation of unknown proteins but also for the prediction of operons, promoters, and small non-coding RNA genes, as this typically makes use of the intergenic distance. A further problem is that most existing methods are optimized for Escherichia coli data sets; applying these methods to newly sequenced bacterial genomes may not result in an equivalent level of accuracy. Results Based on a biological representation of the translation process, we applied Bayesian statistics to create a score function for predicting translation initiation sites. In contrast to existing programs, our combination of methods uses supervised learning to optimally use the set of known translation initiation sites. We combined the Ribosome Binding Site (RBS sequence, the distance between the translation initiation site and the RBS sequence, the base composition of the start codon, the nucleotide composition (A-rich sequences following start codons, and the expected distribution of the protein length in a Bayesian scoring function. To further increase the prediction accuracy, we also took into account the operon orientation. The outcome of the procedure achieved a prediction accuracy of 93.2% in 858 E. coli genes from the EcoGene data set and 92.7% accuracy in a data set of 1243 Bacillus subtilis 'non-y' genes. We confirmed the performance in the GC-rich Gamma-Proteobacteria Herminiimonas arsenicoxydans, Pseudomonas aeruginosa, and Burkholderia pseudomallei K96243. Conclusion Hon-yaku, being based on a careful choice of elements important in translation, improved the prediction accuracy in B. subtilis data sets and other bacteria except for E. coli. We believe that most remaining

  11. Rational design, synthesis, and pharmacological properties of new 1,8-naphthyridin-2(1H)-on-3-carboxamide derivatives as highly selective cannabinoid-2 receptor agonists

    DEFF Research Database (Denmark)

    Manera, Clementina; Saccomanni, Giuseppe; Adinolfi, Barbara

    2009-01-01

    The CB(2) receptor activation can be exploited for the treatment of diseases such as chronic pain and tumors of immune origin, devoid of psychotropic activity. On the basis of our already reported 1,8-naphthyridin-4(1H)-on-3-carboxamide derivatives, new 1,8-naphthyridin-2(1H)-on-3-carboxamide......-dependent decrease of cell viability. The obtained results suggest that 1,8-naphthyridin-2(1H)-on-3-carboxamides represent a new scaffold very suitable for the development of new promising CB(2) agonists....... derivatives were designed, synthesized, and tested for their affinities toward the human CB(1) and CB(2) cannabinoid receptors. Some of the reported compounds showed a subnanomolar CB(2) affinity with a CB(1)/CB(2) selectivity ratio greater than 200 (compounds 6, 12, cis-12, 13, and cis-13). Further studies...

  12. Ensino, pesquisa e extensão: o botânico Honório da Costa Monteiro Filho Teaching, research, and extension service: botanist Honório da Costa Monteiro Filho

    Directory of Open Access Journals (Sweden)

    Massimo G. Bovini

    2012-12-01

    Full Text Available O artigo revisita a obra de Honório da Costa Monteiro Filho e enfatiza sua contribuição valiosa para o estudo da botânica econômica e a taxonomia das Malvaceae brasileiras. Muitos de seus cerca de setenta artigos ainda hoje são citados, mas pouco se sabe sobre seu importante papel na formação de agrônomos envolvidos com a caracterização da flora brasileira e na criação da Sociedade Botânica do Brasil, bem como sua atuação em projeto de reforma do ensino agronômico no país. Foram pesquisados a obra completa de Monteiro Filho, documentos em arquivos, sua correspondência e suas observações em etiquetas de plantas em herbários, e realizadas entrevistas com pessoas de sua convivência.The article revisits the work of Honório da Costa Monteiro Filho, highlighting his contribution to the study of economic botany and the taxonomy of Brazilian Malvaceae. Many of his seventy articles, are still cited. Yet little is known about his important role in educating agronomists involved with Brazilian flora and the creation of the Botanical Society of Brazil. These topics are discussed in the article, along with his work on a project to reform the teaching of agronomy in Brazil. The entire works of Monteiro Filho, archival documents, his correspondence with other scientists, and his observations on plant labels in herbaria were researched; interviews were also conducted with people with ties to him.

  13. Systematic notes on Asian birds. 46. ‘A Catalogue of the Birds in the Museum of the Hon. East-India Company’ by Horsfield & Moore

    NARCIS (Netherlands)

    Dickinson, E.C.

    2004-01-01

    Ornithological literature has been extremely inconsistent in assigning authorship for the new names proposed in ‘A Catalogue of the Birds in The Museum of the Hon. East-India Company’ by Horsfield & Moore, or by Moore in parallel to it. The corrected dates of separate publications by Moore and the

  14. A New Species of Cleisostoma (Orchidaceae from the Hon Ba Nature Reserve in Vietnam: A Multidisciplinary Assessment.

    Directory of Open Access Journals (Sweden)

    Jan Ponert

    Full Text Available A new species, Cleisostoma yersinii J. Ponert & Vuong, is described and illustrated based on the material collected in the Hon Ba Nature Reserve in southern Vietnam. In addition to conventional (macromorphological examination we comparatively investigated root and leaf anatomy (using light and fluorescent microscopy, assessed nectar characteristics (using HPLC analysis, determined nuclear genome size (using DNA flow cytometry and reconstructed phylogenetic relationships (using nrITS sequences. Cleisostoma yersinii differs from its putative closest relative C. birmanicum in wider and shorter leaves, larger flowers, distinct lip with S-shaped tip of the mid-lobe, and a shallow spur with two large nectar sacks separated by prominent calli and septum. Nectar is sucrose-dominant and very rich in sugars. Stomata are developed on both sides of the leaf and have prominent hyperstomatal chambers and substomatal cavities. Roots with well-developed exodermis and tracheoidal idioblasts are covered by a two-layer Vanda-type velamen. Chloroplasts occur not only in the cortex but are also abundant in the stele. Mean 1C-value was estimated to 2.57 pg DNA. An updated identification key is provided for SE Asian sections and all Vietnamese species of Cleisostoma.

  15. First-principles calculations of electronic, magnetic and optical properties of HoN doped with TM (Ti, V, Cr, Mn, Co and Ni)

    Science.gov (United States)

    Rouchdi, M.; Salmani, E.; Dehmani, M.; Ez-Zahraouy, H.; Hassanain, N.; Benyoussef, A.; Mzerd, A.

    2018-02-01

    Using the first-principles calculations within the Korringa-Kohn-Rostoker (KKR) method combined with the coherent potential approximation (CPA), the structural, optical and magnetic properties of rare-earth nitride Ho0.95TM0.05N doped with transition metal (TM) atoms (Ti, V, Cr, Mn, Co and Ni) are investigated as a function the generalized gradient approximation and self-interaction correction (GGA-SIC) approximation. The optical properties are studied in detail by using ab-initio calculations. Using GGA-SIC we have showed that the bandgap value is in good agreement with the experimental value. Using GGA-SIC approximation for HoN, we have obtained a bandgap of 0.9 eV. Some of the dilute magnetic semiconductors (DMS) like Ho0.95TM0.05N under study exhibit a half-metallic behavior, which makes them suitable for spintronic applications. Moreover, the optical absorption spectra confirm the ferromagnetic stability based on the charge state of magnetic impurities.

  16. 14th March 2011 - Australian Senator the Hon. K. Carr Minister for Innovation, Industry, Science and Research in the ATLAS Visitor Centre with Collaboration Spokesperson F. Gianotti,visiting the SM18 area with G. De Rijk,the Computing centre with Department Head F. Hemmer, signing the guest book with Director-General R. Heuer with Head of International relations F. Pauss

    CERN Multimedia

    Jean-claude Gadmer

    2011-01-01

    14th March 2011 - Australian Senator the Hon. K. Carr Minister for Innovation, Industry, Science and Research in the ATLAS Visitor Centre with Collaboration Spokesperson F. Gianotti,visiting the SM18 area with G. De Rijk,the Computing centre with Department Head F. Hemmer, signing the guest book with Director-General R. Heuer with Head of International relations F. Pauss

  17. 8 April 2013 - Indian Hon'ble Minister for Ministry of Science & Technology and Ministry of Earth Sciences Shri Sudini Jaipal Reddy in the LHC tunnel with K. Foraz, visiting the CMS cavern with Technical Coordinator A. Ball and Former Spokesperson T. Virdee, signing the guest book with Director-General R. Heuer.

    CERN Multimedia

    Samuel Morier-Genoud

    2013-01-01

    8 April 2013 - Indian Hon'ble Minister for Ministry of Science & Technology and Ministry of Earth Sciences Shri Sudini Jaipal Reddy in the LHC tunnel with K. Foraz, visiting the CMS cavern with Technical Coordinator A. Ball and Former Spokesperson T. Virdee, signing the guest book with Director-General R. Heuer.

  18. 8 February 2017 - Sri Lanka Hon. Minister of Science, Technology and Research A. D. S. Premajayantha signing the International Cooperation Agreement concerning Scientific and Technical Cooperation in High-Energy Physics 2017 with CERN Director for International Relations C. Warakaulle.

    CERN Multimedia

    Brice, Maximilien

    2017-01-01

    Were present: Hon. A. D. Susil Premajayantha, Minister of Science, Technology and Research, Democratic Socialist Republic of Sri Lanka; H.E. Mr Ravinatha Aryasinha, Ambassador, Permanent Representative of Sri Lanka to the UN in Geneva; Mrs Samantha Jayasuriya, Deputy Permanent Representative, Permanent Mission of Sri Lanka to the UN in Geneva; Ms Shashika Somaratne, Counsellor, Permanent Mission of Sri Lanka to the UN in Geneva; Mr Gihan Indragupta, Member of Sri Lanka Foreign service and Head of the G15 Secretariat; Ms Dilini Gunasekera, Second Secretary, Permanent Mission of Sri Lanka to the UN in Geneva; Mr Prageeth Herath , Supporting staff, Permanent Mission of Sri Lanka. CERN: Mr Andrzej Charkiewicz, CMS Ressources Manager; Ms Sofia Intoudi, Legal Officer; Dr Rüdiger Voss, Senior Adviser, International Relations; Ms Charlotte Warakaulle, Director for International Relations

  19. An investigation onto the molecular structure of 5-chloro-3-(2-(4-ethylpiperazine-1-il)-2-oxoethyl)benzo[d]thiazole-2(3H)-on drug molecule before and after atmospheric pressure plasma treatment

    Science.gov (United States)

    Tanışlı, Murat; Taşal, Erol; Şahin, Neslihan; Dikmen, Gökhan

    2018-05-01

    The spectra of molecular structure for the 5-chloro-3-(2-(4-ethylpiperazine-1-il)-2-oxoethyl)benzo[d]thiazole-2(3H)-on drug molecule (abbreviated as 5KEB) before and after the atmospheric pressure plasma treatments (APPTs) of neon (Ne) and argon (Ar) were investigated. The Fourier transform infrared (FT-IR), ultraviolet visible (UV-Vis) spectra and NMR measurements of the 5KEB drug molecule dissolved in toluene and ethanol solvents were recorded and examined for liquid phases. Then FT-IR, UV-Vis spectra and NMR measurements were analysed. It is seen that some bonds of 5KEB molecule were decomposed. There were also unobserved vibrational modes. After the Ne plasma at the atmospheric pressure applied to 5KEB drug molecule dissolved in toluene, the bonds as 9Ssbnd 8C; 9Ssbnd 8C = 10 O, 8Csbnd 7N, 7Nsbnd 8C = 10O were vanished, and then the new bonds of the 7N = 8C, 7N = 8C = 10 O, 9Ssbnd 5Csbnd 4Csbnd 7N = 8C = 10O were observed. New photoproducts may be defined as the stretching peaks, stretching vibrational modes for 5KEB drug molecule in liquid phase prepared with ethanol and toluene solvents after APPT. Also, after Ar plasma at atmospheric pressure applied here, the 9Ssbnd 8C bond of the 5KEB drug molecule dissolved in toluene was broken. The isomerization process in UV-Vis was defined by π-π* and n-π* electronic transitions. According to NMR results, protons of pyridine ring, protons of CH2 group bonded to carbonyl group and protons of CH3 group more affected than other protons from Ar and Ne APPTs and these protons were eliminated by Ar and Ne APPTs.

  20. “Behandl dig selv med honning"

    DEFF Research Database (Denmark)

    Mejrup, Kristian; Bjerring-Nielsen, Mattias

    2015-01-01

    Abstract: This article has a twofold purpose: to investigate the symbolic richness and abundant sweetness of honey and to employ ‘honey treatment’ as a strategy for reading the honeycombapocalypse comprised in the Jewish legend of Joseph and Aseneth. This text tells of Aseneth’s encounter with a ...... entirely perturbed and paralysed. In fact, her free speech and wits remain as if protected by a honeysweetened agency. The article emphasizes the necessity of a ‘conversion’ by the reader enabling him to grasp the sublime potential of the aesthetics of sweetness....

  1. Architecture, landscape architecture and interior- Hons B 2009

    CSIR Research Space (South Africa)

    Osman, A

    2010-03-01

    Full Text Available will be as follows: 1. History of Urban Form 2. Urban Renewal and Reactions 3. Urban Order, Security and Power 4. Colonial Impact on Urban From 5. Memory and Conservation 6. Considering the Public and Private Realm 7. Housing and Urban Form ? Type, Poetics 8....e. ?interior design? / ?inte- rior architecture?). Interior design is the reaction to ?found? space and follows three modes of produc- tion: installation, insertion and intervention. Archi- tectural theory pertinent to the discipline?s ontology...

  2. Transparency and Quality of Health Apps: The HON Approach.

    Science.gov (United States)

    Ranasinghe, Mayoni; Cabrera, Aude; Postel-Vinay, Nicolas; Boyer, Célia

    2018-01-01

    We are well into the 21st century and the Internet has been around long enough that there are adults who have not known a world without this wonderful tool. And just as time has gone since the beginnings of the Internet, so too has it developed, probably above and beyond the wildest dreams of its founders. These developments, though mostly positive, also have their share of the not so positive. One of these challenges is the difficulty in maintaining accuracy and quality of all the information, data gathered, aggregated or automatically generated being displayed on the Internet on Web websites or via mobile application, and this is a concern in the health domain. In this paper, we attempt to discuss in detail, some of the latest developments along with the challenges each of them entail and proposed Code of Conduct for health apps and connected objects.

  3. Interview with the Hon. Ken Wyatt: improving Indigenous health outcomes from a political viewpoint

    Directory of Open Access Journals (Sweden)

    Ken Wyatt

    2017-10-01

    Full Text Available In 2017, Australia celebrates 50 years since the 1967 referendum, when more than 90% of Australians voted to amend the constitution to allow the national government to create laws for Indigenous people and include them in the census. We spoke with the Honourable Ken Wyatt, the Minister for Indigenous Health and the Minister for Aged Care, about what has occurred over the past 50 years in Indigenous health from a political perspective, and what we have learnt to improve health outcomes in the future.

  4. Characterisation of recombinant pyranose oxidase from the cultivated mycorrhizal basidiomycete Lyophyllum shimeji (hon-shimeji

    Directory of Open Access Journals (Sweden)

    Yamabhai Montarop

    2010-07-01

    Full Text Available Abstract Background The flavin-dependent enzyme pyranose 2-oxidase (P2Ox has gained increased attention during the last years because of a number of attractive applications for this enzyme. P2Ox is a unique biocatalyst with high potential for biotransformations of carbohydrates and in synthetic carbohydrate chemistry. Recently, it was shown that P2Ox is useful as bioelement in biofuel cells, replacing glucose oxidase (GOx, which traditionally is used in these applications. P2Ox offers several advantages over GOx for this application, e.g., its much broader substrate specificity. Because of this renewed interest in P2Ox, knowledge on novel pyranose oxidases isolated from organisms other than white-rot fungi, which represent the traditional source of this enzyme, is of importance, as these novel enzymes might differ in their biochemical and physical properties. Results We isolated and over-expressed the p2ox gene encoding P2Ox from the ectomycorrhizal fungus Lyophyllum shimeji. The p2ox cDNA was inserted into the bacterial expression vector pET21a(+ and successfully expressed in E. coli Rosetta 2. We obtained active, flavinylated recombinant P2Ox in yields of approximately 130 mg per L of medium. The enzyme was purified by a two-step procedure based on anion exchange chromatography and preparative native PAGE, yielding an apparently homogenous enzyme preparation with a specific activity of 1.92 U/mg (using glucose and air oxygen as the substrates. Recombinant P2Ox from L. shimeji was characterized in some detail with respect to its physical and catalytic properties, and compared to the well-characterised enzymes from Phanerochaete chrysosporium and Trametes multicolor. Conclusion L. shimeji P2Ox shows properties that are comparable to those of P2Ox from white-rot fungal origin, and is in general characterised by lower Km and kcat values both for electron donor (sugar as well as electron acceptor (ferrocenium ion, 1,4-benzoquinone, 2,6-dichloroindophenol. While L. shimeji P2Ox is the least thermostable of these three enzymes (melting temperature Tm of 54.9°C; half-life time of activity τ1/2 of 0.12 at 50°C and pH 6.5, P. chrysosporium P2Ox showed remarkable thermostability with Tm of 75.4°C and τ1/2 of 96 h under identical conditions.

  5. Professor Barrie Vernon-Roberts, AO, MD, BSc, PhD, FRCPath, FRCPA, FAOrthA (Hon), FRS.SA.

    Science.gov (United States)

    Rainsford, K D; Haynes, D R

    2013-08-01

    This issue of Inflammopharmacology contains papers that have been submitted to commemorate the life and work of Professor Barrie Vernon-Roberts, an outstanding clinical scientist in the field of bone pathology and its pharmacological regulation. This review briefly summarizes his major works and achievements as well as a list of his publications.

  6. An investigation of the relationship between ethnicity and success in a BSc (Hons) Physiotherapy degree programme in the UK.

    Science.gov (United States)

    Williams, Annabel; Norris, Meriel; Cassidy, Elizabeth; Naylor, Sandra; Marston, Louise; Shiers, Pam

    2015-06-01

    To explore the potential relationship between ethnicity and achievement within undergraduate physiotherapy education. A retrospective analysis of assessment marks awarded for academic and clinical modules. A London University offering undergraduate physiotherapy education. Four hundred forty-eight undergraduate students enrolled onto the Physiotherapy honours degree programme between 2005 and 2009. Marks awarded following academic or clinical assessment. These were modelled through multivariable regression analysis to evaluate the relationship between marks awarded and ethnicity. Differences were noted between ethnic categories in final programme success and across academic and clinical modules. Our multivariable analysis demonstrated students from Asian backgrounds had decreased odds of succeeding compared with white British students (adjusted OR 0.43 95%CI 0.24, 0.79 P=0.006), as had Black students (adjusted OR 0.42 95%CI 0.19, 0.95 P=0.036) and students from Other ethnic backgrounds (adjusted OR 0.41 95%CI 0.20, 0.87 P=0.020). This analysis of undergraduate physiotherapy students illustrated a persistent difference in attainment between students from white British and those from BME backgrounds. Heterogeneity in academic outcomes both within and between minority ethnic groups was illustrated. This study not only reinforces the need to consider ethnicity within physiotherapy education but also raises further questions about why physiotherapy students from BME groups perform less well than their white British peers. Copyright © 2014. Published by Elsevier Ltd.

  7. FY 1988 report on the committee of the Coal Gasification Committee; 1988 nendo sekitan gaska iinkai hon'iinkai hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1989-03-01

    The paper reported activities of the committee of the Coal Gasification Committee in FY 1988. In the 1st committee meeting, report/discussion were made on the outline of the FY 1988 research plan on the coal gasification technology development. The distributed data were those on the development of entrained bed coal gasification power generation plant (the state of the development of a 200t/d gasification power generation pilot plant), the results of the operation using entrained bed coal gasification equipment, development of coal utilization hydrogen production technology (design/construction of pilot plant) and development of coal utilization hydrogen production technology (support study of pilot plant, study using small equipment). In the 2nd committee meeting, report/discussion were made on activities of sections such as the gasification power generation section and gasification technology section and the state of progress of the coal gasification technology development. The distributed data were those on the development of an entrained bed coal gasification power generation plant, support study of the development of an entrained bed coal gasification power generation plant, etc. (NEDO)

  8. A New Species of Cleisostoma (Orchidaceae) from the Hon Ba Nature Reserve in Vietnam: A Multidisciplinary Assessment

    Czech Academy of Sciences Publication Activity Database

    Ponert, J.; Trávníček, Pavel; Vuong, T. B.; Rybková, R.; Suda, Jan

    2016-01-01

    Roč. 11, č. 3 (2016), s. 1-23, č. článku e0150631. E-ISSN 1932-6203 Institutional support: RVO:67985939 Keywords : nectar sugar composition * molecular phylogenetics * aeridinae orchidaceae Subject RIV: EF - Botanics Impact factor: 2.806, year: 2016

  9. FY 1986 report on the committee of the Coal Gasification Committee; 1986 nendo sekitan gaska iinkai hon'iinkai hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1987-03-01

    The paper reported on activities of the committee of the Coal Gasification Committee in FY 1986. In the 1st Committee Meeting, after selecting the chairperson, report/discussion were made about the outline of the FY 1986 coal gasification technology development plan. The distributed data were the outline of the development of an entrained bed coal gasification power plant, outline of the development of a 40t/d fluidized bed coal gasification plant, outline of the design of a 1,000t/d 100,000KW-class demonstrative plant, outline of the development of coal utilization hydrogen production technology, and outline of the development of high-calorie gas production technology. In the 2nd Committee Meeting, report/discussion were made about activities of each section of the committee and the state of progress of the development of coal gasification technology. The distributed data were those on the development of an entrained bed coal gasification power plant, development of a 40t/d fluidized bed coal gasification plant, design of a 1,000t/d 100,000KW-class demonstrative plant, and development of coal utilization hydrogen production technology (design/construction of pilot plant, study using small equipment). (NEDO)

  10. Does Entry Route Really Affect Academic Outcome? Academic Achievement of Traditional versus Non Traditional Entrants to BN(Hons) Pre-Registration Nursing Programmes

    Science.gov (United States)

    Brimble, Mandy J.

    2015-01-01

    International trends for pre-registration nurse education at degree level alongside "widening access" initiatives mean that academic achievement of students entering via different educational routes is of interest to both higher and further education institutions. This article examines the academic achievement of students undertaking a…

  11. Detekce polymorfismu v genu MDR1 u ovčáckých a honáckých psů

    OpenAIRE

    Staroveská, Marieta

    2016-01-01

    This thesis is focused on polymorphism of MDR1 gene and related drug resistance. Resistance is caused by deletion of four nucleotids, that resulting in a frame shift and synthesis of nonfunctional transport of P-glycoprotein. The text describes a polymorphism of MDR1 (ABCB1) gene, which results in reduced resistance to drugs belonging to the group of macrocyclic lactones. It also describes inheritance of this phenomenon and it deals with the detection of mutation using PCR (polymerase chain r...

  12. Work-based learning for the creative industries: a case study of the development of BA (Hons) web design and social media

    OpenAIRE

    Riley, Tim

    2017-01-01

    Purpose: The purpose of this paper is to highlight the knowledge and insight gained building a work-based learning (WBL) Degree Apprenticeship developed through the HEFCE Catalyst Fund. Requirements of the funding stipulated that, in addition to work WBL provision, the course should be offered as a two-year fast-track. This was required to help reduce the increased financial burden placed on students, which arose from the substantial rise in HE tuition fees sanctioned by the UK coalition gove...

  13. Guillem Fabre, “Pus dels majors” (BdT 216.2; Id., “Hon mais vey, pus truep sordeyor” (BdT 216.1

    Directory of Open Access Journals (Sweden)

    Linda Paterson

    2013-03-01

    Full Text Available The historical circumstances of Guillem Fabre’s two surviving sirventes has given rise to widely divergent views. This essay builds on Parducci’s contextualisation of BdT 216.2 during the War of the Sicilian Vespers and the so-called Aragonese crusade by the French against Pere III of Aragon in 1284-1285. It argues that Guillem is likely to be referring to events say entre nos because Narbonne was the focal point of the gathering French army and preaching of the crusade. All other textual details are compatible with this period and best explained by this context. But while Parducci places the sirventes in May 1285, it must in fact have preceded the death of Martin IV on 29 March, since his speedily-appointed successor Honorius IV could not be blamed for not having preached a crusade against the heathen before the conflict degenerated into further atrocities. Furthermore a slightly earlier timing better explains the allusion to “the best-known man in the world”, the obvious candidate at this time being Charles of Anjou. Guillem probably composed BdT 216.2 during the build-up to war in 1284, before the death of Charles in January 1285, during the period of war preparations and propaganda speeches. It is also argued here that, pace Parducci, BdT 216.1 did not necessarily precede BdT 216.2.

  14. Fac

    African Journals Online (AJOL)

    USER

    2016-05-04

    May 4, 2016 ... Faculty of Environmental Science, Department of Environmental Planning and. Management ... scale, large scale, social and collective business ... The techniques and ... factors were selected for the statistical analysis. On this ...

  15. Lessons learned from fossil FAC assessments

    Energy Technology Data Exchange (ETDEWEB)

    Dooley, R. Barry; Shields, Kevin J. [Structural Integrity Associates, Inc., Oakville, ON (Canada); Shulder, Stephen J. [Structural Integrity Associates, Inc., Annapolis, MD (United States)

    2010-09-15

    In their work the authors have noted great diversity in the Flow-Accelerated Corrosion (FAC) Programs used at conventional fossil power plants. The results and findings of FAC Program assessments conducted at 22 conventional plants are summarized and discussed. By comparing the FAC Program characteristics and relevant unit features with damage and failure experiences, a number of common factors requiring attention from fossil utility organizations have been identified. The assessment experiences have also provided a picture of trends in specific FAC activities and general awareness within the conventional fossil fleet. One of the most important aspects of these studies is that while a few new locations of FAC have been found, there is some consolidation of the most frequently found locations. (orig.)

  16. Microfluidics microFACS for Life Detection

    Science.gov (United States)

    Platt, Donald W.; Hoover, Richard B.

    2010-01-01

    A prototype micro-scale Fluorescent Activated Cell Sorter (microFACS) for life detection has been built and is undergoing testing. A functional miniature microfluidics instrument with the ability to remotely distinguish live or dead bacterial cells from abiotic particulates in ice or permafrost of icy bodies of the solar system would be of fundamental value to NASA. The use of molecular probes to obtain the bio-signature of living or dead cells could answer the most fundamental question of Astrobiology: Does life exist beyond Earth? The live-dead fluorescent stains to be used in the microFACS instrument function only with biological cell walls. The detection of the cell membranes of living or dead bacteria (unlike PAH's and many other Biomarkers) would provide convincing evidence of present or past life. This miniature device rapidly examine large numbers of particulates from a polar ice or permafrost sample and distinguish living from dead bacteria cells and biological cells from mineral grains and abiotic particulates and sort the cells and particulates based on a staining system. Any sample found to exhibit fluorescence consistent with living cells could then be used in conjunction with a chiral labeled release experiment or video microscopy system to seek addition evidence for cellular metabolism or motility. Results of preliminary testing and calibration of the microFACS prototype instrument system with pure cultures and enrichment assemblages of microbial extremophiles will be reported.

  17. Joint stiffness identification of body structure using neural network. Jointed part composed of 2 beams; Neural network ni yoru shatai kozo no ketsugo gosei dotei. Buzai 2 hon kara naru ketsugobu no baai

    Energy Technology Data Exchange (ETDEWEB)

    Okabe, A; Tomioka, N [Nihon University, Tokyo (Japan)

    1997-10-01

    The method to obtain a joint stiffness value from displacements of jointed part using hierarchical neural networks in case of a jointed part composed of two beams were proposed. First, the sample data of displacements of jointed part vs. joint stiffness are prepared as learned data. Second, the relations between displacements of jointed part and joint stiffness are constructed from these learned data using a hierarchical neural networks. It was found that the value of joint stiffness can be obtained from displacement of jointed part by the trained neural network. 4 refs., 9 figs., 2 tabs.

  18. Development of movie caption translation lecture site using MobileMotion{sub TM}; MobileMotion{sub TM} wo mochiita jimaku hon'yaku koza site no kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    The site of Internet that performs the correspondence education for bringing up a movie caption translator was developed. Correspondence education that fully deepens understanding was obtained by distributing a motion picture using MPEG-4 distribution software (MobileMotion{sub TM}) and performing the learning based on bi-directional communication. HTML distribution and E-mail transmission and reception are done from Gaga Communications, and a MobileMotion{sub TM} file is distributed from the OnDemand Server of Toshiba. This reduces the communication traffic of heavy motion picture data. (translated by NEDO)

  19. A FPGA Implementation of the CAR-FAC Cochlear Model

    Directory of Open Access Journals (Sweden)

    Ying Xu

    2018-04-01

    Full Text Available This paper presents a digital implementation of the Cascade of Asymmetric Resonators with Fast-Acting Compression (CAR-FAC cochlear model. The CAR part simulates the basilar membrane's (BM response to sound. The FAC part models the outer hair cell (OHC, the inner hair cell (IHC, and the medial olivocochlear efferent system functions. The FAC feeds back to the CAR by moving the poles and zeros of the CAR resonators automatically. We have implemented a 70-section, 44.1 kHz sampling rate CAR-FAC system on an Altera Cyclone V Field Programmable Gate Array (FPGA with 18% ALM utilization by using time-multiplexing and pipeline parallelizing techniques and present measurement results here. The fully digital reconfigurable CAR-FAC system is stable, scalable, easy to use, and provides an excellent input stage to more complex machine hearing tasks such as sound localization, sound segregation, speech recognition, and so on.

  20. A FPGA Implementation of the CAR-FAC Cochlear Model.

    Science.gov (United States)

    Xu, Ying; Thakur, Chetan S; Singh, Ram K; Hamilton, Tara Julia; Wang, Runchun M; van Schaik, André

    2018-01-01

    This paper presents a digital implementation of the Cascade of Asymmetric Resonators with Fast-Acting Compression (CAR-FAC) cochlear model. The CAR part simulates the basilar membrane's (BM) response to sound. The FAC part models the outer hair cell (OHC), the inner hair cell (IHC), and the medial olivocochlear efferent system functions. The FAC feeds back to the CAR by moving the poles and zeros of the CAR resonators automatically. We have implemented a 70-section, 44.1 kHz sampling rate CAR-FAC system on an Altera Cyclone V Field Programmable Gate Array (FPGA) with 18% ALM utilization by using time-multiplexing and pipeline parallelizing techniques and present measurement results here. The fully digital reconfigurable CAR-FAC system is stable, scalable, easy to use, and provides an excellent input stage to more complex machine hearing tasks such as sound localization, sound segregation, speech recognition, and so on.

  1. A green emissive amorphous fac-Alq3 solid generated by grinding crystalline blue fac-Alq3 powder.

    Science.gov (United States)

    Bi, Hai; Chen, Dong; Li, Di; Yuan, Yang; Xia, Dandan; Zhang, Zuolun; Zhang, Hongyu; Wang, Yue

    2011-04-14

    A novel green emissive Alq(3) solid with a facial isomeric form has been obtained by grinding the typical blue luminescent fac-Alq(3) crystalline powder. This is the first report, to the best of our knowledge, that a fac-Alq(3) isomer emits green light.

  2. Project CHECO Southeast Asia Report. FAC Operations in Close Air Support Role in SVN

    National Research Council Canada - National Science Library

    Overton, James B

    1969-01-01

    This report addresses the role of the Forward Air Controller (FAC) in Southeast Asia. The various categories of FACs are discussed, including the function of the Ground FAC and the duties he performs...

  3. 76 FR 56760 - Granting of Request for Early Termination of the Waiting Period Under the Premerger Notification...

    Science.gov (United States)

    2011-09-14

    ... Trust; Lochinvar Corporation; Smith Family Voting Trust. 20111190 G WPP plc; Global Market Insite, Inc... Corporation. 20111272 G Hon Hai Precision Ind. Co. Ltd.; Cisco Systems, Inc.; Hon Hai Precision Ind. Co. Ltd...

  4. Putting the Teaching of American History and Civics Back in the Classroom. Hearing of the Committee on Health, Education, Labor, and Pensions, United States Senate. One Hundred Eighth Congress, First Session on Examining S. 504, To Establish Academies for Teachers and Students of American History and Civics and a National Alliance of Teachers of American History and Civics (April 10, 2003).

    Science.gov (United States)

    Congress of the U.S., Washington, DC. Senate Committee on Health, Education, Labor, and Pensions.

    Statements by the following individuals were given at this hearing and are presented in this document: Hon. Lamar Alexander; David McCullough; Hon. Robert Byrd; Bruce Cole; Eugene W. Hickok; James H. Billington; Diane Ravitch; Hon. Christopher J. Dodd; and Russell Berg accompanied by Peter Sullivan and Blanche Deaderick. Additional material…

  5. H.R. 4015, Jobs for Veterans Act. Hearing before the Subcommittee on Benefits of the Committee on Veterans' Affairs, House of Representatives. One Hundred Seventh Congress, Second Session (April 18, 2002).

    Science.gov (United States)

    Congress of the U.S., Washington, DC. House Committee on Veterans' Affairs.

    This hearing provides the statements from the following individuals: Chairman Simpson; Hon. Silvestre Reyes; Hon. Ander Crenshaw; and Hon. Lane Evans (prepared statement of). This document also includes statements from over 10 wittinesses and contains an article, bill, chart, and statement submitted for the record relating to this hearing.…

  6. EquiFACS: The Equine Facial Action Coding System.

    Directory of Open Access Journals (Sweden)

    Jen Wathan

    Full Text Available Although previous studies of horses have investigated their facial expressions in specific contexts, e.g. pain, until now there has been no methodology available that documents all the possible facial movements of the horse and provides a way to record all potential facial configurations. This is essential for an objective description of horse facial expressions across a range of contexts that reflect different emotional states. Facial Action Coding Systems (FACS provide a systematic methodology of identifying and coding facial expressions on the basis of underlying facial musculature and muscle movement. FACS are anatomically based and document all possible facial movements rather than a configuration of movements associated with a particular situation. Consequently, FACS can be applied as a tool for a wide range of research questions. We developed FACS for the domestic horse (Equus caballus through anatomical investigation of the underlying musculature and subsequent analysis of naturally occurring behaviour captured on high quality video. Discrete facial movements were identified and described in terms of the underlying muscle contractions, in correspondence with previous FACS systems. The reliability of others to be able to learn this system (EquiFACS and consistently code behavioural sequences was high--and this included people with no previous experience of horses. A wide range of facial movements were identified, including many that are also seen in primates and other domestic animals (dogs and cats. EquiFACS provides a method that can now be used to document the facial movements associated with different social contexts and thus to address questions relevant to understanding social cognition and comparative psychology, as well as informing current veterinary and animal welfare practices.

  7. Six key elements' analysis of FAC effective management in nuclear power plant

    International Nuclear Information System (INIS)

    Zhong Zhaojiang; Chen Hanming

    2010-01-01

    Corporate Commitment, Analysis, Operating Experience, Inspection, Training and Engineering Judgment, Long-Term Strategy are the six key elements of FAC effective management in nuclear power plant. Corporate commitment is the economy base of FAC management and ensure of management system, Analysis is the method of FAC's optimization and consummation, Operating experience is the reference and complementarity of FAC, Inspection is the base of accumulating FAC data, Training and engineering judgment is the technical complementarity and deepening, Long-term strategy is successful key of FAC management. Six key elements supplement each other, and make up of a full system of FAC effective management. For present FAC management in our national nuclear power plant, six key elements are the core and bring out the best in each other to found the FAC effective management system and prevent great FAC occurrence. (authors)

  8. Ion acoustic instability of HPT particles, FAC density, anomalous ...

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    electromagnetic field grow at the expense of the electron kinetic energy and as a result, vari- ous instabilities set in. The magnetometer data indicate that these waves are spatially corre- lated with perturbations; we interpret them as field aligned current (FAC) layers directed into and out of the auroral ionosphere. Kinetic the-.

  9. Impact of flow accelerated corrosion (FAC) on feeder refurbishment planning

    International Nuclear Information System (INIS)

    Jyrkama, M.; Pandey, M.

    2010-01-01

    Feeder wall thinning due to flow accelerated corrosion (FAC) may result in a large number of feeder replacements in the future. In this study, the process of FAC is modelled using a probabilistic approach and used to predict the expected number of degraded feeders and their replacements in the future. Because of the high cost associated with feeder replacements, it may be optimal to replace the entire feeder population during a single refurbishment outage when the unit cost of replacement is likely to be less. The results of this study demonstrate, however, that the unit cost of feeder replacement must be sufficiently lower than the standard replacement cost and the refurbishment performed at an optimal time to realize the economic benefits associated with the refurbishment. (author)

  10. MAC/FAC: A Model of Similarity-Based Retrieval

    Science.gov (United States)

    1994-10-01

    Grapes (0.28) 327 Sour Grapes, analog The Taming of the Shrew (0.22), Merry Wives 251 (0.18), S[11 stories], Sour Grapes (-0.19) Sour Grapes, literal... The Institute for the 0 1 Learning Sciences Northwestern University CD• 00 MAC/FAC: A MODEL OF SIMILARITY-BASED RETRIEVAL Kenneth D. Forbus Dedre...Gentner Keith Law Technical Report #59 • October 1994 94-35188 wit Establisthed in 1989 with the support of Andersen Consulting Form Approved REPORT

  11. Fibro/Adipogenic Progenitors (FAPs): Isolation by FACS and Culture.

    Science.gov (United States)

    Low, Marcela; Eisner, Christine; Rossi, Fabio

    2017-01-01

    Fibro/adipogenic progenitors (FAPs ) are tissue-resident mesenchymal stromal cells (MSCs). Current literature supports a role for these cells in the homeostasis and repair of multiple tissues suggesting that FAPs may have extensive therapeutic potential in the treatment of numerous diseases. In this context, it is crucial to establish efficient and reproducible procedures to purify FAP populations from various tissues. Here, we describe a protocol for the isolation and cell culture of FAPs from murine skeletal muscle using fluorescence -activated cell sorting (FACS), which is particularly useful for experiments where high cell purity is an essential requirement. Identification, isolation, and cell culture of FAPs represent powerful tools that will help us to understand the role of these cells in different conditions and facilitate the development of safe and effective new treatments for diseases.

  12. Blend Shape Interpolation and FACS for Realistic Avatar

    Science.gov (United States)

    Alkawaz, Mohammed Hazim; Mohamad, Dzulkifli; Basori, Ahmad Hoirul; Saba, Tanzila

    2015-03-01

    The quest of developing realistic facial animation is ever-growing. The emergence of sophisticated algorithms, new graphical user interfaces, laser scans and advanced 3D tools imparted further impetus towards the rapid advancement of complex virtual human facial model. Face-to-face communication being the most natural way of human interaction, the facial animation systems became more attractive in the information technology era for sundry applications. The production of computer-animated movies using synthetic actors are still challenging issues. Proposed facial expression carries the signature of happiness, sadness, angry or cheerful, etc. The mood of a particular person in the midst of a large group can immediately be identified via very subtle changes in facial expressions. Facial expressions being very complex as well as important nonverbal communication channel are tricky to synthesize realistically using computer graphics. Computer synthesis of practical facial expressions must deal with the geometric representation of the human face and the control of the facial animation. We developed a new approach by integrating blend shape interpolation (BSI) and facial action coding system (FACS) to create a realistic and expressive computer facial animation design. The BSI is used to generate the natural face while the FACS is employed to reflect the exact facial muscle movements for four basic natural emotional expressions such as angry, happy, sad and fear with high fidelity. The results in perceiving the realistic facial expression for virtual human emotions based on facial skin color and texture may contribute towards the development of virtual reality and game environment of computer aided graphics animation systems.

  13. 48 CFR 301.603-72 - FAC-C and HHS SAC certification requirements.

    Science.gov (United States)

    2010-10-01

    ... HUMAN SERVICES GENERAL HHS ACQUISITION REGULATION SYSTEM Career Development, Contracting Authority, and... retention of certification, including the requirement to earn continuous learning points (CLPs). FAC-C... to employees for the first time at a department or agency.) (c) The FAC-C certification is based on...

  14. Effect of Cr content on the FAC of pipe material at 150 .deg. C

    International Nuclear Information System (INIS)

    Park, Tae Jun; Kim, Hong Pyo

    2013-01-01

    Flow accelerated corrosion (FAC) of the carbon steel piping in nuclear power plants (NPPs) has been major issue in nuclear industry. During the FAC, a protective oxide layer on carbon steel dissolves into flowing water leading to a thinning of the oxide layer and accelerating corrosion of base material. As a result, severe failures may occur in the piping and equipment of NPPs. Effect of alloying elements on FAC of pipe materials was studied with rotating cylinder FAC test facility at 150 .deg. C and at flow velocity of 4m/s. The facility is equipped with on line monitoring of pH, conductivity, dissolved oxygen(DO) and temperature. Test solution was the demineralized water, and DO concentration was less than 1 ppb. Surface appearance of A 106 Gr. B which is used widely in secondary pipe in NPPs showed orange peel appearance, typical appearance of FAC. The materials with Cr content higher than 0.17wt.% showed pit. The pit is thought to early degradation mode of FAC. The corrosion product within the pit was enriched with Cr, Mo, Cu, Ni and S. But S was not detected in SA336 F22V with 2.25wt.% Cr. The enrichment of Cr and Mo seemed to be related with low, solubility of Cr and Mo compared to Fe. Measured FAC rate was compared with Ducreaux's relationship and showed slightly lower FAC rate than Ducreaux's relationship

  15. A new FACS approach isolates hESC derived endoderm using transcription factors.

    Directory of Open Access Journals (Sweden)

    Yuqiong Pan

    2011-03-01

    Full Text Available We show that high quality microarray gene expression profiles can be obtained following FACS sorting of cells using combinations of transcription factors. We use this transcription factor FACS (tfFACS methodology to perform a genomic analysis of hESC-derived endodermal lineages marked by combinations of SOX17, GATA4, and CXCR4, and find that triple positive cells have a much stronger definitive endoderm signature than other combinations of these markers. Additionally, SOX17(+ GATA4(+ cells can be obtained at a much earlier stage of differentiation, prior to expression of CXCR4(+ cells, providing an important new tool to isolate this earlier definitive endoderm subtype. Overall, tfFACS represents an advancement in FACS technology which broadly crosses multiple disciplines, most notably in regenerative medicine to redefine cellular populations.

  16. 77 FR 43821 - Records Governing Off-the-Record Communications

    Science.gov (United States)

    2012-07-26

    ...-515-000 7-9-12 Michael Mojica \\2\\. 3. CP08-6-000 7-11-12 David J. Devine. 4. CP11-161-000 7-13-12...\\ Email record. \\6\\ Hons. Robert P. Casey, Jr. and Tom Marino. Dated: July 20, 2012. Nathaniel J. Davis... \\5\\. 3. P-2458-000 6-27-12 Hon. Michael H. Michaud. 4. CP11-161-000 6-27-12 Hon. Tom Marino. 5. P...

  17. Humanoid Robot Head Design Based on Uncanny Valley and FACS

    Directory of Open Access Journals (Sweden)

    Jizheng Yan

    2014-01-01

    Full Text Available Emotional robots are always the focus of artificial intelligence (AI, and intelligent control of robot facial expression is a hot research topic. This paper focuses on the design of humanoid robot head, which is divided into three steps to achieve. The first step is to solve the uncanny valley about humanoid robot, to find and avoid the relationship between human being and robot; the second step is to solve the association between human face and robot head; compared with human being and robots, we analyze the similarities and differences and explore the same basis and mechanisms between robot and human analyzing the Facial Action Coding System (FACS, which guides us to achieve humanoid expressions. On the basis of the previous two steps, the third step is to construct a robot head; through a series of experiments we test the robot head, which could show some humanoid expressions; through human-robot interaction, we find people are surprised by the robot head expression and feel happy.

  18. Individualized FAC on bottom tab subassemblies to minimize adhesive gap between emitter and optics

    Science.gov (United States)

    Sauer, Sebastian; Müller, Tobias; Haag, Sebastian; Beleke, Andreas; Zontar, Daniel; Baum, Christoph; Brecher, Christian

    2017-02-01

    High Power Diode Laser (HPDL) systems with short focal length fast-axis collimators (FAC) require submicron assembly precision. Conventional FAC-Lens assembly processes require adhesive gaps of 50 microns or more in order to compensate for component tolerances (e.g. deviation of back focal length) and previous assembly steps. In order to control volumetric shrinkage of fast-curing UV-adhesives shrinkage compensation is mandatory. The novel approach described in this paper aims to minimize the impact of volumetric shrinkage due to the adhesive gap between HPDL edge emitters and FAC-Lens. Firstly, the FAC is actively aligned to the edge emitter without adhesives or bottom tab. The relative position and orientation of FAC to emitter are measured and stored. Consecutively, an individual subassembly of FAC and bottom tab is assembled on Fraunhofer IPT's mounting station with a precision of +/-1 micron. Translational and lateral offsets can be compensated, so that a narrow and uniform glue gap for the consecutive bonding process of bottom tab to heatsink applies (Figure 4). Accordingly, FAC and bottom tab are mounted to the heatsink without major shrinkage compensation. Fraunhofer IPT's department assembly of optical systems and automation has made several publications regarding active alignment of FAC lenses [SPIE LASE 8241-12], volumetric shrinkage compensation [SPIE LASE 9730-28] and FAC on bottom tab assembly [SPIE LASE 9727-31] in automated production environments. The approach described in this paper combines these and is the logical continuation of that work towards higher quality of HPDLs.

  19. Safe sorting of GFP-transduced live cells for subsequent culture using a modified FACS vantage

    DEFF Research Database (Denmark)

    Sørensen, T U; Gram, G J; Nielsen, S D

    1999-01-01

    BACKGROUND: A stream-in-air cell sorter enables rapid sorting to a high purity, but it is not well suited for sorting of infectious material due to the risk of airborne spread to the surroundings. METHODS: A FACS Vantage cell sorter was modified for safe use with potentially HIV infected cells...... culture. CONCLUSIONS: Sorting of live infected cells can be performed safely and with no deleterious effects on vector expression using the modified FACS Vantage instrument....

  20. Current state of micro machine technologies and summary of its research and development. ; Research and development of the project requiring coordination among industries, government and universities, and international cooperation. Micro machine gijutsu no genjo to kenkyu kaihatsu no gaiyo. ; Hon project no kenkyu kaihatsu ni wa sankangaku no renkei to kokusai kyoryoku ga juyo

    Energy Technology Data Exchange (ETDEWEB)

    Konaka, M [Agency of Industrial Science and Technology, Tokyo (Japan)

    1991-11-15

    A summary is given on the current state of micro machine (MM) technologies and its research and development. The large scale project system was inaugurated in 1966 under the coordinations among the industries, government and universities. The MM technology creates micro movement mechanisms using IC{prime}s in place of electronic circuits. The subject is to perform an IC manufacturing process which can process IC{prime}s three-dimensionally and assemble them simultaneously, and the product strength. The target is a systematization of constitutive elements ultra small, yet high in performance. This requires an international cooperation. The future MM image would include those that enter blood vessels and organs to help operations with only a small amount of incision, and those that enter power plant boiler piping and aircraft engines to perform inspection and repair without a need of dismantling. Problems to be solved relate to the MM movement mechanisms, modules having environment recognizing function, small-size energy converters, wireless transmission technologies, and dynamics in microscopic regions.

  1. Dinámica de materia orgánica en el Parque Natural El Hon­do de Elche-Crevillente (España Dynamics of organic matter in the Nature Reserve El Hondo de Elche-Crevillente (Spain

    Directory of Open Access Journals (Sweden)

    P. Córdoba

    2010-01-01

    Full Text Available Se estudió la variabilidad espacio­temporal de carbono orgánico en suelos del Parque Natural El Hondo de Elche-Crevillente en relación con la evolución en el tiempo y con el tipo de cubiertas vegetales. A su vez, se analizan los posi­bles cambios en el tiempo asociados al uso y a la gestión del territorio. Los resul­tados mostraron diferencias significativas (ANOVA pThe space-temporary organic carbon variability was studied in soils from Na­ture Reserve El Hondo in relation with its time evolution and with the vegetation covers. At the same time, the possible changes produced along the time associ­ated with the use and management of the territory were analyzed. The results re­vealed significant differences between su­perficial covers and periods of sampling (ANOVA p<0.05. The great diversity of covers and the anthropic use manifested the great space-temporary differences in the organic carbon content of these soils and the possibilities of sequestration of carbon in different soils present at the same environment.

  2. Spectroscopic Characterization of Aqua [ fac-Tc(CO)3]+ Complexes at High Ionic Strength.

    Science.gov (United States)

    Chatterjee, Sayandev; Hall, Gabriel B; Engelhard, Mark H; Du, Yingge; Washton, Nancy M; Lukens, Wayne W; Lee, Sungsik; Pearce, Carolyn I; Levitskaia, Tatiana G

    2018-06-05

    Understanding fundamental Tc chemistry is important to both the remediation of nuclear waste and the reprocessing of nuclear fuel; however, current knowledge of the electronic structure and spectral signatures of low-valent Tc compounds significantly lags behind the remainder of the d-block elements. In particular, identification and treatment of Tc speciation in legacy nuclear waste is challenging due to the lack of reference data especially for Tc compounds in the less common oxidation states (I-VI). In an effort to establish a spectroscopic library corresponding to the relevant conditions of extremely high ionic strength typical for the legacy nuclear waste, compounds with the general formula of [ fac-Tc(CO) 3 (OH 2 ) 3- n (OH) n ] 1- n (where n = 0-3) were examined by a range of spectroscopic techniques including 99 Tc/ 13 C NMR, IR, XPS, and XAS. In the series of monomeric aqua species, stepwise hydrolysis results in the increase of the Tc metal center electron density and corresponding progressive decrease of the Tc-C bond distances, Tc electron binding energies, and carbonyl stretching frequencies in the order [ fac-Tc(CO) 3 (OH 2 ) 3 ] + > [ fac-Tc(CO) 3 (OH 2 ) 2 (OH)] > [ fac-Tc(CO) 3 (OH 2 )(OH) 2 ] - . These results correlate with established trends of the 99 Tc upfield chemical shift and carbonyl 13 C downfield chemical shift. The lone exception is [ fac-Tc(CO) 3 (OH)] 4 which exhibits a comparatively low electron density at the metal center attributed to the μ 3 -bridging nature of the - OH ligands causing less σ-donation and no π-donation. This work also reports the first observations of these compounds by XPS and [ fac-Tc(CO) 3 Cl 3 ] 2- by XAS. The unique and distinguishable spectral features of the aqua [ fac-Tc(CO) 3 ] + complexes lay the foundation for their identification in the complex aqueous matrixes.

  3. An alternate approach to calibrating FAC-predictive models using inspection data (Log Book No. 398)

    International Nuclear Information System (INIS)

    Pulido, J.E.; Ksiazek, P.E.; Alecksick, R.M.

    2004-01-01

    Flow-Accelerated Corrosion (FAC) of piping and fittings in Nuclear Energy Plants can pose a threat to personnel safety, reduce plant availability, and result in undesirable challenges to plant safety systems. For these reasons, accurate predictions of FAC-induced wear rates are extremely valuable in that they allow action to be taken prior to component failure. The EPRI recommended method of predicting FAC wear rates for inspected as well as uninspected components allows for calibration of predictions through the use of wall thickness measurements obtained from UT inspections. This method uses a simple linear correction based on the median value of the ratio of measured to predicted thickness. An alternate approach is presented that takes local thermodynamic variations into account, thus resulting in an improved correlation with measured data. (author)

  4. New Fellows and Honorary Fellow

    Indian Academy of Sciences (India)

    FNASc., Hon. FIEI, Hon. FNA Engg., for Assoc. US Natl Acad. Engg.,. Council Service: 1971-91, President: 1977-79, Vice President: 1974-76. Date of birth: 25 September 1920. Date of death: 3 January 2002. Specialization: Aerospace Engineering and Fluid Mechanics Last known address: Member, Space Commission, ...

  5. HONSU, a protein phosphatase 2C, regulates seed dormancy by inhibiting ABA signaling in Arabidopsis.

    Science.gov (United States)

    Kim, Woohyun; Lee, Yeon; Park, Jeongmoo; Lee, Nayoung; Choi, Giltsu

    2013-04-01

    Seed dormancy, a seed status that prohibits germination even in the presence of inductive germination signals, is a poorly understood process. To identify molecular components that regulate seed dormancy, we screened T-DNA insertion lines and identified a mutant designated honsu (hon). HON loss-of-function mutants display deep seed dormancy, whereas HON-overexpressing lines display shallow seed dormancy. HON encodes a seed-specific group A phosphatase 2C (PP2C) and is one of the major negative regulators of seed dormancy among group A PP2Cs. Like other PP2C family members, HON interacts with PYR1/RCAR11 in the presence of ABA. Our analysis indicates that HON inhibits ABA signaling and activates gibberellic acid signaling, and both of these conditions must be satisfied to promote the release of seed dormancy. However, HON mRNA levels are increased in mutants displaying deep seed dormancy or under conditions that deepen seed dormancy, and decreased in mutants displaying shallow seed dormancy or under conditions that promote the release of seed dormancy. Taken together, our results indicate that the expression of HON mRNA is homeostatically regulated by seed dormancy.

  6. 7 CFR 1945.18 - United States Department of Agriculture (USDA) Food and Agriculture Council (FAC).

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 13 2010-01-01 2009-01-01 true United States Department of Agriculture (USDA) Food and Agriculture Council (FAC). 1945.18 Section 1945.18 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE...

  7. Genome editing using FACS enrichment of nuclease-expressing cells and indel detection by amplicon analysis

    DEFF Research Database (Denmark)

    Lonowski, Lindsey A; Narimatsu, Yoshiki; Riaz, Anjum

    2017-01-01

    , FACS enrichment of cells expressing nucleases linked to fluorescent proteins can be used to maximize knockout or knock-in editing efficiencies or to balance editing efficiency and toxic/off-target effects. The two methods can be combined to form a pipeline for cell-line editing that facilitates...

  8. Crystal structures of fac-trichloridotris(trimethylphosphane-κPrhodium(III monohydrate and fac-trichloridotris(trimethylphosphane-κPrhodium(III methanol hemisolvate: rhodium structures that are isotypic with their iridium analogs

    Directory of Open Access Journals (Sweden)

    Joseph S. Merola

    2015-02-01

    Full Text Available The crystal structures of two solvates of fac-trichloridotris(trimethylphosphane-κPrhodium(III are reported, i.e. one with water in the crystal lattice, fac-[RhCl3(Me3P3]·H2O, and one with methanol in the crystal lattice, fac-[RhCl3(Me3P3]·0.5CH3OH. These rhodium compounds exhibit distorted octahedral coordination spheres at the metal and are isotypic with the analogous iridium compounds previously reported by us [Merola et al. (2013. Polyhedron, 54, 67–73]. Comparison is made between the rhodium and iridium compounds, highlighting their isostructural relationships.

  9. Crystal structures of fac-tri?chlorido?tris?(tri?methyl?phosphane-?P)rhodium(III) monohydrate and fac-tri?chlorido?tris?(tri?methyl?phosphane-?P)rhodium(III) methanol hemisolvate: rhodium structures that are isotypic with their iridium analogs

    OpenAIRE

    Merola, Joseph S.; Franks, Marion A.

    2015-01-01

    The crystal structures of two solvates of fac-tri-chlorido-tris-(tri-methyl-phosphane-κP)rhodium(III) are reported, i.e. one with water in the crystal lattice, fac-[RhCl3(Me3P)3]·H2O, and one with methanol in the crystal lattice, fac-[RhCl3(Me3P)3]·0.5CH3OH. These rhodium compounds exhibit distorted octahedral coordination spheres at the metal and are isotypic with the analogous iridium compounds previously reported by us [Merola et al. (2013 ▶). Polyhedron, 54, 67-73]. Comparison is made bet...

  10. The influence of IMF cone angle on invariant latitudes of polar region footprints of FACs in the magnetotail: Cluster observatio

    Science.gov (United States)

    Cheng, Z.; Shi, J.; Zhang, J.; Kistler, L. M.

    2017-12-01

    The influence of the interplanetary magnetic field (IMF) cone angle θ (the angle between the IMF direction and the Sun-Earth line) on the invariant latitudes (ILATs) of the footprints of the field-aligned currents (FACs) in the magnetotail has been investigated. We performed a statistic study of 542 FAC cases observed by the four Cluster spacecraft in the northern hemisphere. The results show that the large FAC (>10 nA/m2) cases occur at the low ILATs (60º, which implies the footprints of the large FACs mainly expand equatorward with large IMF cone angle. The equatorward boundary of the FAC footprints in the polar region decreases with the IMF cone angle especially when IMF Bz is positive. There is almost no correlation or a weak positive correlation of the poleward boundary and IMF cone angle no matter IMF is northward or southward. The equatorward boundary is more responsive to the IMF cone angle. Compared to the equatorward boundary, the center of the FAC projected location changes very little. This is the first time a correlation between FAC projected location and IMF cone angle has been determined.

  11. Nickel coated flyash (Ni-FAC) cenosphere doped polyaniline composite film for electromagnetic shielding

    International Nuclear Information System (INIS)

    Bora, Pritom J; Ramamurthy, Praveen C; Madras, Giridhar; Vinoy, K J; Kishore

    2015-01-01

    A solid waste material fly ash cenosphere (FAC) was nickel coated and polyaniline in situ polymerized at −30 ± 2 °C in nitrogen atmosphere. A thin film of this composite material was prepared by solution processing and surface morphology/topography was studied. High electromagnetic shielding effectiveness (SE) was obtained for this film; 59 ± 4 μm and 133 ± 4 μm films show an average of 38 and 60 dB SE, respectively, in the frequency range 8.2–12.4 GHz (X-band). Unlike PANI film, the SE of these composite films is high at high frequency. The presence of magneto dielectric microsphere (Ni-FAC) increases the heterogeneity of the composite film in an efficient way for EMI shielding by changing film topography and increasing ac conductivity and permeability. (paper)

  12. Re-casting the FAC Net: People, Platforms, and Policy in Forward Air Control

    Science.gov (United States)

    2015-06-01

    Storm, technological advances, such as satellite communications and the global positioning system (GPS), provided the architecture to distribute...space-based technologies aided the creation of a communications architecture that transformed the FAC mission. By the onset of hostilities in OEF...modern battlefield.2 The Egyptians employed Soviet anti-tank missiles, which demonstrated to Army and Air Force leaders that the Army must improve

  13. Automated assembly of fast-axis collimation (FAC) lenses for diode laser bar modules

    Science.gov (United States)

    Miesner, Jörn; Timmermann, Andre; Meinschien, Jens; Neumann, Bernhard; Wright, Steve; Tekin, Tolga; Schröder, Henning; Westphalen, Thomas; Frischkorn, Felix

    2009-02-01

    Laser diodes and diode laser bars are key components in high power semiconductor lasers and solid state laser systems. During manufacture, the assembly of the fast axis collimation (FAC) lens is a crucial step. The goal of our activities is to design an automated assembly system for high volume production. In this paper the results of an intermediate milestone will be reported: a demonstration system was designed, realized and tested to prove the feasibility of all of the system components and process features. The demonstration system consists of a high precision handling system, metrology for process feedback, a powerful digital image processing system and tooling for glue dispensing, UV curing and laser operation. The system components as well as their interaction with each other were tested in an experimental system in order to glean design knowledge for the fully automated assembly system. The adjustment of the FAC lens is performed by a series of predefined steps monitored by two cameras concurrently imaging the far field and the near field intensity distributions. Feedback from these cameras processed by a powerful and efficient image processing algorithm control a five axis precision motion system to optimize the fast axis collimation of the laser beam. Automated cementing of the FAC to the diode bar completes the process. The presentation will show the system concept, the algorithm of the adjustment as well as experimental results. A critical discussion of the results will close the talk.

  14. Free-air ionization chamber, FAC-IR-300, designed for medium energy X-ray dosimetry

    International Nuclear Information System (INIS)

    Mohammadi, S.M.; Tavakoli-Anbaran, H.; Zeinali, H.Z.

    2017-01-01

    The primary standard for X-ray photons is based on parallel-plate free-air ionization chamber (FAC). Therefore, the Atomic Energy Organization of Iran (AEOI) is tried to design and build the free-air ionization chamber, FAC-IR-300, for low and medium energy X-ray dosimetry. The main aim of the present work is to investigate specification of the FAC-IR-300 ionization chamber and design it. FAC-IR-300 dosimeter is composed of two parallel plates, a high voltage (HV) plate and a collector plate, along with a guard electrode that surrounds the collector plate. The guard plate and the collector were separated by an air gap. For obtaining uniformity in the electric field distribution, a group of guard strips was used around the ionization chamber. These characterizations involve determining the exact dimensions of the ionization chamber by using Monte Carlo simulation and introducing correction factors.

  15. Design of the free-air ionization chamber, FAC-IR-150, for X-ray dosimetry

    Science.gov (United States)

    Mohammadi, Seyed Mostafa; Tavakoli-Anbaran, Hossein

    2018-03-01

    The primary standard for X-ray dosimetry is based on the free-air ionization chamber (FAC). Therefore, the Atomic Energy Organization of Iran (AEOI) designed the free-air ionization chamber, FAC-IR-150, for low and medium energy X-ray dosimetry. The purpose of this work is the study of the free-air ionization chamber characteristics and the design of the FAC-IR-150. The FAC-IR-150 dosimeter has two parallel plates, a high voltage plate and a collector plate. A guard electrode surrounds the collector and is separated by an air gap. A group of guard strips is used between up and down electrodes to produce a uniform electric field in all the ion chamber volume. This design involves introducing the correction factors and determining the exact dimensions of the ionization chamber by using Monte Carlo simulation.

  16. Quality of Health Information on the Internet for Urolithiasis on the Google Search Engine.

    Science.gov (United States)

    Chang, Dwayne T S; Abouassaly, Robert; Lawrentschuk, Nathan

    2016-01-01

    Purpose . To compare the quality of health information on the Internet for keywords related to urolithiasis, to assess for difference in information quality across four main Western languages, and to compare the source of sponsorship in these websites. Methods . Health On the Net (HON) Foundation principles were utilised to determine quality information. Fifteen keywords related to urolithiasis were searched on the Google search engine. The first 150 websites were assessed against the HON principles and the source of sponsorship determined. Results . A total of 8986 websites were analysed. A proportion of HON-accredited websites for individual search terms range between 2.5% and 12.0%. The first 50 websites were more likely to be HON-positive compared to websites 51-100 and 101-150. French websites searched were more likely to be HON-positive whereas German websites were less likely to be HON-positive than English websites. There was no statistically significant difference between the rate of HON-positive English and Spanish websites. The three main website sponsors were from government/educational sources (40.2%), followed by commercial (29.9%) and physician/surgeon sources (18.6%). Conclusions . Health information on most urolithiasis websites was not validated. Nearly one-third of websites in this study have commercial sponsorship. Doctors should recognise the need for more reliable health websites for their patients.

  17. Effects of water chemistry and fluid dynamics on wall thinning behavior. Part 1. Development of FAC model focused on water chemistry and composition of material

    International Nuclear Information System (INIS)

    Fujiwara, Kazutoshi; Domae, Masafumi; Ohta, Joji; Yoneda, Kimitoshi; Inada, Fumio

    2009-01-01

    Flow Accelerated Corrosion (FAC), which is one of the important subjects at fossil and nuclear power plans, is caused by the accelerated dissolution of protective oxide film due to the turbulent flow. The influence factors on FAC such as water chemistry, material, and fluid dynamics are closely related to the oxide property so that the risk of FAC can be reduced by the suitable control of water chemistry. There are some FAC models and evaluation codes of FAC rate. Some of them are used in wall thinning management of nuclear power plant in some country. Nevertheless, these FAC codes include many empirical parameters so that some uncertainty to evaluate the synergistic effectiveness of factors are the controversial point for the application of FAC code to wall thinning management in Japanese nuclear power plant. In this study, a FAC model that can evaluate the effect of temperature, NH3 concentration, chromium content, and dissolved oxygen concentration on FAC rate was developed by considering the diffusion of dissolved species. The critical dissolved oxygen concentration, which can inhibit FAC, was also calculated by this model. (author)

  18. A new methodology for the study of FAC phenomenon based on a fuzzy rule system

    International Nuclear Information System (INIS)

    Ferreira Guimaraes, Antonio Cesar

    2003-01-01

    This work consists of the representation of the corrosion problem, FAC - 'Flow-Accelerated Corrosion' in components, structures and passive systems in a nuclear power plant with aging, through a fuzzy rules system, in substitution to the conventional modeling and experimental analyses. Using data characteristic of the nature of the problem to be analyzed, a reduced number of rules can be establish to represent the actual problem. The results can be visualized in a very satisfactory way thus providing the engineer with the knowledge to work in the space of solution of rules to do the necessary inferences

  19. fac-Tris(pyridine-2-carboxylato-κ2N,Ocobalt(III

    Directory of Open Access Journals (Sweden)

    Irina A. Golenia

    2011-11-01

    Full Text Available In the title compound, [Co(C6H4NO23], the CoIII ion lies on a threefold rotation axis and is in a distorted octahedral environment defined by three N and three O donor atoms from three fac-disposed pyridine-2-carboxylate ligands. The ligands are coordinated in a chelate fashion, forming three five-membered rings. In the crystal, translationally related complex molecules are organized into columns along [001] via C—H...O hydrogen bonds.

  20. fac-Tris(pyridine-2-carboxyl­ato-κ2 N,O)cobalt(III)

    Science.gov (United States)

    Golenia, Irina A.; Boyko, Alexander N.; Kotova, Natalia V.; Haukka, Matti; Kalibabchuk, Valentina A.

    2011-01-01

    In the title compound, [Co(C6H4NO2)3], the CoIII ion lies on a threefold rotation axis and is in a distorted octa­hedral environment defined by three N and three O donor atoms from three fac-disposed pyridine-2-carboxyl­ate ligands. The ligands are coordinated in a chelate fashion, forming three five-membered rings. In the crystal, translationally related complex molecules are organized into columns along [001] via C—H⋯O hydrogen bonds. PMID:22219826

  1. Plant volatile eliciting FACs in lepidopteran caterpillars, fruit flies and crickets: a convergent evolution or phylogenetic inheritance?

    Directory of Open Access Journals (Sweden)

    Naoko eYoshinaga

    2014-04-01

    Full Text Available Fatty acid amino acid conjugates (FACs, first identified in lepidopteran caterpillar spit as elicitors of plant volatile emission, also have been reported as major components in gut tracts of Drosophila melanogaster and cricket Teleogryllus taiwanemma. The profile of FAC analogs in these two insects was similar to that of tobacco hornworm Manduca sexta, showing glutamic acid conjugates predominantly over glutamine conjugates. The physiological function of FACs is presumably to enhance nitrogen assimilation in Spodoptera litura larvae, but in other insects it is totally unknown. Whether these insects share a common synthetic mechanism of FACs is also unclear. In this study, the biosynthesis of FACs was examined in vitro in five lepidopteran species (M. sexta, Cephonodes hylas, silkworm, S. litura, and Mythimna separata, fruit fly larvae and T. taiwanemma. The fresh midgut tissues of all of the tested insects showed the ability to synthesize glutamine conjugates in vitro when incubated with glutamine and sodium linolenate. Such direct conjugation was also observed for glutamic acid conjugates in all the insects but the product amount was very small and did not reflect the in vivo FAC patterns in each species. In fruit fly larvae, the predominance of glutamic acid conjugates could be explained by a shortage of substrate glutamine in midgut tissues, and in M. sexta, a rapid hydrolysis of glutamine conjugates has been reported. In crickets, we found an additional unique biosynthetic pathway for glutamic acid conjugates. T. taiwanemma converted glutamine conjugates to glutamic acid conjugates by deaminating the side chain of the glutamine moiety. Considering these findings together with previous results, a possibility that FACs in these insects are results of convergent evolution can not be ruled out, but it is more likely that the ancestral insects had the glutamine conjugates and crickets and other insects developed glutamic acid conjugates in a

  2. Synthesis and characterization of fac-Re(CO)3-aspartic-N-monoacetic acid, a structural analogue of a potential new renal tracer, fac-99mTc(CO)3(ASMA).

    Science.gov (United States)

    Klenc, Jeffrey; Lipowska, Malgorzata; Taylor, Andrew T; Marzilli, Luigi G

    2012-09-01

    The reaction of an aminopolycarboxylate ligand, as partic- N - m onoacetic a cid (ASMA), with [Re(CO) 3 (H 2 O) 3 ] + was examined. The tridentate coordination of ASMA to this Re I tricarbonyl precursor yielded fac -Re(CO) 3 (ASMA) as a mixture of diastereomers. The chemistry is analogous to that of the Tc I tricarbonyl complex, which yields fac - 99m Tc(CO) 3 (ASMA) under similar conditions. The formation, structure, and isomerization of fac -Re(CO) 3 (ASMA) products were characterized by HPLC, 1 H NMR spectroscopy, and X-ray crystallography. The two major fac -Re(CO) 3 (ASMA) diastereomeric products each have a linear ONO coordination mode with two adjacent five-membered chelate rings, but they differ in the endo or exo orientation of the uncoordinated acetate group, in agreement with expectations based on previous studies. Conditions have been identified for the expedient isomerization of fac -Re(CO) 3 (ASMA) to a mixture consisting primarily of one major product. Because different isomeric species typically have different pharmacokinetic characteristics, these conditions may provide for the practical isolation of a single 99m Tc(CO) 3 (ASMA) species, thus allowing the isolation of the isomer that has optimal imaging and pharmacokinetic characteristics. This information will aid in the design of future 99m Tc radiopharmaceuticals.

  3. The Fanconi anemia proteins FAA and FAC function in different cellular compartments to protect against cross-linking agent cytotoxicity.

    Science.gov (United States)

    Kruyt, F A; Youssoufian, H

    1998-10-01

    Fanconi anemia (FA) is an autosomal recessive disease characterized by chromosomal instability, bone marrow failure, and a high risk of developing malignancies. Although the disorder is genetically heterogeneous, all FA cells are defined by their sensitivity to the apoptosis-inducing effect of cross-linking agents, such as mitomycin C (MMC). The cloned FA disease genes, FAC and FAA, encode proteins with no homology to each other or to any known protein. We generated a highly specific antibody against FAA and found the protein in both the cytoplasm and nucleus of mammalian cells. By subcellular fractionation, FAA is also associated with intracellular membranes. To identify the subcellular compartment that is relevant for FAA activity, we appended nuclear export and nuclear localization signals to the carboxy terminus of FAA and enriched its localization in either the cytoplasm or the nucleus. Nuclear localization of FAA was both necessary and sufficient to correct MMC sensitivity in FA-A cells. In addition, we found no evidence for an interaction between FAA and FAC either in vivo or in vitro. Together with a previous finding that FAC is active in the cytoplasm but not in the nucleus, our results indicate that FAA and FAC function in separate subcellular compartments. Thus, FAA and FAC, if functionally linked, are more likely to be in a linear pathway rather than form a macromolecular complex to protect against cross-linker cytotoxicity.

  4. Flow Accelerated Erosion-Corrosion (FAC) considerations for secondary side piping in the AP1000{sup R} nuclear power plant design

    Energy Technology Data Exchange (ETDEWEB)

    Vanderhoff, J. F.; Rao, G. V. [Westinghouse Electric Company LLC, 1000 Westinghouse Drive, Cranberry Township, PA 16066 (United States); Stein, A. [Shaw Power Nuclear, 1000 Technology Center Drive, Stoughton, MA 02072 (United States)

    2012-07-01

    The issue of Flow Accelerated Erosion-Corrosion (FAC) in power plant piping is a known phenomenon that has resulted in material replacements and plant accidents in operating power plants. Therefore, it is important for FAC resistance to be considered in the design of new nuclear power plants. This paper describes the design considerations related to FAC that were used to develop a safe and robust AP1000{sup R} plant secondary side piping design. The primary FAC influencing factors include: - Fluid Temperature - Pipe Geometry/layout - Fluid Chemistry - Fluid Velocity - Pipe Material Composition - Moisture Content (in steam lines) Due to the unknowns related to the relative impact of the influencing factors and the complexities of the interactions between these factors, it is difficult to accurately predict the expected wear rate in a given piping segment in a new plant. This paper provides: - a description of FAC and the factors that influence the FAC degradation rate, - an assessment of the level of FAC resistance of AP1000{sup R} secondary side system piping, - an explanation of options to increase FAC resistance and associated benefits/cost, - discussion of development of a tool for predicting FAC degradation rate in new nuclear power plants. (authors)

  5. Microstructure Evolution and Chemical Analysis on Carbon Steels and Fe-Cr-Mo Alloys after FAC Simulation Tests

    International Nuclear Information System (INIS)

    Kim, Seunghyun; Kim, Taeho; Lee, Yun Ju; Kim, Ji Hyun

    2017-01-01

    Flow-accelerated corrosion (FAC) is an environment assisted degradation of structural materials, which usually occurs in pipelines of power plants. There have been many studies to investigate the fundamental mechanism and corresponding countermeasures against FAC, and recently the carbon steels have been replaced by ASTM A 335 P22, which contains approximately 2.2 wt.% of Cr and 1 wt.% of Mo. By enhancing passivity of P22 by Cr, it is reported that FAC rate has been greatly reduced. However, while corrosion behavior of Fe-based alloys is relatively well known, their behavior under high-temperature flowing water is not well investigated. In other words, effects of Cr and its corrosion and oxidation behavior is not clearly revealed. Furthermore, it is known that Mo enhances the pitting corrosion resistance of alloys however its mechanism is not clearly investigated. Recently, replacement of Mo in alloy contents has been widely studied because of the cost of Mo. Carbon steels undergo severe environmental-assisted degradation behavior so called FAC, and as its countermeasure the carbon steel has been replaced by P22 which contains Cr and Mo. It is generally known that Cr and Mo enhances passivity of Fe-based alloys however their corrosion and oxidation behavior has not been fully investigated especially in high-temperature flowing water environments. In this study, we employed HRTEM and synchrotron XAS techniques in order to investigate detailed microstructure evolution and chemical bonding of the commercialized carbon steel and the Fe-Cr-Mo alloys. From the analysis, it is found that while carbon steels exhibit porous oxide P22 exhibit oxide structures with thin Cr-rich oxide and spinel. Therefore, carbon steel undergoes severe FAC compared to P22 however effects of Cr and Mo and their behavior in high-temperature flowing water will be investigated.

  6. ORIGINAL ARTICLES Clinical, legal and ethical implications of the ...

    African Journals Online (AJOL)

    2009-06-01

    Jun 1, 2009 ... leakage of fluid and haemorrhage under the retina and leading to localised serous ... Rita-Marié Jansen, BSocSc (Hons) Nursing, BIur, LLB, LLM, LLD (UFS) ... balance between the statutory regulation of medication and.

  7. Health On the Net Foundation

    Science.gov (United States)

    ... non-profit, non-governmental organization, accredited to the Economic and Social Council of the United Nations. For 20 years, HON has focused on the essential question of the provision of health information to ...

  8. Original Research Original Research

    African Journals Online (AJOL)

    RAGHAVENDRA

    traditional approaches. Writing is a ... ted in English classrooms of the targeted grade level to ... process approach to teach writing in six Hon ... alternative solutions and arriving at supported ... According to this approach, the writing lesson should be.

  9. New developments in medical imaging to detect breast cancer

    African Journals Online (AJOL)

    been the 'gold standard' for imaging the breast since the mid-1960s.2 In ... Breast cancer is still one of the most common cancers in women. ... Engineering, and his qualifications include a BSc (Hons) in applied mathematics and physics.

  10. Medline Plus

    Full Text Available ... to achieve this important distinction for online health information and services. Learn more about A.D.A. ... on the Net Foundation (www.hon.ch). The information provided herein should not be used during any ...

  11. 75 FR 6421 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...

    Science.gov (United States)

    2010-02-09

    ... Broadcom Corp. BTU Peabody Energy Corp. BX Blackstone Group LP. CAL Continental Airlines Inc. CF CF... Inc. HON Honeywell International Inc. JOYG Joy Global Inc. JWN Nordstrom Inc. KFT Kraft Foods Inc...

  12. RESONANCEI--Ja-nua rY

    Indian Academy of Sciences (India)

    sharing personal experiences and viewpoints on matters related to teaching and learning science. Prithvi Ramesh. BA Hons. Mathematics. 3 rd Year. St. Stephens ... all polynomials f(t) E F2 [t], where the relation tn = 1. ______ ,AAAAAA~.

  13. Preparation, characterization and biological evaluation of fac(M(CO)3)+ labeled amino carboxy ligands

    International Nuclear Information System (INIS)

    Baishya, Rinku; Halder, K.K.; Debnath, M.C.

    2010-01-01

    Full text: The objective of this study is to radiolabel various amino carboxy based chelating ligands with fac(M(CO) 3 )+ core, their physicochemical and biological characterization so that they can be used as bifunctional chelators and could be incorporated into biomolecules. Introduction: Amino acids as a class attract considerable physiological interest because of their participation in many vital processes associated with the living system. Some amino acids express in some particular organ like glutamic acid acts as excitatory neurotransmitter in mammalian brain. Histidine, methionine, tryptophan express in the tumor cell. Amino acids also play an important role for development of a new series of chelate complexes of 99m Tc that can direct the biodistribution of the radiotracer for purposes in diagnostic nuclear medicine. Various 99m Tc-amino acid chelates based on (Tc(V)O) 3 + core were reported from this laboratory some of which exhibited high renal specificity in animals. The structural requirements favouring this biological behaviour could be the oxotechnetium glycine sequence (TcO-NH-CH 2 -COOH) resembling the -CO-glycine sequence of hippurate. In recent years with the development of organometallic chemistry of technetium and rhenium for biological application intensive efforts have been executed on designing of the bifunctional chelator for effective coordination to (M(CO) 3 )+ core. The suitability and stability of the metal carbonyl core has given rise to a new platform for the preparation of the metal complexes of biologically active peptide in macroscopic quantity using the solid phase synthetic approach. Materials and Methods: We chelated different amino carboxy based ligands with ( 99m Tc(CO) 3 )+ and (Re(CO) 3 )+ core. The choice of amino acid was made by taking representative members from various groupings such as mono amino mono carboxylate, mono amino poly carboxylate, poly amino mono carboxylate and sulfur containing amino carboxylates. The

  14. The United States Strategy in East Asia-Pacific-Implications for Australia’s Defenses

    Science.gov (United States)

    1996-01-01

    Mohamed Najib bin Tun Abdul Razak , "Towards Cooperative Security and Regional Stability, the Malaysian View." The Army and the Future. Ed. David Horner...repair and maintenance of warships on a commercial basis. See The Hon. Datuk Seri Mohamed Najib bin Tun Abdul Razak , 132. Times says that Jakarta...Cambridge University Press, 1965. The Hon. Datuk Seri Mohamed Najib bin Tun Abdul Razak . "Towards Cooperative Security and Regional Stability: The

  15. Fluorescent protein pair emit intracellular FRET signal suitable for FACS screening

    International Nuclear Information System (INIS)

    Johansson, Daniel X.; Brismar, Hjalmar; Persson, Mats A.A.

    2007-01-01

    The fluorescent proteins ECFP and HcRed were shown to give an easily resolved FRET-signal when expressed as a fusion inside mammalian cells. HeLa-tat cells expressing ECFP, pHcRed, or the fusion protein pHcRed-ECFP were analyzed by flow cytometry after excitation of ECFP. Cells expressing HcRed-ECFP, or ECFP and HcRed, were mixed and FACS-sorted for FRET positive cells: HcRed-ECFP cells were greatly enriched (72 times). Next, cloned human antibodies were fused with ECFP and expressed anchored to the ER membrane. Their cognate antigens (HIV-1 gp120 or gp41) were fused to HcRed and co-expressed in the ER. An increase of 13.5 ± 1.5% (mean ± SEM) and 8.0 ± 0.7% in ECFP fluorescence for the specific antibodies reacting with gp120 or gp41, respectively, was noted after photobleaching. A positive control (HcRed-ECFP) gave a 14.8 ± 2.6% increase. Surprisingly, the unspecific antibody (anti-TT) showed 12.1 ± 1.1% increase, possibly because overexpression in the limited ER compartment gave false FRET signals

  16. INVESTIGATION OF THE HUMIDITY EFFECT ON THE FAC-IR-300 IONIZATION CHAMBER RESPONSE.

    Science.gov (United States)

    Mohammadi, Seyed Mostafa; Tavakoli-Anbaran, Hossein

    2018-02-01

    The free-air ionization chamber is communicating with the ambient air, therefore, the atmospheric parameters such as temperature, pressure and humidity effect on the ionization chamber performance. The free-air ionization chamber, entitled as FAC-IR-300, that design at the Atomic Energy Organization of Iran, AEOI, is required the atmospheric correction factors for correct the chamber reading. In this article, the effect of humidity on the ionization chamber response was investigated. For this reason, was introduced the humidity correction factor, kh. In this article, the Monte Carlo simulation was used to determine the kh factor. The simulation results show in relative humidities between 30% to 80%, the kh factor is equal 0.9970 at 20°C and 0.9975 at 22°C. From the simulation results, at low energy the energy dependence of the kh factor is significant and with increasing energy this dependence is negligible. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  17. Engineering a promiscuous pyrrolysyl-tRNA synthetase by a high throughput FACS screen

    KAUST Repository

    Hohl, Adrian

    2017-12-06

    The Pyrrolysyl-tRNA synthetase (PylRS) and its cognate tRNAPyl are used to facilitate the incorporation of non-canonical amino acids (ncAAs) into the genetic code of bacterial and eukaryotic cells by orthogonally reassigning the amber codon. Currently, the incorporation of new ncAAs requires a cumbersome engineering process composed of several positive and negative selection rounds to select the appropriate PylRS/tRNAPyl pair. Our fast and sensitive engineering approach required only a single FACS selection round to identify 110 orthogonal PylRS variants for the aminoacylation of 20 ncAAs. Pocket-substrate relationship from these variants led to the design of a highly promiscuous PylRS (HpRS), which catalyzed the aminoacylation of 31 structurally diverse lysine derivatives bearing clickable, fluorinated, fluorescent, and biotinylated entities. The high speed and sensitivity of our approach provides a competitive alternative to existing screening methodologies, and delivers insights into the complex PylRS-substrate interactions to facilitate the generation of additional promiscuous variants.

  18. FACS-Assisted CRISPR-Cas9 Genome Editing Facilitates Parkinson's Disease Modeling

    Directory of Open Access Journals (Sweden)

    Jonathan Arias-Fuenzalida

    2017-11-01

    Full Text Available Genome editing and human induced pluripotent stem cells hold great promise for the development of isogenic disease models and the correction of disease-associated mutations for isogenic tissue therapy. CRISPR-Cas9 has emerged as a versatile and simple tool for engineering human cells for such purposes. However, the current protocols to derive genome-edited lines require the screening of a great number of clones to obtain one free of random integration or on-locus non-homologous end joining (NHEJ-containing alleles. Here, we describe an efficient method to derive biallelic genome-edited populations by the use of fluorescent markers. We call this technique FACS-assisted CRISPR-Cas9 editing (FACE. FACE allows the derivation of correctly edited polyclones carrying a positive selection fluorescent module and the exclusion of non-edited, random integrations and on-target allele NHEJ-containing cells. We derived a set of isogenic lines containing Parkinson's-disease-associated mutations in α-synuclein and present their comparative phenotypes.

  19. Fuel Accident Condition Simulator (FACS) Furnace for Post-Irradiation Heating Tests of VHTR Fuel Compacts

    Energy Technology Data Exchange (ETDEWEB)

    Paul A Demkowicz; Paul Demkowicz; David V Laug

    2010-10-01

    Abstract –Fuel irradiation testing and post-irradiation examination are currently in progress as part of the Next Generation Nuclear Plant Fuels Development and Qualification Program. The PIE campaign will include extensive accident testing of irradiated very high temperature reactor fuel compacts to verify fission product retention characteristics at high temperatures. This work will be carried out at both the Idaho National Laboratory (INL) and the Oak Ridge National Laboratory, beginning with accident tests on irradiated fuel from the AGR-1 experiment in 2010. A new furnace system has been designed, built, and tested at INL to perform high temperature accident tests. The Fuel Accident Condition Simulator furnace system is designed to heat fuel specimens at temperatures up to 2000°C in helium while monitoring the release of volatile fission metals (e.g. Cs, Ag, Sr, Eu, and I) and fission gases (Kr, Xe). Fission gases released from the fuel to the sweep gas are monitored in real time using dual cryogenic traps fitted with high purity germanium detectors. Condensable fission products are collected on a plate attached to a water-cooled cold finger that can be exchanged periodically without interrupting the test. Analysis of fission products on the condensation plates involves dry gamma counting followed by chemical analysis of selected isotopes. This paper will describe design and operational details of the Fuel Accident Condition Simulator (FACS) furnace system, as well as preliminary system calibration results.

  20. Engineering a promiscuous pyrrolysyl-tRNA synthetase by a high throughput FACS screen

    KAUST Repository

    Hohl, Adrian; Karan, Ram; Akal, Anstassja; Renn, Dominik; Liu, Xuechao; Dharamarajnadar, Alaguraj; Ghoprade, Seema Arun; Groll, Michael; Rueping, Magnus; Eppinger, Jö rg

    2017-01-01

    The Pyrrolysyl-tRNA synthetase (PylRS) and its cognate tRNAPyl are used to facilitate the incorporation of non-canonical amino acids (ncAAs) into the genetic code of bacterial and eukaryotic cells by orthogonally reassigning the amber codon. Currently, the incorporation of new ncAAs requires a cumbersome engineering process composed of several positive and negative selection rounds to select the appropriate PylRS/tRNAPyl pair. Our fast and sensitive engineering approach required only a single FACS selection round to identify 110 orthogonal PylRS variants for the aminoacylation of 20 ncAAs. Pocket-substrate relationship from these variants led to the design of a highly promiscuous PylRS (HpRS), which catalyzed the aminoacylation of 31 structurally diverse lysine derivatives bearing clickable, fluorinated, fluorescent, and biotinylated entities. The high speed and sensitivity of our approach provides a competitive alternative to existing screening methodologies, and delivers insights into the complex PylRS-substrate interactions to facilitate the generation of additional promiscuous variants.

  1. Apportioning bacterial carbon source utilization in soil using 14 C isotope analysis of FISH-targeted bacterial populations sorted by fluorescence activated cell sorting (FACS): 14 C-FISH-FACS.

    Science.gov (United States)

    Gougoulias, Christos; Meade, Andrew; Shaw, Liz J

    2018-02-19

    An unresolved need in microbial ecology is methodology to enable quantitative analysis of in situ microbial substrate carbon use at the population level. Here, we evaluated if a novel combination of radiocarbon-labelled substrate tracing, fluorescence in situ hybridisation (FISH) and fluorescence-activated cell sorting (FACS) to sort the FISH-targeted population for quantification of incorporated radioactivity ( 14 C-FISH-FACS) can address this need. Our test scenario used FISH probe PSE1284 targeting Pseudomonas spp. (and some Burkholderia spp.) and salicylic acid added to rhizosphere soil. We examined salicylic acid- 14 C fate (mineralized, cell-incorporated, extractable and non-extractable) and mass balance (0-24 h) and show that the PSE1284 population captured ∼ 50% of the Nycodenz extracted biomass 14 C. Analysis of the taxonomic distribution of the salicylic acid biodegradation trait suggested that PSE1284 population success was not due to conservation of this trait but due to competitiveness for the added carbon. Adding 50KBq of 14 C sample -1 enabled detection of 14 C in the sorted population at ∼ 60-600 times background; a sensitivity which demonstrates potential extension to analysis of rarer/less active populations. Given its sensitivity and compatibility with obtaining a C mass balance, 14 C-FISH-FACS allows quantitative dissection of C flow within the microbial biomass that has hitherto not been achieved. © 2018 Society for Applied Microbiology and John Wiley & Sons Ltd.

  2. Investigation of electron-loss and photon scattering correction factors for FAC-IR-300 ionization chamber

    Science.gov (United States)

    Mohammadi, S. M.; Tavakoli-Anbaran, H.; Zeinali, H. Z.

    2017-02-01

    The parallel-plate free-air ionization chamber termed FAC-IR-300 was designed at the Atomic Energy Organization of Iran, AEOI. This chamber is used for low and medium X-ray dosimetry on the primary standard level. In order to evaluate the air-kerma, some correction factors such as electron-loss correction factor (ke) and photon scattering correction factor (ksc) are needed. ke factor corrects the charge loss from the collecting volume and ksc factor corrects the scattering of photons into collecting volume. In this work ke and ksc were estimated by Monte Carlo simulation. These correction factors are calculated for mono-energy photon. As a result of the simulation data, the ke and ksc values for FAC-IR-300 ionization chamber are 1.0704 and 0.9982, respectively.

  3. Investigation of electron-loss and photon scattering correction factors for FAC-IR-300 ionization chamber

    International Nuclear Information System (INIS)

    Mohammadi, S.M.; Tavakoli-Anbaran, H.; Zeinali, H.Z.

    2017-01-01

    The parallel-plate free-air ionization chamber termed FAC-IR-300 was designed at the Atomic Energy Organization of Iran, AEOI. This chamber is used for low and medium X-ray dosimetry on the primary standard level. In order to evaluate the air-kerma, some correction factors such as electron-loss correction factor (k e ) and photon scattering correction factor (k sc ) are needed. k e factor corrects the charge loss from the collecting volume and k sc factor corrects the scattering of photons into collecting volume. In this work k e and k sc were estimated by Monte Carlo simulation. These correction factors are calculated for mono-energy photon. As a result of the simulation data, the k e and k sc values for FAC-IR-300 ionization chamber are 1.0704 and 0.9982, respectively.

  4. Pain elicited by the Cold Pressor Test: A gender-comparative FACS coding study of spontaneous, faked and inhibited expressions.

    OpenAIRE

    Gil, Luisa; De Sousa, Cristina; Baunninger-Huber, Eva; Schiestl, Cathrin; Toussaint, Kyra; Gruber, Verena; Oliveira, Armando Monica; Duarte, Ana Catarina

    2012-01-01

    Evolutionary theories of pain have conjectured a better ability of males to control their facial expressions of pain, and of females to express and communicate emotions through the face. The present study involved 24 participants (12 men; 12 women). Pain was induced via the Cold Pressor Test (CPT), and three expressive contexts (spontaneous, faked an inhibited) were created through instructions. Elicited pain expressions were FACS coded and frequency, indices were derived for the observed Act...

  5. Towards and FVE-FAC Method for Determining Thermocapillary Effects on Weld Pool Shape

    Science.gov (United States)

    Canright, David; Henson, Van Emden

    1996-01-01

    Several practical materials processes, e.g., welding, float-zone purification, and Czochralski crystal growth, involve a pool of molten metal with a free surface, with strong temperature gradients along the surface. In some cases, the resulting thermocapillary flow is vigorous enough to convect heat toward the edges of the pool, increasing the driving force in a sort of positive feedback. In this work we examine this mechanism and its effect on the solid-liquid interface through a model problem: a half space of pure substance with concentrated axisymmetric surface heating, where surface tension is strong enough to keep the liquid free surface flat. The numerical method proposed for this problem utilizes a finite volume element (FVE) discretization in cylindrical coordinates. Because of the axisymmetric nature of the model problem, the control volumes used are torroidal prisms, formed by taking a polygonal cross-section in the (r, z) plane and sweeping it completely around the z-axis. Conservation of energy (in the solid), and conservation of energy, momentum, and mass (in the liquid) are enforced globally by integrating these quantities and enforcing conservation over each control volume. Judicious application of the Divergence Theorem and Stokes' Theorem, combined with a Crank-Nicolson time-stepping scheme leads to an implicit algebraic system to be solved at each time step. It is known that near the boundary of the pool, that is, near the solid-liquid interface, the full conduction-convection solution will require extremely fine length scales to resolve the physical behavior of the system. Furthermore, this boundary moves as a function of time. Accordingly, we develop the foundation of an adaptive refinement scheme based on the principles of Fast Adaptive Composite Grid methods (FAC). Implementation of the method and numerical results will appear in a later report.

  6. The Fuel Accident Condition Simulator (FACS) furnace system for high temperature performance testing of VHTR fuel

    Energy Technology Data Exchange (ETDEWEB)

    Demkowicz, Paul A., E-mail: paul.demkowicz@inl.gov [Idaho National Laboratory, 2525 Fremont Avenue, MS 3860, Idaho Falls, ID 83415-3860 (United States); Laug, David V.; Scates, Dawn M.; Reber, Edward L.; Roybal, Lyle G.; Walter, John B.; Harp, Jason M. [Idaho National Laboratory, 2525 Fremont Avenue, MS 3860, Idaho Falls, ID 83415-3860 (United States); Morris, Robert N. [Oak Ridge National Laboratory, 1 Bethel Valley Road, Oak Ridge, TN 37831 (United States)

    2012-10-15

    Highlights: Black-Right-Pointing-Pointer A system has been developed for safety testing of irradiated coated particle fuel. Black-Right-Pointing-Pointer FACS system is designed to facilitate remote operation in a shielded hot cell. Black-Right-Pointing-Pointer System will measure release of fission gases and condensable fission products. Black-Right-Pointing-Pointer Fuel performance can be evaluated at temperatures as high as 2000 Degree-Sign C in flowing helium. - Abstract: The AGR-1 irradiation of TRISO-coated particle fuel specimens was recently completed and represents the most successful such irradiation in US history, reaching peak burnups of greater than 19% FIMA with zero failures out of 300,000 particles. An extensive post-irradiation examination (PIE) campaign will be conducted on the AGR-1 fuel in order to characterize the irradiated fuel properties, assess the in-pile fuel performance in terms of coating integrity and fission metals release, and determine the fission product retention behavior during high temperature safety testing. A new furnace system has been designed, built, and tested to perform high temperature accident tests. The Fuel Accident Condition Simulator furnace system is designed to heat fuel specimens at temperatures up to 2000 Degree-Sign C in helium while monitoring the release of volatile fission metals (e.g. Cs, Ag, Sr, and Eu), iodine, and fission gases (Kr, Xe). Fission gases released from the fuel to the sweep gas are monitored in real time using dual cryogenic traps fitted with high purity germanium detectors. Condensable fission products are collected on a plate attached to a water-cooled cold finger that can be exchanged periodically without interrupting the test. Analysis of fission products on the condensation plates involves dry gamma counting followed by chemical analysis of selected isotopes. This paper will describe design and operational details of the Fuel Accident Condition Simulator furnace system and the associated

  7. National Status and Trends, Benthic Surveillance Project Fluorescent Aromatic Compounds (FAC) Data, 1984-1991, National Centers for Coastal Ocean Science

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Status and Trends (NSandT) Benthic Surveillance Fluorescent Aromatic Compounds (FAC) file reports the trace concentrations of Fluorescent Aromatic...

  8. Comparison of Docetaxel, Doxorubicin and Cyclophosphamide (TAC with 5-Fluorouracil, Doxorubicin and Cyclophosphamide (FAC Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer: A Phase III Clinical Trial

    Directory of Open Access Journals (Sweden)

    Mohammad Mohammadianpanah

    2011-04-01

    Full Text Available Background: The present study aimed to compare the rates of complete clinical and pathologic response to docetaxel, doxorubicin and cyclophosphamide (TAC vs. 5-fluorouracil, doxorubicin and cyclophosphamide (FAC as neoadjuvant chemotherapy in women with locally advanced breast cancer.Methods: One hundred women with pathologically confirmed newly diagnosed locally advanced (T3-T4 or N2-N3 breast cancer were randomly assigned to receive a median of four cycles of either 5-fluorouracil (600 mg/m2, doxorubicin (60 mg/m2 and cyclophosphamide (600 mg/m2 every three weeks or docetaxel (75 mg/m2, doxorubicin (50 mg/m2 and cyclophosphamide (500 mg/m2 every three weeks followed by modified radical mastectomy. Complete clinical and pathologic response rates and toxicity were the primary and secondary outcome measures of the study. Results: Median age for all patients was 43.4 years (range 25-63 years. Patients in the TAC arm achieved a higher clinical (16% response rate than those in the FAC arm (4%, P=0.046. The pathologic response rate was also higher in the TAC arm compared to the FAC arm [TAC (20% vs. FAC (6%, P=0.037]. Estrogen receptor-negative status correlated with a higher clinical [TAC (19% vs. FAC (4%, P=0.032]and pathologic [TAC (23% vs. FAC (4%, P=0.011] response rate in both arms. All patients generally tolerated treatment well, and treatment-related toxicities were manageable. Conclusion: Combined treatment with TAC led to higher rates of complete clinical and pathologic response with acceptable toxicity compared to FAC in patients with locally advanced breast cancer. However, further follow-up is needed to translate this response into improvements in survival.

  9. 18F-FAC PET selectively images hepatic infiltrating CD4 and CD8 T cells in a mouse model of autoimmune hepatitis.

    Science.gov (United States)

    Salas, Jessica R; Chen, Bao Ying; Wong, Alicia; Cheng, Donghui; Van Arnam, John S; Witte, Owen N; Clark, Peter M

    2018-04-26

    Immune cell-mediated attack on the liver is a defining feature of autoimmune hepatitis and hepatic allograft rejection. Despite an assortment of diagnostic tools, invasive biopsies remain the only method for identifying immune cells in the liver. We evaluated whether PET imaging with radiotracers that quantify immune activation ( 18 F-FDG and 18 F-FAC) and hepatocyte biology ( 18 F-DFA) can visualize and quantify hepatic infiltrating immune cells and hepatocyte inflammation, respectively, in a preclinical model of autoimmune hepatitis. Methods: Mice treated with Concanavalin A (ConA) to induce a model of autoimmune hepatitis or vehicle were imaged with 18 F-FDG, 18 F-FAC, and 18 F-DFA PET. Immunohistochemistry, digital autoradiography, and ex vivo accumulation assays were used to localize areas of altered radiotracer accumulation in the liver. For comparison, mice treated with an adenovirus to induce a viral hepatitis or vehicle were imaged with 18 F-FDG, 18 F-FAC, and 18 F-DFA PET. 18 F-FAC PET was performed on mice treated with ConA, and vehicle or dexamethasone. Biopsy samples of patients suffering from autoimmune hepatitis were immunostained for deoxycytidine kinase (dCK). Results: Hepatic accumulation of 18 F-FDG and 18 F-FAC was 173% and 61% higher, respectively, and hepatic accumulation of 18 F-DFA was 41% lower in a mouse model of autoimmune hepatitis compared to control mice. Increased hepatic 18 F-FDG accumulation was localized to infiltrating leukocytes and inflamed sinusoidal endothelial cells, increased hepatic 18 F-FAC accumulation was concentrated in infiltrating CD4 and CD8 cells, and decreased hepatic 18 F-DFA accumulation was apparent in hepatocytes throughout the liver. In contrast, viral hepatitis increased hepatic 18 F-FDG accumulation by 109% and decreased hepatic 18 F-DFA accumulation by 20% but had no effect on hepatic 18 F-FAC accumulation (non-significant 2% decrease). 18 F-FAC PET provided a non-invasive biomarker of the efficacy of

  10. Rapid isolation of antibody from a synthetic human antibody library by repeated fluorescence-activated cell sorting (FACS.

    Directory of Open Access Journals (Sweden)

    Sung Sun Yim

    Full Text Available Antibodies and their derivatives are the most important agents in therapeutics and diagnostics. Even after the significant progress in the technology for antibody screening from huge libraries, it takes a long time to isolate an antibody, which prevents a prompt action against the spread of a disease. Here, we report a new strategy for isolating desired antibodies from a combinatorial library in one day by repeated fluorescence-activated cell sorting (FACS. First, we constructed a library of synthetic human antibody in which single-chain variable fragment (scFv was expressed in the periplasm of Escherichia coli. After labeling the cells with fluorescent antigen probes, the highly fluorescent cells were sorted by using a high-speed cell sorter, and these cells were reused without regeneration in the next round of sorting. After repeating this sorting, the positive clones were completely enriched in several hours. Thus, we screened the library against three viral antigens, including the H1N1 influenza virus, Hepatitis B virus, and Foot-and-mouth disease virus. Finally, the potential antibody candidates, which show K(D values between 10 and 100 nM against the target antigens, could be successfully isolated even though the library was relatively small (∼ 10(6. These results show that repeated FACS screening without regeneration of the sorted cells can be a powerful method when a rapid response to a spreading disease is required.

  11. Asymmetric distribution of the ionospheric electric potential in the opposite hemispheres as inferred from the SuperDARN observations and FAC-based convection model

    DEFF Research Database (Denmark)

    Lukianova, R.; Hanuise, C.; Christiansen, Freddy

    2008-01-01

    We compare the SuperDARN convection patterns with the predictions of a new numerical model of the global distribution of ionospheric electric potentials. The model utilizes high-precision statistical maps of field-aligned currents (FAC) derived from measurements made by polar-orbiting low-altitud...

  12. An improved flow cytometric method using FACS lysing solution for measurement of ZAP-70 expression in B-cell chronic lymphocytic leukemia

    NARCIS (Netherlands)

    Bekkema, Roelof; Tadema, Afke; Daenen, Simon M. G. J.; Kluin-Nelemans, Hanneke C.; Mulder, Andre B.

    Background: B-cell expression of ZAP-70, normally expressed in T and NK cells, correlates with poor prognosis in B-CLL. Poor discrimination between ZAP-70 positive and negative cells hampers routine application of flow cytometry. We examined the usefulness of FACS Lysing Solution. Methods: ZAP-70

  13. Efficient genome editing by FACS enrichment of paired D10A Cas9 nickases coupled with fluorescent proteins.

    Science.gov (United States)

    Gopalappa, Ramu; Song, Myungjae; Chandrasekaran, Arun Pandian; Das, Soumyadip; Haq, Saba; Koh, Hyun Chul; Ramakrishna, Suresh

    2018-05-31

    Targeted genome editing by clustered regularly interspaced short palindromic repeats (CRISPR-Cas9) raised concerns over off-target effects. The use of double-nicking strategy using paired Cas9 nickase has been developed to minimize off-target effects. However, it was reported that the efficiency of paired nickases were comparable or lower than that of either corresponding nuclease alone. Recently, we conducted a systematic comparison of the efficiencies of several paired Cas9 with their corresponding Cas9 nucleases and showed that paired D10A Cas9 nickases are sometimes more efficient than individual nucleases for gene disruption. However, sometimes the designed paired Cas9 nickases exhibited significantly lower mutation frequencies than nucleases, hampering the generation of cells containing paired Cas9 nickase-induced mutations. Here we implemented IRES peptide-conjugation of fluorescent protein to Cas9 nickase and subjected for fluorescence-activated cell sorting. The sorted cell populations are highly enriched with cells containing paired Cas9 nickase-induced mutations, by a factor of up to 40-fold as compared with the unsorted population. Furthermore, gene-disrupted single cell clones using paired nickases followed by FACS sorting strategy were generated highly efficiently, without compromising with its low off-target effects. We envision that our fluorescent protein coupled paired nickase-mediated gene disruption, facilitating efficient and highly specific genome editing in medical research.

  14. A mammalian cell based FACS-panning platform for the selection of HIV-1 envelopes for vaccine development.

    Directory of Open Access Journals (Sweden)

    Tim-Henrik Bruun

    Full Text Available An increasing number of broadly neutralizing monoclonal antibodies (bnMAb against the HIV-1 envelope (Env protein has been discovered recently. Despite this progress, vaccination efforts with the aim to re-elicit bnMAbs that provide protective immunity have failed so far. Herein, we describe the development of a mammalian cell based FACS-panning method in which bnMAbs are used as tools to select surface-exposed envelope variants according to their binding affinity. For that purpose, an HIV-1 derived lentiviral vector was developed to infect HEK293T cells at low multiplicity of infection (MOI in order to link Env phenotype and genotype. For proof of principle, a gp145 Env model-library was established in which the complete V3 domain was substituted by five strain specific V3 loop sequences with known binding affinities to nMAb 447-52D, respectively. Env genes were recovered from selected cells by PCR, subcloned into a lentiviral vector (i to determine and quantify the enrichment nMAb binders and (ii to generate a new batch of transduction competent particles. After 2 selection cycles the Env variant with highest affinity was enriched 20-fold and represented 80% of the remaining Env population. Exploiting the recently described bnMAbs, this procedure might prove useful in selecting Env proteins from large Env libraries with the potential to elicit bnMAbs when used as vaccine candidates.

  15. The Synthesis and X-ray Structural Characterization of mer and fac isomers of the Technetium(I) Nitrosyl Complex [TcCl(2)(NO)(PNPpr)].

    Science.gov (United States)

    Nicholson, T L; Mahmood, A; Refosco, F; Tisato, F; Müller, P; Jones, A G

    2009-08-01

    The nitrosyl complex H[TcNOCl(4)] reacts with the tridentate ligand bis[(2-diphenylphosphino)propyl]amine (PNPpr) to yield a mixture of the mer or fac isomers of [TcCl(2)(NO)(PNPpr)]. In acetonitrile, where the ligand is freely soluble, reaction occurs at room temperature to yield mostly the mer isomer with the linear nitrosyl ligand cis to the amine ligand; and the phosphine ligands arranged in a mutually trans orientation. The reaction in methanol requires reflux to dissolve the lipophilic ligand and generates the fac isomer of [TcCl2(NO)(PNPpr)] as the major product, with the tridentate ligand in a facial arrangement, leaving the chlorides and nitrosyl ligand in the remaining facial sites. The steric bulk of the tridentate ligand's diphenylphophino- moieties results in a significant distortion from octahedral geometry, with the P-Tc-P bond angle expanded to 99.48(4)°. The infrared spectra display absorptions from these nitrosyl ligands in the 1700 and 1800 cm(-1) regions for the fac and mer isomers respectively. The ESI(+) mass spectra each display the parent ion at 647 m/z.

  16. Comparative analysis of circulating endothelial progenitor cells in age-related macular degeneration patients using automated rare cell analysis (ARCA and fluorescence activated cell sorting (FACS.

    Directory of Open Access Journals (Sweden)

    Emil Anthony T Say

    Full Text Available BACKGROUND: Patients with age-related macular degeneration (ARMD begin with non-neovascular (NNV phenotypes usually associated with good vision. Approximately 20% of NNV-ARMD patients will convert to vision debilitating neovascular (NV ARMD, but precise timing of this event is unknown. Developing a clinical test predicting impending conversion to NV-ARMD is necessary to prevent vision loss. Endothelial progenitor cells (EPCs, defined as CD34(+VEGR2(+ using traditional fluorescence activated cell sorting (FACS, are rare cell populations known to be elevated in patients with NV-ARMD compared to NNV-ARMD. FACS has high inter-observer variability and subjectivity when measuring rare cell populations precluding development into a diagnostic test. We hypothesized that automated rare cell analysis (ARCA, a validated and FDA-approved technology for reproducible rare cell identification, can enumerate EPCs in ARMD patients more reliably. This pilot study serves as the first step in developing methods for reproducibly predicting ARMD phenotype conversion. METHODS: We obtained peripheral venous blood samples in 23 subjects with NNV-ARMD or treatment naïve NV-ARMD. Strict criteria were used to exclude subjects with known angiogenic diseases to minimize confounding results. Blood samples were analyzed in masked fashion in two separate laboratories. EPCs were independently enumerated using ARCA and FACS within 24 hours of blood sample collection, and p<0.2 was considered indicative of a trend for this proof of concept study, while statistical significance was established at 0.05. RESULTS: We measured levels of CD34(+VEGFR2(+ EPCs suggestive of a trend with higher values in patients with NV compared to NNV-ARMD (p = 0.17 using ARCA. Interestingly, CD34(+VEGR2(+ EPC analysis using FACS did not produce similar results (p = 0.94. CONCLUSIONS: CD34(+VEGR2(+ may have predictive value for EPC enumeration in future ARCA studies. EPC measurements in a small sample

  17. Comparative analysis of circulating endothelial progenitor cells in age-related macular degeneration patients using automated rare cell analysis (ARCA) and fluorescence activated cell sorting (FACS).

    Science.gov (United States)

    Say, Emil Anthony T; Melamud, Alex; Esserman, Denise Ann; Povsic, Thomas J; Chavala, Sai H

    2013-01-01

    Patients with age-related macular degeneration (ARMD) begin with non-neovascular (NNV) phenotypes usually associated with good vision. Approximately 20% of NNV-ARMD patients will convert to vision debilitating neovascular (NV) ARMD, but precise timing of this event is unknown. Developing a clinical test predicting impending conversion to NV-ARMD is necessary to prevent vision loss. Endothelial progenitor cells (EPCs), defined as CD34(+)VEGR2(+) using traditional fluorescence activated cell sorting (FACS), are rare cell populations known to be elevated in patients with NV-ARMD compared to NNV-ARMD. FACS has high inter-observer variability and subjectivity when measuring rare cell populations precluding development into a diagnostic test. We hypothesized that automated rare cell analysis (ARCA), a validated and FDA-approved technology for reproducible rare cell identification, can enumerate EPCs in ARMD patients more reliably. This pilot study serves as the first step in developing methods for reproducibly predicting ARMD phenotype conversion. We obtained peripheral venous blood samples in 23 subjects with NNV-ARMD or treatment naïve NV-ARMD. Strict criteria were used to exclude subjects with known angiogenic diseases to minimize confounding results. Blood samples were analyzed in masked fashion in two separate laboratories. EPCs were independently enumerated using ARCA and FACS within 24 hours of blood sample collection, and ptrend for this proof of concept study, while statistical significance was established at 0.05. We measured levels of CD34(+)VEGFR2(+) EPCs suggestive of a trend with higher values in patients with NV compared to NNV-ARMD (p = 0.17) using ARCA. Interestingly, CD34(+)VEGR2(+) EPC analysis using FACS did not produce similar results (p = 0.94). CD34(+)VEGR2(+) may have predictive value for EPC enumeration in future ARCA studies. EPC measurements in a small sample size were suggestive of a trend in ARMD using ARCA but not FACS. ARCA could be a

  18. Injection of nano-particles in mitigating flow accelerated corrosion (FAC) damage in the secondary system of nuclear power plants (NPPs)

    International Nuclear Information System (INIS)

    Lim, Dong Seok; Ku, Hee Kwon; Cho, Jae Seon

    2015-01-01

    NPPs produces electric energy through phase transition of water. According to this, a piping, which is flow path, integrity is essential for safety functions. Erosion, FAC and fittings are corrosion failure mechanism by increasing service life. Especially, there are 10-kilometers of piping in secondary systems. It needs to estimate FAC and apply periodic management. Iron oxides produced by FAC cause power reduction and Loss Of Coolant Accident (LOCA) will be occurred through the continued piping wall thinning. In this study, corrosion rate of pipe materials with carbon steel(SA106.Gr.B) and low-alloy steel (SA335.P22) was evaluated for pipe configuration and dissolved oxygen concentration on 150 °C, pH 9.5∼10.0 and flow velocity of 5m/s. Temperature of 150°C is well known that causes high FAC rate and pH consider a NPPs in-service condition. Further corrosion rate test was performed to develop FAC reduction technology through Pt-nanoparticle injection. In this study, corrosion rate is evaluated by weight depletion method. The results of material impact assessment show that corrosion rate of carbon steel is more higher than that of low-alloy steel because of Cr content. And also, the results of pipe configuration test show that case with 90° elbow had maximum wall thinning than with 180° horizontal pipe. The dissolved oxygen concentration test shows that low oxygen condition, ≤5 ppb, had high corrosion rate compared to normal condition and the corrosion rate decreased 50% at Pt-nanoparticle injection test on maximum corrosion rate condition compared to maximum wall thinning condition without Pt-nanoparticle injection. In this study, samples provided by each test case had analyzed through SEM-EDX (Scanning Electron Microscopy-Energy Dispersive X-ray Spectroscopy). Behavior evaluation for oxide film was performed and Electrochemical corrosion potential (ECP) was measured for electrochemistry evaluation. To apply Pt-nanoparticle injection technology on nuclear

  19. Co-Targeting Prostate Cancer Epithelium and Bone Stroma by Human Osteonectin-Promoter-Mediated Suicide Gene Therapy Effectively Inhibits Androgen-Independent Prostate Cancer Growth.

    Directory of Open Access Journals (Sweden)

    Shian-Ying Sung

    Full Text Available Stromal-epithelial interaction has been shown to promote local tumor growth and distant metastasis. We sought to create a promising gene therapy approach that co-targets cancer and its supporting stromal cells for combating castration-resistant prostate tumors. Herein, we demonstrated that human osteonectin is overexpressed in the prostate cancer epithelium and tumor stroma in comparison with their normal counterpart. We designed a novel human osteonectin promoter (hON-522E containing positive transcriptional regulatory elements identified in both the promoter and exon 1 region of the human osteonectin gene. In vitro reporter assays revealed that the hON-522E promoter is highly active in androgen receptor negative and metastatic prostate cancer and bone stromal cells compared to androgen receptor-positive prostate cancer cells. Moreover, in vivo prostate-tumor-promoting activity of the hON-522E promoter was confirmed by intravenous administration of an adenoviral vector containing the hON-522E promoter-driven luciferase gene (Ad-522E-Luc into mice bearing orthotopic human prostate tumor xenografts. In addition, an adenoviral vector with the hON-522E-promoter-driven herpes simplex virus thymidine kinase gene (Ad-522E-TK was highly effective against the growth of androgen-independent human prostate cancer PC3M and bone stromal cell line in vitro and in pre-established PC3M tumors in vivo upon addition of the prodrug ganciclovir. Because of the heterogeneity of human prostate tumors, hON-522E promoter-mediated gene therapy has the potential for the treatment of hormone refractory and bone metastatic prostate cancers.

  20. Department of Zoology, Fac

    African Journals Online (AJOL)

    USER

    2015-01-07

    Jan 7, 2015 ... flowers located between the trees) which is drier forms a ... (moist and deciduous forest); and Ilorin is in the northern ..... Washington D. C. (Conservation. International) ... Amphibians of Eastern and Central. North America, 3 rd.

  1. Whistleblower Issues in the Nuclear Industry. Hearing before the Subcommittee on Clean Air and Nuclear Regulation of the Committee on Environment and Public Works, United States Senate, One Hundred Third Congress, First Session, July 15, 1993

    International Nuclear Information System (INIS)

    Anon.

    1994-01-01

    This hearing concerns NRC's treatment of whistleblowers in the nuclear industry. Whistleblowers are defined as people who inform the NRC of nuclear safety concerns, or people who allege that they were intimidated and harassed by their employer because they raised safety issues. Testimony from the following is included in this volume: P. Blanch; A.W. Dahlbergy III CEO Georgia Power Co.; J. Goldberg, President, Nuclear Division, Florida Power and Light; A. Mosbaugh; Hon. Ivan Selin, NRC; Hon. David C. Williams, Inspector General, NRC

  2. Defense Science Board (DSB) Summer Study Report on Strategic Surprise

    Science.gov (United States)

    2015-07-01

    modeling  and  simulation capabilities and test facilities.  Recommendation 15  Leveraging the Internet of Things  Department of Defense should create a...Manferdelli      Intel  Dr. Joseph  Markowitz       Private Consultant  Dr. Mark Maybury      MITRE  Hon. James Miller      Private Consultant  Hon. Judith

  3. Syntheses and multi-NMR study of fac- and mer-OsO(3)F(2)(NCCH(3)) and the X-ray crystal structure (n = 2) and Raman spectrum (n = 0) of fac-OsO(3)F(2)(NCCH(3)).nCH(3)CN.

    Science.gov (United States)

    Hughes, Michael J; Gerken, Michael; Mercier, Hélène P A; Schrobilgen, Gary J

    2010-06-07

    Dissolution of the infinite chain polymer, (OsO(3)F(2))(infinity), in CH(3)CN solvent at -40 degrees C followed by solvent removal under vacuum at -40 degrees C yielded fac-OsO(3)F(2)(NCCH(3)).nCH(3)CN (n >/= 2). Continued pumping at -40 degrees C with removal of uncoordinated CH(3)CN yielded fac-OsO(3)F(2)(NCCH(3)). Both fac-OsO(3)F(2)(NCCH(3)).nCH(3)CN and fac-OsO(3)F(2)(NCCH(3)) are yellow-brown solids and were characterized by low-temperature (-150 degrees C) Raman spectroscopy. The crystal structure (-173 degrees C) of fac-OsO(3)F(2)(NCCH(3)).2CH(3)CN consists of two co-crystallized CH(3)CN molecules and a pseudo-octahedral OsO(3)F(2).NCCH(3) molecule in which three oxygen atoms are in a facial arrangement and CH(3)CN is coordinated trans to an oxygen atom in an end-on fashion. The Os---N bond length (2.205(3) A) is among the shortest M---N adduct bonds observed for a d(0) transition metal oxide fluoride. The (19)F NMR spectrum of (OsO(3)F(2))(infinity) in CH(3)CN solvent (-40 degrees C) is a singlet (-99.6 ppm) corresponding to fac-OsO(3)F(2)(NCCH(3)). The (1)H, (15)N, (13)C, and (19)F NMR spectra of (15)N-enriched OsO(3)F(2)(NCCH(3)) were recorded in SO(2)ClF solvent (-84 degrees C). Nitrogen-15 enrichment resulted in splitting of the (19)F resonance of fac-OsO(3)F(2)((15)NCCH(3)) into a doublet ((2)J((15)N-(19)F), 21 Hz). In addition, a doublet of doublets ((2)J((19)F(ax)-(19)F(eq)), 134 Hz; (2)J((15)N-(19)F(eq)), 18 Hz) and a doublet ((2)J((19)F(ax)-(19)F(eq)), 134 Hz) were observed in the (19)F NMR spectrum that have been assigned to mer-OsO(3)F(2)((15)NCCH(3)); however, coupling of (15)N to the axial fluorine-on-osmium environment could not be resolved. The nitrogen atom of CH(3)CN is coordinated trans to a fluorine ligand in the mer-isomer. Quantum-chemical calculations at the SVWN and B3LYP levels of theory were used to calculate the energy-minimized gas-phase geometries, vibrational frequencies of fac- and mer-OsO(3)F(2)(NCCH(3)) and of CH(3)CN. The

  4. The diagnostic accuracy of a single CEA blood test in detecting colorectal cancer recurrence: Results from the FACS trial.

    Directory of Open Access Journals (Sweden)

    Bethany Shinkins

    Full Text Available To evaluate the diagnostic accuracy of a single CEA (carcinoembryonic antigen blood test in detecting colorectal cancer recurrence.Patients who have undergone curative resection for primary colorectal cancer are typically followed up with scheduled CEA testing for 5 years. Decisions to investigate further (usually by CT imaging are based on single test results, reflecting international guidelines.A secondary analysis was undertaken of data from the FACS trial (two arms included CEA testing. The composite reference standard applied included CT-CAP imaging, clinical assessment and colonoscopy. Accuracy in detecting recurrence was evaluated in terms of sensitivity, specificity, likelihood ratios, predictive values, time-dependent area under the ROC curves, and operational performance when used prospectively in clinical practice are reported.Of 582 patients, 104 (17.9% developed recurrence during the 5 year follow-up period. Applying the recommended threshold of 5μg/L achieves at best 50.0% sensitivity (95% CI: 40.1-59.9%; in prospective use in clinical practice it would lead to 56 missed recurrences (53.8%; 95% CI: 44.2-64.4% and 89 false alarms (56.7% of 157 patients referred for investigation. Applying a lower threshold of 2.5μg/L would reduce the number of missed recurrences to 36.5% (95% CI: 26.5-46.5% but would increase the false alarms to 84.2% (924/1097 referred. Some patients are more prone to false alarms than others-at the 5μg/L threshold, the 89 episodes of unnecessary investigation were clustered in 29 individuals.Our results demonstrated very low sensitivity for CEA, bringing to question whether it could ever be used as an independent triage test. It is not feasible to improve the diagnostic performance of a single test result by reducing the recommended action threshold because of the workload and false alarms generated. Current national and international guidelines merit re-evaluation and options to improve performance, such as

  5. Solid-state thermolysis of a fac-rhenium(I) carbonyl complex with a redox non-innocent pincer ligand.

    Science.gov (United States)

    Jurca, Titel; Chen, Wen-Ching; Michel, Sheila; Korobkov, Ilia; Ong, Tiow-Gan; Richeson, Darrin S

    2013-03-25

    The development of rhenium(I) chemistry has been restricted by the limited structural and electronic variability of the common pseudo-octahedral products fac-[ReX(CO)3L2] (L2 = α-diimine). We address this constraint by first preparing the bidentate bis(imino)pyridine complexes [(2,6-{2,6-Me2C6H3N=CPh}2C5H3N)Re(CO)3X] (X = Cl 2, Br 3), which were characterized by spectroscopic and X-ray crystallographic means, and then converting these species into tridentate pincer ligand compounds, [(2,6-{2,6-Me2C6H3N=CPh}2C5H3N)Re(CO)2X] (X = Cl 4, Br 5). This transformation was performed in the solid-state by controlled heating of 2 or 3 above 200 °C in a tube furnace under a flow of nitrogen gas, giving excellent yields (≥95 %). Compounds 4 and 5 define a new coordination environment for rhenium(I) carbonyl chemistry where the metal center is supported by a planar, tridentate pincer-coordinated bis(imino)pyridine ligand. The basic photophysical features of these compounds show significant elaboration in both number and intensity of the d-π* transitions observed in the UV/Vis spec tra relative to the bidentate starting materials, and these spectra were analyzed using time-dependent DFT computations. The redox nature of the bis(imino)pyridine ligand in compounds 2 and 4 was examined by electrochemical analysis, which showed two ligand reduction events and demonstrated that the ligand reduction shifts to a more positive potential when going from bidentate 2 to tridentate 4 (+160 mV for the first reduction step and +90 mV for the second). These observations indicate an increase in electrostatic stabilization of the reduced ligand in the tridentate conformation. Elaboration on this synthetic methodology documented its generality through the preparation of the pseudo-octahedral rhenium(I) triflate complex [(2,6-{2,6-Me2C6H3N=CPh}2C5H3N)Re(CO)2OTf] (7, 93 % yield). Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. Formation of a Six-Coordinate fac-[Re(Co)3]+ Complex by the N-C bond cleavage of a potentially tetradentate ligand

    International Nuclear Information System (INIS)

    Booysen, I.; Gerber, T. I. A.; Hosten, E.; Mayer, P.

    2008-01-01

    The rhenium(I) compound fac-[Re(CO) 3 (daa)]. Hpab.H 2 O (Hpab N,N'-(l,2-phenylene)bis(2'-aminobenzamide); Hdaa 2-amino-N-(2-aminophenyl)benzamide) was synthesized from the reaction of [Re(CO) 5 ,Br] with two equivalent of Hpab in toluene. The monoanionic tridentate ligand daa was formed by the rhenium-mediated cleavage of an amido N-C bond of the potentially tetradentate ligand Hpab. The compound was characterized by IR spectroscopy and X-ray crystallography, and daa is coordinated as a diamino amide via three nitrogen-donor atoms

  7. Serendipitous preparation of fac-(acetonitrile-κNtrichlorido[(1,2,5,6-η-cycloocta-1,5-diene]iridium(III

    Directory of Open Access Journals (Sweden)

    David M. Morris

    2015-04-01

    Full Text Available A reaction between [(CODIrCl]2 (COD is cycloocta-1,5-diene, HCl and indene failed to provide the hoped for chloridoindenyliridium dimer, but instead produced the title compound, [IrCl3(CH3CN(C8H12], which is an octahedral complex of iridium(III with a chelating cycloocta-1,5-diene ligand, three chloride ligands in a fac arrangement, and one acetonitrile ligand. Attempts to devise a rational synthesis for the title compound were unsuccessful.

  8. Evaluasi Tingkat Kesiapan Organisasi dalam Rangka Preservasi Digital (Studi Kasus Pada Unit Repositori Flinders Academic Commons Of Flinders University Library (FACFUL, Adelaide, Australia Selatan

    Directory of Open Access Journals (Sweden)

    Rattahpinnusa Haresariu Handisa

    2017-12-01

    Full Text Available Penelitian ini bertujuan mengidentifikasi tingkat kesiapan lembaga repositori dalam rangka preservasi digital pada Flinders Academic Commons Flinders University Library (FACFUL dan mengidentifikasi faktor-faktor yang berpengaruh terhadap tingkat kesiapan organisasi. Terdapat tiga aspek yang diteliti meliputi: kesiapan infrastruktur, kesiapan teknologi serta sumber daya yang dibutuhkan bagi preservasi digital. Penelitian ini menggunakan metode studi kasus dengan  intesity sampel. Adapun instrumen pengumpulan data menggunakan Cornell University Survey of Institutional Readiness Checklist. Selanjutnya, tehnik pengambilan data menggunakan tehnik wawancara dengan Ms. Liz-Walkley Hall selaku pustakawati yang bertanggung jawab terhadap unit repositori digital FACFUL. Adapun informasi penunjang diperoleh melalui studi kepustakaan merujuk pada website Perpustakaan Universitas  Flinders. Data yang terkumpul dianalisis secara deskriptif menggunakan indikator kesiapan organisasi Cornel University Model. Hasil penelitian menunjukkan bahwa unit repositori pada FACFUL kurang siap dalam menjalankan preservasi digital. Tingkat kesiapan organisasi Perpustakaan Universitas  Flinders dalam pelestarian digital berapa pada level terbawah yakni Acknowledgement . Pada tingkat tersebut, Perpustakaan Flinders masih dalam tahap pengembangan kesadaran tentang pentingnya preservasi digital. Selanjutnya, faktor-faktor yang mempengaruhi rendahnya tingkat kesiapan organisasi tersebut adalah tidak adanya pernyataan pentingya preservasi digital pada kebijakan pengembangan koleksi; keterbatasan pendanaan dan keterbatasan sumber daya manusia yang kompeten dalam preservasi digital. Penelitian ini merekomendasikan Perpustakaan Universitas Flinders untuk  melakukan uji kelayakan bagi preservasi digital. Salah satu model bisnis yang sesuai dengan kondisi Perpustakaan Universitas  Flinders adalah Meta Archive Model (MAM. Model tersebut berbasis komunitas bagi preservasi digital

  9. Prototipo de simulador de tornado para el combate Aéreo No. 3 (CACOM 3 de la Fuerza Aérea Colombiana (FAC

    Directory of Open Access Journals (Sweden)

    Jorge Mario Cárdenas Cabrera

    2012-09-01

    El comando CACOM 3 de la Fuerza Aérea Colombiana (FAC ha tomado la iniciativa en este aspecto y se ha dado a la tarea de estudiar este fenómeno, trabajando en el diseño de un simulador de tornados a escala, con base en el ya existente, desarrollado por el phD. Harald Eddens, introdujo modificaciones que permitan, además de generar el fenómeno, medir y controlar a través de dispositivos electrónicos algunas variables ambientales. Estos dispositivos permitirán iniciar estudios desde el comando y servir de apoyo para labores de educación de la población vulnerable en cuanto a entender cómo se forma un tornado.

  10. Intersystem-crossing and phosphorescence rates in fac-Ir{sup III}(ppy){sub 3}: A theoretical study involving multi-reference configuration interaction wavefunctions

    Energy Technology Data Exchange (ETDEWEB)

    Kleinschmidt, Martin; Marian, Christel M., E-mail: Christel.Marian@hhu.de [Institute of Theoretical and Computational Chemistry, Heinrich-Heine-University Düsseldorf, Universitätsstraße 1, 40225 Düsseldorf (Germany); Wüllen, Christoph van [Fachbereich Chemie and Forschungszentrum OPTIMAS, Technical University of Kaiserslautern, Erwin-Schrödinger-Straße 52, 67663 Kaiserslautern (Germany)

    2015-03-07

    We have employed combined density functional theory and multi-reference configuration interaction methods including spin–orbit coupling (SOC) effects to investigate the photophysics of the green phosphorescent emitter fac-tris-(2-phenylpyridine)iridium (fac-Ir(ppy){sub 3}). A critical evaluation of our quantum chemical approaches shows that a perturbational treatment of SOC is the method of choice for computing the UV/Vis spectrum of this heavy transition metal complex while multi-reference spin–orbit configuration interaction is preferable for calculating the phosphorescence rates. The particular choice of the spin–orbit interaction operator is found to be of minor importance. Intersystem crossing (ISC) rates have been determined by Fourier transformation of the time correlation function of the transition including Dushinsky rotations. In the electronic ground state, fac-Ir(ppy){sub 3} is C{sub 3} symmetric. The calculated UV/Vis spectrum is in excellent agreement with experiment. The effect of SOC is particularly pronounced for the metal-to-ligand charge transfer (MLCT) band in the visible region of the absorption spectrum which does not only extend its spectral onset towards longer wavelengths but also experiences a blue shift of its maximum. Pseudo-Jahn-Teller interaction leads to asymmetric coordinate displacements in the lowest MLCT states. Substantial electronic SOC and a small energy gap make ISC an ultrafast process in fac-Ir(ppy){sub 3}. For the S{sub 1}↝T{sub 1} non-radiative transition, we compute a rate constant of k{sub ISC} = 6.9 × 10{sup 12} s{sup −1} which exceeds the rate constant of radiative decay to the electronic ground state by more than six orders of magnitude, in agreement with the experimental observation of a subpicosecond ISC process and a triplet quantum yield close to unity. As a consequence of the geometric distortion in the T{sub 1} state, the T{sub 1} → S{sub 0} transition densities are localized on one of the

  11. YoichiroNambu: Seer* ofModernPhysics

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 14; Issue 6. Yoichiro Nambu: Seer of Modern Physics. N D Hari Dass. General Article Volume 14 Issue 6 June 2009 pp ... DAE Raja Ramanna Fellow, Indian Institute of Science, Bangalore 560 012, India. Hon. Director, Poornaprajna Institute of Scientific ...

  12. H:\\PMKER 25(1)\\PDF 25(1)\\KIKOUN.xps

    African Journals Online (AJOL)

    AISA

    évolution de la richesse, de la pureté ..... Richesse au labo agro = 100 x Somme Tonnes ..... Sugar industry technologists ; NEW YORK, éd. S.I.T. 298 p. Hildebrand C., 2002. An independent assessment of the sugar industry. Report to the Hon Truss ...

  13. Building Relationships through a Digital Branch Library: Finding the Community in Community College Library Websites

    Science.gov (United States)

    Pampaloni, Andrea M.; Bird, Nora J.

    2014-01-01

    This study evaluates whether or not community college libraries have in place the characteristics necessary to develop digital branch libraries to meet the expanding and changing needs of their publics. Using Hon and Grunig's (1999) relationship building criteria as a framework, 98 community college library websites were analyzed to determine…

  14. Download this PDF file

    African Journals Online (AJOL)

    NESG PUBLICATIONS

    United Kingdom, France, Germany and the nations of the European Union, ..... and Chinweizu that a past history of ..... As illustrated in our review of the .... Professor Anya O. Anya, Ph.D (Cambridge), D.Sc (Hon), FAS, OFR, NNOM, is a Policy ...

  15. Students as Producers: An "X" Disciplinary Client-Based Approach to Collaborative Art, Design and Media Pedagogy

    Science.gov (United States)

    Cocchiarella, Fabrizio; Booth, Paul

    2015-01-01

    This article presents the findings of a cross-disciplinary project between BA (Hons) Interior Design, Creative Multimedia and Film and Media Studies at a large Metropolitan University in the North of England. The collaboration was part of Unit X, a faculty-wide credit-bearing initiative to enable better collaboration across art and design courses.…

  16. Southern Africa Journal of Education, Science and Technology ...

    African Journals Online (AJOL)

    BCom Management (Finance (MSU), MCom Strategic Management and Corporate Governance (MSU), Diploma in Education (GTC). Prof. G. Nyamadzawo. BSc (Hons) Agriculture (Soil Science) (UZ), MPhil Agriculture (Soil Science) (UZ), MSc Agriculture (WSU, USA), Diploma in Education, PhD (UZ). ISSN: 1819-3692.

  17. Selecting Candidates for Key Leadership Positions in Program Executive Offices Ground Combat Systems and Combat Service and Combat Service Support

    Science.gov (United States)

    2016-10-14

    start or continue a profitable growth pattern and boost morale and motivation, a poor decision may bring the company to the brink of financial...HON Frank Kendall issued a memorandum titled “Key Leadership Positions and Qualification Criteria” (Kendall, 2013). This memorandum provides a...Chief Developmental Tester • Program Lead, Business Financial Manager SELECTING CANDIDATES FOR KEY LEADERSHIP POSITIONS 4

  18. Entrance Qualifications Affect the Performance of Nutrition Students at University: A Pilot Study

    Science.gov (United States)

    Owusu-Apenten, Richard; Xu, Wen Li

    2012-01-01

    This study assessed the effect of admissions qualifications on the subsequent academic performances of BSc nutrition students at a UK university. Entrance qualifications for three groups (Grp01, Grp02, Grp03) reading for a BSc(Hons) degree in, Dietetics, Food & Nutrition or Human Nutrition (n = 105) were determined from their UCAS…

  19. Ownership and human tissue – the legal conundrum: A response to ...

    African Journals Online (AJOL)

    , has created confusion and misperception which ... S Mahomed,1 BCom, LLB, LLM, PhD Candidate; M Nöthling-Slabbert,2 BA Hons, MA, DLitt, LLB, LLD; M S Pepper,3 MB ChB, PhD, MD ... There are abundant examples in law showing.

  20. Coal industry - minutes of evidence - Wednesday 19 February 1986

    Energy Technology Data Exchange (ETDEWEB)

    1986-01-01

    Evidence to the House of Common's Energy Committee on the future of the coal industry was presented by the Secretary of State for Energy, Rt. Hon. Peter Walker, MBE, MP. Topics presented included: investment; NCB (Enterprise); the coal firing scheme, pit closures; labor relations and the future in general.

  1. New Fellows and Honorary Fellow

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1935 Section: Mathematical Sciences. Mahalanobis, Prasanta Chandra M.A. (Cantab), Hon. D.Sc. (Calcutta), FNA, FNASc. Date of birth: 29 June 1893. Date of death: 28 June 1972. Specialization: Statistics. YouTube; Twitter; Facebook; Blog ...

  2. Developing Professional Learning for Staff Working with Children with Speech, Language and Communication Needs Combined with Moderate-Severe Learning Difficulties

    Science.gov (United States)

    Anderson, Carolyn

    2011-01-01

    This article presents research undertaken as part of a PhD by Carolyn Anderson who is a senior lecturer on the BSc (Hons) in Speech and Language Pathology at the University of Strathclyde. The study explores the professional learning experiences of 49 teachers working in eight schools and units for children with additional support needs in…

  3. New Fellows and Honorary Fellow

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 1972 Section: Engineering & Technology. Kumaraswamy, Ponnambalam B.E. (Hons). Date of birth: 4 October 1930. Date of death: 9 March 1988. Specialization: Hydraulics, Hydrology and Computer Simulation. YouTube; Twitter; Facebook; Blog ...

  4. Is ozonation environmentally benign for reverse osmosis concentrate treatment? Four-level analysis on toxicity reduction based on organic matter fractionation.

    Science.gov (United States)

    Weng, Jingxia; Jia, Huichao; Wu, Bing; Pan, Bingcai

    2018-01-01

    Ozonation is a promising option to treat reverse osmosis concentrate (ROC). However, a systematic understanding and assessment of ozonation on toxicity reduction is insufficient. In this study, ROC sampled from a typical industrial park wastewater treatment plant of China was fractionated into hydrophobic acid (HOA), hydrophobic base (HOB), hydrophobic neutral (HON), and hydrophilic fraction (HI). Systematic bioassays covering bacteria, algae, fish, and human cell lines were conducted to reveal the role of ozonation in toxicity variation of the four ROC fractions. HOA in the raw ROC exhibited the highest toxicity, followed by HON and HI. Ozonation significantly reduced total organic carbon (TOC) and UV 254 values in HOA, HON, and HI and their toxicity except in HOB. Correlation analysis indicated that chemical data (TOC and UV 254 ) of HOA and HON correlated well with their toxicities; however, poor correlations were observed for HOB and HI, suggesting that a battery of toxicity assays is necessary. This study indicates that TOC reduction during ozonation could not fully reflect the toxicity issue, and toxicity assessment is required in conjunction with the chemical data to evaluate the effectiveness of ozonation. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. Electronic [Re]Constitution of Groups: Group Dynamics from Face-to-Face to an Online Setting

    Science.gov (United States)

    Clouder, Lynn; Dalley, Jayne; Hargreaves, Julian; Parkes, Sally; Sellars, Julie; Toms, Jane

    2006-01-01

    The authors work as online tutors for a BSc (Hons) physiotherapy programme at Coventry University in the United Kingdom. This paper represents a stage in our developing understanding, over a 3 year period, of the impact of group dynamics on online interaction among physiotherapy students engaged in sharing with their peers their first experiences…

  6. 9 June 2016 - British Foreign and Commonwealth Office, Minister of State H. Swire MP signing the guest book with CERN Director-General F. Gianotti.

    CERN Multimedia

    Bennett, Sophia Elizabeth

    2016-01-01

    The Rt Hon Hugo Swire MP Minister of State Foreign and Commonwealth Office United Kingdom of Great Britain and Northern Ireland; in the LHC superconducting magnet test hall with Beams Department Head P. Collier and in ATLAS Visitor Centre with ATLAS Collaboration Spokesperson D. Charlton.

  7. Resonance – Journal of Science Education | News

    Indian Academy of Sciences (India)

    Programming Languages - A Brief Review. V Rajaraman ... V Rajaraman1 2. IBM Professor of Information Technology, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore 560012, India; Hon.Professor, Supercomputer Education & Research Centre Indian Institute of Science, Bangalore 560012, India ...

  8. Meeting

    Indian Academy of Sciences (India)

    1986-11-07

    Nov 7, 1986 ... The Hon'ble Mr. Kamalakanta Verma, Chief. Justice, High Court of .... financial support from the Maharashtra State. Khadi and .... as a Cane Breeding Officer at the Central ... where he played a notable role in the breeding of ...

  9. Wound Dressing Procedure and Prevention of Contamination and ...

    African Journals Online (AJOL)

    Malawi Medical Journal. Wound Dressing Procedure and Prevention of Contamination and. Cross Infection. By: Chimwaza AF, MRN, MRN, Bsc (Hons) MSN Lecturer. Kachingwe-Sisya M., MRN, MRM. Bsc Nsg Edu. & Adm. MSN. Lecturer. Medical Surgical Nursing Department. Kamuzu College of Nursing. Blantyre. Malawi.

  10. TEQSA Annual Report 2015-2016

    Science.gov (United States)

    Australian Government Tertiary Education Quality and Standards Agency, 2016

    2016-01-01

    This report informs Senator the Hon. Simon Birmingham, Minister for Education and Training, the Parliament of Australia, the Australian higher education community and the general public about the performance of the Tertiary Education Quality and Standards Agency (TEQSA or the Agency) during the financial year ending 30 June 2016. Prepared…

  11. COLOUR LEARNING IN RETARDED CHILDREN*

    African Journals Online (AJOL)

    COLOUR LEARNING IN RETARDED CHILDREN* !\\'fRS E. K~SEBOOM, Principal, ADS. LEVIN, M.B., M.R.C.P., D.C.H., Hon. Medical Officer, Hamlet B School for. Retarded Children, Johannesburg. '... silly children, with no understanding .. -'. Jeremiah 4:22. Tt has been observed' that mentally retarded children have.

  12. New Fellows and Honorary Fellow

    Indian Academy of Sciences (India)

    ... Discussion Meetings · Public Lectures · Lecture Workshops · Refresher Courses · Symposia. Home; Fellowship. Fellow Profile. Elected: 1934 Section: Plant Sciences. Parija, Prankrishna M.A. (Cantab), D.Sc. (Hon.), FNA, FNASc. Date of birth: 1 April 1891. Date of death: 2 June 1978. Specialization: Plant Physiology and ...

  13. 76 FR 61742 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance and...

    Science.gov (United States)

    2011-10-05

    ...: August 1, 2010 TA-W-80,353; The HON Company, Owensboro, KY: August 4, 2011 TA-W-80,393; SOLON Corp... workers cannot be covered by more than one certification at a time. TA-W-80,328; Siemens Medical Solutions...

  14. Development of Toxicity Benchmarks for Nitrogen-based Energetic Materials for the Enchytraeid Worm, Enchytraeus crypticus

    Science.gov (United States)

    2013-11-01

    oats spread onto the soil surface. If food from the previous feeding date remained on the soil surface, the amount of food added was adjusted. Every...138. Emery, E.F.; Junk , T.; Ferrell, R.E., Jr.; De Hon, R.; Butler, L.G. Solid-State 2 H MAS NMR Studies of TNT Absorption in Soil and Clays

  15. Biology as an Integrating Natural Science Domain

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 13; Issue 3. Biology as an Integrating Natural Science Domain: A Proposal for BSc (Hons) in Integrated Biology. Kambadur Muralidhar. Classroom Volume 13 Issue 3 March 2008 pp 272-276 ...

  16. Strategies and Procedures for Expediting Election Petitions

    African Journals Online (AJOL)

    Mofasony

    person the right to have his civil rights and obligations determined by a court after a fair hearing and within .... T. Osipitan, “Problems of Proof under the Electoral Act 2002,” Judicial Excellence, Essays in. Honour of Hon. ..... voting at all.73. 241.

  17. Development of Health Education Learning Module in Bac.TSE-LDPE Programme in TTI: Needs Analysis Study

    Science.gov (United States)

    Ujang, Alijah; Alias, Norlidah; Siraj, Saedah

    2015-01-01

    This study is to explore the need to develop learning modules of health education for trainee teachers in the Bachelor Of Teaching (Hons)(Special Education-Learning Disabilities For Primary Education) Programme (Bac.TSE-LDPE) in the Teacher Training Institute (TTI). The questionnaire uses the Likert scale with the close ended questions analysed by…

  18. Integrating Research-Informed Teaching within an Undergraduate Level 4 (Year 1) Diagnostic Radiography Curriculum: A Pilot Study

    Science.gov (United States)

    Higgins, Robert; Hogg, Peter; Robinson, Leslie

    2013-01-01

    This article discusses the piloting and evaluation of the Research-informed Teaching experience (RiTe) project. The aim of RiTe was to link teaching and learning with research within an undergraduate diagnostic radiography curriculum. A preliminary pilot study of RiTe was undertaken with a group of level 4 (year 1) volunteer BSc (Hons) diagnostic…

  19. Native American Languages Act. Hearing before the Committee on Indian Affairs, United States Senate. One Hundred Eighth Congress, First Session on S. 575 To Amend the Native American Languages Act To Provide for the Support of Native American Language Survival Schools (May 15, 2003).

    Science.gov (United States)

    Congress of the U.S., Washington, DC. Senate Committee on Indian Affairs.

    This document includes statements given at this hearing by the following: William Y. Brown; John Cheek, Jennifer Chock; Rita Coosewon; David Dinwoodie; William Demmert, Jr.; Joycelyn DesRosier; Mary Hermes; Carla Herrera; Leanne Hinton; Holo Ho'opai; Hon. Daniel K. Inouye; Lawrence D. Kaplan; Keiki Kawaiaea; Rosalyn, LaPier; Lisa LaRonge; Vina…

  20. Foraging behavior of the Blue Morpho and other tropical butterflies: The chemical and electrophysiological basis of olfactory preferences and the role of color

    Science.gov (United States)

    Inside a live butterfly exhibit housing a variety of tropical butterfly species under north-central Florida ambient conditions, we conducted bioassays to determine whether the presence of color would facilitate the location of attractants by the butterflies. In two separate bioassays, the baits (hon...

  1. 40 CFR 63.1434 - Equipment leak provisions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 11 2010-07-01 2010-07-01 true Equipment leak provisions. 63.1434... Standards for Hazardous Air Pollutant Emissions for Polyether Polyols Production § 63.1434 Equipment leak provisions. (a) The owner or operator of each affected source shall comply with the HON equipment leak...

  2. East Asia: Southeast Asia

    Science.gov (United States)

    1990-09-05

    supporting role in the founding of Malaysia. Some people describe their role as having a position but having no authority. During the cogon grass campaign...Pian Hon Yun Shih-chin’s luck was much greater than Kuo Wei- chieh’s. Although both are deputy ministers, their grass - roots power is weak. Kuo

  3. 100eme anniversaire de la théorie de la relativité Une BD romande : Mélanges Einstein (Albert) et l'histoire de la physique

    CERN Multimedia

    Tesnier, Grégory

    2005-01-01

    2005 has been delcared "Year of Physics" by UNESCO and ONU to celebrate the 100th anniversary of the theory of relativity, elaborated by Einstein (who lived in Bern). To hon. Einstein, an historical comic strip has been published (1 page)

  4. Perception for Outdoor Navigation

    Science.gov (United States)

    1990-11-01

    the problemn simple by fitting mathematical mdels to the terrai ends up with a mremtmfn that is Just as intratable a anlevaionmap. luand, of looking...particula mW locaton or object Annowatons can tuag hon high- lvel (’church") io geameftic ("steeple helgi 25A, .0) to mmwo-pcific ("look for long nearly

  5. The effect of prophylactic knee bracing on proprioception ...

    African Journals Online (AJOL)

    Enrique

    S Davies (BA Hons, MA Ergonomics, PhD). Department of Human ... of joint position in space as sensed by the central nervous system.23. It incorporates joint .... The finding of this work supports the research hypothesis that prophylactic knee ...

  6. 77 FR 74182 - Records Governing Off-the-Record Communications; Public Notice

    Science.gov (United States)

    2012-12-13

    .... CP11-515-000 12-6-12 Thomas Salamone 3. CP11-515-000 12-6-12 Michael Mojica \\1\\ Exempt 1. CP13-8-000 11...-000 12-4-12 Kate Valdez \\1\\ Email record. \\2\\ Phone record. \\3\\ Email record. \\4\\ Hons. Rob Kane and...

  7. Divine Interventions: Needs Analysis for Post-Graduate Academic Literacy and Curriculum Development, in a South African School of Theology

    Science.gov (United States)

    Jackson, Fiona

    2005-01-01

    This paper provides a critical exploration of work in progress to develop a genre based academic support that promotes post-graduate academic literacies among new EIL and EAL Hons and Masters students in the School of Theology, University of Natal, Pietermaritzburg. It traces the path of an action research project, using an eclectic needs analysis…

  8. 77 FR 2291 - Records Governing Off-the-Record Communications; Public Notice

    Science.gov (United States)

    2012-01-17

    ... Support at [email protected] or toll free at (866) 208-3676, or for TTY, contact (202) 502-8659.... CP12-30-000 12-15-11 Hon. Leonard Lance. 11. P-14263-000 12-16-11 Gov. Matthew H. Mead. 12. CP11-14-000...

  9. Classroom

    Indian Academy of Sciences (India)

    sharing personal experiences and viewpoints on matters related to teaching and learning science. Abhishek Saha. B. Math. Hons. 1st year ... Proof. Let Pb P2,. ,Ps be the various distinct prime divisors of p - 1. Thus. E=.!. k p-1 s. Pj.

  10. Fulltext PDF

    Indian Academy of Sciences (India)

    sharing personal experiences and viewpoints on matters related to teaching and learning science. Somnath Basu. B. Math. Hons. lind year .... Here are sorn.e more identities which can easily be proved using induction. We leave the proofs as ...

  11. The Enigmatic Nature of the Israeli Legal System

    African Journals Online (AJOL)

    MJM Venter

    important conceptual instruments in support of the arguments developed in this article are clarified. Thereafter, in part 4 I concisely posit, without arguing in detail, the basic thesis on the factual dimension of law. The thesis casts doubt on the claims of the. *. Koos Malan. BA Hons (UP), BIur LLB LLD (UNISA) Professor of ...

  12. Pyrazolyl conjugates of bombesin: a new tridentate ligand framework for the stabilization of fac-[M(CO){sub 3}]{sup +} moiety

    Energy Technology Data Exchange (ETDEWEB)

    Alves, Susana; Correia, Joao D.G.; Santos, Isabel [Departamento de Quimica, Instituto Tecnologico e Nuclear, 2686-953 Sacavem (Portugal); Veerendra, Bhadrasetty [Department of Radiology, University of Missouri-Columbia School of Medicine, Columbia, MO 65211 (United States); Sieckman, Gary L. [Research Division, Harry S. Truman Memorial Veterans' Hospital, Columbia, MO 65201 (United States); Hoffman, Timothy J. [Research Division, Harry S. Truman Memorial Veterans' Hospital, Columbia, MO 65201 (United States)]|[Department of Internal Medicine, University of Missouri-Columbia School of Medicine, Columbia, MO 65211 (United States)]|[Radiopharmaceutical Sciences Institute, University of Missouri-Columbia School of Medicine, Columbia, MO 65211 (United States); Rold, Tammy L. [Department of Internal Medicine, University of Missouri-Columbia School of Medicine, Columbia, MO 65211 (United States); Figueroa, Said Daibes [Radiopharmaceutical Sciences Institute, University of Missouri-Columbia School of Medicine, Columbia, MO 65211 (United States); Retzloff, Lauren [Department of Radiology, University of Missouri-Columbia School of Medicine, Columbia, MO 65211 (United States); McCrate, Joseph [Department of Radiology, University of Missouri-Columbia School of Medicine, Columbia, MO 65211 (United States); Prasanphanich, Adam [Department of Radiology, University of Missouri-Columbia School of Medicine, Columbia, MO 65211 (United States); Smith, Charles J. [Department of Radiology, University of Missouri-Columbia School of Medicine, Columbia, MO 65211 (United States)]|[University of Missouri Research Reactor Center, University of Missouri-Columbia, Columbia, MO 65211 (United States)]|[Research Division, Harry S. Truman Memorial Veterans' Hospital, Columbia, MO 65201 (United States)]|[Department of Internal Medicine, University of Missouri-Columbia School of Medicine, Columbia, MO 65211 (United States)]. E-mail: smithcj@health.missouri.edu

    2006-07-15

    We have described the synthesis of tridentate pyrazolyl ligand frameworks for coordination to the fac-[*M(CO){sub 3}]{sup +} metal fragment (*M={sup 186/188}Re or {sup 99m}Tc). These ligands impart a degree of kinetic inertness on the metal center, warranting their study in biological systems. We herein report in vitro/in vivo radiolabeling investigations of a new series of pyrazolyl bombesin (BBN) conjugates radiolabeled via the Isolink kit. These new conjugates are based on the general structure [{sup 99m}Tc-pyrazolyl-X-BBN[7-14]NH{sub 2}], where X={beta}-alanine, serylserylserine or glycylglycylglycine. The pyrazolyl ligand is a tridentate ligand framework that coordinates the metal center through nitrogen donor atoms. The results of these investigations demonstrate the ability of these new conjugates to specifically target the gastrin-releasing peptide receptor subtype 2, which is overexpressed on human prostate PC-3 cancerous tissues. Therefore, these studies suggest the tridentate pyrazolyl ligand framework to be an ideal candidate for the design and development of low-valent {sup 99m}Tc-based diagnostic radiopharmaceuticals based on BBN or other targeting vectors.

  13. C-C coupling of N-heterocycles at the fac-Re(CO)(3) fragment: synthesis of pyridylimidazole and bipyridine ligands.

    Science.gov (United States)

    Viguri, Maialen Espinal; Pérez, Julio; Riera, Lucía

    2014-05-05

    A new family of cationic rhenium tricarbonyl complexes with either two N-alkylimidazole (N-RIm) and one pyridine (Py) ligand, or two pyridine and one N-RIm ligand, [Re(CO)3 (N-RIm)(3-x) (Py)x ](+) , has been prepared. The reaction of these complexes with a strong base, followed by an oxidant, selectively afforded 2,2'-pyridylimidazole complexes as the result of intramolecular dehydrogenative CC coupling reactions. For tris(pyridine) complexes [Re(CO)3 (Py)3 ](+) the reaction pattern upon a deprotonation/oxidation sequence is maintained, which allows the generation of complexes with 2,2'-bipyridine ligands. In the particular combination of two different types of pyridine ligand in the cationic fac-Re(CO)3 complexes only the cross-coupling products with asymmetric 2,2'-bipyridine ligands were obtained; the homocoupling products were not observed. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. Representações sociais e território nas letras de funk proibido de facção

    Directory of Open Access Journals (Sweden)

    Andréa Rodriguez

    2011-12-01

    Full Text Available Este artigo apresenta, por meio de uma análise de letras de funk “proibido de facção”, uma leitura da territorialidade do tráfico de drogas nas favelas. Esse estilo musical, que expressa uma cultura específica da juventude urbana pobre, revela cenas de um cotidiano pouco conhecido pela maior parte da população. Para tal, foi realizada a análise do conteúdo de 50 letras de funk, de forma a se compreenderem questões que esse tipo de narrativa faz circular. Destaca-se o território e a territorialidade como categorias de análise que revelam a dinâmica que o tráfico de drogas impõe nos espaços populares da cidade e que incidem diretamente nas representações sociais e práticas dos moradores das favelas.

  15. Evaluation of LINE-1 mobility in neuroblastoma cells by in vitro retrotransposition reporter assay: FACS analysis can detect only the tip of the iceberg of the inserted L1 elements

    International Nuclear Information System (INIS)

    Del Re, Brunella; Marcantonio, Pamela; Capri, Miriam; Giorgi, Gianfranco

    2010-01-01

    Long Interspersed Nuclear Elements (L1) are retroelements generally repressed in most differentiated somatic cells. Their activity has been observed in some undifferentiated and tumour cells and could be involved in tumour onset and progression. Growing evidences show that the L1 activation can occur in neuronal precursor cells during differentiation process. Neuroblastoma is a tumour originating from neuronal precursor cells, and, although the molecular basis of its progression is still poorly understood, the implication of L1 activation has not yet been investigated. In this study L1 mobility in neuroblastoma BE(2)C cells was assessed using the in vitro retrotransposition assay consisting in an episomal EGFP-tagged L1 RP element, whose mobility can be evaluated by cytofluorimetric analysis (FACS) of EGFP expression. FACS results have shown a low retrotransposition activity. To detect L1 RP integrated in transcriptionally repressed genomic sites, both a cell treatment with a stimulator of reporter gene promoter, and a quantitative Real-Time PCR analysis were performed. A retrotransposition activity ten and one thousand times that of FACS was found, respectively. These results point out that the real rate of L1 retrotransposition events in tumour cells might be considerably higher than that reported so far by evaluating only the reporter gene expression.

  16. Comparative kinetics of damage to the plasma and mitochondrial membranes by intra-cellularly synthesized and externally-provided photosensitizers using multi-color FACS.

    Science.gov (United States)

    Haupt, Sara; Malik, Zvi; Ehrenberg, Benjamin

    2014-01-01

    Photodynamic therapy (PDT) of cancer involves inflicting lethal damage to the cells of malignant tumors, primarily by singlet oxygen that is generated following light-absorption in a photosensitizer molecule. Dysfunction of cells is manifested in many ways, including peroxidation of cellular components, membrane rupture, depolarization of electric potentials, termination of mitochondrial activity, onset of apoptosis and necrosis and eventually cell lysis. These events do not necessarily occur in linear fashion and different types of damage to cell components occur, most probably, in parallel. In this report we measured the relative rates of damage to two cellular membranes: the plasma membrane and the mitochondrial membrane. We employed photosensitizers of diverse hydrophobicities and used different incubation procedures, which lead to their different intra-cellular localizations. We monitored the damage that was inflicted on these membranes, by employing optical probes of membrane integrity, in a multi-color FACS experiment. The potentiometric indicator JC-1 monitored the electric cross-membrane potential of the mitochondria and the fluorometric indicator Draq7 monitored the rupture of the plasma membrane. We show that the electric depolarization of the mitochondrial membrane and the damage to the enveloping plasma membrane proceed with different kinetics that reflect the molecular character and intracellular location of the sensitizer: PpIX that is synthesized in the cells from ALA causes rapid mitochondrial damage and very slow damage to the plasma membrane, while externally added PpIX has an opposite effect. The hydrophilic sensitizer HypS4 can be taken up by the cells by different incubation conditions, and these affect its intracellular location, and as a consequence either the plasma membrane or the mitochondria is damaged first. A similar correlation was found for additional extracellularly-provided photosensitizers HP and PpIX.

  17. Sixteen years follow-up results of a randomized phase II trial of neoadjuvant fluorouracil, doxorubicin, and cyclophosphamide (FAC) compared with cyclophosphamide, methotrexate, and 5-fluorouracil (CMF) in stage III breast cancer: GOCS experience.

    Science.gov (United States)

    Leone, José Pablo; Leone, Julieta; Vallejo, Carlos Teodoro; Pérez, Juan Eduardo; Romero, Alberto Omar; Machiavelli, Mario Raul; Romero Acuña, Luis; Domínguez, María Ester; Langui, Mario; Fasce, Hebe Margot; Leone, Bernardo Amadeo; Ortiz, Eduardo; Iturbe, Julián; Zwenger, Ariel Osvaldo

    2014-01-01

    Neoadjuvant chemotherapy (NAC) allows direct evaluation of the tumor's sensitivity to therapy, eradication of micrometastatic disease and the possibility of performing breast conserving surgery. The aim of this study was to describe long-term results of NAC in stage III breast cancer patients. We evaluated 126 patients that participated in a phase II randomized trial of neoadjuvant FAC compared with CMF. Chemotherapy was administered for three cycles prior to definitive surgery and radiotherapy, and then for six cycles as adjuvant. Median follow-up was 4.5 years (range 0.2-16.4). Objective response rate (OR) was similar in both groups (61 % for FAC, 66 % for CMF, P = NS). There were no differences in median disease free survival (DFS) or overall survival (OS) (5.1 vs 3.3 years and 6.7 vs 6.3 years for FAC and CMF, respectively). After 16 years of follow-up, 53 patients are still alive. Multivariate analysis showed that the number of pathologically involved lymph nodes (pLN) was the only factor associated with both, DFS and OS (P = 0.0003 and P = 0.0005, respectively). Both regimens were well tolerated, CMF had higher incidence of grade 3-4 leukopenia, thrombocytopenia, and stomatitis, whereas alopecia was more common in FAC. To the best of our knowledge, this is the first study to report long-term outcomes of FAC and CMF in the neoadjuvant setting. Within the sensitivity of our study, both regimens showed similar OR, long-term toxicity, DFS, and OS rate at 16 years. After 5 years, the hazard of death seems to decline. The prolonged follow-up of this study provides a unique opportunity to evaluate factors that predict long-term outcomes. After 16 years of follow-up, the number of pLN remains the most powerful predictor of survival.

  18. Melanoma targeting with alpha-melanocyte stimulating hormone analogs labeled with fac-[99mTc(CO)3]+: effect of cyclization on tumor-seeking properties.

    Science.gov (United States)

    Raposinho, Paula D; Xavier, Catarina; Correia, João D G; Falcão, Soraia; Gomes, Paula; Santos, Isabel

    2008-03-01

    Early detection of primary melanoma tumors is essential because there is no effective treatment for metastatic melanoma. Several linear and cyclic radiolabeled alpha-melanocyte stimulating hormone (alpha-MSH) analogs have been proposed to target the melanocortin type 1 receptor (MC1R) overexpressed in melanoma. The compact structure of a rhenium-cyclized alpha-MSH analog (Re-CCMSH) significantly enhanced its in vivo tumor uptake and retention. Melanotan II (MT-II), a cyclic lactam analog of alpha-MSH (Ac-Nle-cyclo[Asp-His-DPhe-Arg-Trp-Lys]-NH2]), is a very potent and stable agonist peptide largely used in the characterization of melanocortin receptors. Taking advantage of the superior biological features associated with the MT-II cyclic peptide, we assessed the effect of lactam-based cyclization on the tumor-seeking properties of alpha-MSH analogs by comparing the pharmacokinetics profile of the 99mTc-labeled cyclic peptide betaAla-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2 with that of the linear analog betaAla-Nle-Asp-His-DPhe-Arg-Trp-Lys-NH2 in melanoma-bearing mice. We have synthesized and coupled the linear and cyclic peptides to a bifunctional chelator containing a pyrazolyl-diamine backbone (pz) through the amino group of betaAla, and the resulting pz-peptide conjugates were reacted with the fac-[99mTc(CO)3]+ moiety. The 99mTc(CO)3-labeled conjugates were obtained in high yield, high specific activity, and high radiochemical purity. The cyclic 99mTc(CO)3-labeled conjugate presents a remarkable internalization (87.1% of receptor-bound tracer and 50.5% of total applied activity, after 6 h at 37 degrees C) and cellular retention (only 24.7% released from the cells after 5 h) in murine melanoma B16F1 cells. A significant tumor uptake and retention was obtained in melanoma-bearing C57BL6 mice for the cyclic radioconjugate [9.26 +/- 0.83 and 11.31 +/- 1.83% ID/g at 1 and 4 h after injection, respectively]. The linear 99mTc(CO)3-pz-peptide presented lower values for

  19. Diagnóstico del proceso de adquisiciones logísticas aeronáuticas a través del Portal de proveedores de la agencia de compras FAC

    OpenAIRE

    Sonia María Peña Rendón; Erika Juliana Estrada Villa

    2014-01-01

    La propuesta de mejora al Portal de Proveedores del Exterior de la Fuerza Aérea Colombiana, es un trabajo de investigación efectuado con el fin de fortalecer los canales de comunicación y reducir el tiempo de repuesta en el proceso logístico de abastecimientos, agilizando y optimizando la herramienta de adquisiciones de la Agencia de Compras de la FAC, de tal manera que se garantice la credibilidad del sistema ante los proveedores y la transparencia en el uso de la información. El artículo...

  20. The Previously Undetected Presence of Culex restuans (Diptera: Culicidae) in Central America, with Notes on Identification

    Science.gov (United States)

    1988-01-01

    geografica actualizada. Rev. Inv. Salud Publica (Mexico) 33: 11 I - 125. Heinemann, S.J. and J.N. Belkin. 1977. Collection records of the project...Mosquitoes of Middle America” 8. Central America: Belize (BH), Guatemala (GUA), El Salvador ( SAL ), Honduras (HON), Nicaragua (NI, NIC). Mosq. Syst...Culicidae). Ill. Nat. Hist. Surv. Biol. Notes 52, 50 pp. Vargas, L. 1956. Especies y distribucidn de mosquitos mexicanos no anofelinos. Rev. Instit. de

  1. Semiempirical study of the interacting potentials for H+ + CO and H+ + NO+

    International Nuclear Information System (INIS)

    Canuto, S.

    1983-01-01

    Semiempirical INDO molecular orbital calculations of the minimum energy path for the formation of HCO + , HOC + , HNO ++ and HON ++ from the proton reactions H + + CO and H + + NO + are presented. Energy barriers, geometry relaxations and stabilization energies are given. Comparisons with ab initio SCF (Self-Consistent Field) and CI (Configuration Interaction) calculations are performed in order to assess the reliability of the calculations. (Author) [pt

  2. Army Science Conference Proceedings, 12-15 June 1990, Volume 2: Principal Authors G-M

    Science.gov (United States)

    1990-07-30

    C. Measurement of the Refractive Indices of Fluoride Glasses Using Digital Refractometry II 333 Kyle, Dennis E. See Milhous, Wilbur K. II 543...Fluoride Glasses using Digital Refractometry (U) Hon C. Kwan, CPT, SC Steven S. Cotariu, CPT, IN US Army Photonics Research Cell united States Military...manner. We have applied Digital Refractometry to the measure- ment of the refractive index of four new fluoride glasses. Digital Refractometry is

  3. Qingping Straight Sword: The Last Remaining Chinese Sword System?

    Directory of Open Access Journals (Sweden)

    Stephan Berwick

    2012-07-01

    Full Text Available The following examination of classical Chinese straight sword (jian details the very rare Qingping straight sword system. The study meshes Chinese- and English-sourced research with a revealing interview (conducted by America’s senior Qingping disciples, Reza Momenan and Hon Lee with Lu Junhai—the grandmaster of this unique sword system. The author presents Qingping system as perhaps the only known, complete Chinese sword system surviving from China’s pre-Rebulican era (1911-1949.

  4. Communication and Jamming BDA of OFDMA Communication Systems Using the Software Defined Radio Platform WARP

    Science.gov (United States)

    2015-03-01

    COMMUNICATION AND JAMMING BDA OF OFDMA COMMUNICATION SYSTEMS USING THE SOFTWARE DEFINED RADIO PLATFORM WARP THESIS Kate J. Yaxley, FLTLT, Royal... BDA OF OFDMA COMMUNICATION SYSTEMS USING THE SOFTWARE DEFINED RADIO PLATFORM WARP THESIS Presented to the Faculty Department of Electrical and...COMMUNICATION AND JAMMING BDA OF OFDMA COMMUNICATION SYSTEMS USING THE SOFTWARE DEFINED RADIO PLATFORM WARP THESIS Kate J. Yaxley, B.E. (Elec) Hons Div II

  5. Latin America Report, No. 2717.

    Science.gov (United States)

    1983-08-04

    and transporta- tion development. The composition of the delegation was the Hon. Fred Hunter, Mr. Alberto Espat, Mr. Telford Vernon, representing...committee when Deputy Joao Herman Neto (PMDB, Sao Paulo) expressed his amazement that General Venturini "is not telling us the truth." He suggested...success for several months and now a reality. What Gen Joao Figueiredo and his political aides sought to no avail through a thousand ruses has just

  6. A conversation with Geoff Watson

    OpenAIRE

    Beran, R. J.; Fisher, N. I.

    1998-01-01

    Geoffrey Stuart Watson, Professor Emeritus at Princeton University, celebrated his 75th birthday on December 3, 1996. A native Australian, his early education included Bendigo High School and Scotch College in Melbourne. After graduating with a B.A. (Hons.) from Melbourne University in December 1942, he spent the next few years, during and after World War II, doing research and teaching on applied mathematical topics. His wandering as a scholar began in 1947, when he became ...

  7. Monitoring of Viral Induced Cell Death Using Real Time Cell Analysis

    Science.gov (United States)

    2016-11-01

    Land Division David Thirkettle-Watts completed a BSc (Hons) in molecular genetics and molecular biology at the University of Western Australia...UWA) and a PhD in 2004. His PhD research involved the characterisation of the promoter regions of a family of soybean genes using molecular and...Berrimah Veterinary Laboratories, Darwin , NT (Gauci et al. 2016; Gauci et al. 2015a; Gauci et al. 2015b; McAllister et al. 2014); Gubala et al. 2016

  8. Automated Detection of HONcode Website Conformity Compared to Manual Detection: An Evaluation

    OpenAIRE

    Boyer, Célia; Dolamic, Ljiljana

    2015-01-01

    Background To earn HONcode certification, a website must conform to the 8 principles of the HONcode of Conduct In the current manual process of certification, a HONcode expert assesses the candidate website using precise guidelines for each principle. In the scope of the European project KHRESMOI, the Health on the Net (HON) Foundation has developed an automated system to assist in detecting a website?s HONcode conformity. Automated assistance in conducting HONcode reviews can expedite the cu...

  9. Browse Title Index

    African Journals Online (AJOL)

    Items 751 - 800 of 1000 ... M. D. Doumbia, A. Sidibé, A. Bagayoko, M. A. Diarra, A. Bationo, R. A. Kablan, R. S. Yost, L. R. Hossner, F. M. Hons. Vol 22 (2014): Supplement, Recovery of amiRNA3-PARP1 transgenic maize plants using a binary vector having the biosafe PMI Gene, Abstract PDF. JM Matheka, AO Rasha, S Anami, ...

  10. Compressive Information Extraction: A Dynamical Systems Approach

    Science.gov (United States)

    2016-01-24

    significantly benefit society. Systems endowed with activity analysis capabilities can prevent crime, allow elderly people to continue living independently...keynote speaker at the 2014 IEEE International Conference on Distributed Smart Cameras. 9 2.5 Transitions The theoretical framework developed under...FBI Deputy Director, June 2013) and the Hon. Theresa May (U.K. Home Secretary, Sept. 2014). It was also covered in a N.Y. Times article that appeared

  11. The Third Wave of Democratization in Indonesia

    Science.gov (United States)

    2000-03-01

    Dewan Perwakilan Rakyat (House of the Representatives) augmented by delegates from the regional territories and the groups in accordance with...unlimited THE THIRD WAVE OF DEMOCRATIZATION IN INDONESIA Azizan bin Md Delin Lieutenant Colonel, Malaysian Army LL B. (Hons), UiTM, Malaysia , 1996...Article 2(1) of the 1945 Constitution reads: "The Majelis Permusyawaratan Rakyat (People’s Consultative Assembly) shall consist of members of the

  12. The Effects of Employing HVM on C-130 Aircraft at WR-ALC to Aircraft Availability

    Science.gov (United States)

    2011-06-01

    processes of numerous commercial companies such as American Airlines, TIMCO, the Royal Canadian Air Force, and Hon Furniture to determine how and why...commercial industry best practices that best achieve higher labor burn rates and the challenges of implementing these practices into the traditional...Challenges According to Jerry Mobley, the HVM team in 2007 initiated the study and industrial analysis of the Maintenance, Repair, and Overhaul (MRO

  13. Cervical cytology screening - knowledge, attitudes and practice in a ...

    African Journals Online (AJOL)

    commonly reported facility where Pap tests were known to be done. The majority ... third of interviewees reported haVing had a Pap test. (37.2%; 95% Cl ... Ross Bailie. M.B. CH.8.• M.PHIL (M.C.H.), M.O. \\COMM. HEALTH). William Pick. M.a. CH.B.• M.MED.. O.T.M..&H.. O.P.H.. Dj Cooper, a.soc. SGt. BA HONS. PH.O. SAMJ.

  14. Quality of online information on type 2 diabetes: a cross-sectional study.

    Science.gov (United States)

    Weymann, Nina; Härter, Martin; Dirmaier, Jörg

    2015-12-01

    Evidence-based health information is a prerequisite for patients with type 2 diabetes to engage in self-management and to make informed medical decisions. The Internet is an important source of health information. In the present study, we systematically assessed formal quality, quality of decision support and usability of German and English language websites on type 2 diabetes. The search term 'type 2 diabetes' was entered in the two most popular search engines. Descriptive data on website quality are presented. Additionally, associations between website quality and affiliation (commercial vs. non-commercial), presence of the HON code quality seal and website traffic were explored. Forty-six websites were included. Most websites provided basic information necessary for decision-making, while only one website also provided decision support. Websites with a HON code had significantly better formal quality than websites without HON code. We found a highly significant correlation between usability and website traffic and a significant correlation between formal quality and website traffic. Most websites do not provide sufficient information to support patients in medical decision-making. Our finding that usability and website traffic are tightly associated is consistent with previous research indicating that design is the most important cue for users assessing website credibility. © The Author (2014). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  15. Surfing Behind a Boat: Quality and Reliability of Online Resources on Scaphoid Fractures.

    Science.gov (United States)

    Nassiri, Mujtaba; Mohamed, Osama; Berzins, Arvids; Aljabi, Yasser; Mahmood, Talat; Chenouri, Shojaeddin; O'Grady, Paul

    2016-10-01

    Patients seeking information and advice on treatment of scaphoid fractures unknowingly confront longstanding medical controversies surrounding the management of this condition. However, there are no studies specifically looking into the quality and reliability of online information on scaphoid fractures. We identified 44 unique websites for evaluation using the term "scaphoid fractures". The websites were categorized by type and assessed using the DISCERN score, the Journal of the American Medical Association (JAMA) benchmark criteria and the Health on the net (HON) code. The majority of websites were commercial (n = 13) followed by academic (n = 12). Only seven of the websites were HON certified. The mean DISCERN score was 43.8. Only 4 websites scored 63 or above representing excellent quality with minimal shortcomings but 13 websites scored 38 or below representing poor or very poor quality. The mean JAMA benchmark criteria score was 2.2. The Governmental and Non-Profit Organizations category websites had the highest mean JAMA benchmark score. The websites that displayed the HON-code seal had higher mean DISCERN scores and higher mean JAMA benchmark scores compared to websites that did not display the seal. Good quality health information is certainly available on the Internet. However, it is not possible to predict with certainty which sites are of higher quality. We suggest clinicians should have a responsibility to educate their patients regarding the unregulated nature of medical information on the internet and proactively provide patients with educational resources and thus help them make smart and informed decisions.

  16. Publication rates and characteristics of undergraduate medical theses in New Zealand.

    Science.gov (United States)

    Al-Busaidi, Ibrahim Saleh; Alamri, Yassar

    2016-09-23

    Publication in peer-reviewed journals is widely regarded as the preferred vehicle for research dissemination. In New Zealand, the fate and publication rates of theses produced by medical students is unknown. The aim of this study was to examine the frequency and characteristics of publications derived from research conducted by Bachelor of Medical Sciences (BMedSc(Hons)) students at the three campuses of the University of Otago Medical School, New Zealand. A total of 153 BMedSc(Hons) theses accepted at the Otago Medical School during the period of January 1995 to December 2014 were analysed. Using standardised search criteria, PubMed and Google Scholar databases were searched in October 2015 to examine the number and characteristics of publications. Overall, 50 (32.7%) out of 153 included theses resulted in 81 scientific publications. Ten (12.3%) publications featured in Australasian journals. The majority of publications were original articles (84%), with pathology and molecular biology (19%) being the most common research area. Although they did not reach statistical significance, publications in higher impact factor journals trended towards having a senior first author as opposed to a student first author (p=0.06). Although higher than reported figures from previous studies, publication rates of BMedSc(Hons) theses remain lower than expected. To improve our understanding of medical student publishing in New Zealand, formal examination of the factors hindering medical students from publishing their theses is imperative.

  17. Quality of web-based information on social phobia: a cross-sectional study.

    Science.gov (United States)

    Khazaal, Yasser; Fernandez, Sebastien; Cochand, Sophie; Reboh, Isabel; Zullino, Daniele

    2008-01-01

    The objective of the study is to evaluate the quality of web-based information on social phobia and to investigate particular quality indicators. Two keywords, "Social phobia" and "Social Anxiety Disorder", were entered into five popular World Wide Web search engines. Websites were assessed with a standardized proforma designed to rate sites on the basis of accountability, presentation, interactivity, readability, and content quality. "Health On the Net" (HON) quality label and DISCERN scale scores aiding people without content expertise to assess quality of written health publication were used to verify their efficiency as quality indicators. This study evaluates the quality of web-based information on social phobia. On the 200 identified links, 58 were included. On the basis of outcome measures, the overall quality of the sites turned out to be poor. DISCERN and HON label were indicators of good quality indicators. Accountability criteria were poor indicators of site quality. Although social phobia education Websites for patients are common, educational material highly varies in quality and content. There is a need for better evidence-based information about social phobia on the Web and a need to reconsider the role of accountability criteria as indicators of site quality. Clinicians should advise patients of the HON label and DISCERN as useful indicators of site quality. (c) 2007 Wiley-Liss, Inc.

  18. Mechanism and kinetics for ammonium dinitramide (ADN) sublimation: a first-principles study.

    Science.gov (United States)

    Zhu, R S; Chen, Hui-Lung; Lin, M C

    2012-11-08

    The mechanism for sublimation of NH(4)N(NO(2))(2) (ADN) has been investigated quantum-mechanically with generalized gradient approximation plane-wave density functional theory calculations; the solid surface is represented by a slab model and the periodic boundary conditions are applied. The calculated lattice constants for the bulk ADN, which were found to consist of NH(4)(+)[ON(O)NNO(2)](-) units, instead of NH(4)(+)[N(NO(2))(2)](-), agree quite well with experimental values. Results show that three steps are involved in the sublimation/decomposition of ADN. The first step is the relaxation of the surface layer with 1.6 kcal/mol energy per NH(4)ON(O)NNO(2) unit; the second step is the sublimation of the surface layer to form a molecular [NH(3)]-[HON(O)NNO(2)] complex with a 29.4 kcal/mol sublimation energy, consistent with the experimental observation of Korobeinichev et al. (10) The last step is the dissociation of the [H(3)N]-[HON(O)NNO(2)] complex to give NH(3) and HON(O)NNO(2) with the dissociation energy of 13.9 kcal/mol. Direct formation of NO(2) (g) from solid ADN costs a much higher energy, 58.3 kcal/mol. Our calculated total sublimation enthalpy for ADN(s) → NH(3)(g) + HON(O)NNO(2)) (g), 44.9 kcal/mol via three steps, is in good agreement with the value, 42.1 kcal/mol predicted for the one-step sublimation process in this work and the value 44.0 kcal/mol computed by Politzer et al. (11) using experimental thermochemical data. The sublimation rate constant for the rate-controlling step 2 can be represented as k(sub) = 2.18 × 10(12) exp (-30.5 kcal/mol/RT) s(-1), which agrees well with available experimental data within the temperature range studied. The high pressure limit decomposition rate constant for the molecular complex H(3)N···HON(O)NNO(2) can be expressed by k(dec) = 3.18 × 10(13) exp (-15.09 kcal/mol/RT) s(-1). In addition, water molecules were found to increase the sublimation enthalpy of ADN, contrary to that found in the ammonium

  19. Diagnóstico del proceso de adquisiciones logísticas aeronáuticas a través del Portal de proveedores de la agencia de compras FAC

    Directory of Open Access Journals (Sweden)

    Sonia María Peña Rendón

    2014-01-01

    Colombiana, es un trabajo de investigación efectuado con el fin de fortalecer los canales de comunicación y reducir el tiempo de repuesta en el proceso logístico de abastecimientos, agilizando y optimizando la herramienta de adquisiciones de la Agencia de Compras de la FAC, de tal manera que se garantice la credibilidad del sistema ante los proveedores y la transparencia en el uso de la información. El artículo se enfocó en determinar las falencias del sistema, mediante la evaluación del Portal por parte de proveedores y usuarios internos, así como el análisis a la documentación sobre novedades del sistema, arrojando como resultado que las principales problemáticas en el portal de proveedores se derivan de la falta de conocimiento en el manejo de la página web y la funcionalidad del sistema por ausencia de transacciones que permiten realizar operaciones en las cotizaciones.

  20. Cauda equina syndrome: assessing the readability and quality of patient information on the Internet.

    Science.gov (United States)

    O'Neill, Shane Ciaran; Baker, Joseph Frederick; Fitzgerald, Conall; Fleming, Christina; Rowan, Fiachra; Byrne, Damien; Synnott, Keith

    2014-05-01

    A readability and quality control Internet-based study using recognized quality scoring systems. To assess the readability and quality of Internet information relating to cauda equina syndrome accessed through common search engines. Access to health-related Internet information has increased dramatically during the past decade. A significant proportion of this information has been demonstrated to be set at too high a level for general comprehension. Despite this, searching for health-related information is now the third most popular online activity. A total of 125 cauda equina syndrome Web sites were analyzed from the 5 most popular Internet search engines: Google, Bing, Yahoo, Ask, and AOL. Web site authorship was classified: academic, physician, medico-legal, commercial, or discussion/social media. Readability of each Web site was assessed using the Flesch Reading Ease score, the Flesch-Kincaid grade level, and the Gunning Fog Index. Quality was calculated using the DISCERN instrument and The Journal of the American Medical Association benchmark criteria. The presence of HON-code certification was also assessed. Fifty-two individual Web sites were identified and assessed. The majority of Web sites were academic or physician compiled (53.8%; 28/52); however, a significant minority of Web sites were medico-legal related (19.2%; 10/52). Just 13.5% (7/52) of Web sites were at or below the recommended sixth-grade readability level. HON-code certified Web sites achieved significantly greater DISCERN (P = 0.0006) and The Journal of the American Medical Association (P = 0.0002) scores. Internet information relating to cauda equina syndrome is of variable quality and largely set at an inappropriate readability level. Given this variability in quality, health care providers should direct patients to known sources of reliable, readable online information. Identification of reliable sources may be aided by known markers of quality such as HON-code certification.

  1. The quality and readability of online consumer information about gynecologic cancer.

    Science.gov (United States)

    Sobota, Aleksandra; Ozakinci, Gozde

    2015-03-01

    The Internet has become an important source of health-related information for consumers, among whom younger women constitute a notable group. The aims of this study were (1) to evaluate the quality and readability of online information about gynecologic cancer using validated instruments and (2) to relate the quality of information to its readability. Using the Alexa Rank, we obtained a list of 35 Web pages providing information about 7 gynecologic malignancies. These were assessed using the Health on the Net (HON) seal of approval, the Journal of the American Medical Association (JAMA) benchmarks, and the DISCERN instrument. Flesch readability score was calculated for sections related to symptoms and signs and treatment. Less than 30% of the Web pages displayed the HON seal or achieved all JAMA benchmarks. The majority of the treatment sections were of moderate to high quality according to the DISCERN. There was no significant relationship between the presence of the HON seal and readability. Web pages achieving all JAMA benchmarks were significantly more difficult to read and understand than Web pages that missed any of the JAMA benchmarks. Treatment-related content of moderate to high quality as assessed by the DISCERN had a significantly better readability score than the low-quality content. The online information about gynecologic cancer provided by the most frequently visited Web pages is of variable quality and in general difficult to read and understand. The relationship between the quality and readability remains unclear. Health care providers should direct their patients to reliable material online because patients consider the Internet as an important source of information.

  2. [How does our specialty present itself on the Internet?].

    Science.gov (United States)

    Rechenberg, U; Josten, C; Grüner, S; Klima, S

    2013-08-01

    The huge amount of information on the internet about orthopaedic and trauma surgical issues is very often unclear and hard to control in reliability, autonomy and expertise. The aim of this work is to evaluate German-speaking internet sites with orthopaedic and trauma surgical contents. Over a period of two months (from May to June) in 2012 different websites about 20 common orthopaedic and trauma surgical diseases were analysed on the internet by Google search engine. The first ten search results were evaluated for the HON code principles (Health On the Net Foundation). Furthermore there was an evaluation about qualification of the first 50 websites. The best 1,000 placed websites on Google were analysed for the authoritative value: academic, commercial, media, non-medical, physicians, non-profit and miscellaneous. Only 194 from 200 websites could be evaluated by the HON code principles. Overall 188 websites complied the principle of transparency, followed by privacy with 150 sites and authoritative with 134 sites. Only 90 websites give information about financial disclosure. Medical articles of the website Wikipedia appear most frequently. In the second part of this work it is shown that non-profit sites and sites by physicians are the most frequent. The fewest results are given by academic and commercial sites with 93 and 85 online hits. In summary, it is shown that most of the websites about medical information have inadequate quality. This statement is in accord with some U. S. American publications. It is clear that Wikipedia has a top-ranking on the internet when it is about medical information. Wikipedia almost achieves all of the HON code principles. It is possible to give better medical online information about orthopaedic and trauma surgical issues published by professionals. Georg Thieme Verlag KG Stuttgart · New York.

  3. Analysis of readability and quality of web pages addressing both common and uncommon topics in pediatric surgery.

    Science.gov (United States)

    Adorisio, Ottavio; Silveri, Massimiliano; Rivosecchi, Massimo; Tozzi, Alberto Eugenio; Scottoni, Federico; Buonuomo, Paola Sabrina

    2012-06-01

    The quality medical information on Internet is highly variable. The aim of this study is to determine if Web pages addressing four common pediatric surgical topics (CT) and four uncommon pediatric surgical topics (UT) differ significantly in terms of quality and/or characteristics. We performed an Internet search regarding four CT, addressing more frequent clinical conditions with an incidence≤1:1.500 children (inguinal hernia, varicocele, umbilical hernia, and phimosis) and four UT addressing less frequent clinical conditions with an incidence≥1:1.500 children (anorectal malformation, intestinal atresia, gastroschisis, and omphalocele), using a popular search engine (Google). We evaluated readability with the Flesch reading ease (FRE) and the Flesch-Kincaid grade (FKG) and quality of content using the site checker of the HON Code of Conduct (HON code) for each website. In this study, 30/40 websites addressing CT versus 33/50 addressing UT responded to our criteria. No differences statistically significant in advertisements between the two groups were found (15 vs. 16%) (p>0.05). No differences were found in terms of time from last update, owner/author type, financial disclosure, accreditation, or advertising. CT had higher quality level according to the HON code (6.54±1.38 vs. 5.05±1.82) (p0.05). The mean FKG was 8.1±1.9 for CT versus 8±1.9 for UT (p>0.05). Websites devoted to pediatric surgical topics have higher readability and quality information for disease diagnosis and natural history. Otherwise, the quality of pediatric surgical information on the Internet is high for CT and UT. A high reading level is required to use these resources. Copyright © 2012 by Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  4. Chiropractic wellness on the web: the content and quality of information related to wellness and primary prevention on the Internet

    Directory of Open Access Journals (Sweden)

    Evans Marion

    2011-02-01

    Full Text Available Abstract Background The Internet has become a common source of information for patients wishing to learn about health information. Previous studies found information related to back pain poor and often contradictory to current guidelines. Wellness has become a common topic in the field of chiropractic and accrediting agencies have standards on delivery of wellness-based content in college curricula as well as directives for clinical applications. The purpose of this study was to evaluate the quality of the information on the Internet using the terms "chiropractic wellness," or "wellness chiropractic". Methods Five commonly used search engines were selected and the first 10 sites found using the strategy above were evaluated by two raters. Demographic assessments of the sites were made along with whether they were Health on the Net Foundation (HON certified, contained standard wellness content, mentioned any Healthy People Focus Areas, and other chiropractic topics. Kappa statistics compared inter-rater agreement. Results Potential patients appeared to be the audience 87% of the time and a private doctor of chiropractic appeared to be the typical site owner. The sites usually promoted the provider. No sites displayed HON certification logo nor did any appear to meet the HON certification criteria. Twenty-six sites (55% promoted regular physical activity in some manner and 18 (38% had information on health risks of tobacco. Four (9% had mental health or stress-reduction content but none had information supportive of vaccination. Some had information contradictory to common public health measures. Conclusions Patients searching the Internet for chiropractic wellness information will often find useless information that will not help them maintain health or become well. Most simply market the chiropractic practice or allow for a patients to provide personal information in exchange for more 'wellness' information. More research should be done on how

  5. Heritage Forward: The Central Command Historical-Cultural Advisory Group

    Science.gov (United States)

    2013-10-22

    other provision of law , no person shall be subject to any penalty for failing to comply with a collection of information if it does not display a...ol Defame (000] together m an «Hon to :tqprmt cultural and heritage WWriawi ol m.iit»r> Benenne I .»»«rating ■■■■«■i BUtufepf tneUeMeri&aHi...ROTC curriculum dealing with the Law of Warfare, in which the issue of Cultural Property Protection is addressed with reference to the U.S

  6. Disease: H00377 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00377 Rabies Rabies is an old zoonotic disease which has been known for more than...om it. Dogs are the major vectors. Rabies affects the central nervous system and causes fatal encephalomyeli...Africa die every year due to rabies. Infectious disease ... Rabies virus (RABV) [GN:T40022] ... Rabies vaccine [DR:D06504 D05248] Rabies... ... Yousaf MZ, Qasim M, Zia S, Khan Mu, Ashfaq UA, Khan S ... TITLE ... Rabies molecular virology, diagnosis, p... ... Leung AK, Davies HD, Hon KL ... TITLE ... Rabies: epidemiology, pathogenesis, and prophylaxis. ... JOURNAL ... Adv Ther 24:1340-7 (2007) DOI:10.1007/BF02877781

  7. JPRS Report, Near East & South Asia, India

    Science.gov (United States)

    1991-08-06

    macroeconomic unbal - the Government. Much will depend on how far India is ances. The team will leave as soon as New Delhi concurs, prepared to tighten its belt...Dr. Singh said "commitments should be hon- justice? Mr. Singh saw no contractions. The real growth oured." of an economy could not be assessed only by...system to WEEK something to this effect: "We are not able to increase the scope of export growth . To this effect we will bring down prices because the

  8. NUTRICIÓN MINERAL CON N, P Y K EN LA SIMBIOSIS HONGOS MICORRIZÓGENOS-TOMATE (Lycopersicon esculentum Mill.) EN FERRALSOLS

    OpenAIRE

    Desirée Llonín; N. Medina

    2002-01-01

    Se evaluó el efecto de diferentes relaciones de nutrientes con N, P y K y la inoculación con dos cepas de hongos micorrízicos arbusculares-HMA- (G. clarum y G. fasciculatum), como fuentes de suministro de nutrientes aplicadas solas o en combinación, en fase de campo, sobre los incrementos de los rendimientos y la absorción de nutrientes. Para ello se determinaron el rendimiento del cultivo, la absorción de nutrientes y la colonización por HMA. Los resultados indican que la inoculación con hon...

  9. Interview with Bradley Quinn

    OpenAIRE

    Clarke, Sarah E. Braddock; Quinn, Bradley

    2012-01-01

    Sarah E. Braddock Clarke is an author, curator and consultant who lectures at University College Falmouth in Cornwall, where she works on the Fashion Design and\\ud Performance Sportswear Design B.A. (Hons) Degrees. Co-author of SportsTech and coauthor of Techno Textiles 1 and 11, Braddock Clarke is a leading expert in the field of\\ud fashion and performance sportswear. Her research focuses on emerging technologies and new materials, and explores the impact of digital media on textiles created...

  10. Reconfigurable computing the theory and practice of FPGA-based computation

    CERN Document Server

    Hauck, Scott

    2010-01-01

    Reconfigurable Computing marks a revolutionary and hot topic that bridges the gap between the separate worlds of hardware and software design- the key feature of reconfigurable computing is its groundbreaking ability to perform computations in hardware to increase performance while retaining the flexibility of a software solution. Reconfigurable computers serve as affordable, fast, and accurate tools for developing designs ranging from single chip architectures to multi-chip and embedded systems. Scott Hauck and Andre DeHon have assembled a group of the key experts in the fields of both hardwa

  11. Feminismens skilda erfarenheter : Problematiken att kombinera islam och feminism för muslimska kvinnor i Sverige

    OpenAIRE

    Malmberg, Erik

    2016-01-01

    Till följd av att en muslimsk kvinna misshandlades i en förort till Stockholm på grund av att hon bar slöja, genomfördes den politiska manifestationen Hijabuppropet. Denna manifestation resulterade i att kvinnor uppmanades att beslöja sig i syfte att visa solidaritet för den misshandlade kvinnan, och muslimska kvinnor som en marginaliserad samhällsgrupp. Agerandet möttes med en stark kritik från bland annat den svenska kvinnorörelsen som menade att slöjan är anti-feministisk och representerar...

  12. Sustainability of scholarly information

    CERN Document Server

    Chowdhury, G G

    2015-01-01

    Professor Gobinda Chowdhury BSc Hons, MSc, PhD, FCLIP is Professor in Information Science at iSchool@northumbria, and Head of the Department of Mathematics and Information Sciences at Northumbria University. Before joining Northumbria University he was a Professor and Director of the Centre for Information and Knowledge Management at the University of Technology Sydney, Australia. For over 25 years he has worked as an academic and researcher in information science in different parts of the world including Asia, Africa, Europe and Australia. For the past few years he has been actively involved

  13. Can we do it?

    International Nuclear Information System (INIS)

    Locheed, T.A.

    1993-01-01

    One wonders how a facility will cope with the new Clean Air Act Amendments (CAAA). Environmental engineers working in large companies' facilities and in corporate engineering groups already have an idea of how to comply with the regulations for chemical plant equipment leaks. (In fact, the rules will also affect process bins, wastewater, transfer and storage.) But those who work for smaller companies or who have assignments not directly tied to environmental affairs may not have access to the latest thinking on compliance. One of the first challenges in becoming aware of the CAAA regulations is learning the new language, which consists of acronyms, some containing other acronyms. NESHAP, for example, stands for national emissions standards for hazardous air pollutants. Prior to the CAAA, NESHAPs applied to a few specific chemicals, such as benzene. Now the proposed rules establish a HON, a hazardous organic NESHAP. According to David Gustafson, environmental air issues manager with Dow Chemical Company in Midland, MI, the HON mandates broader controls for a very large group of chemicals, including many of those made by the synthetic organic chemicals manufacturing industry (SOCMI)

  14. A modernização do Arquivo Nacional: uma análise comparativa de 1958-1963 e 1980-1986

    Directory of Open Access Journals (Sweden)

    Rosale de Mattos Souza

    2015-06-01

    Full Text Available Este artigo analisa os fatores que contribuíram para o desenvolvimento e modernização do Arquivo Nacional do Brasil, nos períodos de 1958-1963 e 1980-1986, dando ênfase aos modelos administrativos adotados e trajetórias. Analisa os seguintes subtemas: relações do Arquivo Nacional do Brasil com a Administração Pública Federal, do ponto de vista documental, estrutura organizacional, legislação, orçamento, instalações físicas, recursos humanos e tratamento técnico. Da metodologia apresenta-se quadro comparativo das ações desenvolvidas naquelas duas gestões. Constatou-se o início de uma conscientização arquivística no país com a administração do prof. José Honório Rodrigues: a década de 1960, como marco divisório para a administração do Arquivo Nacional, no sentido de dar à instituição um papel mais dinâmico. A administração da drª. Celina Moreira Franco, nos anos 1980, procurou alterar a situação do quadro de deficiências institucional, diagnosticada por José Honório Rodrigues.

  15. Adult orthodontics: a quality assessment of Internet information.

    Science.gov (United States)

    McMorrow, Siobhán Mary; Millett, Declan T

    2016-09-01

    This study evaluated the quality, reliability and readability of information on the Internet on adult orthodontics. A quality assessment of adult orthodontic websites. Postgraduate Orthodontic Unit, Cork University Dental School and Hospital, Cork, Ireland. An Internet search using three search engines (Google, Yahoo and Bing) was conducted using the terms ('adult orthodontics' and 'adult braces'). The first 50 websites from each engine and under each search term were screened and exclusion criteria applied. Included websites were then assessed for quality using four methods: the HON seal, JAMA benchmarks, the DISCERN instrument and the LIDA tool. Readability of included websites was assessed using the Flesch Reading Ease Score (FRES). Only 13 websites met the inclusion criteria. Most were of US origin (n = 8; 61%). The authors of the websites were dentists (n = 5; 39%), professional organizations (n = 2; 15%), past patients (n = 2; 15%) and unspecified (n = 4; 31%). Only 1 website displayed the HON seal and three websites contained all JAMA benchmarks. The mean overall score for DISCERN was 3.9/5 and the mean total LIDA score was 115/144. The average FRES score was 63.1/100. The number of informative websites on adult orthodontics is low and these are of moderate quality. More accurate, high-quality Internet resources are required on adult orthodontics. Recommendations are made as to how this may be achieved.

  16. Machine learning approach for automatic quality criteria detection of health web pages.

    Science.gov (United States)

    Gaudinat, Arnaud; Grabar, Natalia; Boyer, Célia

    2007-01-01

    The number of medical websites is constantly growing [1]. Owing to the open nature of the Web, the reliability of information available on the Web is uneven. Internet users are overwhelmed by the quantity of information available on the Web. The situation is even more critical in the medical area, as the content proposed by health websites can have a direct impact on the users' well being. One way to control the reliability of health websites is to assess their quality and to make this assessment available to users. The HON Foundation has defined a set of eight ethical principles. HON's experts are working in order to manually define whether a given website complies with s the required principles. As the number of medical websites is constantly growing, manual expertise becomes insufficient and automatic systems should be used in order to help medical experts. In this paper we present the design and the evaluation of an automatic system conceived for the categorisation of medical and health documents according to he HONcode ethical principles. A first evaluation shows promising results. Currently the system shows 0.78 micro precision and 0.73 F-measure, with 0.06 errors.

  17. Evaluation of websites that contain information relating to malaria in pregnancy.

    Science.gov (United States)

    Hamwela, V; Ahmed, W; Bath, P A

    2018-04-01

    The study identified available websites on malaria in pregnancy on the World Wide Web and sought to evaluate their readability and information quality. A purposeful sample of websites were selected which provided information on Malaria in pregnancy. A total of 31 websites were identified from searches using Google, Yahoo and Bing search engines. Two generic tools (Discern and HON), one specific tool designed to assess information quality of malaria in pregnancy and readability tests (Flesch Reading Ease and Flesh-Kincaid Grade level) were used to evaluate the websites. Most of the websites scored below 50% with the HON Code tool, with most lacking information on the symptoms. One website scored over 70 with the reading ease with two (2) achieving a score of 7 for the reading level test. The readability of the websites was too advanced for an ordinary consumer. The results of this study indicated that the information quality of malaria in pregnancy websites varied from fair to medium. It was also found that the readability of the websites was too advanced for an ordinary consumer. These findings suggest that most websites are not comprehensive in addressing all the relevant aspects of malaria in pregnancy. Copyright © 2018 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  18. All-optical bidirectional neural interfacing using hybrid multiphoton holographic optogenetic stimulation.

    Science.gov (United States)

    Paluch-Siegler, Shir; Mayblum, Tom; Dana, Hod; Brosh, Inbar; Gefen, Inna; Shoham, Shy

    2015-07-01

    Our understanding of neural information processing could potentially be advanced by combining flexible three-dimensional (3-D) neuroimaging and stimulation. Recent developments in optogenetics suggest that neurophotonic approaches are in principle highly suited for noncontact stimulation of network activity patterns. In particular, two-photon holographic optical neural stimulation (2P-HONS) has emerged as a leading approach for multisite 3-D excitation, and combining it with temporal focusing (TF) further enables axially confined yet spatially extended light patterns. Here, we study key steps toward bidirectional cell-targeted 3-D interfacing by introducing and testing a hybrid new 2P-TF-HONS stimulation path for accurate parallel optogenetic excitation into a recently developed hybrid multiphoton 3-D imaging system. The system is shown to allow targeted all-optical probing of in vitro cortical networks expressing channelrhodopsin-2 using a regeneratively amplified femtosecond laser source tuned to 905 nm. These developments further advance a prospective new tool for studying and achieving distributed control over 3-D neuronal circuits both in vitro and in vivo.

  19. Nuclear Waste Issues. Hearings before the Subcommittee on Energy and Power of the Committee on Energy and Commerce, US House of Representatives, One Hundredth Congress, First Session, on H.R. 2888 and H.R. 2967, June 11, 1987

    International Nuclear Information System (INIS)

    Anon.

    1987-01-01

    Proceedings of the hearings before the Subcommittee on Energy and Power of the Committee on Energy and Commerce held on two separate dates as the first sessions on bills H.R. 2888 and H.R. 2967 are recorded here. These bills would suspend certain activities of the Department of Energy (DOE) under the Nuclear Waste Policy Act of 1982 and would establish a nuclear waste policy review commission and an office of the nuclear waste negotiator. The hearings on 11 June 1987 examined the DOE's proposal to build a monitored retrievable storage facility (MRS) in Tennessee on the site of the Clinch Breeder Reactor. The General Accounting Office has questioned the adequacy of the DOE's study that recommended building the MRS. Testimony was presented by representatives of the American Nuclear Council; Community and Economic Development Division, General Accounting Office; Wisconsin Radioactive Waste Review Board; Washington Nuclear Waste Board; Sierra Club; Department of Health and Environment, State of Tennessee; Texas Nuclear Waste Programs Office; the Nuclear Regulatory Commission and the DOE. The Governor of Washington, Hon. Marilyn Lloyd, and Hon. Bart Gordon presented testimony. The concerns of the testimony were that the DOE was not ready to build the MRS - not enough study had been done to merit spending hugh amounts of money. Testimony on the two bills was not very supportive of the bills as they had been sponsored

  20. Game Edukasi Mengenal Huruf Katakana dan Hiragana Berbasis Android

    Directory of Open Access Journals (Sweden)

    Agus Gede Adi Prayoga

    2015-12-01

    Full Text Available Japanese language is different from other language in general, because in its writing is using Katakana and Hiragana letter. The use of Japanese is in various need, especially in communication for example entertaining tourists. Japanese language learning in Indonesia facing several problems among other are lack of infrastructure in practicing and also boring atmosphere which make students having difficulty in learning. Educational game application for mobile device is a new learning method is considered as a tool to attract one’s interest to learn. Educational Games to Indentify Katakana and Hiragana Letter is created in order to help to overcome the difficulty in learning Japanese Language relate to mastery Katakana and Hiragana letter. Learning material which is implied in the game came from Ni Hon Go 1 and Ni Hon Go No Kyoukasho curriculum. Game have three learning features such as table, letter writing and guessing, there are also entertaining addition features. Based on questionnaire data result on 30 students having difficulty in learning Japanese language, as much as 60% of respondents say that the game was easily understood as a Japanese language learning media.

  1. Green provisioning of the traffic partition grooming in robust, reconfigurable and heterogeneous optical networks

    Science.gov (United States)

    Hou, Weigang; Yu, Yao; Song, Qingyang; Gong, Xiaoxue

    2013-01-01

    In recent years, various high-speed network architectures have been widespread deployed. Dense Wavelength Division Multiplexing (DWDM) has gained favor as a terabit solution. The optical circuit switching has also been provided for "sub-rate" aggregation. Such that, the granular types of demands tend to be diverse and must be evaluated. However, current dedicated optical networks do not offer sufficient flexibility to satisfy the requirements of demands with such wide range of granularities. The traffic grooming becomes a power-efficient one only when it does not utilize the aggregation of Coarse-Granularity (CG) demands. The waveband switching merely provides port-cost-effective connections for CG demands regardless of fine-granularity ones. Consequently, in this paper, we devise a heterogeneous grooming method called traffic partition grooming. It combines the power efficiency advantage of the traffic grooming under fine-granularity environment and the port savings advantage of the waveband switching under coarse-granularity environment to provide green provisioning. In addition, the optical virtual topology self-reconfigures along with various optimization objectives variation and has the robustness to determine the pre-unknown information. This paper is also the first work on investigating the issue of Robust, Reconfigurable and Heterogeneous Optical Networking (R2HON). The effective green provisioning and OPEX savings of our R2HON have been demonstrated by numerical simulations.

  2. Faxing Structures to the Moon: Freeform Additive Construction System (FACS)

    Science.gov (United States)

    Howe, A. Scott; Wilcox, Brian; McQuin, Christopher; Townsend, Julie; Rieber, Richard; Barmatz, Martin; Leichty, John

    2013-01-01

    Using the highly articulated All-Terrain Hex-Limbed Extra-Terrestrial Explorer (ATHLETE) robotic mobility system as a precision positioning tool, a variety of print head technologies can be used to 3D print large-scale in-situ structures on planetary surfaces such as the moon or Mars. In effect, in the same way CAD models can be printed in a 3D printer, large-scale structures such as walls, vaults, domes, berms, paving, trench walls, and other insitu derived elements can be FAXed to the planetary surface and built in advance of the arrival of crews, supplementing equipment and materials brought from earth. This paper discusses the ATHLETE system as a mobility / positioning platform, and presents several options for large-scale additive print head technologies, including tunable microwave "sinterator" approaches and in-situ concrete deposition. The paper also discusses potential applications, such as sintered-in-place habitat shells, radiation shielding, road paving, modular bricks, and prefabricated construction components.

  3. Selection of viable cell subpopulations from murine tumours using FACS

    International Nuclear Information System (INIS)

    Chaplin, D.J.; Durand, R.E.; Olive, P.L.

    1985-01-01

    The authors developed a technique which enables isolation of viable tumour cells subpopulation as a function of their distance from the blood supply. The basis for this separation procedure is that the fluorochrome, Hoechst 33342, as a result of its high avidity for cellular DNA, exhibits a marked diffusion/consumption gradient when it has to pass through several cell layers. As a result intravenous injection of Hoechst 33342 into tumour bearing animals, results in a heterogeneous straining pattern within the tumour with cells close to blood vessels being brightly fluorescent while those more distant are less intensely stained. Since these differences in staining intensity persist after tumour disaggregation, cells can be sorted into subpopulations on the basis of their fluorescence intensity using a fluorescence activated cell sorter. This technique offers the unique possibility of identifying the location of those cell subpopulations resistant to treatment with either radiation or chemotherapeutic drugs

  4. Planeación por escenarios en la FAC

    Directory of Open Access Journals (Sweden)

    Mikell Ibarra Fernández

    2007-01-01

    La prospectiva cree que el futuro se explica desde el presente, y éste a su vez del pasado, esta relación causa-efecto permite construir nuestro mañana, valiéndose del análisis de los factores sociales, económicos, culturales, ambientales y políticos que afectan el desarrollo histórico, Llevándonos a una visión sistémica v compleja del mundo. Construir el mañana tiene al ser humano y a sus instituciones como protagonistas de su propia historia

  5. Partial nephrectomy online: a preliminary evaluation of the quality of health information on the Internet.

    Science.gov (United States)

    Fast, Angela M; Deibert, Christopher M; Boyer, Celia; Hruby, Gregory W; McKiernan, James M

    2012-12-01

    What's known on the subject? and What does the study add? Patients are highly likely to access the Internet for health information, and studies have reported that inaccurate or low-quality information may alter patients' expectations and negatively impact informed decision-making. In a unique collaboration with the Health On the Internet (HON) Foundation, we evaluated the top 20 search results for the urology search term 'partial nephrectomy,' and identified the highest and lowest scoring criteria to increase awareness of areas of concern and improvement. To further evaluate the quality of information available on the Internet with regard to the management of localized renal cancer, we evaluated websites providing information on 'partial nephrectomy' in conjunction with the Health On the Internet (HON) Foundation. Many patients now utilize the Internet as a resource to provide further information on disease, treatments and outcomes, and health information on the Internet is largely unregulated. Inaccurate information may contribute to unrealistic expectations and dissatisfied patients. A google.com search identified the top 30 websites for the search term 'partial nephrectomy'. The HON Foundation evaluated each website according to the eight principles for Health on the Internet code of conduct (HONcode) certification and reported the overall frequency of certification, as well as individual website compliance with each of the principles. Overall, seven (23.3%) of 30 websites met the requirements of HONcode certification and an additional two (6.7%) websites were under review to maintain their certification based on updating their resources. The remaining 21 (70%) websites did not meet the standards for certification. The lowest performing criteria included proper citation of medical information and a clear distinction of advertising from editorial content. The low rate of HONcode compliance for these websites illustrates the poor quality of information that

  6. Maximising safety in the boiler house.

    Science.gov (United States)

    Derry, Carr

    2013-03-01

    Last month's HEJ featured an article, the second in our new series of guidance pieces aimed principally at Technician-level engineers, highlighting some of the key steps that boiler operators can take to maximise system performance and efficiency, and thus reduce running both costs and carbon footprint. In the third such article, Derry Carr, C.Env, I.Eng, BSc (Hons), M.I.Plant.E., M.S.O.E., technical manager & group gas manager at Dalkia, who is vice-chairman of the Combustion Engineering Association, examines the key regulatory and safety obligations for hospital energy managers and boiler technicians, a number of which have seen changes in recent years with revision to guidance and other documentation.

  7. Från tonåring till toppbloggare : En kvalitativ fallstudie om självpresentation och det personliga varumärket kommunicerat genom en blogg

    OpenAIRE

    Laricchia, Daniela

    2016-01-01

    Sammanfattning Detta är en fallstudie över en Sveriges mest välkända och framgångsrika bloggar – www.kenzas.se, driven av Kenza Zouiten. Syftet med studien var att ta reda på hur man via självpresentation genom en blogg kan bygga upp och skapa sig ett starkt personligt varumärke. De frågeställningar studien utgick ifrån var hur Kenza Zouiten väljer att framställa sig själv som person i skriven text och i bilder, samt huruvida det finns några skillnader i hur hon väljer att framställa sig själ...

  8. This common inheritance: 1995 annual report. Minutes of evidence

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-05-17

    The document records questions relating to progress on environmental issues and actions in the White Paper entitled `Our Common Inheritance` (published in 1990) and also serves as an update to the UK`s sustainable development strategy. Questions were answered by Rt. Hon. John Gummer, Secretary of State for the Environment, Mr Richard Duding, Director of Pollution Control and Wastes, and Mrs Kay Hunt, Sustainable Development and General Environmental Policy Coordination. Topics covered included: the proposed landfill levy and water pollution charging; water metering; abatement of carbon dioxide emissions after the year 2000; tax on fuel; promotion of combined heat and power; road transport policy; meetings of the `interdepartmental green Ministers`; meeting commitments under the Convention of Biological Diversity; mine water pollution; and the `Going for Green` campaign.

  9. Surfing for hip replacements: has the "internet tidal wave" led to better quality information.

    Science.gov (United States)

    Nassiri, Mujtaba; Bruce-Brand, Robert A; O'Neill, Francis; Chenouri, Shojaeddin; Curtin, Paul T

    2014-07-01

    This study aimed to determine the quality of information available on the internet regarding Total Hip Replacement (THR). The unique websites identified were categorised by type and assessed using the DISCERN score, the Journal of the American Medical Association (JAMA) benchmark criteria, and a novel (THR)-specific content score. The presence of the Health On the Net (HON) code, a reported quality assurance marker, was noted. Commercial websites predominate. Governmental & Non-Profit Organizations websites attained the highest DISCERN score. Sites that bore the HONcode seal obtained significantly higher DISCERN and THR content scores than those without the certification. Physicians should recommend the HONcode seal to their patients as a reliable indicator of website quality or, better yet, refer patients to sites they have personally reviewed. Copyright © 2014 Elsevier Inc. All rights reserved.

  10. National Program for Inspection of Non-Federal Dams. Souhegan River Watershed Dam Number 35 (NH 00435), NHWRB 175.21, Merrimack River Basin, New Ipswich, New Hampshire. Phase I Inspection Report.

    Science.gov (United States)

    1979-08-01

    left end of the service platform has spalled over a 12 inch by 4 inch area. This spalling is attributed to excessive concrete vibra- tion. A...reinforced rod on ton of service platform exposed for 12"’ 1-f f Irescenct- NKone notedl Hon n E, com r)-1 12"’ x I" on headwa . seer- S age flowing through...3 nL 3 o m W(\\ +4 X -. = 0 wix .- X a kD X-~ W-I)~ + 0 5 Z I-- wJ 0 - U) w X -n = -o-Xb \\ W -- ~U)~.I-+ + -L a " fJ f It 1.Z’ X - r X tO U- -w LLI- W

  11. Muusika : Kremer tuleb üllatama. Bartokiga Pariisis. Raimo Kangro CD kiitvad arvustused. Festivalikorraldajad ühendavad jõud. EOÜ kolmas tegevusaasta. Jüri Pärg 50 aastat laval. Harri Vasar 75. Ernesaksa nimelised stipendiumid / Heili Vaus-Tamm

    Index Scriptorium Estoniae

    Vaus-Tamm, Heili, 1961-

    2001-01-01

    Tartus ja Tallinnas annab kontserte Gidon Kremer ja tema orkester Kremerata Baltica. 30.XI toimus Pariisis Liszti saalis HonEst Quintette debüütkontsert, kus kanti ette Bela Bartoki kammerloomingut. Saksa muusikaajakirjad Fono Forum ning Piano News arvustavad Raimo Kangro hiljuti välja antud CDd. 11.XII kohtusid kultuuriministeeriumis süvamuusikafestivalide korraldajad. 7.XII tuli EMA orelisaalis kokku Eesti Orelisõprade Ühingu aastakoosolek, juhatuse esimees A.-P. Lattik. Jüri Pärg märkis soolokontserdiga 25.XII Estonia talveaias oma 70. sünnipäeva ja 50 lava-aastat. Estonia talveaias meenutatukse Harri Vasarat, kes saanuks 75. aastaseks. 15.XII antakse TÜ aulas traditsioonilisel jõulukontserdil üle tänavused Gustav Ernesaksa nimelised stipendiumid.

  12. Understanding the art of feminist pedagogy: facilitating interpersonal skills learning for nurses.

    Science.gov (United States)

    Lamont, Emma

    2014-05-01

    The purpose of this study is to explore feminist pedagogy integrated with facilitation skills. A pedagogy project was undertaken with students participating in the BSc (Hons) Nursing programme, whereby a module, "Interpersonal Skills for Nurses" was developed for 72 year 1 students. A feminist pedagogy involves employing the powers of diversity to create an environment where all students' voices are heard. It values the power of sharing to create a community of learners in which teachers and students share their talents, skills and abilities to enhance the learning of all (Chinn, 2001). An end of semester evaluation provided feedback which indicated this was a valuable module to teach year 1 student nurses. It highlighted that student nurses found the topic both interesting and relevant and felt it was taught in a way that promoted their personal development and identity as a nurse. © 2013.

  13. An introduction to thermodynamics and statistical mechanics

    CERN Document Server

    Saxena, A K

    2016-01-01

    An Introduction to Thermodynamics and Statistical Mechanics aims to serve as a text book for undergraduate hons.and postgraduate students of physics. The book covers First Law of Thermodynamics, Entropy and Second Law ofThermodynamics, Thermodynamic Relations, The Statistical Basis of Thermodynamics, Microcanonical Ensemble,Classical Statistical and Canonical Distribution, Grand Canonical Ensemble, Quantum Statistical Mechanics, PhaseTransitions, Fluctuations, Irreversible Processes and Transport Phenomena (Diffusion).SALIENT FEATURES:iC* Offers students a conceptual development of the subjectiC* Review questions at the end of chapters.NEW TO THE SECOND EDITIONiC* PVT SurfacesiC* Real Heat EnginesiC* Van der Waals Models (Qualitative Considerations)iC* Cluster ExpansioniC* Brownian Motion (Einstein's Theory)

  14. Theoretical study of the nucleophilic addition of oximes to the nitrile complexes trans-/cis-[ReCl4(NCCH3)2

    International Nuclear Information System (INIS)

    Klestova-Nadeeva, E. A.; Kuznetsov, M. L.; Dement'ev, A. I.

    2005-01-01

    The reaction of nucleophilic addition of oximes (HON=CRR 1 ) to organic nitriles coordinated in the rhenium complexes trans-/cis-[ReCl 4 (NCCH 3 ) 2 ] was theoretically studied by the Hartree-Fock and density functional theory (B3LYP) methods. The reaction mechanism involves (I) the initial change of the oxime conformation; (II) the formation of the orientation complex with the coordinated nitrile molecule, which transforms into a four-membered transition state; (III) the formation of the addition product in a less stable conformation; and (IV) the formation of the ultimate addition product. The calculations make it possible to interpret the activation of nitriles in terms of the activated complex theory as a result of stabilization of the transition state in going from the free to the coordinated nitrile [ru

  15. AEC authorizing legislation, fiscal year 1975. Part 3. Hearings before the Joint Committee on Atomic Energy, Congress of the United States, Ninety-Third Congress, Second Session on Physical Research and Regulatory, February 28, 1974

    International Nuclear Information System (INIS)

    1974-01-01

    This volume contains testimony on the proposed budget for the physical research program presented at public hearings of the Joint Committee on Atomic Energy on the proposed AEC authorizing legislation for fiscal year 1975. Atomic Energy Commission witnesses were Commissioner William O. Doub; Director of Regulation L. Manning Muntzing; Dr. Wolfgang K. H. Panofsky, Director, SLAC; Dr. John M. Teem, Assistant General Manager for Physical Research and Laboratory Coordination; and Dr. Robert R. Wilson, Director, NAL. Other witnesses included B. James Porter, Donald C. Gilbert, Hon. Sterling Cole, and Wyatt M. Rogers, Jr. Prepared statements, questions and answers, a letter from AEC Chairman Ray, and the report of the ad hoc panel on heavy-ion facilities are included. (U.S.)

  16. Development of a group work assessment pedagogy using constructive alignment theory.

    Science.gov (United States)

    Croy, Suzanne R

    2018-02-01

    The purpose of this paper is to explore group work assessment underpinned by constructive alignment theory to develop a new assessment pedagogy. A review was undertaken of an existing module 'Mental Health Nursing 1', with student nurses participating in the BSc (Hons) Nursing Programme. Constructive alignment theory requires teachers to adopt a deep approach to learning where module learning outcomes are aligned with the teaching environment and modes of assessment. As the module progressed, reviewing the Mental Health Nursing 1 module became an excellent opportunity to begin to understand how constructive alignment theory can inform a group work assessment pedagogy. Working using a constructively aligned assessment process became a valuable learning experience for the module leader whilst at the same time revealed a gap in the research around the impact of constructively aligned teaching and group work assessment. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. An evaluation on the effectiveness of Web 2.0 Startpages (Netvibes & Pageflakes) within NHS libraries.

    Science.gov (United States)

    McCormick, Carol; Pickard, Alison Jane

    2013-06-01

    Carol McCormick was Learning Resources Advisor in the library at James Cook University Hospital, South Teesside when she completed her BSc (Hons) Librarianship (Work Based Learning) degree at Northumbria University. She gained a 1st Class Honours and is now Learning Resources Librarian. Carol's dissertation formed part of a wider action research project into the provision of current awareness services at James Cook University Hospital. This article reports on the evaluation which was conducted after a Web 2.0 Startpage, or portal, had been introduced to improve access to current awareness information for all staff within the Trust. It is the second article in the Dissertations into practice series to examine the use of web-based tools to improve access to information for NHS staff. AM. © 2013 The authors. Health Information and Libraries Journal © 2013 Health Libraries Group.

  18. Qualidade da informação da internet disponível para pacientes em páginas em português Quality of internet information available to patients on websites in Portuguese

    Directory of Open Access Journals (Sweden)

    Adriana Del Giglio

    2012-12-01

    Full Text Available OBJETIVO: Pacientes e seus familiares frequentemente procuram na internet informações a respeito de suas doenças. Diabetes mellitus (DM, hipertensão arterial sistêmica (HAS e infarto agudo do miocárdio (IAM são muito prevalentes no Brasil, e informações sobre estas patologias são bastante procuradas na internet. Por isso, buscamos avaliar a qualidade da informação relacionada com estas doenças disponível em português na internet. MÉTODOS: Foram selecionadas as primeiras 20 páginas em português de cada uma das doenças escolhidas, através do algoritmo de busca do Google®. Como ferramentas para avaliar a qualidade da informação foram utilizados o Discern Questionnarie (DQ e o Health on Net (HON. Para saber se as informações eram adequadas, foram utilizadas as diretrizes (guidelines brasileiras e internacionais para as diferentes comorbidades. RESULTADOS: Ao avaliar o conteúdo das informações disponíveis, 45%, 95%, 85% das páginas continham, respectivamente, a definição de DM, HAS e IAM. Com relação ao diagnóstico e ao tratamento, somente 25% das páginas das três comorbidades apresentavam especificamente esta informação. Somente 15%, 20% e 10% das páginas tinham a certificação pelo HON, respectivamente. Em função do DQ, as páginas obtiveram notas maiores que 50% em 70% das páginas de DM, 65% nas de HAS e 55% nas de IAM. CONCLUSÃO: A informação disponível em português na internet sobre as três patologias escolhidas (DM, HAS e IAM é frequentemente inadequada e insuficiente.OBJECTIVE: Patients and their relatives often look for information about their diseases on the internet. Diabetes mellitus (DM, systemic arterial hypertension (SAH, and acute myocardial infarction (AMI are the most prevalent in Brazil, thus, information on these pathologies is extremely searched for on the internet. For this reason, this study attempted to evaluate the quality of information available in Portuguese on the web

  19. Quality of web-based information on bipolar disorder.

    Science.gov (United States)

    Morel, Vincent; Chatton, Anne; Cochand, Sophie; Zullino, Daniele; Khazaal, Yasser

    2008-10-01

    To evaluate web-based information on bipolar disorder and to assess particular content quality indicators. Two keywords, "bipolar disorder" and "manic depressive illness" were entered into popular World Wide Web search engines. Websites were assessed with a standardized proforma designed to rate sites on the basis of accountability, presentation, interactivity, readability and content quality. "Health on the Net" (HON) quality label, and DISCERN scale scores were used to verify their efficiency as quality indicators. Of the 80 websites identified, 34 were included. Based on outcome measures, the content quality of the sites turned-out to be good. Content quality of web sites dealing with bipolar disorder is significantly explained by readability, accountability and interactivity as well as a global score. The overall content quality of the studied bipolar disorder websites is good.

  20. Quality of web-based information on cannabis addiction.

    Science.gov (United States)

    Khazaal, Yasser; Chatton, Anne; Cochand, Sophie; Zullino, Daniele

    2008-01-01

    This study evaluated the quality of Web-based information on cannabis use and addiction and investigated particular content quality indicators. Three keywords ("cannabis addiction," "cannabis dependence," and "cannabis abuse") were entered into two popular World Wide Web search engines. Websites were assessed with a standardized proforma designed to rate sites on the basis of accountability, presentation, interactivity, readability, and content quality. "Health on the Net" (HON) quality label, and DISCERN scale scores were used to verify their efficiency as quality indicators. Of the 94 Websites identified, 57 were included. Most were commercial sites. Based on outcome measures, the overall quality of the sites turned out to be poor. A global score (the sum of accountability, interactivity, content quality and esthetic criteria) appeared as a good content quality indicator. While cannabis education Websites for patients are widespread, their global quality is poor. There is a need for better evidence-based information about cannabis use and addiction on the Web.

  1. Introducing 'The Diverse Nature of Defence Healthcare' university module for DMS personnel.

    Science.gov (United States)

    Carter, Chris; Blake, L

    2015-12-01

    Over the past 10 years the UK Defence Medical Services has deployed healthcare personnel to a variety of operational areas in support of UK Operations. The unique nature of every operational deployment, in conjunction with the wide variety of roles which healthcare staff undertake, necessitates bespoke educational preparation of the military healthcare force. This paper explores the creation and development of one of the four modules which comprise the BSc (Hons) in Defence Health Care studies, entitled 'The Diverse Nature of Defence Healthcare'. It demonstrates the unique contribution that the Defence School of Healthcare Education makes towards Generation and Preparation of the Force for deployment. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  2. First record of the Two-striped Box Crab Calappa bilineata Ng, Lai & Aungtonya, 2002 (Brachyura: Calappidae from St. Martin’s Island, Bangladesh

    Directory of Open Access Journals (Sweden)

    Muntasir Akash

    2017-01-01

    Full Text Available As part of survey of a BS (hons study tour conducted by the Department of Zoology, University of Dhaka, two specimens of box crab were caught with a beach seine net from the northern beach in front of the Hotel Prince Heaven (20038’07.50”N & 92019’34.68”E on new moon of 07th December 2012.  Those box crabs were identified as the Two Striped Box Crab Calappa bilineata Ng, Lai & Aungtonya, 2002 which is turned out as a new record for Bangladesh and a record for the northern part of the Bay of Bengal. 

  3. Investigation of environmental change on the Tega Lake based on lake sediment analysis. Pt. 2. Dating of sediment by the lead-210/cesium-137 method and environmental change detected by the diatom assemblage analysis

    International Nuclear Information System (INIS)

    Hamada, Takaomi

    1998-01-01

    Sediment collected in the Tega Lake was dated by lead-210/cesium-137 method and environmental change in the Tega Lake was investigated by analysis of diatom remain assemblages in the sediment. Dating of the lead-210/cesium-137 method proved that the surface 30 cm-thickness of sediment in the Tega Lake was deposited during the recent 50 years. Diatom remain assemblage change in the Hon-Tega Lake sediment started in the early half of 1960's and the changes is characterized decrease of Fragilaria construens, that does not prefer to inhabit eutrophic water, and increase of Cyclotella meneghiniana that prefers to inhabit eutrophic water. This diatom assemblage change indicates that the Tega Lake was eutrophicated, and probably suggests water pollution in the Tega Lake. It is detected that influence of residential development around the Tega Lake and reclaiming by drainage on the Tega Lake. (author)

  4. Judgement on Windscale

    International Nuclear Information System (INIS)

    Roberts, G.C.; White, I.F.

    1978-01-01

    A summary is given of the findings of the report on the Windscale Inquiry into the application by British Nuclear Fuels Limited for planning permission to establish a plant for reprocessing irradiated oxide nuclear fuels (The Windscale Inquiry. Report by the Hon. Mr. Justice Parker, 26 January 1978, Vol.1, Report and Annexes 3 to 5, HMSO). Particular attention is given to comments in the report on the ICRP and NRPB, radiation protection standards, and the risks associated with fuel reprocessing. The bases of the judgements made are given, together with Mr. Justice Parker's recommenda-tions for the setting of discharge limits, monitoring discharges and levels of environmental radioactivity, and the assessment of what constitutes a tolerable risk to the public. (U.K)

  5. Trade, investment and the environment

    International Nuclear Information System (INIS)

    Ward, H.; Brack, D.

    2000-01-01

    As liberalisation of global trade and investment accelerates, what happens to the environment? As the world heads for confrontation in Seattle, the questions intensify. Does foreign direct investment mean forsaking environmental protection? Or do multinational corporations export higher standards when they invest abroad? Can a powerful trading nation ban imports of tropical timber produced unsustainably? Should the World Trade Organisation take the views of industry or environmental groups into account when deciding? Must world trade rules be changed to accommodate environmental concerns? This book analyzes key issues in this increasingly controversial arena and includes contributions from Renato Ruggiero, former Director General of the World Trade Organization; The Rt Hon Brian Wilson MP, former UK Minister of Trade; Dr Magda Shahin, Deputy Assistant Minister of Foreign Affairs at the Egyptian Ministry of Foreign Affairs; Pradeep Mehta, Secretary General, Consumer Unity and Trust Society, India; and Dr Michel Potier, Head of the Economics Division at the OECD's Environment Directorate. (Author)

  6. Bank Customers Management System

    Directory of Open Access Journals (Sweden)

    Ebubeogu Amarachukwu Felix

    2015-08-01

    Full Text Available ABSTRACT The purpose of this project is in partial fulfilment of the requirements of Bachelor of Science Hon in Information Technology. The Design and development of this Bank customers Management system provides a more secured approach in managing bank customers information which strengthens the relationships between banks and their customers by providing the right solutions that uses a multi-level security to improve customer satisfaction. The technology used in developing this project is ASP.NET and the programming language used to develop this project is C and the IDE used is Microsoft Visual Studio 2013 professional in designing the front end while the back end uses Microsoft SQL Server 2012.

  7. Characterization and biotoxicity assessment of dissolved organic matter in RO concentrate from a municipal wastewater reclamation reverse osmosis system.

    Science.gov (United States)

    Sun, Ying-Xue; Gao, Yue; Hu, Hong-Ying; Tang, Fang; Yang, Zhe

    2014-12-01

    Reverse osmosis (RO) concentrate from municipal wastewater reclamation reverse osmosis (mWRRO) system containing organic compounds may associate with toxic risk, and its discharge might pose an environmental risk. To identify a basis for the selection of feasible technology in treating RO concentrates, the characteristics and biotoxicity of different fractions of dissolved organic matter (DOM) in RO concentrates from an mWRRO system were investigated. The results indicated that the hydrophilic neutrals (HIN), hydrophobic acids (HOA) and hydrophobic bases (HOB) accounted for 96% of the dissolved organic carbon (DOC) of the total DOM in the RO concentrate. According to the SEC chromatograph detected at 254 nm wavelength of UV, the DOM with molecular weight (MW) 1-3 kDa accounted for the majority of the basic and neutral fractions. The fluorescence spectra of the excitation emission matrix (EEM) indicated that most aromatic proteins, humic/fulvic acid-like and soluble microbial by-product-like substances existed in the fractions HOA and hydrophobic neutrals (HON). The genotoxicity and anti-estrogenic activity of the RO concentrate were 1795.6 ± 57.2 μg 4-NQOL(-1) and 2.19 ± 0.05 mg TAM L(-1), respectively. The HIN, HOA, and HOB contributed to the genotoxicity of the RO concentrate, and the HIN was with the highest genotoxic level of 1007.9 ± 94.8 μg 4-NQOL(-1). The HOA, HON, and HIN lead to the total anti-estrogenic activity of the RO concentrate, and HOA occupied approximately 60% of the total, which was 1.3 ± 0.17 mg TAM L(-1). Copyright © 2014 Elsevier Ltd. All rights reserved.

  8. Quality of internet-based decision aids for shoulder arthritis: what are patients reading?

    Science.gov (United States)

    Somerson, Jeremy S; Bois, Aaron J; Jeng, Jeffrey; Bohsali, Kamal I; Hinchey, John W; Wirth, Michael A

    2018-04-11

    The objective of this study was to assess the source, quality, accuracy, and completeness of Internet-based information for shoulder arthritis. A web search was performed using three common Internet search engines and the top 50 sites from each search were analyzed. Information sources were categorized into academic, commercial, non-profit, and physician sites. Information quality was measured using the Health On the Net (HON) Foundation principles, content accuracy by counting factual errors and completeness using a custom template. After removal of duplicates and sites that did not provide an overview of shoulder arthritis, 49 websites remained for analysis. The majority of sites were from commercial (n = 16, 33%) and physician (n = 16, 33%) sources. An additional 12 sites (24%) were from an academic institution and five sites (10%) were from a non-profit organization. Commercial sites had the highest number of errors, with a five-fold likelihood of containing an error compared to an academic site. Non-profit sites had the highest HON scores, with an average of 9.6 points on a 16-point scale. The completeness score was highest for academic sites, with an average score of 19.2 ± 6.7 (maximum score of 49 points); other information sources had lower scores (commercial, 15.2 ± 2.9; non-profit, 18.7 ± 6.8; physician, 16.6 ± 6.3). Patient information on the Internet regarding shoulder arthritis is of mixed accuracy, quality, and completeness. Surgeons should actively direct patients to higher-quality Internet sources.

  9. Trends in internet search activity, media coverage, and patient-centered health information after the FDA safety communications on surgical mesh for pelvic organ prolapse.

    Science.gov (United States)

    Stone, Benjamin V; Forde, James C; Levit, Valerie B; Lee, Richard K; Te, Alexis E; Chughtai, Bilal

    2016-11-01

    In July 2011, the US Food and Drug Administration (FDA) issued a safety communication regarding serious complications associated with surgical mesh for pelvic organ prolapse, prompting increased media and public attention. This study sought to analyze internet search activity and news article volume after this FDA warning and to evaluate the quality of websites providing patient-centered information. Google Trends™ was utilized to evaluate search engine trends for the term "pelvic organ prolapse" and associated terms between 1 January 2004 and 31 December 2014. Google News™ was utilized to quantify the number of news articles annually under the term "pelvic organ prolapse." The search results for the term "pelvic organ prolapse" were assessed for quality using the Health On the Net Foundation (HON) certification. There was a significant increase in search activity from 37.42 in 2010 to 57.75 in 2011, at the time of the FDA communication (p = 0.021). No other annual interval had a statistically significant increase in search activity. The single highest monthly search activity, given the value of 100, was August 2011, immediately following the July 2011 notification, with the next highest value being 98 in July 2011. Linear regression analysis of news articles per year since the FDA communication revealed r 2  = 0.88, with a coefficient of 186. Quality assessment demonstrated that 42 % of websites were HON-certified, with .gov sites providing the highest quality information. Although the 2011 FDA safety communication on surgical mesh was associated with increased public and media attention, the quality of relevant health information on the internet remains of poor quality. Future quality assurance measures may be critical in enabling patients to play active roles in their own healthcare.

  10. 'Can you recommend any good STI apps?' A review of content, accuracy and comprehensiveness of current mobile medical applications for STIs and related genital infections.

    Science.gov (United States)

    Gibbs, Jo; Gkatzidou, Voula; Tickle, Laura; Manning, Sarah R; Tilakkumar, Tilna; Hone, Kate; Ashcroft, Richard E; Sonnenberg, Pam; Sadiq, S Tariq; Estcourt, Claudia S

    2017-06-01

    Seeking sexual health information online is common, and provision of mobile medical applications (apps) for STIs is increasing. Young people, inherently at higher risk of STIs, are avid users of technology, and apps could be appealing sources of information. We undertook a comprehensive review of content and accuracy of apps for people seeking information about STIs. Search of Google Play and iTunes stores using general and specific search terms for apps regarding STIs and genital infections (except HIV), testing, diagnosis and management, 10 September 2014 to 16 September 2014. We assessed eligible apps against (1) 19 modified Health on The Net (HON) Foundation principles; and (2) comprehensiveness and accuracy of information on STIs/genital infections, and their diagnosis and management, compared with corresponding National Health Service STI information webpage content. 144/6642 apps were eligible. 57 were excluded after downloading. 87 were analysed. Only 29% of apps met ≥6 HON criteria. Content was highly variable: 34/87 (39%) covered one or two infections; 40 (46%) covered multiple STIs; 5 (6%) focused on accessing STI testing. 13 (15%) were fully, 46 (53%) mostly and 28 (32%) partially accurate. 25 (29%) contained ≥1 piece of potentially harmful information. Apps available on both iOS and Android were more accurate than single-platform apps. Only one app provided fully accurate and comprehensive information on chlamydia. Marked variation in content, quality and accuracy of available apps combined with the nearly one-third containing potentially harmful information risks undermining potential benefits of an e-Health approach to sexual health and well-being. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  11. Assessment of readability, quality and popularity of online information on ureteral stents.

    Science.gov (United States)

    Mozafarpour, Sarah; Norris, Briony; Borin, James; Eisner, Brian H

    2018-02-12

    To evaluate the quality and readability of online information on ureteral stents. Google.com was queried using the search terms "ureteric stent", "ureteral stent", "double J stent" and, "Kidney stent" derived from Google AdWords. Website popularity was determined using Google Rank and the Alexa tool. Website quality assessment was performed using the following criteria: Journal of the American Medical Association (JAMA) benchmarks, Health on the Net (HON) criteria, and a customized DISCERN questionnaire. The customized DISCERN questionnaire was developed by combining the short validated DISCERN questionnaire with additional stent-specific items including definition, placement, complications, limitations, removal and "when to seek help". Scores related to stent items were considered as the "stent score" (SS). Readability was evaluated using five readability tests. Thirty-two websites were included. The mean customized DISCERN score and "stent score" were 27.1 ± 7.1 (maximum possible score = 59) and 14.6 ± 3.8 (maximum possible score = 24), respectively. A minority of websites adequately addressed "stent removal" and "when to seek medical attention". Only two websites (6.3%) had HON certification (drugs.com, radiologyinfo.org) and only one website (3.3%) met all JAMA criteria (bradyurology.blogspot.com). Readability level was higher than the American Medical Association recommendation of sixth-grade level for more than 75% of the websites. There was no correlation between Google rank, Alexa rank, and the quality scores (P > 0.05). Among the 32 most popular websites on the topic of ureteral stents, online information was highly variable. The readability of many of the websites was far higher than standard recommendations and the online information was questionable in many cases. These findings suggest a need for improved online resources in order to better educate patients about ureteral stents and also should inform physicians that popular websites may

  12. Kinesiology taping and the world wide web: a quality and content analysis of internet-based information.

    Science.gov (United States)

    Beutel, Bryan G; Cardone, Dennis A

    2014-10-01

    Due to limited regulation of websites, the quality and content of online health-related information has been questioned as prior studies have shown that websites often misrepresent orthopaedic conditions and treatments. Kinesio tape has gained popularity among athletes and the general public despite limited evidence supporting its efficacy. The primary objective of this study was to assess the quality and content of Internet-based information on Kinesio taping. An Internet search using the terms "Kinesio tape" and "kinesiology tape" was performed using the Google search engine. Websites returned within the first two pages of results, as well as hyperlinks embedded within these sites, were included in the study. These sites were subsequently classified by type. The quality of the website was determined by the Health On the Net (HON) score, an objective metric based upon recommendations from the United Nations for the ethical representation of health information. A content analysis was performed by noting specific misleading versus balanced features in each website. A total of 31 unique websites were identified. The majority of the websites (71%) were commercial. Out of a total possible 16 points, the mean HON score among the websites was 8.9 points (SD 2.2 points). The number of misleading features was significantly higher than the balanced features (p < 0.001). Fifty-eight percent of sites used anecdotal testimonials to promote the product. Only small percentages of websites discussed complications, alternatives, or provided accurate medical outcomes. Overall, commercial sites had a greater number of misleading features compared to non-commercial sites (p = 0.01). Websites discussing Kinesio tape are predominantly of poor quality and present misleading, imbalanced information. It is of ever-increasing importance that healthcare providers work to ensure that reliable, balanced, and accurate information be available to Internet users. IV.

  13. Reading level of privacy policies on Internet health Web sites.

    Science.gov (United States)

    Graber, Mark A; D'Alessandro, Donna M; Johnson-West, Jill

    2002-07-01

    Most individuals would like to maintain the privacy of their medical information on the World Wide Web (WWW). In response, commercial interests and other sites post privacy policies that are designed to inform users of how their information will be used. However, it is not known if these statements are comprehensible to most WWW users. The purpose of this study was to determine the reading level of privacy statements on Internet health Web sites and to determine whether these statements can inform users of their rights. This was a descriptive study. Eighty Internet health sites were examined and the readability of their privacy policies was determined. The selected sample included the top 25 Internet health sites as well as other sites that a user might encounter while researching a common problem such as high blood pressure. Sixty percent of the sites were commercial (.com), 17.5% were organizations (.org), 8.8% were from the United Kingdom (.uk), 3.8% were United States governmental (.gov), and 2.5% were educational (.edu). The readability level of the privacy policies was calculated using the Flesch, the Fry, and the SMOG readability levels. Of the 80 Internet health Web sites studied, 30% (including 23% of the commercial Web sites) had no privacy policy posted. The average readability level of the remaining sites required 2 years of college level education to comprehend, and no Web site had a privacy policy that was comprehensible by most English-speaking individuals in the United States. The privacy policies of health Web sites are not easily understood by most individuals in the United States and do not serve to inform users of their rights. Possible remedies include rewriting policies to make them comprehensible and protecting online health information by using legal statutes or standardized insignias indicating compliance with a set of privacy standards (eg, "Health on the Net" [HON] http://www.hon.ch).

  14. Estimating P-coverage of biosynthetic pathways in DNA libraries and screening by genetic selection: biotin biosynthesis in the marine microorganism Chromohalobacter.

    Science.gov (United States)

    Kim, Eun Jin; Angell, Scott; Janes, Jeff; Watanabe, Coran M H

    2008-06-01

    Traditional approaches to natural product discovery involve cell-based screening of natural product extracts followed by compound isolation and characterization. Their importance notwithstanding, continued mining leads to depletion of natural resources and the reisolation of previously identified metabolites. Metagenomic strategies aimed at localizing the biosynthetic cluster genes and expressing them in surrogate hosts offers one possible alternative. A fundamental question that naturally arises when pursuing such a strategy is, how large must the genomic library be to effectively represent the genome of an organism(s) and the biosynthetic gene clusters they harbor? Such an issue is certainly augmented in the absence of expensive robotics to expedite colony picking and/or screening of clones. We have developed an algorism, named BPC (biosynthetic pathway coverage), supported by molecular simulations to deduce the number of BAC clones required to achieve proper coverage of the genome and their respective biosynthetic pathways. The strategy has been applied to the construction of a large-insert BAC library from a marine microorganism, Hon6 (isolated from Honokohau, Maui) thought to represent a new species. The genomic library is constructed with a BAC yeast shuttle vector pClasper lacZ paving the way for the culturing of libraries in both prokaryotic and eukaryotic hosts. Flow cytometric methods are utilized to estimate the genome size of the organism and BPC implemented to assess P-coverage or percent coverage. A genetic selection strategy is illustrated, applications of which could expedite screening efforts in the identification and localization of biosynthetic pathways from marine microbial consortia, offering a powerful complement to genome sequencing and degenerate probe strategies. Implementing this approach, we report on the biotin biosynthetic pathway from the marine microorganism Hon6.

  15. Web-Based Information on the Treatment of Tobacco Dependence for Oral Health Professionals: Analysis of English-Written Websites.

    Science.gov (United States)

    Diniz-Freitas, Márcio; Insua, Angel; Keat, Ross; Fricain, Jean Christophe; Catros, Sylvain; Monteiro, Luis; Silva, Luis; Lodi, Giovanni; Pispero, Alberto; Albuquerque, Rui

    2017-10-20

    Studies have been conducted on the content and quality of Web-based information for patients who are interested in smoking cessation advice and for health care practitioners regarding the content of e-learning programs about tobacco cessation. However, to the best of our knowledge, there is no such information about the quality of Web-based learning resources regarding smoking cessation dedicated to oral health professionals. The aim of this study was to identify and evaluate the quality of the content of webpages providing information about smoking cessation for oral health care professionals. Websites were identified using Google and Health on Net (HON) search engines using the terms: smoking cessation OR quit smoking OR stop smoking OR 3As OR 5As OR tobacco counselling AND dentistry OR dental clinic OR dentist OR dental hygienist OR oral health professionals. The first 100 consecutive results of the 2 search engines were considered for the study. Quality assessment was rated using the DISCERN questionnaire, the Journal of the American Medical Association (JAMA) benchmarks, and the HON seal. In addition, smoking cessation content on each site was assessed using an abbreviated version of the Smoke Treatment Scale (STS-C) and the Smoking Treatment Scale-Rating (STS-R). To assess legibility of the selected websites, the Flesch Reading Ease (FRES) and the Flesch-Kinkaid Reading Grade Level (FKRGL) were used. Websites were also classified into multimedia and nonmultimedia and friendly and nonfriendly usability. Of the first 200 sites selected (100 of Google and 100 of HON), only 11 met the inclusion criteria and mainly belonged to governmental institutions (n=8), with the others being prepared by Professional Associations (n=2) and nonprofit organizations (n=1). Only 3 were exclusively dedicated to smoking cessation. The average score obtained with the DISCERN was 3.0, and the average score in the FKRGL and FRES was 13.31 (standard deviation, SD 3.34) and 40.73 (SD 15

  16. 48 CFR 301.607-71 - FAC-P/PM levels and requirements.

    Science.gov (United States)

    2010-10-01

    ... Certification—Program and Project Managers—Information Technology Technical Competencies, in the P/PM Handbook for additional information. (b)(1) Competencies. An applicant can satisfy the competency requirements... programs; (iii) Demonstration of knowledge, skills, and abilities; or (iv) Any combination of these three...

  17. Framework for Analytic Cognition (FAC): A Guide for Doing All-Source Intelligence Analysis

    Science.gov (United States)

    2011-12-01

    example showed that people consistently preferred Coke over Pepsi when they could see the labels. When the labels were removed, Pepsi was the... marketing , business planning, and strategic planning, at national and corporate levels around the world. It includes a number of sub-methodologies...that five forces influence every market and industry.” The five forces are “Threat of New Entrants…Power of Suppliers…Power of Buyers…Availability of

  18. Comparison of the activities of wild type and mutant enhancing fac ...

    Indian Academy of Sciences (India)

    Unknown

    Laboratory of Genetic Engineering, Cancer Research Institute, Tata Memorial Centre, Parel, Mumbai 400 012, ... neth cells of the small intestine as well as to the hair fol- ... The active site of the enzyme shows the .... stand overnight at – 20ºC.

  19. Pseudosymmetric fac-di-aqua-trichlorido[(di-methyl-phosphor-yl)methanaminium-κO]manganese(II).

    Science.gov (United States)

    Reiss, Guido J

    2013-05-01

    In the title compound, [Mn(C3H11NOP)Cl3(H2O)2], the Mn(II) metal center has a distorted o-cta-hedral geometry, coordinated by the three chloride ligands showing a facial arrangement. Two water mol-ecules and the O-coordinated dpmaH cation [dpmaH = (di-methyl-phosphor-yl)methanaminium] complete the coordination sphere. Each complex mol-ecule is connected to its neighbours by O-H⋯Cl and N-H⋯Cl hydrogen bonds. Two of the chloride ligands and the two water ligands form a hydrogen-bonded polymeric sheet in the ab plane. Furthermore, these planes are connected to adjacent planes by hydrogen bonds from the aminium function of cationic dpmaH ligand. A pseudo-mirror plane perpendicular to the b axis in the chiral space group P21 is observed together with inversion twinning [ratio = 0.864 (5):0.136 (5)].

  20. Detection and transmission of extracellular fac-tor producing Streptococcus suis serotype 2 strains in pigs

    NARCIS (Netherlands)

    Swildens, B.

    2009-01-01

    DETECTION AND TRANSMISSION OF EXTRACELLULAR FACTOR PRODUCING STREPTOCOCCUS SUIS SEROTYPE 2 STRAINS IN PIGS INTRODUCTION Streptococcus suis (S.suis) has been implicated in the etiology of many diseases among which meningitis in pigs. The virulent extracellular factor-positive strains of S.suis

  1. Improving the characterization of endothelial progenitor cell subsets by an optimized FACS protocol.

    Directory of Open Access Journals (Sweden)

    Karin Huizer

    Full Text Available The characterization of circulating endothelial progenitor cells (EPCs is fundamental to any study related to angiogenesis. Unfortunately, current literature lacks consistency in the definition of EPC subsets due to variations in isolation strategies and inconsistencies in the use of lineage markers. Here we address critical points in the identification of hematopoietic progenitor cells (HPCs, circulating endothelial cells (CECs, and culture-generated outgrowth endothelial cells (OECs from blood samples of healthy adults (AB and umbilical cord (UCB. Peripheral blood mononuclear cells (PBMCs were enriched using a Ficoll-based gradient followed by an optimized staining and gating strategy to enrich for the target cells. Sorted EPC populations were subjected to RT-PCR for tracing the expression of markers beyond the limits of cell surface-based immunophenotyping. Using CD34, CD133 and c-kit staining, combined with FSC and SSC, we succeeded in the accurate and reproducible identification of four HPC subgroups and found significant differences in the respective populations in AB vs. UCB. Co-expression analysis of endothelial markers on HPCs revealed a complex pattern characterized by various subpopulations. CECs were identified by using CD34, KDR, CD45, and additional endothelial markers, and were subdivided according to their apoptotic state and expression of c-kit. Comparison of UCB-CECs vs. AB-CECs revealed significant differences in CD34 and KDR levels. OECs were grown from PBMC-fractions We found that viable c-kit+ CECs are a candidate circulating precursor for CECs. RT-PCR to angiogenic factors and receptors revealed that all EPC subsets expressed angiogenesis-related molecules. Taken together, the improvements in immunophenotyping and gating strategies resulted in accurate identification and comparison of better defined cell populations in a single procedure.

  2. Facéties de la visagéïté.

    Directory of Open Access Journals (Sweden)

    Eduardo Camacho-Hübner

    2005-07-01

    Full Text Available Trois fils de fer dorés à la feuille d’or, perchés sur un poteau d’une dizaine de mètres de haut et tordus de manière à tromper l’ennui du passant attentif. La sculpture qui trône sur le côté nord de la Place du Rhône à Genève est une belle métaphore du débat français autour du référendum sur la constitution européenne. L’espace de la place représente à la fois la frontière floue entre l’acceptation et le rejet du Traité constitutionnel, et l’espace public ...

  3. O exercício do poder e a exclusão de indivíduos e de línguas da sociedade brasileira = Power politics and the exclusion of individuals and languages in Brazilian society

    Directory of Open Access Journals (Sweden)

    Renata Adriana de Souza

    2008-07-01

    Full Text Available Neste artigo abordaremos o modo como a implantação do bilinguismo, emmeados da década de 1970, consistiu em um mecanismo de poder que buscou domesticar a diferença linguística existente entre os povos indígenas do Brasil, por meio da implantação do português. Os pressupostos teóricos da Análise de Discurso (AD contribuíram paraverificarmos as condições de produção e o contexto sócio-histórico em que o ensino bilíngue foi implantado. Junto a essa teoria temos, também, os estudos de Foucault (2005 que problematizam o modo como o poder se espalha por todas as instâncias da sociedade, excluindo determinados grupos e os aspectos culturais relacionados a eles, e os de Honório (2006 que discutem a implantação do bilinguismo no Brasil. É no cruzamento entre essas teorias que buscamos refletir sobre a problemática referente à implantação do bilinguismo,trazendo, como exemplo ilustrativo, um levantamento da situação linguística de um grupo de Kaingang.Current essay analyzes the introduction of bilingualism in the mid-1970s as a strategy of power politics to domesticate linguistic differences among the indigenous peoples of Brazil. Discourse Analysis’s theoretical presuppositions verify the production conditions and the social and historical context in which bilingual learning was introduced and established. Coupled to the above, Foucault’s studies problematize the manner power spreads throughout society with the exclusion of certain groups and culturalaspects linked to them. Further, Honório (2006 investigates the introduction of bilingualism in Brazil. Issues on the problem of the introduction of bilingualism have been produced through the intercrossing of the above-mentioned theories with special referenceto the linguistic situation of a Kaingang indigenous community.

  4. Britain's nuclear energy policy

    International Nuclear Information System (INIS)

    Duncan, Colin D.

    2000-01-01

    Full text: In the mid 1980s the Labour Party's position and clear intention was to phase out nuclear generated power in the UK. BNFL's reprocessing business was singled out for particular criticism. Many argued that this sounded the death knell for an industry with a legacy of negative public opinion and no commercial future. How against this background then was the Rt. Hon Tony Blair able, on 9 June 1999, to state that 'If we were to question the continued operation of Thorp, I think that would not be right. Thorp is an operation with orders now valued at some 12 billion pounds, it provides 6000 skilled jobs, it indirectly supports many more... I do not support the case of those who would like us to abandon Thorp?' Furthermore, in June 1999 the Royal Society stated that, 'it is vital to keep the nuclear option open' and in October of the same year the House of Commons Trade Industry Select Committee went further and advised, 'a formal presumption be made now for the purposes of long-term planning that new nuclear plant may be required in the course of the next two decades'. On 13 July 1999, the Secretary of State for Trade and Industry, Rt. Hon Stephen Byers, announced a possible sale of up to 49% of BNFL by a Public Private Partnership. Dare we view this as the genesis of a nuclear renaissance for the United Kingdom? This clear change in political attitude towards the nuclear option has come about as a result of a concerted public and government relations effort over the past ten years. That said, many barriers remain if we are to meet the challenge of delivering new nuclear build in the UK. Public opinion may allow new build but only if the industry demonstrates a track record of safety and environmental stewardship. There will always be the 'not in my back yard' argument so we must be a good neighbour and, most importantly of all, a long-term solution must be found for the disposal of nuclear waste. If the stage is set for the nuclear renaissance, the industry

  5. Geological mapping of the Kuiper quadrangle (H06) of Mercury

    Science.gov (United States)

    Giacomini, Lorenza; Massironi, Matteo; Galluzzi, Valentina

    2017-04-01

    Kuiper quadrangle (H06) is located at the equatorial zone of Mercury and encompasses the area between longitudes 288°E - 360°E and latitudes 22.5°N - 22.5°S. The quadrangle was previously mapped for its most part by De Hon et al. (1981) that, using Mariner10 data, produced a final 1:5M scale map of the area. In this work we present the preliminary results of a more detailed geological map (1:3M scale) of the Kuiper quadrangle that we compiled using the higher resolution of MESSENGER data. The main basemap used for the mapping is the MDIS (Mercury Dual Imaging System) 166 m/pixel BDR (map-projected Basemap reduced Data Record) mosaic. Additional datasets were also taken into account, such as DLR stereo-DEM of the region (Preusker et al., 2016), global mosaics with high-incidence illumination from the east and west (Chabot et al., 2016) and MDIS global color mosaic (Denevi et al., 2016). The preliminary geological map shows that the western part of the quadrangle is characterized by a prevalence of crater materials (i.e. crater floor, crater ejecta) which were distinguished into three classes on the basis of their degradation degree (Galluzzi et al., 2016). Different plain units were also identified and classified as: (i) intercrater plains, represented by densely cratered terrains, (ii) intermediate plains, which are terrains with a moderate density of superposed craters, and (iii) smooth plains, which are poorly cratered volcanic deposits emplaced mainly on the larger crater floors. Finally, several structures were mapped all over the quadrangle. Most of these features are represented by thrusts, some of which appear to form systematic alignments. In particular, two main thrust systems have been identified: i) the "Thakur" system, a 1500 km-long system including several scarps with a NNE-SSW orientation, located at the edge between the Kuiper and Beethoven (H07) quadrangles; ii) the "Santa Maria" system, located at the centre of the quadrangle. It is a 1700 km

  6. A humanist's legacy in medical informatics: visions and accomplishments of Professor Jean-Raoul Scherrer.

    Science.gov (United States)

    Geissbühler, A; Lovis, C; Spahni, S; Appel, R D; Ratib, O; Boyer, C; Hochstrasser, D F; Baud, R

    2002-01-01

    To report about the work of Prof. Jean-Raoul Scherrer, and show how his humanist vision, his medical skills and his scientific background have enabled and shaped the development of medical informatics over the last 30 years. Starting with the mainframe-based patient-centered hospital information system DIOGENE in the 70s, Prof. Scherrer developed, implemented and evolved innovative concepts of man-machine interfaces, distributed and federated environments, leading the way with information systems that obstinately focused on the support of care providers and patients. Through a rigorous design of terminologies and ontologies, the DIOGENE data would then serve as a basis for the development of clinical research, data mining, and lead to innovative natural language processing techniques. In parallel, Prof. Scherrer supported the development of medical image management, ranging from a distributed picture archiving and communication systems (PACS) to molecular imaging of protein electrophoreses. Recognizing the need for improving the quality and trustworthiness of medical information on the Web, Prof. Scherrer created the Health-On-the-Net (HON) foundation. These achievements, made possible thanks to his visionary mind, deep humanism, creativity, generosity and determination, have made of Prof. Scherrer a true pioneer and leader of the human-centered, patient-oriented application of information technology for improving healthcare.

  7. Radiopharmaceuticals of DTPA, DMSA and EDTA labeled with holmium-166

    International Nuclear Information System (INIS)

    Rahman, M.; Matsouka, H.; Takami, S.; Terunuma, K.

    2001-01-01

    DTPA, DMSA and EDTA were labelled with 166 Ho of low specific activity, 250-275mCi/mg of Ho, produced from holmium oxide by the 165 Ho(n, g) 166 Ho reaction at a neutron flux of about 10 14 n.cm -2 .s -1 . Three pH ranges were selected in the study, viz. 2-3, 3-3.5 and 5-6. The labelling reactions were studied as chloride and nitrate solutions in aqueous and saline media at 30 min and 20-24 h of reaction. DTPA was labelled over 99, DMSA at about 90 and EDTA at 100.0% with 166 Ho. The complexes were found stable at all times of investigation. A beta chromatogram scanner was used to study by TLC the labelling reactions of DTPA and DMSA with the nuclide and by PC those of EDTA. A biodistribution study in three rats injected intravenous with a saline solution of 166 HoCl 3 [DTPA] at pH5.1 showed an initial uptake in blood, kidney and lung after 30 minutes. After four hours the complex was found to have cleared from blood and lung, and localized 100% in kidney. It was stable in vivo in the kidney after 24 hours. The g spectrum analysis did not show the formation of any impurity except the four characteristic g energies of 166 Ho. (author)

  8. Direct to consumer advertising via the Internet, a study of hip resurfacing.

    Science.gov (United States)

    Ogunwale, B; Clarke, J; Young, D; Mohammed, A; Patil, S; Meek, R M D

    2009-02-01

    With increased use of the internet for health information and direct to consumer advertising from medical companies, there is concern about the quality of information available to patients. The aim of this study was to examine the quality of health information on the internet for hip resurfacing. An assessment tool was designed to measure quality of information. Websites were measured on credibility of source; usability; currentness of the information; content relevance; content accuracy/completeness and disclosure/bias. Each website assessed was given a total score, based on number of scores achieved from the above categories websites were further analysed on author, geographical origin and possession of an independent credibility check. There was positive correlation between the overall score for the website and the score of each website in each assessment category. Websites by implant companies, doctors and hospitals scored poorly. Websites with an independent credibility check such as Health on the Net (HoN) scored twice the total scores of websites without. Like other internet health websites, the quality of information on hip resurfacing websites is variable. This study highlights methods by which to assess the quality of health information on the internet and advocates that patients should look for a statement of an "independent credibility check" when searching for information on hip resurfacing.

  9. THE NIGERIA DATA PROTECTION BILL: APPRAISAL, ISSUES, AND CHALLENGES

    Directory of Open Access Journals (Sweden)

    Abubakar Sanni Aliyu

    2016-02-01

    Full Text Available Nigeria has absolutely no privacy and personal information laws. This lacuna is even more material in an internet world where information published on the web is open to a global audience. It is in this regard that the Data Protection Bill was sponsored by Hon. Yakubu Dogara, member of the Federal House of Representatives, representing Bogoro/Dass/Tafawa Balewa Bauchi State, Nigeria. This paper has two key aims, firstly to find out the major issues address by the proposed Data Protection Bill 2010, secondly, to determine the significance and the challenges of the Bill to Nigeria environment. The study utilized secondary source of data from the Data Protection Bill, 2010 and other documentary sources for analysis. The study finds out that the Bill protect parties in regard to publication of market survey details and information, ensure that unauthorised processing of personal information is reduce, and use of personal data and information without the prior consent of the data is subjected to scrutiny. The paper recommends that the Federal Government of Nigeria and the policy makers should hasten the process of passing the Bill into law in order to strengthen the activities of ecommerce in Nigeria through the following benefits: Improved customer relations; Improved ability to market lawfully; Improved data quality; Improved data security among others.

  10. Complete active space second order perturbation theory (CASPT2) study of N({sup 2}D) + H{sub 2}O reaction paths on D{sub 1} and D{sub 0} potential energy surfaces: Direct and roaming pathways

    Energy Technology Data Exchange (ETDEWEB)

    Isegawa, Miho; Liu, Fengyi [Fukui Institute for Fundamental Chemistry, Kyoto University, 34-4 Takano Nishihiraki-cho, Kyoto 606-8103 (Japan); Maeda, Satoshi [Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo 060-0810 (Japan); Morokuma, Keiji, E-mail: morokuma@fukui.kyoto-u.ac.jp [Fukui Institute for Fundamental Chemistry, Kyoto University, 34-4 Takano Nishihiraki-cho, Kyoto 606-8103 (Japan); Cherry L. Emerson Center for Scientific Computation and Department of Chemistry, Emory University, Atlanta, Georgia 30322 (United States)

    2014-10-21

    We report reaction paths starting from N({sup 2}D) + H{sub 2}O for doublet spin states, D{sub 0} and D{sub 1}. The potential energy surfaces are explored in an automated fashion using the global reaction route mapping strategy. The critical points and reaction paths have been fully optimized at the complete active space second order perturbation theory level taking all valence electrons in the active space. In addition to direct dissociation pathways that would be dominant, three roaming processes, two roaming dissociation, and one roaming isomerization: (1) H{sub 2}ON → H–O(H)N → H–HON → NO({sup 2}Π) + H{sub 2}, (2) cis-HNOH → HNO–H → H–HNO → NO + H{sub 2}, (3) H{sub 2}NO → H–HNO → HNO–H → trans-HNOH, are confirmed on the D{sub 0} surface.

  11. Early nursing career experience for 1994-2000 graduates from the University of Nottingham.

    Science.gov (United States)

    Park, Jennifer R; Chapple, Mary; Wharrad, Heather; Bradley, Sue

    2007-05-01

    This paper reports the views of nurses graduating from the University of Nottingham School of Nursing, UK, 1994-2000, Bachelor of Nursing (Hons) course, concerning career aspirations, progress and reflections on their qualification. Alongside academic knowledge and practical skills, this four-year Bachelor of Nursing course aimed to develop students' critical thinking and research skills. The degree's effect on nurses' career trajectories is unknown. Self-completion questionnaires employing open and closed questions were sent to graduates 9 months after graduation and at intervals over the next 6 years. Most respondents were confident and motivated in their nursing careers. Promotion, increased responsibility, further study, specialization and qualifications were career priorities. Recent qualifiers also focused on changing jobs, travel and working overseas. The graduates' experience has salience for nurse managers, especially when matching graduates against post outlines within the knowledge and skills framework, considering staff skill mix, and advising graduates about their development and assisting them to find satisfaction in their nursing careers.

  12. Association of surgeons in training 40th anniversary conference: Liverpool #ASiT2016.

    Science.gov (United States)

    Harries, Rhiannon L; Williams, Adam P; McElnay, Philip J; Gokani, Vimal J

    2016-11-01

    The Association of Surgeons in Training (ASiT) is a professional body and registered charity working to promote excellence in surgical training for the benefit of junior doctors and patient alike. ASiT is independent of the National Health Service (NHS), Surgical Royal Colleges and specialty associations, and represents trainees in all ten surgical specialities. We were delighted to be celebrating our 40th Anniversary Conference in the fantastic city of Liverpool with over 700 delegates in attendance and in the company of many ASiT Past Presidents. The conference programme focused on how to overcome threats to training in light of the recent turbulent events associated with the junior doctor contract dispute with inspiring talks from Professor Sir Bruce Keogh, NHS Medical Director and Rt Hon Heidi Alexander MP, Shadow Health Secretary. The other central topic to the conference was 'celebrating excellence in surgical training' and we were thankful to many other high profile speakers who attended to help in this celebration. In addition, over £4000 was distributed between more than 30 prizes and was awarded by the incoming President, Mr Adam Williams, to delegates who presented the highest scoring academic work from over 1200 submitted abstracts. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  13. ACUTE EFFECTS OF DIFFERENT STATIC STRETCHING PROTOCOLS ON PEAK TORQUE, CONVENTIONAL AND FUNCTIONAL HAMSTRINGS-TO-QUADRICEPS RATIOS IN ACTIVE WOMEN

    Directory of Open Access Journals (Sweden)

    Ghada M. ALQaslah

    2016-10-01

    Full Text Available Background: This study might have been directed to some degree because of clashing results in the past studies regarding the impacts for different SS protocols on muscle strength and possibility for injury. The objective of the study was to investigate the acute effects of different static stretching (SS durations (20, 30, and 60s on isokinetic concentric quadriceps (Q and hamstrings (H peak torque (PT, eccentric H PT and conventional and functional H:Q ratios under different stretching conditions and angular velocities (60°and180°/s in active women. Methods: Isokinetic tests were performed on 108 active women. A HUMAC system was used to measure unilateral concentric Q and H PT, and eccentric H PT at 60 and 180º/s at baseline and after a bout of H-only, Q-only, and combined H and Q muscles SS. The data were statistically treated using five separate three-way (time x conditions x velocity ANOVA. Results: There were no significant differences among groups at baseline (P > 0.05. Significant reductions of all outcome measures have been shown to occur after 30 and 60s of SS (P 0.05. Conclusion: Short-lasting stretching can be done before exercises that require strength. However, since 30s or 60s stretching protocols adversely affect the muscle strength, performance and lower H:Q ratios they are not recommended prior to activities demanding the production of high forces.

  14. Acute gastroenteritis: from guidelines to real life

    Directory of Open Access Journals (Sweden)

    Chung M Chow

    2010-07-01

    Full Text Available Chung M Chow1, Alexander KC Leung2, Kam L Hon11Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, PR China; 2Department of Pediatrics, The University of Calgary, Calgary, Alberta, CanadaAbstract: Acute gastroenteritis is a very common disease. It causes significant mortality in developing countries and significant economic burden to developed countries. Viruses are ­responsible for approximately 70% of episodes of acute gastroenteritis in children and rotavirus is one of the best studied of these viruses. Oral rehydration therapy is as effective as i­ntravenous therapy in treating mild to moderate dehydration in acute gastroenteritis and is strongly r­ecommended as the first line therapy. However, the oral rehydration solution is described as an underused simple solution. Vomiting is one of the main reasons to explain the underuse of oral rehydration therapy. Antiemetics are not routinely recommended in treating acute gastroenteritis, though they are still commonly prescribed. Ondansetron is one of the best studied antiemetics and its role in enhancing the compliance of oral rehydration therapy and decreasing the rate of hospitalization has been proved recently. The guidelines regarding the recommendation on antiemetics have been changed according to the evidence of these recent studies.Keywords: gastroenteritis, vomiting, antiemetic, ondansetron, rotavirus, oral rehydration therapy, intravenous therapy, guideline

  15. Head and neck cancer information on the internet: type, accuracy and content.

    LENUS (Irish Health Repository)

    Ni Riordain, Richeal

    2009-08-01

    This study aimed to determine the type, accuracy and content of information available on the internet regarding head and neck cancer. The search engine Google was used to generate a list of the top 100 websites about head and neck cancer. The websites were evaluated using the DISCERN instrument and the JAMA benchmarks and whether the site displayed the Health on the Net seal was also recorded. The search yielded 1,650,000 sites on the Google website. Of the top 100 sites, a total of 33 sites were suitable for analysis due to duplicate links, non-functioning links and irrelevant website. 45% achieved all four JAMA benchmarks and 18% achieved only 1 benchmark. No website receiving the maximum mark on the overall score and four websites received the lowest overall score regarding the DISCERN instrument. The question with the poorest response score was \\'Does it describe how the treatment choices affect overall quality of life?\\' 39% of the websites displayed the Health on the Net (HON) seal. A wide variety of types of information are available on the internet regarding head and neck cancer with variable accuracy levels based on both Journal of the American Medical Association (JAMA) benchmarks and DISCERN. The onus lies with the practitioner to guide the patient regarding scientific reliability of information and to direct the patient in filtering the information sourced. The inclusion of quality of life related information is currently lacking and should be addressed to ensure a more comprehensive understanding for patients of treatment options.

  16. Tensor decomposition in electronic structure calculations on 3D Cartesian grids

    International Nuclear Information System (INIS)

    Khoromskij, B.N.; Khoromskaia, V.; Chinnamsetty, S.R.; Flad, H.-J.

    2009-01-01

    In this paper, we investigate a novel approach based on the combination of Tucker-type and canonical tensor decomposition techniques for the efficient numerical approximation of functions and operators in electronic structure calculations. In particular, we study applicability of tensor approximations for the numerical solution of Hartree-Fock and Kohn-Sham equations on 3D Cartesian grids. We show that the orthogonal Tucker-type tensor approximation of electron density and Hartree potential of simple molecules leads to low tensor rank representations. This enables an efficient tensor-product convolution scheme for the computation of the Hartree potential using a collocation-type approximation via piecewise constant basis functions on a uniform nxnxn grid. Combined with the Richardson extrapolation, our approach exhibits O(h 3 ) convergence in the grid-size h=O(n -1 ). Moreover, this requires O(3rn+r 3 ) storage, where r denotes the Tucker rank of the electron density with r=O(logn), almost uniformly in n. For example, calculations of the Coulomb matrix and the Hartree-Fock energy for the CH 4 molecule, with a pseudopotential on the C atom, achieved accuracies of the order of 10 -6 hartree with a grid-size n of several hundreds. Since the tensor-product convolution in 3D is performed via 1D convolution transforms, our scheme markedly outperforms the 3D-FFT in both the computing time and storage requirements.

  17. From Spintronics to CFD/ContractForDifferences

    Science.gov (United States)

    Maksoed, W. H.

    2015-11-01

    Involve the CFD/Computational Fluid Dynamics & HCCI/Homogeneous Charge Compression Ignition - Marcine Frackowiak, dissertation, 2009, for CFD/Contract For Differences accompanied by ``One Man's Crusade to Exonerate Hydrogen for Hindenburg Disaster'' of Addison BAIN, APS News, v. 9, n.7 (July 2000) concludes ``ignition of the blaze'' are responsible to those May, 1937 Accidents. Spintronics their selves include active control & manipulation of spin degree of freedom ever denotes: the nano-obelisk of scanning electron microscopy of galliumnitride/GaN nanostructures-Yong-Hon Cho et al.:``Novel Photonic Device using core-shell nanostructures'', SPIE-newsroom,10.1117/2.1201503.005864. Herewith commercial activated carbon/C can be imaged directly using abberation-corrected transmission electron microscopy[PJF Harris et al.: ``Imaging the Atomic Structures of activated C'', J. Phys. Condens. Matt, 20 (2008) in fig b & c- images networks of hexagonal rings can be clearly be seen depicts equal etchings of 340 px Akhenaten, Nefertiti & their childrens. Incredible acknowledgments to Minister of Education & Culture RI 1998-1999 HE. Mr. Prof. Ir. WIRANTO ARISMUNANDAR, MSME.

  18. Quality of Web-based information on obsessive compulsive disorder.

    Science.gov (United States)

    Klila, Hedi; Chatton, Anne; Zermatten, Ariane; Khan, Riaz; Preisig, Martin; Khazaal, Yasser

    2013-01-01

    The Internet is increasingly used as a source of information for mental health issues. The burden of obsessive compulsive disorder (OCD) may lead persons with diagnosed or undiagnosed OCD, and their relatives, to search for good quality information on the Web. This study aimed to evaluate the quality of Web-based information on English-language sites dealing with OCD and to compare the quality of websites found through a general and a medically specialized search engine. Keywords related to OCD were entered into Google and OmniMedicalSearch. Websites were assessed on the basis of accountability, interactivity, readability, and content quality. The "Health on the Net" (HON) quality label and the Brief DISCERN scale score were used as possible content quality indicators. Of the 235 links identified, 53 websites were analyzed. The content quality of the OCD websites examined was relatively good. The use of a specialized search engine did not offer an advantage in finding websites with better content quality. A score ≥16 on the Brief DISCERN scale is associated with better content quality. This study shows the acceptability of the content quality of OCD websites. There is no advantage in searching for information with a specialized search engine rather than a general one. The Internet offers a number of high quality OCD websites. It remains critical, however, to have a provider-patient talk about the information found on the Web.

  19. Quality of web-based information on pathological gambling.

    Science.gov (United States)

    Khazaal, Yasser; Chatton, Anne; Cochand, Sophie; Jermann, Françoise; Osiek, Christian; Bondolfi, Guido; Zullino, Daniele

    2008-09-01

    The present study aims to evaluate the quality of web-based information on gambling and to investigate potential content quality indicators. The following key words: gambling, pathological gambling, excessive gambling, gambling problem and gambling addiction were entered into two popular search engines: Google and Yahoo. Websites were assessed with a standardized proforma designed to rate sites on the basis of "accountability", "presentation", "interactivity", "readability" and "content quality". "Health on the Net" (HON) quality label, and DISCERN scale scores aiding people without content expertise to assess quality of written health publication were used to verify their efficiency as quality indicators. Of the 200 links identified, 75 websites were included. The results of the study indicate low scores on each of the measures. A composite global score appeared as a good content quality indicator. While gambling-related education websites for patients are common, their global quality is poor. There is a need for useful evidence-based information about gambling on the web. As the phenomenon has greatly increased, it could be relevant for Internet sites to improve their content by using global score as a quality indicator.

  20. Astronomical Books and Charts in the Book of Bibliographie Coreenne

    Directory of Open Access Journals (Sweden)

    Ki-Won Lee

    2008-06-01

    Full Text Available We investigate astronomical materials listed in the book of Bibliographie Coreenne written by Maurice Courant. He classified ancient Korean books into nine Divisions (部 and thirty six Classes (類, and published them as three volumes (ranging from 1894 to 1896 and one supplement (in 1901. In total, 3,821 books including astronomical ones are listed together with information on physical size, possessional place, bibliographical note, and so forth. Although this book is an essential one in the field of Korea bibliography and contains many astronomical materials such as Cheon-Mun-Ryu-Cho 天文類抄, Si-Heon-Seo 時憲書, and Cheon-Sang-Yeol-Cha-Bun-Ya-Ji-Do 天象列次分野之圖, it has not been well known to the public nor to astronomical society. Of 3,821 catalogues, we found that about 50 Items (種 are related to astronomy or astrology, and verified that most of them are located in the Kyujanggak Royal Library 奎章閣. We also found an unknown astronomical chart, Hon-Cheon-Chong-Seong-Yeol-Cha-Bun-Ya-Ji-Do 渾天總星列次分野之圖. Because those astronomical materials are not well known to international astronomical community and there have been few studies on the materials in Korea, we here introduce and review them, particularly with the astronomical viewpoint.

  1. Astronomical Books and Charts in the Book of Bibliographie Coreenne

    Science.gov (United States)

    Lee, Ki-Won; Yang, Hong-Jin; Park, Myeong-Gu

    2008-06-01

    We investigate astronomical materials listed in the book of Bibliographie Coréenne written by Maurice Courant. He classified ancient Korean books into nine Divisions (?) and thirty six Classes (?), and published them as three volumes (ranging from 1894 to 1896) and one supplement (in 1901). In total, 3,821 books including astronomical ones are listed together with information on physical size, possessional place, bibliographical note, and so forth. Although this book is an essential one in the field of Korea bibliography and contains many astronomical materials such as Cheon-Mun-Ryu-Cho ????, Si-Heon-Seo ??????, and Cheon-Sang-Yeol-Cha-Bun-Ya-Ji-Do ????????, it has not been well known to the public nor to astronomical society. Of 3,821 catalogues, we found that about 50 Items (?) are related to astronomy or astrology, and verified that most ! of them are located in the Kyujanggak Royal Library ???. We also found an unknown astronomical chart, Hon-Cheon-Chong-Seong-Yeol-Cha-Bun-Ya-Ji-Do ??????????. Because those astronomical materials are not well known to international astronomical community and there have been few studies on the materials in Korea, we here introduce and review them, particularly with the astronomical viewpoint.

  2. Improving the transparency of health information found on the internet through the honcode: a comparative study.

    Science.gov (United States)

    Laversin, Sabine; Baujard, Vincent; Gaudinat, Arnaud; Simonet, Maria-Ana; Boyer, Célia

    2011-01-01

    This study aims to show that health websites not asking for HONcode certification (Control sample websites A) do not respect elementary ethical standards such as the HONcode. The HONcode quality and ethical standards and the certification process have been developed by the Health on the Net Foundation to improve the transparency of the health and medical information found on the Internet. We compared the compliance with the 8 HONcode principles, and respectively the respect of principles 1 (authority), 4 (assignment), 5 (justification) and 8 (honesty in advertising and editorial policy) by certified websites (A) and by health websites which have not requested the certification (B). The assessment of the HONcode compliance was performed by HON evaluators by the same standards for all type of sites. Results shows that 0.6% of health websites not asking for HONcode certification does respect the eight HONcode ethical standards vs. 89% of certified websites. Regarding the principles 1, 4, 5 and 8, 1.2% of B respect these principles vs. 92% for A. The certification process led health websites to respect the ethical and quality standards such as the HONcode, and disclosing the production process of the health website.

  3. Quality and readability of English-language internet information for aphasia.

    Science.gov (United States)

    Azios, Jamie H; Bellon-Harn, Monica; Dockens, Ashley L; Manchaiah, Vinaya

    2017-08-14

    Little is known about the quality and readability of treatment information in specific neurogenic disorders, such as aphasia. The purpose of this study was to assess quality and readability of English-language Internet information available for aphasia treatment. Forty-three aphasia treatment websites were aggregated using five different country-specific search engines. Websites were then analysed using quality and readability assessments. Statistical calculations were employed to examine website ratings, differences between website origin and quality and readability scores, and correlations between readability instruments. Websites exhibited low quality with few websites obtaining Health On the Net (HON) certification or clear, thorough information as measured by the DISCERN. Regardless of website origin, readability scores were also poor. Approximate educational levels required to comprehend information on aphasia treatment websites ranged from 13 to 16 years of education. Significant differences were found between website origin and readability measures with higher levels of education required to understand information on websites of non-profit organisations. Current aphasia treatment websites were found to exhibit low levels of quality and readability, creating potential accessibility problems for people with aphasia and significant others. Websites including treatment information for aphasia must be improved in order to increase greater information accessibility.

  4. Influence of dissolved organic matter and manganese oxides on metal speciation in soil solution: A modelling approach.

    Science.gov (United States)

    Schneider, Arnaud R; Ponthieu, Marie; Cancès, Benjamin; Conreux, Alexandra; Morvan, Xavier; Gommeaux, Maxime; Marin, Béatrice; Benedetti, Marc F

    2016-06-01

    Trace element (TE) speciation modelling in soil solution is controlled by the assumptions made about the soil solution composition. To evaluate this influence, different assumptions using Visual MINTEQ were tested and compared to measurements of free TE concentrations. The soil column Donnan membrane technique (SC-DMT) was used to estimate the free TE (Cd, Cu, Ni, Pb and Zn) concentrations in six acidic soil solutions. A batch technique using DAX-8 resin was used to fractionate the dissolved organic matter (DOM) into four fractions: humic acids (HA), fulvic acids (FA), hydrophilic acids (Hy) and hydrophobic neutral organic matter (HON). To model TE speciation, particular attention was focused on the hydrous manganese oxides (HMO) and the Hy fraction, ligands not considered in most of the TE speciation modelling studies in soil solution. In this work, the model predictions of free ion activities agree with the experimental results. The knowledge of the FA fraction seems to be very useful, especially in the case of high DOM content, for more accurately representing experimental data. Finally, the role of the manganese oxides and of the Hy fraction on TE speciation was identified and, depending on the physicochemical conditions of the soil solution, should be considered in future studies. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. A cross-sectional content analysis of Android applications for asthma.

    Science.gov (United States)

    Househ, Mowafa; Hossain, Nassif; Jamal, Amr; Zakaria, Nasriah; Elmetwally, Ashraf; Alsalamah, Majid; Khalifa, Mohamed

    2017-06-01

    Providing patients opportunities for self-management and education about their disease, asthma applications designed for use on an Android operating system can have positive health outcomes across the range of demographics who use mHealth applications. This study provides a content analysis of freely available Google Android Platform Mobile Applications for Asthma. A list of applications was collected on 26 October 2014, using the search feature of the Google Play Android platform and using the words and phrases "Asthma," "Lung Function" and "Peak Flow." Each application was coded for its approach to asthma self-management, based on categories adapted by Huckvale et al., which are based on the Global Initiative for Asthma and the National Asthma Education and Prevention Program. The characteristics of the 15 asthma applications are described. Most of the asthma applications' primary function focused on patient self-monitoring and self-assessment. Using the HON Code, we found low health information quality across all asthma applications. Android asthma applications can have positive outcomes in helping patients as they provide opportunities for self-management and education about their disease. Future research should continue to monitor and evaluate the development and use of mHealth Asthma Applications. Based on these findings, and their indication of a gap in existing research, subsequent studies can continue to evaluate the development and use of mHealth Asthma Applications with increasing methodological consistency to improve the quality of in-app health information.

  6. What’s in the pipeline? Drugs in development for autism spectrum disorder

    Directory of Open Access Journals (Sweden)

    Sung M

    2014-02-01

    Full Text Available Min Sung,1 Chee Hon Chin,1 Choon Guan Lim,1 Hwee Sen Alvin Liew,1 Chau Sian Lim,2 Espérance Kashala,1 Shih-Jen Weng1 1Department of Child and Adolescent Psychiatry, Institute of Mental Health, Singapore; 2Department of Psychological Medicine, Khoo Teck Puat Hospital, Singapore Abstract: Autism Spectrum Disorder (ASD is a complex neurodevelopmental disorder with both core symptoms and associated symptoms (eg, irritability, aggression, and comorbidities that affect both the individual and the family/systems around them. There have been recent advances in the understanding of the underlying pathophysiology of ASD pertaining to genetics, epigenetics, neurological, hormonal, and environmental factors that contribute to the difficulties found in individuals with ASD. With this improved understanding, there has been a shift in the application of psychopharmacology in ASD and its related disorders. A literature review was conducted to examine research published in the last 5 years between different classes of psychotropic medications and ASD. The broad scope of the existing literature for the use of conventional medications is summarized and novel medications are discussed. Keywords: pharmacology, treatment, autism, Asperger’s syndrome, medication

  7. ENN-ICS - quality assurance and online evaluation of a multilingual learning management system for sleep medicine

    Directory of Open Access Journals (Sweden)

    Knobl, Brigitte

    2006-11-01

    Full Text Available With the development and implementation of a multilingual interactive communication system the e-health project ENN-ICS, funded by the European Union, aims at the improvement of health care in Europe. The field of application is sleep physiology and sleep medicine. ENN-ICS Centre offers direct access to medical information for multiple users, i.e. health authorities, health care professionals, patients and citizen. Using XML technologies the new web based network integrates advanced e-learning and e-publishing methods for the training of healthcare professionals. Editorial and distributive processes are supported by customized central editorial, content management and learning management systems (CMS, LMS. ENN-ICS e-health services are evaluated by selected user groups in North, Middle and Southern Europe using reliable and scientifically accepted validation instruments. The compliance with essential quality requirements and criteria is tested and verified by using adapted online questionnaires based on the DISCERN questionnaire for evaluating patient information, on the HON principles for evaluating health-related websites and on the GMDS catalogue of quality criteria for electronic publications in medicine. The system architecture and its exemplary applications can be used as a model for future e-health services dealing with neurological and other medical topics.

  8. Hydrogenation of aromatic compounds during gas oil hydrodewaxing. Part 1. Effect of ruthenium content and method of nickel catalyst preparation

    Energy Technology Data Exchange (ETDEWEB)

    Masalska, Aleksandra [Wroclaw University of Technology, Faculty of Chemistry, 7/9 Gdanska Street, 50-344 Wroclaw (Poland)

    2008-09-30

    Ni-based (8 wt.% NiO) dewaxing catalysts for the hydroconversion of the hydroraffinate of oil fraction (d{sub 20} {sub C} = 0.845 g/cm{sup 3}; cloud point (CP) -2 C; aromatics = 25.8 wt.%; S = 25 ppm) were modified with Ru. The effect of Ru content (0.6, 0.75 and 0.9 wt.% of RuO{sub 2}) and the methods of Ni catalyst preparation were examined. The catalysts were characterised by N{sub 2} sorption, TPR, ICP, XRD, SEM, XPS, H{sub 2} chemisorption. Activity was tested in a continuous-flow system at 6 MPa (LHSV, 2.5 h{sup -1}; H{sub 2}:CH, 350 N m{sup 3}/m{sup 3}). NiO and RuO{sub 2} were found to exert a synergic effect on catalytic activity. The rise in RuO{sub 2} content from 0.6 to 0.9 wt.% increased the HDA of HON from 23 to 65% at 240 C and was parallelled by a drop in CP (by about 15 C). The effect of Ru was found to depend on the method of Ni catalyst preparation. (author)

  9. Intrapartum FHR monitoring and neonatal CT brain scan

    International Nuclear Information System (INIS)

    Takahashi, Yoshiki; Ukita, Masahiko; Nakada, Eizo

    1982-01-01

    The effect of fetal distress on the neonatal brain was investigated by neonatal CT brain scan, FHR monitoring and mode of delivery. This study involved 11 cases of full term vertex delivery in which FHR was recorded by fetal direct ECG during the second stage labor. All infants weighed 2,500 g or more. FHR monitoring was evaluated by Hon's classification. Neonatal brain edema was evaluated by cranial CT histgraphic analysis (Nakada's method). 1) Subdural hemorrhage was noted in 6 of 7 infants delivered by vacuum extraction or fundal pressure (Kristeller's method). 2) Intracranial hemorrhage was demonstrated in all of 3 infants with 5-min. Apgar score 7 or less. 3) Two cases with prolonged bradycardia and no variability had intraventricular or intracerebral hemorrhage which resulted in severe central nervous system damage. 4) The degree of neonatal brain edema correlated with 5-min. Apgar score. 5) One case with prolonged bradycardia and no variability resulted in severe neonatal brain edema. Four cases with variable deceleration and increased variability resulted in mild neonatal brain edema. Two cases with late deceleration and decreased variability resulted in no neonatal brain edema. (author)

  10. Directional Darwinian Selection in proteins.

    Science.gov (United States)

    McClellan, David A

    2013-01-01

    Molecular evolution is a very active field of research, with several complementary approaches, including dN/dS, HON90, MM01, and others. Each has documented strengths and weaknesses, and no one approach provides a clear picture of how natural selection works at the molecular level. The purpose of this work is to present a simple new method that uses quantitative amino acid properties to identify and characterize directional selection in proteins. Inferred amino acid replacements are viewed through the prism of a single physicochemical property to determine the amount and direction of change caused by each replacement. This allows the calculation of the probability that the mean change in the single property associated with the amino acid replacements is equal to zero (H0: μ = 0; i.e., no net change) using a simple two-tailed t-test. Example data from calanoid and cyclopoid copepod cytochrome oxidase subunit I sequence pairs are presented to demonstrate how directional selection may be linked to major shifts in adaptive zones, and that convergent evolution at the whole organism level may be the result of convergent protein adaptations. Rather than replace previous methods, this new method further complements existing methods to provide a holistic glimpse of how natural selection shapes protein structure and function over evolutionary time.

  11. Student nurse perceptions of risk in relation to international placements: a phenomenological research study.

    Science.gov (United States)

    Morgan, Debra A

    2012-11-01

    International nursing electives have been identified as a positive learning experience for students. However, whilst there are risks associated with international student placements in general, there is a scarcity of research specifically relating to student nurse's experiences of risk. This study aimed to investigate UK undergraduate student nurse experiences of risk during an international placement. A phenomenological methodology was applied and semi-structured interviews were conducted with student nurses who had recently returned from an international clinical placement abroad. Ten, second year student nurses, studying on a pre-registration diploma/BSc (Hons) Nursing Studies/Registered Nurse programme from one UK University participated in the study. Findings from the study highlighted that students felt that three types of risk existed; physical risk, clinical-professional risk and socio-cultural risk. Perceptions of risk were influenced by sociological theory relating to the concept of 'the other' and students attempted to reduce risk by employing strategies to reduce 'Otherness'. They also applied psychological theory relating to heuristics such as 'safety in numbers.' It also emerged from the study that exposure to perceived risk enhanced learning as students reported that it encouraged personal and professional development in particular and so assisted students in their move toward self-actualisation. It is suggested, and intended, that findings from this study can be applied to the preparation of students to further enhance their safety and learning experience during international placements abroad. Copyright © 2011 Elsevier Ltd. All rights reserved.

  12. Konverze objektu dormitory na hostel a jeho nové řešení v Tomioka Silk Mill, Japonsko

    OpenAIRE

    Brezovský, Jindřich

    2012-01-01

    Diplomová práce s názvem „KONVERZE OBJEKTU DORMITORY NA HOSTEL A JEHO NOVÉ ŘEŠENÍ V TOMIOKA SILK MILL, JAPONSKO“ je zpracována dle platných předpisů ve formě architektonické studie. Předmětem této práce jsou dvě varianty konverze objektu pro ubytování dělnic (dormitory). Dílčím úkolem je řešení úpravy zeleně v atriu dormitory a návrh revitalizace náhorní roviny. Objekt se nachází v areálu bývalé přádelny hedvábí ve městě Tomioka v prefektuře Gunma, na ostrově Honšú v Japonsku. Konverze objekt...

  13. Web-site evaluation tools: a case study in reproductive health information.

    Science.gov (United States)

    Aslani, Azam; Pournik, Omid; Abu-Hanna, Ameen; Eslami, Saeid

    2014-01-01

    Internet forms an opportunity to inform, teach, and connect professionals and patients. However, much information on Internet is incomplete, inaccurate, or misleading, and not only in the medical domain. Because of the potential for damage from misleading and inaccurate health information, many organizations and individuals have published or implemented scoring tools for evaluating the appropriateness or quality of these resources. The objective of this study is to identify and summarize scoring tools that have evaluated web-sites providing reproductive health information in order to compare them and recommend an overarching evaluation tool. We searched Ovid MEDLINE(R) (1946 to July 2013) and OVID Embase (1980 to July 2013); and included English language studies that have evaluated the quality of websites providing reproductive health information. Studies only assessing the content of websites were excluded. We identified 5 scoring tools: 1-The HON (health on the net) Code of Conduct for medical and health Web sites, 2-Silberg scores, 3-Hogne Sandvik scale, 4-Jim Kapoun's Criteria for Evaluating Web Pages, and 5-The Health Information Technology Institute (HITI) criteria. We have compared these scales and identified 14 criteria: authorship, ownership, currency, objectivity/content, transparency/source, interactivity, privacy/ethics, financial disclosure, navigability/links, complementarity, advertising policy, design, quantity, and accessibility. We integrated these criteria and introduced a new tool with 10 criteria. Website evaluation tools differ in their evaluation criteria and there is a lack of consensus about which to use; therefore, an integrated easy to use set of criteria is needed.

  14. Using constructive alignment theory to develop nursing skills curricula.

    Science.gov (United States)

    Joseph, Sundari; Juwah, Charles

    2012-01-01

    Constructive alignment theory has been used to underpin the development of curricula in higher education for some time (Biggs and Tang, 2007), however, its use to inform and determine skills curricula in nursing is less well documented. This paper explores the use of constructive alignment theory within a study of undergraduate student nurses undertaking clinical skill acquisition in the final year of a BSc (Hons) Nursing course. Students were followed up as newly qualified nurses (NQN) (n = 58) to ascertain the impact of skill acquisition in this way. Comparisons were made with newly qualified nurses who did not participate in a constructively aligned curriculum. This mixed methods study reported skill identification within the immediate post-registration period and evaluated the constructively aligned curriculum as having positive benefits for NQNs in terms of confidence to practice. This was supported by preceptors' views. The study recommends two process models for nursing skills curriculum development and reports that constructive alignment is a useful theoretical framework for nurse educators. Copyright © 2011 Elsevier Ltd. All rights reserved.

  15. Ethanol concentration in 56 refillable electronic cigarettes liquid formulations determined by headspace gas chromatography with flame ionization detector (HS-GC-FID).

    Science.gov (United States)

    Poklis, Justin L; Wolf, Carl E; Peace, Michelle R

    2017-10-01

    Personal battery-powered vaporizers or electronic cigarettes were developed as an alternative to traditional cigarettes. The modern electronic cigarettes were patented in 2004 by Hon Lik in China. In May 2016, the US Food and Drug Administration (FDA) imposed regulatory statutes on e-cigarettes and their liquid formulations (e-liquids); prior to that, they were unregulated. E-liquids are typically composed of propylene glycol and/or glycerin, flavouring component(s), and active ingredient(s), such as nicotine. Fifty-six commercially available e-liquids, purchased from various sources, contained a variety of flavours and active ingredients. A headspace gas chromatography with flame ionization detector (HS-GC-FID) method was used to analyze these e-liquids for volatiles content. Only one of the e-liquids listed ethanol as a component. The chromatographic separation of volatiles was performed on a Restek BAC-1 column. A linear calibration was generated for ethanol with limits of detection and quantification (LOD/LOQ) of 0.05 mg/mL. Ethanol concentrations in the 56 e-liquids ranged from none detected to 206 mg/mL. The ethanol determined in these products may have been used in flavourants or a solvent; the reason for inclusion cannot be fully ascertained. The implications of vaporizing ethanol as an e-liquid component are unknown. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

  16. Quality of Web-based information on cocaine addiction.

    Science.gov (United States)

    Khazaal, Yasser; Chatton, Anne; Cochand, Sophie; Zullino, Daniele

    2008-08-01

    To evaluate the quality of web-based information on cocaine use and addiction and to investigate potential content quality indicators. Three keywords: cocaine, cocaine addiction and cocaine dependence were entered into two popular World Wide Web search engines. Websites were assessed with a standardized proforma designed to rate sites on the basis of accountability, presentation, interactivity, readability and content quality. "Health on the Net" (HON) quality label, and DISCERN scale scores aiding people without content expertise to assess quality of written health publication were used to verify their efficiency as quality indicators. Of the 120 websites identified, 61 were included. Most were commercial sites. The results of the study indicate low scores on each of the measures including content quality. A global score (the sum of accountability, interactivity, content quality and aesthetic criteria) appeared as a good content quality indicator. While cocaine education websites for patients are widespread, their global quality is poor. There is a need for better evidence-based information about cocaine use and addiction on the web. The poor and variable quality of web-based information and its possible impact on physician-patient relationship argue for a serious provider for patient talk about the health information found on Internet. Internet sites could improve their content using the global score as a quality indicator.

  17. A qualitative study exploring student midwives' experiences of carrying a caseload as part of their midwifery education in England.

    Science.gov (United States)

    Rawnson, Stella

    2011-12-01

    To explore student midwives' experiences of caseloading to develop an understanding of how they perceive this educational strategy has impacted on their learning journey to becoming a midwife. A qualitative approach drawing upon the principles of grounded theory. Data were collected by in-depth semi-structured interviews. A university in the South of England providing undergraduate pre-registration midwifery education across Advanced Diploma and BSc (Hons) programmes. Eight Caucasian female final-year student midwives aged 23-50 years who had completed their caseloading experience. One core category ('making it good') and four major categories emerged: (1) 'developing and managing caseload', (2) 'learning partnerships', (3) 'feeling like a midwife' and (4) 'afterwards'. The core category was reflected in all the other categories and was dependent upon them. Students identified caseloading as a highly beneficial learning approach, facilitating application of theory to practice and acquisition of new skills promoting confidence and competence in practice. Students articulated an overwhelming desire and concern to meet and facilitate women's expectations. Perceptions of letting the woman down evoked feelings of inadequacy and failure. Flexible working practices, on-call commitment and carrying a caseload alongside academic and home commitments was, for many, emotionally stressful. Effective preparation of students for the realities of caseloading, the development of realistic caseloads that take account of the student's individual situation, and the provision of supportive frameworks are essential. Copyright © 2010 Elsevier Ltd. All rights reserved.

  18. Gerald J. Marks, M.D., FACS (1925-), founder of the Society of American Gastrointestinal Endoscopic Surgeons (SAGES).

    Science.gov (United States)

    Yeo, Theresa P; Cowan, Scott W; Yeo, Charles J

    2018-03-01

    This historical vignette describes the professional career of Gerald J. Marks, the founder of the Society of American Gastrointestinal and Endoscopic Surgeons and the International Federation of Societies of Endoscopic Surgeons. Dr. Marks is also the founding Associate Editor of Surgical Endoscopy, which celebrated its 30th anniversary in 2017. Dr. Marks is a renowned colorectal surgeon, an accomplished watercolor artist, and a fascinating personality.

  19. The Fanconi anemia proteins FAA and FAC function in different cellular compartments to protect against cross-linking agent cytotoxicity

    NARCIS (Netherlands)

    Kruyt, FAE; Youssoufian, H

    1998-01-01

    Fanconi anemia (FA) is an autosomal recessive disease characterized by chromosomal instability, bone marrow failure, and a high risk of developing malignancies, Although the disorder is genetically heterogeneous, all FA cells are defined by their sensitivity to the apoptosis-inducing effect of

  20. Gene expression profiles of Bapx1 expressing FACS sorted cells from wildtype and Bapx1-EGFP null mouse embryos

    Directory of Open Access Journals (Sweden)

    Sumantra Chatterjee

    2015-09-01

    Full Text Available The data described in this article refers to Chatterjee et al. (2015 “In vivo genome-wide analysis of multiple tissues identifies gene regulatory networks, novel functions and downstream regulatory genes for Bapx1 and its co-regulation with Sox9 in the mammalian vertebral column” (GEO GSE35649 [1]. Transcriptional profiling combined with genome wide binding data is a powerful tool to elucidate the molecular mechanism behind vertebrate organogenesis. It also helps to uncover multiple roles of a single gene in different organs. In the above mentioned report we reveal the function of the homeobox gene Bapx1 during the embryogenesis of five distinct organs (vertebral column, spleen, gut, forelimb and hindlimb at a relevant developmental stage (E12.5, microarray analysis of isolated wildtype and mutant cells in is compared in conjunction with ChIP-Seq analysis. We also analyzed the development of the vertebral column by comparing microarray and ChIP-Seq data for Bapx1 with similarly generated data sets for Sox9 to generate a gene regulatory network controlling various facets of the organogenesis.

  1. Solution and solid-state electrochemiluminescence of a fac-tris(2-phenylpyridyl)iridium(III)-cored dendrimer

    International Nuclear Information System (INIS)

    Reid, Ellen F.; Burn, Paul L.; Lo, Shih-Chun; Hogan, Conor F.

    2013-01-01

    The solution phase and solid-state electrochemistry and electrochemiluminescence (ECL) of an iridium(III) complex-cored dendrimeric analogue of Ir(ppy) 3 , (G1pIr), are reported. The solid-state electrochemistry and solid-state ECL of Ir(ppy) 3 itself is also described for the first time. In solution phase, the dendrimer displays greater immunity to oxygen quenching in photoluminescence (PL) experiments and exhibits greater ECL efficiency compared to the parent Ir(ppy) 3 core under the same conditions, despite a lower photoluminescence quantum yield. It is proposed that the dendrons which effectively shield the core from PL quenching interactions in the solid-state counteract the effects of parasitic side-reactions during the solution ECL experiments. Electroactive and ECL-active solid-state films of both Ir(ppy) 3 and G1pIr were produced by drop-coating on boron doped diamond electrodes. Films of Ir(ppy) 3 produced stable co-reactant ECL. However, films of G1pIr produced lower than expected ECL intensity. This was attributed to poorer charge transport and the lipophilicity of the film limiting the rate of interaction with the co-reactant required for formation of the excited state

  2. Pseudosymmetric fac-di­aqua­trichlorido[(di­methyl­phosphor­yl)methanaminium-κO]manganese(II)

    Science.gov (United States)

    Reiss, Guido J.

    2013-01-01

    In the title compound, [Mn(C3H11NOP)Cl3(H2O)2], the MnII metal center has a distorted o­cta­hedral geometry, coordinated by the three chloride ligands showing a facial arrangement. Two water mol­ecules and the O-coordinated dpmaH cation [dpmaH = (di­methyl­phosphor­yl)methanaminium] complete the coordination sphere. Each complex mol­ecule is connected to its neighbours by O—H⋯Cl and N—H⋯Cl hydrogen bonds. Two of the chloride ligands and the two water ligands form a hydrogen-bonded polymeric sheet in the ab plane. Furthermore, these planes are connected to adjacent planes by hydrogen bonds from the aminium function of cationic dpmaH ligand. A pseudo-mirror plane perpendicular to the b axis in the chiral space group P21 is observed together with inversion twinning [ratio = 0.864 (5):0.136 (5)]. PMID:23723764

  3. Applicability of the “Gallet equation” to the vegetation clearances of NERC Reliability Standard FAC-003-2

    Energy Technology Data Exchange (ETDEWEB)

    Kirkham, Harold

    2012-03-31

    NERC has proposed a standard to use to specify clearances between vegetation and power lines. The purpose of the rule is to reduce the probability of flashover to a calculably low level. This report was commissioned by FERC’s Office of Electrical Reliability. The scope of the study was analysis of the mathematics and documentation of the technical justification behind the application of the Gallet equation and the assumptions used in the technical reference paper

  4. Propuesta de programa educativo en la FAC orientado a la seguridad aérea e industrial

    Directory of Open Access Journals (Sweden)

    Iván Mauricio Hincapié Álvarez

    2007-01-01

    Full Text Available El Estado y directamente la Fuerza Aérea Colombiana invierten recursos para la formación, instrucción y entrenamiento del personal perteneciente a la Fuerza para el cumplimiento de su misión en las diferentes áreas de participación.

  5. Identification of Salmonella Typhimurium-specific DNA aptamers developed using whole-cell SELEX and FACS analysis.

    Science.gov (United States)

    Moon, Jihea; Kim, Giyoung; Lee, Sangdae; Park, Saetbyeol

    2013-11-01

    Conventional methods for detection of infective organisms, such as Salmonella, are complicated and require multiple steps, and the need for rapid detection has increased. Biosensors show great potential for rapid detection of pathogens. In turn, aptamers have great potential for biosensor assay development, given their small size, ease of synthesis and labeling, lack of immunogenicity, a lower cost of production than antibodies, and high target specificity. In this study, ssDNA aptamers specific to Salmonella Typhimurium were obtained by a whole bacterium-based systematic evolution of ligands by exponential enrichment (SELEX) procedure and applied to probing S. Typhimurium. After 10 rounds of selection with S. Typhimurium as the target and Salmonella Enteritidis, Escherichia coli and Staphylococcus aureus as counter targets, the highly enriched oligonucleic acid pool was sorted using flow cytometry. In total, 12 aptamer candidates from different families were sequenced and grouped. Fluorescent analysis demonstrated that aptamer C4 had particularly high binding affinity and selectivity; this aptamer was then further characterized. © 2013 Elsevier B.V. All rights reserved.

  6. Side effects of radiotherapy in breast cancer patients. The Internet as an information source

    Energy Technology Data Exchange (ETDEWEB)

    Janssen, S. [Medical Practice for Radiotherapy and Radiation Oncology, Hannover (Germany); University of Luebeck, Department of Radiation Oncology, Luebeck (Germany); Kaesmann, L.; Rades, D. [University of Luebeck, Department of Radiation Oncology, Luebeck (Germany); Fahlbusch, F.B. [Friedrich-Alexander-University of Erlangen-Nuernberg, Department of Pediatrics and Adolescent Medicine, Erlangen (Germany); Vordermark, D. [University Hospital Halle (Saale), Department of Radiation Oncology, Halle (Saale) (Germany)

    2018-02-15

    ] Brustkrebs ist der haeufigste Tumor bei Frauen, der eine adjuvante Strahlentherapie notwendig macht. Da das Internet eine wesentliche Informationsquelle fuer Krebspatienten geworden ist, hat diese Untersuchung das Ziel, die Qualitaet der Webseiten mit Informationen zu Nebenwirkungen einer Strahlentherapie bei Brustkrebs zu evaluieren. Mit Hilfe der Suchmaschine Google wurde eine patientenorientierte Suche englisch- und deutschsprachiger Webseiten mit den Suchbegriffen ''Brustkrebs-Strahlentherapie - Nebenwirkungen'' und ''Breast cancer - radiotherapy - side effects'' an zwei verschiedenen Zeitpunkten durchgefuehrt. Die ersten 30 Treffer wurden anhand des validierten 16-Fragen DISCERN-Plus-Scores, der HON-Code-Zertifizierung (''Health on the Net Code of Conduct'') und den JAMA-Kriterien (''Journal of the American Medical Association'') untersucht. Die Gesamtqualitaet der untersuchten Seiten (DISCERN-Score) wurde im Weiteren mit einer separaten Analyse der Suchmaschinen Bing und Yahoo verglichen. Waehrend die allgemeine Qualitaet der Internetseiten (DISCERN-Score) eine grosse Bandbreite zeigte, waren die Ergebnisse mehrheitlich von maessiger bis schlechter Qualitaet. Englischsprachige Webseiten zeigten signifikant bessere Ergebnisse, insbesondere Seiten von Krankenhaeusern, Universitaeten sowie Nicht-Regierungs-Organisationen. Nur eine Minderheit erfuellte alle 4 JAMA-Kriterien und war HON-Code-zertifiziert (beide Sprachen). Die Google-Suche zu unterschiedlichen Zeitpunkten zeigte unter den ersten zehn Treffern keine wesentlichen Unterschiede. Signifikante Variationen traten erst bei hinteren Treffern auf. Der Vergleich unterschiedlicher Suchmaschinen ergab aehnliche DISCERN-Score-Ergebnisse. Durch das Internet koennen sich Patienten auf der Suche nach Informationen zur Strahlentherapie einen Ueberblick verschaffen. Basierend auf der aktuell geringen Qualitaet der Internetseiten und der fehlenden

  7. On the intramolecular origin of the blue shift of A-H stretching frequencies: triatomic hydrides HAX.

    Science.gov (United States)

    Karpfen, Alfred; Kryachko, Eugene S

    2009-04-30

    A series of intermolecular complexes formed between the triatomic hydrides HAX and various interaction partners are investigated computationally aiming (1) to demonstrate that either an appearance or nonappearance of a blue shift of the A-H stretching frequency is directly related to the sign of the intramolecular coupling that exists between the two degrees of freedom, the A-H and A-X bond lengths, and (2) to offer the following conjecture: the theoretical protonation of a triatomic neutral molecule HAX at the site X is a simple and rather efficient probe of a red or blue shift that the stretching frequency nu(A-H) undergoes upon complex formation regardless of whether this bond is directly involved in hydrogen bonding or not. In other words, to predict whether this A-H bond is capable to display a blue or red shift of nu(A-H), it suffices to compare the equilibrium structures and vibrational spectra of a given molecule with its protonated counterpart. The two above goals are achieved invoking a series of 11 triatomic molecules: HNO, HSN, HPO, and HPS characterized by a negative intramolecular coupling; HON and HNS as intermediate cases; and HOF, HOCl, HCN, HNC, and HCP with a positive intramolecular coupling. For these purposes, the latter molecules are investigated at the MP2/6-311++G(2p,2d) level in the neutral and protonated HAXH(+) forms as well as their complexes with H(2)O and with the fluoromethanes H(3)CF, H(2)CF(2), and HCF(3).

  8. Introducing a gender-neutral pronoun in a natural gender language: the influence of time on attitudes and behavior.

    Science.gov (United States)

    Gustafsson Sendén, Marie; Bäck, Emma A; Lindqvist, Anna

    2015-01-01

    The implementation of gender fair language is often associated with negative reactions and hostile attacks on people who propose a change. This was also the case in Sweden in 2012 when a third gender-neutral pronoun hen was proposed as an addition to the already existing Swedish pronouns for she (hon) and he (han). The pronoun hen can be used both generically, when gender is unknown or irrelevant, and as a transgender pronoun for people who categorize themselves outside the gender dichotomy. In this article we review the process from 2012 to 2015. No other language has so far added a third gender-neutral pronoun, existing parallel with two gendered pronouns, that actually have reached the broader population of language users. This makes the situation in Sweden unique. We present data on attitudes toward hen during the past 4 years and analyze how time is associated with the attitudes in the process of introducing hen to the Swedish language. In 2012 the majority of the Swedish population was negative to the word, but already in 2014 there was a significant shift to more positive attitudes. Time was one of the strongest predictors for attitudes also when other relevant factors were controlled for. The actual use of the word also increased, although to a lesser extent than the attitudes shifted. We conclude that new words challenging the binary gender system evoke hostile and negative reactions, but also that attitudes can normalize rather quickly. We see this finding very positive and hope it could motivate language amendments and initiatives for gender-fair language, although the first responses may be negative.

  9. Web-based information on the treatment of oral leukoplakia - quality and readability.

    Science.gov (United States)

    Wiriyakijja, Paswach; Fedele, Stefano; Porter, Stephen; Ni Riordain, Richeal

    2016-09-01

    To categorise the content and assess the quality and readability of the online information regarding the treatment for oral leukoplakia. An online search using the term 'leukoplakia treatment' was carried out on 8th June 2015 using the Google search engine. The content, quality and readability of the first 100 sites were explored. The quality of the web information was assessed using the following tools, the DISCERN instrument and the Journal of the American Medical Association (JAMA) benchmarks for website analysis and the HON seal. Readability was assessed via the Flesch Reading Ease Score. The search strategy generated 357 000 sites on the Google search engine. Due to duplicate links, non-operating links and irrelevant links, a total of 47 of the first 100 websites were included in this study. The mean overall rating achieved by included websites using the DISCERN instrument was 2.3. With regard to the JAMA benchmarks, the vast majority of examined websites (95.7%) completely fulfilled the disclosure benchmark and less than 50% of included websites met the three remaining criteria. A mean total readability score of 47.5 was recorded with almost 90% of websites having a readability level ranging from fairly difficult to very difficult. Based on this study, the online health information regarding oral leukoplakia has challenging readability with content of questionable accuracy. As patients often search for health information online, it would be prudent for clinicians to highlight the caution with which online information should be interpreted. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  10. Efecto de la aplicación de azufre para el control de oidiosis “leveillula taurica” en el cultivo de alcachofa (Cynara scolymus L. var. imperial star

    Directory of Open Access Journals (Sweden)

    L. Mauricio

    2011-01-01

    Full Text Available Una de las causas importantes para el decaimiento de la producción de alcachofa es por la enfermedad conocida con el nombre de oídium u oidiosis o ceniza, “ Leveillula taurica” , la q ue provoca formaciones pulverulentas en el envés de las hojas, y luego invaden el haz.; induciendo a una pérdida de masa foliar, muerte de la planta y reducción en rendimiento. Con la finalidad de poder contrarrestar el efecto de infección y avance del hon go se planteo el trabajo de investigación la cuál fue determinar la dosis adecuada del azufre para el control de oidiosis ( Leveillula taurica en el cultivo de alcachofa Cynara scolymus L var. imperial star. El experimento fue llevado a cabo en el Distrit o de Víctor Larco, Trujillo, La Libertad; suelo de textura franco arcilloso, empleándose un sistema de riego por gravedad cuya frecuencia de riego es quincenal para la conducción del cultivo. Se empleó un Diseño de Bloques Completos al Azar, con cuatro tr atamientos y un testigo, y con cuatro repeticiones. Fue realizado un análisis de varianza y la prueba de Duncan con un nivel de significancia de 5 %. Los resultados mostraron que los tratamientos aplicados de azufre reducen y controlan el avance del hongo , siendo el mejor el T2, con dosis 1 kg/cil. Se concluye que estos tratamientos son adecuados para ser aplicados en el cultivo de alcachofa para el control de oídium ( Leveillula taurica.

  11. Evaluación de la calidad ética y del contenido de los recursos online para padres

    Directory of Open Access Journals (Sweden)

    2018-01-01

    Full Text Available La calidad de los recursos online para padres que permiten acceder al conocimiento en abierto apenas ha recibido atención a pesar de su incremento. Este estudio analiza la calidad tanto ética como de contenido de dichos recursos. Los criterios éticos están basados en los de «Salud en la Red» (HON, mientras que los de contenido se basan en los principios de la Parentalidad Positiva y la efectividad de los materiales de aprendizaje usados. Los criterios se aplicaron a una muestra de webs internacionales (n=100 para padres y madres hispanohablantes. Los análisis de Chicuadrado mostraron que los sitios web españoles, de empresas oficiales e informativos obtuvieron una calificación más alta en los criterios éticos que los recursos de Sudamérica, de padres e interactivos, en privacidad, autoridad, justificabilidad e información financiera. El Análisis Jerárquico de Clúster aplicado a los criterios de contenido mostró que los sitios web de alta calidad, a diferencia de los de baja calidad, valoraban la igualdad de género, un rol parental positivo, modelaban una variedad de prácticas parentales, contenidos educativos con formatos multimedia y proporcionaban experiencias, información académica y técnicas. La privacidad, la información financiera, y la justificabilidad eran más característicos de los clúster con contenidos de Alta y Media calidad. En conclusión, el estudio ilustra algunos de los retos del conocimiento en abierto y define las áreas prioritarias para la mejora de la calidad para los diseñadores de webs y para los profesionales que quieran ayudar a los padres a desarrollar habilidades para buscar fuentes confiables

  12. Identifying applicants suitable to a career in nursing: a value-based approach to undergraduate selection.

    Science.gov (United States)

    Traynor, Marian; Galanouli, Despina; Roberts, Martin; Leonard, Lawrence; Gale, Thomas

    2017-06-01

    The aim of this study was to complement existing evidence on the suitability of Multiple Mini Interviews as a potential tool for the selection of nursing candidates on to a BSc (Hons) nursing programme. This study aimed to trial the Multiple Mini Interview approach to recruitment with a group of first year nursing students (already selected using traditional interviews). Cross-sectional validation study. This paper reports on the evaluation of the participants' detailed scores from the Multiple Mini Interview stations; their original interview scores and their end of year results. This study took place in March 2015. Scores from the seven Multiple Mini Interview stations were analysed to show the internal structure, reliability and generalizability of the stations. Original selection scores from interviews and in-course assessment were correlated with the MMI scores and variation by students' age, gender and disability status was explored. Reliability of the Multiple Mini Interview score was moderate (G = 0·52). The Multiple Mini Interview score provided better differentiation between more able students than did the original interview score but neither score was correlated with the module results. Multiple Mini Interview scores were positively associated with students' age but not their gender or disability status. The Multiple Mini Interview reported in this study offers a selection process that is based on the values and personal attributes regarded as desirable for a career in nursing and does not necessarily predict academic success. Its moderate reliability indicates the need for further improvement but it is capable of discriminating between candidates and shows little evidence of bias. © 2016 John Wiley & Sons Ltd.

  13. Available web-based teaching resources for health care professionals on screening for oral cancer

    Science.gov (United States)

    Varela-Centelles, Pablo; Insua, Angel; Warnakulasuriya, Saman; Rapidis, Alexander; Diz, Pedro; Seoane, Juan

    2015-01-01

    Objectives: To identify websites with adequate information on oral cancer screening for healthcare professionals (HCPs) and to assess both their quality and contents. Study Design: Websites were identified using Google and HON medical professional search engines using the terms “screening for oral cancer”. The first 100 sites retrieved by each engine were analysed using the DISCERN questionnaire (reliability), the V instrument (contents on oral cancer) and further by the Flesch-Kinkaid Reading Grade Level and the Flesch Reading Ease (readability). Results: The overall rating showed minimal shortcomings in the quality of the information in the websites. The coverage and correctness of information on “visual examination” was rated as fair/good, whereas updating of contents resulted very variable (eg: 81% for visual examination and 18.2% for molecular biomarkers). These results permitted to rank the websites housing relevant information for oral cancer. Top ranking websites were affiliated to the Oral Cancer Foundation (USA), WHO Collaborating Centre for oral cancer (UK) whose webpage is entitled “Oral Cancer Education and Research”, and the Clinical Guidelines maintained by the British Columbia Cancer Agency (Canada) and the British Dental Association (UK) respectively. Conclusions: There are web-based, HCP-addressed, resources on screening for oral cancer housing heterogeneous information both in quality and contents. The use of specific evaluation tools permits the selection of reliable websites on this topic with a potential to improve the existing educational gaps among HCPs. Key words:Oral cancer, early diagnosis, screening, secondary prevention, internet, teaching resources, continuous education. PMID:25475775

  14. Non-Invasive Seismic Methods for Earthquake Site Classification Applied to Ontario Bridge Sites

    Science.gov (United States)

    Bilson Darko, A.; Molnar, S.; Sadrekarimi, A.

    2017-12-01

    How a site responds to earthquake shaking and its corresponding damage is largely influenced by the underlying ground conditions through which it propagates. The effects of site conditions on propagating seismic waves can be predicted from measurements of the shear wave velocity (Vs) of the soil layer(s) and the impedance ratio between bedrock and soil. Currently the seismic design of new buildings and bridges (2015 Canadian building and bridge codes) requires determination of the time-averaged shear-wave velocity of the upper 30 metres (Vs30) of a given site. In this study, two in situ Vs profiling methods; Multichannel Analysis of Surface Waves (MASW) and Ambient Vibration Array (AVA) methods are used to determine Vs30 at chosen bridge sites in Ontario, Canada. Both active-source (MASW) and passive-source (AVA) surface wave methods are used at each bridge site to obtain Rayleigh-wave phase velocities over a wide frequency bandwidth. The dispersion curve is jointly inverted with each site's amplification function (microtremor horizontal-to-vertical spectral ratio) to obtain shear-wave velocity profile(s). We apply our non-invasive testing at three major infrastructure projects, e.g., five bridge sites along the Rt. Hon. Herb Gray Parkway in Windsor, Ontario. Our non-invasive testing is co-located with previous invasive testing, including Standard Penetration Test (SPT), Cone Penetration Test and downhole Vs data. Correlations between SPT blowcount and Vs are developed for the different soil types sampled at our Ontario bridge sites. A robust earthquake site classification procedure (reliable Vs30 estimates) for bridge sites across Ontario is evaluated from available combinations of invasive and non-invasive site characterization methods.

  15. Autoimmune Hemolytic Anemia as a Complication of Nivolumab Therapy.

    Science.gov (United States)

    Palla, Amruth R; Kennedy, Devin; Mosharraf, Hossain; Doll, Donald

    2016-01-01

    Recently, immunotherapeutic drugs, including PD-1 inhibitors (nivolumab, pembrolizumab), PD-L1 inhibitors (atezolizumab, avelumab), and CTLA4 inhibitors (ipiliumumab), have emerged as important additions to the armamentarium against certain malignancies and have been incorporated into therapeutic protocols for first-, second-, or third-line agents for these metastatic cancers. Immune checkpoint inhibitor nivolumab is currently FDA approved for the treatment of patients with metastatic malignant melanoma [Redman et al.: BMC Med 2016;14: 20], metastatic non-small cell lung cancer [Guibert and Mazières: Expert Opin Biol Ther 2015;15: 1789-1797], metastatic renal cell cancer [Farolfi et al.: Expert Opin Drug Metab Toxicol 2016;12: 1089-1096], and relapsed or refractory classic Hodgkin's lymphoma [Villasboas and Ansell: Expert Rev Anticancer Ther 2016;16: 5-12]. Given the current and increasing indications for these drugs, it is essential for all physicians to become well versed with their common adverse effects and to be observant for other less documented clinical conditions that could be unmasked with the use of such medications. A definite association between autoimmune hemolytic anemia and the immune checkpoint inhibitor nivolumab has not been clearly documented, although a few cases have been reported recently [Kong et al.: Melanoma Res 2016;26: 202-204; Schwab et al.: Case Rep Oncol 2016;9: 373-378; Tardy et al.: Hematol Oncol 2016, DOI: 10.1002/hon.2338]. We report a case of fatal autoimmune hemolytic anemia refractory to steroids in a patient treated with nivolumab for metastatic lung cancer, and reflect on the other reported cases of autoimmune hemolytic anemia after the use of nivolumab.

  16. Low-temperature Synthesis of Tin(II) Oxide From Tin(II) ketoacidoximate Precursor

    KAUST Repository

    Alshankiti, Buthainah

    2015-04-01

    Sn (II) oxide finds numerous applications in different fields such as thin film transistors1, solar cells2 and sensors.3 In this study we present the fabrication of tin monoxide SnO by using Sn (II) ketoacid oximate complexes as precursors. Tin (II) ketoacidoximates of the type [HON=CRCOO]2Sn where R= Me 1, R= CH2Ph 2, and [(MeON=CMeCOO)3Sn]- NH4 +.2H2O 3 were synthesized by in situ formation of the ketoacid oximate ligand. The crystal structures were determined via single crystal X- ray diffraction of the complexes 1-3 revealed square planar and square pyramidal coordination environments for the Sn atom. Intramolecular hydrogen bonding is observed in all the complexes. Furthermore, the complexes were characterized by Infrared (IR), Nuclear Magnetic Resonance (NMR) and elemental analysis. From thermogravimetric analysis of 1-3, it was found that the complexes decomposed in the range of 160 – 165 oC. Analysis of the gases evolved during decomposition indicated complete loss of the oximato ligand in one step and the formation of SnO. Spin coating of 1 on silicon or glass substrate show uniform coating of SnO. Band gaps of SnO films were measured and found to be in the range of 3.0 – 3.3 eV by UV-Vis spectroscopy. X-ray photoelectron spectroscopy indicated surface oxidation of the SnO film. Heating 1 above 140 oC in air gives SnO of size ranging from 10 – 500 nm and is spherical in shape. The SnO nanomaterial is characterized by powder X-ray diffraction(XRD), Raman spectroscopy, Scanning Electron Microscopy (SEM), and Transmission Electron Microscopy (TEM).

  17. Supporting socialisation in the transition to university: A potential use for on-line discussion boards

    International Nuclear Information System (INIS)

    Robinson, Leslie; Reeves, Pauline; Murphy, Fred; Hogg, Peter

    2010-01-01

    Background: Promoting socialisation for students entering Higher Education is desirable on two grounds. In the first instance it facilitates the processes of student collaboration which, according to sociocultural pedagogies, is important for effective learning. Secondly, it provides a supportive social network, enhancing the student experience which is thought to reduce the risk of attrition. These two drivers provided the rationale for our work. Method: Using the Blackboard Virtual Learning Environment, two on-line discussion boards were used during the transition and induction period for the BSc (Hons) Diagnostic Radiography programme at the University of Salford. The aim was to facilitate socialisation between students about to embark on the programme and current students and staff. The use of discussion boards was evaluated using a mixed methods approach. Statistical data regarding postings was analysed. Posts and focus group comments were subject to content analysis. Results: The discussion boards were 'hit' 5718 times and there were 280 posts. A small number of students did not post any messages. There was evidence of the key features of on-line socialisation which were; establishing an identity; getting to know others; discovering and contributing to communication etiquette; and developing supporting and trusting relationships. Conclusion: The discussion boards were deemed a successful method of providing socialisation during transition and induction. There were some limitations with discussion board layout and functionality and a blog, with its chronological layout and capability to display visual cues such as emoticons may be more effective. The limited participation by some students may provide a means by which to identify 'at-risk' students before the start of the course and this would be an interesting area for further study.

  18. [A study of treatise on medicine by King Sejo].

    Science.gov (United States)

    Hwang, Im-kyung; Hwang, Sang-lk

    2003-12-01

    This paper explores historical backgrounds and contents of Treatise on Medicine written by King Sejo (r. 1455-1468) including his views on traditional medicine and pharmacy in the early Chosen period. The Treatise declared by King Sejo in 1463 has been considered as an important and unique manual of medicine because it was the exclusive example written by the king of Chosen. It was the King Sejo' s era when the medical milieu in both social and medical aspects was highly encouraged thanks to the previous achievements by King Sejong the Great (r.1418-1450). King Sejo, in particular, who was much interested in practical learning called 'Miscellaneous Studies', emphasized on court medicine. His writing can be understood in such historical frame. Another reason why he wrote the Treatise can be said that he felt necessary for establishing the medical ethic codes for inefficient court medicine-officials. In personal background, he tried to find available remedies since he had been suffered from some chronic diseases. The contents of the Treatise can be broadly fallen to the clinical and ethical aspects. In the former one, the Treatise focuses on treatment without hesitation through the sharp and exact diagnosis by medical doctors. In the latter one, eight categories of medical doctors are discussed according to their moral degrees: sim'eui, sik'eui, yak'eui, hon'eui, kwang eui, mang'eui, sa'eui, and sal'eui. Finally, musim' ji-eui was supplemented. Among them, sal'eui, medicine-official lacking both medical ability and ethical attitude, was classified as the lowest degree; sim'eui, medicine-official sincerely making his all efforts for patients, was thought to be a paragon of medical morality. In conclusion, the Treatise on Medicine by King Sejo played an important role as a manual for the principle of medical practice and for the instruction to enhance ethical attitude among medicine-officials.

  19. The adsorption of nitrogen oxides on crystalline ice

    Directory of Open Access Journals (Sweden)

    T. Bartels

    2002-01-01

    Full Text Available The partitioning of nitrogen oxides between ice and air is of importance to the ozone budget in the upper troposphere. In the present study, adsorption of nitrogen oxides on ice was investigated at atmospheric pressure using a chromatographic technique with radioactively labelled nitrogen oxides at low concentrations. The measured retentions solely depended on molecular adsorption and were not influenced by dimerisation, formation of encapsulated hydrates on the ice surface, dissociation of the acids, nor by migration into a quasi-liquid layer or grain boundaries. Based on the chromatographic retention and the model of thermo-chromatography, the standard adsorption enthalpy of -20 kJ mol-1 for NO, -22kJ mol-1 for NO2, -30kJ mol-1 for peroxyacetyl nitrate, -32kJ mol-1 for HON} and -44 kJ mol-1 for HNO3 was calculated. To perform those calculations within the model of thermo-chromatography, the standard adsorption entropy was calculated based on statistical thermodynamics. In this work, two different choices of standard states were applied, and consequently different values of the standard adsorption entropy, of either between -39 kJ mol-1 and -45kJ mol-1, or -164 kJ mol-1 and -169 kJ mol-1 for each nitrogen oxide were derived. The standard adsorption enthalpy was identical for both standard adsorption entropies and thus shown to be independent of the choice of standard state. A brief outlook on environmental implications of our findings indicates that adsorption on ice might be an important removal process of HNO3. In addition, it might be of some importance for HONO and peroxyacetyl nitrate and irrelevant for NO and NO2.

  20. Reflective writing: the student nurse's perspective on reflective writing and poetry writing.

    Science.gov (United States)

    Coleman, Dawn; Willis, Diane S

    2015-07-01

    Reflective writing is a mandatory part of nurse education but how students develop their skills and use reflection as part of their experiential learning remains relatively unknown. Understanding reflective writing in all forms from the perspective of a student nurse is therefore important. To explore the use of reflective writing and the use of poetry in pre-registered nursing students. A qualitative design was employed to explore reflective writing in pre-registered nursing students. A small university in Scotland. BSc (Hons) Adult and Mental Health Pre-registration Student Nurses. Two focus groups were conducted with 10 student nurses during March 2012. Data was analysed thematically using the framework of McCarthy (1999). Students found the process of reflective writing daunting but valued it over time. Current educational methods, such as assessing reflective accounts, often lead to the 'narrative' being watered down and the student feeling judged. Despite this, reflection made students feel responsible for their own learning and research on the topic. Some students felt the use of models of reflection constricting, whilst poetry freed up their expression allowing them to demonstrate the compassion for their patient under their care. Poetry writing gives students the opportunity for freedom of expression, personal satisfaction and a closer connection with their patients, which the more formal approach to reflective writing did not offer. There is a need for students to have a safe and supportive forum in which to express and have their experiences acknowledged without the fear of being judged. Crown Copyright © 2015. Published by Elsevier Ltd. All rights reserved.

  1. Low temperature X-ray structure analyses combined with NBO studies of a new heteroleptic octa-coordinated Holmium(III) complex with N,N,N-tridentate hydrazono-phthalazine-type ligand

    Science.gov (United States)

    Soliman, Saied M.; El-Faham, Ayman

    2018-04-01

    The new heteroleptic [HoL(H2O)5]Br3 complex, L is hydrazono-phthalazine ligand, is synthesized and its molecular structure aspects were analyzed using single crystal X-ray structure (SCXRD), Hirshfeld (HF) analysis, quantum theory of atoms in molecules (QTAIM) and natural bond orbital (NBO) method. The SCXRD showed that the Ho is octa-coordinated with one N,N,N-tridentate ligand L and five water molecules. The HF analysis is used to analyze the molecular packing in the [HoL(H2O)5]Br3crystal structure. The complex cations are connected via strong Osbnd H⋯Br and Nsbnd H⋯Br H-bonding interactions which have greater importance than the Csbnd H⋯Br contacts. Also, all the Hosbnd N and Hosbnd O bonds have the characteristics of closed shell interactions using QTAIM. The natural orbitals included in these interactions were analyzed using NBO method. The alpha LP*(8)Ho and beta LP*(4)Ho which have mainly s-orbital characters are the most important anti-bonding natural orbitals included in all Ho-N and Hosbnd O bonds. The rest of the Ho anti-bonding orbitals which have either p or d-orbital characters shared partially in the Ho-ligands interactions. Natural charges analysis revealed the presence of significant amount of electron density (0.9225-0.9300 e) transferred from the ligands to Ho (2.0700-2.0775 e). Spherical spin density with ∼4.0 e is predicted over the Ho atom.

  2. Consumerism and its impact on robotic-assisted radical prostatectomy.

    Science.gov (United States)

    Alkhateeb, Sultan; Lawrentschuk, Nathan

    2011-12-01

    • Many experts consider that media coverage, marketing and/or direct-to-consumer advertising, particularly Internet-based forms, are fundamental to the widespread adoption of robotic-assisted prostatectomy (RARP). However, this has not been explored previously. • The primary objective of the present study was to delineate the role of media coverage and marketing of RARP on the Internet, whereas the secondary goal focused on website quality with respect to the presentation of prostatectomy. • Website content was evaluated for direct-to-consumer advertising after the retrieval of the first 50 websites using Google and Yahoo for each of the terms: 'robotic prostatectomy, laparoscopic prostatectomy (LP) and open radical prostatectomy (ORP)'. • A linear regression analysis was performed for the annual number of Internet news hits over the last decade for each procedure. Website quality assessment was performed using WHO Honesty on the Internet (HON) code principles. • Of the retrieved sites, the proportion containing direct-to-consumer advertising for RARP vs LP vs ORP using Google was 64% vs 14% vs 0%, respectively (P 0.05). • Media coverage and marketing of RARP on the Internet is more widespread compared to LP and ORP. • Disturbingly, the quality of websites using any technique for prostatectomy was of poor quality when using principles of honest information presenting and such findings need to be discussed with respect to obtaining informed consent from patients. © 2011 THE AUTHORS. BJU INTERNATIONAL © 2011 BJU INTERNATIONAL.

  3. Quality of Web-based information on obsessive compulsive disorder

    Directory of Open Access Journals (Sweden)

    Klila H

    2013-11-01

    Full Text Available Hedi Klila,1 Anne Chatton,2 Ariane Zermatten,2 Riaz Khan,2 Martin Preisig,1,3 Yasser Khazaal2,4 1Department of Psychiatry, Lausanne University Hospital, Lausanne, Switzerland; 2Department of Mental Health and Psychiatry, Geneva University Hospitals, Geneva, Switzerland; 3Lausanne University, Lausanne, Switzerland; 4Geneva University, Geneva, Switzerland Background: The Internet is increasingly used as a source of information for mental health issues. The burden of obsessive compulsive disorder (OCD may lead persons with diagnosed or undiagnosed OCD, and their relatives, to search for good quality information on the Web. This study aimed to evaluate the quality of Web-based information on English-language sites dealing with OCD and to compare the quality of websites found through a general and a medically specialized search engine. Methods: Keywords related to OCD were entered into Google and OmniMedicalSearch. Websites were assessed on the basis of accountability, interactivity, readability, and content quality. The "Health on the Net" (HON quality label and the Brief DISCERN scale score were used as possible content quality indicators. Of the 235 links identified, 53 websites were analyzed. Results: The content quality of the OCD websites examined was relatively good. The use of a specialized search engine did not offer an advantage in finding websites with better content quality. A score ≥16 on the Brief DISCERN scale is associated with better content quality. Conclusion: This study shows the acceptability of the content quality of OCD websites. There is no advantage in searching for information with a specialized search engine rather than a general one. Practical implications: The Internet offers a number of high quality OCD websites. It remains critical, however, to have a provider–patient talk about the information found on the Web. Keywords: Internet, quality indicators, anxiety disorders, OCD, search engine

  4. Autoimmune Hemolytic Anemia as a Complication of Nivolumab Therapy

    Directory of Open Access Journals (Sweden)

    Amruth R. Palla

    2016-11-01

    Full Text Available Recently, immunotherapeutic drugs, including PD-1 inhibitors (nivolumab, pembrolizumab, PD-L1 inhibitors (atezolizumab, avelumab, and CTLA4 inhibitors (ipiliumumab, have emerged as important additions to the armamentarium against certain malignancies and have been incorporated into therapeutic protocols for first-, second-, or third-line agents for these metastatic cancers. Immune checkpoint inhibitor nivolumab is currently FDA approved for the treatment of patients with metastatic malignant melanoma [Redman et al.: BMC Med 2016;14: 20], metastatic non-small cell lung cancer [Guibert and Mazières: Expert Opin Biol Ther 2015;15: 1789–1797], metastatic renal cell cancer [Farolfi et al.: Expert Opin Drug Metab Toxicol 2016;12: 1089–1096], and relapsed or refractory classic Hodgkin’s lymphoma [Villasboas and Ansell: Expert Rev Anticancer Ther 2016;16: 5–12]. Given the current and increasing indications for these drugs, it is essential for all physicians to become well versed with their common adverse effects and to be observant for other less documented clinical conditions that could be unmasked with the use of such medications. A definite association between autoimmune hemolytic anemia and the immune checkpoint inhibitor nivolumab has not been clearly documented, although a few cases have been reported recently [Kong et al.: Melanoma Res 2016;26: 202–204; Schwab et al.: Case Rep Oncol 2016;9: 373–378; Tardy et al.: Hematol Oncol 2016, DOI: 10.1002/hon.2338]. We report a case of fatal autoimmune hemolytic anemia refractory to steroids in a patient treated with nivolumab for metastatic lung cancer, and reflect on the other reported cases of autoimmune hemolytic anemia after the use of nivolumab.

  5. An investigation into breast imaging as part of the undergraduate (UG) education of diagnostic radiography students in the UK

    International Nuclear Information System (INIS)

    Strudwick, R.M.; Taylor, K.

    2017-01-01

    Introduction: How mammography is incorporated into undergraduate (UG) radiography training may influence student perception of the speciality and its potential as a future career option. An overview is provided of the academic and clinical content of UG radiography courses relating to mammography across the UK. Methods: Using mixed methods and an iterative, inductive approach supplying quantitative and qualitative data, we identify any variations and discuss possible causes which may help influence future training strategies. A self-designed questionnaire containing open and closed questions was sent online using SurveyMonkey™ to course leaders of all Higher Education Institutions (HEIs) offering BSc (Hons) Diagnostic Radiography courses in the UK. Responses were analysed for trends which were further explored by semi structured telephone interviews. These were transcribed and evaluated using a thematic analysis, the themes being categorised and coded. Results: 19 of 24 (79%) HEIs responded to the questionnaire. Follow up telephone interviews were conducted with five course leaders to further explore themes. Academic teaching ranged from 3 to 25 h over the 3 year course. Compared to other specialities 10 (53%) HEIs spent less time on mammography with 12 (63%) citing HCPC standards as the reason. 11 (65%) HEIs sent students on mammography placements, 2 (12%) sent females only. Placement times ranged between 2 days and 2 weeks. Influences included availability of expert teaching and relationship with clinical departments. Conclusion: There is variation in undergraduate exposure to mammography. Students views should be sought to add validity to these findings - Highlights: • A summary of undergraduate (UG) breast imaging in the UK. • Themes around the delivery of UG breast imaging education in university and practice. • Opinions of UG course leaders and other stakeholders about UG breast imaging education. • There is a variation across UK universities in

  6. Bacterial endogenous endophthalmitis in Vietnam: a randomized controlled trial comparing vitrectomy with silicone oil versus vitrectomy alone

    Directory of Open Access Journals (Sweden)

    Do T

    2014-08-01

    Full Text Available Tan Do,1 Do N Hon,1 Tin Aung,2 Nguyen DTN Hien,1 Claude L Cowan Jr3 1Vietnam National Institute of Ophthalmology, Hanoi, Vietnam; 2Singapore National Eye Center, Singapore; 3Georgetown University Medical Center, Washington, DC, USA Background/aims: To compare treatment outcomes with and without silicone oil tamponade in patients undergoing pars plana vitrectomy (PPV for severe endogenous bacterial endophthalmitis (BEE. Methods: One hundred and eight consecutive patients with severe BEE (defined by the absence of pupil red reflex at presentation and/or dense vitreous opacity on ultrasound and no improvement after 24–36 hours of medical treatment were randomly assigned to two treatment groups: Group 1, standard PPV with intravitreal antibiotics; and Group 2, PPV with intravitreal antibiotics and silicone tamponade. Overall success was defined as: a visual acuity ≥ count fingers at 1 meter, with an attached retina, and no intraocular oil. Results: Fifty three patients were randomized to Group 1 and 55 patients to Group 2. The mean age of study subjects was 32 years and baseline clinical characteristics were similar in both groups. At the final follow-up visit at 9 months, the overall success rate of Group 2 (67.3% was significantly better than Group 1 (43.4%; P=0.01. There were also fewer devastating complications (such as inoperable retinal detachment, phthisis bulbi in Group 2 compared with Group 1 (21.8% versus 43.4%; P=0.01. Conclusion: The outcome at 9 months of patients with BEE treated by vitrectomy with silicone oil was better than those treated by vitrectomy alone. Keywords: bacterial endogenous endophthalmitis, vitrectomy, silicone oil endotamponade, randomized controlled trial

  7. A critical evaluation of student radiographers' experience of the transition from the classroom to their first clinical placement

    International Nuclear Information System (INIS)

    Hyde, Emma

    2015-01-01

    Introduction: Students studying for qualifications which enable them to apply for registration as health care professionals are expected to undertake a large amount of clinical placement to support their learning. The BSc Hons Diagnostic Radiography at one post-1992 UK University is no exception. It was identified in a previous study by this researcher that a relatively large number of first year student radiographers were unsure, or nervous, about some aspects of the transition to their first clinical placement. It was felt that further investigation into the student experience of the transition to the first clinical placement was warranted. Methodology: A mixed-methods survey approach was used to elicit quantitative and qualitative data from current radiography students, academic staff and clinical staff about student experience of the transition to the first clinical placement. Results: In general, most students enjoyed their first clinical placement, and the opportunity to put theory into practice. However, three key themes emerged from the data that caused students difficulty in the first clinical placement; working with clinical staff, working with very ill patients, and moving around the department each week. Key Conclusions: This study has identified that some aspects of the transition into the first clinical placement need to be improved. Recommendations have been made for curriculum development in the academic block prior to the first clinical placement, and to improve student support during clinical placement. The implementation of these recommendations is crucial to reduce the dissonance between theory and practice, and improve student experience of the transition to the first clinical placement. - Highlights: • Issues for student radiographers during their first clinical placement are identified. • Recommendations made for curriculum development to improve preparation for clinical placement. • Recommendations made to improve student support in

  8. Optimal management of fatigue in patients with systemic lupus erythematosus: a systematic review

    Directory of Open Access Journals (Sweden)

    Yuen HK

    2014-10-01

    Full Text Available Hon K Yuen,1 Melissa A Cunningham2 1Department of Occupational Therapy, School of Health Professions, University of Alabama at Birmingham, Birmingham, AL, 2Division of Rheumatology and Immunology, Department of Medicine, Medical University of South Carolina, SC, USA Abstract: Among the host of distressing pathophysiological and psychosocial symptoms, fatigue is the most prevalent complaint in patients with systemic lupus erythematosus (SLE. This review is to update the current findings on non-pharmacological, pharmacological, and modality strategies to manage fatigue in patients with SLE and to provide some recommendations on optimal management of fatigue based on the best available evidence. We performed a systematic literature search of the PubMed and Scopus databases to identify publications on fatigue management in patients with SLE. Based on the studies reported in the literature, we identified nine intervention strategies that have the potential to alleviate fatigue in patients with SLE. Of the nine strategies, aerobic exercise and belimumab seem to have the strongest evidence of treatment efficacy. N-acetylcysteine and ultraviolet-A1 phototherapy demonstrated low-to-moderate levels of evidence. Psychosocial interventions, dietary manipulation (low calorie or glycemic index diet aiming for weight loss, vitamin D supplementation, and acupuncture all had weak evidence. Dehydroepiandrosterone is not recommended due to a lack of evidence for its efficacy. In addition to taking treatment efficacy and side effects into consideration, clinicians should consider factors such as cost of treatment, commitments, and burden to the patient when selecting fatigue management strategies for patients with SLE. Any comorbidities, such as psychological distress, chronic pain, sleep disturbance, obesity, or hypovitaminosis D, associated with fatigue should be addressed. Keywords: health-related quality of life, vitality, systemic lupus erythematosus, clinical

  9. Blue Ribbon Commission on America's Nuclear Future: Report to the Secretary of Energy

    Energy Technology Data Exchange (ETDEWEB)

    None

    2012-01-01

    Preamble The Blue Ribbon Commission on America’s Nuclear Future (BRC) was formed by the Secretary of Energy at the request of the President to conduct a comprehensive review of policies for managing the back end of the nuclear fuel cycle and recommend a new strategy. It was co-chaired by Rep. Lee H. Hamilton and Gen. Brent Scowcroft. Other Commissioners are Mr. Mark H. Ayers, the Hon. Vicky A. Bailey, Dr. Albert Carnesale, Sen. Pete Domenici, Ms. Susan Eisenhower, Sen. Chuck Hagel, Mr. Jonathan Lash, Dr. Allison M. Macfarlane, Dr. Richard A. Meserve, Dr. Ernest J. Moniz, Dr. Per Peterson, Mr. John Rowe, and Rep. Phil Sharp. The Commission and its subcommittees met more than two dozen times between March 2010 and January 2012 to hear testimony from experts and stakeholders, to visit nuclear waste management facilities in the United States and abroad, and to discuss the issues identified in its Charter. Additionally, in September and October 2011, the Commission held five public meetings, in different regions of the country, to hear feedback on its draft report. A wide variety of organizations, interest groups, and individuals provided input to the Commission at these meetings and through the submission of written materials. Copies of all of these submissions, along with records and transcripts of past meetings, are available at the BRC website (www.brc.gov). This report highlights the Commission’s findings and conclusions and presents recommendations for consideration by the Administration and Congress, as well as interested state, tribal and local governments, other stakeholders, and the public.

  10. Obstetrics at Decisive Crossroads Regarding Pattern-Recognition of Fetal Heart Rate Decelerations: Scientific Principles and Lessons From Memetics.

    Science.gov (United States)

    Sholapurkar, Shashikant L

    2018-04-01

    The survival of cardiotocography (CTG) as a tool for intrapartum fetal monitoring seems threatened somewhat unjustifiably and unwittingly despite the absence of better alternatives. Fetal heart rate (FHR) decelerations are center-stage (most important) in the interpretation of CTG with maximum impact on three-tier classification. The pattern-discrimination of FHR decelerations is inexorably linked to their nomenclature. Unscientific or flawed nomenclature of decelerations can explain the dysfunctional CTG interpretation leading to errors in detection of acidemic fetuses. There are three contrasting concepts about categorization of FHR decelerations: 1) all rapid decelerations (the vast majority) should be grouped as "variable" because they are predominantly due to cord-compression, 2) all decelerations are due to chemoreflex from fetal hypoxemia hence their timing is not important, and 3) FHR decelerations should be categorized into "early/late/variable" based primarily on their time relationship to contractions. These theoretical concepts are like memes (ideas/beliefs). Lessons from "memetics" are that the most popular, attractive or established beliefs may not necessarily be true, scientific, beneficial or even without harm. Decelerations coincident with contractions with trough corresponding to the peak of contractions cannot be explained by cord-compression or increasing hypoxia (from compromised uteroplacental perfusion, cord-compression or even cerebral hypoperfusion/anoxia purportedly conceivable from head-compression). Decelerations due to hypoxemia would be associated with delayed recovery of decelerations (lag phase). It is a scientific imperative to cast away disproven/falsified theories. Practices based on unscientific theories lead to patient harm. Clinicians should urgently adopt the categorization of FHR decelerations based primarily of the time relationship to contractions as originally proposed by Hon and Caldeyro-Barcia. This analytical review

  11. La planeación estratégica en las pymes colombianas: un aporte para empresas contratistas de la FAC

    Directory of Open Access Journals (Sweden)

    Rafael Pérez Uribe

    2014-01-01

    Full Text Available Las micro, pequeñas y medianas empresas (Mipymes, cumplen un papel primordial en el desarrollo económico de los países y Colombia no es la excepción: ellas sirven como tejido auxiliar de las grandes empresas, quienes contratan este tipo de compañías para la prestación de servicios que de estar incluidos en la producción general de las mismas implicarían un aumento de coste. Una de las definiciones de la planeación estratégica está relacionada con la fijación de objetivos y formulación de procedimientos y métodos para alcanzarlos. Para ello debe fijarse un direccionamiento, el cual repercute de forma directa en la consecución de ventajas competitivas que le permitirán a la compañía la perpetuidad en el mercado. Es así como, la dirección estratégica se consolida como pilar fundamental de este tipo de organizaciones, las cuales soportan en su gran mayoría la economía colombiana. El objetivo de este artículo es mostrar algunos conceptos relacionados con la importancia de la planeación y direccionamiento estratégico, y de igual forma mostrar aquellas variables que explican en mayor proporcionalidad la sostenibilidad de una organización en relación con el direccionamiento estratégico, a la luz Modelo de Modernización para la Gestión de Organizaciones (MMGO desarrollado por la Universidad EAN en Colombia.

  12. A conexão presidencial: facções pró e antigoverno e disciplina partidária no Brasil

    Directory of Open Access Journals (Sweden)

    Amorim Neto Octavio

    2001-01-01

    Full Text Available The article provides an explanation for the enormous variation in party discipline during the Brazilian democratic experience from 1946 to 1964. The argument is that party discipline is a function of the Presidents? strategies in forging coalitions in Congress. One of the main consequences of such strategies was the creation of two factions within parties, one for and the other against the President. The premise is that the size of each faction affects its level of discipline. According to an econometric analysis of 982 roll-call votes, crucial determinants of discipline in the larger parties were the amount of budget resources allocated to them by the President and the time remaining in the President?s term.

  13. Normal expression of the Fanconi anemia proteins FAA and FAC and sensitivity to mitomycin C in two patients with Seckel syndrome

    NARCIS (Netherlands)

    Abou-Zahr, F; Bejjani, B; Kruyt, FAE; Kurg, R; Bacino, C; Shapira, SK; Youssoufian, H

    1999-01-01

    Seckel syndrome is a rare autosomal recessive disorder. The classical presentation includes pre- and postnatal growth deficiency, mental retardation, and characteristic facial appearance. There have been several reports of associated hematological abnormalities and chromosomal breakage, findings

  14. Draft Title 40 CFR 191 compliance certification application for the Waste Isolation Pilot Plant. Volume 5: Appendices D and D, DEF, FAC

    International Nuclear Information System (INIS)

    1995-01-01

    This plan serves to describe the objectives of decommissioning for the Waste Isolation Pilot Plant (WIPP), identifies the elements necessary to accomplish the decommissioning, and defines the steps to execute those elements in a safe and environmentally sound manner. The plan provides a strategy for progressing from the final actions of the Disposal Phase, through the Decontamination and Decommissioning Phase, and into the initiation of the Long-Term Monitoring Phase. This plan describes a sequence of events for decontamination of the WIPP facilities and structures used to manage and contain TRU and TRU mixed waste during the receipt and emplacement operations. Alternative methods of decontamination are provided where practical. The methods for packaging and disposal of the waste generated (derived waste) during this process are discussed. The best available technology at the time of this plan's development, may become outmoded by future technology and alternative strategies. If alternative technologies are identified the affected stakeholder(s), the Secretary of the Interior and the State will be consulted prior to implementation

  15. THE MEANING OF THE PREVENTION WITH SPEECH THERAPY AS A IMPORTANT FAC-TOR FOR THE PROPER DEVELOPMENT OF THE CHILDREN SPEECH

    Directory of Open Access Journals (Sweden)

    S. FILIPOVA

    1999-11-01

    Full Text Available The paper presented some conscientious and results from the finished research which showing the meaning of the prevention with speech therapy in the development of the speech. The research was done at Negotino and with that are shown the most frequent speech deficiency of the children at preschool age.

  16. Probing the mer- to fac-isomerization of tris-cyclometallated homo- and heteroleptic (C,N)3 Iridium(III) complexes

    NARCIS (Netherlands)

    McDonald, A.R.; Lutz, M.; von Chrzanowski, L.S.; van Klink, G.P.M.; Spek, A.L.; van Koten, G.

    2008-01-01

    We have developed techniques which allow for covalent tethering, via a “hetero” cyclometallating ligand, of heteroleptic tris-cyclometallated iridium(III) complexes to polymeric supports (for application in light-emitting diode technologies). This involved the selective synthesis and thorough

  17. 3,6-Bis(2-pyrazinyl)-1,2,4,5-tetrazin: Ein neuer mehrfunktioneller Ligand und sein syn,fac-konfigurierter Bis(tricarbonylchlororhenium)-Komplex

    Czech Academy of Sciences Publication Activity Database

    Sarkar, B.; Kaim, W.; Schleid, T.; Hartenbach, I.; Fiedler, Jan

    2003-01-01

    Roč. 629, - (2003), s. 1353-1357 ISSN 0044-2313 R&D Projects: GA MŠk OC D14.20; GA MŠk OC D15.10 Institutional research plan: CEZ:AV0Z4040901 Keywords : carbonyl ligands * heterocyclic ligands * rhenium Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 1.127, year: 2003

  18. Draft Title 40 CFR 191 compliance certification application for the Waste Isolation Pilot Plant. Volume 5: Appendices D and D, DEF, FAC

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-03-31

    This plan serves to describe the objectives of decommissioning for the Waste Isolation Pilot Plant (WIPP), identifies the elements necessary to accomplish the decommissioning, and defines the steps to execute those elements in a safe and environmentally sound manner. The plan provides a strategy for progressing from the final actions of the Disposal Phase, through the Decontamination and Decommissioning Phase, and into the initiation of the Long-Term Monitoring Phase. This plan describes a sequence of events for decontamination of the WIPP facilities and structures used to manage and contain TRU and TRU mixed waste during the receipt and emplacement operations. Alternative methods of decontamination are provided where practical. The methods for packaging and disposal of the waste generated (derived waste) during this process are discussed. The best available technology at the time of this plan`s development, may become outmoded by future technology and alternative strategies. If alternative technologies are identified the affected stakeholder(s), the Secretary of the Interior and the State will be consulted prior to implementation.

  19. Follow-on to a report on the Applicability of the “Gallet equation” to the vegetation clearances of NERC Reliability Standard FAC-003-2

    Energy Technology Data Exchange (ETDEWEB)

    Kirkham, Harold

    2012-08-31

    In earlier work, a study done at the Pacific Northwest National Laboratory examined a NERC proposed standard specifying clearances between vegetation and power lines. The method proposed for calculating the clearances was based on the results of testing for high-voltage line designs. An equation developed to relate the results of testing with rod-plane gaps to proposed tower window sizes was incorporated into the calculations. The equation in question, sometimes called the “Gallet equation,” describes the insulation performance of the atmosphere for air gaps of a few meters. The equation was described in the PNNL study as a good and simple-to-use way to solve a problem made difficult by the nonlinear interactions of the variables. For calculations based on this equation, a certain set of assumptions must be made. In particular, a value for a quantity called the “gap factor” is needed. This is the amount by which the gap to be modeled by the equation is stronger than the reference gap that was used in developing the Gallet equation. That reference gap is the gap between a rod and a plane. This follow-on report examines the effect on flashover probabilities of assuming an incorrect value for the gap factor. In particular, the flashover probability is found that would result from using a value of 1.3 when a gap factor of 1.0 should be applied. It is shown that with these assumptions the probability of a flashover changes from being extremely unlikely (about 1 in 1000 chance) to a virtual certainty (about 97% chance).

  20. PREFACE: International Conference on Inverse Problems 2010

    Science.gov (United States)

    Hon, Yiu-Chung; Ling, Leevan

    2011-03-01

    Following the first International Conference on Inverse Problems - Recent Theoretical Development and Numerical Approaches held at the City University of Hong Kong in 2002, the fifth International Conference was held again at the City University during December 13-17, 2010. This fifth conference was jointly organized by Professor Yiu-Chung Hon (Co-Chair, City University of Hong Kong, HKSAR), Dr Leevan Ling (Co-Chair, Hong Kong Baptist University, HKSAR), Professor Jin Cheng (Fudan University, China), Professor June-Yub Lee (Ewha Womans University, South Korea), Professor Gui-Rong Liu (University of Cincinnati, USA), Professor Jenn-Nan Wang (National Taiwan University, Taiwan), and Professor Masahiro Yamamoto (The University of Tokyo, Japan). It was agreed to alternate holding the conference among the above places (China, Japan, Korea, Taiwan, and Hong Kong) once every two years. The next conference has been scheduled to be held at the Southeast University (Nanjing, China) in 2012. The purpose of this series of conferences is to establish a strong collaborative link among the universities of the Asian-Pacific regions and worldwide leading researchers in inverse problems. The conference addressed both theoretical (mathematics), applied (engineering) and developmental aspects of inverse problems. The conference was intended to nurture Asian-American-European collaborations in the evolving interdisciplinary areas and it was envisioned that the conference would lead to long-term commitments and collaborations among the participating countries and researchers. There was a total of more than 100 participants. A call for the submission of papers was sent out after the conference, and a total of 19 papers were finally accepted for publication in this proceedings. The papers included in the proceedings cover a wide scope, which reflects the current flourishing theoretical and numerical research into inverse problems. Finally, as the co-chairs of the Inverse Problems

  1. The need to enhance the employability competences (knowledge, skills, autonomy, and attitudes of undergraduates in Agriculture. Evidence from students’ perceptions and employers’ expectations

    Directory of Open Access Journals (Sweden)

    Nigel Yoven Armoogum

    2016-11-01

    , proposed for the degree of BSc (Hons Agriscience and Technology of the FoA.[1] “Digest of Agricultural Statistics Mauritius,” Ministry of Finance and Economic Development, http://statsmauritius.govmu.org/English/StatsbySubj/Documents/Digest/Digest%20of%20Agricultural%20Statistics%202014.pdf.

  2. 從家課的質與量看香港課程改革的實施 The Quality and Quantity of Homework in Hong Kong Primary Schools: An Indicator of Curriculum Reform Implementation

    OpenAIRE

    林智中 Chi-Chung Lam; 鄧詠之(通訊作者)Blanche Wing-Zhi Tang (Corresponding Author)

    2014-01-01

    華人地區深受傳統儒家文化影響,不少家長及教師都認同「勤有功、戲無益」、「有志者、事竟成」和「鐵柱磨成針」等傳統觀念。因此長期以來,香港學童都面對家課量多、家課深、長時間做家課的問題。2001年,香港特區政府推行教育改革,建議學校適當編排學生家課的數量,從而提升教與學的質素。為求了解香港學童家課的質與量是否因家課政策的實施而得以改善,本研究在香港10所小學進行調查,邀請各所學校其中一班五年級學生填寫問卷,統計完成家課的時間和家課類型,並訪問教師了解他們在家課設計、家課類型、家課功能等方面的考量。研究顯示,相對於課程改革之前,學生每天花在家課的時間的確減少;然而,大部分家課仍是紙筆練習,以鞏固課堂所學為主,較少有發展性的家課。分析這些研究結果背後的成因,有助於了解香港課程改革實施的狀況。Parents and teachers across Chinese societies mostly uphold the traditional belief of Confucianism that “hard work is the key to success.” As such, Hon...

  3. Critical Imperative for the Reform of British Interpretation of Fetal Heart Rate Decelerations: Analysis of FIGO and NICE Guidelines, Post-Truth Foundations, Cognitive Fallacies, Myths and Occam's Razor.

    Science.gov (United States)

    Sholapurkar, Shashikant L

    2017-04-01

    false premise to begin with. This is not surprising considering that the commonest pathophysiology of intrapartum hypoxemia is contraction-induced reduction in uteroplacental perfusion (sometimes already compromised) and not cord compression at all. This distorted categorization causes confusion, false-alarm fatigue and difficulty in focusing on real pathological decelerations making CTG interpretation dysfunctional ultimately compromising patient safety. Obstetricians/midwives should demand reverting to the previous more scientific British categorization of decelerations based solely on time relationship to contractions as advocated by the pioneers like Hon and Caldeyro-Barcia, rather than accepting the current "post-truth" scenario.

  4. Critical Imperative for the Reform of British Interpretation of Fetal Heart Rate Decelerations: Analysis of FIGO and NICE Guidelines, Post-Truth Foundations, Cognitive Fallacies, Myths and Occam’s Razor

    Science.gov (United States)

    Sholapurkar, Shashikant L.

    2017-01-01

    unresolved suggesting a false premise to begin with. This is not surprising considering that the commonest pathophysiology of intrapartum hypoxemia is contraction-induced reduction in uteroplacental perfusion (sometimes already compromised) and not cord compression at all. This distorted categorization causes confusion, false-alarm fatigue and difficulty in focusing on real pathological decelerations making CTG interpretation dysfunctional ultimately compromising patient safety. Obstetricians/midwives should demand reverting to the previous more scientific British categorization of decelerations based solely on time relationship to contractions as advocated by the pioneers like Hon and Caldeyro-Barcia, rather than accepting the current “post-truth” scenario. PMID:28270884

  5. Symbolic computation of analytic approximate solutions for nonlinear fractional differential equations

    Science.gov (United States)

    Lin, Yezhi; Liu, Yinping; Li, Zhibin

    2013-01-01

    é approximants technique, a new algorithm is proposed to construct analytic approximate solutions for nonlinear fractional differential equations. Restrictions: The problem [2] with some Robin boundary conditions can not be solved by this program. Running time: Seconds at most in routine uses of the program. Special tasks may take up to some minutes. References: [1] Rach, R., Kybernetes 37 (2008) 910. [2] Hon, YC., Southeast Asian Bulletin of Mathematics 3 (1996) 55.

  6. Characterizing the Aedes aegypti Population in a Vietnamese Village in Preparation for a Wolbachia-Based Mosquito Control Strategy to Eliminate Dengue

    Science.gov (United States)

    Jeffery, Jason A. L.; Thi Yen, Nguyen; Nam, Vu Sinh; Nghia, Le Trung; Hoffmann, Ary A.; Kay, Brian H.; Ryan, Peter A.

    2009-01-01

    Background A life-shortening strain of the obligate intracellular bacteria Wolbachia, called wMelPop, is seen as a promising new tool for the control of Aedes aegypti. However, developing a vector control strategy based on the release of mosquitoes transinfected with wMelPop requires detailed knowledge of the demographics of the target population. Methodology/Principal Findings In Tri Nguyen village (611 households) on Hon Mieu Island in central Vietnam, we conducted nine quantitative entomologic surveys over 14 months to determine if Ae. aegypti populations were spatially and temporally homogenous, and to estimate population size. There was no obvious relationship between mosquito (larval, pupal or adult) abundance and temperature and rainfall, and no area of the village supported consistently high numbers of mosquitoes. In almost all surveys, key premises produced high numbers of Ae. aegypti. However, these premises were not consistent between surveys. For an intervention based on a single release of wMelPop-infected Ae. aegypti, release ratios of infected to uninfected adult mosquitoes of all age classes are estimated to be 1.8–6.7∶1 for gravid females (and similarly aged males) or teneral adults, respectively. We calculated that adult female mosquito abundance in Tri Nguyen village could range from 1.1 to 43.3 individuals of all age classes per house. Thus, an intervention could require the release of 2–78 wMelPop-infected gravid females and similarly aged males per house, or 7–290 infected teneral female and male mosquitoes per house. Conclusions/Significance Given the variability we encountered, this study highlights the importance of multiple entomologic surveys when evaluating the spatial structure of a vector population or estimating population size. If a single release of wMelPop-infected Ae. aegypti were to occur when wild Ae. aegypti abundance was at its maximum, a preintervention control program would be necessary to ensure that there was no

  7. Characterizing the Aedes aegypti population in a Vietnamese village in preparation for a Wolbachia-based mosquito control strategy to eliminate dengue.

    Directory of Open Access Journals (Sweden)

    Jason A L Jeffery

    Full Text Available BACKGROUND: A life-shortening strain of the obligate intracellular bacteria Wolbachia, called wMelPop, is seen as a promising new tool for the control of Aedes aegypti. However, developing a vector control strategy based on the release of mosquitoes transinfected with wMelPop requires detailed knowledge of the demographics of the target population. METHODOLOGY/PRINCIPAL FINDINGS: In Tri Nguyen village (611 households on Hon Mieu Island in central Vietnam, we conducted nine quantitative entomologic surveys over 14 months to determine if Ae. aegypti populations were spatially and temporally homogenous, and to estimate population size. There was no obvious relationship between mosquito (larval, pupal or adult abundance and temperature and rainfall, and no area of the village supported consistently high numbers of mosquitoes. In almost all surveys, key premises produced high numbers of Ae. aegypti. However, these premises were not consistent between surveys. For an intervention based on a single release of wMelPop-infected Ae. aegypti, release ratios of infected to uninfected adult mosquitoes of all age classes are estimated to be 1.8-6.7ratio1 for gravid females (and similarly aged males or teneral adults, respectively. We calculated that adult female mosquito abundance in Tri Nguyen village could range from 1.1 to 43.3 individuals of all age classes per house. Thus, an intervention could require the release of 2-78 wMelPop-infected gravid females and similarly aged males per house, or 7-290 infected teneral female and male mosquitoes per house. CONCLUSIONS/SIGNIFICANCE: Given the variability we encountered, this study highlights the importance of multiple entomologic surveys when evaluating the spatial structure of a vector population or estimating population size. If a single release of wMelPop-infected Ae. aegypti were to occur when wild Ae. aegypti abundance was at its maximum, a preintervention control program would be necessary to ensure that

  8. Experiences in teaching decommissioning - 16179

    International Nuclear Information System (INIS)

    Catlow, Fred

    2009-01-01

    examination papers prepared which were validated by internal and external assessors. The first course was started in 2004 (believed to be unique at that time) and attracted eight students. Subsequent courses have been promoted as well as a BEng (Hons) course which also included a course on Safety and Reliability. (authors)

  9. Cathelicidin suppresses colon cancer development by inhibition of cancer associated fibroblasts

    Directory of Open Access Journals (Sweden)

    Cheng M

    2014-12-01

    Full Text Available Michelle Cheng,1,* Samantha Ho,1,* Jun Hwan Yoo,1,2,* Deanna Hoang-Yen Tran,1,* Kyriaki Bakirtzi,1 Bowei Su,1 Diana Hoang-Ngoc Tran,1 Yuzu Kubota,1 Ryan Ichikawa,1 Hon Wai Koon1 1Center for Inflammatory Bowel Diseases, Division of Digestive Diseases, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA; 2Digestive Disease Center, CHA University Bundang Medical Center, Seongnam, Republic of Korea *These authors share co-first authorship Background: Cathelicidin (LL-37 in humans and mCRAMP in mice represents a family of endogenous antimicrobial and anti-inflammatory peptides. Cancer-associated fibroblasts can promote the proliferation of colon cancer cells and growth of colon cancer tumors. Methods: We examined the role of cathelicidin in the development of colon cancer, using subcutaneous human HT-29 colon-cancer-cell-derived tumor model in nude mice and azoxymethane- and dextran sulfate-mediated colon cancer model in C57BL/6 mice. We also determined the indirect antitumoral mechanism of cathelicidin via the inhibition of epithelial–mesenchymal transition (EMT of colon cancer cells and fibroblast-supported colon cancer cell proliferation. Results: Intravenous administration of cathelicidin expressing adeno-associated virus significantly reduced the size of tumors, tumor-derived collagen expression, and tumor-derived fibroblast expression in HT-29-derived subcutaneous tumors in nude mice. Enema administration of the mouse cathelicidin peptide significantly reduced the size and number of colonic tumors in azoxymethane- and dextran sulfate-treated mice without inducing apoptosis in tumors and the adjacent normal colonic tissues. Cathelicidin inhibited the collagen expression and vimentin-positive fibroblast expression in colonic tumors. Cathelicidin did not directly affect HT-29 cell viability, but did significantly reduce tumor growth factor-ß1-induced EMT of colon cancer cells. Media conditioned by the

  10. Global atmospheric dispersion modelling after the Fukushima accident

    Energy Technology Data Exchange (ETDEWEB)

    Suh, K.S.; Youm, M.K.; Lee, B.G.; Min, B.I. [Korea Atomic Energy Research Institute (Korea, Republic of); Raul, P. [Universidad de Sevilla (Spain)

    2014-07-01

    A large amount of radioactive material was released to the atmosphere due to the Fukushima nuclear accident in March 2011. The radioactive materials released into the atmosphere were mostly transported to the Pacific Ocean, but some of them were fallen on the surface due to dry and wet depositions in the northwest area from the Fukushima nuclear site. Therefore, northwest part of the nuclear site was seriously contaminated and it was designated with the restricted zone within a radius of 20 ∼ 30 km around the Fukushima nuclear site. In the early phase of the accident from 11 March to 30 March, the radioactive materials were dispersed to an area of the inland and offshore of the nuclear site by the variations of the wind. After the Fukushima accident, the radionuclides were detected through the air monitoring in the many places over the world. The radioactive plume was transported to the east part off the site by the westerly jet stream. It had detected in the North America during March 17-21, in European countries during March 23-24, and in Asia during from March 24 to April 6, 2011. The radioactive materials were overall detected across the northern hemisphere passed by 15 ∼ 20 days after the accident. Three dimensional numerical model was applied to evaluate the dispersion characteristics of the radionuclides released into the air. Simulated results were compared with measurements in many places over the world. Comparative results had good agreements in some places, but they had a little differences in some locations. The difference between the calculations and measurements are due to the meteorological data and relatively coarse resolutions in the model. Some radioactive materials were measured in Philippines, Taiwan, Hon Kong and South Korea during from March 23-28. It inferred that it was directly transported from the Fukushima by the northeastern monsoon winds. This event was well represented in the numerical model. Generally, the simulations had a good

  11. Nitrite-reductase and peroxynitrite isomerization activities of Methanosarcina acetivorans protoglobin.

    Directory of Open Access Journals (Sweden)

    Paolo Ascenzi

    Full Text Available Within the globin superfamily, protoglobins (Pgb belong phylogenetically to the same cluster of two-domain globin-coupled sensors and single-domain sensor globins. Multiple functional roles have been postulated for Methanosarcina acetivorans Pgb (Ma-Pgb, since the detoxification of reactive nitrogen and oxygen species might co-exist with enzymatic activity(ies to facilitate the conversion of CO to methane. Here, the nitrite-reductase and peroxynitrite isomerization activities of the CysE20Ser mutant of Ma-Pgb (Ma-Pgb* are reported and analyzed in parallel with those of related heme-proteins. Kinetics of nitrite-reductase activity of ferrous Ma-Pgb* (Ma-Pgb*-Fe(II is biphasic and values of the second-order rate constant for the reduction of NO2- to NO and the concomitant formation of nitrosylated Ma-Pgb*-Fe(II (Ma-Pgb*-Fe(II-NO are k(app1= 9.6 ± 0.2 M(-1 s(-1 and k(app2 = 1.2 ± 0.1 M(-1 s(-1 (at pH 7.4 and 20 °C. The k(app1 and k(app2 values increase by about one order of magnitude for each pH unit decrease, between pH 8.3 and 6.2, indicating that the reaction requires one proton. On the other hand, kinetics of peroxynitrite isomerization catalyzed by ferric Ma-Pgb* (Ma-Pgb*-Fe(III is monophasic and values of the second order rate constant for peroxynitrite isomerization by Ma-Pgb*-Fe(III and of the first order rate constant for the spontaneous conversion of peroxynitrite to nitrate are h(app = 3.8 × 10(4 M(-1 s(-1 and h0 = 2.8 × 10(-1 s(-1 (at pH 7.4 and 20 °C. The pH-dependence of hon and h0 values reflects the acid-base equilibrium of peroxynitrite (pKa = 6.7 and 6.9, respectively; at 20 °C, indicating that HOONO is the species that reacts preferentially with the heme-Fe(III atom. These results highlight the potential role of Pgbs in the biosynthesis and scavenging of reactive nitrogen and oxygen species.

  12. Automated Detection of HONcode Website Conformity Compared to Manual Detection: An Evaluation.

    Science.gov (United States)

    Boyer, Célia; Dolamic, Ljiljana

    2015-06-02

    To earn HONcode certification, a website must conform to the 8 principles of the HONcode of Conduct In the current manual process of certification, a HONcode expert assesses the candidate website using precise guidelines for each principle. In the scope of the European project KHRESMOI, the Health on the Net (HON) Foundation has developed an automated system to assist in detecting a website's HONcode conformity. Automated assistance in conducting HONcode reviews can expedite the current time-consuming tasks of HONcode certification and ongoing surveillance. Additionally, an automated tool used as a plugin to a general search engine might help to detect health websites that respect HONcode principles but have not yet been certified. The goal of this study was to determine whether the automated system is capable of performing as good as human experts for the task of identifying HONcode principles on health websites. Using manual evaluation by HONcode senior experts as a baseline, this study compared the capability of the automated HONcode detection system to that of the HONcode senior experts. A set of 27 health-related websites were manually assessed for compliance to each of the 8 HONcode principles by senior HONcode experts. The same set of websites were processed by the automated system for HONcode compliance detection based on supervised machine learning. The results obtained by these two methods were then compared. For the privacy criterion, the automated system obtained the same results as the human expert for 17 of 27 sites (14 true positives and 3 true negatives) without noise (0 false positives). The remaining 10 false negative instances for the privacy criterion represented tolerable behavior because it is important that all automatically detected principle conformities are accurate (ie, specificity [100%] is preferred over sensitivity [58%] for the privacy criterion). In addition, the automated system had precision of at least 75%, with a recall of more

  13. Un tributo a Roberto Caldeyro-Barcia, considerado el pionero de la Perinatología

    Directory of Open Access Journals (Sweden)

    A. Zárate

    2017-03-01

    Full Text Available Roberto Caldeyro-Barcia nació en Montevideo en 1921, estudió Medicina graduándose como médico cirujano en 1947. Fue aceptado como investigador asociado en el Instituto de Fisiología bajo la supervisión del profesor Hermógenes Álvarez, quien estaba trabajando sobre el efecto de la actividad uterina en el pulso cardiaco fetal durante el parto. La presión amniótica se registró con el uso de un pequeño catéter introducido dentro de la cavidad amniótica, por lo que Caldeyro-Barcia propuso introducir un microcatéter directamente en el músculo uterino para obtener información más específica de la contracción uterina y su efecto sobre la actividad cardiaca fetal. Se observó que la frecuencia cardiaca disminuía en los casos de hipoxia fetal. Dichos descensos fueron llamados DIP I y II. Así, se confirmó que la hipoxia durante el parto tiene una deletérea acción en la oxigenación fetal, lo cual fue registrado y graduado como unidades montevideo. Dos años después, Edward H. Hon, quien trabajaba en la Universidad de Yale, confirmó estos hallazgos, lo que fue el inicio de la monitorización fetal durante el trabajo de parto en todo el mundo. Caldeyro-Barcia fue galardonado por muchas asociaciones académicas internacionales; asimismo fue designado director del Centro Sudamericano de Perinatología y presidente de la Federación Internacional de Ginecología y Obstetricia. Se consideró un amigo de México, país que visitó muchas veces, por lo que tuvo una relación académica muy cercana con Luis Castelazo-Ayala.

  14. Strategies for resource management to improve agricultural productivity in Bariarpur Tal area of Bihar (India)

    International Nuclear Information System (INIS)

    Khan, A.R.; Upadhyaya, A.; Bhatnagar, P.R.; Gautam, U.S.; Singh, S.K.; Singh, S.R.

    2002-06-01

    Water logged Tal area is termed as the stretch of land having bowl shaped depressions inundated in monsoon season due to spill/overflow from rivers or runoff from upstream end. A team of Agricultural Scientists studied and suggested a suitable plan to the Ministry of Agriculture, Government of India for improving the agricultural productivity of 40,000 hectares land lying between Ghoraghat and Bariarpur and Prasando to Khand Bihari in Munger district of Bihar, which lies in eastern India. These lands remain inundated with water from July till January. Tal lands in Bariarpur suffer due to stagnation of water during monsoon period and delay in drainage thereafter. This is a late winter mono-cropped area with very low productivity. Though the fertility status of soil is good, the quantity and quality of produce is poor. The canal network is also not efficient and other parts face drought. It is expected that the Ministry of Agriculture, Government of India will take up the action plan as per the recommendations of expert scientists' team to mitigate the sufferings and misery of the farmers and rural population of the area. The team of scientists had investigated in detail the genesis of the problem and suggested the appropriate management strategies to improve the agricultural production in this area upon the instruction of the Hon'ble Union Agricultural Minister Mr. Nitish Kumar. A reputed Journalist and dedicated Social Worker Mr. Dinesh brought the unbelievable misery of the rural population to the attention of the Agricultural Minister. The sufferings of the farmers of Bariarpur tal area thus cannot be mitigated without the implementation of recommendations suggested in the scientific report. It seems that a financial crunch is coming in the way for such implementation. Ministry of Agriculture, Ministry of Water Resources, State Government, NGOs and Social Organizations should come forward to help the rural population otherwise the ray of hope for a better living

  15. Bad news. Analysis of the quality of information on influenza prevention returned by Google in English and Italian.

    Directory of Open Access Journals (Sweden)

    Ali eMaki

    2015-12-01

    Full Text Available Information available to the public influences the approach of the population towards vaccination against influenza compared with other preventative approaches. In this study we have analyzed the first 200 websites returned by searching Google on two topics (prevention of influenza and influenza vaccine, in English and Italian. For all the four searches above, websites were classified according to their typology (government, commercial, professional, portals etc. and for their trustworthiness as defined by the Journal of the American Medical Association (JAMA score which assesses whether they provide some basic elements of information quality (IQ: authorship, currency, disclosure and references. The type of information described was also assessed to add another dimension of IQ. Websites on influenza prevention were classified according to the type of preventative approach mentioned (vaccine, lifestyle, hygiene, complementary medicine etc., whether the approaches were in agreement with evidence based medicine (EBM or not. Websites on influenza vaccination were classified as pro- or anti-vaccine, or neutral. The great majority of websites described EBM approaches to influenza prevention and had a pro-vaccine orientation. Government websites mainly pointed at EBM preventative approaches and had a pro-vaccine orientation, while there was a higher proportion of commercial websites among those which promote non-EBM approaches. Although the JAMA score was lower in commercial websites, it did not correlate with the preventative approaches suggested or the orientation toward vaccines. For each of the four search engine result pages (SERP, only one website displayed the health-of-the-net (HON seal.In the SERP on vaccines, journalistic websites were the most abundant category and ranked higher than average in both languages. Analysis using natural language processing showed that journalistic websites were mostly reporting news about two specific topics

  16. Injured workers’ perception of loss and gain in the return to work process

    Directory of Open Access Journals (Sweden)

    Lai HS

    2017-02-01

    Full Text Available Hon Sun Lai,1,2 Grace PY Szeto,1 Chetwyn CH Chan3 1Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, 2Total Rehabilitation Management (Hong Kong Limited, 3Applied Cognitive Neuroscience Laboratory, Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong Abstract: When a worker is injured at work, he has to face a tough decision-making process about when and how to return to work (RTW. This study tests how the prospect theory can be applied to influence the injured workers’ perceptions about this important choice. One hundred forty-one injured workers were presented with wage- and pain-related information in four different message framing (negatively or positively and precision (smaller or larger number conditions. After exposure to the specific combination of this wage and pain information, the participants were asked to express intentions to RTW in terms of perceived chance, confidence, and anticipated sick leave duration. When asked to predict their RTW outcome, 101 participants (72.3% responded favorably, whereas only 40 (27.7% indicated an expectation for staying on sick leave. The present results did not show significant differences in the participants’ responses to the positively and negatively framed information about wage and pain. However, it was noted that the control group that was presented with positive framing for both “wage” and “pain” information showed higher scores in expectation and confidence for RTW, whereas the Ambivalent Group that had both negative messages showed lower scores. Seventy-nine participants who had ≥60% perceived improvement in condition were selected for further analysis, and those who were presented with “wage loss” information rated significantly higher perceived chance of RTW than those in the “pain gain” group. More in-depth investigation is warranted on this topic, with a larger sample of injured workers to investigate the

  17. Na Bahia Setecentista, um pioneiro do abolicionismo? In eighteenth-century Bahia, a pioneer of abolitionism?

    Directory of Open Access Journals (Sweden)

    OFM Fr. Hugo Fragoso

    2012-12-01

    Full Text Available No ano de 1992, foi republicado por Paulo Suess Etíope Resgatado, de autoria do Pe. Manuel Ribeiro Rocha. Tratava-se de obra raríssima, pois, quanto consta, só havia em todo o Brasil um único exemplar, na Biblioteca Nacional do Rio de Janeiro. Já vinha eu fazendo pesquisas em torno do Pe. Ribeiro Rocha, a quem costumava qualificar de "pioneiro do abolicionismo" no Brasil. Com a reedição de Etíope Resgatado, tomei conhecimento da leitura de Paulo Suess, numa direção quase totalmente contrária. Para este, Ribeiro Rocha não passaria de um simples "reformista", que nada acrescentara de ideia libertária ao problema da escravidão negra. Aliás, essa tinha sido a tese de Ronaldo Vainfas e José Honório Rodrigues, que veem na obra de Ribeiro Rocha mais um exemplar do "pensamento escravista", que apenas condenava, como o faziam todos os homens de Igreja, os excessos e barbaridades da escravidão negra. Todo este nosso trabalho se orienta, portanto, na direção de uma leitura "abolicionista" do Etíope Resgatado, embora admita as evidências claras de "concessões" feitas por Ribeiro Rocha à situação escravocrata de seu tempo.In 1992, there was republished by Paulo Suess "Etíope resgatado", written by Father Manuel Ribeiro Rocha. It was very rare work, because, as stated, there was a single copy in the National Library of Rio de Janeiro in Brazil. I had, at this point, already started a research about the Father Ribeiro Rocha, whom used to be described as "a pioneer of abolitionism" in Brazil. With the reissue of "Etíope resgatado", I took notice about Paulo Suess lecture, in an almost completely opposite direction. According to Suess, Ribeiro Rocha was nothing more than a simple "reformer" who had added nothing to the problem of libertarian idea of black slavery. Incidentally, this was the thesis Vainfas Ronaldo and Jose Honorio Rodrigues argued, who saw the work of Ribeiro Rocha another copy of "slavery thought" which only condemned

  18. 77 FR 3751 - Commission Information Collection Activities (FERC-725A); Comment Request; Submitted for OMB Review

    Science.gov (United States)

    2012-01-25

    ... Commission, 888 First Street NE., Washington, DC 20426. FOR FURTHER INFORMATION CONTACT: Ellen Brown may be... Additional recordkeeping beyond FAC-008-1 FAC-008-3 Applies to: and FAC-009-1 and FAC-009-1 R1 Generator... Generator owners None, this requirement is derived Retention period increased by 2 years. from R1 of FAC-008...

  19. The relationship of thermospheric density anomaly with electron temperature, small-scale FAC, and ion up-flow in the cusp region, as observed by CHAMP and DMSP satellites

    Directory of Open Access Journals (Sweden)

    G. N. Kervalishvili

    2013-03-01

    Full Text Available We present in a statistical study a comparison of thermospheric mass density enhancements (ρrel with electron temperature (Te, small-scale field-aligned currents (SSFACs, and vertical ion velocity (Vz at high latitudes around noon magnetic local time (MLT. Satellite data from CHAMP (CHAllenging Minisatellite Payload and DMSP (Defense Meteorological Satellite Program sampling the Northern Hemisphere during the years 2002–2005 are used. In a first step we investigate the distribution of the measured quantities in a magnetic latitude (MLat versus MLT frame. All considered variables exhibit prominent peak amplitudes in the cusp region. A superposed epoch analysis was performed to examine causal relationship between the quantities. The occurrence of a thermospheric relative mass density anomaly, ρrel >1.2, in the cusp region is defining an event. The location of the density peak is taken as a reference latitude (Δ MLat = 0°. Interestingly, all the considered quantities, SSFACs, Te, and Vz are co-located with the density anomaly. The amplitudes of the peaks exhibit different characters of seasonal variation. The average relative density enhancement of the more prominent density peaks considered in this study amounts to 1.33 during all seasons. As expected, SSFACs are largest in summer with average amplitudes equal to 2.56 μA m−2, decaying to 2.00 μA m−2 in winter. The event related enhancements of Te and Vz are both largest in winter (Δ Te =730 K, Vz =136 m s−1 and smallest in summer (Δ Te = 377 K, Vz = 57 m s−1. Based on the similarity of the seasonal behaviour we suggest a close relationship between these two quantities. A correlation analysis supports a linear relation with a high coefficient greater than or equal to 0.93, irrespective of season. Our preferred explanation is that dayside reconnection fuels Joule heating of the thermosphere causing air upwelling and at the same time heating of the electron gas that pulls up ions along affected flux tubes.

  20. Recombinant coagulation factor VIIa labelled with the fac-99 mTc(CO)3-core: synthesis and in vitro evaluation of a putative new radiopharmaceutical for imaging in acute bleeding lesion

    DEFF Research Database (Denmark)

    Madsen, Jacob; Christensen, Jesper B.; Olsen, Ole H.

    2011-01-01

    Coagulation in blood is initiated when coagulation factor VII (FVII) binds to exposed TF and is activated to FVIIa, and the TF/ FVIIa complex may therefore provide a marker of vascular injury potentially applicable in diagnostic imaging of acute gastrointestinal (GI) bleeding. Methods: Recombinant...... yield and in 495% radiochemical purity. Pull down experiments showed that the biological activity (binding to tissue factor and to anti-FVII antibody) of the radiolabelled product remained intact in the formulation mixture as well as in human serum. By computer modeling analysis, two candidate sites...

  1. Fradejas Lebrero, José (ed.. Felipe V: Don Quijote. Tomo V. Madrid: CSIC ž Instituto de estudios madrileños; 39 pp. + facsímil ([4] + 58 pp.

    Directory of Open Access Journals (Sweden)

    Julia María Labrador Ben

    2006-12-01

    Full Text Available Sin duda, una de las publicaciones más originales aparecida con motivo del IV centenario de la publicación de El Quijote es el libro que ahora reseñamos. Continuaciones de obra tan famosa hubo más, indiscutiblemente de mayor calidad e interés literario, pero ésta resulta importante por su autor: nada menos que nuestro rey Felipe V, quien la escribió siendo todavía príncipe, cuando tan sólo contaba unos diez años según indica el manuscrito (año 1693, catorce o quince a lo sumo según las apreciaciones del profesor José Fradejas Lebrero, encargado de esta edición y gran especialista en la Edad Media y sobre todo en el Siglo de Oro, además de madrileñista y zamoranista insigne.

  2. Crystal structure of fac-[2-(4-methyl-5-phenylpyridin-2-ylphenyl-κ2C1,N]bis[2-(pyridin-2-ylphenyl-κ2C1,N]iridium(III

    Directory of Open Access Journals (Sweden)

    Chi-Heon Lee

    2016-12-01

    Full Text Available In the title compound, [Ir(C11H8N2(C18H14N], the IrIII ion adopts a distorted octahedral coordination environment defined by three C,N-chelating ligands, one stemming from a 2-(4-phenyl-5-methylpyridin-2-ylphenyl ligand and two from 2-(pyridin-2-ylphenyl ligands, arranged in a facial manner. The IrIII ion lies almost in the equatorial plane [deviation = 0.0069 (15 Å]. In the crystal, intermolecular π–π stacking interactions, as well as intermolecular C—H...π interactions, are present, leading to a three-dimensional network.

  3. 76 FR 17347 - Aviation Communications

    Science.gov (United States)

    2011-03-29

    ..., Emergency and distress. FAC, FAM. * * * * * * * 121.975 MHz F, S MA2, FAW, FAC, MOU..... Air traffic control operations. * * * * * * * 122.025 MHz F, S MA2, FAW, FAC, MOU..... Air traffic control operations. * * * * * * * 122.075 MHz F, S MA2, FAW, FAC, MOU..... Air traffic control operations. * * * * * * * 123.6-128.8 MHz...

  4. Guest Foreword by Lord Phillips KG PC

    Directory of Open Access Journals (Sweden)

    Nicholas A. Phillips

    2012-04-01

    Full Text Available The Rt Hon The Lord Phillips of Worth Matravers KG PC, President of the Supreme Court of the United Kingdom of Great Britain and Northern Ireland Ambition and excellence. Those two words epitomize Qatar. Under the leadership of his Highness the Emir, this small State has set out to make an impact on the world that belies its size. Ambitious was the plan to have an international broadcasting station. Ambitious was the plan to build from scratch a Museum of Islamic Art. Ambitious was the bid – the successful bid to host the World Cup in 2022. Ambitious is the bid to stage the Olympic Games in 2020. Qatar not merely has ambitions, it realizes its ambitions. And when it does so it is not enough to say that the result is ‘world class’, for Qatar sets out to be a world leader in whatever it puts its hand to. Excellence is the norm. Al Jazeera has established itself as the broadcasting station of choice for many throughout the world. The Doha Museum of Islamic Art is recognized as being second to none. In addition, the scale and standard of development in Doha itself is setting new standards of excellence in the fields of architecture and civil engineering. Thus when Qatar focuses its energies on education and the law, high achievements are expected. I shall have the honour of helping to achieve those expectations when I succeed Lord Woolf as President of Qatar’s new and impressive Civil and Commercial Court. The College of Law at Qatar University is already achieving excellence in the field of legal education. So, naturally, all expect great things of this new International Review of Law and I am delighted to have been invited to welcome it by this foreword. The range of the first edition is both international and topical. Those countries that have experienced the turbulence of the Arab Spring are settling new constitutions, and other countries are bent on constitutional reform designed to avoid such turbulence. So an erudite article on

  5. Managing plutonium in Britain. Current options[Mixed oxide nuclear fuels; Nuclear weapons

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-09-01

    This is the report of a two day meeting to discuss issues arising from the reprocessing of plutonium and production of mixed oxide nuclear fuels in Britain. It was held at Charney Manor, near Oxford, on June 25 and 26, 1998, and was attended by 35 participants, including government officials, scientists, policy analysts, representatives of interested NGO's, journalists, a Member of Parliament, and visiting representatives from the US and Irish governments. The topic of managing plutonium has been a consistent thread within ORG's work, and was the subject of one of our previous reports, CDR 12. This particular seminar arose out of discussions earlier in the year between Dr. Frank Barnaby and the Rt. Hon. Michael Meacher MP, Minister for the Environment. With important decisions about the management of plutonium in Britain pending, ORG undertook to hold a seminar at which all aspects of the subject could be aired. A number of on-going events formed the background to this initiative. The first was British Nuclear Fuels' [BNFL] application to the Environment Agency to commission a mixed oxide fuel [MOX] plant at Sellafield. The second was BNFL's application to vary radioactive discharge limits at Sellafield. Thirdly, a House of Lords Select Committee was in process of taking evidence, on the disposal of radioactive waste. Fourthly, the Royal Society, in a recent report entitled Management of Separated Plutonium, recommended that 'the Government should commission a comprehensive review... of the options for the management of plutonium'. Four formal presentations were made to the meeting, on the subjects of Britain's plutonium policy, commercial prospects for plutonium use, problems of plutonium accountancy, and the danger of nuclear terrorism, by experts from outside the nuclear industry. It was hoped that the industry's viewpoint would also be heard, and BNFL were invited to present a paper, but declined on the grounds that they

  6. Disequilibrium Chemistry in the Solar Nebula and Early Solar System: Implications for the Chemistry of Comets

    Science.gov (United States)

    Fegley, Bruce, Jr.

    1997-12-01

    that polyoxymethylene (polymerized formaldehyde or POM) is a constituent of the C- H-O-N particles emitted from comet P/Halley (e.g., Huebner 1987; Huebner et aL 1987; Mitchell et al. 1987). If actually present in the C-H-O-N particles, POM is also a product of disequilibrating processes which took place in the solar nebula and/or in a presolar environment. Taken together, the observations listed above indicate that a variety of disequilibrating processes such as the kinetic inhibition of thermochemical reactions, grain catalyzed chemistry, lightning induced shock chemistry, and photochemistry played an important role in establishing the chemistry and molecular composition of comet P/Halley in particular and presumably cometary material in general. However, the observational data do not by themselves constrain the timing and/or location of these various processes. This paper reviews the relevant observational data and attempts to quantify as far as possible by using current theoretical models and experimental data the relative importance of equilibrium and disequilibrium processes for the chemistry of comets. "Key" experimental and observational measurements which are important for better constraints on cometary origins are proposed. Finally, important measurements to be made by a comet nucleus sample return mission such as Rosetta are also suggested.

  7. Managing plutonium in Britain. Current options

    International Nuclear Information System (INIS)

    1998-01-01

    This is the report of a two day meeting to discuss issues arising from the reprocessing of plutonium and production of mixed oxide nuclear fuels in Britain. It was held at Charney Manor, near Oxford, on June 25 and 26, 1998, and was attended by 35 participants, including government officials, scientists, policy analysts, representatives of interested NGO's, journalists, a Member of Parliament, and visiting representatives from the US and Irish governments. The topic of managing plutonium has been a consistent thread within ORG's work, and was the subject of one of our previous reports, CDR 12. This particular seminar arose out of discussions earlier in the year between Dr. Frank Barnaby and the Rt. Hon. Michael Meacher MP, Minister for the Environment. With important decisions about the management of plutonium in Britain pending, ORG undertook to hold a seminar at which all aspects of the subject could be aired. A number of on-going events formed the background to this initiative. The first was British Nuclear Fuels' [BNFL] application to the Environment Agency to commission a mixed oxide fuel [MOX] plant at Sellafield. The second was BNFL's application to vary radioactive discharge limits at Sellafield. Thirdly, a House of Lords Select Committee was in process of taking evidence, on the disposal of radioactive waste. Fourthly, the Royal Society, in a recent report entitled Management of Separated Plutonium, recommended that 'the Government should commission a comprehensive review... of the options for the management of plutonium'. Four formal presentations were made to the meeting, on the subjects of Britain's plutonium policy, commercial prospects for plutonium use, problems of plutonium accountancy, and the danger of nuclear terrorism, by experts from outside the nuclear industry. It was hoped that the industry's viewpoint would also be heard, and BNFL were invited to present a paper, but declined on the grounds that they were 'currently involved in a formal

  8. The Scientific Papers of James Clerk Maxwell

    Science.gov (United States)

    Clerk Maxwell, James; Niven, W. D.

    2011-01-01

    homogeneous quadratic functions; 57. On the focal lines of a refracted pencil; 58. An Essay on the mathematical principles of physics. By Rev. James Challis. (Review); 59. On Loschmidt's experiments on diffusion in relation to the kinetic theory of gases; 60. On the final state of a system of molecules in motion subject to forces of any kind; 61. Faraday; 62. Molecules (a lecture); 63. On double refraction in a viscous fluid in motion; 64. On Hamilton's characteristic function for a narrow beam of light; 65. On the relation of geometrical optics to other parts of mathematics and physics; 66. Plateau on soap-bubbles (Review); 67. Grove's Correlation of physical forces (Review); 68. On the application of Kirchhoff's rules for electric circuits to the solution of a geometric problem; 69. Van der Waals on the continuity of the gaseous and liquid states; 70. On the centre of motion of the eye; 71. On the dynamical evidence of the molecular constitution of bodies (a lecture); 72. On the application of Hamilton's characteristic function to the theory of an optical instrument symmetrical about its axis; 73. Atom; 74. Attraction; 75. On Bow's method of drawing diagrams in graphical statics with illustrations from Peaucellier's Linkage; 76. On the equilibrium of heterogeneous substances; 77. Diffusion of gases through absorbing substances; 78. General considerations concerning scientific apparatus; 79. Instruments connected with fluids; 80. Whewell's Writing and correspondence (Review); 81. On Ohm's Law; 82. On the protection of buildings from lightning; 83. Capillary action; 84. Hermann Ludwig Ferdinand Helmholtz; 85. On a paradox in the theory of attraction; 86. On approximate multiple integration between limits by summation; 87. On the unpublished electrical papers of the Hon. Henry Cavendish; 88. Constitution of bodies; 89. Diffusion; 90. Diagrams; 91. Tait's Thermo

  9. Evaluation of a 30-gene paclitaxel, fluorouracil, doxorubicin and cyclophosphamide chemotherapy response predictor in a multicenter randomized trial in breast cancer

    Science.gov (United States)

    Tabchy, Adel; Valero, Vicente; Vidaurre, Tatiana; Lluch, Ana; Gomez, Henry; Martin, Miguel; Qi, Yuan; Barajas-Figueroa, Luis Javier; Souchon, Eduardo; Coutant, Charles; Doimi, Franco D; Ibrahim, Nuhad K; Gong, Yun; Hortobagyi, Gabriel N; Hess, Kenneth R; Symmans, W Fraser; Pusztai, Lajos

    2010-01-01

    Purpose We examined in a prospective, randomized, international clinical trial the performance of a previously defined 30-gene predictor (DLDA-30) of pathologic complete response (pCR) to preoperative weekly paclitaxel and fluorouracil, doxorubicin, cyclophosphamide (T/FAC) chemotherapy, and assessed if DLDA-30 also predicts increased sensitivity to FAC-only chemotherapy. We compared the pCR rates after T/FAC versus FAC×6 preoperative chemotherapy. We also performed an exploratory analysis to identify novel candidate genes that differentially predict response in the two treatment arms. Experimental Design 273 patients were randomly assigned to receive either weekly paclitaxel × 12 followed by FAC × 4 (T/FAC, n=138), or FAC × 6 (n=135) neoadjuvant chemotherapy. All patients underwent a pretreatment FNA biopsy of the tumor for gene expression profiling and treatment response prediction. Results The pCR rates were 19% and 9% in the T/FAC and FAC arms, respectively (pcancers. PMID:20829329

  10. High-Confidence Flow Accelerated Corrosion Screening Technique

    International Nuclear Information System (INIS)

    Ryu, Kyung Ha; Kim, Ji Hak; Hwang, Il Soon; Lee, Na Young; Kim, Ji Hyun

    2008-01-01

    All carbon steel pipes with fluid traveling through it could potentially be threatened by flowing fluid have a potential threat of Flow Accelerated Corrosion (FAC). FAC in a nuclear power plant (NPP) could cause not only pipe failure leading but fatalities sometimes. It is almost impossible to inspect all carbon steel pipes in NPPs, and FAC prediction programs such as CHECWORKS, WATHEC, and BRT-CICERO have limited capability to in predicting FAC area

  11. 48 CFR 301.607-72 - Applicability.

    Science.gov (United States)

    2010-10-01

    ... ACQUISITION REGULATION SYSTEM Career Development, Contracting Authority, and Responsibilities 301.607-72 Applicability. (a) The FAC-P/PM certification prerequisites and continuous learning requirements apply to all HHS employees who seek to obtain a FAC-P/PM certification. Although obtaining a FAC-P/PM certification...

  12. Intuitional experiment and numerical analysis of flow characteristics affected by flow accelerated corrosion in elbow pipe system

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyung Joon [School of Mechanical and Aerospace Engineering, Seoul National University, Gwanak-gu, Seoul 151-744 (Korea, Republic of); Kim, Kyung Hoon, E-mail: kimkh@khu.ac.kr [Department of Mechanical Engineering, Kyung Hee University, Seochun 1, Yongin, Gyeonggi 446-701 (Korea, Republic of)

    2016-05-15

    Highlights: • Wall-thinning erosion of pipelines in plants leads to fatal accidents unexpectedly. • Flow Acceleration Corrosion (FAC) is a main reason of wall-thinning. • For industrial safety, it is necessary to verify the tendency of FAC. • We focused on local wall thinning by FAC with intuitional visualization experiment and numerical analysis in elbow pipe.

  13. Effect of Water Chemistry Factors on Flow Accelerated Corrosion : pH, DO, Hydrazine

    International Nuclear Information System (INIS)

    Lee, Eun Hee; Kim, Kyung Mo; Kim, Hong Pyo

    2013-01-01

    Flow accelerated corrosion(FAC) of the carbon steel piping in pressurized water reactors(PWRs) has been major issue in nuclear industry. Severe accident at Surry Unit 2 in 1986 initiated the worldwide interest in this area. Major parameters influencing FAC are material composition, microstructure, water chemistry, and hydrodynamics. Qualitative behaviors of FAC have been well understood but quantitative data about FAC have not been published for proprietary reason. In order to minimize the FAC in PWRs, the optimal method is to control water chemistry factors. Chemistry factors influencing FAC such as pH, corrosion potential, and hydrazine contents were reviewed in this paper. FAC rate decreased with pH up to 10 because magnetite solubility decreased with pH. Corrosion potential is generally controlled dissolved oxygen (DO) and hydrazine in secondary water. DO increased corrosion potential. FAC rate decreased with DO by stabilizing magnetite at low DO concentration or by formation of hematite at high DO concentration. Even though hydrazine is generally used to remove DO, hydrazine itself thermally decomposed to ammonia, nitrogen, and hydrogen raising pH. Hydrazine could react with iron and increased FAC rate. Effect of hydrazine on FAC is rather complex and should be careful in FAC analysis. FAC could be managed by adequate combination of pH, corrosion potential, and hydrazine

  14. Wetlands Research Program. Corps of Engineers Wetlands Delineation Manual. Appendix C. Sections 1 and 2. Region 6 - Southern Plains.

    Science.gov (United States)

    1987-01-01

    Zandica L. Maryland senna FAG fassutha f11i~iformis L. Cassytha :azyaponia cuinque~ aba (Raf.) Shinners Cayaponia FAC CeLtis !aeviaata Wilid. Sugarberry... Basil FAC P. ternsifoiwn Schrad. Pychanthemum FAC Qu.ercus X beadiei Trelease Beadle oak FACW- Q. bicolor Willd. Swamp white oak FACW+ Q. imbricaria

  15. Model of physico-chemical effect on flow accelerated corrosion in power plant

    International Nuclear Information System (INIS)

    Fujiwara, Kazutoshi; Domae, Masafumi; Yoneda, Kimitoshi; Inada, Fumio

    2011-01-01

    Highlights: → Model of chemical effect on FAC was developed. → Equation to evaluate the dissolved oxygen concentration for FAC suppression was derived. → The model explains the qualitatively the effect of parameters on FAC rate. → Diffusion of soluble species well reproduces the unique FAC behavior. - Abstract: Flow accelerated corrosion (FAC) is caused by the accelerated dissolution of protective oxide film under the condition of high flow rate and has been one of the most important subjects in fossil and nuclear power plants. The dominant factors of FAC are water chemistry, material, and fluid dynamics. Understanding of the thinning mechanism is very important to estimate the quantitative effects of the dominant factors on FAC. In this study, a novel model of chemical effect on FAC under the steady-state condition was developed in consideration of the diffusion of soluble iron and chromium species, dissolved hydrogen, and dissolved oxygen. The formula to evaluate the critical concentration of dissolved oxygen for FAC suppression was derived. The present model reproduced qualitatively the effect of major environmental parameters on FAC rate. The model could explain the following facts. (1) The FAC rate shows a peak around 413 K. (2) The FAC rate decreases with an increase in Cr content. (3) The FAC rate decreases with an increase in pH. (4) The FAC rate decreases with an increase in dissolved oxygen concentration. (5) The maximum of critical dissolved oxygen concentration is observed around 353 K. (6) The critical dissolved oxygen concentration decreases with an increase in pH. We conclude that the diffusion of soluble species from the saturated layer under the steady-state condition well reproduces the unique FAC behavior with variation of water chemistry parameters.

  16. A study on prediction of metal loss by flow-accelerated corrosion in the CANDU NPP secondary piping systems

    International Nuclear Information System (INIS)

    Shim, S. H.; Song, J. S.; Yoon, K. B.; Hwang, K. M.; Jin, T. E.; Lee, S. H.; Kim, W. S.

    2001-01-01

    Flow-Accelerated Corrosion(FAC) is a phenomenon that results in metal loss from piping, vessels, and equipment made of carbon steel. FAC occurs only under certain conditions of flow, chemistry, geometry, and material. Unfortunately, those conditions are in much of the high-energy piping in nuclear and fossil-fueled power plants. Also, for domestic NPP secondary pipings whose operating time become longer, more evidences of FAC have been reported. The authors are studying on FAC management using CHECWORKS, computer code developed by EPRI. This paper is on the prediction results of metal loss by FAC in the one of CANDU type NPP secondary piping systems

  17. SASOP Biological Psychiatry Congress 2013 Abstracts

    Directory of Open Access Journals (Sweden)

    E Allers

    2013-08-01

    for monitoring of breast cancer patients at risk of physical and psychological complications K Grant, F J Cronje, K Botha, J P Apffelstaedt, M J Kotze 19. Unipolar mania reconsidered: Evidence from a South African study C Grobler 20. Antipsychotic-induced movement disorders: Occurence and management P Haddad 21. The place of observational studies in assessing the effectiveness of long-acting injectable antipsychotics P Haddad 22. Molecular mechanisms of d-cycloserine in fear extinction: Insights from RNS sequencing S Hemmings, S Malan-Muller, L Fairbairn, M Jalali, E J Oakeley, J Gamieldien, M Kidd, S Seedat 23. Schizophrenia: The role of inflammation DC Henderson 24. Addictions: Emergent trends and innovations V Hitzeroth 25. The socio-cultural-religious context of biological psychiatric practice B Janse van Rensburg 26. Biochemical markers for identifying risk factors for disability progression in multiple sclerosis S Janse van Rensburg, M J Kotze, F J Cronje, W Davis, K Moremi, M Jalali Sefid Dashti, J Gamieldien, D Geiger, M Rensburg, R van Toorn, M J de Klerk, G M Hon, T Matsha, S Hassan, R T Erasmus 27. Alcohol-induced psychotic disorder: Brain perfusion and psychopathology - before and after antipsychotic treatment G Jordaan, J M Warwick, D G Nel, R Hewlett, R Emsley 28.'Pump and dump': Harm reduction strategies for breastfeeding while using substances L Kramer 29. Adolescent neuropsychiatry - an emerging field in South African adolescent psychiatric services A Lachman 30. Recovery versus remission, or what it means to be healthy for a psychiatric patient? B Latecki 31. Holistic methods utilised to normalise behaviours in youth diagnosed with neuro-biochemical disorders P Macqueen 32. Candidate genes and novel polymorphisms for anxiety disorder in a South African cohort N McGregor, J Dimatelis, S M J Hemmings, C J Kinnear, D Stein, V Russel, C Lochner 33. Higher visual functioning A Moodley 34. The effects of prenatal methylmercury exposure on trace element and

  18. Psychopharmacology 2003 Conference, 10-13 September 2003

    Directory of Open Access Journals (Sweden)

    Diana P Morrison

    2003-09-01

    correlates with altered Neurotransmitter function in maternally separated Rats W M U Daniels, C Y Pietersen, M E Carstens, D J Stein 42. A mechanism for Zinc Toxicity in NeuroBlastoma Cells W M U Daniels, J Hendricks, R Salie, S J Van Rensburg 43. The effects of Hypericum Perforatum, Quercetin and Fluoxetine on receptor densities in the rat brain L Heideman and S Daya 44. Trichotillomania and obsessive-compulsive disorder: Clinical and genetic comparisons withn a South African population S M J Hemmings, C J Kinnear, C Lochner, H Moolman-Smook, D J H Niehaus, V Corfield, D J Stein 45. Expression of Nogo-A in the amphibian central nervous system N. J. Hsu, R Jarvis, D. M. Lang 46. Biochemical model for inflammation of the brain: The role of iron, transferring and Toxiferring in Lipid Peroxidation S J Van Rensburg, R T Erasmus, J M van Zyl, D Hon, W M U Daniels, F C V Potocnik, M J Kotze, N J De Villiers, P R Hurly 47. Improvement in Alzheimer's Disease patients with antioxidant supplementation over 15 months S J van Rensburg, F C V Potocnik, J M Van Zyl, B J Van der Walt, D Hon, A Roos, E Rienhardt, R T Erasmus 48. The Placebo effect - Is it all in the mind? S J van Rensburg, R A  Emsley, C M Smuts, M Kidd, S Van der Merwe, C C Myburgh, P Oosthuizen, H Bleeker 49. Very low serum Iron concentrations in elderly patients with active Carcinoma S J van Rensburg, R Erasmus, D Hon, C Bouwens 50. Melatonin affords protection against Rotenone-induced Neurotoxicity R John, S Daya 51. Effect of enriched environment on Ca uptake via NMDA Receptors into barrel Cortex slices of spontaneously Hypertensive rats M Lehohla, V Russell, L Kellaway 52. Effects of Methylpenidate in a rat model for Attention-Deficit Hyperactivity Disorder G. L. S. Lelaka, V. A. Russel, L. A. Kellaway 53. 6-Hydroxymelatonin converts Fe (III to Fe (II and reduces iron-induced Lipid Peroxidation D S Maharaj, S Daya 54. Metrofinate Potentiates Quinolinic Acid and Potassium Cyanide induced Neurotoxicity A Ramsunder, S

  19. Flow-assisted corrosion of steel and the influence of Cr and Cu additions

    International Nuclear Information System (INIS)

    Cubicciotti, D.

    1988-01-01

    Flow-assisted corrosion (FAC) of steel feedwater lines occurs by dissolution of the surface oxide layer on the steel. The solubility of iron in water under FAC conditions is discussed through the use of potential-pH diagrams (Pourbaix diagrams). Alloying additions of chromium and copper both decrease FAC. An assessment is presented that Cr additions decrease FAC by forming a mixed oxide with iron instead of a pure iron oxide. The solubility of iron from the mixed oxide is smaller than for pure iron oxide and leads to a smaller FAC rate. The stable form of copper under FAC conditions is not the mixed iron-copper oxide but metallic copper, which may act in the underlying steel surface to impede FAC. (orig.)

  20. Seasonal and interplanetary magnetic field dependence of the field-aligned currents for both Northern and Southern Hemispheres

    Directory of Open Access Journals (Sweden)

    D. L. Green

    2009-04-01

    Full Text Available The configuration of the Earth's magnetosphere under various Interplanetary Magnetic Field (IMF and solar wind conditions alters the global distribution of Field-Aligned Currents (FACs at the high latitude ionospheres. We use magnetic field data obtained from the Iridium constellation to extend recent studies that infer the dependence of the global FAC configuration on IMF direction and magnitude, hemisphere and season. New results are a reduced IMF By influence on the FAC configuration for the winter hemisphere and a redistribution of FAC to the nightside for winter relative to the summer hemisphere. These effects are linked to the winter ionosphere conductance distribution being dominated by localised nightside enhancement associated with ionisation from energetic particle precipitation. A comparison of an estimated open-closed field line boundary (OCFLB with the Region 1 FAC locations shows reasonable agreement for summer FAC configurations. However, the OCFLB location is decoupled from the Region 1 FACs in winter, especially for IMF Bz>0.

  1. Mejores prácticas en gestión de proveedores a nivel mundial, aplicables al sistema de Administración de la Relación con el Proveedor (ARP de la Jefatura de Operaciones Logísticas (JOL de la Fuerza Aérea Colombiana (FAC

    Directory of Open Access Journals (Sweden)

    Italo Arrazola Aguado

    2014-01-01

    Full Text Available Dentro de la administración de la cadena de abastecimiento ó Supply Chain Management (SCM, se destaca la gestión de proveedores como una de las actividades más críticas para su establecimiento efectivo. Por lo anterior, el presente artículo busca aproximarse al estado del arte en gestión de proveedores, utilizando como referencia revistas internacionales especializadas en el tema, ofreciendo así una base de referencia en futuras investigaciones relacionadas. En este sentido, se propone un conjunto de alternativas para estructurar un procedimiento general, que permita la adecuada toma de decisiones en cuanto a los proveedores tanto en la Jefatura de Operaciones Logísticas de la Fuerza Aérea Colombiana, como en cualquier organización con el ajuste apropiado.

  2. A Study of the Physical Fitness and Influencing Fac-tors of Young PE Teachers in Higher Educational In-stitutions of Jiangsu Province%江苏省普通高校中青年体育教师体能现状及影响因素研究

    Institute of Scientific and Technical Information of China (English)

    李勇; 刘健

    2014-01-01

    以江苏省部分高校中青年体育教师体能测试的结果为研究对象,对其体能现状进行分析,发现体能测试成绩的高低与年龄的增长,不同专项的差异,男女性别的差异有相关性。但最主要因素是自身对体能的认知和体能训练的习惯。根据目前现状,有关部门应制定相关政策法规,定期组织体育教师进行体能训练与测试,并根据测试结果有相应的奖惩制度,督促体育教师加强体能训练,并适当合理安排教师的工作量,改善工作环境,提高福利待遇。%This essay analyses the results of young PE teachers’ fitness conditions in several schools in Jiangsu, and concludes that the scores in fitness tests are relevant to parameters such as age, sports, and gender with the training of physical fitness being the key factor. Based on current situation, the government departments concerned should make relevant laws and policies and organize regu-lar physical training and fitness tests for PE teachers. In addition,a corresponding system of rewards and penalties should also be established to urge PE teachers to improve their fitness conditions. Meanwhile, teaching staff should be wisely arranged to various teaching tasks so as to im-prove their teaching conditions and warfare system.

  3. Mejores prácticas en gestión de proveedores a nivel mundial, aplicables al sistema de Administración de la Relación con el Proveedor (ARP) de la Jefatura de Operaciones Logísticas (JOL) de la Fuerza Aérea Colombiana (FAC)

    OpenAIRE

    Italo Arrazola Aguado

    2014-01-01

    Dentro de la administración de la cadena de abastecimiento ó Supply Chain Management (SCM), se destaca la gestión de proveedores como una de las actividades más críticas para su establecimiento efectivo. Por lo anterior, el presente artículo busca aproximarse al estado del arte en gestión de proveedores, utilizando como referencia revistas internacionales especializadas en el tema, ofreciendo así una base de referencia en futuras investigaciones relacionadas. En este sentido, se propone un co...

  4. Functionalized granular activated carbon and surface complexation with chromates and bi-chromates in wastewater

    International Nuclear Information System (INIS)

    Singha, Somdutta; Sarkar, Ujjaini; Luharuka, Pallavi

    2013-01-01

    Cr(VI) is present in the aqueous medium as chromate (CrO 4 2− ) and bi-chromate (HCrO 4 − ). Functionalized granular activated carbons (FACs) are used as adsorbents in the treatment of wastewaters containing hexavalent chromium. The FACs are prepared by chemical modifications of granular activated carbons (GACs) using functionalizing agents like HNO 3 , HCl and HF. The Brunauer, Emmett and Teller surface areas of FAC-HCl (693.5 m 2 /g), FAC-HNO 3 (648.8 m 2 /g) and FAC-HF (726.2 m 2 /g) are comparable to the GAC (777.7 m 2 /g). But, the adsorption capacity of each of the FAC-HNO 3 , FAC-HCl and FAC-HF is found to be higher than the GAC. The functional groups play an important role in the adsorption process and pH has practically no role in this specific case. The FACs have hydrophilic protonated external surfaces in particular, along with the functional surface sites capable to make complexes with the CrO 4 2− and HCrO 4 − present. Surface complex formation is maximized in the order FAC-HNO 3 > FAC-HF > FAC-HCl, in proportion to the total surface acidity. This is also confirmed by the well-known pseudo second-order kinetic model. Physi-sorption equilibrium isotherms are parameterized by using standard Freundlich and Langmuir models. Langmuir fits better. The formation of surface complexes with the functional groups and hexavalent chromium is also revealed in the images of field emission scanning electron micrograph; energy dispersive X-ray spectroscopy and Fourier transform infrared spectroscopy analysis after adsorption. The intra-particle diffusion is not the only rate-controlling factor. The Boyd's film diffusion model fits very well with R 2 as high as 98.1% for FAC-HNO 3 . This result demonstrates that the functionalization of the GAC by acid treatments would increase the diffusion rate, predominantly with a boundary layer diffusion effect. - Highlights: ► Physico-chemical adsorption using functionalized activated carbon (FACs) is applied. ► FACs

  5. A Comprehensive Analysis of Multiscale Field-Aligned Currents: Characteristics, Controlling Parameters, and Relationships

    Science.gov (United States)

    McGranaghan, Ryan M.; Mannucci, Anthony J.; Forsyth, Colin

    2017-12-01

    We explore the characteristics, controlling parameters, and relationships of multiscale field-aligned currents (FACs) using a rigorous, comprehensive, and cross-platform analysis. Our unique approach combines FAC data from the Swarm satellites and the Advanced Magnetosphere and Planetary Electrodynamics Response Experiment (AMPERE) to create a database of small-scale (˜10-150 km, 250 km) FACs. We examine these data for the repeatable behavior of FACs across scales (i.e., the characteristics), the dependence on the interplanetary magnetic field orientation, and the degree to which each scale "departs" from nominal large-scale specification. We retrieve new information by utilizing magnetic latitude and local time dependence, correlation analyses, and quantification of the departure of smaller from larger scales. We find that (1) FACs characteristics and dependence on controlling parameters do not map between scales in a straight forward manner, (2) relationships between FAC scales exhibit local time dependence, and (3) the dayside high-latitude region is characterized by remarkably distinct FAC behavior when analyzed at different scales, and the locations of distinction correspond to "anomalous" ionosphere-thermosphere behavior. Comparing with nominal large-scale FACs, we find that differences are characterized by a horseshoe shape, maximizing across dayside local times, and that difference magnitudes increase when smaller-scale observed FACs are considered. We suggest that both new physics and increased resolution of models are required to address the multiscale complexities. We include a summary table of our findings to provide a quick reference for differences between multiscale FACs.

  6. Field-aligned currents observed by CHAMP during the intense 2003 geomagnetic storm events

    Directory of Open Access Journals (Sweden)

    H. Wang

    2006-03-01

    Full Text Available This study concentrates on the characteristics of field-aligned currents (FACs in both hemispheres during the extreme storms in October and November 2003. High-resolution CHAMP magnetic data reflect the dynamics of FACs during these geomagnetic storms, which are different from normal periods. The peak intensity and most equatorward location of FACs in response to the storm phases are examined separately for both hemispheres, as well as for the dayside and nightside. The corresponding large-scale FAC peak densities are, on average, enhanced by about a factor of 5 compared to the quiet-time FACs' strengths. And the FAC densities on the dayside are, on average, 2.5 times larger in the Southern (summer than in the Northern (winter Hemisphere, while the observed intensities on the nightside are comparable between the two hemispheres. Solar wind dynamic pressure is correlated with the FACs strength on the dayside. However, the latitudinal variations of the FACs are compared with the variations in Dst and the interplanetary magnetic field component Bz, in order to determine how these parameters control the large-scale FACs' configuration in the polar region. We have determined that (1 the equatorward shift of FACs on the dayside is directly controlled by the southward IMF Bz and there is a saturation of the latitudinal displacement for large value of negative Bz. In the winter hemisphere this saturation occurs at higher latitudes than in the summer hemisphere. (2 The equatorward expansion of the nightside FACs is delayed with respect to the solar wind input. The poleward recovery of FACs on the nightside is slower than on the dayside. The latitudinal variations on the nightside are better described by the variations of the Dst index. (3 The latitudinal width of the FAC region on the nightside spreads over a wide range of about 25° in latitude.

  7. Mass transfer effects in feeder flow-accelerated corrosion wall thinning

    International Nuclear Information System (INIS)

    Pietralik, J.

    2008-01-01

    Flow conditions play a dominant role in Flow-Accelerated Corrosion (FAC) under certain conditions, e.g., in CANDU feeders. While chemistry and materials set the overall potential for FAC, flow conditions determine the local distribution of wall thinning. Recent plant data of feeders and laboratory tests confirms that there is a close relationship between local flow conditions, expressed by mass transfer coefficient, and FAC rate in CANDU feeder bends. The knowledge of local effects can be useful for minimizing the number of inspected components, predicting the location of the highest FAC rate for a given piping component, and determining what components or feeders should be replaced. A similar evaluation applies also to FAC in heat transfer equipment such as heat exchangers and steam generators. The objective of this paper is to examine the relationship between FAC rate and local mass transfer parameters. For FAC where the flow is dominant, the FAC rate is proportional to mass flux of ferrous ions. The mass flux is the product of the mass transfer coefficient and the concentration difference, or degree of saturation. The mass transfer coefficient describes the intensity of the transport of corrosion products (ferrous ions) from the oxide-water interface into the bulk water. Therefore, this parameter can be used for predicting the local distribution of FAC rate in the mass-transfer controlled FAC. The degree of saturation reduces the mass flux, thus reducing the FAC rate. This effect can be significant in long piping, e.g., in outlet feeders. The paper presents plant and laboratory evidence for the relationship between local mass transfer conditions and the FAC rate. It shows correlations for mass transfer coefficient in components that are highly susceptible to FAC and most important flow parameters that affect mass transfer coefficient. The role of surface roughness, wall shear stress, and local turbulence is also discussed. (author)

  8. Bilimsel Toplantı Duyuruları

    Directory of Open Access Journals (Sweden)

    Adli Tıp Uzmanları Derneği ATUD

    2005-12-01

    .casey@rcpath.org Advances in Microscopical Imaging - Applications in Forensics Meeting 17 October 2006, United Kingdom Further information : Cranfield University, Shrivenham, Wiltshire. Allison Winton, Exhibitions Manager at Royal Microscopical Society Email: allison@rms.org Tel: 01865 254764, RMS Office: 01865 254760 Improving Emergency Response, Emergency Services Show and Conference 2006 19-\t20 October 2006, United Kingdom Further information : Royal Horticultural Halls, London The 32nd Annual Northeastern Association of Forensic Scientists 1-4 November 2006, Further information : Tarrytown DoubleTree Hotel in Westchester County, NY. Elayne Schwartz ess6@westchestergov.com Mediterranean Academy of Forensic Sciences “Developments in Forensic Sciences” 20-\t23 Sept 2006, Malta Further information : Suncrest Hotel Malta, Mrs. Marisa Cassar B.Pharm (Hons mafsworkshop@yahoo.co.uk EAFS 2006 4. Europen Academic of Forensic Science Conference June 13-16, Helsinki Further information : National Bureau of Investigation, Crime Laboratory Dr Erkki Sippola Mrs Oili Ruuskanen Phone +358 9 8388 661 Fax +358 9 8388 6447 E-mail erkki.sippola@krp.poliisi.fi oili.ruuskanen@krp.poliisi.fi VII. Adli Bilimler Kongresi 11-14 Mayıs, Konya Rixos Otel-Konya İletişim: Uzm.Dr. K.Hakan Doğan Selçuk Üniversitesi Meram Tıp Fakültesi Adli Tıp Anabilim Dalı, 42080, Meram/KONYA Tel: (0 332 223 73 29-223 67 52-223 66 51 Gsm: 0505 447 08 83-0542 232 92 81-0536 487 31 47 Faks: 0 332 223 61 81 (Adli Tıp Anabilim Dalı Dikkatine E-posta: doktor2000@e-kolay.net Web: www.atud.org 42. Ulusal Psikiyatri Kongresi 01-05 Kasım 2006, İstanbul “Yaşam Boyu Psikiyatri: Araştırmadan Uygulamaya” İletişim: Hilton Convention Center,İstanbul http:/ / www.psikiyatriistanbul2006.org 6. Cinsellik Ve Cinsel Tedaviler Ulusal Kongresi 24-26 Kasım 2006, İstanbul İstanbul Ceylan Inter-Continental İletişim: Doğan Şahin e-mail: sahind@istanbul.edu.tr dsahin60@tnn.net web: www.cetad.org.tr 3. Ulusal Ba

  9. The 3.26-3.24 Ga Barberton asteroid impact cluster: Tests of tectonic and magmatic consequences, Pilbara Craton, Western Australia

    Science.gov (United States)

    Glikson, Andrew; Vickers, John

    2006-01-01

    Creek Group-GCG [R. M. Hill, Stratigraphy, structure and alteration of hanging wall sedimentary rocks at the Sulphur Springs volcanogenic massive sulphide (VMS) prospect, east Pilbara Craton, Western Australia. B.Sc Hon. Thesis, University of Western Australia (1997) 67 pp.; M.J. Van Kranendonk, A.H. Hickman, R.H. Smithies, D.R. Nelson, Geology and tectonic evolution of the Archaean north Pilbara terrain, Pilbara Craton, Western Australia, Econ. Geol. 97 (2002) 695-732; M.J. Van Kranendonk, Geology of the North Shaw 1 : 100 000 Sheet. Geological Survey Western Australia 1 : 100 000 Geological Series (2000) 86 pp., R. Buick, C.A.W. Brauhart, P. Morant, J.R. Thornett, J.G. Maniew, J.G. Archibald, M.G. Doepel, I.R. Fletcher, A.L. Pickard, J.B. Smith, M.B. Barley, N.J. McNaughton, D.I. Groves, Geochronology and stratigraphic relations of the Sulphur Springs Group and Strelley Granite: a temporally distinct igneous province in the Archaean Pilbara Craton, Australia, Precambrian Res. 114 (2002) 87-120]). The structure and scale of the olistostrome, not seen elsewhere in the Pilbara Craton, is interpreted in terms of intense faulting and rifting, supported by topographic relief represented by deep incision of overlying arenites (Corboy Formation) into underlying units [M.J. Van Kranendonk, Geology of the North Shaw 1 : 100 000 Sheet. Geological Survey Western Australia 1 : 100 000 Geological Series (2000) 86 pp.]. The age overlaps between (1) 3.255 ± 4-3.235 ± 3 Ga peak igneous activity represented by the SSG and the Cleland plutonic suite (Pilbara Craton) and the 3.258 ± 3 Ga S2 Barberton impact unit, and (2) 3.235 ± 3 Ga top SSG break and associated faulting and the 3.243 ± 4 S3-S4 Barberton impact units may not be accidental. Should correlations between the Barberton S2-S4 impact units and magmatic and tectonic events in the Pilbara Craton be confirmed, they would imply impact-triggered reactivation of mantle convection, crustal anatexis, faulting and strong vertical

  10. Baseline assessments for coral reef community structure and demographics on West Maui

    Science.gov (United States)

    Vargas-Angel, Bernardo; White, Darla; Storlazzi, Curt; Callender, Tova; Maurin, Paulo

    2017-01-01

    and sediment loading conditions, the coral-rich habitats in the Wahikuli and Honōkowai Watersheds are probably at greatest risk, given they harbor the most prominent and well-developed reefs in the region, characterized by the highest coral cover, colony densities, and structural complexity.

  11. Pesticide residue profile and nutrient characteristics of the Densu River Basin in Ghana

    International Nuclear Information System (INIS)

    Fianko, J.R.

    2010-01-01

    -chlordane, endrin and δ-HCH were detected in fish, water and sediment samples. Aldrin and dieldrin levels detected were above the recommended limit of 0.03 μL -1 with endosulfan, endrin and chlordane registering levels above their recommended limits of 20.0μL -1 and 0.2 μL -1 respectively for drinking water. Pesticide residues in fish samples varied between 0.10 μgKg -1 to 30.90 μgKg -1 . The highest level was detected in Hepsetus odoe (HO-N). Contamination pattern of pesticide residues in fish samples was generally in the order of p'p'-DDE > heptachlor > γ- HCH > p'p'-DDT > endosulfan Sulphate > α-endosulfan > δ- HCH > γ-chlordane > dieldrin > endrin ketone > methoxychlor > endrin > aldrin > endrin aldehyde. Data obtained from the field survey regarding safe use of pesticides, toxicity awareness and symptoms among farmers indicated that a very high proportion of farmers were at high risk of pesticide poisoning from occupational exposure. More than 90% of farm workers did not practice safety precaution during pesticide formulation and application leading to considerable prevalence of pesticide related illness in this agricultural community. The presence of pesticide residues in fish was of further concern because fish is the main protein diet for humans in the basin. The estimated dose for aldrin, methoxychlor, γ-chlordane, endrin aldehyde, endrin ketone, endrin, p'p'-DDT and δ-HCH do not pose a direct hazard to human health, although present in fish samples since the values registered were lower than the reference doses. However, γ- HCH, heptachlor, α-endosulfan, endosulfan sulphate, p'p'-DDE and dieldrin levels exceeded the reference dose, indicating a great potential for systemic toxicity in children who are considered to be the most vulnerable population subgroup. In children, between the ages of 0 - 1year, the hazard indices of 2.64, 1.720, 1.736 and 0.792 were computed for α-endosulfan, heptachlor, endosulfan sulphate and dieldrin respectively while for

  12. Application of numerical analysis technique to make up for pipe wall thinning prediction program

    International Nuclear Information System (INIS)

    Hwang, Kyeong Mo; Jin, Tae Eun; Park, Won; Oh, Dong Hoon

    2009-01-01

    Flow Accelerated Corrosion (FAC) leads to wall thinning of steel piping exposed to flowing water or wet steam. Experience has shown that FAC damage to piping at fossil and nuclear plants can lead to costly outages and repairs and can affect plant reliability and safety. CHEWORKS have been utilized in domestic nuclear plants as a predictive tool to assist FAC engineers in planning inspections and evaluating the inspection data to prevent piping failures caused by FAC. However, CHECWORKS may be occasionally left out local susceptible portions owing to predicting FAC damage by pipeline group after constructing a database for all secondary side piping in nuclear plants. This paper describes the methodologies that can complement CHECWORKS and the verifications of the CHECWORKS prediction results in terms of numerical analysis. FAC susceptible locations based on CHECWORKS for the two pipeline groups of a nuclear plant was compared with those of numerical analysis based on FLUENT.

  13. Supplementation of Flow Accelerated Corrosion Prediction Program Using Numerical Analysis Technique

    International Nuclear Information System (INIS)

    Hwang, Kyeong Mo; Jin, Tae Eun; Park, Won; Oh, Dong Hoon

    2010-01-01

    Flow-accelerated corrosion (FAC) leads to thinning of steel pipe walls that are exposed to flowing water or wet steam. From experience, it is seen that FAC damage to piping at fossil and nuclear plants can result in outages that require expensive repairs and can affect plant reliability and safety. CHECWORKS have been utilized in domestic nuclear plants as a predictive tool to assist FAC engineers in planning inspections and evaluating the inspection data so that piping failures caused by FAC can be prevented. However, CHECWORKS may be occasionally ignore local susceptible portions when predicting FAC damage in a group of pipelines after constructing a database for all the secondary side piping in nuclear plants. This paper describes the methodologies that can complement CHECWORKS and the verifications of CHECWORKS prediction results using numerical analysis. FAC susceptible locations determined using CHECWORKS for two pipeline groups of a nuclear plant was compared with determined using the numerical-analysis-based FLUENT

  14. Environmental Assessment: 13th Street Bridge Emergency Repair and Retrofit Vandenberg Air Force Base California

    Science.gov (United States)

    2003-06-23

    project site. • Biological hazards, including vegetation (i.e., poison oak and stinging nettle ), animals (i.e., insects , spiders, and snakes), and 4-18...channel, and in dryer areas of the site. Herbaceous species in the understory include stinging nettle (Urtica dioica), California blackberry (Rubus...Nightshade FAC/FACU Poison oak Nightshade FAC/FACU Stinging nettle FACW Cockle-bur FAC+ COMMENTS Likely C. Canadensis Most E/eocharis spp

  15. The low-latitude boundary layer at mid-altitiudes: Relation to large-scale Birkeland currents

    International Nuclear Information System (INIS)

    Woch, J.; Yamauchi, M.; Lundin, R.; Potemra, T.A.; Zanetti, L.J.

    1993-01-01

    In this work the authors seek to test a projected relationship between the low latitude boundary layer (LLBL) and field aligned currents (FAC), or Birkeland currents. They use the procedure developed by Woch and Lundin for identifying LLBL boundaries. They look for correlations between properties of the FAC and properties of the LLBL. Their results show that in most cases the FAC observed are totally inside the region which exhibits LLBL plasma precipitation. The authors argue that within the biases to their data because of its source, and relative sensitivities, their conclusions support earlier work which argues for the LLBL acting as a source region for FAC features

  16. SWMF simulation of field-aligned currents for a varying northward and duskward IMF with nonzero dipole tilt

    Directory of Open Access Journals (Sweden)

    H. Wang

    2008-06-01

    Full Text Available This study concentrates on the FACs distribution for the varying northward and duskward interplanetary magnetic field (IMF conditions when the dipole tilt is nonzero. A global MHD simulation (the Space Weather Modeling Framework, SWMF has been used to perform this study. Hemispheric asymmetry of the time evolution of northward IMF Bz (NBZ FACs is found. As the IMF changes from strictly northward to duskward, NBZ FACs shift counterclockwise in both summer and winter hemispheres. However, in the winter hemisphere, the counterclockwise rotation prohibits the duskward NBZ FACs from evolving into the midday R1 FACs. The midday R1 FACs seem to be an intrusion of dawnside R1 FACs. In the summer hemisphere, the NBZ FACs can evolve into the DPY FACs, consisting of the midday R0 and R1 FACs, after the counterclockwise rotation. The hemispheric asymmetry is due to the fact that the dipole tilt favors more reconnection between the IMF and the summer magnetosphere. When mapping the NBZ and DPY FACs into the magnetosphere it is found that the NBZ currents are located on both open and closed field lines, irrespective of the IMF direction. For the DPY FACs the hemispheric asymmetry emerges: the midday R1 FACs and a small part of R0 FACs are on closed field lines in the winter hemisphere, while a small part of the midday R1 FACs and all the R0 FACs are on open field lines in the summer hemisphere. Both IMF By and dipole tilt cause the polar cap hemispheric and local time asymmetric. When the IMF is northward, the summer polar cap is closed on the nightside while the winter polar cap is open. The polar cap boundary tends to move equatorward as the IMF rotates from northward to duskward, except in the summer hemisphere, the polar cap on the dawnside shifts poleward when the clock angle is less than 10°. The further poleward displacement of the polar cap boundary on one oval side is caused by the twist of the tail plasma sheet, which is in accordance with the

  17. IMF By-Related Cusp Currents Observed from the Ørsted Satellite and from Ground

    DEFF Research Database (Denmark)

    Stauning, P.; Primdahl, Fritz; Watermann, J.

    2001-01-01

    Orsted is the first satellite to conduct high-precision magnetometer observations from low-altitude noonmidnight orbits passing through the polar cusp regions. Field-aligned currents (FAC) derived from Orsted magnetic field measurements have been combined with ionospheric current patterns inferred...... statistical analysis defines for the noon region the variations in FAC latitude with IMF B-Z. Comparisons with the statistical cusp location indicate that the more equatorward region of IMF B-gamma-while the more B related FAC is located on field lines closing at the dayside poleward FAC are on "open" field...

  18. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Canada) International Fellows Associate Fellows Residents Medical Students Affiliate Members ACS Insurance Programs ACS Discount Programs FACS Resources Career Connection Update ...

  19. Your Lung Operation: After Your Operation

    Medline Plus

    Full Text Available ... Canada) International Fellows Associate Fellows Residents Medical Students Affiliate Members ACS Insurance Programs ACS Discount Programs FACS Resources Career Connection Update ...

  20. Flow-accelerated corrosion in power plants. Revision 1

    International Nuclear Information System (INIS)

    Chexal, B.; Horowitz, J.; Dooley, B.

    1998-07-01

    Flow-Accelerated Corrosion (FAC) is a phenomenon that results in metal loss from piping, vessels, and equipment made of carbon steel. FAC occurs only under certain conditions of flow, chemistry, geometry, and material. Unfortunately, those conditions are common in much of the high-energy piping in nuclear and fossil-fueled power plants. Undetected, FAC will cause leaks and ruptures. Consequently, FAC has become a major issue, particularly for nuclear plants. Although major failures are rare, the consequences can be severe. In 1986, four men in the area of an FAC-induced pipe rupture were killed. Fossil plants too, are subject to FAC. In 1995, a failure at a fossil-fired plant caused two fatalities. In addition to concerns about personnel safety, FAC failures can pose challenges to plant safety. Regulatory agencies have therefore required nuclear utilities to institute formal programs to address FAC. Finally, a major FAC failure (like the one that happened in 1997 at a US nuclear power plant) can force a plant to shutdown and purchase replacement power at a price approaching a million dollars per day depending upon the MWe rating of the plant. A great deal of time and money has been spent to develop the technology to predict, detect, and mitigate FAC in order to prevent catastrophic failures. Over time, substantial progress has been made towards understanding and preventing FAC. The results of these efforts include dozens of papers, reports, calculations, and manuals, as well as computer programs and other tools. This book is written to provide a detailed treatment of the entire subject in a single document. Any complex issue requires balancing know-how, the risk of decision making, and a pragmatic engineering solution. This book addresses these by carrying out the necessary R and D and engineering along with plant knowledge to cover all quadrants of Chexal's four quadrant known-unknown diagram, as seen in Figure i

  1. Extension Agent Knowledge and Programming Behaviors Regarding Healthy Lifestyles Education in Georgia

    Science.gov (United States)

    Lynch, Dana R.; Fuhrman, Nicholas E.; Duncan, Dennis W.; Hanula, Gail M.

    2015-01-01

    Healthy lifestyles education (HLE) is defined as nutrition and physical activity education aimed at controlling or preventing serious health issues. The purpose of the study reported here was to determine knowledge and behaviors of Extension Family and Consumer Sciences (FACS) and 4-H agents concerning HLE. Eighty-five and 86% of FACS and 4-H…

  2. Flow Accelerated Corrosion: Effect of Water Chemistry and Database Construction

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Eun Hee; Kim, Kyung Mo; Lee, Gyeong Geun; Kim, Dong Jin [KAERI, Daejeon (Korea, Republic of)

    2016-05-15

    Flow accelerated corrosion (FAC) of carbon steel piping in pressurized water reactors (PWRs) has been a major issue in nuclear industry. Severe accidents at Surry Unit 2 in 1986 and Mihama Unit 3 in 2004 initiated the world wide interest in this area. FAC is a dissolution process of the protective oxide layer on carbon steel or low-alloy steel when these parts are exposed to flowing water (single-phase) or wet steam (two-phase). In a single-phase flow, a scalloped, wavy, or orange peel and in a two-phase flow, tiger striping is observed, respectively. FAC is affected by many parameters, like material composition, pH, dissolved oxygen (DO), flow velocity, system pressure, and steam quality. This paper describes the water chemistry factors influencing on FAC and the database is then constructed using literature data. In order to minimize FAC in NPPs, the optimal method is to control water chemistry parameters. However, quantitative data about FAC have not been published for proprietary reason even though qualitative behaviors of FAC have been well understood. A database was constructed using experimental data in literature. Accurate statistical analysis will be performed using this database to identify the relationship between the FAC rate and test environment.

  3. Field-aligned currents' scale analysis performed with the Swarm constellation

    DEFF Research Database (Denmark)

    Lühr, Hermann; Park, Jaeheung; Gjerløv, Jesper Wittendorff

    2015-01-01

    We present a statistical study of the temporal- and spatial-scale characteristics of different field-aligned current (FAC) types derived with the Swarm satellite formation. We divide FACs into two classes: small-scale, up to some 10 km, which are carried predominantly by kinetic Alfve´n waves...

  4. 76 FR 65504 - Proposed Agency Information Collection

    Science.gov (United States)

    2011-10-21

    ..., 888 First Street, NE., Washington, DC 20426. FOR FURTHER INFORMATION CONTACT: Ellen Brown may be...-1 and 009-1 FAC-009-1 R1 Generator owners......... None, this requirement Retention period is derived from R1 of increased by 2 years. FAC-008-1. R2 Generator owners......... None, this requirement...

  5. Estudio de Clamydia psittaci mediante inmunomicroscopía electrónica / Antonio J. Buendía Marín ; director Jesús Salinas Lorente, Joaquín Sánchez Campillo.

    OpenAIRE

    Buendía Marín, Antonio Julian

    1998-01-01

    Tesis-Universidad de Murcia. Consulte la tesis en: BCA. GENERAL. ARCHIVO UNIVERSITARIO. T.M.-1679. Consulte la tesis en: BCA. GENERAL. Fac. Veterinaria. Departamentos. E002B TESIS 80. Consulte la tesis en: BCA. GENERAL. Fac. Veterinaria. Sala de estudio. Tesis-V 110.

  6. 76 FR 46206 - NASA Implementation of Federal Acquisition Regulation (FAR) Award Fee Language Revision

    Science.gov (United States)

    2011-08-02

    ... of Federal Acquisition Regulation (FAR) Award Fee Language Revision AGENCY: National Aeronautics and... Acquisition Circular (FAC) 2005-46. DATES: Effective Date: August 2, 2011. FOR FURTHER INFORMATION CONTACT... on February 8, 2011 (76 FR 6696) implementing Federal Acquisition Circular (FAC) 2005-46 which...

  7. 76 FR 6696 - NASA Implementation of Federal Acquisition Regulation (FAR) Award Fee Language Revision

    Science.gov (United States)

    2011-02-08

    ... of Federal Acquisition Regulation (FAR) Award Fee Language Revision AGENCY: National Aeronautics and... (NFS) to implement the FAR Award Fee revision issued in Federal Acquisition Circular (FAC) 2005-46.... Background Federal Acquisition Circular (FAC) 2005-46 significantly revised FAR Parts 16.305, 16.401, and 16...

  8. Airpower and the 1972 Easter Offensive

    Science.gov (United States)

    2006-06-16

    so intimately familiar with the topic. Colonel David “ El Cid” Neuenswander, a combat veteran fighter pilot, was a former commander of the United...were the O-2 and the OV-10 Bronco . VNAF FACs were still using the older 0-1s. The fixed-wing gunship pilots also became FAC-A qualified. US Deploys

  9. 2005 NDIA Combat Vehicles Conference. Volume 1. Wednesday

    Science.gov (United States)

    2005-09-22

    supporting arms under armor (FO/FAC) helpful • Mobile Data Automated Communications Terminal (MDACT) • Useful if connectivity can be maintained • Consider...other uses • Ability to coordinate supporting arms under armor (FO/FAC) helpful • Mobile Data Automated Communications Terminal (MDACT) • Useful if

  10. An evaluation of the accuracy of labeling of percent sodium hypochlorite on various commercial and professional sources: is sodium hypochlorite from these sources equally suitable for endodontic irrigation?

    NARCIS (Netherlands)

    van der Waal, S.V.; van Dusseldorp, N.E.; de Soet, J.J.

    2014-01-01

    Introduction The shelf life of sodium hypochlorite (NaOCl) is limited, and a previous article showed that there can be a discrepancy between the expected concentration of free available chlorine (FAC) and the actual FAC concentration in NaOCl solutions intended for endodontic irrigation. The current

  11. Experiment list: SRX1131949 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pre-PB || cell sorting strategy=CD138–GFP+CD22- FACS-sorted || chip antibody=H3K2.../6 || genotype/background=Blimp1(GFP/+) || cell preparation=4-day LPS stimulation, FACS sorted || cell type=

  12. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 40; Issue 4 ... Nacional de Investigaciones Científicas y Técnicas), A4408FVY Salta, Argentina; Fac. Ingeniería, Universidad Nacional de Salta, A4408FVY Salta, Argentina; Fac.

  13. Dollar Summary of Federal Supply Classification and Service Category by Company, FY83, Part 6 (W061-Z299).

    Science.gov (United States)

    1983-01-01

    RENT OF FAC /FUEL SUPPLY 29 X299 AUTO TECHNIQUE BELGIQUE S A BELGIUM ARMY LEASE-RENT OF FAC /OTHER NON-BLDG STRUCT 31 HOFFMAN CO VIRGINIA ARMY LEASE...HARRISON & PALMI RIDGE ELECTRICAL E INC MISSOURI ARMY CONSTR: CONSTRUCTION/PARFING FACILITIES $ 123 SUSSEX ELECTRICO C MARYLAND ARMY CONSTR: CONSTRUCTION

  14. F-Area Acid/Caustic Basin groundwater monitoring report. Second quarter 1994

    International Nuclear Information System (INIS)

    1994-09-01

    During second quarter 1994, samples from the FAC monitoring wells at the F-Area Acid/Caustic Basin were collected and analyzed for herbicides/pesticides, indicator parameters, metals, nitrate, radionuclide indicators, volatile organic compounds, and other constituents. Piezometer FAC 5P and monitoring well FAC 6 were dry and could not be sampled. Analytical results that exceeded final Primary Drinking Water Standards (PDWS), other Savannah River Site (SRS) Flag 2 criteria, or the SRS turbidity standard of 50 NTU during the quarter were as follows: gross alpha exceeded the final PDWS and aluminum, iron, manganese, and total organic halogens exceeded the SRS Flag 2 criteria in one or more of the FAC wells. Turbidity exceeded the SRS standard in well FAC 3. Groundwater flow direction and rate in the water table beneath the F-Area Acid/Caustic Basin were similar to past quarters

  15. Field-aligned current signatures during the March 13-14, 1989, great magnetic storm

    International Nuclear Information System (INIS)

    Fujii, R.; Fukunishi, H.; Kokubun, S.; Sugiura, M.; Tohyama, F.; Hayakawa, H.; Tsuruda, K.; Okada, T.

    1992-01-01

    Characteristics of field-aligned currents (FACs) in the evening and morning regions during the March 13-14, 1989, great magnetic storm have been determined using magnetic and electric field data obtained from the EXOS D spacecraft. This storm began with an SSC at 0128 UT on March 13, and the second SSC occurred at 0747 UT on the same day. The storm continued until March 14. The equatorward boundary of the FAC region began to move equatorward right after the first SSC in both the evening and morning sectors, but the poleward boundary did not immediately respond to the SSC. The equatorward boundary of the FAC system reached as low as below 48 degree invariant latitude, which corresponds to L = 2.2, and the latitudinal width of the FAC region increased greatly, particularly in the morning sector (∼33 degree in invariant latitude). In the evening sector the conventional current system characterized by a pair of upward region 1 and downward region 2 FACs changed into complicated patterns consisting of many pairs of upward and downward FACs with the development of the storm, particularly around 22 UT on March 13 when an intense eastward electrojet was observed as low as 50 degree invariant latitude on the ground. In the morning sector an additional large-scale upward FAC was observed poleward of the conventional downward region 1 and upward region 2 FAC system throughout the storm. In addition, a pair of FACs with a narrow latitudinal width (∼1.5 degree) was observed at the poleward boundary of the extra upward FAC

  16. Local effects in flow-accelerated corrosion wall thinning

    International Nuclear Information System (INIS)

    Pietralik, J.

    2006-01-01

    'Full text:' There is enough evidence that flow conditions play the dominant role locally in Flow-Accelerated Corrosion (FAC) under certain conditions, e.g., in CANDU feeders. While chemistry and materials set the overall potential for FAC, which can be low or high, flow conditions determine the local distribution of wall thinning. This relationship is not new and recent accurate measurements of FAC rate of a plant feeder bend confirm that the relationship between flow local conditions expressed by local mass transfer coefficient and FAC rate in CANDU feeder bends is close. There is also a lot of other direct and indirect, experimental and laboratory evidence about this relationship. This knowledge can be useful for minimizing inspection, predicting new locations for inspection, predicting the location with the highest FAC rate for a given piping component, e.g., feeder element, and determining what components or feeders and to what extent they should be replaced. It applies also to heat exchangers and steam generators. The objective of this paper is to examine the relationship between FAC rate and local flow parameters. For FAC, the most important flow parameter is mass transfer coefficient. The mass transfer coefficient describes the intensity of the transport of corrosion products from the oxide-water interface into the bulk water. Therefore, this parameter can be used for predicting the local distribution of FAC rate. It could also be used in planning experiments because time-varying surface roughness can explain the time-dependence of FAC rates. The paper presents plant and laboratory evidence about the relationship. In addition, it shows correlations for mass transfer coefficient in components that are highly susceptible to FAC. The role of surface roughness, wall shear stress, and local turbulence is also discussed. (author)

  17. Functionalized granular activated carbon and surface complexation with chromates and bi-chromates in wastewater

    Energy Technology Data Exchange (ETDEWEB)

    Singha, Somdutta; Sarkar, Ujjaini, E-mail: usarkar@chemical.jdvu.ac.in; Luharuka, Pallavi

    2013-03-01

    Cr(VI) is present in the aqueous medium as chromate (CrO{sub 4}{sup 2−}) and bi-chromate (HCrO{sub 4}{sup −}). Functionalized granular activated carbons (FACs) are used as adsorbents in the treatment of wastewaters containing hexavalent chromium. The FACs are prepared by chemical modifications of granular activated carbons (GACs) using functionalizing agents like HNO{sub 3}, HCl and HF. The Brunauer, Emmett and Teller surface areas of FAC-HCl (693.5 m{sup 2}/g), FAC-HNO{sub 3} (648.8 m{sup 2}/g) and FAC-HF (726.2 m{sup 2}/g) are comparable to the GAC (777.7 m{sup 2}/g). But, the adsorption capacity of each of the FAC-HNO{sub 3}, FAC-HCl and FAC-HF is found to be higher than the GAC. The functional groups play an important role in the adsorption process and pH has practically no role in this specific case. The FACs have hydrophilic protonated external surfaces in particular, along with the functional surface sites capable to make complexes with the CrO{sub 4}{sup 2−} and HCrO{sub 4}{sup −} present. Surface complex formation is maximized in the order FAC-HNO{sub 3} > FAC-HF > FAC-HCl, in proportion to the total surface acidity. This is also confirmed by the well-known pseudo second-order kinetic model. Physi-sorption equilibrium isotherms are parameterized by using standard Freundlich and Langmuir models. Langmuir fits better. The formation of surface complexes with the functional groups and hexavalent chromium is also revealed in the images of field emission scanning electron micrograph; energy dispersive X-ray spectroscopy and Fourier transform infrared spectroscopy analysis after adsorption. The intra-particle diffusion is not the only rate-controlling factor. The Boyd's film diffusion model fits very well with R{sup 2} as high as 98.1% for FAC-HNO{sub 3}. This result demonstrates that the functionalization of the GAC by acid treatments would increase the diffusion rate, predominantly with a boundary layer diffusion effect. - Highlights: ► Physico

  18. Effect of water chemistry on flow accelerated corrosion rate of carbon steel measured by on-line corrosion-monitoring system

    International Nuclear Information System (INIS)

    Fujiwara, K.; Domae, M.; Yoneda, K.; Inada, F.

    2010-01-01

    Flow Accelerated Corrosion (FAC) of carbon steel is one of the most important subjects in coolant systems of power plants. FAC is influenced by material, flow condition, temperature, and water chemistry. Iron and chromium solubility should be the most effective factor to determine the effect of water chemistry on the FAC. It is very important to evaluate the correlation between the solubility and the FAC rate of the carbon steel. In the present study, the effects of pH and Cr concentration of material on the FAC rate of carbon steel were evaluated by using high temperature loop equipment with on-line corrosion-monitoring system. Effect of dissolved oxygen concentration at pH 7 was also evaluated. The experimental FAC rates were compared with the calculation result, which was obtained from a FAC model developed previously by the authors' group. The tube specimens made of STPT 480 carbon steel were used for the FAC tests. The Cr concentration of STPT 480 was specially adjusted to 0.001 and 0.08 %. The inner diameters of the tubes were 1.6, 2.4, and 3.2 mm. The solutions were fed to the specimens with the flow rate of 1.5 l/min. The temperature of the solution at the specimen was controlled at 140 o C. Test solutions were demineralized water or NH 3 solutions of pH 8.0, 9.2, and 10.0. The increase in pH more than 9 decreased the FAC rates of both 0.001 and 0.08 % Cr specimens at 140 o C. Increase of the Cr concentration of the material decreased the FAC rate in the solution of pH 7.0, 8.0, 9.2, and 10.0. The FAC model reproduced well dependence of the experimental FAC behavior on water chemistry. It was confirmed that effect of pH and Cr concentration of material on the FAC rate were closely related to the solubility and diffusion of iron and chromium. (author)

  19. The Payun-Matru lava field: a source of analogues for Martian long lava flows

    Science.gov (United States)

    Giacomini, L.; Pasquarè, G.; Massironi, M.; Frigeri, A.; Bistacchi, A.; Frederico, C.

    2007-08-01

    'Accademia dei Lincei, 9, 16 (3), 127-135.[2]Pasquaré G., Bistacchi A., Francalanci L.. Gigantic self-confined pahoehoe inflated lava flows in Argentina. Submitted to Terra Nova. [3]Self, S., Keszthelyi, L., Thordarson, Th., 1998. The Importance of Pahoehoe. Annual Review of Earth and Planetary Science, 26, 81-110. [4]Anderson T., 1910. The volcano of Matavanu in Savaii. Geological Society of London Quarterly Journal, 66, 621-639. [5] Walker, G.P.L., 1991. Structure and origin by injection of lava under surface crust, of tumuli, "lava rises", "lava rise pits", and "lava inflation clefts" in Hawaii. Bulletin of Volcanology, 53, 546-558. [6] Hon, K, Kauahikaua, J., Denlinger, R., Mackay, K., 1994. Emplacement and inflation of pahoehoe sheet flows: Observations and measurements of active lava flows on Kilauea Volcano, Hawaii. Geological Society of America Bulletin, 106, 351-370. [7] Llambias, E., 1966. Geología y petrográfica del Volcán Payún-Matru. Acta Geológica Lill., VIII: 265-310. Instituto Lillo, Universidad Nacional Tucumán. Tucumán. [8] Zimbelman, J. R., 1998. Emplacement of long lava flows on planetary surface. J. Geophys. Res., 103, 27503- 27516. [9] Smith, D. E. et al., 1999. The global topography of Mars and implications for surface evolution. Science, 284, 1495-1503. [10] Glaze L.S., Anderson S.W., Stofan E.R., Baloga S., Smrekar S. E, 2005. Statistical distribution of tumuli on pahoehoe flow surfaces: analysis of examples in Hawaii and Iceland and potential application to lava flows on Mars. Journal of Geophysical Research, v. 110, B08202, doc: 10.1029/2004JB003564. [11] MacDonald, 1972. Volcanoes. Prentice-Hall Inc., Englewood Cliffs. 510 pp.

  20. Pipe degradation investigations for optimization of flow-accelerated corrosion inspection location selection

    International Nuclear Information System (INIS)

    Chandra, S.; Habicht, P.; Chexal, B.; Mahini, R.; McBrine, W.; Esselman, T.; Horowitz, J.

    1995-01-01

    A large amount of piping in a typical nuclear power plant is susceptible to Flow-Accelerated Corrosion (FAC) wall thinning to varying degrees. A typical PAC monitoring program includes the wall thickness measurement of a select number of components in order to judge the structural integrity of entire systems. In order to appropriately allocate resources and maintain an adequate FAC program, it is necessary to optimize the selection of components for inspection by focusing on those components which provide the best indication of system susceptibility to FAC. A better understanding of system FAC predictability and the types of FAC damage encountered can provide some of the insight needed to better focus and optimize the inspection plan for an upcoming refueling outage. Laboratory examination of FAC damaged components removed from service at Northeast Utilities' (NU) nuclear power plants provides a better understanding of the damage mechanisms involved and contributing causes. Selected results of this ongoing study are presented with specific conclusions which will help NU to better focus inspections and thus optimize the ongoing FAC inspection program

  1. Effects of alloy composition and flow condition on the flow accelerated corrosion in neutral water condition

    International Nuclear Information System (INIS)

    Satoh, Tomonori; Ugachi, Hirokazu; Tsukada, Takashi; Uchida, Shunsuke

    2008-01-01

    The major mechanism of Flow accelerated corrosion (FAC) is the dissolution of the protective oxide on carbon steel, which is enhanced by mass transfer and erosion under high flow velocity conditions. In this study, the effects of alloy composition and flow velocity on FAC of carbon steel were evaluated by measuring FAC rate of tube type carbon steel specimens in the neutral water condition at 150degC. Obtained results are summarized in follows. 1) High FAC rate was depended upon the v 1.2 in the tube type specimen made of the standard alloy. 2) FAC was mitigated for the carbon steel with more than 0.03% of Cr content. 3) FAC rate decreased as Ni content increased in more than 0.1% of Ni content. 4) The difference in chemical composition of oxide film between Ni added carbon steel and Cr added one was confirmed. The hematite rich oxide was observed for Ni added carbon steel. 5) The effects of Cu on FAC rate was not observed up to 0.1% of Cu content. (author)

  2. Comparison of flow cytometry and immunohistochemistry in non-radioisotopic murine lymph node assay using bromodeoxyuridine.

    Science.gov (United States)

    Jung, Kyoung-Mi; Bae, Il-Hong; Kim, Bae-Hwan; Kim, Wang-Ki; Chung, Jin-Ho; Park, Young-Ho; Lim, Kyung-Min

    2010-02-01

    Non-radioisotopic local lymph node assay (LLNA) employing 5-bromo-2'-deoxyuridine (BrdU) with flow cytometry (FACS) or immunohistochemistry (IHC) is gaining attention due to a regulatory issue of using radioisotope, (3)H-thymidine, in vivo in traditional LLNA. In this study, to compare the performance of these non-radioisotopic endpoints, 7 chemicals with known sensitizing potencies were examined in LLNA. Mice were topically treated with chemicals or vehicle on both ears for 3 days. After intraperitoneal injection of BrdU, bilateral lymph nodes were isolated separately and undergone respectively, FACS or IHC to determine BrdU incorporated lymph node cells (LNCs). Weight and histology of treated ears were also examined to evaluate chemical-induced edema and irritation. Both FACS and IHC could successively identify the skin sensitizers from non-sensitizers. Comparison of FACS and IHC with traditional LLNA revealed that FACS has a higher sensitivity although both assays produced comparable sensitivity and performance to traditional LLNA. In conclusion, non-radioisotopic LLNA using FACS and IHC can successfully detect sensitizers with a good correlation to traditional LLNA. Notably, FACS showed almost equivalent sensitivity and accuracy to traditional LLNA. 2009 Elsevier Ireland Ltd. All rights reserved.

  3. Correlation of flow accelerated corrosion rate with iron solubility

    International Nuclear Information System (INIS)

    Fujiwara, K.; Domae, M.; Yoneda, K.; Inada, F.; Ohira, T.; Hisamune, K.; Takiguchi, H.

    2009-01-01

    Flow Accelerated Corrosion (FAC) of carbon steel is one of the most important subjects in coolant systems of power plants. FAC is influenced by material, flow condition, temperature, and water chemistry. It is considered that solubility is the most important factor to determine the effect of water chemistry on FAC. In the present study, effect of specific oxide on FAC rate was studied from the thermodynamic solubility of iron. The effects of temperature and pH on the iron solubility were evaluated by taking into consideration hydrolysis reactions of ferrous iron, dissolution equilibria of Fe 3 O 4 , FeO, and Fe(OH) 2 , and charge balance. The correlation between the iron solubility and FAC behavior was evaluated by using the normalized mass transfer coefficient. It is clarified that the product of iron solubility equilibrated with Fe 3 O 4 and normalized mass transfer coefficient can explain the temperature and pH dependence of FAC. These results indicate presence of magnetite on the surface of carbon steel. Diffusion of iron from the saturated layer determines the FAC rate from water chemistry aspect. (author)

  4. Report on results of audit related to charges for wholesale electric service by New England Power Company under the Fuel-Adjustment Clause filed with the Federal Power Commission

    Energy Technology Data Exchange (ETDEWEB)

    1975-12-01

    During the 39-month period beginning in April 1972 and ending in June 1975, NEPCO, through monthly fuel-adjustment clause (FAC) billings, charged its wholesale customers and certain other customers about $316.1 million. The audit disclosed that in computing FAC charges applicable to its wholesale customers, NEPCO included certain costs not eligible for inclusion in FAC billings under the applicable FAC on file with the Commission. As a result, for the 39-month period ending in June 1975, wholesale customers were overbilled through the FAC an estimated $800,000. The fact that certain costs were not eligible for inclusion under the FAC were not construed as meaning that the costs may not be proper for consideration in establishing NEPCO's cost of service for rate purposes, apart from the FAC. The staff concluded that in all other respects NEPCO had properly billed its customers for charges in the cost of fossil fuel in accordance with its filed fuel-adjustment clause.

  5. Diffusion behavior of anion in hardened low-heat portland cement paste containing fly ash. Dependence of effective diffusion coefficient on pore structure

    International Nuclear Information System (INIS)

    Chida, Taiji; Yoshida, Takahiro

    2012-01-01

    In the sub-surface disposal system, the closely packed concrete layer is expected the low diffusivity to retard the migration of radionuclides. Low-heat portland cement containing 30 wt% fly ash (FAC) is a candidate cement material for the construction of sub-surface repository because of its high dense structure and its resistance to cracking. Previously, we reported that FAC has lower diffusivity than Ordinary Portland Cement (OPC) for acetic acid and iodine. However, the mechanism for low diffusivity of FAC was not clear. In this study, the diffusion of multiple trace ions (chlorine, bromine and iodine) in hardened cement pastes was examined by through-diffusion experiments. The effective diffusion coefficients, D e , of the trace ions for hardened OPC cement pastes were on the order of 10 -12 m 2 s -1 for trace ions, and D e for hardened FAC cement pastes were on the order of 10 -13 m 2 s -1 for chlorine, 10 -14 m 2 s -1 for bromine and 10 -15 m 2 s -1 for iodine. Additionally, the pore size distribution and porosity of FAC changed to more closely packed structure for 13 months by the pozzolanic reaction, and the pore size distribution of FAC (mainly 3-10 nm) were an order of magnitude smaller than that of OPC. These results suggest that the low diffusivity of FAC is based on the continuous change in the pore structure and the nano-scale pore size retarding the migration of trace ions. (author)

  6. Effect of flow conditions on flow accelerated corrosion in pipe bends

    International Nuclear Information System (INIS)

    Mazhar, H.; Ching, C.Y.

    2015-01-01

    Flow Accelerated Corrosion (FAC) in piping systems is a safety and reliability problem in the nuclear industry. In this study, the pipe wall thinning rates and development of surface roughness in pipe bends are compared for single phase and two phase annular flow conditions. The FAC rates were measured using the dissolution of test sections cast from gypsum in water with a Schmidt number of 1280. The change in location and levels of maximum FAC under single phase and two phase flow conditions are examined. The comparison of the relative roughness indicates a higher effect for the surface roughness in single phase flow than in two phase flow. (author)

  7. Flow-accelerated corrosion in nuclear power plants: application of CHECWORKS at Darlington

    International Nuclear Information System (INIS)

    Schefski, C.; Pietralik, J.; Dyke, T.; Lewis, M.

    1995-01-01

    CHECWORKS, a comprehensive software package for managing Flow-Accelerated Corrosion (FAC) concerns in the secondary side, was applied to supplement and improve the existing FAC program at Darlington NGS. The database created for the station contains the Heat Balance Diagram, susceptible-to FAC secondary side systems, ultrasonic inspection data, drawings and pictures. The distribution of hot pH and oxygen within the secondary side was calculated and components were ranked by wear rate. The predicted wear rates are relatively small, mainly because of the favourable water chemistry. It was demonstrated that the package is a very useful tool complementing the existing In-Service Inspection program. (author)

  8. Rhenium and technetium: application of organometallic rhenium and technetium complexes in radiopharmacy. Evaluation of optimal anchor groups

    International Nuclear Information System (INIS)

    Alberto, R.; Schibli, R.; Egli, A.; Schaffland, A.; Rattat, D.; Mueller, J.; Iftimia, M.; Berke, H.; Kaden, T.A.; Abram, U.

    1997-01-01

    The coordinative properties of the '[fac-M(CO) 3 ] + ' moiety (M= 188 Re, Re, 99 Tc and 99m Tc) have been investigated in water and organic solvents in order to evaluate the anchor group attached to antibodies, small peptides and biologically active molecules. The preparation of [M(OH 2 ) 3 (CO) 3 ] + has been improved in a way that this complex can be prepared from a Kit formulation. The '[fac-M(CO) 3 ] + ' has been transformed to the '[fac-M(NO)(CO) 2 ] 2+ ' moiety to achieve higher direct labelling yields and faster incorporation kinetics. (author) 5 figs

  9. On the cause of IMF By related mid- and low latitude magnetic disturbances

    DEFF Research Database (Denmark)

    Vennerstrøm, Susanne; Christiansen, Freddy; Olsen, Nils

    2007-01-01

    An analysis of the effect of the IMF By on near-Earth low and mid-latitude magnetic disturbances is presented. In particular the contribution from field-aligned currents ( FACs) connected to the polar regions is investigated. Based on statistically determined high-latitude FAC patterns for various...... that the long-distance effect of the high-latitude FACs constitute the major source to IMF By and B-z related magnetic east-west disturbances at mid-and low latitudes....

  10. Relationship between PC index and magnetospheric field-aligned currents measured by Swarm satellites

    DEFF Research Database (Denmark)

    Troshichev, О.; Sormakov, D.; Behlke, R.

    2018-01-01

    Abstract The relationship between the magnetospheric field-aligned currents (FAC) monitored by the Swarm satellites and the magnetic activity PC index (which is a proxy of the solar wind energy incoming into the magnetosphere) is examined. It is shown that current intensities measured in the R1...... between the PC index and the intensity of field-aligned currents in the R1 dawn and dusk layers: increase of FAC intensity in the course of substorm development is accompanied by increasing the PC index values. Correlation between PC and FAC intensities in the R2 dawn and dusk layers is also observed...

  11. Modern processing technologies and food quality. 18th Food Technology Days '97 dedicated to prof. F. Bitenc

    International Nuclear Information System (INIS)

    Zlender, Bozidar; Gasperlin, Lea; Hocevar, Ivica; Slemenik, Barbka; Hocevar, Polona

    1997-01-01

    Modern processing technologies and food quality. Proceedings of thematic survey of topics in food science and technology and nutrition for postgraduate students, Ljubljana Univ. (Slovenia). Biotechnical Fac., Food Science and Technology Dept

  12. Reference: 594 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available nction mutant hig1-1 contained low levels of glucosinolates. Overexpression of the related transcription fac...the mutant chemotype along with a severe high-auxin growth phenotype. Overexpression of MYB122, another clos

  13. Colostomy

    Science.gov (United States)

    ... the abdomen, such as perforated diverticulitis or an abscess . Injury to the colon or rectum (for example, ... Wechter, MD, FACS, General Surgery practice specializing in breast cancer, Virginia Mason Medical Center, Seattle, WA. Also ...

  14. Gastrectomy

    Science.gov (United States)

    ... to the intestine which can cause infection or abscess The connection to the intestine narrows, causing blockage ... Wechter, MD, FACS, general surgery practice specializing in breast cancer, Virginia Mason Medical Center, Seattle, WA. Also ...

  15. Anoscopy

    Science.gov (United States)

    ... What Abnormal Results Mean Abnormal results may include: Abscess Fissures Foreign object in the anus Hemorrhoids Infection ... Wechter, MD, FACS, general surgery practice specializing in breast cancer, Virginia Mason Medical Center, Seattle, WA. Also ...

  16. Total abdominal colectomy

    Science.gov (United States)

    ... the rectum. This can cause an infection or abscess. Scarring of the connection between the small intestine ... Wechter, MD, FACS, general surgery practice specializing in breast cancer, Virginia Mason Medical Center, Seattle, WA. Also ...

  17. Annals of African Surgery July 2011 07.12.2011.indd

    African Journals Online (AJOL)

    andrew

    Orth), Schenck R2, MD, FACS Affiliation: 1-Department of Orthopaedics, Makerere University, Kampala,. Uganda /Orthopaedic Surgeon, Orthopaedic Rehabilitation Unit, PCEA Kikuyu Hospital, Kikuyu Kenya 2- Department of Plastic Surgery, ...

  18. Physiological characterisation of acuB deletion in Aspergillus niger

    DEFF Research Database (Denmark)

    Meijer, Susan Lisette; De Jongh, Willem Adriaan; Olsson, Lisbeth

    2009-01-01

    The acuB gene of Aspergillus niger is an ortholog of facB in Aspergillus nidulans. Under carbon-repression conditions, facB is repressed, thereby preventing acetate metabolism when the repressing carbon source is present. Even though facB is reported to be repressed directly by CreA, it is believed...... that a basal level of FacB activity exists under glucose-repressive conditions. In the present study, the effect of deletion of acuB on the physiology of A. niger was assessed. Differences in organic acid and acetate production, enzyme activities and extracellular amino and non-amino organic acid production...... were determined under glucose-repressing and -derepressing conditions. Furthermore, consumption of alternative carbon sources (e.g. xylose, citrate, lactate and succinate) was investigated. It was shown that AcuB has pleiotropic effects on the physiology of A. niger. The results indicate that metabolic...

  19. Gas Stations, US, 2010, NAVTEQ

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Gas_Stations dataset is derived from the Navteq 'AUTOSVC' SDC layer (FAC_TYPE=5540) and contains gas stations and petrol stations. This NAVTEQ dataset is...

  20. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Find a Surgeon Patients and Family Contact My Profile Shop ( 0 ) Cart Donate Become a Member Join ... Discount Programs FACS Resources Career Connection Update Your Profile Member Communities 2018 Initiates Leadership Opportunities Leadership Opportunities ...

  1. Wall thinning of piping in power plants

    International Nuclear Information System (INIS)

    Ohta, Joji; Inada, Fumio; Morita, Ryo; Kawai, Noboru; Yoneda, Kimitoshi

    2005-01-01

    Major mechanisms causing wall thinning of piping in power plants are flow accelerated corrosion (FAC), cavitation erosion and droplet erosion. Their fundamental aspects are reviewed on the basis of literature data. FAC is chemical process and it is affected by hydrodynamic factors, temperature, pH, dissolved oxygen concentration and chemical composition of materials. On the other hand, cavitation erosion and droplet erosion are mechanical process and they are mainly affected by hydrodynamic factors and mechanical properties of materials. Evaluation codes for FAC and mitigation methods of FAC and the erosion are also described. Wall thinning of piping is one of public concerns after an accident of a pipe failure at Mihama Nuclear Power Plant Unit 3, Kansai Electric Power Co., Inc., in August 2004. This paper gives comprehensive understanding of the wall thinning mechanism. (author)

  2. Living Beyond Breast Cancer

    Science.gov (United States)

    ... ACTH CAF CMF FAC TAC TC TCH TH THP Radiation Therapy Whole Breast Radiation Partial Breast Radiation ... Basics Treatments and Your Bone Health Bone Health Tests Improving Bone Health Medicines To Protect Bones Diet, ...

  3. Guide to Understanding Triple-Negative Breast Cancer

    Science.gov (United States)

    ... ACTH CAF CMF FAC TAC TC TCH TH THP Radiation Therapy Whole Breast Radiation Partial Breast Radiation ... Basics Treatments and Your Bone Health Bone Health Tests Improving Bone Health Medicines To Protect Bones Diet, ...

  4. Guide to Understanding Lymphedema

    Science.gov (United States)

    ... ACTH CAF CMF FAC TAC TC TCH TH THP Radiation Therapy Whole Breast Radiation Partial Breast Radiation ... Basics Treatments and Your Bone Health Bone Health Tests Improving Bone Health Medicines To Protect Bones Diet, ...

  5. Study on Increasing High Temperature pH(t) to Reduce Iron Corrosion Products

    International Nuclear Information System (INIS)

    Shin, Dong Man; Hur, Nam Yong; Kim, Waang Bae

    2011-01-01

    The transportation and deposition of iron corrosion products are important elements that affect both the steam generator (SG) integrity and secondary system in pressurized water reactor (PWR) nuclear power plants. Most of iron corrosion products are generated on carbon steel materials due to flow accelerated corrosion (FAC). The several parameters like water chemistry, temperature, hydrodynamic, and steel composition affect FAC. It is well established that the at-temperature pH of the deaerated water system has a first order effect on the FAC rate of carbon steels through nuclear industry researches. In order to reduce transportation and deposition of iron corrosion products, increasing pH(t) tests were applied on secondary system of A, B units. Increasing pH(t) successfully reduced flow accelerated corrosion. The effect of increasing pH(t) to inhibit FAC was identified through the experiment and pH(t) evaluation in this paper

  6. Erosion and erosion-corrosion

    International Nuclear Information System (INIS)

    Isomoto, Yoshinori

    2008-01-01

    It is very difficult to interpret the technical term of erosion-corrosion' which is sometimes encountered in piping systems of power plants, because of complicated mechanisms and several confusing definitions of erosion-corrosion phenomena. 'FAC (flow accelerated corrosion)' is recently introduced as wall thinning of materials in power plant systems, as a representative of 'erosion-corrosion'. FAC is, however, not necessarily well understood and compared with erosion-corrosion. This paper describes firstly the origin, definition and fundamental understandings of erosion and erosion-corrosion, in order to reconsider and reconfirm the phenomena of erosion, erosion-corrosion and FAC. Next, typical mapping of erosion, corrosion, erosion-corrosion and FAC are introduced in flow velocity and environmental corrosiveness axes. The concept of damage rate in erosion-corrosion is finally discussed, connecting dissolution rate, mass transfer of metal ions in a metal oxide film and film growth. (author)

  7. Breast lift

    Science.gov (United States)

    ... and areola may be moved. Sometimes, women have breast augmentation (enlargement with implants) when they have a breast lift. Why the ... MD, FACS, general surgery practice specializing in breast cancer, Virginia Mason Medical Center, Seattle, WA. Also reviewed ...

  8. Apoptosis and Tumor Progressionin Prostate Cancer

    National Research Council Canada - National Science Library

    Tenniswood, Martin P

    2005-01-01

    ... (as measured by BrdU incorporation) and apoptosis as measured by TUNEL staining. We have standardized an efficient methodologies for isolating cells from primary tumors expressing REP by fluorescence activated cell sorting (FACS...

  9. Perceptions and knowledge about prostate cancer and attitudes ...

    African Journals Online (AJOL)

    B. Yeboah-Asiamah

    2017-06-29

    Jun 29, 2017 ... and previous family history of the disease are known risk fac- tors [6,7]. .... tiple regression) models considered variables from the unadjusted analysis ..... et al. Quantifying the role of PSA screening in the US prostate cancer.

  10. 75 FR 17913 - Maintenance and Vegetation Management Along Existing Western Area Power Administration...

    Science.gov (United States)

    2010-04-08

    ... Maintenance and Vegetation Management Along Existing Western Area Power Administration Transmission Line... Corporation's mandatory vegetation management and maintenance standards (FAC-003-1) in accordance with section... Service) authorizations or issuing new authorizations to accommodate Western's vegetation management...

  11. Your Lung Operation: After Your Operation

    Medline Plus

    Full Text Available ... Find a Surgeon Patients and Family Contact My Profile Shop ( 0 ) Cart Donate Become a Member Join ... Discount Programs FACS Resources Career Connection Update Your Profile Member Communities 2018 Initiates Leadership Opportunities Leadership Opportunities ...

  12. Breast reduction (mammoplasty) - slideshow

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/presentations/100189.htm Breast reduction (mammoplasty) - series—Indications To use the sharing features ... Lickstein, MD, FACS, specializing in cosmetic and reconstructive plastic surgery, Palm Beach Gardens, FL. Review provided by ...

  13. Effect of a nano-sized TiC particle addition on the flow-assisted corrosion resistance of SA 106B carbon steel

    Science.gov (United States)

    Park, Jin-Ju; Park, Eun-Kwang; Lee, Gyoung-Ja; Rhee, Chang-Kyu; Lee, Min-Ku

    2017-09-01

    Carbon steel with dispersed nano-sized TiC ceramic particles was fabricated by the ex-situ introduction of the particles into the melt, with the flow-assisted corrosion (FAC) resistance then investigated in the presence and absence of TiC nanoparticles using a once-through type of FAC loop test. From the potentiodynamic polarization curves, the current density at any given anodic potential was decreased and the open-circuit potential was increased by the addition of TiC nanoparticles. In addition, when the nano-sized TiC particles were added, the FAC rate was 1.38 times lower than that of carbon steel without TiC nanoparticles, indicating an improvement of the FAC resistance due to the homogeneous distribution of the TiC reinforcing nanoparticles.

  14. Public-private partnership oversight : how FHWA reviews P3s.

    Science.gov (United States)

    2015-01-01

    A growing number of State and local transportation agencies are considering the use of public-private : partnerships (P3s), in which a private entity is involved in designing, financing, constructing, operating, : and maintaining a transportation fac...

  15. The effect of HCV serological status on Doxorubicin based ...

    African Journals Online (AJOL)

    Karim Yousri Welaya

    2014-09-10

    Sep 10, 2014 ... Pretreatment evaluation included serological testing for HCV. FAC Adjuvant ... National Cancer Institute; IRB, Institutional Research Board; LVEF, ..... Mild Skin changes, including skin discoloration and nail changes, not ...

  16. Foeto-maternal outcome of HIV-positive pregnant women on Highly ...

    African Journals Online (AJOL)

    McRoy

    2014-12-31

    Dec 31, 2014 ... Strengthening the use of HAART may maintain zero vertical transmission among other ... HIV acquired the infection through mother-to- child transmission ... Absolute counts of CD4 cells were measured using the FACS Count ...

  17. 76 FR 66912 - Marine Protected Areas Federal Advisory Committee; Public Meeting

    Science.gov (United States)

    2011-10-28

    ... Protected Areas Federal Advisory Committee (Committee) in New Orleans, Louisiana. DATES: The meeting will be... Yeager, Designated Federal Officer, MPA FAC, National Marine Protected Areas Center, 1305 East West... DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration (NOAA) Marine Protected...

  18. 78 FR 67338 - Marine Protected Areas Federal Advisory Committee; Public Meeting

    Science.gov (United States)

    2013-11-12

    ... DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration Marine Protected Areas... the Marine Protected Areas Federal Advisory Committee (Committee). The web conference calls are open..., MPA FAC, National Marine Protected Areas Center, 1305 East West Highway, Silver Spring, Maryland 20910...

  19. Isolating dividing neural and brain tumour cells for gene expression profiling

    Czech Academy of Sciences Publication Activity Database

    Endaya, B.; Cavanagh, B.; Alowaidi, F.; Walker, T.; de Pennington, N.; Ng, J.-M.; Lam, P.Y.P.; Mackay-Sim, A.; Neužil, Jiří; Meedeniya, A.C.B.

    2016-01-01

    Roč. 257, JAN 15 2016 (2016), s. 121-133 ISSN 0165-0270 Institutional support: RVO:86652036 Keywords : Cell division * Click chemistry * FACS Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 2.554, year: 2016

  20. Scattering of Tone Bursts from Spherical Shells: Computations Based on Fourier Transform Method.

    Science.gov (United States)

    1991-08-30

    0 SALP =0. 0 N1=0 SUM=0. 0 CALL STVAL(X,X1,X2 ,ALPN, BETN,CBN1, BN1,SNN1,RH,XSN,X2S,XCS) 20 CONTINUE CE-N2= PCB(N+3)/PCB(N+2) Q=FLOAT (N+1) 88 ANUM-(Q...BETN*BETN1)) FAC=XSIGN* (2. 0*Q-1. 0) SALP = SALP +FAC*ALPN SBET=SBET+FAC* BETN ALPN=ALPN1 BETN=BETN1 SUM=SUM+ADD IF ((ABS(ADD/SUM)).LT.1.OE-8) GO TO 90...J=O N=N±1 XSIGN=-XSIGN GO TO 20 90 J=J+1 IF (J.EQ.5) GO TO 100 N=N+1 XSIGN=-XSIGN GO TO 20 100 YP=(-4.0/(X**2))*SUM FAC=-XSIGN* (2. 0*Q+1.0) SALP = SALP

  1. 77 FR 75780 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-64; Small Entity Compliance Guide

    Science.gov (United States)

    2012-12-21

    ... analyst whose name appears in the table below in relation to the FAR case. Please cite FAC 2005-64 and the... predecessor contractor and its subcontractors a right of first refusal of employment for positions for which...

  2. Collision strengths for transitions in Ni XIX

    Indian Academy of Sciences (India)

    4l configurations of Ni XIX, for which flexible atomic code. (FAC) has been ... atomic data (namely energy levels, radiative rates, collision strengths, excitation rates, etc.) ... Zhang and Sampson, who adopted the Coulomb–Born-exchange.

  3. Waste Management Policy Framework to Mitigate Terrorist Intrusion Activities

    International Nuclear Information System (INIS)

    Redus, Kenneth S.

    2003-01-01

    A policy-directed framework is developed to support US Department of Energy (DOE) counterterrorism efforts, specifically terrorist intrusion activities that affect of Environmental Management (EM) programs. The framework is called the Security Effectiveness and Resource Allocation Definition Forecasting and Control System (SERAD-FACS). Use of SERAD-FACS allows trade-offs between resources, technologies, risk, and Research and Development (R and D) efforts to mitigate such intrusion attempts. Core to SERAD-FACS is (1) the understanding the perspectives and time horizons of key decisionmakers and organizations, (2) a determination of site vulnerabilities and accessibilities, and (3) quantifying the measures that describe the risk associated with a compromise of EM assets. The innovative utility of SERAD-FACS is illustrated for three integrated waste management and security strategies. EM program risks, time delays, and security for effectiveness are examined to demonstrate the significant cost and schedule impact terrorist activities can have on cleanup efforts in the DOE complex

  4. Flame spread over inclined electrical wires with AC electric fields

    KAUST Repository

    Lim, Seung J.; Park, Sun H.; Park, Jeong; Fujita, Osamu; Keel, Sang I.; Chung, Suk-Ho

    2017-01-01

    Flame spread over polyethylene-insulated electrical wires was studied experimentally with applied alternating current (AC) by varying the inclination angle (θ), applied voltage (VAC), and frequency (fAC). For the baseline case with no electric field

  5. The National Wetland Plant List

    Science.gov (United States)

    2012-10-01

    Slippery-Burr Cordia bellonis Urban FACW Serpentine Manjack Cordia borinquensis Urban FACW Muneco Cordia dichotoma G. Forst. UPL...FACU Fragrant Manjack Cordia sebestena L. FAC UPL Large-Leaf Geigertree Cordia subcordata Lam. FACU Kou Cordia wagneriorum

  6. 77 FR 25164 - Revision to Transmission Vegetation Management Reliability Standard; Notice Inviting Comments on...

    Science.gov (United States)

    2012-04-27

    ... mathematics and documentation of the technical justification behind the application of the Gallet equation and... application in NERC- approved Reliability Standard FAC-003-2 reasonable to address the minimum distance...

  7. The role of trees in urban stormwater management

    Science.gov (United States)

    Urban impervious surfaces convert precipitation to stormwater runoff, which causes water quality and quantity problems. While traditional stormwater management has relied on gray infrastructure such as piped conveyances to collect and convey stormwater to wastewater treatment fac...

  8. Teen Brain: Still Under Construction

    Science.gov (United States)

    ... report finding that it is a factor in delinquency. Adequate sleep is central to physical and emotional ... other fac- tors, among them, inborn traits, personal history, family, friends, community, and culture.

  9. Remarkable evolutionary conservation of SOX14 orthologues

    Indian Academy of Sciences (India)

    transcriptional factors and architectural components of chro- matin (Pevny and .... F7, coagulation fac- tor VII (serum prothrombin conversion accelerator); LAMP1, .... of RNA into protein nor in RNA stability, but in production, or in transcription ...

  10. Treatment of a diamond mine's slimes tailings

    African Journals Online (AJOL)

    2006-07-21

    Jul 21, 2006 ... Most of the commercial settling reagents (for coagulation .... a larger body of water subjected to all the environmental fac- tors. The objectives ... the macro- and micro-components making up the gypsum), ..... Company report.

  11. EFFECTIVENESS OF SECRETOLYTIC THERAPY IN REHABILITATION PROGRAM IN FREQUENTLY AILING CHILDREN

    Directory of Open Access Journals (Sweden)

    V.V. Kiselev

    2008-01-01

    Full Text Available A problem of rehabilitation of frequently ailing children (FAC is one of the actual problems in pediatrics. Disorders of mucosal immunity, depending on different factors including the state of mucociliary transport, play important role in formation of FAC group including patients with recurrent episodes of obstructive bronchitis. Morphological and functional unity of mucous tunic of respiratory tract allows determining the state of mucociliary clearance and effectiveness of secretolytic therapy by the state of mucosal tunic of nose and nasopharynx (it is the most accessible mucosal tunic for the objective examination. Specified rates of time of mucociliary transport in different groups of FAC are presented in this article. An effectiveness of mucoregulatory medication ambroxol in complex treatment of FAC with adenoids and recurrent episodes of obstructive bronchitis, and advisability of its prolonged (14–18 days use for the recovery of disturbed system of mucociliary transport were described in this article.Key words: frequently ailing children, somatotype, mucociliary clearance, treatment.

  12. Ostomy Home Skills Program

    Medline Plus

    Full Text Available ... Associate Fellows Residents Medical Students Affiliate Members ACS Insurance Programs ACS Discount Programs FACS Resources Career Connection ... and Awards Overview Scholarships, Fellowships, and Awards Overview Health Policy Scholarships Scholarships for International Surgeons Research Scholarships ...

  13. Your Lung Operation: After Your Operation

    Medline Plus

    Full Text Available ... Associate Fellows Residents Medical Students Affiliate Members ACS Insurance Programs ACS Discount Programs FACS Resources Career Connection ... and Awards Overview Scholarships, Fellowships, and Awards Overview Health Policy Scholarships Scholarships for International Surgeons Research Scholarships ...

  14. Update of the water chemistry effect on the flow-accelerated corrosion rate of carbon steel: influence of hydrazine, boric acid, ammonia, morpholine and ethanolamine

    International Nuclear Information System (INIS)

    Pavageau, E.-M.; De Bouvier, O.; Trevin, S.; Bretelle, J.-L.; Dejoux, L.

    2007-01-01

    The influence of the water chemistry on Flow-Accelerated Corrosion (FAC) affecting carbon steel components has been studied for many years and is relatively well known and taken into account by the models. Nonetheless, experimental studies were conducted in the last few years at EDF on the CIROCO loop in order to check the influence of the water chemistry parameters (hydrazine, boric acid, ammonia, morpholine and ethanolamine) on the FAC rate of carbon steel in one phase flow conditions. The hydrazine impact on the FAC rate was shown to be minor in EDF's chemistry recommendation range, compared to other parameters' effects such as the pH effect. The presence of boric acid in the nominal secondary circuit conditions was negligible. Finally, as expected, the nature of the chemical conditioning (ammonia, morpholine or ethanolamine) did not modify the FAC rate, the influencing chemical variable being the at-temperature pH in one-phase flow conditions. (author)

  15. Human biodistribution and radiation dosimetry of novel PET probes targeting the deoxyribonucleoside salvage pathway

    Energy Technology Data Exchange (ETDEWEB)

    Schwarzenberg, Johannes [David Geffen School of Medicine, University of California, Department of Molecular and Medical Pharmacology, Ahmanson Biological Imaging Division, Los Angeles, CA (United States); Medical University of Vienna, Department of Pediatrics, Vienna (Austria); Radu, Caius G.; Tran, Andrew Q.; Phelps, Michael E.; Satyamurthy, Nagichettiar [David Geffen School of Medicine, University of California, Department of Molecular and Medical Pharmacology, Crump Institute for Molecular Imaging, Los Angeles, CA (United States); Benz, Matthias; Fueger, Barbara; Czernin, Johannes; Schiepers, Christiaan [David Geffen School of Medicine, University of California, Department of Molecular and Medical Pharmacology, Ahmanson Biological Imaging Division, Los Angeles, CA (United States); Witte, Owen N. [David Geffen School of Medicine, University of California, Howard Hughes Medical Institute and Department of Microbiology, Immunology, and Molecular Genetics, Los Angeles, CA (United States)

    2011-04-15

    Deoxycytidine kinase (dCK) is a rate-limiting enzyme in deoxyribonucleoside salvage, a metabolic pathway involved in the production and maintenance of a balanced pool of deoxyribonucleoside triphosphates (dNTPs) for DNA synthesis. dCK phosphorylates and therefore activates nucleoside analogs such as cytarabine, gemcitabine, decitabine, cladribine, and clofarabine that are used routinely in cancer therapy. Imaging probes that target dCK might allow stratifying patients into likely responders and nonresponders with dCK-dependent prodrugs. Here we present the biodistribution and radiation dosimetry of three fluorinated dCK substrates, {sup 18}F-FAC, L-{sup 18}F-FAC, and L-{sup 18}F-FMAC, developed for positron emission tomography (PET) imaging of dCK activity in vivo. PET studies were performed in nine healthy human volunteers, three for each probe. After a transmission scan, the radiopharmaceutical was injected intravenously and three sequential emission scans acquired from the base of the skull to mid-thigh. Regions of interest encompassing visible organs were drawn on the first PET scan and copied to the subsequent scans. Activity in target organs was determined and absorbed dose estimated with OLINDA/EXM. The standardized uptake value was calculated for various organs at different times. Renal excretion was common to all three probes. Bone marrow had higher uptake for L-{sup 18}F-FAC and L-{sup 18}F-FMAC than {sup 18}F-FAC. Prominent liver uptake was seen in L-{sup 18}F-FMAC and L-{sup 18}F-FAC, whereas splenic activity was highest for {sup 18}F-FAC. Muscle uptake was also highest for {sup 18}F-FAC. The critical organ was the bladder wall for all three probes. The effective dose was 0.00524, 0.00755, and 0.00910 mSv/MBq for {sup 18}F-FAC, L-{sup 18}F-FAC, and L-{sup 18}F-FMAC, respectively. The biodistribution of {sup 18}F-FAC, L-{sup 18}F-FAC, and L-{sup 18}F-FMAC in humans reveals similarities and differences. Differences may be explained by different probe

  16. Evaluation of Flow Accelerated Corrosion of Carbon Steel with Rotating Cylinder

    International Nuclear Information System (INIS)

    Park, Tae Jun; Lee, Eun Hee; Kim, Kyung Mo; Kim, Hong Pyo

    2012-01-01

    Flow accelerated corrosion (FAC) of the carbon steel piping in nuclear power plants (NPPs) has been major issue in nuclear industry. Rotating cylinder FAC test facility was designed and fabricated and then performance of the facility was evaluated. The facility is very simple in design and economic in fabrication and can be used in material and chemistry screening test. The facility is equipped with on line monitoring of pH, conductivity, dissolved oxygen(DO), and temperature. Fluid velocity is controlled with rotating speed of the cylinder with a test specimen. FAC test of SA106 Gr. B carbon steel under 4 m/s flow velocity was performed with the rotating cylinder at DO concentration of less than 1 ppb and of 1.3 ppm. Also a corrosion test of the carbon steel at static condition, that is at zero fluid velocity, of test specimen and solution was performed at pH from 8 to 10 for comparison with the FAC data. For corrosion test in static condition, the amount of non adherent corrosion product was almost constant at pH ranging from 8 to 10. But adherent corrosion product decreased with increasing pH. This trend is consistent with decrease of Fe solubility with an increase in pH. For FAC test with rotating cylinder FAC test facility, the amount of non adherent corrosion product was also almost same for both DO concentrations. The rotating cylinder FAC test facility will be further improved by redesigning rotating cylinder and FAC specimen geometry for future work

  17. Effect of sleep deprivation on driving safety in housestaff.

    Science.gov (United States)

    Marcus, C L; Loughlin, G M

    1996-12-01

    Sleep deprivation is known to affect driving safety. Housestaff (HS) are routinely sleep-deprived when on call. We hypothesized that this would affect their driving. We therefore administered questionnaires regarding driving to 70 pediatric HS, who were on call every fourth night, and to 85 faculty members (FAC), who were rarely disturbed at night. HS were questioned about events during their residency, and FAC were questioned about events during the preceding three years. There was an 87% response rate for each group. HS slept 2.7 +/- 0.9 (SD) hours when on call vs 7.2 +/- 0.8 hours when not on call (p < 0.001). 44% of HS had fallen asleep when stopped at a light, vs 12.5% FAC (p < 0.001). 23% of HS had fallen asleep while driving vs. 8% FAC (ns). A total of 49% of HS had fallen asleep at the wheel; 90% of these events occurred post-call. In contrast, only 13% of FAC had fallen asleep at the wheel (p < 0.001). HS had received a total of 25 traffic citations for moving violations vs. 15 for FAC and were involved in 20 motor vehicle accidents vs. 11 for FAC. One traffic citation clearly resulted from HS falling asleep at the wheel vs. none for FAC. We conclude that HS frequently fall asleep when driving post-call. We speculate that current HS work schedules may place some HS at risk for injury to themselves and others. Further study, using prospectively objective measures is indicated.

  18. Influence of BDNF Genotype and Exercise on BDNF Serum Levels and VO2 Max after Acute Exercise and Post Training

    Science.gov (United States)

    2017-07-29

    memory and decision- making) ( termed FAC henceforth) to traditional AFPT (LC). The FAC training incorporated motions from real world actions (e.g...Comparison of Executive Attention Function in Normally-aging Long - term Tai Chi, Meditation, and Aerobic Fitness Practitioners vs. Sedentary Adults...on short - term plasticity,” Experimental Brain Research, vol. 213, pp. 415-422, 2011. 16. J.L. Etnier and Y-K. Chang, “The effect of physical

  19. A Prospective Comparative Study of the Toxicity Profile of 5-Flurouracil, Adriamycin, Cyclophosphamide Regime VS Adriamycin, Paclitaxel Regime in Patients with Locally Advanced Breast Carcinoma

    Science.gov (United States)

    Pillai, Pradeep Sadasivan; Jayakumar, Krishnan Nair Lalithamma

    2015-01-01

    Introduction A 5-flurouracil, Adriamycin, Cyclophosphamide (FAC) and Adriamycin, Paclitaxel (AT) are two popular chemotherapeutic regimens for treatment of breast carcinoma. The most time tested and popular regimen is FAC. It is extensively studied for efficacy and toxicity. But data regarding toxicity profile and efficacy of AT regimen is sparse. Aim To study the toxicity profile, severity of toxicities and clinical response rate of FAC and AT regimens in patients with locally advanced breast carcinoma. Materials and Methods A prospective observational study with 50 patients in each treatment arm. Study duration was 12 months from November 2012 to October 2013. Consecutive patients with locally advanced breast carcinoma receiving treatment with either FAC or AT regimen, satisfying inclusion criteria were enrolled into the study after getting informed written consent. Prior to initiation of treatment detailed medical history was taken from all patients. General clinical examination, examination of organ systems and local examination of breast lump were done. After each cycle of chemotherapy and after completion of treatment patients were interviewed and examined for clinical response and toxicities. Toxicities were graded with WHO toxicity grading criteria. All data were entered in a structured proforma. At least 50% reduction in tumour size was taken as adequate clinical response. Statistical Analysis Data was analysed using Chi-square test with help of Excel 2007 and SPSS-16 statistical software. Results Different pattern of toxicities were seen with FAC and AT regimens. Anaemia, thrombocytopenia, stomatitis, hyperpigmentation, photosensitivity and diarrhoea were more common with patients receiving FAC regimen. Leucopenia, peripheral neuropathy, myalgia, arthralgia, vomiting and injection site reactions were more common in AT regimen. Both FAC and AT regimens gave 100% clinical response. Conclusion FAC and AT regimens are equally efficacious but have different

  20. Positive Association of Fibroadenomatoid Change with HER2-Negative Invasive Breast Cancer: A Co-Occurrence Study.

    Directory of Open Access Journals (Sweden)

    Yaqin Chen

    Full Text Available Risk assessment of a benign breast disease/lesion (BBD for invasive breast cancer (IBC is typically done through a longitudinal study. For an infrequently-reported BBD, the shortage of occurrence data alone is a limiting factor to conducting such a study. Here we present an approach based on co-occurrence analysis, to help address this issue. We focus on fibroadenomatoid change (FAC, an under-studied BBD, as our preliminary analysis has suggested its previously unknown significant co-occurrence with IBC.A cohort of 1667 female patients enrolled in the Clinical Breast Care Project was identified. A single experienced breast pathologist reviewed all pathology slides for each case and recorded all observed lesions, including FAC. Fibroadenoma (FA was studied for comparison since FAC had been speculated to be an immature FA. FA and Fibrocystic Changes (FCC were used for method validation since they have been comprehensively studied. Six common IBC and BBD risk/protective factors were also studied. Co-occurrence analyses were performed using logistic regression models.Common risk/protective factors were associated with FA, FCC, and IBC in ways consistent with the literature in general, and they were associated with FAC, FA, and FCC in distinct patterns. Age was associated with FAC in a bell-shape curve so that middle-aged women were more likely to have FAC. We report for the first time that FAC is positively associated with IBC with odds ratio (OR depending on BMI (OR = 6.78, 95%CI = 3.43-13.42 at BMI25 kg/m2. This association is only significant with HER2-negative IBC subtypes.We conclude that FAC is a candidate risk factor for HER2-negative IBCs, and it is a distinct disease from FA. Co-occurrence analysis can be used for initial assessment of the risk for IBC from a BBD, which is vital to the study of infrequently-reported BBDs.

  1. Positive Association of Fibroadenomatoid Change with HER2-Negative Invasive Breast Cancer: A Co-Occurrence Study

    Science.gov (United States)

    Kovatich, Albert J.; Hooke, Jeffrey A.; Liu, Jianfang; Kvecher, Leonid; Fantacone-Campbell, J. Leigh; Mitchell, Edith P.; Rui, Hallgeir; Shriver, Craig D.; Hu, Hai

    2015-01-01

    Background Risk assessment of a benign breast disease/lesion (BBD) for invasive breast cancer (IBC) is typically done through a longitudinal study. For an infrequently-reported BBD, the shortage of occurrence data alone is a limiting factor to conducting such a study. Here we present an approach based on co-occurrence analysis, to help address this issue. We focus on fibroadenomatoid change (FAC), an under-studied BBD, as our preliminary analysis has suggested its previously unknown significant co-occurrence with IBC. Methods A cohort of 1667 female patients enrolled in the Clinical Breast Care Project was identified. A single experienced breast pathologist reviewed all pathology slides for each case and recorded all observed lesions, including FAC. Fibroadenoma (FA) was studied for comparison since FAC had been speculated to be an immature FA. FA and Fibrocystic Changes (FCC) were used for method validation since they have been comprehensively studied. Six common IBC and BBD risk/protective factors were also studied. Co-occurrence analyses were performed using logistic regression models. Results Common risk/protective factors were associated with FA, FCC, and IBC in ways consistent with the literature in general, and they were associated with FAC, FA, and FCC in distinct patterns. Age was associated with FAC in a bell-shape curve so that middle-aged women were more likely to have FAC. We report for the first time that FAC is positively associated with IBC with odds ratio (OR) depending on BMI (OR = 6.78, 95%CI = 3.43-13.42 at BMI25 kg/m2). This association is only significant with HER2-negative IBC subtypes. Conclusions We conclude that FAC is a candidate risk factor for HER2-negative IBCs, and it is a distinct disease from FA. Co-occurrence analysis can be used for initial assessment of the risk for IBC from a BBD, which is vital to the study of infrequently-reported BBDs. PMID:26098961

  2. Dynamic grid refinement for partial differential equations on parallel computers

    International Nuclear Information System (INIS)

    Mccormick, S.; Quinlan, D.

    1989-01-01

    The fast adaptive composite grid method (FAC) is an algorithm that uses various levels of uniform grids to provide adaptive resolution and fast solution of PDEs. An asynchronous version of FAC, called AFAC, that completely eliminates the bottleneck to parallelism is presented. This paper describes the advantage that this algorithm has in adaptive refinement for moving singularities on multiprocessor computers. This work is applicable to the parallel solution of two- and three-dimensional shock tracking problems. 6 refs

  3. Pre-operative Tei Index does not predict left ventricular function immediately after mitral valve repair

    Directory of Open Access Journals (Sweden)

    Chirojit Mukherjee

    2012-01-01

    Full Text Available Echocardiographic assessment of systolic left ventricular (LV function in patients with severe mitral regurgitation (MR undergoing mitral valve (MV repair can be challenging because the measurement of ejection fraction (EF or fractional area change (FAC in pathological states is of questionable value. The aim of our study was to evaluate the usefulness of the pre-operative Tei Index in predicting left ventricular EF or FAC immediately after MV repair. One hundred and thirty patients undergoing MV repair with sinus rhythm pre- and post-operatively were enrolled in this prospective study. Twenty-six patients were excluded due to absence of sinus rhythm post-operatively. Standard transesophageal examination(IE 33,Philips,Netherlands was performed before and after cardiopulmonary bypass according to the guidelines of the ASE/SCA. FAC was determined in the transgastric midpapillary short-axis view. LV EF was measured in the midesophageal four- and two-chamber view. For calculation of the Tei Index, the deep transgastric and the midesophageal four-chamber view were used. Statistical analysis was performed with SPSS 17.0. values are expressed as mean with standard deviation. LV FAC and EF decreased significantly after MV repair (FAC: 56±12% vs. 50±14%, P<0.001; EF: 58±11 vs. 50±12Έ P<0.001. The Tei Index decreased from 0.66±0.23 before MV repair to 0.41±0.19 afterwards (P<0.001. No relationship between pre-operative Tei Index and post-operative FAC or post-operative EF were found (FAC: r=−0.061, P=0.554; EF: r=−0.29, P=0.771. Conclusion: Pre-operative Tei Index is not a good predictor for post-operative FAC and EF in patients undergoing MV repair.

  4. Quantitative Evaluation of the Fetal Right and Left Ventricular Fractional Area Change Using Speckle Tracking Technology.

    Science.gov (United States)

    DeVore, Greggory R; Klas, Berthold; Satou, Gary; Sklansky, Mark

    2018-03-14

    The purpose of this study was to measure the fractional area change (FAC) of the right and left ventricles in normal fetal hearts between 20 and 40 weeks of gestation using speckle-tracking software. The 4-chamber view of the fetal heart was obtained in 200 control fetuses between 20 and 40 weeks of gestation. The FAC was computed from the ventricular areas [((end-diastolic area) - (end-systolic area)/(end-diastolic area)) x 100] for the right and left ventricles and regressed against 7 independent biometric and age variables. The FAC was correlated with longitudinal fractional shortening (LFS) [((end-diastolic longitudinal length) - (end-systolic longitudinal length) /(end-diastolic longitudinal length)) x 100] obtained from the mid ventricular basal-apical lengths of the right and left ventricular chambers and the transverse fractional shortening (TFS) [((end-diastolic transverse length) - (end-systolic transverse length)/(end-diastolic transverse length)) x 100] from three transverse positions (base, mid, apical) located within each ventricular chamber. To evaluate potential clinical utility, the FAC, LFS, and TFS results were examined in 9 fetuses with congenital heart defects (CHD). Regression analysis demonstrated significant associations between the FAC and the biometric and age independent variables (R 2 = 0.13 - 0.15). The FAC was significantly correlated with the LFS (R 2 =0.18 to 0.28) and TFS (R 2 = 0.13 to 0.33). The 9 fetuses with CHD illustrated the interrelationship between the FAC, LFS, and TFS when identifying abnormal ventricular function. This study reports results from measuring the FAC of the right and left ventricles, and demonstrates a correlation with longitudinal fractional shortening (LFS) and transverse fractional shortening (TFS). This article is protected by copyright. All rights reserved.

  5. Wall thinning trend analyses for secondary side piping of Korean NPPs

    International Nuclear Information System (INIS)

    Hwang, K.M.; Jin, T.E.; Lee, S.H.; Jeon, S.C.

    2003-01-01

    Since the mid-1990s, nuclear power plants in Korea have experienced wall thinning, leaks, and ruptures of secondary side piping caused by flow-accelerated corrosion (FAC). The pipe failures have increased as operating time progresses. In order to prevent the FAC-induced pipe failures and to develop an effective FAC management strategy, KEPRI and KOPEC have conducted a study for developing systematic FAC management technology for secondary side piping of all Korean nuclear power plants. As a part of the study, FAC analyses were performed using the CHECWORKS code. The analysis results were used to select components for inspection and to determine inspection intervals on each nuclear power plant. This paper describes the introduction of the FAC analysis method and the wall thinning trend analysis results by reactor type, system, and water treatment amine. This paper also represents the site application feasibility for secondary side piping management. The site application feasibility of the analysis results was proven by comparisons of predicted and measured wear rates. (author)

  6. Correlations between Geomagnetic Disturbances and Field-Aligned Currents during the 22-29 July 2004 Storm Time Interval

    Science.gov (United States)

    Hood, R.; Woodroffe, J. R.; Morley, S.; Aruliah, A. L.

    2017-12-01

    Using the CHAMP fluxgate magnetometer to calculate field-aligned current (FAC) densities and magnetic latitudes, with SuperMAG ground magnetometers analogously providing ground geomagnetic disturbances (GMD) magnetic perturbations and latitudes, we probe FAC locations and strengths as predictors of GMD locations and strengths. We also study the relationships between solar wind drivers and global magnetospheric activity, and both FACs and GMDs using IMF Bz and the Sym-H index. We present an event study of the 22-29 July 2004 storm time interval, which had particularly large GMDs given its storm intensity. We find no correlation between FAC and GMD magnitudes, perhaps due to CHAMP orbit limitations or ground magnetometer coverage. There is, however, a correlation between IMF Bz and nightside GMD magnitudes, supportive of their generation via tail reconnection. IMF Bz is also correlated with dayside FAC and GMD magnetic latitudes, indicating solar wind as an initial driver. The ring current influence increases during the final storm, with improved correlations between the Sym-H index and both FAC magnetic latitudes and GMD magnitudes. Sym-H index correlations may only be valid for higher intensity storms; a statistical analysis of many storms is needed to verify this.

  7. Correlation of flow accelerated corrosion rate with iron solubility

    International Nuclear Information System (INIS)

    Fujiwara, K.; Domae, M.; Yoneda, K.; Inada, F.; Ohira, T.; Hisamune, K.

    2011-01-01

    Flow accelerated corrosion (FAC) of the carbon steel is one of the most important subjects in the coolant systems of the power plants. FAC is influenced by the composition of the material, the flow condition, temperature, and the water chemistry conditions. It is considered that the solubility of iron (Fe) is the most important factor in the water chemistry parameters affecting FAC. In the present study, the effects of temperature and pH on the Fe solubility were evaluated in consideration of the hydrolysis reactions of the ferrous iron, the dissolution equilibria of Fe 3 O 4 , FeO, and Fe(OH) 2 , and the charge balance. The correlation between the Fe solubility and the FAC behavior was discussed. It has been suggested that the product of the Fe solubility equilibrated with Fe 3 O 4 and the mass transfer coefficient can explain the temperature and pH dependence of FAC. These results indicate the presence of the magnetite on the surface of the carbon steel. Diffusion of the Fe from the saturated layer to the bulk solution determines the FAC rate from the water chemistry aspect.

  8. Evaluation of flow accelerated corrosion by coupled analysis of corrosion and flow dynamics. Relationship of oxide film thickness, hematite/magnetite ratio, ECP and wall thinning rate

    International Nuclear Information System (INIS)

    Uchida, Shunsuke; Naitoh, Masanori; Okada, Hidetoshi; Uehara, Yasushi; Koshizuka, Seiichi

    2011-01-01

    Systematic approaches to evaluate flow accelerated corrosion (FAC) are desired before discussing application of countermeasures for FAC. First, future FAC occurrence should be evaluated to identify locations where a higher possibility of FAC occurrence exists, and then, wall thinning rate at the identified FAC occurrence zone is evaluated to obtain the preparation time for applying countermeasures. Wall thinning rates were calculated with two coupled models: 1.static electrochemical analysis and 2.dynamic oxide layer growth analysis. The anodic current density and the electrochemical corrosion potential (ECP) were calculated with the static electrochemistry model based on an Evans diagram. The ferrous ion release rate, determined by the anodic current density, was applied as input for the dynamic double oxide layer model. Some of the dissolved ferrous ion was removed to the bulk water and others precipitated on the surface as magnetite particles. The thickness of oxide layer was calculated with the dynamic oxide layer growth model and then its value was used as input in the electrochemistry model. It was confirmed that the calculated results (corrosion rate and ECP) based on the coupled models were in good agreement with the measured ones. Higher ECP was essential for preventing FAC rate. Moderated conditions due to lower mass transfer coefficients resulted in thicker oxide layer thickness and then higher ECP, while moderated corrosion conditions due to higher oxidant concentrations resulted in larger hematite/magnetite rate and then higher ECP.

  9. Evaluation of flow accelerated corrosion by coupled analysis of corrosion and flow dynamics (3), relationship of oxide film thickness, hematite/magnetite ratio, ECP and wall thinning rate

    International Nuclear Information System (INIS)

    Uchida, Shunsuke; Naitoh, Masanori; Okada, Hidetoshi; Uehara, Yasushi; Koshizuka, Seiichi

    2009-01-01

    Systematic approaches for evaluating flow accelerated corrosion (FAC) are desired before discussing application of countermeasures for FAC. Firstly, future FAC occurrence should be evaluated to identify locations where a higher possibility of FAC occurrence exists, and then, wall thinning rate at the identified FAC occurrence zone is evaluated to obtain the preparation time for applying countermeasures. Wall thinning rates were calculated with the coupled models of static electrochemical analysis and dynamic double oxide layer analysis. Anodic current density and electrochemical corrosion potential (ECP) were calculated with the static electrochemistry model based on an Evans diagram and ferrous ion release rate determined by the anodic current density was applied as input for the dynamic double oxide layer model. Some of the dissolved ferrous ion was removed to the bulk water and others precipitated on the surface as magnetite particles. The thickness of oxide layer was calculated with the dynamic double oxide layer model and then was applied as input for the electrochemistry model. It was confirmed that the calculated results based on the coupled models resulted good agreement with the measured ones. Higher ECP was essential for preventing FAC rate. Moderated conditions due to lower mass transfer coefficients resulted in thicker oxide layer thickness and then higher ECP, while moderated corrosion conditions due to higher oxidant concentrations resulted in larger hematite/magnetite rate and then higher ECP. (author)

  10. Effects of water chemistry on flow accelerated corrosion and liquid droplet impingement

    International Nuclear Information System (INIS)

    Uchida, Shunsuke; Naitoh, Masanori; Okada, Hidetoshi; Uehara, Yasushi; Koshizuka, Seiichi; Lister, Derek H.

    2009-01-01

    Overlapping effects of flow dynamics and corrosion are important issues to determine reliability and lifetime of major structures and components in light water reactor plants. Flow accelerated corrosion (FAC) and liquid droplet impingement (LDI) are typical phenomena due to both interactions. In order to evaluation local wall thinning due to FAC and LDI, 6 step evaluation procedures have been proposed. (1) Flow pattern along the flow path was obtained with 1D computational flow dynamics (CFD) codes, (2) Corrosive conditions, e.g., oxygen concentration along the flow path were calculated with a hydrazine oxygen reaction code for FAC evaluation, while flow pattern of liquid droplets in high velocity steam and possibility of their collision to pipe inner surface were evaluated for LDI evaluation. (3) Mass transfer coefficient at the structure surface was calculated with 3D CFD codes for FAC evaluation, while frequency of oxide film rupture due to droplet collision was calculated for LDI evaluation. (4) High risk zones for FAC/LDI occurrence were evaluated by coupling major parameters, and then, (5) Wall thinning rates were calculated with the coupled model of static electrochemical analysis and dynamic double oxide layer analysis at the identified high FAC/LDI risk zone. (author)

  11. Theoretical modeling of mechanical homeostasis of a mammalian cell under gravity-directed vector.

    Science.gov (United States)

    Zhou, Lüwen; Zhang, Chen; Zhang, Fan; Lü, Shouqin; Sun, Shujin; Lü, Dongyuan; Long, Mian

    2018-02-01

    Translocation of dense nucleus along gravity vector initiates mechanical remodeling of a eukaryotic cell. In our previous experiments, we quantified the impact of gravity vector on cell remodeling by placing an MC3T3-E1 cell onto upward (U)-, downward (D)-, or edge-on (E)- orientated substrate. Our experimental data demonstrate that orientation dependence of nucleus longitudinal translocation is positively correlated with cytoskeletal (CSK) remodeling of their expressions and structures and also is associated with rearrangement of focal adhesion complex (FAC). However, the underlying mechanism how CSK network and FACs are reorganized in a mammalian cell remains unclear. In this paper, we developed a theoretical biomechanical model to integrate the mechanosensing of nucleus translocation with CSK remodeling and FAC reorganization induced by a gravity vector. The cell was simplified as a nucleated tensegrity structure in the model. The cell and CSK filaments were considered to be symmetrical. All elements of CSK filaments and cytomembrane that support the nucleus were simplified as springs. FACs were simplified as an adhesion cluster of parallel bonds with shared force. Our model proposed that gravity vector-directed translocation of the cell nucleus is mechanically balanced by CSK remodeling and FAC reorganization induced by a gravitational force. Under gravity, dense nucleus tends to translocate and exert additional compressive or stretching force on the cytoskeleton. Finally, changes of the tension force acting on talin by microfilament alter the size of FACs. Results from our model are in qualitative agreement with those from experiments.

  12. Application of Nano-Structured Coatings for Mitigation of Flow-Accelerated Corrosion in Secondary Pipe Systems of Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Seung Hyun; Kim, Jong Jin; Yoo, Seung Chang; Huh, Jae Hoon; Kim, Ji Hyun [Ulsan National Institute of Science and Technology, Ulsan (Korea, Republic of)

    2014-05-15

    Flow-accelerated corrosion (FAC) is a complex corrosion process combined with mechanical reaction with fluid. There were lots of research to mitigate FAC such as controlling temperature or water chemistry but in this research, we adopt active coating techniques especially nano-particle reinforced coatings. One of the general characteristics of FAC and its mitigation is that surface friction due to surface morphology makes a significant effect on FAC. Therefore to form a uniform coating layers, nano-particles including TiO2, SiC, Fe-Cr-W and Graphene were utilized. Those materials are known as greatly improve the corrosion resistance of substrates such as carbon steels but their effects on mitigation of FAC are not revealed clearly. Therefore in this research, the FAC resistive performance of nano-structured coatings were tested by electrochemical impedance spectroscopy (EIS) in room temperature 15 wt% sulfuric acid. As the flow-accelerated corrosion inhibitors in secondary piping system of nuclear power plants, various kinds of nano-structured coatings were prepared and tested in room-temperature electrochemical cells. SHS7740 with two types of Densifiers, electroless nickel plating with TiO2 are prepared. Electropolarization curves shows the outstanding corrosion mitigation performance of SHS7740 but EIS results shows the promising potential of Ni-P and Ni-P-TiO2 electroless nickel plating. For future work, high-temperature electrochemical analysis system will be constructed and in secondary water chemistry will be simulated.

  13. Feasibility Study on Nano-structured Coatings to Mitigate Flow-accelerated Corrosion in Secondary System of Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Seunghyun; Kim, Jeong Won; Kim, Ji Hyun [Ulsan National Institute of Science and Technology, Banyeon-ri, Eonyang-eup, Ulju-gun, Ulsan (Korea, Republic of)

    2015-05-15

    There have been many efforts to mitigate FAC through the adoption of the advanced and modified water chemistries such as optimized dissolved oxygen (DO) concentration and temperature. However, these mitigation techniques pose certain challenges relating to the compatibility of new water chemistries with the steam generator, the thermal efficiency of the secondary side, etc. In this context, nano-particle reinforced electroless nickel plating (NP ENP) could help solve the FAC issues in secondary pipe systems. This does not require modification of water chemistry or structural materials, and hence, its application is reasonable and time-saving compared to previous FAC mitigation techniques. The main parameters of FAC are known as electrochemical reaction at the interface, dissolution of magnetite and ferrous ions due to concentration gradient between carbon steels and water and wear due to a fast-flowing fluid. High-temperature corrosion characteristics of the both coatings have potential as FAC barrier for carbon steel. Feasibility study will be carried out with FAC simulation experiments.

  14. Management of hypotony and flat anterior chamber associated with glaucoma filtration surgery

    Directory of Open Access Journals (Sweden)

    Yavuz Tunç

    2015-10-01

    Full Text Available AIM:To determine the effectiveness of pharmacological and interventional treatment of hypotony and flat anterior chamber (FAC resulting from glaucoma filtration surgery.METHODS:We retrospectively examined the medical records of fifty-two trabeculectomy patients (52 eyes who developed postoperative hypotony and FAC. The management and associated complications of hypotony, changing intraocular pressure (IOP and best corrected visual acuity (BCVA were evaluated.RESULT:Of the 52 patients with hypotony, 29 (56% had a grade 1 FAC, 21 (40% had a grade 2 FAC, and only 2 had a grade 3 FAC. There was no significant difference between the mean preoperative IOP and the mean IOP at three and six months after surgery. Thirteen eyes (25% required antiglaucomatous medication three months after surgery. The mean BCVA at 6mo after surgery was significantly reduced as compared with the mean preoperative BCVA.CONCLUSION:Hypotonia and FAC following trabeculectomy are associated with troublesome complications that require pharmacological and/or surgical treatment. Thus, close follow-up is essential for affected patients.

  15. Assessment of Pipe Wall Loss Using Guided Wave Testing

    International Nuclear Information System (INIS)

    Joo, Kyung Mun; Jin, Seuk Hong; Moon, Yong Sig

    2010-01-01

    Flow accelerated corrosion(FAC) of carbon steel pipes in nuclear power plants has been known as one of the major degradation mechanisms. It could have bad influence on the plant reliability and safety. Also detection of FAC is a significant cost to the nuclear power plant because of the need to remove and replace insulation. Recently, the interest of the guided wave testing(GWT) has grown because it allows long range inspection without removing insulation of the pipe except at the probe position. If GWT can be applied to detection of FAC damages, it will can significantly reduce the cost for the inspection of the pipes. The objective of this study was to determine the capability of GWT to identify location of FAC damages. In this paper, three kinds of techniques were used to measure the amplitude ratio between the first and the second welds at the elbow area of mock-ups that contain real FAC damages. As a result, optimal inspection technique and minimum detectability to detect FAC damages drew a conclusion

  16. Effect of water chemistry improvement on flow accelerated corrosion in light-water nuclear reactor

    International Nuclear Information System (INIS)

    Sugino, Wataru; Ohira, Taku; Nagata, Nobuaki; Abe, Ayumi; Takiguchi, Hideki

    2009-01-01

    Flow Accelerated Corrosion (FAC) of Carbon Steel (CS) piping has been one of main issues in Light-Water Nuclear Reactor (LWRs). Wall thinning of CS piping due to FAC increases potential risk of pipe rupture and cost for inspection and replacement of damaged pipes. In particular, corrosion products generated by FAC of CS piping brought steam generator (SG) tube corrosion and degradation of thermal performance, when it intruded and accumulated in secondary side of PWR. To preserve SG integrity by suppressing the corrosion of CS, High-AVT chemistry (Feedwater pH9.8±0.2) has been adopted to Tsuruga-2 (1160 MWe PWR, commercial operation in 1987) in July 2005 instead of conventional Low-AVT chemistry (Feedwater pH 9.3). By the High-AVT adoption, the accumulation rate of iron in SG was reduced to one-quarter of that under conventional Low-AVT. As a result, a tendency to degradation of the SG thermal efficiency was improved. On the other hand, it was clarified that High-AVT is ineffective against Flow Accelerated Corrosion (FAC) at the region where the flow turbulence is much larger. By contrast, wall thinning of CS feed water pipes due to FAC has been successfully controlled by oxygen treatment (OT) for long time in BWRs. Because Magnetite film formed on CS surface under AVT chemistry has higher solubility and porosity in comparison with Hematite film, which is formed under OT. In this paper, behavior of the FAC under various pH and dissolved oxygen concentration are discussed based on the actual wall thinning rate of BWR and PWR plant and experimental results by FAC test-loop. And, it is clarified that the FAC is suppressed even under extremely low DO concentration such as 2ppb under AVT condition in PWR. Based on this result, we propose the oxygenated water chemistry (OWC) for PWR secondary system which can mitigate the FAC of CS piping without any adverse effect for the SG integrity. Furthermore, the applicability and effectiveness of this concept developed for FAC

  17. Cause Analysis of Flow Accelerated Corrosion and Erosion-Corrosion Cases in Korea Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Y. S.; Lee, S. H. [Korea Hydro and Nuclear Power Co., Ltd., Gyeongju (Korea, Republic of); Hwang, K. M. [KEPCO Engineering and Construction Company, Gimcheon (Korea, Republic of)

    2016-08-15

    Significant piping wall thinning caused by Flow-Accelerated Corrosion (FAC) and Erosion-Corrosion (EC) continues to occur, even after the Mihama Power Station unit 3 secondary pipe rupture in 2004, in which workers were seriously injured or died. Nuclear power plants in many countries have experienced FAC and EC-related cases in steam cycle piping systems. Korea has also experienced piping wall thinning cases including thinning in the downstream straight pipe of a check valve in a feedwater pump line, the downstream elbow of a control valve in a feedwater flow control line, and failure of the straight pipe downstream of an orifice in an auxiliary steam return line. Cause analyses were performed by reviewing thickness data using Ultrasonic Techniques (UT) and, Scanning Electron Microscope (SEM) images for the failed pipe, and numerical simulation results for FAC and EC cases in Korea Nuclear Power Plants. It was concluded that the main cause of wall thinning for the downstream pipe of a check valve is FAC caused by water vortex flow due to the internal flow shape of a check valve, the main cause of wall thinning for the downstream elbow of a control valve is FAC caused by a thickness difference with the upstream pipe, and the main cause of wall thinning for the downstream pipe of an orifice is FAC and EC caused by liquid droplets and vortex flow. In order to investigate more cases, additional analyses were performed with the review of a lot of thickness data for inspected pipes. The results showed that pipe wall thinning was also affected by the operating condition of upstream equipment. Management of FAC and EC based on these cases will focus on the downstream piping of abnormal or unusual operated equipment.

  18. Perioperative echocardiography-derived right ventricle function parameters and early outcomes after tetralogy of Fallot repair in mid-childhood: a single-center, prospective observational study.

    Science.gov (United States)

    Raj, Ravi; Puri, Goverdhan Dutt; Jayant, Aveek; Thingnam, Shyam Kumar Singh; Singh, Rana Sandip; Rohit, Manoj Kumar

    2016-11-01

    Right ventricular (RV) function alterations are invariably present in all patients after tetralogy of Fallot (TOF) repair. Unlike the developed world where most of the patients with TOF are corrected in infancy, average age of presentation and thus surgery for these patients in the developing world may be higher. We aimed to study the correlation between RV function parameters such as tricuspid annular peak systolic excursion (TAPSE), fractional area change (FAC), and tricuspid annular peak systolic velocity (S') with early outcome variables after intracardiac repair for TOF. Fifty patients with a preoperative diagnosis of tetralogy of Fallot scheduled for corrective surgery were included in this single-center, prospective observational study. A preoperative transthoracic echocardiogram was performed to measure RV function parameters (FAC0, TAPSE0, S'0). Transthoracic echocardiography was repeated postoperatively to measure FAC1, TAPSE1, S'1 (day 1) and FAC2, TAPSE2, and S'2 (day 3). The relationship between preoperative and postoperative RV function parameters with in-hospital mortality, duration of mechanical ventilation, and intensive care unit stay was studied. The median age of patients was 6 years (range 1-14 years). Multiple stepwise logistic regression analysis showed RV FAC as best predictor of clinical outcome. Area under the receiver operating characteristic curve for postoperative RV function parameters, that is, FAC, TAPSE, and S' to predict early or delayed recovery was 0.944, 0.875, and 0.655, respectively. Among the RV function parameters studied, RV FAC best predicted the early outcome variables after TOF repair, followed by TAPSE while lateral tricuspid annular velocity S' being the least predictive. © 2016, Wiley Periodicals, Inc.

  19. Fluid-structure-interaction analysis for welded pipes with flow-accelerated corrosion wall thinning

    Energy Technology Data Exchange (ETDEWEB)

    Sun, L.; Ding, Y., E-mail: lan.sun@cnl.ca [Canadian Nuclear Laboratories, Chalk River, Ontario (Canada)

    2016-06-15

    The flow-accelerated corrosion (FAC) entrance effect results in enhanced wall thinning immediately downstream of a weld if the weld connects an upstream FAC-resistant material with a downstream less resistant material. The weld regions, especially those with local repairs, are susceptible to cracking due to the high residual stresses induced by fabrication. The combined effects of the FAC entrance effect and high stresses at a weld might compromise the structural integrity of the piping and lead to a failure. Weld degradation by FAC entrance effect has been observed at nuclear and fossil power plants. This paper describes an application using fluid-structure-interaction (FSI) modelling to study the combined effects of FAC wall thinning, weld residual stresses, and in-service loads on welded structures. Simplified cases analyzed were based on CANDU outlet feeder conditions. The analysis includes the flow and mass transfer modelling of the FAC entrance effect using computational fluid dynamics (CFD) and nonlinear structural analyses of the welded structures with wall thinning and an assumed weld residual stress and strain distribution. The FSI analyses were performed using ANSYS Workbench, an integrated platform that enables the coupling of CFD and structural analysis solutions. The obtained results show that the combination of FAC, weld residual stresses, in-service loads (including the internal pressure) and (or) extreme loads could cause high stresses and affect the integrity of the welded pipes. The present work demonstrated that the FSI modelling can be used as an effective approach to assess the integrity of welded structures. (author)

  20. Cation-Dependent Light-Induced Halide Demixing in Hybrid Organic-Inorganic Perovskites.

    Science.gov (United States)

    Sutter-Fella, Carolin M; Ngo, Quynh P; Cefarin, Nicola; Gardner, Kira L; Tamura, Nobumichi; Stan, Camelia V; Drisdell, Walter S; Javey, Ali; Toma, Francesca M; Sharp, Ian D

    2018-06-13

    Mixed cation metal halide perovskites with increased power conversion efficiency, negligible hysteresis, and improved long-term stability under illumination, moisture, and thermal stressing have emerged as promising compounds for photovoltaic and optoelectronic applications. Here, we shed light on photoinduced halide demixing using in situ photoluminescence spectroscopy and in situ synchrotron X-ray diffraction (XRD) to directly compare the evolution of composition and phase changes in CH(NH 2 ) 2 CsPb-halide (FACsPb-) and CH 3 NH 3 Pb-halide (MAPb-) perovskites upon illumination, thereby providing insights into why FACs-perovskites are less prone to halide demixing than MA-perovskites. We find that halide demixing occurs in both materials. However, the I-rich domains formed during demixing accumulate strain in FACsPb-perovskites but readily relax in MA-perovskites. The accumulated strain energy is expected to act as a stabilizing force against halide demixing and may explain the higher Br composition threshold for demixing to occur in FACsPb-halides. In addition, we find that while halide demixing leads to a quenching of the high-energy photoluminescence emission from MA-perovskites, the emission is enhanced from FACs-perovskites. This behavior points to a reduction of nonradiative recombination centers in FACs-perovskites arising from the demixing process and buildup of strain. FACsPb-halide perovskites exhibit excellent intrinsic material properties with photoluminescence quantum yields that are comparable to MA-perovskites. Because improved stability is achieved without sacrificing electronic properties, these compositions are better candidates for photovoltaic applications, especially as wide bandgap absorbers in tandem cells.