WorldWideScience

Sample records for hit-to-kill missile defense

  1. Optimal Fixed-Interval Integrated Guidance-Control Laws for Hit-to-Kill Missiles

    National Research Council Canada - National Science Library

    Menon, P. K; Sweriduk, G. D; Ohlmeyer, E. J

    2003-01-01

    Due to their potential for reducing the weapon size and efficiency, design methods for realizing hit-to- kill capabilities in missile systems are of significant research interest in the missile flight control community...

  2. Missile Defense: Ballistic Missile Defense System Testing Delays Affect Delivery of Capabilities

    Science.gov (United States)

    2016-04-28

    Page 1 GAO-16-339R Ballistic Missile Defense 441 G St. N.W. Washington, DC 20548 April 28, 2016 Congressional Committees Missile Defense... Ballistic Missile Defense System Testing Delays Affect Delivery of Capabilities For over half a century, the Department of Defense (DOD) has been...funding efforts to develop a system to detect, track, and defeat enemy ballistic missiles. The current system—the Ballistic Missile Defense System

  3. Ballistic missile defense effectiveness

    Science.gov (United States)

    Lewis, George N.

    2017-11-01

    The potential effectiveness of ballistic missile defenses today remains a subject of debate. After a brief discussion of terminal and boost phase defenses, this chapter will focus on long-range midcourse defenses. The problems posed by potential countermeasures to such midcourse defenses are discussed as are the sensor capabilities a defense might have available to attempt to discriminate the actual missile warhead in a countermeasures environment. The role of flight testing in assessing ballistic missile defense effectiveness is discussed. Arguments made about effectiveness by missile defense supporters and critics are summarized.

  4. Strategic Missile Defense & Nuclear Deterrence

    Science.gov (United States)

    Grego, Laura

    The United States has pursued defenses against nuclear-armed long-range ballistic missiles since at least the 1950s. At the same time, concerns that missile defenses could undermine nuclear deterrence and potentially spark an arms race led the United States and Soviet Union to negotiate limits on these systems. The 1972 Anti-Ballistic Missile Treaty constrained strategic missile defenses for thirty years. After abandoning the treaty in 2002, President George W. Bush began fielding the Ground-based Midcourse Defense (GMD) homeland missile defense system on an extremely aggressive schedule, nominally to respond to threats from North Korea and Iran. Today, nearly fifteen years after its initial deployment, the potential and the limits of this homeland missile defense are apparent. Its test record is poor and it has no demonstrated ability to stop an incoming missile under real-world conditions. No credible strategy is in place to solve the issue of discriminating countermeasures. Insufficient oversight has not only exacerbated the GMD system's problems, but has obscured their full extent, which could encourage politicians and military leaders to make decisions that actually increase the risk of a missile attack against the United States. These are not the only costs. Both Russia and China have repeatedly expressed concerns that U.S. missile defenses adversely affect their own strategic capabilities and interests, particularly taken in light of the substantial US nuclear forces. This in turn affects these countries' nuclear modernization priorities. This talk will provide a technical overview of the US strategic missile defense system, and how it relates to deterrence against non-peer adversaries as well as how it affects deterrence with Russia and China and the long-term prospects for nuclear reductions

  5. Missile defense in the United States

    OpenAIRE

    Heurlin, Bertil

    2004-01-01

    The basic arguments of this paper are, first, that the current US-missile defense, being operative from fall 2004, is based upon the former experiences with missile defense, second, that missile defense closely associated with weapons of mass destruction has gained the highest priority in American national security policy due to the 9.11 attacks, and third, that the superior argument for establishing an American missile defense is to maintain global, long term political-strategic superiority....

  6. Guidance Optimization for Tactical Homing Missiles and Air Defense Systems

    Directory of Open Access Journals (Sweden)

    Yunes Sh. ALQUDSI

    2018-03-01

    Full Text Available The aim of this paper is to develop a functional approach to optimize the engagement effectiveness of the tactical homing missiles and air defense systems by utilizing the differential geometric concepts. In this paper the engagement geometry of the interceptor and the target is developed and expressed in differential geometric terms in order to demonstrate the possibilities of the impact triangles and specify the earliest interception based on the direct intercept geometry. Optimizing the missile heading angle and suitable missile velocity against the target velocity is then examined to achieve minimum missile latax, minimum time-to-go (time-to-hit and minimum appropriate missile velocity that is guaranteed a quick and precise interception for the given target. The study terminates with different scenarios of engagement optimization with two-dimensional simulation to demonstrate the applicability of the DG approach and to show its properties.

  7. Cruise Missile Defense

    National Research Council Canada - National Science Library

    Hichkad, Ravi R; Bolkcom, Christopher

    2005-01-01

    Congress has expressed interest in cruise missile defense for years. Cruise missiles (CMs) are essentially unmanned attack aircraft -- vehicles composed of an airframe, propulsion system, guidance system, and weapons payload...

  8. Cruise Missile Defense

    National Research Council Canada - National Science Library

    Hichkad, Ravi R; Bolkcom, Christopher

    2004-01-01

    Congress has expressed interest in cruise missile defense for years. Cruise missiles (CMs) are essentially unmanned attack aircraft -- vehicles composed of an airframe, propulsion system, guidance system, and weapons payload...

  9. How to optimize joint theater ballistic missile defense

    OpenAIRE

    Diehl, Douglas D.

    2004-01-01

    Approved for public release, distribution is unlimited Many potential adversaries seek, or already have theater ballistic missiles capable of threatening targets of interest to the United States. The U.S. Missile Defense Agency and armed forces are developing and fielding missile interceptors carried by many different platforms, including ships, aircraft, and ground units. Given some exigent threat, the U.S. must decide where to position defensive platforms and how they should engage poten...

  10. Ballistic Missile Defense in Europe

    OpenAIRE

    Sarihan, Ali; Bush, Amy; Summers, Lawrence; Thompson, Brent; Tomasszewski, Steven

    2009-01-01

    This paper will build on ballistic missile defense in Europe. In the first part, a brief historical overview will place the current public management issue into light. This is followed by a discussion of the main actors in the international debate, the problems that arise and the available options and recommendations to address missile defense. In the second part, differences between George W. Bush and Barack H. Obama will analyze under the title “Ballistic Missile Defense in Europe: Evolving...

  11. Ballistic Missile Defense

    OpenAIRE

    Mayer, Michael

    2011-01-01

    At the 2010 NATO summit in Lisbon, the alliance decided to move forward on the development of a territorial ballistic missile defense (BMD) system and explore avenues for cooperation with Russia in this endeavor. Substantial progress on BMD has been made over the past decade, but some questions remain regarding the ultimate strategic utility of such a system and whether its benefi ts outweigh the possible opportunity costs. Missile defense has been a point of contention between the US and its...

  12. The probability of a tornado missile hitting a target

    International Nuclear Information System (INIS)

    Goodman, J.; Koch, J.E.

    1983-01-01

    It is shown that tornado missile transportation is a diffusion Markovian process. Therefore, the Green's function method is applied for the estimation of the probability of hitting a unit target area. This propability is expressed through a joint density of tornado intensity and path area, a probability of tornado missile injection and a tornado missile height distribution. (orig.)

  13. Cost of space-based laser ballistic missile defense.

    Science.gov (United States)

    Field, G; Spergel, D

    1986-03-21

    Orbiting platforms carrying infrared lasers have been proposed as weapons forming the first tier of a ballistic missile defense system under the President's Strategic Defense Initiative. As each laser platform can destroy a limited number of missiles, one of several methods of countering such a system is to increase the number of offensive missiles. Hence it is important to know whether the cost-exchange ratio, defined as the ratio of the cost to the defense of destroying a missile to the cost to the offense of deploying an additional missile, is greater or less than 1. Although the technology to be used in a ballistic missile defense system is still extremely uncertain, it is useful to examine methods for calculating the cost-exchange ratio. As an example, the cost of an orbiting infrared laser ballistic missile defense system employed against intercontinental ballistic missiles launched simultaneously from a small area is compared to the cost of additional offensive missiles. If one adopts lower limits to the costs for the defense and upper limits to the costs for the offense, the cost-exchange ratio comes out substantially greater than 1. If these estimates are confirmed, such a ballistic missile defense system would be unable to maintain its effectiveness at less cost than it would take to proliferate the ballistic missiles necessary to overcome it and would therefore not satisfy the President's requirements for an effective strategic defense. Although the method is illustrated by applying it to a space-based infrared laser system, it should be straightforward to apply it to other proposed systems.

  14. HOMA: Israel's National Missile Defense Strategy (Abridged Version)

    National Research Council Canada - National Science Library

    Lailari, Guermantes

    2002-01-01

    ... (Hebrew for Fortress Wall), Chapter 1 discusses the fundamentals of missile defense and the reason why Israel's missile defense system affects US national security interests, Chapter 2 describes Israel's missile defense...

  15. Information Management Principles Applied to the Ballistic Missile Defense System

    National Research Council Canada - National Science Library

    Koehler, John M

    2007-01-01

    .... Similarly several military systems with the single mission of missile defense have evolved in service stovepipes, and are now being integrated into a national and global missile defense architecture...

  16. Cost Effective Regional Ballistic Missile Defense

    Science.gov (United States)

    2016-02-16

    deploying advanced air defense systems18, such as the Russian S-300 and S-500, and concealing them in hardened, camouflaged sites, such as extensive... Russian objections to the European Phased Adaptive Approach (EPAA) and fund homeland defense priorities.39 Furthermore, the PTSS system was also... Theatre Ballistic Missile Defence Capability Becomes Operational,” Jane’s Missiles & Rockets, 1 February 2011. 55 Joseph W. Kirschbaum, REGIONAL MISSILE

  17. 75 FR 52732 - Renewal of Department of Defense Federal Advisory Committee; Missile Defense Advisory Committee

    Science.gov (United States)

    2010-08-27

    ... Committee; Missile Defense Advisory Committee AGENCY: Department of Defense (DoD). ACTION: Renewal of..., the Department of Defense gives notice that it is renewing the charter for the Missile Defense... Director, Missile Defense Agency, independent advice and recommendations on all matters relating to missile...

  18. Japan and Ballistic Missile Defense

    National Research Council Canada - National Science Library

    Swaine, Michael

    2001-01-01

    Spurred by a perceived growing ballistic missile threat from within the Asia-Pacific region and requests from the United States to support research and development on components of a missile defense...

  19. 2015 Assessment of the Ballistic Missile Defense System (BMDS)

    Science.gov (United States)

    2016-04-01

    Director, Operational Test and Evaluation 2015 Assessment of the Ballistic Missile Defense System (BMDS...Evaluation (DOT&E) as they pertain to the Ballistic Missile Defense System (BMDS). Congress specified these requirements in the fiscal year 2002 (FY02...systems are the Ground-based Midcourse Defense (GMD), Aegis Ballistic Missile Defense (Aegis BMD), Terminal High-Altitude Area Defense (THAAD), and

  20. Space-based ballistic-missile defense

    International Nuclear Information System (INIS)

    Bethe, H.A.; Garwin, R.L.; Gottfried, K.; Kendall, H.W.

    1984-01-01

    This article, based on a forthcoming book by the Union for Concerned Scientists, focuses on the technical aspects of the issue of space-based ballistic-missile defense. After analysis, the authors conclude that the questionable performance of the proposed defense, the ease with which it could be overwhelmed or circumvented, and its potential as an antisatellite system would cause grievous damage to the security of the US if the Strategic Defense Initiative were to be pursued. The path toward greater security lies in quite another direction, they feel. Although research on ballistic-missile defense should continue at the traditional level of expenditure and within the constraints of the ABM Treaty, every effort should be made to negotiate a bilateral ban on the testing and use of space weapons. The authors think it is essential that such an agreement cover all altitudes, because a ban on high-altitude antisatellite weapons alone would not viable if directed energy weapons were developed for ballistic-missile defense. Further, the Star Wars program, unlikely ever to protect the entire nation against a nuclear attack, would nonetheless trigger a major expansion of the arms race

  1. Detection technique of targets for missile defense system

    Science.gov (United States)

    Guo, Hua-ling; Deng, Jia-hao; Cai, Ke-rong

    2009-11-01

    Ballistic missile defense system (BMDS) is a weapon system for intercepting enemy ballistic missiles. It includes ballistic-missile warning system, target discrimination system, anti-ballistic-missile guidance systems, and command-control communication system. Infrared imaging detection and laser imaging detection are widely used in BMDS for surveillance, target detection, target tracking, and target discrimination. Based on a comprehensive review of the application of target-detection techniques in the missile defense system, including infrared focal plane arrays (IRFPA), ground-based radar detection technology, 3-dimensional imaging laser radar with a photon counting avalanche photodiode (APD) arrays and microchip laser, this paper focuses on the infrared and laser imaging detection techniques in missile defense system, as well as the trends for their future development.

  2. 75 FR 43156 - Federal Advisory Committee; Missile Defense Advisory Committee

    Science.gov (United States)

    2010-07-23

    ... DEPARTMENT OF DEFENSE Office of the Secretary Federal Advisory Committee; Missile Defense Advisory Committee AGENCY: Missile Defense Agency (MDA), DoD. ACTION: Notice of closed meeting. SUMMARY: Under the... Defense announces that the Missile Defense Advisory Committee will meet on August 4 and 5, 2010, in...

  3. The science, technology, and politics of ballistic missile defense

    Science.gov (United States)

    Coyle, Philip E.

    2014-05-01

    America's missile defense systems are deployed at home and abroad. This includes the Groundbased Missile Defense (GMD) system in Alaska and California, the Phased Adaptive Approach in Europe (EPAA), and regional systems in the Middle East and Asia. Unfortunately these systems lack workable architectures, and many of the required elements either don't work or are missing. Major review and reconsideration is needed of all elements of these systems. GMD performance in tests has gotten worse with time, when it ought to be getting better. A lack of political support is not to blame as the DoD spends about 10 billion per year, and proposes to add about 5 billion over the next five years. Russia objects to the EPAA as a threat to its ICBM forces, and to the extensive deployment of U.S. military forces in countries such as Poland, the Czech Republic and Romania, once part of the Soviet Union. Going forward the U.S. should keep working with Russia whose cooperation will be key to diplomatic gains in the Middle East and elsewhere. Meanwhile, America's missile defenses face an enduring set of issues, especially target discrimination in the face of attacks designed to overwhelm the defenses, stage separation debris, chaff, decoys, and stealth. Dealing with target discrimination while also replacing, upgrading, or adding to the many elements of U.S. missiles defenses presents daunting budget priorities. A new look at the threat is warranted, and whether the U.S. needs to consider every nation that possesses even short-range missiles a threat to America. The proliferation of missiles of all sizes around the world is a growing problem, but expecting U.S. missile defenses to deal with all those missiles everywhere is unrealistic, and U.S. missile defenses, effective or not, are justifying more and more offensive missiles.

  4. The science, technology, and politics of ballistic missile defense

    International Nuclear Information System (INIS)

    Coyle, Philip E.

    2014-01-01

    America's missile defense systems are deployed at home and abroad. This includes the Groundbased Missile Defense (GMD) system in Alaska and California, the Phased Adaptive Approach in Europe (EPAA), and regional systems in the Middle East and Asia. Unfortunately these systems lack workable architectures, and many of the required elements either don't work or are missing. Major review and reconsideration is needed of all elements of these systems. GMD performance in tests has gotten worse with time, when it ought to be getting better. A lack of political support is not to blame as the DoD spends about $10 billion per year, and proposes to add about $5 billion over the next five years. Russia objects to the EPAA as a threat to its ICBM forces, and to the extensive deployment of U.S. military forces in countries such as Poland, the Czech Republic and Romania, once part of the Soviet Union. Going forward the U.S. should keep working with Russia whose cooperation will be key to diplomatic gains in the Middle East and elsewhere. Meanwhile, America's missile defenses face an enduring set of issues, especially target discrimination in the face of attacks designed to overwhelm the defenses, stage separation debris, chaff, decoys, and stealth. Dealing with target discrimination while also replacing, upgrading, or adding to the many elements of U.S. missiles defenses presents daunting budget priorities. A new look at the threat is warranted, and whether the U.S. needs to consider every nation that possesses even short-range missiles a threat to America. The proliferation of missiles of all sizes around the world is a growing problem, but expecting U.S. missile defenses to deal with all those missiles everywhere is unrealistic, and U.S. missile defenses, effective or not, are justifying more and more offensive missiles

  5. The science, technology, and politics of ballistic missile defense

    Energy Technology Data Exchange (ETDEWEB)

    Coyle, Philip E. [Center for Arms Control and Non-Proliferation, Washington, DC (United States)

    2014-05-09

    America's missile defense systems are deployed at home and abroad. This includes the Groundbased Missile Defense (GMD) system in Alaska and California, the Phased Adaptive Approach in Europe (EPAA), and regional systems in the Middle East and Asia. Unfortunately these systems lack workable architectures, and many of the required elements either don't work or are missing. Major review and reconsideration is needed of all elements of these systems. GMD performance in tests has gotten worse with time, when it ought to be getting better. A lack of political support is not to blame as the DoD spends about $10 billion per year, and proposes to add about $5 billion over the next five years. Russia objects to the EPAA as a threat to its ICBM forces, and to the extensive deployment of U.S. military forces in countries such as Poland, the Czech Republic and Romania, once part of the Soviet Union. Going forward the U.S. should keep working with Russia whose cooperation will be key to diplomatic gains in the Middle East and elsewhere. Meanwhile, America's missile defenses face an enduring set of issues, especially target discrimination in the face of attacks designed to overwhelm the defenses, stage separation debris, chaff, decoys, and stealth. Dealing with target discrimination while also replacing, upgrading, or adding to the many elements of U.S. missiles defenses presents daunting budget priorities. A new look at the threat is warranted, and whether the U.S. needs to consider every nation that possesses even short-range missiles a threat to America. The proliferation of missiles of all sizes around the world is a growing problem, but expecting U.S. missile defenses to deal with all those missiles everywhere is unrealistic, and U.S. missile defenses, effective or not, are justifying more and more offensive missiles.

  6. Single-hit mechanism of tumour cell killing by radiation.

    Science.gov (United States)

    Chapman, J D

    2003-02-01

    To review the relative importance of the single-hit mechanism of radiation killing for tumour response to 1.8-2.0 Gy day(-1) fractions and to low dose-rate brachytherapy. Tumour cell killing by ionizing radiation is well described by the linear-quadratic equation that contains two independent components distinguished by dose kinetics. Analyses of tumour cell survival curves that contain six or more dose points usually provide good estimates of the alpha- and beta-inactivation coefficients. Superior estimates of tumour cell intrinsic radiosensitivity are obtained when synchronized populations are employed. The characteristics of single-hit inactivation of tumour cells are reviewed and compared with the characteristics of beta-inactivation. Potential molecular targets associated with single-hit inactivation are discussed along with strategies for potentiating cell killing by this mechanism. The single-hit mechanism of tumour cell killing shows no dependence on dose-rate and, consequently, no evidence of sublethal damage repair. It is uniquely potentiated by high linear-energy-transfer radiation, exhibits a smaller oxygen enhancement ratio and exhibits a larger indirect effect by hydroxyl radicals than the beta-mechanism. alpha-inactivation coefficients vary slightly throughout interphase but mitotic cells exhibit extremely high alpha-coefficients in the range of those observed for lymphocytes and some repair-deficient cells. Evidence is accumulating to suggest that chromatin in compacted form could be a radiation-hypersensitive target associated with single-hit radiation killing. Analyses of tumour cell survival curves demonstrate that it is the single-hit mechanism (alpha) that determines the majority of cell killing after doses of 2Gy and that this mechanism is highly variable between tumour cell lines. The characteristics of single-hit inactivation are qualitatively and quantitatively distinct from those of beta-inactivation. Compacted chromatin in tumour cells

  7. 75 FR 77849 - Closed Meeting of the Missile Defense Advisory Committee

    Science.gov (United States)

    2010-12-14

    ... DEPARTMENT OF DEFENSE Office of the Secretary Closed Meeting of the Missile Defense Advisory Committee AGENCY: Department of Defense; Missile Defense Agency (MDA). ACTION: Notice. SUMMARY: Under the... Defense announces that the following Federal advisory committee meeting of the Missile Defense Advisory...

  8. 75 FR 77848 - Closed Meeting of the Missile Defense Advisory Committee

    Science.gov (United States)

    2010-12-14

    ... DEPARTMENT OF DEFENSE Office of the Secretary Closed Meeting of the Missile Defense Advisory Committee AGENCY: Department of Defense; Missile Defense Agency (MDA). ACTION: Notice. SUMMARY: Under the... Defense announces that the following Federal advisory committee meeting of the Missile Defense Advisory...

  9. 77 FR 34357 - Missile Defense Advisory Committee; Notice of Closed Meeting

    Science.gov (United States)

    2012-06-11

    ... DEPARTMENT OF DEFENSE Office of the Secretary Missile Defense Advisory Committee; Notice of Closed Meeting AGENCY: Missile Defense Agency (MDA), Department of Defense. ACTION: Notice of closed meeting... Missile Defense Advisory Committee will take place. DATES: Tuesday, June 12, 2012 through Wednesday, June...

  10. 76 FR 71556 - Missile Defense Advisory Committee; Notice of Closed Meeting

    Science.gov (United States)

    2011-11-18

    ... DEPARTMENT OF DEFENSE Office of the Secretary Missile Defense Advisory Committee; Notice of Closed Meeting AGENCY: Missile Defense Agency (MDA), Department of Defense. ACTION: Notice of closed meeting... Missile Defense Advisory Committee will take place. DATES: Tuesday, December 13, 2011 through Wednesday...

  11. 76 FR 45783 - Missile Defense Advisory Committee; Notice of Closed Meeting

    Science.gov (United States)

    2011-08-01

    ... DEPARTMENT OF DEFENSE Office of the Secretary Missile Defense Advisory Committee; Notice of Closed Meeting AGENCY: Department of Defense; Missile Defense Agency (MDA). ACTION: Notice of closed meeting... Missile Defense Advisory Committee will take place. DATES: Tuesday, August 16, 2011 through Thursday...

  12. 76 FR 16736 - Closed Meeting of the Missile Defense Advisory Committee

    Science.gov (United States)

    2011-03-25

    ... DEPARTMENT OF DEFENSE Office of the Secretary Closed Meeting of the Missile Defense Advisory Committee AGENCY: Missile Defense Agency (MDA), DoD. ACTION: Notice of closed meeting. SUMMARY: Under the...: Missile Defense Advisory Committee. Dates of Meeting: Thursday, March 24, 2011. Times: 8 a.m. to 5:30 p.m...

  13. Acquisition: Acquisition of Targets at the Missile Defense Agency

    National Research Council Canada - National Science Library

    Ugone, Mary L; Meling, John E; James, Harold C; Haynes, Christine L; Heller, Brad M; Pomietto, Kenneth M; Bobbio, Jaime; Chang, Bill; Pugh, Jacqueline

    2005-01-01

    Who Should Read This Report and Why? Missile Defense Agency program managers who are responsible for the acquisition and management of targets used to test the Ballistic Missile Defense System should be interested in this report...

  14. Soviet debate on missile defense

    Energy Technology Data Exchange (ETDEWEB)

    Parrott, B.

    1987-04-01

    Although the Strategic Defense Initiative (SDI) is meant to cope with the danger of a Soviet nuclear attack, the recent US debate over SDI has paid surprisingly little attention to Soviet views of ballistic missile defense. Despite the existence of a substantial body of pertinent scholarship, the debate has failed to take adequate account of major changes in Soviet ballistic missile defense policy since the mid-1960s. It has also neglected the links between current Soviet military policy and broader Soviet political and economic choices. The Soviets regard SDI not as a novel undertaking to reduce the risks of nuclear war but as an extension of the geopolitical competition between the superpowers. This competition has been dominated in the 1980s, in the Soviet view, by sharply increased US assertiveness and the decline of detente. Viewing SDI as a manifestation of these general trends, Soviet decision makers find the prospect of an unregulated race in ballistic missile defenses and military space technologies deeply unsettling. The deterioration of superpower relations has raised serious doubts in Moscow about the wisdom of Soviet external policy during the 1970s and has provoked sharp internal differences over policy toward the US. Already highly suspicious of the Reagan administration, the elite is united by a general conviction that SDI is an American gambit that may ultimately undercut past Soviet strategic gains and pose a grave new threat to Soviet security. 14 references.

  15. The US-Russia missile defense dialogue as a factor of the Russian defense policy

    OpenAIRE

    Dmitry Suslov

    2013-01-01

    To a big extent the Russian defense policy and, as a consequence, development of the Russian defense industrial complex, is determined by the prospects of the US missile defense policy and fate of the US-Russia negotiations in this area. As a cooperative solution seems improbable in the observable future, Russia plans to develop certain response measures of military nature, including creation of a new heavy ICBM, and to create its own missile defense by 2015. However, this policy does not see...

  16. Information Management Principles Applied to the Ballistic Missile Defense System

    Science.gov (United States)

    2007-03-01

    of a BMDS. From this, the Army produced the Nike -Zeus system comprised of four radars, the Zeus missile, and a computer fire control system (General...made the Nike -Zeus our first National Missile Defense (NMD) system named Sentinel. The architecture was to cover 14 locations, 10 of which were...1999). Additionally, there are cultural impacts (Gordon & Gordon, 1999). A company choosing an Apple OS may have to wage a big fight against the

  17. Study on combat effectiveness of air defense missile weapon system based on queuing theory

    Science.gov (United States)

    Zhao, Z. Q.; Hao, J. X.; Li, L. J.

    2017-01-01

    Queuing Theory is a method to analyze the combat effectiveness of air defense missile weapon system. The model of service probability based on the queuing theory was constructed, and applied to analyzing the combat effectiveness of "Sidewinder" and "Tor-M1" air defense missile weapon system. Finally aimed at different targets densities, the combat effectiveness of different combat units of two types' defense missile weapon system is calculated. This method can be used to analyze the usefulness of air defense missile weapon system.

  18. The National Research Council study: "Making sense of ballistic missile defense"

    Science.gov (United States)

    Wilkening, Dean A.

    2014-05-01

    This chapter explains and summarizes the main findings of a recent National Research Council study entitled Making Sense of Ballistic Missile Defense: An Assessment of Concepts and Systems for U.S. Boost-Phase Missile Defense in Comparison to Other Alternatives.

  19. Deploying Missile Defense: Major Operational Challenges

    National Research Council Canada - National Science Library

    Bunn, M

    2004-01-01

    By October 2004, the United States will have begun initial deployment of a missile defense capability albeit a modest, limited, and not completely proven one to defend the homeland against a limited...

  20. The Development of the US National Missile Defense and its Impact on the International Security

    Directory of Open Access Journals (Sweden)

    J. Yu. Parshkova

    2015-01-01

    Full Text Available The article reflects the US officials' point of view on the development of its national missile defense. The major threat to international security is the proliferation of ballistic missiles and weapons of mass destruction. The United States and the former Soviet Union made huge efforts to reduce and limit offensive arms. However, presently the proliferation of ballistic missiles spreads all over the world, especially in the Middle East, because of the ballistic missile technology falling into the hands of hostile non-state groups. Missile defenses can provide a permanent presence in a region and discourage adversaries from believing they can use ballistic missiles to coerce or intimidate the U.S. or its allies. With the possible attack regional missile defense systems will be promptly mobilized to enhance an effective deterrent. The ultimate goal of such large-scale missile defense deployment is to convince the adversaries that the use of ballistic missiles is useless in military terms and that any attack on the United States and its allies is doomed to failure. The United States has missile defense cooperative programs with a number of allies, including United Kingdom, Japan, Australia, Israel, Denmark, Germany, Netherlands, Czech Republic, Poland, Italy and many others. The Missile Defense Agency also actively participates in NATO activities to maximize opportunities to develop an integrated NATO ballistic missile defense capability. The initiative of the development of US BMD naturally belongs to the United States. That country has enormous technological, financial, economic, military and institutional capabilities, exceeding by far those of the other NATO members combined.

  1. NATO and U.S. Ballistic Missile Defense Programs: Divergent or Convergent Paths?

    National Research Council Canada - National Science Library

    Toms, Kevin E

    2008-01-01

    ...) information network to support the Theater Missile Defense (TMD) capabilities of specific Allies for the protection of forward deployed troops, and studies of the feasibility and political-military implications of Ballistic Missile Defense (BMD...

  2. 76 FR 14589 - Defense Federal Acquisition Regulation Supplement; Repeal of Restriction on Ballistic Missile...

    Science.gov (United States)

    2011-03-17

    ...-AH18 Defense Federal Acquisition Regulation Supplement; Repeal of Restriction on Ballistic Missile...). Section 222 repeals the restriction on purchase of Ballistic Missile Defense research, development, test... Ballistic Missile Defense research, development, test, and evaluation that was required by section 222 of...

  3. Whither Ballistic Missile Defense?

    Science.gov (United States)

    1992-11-30

    important that technology today is placing enormous power in the many camps-not only information that enables timely decision-making, but also the...WHITHER BALLISTIC MISSILE DEFENSE? BY AMBASSADOR HENRY F. COOPER NOVEMBER 30,1992 TECHNICAL MARKETING SOCIETY OF AMERICA WASHINGTON, DC...Conference on Technical Marketing 2000: Opportunities and Strategies for a Changing World) I intend to discuss the prospects for SDI in a changing

  4. Extending U.S. Theater Missile Defense to Northeast Asia: Ramifications for Regional Security

    National Research Council Canada - National Science Library

    Attenweiler, Steven

    2001-01-01

    The absence of a formidable U.S. and allied Theater Missile Defense (TMD) capability in the East Asian region has encouraged a build-up in offensive missile capability on the part of the People's Republic of China (PRC...

  5. Integrating Technologies to Protect the Home Front against Ballistic Threats and Cruise Missiles

    OpenAIRE

    Yossi Arazi; Gal Perel

    2013-01-01

    This article discusses active protection in response to the rocket threat to Israel’s home front. The defense establishment anticipates that in an allout war, the home front would be attacked for about thirty days, and that every day there would be about one thousand rocket and missile hits that would cause thousands of casualties as well as damage to infrastructures and strategic sites. Israel has an active protection system with five layers of interceptor missiles, and in cooperation with t...

  6. Development of System Architecture to Investigate the Impact of Integrated Air and Missile Defense in a Distributed Lethality Environment

    Science.gov (United States)

    2017-12-01

    SYSTEM ARCHITECTURE TO INVESTIGATE THE IMPACT OF INTEGRATED AIR AND MISSILE DEFENSE IN A DISTRIBUTED LETHALITY ENVIRONMENT by Justin K. Davis...TO INVESTIGATE THE IMPACT OF INTEGRATED AIR AND MISSILE DEFENSE IN A DISTRIBUTED LETHALITY ENVIRONMENT 5. FUNDING NUMBERS 6. AUTHOR(S) Justin K...ARCHITECTURE TO INVESTIGATE THE IMPACT OF INTEGRATED AIR AND MISSILE DEFENSE IN A DISTRIBUTED LETHALITY ENVIRONMENT Justin K. Davis Lieutenant

  7. Ballistic Missile Defense and ABM Treaty Limitations

    National Research Council Canada - National Science Library

    Robinson, Brian

    1998-01-01

    The U.S. must critically evaluate our current ballistic missile defense (BMD) strategy. In today's geostrategic context, is it sound strategy to continue to impose 1972 ABM Treaty restrictions on BMD systems development...

  8. 48 CFR 225.7016 - Restriction on Ballistic Missile Defense research, development, test, and evaluation.

    Science.gov (United States)

    2010-10-01

    ... Missile Defense research, development, test, and evaluation. 225.7016 Section 225.7016 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS... Acquisition 225.7016 Restriction on Ballistic Missile Defense research, development, test, and evaluation. [68...

  9. 76 FR 4322 - Availability of the Fiscal Year 2009 Missile Defense Agency Services Contracts Inventory Pursuant...

    Science.gov (United States)

    2011-01-25

    ... DEPARTMENT OF DEFENSE Office of the Secretary Availability of the Fiscal Year 2009 Missile Defense... Act AGENCY: Missile Defense Agency (MDA), DoD. ACTION: Notice of availability. SUMMARY: In accordance... for Fiscal Year 2008 (NDAA 08) Section 807, the Director of the Missile Defense Agency and the Office...

  10. Ballistic Missile Defense: National Security and the High Frontier of Space.

    Science.gov (United States)

    Adragna, Steven P.

    1985-01-01

    Ballistic missile defense is discussed, and the rationale behind the proposal to place defensive weapons in space is examined. Strategic defense is a national security, political, and moral imperative. (RM)

  11. Report of the Defense Science Board/Defense Policy Board Task Force On Theater Missile Defense

    National Research Council Canada - National Science Library

    1996-01-01

    ... also tackled the controversial subject of the ABM Treaty and its effect on theater missile defenses Subsequent to its interim report, which expressed strong concerns about the demarcation path the US...

  12. Veiled Normalization: The Implications of Japanese Missile Defense

    National Research Council Canada - National Science Library

    Clarke, Timothy L

    2008-01-01

    Japan's development of a missile defense system has been accompanied by the acquisition of potentially offensive military assets, an increased command and control capability, significant restructuring...

  13. Missile Defense: LBJ's Bid To Curb Arms Race Gains Support.

    Science.gov (United States)

    Carter, L J

    1967-04-14

    In the article of 31 March on antiballistic missile defense, the last sentence of paragraph 2, p. 1654, should read: "Manpower for producing . . . but the outer limit would be about 200,000, or half the number of contractor employees and civil servants working for NASA at the peak of the Apollo program."

  14. By Land or By Sea: An Analysis of National Missile Defense Options

    National Research Council Canada - National Science Library

    Altman, Bern J

    2000-01-01

    In conformance with the National Missile Defense (NMD) Act of 1999, the United States is pursuing the path to fielding a system capable of providing protection for all of the United States against a limited ballistic missile attack...

  15. Defense Strategy of Aircraft Confronted with IR Guided Missile

    Directory of Open Access Journals (Sweden)

    Hesong Huang

    2017-01-01

    Full Text Available Surface-type infrared (IR decoy can simulate the IR characteristics of the target aircraft, which is one of the most effective equipment to confront IR guided missile. In the air combat, the IR guided missile poses a serious threat to the aircraft when it comes from the front of target aircraft. In this paper, firstly, the model of aircraft and surface-type IR decoy is established. To ensure their authenticity, the aircraft maneuver and radiation models based on real data of flight and exhaust system radiation in the state of different heights and different speeds are established. Secondly, the most effective avoidance maneuver is simulated when the missile comes from the front of the target aircraft. Lastly, combining maneuver with decoys, the best defense strategy is analysed when the missile comes from the front of aircraft. The result of simulation, which is authentic, is propitious to avoid the missile and improve the survivability of aircraft.

  16. THE DEVELOPMENT OF AUTOMATION MANAGEMENT TOOLS BY THE DIVISIONS OF TACTICAL MISSILE DEFENSE

    Directory of Open Access Journals (Sweden)

    O. V. Voronin

    2017-01-01

    Full Text Available The article summarizes the basic directions of automation for planning and management of combat by the divisions of tactical missile defense. The article focuses on the problem of the automated choice of rational option for combat order and fire control carried out by the divisions of tactical missile defense during operation.

  17. Missile proliferation and missile defense

    International Nuclear Information System (INIS)

    Zarif, M. Javad

    2002-01-01

    The global security environment is becoming increasingly volatile and dangerous. A new arms race is looming in the horizon ... [Missiles have] become the strong weapon of the poor and the discriminated against who find themselves vulnerable to outside threat. They believe missiles may prove instrumental in deterring the enemy from beginning a full scale war ... the engagement of all states at the United Nations in the issue of missiles, through the panel of governmental experts, and the new idea of exploring the subject in the Conference on Disarmament do provide a dim light at the end of the tunnel. ... Efforts at non-proliferation of missiles are more likely to succeed when viewed as an integral part of a global and comprehensive negotiation and progress in other areas of disarmament. (author)

  18. Ballistic Missile Defense: New Plans, Old Challenges

    Directory of Open Access Journals (Sweden)

    Elizabeth Zolotukhina

    2010-01-01

    Full Text Available On September 17, 2009—the 70th anniversary of the Soviet invasion of Poland in 1939 that marked the beginning of World War II—the Obama Administration announced its intention to shelve plans for the U.S. Ballistic Missile Defense (BMD that had been developed under former President George W. Bush. Pointing to a new intelligence assessment, President Obama argued that his predecessor's plan to deploy an X-band radar station outside of Prague, Czech Republic, and 10 two-stage interceptor missiles in Poland would not adequately protect America and its European allies from the Iranian threat and reiterated his opposition to utilizing unproven technology in any European BMD architecture.

  19. The Evolution of Missile Defense Plan from Bush to Obama. Implications for the National Security of Romania

    Directory of Open Access Journals (Sweden)

    Ruxandra-Laura BOSILCA

    2012-06-01

    Full Text Available In 2011 Romania officially became part of the Obama administration’s missile defense system in Europe which has significantly changed the strategic military relations both in Europe and worldwide. The Bush approach has been revised and progress in several sections has been achieved, both strategically and technically. For Romania, the participation in the missile defence plan, ensures more solid security guarantees, especially in an unpredictable and risk-prone international environment where the U.S. reconsiders its presence in Europe under the pressure of the economic crisis and of a relative decline in power; it has also become a more visible actor – alongside Bulgaria – which were initially excluded by the Bush missile defence plan. This paper’s purpose is to review the main evolutions of the missile defense plan from the Bush to the Obama administration and to outline its implications on the national security of Romania.

  20. Acquisition: Acquisition of Targets at the Missile Defense Agency

    National Research Council Canada - National Science Library

    Ugone, Mary L; Meling, John E; James, Harold C; Haynes, Christine L; Heller, Brad M; Pomietto, Kenneth M; Bobbio, Jaime; Chang, Bill; Pugh, Jacqueline

    2005-01-01

    .... This audit was performed in response to allegations made to the DoD Hotline in March 2003. This report addresses 10 allegations about the effectiveness of the process that the Missile Defense Agency used to manage and acquire targets...

  1. Missile Defense Attack Operations (Joint Force Quartery, Winter 2000-2001)

    National Research Council Canada - National Science Library

    Watanabe, Nathan

    2001-01-01

    ...- 01.5, Doctrine for Joint Theater Missile Defense, often invokes the term integrate. Although the services are making progress in vertical integration on all levels, little has been done to harmonize efforts horizontally...

  2. The art and science of missile defense sensor design

    Science.gov (United States)

    McComas, Brian K.

    2014-06-01

    A Missile Defense Sensor is a complex optical system, which sits idle for long periods of time, must work with little or no on-­board calibration, be used to find and discriminate targets, and guide the kinetic warhead to the target within minutes of launch. A short overview of the Missile Defense problem will be discussed here, as well as, the top-level performance drivers, like Noise Equivalent Irradiance (NEI), Acquisition Range, and Dynamic Range. These top-level parameters influence the choice of optical system, mechanical system, focal plane array (FPA), Read Out Integrated Circuit (ROIC), and cryogenic system. This paper will not only discuss the physics behind the performance of the sensor, but it will also discuss the "art" of optimizing the performance of the sensor given the top level performance parameters. Balancing the sensor sub-­systems is key to the sensor's performance in these highly stressful missions. Top-­level performance requirements impact the choice of lower level hardware and requirements. The flow down of requirements to the lower level hardware will be discussed. This flow down directly impacts the FPA, where careful selection of the detector is required. The flow down also influences the ROIC and cooling requirements. The key physics behind the detector and cryogenic system interactions will be discussed, along with the balancing of subsystem performance. Finally, the overall system balance and optimization will be discussed in the context of missile defense sensors and expected performance of the overall kinetic warhead.

  3. Study on the Mission, Roles, and Structure of the Missile Defense Agency (MDA)

    National Research Council Canada - National Science Library

    Welch, Larry D; Briggs, David L; Bleach, R. D; Canavan, G. H; Clark-Sestak, S. L; Constantine, R. W; Cook, C. W; Fries, M. S; Frost, D. E; Graham, D. R; Keane, D. J; Kramer, S. D; Major, P. L; Primmerman, C. A; Ruddy, J. M; Schneiter, G. R; Seng, J. M; Stein, R. M; Weiner, S. D; Williams, J. D

    2008-01-01

    ...) was tasked by the Department of Defense to carry out an independent study to examine and make recommendations with respect to the long-term missions, roles, and structure of the Missile Defense Agency (MDA...

  4. Strategic nuclear policy and ballistic missile defense

    International Nuclear Information System (INIS)

    1981-01-01

    The article explains the problems of the antirockets (ABM) as they were part of the presentation Salt I 1972. It is a translation from the English of a publication of the Foreign Affairs Research Institute in London. A topical analysis of the strategic nuclear policy of the two superpowers and their attitudes in the question of ballistic missile defense are given by means of two monographies. (orig./HSCH) [de

  5. China and ballistic missile defense: 1955 to 2002 and beyond

    Energy Technology Data Exchange (ETDEWEB)

    Brad, Roberts

    2004-07-01

    China's opposition to U.S. ballistic missile defense was forcefully articulated officially and unofficially between 1991 and 2001. Vociferous opposition gave way to near silence following U.S. ABM Treaty withdrawal, raising a question about precisely whether and how China will respond to future U.S. deployments in both the political and military-operational realms. To gauge likely future responses, it is useful to put the experience of the 1991-2001 period into historical context. China's attitudes toward BMD have passed through a series of distinct phases since the beginning of the nuclear era, as China has been concerned alternately with the problems of strategic defense by both the Soviet Union and United States (and others) around its periphery. Throughout this era it has also pursued its own strategic defense capabilities. There are important elements of continuity in China's attitudes concerns about the viability of its own force and about strategic stability. These suggest the likelihood of significant responses to U.S. BMD even in the absence of sharp rhetoric. (author)

  6. China and ballistic missile defense: 1955 to 2002 and beyond

    International Nuclear Information System (INIS)

    Brad, Roberts

    2004-01-01

    China's opposition to U.S. ballistic missile defense was forcefully articulated officially and unofficially between 1991 and 2001. Vociferous opposition gave way to near silence following U.S. ABM Treaty withdrawal, raising a question about precisely whether and how China will respond to future U.S. deployments in both the political and military-operational realms. To gauge likely future responses, it is useful to put the experience of the 1991-2001 period into historical context. China's attitudes toward BMD have passed through a series of distinct phases since the beginning of the nuclear era, as China has been concerned alternately with the problems of strategic defense by both the Soviet Union and United States (and others) around its periphery. Throughout this era it has also pursued its own strategic defense capabilities. There are important elements of continuity in China's attitudes concerns about the viability of its own force and about strategic stability. These suggest the likelihood of significant responses to U.S. BMD even in the absence of sharp rhetoric. (author)

  7. The Threat from European Missile Defence System to Russian National Security

    Directory of Open Access Journals (Sweden)

    Alexey I. Podberezkin

    2014-01-01

    Full Text Available The article analyses the political and military aspects of progress in the dialogue between Russia and the U.S./NATO on cooperation in missile defense; investigates the past experiences and current state of cooperation between Russia and the Alliance on missile defense issues; examines the technical features of American missile defence systems today; finds a solution to question whether or not the European Missile Defence Program actually threatens Russia's nuclear deterrent and strategic stability in general; identifies both potential benefits and possible losses for Russia stemming from the development of cooperation with the United States and NATO in countering ballistic missile threats, or from refusal to have such cooperation. Evidently, the initiative of creation of a missile defense in Europe surely belongs to the USA. Washington has enormous technological, financial, economic, military and institutional capabilities in the field of a missile defense, exceeding by far other NATO member-states. In February 2010, the President of the United States B. Obama adopted a project "European Phased Adaptive Approach" (EPAA as an alternative to G. Bush's global strategic missile defense plan. The first two stages of the Phased Adaptive Approach are focused on creating a system capable of intercepting small, medium and intermediate-range ballistic missiles. The possibility of intercepting long-range missiles is postponed to the third (2018 and forth phases (2020. Moscow finds especially troublesome the third and the fourth phases of Washington's project of creating a European segment of the global antiballistic missile system, considering prospective capabilities of the U.S. interceptor missiles 61 and the envisioned areas of their deployment. The U.S. counter-evidence is that phase four interceptors do not exist yet. Russia insists on getting the political and legal guarantees from the U.S. and NATO that their missile defense systems will not slash

  8. Formal Specification and Run-time Monitoring Within the Ballistic Missile Defense Project

    National Research Council Canada - National Science Library

    Caffall, Dale S; Cook, Thomas; Drusinsky, Doron; Michael, James B; Shing, Man-Tak; Sklavounos, Nicholas

    2005-01-01

    .... Ballistic Missile Defense Advanced Battle Manager (ABM) project in an effort that is amongst the most comprehensive application of formal methods to a large-scale safety-critical software application ever reported...

  9. Regional Joint-Integrated Air and Missile Defense (RF-IAMD): An Operational Level Integrated Air and Missile Defense (IAMD) Command and Control (C2) Organization

    Science.gov (United States)

    2015-05-15

    Accessed April 26, 2015, http://www.state.gov/t/ avc /rls/2014/226073.html 24 Pacific Air Forces, PACAF establishes Pacific IAMD Center, Accessed April...U.S. Department of State. Gulf Cooperation Council and Ballistic Missile Defense. Accessed April 26, 2015. http://www.state.gov/t/ avc /rls/2014

  10. Ballistic Missile Defense in the European Theater: Political, Military and Technical Considerations

    National Research Council Canada - National Science Library

    Terstegge, Stephen D

    2007-01-01

    ... that threatens the homeland of the United States. Therefore, the United States faces the complex security challenge of emplacing ballistic missile defense assets on European soil in the very near-term to mitigate this threat...

  11. Iranian Ballistic Missile Threat and a Phased, Adaptive Approach for Missile Defense in Europe: Perceptions, Policies and Scenarios

    Science.gov (United States)

    2010-09-15

    vii ACRONYMS AA Aegis Ashore ABL Airborne Laser ABM Anti-Ballistic Missile ADCF Air Defense Command Frigates AEOI ...in September 2002 at the IAEA’s General Conference in Vienna, Iran’s Vice President and President of the Atomic Energy Organization of Iran ( AEOI

  12. Ship Anti Ballistic Missile Response (SABR)

    OpenAIRE

    Johnson, Allen P.; Breeden, Bryan; Duff, Willard Earl; Fishcer, Paul F.; Hornback, Nathan; Leiker, David C.; Carlisle, Parker; Diersing, Michael; Devlin, Ryan; Glenn, Christopher; Hoffmeister, Chris; Chong, Tay Boon; Sing, Phang Nyit; Meng, Low Wee; Meng, Fann Chee

    2006-01-01

    Includes supplementary material. Based on public law and Presidential mandate, ballistic missile defense development is a front-burner issue for homeland defense and the defense of U.S. and coalition forces abroad. Spearheaded by the Missile Defense Agency, an integrated ballistic missile defense system was initiated to create a layered defense composed of land-, air-, sea-, and space-based assets. The Ship Anti-Ballistic Response (SABR) Project is a systems engineering approach t...

  13. Can patriotism justify killing in defense of one’s country?

    Directory of Open Access Journals (Sweden)

    Pavković Aleksandar

    2007-01-01

    Full Text Available Cosmopolitan liberals would be ready to fight - and to kill and be killed for the sake of restoring international justice or for the abolition of profoundly unjust political institutions. Patriots are ready to do the same for their own country. Sometimes the cosmopolitan liberals and patriots would fight on the same side and sometimes on the opposite sides of the conflict. Thus the former would join the latter in the defense of Serbia against Austria-Hungary (in 1914 but would oppose the white Southerner patriots in the American Civil War (in 1861. In this paper I argue that fighting and killing for one’s country is, in both of those cases, different from the defense of one’s own life and the lives of those who cannot defend themselves. Killing for one’s country is killing in order to fulfill a particular political preference. The same is the case with fighting for the abolition of a profoundly unjust political institution. It is not amoral or immoral to refuse to kill for any one of these two political preferences because there is no reason to believe that either political preference trumps our moral constraints against killing.

  14. Probabilistic assessment of tornado-borne missile speeds. Final report

    International Nuclear Information System (INIS)

    Simiu, E.; Cordes, M.R.

    1980-09-01

    A procedure was developed for estimating speeds with which postulated missiles hit any given set of targets in a nuclear power plant or similar installation. Hit speeds corresponding to probabilities of occurrence of .0000001 were calculated for a given nuclear power plant under various assumptions concerning the magnitude of the force opposing missile take-off, direction of tornado axis of translation, number and location of missiles, and size of target area. The results of the calculations are shown to depend upon the parameters: CDA/m, where CD = drag coefficient, A = projected area, m = mass of missiles, and the ratio, k, between the minimum aerodynamic force required to cause missile take-off, and the weight of the missile

  15. The National Guard Ballistic Missile Defense Mission minutemen at the Orgital Plane

    OpenAIRE

    Trenary, Ralph Hiram

    2004-01-01

    Approved for public release; distribution is unlimited This thesis examines the decision to assign the Ballistic Missile Defense mission to units of the Colorado and Alaska National Guard. The history of the Nike Ajax, Nike Hercules, Sentinel and Safeguard programs are examined to identify the origins of support for this decision. First-hand sources provide evidence that the National Guard performance in the Nike air defense program is a record of parity and some superiority to equivalent ...

  16. Strategy alternatives for homeland air and cruise missile defense.

    Science.gov (United States)

    Murphy, Eric M; Payne, Michael D; Vanderwoude, Glenn W

    2010-10-01

    Air and cruise missile defense of the U.S. homeland is characterized by a requirement to protect a large number of critical assets nonuniformly dispersed over a vast area with relatively few defensive systems. In this article, we explore strategy alternatives to make the best use of existing defense resources and suggest this approach as a means of reducing risk while mitigating the cost of developing and acquiring new systems. We frame the issue as an attacker-defender problem with simultaneous moves. First, we outline and examine the relatively simple problem of defending comparatively few locations with two surveillance systems. Second, we present our analysis and findings for a more realistic scenario that includes a representative list of U.S. critical assets. Third, we investigate sensitivity to defensive strategic choices in the more realistic scenario. As part of this investigation, we describe two complementary computational methods that, under certain circumstances, allow one to reduce large computational problems to a more manageable size. Finally, we demonstrate that strategic choices can be an important supplement to material solutions and can, in some cases, be a more cost-effective alternative. © 2010 Society for Risk Analysis.

  17. Validation of the Comprehensive Assessment of Defense Style (CADS): mothers' and children's responses to the stresses of missile attacks.

    Science.gov (United States)

    Wolmer, L; Laor, N; Cicchetti, D V

    2001-06-01

    This study furthers the validation of the Comprehensive Assessment of Defense Style (CADS) as a measure of children's defensive behavior. Participants were 81 mothers who assessed the defense style (CADS) of their 8- to 10-year-old children, as well as their own defense style and level of object relations. Five years earlier, the mothers had rated their children's symptom level and personality after the missile attacks during the Gulf War. The original factor structure of the CADS was replicated for the most part. Self-oriented and other-oriented defenses were related to the children's early personality and symptomatic reaction, as well as to their mother's defense style and level of object relations. The CADS factors correlated with the defenses of the Defense Mechanisms Manual. The results provide further validation of the CADS and suggest possible areas of implementation, such as longitudinal examination of defenses, psychopathology screening, and therapeutic improvement.

  18. A Potent Vector: Assessing Chinese Cruise Missile Developments

    Science.gov (United States)

    2014-01-01

    likelihood that they will successfully penetrate defenses.1 Employed in salvos, perhaps in tandem with ballistic missiles, cruise missiles could...series cruise missiles for export.4 Finally, for three decades China has marketed a wide range of indig- enously produced cruise missiles (and other...distances and thus more vulnerable to at- tacks from advanced air defense systems, such as Aegis. Both missiles execute sea- skimming attacks at an

  19. Siting Report for Theater Missile Defense Mid-Range Test Launch Complex at Ft. Wingate Depot Activity, NM: Based on Sit Survey, 14-18 February 1994

    National Research Council Canada - National Science Library

    1994-01-01

    This study is provided to assess the capability of Ft. Wingate Depot Activity to act as a Ballistic Missile Defense Test Support Complex for the launch of target missiles toward White Sands Missile Range...

  20. MOQPSO-D/S for Air and Missile Defense WTA Problem under Uncertainty

    Directory of Open Access Journals (Sweden)

    Hao Xu

    2017-01-01

    Full Text Available Aiming at the shortcomings of single objective optimization for solving weapon target assignment (WTA and the existing multiobjective optimization based WTA method having problems being applied in air and missile defense combat under uncertainty, a fuzzy multiobjective programming based WTA method was proposed to enhance the adaptability of WTA decision to the changes of battlefield situation. Firstly, a multiobjective quantum-behaved particle swarm optimization with double/single-well (MOQPSO-D/S algorithm was proposed by adopting the double/single-well based position update method, the hybrid random mutation method, and the two-stage based guider particles selection method. Secondly, a fuzzy multiobjective programming WTA model was constructed with consideration of air and missile defense combat’s characteristics. And, the uncertain WTA model was equivalently clarified based on the necessity degree principle of uncertainty theory. Thirdly, with particles encoding and illegal particles adjusting, the MOQPSO-D/S algorithm was adopted to solve the fuzzy multiobjective programming based WTA model. Finally, example simulation was conducted, and the result shows that the WTA model constructed is rational and MOQPSO-D/S algorithm is efficient.

  1. Golf Balls, Boomerangs and Asteroids The Impact of Missiles on Society

    CERN Document Server

    Kaye, Brian H

    1996-01-01

    Exciting reading for anyone with a curious mind!. 'Walking one day by a golf course in Wisconsin, I was startled to hear a sharp bang as a golf ball narrowly missed my head and hit a tree. My companion cheerfully remarked, 'That could have killed you, you know.' I picked up the innocent looking little white ball and looked at it with new respect.'. Prompted by this perilous experience, Brian Kaye has written a delightful and informative book on the design and behavior of different kinds of missiles from golf balls, arrows, and slingshots to comets and rockets to outer space. You'll learn about

  2. Advanced Missile Signature Center

    Data.gov (United States)

    Federal Laboratory Consortium — The Advanced Missile Signature Center (AMSC) is a national facility supporting the Missile Defense Agency (MDA) and other DoD programs and customers with analysis,...

  3. Laser Options for National Missile Defense

    National Research Council Canada - National Science Library

    Leonard, Steven

    1998-01-01

    The Cold War threat that was characterized by a USSR launch of a large number of ballistic missiles towards the United States has been replaced today by an even less stable ballistic missile security environment...

  4. Modeling of Target Tracking System for Homing Missiles and Air Defense Systems

    Directory of Open Access Journals (Sweden)

    Yunes Sh. ALQUDSI

    2018-06-01

    Full Text Available One reason of why the guidance and control systems are imperfect is due to the dynamics of both the tracker and the missile, which appears as an error in the alignment with the LOS and delay in the response of the missile to change its orientation. Other reasons are the bias and disturbances as well as the noise about and within the system such as the thermal noise. This paper deals with the tracking system used in the homing guidance and air defense systems. A realistic model for the tracking system model is developed including the receiver servo dynamics and the possible disturbance and noise that may affect the accuracy of the tracking signals measured by the seeker sensor. Modeling the parameters variability and uncertainty is also examined to determine the robustness margin of the tracking system.

  5. MILITARY RESEARCH: Researchers Target Flaws in Ballistic Missile Defense Plan.

    Science.gov (United States)

    Malakoff, D; Cho, A

    2000-06-16

    More than three dozen scientists journeyed to Washington, D.C., this week to warn lawmakers that a proposed $60 billion U.S. missile defense system, designed to knock incoming warheads out of the sky, is technically flawed because it can't pick out real warheads from decoys. Pentagon officials heatedly deny a new report by one scientist that contractors have rigged trials to hide the problem, although they admit that some tests were simplified to save time. In the wake of these events, a leading Democrat is urging President Bill Clinton to delay a pending decision on building the system.

  6. Time-to-impact estimation in passive missile warning systems

    Science.gov (United States)

    Şahıngıl, Mehmet Cihan

    2017-05-01

    A missile warning system can detect the incoming missile threat(s) and automatically cue the other Electronic Attack (EA) systems in the suit, such as Directed Infrared Counter Measure (DIRCM) system and/or Counter Measure Dispensing System (CMDS). Most missile warning systems are currently based on passive sensor technology operating in either Solar Blind Ultraviolet (SBUV) or Midwave Infrared (MWIR) bands on which there is an intensive emission from the exhaust plume of the threatening missile. Although passive missile warning systems have some clear advantages over pulse-Doppler radar (PDR) based active missile warning systems, they show poorer performance in terms of time-to-impact (TTI) estimation which is critical for optimizing the countermeasures and also "passive kill assessment". In this paper, we consider this problem, namely, TTI estimation from passive measurements and present a TTI estimation scheme which can be used in passive missile warning systems. Our problem formulation is based on Extended Kalman Filter (EKF). The algorithm uses the area parameter of the threat plume which is derived from the used image frame.

  7. Modular Open System Architecture for Reducing Contamination Risk in the Space and Missile Defense Supply Chain

    Science.gov (United States)

    Seasly, Elaine

    2015-01-01

    To combat contamination of physical assets and provide reliable data to decision makers in the space and missile defense community, a modular open system architecture for creation of contamination models and standards is proposed. Predictive tools for quantifying the effects of contamination can be calibrated from NASA data of long-term orbiting assets. This data can then be extrapolated to missile defense predictive models. By utilizing a modular open system architecture, sensitive data can be de-coupled and protected while benefitting from open source data of calibrated models. This system architecture will include modules that will allow the designer to trade the effects of baseline performance against the lifecycle degradation due to contamination while modeling the lifecycle costs of alternative designs. In this way, each member of the supply chain becomes an informed and active participant in managing contamination risk early in the system lifecycle.

  8. Influence of Missile Fusillade Engagement Mode on Operation Efficiency

    Institute of Scientific and Technical Information of China (English)

    BU Xian-jin; REN Yi-guang; SHA Ji-chang

    2008-01-01

    Shoot efficiency is one of the most important evaluation indexes of the operation efficiency of weapon system. In this paper, based on definitions of the probability and the expected number of missed attacking missiles, the expected numbers of anti-missiles and attacking missiles hit by single anti-missile, fusillade mechanism of multi-missile is analyzed systematically. The weapon operation efficiency in various engagement patterns is also studied. The results show that double missiles fusillade is the most feasible manner for increasing the weapon operation efficiency.

  9. An anthology: Rationale for a US ballistic missile defense (1969 - 1984)

    Science.gov (United States)

    Tircuit, E. C.

    1985-04-01

    This anthology is a selection and short synopsis of representative articles on the rationale for a US ballistic missile defense (BMD). Unclassified articles and documents were reviewed and analyzed to identify and include nine representative articles in the anthology. The anthology reduces the search for quality material on the subject and documents the fundamental rationale for a BMD. The author concluded that the fundamental rationale for a US BMD is to deter nuclear war. In addition, specific rationale for a US BMD is provided in the anthology. Finally, an extensive bibliography is included in the anthology to enhance further research on the subject.

  10. Embedded Systems - Missile Detection/Interception

    Directory of Open Access Journals (Sweden)

    Luis Cintron

    2010-01-01

    Full Text Available Missile defense systems are often related to major military resources aimed at shielding a specific region from incoming attacks. They are intended to detect, track, intercept, and destruct incoming enemy missiles. These systems vary in cost, efficiency, dependability, and technology. In present times, the possession of these types of systems is associated with large capacity military countries. Demonstrated here are the mathematical techniques behind missile systems which calculate trajectories of incoming missiles and potential intercept positions after initial missile detection. This procedure involved the use of vector-valued functions, systems of equations, and knowledge of projectile motion concepts.

  11. Planetary Defense From Space: Part 2 (Simple) Asteroid Deflection Law

    Science.gov (United States)

    Maccone, Claudio

    2006-06-01

    A system of two space bases housing missiles for an efficient Planetary Defense of the Earth from asteroids and comets was firstly proposed by this author in 2002. It was then shown that the five Lagrangian points of the Earth Moon system lead naturally to only two unmistakable locations of these two space bases within the sphere of influence of the Earth. These locations are the two Lagrangian points L1 (in between the Earth and the Moon) and L3 (in the direction opposite to the Moon from the Earth). In fact, placing missiles based at L1 and L3 would enable the missiles to deflect the trajectory of incoming asteroids by hitting them orthogonally to their impact trajectory toward the Earth, thus maximizing the deflection at best. It was also shown that confocal conics are the only class of missile trajectories fulfilling this “best orthogonal deflection” requirement. The mathematical theory developed by the author in the years 2002 2004 was just the beginning of a more expanded research program about the Planetary Defense. In fact, while those papers developed the formal Keplerian theory of the Optimal Planetary Defense achievable from the Earth Moon Lagrangian points L1 and L3, this paper is devoted to the proof of a simple “(small) asteroid deflection law” relating directly the following variables to each other:the speed of the arriving asteroid with respect to the Earth (known from the astrometric observations);the asteroid's size and density (also supposed to be known from astronomical observations of various types);the “security radius” of the Earth, that is, the minimal sphere around the Earth outside which we must force the asteroid to fly if we want to be safe on Earth. Typically, we assume the security radius to equal about 10,000 km from the Earth center, but this number might be changed by more refined analyses, especially in the case of “rubble pile” asteroids;the distance from the Earth of the two Lagrangian points L1 and L3 where the

  12. Civilian casualties of Iraqi ballistic missile attack to

    Directory of Open Access Journals (Sweden)

    Khaji Ali

    2012-06-01

    Full Text Available 【Abstract】Objective: To determine the pattern of causalities of Iraqi ballistic missile attacks on Tehran, the capital of Iran, during Iraq-Iran war. Methods: Data were extracted from the Army Staff Headquarters based on daily reports of Iranian army units during the war. Results: During 52 days, Tehran was stroked by 118 Al-Hussein missiles (a modified version of Scud missile. Eighty-six missiles landed in populated areas. During Iraqi missile attacks, 422 civilians died and 1 579 injured (4.9 deaths and 18.3 injuries per missile. During 52 days, 8.1 of the civilians died and 30.4 injured daily. Of the cases that died, 101 persons (24% were excluded due to the lack of information. Among the remainders, 179 (55.8% were male and 142 (44.2% were female. The mean age of the victims was 25.3 years±19.9 years. Our results show that the high accuracy of modified Scud missiles landed in crowded ar-eas is the major cause of high mortality in Tehran. The pres-ence of suitable warning system and shelters could reduce civilian casualties. Conclusion: The awareness and readiness of civilian defense forces, rescue services and all medical facilities for dealing with mass casualties caused by ballistic missile at-tacks are necessary. Key words: Mortality; War; Mass casualty incidents; Wounds and injuries

  13. Navy Shipboard Lasers for Surface, Air, and Missile Defense: Background and Issues for Congress

    Science.gov (United States)

    2013-06-27

    fiber SSL effort is called the Tactical Laser System ( TLS ). Among DOD’s multiple efforts to develop slab SSLs for military use was the Maritime Laser...Missile Defense Congressional Research Service 11 Tactical Laser System Another Navy fiber SSL effort is the Tactical Laser System ( TLS )—a laser...and DOD have conducted development work on three principal types of lasers for potential use on Navy surface ships—fiber solid state lasers ( SSLs

  14. Design trade-offs for homing missiles

    Science.gov (United States)

    Spencer, Allen; Moore, William

    1992-05-01

    Major design considerations, trade-offs and technology issues for future hypervelocity, anti-missile interceptors are presented in an overview format. Two classes of interceptors are considered: a low altitude interceptor using an active radar seeker for defense against tactical ballistic missiles (TBMs) and a higher altitude interceptor using a passive infra-red seeker for defense against ICBMs. Considerations are presented in the areas of mission requirements, seeker selection, aerodynamic and aerothermal environments, control systems, and guidance performance.

  15. NPS Faculty, Students Develop Strategic Missile Defense Tool

    OpenAIRE

    Dionne, Patrick

    2017-01-01

    News Stories Archive In May 2017, the United States successfully intercepted an intercontinental ballistic missile in the first-ever test of the U.S.'s long-range, anti-missile capabilities. While impactful, it is just th...

  16. Integrated CLOS and PN Guidance for Increased Effectiveness of Surface to Air Missiles

    Directory of Open Access Journals (Sweden)

    Binte Fatima Tuz ZAHRA

    2017-06-01

    Full Text Available In this paper, a novel approach has been presented to integrate command to line-of-sight (CLOS guidance and proportional navigation (PN guidance in order to reduce miss distance and to increase the effectiveness of surface to air missiles. Initially a comparison of command to line-of-sight guidance and proportional navigation has been presented. Miss distance, variation of angle-of-attack, normal and lateral accelerations and error of missile flight path from direct line-of-sight have been used as noteworthy criteria for comparison of the two guidance laws. Following this comparison a new approach has been proposed for determining the most suitable guidance gains in order to minimize miss distance and improve accuracy of the missile in delivering the warhead, while using CLOS guidance. This proposed technique is based on constrained nonlinear minimization to optimize the guidance gains. CLOS guidance has a further limitation of significant increase in normal and lateral acceleration demands during the terminal phase of missile flight. Furthermore, at large elevation angles, the required angle-of-attack during the terminal phase increases beyond design specifications. Subsequently, a missile with optical sensors only and following just the CLOS guidance has less likelihood to hit high speed targets beyond 45º in elevation plane. A novel approach has thus been proposed to overcome such limitations of CLOS-only guidance for surface to air missiles. In this approach, an integrated guidance algorithm has been proposed whereby the initial guidance law during rocket motor burnout phase remains CLOS, whereas immediately after this phase, the guidance law is automatically switched to PN guidance. This integrated approach has not only resulted in slight increase in range of the missile but also has significantly improved its likelihood to hit targets beyond 30 degrees in elevation plane, thus successfully overcoming various limitations of CLOS

  17. How will the Indian military's upgrade and modernization of its ISR, precision strike, and missile defense affect the stability in South Asia?

    OpenAIRE

    Dewan, Jay P.

    2005-01-01

    Approved for public release, distribution is unlimited India has made a concerted effort to upgrade its ISR, precision strike, and missile defense capabilities as it competes with China and Pakistan for regional power. The Phalcon Airborne Warning and Control System, Su-30MKI fighter-bomber aircraft, and S-300PMU surface-to-air missile system are some examples of the new capabilities India is acquiring. I argue that if India continues its military modernization, Pakistan will become more i...

  18. Air defense planning for an area with the use of very short range air defense sets

    Directory of Open Access Journals (Sweden)

    Tadeusz Pietkiewicz

    2017-12-01

    Full Text Available This paper presents a heuristic method of planning the deployment of very short-range anti-air missile and artillery sets (VSHORAD around an area (‘protected area’ in order to protect it. A function dependent on the distance between the earliest feasible points of destroying targets and the centre of the protected area was taken as an objective function. This is a different indicator from those commonly used in the literature, and based on the likelihood of a defense zone penetration by means of an air attack (MAA: the kill probability of the MAA and the probability of area losses. The model constraints resulted directly from the restrictions imposed by real air defense systems and the nature of the area being defended. This paper assumes that the VSHORAD system operates as a part of a general, superordinate air defense command and control system based on the idea of network-centric warfare, which provides the VSHORAD system with a recognized air picture, air defense plans, and combat mission specifications. The presented method has been implemented. The final part of the paper presents the computational results. Keywords: optimal planning, air defense system, area installation protection, deployment of very short range anti-air missile and artillery sets (VSHORAD

  19. MODELING THE FLIGHT TRAJECTORY OF OPERATIONAL-TACTICAL BALLISTIC MISSILES

    Directory of Open Access Journals (Sweden)

    I. V. Filipchenko

    2018-01-01

    Full Text Available The article gives the basic approaches to updating the systems of combat operations modeling in the part of enemy missile attack simulation taking into account the possibility of tactical ballistic missile maneuvering during the flight. The results of simulation of combat tactical missile defense operations are given. 

  20. Multiradar tracking for theater missile defense

    Science.gov (United States)

    Sviestins, Egils

    1995-09-01

    A prototype system for tracking tactical ballistic missiles using multiple radars has been developed. The tracking is based on measurement level fusion (`true' multi-radar) tracking. Strobes from passive sensors can also be used. We describe various features of the system with some emphasis on the filtering technique. This is based on the Interacting Multiple Model framework where the states are Free Flight, Drag, Boost, and Auxiliary. Measurement error modeling includes the signal to noise ratio dependence; outliers and miscorrelations are handled in the same way. The launch point is calculated within one minute from the detection of the missile. The impact point, and its uncertainty region, is calculated continually by extrapolating the track state vector using the equations of planetary motion.

  1. Research on air and missile defense task allocation based on extended contract net protocol

    Science.gov (United States)

    Zhang, Yunzhi; Wang, Gang

    2017-10-01

    Based on the background of air and missile defense distributed element corporative engagement, the interception task allocation problem of multiple weapon units with multiple targets under network condition is analyzed. Firstly, a mathematical model of task allocation is established by combat task decomposition. Secondly, the initialization assignment based on auction contract and the adjustment allocation scheme based on swap contract were introduced to the task allocation. Finally, through the simulation calculation of typical situation, the model can be used to solve the task allocation problem in complex combat environment.

  2. European Missile Defense and Russia

    Science.gov (United States)

    2014-07-01

    Moskovskiy Komsomolets, September 18, 2009. 27. U.S. Department of State website, available from www. state.gov/t/ avc /rls/162447.htm. 28. BBC Monitoring (BBCM...see www.state.gov/t/ avc /c52028.htm and www. slideshare.net/rusemblon/russian-mod-views-on-nato-missile-defence- in-europe, respectively. 67

  3. Department of Defense high power laser program guidance

    Science.gov (United States)

    Muller, Clifford H.

    1994-06-01

    The DoD investment of nominally $200 million per year is focused on four high power laser (HPL) concepts: Space-Based Laser (SBL), a Ballistic Missile Defense Organization effort that addresses boost-phase intercept for Theater Missile Defense and National Missile Defense; Airborne Laser (ABL), an Air Force effort that addresses boost-phase intercept for Theater Missile Defense; Ground-Based Laser (GBL), an Air Force effort addressing space control; and Anti-Ship Missile Defense (ASMD), a Navy effort addressing ship-based defense. Each organization is also supporting technology development with the goal of achieving less expensive, brighter, and lighter high power laser systems. These activities represent the building blocks of the DoD program to exploit the compelling characteristics of the high power laser. Even though DoD's HPL program are focused and moderately strong, additional emphasis in a few technical areas could help reduce risk in these programs. In addition, a number of options are available for continuing to use the High-Energy Laser System Test Facility (HELSTF) at White Sands Missile Range. This report provides a brief overview and guidance for the five efforts which comprise the DoD HPL program (SBL, ABL, GBL, ASMD, HELSTF).

  4. Ballistic Missile Defense System (BMDS)

    Science.gov (United States)

    2015-12-01

    Deliveries: 1 JBMD BLK 04 Computer Program, Peripherals, and SM-3 BLK IA Missiles. Japan 8/13/2004 0 21.3 FMS Case JA-P-BGQ: Proof of Principle (PoP...Estimate Econ Qty Sch Eng Est Oth Spt Total 0.000 -- -- -- -- -- -- -- -- 0.000 An APUC Unit Cost History is not available, since no Initial APUC Estimate

  5. Missile Electro-Optical Countermeasures Simulation Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory comprises several hardware-in-the-loop missile flight simulations designed specifically to evaluate the effectiveness of electro-optical air defense...

  6. Toward a new task assignment and path evolution (TAPE) for missile defense system (MDS) using intelligent adaptive SOM with recurrent neural networks (RNNs).

    Science.gov (United States)

    Wang, Chi-Hsu; Chen, Chun-Yao; Hung, Kun-Neng

    2015-06-01

    In this paper, a new adaptive self-organizing map (SOM) with recurrent neural network (RNN) controller is proposed for task assignment and path evolution of missile defense system (MDS). We address the problem of N agents (defending missiles) and D targets (incoming missiles) in MDS. A new RNN controller is designed to force an agent (or defending missile) toward a target (or incoming missile), and a monitoring controller is also designed to reduce the error between RNN controller and ideal controller. A new SOM with RNN controller is then designed to dispatch agents to their corresponding targets by minimizing total damaging cost. This is actually an important application of the multiagent system. The SOM with RNN controller is the main controller. After task assignment, the weighting factors of our new SOM with RNN controller are activated to dispatch the agents toward their corresponding targets. Using the Lyapunov constraints, the weighting factors for the proposed SOM with RNN controller are updated to guarantee the stability of the path evolution (or planning) system. Excellent simulations are obtained using this new approach for MDS, which show that our RNN has the lowest average miss distance among the several techniques.

  7. Calibration of IR test chambers with the missile defense transfer radiometer

    Science.gov (United States)

    Kaplan, Simon G.; Woods, Solomon I.; Carter, Adriaan C.; Jung, Timothy M.

    2013-05-01

    The Missile Defense Transfer Radiometer (MDXR) is designed to calibrate infrared collimated and flood sources over the fW/cm2 to W/cm2 power range from 3 μm to 28μ m in wavelength. The MDXR operates in three different modes: as a filter radiometer, a Fourier-transform spectrometer (FTS)-based spectroradiometer, and as an absolute cryogenic radiometer (ACR). Since 2010, the MDXR has made measurements of the collimated infrared irradiance at the output port of seven different infrared test chambers at several facilities. We present a selection of results from these calibration efforts compared to signal predictions from the respective chamber models for the three different MDXR calibration modes. We also compare the results to previous measurements made of the same chambers with a legacy transfer radiometer, the NIST BXR. In general, the results are found to agree within their combined uncertainties, with the MDXR having 30 % lower uncertainty and greater spectral coverage.

  8. Comparison of two mathematical models for describing heat-induced cell killing

    International Nuclear Information System (INIS)

    Roti Roti, J.L.; Henle, K.J.

    1980-01-01

    A computer-based minimization algorithm is utilized to obtain the optimum fits of two models to hyperthermic cell killing data. The models chosen are the multitarget, single-hit equation, which is in general use, and the linear-quadratic equation, which has been applied to cell killing by ionizing irradiation but not to heat-induced cell killing. The linear-quadratic equation fits hyperthermic cell killing data as well as the multitarget, single-hit equation. Both parameters of the linear-quadratic equation obey the Arrhenius law, whereas only one of the two parameters of the multitarget, single-hit equation obeys the Arrhenius law. Thus the linear-quadratic function can completely define cell killing as a function of both time and temperature. In addition, the linear-quadratic model will provide a simplified approach to the study of the synergism between heat and X irradiation

  9. Hyper Velocity Missiles For Defence

    Directory of Open Access Journals (Sweden)

    Faqir Minhas

    2005-10-01

    Full Text Available The paper reviews the history of technical development in the field of hypervelocity missiles. It highlights the fact that the development of anti-ballistic systems in USA, Russia, France, UK, Sweden, and Israel is moving toward the final deployment stage; that USA and Israel are trying to sell PAC 2 and Arrow 2 to India; and that India’s Agni and Prithvi missiles have improved their accuracy, with assistance from Russia. Consequently, the paper proposes enhanced effort for development in Pakistan of a basic hypersonic tactical missile, with 300 KM range, 500 KG payload, and multi-rolecapability. The author argues that a system, developed within the country, at the existing or upgraded facilities, will not violate MTCR restrictions, and would greatly enhance the country’s defense capability. Furthermore, it would provide high technology jobs toPakistani citizens. The paper reinforces the idea by suggesting that evolution in the field of aviation and electronics favors the development of ballistic, cruise and guided missile technologies; and that flight time of short and intermediate range missiles is so short that its interception is virtually impossible.

  10. Distributed cooperative guidance for multiple missiles with fixed and switching communication topologies

    Directory of Open Access Journals (Sweden)

    Qilun ZHAO

    2017-08-01

    Full Text Available This study investigates cooperative guidance problems for multiple missiles with fixed and switching directed communication topologies. A two-step guidance strategy is proposed to realize the simultaneous attack. In the first step, a distributed cooperative guidance law is designed using local neighboring information for multiple missiles to achieve consensus on range-to-go and leading angle. The second step begins when the consensus of multiple missiles is realized. During the second step, multiple missiles disconnect from each other and hit the target using the proportional navigation guidance law. First, based on the local neighboring communications, a sufficient condition for multiple missiles to realize simultaneous attack with a fixed communication topology is presented, where the topology is only required to have a directed spanning tree. Then, the results are extended to the case of switching communication topologies. Finally, numerical simulations are provided to validate the theoretical results.

  11. ROMANIA’S PARTICIPATION TO THE AEGIS BALLISTIC MISSILE DEFENSE SYSTEM AS REFLECTED BY ROMANIAN NEWSPAPERS’ EVALUATIVE DISCOURSE

    Directory of Open Access Journals (Sweden)

    Raluca Mihaela LEVONIAN

    2012-01-01

    Full Text Available This study aims to investigate Romanian media discourse on the current standing of the relations between Romania and the United States of America in the military fi eld. The main topic investigated is connected to Romania’s decision to host the land-based component of the Balllistic Missile Defense System on its ground, an event which attracted signifi cant media coverage during the year 2011. The corpus analyzed consisted of 37 news and opinion items and reports published on the site of three Romanian newspapers. The main research questions were to assess whether the evaluations of this event were positive or negative, who were the actors issuing these statements and what objects were discussed in association to this event. The results showed that positive evaluations were more common than negative evaluations and that the offi cial stances on this topic formed a very coherent perspective, endorsing the project.

  12. What to Do About That Pack of Wolves at the Door: A Binational Organization and Acquisitions Approach to Homeland Cruise Missile Defense

    Science.gov (United States)

    2016-04-04

    own cruise missile, the Tomahawk. Since then, the United States and Russia have cornered the market in cruise missile technology. For decades the...and low-visibility cruise missiles, and the ability to successfully neutralize large numbers of inbound cruise missiles. The USG also lacks the...well as High Altitude Sensors (HAS) to detect inbound missiles.42 In 2006, Naval Post Graduate students utilized game theory analysis to score all

  13. Strategic Defense Initiative Organization adaptive structures program overview

    Science.gov (United States)

    Obal, Michael; Sater, Janet M.

    In the currently envisioned architecture none of the Strategic Defense System (SDS) elements to be deployed will receive scheduled maintenance. Assessments of performance capability due to changes caused by the uncertain effects of environments will be difficult, at best. In addition, the system will have limited ability to adjust in order to maintain its required performance levels. The Materials and Structures Office of the Strategic Defense Initiative Organization (SDIO) has begun to address solutions to these potential difficulties via an adaptive structures technology program that combines health and environment monitoring with static and dynamic structural control. Conceivable system benefits include improved target tracking and hit-to-kill performance, on-orbit system health monitoring and reporting, and threat attack warning and assessment.

  14. 75 FR 33271 - Information Collection Requirement; Defense Federal Acquisition Regulation Supplement; Foreign...

    Science.gov (United States)

    2010-06-11

    ... Certain Contracts with Foreign Entities for the Conduct of Ballistic Missile Defense Research, Development..., development, test, or evaluation in connection with the Ballistic Missile Defense Program. The provision... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System [OMB Control Number 0704-0229...

  15. Missile sizing for ascent-phase intercept

    Energy Technology Data Exchange (ETDEWEB)

    Hull, D.G. [Univ. of Texas, Austin, TX (United States). Dept. of Aerospace Engineering and Engineering Mechanics; Salguero, D.E. [Sandia National Labs., Albuquerque, NM (United States)

    1994-11-01

    A computer code has been developed to determine the size of a ground-launched, multistage missile which can intercept a theater ballistic missile before it leaves the atmosphere. Typical final conditions for the inteceptor are 450 km range, 60 km altitude, and 80 sec flight time. Given the payload mass (35 kg), which includes a kinetic kill vehicle, and achievable values for the stage mass fractions (0.85), the stage specific impulses (290 sec), and the vehicle density (60 lb/ft{sup 3}), the launch mass is minimized with respect to the stage payload mass ratios, the stage burn times, and the missile angle of attack history subject to limits on the angle of attack (10 deg), the dynamic pressure (60,000 psf), and the maneuver load (200,000 psf deg). For a conical body, the minimum launch mass is approximately 1900 kg. The missile has three stages, and the payload coasts for 57 sec. A trade study has been performed by varying the flight time, the range, and the dynamic pressure Emits. With the results of a sizing study for a 70 lb payload and q{sub max} = 35,000 psf, a more detailed design has been carried out to determine heat shield mass, tabular aerodynamics, and altitude dependent thrust. The resulting missile has approximately 100 km less range than the sizing program predicted primarily because of the additional mass required for heat protection. On the other hand, launching the same missile from an aircraft increases its range by approximately 100 km. Sizing the interceptor for air launch with the same final conditions as the ground-launched missile reduces its launch mass to approximately 1000 kg.

  16. Conventional Prompt Global Strike and Long Range Ballistic Missiles: Background and Issues

    Science.gov (United States)

    2017-02-03

    These include bombers, cruise missiles, ballistic missiles, and boost-glide technologies that would mate a rocket booster with a hypersonic glide...the early stages of development. They are envisioned to launch from air bases, like aircraft, but to travel at speeds that far exceed those of U.S...prototype rocket engine in 2005. 39 According to the Defense Science Board Task Force, this missile might have delivered a 2,000- pound payload over a

  17. An Efficient Missile Loadout Planning Tool for Operational Planners

    Science.gov (United States)

    2017-06-01

    dictionaries to access values for penalties and feasibility checks. VBA user-defined types are created to identify the base set of missions and base...Missile Defense TLAM Tomahawk Land Attack Missiles TSC Tomahawk Strike Coordinator USN United States Navy VBA Visual Basic for Applications VLP... accessible and usable form, we can start basing our loadouts on actual operational plans (OPLAN) and concept plans (CONPLAN). This will give fleet

  18. Test Methods for Short-Range Lethality Evaluation of Full-Scale Hypersonic Kinetic-Energy Missiles

    National Research Council Canada - National Science Library

    Johnson, G. L; Brooks, L. M; Morton, J. L

    2004-01-01

    .... Variables such as terminal dive angle, impact velocity, missile orientation at impact, hit-point on the target, and shot-line through the target all must be carefully controlled and documented...

  19. A low cost maritime control aircraft-ship-weapons system. [antiship missile defense

    Science.gov (United States)

    Fluk, H.

    1981-01-01

    It is pointed out that the long-range antiship standoff missile is emerging as the foremost threat on the seas. Delivered by high speed bombers, surface ships, and submarines, a missile attack can be mounted against selected targets from any point on the compass. An investigation is conducted regarding the configuration of a system which could most efficiently identify and destroy standoff threats before they launch their weapons. It is found that by using ships for carrying and launching missiles, and employing aircraft with a powerful radar only for search and missile directing operations, aircraft cost and weight can be greatly reduced. The employment of V/STOL aircraft in preference to other types of aircraft makes it possible to use ships of smaller size for carrying the aircraft. However, in order to obtain an all-weather operational capability for the system, ships are selected which are still big enough to display the required stability in heavy seas.

  20. A Low-Visibility Force Multiplier: Assessing China’s Cruise Missile Ambitions

    Science.gov (United States)

    2014-04-01

    small radar signature, and very low altitude flight profile of cruise missiles stress air defense systems and airborne surveillance and tracking radars...for engines powering longer-range or large payload cruise missiles and requires a range of disciplines in metallurgy, air flow dynamics, heat ...Beijing-Mos- cow fallout, the Chinese persevered and conducted their first successful missile test in November 1960.3 The Soviets provided China with the

  1. Exploration of 'over kill effect' of high-LET Ar- and Fe-ions by evaluating the fraction of non-hit cell and interphase death

    International Nuclear Information System (INIS)

    Mehnati, P.; Sasaki, Hiroshi; Morimoto, Shigeko; Yatagai, Fumio; Hanaoka, Fumio; Furusawa, Yoshiya; Kanai, Tatsuaki; Kobayashi, Yasuhiko; Wada, Seiichi

    2005-01-01

    The reason why relative biological effectiveness (RBE) for cell killing fell to less than unity (1.0) with very high-linear energy transfer (LET) heavy-ions ( 40 Ar: 1,640 keV/μm; 56 Fe: 780, 1,200, 2,000 keV/μm) was explored by evaluating the fraction of non-hit cell (time-lapse observation) and cells undergoing interphase death (calculation based on our previous data). Chinese hamster ovary (CHO) cells were exposed to 4 Gy (30% survival dose) of Ar (1,640 keV/μm) or Fe-ions (2,000 keV/μm). About 20% of all cells were judged to be non-hit, and about 10% cells survived radiation damage. About 70% cells died after dividing at least once (reproductive death) or without dividing (interphase death). RBE for reproductive (RBE[R]) and interphase (RBE[I]) death showed a similar LET dependence with maximum around 200 keV/μm. In this LET region, at 30% survival level, about 10% non-survivors underwent interphase death. The corresponding value for very high-LET Fe-ions (2,000 keV/μm) was not particularly high (-15%), whereas that for X-rays was less than 3%. However, reproductive death (67%) predominated over interphase death (33%) even in regard to rather severely damaged cells (1% survival level) after exposure to Fe-ions (2,000 keV/μm). These indicate that interphase death is a type of cell death characteristic for the cells exposed to high-LET radiation and is not caused by 'cellular over kill effect'. Both NHF37 (non-hit fraction at 37% survival) and inactivation cross-section for reproductive death (σ[R]) began to increase when LET exceeded 100 keV/μm. The exclusion of non-hit fraction in the calculation of surviving fraction partially prevented the fall of RBE[R] when LET exceeded 200 keV/μm. On the other hand, the mean number of lethal damage per unit dose (NLD/Gy) showed the same LET-dependent pattern as RBE[R]. These suggest that the increase in non-hit fraction and σ[R] with an increasing LET is caused by enhanced clustering of ionization and DNA damage

  2. A Limited Study of a Hypothetical Winged Anti-ICBM Point-Defense Missile

    Science.gov (United States)

    Brown, Clarence A., Jr.; Edwards, Frederick G.

    1959-01-01

    A preliminary investigation was conducted to determine whether a warhead stage of an antimissile missile could be placed within an arbitrary 2-nautical-mile-radius maneuver cylinder around an intercontinental-ballistic-missile (ICBM) flight path above an altitude of 140,000 feet, a horizontal range of 40 nautical miles, at a flight-path angle of approximately 20 deg, and within 50 seconds after take-off using only aerodynamic forces to turn the antimissile missile. The preliminary investigation indicated that an antimissile missile using aerodynamic forces for turning was capable of intercepting the ICBM for the stated conditions of this study although the turning must be completed below an altitude of approximately 70,000 feet to insure that the antimissile missile will be at the desired flight-path angle. Trim lift coefficients on the order of 2 to 3 and a maximum normal-acceleration force of from 25g to 35g were necessary to place the warhead stage in intercept position. The preliminary investigation indicated that for the two boosters investigated the booster having a burning time of 10 seconds gave greater range up the ICBM flight path than did the booster having a burning time of 15 seconds for the same trim lift coefficient and required the least trim lift coefficient for the same range.

  3. EKF-based fault detection for guided missiles flight control system

    Science.gov (United States)

    Feng, Gang; Yang, Zhiyong; Liu, Yongjin

    2017-03-01

    The guided missiles flight control system is essential for guidance accuracy and kill probability. It is complicated and fragile. Since actuator faults and sensor faults could seriously affect the security and reliability of the system, fault detection for missiles flight control system is of great significance. This paper deals with the problem of fault detection for the closed-loop nonlinear model of the guided missiles flight control system in the presence of disturbance. First, set up the fault model of flight control system, and then design the residual generation based on the extended Kalman filter (EKF) for the Eulerian-discrete fault model. After that, the Chi-square test was selected for the residual evaluation and the fault detention task for guided missiles closed-loop system was accomplished. Finally, simulation results are provided to illustrate the effectiveness of the approach proposed in the case of elevator fault separately.

  4. Diode Pumped Alkaline Laser System: A High Powered, Low SWaP Directed Energy Option for Ballistic Missile Defense High-Level Summary - April 2017

    Energy Technology Data Exchange (ETDEWEB)

    Wisoff, P. J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2017-04-28

    The Diode-Pumped Alkali Laser (DPAL) system is an R&D effort funded by the Missile Defense Agency (MDA) underway at Lawrence Livermore National Laboratory (LLNL). MDA has described the characteristics needed for a Boost Phase directed energy (DE) weapon to work against ICBM-class threat missiles. In terms of the platform, the mission will require a high altitude Unmanned Aerial Vehicle (UAV) that can fly in the “quiet” stratosphere and display long endurance – i.e., days on station. In terms of the laser, MDA needs a high power, low size and weight laser that could be carried by such a platform and deliver lethal energy to an ICBM-class threat missile from hundreds of kilometers away. While both the military and industry are pursuing Directed Energy for tactical applications, MDA’s objectives pose a significantly greater challenge than other current efforts in terms of the power needed from the laser, the low size and weight required, and the range, speed, and size of the threat missiles. To that end, MDA is funding two R&D efforts to assess the feasibility of a high power (MWclass) and low SWaP (size, weight and power) laser: a fiber combining laser (FCL) project at MIT’s Lincoln Laboratory, and LLNL’s Diode-Pumped Alkali Laser (DPAL) system.

  5. An overview of the political-military implications of missile proliferation

    International Nuclear Information System (INIS)

    Mahnken, T.

    1990-01-01

    The proliferation of advanced military technology, and of ballistic missiles in particular, should be viewed as a phenomenon with potential strategic ramifications for both the U.S. and its allies. This paper examines these ramifications on three levels: military, politico-military, and geostratigic. Four broad policy approaches can be taken singly or in combination to deal with the ballistic missile threat. They are: arms control, deterrence, preemption, and defense

  6. Application of Pontryagin’s Minimum Principle in Optimum Time of Missile Manoeuvring

    Directory of Open Access Journals (Sweden)

    Sari Cahyaningtias

    2016-11-01

    Full Text Available Missile is a guided weapon and designed to protect outermost island from a thread of other country. It, commonly, is used as self defense. This research presented surface-to-surface missile in final dive manoeuvre for fixed target. Furthermore, it was proposed manoeuvring based on unmanned aerial vehicle (UAV, autopilot system, which needs accuration and minimum both time and thrust of missile while attacking object. This paper introduced pontryagin’s Minimum Principle, which is useable to solve the problem. The numerical solution showed that trajectory of the missile is split it up in three sub-intervals; flight, climbing, and diving. The numerical simulation showed that the missile must climb in order to satisfy the final dive condition and the optimum time of a missile depend on initial condition of the altitude and the terminal velocity

  7. Defense Resource Planning Under Uncertainty: An Application of Robust Decision Making to Munitions Mix Planning

    Science.gov (United States)

    2016-02-01

    Radiation Guided Missile ATACMS Army Tactical Missile System BDA bomb damage assessment C2 command and control CALCM Conventional Air-Launched Cruise Missile...University of Michigan (undated). Figure A.1 Target Selection in WoT 5 6 7 8 9 10 8 6 8 9 10 5 6 7 8 9 10 RAND RR1112-A.1 8 9 10 2 3 3 4 5 6 7 8 9 1 10 BDA ...Follow-on strikesBDA Follow-on strikesBDA Initial strikes Targets in order of priority Follow-on strikes BDA Time Live target Killed

  8. The Regional Dimension of Romania's Participation to the Anti-Missile Defense System

    Directory of Open Access Journals (Sweden)

    Florin Iftode

    2015-08-01

    Full Text Available The current security environment is characterized by a high degree of instability and unpredictability, through the manifestation of new risks and threats, especially those with asymmetrical nature, by redefining the relations between the great powers, and increasing freedom of action of the regional actors (state and non-state. At the international level, the end of the Cold War has led to a fragmentation of efforts in the security field, with direct implications on the need for further efforts of the international community coordination. In this era of profound change and transformation it is not possible the adoption of an isolationist policy of security, but only in a broader context of interdependencies and relationships between general trends, threats or challenges specific to a particular area or geographic areas. Swift operationalization of the anti-missile system will strengthen the national security both directly, through the protection it provides for the entire national territory, and indirectly, as the system will have a deterrent important role, able to mitigate risks of possible attacks by ballistic missiles. The role of deterrence will remove the risk of attack against any Allied territory on which, by virtue of membership in NATO and obligations involved according to article 5 of the Washington Treaty, Romania has also responsibilities.

  9. Missile Defense Acquisition: Failure Is Not An Option

    Science.gov (United States)

    2016-01-26

    Guard in 1988. During his enlistment, he attended Oregon State University where he earned a BS in Economics and subsequently received his...communications system, linking sensor and interceptor networks together to detect and defend the homeland from inbound ballistic missile threats. The GMD...network of sensors to intercept inbound threat ICBMs. MDA refers to the GMD system as, “A network of advanced sensors, radars and command, control

  10. What Should Be the United States Policy towards Ballistic Missile Defense for Northeast Asia?

    National Research Council Canada - National Science Library

    Delgado, Roberto L

    2005-01-01

    .... The threat of ballistic missiles from Northeast Asia is especially high. China and North Korea are seen as the top threats in the region when it comes to the delivery of WMD through ballistic missiles...

  11. Assessment of Turbulence-Chemistry Interactions in Missile Exhaust Plume Signature Analysis

    National Research Council Canada - National Science Library

    Calhoon, W

    2002-01-01

    ... components and missile defense systems. Current engineering level models neglect turbulence chemistry interactions and typically underpredict the intensity of plume afterburning and afterburning burnout...

  12. NATO Pallet with Javelin Missiles, MIL-STD-1660 Tests

    National Research Council Canada - National Science Library

    2004-01-01

    The U.S. Army Defense Ammunition Center (DAC), Validation Engineering Division (SJMAC-DEV) conducted tests in accordance with MIL-STD-1660, "Design Criteria for Ammunition Unit Loads" on the NATO pallet with Javelin missiles...

  13. Seeing 2020: America’s New Vision for Integrated Air and Missile Defense

    Science.gov (United States)

    2015-01-01

    MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION /AVAILABILITY STATEMENT Approved for public release; distribution unlimited 13. SUPPLEMENTARY NOTES 14...siles. Examples included the Nike Zeus and Nike -X anti-ballistic missiles (ABMs), which used nuclear warheads to destroy incoming missiles (a practice...the Soviets also explored) in their terminal phase of flight. Yet despite some successful tests, the Nike programs were never fully implemented

  14. Physics of a ballistic missile defense - The chemical laser boost-phase defense

    Science.gov (United States)

    Grabbe, Crockett L.

    1988-01-01

    The basic physics involved in proposals to use a chemical laser based on satellites for a boost-phase defense are investigated. After a brief consideration of simple physical conditions for the defense, a calculation of an equation for the number of satellites needed for the defense is made along with some typical values of this for possible future conditions for the defense. Basic energy and power requirements for the defense are determined. A sumary is made of probable minimum conditions that must be achieved for laser power, targeting accuracy, number of satellites, and total sources for power needed.

  15. The Anti-Ballistic Missile Treaty

    International Nuclear Information System (INIS)

    Platt, A.

    1991-01-01

    This paper reports that in late May 1972 former President Richard M. Nixon went to Moscow and signed, among other documents, a Treaty to Limit Anti-Ballistic Missile (ABM) Systems. Under this agreement, both the United States and the Soviet Union made a commitment not to build nationwide ABM defenses against the other's intercontinental and submarine-launched ballistic missiles. They agreed to limit ABM deployments to a maximum of two sites, with no more than 100 launchers per site. Thirteen of the treaty's sixteen articles are intended to prevent any deviation from this. In addition, a joint Standing Consultative Commission to monitor compliance was created. National technical means --- sophisticated monitoring devices on land, sea, and in space --- were to be the primary instruments used to monitor compliance with the treaty. The ABM Treaty was signed in conjunction with an Interim Agreement to Limit Strategic Offensive Arms

  16. Anti-Ballistic Missile Laser Predictive Avoidance of Satellites: Theory and Software for Real-Time Processing and Deconfliction of Satellite Ephemerides With a Moving Platform Laser, Book 1

    National Research Council Canada - National Science Library

    vloedman, David

    1999-01-01

    The Anti-Ballistic missile Laser (ABL) Project is committed to defense against attack from enemy-launched Theater Ballistic Missiles using an airborne laser platform to disable an enemy missile in the boost phase of launch...

  17. Deterrence of ballistic missile systems and their effects on today's air operations

    Science.gov (United States)

    Durak, Hasan

    2015-05-01

    Lately, the effect-based approach has gained importance in executing air operations. Thus, it makes more successful in obtaining the desired results by breaking the enemy's determination in a short time. Air force is the first option to be chosen in order to defuse the strategic targets. However, the problems such as the defense of targets and country, radars, range…etc. becoming serious problems. At this level ballistic missiles emerge as a strategic weapon. Ultimate emerging technologies guided by the INS and GPS can also be embedded with multiple warheads and reinforced with conventional explosive, ballistic missiles are weapons that can destroy targets with precision. They have the advantage of high speed, being easily launched from every platform and not being easily detected by air defense systems contrary to other air platforms. While these are the advantages, there are also disadvantages of the ballistic missiles. The high cost, unavailability of nuclear, biological and chemical weapons, and its limited effect while using conventional explosives against destroying the fortified targets are the disadvantages. The features mentioned above should be considered as limitation to the impact of the ballistic missiles. The aim is to impose the requests on enemies without starting a war with all components and to ensure better implementation of the operation functions during the air operations. In this study, effects of ballistic missiles in the future on air battle theatre will be discussed in the beginning, during the process and at the end phase of air operations within the scope of an effect-based approach.

  18. Influence of IR sensor technology on the military and civil defense

    Science.gov (United States)

    Becker, Latika

    2006-02-01

    Advances in basic infrared science and developments in pertinent technology applications have led to mature designs being incorporated in civil as well as military area defense systems. Military systems include both tactical and strategic, and civil area defense includes homeland security. Technical challenges arise in applying infrared sensor technology to detect and track targets for space and missile defense. Infrared sensors are valuable due to their passive capability, lower mass and power consumption, and their usefulness in all phases of missile defense engagements. Nanotechnology holds significant promise in the near future by offering unique material and physical properties to infrared components. This technology is rapidly developing. This presentation will review the current IR sensor technology, its applications, and future developments that will have an influence in military and civil defense applications.

  19. Flowfield and Radiation Analysis of Missile Exhaust Plumes Using a Turbulent-Chemistry Interaction Model

    National Research Council Canada - National Science Library

    Calhoon, W. H; Kenzakowski, D. C

    2000-01-01

    ... components and missile defense systems. Current engineering level models neglect turbulent-chemistry interactions and typically underpredict the intensity of plume afterburning and afterburning burnout...

  20. 75 FR 65439 - Defense Federal Acquisition Regulation Supplement; Electronic Subcontracting Reporting System

    Science.gov (United States)

    2010-10-25

    ... Accounting Service or Missile Defense Agency. (2) For DoD, the authority to acknowledge receipt or reject... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Parts 219 and 252 [DFARS Case 2009-D002] Defense Federal Acquisition Regulation Supplement; Electronic Subcontracting Reporting...

  1. Missile Aerodynamics (Aerodynamique des Missiles)

    Science.gov (United States)

    1998-11-01

    of missiles, and therefore, less money for new developments. New types of international conflicts demand new kinds of missiles and a higher flexibility...us a lower production rate of missiles and, ods, while visualization helps in the development of therefore, less money for new developments. New...du mod~le de turbulence. Plusieurs Lauder [1 ~ 3].maillages distincts ont 6t 6tudi6s. Ils different essentiellement par le nombre de points dans la

  2. U.S. MISSILE DEFENSE SITE IN EUROPE AS AN ALLIANCE SECURITY DILEMMA

    Directory of Open Access Journals (Sweden)

    Lukáš Kantor

    2011-12-01

    Full Text Available The main aim of this article is to provide a more solid theoretical anchor for numerous past and present debates about the various versions of American missile defence in Europe. The author claims that the neo-realism’s concept of alliance security dilemma is the most appropriate framework for Czech, Polish, Romanian, and EU-wide experts‘reflections and political decisions regarding the possible accepting of elements of American or NATO missile defence. Under appreciated explanatory power of the concept of the alliance‘s security dilemma is illustrated in the text on the case of the original Bush‘s plan of the so-called third pillar in Poland and the Czech Republic.

  3. System Architecture for Anti-Ship Ballistic Missile Defense (ASBMD)

    OpenAIRE

    Hobgood, Jean; Madison, Kimberly; Pawlowski, Geoffrey; Nedd, Steven; Roberts, Michael; Rumberg, Paige

    2009-01-01

    Approved for public release; distribution is unlimited. Recent studies suggest that China is developing a new class of ballistic missiles that can be used against moving targets, such as ships. One such technology is anticipated to cover a range of 2,000 kilometers and operate at a speed of Mach 10. The threat is also capable of maneuvering both during the midcourse and terminal flight phases for the purposes of guidance, target acquisition, and countermeasures. This threat could greatl...

  4. The Evolution of the Cruise Missile

    Science.gov (United States)

    1985-09-01

    Fallersleben four times, the gyro factory at Weimar once, hydrogen peroxide facilities (used in the V-I’s booster) at Peenemunde, Holliegelshreuth, and...uirilar attitudes towards RPVs see William Wagner , bgAtnim Bugs a.’ O0 erReconissance•Drowes (Falibrook, Calif.: Aero, 1982), (iii, ivy. 54. General...of the cruise missile. Shown taking the oath of office from Secretary of Defense Robert McNamara (right) on 1 October 1965 wre (left to right) Norman

  5. Ballistic Missile Defense: An Administration Perspective

    National Research Council Canada - National Science Library

    Bell, Robert

    1995-01-01

    ...: "What is our strategy?" What the Clinton Administration is doing with regard to strategic offensive systems provides an instructive context for what we re now trying to do on the strategic defensive side...

  6. Strategic Defense Initiative Organization: Corporate Plan

    National Research Council Canada - National Science Library

    1992-01-01

    ... requires a flexible yet focused approach to attain its mission; namely, to research, develop, acquire, and deploy systems and technologies which provide ballistic missile defense to include Global Protection Against Limited Strikes (OPALS...

  7. Tactical missile aerodynamics

    Science.gov (United States)

    Hemsch, Michael J. (Editor); Nielsen, Jack N. (Editor)

    1986-01-01

    The present conference on tactical missile aerodynamics discusses autopilot-related aerodynamic design considerations, flow visualization methods' role in the study of high angle-of-attack aerodynamics, low aspect ratio wing behavior at high angle-of-attack, supersonic airbreathing propulsion system inlet design, missile bodies with noncircular cross section and bank-to-turn maneuvering capabilities, 'waverider' supersonic cruise missile concepts and design methods, asymmetric vortex sheding phenomena from bodies-of-revolution, and swept shock wave/boundary layer interaction phenomena. Also discussed are the assessment of aerodynamic drag in tactical missiles, the analysis of supersonic missile aerodynamic heating, the 'equivalent angle-of-attack' concept for engineering analysis, the vortex cloud model for body vortex shedding and tracking, paneling methods with vorticity effects and corrections for nonlinear compressibility, the application of supersonic full potential method to missile bodies, Euler space marching methods for missiles, three-dimensional missile boundary layers, and an analysis of exhaust plumes and their interaction with missile airframes.

  8. Targeted Killing as an Element of U.S. Foreign Policy in the War On Terror

    National Research Council Canada - National Science Library

    Machon, Matthew J

    2006-01-01

    ...) launched a lethal missile strike, killing Qaed Salim Sinan al-Harethi, a high ranking al-Qaeda member and suspected architect of the USS Cole bombing, in an isolated and sparsely populated region within Yemen...

  9. Defense Space Support to Civil Authority: How Can Policy be Improved?

    Science.gov (United States)

    2010-06-11

    former Russian KGB agent, is killed by Polonium - 210 in a London sushi bar. NOV 2006 Iran successfully test-fires 3 new models of sea missiles in a show of...Infrastructure Protection Mass Care (Sheltering, Feeding, and Related Services) Epidemiological Surveillance and Investigation Mass Prophylaxis Food and...Radiological Attack 12 Explosives Attack - IED 13 Biological Attack - Food contamination 14 Biological Attack - Foreign Animal Disease 15 Cyber

  10. 77 FR 76938 - Defense Federal Acquisition Regulation Supplement: Contracting Activity Updates (DFARS Case 2012...

    Science.gov (United States)

    2012-12-31

    ... Security Cooperation Agency, the Defense Security Service, the Defense Threat Reduction Agency, the Missile... DEPARTMENT OF DEFENSE Defense Acquisition Regulations System 48 CFR Part 202 RIN 0750-AH81 Defense...: Defense Acquisition Regulations System, Department of Defense (DoD). ACTION: Final rule. SUMMARY: DoD is...

  11. Do European Union Defense Initiatives Threaten NATO? Strategic Forum. Number 184, August 2001

    National Research Council Canada - National Science Library

    Schake, Kori

    2001-01-01

    ...) Although transatlantic policies will be colored by issues such as the Kyoto treaty, missile defenses, and relations with Russia, ESDP is likely to dominate defense debates as the European Union (EU...

  12. Army National Guard Air Defense Artillery Modernization: A Vision for the Future

    Science.gov (United States)

    1994-05-15

    plan to replace Stinger Under Armor (SUA) for the ARNG, and no guarantee that the BSFV will be in the future ARNG force, divisional assets will remain...Ballistic Missile SUA Stinger Under Armor TAA Total Army Analysis TAAD Theater Area Air Defense TASM Tactical Air-to-Surface Missiles TBM Tactical

  13. The One-on-One Stochastic Duel. Parts I and II

    Science.gov (United States)

    1979-04-15

    University Microfilms, Inc., Ann Arbor, Michigan, No. M16f7) FM - CRIFT r miss 3 states hit, not killed hit, killed P[hit] -p, a constant; P[miss) - -p; and P...AB] Numerical examples Harkov chains number theory - matrix maniplations geoetric transforms B-3 * H 1. HARRIS, Terrell J., "In•y Versus )arz...34 Master’s Thesis, Dept. of Industrial Engineering, University of Michigan, Ann Arbor, Michigan, 8 August, 1968.) (Also, DSL C2147 WP 68-4(U), Defense

  14. Missile proliferation and missile defence

    International Nuclear Information System (INIS)

    Marin-Bosch, Miguel

    2002-01-01

    Nothing should serve to justify the acquisition and development of ballistic missiles. The solution to this problem is similar to that of all weapons of mass destruction, including nuclear weapons, i.e., a total ban of their use, testing, manufacture and development. Unfortunately, given the present international climate, ballistic missiles will continue to be an important component of the arsenals of several countries for years to come. ...what you invent today to enhance your security has a tendency to reappear later elsewhere as a threat. (author)

  15. Controlling ballistic missiles: How important? How to do it?

    International Nuclear Information System (INIS)

    Harvey, J.R.; Rubin, U.

    1992-01-01

    Missiles themselves are not weapons of mass destruction; they do not give states the ability to wreak unimaginable destruction, or to radically shift the balance of power, as nuclear weapons do. Hence, the primary focus of nonproliferation efforts should remain on weapons of mass destruction, particularly nuclear weapons, rather than on one of the many possible means of delivering them. Moreover, as discussed in more detail below, advanced strike aircraft can also be effective in delivering nuclear weapons, and are generally more effective than ballistic missiles for delivering conventional or chemical ordnance. Ultimately, if the industrialized nations seriously desire to control the spread of delivery means for weapons of mass destruction, they need to consider bringing controls over ballistic missiles and advanced strike aircraft more into balance. At the same time, while efforts to control ballistic missile proliferation - centered on the Missile Technology Control Regime (MTCR) - have had some successes and could be strengthened, US policy will be most effective if it recognizes two key realities: the spread of ballistic missiles cannot be as comprehensively controlled as the spread of nuclear weapons, nor need it be as comprehensively controlled

  16. A joint mid-course and terminal course cooperative guidance law for multi-missile salvo attack

    Directory of Open Access Journals (Sweden)

    Jie ZENG

    2018-06-01

    Full Text Available Salvo attacking a surface target by multiple missiles is an effective tactic to enhance the lethality and penetrate the defense system. However, existing cooperative guidance laws in the mid-course or terminal course are not suitable for long- and medium-range missiles or stand-off attacking. Because the initial conditions of cooperative terminal guidance that are generally generated from the mid-course flight may not lead to a successful cooperative terminal guidance without proper mid-course flight adjustment. Meanwhile, cooperative guidance in the mid-course cannot solely guarantee the accuracy of a simultaneous arrival of multiple missiles. Therefore, a joint mid-course and terminal course cooperative guidance law is developed. By building a distinct leader-follower framework, this paper proposes an efficient coordinated Dubins path planning method to synchronize the arrival time of all engaged missiles in the mid-course flight. The planned flight can generate proper initial conditions for cooperative terminal guidance, and also benefit an earliest simultaneous arrival. In the terminal course, an existing cooperative proportional navigation guidance law guides all the engaged missiles to arrive at a target accurately and simultaneously. The integrated guidance law for an intuitive application is summarized. Simulations demonstrate that the proposed method can generate fast and accurate salvo attack. Keywords: Cooperative systems, Dubins path, Mid-course flight, Missile guidance, Salvo attack

  17. Curved electromagnetic missiles

    International Nuclear Information System (INIS)

    Myers, J.M.; Shen, H.M.; Wu, T.T.

    1989-01-01

    Transient electromagnetic fields can exhibit interesting behavior in the limit of great distances from their sources. In situations of finite total radiated energy, the energy reaching a distant receiver can decrease with distance much more slowly than the usual r - 2 . Cases of such slow decrease have been referred to as electromagnetic missiles. All of the wide variety of known missiles propagate in essentially straight lines. A sketch is presented here of a missile that can follow a path that is strongly curved. An example of a curved electromagnetic missile is explicitly constructed and some of its properties are discussed. References to details available elsewhere are given

  18. FY 1972-1976 Defense Program and the 1972 Defense Budget.

    Science.gov (United States)

    1971-03-01

    Thai Government. This assessment was given me by Thai officials during my recent visit there. Insurgents along the Thai/ Malaysian border are under the...Development and Initial Procurement of Maverick Air-to-Ground Missile 31 87 Air Superiority and Air Defense Continued Procurement of F-4 Air Force Fighter... MAVERICK . The MAVERICK is another program that is of importance in providing increased capabilities for support of troops on the battlefield. MAVERICK is

  19. Health Information Technology (HIT) Adaptation: Refocusing on the Journey to Successful HIT Implementation.

    Science.gov (United States)

    Yen, Po-Yin; McAlearney, Ann Scheck; Sieck, Cynthia J; Hefner, Jennifer L; Huerta, Timothy R

    2017-09-07

    In past years, policies and regulations required hospitals to implement advanced capabilities of certified electronic health records (EHRs) in order to receive financial incentives. This has led to accelerated implementation of health information technologies (HIT) in health care settings. However, measures commonly used to evaluate the success of HIT implementation, such as HIT adoption, technology acceptance, and clinical quality, fail to account for complex sociotechnical variability across contexts and the different trajectories within organizations because of different implementation plans and timelines. We propose a new focus, HIT adaptation, to illuminate factors that facilitate or hinder the connection between use of the EHR and improved quality of care as well as to explore the trajectory of changes in the HIT implementation journey as it is impacted by frequent system upgrades and optimizations. Future research should develop instruments to evaluate the progress of HIT adaptation in both its longitudinal design and its focus on adaptation progress rather than on one cross-sectional outcome, allowing for more generalizability and knowledge transfer. ©Po-Yin Yen, Ann Scheck McAlearney, Cynthia J Sieck, Jennifer L Hefner, Timothy R Huerta. Originally published in JMIR Medical Informatics (http://medinform.jmir.org), 07.09.2017.

  20. Modulation of pulmonary defense mechanisms by acute exposures to nitrogen dioxide

    International Nuclear Information System (INIS)

    Jakab, G.J.

    1987-01-01

    The effect of acute exposures to NO 2 on the antibacterial defenses of the murine lung was assessed following inhalation challenges with Staphylococcus aureus, Proteus mirabilis, and Pasteurella pneumotropica. With S. aureus pulmonary antibacterial defenses were suppressed at NO 2 levels of 4.0 ppm and greater. Exposure to 10.0 ppm enhanced the intrapulmonary killing of P. mirabilis which correlated with an increase in the phagocytic cell populations lavaged from the lungs; at 20.0 ppm bactericidal activity against P. mirabilis was impaired. Pulmonary antibacterial defenses against P. pneumotropica were impaired at 10.0 ppm which correlated with a decrease in the retrieved phagocytic lung cell population. Reversing the order of treatment (ie., NO 2 exposure prior to bacterial challenge) raised the threshold concentration for NO 2 -induced impairment of intrapulmonary bacterial killing. With S. aureus the effect was not observed at 5.0 ppm but at 10.0 ppm and with P. mirabilis not at 20.0 ppm but at 30.0 ppm intrapulmonary killing was enhanced. Exposures up to 20.0 ppm of NO 2 did not effect the physical translocation mechanisms of the lung as quantitated by declines in pulmonary radiotracer activity following aerogenic challenge with 32 P-labeled staphylococci

  1. Capturing asteroids into bound orbits around the earth: Massive early return on an asteroid terminal defense system

    International Nuclear Information System (INIS)

    Hills, J.G.

    1992-01-01

    Nuclear explosives may be used to capture small asteroids (e.g., 20--50 meters in diameter) into bound orbits around the earth. The captured objects could be used for construction material for manned and unmanned activity in Earth orbit. Asteroids with small approach velocities, which are the ones most likely to have close approaches to the Earth, require the least energy for capture. They are particularly easy to capture if they pass within one Earth radius of the surface of the Earth. They could be intercepted with intercontinental missiles if the latter were retrofit with a more flexible guiding and homing capability. This asteroid capture-defense system could be implemented in a few years at low cost by using decommissioned ICMs. The economic value of even one captured asteroid is many times the initial investment. The asteroid capture system would be an essential part of the learning curve for dealing with larger asteroids that can hit the earth

  2. Cooperative Monitoring Center Occasional Paper/4: Missile Control in South Asia and the Role of Cooperative Monitoring Technology

    Energy Technology Data Exchange (ETDEWEB)

    Kamal, N.; Sawhney, P.

    1998-10-01

    The succession of nuclear tests by India and Pakistan in May 1998 has changed the nature of their missile rivalry, which is only one of numerous manifestations of their relationship as hardened adversaries, deeply sensitive to each other's existing and evolving defense capabilities. The political context surrounding this costly rivalry remains unmediated by arms control measures or by any nascent prospect of detente. As a parallel development, sensible voices in both countries will continue to talk of building mutual confidence through openness to avert accidents, misjudgments, and misinterpretations. To facilitate a future peace process, this paper offers possible suggestions for stabilization that could be applied to India's and Pakistan's missile situation. Appendices include descriptions of existing missile agreements that have contributed to better relations for other countries as well as a list of the cooperative monitoring technologies available to provide information useful in implementing subcontinent missile regimes.

  3. Reasons Behind the Change of American Ballistic Missile Defense Architecture in Europe

    Directory of Open Access Journals (Sweden)

    Radovan EUGEL

    2010-12-01

    Full Text Available The article analyses the change of the architecture of American ballistic missile system in Europe by Barrack Obama in September 2009. The author argues that this change was partially, but not solely, motivated by the effort to appease the Russian antagonism against this project. This is supported by various arguments for and against the assertion that it was an effort to appease Russia. Thus, the answer should be somewhere in the middle.

  4. Characteristics of tornado generated missiles

    International Nuclear Information System (INIS)

    Bhattacharyya, A.K.; Boritz, R.C.; Niyogi, P.K.

    1975-10-01

    The development of techniques designed to calculate tornado missile velocities is traced. It is shown that there is a need for a consistent method for obtaining missile velocities for a variety of tornado parameters. A consistent method for determination of trajectories and velocities of missiles generated by a tornado is described. The effects of plant layout upon missile impact velocity at a given building are discussed from the point of view of determining the necessary missile barrier characteristics. 19 references

  5. Defense Technology Journal, Vol. 16, No. 2, February 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-02-01

    ;Contents: VERTIGO Simulation; Education Reform of National Defense Academy; Artilleries and Ammunitions (4); Newly developed encryption algorithm (MISTY) that surpasses DES; CAS EXPO`95 in California USA; Underwater Weapons; Phaser Gun; and Japanese Missile.

  6. Nanotechnology for missiles

    Science.gov (United States)

    Ruffin, Paul B.

    2004-07-01

    Nanotechnology development is progressing very rapidly. Several billions of dollars have been invested in nanoscience research since 2000. Pioneering nanotechnology research efforts have been primarily conducted at research institutions and centers. This paper identifies developments in nanoscience and technology that could provide significant advances in missile systems applications. Nanotechnology offers opportunities in the areas of advanced materials for coatings, including thin-film optical coatings, light-weight, strong armor and missile structural components, embedded computing, and "smart" structures; nano-particles for explosives, warheads, turbine engine systems, and propellants to enhance missile propulsion; nano-sensors for autonomous chemical detection; and nano-tube arrays for fuel storage and power generation. The Aviation and Missile Research, Development, and Engineering Center (AMRDEC) is actively collaborating with academia, industry, and other Government agencies to accelerate the development and transition of nanotechnology to favorably impact Army Transformation. Currently, we are identifying near-term applications and quantifying requirements for nanotechnology use in Army missile systems, as well as monitoring and screening research and developmental efforts in the industrial community for military applications. Combining MicroElectroMechanical Systems (MEMS) and nanotechnology is the next step toward providing technical solutions for the Army"s transformation. Several research and development projects that are currently underway at AMRDEC in this technology area are discussed. A top-level roadmap of MEMS/nanotechnology development projects for aviation and missile applications is presented at the end.

  7. Hitting the Sweet Spot: Glycans as Targets of Fungal Defense Effector Proteins

    Directory of Open Access Journals (Sweden)

    Markus Künzler

    2015-05-01

    Full Text Available Organisms which rely solely on innate defense systems must combat a large number of antagonists with a comparatively low number of defense effector molecules. As one solution of this problem, these organisms have evolved effector molecules targeting epitopes that are conserved between different antagonists of a specific taxon or, if possible, even of different taxa. In order to restrict the activity of the defense effector molecules to physiologically relevant taxa, these target epitopes should, on the other hand, be taxon-specific and easily accessible. Glycans fulfill all these requirements and are therefore a preferred target of defense effector molecules, in particular defense proteins. Here, we review this defense strategy using the example of the defense system of multicellular (filamentous fungi against microbial competitors and animal predators.

  8. Why even good defenses may be bad

    International Nuclear Information System (INIS)

    Glaser, C.L.

    1984-01-01

    The current debate over whether an effective ballistic missile defense (BMD) is technically feasible and whether it could be developed and deployed has left most of the advocacy up to those supporting a BMD program. The author emphasizes the issues beyond technical feasibility in his conclusion that assured destruction may still be preferable to perfect defense in terms of reducing the probability of nuclear war. After examining a number of possible scenarios involving the US and Soviet Union, the positions of allies, and the possibility of clandestine bombs, he sees no reason to expect that a defense system would be less vulnerable or have fewer uncertainties. 29 references

  9. Trade-off Study for the Hit-to-kill Interception of Ballistic Missiles in the Boost Phase

    Science.gov (United States)

    2009-12-01

    8217nearest’,’ extrap ’); %interpolate the Cd data in the array for the new Mach number CL_curve = interp1(CL_data(:,1),CL_data(:,2:11),M,’nearest...8217,’ extrap ’); %interpolate the CL data in the array for the new Mach number p = polyfit(CL_curve,Cd_curve,2); % generate a new drag polar (CL_Cd

  10. Naval Theater Ballistic Missile Defense (TBMD): development of the information exchange requirements

    OpenAIRE

    Brintzinghoffer, Daniel M.

    1996-01-01

    As the United States moves into the next century one of the biggest threats facing her national interests is the proliferation of Theater Ballistic Missile (TBM) Systems, with their potential for carrying Weapons of Mass Destruction(WMD). In order for the United States to 'project power', the Navy must play a large role in the protection of friendly assets from TBM attacks. Thus, the Navy is continuing to develop new systems and technologies as it attempts to migrate older weapons systems to ...

  11. Navy Aegis Ballistic Missile Defense (BMD) Program: Background and Issues for Congress

    Science.gov (United States)

    2016-10-25

    to be forward-homeported (i.e., based) at the naval base at Rota, Spain.10 The four ships are the destroyers Ross (DDG-71) and Donald Cook (DDG- 75...the French , who have been watching this.” Though NATO is not affiliated with the MTMD Forum, most of the 10 forum members are in NATO—Australia...talking to Aster 30 partners France and Italy about developing an extended-range version of a missile already used by the French and Italian armies to

  12. The US ballistic missile defence policy in the Baltic and Nordic regions

    Directory of Open Access Journals (Sweden)

    Konyshev Valery

    2016-03-01

    Full Text Available This article examines the implications of the deployment of the US ballistic missile defense (BMD system in the Baltic and Nordic regions. These implications are to be considered to ensure Russia’s military security. Using the structural-functional method, the authors analyse the internal structure of the US BMD in Europe, stages of its implementation, and its influence on the military equilibrium in the region. Being similar to other regional missile defence systems of the Pentagon, BMD in Europe increases the offensive capabilities of the US armed forces and its allies and in doing so, it stops performing a purely defensive mission declared by Washington. It is stressed that the deployment of mobile sea- and land-based BMD elements in the Baltic Sea region and Nordic countries will inevitably destabilize the strategic situation and may lead to a new round of arms race in the region. The efficacy of BMD in Europe is evaluated from the perspective of military technology. The system’s potential threats to Russia’s military security and its armed forces are assessed. The article considers measures to enhance national security that could be taken by Russia provided the US plans to deploy BMD in Europe are fully implemented.

  13. 33 CFR 334.1440 - Pacific Ocean at Kwajalein Atoll, Marshall Islands; missile testing area.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Pacific Ocean at Kwajalein Atoll, Marshall Islands; missile testing area. 334.1440 Section 334.1440 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE DANGER ZONE AND RESTRICTED AREA REGULATIONS § 334.1440 Pacific Ocean at Kwajalein...

  14. Tornado-borne missile speeds. Final report

    International Nuclear Information System (INIS)

    Simiu, E.; Cordes, M.

    1976-04-01

    An investigation of the question of tornado-borne missile speeds was carried out, with a view to identify pertinent areas of uncertainty and to estimate credible tornado-borne missile speeds - within the limitations inherent in the present state of the art. The investigation consists of two parts: (1) a study in which a rational model for the missile motion is proposed, and numerical experiments are carried out corresponding to various assumptions on the initial conditions of the missile motion, the structure of the tornado flow, and the aerodynamic properties of the missile; (2) a theoretical and experimental study of tornado-borne missile aerodynamics, conducted by Colorado State Univ. (CSU) to be covered in a separate report by CSU. In the present report, the factors affecting missile motion and their influence upon such motion are examined

  15. Missile rolling tail brake torque system. [simulating bearing friction on canard controlled missiles

    Science.gov (United States)

    Davis, W. T. (Inventor)

    1984-01-01

    Apparatus for simulating varying levels of friction in the bearings of a free rolling tail afterbody on a canard-controlled missile to determine friction effects on aerodynamic control characteristics is described. A ring located between the missile body and the afterbody is utilized in a servo system to create varying levels of friction between the missile body and the afterbody to simulate bearing friction.

  16. Politics and Defense Capabilities: Local Interests versus Strategic Imperatives

    Science.gov (United States)

    2014-01-01

    SPONSOR/MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION /AVAILABILITY STATEMENT Approved for public release; distribution unlimited 13. SUPPLEMENTARY...137 million for the Nike -Zeus missile system. And John Kennedy, on the advice of Secretary of Defense Robert McNamara, withheld $180 million to end

  17. Effect of Shark Liver Oil on Peritoneal Murine Macrophages in Responses to Killed-Candida albicans

    Directory of Open Access Journals (Sweden)

    Monire Hajimoradi

    2009-09-01

    Full Text Available Objective(sShark Liver Oil (SLO is an immunomodulator. Macrophages play a key role in host defense against pathogens like fungi. Candida albicans have mechanisms to escape immune system. We determined the effect of killed-Candida on the in vitro viability of macrophages and the effect of SLO on augmentation of this potency.Materials and MethodsPeritoneal macrophages were separated and cultured (3×105/well. At first, the effect of killed-Candida (200 cells/well on macrophage viability was evaluated, using MTT test. Then, MTT was performed on macrophages stimulated with killed-Candida in the presence of SLO. ResultsKilled-Candida suppressed the ability of MTT reduction and hence macrophages viability (P=0.026, but addition of SLO (100 mg/ml significantly enhanced cell viability (P=0.00. So, SLO could neutralize the inhibitory effect of Candida.ConclusionSimultaneous with cytotoxic effect of killed-Candida cells on macrophages viability, SLO augment macrophages viability. So, it can be applied in candidiasis as a complement.

  18. China and Proliferation of Weapons of Mass Destruction and Missiles: Policy Issues

    Science.gov (United States)

    2012-11-07

    hundreds of tons of anhydrous hydrogen fluoride (AHF), or hydrofluoric acid , under falsified documents about end-users. (The AHF chemical could be used to...Chinese Nuclear Tests, 1964-1996,” Physics Today, September 2008; Alex Kingsbury, “ Why China Helped Countries Like Pakistan, North Korea Build Bombs,” U.S...Japan and South Korea; (6) a stronger Japan (with missile defense and even possibly nuclear weapons); (7) stability and PRC influence in a weak North

  19. Statistics of hits to bone cell nuclei

    International Nuclear Information System (INIS)

    Kruglikov, I.L.; Polig, E.; Jee, W.S.S.

    1993-01-01

    The statistics of hits to the nuclei of bone cells irradiated from alpha sources labeling bone tissue is described. It is shown that the law of remodeling of a bone structural unit (BSU), which describes the distribution of quiescence periodes of this unit, affects the statistics of hits. It the irradiation of bone cells occurs during the whole cell cycle, the mean number of hits is independent of the law of remodeling. In this case the variance of hits has the minimum value for constant quiescence periods of BSUs (deterministic remodeling) and the maximum value for exponentially distributed quiescence periods (random remodeling). For the first generation of bone cells, i.e. for the cells which existed at the moment of the uptake of the nuclide, the mean number of hits depends on the law of remodeling. For random remodeling the mean number is equal to the mean value for the complete remodeling cycle. For deterministic remodeling the mean is only half this value. For the first generation of bone cells, changing the law of remodeling from random to deterministic increases the probability of no hits to the nuclei of bone cells. For the same mean value of hits, the difference does not exceed 13.3% of the total number of cells. For the subsequent generations of bone cells, such a change of the law of remodeling decreases the probability of no hits up to 20.4% of the total number of cells. (orig.)

  20. Analyzing and designing object-oriented missile simulations with concurrency

    Science.gov (United States)

    Randorf, Jeffrey Allen

    2000-11-01

    A software object model for the six degree-of-freedom missile modeling domain is presented. As a precursor, a domain analysis of the missile modeling domain was started, based on the Feature-Oriented Domain Analysis (FODA) technique described by the Software Engineering Institute (SEI). It was subsequently determined the FODA methodology is functionally equivalent to the Object Modeling Technique. The analysis used legacy software documentation and code from the ENDOSIM, KDEC, and TFrames 6-DOF modeling tools, including other technical literature. The SEI Object Connection Architecture (OCA) was the template for designing the object model. Three variants of the OCA were considered---a reference structure, a recursive structure, and a reference structure with augmentation for flight vehicle modeling. The reference OCA design option was chosen for maintaining simplicity while not compromising the expressive power of the OMT model. The missile architecture was then analyzed for potential areas of concurrent computing. It was shown how protected objects could be used for data passing between OCA object managers, allowing concurrent access without changing the OCA reference design intent or structure. The implementation language was the 1995 release of Ada. OCA software components were shown how to be expressed as Ada child packages. While acceleration of several low level and other high operations level are possible on proper hardware, there was a 33% degradation of 4th order Runge-Kutta integrator performance of two simultaneous ordinary differential equations using Ada tasking on a single processor machine. The Defense Department's High Level Architecture was introduced and explained in context with the OCA. It was shown the HLA and OCA were not mutually exclusive architectures, but complimentary. HLA was shown as an interoperability solution, with the OCA as an architectural vehicle for software reuse. Further directions for implementing a 6-DOF missile modeling

  1. 33 CFR 334.720 - Gulf of Mexico, south from Choctawhatchee Bay; guided missiles test operations area, Headquarters...

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Gulf of Mexico, south from..., DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE DANGER ZONE AND RESTRICTED AREA REGULATIONS § 334.720 Gulf of Mexico, south from Choctawhatchee Bay; guided missiles test operations area, Headquarters Air Proving...

  2. Back to the Future: Integrated Air and Missile Defense in the Pacific

    Science.gov (United States)

    2015-02-01

    US assets with those of our allies and partners, we have optimized our defense design, pre- venting the waste of precious interceptors. The Pacific...Good Offense: Attack Operations Power projection is, and always will be, th e bread and butter of the US Air Force. Only the United States can

  3. Ballistic Missile Defense FY95 Funding & Language Track

    Science.gov (United States)

    1994-10-01

    io o 0) "> SI Q) to a-, H~ TO CD TO - m fe o c ■Q </) Q> V) 0) TO JO "Js ^" ** 5<o c Q> E E o o 0) Tj Ü TO SSto ...Defense Act National SSTO National Test Facility Upper Lower Tier Risk Reduction Report ABM Treaty NMD TMD Early Warnin Pages: 00247 Cataloged Date: May

  4. 15 CFR 742.5 - Missile technology.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Missile technology. 742.5 Section 742... BASED CONTROLS § 742.5 Missile technology. (a) License requirements. (1) In support of U.S. foreign... establish the existence of a contract. (d) Missile Technology Control Regime. Missile Technology Control...

  5. Heparin-independent, PF4-dependent binding of HIT antibodies to platelets: implications for HIT pathogenesis.

    Science.gov (United States)

    Padmanabhan, Anand; Jones, Curtis G; Bougie, Daniel W; Curtis, Brian R; McFarland, Janice G; Wang, Demin; Aster, Richard H

    2015-01-01

    Antibodies specific for platelet factor 4 (PF4)/heparin complexes are the hallmark of heparin-induced thrombocytopenia and thrombosis (HIT), but many antibody-positive patients have normal platelet counts. The basis for this is not fully understood, but it is believed that antibodies testing positive in the serotonin release assay (SRA) are the most likely to cause disease. We addressed this issue by characterizing PF4-dependent binding of HIT antibodies to intact platelets and found that most antibodies testing positive in the SRA, but none of those testing negative, bind to and activate platelets when PF4 is present without any requirement for heparin (P HIT antibodies recognize PF4 in a complex with heparin, only a subset of these antibodies recognize more subtle epitopes induced in PF4 when it binds to CS, the major platelet glycosaminoglycan. Antibodies having this property could explain "delayed HIT" seen in some individuals after discontinuation of heparin and the high risk for thrombosis that persists for weeks in patients recovered from HIT. © 2015 by The American Society of Hematology.

  6. The behavior of reinforced concrete barriers subjected to the impact of tornado generated deformable missiles

    International Nuclear Information System (INIS)

    McMahon, P.M.; Meyers, B.L.; Buchert, K.P.

    1977-01-01

    The paper presents a general model for the evaluation of local effects damage including, penetration and backface spalling, of reinforced concrete barriers subjected to the impact of deformable tornado generated missiles. The model is based on an approximte force time history which assumes: 1) the initial penetration of the missile occurs without significant deformation of the missile if the strength of the missile is greater than that of the barrier. This portion of the time history is represented by a linear and finite rise time; 2) wrinkling or collapse of the missile occurs when the critical stress of the missile is exceeded. This portion of the time histroy is represented by a constant force-time relationship, although a decreaseing force might be more accurate; 3) while the missile is penetrating and wrinkling both elastic and plastic stress waves are developed in the missile, and compressive and shear stress waves are generated in he target. When the shear waves reach the backface of the slab, doagonal cracks initiating at the end of the penetrating missile are formed. These cracks propagate to the backface reinforcing where splitting cracks are formed. Finally, yield hinge lines form in the plane of reinforcing; 4) repenetration of the missile occurs after the wrinkling has caused a change in missile cross section. This repenetration results from moving the failure cone described in three above, and is also represented by the costant force time history. Using the assumptions, relationships for the penetration depth of the missile the wrinkling length of the missile, the critical missile stress, the time history of the impact and the spalling of the target are developed. (Auth.)

  7. Annual Industrial Capabilities Report to Congress

    Science.gov (United States)

    2010-05-01

    programs that had issues with performance, cost, or rationale. Specifically, Secretary Gates terminated: • The Multiple Kill Vehicle missile...Schering- Plough $41,000 No Objection Pharmaceuticals Microsemi Semicoa $25 Objected. Supported Divestiture Space-Qualified Transistors & Diodes Nammo...Atmospheric Kill Vehicle (EKV) and Standard Missile-3 (SM-3) detector and camera enhancements; 3) continue DoD, MDA and NASA investments in order to

  8. Potential hazard to secondary containment from HCDA-generated missiles and sodium fires

    International Nuclear Information System (INIS)

    Romander, C.M.

    1979-02-01

    The potential hazard of HCDA-generated missiles is analyzed, and the current status of the potential hazards of sodium fires is summarized. Simple analyses are performed to determine lower bounds on the HCDA energetics required to generate missiles that could reach the secondary containment structure of a 1000-MWe LMFBR. The potential missiles considered include the vessel head, components mounted on the head, and conrol rods

  9. Tornado missiles protections taken at the Ikata NPP of SEPCO

    International Nuclear Information System (INIS)

    Ikeda, Kazutoyo; Takagi, Toshimitsu; Inoue, Haruhisa; Yoshida, Hisao; Moriuchi, Takehiro

    2014-01-01

    On July 8, 2013, the new regulatory requirements for commercial power reactors got in force. Based on a concept of 'Defense-in-depth', essential importance was placed on the third and fourth layers of defense and prevention of simultaneous loss of all safety functions due to common causes. In this regards, the previous assumptions on the impact of earthquakes, tsunamis and other external events such as volcanic eruptions, tornadoes and forest fires were re-evaluated, and countermeasures for nuclear safety against these external events were decided to be enhanced. For tornado, Nuclear Regulation Authority promulgated the 'Assessment Guide for Tornado Effect on Nuclear Power Plants' to evaluate the effect of tornadoes. This paper will introduce the outline of evaluation cases of tornado effect, and tornado missiles protections taken at the Ikata Unit 3 Nuclear Power Plant (for actual case studies). (author)

  10. Probabilistic analysis of turbine missile damage to nuclear power plant structures

    International Nuclear Information System (INIS)

    Twisdale, L.A.; Dunn, W.L.; Frank, R.A.

    1983-01-01

    This paper summarizes the results of the EPRI project that focused on the development of the overall probabilistic methodology to assess the risks of turbine missile induced damage to nuclear power plant structures and components. The project was structured to use the results of other EPRI projects that provided information on turbine failure and missile generation frequencies, models to predict the characteristics and exit conditions of the missiles, and experimental data for use in updating empirical impact formulas for reinforced concrete barriers. The research effort included: (1) adaptation and implementation of the missile generation probability and turbine casing impact models developed in Ref. [2]; (2) development of a methodology for the prediction of the motion of the postulated missile fragments that perforate the turbine casing; (3) development of a model using the experimental impact data to predict the effects of fragment impact on nuclear power plant barriers and components; (4) construction of a probabilistic damage assessment methodology using Monte Carlo simulation methodology; and (5) implementation of the methodology into an independent computer program (TURMIS), demonstration of its application to an example case study problem, and assessment of prediction sensitivity. (orig./RW)

  11. Missile non-proliferation: an alternative approach

    International Nuclear Information System (INIS)

    Delory, Stephane

    2011-01-01

    In this report, the author first proposes an overview of the notion of missile prohibition. He notices that the association between weapons of mass destruction and missiles is a prelude to the legitimacy of missile control, notably within the framework of the Missile Technology Control Regime or MTCR. He also comments the notion of total ban. In a second part, the author analyses and discusses the limitations of the control of technology diffusion. He discusses the role of the MTCR, comments the evolution of this regime with the taking of China and Russia into consideration, the impacts of national implementations of export regimes on the MTCR, and economic aspects of control implementation. In the next part, the author addresses other kinds of limitations, i.e. those related with capacity evolutions of proliferating States. The last part addresses the evolution towards a new definition of approach to missile non-proliferation, notably in terms of perception of missile roles and of technology transfer controls

  12. Veiled Normalization: The Implications of Japanese Missile Defense

    Science.gov (United States)

    2008-09-01

    1 Mindy Kotler and Daisuke Okuyama. “Japan’s Global Ambivalence.” Foreign Policy, no. 130, (2002): 96-97. 19...risk in entering the arms market .93 (2006) Self Defense Law 82-2 : In 2006, a significant m ilestone was made in regards to the delegation of...Information Gathering Satellite (IGS) System." Intelligence and National Security 19, no. 3 (Autumn, 2004). Kotler , Mindy and Daisuke Okuyama

  13. Killing tensors and conformal Killing tensors from conformal Killing vectors

    International Nuclear Information System (INIS)

    Rani, Raffaele; Edgar, S Brian; Barnes, Alan

    2003-01-01

    Koutras has proposed some methods to construct reducible proper conformal Killing tensors and Killing tensors (which are, in general, irreducible) when a pair of orthogonal conformal Killing vectors exist in a given space. We give the completely general result demonstrating that this severe restriction of orthogonality is unnecessary. In addition, we correct and extend some results concerning Killing tensors constructed from a single conformal Killing vector. A number of examples demonstrate that it is possible to construct a much larger class of reducible proper conformal Killing tensors and Killing tensors than permitted by the Koutras algorithms. In particular, by showing that all conformal Killing tensors are reducible in conformally flat spaces, we have a method of constructing all conformal Killing tensors, and hence all the Killing tensors (which will in general be irreducible) of conformally flat spaces using their conformal Killing vectors

  14. 77 FR 51970 - Renewal of Missile Defense Advisory Committee

    Science.gov (United States)

    2012-08-28

    ... limitation also applies to any DoD authorized subcommittees. The Secretary of Defense, based upon the... required to be in attendance at all Committee and subcommittee meetings for the entire duration of each and... Designated Federal Officer shall attend the entire duration of the Committee or subcommittee meeting. The...

  15. An Investigation of the Combat Air Patrol Stationing in an Integrated Air Defense Scenario

    Science.gov (United States)

    1990-12-01

    guided missiles, drones , decoys and short range missiles and bombs. The defensive elements include a C2 netting of early warning (EW), ground...M, 69 andar 70045 Brasilia, DF Brasil 6. Departamento de Ensino Da Aerondutica Av. Mal CAmara , 233, 10 andar 20020 Rio de Janeiro, RJ Brasil 7...Diretoria de Informdtica e Estatfstica da Aeron~utica Av. Mal CAmara , 233, 8Q andar 20020 Rio de Janeiro, RJ Brasil 11. Centro de Computagdo da Aeronutica-BR

  16. Historical development of world wide guided missiles

    Science.gov (United States)

    Spearman, M. L.

    1978-01-01

    This paper attempts to put in perspective the development of missiles from early history to present time. The influence of World War II in accelerating the development of guided missiles, particularly through German scientists, is discussed. The dispersion of German scientists to other countries and the coupling of their work with native talent to develop guided missiles is traced. Particular emphasis is placed on the evolution of the missile in the U.S. and the U.S.S.R. Since the Soviets possess what is probably the world's most complete array of dedicated missile system types, their known inventory is reviewed in some detail.

  17. Inherently Offensive: Airpower and the Dialectic with Defense

    Science.gov (United States)

    2017-06-01

    detailed definition up front. Ted Hopf, writing in The American Political Science Review, argues, “the offense-defense balance consists of three elements...technology contributed to air power’s ability to maintain overwhelming offensive 12 Hopf, Ted . "Polarity...fighters and surface-to-air missile systems. John Patterson explains why this is true, “most fighter aircraft operate in the X - and Ku-bands because

  18. Effects of Experimental Volleyball Rules Quantified by Type and Number of Jumps, Hits and Contacts

    Directory of Open Access Journals (Sweden)

    Mladen Stankovic

    2017-10-01

    Full Text Available The purpose of this study was to determine the influence of the two new rules tested at the inaugural U23 Men’s Volleyball World Championship (21-point set excluding the fifth set, and 15 seconds between rallies–10 seconds from the finished point until the referee’s whistle for serve and five seconds for performing the serve on number and types of jumps and number of contacts and hits. The analysis comprised 25,930 jumps (an essential physical activity for volleyball, 15,706 contacts and 10,224 hits during 36 matches played by 144 males aged under 23 at the first Under 23 Men’s World Championships organized in Uberlandia, Brazil, in 2013. Two investigations were conducted: 1 Analysis of jumps by Jump type, In-game role and Level of set win; 2 Analysis of contacts (reception, setting, block, defense and hits (serve and attack by Type, In-game role and Set outcome. Significant differences (p=0.000 were found between in-game role and jump type, as Middle blocker performed the most (34.7%, followed by Outside hitter (24.9%, Setter (24.6% and Opposite (15.8%. Significant differences were found for number and types of Hits between set Winner and Loser teams only for serves by Setter (p<0.001 and Middle blocker (p<0.05. The results showed major differences in jumps, hits and contacts between in-game roles: Middle blocker was the most frequent jumping position, followed by Outside hitter and Setter. The Libero showed a new tendency of being Setter with a jump after the initial Setter defense.

  19. The Iraqi Ballistic Missile Program: The Gulf War and the Future of the Missile Threat.

    Science.gov (United States)

    1992-06-01

    London, 1985. In Antwerp an even worse event occurred on December 16, 1944 when a V-2 struck the Rex Cinema killing 271. See David Irving, The Mare’s...Husayn mis- 3. Produced in North Korea, the Scud-PIP is an improved version of the Scud-B. Joseph S. Bermudez Jr., "Syria’s Acquisition of North Korean ...34Critics Rap N. Korean Sincerity," Defense News, April 13-19,1992, p. 36. r3oTkom?s B-C°chran» William M. Arkin, Milton M. Hoenjg, Nuclear Weapons

  20. Defense Acquisitions: Missile Defense Acquisition Strategy Generates Results but Delivers Less at a Higher Cost

    National Research Council Canada - National Science Library

    2007-01-01

    .... For example, the Ground-based Midcourse Defense (GMD) element successfully conducted its first end-to-end test of one engagement scenario, the element s first successful intercept test since 2002...

  1. 42 CFR 495.344 - Approval of the State Medicaid HIT plan, the HIT PAPD and update, the HIT IAPD and update, and...

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Approval of the State Medicaid HIT plan, the HIT PAPD and update, the HIT IAPD and update, and the annual HIT IAPD. 495.344 Section 495.344 Public... Requirements Specific to the Medicaid Program § 495.344 Approval of the State Medicaid HIT plan, the HIT PAPD...

  2. Increased Range/Mini-Cruise Missile

    National Research Council Canada - National Science Library

    2006-01-01

    Technical Directions Inc. (TDI), Ortonville, Michigan, was asked by the U.S. Army and the U.S. Air Force to improve the efficiency of their J-45 missile engine for the NLOS-LS LAM Loitering Attack Missile...

  3. Killing of trypanosomatid parasites by a modified bovine host defense peptide, BMAP-18.

    Directory of Open Access Journals (Sweden)

    Lee R Haines

    Full Text Available BACKGROUND: Tropical diseases caused by parasites continue to cause socioeconomic devastation that reverberates worldwide. There is a growing need for new control measures for many of these diseases due to increasing drug resistance exhibited by the parasites and problems with drug toxicity. One new approach is to apply host defense peptides (HDP; formerly called antimicrobial peptides to disease control, either to treat infected hosts, or to prevent disease transmission by interfering with parasites in their insect vectors. A potent anti-parasite effector is bovine myeloid antimicrobial peptide-27 (BMAP-27, a member of the cathelicidin family. Although BMAP-27 is a potent inhibitor of microbial growth, at higher concentrations it also exhibits cytotoxicity to mammalian cells. We tested the anti-parasite activity of BMAP-18, a truncated peptide that lacks the hydrophobic C-terminal sequence of the BMAP-27 parent molecule, an alteration that confers reduced toxicity to mammalian cells. METHODOLOGY/PRINCIPAL FINDINGS: BMAP-18 showed strong growth inhibitory activity against several species and life cycle stages of African trypanosomes, fish trypanosomes and Leishmania parasites in vitro. When compared to native BMAP-27, the truncated BMAP-18 peptide showed reduced cytotoxicity on a wide variety of mammalian and insect cells and on Sodalis glossindius, a bacterial symbiont of the tsetse vector. The fluorescent stain rhodamine 123 was used in immunofluorescence microscopy and flow cytometry experiments to show that BMAP-18 at low concentrations rapidly disrupted mitochondrial potential without obvious alteration of parasite plasma membranes, thus inducing death by apoptosis. Scanning electron microscopy revealed that higher concentrations of BMAP-18 induced membrane lesions in the parasites as early as 15 minutes after exposure, thus killing them by necrosis. In addition to direct killing of parasites, BMAP-18 was shown to inhibit LPS

  4. Probability and containment of turbine missiles

    International Nuclear Information System (INIS)

    Yeh, G.C.K.

    1976-01-01

    With the trend toward ever larger power generating plants with large high-speed turbines, an important plant design consideration is the potential for and consequences of mechanical failure of turbine rotors. Such rotor failure could result in high-velocity disc fragments (turbine missiles) perforating the turbine casing and jeopardizing vital plant systems. The designer must first estimate the probability of any turbine missile damaging any safety-related plant component for his turbine and his plant arrangement. If the probability is not low enough to be acceptable to the regulatory agency, he must design a shield to contain the postulated turbine missiles. Alternatively, the shield could be designed to retard (to reduce the velocity of) the missiles such that they would not damage any vital plant system. In this paper, some of the presently available references that can be used to evaluate the probability, containment and retardation of turbine missiles are reviewed; various alternative methods are compared; and subjects for future research are recommended. (Auth.)

  5. The assessment of tornado missile hazard to nuclear power plants

    International Nuclear Information System (INIS)

    Goodman, J.; Koch, J.E.

    1983-01-01

    Numerical methods and computer codes for assessing tornado missile hazards to nuclear power plants are developed. Due to the uncertainty and randomness of tornado and tornado-generated missiles' characteristics, the damage probability of targets has a highly spread distribution. The proposed method is useful for assessing the risk of not providing protection to some nonsafety-related targets whose failure can create a hazard to the safe operation of nuclear power plants

  6. Targeted killing with drones? Old arguments, new technologies

    Directory of Open Access Journals (Sweden)

    Meisels Tamar

    2018-01-01

    Full Text Available The question of how to contend with terrorism in keeping with our preexisting moral and legal commitments now challenges Europe as well as Israel and the United States: how do we apply Just War Theory and International Law to asymmetrical warfare, specifically to our counter terrorism measures? What can the classic moral argument in Just and Unjust Wars teach us about contemporary targeted killings with drones? I begin with a defense of targeted killing, arguing for the advantages of pin pointed attacks over any alternative measure available for combatting terrorism. Assuming the legitimacy of killing combatants in wartime, I argue, there is nothing wrong, and in fact much that is right, with targeting particular terrorists selected by name, as long as their assassinations can be reasonably expected to reduce terrorist hostilities rather than increase it. Subsequently, I offer some further thoughts and comments on the use of remotely piloted aircrafts to carry out targeted killings, and address the various sources for discomfort with this practice identified by Michael Walzer and others.

  7. Tornado missile impact study

    International Nuclear Information System (INIS)

    McDonald, J.R.

    1991-01-01

    UCRL-15910 specifies wind and tornado missiles for moderate- and high-hazard DOE facilities. Wall-barrier specimens have been tested at the Tornado Missile Impact Facility at Texas Tech University. The facility has an air-activated tornado missile cannon capable of firing 2x4 timber planks weighing 12 lb at speeds up to 150 mph and 3-in-diameter steel pipes weighing 75 lb at speeds to 7 5 mph. Wall barriers tested to date include reinforced concrete walls from 4-in. to 10-in. thick; 8-in. and 12-in. walls of reinforced concrete masonry units (CMU); two other masonry wall configurations consisting of an 8-in. CMU with a 4-in. clay-brick veneer and a 10-in. composite wall with two wythes of 4-in. clay brick. The impact test series is designed to determine the impact speed that will produce backface spall of each wall barrier. A set of 15 wall sections has been constructed and tested at this time. Preliminary finding suggest that all cells of CMU walls must be grouted to prevent missile penetration. Walls recommended in the workshop on UCRL-15910 provide acceptable protection if cracking can be accepted

  8. Local impact effects on concrete target due to missile: An empirical and numerical approach

    International Nuclear Information System (INIS)

    Ranjan, Rajiv; Banerjee, Sauvik; Singh, R.K.; Banerji, Pradipta

    2014-01-01

    Highlights: • Local impact effect of hard missile on reinforced concrete targets has been studied. • Review of empirical formulation for predicting local response carried out. • Numerical simulation of experimental test of Kojima (1991) carried out. • Divergence of FE results with those obtained using emperical formulations. • Close match of numerical simulation results with experimental data. - Abstract: Concrete containment walls and internal concrete barrier walls of a Nuclear Power Plant safety related structures are often required to be designed for externally and internally generated missiles. Potential missiles include external extreme wind generated missiles, aircraft crash and internal accident generated missiles such as impact due to turbine blade failure and steel pipe missiles resulting from pipe break. The objective of the present paper is to compare local missile impact effects on reinforced concrete target using available empirical formulations with those obtained using LS-DYNA numerical simulation. The use of numerical simulations for capturing the transient structural response has become increasingly used for structural design against impact loads. They overcome the limits of applicability of the empirical formulae and also provide information on stress and deformation fields, which may be used to improve the resistance of the concrete. Finite element (FE) analyses of an experimental impact problem reported by Kojima (1991) are carried out that are able to capture the missile impact effects; in terms of local and global damage. The continuous surface cap model has been used for modelling concrete behaviour. A range of missile velocity has been considered to simulate local missile impact phenomenon and modes of failure and to capture the concrete response from elastic to plastic fracture. A comparison is then made between the empirical formulations, numerical simulation results, and available experimental results of slab impact tests

  9. Tornado missile simulation and risk analysis

    International Nuclear Information System (INIS)

    Twisdale, L.A.; Dunn, W.L.; Chu, J.

    1978-01-01

    Mathematical models of the contributing events to the tornado missile hazard at nuclear power plants have been developed in which the major sources of uncertainty have been considered in a probabilistic framework. These models have been structured into a sequential event formalism which permits the treatment of both single and multiple missile generation events. A simulation computer code utilizing these models has been developed to obtain estimates of tornado missile event likelihoods. Two case studies have been analyzed; the results indicate that the probability of a single missile from the sampling population impacting any of the plant's targets is less then about 10 -7 per reactor-year. Additional work is needed for verification and sensitivity study

  10. Introducing the RadBioStat Educational Software: Computer-Assisted Teaching of the Random Nature of Cell Killing

    Directory of Open Access Journals (Sweden)

    Safari A

    2014-06-01

    Full Text Available The interaction of radiation with cells and tissues has a random nature. Therefore, understanding the random nature of cell killing that is determined by Poisson distribution statistics is an essential point in education of radiation biology. RadBioStat is a newly developed educational MATLAB-based software designed for computer-assisted learning of the target theory in radiation biology. Although its potential applications is developing rapidly, currently RadBioStat software can be a useful tool in computerassisted education of radiobiological models such as single target single hit, multiple target single hit and multiple target multiple hit. Scholars’ feedback is valuable to the producers of this software and help them continuously improve this product, add new features and increase its desirability and functionality.

  11. Bodies with noncircular cross sections and bank-to-turn missiles

    Science.gov (United States)

    Jackson, C. M., Jr.; Sawyer, W. C.

    1992-01-01

    A development status evaluation is presented for the aerodynamics of missile configurations with noncircular cross-sections and bank-to-turn maneuvering systems, giving attention to cases with elliptical and square cross-sections, as well as bodies with variable cross-sections. The assessment of bank-to-turn missile performance notes inherent stability/control problems. A summary and index are provided for aerodynamic data on monoplanar configurations, including those which incorporate airbreathing propulsion systems.

  12. Human Neutrophils Use Different Mechanisms To Kill Aspergillus fumigatus Conidia and Hyphae: Evidence from Phagocyte Defects.

    Science.gov (United States)

    Gazendam, Roel P; van Hamme, John L; Tool, Anton T J; Hoogenboezem, Mark; van den Berg, J Merlijn; Prins, Jan M; Vitkov, Ljubomir; van de Veerdonk, Frank L; van den Berg, Timo K; Roos, Dirk; Kuijpers, Taco W

    2016-02-01

    Neutrophils are known to play a pivotal role in the host defense against Aspergillus infections. This is illustrated by the prevalence of Aspergillus infections in patients with neutropenia or phagocyte functional defects, such as chronic granulomatous disease. However, the mechanisms by which human neutrophils recognize and kill Aspergillus are poorly understood. In this work, we have studied in detail which neutrophil functions, including neutrophil extracellular trap (NET) formation, are involved in the killing of Aspergillus fumigatus conidia and hyphae, using neutrophils from patients with well-defined genetic immunodeficiencies. Recognition of conidia involves integrin CD11b/CD18 (and not dectin-1), which triggers a PI3K-dependent nonoxidative intracellular mechanism of killing. When the conidia escape from early killing and germinate, the extracellular destruction of the Aspergillus hyphae needs opsonization by Abs and involves predominantly recognition via Fcγ receptors, signaling via Syk, PI3K, and protein kinase C to trigger the production of toxic reactive oxygen metabolites by the NADPH oxidase and myeloperoxidase. A. fumigatus induces NET formation; however, NETs did not contribute to A. fumigatus killing. Thus, our findings reveal distinct killing mechanisms of Aspergillus conidia and hyphae by human neutrophils, leading to a comprehensive insight in the innate antifungal response. Copyright © 2016 by The American Association of Immunologists, Inc.

  13. Modulation of pulmonary defense mechanisms by acute exposures to nitrogen dioxide. [Staphylococcus aureus; Proteus mirabilis; Pasteurella pneumotropica

    Energy Technology Data Exchange (ETDEWEB)

    Jakab, G.J.

    1987-02-01

    The effect of acute exposures to NO/sub 2/ on the antibacterial defenses of the murine lung was assessed following inhalation challenges with Staphylococcus aureus, Proteus mirabilis, and Pasteurella pneumotropica. With S. aureus pulmonary antibacterial defenses were suppressed at NO/sub 2/ levels of 4.0 ppm and greater. Exposure to 10.0 ppm enhanced the intrapulmonary killing of P. mirabilis which correlated with an increase in the phagocytic cell populations lavaged from the lungs; at 20.0 ppm bactericidal activity against P. mirabilis was impaired. Pulmonary antibacterial defenses against P. pneumotropica were impaired at 10.0 ppm which correlated with a decrease in the retrieved phagocytic lung cell population. Reversing the order of treatment (ie., NO/sub 2/ exposure prior to bacterial challenge) raised the threshold concentration for NO/sub 2/-induced impairment of intrapulmonary bacterial killing. With S. aureus the effect was not observed at 5.0 ppm but at 10.0 ppm and with P. mirabilis not at 20.0 ppm but at 30.0 ppm intrapulmonary killing was enhanced. Exposures up to 20.0 ppm of NO/sub 2/ did not effect the physical translocation mechanisms of the lung as quantitated by declines in pulmonary radiotracer activity following aerogenic challenge with /sup 32/P-labeled staphylococci.

  14. An analysis on the impact of the 1972 ABM Treaty and its affect on the procurement of a National Missile Defense System

    OpenAIRE

    McDaniel, Donald B.

    2002-01-01

    Approved for public release; distribution is unlimited For the last thirty years, many strategists have considered the 1972 Anti-ballistic Missile (ABM) Treaty as the foundation for arms control. Others have insisted that its existence perpetuates American vulnerability to a ballistic missile attack. Since its inception, the ABM Treaty has been amended only once, but the geopolitical structure of the world has changed dramatically. The Cold War has ended and many new threats have emerged. ...

  15. A review of electromagnetic missiles

    International Nuclear Information System (INIS)

    Wu, T.T.; Shen, H.M.; Myers, J.M.

    1988-01-01

    Theoretical results are reviewed pertaining to the behavior of transient electromagnetic fields in the limit of great distances from their sources. In 1985 it was shown that pulses of finite total radiated energy could propagate to a distant receiver, delivering energy that decreases much more slowly than the usual r - 2 . Such pulses have been referred to as electromagnetic (EM) missiles. The types first discovered propagate along a straight line with a monotonically (though slowly) decreasing time-integrated flux. Other types are now known. One type can be made to rise and fall with increasing distance; another is the curved EM missile. Early efforts to classify EM missiles are reviewed

  16. Protivoklopni vođeni projektili zapadne Evrope, Izraela i Indije / Anti-tank guided missiles of western Europe, Israel and India

    Directory of Open Access Journals (Sweden)

    Goran M. Lazić

    2010-10-01

    Full Text Available Protivoklopni vođeni projektili namenjeni su za uništavanje teško-oklopljenih tenkova, kao i drugih oklopnih vozila. Ovaj rad nudi istorijsko-tehnički pregled (razvoj projektila kroz generacije i osnovni podaci vezani za borbeno-operativno dejstvo ovih projektila ovog tipa naoružanja koje poseduju zemlje zapadne Evrope, Izraela i Indije. Pored osnovnih podataka navode se i cene nekih projektila ponaosob, kao i tendencije razvoja u ovoj grani naoružanja. / Anti-tank guided missiles are designed to hit and destroy heavily armored tanks and other armored fighting vehicles. This review offers a historical and technical overview (development of missiles throughout generations and basic data about combat and operational actions of this type of weapons in Western Europe, Israel and India. The review also offers prices of some missiles and tendencies of development in this branch. Anti-tank guided missiles are primarily designed to destroy armoured tanks as well as other armoured vehicles. Anti-tank guided systems differ in size, from small ones (shoulder-launched missile weapons carried by a single person to complex weapon systems (crewserved, vehicle-mounted and airborne systems. The first generation of anti-tank guided missiles is a manually guided MCLOS (Manual Command to Line of Sight projectile requiring an operator to guide and steer it to a target by a joystick. Vickers vigilant is a British anti-tank wire-guided missile, produced in 1956. The Bantam (Bofors Anti-Tank Missile or Robot 53 (RB 53 is a Swedish anti-tank wire-guided missile, produced in 1963. Cobra is a German - Swiss product which entered the operational use in 1956. It was replaced by Cobra 2000 and Mamaba systems, which are anti-tank guided missiles of the first generation, but with improved guidance and electronics. ENTAC (Engin téléguidé anti-char or MGM Petronor-32A is a French anti-tank wire-guided missile, widely spread and still in the operational use in many

  17. 77 FR 32639 - HIT Standards Committee and HIT Policy Committee; Call for Nominations

    Science.gov (United States)

    2012-06-01

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee and HIT Policy Committee; Call for... Health Information Technology Policy Committee (HITPC). Name of Committees: HIT Standards Committee and HIT Policy Committee. General Function of the Committees: The HITSC is charged to provide...

  18. NIMROD Simulations of the HIT-SI and HIT-SI3 Devices

    Science.gov (United States)

    Morgan, Kyle; Jarboe, Tom; Hossack, Aaron; Chandra, Rian; Everson, Chris

    2017-10-01

    The Helicity Injected Torus with Steady Inductive helicity injection (HIT-SI) experiment uses a set of inductively driven helicity injectors to apply non-axisymmetric current drive on the edge of the plasma, driving an axisymmetric spheromak equilibrium in a central confinement volume. Significant improvements have been made to extended MHD modeling of HIT-SI, with both the resolution of disagreement at high injector frequencies in HIT-SI in addition to successes with the new upgraded HIT-SI3 device. Previous numerical studies of HIT-SI, using a zero-beta eMHD model, focused on operations with a drive frequency of 14.5 kHz, and found reduced agreement with both the magnetic profile and current amplification at higher frequencies (30-70 kHz). HIT-SI3 has three helicity injectors which are able to operate with different mode structures of perturbations through the different relative temporal phasing of the injectors. Simulations that allow for pressure gradients have been performed in the parameter regimes of both devices using the NIMROD code and show improved agreement with experimental results, most notably capturing the observed Shafranov-shift due to increased beta observed at higher finj in HIT-SI and the variety of toroidal perturbation spectra available in HIT-SI3. This material is based upon work supported by the U.S. Department of Energy, Office of Science, Office of Fusion Energy Sciences under Award Number DE-FG02- 96ER54361.

  19. Turbine-missile casing exit tests

    International Nuclear Information System (INIS)

    Yoshimura, H.R.; Sliter, G.E.

    1978-01-01

    Nuclear power plant designers are required to provide safety-related components with adequate protection against hypothetical turbine-missile impacts. In plants with a ''peninsula'' arrangement, protection is provided by installing the turbine axis radially from the reactor building, so that potential missile trajectories are not in line with the plant. In plants with a ''non-peninsula'' arrangement (turbine axis perpendicular to a radius), designers rely on the low probability of a missile strike and on the protection provided by reinforced concrete walls in order to demonstrate an adequate level of protection USNRC Regulatory Guide 1.115). One of the critical first steps in demonstrating adequacy is the determination of the energy and spin of the turbine segments as they exit the turbine casing. The spin increases the probability that a subsequent impact with a protective barrier will be off-normal and therefore less severe than the normal impact assumed in plant designs. Two full-scale turbine-missile casing exit tests which were conducted by Sandia Laboratories at their rocket-sled facility in Albuquerque, New Mexico, are described. Because of wide variations in turbine design details, postulated failure conditions, and missile exit scenarios, the conditions for the two tests were carefully selected to be as prototypical as possible, while still maintaining the well-controlled and well-characterized test conditions needed for generating benchmark data

  20. Inspector General, Department of Defense, Semiannual Report to the Congress, April 1, 2010 - September 30, 2010

    Science.gov (United States)

    2010-10-01

    Centers 06/21/2010 USAAA A-2010-0121-ALO Real Property Sustainment, Restoration, and Modernization 06/25/2010 USAAA A-2010-0124- FFM Review of Port...Supply Enhanced System, Project Manager, 07/07/2010 Cruise Missile Defense System USAAA A-2010-0131- FFM Agreed-Upon Procedures Attestation of Audit... FFM Follow-up Audit of FY 05 Subsistence Charges 07/29/2010 USAAA A-2010-0144-ALR Follow-up Audit of Property Accountability, Oklahoma Army National

  1. Aerodynamic Performance Predictions of a SA- 2 Missile Using Missile DATCOM

    Science.gov (United States)

    2009-09-01

    transformation that is given by Eqs. (4) and (5). Eqs. (8)–(10) show the formulation in the body and wind axis terminology. 2,0D AC C kC   L (8) 10 cos...by Teo (2008) using Missile LAB code. However, the missile geometry then was set up from a rudimentary drawing and not one that represented a high...provided by MSIC. These particular cases were run forcing turbulent flow with a surface roughness of 0.001016 cm, which was found by Teo (2008) to

  2. Probabilistic methodology for turbine missile risk analysis

    International Nuclear Information System (INIS)

    Twisdale, L.A.; Dunn, W.L.; Frank, R.A.

    1984-01-01

    A methodology has been developed for estimation of the probabilities of turbine-generated missile damage to nuclear power plant structures and systems. Mathematical models of the missile generation, transport, and impact events have been developed and sequenced to form an integrated turbine missile simulation methodology. Probabilistic Monte Carlo techniques are used to estimate the plant impact and damage probabilities. The methodology has been coded in the TURMIS computer code to facilitate numerical analysis and plant-specific turbine missile probability assessments. Sensitivity analyses have been performed on both the individual models and the integrated methodology, and probabilities have been estimated for a hypothetical nuclear power plant case study. (orig.)

  3. Aegis International and Ballistic Missile Defense: A New Interoperability Network

    Science.gov (United States)

    2011-06-01

    the 1950’s and 1960s ( NIKE Hercules, Sentinel, Safeguard, Site Defense, etc.). The objectives have been pursued by a centralized organization (the...from land. This means greater geographic flexibility, greater survivability and greater scalability in response to an evolving threat. That’s

  4. Rare transformation to double hit lymphoma in Waldenstrom's macroglobulinemia.

    Science.gov (United States)

    Okolo, Onyemaechi N; Johnson, Ariel C; Yun, Seongseok; Arnold, Stacy J; Anwer, Faiz

    2017-08-01

    Waldenström macroglobulinemia (WM) is a lymphoproliferative lymphoma that is characterized by monoclonal immunoglobulin M (IgM) protein and bone marrow infiltration. Its incidence is rare and rarer still is its ability to transform to a B-cell lymphoma, particularly the aggressive diffuse large B-cell lymphoma, which bodes a poor prognosis. When transformation includes mutations of MYC, BCL-2 and/or BCL-6, it is known as a 'double hit' or 'triple hit' lymphoma respectively. This paper presents a rare case of WM with mutations positive for MYC and BCL2, making it a case of double hit B-cell lymphoplasmacytic lymphoma with plasmatic differentiation without morphological transformation to aggressive histology like DLBCL. The paper also broadens to include discussions on current topics in the classification, diagnosis, possible causes of transformation, and treatment of WM, including transformation to double hit lymphoma. The significance of this case lies in that the presence of double hit lymphoma-like genetic mutations in WM have not been previously described in the literature and potentially such changes are harbinger of extra-nodal presentation, aggressive growth, and possibly poor prognosis, if data from other double-hit lymphoma are extrapolated.

  5. IR sensor design insight from missile-plume prediction models

    Science.gov (United States)

    Rapanotti, John L.; Gilbert, Bruno; Richer, Guy; Stowe, Robert

    2002-08-01

    Modern anti-tank missiles and the requirement of rapid deployment have significantly reduced the use of passive armour in protecting land vehicles. Vehicle survivability is becoming more dependent on sensors, computers and countermeasures to detect and avoid threats. An analysis of missile propellants suggests that missile detection based on plume characteristics alone may be more difficult than anticipated. Currently, the passive detection of missiles depends on signatures with a significant ultraviolet component. This approach is effective in detecting anti-aircraft missiles that rely on powerful motors to pursue high-speed aircraft. The high temperature exhaust from these missiles contains significant levels of carbon dioxide, water and, often, metal oxides such as alumina. The plumes emits strongest in the infrared, 1 to 5micrometers , regions with a significant component of the signature extending into the ultraviolet domain. Many anti-tank missiles do not need the same level of propulsion and radiate significantly less. These low velocity missiles, relying on the destructive force of shaped-charge warhead, are more difficult to detect. There is virtually no ultraviolet component and detection based on UV sensors is impractical. The transition in missile detection from UV to IR is reasonable, based on trends in imaging technology, but from the analysis presented in this paper even IR imagers may have difficulty in detecting missile plumes. This suggests that the emphasis should be placed in the detection of the missile hard body in the longer wavelengths of 8 to 12micrometers . The analysis described in this paper is based on solution of the governing equations of plume physics and chemistry. These models will be used to develop better sensors and threat detection algorithms.

  6. The BMD threat: when and how to intercept - Opinion

    NARCIS (Netherlands)

    Bouquet, F.

    2007-01-01

    NATO and the US are involved in developing Ballistic missile defense (BMD) capabilities that must provide protection against various threats, which has received global attention. One needs to carefully consider the consequences of employing the defensive missiles. It is assumed that there will be no

  7. Lead generation and examples opinion regarding how to follow up hits.

    Science.gov (United States)

    Orita, Masaya; Ohno, Kazuki; Warizaya, Masaichi; Amano, Yasushi; Niimi, Tatsuya

    2011-01-01

    In fragment-based drug discovery (FBDD), not only identifying the starting fragment hit to be developed but also generating a drug lead from that starting fragment hit is important. Converting fragment hits to leads is generally similar to a high-throughput screening (HTS) hits-to-leads approach in that properties associated with activity for a target protein, such as selectivity against other targets and absorption, distribution, metabolism, excretion, and toxicity (ADME/Tox), and physicochemical properties should be taken into account. However, enhancing the potency of the fragment hit is a key requirement in FBDD, unlike HTS, because initial fragment hits are generally weak. This enhancement is presently achieved by adding additional chemical groups which bind to additional parts of the target protein or by joining or combining two or more hit fragments; however, strategies for effecting greater improvements in effective activity are needed. X-ray analysis is a key technology attractive for converting fragments to drug leads. This method makes it clear whether a fragment hit can act as an anchor and provides insight regarding introduction of functional groups to improve fragment activity. Data on follow-up chemical synthesis of fragment hits has allowed for the differentiation of four different strategies: fragment optimization, fragment linking, fragment self-assembly, and fragment evolution. Here, we discuss our opinion regarding how to follow up on fragment hits, with a focus on the importance of fragment hits as an anchor moiety to so-called hot spots in the target protein using crystallographic data. Copyright © 2011 Elsevier Inc. All rights reserved.

  8. Guidance Law and Neural Control for Hypersonic Missile to Track Targets

    Directory of Open Access Journals (Sweden)

    Wenxing Fu

    2016-01-01

    Full Text Available Hypersonic technology plays an important role in prompt global strike. Because the flight dynamics of a hypersonic vehicle is nonlinear, uncertain, and highly coupled, the controller design is challenging, especially to design its guidance and control law during the attack of a maneuvering target. In this paper, the sliding mode control (SMC method is used to develop the guidance law from which the desired flight path angle is derived. With the desired information as control command, the adaptive neural control in discrete time is investigated ingeniously for the longitudinal dynamics of the hypersonic missile. The proposed guidance and control laws are validated by simulation of a hypersonic missile against a maneuvering target. It is demonstrated that the scheme has good robustness and high accuracy to attack a maneuvering target in the presence of external disturbance and missile model uncertainty.

  9. The Cooperative Ballistic Missile Defence Game

    NARCIS (Netherlands)

    Evers, L.; Barros, A.I.; Monsuur, H.

    2013-01-01

    The increasing proliferation of ballistic missiles and weapons of mass destruction poses new risks worldwide. For a threatened nation and given the characteristics of this threat a layered ballistic missile defence system strategy appears to be the preferred solution. However, such a strategy

  10. Eyewitness Identification Reforms: Are Suggestiveness-Induced Hits and Guesses True Hits?

    Science.gov (United States)

    Wells, Gary L; Steblay, Nancy K; Dysart, Jennifer E

    2012-05-01

    Research-based reforms for collecting eyewitness identification evidence (e.g., unbiased pre-lineup instructions, double-blind administration) have been proposed by psychologists and adopted in increasing numbers of jurisdictions across the United States. It is well known that reducing rates of mistaken identifications can also reduce accurate identification rates (hits). But the reforms are largely designed to reduce the suggestiveness of the procedures they are meant to replace. Accordingly, we argue that it is misleading to label any hits obtained because of suggestive procedures as "hits" and then saddle reforms with the charge that they reduce the rate of these illegitimate hits. Eyewitness identification evidence should be based solely on the independent memory of the witness, not aided by biased instructions, cues from lineup administrators, or the use of lineup fillers who make the suspect stand out. Failure to call out these hits as being illegitimate can give solace to those who are motivated to preserve the status quo. © The Author(s) 2012.

  11. Post-hit dynamics of price limit hits in the Chinese stock markets

    Science.gov (United States)

    Wu, Ting; Wang, Yue; Li, Ming-Xia

    2017-01-01

    Price limit trading rules are useful to cool off traders short-term trading mania on individual stocks. The price dynamics approaching the limit boards are known as the magnet effect. However, the price dynamics after opening price limit hits are not well investigated. Here, we provide a detailed analysis on the price dynamics after the hits of up-limit or down-limit is open based on all A-share stocks traded in the Chinese stock markets. A "W" shape is found in the expected return, which reveals high probability of a continuous price limit hit on the following day. We also find that price dynamics after opening limit hits are dependent on the market trends. The time span of continuously hitting the price limit is found to an influence factor of the expected profit after the limit hit is open. Our analysis provides a better understanding of the price dynamics around the limit boards and contributes potential practical values for investors.

  12. Pipe missile impact experiments on concrete models

    International Nuclear Information System (INIS)

    McHugh, S.; Gupta, Y.; Seaman, L.

    1981-06-01

    The experiments described in this study are a part of SRI studies for EPRI on the local response of reinforced concrete panels to missile impacts. The objectives of this task were to determine the feasibility of using scale model tests to reproduce the impact response of reinforced concrete panels observed in full-scale tests with pipe missiles and to evaluate the effect of concrete strength on the impact response. The experimental approach consisted of replica scaling: the missile and target materials were similar to those used in the full-scale tests, with all dimensions scaled by 5/32. Four criteria were selected for comparing the scaled and full-scale test results: frontface penetration, backface scabbing threshold, internal cracking in the panel, and missile deformation

  13. Prevention of heavy missiles during severe PWR accidents

    International Nuclear Information System (INIS)

    Krieg, R.

    1994-01-01

    For future pressurized water reactors, which should be designed against core melt down accidents, missiles generated inside the containment present a severe problem for its integrity. The masses and geometries of the missiles as well as their velocities may vary to a great extend. Therefore, a reliable proof of the containment integrity is very difficult. To overcome this problem the potential sources of missiles are discussed. In section 5 it is concluded that the generation of heavy missiles must be prevented. Steam explosions must not damage the reactor vessel head. Thus fragments of the head cannot become missiles endangering the containment shell. Furthermore, during a melt-through failure of the reactor vessel under high pressure the resulting forces must not catapult the whole vessel against the containment shell. Only missiles caused by hydrogen explosions might be tolerable, but shielding structures which protect the containment shell might be required. Here further investigations are necessary. Finally, measures are described showing that the generation of heavy missiles can indeed be prevented. In section 6 investigations are explained which will confirm the strength of the reactor vessel head. In section 7 a device is discussed keeping the fragments of a failing reactor vessel at its place. (author). 12 refs., 8 figs

  14. Deterrence and the Future of U.S.-GCC Defense Cooperation: A Strategic Dialogue Event

    Science.gov (United States)

    2015-07-01

    be taken to help incorporate ballistic missile defense systems into the security architecture of Gulf states. Finally, the United States should...American’s copanelist, the Kuwaiti political scientist, added that the GCC has not fully embraced the idea. “It’s an Egyptian -led project,” he said. “Cairo

  15. Senate Voting On the Strategic Defense Initiative: The Impact of the 1991 Gulf War

    Directory of Open Access Journals (Sweden)

    James F. Pasley

    2012-04-01

    Full Text Available This paper examines the effects of the success of the Patriot missile system in the 1991 Gulf War on Senate roll call votes for the Strategic Defense Initiative (SDI. Previous studies have shown that both Party Identification (PID and Ideology have had a significant effect on senators' votes on defense weapons systems. Using Logit regression techniques, this paper examines whether PID and Ideology, both of which are central to political identity, remained significant factors in three Senate votes on SDI; this paper is unique compare to previous studies of such matters in that it adds two additional explanatory variables to existing models: (1 the extent to which each state might benefit from SDI and (2 whether or not the senator from each state was up for re-election in 1992 It is hypothesized that the findings will suggest that external factors played a role in the SDI Senate votes in question. Specifically, it is hypothesized that the effects of the Gulf War Patriot missile successes led to greater legislative support (compared to support levels from previous years for the Strategic Defense Initiative among Democrats, those senators whose states would benefit from SDI funding, and those senators seeking re-election.

  16. Hit Parade

    DEFF Research Database (Denmark)

    Backe, Hans-Joachim

    2017-01-01

    Daniel Cermak-Sassenrath, Max Alexander Wrighton, Hans-Joachim Backe. Hit Parade. Installation. Kulturnatten 2017, ITU, Copenhagen, DK, Oct 13, 2017.......Daniel Cermak-Sassenrath, Max Alexander Wrighton, Hans-Joachim Backe. Hit Parade. Installation. Kulturnatten 2017, ITU, Copenhagen, DK, Oct 13, 2017....

  17. Hit Parade

    DEFF Research Database (Denmark)

    Cermak, Daniel; Wrighton, Max Alexander; Backe, Hans-Joachim

    2016-01-01

    Daniel Cermak-Sassenrath, Max Alexander Wrighton, Hans-Joachim Backe. Hit Parade. Installation. Demo Night, ITU, Copenhagen, DK, Oct 5, 2016.......Daniel Cermak-Sassenrath, Max Alexander Wrighton, Hans-Joachim Backe. Hit Parade. Installation. Demo Night, ITU, Copenhagen, DK, Oct 5, 2016....

  18. Barrier design for tornado-generated missiles

    International Nuclear Information System (INIS)

    Kar, A.K.

    1977-01-01

    Nuclear power plant facilities and many other structures need protection against missiles generated by tornados and explosions. The missile impacts result in both local and overall effects on barriers or targets. The local effects are characterized by penetration, perforation and backface spalling or scabbing of the target material. The overall effects of missile impact on structural stability are commonly evaluated in terms of the flexural and shear behaviour of the target. Empirical formulas are presented to determine the local effects on concrete and steel barriers. Procedures are given for determining the design loads for overall effects. Design methods are described. (Auth.)

  19. Barrier design for tornado-generated missiles

    International Nuclear Information System (INIS)

    Kar, A.K.

    1977-01-01

    Nuclear powerplant facilities and many other structures need protection against missiles generated by tornadoes and explosions. The missile impacts result in both local and overall effects on barriers or targets. The local effects are characterized by penetration, perforation, and backface spalling or scabbing of the target material. The overall effects of missile impact on structural stability are commonly evaluated in terms of the flexural and shear behavior of the target. Empirical formulas are presented to determine the local effects on concrete and steel barriers. Procedures are given for determining the design loads for overall effects. Design methods are described

  20. PESAN MORAL DALAM FILM TO KILL A MOCKINGBIRD (ANALISIS SEMIOTIKA PADA FILM TO KILL A MOCKINGBIRD

    OpenAIRE

    RENYOET, JAQUILINE MELISSA

    2014-01-01

    2014 JAQUILINE MELISSA RENYOET. Pesan Moral Dalam Film To Kill A Mockingbird (Analisis Semiotika Pada Film To Kill A Mockingbird). (Dibimbing oleh Muh. Nadjib dan Alem Febri Sonni). Tujuan Penelitian ini adalah mengidentifikasi bentuk pesan moral dan memahami makna pesan moral dalam film To Kill A Mockingbird. Penelitian ini dilakukan selama kurang lebih 2 bulan yaitu Maret ??? Mei 2014. Metode yang digunakan untuk penelitian ini adalah metode penelitian kualitatif den...

  1. Hit Parade

    DEFF Research Database (Denmark)

    Cermak, Daniel; Wrighton, Max Alexander; Backe, Hans-Joachim

    2016-01-01

    Daniel Cermak-Sassenrath, Max Alexander Wrighton, Hans-Joachim Backe. Hit Parade. Installation. Kulturnatten 2016, Danish Science Ministry, Copenhagen, DK, Oct 14, 2016.......Daniel Cermak-Sassenrath, Max Alexander Wrighton, Hans-Joachim Backe. Hit Parade. Installation. Kulturnatten 2016, Danish Science Ministry, Copenhagen, DK, Oct 14, 2016....

  2. Numerical simulation of tornado-borne missile impact

    International Nuclear Information System (INIS)

    Tu, D.K.; Murray, R.C.

    1977-01-01

    The feasibility of using a finite element procedure to examine the impact phenomenon of a tornado-borne missile impinging on a reinforced concrete barrier was assessed. The major emphasis of this study was to simulate the impact of a nondeformable missile. Several series of simulations were run, using an 8-in.-dia steel slug as the impacting missile. The numerical results were then compared with experimental field tests and empirical formulas. The work is in support of tornado design practices for fuel reprocessing and fuel fabrication plants

  3. Nuclear Targeting Terms for Engineers and Scientists

    Energy Technology Data Exchange (ETDEWEB)

    St Ledger, John W. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-02-01

    The Department of Defense has a methodology for targeting nuclear weapons, and a jargon that is used to communicate between the analysts, planners, aircrews, and missile crews. The typical engineer or scientist in the Department of Energy may not have been exposed to the nuclear weapons targeting terms and methods. This report provides an introduction to the terms and methodologies used for nuclear targeting. Its purpose is to prepare engineers and scientists to participate in wargames, exercises, and discussions with the Department of Defense. Terms such as Circular Error Probable, probability of hit and damage, damage expectancy, and the physical vulnerability system are discussed. Methods for compounding damage from multiple weapons applied to one target are presented.

  4. Defense Science Board Task Force on Defense Strategies for Advanced Ballistic and Cruise Missile Threats

    Science.gov (United States)

    2017-01-01

    annual investment of about $2.5 billion. The study also recommended that the Department of Defense enhance its ab ility to perform the kinds of broad...homeland fundamentally change the nature of the problem to one of strategic deterrence and that the spirit of the terms of reference was more...adversary investments in regional, precision attack cruise and ballistic threaten that foundation, investments that have dramatically increased both

  5. Macrophage migration inhibitory factor deficiency is associated with impaired killing of gram-negative bacteria by macrophages and increased susceptibility to Klebsiella pneumoniae sepsis.

    Science.gov (United States)

    Roger, Thierry; Delaloye, Julie; Chanson, Anne-Laure; Giddey, Marlyse; Le Roy, Didier; Calandra, Thierry

    2013-01-15

    The cytokine macrophage migration inhibitory factor (MIF) is an important component of the early proinflammatory response of the innate immune system. However, the antimicrobial defense mechanisms mediated by MIF remain fairly mysterious. In the present study, we examined whether MIF controls bacterial uptake and clearance by professional phagocytes, using wild-type and MIF-deficient macrophages. MIF deficiency did not affect bacterial phagocytosis, but it strongly impaired the killing of gram-negative bacteria by macrophages and host defenses against gram-negative bacterial infection, as shown by increased mortality in a Klebsiella pneumonia model. Consistent with MIF's regulatory role of Toll-like 4 expression in macrophages, MIF-deficient cells stimulated with lipopolysaccharide or Escherichia coli exhibited reduced nuclear factor κB activity and tumor necrosis factor (TNF) production. Addition of recombinant MIF or TNF corrected the killing defect of MIF-deficient macrophages. Together, these data show that MIF is a key mediator of host responses against gram-negative bacteria, acting in part via a modulation of bacterial killing by macrophages.

  6. Missile Defense Certification: Examination of the U.S. Navy Aegis Warship and U.S. Army Patriot Crew Certification Process

    Science.gov (United States)

    2008-09-01

    C. Ensure FP Status indicators posted IAW SSTO : ___ (1) WCS ___ (2) DEFCON ___ (3) MOC ___ (4) Alert State ___ (5) ADW... SSTO . ___ 6. Denial and destruction plans. ___ 7. Missile hazard/misfire procedures. ___ 8. General Knowledge of TABS, Switch/Indicator

  7. Killing machines: three pore-forming proteins of the immune system

    Science.gov (United States)

    McCormack, Ryan; de Armas, Lesley; Shiratsuchi, Motoaki

    2014-01-01

    The evolution of early multicellular eukaryotes 400–500 million years ago required a defensive strategy against microbial invasion. Pore-forming proteins containing the membrane-attack-complex-perforin (MACPF) domain were selected as the most efficient means to destroy bacteria or virally infected cells. The mechanism of pore formation by the MACPF domain is distinctive in that pore formation is purely physical and unspecific. The MACPF domain polymerizes, refolds, and inserts itself into bilayer membranes or bacterial outer cell walls. The displacement of surface lipid/carbohydrate molecules by the polymerizing MACPF domain creates clusters of large, water-filled holes that destabilize the barrier function and provide access for additional anti-bacterial or anti-viral effectors to sensitive sites that complete the destruction of the invader via enzymatic or chemical attack. The highly efficient mechanism of anti-microbial defense by a combined physical and chemical strategy using pore-forming MACPF-proteins has been retargeted during evolution of vertebrates and mammals for three purposes: (1) to kill extracellular bacteria C9/polyC9 evolved in conjunction with complement, (2) to kill virus infected and cancer cells perforin-1/polyperforin-1 CTL evolved targeted by NK and CTL, and (3) to kill intracellular bacteria transmembrane perforin-2/putative polyperforin-2 evolved targeted by phagocytic and nonphagocytic cells. Our laboratory has been involved in the discovery and description of each of the three pore-formers that will be reviewed here. PMID:24293008

  8. A fast online hit verification method for the single ion hit system at GSI

    International Nuclear Information System (INIS)

    Du, G.; Fischer, B.; Barberet, P.; Heiss, M.

    2006-01-01

    For a single ion hit facility built to irradiate specific targets inside biological cells, it is necessary to prove that the ions hit the selected targets reliably because the ion hits usually cannot be seen. That ability is traditionally tested either indirectly by aiming at pre-etched tracks in a nuclear track detector or directly by making the ion tracks inside cells visible using a stain coupled to special proteins produced in response to ion hits. However, both methods are time consuming and hits can be verified only after the experiment. This means that targeting errors in the experiment cannot be corrected during the experiment. Therefore, we have developed a fast online hit verification method that measures the targeting accuracy electronically with a spatial resolution of ±1 μm before cell irradiation takes place. (authors)

  9. Expanded Kill Chain Analysis of Manned-Unmanned Teaming for Future Strike Operations

    Science.gov (United States)

    2014-09-01

    the BLUEFORCE targeting and engagement kill chain to deter- mine areas of improvement or capability development to the chain. Opportunities exist to...systems integrated roadmap, FY2013 - 2038,” Department of Defense, Washington, DC, Tech. Rep. 14-S-0553, 2013. [7] B. Opall -Rome. (2014, Aug. 12). Israeli

  10. Comparison of gimbal approaches to decrease drag force and radar cross sectional area in missile application

    Science.gov (United States)

    Sakarya, Doǧan Uǧur

    2017-05-01

    Drag force effect is an important aspect of range performance in missile applications especially for long flight time. However, old fashioned gimbal approaches force to increase missile diameter. This increase has negative aspect of rising in both drag force and radar cross sectional area. A new gimbal approach was proposed recently. It uses a beam steering optical arrangement. Therefore, it needs less volume envelope for same field of regard and same optomechanical assembly than the old fashioned gimbal approaches. In addition to longer range performance achieved with same fuel in the new gimbal approach, this method provides smaller cross sectional area which can be more invisible in enemies' radar. In this paper, the two gimbal approaches - the old fashioned one and the new one- are compared in order to decrease drag force and radar cross sectional area in missile application. In this study; missile parameters are assumed to generate gimbal and optical design parameters. Optical design is performed according to these missile criteria. Two gimbal configurations are designed with respect to modeled missile parameters. Also analyzes are performed to show decreased drag force and radar cross sectional area in the new approach for comparison.

  11. Analysis of the overall structural behavior due to the impact of deformable missiles

    International Nuclear Information System (INIS)

    Ettouney, M.M.; Radini, R.R.; Hsueh, P.S.

    1979-01-01

    This paper presents a method of analysis to evaluate the overall behavior of reinforced concrete structures subjected to impact from deformable missiles. This method approaches the analysis in a very simple and practical way. The analysis is based on approximating the structure-missile system by a two-degree of freedom model. The two degrees of freedom model represents the missile and the structure, respectively. The hysteretic damping effects are considered implicitly through the nonlinearity of the two springs. Empirical formulas are presented for the evaluation of the dynamic properties of the nonlinear spring representing the concrete structure. The impact is simulated by applying an impulse on the two degrees of freedom system, then by the method of step by step numerical time integration (central difference formula is used) the time histories of the displacements and velocities of both the missile and structure are obtained. The numerical procedure is simple enough to be programmed by a hand or desk calculator which makes the method handy for most engineers and analysis. (orig.)

  12. A Terminal Guidance Law Based on Motion Camouflage Strategy of Air-to-Ground Missiles

    Directory of Open Access Journals (Sweden)

    Chang-sheng Gao

    2016-01-01

    Full Text Available A guidance law for attacking ground target based on motion camouflage strategy is proposed in this paper. According to the relative position between missile and target, the dual second-order dynamics model is derived. The missile guidance condition is given by analyzing the characteristic of motion camouflage strategy. Then, the terminal guidance law is derived by using the relative motion of missile and target and the guidance condition. In the process of derivation, the three-dimensional guidance law could be designed in a two-dimensional plane and the difficulty of guidance law design is reduced. A two-dimensional guidance law for three-dimensional space is derived by bringing the estimation for target maneuver. Finally, simulation for the proposed guidance law is taken and compared with pure proportional navigation. The simulation results demonstrate that the proposed guidance law can be applied to air-to-ground missiles.

  13. Design and Manufacturing Process for a Ballistic Missile

    Directory of Open Access Journals (Sweden)

    Zaharia Sebastian Marian

    2016-12-01

    Full Text Available Designing a ballistic missile flight depends on the mission and the stress to which the missile is subject. Missile’s requests are determined by: the organization of components; flight regime type, engine configuration and aerodynamic performance of the rocket flight. In this paper has been developed a ballistic missile with a smooth fuselage type, 10 control surfaces, 8 directional surfaces for cornering execution, 2 for maneuvers of execution to change the angle of incidence and 4 stabilizers direction. Through the technology of gluing and clamping of the shell and the use of titanium components, mass of ballistic missile presented a significant decrease in weight and a structure with high strength.

  14. Reconnaissance radiological characterization for the White Point Nike Missile Site, San Pedro, California

    International Nuclear Information System (INIS)

    Espegren, M.L.; Jensen, M.K.; Pierce, G.A.; Smith, S.M.

    1993-01-01

    This report is the result of field work performed at the former White Point Nike Missile Site, San Pedro, California. The Hazardous Waste Remedial Actions Program tasked the Oak Ridge National Laboratory Pollutant Assessments Group in Grand Junction, Colo., with this project. The objective was to determine whether or not radioisotopes possibly associated with past Department of Defense (DOD) operations were present and within accepted background levels. The radiation survey was accomplished by performing three independent radiation surveys, both outdoors and indoors, and random soil sampling. Initially, the site was land surveyed to develop a grid block system. A background radiation investigation was performed out in the San Pedro area

  15. A static-cidal assay for Trypanosoma brucei to aid hit prioritisation for progression into drug discovery programmes.

    Directory of Open Access Journals (Sweden)

    Manu De Rycker

    Full Text Available Human African Trypanosomiasis is a vector-borne disease of sub-Saharan Africa that causes significant morbidity and mortality. Current therapies have many drawbacks, and there is an urgent need for new, better medicines. Ideally such new treatments should be fast-acting cidal agents that cure the disease in as few doses as possible. Screening assays used for hit-discovery campaigns often do not distinguish cytocidal from cytostatic compounds and further detailed follow-up experiments are required. Such studies usually do not have the throughput required to test the large numbers of hits produced in a primary high-throughput screen. Here, we present a 384-well assay that is compatible with high-throughput screening and provides an initial indication of the cidal nature of a compound. The assay produces growth curves at ten compound concentrations by assessing trypanosome counts at 4, 24 and 48 hours after compound addition. A reduction in trypanosome counts over time is used as a marker for cidal activity. The lowest concentration at which cell killing is seen is a quantitative measure for the cidal activity of the compound. We show that the assay can identify compounds that have trypanostatic activity rather than cidal activity, and importantly, that results from primary high-throughput assays can overestimate the potency of compounds significantly. This is due to biphasic growth inhibition, which remains hidden at low starting cell densities and is revealed in our static-cidal assay. The assay presented here provides an important tool to follow-up hits from high-throughput screening campaigns and avoid progression of compounds that have poor prospects due to lack of cidal activity or overestimated potency.

  16. Department of the Army Justification of Estimates for Fiscal Year 1983 Submitted to Congress February 1982. Part 2 (Missiles).

    Science.gov (United States)

    1982-02-01

    is req’uested to procure 376 missiles and 12 fire units (or the PATRIOT missile system. PATRIOT Is an improved system which will replace NIKE -HERCULES...tifl UPrOveflts will be retofittd by Utetil work orders to be apple olwd yAm eo em 2-4S yebrary � MISSILE MODIFVICATION propriation: Missile

  17. Histones as mediators of host defense, inflammation and thrombosis

    OpenAIRE

    Hoeksema, Marloes; van Eijk, Martin; Haagsman, Henk P; Hartshorn, Kevan L

    2016-01-01

    Histones are known for their ability to bind to and regulate expression of DNA. However, histones are also present in cytoplasm and extracellular fluids where they serve host defense functions and promote inflammatory responses. Histones are a major component of neutrophil extracellular traps that contribute to bacterial killing but also to inflammatory injury. Histones can act as antimicrobial peptides and directly kill bacteria, fungi, parasites and viruses, in vitro and in a variety of ani...

  18. High energy ion hit technique to local area using microbeam

    Energy Technology Data Exchange (ETDEWEB)

    Tanaka, Ryuichi; Kamiya, Tomihiro; Suda, Tamotsu; Sakai, Takuro; Hirao, Toshio; Kobayashi, Yasuhiko; Watanabe, Hiroshi [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment

    1997-03-01

    Single energetic ion hit technique has been developed as an application of ion microbeam technique, in order to study the effect of local damage or injury to materials and living organisms. The overall performance is basically defined by those of separate techniques: microbeam formation, microbeam positioning, single ion detection, detection signal processing, hit timing control, and hit verification. Recent progress on the developments of these techniques at JAERI-TIARA facility are reviewed. (author)

  19. Impact load time histories for viscoelastic missiles

    International Nuclear Information System (INIS)

    Stoykovich, M.

    1977-01-01

    Generation of the impact load time history at the contact point between a viscoelastic missile and its targets is presented. In the past, in the case of aircraft striking containment shell structure, the impact load history was determined on the basis of actual measurements by subjecting a rigid wall to aircraft crash. The effects of elastic deformation of the target upon the impact load time history is formulated in this paper. The missile is idealized by a linear mass-spring-dashpot combination using viscoelastic models. These models can readily be processed taking into account the elastic as well as inelastic deformations of the missiles. The target is assumed to be either linearly elastic or rigid. In the case of the linearly elastic target, the normal mode theory is used to express the time-dependent displacements of the target which is simulated by lumped masses, elastic properties and dashpots in discrete parts. In the case of Maxwell viscoelastic model, the time-dependent displacements of the missile and the target are given in terms of the unknown impact load time history. This leads to an integral equation which may be solved by Laplace transformation. The normal mode theory is provided. Examples are given for bricks with viscoelastic materials as missiles against a rigid target. (Auth.)

  20. MYC/BCL2/BCL6 triple hit lymphoma: a study of 40 patients with a comparison to MYC/BCL2 and MYC/BCL6 double hit lymphomas.

    Science.gov (United States)

    Huang, Wenting; Medeiros, L Jeffrey; Lin, Pei; Wang, Wei; Tang, Guilin; Khoury, Joseph; Konoplev, Sergej; Yin, C Cameron; Xu, Jie; Oki, Yasuhiro; Li, Shaoying

    2018-05-21

    High-grade B-cell lymphomas with MYC, BCL2, and BCL6 rearrangements (triple hit lymphoma) are uncommon. We studied the clinicopathologic features of 40 patients with triple hit lymphoma and compared them to 157 patients with MYC/BCL2 double hit lymphoma and 13 patients with MYC/BCL6 double hit lymphoma. The triple hit lymphoma group included 25 men and 15 women with a median age of 61 years (range, 34-85). Nine patients had a history of B-cell lymphoma. Histologically, 23 (58%) cases were diffuse large B-cell lymphoma and 17 cases had features of B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma. Most cases of triple hit lymphoma were positive for CD10 (100%), BCL2 (95%), BCL6 (82%), MYC (74%), and 71% with MYC and BCL2 coexpression. P53 was overexpressed in 29% of triple hit lymphoma cases. The clinicopathological features of triple hit lymphoma patients were similar to patients with MYC/BCL2 and MYC/BCL6 double hit lymphoma, except that triple hit lymphoma cases were more often CD10 positive compared with MYC/BCL6 double hit lymphoma (p hit lymphoma and double hit lymphoma and overall survival in triple hit lymphoma patients was 17.6 months, similar to the overall survival of patients with double hit lymphoma (p = 0.67). Patients with triple hit lymphoma showing P53 overexpression had significantly worse overall survival compared with those without P53 overexpression (p = 0.04). On the other hand, double expressor status and prior history of B-cell lymphoma did not correlate with overall survival. In conclusion, most patients with triple hit lymphoma have an aggressive clinical course and poor prognosis and these tumors have a germinal center B-cell immunophenotype, similar to patients with double hit lymphomas. P53 expression is a poor prognostic factor in patients with triple hit lymphoma.

  1. In Support of the Common Defense: A Homeland Defense and Security Journal. Volume 2

    Science.gov (United States)

    2013-06-01

    create a coast-to-coast, interoperable digital emergency communications network.36 Accordingly, Homeland Security Act 2002 and Homeland Security...or fixed monitor that depicts friendly forces on an easy-to-read digitized geospatial map. The number of assets being tracked directly determines...Common Defense diminished since Colombian security forces killed notorious Medellin cartel leader Pablo Escobar in 1993.74 There undeniably is an

  2. A new guidance law for a tactical surface-to-surface missile

    Directory of Open Access Journals (Sweden)

    Danilo V. Ćuk

    2012-01-01

    Full Text Available Modern tactical surface-to-surface missiles, equipped with strapdown inertial navigation systems, achieve very good accuracy compared with free-flight rockets. The probable range dispersion mainly depends on instruments errors and longitudinal disturbances such as rocket motor total-impulse deviation as well as differences between the estimated and actual values of the axial force and head wind. This paper gives an extension of the correlated velocity concept for surface-to-surface missiles without a thrust-terminating mechanism. The calculated parameters of the correlated velocity are stored into the memory of an onboard guidance computer. On the basis of the correlated velocity concept, the modified proportional navigation with the adjustment of the time-to-go of the missile to the target was proposed. It is shown that the new guidance law can compensate for the longitudinal disturbances of different levels successfully. The effectiveness of the proposed guidance method was confirmed by means of the calculated probable range and lateral dispersion for the anticipated disturbances in the guidance system.

  3. Local damage to reinforced concrete structures caused by impact of aircraft engine missiles. Pt. 1

    International Nuclear Information System (INIS)

    Sugano, T.; Tsubota, H.; Kasai, Y.; Koshika, N.; Ohnuma, H.; Von Riesemann, W.A.; Bickel, D.C.; Parks, M.B.

    1993-01-01

    Structural damage induced by an aircraft crashing into a reinforced concrete structure includes local damage caused by the deformable engines, and global damage caused by the entire aircraft. Local damage to the target may consist of spalling of concrete from its front face together with missile penetration into it, scabbing of concrete from its rear face, and perforation of missile through it. Until now, local damage to concrete structures has been mainly evaluated by rigid missile impact tests. Past research work regarding local damage caused by impact of deformable missiles has been limited. This paper presents the results of a series of impact tests of small-, intermediate-, and full-scale engine models into reinforced concrete panels. The purpose of the tests was to determine the local damage to a reinforced concrete structure caused by the impact of a deformable aircraft engine. (orig.)

  4. Antimicrobial combinations: Bliss independence and Loewe additivity derived from mechanistic multi-hit models

    Science.gov (United States)

    Yu, Guozhi; Hozé, Nathanaël; Rolff, Jens

    2016-01-01

    Antimicrobial peptides (AMPs) and antibiotics reduce the net growth rate of bacterial populations they target. It is relevant to understand if effects of multiple antimicrobials are synergistic or antagonistic, in particular for AMP responses, because naturally occurring responses involve multiple AMPs. There are several competing proposals describing how multiple types of antimicrobials add up when applied in combination, such as Loewe additivity or Bliss independence. These additivity terms are defined ad hoc from abstract principles explaining the supposed interaction between the antimicrobials. Here, we link these ad hoc combination terms to a mathematical model that represents the dynamics of antimicrobial molecules hitting targets on bacterial cells. In this multi-hit model, bacteria are killed when a certain number of targets are hit by antimicrobials. Using this bottom-up approach reveals that Bliss independence should be the model of choice if no interaction between antimicrobial molecules is expected. Loewe additivity, on the other hand, describes scenarios in which antimicrobials affect the same components of the cell, i.e. are not acting independently. While our approach idealizes the dynamics of antimicrobials, it provides a conceptual underpinning of the additivity terms. The choice of the additivity term is essential to determine synergy or antagonism of antimicrobials. This article is part of the themed issue ‘Evolutionary ecology of arthropod antimicrobial peptides’. PMID:27160596

  5. Antimicrobial combinations: Bliss independence and Loewe additivity derived from mechanistic multi-hit models.

    Science.gov (United States)

    Baeder, Desiree Y; Yu, Guozhi; Hozé, Nathanaël; Rolff, Jens; Regoes, Roland R

    2016-05-26

    Antimicrobial peptides (AMPs) and antibiotics reduce the net growth rate of bacterial populations they target. It is relevant to understand if effects of multiple antimicrobials are synergistic or antagonistic, in particular for AMP responses, because naturally occurring responses involve multiple AMPs. There are several competing proposals describing how multiple types of antimicrobials add up when applied in combination, such as Loewe additivity or Bliss independence. These additivity terms are defined ad hoc from abstract principles explaining the supposed interaction between the antimicrobials. Here, we link these ad hoc combination terms to a mathematical model that represents the dynamics of antimicrobial molecules hitting targets on bacterial cells. In this multi-hit model, bacteria are killed when a certain number of targets are hit by antimicrobials. Using this bottom-up approach reveals that Bliss independence should be the model of choice if no interaction between antimicrobial molecules is expected. Loewe additivity, on the other hand, describes scenarios in which antimicrobials affect the same components of the cell, i.e. are not acting independently. While our approach idealizes the dynamics of antimicrobials, it provides a conceptual underpinning of the additivity terms. The choice of the additivity term is essential to determine synergy or antagonism of antimicrobials.This article is part of the themed issue 'Evolutionary ecology of arthropod antimicrobial peptides'. © 2016 The Author(s).

  6. An Annotated Bibliography of MANPRINT-Related Assessments and Evaluations Conducted by the U.S. Army, 2nd Edition: 1953 to 2009. Volume 1- Index

    Science.gov (United States)

    2010-02-01

    or 4 EndNote. (2008). Endnote, Windows Version X1. Berkeley, CA.: ISI ResearchSoft, Inc . An...M91 M91, 115mm Multiple Rocket Launcher MA 1962 Nike Zeus Missile- Air Defense- Nike Zeus Nike Zeus Missile System MA 1962 Patton M60E1 Vehicle...Version 6 2009 MA Nike Zeus Missile- Air Defense- Nike Zeus Nike Zeus Missile System 1962 T&ER NLA Shotgun- Cartridge- 12 Gauge- NLA 12 Gauge Shotgun

  7. The gastropod shell has been co-opted to kill parasitic nematodes.

    Science.gov (United States)

    Rae, R

    2017-07-06

    Exoskeletons have evolved 18 times independently over 550 MYA and are essential for the success of the Gastropoda. The gastropod shell shows a vast array of different sizes, shapes and structures, and is made of conchiolin and calcium carbonate, which provides protection from predators and extreme environmental conditions. Here, I report that the gastropod shell has another function and has been co-opted as a defense system to encase and kill parasitic nematodes. Upon infection, cells on the inner layer of the shell adhere to the nematode cuticle, swarm over its body and fuse it to the inside of the shell. Shells of wild Cepaea nemoralis, C. hortensis and Cornu aspersum from around the U.K. are heavily infected with several nematode species including Caenorhabditis elegans. By examining conchology collections I show that nematodes are permanently fixed in shells for hundreds of years and that nematode encapsulation is a pleisomorphic trait, prevalent in both the achatinoid and non-achatinoid clades of the Stylommatophora (and slugs and shelled slugs), which diverged 90-130 MYA. Taken together, these results show that the shell also evolved to kill parasitic nematodes and this is the only example of an exoskeleton that has been co-opted as an immune system.

  8. China Sanctions for Missile Proliferation: A Bureaucratic Compromise

    National Research Council Canada - National Science Library

    St. Amand, Gerard A

    1994-01-01

    On 12 August 26, 1993, the State Department announced that the United States would impose sanctions against China for transferring missile technology to Pakistan in violation of the Missile Technology Control Regime (MTCR...

  9. Politics and Procurement: The Clast Between Local Interest and Strategic Imperative in U.S. Defense Acquisition

    Science.gov (United States)

    2014-06-01

    Dwight Eisenhower set aside $137 million for the Nike -Zeus missile system. And John Kennedy, on the advice of Secretary of Defense Robert McNamara...scientists and engineers. Entry into the DGA and promotion to project managers, who were given the title of “armaments engineer,” required a degree from one

  10. Multi-Mode Electric Actuator Dynamic Modelling for Missile Fin Control

    Directory of Open Access Journals (Sweden)

    Bhimashankar Gurav

    2017-06-01

    Full Text Available Linear first/second order fin direct current (DC actuator model approximations for missile applications are currently limited to angular position and angular velocity state variables. Furthermore, existing literature with detailed DC motor models is decoupled from the application of interest: tail controller missile lateral acceleration (LATAX performance. This paper aims to integrate a generic DC fin actuator model with dual-mode feedforward and feedback control for tail-controlled missiles in conjunction with the autopilot system design. Moreover, the characteristics of the actuator torque information in relation to the aerodynamic fin loading for given missile trim velocities are also provided. The novelty of this paper is the integration of the missile LATAX autopilot states and actuator states including the motor torque, position and angular velocity. The advantage of such an approach is the parametric analysis and suitability of the fin actuator in relation to the missile lateral acceleration dynamic behaviour.

  11. Dirty Hits

    OpenAIRE

    Clarke, Louise

    2010-01-01

    Issue 9 of the Saatchi Gallery Magazine: Art&Music is dedicated to Sex. The article Dirty Hits invited a cross-section of contemporary artists and musicians to answer: What makes a dirty hit? As one of the artists invited, I wrote an autobiographical piece to reveal how these fumbling, feral sexual experiences of my childhood landscape, along with irrational superstition and folk law inform my life and underpin my work. The article also included an artwork: Louise Clarke, Sip (2009)

  12. Assessment of missiles generated by pressure component failure and its application to recent gas-cooled nuclear plant design

    International Nuclear Information System (INIS)

    Tulacz, J.; Smith, R.E.

    1980-01-01

    Methods for establishing characteristics of missiles following pressure barrier rupture have been reviewed in order to enable evaluation of structural response to missile impact and to aid the design of barriers to protect essential plant on gas cooled nuclear plant against unacceptable damage from missile impact. Methods for determining structural response of concrete barriers to missile impact have been reviewed and some methods used for assessing the adequacy of steel barriers on gas-cooled nuclear plant have been described. The possibility of making an incredibility case for some of the worst missiles based on probability arguments is briefly discussed. It is shown that there may be scope for such arguments but there are difficulties in quantifying some of the probability factors. (U.K.)

  13. The Killing Thought in the Eugenic Era and Today: A Commentary on Hollander's Essay.

    Science.gov (United States)

    Wolfensberger, Wolf

    1989-01-01

    Two responses to Hollander (EC 220 057) and the author's counter-response note similarities between "mercy killing" of people with mental retardation and deliberate abortion of the unborn, misuse of the history of eugenics, and a defense of the author's historical scholarship. (DB)

  14. Statistical properties and pre-hit dynamics of price limit hits in the Chinese stock markets.

    Science.gov (United States)

    Wan, Yu-Lei; Xie, Wen-Jie; Gu, Gao-Feng; Jiang, Zhi-Qiang; Chen, Wei; Xiong, Xiong; Zhang, Wei; Zhou, Wei-Xing

    2015-01-01

    Price limit trading rules are adopted in some stock markets (especially emerging markets) trying to cool off traders' short-term trading mania on individual stocks and increase market efficiency. Under such a microstructure, stocks may hit their up-limits and down-limits from time to time. However, the behaviors of price limit hits are not well studied partially due to the fact that main stock markets such as the US markets and most European markets do not set price limits. Here, we perform detailed analyses of the high-frequency data of all A-share common stocks traded on the Shanghai Stock Exchange and the Shenzhen Stock Exchange from 2000 to 2011 to investigate the statistical properties of price limit hits and the dynamical evolution of several important financial variables before stock price hits its limits. We compare the properties of up-limit hits and down-limit hits. We also divide the whole period into three bullish periods and three bearish periods to unveil possible differences during bullish and bearish market states. To uncover the impacts of stock capitalization on price limit hits, we partition all stocks into six portfolios according to their capitalizations on different trading days. We find that the price limit trading rule has a cooling-off effect (object to the magnet effect), indicating that the rule takes effect in the Chinese stock markets. We find that price continuation is much more likely to occur than price reversal on the next trading day after a limit-hitting day, especially for down-limit hits, which has potential practical values for market practitioners.

  15. From A-4 to Explorer 1. [U.S. rocket and missile technology historical review

    Science.gov (United States)

    Debus, K. H.

    1973-01-01

    Historical review of the development of rocket and missile technology in the United States over the period from 1945 to 1958. Attention is given to the organization of activities, the launch facilities, and the scope of test rocket firings at the White Sands Proving Ground area during the initial phase of research with captured German V2 rockets. The development of the Redstone missiles is outlined by discussing aspects of military involvement, cooperation with industrial suppliers, details of ground support equipment, and results of initial test firings. Subsequent development of the Jupiter missiles is examined in a similar manner, and attention is given to activities involved in the launching of the Explorer 1 satellite.

  16. Quantum walks with infinite hitting times

    International Nuclear Information System (INIS)

    Krovi, Hari; Brun, Todd A.

    2006-01-01

    Hitting times are the average time it takes a walk to reach a given final vertex from a given starting vertex. The hitting time for a classical random walk on a connected graph will always be finite. We show that, by contrast, quantum walks can have infinite hitting times for some initial states. We seek criteria to determine if a given walk on a graph will have infinite hitting times, and find a sufficient condition, which for discrete time quantum walks is that the degeneracy of the evolution operator be greater than the degree of the graph. The set of initial states which give an infinite hitting time form a subspace. The phenomenon of infinite hitting times is in general a consequence of the symmetry of the graph and its automorphism group. Using the irreducible representations of the automorphism group, we derive conditions such that quantum walks defined on this graph must have infinite hitting times for some initial states. In the case of the discrete walk, if this condition is satisfied the walk will have infinite hitting times for any choice of a coin operator, and we give a class of graphs with infinite hitting times for any choice of coin. Hitting times are not very well defined for continuous time quantum walks, but we show that the idea of infinite hitting-time walks naturally extends to the continuous time case as well

  17. Statistical Properties and Pre-Hit Dynamics of Price Limit Hits in the Chinese Stock Markets

    Science.gov (United States)

    Wan, Yu-Lei; Xie, Wen-Jie; Gu, Gao-Feng; Jiang, Zhi-Qiang; Chen, Wei; Xiong, Xiong; Zhang, Wei; Zhou, Wei-Xing

    2015-01-01

    Price limit trading rules are adopted in some stock markets (especially emerging markets) trying to cool off traders’ short-term trading mania on individual stocks and increase market efficiency. Under such a microstructure, stocks may hit their up-limits and down-limits from time to time. However, the behaviors of price limit hits are not well studied partially due to the fact that main stock markets such as the US markets and most European markets do not set price limits. Here, we perform detailed analyses of the high-frequency data of all A-share common stocks traded on the Shanghai Stock Exchange and the Shenzhen Stock Exchange from 2000 to 2011 to investigate the statistical properties of price limit hits and the dynamical evolution of several important financial variables before stock price hits its limits. We compare the properties of up-limit hits and down-limit hits. We also divide the whole period into three bullish periods and three bearish periods to unveil possible differences during bullish and bearish market states. To uncover the impacts of stock capitalization on price limit hits, we partition all stocks into six portfolios according to their capitalizations on different trading days. We find that the price limit trading rule has a cooling-off effect (object to the magnet effect), indicating that the rule takes effect in the Chinese stock markets. We find that price continuation is much more likely to occur than price reversal on the next trading day after a limit-hitting day, especially for down-limit hits, which has potential practical values for market practitioners. PMID:25874716

  18. Modeling and Simulation of Control Actuation System with Fuzzy-PID Logic Controlled Brushless Motor Drives for Missiles Glider Applications.

    Science.gov (United States)

    Muniraj, Murali; Arulmozhiyal, Ramaswamy

    2015-01-01

    A control actuation system has been used extensively in automotive, aerospace, and defense applications. The major challenges in modeling control actuation system are rise time, maximum peak to peak overshoot, and response to nonlinear system with percentage error. This paper addresses the challenges in modeling and real time implementation of control actuation system for missiles glider applications. As an alternative fuzzy-PID controller is proposed in BLDC motor drive followed by linkage mechanism to actuate fins in missiles and gliders. The proposed system will realize better rise time and less overshoot while operating in extreme nonlinear dynamic system conditions. A mathematical model of BLDC motor is derived in state space form. The complete control actuation system is modeled in MATLAB/Simulink environment and verified by performing simulation studies. A real time prototype of the control actuation is developed with dSPACE-1104 hardware controller and a detailed analysis is carried out to confirm the viability of the proposed system.

  19. The proliferation of ballistic missiles: an aggravating factor of crises

    International Nuclear Information System (INIS)

    Rousset, Valery

    2015-01-01

    After a brief recall of the history of the development of ballistic missiles from World War II, the author discusses the various uses of these missiles, on the one hand by major powers, and on the other hand by other countries like Israel, Pakistan and India, and also Egypt and Iraq. He recalls the uses of these missiles during regional conflicts (Scuds by Iraq) and then discusses the issue of proliferation of ballistic missiles. He notices that most of these weapons are present in the arsenal of major powers under the form of intercontinental missiles, intermediate range weapons or theatre weapons. On the Third World side, proliferation concerns short- and medium-range missiles produced from technology transfers or national programmes. Mobile systems are now present in all conflicts (notably Libya, Syria) and are now based on more advanced technologies for propellers as well as for control and guidance systems. In the last part, the author discusses the perspectives associated with these missiles which are a strong offensive weapon, and are also modernised to carry nuclear warheads or multiple warheads. These evolutions could put the western superiority into question again

  20. Final Programmatic Environmental Impact Statement for Defense Threat Reduction Agency (DTRA) Activities on White Sands Missile Range, New Mexico. Volume 1

    National Research Council Canada - National Science Library

    2007-01-01

    ...) activities at White Sands Missile Range (WSMR), New Mexico. It addresses future DTRA testing activities and expands on the current testing parameters addressed in existing National Environmental Policy Act (NEPA) documents...

  1. Preserving the ABM treaty: a critique of the Reagan Strategic Defense Initiative

    International Nuclear Information System (INIS)

    Drell, S.D.; Farley, P.J.; Holloway, D.

    1984-01-01

    President Reagan's Strategic Defense Initiative (SDI) proposal for long-term research and development on a leak-proof defense capability conflicts with the past 15 years of Soviet-American strategic relations and arms control negotiations. It represents a unilateral change, and will elicit a Soviet response based on how the Soviets think their own security may be affected. Whether the SDI transcends or enhances defense, it raises basic issues involving the US-Soviet strategic relationship. Emphasizing the central bearing of the Anti-Ballistic Missile (ABM) Treaty of 1972 the author reviews these issues and questions about the technical and strategic grounds of the proposal. Three recommendations are to limit the SDI program to a search for scientific possibilities, to consult with the Soviets on the ABM Treaty, and to recognize that the ABM Treaty will enhance security more than the SDI. 58 references

  2. 32 CFR Appendix B to Part 286 - Addressing FOIA Requests

    Science.gov (United States)

    2010-07-01

    ... Ballistic Missile Defense Organization Defense Systems Management College National Defense University Armed... 32 National Defense 2 2010-07-01 2010-07-01 false Addressing FOIA Requests B Appendix B to Part 286 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED...

  3. 76 FR 46756 - Privacy Act of 1974; System of Records

    Science.gov (United States)

    2011-08-03

    ...; System of Records AGENCY: Missile Defense Agency, Department of Defense (DoD). ACTION: Notice to Delete a System of Records. SUMMARY: The Missile Defense Agency proposes to delete a system of records notice in.... Peter Shearston, Missile Defense Agency, MDA/DXCM, 730 Irwin Ave, Schriever AFB, CO 80912-2101, or by...

  4. 32 CFR 525.1 - General.

    Science.gov (United States)

    2010-07-01

    ... airspace above. (3) National Range Commander. The Commander, Ballistic Missile Defense Systems Command, is... Missile Defense Systems Command, ATTN: BDMSC-R, P.O. Box 1500, Huntsville, Alabama 35807. Electrical...) Kwajalein Missile Range. Kwajalein Missile Range is defined as all those defense sites in the Kwajalein...

  5. Developing Health Information Technology (HIT) Programs and HIT Curriculum: The Southern Polytechnic State University Experience

    Science.gov (United States)

    Zhang, Chi; Reichgelt, Han; Rutherfoord, Rebecca H.; Wang, Andy Ju An

    2014-01-01

    Health Information Technology (HIT) professionals are in increasing demand as healthcare providers need help in the adoption and meaningful use of Electronic Health Record (EHR) systems while the HIT industry needs workforce skilled in HIT and EHR development. To respond to this increasing demand, the School of Computing and Software Engineering…

  6. Conditional probability of the tornado missile impact given a tornado occurrence

    International Nuclear Information System (INIS)

    Goodman, J.; Koch, J.E.

    1982-01-01

    Using an approach based on statistical mechanics, an expression for the probability of the first missile strike is developed. The expression depends on two generic parameters (injection probability eta(F) and height distribution psi(Z,F)), which are developed in this study, and one plant specific parameter (number of potential missiles N/sub p/). The expression for the joint probability of simultaneous impact of muitiple targets is also developed. This espression is applicable to calculation of the probability of common cause failure due to tornado missiles. It is shown that the probability of the first missile strike can be determined using a uniform missile distribution model. It is also shown that the conditional probability of the second strike, given the first, is underestimated by the uniform model. The probability of the second strike is greatly increased if the missiles are in clusters large enough to cover both targets

  7. 77 FR 68740 - 36(b)(1) Arms Sales Notification

    Science.gov (United States)

    2012-11-16

    ... Section 47(6) of the Arms Export Control Act. (iv) Military Department: Missile Defense Agency (VAA) (v... Terminal High Altitude Area Defense System (THAAD) Ballistic Missile Defense System contains classified..., forward deployable terminal missile defense system that represents significant technological advances. The...

  8. Evaluating missile fuels

    Energy Technology Data Exchange (ETDEWEB)

    Osmont, Antoine; Goekalp, Iskender [Laboratoire de Combustion et Systemes Reactifs (LCSR), CNRS, 1C, Orleans (France); Catoire, Laurent [University of Orleans, BP6749, 45067 Orleans (France); Laboratoire de Combustion et Systemes Reactifs (LCSR), CNRS, 1C, Orleans (France)

    2006-10-15

    This paper presents simple and relatively efficient methods to estimate some physical and chemical properties of polycyclic alkanes. These properties are melting point, normal boiling point, standard enthalpy of vaporization at 298 K, standard enthalpy of formation at 298 K, standard enthalpy of combustion at 298 K, density (specific gravity) and flash point. These methods are validated, despite the scarcity of experimental data, with several tens of polycyclic alkanes. Then the methods are used to estimate properties of some polycyclic alkanes, which are currently in use as missile fuels: JP-10, RJ-4 and RJ-5. Estimates and experimental data are found in good agreement for these fuels. This methodology is then used to evaluate missile fuel candidates to be used pure or as additive to JP-10 or to blends such as RJ-6. Several compounds are probably of interest for this task and their advantages and drawbacks are discussed. (Abstract Copyright [2006], Wiley Periodicals, Inc.)

  9. Exposure assessment of JAVELIN missile combustion products

    Science.gov (United States)

    Lundy, Donald O.; Langford, Roland E.

    1994-02-01

    Characterization and analysis of combustion products resulting from firing the JAVELIN missile were performed. Of those combustion products analyzed, it was determined that airborne lead concentrations exceeded the OSHA PEL of 50 micrograms each time the missile was fired while in the enclosure. Since the OSHA PEL standard is based upon a continuous rather than a short-term exposures blood lead concentrations were sought to ascertain the relationship between a short duration airborne exposure and its physiological effect on the body. Blood lead levels were taken on 49 test subjects prior to various JAVELIN missile test firings. Of those 49, 21 were outfitted With personal sampling equipment to determine airborne concentrations at the Assistant Gunner and Gunner positions. Periodic blood sampling after a single exposure showed an average increase of 2.27 micrograms/dL for all test subjects. Recommendations were made to consider changes in the positioning of the enclosure inhabitants to minimize airborne lead concentrations, to limit the number of missiles fired (situation dependent), and replacement of the lead B-resorcyolate with a non-lead containing burn rate modifier for the launch motor.

  10. Full-scale Tornado-missile impact tests

    International Nuclear Information System (INIS)

    1976-04-01

    Initial tests with four types of hypothetical tornado-borne missiles impacting reinforced concrete panels have been completed. Panel thicknesses are typical of walls in nuclear power facilities. In the seven tests, the missiles were rocket propelled to velocities currently postulated as being attainable by debris in tornadoes. The objective of the 18-test program is to ascertain the vulnerability of test panels to penetration and backface scabbing. The four missile types being tested are: a 1500-pound 35-foot long utility pole, an 8-pound 1-inch Grade 60 reinforcing bar, a 78-pound 3-inch Schedule 40 pipe, and a 743-pound 12-inch Schedule 40 pipe. The test panels are 12, 18, and 24 inches thick with 15 by 15 foot free spans. They were constructed to current minimum ACI standards: 3000 psi design strength (actual strength about 3600 psi) and 0.2 percent reinforcing steel area each way, each face (actual area is about 0.27 percent with bars on 12-inch centers). The 12-inch pipe has been identified as the critical missile for design of nuclear facility walls under currently specified impact conditions. The utility poles splintered upon impact causing virtually no impact damage, and the 3-inch pipe and 1-inch rebar were comparatively ineffectual because of their light weight

  11. Pricing Strategy, Pricing Stability and Financial Condition in the Defense Aerospace Industry

    OpenAIRE

    Johnstone, Jeffrey Carl; Keavney, Patrick Daniel

    1987-01-01

    Approved for public release, distribution unlimited The purpose of this research is to determine if pricing strategy and pricing stability for products in the defense aerospace industry can be predicted based on a firm's financial condition. The sample for this research includes 17 contractors and 52 missile and aircraft programs. Two separate issues are addressed. The first issue concerns the relationship between financial condition and contractor pricing strategy. The second concerns the...

  12. Hyperheat: a thermal signature model for super- and hypersonic missiles

    Science.gov (United States)

    van Binsbergen, S. A.; van Zelderen, B.; Veraar, R. G.; Bouquet, F.; Halswijk, W. H. C.; Schleijpen, H. M. A.

    2017-10-01

    In performance prediction of IR sensor systems for missile detection, apart from the sensor specifications, target signatures are essential variables. Very often, for velocities up to Mach 2-2.5, a simple model based on the aerodynamic heating of a perfect gas was used to calculate the temperatures of missile targets. This typically results in an overestimate of the target temperature with correspondingly large infrared signatures and detection ranges. Especially for even higher velocities, this approach is no longer accurate. Alternatives like CFD calculations typically require more complex sets of inputs and significantly more computing power. The MATLAB code Hyperheat was developed to calculate the time-resolved skin temperature of axisymmetric high speed missiles during flight, taking into account the behaviour of non-perfect gas and proper heat transfer to the missile surface. Allowing for variations in parameters like missile shape, altitude, atmospheric profile, angle of attack, flight duration and super- and hypersonic velocities up to Mach 30 enables more accurate calculations of the actual target temperature. The model calculates a map of the skin temperature of the missile, which is updated over the flight time of the missile. The sets of skin temperature maps are calculated within minutes, even for >100 km trajectories, and can be easily converted in thermal infrared signatures for further processing. This paper discusses the approach taken in Hyperheat. Then, the thermal signature of a set of typical missile threats is calculated using both the simple aerodynamic heating model and the Hyperheat code. The respective infrared signatures are compared, as well as the difference in the corresponding calculated detection ranges.

  13. DDG-1000 Missile Integration: A Case Study

    Science.gov (United States)

    2014-03-01

    Systems. 14. SUBJECT TERMS Systems Engineering, Integration 15. NUMBER OF PAGES 137 16. PRICE CODE 17. SECURITY CLASSIFICATION OF REPORT...military tasks. These range from detection and engagement of sea- skimming anti-ship cruise missiles to discrimination of a ballistic missile warhead...is affordable, funding is available, market research was conducted, an 32 analysis of alternatives was completed, the JROC is in agreement

  14. Effects of panaxadiol saponins on contents of TNF-α and IL-6 in two-hit rat models with hemorrhage and lipopolysaech

    International Nuclear Information System (INIS)

    Yu Zhenxiang; Ding Yanhua; Li Lu; Zhao Xuejian

    2005-01-01

    Objective: To explore the changes of serum TNF-α and IL-6 contents in the two-hit rat models with hemorrhage and lipopolysaech (LPS) and the effects of panaxadiol saponins (PDS) on TNF-α and contents IL-6. Methods: Adult Wistar rats were randomly divided into 5 groups: sham operational group (S), hemorrhage group (H), two-hit group with hemorrhage and LPS groups (HL), Dexamethasone pretreatment group (HLD), PDS pretreatment group (HLP). The rat models were made by hemorrhagic shock as the first hit and with endotoxin as the second hit. Then the rats were killed after 6 h. The contents of serum TNF-α and IL-6 in rats were measured by radioimmunoassay. Results: The serum TNF-α and IL-6 contents in HL group were increased significantly compared with S group or H group (P<0.001). The TNF-α and IL-6 contents in HLP group and HLD group were significantly lower than those in HL group (P<0.01). Conclusion: LPS can increase significantly the contents of serum TNF-α and IL-6 in rats with hemorrhagic shock. PDS can inhibit the release of serum TNF-α and IL-6, and has the same effects with DEX to protect against the tissue injuries of two-hit rats with hemorrhage and LPS. (authors)

  15. Ballistic Missile Defense: Let's Look Again before We Leap into Star Wars.

    Science.gov (United States)

    Morrison, David C.

    1985-01-01

    Americans must look beyond the superficial allure of President Reagan's Strategic Defense Initiative; they must search out the facts. Five pernicious myths on which this ill-considered proposal is founded are discussed. (RM)

  16. Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa.

    Science.gov (United States)

    Kirienko, Natalia V; Ausubel, Frederick M; Ruvkun, Gary

    2015-02-10

    In the arms race of bacterial pathogenesis, bacteria produce an array of toxins and virulence factors that disrupt core host processes. Hosts mitigate the ensuing damage by responding with immune countermeasures. The iron-binding siderophore pyoverdin is a key virulence mediator of the human pathogen Pseudomonas aeruginosa, but its pathogenic mechanism has not been established. Here we demonstrate that pyoverdin enters Caenorhabditis elegans and that it is sufficient to mediate host killing. Moreover, we show that iron chelation disrupts mitochondrial homeostasis and triggers mitophagy both in C. elegans and mammalian cells. Finally, we show that mitophagy provides protection both against the extracellular pathogen P. aeruginosa and to treatment with a xenobiotic chelator, phenanthroline, in C. elegans. Although autophagic machinery has been shown to target intracellular bacteria for degradation (a process known as xenophagy), our report establishes a role for authentic mitochondrial autophagy in the innate immune defense against P. aeruginosa.

  17. Nuclear arms race gearing for speedup

    International Nuclear Information System (INIS)

    Heylin, M.

    1981-01-01

    To probe the rationale behind the big buildup in US strategic arms that is presaged by the current enhanced R and D effort - and to explore the broader, more long-term role of science and technology in the nuclear arms race - C and EN in recent months spoke with a host of experts both within and outside the defense establishment. It is a topic of incredible complexity, high controversy, and of the highest stakes imaginable - the survival of civilization. This buildup will include over the next decade, apart from the MX, a new, highly accurate, submarine-launched ballistic missile and a fleet of very large submarines to carry it; an air-launched cruise missile; a new long-range bomber; a new intermediate-range missile and a new ground-launched cruise missile, both capable of hitting targets in the Soviet Union from proposed bases in Western Europe; and a new sea-launched cruise missile that can be fired from conventional submarines or other naval vessels. To spokesmen for, and members of, the defense establishment the US buildup is prudent, even minimal. According to them, it is needed to keep the US at least on a par with the growth of Soviet strategic might which was very substantial in the 1970's and which will carry over into the 1980's with further major gains. It also is needed to keep the lid on Soviet expansionism; and it is the best way to prevent a nuclear war. To critics, the proposed buildup is the height of lunacy. According to them, the US strategic arsenal is more than adequate today. And it can continue to serve its only legitimate purpose - to deter nuclear war, no matter how much the Soviets may choose to build up their nuclear forces - with a much-more-modest modernization program

  18. 77 FR 23250 - HIT Standards Committee; Schedule for the Assessment of HIT Policy Committee Recommendations

    Science.gov (United States)

    2012-04-18

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee; Schedule for the Assessment of HIT Policy Committee Recommendations AGENCY: Office of the National Coordinator for Health Information... 2009 mandates that the HIT Standards Committee develop a schedule for the assessment of policy...

  19. 76 FR 25355 - HIT Standards Committee; Schedule for the Assessment of HIT Policy Committee Recommendations

    Science.gov (United States)

    2011-05-04

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee; Schedule for the Assessment of HIT Policy Committee Recommendations AGENCY: Office of the National Coordinator for Health Information... 2009 mandates that the HIT Standards Committee develop a schedule for the assessment of policy...

  20. 78 FR 29134 - HIT Standards Committee; Schedule for the Assessment of HIT Policy Committee Recommendations

    Science.gov (United States)

    2013-05-17

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee; Schedule for the Assessment of HIT Policy Committee Recommendations AGENCY: Office of the National Coordinator for Health Information... 2009 mandates that the HIT Standards Committee develop a schedule for the assessment of policy...

  1. 75 FR 64714 - Meeting of the Chief of Naval Operations Executive Panel

    Science.gov (United States)

    2010-10-20

    ... recommendations of the Subcommittee on Navy's Role in Ballistic Missile Defense. The meeting will consist of discussions of Navy's role in ballistic missile defense, development of the global missile defense network and... DEPARTMENT OF DEFENSE Department of the Navy Meeting of the Chief of Naval Operations Executive...

  2. NATO’s Deterrence and Defense Posture After the Chicago Summit

    Science.gov (United States)

    2012-11-01

    were NATO, how would 28 nations manage the message when the stakes are so very high indeed? . . . What can we do now to prevent us from finding...miscalculation” and vulnerability to “a bear, a snake, a scorpion ,” or some other threat. “If NATO cannot use the words used by the IAEA and the UN...most of NATO’s strategic missile defense capability via its European Phased Adaptive Approach, this British participant asked, “ What does the U.S

  3. The Absence of NOD1 Enhances Killing of Aspergillus fumigatus Through Modulation of Dectin-1 Expression

    Directory of Open Access Journals (Sweden)

    Mark S. Gresnigt

    2017-12-01

    Full Text Available One of the major life-threatening infections for which severely immunocompromised patients are at risk is invasive aspergillosis (IA. Despite the current treatment options, the increasing antifungal resistance and poor outcome highlight the need for novel therapeutic strategies to improve outcome of patients with IA. In the current study, we investigated whether and how the intracellular pattern recognition receptor NOD1 is involved in host defense against Aspergillus fumigatus. When exploring the role of NOD1 in an experimental mouse model, we found that Nod1−/− mice were protected against IA and demonstrated reduced fungal outgrowth in the lungs. We found that macrophages derived from bone marrow of Nod1−/− mice were more efficiently inducing reactive oxygen species and cytokines in response to Aspergillus. Most strikingly, these cells were highly potent in killing A. fumigatus compared with wild-type cells. In line, human macrophages in which NOD1 was silenced demonstrated augmented Aspergillus killing and NOD1 stimulation decreased fungal killing. The differentially altered killing capacity of NOD1 silencing versus NOD1 activation was associated with alterations in dectin-1 expression, with activation of NOD1 reducing dectin-1 expression. Furthermore, we were able to demonstrate that Nod1−/− mice have elevated dectin-1 expression in the lung and bone marrow, and silencing of NOD1 gene expression in human macrophages increases dectin-1 expression. The enhanced dectin-1 expression may be the mechanism of enhanced fungal killing of Nod1−/− cells and human cells in which NOD1 was silenced, since blockade of dectin-1 reversed the augmented killing in these cells. Collectively, our data demonstrate that NOD1 receptor plays an inhibitory role in the host defense against Aspergillus. This provides a rationale to develop novel immunotherapeutic strategies for treatment of aspergillosis that target the NOD1 receptor, to enhance the

  4. Multi-hit time-to-amplitude CAMAC module (MTAC)

    International Nuclear Information System (INIS)

    Kang, H.

    1980-10-01

    A Multi-Hit Time-to-Amplitude Module (MTAC) for the SLAC Mark III drift chamber system has been designed to measure drift time by converting time-proportional chamber signals into analog levels, and converting the analog data by slow readout via a semi-autonomous controller in a CAMAC crate. The single width CAMAC module has 16 wire channels, each with a 4-hit capacity. An externally generated common start initiates an internal precision ramp voltage which is then sampled using a novel shift register gating scheme and CMOS sampling switches. The detailed design and performance specifications are described

  5. Male killing Spiroplasma protects Drosophila melanogaster against two parasitoid wasps

    Science.gov (United States)

    Xie, J; Butler, S; Sanchez, G; Mateos, M

    2014-01-01

    Maternally transmitted associations between endosymbiotic bacteria and insects are diverse and widespread in nature. Owing to imperfect vertical transmission, many heritable microbes have evolved compensational mechanisms to enhance their persistence in host lineages, such as manipulating host reproduction and conferring fitness benefits to host. Symbiont-mediated defense against natural enemies of hosts is increasingly recognized as an important mechanism by which endosymbionts enhance host fitness. Members of the genus Spiroplasma associated with distantly related Drosophila hosts are known to engage in either reproductive parasitism (i.e., male killing) or defense against natural enemies (the parasitic wasp Leptopilina heterotoma and a nematode). A male-killing strain of Spiroplasma (strain Melanogaster Sex Ratio Organism (MSRO)) co-occurs with Wolbachia (strain wMel) in certain wild populations of the model organism Drosophila melanogaster. We examined the effects of Spiroplasma MSRO and Wolbachia wMel on Drosophila survival against parasitism by two common wasps, Leptopilina heterotoma and Leptopilina boulardi, that differ in their host ranges and host evasion strategies. The results indicate that Spiroplasma MSRO prevents successful development of both wasps, and confers a small, albeit significant, increase in larva-to-adult survival of flies subjected to wasp attacks. We modeled the conditions under which defense can contribute to Spiroplasma persistence. Wolbachia also confers a weak, but significant, survival advantage to flies attacked by L. heterotoma. The host protective effects exhibited by Spiroplasma and Wolbachia are additive and may provide the conditions for such cotransmitted symbionts to become mutualists. Occurrence of Spiroplasma-mediated protection against distinct parasitoids in divergent Drosophila hosts suggests a general protection mechanism. PMID:24281548

  6. Multiple-hit parameter estimation in monolithic detectors.

    Science.gov (United States)

    Hunter, William C J; Barrett, Harrison H; Lewellen, Tom K; Miyaoka, Robert S

    2013-02-01

    We examine a maximum-a-posteriori method for estimating the primary interaction position of gamma rays with multiple interaction sites (hits) in a monolithic detector. In assessing the performance of a multiple-hit estimator over that of a conventional one-hit estimator, we consider a few different detector and readout configurations of a 50-mm-wide square cerium-doped lutetium oxyorthosilicate block. For this study, we use simulated data from SCOUT, a Monte-Carlo tool for photon tracking and modeling scintillation- camera output. With this tool, we determine estimate bias and variance for a multiple-hit estimator and compare these with similar metrics for a one-hit maximum-likelihood estimator, which assumes full energy deposition in one hit. We also examine the effect of event filtering on these metrics; for this purpose, we use a likelihood threshold to reject signals that are not likely to have been produced under the assumed likelihood model. Depending on detector design, we observe a 1%-12% improvement of intrinsic resolution for a 1-or-2-hit estimator as compared with a 1-hit estimator. We also observe improved differentiation of photopeak events using a 1-or-2-hit estimator as compared with the 1-hit estimator; more than 6% of photopeak events that were rejected by likelihood filtering for the 1-hit estimator were accurately identified as photopeak events and positioned without loss of resolution by a 1-or-2-hit estimator; for PET, this equates to at least a 12% improvement in coincidence-detection efficiency with likelihood filtering applied.

  7. Justification of Estimates for Fiscal Year 1984 Submitted to Congress January 1983: Missile Procurement.

    Science.gov (United States)

    1983-01-01

    initial procurement of 224 missiles (RDT&E PE 64314F, 27163F) STINGER - STINOER is a man-portable, shoulder fired , anti-aircraft missile system for...864 and will consist of a prefabricated metal wall and roof panels, steel framing, concrete floor (reinforoed/unreinforced), blast walls, monorail ...HVAC, fire protection system and normal facilities required of a building of this nature/function. Building will be designed to include energy

  8. Analysis of the development of missile-borne IR imaging detecting technologies

    Science.gov (United States)

    Fan, Jinxiang; Wang, Feng

    2017-10-01

    Today's infrared imaging guiding missiles are facing many challenges. With the development of targets' stealth, new-style IR countermeasures and penetrating technologies as well as the complexity of the operational environments, infrared imaging guiding missiles must meet the higher requirements of efficient target detection, capability of anti-interference and anti-jamming and the operational adaptability in complex, dynamic operating environments. Missileborne infrared imaging detecting systems are constrained by practical considerations like cost, size, weight and power (SWaP), and lifecycle requirements. Future-generation infrared imaging guiding missiles need to be resilient to changing operating environments and capable of doing more with fewer resources. Advanced IR imaging detecting and information exploring technologies are the key technologies that affect the future direction of IR imaging guidance missiles. Infrared imaging detecting and information exploring technologies research will support the development of more robust and efficient missile-borne infrared imaging detecting systems. Novelty IR imaging technologies, such as Infrared adaptive spectral imaging, are the key to effectively detect, recognize and track target under the complicated operating and countermeasures environments. Innovative information exploring techniques for the information of target, background and countermeasures provided by the detection system is the base for missile to recognize target and counter interference, jamming and countermeasure. Modular hardware and software development is the enabler for implementing multi-purpose, multi-function solutions. Uncooled IRFPA detectors and High-operating temperature IRFPA detectors as well as commercial-off-the-shelf (COTS) technology will support the implementing of low-cost infrared imaging guiding missiles. In this paper, the current status and features of missile-borne IR imaging detecting technologies are summarized. The key

  9. Performance Analysis and Optimal Allocation of Layered Defense M/M/N Queueing Systems

    Directory of Open Access Journals (Sweden)

    Longyue Li

    2016-01-01

    Full Text Available One important mission of strategic defense is to develop an integrated layered Ballistic Missile Defense System (BMDS. Motivated by the queueing theory, we presented a work for the representation, modeling, performance simulation, and channels optimal allocation of the layered BMDS M/M/N queueing systems. Firstly, in order to simulate the process of defense and to study the Defense Effectiveness (DE, we modeled and simulated the M/M/N queueing system of layered BMDS. Specifically, we proposed the M/M/N/N and M/M/N/C queueing model for short defense depth and long defense depth, respectively; single target channel and multiple target channels were distinguished in each model. Secondly, we considered the problem of assigning limited target channels to incoming targets, we illustrated how to allocate channels for achieving the best DE, and we also proposed a novel and robust search algorithm for obtaining the minimum channel requirements across a set of neighborhoods. Simultaneously, we presented examples of optimal allocation problems under different constraints. Thirdly, several simulation examples verified the effectiveness of the proposed queueing models. This work may help to understand the rules of queueing process and to provide optimal configuration suggestions for defense decision-making.

  10. Space missiles start-up impact on environment and dermatosis distribution for population residing areas adjacent to the 'Baikanur' space spot and to that of worked out stages of missile carriers fall: development and immunoprophylaxis measures

    International Nuclear Information System (INIS)

    Kozlovskij, V.A.; Mukhamedzhanov, Eh.K.

    2005-01-01

    This paper presents review of literary data of missile start-ups impact on environment and human health, condition of dermatological diseases in the regions adjacent to 'Baikanur' missile-space complex. It is reported that in-depth study upon assessment of dermatosis distribution for adults and children, development mechanisms of a number dermatological diseases under effect of excess ultraviolet radiation condition and that of asymmetrical dimethylhydrazine (heptyl) in the regions of possible impact of missile carrier's start-ups on dermatosis development epidemic process will be carried out. The study results will be compared with assessment of general level of population life within the last 20 years and adequacy of medicine, including dermatological care for the population. (author)

  11. Modeling and conduct of turbine missile concrete impact experiments

    International Nuclear Information System (INIS)

    Woodfin, R.L.

    1981-01-01

    The overall objective of the subject experiments was to provide full scale data on the response of reinforced concrete containment walls to impact and penetration by postulated turbine-produced missiles. These data can be used to validate analytical or scale modeling methods and to assess the applicability of current design formulas to penetration by large, irregularly shaped missiles. These data and results will be used in providing more realistic estimates of turbine missile damage probability in nuclear power plants with a non-peninsula arrangement. This paper describes the derivation of the test matrix and the method of conducting the experiments. (orig./HP)

  12. A new temperature threshold detector - Application to missile monitoring

    Science.gov (United States)

    Coston, C. J.; Higgins, E. V.

    Comprehensive thermal surveys within the case of solid propellant ballistic missile flight motors are highly desirable. For example, a problem involving motor failures due to insulator cracking at motor ignition, which took several years to solve, could have been identified immediately on the basis of a suitable thermal survey. Using conventional point measurements, such as those utilizing typical thermocouples, for such a survey on a full scale motor is not feasible because of the great number of sensors and measurements required. An alternate approach recognizes that temperatures below a threshold (which depends on the material being monitored) are acceptable, but higher temperatures exceed design margins. In this case hot spots can be located by a grid of wire-like sensors which are sensitive to temperature above the threshold anywhere along the sensor. A new type of temperature threshold detector is being developed for flight missile use. The considered device consists of KNO3 separating copper and Constantan metals. Above the KNO3 MP, galvanic action provides a voltage output of a few tenths of a volt.

  13. The SVT Hit Buffer

    International Nuclear Information System (INIS)

    Belforte, S.; Dell'Orso, M.; Donati, S.

    1996-01-01

    The Hit Buffer is part of the Silicon Vertex Tracker, a trigger processor dedicated to the reconstruction of particle trajectories in the Silicon Vertex Detector and the Central Tracking Chamber of the Collider Detector at Fermilab. The Hit Buffer is a high speed data-traffic node, where thousands of words are received in arbitrary order and simultaneously organized in an internal structured data base, to be later promptly retrieved and delivered in response to specific requests. The Hit Buffer is capable of processing data at a rate of 25 MHz, thanks to the use of special fast devices like Cache-Tag RAMs and high performance Erasable Programmable Logic Devices from the XILINX XC7300 family

  14. Database for High Throughput Screening Hits (dHITS): a simple tool to retrieve gene specific phenotypes from systematic screens done in yeast.

    Science.gov (United States)

    Chuartzman, Silvia G; Schuldiner, Maya

    2018-03-25

    In the last decade several collections of Saccharomyces cerevisiae yeast strains have been created. In these collections every gene is modified in a similar manner such as by a deletion or the addition of a protein tag. Such libraries have enabled a diversity of systematic screens, giving rise to large amounts of information regarding gene functions. However, often papers describing such screens focus on a single gene or a small set of genes and all other loci affecting the phenotype of choice ('hits') are only mentioned in tables that are provided as supplementary material and are often hard to retrieve or search. To help unify and make such data accessible, we have created a Database of High Throughput Screening Hits (dHITS). The dHITS database enables information to be obtained about screens in which genes of interest were found as well as the other genes that came up in that screen - all in a readily accessible and downloadable format. The ability to query large lists of genes at the same time provides a platform to easily analyse hits obtained from transcriptional analyses or other screens. We hope that this platform will serve as a tool to facilitate investigation of protein functions to the yeast community. © 2018 The Authors Yeast Published by John Wiley & Sons Ltd.

  15. Development process of muzzle flows including a gun-launched missile

    Directory of Open Access Journals (Sweden)

    Zhuo Changfei

    2015-04-01

    Full Text Available Numerical investigations on the launch process of a gun-launched missile from the muzzle of a cannon to the free-flight stage have been performed in this paper. The dynamic overlapped grids approach are applied to dealing with the problems of a moving gun-launched missile. The high-resolution upwind scheme (AUSMPW+ and the detailed reaction kinetics model are adopted to solve the chemical non-equilibrium Euler equations for dynamic grids. The development process and flow field structure of muzzle flows including a gun-launched missile are discussed in detail. This present numerical study confirms that complicated transient phenomena exist in the shortly launching stages when the gun-launched missile moves from the muzzle of a cannon to the free-flight stage. The propellant gas flows, the initial environmental ambient air flows and the moving missile mutually couple and interact. A complete structure of flow field is formed at the launching stages, including the blast wave, base shock, reflected shock, incident shock, shear layer, primary vortex ring and triple point.

  16. Cooperative Monitoring Center Occasional Paper/9: De-Alerting Strategic Ballistic Missiles

    Energy Technology Data Exchange (ETDEWEB)

    Connell, Leonard W.; Edenburn, Michael W.; Fraley, Stanley K.; Trost, Lawrence C.

    1999-03-01

    This paper presents a framework for evaluating the technical merits of strategic ballistic missile de-alerting measures, and it uses the framework to evaluate a variety of possible measures for silo-based, land-mobile, and submarine-based missiles. De-alerting measures are defined for the purpose of this paper as reversible actions taken to increase the time or effort required to launch a strategic ballistic missile. The paper does not assess the desirability of pursuing a de-alerting program. Such an assessment is highly context dependent. The paper postulates that if de-alerting is desirable and is used as an arms control mechanism, de-alerting measures should satisfy specific cirteria relating to force security, practicality, effectiveness, significant delay, and verifiability. Silo-launched missiles lend themselves most readily to de-alerting verification, because communications necessary for monitoring do not increase the vulnerabilty of the weapons by a significant amount. Land-mobile missile de-alerting measures would be more challenging to verify, because monitoring measures that disclose the launcher's location would potentially increase their vulnerability. Submarine-launched missile de-alerting measures would be extremely challlenging if not impossible to monitor without increasing the submarine's vulnerability.

  17. The New Chapter of the United States-Indonesia Defense Relations: Reengagement through IMET

    Science.gov (United States)

    2013-06-13

    influence except during President Sukarno’s administration. U.S. efforts in South Vietnam failed to prevent the North Vietnam communist government...terrorists launched a suicide bombing in Bali which killed over 200 locals and foreigners including Americans.67 This indicated that terrorists also...Indonesia suffered over 250,000 casualties because of this enormous natural disaster which hit Aceh and Nias, the north western tip of Indonesia’s

  18. 48 CFR 252.225-7018 - Notice of prohibition of certain contracts with foreign entities for the conduct of ballistic...

    Science.gov (United States)

    2010-10-01

    ... certain contracts with foreign entities for the conduct of ballistic missile defense research, development... foreign entities for the conduct of ballistic missile defense research, development, test, and evaluation... With Foreign Entities for the Conduct of Ballistic Missile Defense Research, Development, Test, and...

  19. Design of DOE facilities for wind-generated missiles

    International Nuclear Information System (INIS)

    Kuilanoff, G.; Drake, R.M.

    1991-01-01

    This paper presents criteria and procedures for the design of structures and components for wind-generated missiles. Methods for determining missile-induced loading, calculated structural response, performance requirements, and design considerations are covered. The presented criteria is applicable to Safety-Related concrete buildings as a whole and to all their exposed external components including walls, roofs, and supporting structural systems and elements

  20. The Apache Longbow-Hellfire Missile Test at Yuma Proving Ground: Ecological Risk Assessment for Missile Firing

    International Nuclear Information System (INIS)

    Jones, Daniel Steven; Efroymson, Rebecca Ann; Hargrove, William Walter; Suter, Glenn; Pater, Larry

    2008-01-01

    A multiple stressor risk assessment was conducted at Yuma Proving Ground, Arizona, as a demonstration of the Military Ecological Risk Assessment Framework. The focus was a testing program at Cibola Range, which involved an Apache Longbow helicopter firing Hellfire missiles at moving targets, M60-A1 tanks. This paper describes the ecological risk assessment for the missile launch and detonation. The primary stressor associated with this activity was sound. Other minor stressors included the detonation impact, shrapnel, and fire. Exposure to desert mule deer (Odocoileus hemionus crooki) was quantified using the Army sound contour program BNOISE2, as well as distances from the explosion to deer. Few effects data were available from related studies. Exposure-response models for the characterization of effects consisted of human 'disturbance' and hearing damage thresholds in units of C-weighted decibels (sound exposure level) and a distance-based No Observed Adverse Effects Level for moose and cannonfire. The risk characterization used a weight-of-evidence approach and concluded that risk to mule deer behavior from the missile firing was likely for a negligible number of deer, but that no risk to mule deer abundance and reproduction is expected

  1. Military Space Programs: Issues Concerning DOD's SBIRS and STSS Programs

    National Research Council Canada - National Science Library

    Smith, Marcia S

    2005-01-01

    .... The Space Tracking and Surveillance System (STSS, formerly SBIRS-Low), managed by the Missile Defense Agency, would perform missile tracking and target discrimination for missile defense objectives...

  2. Military Space Programs: Issues Concerning DOD's SBIRS and STSS Programs

    National Research Council Canada - National Science Library

    Smith, Marcia S

    2006-01-01

    .... The Space Tracking and Surveillance System (STSS, formerly SBIRS-Low), managed by the Missile Defense Agency, would perform missile tracking and target discrimination for missile defense objectives...

  3. Military Space Programs: Issues Concerning DOD's SBIRS and STSS Programs

    National Research Council Canada - National Science Library

    Smith, Marcia S

    2003-01-01

    .... The Space Tracking and Surveillance System (STSS, formerly SBIRS-Low), managed by the Missile Defense Agency, would perform missile tracking and target discrimination for missile defense objectives...

  4. Improvements to the ion Doppler spectrometer diagnostic on the HIT-SI experiments

    Science.gov (United States)

    Hossack, Aaron; Chandra, Rian; Everson, Chris; Jarboe, Tom

    2018-03-01

    An ion Doppler spectrometer diagnostic system measuring impurity ion temperature and velocity on the HIT-SI and HIT-SI3 spheromak devices has been improved with higher spatiotemporal resolution and lower error than previously described devices. Hardware and software improvements to the established technique have resulted in a record of 6.9 μs temporal and ≤2.8 cm spatial resolution in the midplane of each device. These allow Ciii and Oii flow, displacement, and temperature profiles to be observed simultaneously. With 72 fused-silica fiber channels in two independent bundles, and an f/8.5 Czerny-Turner spectrometer coupled to a video camera, frame rates of up to ten times the imposed magnetic perturbation frequency of 14.5 kHz were achieved in HIT-SI, viewing the upper half of the midplane. In HIT-SI3, frame rates of up to eight times the perturbation frequency were achieved viewing both halves of the midplane. Biorthogonal decomposition is used as a novel filtering tool, reducing uncertainty in ion temperature from ≲13 to ≲5 eV (with an instrument temperature of 8-16 eV) and uncertainty in velocity from ≲2 to ≲1 km/s. Doppler shift and broadening are calculated via the Levenberg-Marquardt algorithm, after which the errors in velocity and temperature are uniquely specified. Axisymmetric temperature profiles on HIT-SI3 for Ciii peaked near the inboard current separatrix at ≈40 eV are observed. Axisymmetric plasma displacement profiles have been measured on HIT-SI3, peaking at ≈6 cm at the outboard separatrix. Both profiles agree with the upper half of the midplane observable by HIT-SI. With its complete midplane view, HIT-SI3 has unambiguously extracted axisymmetric, toroidal current dependent rotation of up to 3 km/s. Analysis of the temporal phase of the displacement uncovers a coherent structure, locked to the applied perturbation. Previously described diagnostic systems could not achieve such results.

  5. Tracking, aiming, and hitting the UAV with ordinary assault rifle

    Science.gov (United States)

    Racek, František; Baláž, Teodor; Krejčí, Jaroslav; Procházka, Stanislav; Macko, Martin

    2017-10-01

    The usage small-unmanned aerial vehicles (UAVs) is significantly increasing nowadays. They are being used as a carrier of military spy and reconnaissance devices (taking photos, live video streaming and so on), or as a carrier of potentially dangerous cargo (intended for destruction and killing). Both ways of utilizing the UAV cause the necessity to disable it. From the military point of view, to disable the UAV means to bring it down by a weapon of an ordinary soldier that is the assault rifle. This task can be challenging for the soldier because he needs visually detect and identify the target, track the target visually and aim on the target. The final success of the soldier's mission depends not only on the said visual tasks, but also on the properties of the weapon and ammunition. The paper deals with possible methods of prediction of probability of hitting the UAV targets.

  6. Problems of Air Defense - and - Appedicies. Volumes I-III

    Science.gov (United States)

    1951-08-01

    interceptor. The FALCON program has elected to exploit the kill potential of11nl those lmisil-es that actually hit the target, writing off as...AP-PENDIX P-2 PROJECT CHARtLES -BH!EFINUt- SCHEDULE e4 -l rm nr ý4 SECRET APPEN-DIX P-)2 BRIEFING S- iELT ",UL• FOR PROJECT CHARLES (19 February -- 12...dais communicate with a -rack marker and indicate a specific track before a nurn2-er has beeu as3dgned to it. Another is the need for writing track

  7. Internal Shear Forging Processes for Missile Primary Structures.

    Science.gov (United States)

    1981-07-20

    Growth in Shear Forming," Trans. ASME, J. Eng. ind., Vol. 90, 1968, pp. 63-70. 1 28. H. J. Dreikandt, "Untersuchung Uber das DrUckwalzen zylindrisher...10 US Army Missile Command ATTN: DRSMI-RLM Redstone Arsenal, AL 35809 Comma nder 12 US Army Missile Command + camera-ready master ATTN: DRDMI- EAT

  8. Full-scale tornado-missile impact tests. Interim report

    International Nuclear Information System (INIS)

    Stephenson, A.E.

    1976-04-01

    Seven completed initial tests are described with 4 types of hypothetical tornado-borne missiles (impacting reinforced concrete panels that are typical of walls in nuclear power facilities). The missiles were rocket propelled to velocities currently postulated as being attainable by debris in tornadoes. (1500-pound 35-foot long utility pole; 8-pound 1-inch Grade 60 reinforcing bar; 78-pound 3-inch Schedule 40 pipe; and 743-pound 12-inch Schedule 40 pipe;) The results show that a minimum thickness of 24 inches is sufficient to prevent backface scabbing from normal impacts of currently postulated tornado missiles and that existing power plant walls are adequate for the most severe conditions currently postulated by regulatory agencies. This report gives selected detailed data on the tests completed thus far, including strain, panel velocity, and reaction histories

  9. 76 FR 80903 - Mandatory Declassification Review Addresses

    Science.gov (United States)

    2011-12-27

    ... John J. Kingman Road, Fort Belvoir, VA 22060-6201. (13) Missile Defense Agency. Missile Defense Agency... DEPARTMENT OF DEFENSE Office of the Secretary Mandatory Declassification Review Addresses AGENCY: Department of Defense. ACTION: Notice. SUMMARY: Pursuant to the Information Security Oversight Office's...

  10. Key considerations in infrared simulations of the missile-aircraft engagement

    CSIR Research Space (South Africa)

    Willers, MS

    2012-09-01

    Full Text Available is required to steer the missile towards the target, using the seeker-provided target sight-line for missile guidance.These requirements are satisfied by detailed models for aerodynamics, flight control servos, the auto-pilot and guidance and navigation...

  11. Joint Air-to-Surface Standoff Missile (JASSM)

    Science.gov (United States)

    2015-12-01

    6.1.3) All Ops All Ops Joint Critical Ops All Ops All Ops Missile Reliability (KSA) (CPD para 6.2.8) 4th Lot .91 4th Lot .91 IOT &E .80 4th Lot .85 IOT &E...the ORD 303-95-III dated January 20, 2004 Change Explanations None Acronyms and Abbreviations IOT &E - Initial Operational Test and Evaluation KSA... Actuator Control Card, Lots 12 and 4 Systems Engineering Program Support/Program Tooling and Test Equipment, and JASSM-ER Standard Data Protocol (DS

  12. Feasibility of missile guidance using MEMS-based active flow control

    International Nuclear Information System (INIS)

    DeChamplain, A.; Hamel, N.; Rainville, P.-A.; Gosselin, P.; Wong, F.

    2002-01-01

    The aim of this study was to evaluate the feasibility to control a missile or rocket by mean of an active flow control device such as MEMS (Micro Electro Mechanical Systems) in the form of a microbubble. For this simple aerodynamic form coupled to the geometry of a generic missile, different microbubble arrangements can have a very significant impact in steady operation. Using CFD, combinations of different microbubble configurations (ratio between the apparent diameter and apparent height) and positions on the surface of the missile were evaluated for their impact on overall system performance for a missile flying at Mach 2.5 at an altitude of 6 km at a zero angle of attack. From a validation study with the generic missile geometry tested experimentally, the Fluent commercial code gave an excellent accuracy of 2% for the drag coefficient. With the appropriate numerical parameters from the validation, different configurations of microbubble(s) were simulated to give only marginal changes to the coefficient of moment as compared to experimental values at an angle of attack of 14 degrees. Considering the major advantages in weight and space savings, this would certainly be a technology to implement for small changes in guidance parameters. (author)

  13. Extracellular traps are associated with human and mouse neutrophil and macrophage mediated killing of larval Strongyloides stercoralis.

    Science.gov (United States)

    Bonne-Année, Sandra; Kerepesi, Laura A; Hess, Jessica A; Wesolowski, Jordan; Paumet, Fabienne; Lok, James B; Nolan, Thomas J; Abraham, David

    2014-06-01

    Neutrophils are multifaceted cells that are often the immune system's first line of defense. Human and murine cells release extracellular DNA traps (ETs) in response to several pathogens and diseases. Neutrophil extracellular trap (NET) formation is crucial to trapping and killing extracellular pathogens. Aside from neutrophils, macrophages and eosinophils also release ETs. We hypothesized that ETs serve as a mechanism of ensnaring the large and highly motile helminth parasite Strongyloides stercoralis thereby providing a static target for the immune response. We demonstrated that S. stercoralis larvae trigger the release of ETs by human neutrophils and macrophages. Analysis of NETs revealed that NETs trapped but did not kill larvae. Induction of NETs was essential for larval killing by human but not murine neutrophils and macrophages in vitro. In mice, extracellular traps were induced following infection with S. stercoralis larvae and were present in the microenvironment of worms being killed in vivo. These findings demonstrate that NETs ensnare the parasite facilitating larval killing by cells of the immune system. Copyright © 2014 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

  14. Trade-offs between competition and defense specialists among unicellular planktonic organisms: the "killing the winner" hypothesis revisited.

    Science.gov (United States)

    Winter, Christian; Bouvier, Thierry; Weinbauer, Markus G; Thingstad, T Frede

    2010-03-01

    A trade-off between strategies maximizing growth and minimizing losses appears to be a fundamental property of evolving biological entities existing in environments with limited resources. In the special case of unicellular planktonic organisms, the theoretical framework describing the trade-offs between competition and defense specialists is known as the "killing the winner" hypothesis (KtW). KtW describes how the availability of resources and the actions of predators (e.g., heterotrophic flagellates) and parasites (e.g., viruses) determine the composition and biogeochemical impact of such organisms. We extend KtW conceptually by introducing size- or shape-selective grazing of protozoans on prokaryotes into an idealized food web composed of prokaryotes, lytic viruses infecting prokaryotes, and protozoans. This results in a hierarchy analogous to a Russian doll, where KtW principles are at work on a lower level due to selective viral infection and on an upper level due to size- or shape-selective grazing by protozoans. Additionally, we critically discuss predictions and limitations of KtW in light of the recent literature, with particular focus on typically neglected aspects of KtW. Many aspects of KtW have been corroborated by in situ and experimental studies of isolates and natural communities. However, a thorough test of KtW is still hampered by current methodological limitations. In particular, the quantification of nutrient uptake rates of the competing prokaryotic populations and virus population-specific adsorption and decay rates appears to be the most daunting challenge for the years to come.

  15. How I treat double-hit lymphoma.

    Science.gov (United States)

    Friedberg, Jonathan W

    2017-08-03

    The 2016 revision of the World Health Organization (WHO) classification for lymphoma has included a new category of lymphoma, separate from diffuse large B-cell lymphoma, termed high-grade B-cell lymphoma with translocations involving myc and bcl-2 or bcl-6 . These lymphomas, which occur in hit lymphomas (or triple-hit lymphomas if all 3 rearrangements are present). It is important to differentiate these lymphomas from the larger group of double-expressor lymphomas, which have increased expression of MYC and BCL-2 and/or BCL-6 by immunohistochemistry, by using variable cutoff percentages to define positivity. Patients with double-hit lymphomas have a poor prognosis when treated with standard chemoimmunotherapy and have increased risk of central nervous system involvement and progression. Double-hit lymphomas may arise as a consequence of the transformation of the underlying indolent lymphoma. There are no published prospective trials in double-hit lymphoma, however retrospective studies strongly suggest that aggressive induction regimens may confer a superior outcome. In this article, I review my approach to the evaluation and treatment of double-hit lymphoma, with an eye toward future clinical trials incorporating rational targeted agents into the therapeutic armamentarium. © 2017 by The American Society of Hematology.

  16. Numerical simulation of tornado-borne missile impact on reinforced concrete targets

    International Nuclear Information System (INIS)

    Tu, D.K.; Larder, R.

    1979-02-01

    This study is a continuation of the Lawrence Livermore Laboratory (LLL) effort to evaluate the applicability of using the finite element procedure to numerically simulate the impact of tornado-borne missiles on reinforced concrete targets. The objective of this study is to assess the back-face scab threshold of a reinforced concrete target impacted by deformable and nondeformable missiles. Several simulations were run using slug and pipe-type impacting missiles. The numerical results were compared with full-scale experimental field tests

  17. Iceberg killing fields limit huge potential for benthic blue carbon in Antarctic shallows.

    Science.gov (United States)

    Barnes, David K A

    2017-07-01

    Climate-forced ice losses are increasing potential for iceberg-seabed collisions, termed ice scour. At Ryder Bay, West Antarctic Peninsula (WAP) sea ice, oceanography, phytoplankton and encrusting zoobenthos have been monitored since 1998. In 2003, grids of seabed markers, covering 225 m 2 , were established, surveyed and replaced annually to measure ice scour frequency. Disturbance history has been recorded for each m 2 of seabed monitored at 5-25 m for ~13 years. Encrusting fauna, collected from impacted and nonimpacted metres each year, show coincident benthos responses in growth, mortality and mass of benthic immobilized carbon. Encrusting benthic growth was mainly determined by microalgal bloom duration; each day, nanophytoplankton exceeded 200 μg L -1 produced ~0.05 mm radial growth of bryozoans, and sea temperature >0 °C added 0.002 mm day -1 . Mortality and persistence of growth, as benthic carbon immobilization, were mainly influenced by ice scour. Nearly 30% of monitored seabed was hit each year, and just 7% of shallows were not hit. Hits in deeper water were more deadly, but less frequent, so mortality decreased with depth. Five-year recovery time doubled benthic carbon stocks. Scour-driven mortality varied annually, with two-thirds of all monitored fauna killed in a single year (2009). Reduced fast ice after 2006 ramped iceberg scouring, killing half the encrusting benthos each year in following years. Ice scour coupled with low phytoplankton biomass drove a phase shift to high mortality and depressed zoobenthic immobilized carbon stocks, which has persevered for 10 years since. Stocks of immobilized benthic carbon averaged nearly 15 g m -2 . WAP ice scouring may be recycling 80 000 tonnes of carbon yr -1 . Without scouring, such carbon would remain immobilized and the 2.3% of shelf which are shallows could be as productive as all the remaining continental shelf. The region's future, when glaciers reach grounding lines and iceberg

  18. Missile defence : An overview

    NARCIS (Netherlands)

    Weimar, P.W.L.

    2012-01-01

    At the present day, an unparalleled number of international actors, be it national governments or non-state groups, have acquired or are seeking to acquire both weapons of mass destruction and the means to deliver them. Those means of delivery can be Ballistic Missiles that can bridge vast – even

  19. Full-scale impact test data for tornado-missile design of nuclear plants

    International Nuclear Information System (INIS)

    Stephenson, A.E.; Sliter, G.E.

    1977-01-01

    It is standard practice to consider the effects of low-probability impacts of tornado-borne debris (''tornado missiles'' such as utility poles and steel pipes) in the structural design of nuclear power plants in the United States. To provide data that can be used directly in the design procedure, a series of full-scale tornado-missile impact tests was performed. This paper is a brief summary of the results and conclusions from these tests. The tests consisted of reinforced concrete panels impacted by poles, pipes, and rods propelled by a rocket sled. The panels were constructed to current minimum standards and had thicknesses typical of auxiliary buildings of nuclear power plants. A specific objective was the determination of the impact velocities below which the panels do not experience backface scabbing. Another objective was to assess the adequacy of (1) conventional design formulae for penetration and scabbing and (2) conventional design methods for overall structural response. Test missiles and velocities represented those in current design standards. Missiles included utility poles, steel pipes, and steel bars. It is important to interpret the data in this paper in recognition that the test conditions represent conservative assumptions regarding maximum wind speeds, injection of the missile into the wind stream, aerodynamic trajectory, and orientation of missile at impact. Even with the severe assumptions made, the full-scale tests described demonstrate the ability of prototypical nuclear plant walls and roofs to provide adequate protection against postulated tornado-missile impact

  20. Staphylococcus epidermidis strategies to avoid killing by human neutrophils.

    Directory of Open Access Journals (Sweden)

    Gordon Y C Cheung

    2010-10-01

    Full Text Available Staphylococcus epidermidis is a leading nosocomial pathogen. In contrast to its more aggressive relative S. aureus, it causes chronic rather than acute infections. In highly virulent S. aureus, phenol-soluble modulins (PSMs contribute significantly to immune evasion and aggressive virulence by their strong ability to lyse human neutrophils. Members of the PSM family are also produced by S. epidermidis, but their role in immune evasion is not known. Notably, strong cytolytic capacity of S. epidermidis PSMs would be at odds with the notion that S. epidermidis is a less aggressive pathogen than S. aureus, prompting us to examine the biological activities of S. epidermidis PSMs. Surprisingly, we found that S. epidermidis has the capacity to produce PSMδ, a potent leukocyte toxin, representing the first potent cytolysin to be identified in that pathogen. However, production of strongly cytolytic PSMs was low in S. epidermidis, explaining its low cytolytic potency. Interestingly, the different approaches of S. epidermidis and S. aureus to causing human disease are thus reflected by the adaptation of biological activities within one family of virulence determinants, the PSMs. Nevertheless, S. epidermidis has the capacity to evade neutrophil killing, a phenomenon we found is partly mediated by resistance mechanisms to antimicrobial peptides (AMPs, including the protease SepA, which degrades AMPs, and the AMP sensor/resistance regulator, Aps (GraRS. These findings establish a significant function of SepA and Aps in S. epidermidis immune evasion and explain in part why S. epidermidis may evade elimination by innate host defense despite the lack of cytolytic toxin expression. Our study shows that the strategy of S. epidermidis to evade elimination by human neutrophils is characterized by a passive defense approach and provides molecular evidence to support the notion that S. epidermidis is a less aggressive pathogen than S. aureus.

  1. Offensive Counterterrorism Targeted killing in eliminating terrorist target: the case of the USA and Israel

    Directory of Open Access Journals (Sweden)

    Hermínio Matos

    2012-01-01

    Full Text Available Due to the "global terrorism project", some States have adopted offensive counterterrorism measures which, though within national strategies on security and defense, contemplate the use of military power and the use of lethal force against non-state actors - individuals, groups or terrorist organizations - beyond their national borders. Reformulating the security paradigm has led, in these cases, to policies against terrorism. This is the case of targeted killing - the killing of selected targets - by the USA and Israel. Targeted killing actions - using essentially but not only drones - in Pakistan and Yemen by the American administration, a well as the Israeli response to Palestinian terrorism, are under heated debate in terms of their efficiency and legality. Thus, this paper aims to not only provide an analytical framework on this theme but also analyze the scope and impact of these counter terrorist strategies by the two countries.

  2. Sources Of Evolution Of The Japan Air Self Defense Force’s Strategy

    Science.gov (United States)

    2016-12-01

    national security. • Second is the battle space of war. “Defensive defense” strategy conducts war definitely in its territory and bears that most of its...russia-in- 2016/. 271Ankit Panda , “East China Sea: Japan Reacts as Chinese Air Force Conducts Miyako Strait Drill,” Diplomat, September 26, 2016...June 22, 2016. http://www.voanews.com/a/north-korea- failed-missile-tests-show-real-progress/3386692.html. Panda , Ankit. “East China Sea: Japan Reacts

  3. Reliability Evaluation for the Surface to Air Missile Weapon Based on Cloud Model

    Directory of Open Access Journals (Sweden)

    Deng Jianjun

    2015-01-01

    Full Text Available The fuzziness and randomness is integrated by using digital characteristics, such as Expected value, Entropy and Hyper entropy. The cloud model adapted to reliability evaluation is put forward based on the concept of the surface to air missile weapon. The cloud scale of the qualitative evaluation is constructed, and the quantitative variable and the qualitative variable in the system reliability evaluation are corresponded. The practical calculation result shows that it is more effective to analyze the reliability of the surface to air missile weapon by this way. The practical calculation result also reflects the model expressed by cloud theory is more consistent with the human thinking style of uncertainty.

  4. Application of a Complex Lead Compensator for a Laser Guided Missile

    Science.gov (United States)

    Akhila, M. R.; Gopika, S.; Abraham, R. J.

    2013-01-01

    This paper discusses the application of a lead compensator with complex pole and complex zero for a missile. It is compared with a lead compensator with real pole and real zero. A typical laser guided missile control system is considered for the performance comparison of both the compensators. Simulation studies carried out with MATLAB brings out the scope of using complex compensator in missile guided systems.

  5. 77 FR 68742 - 36(b)(1) Arms Sales Notification

    Science.gov (United States)

    2012-11-16

    ... missile defense capability, strengthen its homeland defense, and deter regional threats. The proposed sale... Defense System continues to hold a significant technology lead over other surface-to-air missile systems... DEPARTMENT OF DEFENSE Office of the Secretary [Transmittal Nos. 12-58] 36(b)(1) Arms Sales...

  6. Real Knockouts The Physical Feminism of Women's Self-Defense

    CERN Document Server

    McCaughey, Martha

    1997-01-01

    An examination of women's self-defense culture and its relationship to feminism. I was once a frightened feminist. So begins Martha McCaughey's odyssey into the dynamic world of women's self- defense, a culture which transforms women involved with it and which has equally profound implications for feminist theory and activism. Unprecedented numbers of American women are learning how to knock out, maim, even kill men who assault them. Sales of mace and pepper spray have skyrocketed. Some 14 million women own handguns. From behind the scenes at gun ranges, martial arts dojos, fitness centers off

  7. Recent Improvements in the SHIELD-HIT Code

    DEFF Research Database (Denmark)

    Hansen, David Christoffer; Lühr, Armin Christian; Herrmann, Rochus

    2012-01-01

    Purpose: The SHIELD-HIT Monte Carlo particle transport code has previously been used to study a wide range of problems for heavy-ion treatment and has been benchmarked extensively against other Monte Carlo codes and experimental data. Here, an improved version of SHIELD-HIT is developed concentra......Purpose: The SHIELD-HIT Monte Carlo particle transport code has previously been used to study a wide range of problems for heavy-ion treatment and has been benchmarked extensively against other Monte Carlo codes and experimental data. Here, an improved version of SHIELD-HIT is developed...

  8. Current insights into the laboratory diagnosis of HIT.

    Science.gov (United States)

    Bakchoul, T; Zöllner, H; Greinacher, A

    2014-06-01

    Heparin-induced thrombocytopenia (HIT) is an adverse drug reaction and prothrombotic disorder caused by immunization against platelet factor 4 (PF4) after complex formation with heparin or other polyanions. After antibody binding to PF4/heparin complexes, HIT antibodies are capable of intravascular platelet activation by cross-linking Fc gamma receptor IIa (FcγRIIa) on the platelet surface leading to a platelet count decrease and/or thrombosis. In contrast to most other immune-mediated disorders, the currently available laboratory tests for anti-PF4/heparin antibodies show a high sensitivity also for clinically irrelevant antibodies. This makes the diagnosis of HIT challenging and bears the risk to substantially overdiagnose HIT. The strength of the antigen assays for HIT is in ruling out HIT when the test is negative. Functional assays have a higher specificity for clinically relevant antibodies, but they are restricted to specialized laboratories. Currently, a Bayesian approach combining the clinical likelihood estimation for HIT with laboratory tests is the most appropriate approach to diagnose HIT. In this review, we give an overview on currently available diagnostic procedures and discuss their limitations. © 2014 John Wiley & Sons Ltd.

  9. Plasma exchange to remove HIT antibodies: dissociation between enzyme-immunoassay and platelet activation test reactivities.

    Science.gov (United States)

    Warkentin, Theodore E; Sheppard, Jo-Ann I; Chu, F Victor; Kapoor, Anil; Crowther, Mark A; Gangji, Azim

    2015-01-01

    Repeated therapeutic plasma exchange (TPE) has been advocated to remove heparin-induced thrombocytopenia (HIT) IgG antibodies before cardiac/vascular surgery in patients who have serologically-confirmed acute or subacute HIT; for this situation, a negative platelet activation assay (eg, platelet serotonin-release assay [SRA]) has been recommended as the target serological end point to permit safe surgery. We compared reactivities in the SRA and an anti-PF4/heparin IgG-specific enzyme immunoassay (EIA), testing serial serum samples in a patient with recent (subacute) HIT who underwent serial TPE precardiac surgery, as well as for 15 other serially-diluted HIT sera. We observed that post-TPE/diluted HIT sera-when first testing SRA-negative-continue to test strongly positive by EIA-IgG. This dissociation between the platelet activation assay and a PF4-dependent immunoassay for HIT antibodies indicates that patients with subacute HIT undergoing repeated TPE before heparin reexposure should be tested by serial platelet activation assays even when their EIAs remain strongly positive. © 2015 by The American Society of Hematology.

  10. Final Environmental Impact Statement of the Proposed Ground Based Free Electron Laser Technology Integration Experiment, White Sands Missile Range, New Mexico

    Science.gov (United States)

    1987-01-01

    Area E. School Site Area F. Stall1on Site Area 6. Hogge’s Knoll H. North Oscura Peak 1. Mockingbird Gap Area J. Three Rivers Area K. East of...include the northern mockingbird ; Chihuahuan raven; cactus, rock and Bewick’s wrens; curve-billed thrasher; loggerhead shrike; rufous-sided and brown...Those reptiles and amphibians hit directly by the laser beam or indirectly by backscattering or reflectance would be injured or killed . Lead and

  11. Lateral control strategy for a hypersonic cruise missile

    Directory of Open Access Journals (Sweden)

    Yonghua Fan

    2017-04-01

    Full Text Available Hypersonic cruise missile always adopts the configuration of waverider body with the restraint of scramjet. As a result, the lateral motion exhibits serious coupling, and the controller design of the lateral lateral system cannot be conducted separately for yaw channel and roll channel. A multiple input and multiple output optimal control method with integrators is presented to design the lateral combined control system for hypersonic cruise missile. A hypersonic cruise missile lateral model is linearized as a multiple input and multiple output plant, which is coupled by kinematics and fin deflection between yaw and roll. In lateral combined controller, the integrators are augmented, respectively, into the loop of roll angle and lateral overload to ensure that the commands are tracked with zero steady-state error. Through simulation, the proposed controller demonstrates good performance in tracking the command of roll angle and lateral overload.

  12. Constructive Technology Assessment for HIT development

    DEFF Research Database (Denmark)

    Høstgaard, Anna Marie Balling; Bertelsen, Pernille; Petersen, Lone Stub

    2013-01-01

    Experience and time has shown a need for new evaluation methods for evaluating Health Information Technology (HIT), as summative evaluation methods fail to accommodate the rapid and constant changes in HIT over time and to involve end-users, which has been recognized as an important success facto...... during all the phases in the process. Thereby anumber of problems were prevented to occur later on.Thus, the CTA method and its framework are useful for evaluators and project-management in order to facilitate and support successful HIT development....

  13. 75 FR 81589 - Notice of Advisory Committee Meeting Date Change

    Science.gov (United States)

    2010-12-28

    ... DEPARTMENT OF DEFENSE Office of the Secretary of Defense Notice of Advisory Committee Meeting Date Change AGENCY: Missile Defense Agency (MDA), DoD. ACTION: Notice. SUMMARY: On Tuesday, December 14, 2010... meetings of the Missile Defense [[Page 81590

  14. Liquid Missile Fuels as Means of Chemical Terrorist Attack

    International Nuclear Information System (INIS)

    Superina, V.; Orehovec, Z.

    2007-01-01

    Modern world is faced with numerous terrorist attacks whose goals, methods and means of the conduct are various. It seems that we have entered the era when terrorism, one's own little terrorism, is the easiest and the most painless way of achieving a goal. That is why that such a situation has contributed to the necessity for strengthening individual and collective protection and safety, import and export control, control of the production and illegal sale of the potential means for delivering terrorist act. It has also contributed to the necessity for devising means of the delivery. For more than 10 years, a series of congresses on CB MTS Industry has pointed at chemicals and chemical industry as potential means and targets of terrorism. The specialization and experience of different authors in the field of the missile technology and missile fuels, especially those of Eastern origin, and the threat that was the reality of the war conflicts in 1990s was the reason for making a scientific and expert analysis of the liquid missile fuels as means of terrorism. There are not many experts in the field of NBC protection who are familiar with the toxicity and reaction of liquid missile fuels still lying discarded and unprotected in abandoned barracks all over Europe and Asia. The purpose of this paper is to draw public attention to possible different abuses of liquid missile fuels for a terrorist purpose, as well as to possible consequences and prevention measures against such abuses. (author)

  15. From Attitudes to Actions: Predictors of Lion Killing by Maasai Warriors.

    Science.gov (United States)

    Hazzah, Leela; Bath, Alistair; Dolrenry, Stephanie; Dickman, Amy; Frank, Laurence

    2017-01-01

    Despite legal protection, deliberate killing by local people is one of the major threats to the conservation of lions and other large carnivores in Africa. Addressing this problem poses particular challenges, mainly because it is difficult to uncover illicit behavior. This article examined two groups of Maasai warriors: individuals who have killed African lions (Panthera leo) and those who have not. We conducted interviews to explore the relationship between attitudes, intentions and known lion killing behavior. Factor analysis and logistic regression revealed that lion killing was mainly determined by: (a) general attitudes toward lions, (b) engagement in traditional customs, (c) lion killing intentions to defend property, and (d) socio-cultural killing intentions. Our results indicated that general attitudes toward lions were the strongest predictor of lion killing behavior. Influencing attitudes to encourage pro-conservation behavior may help reduce killing.

  16. First evidence for slave rebellion: enslaved ant workers systematically kill the brood of their social parasite protomognathus americanus.

    Science.gov (United States)

    Achenbach, Alexandra; Foitzik, Susanne

    2009-04-01

    During the process of coevolution, social parasites have evolved sophisticated strategies to exploit the brood care behavior of their social hosts. Slave-making ant queens invade host colonies and kill or eject all adult host ants. Host workers, which eclose from the remaining brood, are tricked into caring for the parasite brood. Due to their high prevalence and frequent raids, following which stolen host broods are similarly enslaved, slave-making ants exert substantial selection upon their hosts, leading to the evolution of antiparasite adaptations. However, all host defenses shown to date are active before host workers are parasitized, whereas selection was thought to be unable to act on traits of already enslaved hosts. Yet, here we demonstrate the rebellion of enslaved Temnothorax workers, which kill two-thirds of the female pupae of the slave-making ant Protomognathus americanus. Thereby, slaves decrease the long-term parasite impact on surrounding related host colonies. This novel antiparasite strategy of enslaved workers constitutes a new level in the coevolutionary battle after host colony defense has failed. Our discovery is analogous to recent findings in hosts of avian brood parasites where perfect mimicry of parasite eggs leads to the evolution of chick recognition as a second line of defense.

  17. Nedley Depression Hit Hypothesis

    OpenAIRE

    Nedley, Neil; Ramirez, Francisco E.

    2014-01-01

    Depression is often diagnosed using the Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-5) criteria. We propose how certain lifestyle choices and non-modifiable factors can predict the development of depression. We identified 10 cause categories (hits or ?blows? to the brain) and theorize that four or more active hits could trigger a depression episode. Methods. A sample of 4271 participants from our community-based program (70% female; ages 17-94 years) was assessed ...

  18. Military and Security Developments Involving the People’s Republic of China 2011

    Science.gov (United States)

    2011-01-01

    cruise missile exhaust system capable of rendering a cruise missile resistant to detection by infrared missiles. In September 2010, Chi Tong Kuok was...for cooperation and competition. Speaking at the Shangri-la Dialogue in June 2010, then-Secretary of Defense Robert Gates asserted that the Defense

  19. FRAUD/SABOTAGE Killing Nuclear-Reactors!!! ``Super"alloys GENERIC ENDEMIC Wigner's-Disease IN-stability!!!

    Science.gov (United States)

    Asphahani, Aziz; Siegel, Sidney; Siegel, Edward

    2010-03-01

    Siegel [[J.Mag.Mag.Mtls.7,312(78); PSS(a)11,45(72); Semis.& Insuls.5(79)] (at: ORNL, ANS, Westin``KL"ouse, PSEG, IAEA, ABB) warning of old/new nuclear-reactors/spent-fuel-casks/refineries/ jet/missile/rocket-engines austenitic/FCC Ni/Fe-based (so MIS- called)``super"alloys(182/82;Hastelloy-X; 600;304/304L-SSs; 690 !!!) GENERIC ENDEMIC EXTANT detrimental(synonyms): Wigner's- diseas(WD)[J.Appl.Phys.17,857(46)]; Ostwald-ripening; spinodal- decomposition; overageing-embrittlement; thermomechanical- INstability: Mayo[Google: ``If Leaks Could Kill"; at flickr.com search on ``Giant-Magnotoresistance"; find: [SiegelPolitics(79)]; Hoffman[animatedsoftware.com],...what DOE/NRC MISlabels as ``butt-welds" ``stress-corrosion cracking" endpoint's ROOT-CAUSE ULTIMATE-ORIGIN is WD overageing-embrit- tlement caused brittle-fracture cracking from early/ongoing AEC/DOE-n``u''tional-la``v''atories sabotage!!!

  20. The Killing

    DEFF Research Database (Denmark)

    Agger, Gunhild

    2013-01-01

    This article tracks the uncanny locations of The Killing (2007–2012), relating them to place, space and atmosphere, putting bits and pieces from the topographic puzzle together with cues from the symbolic space in order to see how they fit into the overall pattern of Nordic Noir. In The Killing......, the abstract level of space and atmosphere meets the concrete level of place, both influencing the notion of location. This meeting, I suggest, has contributed towards the simultaneous domestic and international appeal of The Killing....

  1. Reinforced concrete behavior due to missile impact

    International Nuclear Information System (INIS)

    Alderson, M.A.H.G.; Bartley, R.; O'Brien, T.P.

    1977-01-01

    The assessment of the safety of nuclear reactors has necessitated the study of the effect of missiles on reinforced concrete containment structures. Two simple theoretical calculational methods have been developed to provide basic information. The first is based on a crude energy balance approach in which that part of the kinetic energy of the missile which is transferred into the containment structure, is absorbed only as bending strain energy. To determine the energy transferred into the structure it is assumed that during the loading the target does not respond. The energy input to the structure is thus equal to the kinetic energy it will possess immediately the impulse has been removed. The boundary of the responding zone is defined by the distance travelled by the shear stress wave during the time in which the impact force increases to the load at which the shear capacity reaches the ultimate shear resistance. The second method is based on the equation of motion for an equivalent one-degree-of-freedom system assuming that only the peak value of deflection is important and that damping can be ignored. The spring stiffness of the equivalent system has been based upon the stiffness of the actual disc configuration responding in the flexural mode only. The boundaries of the disc have been defined by using the elastic plate formulae and equating those positive and negative moments which will produce a specified yield line pattern which may be inferred from plastic plate formulae. The equation of motion is solved to indicate how the quantity of reinforcement included in the structure may modify the peak deflection. By limiting the ductility ratio of the reinforcement to some prescribed level it is possible to indicate the quantity of reinforcement w

  2. Russia and NATO Missile Defense: The European Phased Adaptive Approach Experience, 2009-2017

    Science.gov (United States)

    2018-03-01

    Volume I, 1945-1955. Ft. McNair, Washington, DC: US Army Center of Military History , 2009. Defense Science Board. Science and Technology Issues of...but were not the only contributing factors. Budgetary constraints, technological issues, and reassessments of threats also led to modifications in the...design for adaptability to benefit from technological innovations and to meet the evolving needs for Alliance protection in the international security

  3. FRAUD/SABOTAGE Killing Nuclear-Reactors Need Modeling!!!: "Super"alloys GENERIC ENDEMIC Wigner's-Disease/.../IN-stability: Ethics? SHMETHICS!!!

    Science.gov (United States)

    Asphahani, Aziz; Siegel, Sidney; Siegel, Edward

    2010-03-01

    Carbides solid-state chemistry domination of old/new nuclear- reactors/spent-fuel-casks/refineries/jet/missile/rocket-engines in austenitic/FCC Ni/Fe-based(so miscalled)``super"alloys(182/82; Hastelloy-X,600,304/304L-SSs,...,690!!!) GENERIC ENDEMIC EXTANT detrimental(synonyms): Wigner's-diseas(WD)[J.Appl.Phys.17,857 (1946)]/Ostwald-ripening/spinodal-decomposition/overageing- embrittlement/thermal-leading-to-mechanical(TLTM)-INstability: Mayo[Google:``If Leaks Could Kill"; at flickr.com search on ``Giant-Magnotoresistance"; find: Siegel[J.Mag.Mag.Mtls.7,312 (1978)]Politics(1979)]-Hoffman[animatedsoftware.com], what DOE/NRC MISlabels as ``butt-welds" ``stress-corrosion cracking" endpoint's ROOT-CAUSE ULTIMATE-ORIGIN is WD overageing-embritt- lement caused brittle-fracture cracking from early/ongoing AEC/ DOE-n"u"tional-la"v"atories sabotage!!!

  4. Health Information Technologies-Academic and Commercial Evaluation (HIT-ACE) methodology: description and application to clinical feedback systems.

    Science.gov (United States)

    Lyon, Aaron R; Lewis, Cara C; Melvin, Abigail; Boyd, Meredith; Nicodimos, Semret; Liu, Freda F; Jungbluth, Nathaniel

    2016-09-22

    Health information technologies (HIT) have become nearly ubiquitous in the contemporary healthcare landscape, but information about HIT development, functionality, and implementation readiness is frequently siloed. Theory-driven methods of compiling, evaluating, and integrating information from the academic and commercial sectors are necessary to guide stakeholder decision-making surrounding HIT adoption and to develop pragmatic HIT research agendas. This article presents the Health Information Technologies-Academic and Commercial Evaluation (HIT-ACE) methodology, a structured, theory-driven method for compiling and evaluating information from multiple sectors. As an example demonstration of the methodology, we apply HIT-ACE to mental and behavioral health measurement feedback systems (MFS). MFS are a specific class of HIT that support the implementation of routine outcome monitoring, an evidence-based practice. HIT-ACE is guided by theories and frameworks related to user-centered design and implementation science. The methodology involves four phases: (1) coding academic and commercial materials, (2) developer/purveyor interviews, (3) linking putative implementation mechanisms to hit capabilities, and (4) experimental testing of capabilities and mechanisms. In the current demonstration, phase 1 included a systematic process to identify MFS in mental and behavioral health using academic literature and commercial websites. Using user-centered design, implementation science, and feedback frameworks, the HIT-ACE coding system was developed, piloted, and used to review each identified system for the presence of 38 capabilities and 18 additional characteristics via a consensus coding process. Bibliometic data were also collected to examine the representation of the systems in the scientific literature. As an example, results are presented for the application of HIT-ACE phase 1 to MFS wherein 49 separate MFS were identified, reflecting a diverse array of characteristics

  5. Replica scaling studies of hard missile impacts on reinforced concrete

    International Nuclear Information System (INIS)

    Barr, P.; Carter, P.G.; Howe, W.D.; Neilson, A.J.

    1982-01-01

    Missile and target combinations at three different liners scales have been used in an experimental assessment of the applicability of replica scaling to the dynamic behaviour of reinforced concrete structures impacted by rigid missiles. Experimental results are presented for models with relative linear scales of 1, 0.37 and 0.12. (orig.) [de

  6. The role of strategic missile defence in the global architecture de ballistic non proliferation

    International Nuclear Information System (INIS)

    Hautecouverture, Benjamin

    2007-01-01

    Whereas some think that missile defence is a proliferation agent by nature and therefore undermines the already fragile regime of ballistic non proliferation, some others think that missile defence could underpin the non proliferation regime. The author thus discusses these issues and both points of view by commenting the ambiguous discursive relationships between missile defence and arms control, and by highlighting the various roles and missions given to missile defence, notably in treaties (like the ABM treaty) and postures adopted by concerned countries

  7. Simplified validation of borderline hits of database searches

    OpenAIRE

    Thomas, Henrik; Shevchenko, Andrej

    2008-01-01

    Along with unequivocal hits produced by matching multiple MS/MS spectra to database sequences, LC-MS/MS analysis often yields a large number of hits of borderline statistical confidence. To simplify their validation, we propose to use rapid de novo interpretation of all acquired MS/MS spectra and, with the help of a simple software tool, display the candidate sequences together with each database search hit. We demonstrate that comparing hit database sequences and independent de novo interpre...

  8. Acceleration effects on missile aerodynamics

    CSIR Research Space (South Africa)

    Gledhill, Irvy MA

    2010-09-01

    Full Text Available Practical requirements are now arising in which significant acceleration takes place during flight; 5th generation missiles, such as A-Darter, execute turns at 100 g, where g is the acceleration due to gravity, and thrust from propulsion systems may...

  9. 75 FR 59176 - DoD Mandatory Declassification Review (MDR) Program

    Science.gov (United States)

    2010-09-27

    ..., VA 22060-6201. (13) Missile Defense Agency. Missile Defense Agency, Attention: MDA/DS, 7100 Defense... DEPARTMENT OF DEFENSE Office of the Secretary 32 CFR Part 222 [DoD-2010-OS-0043; RIN 0790-AI62] DoD Mandatory Declassification Review (MDR) Program AGENCY: Department of Defense. ACTION: Proposed...

  10. Impact load time histories for viscoelastic missiles

    International Nuclear Information System (INIS)

    Stoykovich, M.

    1977-01-01

    Generation of the impact load time history at the contact point between a viscoelastic missile and its targets is presented. In the past, in the case of aircraft striking containment shell structure, the impact load time history was determined on the basis of actual measurements by subjecting a rigid wall to aircraft crash. The effects of elastic deformation of the target upon the impact load time history is formulated in this paper. The missile is idealized by a linear mass-spring-dashpot combination using viscoelastic models. These models can readily be processed taking into account the elastic as well as inelastic deformations of the missiles. The target is assumed to be either linearly elastic or rigid. In the case of the linearly elastic target, the normal mode theory is used to express the time-dependent displacements of the target which is simulated by lumped masses, elastic properties and dashpots in discrete parts. In the case of Maxwell viscoelastic model, the time-dependent displacements of the missile and the target are given in terms of the unknown impact load time history. This leads to an integral equation which may be solved by Laplace transformation. The normal mode theory is provided. The target structure may be composed of different materials with different components. Concrete and steel structural components have inherently different viscous friction damping properties. Hence, the equivalent modal damping depends on the degree of participation of these components in the modal response. An approximate rule for determining damping in any vibration mode by weighting the damping of each component according to the modal energy stored in each component is considered

  11. Histones as mediators of host defense, inflammation and thrombosis.

    Science.gov (United States)

    Hoeksema, Marloes; van Eijk, Martin; Haagsman, Henk P; Hartshorn, Kevan L

    2016-01-01

    Histones are known for their ability to bind to and regulate expression of DNA. However, histones are also present in cytoplasm and extracellular fluids where they serve host defense functions and promote inflammatory responses. Histones are a major component of neutrophil extracellular traps that contribute to bacterial killing but also to inflammatory injury. Histones can act as antimicrobial peptides and directly kill bacteria, fungi, parasites and viruses, in vitro and in a variety of animal hosts. In addition, histones can trigger inflammatory responses in some cases acting through Toll-like receptors or inflammasome pathways. Extracellular histones mediate organ injury (lung, liver), sepsis physiology, thrombocytopenia and thrombin generation and some proteins can bind histones and reduce these potentially harmful effects.

  12. 78 FR 29135 - HIT Standards Committee Advisory Meeting

    Science.gov (United States)

    2013-05-17

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting AGENCY: Office of...: HIT Standards Committee. General Function of the Committee: To provide recommendations to the National... Federal Health IT Strategic Plan, and in accordance with policies developed by the HIT Policy Committee...

  13. The Intercontinental Ballistic Missile and Post Cold War Deterrence

    Science.gov (United States)

    2010-02-17

    Bonnetain, Hugues and Philippe Mazzoni. " Histoire De Missiles...Le 1er GMS Du Plateau D’Albion." http://www.capcomespace.net/dossiers/espace_europeen...Mazzoni, " Histoire De Missiles...Le 1er GMS Du Plateau D’Albion," http://www.capcomespace.net/dossiers/espace_europeen/albion/; Ministère de la Défense

  14. Reduction of multiple hits in atom probe tomography

    International Nuclear Information System (INIS)

    Thuvander, Mattias; Kvist, Anders; Johnson, Lars J.S.; Weidow, Jonathan; Andrén, Hans-Olof

    2013-01-01

    The accuracy of compositional measurements using atom probe tomography is often reduced because some ions are not recorded when several ions hit the detector in close proximity to each other and within a very short time span. In some cases, for example in analysis of carbides, the multiple hits result in a preferential loss of certain elements, namely those elements that frequently field evaporate in bursts or as dissociating molecules. In this paper a method of reducing the effect of multiple hits is explored. A fine metal grid was mounted a few millimeters behind the local electrode, effectively functioning as a filter. This resulted in a decrease in the overall detection efficiency, from 37% to about 5%, but also in a decrease in the fraction of multiple hits. In an analysis of tungsten carbide the fraction of ions originating from multiple hits decreased from 46% to 10%. As a result, the measured carbon concentration increased from 48.2 at%to 49.8 at%, very close to the expected 50.0 at%. The characteristics of the multiple hits were compared for analyses with and without the grid filter. - Highlights: ► APT experiments have been performed with a reduced amount of multiple hits. ► The multiple hits were reduced by placing a grid behind the electrode. ► This resulted in improved carbon measurement of WC

  15. The Secret of Guided Missile Re-Entry,

    Science.gov (United States)

    1986-06-25

    I RD-PAI169 598 THE SECRET OF GUIDED MISSILE RE-ENTRY(U) FOREIGN / I TECHNOLOGY DIV NRIGHT-PATTERSON RFB OH J CHEN ET AL. I 25 JUN 96 FTD-ID(RS)T...TECHNOLOGY DIVISION THE SECRET OF GUIDED MISSILE RE-ENTRY by Chen Jingzhong, An Sehua J L 0 7 ’:;85’ ’ 0 *Approved for public release; Distribution...unlimite t d. :. 86 7 034.. FTD- ID(RS)T-0459-86 HUMAN TRANSLATION FTD-ID(RS)T-0459-86 25 June 1986 MICROFICHE NR: F - - 0Q 9? THE SECRET OF GUIDED

  16. Generation of missiles by tornadoes

    International Nuclear Information System (INIS)

    1974-11-01

    Available data on tornado wind velocities and wind distribution are incorporated into a mathematical model of the tornado wind field. The mathematical model is then used to predict the time-history of motion of a potential missile in a tornado wind field. (U.S.)

  17. 42 CFR 495.340 - As-needed HIT PAPD update and as-needed HIT IAPD update requirements.

    Science.gov (United States)

    2010-10-01

    ... limited to any of the following: (a) A projected cost increase of $100,000 or more. (b) A schedule... implementation approach, or scope of activities beyond that approved in the HIT planning advance planning document or the HIT implementation advance planning document. (d) A change in implementation concept or a...

  18. A modular ducted rocket missile model for threat and performance assessment

    NARCIS (Netherlands)

    Mayer, A.E.H.J.; Halswijk, W.H.C.; Komduur, H.J.; Lauzon, M.; Stowe, R.A.

    2005-01-01

    A model was developed to predict the thrust of throttled ramjet propelled missiles. The model is called DRCORE and fulfils the growing need to predict the performance of air breathing missiles. Each subsystem of the propulsion unit of this model is coded by using engineering formulae and enables the

  19. A laws of war review of contemporary land-based missile defence ...

    African Journals Online (AJOL)

    Automated precise guided missile defence has been around for some years, and is a modern-day mechanism used frequently since 2011 to defend against rocket attacks penetrating national airspace. Israel's automated Iron Dome Missile Defence System has intercepted over 1 000 rockets during two recent military ...

  20. Integrated defense system framework and high fidelity hardware-in-the-loop sensor stimulators

    Science.gov (United States)

    Buford, James A., Jr.; Barnett, Thomas C., Jr.; Vatz, Bernard W., II; Williams, M. Joshua; Van Bebber, James; Burson, Cliff

    2008-04-01

    The Strategic Defense Center of the U.S. Army Aviation and Missile Research, Development and Engineering Center (AMRDEC), System Simulation and Development Directorate (SS&DD) provides modeling and simulation (M&S) tools, providing medium and hi-fi sensor stimulation, and test control frameworks to evaluate performance of integrated defense systems. These systems include hardware and software representations provided by and operated by Service Program Offices or their representatives. The representations are geographically distributed, but linked together to provide a dynamic, real-time, interactive test environment that is centrally controlled and synchronized through Global Positioning System (GPS) sources. The distributed nodes and the central control facility communicate through the Single Stimulation Framework (SSF). Operation of the SSF provides characterization and assessment of the integrated defense systems. This paper will summarize the concept, features, and functions of the SSF. The complex communications will be discussed, as well as the philosophy of stimulating the participating system components externally with consistent scenarios and truth state data that will bypass the simulation of these events by the individual participants.

  1. Real-Time Target Motion Animation for Missile Warning System Testing

    Science.gov (United States)

    2006-04-01

    T. Perkins, R. Sundberg, J. Cordell, Z. Tun , and M. Owen, Real-time Target Motion Animation for Missile Warning System Testing, Proc. SPIE Vol 6208...Z39-18 Real-time target motion animation for missile warning system testing Timothy Perkins*a, Robert Sundberga, John Cordellb, Zaw Tunb, Mark

  2. An evaluation method for tornado missile strike probability with stochastic correction

    Energy Technology Data Exchange (ETDEWEB)

    Eguchi, Yuzuru; Murakami, Takahiro; Hirakuchi, Hiromaru; Sugimoto, Soichiro; Hattori, Yasuo [Nuclear Risk Research Center (External Natural Event Research Team), Central Research Institute of Electric Power Industry, Abiko (Japan)

    2017-03-15

    An efficient evaluation method for the probability of a tornado missile strike without using the Monte Carlo method is proposed in this paper. A major part of the proposed probability evaluation is based on numerical results computed using an in-house code, Tornado-borne missile analysis code, which enables us to evaluate the liftoff and flight behaviors of unconstrained objects on the ground driven by a tornado. Using the Tornado-borne missile analysis code, we can obtain a stochastic correlation between local wind speed and flight distance of each object, and this stochastic correlation is used to evaluate the conditional strike probability, QV(r), of a missile located at position r, where the local wind speed is V. In contrast, the annual exceedance probability of local wind speed, which can be computed using a tornado hazard analysis code, is used to derive the probability density function, p(V). Then, we finally obtain the annual probability of tornado missile strike on a structure with the convolutional integration of product of QV(r) and p(V) over V. The evaluation method is applied to a simple problem to qualitatively confirm the validity, and to quantitatively verify the results for two extreme cases in which an object is located just in the vicinity of or far away from the structure.

  3. An evaluation method for tornado missile strike probability with stochastic correction

    International Nuclear Information System (INIS)

    Eguchi, Yuzuru; Murakami, Takahiro; Hirakuchi, Hiromaru; Sugimoto, Soichiro; Hattori, Yasuo

    2017-01-01

    An efficient evaluation method for the probability of a tornado missile strike without using the Monte Carlo method is proposed in this paper. A major part of the proposed probability evaluation is based on numerical results computed using an in-house code, Tornado-borne missile analysis code, which enables us to evaluate the liftoff and flight behaviors of unconstrained objects on the ground driven by a tornado. Using the Tornado-borne missile analysis code, we can obtain a stochastic correlation between local wind speed and flight distance of each object, and this stochastic correlation is used to evaluate the conditional strike probability, QV(r), of a missile located at position r, where the local wind speed is V. In contrast, the annual exceedance probability of local wind speed, which can be computed using a tornado hazard analysis code, is used to derive the probability density function, p(V). Then, we finally obtain the annual probability of tornado missile strike on a structure with the convolutional integration of product of QV(r) and p(V) over V. The evaluation method is applied to a simple problem to qualitatively confirm the validity, and to quantitatively verify the results for two extreme cases in which an object is located just in the vicinity of or far away from the structure

  4. Flexible missile autopilot design studies with PC-MATLAB/386

    Science.gov (United States)

    Ruth, Michael J.

    1989-01-01

    Development of a responsive, high-bandwidth missile autopilot for airframes which have structural modes of unusually low frequency presents a challenging design task. Such systems are viable candidates for modern, state-space control design methods. The PC-MATLAB interactive software package provides an environment well-suited to the development of candidate linear control laws for flexible missile autopilots. The strengths of MATLAB include: (1) exceptionally high speed (MATLAB's version for 80386-based PC's offers benchmarks approaching minicomputer and mainframe performance); (2) ability to handle large design models of several hundred degrees of freedom, if necessary; and (3) broad extensibility through user-defined functions. To characterize MATLAB capabilities, a simplified design example is presented. This involves interactive definition of an observer-based state-space compensator for a flexible missile autopilot design task. MATLAB capabilities and limitations, in the context of this design task, are then summarized.

  5. Tornado missile simulation and design methodology. Volume 2: model verification and data base updates. Final report

    International Nuclear Information System (INIS)

    Twisdale, L.A.; Dunn, W.L.

    1981-08-01

    A probabilistic methodology has been developed to predict the probabilities of tornado-propelled missiles impacting and damaging nuclear power plant structures. Mathematical models of each event in the tornado missile hazard have been developed and sequenced to form an integrated, time-history simulation methodology. The models are data based where feasible. The data include documented records of tornado occurrence, field observations of missile transport, results of wind tunnel experiments, and missile impact tests. Probabilistic Monte Carlo techniques are used to estimate the risk probabilities. The methodology has been encoded in the TORMIS computer code to facilitate numerical analysis and plant-specific tornado missile probability assessments

  6. Novel HIT antibody detection method using Sonoclot® coagulation analyzer.

    Science.gov (United States)

    Wanaka, Keiko; Asada, Reiko; Miyashita, Kumiko; Kaneko, Makoto; Endo, Hirokazu; Yatomi, Yutaka

    2015-01-01

    Since heparin-induced thrombocytopenia (HIT), caused by the generation of antibodies against platelet factor 4 (PF4)/heparin complexes (HIT antibodies), may induce serious complications due to thrombosis, a prompt diagnosis is desirable. Functional tests with platelet activation to detect HIT antibodies are useful for diagnosis of HIT, in particular (14)C-selotonin release assay (SRA). However, they are complicated and so can be performed only in limited laboratories. We tested if a blood coagulation test using Sonoclot® analyzer can serve for the detection of HIT antibodies. A murine monoclonal antibody (HIT-MoAb) against PF4/heparin complexes was used as an alternative to human HIT antibodies. To the mixture of HIT-MoAb and heparin (0.5 U/mL, final), whole blood obtained from a healthy volunteer was added, and then the activated clotting time (ACT), clot rate (CR), and area under the curve (AUC) were measured with Sonoclot® analyzer for 30minutes. The HIT-MoAb (30 to 100μg/mL, final) concentration dependently suppressed the anticoagulation activity (prolongation of ACT and decrease of CR and AUC) of heparin. The suppression of anticoagulation effect of heparin by HIT-MoAb was demonstrated by measurements using Sonoclot® analyzer. This method may provide a new tool for screening of HIT antibodies. Copyright © 2014 Elsevier Ltd. All rights reserved.

  7. Conventional Prompt Global Strike and Long-Range Ballistic Missiles: Background and Issues

    Science.gov (United States)

    2016-02-24

    FY2008, Congress rejected the requested funding for this program, but the Navy has continued to consider the possibility of deploying intermediate ...10 Submarine-Launched Intermediate -Range Global Strike .................................................. 11 Air Force Programs...Missiles............................................................................ 36 Submarine-Launched Intermediate -Range Ballistic Missiles

  8. Implementation of a rapid HIT immunoassay at a university hospital - Retrospective analysis of HIT laboratory orders in patients with thrombocytopenia.

    Science.gov (United States)

    Black, Anne; Heimerl, Susanne; Oertli, Linnéa; Wilczek, Wolf; Greinacher, Andreas; Spannagl, Michael; Herr, Wolfgang; Hart, Christina

    2017-10-01

    Heparin-induced thrombocytopenia (HIT) is a rare cause of thrombocytopenia and a potentially life-threatening adverse drug reaction. Clinical overdiagnosis of HIT results in costly laboratory tests and anticoagulation. Criteria and algorithms for diagnosis are established, but their translation into clinical practice is still challenging. In a retrospective approach we studied all HIT related laboratory test requests within four years and evaluated data before (1st period, 24month) and after (2nd period, 24month) replacing particle gel immunoassay (PaGIA) and enzyme-linked immunosorbent assay (ELISA) by a chemiluminescent immunoassay (CLIA). HIT was confirmed by heparin-induced platelet activation (HIPA) test. Clinical pretest probability for HIT using an implemented simplified 4Ts score and platelet count were evaluated. Costs for laboratory tests and alternative anticoagulation were calculated. In 1850 patients with suspected HIT, 2327 laboratory orders were performed. In 87.2% of these orders an intermediate/high simplified 4Ts score was found. Thrombocytopenia was present in 87.1%. After replacing PaGIA and ELISA by CLIA the number of immunological and functional laboratory tests was reduced by 38.2%. The number of positive HIT immunoassays declined from 22.6% to 6.0%, while the number of positive HIPA tests among positive immunological tests increased by 19%. Altogether, acute HIT was confirmed in 59 patients. A decline in the use of alternative anticoagulants was observed in the 2nd period. Our study shows that in a university hospital setting HIT is well-known, but diagnosis requires a precise laboratory confirmation. Replacing PaGIA and ELISA by CLIA did not influence laboratory order behavior but results in reduced overall costs for laboratory diagnostics and alternative anticoagulation. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. The validation of Huffaz Intelligence Test (HIT)

    Science.gov (United States)

    Rahim, Mohd Azrin Mohammad; Ahmad, Tahir; Awang, Siti Rahmah; Safar, Ajmain

    2017-08-01

    In general, a hafiz who can memorize the Quran has many specialties especially in respect to their academic performances. In this study, the theory of multiple intelligences introduced by Howard Gardner is embedded in a developed psychometric instrument, namely Huffaz Intelligence Test (HIT). This paper presents the validation and the reliability of HIT of some tahfiz students in Malaysia Islamic schools. A pilot study was conducted involving 87 huffaz who were randomly selected to answer the items in HIT. The analysis method used includes Partial Least Square (PLS) on reliability, convergence and discriminant validation. The study has validated nine intelligences. The findings also indicated that the composite reliabilities for the nine types of intelligences are greater than 0.8. Thus, the HIT is a valid and reliable instrument to measure the multiple intelligences among huffaz.

  10. Local damage to reinforced concrete structures caused by impact of aircraft engine missiles. Pt. 2

    International Nuclear Information System (INIS)

    Sugano, T.; Tsubota, H.; Kasai, Y.; Koshika, N.; Itoh, C.; Shirai, K.; Von Riesemann, W.A.; Bickel, D.C.; Parks, M.B.

    1993-01-01

    Three sets of impact tests, small-, intermediate-, and full-scale tests, have been executed to determine local damage to reinforced concrete structures caused by the impact of aircraft engine missiles. The results of the test program showed that (1) the use of the similarity law is appropriate, (2) suitable empirical formulas exist for predicting the local damage caused by rigid missiles, (3) reduction factors may be used for evaluating the reduction in local damage due to the deformability of the engines, (4) the reinforcement ratio has no effect on local damage, and (5) the test results could be adequately predicted using nonlinear response analysis. (orig.)

  11. ARMS CONTROL: U.S. Efforts to Control the Transfer of Nuclear-Capable Missile Technology

    National Research Council Canada - National Science Library

    Plunkett, R

    1990-01-01

    ...). Through the MTCR, the United States and seven of its allies are attempting to limit the availability of certain systems, equipment, and technologies necessary for developing nuclear-capable missiles...

  12. The T10 beam produces a few hits per event. In ALICE the SSD will have to cope with many hits per strip. In the three centimeters of aluminium the beam will produce many secondary particles. This increases the chance of multiple hits per strip, although not to the level in ALICE.

    CERN Multimedia

    Nooren, G.

    2004-01-01

    The T10 beam produces a few hits per event. In ALICE the SSD will have to cope with many hits per strip. In the three centimeters of aluminium the beam will produce many secondary particles. This increases the chance of multiple hits per strip, although not to the level in ALICE.

  13. Managing Threat, Cost, and Incentive to Kill: The Short- and Long-Term Effects of Intervention in Mass Killings

    Science.gov (United States)

    Kathman, Jacob D.; Wood, Reed M.

    2011-01-01

    How do third-party interventions affect the severity of mass killings? The authors theorize that episodes of mass killing are the consequence of two factors: (1) the threat perceptions of the perpetrators and (2) the cost of implementing genocidal policies relative to other alternatives. To reduce genocidal hostilities, interveners must address…

  14. A Numerical Method for Blast Shock Wave Analysis of Missile Launch from Aircraft

    Directory of Open Access Journals (Sweden)

    Sebastian Heimbs

    2015-01-01

    Full Text Available An efficient empirical approach was developed to accurately represent the blast shock wave loading resulting from the launch of a missile from a military aircraft to be used in numerical analyses. Based on experimental test series of missile launches in laboratory environment and from a helicopter, equations were derived to predict the time- and position-dependent overpressure. The method was finally applied and validated in a structural analysis of a helicopter tail boom under missile launch shock wave loading.

  15. Historic American engineering record. Nevada national security site, Bren Tower Complex. Written historical and descriptive data and field records

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, Susan R. [Desert Research Institute, Las Vegas, NV (United States); Goldenberg, Nancy [Carey & Co Inc., San Francisco, CA (United States)

    2013-08-01

    The BREN (Bare Reactor Experiment, Nevada) Tower Complex is significant for its role in the history of nuclear testing, radiation dosimetry studies, and early field testing of the Strategic Missile Defense System designs. At the time it was built in 1962, the 1,527 ft (465 m) BREN Tower was the tallest structure west of the Mississippi River and exceeded the height of the Empire State Building by 55 ft (17 m). It remains the tallest ever erected specifically for scientific purposes and was designed and built to facilitate the experimental dosimetry studies necessary for the development of accurate radiation dose rates for the survivors of Hiroshima and Nagasaki. The tower was a key component of the Atomic Bomb Casualty Commission’s (ABCC) mission to predict the health effects of radiation exposure. Moved to its current location in 1966, the crucial dosimetry studies continued with Operation HENRE (High Energy Neutron Reactions Experiment). These experiments and the data they generated became the basis for a dosimetry system called the Tentative 1965 Dose or more commonly the T65D model. Used to estimate radiation doses received by individuals, the T65D model was applied until the mid-1980s when it was replaced by a new dosimetry system known as DS86 based on the Monte Carlo method of dose rate calculation. However, the BREN Tower data are still used for verification of the validity of the DS86 model. In addition to its importance in radiation heath effects research, the BREN Tower Complex is also significant for its role in the Brilliant Pebbles research project, a major component of the Strategic Defense Initiative popularly known as the “Star Wars” Initiative. Instigated under the Reagan Administration, the program’s purpose was to develop a system to shield the United States and allies from a ballistic missile attack. The centerpiece of the Strategic Defense System was space-based, kinetic-kill vehicles. In 1991, BREN Tower was used for the tether tests

  16. Noise Parameters of CW Radar Sensors Used in Active Defense Systems

    Directory of Open Access Journals (Sweden)

    V. Jenik

    2012-06-01

    Full Text Available Active defense represents an innovative way of protecting military vehicles. It is based on the employment of a set of radar sensors which detect an approaching threat missile and activate a suitable counter-measure. Since the radar sensors are supposed to detect flying missiles very fast and, at the same time, distinguish them from stationary or slow-moving objects, CW Doppler radar sensors can be employed with a benefit. The submitted article deals with a complex noise analysis of this type of sensors. The analysis considers the noise of linear and quasi-linear RF components, phase-noise of the local oscillator as well as the noise of low-frequency circuits. Since the incidence of the phase-noise depends strongly upon the time delay between the reference and the cross-talked signals, a new method of measuring noise parameters utilizing a reflecting wall has been developed and verified. The achieved results confirm potentially high influence of the phase-noise on the noise parameters of the mentioned type of radar sensors. Obtained results can be used for the analysis of noise parameters of the similar but even more complex sensors.

  17. Killing of targets by effector CD8 T cells in the mouse spleen follows the law of mass action

    Energy Technology Data Exchange (ETDEWEB)

    Ganusov, Vitaly V [Los Alamos National Laboratory

    2009-01-01

    In contrast with antibody-based vaccines, it has been difficult to measure the efficacy of T cell-based vaccines and to correlate the efficacy of CD8 T cell responses with protection again viral infections. In part, this difficulty is due to poor understanding of the in vivo efficacy of CD8 T cells produced by vaccination. Using a: recently developed experimental method of in vivo cytotoxicity we have investigated quantitative aspects of killing of peptide-pulsed targets by effector and memory CD8 T cells, specific to three epitopes of lymphocytic choriomeningitis virus (LCMV), in the mouse spleen. By analyzing data on killing of targets with varying number of epitope-specific effector and memory CD8 T cells, we find that killing of targets by effectors follows the law of mass-action, that is the death rate of peptide-pulsed targets is proportional to the frequency of CTLs in the spleen. In contrast, killing of targets by memory CD8 T cells does not follow the mass action law because the death rate of targets saturates at high frequencies of memory CD8 T cells. For both effector and memory cells, we also find little support for the killing term that includes the decrease of the death rate of targets with target cell density. Interestingly, our analysis suggests that at low CD8 T cell frequencies, memory CD8 T cells on the per capita basis are more efficient at killing peptide-pulsed targets than effectors, but at high frequencies, effectors are more efficient killers than memory T cells. Comparison of the estimated killing efficacy of effector T cells with the value that is predicted from theoretical physics and based on motility of T cells in lymphoid tissues, suggests that limiting step in the killing of peptide-pulsed targets is delivering the lethal hit and not finding the target. Our results thus form a basis for quantitative understanding of the process of killing of virus-infected cells by T cell responses in tissues and can be used to correlate the

  18. Killing Range

    Science.gov (United States)

    Asal, Victor; Rethemeyer, R. Karl; Horgan, John

    2015-01-01

    This paper presents an analysis of the Provisional Irish Republican Army's (PIRA) brigade level behavior during the Northern Ireland Conflict (1970-1998) and identifies the organizational factors that impact a brigade's lethality as measured via terrorist attacks. Key independent variables include levels of technical expertise, cadre age, counter-terrorism policies experienced, brigade size, and IED components and delivery methods. We find that technical expertise within a brigade allows for careful IED usage, which significantly minimizes civilian casualties (a specific strategic goal of PIRA) while increasing the ability to kill more high value targets with IEDs. Lethal counter-terrorism events also significantly affect a brigade's likelihood of killing both civilians and high-value targets but in different ways. Killing PIRA members significantly decreases IED fatalities but also significantly decreases the possibility of zero civilian IED-related deaths in a given year. Killing innocent Catholics in a Brigade's county significantly increases total and civilian IED fatalities. Together the results suggest the necessity to analyze dynamic situational variables that impact terrorist group behavior at the sub-unit level. PMID:25838603

  19. Six-degree-of-freedom missile simulation using the ADI AD 100 digital computer and ADSIM simulation language

    Science.gov (United States)

    Zwaanenburg, Koos

    1989-01-01

    The use of an AD 100 computer and the ADSIM language in the six-degree-of-freedom digital simulation of an air-to-ground missile is illustrated. The missile is launched from a moving platform, typically a helicopter, and is capable of striking a mobile target up to 10 kilometers away. The missile could be any tactical missile. The performance numbers of the AD 100 show that it is possible to implement a high performance missile model in a real-time simulation without the problems associated with an implementation on a general purpose computer using FORTRAN.

  20. Hit size effectiveness in relation to the microdosimetric site size

    International Nuclear Information System (INIS)

    Varma, M.N.; Wuu, C.S.; Zaider, M.

    1994-01-01

    This paper examines the effect of site size (that is, the diameter of the microdosimetric volume) on the hit size effectiveness function (HSEF), q(y), for several endpoints relevant in radiation protection. A Bayesian and maximum entropy approach is used to solve the integral equations that determine, given microdosimetric spectra and measured initial slopes, the function q(y). All microdosimetric spectra have been calculated de novo. The somewhat surprising conclusion of this analysis is that site size plays only a minor role in selecting the hit size effectiveness function q(y). It thus appears that practical means (e.g. conventional proportional counters) are already at hand to actually implement the HSEF as a radiation protection tool. (Author)

  1. Killing-Yano tensors, rank-2 Killing tensors, and conserved quantities in higher dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Krtous, Pavel [Institute of Theoretical Physics, Charles University, V Holesovickach 2, Prague (Czech Republic); Kubiznak, David [Institute of Theoretical Physics, Charles University, V Holesovickach 2, Prague (Czech Republic); Page, Don N. [Theoretical Physics Institute, University of Alberta, Edmonton T6G 2G7, Alberta (Canada); Frolov, Valeri P. [Theoretical Physics Institute, University of Alberta, Edmonton T6G 2G7, Alberta (Canada)

    2007-02-15

    From the metric and one Killing-Yano tensor of rank D-2 in any D-dimensional spacetime with such a principal Killing-Yano tensor, we show how to generate k = [(D+1)/2] Killing-Yano tensors, of rank D-2j for all 0 {<=} j {<=} k-1, and k rank-2 Killing tensors, giving k constants of geodesic motion that are in involution. For the example of the Kerr-NUT-AdS spacetime (hep-th/0604125) with its principal Killing-Yano tensor (gr-qc/0610144), these constants and the constants from the k Killing vectors give D independent constants in involution, making the geodesic motion completely integrable (hep-th/0611083). The constants of motion are also related to the constants recently obtained in the separation of the Hamilton-Jacobi and Klein-Gordon equations (hep-th/0611245)

  2. Killing-Yano tensors, rank-2 Killing tensors, and conserved quantities in higher dimensions

    International Nuclear Information System (INIS)

    Krtous, Pavel; Kubiznak, David; Page, Don N.; Frolov, Valeri P.

    2007-01-01

    From the metric and one Killing-Yano tensor of rank D-2 in any D-dimensional spacetime with such a principal Killing-Yano tensor, we show how to generate k = [(D+1)/2] Killing-Yano tensors, of rank D-2j for all 0 ≤ j ≤ k-1, and k rank-2 Killing tensors, giving k constants of geodesic motion that are in involution. For the example of the Kerr-NUT-AdS spacetime (hep-th/0604125) with its principal Killing-Yano tensor (gr-qc/0610144), these constants and the constants from the k Killing vectors give D independent constants in involution, making the geodesic motion completely integrable (hep-th/0611083). The constants of motion are also related to the constants recently obtained in the separation of the Hamilton-Jacobi and Klein-Gordon equations (hep-th/0611245)

  3. 33 CFR 117.801 - Newtown Creek, Dutch Kills, English Kills and their tributaries.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Newtown Creek, Dutch Kills, English Kills and their tributaries. 117.801 Section 117.801 Navigation and Navigable Waters COAST GUARD....801 Newtown Creek, Dutch Kills, English Kills and their tributaries. (a) The following requirements...

  4. The average number of alpha-particle hits to the cell nucleus required to eradicate a tumour cell population

    International Nuclear Information System (INIS)

    Roeske, John C; Stinchcomb, Thomas G

    2006-01-01

    Alpha-particle emitters are currently being considered for the treatment of micrometastatic disease. Based on in vitro studies, it has been speculated that only a few alpha-particle hits to the cell nucleus are considered lethal. However, such estimates do not consider the stochastic variations in the number of alpha-particle hits, energy deposited, or in the cell survival process itself. Using a tumour control probability (TCP) model for alpha-particle emitters, we derive an estimate of the average number of hits to the cell nucleus required to provide a high probability of eradicating a tumour cell population. In simulation studies, our results demonstrate that the average number of hits required to achieve a 90% TCP for 10 4 clonogenic cells ranges from 18 to 108. Those cells that have large cell nuclei, high radiosensitivities and alpha-particle emissions occurring primarily in the nuclei tended to require more hits. As the clinical implementation of alpha-particle emitters is considered, this type of analysis may be useful in interpreting clinical results and in designing treatment strategies to achieve a favourable therapeutic outcome. (note)

  5. Precession feature extraction of ballistic missile warhead with high velocity

    Science.gov (United States)

    Sun, Huixia

    2018-04-01

    This paper establishes the precession model of ballistic missile warhead, and derives the formulas of micro-Doppler frequency induced by the target with precession. In order to obtain micro-Doppler feature of ballistic missile warhead with precession, micro-Doppler bandwidth estimation algorithm, which avoids velocity compensation, is presented based on high-resolution time-frequency transform. The results of computer simulations confirm the effectiveness of the proposed method even with low signal-to-noise ratio.

  6. To kill a mockingbird robot

    NARCIS (Netherlands)

    Bartneck, C.; Verbunt, M.N.C.; Mubin, O.; Al Mahmud, A.

    2007-01-01

    Robots are being introduced in our society but their social status is still unclear. A critical issue is if the robot's exhibition of intelligent life-like behavior leads to the users' perception of animacy. The ultimate test for the life-likeness of a robot is to kill it. We therefore conducted an

  7. On the Hitting Probability of Max-Stable Processes

    OpenAIRE

    Hofmann, Martin

    2012-01-01

    The probability that a max-stable process {\\eta} in C[0, 1] with identical marginal distribution function F hits x \\in R with 0 < F (x) < 1 is the hitting probability of x. We show that the hitting probability is always positive, unless the components of {\\eta} are completely dependent. Moreover, we consider the event that the paths of standard MSP hit some x \\in R twice and we give a sufficient condition for a positive probability of this event.

  8. Mitochondrial Fragmentation in Aspergillus fumigatus as Early Marker of Granulocyte Killing Activity

    Science.gov (United States)

    Ruf, Dominik; Brantl, Victor; Wagener, Johannes

    2018-01-01

    The host's defense against invasive mold infections relies on diverse antimicrobial activities of innate immune cells. However, studying these mechanisms in vitro is complicated by the filamentous nature of such pathogens that typically form long, branched, multinucleated and compartmentalized hyphae. Here we describe a novel method that allows for the visualization and quantification of the antifungal killing activity exerted by human granulocytes against hyphae of the opportunistic pathogen Aspergillus fumigatus. The approach relies on the distinct impact of fungal cell death on the morphology of mitochondria that were visualized with green fluorescent protein (GFP). We show that oxidative stress induces complete fragmentation of the tubular mitochondrial network which correlates with cell death of affected hyphae. Live cell microscopy revealed a similar and non-reversible disruption of the mitochondrial morphology followed by fading of fluorescence in Aspergillus hyphae that were killed by human granulocytes. Quantitative microscopic analysis of fixed samples was subsequently used to estimate the antifungal activity. By utilizing this assay, we demonstrate that lipopolysaccharides as well as human serum significantly increase the killing efficacy of the granulocytes. Our results demonstrate that evaluation of the mitochondrial morphology can be utilized to assess the fungicidal activity of granulocytes against A. fumigatus hyphae. PMID:29868488

  9. In Defense of Deterrence. The Relevance, Morality and Cost-Effectiveness of Nuclear Weapons

    International Nuclear Information System (INIS)

    Tertrais, Bruno

    2011-10-01

    Since 1945, nuclear deterrence has been the target of continuous criticism on strategic, legal and moral grounds. But in the past five years, the renewed debate on nuclear disarmament has been accompanied by an increase in such criticism. Efforts led by four US statesmen, or the more radical 'Global Zero' movement, as well as various diplomatic initiatives, have been accompanied by a flurry of new, serious academic studies questioning the legitimacy of nuclear weapons. More than ever, nuclear deterrence is attacked by many, both on the 'Left' and on the 'Right'. To the traditional arguments related to the credibility, the legality or the morality of nuclear deterrence are now added two other factors. First, nuclear weapons, it is argued, have limited value vis-a-vis proliferation and terrorism, and such risks bolster the case for nuclear disarmament. Second, alternatives such as high-precision conventional means and missile defense are said to now be much more effective than they were in the past. What follows is an attempt to respond to those arguments and offer a proper defense of nuclear deterrence. It is essentially devoted to the most traditional and widely used form of nuclear deterrence, that is, deterrence through the threat of nuclear retaliation ('deterrence by punishment'). It begins with revisiting and addressing the two classic criticisms of nuclear deterrence: its validity as a war-prevention mechanism (Part One, 'Nuclear Deterrence Works'), and its legality as well as morality (Part Two, 'Nuclear Deterrence Is Neither Immoral Nor Illegal'). It then goes on to address criticisms which, without being entirely new, have gained in importance in recent years: first, the cost-effectiveness of nuclear deterrence, in particular vis-a-vis so-called possible alternatives such conventional deterrence and missile defense (Part Three, 'Nuclear Deterrence is Cost-Effective'); second, the validity of nuclear deterrence in the context of twenty-first century

  10. Health information technology knowledge and skills needed by HIT employers.

    Science.gov (United States)

    Fenton, S H; Gongora-Ferraez, M J; Joost, E

    2012-01-01

    To evaluate the health information technology (HIT) workforce knowledge and skills needed by HIT employers. Statewide face-to-face and online focus groups of identified HIT employer groups in Austin, Brownsville, College Station, Dallas, El Paso, Houston, Lubbock, San Antonio, and webinars for rural health and nursing informatics. HIT employers reported needing an HIT workforce with diverse knowledge and skills ranging from basic to advanced, while covering information technology, privacy and security, clinical practice, needs assessment, contract negotiation, and many other areas. Consistent themes were that employees needed to be able to learn on the job and must possess the ability to think critically and problem solve. Many employers wanted persons with technical skills, yet also the knowledge and understanding of healthcare operations. The HIT employer focus groups provided valuable insight into employee skills needed in this fast-growing field. Additionally, this information will be utilized to develop a statewide HIT workforce needs assessment survey.

  11. Shipborne Laser Beam Weapon System for Defence against Cruise Missiles

    OpenAIRE

    J.P. Dudeja; G.S. Kalsey

    2000-01-01

    Sea-skim~ing cruise missiles pose the greatest threat to a surface ship in the present-day war scenario. The convenitional close-in-weapon-systems (CIWSs) are becoming less reliable against these new challenges requiring extremely fast reaction time. Naval Forces see a high energy laser as a feasible andjeffective directed energy weapon against sea-skimming antiship cruise missiles becauseof its .ability to deliver destructive energy at the speed of light on to a distant target. The paper com...

  12. Evaluation of flow cytometric HIT assays in relation to an IgG-Specific immunoassay and clinical outcome.

    Science.gov (United States)

    Kerényi, Adrienne; Beke Debreceni, Ildikó; Oláh, Zsolt; Ilonczai, Péter; Bereczky, Zsuzsanna; Nagy, Béla; Muszbek, László; Kappelmayer, János

    2017-09-01

    Heparin-induced thrombocytopenia (HIT) is a severe side effect of heparin treatment caused by platelet activating IgG antibodies generated against the platelet factor 4 (PF4)-heparin complex. Thrombocytopenia and thrombosis are the leading clinical symptoms of HIT. The clinical pretest probability of HIT was evaluated by the 4T score system. Laboratory testing of HIT was performed by immunological detection of antibodies against PF4-heparin complex (EIA) and two functional assays. Heparin-dependent activation of donor platelets by patient plasma was detected by flow cytometry. Increased binding of Annexin-V to platelets and elevated number of platelet-derived microparticles (PMP) were the indicators of platelet activation. EIA for IgG isotype HIT antibodies was performed in 405 suspected HIT patients. Based on negative EIA results, HIT was excluded in 365 (90%) of cases. In 40 patients with positive EIA test result functional tests were performed. Platelet activating antibodies were detected in 17 cases by Annexin V binding. PMP count analysis provided nearly identical results. The probability of a positive flow cytometric assay result was higher in patients with elevated antibody titer. 71% of patients with positive EIA and functional assay had thrombosis. EIA is an important first line laboratory test in the diagnosis of HIT; however, HIT must be confirmed by a functional test. Annexin V binding and PMP assays using flow cytometry are functional HIT tests convenient in a clinical diagnostic laboratory. The positive results of functional assays may predict the onset of thrombosis. © 2016 International Clinical Cytometry Society. © 2016 International Clinical Cytometry Society.

  13. Full-scale turbine-missile concrete impact experiments. Final report

    International Nuclear Information System (INIS)

    Woodfin, R.L.

    1983-02-01

    Four full-scale experiments were conducted at Sandia National Laboratories' rocket sled facility to provide data on the response of reinforced concrete containment walls to impact and penetration by postulated turbine-produced missiles. The missiles' mass, velocity, and attitude, and the steel liner thickness, were varied. A 1476-kg, 120 0 segment cut from a shrunk-on turbine disc was used for three experiments, and a 2100-kg, 137 0 segment of another disc was used for one experiment. The targets were concrete panels fabricated of commercial ready-mix concrete of strength 24 to 28 MPa at 28 days and heavily reinforced (approx. = 5% by volume) with No. 18 (57-mm-dai) bars. Impacts were perpendicular to the targets at their centers. Three impacts were with the sharp corner of the missile forward (piercing) and one was with the rounded side forward (blunt). Rebar strains, liner strains, and rear face kinematic quantities were recorded for each test. Internal pressure pulses generated by the impacts were recorded on two tests. High-speed camera coverage was extensive. Depth of penetration was the primary measure diameter. Penetration depths into the 1.37-m-thick panels ranged from 33 cm for the blunt impact of the 1476-kg missile at 92 m/s to 65 cm for the piercing impact of the 2100-kg missile at 115m/s. Impact at the piercing attitude caused significantly more severe rear face cracking than did impact at the blunt attitude, but since rear face panel displacements in excess of 6 cm and velocities greater than 7 m/s were measured, results suggested that impact at a blunt attitude might cause scabbing at lower velocities than impact at a piercing attidude. In these tests, the presence of a 9.5-mm-thick steel liner on the rear face of the panel in the latter two tests precluded scabbing. Results also indicated that design formulas in common use give conservative results

  14. HIT or miss: the application of health care information technology to managing uncertainty in clinical decision making.

    Science.gov (United States)

    Kazandjian, Vahé A; Lipitz-Snyderman, Allison

    2011-12-01

    To discuss the usefulness of health care information technology (HIT) in assisting care providers minimize uncertainty while simultaneously increasing efficiency of the care provided. An ongoing study of HIT, performance measurement (clinical and production efficiency) and their implications to the payment for care represents the design of this study. Since 2006, all Maryland hospitals have embarked on a multi-faceted study of performance measures and HIT adoption surveys, which will shape the health care payment model in Maryland, the last of the all-payor states, in 2011. This paper focuses on the HIT component of the Maryland care payment initiative. While the payment model is still under review and discussion, 'appropriateness' of care has been discussed as an important dimension of measurement. Within this dimension, the 'uncertainty' concept has been identified as associated with variation in care practices. Hence, the methods of this paper define how HIT can assist care providers in addressing the concept of uncertainty, and then provides findings from the first HIT survey in Maryland to infer the readiness of Maryland hospital in addressing uncertainty of care in part through the use of HIT. Maryland hospitals show noteworthy variation in their adoption and use of HIT. While computerized, electronic patient records are not commonly used among and across Maryland hospitals, many of the uses of HIT internally in each hospital could significantly assist in better communication about better practices to minimize uncertainty of care and enhance the efficiency of its production. © 2010 Blackwell Publishing Ltd.

  15. Ionospheric disturbances induced by a missile launched from North Korea on 12 December 2012

    Science.gov (United States)

    Kakinami, Yoshihiro; Yamamoto, Masayuki; Chen, Chia-Hung; Watanabe, Shigeto; Lin, Charles; Liu, Jenn-Yanq; Habu, Hiroto

    2013-08-01

    disturbances caused by a missile launched from North Korea on 12 December 2012 were investigated by using the GPS total electron content (TEC). The spatial characteristic of the front edge of V-shaped disturbances produced by missiles and rockets was first determined. Considering the launch direction and the height of estimated ionospheric points at which GPS radio signal pierces the ionosphere, the missile passed through the ionosphere at heights of 391, 425, and 435 km at 0056:30, 0057:00, and 0057:30 UT, respectively. The observed velocities of the missile were 2.8 and 3.2 km/s at that time, which was estimated from the traveling speed of the front edge of V-shaped disturbances. Westward and eastward V-shaped disturbances propagated at 1.8-2.6 km/s. The phase velocities of the westward and eastward V-shaped disturbances were much faster than the speed of acoustic waves reported in previous studies, suggesting that sources other than acoustic waves may have played an important role. Furthermore, the plasma density depletion that is often observed following missile and rocket launches was not found. This suggests that the depletion resulting from the missile's exhaust was not strong enough to be observed in the TEC distribution in the topside ionosphere.

  16. A new method of passive counting of nuclear missile warheads -a white paper for the Defense Threat Reduction Agency

    Energy Technology Data Exchange (ETDEWEB)

    Morris, Christopher [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Durham, J. Matthew [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Guardincerri, Elena [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Bacon, Jeffrey Darnell [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Wang, Zhehui [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Fellows, Shelby [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Poulson, Daniel Cris [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Plaud-Ramos, Kenie Omar [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Daughton, Tess Marie [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Johnson, Olivia Ruth [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-07-31

    Cosmic ray muon imaging has been studied for the past several years as a possible technique for nuclear warhead inspection and verification as part of the New Strategic Arms Reduction Treaty between the United States and the Russian Federation. The Los Alamos team has studied two different muon imaging methods for this application, using detectors on two sides and one side of the object of interest. In this report we present results obtained on single sided imaging of configurations aimed at demonstrating the potential of this technique for counting nuclear warheads in place with detectors above the closed hatch of a ballistic missile submarine.

  17. Elimination of the Roll Bias Caused by Wrap Around Fins for the FMTI Missile

    National Research Council Canada - National Science Library

    McKerley, C

    1998-01-01

    The Future Missile Technology Integration (FMTI) Missile System is an attempt to design an Army tactical weapon that can effectively attack both fixed and rotary wing aircraft and armor of all types...

  18. Development process of muzzle flows including a gun-launched missile

    OpenAIRE

    Zhuo Changfei; Feng Feng; Wu Xiaosong

    2015-01-01

    Numerical investigations on the launch process of a gun-launched missile from the muzzle of a cannon to the free-flight stage have been performed in this paper. The dynamic overlapped grids approach are applied to dealing with the problems of a moving gun-launched missile. The high-resolution upwind scheme (AUSMPW+) and the detailed reaction kinetics model are adopted to solve the chemical non-equilibrium Euler equations for dynamic grids. The development process and flow field structure of m...

  19. Adragna Rebuttal to Morrison.

    Science.gov (United States)

    Adragna, Steven P.

    1985-01-01

    Morrison's critique of the Reagan Administration's Strategic Defense Initiative is representative of the views of those who oppose ballistic missile defense (Georgia Social Science Journal; v16 n2 p12-14 Spr 1985). Morrison's analysis is thoughtful, well structured, and well presented. However, it is quite wrong. Fallacies in his analysis are…

  20. A Simplified Procedure for Reliability Estimation of Underground Concrete Barriers against Normal Missile Impact

    Directory of Open Access Journals (Sweden)

    N. A. Siddiqui

    2011-06-01

    Full Text Available Underground concrete barriers are frequently used to protect strategic structures like Nuclear power plants (NPP, deep under the soil against any possible high velocity missile impact. For a given range and type of missile (or projectile it is of paramount importance to examine the reliability of underground concrete barriers under expected uncertainties involved in the missile, concrete, and soil parameters. In this paper, a simple procedure for the reliability assessment of underground concrete barriers against normal missile impact has been presented using the First Order Reliability Method (FORM. The presented procedure is illustrated by applying it to a concrete barrier that lies at a certain depth in the soil. Some parametric studies are also conducted to obtain the design values which make the barrier as reliable as desired.

  1. Escherichia coli K-12 pathogenicity in the pea aphid, Acyrthosiphon pisum, reveals reduced antibacterial defense in aphids.

    Science.gov (United States)

    Altincicek, Boran; Ter Braak, Bas; Laughton, Alice M; Udekwu, Klas I; Gerardo, Nicole M

    2011-10-01

    To better understand the molecular basis underlying aphid immune tolerance to beneficial bacteria and immune defense to pathogenic bacteria, we characterized how the pea aphid Acyrthosiphon pisum responds to Escherichia coli K-12 infections. E. coli bacteria, usually cleared in the hemolymph of other insect species, were capable of growing exponentially and killing aphids within a few days. Red fluorescence protein expressing E. coli K-12 laboratory strain multiplied in the aphid hemolymph as well as in the digestive tract, resulting in death of infected aphids. Selected gene deletion mutants of the E. coli K-12 predicted to have reduced virulence during systemic infections showed no difference in either replication or killing rate when compared to the wild type E. coli strain. Of note, however, the XL1-Blue E. coli K-12 strain exhibited a significant lag phase before multiplying and killing aphids. This bacterial strain has recently been shown to be more sensitive to oxidative stress than other E. coli K-12 strains, revealing a potential role for reactive oxygen species-mediated defenses in the otherwise reduced aphid immune system. Copyright © 2011 Elsevier Ltd. All rights reserved.

  2. Range Reference Atmosphere 0-70 Km Altitude. Kwajalein Missile Range, Kwajalein, Marshall Islands

    Science.gov (United States)

    1982-01-01

    DOCUMENT 360-82 KWAJALEIN MISSILE RANGE KWAJALEIN, MARSHALL ISLANDS RANGE REFERENCE ATMOSPHERE 0-70 KM ALTITUDE, C00 L’’I METEOROLOGY GROUP .RANGE...34Reference Atmosphere (Part 1), Kwajale 4n Missile Range, Kwajalein, Marshall Islands ," ADA002664. * 19. KEY WORDS (Continue on revorsae d. If necoeewy...CLASSIFICATION OF TIlS PAGE (Whe~n Data EnterecD -v DOCUMENT 360-82 Vo- KWAJALEIN MISSILE RANGE KWAJALEIN, MARSHALL ISLANDS RANGE REFERENCE ATMOSPHERE 0-70 km

  3. A Two-Hit Model of Autism: Adolescence as the Second Hit

    Science.gov (United States)

    Picci, Giorgia; Scherf, K. Suzanne

    2015-01-01

    Adolescence brings dramatic changes in behavior and neural organization. Unfortunately, for some 30% of individuals with autism, there is marked decline in adaptive functioning during adolescence. We propose a two-hit model of autism. First, early perturbations in neural development function as a “first hit” that sets up a neural system that is “built to fail” in the face of a second hit. Second, the confluence of pubertal hormones, neural reorganization, and increasing social demands during adolescence provides the “second hit” that interferes with the ability to transition into adult social roles and levels of adaptive functioning. In support of this model, we review evidence about adolescent-specific neural and behavioral development in autism. We conclude with predictions and recommendations for empirical investigation about several domains in which developmental trajectories for individuals with autism may be uniquely deterred in adolescence. PMID:26609500

  4. Hit-and-run, hit-and-stay, and commensal bacteria present different peptide content when viewed from the perspective of the T cell.

    Science.gov (United States)

    He, Lu; De Groot, Anne S; Bailey-Kellogg, Chris

    2015-11-27

    Different types of bacteria face different pressures from the immune system, with those that persist ("hit-and-stay") potentially having to adapt more in order to escape than those prone to short-lived infection ("hit-and-run"), and with commensal bacteria potentially different from both due to additional physical mechanisms for avoiding immune detection. The Janus Immunogenicity Score (JIS) was recently developed to assess the likelihood of T cell recognition of an antigen, using an analysis that considers both binding of a peptide within the antigen by major histocompatability complex (MHC) and recognition of the peptide:MHC complex by cognate T cell receptor (TCR). This score was shown to be predictive of T effector vs. T regulatory or null responses in experimental data, as well as to distinguish viruses representative of the hit-and-stay vs. hit-and-run phenotypes. Here, JIS-based analyses were conducted in order to characterize the extent to which the pressure to avoid T cell recognition is manifested in genomic differences among representative hit-and-run, hit-and-stay, and commensal bacteria. Overall, extracellular proteins were found to have different JIS profiles from cytoplasmic ones. Contrasting the bacterial groups, extracellular proteins were shown to be quite different across the groups, much more so than intracellular proteins. The differences were evident even at the level of corresponding peptides in homologous protein pairs from hit-and-run and hit-and-stay bacteria. The multi-level analysis of patterns of immunogenicity across different groups of bacteria provides a new way to approach questions of bacterial immune camouflage or escape, as well as to approach the selection and optimization of candidates for vaccine design. Copyright © 2015 Elsevier Ltd. All rights reserved.

  5. 77 FR 64564 - Implementation of Regulatory Guide 1.221 on Design-Basis Hurricane and Hurricane Missiles

    Science.gov (United States)

    2012-10-22

    ...-Basis Hurricane and Hurricane Missiles AGENCY: Nuclear Regulatory Commission. ACTION: Proposed interim...-ISG-024, ``Implementation of Regulatory Guide 1.221 on Design-Basis Hurricane and Hurricane Missiles....221, ``Design-Basis Hurricane and Hurricane Missiles for Nuclear Power Plants.'' DATES: Submit...

  6. Cloning, killing, and identity.

    Science.gov (United States)

    McMahan, J

    1999-01-01

    One potentially valuable use of cloning is to provide a source of tissues or organs for transplantation. The most important objection to this use of cloning is that a human clone would be the sort of entity that it would be seriously wrong to kill. I argue that entities of the sort that you and I essentially are do not begin to exist until around the seventh month of fetal gestation. Therefore to kill a clone prior to that would not be to kill someone like you or me but would be only to prevent one of us from existing. And even after one of us begins to exist, the objections to killing it remain comparatively weak until its psychological capacities reach a certain level of maturation. These claims support the permissibility of killing a clone during the early stages of its development in order to use its organs for transplantation. PMID:10226909

  7. Standard Missile-6 (SM-6)

    Science.gov (United States)

    2016-12-01

    attack or Anti-Ship Cruise Missiles in flight. The SM-6 ERAM program is an evolutionary, capabilities based acquisition program that will use spiral ...Prior SAR Total O&S Estimates - Dec 2014 SAR 460.3 Programmatic/Planning Factors 0.0 Cost Estimating Methodology 0.0 Cost Data Update 0.0 Labor Rate

  8. Missile impacts as sources of seismic energy on the moon

    Science.gov (United States)

    Latham, G.V.; McDonald, W.G.; Moore, H.J.

    1970-01-01

    Seismic signals recorded from impacts of missiles at the White Sands Missile Range are radically different from the signal recorded from the Apollo 12 lunar module impact. This implies that lunar structure to depths of at least 10 to 20 kilometers is quite different from the typical structure of the earth's crust. Results obtained from this study can be used to predict seismic wave amplitudes from future man-made lunar impacts. Seismic energy and crater dimensions from impacts are compared with measurements from chemical explosions.

  9. Do pigeons prefer alternatives that include near-hit outcomes?

    Science.gov (United States)

    Stagner, Jessica P; Case, Jacob P; Sticklen, Mary F; Duncan, Amanda K; Zentall, Thomas R

    2015-07-01

    Pigeons show suboptimal choice on a gambling-like task similar to that shown by humans. Humans also show a preference for gambles in which there are near hits (losses that come close to winning). In the present research, we asked if pigeons would show a preference for alternatives with near-hit-like trials. In Experiment 1, we included an alternative that presented a near hit, in which a stimulus associated with reinforcement (a presumed conditioned reinforcer) changed to a stimulus associated with the absence of reinforcement (a presumed conditioned inhibitor). The pigeons tended to avoid this alternative. In Experiment 2, we varied the duration of the presumed conditioned reinforcer (2 vs. 8 s) that changed to a presumed conditioned inhibitor (8 vs. 2 s) and found that the longer the conditioned reinforcer was presented, the more the pigeons avoided it. In Experiment 3, the near-hit alternative involved an ambiguous stimulus for 8 s that changed to a presumed conditioned reinforcer (or a presumed conditioned inhibitor) for 2 s, but the pigeons still avoided it. In Experiment 4, we controlled for the duration of the conditioned reinforcer by presenting it first for 2 s followed by the ambiguous stimulus for 8 s. Once again, the pigeons avoided the alternative with the near-hit trials. In all 4 experiments, the pigeons tended to avoid alternatives that provided near-hit-like trials. We concluded that humans may be attracted to near-hit trials because near-hit trials give them the illusion of control, whereas this does not appear to be a factor for pigeons. (c) 2015 APA, all rights reserved).

  10. Morrison Rebuttal to Adragna.

    Science.gov (United States)

    Morrison, David C.

    1985-01-01

    Steven Adragna's arguments for a space-based ballistic missile defense (Georgia Social Science Journal; v16 n2 p14-16 Spr 1985) are founded on the High Frontier organization's usual distortions of the historical record, coupled with a wildly optimistic technological euphoria shared by few of even the Strategic Defense Initiative's most ardent…

  11. 76 FR 46297 - HIT Standards Committee's Workgroup Meetings; Notice of Meetings

    Science.gov (United States)

    2011-08-02

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee's Workgroup Meetings; Notice of... be open to the public via dial-in access only. Name of Committees: HIT Standards Committee's... developed by the HIT Policy Committee. Date and Time: The HIT Standards Committee Workgroups will hold the...

  12. Is There an Association Between Heparin-Induced Thrombocytopenia (HIT) and Autoimmune Disease?

    Science.gov (United States)

    Klinkhammer, Brent; Gruchalla, Michael

    2018-03-01

    Heparin-induced thrombocytopenia (HIT) is a drug-induced, immunoglobulin G medicated autoimmune disorder associated with several negative clinical outcomes including increased morbidity, mortality, and increased medical costs. Previous studies have shown associations between comorbid autoimmune diseases, but there is little known about associations between HIT and autoimmunity. To provide clinical data to suggest an association between HIT and autoimmunity. Retrospective chart review of 59 cases with a diagnosis of HIT and 251 matched controls without a HIT diagnosis, comparing the prevalence of autoimmunity in each group. A single, large upper Midwest health care system. Patients with a diagnosis of HIT were significantly more likely to have a comorbid autoimmune disease than those without a HIT diagnosis (55.9% vs 10.8%, P HIT were significantly more likely to have a diagnosis of antiphospholipid syndrome (15.3% vs 0.0%, P HIT were significantly older than controls ( P HIT and autoimmune disease and suggests a need for more research into the relationship between HIT and autoimmunity. These results could alter the anticoagulation management of venous thromboembolism and acute coronary syndrome in patients with a previously identified autoimmune disease. Copyright© Wisconsin Medical Society.

  13. Marine Biological Survey, Peacock Point Outfall, Wake Atoll June 1998 (NODC Accession 0000247)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The U.S. Army Space and Missile Defense Command (SMDC), in support of the Ballistic Missile Defense Organization (BMDO) sponsored a marine biological survey at Wake...

  14. Baseline marine biological survey at the Peacock Point outfall and other point-source discharges on Wake Atoll, Pacific Ocean in 1998-06 (NODC Accession 0000247)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The U.S. Army Space and Missile Defense Command (SMDC) in support of the Ballistic Missile Defense Organization (BMDO) sponsored a marine biological survey at Wake...

  15. Combined hit theory-microdosimetric explanation of cellular radiobiological action

    International Nuclear Information System (INIS)

    Bond, V.P.; Varma, M.N.

    1983-01-01

    Hit theory is combined with microdosimetry in a stochastic approach that explains the observed responses of cell populations exposed in radiation fields of different qualities. The central thesis is that to expose a population of cells in a low-level radiation field is to subject the cells to the potential for interaction with charged particles in the vicinity of the cells, quantifiable in terms of the charged particle fluence theta. When such an interaction occurs there is a resulting stochastic transfer of energy to a critical volume (CV) of cross section sigma, within the cell(s). The severity of cell injury is dependent on the amount of energy thus imparted, or the hit size. If the severity is above some minimal level, there is a non-zero probability that the injury will result in a quantal effect (e.g., a mutational or carcinogenic initial event, cell transformation). A microdosimetric proportional counter, viewed here as a phantom cell CV that permits measurements not possible in the living cell, is used to determine the incidence of hit cells and the spectrum of hit sizes. Each hit is then weighted on the basis of an empirically-determined function that provides the fraction of cells responding quantally, as a function of hit size. The sum of the hits so weighted provides the incidence of quantally-responding cells, for any amount of exposure theta in a radiation field of any quality or mixture qualities. The hit size weighting function for pink mutations in Tradescantia is discussed, as are its implications in terms of a replacement for RBE and dose equivalent. 14 references, 9 figures

  16. Development of the IFJ single ion hit facility for cells irradiation

    International Nuclear Information System (INIS)

    Veselov, O.; Polak, W.; Ugenskiene, R.; Hajduk, R.; Lebed, K.; Lekki, J.; Horwacik, T.; Dutkiewicz, E.M.; Maranda, S.; Pieprzyca, T.; Sarnecki, C.; Stachura, Z.; Szklarz, Z.; Styczen, J.

    2005-12-01

    In recent years a single ion hit facility (SIHF) has been constructed at the IFJ ion microprobe. The setup is used for the precise irradiations of living cells by a controlled number of ions. The facility allows investigations in various aspects of biomedical research, such as adaptive response, bystander effect, inverse dose-rate effect, low-dose hypersensitivity, etc. Those investigations have two very important requirements: (i) cells must be examined in their natural state and environment, i.e. without previously being killed, and preferentially, neither fixed nor stained, and (ii) a possibility of automatic irradiation of large number of cells with a computer recognition of their positions must be provided. This work presents some of the crucial features of the off-line and on-line optical systems, including self-developed software responsible for the automatic cell recognition. We also show several tests carried out to determine the efficiency of the whole setup and some segments. In conclusion, the results of our first irradiation measurements performed with living cells are demonstrated. (author)

  17. Risk assessment methodology for extreme wind and missile effects on critical facilities

    International Nuclear Information System (INIS)

    Twisdale, L.A.; Dunn, W.L.

    1985-01-01

    The TORMIS methodology has been applied to a number of probabilistic risk assessments of critical facilities in the continental United States. These analyses have centered on the estimation of tornado missile impact and damage risks to individual targets as well as to groups of targets at specific plants. A number of advancements and generalizations in the approach have recently been made. These include: (1) generalization of windfield options to include straight winds (WINMIS) and hurricanes (HURMIS); (2) generalization of the scoring to enable analysis of Boolean system expressions for damage probabilities on compound series and parallel safety trains; (3) generalization of the failure criteria to include wind pressure as well as missile impact; (4) generalization of the plant modeling capability to enable more detailed treatment of targets partially or fully enclosed by vulnerable cladding and to allow tracking of missiles inside such enclosures; and (5) incorporation of windspeed criteria for structural failure and subsequent production of potential missiles. This paper will present some of the basic theory and key results of recent TORMIS, WINMIS, and HURMIS applications. The influence of uncertainties in the estimation process and the data needed for plant-specific risk assessments will also be discussed

  18. Analysing the Wrongness of Killing

    DEFF Research Database (Denmark)

    Di Nucci, Ezio

    2014-01-01

    This article provides an in-depth analysis of the wrongness of killing by comparing different versions of three influential views: the traditional view that killing is always wrong; the liberal view that killing is wrong if and only if the victim does not want to be killed; and Don Marquis‟ future...... of value account of the wrongness of killing. In particular, I illustrate the advantages that a basic version of the liberal view and a basic version of the future of value account have over competing alternatives. Still, ultimately none of the views analysed here are satisfactory; but the different...

  19. Navy Needs to Establish Effective Metrics to Achieve Desired Outcomes for SPY1 Radar Sustainment (Redacted)

    Science.gov (United States)

    2016-08-01

    subsystems in the AEGIS Weapon System that searches, detects, and tracks air and surface targets to support Anti -Air Warfare and Ballistic Missile... System that searches, detects, and tracks air and surface targets to support Anti -Air Warfare and Ballistic Missile Defense missions. The SPY-1 radar...a series on SPY-1 radar spare parts. The SPY-1 radar is an advanced, automatic detect and track radar system . The SPY-1 radar is one of 13 major

  20. Synthetic Medicinal Chemistry in Chagas' Disease: Compounds at The Final Stage of "Hit-To-Lead" Phase.

    Science.gov (United States)

    Cerecetto, Hugo; González, Mercedes

    2010-03-25

    Chagas' disease, or American trypanosomosiasis, has been the most relevant illness produced by protozoa in Latin America. Synthetic medicinal chemistry efforts have provided an extensive number of chemodiverse hits at the "active-to-hit" stage. However, only a more limited number of these have been studied in vivo in models of Chagas' disease. Herein, we survey some of the cantidates able to surpass the "hit-to-lead" stage discussing their limitations or merit to enter in clinical trials in the short term.

  1. How to kill creativity.

    Science.gov (United States)

    Amabile, T M

    1998-01-01

    In today's knowledge economy, creativity is more important than ever. But many companies unwittingly employ managerial practices that kill it. How? By crushing their employees' intrinsic motivation--the strong internal desire to do something based on interests and passions. Managers don't kill creativity on purpose. Yet in the pursuit of productivity, efficiency, and control--all worthy business imperatives--they undermine creativity. It doesn't have to be that way, says Teresa Amabile. Business imperatives can comfortably coexist with creativity. But managers will have to change their thinking first. Specifically, managers will need to understand that creativity has three parts: expertise, the ability to think flexibly and imaginatively, and motivation. Managers can influence the first two, but doing so is costly and slow. It would be far more effective to increase employees' intrinsic motivation. To that end, managers have five levers to pull: the amount of challenge they give employees, the degree of freedom they grant around process, the way they design work groups, the level of encouragement they give, and the nature of organizational support. Take challenge as an example. Intrinsic motivation is high when employees feel challenged but not overwhelmed by their work. The task for managers, therefore, becomes matching people to the right assignments. Consider also freedom. Intrinsic motivation--and thus creativity--soars when managers let people decide how to achieve goals, not what goals to achieve. Managers can make a difference when it comes to employee creativity. The result can be truly innovative companies in which creativity doesn't just survive but actually thrives.

  2. Plasma response to sustainment with imposed-dynamo current drive in HIT-SI and HIT-SI3

    Science.gov (United States)

    Hossack, A. C.; Jarboe, T. R.; Chandra, R. N.; Morgan, K. D.; Sutherland, D. A.; Penna, J. M.; Everson, C. J.; Nelson, B. A.

    2017-07-01

    The helicity injected torus—steady inductive (HIT-SI) program studies efficient, steady-state current drive for magnetic confinement plasmas using a novel experimental method. Stable, high-beta spheromaks have been sustained using steady, inductive current drive. Externally induced loop voltage and magnetic flux are oscillated together so that helicity and power injection are always positive, sustaining the edge plasma current indefinitely. Imposed-dynamo current drive (IDCD) theory further shows that the entire plasma current is sustained. The method is ideal for low aspect ratio, toroidal geometries with closed flux surfaces. Experimental studies of spheromak plasmas sustained with IDCD have shown stable magnetic profiles with evidence of pressure confinement. New measurements show coherent motion of a stable spheromak in response to the imposed perturbations. On the original device two helicity injectors were mounted on either side of the spheromak and the injected mode spectrum was predominantly n  =  1. Coherent, rigid motion indicates that the spheromak is stable and a lack of plasma-generated n  =  1 energy indicates that the maximum q is maintained below 1 during sustainment. Results from the HIT-SI3 device are also presented. Three inductive helicity injectors are mounted on one side of the spheromak flux conserver. Varying the relative injector phasing changes the injected mode spectrum which includes n  =  2, 3, and higher modes.

  3. A cardinal role for cathepsin d in co-ordinating the host-mediated apoptosis of macrophages and killing of pneumococci.

    Directory of Open Access Journals (Sweden)

    Martin A Bewley

    2011-01-01

    Full Text Available The bactericidal function of macrophages against pneumococci is enhanced by their apoptotic demise, which is controlled by the anti-apoptotic protein Mcl-1. Here, we show that lysosomal membrane permeabilization (LMP and cytosolic translocation of activated cathepsin D occur prior to activation of a mitochondrial pathway of macrophage apoptosis. Pharmacological inhibition or knockout of cathepsin D during pneumococcal infection blocked macrophage apoptosis. As a result of cathepsin D activation, Mcl-1 interacted with its ubiquitin ligase Mule and expression declined. Inhibition of cathepsin D had no effect on early bacterial killing but inhibited the late phase of apoptosis-associated killing of pneumococci in vitro. Mice bearing a cathepsin D(-/- hematopoietic system demonstrated reduced macrophage apoptosis in vivo, with decreased clearance of pneumococci and enhanced recruitment of neutrophils to control pulmonary infection. These findings establish an unexpected role for a cathepsin D-mediated lysosomal pathway of apoptosis in pulmonary host defense and underscore the importance of apoptosis-associated microbial killing to macrophage function.

  4. Fired missile projectiles

    International Nuclear Information System (INIS)

    Williams, K.D.; Gieszl, R.; Keller, P.J.; Drayer, B.P.

    1989-01-01

    This paper reports ferromagnetic properties of fired missile projectiles (bullets, BBs, etc) investigated. Projectile samples were obtained from manufactures, police, and commercial sources. Deflection measurements at the portal of a 1.5-T magnetic field were performed for 47 projectiles. Sixteen bullets were examined in gelatin phantoms for rotation-translation movements as well. Ferromagnetic bullets displayed considerable deflection forces in the presence of the magnetic field and could be rotated to 80 degrees from their previous alignments when introduced perpendicular to the magnetic field in our gelatin phantom experiments. Military bullet calibers appear to pose the greatest ferromagnetic risk. Commercial sporting ammunition is generally nonferromagnetic

  5. Overview of the HIT-SI3 spheromak experiment

    Science.gov (United States)

    Hossack, A. C.; Jarboe, T. R.; Chandra, R. N.; Morgan, K. D.; Sutherland, D. A.; Everson, C. J.; Penna, J. M.; Nelson, B. A.

    2017-10-01

    The HIT-SI and HIT-SI3 spheromak experiments (a = 23 cm) study efficient, steady-state current drive for magnetic confinement plasmas using a novel method which is ideal for low aspect ratio, toroidal geometries. Sustained spheromaks show coherent, imposed plasma motion and low plasma-generated mode activity, indicating stability. Analysis of surface magnetic fields in HIT-SI indicates large n = 0 and 1 mode amplitudes and little energy in higher modes. Within measurement uncertainties all the n = 1 energy is imposed by the injectors, rather than being plasma-generated. The fluctuating field imposed by the injectors is sufficient to sustain the toroidal current through dynamo action whereas the plasma-generated field is not (Hossack et al., Phys. Plasmas, 2017). Ion Doppler spectroscopy shows coherent, imposed plasma motion inside r 10 cm in HIT-SI and a smaller volume of coherent motion in HIT-SI3. Coherent motion indicates the spheromak is stable and a lack of plasma-generated n = 1 energy indicates the maximum q is maintained below 1 for stability during sustainment. In HIT-SI3, the imposed mode structure is varied to test the plasma response (Hossack et al., Nucl. Fusion, 2017). Imposing n = 2, n = 3, or large, rotating n = 1 perturbations is correlated with transient plasma-generated activity. Work supported by the U.S. Department of Energy, Office of Science, Office of Fusion Energy Sciences, under Award Number DE-FG02-96ER54361.

  6. Creating a safe place for pediatric care: A no hit zone.

    Science.gov (United States)

    Frazier, Erin R; Liu, Gilbert C; Dauk, Kelly L

    2014-07-01

    Our goal was to create and implement a program, Kosair Children's Hospital's No Hit Zone, which trains health care workers in de-escalation techniques to address parental disruptive behaviors and physical discipline of children commonly encountered in the hospital environment. The Child Abuse Task Force, a multidisciplinary group, along with key hospital administrators developed specific content for the policy, as well as marketing and educational materials. The No Hit Zone policy designates Kosair Children's Hospital as "an environment in which no adult shall hit a child, no adult shall hit another adult, no child shall hit an adult, and no child shall hit another child. When hitting is observed, it is everyone's responsibility to interrupt the behavior as well as communicate system policy to those present." Via a multidisciplinary, collaborative approach, the No Hit Zone was successfully implemented at Kosair Children's Hospital in 2012. Cost was nominal, and the support of key hospital administrators was critical to the program's success. Education of health professionals on de-escalation techniques and intervention with families at the early signs of parental stress occurred via live sessions and online training via case-based scenarios. The No Hit Zone is an important program used to provide a safe and caring environment for all families and staff of Kosair Children's Hospital. Demand for the program continues, demonstrated by the establishment of No Hit Zones at other local hospitals and multiple outpatient clinics. This article offers information for other organizations planning to conduct similar initiatives. Copyright © 2014 by the American Academy of Pediatrics.

  7. Family Violence in Domestic Homicides: A Case Study of Women Who Killed Intimate Partners Post-Legislative Reform in Victoria, Australia.

    Science.gov (United States)

    Tyson, Danielle; Kirkwood, Deborah; Mckenzie, Mandy

    2016-05-18

    This article examines the impact of legislative reforms enacted in 2005 in Victoria, Australia, on legal responses to women charged with murder for killing their intimate partner. The reforms provided for a broader understanding of the context of family violence to be considered in such cases, but we found little evidence of this in practice. This is partly attributable to persistent misconceptions among the legal profession about family violence and why women may believe it necessary to kill a partner. We recommend specialized training for legal professionals and increased use of family violence evidence to help ensure women's claims of self-defense receive appropriate responses from Victorian courts. © The Author(s) 2016.

  8. HIT and brain reward function: A case of mistaken identity (theory).

    Science.gov (United States)

    Wright, Cory; Colombo, Matteo; Beard, Alexander

    2017-08-01

    This paper employs a case study from the history of neuroscience-brain reward function-to scrutinize the inductive argument for the so-called 'Heuristic Identity Theory' (HIT). The case fails to support HIT, illustrating why other case studies previously thought to provide empirical support for HIT also fold under scrutiny. After distinguishing two different ways of understanding the types of identity claims presupposed by HIT and considering other conceptual problems, we conclude that HIT is not an alternative to the traditional identity theory so much as a relabeling of previously discussed strategies for mechanistic discovery. Copyright © 2017. Published by Elsevier Ltd.

  9. Hit-size effectiveness theory applied to high doses of low LET radiation for pink mutations in Tradescantia

    International Nuclear Information System (INIS)

    Varma, M.N.; Bond, V.P.; Matthews, G.

    1985-01-01

    A hit-size effectiveness function which represents the probability of inducing a pink mutation in Tradescantia as a function of lineal energy density has been obtained (1) using observed pink mutation data for seven different radiation qualities and their respective single event microdosimetric spectra. In obtaining this function only the linear portions of dose-response curves were used. A significant improvement of the concepts embodied in the proposed hit-size effectiveness theory would be the demonstration of its applicability at high doses (where multiple hits are produced) and high dose rates (at which no significant biological repair takes place). In this article details are given on preliminary calculations of the pink mutation frequency in Tradescantia at 1, 5, 10, 20, and 60 rads for 250 kVp x rays, using the multi-hit spectra and the hit-size effectiveness function obtained on the basis of single hit microdosimetric spectra as outline in (1). A comparison of the calculated and observed pink mutation frequencies indicate excellent agreement and suggests the possibility of obtaining the hit-size effectiveness function from high dose biological-effect data obtained using low-LET radiations. 6 refs., 3 figs., 3 tabs

  10. Design and Analysis of Megawatt Class Free Electron Laser Weapons

    Science.gov (United States)

    2015-12-01

    amplifier, FEL modeling, atmospheric propagation modeling 15. NUMBER OF PAGES 93 16. PRICE CODE 17. SECURITY CLASSIFICATION OF REPORT Unclassified 18...METRICS We define the target of interest as a sea skimming anti-ship missile. To achieve a hard-kill, we assume that the laser needs to melt a hole... skimming anti-ship missiles where achieving a hard kill in a matter of a couple of seconds is critical. However, for softer and slower moving targets

  11. De Nederlandse missile defence capaciteit: Strategisch onmisbaar

    NARCIS (Netherlands)

    Weimar, P.W.L.

    2013-01-01

    Surface based air & missile defence behelst enerzijds de verdediging tegen conventionele luchtdreigingen, zoals vliegtuigen, helikopters en onbemande vliegtuigen (luchtverdediging). Aan de andere kant houdt het de verdediging tegen ballistische raketten en kruisraketten in (raketverdediging). De

  12. Water-Exit Process Modeling and Added-Mass Calculation of the Submarine-Launched Missile

    Directory of Open Access Journals (Sweden)

    Yang Jian

    2017-11-01

    Full Text Available In the process that the submarine-launched missile exits the water, there is the complex fluid solid coupling phenomenon. Therefore, it is difficult to establish the accurate water-exit dynamic model. In the paper, according to the characteristics of the water-exit motion, based on the traditional method of added mass, considering the added mass changing rate, the water-exit dynamic model is established. And with help of the CFX fluid simulation software, a new calculation method of the added mass that is suit for submarine-launched missile is proposed, which can effectively solve the problem of fluid solid coupling in modeling process. Then by the new calculation method, the change law of the added mass in water-exit process of the missile is obtained. In simulated analysis, for the water-exit process of the missile, by comparing the results of the numerical simulation and the calculation of theoretical model, the effectiveness of the new added mass calculation method and the accuracy of the water-exit dynamic model that considers the added mass changing rate are verified.

  13. 75 FR 21629 - HIT Standards Committee's Workgroup Meetings; Notice of Meetings

    Science.gov (United States)

    2010-04-26

    ... Technology; HIT Standards Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National... only. Name of Committees: HIT Standards Committee's Workgroups: Clinical Operations Vocabulary... developed by the HIT Policy Committee. Date and Time: The HIT Standards Committee Workgroups will hold the...

  14. 77 FR 66617 - HIT Policy and Standards Committees; Workgroup Application Database

    Science.gov (United States)

    2012-11-06

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy and Standards Committees; Workgroup Application... of New ONC HIT FACA Workgroup Application Database. The Office of the National Coordinator (ONC) has.... Name of Committees: HIT Standards Committee and HIT Policy Committee. General Function of the...

  15. Tornado missile simulation and design methodology. Volume 1: simulation methodology, design applications, and TORMIS computer code. Final report

    International Nuclear Information System (INIS)

    Twisdale, L.A.; Dunn, W.L.

    1981-08-01

    A probabilistic methodology has been developed to predict the probabilities of tornado-propelled missiles impacting and damaging nuclear power plant structures. Mathematical models of each event in the tornado missile hazard have been developed and sequenced to form an integrated, time-history simulation methodology. The models are data based where feasible. The data include documented records of tornado occurrence, field observations of missile transport, results of wind tunnel experiments, and missile impact tests. Probabilistic Monte Carlo techniques are used to estimate the risk probabilities. The methodology has been encoded in the TORMIS computer code to facilitate numerical analysis and plant-specific tornado missile probability assessments. Sensitivity analyses have been performed on both the individual models and the integrated methodology, and risk has been assessed for a hypothetical nuclear power plant design case study

  16. A combined hit theory-microdosimetric explanation of cellular radiobiological action

    International Nuclear Information System (INIS)

    Bond, V.P.; Varma, M.N.

    1983-01-01

    Hit theory is combined with microdosimetry in a stochastic approach that explains the observed responses of cell populations exposed in radiation fields of different qualities. The central thesis is that to expose a population of cells in a low-level radiation field is to subject the cells to the potential for interaction with charged particles, quantifiable in terms of the charged particle fluence PHI. When such an interaction occurs there is resulting stochastic transfer of energy to a critical volume (CV) of cross-section σ within the cell(s). The severity of cell injury is dependent on the amount of energy thus imparted, or the hit size. If the severity is above some minimal level, there is a non-zero probability that the injury will result in a quantal effect (e.g., a mutational or carcinogenic initial event, cell transformation). A microdosimetric proportional counter, viewed here as a phantom cell CV that permits measurements not possible in the living cell, is used to determine the incidence of hit cells and the spectrum of hit sizes. Each hit is then weighted on the basis of an empirically determined function that provides the fraction of cells responding quantally, as a function of hit size. The sum of the hits so weighted provides the incidence of quantally responding cells, for any amount of exposure PHI in a radiation field of any quality or mixture of qualities. The hit size weighting function for pink mutations in Tradescantia is discussed, as are its implications in terms of a replacement for relative biological effectiveness and dose equivalent. (author)

  17. CT analysis of missile head injury

    International Nuclear Information System (INIS)

    Besenski, N.; Jadro-Santel, D.; Jelavic-Koic, F.; Pavic, D.; Mikulic, D.; Glavina, K.; Maskovic, J.

    1995-01-01

    Between August 1991 and December 1992, CT was performed in 154 patients who had suffered missile head injury during the war in the Republic of Croatia. In 54% CT was performed 1-24 h after injury, and in 27% follow-up CT was also obtained. The wounds were penetrating, tangential or perforating (45%, 34% and 21%, respectively). Haemorrhage was the most frequent lesion in the brain (84%). Follow-up CT evolution of haemorrhage, oedema, cerebritis, abscess, secondary vascular lesions, necrosis, encephalomalacia and hydrocephalus. The most dynamic changes occurred 7-14 days after injury. In 14% of cases, deep cerebral lesions were found in the corpus callosum, septum pellucidum periventricular region and pons, although bone and shell fragments were in a different part of the brain parenchyma. Such lesions were found in penetrating injuries only. CT proved very useful for assessing the extent and type of lesions. Although different mechanisms of brain damage in missile head injury are known, here they are, to the best of our knowledge, shown for the first time by CT. (orig.)

  18. 33 CFR 334.1130 - Pacific Ocean, Western Space and Missile Center (WSMC), Vandenberg AFB, Calif.; danger zones.

    Science.gov (United States)

    2010-07-01

    ... Missile Center (WSMC), Vandenberg AFB, Calif.; danger zones. 334.1130 Section 334.1130 Navigation and... RESTRICTED AREA REGULATIONS § 334.1130 Pacific Ocean, Western Space and Missile Center (WSMC), Vandenberg AFB... (WSMC) at Vandenberg AFB, California. (3) The impacting of missile debris from launch operations will...

  19. Identification of Pseudomonas aeruginosa phenazines that kill Caenorhabditis elegans.

    Science.gov (United States)

    Cezairliyan, Brent; Vinayavekhin, Nawaporn; Grenfell-Lee, Daniel; Yuen, Grace J; Saghatelian, Alan; Ausubel, Frederick M

    2013-01-01

    Pathogenic microbes employ a variety of methods to overcome host defenses, including the production and dispersal of molecules that are toxic to their hosts. Pseudomonas aeruginosa, a Gram-negative bacterium, is a pathogen of a diverse variety of hosts including mammals and the nematode Caenorhabditis elegans. In this study, we identify three small molecules in the phenazine class that are produced by P. aeruginosa strain PA14 that are toxic to C. elegans. We demonstrate that 1-hydroxyphenazine, phenazine-1-carboxylic acid, and pyocyanin are capable of killing nematodes in a matter of hours. 1-hydroxyphenazine is toxic over a wide pH range, whereas the toxicities of phenazine-1-carboxylic acid and pyocyanin are pH-dependent at non-overlapping pH ranges. We found that acidification of the growth medium by PA14 activates the toxicity of phenazine-1-carboxylic acid, which is the primary toxic agent towards C. elegans in our assay. Pyocyanin is not toxic under acidic conditions and 1-hydroxyphenazine is produced at concentrations too low to kill C. elegans. These results suggest a role for phenazine-1-carboxylic acid in mammalian pathogenesis because PA14 mutants deficient in phenazine production have been shown to be defective in pathogenesis in mice. More generally, these data demonstrate how diversity within a class of metabolites could affect bacterial toxicity in different environmental niches.

  20. Identification of Pseudomonas aeruginosa phenazines that kill Caenorhabditis elegans.

    Directory of Open Access Journals (Sweden)

    Brent Cezairliyan

    2013-01-01

    Full Text Available Pathogenic microbes employ a variety of methods to overcome host defenses, including the production and dispersal of molecules that are toxic to their hosts. Pseudomonas aeruginosa, a Gram-negative bacterium, is a pathogen of a diverse variety of hosts including mammals and the nematode Caenorhabditis elegans. In this study, we identify three small molecules in the phenazine class that are produced by P. aeruginosa strain PA14 that are toxic to C. elegans. We demonstrate that 1-hydroxyphenazine, phenazine-1-carboxylic acid, and pyocyanin are capable of killing nematodes in a matter of hours. 1-hydroxyphenazine is toxic over a wide pH range, whereas the toxicities of phenazine-1-carboxylic acid and pyocyanin are pH-dependent at non-overlapping pH ranges. We found that acidification of the growth medium by PA14 activates the toxicity of phenazine-1-carboxylic acid, which is the primary toxic agent towards C. elegans in our assay. Pyocyanin is not toxic under acidic conditions and 1-hydroxyphenazine is produced at concentrations too low to kill C. elegans. These results suggest a role for phenazine-1-carboxylic acid in mammalian pathogenesis because PA14 mutants deficient in phenazine production have been shown to be defective in pathogenesis in mice. More generally, these data demonstrate how diversity within a class of metabolites could affect bacterial toxicity in different environmental niches.

  1. PageRank, HITS and a unified framework for link analysis

    Energy Technology Data Exchange (ETDEWEB)

    Ding, Chris; He, Xiaofeng; Husbands, Parry; Zha, Hongyuan; Simon, Horst

    2001-10-01

    Two popular webpage ranking algorithms are HITS and PageRank. HITS emphasizes mutual reinforcement between authority and hub webpages, while PageRank emphasizes hyperlink weight normalization and web surfing based on random walk models. We systematically generalize/combine these concepts into a unified framework. The ranking framework contains a large algorithm space; HITS and PageRank are two extreme ends in this space. We study several normalized ranking algorithms which are intermediate between HITS and PageRank, and obtain closed-form solutions. We show that, to first order approximation, all ranking algorithms in this framework, including PageRank and HITS, lead to same ranking which is highly correlated with ranking by indegree. These results support the notion that in web resource ranking indegree and outdegree are of fundamental importance. Rankings of webgraphs of different sizes and queries are presented to illustrate our analysis.

  2. The three-hit concept of vulnerability and resilience: toward understanding adaptation to early-life adversity outcome.

    Science.gov (United States)

    Daskalakis, Nikolaos P; Bagot, Rosemary C; Parker, Karen J; Vinkers, Christiaan H; de Kloet, E R

    2013-09-01

    Stressful experiences during early-life can modulate the genetic programming of specific brain circuits underlying emotional and cognitive aspects of behavioral adaptation to stressful experiences later in life. Although this programming effect exerted by experience-related factors is an important determinant of mental health, its outcome depends on cognitive inputs and hence the valence an individual assigns to a given environmental context. From this perspective we will highlight, with studies in rodents, non-human primates and humans, the three-hit concept of vulnerability and resilience to stress-related mental disorders, which is based on gene-environment interactions during critical phases of perinatal and juvenile brain development. The three-hit (i.e., hit-1: genetic predisposition, hit-2: early-life environment, and hit-3: later-life environment) concept accommodates the cumulative stress hypothesis stating that in a given context vulnerability is enhanced when failure to cope with adversity accumulates. Alternatively, the concept also points to the individual's predictive adaptive capacity, which underlies the stress inoculation and match/mismatch hypotheses. The latter hypotheses propose that the experience of relatively mild early-life adversity prepares for the future and promotes resilience to similar challenges in later-life; when a mismatch occurs between early and later-life experience, coping is compromised and vulnerability is enhanced. The three-hit concept is fundamental for understanding how individuals can either be prepared for coping with life to come and remain resilient or are unable to do so and succumb to a stress-related mental disorder, under seemingly identical circumstances. Copyright © 2013 Elsevier Ltd. All rights reserved.

  3. "The Killing Fields" of Innovation

    DEFF Research Database (Denmark)

    Ingerslev, Karen

    2014-01-01

    to clustering of ideas, a design strategy which seemed to kill unique ideas. The reframing of innovation as a radical endeavor killed learning from others for being not innovative. The findings of this paper supplement theories of deliberate killing of ideas by suggesting framing, design and facilitation......This paper points to seemingly contradicted processes of framing innovation, idea generation and killing ideas. It reports from a yearlong innovation project, where health care professionals explored problems and tested ideas for solutions, regarding a future downsizing of the case hospital....... Theories in various ways describe the opening and closing phases of innovation. Exploration and idea generation opens a field of interest, which is then closed by making choices of ideas to further explore in the next opening phase. These choices deliberately kill a lot of ideas. In the innovation project...

  4. Modelling cavitating flow around underwater missiles

    Directory of Open Access Journals (Sweden)

    Fabien Petitpas

    2011-12-01

    Full Text Available The diffuse interface model of Saurel et al. (2008 is used for the computation of compressible cavitating flows around underwater missiles. Such systems use gas injection and natural cavitation to reduce drag effects. Consequently material interfaces appear separating liquid and gas. These interfaces may have a really complex dynamics such that only a few formulations are able to predict their evolution. Contrarily to front tracking or interface reconstruction method the interfaces are computed as diffused numerical zones, that are captured in a routinely manner, as is done usually with gas dynamics solvers for shocks and contact discontinuity. With the present approach, a single set of partial differential equations is solved everywhere, with a single numerical scheme. This leads to very efficient solvers. The algorithm derived in Saurel et al. (2009 is used to compute cavitation pockets around solid bodies. It is first validated against experiments done in cavitation tunnel at CNU. Then it is used to compute flows around high speed underwater systems (Shkval-like missile. Performance data are then computed showing method ability to predict forces acting on the system.

  5. Experimental studies on local damage of reinforced concrete structures by the impact of deformable missiles-Part 1

    International Nuclear Information System (INIS)

    Muto, K.; Tachikawa, H.; Sugano, T.; Tsubota, H.; Kobayshi, H.; Kasai, Y.; Koshika, N.; Tsujimoto, T.

    1989-01-01

    Structural damage induced by an accidental aircraft crash into a reinforced concrete structure includes local damage caused by the engine, the rigid portion of the aircraft, and the global elasto-plastic structural response caused by the entire aircraft. Local damage consists of spalling of concrete from the front face of the target together with missile penetration into the target, scabbing of concrete from the rear face of the target and perforation of the missile through the target. The engine is a soft missile that deforms during impact. An experimental research program has been planned and executed to establish a rational evaluation method of the local damage by the deformable engine missiles

  6. Missile Defense: Actions Needed to Improve Planning and Cost Estimates for Long-Term Support of Ballistic Missile Defense

    National Research Council Canada - National Science Library

    2008-01-01

    .... Since the cost to operate and support a weapon system usually accounts for most of a system's lifetime costs, the resources needed to fund BMDS could be significant as DOD fields an increasing number of BMDS elements...

  7. Slender body treatment of some specialized problems associated with elliptic-cross-section missile configurations

    Science.gov (United States)

    Barger, R. L.

    1977-01-01

    Slender body methods were applied to some specialized problems associated with missile configurations with elliptic cross sections. Expressions are derived for computing the velocity distribution on the nose section when the ellipse eccentricity is varying longitudinally on the missile. The cross flow velocity on a triform fin section is also studied.

  8. The Unsinkable Aircraft Carrier: An American Response to the Chinese Anti-Access/Area Denial (A2/AD) Challenge

    Science.gov (United States)

    2013-04-01

    Graduation Requirements Advisor: Dr. Jeffrey M. Reilly Maxwell Air Force Base, Alabama April 2013 DISTRIBUTION A. Approved for public release... Distribution unlimited Maj. John O. Birkeland CDOS Research Paper CDOS Seminar 1 ii Disclaimer The views expressed on this...Battalion-71 st Artillery to Taiwan with the new Nike -Hercules missile batteries. 121 The idea of an active defense against missiles has been

  9. Assessing the lipophilicity of fragments and early hits

    Science.gov (United States)

    Mortenson, Paul N.; Murray, Christopher W.

    2011-07-01

    A key challenge in many drug discovery programs is to accurately assess the potential value of screening hits. This is particularly true in fragment-based drug design (FBDD), where the hits often bind relatively weakly, but are correspondingly small. Ligand efficiency (LE) considers both the potency and the size of the molecule, and enables us to estimate whether or not an initial hit is likely to be optimisable to a potent, druglike lead. While size is a key property that needs to be controlled in a small molecule drug, there are a number of additional properties that should also be considered. Lipophilicity is amongst the most important of these additional properties, and here we present a new efficiency index (LLEAT) that combines lipophilicity, size and potency. The index is intuitively defined, and has been designed to have the same target value and dynamic range as LE, making it easily interpretable by medicinal chemists. Monitoring both LE and LLEAT should help both in the selection of more promising fragment hits, and controlling molecular weight and lipophilicity during optimisation.

  10. 76 FR 55914 - HIT Policy Committee's Workgroup Meetings; Notice of Meetings

    Science.gov (United States)

    2011-09-09

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee's Workgroup Meetings; Notice of... be open to the public via dial-in access only. Name of Committees: HIT Policy Committee's Workgroups... standards, implementation specifications, and certification criteria are needed. Date and Time: The HIT...

  11. 76 FR 46297 - HIT Policy Committee's Workgroup Meetings; Notice of Meetings

    Science.gov (United States)

    2011-08-02

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee's Workgroup Meetings; Notice of... be open to the public via dial-in access only. Name of Committees: HIT Policy Committee's Workgroups... standards, implementation specifications, and certification criteria are needed. Date and Time: The HIT...

  12. 76 FR 22399 - HIT Policy Committee's Workgroup Meetings; Notice of Meetings

    Science.gov (United States)

    2011-04-21

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee's Workgroup Meetings; Notice of... be open to the public via dial-in access only. Name of Committees: HIT Policy Committee's Workgroups... standards, implementation specifications, and certification criteria are needed. Date and Time: The HIT...

  13. 76 FR 28784 - HIT Policy Committee's Workgroup Meetings; Notice of Meetings

    Science.gov (United States)

    2011-05-18

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee's Workgroup Meetings; Notice of... be open to the public via dial-in access only. Name of Committees: HIT Policy Committee's Workgroups... standards, implementation specifications, and certification criteria are needed. Date and Time: The HIT...

  14. 76 FR 14974 - HIT Policy Committee's Workgroup Meetings; Notice of Meetings

    Science.gov (United States)

    2011-03-18

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee's Workgroup Meetings; Notice of... be open to the public via dial-in access only. Name of Committees: HIT Policy Committee's Workgroups... standards, implementation specifications, and certification criteria are needed. Date and Time: The HIT...

  15. 76 FR 50735 - HIT Policy Committee's Workgroup Meetings; Notice of Meetings

    Science.gov (United States)

    2011-08-16

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee's Workgroup Meetings; Notice of... be open to the public via dial-in access only. Name of Committees: HIT Policy Committee's Workgroups... standards, implementation specifications, and certification criteria are needed. Date and Time: The HIT...

  16. Dictionary of Missile and Artillery Terms

    Science.gov (United States)

    1982-05-20

    missile and projectile control. Remote control is used widely in military affairs. TEMPERATURA VSPYShKI VZRYVChATYKh VEShchESTV (Explosive Flash Point... TEMPERATURA GORENIYa POROKhA [Powder Combustion Temperature] (T 1 ) -. combustion (formation) temperature of powder computed from 00 K (absolute scale...234 // TEMPERATURA OBYChNOGO VZRYVA [Normal Burst Temperature] - maximum temperature to which gaseous products are heated during the explosion of a

  17. Defense Acquisition Research Journal. Volume 23, Number 3, Issue 78, July 2016

    Science.gov (United States)

    2016-07-01

    Gansler University of Maryland RADM James Greene, USN (Ret.) Naval Postgraduate School Dr. Mike Kotzian Defense Acquisition University Dr. Craig Lush...environment included Taliban attacks that killed or injured workers and destroyed equipment (Aff leck, Seman, Deegan , Freeman, & Sargand, 2011...transaction cost analysis dimensions: Do contract types differ? Journal of Applied Business Research, 15, 65–80. Affleck, R., Seman, P., Deegan , M

  18. Assessment of Containment Structures Against Missile Impact Threats

    Institute of Scientific and Technical Information of China (English)

    LI Q M

    2006-01-01

    In order to ensure the highest safety requirements,nuclear power plant structures (the containment structures,the fuel storages and transportation systems) should be assessed against all possible internal and external impact threats.The internal impact threats include kinetic missiles generated by the failure of high pressure vessels and pipes,the failure of high speed rotating machineries and accidental drops.The external impact threats may come from airborne missiles,aircraft impact,explosion blast and fragments.The impact effects of these threats on concrete and steel structures in a nuclear power plant are discussed.Methods and procedures for the impact assessment of nuclear power plants are introduced.Recent studies on penetration and perforation mechanics as well as progresses on dynamic properties of concrete-like materials are presented to increase the understanding of the impact effects on concrete containment structures.

  19. 76 FR 73600 - Taking and Importing Marine Mammals; Taking Marine Mammals Incidental to Missile Launch...

    Science.gov (United States)

    2011-11-29

    ... years if NMFS finds, after notification and opportunity for public comment, that the taking will have a... taking. Regulations governing the taking of northern elephant seals (Mirounga angustirostris), Pacific... a period not to exceed 1 year, take of pinnipeds, by harassment, incidental to missile launch...

  20. Research of Short-range Missile Motion in Terms of Different Wind Loads

    Directory of Open Access Journals (Sweden)

    A. N. Klishin

    2015-01-01

    Full Text Available When modeling the aircraft motion it is advisable to choose a particular model of the Earth, depending both on the task and on the required accuracy of calculation. The article describes various models of the Earth, such as the flat Earth with a plane-parallel field of gravity, spherical and non-rotating Earth with a plane-parallel field of gravity, spherical and non-rotating Earth with a central gravitational field, spherical and non-rotating Earth, taking into account the polar flattening of the Earth, spherical Earth based compression and polar daily rotation. The article also considers the influence of these models on the motion of the selected aircraft.To date, there is technical equipment to provide highly accurate description of the Earthshape, gravitational field, etc. The improved accuracy of the Earth model description results in more correct description of the trajectory and motion parameters of a ballistic missile. However, for short ranges (10-20 km this accuracy is not essential, and, furthermore, it increases time of calculation. Therefore, there is a problem of choosing the optimal description of the Earth parameters.The motion in the model of the Earth, which takes into account a daily rotation of the planet and polar flattening, is discussed in more detail, and the geographical latitude impact on coordinates of the points of fall of a ballistic missile is analyzed on the basis of obtained graphs.The article individually considers a problem of the wind effect on the aircraft motion and defines dependences of the missile motion on the parameters of different wind loads, such as wind speed and height of its action.A mathematical model of the missile motion was built and numerically integrated, using the Runge-Kutta 4th order method, for implementation and subsequent analysis.Based on the analysis of the calculation results in the abovementioned models of the Earth, differences in impact of these models on the parameters of the

  1. Safety catching device for pipes in missile shielding cylinders of nuclear power plants

    International Nuclear Information System (INIS)

    Hering, S.; Doll, B.

    1976-01-01

    The safety catching device consists of a steel wire passed in U-shape around the pipe to be caught and supported by two anchor ties embedded in the concrete of the missile shielding cylinder. This flexible catching device is to cause the energy released in case of a pipe rupture to be absorbed and no dangerous bending shesses to be transferred to the walls of the missile shielding cylinder. (UWI) [de

  2. Habitat or matrix: which is more relevant to predict road-kill of vertebrates?

    Science.gov (United States)

    Bueno, C; Sousa, C O M; Freitas, S R

    2015-11-01

    We believe that in tropics we need a community approach to evaluate road impacts on wildlife, and thus, suggest mitigation measures for groups of species instead a focal-species approach. Understanding which landscape characteristics indicate road-kill events may also provide models that can be applied in other regions. We intend to evaluate if habitat or matrix is more relevant to predict road-kill events for a group of species. Our hypothesis is: more permeable matrix is the most relevant factor to explain road-kill events. To test this hypothesis, we chose vertebrates as the studied assemblage and a highway crossing in an Atlantic Forest region in southeastern Brazil as the study site. Logistic regression models were designed using presence/absence of road-kill events as dependent variables and landscape characteristics as independent variables, which were selected by Akaike's Information Criterion. We considered a set of candidate models containing four types of simple regression models: Habitat effect model; Matrix types effect models; Highway effect model; and, Reference models (intercept and buffer distance). Almost three hundred road-kills and 70 species were recorded. River proximity and herbaceous vegetation cover, both matrix effect models, were associated to most road-killed vertebrate groups. Matrix was more relevant than habitat to predict road-kill of vertebrates. The association between river proximity and road-kill indicates that rivers may be a preferential route for most species. We discuss multi-species mitigation measures and implications to movement ecology and conservation strategies.

  3. 76 FR 46298 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-08-02

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: to provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held virtually on August 17, 2011...

  4. 76 FR 50734 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-08-16

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: to provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held on September 28, 2011, from 9...

  5. 77 FR 2727 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-01-19

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: To provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held on February 29, 2012, from 9...

  6. 76 FR 70455 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-11-14

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: to provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held on December 14, 2011, from 9...

  7. 75 FR 5595 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2010-02-03

    ... Technology HIT Standards Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National... Health Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT... Federal Health IT Strategic Plan, and in accordance with policies developed by the HIT Policy Committee...

  8. 77 FR 73661 - HIT Standards Committee Advisory Meetings; Notice of Meetings

    Science.gov (United States)

    2012-12-11

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meetings; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: To provide... developed by the HIT Policy Committee. Date and Time: These meetings will be held on the following dates and...

  9. 76 FR 70454 - HIT Policy Committee's Workgroup Meetings; Notice of Meetings

    Science.gov (United States)

    2011-11-14

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee's Workgroup Meetings; Notice of... be open to the public via dial-in access only. Name of Committees: HIT Policy Committee's Workgroups... certification criteria are needed. Date and Time: The HIT Policy Committee Workgroups will hold the following...

  10. 76 FR 28784 - HIT Standards Committee's Workgroup Meetings; Notice of Meetings

    Science.gov (United States)

    2011-05-18

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee's Workgroup Meetings; Notice of... be open to the public via dial-in access only. Name of Committees: HIT Standards Committee's... implementation of the Federal Health IT Strategic Plan, and in accordance with policies developed by the HIT...

  11. 76 FR 50736 - HIT Standards Committee's Workgroup Meetings; Notice of Meetings

    Science.gov (United States)

    2011-08-16

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee's Workgroup Meetings; Notice of... be open to the public via dial-in access only. Name of Committees: HIT Standards Committee's... implementation of the Federal Health IT Strategic Plan, and in accordance with policies developed by the HIT...

  12. 76 FR 14975 - HIT Standards Committee's Workgroup Meetings; Notice of Meetings

    Science.gov (United States)

    2011-03-18

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee's Workgroup Meetings; Notice of... be open to the public via dial-in access only. Name of Committees: HIT Standards Committee's... implementation of the Federal Health IT Strategic Plan, and in accordance with policies developed by the HIT...

  13. 77 FR 65691 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-10-30

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: To provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held on November 13, 2012, from 9...

  14. 77 FR 50690 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-08-22

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: To provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held on September 19, 2012, from 9...

  15. 75 FR 21628 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2010-04-26

    ... Technology HIT Standards Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Standards... Strategic Plan, and in accordance with policies developed by the HIT Policy Committee. Date and Time: The...

  16. 76 FR 55913 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-09-09

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: to provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held virtually on October 21, 2011...

  17. 77 FR 65690 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-10-30

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: To provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held on December 19, 2012, from 9...

  18. Are the rules for the right to self-defense outdated to address current conflicts like attacks from non-state actors and cyber-attacks?

    Directory of Open Access Journals (Sweden)

    Gonzalo J. Arias

    2017-06-01

    Full Text Available The latest US-led coalition’s attacks against ISIS in Syria raised the question whether states can use defensive force against non-state actors. Two critical incidents had previously triggered the discussion on the importance and consequences of cyber-attacks as a new form armed attacks. The first one occurred in Estonia in 2007, when the country experienced extensive computer hacking attacks that lasted several weeks. The second incident happened in 2008, during the Georgia–Russia conflict over South Ossetia, when Georgia experienced cyber-attacks similar to those suffered by Estonia in the previous year. Furthermore, on June 21, 2016, the central banks of Indonesia and South Korea were hit by cyber-attacks on their public websites since activist hacking group Anonymous pledged last month to target banks across the world. The previous incidents have created, once again, public questioning if the rules on the use of force and the right of self-defense established in the United Nations Charter are sufficient and efficient to address these new forms of attacks.

  19. Study on the perforation of reinforced concrete slabs by rigid missiles. General introduction

    International Nuclear Information System (INIS)

    Gueraud, R.; Sokolovsky, A.

    1975-01-01

    Problems encountered in computing nuclear plant protective devices against the impact of a given rigid missile (e.g. turbine disc fragments) are emphasized. The experimental program of balistic tests (missile velocities between 90m.s -1 and 170m.s -2 ) and reduced scale tests carried out in France is briefly outlined [fr

  20. "Guns do not kill, people do!"

    DEFF Research Database (Denmark)

    Lemche, Niels Peter

    2011-01-01

    The Bible does not kill, but many people who have read the Bible (in their way) have killed, virtually or in real.......The Bible does not kill, but many people who have read the Bible (in their way) have killed, virtually or in real....