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Sample records for hjorth holger pedersen

  1. Holger Loodus / Holger Loodus

    Index Scriptorium Estoniae

    Loodus, Holger

    2000-01-01

    Ansambli "Dallas" kitarrist Holger Loodus kirjutab oma olulisematest plaatidest:Blondie "The Best Of Blondie", Peter Sarstedt "Peter Sarstedt", Collage "Kadriko", Kraftwerk "Man Machine", Nansy Sinatra ja Lee Hazlewood "The Hits Of Nancy & Lee", The Modern Jazz Quarte "Third Stream Music"

  2. Holger Loodus ja maalikunst = Holger Loodus and painting / Indrek Grigor

    Index Scriptorium Estoniae

    Grigor, Indrek, 1981-

    2016-01-01

    Holger Looduse isiknäitus "Urlaub" Vaal galeriis Tallinnas. Galeriis on viis õlimaali, kolm töödeldud fotot, üks tehniline installatsioon ja üks videoinstallatsioon. Keskne teema - puhkus ja reisimine

  3. Paul B. Pedersen (1936-2017).

    Science.gov (United States)

    Lonner, Walter J; Draguns, Juris G

    2018-01-01

    Presents an obituary for Paul B. Pedersen, who passed away on January 11, 2017, in a Minnetonka, Minnesota hospital. In 1973 Pedersen convened a pathfinding APA (Division 9) symposium in Montreal that resulted in the publication in 1976 of Counseling Across Cultures (Pedersen, Lonner, and Draguns, Eds.). The first book of its kind, it became the "Granddaddy" of all subsequent books in that area. The seventh edition, published in 2016 (with Trimble and Scharron-del Rio, co-eds), benefitted from his steadfast encouragement, but his deteriorating health prevented a more active role. His epitaph may well be one of his wisest and oft-quoted sayings: "All interviewing and counseling is multicultural. Each client comes to the session embodying multiple voices from the past." (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  4. Find Holger - også en anden gang

    DEFF Research Database (Denmark)

    Albrechtslund, Anders

    2011-01-01

    Vi fandt Holger! Solstrålehistorien om den 3-årige dreng, der gik sin vej og siden blev fundet igen, er gået verden rundt. Den gode nyhed giver anledning til at tænke over, hvorfor vi egentlig fandt Holger uskadt?...

  5. Charles J. Pedersen's legacy to chemistry.

    Science.gov (United States)

    Izatt, Reed M

    2017-05-09

    The serendipitous discovery in 1961 of dibenzo-18-crown-6 by Charles J. Pedersen marked the beginning of research on cyclic polyether macrocyclic compounds. These compounds have a remarkably selective affinity for certain metal ions and provide a framework for studying molecular recognition processes. Pedersen's work excited much interest in the scientific community and fueled important advances in macrocyclic and supramolecular chemistry. Born in Korea of a Japanese mother and a Norwegian engineer father, he was educated in Japan and later graduated from the University of Dayton (BS, chemical engineering) and Massachusetts Institute of Technology (MS, chemistry). He worked at du Pont for 42 years as a research chemist. His research talent at du Pont earned him an appointment as a Research Associate allowing him to pursue research as he chose. This freedom served him well making it possible for him to devote all his efforts following his discovery of dibenzo-18-crown-6 until his retirement to synthesis of cyclic polyethers and evaluation of their metal ion complexation properties. His influence on macrocyclic and supramolecular chemistry has been pervasive. He was co-recipient of the 1987 Nobel Prize in chemistry for development and use of molecules with structure-specific interactions of high selectivity. The year 2017 marks the fiftieth anniversary of the publication of his first paper describing his synthesis of over 50 crown ethers.

  6. Taju vormiv arhitektuur / Eva Castro, Holger Kehne ; interv. Inga Raukas

    Index Scriptorium Estoniae

    Castro, Eva

    2002-01-01

    Londoni arhitektuuribüroo Plasma Studio arhitektid Eva Castro (s. 1969 Argentiinas) ja Holger Kehne (s. 1970 Saksamaal) räägivad oma tööst ja arhitektuurist. Loetletud büroo tähtsamad arhitektuuriauhinnad ja projektid. Osalesid 5. Põhja- ja Baltimaade arhitektuuritriennaalil

  7. Edgar Savisaar : Mina ei anna mitte mingit hinnangut / Edgar Savisaar ; interv. Dannar Leitmaa, Holger Roonemaa

    Index Scriptorium Estoniae

    Savisaar, Edgar, 1950-

    2008-01-01

    Tallinna linnapea vastused linnavalitsuse pressikonverentsil küsimustele, mis puudutasid Keskerakonna suurrahastaja Oliver Kruuda omavolilist ehitamist Nõmmel. Vt. samas: Holger Roonemaa. Inspektorid ei pannud Kruuda tegevust tähele

  8. Dos obras de Kohn-Pedersen-Fox/EE.UU

    Directory of Open Access Journals (Sweden)

    Editorial, Equipo

    1985-12-01

    Full Text Available Two works by Pedersen Fox Associates PC are described in this article. In the first one, the play of volumes and the curved curtain wall façade are the leading part defining the building. At the same time it must be pointed out the decorative use of the different cladding materials and the contrast between the base of the volume and its upper part, of a very different feature from the point of view of the design. The second work takes benefit of the site with symbolic aims as for its façade, the whole being harmonized around a gardened inner court full colored.En la primera de ellas juegan un papel decisivo el cerramiento de muro-cortina y la línea curva de la fachada, elementos ambos que definen el edificio. Asimismo hay que destacar el empleo decorativo de los diferentes materiales de revestimiento y el contraste entre la base del edificio y la parte superior, de muy distinta concepción desde el punto de vista del diseño. La segunda de ellas aprovecha con fines simbólicos el emplazamiento del edificio en cuanto a su fachada principal armonizándolo con una distribución en torno a un patio interior ajardinado, con predominio del color.

  9. Smooth vectors and Weyl-Pedersen calculus for representations of nilpotent Lie groups

    OpenAIRE

    Beltita, Ingrid; Beltita, Daniel

    2009-01-01

    We present some recent results on smooth vectors for unitary irreducible representations of nilpotent Lie groups. Applications to the Weyl-Pedersen calculus of pseudo-differential operators with symbols on the coadjoint orbits are also discussed.

  10. Review: Holger Stoecker: Afrikawissenschaften in Berlin von 1919 bis 1945. Zur Geschichte und Topographie eines wissenschaftlichen Netzwerkes (2008 Buchbesprechung: Holger Stoecker: Afrikawissenschaften in Berlin von 1919 bis 1945. Zur Geschichte und Topographie eines wissenschaftlichen Netzwerkes

    Directory of Open Access Journals (Sweden)

    Katrin Bromber

    2009-05-01

    Full Text Available Review of the monograph: Holger Stoecker: Afrikawissenschaften in Berlin von 1919 bis 1945. Zur Geschichte und Topographie eines wissenschaftlichen Netzwerkes, Stuttgart: Franz Steiner Verlag 2008, ISBN 978-3-515-09161-9, 359 pages. Besprechung der Monographie: Holger Stoecker: Afrikawissenschaften in Berlin von 1919 bis 1945. Zur Geschichte und Topographie eines wissenschaftlichen Netzwerkes, Stuttgart: Franz Steiner Verlag 2008, ISBN 978-3-515-09161-9, 359 Seiten.

  11. Miljonitehing : Kalev müüdud - jumal tänatud, kõik murest lahti / Andres Reimer, Holger Roonemaa, Vallo Toomet

    Index Scriptorium Estoniae

    Reimer, Andres

    2007-01-01

    Kalevi ja Tere toiduainetööstusettevõtete müügist investeerimisfirmale Alta Capital Partners. Vt. samas: Alta Capital Partners; Holger Roonemaa, Kristjan Jõevere. Finantsinspektsioon: Kalev rikkus head tava

  12. Height-integrated Pedersen and Hall conductivity patterns inferred from the TIROS-NOAA satellite data

    International Nuclear Information System (INIS)

    Fuller-Rowell, T.J.; Evans, D.S.

    1987-01-01

    The series of polar-orbiting National Oceanic and Atmospheric Administration spacecraft TIROS, NOAA 6, and NOAA 7 have been monitoring the particle influx into the atmosphere since late 1978. This data base has been used to construct statistical global patterns of height-integrated Pedersen and Hall conductivities for a discrete set of auroral activity ranges. The observations of energy influx and ''characteristic electron energy'' have been binned in a 1 0 latitude and 2 0 magnetic local time grid and ordered by an auroral activity index. This index is an estimate of the energy deposited into a single hemisphere by incident particles, a parameter generated directly from the particle observations and, therefore, internally consistent with the statistical patterns that are constructed. An average electron spectrum is associated with each characteristic energy, which enables a height profile of ionization rate in the upper atmosphere to be determined. The use of a pressure coordinate system insures that the normalized ionization rate profiles are independent of atmospheric model parameters. To create the statistical pattern of height-integrated conductivities, however, vertical profiles of atmospheric temperature and composition are assumed, and the ion density enhancements are evaluated from a chemical balance between ion production and recombination based on an ''effective'' recombination coefficient. The data base can also provide the statistical pattern of particle heating rates and ionization rates over a three-dimensional grid suitable as input to more sophisticated ionospheric and neutral thermospheric codes. copyright American Geophysical Union

  13. F-region Pedersen conductivity deduced using the TIMED/GUVI limb retrievals

    Directory of Open Access Journals (Sweden)

    Y. Zhang

    2006-07-01

    Full Text Available As a proxy of the Rayleigh-Taylor instability growth rate for equatorial plasma bubbles, we investigate the flux-tube integrated F-region Pedersen conductivity (ΣPF using the electron density profiles (EDPs provided by the Global Ultraviolet Imager (GUVI on board the Thermosphere Ionosphere and Mesosphere Energetics and Dynamics (TIMED satellite. The investigation is conducted using the EDPs obtained in the Atlantic sector at 19:00-22:00 LT during 4–17 August and 6-16 December 2002. The seasonal difference of the strength and location of the equatorial ionization anomalies (EIAs induces a significant difference in the deduced ΣPF. Much stronger EIAs are created at higher altitudes and latitudes in December rather than in August. At 19:00–20:00 LT, the peak value of the ΣPF has 23 mhos at 1100 km apex height during 14–16 December and 18mhos at 600 km during 15–17 August. The ΣPF decreases as local time progresses. Therefore, ΣPF provides a preferred condition for the growth of bubbles to higher altitudes at 19:00-20:00 LT than at later hours, in December rather than in August in the Atlantic sector.

  14. The Pedersen current carried by electrons: a non-linear response of the ionosphere to magnetospheric forcing

    Directory of Open Access Journals (Sweden)

    S. C. Buchert

    2008-09-01

    Full Text Available Observations by the EISCAT Svalbard radar show that electron temperatures Te in the cusp electrojet reach up to about 4000 K. The heat is tapped and converted from plasma convection in the near Earth space by a Pedersen current that is carried by electrons due to the presence of irregularities and their demagnetising effect. The heat is transfered to the neutral gas by collisions. In order to enhance Te to such high temperatures the maximally possible dissipation at 50% demagnetisation must nearly be reached. The effective Pedersen conductances are found to be enhanced by up to 60% compared to classical values. Conductivities and conductances respond significantly to variations of the electric field strength E, and "Ohm's law" for the ionosphere becomes non-linear for large E.

  15. Christian Bergqvist, Vladimir Bastidas, Henrik Ballebye Okholm, Torben Thorø Pedersen, Eirik Østerud: Where Do We Stand on Discounts? - A Nordic Perspective

    DEFF Research Database (Denmark)

    Fejø, Jens

    2018-01-01

    Anmeldelse af: Christian Bergqvist (red.), Vladimir Bastidas, Henrik Ballebye Okholm, Torben Thorø Pedersen & Eirik Østerud: Where Do We Stand on Discounts? - A Nordic Perspective. ExTuto Publishing, 2017. 208 sider, indbundet. Pris: 395 kr.......Anmeldelse af: Christian Bergqvist (red.), Vladimir Bastidas, Henrik Ballebye Okholm, Torben Thorø Pedersen & Eirik Østerud: Where Do We Stand on Discounts? - A Nordic Perspective. ExTuto Publishing, 2017. 208 sider, indbundet. Pris: 395 kr....

  16. Avaliação da atividade anti-inflamatória intestinal de Pfaffia glomerata (Spreng.) Pedersen

    OpenAIRE

    Tanimoto, Alexandre [UNESP

    2013-01-01

    Pfaffia glomerata (Spreng.) Pedersen (“ginseng brasileiro”) é uma planta medicinal que apresenta um amplo espectro de usos como tônico, antiestresse e afrodisíaco. Esta espécie pertence ao complexo grupo de plantas medicinais conhecidas como “ginseng” e compõe um grupo específico de plantas denominadas adaptógenas, definidas como produtos capazes de aumentar a resistência não específica do organismo frente a diferentes estímulos estressores; considerando-se tal definição, é previsível que os ...

  17. ST5 Observations of the Imbalance of Region 1 and 2 Field-Aligned Currents and Its Implication to the Cross-Polar Cap Pedersen Currents

    Science.gov (United States)

    Le, Guan; Slavin, J. A.; Strangeway, Robert

    2011-01-01

    In this study, we use the in-situ magnetic field observations from Space Technology 5 mission to quantify the imbalance of Region 1 (R1) and Region 2 (R2) currents. During the three-month duration of the ST5 mission, geomagnetic conditions range from quiet to moderately active. We find that the R1 current intensity is consistently stronger than the R2 current intensity both for the dawnside and the duskside large-scale field-aligned current system. The net currents flowing into (out of) the ionosphere in the dawnside (duskside) are in the order of 5% of the total R1 currents. We also find that the net currents flowing into or out of the ionosphere are controlled by the solar wind-magnetosphere interaction in the same way as the field-aligned currents themselves are. Since the net currents due to the imbalance of the R1 and R2 currents require that their closure currents flow across the polar cap from dawn to dusk as Pedersen currents, our results indicate that the total amount of the cross-polar cap Pedersen currents is in the order of 0.1 MA. This study, although with a very limited dataset, is one of the first attempts to quantify the cross-polar cap Pedersen currents. Given the importance of the Joule heating due to Pedersen currents to the high-latitude ionospheric electrodynamics, quantifying the cross-polar cap Pedersen currents and associated Joule heating is needed for developing models of the magnetosphere-ionosphere coupling.

  18. Nitrogênio e fósforo no crescimento de plantas de ginseng brasileiro [Pfaffia glomerata(Spreng. Pedersen] cultivadas in vitro Nitrogen and phosphorus on growth of brazilian ginseng [Pfaffia glomerata (Spreng. Pedersen] in vitro cultured plants

    Directory of Open Access Journals (Sweden)

    Denise Russowski

    2003-02-01

    Full Text Available O ginseng brasileiro [Pfaffia glomerata (Spreng. Pedersen] apresenta propriedades medicinais marcantes e, por isso, atualmente, é largamente explorado de forma extrativista, tanto por parte dos coletores de ervas como pela indústria farmacêutica. Este trabalho objetivou caracterizar o efeito da variação isolada da concentração de N e P do meio MS no crescimento de plantas de P. glomerata cultivadas in vitro. Segmentos nodais de 1,0cm de comprimento e sem folhas, de plantas já estabelecidas in vitro, foram cultivados em meio MS contendo cinco concentrações (0, 25, 50, 100 e 150% da concentração padrão do meio de cultura MS de nitrogênio ou fósforo. Aos 15 dias após a inoculação (DAI, o número de raízes e o percentual de enraizamento são maiores na concentração de N e P equivalentes a 50% daquela do meio de cultura MS. Aos 40 DAI, o crescimento em altura das brotações, número de segmentos nodais, índice de área foliar, número de folhas, matéria seca de raízes, da parte aérea e total da planta é maior na concentração de N e P, em média, próxima a 80% daquela do meio de cultura MS.Brazilian ginseng [Pfaffia glomerata (Spreng. Pedersen] has expressionable medicinal properties, and therefore, nowadays it is extensively exploited either by the herb collectors as well as the pharmaceutical industry. The aim of this work was to characterize the effect of N and P concentrations from the MS medium on growth of P. glomerata in vitro cultured plants. 1-node segment without leaves, from in vitro cultivated plants, were grown on five levels (0, 25, 50, 100, and 150% of the strength of the MS medium of N and P. After 15 days of inoculation, root number and rooting percentage are greater on N and P levels of the MS medium with 50% strength. After 40 days of inoculation, growth, based on sprout height, number of nodal segments per plant, leave area index per plant, number of leaves per plant, dry weight of aerial parts, roots

  19. 700 kg jern med de smukkeste krystaller

    DEFF Research Database (Denmark)

    Pedersen, Jens Olaf Pepke

    2017-01-01

    Anmeldelse af Holger Pedersen, “Pallas Iron – Russia’s first meteorite”, 260 sider, 190 kr. BoD 2017 (www.bod.dk/bog/).......Anmeldelse af Holger Pedersen, “Pallas Iron – Russia’s first meteorite”, 260 sider, 190 kr. BoD 2017 (www.bod.dk/bog/)....

  20. Comment on "Lack of enhanced preservation of organic matter in sediments under the oxygen minimum on the Oman Margin" by T.F. Pedersen, G.B. Shimmield, and N.B. Price

    Digital Repository Service at National Institute of Oceanography (India)

    Paropkari, A.L.; Mascarenhas, A.; PrakashBabu, C.

    and THIERSTEIN, 1987) and high primary productivity ( CALVERT, 1987; PEDERSEN and CALVERT, 1990). Since the Arabian Sea is a classic region to test these hypothesis, PAROPKARI et al. ( 199 1, 1992) also considered over 600 samples from the western Indian... is just the reverse. The shelf and the lower slope sediments are poor in organic content and the slope sediments do not contain appreciably high organic carbon as compared to the western Indian Margin, where primary productivity is com- paratively low...

  1. Sacarose e período de cultivo in vitro na aclimatização ex vitro de ginseng brasileiro (Pfaffia glomerata Spreng. Pedersen Sucrose and duration of in vitro growth on ex vitro acclimatization of Brazilian ginseng (Pfaffia glomerata Spreng. Pedersen

    Directory of Open Access Journals (Sweden)

    Etiane Caldeira Skrebsky

    2004-10-01

    Full Text Available Pfaffia glomerata (Spreng. Pedersen é uma planta extensivamente usada na medicina popular em decorrência de possuir propriedades fitoterápicas. Devido à sua baixa capacidade fotossintética, as plantas cultivadas in vitro requerem uma fonte extra de carboidratos para suprir suas necessidades metabólicas. O tempo de cultivo in vitro influencia as taxas de crescimento das raízes e da parte aérea de P. glomerata. Este trabalho teve como objetivos avaliar os efeitos da sacarose e do período de cultivo in vitro na aclimatização ex vitro de plântulas de P. glomerata. Os tratamentos consistiram de uma combinação bifatorial (5x2 entre cinco concentrações de sacarose (15, 30, 45, 60 e 75g L-1 e dois períodos de cultivo in vitro (25 e 32 dias após a inoculação. No cultivo in vitro, a parcela experimental consistiu de um tubo de ensaio contendo 10mL de meio MS e um segmento nodal, obtidos de plântulas mantidas in vitro, de 1,0cm de comprimento e sem folhas. O procedimento de aclimatização consistiu de quatro fases sucessivas de cultivo ex vitro: (i abertura dos tubos de ensaio e exposição das plântulas ao ambiente de câmara climatizada por três dias; (ii transplantio para substrato Plantmax e cultivo em condições de câmara climatizada por 21 dias; (iii transferência das mudas para ambiente natural parcialmente sombreado, com duração de 24 dias; e (iv transplantio para solo em condições de cultivo a campo. O maior crescimento das plantas obtido pelo aumento da disponibilidade de sacarose (concentrações entre 45 e 60g L-1 no cultivo in vitro contribuiu para a aclimatização. Independente do período de retirada das plantas do cultivo in vitro, as mudas obtiveram adequada aclimatização. O procedimento de aclimatização foi 100% eficiente na produção de mudas de P. glomerata.Pfaffia glomerata (Spreng. Pedersen is an extensively used plant in popular medicine due to its phytotherapic characteristics. Due to low

  2. Loomingu Raamatukogu aasta 1995 / Holger Kaints

    Index Scriptorium Estoniae

    Kaints, Holger, 1957-

    1996-01-01

    Järg: 29. märts 1996, lk. 15. Rets. rmt.: Jerzy Kosinski 'Kirgas lind' (nr.18-20); Yasar Kemali 'Madu maha tappa!' (nr.24); Lisa St. Aubin de Terani 'Koja valvurid' (nr.15-17); Gabriel Garcia Marquezi 'Väljakuulutatud mõrva kroonika' (nr.11/12); Arthur Koestleri 'Keskpäevapimedus' (nr.31-34) ja 'Pühendatud' (nr.5); Heinrich Bölli 'Katharina Blumi kaotatud au' (nr.22/23); Marina Palei 'Ringkanali Cabiria' (nr.14); Graham Greene'i 'Armastusloo lõpp' (nr.25-27); Henry Jamesi 'Asperni kirjad' (nr.37/38); Truman Capote'i 'Sünnipäevalapsed' (nr.8/9); Antonio Tabucchi 'Taevarand' (nr.21); Michael Bullocki 'Kaev ja teisi jutte' (nr.3); Henry Milleri 'Naeratus redeli jalamil' (nr.10); Arto Paasilinna 'Jänese aasta' (nr.28-30); Kahlil Gibrani 'Prohvet' (nr.4); Rainer Maria Rilke 'Kirjad noorele luuletajale (nr.13); Jaan Kaplinski 'Jää ja Titanic' (nr.6/7); Rein Saluri 'Tobukesed' (nr.36); Kaksteist Eesti kirja (nr.1/2); Hermann Hesse 'Fantaasiad' (nr.35); Herman Lindqvisti 'Üks Euroopa puha' (nr.39/40)

  3. Architecture student Meredith Baber wins Kohn Pedersen Fox Traveling Fellowship

    OpenAIRE

    Chadwick, Heather Riley

    2009-01-01

    Meredith Baber of Cartersville, Va., a fourth-year honors architecture student in the School of Architecture + Design, is the first student in the history of Virginia Tech to win a prestigious Kohn Pederson Fox (KPF) Associates Travelling Fellowship.

  4. Hypnotic effect of ecdysterone isolated from Pfaffia glomerata (Spreng. Pedersen

    Directory of Open Access Journals (Sweden)

    Raquel Fenner

    Full Text Available In this study the depressant effect of fractions from P. glomerata was initially evaluated using the mice barbiturate sleeping time test as reference. The fractions tested were the CHCl3, the EtOAc, the n-BuOH and the aqueous fraction obtained from P. glomerata subterraneous parts. Only the pretreatment with the lipophilic fraction (CHCl3: EtOAc, 1:1, w/w increased the barbiturate sleeping time (i.p 500 mg/kg; v.o. 1000 mg/kg. Ecdysterone, the main substance isolated from this lipophilic fraction, was identified by spectroscopic methods and its content in the ethanol extract was determined as 1.4% (w/w by HPLC. In order to investigate the hypothesis of ecdysterone displaying a depressant effect on nervous central system, an evaluation toward the hypnotic-sedative and anxiolytic effects of this drug was carried out. Ecdysterone 100 mg/kg, i.p, increased the barbiturate sleeping time without provoking hypothermia; when administered by oral route its minimal effective dose was 400 mg/kg. On the other hand, ecdysterone (100 mg/kg, i.p; 400 mg/kg, p.o did not impair motor coordination and was ineffective on pentylenetetrazole-induced convulsion, elevated plus-maze and step-down inhibitory avoidance tests, indicating that at these doses the drug does not present an anxiolytic profile and does not cause manifest neurotoxic effects as well. In conclusion, the lipophilic fraction from P. glomerata presents a hypnotic effect being ecdysterone one of the compounds responsible for this CNS activity.

  5. Eesti tankivalikud: Abrams või Leopard 2 / Holger Roonemaa

    Index Scriptorium Estoniae

    Roonemaa, Holger

    2010-01-01

    Ametlikku otsust kaitseväele tankide ostmiseks veel ei ole, kuid kui Eesti kaitsevägi asub tanke ostma, siis tõenäoliselt hakatakse valima Leopard 2 ja Abrams vahel. Tankidega seotud kuludest ja olukorrast Norras

  6. Siim Kallas kohtus California kuberneri Schwarzeneggeriga / Holger Roonemaa

    Index Scriptorium Estoniae

    Roonemaa, Holger

    2008-01-01

    Euroopa Komisjoni asepresident Siim Kallas käis visiidil USA-s Silicon Valleys tutvumas maailma suuremate infotehnoloogiafirmadega. Kallase sõnul peaksid ambitsioonidega Eesti ettevõtetel kindlasti olema sidemed ka Silicon Valleys. Henrik Hololei arvamus

  7. Bushi visiidi kasu Eestile : viisavabadus ja õhuruumi turve / Holger Roonemaa

    Index Scriptorium Estoniae

    Roonemaa, Holger

    2006-01-01

    Peaminister Andrus Ansip tõstatas kohtumisel USA presidendi George W. Bushiga viisavabaduse ja õhuturbe teema. G. W. Bushi ja Mart Laari kohtumisest. Vt. samas: Bush mõtleb oma poliitilisele pärandile; Bush kohtus Iraagis vigastada saanuga; Politseinik Purik: Bush oli fantastiliselt kihvt; Mati Raidma: Bush oli Eesti asjadega hästi kursis; Lisad: Bush oli hea suhtluspartner; Mis president Bushile Eestis meeldis? Vt. samas lk. 6-7 Anneli Ammas. Kohtumine maailma tähtsaima mehega ehk reportaaž turvamulli seest

  8. Isolation and prebiotic activity of inulin-type fructan extracted from Pfaffia glomerata (Spreng) Pedersen roots.

    Science.gov (United States)

    Caleffi, Edilainy Rizzieri; Krausová, Gabriela; Hyršlová, Ivana; Paredes, Larry Ladislao Ramos; dos Santos, Marcelo Müller; Sassaki, Guilherme Lanzi; Gonçalves, Regina Aparecida Correia; de Oliveira, Arildo José Braz

    2015-09-01

    Pfaffia glomerata (Amaranthaceae) is popularly known as "Brazilian ginseng." Previous studies have shown that fructose is the major carbohydrate component present in its roots. Inulin-type fructans, polymers of fructose, are the most widespread and researched prebiotics. Here, we isolated and chemically characterized inulin extracted from P. glomerata roots and investigated its potential prebiotic effect. Fructans were isolated and their structures were determined using colorimetric, chromatography, polarimetry, and spectroscopic analysis. The degree of polymerization (DP) was determined, and an in vitro prebiotic test was performed. The structure of inulin was confirmed by chromatography and spectroscopic analysis and through comparison with existing data. Representatives from the genera Lactobacillus and Bifidobacterium utilized inulin from P. glomerata, because growth was significantly stimulated, while this ability is strain specific. The results indicated that inulin extracted from P. glomerata roots represents a promising new source of inulin-type prebiotics. Copyright © 2015 Elsevier B.V. All rights reserved.

  9. Efeito hipinótico de ecdisterona isolada de Pfaffi a glomerata (Spreng.) Pedersen

    OpenAIRE

    Fenner, Raquel; Zimmer, Aline Rigon; Neves, Gilda Angela; Kliemann, Michele Patricia; Gosmann, Grace; Rates, Stela Maris Kuze

    2008-01-01

    Neste trabalho foi avaliado, em roedores, o efeito depressor das frações clorofórmio (CHCl3), acetato de etila (EtOAc) e n-butanol, obtidas das partes subterrâneas de Pfaffi a glomerata, empregando-se o teste de tempo de sono barbitúrico como referência. Somente a fração lipofílica (CHCl3:EtOAc, 1:1, m/m) (i.p. 500 mg/kg; v.o. 1000 mg/kg) potenciou o tempo de sono induzido por pentobarbital. A ecdisterona foi isolada e identifi cada como constituinte majoritário (1,4% m/m) desta fração, atrav...

  10. Toomas Annus : peame kõigeks valmis olema / Toomas Annus ; interv. Anneli Ammas, Holger Roonemaa

    Index Scriptorium Estoniae

    Annus, Toomas, 1960-

    2007-01-01

    Altkäemaksu andmises ja usalduse kuritarvitamises kahtlustatav Merko Ehituse nõukogu esimees vastab muu hulgas küsimustele, kui sageli ta Villu Reiljani, Ester Tuiksoo jt. Rahvaliidu poliitikutega aastatel 2004-2006 kohtus, milliseks ta hindab selle mõju Merko aktsiale, et kaitsepolitsei teda kahtlustab. Lisa: Reiljan kuulatakse üle lähiajal

  11. Carl Bildt : Gruusia edu põhineb Eesti eeskujul / Carl Bildt ; interv. Holger Roonemaa

    Index Scriptorium Estoniae

    Bildt, Carl, 1949-

    2006-01-01

    Rootsi välisminister peab Gruusia puhul kõige tähtsamaks reformide jätkumist. Venemaal ja Gruusial tuleks oma erimeelsustest üle saada, EL ootab Venemaalt kinnitust Gruusia territoriaalse puutumatuse kohta. Vene-Saksa gaasijuhtme rajamisel teeb Rootsile muret peamiselt selle projekti keskkonnaohtlikkus

  12. Afganistan vajab liitlasvägede abi veel aastaid / Holger Roonemaa

    Index Scriptorium Estoniae

    Roonemaa, Holger

    2007-01-01

    Kuigi liitlasväed tegutsevad Afganistanis juba märksa laiemal alal kui aastaid tagasi, on koalitsioonivägede kohalolek veel aastaid riigile vajalik. Taliban jätkab aktiivset vastupanu ning on alustanud ka infosõda. Kaart. Lisa: Võitlus südamete ja mõistuse pärast; Oopiumitoodang suureneb

  13. Cowan: Eesti mereväelaev seilab esmakordselt Vahemerel / Holger Roonemaa

    Index Scriptorium Estoniae

    Roonemaa, Holger

    2008-01-01

    Eesti miinijahtija "Admiral Cowan" viibimisest NATO reageerimisjõudude koosseisus Vahemeres. Päevalehel õnnestus koos Admiral Cowani meeskonnaga kaasa teha 595.2 meremiili pikkune sõit Toulonist Sitsiilia Augusta sadamasse. Autori muljed

  14. Stan's Cafe tõi publiku näole laia naeratuse / Holger Roonemaa

    Index Scriptorium Estoniae

    Roonemaa, Holger

    2002-01-01

    Rakvere seitsmenda rahvusvahelise teatrifestivali Baltoscandal üks omapärasemaid esinejaid oli Birminghamist pärit teatrikompanii Stan's Cafe, mis mängis oma etendust "See on sinu film" (It's Your Film") korraga ainult ühele vaatajale

  15. Alar Laneman siirdub USA-sse kaitseatašeeks / Holger Roonemaa

    Index Scriptorium Estoniae

    Roonemaa, Holger

    2007-01-01

    Brigaadikindral Alar Lanemanist võib saada Eesti kaitseatašee USA-s. Endise kaitseministri Jürgen Ligi sõnul oli A. Laneman osaline mitmetes juhtimisvigades ning neist ühe puhul kestab senini kriminaalasi

  16. Päevaleht Afganistanis : rahvusliku armee roll suureneb pidevalt / Holger Roonemaa

    Index Scriptorium Estoniae

    Roonemaa, Holger

    2007-01-01

    Afganistani rahvuslik armee suureneb kiiresti, sest armees teenimine tagab kindla sissetuleku. Kindral Gul Aqa Nahib kiidab armee koostööd Eesti ja Briti sõduritega, tema hinnangul hakkab Talibani jõud raugema. Lisa: Luksuslik baas

  17. 19 February 2015 - Professor Holger Hanselka President Karlsruhe Institute of Technology Federal Republic of Germany

    CERN Multimedia

    Gadmer, Jean-Claude

    2015-01-01

    visiting the CMS cavern with CMS Collaboration Deputy Spokesperson K. Borras and CMS Collaboration, Team Leader, Karlsruhe Institut fur Technologie T. Muller and signing the Guest book with CERN Director-General R. Heuer. C. Schaefer present throughout.

  18. Johannes Hint : ühe XX sajandi ausa mehe tragöödia / Holger Kaljulaid

    Index Scriptorium Estoniae

    Kaljulaid, Holger

    2006-01-01

    Desintegraatori juhi Johannes Hindi tegevusest ning temaga seotud kohtuprotsessist meedias avaldatud materjalide ja arhiividokumentide põhjal. Vt. samas väljavõtteid: Vladimir Georg Karassev-Orgusaare mõtteavaldusest 1982. aasta jaanuaris RL-i stuudios Pariisis; Johhannes Hindi sõnavõtust NSV Liidu Riikliku Plaanikomitee (Gosplan) kolleegiumil 10. II 1981 ja tema tööst "Viimaseid mõtteid inimkonnale", 1985; Aleksander Kaelase mõtteavaldusest aprillis 1955 Ameerika Hääle saates; Nikolai Baibakovi, Gosplani kunagise juhi (1965-85) 2000. a. märtsis antud intervjuust

  19. Galojani kogutud paberid võivad varju heita ka Sinijärvele / Holger Roonemaa

    Index Scriptorium Estoniae

    Roonemaa, Holger

    2007-01-01

    Autori väitel andis Eesti Euroopa Liikumise (EEL) raamatupidaja Anna-Maria Galojanile kirjalikult teada, et mõned nõukogu esimehe Riivo Sinijärve esitatud andmed ei ole kooskõlas EEL-i tegevusega. Kiri esitati kaks päeva pärast seda, kui nõukogu oli Galojani EEL-i juhi kohalt tagasi kutsunud. Mõnedest EEL-i kulutustest enne Galojani saamist selle juhiks. R. Sinijärv põhjendab EEL-i laenuvõtmise vajadust ja Julianus Inkasso nõudeid

  20. Kaitseväelastel pole alust kogu missiooni eest lisapalka nõuda / Holger Roonemaa

    Index Scriptorium Estoniae

    Roonemaa, Holger

    2007-01-01

    Afganistanis teeninud kolm Eesti kaitseväelast nõuavad kaitseväelt Tallinna halduskohtus igaüks enam kui poolt miljonit krooni. Tööõigusbüroo Labour Consulting juristi Katrin Sarapi sõnul pole selliseks nõudeks alust. Vt. samas: Rahanõudjad teenivad edasi

  1. Audit : Galojan kulutas kolme kuuga toidule 56 000 krooni / Holger Roonemaa

    Index Scriptorium Estoniae

    Roonemaa, Holger

    2008-01-01

    MTÜ Eesti Euroopa Liikumine erakorraline üldkoosolek otsustas esitada liikumise endisele juhile Anna-Maria Galojanile 817 000 krooni suuruse nõude, auditi tulemuste kohaselt kõrvaldas eksjuht liikumise raha ligi 950 000 krooni eest

  2. Välisminister Urmas Paet : Kosovo tunnustamine on ainult aja küsimus / Holger Roonemaa

    Index Scriptorium Estoniae

    Roonemaa, Holger

    2008-01-01

    Välisminister Urmas Paet ei nimetanud veel kuupäeva, millal Eesti tunnustab Kosovo iseseisvust. Ta ei näe Kosovo iseseisvuse tunnustamisel vastuolu ÜRO resolutsiooniga, mis sätestab endise Jugoslaavia ja praeguse Serbia territooriumi terviklikkuse

  3. IT-firmad pääsevad pooleks aastaks Silicon Valleysse / Holger Roonemaa

    Index Scriptorium Estoniae

    Roonemaa, Holger

    2010-01-01

    Tehnopol ja EAS toetavad nn. start-up-firmade saatmist pooleks aastaks USA-sse Silicon Valleysse kogemusi omandama, programm on mõeldud eelkõige neile ettevõtetele, kel on oma toode või teenus valmis ja kes soovivad sellega maailmaturule minna

  4. Ekspert : mobiil-ID kasutamine valimistel turvariske ei tekita / Holger Roonemaa

    Index Scriptorium Estoniae

    Roonemaa, Holger

    2008-01-01

    E-valimiste projektijuhi Taavi Martensi väitel pole põhjust kahelda mobiil-ID turvalisuses. Valimiskomisjoni esimehe Heiki Sibula meelest peaks m-ID kaarte välja andma kodakondsus- ja migratsiooniamet

  5. Üle tuhande inimese pangakaardid suleti kopeerimise tõttu / Holger Roonemaa, Aivar Pau

    Index Scriptorium Estoniae

    Roonemaa, Holger

    2007-01-01

    Viimastel päevadel on pangad sulgenud üle tuhande pangakaardi, sest avastati, et Tabasalu bensiinijaama makseautomaadis olnud seade salvestas kaartide PIN-koode ning kopeeris pangaandmeid. Vt. samas: Kliendid avastasid kaartide sulgemise alles maksmisel

  6. Briti suursaadik: koostöö sujub / Nigel Haywood ; interv. Holger Roonemaa

    Index Scriptorium Estoniae

    Haywood, Nigel, 1955-

    2007-01-01

    Briti suursaadik Eestis vastab küsimustele, mis juhtus, et Eesti luurajad Afganistanis ei saa enam tööd teha, kas suursaadiku meelest on veel võimalik, et Eesti luurajad võiksid töötada välismissioonil Suurbritannia alluvuses, kas segadus Eesti luurajatega ei või jätta vimma Eesti ja Briti kaitseametnike vahele

  7. Enraizamento e germinação na propagação de Pfaffia glomerata (Spreng. Pedersen (ginseng-brasileiro Rooting and germination in propagation of Pfaffia glomerata (Spreng. Pedersen (ginseng-brasileiro

    Directory of Open Access Journals (Sweden)

    Silvana de Paula Quintão Scalon

    2009-10-01

    Full Text Available Conduziu-se este trabalho, com o objetivo de avaliar a propagação sexuada e assexuada de Pfaffia glomerata (ginseng brasileiro. As sementes foram pré-embebidas por 24 horas em KNO3 1%; ácido giberélico 50, 100 e 200 mg L-1 ; emágua e as sementes que não receberam tratamento serviram como testemunha. A semeadura foi em placas de petri sobre duas folhas de papel de filtro e a incubação a 25ºC, sob iluminação constante e na ausência de luz. As estacas com º15 cm foram imersas durante 6 horas em IAA 250 e IBA 500 mg L-1, ácido bórico 1% e em água e plantadas em embalagem plástica, contendo terra+areia (1:1. O primeiro experimento foi conduzido em delineamento inteiramente casualizado em esquema fatorial 2 (níveis de luz x 6 (tratamento de pré-embebição em 4 repetições de 20 sementes. O segundo em DIC com 5 tratamentos, 4 repetições de 15 estacas por repetição. As sementes de ginseng brasileiro necessitam de tratamento de pré-embebição para acelerar a germinação, sendo a imersão em KNO3 o método mais eficiente, proporcionando 63% de germinação. Apresentam fotoblastismo neutro, com germinação média de 45%. As estacas de ginseng brasileiro imersas apenas em água apresentaram 100% de enraizamento, maior número de brotos (2,5 e maior comprimento de raiz (8,6 cm. A espécie apresenta potencial para ambos os métodos de propagação.The objective of this study was to evaluate sexual and asexual propagation of Pfaffia glomerata (Brazilian Ginseng. The seeds were pre-soaked for 24 hours in KNO3 1% , gibberellic acid 50, 100, 200 mg L-1 , and in water. Untreated seeds served as control. Sowing was accomplished in petri dishes on 2 sheets of filter paper, at 25ºC incubation, under constant illumination, and in the absence of light. The cuttings with º1,5 cm were immersed for 6 hours in IAA 250 and 500mg L-1, boric acid1% ,and in water. Soon after they were planted in plastic containers with soil + sand (1:1. The first experiment was in factorial design 2 (light levels x 6 (pre-soak treatment in 4 repetitions of 20 seeds per repetition. The second in ERD in 5 treatments, 4 repetitions of 15 cuttings per repetition. Brazilian Ginseng seeds need pre-soak treatment to accelerate germination. We found immersion in KNO3 the most efficient method, providing 63% germination. They presented neuter photoblastism with an average germination of 45%. The Brazilian Ginseng cuttings immersed in water presented 100% rooting, a higher number of sprouts (2,5, and greater length (8,6 cm. The species presents potential for both propagation methods.

  8. Changes in root morphology and dry matter production in Pfaffia glomerata (Spreng. Pedersen accessions in response to excessive zinc

    Directory of Open Access Journals (Sweden)

    K. BERNARDY

    Full Text Available ABSTRACT Zinc (Zn participates of numerous metabolic processes in plants. However, it can become toxic to plants in excessive concentrations in the soil. Pfaffia glomerata is a Brazilian medicinal species that has stood out because of its numerous chemical and functional properties, mainly by the triterpene saponins and ecdysteroids accumulated in its roots. This study aimed to evaluate the effects of zinc excess on many root morphological parameters of Pfaffia glomerata. A 4 x 3 factorial design was employed in a completely randomized scheme with 3 replicates. The treatments consisted of four concentrations of Zn (2, 100, 200, and 300 µM and three accessions of P. glomerata (BRA, GD, and JB grown in a hydroponic system for 7 and 14 days. Differences in root morphology and dry mass production were observed among the three accessions in response to excessive Zn. Some growth parameters of GD accession increased with the addition of Zn, ranging from 36 to 79 µM. However, the GD and JB accessions presented reduction in dry mass production, root area, length, and volume with increasing Zn levels. The BRA accession, which had the lowest growth among accessions, presented chlorotic leaves. The shoot/root dry mass ratio and root diameter increased linearly for BRA and GD accessions at 7 days. Based on the evaluated parameters, we observed the following order of Zn excess tolerance in P. glomerata accessions: GD> JB> BRA.

  9. Stratfori analüütik Sean Noonan: taktikaliselt suri Osama juba ammu / Sean Noonan ; intervjueerinud Holger Roonemaa

    Index Scriptorium Estoniae

    Noonan, Sean

    2011-01-01

    Stratfori analüütiku hinnangul nähakse araabia maades Osama bin Ladeni surmas tõenäoliselt märtrisurma. Lähiajal võib toimuda väga algelisi kättemaksuüritusi, keskplaanis tõenäoliselt toimub suurem radikaliseerumine. Bin Ladeni tapmine annab USA presidendile rohkem motivatsiooni õigustada Afganistanist lahkumist

  10. Who Gets into Government? Coalition Formation in European Democracies / Holger Döring, Johan Hellström

    Index Scriptorium Estoniae

    Döring, Holger

    2013-01-01

    Valitsuste formeerumise erinev dünaamika 26 euroopa demokraatias (sealhulgas Eesti). Esimene valitsuses osalemise otsustavate tegurite süstemaatiline võrdlus ja erinevused Ida- ja Lääne-Euroopa riikide vahel

  11. USA suursaadik : Eesti peaks meedia tähelepanu ära kasutama / Stanley Davis Phillips ; interv. Holger Roonemaa

    Index Scriptorium Estoniae

    Phillips, Stanley Davis

    2007-01-01

    USA suursaadik räägib Tõnismäe pronkssõdurist, viisavabaduse võimalikkusest Eesti ja USA vahel, suursaadiku plaanidest Eestis, president Toomas Hendrik Ilvese eelseisvast kohtumisest USA presidendi George W. Bushiga, USA ja Venemaa suhetest, Iraagi sõjast ning kommenteerib ühe USA presidendikandidaadi Pat Buchanani väidet, et USA jaoks oleks absurdne astuda sõtta näiteks Venemaaga, et kaitsta Eestit. Suursaadik soovitab Eestil aktiivselt ära kasutada Venemaa-poolsete küberrünnakutega kaasnenud meediakajastust. Ilmunud ka: Vaba Eesti Sõna 7. juuni 2007, lk. 10; ingl. k. Eesti Elu 8. juuni 2007, lk. 8-9, pealk.: U.S Ambassador: Estonia should take advantage of media attention

  12. Harju maakohus saab Herman Simmi "nimelise" istungitesaali / Holger Roonemaa ; intervjueerinud Jan Jõgis-Laats ; kommenteerinud Andrus Ansip

    Index Scriptorium Estoniae

    Roonemaa, Holger

    2009-01-01

    Tingimustest turvaalale, kus töödeldakse riigisaladusi ja Harju maakohtu istungisaali vastavusest nendele Herman Simmi kohtuasja arutamiseks. Vt. samas lühiinterv.: Ansip: Simm pole meie James Bond

  13. Eesti üksused näitavad YouTube'is oma tegevust Afganistanis / Holger Roonemaa

    Index Scriptorium Estoniae

    Roonemaa, Holger

    2008-01-01

    Eesti kaitseväelased Iraagis on juba üle aasta näidanud oma tegevust internetis. Vanemleitnant Ingrid Mühlingu sõnul kaitsevägi videote avalikustamises üldjuhul probleemi ei näe, kuid alati tuleb arvestada, et video avaldamisega ei seataks ohtu enda ega kaasvõitlejate elu ja tervist

  14. Päikesereiside korraldajad tunnevad rõõmu aasta esimese poole tulemuste üle / Holger Roonemaa

    Index Scriptorium Estoniae

    Roonemaa, Holger

    2004-01-01

    Reisibüroode hinnangul on lõunamaareiside täituvus olnud 2004. aasta esimesel poolel väga hea ja tulenevalt sellest on suurenenud ka turismifirmade käive ning kasum. Kommentaarid Domina World Traveli, Horizon Traveli, Novatoursi ja Marhaba Toursi esindajatelt. Diagramm

  15. IT-visionäär Linnar Viik annaks igale põhikooliõpilasele sülearvuti / Holger Roonemaa

    Index Scriptorium Estoniae

    Roonemaa, Holger

    2006-01-01

    Linnar Viik peab vajalikuks anda kõigile üheksanda klassi õpilastele sülearvuti ning tekitada koolidesse WiFi leviala. Programmiga Külatee 3 eesmärk on tagada interneti püsiühendus hajusa asustusega maa-aladel, 2007. aastal hakkab traadita internetti pakkuma ka Televõrgu AS

  16. Validação da metodologia de quantificação espectrofotométrica das saponinas de Pfaffia glomerata (Spreng. Pedersen - Amaranthaceae

    Directory of Open Access Journals (Sweden)

    C.L.S. Vigo

    Full Text Available Realizou-se validação analítica espectrofotométrica das saponinas totais das raízes de Pfaffia glomerata. Em testes iniciais utilizou-se saponina Merck em cinco concentrações (0,08-0,28 mg/ml para obtenção da curva de calibração e verificação da linearidade, repetibilidade e reprodutibilidade. As raízes foram avaliadas em extratos hidroalcoólicos purificados com n-butanol. O reagente cromogênico escolhido foi Cloreto de Cobalto 0,2% em pico experimental em 284nm. O tempo de leitura ideal foi de 10-20 minutos após o início da reação. O método mostrou linearidade para a faixa de concentrações utilizadas (R²= 0,9963. A precisão (coeficientes de variação situou-se entre 7-12%, indicando boa reprodutibilidade. O limite de quantificação situou-se em 0,08 mg/ml e o limite de detecção em 0,02 mg/ml. A exatidão do procedimento forneceu erro relativo de 6,3; 3,4; 3,5; 1,8 e 0,3% para as concentrações utilizadas. Os dados da curva-padrão foram aplicados em várias amostras de raízes levando ao valor média de 13,5±2,0%. Os dados obtidos permitem a quantificação espectrofotométrica das saponinas totais das raízes de P. glomerata.

  17. Wesley Clark : uus külm sõda väga ebatõenäoline / Wesley Clark ; interv. Holger Roonemaa

    Index Scriptorium Estoniae

    Clark, Wesley

    2007-01-01

    Lennart Meri mälestuskonverentsil osalenud endine NATO vägede ülemjuhataja Eesti ja maailma julgeolekupoliitilisest olukorrast ning Venemaa, USA ja NATO positsioonist rahvusvahelistes suhetes. Lühielulugu

  18. Revisiting the left cabinet share: How to measure the partisan profile of governments in welfare state research / Holger Döring, Hanna Schwander

    Index Scriptorium Estoniae

    Döring, Holger

    2015-01-01

    Artiklis analüüsitakse poliitilise vasakpoolsuse võimu, täpsemalt on vaatluse all sotsiaaldemokraatide osakaal eri riikide (sh Eesti) valitsustes ning milline on selle mõju heaoluriigi kujunemisele ja poliitika tulemustele.

  19. Observing a Burst with Sunglasses

    Science.gov (United States)

    2003-11-01

    factor by which the lines in the spectrum of an object are shifted towards longer wavelengths. Since the redshift of a cosmological object increases with distance, the observed redshift of a remote galaxy also provides an estimate of its distance. [2]: Members of the team include Jochen Greiner, Arne Rau (Max-Planck-Institut für extraterrestrische Physik, Germany), Sylvio Klose, Bringfried Stecklum (Thüringer Landessternwarte Tautenburg, Germany), Klaus Reinsch (Universitätssternwarte Göttingen, Germany), Hans Martin Schmid (Institut für Astronomie Zürich, Switzerland ), Re'em Sari (California Institute of Technology, USA), Dieter H. Hartmann (Clemson University, USA), Chryssa Kouveliotou (NSSTC, Huntsville, Alabama, USA), Eliana Palazzi (Istituto di Astrofisica Spaziale e Fisica Cosmica, Bologna, Italy), Christian Straubmeier (Physikalisches Institut Köln, Germany), Sergej Zharikov, Gaghik Tovmassian (Instituto de Astronomia Ensenada, Mexico), Otto Bärnbantner, Christop Ries (Wendelstein-Observatorium München, Germany), Emmanuel Jehin, Andreas Kaufer (European Southern Observatory, Chile), Arne Henden (USNO Flagstaff, USA), Anlaug A. Kaas (NOT, La Palma, Spain), Tommy Grav (University of Oslo, N), Jens Hjorth, Holger Pedersen (Astronomical Observatory Copenhagen, Denmark), Ralph A.M.J. Wijers (Astronomical Institute Anton Pannekoek, Amsterdam, The Netherlands), Hye-Sook Park (Lawrence Livermore Nat. Laboratory, USA), Grant Williams (MMT Observatory, Tucson, USA), Olaf Reimer (Theoretische Weltraum- und Astrophysik Universität Bochum, Germany) [3]: When electrons - which are electrically charged - move through a magnetic field, they spiral around an axis defined by the local magnetic field. Electrons of high energy spiral very rapidly, at speeds near the speed of light. Under such conditions, the electrons emit highly polarised electromagnetic radiation. The intensity of this radiation is related to the strength of the magnetic field and the number and energy

  20. ALTAY LANGUAGES IN NOSTRATIK LANGUAGES THEORY NOSTRATİK DİL TEORİSİ İÇERİSİNDE ALTAY DİLLERİ

    Directory of Open Access Journals (Sweden)

    Ekrem ARIKOĞLU

    2009-12-01

    Full Text Available Nostratic language of the theory of names Holger Pedersen his paternity, İlliç Svıtiç theory developed by the Afro-Asiatic, Kartvel, Elam-Dravid, Indo-European, Ural-Yukagir, Eskimo-Aleut, Altai, Korea, the Japanese language group of the common historical roots a defense theory. According to the theory of our day with each other within the same family or language group are not considered languages, at an earlier date (14 -10 thousands BC was based on the same origin. 8 thousand years ago, was separated from the main group of the Altaic language group. But today, many elements of restructuring through leksic history helps to establish ties. Altaic languages or language groups, with the above-mentioned links between the evaluation of the studies, examples are given in words. These links have been limited to elements leksical notice. Nostratik dil teorisi, isim babalığını Holger Pedersen’in yaptığı ve İlliç Svitıç tarafından geliştirilen; Afro-Asyatik, Kartvel, Elam-Dravit, Hint-Avrupa, Ural-Yukagir, Eskimo-Aleut, Altay, Kore ve Japon dillerinin aynı kökene dayandığını savunan bir teoridir.Bu teoriye göre, günümüzdeki pek çok dil ailesi MÖ 14-10 bin yıllarında aynı kökene dayanıyordu. 8 bin yıl önce Altay dil grubu ana gruptan ayrıldı. Fakat günümüzde pek çok leksik unsur tarihî bağların tespit edilmesine yardımcı olmaktadır. Altay dilleri veya dil grubunun diğer dil aileleriyle olan bağları, örnek kelimelerle gösterilmektedir. Bu bağlantılar daha çok leksik unsurlarla sınırlı tutulmuştur.

  1. Borel reductibility and classification of von neumann algebras

    DEFF Research Database (Denmark)

    Sasyk, R.; Törnquist, Asger Dag

    2009-01-01

    We announce some new results regarding the classification problem for separable von Neumann algebras. Our results are obtained by applying the notion of Borel reducibility and Hjorth's theory of turbulence to the isomorphism relation for separable von Neumann algebras....

  2. Pop / Tõnu Kaalep

    Index Scriptorium Estoniae

    Kaalep, Tõnu, 1966-2018

    2002-01-01

    Heliplaatidest Holger Czukay "Linear City: Internet Audio Collabs". U-She & Holger Czukay "Time and Tide". The Breeders "Title TK". Jim Black "Splay". Gotan Project "La Revancha Del Tango". Robert Owens "Lowe Will Find Its Way". Green Velvet "Whatever". Alex Gopher with Demon presents "Wuz". Swan Lee "Enter"

  3. Lyset og livet

    DEFF Research Database (Denmark)

    Oxenvad, Carsten Michael

    2003-01-01

    Beskrivelse af Øster Aaby Friskole og friskoler generelt. Blandt bidragyderne: Susanne Eskildsen, Holger Henriksen, Margrethe Vestager, John Iversen, Thorstein Balle og Poul Erik Søe......Beskrivelse af Øster Aaby Friskole og friskoler generelt. Blandt bidragyderne: Susanne Eskildsen, Holger Henriksen, Margrethe Vestager, John Iversen, Thorstein Balle og Poul Erik Søe...

  4. Ammende pakub suvemuusikat / Silja Joon

    Index Scriptorium Estoniae

    Joon, Silja, 1966-

    2007-01-01

    Kontsertidest Pärnus Ammende villas: 5. juulil "Mõeldes Sinule" (Laura Põldvere, Jorma Toots, Marti Tärn, Ahto Abner), 12. juulil Kadri Voorand, Jürmo Eespere, Mihkel Mälgand ja Tanel Ruben, 19. juulil Tõnu Naissoo, Raul Vaigla ja Marko Naissoo kontserdiga "Tõnu Naissoo Eclectic Electric Trio", 26. juulil Holger Marjamaa kvartett (Holger Marjamaa, Mairo Marjamaa, Peedu Kass ja Dmitri Nikolajevski)

  5. Influência de diferentes meios de cultura sobre o crescimento de Pfaffia glomerata (Spreng. Pedersen (Amaranthaceae para conservação in vitro Influence of different culture media on the growth of Pfaffia glomerata (Spreng. Pendersen (Amaranthaceae for conservation in vitro

    Directory of Open Access Journals (Sweden)

    R.B.N. Alves

    2010-12-01

    Full Text Available Pfaffia glomerata ocorre em vários estados do Brasil e países limítrofes da região Sul às margens de rios e nas orlas das matas de galerias, é espécie hidrófita e heliófita. As raízes de espécies do gênero Pfaffia são usadas na medicina popular brasileira, especialmente como tônico, afrodisíaco e no controle do diabete. O objetivo deste trabalho foi estabelecer um banco de germoplasma in vitro de Pfaffia glomerata. O experimento em delineamento inteiramente casualizado foi conduzido com seis tratamentos: 1 MS + 2% de sacarose + 4% de sorbitol; 2 MS/2 + 2% de sacarose + 4% de sorbitol; 3 MS + 2% de sacarose + 4% de sorbitol + 2 mg L-1 de pantotenato de cálcio; 4 MS/2 + 2% de sacarose + 4% de sorbitol + 2 mg L-1de pantotenato de cálcio; 5 MS + 2% de sacarose + 3% de manitol + 2 mg L-1de pantotenato de cálcio; 6 MS/2 + 2% de sacarose + 3% de manitol + 2 mg L-1de pantotenato de cálcio. Os resultados obtidos foram submetidos à análise de variância e ao teste de separação de médias de Scott Knott. Os tratamentos um, três e quatro apresentaram, significativamente, o maior número de segmentos nodais por haste, quando comparados com os tratamentos dois, cinco e seis. O tratamento dois foi o mais indicado para a conservação in vitro da espécie por ter promovido menor crescimento das plantas (altura de 3,1±1,9 cm, alto índice de sobrevivência, 100% de explantes com brotação e o maior número de brotos por explante, após seis meses de cultivo. Todas as plântulas produziram raízes e não houve formação de calos, também não ocorreu hiperhidricidade nos tratamentos avaliados. As plantas aclimatizadas apresentaram 100% de sobrevivência no ambiente ex vitro. A manutenção de acessos de P. glomerata no banco de germoplasma in vitro é viável tanto do ponto de vista da conservação quanto economicamente.Pfaffia glomerata occurs in several states of Brazil and its neighboring countries in the south region at riverbanks and gallery forests. It is a hydrophyte and heliophyte species. The roots of the genus Pfaffia are used in Brazilian folk medicine especially as tonic, aphrodisiac and to control diabetes. The aim of this work was to establish an in vitro germplasm bank for Pfaffia glomerata. The experiment was carried out in completely randomized design with six treatments: 1 DM + 2% sucrose + 4% sorbitol; 2 DM/2 + 2% sucrose + 4% sorbitol; 3 DM + 2% sucrose + 4% sorbitol + 2 mg L-1 calcium pantothenate; 4 DM/2 + 2% sucrose + 4% sorbitol + 2 mg L-1 calcium pantothenate; 5 DM + 2% sucrose + 3% mannitol + 2 mg L-1 calcium pantothenate; 6 DM/2 + 2% sucrose + 3% mannitol + 2 mg L-1 calcium pantothenate. Results were subjected to analysis of variance and Scott Knott test for mean grouping. Treatments 1, 3 and 4 had a significantly larger number of nodal segments per stem, compared to Treatments 2, 5 and 6. Treatment 2 was the most appropriate for the in vitro conservation of this species since it led to the lowest growth (3.1±1.9 cm height, high survival rate, 100% explants with sprouting, and the largest number of sprouts per explant after six months of culture. All seedlings produced root and showed no formation of calluses or hyperhydricidity under the evaluated treatments. Acclimatized plants showed 100% survival in the ex vitro environment. Maintaining P. glomerata accessions in an in vitro germplasm bank is viable both economically and for conservation.

  6. How do European democracies compare when it comes to the length of ministerial careers?

    DEFF Research Database (Denmark)

    Bright, Jonathan; Doring, Holger; Little, Conor

    2015-01-01

    Ministerial careers can be notoriously nasty, brutish, and short, with the doctrine of ministerial accountability leading to numerous prematurely ended political careers. But how do European democracies compare? Looking at evidence from seven countries, Jonathan Bright, Holger Doring, and Conor...

  7. David Oistrahhi festival läheneb lõpule / Toivo Traks

    Index Scriptorium Estoniae

    Traks, Toivo

    2006-01-01

    Kontsertidest David Oistrahhi festivali raames: saksa viola da gamba mängija Holger Faust-Peters ja klavessinist Iren Lill 19. juulil Pärnu Eliisabeti kirikus, briti laulja Patricia Rozario ja RTE Vanbrugh Quartet 20. juulil Eliisabeti kirikus

  8. 21. I avati Tartu Kunstimuuseumis Eesti Kunstnikkude Ryhma näitus

    Index Scriptorium Estoniae

    2005-01-01

    Väljas on Jaan Vahtra, Friedrich Histi, Eduard Ole, Felix Randeli, Henrik Olvi, Juhan Raudsepa, Märt Laarmani, Arnold Akbergi, Edmond Arnold Blumenfeldti ja Aleksander Krimsi looming. Kuraatorid Reet Mark ja Holger Rajavee. Ilmub artiklite kogumik

  9. Mustvalge ja verine koomiksiklassik / Mart Kalvet

    Index Scriptorium Estoniae

    Kalvet, Mart, 1975-

    2010-01-01

    Arvustus: Miller, Frank. Sin City. [1. osa]., Karm hüvastijätt : [koomiks / tõlkija Holger Loodus ; Sin City logo: Steve Miller ; eestikeelse väljaande kujundus: Marko Russiver. Tallinn] : Eesti Päevaleht, [2009

  10. 2008 annual meeting on nuclear technology: topical sessions. Pt. 2. Construction of the final repository KONRAD

    International Nuclear Information System (INIS)

    Broeskamp, H.

    2008-01-01

    Summary report by Dipl.-Ing. Holger Broeskamp on the Topical Session ''Constructing the Final Repository KONRAD'' of the Annual Conference on Nuclear Technology held in Hamburg, May 27-29, 2008. (orig.)

  11. Omsættelige forureningstilladelser i USA

    DEFF Research Database (Denmark)

    Svendsen, Gert Tinggaard

    1992-01-01

    I en tidligere artikel i Samfundsøkonomen, har Hjorth-Andersen på overbevisende måde beskrevet de teoretiske fordele ved en eventuel inddragelse af "omsættelige forureningstilladelser" i miljøreguleringen. Spørgsmålet er, om de teoretiske forventninger kan indfries i praksis. Her kan erfaringerne...

  12. An Antropologist of Sound

    DEFF Research Database (Denmark)

    Groth, Sanne Krogh

    2015-01-01

    PROFESSOR PORTRAIT: Sanne Krogh Groth met Holger Schulze, newly appointed professor in Musicology at the Department for Arts and Cultural Studies, University of Copenhagen, to a talk about anthropology of sound, sound studies, musical canons and ideology.......PROFESSOR PORTRAIT: Sanne Krogh Groth met Holger Schulze, newly appointed professor in Musicology at the Department for Arts and Cultural Studies, University of Copenhagen, to a talk about anthropology of sound, sound studies, musical canons and ideology....

  13. Chemo Resistance of Breast Cancer Stem Cells

    Science.gov (United States)

    2007-05-01

    165-72. 60. Vestergaard J, Pedersen MW, Pedersen N, Ensinger C, Tumer Z, Tommerup N, et al. Hedgehog signaling in small-cell lung cancer : frequent......NUMBER Chemo Resistance of Breast Cancer Stem Cells 5b. GRANT NUMBER W81XWH-04-1-0471 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d

  14. Revolutsionäärid, kes ei pääsenud külma käest / Linda Kaljundi

    Index Scriptorium Estoniae

    Kaljundi, Linda, 1979-

    2006-01-01

    PÖFFil linastunud Põhjamaade filmidest: "Tüütu mees" ("Den Brysomme mannen", režissöör Jens Lien, Norra, 2006), "Seltsimees Pedersen" ("Gymnaslaerer Pedersen", režissöör Hans Petter Moland, Norra, 2006), "Kelle ridades seisad" ("Kenen joukoissa seisot", režissöör Jouko Aaltonen, Soome, 2006)

  15. We All Want to Live Longer and Nobody Wants to be Called Old. In: Oldetopia - an Exhibition on Age and Ageing

    DEFF Research Database (Denmark)

    Otto, Lene

    Kataloget bag udstillingen Oldetopia, vist på Medicinsk Museion fra den 12. oktober 2007 til den 14. december 2008. Bidrag af Camilla Mordhorst, Bente Vinge Pedersen, Thomas Söderqvist, Bente Klarlund Pedersen, Mette Sørensen, Tinna Stevnsner, Vilhelm A. Bohr, Bernard Jeune, Liv Carlé Mortensen, ...

  16. Perfume dermatitis in children sensitized to balsam of Peru in topical agents.

    Science.gov (United States)

    Fisher, A A

    1990-01-01

    Hjorth in his classic monogram "Eczematous Allergy to Balsams" emphasized that sensitization to balsam of Peru is most important since secondary allergens such as "fragrances" are ubiquitous. The application of a topical medication containing balsam of Peru to the skin of an infant, particularly in the occluded diaper area, seems a great way to sensitize the infant not only to balsam of Peru but also to our fragrant environment.

  17. Some statistics from the 2012 Lappet-faced Vulture chick ringing in ...

    African Journals Online (AJOL)

    Campbell Murn

    The long and the short of it: Some statistics from the 2012. Lappet-faced Vulture chick ringing in the Namib. Holger Kolberg1 and Peter Bridgeford2. Vultures Namibia, P.O. Box 3699, Walvis Bay, Namibia. 1 email: holgerk@mweb.com.na, 2 email: pmbridge@iway.na. Vultures Namibia once again ringed. Lappet-faced.

  18. Mõned mõtted "suvelugemisest" ja suvelugemisest / Peeter Helme

    Index Scriptorium Estoniae

    Helme, Peeter, 1978-

    2009-01-01

    Tutvustatakse ja soovitatakse raamatuid: Aleksejev, Tiit. Palveränd : lugu Esimesest ristisõjast. Tallinn : Varrak, 2008 ; Rebane, Kristi. Minu oma. Tallinn : Tänapäev, 2009 ; Kaints, Holger. Lennukivaatleja. Tallinn : Kultuurileht, 2009 ; Kehlmann, Daniel. Maailma mõõtmine. Tartu : Atlex, c2008 ; Zafón, Carlos Ruiz. Tuule vari. Tallinn : Varrak, 2008

  19. Evaluation of state-of-the-art hardware architectures for fast cone-beam CT reconstruction

    CERN Document Server

    Scherl, Holger

    2011-01-01

    Holger Scherl introduces the reader to the reconstruction problem in computed tomography and its major scientific challenges that range from computational efficiency to the fulfillment of Tuy's sufficiency condition. The assessed hardware architectures include multi- and many-core systems, cell broadband engine architecture, graphics processing units, and field programmable gate arrays.

  20. TiSSA pleenum "Sotsiaaltöö kriisi ajal" : mida on sotsiaaltööl pakkuda ja kes saab sellest kasu? / Regina Lind

    Index Scriptorium Estoniae

    Lind, Regina

    2010-01-01

    22.-27. aug. 2010 toimus Tallinna Ülikoolis TiSSA doktorantide eelkonverents ja pleenum. Pleenumil peetud sotsiaalteadlaste ettekannetest. Esinesid: Holger Ziegler, Karin Böllert, Catrin Heite, Hans van Ewijk, Walter Lorenz, Mikko Mäntysaari, Heinz Sünker, Synnöve Karvinen-Niinikoski, Olga Borodkina

  1. Kontsertide sari "Saue kontsertsügis" / Kristiina Liivik

    Index Scriptorium Estoniae

    Liivik, Kristiina

    2006-01-01

    Kontsertidel Sauel esinemas: vene laulja Aleksander Dedik kontserdiga "Minu südame laul" 7. sept., saksa tšellist Holger-Faust Peters 15. sept., järgnevatel kuudel Aleksandra Juozapenaite-Eesmaa, laulja Toomas Kuter ja ansambel Hinkus

  2. Endine Briti kaitseatašee Eestis : raiskajad tuleks vangi panna / Anna-Liisa Soomann

    Index Scriptorium Estoniae

    Soomann, Anna-Liisa

    2007-01-01

    Aastaid Eestis Suurbritannia kaitseatašeena töötanud ning hiljem kaitseministeeriumi nõustanud kolonelleitnant Glen Grant kritiseeris pärast Eestist lahkumist siinsete kaitsejõudude ülesehitust ning ametkondades levivat ressursside raiskamist. Lisa: Glen Grant. Vt. samas: Holger Roonemaa intervjuu Ants Laaneotsaga

  3. Pop / Koit Raudsepp

    Index Scriptorium Estoniae

    Raudsepp, Koit

    2003-01-01

    Heliplaatidest: Yeah Yeah Yeahs "Fever To Tell", Placebo "Sleeping With Ghosts", Sixpence None The Richer "Divine Discontent", Martin L.Gore "Counterfeit2" MJ Cole "Cut tothe Chase", Toktok Vs. Soffy O. "Toktok Vs Soffy O.", W.I.T. "Whatever It Takes", Holger Czukay & U-She "The New Millenium", The Fugees "Greatest Hits"

  4. A Survey of Plants with Anti-HIV Active Compounds and their Modes ...

    African Journals Online (AJOL)

    Administrator

    proteins, alkaloids, and biflavonoids inhibit various ... several plant families and species contain anti-HIV .... articles reviewed, only about a third were included .... membranes against free .... Pedersen, B.K. Low plasma level of adiponectin.

  5. Pilvelõhkujabuum Londonis / Maria-Kristiina Soomre

    Index Scriptorium Estoniae

    Soomre, Maria-Kristiina, 1978-

    2000-01-01

    Diskussiooni on põhjustanud uued tornid, mille on Londonisse kavandanud N. Foster, R. Rogers, N. Grimshaw, C. Wilkinson, R. Piano ja Ameerika büroo Kohn Pedersen Fox. Põhjusi, mis innustavad Londonist tornide linna tegema

  6. Kinobuss hakkas koolitama filmiõpetajaid

    Index Scriptorium Estoniae

    2006-01-01

    9. jaan. alustas Kinobuss õpetajatele mõeldud kursusega "Teaching with animation. Õpetamine animatsiooniga", mis on esimene neljast 2006.a. toimuvast koolitusest. Töötuba peavad Mikk Rand ja Hanne Pedersen Taanist

  7. Kinobuss hakkab õpetajaid koolitama

    Index Scriptorium Estoniae

    2006-01-01

    9. jaan. alustas Kinobuss õpetajatele mõeldud kursusega "Teaching with animation. Õpetamine animatsiooniga", mis on esimene neljast 2006.a. toimuvast koolitusest. Töötuba peavad Mikk Rand ja Hanne Pedersen Taanist

  8. Prescribing Practices and Cost of Drugs for Peptic Ulcer in a Primary ...

    African Journals Online (AJOL)

    infection, delayed diagnosis of gastric cancer and .... 100 mg and 200 mg intravenously, in Chinese patients with duodenal .... malabsorption of nutrients including iron, vitamin. B12 and .... Pedersen C, Hallas J . Use of proton pump inhibitors ...

  9. Appetit på mere

    DEFF Research Database (Denmark)

    Jensen, Niels Rosendal

    2014-01-01

    Anmeldelse af Steen Elsborg & Steen Høyrup Pedersens "Folkeoplysning og motivation for livslang læring..", hvor modeller for kortuddannedes ønske om mere uddannelse præsenteres på baggrund af empiriske arbejder...

  10. Generation and characterization of pigment mutants of ...

    African Journals Online (AJOL)

    acer

    2014-01-08

    Jan 8, 2014 ... aquatic ecosystems were studied. In the present ... logy and photosynthesis research (Stolbov, 1995;. Pedersen ... Microalgal strain and cultivation conditions ..... evaluated for their ecotoxicological effects using 124y-1 mutant.

  11. Comprehensive handbook of iodine: nutritional, biochemical, pathological and therapeutic aspects

    National Research Council Canada - National Science Library

    Preedy, Victor R; Burrow, Gerard N; Watson, Ronald R

    2009-01-01

    ... for Monitoring Effects of Iodine/Thyroid Status in Populations Inge Bülow Pedersen and Peter Laurberg 3 15 29 39 47 55 65 Section 2: General Aspects of Iodine Sources and Intakes in the Diet, Mai...

  12. Partial discharge transients: The field theoretical approach

    DEFF Research Database (Denmark)

    McAllister, Iain Wilson; Crichton, George C

    1998-01-01

    Up until the mid-1980s the theory of partial discharge transients was essentially static. This situation had arisen because of the fixation with the concept of void capacitance and the use of circuit theory to address what is in essence a field problem. Pedersen rejected this approach and instead...... began to apply field theory to the problem of partial discharge transients. In the present paper, the contributions of Pedersen using the field theoretical approach will be reviewed and discussed....

  13. Danmarkshistorie for hele verden

    DEFF Research Database (Denmark)

    Larsen, Steen Nepper

    2015-01-01

    Anmeldelse af "Building the Nation. N.F.S. Grundtvig and Danish National Identity". Edited by John A. Hall, Ove Korsgaard, and Ove K. Pedersen. Copenhagen: DJØF Publishing. 453 sider. 395 kr.......Anmeldelse af "Building the Nation. N.F.S. Grundtvig and Danish National Identity". Edited by John A. Hall, Ove Korsgaard, and Ove K. Pedersen. Copenhagen: DJØF Publishing. 453 sider. 395 kr....

  14. National culture and business model change: a framework for successful expansions

    DEFF Research Database (Denmark)

    Dalby, J.; Nielsen, L.S.; Lueg, Rainer

    2014-01-01

    Dalby, J., Nielsen, Lueg, R., L. S., Pedersen, L., Tomoni, A. C. 2014. National culture and business model change: a framework for successful expansions. Journal of Enterprising Culture, 22(4): 379-498.......Dalby, J., Nielsen, Lueg, R., L. S., Pedersen, L., Tomoni, A. C. 2014. National culture and business model change: a framework for successful expansions. Journal of Enterprising Culture, 22(4): 379-498....

  15. A Survey of the Almagest

    CERN Document Server

    Pedersen, Olaf

    2011-01-01

    "The Almagest", by the Greek astronomer and mathematician Ptolemy, is the most important surviving treatise on early mathematical astronomy, offering historians valuable insight into the astronomy and mathematics of the ancient world. Pedersen's 1974 publication, "A Survey of the Almagest", is the most recent in a long tradition of companions to the "Almagest'. Part paraphrase and part commentary, Pedersen's work has earned the universal praise of historians and serves as the definitive introductory text for students interested in studying the "Almagest". In

  16. Normal distribution of standing balance for healthy Danish children

    DEFF Research Database (Denmark)

    Pedersen, Line Kjeldgaard; Ghasemi, Habib; Rahbek, Ole

    2013-01-01

    Title: Normal distribution of standing balance for healthy Danish children – Reproducibility of parameters of balance. Authors Line Kjeldgaard Pedersen Habib Ghasemi Ole Rahbek Bjarne Møller-Madsen 1800 characters incl. spaces Background Pedobarographic measurements are increasingly used in child......Title: Normal distribution of standing balance for healthy Danish children – Reproducibility of parameters of balance. Authors Line Kjeldgaard Pedersen Habib Ghasemi Ole Rahbek Bjarne Møller-Madsen 1800 characters incl. spaces Background Pedobarographic measurements are increasingly used...

  17. Clinical epidemiology in the era of big data: new opportunities, familiar challenges

    OpenAIRE

    Ehrenstein,Vera; Nielsen,Henrik; Pedersen,Alma B; Johnsen,Søren P; Pedersen,Lars

    2017-01-01

    Vera Ehrenstein, Henrik Nielsen, Alma B Pedersen, Søren P Johnsen, Lars Pedersen Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus N, Denmark Abstract: Routinely recorded health data have evolved from mere by-products of health care delivery or billing into a powerful research tool for studying and improving patient care through clinical epidemiologic research. Big data in the context of epidemiologic research means large interlinkable data s...

  18. Processuel strategi i organisationer

    DEFF Research Database (Denmark)

    Gylling, Martin

    2014-01-01

    on process theory and strategy, which in these years aims to move focus away from the dominance of designed strategy. I.e. an approach to practice understood as methodological individualism and pragmatic rationality (Chia & Holt 2009; Steyaert 2007; Stacey 2011; Hjorth 2012). Through recent poststructuralist...... currents in the field of processual strategy thinking and organisational entrepreneurship, for example Chia & Holt’s creation philosophical research in strategy without design and Steyaert’s (2007) thinking on the concept of entrepreneuring; the process theoretical thinking of entrepreneurship...

  19. Artificial Photosynthesis: Beyond Mimicking Nature

    International Nuclear Information System (INIS)

    Dau, Holger; Fujita, Etsuko; Sun, Licheng

    2017-01-01

    In this Editorial, Guest Editors Holger Dau, Etsuko Fujita, and Licheng Sun introduce the Special Issue of ChemSusChem on “Artificial Photosynthesis for Sustainable Fuels”. Here, they discuss the need for non-fossil based fuels, introduce both biological and artificial photosynthesis, and outline various important concepts in artificial photosynthesis, including molecular and solid-state catalysts for water oxidation and hydrogen evolution, catalytic CO 2 reduction, and photoelectrochemical systems.

  20. Akvapopi tipud / Aleksander T. Yostafa

    Index Scriptorium Estoniae

    Yostafa, Aleksander T.

    2007-01-01

    Aleksander T. Yostafa reastab kümme parimat poplugu: The Beach Boys "Cool, Cool Water", Parliament Funcadelic "Aqua Boogie (A Psychoalphadiscobetabioaquadoloop)", Jane's Addiction "Ocean Size", U96 "Das Boot", Prince "Something In The Water (Does Not Compute)", Arthur Russell "Let's Go Swimming", Holger Czukay "Cool in the Pool", Vaiko Eplik & Eliit "Pihtas/põhjas", Duran Duran "Night Boat", Fela Kuti "Water Get No Enemy"

  1. Eesti proosa 1994 : [ka Noor-Eesti fenomenist 1994. a eesti proosas] / Toomas Liiv

    Index Scriptorium Estoniae

    Liiv, Toomas, 1946-2009

    1995-01-01

    Kangro, Bernard. Härjanädalate aegu; Kõiv, Madis Rännuaastad. Studia memoriae. I; Vanapa, Andres. Riiulid; Mutt, Mihkel. Rahvusvaheline mees; Berg, Maimu. Ma armastasin venelast. Nemad; Kross, Jaan. Järelehüüd; Kudu, Reet. Vabadus ja armastus; Mikelsaar, Henn. Käiski Nuustakul ära; Mihkelson, Ene. Nime vaev; Pukk, Holger. Suvest suveni; Trubetsky, Tõnu & Anti Pathique. Daam sinises; Traat, Mats. Kodu on ilus; Traat, Mats. Minge üles mägedele. Teine raamat, jt.

  2. Stability and selectivity of alkaline proteases in hydrophilic solvents

    DEFF Research Database (Denmark)

    Pedersen, Lars Haastrup; Ritthitham, Sinthuwat; Pleissner, Daniel

    2008-01-01

    , A. Bouchu, G. Descotes, Y. Queneau, Tetrahedron: Lett. 2000, 41, 3597. [7]           Q. Wu, N. Wang, Y.M. Xiao, D.S. Lu, X.F. Lin, Carbohydr. Res., 2004, 339, 2059. [8]           H.G. Park, H.N. Chang, Biotechnol. Lett. 2000, 22, 39 [9]           S. Riva, M. Nonini, G. Ottolina, B. Danieli......, Carbohydr. Res., 1998, 314, 259. [10]         N.R. Pedersen, R. Wimmer, R. Matthiesen, L.H. Pedersen, A. Gessesse, Tetrahedron: Asymmetry 2003, 14, 667. [11]         L. H. Pedersen, S. Ritthitham and M. Kristensen (2008) in Modern Biocatalysis Eds W. D. Fessner and T. Anthonsen, Wiley-VCH in press...

  3. Characterization of N-type glycosylation sites and glycan structures of Purple Acid Phosphatase Phytases from Wheat (Triticum aestivum L.)

    DEFF Research Database (Denmark)

    Dionisio, Giuseppe; Brinch-Pedersen, Henrik; Welinder, Karen Gjesing

    2011-01-01

    Wheat (Triticum aestivum L.) possesses preformed phytase activity in the grain that is essential to make phosphate available to cell metabolism and in food and feed (Brejnholt S. et al., 2011). Cereals contain the purple acid phosphatase type of phytases, PAPhy (Dionisio G. et al., 2011a). Mature......., Skov L. Brinch-Pedersen H. (2011). The degradation of phytate by microbial and wheat phytases is dependent on the phytate matrix and the phytase origin. J. Sci. Food Agri. (in press). Dionisio G., Madsen C.K., Holm P.B., Welinder K.G., Jørgensen M., Stoger E., Arcalis E., Brinch-Pedersen H. (2011a......) Cloning and Characterization of Purple Acid Phosphatase Phytases from Wheat (Triticum aestivum L.), Barley (Hordeum vulgare L.), Maize (Zea maize L.) and Rice (Oryza sativa L.). Plant Physiol. [in press, Jan 10, Epub ahead of print] Dionisio G., Brinch-Pedersen H., Welinder K.G., Jørgensen M. (2011b...

  4. Vandrefalken i Sydgrønland

    DEFF Research Database (Denmark)

    Falk, Knud; Møller, Søren

    2009-01-01

    Præsentation i forbindelse med overrækkelse af Bodil Pedersen Fondens Natur- og Miljøpris, Fuglenes hus, 11. juni 2009. Se http://www.dof.dk/index.php?id=nyheder&s=nyheder&m=visning&nyhed_id=638......Præsentation i forbindelse med overrækkelse af Bodil Pedersen Fondens Natur- og Miljøpris, Fuglenes hus, 11. juni 2009. Se http://www.dof.dk/index.php?id=nyheder&s=nyheder&m=visning&nyhed_id=638...

  5. The Effects of a Geomagnetic Storm on Thermospheric Circulation.

    Science.gov (United States)

    1987-01-01

    frequency. .*. p air density. olU 2 Pedersen and Hall conductivities. a P height intergrated Pedersen conductivity. horizontal viscous stress. * east...equations need to be ex- ,n~panded upon. The energy density is: (.2 1 + V2). I~i~iCPT +<V 2 . The horizontal viscous stress, including molecular and...with Z=0 at 80 km and Z=14.4 at 450 km for a total of 49 levels each 0.3 of a scale height apart. Also, the horizontal wind velocity, gas energy

  6. HOPE udveksling i Europa

    DEFF Research Database (Denmark)

    Pedersen, Ulla

    1996-01-01

    En artikel om deltagelse i HOPE (Hospital Professional Exchange) - 6 ugers studiebesøg på et hospital i udlandet. Ulla Pedersen fortæller om 6 uger med fokus på rehabilitering i det hollandske sundhedsvæsen.......En artikel om deltagelse i HOPE (Hospital Professional Exchange) - 6 ugers studiebesøg på et hospital i udlandet. Ulla Pedersen fortæller om 6 uger med fokus på rehabilitering i det hollandske sundhedsvæsen....

  7. Commentary on: "Comprehensive transcriptional analysis of early-stage urothelial carcinoma." Hedegaard J, Lamy P, Nordentoft I, Algaba F, Høyer S, Ulhøi BP, Vang S, Reinert T, Hermann GG, Mogensen K, Thomsen MB, Nielsen MM, Marquez M, Segersten U, Aine M, Höglund M, Birkenkamp-Demtröder K, Fristrup N, Borre M, Hartmann A, Stöhr R, Wach S, Keck B, Seitz AK, Nawroth R, Maurer T, Tulic C, Simic T, Junker K, Horstmann M, Harving N, Petersen AC, Calle ML, Steyerberg EW, Beukers W, van Kessel KE, Jensen JB, Pedersen JS, Malmström PU, Malats N, Real FX, Zwarthoff EC, Ørntoft TF, Dyrskjøt L. Cancer Cell. 2016 Jul 11;30(1):27-42.

    Science.gov (United States)

    Lee, Byron H

    2017-09-01

    Non-muscle-invasive bladder cancer (NMIBC) is a heterogeneous disease with widely different outcomes. We performed a comprehensive transcriptional analysis of 460 early-stage urothelial carcinomas and showed that NMIBC can be subgrouped into 3 major classes with basal- and luminal-like characteristics and different clinical outcomes. Large differences in biological processes such as the cell cycle, epithelial-mesenchymal transition, and differentiation were observed. Analysis of transcript variants revealed frequent mutations in genes encoding proteins involved in chromatin organization and cytoskeletal functions. Furthermore, mutations in well-known cancer driver genes (e.g., TP53 and ERBB2) were primarily found in high-risk tumors, together with APOBEC-related mutational signatures. The identification of subclasses in NMIBC may offer better prognostication and treatment selection based on subclass assignment. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. Värbamisfirma kuulutas jahi Eesti tippjuhtidele / Kurt Söderström ; interv. Andres Reimer

    Index Scriptorium Estoniae

    Söderström, Kurt

    2005-01-01

    Ida-Euroopa mõjuka tippjuhtide värbaja Pedersen&Partners Eesti juht Kurt Söderström selgitab milliste tippjuhtide värbamisest on firma Eestis huvitatud, milliseid väljavaateid ettevõte värvatavatele pakub ja kuidas juhikandidaadid leitakse

  9. The National Origins of Policy Ideas

    DEFF Research Database (Denmark)

    Campbell, John L.; Pedersen, Ove K.

    2014-01-01

    In this article John Campbell and Ove Pedersen argue that the way policy ideas are generated by knowledge regimes varies considerably across countries; and the effect on national politics is significant. The article is adapted from The National Origins of Policy Ideas: Knowledge Regimes...

  10. Derivative pricing with liquidity risk: Theory and evidence from the credit default swap market

    NARCIS (Netherlands)

    Bongaerts, D.; de Jong, F.; Driessen, J.

    2008-01-01

    We derive a theoretical asset-pricing model for derivative contracts that allows for expected liquidity and liquidity risk, and estimate this model for the market of credit default swaps (CDS). Our model extends the LCAPM of Acharya and Pedersen (2005) to a setting with derivative instruments and

  11. Simulation of erasure of photoinduced anisotropy by circularly polarized light

    DEFF Research Database (Denmark)

    Sajti, Sz.; Kerekes, Á.; Barabás, M.

    2001-01-01

    The temporal evolution of photoinduced birefringence is investigated on the basis of a model proposed by Pedersen and co-workers, This model is extended for the case of elliptically polarized light, and used to describe the erasure of photoinduced birefringence by circularly polarized light...

  12. Review of Literature on High Power Microwave Pulse Biological Effects

    Science.gov (United States)

    2009-08-01

    circulating fluid (Pedersen et al., 2004a,b). Earlier, in ultrasound hyperthermia, bone pain perceived by patients resulted in treatment termination in...15, 220-229. Ørstavik, K., Norheim, I., & Jørum, E. (2006). Pain and small-fiber neuropathy in patients with hypothyroidism . Neurology, 67, 786-791

  13. This is Not About Sex?

    DEFF Research Database (Denmark)

    Pedersen, Else Marie Wiberg

    2011-01-01

    This article engages the understanding of love and grace in Bernard's and Luther's theologies. Taking as a point of departure Anders Nygren's dichotomy of love in agape and eros, Wiberg Pedersen outlines some of the issues raised by Nygren's thesis. Arguing against Nygren's caricature of Bernard'...

  14. De-severing distance

    DEFF Research Database (Denmark)

    Jensen, Hanne Louise; de Neergaard, Maja

    2016-01-01

    De-severing Distance This paper draws on the growing body of mobility literature that shows how mobility can be viewed as meaningful everyday practices (Freudendal –Pedersen 2007, Cresswell 2006) this paper examines how Heidegger’s term de-severing can help us understand the everyday coping with ...

  15. Browse Title Index

    African Journals Online (AJOL)

    Items 1 - 50 of 519 ... Mohammed Ali, Teklehaimanot Asefaw, Hagos Beyene, Peter Byass, Mohammed Shishay, Mohammed Shishay Hasibu, Freddy Karup Pedersen. Vol 22 (2008): Special Edition: Bovine Tuberculosis in Ethiopia, A comparative study on the epidemiology and immuno-pathology of bovine tuberculosis in Bos ...

  16. Controversial EU deportation programme subjected to academic scrutiny

    DEFF Research Database (Denmark)

    Lemberg-Pedersen, Martin; McClelland, Ian

    2013-01-01

    On 3 May 2013, the Refugee Studies Centre hosted a workshop in Oxford, co-convened by Martin Lemberg-Pedersen (University of Copenhagen) and Dawn Chatty (RSC), to shed light on the little-publicised European Return Platform for Unaccompanied Minors (ERPUM)...

  17. Effect of hyperglycemia and hyperinsulinemia on the response of IL-6, TNF-alpha, and FFAs to low-dose endotoxemia in humans

    DEFF Research Database (Denmark)

    Krogh-Madsen, Rikke; Møller, Kirsten; Dela, Flemming

    2004-01-01

    Effect of hyperglycemia and hyperinsulinemia on the response of IL-6, TNF-alpha, and FFAs to low-dose endotoxemia in humans.Krogh-Madsen R, Moller K, Dela F, Kronborg G, Jauffred S, Pedersen BK. Professor of Internal Medicine, Dept. of Infectious Diseases 7641, Univ. Hospital Rigshospitalet...

  18. Processes of change in the organisation of gymnastics in Denmark - from community to commercialism

    DEFF Research Database (Denmark)

    Jensen, Andorra Lynn; Ottesen, Laila; Thing, Lone Friis

    on marketisation, consumerism, and being able to compete economically (Pedersen, 2011). Research question: How is Danish gymnastics developing in the sphere of state, market, and civil society, and what consequences does this have for the different forms of community? Methodically this question is examined...... consequences that affect the figuration especially in terms of the sense of community....

  19. Interrogative constructions in Danish Sign Language (DSL)

    DEFF Research Database (Denmark)

    Hansen, Julie

    This study investigates the primary types of interrogative constructions: Polar and content questions. The aim is to identify how and in which types of interrogative constructions the non-manual patterns described by Engberg-Pedersen (1993, 1998)are used. Furthermore, the aim is to identify...

  20. Sounding Relationships. Conference programme & Book of abstracts

    DEFF Research Database (Denmark)

    2009-01-01

    Content: Welcome to Aalborg.  Inge Nygaard Pedersen: Welcome from the chair of the organizing committee Tony Wigram Wlcome from the chair of the scientific committee Rita Cancino: Welcome from the head of faculty Hanne Mette Ridder: Welcome from the Danish Association of Music Therapists (MTL......) Sounding Relationships General Information Daily Program Social Program List of Participants Scientific Program Book of Abstracts...

  1. Synthesis and Characterization of New bis-Symmetrical Adipoyl ...

    African Journals Online (AJOL)

    NJD

    the methylene carbon chemical shift always ranged around two ... activated by using NaH as a strong base; also the small size of ... phase. We performed the extraction of neutral guest experiments only for D,L-alanine following Pedersen's procedure.27 The .... pared by the previously reported method32 as a white solid.

  2. 16 (No.2)

    African Journals Online (AJOL)

    mwakagugu

    of recruiting dental health personnel has an inherent weakness that may adversely ... aimed at training dental auxiliaries to upgrade their knowledge, attitudes and skills on ... undergo on-the-job training locally on how to assist .... Haukenes G, Shao JF, Mbena E, Rustad S. ... Pedersen B. Sexual behaviour does not reflect.

  3. Fusarium spp. Associated with Field-Grown Grain of Near-Isogenic Low Lignin and Wild-Type Sorghum

    Science.gov (United States)

    Fusarium spp. associated with field-grown grain of near-isogenic low lignin and wild-type sorghum. Deanna Funnell-Harris and Jeff Pedersen, USDA-ARS, Lincoln, NE Previous studies indicated that low lignin brown midrib (bmr) sorghum may be more resistant to Fusarium spp. than wild-type and that phen...

  4. Height-integrated conductivity in auroral substorms. 1. Data

    DEFF Research Database (Denmark)

    Gjerløv, Jesper Wittendorff; Hoffman, R.A.

    2000-01-01

    to select substorms which display a typical bulge-type auroral emission pattern and to organize the position of individual DE 2 passes with respect to key features in the emission pattern. The Hall and Pedersen conductances are calculated from electron precipitation data obtained by the low altitude plasma...

  5. Echo-Planar Imaging Based J-Resolved Spectroscopic Imaging for Improved Metabolite Detection in Prostate Cancer

    Science.gov (United States)

    2012-10-01

    Clinical Setting" was presented at the 20th International Society of Magnetic Resonance in Medicine (ISMRM) meeting in Melbourne , Australia (May 5-11...experience. Eur Urol 2001;40(1):75–83. 5. Chandra RV, Heinze S, Dowling R, Shadbolt C, Costello A, Pedersen J. Endorectal mag- netic resonance imaging

  6. Hykleri

    DEFF Research Database (Denmark)

    Lemberg-Pedersen, Martin

    2014-01-01

    In an analysis for Politiken, Dr. Martin Lemberg-Pedersen, Assistant Professor at AMIS, highlights how several NGO-reports have detailed practices of push backs of migrants, some of which are intercepted by masked commandos in the Aegean Sea, others who claim to have been beaten and pushed back...

  7. Desperate Housewives går amok på kvinderollen

    DEFF Research Database (Denmark)

    Pedersen, Vibeke

    2005-01-01

    Tv-serien Desperate Housewives tager verden med storm og vinder utallige priser med det gammelkendte tema: den uregerlige husmor. Men måske er den populære tv-serie også et opgør med postfeministernes forestillinger om kvinderollen? Medieforskeren Vibeke Pedersen ser serien i historisk sammenhæng...

  8. Letter to the editors

    African Journals Online (AJOL)

    ebutamanya

    6 juin 2016 ... Seyed Alireza Emamian, Michael Bachmann Nielsen, Jan Fog. Pedersen, Lars Ytte. Kidney Dimensions at Sonography: correlation with age, sex, and habitus in 665 adult volunteers. AJR. 1993; 160(1):83-86.PubMed | Google Scholar. 7. Justa Oyuela-Carrasco, Franciso Rodríguez-Castellanos, Eric.

  9. Modeling of TAN in recirculating aquaculture systems by AQUASIM

    DEFF Research Database (Denmark)

    Arvin, Erik; Pedersen, Lars-Flemming

    2011-01-01

    in Hirtshals, Denmark (Pedersen et al., 2009). Water from the fish rearing tank is treated in a sedimentation tank and subsequently by biological treatment in a submerged biofilter and in a trickling filter. Generally, the performance of the biological treatment was very well and average TAN concentrations...

  10. RJHS Vol 5(2) SOS.cdr

    African Journals Online (AJOL)

    ABEOLUGBENGAS

    Knez J. Endocrine-disrupting chemicals and male reproductive health. Reproductive. BioMedicine Online 2013; 26, 440– 448. 13. Christiansen S, Axelstad M, Boberg J, Vinggaard. AM, Pedersen GA, and Hass U. Low-dose effects of bisphenol A on early sexual development in male and female rats. Reproduction 2014; 147 ...

  11. On the History of the Continents

    DEFF Research Database (Denmark)

    Bo Pedersen, Flemming

    The present monograph is published to honour Dr. Tech. Flemming Bo Pedersen, Professor Emeritus in Hydrodynamics at the Technical University of Denmark, on his seventy year’s birthday and in gratitude for his continuous support to LICengineering A/S. The monograph collects Professor Emeritus, Dr...

  12. Rühmanäitus võib olla ka kunstnike mesallianss / Anne Lõugas

    Index Scriptorium Estoniae

    Lõugas, Anne, 1951-

    2002-01-01

    1.-23. III Kastellaanimajas avatud taani ja eesti graafikute ühisnäitusest "Hjorring - Tallinn". Evi Tihemets, Kelli Kagovere ja Urmas Viik eksponeerivad Taanis Hjorringis ning taanlased Maegens Larsen Stenderup, Per Borge Maltesen ja Lars Pedersen Tallinnas sügisel 2001 valminud töid. Pikemalt U. Viigi ofsettlitost "Vigala, 26. 07. 1939"

  13. Tripping up the perfect

    DEFF Research Database (Denmark)

    Pedersen, Peder Holm

    2009-01-01

    In mid-2008 the editor of Turbulens.net Peder Holm-Pedersen brought together film director and author Jørgen Leth and Sverre Raffnsøe, Professor of Philosophy at the Copenhagen Business School and head of the research program Management of Self- Management, to talk about rules, freedom...

  14. Genome Sequence of Leuconostoc mesenteroides subsp. cremoris Strain T26, Isolated from Mesophilic Undefined Cheese Starter.

    Science.gov (United States)

    Pedersen, T B; Kot, W P; Hansen, L H; Sørensen, S J; Broadbent, J R; Vogensen, F K; Ardö, Y

    2014-06-05

    Leuconostoc is the main group of heterofermentative bacteria found in mesophilic dairy starters. They grow in close symbiosis with the Lactococcus population and are able to degrade citrate. Here we present a draft genome sequence of Leuconostoc mesenteroides subsp. cremoris strain T26. Copyright © 2014 Pedersen et al.

  15. Diesel sisustab / Jenni Juurinen

    Index Scriptorium Estoniae

    Juurinen, Jenni

    2007-01-01

    Renzo Rosso poolt 1978. a. Itaalias asutatud rõivafirma Diesel sisustas 2007. a. kevadel Stay Inn-projekti raames katusekorteri Helsingi kesklinnas. Diesili kujundaja Vesa Kemppainen. Sisustuses on kasutatud peamiselt soome mööblit ja seintel eksponeeritud soome noorte kunstnike taieseid. Autoreid: Harri Koskinen (voodi), Thomas Pedersen (Stingrey kiiktool), Jenni Hiltunen (maalid)

  16. The Role of Trust as an Informal Institution in the Informal Sector in ...

    African Journals Online (AJOL)

    2014-11-21

    Nov 21, 2014 ... on the informal sector focused on the towns and cities of Africa. Later, the ... The methodology used for this analysis follows a small-N case study .... informal sector plays a significant role in economic development by providing .... a requirement for collaboration and networking in the sector (Pedersen 2001).

  17. Art and science

    DEFF Research Database (Denmark)

    Jørn Ankjær Pedersen: The Sun and the colours. Else Marie Bukdahl: The relation between art and science. Peter Wheeler: Screening of the film: The painter's eye. Jane Havshøj, Mogens Møllert, Nasser Moaedi Jorfi: The Moonlight Garden - a site specific project for Sharjah, De Forenede Arabiske...

  18. Using the lambda function to evaluate probe measurements of charged dielectric surfaces

    DEFF Research Database (Denmark)

    Rerup, T. O.; Crichton, George C; McAllister, Iain Wilson

    1996-01-01

    The use of Pedersen's λ function to evaluate electrostatic probe measurements of charged dielectric surfaces is demonstrated. With a knowledge of the probe λ function, the procedure by which this function is employed is developed, and thereafter applied to a set of experimental measurements avail...

  19. Variable type framing in Spanish constructions of directed motion

    DEFF Research Database (Denmark)

    Pedersen, Johan

    2014-01-01

    demonstrate in this article that this construction type tends to be acceptable whenever the lexical meaning of the verb implies an element of directed motion. Drawing on Goldberg (2006) and Pedersen (2009, 2013), I suggest that schematicity is a typological parameter, and, more specifically, that the term...... variable type framing may accommodate the case of variation under scrutiny here....

  20. Merrifield-simmons index and minimum number of independent sets in short trees

    DEFF Research Database (Denmark)

    Frendrup, Allan; Pedersen, Anders Sune; Sapozhenko, Alexander A.

    2013-01-01

    In Ars Comb. 84 (2007), 85-96, Pedersen and Vestergaard posed the problem of determining a lower bound for the number of independent sets in a tree of fixed order and diameter d. Asymptotically, we give here a complete solution for trees of diameter d...

  1. Organizing Entrepreneurship (research)

    DEFF Research Database (Denmark)

    Gartner, Bill

    2014-01-01

    The goal of this chapter is to offer some thoughts about the nature of the field of entrepreneurship, and particularly about the future of entrepreneurship scholarship. I begin with a recollection of a suggestion I made to students at doctoral seminars in the 1990s that 'all academic research...... on entrepreneurship could easily be read within a couple of months'. (I was recently reminded of this statement by Daniel Hjorth when I told him I was much behind in my journal reading.) Then, there simply wasn't much scholarship to digest. For example, it is well worth procuring one of the first handbooks...... on entrepreneurship, Sexton and Vesper's (1982) Encyclopedia of Entrepreneurship, to peruse the topics and to explore the depth of knowledge, then known, on the phenomenon of entrepreneurship. I was a doctoral student who was fortunate to attend the conference upon which the Encyclopedia was based, and it seemed...

  2. Vehicle Mode and Driving Activity Detection Based on Analyzing Sensor Data of Smartphones

    Directory of Open Access Journals (Sweden)

    Dang-Nhac Lu

    2018-03-01

    Full Text Available In this paper, we present a flexible combined system, namely the Vehicle mode-driving Activity Detection System (VADS, that is capable of detecting either the current vehicle mode or the current driving activity of travelers. Our proposed system is designed to be lightweight in computation and very fast in response to the changes of travelers’ vehicle modes or driving events. The vehicle mode detection module is responsible for recognizing both motorized vehicles, such as cars, buses, and motorbikes, and non-motorized ones, for instance, walking, and bikes. It relies only on accelerometer data in order to minimize the energy consumption of smartphones. By contrast, the driving activity detection module uses the data collected from the accelerometer, gyroscope, and magnetometer of a smartphone to detect various driving activities, i.e., stopping, going straight, turning left, and turning right. Furthermore, we propose a method to compute the optimized data window size and the optimized overlapping ratio for each vehicle mode and each driving event from the training datasets. The experimental results show that this strategy significantly increases the overall prediction accuracy. Additionally, numerous experiments are carried out to compare the impact of different feature sets (time domain features, frequency domain features, Hjorth features as well as the impact of various classification algorithms (Random Forest, Naïve Bayes, Decision tree J48, K Nearest Neighbor, Support Vector Machine contributing to the prediction accuracy. Our system achieves an average accuracy of 98.33% in detecting the vehicle modes and an average accuracy of 98.95% in recognizing the driving events of motorcyclists when using the Random Forest classifier and a feature set containing time domain features, frequency domain features, and Hjorth features. Moreover, on a public dataset of HTC company in New Taipei, Taiwan, our framework obtains the overall accuracy of 97

  3. Vehicle Mode and Driving Activity Detection Based on Analyzing Sensor Data of Smartphones.

    Science.gov (United States)

    Lu, Dang-Nhac; Nguyen, Duc-Nhan; Nguyen, Thi-Hau; Nguyen, Ha-Nam

    2018-03-29

    In this paper, we present a flexible combined system, namely the Vehicle mode-driving Activity Detection System (VADS), that is capable of detecting either the current vehicle mode or the current driving activity of travelers. Our proposed system is designed to be lightweight in computation and very fast in response to the changes of travelers' vehicle modes or driving events. The vehicle mode detection module is responsible for recognizing both motorized vehicles, such as cars, buses, and motorbikes, and non-motorized ones, for instance, walking, and bikes. It relies only on accelerometer data in order to minimize the energy consumption of smartphones. By contrast, the driving activity detection module uses the data collected from the accelerometer, gyroscope, and magnetometer of a smartphone to detect various driving activities, i.e., stopping, going straight, turning left, and turning right. Furthermore, we propose a method to compute the optimized data window size and the optimized overlapping ratio for each vehicle mode and each driving event from the training datasets. The experimental results show that this strategy significantly increases the overall prediction accuracy. Additionally, numerous experiments are carried out to compare the impact of different feature sets (time domain features, frequency domain features, Hjorth features) as well as the impact of various classification algorithms (Random Forest, Naïve Bayes, Decision tree J48, K Nearest Neighbor, Support Vector Machine) contributing to the prediction accuracy. Our system achieves an average accuracy of 98.33% in detecting the vehicle modes and an average accuracy of 98.95% in recognizing the driving events of motorcyclists when using the Random Forest classifier and a feature set containing time domain features, frequency domain features, and Hjorth features. Moreover, on a public dataset of HTC company in New Taipei, Taiwan, our framework obtains the overall accuracy of 97.33% that is

  4. Space Technology 5 (ST-5) Observations of the Imbalance of Region 1 and 2 Field-Aligned Currents

    Science.gov (United States)

    Le, Guan

    2010-01-01

    Space Technology 5 (ST-5) is a three micro-satellite constellation deployed into a 300 x 4500 km, dawn-dusk, sun-synchronous polar orbit from March 22 to June 21, 2006, for technology validations. In this study, we use the in-situ magnetic field observations from Space Technology 5 mission to quantify the imbalance of Region 1 (R1) and Region 2 (R2) currents. During the three-month duration of the ST5 mission, geomagnetic conditions range from quiet to moderately active. We find that the R1 current intensity is consistently stronger than the R2 current intensity both for the dawnside and the duskside large-scale field-aligned current system. The net currents flowing into (out of) the ionosphere in the dawnside (duskside) are in the order of 5% of the total RI currents. We also find that the net currents flowing into or out of the ionosphere are controlled by the solar wind-magnetosphere interaction in the same way as the field-aligned currents themselves are. Since the net currents due to the imbalance of the R1 and R2 currents require that their closure currents flow across the polar cap from dawn to dusk as Pedersen currents, our results indicate that the total amount of the cross-polar cap Pedersen currents is in the order of approx. 0.1 MA. This study, although with a very limited dataset, is one of the first attempts to quantify the cross-polar cap Pedersen currents. Given the importance of the Joule heating due to Pedersen currents to the high-latitude ionospheric electrodynamics, quantifying the cross-polar cap Pedersen currents and associated Joule heating is needed for developing models of the magnetosphere-ionosphere coupling.

  5. Comparison of ionospheric conductances and auroral luminosities observed simultaneously with the Chatanika radar and the DE 1 auroral imagers

    International Nuclear Information System (INIS)

    Robinson, R.M.; Vondrak, R.R.; Craven, J.D.; Frank, L.A.; Miller, K.

    1989-01-01

    Auroral luminosities at vacuum ultraviolet (VUV) wavelengths are combined with simultaneous and coincident ionospheric electron density measurements made by the Chatanika radar to relate ionospheric conductances to optical emissions. The auroral luminosities are obtained along the magnetic meridian through Chatanika with the auroral imaging photometers on the Dynamics Explorer 1 (DE 1) satellite as the radar scans in the magnetic meridian to measure electron density and conductivity as a function of altitude and latitude. The observations are used to determine an empirical relationship between the luminosities measured at VUV wavelengths and the Hall and Pedersen conductances. Of particular interest is the response of the photometer when using the VUV filter designated 123W. This filter admits the 130.4- and 135.6-nm emissions of atomic oxygen and the Lyman-Birge-Hopfield (LBH) bands of N 2 . Model calculations of the LBH and O I (135.6 nm) contributions to the total measured luminosity indicate that the relation between 123W luminosity and Pedersen conductance is less sensitive to the average energy of the precipitating electrons than the corresponding relation between the Hall conductance and 123W luminosity. This is because both the luminosity and Pedersen conductance decrease with increasing electron energy. The luminosity decreases with increasing energy because the emissions are more strongly absorbed by O 2 above the region of production. The Pedersen conductance decreases with increasing energy because the Pedersen mobility maximizes at an altitude of about 140 km. In contrast, the Hall conductance increases with increasing electron energy, so that the relation between Hall conductance and luminosity depends on the hardness of the precipitation

  6. Sound & The Senses

    DEFF Research Database (Denmark)

    Schulze, Holger

    2012-01-01

    How are those sounds you hear right now technically generated and post-produced, how are they aesthetically conceptualized and how culturally dependant are they really? How is your ability to hear intertwined with all the other senses and their cultural, biographical and technological constructio...... over time? And how is listening and sounding a deeply social activity – constructing our way of living together in cities as well as in apartment houses? A radio feature with Jonathan Sterne, AGF a.k.a Antye Greie, Jens Gerrit Papenburg & Holger Schulze....

  7. Air & Space Power Journal (ASPJ). Volume 27, Number 3, May-June 2013

    Science.gov (United States)

    2013-06-01

    to Hide Feature 27. M. Alex Johnson and Pete Williams, “ Cops : Weeks of Planning Went into Shootings at Colo. Batman Screening,” NBC News, 20 July...Gen. Andrews Says; Calls Anti-Submarine Measures ‘Successful,’ ” New York Times, 18 July 1942, 5. 46. Holger H. Herwig, “ Slaughter in Paradise...New York, February 1943, 7, 18–19, 25–26, 30–32. 48. Herwig, “ Slaughter in Paradise,” 5–7. 49. Ibid., 4. 50. Orlando J. Pérez, “Panama: Nationalism

  8. Air & Space Power Journal. Volume 27, Number 3

    Science.gov (United States)

    2013-06-01

    Nowhere to Hide Feature 27. M. Alex Johnson and Pete Williams, “ Cops : Weeks of Planning Went into Shootings at Colo. Batman Screening,” NBC News, 20 July...Gen. Andrews Says; Calls Anti-Submarine Measures ‘Successful,’ ” New York Times, 18 July 1942, 5. 46. Holger H. Herwig, “ Slaughter in Paradise...New York, February 1943, 7, 18–19, 25–26, 30–32. 48. Herwig, “ Slaughter in Paradise,” 5–7. 49. Ibid., 4. 50. Orlando J. Pérez, “Panama: Nationalism

  9. Jul på Kronborg

    DEFF Research Database (Denmark)

    Johnsen, Thøger

    Jul på Kronborg er historien, der lå bag tv-julekalenderen af samme navn. Den ligger både langt fra og tæt på tv-udgaven, som det oftest sker, når film og bog mødes. En stillelæsningsbog for voksne og halvvoksne, der gerne skal få smilet frem, give et enkelt gys og måske en lille tåre. Velkommen ...... til Holger Danskes og Hamlets univers – Velkommen til Kronborg....

  10. Generation of zonal flow in the Earth's dissipative ionospheric F-layer

    International Nuclear Information System (INIS)

    Kaladze, T.D.; Shad, M.; Tsamalashvili, L.V.

    2011-01-01

    Generation of zonal flow in the Earth's dissipative ionospheric F-layer is considered. Dissipation arises due to Pedersen conductivity acting as an inductive (magnetic) inhibition. It is shown that in contrast to previous investigations the zonal flow growth rate does not depend on small wave vector component of zonal flow mode, needs no instability condition and the spectral energy transferring (inverse cascade) process unconditionally takes place. -- Highlights: → Generation of zonal flow in the Earth's dissipative ionospheric F-layer is considered. → Dissipation arises due to Pedersen conductivity acting as inductive (magnetic) inhibition. → It is shown that such generation doesn't need any instability condition. → Energy transferring (inverse cascade) process takes place even for the small values of pumping intensity.

  11. European Values and Practices in Post-Communist Public Administration: The Baltic States

    DEFF Research Database (Denmark)

    Pedersen, Karin Hilmer; Johannsen, Lars

    2015-01-01

    In Chapter Twelve Karin Hilmer Pedersen and Lars Johannsen look into the changes in public administration and in the identity of public servants after the breakdown of the Soviet regime. Fundamental reconstructions of the political, economic and administrative systems of the Central and East...... democracy. Public administrations have undergone complete changes in their legal environment and deep structural reorganisation, combined with a high degree of turnover among staff. This has turned previous Soviet administrations into capable modern administrations. The question highlighted in this chapter...... is whether the public servants have also returned to Europe in the sense of sharing common European values and administrative identity. Pedersen and Johannsen find that the core principles of integrity and neutrality have been internalised and many, though not all, public servants see responsiveness...

  12. The influence of psychosocial variables on the use of religious/spiritual coping and quality of life among Danish cancer patients

    DEFF Research Database (Denmark)

    Pedersen, Heidi Frølund; Pedersen, Christina Gundgaard; Zachariae, Robert

    “THE INFLUENCE OF PSYCHOSOCIAL VARIABLES ON THE USE OF RELIGIOUS/SPIRITUAL COPING AND QUALITY OF LIFE AMONG DANISH CANCER PATIENTS” Pedersen, H.F., Pedersen, C.G., Zachariae, R. Psychooncology Research Unit, Aarhus University Hospital and University of Aarhus, Denmark Aim: Use of religious....../spiritual resources in coping may be prevalent in patients with cancer considering the life-threatening nature of the illness. Religious/spiritual coping has been found to have both positive and negative effects on quality of life and illness adjustment among cancer patients, with adaptive religious coping styles...... on quality of life Design/Method: A prospective study of 1.500 newly diagnosed Danish lung cancer patients, will be compared to a healthy, age and gender matched control group with respect to their use of religious/spiritual coping, quality of life, and relevant psychosocial variables. Lung cancer patients...

  13. Auroral ionospheric quiet summer time conductances

    International Nuclear Information System (INIS)

    Brekke, A.; Hall, C.

    1988-01-01

    The auroral zone E-region conductivities and conductances have been studied for 7 quiet time summer days. The Hall- and Pedersen conductances are found to follow the solar zenith variations in a rather regular fashion, and empirical formulas for these conductances are obtained. The choice of proper collision frequency models is found to be of great importance when deriving the conductances, and it is argued that some of the different results presented by other authors may be due to different models of the collision frequencies. The Hall- to Pedersen conductance ratios can only be used as an indicator of the energy of the precipitating auroral particles when the contribution from the background solar ionization is subtracted. When this is done this ratio takes much higher values than previously reported

  14. Incidence of diabetic macular edema and associated risk factors in a cohort of patients with type 1 diabetes in Denmark

    DEFF Research Database (Denmark)

    Rasmussen, Malin Lundberg

    Incidence of diabetic macular edema and associated risk factors in a cohort of patients with type 1 diabetes in Denmark. Rasmussen M.L.1, Pedersen R.B. 1, Sjølie A.K. 1, Grauslund J1 1University of Southern Denmark, Department of ophthalmology, Odense University Hospital, Denmark Purpose: To eval......Incidence of diabetic macular edema and associated risk factors in a cohort of patients with type 1 diabetes in Denmark. Rasmussen M.L.1, Pedersen R.B. 1, Sjølie A.K. 1, Grauslund J1 1University of Southern Denmark, Department of ophthalmology, Odense University Hospital, Denmark Purpose......: To evaluate the 16-year incidence of diabetic macular edema (DME) in a cohort of type 1 diabetic patients and to investigate possible risk factors of developing DME. Methods: This was a prospective cohort study of Danish type 1 diabetic patients. A total of 131 patients were examined at baseline in 1995...

  15. Social Stratification, Gender and Sport Participation

    OpenAIRE

    Aaron Reeves

    2012-01-01

    Correlations between social class and specific types of sport participation have frequently been observed (Crook 1997; Ceron-Anaya 2010; Dollman and Lewis 2010; Stalsberg and Pedersen 2010). However, discrete associations between occupational class positions and specific sporting activities overlook the complex interrelationships amongst these sports. Until recently, understanding the relationality of sport has been constrained by a lack of available and appropriate data. Work by Bourdieu (19...

  16. Targeting Neuropilin-1 in Prostate Cancer Bone Metastasis

    Science.gov (United States)

    2011-04-01

    USA; Dr. Leland W. K. Chung (Email: Leland.Chung@cshs.org), Uro -Oncology Research Program, Cedars-Sinai Medical Center, Los Angeles, CA, USA...Association for Cancer Research Annual Meeting, Los Angeles, CA, 2007. 25 Zhang S, Zhau HE, Iqbal S, Chung LWK, Wu D. Vascular endothelial growth...15. Pedersen LO , Hansen AS, Olsen AC, et al. The interaction between h2-microglobulin (h2m) and puri- fied class-I major histocompatibility (MHC

  17. Environmental Assessment of the Construction of the Joint Use Small Arms Range for the 934th Airlift Wing at Minneapolis-St. paul International Airport Air Reserve Station, Minnesota

    Science.gov (United States)

    2006-10-01

    environments can also mask verbal or mechanical warning signals such as sirens, bells, or horns. Range safety violations and unsafe operating conditions must...January 29, 1993), CEQ provides guidance to Federal agencies on how to “incorporate pollution prevention principles, techniques, and mechanisms into...take no formal action on the EA. If you have any questions or need further information, please contact Denise Pedersen Engen , principal reviewer for

  18. Infected bronchogenic cyst causing dysphagia and retrosternal pain

    DEFF Research Database (Denmark)

    Søndergaard, Eva Bjerre; Pedersen, Jesper Holst; Kleive, Dyre Berg

    2013-01-01

    Bronchogenic cysts are congenital. They are typically discovered in infancy or early childhood. Secondary infection of the cyst is uncommon. We present the case of a 17-year-old female who presented to the emergency department with intermediate onset of upper abdominal, and retrosternal chest pai......, Pedersen JH and Kleive D. Infected bronchogenic cyst causing dysphagia and retrosternal pain. Clin Respir J 2012; DOI:10.1111/j.1752-699X.2012.00296.x....

  19. Lee Pedersen’s work in theoretical and computational chemistry and biochemistry

    OpenAIRE

    Pedersen, Lee G

    2011-01-01

    Nature at the lab level in biology and chemistry can be described by the application of quantum mechanics. In many cases, a reasonable approximation to quantum mechanics is classical mechanics realized through Newton’s equations of motion. Dr. Pedersen began his career using quantum mechanics to describe the properties of small molecular complexes that could serve as models for biochemical systems. To describe large molecular systems required a drop-back to classical means and this led surpri...

  20. Numerical simulations on ion acoustic double layers

    International Nuclear Information System (INIS)

    Sato, T.; Okuda, H.

    1980-07-01

    A comprehensive numerical study of ion acoustic double layers has been performed for both periodic as well as for nonperiodic systems by means of one-dimensional particle simulations. For a nonperiodic system, an external battery and a resistance are used to model the magnetospheric convection potential and the ionospheric Pedersen resistance. It is found that the number of double layers and the associated potential buildup across the system increases with the system length

  1. Investigation of Triplet Exciplex Dynamics by Magnetic Field Effects due to the Triplet Mechanism

    OpenAIRE

    Ulrich, T.; Steiner, Ulrich; Föll, Rudolf E.

    1983-01-01

    A reaction scheme is described allowing for magnetic field effects on the chemical kinetics of triplet reactions due to the selective decay of triplet sublevels. The theoretical treatment of this scheme is outlined on the basis of a stochastic Liouville equation, taking into account the rotational diffusion of molecules in liquid solution. Whereas the exact solution of the general case is obtained by a numerical procedure as described by Pedersen and Freed, an approximate analytical expressio...

  2. Sound & The Society

    DEFF Research Database (Denmark)

    Schulze, Holger

    2014-01-01

    How are those sounds you hear right now socially constructed and evaluated, how are they architecturally conceptualized and how dependant on urban planning, industrial developments and political decisions are they really? How is your ability to hear intertwined with social interactions and their ...... and their professional design? And how is listening and sounding a deeply social activity – constructing our way of living together in cities as well as in apartment houses? A radio feature with Nina Backmann, Jochen Bonz, Stefan Krebs, Esther Schelander & Holger Schulze......How are those sounds you hear right now socially constructed and evaluated, how are they architecturally conceptualized and how dependant on urban planning, industrial developments and political decisions are they really? How is your ability to hear intertwined with social interactions...

  3. Responding to God

    DEFF Research Database (Denmark)

    Nielsen, Kirsten

    2009-01-01

    The theoretical background of the article consists of the theory of intertextuality and of Harald Bloom's theory of the strong precursors. As an example of this a modern Danish hymn by Holger Lissner, "Cain, where is your brother?" is analysed and it is shown how the poet is able to use two...... and images from the Danish nature are used in the hymns. It is further shown that modern poets are reluctant to talk about God as a God of history. As something new, Lars Busk Sørensen combines biblical imagery with philosophical concepts. It is concluded that biblical normativity is a challenge: "To live up...... to the biblical norm it must therefore be required of the theologian and the hymnwriter alike that their reading of the biblical message takes place not only as a repetition of the biblical words, but also as a reception and transformation of them."...

  4. Fluctuation mechanisms in superconductors nanowire single-photon counters, enabled by effective top-down manufacturing

    CERN Document Server

    Bartolf, Holger

    2016-01-01

    Holger Bartolf discusses state-of-the-art detection concepts based on superconducting nanotechnology as well as sophisticated analytical formulæ that model dissipative fluctuation-phenomena in superconducting nanowire single-photon detectors. Such knowledge is desirable for the development of advanced devices which are designed to possess an intrinsic robustness against vortex-fluctuations and it provides the perspective for honorable fundamental science in condensed matter physics. Especially the nanowire detector allows for ultra-low noise detection of signals with single-photon sensitivity and GHz repetition rates. Such devices have a huge potential for future technological impact and might enable unique applications (e.g. high rate interplanetary deep-space data links from Mars to Earth). Contents Superconducting Single-Photon Detectors Nanotechnological Manufacturing; Scale: 10 Nanometer Berezinskii-Kosterlitz Thouless (BKT) Transition, Edge-Barrier, Phase Slips Target Groups Researchers and students of...

  5. Rudolf Ahlswede’s lectures on information theory

    CERN Document Server

    Althöfer, Ingo; Deppe, Christian; Tamm, Ulrich

    Volume 1 : The volume “Storing and Transmitting Data” is based on Rudolf Ahlswede's introductory course on "Information Theory I" and presents an introduction to Shannon Theory. Readers, familiar or unfamiliar with the technical intricacies of Information Theory, will benefit considerably from working through the book; especially Chapter VI with its lively comments and uncensored insider views from the world of science and research offers informative and revealing insights. This is the first of several volumes that will serve as a collected research documentation of Rudolf Ahlswede’s lectures on information theory. Each volume includes comments from an invited well-known expert. Holger Boche contributed his insights in the supplement of the present volume. Classical information processing concerns the main tasks of gaining knowledge, storage, transmitting and hiding data. The first task is the prime goal of Statistics. For the two next, Shannon presented an impressive mathematical theory called Informat...

  6. Abdominal aortic aneurysms do not develop more aggressively among patients with a positive family history of the disease

    DEFF Research Database (Denmark)

    Mejnert Jørgensen, Trine; Wemmelund, Holger; Green, Anders

    Title: Abdominal aortic aneurysms no not develop more aggressively among patients with a positive family history of the disease Authors: Trine M. M. Joergensen, Holger Wemmelund, Anders Green, Jes Lindholt, Kim Houlind. Introduction: It is well known, that a family history of abdominal aortic...... aneurysm (AAA) strongly increases the risk of developing AAA, but it is still uncertain whether familial AAA’s develops differently than non-familial AAA’s. Objectives: To investigate whether familial AAA’s develop more aggressively than non-familial AAA’s by looking at growth rate, risk of surgery...... and rupture, as well as the size of the aneurysm at the time of diagnosis and the patient´s age at the time of operation, rupture and diagnosis. Design: Observational retrospective longitudinal study Materials: 318 patients (273 men and 45 women) with AAA diagnosed between 1996-2008 in Jutland, Denmark...

  7. Model-Based Analysis and Optimization of the Mapping of Cortical Sources in the Spontaneous Scalp EEG

    Directory of Open Access Journals (Sweden)

    Andrei V. Sazonov

    2007-01-01

    Full Text Available The mapping of brain sources into the scalp electroencephalogram (EEG depends on volume conduction properties of the head and on an electrode montage involving a reference. Mathematically, this source mapping (SM is fully determined by an observation function (OF matrix. This paper analyses the OF-matrix for a generation model for the desynchronized spontaneous EEG. The model involves a four-shell spherical volume conductor containing dipolar sources that are mutually uncorrelated so as to reflect the desynchronized EEG. The reference is optimized in order to minimize the impact in the SM of the sources located distant from the electrodes. The resulting reference is called the localized reference (LR. The OF-matrix is analyzed in terms of the relative power contribution of the sources and the cross-channel correlation coefficient for five existing references as well as for the LR. It is found that the Hjorth Laplacian reference is a fair approximation of the LR, and thus is close to optimum for practical intents and purposes. The other references have a significantly poorer performance. Furthermore, the OF-matrix is analyzed for limits to the spatial resolution for the EEG. These are estimated to be around 2 cm.

  8. Emotion Discrimination using spatially Compact Regions of Interest extracted from Imaging EEG Activity

    Directory of Open Access Journals (Sweden)

    Jorge Ivan Padilla-Buritica

    2016-07-01

    Full Text Available Lately, research on computational models of emotion had been getting much attention due to their potential for understanding the mechanisms of emotions and their promising broad range of applications that potentially bridge the gap between human and machine interactions. We propose a new method for emotion classification that relies on features extracted from those active brain areas that are most likely related to emotions. To this end, we carry out the selection of spatially compact regions of interest that are computed using the brain neural activity reconstructed from electroencephalography data. Throughout this study, we consider three representative feature extraction methods widely applied to emotion detection tasks, including Power spectral density, Wavelet, and Hjorth parameters. Further feature selection is carried out using principal component analysis. For validation purpose, these features are used to feed a support vector machine classifier that is trained under the leave-one-out cross-validation strategy. Obtained results on real affective data show that incorporation of the proposed training method in combination with the enhanced spatial resolution provided by the source estimation allows improving the performed accuracy of discrimination in most of the considered emotions, namely: dominance, valence, and linking.

  9. Analysis of EEG signals regularity in adults during video game play in 2D and 3D.

    Science.gov (United States)

    Khairuddin, Hamizah R; Malik, Aamir S; Mumtaz, Wajid; Kamel, Nidal; Xia, Likun

    2013-01-01

    Video games have long been part of the entertainment industry. Nonetheless, it is not well known how video games can affect us with the advancement of 3D technology. The purpose of this study is to investigate the EEG signals regularity when playing video games in 2D and 3D modes. A total of 29 healthy subjects (24 male, 5 female) with mean age of 21.79 (1.63) years participated. Subjects were asked to play a car racing video game in three different modes (2D, 3D passive and 3D active). In 3D passive mode, subjects needed to wear a passive polarized glasses (cinema type) while for 3D active, an active shutter glasses was used. Scalp EEG data was recorded during game play using 19-channel EEG machine and linked ear was used as reference. After data were pre-processed, the signal irregularity for all conditions was computed. Two parameters were used to measure signal complexity for time series data: i) Hjorth-Complexity and ii) Composite Permutation Entropy Index (CPEI). Based on these two parameters, our results showed that the complexity level increased from eyes closed to eyes open condition; and further increased in the case of 3D as compared to 2D game play.

  10. 17. Dialogue on waste management MV. Current developments in waste and resources economics. Proceedings; 17. DIALOG Abfallwirtschaft MV. Aktuelle Entwicklungen in der Abfall- und Ressourcenwirtschaft. Tagungsband

    Energy Technology Data Exchange (ETDEWEB)

    Nelles, Michael (ed.)

    2016-08-01

    This proceedings of 17th DIALOG Waste Management Mecklenburg-Western Pomerania contains 13 lectures. The topics were: Phosphorus recycling of wastewater and sewage sludge (Robert Ristow); Current waste legislation developments (Wolfgang Siederer); Further development of the recycling industry (Andreas Bruckschen); Resource-efficient recycling business - a challenge for municipalities (Holger Thaerichen); Brick Recycling (Anette Mueller); Who has the buck? competence and responsibility in collection, transportation and recycling of waste electrical equipment (Hans-Bernhard Rhein); Recovery of biogenic waste - Development, status and prospects (Martin Kranert); Experience in the bio-waste collection in the district of Western Pomerania-Ruegen (Torsten Ewert); Biowaste concept of OVVD GmbH (Stephan Schuett); Quo vadis BAWA Schwerinum? Biowaste treatment facility Schwerin - first operation experience (Andreas Lange); Future marketing opportunities for compost (Anke Boisch); Status and prospects of waste and substance flow management (Michael Nelles); Development of separate collection of biowaste quantities in Mecklenburg-Western Pomerania. [German] Dieser Tagungsband von der 17. DIALOG Abfallwirtschaft Mecklenburg-Vorpommern in Rostock enthaelt 13 Vortraege. Die Themen waren: Phosphor-Recycling aus Abwasser und Klaerschlamm (Robert Ristow); Aktuelle abfallrechtliche Entwicklungen (Wolfgang Siederer); Weiterentwicklung der Recyclingwirtschaft (Andreas Bruckschen); Ressourceneffiziente Wertstoffwirtschaft ? eine Herausforderung fuer die Kommunen (Holger Thaerichen); Ziegelrecycling (Anette Mueller et. al.); Wer hat den schwarzen Peter? Zustaendigkeiten und Verantwortlichkeiten bei Sammlung, Transport und Verwertung von Elektroaltgeraeten (Hans-Bernhard Rhein); Verwertung biogener Abfaelle - Entwicklung, Stand und Perspektiven (Martin Kranert); Erfahrungen bei der Bioabfallerfassung im Landkreis Vorpommern-Ruegen (Torsten Ewert); Bioabfallkonzept der OVVD GmbH (Stephan

  11. Findings from the experience with the punch technique for auditory osseointegrated implants: A retrospective single center comparative study.

    Science.gov (United States)

    Bonilla, Alfonso; Magri, Carlos; Juan, Eulalia

    To compare the punch technique and linear incision with soft tissue reduction for the placement of auditory osseointegrated implants (AOI) and analyze results of osseointegration obtained with the punch technique as measured with the Implant Stability Quotient (ISQ). Case review of 34 patients who received auditory osseointegrated implants between January 2010 and July 2015 and were divided into two groups according to the surgical technique: 18 with the punch technique (PT) and 16 with the linear incision technique (LI). Minimum follow-up was four months (mean: 24 months; range 4-64 months). Included in the analysis were patient profiles and records of the demographic data, surgical indications, surgical technique, implant placement, surgical time, intraoperative complications, as well as postsurgical complications (Holgers classification) and implant stability quotients (ISQ). Use of larger abutments was significantly greater in the PT group (PT, 10mm; LI, 6mm, p<0.001). The PT technique resulted in a shorter procedure than the LI (PT, 20min; LI, 45min, p<0.001). Holgers classification scores identified significantly fewer skin complications one week after surgery for the PT group; however, only small differences were seen between the two groups at the one- and three-month control visits. As shown for our cohort, the punch technique for surgical placement of AOI is faster and presents fewer immediate postoperative complications when compared to the linear incision technique. The clinical application of the ISQ is a useful, easy method to demonstrate the status of osseointegration and, thus, the stability of the device. Copyright © 2017 Elsevier España, S.L.U. and Sociedad Española de Otorrinolaringología y Cirugía de Cabeza y Cuello. All rights reserved.

  12. What is changing?

    DEFF Research Database (Denmark)

    Vaaben, Nana Katrine; Humle, Didde Maria

    In this paper we depart from narrative organizational studies pointing to the introduction of change or innovation as important times for evoking, negotiating and enacting different notions and (re)constructions of the past, present and future and of “who we are” and “what we do” as organizations......, professions, groups and individuals (e.g. Linde, 2001; Humphreys & Brown, 2002; Søderberg 2006; Pedersen & Johansen, 2012; Humle & Frandsen, 2016). Our case is the current processes of reforming the Danish Public Schools and we turn our attention towards micro level interactions and storytelling practices...

  13. Upheaval buckling of heated pipelines: a comparative study of three analytical methods; Flambagem vertical de dutos aquecidos: um estudo comparativo de tres metodos analiticos

    Energy Technology Data Exchange (ETDEWEB)

    Cunha, Divino J.S.; Benjamin, Adilson C. [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil). Centro de Pesquisas

    2005-07-01

    Three analytical methods frequently used for analyzing upheaval buckling are presented and compared in this work: the Hobbs' method which is applied to straight pipelines, the Pedersen-Jensen's method and the JIP-Shell's method, both applied to pipelines containing initial imperfections. The basic equations of the three methods are outlined and its differences are appointed. Also it is studied the sensitivity of the response of the last two methods to the cover of soil and to the amplitude of the initial imperfection. (author)

  14. The role of fluctuation-induced transport in a toroidal plasma with strong radial electric fields

    Science.gov (United States)

    Roth, J. R.; Krawczonek, W. M.; Powers, E. J.; Hong, J. Y.; Kim, Y. C.

    1981-01-01

    Previous work employing digitally implemented spectral analysis techniques is extended to demonstrate that radial fluctuation-induced transport is the dominant ion transport mechanism in an electric field dominated toroidal plasma. Such transport can be made to occur against a density gradient, and hence may have a very beneficial effect on confinement in toroidal plasmas of fusion interest. It is shown that Bohm or classical diffusion down a density gradient, the collisional Pedersen-current mechanism, and the collisionless electric field gradient mechanism described by Cole (1976) all played a minor role, if any, in the radial transport of this plasma.

  15. Perfluorooctane Sulfonate Concentrations in Amniotic Fluid, Biomarkers of Fetal Leydig Cell Function, and Cryptorchidism and Hypospadias in Danish Boys (1980-1996)

    DEFF Research Database (Denmark)

    Toft, Gunnar; Jönsson, Bo A; Bonde, Jens P

    2016-01-01

    BACKGROUND: Exposure to perfluorooctane sulfonate (PFOS) may potentially disturb fetal Leydig cell hormone production and male genital development. OBJECTIVES: We aimed to study the associations between levels of amniotic fluid PFOS, fetal steroid hormone, and insulin-like factor 3 (INSL3...... associations with fetal hormone levels may have long-term implications for reproductive health. CITATION: Toft G, Jönsson BA, Bonde JP, Nørgaard-Pedersen B, Hougaard DM, Cohen A, Lindh CH, Ivell R, Anand-Ivell R, Lindhard MS. 2016. Perfluorooctane sulfonate concentrations in amniotic fluid, biomarkers of fetal...

  16. Wie bewerten die Fluggäste den Klimaeinsatz und die Klimakommunikation von Fluggesellschaften? - eine empirische Studie der Haltungen deutscher und dänischer Flugreisenden

    DEFF Research Database (Denmark)

    Larsen, Aase Voldgaard

    . Wittmer (2010) hat die Haltung der Fluggäste der SWISS quantitativ untersucht und festgestellt, dass der Klimaeinsatz die Fluggäste anspricht und die Kommunikation darüber positiv auf das Image einwirkt. Diese Studie trägt jedoch den bei Larsen & Pedersen (2010) aufgedeckten Unterschieden nicht Rechnung......, sind: - Inwieweit unterscheiden sich die Passagierhaltungen bezüglich der Klimakommunikation und der erwarteten Klima-Einsatzgebiete? - Inwieweit beeinflusst die Klimakommunikation der Fluggesellschaften ihr Image und ihre Identität? Die auf bisherigen Untersuchungen gegründete Hypothese ist, dass die...

  17. Application of generalized inverse for analysis of magnetic anomalies due to a dyke model - Some numerical experiments

    Digital Repository Service at National Institute of Oceanography (India)

    Rao, M.M.M.; Murty, T.V.R.; SuryaPrakash, S.; Chandramouli, P.; Murthy, K.S.R.

    . Indust. Appl. Math, 11 (1963) 431-441. 10. Pedersen L B, Interpretation of potential field data – A generalised inverse approach, Geophy. Prosp. 25 (1977) 199-230. 11. Radhakrishna Murthy I V, Swamy K V & Jagannadha Rao S, Automatic inversion... generalised inverse technique in reconstruction of gravity anomalies due to a fault, Indian J. Pure. Appl. Math., 34 (2003) 31-47. 16. Ramana Murty T V, Somayajulu Y K & Murty C S, Reconstruction of sound speed profile through natural generalised inverse...

  18. In-process 3D geometry reconstruction of objects produced by direct light projection

    DEFF Research Database (Denmark)

    Andersen, Ulrik Vølcker; Pedersen, David Bue; Hansen, Hans Nørgaard

    2013-01-01

    al. 2011), this method has shown its potential with 3D printing (3DP) and selective laser sintering additive manufacturing processes, where it is possible to directly capture the geometrical features of each individual layer during a build job using a digital camera. When considering the process...... equipment such as coordinate measuring machines cannot be verified easily. This problem is addressed by developing an in-line reverse engineering and 3D reconstruction method that allows a true-to-scale reconstruction of a part being additively manufactured. In earlier works (Pedersen et al. 2010; Hansen et...

  19. Influence of Surge Motion on the Probability of Parametric Roll in a Stationary Sea State

    DEFF Research Database (Denmark)

    Jensen, Jørgen Juncher; Vidic-Perunovic, Jelena; Pedersen, Preben Terndrup

    2007-01-01

    A typical parametric roll scenario for a ship in head waves implies that the roll motion is coupled with vertical motion of the vessel. The added resistance of the ship is increased when the bow pitches down in a wave crest. As a consequence, the ship speed is slowed down and, hence, the roll...... resonance condition might be changed. In an attempt to study the influence of this speed variation in waves on parametric roll, the procedure for estimation of probability of parametric roll by Jensen and Pedersen (2006) has been extended to account for the surge motion of the vessel....

  20. A formalism for scattering of complex composite structures. II. Distributed reference points

    DEFF Research Database (Denmark)

    Svaneborg, Carsten; Pedersen, Jan Skov

    2012-01-01

    Recently we developed a formalism for the scattering from linear and acyclic branched structures build of mutually non-interacting sub-units.[C. Svaneborg and J. S. Pedersen, J. Chem. Phys. 136, 104105 (2012)] We assumed each sub-unit has reference points associated with it. These are well defined...... positions where sub-units can be linked together. In the present paper, we generalize the formalism to the case where each reference point can represent a distribution of potential link positions. We also present a generalized diagrammatic representation of the formalism. Scattering expressions required...

  1. Pre- and post-construction studies of conflicts between birds and wind turbines in coastal Norway (BirdWind). Report on findings 2007-2010

    OpenAIRE

    Bevanger, Kjetil Modolv; Berntsen, Finn Erik Harald; Clausen, Stig Morten; Dahl, Espen Lie; Flagstad, Øystein; Follestad, Arne; Halley, Duncan John; Hanssen, Frank Ole; Johnsen, Lars; Kvaløy, Pål; Lund-Hoel, Pernille*; May, Roelof Frans; Nygård, Torgeir; Pedersen, Hans-Christian; Reitan, Ole

    2011-01-01

    Bevanger, K., Berntsen, F., Clausen, S., Dahl, E.L., Flagstad, Ø. Follestad, A., Halley, D., Hanssen, F., Johnsen, L., Kvaløy, P., Lund-Hoel, P., May, R., Nygård, T., Pedersen, H.C., Reitan, O., Røskaft, E., Steinheim, Y., Stokke, B. & Vang, R. 2010. Pre- and post-construction studies of conflicts between birds and wind turbines in coastal Norway (BirdWind). Report on findings 2007-2010. – NINA Report 620. 152 pp. The BirdWind project (2007-2010) is now concluded. This report summarises th...

  2. Tony’s influence on the music therapy doctoral programme

    DEFF Research Database (Denmark)

    Ridder, Hanne Mette Ochsner

    2011-01-01

    The first important initiatives to establish international collaboration in music therapy research were taken in 1995 by Inge Nygaard Pedersen, Lars Ole Bonde and Tony Wigram. In 1997 Tony was given the task of leading, developing and creating a doctoral programme. The faculty of humanities granted...... the necessary resources, so that the first five PhD students could be enrolled. Under Tony’s leadership of the doctoral programme, the number of PhD students grew from the initial 5, to 10 in 2001 and 25 in 2010....

  3. Diabetes gestacional riesgo de desarrollar diabetes mellitus y factores de riesgo cardiovascular a medio plazo /

    OpenAIRE

    Albareda i Riera, Maria Mercè

    2002-01-01

    Descripció del recurs: 17 abril 2002 Títol obtingut de la portada digitalitzada A pesar de que el concepto de diabetes gestacional (DMG) como lo entendemos actualmente data de 1979, las primeras referencias que nos constan son del siglo XIX (Bennewitz 1824, Duncan 1882), y antes de 1979 ya se hab'an publicado estudios de cribaje, diagnóstico y mortalidad perinatal (Hoet 1954, Wilkerson 1957, O'Sullivan y Mahan 1964, Pedersen 1967, Mestman 1971). En la actualidad, la DMG se define como l...

  4. Clinical consequences of hospital variation in use of oral anticoagulant therapy after first-time admission for atrial fibrillation

    DEFF Research Database (Denmark)

    Hansen, M L; Gadsbøll, N; Rasmussen, S

    2009-01-01

    Abstract. Hansen ML, Gadsbøll N, Rasmussen S, Gislason GH, Folke F, Andersen SS, Schramm TK, Sørensen R, Fosbøl EL, Abildstrøm SZ, Madsen M, Poulsen HE, Køber L, Torp-Pedersen C (Gentofte University Hospital, Hellerup; Sygehus Nord, Køge; National Institute of Public Health; Rigshospitalet-Copenh...... thromboembolic events were observed amongst patients from low OAC use hospitals. Our study emphasizes the need for a continued vigilance on implementation of international AF management guidelines....

  5. Building Transdisciplinary Environmental Studies

    DEFF Research Database (Denmark)

    Holm, Jesper

    We will in this paper approach the challenge of building integrated environmental studies by presenting a crude frame of analysis which take into account both the physical aspects and the social-discursive articulations of environmental problems. This framework partly mirrors the approach of our...... department (Dept. of Environment, Technology and Social Studies, Roskilde University), and has originally in another version been presented in the book “Miljøregulering - tværvidenskabelige studier (Environmental Regulation. Interdisciplinary Studies)” (Holm, Kjærgård & Pedersen eds. 1997, in Danish) written...

  6. Bottomside sinusoidal irregularities in the equatorial F region. II - Cross-correlation and spectral analysis

    Science.gov (United States)

    Cragin, B. L.; Hanson, W. B.; Mcclure, J. P.; Valladares, C. E.

    1985-01-01

    Equatorial bottomside sinusoidal (BSS) irregularities have been studied by applying techniques of cross-correlation and spectral analysis to the Atmosphere Explorer data set. The phase of the cross-correlations of the plasma number density is discussed and the two drift velocity components observed using the retarding potential analyzer and ion drift meter on the satellite are discussed. Morphology is addressed, presenting the geographical distributions of the occurrence of BSS events for the equinoxes and solstices. Physical processes including the ion Larmor flux, interhemispheric plasma flows, and variations in the lower F region Pedersen conductivity are invoked to explain the findings.

  7. Test of the hypothesis; a lymphoma stem cells exist which is capable of self-renewal

    DEFF Research Database (Denmark)

    Kjeldsen, Malene Krag

      Test of the hypothesis; a lymphoma stem cell exist which is capable of self-renewal   Malene Krag Pedersen, Karen Dybkaer, Hans E. Johnsen   The Research Laboratory, Department of Haematology, Aalborg Hospital, Århus University   Failure of current therapeutics in the treatment of diffuse large B...... and sustaining cells(1-3). My project is based on studies of stem and early progenitor cells in lymphoid cell lines from patients with advanced DLBCL. The cell lines are world wide recognised and generously provided by Dr. Hans Messner and colleagues.   Hypothesis and aims: A lymphoma stem and progenitor cell...

  8. Key energy technologies for Europe

    DEFF Research Database (Denmark)

    Jørgensen, B.H.

    2005-01-01

    This report on key energy technologies is part of the work undertaken by the High-Level Expert Group to prepare a report on emerging science and technology trends and the implications for EU and Member State research policies. Senior Scientist BirteHolst Jørgensen, Risø National Laboratory...... contributed by Scientific Officer Edgar Thielmann, DG TREN, Head of Department Hans Larsen, RisøNational Laboratory, Senior Asset Manager Aksel Hauge Pedersen, DONG VE, Consultant Timon Wehnert, IZT-Berlin, and Senior Scientist Martine Uyterlinde, ECN...

  9. Superconductivity

    International Nuclear Information System (INIS)

    Andersen, N.H.; Mortensen, K.

    1988-12-01

    This report contains lecture notes of the basic lectures presented at the 1st Topsoee Summer School on Superconductivity held at Risoe National Laboratory, June 20-24, 1988. The following lecture notes are included: L.M. Falicov: 'Superconductivity: Phenomenology', A. Bohr and O. Ulfbeck: 'Quantal structure of superconductivity. Gauge angle', G. Aeppli: 'Muons, neutrons and superconductivity', N.F. Pedersen: 'The Josephson junction', C. Michel: 'Physicochemistry of high-T c superconductors', C. Laverick and J.K. Hulm: 'Manufacturing and application of superconducting wires', J. Clarke: 'SQUID concepts and systems'. (orig.) With 10 tabs., 128 figs., 219 refs

  10. Auroral vortex street formed by the magnetosphere–ionosphere coupling instability

    Directory of Open Access Journals (Sweden)

    Y. Hiraki

    2015-02-01

    Full Text Available By performing three-dimensional magnetohydrodynamic simulations including Alfvén eigenmode perturbations most unstable to the ionospheric feedback effects, we examined the auroral vortex street that often appears just before substorm onset. We found that an initially placed arc splits, intensifies, and rapidly deforms into a vortex street. We also found that there is a critical convection electric field for growth of the Alfvén eigenmodes. The vortex street is shown to be a consequence of coupling between the magnetospheric Alfvén waves carrying field-aligned currents and the ionospheric density waves driven by Pedersen/Hall currents.

  11. Auroral vortex street formed by the magnetosphere-ionosphere coupling instability

    Science.gov (United States)

    Hiraki, Y.

    2015-02-01

    By performing three-dimensional magnetohydrodynamic simulations including Alfvén eigenmode perturbations most unstable to the ionospheric feedback effects, we examined the auroral vortex street that often appears just before substorm onset. We found that an initially placed arc splits, intensifies, and rapidly deforms into a vortex street. We also found that there is a critical convection electric field for growth of the Alfvén eigenmodes. The vortex street is shown to be a consequence of coupling between the magnetospheric Alfvén waves carrying field-aligned currents and the ionospheric density waves driven by Pedersen/Hall currents.

  12. Effects of marine microbial biofilms on the biocide release rate from antifouling paints – A model-based analysis

    DEFF Research Database (Denmark)

    Yebra, Diego Meseguer; Kiil, Søren; Erik Weinell, Claus

    2006-01-01

    The antifouling (AF) paint model of Kiil et al. [S. Kiil, C.E. Weinell, M.S. Pedersen, K. Dam-Johansen, Analysis of self-polishing antifouling paints using rotary experiments and mathematical modelling, Ind. Eng. Chem. Res. 40 (2001) 3906-3920] and the simplified biofilm. growth model of Gujer...... and Warmer [W. Gujer, O. Warmer, Modeling mixed population biofilms, in: W.G. Characklis, K.C. Marshall (Eds.), Biofilms, Wiley-Interscience, New York, 1990] are used to provide a reaction engineering-based insight to the effects of marine microbial slimes on biocide leaching and, to a minor extent...

  13. Conditions for double layers in the earth's magnetosphere and perhaps in other astrophysical objects

    Science.gov (United States)

    Lyons, L. R.

    1987-01-01

    It is suggested that the features which govern the formation of the double layers are: (1) the divergence of the magnetospheric electric field, (2) the ionospheric conductivity, and (3) the current-voltage characteristics of auroral magnetic field lines. Also considered are conditions in other astrophysical objects that could lead to the formation of DLs in a manner analogous to what occurs in the earth's auroral zones. It is noted that two processes can drive divergent Pedersen currents within a collisional conducting layer: (1) sheared plasma flow applied anywhere along the magnetic field lines connected to the conducting layer and (2) a neutral flow with shear within the conducting layer.

  14. Browse Author Index

    African Journals Online (AJOL)

    A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All. O. Ozobialu, B.C. · Ozung, P.O.. P. Palm, Rudy · Paul, CW · Paul, E.D · Paul, ED · Pedersen, EM · Pessu, PO · Peter, EU · Peters, AO · Peters, E · PETERS, E. J · PETERS, E. J. · Peters, F.A. · Peters, OA · Pheulpin, P · PIERRE, K A · Polycarp, IM · Polycarp, IM · Popoola ...

  15. Mutual Solubility of MEG, Water and Reservoir Fluid: Experimental Measurements and Modeling using the CPA Equation of State

    DEFF Research Database (Denmark)

    Riaz, Muhammad; Kontogeorgis, Georgios; Stenby, Erling Halfdan

    2011-01-01

    This work presents new experimental phase equilibrium data of binary MEG-reservoir fluid and ternary MEG-water-reservoir fluid systems at temperatures 275-326 K and at atmospheric pressure. The reservoir fluid consists of a natural gas condensate from a Statoil operated gas field in the North Sea...... compounds. It has also been extended to reservoir fluids in presence of water and polar chemicals using a Pedersen like characterization method with modified correlations for critical temperature, pressure and acentric factor. In this work CPA is applied to the prediction of mutual solubility of reservoir...

  16. Virus de la Inmunodeficiencia Felina (VIF): soplan nuevos y buenos aires

    OpenAIRE

    Gómez, Nélida V.

    2008-01-01

    Este virus fue descubierto en 1986 y comunicado en 1987 por Pedersen y ha despertado un interés enorme en los investigadores, debido a que produce en el gato una enfermedad muy similar al SIDA del hombre. Es un retrovirus linfotrópico y constituye un preciado modelo experimental para el estudio de esta última enfermedad. Paralelamente a esto ha traído como consecuencia una profundización en el estudio de esta especie, especialmente su sistema inmune. Como todos los retrovi...

  17. Mitmest pilvelõhkujast piisab 9/11 mälestamiseks? / Eda Post

    Index Scriptorium Estoniae

    Post, Eda, 1983-

    2009-01-01

    New Yorgis terroristide hävitatud Maailma Kaubanduskeskuse kaksiktornide alale uue projekti leidmiseks korraldatud võistlusel valiti 2003. a. välja arhitekt Daniel Libeskindi kavand "Memory Foundation", mis nägi ette mälestuskompleksi hukkunutele tornide asukohas ja selle ümber viie uue pilvelõhkuja ehitamise. Tornid projekteerisid David Childs, Norman Foster, Richard Rogers, Fumihiko Maki ja arhitektuuribüroo Kohn Pedersen Fox. Valminud on torn Seitse, 2006. a. algas ehitus peaväljakul. Vaidlusest selle üle, kas on mõistlik viis torni välja ehitada

  18. Nrdp1-Mediated ErbB3 Increase during Androgen Ablation and its Contribution to Androgen-Independence

    Science.gov (United States)

    2013-04-01

    Matar P, Albanell J, Guzman M, Rojo F, Arribas J, et al.: ZD1839, a specifi c epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor...or AR cDNA whose protein product contains a Thr→ Ala muta- tion at the 877 residual position isolated from LNCaP cells (24). pCDNA-HER2 and pCDNA3...Scaltriti M, Verma C, Guzman M, Jimenez J, Parra JL, Pedersen K, Smith DJ, Landolfi S, Ramon y Cajal S, Arribas J, Baselga J. Lapatinib, a HER2 tyrosine

  19. Possible applications of crown-ethers to metal extraction using liquid membrane technology - a literature survey

    International Nuclear Information System (INIS)

    Dozol, M.

    1990-01-01

    Ether-crowns, discovered in 1967 by J.C. PEDERSEN, exhibit attractive complexive and extractive properties, enhanced in various fields, such as analytical chemistry, chemical synthesis, field of biology, or extractive chemistry. The investigations carried out on these macrocyclic compounds are continually increasing, as show in international literature. Among the focus of interest, the applications to metal extraction are extensively studied with crown compounds present in liquid phase or impregnated on supports (membranes or resins). The goal of this paper is to describe the application of crown-ethers to metal extraction, using liquid membrane processes. 69 refs

  20. Effects of Birkeland current limitation on high-latitude convection patterns

    International Nuclear Information System (INIS)

    Marklund, G.T.; Raadu, M.A.; Lindqvist, P.-A.

    1984-12-01

    It is shown how the high-latitude convection pattern may be mo- dified by substorm-enhanced polarization electric fields. These are generated whenever the flow of those Birkeland currents which are associated with ionospheric conductivity gradients is limited. Such Birkeland currents are fed mainly by the enhanced Pedersen current in the evening and morning sectors of the auro- ral oval and by the enhanced Hall current around local midnight. As the current limitation increases, the ionospheric potential, represented here by a symmetric two-cell pattern, will rotate clockwise and deform, just as the associated Birkeland current distribution. The resulting patterns are shown to agree well with observations. A pronounced westward intrusion of the equi- potential contours occurs in the auroral oval, and may be asso- ciated with the Westward Travelling Surge. This feature does not however require any assumed longitudinal conductivity gradi- ents. Rather it falls out naturally when the limitation of the enhanced Pedersen current is taken into account. (Author)

  1. Semantic similarity measure in biomedical domain leverage web search engine.

    Science.gov (United States)

    Chen, Chi-Huang; Hsieh, Sheau-Ling; Weng, Yung-Ching; Chang, Wen-Yung; Lai, Feipei

    2010-01-01

    Semantic similarity measure plays an essential role in Information Retrieval and Natural Language Processing. In this paper we propose a page-count-based semantic similarity measure and apply it in biomedical domains. Previous researches in semantic web related applications have deployed various semantic similarity measures. Despite the usefulness of the measurements in those applications, measuring semantic similarity between two terms remains a challenge task. The proposed method exploits page counts returned by the Web Search Engine. We define various similarity scores for two given terms P and Q, using the page counts for querying P, Q and P AND Q. Moreover, we propose a novel approach to compute semantic similarity using lexico-syntactic patterns with page counts. These different similarity scores are integrated adapting support vector machines, to leverage the robustness of semantic similarity measures. Experimental results on two datasets achieve correlation coefficients of 0.798 on the dataset provided by A. Hliaoutakis, 0.705 on the dataset provide by T. Pedersen with physician scores and 0.496 on the dataset provided by T. Pedersen et al. with expert scores.

  2. Auroral zone E-region conductivities during solar minimum derived from EISCAT data

    International Nuclear Information System (INIS)

    Schlegel, K.

    1988-01-01

    From two years of EISCAT data (1985-1986, a period of low solar activity) 8337 E-region conductivity profiles have been calculated as 5-min averages. From these profiles the height of the conductivity maxima for the Hall and Pedersen conductivities (H max ), the height-integrated Hall and Pedersen conductivities and the ratio of both have been computed. Histograms as well as average values of these quantities are displayed as a function of K p and of magnetic local time. The former results showed quantitatively the increase of the conductivities and the decrease of H max with increasing magnetic activity. The latter results revealed that on the average the conductivities are maximal in the early morning hours due to hard particle precipitation, H max being affected both by the solar zenith angle and by particle precipitation. The solar zenith angle dependence of the conductivities is only significant for low K p -values. Latitudinal profiles of the height-integrated conductivities show quantitatively the southward shift of the average conductivity maximum with increasing magnetic activity

  3. Linkage between the Danish National Health Service Prescription Database, the Danish Fetal Medicine Database, and other Danish registries as a tool for the study of drug safety in pregnancy

    Directory of Open Access Journals (Sweden)

    Pedersen LH

    2016-05-01

    Full Text Available Lars H Pedersen,1,2 Olav B Petersen,1,2 Mette Nørgaard,3 Charlotte Ekelund,4 Lars Pedersen,3 Ann Tabor,4 Henrik T Sørensen3 1Department of Clinical Medicine, Aarhus University, 2Department of Obstetrics and Gynecology, 3Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, 4Department of Fetal Medicine, Rigshospitalet, Copenhagen, Denmark Abstract: A linked population-based database is being created in Denmark for research on drug safety during pregnancy. It combines information from the Danish National Health Service Prescription Database (with information on all prescriptions reimbursed in Denmark since 2004, the Danish Fetal Medicine Database, the Danish National Registry of Patients, and the Medical Birth Registry. The new linked database will provide validated information on malformations diagnosed both prenatally and postnatally. The cohort from 2008 to 2014 will comprise 589,000 pregnancies with information on 424,000 pregnancies resulting in live-born children, ~420,000 pregnancies undergoing prenatal ultrasound scans, 65,000 miscarriages, and 92,000 terminations. It will be updated yearly with information on ~80,000 pregnancies. The cohort will enable identification of drug exposures associated with severe malformations, not only based on malformations diagnosed after birth but also including those having led to termination of pregnancy or miscarriage. Such combined data will provide a unique source of information for research on the safety of medications used during pregnancy. Keywords: malformations, teratology, therapeutic drug monitoring, epidemiological methods, registries

  4. On the Nocturnal Downward and Westward Equatorial Ionospheric Plasma Drifts During the 17 March 2015 Geomagnetic Storm

    Science.gov (United States)

    Bagiya, Mala S.; Vichare, Geeta; Sinha, A. K.; Sripathi, S.

    2018-02-01

    During quiet period, the nocturnal equatorial ionospheric plasma drifts eastward in the zonal direction and downward in the vertical direction. This quiet time drift pattern could be understood through dynamo processes in the nighttime equatorial ionosphere. The present case study reports the nocturnal simultaneous occurrence of the vertically downward and zonally westward plasma drifts over the Indian latitudes during the geomagnetic storm of 17 March 2015. After 17:00 UT ( 22:10 local time), the vertical plasma drift became downward and coincided with the westward zonal drift, a rarely observed feature of low latitude plasma drifts. The vertical drift turned upward after 18:00 UT, while the zonal drift became eastward. We mainly emphasize here the distinct bipolar type variations of vertical and zonal plasma drifts observed around 18:00 UT. We explain the vertical plasma drift in terms of the competing effects between the storm time prompt penetration and disturbance dynamo electric fields. Whereas, the westward drift is attributed to the storm time local electrodynamical changes mainly through the disturbance dynamo field in addition to the vertical Pedersen current arising from the spatial (longitudinal) gradient of the field aligned Pedersen conductivity.

  5. Uncertainties Involved in the Iopospheric Conductivity Estimation

    Directory of Open Access Journals (Sweden)

    Young-Sil Kwak

    2002-12-01

    Full Text Available Various uncertainties involved in ionospheric conductivity estimation utilizing the electron density profile obtained from the Sondrestrom incoherent scatter radar are examined. First, we compare the conductivity which is based on raw electron density and the one based on corrected electron density that takes into account the effects of the difference between the electron and ion temperatures and the Debye length. The corrected electron density yields higher Pedersen and Hall conductivities than the raw electron density does. Second, the dependence of collision frequency model on the conductivity estimation is examined. Below 110 km conductivity does not depend significantly on collision frequency models. Above 110 km, however, the collision models affect the conductivity estimation. Third, the influence of the electron and ion temperatures on the conductivity estimation is examined. Electron and ion temperatures carrying an error of about 10% do not seem to affect significantly the conductivity estimation. Fourth, also examined is the effect of the choice of the altitude range of integration in calculating the height-integrated conductivity, conductance. It has been demonstrated that the lower and upper boundaries of the integration are quite sensitive to the estimation of the Hall and Pedersen conductances, respectively.

  6. Macrocyclic ligands and their use in chemical separations

    International Nuclear Information System (INIS)

    Izatt, R.M.; Bradshaw, J.S.; Bruening, R.L.; Krakowiak, K.E.; Tarbet, B.J.

    1993-01-01

    Macrocyclic chemistry has had a phenomenal growth curve during the past three decades (Izatt et al.). Interest in this field was catalyzed by Pedersen's report of the synthesis and partial characterization of a large number of novel cyclic polyethers. The unusual affinity of these new compounds for and selectivity among alkali metal cations was noted (Pedersen) and quantitated (Izatt et al.). A 1987 National Academy of Science publication on separations listed three high priority needs in the separations field (King). These were to develop highly selective reagents capable of discriminating among similar chemical species, reagents capable of concentrating trace amounts of solutes even in the presence of large excesses of matrix solutes, and reagents capable of removing solutes from large quantities of solvent. Certain macrocycles offer the promise of being successful in achieving all three of these goals. This promise arises from their high selectivity for particular cations in various series of closely related cations, their large affinities for particular cations, and the ease with which they can be modified to meet particular needs inherent to chemical separations

  7. Undervisermetroen – www.undervisermetro.au.dk

    Directory of Open Access Journals (Sweden)

    Lene Tortzen Bager

    2012-09-01

    Full Text Available Undervisermetroen er et studiemiljøprojekt som udspringer af AU’s Studiemiljøundersøgelse 2011, og har pædagogisk kompetenceudvikling af og mere systematisk viden- og god praksisdeling mellem undervisere som formål. Metroen består af underviserbidrag og er konciperet af Lene Tortzen Bager, Gitte Wichmann-Hansen, CUDiM, og projektstyret, samlet og redigeret af Peter Stray Jørgensen, Lotte Rienecker og webredaktører Charlotte Albrechtsen og Anni Pedersen. Projektet er forlænget og udvikles nu videre i hele 2012. Selve metroen er en blivende resurse. ”Faculty Metro” is one of over 30 study environment projects at the Faculty of Arts, University of Aarhus, to come out of the study environment investigation, 2011. The purpose is development of teaching competencies and a forum for sharing good teaching and learning practices among faculty. The metro lines and stops contain multimodal good practice descriptions produced by faculty, edited by the Humanities department’s Center for Teaching Development and Digital Media. The idea is conceived by Lene Tortzen Bager and Gitte Wichmann-Hansen. Pedagogical and web crew in 2012 are Peter Stray Jørgensen, Lotte Rienecker, Charlotte Albrechtsen and Anni Pedersen. The metro is a permanent resource.

  8. Cross-B convection of artificially created, negative-ion clouds and plasma depressions: Low-speed flow

    International Nuclear Information System (INIS)

    Bernhardt, P.A.

    1988-01-01

    A negative-ion, positive-ion plasma produced by the release of an electron attachment chemical into the F region becomes electrically polarized by the collisions with neutrals moving across magnetic field lines. The resulting electric field causes E x B drift of the two ion species and the residual electrons. The cross-field flow of the modified ionosphere is computed using a two-dimensional numerical simulation which includes electron attachment and mutual neutralization chemistry, self-consistent electric fields, and three-species plasma transport. The velocity of the plasma is initially in the direction of the neutral wind because the negative-ion cloud is a Pedersen conductivity enhancement. As the positive and negative ions react, the Pedersen conductivity becomes depressed below the ambient value and the velocity of the plasma reverses direction. A plasma hole remains after the positive and negative ions have mutually neutralized. The E x B gradient drift instability produces irregularities on the upwind edge of the hole. These processes may be observed experimentally with optical and backscatter-radar diagnostics

  9. Assessment of ionospheric Joule heating by GUMICS-4 MHD simulation, AMIE, and satellite-based statistics: towards a synthesis

    Directory of Open Access Journals (Sweden)

    M. Palmroth

    2005-09-01

    Full Text Available We investigate the Northern Hemisphere Joule heating from several observational and computational sources with the purpose of calibrating a previously identified functional dependence between solar wind parameters and ionospheric total energy consumption computed from a global magnetohydrodynamic (MHD simulation (Grand Unified Magnetosphere Ionosphere Coupling Simulation, GUMICS-4. In this paper, the calibration focuses on determining the amount and temporal characteristics of Northern Hemisphere Joule heating. Joule heating during a substorm is estimated from global observations, including electric fields provided by Super Dual Auroral Network (SuperDARN and Pedersen conductances given by the ultraviolet (UV and X-ray imagers on board the Polar satellite. Furthermore, Joule heating is assessed from several activity index proxies, large statistical surveys, assimilative data methods (AMIE, and the global MHD simulation GUMICS-4. We show that the temporal and spatial variation of the Joule heating computed from the GUMICS-4 simulation is consistent with observational and statistical methods. However, the different observational methods do not give a consistent estimate for the magnitude of the global Joule heating. We suggest that multiplying the GUMICS-4 total Joule heating by a factor of 10 approximates the observed Joule heating reasonably well. The lesser amount of Joule heating in GUMICS-4 is essentially caused by weaker Region 2 currents and polar cap potentials. We also show by theoretical arguments that multiplying independent measurements of averaged electric fields and Pedersen conductances yields an overestimation of Joule heating.

    Keywords. Ionosphere (Auroral ionosphere; Modeling and forecasting; Electric fields and currents

  10. Clinical epidemiology in the era of big data: new opportunities, familiar challenges

    Directory of Open Access Journals (Sweden)

    Ehrenstein V

    2017-04-01

    Full Text Available Vera Ehrenstein, Henrik Nielsen, Alma B Pedersen, Søren P Johnsen, Lars Pedersen Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus N, Denmark Abstract: Routinely recorded health data have evolved from mere by-products of health care delivery or billing into a powerful research tool for studying and improving patient care through clinical epidemiologic research. Big data in the context of epidemiologic research means large interlinkable data sets within a single country or networks of multinational databases. Several Nordic, European, and other multinational collaborations are now well established. Advantages of big data for clinical epidemiology include improved precision of estimates, which is especially important for reassuring (“null” findings; ability to conduct meaningful analyses in subgroup of patients; and rapid detection of safety signals. Big data will also provide new possibilities for research by enabling access to linked information from biobanks, electronic medical records, patient-reported outcome measures, automatic and semiautomatic electronic monitoring devices, and social media. The sheer amount of data, however, does not eliminate and may even amplify systematic error. Therefore, methodologies addressing systematic error, clinical knowledge, and underlying hypotheses are more important than ever to ensure that the signal is discernable behind the noise. Keywords: electronic health records, healthcare administrative claims, medical record linkage, multicenter studies, validation studies

  11. Mini Smart Grid @ Copenhagen Business School

    DEFF Research Database (Denmark)

    Pedersen, Rasmus U.; Furtak, Simon J.; Häuser, Ivan

    2013-01-01

    Project Smart Grid: The Intelligent Electrical System Is the Way Forward In 2012 Peter Møllgaard from Department of Economics and Rasmus Pedersen from Department of IT Management initiated a new project supported by CBS Sustainability Platform. The purpose of the project is to establish an unders......Project Smart Grid: The Intelligent Electrical System Is the Way Forward In 2012 Peter Møllgaard from Department of Economics and Rasmus Pedersen from Department of IT Management initiated a new project supported by CBS Sustainability Platform. The purpose of the project is to establish...... an understanding of micro-economic and IT challenges related to Smart Grid technology. The mini-smart-grid project at Copenhagen Business School (MSC@CBS) project seeks to investigate the business opportunities and issues that arise from this new technology. The project revolves around the concepts of Smart Grids......, Smart Meters and prosumers. Smart Grids are a new method of managing electricity and power supply. It has not reached its full potential yet, but it offers a more interactive platform for both the consumer and the main supplier e.g. Dong Energy. The Smart Grid will collect and control the behavior...

  12. Viscosity Prediction for Petroleum Fluids Using Free Volume Theory and PC-SAFT

    Science.gov (United States)

    Khoshnamvand, Younes; Assareh, Mehdi

    2018-04-01

    In this study, free volume theory ( FVT) in combination with perturbed-chain statistical associating fluid theory is implemented for viscosity prediction of petroleum reservoir fluids containing ill-defined components such as cuts and plus fractions. FVT has three adjustable parameters for each component to calculate viscosity. These three parameters for petroleum cuts (especially plus fractions) are not available. In this work, these parameters are determined for different petroleum fractions. A model as a function of molecular weight and specific gravity is developed using 22 real reservoir fluid samples with API grades in the range of 22 to 45. Afterward, the proposed model accuracy in comparison with the accuracy of De la Porte et al. with reference to experimental data is presented. The presented model is used for six real samples in an evaluation step, and the results are compared with available experimental data and the method of De la Porte et al. Finally, the method of Lohrenz et al. and the method of Pedersen et al. as two common industrial methods for viscosity calculation are compared with the proposed approach. The absolute average deviation was 9.7 % for free volume theory method, 15.4 % for Lohrenz et al., and 22.16 for Pedersen et al.

  13. Stable isotopes in Lithuanian bioarcheological material

    Science.gov (United States)

    Skipityte, Raminta; Jankauskas, Rimantas; Remeikis, Vidmantas

    2015-04-01

    Investigation of bioarcheological material of ancient human populations allows us to understand the subsistence behavior associated with various adaptations to the environment. Feeding habits are essential to the survival and growth of ancient populations. Stable isotope analysis is accepted tool in paleodiet (Schutkowski et al, 1999) and paleoenvironmental (Zernitskaya et al, 2014) studies. However, stable isotopes can be useful not only in investigating human feeding habits but also in describing social and cultural structure of the past populations (Le Huray and Schutkowski, 2005). Only few stable isotope investigations have been performed before in Lithuanian region suggesting a quite uniform diet between males and females and protein intake from freshwater fish and animal protein. Previously, stable isotope analysis has only been used to study a Stone Age population however, more recently studies have been conducted on Iron Age and Late medieval samples (Jacobs et al, 2009). Anyway, there was a need for more precise examination. Stable isotope analysis were performed on human bone collagen and apatite samples in this study. Data represented various ages (from 5-7th cent. to 18th cent.). Stable carbon and nitrogen isotope analysis on medieval populations indicated that individuals in studied sites in Lithuania were almost exclusively consuming C3 plants, C3 fed terrestrial animals, and some freshwater resources. Current investigation demonstrated social differences between elites and country people and is promising in paleodietary and daily life reconstruction. Acknowledgement I thank prof. dr. G. Grupe, Director of the Anthropological and Palaeoanatomical State Collection in Munich for providing the opportunity to work in her laboratory. The part of this work was funded by DAAD. Antanaitis-Jacobs, Indre, et al. "Diet in early Lithuanian prehistory and the new stable isotope evidence." Archaeologia Baltica 12 (2009): 12-30. Le Huray, Jonathan D., and Holger

  14. Effects of energetic electrons on the electrodynamics in the ionosphere

    Directory of Open Access Journals (Sweden)

    A. Aksnes

    2004-01-01

    Full Text Available From the observations by the PIXIE and UVI cameras on board the Polar satellite, we derive global maps of the precipitating electron energy spectra from less than 1keV to 100keV. Based on the electron spectra, we generate instantaneous global maps of Hall and Pedersen conductances. The UVI camera provides good coverage of the lower electron energies contributing most to the Pedersen conductance, while PIXIE captures the high energy component of the precipitating electrons affecting the Hall conductance. By characterizing the energetic electrons from some tens of keV and up to about 100keV using PIXIE X-ray measurements, we will, in most cases, calculate a larger electron flux at higher energies than estimated from a simple extrapolation of derived electron spectra from UVI alone. Instantaneous global conductance maps derived with and without inclusion of PIXIE data have been implemented in the Assimilative Mapping of Ionospheric Electrodynamics (AMIE procedure, to study the effects of energetic electrons on electrodynamical parameters in the ionosphere. We find that the improved electron spectral characterization using PIXIE data most often results in a larger Hall conductance and a smaller inferred electric field. In some localized regions the increase in the Hall conductance can exceed 100%. On the contrary, the Pedersen conductance remains more or less unaffected by the inclusion of the PIXIE data. The calculated polar cap potential drop may decrease more than 10%, resulting in a reduction of the estimated Joule heating integrated over the Northern Hemisphere by up to 20%. Locally, Joule heating may decrease more than 50% in some regions. We also find that the calculated energy flux by precipitating electrons increases around 5% when including the PIXIE data. Combined with the reduction of Joule heating, this results in a decrease in the ratio between Joule heating and energy flux, sometimes exceeding 25%. An investigation of the relationship

  15. A three-dimensional, iterative mapping procedure for the implementation of an ionosphere-magnetosphere anisotropic Ohm's law boundary condition in global magnetohydrodynamic simulations

    Directory of Open Access Journals (Sweden)

    M. L. Goodman

    1995-08-01

    Full Text Available The mathematical formulation of an iterative procedure for the numerical implementation of an ionosphere-magnetosphere (IM anisotropic Ohm's law boundary condition is presented. The procedure may be used in global magnetohydrodynamic (MHD simulations of the magnetosphere. The basic form of the boundary condition is well known, but a well-defined, simple, explicit method for implementing it in an MHD code has not been presented previously. The boundary condition relates the ionospheric electric field to the magnetic field-aligned current density driven through the ionosphere by the magnetospheric convection electric field, which is orthogonal to the magnetic field B, and maps down into the ionosphere along equipotential magnetic field lines. The source of this electric field is the flow of the solar wind orthogonal to B. The electric field and current density in the ionosphere are connected through an anisotropic conductivity tensor which involves the Hall, Pedersen, and parallel conductivities. Only the height-integrated Hall and Pedersen conductivities (conductances appear in the final form of the boundary condition, and are assumed to be known functions of position on the spherical surface R=R1 representing the boundary between the ionosphere and magnetosphere. The implementation presented consists of an iterative mapping of the electrostatic potential ψ the gradient of which gives the electric field, and the field-aligned current density between the IM boundary at R=R1 and the inner boundary of an MHD code which is taken to be at R2>R1. Given the field-aligned current density on R=R2, as computed by the MHD simulation, it is mapped down to R=R1 where it is used to compute ψ by solving the equation that is the IM Ohm's law boundary condition. Then ψ is mapped out to R=R2, where it is used to update the electric field and the component of velocity perpendicular to B. The updated electric field and perpendicular velocity serve as new boundary

  16. Underground urbanity: from the carrefour à étages multiples to the ‘inner street’

    Directory of Open Access Journals (Sweden)

    Alvaro Clua

    2017-04-01

    Full Text Available As Manuel de Solà-Morales noted, urbanity relies on the variety and quality of relations between things, materials and human beings. Considered as such, how are we to achieve an underground urbanity? This paper seeks to address this question through a focussed reading of a number of European urban projects from the 20th century; all of which put special care into ensuring the quality of their subterranean passageways. We begin with the carrefour à giration, which was designed by Eugène Hénard in 1906, in order to identify four fundamental attributes of this kind of urbanity: legibility, spatiality, accessibility and activity. We then continue with a qualitative analysis of the 1933 Blå Bodarna passageway designed by Tage William-Olsson and Holger Blom in Slussen (Stockholm. Looking ahead some decades later, the sequence of passages under the Vienna Ring, built during the mayoralty of Franz J. Jonas, provides a good example of how fundamental the connectivity to the underground public transport system was to the success of these spaces. Finally, the article closes with a review of those underground places found in Santiago Calatrava’s Stadelhofen Station and the Stationsplein by Manuel de Solà-Morales: from the carrefour à étages multiples to the ‘inner street’.

  17. An intelligent utilization of the facettes of IT outsourcing - About costs and use of outsourcing in the branch of energy economy; Facetten des IT-Outsourcings intelligent nutzen - Ueber Kosten und Nutzen des Outsourcings in der Engergiewirtschaftsbranche

    Energy Technology Data Exchange (ETDEWEB)

    Koehler-Schute, Christiana (ed.)

    2008-07-01

    The restructuring of the German energy economy is connected with an enormous expenditure of know-how and substantial financial investments. Under this aspect, the book under consideration wants to suggest decision-makers in companies to include options to the outsourcing into their strategic considerations. Additionally, information for their decision preparation is to give to the decision-makers. The book contains the following contributions: (a) Information technology (IT) as business drivers in public utilities of the future (Holger Bonk, Wolfgang Herbers); (b) Smart outsourcing as creation of value factor (Ulrich Czubayko, Anke Schaefer); (c) From the web service to the full outsourcing in the energy market - an overview for decision making Make-or-Buy (Alexander-Ivo Franz); (d) Outsourcing in the energy industry from view of Siemens IT Solutions and services (Josef Kapp); (e) Consumption accounting, energy data management, customer data administration and data exchange from one hand: A standardised ASP solution offers data management from one hand (Mario Strauss, Kristina Seifert); (f) Smart of Metering systems, AMM and reading of the meter successfully outsourcen (Ralf Hoffmann, Simon Loeffler); (g) Contract design with the outsourcing with special consideration of the BPO and IT-outsourcing (Thomas Soebbing).

  18. Strategic Research of Patent Race Based on Patent Information%基于专利信息的企业专利竞赛战略研究

    Institute of Scientific and Technical Information of China (English)

    高山行; 王钦; 王迎

    2009-01-01

    借鉴Martin Moehrle的专利信息分析方法,结合Holger Ernst的专利组合分析,运用专利竞赛理论,选取日立、海尔、格力三家有代表性的企业,根据他们在空调技术方面的专利信息绘制分布图.通过图形勾勒出样本企业的技术分布,描绘企业之间的技术竞争轨迹,研究分析其专利竞赛行为和专利战略.通过技术类别和时间序列分析,判断竞争企业之间的相对位置和相对技术优势,指导R&D投资和专利战略选择.

  19. Two Different Percutaneous Bone-Anchored Hearing Aid Abutment Systems: Comparative Clinical Study.

    Science.gov (United States)

    Polat, Beldan; İşeri, Mete; Orhan, Kadir Serkan; Yılmazer, Ayça Başkadem; Enver, Necati; Ceylan, Didem; Kara, Ahmet; Güldiken, Yahya; Çomoğlu, Şenol

    2016-04-01

    To compare two different percutaneous bone-anchored hearing aid (BAHA) abutment systems regarding operation time, scar healing, quality of life, implant stability, audiologic results, and complications. The study involves a prospective multi-center clinical evaluation. Thirty-two consecutive patients who had undergone BAHA surgery from January 2011 to January 2013 in two tertiary centers were included in the study. The Glasgow Inventory Benefit Score was used to assess the patients at least 6 months after surgery. The operation time and complications were recorded. Implant stability quotient (ISQ) values were recorded using resonance frequency analysis. Holger's classification was used to evaluate skin reactions. The mean length of the operation was 39.2±4 min for standard abutment and 18.3±5.7 min for hydroxyapatite-coated abutment. ISQ scores were significantly better for standard abutment in all tests. The mean total Glasgow Inventory Benefit Score was 39.3±19 for the standard abutment and 46.3±24.5 for the hydroxyapatite-coated abutment groups, but there was no statistical significance between the two groups. There was no difference in audiological improvement between the two groups after surgery. Hydroxyapatite-coated abutment provided a shorter operation time that was significantly different from standard abutment. There were no significant differences between standard abutment and hydroxyapatite-coated abutment regarding audiologic improvement, quality of life, loading time, and complications.

  20. On improved understanding of plasma-chemical processes in complex low-temperature plasmas

    Science.gov (United States)

    Röpcke, Jürgen; Loffhagen, Detlef; von Wahl, Eric; Nave, Andy S. C.; Hamann, Stephan; van Helden, Jean-Piere H.; Lang, Norbert; Kersten, Holger

    2018-05-01

    Over the last years, chemical sensing using optical emission spectroscopy (OES) in the visible spectral range has been combined with methods of mid infrared laser absorption spectroscopy (MIR-LAS) in the molecular fingerprint region from 3 to 20 μm, which contains strong rotational-vibrational absorption bands of a large variety of gaseous species. This optical approach established powerful in situ diagnostic tools to study plasma-chemical processes of complex low-temperature plasmas. The methods of MIR-LAS enable to detect stable and transient molecular species in ground and excited states and to measure the concentrations and temperatures of reactive species in plasmas. Since kinetic processes are inherent to discharges ignited in molecular gases, high time resolution on sub-second timescales is frequently desired for fundamental studies as well as for process monitoring in applied research and industry. In addition to high sensitivity and good temporal resolution, the capacity for broad spectral coverage enabling multicomponent detection is further expanding the use of OES and MIR-LAS techniques. Based on selected examples, this paper reports on recent achievements in the understanding of complex low-temperature plasmas. Recently, a link with chemical modeling of the plasma has been provided, which is the ultimate objective for a better understanding of the chemical and reaction kinetic processes occurring in the plasma. Contribution to the Topical Issue "Fundamentals of Complex Plasmas", edited by Jürgen Meichsner, Michael Bonitz, Holger Fehske, Alexander Piel.

  1. Comment on: Measurement of the force exerted on the surface of an object immersed in a plasma. Eur. Phys. J. D 69: 91 (2015), DOI: 10.1140/epjd/e2015-50743-2

    Science.gov (United States)

    Czarnetzki, Uwe; Tsankov, Tsanko V.

    2015-10-01

    Surfaces exposed to a plasma experience a certain pressure that pushes them away from the volume. This effect has been investigated experimentally in a recent article by Thomas Trottenberg, Thomas Richter, and Holger Kersten from Kiel University/Germany [Eur. Phys. J. D 69, 91 (2015)]. The experimental results are impressive and have actually drawn the attention of the community to an interesting question which so far has been largely ignored. In addition to their experimental results the Kiel group proposes also a rough concept in order to explain their findings which provides certainly a basic qualitative understanding of the physical processes involved. However, on a closer inspection the picture developed so far is not entirely satisfying and the problem seems to require a more fundamental approach. This comment shows that the effect of the wall pressure can be described exactly using only analytical methods. The physical situation is analyzed by three different approaches. First, the simple case of only one spatial dimension is presented in detail. Second, the case of spherical symmetry is analyzed by some simplifying assumptions in order to investigate the effect of higher dimensionality. Third, a formal derivation for arbitrary geometry is given. This general result includes the one-dimensional case but does not allow a convenient connection between the pressures at the wall and in the center. Finally, the results are summarized and some conclusions are drawn.

  2. kayak Club

    CERN Multimedia

    Kayak club

    2014-01-01

    Quand les kayakistes insistent… Le Triat’Rhône est une compétition multisport d’équipe, avec trois disciplines qui  s’enchaînent : course à pied, kayak et VTT. Les athlètes du Canoë-Kayak du CERN, Joram Neupert épaulé par son Père Holger, participaient déjà l’année dernière à l’épreuve. Ils s’alignaient dans la catégorie famille parmi les 90 équipes au départ. Rudement freinés par une chute à vélo quand le podium leur souriait déjà, Joram laissait la victoire à son grand frère et son professeur de sport. Une année de préparation  à porté ses fruits car dimanche 29 juin 2014 sous un ciel de moins ...

  3. CERN scientists take part in the Tevatron Run II performance review committee

    CERN Multimedia

    Maximilien Brice

    2002-01-01

    Tevatron Run II is under way at Fermilab, exploring the high-energy frontier with upgraded detectors that will address some of the biggest questions in particle physics.Until CERN's LHC switches on, the Tevatron proton-antiproton collider is the world's only source of top quarks. It is the only place where we can search for supersymmetry, for the Higgs boson, and for signatures of additional dimensions of space-time. The US Department of Energy (DOE) recently convened a high-level international review committee to examine Fermilab experts' first-phase plans for the accelerator complex. Pictured here with a dipole magnet in CERN's LHC magnet test facility are the four CERN scientists who took part in the DOE's Tevatron review. Left to right: Francesco Ruggiero, Massimo Placidi, Flemming Pedersen, and Karlheinz Schindl. Further information: CERN Courier 43 (1)

  4. Associations between labial and whole salivary flow rates, systemic diseases and medications in a sample of older people

    DEFF Research Database (Denmark)

    Smidt, Dorte; Torpet, Lis Andersen; Nauntofte, Birgitte

    2010-01-01

    Smidt D, Torpet LA, Nauntofte B, Heegaard KM, Pedersen AML. Associations between labial and whole salivary flow rates, systemic diseases and medications in a sample of older people. Community Dent Oral Epidemiol 2010; 38: 422-435. © 2010 John Wiley & Sons A/S Abstract - Objective: To investigate...... the associations between age, gender, systemic diseases, medications and labial and whole salivary flow rates in older people. Methods: Unstimulated labial (LS) and unstimulated (UWS) and chewing-stimulated (SWS) whole salivary flow rates were measured in 389 randomly selected community-dwelling Danish women...... and 279 men aged 65-97 years. Systemic diseases, medications (coded according to the Anatomical Therapeutic Chemical (ATC) Classification System), tobacco and alcohol consumption were registered. Results: The number of diseases and medications was higher and UWS lower in the older age groups. On average...

  5. Multivariate analysis of elution parameters for RP-HPLC with charged aerosol detection of sucrose caprate regioisomers

    DEFF Research Database (Denmark)

    Lie, Aleksander; Pedersen, Lars Haastrup

    2012-01-01

    and Environmental Engineering, Aalborg University, Denmark Sugar fatty acid monoesters have been shown to possess antibiotic and insecticidal properties. The physical and chemical properties of sugar fatty acid esters depend on the saccharide moiety, fatty acid chain length, and both position and degree...... for sucrose caprate regioisomers. As a sensitive method based on mass detection, charged aerosol detection was used. The investigation was conducted using design-of-experiments (DOE) methodology for development and prediction of elution strategies. The elution profiles were described by a number of important......BIOCAT2012, Hamburg University of Technology Book of Abstracts, p290 ISBN 987-3-941492 L73) Multivariate analysis of elution parameters for RP-HPLC with charged aerosol detection of sucrose caprate regioisomers Aleksander Lie and Lars Haastrup Pedersen Department of Biotechnology, Chemistry...

  6. The National Origins of Policy Ideas

    DEFF Research Database (Denmark)

    Campbell, John L.; Pedersen, Ove K.

    In politics, ideas matter. They provide the foundation for economic policymaking, which in turn shapes what is possible in domestic and international politics. Yet until now, little attention has been paid to how these ideas are produced and disseminated, and how this process varies between...... countries. The National Origins of Policy Ideas provides the first comparative analysis of how "knowledge regimes" communities of policy research organizations like think tanks, political party foundations, ad hoc commissions, and state research offices, and the institutions that govern them generate ideas...... and communicate them to policymakers. John Campbell and Ove Pedersen examine how knowledge regimes are organized, operate, and have changed over the last thirty years in the United States, France, Germany, and Denmark. They show how there are persistent national differences in how policy ideas are produced. Some...

  7. Thermal equilibrium of pure electron plasmas across a central region of magnetic surfaces

    Science.gov (United States)

    Hahn, Michael; Pedersen, Thomas Sunn

    2009-06-01

    Measurements of the equilibria of plasmas created by emission from a biased filament located off the magnetic axis in the Columbia Non-neutral Torus (CNT) [T. S. Pedersen, J. P. Kremer, R. G. Lefrancois et al., Fusion Sci. Technol. 50, 372 (2006)] show that such plasmas have equilibrium properties consistent with the inner surfaces being in a state of cross-surface thermal equilibrium. Numerical solutions to the equilibrium equation were used to fit the experimental data and demonstrate consistency with cross-surface thermal equilibrium. Previous experiments in CNT showed that constant temperatures across magnetic surfaces are characteristic of CNT plasmas, implying thermal confinement times much less than particle confinement times. These results show that when emitting off axis there is a volume of inner surfaces where diffusion into that region is balanced by outward transport, producing a Boltzmann distribution of electrons. When combined with the low thermal energy confinement time this is a cross-surface thermal equilibrium.

  8. Thermal equilibrium of pure electron plasmas across a central region of magnetic surfaces

    International Nuclear Information System (INIS)

    Hahn, Michael; Pedersen, Thomas Sunn

    2009-01-01

    Measurements of the equilibria of plasmas created by emission from a biased filament located off the magnetic axis in the Columbia Non-neutral Torus (CNT) [T. S. Pedersen, J. P. Kremer, R. G. Lefrancois et al., Fusion Sci. Technol. 50, 372 (2006)] show that such plasmas have equilibrium properties consistent with the inner surfaces being in a state of cross-surface thermal equilibrium. Numerical solutions to the equilibrium equation were used to fit the experimental data and demonstrate consistency with cross-surface thermal equilibrium. Previous experiments in CNT showed that constant temperatures across magnetic surfaces are characteristic of CNT plasmas, implying thermal confinement times much less than particle confinement times. These results show that when emitting off axis there is a volume of inner surfaces where diffusion into that region is balanced by outward transport, producing a Boltzmann distribution of electrons. When combined with the low thermal energy confinement time this is a cross-surface thermal equilibrium.

  9. Spectrophotometry of peculiar B and A stars. XVIII - The helium rich variable stars HR 1890, Sigma Orionis E, and HD 37776

    Science.gov (United States)

    Adelman, S. J.; Pyper, D. M.

    1985-01-01

    Optical region spectrophotometry at 3300-7850 A has been obtained for three helium rich stars, HR 1890, Sigma Ori E, and HD 37776, of the Orion OB1 Association. New uvby-beta photometry of HR 1890 and HD 37776 as well as published data are also used to investigate the variability of these stars. A new period of 1.53862 days was determined for HD 37776. For all three stars H-beta varies in antiphase with strong He I lines. The spectrophotometric bandpass containing the strong He I line at 4471 A varies in phase with the R index of Pedersen and Thomsen (1977). Evidence is found for weak absorption features which appear to be an extension of the 5200 A feature seen in cooler CP stars.

  10. A DAFT DL_POLY distributed memory adaptation of the Smoothed Particle Mesh Ewald method

    Science.gov (United States)

    Bush, I. J.; Todorov, I. T.; Smith, W.

    2006-09-01

    The Smoothed Particle Mesh Ewald method [U. Essmann, L. Perera, M.L. Berkowtz, T. Darden, H. Lee, L.G. Pedersen, J. Chem. Phys. 103 (1995) 8577] for calculating long ranged forces in molecular simulation has been adapted for the parallel molecular dynamics code DL_POLY_3 [I.T. Todorov, W. Smith, Philos. Trans. Roy. Soc. London 362 (2004) 1835], making use of a novel 3D Fast Fourier Transform (DAFT) [I.J. Bush, The Daresbury Advanced Fourier transform, Daresbury Laboratory, 1999] that perfectly matches the Domain Decomposition (DD) parallelisation strategy [W. Smith, Comput. Phys. Comm. 62 (1991) 229; M.R.S. Pinches, D. Tildesley, W. Smith, Mol. Sim. 6 (1991) 51; D. Rapaport, Comput. Phys. Comm. 62 (1991) 217] of the DL_POLY_3 code. In this article we describe software adaptations undertaken to import this functionality and provide a review of its performance.

  11. Geologic isolation of nuclear waste at high latitudes: the role of ice sheets

    Science.gov (United States)

    Person, M.; McIntosh, J.; Iverson, N.; Neuzil, C.E.; Bense, V.

    2012-01-01

    Geologic isolation of high-level nuclear waste from the biosphere requires special consideration in countries at high latitudes (>40°N) owing to the possibility of future episodes of continental glaciation (Talbot 1999). It is now widely recognized that Pleistocene continental glaciations have had a profound effect on rates of sediment erosion (Cuffey & Paterson 2010) and deformation including tectonic thrusting (Pedersen 2005) as well as groundwater flow (Person et al. 2007; Lemieux et al. 2008a,b,c). In addition, glacial mechanical loads may have generated anomalous, or fossil, pore pressures within certain clay-rich confining units (e.g. Vinard et al. 2001). Because high-level nuclear wastes must be isolated from the biosphere as long as 1 million years (McMurry et al. 2003), the likelihood of one or more continental ice sheets overrunning high-latitude sites must be considered.

  12. Koguteos Rootsi põllumajanduse ajaloost / Ülle Tarkiainen

    Index Scriptorium Estoniae

    Tarkiainen, Ülle

    2004-01-01

    Rets. rmt.: Welinder, Stig, Pedersen, Ellen Anne. Jordbrukets första femtusen år 4000 f. Kr.-1000 e. Kr. Det svenska jordbrukets historia I. Borås, 1998 ; Myrdal, Janken. Jordbruket under feodalismen 1000-1700. Det svenska jordbrukets historia II. Borås, 1999 ; Gadd, Carl-Johan. Den agrara revolutionen 1700-1870. Det svenska jordbrukets historia III. Borås, 2000 ; Morell, Mats. Jordbruket i industrisamhället 1870-1945. Det svenska jordbrukets historia IV. Borås, 2001 ; Flygare, Irene A., Isacson, Maths. Jordbruket i välfärdssamhället 1945-2000. Det svenska jordbrukets historia V. Örebro, 2003

  13. Corotation-driven magnetosphere-ionosphere coupling currents in Saturn’s magnetosphere and their relation to the auroras

    Directory of Open Access Journals (Sweden)

    S. W. H. Cowley

    2003-08-01

    Full Text Available We calculate the latitude profile of the equatorward-directed ionospheric Pedersen currents that are driven in Saturn’s ionosphere by partial corotation of the magnetospheric plasma. The calculation incorporates the flattened figure of the planet, a model of Saturn’s magnetic field derived from spacecraft flyby data, and angular velocity models derived from Voyager plasma data. We also employ an effective height-integrated ionospheric Pedersen conductivity of 1 mho, suggested by a related analysis of Voyager magnetic field data. The Voyager plasma data suggest that on the largest spatial scales, the plasma angular velocity declines from near-rigid corotation with the planet in the inner magnetosphere, to values of about half of rigid corotation at the outer boundary of the region considered. The latter extends to ~ 15–20 Saturn radii (RS in the equatorial plane, mapping along magnetic field lines to ~ 15° co-latitude in the ionosphere. We find in this case that the ionospheric Pedersen current peaks near the poleward (outer boundary of this region, and falls toward zero over ~ 5°–10° equator-ward of the boundary as the plasma approaches rigid corotation. The peak current near the poleward boundary, integrated in azimuth, is ~ 6 MA. The field-aligned current required for continuity is directed out of the ionosphere into the magnetosphere essentially throughout the region, with the current density peaking at ~ 10 nA m-2 at ~ 20° co-latitude. We estimate that such current densities are well below the limit requiring field-aligned acceleration of magnetospheric electrons in Saturn’s environment ( ~ 70 nAm-2, so that no significant auroral features associated with this ring of upward current is anticipated. The observed ultraviolet auroras at Saturn are also found to occur significantly closer to the pole (at ~ 10°–15° co-latitude, and show considerable temporal and local time variability, contrary to expectations for corotation

  14. Androgens and Psychosocial Factors Related to Sexual Dysfunctions in Premenopausal Women

    DEFF Research Database (Denmark)

    Wåhlin-Jacobsen, Sarah; Kristensen, Ellids; Pedersen, Anette Tønnes

    2017-01-01

    a questionnaire on psychosocial factors and had blood sampled at days 6 to 10 in their menstrual cycle. Logistic regression models were built to test the association among hormone levels, psychosocial factors, and sexual end points. Main Outcome Measures Five different sexual end points were measured using...... duration longer than 2 years and mild depressive symptoms increased the risk of having all the sexual end points, including FSD in general and HSDD in particular in multivariate analyses. Conclusion In this large cross-sectional study, low sexual desire was significantly associated with levels of free...... testosterone and androstenedione, but FSD in general and HSDD in particular were not associated with androgen levels. Length of relationship and depression were associated with FSD including HSDD. Wåhlin-Jacobsen S, Kristensen E, Tønnes Pedersen A, et al. Androgens and Psychosocial Factors Related to Sexual Dysfunctions...

  15. Technical note 1. Review of the Geomicrobiological Aspects of SKB's Licence Application for a Spent Nuclear Fuel Repository in Forsmark, Sweden

    International Nuclear Information System (INIS)

    Parkes, R. John

    2011-10-01

    The report reviews whether the research work by SKB has been adequately comprehensive to describe the influence of microbial activity for sulphide production at repository depth. The report also documents any uncertainties with regard to predictions of rates and consequences of microbial sulphide production. SKB's assessment relies almost entirely on the results of the research that they commissioned from the Univ. of Goeteborg (Pedersen, 2010, Masurat et al., 2010a, b). This is not an unreasonable position, as there is no directly comparable research available. However, there is considerable literature demonstrating continued activity of sulphate-reducing bacteria over geological time scales and enhanced activity of sulphate-reducing bacteria in interaction with metals and corrosion, that should also be taken into consideration when assessing potential microbially influenced corrosion (Beech and Sunner, 2007) of the copper canister

  16. Urban sharing culture

    DEFF Research Database (Denmark)

    Fjalland, Emmy Laura Perez

    of the structures of the networked urban mobilities and holds the potentials to change the future mobilities. References Bauman, Zygmunt. 2000. Liquid Modernity. Cambridge: Polity. Beck, Ulrich. 1992. Risk Society: Towards a New Modernity (Published in Association with Theory, Culture & Society). London: SAGE......In urban areas sharing cultures, services and economies are rising. People share, rent and recycle their homes, cars, bikes, rides, tools, cloths, working space, knowhow and so on. The sharing culture can be understood as mobilities (Kesselring and Vogl 2013) of goods, values and ideas reshaping...... problems and side effects from concentration of consumption and contamination; and due to the shift from ownership to access it change our basic social cultural norms (Sayer 2005; Sayer 2011) about the ‘good’ life and social status (Freudendal-Pedersen 2007), commons and individuality, responsibility...

  17. Introduction to Analysis and Design of Plate Panels

    DEFF Research Database (Denmark)

    Jensen, Jørgen Juncher; Lützen, Marie

    , composite materials as glass-fibre-reinforced plates, sandwich plates and reinforced concrete plates are not included as they are topics for other courses. The present notes are mainly based on Pedersen and Jensen (1983), written in Danish. The first version of the notes was prepared by Marie L......The present notes cover plate theory dealing with bending, vibrations, elastic buckling and ultimate strength. The plate structures considered are isotropic, orthotropic and stiffened plates made of metallic materials. The main objective of the notes is to give an introduction to plates and plate...... panels and to present some fairly easy methods and results to be used in the design phase to judge, whether a plate panel can be considered safe from a structural point of view or requires a more detailed numerical analysis, typically using the Finite Element Method. Furthermore, a short introduction...

  18. Intelligent physical exercise at work: effect of supervision on motivation and reduction in neck-shoulder pain. Result from VIMS-study

    DEFF Research Database (Denmark)

    Gram, Bibi; Zebis, Mette Kreutzfeldt; Pedersen, Mogens Theisen

    INTELLIGENT PHYSICAL EXERCISE AT WORK: EFFECT OF SUPERVISION ON MOTIVATION AND REDUCTION IN NECK-SHOULDER PAIN? RESULT FROM VIMS-STUDY. Gram B1,Zebis MK1, Pedersen MT2, Andersen LL3, Sjøgaard G1 1: Inst. of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark 2....... Inst. of Exercise and Sport Sciences, University of Copenhagen, Denmark 3: National Research Centre for the Working Environment, Denmark Introduction It is well known that sedentary occupation with computer work is associated with development of pain in neck and shoulder. Studies have shown...... that physical exercise at work is effective in managing musculoskeletal pain (1,2). However, the effect of supervision during training sessions in workplace interventions needs to be clarified. Thus, the aim of this study was to evaluate the effect of different amount of supervision on training motivation...

  19. Autoimagen, mirada, y imaginarios de identidad

    DEFF Research Database (Denmark)

    Pedersen, Chistina Hee

    This paper sets off to discuss and analyse the workings of self image, gaze and imaginaries of identity in contexts of collaborative knowledge production. The discussion will be unfolded in relation to a performance done in the session and a text about a situation at a cultural event realised...... by GALF (Grupo de Autoconciencia de Lesbianas del Peru) in the mid 80és in Peru. The text in the centre of the paper was produced by a Danish feminist activist in a memory-work session realised in Peru in 2009 (Haug 1987, 1990, Davies 2000, 2007, Wiederberg 2011, 1998, Krøjer 2003, Hee Pedersen 2008......). It was written to explore a situation where social differences between women were meant not to be of little significance in relation to what happened in the situation described. ‘The text’ is here seen as an opportunity to take turns with and critically deconstruct naturalised processes of interpretation. I look...

  20. Thermolysis of (1R,2R)-1,2-dideuteriocyclobutane. An application of vibrational circular dichroism to kinetic analysis

    International Nuclear Information System (INIS)

    Chickos, J.S.; Annamalai, A.; Keiderling, T.A.

    1986-01-01

    The relative rates of geometric isomerization to racemization have been studied for the title compound by using a combination of infrared (IR) and vibrational circular dichroism (VCD) spectroscopies, respectively. The results are interpreted with a kinetic and mechanistic scheme which parallels that used by Berson, Pedersen, and Carpenter on a similar study of chiral cyclopropane-d 2 thermolysis. Relative rates of isomerization to stereomutation of 1.5 +/- 0.4 were obtained which can be interpreted to be consistent with a mechanism best described by random methylene rotation in tetramethylene-d 2 . This is the first application of VCD to kinetic analysis, and the advantages of IR techniques over the more usually employed UV spectroscopies to this type of basic mechanistic problem are illustrated

  1. Exploring the relationship between analgesic event rate and pain intensity in kidney stone surgery: A Repeated Time to Event Pilot Study

    DEFF Research Database (Denmark)

    Juul, Rasmus Vestergaard; Pedersen, Katja Venborg; Christrup, Lona Louring

    III-60 Rasmus Juul Exploring the relationship between analgesic event rate and pain intensity in kidney stone surgery: A Repeated Time to Event Pilot Study RV Juul(1), KV Pedersen(2, 4), LL Christrup(1), AE Olesen(1, 3), AM Drewes(3), PJS Osther(4), TM Lund(1) 1) Department of Drug Design...... a relationship with pain intensity has not yet been established. The aim of this pilot study was to discuss how best to investigate the relationship between RTTE hazard of analgesic events and pain intensity in postoperative pain. Methods: Data was available from 44 patients undergoing kidney stone surgery......). Gompertz and exponential distribution models were evaluated. Post-hoc linear mixed effect modelling was performed between estimated RTTE hazard and observed NRS using the lme4 package in R (3). Results: A Gompertz distribution model adequately described data, with a baseline event rate of 0.64h-1 (RSE 25...

  2. Learning, Leading and Letting go of Control

    DEFF Research Database (Denmark)

    Jensen, Annie Aarup; Kjær-Rasmussen, Lone Krogh; Iversen, Ann-Merete

    Learning, leading and letting go of control – Learner Led Approaches in Education Annie Aarup Jensen, Lone Krogh Kjær-Rasmussen, Ann-Merete Iversen and Anni Stavnskær Pedersen Abstract The aim of the paper is to introduce a new term in teaching in Higher Education: Learner Led Approaches...... in Education: LED. The sources of inspiration are many as are the experiences we draw from. Problem-based project work (PBL) being one, various classical teacher centered methods, and last but not least a variety of methods aiming towards developing creativity, innovational skills and entrepreneurship. LED...... is inspired by collaboration between professors from Aalborg University, Cornwall College and University College of Northern Denmark. Moravec (2008) claims that educational systems still operate in 1.0 or perhaps 2.0 mode while the surrounding cultures and societies operate in 3.0 mode. The amount...

  3. UniFlex - Collaborative on-line learning environment tool

    Directory of Open Access Journals (Sweden)

    Ole Borch

    2004-05-01

    Full Text Available

    Første gang publiceret i UNEV nr. 2: E-læringsplatforme - muligheder og potentialer, januar - marts 2004, red. Tom Nyvand og Michael Pedersen. ISSN 1603-5518.

    Increasing demands for remote on-line education are changing the way teaching and learning is performed. New behavior in using pedagogy and supporting technology is needed to drive the learning process. To facilitate the use of services for selected activities to participants in distance education, a web site named UniFlex (University Flexible learning has been developed and brought into use. The site is a comprehensive set of bookmarks including course taking, upload/download, and - of special significance - collaborative on-line project work. UniFlex has been developed to meet the requirement for a simple and cheap personalized interactive site, supporting problem oriented and project organized study form, which has characterized Aalborg University for more than 27 years.

  4. UniFlex - Collaborative on-line learning environment tool

    Directory of Open Access Journals (Sweden)

    Ole Borch

    2004-03-01

    Full Text Available Første gang publiceret i UNEV nr. 2: E-læringsplatforme - muligheder og potentialer, januar - marts 2004, red. Tom Nyvand og Michael Pedersen. ISSN 1603-5518. Increasing demands for remote on-line education are changing the way teaching and learning is performed. New behavior in using pedagogy and supporting technology is needed to drive the learning process. To facilitate the use of services for selected activities to participants in distance education, a web site named UniFlex (University Flexible learning has been developed and brought into use. The site is a comprehensive set of bookmarks including course taking, upload/download, and - of special significance - collaborative on-line project work. UniFlex has been developed to meet the requirement for a simple and cheap personalized interactive site, supporting problem oriented and project organized study form, which has characterized Aalborg University for more than 27 years.

  5. Multifocality as a prognostic factor in breast cancer patients registered in Danish Breast Cancer Cooperative Group (DBCG) 1996-2001

    DEFF Research Database (Denmark)

    Joergensen, L.E.; Gunnarsdottir, K.A.; Lanng, C.

    2008-01-01

    The purpose of this study was to investigate the prognostic influence of multifocality in breast cancer patients. In a cohort of 7196 patients there were 945 patients with multifocality. We found no prognostic influence of multifocality on overall survival when controlling for known prognostic......, Gunnarsdottir KA, Rasmussen BB, Moeller S, Lanng C. The prognostic influence of multifocality in breast cancer patients. Breast 2004;13:188-193]....... factors. We found a small but significant influence on disease-free survival (HR=1.16 [1.03-1.31]) and a strong correlation between multifocality and known prognostic factors. This was in accordance with an earlier study done on a smaller population and in a different period of time [Pedersen L...

  6. Photobook Week Aarhus 2017

    DEFF Research Database (Denmark)

    2017-01-01

    The discussions of the festival concentrated on distribution and markets. Using a regional axis, which mapped the Scandinavian practice in the global context, discussions were on themes related to publishing, distributing, buying, trading, and collecting photobooks. There was also a focus...... with UNSEEN Photobook Market in Amsterdam. The festival included a Dummy Doctoring Workshop, gallery talks, and the selection of shortlisted dummies from both the FotoBookFestival Kassel and the Nordic Dummy Award. Local and international booksellers offered the best from their shelves, and research based...... exhibitions were curated by Anne Elisabeth Toft (DK) and Claus Peder Pedersen (DK). As a special feature for Photobook Week Aarhus 2017, German collector and photo historian Thomas Wiegand curated an exhibition on the late German photographer Michael Schmidt’s photobooks, on shown at Aros Aarhus Art Museum....

  7. Can Household Benefit from Stochastic Programming Models?

    DEFF Research Database (Denmark)

    Rasmussen, Kourosh Marjani; Madsen, Claus A.; Poulsen, Rolf

    2014-01-01

    The Danish mortgage market is large and sophisticated. However, most Danish mortgage banks advise private home-owners based on simple, if sensible, rules of thumb. In recent years a number of papers (from Nielsen and Poulsen in J Econ Dyn Control 28:1267–1289, 2004 over Rasmussen and Zenios in J...... Risk 10:1–18, 2007 to Pedersen et al. in Ann Oper Res, 2013) have suggested a model-based, stochastic programming approach to mortgage choice. This paper gives an empirical comparison of performance over the period 2000–2010 of the rules of thumb to the model-based strategies. While the rules of thumb.......3–0.9 %-points (depending on the borrower’s level of conservatism) compared to the rules of thumb without increasing the risk. The answer to the question in the title is thus affirmative....

  8. Ultrastructural observations of lethal yellow (A/sup y//A/sup y/) mouse embryos

    Energy Technology Data Exchange (ETDEWEB)

    Calarco, P G; Pedersen, R A

    1976-01-01

    A/sup y//A/sup y/ embryos were identified by the presence of large excluded blastomeres (Pedersen, 1974) and examined cytologically and ultrastructurally. Cell organelles, inclusions and junctions in the excluded blastomeres were compared with those of non-excluded cells of A/sup y//A/sup y/ embryos and control embryos. Excluded blastomeres always had the fine structural characteristics of earlier developmental stages and may have arrested at the 4- to 8-cell stage or slightly later. Interior cells (inner cell mass) were observed in all mutant blastocysts. Nonexcluded cells of A/sup y//A/sup y/ embryos were normal until degenerative changes appear in the late blastocyst stage. The mode of action of the +/sup A/sup y/ gene was not determined, but evidence from this study and others indicates that the effects of +/sup A/sup y/ gene action occur over a wide range of time in early cleavage and implantation.

  9. Effect of specific resistance training on musculoskeletal pain symptoms

    DEFF Research Database (Denmark)

    Pedersen, Mogens Theisen; Andersen, Lars Louis; Jørgensen, Marie Birk

    2013-01-01

    .16, p = 0.045), and there was a significant dose-response relationship between training volume per session and change in pain index (ß = -0.20, p = 0.034). In contrast, training attendance (mean 1.69 sessions per week, SD = 0.8) was not significantly related to the change in pain index. In conclusion......, achieving higher accumulated training volumes was important for reducing musculoskeletal pain in female office workers. The training volume per session should be optimized by securing a load at 10-15 repetition maximum and adhering to principles of progressive overload.......ABSTRACT: Pedersen, MT, Andersen, LL, Jørgensen, MB, Søgaard, K, and Sjøgaard, G. Effect of specific resistance training on musculoskeletal pain symptoms: Dose-response relationship. J Strength Cond Res 27(1): 229-235, 2013-The purpose of this study was to investigate the dose-response of strength...

  10. Global and local Joule heating effects seen by DE 2

    Science.gov (United States)

    Heelis, R. A.; Coley, W. R.

    1988-01-01

    In the altitude region between 350 and 550 km, variations in the ion temperature principally reflect similar variations in the local frictional heating produced by a velocity difference between the ions and the neutrals. Here, the distribution of the ion temperature in this altitude region is shown, and its attributes in relation to previous work on local Joule heating rates are discussed. In addition to the ion temperature, instrumentation on the DE 2 satellite also provides a measure of the ion velocity vector representative of the total electric field. From this information, the local Joule heating rate is derived. From an estimate of the height-integrated Pedersen conductivity it is also possible to estimate the global (height-integrated) Joule heating rate. Here, the differences and relationships between these various parameters are described.

  11. UPWIND 1A2 Metrology. Final Report

    DEFF Research Database (Denmark)

    Eecen, P.J.; Wagenaar, J.W.; Stefanatos, N.

    . Since this problem covers many areas of wind energy, the work package is defined as a crosscutting activity. The objectives of the metrology work package are to develop metrology tools in wind energy to significantly enhance the quality of measurement and testing techniques. The first deliverable...... is a valuable tool for the further assessment and interest has been shown from other work packages, such as Training. This report describes the activities that have been carried out in the Work Package 1A2 Metrology of the UpWind project. Activities from Risø are described in a separate report: T.F. Pedersen...... was to perform a state of the art assessment to identify all relevant measurands. The required accuracies and required sampling frequencies have been identified from the perspective of the users of the data (the other work packages in UpWind). This work led to the definition of the Metrology Database, which...

  12. Mobility and language change in Denmark

    DEFF Research Database (Denmark)

    Monka, Malene

    featured substantial amounts of dialect features (Kristensen 1980; Pedersen 1986). In 2005 to 2010, researchers at the Danish National Research Center for Language Change in Real Time (LANCHART) and the University of Southern Denmark re-interviewed informants, thus providing data for investigating language......Mobility and language change in Denmark This paper demonstrates how mobility affects language change in real time and reports on the results of my PhD-thesis. In the thesis I made a real time panel study in three towns in distinct dialect areas in Denmark and examined language change in 23 speakers...... recorded in 1978 to 2010. The results emphasize the advantages of approaching mobility from different angles when investigating patterns of language change. The present paper focuses on six geographically and socially mobile informants. At the time of the early recordings, the three towns were in different...

  13.  Adiponectin in early and chronic rheumatoid arthritis and osteoarthritis

    DEFF Research Database (Denmark)

    Laurberg, Trine Bay

      Dato 31. januar 2006Title Adiponectin in early and chronic rheumatoid arthritis and osteoarthritisAuthors:Trine Bay Laurberg,Torkell Ellingsen,Jan Frystyk,Ib Hansen,Anette Jørgensen,Ulrik Tarp,Merete Lund Hetland,Kim Hørslev-Petersen,Nete Hornung,Jørgen Hjelm Poulsen,Allan Flyvbjerg,Kristian St......  Dato 31. januar 2006Title Adiponectin in early and chronic rheumatoid arthritis and osteoarthritisAuthors:Trine Bay Laurberg,Torkell Ellingsen,Jan Frystyk,Ib Hansen,Anette Jørgensen,Ulrik Tarp,Merete Lund Hetland,Kim Hørslev-Petersen,Nete Hornung,Jørgen Hjelm Poulsen,Allan Flyvbjerg......,Kristian Stengaard-PedersenBackground: Rheumatoid arthritis (RA) is a systemic, chronic, autoimmune disease, which affects the joints with inflammation leading to destruction of cartilage and bone. Osteoarthritis (OA) is a degenerative joint disease characterised by low level of chronic inflammation, slow...

  14. Predicting new-onset of postoperative atrial fibrillation in patients undergoing cardiac surgery using semi-automatic reading of perioperative electrocardiograms

    DEFF Research Database (Denmark)

    Gu, Jiwei; Graff, Claus; Melgaard, Jacob

    2015-01-01

    P10 Predicting new-onset of postoperative atrial fibrillation in patients undergoingcardiac surgery using semi-automatic reading of perioperative electrocardiograms. Jiwei Gu, Claus Graff, Jacob Melgaard, Søren Lundbye-Christensen, Erik Berg Schmidt, Christian Torp-Pedersen, Kristinn Thorsteinsson......, Jan Jesper Andreasen. Aalborg, DenmarkBackground: Postoperative new onset atrial fibrillation (POAF) is the most common arrhythmia after cardiac surgery. The aim of this study was to evaluate if semi-automatic readings of perioperative electrocardiograms (ECGs) is of any value in predicting POAF after...... ECG monitoring. A semi-automatic machine capable of reading differentparameters of digitalized ECG’s was used to read both lead specific (P/QRS/T amplitudes/intervals) and global measurements (P-duration/QRS-duration/PR-interval/QT/Heart Rate/hypertrophy).Results: We divided the patients into two...

  15. Nasal cavity dimensions in guinea pig and rat measured by acoustic rhinometry and fluid-displacement method

    DEFF Research Database (Denmark)

    Straszek, Sune; Pedersen, O.F.

    2004-01-01

    The purpose of the study was to measure nasal passageway dimensions in guinea pigs and rats by use of acoustic rhinometry (AR) and by a previously described fluid-displacement method (FDM) (Straszek SP, Taagehoej F, Graff S, and Pedersen OF. J Appl Physiol 95: 635-642, 2003) to investigate...... the potential of AR in pharmacological research with these animals. We measured the area-distance relationships by AR of nasal cavities postmortem in five guinea pigs (Duncan Hartley, 400 g) and five rats (Wistar, 250 g) by using custom-made equipment scaled for the purpose. Nosepieces were made from plastic...... pipette tips and either inserted into or glued onto the nostrils. We used liquid perfluorocarbon in the fluid-displacement study, and it was carried out subsequent to the acoustic measurements. We found for guinea pigs that AR measured a mean volume of 98 mm(3) (95-100 mm(3)) (mean and 95% confidence...

  16. Improved Accuracy of Density Functional Theory Calculations for CO2 Reduction and Metal-Air Batteries

    DEFF Research Database (Denmark)

    Christensen, Rune; Hansen, Heine Anton; Vegge, Tejs

    2015-01-01

    Density functional theory (DFT) calculations have greatly contributed to the atomic level understanding of electrochemical reactions. However, in some cases, the accuracy can be prohibitively low for a detailed understanding of, e.g. reaction mechanisms. Two cases are examined here, i.e. the elec......Density functional theory (DFT) calculations have greatly contributed to the atomic level understanding of electrochemical reactions. However, in some cases, the accuracy can be prohibitively low for a detailed understanding of, e.g. reaction mechanisms. Two cases are examined here, i.......47 eV and 0.17 eV using metals as reference. The presented approach for error identification is expected to be applicable to a very broad range of systems. References: [1] A. A. Peterson, F. Abild-Pedersen, F. Studt, J. Rossmeisl, and J. K. Nørskov, Energy Environ. Sci., 3,1311 (2010) [2] F. Studt, F...

  17. Organ dose and effective dose with the EOS scanner in spine deformity surgery

    DEFF Research Database (Denmark)

    Heide Pedersen, Peter; Petersen, Asger Greval; Eiskjær, Søren Peter

    2016-01-01

    Organ dose and effective dose with the EOS scanner in spine deformity surgery. A study on anthropomorphic phantoms describing patient radiation exposure in full spine examinations. Authors: Peter Heide Pedersen, Asger Greval Petersen, Søren Peter Eiskjær. Background: Ionizing radiation potentially...... quality images while at the same time reducing radiation dose. At our institution we use the EOS for pre- and postoperative full spine examinations. Purpose: The purpose of the study is to make first time organ dose and effective dose evaluations with micro-dose settings in full spine examinations. Our...... hypothesis is that organ dose and effective doses can be reduced 5-10 times compared to standard settings, without too high image-quality trade off, resulting in a theoretical reduction of radiation induced cancer. Methods: Patient dosimetry is performed on anthropomorphic child phantoms, representing a 5...

  18. A Survey on Operator Monotonicity, Operator Convexity, and Operator Means

    Directory of Open Access Journals (Sweden)

    Pattrawut Chansangiam

    2015-01-01

    Full Text Available This paper is an expository devoted to an important class of real-valued functions introduced by Löwner, namely, operator monotone functions. This concept is closely related to operator convex/concave functions. Various characterizations for such functions are given from the viewpoint of differential analysis in terms of matrix of divided differences. From the viewpoint of operator inequalities, various characterizations and the relationship between operator monotonicity and operator convexity are given by Hansen and Pedersen. In the viewpoint of measure theory, operator monotone functions on the nonnegative reals admit meaningful integral representations with respect to Borel measures on the unit interval. Furthermore, Kubo-Ando theory asserts the correspondence between operator monotone functions and operator means.

  19. A mechanism for driving the gross Birkeland current configuration in the auroral oval

    International Nuclear Information System (INIS)

    Rostoker, G.; Bostrom, R.

    1976-01-01

    Birkeland (field-aligned) sheet currents flowing into and out of the auroral oval as reported by Zmuda and Armstrong (1974) are integrally associated with convective motion of plasma in the magnetotail. It is demonstrated that these currents can be driven by energy supplied by the braking of this convective motion of the plasma sheet particles as they drift toward the flanks of the magnetosphere. In the ionosphere the sheet currents close as Pedersen currents, resulting in the dissipation of power, while far from the earth the closure currents, which provide the braking force for the plasma, flow in the plasma sheet approximately normal to the neutral sheet out to radial distances of about 80 R/subE/. During periods of moderate magnetospheric activity the Birkeland currents result in a rate of dissipation of convective energy of the order of 10 GW

  20. The offshore record of variable Cenozoic sediment flux from Western Scandinavia

    DEFF Research Database (Denmark)

    Goledowski, Bartosz; Clausen, O.R.; Nielsen, S.B.

    2009-01-01

    , 2005) to glacial. As, furthermore, glacial erosion (the glacial "buzzsaw" Mitchell and Montgomery, 2006; Brozovic et al., 1997; Pedersen et al, 2008) and periglacial processes (Anderson, 2002) are known to possess the potential for producing characteristic low-relief accordant landscapes at high...... elevation, this hypothesis also provides and alternative to understanding flattish landscape elements in the western Scandinavian highlands, which conventionally have been explained as remnants of uplifted peneplains previously graded to sea level (the Davisian cyclic landscape evolution model). Therefore...... and adjacent sedimentary basins emerges. This hypothesis is to be tested using the present results. Estimation of offshore matrix mass will be the basis for reconstruction of the development of source areas with use of mathematical models of landscape evolution....

  1. Daily marathon running for a week-the biochemical and body compositional effects of participation

    DEFF Research Database (Denmark)

    Karstoft, Kristian; Solomon, Thomas; Laye, Matthew J

    2013-01-01

    Karstoft, K, Solomon, TP, Laye, MJ, and Pedersen, BK. Daily marathon running for a week-The biochemical and body compositional effects of participation. J Strength Cond Res 27(11): 2927-2933, 2013-Although long-distance running, such as ultramarathons and multistage races, is increasingly popular......, it maybe potentially harmful to health, despite sparse evidence. We studied 8 experienced recreational runners participating in a multiple-marathon running event in which 7 marathons were completed on consecutive days. Fasting blood chemistry and body composition were assessed before and 20-24 hours after...... the race. The total finish time for the 7 marathons ranged between 23:25:42 and 34:25:21 (hours:minutes:seconds). Only minor increases in circulating skeletal muscle cell damage markers, liver cell damage markers, and inflammatory markers occurred after the race. No other significant adverse biochemical...

  2. Ethnicities and violence

    DEFF Research Database (Denmark)

    Pedersen, Bodil Maria

    Ethnicities and Violence Bodil Pedersen, University of Roskilde A recent publication (Thiara, Condon and Schröttle 2011) presents and discusses questions concerning diverse forms of violence against women from ethnic minorities in Europe. The issue raises unsolved questions of how to study...... as violence and what meanings do we attribute to it? What meanings does gender and ethnicities have for diverse participants in violent relations? What are their societal consequences and how do we study these? Central is also how we conceptualise and study questions concerning violence in minorised as well...... as against ethnic communities. On one hand our research should allow for conceptualising and studying specific practices in these communities. On the other hand - risking repeating and supporting dominant discourses of gendered violence as characteristic for them – we do not intend to represent them...

  3. COMPOSITION OF STAFF REVIEW ADVISORY BODIES - 2000 COMPOSITION OF THE JOINT TRAINING BOARD (JTB) - 2000/2001

    CERN Multimedia

    HR Division

    2000-01-01

    For the present staff review, the advisory bodies set up to prepare recommendations are composed as follows:Senior Staff Advancement Committee (SSAC)D. Treille / EP (Convener)C. Benvenuti / ESTD. O. Williams /ITTechnical Engineers & Administrative Careers Committee (TEACC) C. Hauviller / EPL. Leistam / ESTS. Jarp / IT [Chairman]F. Pedersen / PSR. Lauckner / SLC. Roche / ETTLong-term contract Boards (LTCBs) (Categories 2 &5a)Tiziano Camporesi / EP [Convener]Florence Ranjard / EP\t[Alternate]Jacques Gruber / PSPeter Sievers / LHCThomas Pettersson / ESTMichel Mayoud / ESTSue Foffano / ASThierry Lagrange / SPLWerner Zapf / HR (Secretary) LTCB 2(Categories 3, 4, 5b & 5c)Véronique Paris / SL [Convener]Fabien Pérriolat / PS\t [Alternate]Mats Wilhelmsson / STVéronique Fassnacht / TISLucie Linssen / EPMichel Mayoud / ESTPatrick Geeraert / FIJohn Cuthbert / HRSeamus Hegarty / HR (Secretary) Composition of the Joint Training Board (JT...

  4. Epioptics-8

    Science.gov (United States)

    Cricenti, Antonio

    2006-03-01

    Preface -- Ab-initio theories for the calculation of excited states properties / O. Pulci ... [et al.] -- Theory of surface second harmonic generation / W. Luis Mochán, Jesś A. Maytorena -- Exitation of multiple plasmon in optical second-harmonic generation / K. Pedersen, T. G. Pedersen, P. Morgen -- Non-linear optical probes of biological surfaces / Mischa Bonn, Volker Knecht, Michiel Müller -- Ab initio study of the Ge(111): Sn surface / Paola Gori, Olivia Pulci, Antonio Cricenti -- Lifetime of excited states / B. Hellsing -- Soliton dynamics in non-commensurate surface structure / Alexander S. Kovalev, Igor V. Gerasimchuk -- Raman scattering as an epioptic probe for low dimensional structures / E. Speiser, K. Fleischer, W. Richter -- Calculation of reflectance anisotropy for semiconductor surface exploration / W. G. Schmidt -- Molecular assembly at metal surfaces studied by reflection anisotropy spectroscopy / David S. Martin -- Study of solid/liquid interfaces by optical techniques / Y. Borensztein -- Surface preparation of Cu(110) for ambient environments / G. E. Isted, N. P. Blanchard, D. S. Martin -- Micro-radiographs stored in lithium fluoride films show strong optical contrast with no topographical contribution / A. Ustione ... [et al.] -- Metal nanofilms studied with infrared spectroscopy / Gerhard Fahsold, Andreas Priebe, Annemarie Pucci -- An AFM investigation of oligonucleotides anchored on an unoxidized crystalline silicon surface / G. Longo ... [et al.] -- A new approach to characterize polymeric nanofilters contamination using scanning near-field optical microscopy / C. Oliva ... [et al.] -- Magnetization reversal processes in Fe/NiO/Fe(001) trilayers studied by means of magneto-optical Kerr effect / P. Biagioni -- Laser-induced band bending variation for ZnTe (110)1x1 surface / S. D. Thorpe ... [et al.] -- Optical properties of materials in an undergraduate physics curriculum / Julio R. Blanco.

  5. Field-aligned current signatures in the near-tail region. 2. Coupling between the region 1 and region 2 systems

    International Nuclear Information System (INIS)

    Ohtani, S.; Kokubun, S.; Nakamura, R.; Elphic, R.C.; Russell, C.T.; Baker, D.N.

    1990-01-01

    The development of the substorm-associated current system in the near-tail region is examined in the light of both experiment and theory. First, the March 28, 1979, event is examined intensively by using ground magnetometer data and satellite magnetic field and energetic particle data. The comparison of field-aligned current signatures at geosynchronous altitude and in the near-tail region indicates that the development of the region 1 system is not merely the enhancement in current intensity of the pre-existing system. This finding is consistent with the so-called current wedge model, in which the tail current is converted into a pair of field-aligned currents with the region 1 polarity at substorm onsets. Detailed inspection, however, suggests that the region 2 system is as important as the region 1 system. Statistical properties of the azimuthal magnetic component at synchronous orbit indicate that the deviation during disturbed periods is larger than expected from the enhancement of the region 1 current. These individual and statistical studies suggest that the region 2 system tends to develop in the synchronous region and that the coupling between the region 1 and the region 2 systems is important. The current closure in the magnetosphere is discussed from a viewpoint of the macroscopic behavior of plasma. It is suggested that the dawnside and the duskside region 2 currents are closed in the magnetosphere by the curvature current during the growth phase and by the magnetic gradient current during the expansion phase. The field-aligned currents of the region 1 and the region 2 systems are closed in the ionosphere by the Pedersen current. Consequently, the energy is dissipated as the Joule heating and this energy must be supplied from the magnetosphere. Therefore, the counter part of the Pedersen current, which closes the region 1 and the region 2 currents in magnetosphere, must be the dynamo current

  6. Magnetosphere-thermosphere coupling: An experiment in interactive modeling

    International Nuclear Information System (INIS)

    Forbes, J.M.; Harel, M.

    1989-01-01

    The Rice convection model (RCM) is utilized to investigate the electrodynamic coupling between the inner magnetosphere and the thermosphere including the effects of EUV- and convection-driven neutral winds under quasi-equilibrium conditions. A unique aspect of the study is that the convection-driven winds are included self-consistently and interactively; that is, a steady state wind parameterization is written analytically in terms of the electrostatic potential, which is in turn included in a closed-loop calculation for the electric potential itself. Simulations are performed from 1,400 UT to 1,600 UT during the CDAW-6 interval on March 22, 1979, when the cross-cap electric potential attains values of order 140-180 kV. During the early phases of the disturbance when the normal shielding from high latitudes breaks down, the neutral winds do not modify appreciably the disturbance electric fields at middle and low latitudes. As the system approaches a quasi-equilibrium state, the neutral winds play a much more significant role. The convection driven component of the neutral wind similarly acts to reduce the southward field in the noon sector, but gives rise to an enhancement in the dusk sector field extending to middle latitudes. The parameterized Pedersen effective winds are of order 300 ms -1 and reflect the familiar two-cell pattern with antisunward flow over the polar cap and return flows in the dawn and dusk sectors. These amplitudes and similarity with the ion drift motions reflect the relatively large contributions to the Pedersen effective winds originating in the upper E region and lower F region of the ionosphere. Possibilities for introducing further sophistication into the wind parameterization are discussed, as well as ramifications of the present study on the possible merging of the RCM with the NCAR TGCM to attain a higher degree of self-consistency and reality in modelling efforts

  7. Response of the lower ionosphere to the great solar flare of August 7, 1972

    Energy Technology Data Exchange (ETDEWEB)

    Sato, T [Hyogo Coll. of Medicine, Hyogo (Japan)

    1975-01-01

    The response of the ionosphere in an altitude range of 50--200 km to the great solar flare that occurred at about 1500 UT on 7 August 1972 is studied. Sudden increases in electron concentration, Pedersen and Hall electric conductivities (SIEC), total electron content (SITEC) and sudden cosmic noise absorption (SCNA) due to solar x-ray flux increments at 1530, 1600, 1700 and 2100 UT are calculated for the location of 40/sup 0/N latitude and 75/sup 0/W longitude, and some of the results are compared with observed values. The solar X-ray emissions concerned in this study are those with wavelengths of 1--100 A, of which emission fluxes measured from the SOLRAD 10 satellite are available for the 1--20 A band, while emission spectra for other wavelength bands are assumed. Two altitude profiles of increased electron concentrations at each time are first derived based on two assumed effective recombination coefficient profiles, then associated increments in 30 MHz cosmic noise absorption and Pedersen and Hall electric conductivities are derived. It is found that the calculated 30 MHz SCNA's (SCNA values) and SITEC's (50--200 km) at 1530, 1600 and 1700 UT for one of the increased electron concentration profiles are in reasonably good agreement with the observed ones, but the SITEC's roughly corrected for the entire ionosphere at 1530 and 1600 UT seem to be greater by more than 20 and 30% than the observed ones, respectively. These results seem to imply that the derived electron concentration enhancements in the ionosphere above about 100 km are overestimated.

  8. Growth analysis of Fafia in relation to the propagation method used Análise de crescimento de fáfia em função do tipo de propagação

    Directory of Open Access Journals (Sweden)

    André May

    2008-09-01

    Full Text Available A trial was carried out in Campinas, Brazil, from August 2005 to August 2006, in order to analyze the effect of two propagation methods (seeds and cuttings on the development of Pfaffia glomerata (Spreng. Pedersen. The experimental design was a completely randomized block, with five replications, and two methods of plant propagation. Plant height, aerial part dry mass and root dry mass were evaluated. Plants propagated from cuttings showed greater accumulation of dry mass on the aerial part. Root dry mass accumulation curves showed an exponential pattern, and at the end of the experimental period, the average of roots dry mass for both treatments were similar, up to 349,65 g plant-1.Neste trabalho, realizado no Instituto Agronômico, em Campinas-SP, de agosto/05 a agosto/06, estudou-se a influência de dois tipos de propagação no desenvolvimento de Pfaffia glomerata (Spreng. Pedersen. O delineamento experimental utilizado foi inteiramente casualizado com cinco repetições, sendo nos tratamentos, estudadas duas formas de propagação da planta (semente e estacas. Foi avaliada a altura da planta, massa seca da parte aérea e massa seca da raiz. As plantas propagadas por estaca apresentaram maior acúmulo de massa seca da parte aérea comparativamente àquelas propagadas por sementes. As curvas de acúmulo de massa seca da raiz apresentaram comportamento exponencial, sendo que, ao final do período experimental, a produção de raízes foi semelhante para os dois tratamentos estudados, atingindo valores de até 349,65 g planta-1 de massa seca da raiz.

  9. Rocket observations at the northern edge of the eastward electrojet

    International Nuclear Information System (INIS)

    Cahill, L.J. Jr.; Arnoldy, R.L.; Taylor, W.W.L.

    1980-01-01

    A Nike-Tomahawk rocket was launched north over two quiet, late evening auroral arcs in March 1975. A northward magnetic disturbance was observed on the ground under the rocket trajectory. South of the arcs the northward electric field was 60 mV/m, indicating strong westward plasma flow. An eastward electrojet current layer was penetrated in the upward flight. Precipitating electrons were observed over each arc. The electric field decreased to below 20 mV/m over each arc and recovered to 50 mV/m between the arcs. Using the observed electron flux and a model of the ionosphere, the Hall and Pedersen conductivities were calculated. These conductivities were used, with the observed electric field, to calculate the eastward and northward components of the horizontal ionospheric currents. The eastward current calculated south of the first arc agreed well with the observed eastward electrojet current. The power dissipated by the Pedersen current Σ/sub p/EPSILON 2 was also calculated and compared with the power carried by the precipitating electrons. The Joule power decreased abruptly in the auroral arcs, as the pricipitating electron power increased. The total dissipated power was approximately the same inside the arcs, between them, and south of the luminosity. North of the aurora the electric field and dissipated power remained low. Field-aligned currents carried by the observed electrons were about a factor of 3 lower than those inferred from the magnetic field measurements. Likewise, current continuity arguments to keep the auroral current system divergence free required a larger field-aligned current than that obtained from the particle detectors

  10. Irritable bowel symptoms and the development of common mental disorders and functional somatic syndromes identified in secondary care – a long-term, population-based study

    Directory of Open Access Journals (Sweden)

    Poulsen CH

    2017-07-01

    Full Text Available Chalotte Heinsvig Poulsen,1,2 Lene Falgaard Eplov,2 Carsten Hjorthøj,2 Marie Eliasen,1 Sine Skovbjerg,1 Thomas Meinertz Dantoft,1 Andreas Schröder,3 Torben Jørgensen1,4,5 1Research Centre for Prevention and Health, Capital Region of Denmark, Glostrup, 2Copenhagen University Hospital, Mental Health Centre Copenhagen, Hellerup, 3Research Clinic for Functional Disorders and Psychosomatics, Aarhus University Hospital, Aarhus, 4Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 5The Faculty of Medicine, Aalborg University, Aalborg, Denmark Objective: Irritable bowel syndrome (IBS is associated with mental vulnerability, and half of patients report comorbid somatic and mental symptoms. We aimed to investigate the relationship between an IBS symptom continuum and the subsequent development of common mental disorders (CMDs and functional somatic syndromes (FSSs.Methods and study design: A longitudinal population-based study comprising two 5-year follow-up studies, Dan-MONICA 1 (1982–1987 and Inter99 (1999–2004, recruited from the western part of Copenhagen County. The total study population (n = 7,278 was divided into symptom groups according to the degree of IBS definition fulfillment at baseline and/or follow-up and was followed until December 2013 in Danish central registries. Cox regression was used for the analyses, adjusting for age, sex, length of education and cohort membership. In a subsequent analysis, we adjusted for mental vulnerability as a risk factor for both CMDs and FSSs, including IBS.Results: Over a 5-year period, 51% patients had no IBS symptoms, 17% patients had IBS symptoms without abdominal pain, 22% patients had IBS symptoms including abdominal pain and 10% patients fulfilled the IBS definition. IBS and IBS symptoms including abdominal pain were significantly associated with the development of CMDs and other FSSs identified in secondary care. When adjusting for mental

  11. A retrograde y-stenting of the trachea for treatment of mediastinal fistula in an unusual situation

    Directory of Open Access Journals (Sweden)

    Hohenforst-Schmidt W

    2017-05-01

    Full Text Available Wolfgang Hohenforst-Schmidt,1 Paul Zarogoulidis,2 Michael Steinheimer,1 Thomas Schneider,1 Naim Benhassen,1 Holger Rupprecht,3 Lutz Freitag4 1Medical Clinic I, “Fuerth” Hospital, University of Erlangen, Fuerth, Germany; 2Pulmonary Department-Oncology Unit, “G Papanikolaou” General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece; 3Department of General, Vascular and Thoracical Surgery, “Fuerth” Hospital, University of Erlangen, Fuerth, 4Department of Interventional Pneumology, Ruhrlandklinik, University Hospital Essen, University of Essen-Duisburg, Essen, Germany Introduction: Stents have been used for quite some time for the treatment of benign and malignant airway stenosis. Silicon stents are preferred for benign situations, whereas metallic self-expanding stents are preferred for malignant comorbidities.Patient and methods: In general, stents can be placed in different approach directions, although in pulmonary medicine it is logical to apply only antegrade techniques – until now. A 63-year-old patient, 168 cm height and 53 kg weight on referral, suffered chronical diseases. The patient was diagnosed with a papillary thyroid carcinoma in 1989, which was treated by resection and radiotherapy. In the following years, she developed a stenosis of the esophagus. The decision to try endobronchial stenting was made upon the plan to close that fistula with a pedicled omentum majus replacement through the diaphragmal opening of the esophagus. This surgical plastic needed an abutment and a secured continuous airway replacement above the tracheostoma level. A Freitag stent (FS, 11 cm in length (110–25–40 and an inner diameter of 13 mm, was placed successfully retrograde into the trachea and completely bridged the big fistula. Unfortunately the patient passed away due to pulmonary infections after several weeks.Discussion: In this case report, a successful but unusual case of retrograde stent placement of a modified

  12. Photovoltaic conference on research and innovation

    International Nuclear Information System (INIS)

    Moisan, Francois; Huennekes, Christoph; Malbranche, Philippe; Neuhaus, Holger; Lincot, Daniel; Dimroth, Frank; Signamarcheix, Thomas; Baudrit, Mathieu; Wasselin, Jocelyne; Franz, Oliver; Lippert, Michael; Bena, Michel

    2013-01-01

    The French-German office for Renewable energies (OFAEnR) organised a conference on photovoltaic research and innovation. In the framework of this French-German exchange of experience, about 80 participants exchanged views on PV research priorities and on the possible cooperation paths capable to meet the challenges of an increasing worldwide competition. Beside the analysis of national and European support programmes, the presentations addressed also the technological advances in the domain of energy efficiency and fabrication of PV systems, but also the energy storage solutions and the problems of integration to grids. This document brings together the available presentations (slides) made during this event: 1 - Photovoltaic R and D financing in France (Francois Moisan); 2 - Research consortia: research promotion in Germany (Christoph Huennekes); 3 - EeRA Joint research Programme Photovoltaic Solar energy: cooperation support to PV research at the European level (Philippe Malbranche); 4 - The Research Project 'SONNe' - A shining example within the German Funding Scheme 'Innovation Alliance' (Holger Neuhaus); 5 - The 'Ile de France Photovoltaic Institute': a huge cooperation between academic and industrial partners for the improvement of photovoltaic energy efficiency and competitiveness (Daniel Lincot); 6 - SOLARBOND the basis for a successful French-German collaboration (Frank Dimroth); 7 - Smart Country model project: Successful integration of distributed generation in rural areas - Smart integration of PV power generation thanks to the combination with a modified biogas storage system (Oliver Franz); 8 - Sol-ion Conversion, storage and management of residential PV energy (Michael Lippert); 9 - Improving Tools to massively integrate Renewables in the European electric System (Michel Bena)

  13. Evaluation of oxygen species during E-H transition in inductively coupled RF plasmas: combination of experimental results with global model

    Science.gov (United States)

    Meichsner, Jürgen; Wegner, Thomas

    2018-05-01

    Inductively coupled RF plasmas (ICP) in oxygen at low pressure have been intensively studied as a molecular and electronegative model system in the last funding period of the Collaborative Research Centre 24 "Fundamentals of Complex Plasmas". The ICP configuration consists of a planar coil inside a quartz cylinder as dielectric barrier which is immersed in a large stainless steel vacuum chamber. In particular, the E-H mode transition has been investigated, combining experimental results from comprehensive plasma diagnostics as input for analytical rate equation calculation of a volume averaged global model. The averaged density was determined for electrons, negative ions O-, molecular oxygen ground state O2(X3 Σg-) and singlet metastable state O2(a1 Δg) from line-integrated measurements using 160 GHz Gaussian beam microwave interferometry coupled with laser photodetachment experiment and VUV absorption spectroscopy, respectively. Taking into account the relevant elementary processes and rate coefficients from literature together with the measured temperatures and averaged density of electrons, O2(X3 Σg-) and O2(a1 Δg) the steady state density was calculated for O(3P), O2(b1 Σg+), O(1D), O(1S), O3, O-, O2-, and O3-, respectively. The averaged density of negative ions O- from the rate equation calculation is compared with the measured one. The normalized source and loss rates are discussed for O(3P), O2(b1 Σg+) and O-. Contribution to the Topical Issue "Fundamentals of Complex Plasmas", edited by Jürgen Meichsner, Michael Bonitz, Holger Fehske, Alexander Piel.

  14. [History of gold--with danish contribution to tuberculosis and rheumatoid arthritis].

    Science.gov (United States)

    Norn, Svend; Permin, Henrik; Kruse, Poul R; Kruse, Edith

    2011-01-01

    Gold has a long history as a therapeutic agent, first as gold particles and colloidal gold, then as a soluble salt made by the alchemists, and potable gold was recommended almost as a panacea against different diseases. Gold compounds were introduced in the treatment of tuberculosis, based initially on the reputation of Robert Koch, who found gold cyanide effective against Mycobacterium tuberculosis in cultures. Although several investigations of gold salts showed no convincing effect in experimental tuberculosis in guinea pigs, the idea of using gold compounds as chemotherapy was furthermore encouraged from the work of Paul Ehrlich with arsenicals. The enthusiasm and the craving desperately for a remedy for tuberculosis forced Danish physicians, in the mid-1920s to treat tuberculosis with Sanocrysin (gold sodium thiosulfate). Professor Holger Møllgaard, in collaboration with the clinicians the professors Knud Secher and Knud Faber, was the theoretical promoter of the project. He recommended sanocrysin-antiserum therapy, since sanocrysin caused serious reactions in tuberculosis animals, possible by releasing toxins from tubercle bacilli "killed" by sanocrysin. However the enthusiastic response to sanocrysin in Europe declined along by controlled trials and reports on toxicity in the 1930s. The belief that rheumatoid arthritis was a form of tuberculosis caused a renaissance in chrysotherapy. In France Jacques Forestier obtained encouraging results in the treatment of rheumatoid arthritis with myochrysine and other gold salts, and he pointed out the disease modifying effect of chrysotherapy. In Denmark Knud Secher, who was the clinical initiator of Sanocrysin therapy in tuberculosis, now became the founder of chrysotherapy in rheumatoid arthritis. Although new potential agents are now taking over in the treatment of arthritis, it is still believed, that there is a place for the chrysotherapy. However a new future for gold, in the form of nanoparticles, appears on

  15. The clinical outcome and microbiological profile of bone-anchored hearing systems (BAHS) with different abutment topographies: a prospective pilot study.

    Science.gov (United States)

    Trobos, Margarita; Johansson, Martin Lars; Jonhede, Sofia; Peters, Hanna; Hoffman, Maria; Omar, Omar; Thomsen, Peter; Hultcrantz, Malou

    2018-06-01

    In this prospective clinical pilot study, abutments with different topologies (machined versus polished) were compared with respect to the clinical outcome and the microbiological profile. Furthermore, three different sampling methods (retrieval of abutment, collection of peri-abutment exudate using paper-points, and a small peri-abutment soft-tissue biopsy) were evaluated for the identification and quantification of colonising bacteria. Twelve patients, seven with machined abutment and five with polished abutment, were included in the analysis. Three different sampling procedures were employed for the identification and quantification of colonising bacteria from baseline up to 12 months, using quantitative culturing. Clinical outcome measures (Holgers score, hygiene, pain, numbness and implant stability) were investigated. The clinical parameters, and total viable bacteria per abutment or in tissue biopsies did not differ significantly between the polished and machined abutments. The total CFU/mm 2 abutment and CFU/peri-abutment fluid space of anaerobes, aerobes and staphylococci were significantly higher for the polished abutment. Anaerobic bacteria were detected in the tissue biopsies before BAHS implantation. Anaerobes and Staphylococcus spp. were detected in all three compartments after BAHS installation. For most patients (10/12), the same staphylococcal species were found in at least two of the three compartments at the same time-point. The common skin coloniser Staphylococcus epidermidis was identified in all patients but one (11/12), whereas the pathogen Staphylococcus aureus was isolated in five of the patients. Several associations between clinical and microbiological parameters were found. There was no difference in the clinical outcome with the use of polished versus machined abutment at 3 and 12 months after implantation. The present pilot trial largely confirmed a suitable study design, sampling and analytical methodology to determine the effects

  16. 2. symposium energy crops 2009; 2. Symposium Energiepflanzen 2009

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-27

    Within the meeting '2nd Symposium energy plants 2009', held at 17th to 18th November, 2009, in Berlin (Federal Republic of Germany), the following lectures were held: (1) The bio energy policy of the Federal Government in the area of attention between climatic protection, ecology and economy (Ilse Aigner); (2) Chances and threatens of cultivation of energy plants for a sustainable energy supply (Alois Heissenhuber); (3) Certification as a prerequisite of the global exploration of bio energy (Andreas Feige); (4) A project support in the field of cultivation of energy plants, a review (Andreas Schuette); (5) Results from the investigation of the crop rotation in the EVA network (Armin Vater); (6) Optimisation of the cultivation technology of sorghum millets (Christian Roehricht); (7) The two-culture utilization system - a comparison between ecologic and conventional cultivation (Reinhold Stuelpnagel); (8) Crop rotation with energy plants - Chances and threatens for the plant protection (Baerbel Gerowitt); (9) Efficiency of utilization of water for energy plants (Siegfried Schittenhelm); (10) Utilization of arable food grasses and permanent grassland as a substrate for biogas (Matthias Benke); (11) Economical evaluation of plant fermentation substrates (Dominik Reus); (12) Energy plants as a challenge for the agricultural engineering (Heiner Bruening); (13) Influence of the design of cultivation on the subsequent effects of the cultivation of energy plants (Michael Glemnitz); (14) Energy plants and waters protection - Key aspects and possible options of action (Heike Nitsch); (15) Neophytes as energy plants - Chances and threatens (Werner Kuhn); (16) Manifold in te landscape - extensive cultivation systems with renewable raw materials as an option for nature protection? (Peer Heck); (17) Ecologic aspects of agro forestry systems (Holger Gruenewald); (18) Enhancement of the potential of energy yield of winter wheat (Wolfgang Friedt); (19) Interspersed silphie

  17. Glutathione peroxidase mimic ebselen improves glucose-stimulated insulin secretion in murine islets.

    Science.gov (United States)

    Wang, Xinhui; Yun, Jun-Won; Lei, Xin Gen

    2014-01-10

    Glutathione peroxidase (GPX) mimic ebselen and superoxide dismutase (SOD) mimic copper diisopropylsalicylate (CuDIPs) were used to rescue impaired glucose-stimulated insulin secretion (GSIS) in islets of GPX1 and(or) SOD1-knockout mice. Ebselen improved GSIS in islets of all four tested genotypes. The rescue in the GPX1 knockout resulted from a coordinated transcriptional regulation of four key GSIS regulators and was mediated by the peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1α)-mediated signaling pathways. In contrast, CuDIPs improved GSIS only in the SOD1 knockout and suppressed gene expression of the PGC-1α pathway. Islets from the GPX1 and(or) SOD1 knockout mice provided metabolically controlled intracellular hydrogen peroxide (H2O2) and superoxide conditions for the present study to avoid confounding effects. Bioinformatics analyses of gene promoters and expression profiles guided the search for upstream signaling pathways to link the ebselen-initiated H2O2 scavenging to downstream key events of GSIS. The RNA interference was applied to prove PGC-1α as the main mediator for that link. Our study revealed a novel metabolic use and clinical potential of ebselen in rescuing GSIS in the GPX1-deficient islets and mice, along with distinct differences between the GPX and SOD mimics in this regard. These findings highlight the necessities and opportunities of discretional applications of various antioxidant enzyme mimics in treating insulin secretion disorders. REBOUND TRACK: This work was rejected during standard peer review and rescued by Rebound Peer Review (Antioxid Redox Signal 16: 293-296, 2012) with the following serving as open reviewers: Regina Brigelius-Flohe, Vadim Gladyshev, Dexing Hou, and Holger Steinbrenner.

  18. Impact of volume and surface processes on the pre-ionization of dielectric barrier discharges: advanced diagnostics and fluid modeling

    Science.gov (United States)

    Nemschokmichal, Sebastian; Tschiersch, Robert; Höft, Hans; Wild, Robert; Bogaczyk, Marc; Becker, Markus M.; Loffhagen, Detlef; Stollenwerk, Lars; Kettlitz, Manfred; Brandenburg, Ronny; Meichsner, Jürgen

    2018-05-01

    The phenomenology and breakdown mechanism of dielectric barrier discharges are strongly determined by volume and surface memory effects. In particular, the pre-ionization provided by residual species in the volume or surface charges on the dielectrics influences the breakdown behavior of filamentary and diffuse discharges. This was investigated by advanced diagnostics such as streak camera imaging, laser photodetachment of negative ions and laser photodesorption of electrons from dielectric surfaces in correlation with 1D fluid modeling. The streak camera images show that an increasing number of residual charges in the volume changes the microdischarge breakdown in air-like gas mixtures from a cathode-directed streamer to a simultaneous propagation of cathode- and anode-directed streamers. In contrast, seed electrons are important for the pre-ionization if the density of residual charges in the volume is low. One source of seed electrons are negative ions, whose density exceeds the electron density during the pre-phase of diffuse helium-oxygen barrier discharges as indicated by the laser photodetachment experiments. Electrons desorbed from the cathodic dielectric have an even larger influence. They induce a transition from the glow-like to the Townsend-like discharge mode in nominally pure helium. Apart from analyzing the importance of the pre-ionization for the breakdown mechanism, the opportunities for manipulating the lateral structure and discharge modes are discussed. For this purpose, the intensity and diameter of a diffuse discharge in helium are controlled by an illuminated semiconducting barrier. Contribution to the Topical Issue "Fundamentals of Complex Plasmas", edited by Jürgen Meichsner, Michael Bonitz, Holger Fehske, Alexander Piel.

  19. A three-dimensional, iterative mapping procedure for the implementation of an ionosphere-magnetosphere anisotropic Ohm's law boundary condition in global magnetohydrodynamic simulations

    Directory of Open Access Journals (Sweden)

    M. L. Goodman

    Full Text Available The mathematical formulation of an iterative procedure for the numerical implementation of an ionosphere-magnetosphere (IM anisotropic Ohm's law boundary condition is presented. The procedure may be used in global magnetohydrodynamic (MHD simulations of the magnetosphere. The basic form of the boundary condition is well known, but a well-defined, simple, explicit method for implementing it in an MHD code has not been presented previously. The boundary condition relates the ionospheric electric field to the magnetic field-aligned current density driven through the ionosphere by the magnetospheric convection electric field, which is orthogonal to the magnetic field B, and maps down into the ionosphere along equipotential magnetic field lines. The source of this electric field is the flow of the solar wind orthogonal to B. The electric field and current density in the ionosphere are connected through an anisotropic conductivity tensor which involves the Hall, Pedersen, and parallel conductivities. Only the height-integrated Hall and Pedersen conductivities (conductances appear in the final form of the boundary condition, and are assumed to be known functions of position on the spherical surface R=R1 representing the boundary between the ionosphere and magnetosphere. The implementation presented consists of an iterative mapping of the electrostatic potential ψ the gradient of which gives the electric field, and the field-aligned current density between the IM boundary at R=R1 and the inner boundary of an MHD code which is taken to be at R2>R1. Given the field-aligned current density on R=R2, as computed by the MHD simulation, it is mapped down to R=R1 where it is used to compute ψ by solving the equation that is the IM Ohm's law boundary condition. Then ψ is mapped out

  20. Hexokinase-2 bound to mitochondria: Cancer's stygian link to the “Warburg effect” and a pivotal target for effective therapy☆

    Science.gov (United States)

    Mathupala, Saroj P.; Ko, Young H.; Pedersen, Peter L.

    2009-01-01

    The most common metabolic hallmark of malignant tumors, i.e., the “Warburg effect” is their propensity to metabolize glucose to lactic acid at a high rate even in the presence of oxygen. The pivotal player in this frequent cancer phenotype is mitochondrial-bound hexokinase [Bustamante E, Pedersen PL. High aerobic glycolysis of rat hepatoma cells in culture: role of mitochondrial hexokinase. Proc Natl Acad Sci USA 1977;74(9):3735−9; Bustamante E, Morris HP, Pedersen PL. Energy metabolism of tumor cells. Requirement for a form of hexokinase with a propensity for mitochondrial binding. J Biol Chem 1981;256(16):8699−704]. Now, in clinics worldwide this prominent phenotype forms the basis of one of the most common detection systems for cancer, i.e., positron emission tomography (PET). Significantly, HK-2 is the major bound hexokinase isoform expressed in cancers that exhibit a “Warburg effect”. This includes most cancers that metastasize and kill their human host. By stationing itself on the outer mitochondrial membrane, HK-2 also helps immortalize cancer cells, escapes product inhibition and gains preferential access to newly synthesized ATP for phosphorylating glucose. The latter event traps this essential nutrient inside the tumor cells as glucose-6-P, some of which is funneled off to serve as carbon precursors to help promote the production of new cancer cells while much is converted to lactic acid that exits the cells. The resultant acidity likely wards off an immune response while preparing surrounding tissues for invasion. With the re-emergence and acceptance of both the “Warburg effect” as a prominent phenotype of most clinical cancers, and “metabolic targeting” as a rational therapeutic strategy, a number of laboratories are focusing on metabolite entry or exit steps. One remarkable success story [Ko YH, Smith BL, Wang Y, Pomper MG, Rini DA, Torbenson MS, et al. Advanced cancers: eradication in all cases using 3-bromopyruvate therapy to

  1. Ionospheric feedback effects on the quasi-stationary coupling between LLBL and postnoon/evening discrete auroral arcs

    Directory of Open Access Journals (Sweden)

    M. M. Echim

    2008-05-01

    Full Text Available We discuss a model for the quasi-stationary coupling between magnetospheric sheared flows in the dusk sector and discrete auroral arcs, previously analyzed for the case of a uniform height-integrated Pedersen conductivity (ΣP. Here we introduce an ionospheric feedback as the variation of ΣP with the energy flux of precipitating magnetospheric electrons (εem. One key-component of the model is the kinetic description of the interface between the duskward LLBL and the plasma sheet that gives the profile of Φm, the magnetospheric electrostatic potential. The velocity shear in the dusk LLBL plays the role of a generator for the auroral circuit closing through Pedersen currents in the auroral ionosphere. The field-aligned current density, j||, and the energy flux of precipitating electrons are given by analytic functions of the field-aligned potential drop, ΔΦ, derived from standard kinetic models of the adiabatic motion of particles. The ionospheric electrostatic potential, Φi (and implicitely ΔΦ is determined from the current continuity equation in the ionosphere. We obtain values of ΔΦ of the order of kilovolt and of j|| of the order of tens of μA/m2 in thin regions of the order of several kilometers at 200 km altitude. The spatial scale is significantly smaller and the peak values of ΔΦ, j|| and εem are higher than in the case of a uniform ΣP. Effects on the postnoon/evening auroral arc electrodynamics due to variations of dusk LLBL and solar wind dynamic and kinetic pressure are discussed. In thin regions (of the order of kilometer embedding the maximum of ΔΦ we evidence a non-linear regime of the current-voltage relationship. The model predicts also that visible arcs form when the velocity shear in LLBL is above a threshold value depending on the generator and ionospheric plasma properties. Brighter arcs are obtained for increased velocity shear in the LLBL; their spatial scale remains virtually unmodified. The field

  2. Coupled rotational dynamics of Jupiter's thermosphere and magnetosphere

    Directory of Open Access Journals (Sweden)

    C. G. A. Smith

    2009-01-01

    Full Text Available We describe an axisymmetric model of the coupled rotational dynamics of the thermosphere and magnetosphere of Jupiter that incorporates self-consistent physical descriptions of angular momentum transfer in both systems. The thermospheric component of the model is a numerical general circulation model. The middle magnetosphere is described by a simple physical model of angular momentum transfer that incorporates self-consistently the effects of variations in the ionospheric conductivity. The outer magnetosphere is described by a model that assumes the existence of a Dungey cycle type interaction with the solar wind, producing at the planet a largely stagnant plasma flow poleward of the main auroral oval. We neglect any decoupling between the plasma flows in the magnetosphere and ionosphere due to the formation of parallel electric fields in the magnetosphere. The model shows that the principle mechanism by which angular momentum is supplied to the polar thermosphere is meridional advection and that mean-field Joule heating and ion drag at high latitudes are not responsible for the high thermospheric temperatures at low latitudes on Jupiter. The rotational dynamics of the magnetosphere at radial distances beyond ~30 RJ in the equatorial plane are qualitatively unaffected by including the detailed dynamics of the thermosphere, but within this radial distance the rotation of the magnetosphere is very sensitive to the rotation velocity of the thermosphere and the value of the Pedersen conductivity. In particular, the thermosphere connected to the inner magnetosphere is found to super-corotate, such that true Pedersen conductivities smaller than previously predicted are required to enforce the observed rotation of the magnetosphere within ~30 RJ. We find that increasing the Joule heating at high latitudes by adding a component due to rapidly fluctuating electric fields is unable to explain the high equatorial temperatures. Adding a component of Joule

  3. Seasonal-longitudinal variability of equatorial plasma bubbles

    Directory of Open Access Journals (Sweden)

    W. J. Burke

    2004-09-01

    Full Text Available We compare seasonal and longitudinal distributions of more than 8300 equatorial plasma bubbles (EPBs observed during a full solar cycle from 1989-2000 with predictions of two simple models. Both models are based on considerations of parameters that influence the linear growth rate, γRT, of the generalized Rayleigh-Taylor instability in the context of finite windows of opportunity available during the prereversal enhancement near sunset. These parameters are the strength of the equatorial magnetic field, Beq, and the angle, α, it makes with the dusk terminator line. The independence of α and Beq from the solar cycle phase justifies our comparisons.

    We have sorted data acquired during more than 75000 equatorial evening-sector passes of polar-orbiting Defense Meteorological Satellite Program (DMSP satellites into 24 longitude and 12 one-month bins, each containing ~250 samples. We show that: (1 in 44 out of 48 month-longitude bins EPB rates are largest within 30 days of when α=0°; (2 unpredicted phase shifts and asymmetries appear in occurrence rates at the two times per year when α≈0°; (3 While EPB occurrence rates vary inversely with Beq, the relationships are very different in regions where Beq is increasing and decreasing with longitude. Results (2 and (3 indicate that systematic forces not considered by the two models can become important. Damping by interhemispheric winds appears to be responsible for phase shifts in maximum rates of EPB occurrence from days when α=0°. Low EPB occurrence rates found at eastern Pacific longitudes suggest that radiation belt electrons in the drift loss cone reduce γRT by enhancing E-layer Pedersen conductances. Finally, we analyze an EPB event observed during a magnetic storm at a time and place where α≈-27°, to illustrate how electric-field penetration from

  4. Electrodynamics of an omega-band as deduced from optical and magnetometer data

    Directory of Open Access Journals (Sweden)

    H. Vanhamäki

    2009-09-01

    Full Text Available We investigate an omega-band event that took place above northern Scandinavia around 02:00–02:30 UT on 9 March 1999. In our analysis we use ground based magnetometer, optical and riometer measurements together with satellite based optical images. The optical and riometer data are used to estimate the ionospheric Hall and Pedersen conductances, while ionospheric equivalent currents are obtained from the magnetometer measurements. These data sets are used as input in a local KRM calculation, which gives the ionospheric potential electric field as output, thus giving us a complete picture of the ionospheric electrodynamic state during the omega-band event. The overall structure of the electric field and field-aligned current (FAC provided by the local KRM method are in good agreement with previous studies. Also the E×B drift velocity calculated from the local KRM solution is in good qualitative agreement with the plasma velocity measured by the Finnish CUTLASS radar, giving further support for the new local KRM method. The high-resolution conductance estimates allow us to discern the detailed structure of the omega-band current system. The highest Hall and Pedersen conductances, ~50 and ~25 S, respectively, are found at the edges of the bright auroral tongue. Inside the tongue, conductances are somewhat smaller, but still significantly higher than typical background values. The electric field shows a converging pattern around the tongues, and the field strength drops from ~40 mV/m found at optically dark regions to ~10 mV/m inside the areas of enhanced conductivity. Downward FAC flow in the dark regions, while upward currents flow inside the auroral tongue. Additionally, sharp conductance gradients at the edge of an auroral tongue are associated with narrow strips of intense FACs, so that a strip of downward current flows at the eastern (leading edge and a similar strip of upward current is present at the western (trailing edge. The Joule

  5. Ionospheric feedback effects on the quasi-stationary coupling between LLBL and postnoon/evening discrete auroral arcs

    Directory of Open Access Journals (Sweden)

    M. M. Echim

    2008-05-01

    Full Text Available We discuss a model for the quasi-stationary coupling between magnetospheric sheared flows in the dusk sector and discrete auroral arcs, previously analyzed for the case of a uniform height-integrated Pedersen conductivity (ΣP. Here we introduce an ionospheric feedback as the variation of ΣP with the energy flux of precipitating magnetospheric electrons (εem. One key-component of the model is the kinetic description of the interface between the duskward LLBL and the plasma sheet that gives the profile of Φm, the magnetospheric electrostatic potential. The velocity shear in the dusk LLBL plays the role of a generator for the auroral circuit closing through Pedersen currents in the auroral ionosphere. The field-aligned current density, j||, and the energy flux of precipitating electrons are given by analytic functions of the field-aligned potential drop, ΔΦ, derived from standard kinetic models of the adiabatic motion of particles. The ionospheric electrostatic potential, Φi (and implicitely ΔΦ is determined from the current continuity equation in the ionosphere. We obtain values of ΔΦ of the order of kilovolt and of j|| of the order of tens of μA/m2 in thin regions of the order of several kilometers at 200 km altitude. The spatial scale is significantly smaller and the peak values of ΔΦ, j|| and εem are higher than in the case of a uniform ΣP. Effects on the postnoon/evening auroral arc electrodynamics due to variations of dusk LLBL and solar wind dynamic and kinetic pressure are discussed. In thin regions (of the order of kilometer embedding the maximum of ΔΦ we evidence a non-linear regime of the current-voltage relationship. The model predicts also that visible arcs form when the velocity shear in LLBL is above a threshold value depending on the generator and

  6. Basic Properties of Plasma-Neutral Coupling in the Solar Atmosphere

    Science.gov (United States)

    Goodman, Michael

    2015-04-01

    Plasma-neutral coupling (PNC) in the solar atmosphere concerns the effects of collisions between charged and neutral species’. It is most important in the chromosphere, which is the weakly ionized, strongly magnetized region between the weakly ionized, weakly magnetized photosphere and the strongly ionized, strongly magnetized corona. The charged species’ are mainly electrons, protons, and singly charged heavy ions. The neutral species’ are mainly hydrogen and helium. The resistivity due to PNC can be several orders of magnitude larger than the Spitzer resistivity. This enhanced resistivity is confined to the chromosphere, and provides a highly efficient dissipation mechanism unique to the chromosphere. PNC may play an important role in many processes such as heating and acceleration of plasma; wave generation, propagation, and dissipation; magnetic reconnection; maintaining the near force-free state of the corona; and limiting mass flux into the corona. It might play a major role in chromospheric heating, and be responsible for the existence of the chromosphere as a relatively thin layer of plasma that emits a net radiative flux 10-100 times greater than that of the overlying corona. The required heating rate might be generated by Pedersen current dissipation triggered by the rapid increase of magnetization with height in the lower chromosphere, where most of the net radiative flux is emitted. Relatively cool regions of the chromosphere might be regions of minimal Pedersen current dissipation due to smaller magnetic field strength or perpendicular current density. This talk will discuss PNC from an MHD point of view, and focus on the basic parameters that determine its effectiveness. These parameters are ionization fraction, magnetization, and the electric field that drives current perpendicular to the magnetic field. By influencing this current and the electric field that drives it, PNC directly influences the rate at which energy is exchanged between the

  7. Interaction of Desulfovibrio aespoeensis with plutonium

    International Nuclear Information System (INIS)

    Moll, H.; Merroun, M.; Selenska-Pobell, S.; Bernhard, G.

    2005-01-01

    Full text of publication follows: Microbes are widely distributed in nature and they can strongly influence the migration of actinides in the environment. Microorganisms in concentrations of 1 x 10 3 to 5 x 10 6 cells ml -1 were estimated by Pedersen et al. in the aquifer system of the Aespoe Hard Rock Laboratory (Aespoe HRL) in Sweden. The number of sulfate-reducing bacteria (SRB) was between 10 1 to 2 x 10 4 cells ml -1 . We investigated the interaction of the SRB Desulfovibrio aespoeensis, DSM 10631 T , with plutonium. The 242 Pu was provided as a mixture of ca. 46% Pu(VI) and ca. 34% Pu(IV)-polymer. Interactions between bacteria and plutonium in mixed oxidation states were not yet intensively investigated. In this study, accumulation experiments were performed in order to obtain information about the amount of the Pu bound by bacteria in dependence on the contact time and the [Pu] initial at pH 5. We used liquid-liquid-extractions and absorption spectroscopy to determine the Pu speciation. In agreement with the results obtained with U(VI) [2] and Np(V), we found a strong dependence of the amount of accumulated Pu with [Pu] initial . Based on our results and taking into consideration the findings of Panak et al. [3], we developed a model describing the interaction of Pu(VI) and Pu(IV)- polymers with D. aespoeensis. In a first step, the Pu(VI) and Pu(IV)-polymers are bound to the biomass. The Pu(VI) is reduced to Pu(V) due to the activity of the cells within the first 24 h of contact time. Most of the formed Pu(V) dissolves due to the weak complexing properties. The dissolved Pu(V) disproportionates to Pu(IV) and Pu(VI) which are then interacting with functional groups of the cell surface structure. Indications were found also for a penetration of Pu species inside the bacterial cells. [1] Pedersen, K.: Microbial processes in radioactive waste disposal. SKB Technical Report TR-00- 04 (2000). [2] Moll, H.; Merroun, M.; Stumpf, Th.; Geipel, G.; Selenska-Pobell, S

  8. Nonlocal linear theory of the gradient drift instability in the equatorial electrojet

    International Nuclear Information System (INIS)

    Ronchi, C.; Similon, P.L.; Sudan, R.N.

    1989-01-01

    The linear global eigenmodes of the gradient drift instability in the daytime equatorial electrojet are investigated. A main feature of the analysis is the inclusion of ion-neutral and electron-neutral collision frequencies dependent on altitude. It is found that the basic characteristics and localization of the unstable modes are determined mainly by the profiles of the Pedersen and Hall mobilities, which are derived from the Cowling conductivity model and experimental data. The equilibrium density profile is parabolic, which is fairly representative of the actual measurements. The unstable modes are sensitive not to the details of this profile, but only to the average value of the gradient. The results are obtained from a direct numerical integration of nonlocal linearized equations. They are further analyzed through an eikonal analysis, which provides both an interpretation of the transient modes observed by Fu et al. (1986) and some additional physics insight into the linear evolution of the global unstable modes. Finally, it is shown that the previously reported short-wavelength stabilization effect due to velocity shear may be overshadowed by the presence of regions in which the transient modes can develop into absolute instabilities. copyright American Geophysical Union 1989

  9. Genetic factors may play a prominent role in the development of coronary heart disease dependent on important environmental factors

    Science.gov (United States)

    Song, C; Chang, Z; Magnusson, P K E; Ingelsson, E; Pedersen, N L

    2014-01-01

    Astract Song C, Chang Z, Magnusson PKE, Ingelsson E, Pedersen NL (Karolinska Institutet, Stockholm; Uppsala University, Uppsala; Sweden). Genetic factors may play a prominent role in the developmentofcoronary heart diseasedependenton important environmental factors. J InternMed2014; 275: 631–639. Objective The aim of the study was to examine whether various lifestyle factors modify genetic influences on coronary heart disease (CHD). Design The effect of lifestyle factors [including smoking, sedentary lifestyle, alcohol intake and body mass index (BMI)] on risk of CHD was evaluated via Cox regression models in a twin study of gene–environment interaction. Using structure equation modelling, we estimated genetic variance of CHD dependent on lifestyle factors. Subjects In total, 51 065 same-sex twins from 25 715 twin pairs born before 1958 and registered in the Swedish Twin Registry were eligible for this study. During the 40-year follow-up, 7264 incident CHD events were recorded. Results Smoking, sedentary lifestyle and above average BMI were significantly associated with increased CHD incidence. The heritability of CHD decreased with increasing age, as well as with increasing levels of BMI, in both men and women. Conclusions The difference in the genetic component of CHD as a function of BMI suggests that genetic factors may play a more prominent role for disease development in the absence of important environmental factors. Increased knowledge of gene–environment interactions will be important for a full understanding of the aetiology of CHD. PMID:24330166

  10. Three-dimensional current flow and particle precipitation in a westward travelling surge (observed during the barium-GEOS rocket experiment)

    International Nuclear Information System (INIS)

    Opgenoorth, H.J.; Pellinen, R.J.; Baumjohann, W.; Nielsen, E.; Marklund, G.; Eliasson, L.

    1983-01-01

    During the Barium-GEOS rocket experiment on September 24, 1979 the passage of a westward travelling surge (WTS) was observed over Scandinavia. Extended instrument networks in that area, viz., the Scandinavian Magnetometer Array, the STARE radars, all-sky cameras, and riometers, allowed simultaneous observation of the two-dimensional character of magnetic and electric field disturbances and particle precipitation associated with the auroral feature. By combination of the different datasets and additional information from particle and electric field measurements aboard the Barium-GEOS rocket it was possible to derive the two-dimensional distribution of ionospheric electric fields and conductivities and to model the three-dimensional current flow in the vicinity of the westward travelling surge. The main feature of the resulting model current system is the presence of a localized upward field-aligned current directed out of the head of the surge and fed by a westward electrojet, which is composed of both Hall and Pedersen currents. Secondary ionospheric currents, e.g. a counterclockwise loop of mainly Hall currents around the leading edge of the surge, are found to be responsible for most of the transient effects observed by ground-based magnetometers as the WTS passed overhead. The most energetic particle precipitation as inferred from cosmic noise absorption measurements and triangulation of auroral arc altitudes is found to be confined to the leading part and central regions of the surge and to travel westward with the visual auroral form

  11. Alfven waves in the auroral ionosphere: A numerical model compared with measurements

    International Nuclear Information System (INIS)

    Knudsen, D.J.; Kelley, M.C.; Vickrey, J.F.

    1992-01-01

    The authors solve a linear numerical model of Alfven waves reflecting from the high-latitude ionosphere, both to better understanding the role of the ionosphere in the magnetosphere/ionosphere coupling process and to compare model results with in situ measurements. They use the model to compute the frequency-dependent amplitude and phase relations between the meridional electric and the zonal magnetic fields due to Alfven waves. These relations are compared with measurements taken by an auroral sounding rocket flow in the morningside oval and by the HILAT satellite traversing the oval at local noon. The sounding rocket's trajectory was mostly parallel to the auroral oval, and is measured enhanced fluctuating field energy in regions of electron precipitation. The rocket-measured phase data are in excellent agreement with the Alfven wave model, and the relation between the modeled and the measured by HILAT are related by the height-integrated Pedersen conductivity Σ p , indicating that the measured field fluctuations were due mainly to structured field-aligned current systems. A reason for the relative lack of Alfven wave energy in the HILAT measurements could be the fact that the satellite traveled mostly perpendicular to the oval and therefore quickly traversed narrow regions of electron precipitation and associated wave activity

  12. Confinement of pure electron plasmas in the Columbia Non-neutral Torus

    International Nuclear Information System (INIS)

    Berkery, John W.; Pedersen, Thomas Sunn; Kremer, Jason P.; Marksteiner, Quinn R.; Lefrancois, Remi G.; Hahn, Michael S.; Brenner, Paul W.

    2007-01-01

    The Columbia Non-neutral Torus (CNT) [T. S. Pedersen, J. P. Kremer, R. G. Lefrancois, Q. Marksteiner, N. Pomphrey, W. Reiersen, F. Dahlgreen, and X. Sarasola, Fusion Sci. Technol. 50, 372 (2006)] is a stellarator used to study non-neutral plasmas confined on magnetic surfaces. A detailed experimental study of confinement of pure electron plasmas in CNT is described here. Electrons are introduced into the magnetic surfaces by placing a biased thermionic emitter on the magnetic axis. As reported previously, the insulated rods holding this and other emitter filaments contribute to the radial transport by charging up negatively and creating ExB convective transport cells. A model for the rod-driven transport is presented and compared to the measured transport rates under a number of different conditions, finding good agreement. Neutrals also drive transport, and by varying the neutral pressure in the experiment, the effects of rod-driven and neutral-driven transport are separated. The neutral-driven electron loss rate scales linearly with neutral pressure. The neutral driven transport, presumably caused by electron-neutral collisions, is much greater than theoretical estimates for neoclassical diffusion in a classical stellarator with strong radial electric fields. In fact the confinement time is on the order of the electron-neutral collision time. Ion accumulation, electron attachment, and other effects are considered, but do not explain the observed transport rates

  13. Ion accumulation in an electron plasma confined on magnetic surfaces

    International Nuclear Information System (INIS)

    Berkery, John W.; Marksteiner, Quinn R.; Pedersen, Thomas Sunn; Kremer, Jason P.

    2007-01-01

    Accumulation of ions can alter and may destabilize the equilibrium of an electron plasma confined on magnetic surfaces. An analysis of ion sources and ion content in the Columbia Non-neutral Torus (CNT) [T.S. Pedersen, J.P. Kremer, R.G. Lefrancois, Q. Marksteiner, N. Pomphrey, W. Reiersen, F. Dahlgreen, and X. Sarasola, Fusion Sci. Technol. 50, 372 (2006)] is presented. In CNT ions are created preferentially at locations of high electron temperature, near the outer magnetic surfaces. A volumetric integral of n e ν iz gives an ion creation rate of 2.8x10 11 ions/s. This rate of accumulation would cause neutralization of a plasma with 10 11 electrons in about half a second. This is not observed experimentally, however, because currently in CNT ions are lost through recombination on insulated rods. From a steady-state balance between the calculated ion creation and loss rates, the equilibrium ion density in a 2x10 -8 Torr neutral pressure, 7.5x10 11 m -3 electron density plasma in CNT is calculated to be n i =6.2x10 9 m -3 , or 0.8%. The ion density is experimentally measured through the measurement of the ion saturation current on a large area probe to be about 6.0x10 9 m -3 for these plasmas, which is in good agreement with the predicted value

  14. Examining the Electric Fields of the Evening Equatorial Ionosphere When the Solar Terminator is Aligned and Not Aligned with the Magnetic Meridian

    Science.gov (United States)

    Eccles, J. V.

    2014-12-01

    The electric field structure of the equatorial ionosphere near sunset has implications on the development of plasma irregularities. The details of the development of the electric fields are examined using a global ionosphere-electrodynamics model. The results of simulations of simplified conditions show the influence of the arrangement of the solar terminator with the magnetic meridian. The relationships of the Curl-Free mechanism, the Hall Current Divergence mechanism, and the role of the Equatorial Electorjet region control the magnitude and timing of the Prereversal Enhancement of the zonal electric field as well as its altitude profile above the F region bottomside. Realistic conditions for 'equinox' and 'solstice' solar terminator arrangments are presented. The stability of the low-latitude ionosphere has a demonstrated relationship with the solar terminator alignment [Tsunoda, JGR, 1981]. The profile of the vertical and zonal electric field below the bottomside is then examined using the global model to explore the controlling elements of the electric field structure and the growth rates of the Rayleigh-Taylor instability and Collisional Shear instability.Tsunoda, R. T. (1985), Control of the seasonal and longitudinal occurrence of equatorial scintillations by the longitudinal gradient in integrated E region Pedersen conductivity, J. Geophys. Res., 90(A1),447-456, doi:10.1029/JA090iA01p00447.

  15. Effects of interplanetary magnetic field and magnetospheric substorm variations on the dayside aurora

    Science.gov (United States)

    Sandholt, P. E.; Egeland, A.; Lybekk, B.; Deehr, C. S.; Sivjee, G. G.; Romick, G. J.

    1983-11-01

    Photometric auroral observations and geomagnetic measurements obtained simultaneously on the dayside in Norway and the nightside in the USSR, Alaska, and Canada are combined with ISEE-1 and 3 data on the interplanetary magnetic field (IMF) to study the relative importance of substorm perturbations and IMF in determining dayside auroral (DA) motion. Ten events from December, 1978, and January and December, 1979, are characterized, the data are presented in tables, illustrated with charts and graphs, and summarized. The equatorward and poleward motion of the DA is correlated with the growth and decay of DP2-mode geomagnetic disturbances and changes in the north-south component of the IMF. Discrete DA forms appear in a region of sunward-convecting field lines. A detailed model of DA motion is developed which explains these phenomena as the result of a direct global response of the magnetospheric electromagnetic state to the solar-wind magnetic field. Using the model, the potential drop, Pedersen current, and Joule heat-dissipation rate of the polar-cap ionosphere are estimated as 125 kV, 800,000 A, and 100 GW, respectively.

  16. Sensitization of the nociceptive system in patients with low back pain and sickness absence: Disc degeneration disease or pain syndrome

    DEFF Research Database (Denmark)

    Jensen, Ole Kudsk; Nielsen, Claus Vinther; Stengaard-Pedersen, Kristian

    SENSITIZATION OF THE NOCICEPTIVE SYSTEM IN PATIENTS WITH LOW BACK PAIN AND SICKNESS ABSENCE O.K. Jensen1, C.V. Nielsen2, K. Stengaard-Pedersen3 1The Spine Center, Department of Internal Medicine, Region Hospital Silkeborg, 2Department of Clinical Social Medicine, University of Aarhus, and 3...... characterized by sensitization of the nociceptive system. Purpose: To assess sensitization of the nociceptive system in low back pain (LBP) patients by means of TP examination and measure of Pressure Pain Threshold (PPT) on the thumb nails. To search for associations between the number of TPs and structural...... = 1.35, p = 0.017) and mental distress (anxiety) in men (OR = 1.39, p = 0.003). After adjustment for age and sex, a positive association between LBP score and DDS was found only in patients with less than six TPs (OR = 1.21 (1.0-1.47), p = 0.043). Low PPT on the thumb nails was associated with DDS...

  17. Interaction between beam control and rf feedback loops for high Q cavities an heavy beam loading. Revision A

    International Nuclear Information System (INIS)

    Mestha, L.K.; Kwan, C.M.; Yeung, K.S.

    1994-04-01

    An open-loop state space model of all the major low-level rf feedback control loops is derived. The model has control and state variables for fast-cycling machines to apply modern multivariable feedback techniques. A condition is derived to know when exactly we can cross the boundaries between time-varying and time-invariant approaches for a fast-cycling machine like the Low Energy Booster (LEB). The conditions are dependent on the Q of the cavity and the rate at which the frequency changes with time. Apart from capturing the time-variant characteristics, the errors in the magnetic field are accounted in the model to study the effects on synchronization with the Medium Energy Booster (MEB). The control model is useful to study the effects on beam control due to heavy beam loading at high intensities, voltage transients just after injection especially due to time-varying voltages, instability thresholds created by the cavity tuning feedback system, cross coupling between feedback loops with and without direct rf feedback etc. As a special case we have shown that the model agrees with the well known Pedersen model derived for the CERN PS booster. As an application of the model we undertook a detailed study of the cross coupling between the loops by considering all of them at once for varying time, Q and beam intensities. A discussion of the method to identify the coupling is shown. At the end a summary of the identified loop interactions is presented

  18. Effects of a conducting E layer on classical F region cross-field plasma diffusion

    International Nuclear Information System (INIS)

    Vickrey, J.F.; Kelley, M.C.

    1982-01-01

    The rate of cross-field plasma diffusion in the F region ionosphere is significantly increased when the magnetic field lines thread a highly conducting E region below. This reduces the lifetime of small-scale F region electron density irregularities in the polar ionosphere where the presence of a highly conducting E region is comonplace. A simple mmodel is developed to describe the effects of a conducting E layer on classical F region plasma diffusion. In the absence of an E region, the difference in ion and electron diffusion rates leads to a charge separation and, hence, to an electrostatic field that retards ion diffusion. When the highly conducting magnetic field lines are tied to a conducting E region, however, electrons can flow along B to reduce the ambipolar diffusion electric field, and ions can proceed perpendicular to B at a rate approaching their own (higher) diffusion velocity. It is shown that the enhanced total diffusion rate that results depends strongly on the height of the F layer and on the ratio of the E to F region Pedersen conductivities

  19. Musikterapiuddannelsen 25 år - Festskrift

    DEFF Research Database (Denmark)

    musikterapeutisk hovedinstrument?  - ændrede studieordninger på musikterapiuddannelsen Lars Ole Bonde: Studieordningen af 2006 i praksis. Erfaringer fra det første år Carl Bergstrøm-Nielsen: En ny musikfaglighed Britta Kvist: Mit liv som UA'er i 24 år Niels Hannibal: Når teori og praksis lever side om side Tony...... Wigram: Doctoral Research School in Music Therapy, Aalborg University Lars Ole Bonde: Forskerskolen i musikterapi - en international succes Peder Kaj Pedersen: Musikterapeutiske forskningsstrategier. Profane replikker fra sidelinien Anne Steen Møller: "Musikterapeut? Hvor spændende! Hvad laver sådan én......?" Helga Pallesen: En ældre studerende på en ung uddannelse Lis Karlsen & Anne Eijgendaal: En historie om hvordan musikterapeuterne blev fagligt organiserede Hanne Mette Ridder: Hvor går kandidaterne hen, når de går ud?           Musiksatser af bl.a. Bo Hulgaard, Bjørn Veierskov Alexandersson, og Carl...

  20. A self-consistent derivation of ion drag and Joule heating for atmospheric dynamics in the thermosphere

    Directory of Open Access Journals (Sweden)

    X. Zhu

    2005-11-01

    Full Text Available The thermosphere is subject to additional electric and magnetic forces, not important in the middle and lower atmosphere, due to its partially ionized atmosphere. The effects of charged particles on the neutral atmospheric dynamics are often parameterized by ion drag in the momentum equations and Joule heating in the energy equation. Presented in this paper are a set of more accurate parameterizations for the ion drag and Joule heating for the neutral atmosphere that are functions of the difference between bulk ion velocity and neutral wind. The parameterized expressions also depend on the magnetic field, the Pedersen and Hall conductivities, and the ratio of the ion cyclotron frequency to the ion-neutral collision frequency. The formal relationship between the electromagnetic energy, atmospheric kinetic energy, and Joule heating is illustrated through the conversion terms between these three types of energy. It is shown that there will always be an accompanying conversion of kinetic energy into Joule heating when electromagnetic energy is generated through the dynamo mechanism of the atmospheric neutral wind. Likewise, electromagnetic energy cannot be fully converted into kinetic energy without producing Joule heating in the thermosphere.

  1. Selective Organic and Organometallic Reactions in Water-Soluble Host-Guest Supramolecular Systems

    Energy Technology Data Exchange (ETDEWEB)

    Pluth, Michael D.; Raymond, Kenneth N.; Bergman, Robert G.

    2008-02-16

    Inspired by the efficiency and selectivity of enzymes, synthetic chemists have designed and prepared a wide range of host molecules that can bind smaller molecules with their cavities; this area has become known as 'supramolecular' or 'host-guest' chemistry. Pioneered by Lehn, Cram, Pedersen, and Breslow, and followed up by a large number of more recent investigators, it has been found that the chemical environment in each assembly - defined by the size, shape, charge, and functional group availability - greatly influences the guest-binding characteristics of these compounds. In contrast to the large number of binding studies that have been carried out in this area, the exploration of chemistry - especially catalytic chemistry - that can take place inside supramolecular host cavities is still in its infancy. For example, until the work described here was carried out, very few examples of organometallic reactivity inside supramolecular hosts were known, especially in water solution. For that reason, our group and the group directed by Kenneth Raymond decided to take advantage of our complementary expertise and attempt to carry out metal-mediated C-H bond activation reactions in water-soluble supramolecular systems. This article begins by providing background from the Raymond group in supramolecular coordination chemistry and the Bergman group in C-H bond activation. It goes on to report the results of our combined efforts in supramolecular C-H activation reactions, followed by extensions of this work into a wider range of intracavity transformations.

  2. Distinguishing Alfven waves from quasi-static field structures associated with the discrete aurora: Sounding rocket and HILAT satellite measurements

    International Nuclear Information System (INIS)

    Knudsen, D.J.; Kelley, M.C.; Earle, G.D.; Vickrey, J.F.; Boehm, M.

    1990-01-01

    The authors present and analyze sounding rocket and HILAT satellite measurements of the low frequency ( 0 in the auroral oval. By examining the time-domain field data it is often difficult to distinguish temporal fluctuations from static structures which are Doppler shifted to a non-zero frequency in the spacecraft frame. However, they show that such a distinction can be made by constructing the impedance function Z(f). Using Z(f) they find agreement with the static field interpretation below about 0.1 Hz in the spacecraft frame, i.e. Z(f) = Σ p -1 where Σ p is the height-integrated Pedersen conductivity of the ionosphere. About 0.1 Hz the authors find Z(f) > Σ p -1 , which they argue to be due to the presence of Alfven waves incident from the magnetosphere and reflecting from the lower ionosphere, forming a standing wave pattern. These waves may represent an electromagnetic coupling mechanism between the auroral acceleration region and the ionosphere

  3. Persistência de plantas medicinais em sistemas agroflorestais no município de São Bento do Sul, SC, Brasil

    Directory of Open Access Journals (Sweden)

    A.L. Hanisch

    2013-01-01

    Full Text Available No final da década de 90, a comunidade de Rio Natal, no município de São Bento do Sul, SC, passou a fazer parte de uma Área de Preservação Ambiental e desde então, muitas áreas de cultivo, paulatinamente, estão retomando o processo de formação florestal. Neste cenário, foi sugerido pela comunidade, a possibilidade de cultivo de plantas medicinais adaptadas às condições de sombreamento. Em atendimento a essa demanda foi realizada uma pesquisa participativa na comunidade, de 2005 a 2008, onde foram avaliadas 14 espécies de plantas medicinais com potencial de mercado, cultivadas em áreas sombreadas, em três propriedades familiares. Foram avaliados: taxa de sobrevivência das espécies, incidência de doenças e pragas, teor de massa seca e altura das plantas. Apresentaram persistência ao cultivo em áreas sombreadas as espécies: Curcuma longa L. (açafrão-da-índia; Arctium lappa L. (bardana; Pfaffia glomerata (Spreng Pedersen (fáfia ou ginseng-brasileiro; Mikania glomerata Sprengel (guaco; Alternanthera brasiliana L. Kuntze (penicilina; Pogostemon cablin (Blanco Benth (patchuli e Maytenus ilicifolia Mart. Ex Reissek (espinheira-santa.

  4. Killing–Yano tensor and supersymmetry of the self-dual Plebański–Demiański solution

    International Nuclear Information System (INIS)

    Nozawa, Masato; Houri, Tsuyoshi

    2016-01-01

    We explore various aspects of the self-dual Plebański–Demiański (PD) family in the Euclidean Einstein–Maxwell-Λ system. The Killing–Yano tensor which was recently found by Yasui and one of the present authors allows us to prove that the self-dual PD metric can be brought into the self-dual Carter metric by an orientation-reversing coordinate transformation. We show that the self-dual PD solution admits two independent Killing spinors in the framework of N = 2 minimal gauged supergravity, whereas the non-self-dual solution admits only a single Killing spinor. This can be demonstrated by casting the self-dual PD metric into two distinct Przanowski–Tod forms. As a by-product, a new example of the three-dimensional Einstein–Weyl space is presented. We also prove that the self-dual PD metric falls into two different Calderbank–Pedersen families, which are determined by a single function subjected to a linear equation on the two-dimensional hyperbolic space. Furthermore, we consider the hyper-Kähler case for which the metric falls into the Gibbons–Hawking class. We find that the condition for the nonexistence of the Dirac–Misner string enforces the solution with a nonvanishing acceleration parameter to the Eguchi–Hanson space. (paper)

  5. Nucleus-size pinning for determination of nucleation free-energy barriers and nucleus geometry

    Science.gov (United States)

    Sharma, Abhishek K.; Escobedo, Fernando A.

    2018-05-01

    Classical Nucleation Theory (CNT) has recently been used in conjunction with a seeding approach to simulate nucleation phenomena at small-to-moderate supersaturation conditions when large free-energy barriers ensue. In this study, the conventional seeding approach [J. R. Espinosa et al., J. Chem. Phys. 144, 034501 (2016)] is improved by a novel, more robust method to estimate nucleation barriers. Inspired by the interfacial pinning approach [U. R. Pedersen, J. Chem. Phys. 139, 104102 (2013)] used before to determine conditions where two phases coexist, the seed of the incipient phase is pinned to a preselected size to iteratively drive the system toward the conditions where the seed becomes a critical nucleus. The proposed technique is first validated by estimating the critical nucleation conditions for the disorder-to-order transition in hard spheres and then applied to simulate and characterize the highly non-trivial (prolate) morphology of the critical crystal nucleus in hard gyrobifastigia. A generalization of CNT is used to account for nucleus asphericity and predict nucleation free-energy barriers for gyrobifastigia. These predictions of nuclei shape and barriers are validated by independent umbrella sampling calculations.

  6. Antileishmanial Activity of Medicinal Plants Used in Endemic Areas in Northeastern Brazil

    Directory of Open Access Journals (Sweden)

    Aline Cavalcanti De Queiroz

    2014-01-01

    Full Text Available This study investigates the leishmanicidal activity of five species of plants used in folk medicine in endemic areas of the state of Alagoas, Brazil. Data were collected in the cities of Colonia Leopoldina, Novo Lino, and União dos Palmares, Alagoas state, from patients with cutaneous leishmaniasis (Leishmania amazonensis who use medicinal plants to treat this disease. Plants extracts were tested at a concentration of 1–100 μg/mL in all experiments, except in an assay to evaluate activity against amastigotes, when 10 μg/mL was used. All plants extracts did not show deleterious activity to the host cell evidenced by LDH assay at 100, 10, and 1 μg/mL after 48 h of incubation. The plants extracts Hyptis pectinata (L. Poit, Aloe vera L., Ruta graveolens L., Pfaffia glomerata (Spreng. Pedersen, and Chenopodium ambrosioides L. exhibited direct activity against extracellular forms at 100 μg/mL; these extracts inhibited growth by 81.9%, 82.9%, 74.4%, 88.7%, and 87.4%, respectively, when compared with promastigotes. The plants extracts H. pectinata, A. vera, and R. graveolens also significantly diminished the number of amastigotes at 10 μg/mL, inhibiting growth by 85.0%, 40.4%, 94.2%, and 97.4%, respectively, when compared with control. Based on these data, we conclude that the five plants exhibited considerable leishmanicidal activity.

  7. Effect modification, interaction and mediation: an overview of theoretical insights for clinical investigators

    Directory of Open Access Journals (Sweden)

    Corraini P

    2017-06-01

    Full Text Available Priscila Corraini,1 Morten Olsen,1 Lars Pedersen,1 Olaf M Dekkers,1,2 Jan P Vandenbroucke1–3 1Department of Clinical Epidemiology, Institute of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark; 2Leiden University Medical Center, Leiden, the Netherlands; 3Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK Abstract: We revisited the three interrelated epidemiological concepts of effect modification, interaction and mediation for clinical investigators and examined their applicability when using research databases. The standard methods that are available to assess interaction, effect modification and mediation are explained and exemplified. For each concept, we first give a simple “best-case” example from a randomized controlled trial, followed by a structurally similar example from an observational study using research databases. Our explanation of the examples is based on recent theoretical developments and insights in the context of large health care databases. Terminology is sometimes ambiguous for what constitutes effect modification and interaction. The strong assumptions underlying the assessment of interaction, and particularly mediation, require clinicians and epidemiologists to take extra care when conducting observational studies in the context of health care databases. These strong assumptions may limit the applicability of interaction and mediation assessments, at least until the biases and limitations of these assessments when using large research databases are clarified. Keywords: methods, epidemiology, effect modifiers, stratified analyses, health care administrative claims

  8. Electrodynamics of the magnetosphere-ionosphere coupling in the nightside subauroral zone

    International Nuclear Information System (INIS)

    Streltsov, A.V.; Foster, J.C.

    2004-01-01

    Results from a numerical study of the oscillations of the electric field measured by the Millstone Hill incoherent scatter radar in the E-layer of the nightside subauroral ionosphere during the geomagnetic storm of May 25, 2000 are presented. The frequencies of these oscillations correspond to the discrete frequencies of geomagnetic pulsations usually attributed to the field line resonances or global cavity modes at a high-latitude auroral zone, but they are well below the fundamental eigenfrequency of the subauroral magnetosphere. It is shown that these oscillations can be interpreted as an ionospheric footprint of the surface Alfven waves generated at the equatorial magnetosphere on a steep transverse gradient in the background plasma density associated with the inner edge of the plasmapause developed during strong geomagnetic storms/substorms. This density gradient together with the ionospheric Pedersen conductivity defines the location and amplitude of the electric field in the E-layer: the amplitude of the field is proportional to the amplitude of the density inhomogeneity and inversely proportional to its scale-size and the ionospheric conductivity. Interaction of the large amplitude perpendicular electric field with the low-conducting ionosphere can cause the ionospheric feedback instability, which leads to the formation of small-scale, intense structures in the electric field and the parallel current density in the subauroral magnetosphere

  9. Two-dimensional Radiative Magnetohydrodynamic Simulations of Partial Ionization in the Chromosphere. II. Dynamics and Energetics of the Low Solar Atmosphere

    Energy Technology Data Exchange (ETDEWEB)

    Martínez-Sykora, Juan [Bay Area Environmental Research Institute, Petaluma, CA 94952 (United States); Pontieu, Bart De; Hansteen, Viggo H. [Lockheed Martin Solar and Astrophysics Laboratory, Palo Alto, CA 94304 (United States); Carlsson, Mats; Gudiksen, Boris V. [Institute of Theoretical Astrophysics, University of Oslo, P.O. Box 1029 Blindern, NO-0315 Oslo (Norway); Nóbrega-Siverio, Daniel, E-mail: juanms@lmsal.com [Instituto de Astrofísica de Canarias, E-38200 La Laguna (Tenerife) (Spain)

    2017-09-20

    We investigate the effects of interactions between ions and neutrals on the chromosphere and overlying corona using 2.5D radiative MHD simulations with the Bifrost code. We have extended the code capabilities implementing ion–neutral interaction effects using the generalized Ohm’s law, i.e., we include the Hall term and the ambipolar diffusion (Pedersen dissipation) in the induction equation. Our models span from the upper convection zone to the corona, with the photosphere, chromosphere, and transition region partially ionized. Our simulations reveal that the interactions between ionized particles and neutral particles have important consequences for the magnetothermodynamics of these modeled layers: (1) ambipolar diffusion increases the temperature in the chromosphere; (2) sporadically the horizontal magnetic field in the photosphere is diffused into the chromosphere, due to the large ambipolar diffusion; (3) ambipolar diffusion concentrates electrical currents, leading to more violent jets and reconnection processes, resulting in (3a) the formation of longer and faster spicules, (3b) heating of plasma during the spicule evolution, and (3c) decoupling of the plasma and magnetic field in spicules. Our results indicate that ambipolar diffusion is a critical ingredient for understanding the magnetothermodynamic properties in the chromosphere and transition region. The numerical simulations have been made publicly available, similar to previous Bifrost simulations. This will allow the community to study realistic numerical simulations with a wider range of magnetic field configurations and physics modules than previously possible.

  10. Magnetic-field-aligned characteristics of plasma bubbles in the nighttime equatorial ionosphere

    International Nuclear Information System (INIS)

    Tsunoda, R.T.

    1980-01-01

    Measurements of both incoherent-scatter (IS) and backscatter from field-aligned irregularities (FAI) were made in 1978 with ALTAIR, a fully-steerable high-power radar, to investigate the magnetic-field-aligned characteristics of equatorial plasma bubbles. By operating the radar in a latitude-scan IS mode it was possible to map the location and percentage depletion of plasma bubbles as a function of altitude. By showing that backscatter from FAI is spatially collocated with the upper wall of plasma bubbles it was possible to use the spatial displacement of a field aligned backscatter region to estimate the upward bubble velocity. Besides showing that plasma bubbles are indeed aligned along magnetic field lines, this data set is used to show that a plasma bubble with a percentage depletion of as much as 90% does not have as large an upward velocity as predicted by two-dimensional models. Instead, the inferred bubble velocity is shown to be in better agreement with the bubble velocity predicted by theoretical models using flux-integrated values of electron density and Pedersen conductivity. The need to use flux-tube-integrated values when comparing theory and observation is further stressed by the presence of a non-uniform latitudinal distribution of electron density (i.e. the equatorial anomaly) that was found in the latitude-scan data. (author)

  11. Evidence and effects of a wave-driven nonlinear current in the equatorial electrojet

    Directory of Open Access Journals (Sweden)

    M. Oppenheim

    1997-07-01

    Full Text Available Ionospheric two-stream waves and gradient-drift waves nonlinearly drive a large-scale (D.C. current in the E-region ionosphere. This current flows parallel to, and with a comparable magnitude to, the fundamental Pedersen current. Evidence for the existence and magnitude of wave-driven currents derives from a theoretical understanding of E-region waves, supported by a series of nonlinear 2D simulations of two-stream waves and by data collected by rocket instruments in the equatorial electrojet. Wave-driven currents will modify the large-scale dynamics of the equatorial electrojet during highly active periods. A simple model shows how a wave-driven current appreciably reduces the horizontally flowing electron current of the electrojet. This reduction may account for the observation that type-I radar echoes almost always have a Doppler velocity close to the acoustic speed, and also for the rocket observation that electrojet regions containing gradient-drift waves do not appear also to contain horizontally propagating two-stream waves. Additionally, a simple model of a gradient-drift instability shows that wave-driven currents can cause nonsinusoidal electric fields similar to those measured in situ.

  12. Double-exponential decay of orientational correlations in semiflexible polyelectrolytes.

    Science.gov (United States)

    Bačová, P; Košovan, P; Uhlík, F; Kuldová, J; Limpouchová, Z; Procházka, K

    2012-06-01

    In this paper we revisited the problem of persistence length of polyelectrolytes. We performed a series of Molecular Dynamics simulations using the Debye-Hückel approximation for electrostatics to test several equations which go beyond the classical description of Odijk, Skolnick and Fixman (OSF). The data confirm earlier observations that in the limit of large contour separations the decay of orientational correlations can be described by a single-exponential function and the decay length can be described by the OSF relation. However, at short countour separations the behaviour is more complex. Recent equations which introduce more complicated expressions and an additional length scale could describe the results very well on both the short and the long length scale. The equation of Manghi and Netz when used without adjustable parameters could capture the qualitative trend but deviated in a quantitative comparison. Better quantitative agreement within the estimated error could be obtained using three equations with one adjustable parameter: 1) the equation of Manghi and Netz; 2) the equation proposed by us in this paper; 3) the equation proposed by Cannavacciuolo and Pedersen. Two characteristic length scales can be identified in the data: the intrinsic or bare persistence length and the electrostatic persistence length. All three equations use a single parameter to describe a smooth crossover from the short-range behaviour dominated by the intrinsic stiffness of the chain to the long-range OSF-like behaviour.

  13. Numerical investigation of three-dimensional single-species plasma equilibria on magnetic surfaces

    International Nuclear Information System (INIS)

    Lefrancois, Remi G.; Pedersen, Thomas Sunn; Boozer, Allen H.; Kremer, Jason P.

    2005-01-01

    Presented for the first time are numerical solutions to the three-dimensional nonlinear equilibrium equation for single-species plasmas confined on magnetic surfaces and surrounded by an equipotential boundary. The major-radial shift of such plasmas is found to be outward, qualitatively similar to the Shafranov shift of quasineutral plasmas confined on magnetic surfaces. However, this is the opposite of what occurs in the pure toroidal field equilibria of non-neutral plasmas (i.e., in the absence of magnetic surfaces). The effect of varying the number of Debye lengths in the plasma for the three-dimensional (3D) model is in agreement with previous 2D calculations: the potential varies significantly on magnetic surfaces for plasmas with few Debye lengths (a d ), and tends to be constant on surfaces when many Debye lengths are present (a > or approx. 10λ d ). For the case of a conducting boundary that does not conform to the outer magnetic surface, the plasma is shifted towards the conductor and the potential varies significantly on magnetic surfaces near the plasma edge. Debye shielding effects are clearly demonstrated when a nonuniform bias is applied to the boundary. Computed equilibrium profiles are presented for the Columbia Non-Neutral Torus [T. S. Pedersen, A. H. Boozer, J. P. Kermer, R. Lefrancois, F. Dahlgren, N. Pomphrey, W. Reiersen, and W. Dorland, Fusion Sci. Technol. 46, 200 (2004)], a stellarator designed to confine non-neutral plasmas

  14. Electromagnetic energy deposition rate in the polar upper thermosphere derived from the EISCAT Svalbard radar and CUTLASS Finland radar observations

    Directory of Open Access Journals (Sweden)

    H. Fujiwara

    2007-11-01

    Full Text Available From simultaneous observations of the European incoherent scatter Svalbard radar (ESR and the Cooperative UK Twin Located Auroral Sounding System (CUTLASS Finland radar on 9 March 1999, we have derived the height distributions of the thermospheric heating rate at the F region height in association with electromagnetic energy inputs into the dayside polar cap/cusp region. The ESR and CUTLASS radar observations provide the ionospheric parameters with fine time-resolutions of a few minutes. Although the geomagnetic activity was rather moderate (Kp=3+~4, the electric field obtained from the ESR data sometimes shows values exceeding 40 mV/m. The estimated passive energy deposition rates are also larger than 150 W/kg in the upper thermosphere over the ESR site during the period of the enhanced electric field. In addition, enhancements of the Pedersen conductivity also contribute to heating the upper thermosphere, while there is only a small contribution for thermospheric heating from the direct particle heating due to soft particle precipitation in the dayside polar cap/cusp region. In the same period, the CUTLASS observations of the ion drift show the signature of poleward moving pulsed ionospheric flows with a recurrence rate of about 10–20 min. The estimated electromagnetic energy deposition rate shows the existence of the strong heat source in the dayside polar cap/cusp region of the upper thermosphere in association with the dayside magnetospheric phenomena of reconnections and flux transfer events.

  15. Dynamics of the low latitude thermosphere and ionosphere

    International Nuclear Information System (INIS)

    Burnside, R.G.

    1984-01-01

    Nighttime thermospheric neutral wind velocities were determined at Arecibo, Puerto Rico, by using a Fabry-Perot interferometer, which measures the Doppler shift of the O( 1 D) airglow emission. In summer, the winds are observed to flow toward the southeast between sunset and midnight. After midnight in summer, the meridional component of the wind usually slackens, while the zonal component may reverse. By contrast, in winter, the meridional wind is often small, and the predominant flow is eastward throughout the night. Vertical winds are inferred from the divergence of the horizontal flow. A maximum downward flow of about 5 m sπ 1 is observed near midnight in summer. Incoherent scatter radar measurements were used to calculate the O + diffusion velocity and infer the vertical profile of the meridional wind. Horizontal temperature gradients and ion-drag forces were evaluated from radar measurements. It is concluded that it may sometimes be necesary to include viscous forces to balance the meridional equation of motion for the neutral gas. Electrical conductivities of the E and F layers of the nighttime ionosphere were determined. The F layer Pedersen conductivity at the magnetically conjugate point was evaluated using ionosonde data. The F layer dynamo mechanism was found to be the source of most of the nighttime electric fields observed at Arecibo

  16. Modeling ionospheric pre-reversal enhancement and plasma bubble growth rate using data assimilation

    Science.gov (United States)

    Rajesh, P. K.; Lin, C. C. H.; Chen, C. H.; Matsuo, T.

    2017-12-01

    We report that assimilating total electron content (TEC) into a coupled thermosphere-ionosphere model by using the ensemble Kalman filter results in improved specification and forecast of eastward pre-reversal enhancement (PRE) electric field (E-field). Through data assimilation, the ionospheric plasma density, thermospheric winds, temperature and compositions are adjusted simultaneously. The improvement of dusk-side PRE E-field over the prior state is achieved primarily by intensification of eastward neutral wind. The improved E-field promotes a stronger plasma fountain and deepens the equatorial trough. As a result, the horizontal gradients of Pedersen conductivity and eastward wind are increased due to greater zonal electron density gradient and smaller ion drag at dusk, respectively. Such modifications provide preferable conditions and obtain a strengthened PRE magnitude closer to the observation. The adjustment of PRE E-field is enabled through self-consistent thermosphere and ionosphere coupling processes captured in the model. The assimilative outputs are further utilized to calculate the flux tube integrated Rayleigh-Taylor instability growth rate during March 2015 for investigation of global plasma bubble occurrence. Significant improvements in the calculated growth rates could be achieved because of the improved update of zonal electric field in the data assimilation forecast. The results suggest that realistic estimate or prediction of plasma bubble occurrence could be feasible by taking advantage of the data assimilation approach adopted in this work.

  17. Armenian Demons Called Kaj: Image and Name

    Directory of Open Access Journals (Sweden)

    Armen Y. Petrosyan

    2018-03-01

    Full Text Available The article provides a study of Armenian demons, the kajs, and their superior deity — the dragonslayer Vahagn, in the historical-etymological and ethno-cultural perspective. Specific features of kajs and their leader as imagined by ancient people are identifi ed: they resemble vishap-dragons and devs, live in the mountains and have temples there, make war, hunt, steal wheat and wine from people, love music, arrange weddings, drive people crazy, braid horsehair, and so on. Clear linkages are drawn between Armenian kajs and their leader with the mythological characters of Indo-European (Iranian, Indian traditions. In Armenian, the fi rst meaning of k‘aǰ is ‘good, select; of fi ne / better quality’. This is exactly how some Armenian spirits, including kajs, are often referred to — as “good” — mezane laver, mezne ałekner ‘better than us,’ ałek manuk ‘good youngster / warrior’. This is also true to some other traditions: the Persian az mā behtarān, German Gude (cf. also the names of Indian vasu and sādhya. The article develops the etymology of the name k‘aǰ (a corrected version of that proposed by H. Pedersen in 1906: *swo-sHdhyo- — ‘self / own + right / righteous,’ i.e. ‘good’. This image passed into the Georgian and Ossetian traditions (Georgian kajs, Ossetian kadzi.

  18. COMPOSITION OF STAFF REVIEW ADVISORY BODIES - 2001

    CERN Multimedia

    Seamus Hegarty / HR; Tel. 74128

    2001-01-01

    For the present staff review, the advisory bodies set up to prepare recommendations are composed as follows : Senior Staff Advancement Committee (SSAC) David O. Williams/it (Convener) Cristoforo Benvenuti/est David Plane/ep Technical Engineers & Administrative Careers Committee (TEACC) Sverre Jarp/it (Chairman) Flemming Pedersen/ps Robin Lauckner/sl Christian Roche/ett Lars Leistam/est Dietrich Schinzel/ep Long-term contract Boards (LTCBs) LTCB 1 (Categories 2 & 5a) Tiziano Camporesi/ep [Convener] - Florence Ranjard/ep [Alternate] Jacques Gruber/ps - Peter Sievers/lhc [Alternate] Thomas Pettersson/est - Michel Mayoud/est [Alternate] Sue Foffano/as - Thierry Lagrange/spl [Alternate] Werner Zapf/hr (Secretary) LTCB 2 (Categories 3, 4, 5b & 5c) Véronique Paris/sl [Convener] - Fabien Perriollat/ps [Alternate] Mats Wilhelmsson/st - Véronique Fassnacht/tis [Alternate] Lucie Linssen/ep - Alfredo Placci/ep [Alternate] Patrick Geeraert/fi - John Cuthb...

  19. Electromagnetic energy deposition rate in the polar upper thermosphere derived from the EISCAT Svalbard radar and CUTLASS Finland radar observations

    Directory of Open Access Journals (Sweden)

    H. Fujiwara

    2007-11-01

    Full Text Available From simultaneous observations of the European incoherent scatter Svalbard radar (ESR and the Cooperative UK Twin Located Auroral Sounding System (CUTLASS Finland radar on 9 March 1999, we have derived the height distributions of the thermospheric heating rate at the F region height in association with electromagnetic energy inputs into the dayside polar cap/cusp region. The ESR and CUTLASS radar observations provide the ionospheric parameters with fine time-resolutions of a few minutes. Although the geomagnetic activity was rather moderate (Kp=3+~4, the electric field obtained from the ESR data sometimes shows values exceeding 40 mV/m. The estimated passive energy deposition rates are also larger than 150 W/kg in the upper thermosphere over the ESR site during the period of the enhanced electric field. In addition, enhancements of the Pedersen conductivity also contribute to heating the upper thermosphere, while there is only a small contribution for thermospheric heating from the direct particle heating due to soft particle precipitation in the dayside polar cap/cusp region. In the same period, the CUTLASS observations of the ion drift show the signature of poleward moving pulsed ionospheric flows with a recurrence rate of about 10–20 min. The estimated electromagnetic energy deposition rate shows the existence of the strong heat source in the dayside polar cap/cusp region of the upper thermosphere in association with the dayside magnetospheric phenomena of reconnections and flux transfer events.

  20. Biodegradable bags for the production of plant seedlings

    Directory of Open Access Journals (Sweden)

    Ana Paula Bilck

    2014-10-01

    Full Text Available The production of plant seedlings has traditionally used polyethylene bags, which are thrown out in the soil or burned after transplant because the large amount of organic material attached to the bags makes recycling difficult. Additionally, when a seedling is taken from the bag for transplant, there is the risk of root damage, which compromises the plant’s development. In this study, we developed biodegradable bags to be used in seedling production, and we verify their influence on the development of Brazilian ginseng (Pfaffia glomerata (Spreng Pedersen, when the plant is planted without being removed from the bag. Both black and white biodegradable bags remained intact throughout the seedling production period (60 days. After being transplanted into containers (240 days, they were completely biodegraded, and there was no significant difference between the dry mass of these plants and that of plants that were transplanted without the bags. The plants that were cultivated without being removed from the polyethylene bags had root development difficulties, and the wrapping showed no signs of degradation. The use of biodegradable films is an alternative for the production of bags for seedlings, as these can then be transplanted directly into the soil without removing the bag, reducing the risk of damage to the roots during the moment of transplant.

  1. An Ionosphere/Magnetosphere Coupling Current System Located in the Gap Between Saturn and its Rings

    Science.gov (United States)

    Khurana, K. K.; Dougherty, M. K.; Cao, H.; Hunt, G. J.; Provan, G.

    2017-12-01

    The Grand Finale Orbits of the Cassini spacecraft traversed through Saturn's D ring and brought the spacecraft to within 3000 km of Saturn's cloud tops. The closest approaches (CA) were near the equatorial plane of Saturn and were distributed narrowly around the local noon. The difference field (observations - internal field - magnetospheric ring current field) obtained from the Grand Finale orbits show persistent residual fields centered around the CA which diminish at higher latitudes on field lines that connect to the ring. Modeling of this perturbation in terms of internal harmonics shows that the perturbation is not of internal origin but is produced by external currents that couple the ionosphere to the magnetosphere. The sense of the current system suggests that the southern feet of the field lines in the ionosphere lead their northern footprints. We show that the observed field perturbations are consistent with a meridional Pedersen current whose strength is 1 MA/radian, i.e. comparable in strength to the Planetary-period-oscillation related current systems observed in the auroral zone. We show that the implied Lorentz force in the ionosphere extracts momentum from the faster moving southern ionosphere and passes it on to the northern ionosphere. We discuss several ideas for generating this current system. In particular, we highlight a mechanism that involves shears in the neutral winds in the thermospheric region to generate the observed magnetic field.

  2. Incidence of trismus in transalveolar extraction of lower third molar

    Directory of Open Access Journals (Sweden)

    Gowri Balakrishnan

    2017-01-01

    Full Text Available Background: Conventional mandibular third molar removal produces tissue trauma that induces an inflammatory reaction, leading to postoperative sequelae, the most common ones being trismus which influences the patient's quality of life in the postoperative period. Identifying the factors determining trismus after mandibular third molar extraction helps us to evaluate and correlate the incidence of trismus with morphological and surgical factors that are associated with its incidence in the postoperative period. Methodology: Patients referred to our institution for surgical removal of their impacted lower third molar between November 2014 and February 2015 were the participants of the study. Type of impaction, indication, and level of difficulty based on Pedersen criteria were obtained. Postoperative pain, swelling, and mouth opening (MO limitations were evaluated at postoperative day (POD 0, POD1, POD3, POD5, and POD7 and were analyzed. P < 0.05 was considered statistically significant. Result and Conclusion: In this study, out of fifty patients, only nine patients had experienced limited MO during postoperative period when the duration of procedure exceeded 30 min. However, it occurred as cumulative of pericoronitis and tooth sectioning done. The postoperative trismus was more significant in disto-angular impaction (P < 0.05 due to postoperative sequelae, swelling and pain.

  3. Hvad kan du tilbyde mig som muslim, præst?

    DEFF Research Database (Denmark)

    Skovsgaard, Steen

    2005-01-01

    . islam og kristendom var jeg i 1995 inviteret til et møde med en stor gruppe muslimer i Gellerup. Det var et debatmøde om islam og kristendom, hvor skoleleder og imam Abdul Wahid Pedersen og jeg skulle komme med oplæg og debattere. Og så kunne der efterfølgende stilles spørgsmål fra salen. Det var hér...... andre mennesker, eller om Gud elsker dig og vil ha’ noget med dig at gøre, den dag må du love mig at komme tilbage. For så har jeg noget at tilbyde dig. Indtil da må du nøjes med islam!” Et sådant svar ville ganske vist ha’ været længere, men der ville også ha’ været mere for den unge muslim at tænke på...... og overkommelige krav, som stilles dig i islam. Selv her har du svigtet og er skyldig! Skyldig til dom og til straf!”. Og hvis så muslimen skulle finde på at sige, at han da bestemt har opfyldt Guds vilje iflg. islam, så kan vi jo passende fortælle ham, at de krav som stilles i islam kun er en bleg...

  4. The soluble extracellular domain of E-cadherin interferes with EPEC adherence via interaction with the Tir:intimin complex.

    Science.gov (United States)

    Login, Frédéric H; Jensen, Helene H; Pedersen, Gitte A; Amieva, Manuel R; Nejsum, Lene N

    2018-06-19

    Enteropathogenic Escherichia coli (EPEC) causes watery diarrhea when colonizing the surface of enterocytes. The translocated intimin receptor (Tir):intimin receptor complex facilitates tight adherence to epithelial cells and formation of actin pedestals beneath EPEC. We found that the host cell adherens junction protein E-cadherin (Ecad) was recruited to EPEC microcolonies. Live-cell and confocal imaging revealed that Ecad recruitment depends on, and occurs after, formation of the Tir:intimin complex. Combinatorial binding experiments using wild-type EPEC, isogenic mutants lacking Tir or intimin, and E. coli expressing intimin showed that the extracellular domain of Ecad binds the bacterial surface in a Tir:intimin-dependent manner. Finally, addition of the soluble extracellular domain of Ecad to the infection medium or depletion of Ecad extracellular domain from the cell surface reduced EPEC adhesion to host cells. Thus, the soluble extracellular domain of Ecad may be used in the design of intervention strategies targeting EPEC adherence to host cells.-Login, F. H., Jensen, H. H., Pedersen, G. A., Amieva, M. R., Nejsum, L. N. The soluble extracellular domain of E-cadherin interferes with EPEC adherence via interaction with the Tir:intimin complex.

  5. Fast magnetic field penetration into an intense neutralized ion beam

    International Nuclear Information System (INIS)

    Armale, R.

    1992-06-01

    Experiments involving propagation of neutralized ion beams across a magnetic field indicate a magnetic field penetration time determined by the Hall resistivity rather than the Spitzer or Pedersen resistivity. In magnetohydrodynamics the Hall current is negligible because electrons and ions drift together in response to an electric field perpendicular to the magnetic field. For a propagating neutralized ion beam, the ion orbits are completely different from the electron orbits and the Hall current must be considered. There would be no effect unless there is a component of magnetic field normal to the surface which would usually be absent for a good conductor. It is necessary to consider electron inertia and the consequent penetration of the normal component to a depth c/ω p . In addition it is essential to consider a component of magnetic field parallel to the velocity of the beam which may be initially absent, but is generated by the Hall effect. The penetration time is determined by whistler waves rather than diffusion

  6. Auroral and magnetic variations in the polar cusp and cleft. Signatures of magnetopause boundary layer dynamics

    International Nuclear Information System (INIS)

    Sandholt, P.E.; Egeland, A.

    1987-10-01

    By combining continous ground-based observations of polar cleft/cusp auroras and local magnetic variations with electromagnetic parameters obtained from satellites in polar orbit (low-altitude cleft/cusp) and in the magnetosheath/interplanetary space, different electrodynamic processes in the polar cleft/cusp have been investigated. One of the more controversial questions in this field is related to the observed shifts in latitude of cleft/cusp auroras and the relationships with the interplanetary magnetic field (IMF) orientation, local magnetic disturbances (DP2 and DPY modes) and magnetospheric substorms. A new approach which may contribute to clarifying these complicated relationships, simultaneous groundbased observations of the midday and evening-midnight sectors of the auroral oval, is illustrated. A related topic is the spatial relationship between the cleft/cusp auroras and the ionospheric convection currents. A characteristic feature of the polar cusp and cleft regions during negative IMF B z is repeated occurrence of certain short-lived auroral structures moving in accordance with the local convection pattern. Satellite measurements of particle precipitation, magnetic field and ion drift components permit detailed investigations of the electrodynamics of these cusp/cleft structures. Information on electric field components, Birkeland currents, Poynting flux, height-integrated Pedersen conductivity and Joule heat dissipation rate has been derived. These observations are discussed in relation to existing models of temporal plasma injections from the magnetosheath

  7. Pitch Angle Dependence of Drift Resonant Ions Observed by the Van Allen Probes

    Science.gov (United States)

    Rankin, R.; Wang, C.; Wang, Y.; Zong, Q. G.; Zhou, X.

    2017-12-01

    Acceleration and modulation of ring current ions by poloidal mode ULF waves is investigated. A simplified MHD model of ULF waves in a dipole magnetic field is presented that includes phase mixing to perpendicular scales determined by the ionospheric Pedersen conductivity. The wave model is combined with a full Lorentz force test particle code to study drift and drift bounce resonance wave-particle interactions. Ion trajectories are traced backward-in-time to an assumed form of the distribution function, and Liouville's method is used to reconstruct the phase space density response (PSD) poloidal mode waves observed by the Van Allen Probes. In spite of its apparent simplicity, simulations using the wave and test particle models are able to explain the acceleration of ions and energy dispersion observed by the Van Allen Probes. The paper focuses on the pitch angle evolution of the initial PSD as it responds to the action of ULF waves. An interesting aspect of the study is the formation of butterfly ion distributions as ions make periodic radial oscillations across L. Ions become trapped in an effective potential well across a limited range of L and follow trajectories that cause them to surf along constant phase fronts. The impications of this new trapping mechanism for both ions and electrons is discussed.

  8. Yeast Mitochondrial Interactosome Model: Metabolon Membrane Proteins Complex Involved in the Channeling of ADP/ATP

    Directory of Open Access Journals (Sweden)

    Benjamin Clémençon

    2012-02-01

    Full Text Available The existence of a mitochondrial interactosome (MI has been currently well established in mammalian cells but the exact composition of this super-complex is not precisely known, and its organization seems to be different from that in yeast. One major difference is the absence of mitochondrial creatine kinase (MtCK in yeast, unlike that described in the organization model of MI, especially in cardiac, skeletal muscle and brain cells. The aim of this review is to provide a detailed description of different partner proteins involved in the synergistic ADP/ATP transport across the mitochondrial membranes in the yeast Saccharomyces cerevisiae and to propose a new mitochondrial interactosome model. The ADP/ATP (Aacp and inorganic phosphate (PiC carriers as well as the VDAC (or mitochondrial porin catalyze the import and export of ADP, ATP and Pi across the mitochondrial membranes. Aacp and PiC, which appear to be associated with the ATP synthase, consist of two nanomotors (F0, F1 under specific conditions and form ATP synthasome. Identification and characterization of such a complex were described for the first time by Pedersen and co-workers in 2003.

  9. Ring Confidential Transactions

    Directory of Open Access Journals (Sweden)

    Shen Noether

    2016-12-01

    Full Text Available This article introduces a method of hiding transaction amounts in the strongly decentralized anonymous cryptocurrency Monero. Similar to Bitcoin, Monero is a cryptocurrency which is distributed through a proof-of-work “mining” process having no central party or trusted setup. The original Monero protocol was based on CryptoNote, which uses ring signatures and one-time keys to hide the destination and origin of transactions. Recently the technique of using a commitment scheme to hide the amount of a transaction has been discussed and implemented by Bitcoin Core developer Gregory Maxwell. In this article, a new type of ring signature, A Multilayered Linkable Spontaneous Anonymous Group signature is described which allows one to include a Pedersen Commitment in a ring signature. This construction results in a digital currency with hidden amounts, origins and destinations of transactions with reasonable efficiency and verifiable, trustless coin generation. The author would like to note that early drafts of this were publicized in the Monero Community and on the #bitcoin-wizards IRC channel. Blockchain hashed drafts are available showing that this work was started in Summer 2015, and completed in early October 2015. An eprint is also available at http://eprint.iacr.org/2015/1098.

  10. New method for solving inductive electric fields in the non-uniformly conducting ionosphere

    Directory of Open Access Journals (Sweden)

    H. Vanhamäki

    2006-10-01

    Full Text Available We present a new calculation method for solving inductive electric fields in the ionosphere. The time series of the potential part of the ionospheric electric field, together with the Hall and Pedersen conductances serves as the input to this method. The output is the time series of the induced rotational part of the ionospheric electric field. The calculation method works in the time-domain and can be used with non-uniform, time-dependent conductances. In addition, no particular symmetry requirements are imposed on the input potential electric field. The presented method makes use of special non-local vector basis functions called the Cartesian Elementary Current Systems (CECS. This vector basis offers a convenient way of representing curl-free and divergence-free parts of 2-dimensional vector fields and makes it possible to solve the induction problem using simple linear algebra. The new calculation method is validated by comparing it with previously published results for Alfvén wave reflection from a uniformly conducting ionosphere.

  11. New Method for Solving Inductive Electric Fields in the Ionosphere

    Science.gov (United States)

    Vanhamäki, H.

    2005-12-01

    We present a new method for calculating inductive electric fields in the ionosphere. It is well established that on large scales the ionospheric electric field is a potential field. This is understandable, since the temporal variations of large scale current systems are generally quite slow, in the timescales of several minutes, so inductive effects should be small. However, studies of Alfven wave reflection have indicated that in some situations inductive phenomena could well play a significant role in the reflection process, and thus modify the nature of ionosphere-magnetosphere coupling. The input to our calculation method are the time series of the potential part of the ionospheric electric field together with the Hall and Pedersen conductances. The output is the time series of the induced rotational part of the ionospheric electric field. The calculation method works in the time-domain and can be used with non-uniform, time-dependent conductances. In addition no particular symmetry requirements are imposed on the input potential electric field. The presented method makes use of special non-local vector basis functions called Cartesian Elementary Current Systems (CECS). This vector basis offers a convenient way of representing curl-free and divergence-free parts of 2-dimensional vector fields and makes it possible to solve the induction problem using simple linear algebra. The new calculation method is validated by comparing it with previously published results for Alfven wave reflection from uniformly conducting ionosphere.

  12. New method for solving inductive electric fields in the non-uniformly conducting ionosphere

    Science.gov (United States)

    Vanhamäki, H.; Amm, O.; Viljanen, A.

    2006-10-01

    We present a new calculation method for solving inductive electric fields in the ionosphere. The time series of the potential part of the ionospheric electric field, together with the Hall and Pedersen conductances serves as the input to this method. The output is the time series of the induced rotational part of the ionospheric electric field. The calculation method works in the time-domain and can be used with non-uniform, time-dependent conductances. In addition, no particular symmetry requirements are imposed on the input potential electric field. The presented method makes use of special non-local vector basis functions called the Cartesian Elementary Current Systems (CECS). This vector basis offers a convenient way of representing curl-free and divergence-free parts of 2-dimensional vector fields and makes it possible to solve the induction problem using simple linear algebra. The new calculation method is validated by comparing it with previously published results for Alfvén wave reflection from a uniformly conducting ionosphere.

  13. Ionospheric disturbance dynamo

    International Nuclear Information System (INIS)

    Blanc, M.; Richmond, A.D.

    1980-01-01

    A numerical simulation study of the thermospheric winds produced by auroral heating during magnetic storms, and of their global dynamo effects, establishes the main features of the ionospheric disturbanc dynamo. Driven by auroral heating, a Hadley cell is created with equatorward winds blowing above about 120 km at mid-latitudes. The transport of angular momentum by these winds produces a subrotation of the midlatitude thermosphere, or westward motion with respect to the earth. The westward winds in turn drive equatorward Pedersen currents which accumulate charge toward the equator, resulting in the generation of a poleward electric field, a westward E x B drift, and an eastward current. When realistic local time conductivity variations are simulated, the eastward mid-latitude current is found to close partly via lower latitudes, resulting in an 'anti-Sq' type of current vortex. Both electric field and current at low latitudes thus vary in opposition to their normal quiet-day behavior. This total pattern of distrubance winds, electric fields, and currents is superimposed upon the background quiet-day pattern. When the neutral winds are artificially confined on the nightside, the basic pattern of predominantly westward E x B plasma drifts still prevails on the nightside but no longer extends into the dayside. Considerable observational evidence exists, suggesting that the ionospheric disturbance dynamo has an appreciable influence on storm-time ionospheric electric fields at middle and low latitudes

  14. Relation of zonal plasma drift and wind in the equatorial F region as derived from CHAMP observations

    Directory of Open Access Journals (Sweden)

    J. Park

    2013-06-01

    Full Text Available In this paper we estimate zonal plasma drift in the equatorial ionospheric F region without counting on ion drift meters. From June 2001 to June 2004 zonal plasma drift velocity is estimated from electron, neutral, and magnetic field observations of Challenging Mini-satellite Payload (CHAMP in the 09:00–20:00 LT sector. The estimated velocities are validated against ion drift measurements by the Republic of China Satellite-1/Ionospheric Plasma and Electrodynamics Instrument (ROCSAT-1/IPEI during the same period. The correlation between the CHAMP (altitude ~ 400 km estimates and ROCSAT-1 (altitude ~ 600 km observations is reasonably high (R ≈ 0.8. The slope of the linear regression is close to unity. However, the maximum westward drift and the westward-to-eastward reversal occur earlier for CHAMP estimates than for ROCSAT-1 measurements. In the equatorial F region both zonal wind and plasma drift have the same direction. Both generate vertical currents but with opposite signs. The wind effect (F region wind dynamo is generally larger in magnitude than the plasma drift effect (Pedersen current generated by vertical E field, thus determining the direction of the F region vertical current.

  15. Modeling the interaction of a heavily beam loaded SRF cavity with its low-level RF feedback loops

    Science.gov (United States)

    Liu, Zong-Kai; Wang, Chaoen; Chang, Lung-Hai; Yeh, Meng-Shu; Chang, Fu-Yu; Chang, Mei-Hsia; Chang, Shian-Wen; Chen, Ling-Jhen; Chung, Fu-Tsai; Lin, Ming-Chyuan; Lo, Chih-Hung; Yu, Tsung-Chi

    2018-06-01

    A superconducting radio frequency (SRF) cavity provides superior stability to power high intensity light sources and can suppress coupled-bunch instabilities due to its smaller impedance for higher order modes. Because of these features, SRF cavities are commonly used for modern light sources, such as the TLS, CLS, DLS, SSRF, PLS-II, TPS, and NSLS-II, with an aggressive approach to operate the light sources at high beam currents. However, operating a SRF cavity at high beam currents may result with unacceptable stability problems of the low level RF (LLRF) system, due to drifts of the cavity resonant frequency caused by unexpected perturbations from the environment. As the feedback loop gets out of control, the cavity voltage may start to oscillate with a current-dependent characteristic frequency. Such situations can cause beam abort due to the activation of the interlock protection system, i.e. false alarm of quench detection. This malfunction of the light source reduces the reliability of SRF operation. Understanding this unstable mechanism to prevent its appearance becomes a primary task in the pursuit of highly reliable SRF operation. In this paper, a Pedersen model, including the response of the LLRF system, was used to simulate the beam-cavity interaction of a SRF cavity under heavy beam loading. Causes for the onset of instability at high beam current will be discussed as well as remedies to assure the design of a stable LLRF system.

  16. Spilleregler i musikterapi med voksne - oversigter fra faglitteraturen

    Directory of Open Access Journals (Sweden)

    Ulla Holck

    2005-02-01

    Full Text Available Artiklen gennemgår udvalgt faglitteratur, der på et overordnet plan beskriver typer af spilleregler i musikterapi med (fortrinsvis voksne klientgrupper. Udgangspunktet er Priestleys anvendelse af begrebet, og hendes inddeling af spilleregler i forhold til forskellige teknikker gennemgås, efterfulgt af en præsentation af opdelinger lavet af henholdsvis Pedersen & Scheiby, Bruscia og Wigram. En af forskellene på opfattelsen af spillereglernes karakter og anvendelse handler om, hvorvidt spillereglerne udelukkende bør have et referentielt indhold med udgangspunkt i klientens psykiske materiale, eller om også rent musikalske (eller nonreferentiellespilleregler kan siges at have en terapeutisk effekt. Artiklens forfatter ser i stedet spørgsmålet i lyset af mange klienters behov for en gradvis introduktion til klinisk improvisation og inddrager i den sammenhæng litteratur om introduktion og assessment af bl.a. Wigram, Hannibal og Jensen. Artiklen er den første i en serie, hvis overordnede mål er at indsamle viden og erfaring om anvendelse af spilleregler i forhold til forskellige klientgrupper. Anden del omhandler udvikling af spilleregler i forhold til børneklientgrupper og findes i næste kapitel i dette årsskrift.

  17. Assessment of productivity loss in air-conditioned buildings using PMV index

    Energy Technology Data Exchange (ETDEWEB)

    Kosonen, R. [Halton OY, Kausala (Finland); Tan, F. [CapitaLand Commercial Limited, Singapore (Singapore)

    2004-07-01

    This theoretical study reports on the assessment of productivity loss in air-conditioned office buildings using the PMV approach and makes use of Wyon's reviews [D.P. Wyon, P.O. Fanger, B.W. Olesen, C.J.K. Pedersen, The mental performance of subjects clothed for comfort at two different air temperatures, Ergonomics 18 (1975) 358-374; D.P. Wyon, Individual microclimate control: required range, probable benefits and current feasibility, in: Proceedings of Indoor Air '96, Institute of Public Health, Tokyo, 1996; D.P. Wyon, Indoor environmental effects on productivity. IAQ 96 Paths to better building environments/Keynote address. Y. Kevin. Atlanta, ASHRAE, pp. 5-15] as the basis to compare and to relate how the productivity loss could be minimised through improved thermal comfort design criteria. The finding shows that task-related performance is significantly correlated with the human perception of thermal environment that in turn is dependent on temperatures. Different combinations of thermal criteria (air velocity, clo, metabolic, etc.) can lead to similar PMV value and the PMV equation is useful to predict productivity loss that is due to the rate of change in thermal conditions. The study also highlights the issues that remain to be resolved in future research. (author)

  18. COMPOSITION OF STAFF REVIEW ADVISORY BODIES - 2002

    CERN Multimedia

    Human Resources Division

    2002-01-01

    For the present staff review, the advisory bodies set up to prepare recommendations are composed as follows: Senior Staff Advancement Committee (SSAC) Cristoforo BENVENUTI/EST [Convener] David PLANE/EP Peter SCHMID/EP Technical Engineers & Administrative Careers Committee (TEACC) Robin LAUCKNER/SL [Chairman] Flemming PEDERSEN/PS Lucie LINSSEN/EP Dietrich SCHINZEL/EP Marcel MOTTIER/EST Louis WALCKIERS/LHC Long-term contract Boards (LTCBs) (Categories 2 & 5a) Tiziano CAMPORESI/EP [Convener] Florence RANJARD/EP [Alternate] Jacques GRUBER/PS [until 30.6.2002] Roger BAILEY/SL [from 1.7. 2002] Peter SIEVERS/LHC [Alternate] Doris FORKEL-WIRTH/TIS Pierre NININ/ST [Alternate] Sue FOFFANO/AS Maarten WILBERS/DSU [Alternate] Werner ZAPF/HR[Secretary] LTCB 2 Categories 3, 4, 5b & 5c) Véronique PARIS/SL [Convener] Fabien PERRIOLLAT/PS [Alternate] Mats WILHELMSSON/ST Charles NUTTALL/TIS [Alternate] Lucie LINSSEN/EP Alfredo PLACCI/EP [Alternate] Patrick GEERAER...

  19. A Robust Motion Artifact Detection Algorithm for Accurate Detection of Heart Rates From Photoplethysmographic Signals Using Time-Frequency Spectral Features.

    Science.gov (United States)

    Dao, Duy; Salehizadeh, S M A; Noh, Yeonsik; Chong, Jo Woon; Cho, Chae Ho; McManus, Dave; Darling, Chad E; Mendelson, Yitzhak; Chon, Ki H

    2017-09-01

    Motion and noise artifacts (MNAs) impose limits on the usability of the photoplethysmogram (PPG), particularly in the context of ambulatory monitoring. MNAs can distort PPG, causing erroneous estimation of physiological parameters such as heart rate (HR) and arterial oxygen saturation (SpO2). In this study, we present a novel approach, "TifMA," based on using the time-frequency spectrum of PPG to first detect the MNA-corrupted data and next discard the nonusable part of the corrupted data. The term "nonusable" refers to segments of PPG data from which the HR signal cannot be recovered accurately. Two sequential classification procedures were included in the TifMA algorithm. The first classifier distinguishes between MNA-corrupted and MNA-free PPG data. Once a segment of data is deemed MNA-corrupted, the next classifier determines whether the HR can be recovered from the corrupted segment or not. A support vector machine (SVM) classifier was used to build a decision boundary for the first classification task using data segments from a training dataset. Features from time-frequency spectra of PPG were extracted to build the detection model. Five datasets were considered for evaluating TifMA performance: (1) and (2) were laboratory-controlled PPG recordings from forehead and finger pulse oximeter sensors with subjects making random movements, (3) and (4) were actual patient PPG recordings from UMass Memorial Medical Center with random free movements and (5) was a laboratory-controlled PPG recording dataset measured at the forehead while the subjects ran on a treadmill. The first dataset was used to analyze the noise sensitivity of the algorithm. Datasets 2-4 were used to evaluate the MNA detection phase of the algorithm. The results from the first phase of the algorithm (MNA detection) were compared to results from three existing MNA detection algorithms: the Hjorth, kurtosis-Shannon entropy, and time-domain variability-SVM approaches. This last is an approach

  20. Information, communication and education on climate change. European perspectives

    Energy Technology Data Exchange (ETDEWEB)

    Filho, W.L.; Mannke, F. [TuTech Innovation GmbH, Hamburg (Germany); Schmidt-Thome, P. (eds.) [Geologinen Tutkimuslaitos, Espoo (Finland)

    2007-07-01

    It is now beyond any doubt that climate change represents a major threat to the environmental, social and economic well being of the planet. The book under consideration is an attempt to contribute to the global debate on climate change by outlining some educational methods, approaches and projects which have been focusing on climate issues in Europe. The book under consideration consists of the following chapters: (a) ESPACE - A New Transnational Approach to Adapting to the Impacts of Climate Change (Jill Cook, Doogie Black, Angela Bentham, Tania Stadsbader, Jorn Peters, Lesley van Dijk, Mark Goldthorpe, Tim Yair, Fran Wallington, Meinte de Hoogh, Michael Belau); (b) Communicating Climate Change Impacts - an Approach Derived from two Regional Development Projects (Philipp Schmidt-Thome, Johannes Klein); (c) Baltex Assessment of Climate Change for the Baltic Sea Basin (BACC) (Hans von Storch, Anders Omstedt, Hans-Joerg Isemer); (d) Promoting Climate friendly Communities in Northamptonshire, United Kingdam (Philip Gray, Shane Conway); (e) Climite Change Mitigation and Sustainability: Educational Issues (Remigijus Ciegis; Dalia Streimikiene, Dalia Gineitiene); (f) Case Study Research as Bridge Builder between Science and the Society - The Rationale behind the ASTRA 2005 Winter Storm Study (Simo Haanpaeae, Lasse Peltonen); (g) Educational Actions in Italy to face the Problem of Climate Change (Eugenia Aloj, Mariagrazia De Castro, Anna Zollo); (h) Teaching Global Climate Change as a Controversial Issue - Active Learning in Higher Education (Evangelos I. Manolas); (i) Regional Climate Change and Coasts - A Case Study on Perception, Information, Dissemination and Education (Gerald Schernewski, Steffen Bock, Holger Janssen, Nardine Loeser, Annemone Himielorz); (j) KLARA-Net: An Interdisciplinary Action Oriented Approach on Climate Change Adaptation (Birte Frommer; Lena Herlitzius); (k) Climate Change, Featuring the ACCROTELM Project: Dissemination of a European RTD

  1. Combined determination of highly sensitive troponin T and copeptin for early exclusion of acute myocardial infarction: first experience in an emergency department of a general hospital

    Directory of Open Access Journals (Sweden)

    Lotze U

    2011-08-01

    Full Text Available Ulrich Lotze1, Holger Lemm2, Anke Heyer2, Karin Müller31Department of Internal Medicine, German Red Cross Hospital Sondershausen, Sondershausen, 2Department of Internal Medicine, 3Department of Laboratory Medicine, Saale-Unstrut Hospital Naumburg, Naumburg, GermanyBackground: The purpose of this observational study was to test the diagnostic performance of the Elecsys® troponin T high-sensitive system combined with copeptin measurement for early exclusion of acute myocardial infarction (MI in clinical practice.Methods: Troponin T high-sensitive (diagnostic cutoff: <14 pg/mL and copeptin (diagnostic cutoff: <14 pmol/L levels were determined at admission in addition to other routine laboratory parameters in patients with suspected acute MI presenting to the emergency department of a general hospital over a period of five months.Results: Data from 142 consecutive patients (mean age 71.2 ± 13.5 years, 76 men were analyzed. Final diagnoses were acute MI in 13 patients (nine ST elevation MI, four non-ST elevation MI, 9.2% unstable angina pectoris in three (2.1%, cardiac symptoms not primarily associated with myocardial ischemia in 79 (55.6%, and noncardiac disease in 47 patients (33.1%. The patients with acute MI were younger and had higher troponin T high-sensitive and copeptin values than patients without acute MI. Seventeen patients had very high copeptin values (>150 pmol/L, one of whom had a level of >700 pmol/L and died of pulmonary embolism. A troponin T high-sensitive level of <14 pg/mL in combination with copeptin <14 pmol/L at initial presentation ruled out acute MI in 45 of the 142 patients (31.7%, each with a sensitivity and negative predictive value of 100%.Conclusion: According to this early experience, a single determination of troponin T high-sensitive and copeptin may enable early and accurate exclusion of acute MI in one third of patients, even in an emergency department of a general hospital.Keywords: highly sensitive troponin T

  2. Non-imidazole-based histamine H3 receptor antagonists with anticonvulsant activity in different seizure models in male adult rats

    Directory of Open Access Journals (Sweden)

    Sadek B

    2016-11-01

    Full Text Available Bassem Sadek,1 Ali Saad,1 Gniewomir Latacz,2 Kamil Kuder,2 Agnieszka Olejarz,2 Tadeusz Karcz,2 Holger Stark,3 Katarzyna Kieć-Kononowicz2 1Department of Pharmacology and Therapeutics, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates; 2Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University Medical College, Kraków, Poland; 3Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany Abstract: A series of twelve novel non-imidazole-based ligands (3–14 was developed and evaluated for its in vitro binding properties at the human histamine H3 receptor (hH3R. The novel ligands were investigated for their in vivo protective effects in different seizure models in male adult rats. Among the H3R ligands (3–14 tested, ligand 14 showed significant and dose-dependent reduction in the duration of tonic hind limb extension in maximal electroshock (MES-induced seizure model subsequent to acute systemic administration (5, 10, and 20 mg/kg, intraperitoneally, whereas ligands 4, 6, and 7 without appreciable protection in MES model were most promising in pentylenetetrazole (PTZ model. Moreover, the protective effect observed for ligand 14 in MES model was lower than that observed for the reference drug phenytoin and was entirely abrogated when rats were co-administered with the brain-penetrant H1R antagonist pyrilamine (PYR but not the brain-penetrant H2R antagonist zolantidine (ZOL, demonstrating that histaminergic neurotransmission by activation of postsynaptically located H1Rs seems to be involved in the protective action. On the contrary, PYR and ZOL failed to abrogate the full protection provided by 4 in PTZ model and the moderate protective effect by 14 in strychnine (STR model. Moreover, the experimental and in silico estimation of properties such as metabolism was

  3. PREFACE: 21st International Conference on Laser Spectroscopy - ICOLS 2013

    Science.gov (United States)

    Budker, Dmitry; Häffner, Hartmut; Müller, Holger

    2013-12-01

    videos of the reception and banquet presentations available at the conference web site https://icols.berkeley.edu/. On behalf of the organizing and program committees, Berkeley, October 2013 Dmitry Budker, Hartmut Häffner, and Holger Müller

  4. Mask humidity during CPAP: influence of ambient temperature, heated humidification and heated tubing

    Directory of Open Access Journals (Sweden)

    Nilius G

    2018-05-01

    Full Text Available Georg Nilius,1,2 Ulrike Domanski,1 Maik Schroeder,1 Holger Woehrle,3,4 Andrea Graml,4 Karl-Josef Franke,1,2 1Helios Klinik Hagen-Ambrock, Department of Pneumology, Hagen, Germany; 2Department of Internal Medicine, Witten-Herdecke University, Witten, Germany; 3Sleep and Ventilation Center Blaubeuren, Respiratory Center Ulm, Ulm, Germany; 4ResMed Science Center, ResMed Germany, Martinsried, Germany Purpose: Mucosal drying during continuous positive airway pressure (CPAP therapy is problematic for many patients. This study assessed the influence of ambient relative humidity (rH and air temperature (T in winter and summer on mask humidity during CPAP, with and without mask leak, and with or without heated humidification ± heated tubing. Methods: CPAP (8 and 12 cmH2O without humidification (no humidity [nH], with heated humidification controlled by ambient temperature and humidity (heated humidity [HH] and HH plus heated tubing climate line (CL, with and without leakage, were compared in 18 subjects with OSA during summer and winter. Results: The absolute humidity (aH and the T inside the mask during CPAP were significantly lower in winter versus summer under all applied conditions. Overall, absolute humidity differences between summer and winter were statistically significant in both HH and CL vs. nH (p < 0.05 in the presence and absence of mouth leak. There were no significant differences in aH between HH and CL. However, in-mask temperature during CL was higher (p < 0.05 and rH lower than during HH. In winter, CPAP with CL was more likely to keep rH constant at 80% than CPAP without humidification or with standard HH. Conclusion: Clinically-relevant reductions in aH were documented during CPAP given under winter conditions. The addition of heated humidification, using a heated tube to avoid condensation is recommended to increase aH, which could be useful in CPAP users complaining of nose and throat symptoms. Keywords: continuous positive

  5. Regadenoson in the detection of coronary artery disease

    Directory of Open Access Journals (Sweden)

    Christiane Buhr

    2008-04-01

    Full Text Available Christiane Buhr1, Mario Gössl2, Raimund Erbel1, Holger Eggebrecht11Department of Cardiology, West-German Heart Center Essen, University of Duisburg-Essen, Essen, Germany; 2Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, MN 55905, USAAbstract: Myocardial perfusion studies use either physical exercise or pharmacologic vasodilator stress to induce maximum myocardial hyperemia. Adenosine and dipyridamole are the most commonly used agents to induce coronary arterial vasodilation for myocardial perfusion imaging. Both cause frequent undesirable side-effects. Because of its ultrashort half-life, adenosine must be administered by constant intravenous infusion during the examination. A key feature of an ideal A2A agonist for myocardial perfusion imaging studies would be an optimal level and duration of hyperemic response. Drugs with a longer half-time and more selective A2A adenosine receptor agonism, such as regadenoson, should theoretically result in a similar degree of coronary vasodilation with fewer or less severe side-effects than non-selective, ultrashort-lasting adenosine receptor stimulation. The available preclinical and clinical data suggest that regadenoson is a highly subtype-selective, potent, low-affinity A2A adenosine receptor agonist that holds promise for future use as a coronary vasodilator in myocardial perfusion imaging studies. Infusion of regadenoson achieves maximum coronary hyperemia that is equivalent to adenosine. After a single bolus infusion over 10 s, hyperemia is maintained significantly longer (approximately 2–5 min than with adenosine, which should facilitate radionuclide distribution for myocardial perfusion imaging studies. In comparison with the clinically competitive A2A adenosine receptor agonist binodenoson, regadenoson has a several-fold shorter duration of action, although the magnitude of hyperemic response is comparable between the two. The more rapid termination of action of regadenoson

  6. A simple heuristic for Internet-based evidence search in primary care: a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Eberbach A

    2016-08-01

    Full Text Available Andreas Eberbach,1 Annette Becker,1 Justine Rochon,2 Holger Finkemeler,1Achim Wagner,3 Norbert Donner-Banzhoff1 1Department of Family and Community Medicine, Philipp University of Marburg, Marburg, Germany; 2Institute of Medical Biometry and Informatics, University of Heidelberg, Heidelberg, Germany; 3Department of Sport Medicine, Justus-Liebig-University of Giessen, Giessen, Germany Background: General practitioners (GPs are confronted with a wide variety of clinical questions, many of which remain unanswered. Methods: In order to assist GPs in finding quick, evidence-based answers, we developed a learning program (LP with a short interactive workshop based on a simple ­three-step-heuristic to improve their search and appraisal competence (SAC. We evaluated the LP ­effectiveness with a randomized controlled trial (RCT. Participants (intervention group [IG] n=20; ­control group [CG] n=31 rated acceptance and satisfaction and also answered 39 ­knowledge ­questions to assess their SAC. We controlled for previous knowledge in content areas covered by the test. Results: Main outcome – SAC: within both groups, the pre–post test shows significant (P=0.00 improvements in correctness (IG 15% vs CG 11% and confidence (32% vs 26% to find evidence-based answers. However, the SAC difference was not significant in the RCT. Other measures: Most workshop participants rated “learning atmosphere” (90%, “skills acquired” (90%, and “relevancy to my practice” (86% as good or very good. The ­LP-recommendations were implemented by 67% of the IG, whereas 15% of the CG already conformed to LP recommendations spontaneously (odds ratio 9.6, P=0.00. After literature search, the IG showed a (not significantly higher satisfaction regarding “time spent” (IG 80% vs CG 65%, “quality of information” (65% vs 54%, and “amount of information” (53% vs 47%.Conclusion: Long-standing established GPs have a good SAC. Despite high acceptance, strong

  7. The cost of dysphagia in geriatric patients

    Directory of Open Access Journals (Sweden)

    Westmark S

    2018-06-01

    Full Text Available Signe Westmark,1 Dorte Melgaard,1,2 Line O Rethmeier,3 Lars Holger Ehlers3 1Center for Clinical Research, North Denmark Regional Hospital, Hjørring, Denmark; 2Department of Physiotherapy and Occupational Therapy, North Denmark Regional Hospital, Hjørring, Denmark; 3Danish Center for Healthcare Improvements, Aalborg University, Aalborg, Denmark Objectives: To estimate the annual cost at the hospital and in the municipality (social care due to dysphagia in geriatric patients.Design: Retrospective cost analysis of geriatric patients with dysphagia versus geriatric patients without dysphagia 1 year before hospitalization.Setting: North Denmark Regional Hospital, Hjørring Municipality, Frederikshavn Municipality, and Brønderslev Municipality.Subjects: A total of 258 hospitalized patients, 60 years or older, acute hospitalized in the geriatric department.Materials and methods: Volume-viscosity swallow test and the Minimal Eating Observation Form-II were conducted for data collection. A Charlson Comorbidity Index score measured comorbidity, and functional status was measured by Barthel-100. To investigate the cost of dysphagia, patient-specific data on health care consumption at the hospital and in the municipality (nursing, home care, and training were collected from medical registers and records 1 year before hospitalization including the hospitalization for screening for dysphagia. Multiple linear regression analyses were conducted to determine the relationship between dysphagia and hospital and municipality costs, respectively, adjusting for age, gender, and comorbidity.Results: Patients with dysphagia were significantly costlier than patients without dysphagia in both hospital (p=0.013 and municipality costs (p=0.028 compared to patients without dysphagia. Adjusted annual hospital costs in patients with dysphagia were 27,347 DKK (3,677 EUR, 4,282 USD higher than patients without dysphagia at the hospital, and annual health care costs in the

  8. "Incidental fear cues increase monetary loss aversion": Correction to Schulreich, Gerhardt, and Heekeren (2016).

    Science.gov (United States)

    2016-12-01

    Reports an error in "Incidental fear cues increase monetary loss aversion" by Stefan Schulreich, Holger Gerhardt and Hauke R. Heekeren ( Emotion , 2016[Apr], Vol 16[3], 402-412). In the current article, there was an error in the Study 2 portion of the article. The fourth paragraph of the Results section should read as follows: Performing the same analyses as in Study 1, we found an effect of incidental fear cues on decision behavior. Participants accepted fewer gambles in the fearful-face condition (32.77%) than in the neutral-face condition (33.96%), with Z = -2.187, p = .027, d = -0.998 in the Wilcoxon signed-ranks test and β = 0.012, SE = 0.0053, F(1, 21) = 4.434, p = .047, partial η² = .174 in the linear regression. This suggests increased risk aversion in the fearful-face condition. Concerning personality, however, there were no significant between-subjects effects or between-within interaction effects (all ps = .349). (The following abstract of the original article appeared in record 2015-52358-001.) In many everyday decisions, people exhibit loss aversion-a greater sensitivity to losses relative to gains of equal size. Loss aversion is thought to be (at least partly) mediated by emotional-in particular, fear-related-processes. Decision research has shown that even incidental emotions, which are unrelated to the decision at hand, can influence decision making. The effect of incidental fear on loss aversion, however, is thus far unclear. In two studies, we experimentally investigated how incidental fear cues, presented during (Study 1) or before (Study 2) choices to accept or reject mixed gambles over real monetary stakes, influence monetary loss aversion. We find that the presentation of fearful faces, relative to the presentation of neutral faces, increased risk aversion-an effect that could be attributed to increased loss aversion. The size of this effect was moderated by psychopathic personality: Fearless dominance, in particular its interpersonal facet

  9. Boron diffusion in strained and strain-relaxed SiGe

    International Nuclear Information System (INIS)

    Wang, C.C.; Sheu, Y.M.; Liu, Sally; Duffy, R.; Heringa, A.; Cowern, N.E.B.; Griffin, P.B.

    2005-01-01

    SiGe has been utilized for aggressive CMOS technologies development recently and there are many references [M. Shima, T. Ueno, T. Kumise, H. Shido, Y. Sakuma, S. Nakamura, Symposium on VLSI Technology Technical Digest, 2002, pp. 94-95; T. Ghani, M. Armstrong, C. Auth, M. Bost, P. Charvat, G. Glass, T. Hoffmann, K. Johnson, C. Kenyon, J. Klaus, B. McIntyre, K. Mistry, A. Murthy, J. Sandford, M. Silberstein, S. Sivakumar, P. Smith, K. Zawadzki, S. Thompson, M. Bohr, International Electron Devices Meeting Technical Digest, December 2003, pp. 978-980; P. Bai, C. Auth, S. Balakrishnan, M. Bost, R. Brain, V. Chikarmane, R. Heussner, M. Hussein, J. Hwang, D. Ingerly, R. James, J. Jeong, C. Kenyon, E. Lee, S. Lee, N. Lindert, M. Liu, Z. Ma, T. Marieb, A. Murthy, R. Nagisetty, S. Natarajan, J. Neirynck, A. Ott, C. Parker, J. Sebastian, R. Shaheed, S. Sivakumar, J. Steigerwald, S. Tyagi, C. Weber, B. Woolery, A. Yeoh, K. Zhang, M. Bohr, International Electron Devices Meeting Technical Digest, December 2004, pp. 657-660] presenting the advantages brought by it. A better understanding regarding the boron diffusion behavior within and in the vicinity of SiGe is necessary to optimize the extension and the source/drain in pMOSFET. In order to achieve the goal, both effects from mechanical strain and Ge doping on boron diffusion have been investigated. However, only a few publications discuss the impacts of both. Furthermore, most researches investigate these two effects under the conditions of low boron concentration [P. Kuo, J.L. Hoyt, J.F. Gibbons, J.E. Turner, D. Lefforge, Appl. Phys. Lett. 66 (January (5)) (1995) 580-582; N.R. Zangenberg, J. Fage-Pedersen, J. Lundsgaard Hansen, A. Nylandsted Larsen, J. Appl. Phys. 94 (September (6)) (2003) 3883-3890] and high thermal budget anneal [P. Kuo, J.L. Hoyt, J.F. Gibbons, J.E. Turner, D. Lefforge, Appl. Phys. Lett. 66 (January (5)) (1995) 580-582; N.R. Zangenberg, J. Fage-Pedersen, J. Lundsgaard Hansen, A. Nylandsted Larsen, J. Appl

  10. Evaluation of Wax Deposition and Its Control During Production of Alaska North Slope Oils

    Energy Technology Data Exchange (ETDEWEB)

    Tao Zhu; Jack A. Walker; J. Liang

    2008-12-31

    /STB. The bubblepoint pressure for live oil samples varied between 1600 psi and 2100 psi. Wax precipitation is one of the most important phenomena in wax deposition and, hence, needs to be modeled. There are various models present in the literature. Won's model, which considers the wax phase as a non-ideal solution, and Pedersen's model, which considers the wax phase as an ideal solution, were compared. Comparison indicated that Pedersen's model gives better results, but the assumption of wax phase as an ideal solution is not realistic. Hence, Won's model was modified to consider different precipitation characteristics of the various constituents in the hydrocarbon fraction. The results obtained from the modified Won's model were compared with existing models, and it was found that predictions from the modified model are encouraging.

  11. COMPRIMENTO DA ESTACA DE RAMO NO ENRAIZAMENTO DE GINSENG BRASILEIRO (Pfaffia glomerata SHOOT CUTTING LENGTH ON ROOTING OF BRAZILIAN GINSENG (Pfaffia glomerata

    Directory of Open Access Journals (Sweden)

    Fernando Teixeira Nicoloso

    2001-02-01

    Full Text Available A Pfaffia glomerata (Spreng. Pedersen é uma dentre várias espécies conhecidas como ginseng brasileiro e é usada como planta medicinal. O objetivo desse trabalho foi determinar se o comprimento da estaca de ramo influencia o enraizamento da P. glomerata. Os tratamentos usados consistiram de três comprimentos de estacas (10, 15 e 20cm; ± 1cm de variação. As estacas foram obtidas dos 70cm basais de ramos, com 80 a 140cm de comprimento, de plantas possuindo dois anos de idade, cultivadas no Jardim Botânico da UFSM. Utilizou-se o delineamento experimental de blocos ao acaso com três repetições e 30 estacas por unidade experimental. O bloco experimental consistiu de uma bandeja plástica com capacidade para 36 litros de solução nutritiva. O experimento foi instalado no dia 15 de julho de 1998 e conduzido por 44 dias sob condições controladas de temperatura, luminosidade e umidade do ar. Os resultados indicaram que (i o tamanho da estaca não afeta a percentagem de enraizamento, a produção de massa seca de folhas e raízes. Por outro lado, as mudas obtidas de estacas de 10cm apresentam maior número de brotações, comprimento das brotações, massa seca de talos e massa seca total produzida por estaca que as de 20cm; e (ii o uso de estacas com 10cm de comprimento é viável e, conseqüentemente, possibilita a obtenção de um maior número de estacas por ramo.Pfaffia glomerata (Spreng. Pedersen is among several species known as Brazilian ginsengs and it is used as medicinal plant. The aim of this work was to evaluate the length of the shoot cuttings on rooting of P. glomerata. Treatments consisted of three length of cuttings (10, 15, and 20cm; ± 1cm of variation. Cuttings were obtained from the 70cm of the basal portion from shoots of 80 to 140cm of length, from two-year-old plants grown in the Botanical Garden at State University of Santa Maria, RS, Brazil. Treatments were distributed in a completely randomized block design with

  12. Shallow water radio-magnetotelluric (RMT) measurements in urban environment: A case study from Stockholm city

    Science.gov (United States)

    Mehta, Suman; Bastani, Mehrdad; Malehmir, Alireza; Wang, Shunguo; Pedersen, Laust

    2014-05-01

    of the impedance tensor were obtained by the parametric representation combined with a Truncated Singular Value Decomposition (TSVD) regularization of Bastani and Pedersen (2001). The processed data were then inverted to obtain 2D resistivity models. The resulting models along 23 lines correlate well and image variation of water depth, thickness of subaqueous sediments as well as the depth to crystalline bedrock. Low resistivity zones observed in the bedrock coincide well with the low velocity zones identified in refraction seismic surveys available along the RMT lines, indicating the presence of possible fracture zones in the bedrock. The experiment illustrates that the RMT methods can be well adapted to this type of environment; it is fast and cost-effective in shallow water especially in urban settings. Acknowledgments: Formas, SGU, BeFo, SBUF, Skanska, Boliden, FQM and NGI References: Bastani, M., 2001, EnviroMT - a new Controlled Source/Radio Magnetotelluric System: Ph.D. thesis, ISBN 91-554-5051-2, Uppsala University. Bastani, M. and Pedersen, L. B., 2001, Estimation of magnetotelluric transfer functions from radio transmitters. GEOPHYSICS, 66, 1038-1051.

  13. Azimuthal magnetic fields in Saturn’s magnetosphere: effects associated with plasma sub-corotation and the magnetopause-tail current system

    Directory of Open Access Journals (Sweden)

    E. J. Bunce

    Full Text Available We calculate the azimuthal magnetic fields expected to be present in Saturn’s magnetosphere associated with two physical effects, and compare them with the fields observed during the flybys of the two Voyager spacecraft. The first effect is associated with the magnetosphere-ionosphere coupling currents which result from the sub-corotation of the magnetospheric plasma. This is calculated from empirical models of the plasma flow and magnetic field based on Voyager data, with the effective Pedersen conductivity of Saturn’s ionosphere being treated as an essentially free parameter. This mechanism results in a ‘lagging’ field configuration at all local times. The second effect is due to the day-night asymmetric confinement of the magnetosphere by the solar wind (i.e. the magnetopause and tail current system, which we have estimated empirically by scaling a model of the Earth’s magnetosphere to Saturn. This effect produces ‘leading’ fields in the dusk magnetosphere, and ‘lagging’ fields at dawn. Our results show that the azimuthal fields observed in the inner regions can be reasonably well accounted for by plasma sub-corotation, given a value of the effective ionospheric Pedersen conductivity of ~ 1–2 mho. This statement applies to field lines mapping to the equator within ~ 8 RS (1 RS is taken to be 60 330 km of the planet on the dayside inbound passes, where the plasma distribution is dominated by a thin equatorial heavy-ion plasma sheet, and to field lines mapping to the equator within ~ 15 RS on the dawn side outbound passes. The contributions of the magnetopause-tail currents are estimated to be much smaller than the observed fields in these regions. If, however, we assume that the azimuthal fields observed in these regions are not due to sub-corotation but to some other process, then the above effective conductivities define an upper limit, such that values above ~ 2 mho can definitely be

  14. Detection of Hot Halo Gets Theory Out of Hot Water

    Science.gov (United States)

    2006-02-01

    Scientists using NASA's Chandra X-ray Observatory have detected an extensive halo of hot gas around a quiescent spiral galaxy. This discovery is evidence that galaxies like our Milky Way are still accumulating matter from the gradual inflow of intergalactic gas. "What we are likely witnessing here is the ongoing galaxy formation process," said Kristian Pedersen of the University of Copenhagen, Denmark, and lead author of a report on the discovery. Chandra observations show that the hot halo extends more than 60,000 light years on either side of the disk of the galaxy known as NGC 5746. The detection of such a large halo alleviates a long-standing problem for the theory of galaxy formation. Spiral galaxies are thought to form from enormous clouds of intergalactic gas that collapse to form giant, spinning disks of stars and gas. Chandra X-ray Image of NGC 5746 Chandra X-ray Image of NGC 5746 One prediction of this theory is that large spiral galaxies should be immersed in halos of hot gas left over from the galaxy formation process. Hot gas has been detected around spiral galaxies in which vigorous star formation is ejecting matter from the galaxy, but until now hot halos due to infall of intergalactic matter have not been detected. "Our observations solve the mystery of the missing hot halos around spiral galaxies," said Pedersen. "The halos exist, but are so faint that an extremely sensitive telescope such as Chandra is needed to detect them." DSS Optical Image of NGC 5746 DSS Optical Image of NGC 5746 NGC 5746 is a massive spiral galaxy about a 100 million light years from Earth. Its disk of stars and gas is viewed almost edge-on. The galaxy shows no signs of unusual star formation, or energetic activity from its nuclear region, making it unlikely that the hot halo is produced by gas flowing out of the galaxy. "We targeted NGC 5746 because we thought its distance and orientation would give us the best chance to detect a hot halo caused by the infall of

  15. FOCUS ON GRAPHENE

    International Nuclear Information System (INIS)

    Peres, N M R; Ribeiro, Ricardo M

    2009-01-01

    Graphene physics is currently one of the most active research areas in condensed matter physics. Countless theoretical and experimental studies have already been performed, targeting electronic, magnetic, thermal, optical, structural and vibrational properties. Also, studies that modify pristine graphene, aiming at finding new physics and possible new applications, have been considered. These include patterning nanoribbons and quantum dots, exposing graphene's surface to different chemical species, studying multilayer systems, and inducing strain and curvature (modifying in this way graphene's electronic properties). This focus issue includes many of the latest developments on graphene research. Focus on Graphene Contents The effect of sublattice symmetry breaking on the electronic properties of doped graphene A Qaiumzadeh and R Asgari Interfaces within graphene nanoribbons J Wurm, M Wimmer, I Adagideli, K Richter and H U Baranger Weak localization and transport gap in graphene antidot lattices J Eroms and D Weiss Electronic properties of graphene antidot lattices J A Fuerst, J G Pedersen, C Flindt, N A Mortensen, M Brandbyge, T G Pedersen and A-P Jauho Splitting of critical energies in the n=0 Landau level of graphene Ana L C Pereira Double-gated graphene-based devices S Russo, M F Craciun, M Yamamoto, S Tarucha and A F Morpurgo Pinning and switching of magnetic moments in bilayer graphene Eduardo V Castro, M P Lopez-Sancho and M A H Vozmediano Electronic transport properties of graphene nanoribbons Katsunori Wakabayashi, Yositake Takane, Masayuki Yamamoto and Manfred Sigrist Many-body effects on out-of-plane phonons in graphene J Gonzalez and E Perfetto Graphene zigzag ribbons, square lattice models and quantum spin chains Mahdi Zarea and Nancy Sandler On the universal ac optical background in graphene V P Gusynin, S G Sharapov and J P Carbotte Heat conduction in graphene: experimental study and theoretical interpretation S Ghosh, D L Nika, E P Pokatilov and A A

  16. Self-consistent modeling of induced magnetic field in Titan's atmosphere accounting for the generation of Schumann resonance

    Science.gov (United States)

    Béghin, Christian

    2015-02-01

    This model is worked out in the frame of physical mechanisms proposed in previous studies accounting for the generation and the observation of an atypical Schumann Resonance (SR) during the descent of the Huygens Probe in the Titan's atmosphere on 14 January 2005. While Titan is staying inside the subsonic co-rotating magnetosphere of Saturn, a secondary magnetic field carrying an Extremely Low Frequency (ELF) modulation is shown to be generated through ion-acoustic instabilities of the Pedersen current sheets induced at the interface region between the impacting magnetospheric plasma and Titan's ionosphere. The stronger induced magnetic field components are focused within field-aligned arcs-like structures hanging down the current sheets, with minimum amplitude of about 0.3 nT throughout the ramside hemisphere from the ionopause down to the Moon surface, including the icy crust and its interface with a conductive water ocean. The deep penetration of the modulated magnetic field in the atmosphere is thought to be allowed thanks to the force balance between the average temporal variations of thermal and magnetic pressures within the field-aligned arcs. However, there is a first cause of diffusion of the ELF magnetic components, probably due to feeding one, or eventually several SR eigenmodes. A second leakage source is ascribed to a system of eddy-Foucault currents assumed to be induced through the buried water ocean. The amplitude spectrum distribution of the induced ELF magnetic field components inside the SR cavity is found fully consistent with the measurements of the Huygens wave-field strength. Waiting for expected future in-situ exploration of Titan's lower atmosphere and the surface, the Huygens data are the only experimental means available to date for constraining the proposed model.

  17. Magnetospheric structure and atmospheric Joule heating of habitable planets orbiting M-dwarf stars

    Energy Technology Data Exchange (ETDEWEB)

    Cohen, O.; Drake, J. J.; Garraffo, C.; Poppenhaeger, K. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Glocer, A. [NASA/GSFC, Code 673, Greenbelt, MD 20771 (United States); Bell, J. M. [Center for Planetary Atmospheres and Flight Sciences, National Institute of Aerospace, Hampton, VA 23666 (United States); Ridley, A. J.; Gombosi, T. I. [Center for Space Environment Modeling, University of Michigan, 2455 Hayward Street, Ann Arbor, MI 48109 (United States)

    2014-07-20

    We study the magnetospheric structure and the ionospheric Joule Heating of planets orbiting M-dwarf stars in the habitable zone using a set of magnetohydrodynamic models. The stellar wind solution is used to drive a model for the planetary magnetosphere, which is coupled with a model for the planetary ionosphere. Our simulations reveal that the space environment around close-in habitable planets is extreme, and the stellar wind plasma conditions change from sub- to super-Alfvénic along the planetary orbit. As a result, the magnetospheric structure changes dramatically with a bow shock forming in the super-Alfvénic sectors, while no bow shock forms in the sub-Alfvénic sectors. The planets reside most of the time in the sub-Alfvénic sectors with poor atmospheric protection. A significant amount of Joule Heating is provided at the top of the atmosphere as a result of the intense stellar wind. For the steady-state solution, the heating is about 0.1%-3% of the total incoming stellar irradiation, and it is enhanced by 50% for the time-dependent case. The significant Joule Heating obtained here should be considered in models for the atmospheres of habitable planets in terms of the thickness of the atmosphere, the top-side temperature and density, the boundary conditions for the atmospheric pressure, and particle radiation and transport. Here we assume constant ionospheric Pedersen conductance similar to that of the Earth. The conductance could be greater due to the intense EUV radiation leading to smaller heating rates. We plan to quantify the ionospheric conductance in future study.

  18. Duality of the magnetic flux tube and electric current descriptions magnetospheric plasma and energy flow

    International Nuclear Information System (INIS)

    Atkinson, G.

    1981-01-01

    The duality between electric current and magnetic flux tubes is outlined for the magnetosphere. Magnetic flux tubes are regarded as fluid elements subjected to various stresses. Current closure then becomes the dual of stress balance, and Poynting vector energy flow a dual of J x E dissipation. The stresses acting on a flux tube are magnetic stresses, which correspond to currents at a distance, and plasma stresses, which correspond to local currents. The duality between current and stress is traced for ionospheric ion drag forces, solar wind stresses at the magnetopause, inertial effects, and the effects of energetic plasma on flux tubes. The stress balance and dual current systems are outlined for idealized magnetospheres of increasing complexity. For a simple magnetosphere with no convective flow, the balance stresses are solar wind pressure and neutral sheet plasma pressure. The corresponding current systems are the Chapman-Ferraro magnetopause currents and the magetotail current system. The introduction of convective flow introduces further stresses: ionospheric ion drag. Alfven layer shielding, and an imbalance in day-night magnetic stresses due to transport of flux tubes to the nightside by the solar wind. These stresses balance, and hence the corresponding additional currents (the ionospheric Pedersen current and the electrojets, the partial ring current, and two other current systems from the magnetopause and tail) must form a closed current system and do so by the region I and II field-aligned currents of Iijima and Potemra. The energy flow in the above models is described in terms of both Poynting vectors and the above current systems. Temporal variations examined are (1) an increase in dayside merging and/or nightside reconnection, (2) an increase in the energy density of plasma in the plasma sheet, (3) an increase in ionospheric conductivity, and (4) an increase in solar wind pressure

  19. Semantic similarity measures in the biomedical domain by leveraging a web search engine.

    Science.gov (United States)

    Hsieh, Sheau-Ling; Chang, Wen-Yung; Chen, Chi-Huang; Weng, Yung-Ching

    2013-07-01

    Various researches in web related semantic similarity measures have been deployed. However, measuring semantic similarity between two terms remains a challenging task. The traditional ontology-based methodologies have a limitation that both concepts must be resided in the same ontology tree(s). Unfortunately, in practice, the assumption is not always applicable. On the other hand, if the corpus is sufficiently adequate, the corpus-based methodologies can overcome the limitation. Now, the web is a continuous and enormous growth corpus. Therefore, a method of estimating semantic similarity is proposed via exploiting the page counts of two biomedical concepts returned by Google AJAX web search engine. The features are extracted as the co-occurrence patterns of two given terms P and Q, by querying P, Q, as well as P AND Q, and the web search hit counts of the defined lexico-syntactic patterns. These similarity scores of different patterns are evaluated, by adapting support vector machines for classification, to leverage the robustness of semantic similarity measures. Experimental results validating against two datasets: dataset 1 provided by A. Hliaoutakis; dataset 2 provided by T. Pedersen, are presented and discussed. In dataset 1, the proposed approach achieves the best correlation coefficient (0.802) under SNOMED-CT. In dataset 2, the proposed method obtains the best correlation coefficient (SNOMED-CT: 0.705; MeSH: 0.723) with physician scores comparing with measures of other methods. However, the correlation coefficients (SNOMED-CT: 0.496; MeSH: 0.539) with coder scores received opposite outcomes. In conclusion, the semantic similarity findings of the proposed method are close to those of physicians' ratings. Furthermore, the study provides a cornerstone investigation for extracting fully relevant information from digitizing, free-text medical records in the National Taiwan University Hospital database.

  20. Local Geomagnetic Indices and the Prediction of Auroral Power

    Science.gov (United States)

    Newell, P. T.; Gjerloev, J. W.

    2014-12-01

    As the number of magnetometer stations and data processing power increases, just how auroral power relates to geomagnetic observations becomes a quantitatively more tractable question. This paper compares Polar UVI auroral power observations during 1997 with a variety of geomagnetic indices. Local time (LT) versions of the SuperMAG auroral electojet (SME) are introduced and examined, along with the corresponding upper and lower envelopes (SMU and SML). Also, the East-West component, BE, is investigated. We also consider whether using any of the local indices is actually better at predicting local auroral power than a single global index. Each index is separated into 24 LT indices based on a sliding 3-h MLT window. The ability to predict - or better reconstruct - auroral power varies greatly with LT, peaking at 1900 MLT, where about 75% of the variance (r2) can be predicted at 1-min cadence. The aurora is fairly predictable from 1700 MLT - 0400 MLT, roughly the region in which substorms occur. Auroral power is poorly predicted from auroral electrojet indices from 0500 MLT - 1500 MLT, with the minima at 1000-1300 MLT. In the region of high predictability, the local variable which works best is BE, in contrast to long-standing expectations. However using global SME is better than any local variable. Auroral power is best predicted by combining global SME with a local index: BE from 1500-0200 MLT, and either SMU or SML from 0300-1400 MLT. In the region of the diffuse aurora, it is better to use a 30 min average than the cotemporaneous 1-min SME value, while from 1500-0200 MLT the cotemporaneous 1-min SME works best, suggesting a more direct physical relationship with the auroral circuit. These results suggest a significant role for discrete auroral currents closing locally with Pedersen currents.

  1. A high-latitude, low-latitude boundary layer model of the convection current system

    International Nuclear Information System (INIS)

    Siscoe, G.L.; Lotko, W.; Sonnerup, B.U.O.

    1991-01-01

    Observations suggest that both the high- and low-latitude boundary layers contribute to magnetospheric convection, and that their contributions are linked. In the interpretation pursued here, the high-latitude boundary layer (HBL) generates the voltage while the low-latitude boundary layer (LBL) generates the current for the part of the convection electric circuit that closes through the ionosphere. This paper gives a model that joins the high- and low-latitude boundary layers consistently with the ionospheric Ohm's law. It describes an electric circuit linking both boundary layers, the region 1 Birkeland currents, and the ionospheric Pedersen closure currents. The model works by using the convection electric field that the ionosphere receives from the HBL to determine two boundary conditions to the equations that govern viscous LBL-ionosphere coupling. The result provides the needed self-consistent coupling between the two boundary layers and fully specifies the solution for the viscous LBL-ionosphere coupling equations. The solution shows that in providing the current required by the ionospheric Ohm's law, the LBL needs only a tenth of the voltage that spans the HBL. The solution also gives the latitude profiles of the ionospheric electric field, parallel currents, and parallel potential. It predicts that the plasma in the inner part of the LBL moves sunward instead of antisunward and that, as the transpolar potential decreases below about 40 kV, reverse polarity (region 0) currents appear at the poleward border of the region 1 currents. A possible problem with the model is its prediction of a thin boundary layer (∼1000 km), whereas thicknesses inferred from satellite data tend to be greater

  2. Striation formation associated with barium clouds in an inhomogeneous ionosphere

    International Nuclear Information System (INIS)

    Goldman, S.R.; Baker, L.; Ossakow, S.L.; Scannapieco, A.J.

    1976-01-01

    The present study investigates, via linear theory, how striations (treated as perturbations) created in a plasma cloud centered at 200 km will penetrate into the background inhomogeneous (real) ionosphere as a function of wavelength, integrated Pedersen conductivity ratio of the cloud to ionosphere (Σ/sub p/ /sub b//Σ/sub p/ /sub i/), and ambient ionospheric conditions. The study is posed as an eigenvalue problem which, while determining the potential variation (eigenmode) along magnetic field lines, self-consistently solves for the growth rate (eigenvalue) in the coupled cloud-inhomogeneous ionosphere system. Perturbed particle densities, fluxes parallel to the magnetic field B, and electrostatic potential are presented as a function of altitude. The results show the importance of the transport parameter the magnitude of imaging and aspect angle of striations with respect to B (i.e., striations take on a parallel component of wave number). Our results show that clouds with smaller conductivity ratios produce image striations further down into the background E region ionosphere with a more uniform coupling as a function of wavelength. It is further shown that there is a slight dependence of the E region coupling of the perturbations on the level of solar activity (solar maximum or minimum conditions) and also that this E region coupling shows a slight dependence on the extent of F region coupling above the cloud. Finally, with a fully self-consistent treatment of F region coupling, the growth rates show negligible short-wavelength damping due to ionospheric coupling for the Σ/sub p/ /sub b//Σ/sub p/ /sub i/=4 case

  3. Reliability of performance velocity for jump squats under feedback and nonfeedback conditions.

    Science.gov (United States)

    Randell, Aaron D; Cronin, John B; Keogh, Justin Wl; Gill, Nicholas D; Pedersen, Murray C

    2011-12-01

    Randell, AD, Cronin, JB, Keogh, JWL, Gill, ND, and Pedersen, MC. Reliability of performance velocity for jump squats under feedback and nonfeedback conditions. J Strength Cond Res 25(12): 3514-3518, 2011-Advancements in the monitoring of kinematic and kinetic variables during resistance training have resulted in the ability to continuously monitor performance and provide feedback during training. If equipment and software can provide reliable instantaneous feedback related to the variable of interest during training, it is thought that this may result in goal-oriented movement tasks that increase the likelihood of transference to on-field performance or at the very least improve the mechanical variable of interest. The purpose of this study was to determine the reliability of performance velocity for jump squats under feedback and nonfeedback conditions over 3 consecutive training sessions. Twenty subjects were randomly allocated to a feedback or nonfeedback group, and each group performed a total of 3 "jump squat" training sessions with the velocity of each repetition measured using a linear position transducer. There was less change in mean velocities between sessions 1-2 and sessions 2-3 (0.07 and 0.02 vs. 0.13 and -0.04 m·s), less random variation (TE = 0.06 and 0.06 vs. 0.10 and 0.07 m·s) and greater consistency (intraclass correlation coefficient = 0.83 and 0.87 vs. 0.53 and 0.74) between sessions for the feedback condition as compared to the nonfeedback condition. It was concluded that there is approximately a 50-50 probability that the provision of feedback was beneficial to the performance in the squat jump over multiple sessions. It is suggested that this has the potential for increasing transference to on-field performance or at the very least improving the mechanical variable of interest.

  4. Electrodynamics properties of auroral surges

    International Nuclear Information System (INIS)

    Robinson, R.M.; Vondrak, R.R.

    1990-01-01

    The incoherent scatter radar technique provides an excellent means to study the ionization and electric fields associated with auroral precipitation events. One of the most intense and dynamic auroral events is the so-called surge or breakup aurora that accompanies auroral substorms. For their purposes they define a surge as a transient intensification of auroral precipitation that occurs simultaneously with a pronounced negative bay in the ground magnetometer data. They present data obtained during five such events in 1980 and 1981. Prior to the surge, auroral forms move equatorward, develop ray structure, and intensify. The surge is identified by an apparent poleward motion of the aurora producing aurorally associated ionization that extends over several hundred kilometers in latitude. The presurge auroral forms are embedded in a region of northward electric field. The auroral forms that comprise the surge span a region within which the meridional electric field is small and at times southward. A westward electric field is often but not always present within the surge. The behavior of the westward electric field is significantly different from the north-south field, in that sharp spatial gradients are absent even in very disturbed conditions. Although the westward Hall currents are mostly responsible for the negative bays that accompany the surge, at times the westward Pedersen current sustained by the westward electric field can be important. Sudden variations in the H component of the ground magnetogram can be caused by motions of the aurora or by temporal variations in the fields or conductivities. They present a model that simulates the observed changes in electric field and precipitation that accompany surges. The perturbation in the electric field produced by the surge is simulated by adding negative potential in regions of intense precipitation

  5. Coupled storm-time magnetosphere-ionosphere-thermosphere simulations including microscopic ionospheric turbulence

    Science.gov (United States)

    Merkin, V. G.; Wiltberger, M. J.; Zhang, B.; Liu, J.; Wang, W.; Dimant, Y. S.; Oppenheim, M. M.; Lyon, J.

    2017-12-01

    During geomagnetic storms the magnetosphere-ionosphere-thermosphere system becomes activated in ways that are unique to disturbed conditions. This leads to emergence of physical feedback loops that provide tighter coupling between the system elements, often operating across disparate spatial and temporal scales. One such process that has recently received renewed interest is the generation of microscopic ionospheric turbulence in the electrojet regions (electrojet turbulence, ET) that results from strong convective electric fields imposed by the solar wind-magnetosphere interaction. ET leads to anomalous electron heating and generation of non-linear Pedersen current - both of which result in significant increases in effective ionospheric conductances. This, in turn, provides strong non-linear feedback on the magnetosphere. Recently, our group has published two studies aiming at a comprehensive analysis of the global effects of this microscopic process on the magnetosphere-ionosphere-thermosphere system. In one study, ET physics was incorporated in the TIEGCM model of the ionosphere-thermosphere. In the other study, ad hoc corrections to the ionospheric conductances based on ET theory were incorporated in the conductance module of the Lyon-Fedder-Mobarry (LFM) global magnetosphere model. In this presentation, we make the final step toward the full coupling of the microscopic ET physics within our global coupled model including LFM, the Rice Convection Model (RCM) and TIEGCM. To this end, ET effects are incorporated in the TIEGCM model and propagate throughout the system via thus modified TIEGCM conductances. The March 17, 2013 geomagnetic storm is used as a testbed for these fully coupled simulations, and the results of the model are compared with various ionospheric and magnetospheric observatories, including DMSP, AMPERE, and Van Allen Probes. Via these comparisons, we investigate, in particular, the ET effects on the global magnetosphere indicators such as the

  6. Medical databases in studies of drug teratogenicity: methodological issues

    Directory of Open Access Journals (Sweden)

    Vera Ehrenstein

    2010-03-01

    Full Text Available Vera Ehrenstein1, Henrik T Sørensen1, Leiv S Bakketeig1,2, Lars Pedersen11Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark; 2Norwegian Institute of Public Health, Oslo, NorwayAbstract: More than half of all pregnant women take prescription medications, raising concerns about fetal safety. Medical databases routinely collecting data from large populations are potentially valuable resources for cohort studies addressing teratogenicity of drugs. These include electronic medical records, administrative databases, population health registries, and teratogenicity information services. Medical databases allow estimation of prevalences of birth defects with enhanced precision, but systematic error remains a potentially serious problem. In this review, we first provide a brief description of types of North American and European medical databases suitable for studying teratogenicity of drugs and then discuss manifestation of systematic errors in teratogenicity studies based on such databases. Selection bias stems primarily from the inability to ascertain all reproductive outcomes. Information bias (misclassification may be caused by paucity of recorded clinical details or incomplete documentation of medication use. Confounding, particularly confounding by indication, can rarely be ruled out. Bias that either masks teratogenicity or creates false appearance thereof, may have adverse consequences for the health of the child and the mother. Biases should be quantified and their potential impact on the study results should be assessed. Both theory and software are available for such estimation. Provided that methodological problems are understood and effectively handled, computerized medical databases are a valuable source of data for studies of teratogenicity of drugs.Keywords: databases, birth defects, epidemiologic methods, pharmacoepidemiology

  7. Development of a Web-Based Health Care Intervention for Patients With Heart Disease: Lessons Learned From a Participatory Design Study.

    Science.gov (United States)

    Noergaard, Birgitte; Sandvei, Marianne; Rottmann, Nina; Johannessen, Helle; Wiil, Uffe; Schmidt, Thomas; Pedersen, Susanne S

    2017-05-17

    The use of telemedicine technologies in health care has increased substantially, together with a growing interest in participatory design methods when developing telemedicine approaches. We present lessons learned from a case study involving patients with heart disease and health care professionals in the development of a personalized Web-based health care intervention. We used a participatory design approach inspired by the method for feasibility studies in software development. We collected qualitative data using multiple methods in 3 workshops and analyzed the data using thematic analysis. Participants were 7 patients with diagnosis of heart disease, 2 nurses, 1 physician, 2 systems architects, 3 moderators, and 3 observers. We present findings in 2 parts. (1) Outcomes of the participatory design process: users gave valuable feedback on ease of use of the platforms' tracking tools, platform design, terminology, and insights into patients' monitoring needs, information and communication technologies skills, and preferences for self-management tools. (2) Experiences from the participatory design process: patients and health care professionals contributed different perspectives, with the patients using an experience-based approach and the health care professionals using a more attitude-based approach. The essential lessons learned concern planning and organization of workshops, including the finding that patients engaged actively and willingly in a participatory design process, whereas it was more challenging to include and engage health care professionals. ©Birgitte Noergaard, Marianne Sandvei, Nina Rottmann, Helle Johannessen, Uffe Wiil, Thomas Schmidt, Susanne S Pedersen. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 17.05.2017.

  8. Poynting flux measurements on a satellite: A diagnostic tool for space research

    International Nuclear Information System (INIS)

    Kelley, M.C.; Knudsen, D.J.; Vickery, J.F.

    1991-01-01

    The first satellite observations of the total field-aligned component of the quasi-dc Poynting flux are presented for two passes over the polar region, one in the noon sector and one in the afternoon. The energy input due to electron precipitation is also presented. In the noon pass the downward Poynting flux in the auroral oval was comparable to the kinetic energy input rate. The peak electromagnetic energy input rate of 6 ergs/(cm 2 s) equaled the peak particle input while the integrated electromagnetic value along the trajectory was 60% that of the particles. In the afternoon pass the peak electromagnetic energy input was also about 6 ergs/(cm 2 s), but the peak particle energy was 6 times this value. The average electromagnetic input was 10% of the particle input for the pass. In this study, the authors can measure the Poynting flux only over a limited range of scale sizes; thus the contribution to the total energy budget in the polar cap cannot be determined. Both passes show small regions characterized by upward Poynting flux suggesting a neutral wind dynamo. There is also evidence during part of the noontime pass that the external generator acted in opposition to an existing wind field since the Poynting flux was greater than the estimate of Joule heating from the electric field measurement alone (i.e., from Σ p E 2 ). In the course of deriving Poynting's theorem for the geophysical case they also present a proof that ground magnetometer systems respond primarily to the Hall current which does not depend upon geometric cancellation between the field generated by Pedersen and field-aligned currents

  9. The Danish Sarcoma Database

    Directory of Open Access Journals (Sweden)

    Jorgensen PH

    2016-10-01

    Full Text Available Peter Holmberg Jørgensen,1 Gunnar Schwarz Lausten,2 Alma B Pedersen3 1Tumor Section, Department of Orthopedic Surgery, Aarhus University Hospital, Aarhus, 2Tumor Section, Department of Orthopedic Surgery, Rigshospitalet, Copenhagen, 3Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark Aim: The aim of the database is to gather information about sarcomas treated in Denmark in order to continuously monitor and improve the quality of sarcoma treatment in a local, a national, and an international perspective. Study population: Patients in Denmark diagnosed with a sarcoma, both skeletal and ekstraskeletal, are to be registered since 2009. Main variables: The database contains information about appearance of symptoms; date of receiving referral to a sarcoma center; date of first visit; whether surgery has been performed elsewhere before referral, diagnosis, and treatment; tumor characteristics such as location, size, malignancy grade, and growth pattern; details on treatment (kind of surgery, amount of radiation therapy, type and duration of chemotherapy; complications of treatment; local recurrence and metastases; and comorbidity. In addition, several quality indicators are registered in order to measure the quality of care provided by the hospitals and make comparisons between hospitals and with international standards. Descriptive data: Demographic patient-specific data such as age, sex, region of living, comorbidity, World Health Organization's International Classification of Diseases – tenth edition codes and TNM Classification of Malignant Tumours, and date of death (after yearly coupling to the Danish Civil Registration System. Data quality and completeness are currently secured. Conclusion: The Danish Sarcoma Database is population based and includes sarcomas occurring in Denmark since 2009. It is a valuable tool for monitoring sarcoma incidence and quality of treatment and its improvement, postoperative

  10. Comparative digital cartilage histology for human and common osteoarthritis models

    Directory of Open Access Journals (Sweden)

    Pedersen DR

    2013-02-01

    Full Text Available Douglas R Pedersen, Jessica E Goetz, Gail L Kurriger, James A MartinDepartment of Orthopaedics and Rehabilitation, University of Iowa, Iowa City, IA, USAPurpose: This study addresses the species-specific and site-specific details of weight-bearing articular cartilage zone depths and chondrocyte distributions among humans and common osteoarthritis (OA animal models using contemporary digital imaging tools. Histological analysis is the gold-standard research tool for evaluating cartilage health, OA severity, and treatment efficacy. Historically, evaluations were made by expert analysts. However, state-of-the-art tools have been developed that allow for digitization of entire histological sections for computer-aided analysis. Large volumes of common digital cartilage metrics directly complement elucidation of trends in OA inducement and concomitant potential treatments.Materials and methods: Sixteen fresh human knees, 26 adult New Zealand rabbit stifles, and 104 bovine lateral plateaus were measured for four cartilage zones and the cell densities within each zone. Each knee was divided into four weight-bearing sites: the medial and lateral plateaus and femoral condyles.Results: One-way analysis of variance followed by pairwise multiple comparisons (Holm–Sidak method at a significance of 0.05 clearly confirmed the variability between cartilage depths at each site, between sites in the same species, and between weight-bearing articular cartilage definitions in different species.Conclusion: The present study clearly demonstrates multisite, multispecies differences in normal weight-bearing articular cartilage, which can be objectively quantified by a common digital histology imaging technique. The clear site-specific differences in normal cartilage must be taken into consideration when characterizing the pathoetiology of OA models. Together, these provide a path to consistently analyze the volume and variety of histologic slides necessarily generated

  11. Hepatitis C virus infection and risk of cancer: a population-based cohort study

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    Lars Haukali Omland

    2010-06-01

    Full Text Available Lars Haukali Omland1, Dora Körmendiné Farkas2, Peter Jepsen2,3, Niels Obel1, Lars Pedersen21Department of Infectious Diseases, Rigshospitalet, Denmark; 2Department of Clinical Epidemiology, 3Department of Medicine V (Hepatology and Gastroenterology, Aarhus University Hospital, DenmarkBackground: Hepatitis C virus (HCV infection is associated with an increased risk of primary liver cancer; however, 5- and 10-year risk estimates are needed. The association of HCV with non-Hodgkin lymphoma (NHL is uncertain and the association with other cancers is unknown.Method: We conducted a nationwide, population-based cohort study of 4,349 HCV-infected patients in Denmark, computing standardized incidence ratios (SIR of cancer incidence in HCV infected patients compared with cancer incidence of the general population. We calculated 5-and 10-year risks of developing cancer, stratifying our analyses based on the presence of HIV coinfection and cirrhosis.Results: We recorded an increased risk of primary liver cancer (SIR: 76.63 [95% CI: 51.69–109.40], NHL (SIR: 1.89 [95% CI: 0.39–5.52], and several smoking- and alcohol-related cancers in HCV infected patients without HIV coinfection. HCV-infected patients without HIV coinfection had a 6.3% (95% CI: 4.6%–8.7% risk of developing cancer and 2.0% (95% CI: 1.1%–3.8% risk of developing primary liver cancer within 10 years.Conclusion: We confirmed the association of HCV infection with primary liver cancer and NHL. We also observed an association between HCV infection and alcohol- and smoking-related cancers.Keywords: hepatitis C virus, non-Hodgkin lymphoma, standardized incidence ratio, cancer

  12. Sottotitolazione intralinguistica e inglese ‘lingua franca’: strategie di mediazione audiovisiva

    Directory of Open Access Journals (Sweden)

    Pietro Luigi Iaia

    2016-01-01

    Full Text Available Abstract – This chapter illustrates the results of a workshop held at the University of Salento, during an English-Italian Translation Course. A group of undergraduate students was asked to produce an intralingual translation for the subtitles of the video Capsized in Lampedusa – Fortress Italia, which deals with the situation in Lampedusa after a boat capsized in October 2013. The original video – available on YouTube – is subtitled into English for Vice News and, in a ‘role play’ exercise (Rosnow 1990, students were commissioned to adopt a type of English that could be directed at a wider international audience also including non-native English speakers. The contrastive analysis of the original and reformulated versions is designed to enquire into the influence and actualisation of the commissioner’s requests in the lexical, structural and functional features of target texts. The extent will also be explored, to which the type of English adopted in the alternative subtitles can be defined as a lingua-franca variation (Seidlhofer 2011, due to the inclusion of specific verb tenses and the selection of simplified syntactic structures (Seidlhofer 2004, aimed at facilitating the audience’s reception and accessibility to the semantic dimensions of the text. Finally, the analysis will also highlight the translators’ attempts to respect the temporal and spatial constraints of subtitles (Neves 2009, as well as the multimodal construction (Kress and van Leeuwen 2006 of audiovisual texts, which result in the use of condensation strategies (Gottlieb 2005; Pedersen 2011, thus proposing the new definition of audiovisual mediation.

  13. The electrodynamic, thermal, and energetic character of intense sun-aligned arcs in the polar cap

    International Nuclear Information System (INIS)

    Valladares, C.E.; Carlson, H.C. Jr.

    1991-01-01

    The authors report here measurements of two intense Sun-aligned arcs. The two arcs were diagnosed on two different nights (February 26 and March 1, 1987) using the Sondre Stromfjord radar as a stand-alone diagnostic. Repeatable patterns are found in mesoscale area (order 10 3 km by 10 3 km) maps of altitude profiles for observed electron and ion gas number densities, temperatures and line-of-sight velocities, and projected mesoscale area maps of derived electric fields, Pedersen and Hall conductivities (N e , T e , T i , V, E, Σ p , Σ H ), horizontal and field-aligned currents, joule heating rate, and Poynting flux. They confirm, for the first time with continuous mesoscale area maps, that the arcs have the anticipated simple arc electrodynamics. That is, the visual and enhanced ionization signatures of the arc are produced by incoming energetic electrons carrying the outgoing current from the electric field convergence in the arc. Strong electron temperature enhancements (>2,000 K) are found as expected within the sheets of ionizing particle precipitation. Dawn to dusk decreases in the antisunward plasma flow of order 1 km s -1 , across order 100 km, correspond to peak electron densities of order 10 5 cm -3 down to altitudes as low as 120 km, and upward currents of order 1 μA m -2 . These data also lead to important implications for the physics of polar cap arcs. The high-velocity (antisunward flow on the dawnside) edge of the arc marks the location of strong persistent Joule heating driven by downward Poynting flux. The deposition rate into the atmosphere of the net electromagnetic energy well exceeds the net particle energy deposited by the ionizing energetic electron flux. This heating is a substantial source of heat into the polar thermosphere

  14. Theoretical and experimental zonal drift velocities of the ionospheric plasma bubbles over the Brazilian region

    Science.gov (United States)

    Arruda, Daniela C. S.; Sobral, J. H. A.; Abdu, M. A.; Castilho, Vivian M.; Takahashi, H.; Medeiros, A. F.; Buriti, R. A.

    2006-01-01

    This work presents equatorial ionospheric plasma bubble zonal drift velocity observations and their comparison with model calculations. The bubble zonal velocities were measured using airglow OI630 nm all-sky digital images and the model calculations were performed taking into account flux-tube integrated Pedersen conductivity and conductivity weighted neutral zonal winds. The digital images were obtained from an all-sky imaging system operated over the low-latitude station Cachoeira Paulista (Geogr. 22.5S, 45W, dip angle 31.5S) during the period from October 1998 to August 2000. Out of the 138 nights of imager observation, 29 nights with the presence of plasma bubbles are used in this study. These 29 nights correspond to geomagnetically rather quiet days (∑K P hours, the calculated zonal drift velocities were found to be larger than the experimental values. The best matching between the calculated and observed zonal velocities were seen to be for a few hours around midnight. The model calculation showed two humps around 20 LT and 24 LT that were not present in the data. Average decelerations obtained from linear regression between 20 LT and 24 LT were found to be: (a) Spring 1998, -8.61 ms -1 h -1; (b) Summer 1999, -0.59 ms -1 h -1; (c) Spring 1999, -11.72 ms -1 h -1; and (d) Summer 2000, -8.59 ms -1 h -1. Notice that Summer and Winter here correspond to southern hemisphere Summer and Winter, not northern hemisphere.

  15. Clinical, virological and immunological responses in Danish HIV patients receiving raltegravir as part of a salvage regimen

    Directory of Open Access Journals (Sweden)

    Frederik N Engsig

    2010-05-01

    Full Text Available Frederik N Engsig1, Jan Gerstoft1, Gitte Kronborg2, Carsten S Larsen3, Gitte Pedersen4, Anne M Audelin5, Louise B Jørgensen5, Niels Obel11Department of Infectious Diseases, Copenhagen University Hospital, Rigshospitalet, Denmark; 2Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark; 3Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark; 4Department of Infectious Diseases, Aalborg University Hospital, Aalborg, Denmark; 5Department of Virology, Statens Serum Institute, Copenhagen, DenmarkBackground: Raltegravir is the first integrase inhibitor approved for treatment of HIV-infected patients harboring multiresistant viruses.Methods: From a Danish population-based nationwide cohort of HIV patients we identified the individuals who initiated a salvage regimen including raltegravir and a matched cohort of HIV-infected patients initiating HAART for the first time. We compared these two cohorts for virological suppression, gain in CD4 count, and time to first change of initial regimen.Results: We identified 32 raltegravir patients and 64 HIV patients who initiated HAART for the first time in the period 1 January 2006 to 1 July 2009. The virological and immunological responses in the raltegravir patients were comparable to those seen in the control cohort. No patients in the two cohorts died and no patients terminated raltegravir treatment in the observation period. Time to first change of initial regimen was considerably shorter for HAART-naïve patients.Conclusion: We conclude that salvage regimens including raltegravir have high effectiveness in the everyday clinical setting. The effectiveness of the regimens is comparable to that observed for patients initiating HAART for the first time. The risk of change in the salvage regimens after initiation of raltegravir is low.Keywords: HIV, raltegravir, salvage regime, efficacy, matched cohort

  16. Direct evidence of plasma - density structuring in the auroral F-region ionosphere

    International Nuclear Information System (INIS)

    Tsunoda, R.T.; Haeggstroem, I.; Pellinen-Wannberg, A.; Steen, Aa.; Wannberg, G.

    1985-03-01

    We investigate the hypothesis that large-scale plasma-density enhancements found in the auroral F layer become structured via a magnetic-flux-tube interchange (MFTI) process. In such a process, plasma structure is produced when spatially irregular electric fields transport higher number-density plasma into a region containing lower number-density plasma, and vice versa. Direct experimental evidence of this process can be obtained by measuring concurrently the spatial distributions of F-region plasma density and electric field. Using the tristatic EISCAT radar facility, we measured these quantities in a two-dimensional plane transverse to the geomagnetic field, at 300-km altitude. We show, in a case study, that plasma-density structure found along the poleward wall of a blob was indeed accompanied by similar-scale variations in the ionospheric electric field, and that the sense of relative motion between high- and low-number-density plasma is consistent with ongoing structuring of the plasma via a MFTI process. From the estimated growth rate of 3 x 10 -3 s -1 , the observed plasma structure could have been produced in several minutes by the irregular electic field pattern. The source of the MFTI process, however, is not clear. The MFTI process did not appear to be driven by F-region polarization electric fields, a conclusion based on (1) the apparent lack of inverse correlation between plasma density and 'slip' velocity patterns, and (2) the positive growth rate found along the poleward wall of the blob in the presence of a westward Pedersen current. This conclusion excludes (at least for this data set) the gradient-drift and current-convective instabilities as primary sources of the ongoing structuring process. (Author)

  17. NovoPen Echo® insulin delivery device

    Directory of Open Access Journals (Sweden)

    Hyllested-Winge J

    2016-01-01

    Full Text Available Jacob Hyllested-Winge,1 Thomas Sparre,2 Line Kynemund Pedersen2 1Novo Nordisk Pharma Ltd, Tokyo, Japan; 2Novo Nordisk A/S, Søborg, Denmark Abstract: The introduction of insulin pen devices has provided easier, well-tolerated, and more convenient treatment regimens for patients with diabetes mellitus. When compared with vial and syringe regimens, insulin pens offer a greater clinical efficacy, improved quality of life, and increased dosing accuracy, particularly at low doses. The portable and discreet nature of pen devices reduces the burden on the patient, facilitates adherence, and subsequently contributes to the improvement in glycemic control. NovoPen Echo® is one of the latest members of the NovoPen® family that has been specifically designed for the pediatric population and is the first to combine half-unit increment (=0.5 U of insulin dosing with a simple memory function. The half-unit increment dosing amendments and accurate injection of 0.5 U of insulin are particularly beneficial for children (and insulin-sensitive adults/elders, who often require small insulin doses. The memory function can be used to record the time and amount of the last dose, reducing the fear of double dosing or missing a dose. The memory function also provides parents with extra confidence and security that their child is taking insulin at the correct doses and times. NovoPen Echo is a lightweight, durable insulin delivery pen; it is available in two different colors, which may help to distinguish between different types of insulin, providing more confidence for both users and caregivers. Studies have demonstrated a high level of patient satisfaction, with 80% of users preferring NovoPen Echo to other pediatric insulin pens. Keywords: NovoPen Echo®, memory function, half-unit increment dosing, adherence, children, adolescents 

  18. Enhanced understanding of ectoparasite: host trophic linkages on coral reefs through stable isotope analysis

    Science.gov (United States)

    Demopoulos, Amanda W. J.; Sikkel, Paul C.

    2015-01-01

    Parasitism, although the most common type of ecological interaction, is usually ignored in food web models and studies of trophic connectivity. Stable isotope analysis is widely used in assessing the flow of energy in ecological communities and thus is a potentially valuable tool in understanding the cryptic trophic relationships mediated by parasites. In an effort to assess the utility of stable isotope analysis in understanding the role of parasites in complex coral-reef trophic systems, we performed stable isotope analysis on three common Caribbean reef fish hosts and two kinds of ectoparasitic isopods: temporarily parasitic gnathiids (Gnathia marleyi) and permanently parasitic cymothoids (Anilocra). To further track the transfer of fish-derived carbon (energy) from parasites to parasite consumers, gnathiids from host fish were also fed to captive Pederson shrimp (Ancylomenes pedersoni) for at least 1 month. Parasitic isopods had δ13C and δ15N values similar to their host, comparable with results from the small number of other host–parasite studies that have employed stable isotopes. Adult gnathiids were enriched in 15N and depleted in13C relative to juvenile gnathiids, providing insights into the potential isotopic fractionation associated with blood-meal assimilation and subsequent metamorphosis. Gnathiid-fed Pedersen shrimp also had δ13C values consistent with their food source and enriched in 15N as predicted due to trophic fractionation. These results further indicate that stable isotopes can be an effective tool in deciphering cryptic feeding relationships involving parasites and their consumers, and the role of parasites and cleaners in carbon transfer in coral-reef ecosystems specifically.

  19. Shear Alfven Wave Injection in the Magnetosphere by Ionospheric Modifications in the Absence of Electrojet Currents

    Science.gov (United States)

    Papadopoulos, K.; Eliasson, B.; Shao, X.; Labenski, J.; Chang, C.

    2011-12-01

    A new concept of generating ionospheric currents in the ULF/ELF range with modulated HF heating using ground-based transmitters even in the absence of electrojet currents is presented. The new concept relies on using HF heating of the F-region to modulate the electron temperature and has been given the name Ionospheric Current Drive (ICD). In ICD, the pressure gradient associated with anomalous or collisional F-region electron heating drives a local diamagnetic current that acts as an antenna to inject mainly Magneto-Sonic (MS) waves in the ionospheric plasma. The electric field associated with the MS wave drives Hall currents when it reaches the E region of the ionosphere. The Hall currents act as a secondary antenna that inject waves in the Earth-Ionosphere Waveguide (EIW) below and shear Alfven waves or EMIC waves upwards towards the conjugate regions. The paper presents: (i) Theoretical results using a cold Hall MHD model to study ICD and the generation of ULF/ELF waves by the modulation of the electron pressure at the F2-region with an intense HF electromagnetic wave. The model solves equations governing the dynamics of the shear Alfven and magnetosonic modes, of the damped modes in the diffusive Pedersen layer, and of the weakly damped helicon wave mode in the Hall-dominated E-region. The model incorporates realistic profile of the ionospheric conductivities and magnetic field configuration. We use the model to simulate propagation and dynamics of the low-frequency waves and their injection into the magnetosphere from the HAARP and Arecibo ionospheric heaters. (ii) Proof of principle experiments using the HAARP ionospheric heater in conjunction with measurements by the DEMETER satellite This work is supported by ONR MURI grant and DARPA BRIOCHE Program

  20. Coordinated observations of postmidnight irregularities and thermospheric neutral winds and temperatures at low latitudes

    Science.gov (United States)

    Dao, Tam; Otsuka, Yuichi; Shiokawa, Kazuo; Nishioka, Michi; Yamamoto, Mamoru; Buhari, Suhaila M.; Abdullah, Mardina; Husin, Asnawi

    2017-07-01

    We investigated a postmidnight field-aligned irregularity (FAI) event observed with the Equatorial Atmosphere Radar at Kototabang (0.2°S, 100.3°E, dip latitude 10.4°S) in Indonesia on the night of 9 July 2010 using a comprehensive data set of both neutral and plasma parameters. We examined the rate of total electron content change index (ROTI) obtained from GPS receivers in Southeast Asia, airglow images detected by an all-sky imager, and thermospheric neutral winds and temperatures obtained by a Fabry-Perot interferometer at Kototabang. Altitudes of the F layer (h'F) observed by ionosondes at Kototabang, Chiang Mai, and Chumphon were also surveyed. We found that the postmidnight FAIs occurred within plasma bubbles and coincided with kilometer-scale plasma density irregularities. We also observed an enhancement of the magnetically equatorward thermospheric neutral wind at the same time as the increase of h'F at low-latitude stations, but h'F at a station near the magnetic equator remained invariant. Simultaneously, a magnetically equatorward gradient of thermospheric temperature was identified at Kototabang. The convergence of equatorward neutral winds from the Northern and Southern Hemispheres could be associated with a midnight temperature maximum occurring around the magnetic equator. Equatorward neutral winds can uplift the F layer at low latitudes and increase the growth rate of Rayleigh-Taylor instabilities, causing more rapid extension of plasma bubbles. The equatorward winds in both hemispheres also intensify the eastward Pedersen current, so a large polarization electric field generated in the plasma bubble might play an important role in the generation of postmidnight FAIs.

  1. Sub-corotating region of Saturn's magnetosphere: Cassini observations of the azimuthal field and implications for the ionospheric Pederesen Current (Invited)

    Science.gov (United States)

    Smith, E. J.; Dougherty, M. K.; Zhou, X.

    2010-12-01

    A consensus model of Saturn’s magnetosphere that has broad acceptance consists of four regions in which the plasma and field are corotating, sub-corotating or undergoing Vasyliunas or Dungey convection. In this model, the sub-corotating magnetosphere contains a large scale circuital current system comprised of radial, field-aligned and ionospheric currents. A quantitative rendering of this system developed by S. Cowley and E. Bunch relates the azimuthal field component, B phi, that causes the field to spiral to the ionospheric Pedersen current , Ip. Cassini measurements of B phi over the four year interval between 2005 and 2008 that are widely distributed in radial distance, latitude and local time have been used to compute Ip from a Bunce-Cowley formula. A striking north-south asymmetry of the global magnetosphere has been found. In the southern hemisphere, the magnitude and variation of Ip with invariant colatitude, θ, agree qualitatively with the model but Ip (θ) is shifted poleward by about 10°. In the northern hemisphere, however, the data fail to reproduce the profile of Ip (θ) predicted by the model but are dominated by two high latitude currents having the wrong polarities. Possible causes of this asymmetry are seasonal variations (summer in the southern hemisphere) and/or asymmetric plasma outflow from the inner magnetosphere such as the plumes extending southward from Enceladus. Another finding is a significant local time dependence of Ip(θ) rather than the axisymmetry assumed in the model. There is a close correspondence with the model in the noon sector. The currents in the midnight and dawn sectors are significantly larger than in the noon sector and the current in the dusk sector is dramatically weaker.

  2. Strange VLF bursts in northern Scandinavia: case study of the afternoon "mushroom-like" hiss on 8 December 2013

    Directory of Open Access Journals (Sweden)

    J. Manninen

    2015-08-01

    Full Text Available We investigate a non-typical very low frequency (VLF 1–4 kHz hiss representing a sequence of separated noise bursts with a strange "mushroom-like" shape in the frequency–time domain, each one lasting several minutes. These strange afternoon VLF emissions were recorded at Kannuslehto (KAN, ϕ = 67.74° N, λ = 26.27° E; L ∼ 5.5 in northern Finland during the late recovery phase of the small magnetic storm on 8 December 2013. The left-hand (LH polarized 2–3 kHz "mushroom caps" were clearly separated from the right-hand (RH polarized "mushroom stems" at the frequency of about 1.8–1.9 kHz, which could match the lower ionosphere waveguide cutoff (the first transverse resonance of the Earth–ionosphere cavity. We hypothesize that this VLF burst sequence could be a result of the modulation of the VLF hiss electron–cyclotron instability from the strong Pc5 geomagnetic pulsations observed simultaneously at ground-based stations as well as in the inner magnetosphere by the Time History of Events and Macroscale Interactions during Substorms mission probe (THEMIS-E; ThE. This assumption is confirmed by a similar modulation of the intensity of the energetic (1–10 keV electrons simultaneously observed by the same ThE spacecraft. In addition, the data of the European Incoherent Scatter Scientific Association (EISCAT radar at Tromsø show a similar quasi-periodicity in the ratio of the Hall-to-Pedersen conductance, which may be used as a proxy for the energetic particle precipitation enhancement. Our findings suggest that this strange mushroom-like shape of the considered VLF hiss could be a combined mutual effect of the magnetospheric ULF–VLF (ultra low frequency–very low frequency wave interaction and the ionosphere waveguide propagation.

  3. Enhanced understanding of ectoparasite–host trophic linkages on coral reefs through stable isotope analysis

    Directory of Open Access Journals (Sweden)

    Amanda W.J. Demopoulos

    2015-04-01

    Full Text Available Parasitism, although the most common type of ecological interaction, is usually ignored in food web models and studies of trophic connectivity. Stable isotope analysis is widely used in assessing the flow of energy in ecological communities and thus is a potentially valuable tool in understanding the cryptic trophic relationships mediated by parasites. In an effort to assess the utility of stable isotope analysis in understanding the role of parasites in complex coral-reef trophic systems, we performed stable isotope analysis on three common Caribbean reef fish hosts and two kinds of ectoparasitic isopods: temporarily parasitic gnathiids (Gnathia marleyi and permanently parasitic cymothoids (Anilocra. To further track the transfer of fish-derived carbon (energy from parasites to parasite consumers, gnathiids from host fish were also fed to captive Pederson shrimp (Ancylomenes pedersoni for at least 1 month. Parasitic isopods had δ13C and δ15N values similar to their host, comparable with results from the small number of other host–parasite studies that have employed stable isotopes. Adult gnathiids were enriched in 15N and depleted in 13C relative to juvenile gnathiids, providing insights into the potential isotopic fractionation associated with blood-meal assimilation and subsequent metamorphosis. Gnathiid-fed Pedersen shrimp also had δ13C values consistent with their food source and enriched in 15N as predicted due to trophic fractionation. These results further indicate that stable isotopes can be an effective tool in deciphering cryptic feeding relationships involving parasites and their consumers, and the role of parasites and cleaners in carbon transfer in coral-reef ecosystems specifically.

  4. Global snowline and mountain topography: a contrasted view

    Science.gov (United States)

    Champagnac, Jean-Daniel; Herman, Frédéric; Valla, Pierre

    2013-04-01

    ~40 and ~60° (or between ELA of ~500m to ~2500m a.s.l.). This mid-latitude relatively greater relief challenges the straightforward relationship between glaciations, erosion and topography. Oppositely, it suggests that glacier may be more efficient agent in temperate area, with an important amplitude between glacial and interglacial climate. This is consistent with the view of a very variable glacier erodibility that can erode and protect the landscape, as well as with studies documenting a bimodal location of the preferred glacial erosion, at relatively high elevation (around the long-term ELA), and at much lower elevation (close to the glacial maximum lower reaches), thanks to efficient water lubrication of the glacier bases that greatly enhance the sliding velocity (Herman et al., 2011). These findings show that the relation between the mountain topography and the long term snowline is not as straightforward as previously proposed (e.g. Egholm et al., 2009) . Beside the role of tectonic forcing highlighted by several authors (e.g. Pedersen et al., 2010;Spotila and Berger, 2010),, the importance of the glacial erosion appears to be crucial at mid latitude, but more complex at both high and low latitude. Moreover, the relief at mid latitude appears to be higher, hence suggesting a positive correlation between relief and topographic control of glacier on the landscape Champagnac, J.-D., Molnar, P., Sue, C., and Herman, F.: Tectonics, Climate, and Mountain Topography, Journal of Geophysical Research B: Solid Earth, 117, doi:10.1029/2011JB008348, 2012. Egholm, D. L., Nielsen, S. B., Pedersen, V. K., and Lesemann, J. E.: Glacial effects limiting mountain height, Nature, 460, 884-888, 2009. Herman, F., Beaud, F., Champagnac, J.-D., Lemieux, J.-M., and Sternai, P.: Glacial hydrology and erosion patterns: A mechanism for carving glacial valleys, Earth and Planetary Science Letters, 310, 498-508, 2011. Pedersen, V. K., Egholm, D. L., and Nielsen, S. B.: Alpine glacial

  5. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2008-12-01

    . Translated and annotated by Felicia Brichoux (Nicole Revel Joos van Vugt, José Eijt, Marjet Derks (eds; Tempo doeloe, tempo sekarang; Het proces van Indonesianisering in Nederlandse orden en congregaties (Karel Steenbrink Nancy Eberhardt; Imagining the course of life; Self-transformation in a Shan Buddhist community (Nicholas Tapp J.C. Smelik, C.M. Hogenstijn, W.J.M. Janssen; A.J. Duymaer van Twist; Gouverneur-Generaal van Nederlands-Indi? (1851-1856 (Gerard Termorshuizen David Steinberg; Turmoil in Burma; Contested legitimacies in Myanmar (Sean Turnell Carl A. Trocki; Singapore; Wealth, power and the culture of control (Bryan S. Turner Matthew Isaac Cohen; The Komedie Stamboel; Popular theatre in colonial Indonesia, 1891-1903 (Holger Warnk Jörgen Hellman; Ritual fasting on West Java (Robert Wessing Waruno Mahdi; Malay words and Malay things; Lexical souvenirs from an exotic archipelago in German publications before 1700 (Edwin Wieringa RECENT PUBLICATIONS Russell Jones, C.D. Grijns, J.W. de Vries, M. Siegers (eds; Loan-words in Indonesian and Malay VERHANDELINGEN 249 Peter Carey: The power of prophecy. Prince Dipanagara and the end of an old order in Java, 1785-1855

  6. Nuclear power worldwide: Status and outlook

    International Nuclear Information System (INIS)

    2008-01-01

    Full text: Nuclear power, in step with growing global demand for energy, will continue expanding into the next two decades, says the 2008 edition of Energy, Electricity and Nuclear Power Estimates for the Period to 2030, just published by the International Atomic Energy Agency (IAEA). The IAEA report about the prospects for nuclear power, produced every year since 1981, provides high and low projections - very general growth trends whose validity must constantly be subjected to critical review, the report states. The low projection assumes that all nuclear capacity currently under construction or in the development pipeline gets constructed and current policies, such as phaseouts, remain unchanged. In such a scenario there would be growth in nuclear electricity production capacity to 473 gigawatt electrical (GW[e]) from the current 372 GW[e]. (A gigawatt is one billion watts). The IAEA's high projection, based on government and corporate announcements about longer-term plans for nuclear investments, as well as potential new national policies, such as responses to new international environmental agreements to combat climate change, estimates nuclear power electricity capacity would grow to 748 GW[e] by 2030. Rising costs of natural gas and coal, coupled with energy supply security and environmental constraints are among factors contributing to nuclear's growth, said Hans-Holger Rogner, Head of the IAEA's Nuclear Energy Planning and Economic Studies Section. ''The IAEA's higher projection is in step with an anticipated level of 3.2 per cent annual growth in global power generation,'' he said. ''In the low projection, overall global electricity annual growth is 1.9 per cent and nuclear power's share is projected to drop to about 12.5 per cent by 2030.'' From 2007 to 2008 the report says, total global electricity generation rose 4.8% while nuclear power's share dropped to 14% from a nearly steady rate of 16 - 17 per cent between 1986 and 2005. Mr. Rogner said that new

  7. Inside the greenhouse debate. Energy issues set to rise on global warming agenda

    International Nuclear Information System (INIS)

    Anon.

    2000-01-01

    At The Hague in November 2000, pivotal talks on climate change policies and actions - notably ways to cut emissions of greenhouse gases - were suspended after two weeks of intensive debate. Countries now are looking to resume negotiations by June 2001, possibly in Bonn, Germany. Five countries interested in nuclear power under the Clean Development Mechanism (CDM) for reducing greenhouse gas emissions presented national case studies at COP-6. The presentations were made at a ''sidebar'' event introduced by Mr. Hans-Holger Rogner, who heads the IAEA's Planning and Economic Studies Section, Department of Nuclear Energy. Case studies were presented by Mr. R.B. Grover, India; Mr. Chaeyung Lim, Republic of Korea; Mr. Liu Deshun, China; Mr. Le Doan Phac, Viet Nam; and Mr. Muhammad Latif, Pakistan. India's presentation outlined plans to expand electricity production through 2012, including an increase in nuclear capacity. Mr. Grover said that some nuclear power projects are dependent upon receiving financial assistance under the CDM; the dependence is linked to the plant's location relative to India's major coal mines. The Republic of Korea presentation addressed the cost of carbon reduction, noting that reductions using nuclear power would cost about one-tenth of the cost using gas-fired plants in the country. Nuclear power also would contribute to the country's energy security. China's presentation reviewed the country's plans to boost nuclear power capacity over the next 20 years in the face of rising electricity demand, with new plants targeted for coastal regions that are more economically developed. Achieving nuclear expansion plans would result in the annual avoidance of about 63 million tonnes carbon through reduced carbon-dioxide emissions. Nearly 75% of the country's electricity production is now coal-fired, which places a heavy toll on both the environment and transportation requirements. Financial support is needed to more fully develop the nuclear option

  8. I. T. - R. O. C. K. S. Comet Nuclei Sample Return Mission

    Science.gov (United States)

    Dalcher, N.

    2009-04-01

    samples will be performed by touch and go manoeuvres and a penetrator device [10]. Solar arrays are used as energy source and additional cooling is required to keep the samples at low temperatures (Lisse C., Schultz P., Meech K. J., Delamere W. A. Icarus 187,4-15 (2007). [4] Simon S.B., Joswiak D.J., Ishii H.A., Bradley J.P., Chi M., Grossman L., Aléon J., Brownlee D.E., Fallon S., Hutcheon I.D., Matrajt G., Mckeegan K.D.: Refractory Inclusion Returned by Stardust from Comet P81/Wild 2. Meteoritics and Planetary Science (2007). [5] George D. Cody, Harald Ade, Conel M. O'D. Alexander, Tohru Araki, Anna Butterworth, Holger Fleckenstein, George Flynn, Mary K. Gilles, Chris Jacobsen, A.L. D. Kilcoyne, Keiko Messenger, Scott A. Sandford, Tolek Tyliszczak, Andrew J.Westphal4, Susan Wirick, and Hikaru Yabuta. Quantitative Organic and Light Element analysis of Comet 81P/Wild 2 particles using C-, N-, and O- µ-XANES, Meteoretics and Planetary Science: In Press. [6] Stern, S. et al. Alice: The Rosetta Ultraviolet Imaging Spectrograph. Space Science Reviews 128, 507-527 (2007). [7] Balsiger, H. et al. Rosina-Rosetta Orbiter Spectrometer for Ion and Neutral Analysis. Space Science Reviews 128, 745-801 (2007). [8] Colangeli, L. et al. The Grain Impact Analyser and Dust Accumulator (GIADA) Experiment for the Rosetta Mission: Design, Performances and First Results. Space Science Reviews 128, 803-821 (2007). [9] Yoshimitsu, T., Kubota, T., Nakatani, I., Adachi, T. & Saito, H. Micro-hopping robot for asteroid exploration. Acta Astronautica 52, 441-446 (2003). [10] Lorenz, R. et al. Demonstration of comet sample collection by penetrator. ESA SP-542, 387-393 (2003). [11] Küppers et al. Triple F—a comet nucleus sample return mission. Experimental Astronomy, Online First (2008).

  9. Short- and long-term subjective medical treatment outcome of trauma surgery patients: the importance of physician empathy

    Directory of Open Access Journals (Sweden)

    Steinhausen S

    2014-09-01

    Full Text Available Simone Steinhausen,1 Oliver Ommen,2 Sunya-Lee Antoine,1 Thorsten Koehler,3 Holger Pfaff,4 Edmund Neugebauer11Institute for Research in Operative Medicine (IFOM, Witten/Herdecke University, Campus Cologne-Merheim, Germany; 2Federal Centre for Health Education (BZgA, Cologne, Germany; 3Institute for Applied Social Sciences (infas, Bonn, Germany; 4Institute for Medical Sociology, Health Services Research and Rehabilitation Science (IMVR, Faculty of Human Science and Faculty of Medicine, University of Cologne, Germany Purpose: To investigate accident casualties’ long-term subjective evaluation of treatment outcome 6 weeks and 12 months after discharge and its relation to the experienced surgeon’s empathy during hospital treatment after trauma in consideration of patient-, injury-, and health-related factors. The long-term results are compared to the 6-week follow-up outcomes.Patients and methods: Two hundred and seventeen surgery patients were surveyed at 6 weeks, and 206 patients at 12 months after discharge from the trauma surgical general ward. The subjective evaluation of medical treatment outcome was measured 6 weeks and 12 months after discharge with the respective scale from the Cologne Patient Questionnaire. Physician Empathy was assessed with the Consultation and Relational Empathy Measure. The correlation between physician empathy and control variables with the subjective evaluation of medical treatment outcome 12 months after discharge was identified by means of logistic regression analysis under control of sociodemographic and injury-related factors.Results: One hundred and thirty-six patients were included within the logistic regression analysis at the 12-month follow-up. Compared to the 6-week follow-up, the level of subjective evaluation of medical treatment outcome was slightly lower and the association with physician empathy was weaker. Compared to patients who rated the empathy of their surgeon lower than 31 points, patients

  10. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2005-01-01

    Universiteit Leiden. Leiden: Opleiding Talen en Culturen van Zuidoost-Azië en Oceanië, Universiteit Leiden, 2002, xviii + 328 pp. [Semaian 22.], Willem van der Molen (eds -Dick van der Meij, Renato Rosaldo, Cultural citizenship in island Southeast Asia; Nation and belonging in the hinterlands. Berkeley CA: University of California Press, 2003, x + 228 pp. -Lisa Migo, Sjoerd R. Jaarsma, Handle with care; Ownership and control of ethnographic materials. Pittsburgh: University of Pittsburgh Press, 2002, x + 264 pp. [ASAO monograph series 20.] -Jonathan H. Ping, Priyambudi Sulistiyanto, Thailand, Indonesia and Burma in comparative perspective. Aldershot: Ashgate, 2002, xiv + 308 pp. [The international political economy of new regionalisms series.] -Anthony L. Smith, Amitav Acharya, Constructing a security community in Southeast Asia; ASEAN and the problem of regional order. London: Routledge, 2001, xx + 234 pp. -Achmad Sunjayadi, Elsbeth Locher-Scholten ,Hof en handel; Aziatische vorsten en de VOC 1620-1720. Leiden: KITLV Uitgeverij, 2004, x + 350 pp. [Verhandelingen 223.], Peter Rietbergen (eds -Gerard Termorshuizen, Marieke Bloembergen, De koloniale vertoning; Nederland en Indië op de wereldtentoonstellingen (1880-1931. Amsterdam: Wereld-bibliotheek, 2002, 463 pp.''Koloniale inspiratie; Frankrijk, Nederland, Indië en de wereldtentoonstellingen 1883-1931. Leiden: KITLV Uitgeverij, 2004, 256 pp. -Jojanneke van der Toorn, Philip Taylor, Goddess on the rise; Pilgrimage and popular religion in Vietnam. Honolulu: University of Hawaii Press, 2004, x + 332 pp. -Holger Warnk, Azyumardi Azra, The origins of Islamic reformism in Southeast Asia; Networks of Malay-Indonesian and Middle Eastern 'ulama' in the seventeenth and eighteenth century. Leiden: KITLV Press, 2004, ix + 253 pp. -Robert Wessing, Gregory Forth, Beneath the volcano; Religion, cosmology and spirit classification among the Nage of eastern Indonesia. Leiden: KITLV Press, 1998, xi + 369 pp. [Verhandelingen 117.] -Edwin

  11. Increased survival rate by local release of diclofenac in a murine model of recurrent oral carcinoma

    Directory of Open Access Journals (Sweden)

    Will OM

    2016-10-01

    Full Text Available Olga Maria Will,1,* Nicolai Purcz,2,* Athena Chalaris,3 Carola Heneweer,4,5 Susann Boretius,1 Larissa Purcz,2 Lila Nikkola,6 Nureddin Ashammakhi,6 Holger Kalthoff,7 Claus-Christian Glüer,1 Jörg Wiltfang,2 Yahya Açil,2 Sanjay Tiwari1 1Section Biomedical Imaging, Clinic for Radiology and Neuroradiology, MOIN CC, 2Department of Oral and Maxillofacial Surgery, University Hospital Schleswig-Holstein, 3Institute of Biochemistry, Christian-Albrechts-Universität zu Kiel, 4Clinic for Radiology and Neuroradiology, University Hospital Schleswig-Holstein, Kiel, 5Institute for Diagnostic and Interventional Radiology, University Hospital Cologne, Cologne, Germany; 6Department of Biomedical Engineering, Tampere University of Technology, Tampere, Finland; 7Institute for Experimental Cancer Research, University Hospital Schleswig-Holstein, Kiel, Germany *These authors contributed equally to this work Abstract: Despite aggressive treatment with radiation and combination chemotherapy following tumor resection, the 5-year survival rate for patients with head and neck cancer is at best only 50%. In this study, we examined the therapeutic potential of localized release of diclofenac from electrospun nanofibers generated from poly(d,l-lactide-co-glycolide polymer. Diclofenac was chosen since anti-inflammatory agents that inhibit cyclooxygenase have shown great potential in their ability to directly inhibit tumor growth as well as suppress inflammation-mediated tumor growth. A mouse resection model of oral carcinoma was developed by establishing tumor growth in the oral cavity by ultrasound-guided injection of 1 million SCC-9 cells in the floor of the mouth. Following resection, mice were allocated into four groups with the following treatment: 1 no treatment, 2 implanted scaffolds without diclofenac, 3 implanted scaffolds loaded with diclofenac, and 4 diclofenac given orally. Small animal ultrasound and magnetic resonance imaging were utilized for longitudinal

  12. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2008-12-01

    Full Text Available Michele Stephen; Desire, divine and demonic; Balinese mysticism in the paintings of I Ketut Budiana and I Gusti Nyoman Mirdiana (Andrea Acri John Lynch (ed.; Issues in Austronesian historical phonology (Alexander Adelaar Alfred W. McCoy; The politics of heroin; CIA complicity in the global drug trade (Greg Bankoff Anthony Reid; An Indonesian frontier; Acehnese and other histories of Sumatra (Timothy P. Barnard John G. Butcher; The closing of the frontier; A history of the maritime fisheries of Southeast Asia c. 1850-2000 (Peter Boomgaard Francis Loh Kok Wah, Joakim Öjendal (eds; Southeast Asian responses to globalization; Restructuring governance and deepening democracy (Alexander Claver I Wayan Arka; Balinese morpho-syntax: a lexical-functional approach (Adrian Clynes Zaharani Ahmad; The phonology-morphology interface in Malay; An optimality theoretic account (Abigail C. Cohn Michael C. Ewing; Grammar and inference in conversation; Identifying clause structure in spoken Javanese (Aone van Engelenhoven Helen Creese; Women of the kakawin world; Marriage and sexuality in the Indic courts of Java and Bali (Amrit Gomperts Ming Govaars; Dutch colonial education; The Chinese experience in Indonesia, 1900-1942 (Kees Groeneboer Ernst van Veen, Leonard Blussé (eds; Rivalry and conflict; European traders and Asian trading networks in the 16th and 17th centuries (Hans Hägerdal Holger Jebens; Pathways to heaven; Contesting mainline and fundamentalist Christianity in Papua New Guinea (Menno Hekker Ota Atsushi; Changes of regime and social dynamics in West Java; Society, state and the outer world of Banten, 1750-1830 (Mason C. Hoadley Richard McMillan; The British occupation of Indonesia 1945-1946; Britain, the Netherlands and the Indonesian Revolution (Russell Jones H.Th. Bussemaker; Bersiap! Opstand in het paradijs; De Bersiapperiode op Java en Sumatra 1945-1946 (Russell Jones Michael Heppell; Limbang anak

  13. Book reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2009-10-01

    Full Text Available Des Alwi, Friends and exiles; A memoir of the nutmeg isles and the Indonesian nationalist movement. (Chris F. van Fraassen James A. Anderson, The rebel den of Nùng Trí Cao; Loyalty and identity along the Sino-Vietnamese frontier. (Emmanuel Poisson Reggie Baay, De njai; Het concubinaat in Nederlands-Indië. (Maya Sutedja-Liem John Barker (ed., The anthropology of morality in Melanesia and beyond. (Jaap Timmer Kees Buijs, Powers of blessing from the wilderness and from heaven; Structure and transformations in the religion of the Toraja in the Mamasa area of South Sulawesi. (Robert Wessing Jamie S. Davidson, From rebellion to riots; Collective violence on Indonesian Borneo. (Victor T. King Kees van Dijk, The Netherlands Indies and the Great War, 1914-1918. (Jaap Anten Linda España-Maram, Creating masculinity in Los Angeles’ Little Manila; Working-class Filipinos and popular culture, 1920s-1950s. (John D. Blanco Renate Carstens, Durch Asien im Horizont des Goethekreises; Neue Facetten im Wirken Goethes. (Edwin Wieringa James T. Collins, Bahasa Sanskerta dan Bahasa Melayu. (Arlo Griffiths Victoria M. Clara van Groenendael, Jaranan; The horse dance and trance in East Java. (Dick van der Meij Paul M. Handley, The king never smiles; A biography of Thailand’s Bhumibol Adulyadej. (Jeroen Rikkerink Holger Jebens, Kago und kastom; Zum Verhältnis von kultureller Fremd- und Selbstwahrnehmung in West New Britain (Papua-Neuguinea. (Menno Hekker Lee Hock Guan and Leo Suryadinata (eds, Language, nation and development in Southeast Asia. (Renata M. Lesner-Szwarc Ross H. McLeod and Andrew MacIntyre (eds, Indonesia; Democracy and the promise of good governance. AND Patrick Ziegenhain, The Indonesian parliament and democratization. (Henk Schulte Nordholt Laurent Sagart, Roger M. Blench, and Alicia Sanchez-Mazas (eds, The peopling of East Asia; Putting together archaeology, linguistics and genetics. (Alexander

  14. How stable are quantitative sensory testing measurements over time? Report on 10-week reliability and agreement of results in healthy volunteers

    Directory of Open Access Journals (Sweden)

    Nothnagel H

    2017-08-01

    Full Text Available Helen Nothnagel,1,2,* Christian Puta,1,3,* Thomas Lehmann,4 Philipp Baumbach,5 Martha B Menard,6,7 Brunhild Gabriel,1 Holger H W Gabriel,1 Thomas Weiss,8 Frauke Musial2 1Department of Sports Medicine and Health Promotion, Friedrich Schiller University, Jena, Germany; 2Department of Community Medicine, National Research Center in Complementary and Alternative Medicine, UiT, The Arctic University of Norway, Tromsø, Norway; 3Center for Interdisciplinary Prevention of Diseases Related to Professional Activities, 4Department of Medical Statistics, Computer Sciences and Documentation, Friedrich Schiller University, 5Department of Anesthesiology and Intensive Care Medicine, University Hospital Jena, Germany; 6Crocker Institute, Kiawah Island, SC, 7School of Integrative Medicine and Health Sciences, Saybrook University, Oakland, CA, USA; 8Department of Biological and Clinical Psychology, Friedrich Schiller University, Jena, Germany *These authors contributed equally to this work Background: Quantitative sensory testing (QST is a diagnostic tool for the assessment of the somatosensory system. To establish QST as an outcome measure for clinical trials, the question of how similar the measurements are over time is crucial. Therefore, long-term reliability and limits of agreement of the standardized QST protocol of the German Research Network on Neuropathic Pain were tested. Methods: QST on the lower back and hand dorsum (dominant hand were assessed twice in 22 healthy volunteers (10 males and 12 females; mean age: 46.6±13.0 years, with sessions separated by 10.0±2.9 weeks. All measurements were performed by one investigator. To investigate long-term reliability and agreement of QST, differences between the two measurements, correlation coefficients, intraclass correlation coefficients (ICCs, Bland–Altman plots (limits of agreement, and standard error of measurement were used. Results: Most parameters of the QST were reliable over 10 weeks in

  15. Anticonvulsant effects of isomeric nonimidazole histamine H3 receptor antagonists

    Directory of Open Access Journals (Sweden)

    Sadek B

    2016-11-01

    Full Text Available Bassem Sadek,1 Ali Saad,1 Johannes Stephan Schwed,2,3 Lilia Weizel,2 Miriam Walter,2 Holger Stark2,3 1Department of Pharmacology and Therapeutics, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates; 2Biocenter, Institute of Pharmaceutical Chemistry, Goethe University, Frankfurt, Germany; 3Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany Abstract: Phenytoin (PHT, valproic acid, and modern antiepileptic drugs (AEDs, eg, remacemide, loreclezole, and safinamide, are only effective within a maximum of 70%–80% of epileptic patients, and in many cases the clinical use of AEDs is restricted by their side effects. Therefore, a continuous need remains to discover innovative chemical entities for the development of active and safer AEDs. Ligands targeting central histamine H3 receptors (H3Rs for epilepsy might be a promising therapeutic approach. To determine the potential of H3Rs ligands as new AEDs, we recently reported that no anticonvulsant effects were observed for the (S-2-(4-(3-(piperidin-1-ylpropoxybenzylaminopropanamide (1. In continuation of our research, we asked whether anticonvulsant differences in activities will be observed for its R-enantiomer, namely, (R-2-(4-(3-(piperidin-1-ylpropoxybenzylaminopropaneamide (2 and analogs thereof, in maximum electroshock (MES-, pentylenetetrazole (PTZ-, and strychnine (STR-induced convulsion models in rats having PHT and valproic acid (VPA as reference AEDs. Unlike the S-enantiomer (1, the results show that animals pretreated intraperitoneally (ip with the R-enantiomer 2 (10 mg/kg were moderately protected in MES and STR induced models, whereas proconvulsant effect was observed for the same ligand in PTZ-induced convulsion models. However, animals pretreated with intraperitoneal doses of 5, 10, or 15 mg/kg of structurally bulkier (R-enantiomer (3

  16. PREFACE: 6th International Conference on Aperiodic Crystals (APERIODIC'09)

    Science.gov (United States)

    Grimm, Uwe; McGrath, Rónán; Degtyareva, Olga; Sharma, Hem Raj

    2010-04-01

    on quasicrystals (Eiji Abe), complex metal alloys (Alessandra Beni) and incommensurately modulated structures (Gervais Chapuis). While these were mainly aimed at younger researchers in the field, the lectures were very well attended and appreciated by the participants. The main programme ran from Monday morning until Friday lunchtime. It comprised 13 invited and 40 contributed plenary talks, and more than 40 posters, which were presented at two afternoon/evening poster sessions. The topics covered in the programme range from mathematical foundations, mathematical models, new materials, sample preparation, structure determination, physical properties and surface properties to industrial applications. Every presenter was invited to submit an article for this proceedings volume, and the 36 peer-reviewed papers in this volume present a cross-section of the range of presentations at the conference. They have been arranged into four categories, (i) quasicrystals, (ii) modulated structures, (iii) mathematical and theoretical aspects of aperiodic order, and (iv) approximants and complex phases. Prizes for best student presentations were awarded to Heinrich Orsini-Rosenberg (ETH Zurich) for his poster Tailor-made sevenfold approximants: ab-initio investigations on formation and stability and to Holger Euchner (Universität Stuttgart) for his contributed talk on Lattice dynamics in complex metallic alloys - vibrational properties of Zn11Mg2. In addition to a cash prize, Heinrich Orsini-Rosenberg received an icosahedral teapot, which was manufactured and donated by David Warrington, and Holger Euchner received a book prize. The meeting started with a welcome reception in the University's recently refurbished Victoria Gallery and Museum. A public lecture Simple sets of shapes that tile the plane but cannot ever repeat by Professor Sir Roger Penrose FRS attracted a wide audience and gave a fascinating insight into the discovery of the Penrose tiling, which is still the paradigm

  17. Selective crystallization of cations with crown ethers

    International Nuclear Information System (INIS)

    Heffels, Dennis Egidius

    2014-01-01

    structures can be assigned to general structure types already found by Pedersen, among them two silver compounds with the rather rare 2:3 type structure.

  18. Experimental Investigation of the Role of Ions in Aerosol Nucleation

    Science.gov (United States)

    Pedersen, J. P.; Enghoff, M. B.; Bondo, T.; Johnson, M. S.; Paling, S.; Svensmark, H.

    2008-12-01

    , I., Lenschow, D., Bandy, A.R., Thornton, D., Moore, K., Mauldin, L., Tanner, D., Litchy, M., Carroll, M.A. Collins, J. & Albercook, G. (1998), Science 282, 89--92 Svensmark, H, Pedersen, J.O.P, Marsh, N.D., Enghoff, M.B. & Uggerhøj, U.I. (2007), Proc. R. Soc. A 463, 385--396.

  19. Dynamics and life histories of northern ungulates in changing environments

    Science.gov (United States)

    Hendrichsen, D. K.

    2011-12-01

    , 23: 437-443 Coulson T, Catchpole EA, Albon SD, Morgan BJT, Pemberton JM, Clutton-Brock TH, Crawley MJ and Grenfell BT. 2001. Age, sex, density, winter weather, and population crashes in Soay sheep. Science, 292: 1528-1531 Post, E and Stenseth NC. 1999. Climatic variability, plant phenology, and northern ungulates. Ecology, 80: 1322-1339 Post E, Pedersen C, Wilmers CC and Forchhammer MC. 2008. Warming, plant phenology and the spatial dimension of trophic mismatch for large herbivores. Proc. Roy Soc. B., 275: 2005-2013 Tyler NJC, Forchhammer MC and Øritsland NA. 2008. Nonlinear effects of climate and density in the dynamics of a fluctuating population of reindeer. Ecology, 89: 1675-1686

  20. Changes in coronary heart disease risk profiles of HIV patients in Zimbabwe over 9 months: a follow-up study

    Directory of Open Access Journals (Sweden)

    Zhou DT

    2016-10-01

    Full Text Available Danai Tavonga Zhou,1,2 Olav Oektedalen,3 Sandra Shawarira-Bote,4 Babill Stray-Pedersen5 1Department of Medical Laboratory Sciences, College of Health Sciences, University of Zimbabwe, Avondale, Harare, Zimbabwe; 2Institute of Clinical Medicine, University of Oslo, 3Department of Infectious Diseases, Oslo University Hospital, Oslo, Norway; 4Newlands Clinic, Harare, Zimbabwe; 5Institute of Clinical Medicine, University in Oslo and Womens Clinic, Oslo University Hospital, Oslo, Norway Abstract: Dyslipidemia, hypertension, inflammation, and coronary heart disease (CHD are adverse events in human immunodeficiency virus (HIV-infected patients even if they are receiving antiretroviral therapy (ART. Yet, data on CHD risk induced by HIV or ART in sub-Saharan Africa are limited. The aim of this longitudinal study was to describe changes in CHD risk profiles measured by lipids, inflammatory markers, and Framingham scores among HIV-positive patients previously reported from Harare, Zimbabwe. Patients were grouped into ART-experienced patients (n=147 and ART-naïve patients (n=23 and followed up for 9 months. Generalized least squares random-effects modeling was applied to explain changes in total cholesterol (TC, high-density lipoprotein (HDL, low-density lipoprotein, TC/HDL ratio, myeloperoxidase, highly sensitive C-reactive protein, and Framingham scores over the 9-month period. Independent variables included age, sex, monthly earning, body mass index, systolic blood pressure (SBP, diastolic blood pressure, duration of HIV diagnosis, duration of ART, viral load, and CD4 count. In ART-experienced patients, there was a substantial decrease in TC over time, ART-negative patients showed a significant increase in TC and HDL over time, and the increase in TC was associated with high viral load and low duration of HIV diagnosis, while increase in HDL was associated with young age, low body mass index, and low SBP. Framingham risk scores increased with time in

  1. Mesoscale ionospheric electrodynamics of omega bands determined from ground-based electromagnetic and satellite optical observations

    Directory of Open Access Journals (Sweden)

    O. Amm

    2005-02-01

    Full Text Available We present ground-based electromagnetic data from the MIRACLE and BEAR networks and satellite optical observations from the UVI and PIXIE instruments on the Polar satellite of an omega band event over Northern Scandinavia on 26 June 1998, which occured close to the morning side edge of a substorm auroral bulge. Our analysis of the data concentrates on one omega band period from 03:18-03:27 UT, for which we use the method of characteristics combined with an analysis of the UVI and PIXIE data to derive a time series of instantaneous, solely data-based distributions of the mesoscale ionospheric electrodynamic parameters with a 1-min time resolution. In addition, the AMIE method is used to derive global Hall conductance patterns. Our results show that zonally alternating regions of enhanced ionospheric conductances ("tongues" up to ~60S and low conductance regions are associated with the omega bands. The tongues have a poleward extension of ~400km from their base and a zonal extension of ~380km. While they are moving coherently eastward with a velocity of ~770ms-1, the structures are not strictly stationary. The current system of the omega band can be described as a superposition of two parts: one consists of anticlockwise rotating Hall currents around the tongues, along with Pedersen currents, with a negative divergence in their centers. The sign of this system is reversing in the low conductance areas. It causes the characteristic ground magnetic signature. The second part consists of zonally aligned current wedges of westward flowing Hall currents and is mostly magnetically invisible below the ionosphere. This system dominates the field-aligned current (FAC pattern and causes alternating upward and downward FAC at the flanks of the tongues with maximum upward FAC of ~25µA m-2. The total FAC of ~2MA are comparable to the ones diverted inside a westward traveling surge. Throughout the event, the overwhelming part of the FAC are associated with

  2. Mesoscale ionospheric electrodynamics of omega bands determined from ground-based electromagnetic and satellite optical observations

    Directory of Open Access Journals (Sweden)

    O. Amm

    2005-02-01

    Full Text Available We present ground-based electromagnetic data from the MIRACLE and BEAR networks and satellite optical observations from the UVI and PIXIE instruments on the Polar satellite of an omega band event over Northern Scandinavia on 26 June 1998, which occured close to the morning side edge of a substorm auroral bulge. Our analysis of the data concentrates on one omega band period from 03:18-03:27 UT, for which we use the method of characteristics combined with an analysis of the UVI and PIXIE data to derive a time series of instantaneous, solely data-based distributions of the mesoscale ionospheric electrodynamic parameters with a 1-min time resolution. In addition, the AMIE method is used to derive global Hall conductance patterns. Our results show that zonally alternating regions of enhanced ionospheric conductances ("tongues" up to ~60S and low conductance regions are associated with the omega bands. The tongues have a poleward extension of ~400km from their base and a zonal extension of ~380km. While they are moving coherently eastward with a velocity of ~770ms-1, the structures are not strictly stationary. The current system of the omega band can be described as a superposition of two parts: one consists of anticlockwise rotating Hall currents around the tongues, along with Pedersen currents, with a negative divergence in their centers. The sign of this system is reversing in the low conductance areas. It causes the characteristic ground magnetic signature. The second part consists of zonally aligned current wedges of westward flowing Hall currents and is mostly magnetically invisible below the ionosphere. This system dominates the field-aligned current (FAC pattern and causes alternating upward and downward FAC at the flanks of the tongues with maximum upward FAC of ~25µA m-2. The total FAC of ~2MA are comparable to the ones diverted inside a westward traveling surge. Throughout the event, the overwhelming part of the FAC

  3. Cost-effectiveness of SQ® HDM SLIT-tablet in addition to pharmacotherapy for the treatment of house dust mite allergic rhinitis in Germany

    Directory of Open Access Journals (Sweden)

    Green W

    2017-02-01

    Full Text Available William Green,1 Jörg Kleine-Tebbe,2 Ludger Klimek,3 Julie Hahn-Pedersen,4 Jakob Nørgaard Andreasen,4 Matthew Taylor1 1York Health Economics Consortium, University of York, York, UK; 2Allergy and Asthma Center, Westend, Berlin, 3Center for Rhinology and Allergology, Wiesbaden, Germany; 4ALK-Abelló, Hørsholm, Denmark Background: Allergic rhinitis is a global health problem that burdens society due to associated health care costs and its impact on health. Standardized quality (SQ® house dust mite (HDM sublingual immunotherapy (SLIT-tablet is a sublingually administered allergy immunotherapy tablet for patients with persistent moderate to severe HDM allergic rhinitis despite use of allergy pharmacotherapy.Objective: To assess the cost-effectiveness of SQ HDM SLIT-tablet in Germany for patients suffering from HDM allergic rhinitis.Methods: A pharmacoeconomic analysis, based on data collected in a double-blinded, phase III randomized placebo-controlled trial (n=992, was undertaken to compare SQ HDM SLIT-tablet in addition to allergy pharmacotherapy to placebo plus allergy pharmacotherapy. Quality-adjusted life year (QALY scores and health care resource use data recorded in the trial were applied to each treatment group and extrapolated over a nine-year time horizon. A series of scenarios were used to investigate the impact of changes on long-term patient health for both treatment groups, which was measured by annual changes in QALY scores. Deterministic and probabilistic sensitivity analyses were also performed. Results: In the base case analysis, compared with allergy pharmacotherapy, SQ HDM SLIT-tablet led to a QALY gain of 0.31 at an incremental cost of €2,276 over the nine-year time horizon, equating to an incremental cost-effectiveness ratio of €7,519. The treatment was cost-effective for all scenarios analyzed; however, results were sensitive to changes in individual parameter values during the deterministic sensitivity analysis

  4. Positive predictive value and completeness of prenatally assigned International Classification of Disease-10 kidney anomaly diagnoses in the Danish National Patient Registry

    Directory of Open Access Journals (Sweden)

    Rasmussen M

    2016-01-01

    Full Text Available Maria Rasmussen,1 Morten Smærup Olsen,2 Lone Sunde,1,3 Lars Pedersen,2 Olav Bjørn Petersen4 1Department of Clinical Genetics, Aarhus University Hospital, Skejby, 2Department of Clinical Epidemiology, Aarhus University Hospital, Skejby, 3Department of Biomedicine, Aarhus University, Aarhus, 4Department of Gynecology and Obstetrics, Aarhus University Hospital, Skejby, Denmark Objective: Restricting studies of severe congenital malformations to live-born children may introduce substantial bias. In this study, we estimated the attendance to the second-trimester fetal malformation screening program. We also estimated the positive predictive value (PPV of prenatally assigned International Classification of Disease-10 diagnoses recorded in the Danish National Patient Registry (DNPR and the completeness of case registration. We used kidney anomalies as an example. Methods: We identified the proportion of all Danish live-born children from January 1, 2007 to December 31, 2012, who were scanned during the second trimester using the DNPR and the Civil Registration System. Details of all fetuses with specific kidney anomaly diagnoses according to the DNPR were retrieved. The PPV was estimated using the nationwide Astraia database of pregnancy medical charts or traditional medical charts, as gold standard. The completeness was assessed using the total number of cases estimated by the capture–recapture method. Results: Of 372,263 live born infants, 97.3% were scanned during the second trimester. We identified 172 fetuses in the DNPR. Of these, 149 had kidney anomalies according to Astraia or medical chart review, corresponding to a PPV of 87% (95% CI: 81%–91%. The estimated completeness was 43% (95% CI: 38%–49% for the DNPR and 75% (95% CI: 70%–79% for Astraia. Conclusion: Almost all live-born children were scanned during the second trimester in Denmark. However, low completeness may hamper the use of the DNPR for studies of prenatally detected

  5. Supporting middle school students' construction of evidence-based arguments: Impact of and student interactions with computer-based argumentation scaffolds

    Science.gov (United States)

    Belland, Brian Robert

    Middle school students have difficulty creating evidence-based arguments (EBAs) during problem-based learning (PBL) units due to challenges (a) adequately representing the unit's central problem (Ge & Land, 2004; Liu & Bera, 2005), (b) determining and obtaining the most relevant evidence (Pedersen & Liu, 2002-2003), and (c) synthesizing gathered information to construct a sound argument (Cho & Jonassen, 2002). I designed and developed the Connection Log to support middle school students in this process. This study addressed (1) the Connection Log's impact on (a) argument evaluation ability, and (b) group argument quality and (2) how and why middle school science students used the Connection Log. Four sections of a 7th-grade science class participated. Student groups selected a stakeholder position related to the Human Genome Project (HGP) and needed to decide on and promote a plan to use $3 million to further their position as pertains to the HGP. I randomly assigned one higher-achieving and one lower-achieving class to Connection Log or no Connection Log conditions. Students completed an argument evaluation test, and impact on argument evaluation ability was determined using nested ANOVA. Two graduate students, blind to treatment conditions, rated group arguments, and impact on group argument quality was determined using nested MANOVA. To determine how and why students used the Connection Log, I videotaped and interviewed one small group from each class in the experimental condition. I coded transcripts and generated themes, triangulating the two data sources with informal observations during all class sessions and what students wrote in the Connection Log. I detected no significant differences on claim, evidence, or connection of claim to evidence ratings of debate performances. However, students used the Connection Log to counter different difficulties, and I found a significant main effect of the Connection Log on argument evaluation ability, as well as a

  6. Risk of pneumonia and urinary tract infection within the first week after total hip arthroplasty and the impact on survival

    Directory of Open Access Journals (Sweden)

    Glassou EN

    2017-01-01

    Full Text Available Eva N Glassou,1,2 Torben B Hansen,1,3 Alma B Pedersen2 1University Clinic of Hand, Hip and Knee Surgery, Department of Orthopedic Surgery, Regional Hospital West Jutland, Aarhus University, 2Department of Clinical Epidemiology, Aarhus University Hospital, 3The Lundbeck Foundation Centre for Fast-track Hip and Knee Replacement, Aarhus University, Aarhus, Denmark Background: Pneumonia and urinary tract infections (UTIs increase morbidity and mortality. There is little epidemiological evidence from large population-based studies on risk factors for these infections and subsequent mortality in total hip arthroplasty (THA patients.Aim: To examine the risk factors of postoperative pneumonia and UTI after THA and their impact on survival.Patients and methods: We used the Danish Hip Arthroplasty Register to identify THAs due to osteoarthritis registered from 2000 to 2013. We collected data about comorbidities, mortality and infections in relation to primary hospitalization and potential predictive variables from administrative databases. Regression models were used to estimate associations between potential risk factors and infection, and subsequently, between infection and mortality.Results: In total 84,812 THAs were included. The cumulative incidence of pneumonia and UTI within 7 days of the primary procedure were 0.21 (95% confidence interval [CI]: 0.18–0.25 and 0.29 (95% CI: 0.26–0.33, respectively. Patient-related risk factors for infection were being 80 years or older, gender and a comorbidity burden at time of surgery. The hazard ratio (HR of dying within 90 days of the primary THA was 10.67 (95% CI: 5.79–19.57 compared to patients without pneumonia. For patients with UTIs, the HR was 1.64 (95% CI: 0.41–6.59 compared to those without a UTI.Conclusion: Pneumonia was associated with an increased short-term risk of dying, despite adjustment for coexisting comorbidity and other potential confounders. Age, gender and comorbidity were the most

  7. Adverse pregnancy outcomes after exposure to methylphenidate or atomoxetine during pregnancy

    Directory of Open Access Journals (Sweden)

    Bro SP

    2015-01-01

    Full Text Available Søren Pauli Bro,1 Maiken Ina Siegismund Kjaersgaard,2 Erik Thorlund Parner,2 Merete Juul Sørensen,3 Jørn Olsen,4 Bodil Hammer Bech,4 Lars Henning Pedersen,4,5 Jakob Christensen,6,7 Mogens Vestergaard11Research Unit and Section for General Practice, Department of Public Health, 2Section for Biostatistics, Department of Public Health, Aarhus University, 3Regional Center for Child and Adolescent Psychiatry, Aarhus University Hospital, 4Section for Epidemiology, Department of Public Health, 5Department of Clinical Medicine – Obstetrics and Gynecology, Aarhus University, 6Department of Clinical Pharmacology, 7Department of Neurology, Aarhus University Hospital, Aarhus, DenmarkObjective: To determine if prenatal exposure to methylphenidate (MPH or atomoxetine (ATX increases the risk of adverse pregnancy outcomes in women with attention deficit/hyperactivity disorder (ADHD.Materials and methods: This was a population-based cohort study of all pregnancies in Denmark from 1997 to 2008. Information on use of ADHD medication, ADHD diagnosis, and pregnancy outcomes was obtained from nationwide registers.Results: We identified 989,932 pregnancies, in which 186 (0.02% women used MPH/ATX and 275 (0.03% women had been diagnosed with ADHD but who did not take MPH/ATX. Our reference pregnancies had no exposure to MPH/ATX and no ADHD diagnosis. Exposure to MPH/ATX was associated with an increased risk of spontaneous abortion (SA; ie, death of an embryo or fetus in the first 22 weeks of gestation (adjusted relative risk [aRR] 1.55, 95% confidence interval [CI] 1.03–2.36. The risk of SA was also increased in pregnancies where the mother had ADHD but did not use MPH/ATX (aRR 1.56, 95% CI 1.11–2.20. The aRR of Apgar scores <10 was increased among exposed women (aRR 2.06, 95% CI 1.11–3.82 but not among unexposed women with ADHD (aRR 0.99, 95% CI 0.48–2.05.Conclusion: MPH/ATX was associated with a higher risk of SA, but our study indicated that it may at

  8. Global auroral conductance distribution due to electron and proton precipitation from IMAGE-FUV observations

    Directory of Open Access Journals (Sweden)

    V. Coumans

    2004-04-01

    Full Text Available The Far Ultraviolet (FUV imaging system on board the IMAGE satellite provides a global view of the north auroral region in three spectral channels, including the SI12 camera sensitive to Doppler shifted Lyman-α emission. FUV images are used to produce instantaneous maps of electron mean energy and energy fluxes for precipitated protons and electrons. We describe a method to calculate ionospheric Hall and Pedersen conductivities induced by auroral proton and electron ionization based on a model of interaction of auroral particles with the atmosphere. Different assumptions on the energy spectral distribution for electrons and protons are compared. Global maps of ionospheric conductances due to instantaneous observation of precipitating protons are calculated. The contribution of auroral protons in the total conductance induced by both types of auroral particles is also evaluated and the importance of proton precipitation is evaluated. This method is well adapted to analyze the time evolution of ionospheric conductances due to precipitating particles over the auroral region or in particular sectors. Results are illustrated with conductance maps of the north polar region obtained during four periods with different activity levels. It is found that the proton contribution to conductance is relatively higher during quiet periods than during substorms. The proton contribution is higher in the period before the onset and strongly decreases during the expansion phase of substorms. During a substorm which occurred on 28 April 2001, a region of strong proton precipitation is observed with SI12 around 14:00MLT at ~75° MLAT. Calculation of conductances in this sector shows that neglecting the protons contribution would produce a large error. We discuss possible effects of the proton precipitation on electron precipitation in auroral arcs. The increase in the ionospheric conductivity, induced by a former proton precipitation can reduce the potential drop

  9. Global auroral conductance distribution due to electron and proton precipitation from IMAGE-FUV observations

    Directory of Open Access Journals (Sweden)

    V. Coumans

    2004-04-01

    Full Text Available The Far Ultraviolet (FUV imaging system on board the IMAGE satellite provides a global view of the north auroral region in three spectral channels, including the SI12 camera sensitive to Doppler shifted Lyman-α emission. FUV images are used to produce instantaneous maps of electron mean energy and energy fluxes for precipitated protons and electrons. We describe a method to calculate ionospheric Hall and Pedersen conductivities induced by auroral proton and electron ionization based on a model of interaction of auroral particles with the atmosphere. Different assumptions on the energy spectral distribution for electrons and protons are compared. Global maps of ionospheric conductances due to instantaneous observation of precipitating protons are calculated. The contribution of auroral protons in the total conductance induced by both types of auroral particles is also evaluated and the importance of proton precipitation is evaluated. This method is well adapted to analyze the time evolution of ionospheric conductances due to precipitating particles over the auroral region or in particular sectors. Results are illustrated with conductance maps of the north polar region obtained during four periods with different activity levels. It is found that the proton contribution to conductance is relatively higher during quiet periods than during substorms. The proton contribution is higher in the period before the onset and strongly decreases during the expansion phase of substorms. During a substorm which occurred on 28 April 2001, a region of strong proton precipitation is observed with SI12 around 14:00MLT at ~75° MLAT. Calculation of conductances in this sector shows that neglecting the protons contribution would produce a large error. We discuss possible effects of the proton precipitation on electron precipitation in auroral arcs. The increase in the ionospheric conductivity, induced by a former proton precipitation can reduce the potential drop

  10. Development of a pan-Arctic monitoring plan for polar bears: Background paper

    Science.gov (United States)

    Vongraven, Dag; Peacock, Lily

    2011-01-01

    Polar bears (Ursus maritimus), by their very nature, and the extreme, remote environment in which they live, are inherently difficult to study and monitor. Monitoring polar bear populations is both arduous and costly and, to be effective, must be a long-term commitment. There are few jurisdictional governments and management boards with a mandate for polar bear research and management, and many have limited resources. Although population monitoring of polar bears has been a focus to some degree within most jurisdictions around the Arctic, of the 19 subpopulations recognised by the IUCN/Species Survival Commission Polar Bear Specialist Group (PBSG), adequate scientific trend data exist for only three of the subpopulations, fair trend data for five and poor or no trend data for the remaining 11 subpopulations (PBSG 2010a). There are especially critical knowledge gaps for the subpopulations in East Greenland, in the Russian Kara and Laptev seas, and in the Chukchi Sea, which is shared between Russia and the United States. The range covered by these subpopulations represents a third of the total area (approx. 23 million km2) of polar bears’ current range, and more than half if the Arctic Basin is included. If we use popular terms, we know close to nothing about polar bears in this portion of their range.As summer sea-ice extent, and to a lesser degree, spring-time extent, continues to retreat, outpacing model forecasts (Stroeve et al. 2007, Pedersen et al. 2009), polar bears face the challenge of adapting to rapidly changing habitats. There is a need to use current and synthesised information across the Arctic, and to develop new methods that will facilitate monitoring to generate new knowledge at a pan-Arctic scale. The circumpolar dimension can be lost when efforts are channelled into regional monitoring. Developing and implementing a plan that harmonises local, regional and global efforts will increase our power to detect and understand important trends for polar

  11. Geochemical And Hydrodynamic Behavior Of The Karstic Aquifer System In The Portion Between Akumal And Boca Paila, In The South Eastern Coast Of The Yucatan Peninsula.

    Science.gov (United States)

    Velazquez Oliman, G.; Leal Bautista, R. M.; Perry, E. C.; Carrol, M.; Wagner, N.; Castillo Oliman, P.

    2008-12-01

    oxygen and hydrogen isotope data are being collected from groundwater and local precipitation for future use in tracing movement of tropical storm recharge through the aquifer system (Pedersen et al, 2005).

  12. Relationships between resting conductances, excitability, and t-system ionic homeostasis in skeletal muscle.

    Science.gov (United States)

    Fraser, James A; Huang, Christopher L-H; Pedersen, Thomas H

    2011-07-01

    Activation of skeletal muscle fibers requires rapid sarcolemmal action potential (AP) conduction to ensure uniform excitation along the fiber length, as well as successful tubular excitation to initiate excitation-contraction coupling. In our companion paper in this issue, Pedersen et al. (2011. J. Gen. Physiol. doi:10.1085/jgp.201010510) quantify, for subthreshold stimuli, the influence upon both surface conduction velocity and tubular (t)-system excitation of the large changes in resting membrane conductance (G(M)) that occur during repetitive AP firing. The present work extends the analysis by developing a multi-compartment modification of the charge-difference model of Fraser and Huang to provide a quantitative description of the conduction velocity of actively propagated APs; the influence of voltage-gated ion channels within the t-system; the influence of t-system APs on ionic homeostasis within the t-system; the influence of t-system ion concentration changes on membrane potentials; and the influence of Phase I and Phase II G(M) changes on these relationships. Passive conduction properties of the novel model agreed with established linear circuit analysis and previous experimental results, while key simulations of AP firing were tested against focused experimental microelectrode measurements of membrane potential. This study thereby first quantified the effects of the t-system luminal resistance and voltage-gated Na(+) channel density on surface AP propagation and the resultant electrical response of the t-system. Second, it demonstrated the influence of G(M) changes during repetitive AP firing upon surface and t-system excitability. Third, it showed that significant K(+) accumulation occurs within the t-system during repetitive AP firing and produces a baseline depolarization of the surface membrane potential. Finally, it indicated that G(M) changes during repetitive AP firing significantly influence both t-system K(+) accumulation and its influence on the

  13. Changes of the groundwater composition in fractured rocks of low permeability as a consequence of deglaciation

    International Nuclear Information System (INIS)

    Delos, A.; Duro, L.; Guimera, J.; Bruno, J.; Puigdomenech, I.

    2005-01-01

    Full text of publication follows: The Swedish concept of a spent fuel repository is based on deep geological disposal in granitic bedrock under geochemically reducing conditions. Groundwaters in areas that have been subjected to advance and retreat of glacial sheets such as the Canadian and Scandic shields, display a signature of deep penetration of oxidant waters such as melt waters, likely to affect the stability of the repository. Some studies have been focused on new experimental methodologies to understand the depletion of oxygen in granitic rocks. They determine how the oxygen reacts with rocks mineral and the water conducting zones [1]. A former study analyses the redox front migration due to the effect of the oxygen intrusion [2]. It concluded that the oxygen in groundwater derived from ice melting would be consumed by the rock minerals, and that the Eh of the system would be oxidising in case of very high groundwater velocities are maintained over long time periods. This work was reviewed by [3] and considered over-conservative and too much simplistic. The objective of this present work is to calculate the impacts of the ice melt on the composition of groundwater likely to reach the repository by means of multicomponent reactive transport simulations. The latest updates of the thermodynamic and kinetic databases will allow more accurate understanding of the processes occurring in the system. The latest hydrogeological, geochemical and mineralogical characterizations performed in the Foersmark region are used in the definition of the more realistic 2D conceptual model. [1] Puigdomenech, I., J.P. Ambrosi, L. Eisenlohr, J.E. Lartigue, S.A. Banwart, K. Bateman, A.E. Milodowski, J. M. West, L. Griffault, E. Gustafsson, K. Hama, H. Yoshida, S. Kotelkinova, K. Pedersen, V. Michaud, L. Trotignon, J. Rivas-Perez and E.L. Tullborg (2001) O 2 depletion in granitic media. The REX project. SKB TR-01-05, 92 pp. [2] Guimera, J., L.Duro, S.Jordana and J.Bruno (1999

  14. Luvica I

    Directory of Open Access Journals (Sweden)

    Bojan Čop

    1956-12-01

    Full Text Available Dans son compte-rendu de Otten, Z. gramm. und lex. Bestimmung des Luv., M. Laroche a éclairé d'une manière incontestable le sens de ce mot: BiOr. XI, 1954, p. 124, il montre que ulantiš sert d'opposé à huiiduuališ de la ligne précédente; pour celui-ci, Otten, op. cit., p. 86, a démontré le sens de «vivant»; ulantiš signifie par là «mort». Le mot est, en tant que thème en -i-, membre d'une déclinaison louvite, qui a vastement dépassé les limites dessinées par l'indo-européen commun: le -i- sert d'élargissement pour toute sorte d e thèmes consonantiques; ainsi apparant- «futur» devient en louvite apparanti-, tijamm- «terre» passe à tiiammi-, v. ci-dessous, etc. Notre mot sera donc élargi de *ulant-; et celui-ci a l'air d'un participe ou au moins d'un adjectif du type connu du hittite: hitt. akkant- «mort», part, du présent de akk- « mourir» ; maklant- «maigre», adj. en -ant-, de même irmalant- «malade», etc. Si ulant- est participe, on le déduira de ul-, thème verbal au sens de «périr», «mourir», donc au sens intrans, comme hitt. akkant-, ou bien on y verra un participe en -nt- au sens passif, dont la base verbale sera transitive, au sens de «faire périr, anéantir, tuer»; or il existe une racine indo-européenne qui montre les deux sens, le transitif et l' intransitif, réunis dans le même système: c'est *uel-(ə- «tuer» et «périr», à savoir dans hittite цаlh- «frapper, tuer», v. pruss. ūlint «lutter», en face de lait. vallessit «perierit», v. norr. valr «les cadavres sur le champ de bataille», tolkh. A αäl- «mourir», etc.;33 voir Pedersen, Tocharisch, p. 189.

  15. Smoking and renal function in people living with human immunodeficiency virus: a Danish nationwide cohort study

    Directory of Open Access Journals (Sweden)

    Ahlström MG

    2015-08-01

    Full Text Available Magnus Glindvad Ahlström,1 Bo Feldt-Rasmussen,2 Rebecca Legarth,1 Gitte Kronborg,3 Court Pedersen,4 Carsten Schade Larsen,5 Jan Gerstoft,1 Niels Obel1 1Department of Infectious Diseases, 2Department of Nephrology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, 3Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, 4Department of Infectious Diseases, Odense University Hospital, Odense, 5Department of Infectious Diseases, Aarhus University Hospital, Skejby, Aarhus, Denmark Introduction: Smoking is a main risk factor for morbidity and mortality in people living with human immunodeficiency virus (PLHIV, but its potential association with renal impairment remains to be established. Methods: We did a nationwide population-based cohort study in Danish PLHIV to evaluate the association between smoking status and 1 overall renal function and risk of chronic kidney disease (CKD, 2 risk of any renal replacement therapy (aRRT, and 3 mortality following aRRT. We calculated estimated creatinine clearance using the Cockcroft–Gault equation (CG-CrCl, and evaluated renal function graphically. We calculated cumulative incidence of CKD (defined as two consecutive CG-CrCls of ≤60 mL/min, ≥3 months apart and aRRT and used Cox regression models to calculate incidence rate ratios (IRRs for risk of CKD, aRRT, and mortality rate ratios (MRRs following aRRT. Results: From the Danish HIV Cohort Study, we identified 1,475 never smokers, 768 previous smokers, and 2,272 current smokers. During study period, we observed no association of smoking status with overall renal function. Previous and current smoking was not associated with increased risk of CKD (adjusted IRR: 1.1, 95% confidence interval [CI]: 0.7–1.7; adjusted IRR: 1.3, 95% CI: 0.9–1.8 or aRRT (adjusted IRR: 0.8, 95% CI: 0.4–1.7; adjusted IRR: 0.9, 95% CI: 0.5–1.7. Mortality following aRRT was high in PLHIV and increased in smokers vs never smokers (adjusted MRR: 3

  16. Chapter 8: Selective Stoichiometric and Catalytic Reactivity in the Confines of a Chiral Supramolecular Assembly

    Energy Technology Data Exchange (ETDEWEB)

    University of California, Berkeley; Lawrence Berkeley National Laboratory; Raymond, Kenneth; Pluth, Michael D.; Bergman, Robert G.; Raymond, Kenneth N.

    2007-09-27

    Nature uses enzymes to activate otherwise unreactive compounds in remarkable ways. For example, DNases are capable of hydrolyzing phosphate diester bonds in DNA within seconds,[1-3]--a reaction with an estimated half-life of 200 million years without an enzyme.[4] The fundamental features of enzyme catalysis have been much discussed over the last sixty years in an effort to explain the dramatic rate increases and high selectivities of enzymes. As early as 1946, Linus Pauling suggested that enzymes must preferentially recognize and stabilize the transition state over the ground state of a substrate.[5] Despite the intense study of enzymatic selectivity and ability to catalyze chemical reactions, the entire nature of enzyme-based catalysis is still poorly understood. For example, Houk and co-workers recently reported a survey of binding affinities in a wide variety of enzyme-ligand, enzyme-transition-state, and synthetic host-guest complexes and found that the average binding affinities were insufficient to generate many of the rate accelerations observed in biological systems.[6] Therefore, transition-state stabilization cannot be the sole contributor to the high reactivity and selectivity of enzymes, but rather, other forces must contribute to the activation of substrate molecules. Inspired by the efficiency and selectivity of Nature, synthetic chemists have admired the ability of enzymes to activate otherwise unreactive molecules in the confines of an active site. Although much less complex than the evolved active sites of enzymes, synthetic host molecules have been developed that can carry out complex reactions with their cavities. While progress has been made toward highly efficient and selective reactivity inside of synthetic hosts, the lofty goal of duplicating enzymes specificity remains.[7-9] Pioneered by Lehn, Cram, Pedersen, and Breslow, supramolecular chemistry has evolved well beyond the crown ethers and cryptands originally studied.[10-12] Despite the

  17. Dyslipidemia and cardiovascular disease risk profiles of patients attending an HIV treatment clinic in Harare, Zimbabwe

    Directory of Open Access Journals (Sweden)

    Zhou DT

    2015-05-01

    Full Text Available Danai Tavonga Zhou,1,2 Vitaris Kodogo,1 Kudzai Fortunate Vongai Chokuona,1 Exnevia Gomo,1 Olav Oektedalen,3 Babill Stray-Pedersen21Department of Medical Laboratory Sciences, College of Health Sciences, University of Zimbabwe, Avondale, Zimbabwe; 2Institute of Clinical Medicine, University in Oslo, Oslo University Hospital, Oslo, Norway; 3Department of Infectious Diseases, Oslo University Hospital, Oslo, NorwayAbstract: The chronic inflammation induced by human immunodeficiency virus (HIV contributes to increased risk of coronary heart disease (CHD in HIV-infected individuals. HIV-infected patients generally benefit from being treated with antiretroviral drugs, but some antiretroviral agents have side effects, such as dyslipidemia and hyperglycemia. There is general consensus that antiretroviral drugs induce a long-term risk of CHD, although the levels of that risk are somewhat controversial. The intention of this cross-sectional study was to describe the lipid profile and the long-term risk of CHD among HIV-positive outpatients at an HIV treatment clinic in Harare, Zimbabwe. Two hundred and fifteen patients were investigated (females n=165, mean age 39.8 years; males n=50; mean age 42.0 years. Thirty of the individuals were antiretroviral-naïve and 185 had been on antiretroviral therapy (ART for a mean 3.9±3.4 years. All participants had average lipid and glucose values within normal ranges, but there was a small difference between the ART and ART- for total cholesterol (TC and high-density lipoprotein (HDL.Those on a combination of D4T or ZDV/NVP/3TC and PI-based ART were on average oldest and had the highest TC levels. Framingham risk showed 1.4% prevalence of high CHD risk within the next ten years. After univariate analysis age, sex, TC/HDL ratio, HDL, economic earnings and systolic BP were associated with medium to high risk of CHD. After multivariate regression analysis and adjusting for age or sex only age, sex and economic earnings

  18. Fault structures in the focal area of the 2016 Kumamoto earthquake revealed by derivatives and structure parameters of a gravity gradient tensor

    Science.gov (United States)

    Hiramatsu, Y.; Matsumoto, N.; Sawada, A.

    2016-12-01

    We analyze gravity anomalies in the focal area of the 2016 Kumamoto earthquake, evaluate the continuity, segmentation and faulting type of the active fault zones, and discuss relationships between those features and the aftershock distribution. We compile the gravity data published by the Gravity Research Group in Southwest Japan (2001), the Geographical Survey Institute (2006), Yamamoto et al. (2011), Honda et al. (2012), and the Geological Survey of Japan, AIST (2013). We apply terrain corrections with 10 m DEM and a low-pass filter, then remove a linear trend to obtain Bouguer anomalies. We calculate the first horizontal derivative (HD), the first vertical derivative (VD), the normalized total horizontal derivative (TDX) (Cooper and Cowan, 2006), the dimensionality index (Di) (Beki and Pedersen, 2010), and dip angle (β) (Beki, 2013) from a gravity gradient tensor. The HD, VD and TDX show the existence of the continuous fault structure along the Futagawa fault zone, extending from the Uto peninsula to the Beppu Bay except Mt. Aso area. Aftershocks are distributed along this structural boundary from the confluence of the Futagawa and the Hinagu fault zones to the east end of the Aso volcano. The distribution of dip angle β along the Futagawa fault zone implies a normal faulting, which corresponds to the coseismic faulting estimated geologically and geomorphologically. We observe the S-shaped distribution of the Bouguer anomalies around the southern part of the Hinagu segment, indicating a right lateral faulting. The VD and TDX support the existence of the fault structure along the segment but it is not so clear. We can recognize no clear structural boundaries along the Takano-Shirahata segment. TDX implies the existence of a structural boundary with a NW-SE trend around the boundary between the Hinagu and Takano-Shirahata segments. The Di shows that this boundary has a 3D-like structure rather than a 2D-like one, suggesting the discontinuity of 2D-like fault

  19. Selective crystallization of cations with crown ethers; Selektive Kristallisation von Kationen mit Kronenethern

    Energy Technology Data Exchange (ETDEWEB)

    Heffels, Dennis Egidius

    2014-07-04

    structures can be assigned to general structure types already found by Pedersen, among them two silver compounds with the rather rare 2:3 type structure.

  20. Disturbance zonal and vertical plasma drifts in the Peruvian sector during solar minimum phases

    Science.gov (United States)

    Santos, A. M.; Abdu, M. A.; Souza, J. R.; Sobral, J. H. A.; Batista, I. S.

    2016-03-01

    In the present work, we investigate the behavior of the equatorial F region zonal plasma drifts over the Peruvian region under magnetically disturbed conditions during two solar minimum epochs, one of them being the recent prolonged solar activity minimum. The study utilizes the vertical and zonal components of the plasma drifts measured by the Jicamarca (11.95°S; 76.87°W) incoherent scatter radar during two events that occurred on 10 April 1997 and 24 June 2008 and model calculation of the zonal drift in a realistic ionosphere simulated by the Sheffield University Plasmasphere-Ionosphere Model-INPE. Two main points are focused: (1) the connection between electric fields and plasma drifts under prompt penetration electric field during a disturbed periods and (2) anomalous behavior of daytime zonal drift in the absence of any magnetic storm. A perfect anticorrelation between vertical and zonal drifts was observed during the night and in the initial and growth phases of the magnetic storm. For the first time, based on a realistic low-latitude ionosphere, we will show, on a detailed quantitative basis, that this anticorrelation is driven mainly by a vertical Hall electric field induced by the primary zonal electric field in the presence of an enhanced nighttime E region ionization. It is shown that an increase in the field line-integrated Hall-to-Pedersen conductivity ratio (∑H/∑P), which can arise from precipitation of energetic particles in the region of the South American Magnetic Anomaly, is capable of explaining the observed anticorrelation between the vertical and zonal plasma drifts. Evidence for the particle ionization is provided from the occurrence of anomalous sporadic E layers over the low-latitude station, Cachoeira Paulista (22.67°S; 44.9°W)—Brazil. It will also be shown that the zonal plasma drift reversal to eastward in the afternoon two hours earlier than its reference quiet time pattern is possibly caused by weakening of the zonal wind

  1. General method for calculating polarization electric fields produced by auroral Cowling mechanism and application examples

    Science.gov (United States)

    Vanhamäki, Heikki; Amm, Olaf; Fujii, Ryo; Yoshikawa, Aki; Ieda, Aki

    2013-04-01

    The Cowling mechanism is characterized by the generation of polarization space charges in the ionosphere in consequence of a partial or total blockage of FAC flowing between the ionosphere and the magnetosphere. Thus a secondary polarization electric field builds up in the ionosphere, which guarantees that the whole (primary + secondary) ionospheric current system is again in balance with the FAC. In the Earth's ionosphere the Cowling mechanism is long known to operate in the equatorial electrojet, and several studies indicate that it is important also in auroral current systems. We present a general method for calculate the secondary polarization electric field, when the ionospheric conductances, the primary (modeled) or the total (measured) electric field, and the Cowling efficiency are given. Here the Cowling efficiency is defined as the fraction of the divergent Hall current canceled by secondary Pedersen current. In contrast to previous studies, our approach is a general solution which is not limited to specific geometrical setups (like an auroral arc), and all parameters may have any kind of spatial dependence. The solution technique is based on spherical elementary current (vector) systems (SECS). This way, we avoid the need to specify explicit boundary conditions for the searched polarization electric field or its potential, which would be required if the problem was solved in a differential equation approach. Instead, we solve an algebraic matrix equation, for which the implicit boundary condition that the divergence of the polarization electric field vanishes outside our analysis area is sufficient. In order to illustrate the effect of Cowling mechanism on ionospheric current systems, we apply our method to two simple models of auroral electrodynamic situations: 1) a mesoscale strong conductance enhancement in the early morning sector within a relatively weak southward primary electric field, 2) a morning sector auroral arc with only a weak conductance

  2. Power plants 2009. Lectures

    International Nuclear Information System (INIS)

    2009-01-01

    Within the Annual Conference 2009 of the VGB PowerTech e.V. (Essen, Federal Republic of Germany) from 23rd to 25th May, 2009, in Lyon (France) the following lectures were held: (1) Electricity demand, consequences of the financial and economic crisis - Current overview 2020 for the EU-27 (Hans ten Berge); (2) Status and perspectives of the electricity generation mix in France (Bernard Dupraz); (3) European electricity grid - status and perspective (Dominique Maillard); (4) Technologies and acceptance in the European energy market (Gordon MacKerran); (5) EPR construction in Finland, China, France, (Claude Jaouen); (6) EPR Flamanville 3: A project on the path towards nuclear revival (Jacques Alary); (7) Worldwide nuclear Revival and acceptance (Luc Geraets); (8) An overview on the status of final disposal of radioactive wastes worldwide (Piet Zuidema); (9) Who needs pumped storage plants? PSP are partner to grid stability and renewable energies (Hans-Christoph Funke); (10) Sustainable use of water resources to generate electricity safely and efficiently (Patrick Tourasse); (11) The growth strategy of RWE Innogy - Role of RES in RWE strategy (Fritz Vahrenholt); (12) Solar technologies towards grid parity - key factors and timeframe (G. Gigliucci); (13) Overview on CCS technologies and results of Vattenfalls oxyfuel pilot plant (Philippe Paelinck); (14) Development perspectives of lignite-based IGCC-plants with CCS (Dietmar Keller); (15) Post combustion capture plants - concept and plant integration (Wolfgang Schreier); (16) CCS fossil power generation in a carbon constraint world (Daniel Hofmann); (17) CEZ group strategy in Central and South Eastern Europe (Jan Zizka); (18) Strategy and projects of DONG Energy (Jens Erik Pedersen); (19) E.ON coal-based power generation of the future - The highly efficient power plant and downstream separation of carbon dioxide (Gerhard Seibel); (20) Final sage of first supercritical 460 MW e l. CFB Boiler construction - firs

  3. Statistical properties of Joule heating rate, electric field and conductances at high latitudes

    Directory of Open Access Journals (Sweden)

    A. T. Aikio

    2009-07-01

    Full Text Available Statistical properties of Joule heating rate, electric field and conductances in the high latitude ionosphere are studied by a unique one-month measurement made by the EISCAT incoherent scatter radar in Tromsø (66.6 cgmlat from 6 March to 6 April 2006. The data are from the same season (close to vernal equinox and from similar sunspot conditions (about 1.5 years before the sunspot minimum providing an excellent set of data to study the MLT and Kp dependence of parameters with high temporal and spatial resolution.

    All the parameters show a clear MLT variation, which is different for low and high Kp conditions. Our results indicate that the response of morning sector conductances and conductance ratios to increased magnetic activity is stronger than that of the evening sector. The co-location of Pedersen conductance maximum and electric field maximum in the morning sector produces the largest Joule heating rates 03–05 MLT for Kp≥3. In the evening sector, a smaller maximum occurs at 18 MLT. Minimum Joule heating rates in the nightside are statistically observed at 23 MLT, which is the location of the electric Harang discontinuity.

    An important outcome of the paper are the fitted functions for the Joule heating rate as a function of electric field magnitude, separately for four MLT sectors and two activity levels (Kp<3 and Kp≥3. In addition to the squared electric field, the fit includes a linear term to study the possible anticorrelation or correlation between electric field and conductance. In the midday sector, positive correlation is found as well as in the morning sector for the high activity case. In the midnight and evening sectors, anticorrelation between electric field and conductance is obtained, i.e. high electric fields are associated with low conductances. This is expected to occur in the return current regions adjacent to

  4. Statistical properties of Joule heating rate, electric field and conductances at high latitudes

    Directory of Open Access Journals (Sweden)

    A. T. Aikio

    2009-07-01

    Full Text Available Statistical properties of Joule heating rate, electric field and conductances in the high latitude ionosphere are studied by a unique one-month measurement made by the EISCAT incoherent scatter radar in Tromsø (66.6 cgmlat from 6 March to 6 April 2006. The data are from the same season (close to vernal equinox and from similar sunspot conditions (about 1.5 years before the sunspot minimum providing an excellent set of data to study the MLT and Kp dependence of parameters with high temporal and spatial resolution. All the parameters show a clear MLT variation, which is different for low and high Kp conditions. Our results indicate that the response of morning sector conductances and conductance ratios to increased magnetic activity is stronger than that of the evening sector. The co-location of Pedersen conductance maximum and electric field maximum in the morning sector produces the largest Joule heating rates 03–05 MLT for Kp≥3. In the evening sector, a smaller maximum occurs at 18 MLT. Minimum Joule heating rates in the nightside are statistically observed at 23 MLT, which is the location of the electric Harang discontinuity. An important outcome of the paper are the fitted functions for the Joule heating rate as a function of electric field magnitude, separately for four MLT sectors and two activity levels (Kp<3 and Kp≥3. In addition to the squared electric field, the fit includes a linear term to study the possible anticorrelation or correlation between electric field and conductance. In the midday sector, positive correlation is found as well as in the morning sector for the high activity case. In the midnight and evening sectors, anticorrelation between electric field and conductance is obtained, i.e. high electric fields are associated with low conductances. This is expected to occur in the return current regions adjacent to auroral arcs as a result of ionosphere-magnetosphere coupling, as discussed by Aikio et al. (2004 In

  5. Effects of tectonics and large scale climatic changes on the evolutionary history of Hyalomma ticks.

    Science.gov (United States)

    Sands, Arthur F; Apanaskevich, Dmitry A; Matthee, Sonja; Horak, Ivan G; Harrison, Alan; Karim, Shahid; Mohammad, Mohammad K; Mumcuoglu, Kosta Y; Rajakaruna, Rupika S; Santos-Silva, Maria M; Matthee, Conrad A

    2017-09-01

    Hyalomma Koch, 1844 are ixodid ticks that infest mammals, birds and reptiles, to which 27 recognized species occur across the Afrotropical, Palearctic and Oriental regions. Despite their medical and veterinary importance, the evolutionary history of the group is enigmatic. To investigate various taxonomic hypotheses based on morphology, and also some of the mechanisms involved in the diversification of the genus, we sequenced and analysed data derived from two mtDNA fragments, three nuclear DNA genes and 47 morphological characters. Bayesian and Parsimony analyses based on the combined data (2242 characters for 84 taxa) provided maximum resolution and strongly supported the monophyly of Hyalomma and the subgenus Euhyalomma Filippova, 1984 (including H. punt Hoogstraal, Kaiser and Pedersen, 1969). A predicted close evolutionary association was found between morphologically similar H. dromedarii Koch, 1844, H. somalicum Tonelli Rondelli, 1935, H. impeltatum Schulze and Schlottke, 1929 and H. punt, and together they form a sister lineage to H. asiaticum Schulze and Schlottke, 1929, H. schulzei Olenev, 1931 and H. scupense Schulze, 1919. Congruent with morphological suggestions, H. anatolicum Koch, 1844, H. excavatum Koch, 1844 and H. lusitanicum Koch, 1844 form a clade and so also H. glabrum Delpy, 1949, H. marginatum Koch, 1844, H. turanicum Pomerantzev, 1946 and H. rufipes Koch, 1844. Wide scale continental sampling revealed cryptic divergences within African H. truncatum Koch, 1844 and H. rufipes and suggested that the taxonomy of these lineages is in need of a revision. The most basal lineages in Hyalomma represent taxa currently confined to Eurasia and molecular clock estimates suggest that members of the genus started to diverge approximately 36.25 million years ago (Mya). The early diversification event coincides well with the collision of the Indian and Eurasian Plates, an event that was also characterized by large scale faunal turnover in the region. Using S

  6. A Study on the Ionosphere and Thermosphere Interaction Based on NCAR-TIEGCM: Dependence of the Interplanetary Magnetic Field (IMF on the Momentum Forcing in the High-Latitude Lower Thermosphere

    Directory of Open Access Journals (Sweden)

    Young-Sil Kwak

    2005-06-01

    Full Text Available To understand the physical processes that control the high-latitude lower thermospheric dynamics, we quantify the forces that are mainly responsible for maintaining the high-latitude lower thermospheric wind system with the aid of the National Center for Atmospheric Research Thermosphere-Ionosphere Electrodynamics General Circulation Model (NCAR-TIEGCM. Momentum forcing is statistically analyzed in magnetic coordinates, and its behavior with respect to the magnitude and orientation of the interplanetary magnetic field (IMF is further examined. By subtracting the values with zero IMF from those with non-zero IMF, we obtained the difference winds and forces in the high-latitude lower thermosphere( 0.8 |bar{B}_z| or negative(B_y 0.3125 |bar{B}_y| or negative(B_z 125 km the primary forces that determine the variations of the neutral winds are the pressure gradient, Coriolis and rotational Pedersen ion drag forces; however, at various locations and times significant contributions can be made by the horizontal advection force. On the other hand, at lower altitudes(108-125 km the pressure gradient, Coriolis and non-rotational Hall ion drag forces determine the variations of the neutral winds. At lower altitudes(<108 km it tends to generate a geostrophic motion with the balance between the pressure gradient and Coriolis forces. The northward component of IMF bar{B}_y-dependent average momentum forces act more significantly on the neutral motion except for the ion drag. At lower altitudes(108-125 km for negative IMF-bar{B}_y condition the ion drag force tends to generate a warm clockwise circulation with downward vertical motion associated with the adiabatic compress heating in the polar cap region. For positive IMF-bar{B}_y condition it tends to generate a cold anticlockwise circulation with upward vertical motion associated with the adiabatic expansion cooling in the polar cap region. For negative IMF-bar{B}_z the ion drag force tends to generate a

  7. Antidepressant exposure in pregnancy and risk of autism spectrum disorders

    Directory of Open Access Journals (Sweden)

    Sørensen MJ

    2013-11-01

    Full Text Available Merete Juul Sørensen,1 Therese Koops Grønborg,2 Jakob Christensen,3,4 Erik Thorlund Parner,2 Mogens Vestergaard,5,6 Diana Schendel,7 Lars Henning Pedersen8,9 1Regional Centre of Child and Adolescent Psychiatry, Aarhus University Hospital, Risskov, Denmark; 2Department of Public Health, Section of Biostatistics, Aarhus University, Aarhus, Denmark; 3Department of Neurology, Aarhus University Hospital, Aarhus, Denmark; 4Department of Clinical Pharmacology, 5Department of Public Health, Section of General Practice, 6Research unit for General Practice, Aarhus University, Aarhus, Denmark; 7Centers for Disease Control and Prevention, Atlanta, GA, USA; 8Danish Epidemiological Science Centre, Institute of Public Health, 9Department of Obstetrics and Gynecology, Institute of Clinical Medicine, Aarhus University, Aarhus, Denmark Background: Both the use of antidepressant medication during pregnancy and the prevalence of autism spectrum disorder have increased during recent years. A causal link has recently been suggested, but the association may be confounded by the underlying indication for antidepressant use. We investigated the association between maternal use of antidepressant medication in pregnancy and autism, controlling for potential confounding factors. Methods: We identified all children born alive in Denmark 1996–2006 (n=668,468 and their parents in the Danish Civil Registration System. We obtained information on the mother's prescriptions filled during pregnancy from the Danish National Prescription Registry, and on diagnoses of autism spectrum disorders in the children and diagnoses of psychiatric disorders in the parents from the Danish Psychiatric Central Register. In a cohort analysis, we estimated hazard ratios of autism spectrum disorders in children exposed to antidepressant medication during pregnancy compared with children who were not exposed, using Cox proportional hazards regression analysis. Furthermore, we estimated the risk

  8. Improving Neuromuscular Monitoring and Reducing Residual Neuromuscular Blockade With E-Learning: Protocol for the Multicenter Interrupted Time Series INVERT Study.

    Science.gov (United States)

    Thomsen, Jakob Louis Demant; Mathiesen, Ole; Hägi-Pedersen, Daniel; Skovgaard, Lene Theil; Østergaard, Doris; Engbaek, Jens; Gätke, Mona Ring

    2017-10-06

    -learning module was implemented in 6 anesthesia departments on 21 November 2016. Currently, we are collecting postintervention data. The final dataset will include data from more than 10,000 anesthesia procedures. We expect to publish the results in late 2017 or early 2018. With a dataset consisting of thousands of general anesthesia procedures, the INVERT study will assess whether an e-learning module can increase anesthetists' use of neuromuscular monitoring. Clinicaltrials.gov NCT02925143; https://clinicaltrials.gov/ct2/show/NCT02925143 (Archived by WebCite® at http://www.webcitation.org/6s50iTV2x). ©Jakob Louis Demant Thomsen, Ole Mathiesen, Daniel Hägi-Pedersen, Lene Theil Skovgaard, Doris Østergaard, Jens Engbaek, Mona Ring Gätke. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 06.10.2017.

  9. Androgens and Psychosocial Factors Related to Sexual Dysfunctions in Premenopausal Women∗: ∗2016 ISSM Female Sexual Dysfunction Prize.

    Science.gov (United States)

    Wåhlin-Jacobsen, Sarah; Kristensen, Ellids; Pedersen, Anette Tønnes; Laessøe, Nanna Cassandra; Cohen, Arieh S; Hougaard, David M; Lundqvist, Marika; Giraldi, Annamaria

    2017-03-01

    The female sexual response is complex and influenced by several biological, psychological, and social factors. Testosterone is believed to modulate a woman's sexual response and desire, because low levels are considered a risk factor for impaired sexual function, but previous studies have been inconclusive. To investigate how androgen levels and psychosocial factors are associated with female sexual dysfunction (FSD), including hypoactive sexual desire disorder (HSDD). The cross-sectional study included 428 premenopausal women 19 to 58 years old who completed a questionnaire on psychosocial factors and had blood sampled at days 6 to 10 in their menstrual cycle. Logistic regression models were built to test the association among hormone levels, psychosocial factors, and sexual end points. Five different sexual end points were measured using the Female Sexual Function Index and the Female Sexual Distress Scale: impaired sexual function, sexual distress, FSD, low sexual desire, and HSDD. Serum levels of total and free testosterone, androstenedione, dehydroepiandrosterone sulfate, and androsterone glucuronide were analyzed using mass spectrometry. After adjusting for psychosocial factors, women with low sexual desire had significantly lower mean levels of free testosterone and androstenedione compared with women without low sexual desire. None of the androgens were associated with FSD in general or with HSDD in particular. Relationship duration longer than 2 years and mild depressive symptoms increased the risk of having all the sexual end points, including FSD in general and HSDD in particular in multivariate analyses. In this large cross-sectional study, low sexual desire was significantly associated with levels of free testosterone and androstenedione, but FSD in general and HSDD in particular were not associated with androgen levels. Length of relationship and depression were associated with FSD including HSDD. Wåhlin-Jacobsen S, Kristensen E, Tønnes Pedersen A

  10. Advancement of DOE's EnergyPlus Building Energy Simulation Payment

    Energy Technology Data Exchange (ETDEWEB)

    Gu, Lixing [Florida Solar Energy Center, Cocoa, FL (United States); Shirey, Don [Florida Solar Energy Center, Cocoa, FL (United States); Raustad, Richard [Florida Solar Energy Center, Cocoa, FL (United States); Nigusse, Bereket [Florida Solar Energy Center, Cocoa, FL (United States); Sharma, Chandan [Florida Solar Energy Center, Cocoa, FL (United States); Lawrie, Linda [DHL Consulting, Bonn (Germany); Strand, Rick [Univ. of Illinois, Champaign, IL (United States); Pedersen, Curt [COPA, Panama City (Panama); Fisher, Dan [Oklahoma State Univ., Stillwater, OK (United States); Lee, Edwin [Oklahoma State Univ., Stillwater, OK (United States); Witte, Mike [GARD Analytics, Arlington Heights, IL (United States); Glazer, Jason [GARD Analytics, Arlington Heights, IL (United States); Barnaby, Chip [Wrightsoft, Lexington, MA (United States)

    2011-09-30

    EnergyPlus{sup TM} is a new generation computer software analysis tool that has been developed, tested, and commercialized to support DOE's Building Technologies (BT) Program in terms of whole-building, component, and systems R&D (http://www.energyplus.gov). It is also being used to support evaluation and decision making of zero energy building (ZEB) energy efficiency and supply technologies during new building design and existing building retrofits. The 5-year project was managed by the National Energy Technology Laboratory and was divided into 5 budget period between 2006 and 2011. During the project period, 11 versions of EnergyPlus were released. This report summarizes work performed by an EnergyPlus development team led by the University of Central Florida's Florida Solar Energy Center (UCF/FSEC). The team members consist of DHL Consulting, C. O. Pedersen Associates, University of Illinois at Urbana-Champaign, Oklahoma State University, GARD Analytics, Inc., and WrightSoft Corporation. The project tasks involved new feature development, testing and validation, user support and training, and general EnergyPlus support. The team developed 146 new features during the 5-year period to advance the EnergyPlus capabilities. Annual contributions of new features are 7 in budget period 1, 19 in period 2, 36 in period 3, 41 in period 4, and 43 in period 5, respectively. The testing and validation task focused on running test suite and publishing report, developing new IEA test suite cases, testing and validating new source code, addressing change requests, and creating and testing installation package. The user support and training task provided support for users and interface developers, and organized and taught workshops. The general support task involved upgrading StarTeam (team sharing) software and updating existing utility software. The project met the DOE objectives and completed all tasks successfully. Although the EnergyPlus software was enhanced

  11. Prevalence and Predicting Factors for Commonly Neglected Sexual Side Effects to External-Beam Radiation Therapy for Prostate Cancer.

    Science.gov (United States)

    Frey, Anders; Pedersen, Christian; Lindberg, Henriette; Bisbjerg, Rasmus; Sønksen, Jens; Fode, Mikkel

    2017-04-01

    pursue. Frey A, Pedersen C, Lindberg H, et al. Prevalence and Predicting Factors for Commonly Neglected Sexual Side Effects to External-Beam Radiation Therapy for Prostate Cancer. J Sex Med 2017;14:558-565. Copyright © 2017 International Society for Sexual Medicine. Published by Elsevier Inc. All rights reserved.

  12. Prenatal Ambient Air Pollution, Placental Mitochondrial DNA Content, and Birth Weight in the INMA (Spain) and ENVIRONAGE (Belgium) Birth Cohorts

    Science.gov (United States)

    Clemente, Diana B.P.; Casas, Maribel; Vilahur, Nadia; Begiristain, Haizea; Bustamante, Mariona; Carsin, Anne-Elie; Fernández, Mariana F.; Fierens, Frans; Gyselaers, Wilfried; Iñiguez, Carmen; Janssen, Bram G.; Lefebvre, Wouter; Llop, Sabrina; Olea, Nicolás; Pedersen, Marie; Pieters, Nicky; Santa Marina, Loreto; Souto, Ana; Tardón, Adonina; Vanpoucke, Charlotte; Vrijheid, Martine; Sunyer, Jordi; Nawrot, Tim S.

    2015-01-01

    , Lefebvre W, Llop S, Olea N, Pedersen M, Pieters N, Santa Marina L, Souto A, Tardón A, Vanpoucke C, Vrijheid M, Sunyer J, Nawrot TS. 2016. Prenatal ambient air pollution, placental mitochondrial DNA content, and birth weight in the INMA (Spain) and ENVIRONAGE (Belgium) birth cohorts. Environ Health Perspect 124:659–665; http://dx.doi.org/10.1289/ehp.1408981 PMID:26317635

  13. Acromegaly according to the Danish National Registry of Patients: how valid are ICD diagnoses and how do patterns of registration affect the accuracy of registry data?

    Directory of Open Access Journals (Sweden)

    Dal J

    2014-09-01

    Full Text Available Jakob Dal,1 Nikolaj Skou,1 Eigil Husted Nielsen,2 Jens Otto Lunde Jørgensen,1 Lars Pedersen3 1Department of Endocrinology, Aarhus University Hospital, Aarhus, 2Department of Endocrinology, Aalborg University Hospital, Aalborg, 3Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark Background: The incidence of acromegaly is uncertain, since population-based studies are few. In the absence of a specific acromegaly registry, the Danish National Registry of Patients (DNRP becomes a potential source of data for studying the epidemiology of acromegaly, by linking all hospital discharge diagnoses to the personal identification numbers of individual Danish inhabitants. The validity of the DNRP with respect to acromegaly, however, remains to be tested. The aim of this study was to validate the International Classification of Diseases (ICD codes for acromegaly (ICD-8: 25300, 25301. ICD-10: E22.0 as used in the DNRP, and to assess the influence of various registration patterns on the accuracy of registry data. Methods: We identified patients registered with ICD codes for the diagnosis of acromegaly or other pituitary disorders during the period 1991–2009. Data on the institutional origin of each registration and the number of relevant DNRP registrations were recorded, and systematic patient chart reviews were performed to confirm the diagnosis. Results: In total, 110 cases of acromegaly were confirmed, compared with 275 registered cases, yielding a positive predictive value (PPV of 40%. When restricting the search to the regional highly specialized department of endocrinology, the PPV increased to 53% with no loss of cases with confirmed acromegaly. With a requirement of at least one, two, or three DNRP registrations, the PPV increased, but with a concurrent loss of confirmed cases. Conclusion: The DNRP seems to be a useful source for identifying new cases of acromegaly, especially when restricting the search to a relevant

  14. Letter from Stockholm.

    Science.gov (United States)

    Johansson, Per Magnus

    2015-04-01

    Some of the ideas of Sigmund Freud were preceded in a literary form by the Swedish writer August Strindberg in the late 19th century. Psychoanalysis itself was introduced in Sweden about a decade into the 20th century by two rivalling pioneers, the doctors Emanuel af Geijerstam and Poul Bjerre. After a slow start, the Danish-Norwegian Psychoanalytical Society and the Finnish-Swedish Psychoanalytical Society were formed in 1934 in Stockholm. The same year, Ericastiftelsen [The Erica Foundation], a psychotherapeutic clinic for children, was founded by Hanna Bratt. Five years later, in 1939, also in Stockholm, the organization that was to become St. Lukasstiftelsen [The Saint Luke's Foundation] was founded. It has been, and still is, an association that has trained psychodynamic psychotherapists, with a focus on existential, religious and philosophical questions. Today, St. Luke's tries to be up-dated from an academic standpoint. During the Second World War, several important psychoanalysts came to Sweden, for example René de Monchy, Lajos and Edith Székely, and Stefi Pedersen. Ola Andersson's doctoral dissertation ("Studies in the Prehistory of Psychoanalysis", 1962) and the historian Gunnar Brandell's essay ("Freud, a Man of His Century", 1961) have had an international impact. In the last two decades, an authorized and carefully edited translation of Freud's collected works has been published by Natur och Kultur, and the history of psychoanalysis in Sweden has been written at the University of Gothenburg. As a result of a recent interest in the work of Jacques Lacan, and French psychoanalysis, philosophy and literature, the journal Psykoanalytisk Tid/Skrift was founded in 2002, in Gothenburg. Since 2011 the journal is called Arche. The largest organized group of psychoanalysts in Sweden today is the Swedish Psychoanalytical Association (SPAF), which has around 225 members. Since 2008, it no longer has the right to license psychotherapists, a situation which

  15. Le grammaire du Français et son historiographie: appréhensions, à deux siècles de distance d'in objet de débats

    Directory of Open Access Journals (Sweden)

    Pierre Swiggers

    2015-08-01

    Full Text Available Dans cet article, consacré àl 'historiographie de la grammaire française, on abordera d'abord le problème de la définition du champ de l'histoire (ou de l'historiographie de la grammaire française (et de la linguistique française. La deuxième partie du texte sera consacrée à un problème central de l 'epistémologie historique de la grammaire française: celui de la "récurrence du fait historique ", problème que je voudrais analyser à travers un cas concret, celui de l 'accueil fait à la grammaire de l 'Académie. L'historiographie de la grammaire/de la linguistique: la question de l'objet Ona tentéde concevoir et, parfois, de définir (ou d'expliciter l'historiographie de la grammaire/linguistique cornme étant dans un rapport d'iconicité partielle avec un objet appelé "l'histoire de la linguistique". Une telle attitude permet d'éluder la difficulté de devoir définir l'objet ou le domaine de cette discipline. Que cet objet ne soit guère donné d'avance, cela ressort déjà de l'histoire mȇme de l'historiographie de la linguistique: il suffira de comparer à ce propos des travaux cornme ceux de Thomsen (1902 et de Pedersen (1916, 1924 à ceux de Robins (19792 ou de Mounin (1967. En fait, cela ne doit guère nous étonner: cornme l'historiographie de la linguistique est une représentation de connaissances à propos de l 'histoire, il est inéluctable que la notion de son objet varie, du moins dans son extension, dans la mesure où les connaissances à propos de l 'histoire de la linguistique se sont élargies, enrichies ou modifiées.

  16. Cama-de-frango em mono e policultivo de fáfia com cravo-de-defunto e manjericão Poultry manure in mono and intercrop of Brazilian ginseng with marigold and basil

    Directory of Open Access Journals (Sweden)

    Valdenise C Barboza

    2010-09-01

    Full Text Available O experimento foi conduzido em campo da Universidade Federal da Grande Dourados (UFGD, em Dourados-MS, de março de 2005 a setembro de 2006, em Latossolo Vermelho distroférrico. O objetivo foi avaliar a produção da Pfaffia glomerata (Spreng Pedersen (fáfia em monocultivo e os policultivos com Tagetes erecta L. (cravo-de-defunto e Ocimum basilicum L. (manjericão, sem e com incorporação de cama-de-frango semidecomposta. Os fatores em estudo foram a fáfia (F, o cravo-de-defunto (C e o manjericão (M em monocultivos e os policultivos com duas fileiras de fáfia e três de cravo (F2C3 e duas fileiras de fáfia e três de manjericão (F2M3, todos sem e com incorporação ao solo de cama-de-frango de corte semidecomposta. Os dez tratamentos foram arranjados no delineamento blocos casualizados, com quatro repetições. A produção de massa fresca e seca da parte aérea da fáfia foi maior (13,22 t ha-1 e 4,39 t ha-1, respectivamente em monocultivo, independente do uso da cama-de-frango. Por outro lado, nenhum dos tratamentos influenciou a massa fresca e seca e o número de raízes da fáfia, que foram, em média, de 10,02 e 2,07 t ha-1 e 417.916 raízes ha-1, respectivamente. O diâmetro das raízes foi maior (23,5 mm no policultivo com o manjericão. As produções de massas frescas e secas dos capítulos florais do cravo-de-defunto foram maiores (14,28 t ha-1e 1,278 t ha-1, respectivamente no policultivo com a fáfia, mas apenas a produção de massa fresca dos capítulos foi maior (14,17 t ha-1 com o uso da cama-de-frango. A produção de parte aérea do manjericão foram maiores (52,91 t ha-1 no policultivo, independente com qual espécie; porém, não foi influenciada pelo uso da cama-de-frango. A razão de área equivalente (RAE para o policultivo da fáfia com o cravo-de-defunto foi de 2,15 com cama-de-frango e de 1,99 sem cama e com o manjericão, foi 2,44 com cama e de 3,08 sem cama. Como os valores foram maiores que 1,0, indicam que

  17. Magnetotelluric investigation of the Toender area, Denmark. ALTKUL project report part 2

    Energy Technology Data Exchange (ETDEWEB)

    Rasmussen, T.M.; Thorning, L. [GEUS, Copenhagen (Denmark); Pedersen, L.B.; Shan, C. [Uppsala Univ., Dept. of Earth Sciences, Uppsala (Sweden)

    2012-10-15

    hydrocarbons in the Toender area. The resistivity variations clearly reflect the presence of salt tectonics in the survey area. Another achievement from the test is the information on electromagnetic noise sources. The noise in the survey area was highly variable both spatially and with time. At some MT stations high quality data could be obtained. Other MT stations did not provide data of sufficiently quality to be included in the modelling. Some tentative comments with respect to interpretation of the acquired MT data are provided. We do not enter into an in-depth interpretation of the data and derived model, but we conclude that the MT data provide valuable information on the regional variations of resistivity. A number of anomalies are evident which point to significant variations in resistivity laterally. Some inconsistencies in relation to information from deep wells are noted with respect to depth to stratigraphic units. This is particularly the case at the location of the Borg-1 well. The salt pillow around at Toender is mapped well by the MT data. The reporting of the test is structured as follows: after a short introduction (with some basic information on MT for readers unfamiliar with the method) follows the report by L.B. Pedersen and J. Shan, Uppsala University, which represents the core of the test. It includes a description of field work, noise conditions and data quality, data processing techniques and modelling. The report by Pedersen and Shan and accompanying appendix is included as chapter 3 in this report. The last part of this report places the modelling results in context with geological information and other geophysical data publically available from the survey area. The purpose of this last part of the report is to provide information and considerations useful for further interpretation on the acquired new data. A section on the geology of the area is included with some key references and finally, another section includes displays of the model derived

  18. 海外專業志工服務:以雅加達臺灣國際學校成長營為例International Volunteerism Based on Professional Service: Summer Camps at Jakarta Taiwan International School

    Directory of Open Access Journals (Sweden)

    危芷芬(通訊作者)Chih-Fen Wei

    2012-09-01

    Full Text Available 多元文化諮商(multicultural counseling)是近年來諮商專業領域中最重要的議題之一(Sue & Sue, 2003),甚至被視為是心理學的第四勢力(Pedersen, 1991)。海外專業志工服務不僅可實踐專業於志工服務,亦能培育具備多元文化諮商能力的專業助人工作者。本研究以臺北市立教育大學心理與諮商學系的海外專業志工課程方案為例,說明課程方案發展的歷程並分析此課程方案如何提升志工的國際視野與公民責任感。臺北市立教育大學心理與諮商學系師生於2010年及2011年兩度前往雅加達臺灣國際學校,舉行EQ心理成長營及生涯成長營。課程設計除了符合學校定位與教育學院願景之外,也期能培養學生具備團隊合作精神、創新思考、心理專業倫理思辨與實踐、文化尊重與社會關懷之基本素養。海外志工服務與大四專業實習課程結合,融合輔導原理與實務、心理與教育測驗、諮商理論與技術、團體輔導、諮商技巧、生涯發展與輔導等課程,其成效包括:一、增進志工服務學生對於跨文化諮商的專業意識;二、增進志工服務學生對情緒教育、生涯規劃及生命教育的瞭解;三、增進學生設計、帶領營隊及跨文化服務輔導的能力;四、開拓學生之國際視野,培養世界公民責任感;五、增進學生獨立能力與服務熱忱。最後,本研究提出對於未來海外專業志工服務之建議包括:提供海外學校輔導資源、積極鼓勵國內外專業心理衛生服務及增加大學生海外服務機會。Multicultural counseling is regarded as one of the most important issues in counseling (Sue & Sue, 2003. It’s even called the fourth force in psychology (Pedersen, 1991. The international volunteerism not only put profession into practice, but also paved the road for training of multicultural counseling. EQ camp and

  19. Cosmological Gamma-Ray Bursts and Hypernovae Conclusively Linked

    Science.gov (United States)

    2003-06-01

    with the UVES spectrograph at the 8.2-m VLT KUEYEN telescope at the ESO Paranal Observatory (Chile). The corresponding distance is about 2,650 million light-years. This is the nearest normal GRB ever detected, therefore providing the long-awaited opportunity to test the many hypotheses and models which have been proposed since the discovery of the first GRBs in the late 1960's. With this specific aim, the ESO-lead team of astronomers [1] now turned to two other powerful instruments at the ESO Very Large Telescope (VLT), the multi-mode FORS1 and FORS2 camera/spectrographs. Over a period of one month, until May 1, 2003, spectra of the fading object were obtained at regular rate, securing a unique set of observational data that documents the physical changes in the remote object in unsurpassed detail. The hypernova connection Based on a careful study of these spectra, the astronomers are now presenting their interpretation of the GRB 030329 event in a research paper appearing in the international journal "Nature" on Thursday, June 19. Under the prosaic title "A very energetic supernova associated with the gamma-ray burst of 29 March 2003", no less than 27 authors from 17 research institutes, headed by Danish astronomer Jens Hjorth conclude that there is now irrefutable evidence of a direct connection between the GRB and the "hypernova" explosion of a very massive, highly evolved star. This is based on the gradual "emergence" with time of a supernova-type spectrum, revealing the extremely violent explosion of a star. With velocities well in excess of 30,000 km/sec (i.e., over 10% of the velocity of light), the ejected material is moving at record speed, testifying to the enormous power of the explosion. Hypernovae are rare events and they are probably caused by explosion of stars of the so-called "Wolf-Rayet" type [4]. These WR-stars were originally formed with a mass above 25 solar masses and consisted mostly of hydrogen. Now in their WR-phase, having stripped themselves

  20. Genetic dissection of bioenerrgy traits in sorghum

    Energy Technology Data Exchange (ETDEWEB)

    Vermerris, Wilfred; Kresovich, Stephen; Murray, Seth; Pedersen, Jeffery; Rooney, William; Sattler, Scott.

    2012-06-15

    project is acknowledged 1) Vermerris W, Saballos A (2012) Genetic enhancement of sorghum for biomass utilization. In Paterson, A. (Ed.) Genetics and Genomics of the Saccharinae, Springer, New York, NY. pp. 391-428. 2) Felderhoff T, Murray SC, Klein PE, Sharma A, Hamblin MT, Kresovich S, Vermerris W, Rooney, WL (2012) QTLs for energy-related traits in a sweet x grain sorghum [Sorghum bicolor (L.) Moench] mapping population. Crop Science 52: 2040-2049. 3) Sattler SE, Palmer NA, Saballos A, Greene AM, Xin Z, Sarath G, Vermerris W, Pedersen JF (2012) Identification and characterization of four missense mutations in Brown midrib12 (Bmr12), the caffeic acid O-methyltranferase (COMT) of sorghum. BioEnergy Research (in press) DOI 10.1007/s12155-012-9197-z 4) Saballos A, Sattler S, Sanchez E, Foster TP, Xin Z, Kang CH, Pedersen J, Vermerris W (2012). Brown midrib2 encodes the major 4-coumarate:CoA ligase involved in lignin biosynthesis in sorghum (Sorghum bicolor (L.) Moench). The Plant Journal 70: 818-830. doi: 10.1111/j.1365-313X.2012.04933. 5) Vermerris, W (2011) Survey of genomics approaches to improve bioenergy traits in maize, sorghum and sugarcane. Journal of Integrative Plant Biology 53: 105-119 6) Saballos A, Ejeta G, Sanchez E, Kang CH, Vermerris W (2009) A genome-wide analysis of the cinnamyl alcohol dehydrogenase family in sorghum [Sorghum bicolor (L.) Moench] identifies SbCAD2 as the Brown midrib6 gene. Genetics 181: 783-795. 7) Saballos A, Vermerris W, Rivera L, Ejeta G (2008) Allelic association, chemical characterization and saccharification properties of brown midrib mutants of sorghum (Sorghum bicolor (L.) Moench). BioEnergy Research 2: 193-204 8) Felderhoff TJ. (2012) QTLs for energy related traits in a sweet x grain RIL sorghum [Sorghum bicolor (L.) Moench] population. M.S. Thesis, Texas A&M University. Publications in preparation (tentative titles) 9) Felderhoff T, Murray SC, Klein PE, Sharma A, Hamblin MT, Kresovich S, Vermerris W, Rooney, WL (2013) QTLs for

  1. Adaptation response surfaces from an ensemble of wheat projections under climate change in Europe

    Science.gov (United States)

    Ruiz-Ramos, Margarita; Ferrise, Roberto

    2016-04-01

    preliminary ARSs show some adaptation options allow recover up to ca. 2000 kg/ha. Compared to the historical yields recorded at Lleida province (2550 kg/ha in 1981-2010) our results indicate that adaptation is feasible and may help to reduce detrimental effects of CC. Our analysis evaluates if the explored adaptations fulfill the biophysical requirements to become a practical adaptive solution. This study exemplifies how adaptation options and their impacts can be analyzed, evaluated and communicated in a context of high regional uncertainty for current and future conditions and for short to long-term perspective. This work was funded by MACSUR project within FACCE-JPI. References Abeledo, L.G., R. Savin and G.A. Slafer (2008). European Journal of Agronomy 28:541-550. Cartelle, J., A. Pedró, R. Savin, G.A. Slafer (2006) European Journal of Agronomy 25:365-371. Pirttioja, N., T. Carter, S. Fronzek, M. Bindi, H. Hoffmann, T. Palosuo, M. Ruiz-Ramos, F. Tao, M. Acutis, S. Asseng, P. Baranowski, B. Basso, P. Bodin, S. Buis, D. Cammarano, P. Deligios, M.-F. Destain, B. Dumont, R. Ewert, R. Ferrise, L. François, T. Gaiser, P. Hlavinka, I. Jacquemin, K.C. Kersebaum, C. Kollas, J. Krzyszczak, I.J. Lorite, J. Minet, M.I. Minguez, M. Montesino, M. Moriondo, C. Müller, C. Nendel, I. Öztürk, A. Perego, A. Rodríguez, A.C. Ruane, F. Ruget, M. Sanna, M.A. Semenov, C. Slawinski, P. Stratonovitch, I. Supit, K. Waha, E. Wang, L. Wu, Z. Zhao, and R.P. Rötter, 2015: A crop model ensemble analysis of temperature and precipitation effects on wheat yield across a European transect using impact response surfaces. Clim. Res., 65, 87-105, doi:10.3354/cr01322. IRS2 TEAM: Alfredo Rodríguez(1), Ignacio J. Lorite(3), Fulu Tao(4), Nina Pirttioja(5), Stefan Fronzek(5), Taru Palosuo(4), Timothy R. Carter(5), Marco Bindi(2), Jukka G Höhn(4), Kurt Christian Kersebaum(6), Miroslav Trnka(7,8), Holger Hoffmann(9), Piotr Baranowski(10), Samuel Buis(11), Davide Cammarano(12), Yi Chen(13,4), Paola Deligios

  2. Publishing high-quality climate data on the semantic web

    Science.gov (United States)

    Woolf, Andrew; Haller, Armin; Lefort, Laurent; Taylor, Kerry

    2013-04-01

    temperature dataset, Australian Climate Observations Reference Network - Surface Air Temperature (ACORN-SAT) [BoM, 2012b]. This dataset contains daily homogenised surface temperature observations for 112 locations around Australia, dating back to 1910. An ontology for the dataset was developed [Lefort et. al., 2012], based on the existing Semantic Sensor Network ontology [Compton et. al., 2012] and the W3C RDF Data Cube vocabulary [W3C, 2012]. Additional vocabularies were developed, e.g. for BoM weather stations and rainfall districts. The dataset was converted to RDF and loaded into an RDF triplestore. The Linked-Data API (http://code.google.com/p/linked-data-api) was used to configure specific URI query patterns (e.g. for observation timeseries slices by station), and a SPARQL endpoint was provided for direct querying. In addition, some demonstration 'mash-ups' were developed, providing an interactive browser-based interface to the temperature timeseries. References [Berners-Lee et. al., 2001] Tim Berners-Lee, James Hendler and Ora Lassila (2001), "The Semantic Web", Scientific American, May 2001. [Berners-Lee, 2006] Tim Berners-Lee (2006), "Linked Data - Design Issues", W3C [http://www.w3.org/DesignIssues/LinkedData.html] [BoM, 2012a] Bureau of Meteorology (2012), "Environmental information" [http://www.bom.gov.au/environment/] [BoM, 2012b] Bureau of Meteorology (2012), "Australian Climate Observations Reference Network - Surface Air Temperature" [http://www.bom.gov.au/climate/change/acorn-sat/] [Compton et. al., 2012] Michael Compton, Payam Barnaghi, Luis Bermudez, Raul Garcia-Castro, Oscar Corcho, Simon Cox, John Graybeal, Manfred Hauswirth, Cory Henson, Arthur Herzog, Vincent Huang, Krzysztof Janowicz, W. David Kelsey, Danh Le Phuoc, Laurent Lefort, Myriam Leggieri, Holger Neuhaus, Andriy Nikolov, Kevin Page, Alexandre Passant, Amit Sheth, Kerry Taylor (2012), "The SSN Ontology of the W3C Semantic Sensor Network Incubator Group", J. Web Semantics, 17 (2012) [http

  3. Enzymatic synthesis of tRNA-peptide conjugates and spectroscopic studies of fluorine-modified RNA

    International Nuclear Information System (INIS)

    Graber, D.

    2010-01-01

    The research presented in this thesis concerns the enzymatic synthesis of artificially modified tRNA, in particular the preparation of non-hydrolysable tRNA-peptide conjugates. Another focus is on NMR-spectroscopic investigations of fluorine-modified RNA. In both projects, chemical methods were developed to address specific RNA-biological research questions. In the first part of this thesis the preparation of tRNA-peptide conjugates with a non-hydrolysable 3'-amide linkage is presented. These molecules are of high relevance for the characterization of ribosomal processes that occur in the peptidyl transferase center (such as peptide bond formation, peptide release, or translocation) using X-ray crystallography and biochemical methods. First, a novel concept to prepare chemically modified ('labeled') tRNA was elaborated based on the combination of solid-phase synthesis and enzymatic ligation. Thereby, a variety of differently labeled tRNAs was achieved. Moreover, the most successful high-yield ligation sites were identified to be situated within the TΨ C-loop. Optimization of the synthesis and the corresponding HPLC-purification of the conjugates were initially conducted with puromycin derivatized tRNA. In the course of this project, also two tRNAs with a ribose 3'-amino group at the terminal adenosine A76 were synthesized. For that purpose a protection group pattern had to be developed to obtain a functionalized solid-support bound to 3'-amino-3'-deoxyadenosine which was appropriate for RNA solid-phase synthesis. The successful preparation of tRNA-peptide conjugates was accomplished in cooperation with Holger Moroder and Jessica Steger (Micura group) who contributed short synthetic RNA-peptide conjugates. These fragments represented the tRNA 3'-termini that were required for exploring the new ligation strategies for non-hydrolisable tRNA - a main aim of this thesis. If the 5'-fragments are synthesized by solid-phase synthesis or in vitro transcription they do not

  4. Helmholtz international Summer school quantum field theory at the limits. From strong fields to heavy quarks (HQ 2016). Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Ali, Ahmed; Blaschke, David; Issadykov, Aidos; Ivanov, Mikhail (eds.)

    2017-04-15

    The Helmholtz International Summer School (HISS) entitled ''Quantum Field Theory at the Limits: from Strong Fields to Heavy Quarks (SF→HQ)'', was held in the period July 18-30, 2016 at the Bogolyubov Laboratory of Theoretical Physics (BLTP) of the Joint Institute for Nuclear Research (JINR) in Dubna, Russia, as part of the activities of the Dubna International Advanced School of Theoretical Physics (DIAS-TH). It was co-organized by Ahmed Ali (DESY Hamburg), David Blaschke (JINR Dubna, MEPhI and Univ. Wroclaw), Holger Gies (HI Jena), and Mikhail Ivanov (JINR Dubna), and was attended by 82 participants (faculty+students), not counting the JINR physicists who attended some lectures as non-registered participants. The school (SF→HQ) continued the workshops and schools of the HISS series held earlier in Dubna (1993, 1996, 2000, 2005, 2008, 2013), Bad Honnef (1994) and Rostock (1997). The scientific program of the school consisted of five regular (one-hour long) lectures in the morning and afternoon sessions, with typically two contributed talks given by younger participants (students and postdocs), each half-hour long, in the late afternoons. Altogether, we had sixty lectures by the faculty and participants. In addition, black-board exercises were held in the post-lunch periods on selected aspects of strong fields and field theory. The HISS series of schools has played an important role in bringing together an international faculty and young physicists (Ph.D. and postdocs), mostly from Russia and Germany, but increasingly also from other countries, including those affiliated to JINR Dubna. They participate in two-week long intense scientific discourse, mainly dedicated lectures on selected topics covering the foundation and the frontiers of high energy physics and cosmology. The novelty of this year's school was its bifocal interest, which brought together two different physical science communities - particle and laser physicists. There were

  5. Helmholtz international Summer school quantum field theory at the limits. From strong fields to heavy quarks (HQ 2016). Proceedings

    International Nuclear Information System (INIS)

    Ali, Ahmed; Blaschke, David; Issadykov, Aidos; Ivanov, Mikhail

    2017-04-01

    The Helmholtz International Summer School (HISS) entitled ''Quantum Field Theory at the Limits: from Strong Fields to Heavy Quarks (SF→HQ)'', was held in the period July 18-30, 2016 at the Bogolyubov Laboratory of Theoretical Physics (BLTP) of the Joint Institute for Nuclear Research (JINR) in Dubna, Russia, as part of the activities of the Dubna International Advanced School of Theoretical Physics (DIAS-TH). It was co-organized by Ahmed Ali (DESY Hamburg), David Blaschke (JINR Dubna, MEPhI and Univ. Wroclaw), Holger Gies (HI Jena), and Mikhail Ivanov (JINR Dubna), and was attended by 82 participants (faculty+students), not counting the JINR physicists who attended some lectures as non-registered participants. The school (SF→HQ) continued the workshops and schools of the HISS series held earlier in Dubna (1993, 1996, 2000, 2005, 2008, 2013), Bad Honnef (1994) and Rostock (1997). The scientific program of the school consisted of five regular (one-hour long) lectures in the morning and afternoon sessions, with typically two contributed talks given by younger participants (students and postdocs), each half-hour long, in the late afternoons. Altogether, we had sixty lectures by the faculty and participants. In addition, black-board exercises were held in the post-lunch periods on selected aspects of strong fields and field theory. The HISS series of schools has played an important role in bringing together an international faculty and young physicists (Ph.D. and postdocs), mostly from Russia and Germany, but increasingly also from other countries, including those affiliated to JINR Dubna. They participate in two-week long intense scientific discourse, mainly dedicated lectures on selected topics covering the foundation and the frontiers of high energy physics and cosmology. The novelty of this year's school was its bifocal interest, which brought together two different physical science communities - particle and laser physicists. There were

  6. PREFACE: The Eighth Liquid Matter Conference The Eighth Liquid Matter Conference

    Science.gov (United States)

    Dellago, Christoph; Kahl, Gerhard; Likos, Christos N.

    2012-07-01

    The Eighth Liquid Matter Conference (LMC8) was held at the Universität Wien from 6-10 September 2011. Initiated in 1990, the conferences of this series cover a broad range of highly interdisciplinary topics, ranging from simple liquids to soft matter and biophysical systems. The vast spectrum of scientific subjects presented and discussed at the LMC8 is reflected in the themes of the ten symposia: Ionic and quantum liquids, liquid metals Water, solutions and reaction dynamics Liquid crystals Polymers, polyelectrolytes, biopolymers Colloids Films, foams, surfactants, emulsions, aerosols Confined fluids, interfacial phenomena Supercooled liquids, glasses, gels Non-equilibrium systems, rheology, nanofluids Biofluids, active matter This special issue contains scientific papers, authored by participants of the LMC8, which provide a cross-section of the scientific activities in current liquid matter science, as discussed at the conference, and demonstrate the scientific as well as methodological progress made in this field over the past couple of years. The Eighth Liquid Matter Conference contents The Eighth Liquid Matter ConferenceChristoph Dellago, Gerhard Kahl and Christos N Likos Comparing light-induced colloidal quasicrystals with different rotational symmetriesMichael Schmiedeberg and Holger Stark Hydrogen bond network relaxation in aqueous polyelectrolyte solutions: the effect of temperatureS Sarti, D Truzzolillo and F Bordi Equilibrium concentration profiles and sedimentation kinetics of colloidal gels under gravitational stressS Buzzaccaro, E Secchi, G Brambilla, R Piazza and L Cipelletti The capillary interaction between two vertical cylindersHimantha Cooray, Pietro Cicuta and Dominic Vella Hydrodynamic and viscoelastic effects in polymer diffusionJ Farago, H Meyer, J Baschnagel and A N Semenov A density-functional theory study of microphase formation in binary Gaussian mixturesM Carta, D Pini, A Parola and L Reatto Microcanonical determination of the

  7. Energy from waste. Vol. 2; Energie aus Abfall. Bd. 2

    Energy Technology Data Exchange (ETDEWEB)

    Thome-Kozmiensky, K.J.; Beckmann, M.

    2007-07-01

    treatment plants with grate firing (Michael Mueck, Werner Hansen, Hans-Peter Alessio); (b) BWV-combustion technology for energy production from waste - a case study: Reno North, line 4. Waste incineration plant with a high effiency (Hans Boegh Andersen); (c) Determination of operational parameters in waste incinerators as a prerequisite for further optimisation (Martin Horeni, Michael Beckmann, Hans Fleischmann, Erhard Barth); (d) Optimization of thermal waste treatment with the INSPECT system by camera based characteristic values and Fuzzy Control (Hubert B. Keller, Joerg Matthes, Holger Schoeenecker, Tristan Krakau); (e) Renewal of process control systems in the waste incineration plant Ruhleben (Thomas Kempin, Henrik Zahn); (f) Fuzzy Control in the waste incineration plant of BSR under consideration of process optimization and economy (Thomas Kempin, Peter Knoop, Henrik Zahn, Christian Gierend). The next chapter 'New plants and extension of plants' contains the following plants: (a) New construction of a waste incinerator in Delfzijl/NL (Matthias Elfers); (b) Replace of waste incinerators at existing sites (Gert Riemenschnieder, Walter Schaefer); (c) Modernisation of the waste-fired cogeneration plant Frankfurt (Gerhard Lohe); (d) Design of plants, supply of fuels and quality control for waste incinerators (Reinhard Schu, Jens Niestroj); (e) Utilization of a water-cooled cooking grate - concept and operating experiences (Werner Auel, Manfred Kuehl); (f) The forward moving combustion grate from Jakob Stiefel GmbH - concept, plants and experiences (Martin Stiefel). The following chapter 'Exhaust gas purification' consists of the following chapters: (a) Does there exist a problem of fine dust or mercury at the waste incineration? (Heidi Foth); (b) Trends in the exhaust gas purification according to the control of the problem of fine dust or mercury - technical solutions (Christoph Mueller, Reiner Stark); (c) Measures and experiments to the reduction of

  8. On the dynamics of excited atoms in time dependent electromagnetic fields

    International Nuclear Information System (INIS)

    Foerre, Morten

    2004-06-01

    This thesis is composed of seven scientific publications written in the period 2001-2004. The focus has been set on Rydberg atoms of hydrogen and lithium in relatively weak electromagnetic fields. Such atoms have been studied extensively during many years, both experimentally and theoretically, They are relatively easy to handle in the laboratory. Their willingness to react to conventional field sources and their long lifetimes, are two reasons for this. Much new insight into fundamental quantum mechanics has been extracted from such studies. By exciting a non-hydrogenic ground state atom or molecule into a highly excited state, many properties of atomic hydrogen are adopted. In many cases the dynamics of such systems can be accurately described by the hydrogenic theory, or alternatively by some slightly modified version like quantum defect theory. In such theories the Rydberg electron(s) of the non-hydrogenic Rydberg system is treated like it is confined in a modified Coulomb potential, which arises from the non-hydrogenic core. defined by the non-excited electrons and the nucleus. The more heavily bound core electrons are less influenced from external perturbations than the excited electrons, giving rise to the so-called frozen-core approximation. where the total effect of the core electrons is put into a modified Coulomb potential. A major part of this thesis has been allocated to the study of core effects in highly excited states of lithium. In collaboration with time experimental group of Erik Horsdal-Pedersen at Aarhus University, we have considered several hydrogenic and non-hydrogenic aspects of such states, when exposed to weak slowly varying electromagnetic fields. The dynamics was restricted to one principal shell (intrashell). Two general features were observed, either the hydrogenic theory applied or alternatively, in case of massive deviation, the dynamics was accurately described by quantum defect theory, clearly demonstrating the usefulness of such

  9. Comparison of publically available Moho depth and crustal thickness grids with newly derived grids by 3D gravity inversion for the High Arctic region.

    Science.gov (United States)

    Lebedeva-Ivanova, Nina; Gaina, Carmen; Minakov, Alexander; Kashubin, Sergey

    2016-04-01

    deep Arctic Ocean: results of a 3D gravity modeling Russian Geology and Geophysics 54, 247-262. Jakobsson M, Mayer L, Coakley B, Dowdeswell JA, Forbes S, Fridman B, Hodnesdal H, Noormets R, Pedersen R, Rebesco M, Schenke HW, Zarayskaya Y, Accettella D, Armstrong A, Anderson RM, Bienhoff P, Camerlenghi A, Church I, Edwards M, Gardner JV, Hall JK, Hell B, Hestvik O, Krist-offersen Y, Marcussen C, Mohammad R, Mosher D, Nghiem SV, Pedrosa MT, Travaglini PG, Weatherall P (2012). The international bathymetric chart of the Arctic Ocean (IBCAO) version 3.0. Geophys Res Lett 39, L12609. Laske, G., Masters., G., Ma, Z. and Pasyanos, M. (2013). Update on CRUST1.0 - A 1-degree Global Model of Earth's Crust, Geophys. Res. Abstracts, 15, Abstract EGU2013-2658, 2013. Minakov A, Faleide JI, Glebovsky VY, Mjelde R (2012) Structure and evolution of the northern Barents-Kara Sea continental margin from integrated analysis of potential fields, bathymetry and sparse seismic data. Geophys J Int 188, 79-102. Petrov O., Smelror M., Shokalsky S., Morozov A., Kashubin S., Grikurov G., Sobolev N., Petrov E., (2013). A new international tectonic map of the Arctic (TeMAr) at 1:5 M scale and geodynamic evolution in the Arctic region. EGU2013-13481. Reguzzoni, M., & Sampietro, D. (2014). GEMMA: An Earth crustal model based on GOCE satellite data. International Journal of Applied Earth Observation and Geoinformation Spasojevic S. & Gurnis M., (2012). Sea level and vertical motion of continents from dynamic earth models since the late Cretaceous. American Association of Petroleum Geologists Bulletin, 96, pp. 2037-2064.

  10. Microbiology, Redox and Contaminat Fate in the Grindsted Landfill Leachate Plume - A Summary of 25 Years of work

    Science.gov (United States)

    Christensen, T. H.

    2001-05-01

    experiments. Ground Water, 37, 113-121. Bjerg, P.L., Rugge, K., Pedersen, J.K. & Christensen, T.H. (1995): Distribution of redox sensitive groundwater quality parameters downgradient of a landfill (Grindsted, Denmark). Environmental Science and Technology, 29, 1387-1394. Heron, G., Bjerg, P.L., Gravesen, P., Ludvigsen, L. & Christensen, T.H. (1998): Geology and sediment geochemistry of a landfill leachate contaminated aquifer (Grindsted, Denmark). Journal of Contaminant Hydrology, 29, 301-317. Jakobsen, R., Albrechtsen, H.-J., Rasmussen, M., Bay, H., Bjerg, P.L. & Christensen, T.H. (1998): H2 concentrations in a landfill leachate plume (Grindsted, Denmark): In situ energetics of terminal electron acceptor processes. Environmental Science and Technology, 32, 2142-2148. Ludvigsen, L., Albrechtsen, H.-J., Heron, G., Bjerg, P.L. & Christensen, T.H. (1998): Anaerobic microbial redox processes in a landfill leachate contaminated aquifer (Grindsted, Denmark). Journal of Contaminant Hydrology, 33, 273-291. Ludvigsen, L., Albrechtsen, H.-J., Ringelberg, D., Ekelund, F. & Christensen, T.H. (1999): Distribution and composition of microbial populations in a landfill leachate contaminated aquifer (Grindsted, Denmark). Microbial Ecology, 37, (3), 197-207. Rugge, K., Bjerg, P.L. & Christensen, T.H. (1995): Distribution of organic compounds from municipal solid waste in the groundwater downgradient of a landfill (Grindsted, Denmark). Environmental Science and Technology, 29, 1395-1400.

  11. Shallow conduit processes of the 1991 Hekla eruption, Iceland

    Science.gov (United States)

    Gudnason, J.; Thordarson, T.; Houghton, B. F.

    2013-12-01

    ., et al., The 1991 eruption of Hekla, Iceland. Bulletin of Volcanology, 1992. 54(3): p. 238-246. 2. Höskuldsson, Á., Óskarsson, N., Pedersen, R., Grönvold, K., Vogfjörd, K. & Ólafsdóttir, R. 2007. The millennium eruption of Hekla in February 2000. Bull Volcanol, 70:169-182. 3. Larsen, G., E.G. Vilmundardóttir, and B. Thorkelsson, Heklugosid 1991: Gjóskufall og gjóskulagid frá fyrsta degi gossins. Náttúrufrædingurinn, 1992. 61(3-4): p. 159-176.

  12. Simulation with models of increasing complexity of CO2 emissions and nitrogen mineralisation, after soil application of labelled pig slurry and maize stalks

    Science.gov (United States)

    Bechini, Luca; Marino Gallina, Pietro; Geromel, Gabriele; Corti, Martina; Cavalli, Daniele

    2015-04-01

    ST15 mineralisation until day 7. Due to model structure, trade-offs exist between a good simulation of CO2 emissions and a good simulation of SMN. Therefore, simulation performances of the three models are a compromise between the errors in the simulation of C and N dynamics. Thus, some models (especially the simplest one), overestimated or underestimated SMN to match CO2 measurements. This preliminary work emphasised the importance of testing models with both C and N measurements. This reduced the risk of obtaining model parameters suitable for the simulation of N (or opposite C) dynamics that lead to unrealistic simulation of C (or N) decomposition. The use of 15N-labelled materials will help to improve models for the simulation of added organic matter decomposition. Kätterer, T., Andrén, O., 2001. The ICBM family of analytically solved models of soil carbon, nitrogen and microbial biomass dynamics'descriptions and application examples. Ecol. Model. 136, 191-207. doi:10.1016/S0304-3800(00)00420-8. Petersen, B.M., Jensen, L.S., Hansen, S., Pedersen, A., Henriksen, T.M., Sørensen, P., Trinsoutrot-Gattin, I., Berntsen, J., 2005. CN-SIM: a model for the turnover of soil organic matter. II. Short-term carbon and nitrogen development. Soil Biol. Biochem. 37, 375-393. doi:10.1016/j.soilbio.2004.08.007.

  13. Relation between magnetic fields and electric currents in plasmas

    Directory of Open Access Journals (Sweden)

    V. M. Vasyliunas

    2005-10-01

    ∇×E, with E determined by plasma dynamics via the generalized Ohm's law; as illustrative simple examples, I discuss the formation of magnetic drift currents in the magnetosphere and of Pedersen and Hall currents in the ionosphere.

    Keywords. Ionosphere (Electric fields and currents – Magnetospheric physics (Magnetosphere-ionosphere interactions – Space plasma physics (Kinetic and MHD theory

  14. On the dynamics of excited atoms in time dependent electromagnetic fields

    Energy Technology Data Exchange (ETDEWEB)

    Foerre, Morten

    2004-06-01

    This thesis is composed of seven scientific publications written in the period 2001-2004. The focus has been set on Rydberg atoms of hydrogen and lithium in relatively weak electromagnetic fields. Such atoms have been studied extensively during many years, both experimentally and theoretically, They are relatively easy to handle in the laboratory. Their willingness to react to conventional field sources and their long lifetimes, are two reasons for this. Much new insight into fundamental quantum mechanics has been extracted from such studies. By exciting a non-hydrogenic ground state atom or molecule into a highly excited state, many properties of atomic hydrogen are adopted. In many cases the dynamics of such systems can be accurately described by the hydrogenic theory, or alternatively by some slightly modified version like quantum defect theory. In such theories the Rydberg electron(s) of the non-hydrogenic Rydberg system is treated like it is confined in a modified Coulomb potential, which arises from the non-hydrogenic core. defined by the non-excited electrons and the nucleus. The more heavily bound core electrons are less influenced from external perturbations than the excited electrons, giving rise to the so-called frozen-core approximation. where the total effect of the core electrons is put into a modified Coulomb potential. A major part of this thesis has been allocated to the study of core effects in highly excited states of lithium. In collaboration with time experimental group of Erik Horsdal-Pedersen at Aarhus University, we have considered several hydrogenic and non-hydrogenic aspects of such states, when exposed to weak slowly varying electromagnetic fields. The dynamics was restricted to one principal shell (intrashell). Two general features were observed, either the hydrogenic theory applied or alternatively, in case of massive deviation, the dynamics was accurately described by quantum defect theory, clearly demonstrating the usefulness of such

  15. Pulmonary Function Affects Language Performance in Aging

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    Lewina O Lee

    2014-04-01

    Full Text Available Background Good pulmonary function (PF is associated with preservation of cognitive performance, primarily of executive functions, in aging (Albert et al., 1995; Chyou et al., 1996; Emery, Finkel, & Pedersen, 2012; Yohannes & Gindo, 2013. The contribution of PF to older adults’ language abilities, however, has never been explored, to our knowledge. We addressed this gap by examining the effects of PF on older adults’ language functions, as measured by naming and sentence processing accuracy. We predicted similar effects as found for executive functions, given the positive associations between executive functions and sentence processing in aging (e.g., Goral et al., 2011. Methods Data were collected from 190 healthy adults aged 55 to 84 years (M = 71.1, SD = 8.1, with no history of neurological or psychiatric disorders. Procedure PF was measured prior to language testing. Measures included forced expiratory volume in 1 second (FEV1 and forced vital capacity (FVC. Language functions were assessed through performance on computer-administered lexical retrieval and sentence processing tasks. Sentence processing was measured using two auditory comprehension tasks: one, of embedded sentences (ES, the other, of sentences with multiple negatives (MN. Lexical retrieval was measured using the Boston Naming Test (BNT and Action Naming Test (ANT. Performance was scored for percent accuracy. Additionally, lexical retrieval was evaluated with a phonemic fluency task (FAS, which also taps executive function abilities. Statistical Analyses Multiple regression was used to examine the association between pulmonary and language functions, adjusting for age, education, gender, history of respiratory illness, current level of physical activities, and current and past smoking. Results Better PF was associated with better sentence processing and lexical retrieval on naming tasks, but not with phonemic fluency, after adjusting for covariates. Higher FVC was

  16. Cohort description: The Danish study of Functional Disorders

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    Dantoft TM

    2017-02-01

    Full Text Available Thomas Meinertz Dantoft,1 Jeanette Frost Ebstrup,1 Allan Linneberg,1–3 Sine Skovbjerg,1 Anja Lykke Madsen,1 Jesper Mehlsen,4 Louise Brinth,4 Lene Falgaard Eplov,5 Tina Wisbech Carstensen,6,7 Andreas Schroder,6,7 Per Klausen Fink,6,7 Erik Lykke Mortensen,8 Torben Hansen,9 Oluf Pedersen,9 Torben Jørgensen1,10,11 1Research Centre for Prevention and Health, The Capital Region of Denmark, Glostrup, 2Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 3Department of Clinical Experimental Research, Rigshospitalet, Glostrup, 4Coordinating Research Centre, Bispebjerg and Frederiksberg Hospital, Frederiksberg, 5Mental Health Centre Copenhagen, Research Unit, Mental Health Services, Capital Region of Denmark, Copenhagen, 6The Research Clinic for Functional Disorders and Psychosomatics, Aarhus University Hospital, 7Faculty of Health Sciences, University of Aarhus, Aarhus, 8Department of Public Health and Center for Healthy Aging, 9Novo Nordisk Foundation Center for Basic Metabolic Research, 10Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, 11Faculty of Medicine, Aalborg University, Aalborg, Denmark Abstract: The Danish study of Functional Disorders (DanFunD cohort was initiated to outline the epidemiology of functional somatic syndromes (FSS and is the first larger coordinated epidemiological study focusing exclusively on FSS. FSS are prevalent in all medical settings and can be defined as syndromes that, after appropriate medical assessment, cannot be explained in terms of a conventional medical or surgical disease. FSS are frequent and the clinical importance varies from vague symptoms to extreme disability. No well-described medical explanations exist for FSS, and how to delimit FSS remains a controversial topic. The specific aims with the cohort were to test delimitations of FSS, estimate prevalence and incidence rates, identify risk factors

  17. Mineralogy and Acid-Extractable Geochemistry from the Loki's Castle Hydrothermal Field, Norwegian Sea at 74 degrees N (South Knipovich Ridge)

    Science.gov (United States)

    Barriga, F. J.; Fonseca, R.; Dias, S.; Cruz, I.; Carvalho, C.; Relvas, J. M.; Pedersen, R.

    2010-12-01

    The Loki’s Castle hydrothermal vent field was discovered in the summer of 2008 during a cruise led by the Centre of Geobiology of the University of Bergen, integrated in the H2Deep Project (Eurocores, ESF; see Pedersen et al., 2010, AGU Fall Meeting, Session OS26). Fresh volcanic glasses analyzed by EPMA are basalts. The vent site is composed of several active, over 10 m tall chimneys, producing up to 320 C fluid, at the top of a very large sulfide mound (estimated diameter 200 m). Mineralogy: The main sulfide assemblage in chimneys consists of sphalerite (Sp), pyrite (Py) and pyrrhotite, with lesser chalcopyrite (Ccp). Sulphide-poor selected samples collected at the base of chimneys are mostly composed of anhydrite (Anh), gypsum and talc (Tlc). Association of quartz, anhydrite, gypsum and barite were also found in some of the samples. The sulphide-poor samples from the base of the chimneys denote seawater interaction with the hydrothermal fluid and consequent decrease in temperature, precipitating sulfates. Sphalerite compositions are Zn(0.61-0.70)Fe(0.39-0.30)S. The variations in Fe content are consistent with those of hot, reduced hydrothermal fluids. The observed sulfide assemblage is consistent with the temperature of 320C measured in Loki’s Castle vents. Compositional zonation in sphalerites suggests different pulses of activity of the hydrothermal system, with higher contents of Zn in the center of the crystals. Geochemistry: Here we report preliminary data part of a major analytical task of sequential extraction of metals from sediments in the vicinity of Loki’s Castle, in an attempt to detect correlations with microbial populations and/or subseafloor mineralized intervals. The abundances of Cu, Pb, Ni, Cr, Zn, Fe, Mn and Co in sediments were determined by aqua regia extraction on subsamples from 7 gravity cores. Several anomalous intervals were sampled, in which Cu<707ppm, Ni shows many weak peaks (<50ppm), Cr shows 6 peaks (<121ppm), Zn shows 4 well

  18. Moving towards persistent identification in the seismological community

    Science.gov (United States)

    Quinteros, Javier; Evans, Peter; Strollo, Angelo; Ulbricht, Damian; Elger, Kirsten; Bertelmann, Roland

    2016-04-01

    centre. These will be used for replication and versioning of the data. This will support reproducible, fine-grained citation of seismic waveform data in a consistent fashion. Moreover, we plan to create also PIDs for collections of PIDs, in order to support the citation of a set of many data files with a single identifier. The technical information describing the instruments used to acquire the data and their location will most probably be also identified with a PID (to a StationXML record) and pointed to from the metadata of the waveform PID. StationXML will also include the DOI of the network for citation purposes. With all these elements, progress towards reproducibility and better attribution are gained. References - EIDA (2016): European Integrated Data Archive (EIDA) . http://www.orfeus-eu.org/eida/eida.html - Evans, P., Strollo, A., Clark, A., Ahern, T., Newman, R., Clinton, J. F., Pedersen, H., Pequegnat, C. (2015 online): Why Seismic Networks Need Digital Object Identifiers. - Eos, Transactions American Geophysical Union, 96. http://doi.org/10.1029/2015EO036971 - International Federation of Digital Seismograph Networks (FDSN) (2013): FDSN Web Service Specifications, Version 1.1b, 2013/10/25. http://www.fdsn.org/webservices/FDSN-WS-Specifications-1.1.pdf - International Federation of Digital Seismograph Networks (FDSN) (2014), FDSN recommendations for seismic network DOIs and related FDSN services [WG3 recommendation], http://doi.org/10.7914/D11596.

  19. Intervensjonsstudien "Forebyggelse av lårhalsbrudd". Metode og praktisk gjennomføring

    Directory of Open Access Journals (Sweden)

    Elisabeth Kvaavik

    2009-11-01

    -blinded, controlled trial in nursing homes. The intervention group received10 : Vitamin D deficiency is a potential important risk factor for osteoporotic fractures. We havecarried out a trial in nursing homes residents to study if supplementation with vitamin D ENGLISH SUMMARY: Deltakelsen var lavere enn forventet idet det var betydelige vansker med å rekruttere sykehjemsbeboeretil studien, men de avdelinger som deltok fant gjennomføringen av studien lite arbeidskrevende.Totalt ble 1144 inkludert i studien.Kvaavik E, Meyer HE, Smedshaug GB, Falch JA, Tverdal A, Pedersen JI. : I alt 1144 beboere ved 51 sykehjem (av 106 forespurte i Oslo, Lier og Bergen deltok. Deltakelsenved de enkelte sykehjem varierte fra 3 til 57% av beboerne. Deltakerne var i gjennomsnitt 85 år og3/4 var kvinner. Kalsiuminntak fra ost og melk var i gjennomsnitt 450 mg/dag, 40% brukte vitamin Dtilskudddaglig mens 3% brukte kalsiumtilskudd. 1/3 av deltakerne fullførte intervensjonen, ca. 1/3 avsluttetfør 2 år pga. død og 1/3 avsluttet før 2 år av andre årsaker. De fleste avdelingslederne fant det litearbeidskrevende å gjennomføre intervensjonen.: En randomisert, dobbelt blindet, kontrollert studie på sykehjem. Intervensjonsgruppa fikk i 2 år10 : Vitamin D-mangel er en potensielt viktig risikofaktor for osteoporotiske brudd. Vi har gjennomførten studie for å teste om vitamin D SAMMENDRAG

  20. Inflammation-modulating cytokine profile and lipid interaction in HIV-related risk factors for cardiovascular diseases

    Directory of Open Access Journals (Sweden)

    Gori E

    2016-11-01

    Full Text Available Elizabeth Gori,1,2 Takafira Mduluza,3,4 Mudavanhu Nyagura,2 Babill Stray-Pedersen,5 Zvenyika Alfred Gomo1 1Chemical Pathology Department, College of Health Sciences, 2Preclinical Veterinary Studies Department, Faculty of Veterinary Sciences, 3Biochemistry Department, University of Zimbabwe, Harare, Zimbabwe; 4School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa; 5Institute of Clinical Medicine, University in Oslo, Oslo University Hospital, Oslo, Norway Abstract: HIV infection and antiretroviral therapy (ART are associated with changes in plasma levels of lipoproteins, thus posing the risk of cardiovascular complications in infected individuals. The alteration in plasma lipoprotein levels results from dysregulation of inflammation-modulating cytokines that control lipid metabolism. Little is understood regarding the relationship between the cytokines and serum lipid levels, which have been reported to be altered in adults receiving ART. The objective of this study was to describe the profiles of inflammation-modulating cytokines and their relationship to lipids as cardiovascular disease (CVD risk factors in HIV infection. This observational cross-sectional study measured plasma levels of interleukin (IL-10, tumor necrosis factor-alpha (TNF-α, IL-4, total cholesterol (TC, and high-density lipoprotein cholesterol (HDL-c in HIV-infected and uninfected adults. A total of 219 HIV-infected participants were enrolled from an HIV treatment center; of them, 187 were receiving ART and 32 were ART naïve, while 65 were HIV-uninfected blood donors. HIV-infected individuals had higher levels of IL-10 (HIV-infected ART-naïve [P=0.0024] and ART-receiving [P=0.033] than their uninfected counterparts. ART-naïve subjects had significantly higher plasma levels of IL-10 than ART-receiving subjects (P=0.0014. No significant difference was observed in plasma levels of IL-4 and TNF

  1. Generation of mesoscale F layer structure and electric fields by the combined Perkins and Es layer instabilities, in simulations

    Directory of Open Access Journals (Sweden)

    R. B. Cosgrove

    2007-07-01

    Full Text Available The generic equilibrium configuration of the nighttime midlatitude ionosphere consists of an F layer held up against gravity by winds and/or electric fields, and a sporadic E (Es layer located by a sheared wind field, which experiences the same electric fields as the F layer. This configuration is subject to two large-scale (e.g. >10 km "layer instabilities": one of the F layer known as the Perkins instability, and another of the Es layer which has been called the Es layer instability. Electric fields on scales larger than (about 10 km map very efficiently between the Es and F layers, and the two instabilities have a similar geometry, allowing them to interact with one another. As shown through a linear growth rate analysis, the two most important parameters governing the interaction are the relative horizontal velocity between the Es and F layers, and the integrated conductivity ratio ΣH/ΣPF, where ΣH and ΣPF are the field line integrated Hall conductivity of the Es layer, and the field line integrated Pedersen conductivity of the F layer, respectively. For both large and small relative velocities the growth rate was found to be more than double that of the Perkins instability alone, when ΣHΣPF=1.8. However, the characteristic eigenmode varies considerably with relative velocity, and different nonlinear behavior is expected in these two cases. As a follow up to the linear growth rate analysis, we explore in this article the nonlinear evolution of the unstable coupled system subject to a 200 km wavelength initial perturbation of the F layer, using a two-dimensional numerical solution of the two-fluid equations, as a function of relative horizontal velocity and ΣHΣPF. We find that when ΣHΣPF⪝0.5 the Perkins instability is able to control the dynamics and modulate the F layer altitude in 2 to 3 h time. However, the electric fields remain small until the altitude modulation is extremely large, and even then they are not large enough to

  2. Control of moderate-to-severe asthma with randomized ciclesonide doses of 160, 320 and 640 μg/day

    Directory of Open Access Journals (Sweden)

    Pedersen SE

    2017-03-01

    Full Text Available Søren E Pedersen,1 Niyati Prasad,2 Udo-Michael Goehring,3 Henrik Andersson,4 Dirkje S Postma5 1Pediatric Research Unit, Kolding Hospital, University of Southern Denmark, Kolding, Denmark; 2Vertex, Phase IV & Global Strategy, London, UK; 3Vifor Pharma Ltd, Clinical Research & Biometrics, Glattbrugg, Switzerland; 4Swedish Social Insurance Agency, Government Offices of Sweden, Stockholm, Sweden; 5Department of Pulmonology, Griac Research Institute, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands Background: The inhaled corticosteroid (ICS ciclesonide (Cic, controls asthma symptoms in the majority of patients at the recommended dose of 160 µg/day. However, the relationship between the level of asthma control and increasing doses of Cic is unknown. This study investigated whether long-term treatment with higher doses of Cic would further improve asthma symptoms in patients with uncontrolled asthma despite ICS use. Patients and methods: In a double-blind, randomized, parallel-group study, 367 patients were allocated to one of three treatment arms (Cic 160, 320 and 640 μg/day. After a single-blind, 3-week baseline period with Cic 160 µg/day, eligible patients were randomized to receive 52 weeks of treatment with Cic 160, 320 or 640 μg/day (double-blind period during which forced expiratory volume in 1 second (FEV1, exacerbations and Asthma Control Questionnaire (ACQ scores were measured. Results: Treatment with all the three doses was associated with significant improvements in ACQ scores, FEV1 and asthma symptoms (P<0.01. There were no statistically significant differences between the three doses. The results of the primary end point analysis showed a numerical improvement in the ACQ score with Cic 640 μg/day compared with Cic 160 μg/day (least square [LS] mean: -0.122; two-sided P-value: 0.30. Post hoc subgroup analyses showed that the improvement in the ACQ score with Cic 640 μg/day compared

  3. Vejle Diabetes Biobank – a resource for studies of the etiologies of diabetes and its comorbidities

    Directory of Open Access Journals (Sweden)

    Petersen ERB

    2016-10-01

    Full Text Available Eva Rabing Brix Petersen,1,2 Aneta Aleksandra Nielsen,1 Henry Christensen,1 Torben Hansen,3 Oluf Pedersen,3 Cramer Kjeldahl Christensen,4 Ivan Brandslund1,2 1Department of Clinical Immunology and Biochemistry, Lillebaelt Hospital, Vejle, 2Faculty of Health Sciences, Institute of Regional Health Research, University of Southern Denmark, Odense, 3Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 4Department of Internal Medicine and Endocrinology, Lillebaelt Hospital, Vejle, Denmark Aims: Carefully designed and established biobanks are considered one of the most essential resources to foster biomedical research as they provide cost-effective and rapid access to a vast variety of biological materials and related anthropometrics allowing for testing of various biomarkers as well as numerous original and pertinent bioclinical hypotheses related to human disease etiology and prognosis. The objective of the present study was to present the baseline data, design, and methods used for the establishment of the Vejle Diabetes Biobank. Further aims included assessment of the prevalence of diabetes and quality of diabetes treatment in a specified Danish region.Methods: The Vejle Diabetes Biobank was established from 2007 to 2010 as a regional Biobank containing blood, DNA, and urine samples from patients with diabetes and a gender- and age-matched control population aged 25–75 years. Anthropometrics were obtained by physical examination, questionnaires, and interviews at the time of inclusion into the Biobank. The cohort was linked to the Danish Civil Registration System, the Danish National Patient Registry, and the Danish National Prescription Registry.Results: In total, 4,255 nondiabetic individuals and 3,320 patients with diabetes were included. Type 2 diabetes (T2D patients had a higher body mass index (30 kg/m2 than type 1 diabetes

  4. Auroral Substorms: Search for Processes Causing the Expansion Phase in Terms of the Electric Current Approach

    Science.gov (United States)

    Akasofu, Syun-Ichi

    2017-10-01

    Pedersen and Hall currents and thus generates the UL current system. (5) A significant part of the magnetic energy is accumulated in the main body of the magnetosphere (the inner plasma sheet) between 4 Re and 10 Re, because the power (Poynting flux [ E × B ]) is mainly directed toward this region which can hold the substorm energy. (6) The substorm intensity depends on the location of the energy accumulation (between 4 Re and 10 Re), the closer the location to the earth, the more intense substorms becomes, because the capacity of holding the energy is higher at closer distances. The convective flow toward the earth brings both the ring current and the plasma sheet current closer when the dynamo power becomes higher. This proposed sequence is not necessarily new. Individual processes involved have been considered by many, but the electric current approach can bring them together systematically and provide some new quantitative insights.

  5. BREATHING 100% O2 HAS NO EFFECT ON BLOOD LACTATE CONCENTRATION DURING A SHORT PASSIVE RECOVERY FROM EXHAUSTIVE EXERCISE

    Directory of Open Access Journals (Sweden)

    Bartholomew Kay

    2005-06-01

    Full Text Available Many researchers (e.g. Coffey et al., 2004 have indicated that recovery from acute exercise induced muscular fatigue could be expedited by increased rapidity of lactate (LA- clearance from the blood. This argument is based on the following logical progression: Firstly, increased intra-myocellular LA- concentration has been proposed to exert various deleterious electrochemical influences over excitation/contraction coupling and metabolic function (e.g. Favero et al., 1997. Secondly, because LA- is extruded from the muscle cells to the blood in a concentration gradient dependent fashion (Mengual et al., 2003; lowered blood LA- concentration should therefore allow increased rapidity of myocellular LA- export. Finally, LA- accumulation is continually cited as having a causal relationship with exercise induced acidosis; and further that such acidosis is deleterious to muscular function (for review see Pedersen et al., 2004. Given that protons are co-transported out of the muscle cells with LA- at a 1:1 ratio (Mengual et al., 2003; it may appear this is another reason for suggesting increased LA- extrusion rate could be beneficial. Several challenges to the above logic can be made: Firstly, the negative effects of increased LA- concentration alluded to above are absent at physiological pH and temperature in situ: at concentrations as high as 30 mMol·L-1 (for review, see Allen and Westerblad, 2001. Secondly, at higher intra-myocellular LA- concentrations, pyruvate is imported from the blood to rebalance redox and metabolic equilibria, including the ratio of NAD+:NADH + H+ (Mengual et al., 2003. This process therefore theoretically counteracts the proposed need to remove LA- from the blood in order to facilitate continued myocellular LA- efflux. Furthermore, LA- accumulation is not causally linked to acidification (Robergs et al., 2004, and there is evidence that acidification is beneficial to muscular function in any case (Pedersen et al., 2004

  6. The Dark Side of Nature: the Crime was Almost Perfect

    Science.gov (United States)

    2006-12-01

    Astrofisico di Arcetri, Italy), Guido Chincarini (INAF, Osservatorio Astronomico di Brera & Università degli Studi di Milano-Bicocca, Italy), Nino Panagia (Space Telescope Science Institute, USA), Gianpiero Tagliaferri, Dino Fugazza, Sergio Campana, Stefano Covino, and Paolo D'Avanzo (INAF, Osservatorio Astronomico di Brera, Italy), Daniele Malesani (SISSA/ISAS, Italy and Dark Cosmology Centre, Copenhagen), Vincenzo Testa, L. Angelo Antonelli, Silvia Piranomonte, and Luigi Stella (INAF, Osservatorio Astronomico di Roma, Italy), Vanessa Mangano (INAF/IASF Palermo, Italy), Kevin Hurley (University of California, Berkeley, USA), I. Felix Mirabel (ESO), and Leonardo J. Pellizza (Instituto de Astronomia y Fisica del Espacio). The Danish-led team is composed of Johan P. U. Fynbo, Darach Watson, Christina C. Thöne, Tamara M. Davis, Jens Hjorth, José Mará Castro Cerón, Brian L. Jensen, Maximilian D. Stritzinger, and Dong Xu (Dark Cosmology Centre, University of Copenhagen, Denmark), Jesper Sollerman (Dark Cosmology Centre and Department of Astronomy, Stockholm University, Sweden), Uffe G. Jørgensen, Tobias C. Hinse, and Kristian G. Woller (Niels Bohr Institute, University of Copenhagen), Joshua S. Bloom, Daniel Kocevski, Daniel Perley (Department of Astronomy, University of California at Berkeley, USA), Páll Jakobsson (Centre for Astrophysics Research, University of Hertfordshire, UK), John F. Graham and Andrew S. Fruchter (Space Telescope Science Institute, Baltimore, USA), David Bersier (Astrophysics Research Institute, Liverpool John Moores University, UK), Lisa Kewley (University of Hawaii, Institute of Astronomy, USA), Arnaud Cassan and Marta Zub (Astronomisches Rechen-Institut, Zentrum für Astronomie der Universität Heidelberg, Germany), Suzanne Foley (School of Physics, University College Dublin, Ireland), Javier Gorosabel (Instituto de Astrofisica de Andalucia, Granada, Spain), Keith D. Horne (SUPA Physics/Astronomy, University of St Andrews, Scotland, UK), Sylvio

  7. EDITORIAL: Colloidal dispersions in external fields Colloidal dispersions in external fields

    Science.gov (United States)

    Löwen, Hartmut

    2012-11-01

    ller, Bastian Sieber, Holger Schweinfurth, Holger Reiber and Gerhard Nägele Electrokinetics on superhydrophobic surfacesPeriklis Papadopoulos, Xu Deng, Doris Vollmer and Hans-Jürgen Butt Numerical electrokineticsR Schmitz and B Dünweg Dielectric response of nanoscopic spherical colloids in alternating electric fields: a dissipative particle dynamics simulationJiajia Zhou and Friederike Schmid Self-assembly of colloidal particles into strings in a homogeneous external electric or magnetic fieldFrank Smallenburg, Hanumantha Rao Vutukuri, Arnout Imhof, Alfons van Blaaderen and Marjolein Dijkstra The nature of the laning transition in two dimensionsT Glanz and H Löwen Microscopic theory for anisotropic pair correlations in driven binary mixturesMatthias Kohl, Alexei V Ivlev, Philip Brandt, Gregor E Morfill and Hartmut Löwen Dynamics of individual colloidal particles in one-dimensional random potentials: a simulation studyRichard D L Hanes and Stefan U Egelhaaf An interacting dipole model to explore broadband transverse optical bindingMichael Mazilu, Andrew Rudhall, Ewan M Wright and Kishan Dholakia Comparison of 2D melting criteria in a colloidal systemPatrick Dillmann, Georg Maret and Peter Keim Effects of confinement and external fields on structure and transport in colloidal dispersions in reduced dimensionalityD Wilms, S Deutschländer, U Siems, K Franzrahe, P Henseler, P Keim, N Schwierz, P Virnau, K Binder, G Maret and P Nielaba Stochastic transport of particles across single barriersChristian Kreuter, Ullrich Siems, Peter Henseler, Peter Nielaba, Paul Leiderer and Artur Erbe A perspective on the interfacial properties of nanoscopic liquid dropsAlexandr Malijevský and George Jackson Controlling the wetting properties of the Asakura-Oosawa model and applications to spherical confinementA Statt, A Winkler, P Virnau and K Binder Crystalline multilayers of charged colloids in soft confinement: experiment versus theoryE C Oğuz, A Reinmüller, H J Schöpe, T Palberg, R

  8. PREFACE: Introduction to the proceedings of Dynamics Days South America 2010

    Science.gov (United States)

    Macau, Elbert E. N.; Pereira, Tiago; Prado, Antonio F. B. A.; Turci, Luiz F. R.; Winter, Othon C.

    2011-03-01

    number of attendees ever. Finally, we would like to express our gratitude to all the participants for their presentations, discussions, and remarkable interactions with one another. The tireless work undertaken by all the members of the International Advisory Committee and the Organizing Committee must also be recognized. We also wish to express our deep appreciation for the Scientific Societies and Research Support Agencies which supported the conference and provided all the resources which were necessary to make this idea of a South American Dynamics Days come true. Elbert E N Macau, Tiago Pereira, Antonio F B A Prado, Luiz F R Turci, and Othon C WinterEditors Conference photograph Conference photograph Conference photograph Conference photograph International Advisory Committee Adilson E MotterNorthwestern UniversityEvanston - IL - USA Alfredo OzorioCentro Brasileiro de Pesquisas FísicasRio de Janeiro - RJ - Brazil Celso Grebogi (Chair)University of AberdeenAberdeen - UK Ed OttUniversity of MarylandCollege Park - MD - USA Epaminondas Rosa JrIllinois State UniversityNormal - IL - USA Hans Ingo WeberPontifícia Universidade CatólicaRio de Janeiro - RJ - Brazil Holger KantzMax Planck Institute for the Physics of Complex SystemsDresden - Germany Jason Gallas (Co-chair)Universidade Federal do Rio Grande do SulPorto Alegre - RS - Brazil José Roberto Rios LeiteUniv. Federal de PernanbucoRecife - PE - Brazil Jürgen KurthsPotsdam Institute for climate Impact ResearchHumboldt University, Berlin - Germany Kenneth ShowalterWest Virginia UniversityMorgantown - WV - USA Lou PecoraNaval Research LabWashington - DC - USA Luis Antonio AguirreUniversidade Federal de Minas GeraisBelo Horizonte - MG - Brazil Marcelo VianaIMPA - Instituto Nacional de Matemática Pura e AplicadaRio de Janeiro - RJ - Brazil Miguel A F SanjuánUniversidad Rey Juan CarlosMadrid - Spain Paulo Roberto de Souza MendesPontifícia Universidade CatólicaRio de Janeiro - RJ - Brazil Roland KorbeleUniversidade de

  9. The Response of the Thermosphere and Ionosphere to Magnetospheric Forcing

    Science.gov (United States)

    Rees, D.; Fuller-Rowell, T. J.

    1989-06-01

    within the polar cap, irrespective of convection pattern. Any polar cap troughs are a result of changes in neutral composition. Subauroral troughs can only develop around the summer polar region when the auroral oval is expanded so that the midnight part of the auroral oval extends into the nightside. Conditions for this situation are likely to occur preferentially in the southern polar region, due to the greater offset of the geomagnetic from geographic pole. The E-region response to geomagnetic forcing is also strong, although generally rather less marked than in the F-region, in terms of the neutral thermal and compositional response. The major feed-back between the thermosphere and ionosphere occurs due to the effects of high induced winds, since the neutral chemical changes do not significantly affect the ionospheric chemistry. Apart from localized effects such as sporadic-E layers, high-speed auroral oval winds do not cause significant vertical transport of E-region molecular species, due to rapid recombination. The most significant vertical transport effects will be in non-sunlit regions, where ion production is lowest. The dynamo effect of induced E-region winds of 200-400 m s-1 is also quite significant. Such winds reduce horizontal currents, with an implication that the FAC or Pedersen currents may also be decreased, with a possible feedback to the convection electric field. There is still relatively little data available for detailed case-study comparisons. Such studies have been quite successful in improving our understanding of the F-region behaviour, and the CEDAR initiative and programmes such as LTCS promise to extend the range of multiparameter data-sets to the E-region as well. Simulating atmospheric density and compositional structure with numerical models is one of the most testing demands. Density at a given altitude is very sensitive to the total thermospheric energy budget, and is thus liable to be the first casualty of cumulative small errors in

  10. Analysis of the HASI accelerometers data measured during the impact phase of the Huygens probe on the surface of Titan by means of a simulation with a finite-element model

    Science.gov (United States)

    Bettanini, C.; Zaccariotto, M.; Angrilli, F.

    2008-04-01

    The Huygens Atmospheric Structure Instrument (HASI) [Fulchignoni, M., Ferri, F., Angrilli, F., Bar-Nun, A., Barucci, M.A., Bianchini, G., Borucki, W., Coradini, M., Coustenis, A., Falkner, P., Flamini, E., Grard, R., Hamelin, M., Harri, A.M., Leppelmaier, G.W., Lopez-Moreno, J.J., McDonnell, J.A.M., McKay, C.P., Neubauer, F.M., Pedersen, A., Piacardi, G., Pirronello, V., Schwingenschuh, K., Seiff, A., Svedhem, H., Vanzani, V., Zarnecki, J.C., 2002. The characterisation of Titan atmosphere physical properties. Space Sci. Rev. 104, 395-431] was a very complete instrument suite installed on board the Huygens probe, the planetary lander of the Cassini Huygens Mission to Saturn system, which successfully completed its mission in January 2005. HASI comprised a set of accelerometers, temperature sensors, pressure transducers and permittivity analysers aimed at the investigation of Titan atmosphere, which were fully operative during a several hour-long parachuted descent from an altitude of 157 km to planetary surface. Accelerometers were the only instruments activated earlier, just after Cassini separation, and recorded data during all the mission phases from atmospheric entry to landing, providing essential information for elaborating probe trajectory as well as Titan atmospheric profiles [G. Colombatti, et al. Reconstruction of the trajectory of the Huygens probe using the Huygens Atmospheric Structure Instrument, this same PSS issue]. Although not specifically designed for monitoring very fast dynamic events, HASI accelerometers have also recorded the trace of probe impact with the planetary surface, building up along with the data from Huygens Surface Science Package (SSP) instrument [ Zarnecki, J.C., Leese, M.R., Garry, J.R.C., Ghafoor, N.A.L., Hathi, B., 2002. Huygens Surface Science Package. Space Sci. Rev. 104, 593-611] the only set of direct measurements of the mechanical properties of the Titan soil. Though not considered secondary with respect to SSP data, HASI

  11. In situ measurement of the Icelandic Holuhraun/ Bárðarbunga volcanic plume in an early "young state" using a LOAC

    Science.gov (United States)

    Vignelles, Damien; Roberts, Tjarda; Carboni, Elisa; Ilyinskaya, Evgenia; Dagsson Waldhauserovà, Pavla; Berthet, Gwenael; Jegou, Fabrice; Baptiste Renard, Jean; Olafsson, Haraldur; Bergsson, Baldur; Yeo, Richard; Fannar Reynisson, Njall; Grainger, Roy; Pfeffer, Melissa; Lurton, Thibaut; Duverger, Vincent; Coute, Benoit

    2016-04-01

    analysis of IASI satellite remote sensing data, thus demonstrating in-situ validation of this recent satellite algorithm (Carboni et al. 2015). This experimentation shows that under such difficult field campaign conditions (strong wind, low temperatures, only car batteries for power supply, night time and active volcano close to the launch site) it is possible to launch meteorological balloons with novel payloads to directly sample in-situ the near-source plume, determine the plume altitude, identify dynamical phases of the plume and document the size distribution of particles inside a plume which is only a quarter of an hour old. Carboni, E., Grainger, R., Walker, J., Dudhia, A., Siddans, R.: A new scheme for sulphur dioxide retrieval from IASI measurements: application to the Eyjafjallajökull eruption of April and May 2010, Atmos. Chem. Phys., 12, 11417-11434, 2012/doi:10.5194/acp-12-11417-2012, 2012. Gíslason, S.R., Stefánsdóttir, G., Pfeffer, M.A., Barsotti, S., Jóhannsson, Th., Galeczka, I., Bali, E., Sigmarsson, O., Stefánsson, A., Keller, N.S., Sigurdsson, Á., Bergsson, B., Galle, B., Jacobo, V.C., Arellano, S., Aiuppa, A., Jónasdóttir, E.B., Eiríksdóttir, E.S., Jakobsson, S., Guðfinnsson, G.H., alldórsson, S.A., Gunnarsson, H., Haddadi, B., Jónsdóttir, I., Thordarson, Th., Riishuus, M., ögnadóttir, Th., Dürig, T., Pedersen, G.B.M., Höskuldsson, Á., Gudmundsson, M.T.: Environmental pressure from the 2014-15 eruption of Bárðarbunga volcano, Iceland. Geochem. Persp. Let. 1, 84-93, 2015. Renard, J.B., Dulac, F., Berthet, G., Lurton, T., Vignelles, D., Jégou, F., Tonnelier, T., Thaury, C., Jeannot, M., Couté, B., Akiki, R., Verdier, N., Mallet, M., Gensdarmes, F., Charpentier, P., Duverger, V., Dupont, J.V., Mesmin, S., Elias, T., Crenn, V., Sciare, J., Giacomoni, J., Gobbi, M., Hamonou, E., Olafsson, H., Dagsson-Waldhauserova, P., Camy-Peyret, C., Mazel, C., Décamps, T., Piringer, M., Surcin, J., and Daugeron, D.: LOAC: a small aerosol optical

  12. Investigating actinide compounds within a hybrid MCSCF-DFT model

    International Nuclear Information System (INIS)

    Fromager, E.; Jensen, H.J.A.; Wahlin, P.; Real, F.; Wahlgren, U.

    2007-01-01

    definition of an optimal μ opt parameter [3], independent of the approximate short-range functional and the approximate (MCSCF) wave function, is applied in this work. Recently reviewed calculations on light elements yielded μ opt ∼ 0.4 a.u [3], which is in agreement with previous calibration studies. A new numerical investigation of μ opt is now presented for actinides. A test set consisting of ThO 2 , PaO 2 + , UO 2 2+ , UCO and UN 2 (representing cases without significant static correlation) as well as NpO 2 3+ and PuO 2 4+ (representing cases with significant static correlation) has been considered. The bending problem of NpO 2 3+ and PuO 2 4+ observed in KS-DFT(B3LYP) is then addressed within the hybrid MCSCF-DFT approach. Calculations have been performed at the scalar relativistic level with the MCSCF-DFT code [4] implemented in a development version of the DALTON program package [5], using short-range LDA and PBE-type functionals [3. References [1] M. Straka, K.G. Dyall, and P. Pyykko, Theor. Chem. Acc., 106, 393 (2001); [2] A. Savin, in Recent Developments and Applications of Modern Density Functional Theory, edited by J.M. Seminario (Elsevier, Amsterdam, 1996), p. 327; [3] E. Fromager, J. Toulouse, and H. J. Aa. Jensen, J. Chem. Phys., in press; [4] J.K. Pedersen and H.J.A. Jensen, J. Chem. Phys., submitted; [5] T. Helgaker, H.J. Aa. Jensen, P. Jorgensen, J. Oelsen, K. Ruud, H. Agren, K.L. Bak, V. Bakken, O. Christiansen, S. Coriani, et al., Dalton release 2.0 (2005), an electronic structure program, www.kjemi.uio.no/software/dalton/dalton.html

  13. Selected Abstracts of the 2nd Congress of joint European Neonatal Societies (jENS 2017; Venice (Italy; October 31-November 4, 2017; Session "Neonatal Gastrointestinal Physiology and NEC"

    Directory of Open Access Journals (Sweden)

    --- Various Authors

    2017-10-01

    INTESTINAL PERFORATION: A DIAGNOSTIC CHALLENGE IN THE NEWBORN • M. Branco, T. Lopes, I. Falcão, L. Pinho, C. Enes, A. Almeida, C. Carvalho, E. ProençaABS 19. OUTCOMES OF EXTREMELY LOW BIRTH WEIGHT BABIES RECEIVING SURGICAL TREATMENT FOR NECROTISING ENTEROCOLITIS • J. Ashton, C. Charlesworth, P. YajamanyamABS 20. ASSESSMENT OF ENZYMOTHERAPY EFFICACY IN CASE OF LACTASE INSUFFICIENCY IN PRETERM INFANTS • O. Vlasova, L. KoliubakinaABS 21. THE NORWEGIAN PRETERM INFANT GUT (PINGU STUDY: A METAGENOMIC APPROACH TO GUT MICROBIOTA COMPOSITION AND RESISTOME IN INFANTS SUPPLEMENTED WITH PROBIOTICS • E. Esaiassen, E. Hjerde, P. Cavanagh, T. Pedersen, J. Andresen, S. Rettedal, R. Støen, B. Nakstad, N.P. Willassen, C. KlingenbergABS 22. NECROTIZING ENTEROCOLITIS: WHAT ASPECTS IN 2017? • H. Ben Salem, I. Kasraoui, M.T. Lamouchi, E.D. Bouaicha, N. Kasdallah, S. Blibech, M. DoagiABS 23. ROUTINE PROBIOTICS FOR PRETERM NEONATES: EXPERIENCE IN A TERTIARY AUSTRALIAN NEONATAL INTENSIVE CARE UNIT • G. Deshpande, V. Shingde, L. Downe, J. Xiao, M. TaberABS 24. MATERNAL RISK FACTORS FOR NEC IN PREMATURES INFANTS WITH GA UNDER 28 WEEKS • L. Olariu, G. Olariu, S. Olariu

  14. Results of Monitoring at Olkiluoto in 2007. Hydrogeochemistry

    Energy Technology Data Exchange (ETDEWEB)

    Pitkaenen, P.; Partamies, S. (VTT, Espoo (Finland)); Lahdenperae, A.-M.; Ahokas, T.; Penttinen, T. (Poeyry Environment Oy, Vantaa (Finland)); Lehtinen, A. (Posiva Oy, Helsinki (Finland)); Pedersen, K. (Microbial Analytics Sweden AB (Sweden)); Lamminmaeki, T. (Teollisuuden Voima Oy, Olkiluoto (Finland)); Hatanpaeae, E. (Ramboll Analytics Oy, Lahti (Finland))

    2008-07-15

    . Hydrogeochemical development in them requires close monitoring in the future. The gas results also correspond very well to the baseline data suggesting no influence of ONKALO on the groundwater conditions, although gases are not considered to be as sensitive indicators of changes as dissolved solids. Groundwater sampling from ONKALO has so far not revealed notably high SO{sub 4} contents, which are relatively common in surface based sampling at 100 to 300 m depth. The number of groundwater samples and the potential sampling locations are small after excavation passed through HZ19 at about 100 m depth due to low permeability of the host rock. The 2H- and 18O- compositions in samples taken from ONK-KR3 and particularly ONK-KR4 show a tendency towards isotopic composition of Korvensuo water, suggesting that water from the reservoir may discharge in these drillholes. Earlier shallow groundwater data from bedrock between ONKALO and Korvensuo are lacking, making it impossible to evaluate if this is caused by ONKALO or if water from the reservoir has already earlier infiltrated and mixed in the shallow depths. Microbiological data obtained during the 2007 monitoring programme with three independent methods support the results that suggest the 300 m depth level in Olkiluoto to be more active with respect to microbiological processes than the depth interval between 20 and 250 m. Starting at a depth of approximately 300 m, there are steep gradients of decreasing sulphate and increasing methane concentrations with depth; together with the peaks in biomass and sulphide concentration at this depth (Pedersen 2008) these suggest that anaerobic methane oxidation may be a significant process at 300 m depth in Olkiluoto. Gefinex S400 sounding curves show slight changes in comparison with the 2004 - 2006 ARD curves. The differences may mostly be caused by the new earthwork structures or the alteration of the moisture of soil and bedrock. According to the monitoring results, decreasing resistivity

  15. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    1994-01-01

    Full Text Available -Peter Hulme, Simon Gikandi, Writing in limbo: Modernism and Caribbean literature. Ithaca: Cornell University Press, 1992. x + 260 pp. -Charles V. Carnegie, Alistair Hennessy, Intellectuals in the twentieth-century Caribbean (Volume 1 - Spectre of the new class: The Commonwealth Caribbean. London: Macmillan, 1992. xvii 204 pp. -Nigel Rigby, Anne Walmsley, The Caribbean artists movement, 1966-1972: A literary and cultural history. London: New Beacon Books, 1992. xx + 356 pp. -Carl Pedersen, Tyrone Tillery, Claude McKay: A black poet's struggle for identity. Amherst: University of Massachusetts Press, 1992. xii + 235 pp. -Simone Dreyfus, Irving Rouse, The Tainos: Rise and decline of the people who greeted Columbus. New Haven: Yale University Press, 1992. xii + 211 pp. -Louis Allaire, Antonio M. Stevens-Arroyo, Cave of the Jagua: The mythological world of the Taino. Alburquerque: University of New Mexico Press, 1988. xiii + 282 pp. -Irving Rouse, William F. Keegan, The people who discovered Columbus: The prehistory of the Bahamas. Gainesville: University of Florida Press, 1992. xx + 279 pp. -Neil L. Whitehead, Philip P. Boucher, Cannibal encounters: Europeans and Island Caribs, 1492-1763. Baltimore: John Hopkins University Press, 1992. xii + 217 pp. -Peter Kloos, Kaliña, des amérindiens à Paris: Photographies du prince Roland. Présentées par Gérard Collomb. Paris: Créaphis, 1992. 119 pp. -Maureen Warner-Lewis, Alan Gregor Cobley ,The African-Caribbean connection: Historical and cultural perspectives. Bridgetown, Barbados: Department of History, University of the West Indies, Cave Hill, 1990. viii + 171 pp., Alvin Thompson (eds -H. Hoetink, Jean-Luc Bonniol, La couleur comme maléfice: une illustration créole de la généalogie des 'Blancs' et des 'Noirs'. Paris: Albin Michel, 1992. 304 pp. -Michael Aceto, Richard Price ,Two evenings in Saramaka. Chicago and London: University of Chicago Press, 1991. xvi + 417 pp., Sally Price (eds -Jorge P

  16. EDITORIAL: Wind energy

    Science.gov (United States)

    Mann, Jakob; Nørkær Sørensen, Jens; Morthorst, Poul-Erik

    2008-01-01

    addressed within the issue is how much conventional power production can be replaced by the ceaseless wind, with the question of how Greece's target of 29% renewables by 2020 is to be met efficiently. Other topics include an innovative way to determine the power curve of a turbine experimentally more accurately, the use of fluid dynamics tools to investigate the implications of placing vortex generators on wind turbine blades (thereby possibly improving their efficiency) and a study of the perception of wind turbine noise. It turns out that a small but significant fraction of wind turbine neighbours feel that turbine generated noise impairs their ability to rest. The annoyance is correlated with a negative attitude towards the visual impact on the landscape, but what is cause and effect is too early to say. As mentioned there is a rush for wind turbines in many countries. However, this positive development for the global climate is currently limited by practical barriers. One bottleneck is the difficulties for the sub-suppliers of gears and other parts to meet the demand. Another is the difficulties to meet the demand for engineers specialized in wind. For that reason the Technical University of Denmark (DTU) recently launched the world's first Wind Energy Masters Program. Here and elsewhere in the world of wind education and research we should really speed up now, as our chances of contributing to emission free energy production and a healthier global climate have never been better. Focus on Wind Energy Contents The articles below represent the first accepted contributions and further additions will appear in the near future. Wind turbines—low level noise sources interfering with restoration? Eja Pedersen and Kerstin Persson Waye On the effect of spatial dispersion of wind power plants on the wind energy capacity credit in Greece George Caralis, Yiannis Perivolaris, Konstantinos Rados and Arthouros Zervos Large-eddy simulation of spectral coherence in a wind turbine wake

  17. EDITORIAL: Focus on Cold and Ultracold Molecules FOCUS ON COLD AND ULTRACOLD MOLECULES

    Science.gov (United States)

    Carr, Lincoln D.; Ye, Jun

    2009-05-01

    Robin Côté Single-photon molecular cooling Edvardas Narevicius, S Travis Bannerman and Mark G Raizen Quantum simulations of extended Hubbard models with dipolar crystals M Ortner, A Micheli, G Pupillo and P Zoller Collisional and molecular spectroscopy in an ultracold Bose-Bose mixture G Thalhammer, G Barontini, J Catani, F Rabatti, C Weber, A Simoni, F Minardi and M Inguscio Multi-channel modelling of the formation of vibrationally cold polar KRb molecules Svetlana Kotochigova, Eite Tiesinga and Paul S Julienne Formation of ultracold, highly polar X1Σ+ NaCs molecules C Haimberger, J Kleinert, P Zabawa, A Wakim and N P Bigelow Quantum polarization spectroscopy of correlations in attractive fermionic gases T Roscilde, M Rodríguez, K Eckert, O Romero-Isart, M Lewenstein, E Polzik and A Sanpera Inelastic semiclassical collisions in cold dipolar gases Michael Cavagnero and Catherine Newell Quasi-universal dipolar scattering in cold and ultracold gases J L Bohn, M Cavagnero and C Ticknor Stark deceleration of lithium hydride molecules S K Tokunaga, J M Dyne, E A Hinds and M R Tarbutt Molecular vibrational cooling by optical pumping with shaped femtosecond pulses D Sofikitis, S Weber, A Fioretti, R Horchani, M Allegrini, B Chatel, D Comparat and P Pillet Deeply bound ultracold molecules in an optical lattice Johann G Danzl, Manfred J Mark, Elmar Haller, Mattias Gustavsson, Russell Hart, Andreas Liem, Holger Zellmer and Hanns-Christoph Nägerl Toward the production of quantum degenerate bosonic polar molecules, 41K87Rb K Aikawa, D Akamatsu, J Kobayashi, M Ueda, T Kishimoto and S Inouye Influence of a Feshbach resonance on the photoassociation of LiCs J Deiglmayr, P Pellegrini, A Grochola, M Repp, R Côté, O Dulieu, R Wester and M Weidemüller The kinematic cooling of molecules with laser-cooled atoms Ken Takase, Larry A Rahn, David W Chandler and Kevin E Strecker Coherent collapses of dipolar Bose-Einstein condensates for different trap geometries J Metz, T Lahaye, B Fr

  18. FOREWORD: Computational methodologies for designing materials Computational methodologies for designing materials

    Science.gov (United States)

    Rahman, Talat S.

    2009-02-01

    state. The contribution by Langreth and co-workers [3] summarizes their recent efforts at incorporating non-local van der Waals forces into DFT so as to make it suitable for accurate description of the physical and chemical properties of the ground state of sparse/soft matter. Their applications to molecules, layered systems, and hybrid structures are promising and mark the beginning of work in another important set of materials for which insights could be obtained from DFT. The paper here by Tang et al [4] focuses on the usage of grid-based methods for calculations of local charge densities. The virtue of the method is that charge densities are not confined to a lattice. Finally, as applications of DFT, the article by Groß [5] is representative of the usage of DFT in tailoring the electronic structures of surface alloys and other nanostructures, while the contribution by Bohnen et al [6] is a further example of the applicability of density functional perturbation theory in accurate descriptions of the lattice dynamics of functional nanomaterials such as carbon nanotubes. For the modeling of amorphous materials, Biswas and co-workers [7] present a review of methods such as the reverse Monte Carlo (RMC) and 'experimentally constrained molecular relaxation' models which impose constraints to ensure that the final model meets a priori requirements on structure, topology, chemical ordering, etc. In a similar vein, the papers by Rossi and Ferrando [8] and Rogan et al [9] , summarize advances in the determination of the equilibrium structure of nanoparticles and nanoalloys through global optimization strategies such as genetic and Basin-hopping approaches, diversity-driven unbiased searches and the conformational space annealing method. Structure determination itself relies on the knowledge of the system energy landscape, the saddle points and the transition states. In this issue the work of Pedersen et al [10] is an example of how a saddle point search method can be used to

  19. PREFACE Proceedings of the XIV International Conference on Small-Angle Scattering, SAS-2009

    Science.gov (United States)

    King, Stephen; Terrill, Nicholas

    2010-10-01

    scientific heart of the conference comprised 10 plenary sessions, interspersed by 39 'themed' parallel sessions, 2 poster sessions, an afternoon tour of Diamond and ISIS, and a week-long exhibition. There were 144 contributed oral presentations and 308 poster presentations across a total of 21 themes. Over half of all presentations fell under 6 themes: biological systems, colloids and solutions, instrumentation, kinetic and time-resolved measurements, polymers, and surfaces and interfaces. The importance of SAS techniques to the study of biology, materials science and soft matter/nanoscience is clear. The plenary presentations, which covered topics as diverse as advanced analysis techniques, biology, green chemistry, materials science and surfaces, were delivered by Frank Bates, Minnesota, USA, Peter Fratzl, MPI Golm, Germany, Buxing Han, Bejing, China, Julia Kornfield, CIT, USA, Jan Skov Pedersen, Aarhus, Denmark, Moonhor Ree, Pohang, Korea, Mitsuhiro Shibayama, Tokyo, Japan, Robert Thomas, Oxford, UK, Jill Trewhella, Sydney, Australia, and Thomas Zemb, ICSM Bagnols, France. Instigated by representatives of the Belgian and Dutch SAS communities one parallel session was dedicated to a tribute for Michel Koch, the pioneer of so many novel applications of SAXS, who retired after 30 years at the EMBL Hamburg in late 2006. With a supporting cast that included Wim Bras, ESRF, France, Tony Ryan, Sheffield, UK and Joe Zaccai, ILL,France, and watched by former colleague André Gabriel, Michel treated the audience to a fascinating - and at times light-hearted - retrospective of the evolution of synchrotron SAXS. Another parallel session was devoted to the work of the canSAS (Collective Action for Nomadic Small-Angle Scatterers) network of large-facility representatives and instrument scientists in areas such as data file formats, intensity calibration and software development. For further information see http://www.smallangles.net/wgwiki/index.php/canSAS_Working_Groups. A total of

  20. Selected Abstracts of the 2nd Congress of joint European Neonatal Societies (jENS 2017; Venice (Italy; October 31-November 4, 2017; Session "Neurology and Follow-up"

    Directory of Open Access Journals (Sweden)

    --- Various Authors

    2017-10-01

    Full Text Available Selected Abstracts of the 2nd Congress of joint European Neonatal Societies (jENS 2017; Venice (Italy; October 31-November 4, 201758th ESPR Annual Meeting, 7th International Congress of UENPS, 3rd International Congress of EFCNIORGANIZING INSTITUTIONSEuropean Society for Paediatric Research (ESPR, European Society for Neonatology (ESN, Union of European Neonatal & Perinatal Societies (UENPS, European Foundation for the Care of Newborn Infants (EFCNIORGANIZING COMMITTEELuc Zimmermann (President of ESPR, Morten Breindahl (President of ESN, Manuel Sánchez Luna (President of UENPS, Silke Mader (Chairwoman of the Executive Board and Co-Founder of EFCNISCIENTIFIC COMMITTEEVirgilio P. Carnielli (Congress President Chair, Pierre Gressens (Past Scientific President, Umberto Simeoni, Manon Benders, Neil Marlow, Ola D. Saugstad, Petra Hüppi, Agnes van den HoogenSession "Neurology and Follow-up"ABS 1. PRETERM BIRTH AND THE TIMING OF PUBERTY • E. James, C. Wood, H. Nair, T. WilliamsABS 2. NEONATAL PAIN, OPIOID AND ANAESTHETIC EXPOSURE; WHAT REMAINS IN THE HUMAN BRAIN AFTER THE WHEELS OF TIME? • G.E. van den Bosch, D. Tibboel, J.C. de Graaff, H. El Marroun, A. van der Lugt, T. White, M. van DijkABS 3. DEPRESSION DURING PREGNANCY AND DNA METHYLATION CHANGES IN CORD BLOOD • A.-C. Viuff, G. Sharp, D. Raj, K.J. Kyng, L.H. Pedersen, T.B. Henriksen, C.L. ReltonABS 4. PREVENTION OF CEREBRAL PALSY: FEASIBILITY OF UMBILICAL CORD BLOOD STEM CELLS AND UMBILICAL CORD MESENCHYMAL STROMAL CELLS • H. Shintaku, M. Nabetani, T. Hamazaki, S. Kusuda, M. Tamura, S. Watabe, M. Hayakawa, Y. Sato, M. Tsuji, A. Taguchi, H. Ichiba, O. Akira, R. Mori, A.Taki, T. Mukai, T. Nagamura-InoueABS 5. NO GENDER-RELATED DIFFERENCES IN FETAL CORPUS CALLOSUM THICKNESS: IN-UTERO MRI STUDY • R. Bercovitz, R. Achiron, C. Hoffmann, A. AchironABS 6. NEUROMOTOR PROFILE OF HIGH-RISK INFANTS AT TERM OR NEAR TERM • I. Ereno, W.Y. TehABS 7. THE PREDICTIVE VALUE OF SEVERE BRONCHOPULMONARY

  1. An estimation of Central Iberian Peninsula atmospheric δ13C and water δD in the Upper Cretaceous using pyrolysis compound specific isotopic analysis (Py-CSIA) of a fossil conifer.

    Science.gov (United States)

    González-Pérez, José A.; Jiménez-Morillo, Nicasio T.; De la Rosa, José M.; Almendros, Gonzalo; González-Vila, Francisco J.

    2015-04-01

    /alkene series in the range C24-C29 (δD = -124.44±5.2‰). This was taken as a proxy to infer the original H isotopic signal of water in the area in the Upper Cretaceous. Poole et al. (2004) proposed that δDpalaeowarter= δDC24-C29 n-alkanes + 100 giving a value for plaeowater δD = -24.44±5.2‰. This indicates that 75 Mya our plant probably uptake deuterium enriched rain water that again points to warm growing environmental conditions. (1) Gómez, B.; Martín-Closas C.; Brale G.; Solé de Porta N.; Thévenard F.; Guignard G. Paleontology 2002 45, 997-1036. (2) Nguyen Tu, T.T.; Kvaček, J.; Uličnỷ, D.; Bocherens, H.; Mariotti, A.; Broutin, J. Palaeogeogr. Palaeoclimatol. Palaeoecol. 2002 183, 43-70. (3) Almendros, G.; Álvarez-Ramis, C.; Polo, A. Revista de la Real Academia de Ciencias Exactas, Físicas y Naturales 1982 76, 285-302. (4) Dabin, B. Chah. ORSTOM Ser. Pedol. 1976 4, 287-297. (5) Schnitzer, M.; Khan, S.U. Humic Substances in the Environment. Marcel Dekker Inc. 1972, New York, N.Y. (6) Dorado, E.; Polo. A. An. Edafol. Agrobiol. 1976 55, 723-732. (7) Bocherens, H.; Friis, E.M.; Mariotti, A.; Pedersen, K.R. Lethaia 1993 26, 347-358. (8) Nguyen Tu, T.T.; Bocherens, H.; Mariotti, A.; Baudin, F.; Pons, D.; Broutin, J.; Derenne, S.; Largeau C. Palaeogeogr. Palaeoclimatol. Palaeoecol. 1999 145, 79-93. (9) Aucour, A-.M.; Gomez, B.; Sheppard, S.M.F., Thévenard, F. Palaeogeogr. Palaeoclimatol. Palaeoecol. 2008 257, 462-473. (10) Michener, N.; Lajtha K. (Eds). Stable Isotopes in Ecology and Environmental Science (2nd Ed) 2007 Blackwell Publishing. (11) Poole, I., van Bergen, P.F.; Kool, K.; Schouten , S.; Cantrill, D. J. Org. Geochem. 2004 35, 1261-1274. (12) Gerber, S.; Joos, F.; Brügger, P.; Stocker, T.F.; Mann, M.E.; Sitch, S.; Scholze, M. Clim. Dyn. 2003 20, 281-299, 2003 (13) Pedentchouk, N.; Freeman, K.H.; Harris, N.B. Geochim. Cosmochim. Acta 2006 70, 2063-2072. (14) Radke, J.; Bechtel, A.; Gaupp, R.; Püttmann, W.; Schwark, L.; Sachse D.; Gleixner, G. Geochim

  2. EDITORIAL Proceedings of the XIV International Conference on Small-Angle Scattering, SAS-2009

    Science.gov (United States)

    Ungar, Goran; Heenan, Richard

    2010-10-01

    There are 52 papers in these Proceedings. The papers are divided into 10 thematic sections and a section for invited papers and reviews. The sections and the respective section editors are given below. Section Editor(s) Invited Papers and Reviews Peter Griffiths, Wim Bras, Rudolf Winter Beamlines and Instrumentation Elliot Gilbert, Wim Bras, Nigel Rhodes Theory, Data processing and Modelling Jan Skov Pedersen, Carlo Knupp Biological Systems and Membranes Richard Heenan, Cameron Neylon Ceramics, Glasses and Porous Materials Rudolf Winter Colloids and Solutions Peter Griffiths Hierarchical Structures and Fibres Steve Eichhorn, Karen Edler Metallic and Magnetic Systems Armin Hoell Polymers Patrick Fairclough Time resolved Diffraction, Kinetic and Dynamical Studies João Cabral, Christoph Rau We are grateful to all section editors and the many anonymous referees for their invaluable effort which made the publication of the Proceedings possible. The refereeing process was strict and thorough, some papers were rejected and most were improved. The resulting compendium gives a good overview of recent developments in small-angle X-ray and neutron scattering theory, application, methods of analysis and instrumentation. Thus it should be a useful source of reference for a number of years to come. The papers are a good reflection of the material presented at the meeting. Because of the general high quality of the articles, it was difficult to decide which to highlight and be fair to all contributors. The following in particular have caught the attention of the editors. Highlighted papers A statistical survey of publications reporting the application of SAXS and SANS by Aldo Craievich (paper 012003) is recommended reading for anyone needing convincing about the vibrancy of this scientific field and the ever expanding use of these techniques. Two aspects of coherent X-ray scattering, made available by the advent of the 3rd generation synchrotron sources, are discussed in the

  3. Cognitive deficits in bipolar disorders: Implications for emotion.

    Science.gov (United States)

    Lima, Isabela M M; Peckham, Andrew D; Johnson, Sheri L

    2018-02-01

    Prominent cognitive deficits have been documented in bipolar disorder, and multiple studies suggest that these deficits can be observed among non-affected first-degree relatives of those with bipolar disorder. Although there is variability in the degree of cognitive deficits, these deficits are robustly relevant for functional outcomes. A separate literature documents clear difficulties in emotionality, emotion regulation, and emotion-relevant impulsivity within bipolar disorder, and demonstrates that these emotion-relevant variables are also central to outcome. Although cognitive and emotion domains are typically studied independently, basic research and emergent findings in bipolar disorder suggest that there are important ties between cognitive deficits and the emotion disturbances observed in bipolar disorder. Understanding these relationships has relevance for fostering more integrative research, for clarifying relevant aspects related to functionality and vulnerability within bipolar disorder, and for the development of novel treatment interventions. Bipolar disorder (BD) is a severe psychiatric illness that has been ranked as one of the 20 leading medical causes of disability (WHO, 2011). BD has been shown to be the psychiatric disorder with the highest rates of completed suicide across two major cohort studies (Ilgen et al., 2010; Nordentoft, Mortensen, & Pedersen, 2011). In a cross-national representative sample, one in four persons diagnosed with bipolar I disorder reported a suicide attempt (Merikangas et al., 2011). Rates of relapse remain high despite available treatments (Gitlin, Swendsen, Heller, & Hammen, 1995), and in the year after hospitalization for manic episode, two-thirds of patients do not return to work (Strakowski et al., 1998). Poverty, homelessness, and incarceration are all too common (Copeland et al., 2009). Despite the often poor outcomes, there is also evidence for outstanding accomplishments and creativity among those with milder

  4. Producing Light Oil from a Frozen Reservoir: Reservoir and Fluid Characterization of Umiat Field, National Petroleum Reserve, Alaska

    Energy Technology Data Exchange (ETDEWEB)

    Hanks, Catherine

    2012-12-31

    then compared to theoretical Umiat composition derived using the Pedersen method with original Umiat fluid properties published in the original reports. This comparison allowed estimation of the ‘lost’ light hydrocarbon fractions. An Umiat 'dead' oil sample then could be physically created by adding the lost light ends to the weatherized Umiat dead oil sample. This recreated sample was recombined with solution gas to create a 'pseudo-live' Umiat oil sample which was then used for experimental PVT and phase behavior studies to determine fluid properties over the range of reservoir pressures and temperatures. The phase behavior of the ‘pseudo-live’ oil was also simulated using the Peng- Robinson equations of state (EOS). The EOS model was tuned with measured experimental data to accurately simulate the differential liberation tests in order to obtain the necessary data for reservoir simulation studies, including bubble point pressure and oil viscosity. The bubble point pressure of the reconstructed Umiat oil is 345 psi, suggesting that maintenance of reservoir pressures above that pressure will be important for the any proposed production technique. A major part of predicting how the Umiat reservoir will perform is determining the relative permeability of oil in the presence of ice. Early in the project, UAF work on samples of the Umiat reservoir indicated that there is a significant reduction in the relatively permeability of oil in the presence of ice. However, it was not clear as to why this reduction occurred or where the ice resided. To explore this further, additional experimental and theoretical work was conducted. Core flood experiments were performed on two clean Berea sandstone cores under permafrost conditions to determine the relative permeability to oil (kro) over a temperature range of 23ºC to - 10ºC and for a range of connate water salinities. Both cores showed maximum reduction in relative permeability to oil when saturated