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Sample records for hints olle hints

  1. Enhancing the Automatic Generation of Hints with Expert Seeding

    Science.gov (United States)

    Stamper, John; Barnes, Tiffany; Croy, Marvin

    2011-01-01

    The Hint Factory is an implementation of our novel method to automatically generate hints using past student data for a logic tutor. One disadvantage of the Hint Factory is the time needed to gather enough data on new problems in order to provide hints. In this paper we describe the use of expert sample solutions to "seed" the hint generation…

  2. Increased anxiety-related behaviour in Hint1 knockout mice.

    Science.gov (United States)

    Varadarajulu, Jeeva; Lebar, Maria; Krishnamoorthy, Gurumoorthy; Habelt, Sonja; Lu, Jia; Bernard Weinstein, I; Li, Haiyang; Holsboer, Florian; Turck, Christoph W; Touma, Chadi

    2011-07-07

    Several reports have implicated a role for the histidine triad nucleotide-binding protein-1 (Hint1) in psychiatric disorders. We have studied the emotional behaviour of male Hint1 knockout (Hint1 KO) mice in a battery of tests and performed biochemical analyses on brain tissue. The behavioural analysis revealed that Hint1 KO mice exhibit an increased emotionality phenotype compared to wildtype (WT) mice, while no significant differences in locomotion or general exploratory activity were noted. In the elevated plus-maze (EPM) test, the Hint1 KO animals entered the open arms of the apparatus less often than WT littermates. Similarly, in the dark-light box test, Hint1 KO mice spent less time in the lit compartment and the number of entries were reduced, which further confirmed an increased anxiety-related behaviour. Moreover, the Hint1 KO animals showed significantly more struggling and less floating behaviour in the forced swim test (FST), indicating an increased emotional arousal in aversive situations. Hint1 is known as a protein kinase C (PKC) interacting protein. Western blot analysis showed that PKCγ expression was elevated in Hint1 KO compared to WT mice. Interestingly, PKCγ mRNA levels of the two groups did not show a significant difference, implying a post-transcriptional PKCγ regulation. In addition, PKC enzymatic activity was increased in Hint1 KO compared to WT mice. In summary, our results indicate a role for Hint1 and PKCγ in modulating anxiety-related and stress-coping behaviour in mice. Copyright © 2011 Elsevier B.V. All rights reserved.

  3. Financial model calibration using consistency hints.

    Science.gov (United States)

    Abu-Mostafa, Y S

    2001-01-01

    We introduce a technique for forcing the calibration of a financial model to produce valid parameters. The technique is based on learning from hints. It converts simple curve fitting into genuine calibration, where broad conclusions can be inferred from parameter values. The technique augments the error function of curve fitting with consistency hint error functions based on the Kullback-Leibler distance. We introduce an efficient EM-type optimization algorithm tailored to this technique. We also introduce other consistency hints, and balance their weights using canonical errors. We calibrate the correlated multifactor Vasicek model of interest rates, and apply it successfully to Japanese Yen swaps market and US dollar yield market.

  4. Active Learning Using Hint Information.

    Science.gov (United States)

    Li, Chun-Liang; Ferng, Chun-Sung; Lin, Hsuan-Tien

    2015-08-01

    The abundance of real-world data and limited labeling budget calls for active learning, an important learning paradigm for reducing human labeling efforts. Many recently developed active learning algorithms consider both uncertainty and representativeness when making querying decisions. However, exploiting representativeness with uncertainty concurrently usually requires tackling sophisticated and challenging learning tasks, such as clustering. In this letter, we propose a new active learning framework, called hinted sampling, which takes both uncertainty and representativeness into account in a simpler way. We design a novel active learning algorithm within the hinted sampling framework with an extended support vector machine. Experimental results validate that the novel active learning algorithm can result in a better and more stable performance than that achieved by state-of-the-art algorithms. We also show that the hinted sampling framework allows improving another active learning algorithm designed from the transductive support vector machine.

  5. Hants Hint - kõigi ihaldatud kaalukeel / Hants Hint ; interv. Erik Gamzejev

    Index Scriptorium Estoniae

    Hint, Hants

    2002-01-01

    Ilmunud ka: Severnoje Poberezhje : Laupäev 26. okt. lk. 3. Res Publica Ida-Viru piirkonna juht Hants Hint: me oleme põhimõtteliselt valmis kõigi poliitiliste jõududega koostööd tegema. Autor: Res Publica

  6. Eating Hints: Before, During, and After Cancer Treatment

    Science.gov (United States)

    ... Publications Reports Eating Hints: Before, during, and after Cancer Treatment Eating Hints is for people who are having or are about to have cancer treatment. Family and friends may also want to read ...

  7. Astrophysical hints of axion-like particles

    Science.gov (United States)

    Roncadelli, M.; Galanti, G.; Tavecchio, F.; Bonnoli, G.

    2015-01-01

    After reviewing three astrophysical hints of the existence of axion-like particles (ALPs), we describe in more detail a new similar hint involving flat spectrum radio quasars (FSRQs). Detection of FSRQs above about 20GeV pose a challenge to very-high-energy (VHE) astrophysics, because at those energies the ultraviolet emission from their broad line region should prevent photons produced by the central engine to leave the source. Although a few astrophysical explanations have been put forward, they are totally ad hoc. We show that a natural explanation instead arises within the conventional models of FSRQs provided that photon-ALP oscillations occur inside the source. Our analysis takes the FSRQ PKR 1222+206 as an example, and it looks tantalizing that basically the same choice of the free model parameters adopted in this case is consistent with those that provide the other three hints of the existence of ALPs.

  8. HINTS Puerto Rico: Final Report

    Science.gov (United States)

    This final report describes HINTS implementation in Puerto Rico. The report addresses sampling; staffing, training and management of data collection; calling protocol; findings from the CATI Operations, and sample weights.

  9. An analytical model of the HINT performance metric

    Energy Technology Data Exchange (ETDEWEB)

    Snell, Q.O.; Gustafson, J.L. [Scalable Computing Lab., Ames, IA (United States)

    1996-10-01

    The HINT benchmark was developed to provide a broad-spectrum metric for computers and to measure performance over the full range of memory sizes and time scales. We have extended our understanding of why HINT performance curves look the way they do and can now predict the curves using an analytical model based on simple hardware specifications as input parameters. Conversely, by fitting the experimental curves with the analytical model, hardware specifications such as memory performance can be inferred to provide insight into the nature of a given computer system.

  10. HinT proteins and their putative interaction partners in Mollicutes and Chlamydiaceae

    Directory of Open Access Journals (Sweden)

    Hegemann Johannes H

    2005-05-01

    Full Text Available Background HinT proteins are found in prokaryotes and eukaryotes and belong to the superfamily of HIT proteins, which are characterized by an histidine-triad sequence motif. While the eukaryotic variants hydrolyze AMP derivates and modulate transcription, the function of prokaryotic HinT proteins is less clearly defined. In Mycoplasma hominis, HinT is concomitantly expressed with the proteins P60 and P80, two domains of a surface exposed membrane complex, and in addition interacts with the P80 moiety. Results An cluster of hitABL genes, similar to that of M. hominis was found in M. pulmonis, M. mycoides subspecies mycoides SC, M. mobile and Mesoplasma florum. RT-PCR analyses provided evidence that the P80, P60 and HinT homologues of M. pulmonis were polycistronically organized, suggesting a genetic and physical interaction between the proteins encoded by these genes in these species. While the hit loci of M. pneumoniae and M. genitalium encoded, in addition to HinT, a protein with several transmembrane segments, the hit locus of Ureaplasma parvum encoded a pore-forming protein, UU270, a P60 homologue, UU271, HinT, UU272, and a membrane protein of unknown function, UU273. Although a full-length mRNA spanning the four genes was not detected, amplification of all intergenic regions from the center of UU270 to the end of UU273 by RT-PCR may be indicative of a common, but unstable mRNA. In Chlamydiaceae the hit gene is flanked upstream by a gene predicted to encode a metal dependent hydrolase and downstream by a gene putatively encoding a protein with ARM-repeats, which are known to be involved in protein-protein interactions. In RT-PCR analyses of C. pneumoniae, regions comprising only two genes, Cp265/Cp266 and Cp266/Cp267 were able to be amplified. In contrast to this in vivo interaction analysis using the yeast two-hybrid system and in vitro immune co-precipitation revealed an interaction between Cp267, which contains the ARM repeats, Cp265, the

  11. Understanding Attention to Adaptive Hints in Educational Games: An Eye-Tracking Study

    Science.gov (United States)

    Conati, Cristina; Jaques, Natasha; Muir, Mary

    2013-01-01

    This paper presents a user study that investigates the factors affecting student attention to user-adaptive hints during interaction with an educational computer game. The study focuses on Prime Climb, an educational game designed to provide individualized support for learning number factorization skills in the form of textual hints based on a…

  12. Hint2, the mitochondrial nucleoside 5'-phosphoramidate hydrolase; properties of the homogeneous protein from sheep (Ovis aries) liver.

    Science.gov (United States)

    Bretes, Ewa; Wojdyła-Mamoń, Anna M; Kowalska, Joanna; Jemielity, Jacek; Kaczmarek, Renata; Baraniak, Janina; Guranowski, Andrzej

    2013-01-01

    Adenosine 5'-phosphoramidate (NH2-pA) is a rare natural nucleotide and its biochemistry and biological functions are poorly recognized. All organisms have proteins that may be involved in the catabolism of NH2-pA. They are members of the HIT protein family and catalyze hydrolytic splitting of NH2-pA to 5'-AMP and ammonia. At least five HIT proteins have been identified in mammals; however, the enzymatic and molecular properties of only Fhit and Hint1 have been comprehensively studied. Our study focuses on the Hint2 protein purified by a simple procedure to homogeneity from sheep liver mitochondrial fraction (OaHint2). Hint1 protein was also prepared from sheep liver (OaHint1) and the molecular and kinetic properties of the two proteins compared. Both function as homodimers and behave as nucleoside 5'-phosphoramidate hydrolases. The molecular mass of the OaHint2 monomer is 16 kDa and that of the OaHint1 monomer 14.9 kDa. Among potential substrates studied, NH2-pA appeared to be the best; the Km and kcat values estimated for this compound are 6.6 μM and 68.3 s⁻¹, and 1.5 μM and 11.0 s⁻¹ per natively functioning dimer of OaHint2 and OaHint1, respectively. Studies of the rates of hydrolysis of different NH2-pA derivatives show that Hint2 is more specific towards compounds with a P-N bond than Hint1. The thermostability of these two proteins is also compared.

  13. Observational Hints of a Pre--Inflationary Scale?

    CERN Document Server

    Gruppuso, A.

    2015-09-28

    We argue that the lack of power exhibited by cosmic microwave background (CMB) anisotropies at large angular scales might be linked to the onset of inflation. We highlight observational features and theoretical hints that support this view, and present a preliminary estimate of the physical scale that would underlie the phenomenon.

  14. A two-Higgs-doublet model facing experimental hints

    Directory of Open Access Journals (Sweden)

    Crivellin Andreas

    2016-01-01

    Full Text Available Physics beyond the Standard Model has so far eluded our experimental probes. Nevertheless, a number of interesting anomalies have accumulated that can be taken as hints towards new physics: BaBar, Belle, and LHCb have found deviations of approximately 3:8σ in B → Dτν and B → D*τν; the anomalous magnetic moment of the muon differs by about 3σ from the theoretic prediction; the branching ratio for τ → μνν is about 2σ above the Standard Model expectation; and CMS and ATLAS found hints for a non-zero decay rate of h → μτ at 2.6σ. Here we consider these processes within a lepton-specific two-Higgs doublet model with additional non-standard Yukawa couplings and show how (and which of these excesses can be accommodated.

  15. Gaze-based hints during child-robot gameplay

    NARCIS (Netherlands)

    Mwangi, E.; Barakova, Emilia I.; Diaz, M.L.Z.; Mallofre, A.C.; Rauterberg, G.W.M.; Kheddar, A.; Yoshida, E.; Sam Ge, S.; Suzuki, K.; Cabibihan, J.J.; Eyssel, F.; He, H.

    2017-01-01

    This paper presents a study that examines whether gaze hints provided by a robot tutor influences the behavior of children in a card matching game. In this regard, we conducted a within-subjects experiment, in which children played a card game “Memory” in the presence of a robot tutor in two

  16. Anti-depressant and anxiolytic like behaviors in PKCI/HINT1 knockout mice associated with elevated plasma corticosterone level

    Directory of Open Access Journals (Sweden)

    Wang Jia

    2009-11-01

    Full Text Available Abstract Background Protein kinase C interacting protein (PKCI/HINT1 is a small protein belonging to the histidine triad (HIT family proteins. Its brain immunoreactivity is located in neurons and neuronal processes. PKCI/HINT1 gene knockout (KO mice display hyper-locomotion in response to D-amphetamine which is considered a positive symptom of schizophrenia in animal models. Postmortem studies identified PKCI/HINT1 as a candidate molecule for schizophrenia and bipolar disorder. We investigated the hypothesis that the PKCI/HINT1 gene may play an important role in regulating mood function in the CNS. We submitted PKCI/HINT1 KO mice and their wild type (WT littermates to behavioral tests used to study anti-depressant, anxiety like behaviors, and goal-oriented behavior. Additionally, as many mood disorders coincide with modifications of hypothalamic-pituitary-adrenal (HPA axis function, we assessed the HPA activity through measurement of plasma corticosterone levels. Results Compared to the WT controls, KO mice exhibited less immobility in the forced swim (FST and the tail suspension (TST tests. Activity in the TST tended to be attenuated by acute treatment with valproate at 300 mg/kg in KO mice. The PKCI/HINT1 KO mice presented less thigmotaxis in the Morris water maze and spent progressively more time in the lit compartment in the light/dark test. In a place navigation task, KO mice exhibited enhanced acquisition and retention. Furthermore, the afternoon basal plasma corticosterone level in PKCI/HINT1 KO mice was significantly higher than in the WT. Conclusion PKCI/HINT1 KO mice displayed a phenotype of behavioral and endocrine features which indicate changes of mood function, including anxiolytic-like and anti-depressant like behaviors, in conjunction with an elevated corticosterone level in plasma. These results suggest that the PKCI/HINT 1 gene could be important for the mood regulation function in the CNS.

  17. Theory of mind in a first-episode psychosis population using the Hinting Task.

    Science.gov (United States)

    Lindgren, Maija; Torniainen-Holm, Minna; Heiskanen, Inkeri; Voutilainen, Greta; Pulkkinen, Ulla; Mehtälä, Tuukka; Jokela, Markus; Kieseppä, Tuula; Suvisaari, Jaana; Therman, Sebastian

    2018-05-01

    Deficiencies in theory of mind (ToM) are common in psychosis and may largely explain impaired social functioning. Currently, it is unclear whether impairments in ToM are explained by the more general cognitive deficits related to psychosis or whether ToM is impaired in psychosis independently of other cognitive deficits. This study examined ToM using the Hinting Task in young adults (n = 66) with first-episode psychosis and matched controls (n = 62). The participants were administered a broad neuropsychological assessment. Participants with psychosis performed worse than controls on the Hinting Task. However, 75% of the variance between the groups was explained by general cognitive deficits, especially impaired processing speed and episodic memory. Hinting Task performance of the best functioning patient group did not differ from that of the control group. When the psychosis group was divided according to diagnosis, the Hinting Task difference between individuals with schizophrenia and controls remained significant even when general cognitive performance was controlled for, suggesting specific verbal ToM deficits in schizophrenia. In contrast, those with other psychotic disorders did not differ from controls. Our results suggest that ToM deficits can be seen in early phases of psychotic disorders, schizophrenia in particular, and are partly independent of other cognitive functions. Copyright © 2018 Elsevier B.V. All rights reserved.

  18. Pigeons (Columba livia) know when they will need hints: prospective metacognition for reference memory?

    Science.gov (United States)

    Iwasaki, Sumie; Watanabe, Sota; Fujita, Kazuo

    2018-03-01

    Despite their impressive cognitive abilities, avian species have shown less evidence for metacognition than mammals. We suspect that commonly used tasks such as matching to sample might be too demanding to allow metacognitive processing within birds' working memory. Here, we examined whether pigeons could control their behavior as a function of knowledge levels on a three-item sequence learning task, a reference memory task supposedly requiring fewer working memory resources. The experiment used two types of lists differing in familiarity. One was familiar to the pigeons through repeated exposure, whereas the other was novel in every new session. In test sessions, pigeons could choose between a trial with a hint specifying the next item to peck and one with no hint. However, successful responses in trials with a hint resulted in lowered rates of primary reinforcement: .60 in the first test and .75 in the second. Results showed that two of four pigeons chose the trial with a hint significantly more often before receiving a novel list than the familiar list in the four sessions of the first test, and three did so in the second test. Impressively, one bird showed robust evidence in the very first sessions in both tests. These results suggest that pigeons may monitor their long-term knowledge states and thereby control their environment before starting to solve a task.

  19. HINTS outperforms ABCD2 to screen for stroke in acute continuous vertigo and dizziness.

    Science.gov (United States)

    Newman-Toker, David E; Kerber, Kevin A; Hsieh, Yu-Hsiang; Pula, John H; Omron, Rodney; Saber Tehrani, Ali S; Mantokoudis, Georgios; Hanley, Daniel F; Zee, David S; Kattah, Jorge C

    2013-10-01

    Dizziness and vertigo account for about 4 million emergency department (ED) visits annually in the United States, and some 160,000 to 240,000 (4% to 6%) have cerebrovascular causes. Stroke diagnosis in ED patients with vertigo/dizziness is challenging because the majority have no obvious focal neurologic signs at initial presentation. The authors sought to compare the accuracy of two previously published approaches purported to be useful in bedside screening for possible stroke in dizziness: a clinical decision rule (head impulse, nystagmus type, test of skew [HINTS]) and a risk stratification rule (age, blood pressure, clinical features, duration of symptoms, diabetes [ABCD2]). This was a cross-sectional study of high-risk patients (more than one stroke risk factor) with acute vestibular syndrome (AVS; acute, persistent vertigo or dizziness with nystagmus, plus nausea or vomiting, head motion intolerance, and new gait unsteadiness) at a single academic center. All underwent neurootologic examination, neuroimaging (97.4% by magnetic resonance imaging [MRI]), and follow-up. ABCD2 risk scores (0-7 points), using the recommended cutoff of ≥4 for stroke, were compared to a three-component eye movement battery (HINTS). Sensitivity, specificity, and positive and negative likelihood ratios (LR+, LR-) were assessed for stroke and other central causes, and the results were stratified by age. False-negative initial neuroimaging was also assessed. A total of 190 adult AVS patients were assessed (1999-2012). Median age was 60.5 years (range = 18 to 92 years; interquartile range [IQR] = 52.0 to 70.0 years); 60.5% were men. Final diagnoses were vestibular neuritis (34.7%), posterior fossa stroke (59.5% [105 infarctions, eight hemorrhages]), and other central causes (5.8%). Median ABCD2 was 4.0 (range = 2 to 7; IQR = 3.0 to 4.0). ABCD2 ≥ 4 for stroke had sensitivity of 61.1%, specificity of 62.3%, LR+ of 1.62, and LR- of 0.62; sensitivity was lower for those

  20. Stoic Behavior Hypothesis in Hint Seeking and Development of Reversi Learning Environment as Work Bench for Investigation

    Science.gov (United States)

    Miwa, Kazuhisa; Kojima, Kazuaki; Terai, Hitoshi

    2014-01-01

    Tutoring systems provide students with various types of on-demand and context-sensitive hints. Students are required to consciously adapt their help-seeking behavior, proactively seek help in some situations, and solve problems independently without supports in other situations. We define the latter behavior as stoic behavior in hint seeking. In…

  1. Res Publicas käärib mäss / Hants Hint

    Index Scriptorium Estoniae

    Hint, Hants

    2002-01-01

    Res Publica eestseisuse liige ja Ida-Viru piirkonna esimees Hants Hint vastab küsimustele Res Publica ja Keskerakonna võimuliidu moodustamisega tekkinud skandaali, Res Publica esimehe Juhan Partsiga kohtumise kohta. Vt. samas: "Korbi toetajaid ootab hukkamõist"

  2. New physics hints in B decays and collider outlook

    Indian Academy of Sciences (India)

    There are currently two hints for new physics involving CP violation in → transitions: ≡ - / ≠ 0, and difference in direct CP asymmetry Δ A K π ≡ A K + π 0 − A K + π ≠ 0 . We explore the two scenarious with a large and unique new CP phase in ← tansitions. Motivated by ≠ 0, we update on the ...

  3. [Peripheral vertigo versus central vertigo. Application of the HINTS protocol].

    Science.gov (United States)

    Batuecas-Caletrío, Ángel; Yáñez-González, Raquel; Sánchez-Blanco, Carmen; González-Sánchez, Enrique; Benito, José; Gómez, José Carlos; Santa Cruz-Ruiz, Santiago

    2014-10-16

    One of the most important dilemmas concerning vertigo in emergency departments is its differential diagnosis. There are highly sensitive warning signs in the examination that can put us on the path towards finding ourselves before a case of central vertigo. To determine how effective the application of the HINTS protocol is in the diagnosis of cerebrovascular accidents that mimics peripheral vertigo. We conducted a descriptive observation-based study on patients admitted to hospital with a diagnosis of acute vestibular syndrome in the emergency department. All the patients were monitored on a day-to-day basis until their symptoms improved, with information about nystagmus, the oculocephalic manoeuvre and the skew test. The results from the magnetic resonance imaging study were compared with the alteration of any of those three signs during the time the patient was hospitalised. Altogether 91 patients were examined, with a mean age of 55.8 years. A cerebrovascular accident was observed in eight cases. Of these (mean age: 71 years), in seven of them there were alterations in some of the HINTS signs, and in one case the study was normal (sensitivity: 0.88; specificity: 0.96). All of them had some vascular risk factor. Faced with a patient who visits the emergency department with an acute vestibular syndrome, a suitably directed examination is essential to be able to establish the differential diagnosis between peripheral and central pathology, since some cerebrovascular accidents can present with the appearance of acute vertigo. Applying a protocol like HINTS makes it possible to suspect the central pathology with a high degree of sensitivity and specificity.

  4. Experimental hint for gravitational CP violation

    Energy Technology Data Exchange (ETDEWEB)

    Gharibyan, Vahagn [Deutsches Elektronen-Synchrotron, Hamburg (Germany). MDI Group

    2016-01-15

    An equality of particle and antiparticle gravitational interactions holds in general relativity and is supported by indirect observations. Gravity dependence on rotation or spin direction is experimentally constrained only at low energies. Here a method based on high energy Compton scattering is developed to measure the gravitational interaction of accelerated charged particles. Within that formalism the Compton spectra measured at HERA rule out the positron's anti-gravity and hint for a gravitational CP violation around 13 GeV energies, at a maximal level of 1.3±0.2% for the charge and 0.68±0.09% for the space parity. A stronger gravitational coupling to left helicity electrons relative to right helicity positrons is detected.

  5. Experimental hint for gravitational CP violation

    International Nuclear Information System (INIS)

    Gharibyan, Vahagn

    2016-01-01

    An equality of particle and antiparticle gravitational interactions holds in general relativity and is supported by indirect observations. Gravity dependence on rotation or spin direction is experimentally constrained only at low energies. Here a method based on high energy Compton scattering is developed to measure the gravitational interaction of accelerated charged particles. Within that formalism the Compton spectra measured at HERA rule out the positron's anti-gravity and hint for a gravitational CP violation around 13 GeV energies, at a maximal level of 1.3±0.2% for the charge and 0.68±0.09% for the space parity. A stronger gravitational coupling to left helicity electrons relative to right helicity positrons is detected.

  6. Employing UMLS for generating hints in a tutoring system for medical problem-based learning.

    Science.gov (United States)

    Kazi, Hameedullah; Haddawy, Peter; Suebnukarn, Siriwan

    2012-06-01

    While problem-based learning has become widely popular for imparting clinical reasoning skills, the dynamics of medical PBL require close attention to a small group of students, placing a burden on medical faculty, whose time is over taxed. Intelligent tutoring systems (ITSs) offer an attractive means to increase the amount of facilitated PBL training the students receive. But typical intelligent tutoring system architectures make use of a domain model that provides a limited set of approved solutions to problems presented to students. Student solutions that do not match the approved ones, but are otherwise partially correct, receive little acknowledgement as feedback, stifling broader reasoning. Allowing students to creatively explore the space of possible solutions is exactly one of the attractive features of PBL. This paper provides an alternative to the traditional ITS architecture by using a hint generation strategy that leverages a domain ontology to provide effective feedback. The concept hierarchy and co-occurrence between concepts in the domain ontology are drawn upon to ascertain partial correctness of a solution and guide student reasoning towards a correct solution. We describe the strategy incorporated in METEOR, a tutoring system for medical PBL, wherein the widely available UMLS is deployed and represented as the domain ontology. Evaluation of expert agreement with system generated hints on a 5-point likert scale resulted in an average score of 4.44 (Spearman's ρ=0.80, p<0.01). Hints containing partial correctness feedback scored significantly higher than those without it (Mann Whitney, p<0.001). Hints produced by a human expert received an average score of 4.2 (Spearman's ρ=0.80, p<0.01). Copyright © 2012 Elsevier Inc. All rights reserved.

  7. Complexity hints for economic policy

    CERN Document Server

    Salzano, Massimo

    2007-01-01

    This volume extends the complexity approach to economics. This complexity approach is not a completely new way of doing economics, and that it is a replacement for existing economics, but rather the integration of some new analytic and computational techniques into economists’ bag of tools. It provides some alternative pattern generators, which can supplement existing approaches by providing an alternative way of finding patterns than be obtained by the traditional scientific approach. On this new kind of policy hints can be obtained. The reason why the complexity approach is taking hold now in economics is because the computing technology has advanced. This advance allows consideration of analytical systems that could not previously be considered by economists. Consideration of these systems suggested that the results of the "control-based" models might not extend easily to more complicated systems, and that we now have a method—piggybacking computer assisted analysis onto analytic methods—to start gen...

  8. The Diagnostic Accuracy of Truncal Ataxia and HINTS as Cardinal Signs for Acute Vestibular Syndrome

    Directory of Open Access Journals (Sweden)

    Sergio Carmona

    2016-08-01

    Full Text Available The head impulse, nystagmus type, test of skew (HINTS protocol set a new paradigm to differentiate peripheral vestibular disease from stroke in patients with acute vestibular syndrome (AVS. The relationship between degree of truncal ataxia and stroke has not been systematically studied in patients with AVS. We studied a group of 114 patients who were admitted to a General Hospital due to AVS, 72 of them with vestibular neuritis (based on positive head impulse, abnormal caloric tests and negative MRI, and the rest with Stroke: 32 in the PICA territory (positive HINTS findings, positive MRI and 10 in the AICA territory (variable findings and grade 3 Ataxia, positive MRI. Truncal ataxia was measured by independent observers as grade 1, mild to moderate imbalance with walking independently; grade 2, severe imbalance with standing, but cannot walk without support; and grade 3, falling at upright posture.When we applied the HINTS protocol to our sample, we obtained 100% sensitivity and 94.4% specificity, similar to previously published findings. Only those patients with stroke presented with grade 3 ataxia. Of those with grade 2 ataxia (n = 38, 11 had cerebellar stroke and 28 had vestibular neuritis, not related to the patient's age. Grade 2-3 ataxia was 92.9% sensitive and 61.1% specific to detect AICA/PICA stroke in patients with AVS, with 100% sensitivity to detect AICA stroke. In turn, two signs (nystagmus of central origin and grade 2-3 Ataxia had 100% sensitivity and 61.1% specificity. Ataxia is less sensitive than HINTS but much easier to evaluate.

  9. Can children take advantage of nao gaze-based hints during gameplay?

    NARCIS (Netherlands)

    Mwangi, E.N.; Diaz, M.; Barakova, E.I.; Catala, A.; Rauterberg, G.W.M.

    2017-01-01

    This paper presents a study that analyzes the effects of robots' gaze hints on children's performance in a card-matching game. We conducted a within-subjects study, in which children played a card matching game "Memory" in the presence of a robot tutor in two sessions. In one session, the robot gave

  10. HINT computation of LHD equilibrium with zero rotational transform surface

    International Nuclear Information System (INIS)

    Kanno, Ryutaro; Toi, Kazuo; Watanabe, Kiyomasa; Hayashi, Takaya; Miura, Hideaki; Nakajima, Noriyoshi; Okamoto Masao

    2004-01-01

    A Large Helical Device equilibrium having a zero rotational transform surface is studied by using the three dimensional MHD equilibrium code, HINT. We find existence of the equilibrium but with formation of the two or three n=0 islands composing a homoclinic-type structure near the center, where n is a toroidal mode number. The LHD equilibrium maintains the structure, when the equilibrium beta increases. (author)

  11. Health Information National Trends Survey in American Sign Language (HINTS-ASL): Protocol for the Cultural Adaptation and Linguistic Validation of a National Survey.

    Science.gov (United States)

    Kushalnagar, Poorna; Harris, Raychelle; Paludneviciene, Raylene; Hoglind, TraciAnn

    2017-09-13

    The Health Information National Trends Survey (HINTS) collects nationally representative data about the American's public use of health-related information. This survey is available in English and Spanish, but not in American Sign Language (ASL). Thus, the exclusion of ASL users from these national health information survey studies has led to a significant gap in knowledge of Internet usage for health information access in this underserved and understudied population. The objectives of this study are (1) to culturally adapt and linguistically translate the HINTS items to ASL (HINTS-ASL); and (2) to gather information about deaf people's health information seeking behaviors across technology-mediated platforms. We modified the standard procedures developed at the US National Center for Health Statistics Cognitive Survey Laboratory to culturally adapt and translate HINTS items to ASL. Cognitive interviews were conducted to assess clarity and delivery of these HINTS-ASL items. Final ASL video items were uploaded to a protected online survey website. The HINTS-ASL online survey has been administered to over 1350 deaf adults (ages 18 to 90 and up) who use ASL. Data collection is ongoing and includes deaf adult signers across the United States. Some items from HINTS item bank required cultural adaptation for use with deaf people who use accessible services or technology. A separate item bank for deaf-related experiences was created, reflecting deaf-specific technology such as sharing health-related ASL videos through social network sites and using video remote interpreting services in health settings. After data collection is complete, we will conduct a series of analyses on deaf people's health information seeking behaviors across technology-mediated platforms. HINTS-ASL is an accessible health information national trends survey, which includes a culturally appropriate set of items that are relevant to the experiences of deaf people who use ASL. The final HINTS

  12. Interaction Networks: Generating High Level Hints Based on Network Community Clustering

    Science.gov (United States)

    Eagle, Michael; Johnson, Matthew; Barnes, Tiffany

    2012-01-01

    We introduce a novel data structure, the Interaction Network, for representing interaction-data from open problem solving environment tutors. We show how using network community detecting techniques are used to identify sub-goals in problems in a logic tutor. We then use those community structures to generate high level hints between sub-goals.…

  13. PsHint1, associated with the G-protein α subunit PsGPA1, is required for the chemotaxis and pathogenicity of Phytophthora sojae.

    Science.gov (United States)

    Zhang, Xin; Zhai, Chunhua; Hua, Chenlei; Qiu, Min; Hao, Yujuan; Nie, Pingping; Ye, Wenwu; Wang, Yuanchao

    2016-02-01

    Zoospore chemotaxis to soybean isoflavones is essential in the early stages of infection by the oomycete pathogen Phytophthora sojae. Previously, we have identified a G-protein α subunit encoded by PsGPA1 which regulates the chemotaxis and pathogenicity of P. sojae. In the present study, we used affinity purification to identify PsGPA1-interacting proteins, including PsHint1, a histidine triad (HIT) domain-containing protein orthologous to human HIT nucleotide-binding protein 1 (HINT1). PsHint1 interacted with both the guanosine triphosphate (GTP)- and guanosine diphosphate (GDP)-bound forms of PsGPA1. An analysis of the gene-silenced transformants revealed that PsHint1 was involved in the chemotropic response of zoospores to the isoflavone daidzein. During interaction with a susceptible soybean cultivar, PsHint1-silenced transformants displayed significantly reduced infectious hyphal extension and caused a strong cell death in plants. In addition, the transformants displayed defective cyst germination, forming abnormal germ tubes that were highly branched and exhibited apical swelling. These results suggest that PsHint1 not only regulates chemotaxis by interacting with PsGPA1, but also participates in a Gα-independent pathway involved in the pathogenicity of P. sojae. © 2015 BSPP AND JOHN WILEY & SONS LTD.

  14. Pedagogical Agent Gestures to Improve Learner Comprehension of Abstract Concepts in Hints

    Science.gov (United States)

    Martins, Igor; de Morais, Felipe; Schaab, Bruno; Jaques, Patricia

    2016-01-01

    In most Intelligent Tutoring Systems, the help messages (hints) are not very clear for students as they are only presented textually and have little connection with the task elements. This can lead to students' undesired behaviors, like gaming the system, associated with low performance. In this paper, the authors aim at evaluating if the gestures…

  15. HINT-KB: The human interactome knowledge base

    KAUST Repository

    Theofilatos, Konstantinos A.

    2012-01-01

    Proteins and their interactions are considered to play a significant role in many cellular processes. The identification of Protein-Protein interactions (PPIs) in human is an open research area. Many Databases, which contain information about experimentally and computationally detected human PPIs as well as their corresponding annotation data, have been developed. However, these databases contain many false positive interactions, are partial and only a few of them incorporate data from various sources. To overcome these limitations, we have developed HINT-KB (http://150.140.142.24:84/Default.aspx) which is a knowledge base that integrates data from various sources, provides a user-friendly interface for their retrieval, estimates a set of features of interest and computes a confidence score for every candidate protein interaction using a modern computational hybrid methodology. © 2012 IFIP International Federation for Information Processing.

  16. Altered Light Conditions Contribute to Abnormalities in Emotion and Cognition Through HINT1 Dysfunction in C57BL/6 Mice

    Directory of Open Access Journals (Sweden)

    Yuan Zhou

    2018-06-01

    Full Text Available In recent years, the environmental impact of artificial light at night has been a rapidly growing global problem, affecting 99% of the population in the US and Europe, and 62% of the world population. The present study utilized a mouse model exposed to long-term artificial light and light deprivation to explore the impact of these conditions on emotion and cognition. Based on the potential links between histidine triad nucleotide binding protein 1 (HINT1 and mood disorders, we also examined the expression of HINT1 and related apoptosis factors in the suprachiasmatic nucleus (SCN, prefrontal cortex (PFC, nucleus accumbens (NAc and hippocampus (Hip. Mice exposed to constant light (CL exhibited depressive- and anxiety-like behaviors, as well as impaired spatial memory, as demonstrated by an increased immobility time in the tail suspension and forced swimming tests, less entries and time spent in the open arms of elevated plus-maze, and less platform site crossings and time spent in the target quadrant in the Morris water maze (MWM. The effects of constant darkness (CD partially coincided with long-term illumination, except that mice in the CD group failed to show anxiety-like behaviors. Furthermore, HINT1 was upregulated in four encephalic regions, indicating that HINT1 may be involved in mood disorders and cognitive impairments due to altered light exposure. The apoptosis-related proteins, BAX and BCL-2, showed the opposite expression pattern, reflecting an activated apoptotic pathway. These findings suggest that exposure to CL and/or darkness can induce significant changes in affective and cognitive responses, possibly through HINT1-induced activation of apoptotic pathways.

  17. Data-Driven Hint Generation in Vast Solution Spaces: A Self-Improving Python Programming Tutor

    Science.gov (United States)

    Rivers, Kelly; Koedinger, Kenneth R.

    2017-01-01

    To provide personalized help to students who are working on code-writing problems, we introduce a data-driven tutoring system, ITAP (Intelligent Teaching Assistant for Programming). ITAP uses state abstraction, path construction, and state reification to automatically generate personalized hints for students, even when given states that have not…

  18. Development and Validation of a Novel Generic Health-related Quality of Life Instrument With 20 Items (HINT-20

    Directory of Open Access Journals (Sweden)

    Min-Woo Jo

    2017-01-01

    Full Text Available Objectives Few attempts have been made to develop a generic health-related quality of life (HRQoL instrument and to examine its validity and reliability in Korea. We aimed to do this in our present study. Methods After a literature review of existing generic HRQoL instruments, a focus group discussion, in-depth interviews, and expert consultations, we selected 30 tentative items for a new HRQoL measure. These items were evaluated by assessing their ceiling effects, difficulty, and redundancy in the first survey. To validate the HRQoL instrument that was developed, known-groups validity and convergent/discriminant validity were evaluated and its test-retest reliability was examined in the second survey. Results Of the 30 items originally assessed for the HRQoL instrument, four were excluded due to high ceiling effects and six were removed due to redundancy. We ultimately developed a HRQoL instrument with a reduced number of 20 items, known as the Health-related Quality of Life Instrument with 20 items (HINT-20, incorporating physical, mental, social, and positive health dimensions. The results of the HINT-20 for known-groups validity were poorer in women, the elderly, and those with a low income. For convergent/discriminant validity, the correlation coefficients of items (except vitality in the physical health dimension with the physical component summary of the Short Form 36 version 2 (SF-36v2 were generally higher than the correlations of those items with the mental component summary of the SF-36v2, and vice versa. Regarding test-retest reliability, the intraclass correlation coefficient of the total HINT-20 score was 0.813 (p<0.001. Conclusions A novel generic HRQoL instrument, the HINT-20, was developed for the Korean general population and showed acceptable validity and reliability.

  19. The relationship between high-frequency pure-tone hearing loss, hearing in noise test (HINT) thresholds, and the articulation index.

    Science.gov (United States)

    Vermiglio, Andrew J; Soli, Sigfrid D; Freed, Daniel J; Fisher, Laurel M

    2012-01-01

    Speech recognition in noise testing has been conducted at least since the 1940s (Dickson et al, 1946). The ability to recognize speech in noise is a distinct function of the auditory system (Plomp, 1978). According to Kochkin (2002), difficulty recognizing speech in noise is the primary complaint of hearing aid users. However, speech recognition in noise testing has not found widespread use in the field of audiology (Mueller, 2003; Strom, 2003; Tannenbaum and Rosenfeld, 1996). The audiogram has been used as the "gold standard" for hearing ability. However, the audiogram is a poor indicator of speech recognition in noise ability. This study investigates the relationship between pure-tone thresholds, the articulation index, and the ability to recognize speech in quiet and in noise. Pure-tone thresholds were measured for audiometric frequencies 250-6000 Hz. Pure-tone threshold groups were created. These included a normal threshold group and slight, mild, severe, and profound high-frequency pure-tone threshold groups. Speech recognition thresholds in quiet and in noise were obtained using the Hearing in Noise Test (HINT) (Nilsson et al, 1994; Vermiglio, 2008). The articulation index was determined by using Pavlovic's method with pure-tone thresholds (Pavlovic, 1989, 1991). Two hundred seventy-eight participants were tested. All participants were native speakers of American English. Sixty-three of the original participants were removed in order to create groups of participants with normal low-frequency pure-tone thresholds and relatively symmetrical high-frequency pure-tone threshold groups. The final set of 215 participants had a mean age of 33 yr with a range of 17-59 yr. Pure-tone threshold data were collected using the Hughson-Weslake procedure. Speech recognition data were collected using a Windows-based HINT software system. Statistical analyses were conducted using descriptive, correlational, and multivariate analysis of covariance (MANCOVA) statistics. The

  20. Hint of a Z' boson from the CERN LEP II data

    International Nuclear Information System (INIS)

    Gulov, A. V.; Skalozub, V. V.

    2007-01-01

    The many-parametric fits of the LEP2 data on e + e - →e + e - , μ + μ - , τ + τ - processes are performed with the goal to estimate the signals of the Abelian Z ' boson. Four independent parameters must be fitted, if the derived already low-energy relations between the Z ' couplings to the standard model fermions are taken into consideration. No signals are found when the complete LEP2 data set for these processes is treated. In the fit of the backward bins, the hint at the 1.3σ confidence level is detected. The Z ' couplings to the vector and axial-vector lepton currents are constrained. The comparisons with the one-parameter fits and with the corresponding LEP1 experiments are fulfilled

  1. Axion-like particles: possible hints and constraints from the high-energy Universe

    International Nuclear Information System (INIS)

    Brun, Pierre

    2013-01-01

    The high-energy Universe is potentially a great laboratory for searching new light bosons such as axion-like particles (ALPs). Cosmic sources are indeed the scene of violent phenomena that involve strong magnetic field and/or very long baselines, where the effects of the mixing of photons with ALPs could lead to observable effects. Two examples are archetypal of this fact, that are the Universe opacity to gamma-rays and the imprints of astrophysical magnetic turbulence in the energy spectra of high-energy sources. In the first case, hints for the existence of ALPs can be proposed whereas the second one is used to put constraints on the ALP mass and coupling to photons

  2. Hints for clarification of influencing factors in case of occupational liver diseases

    Energy Technology Data Exchange (ETDEWEB)

    Zober, A; Raithel, H; Valentin, H

    1981-05-01

    Clarification of influencing factors is of great importance in suspected occupational liver diseases. Hints are given on the basis of the author's own experience and after critical evaluation of the relevant literature. Most important are: 1) Establishment of a comprehensive working anamnesis with special regard to specific features of the job, exposure patterns, and all working materials; 2) assessment of the hepatotoxic potential of the suspected working material according to the present state of knowledge in working medicine and toxicology; 3) objectification and quantification of the suspected noxious substances at the place of work by means of air analysis and analysis of the biological matter; 4) differential diagnosis in view of possible competitive influencing factors.

  3. New physics hints in Β decays and collider outlook

    International Nuclear Information System (INIS)

    Hou, George W.S.

    2006-01-01

    There are currently two hints for new physics involving CP violation in b →s transitions: ΔS ≡ S f - S J/ ψK ≠ 0, and difference in direct CP asymmetry ΔA Kπ ≡ A K + π 0 - A K + π - ≠0. We explore the two scenarios with a large and unique new CP phase in b s transitions. Motivated by ΔS ≠ 0, we update on the right-handed strange beauty squark sb 1R at TeV scale. Motivated by ΔA Kπ ≠ 0, we explore sequential fourth generation t and b quarks. Both scenarios can survive constraints such as SM level b→sγ, sll and Β s mixing, and predict sizable CP violation in Β s mixing. The fourth generation picture predicts sizable K L → π 0 νν. Direct search for sb R , b' and t' at hadronic colliders, such as Tevatron Run II and LHC, can complement further CP violation studies at these machines, as well as at the future Super Β factory. (author)

  4. Hint of nonstandard Mikheyev-Smirnov-Wolfenstein dynamics in solar neutrino conversion

    Science.gov (United States)

    Palazzo, Antonio

    2011-05-01

    Motivated by the recent low-threshold measurements of the solar B8 neutrino spectrum performed by Borexino, Super-Kamiokande and the Sudbury Neutrino Observatory—all now monitoring the transition regime between low-energy (vacuumlike) and high-energy (matter-dominated) flavor conversions—we consider the role of subdominant dynamical terms induced by new flavor-changing interactions. We find that the presence of such perturbations with strength ˜10-1GF is now favored, offering a better description of the anomalous behavior suggested by the new results, whose spectrum shows no sign of the typical low-energy upturn predicted by the standard Mikheyev-Smirnov-Wolfenstein (MSW) mechanism. Our findings, if interpreted in a 2-flavor scheme, provide a hint of such new interactions at the ˜2σ level, which is rather robust with respect to 3-flavor effects possibly induced by nonzero θ13.

  5. ALGUNAS PAUTAS PARA LA ESCRITURA DE ARTÍCULOS CIENTÍFICOS SOME HINTS FOR WRITING SCIENTIFIC PAPERS

    Directory of Open Access Journals (Sweden)

    Carlos M Zapata

    2008-06-01

    Full Text Available El objetivo de este artículo es presentar, a aquellos investigadores neófitos, una serie de pautas que faciliten los procesos de escritura y publicación de manuscritos en revistas científicas de corriente principal. En la comunidad científica, una investigación sólo se completa cuando los resultados se socializan a través de artículos en revistas arbitradas que garanticen la originalidad, importancia y validez científica de los hallazgos reportados. Consecuentemente, es necesario que los investigadores desarrollen destrezas y habilidades en la escritura científica. Sin embargo, el proceso de preparación de un manuscrito, desde su fase inicial hasta su publicación final, suele ser largo y difícil, debido a algunos factores clave que tienen influencia sobre su calidad. Este artículo, suministra lineamientos generales sobre la preparación de manuscritos y entrega, también, pautas alrededor de las buenas prácticas de escritura de artículos con miras a facilitar la revisión por parte de los árbitros. En este sentido, este trabajo constituye aporte para quienes se inician en la difusión de la investigación científica.The objective of this paper is to present, to those neophyte researchers, a set of hints that facilitate manuscript writing and publishing processes needed for high class scientific journals. In the scientific community, a research would only be completed when the results are shared through papers in peer-reviewed journals that guarantees the originality, importance and scientific validation of reported contributions. Consequently, researchers have the necessity to develop skills and abilities in scientific writing. However, the manuscript preparation process from the initial phase to the final publication is usually slow and difficult, due to some key factors having influence over its quality. In this paper, we present general guidelines about manuscript preparation and we give some hints about good scientific

  6. Hint of nonstandard Mikheyev-Smirnov-Wolfenstein dynamics in solar neutrino conversion

    International Nuclear Information System (INIS)

    Palazzo, Antonio

    2011-01-01

    Motivated by the recent low-threshold measurements of the solar 8 B neutrino spectrum performed by Borexino, Super-Kamiokande and the Sudbury Neutrino Observatory--all now monitoring the transition regime between low-energy (vacuumlike) and high-energy (matter-dominated) flavor conversions--we consider the role of subdominant dynamical terms induced by new flavor-changing interactions. We find that the presence of such perturbations with strength ∼10 -1 G F is now favored, offering a better description of the anomalous behavior suggested by the new results, whose spectrum shows no sign of the typical low-energy upturn predicted by the standard Mikheyev-Smirnov-Wolfenstein (MSW) mechanism. Our findings, if interpreted in a 2-flavor scheme, provide a hint of such new interactions at the ∼2σ level, which is rather robust with respect to 3-flavor effects possibly induced by nonzero θ 13 .

  7. Seven Hints for Primordial Black Hole Dark Matter arXiv

    CERN Document Server

    Clesse, Sebastien

    Seven observations point towards the existence of primordial black holes (PBH), constituting the whole or an important fraction of the dark matter in the Universe: the mass and spin of black holes detected by Advanced LIGO/VIRGO, the detection of micro-lensing events of distant quasars and stars in M31, the non-detection of ultra-faint dwarf satellite galaxies with radius below 15 parsecs, evidences for core galactic dark matter profiles, the correlation between X-ray and infrared cosmic backgrounds, and the existence of super-massive black holes very early in the Universe's history. Some of these hints are newly identified and they are all intriguingly compatible with the re-constructed broad PBH mass distribution from LIGO events, peaking on PBH mass $m_{\\rm PBH} \\approx 3 M_\\odot$ and passing all other constraints on PBH abundances. PBH dark matter also provides a new mechanism to explain the mass-to-light ratios of dwarf galaxies, including the recent detection of a diffuse galaxy not dominated by dark ma...

  8. Particle Swarm Optimization algorithms for geophysical inversion, practical hints

    Science.gov (United States)

    Garcia Gonzalo, E.; Fernandez Martinez, J.; Fernandez Alvarez, J.; Kuzma, H.; Menendez Perez, C.

    2008-12-01

    PSO is a stochastic optimization technique that has been successfully used in many different engineering fields. PSO algorithm can be physically interpreted as a stochastic damped mass-spring system (Fernandez Martinez and Garcia Gonzalo 2008). Based on this analogy we present a whole family of PSO algorithms and their respective first order and second order stability regions. Their performance is also checked using synthetic functions (Rosenbrock and Griewank) showing a degree of ill-posedness similar to that found in many geophysical inverse problems. Finally, we present the application of these algorithms to the analysis of a Vertical Electrical Sounding inverse problem associated to a seawater intrusion in a coastal aquifer in South Spain. We analyze the role of PSO parameters (inertia, local and global accelerations and discretization step), both in convergence curves and in the a posteriori sampling of the depth of an intrusion. Comparison is made with binary genetic algorithms and simulated annealing. As result of this analysis, practical hints are given to select the correct algorithm and to tune the corresponding PSO parameters. Fernandez Martinez, J.L., Garcia Gonzalo, E., 2008a. The generalized PSO: a new door to PSO evolution. Journal of Artificial Evolution and Applications. DOI:10.1155/2008/861275.

  9. Modelling magnetic islands in the H-1NF heliac with the hint code

    International Nuclear Information System (INIS)

    Lloyd, S.S.; Gardner, H.J.

    1999-01-01

    Full text: Recent progress in the theoretical modelling of the effects of plasma pressure on the growth and change in geometry of magnetic islands in the H-1NF Heliac will be reviewed. The HINT magnetohydrodynamic equilibrium code, which has become a standard workhorse in the stellarator community for problems of this type, has been modified to incorporate an interpolation algorithm which significantly accelerates its convergence. This has enabled the critical evaluation of earlier results, and of some conventional wisdom. In many ways the treatment of magnetic islands in low shear fusion reactors, such as H-1NF, is an ideal case study in computational science - the devil is in the details and the devil is important: the existence or otherwise of island self-healing at reactor pressures could significantly affect the design of future experiments. (author)

  10. HEALTH INFO SANTÉ – REMINDER ANNUAL DEDUCTIBLE AND REIMBURSEMENT CLAIMS HINTS FOR USE

    CERN Multimedia

    CHIS Board

    2000-01-01

    Information from the CHIS Board and the Human Resources Division:Annual deductible and reimbursement claims: hints for useOne should bear in mind that the annual deductible is an amount (currently CHF 100) charged automatically by the Administrator of the scheme for every adult aged 18 and above. This is what happens: The amount is deducted annually for all medical services received over a calendar year.It is triggered by the date of the treatment and neither by the date of the bill nor that of the reimbursement claim.In other words, if you receive medical treatment in December for the first time in a given year, the CHF 100 will be deducted from the claim for that treatment. So, except for urgent cases, it would be better to wait till the following month, thus avoiding one annual deductible.It is also worth remembering that the cost of processing our reimbursement claims - and there were 54, 000 in 1999 - is part of the cost of our insurance.Help keep administrative costs down: do not submit reimbursement cl...

  11. The human interactome knowledge base (hint-kb): An integrative human protein interaction database enriched with predicted protein–protein interaction scores using a novel hybrid technique

    KAUST Repository

    Theofilatos, Konstantinos A.

    2013-07-12

    Proteins are the functional components of many cellular processes and the identification of their physical protein–protein interactions (PPIs) is an area of mature academic research. Various databases have been developed containing information about experimentally and computationally detected human PPIs as well as their corresponding annotation data. However, these databases contain many false positive interactions, are partial and only a few of them incorporate data from various sources. To overcome these limitations, we have developed HINT-KB (http://biotools.ceid.upatras.gr/hint-kb/), a knowledge base that integrates data from various sources, provides a user-friendly interface for their retrieval, cal-culatesasetoffeaturesofinterest and computesaconfidence score for every candidate protein interaction. This confidence score is essential for filtering the false positive interactions which are present in existing databases, predicting new protein interactions and measuring the frequency of each true protein interaction. For this reason, a novel machine learning hybrid methodology, called (Evolutionary Kalman Mathematical Modelling—EvoKalMaModel), was used to achieve an accurate and interpretable scoring methodology. The experimental results indicated that the proposed scoring scheme outperforms existing computational methods for the prediction of PPIs.

  12. W7-X vacuum and finite-β magnetic field structure resolved with the HINT 3D equilibrium code

    International Nuclear Information System (INIS)

    Hayashi, T.; Merkel, P.; Nuehrenberg, J.; Schwenn, U.

    1994-01-01

    The 3D equilibrium code HINT allows the direct investigation of finite-β effects on sizes and phases of islands in genuinely 3D configurations like the W7-X stellarator planned by the Max-Planck-Institut fuer Plasmaphysik in Germany. The code does not require the existence of nested flux surfaces. This, in contrast to the inverse formulation used in the VMEC code, leads to a considerably more complex computational goal. The HINT code combines some crucial features reducing the numerical problems and the computational effort to such an extent as to allow computation of 3D equilibria at finite-β with magnetic islands. The code is based on a two-step procedure: Starting from a given B and an initial pressure, the iteration technique for the pressure advancement is differencing in an artificial time with an explicit 4th order scheme, or - alternatively for resolving the island topology - field lines starting from all gridpoints are followed long enough to allow pressure equalization along these. B.∇p 0, for fixed B. In a second step, p is kept fixed and B is advanced with an artificial time for solving ∇p - jxB = 0 under the constraint of vanishing toroidal current J. The differential equations are discretized in space with 4th order difference approximations on an Eulerian grid spanned by a rectangular box whose toroidal rotation law follows the W7-X geometry. The two sub-iteration steps are repeated until the force balance is satisfied to an appropriate accuracy. The boundaries (where the boundary conditions are prescribed) are far enough away from the last closed magnetic surface, thus guaranteeing the motion of the plasma column not being constrained by the boundary conditions. Due to the stellarator symmetry in the toroidal direction only half of an equilibrium period is computed, using modified periodic boundary conditions guaranteeing the 4th order of the spatial discretization. (author) 5 refs., 4 figs

  13. AUTOSOMAL RECESSIVE PERIPHERAL NEUROPATHY WITH NEUROMYOTONIA (ARAN-NM: DESCRIPTION OF A CLINICAL CASE CONFIRMED BY A MUTATION IN THE HINT1 GENE

    Directory of Open Access Journals (Sweden)

    Olga A. Klochkova

    2017-01-01

    Full Text Available Autosomal recessive  peripheral neuropathy with neuromyotonia  (ARAN-NM  is a relatively newly described  disease associated  with mutations  in the HINT1 gene.  It accounts  for a significant  part of the poorly  differentiated  forms  of axonal polyneuropathies.  We present the first in Russia description of the genetically confirmed case of ARAN-NM in a boy aged 14 years and 11 months without the hereditary-tainted anamnesis. On presentation,  the patient experienced  progressive  distal muscular weakness, asymmetric foot deformity,  gait disorders  and minimal manifestations  of neuromyotonia  (stiffness  in the fingers.  During examination,  we detected an increase in the level of creatine phosphokinase up to 635 U/l, a disturbance of conduction of motor and, to a lesser extent, sensory fibers  of  the  peripheral  nerves  (according  to  the  stimulation  electromyography,  EMG,  denervation-reinnervation  changes,  single positive acute waves, fibrillation potentials, complex repeated discharge (according to the data of needle EMG. In the study of exome, a homozygous mutation c.110G>C, p.R37P was determined in exon 01 of the HINT1 gene, which confirmed the presence of ARAN-NM. A molecular-genetic  examination of the patient's immediate relatives was carried out. The described case is compared with literature data. An overview of currently available information on ARAN-NM is provided. Diagnostic criteria of the disease are presented.

  14. Hints on cost- and energy saving during lime-sand brick production; Hinweise zur Kosten- und Energieeinsparung bei der Kalksandstein-Produktion

    Energy Technology Data Exchange (ETDEWEB)

    Eden, W.

    2001-05-01

    The publication contains hints for reduction of energy consumption and cost in lime-sand brick production. The information was compiled by Bundesverband Kalksandsteinindustrie e.V. and was derived from technical discussions of the master seminars on production technology of the years 1995 - 2000, consultations form member organizations, or from other sources. [German] Diese Arbeit ist eine Zusammenstellung von Hinweisen zur Reduzierung des Energieverbrauchs und der Kostensenkung bei der KS-Produktion und soll eine Hilfestellung bei entsprechenden Rationalisierungsmassnahmen in den Mitgliedsunternehmen sein. Die hier aufgefuehrten Hinweise und Anregungen entstammen den Fachdiskussionen der Meisterseminare zur Produktionstechnik aus den Jahren 1995 bis 2000, Beratungsgespraechen fuer Mitgliedsunternehmen oder wurden dem Bundesverband Kalksandsteinindustrie eV freundlicherweise fuer die Gemeinschaftsarbeit zur Verfuegung gestellt. (orig.)

  15. Patient-provider discussion of online health information: results from the 2007 Health Information National Trends Survey (HINTS).

    Science.gov (United States)

    Chung, Jae Eun

    2013-01-01

    Increasing numbers of people have turned to the Internet for health information. Little has been done beyond speculation to empirically investigate patients' discussion of online health information with health care professionals (HCPs) and patients' perception of HCPs' reactions to such discussion. The author analyzed data from the 2007 Health Information National Trends Survey (HINTS) to identify the characteristics of patients (a) who search for health information on the Internet, (b) who discuss the information found on the Internet with HCPs, and (c) who positively assess HCPs' reaction to the online information. Findings show that men were more likely than were women to have a conversation on online information with HCPs. It is unfortunate that patients who had trouble understanding or trusting online health information were no more likely to ask questions to or seek guidance from HCPs. Reactions of HCPs to online information were perceived as particularly negative by certain groups of patients, such as those who experienced poor health and those who had more concerns about the quality of their searched information. Results are discussed for their implications for patient empowerment and patient-HCP relationships.

  16. Profiling and quantitative evaluation of three Nickel-Coated magnetic matrices for purification of recombinant proteins: lelpful hints for the optimized nanomagnetisable matrix preparation

    Directory of Open Access Journals (Sweden)

    Zarei Saeed

    2011-08-01

    Full Text Available Abstract Background Several materials are available in the market that work on the principle of protein magnetic fishing by their histidine (His tags. Little information is available on their performance and it is often quoted that greatly improved purification of histidine-tagged proteins from crude extracts could be achieved. While some commercial magnetic matrices could be used successfully for purification of several His-tagged proteins, there are some which have been proved to operate just for a few extent of His-tagged proteins. Here, we address quantitative evaluation of three commercially available Nickel nanomagnetic beads for purification of two His-tagged proteins expressed in Escherichia coli and present helpful hints for optimized purification of such proteins and preparation of nanomagnetisable matrices. Results Marked differences in the performance of nanomagnetic matrices, principally on the basis of their specific binding capacity, recovery profile, the amount of imidazole needed for protein elution and the extent of target protein loss and purity were obtained. Based on the aforesaid criteria, one of these materials featured the best purification results (SiMAG/N-NTA/Nickel for both proteins at the concentration of 4 mg/ml, while the other two (SiMAC-Nickel and SiMAG/CS-NTA/Nickel did not work well with respect to specific binding capacity and recovery profile. Conclusions Taken together, functionality of different types of nanomagnetic matrices vary considerably. This variability may not only be dependent upon the structure and surface chemistry of the matrix which in turn determine the affinity of interaction, but, is also influenced to a lesser extent by the physical properties of the protein itself. Although the results of the present study may not be fully applied for all nanomagnetic matrices, but provide a framework which could be used to profiling and quantitative evaluation of other magnetisable matrices and also

  17. Perturbed Lepton-Specific Two-Higgs-Doublet Model Facing Experimental Hints for Physics beyond the Standard Model.

    Science.gov (United States)

    Crivellin, Andreas; Heeck, Julian; Stoffer, Peter

    2016-02-26

    BABAR, Belle, and LHCb Collaborations report evidence for new physics in B→Dτν and B→D^{*}τν of approximately 3.8σ. There is also the long lasting discrepancy of about 3σ in the anomalous magnetic moment of the muon, and the branching ratio for τ→μνν is 1.8σ (2.4σ) above the standard model expectation using the HFAG (PDG) values. Furthermore, CMS Collaboration finds hints for a nonzero decay rate of h→μτ. Interestingly, all these observations can be explained by introducing new scalars. In this Letter we consider these processes within a lepton-specific two-Higgs doublet model (i.e., of type X) with additional nonstandard Yukawa couplings. It is found that one can accommodate τ→μνν with modified Higgs-τ couplings. The anomalous magnetic moment of the muon can be explained if the additional neutral CP-even Higgs boson H is light (below 100 GeV). Also R(D) and R(D^{*}) can be easily explained by additional t-c-Higgs couplings. Combining these t-c couplings with a light H the decay rate for t→Hc can be in a testable range for the LHC. Effects in h→μτ are also possible, but in this case a simultaneous explanation of the anomalous magnetic moment of the muon is difficult due to the unavoidable τ→μγ decay.

  18. Higgs hints

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1991-10-15

    As well as dominating the news at the recent Joint International Lepton-Photon Symposium and Europhysics Conference on High Energy Physics in Geneva, results from the four big experiments - Aleph , Delphi, L3 and Opal - at CERN's big LEP electron-positron collider had far-reaching implications.

  19. Hint from the interfamily mass hierarchy: Two vectorlike families in the TeV range

    Science.gov (United States)

    Babu, K. S.; Pati, Jogesh C.; Stremnitzer, Hanns

    1995-03-01

    Two vectorlike familes QL,R=(U, D, N, E)L,R and Q'L,R=(U', D', N', E')L,R with masses of order 1 TeV, one of which is a doublet of SU(2)L and the other a doublet of SU(2)R, have been predicted to exist, together with the three observed chiral families, in the context of a viable and economical SUSY preon model. The model itself possesses many attractive features which include explanations of the origins of (i) diverse mass scales, (ii) family replication, (iii) protection of the masses of the composite quarks and leptons compared to their compositeness scales, and (iv) interfamily mass hierarchy. The existence of the two vectorlike familes, a prediction of the model, turns out to be crucial especially for an explanation of the interfamily mass hierarchy (IFMH). Given the simplicity of the explanation, the observed IFMH in turn appears to us to be a strong hint in favor of the existence of the two vectorlike families. This paper is devoted to a detailed study of the expected masses, mixings and decay modes of the fermions belonging to the two vectorlike families, in the context of the SUSY preon model, with the inclusion of the renormalization effects due to the standard model gauge interactions. Including QCQ renormalization effects, the masses of the vectorlike quarks are expected to lie in the range of 500 GeV to about 2.5 TeV, while those of the vectorlike leptons are expected to be in the range of 200 GeV to 1 TeV. Their mass pattern and decay modes exhibit certain distinguishing features and characteristic signals. For example, when the CERN LHC and, possibly a future version of the SSC are built, pair production of the vectorlike quarks would lead to systems such as (bb¯+4Z+W+W-) and (bb¯+2Z+W+W-), while an e-e+ linear collider (NLC) of suitable energy can produce appreciably a single neutral heavy lepton N together, with ντ, followed by the decay of N into (Z+ντ)-->(e-e+)+ντ. This last signal may conceivably materialize even at CERN LEP 200 if N is

  20. Oral administration of heat-killed Lactobacillus gasseri OLL2809 reduces cedar pollen antigen-induced peritoneal eosinophilia in Mice.

    Science.gov (United States)

    Sashihara, Toshihiro; Ikegami, Shuji; Sueki, Natsuko; Yamaji, Taketo; Kino, Kohsuke; Taketomo, Naoki; Gotoh, Minoru; Okubo, Kimihiro

    2008-12-01

    Lactobacillus gasseri OLL2809 strongly stimulates the production of interleukin (IL)-12 (p70) by innate immune cells. Thus, it is expected to ameliorate allergic diseases. We investigated whether the oral administration of heat-killed L. gasseri OLL2809 suppressed eosinophilia in cedar pollen antigen-challenged mice. BALB/c mice sensitized with Japanese cedar pollen extract were intraperitoneally challenged with the same extract. The mice were orally given heat-killed L. gasseri OLL2809 at doses of 0.5, 1, or 2mg/day throughout the experimental period (21 d). After 24 hours of the challenge, the eosinophil number and cytokine levels in the peritoneal lavage fluid and the serum antigen-specific IgG levels were determined. On administering varying amounts of heat-killed L. gasseri OLL2809, the number of eosinophils among the total number of cells was significantly reduced in all groups. In addition, the eosinophil number significantly decreased, and the eosinophil-suppression rate significantly increased by 44% in the 2-mg group. Although the serum immunoglobulin (Ig) G2a and IgG1 levels were not affected, the IgG2a/IgG1 ratio increased significantly in the 2-mg group compared with that of the control group. Furthermore, the administration of heat-killed L. gasseri OLL2809 resulted in the induction of IL-2 and reduction in granulocyte-macrophage colony-stimulating factor levels in peritoneal lavage fluid. We demonstrated that the oral administration of heat-killed L. gasseri OLL2809 suppresses eosinophilia via the modulation of Th1/Th2 balance. These observations suggested that heat-killed L. gasseri OLL2809 might potentially ameliorate the increased number of eosinophils in patients with Japanese cedar pollinosis.

  1. Oral Administration of Heat-Killed Lactobacillus gasseri OLL2809 Reduces Cedar Pollen Antigen-Induced Peritoneal Eosinophilia in Mice

    Directory of Open Access Journals (Sweden)

    Toshihiro Sashihara

    2008-01-01

    Conclusions: We demonstrated that the oral administration of heat-killed L. gasseri OLL2809 suppresses eosinophilia via the modulation of Th1/Th2 balance. These observations suggested that heat-killed L. gasseri OLL2809 might potentially ameliorate the increased number of eosinophils in patients with Japanese cedar pollinosis.

  2. Enhanced natural killer cell activation by exopolysaccharides derived from yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1.

    Science.gov (United States)

    Makino, Seiya; Sato, Asako; Goto, Ayako; Nakamura, Marie; Ogawa, Miho; Chiba, Yoshika; Hemmi, Jun; Kano, Hiroshi; Takeda, Kazuyoshi; Okumura, Ko; Asami, Yukio

    2016-02-01

    Yogurt is generally recognized as a beneficial food for our health, but research into its physiological effects has focused mainly on intestinal dysfunctions such as constipation and diarrhea. We previously found yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 (hereafter OLL1073R-1) could reduce risks of catching the common cold and flu in human trials. It was assumed that immunostimulatory exopolysaccharide (EPS) produced from OLL1073R-1 play an important role in this context. However, few studies have examined the immunostimulatory effects of traditional Bulgarian yogurts fermented with different strains of lactobacilli and their metabolites. Therefore, we screened 139 L. delbrueckii ssp. bulgaricus strains and identified OLL1073R-1 as the most robust producer of EPS. This strain was also the only strain that induced the production of IFN-γ in vitro. Oral administration of the EPS or yogurt fermented with OLL1073R-1 and Streptococcus thermophilus OLS3059 (OLL1073R-1 yogurt) augmented natural killer (NK) cell activity and induced IFN-γ production in spleen cells in mice, whereas 2 other yogurts fermented with other strains had no effect on NK cell activity. Cellular preparations of the OLL1073R-1 strain also slightly augmented NK cell activity, but were less effective than EPS itself. The EPS-dependent stimulation of NK cell activity was abrogated in IFN-γ knockout mice and in myeloid differentiation factor 88 knockout mice. Furthermore, IFN-γ production from spleen cells stimulated with EPS was completely blocked with both anti-IL-12 and anti-IL-18 antibodies in vitro. These findings suggest that NK cell activation by OLL1073R-1 yogurt is EPS-dependent, occurs via IL-12- and IL-18-mediated IFN-γ production, and requires myeloid differentiation factor 88. We showed that traditional Bulgarian yogurt could exert immunostimulatory effects by selecting starter strains and part of the mechanisms depend on IFN-γ inducible EPS produced

  3. Hints for Diagnosis

    DEFF Research Database (Denmark)

    Poulsen, Lars K

    2015-01-01

    /or caretakers. Based on this, a provisional decision to pursue a food allergy diagnosis may be made after carefully considering other possible reasons for an adverse reaction to a food: aversion, infection, intoxication, or an underlying metabolic disease. To respond to the next question, the anamnesis...

  4. Lactobacillus bulgaricus OLL1181 activates the aryl hydrocarbon receptor pathway and inhibits colitis

    Science.gov (United States)

    Takamura, Takeyuki; Harama, Daisuke; Fukumoto, Suguru; Nakamura, Yuki; Shimokawa, Naomi; Ishimaru, Kayoko; Ikegami, Shuji; Makino, Seiya; Kitamura, Masanori; Nakao, Atsuhito

    2011-01-01

    Increasing evidence suggests that the aryl hydrocarbon receptor (AhR) pathway has an important role in the regulation of inflammatory responses. Most recently, we have shown that the activation of the AhR pathway by a potent AhR agonist inhibits the development of dextran sodium sulfate (DSS)-induced colitis, a model of human ulcerative colitis, by the induction of prostaglandin E2 (PGE2) in the large intestine. Because several strains of probiotic lactic acid bacteria have been reported to inhibit DSS-induced colitis by unidentified mechanisms, we hypothesized that particular strains of lactic acid bacterium might have the potential to activate the AhR pathway, thereby inhibiting DSS-induced colitis. This study investigated whether there are specific lactic acid bacterial strains that can activate the AhR pathway, and if so, whether this AhR-activating potential is associated with suppression of DSS-induced colitis. By using AhR signaling reporter cells, we found that Lactobacillus bulgaricus OLL1181 had the potential to activate the AhR pathway. OLL1181 also induced the mRNA expression of cytochrome P450 family 1A1 (CYP1A1), a target gene of the AhR pathway, in human colon cells, which was inhibited by the addition of an AhR antagonist, α-naphthoflavon (αNF). In addition, mice treated orally with OLL1181 showed an increase in CYP1A1 mRNA expression in the large intestine and amelioration of DSS-induced colitis. Thus, OLL1181 can induce activation of the intestinal AhR pathway and inhibit DSS-induced colitis in mice. This strain of lactic acid bacterium has therefore the potential to activate the AhR pathway, which may be able to suppress colitis. PMID:21321579

  5. Smartphone Ownership Among US Adult Cigarette Smokers: 2014 Health Information National Trends Survey (HINTS) Data.

    Science.gov (United States)

    Heffner, Jaimee L; Mull, Kristin E

    2017-08-31

    Despite increasing interest in smartphone apps as a platform for delivery of tobacco cessation interventions, no previous studies have evaluated the prevalence and characteristics of smokers who can access smartphone-delivered interventions. To guide treatment development in this new platform and to evaluate disparities in access to smartphone-delivered interventions, we examined associations of smartphone ownership with demographics, tobacco use and thoughts about quitting, other health behaviors, physical and mental health, health care access, and Internet and technology utilization using a nationally representative sample of US adult smokers. Data were from the National Cancer Institute's 2014 Health Information National Trends Survey 4 (HINTS 4), Cycle 4. This mailed survey targeted noninstitutionalized individuals aged 18 years or older using two-stage stratified random sampling. For this analysis, we restricted the sample to current smokers with complete data on smartphone ownership (n=479). Nearly two-thirds (weighted percent=63.8%, 248/479) of smokers reported owning a smartphone. Those who were younger (P<.001), employed (P=.002), never married (P=.002), and had higher education (P=.002) and income (P<.001) had the highest rates of ownership. Smartphone owners did not differ from nonowners on frequency of smoking, recent quit attempts, or future plans to quit smoking, although they reported greater belief in the benefits of quitting (P=.04). Despite being equally likely to be overweight or obese, smartphone owners reported greater fruit and vegetable consumption (P=.03) and were more likely to report past-year efforts to increase exercise (P=.001) and to lose weight (P=.02). No differences in health care access and utilization were found. Smartphone owners reported better physical and mental health in several domains and higher access to and utilization of technology and the Internet, including for health reasons. Smartphone ownership among smokers mirrors

  6. Effects of Lactobacillus plantarum Strain OLL2712 Culture Conditions on the Anti-inflammatory Activities for Murine Immune Cells and Obese and Type 2 Diabetic Mice.

    Science.gov (United States)

    Toshimitsu, T; Ozaki, S; Mochizuki, J; Furuichi, K; Asami, Y

    2017-04-01

    Studies on the health-promoting effects of lactic acid bacteria (LAB) are numerous, but few provide examples of the relationship between LAB function and culture conditions. We verified the effect of differences in culture conditions on Lactobacillus plantarum OLL2712 functionality; this strain exhibits anti-inflammatory activity and preventive effects against metabolic disorders. We measured interleukin-10 (IL-10) and IL-12 production in murine immune cells treated with OLL2712 cells prepared under various culture conditions. The results showed that the IL-10-inducing activities of OLL2712 cells on murine immune cells differed dramatically between OLL2712 groups at different culture phases and using different culture medium components, temperatures, and neutralizing pHs. In particular, exponential-phase cells had much more IL-10-inducing activity than stationary-phase cells. We confirmed that the Toll-like receptor 2 (TLR2) stimulation activity of OLL2712 cells depended on culture conditions in conjunction with IL-10-inducing activity. We also demonstrated functional differences by culture phases in vivo ; OLL2712 cells at exponential phase had more anti-inflammatory activity and anti-metabolic-disorder effects on obese and diabetic mice than those by their stationary-phase counterparts. These results suggest that culture conditions affect the functionality of anti-inflammatory LAB. IMPORTANCE While previous studies demonstrated that culture conditions affected the immunomodulatory properties of lactic acid bacteria (LAB), few have comprehensively investigated the relationship between culture conditions and LAB functionality. In this study, we demonstrated several culture conditions of Lactobacillus plantarum OLL2712 for higher anti-inflammatory activity. We also showed that culture conditions concretely influenced the health-promoting functions of OLL2712 in vivo , particularly against metabolic disorders. Further, we characterized a novel mechanism by which

  7. Oral administration of Lactobacillus delbrueckii subspecies bulgaricus OLL1073R-1 suppresses inflammation by decreasing interleukin-6 responses in a murine model of atopic dermatitis.

    Science.gov (United States)

    Kano, Hiroshi; Kita, Junko; Makino, Seiya; Ikegami, Shuji; Itoh, Hiroyuki

    2013-06-01

    The oral intake of Lactobacillus spp. can provide beneficial effects to the host by modulating the immune response. Atopic dermatitis (AD) is an allergic inflammatory disease mediated by various immune responses. In this study, we examined the effect of a Lactobacillus strain, Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 (OLL1073R-1), on AD development in a murine model of AD that was developed by the topical application of mite antigen in NC/Nga mice. The oral intake of heat-killed OLL1073R-1 cells inhibited both the development of dermatitis and the elevation of an acute inflammation marker, serum amyloid A. Another bacterial strain, Lactobacillus rhamnosus OLL2984, exerted no inhibitory effects on dermatitis. The oral intake of heat-killed OLL1073R-1 cells also attenuated secretion of IL-6 from lymph node cells in response to mite antigen and reduced IL-6 levels in inflamed tissues, such as auricles. Production of IFN-γ or IL-4 was not influenced by OLL1073R-1 intake. We also found that inhibition of IL-6 signaling by gp130-Fc (a fusion protein consisting of the extracellular portion of glycoprotein 130 fused to the Fc region of human IgG1) markedly decreased the severity of dermatitis in NC/Nga mice. Moreover, secretion of IL-6 by lymph node cells was augmented in NC/Nga mice compared with that in BALB/c mice. These results indicate that IL-6 plays an essential role in the development of dermatitis in the NC/Nga mouse model of AD, and that OLL1073R-1 inhibits dermatitis, at least in part, by suppressing the IL-6 response. Copyright © 2013 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  8. Kaks kaptenit / Krister Kivi

    Index Scriptorium Estoniae

    Kivi, Krister, 1975-

    2007-01-01

    Väliseestlased Mart ja Peter Hint on teinud silmapaistvat karjääri Ameerika Lennunduses. Mart Hint töötab Boening 767 kaptenina lennukompaniis Delta, Peter Hint töötab lennukompaniis American Airlines

  9. Methodology for the Model-based Small Area Estimates of Cancer-Related Knowledge - Small Area Estimates

    Science.gov (United States)

    The HINTS is designed to produce reliable estimates at the national and regional levels. GIS maps using HINTS data have been used to provide a visual representation of possible geographic relationships in HINTS cancer-related variables.

  10. Nonminimal hints for asymptotic safety

    Science.gov (United States)

    Eichhorn, Astrid; Lippoldt, Stefan; Skrinjar, Vedran

    2018-01-01

    In the asymptotic-safety scenario for gravity, nonzero interactions are present in the ultraviolet. This property should also percolate into the matter sector. Symmetry-based arguments suggest that nonminimal derivative interactions of scalars with curvature tensors should therefore be present in the ultraviolet regime. We perform a nonminimal test of the viability of the asymptotic-safety scenario by working in a truncation of the renormalization group flow, where we discover the existence of an interacting fixed point for a corresponding nonminimal coupling. The back-coupling of such nonminimal interactions could in turn destroy the asymptotically safe fixed point in the gravity sector. As a key finding, we observe nontrivial indications of stability of the fixed-point properties under the impact of nonminimal derivative interactions, further strengthening the case for asymptotic safety in gravity-matter systems.

  11. evaluation of total annual costs of heat exchanger networks using

    African Journals Online (AJOL)

    This study presents pinch analysis of some heat exchanger networks (HENs) problems using Hint integration (HINT) software. Three examples reported to have been solved using different approaches by various researchers to obtain the least possible total annual cost (TAC) were solved using the Hint software. In this work ...

  12. Collaboration and peer tutoring in chemistry laboratory education

    NARCIS (Netherlands)

    Ding, N.; Harskamp, E.G.

    2011-01-01

    The aim of this study is to examine the effectiveness of collaborative learning with hints and peer tutoring with hints, and individual learning with hints in chemistry laboratory education in a secondary school. A total of 96 eleventh graders participated in this study. The study has a randomized

  13. Adaptive filtering primer with Matlab

    CERN Document Server

    Poularikas, Alexander D

    2006-01-01

    INTRODUCTIONSignal ProcessingAn ExampleOutline of the TextDISCRETE-TIME SIGNAL PROCESSINGDiscrete Time SignalsTransform-Domain Representation of Discrete-Time SignalsThe Z-TransformDiscrete-Time SystemsProblemsHints-Solutions-SuggestionsRANDOM VARIABLES, SEQUENCES, AND STOCHASTIC PROCESSESRandom Signals and DistributionsAveragesStationary ProcessesSpecial Random Signals and Probability Density FunctionsWiener-Khinchin RelationsFiltering Random ProcessesSpecial Types of Random ProcessesNonparametric Spectra EstimationParametric Methods of power Spectral EstimationProblemsHints-Solutions-SuggestionsWIENER FILTERSThe Mean-Square ErrorThe FIR Wiener FilterThe Wiener SolutionWiener Filtering ExamplesProblemsHints-Solutions-SuggestionsEIGENVALUES OF RX - PROPERTIES OF THE ERROR SURFACEThe Eigenvalues of the Correlation MatrixGeometrical Properties of the Error SurfaceProblemsHints-Solutions-SuggestionsNEWTON AND STEEPEST-DESCENT METHODOne-Dimensional Gradient Search MethodSteepest-Descent AlgorithmProblemsHints-Sol...

  14. NNS computing facility manual P-17 Neutron and Nuclear Science

    International Nuclear Information System (INIS)

    Hoeberling, M.; Nelson, R.O.

    1993-11-01

    This document describes basic policies and provides information and examples on using the computing resources provided by P-17, the Neutron and Nuclear Science (NNS) group. Information on user accounts, getting help, network access, electronic mail, disk drives, tape drives, printers, batch processing software, XSYS hints, PC networking hints, and Mac networking hints is given

  15. Effect of Formic Acid on Exopolysaccharide Production in Skim Milk Fermentation by Lactobacillus delbrueckii subsp. bulgaricus OLL1073R-1.

    Science.gov (United States)

    Nishimura, Junko; Kawai, Yasushi; Aritomo, Ryota; Ito, Yoshiyuki; Makino, Seiya; Ikegami, Shuji; Isogai, Emiko; Saito, Tadao

    2013-01-01

    In yogurt, the formation of formate by Streptococcus thermophilus stimulates the activity of Lactobacillus delbrueckii subsp. bulgaricus (L. bulgaricus). However, there have been no reports how formic acid acts on the exopolysaccharide (EPS) production of L. bulgaricus. Here, the effect of formate on the EPS production in skim milk by L. bulgaricus OLL1073R-1 was investigated. After incubation for 24 hr with 100 mg/l formate, cell proliferation and lactic acid production were accelerated. The viable and total cell numbers were increased about ten- and four-fold, respectively. The amount of EPS in culture with formate (~116 µg/ml) was also four-fold greater than that of the control (~27 µg/ml). Although elongation of cells was observed at 6 hr of cultivation in both cultures, cells cultivated with formate returned to a normal shape after incubation for 24 hr. The sensitivity to cell wall hydrolase and composition of surface layer proteins, as well as the cell membrane fatty acid composition of L. bulgaricus OLL1073R-1, were not influenced by formate. However, differences were observed in intracellular fatty acid compositions and sensitivity to antibiotics. Cell length and surface damage returned to normal in cultures with formate. These observations suggest that formic acid is necessary for normal cell growth of L. bulgaricus OLL1073R-1 and higher EPS production.

  16. Practical Hints on Greek and Latin

    Science.gov (United States)

    Jopes, James

    1978-01-01

    A discussion of some of the difficulties and procedures in translating classical quotations occurring in a modern text. Some of the topics covered are: use of published translations, transliteration from ancient Greek, and non-classical idioms such as medieval and botanical Latin. (AMH)

  17. [Modifying our "obesogenic" environment: which hints?].

    Science.gov (United States)

    Masciangelo, M L; Golay, A

    2006-03-29

    Overweight is nowadays a major problem of public health in Switzerland. Swiss people eat too much, too much fat, sugar and salt! Most efficient public health strategies are global and also apply to environmental modifications, an important determinant to change individual behaviours. Today, our environment is "obesogenic": unlimited access to food, food industry marketing, lifestyle changes. As global programmes for smoking cessation and cardiovascular diseases prevention, it is urgent to propose interventions taking into account all environmental factors which could support individuals in their efforts of changes.

  18. Design Copyright: The Latest Judicial Hint

    OpenAIRE

    Scott Hemphill; Jeannie Suk

    2013-01-01

    The most intriguing aspect of the debate over fashion copyright is the occasion it presents for rethinking the expansive copyright law we currently have. C. Scott Hemphill (Columbia Law) & Jeannie Suk (Harvard Law)

  19. Taso Mähar : galerii / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Taso Mähari projekteeritud töödest. 1997. a. valminud restorani Exit sisekujundusest, mis pälvis Eesti Sisearhitektide Liidu aastapreemia. Metallist ja ühest tükist väljapainutatud toolist ja samas laadis tehtud diivanist aastast 1989, mis leidsid 1992. a. aastauudistena äramärkimist ajakirjas Abitare. T. Mähari kommentaarid. 3 värv. ill

  20. Observational hints on the Big Bounce

    International Nuclear Information System (INIS)

    Mielczarek, Jakub; Kurek, Aleksandra; Szydłowski, Marek; Kamionka, Michał

    2010-01-01

    In this paper we study possible observational consequences of the bouncing cosmology. We consider a model where a phase of inflation is preceded by a cosmic bounce. While we consider in this paper only that the bounce is due to loop quantum gravity, most of the results presented here can be applied for different bouncing cosmologies. We concentrate on the scenario where the scalar field, as the result of contraction of the universe, is driven from the bottom of the potential well. The field is amplified, and finally the phase of the standard slow-roll inflation is realized. Such an evolution modifies the standard inflationary spectrum of perturbations by the additional oscillations and damping on the large scales. We extract the parameters of the model from the observations of the cosmic microwave background radiation. In particular, the value of inflaton mass is equal to m = (1.7±0.6)·10 13 GeV. In our considerations we base on the seven years of observations made by the WMAP satellite. We propose the new observational consistency check for the phase of slow-roll inflation. We investigate the conditions which have to be fulfilled to make the observations of the Big Bounce effects possible. We translate them to the requirements on the parameters of the model and then put the observational constraints on the model. Based on assumption usually made in loop quantum cosmology, the Barbero-Immirzi parameter was shown to be constrained by γ < 1100 from the cosmological observations. We have compared the Big Bounce model with the standard Big Bang scenario and showed that the present observational data is not informative enough to distinguish these models

  1. Kerjav kunstnik / Anna Hints, Maria Rõhu

    Index Scriptorium Estoniae

    Hints, Anna, 1982-

    2011-01-01

    Tallinna Linnagaleriis oli 17.03.-10.04.2011 avatud Anna Hintsi ja Maria Rõhu näitus "Nälg". Autorid näituse taotlusest, raha taotlemisest, aktsioonist "Kerjav kunstnik", külastajate suhtumisest sellesse. Näituse aruanne

  2. HINTS IN OMABE BASED SCULPTURE INSTALLATIONS ...

    African Journals Online (AJOL)

    ASOGWA IFEANYI

    2017-02-02

    Feb 2, 2017 ... to develop both new methods of inquiry and appropriate forms of ... sculpture, music, dance, poetry, movement, dialogue and painting. ... were feared and respected by everybody in the society, including women and children.

  3. Masking Release for Igbo and English

    OpenAIRE

    Ebem, Deborah U.; Desloge, Joseph G.; Reed, Charlotte M.; Braida, Louis D.; Uguru, Joy O.

    2013-01-01

    In this research, we explored the effect of noise interruption rate on speech intelligibility. Specifically, we used the Hearing In Noise Test (HINT) procedure with the original HINT stimuli (English) and Igbo stimuli to assess speech reception ability in interrupted noise. For a given noise level, the HINT test provides an estimate of the signal-to-noise ratio (SNR) required for 50%-correct speech intelligibility. The SNR for 50%-correct intelligibility changes depending upon the interruptio...

  4. Sense of Accomplishment Is Modulated by a Proper Level of Instruction and Represented in the Brain Reward System.

    Science.gov (United States)

    Nakai, Tomoya; Nakatani, Hironori; Hosoda, Chihiro; Nonaka, Yulri; Okanoya, Kazuo

    2017-01-01

    Problem-solving can be facilitated with instructions or hints, which provide information about given problems. The proper amount of instruction that should be provided for learners is controversial. Research shows that tasks with intermediate difficulty induce the largest sense of accomplishment (SA), leading to an intrinsic motivation for learning. To investigate the effect of instructions, we prepared three instruction levels (No hint, Indirect hint, and Direct hint) for the same insight-problem types. We hypothesized that indirect instructions impose intermediate difficulty for each individual, thereby inducing the greatest SA per person. Based on previous neuroimaging studies that showed involvement of the bilateral caudate in learning and motivation, we expected SA to be processed in this reward system. We recruited twenty-one participants, and investigated neural activations during problem solving by functional magnetic resonance imaging (fMRI). We confirmed that the Indirect hint, which imposed intermediate difficulty, induced the largest SA among the three instruction types. Using fMRI, we showed that activations in the bilateral caudate and anterior cingulate cortex (ACC) were significantly modulated by SA. In the bilateral caudate, the indirect hint induced the largest activation, while the ACC seemed to reflect the difference between correct and incorrect trials. Importantly, such activation pattern was independent of notations (number or letter). Our results indicate that SA is represented in the reward system, and that the Indirect instruction effectively induces such sensation.

  5. Pitfalls and Rewards for Implementing Ocular Motor Testing in Acute Vestibular Syndrome: A Pilot Project.

    Science.gov (United States)

    Dumitrascu, Oana M; Torbati, Sam; Tighiouart, Mourad; Newman-Toker, David E; Song, Shlee S

    2017-03-01

    Isolated acute vestibular syndrome (iAVS) presentations to the emergency department (ED) pose management challenges, given the concerns for posterior circulation strokes. False-negative brain imaging may erroneously reassure clinicians, whereas HINTS-plus examination outperforms imaging to screen for strokes in iAVS. We studied the feasibility of implementing HINTS-plus testing in the ED, aiming to reduce neuroimaging in patients with iAVS. We launched an institutional Quality Improvement initiative, using DMAIC methodology. The outcome measures [proportion of iAVS subjects who had HINTS-plus examinations and underwent neuroimaging by computed tomography/magnetic resonance imaging (CT/MRI)] were compared before and after the established intervention. The intervention consisted of formal training for neurologists and emergency physicians on how to perform, document, and interpret HINTS-plus and implementation of novel iAVS management algorithm. Neuroimaging was not recommended if HINTS-plus suggested peripheral vestibular etiology. If a central process was suspected, brain MRI/MR angiogram was performed. Head CT was reserved only for thrombolytic time-window cases. In the first 2 months postimplementation, HINTS-plus testing performance by neurologists increased from 0% to 80% (P=0.007), and by ED providers from 0% to 9.09% (P=0.367). Head CT scans were reduced from 18.5% to 6.25%. Brain MRI use was reduced from 51.8% to 31.2%. About 60% of the iAVS subjects were discharged from the ED; none were readmitted or had another ED presentation in the ensuing 30 days. Implementation of HINTS-plus evaluation in the ED is valuable and feasible for neurologists, but challenging for emergency physicians. Future studies should determine the "dose-response" curve of educational interventions.

  6. Kunstiülikool on nagu pioneeride palee kunstiring / Vilen Künnapu, Meeli Truu, Eerik Olle...[jt.] ; interv. Gea Velthut-Sokka

    Index Scriptorium Estoniae

    1999-01-01

    Arhitektid V. Künnapu ja M. Truu, sisearhitektid I.-E. Schneider, E. Olle ja M. Peri ning kinnisvaraarendaja A. Aavik vastavad küsimustele, millises ülikoolis nad omandaksid eriala, kui nad oleksi praegu tudengid, Eestis saadava hariduse konkurentsivõimelisuse kohta maailmas, mida nad tahaksid praegu enda täiendamiseks õppida?

  7. Network Security Risks of Online Social Networking in the Workplace

    Science.gov (United States)

    2013-11-01

    Facebook explains pornographic shock spam, hints at browser vulnera- bility, nakedsecurity. URL – http://nakedsecurity.sophos.com/2011/11/16/ facebook...explains- pornographic -shock-spam-hints-at-browser-vul nerability/. 22 UNCLASSIFIED UNCLASSIFIED DSTO–GD–0772 44. Blatz, J. (2011) CSRF: attack and

  8. HINT-KB: The human interactome knowledge base

    KAUST Repository

    Theofilatos, Konstantinos A.; Dimitrakopoulos, Christos M.; Kleftogiannis, Dimitrios A.; Moschopoulos, Charalampos N.; Papadimitriou, Stergios; Likothanassis, Spiridon D.; Mavroudi, Seferina P.

    2012-01-01

    Proteins and their interactions are considered to play a significant role in many cellular processes. The identification of Protein-Protein interactions (PPIs) in human is an open research area. Many Databases, which contain information about

  9. Recommender System for Learning SQL Using Hints

    Science.gov (United States)

    Lavbic, Dejan; Matek, Tadej; Zrnec, Aljaž

    2017-01-01

    Today's software industry requires individuals who are proficient in as many programming languages as possible. Structured query language (SQL), as an adopted standard, is no exception, as it is the most widely used query language to retrieve and manipulate data. However, the process of learning SQL turns out to be challenging. The need for a…

  10. Tunne bossanova plaadiümbriselt / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2004-01-01

    Kahekorruseline eramu (285 m2), mille merepoolne sein on klaasist. Läbiv idee - silmside loodusega. Arhitekt ja sisearhitekt Tarmo Piirmets, tema kommentaar. Ill.: I ja II korruse plaan, 13 värv. vaadet

  11. Nursing knowledge: hints from the placebo effect.

    Science.gov (United States)

    Zanotti, Renzo; Chiffi, Daniele

    2017-07-01

    Nursing knowledge stems from a dynamic interplay between population-based scientific knowledge (the general) and specific clinical cases (the particular). We compared the 'cascade model of knowledge translation', also known as 'classical biomedical model' in clinical practice (in which knowledge gained at population level may be applied directly to a specific clinical context), with an emergentist model of knowledge translation. The structure and dynamics of nursing knowledge are outlined, adopting the distinction between epistemic and non-epistemic values. Then, a (moderately) emergentist approach to nursing knowledge is proposed, based on the assumption of a two-way flow from the general to the particular and vice versa. The case of the 'placebo effect' is analysed as an example of emergentist knowledge. The placebo effect is usually considered difficult to be explained within the classical biomedical model, and we underscore its importance in shaping nursing knowledge. In fact, nurses are primarily responsible for administering placebo in the clinical setting and have an essential role in promoting the placebo effect and reducing the nocebo effect. The beliefs responsible for the placebo effect are as follows: (1) interactive, because they depend on the relationship between patients and health care professionals; (2) situated, because they occur in a given clinical context related to certain rituals; and (3) grounded on higher order beliefs concerning what an individual thinks about the beliefs of others. It is essential to know the clinical context and to understand other people's beliefs to make sense of the placebo effect. The placebo effect only works when the (higher order) beliefs of doctors, nurses and patients interact in a given setting. Finally, we argue for a close relationship between placebo effect and nursing knowledge. © 2016 John Wiley & Sons Ltd.

  12. Election Year Hints at Shifts for Unions

    Science.gov (United States)

    Honawar, Vaishali; Keller, Bess

    2008-01-01

    The National Education Association is poised for a change in leadership this year as its president of six years, Reg Weaver, bumps up against term limits. Now, speculation is widespread that Edward J. McElroy, his counterpart at the American Federation of Teachers, might not seek re-election in July. The possible exit of Mr. McElroy--and the…

  13. Unsupervised MDP Value Selection for Automating ITS Capabilities

    Science.gov (United States)

    Stamper, John; Barnes, Tiffany

    2009-01-01

    We seek to simplify the creation of intelligent tutors by using student data acquired from standard computer aided instruction (CAI) in conjunction with educational data mining methods to automatically generate adaptive hints. In our previous work, we have automatically generated hints for logic tutoring by constructing a Markov Decision Process…

  14. Web-Based Quiz-Game-Like Formative Assessment: Development and Evaluation

    Science.gov (United States)

    Wang, Tzu-Hua

    2008-01-01

    This research aims to develop a multiple-choice Web-based quiz-game-like formative assessment system, named GAM-WATA. The unique design of "Ask-Hint Strategy" turns the Web-based formative assessment into an online quiz game. "Ask-Hint Strategy" is composed of "Prune Strategy" and "Call-in Strategy".…

  15. Oral lichen planus (OLP), oral lichenoid lesions (OLL), oral dysplasia, and oral cancer: retrospective analysis of clinicopathological data from 2002-2011.

    Science.gov (United States)

    Casparis, S; Borm, J M; Tektas, S; Kamarachev, J; Locher, M C; Damerau, G; Grätz, K W; Stadlinger, B

    2015-06-01

    This 10-year retrospective study analyzed the incidence of malignant transformation of oral lichen planus (OLP). The study also included dysplasia and oral lichenoid lesion (OLL) in the initial biopsy as a potential differential diagnosis. A total of 692 scalpel biopsies were taken from 542 patients (207 [38.2%] men and 335 [61.8%] women). Clinical and histopathological parameters were analyzed. The parameters gender (p = 0.022) and smoking behavior (p oral squamous cell carcinoma (OSCC). Smoking and joint disease appeared to be significant risk factors. Treatment with tretinoin in different concentrations (0.005-0.02%) significantly improved diagnosis. Twelve patients (8 female, 4 male) showed malignant transformation to OSCC within an average period of 1.58 years. The malignant transformation rate (MTR) was higher for OLL (4.4%) than OLP (1.2%). If the first biopsy showed intraepithelial neoplasia, the risk of developing OSCC increased (by 3.5% for squamous intraepithelial neoplasia (SIN) II and by 6.7% for SIN III). Although we cannot rule out that OLP is a premalignant oral condition, we can confirm that OLP had the lowest MTR of all diagnoses.

  16. Intracellular pH distribution as a cell health indicator in Saccharomyces cerevisiae

    DEFF Research Database (Denmark)

    Aabo, Thomas; Glückstad, Jesper; Siegumfeldt, Henrik

    2011-01-01

    .d.(pHint)) to describe the internal pH distributions. The cellular pH distributional response to external stress such as heat has not previously been determined. In this study, the intracellular pH (pHi) and the s.d.(pHint) of Saccharomyces cerevisiae cells exposed to supralethal temperatures were measured using...

  17. "Don't know" responses to risk perception measures: implications for underserved populations.

    Science.gov (United States)

    Waters, Erika A; Hay, Jennifer L; Orom, Heather; Kiviniemi, Marc T; Drake, Bettina F

    2013-02-01

    Risk perceptions are legitimate targets for behavioral interventions because they can motivate medical decisions and health behaviors. However, some survey respondents may not know (or may not indicate) their risk perceptions. The scope of "don't know" (DK) responding is unknown. Examine the prevalence and correlates of responding DK to items assessing perceived risk of colorectal cancer. Two nationally representative, population-based, cross-sectional surveys (2005 National Health Interview Survey [NHIS]; 2005 Health Information National Trends Survey [HINTS]), and one primary care clinic-based survey comprised of individuals from low-income communities. Analyses included 31,202 (NHIS), 1,937 (HINTS), and 769 (clinic) individuals. Five items assessed perceived risk of colorectal cancer. Four of the items differed in format and/or response scale: comparative risk (NHIS, HINTS); absolute risk (HINTS, clinic), and "likelihood" and "chance" response scales (clinic). Only the clinic-based survey included an explicit DK response option. "Don't know" responding was 6.9% (NHIS), 7.5% (HINTS-comparative), and 8.7% (HINTS-absolute). "Don't know" responding was 49.1% and 69.3% for the "chance" and "likely" response options (clinic). Correlates of DK responding were characteristics generally associated with disparities (e.g., low education), but the pattern of results varied among samples, question formats, and response scales. The surveys were developed independently and employed different methodologies and items. Consequently, the results were not directly comparable. There may be multiple explanations for differences in the magnitude and characteristics of DK responding. "Don't know" responding is more prevalent in populations affected by health disparities. Either not assessing or not analyzing DK responses could further disenfranchise these populations and negatively affect the validity of research and the efficacy of interventions seeking to eliminate health disparities.

  18. Light weakly interacting massive particles

    Science.gov (United States)

    Gelmini, Graciela B.

    2017-08-01

    Light weakly interacting massive particles (WIMPs) are dark matter particle candidates with weak scale interaction with the known particles, and mass in the GeV to tens of GeV range. Hints of light WIMPs have appeared in several dark matter searches in the last decade. The unprecedented possible coincidence into tantalizingly close regions of mass and cross section of four separate direct detection experimental hints and a potential indirect detection signal in gamma rays from the galactic center, aroused considerable interest in our field. Even if these hints did not so far result in a discovery, they have had a significant impact in our field. Here we review the evidence for and against light WIMPs as dark matter candidates and discuss future relevant experiments and observations.

  19. Food Safety and Quality Control: Hints from Proteomics

    Directory of Open Access Journals (Sweden)

    Angelo D'Alessandro

    2012-01-01

    Full Text Available Over the last decade, proteomics has been successfully applied to the study of quality control in production processes of food (including meat, wine and beer, transgenic plants and milk and food safety (screening for food-derived pathogens. Indeed, food quality and safety and their influence on the health of end consumers have growingly become a founding principle in the international agenda of health organizations. The application of proteomics in food science was at first characterized by exploratory analyses of food of various origin (bovine, swine, chicken or lamb meat, but also transgenic food such as genetically modified maize, for example and beverages (beer, wine, in parallel to the genomic and transcriptomic approaches seeking determination of quantitative trait loci. In the last few years, technical improvements such as microbial biotyping strategies have growingly allowed proteomicists to address the safety issue as well. The newly introduced technical improvements (instrumentation characterized by higher sensitivity such as mass spectrometers have paved the way for the individuation of food-contaminating pathogens in a fast and efficient workflow which is mandatory in industrial food production chains.

  20. An Impending geomagnetic transition? Hints from the past.

    Directory of Open Access Journals (Sweden)

    Carlo eLAJ

    2015-10-01

    Full Text Available The rapid decrease of the geomagnetic field intensity in the last centuries has led to speculations that an attempt to a reversal or an excursion might be under way. Here we investigate this hypothesis by examining past records of geomagnetic field intensity obtained from sedimentary cores and from the study of cosmogenic nuclides. The selected records describe geomagnetic changes with an unprecedented temporal resolution between 20 and 75 kyr B.P. We find that some aspects of the present-day geomagnetic field have some similarities with those documented for the Laschamp excursion 41 kyr ago. Under the assumption that the dynamo processes for an eventual future reversal or excursion would be similar to those of the Laschamp excursion, we tentatively suggest that, whilst irreversible processes that will drive the geodynamo into a polarity change may have already started, a reversal or an excursion should not be expected before 500 to 1000 years.

  1. An impending geomagnetic transition? Hints from the past

    OpenAIRE

    Laj, Carlo; Kissel, Catherine

    2015-01-01

    The rapid decrease of the geomagnetic field intensity in the last centuries has led to speculations that an attempt to a reversal or an excursion might be under way. Here we investigate this hypothesis by examining past records of geomagnetic field intensity obtained from sedimentary cores and from the study of cosmogenic nuclides. The selected records describe geomagnetic changes with an unprecedented temporal resolution between 20 and 75 kyr B.P. We find that some aspects of the present-day...

  2. Brotze väljaande filoloogilisi probleeme / Mati Hint

    Index Scriptorium Estoniae

    Hint, Mati

    2007-01-01

    Rets. rmt. : Johann Christoph Brotze. Estonica. Koostanud / Herausgegeben von Ants Hein, Ivar Leimus, Raimo Pullat, Ants Viires. Projektijuht ja vastutav toimetaja : Raimo Pullat. tõlge eesti keelde: Tõnis Liibek, Ivar Leimus, tõlge saksa keelde: Aigi Heero, Ene Rõngelep. Kujundus: Andres Tali. Tallinn : Estopol OÜ, 2006. XXXVI, 619 lk. Teoses esinevaid keele- ja kohanimeprobleeme

  3. Ageing collider throws up hint or dark matter

    CERN Multimedia

    Ananthaswamy, Anil

    2008-01-01

    "Never mind the Large Hadron Collider at CERN, its ageing predecessor may have discovered a new and unexpected kind of particle. The announcement last week from the Tevatron particle accelerator at Fermilab in Batavai, Illinois, provided some excitement amid the frustration of ongoing repairs to the LHC."

  4. New planet hints at life in the stars

    CERN Multimedia

    Dalton, A W

    2002-01-01

    Astronomers have detected a distant planet 100 light years from Earth, circling Tau1 Gruis, its star, in the constellation of Grus (the crane). The planet, similar in appearance to Jupiter, is three times as far away from its star as the Earth is from the Sun and takes four years to revolve around the star, in a roughly circular orbit. Scientists believe this type of planetary orbit is the most promising for finding worlds that contain life (1 page).

  5. Generation of Tutorial Dialogues: Discourse Strategies for Active Learning

    Science.gov (United States)

    1998-05-29

    AND SUBTITLE Generation of Tutorial Dialogues: Discourse Strategies for active Learning AUTHORS Dr. Martha Evens 7. PERFORMING ORGANI2ATION NAME...time the student starts in on a new topic. Michael and Rovick constantly attempt to promote active learning . They regularly use hints and only resort...Controlling active learning : How tutors decide when to generate hints. Proceedings of FLAIRS 󈨣. Melbourne Beach, FL. 157-161. Hume, G., Michael

  6. Reseach blog:

    DEFF Research Database (Denmark)

    Lieberoth, Andreas

    2011-01-01

    Ongoing research blog discussing Andreas' research in the psychology of applied games, as well as general musings on cognitive neuroscience, game-design, and more. Also contains hints and guides for students on writing psychology research-papers.......Ongoing research blog discussing Andreas' research in the psychology of applied games, as well as general musings on cognitive neuroscience, game-design, and more. Also contains hints and guides for students on writing psychology research-papers....

  7. Structure determination of the neutral exopolysaccharide produced by Lactobacillus delbrueckii subsp. bulgaricus OLL1073R-1.

    Science.gov (United States)

    Van Calsteren, Marie-Rose; Gagnon, Fleur; Nishimura, Junko; Makino, Seiya

    2015-09-02

    The neutral exopolysaccharide (NPS) of Lactobacillus delbrueckii subsp. bulgaricus strain OLL1073R-1 was purified and characterized. The molecular mass was 5.0×10(6) g/mol. Sugar and absolute configuration analyses gave the following composition: d-Glc, 1; d-Gal, 1.5. The NPS was also submitted to periodate oxidation followed by borohydride reduction and Smith degradation. Sugar and methylation analyses, (1)H and (13)C nuclear magnetic resonance, and mass spectrometry of the NPS or of its specifically modified products allowed determining the repeating unit sequence: {2)Glc(α1-3)Glc(β1-3)[Gal(β1-4)]Gal(β1-4)Gal(α1-}n. The structure is compared to that of exopolysaccharides produced by other Lactobacillus bulgaricus strains. Copyright © 2015. Published by Elsevier Ltd.

  8. Performance and optimization of support vector machines in high-energy physics classification problems

    Energy Technology Data Exchange (ETDEWEB)

    Sahin, Mehmet Oezguer; Kruecker, Dirk; Melzer-Pellmann, Isabell [DESY, Hamburg (Germany)

    2016-07-01

    In this talk, the use of Support Vector Machines (SVM) is promoted for new-physics searches in high-energy physics. We developed an interface, called SVM HEP Interface (SVM-HINT), for a popular SVM library, LibSVM, and introduced a statistical-significance based hyper-parameter optimization algorithm for the new-physics searches. As example case study, a search for Supersymmetry at the Large Hadron Collider is given to demonstrate the capabilities of SVM using SVM-HINT.

  9. Translations on USSR Military Affairs, Number 1328.

    Science.gov (United States)

    1978-02-02

    of his age. This news came as no surprise to Mikhail Vasil’yevich, and he reported to the commander his readiness immediately to begin the transfer...for this period, in which regard he dropped a hint to the commander. 103 Major Labushev did not take the hint. Convinced that there was no mutual...District. It was directed thence to the garrison judge advocate, who sent Mikhail Vasil’yevich an encouraging letter. It declared that his unit

  10. Üks vormiõpetus (I) : Vaimumõõgad / Henn Saari

    Index Scriptorium Estoniae

    Saari, Henn, 1924-1999

    1998-01-01

    Diskussioonist eesti nüüdiskeele võrmiõpetuse ning selle eelduseks oleva fooniasüsteemi üle uut õigekeelsussõnaraamatut ette valmistades. Vt. ka: Ehala, Martin. Eesti morfoloogia olemus // Keel ja Kirjandus, 1997, nr. 6 ; Hint, Mati. Eesti foneetika möödunud hiilgus ja möödumata viletsus // Keel ja Kirjandus, 1997, nr. 2 ; Ross, Kristiina. Eesti morfo(fono)loogia põnevamad probleemid : EKG contra Mati Hint // Keel ja Kirjandus, 1997, nr. 5

  11. Towards high-density matter with relativistic heavy-ion collisions

    International Nuclear Information System (INIS)

    Nagamiya, Shoji.

    1990-04-01

    Recent progress in nucleus-nucleus collisions at BNL and CERN suggests a hint that the formation of high-density nuclear matter could be possible with relativistic heavy-ion beams. What is the maximum density that can be achieved by heavy-ion collisions? Are there data which show evidence or hints on the formation of high density matter? Why is the research of high-density interesting? How about the future possibilities on this subject? These points are discussed. (author)

  12. From the standard model to dark matter

    International Nuclear Information System (INIS)

    Wilczek, F.

    1995-01-01

    The standard model of particle physics is marvelously successful. However, it is obviously not a complete or final theory. I shall argue here that the structure of the standard model gives some quite concrete, compelling hints regarding what lies beyond. Taking these hints seriously, one is led to predict the existence of new types of very weakly interacting matter, stable on cosmological time scales and produced with cosmologically interesting densities--that is, ''dark matter''. copyright 1995 American Institute of Physics

  13. Cool WISPs for stellar cooling excesses

    Energy Technology Data Exchange (ETDEWEB)

    Giannotti, Maurizio [Physical Sciences, Barry University, 11300 NE 2nd Avenue, Miami Shores, FL 33161 (United States); Irastorza, Igor; Redondo, Javier [Departamento de Física Teórica, Universidad de Zaragoza, Pedro Cerbuna 12, E-50009, Zaragoza, España (Spain); Ringwald, Andreas, E-mail: mgiannotti@barry.edu, E-mail: igor.irastorza@cern.ch, E-mail: jredondo@unizar.es, E-mail: andreas.ringwald@desy.de [Theory group, Deutsches Elektronen-Synchrotron DESY, Notkestraße 85, D-22607 Hamburg (Germany)

    2016-05-01

    Several stellar systems (white dwarfs, red giants, horizontal branch stars and possibly the neutron star in the supernova remnant Cassiopeia A) show a mild preference for a non-standard cooling mechanism when compared with theoretical models. This exotic cooling could be provided by Weakly Interacting Slim Particles (WISPs), produced in the hot cores and abandoning the star unimpeded, contributing directly to the energy loss. Taken individually, these excesses do not show a strong statistical weight. However, if one mechanism could consistently explain several of them, the hint could be significant. We analyze the hints in terms of neutrino anomalous magnetic moments, minicharged particles, hidden photons and axion-like particles (ALPs). Among them, the ALP or a massless HP represent the best solution. Interestingly, the hinted ALP parameter space is accessible to the next generation proposed ALP searches, such as ALPS II and IAXO and the massless HP requires a multi TeV energy scale of new physics that might be accessible at the LHC.

  14. Cool WISPs for stellar cooling excesses

    International Nuclear Information System (INIS)

    Giannotti, Maurizio; Irastorza, Igor; Redondo, Javier; Ringwald, Andreas

    2016-01-01

    Several stellar systems (white dwarfs, red giants, horizontal branch stars and possibly the neutron star in the supernova remnant Cassiopeia A) show a mild preference for a non-standard cooling mechanism when compared with theoretical models. This exotic cooling could be provided by Weakly Interacting Slim Particles (WISPs), produced in the hot cores and abandoning the star unimpeded, contributing directly to the energy loss. Taken individually, these excesses do not show a strong statistical weight. However, if one mechanism could consistently explain several of them, the hint could be significant. We analyze the hints in terms of neutrino anomalous magnetic moments, minicharged particles, hidden photons and axion-like particles (ALPs). Among them, the ALP or a massless HP represent the best solution. Interestingly, the hinted ALP parameter space is accessible to the next generation proposed ALP searches, such as ALPS II and IAXO and the massless HP requires a multi TeV energy scale of new physics that might be accessible at the LHC.

  15. A "g" beyond "Homo Sapiens"? Some Hints and Suggestions

    Science.gov (United States)

    Lee, James J.

    2007-01-01

    This article proposes that a complete account of cognitive evolution may have to accommodate a domain-general source of variance in mental abilities accounting for differences among primate taxa. Deaner, van Schaik, and Johnson [Deaner, R.O., van Schaik, C.P. and Johnson, V.E. (2006). Do some taxa have better domain-general cognition than others?…

  16. Hints for electric-field compensation in multicell resonant structures

    Energy Technology Data Exchange (ETDEWEB)

    Fernandes, P; Parodi, R

    1981-03-31

    We propose a lumped-parameter equivalent circuit for a TM/sub 01/ multicell standing wave accelerating structure with full end cells. By the suggested model we can predict the amount of end cell frequency compensation needed to achieve field flatness in the highest mode of the structure.

  17. Sünnitades "Ema ja tütart" / Anna Hints

    Index Scriptorium Estoniae

    Hints, Anna, 1982-

    2010-01-01

    Tartu sünnitusmajale Toomemäel, naise eluringile ja põlvkondade järjepidevusele pühendatud "Ema ja tütar" kui koha, heli, foto ja rituaalse tegevuse koostoimel sündinud autori tajuvõrgustikku dekodeeriv pärimusliku ja isikliku taustaga kunstitöö

  18. Short views and hints on information, knowledge and scenarios

    DEFF Research Database (Denmark)

    Kristiansson, Michael

    2011-01-01

    This article discusses information and knowledge in relation to scenario planning (van der Heijden) and considers the type of information that is relied on/included as well as the nature of knowledge produced by the scenario planning sequence. In addition, the chief tools and processes drawn upon...

  19. Mari Koger : seina sisse ehitatud akvaariumiga poissmehekodu / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    80-ruutmeetrine poissmehekorter Viimsi uues elamus. Elutoa ja vannitoa vahelises seinas paikneb kahelt poolt vaadeldav akvaarium. Magamistoa üks seintest on ehitatud vanadest tellistest. Sisearhitekt Mari Koger, tema kommentaarid. Ill.: plaan, 9 värv. vaadet

  20. Tiina Mang : vanalinna korter muutus visuaalselt suuremaks / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    74-ruutmeetrine vanalinna korter, mõeldud kahele inimesele, kellest üks töötab kodus. Enamik mööblist on valmistatud eritellimusel. Sisearhitekt Tiina Mang, tema kommentaarid. Ill.: plaan, 3 värv. vaadet

  1. 200 more puzzling physics problems with hints and solutions

    CERN Document Server

    Gnädig, Péter; Vigh, Máté

    2016-01-01

    Like its predecessor, 200 Puzzling Physics Problems, this book is aimed at strengthening students' grasp of the laws of physics by applying them to situations that are practical, and to problems that yield more easily to intuitive insight than to brute-force methods and complex mathematics. The problems are chosen almost exclusively from classical, non-quantum physics, but are no easier for that. They are intriguingly posed in accessible non-technical language, and require readers to select an appropriate analysis framework and decide which branches of physics are involved. The general level of sophistication needed is that of the exceptional school student, the good undergraduate, or the competent graduate student; some physics professors may find some of the more difficult questions challenging. By contrast, the mathematical demands are relatively minimal, and seldom go beyond elementary calculus. This further book of physics problems is not only instructive and challenging, but also enjoyable.

  2. Aet Piel : oluline sisekujunduselement on viltune sein / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Poolkaares ehitatud korterelamus on Aet Pieli kujundatud korteris üks sein viltu. Esmapilgul häirivana mõjunud sein sai oluliseks sisekujunduselemendiks. Eritellimusel valmistatud mööbel on tammepuidust. A. Pieli kommentaarid. Ill.: plaan enne ja nüüd, 9 värv. vaadet

  3. Remembering Multiple Passwords by Way of Minimal-Feedback Hints

    DEFF Research Database (Denmark)

    Hertzum, Morten

    2004-01-01

    Passwords are a prominent mechanism for user authentication but entail a conflict between ease of use and security in that passwords must be both easy to remember for the password holder and difficult to guess for everybody else. To support users in remembering their passwords minimal-feedback...

  4. Using peer instruction with hints in introductory business statistics

    NARCIS (Netherlands)

    Ding, Ning; Xu, Xiaoyan

    2014-01-01

    Abstract:Purpose – Peer instruction has been widely adopted as an instructional method in higher education. However, due to students' different preconceptions, the authors argued that peer instruction is not a panacea in international business education when students' prior knowledge extensively

  5. Taso Mähar : avatud vannitoaga vanalinna korter / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Modernne korter (220 m2). Sisearhitekt Taso Mähar, tema kommentaarid. Kogu korteri ulatuses on sisekujundusmaterjalidena kasutatud väärispuitu, metalli, marmorit ja klaasi. T. Mähari projekteeritud on trepp ja piirded, kamin, baarilett ja õhukesed alumiiniumraamidel mattklaasidega uksed. Ill.: I ja II korruse plaan, 8 värv. vaadet

  6. "To Improve upon Hints of Things": Illustrating Isaac Newton.

    Science.gov (United States)

    Schilt, Cornelis J

    2016-01-01

    When Isaac Newton died in 1727 he left a rich legacy in terms of draft manuscripts, encompassing a variety of topics: natural philosophy, mathematics, alchemy, theology, and chronology, as well as papers relating to his career at the Mint. One thing that immediately strikes us is the textuality of Newton's legacy: images are sparse. Regarding his scholarly endeavours we witness the same practice. Newton's extensive drafts on theology and chronology do not contain a single illustration or map. Today we have all of Newton's draft manuscripts as witnesses of his working methods, as well as access to a significant number of books from his own library. Drawing parallels between Newton's reading practices and his natural philosophical and scholarly work, this paper seeks to understand Newton's recondite writing and publishing politics.

  7. New physics hints in B decays and collider outlook

    Indian Academy of Sciences (India)

    Less noticed is the difference in direct CPV (DCPV) asymmetries in B0 ... Our working picture is that squarks are relatively degenerate at some ... We stress that the new (and unique!) ..... [1] See http://mlm.home.cern.ch/mlm/FlavLHC.html.

  8. DEMYSTIFYING QUANTUM MECHANICS: Will there be hints from LHC?

    CERN Multimedia

    CERN. Geneva

    2007-01-01

    All modern theories for particles, forces and even space-time itself, use the framework provided by quantum mechanics. The Standard Model is a quantized field theory. Even superstring theory is based on quantum mechanics. There is something odd about quantum mechanics: it brilliantly allows us to predict the outcome of experiments, yet it gives confusing statements about what really is going on inside particles and fields. Suppose we would be asking for a theory that allows us to describe what actually happens in less ambiguous terms, without destroying the magnificent successes of quantum mechanics, would this help us to answer some of the great mysteries of theoretical elementary particle physics?Organiser(s): L. Alvarez-Gaume / PH-THNote: * Tea & coffee will be served at 16:00.

  9. MHD equilibrium of heliotron J plasmas

    International Nuclear Information System (INIS)

    Suzuki, Yasuhiro; Nakamura, Yuji; Kondo, Katsumi; Nakajima, Noriyoshi; Hayashi, Takaya

    2004-01-01

    MHD equilibria of Heliotron J plasma are investigated by using HINT code. By assuming some profiles of the current density, effects of the net toroidal currents on the magnetohydrodynamics (MHD) equilibrium are investigated. If the rotational transform can be controlled by the currents, the generation of good flux surfaces is expected. In order to study equilibria with self-consistent bootstrap current, the boozer coordinates are constructed by converged HINT equilibrium as a preliminary study. Obtained spectra are compared with ones of VMEC code and both results are consistent. (author)

  10. Energetics of the protein-DNA-water interaction

    Directory of Open Access Journals (Sweden)

    Marabotti Anna

    2007-01-01

    Full Text Available Abstract Background To understand the energetics of the interaction between protein and DNA we analyzed 39 crystallographically characterized complexes with the HINT (Hydropathic INTeractions computational model. HINT is an empirical free energy force field based on solvent partitioning of small molecules between water and 1-octanol. Our previous studies on protein-ligand complexes demonstrated that free energy predictions were significantly improved by taking into account the energetic contribution of water molecules that form at least one hydrogen bond with each interacting species. Results An initial correlation between the calculated HINT scores and the experimentally determined binding free energies in the protein-DNA system exhibited a relatively poor r2 of 0.21 and standard error of ± 1.71 kcal mol-1. However, the inclusion of 261 waters that bridge protein and DNA improved the HINT score-free energy correlation to an r2 of 0.56 and standard error of ± 1.28 kcal mol-1. Analysis of the water role and energy contributions indicate that 46% of the bridging waters act as linkers between amino acids and nucleotide bases at the protein-DNA interface, while the remaining 54% are largely involved in screening unfavorable electrostatic contacts. Conclusion This study quantifies the key energetic role of bridging waters in protein-DNA associations. In addition, the relevant role of hydrophobic interactions and entropy in driving protein-DNA association is indicated by analyses of interaction character showing that, together, the favorable polar and unfavorable polar/hydrophobic-polar interactions (i.e., desolvation mostly cancel.

  11. Joint statement by the chairmen of the Standing Committee on Reactors and the Reactor Safety Commission on safety-related documents drawn up under the Franco-German Commission on Safety Questions for Nuclear Installations (DFK). August 29, 1986

    International Nuclear Information System (INIS)

    1986-01-01

    The report contains: 1. The present situation regarding hints and recommendations in the safety declaration by the TUEV Baden on the subject of Cattenom nuclear power station in June 1982. 2. The present situation regarding hints and recommendations in the declaration by the TUEV Rhineland in February 1982 on the subject of radiological aspects and features of the Cattenom site for the nuclear power plant. 3. Answers to press allegations about the safety of Cattenom NPP: scram system, safety cooling system, heat sink for after-heat removal, emergency power supplies, load-follow operation, air crashes, susceptibility to failures. (orig./HP) [de

  12. Using big-data to validate theories of rehabilitation in aphasia

    Directory of Open Access Journals (Sweden)

    Swathi Kiran

    2015-05-01

    Full Text Available Introduction. While the evidence for efficacy of rehabilitation of language disorders is fairly robust and conclusive (Allen, et al., 2012; Brady, et al., 2012; Kelly, Brady, & Enderby, 2010; Cherney, et al., 2008, a major limitation identified by these reviews is that the sample size of patients in each of the interventions have been modest (5-20 patients. As technology moves our field forward, we can now collect and analyze larger sets of data to validate theories of rehabilitation. As a first step, we report data from a recently completed study examining the effectiveness of software platform (Constant Therapy to deliver, monitor and analyze treatment for individuals with aphasia (Des Roches et al., 2015. Methods. Fifty one individuals with language and cognitive deficits were administered standardized tests (Western Aphasia Battery, Boston Naming Test, Pyramids and Palm Trees, and Cognitive Linguistic Quick Test prior to initiation and following completion of therapy. Forty-two experimental patients used the iPad-based therapy once a week with the clinician and up to six days a week for home practice. Nine control patients practiced therapy on the iPad once per week with the clinician only. Thirty-eight therapy tasks were divided into language and cognitive activities that were developed (Des Roches et al., 2015, 28 of these tasks included buttons that revealed a hint to assist the patient answer the item. The assigned therapy tasks were tailored to that individual’s language and cognitive impairment profile based on an initial baseline assessment. Each task was practiced until accuracy on task reached 100% on multiple occasions at which point that task was replaced with the task at the next level of difficulty. The 51 patients each completed a 10 week program leading to total of 3327 therapy sessions across patients. Analysis and Results: Mixed regression models showed that both the experimental and control groups improved but

  13. Learning To Learn: 15 Vocabulary Acquisition Activities. Tips and Hints.

    Science.gov (United States)

    Holden, William R.

    1999-01-01

    This article describes a variety of ways learners can help themselves remember new words, choosing the ones that best suit their learning styles. It is asserted that repeated exposure to new lexical items using a variety of means is the most consistent predictor of retention. The use of verbal, visual, tactile, textual, kinesthetic, and sonic…

  14. HINT for Squint: A Computer Reliant Diagnostic Aid for Strabismus

    OpenAIRE

    Gieszl, Louis R.; Morris, Jacqueline; Guyton, David L.

    1983-01-01

    This paper provides an outline of methods used for the implementation of a computer reliant diagnostic aid in the medical specialty of Ophthalmology. Some problems have been associated with many previous diagnostic models. A careful review indicates that the most serious problems were:

  15. IceCube events and decaying dark matter: hints and constraints

    Science.gov (United States)

    Esmaili, Arman; Kang, Sin Kyu; Dario Serpico, Pasquale

    2014-12-01

    In the light of the new IceCube data on the (yet unidentified) astrophysical neutrino flux in the PeV and sub-PeV range, we present an update on the status of decaying dark matter interpretation of the events. In particular, we develop further the angular distribution analysis and discuss the perspectives for diagnostics. By performing various statistical tests (maximum likelihood, Kolmogorov-Smirnov and Anderson-Darling tests) we conclude that currently the data show a mild preference (below the two sigma level) for the angular distribution expected from dark matter decay vs. the isotropic distribution foreseen for a conventional astrophysical flux of extragalactic origin. Also, we briefly develop some general considerations on heavy dark matter model building and on the compatibility of the expected energy spectrum of decay products with the IceCube data, as well as with existing bounds from gamma-rays. Alternatively, assuming that the IceCube data originate from conventional astrophysical sources, we derive bounds on both decaying and annihilating dark matter for various final states. The lower limits on heavy dark matter lifetime improve by up to an order of magnitude with respect to existing constraints, definitively making these events—even if astrophysical in origin—an important tool for astroparticle physics studies.

  16. IceCube events and decaying dark matter: hints and constraints

    International Nuclear Information System (INIS)

    Esmaili, Arman; Kang, Sin Kyu; Serpico, Pasquale Dario

    2014-01-01

    In the light of the new IceCube data on the (yet unidentified) astrophysical neutrino flux in the PeV and sub-PeV range, we present an update on the status of decaying dark matter interpretation of the events. In particular, we develop further the angular distribution analysis and discuss the perspectives for diagnostics. By performing various statistical tests (maximum likelihood, Kolmogorov-Smirnov and Anderson-Darling tests) we conclude that currently the data show a mild preference (below the two sigma level) for the angular distribution expected from dark matter decay vs. the isotropic distribution foreseen for a conventional astrophysical flux of extragalactic origin. Also, we briefly develop some general considerations on heavy dark matter model building and on the compatibility of the expected energy spectrum of decay products with the IceCube data, as well as with existing bounds from gamma-rays. Alternatively, assuming that the IceCube data originate from conventional astrophysical sources, we derive bounds on both decaying and annihilating dark matter for various final states. The lower limits on heavy dark matter lifetime improve by up to an order of magnitude with respect to existing constraints, definitively making these events—even if astrophysical in origin—an important tool for astroparticle physics studies

  17. Taso Mähar : maali ümber ehitatud maja / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    220-ruutmeetrise ühekorde eramu sisekujundus. Arhitekt Emil Urbel. Sisearhitekt Taso Mähar, tema kommentaarid. Köögimööbel on T. Mähari projekteeritud. Elutoas mööblifirma T&T Mang pehme mööbel, seinal Lemming Nageli maal "Punane joon all - Burn Out". Ill.: plaan, 17 värv. vaadet

  18. What Caused the Recession of 2008? Hints from Labor Productivity

    OpenAIRE

    Casey Mulligan

    2009-01-01

    A labor market tautology says that any change in labor usage can be decomposed into a movement along a marginal productivity schedule and a shift of the schedule. I calculate this decomposition for the recession of 2008, assuming an aggregate Cobb-Douglas marginal productivity schedule, and find that all of the decline in employment and hours since December 2007 is a movement along the schedule. This finding suggests that a reduction in labor supply and/or an increase in labor market distorti...

  19. Phenomenological Hints from a Class of String Motivated Model Constructions

    Directory of Open Access Journals (Sweden)

    Hans Peter Nilles

    2015-01-01

    Full Text Available We use string theory constructions towards the generalisation of the supersymmetric standard model of strong and electroweak interactions. Properties of the models depend crucially on the location of fields in extradimensional compact space. This allows us to extract some generic lessons for the phenomenological properties of the low energy effective action. Within this scheme we present a compelling model based on local grand unification and mirage mediation of supersymmetry breakdown. We analyse the properties of the specific model towards its possible tests at the LHC and the complementarity to direct dark matter searches.

  20. Building Models to Predict Hint-or-Attempt Actions of Students

    Science.gov (United States)

    Castro, Francisco Enrique Vicente; Adjei, Seth; Colombo, Tyler; Heffernan, Neil

    2015-01-01

    A great deal of research in educational data mining is geared towards predicting student performance. Bayesian Knowledge Tracing, Performance Factors Analysis, and the different variations of these have been introduced and have had some success at predicting student knowledge. It is worth noting, however, that very little has been done to…

  1. Riemannian geometry of Hamiltonian chaos: hints for a general theory.

    Science.gov (United States)

    Cerruti-Sola, Monica; Ciraolo, Guido; Franzosi, Roberto; Pettini, Marco

    2008-10-01

    We aim at assessing the validity limits of some simplifying hypotheses that, within a Riemmannian geometric framework, have provided an explanation of the origin of Hamiltonian chaos and have made it possible to develop a method of analytically computing the largest Lyapunov exponent of Hamiltonian systems with many degrees of freedom. Therefore, a numerical hypotheses testing has been performed for the Fermi-Pasta-Ulam beta model and for a chain of coupled rotators. These models, for which analytic computations of the largest Lyapunov exponents have been carried out in the mentioned Riemannian geometric framework, appear as paradigmatic examples to unveil the reason why the main hypothesis of quasi-isotropy of the mechanical manifolds sometimes breaks down. The breakdown is expected whenever the topology of the mechanical manifolds is nontrivial. This is an important step forward in view of developing a geometric theory of Hamiltonian chaos of general validity.

  2. Kaire Kemp-Tishler : harmoonia moodsa ja vana vahel / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Eramu sisekujundus. Sisearhitekt Kaire Kemp-Tishler, tema kommentaarid. Arhitekt Vahur Sova. Kamina sepised tegi Heigo Jelle. Trepihallis Tiit Pääsukese maal "Orasnzh". Ill.: I ja II korruse plaan, 14 värv. vaadet

  3. Kaire Kemp-Tishler: "Igatsen luua midagi kole-ilusat" / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Kaire Kemp-Tishler (sünd. 1964) kodu sisekujunduse projekteerimisest, tasakaalust sisearhitektuuris, oma kodust. Kaire Kemp-Tishlerist, tema tehtud tööde loetelu. 1998. aastast teeb K. Kemp-Tishler koostööd Ea Andlaga, kellega koos asutas 2001. a. OÜ sisearhitektuuribüroo ArtAku. Ill.: K. Kemp-Tishleri värv. portree

  4. Hints about Dark, Light-Bending Matter in the Distant Universe

    Science.gov (United States)

    1997-07-01

    New infrared observations of a gravitational lens About 20 cases of gravitationally lensed (GL) quasars are known. This special physical effect, also known as a cosmic mirage, occurs when the rays of light of a distant quasar on their way to us pass near a massive object, for instance a galaxy. As a result, two or more images of the same quasar will be seen near each other. This phenomenon is described in more detail in the Appendix. A new study by a group of three European astronomers, headed by Frederic Courbin ( Institut d'Astrophysique, Universite de Liege, Belgium, and Observatoire de Paris-Meudon, France) [1], has led to the discovery of the object responsible for the double images of a remote quasar in the gravitational lens HE 1104-1805 . The investigation is based on infrared observations at the ESO La Silla Observatory in Chile and the `lensing system' turns out to be a distant, massive galaxy. Nevertheless, the geometry of the object is unusual and an additional gravitational lens of `dark' (invisible) matter may possibly be involved. This gravitational lens is also particularly well suited for future cosmological studies that aim at the determination of the Hubble constant and the expansion rate of the Universe. A new and detailed study of gravitational lenses It is rare among the relatively few, confirmed cases of gravitational lensing in the distant Universe, that the distribution of matter in the lensing system is well known. However, it is exactly this information that is needed to derive cosmological parameters by means of photometric monitoring of the brightness of the individual images in a gravitational lens [2]. The three astronomers have therefore undertaken a detailed study of some previously known gravitational lenses (or good candidate objects) with the primary aim to detect and map the associated lensing matter (refered to as the gravitational deflector or lensing object ). This is observationally quite difficult and time-consuming since the huge masses responsible for the gravitational bending of light are almost always located at very large distances from us. Thus they are quite faint and can only be observed with large telescopes and state-of-the-art equipment. Moreover, the faint images of lensing objects are located between the much brighter quasar images they lens. This makes the discovery of a lensing object and the recording of its image a most challenging task. The advantage of infrared observations The image of a remote galaxy is usually very faint at visible wavelengths, but it is brighter in the infra-red part of the spectrum. This is because the wavelength of maximum intensity in the spectrum of a rapidly receding, distant galaxy (a composite of the spectra of the stars of which it consists) is redshifted from the visual into the infrared region of the spectrum. For instance, galaxies with redshifts around z = 1 [3] are best observed in the J -band near the near-infrared wavelength of 1.25 microns (about twice that of red light), while the images of galaxies with even higher redshifts and velocities are better recorded in the 2.2 micron K -band. The present search for gravitational deflectors is therefore conducted in the infrared spectral region, using the ESO/MPI 2.2-m telescope and the IR detector IRAC 2b . Such a survey has the further advantage of revealing, if present, additional lensed images of the quasars, that may be heavily obscured by intervening dust, for example by the dust contained in the lensing galaxy. A new and powerful image combination/deconvolution algorithm These investigations have always been difficult because of the small angular separations in such lensed objects, of the order of one arcsecond, or even less in many cases. This corresponds to the image-smearing (seeing) effects introduced by atmospheric turbulence under common ground-based observing conditions. Detailed observations of such objects are therefore normally best made from space-based observatories, like the Hubble Space Telescope (HST). However, an alternative method of obtaining high-resolution images is to combine numerous exposures of the same object in an optimised way; this allows to `eliminate' most of the image degradation caused by atmospheric effects. New and powerful software for this procedure has recently been developed at the Astrophysical Institute in Liege, cf. http://vela.astro.ulg.ac.be/imaproc. The new algorithm allows to treat (`deconvolve') simultaneously a large number of exposures - especially in the infrared - and yields high-resolution, combined images of the celestial objects on which precise brightness and positional measurements can be performed. Detection of the lensing galaxy in HE 1104-1805 During the present programme, the astronomers recently observed HE 1104-1805 , a gravitational lens with a doubly imaged quasar with a redshift of z = 2.316 that was discovered in 1993 at the La Silla Observatory. Observations in 1995, made in the I -waveband (0.9 micron) under poor seeing conditions, showed a very faint feature between the quasar images but the observations did not allow to ascertain the nature of this object. Caption to ESO PR Photo 21/97 [JPEG, 55k] New infrared images were obtained during the night of April 14-15, 1997. They were then processed with the new software and the resulting, detailed images with high-angular resolution, 0.27 arcsec, now show very clearly the lensing object, a remote, elliptical galaxy, between the quasar images. The image displayed in ESO Press Photo 21/97 was obtained in the near-infrared J-band, where the lensing galaxy in HE 1104-1805 is quite faint, but still well visible and measurable after `deconvolution'. The observed, infrared colour, i.e. the difference in brightness of its image in the J- and K-bands (the (J-K) index ), is compatible with that of a high-redshift elliptical galaxy, at a distance corresponding to a redshift somewhere between z = 1 and z = 1.8. The brightest of the two quasar images (`A'; the upper one in ESO PR Photo 21/97) shows absorption lines in its spectrum which have been redshifted at z = 1.66. Since the lensing galaxy is situated at a small angular distance from this component, it is quite likely that these spectral lines are produced by this galaxy. Thus, the gravitational deflector in HE 1104-1805 is most probably an elliptical galaxy at redshift z = 1.66. This corresponds to a recession velocity of about 200,000 km/sec and a distance that, depending on the adopted Hubble relation, is of the order of 6,000 - 9,000 million light-years. Since this galaxy is comparatively bright in the infrared, this may be checked in the near future by taking an infrared spectrum, for example with the future IR instrument of the ESO New Technology Telescope, SOFI, cf. ESO Press Photo 17/97. Continued studies of HE 1104-1805 This gravitational lens is known to show brightness variations with time. It is therefore a good candidate for continued photometric monitoring which may possibly yield a new and independent determination of the Hubble constant [2], as this was recently done for another gravitational lens, PG 1115+080 [4]. If the lensing galaxy is actually located at redshift z = 1.66, then the time delay expected for brightness variations of the two lensed quasar images is of the order of 3 to 4 years, depending on the model. This should be easily measurable. A `Dark Lens' in HE 1104-1805? The observed geometry of HE 1104-1805 is somewhat surprising, since current lens models predict that the position of the deflector, as seen in the sky, is closer to the fainter quasar image than to the brighter one; here the contrary is the case. This would suggest that the distribution of the lensing matter is more complex than that of a single elliptical galaxy. In addition, the brightness of the lensing galaxy in the K-band is somewhat too high for a normal one. This may indicate the presence of a more massive object, for example a cluster of galaxies. This may not be the case, though, since the present, very deep observations would have allowed the detection of any normal cluster of galaxies between us and the quasar whose light is being split by the lens. An interesting question is therefore: do we `see' the effects of a lens of dark matter in HE 1104-1805? Only future observations, for instance with the ESO Very Large Telescope (VLT) , will tell. Where to find additional information More details about the image deconvolution techniques used for this investigation is available at the WWW pages of the Liege group. Information about another gravitational-lens related discovery by astronomers at the Institut d'Astrophysique in Liege have been reported in ESO Press Release 04/96 (9 February 1996). Notes: [1] The group consists of Frederic Courbin (Institut d'Astrophysique, Universite de Liege, Belgium, and Observatoire de Paris-Meudon, France) and Pierre Magain (Institut d'Astrophysique, Universite de Liege, Belgium) and Chris Lidman (ESO). [2] The careful observation of similar, but time-shifted brightness variations of the individual images of a quasar in a gravitational lens may sometimes lead to a determination of the distance to the lensing object (normally a distant galaxy). This is because the measured time delay of such variations (from some months to several years), from the known speed of light, will provide a direct indication of the difference in the length of the two light paths, expressed in kilometres. If moreover the overall distribution of the matter that causes the lensing effect is known (from observations of the shape of the lens) and thus the relative geometry of the lensing system and the light paths, it is then possible to estimate the absolute size of the system. When this is compared with its angular size (as seen in the sky on direct images), the true distance to the lensing object can be found. Dividing this distance with the measured recession velocity (along the line-of-sight), finally gives an independent value of the expansion rate of the Universe, the famous Hubble constant . [3] In astronomy, the redshift denotes the fraction by which the lines in the spectrum of an object are shifted towards longer wavelengths. The observed redshift of a distant galaxy or quasar gives a direct estimate of the apparent recession velocity as caused by the universal expansion. Since the expansion rate increases with the distance, the velocity is itself a function (the Hubble relation) of the distance to the object. A redshift of z = 1 corresponds to a recession velocity of 180,000 km/sec; z = 2 to 214,300 km/sec, z = 3 to 233,300 km/sec, and z = 4 to 245,500 km/sec; the non-proportionality is a relativistic effect. [4] Detailed information about PG 1115+080 may be found in the scientific papers by Schechter et al. (1997, ApJ, 475, L85) and Courbin et al. (1997, SISSA preprint astro-ph/9705093, A&A Letters, in press). Appendix: What is a gravitational lens? The physical principle behind a gravitational lens (also known as a cosmic mirage ) has been known since 1916 as a consequence of Einstein's General Relativity Theory. The gravitational field of a massive object curves the local geometry of the Universe, so light rays passing close to the object are also curved (in the same way as a `straight line' on the surface of the Earth is necessarily curved because of the curvature of the Earth's surface). This effect was first observed by astronomers in 1919 during a total solar eclipse. Accurate positional measurements of stars seen in the dark sky near the eclipsed Sun indicated an apparent displacement in the direction opposite to the Sun, about as much as predicted by the theory. The effect was obviously due to the gravitational attraction of the stellar photons when they passed near the Sun on their way to us. This was a direct confirmation of a new phenomenon and represented a milestone in physics. In the 1930's, astronomer Fritz Zwicky (1898 - 1974), of Swiss nationality and working at the Mount Wilson Observatory in California, realised that the same effect may also happen far out in space where galaxies and large galaxy clusters may be sufficiently compact and massive to bend the light from even more distant objects. However, it was only five decades later, in 1979, that his ideas were observationally confirmed when the first example of a cosmic mirage was discovered. In this connection, it is of particular interest, that this gravitational lensing effect may not only result in double or multiple images of the same object, but also that the intensities of these images increase significantly, just as it is the case with an ordinary optical lens. Distant galaxies, galaxy clusters, etc. may thereby act as natural telescopes which allow us to observe objects that would otherwise have been too faint to be detected with currently available astronomical telescopes. How to obtain ESO Press Information ESO Press Information is made available on the World-Wide Web (URL: http://www.eso.org../). ESO Press Photos may be reproduced, if credit is given to the European Southern Observatory.

  5. Mari Koger : "Arhitekte on palju. Tuleb leida õige" / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Mari Koger (sünd. 1973) kodu kujundamisest, planeerimisest, valgustusest, värvidest, suhtlemisest kliendiga. Mari Kogerist, loetletud tema tehtud ühiskondlike ruumide sisekujundused aastast 2002. M. Koger töötab Boom.ee OÜ-s. Ill.: M. Kogeri värv. portree

  6. Sanitation and recultivation of the Endlhausen landfill. Experience and hints

    Energy Technology Data Exchange (ETDEWEB)

    Hoerich, O; Rieger, W

    1986-02-01

    A landfill located in a former gravel pit was covered once 300,000 t of domestic refuse had been dumped. Drain pipes were laid for degassing the landfill. A clay layer was used to prevent surface water inroads. The article explains details and approaches. The cost are some DM 900,000 at an area of 3 ha. Grassing and planting will follow.

  7. Observational hints of radial migration in disc galaxies from CALIFA

    Science.gov (United States)

    Ruiz-Lara, T.; Pérez, I.; Florido, E.; Sánchez-Blázquez, P.; Méndez-Abreu, J.; Sánchez-Menguiano, L.; Sánchez, S. F.; Lyubenova, M.; Falcón-Barroso, J.; van de Ven, G.; Marino, R. A.; de Lorenzo-Cáceres, A.; Catalán-Torrecilla, C.; Costantin, L.; Bland-Hawthorn, J.; Galbany, L.; García-Benito, R.; Husemann, B.; Kehrig, C.; Márquez, I.; Mast, D.; Walcher, C. J.; Zibetti, S.; Ziegler, B.; Califa Team

    2017-07-01

    Context. According to numerical simulations, stars are not always kept at their birth galactocentric distances but they have a tendency to migrate. The importance of this radial migration in shaping galactic light distributions is still unclear. However, if radial migration is indeed important, galaxies with different surface brightness (SB) profiles must display differences in their stellar population properties. Aims: We investigate the role of radial migration in the light distribution and radial stellar content by comparing the inner colour, age, and metallicity gradients for galaxies with different SB profiles. We define these inner parts, avoiding the bulge and bar regions and up to around three disc scale lengths (type I, pure exponential) or the break radius (type II, downbending; type III, upbending). Methods: We analysed 214 spiral galaxies from the CALIFA survey covering different SB profiles. We made use of GASP2D and SDSS data to characterise the light distribution and obtain colour profiles of these spiral galaxies. The stellar age and metallicity profiles were computed using a methodology based on full-spectrum fitting techniques (pPXF, GANDALF, and STECKMAP) to the Integral Field Spectroscopic CALIFA data. Results: The distributions of the colour, stellar age, and stellar metallicity gradients in the inner parts for galaxies displaying different SB profiles are unalike as suggested by Kolmogorov-Smirnov and Anderson-Darling tests. We find a trend in which type II galaxies show the steepest profiles of all, type III show the shallowest, and type I display an intermediate behaviour. Conclusions: These results are consistent with a scenario in which radial migration is more efficient for type III galaxies than for type I systems, where type II galaxies present the lowest radial migration efficiency. In such a scenario, radial migration mixes the stellar content, thereby flattening the radial stellar properties and shaping different SB profiles. However, in light of these results we cannot further quantify the importance of radial migration in shaping spiral galaxies, and other processes, such as recent star formation or satellite accretion, might play a role. Based on observations collected at the Centro Astronómico Hispano Alemán (CAHA) at Calar Alto, operated jointly by the Max-Planck Institut für Astronomie and the Instituto de Astrofísica de Andalucía (CSIC).Table 1 is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/604/A4

  8. Observational hints of radial migration in disc galaxies from CALIFA

    NARCIS (Netherlands)

    Ruiz-Lara, T.; Pérez, I.; Florido, E.; Sánchez-Blázquez, P.; Méndez-Abreu, J.; Sánchez-Menguiano, L.; Sánchez, S. F.; Lyubenova, M.; Falcón-Barroso, J.; van de Ven, G.; Marino, R. A.; de Lorenzo-Cáceres, A.; Catalán-Torrecilla, C.; Costantin, L.; Bland-Hawthorn, J.; Galbany, L.; García-Benito, R.; Husemann, B.; Kehrig, C.; Márquez, I.; Mast, D.; Walcher, C. J.; Zibetti, S.; Ziegler, B.

    2017-01-01

    Context. According to numerical simulations, stars are not always kept at their birth galactocentric distances but they have a tendency to migrate. The importance of this radial migration in shaping galactic light distributions is still unclear. However, if radial migration is indeed important,

  9. 3rd Circuit hints it may reconsider McNemar reasoning.

    Science.gov (United States)

    1997-10-17

    The [name removed] v. The Disney Store ruling is under criticism and the 3rd U.S. Circuit Court of Appeals may reconsider its 1996 decision to not allow employees who receive disability benefits to sue under the Americans with Disabilities Act (ADA). A panel of 3rd Circuit judges, working on [name removed] v. American Sterilizer Co., asserts that the [name removed] decision should not be used to assume that an individual's ADA claims are barred because of prior representations of disability. [Name removed] is suing American Sterilizer under the retaliation provisions of the ADA. Other courts are criticizing the [name removed] decision, including the District of Columbia Court in [name removed] v. Washington Metropolitan Area Transit Authority. The [name removed] court assets that a statement made in the context of a disability application does not preclude an ADA claim brought by a worker for illegal discrimination because the ADA and the Social Security Act differ in their statutory intent. AIDS advocates state that the [name removed] decision places a plaintiff in the position of having to choose between asserting a legal right or maintaining an income. Alan Epstein, who represented [name removed], is pleased by the criticism but explains that [name removed], who died this summer, will not be vindicated.

  10. Andro Kööp : villa, mis sai ajaloo / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Saaremaal asuva arhitekt Ike Volkovi projekti järgi ehitatud villa sisekujundus. Sisearhitekt Andro Kööp, tema kommentaarid. A. Kööp on kavandanud ka vaibad. Suures osas on villa sisekujunduses kasutatud kataloogimööblit. Ill.: I ja II korruse plaan, 17 värv. vaadet

  11. Bs Physics at LEP, SLD, and CDF Delta m_s and Delta Gamma_s

    CERN Document Server

    Boix, G

    2001-01-01

    The current status of the experimental knowledge of $\\Bs$ meson physics is reviewed. Results from LEP and CDF on the width difference $\\dgs$ are presented, the corresponding average is found to be in good agreement with the present theoretical estimation. The $\\Bs$ oscillations have not yet been resolved, despite the progress recently achieved by SLD and ALEPH. The world combination, including results from the LEP experiments, SLD and CDF, is presented, together with the expected and observed lower limit on the $\\Bs$ oscillation frequency. A tantalizing hint of an oscillation is observed around $\\dms\\sim17 \\psin$, near future results could increase the significance of this hint.

  12. Estimativa de Parâmetros Biofísicos de Povoamentos de Eucalyptus Através de Dados SAR / Estimation of Biophysical Parameters in the Eucalyptus Stands by SAR Data

    Directory of Open Access Journals (Sweden)

    Fábio Furlan Gama

    2006-10-01

    Full Text Available O objetivo deste trabalho foi estabelecer as relações entre os parâmetros dendométricos de florestas e a resposta da radiometria e da interferometria obtidas por sensores SAR (Synthetic Aperture Radar, utilizando técnicas de regressão multivariada. Uma área de povoamento de Eucalyptus grandis, com 6,1 anos de plantio, foi selecionada para estudo. Os resultados indicaram que o volume das parcelas foi altamente correlacionado com o logaritmo da altura interferométrica (LogHint obtida pela diferença entre os modelos interferométricos nas bandas X e P, enquanto que o DAP (Diâmetro à Altura do Peito apresentou melhor relação com a combinação da coerência interferométrica na banda PVV (CohPVV e o LogHint. A altura comercial da vegetação, similarmente ao DAP, foi melhor explicada com a combinação da CohPvv e o LogHint. Os resultados obtidos demonstraram que, devido ao povoamento ser constituído de indivíduos cuja estrutura era predominantemente cilíndrica de orientação vertical, houve uma maior interação com a polarização VV. Os resultados indicaram também que a resposta radiométrica na banda P, de maior comprimento de onda, não foi tão eficaz quanto a interferometria (CohPvv e o LogHint para estimativa dos parâmetros dendométricos estudados, obtendo índices de determinação de 84 a 88% em relação ao inventário florestal das áreas.

  13. Validating an electronic health literacy scale in an older hispanic population.

    Science.gov (United States)

    Aponte, Judith; Nokes, Kathleen M

    2017-09-01

    To examine the validity of the Spanish version of an instrument used to measure electronic health literacy (eHEALS) with an older Hispanic population from a number of Spanish-language countries living in New York City in the United States (US). Although the Internet is available globally, complex skills are needed to use this source of valuable health-related information effectively. Electronic health literacy is a multifactorial concept that includes health literacy but also requires technology skills. Cross-sectional. Recruitment occurred at a Senior Organization located in a largely Hispanic neighbourhood in New York City (N = 100). Participants completed eHEALS and selected items from the Health Information National Trends Survey (HINTS) which assesses how adults use different communication channels, including the Internet, to obtain vital health information. Data from the US HINTS sample (N = 162) were matched to the Senior Organization sample on age range and Hispanic ethnicity. The average Senior Organization participant was 68 years old, female, born in one of six different Spanish-language countries, and completed high school while the average HINTS participant was 67 years old, female and had high school or less education. Although there was no relationship with the two HINTS subscales and electronic health literacy, there were significant relationships between electronic health literacy and health status and confidence in self-care. Inadequate electronic health literacy is a barrier to positive health outcomes. The Spanish version of eHEALS could be used as a screening instrument to identify gaps and tailored interventions could be developed to increase consumer confidence in using the Internet for reliable health-related information. Knowledge in self-management is related to positive health outcomes; all persons irrespective of their electronic health literacy should be able to use all sources of health information to enhance their self-care.

  14. Improvements in speech understanding with wireless binaural broadband digital hearing instruments in adults with sensorineural hearing loss.

    Science.gov (United States)

    Kreisman, Brian M; Mazevski, Annette G; Schum, Donald J; Sockalingam, Ravichandran

    2010-03-01

    This investigation examined whether speech intelligibility in noise can be improved using a new, binaural broadband hearing instrument system. Participants were 36 adults with symmetrical, sensorineural hearing loss (18 experienced hearing instrument users and 18 without prior experience). Participants were fit binaurally in a planned comparison, randomized crossover design study with binaural broadband hearing instruments and advanced digital hearing instruments. Following an adjustment period with each device, participants underwent two speech-in-noise tests: the QuickSIN and the Hearing in Noise Test (HINT). Results suggested significantly better performance on the QuickSIN and the HINT measures with the binaural broadband hearing instruments, when compared with the advanced digital hearing instruments and unaided, across and within all noise conditions.

  15. Andes: An Intelligent Homework System for Introductory Physics

    Science.gov (United States)

    van de Sande, Brett; VanLehn, K.; Hausmann, R.; Treacy, D.; Shelby, R.

    2006-12-01

    We know that students benefit from solving homework problems under the guidance of an expert (human) tutor. The Andes system (http://www.andes.pitt.edu) is designed for students to solve homework problems under the guidance of an expert computer tutor. Andes encourages students to use sound problem solving techniques and provides immediate right/wrong feedback on each step of a solution. On request, Andes also provides hints based on previous student actions. I will discuss how Andes works, from a student's perspective, and summarize research that demonstrates its effectiveness as a pedagogical tool. I will also discuss how Andes can function as a tool for conducting educational research, presenting an investigation of students' hint usage as an example.

  16. Forschungszentrum Juelich, Institut fuer Kernphysik/COSY. Annual report 2007

    Energy Technology Data Exchange (ETDEWEB)

    Buescher, M.; Hanhart, C.; Krewald, S.; Machner, H.; Maier, R.; Meissner, U.G.; Ritman, J.; Stockhorst, H.; Stroeher, H. (eds.)

    2008-03-15

    The following topics are dealt with, Physics at COSY, external experiments, theoretical investigations. COSY operation and developments, preparation for FAIR. See hints under the relevant topics. (HSI)

  17. Forschungszentrum Juelich, Institut fuer Kernphysik/COSY. Annual report 2007

    International Nuclear Information System (INIS)

    Buescher, M.; Hanhart, C.; Krewald, S.; Machner, H.; Maier, R.; Meissner, U.G.; Ritman, J.; Stockhorst, H.; Stroeher, H.

    2008-03-01

    The following topics are dealt with, Physics at COSY, external experiments, theoretical investigations. COSY operation and developments, preparation for FAIR. See hints under the relevant topics. (HSI)

  18. Electronic Journals: Publishing via Internet's World Wide Web.

    Science.gov (United States)

    van Brakel, Pieter A.

    1995-01-01

    Provides hints for setting up and maintaining a multimedia scholarly journal. Details include limitations of paper and electronic journals, and requirements for publishing successful electronic journals. (JKP)

  19. Teaduste akadeemias austati Ahrensit / Allar Viivik

    Index Scriptorium Estoniae

    Viivik, Allar

    2015-01-01

    Eesti Teaduste Akadeemia saalis toimus konverents "Kummardus Ahrensile", sõnavõttude ja ettekannetega anti ülevaade Kuusalu pastori Eduard Ahrensi keelemehetööst. Ettekandega esines ka keelemees Mati Hint

  20. Kuidas Alfred Adler läks tülli Sigmund Freudiga / Aivar Kull

    Index Scriptorium Estoniae

    Kull, Aivar, 1955-

    1996-01-01

    Arvustus: Adler, Alfred. Inimesetundmine : Inimeste iseloomude peategurid ja nende areng / Tlk. Debora Hint. 2.tr. Tln. : Kupar, 1995. Vaata ka: Kull, Aivar. Kulli pilk. - Tartu : Ilmamaa, 2005, lk. 97-100

  1. Digital astrophotography the state of the art

    CERN Document Server

    Ratledge, David

    2005-01-01

    The CCD (Charge-Coupled Device) has revolutionised optical astronomy during the past 20 years, and specialised astronomical CCD cameras are now even more affordable, colour is standard, and they provide spectacular results. "Digital Astrophotography: The State of the Art", provides some examples of the best images, and gives readers hints and tips about how to get the best out of this extraordinary technology. Experts in CCD astronomy from North America and Europe have contributed to this book, illustrating their help and advice with many beautiful colour images - the book is in full colour throughout. Techniques range from using simple webcams to highly technical aspects such as supernovae patrolling. Computer processing, stacking and image-enhancement are detailed, along with many hints and tips from the experts.

  2. Non-Standard Hierarchies of the Runnings of the Spectral Index in Inflation

    Directory of Open Access Journals (Sweden)

    Chris Longden

    2017-03-01

    Full Text Available Recent analyses of cosmic microwave background surveys have revealed hints that there may be a non-trivial running of the running of the spectral index. If future experiments were to confirm these hints, it would prove a powerful discriminator of inflationary models, ruling out simple single field models. We discuss how isocurvature perturbations in multi-field models can be invoked to generate large runnings in a non-standard hierarchy, and find that a minimal model capable of practically realising this would be a two-field model with a non-canonical kinetic structure. We also consider alternative scenarios such as variable speed-of-light models and canonical quantum gravity effects and their implications for runnings of the spectral index.

  3. Heterogeneous rates for birth defects in Latin America: hints on causality.

    Science.gov (United States)

    Lopez-Camelo, J S; Orioli, I M

    1996-01-01

    The aim of this work was to disclose risk factors associated with birth defects which were heterogeneously distributed in the different geographic regions sampled by the Latin American Collaborative Study of Congenital Malformations (ECLAMC). The material included 2,159,065 hospital births, delivered in the 1967-1989 period in 24 geographic regions of Latin America. Birth defect types with 50 case-control pairs or more were analyzed. A risk factor was defined as that available variable with differential geographic rates, correlated with those of a given birth defect type. Identified factors were tested by case-control multivariate logistic regression to confirm their role in the occurrence of the defect. Altitude and maternal acute illness during first trimester of pregnancy, named influenza, were risk factors for microtia. Prenatal drug exposure, mainly sex hormones, were connected with the occurrence of hypospadias in low frequency areas, while Native ancestry was a "protective" factor in the same regions. Acute (influenza), and chronic (epilepsy and syphilis) maternal illness during first trimester of pregnancy and gravidity higher than four were risk factors for cleft lip. The independence of these variables from maternal age suggested that low maternal socioeconomic level could explain the high birth defect order and, perhaps, syphilis in mothers. Postaxial polydactyly was associated with parental consanguinity, as well as Afro-American ancestry, suggesting genetic heterogeneity.

  4. Design of sweet protein based sweeteners: hints from structure-function relationships.

    Science.gov (United States)

    Rega, Michele Fortunato; Di Monaco, Rossella; Leone, Serena; Donnarumma, Federica; Spadaccini, Roberta; Cavella, Silvana; Picone, Delia

    2015-04-15

    Sweet proteins represent a class of natural molecules, which are extremely interesting regarding their potential use as safe low-calories sweeteners for individuals who need to control sugar intake, such as obese or diabetic subjects. Punctual mutations of amino acid residues of MNEI, a single chain derivative of the natural sweet protein monellin, allow the modulation of its taste. In this study we present a structural and functional comparison between MNEI and a sweeter mutant Y65R, containing an extra positive charge on the protein surface, in conditions mimicking those of typical beverages. Y65R exhibits superior sweetness in all the experimental conditions tested, has a better solubility at mild acidic pH and preserves a significant thermal stability in a wide range of pH conditions, although slightly lower than MNEI. Our findings confirm the advantages of structure-guided protein engineering to design improved low-calorie sweeteners and excipients for food and pharmaceutical preparations. Copyright © 2014 Elsevier Ltd. All rights reserved.

  5. Supportive hints in a digital learning environment : Effects on students' motivation

    NARCIS (Netherlands)

    ter Beek, Marlies; Brummer, Leonie; Donker-Bergstra, Anouk; Opdenakker, Marie-christine

    2017-01-01

    Reading skills are developed across the lifespan. However, little is known about the development of reading comprehension skills and materials in secondary education, where students do not learn to read, but read to learn. When students read informational textbooks, domain knowledge (e.g., about

  6. Search for Z′, vacuum (instability and hints of high-energy structures

    Directory of Open Access Journals (Sweden)

    Accomando Elena

    2016-01-01

    Full Text Available We study the high-energy behaviour of a class of anomaly-free abelian extensions of the Standard Model. We focus on the interplay among the phenomenological characterisation of the model and the use of precise renormalisation group methods. Using as boundary conditions regions of the parameter space at the verge of current LHC probe, interesting unification patterns emerge linked to thresholds belonging to a SO(10 grand unification theory (GUT. We stress how the evolution of the mixing between the two abelian factors may provide a valuable tool to address the candidate high-energy embedding. The emerging unification scenarios are then challenged to be perturbative and to allow for a stable vacuum.

  7. Breastfeeding: Hints to Help You Get Off to a Good Start

    Science.gov (United States)

    ... Kids and Teens Pregnancy and Childbirth Women Men Seniors Your Health Resources Healthcare Management End-of-Life Issues Insurance & Bills Self Care Working With Your Doctor Drugs, Procedures & Devices Over-the- ...

  8. Eesti identiteedi kasv ja kasvatus 2006. aastal - Kumust Brotzeni / Mati Hint

    Index Scriptorium Estoniae

    Hint, Mati, 1937-

    2006-01-01

    Tallinna Ülikooli emeriitprofessori loetletud tippsündmused Eesti kunsti ja ajaloo valdkonnas 2006. a. - Kumu Kunstimuuseumi avamine, Kristjan ja Paul Raua näitus Kumus ning Riias tegutsenud baltisaksa kultuuriloolase Johann Christoph Brotze joonistuste kogumiku "Johann Christoph Brotze. Estonica." Koostanud Ants Hein, Ivar Leimus, Raimo Pullat, Ants Viires. Estopol OÜ 2006, ilmumine Tallinnas, peatoimetaja Raimo Pullat. Pikemalt eesti nüüdisaegsest kunstist Kumus ja rahvuslikust identiteedist

  9. Õun. Minu kõige mõttetum ost : [jutt] / Anna Hints

    Index Scriptorium Estoniae

    Hints, Anna

    2006-01-01

    Sisu: Juuli 2004 ; August 2004 ; September 2004 ; September 2004, kuskil keskel ; September 2004, lõpus ; Oktoober 2004, 1. nädal ; Oktoober 2004, 2. nädal ; Oktoober 2004, 3. nädala alguses ; Oktoober 2004, 3. nädala lõpupoole ; Oktoober 2004, 4. nädal ; November 2004, 1. nädal ; November 2004, lõpp ; Jaanuar 2005, täna

  10. HEALTH INFO SANTE ANNUAL DEDUCTIBLE AND REIMBURSEMENT CLAIMS: HINTS FOR USE

    CERN Multimedia

    1999-01-01

    Information from the CHIS Board and the Personnel DivisionOne should bear in mind that the annual deductible is an amount (currently CHF 100) charged automatically by the Administrator of the scheme for every adult aged 18 and above. This is what happens: The amount is deducted annually for all medical services received over a calendar year.It is triggered by the date of the treatment and not by the date of the bill nor that of the reimbursement claim.In other words, if you receive medical treatment in December for the first time in a given year, the CHF 100 will be deducted from the claim for that treatment. So, except for urgent cases, it would be better to wait till the following month, thus avoiding one annual deductible.It is also worth remembering that the cost of processing our reimbursement claims - and there were 55, 000 in 1998 - is part of the cost of our insurance.Help keep administrative costs down : do not submit reimbursement claims for amounts less than the annual deductible unless your claims...

  11. Association of tinnitus and electromagnetic hypersensitivity: hints for a shared pathophysiology?

    Directory of Open Access Journals (Sweden)

    Michael Landgrebe

    Full Text Available BACKGROUND: Tinnitus is a frequent condition with high morbidity and impairment in quality of life. The pathophysiology is still incompletely understood. Electromagnetic fields are discussed to be involved in the multi-factorial pathogenesis of tinnitus, but data proofing this relationship are very limited. Potential health hazards of electromagnetic fields (EMF have been under discussion for long. Especially, individuals claiming themselves to be electromagnetic hypersensitive suffer from a variety of unspecific symptoms, which they attribute to EMF-exposure. The aim of the study was to elucidate the relationship between EMF-exposure, electromagnetic hypersensitivity and tinnitus using a case-control design. METHODOLOGY: Tinnitus occurrence and tinnitus severity were assessed by questionnaires in 89 electromagnetic hypersensitive patients and 107 controls matched for age-, gender, living surroundings and workplace. Using a logistic regression approach, potential risk factors for the development of tinnitus were evaluated. FINDINGS: Tinnitus was significantly more frequent in the electromagnetic hypersensitive group (50.72% vs. 17.5% whereas tinnitus duration and severity did not differ between groups. Electromagnetic hypersensitivity and tinnitus were independent risk factors for sleep disturbances. However, measures of individual EMF-exposure like e.g. cell phone use did not show any association with tinnitus. CONCLUSIONS: Our data indicate that tinnitus is associated with subjective electromagnetic hypersensitivity. An individual vulnerability probably due to an over activated cortical distress network seems to be responsible for, both, electromagnetic hypersensitivity and tinnitus. Hence, therapeutic efforts should focus on treatment strategies (e.g. cognitive behavioral therapy aiming at normalizing this dysfunctional distress network.

  12. Flexibility of approach in art practice as research: Hints in Omabe ...

    African Journals Online (AJOL)

    Recently, a number of art institutions (universities) in Europe, America, Asia, and Africa, introduced doctorate programme in studio areas, in which art practice is considered as research. As a new ... installation. The installations elicited public discourse on the tradition and a language of practice stood out from them.

  13. Mari Koger : avatud magamistoaga korter pööningukorrusel / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Korter Nõmmel renoveeritud puumajas (arhitekt Hannes Niineväli). Sisearhitekt Mari Koger, tema kommentaarid. Söögilaua alumiiniumist valatud jalgade autor on Taavi Aunre. Söögilauda valgustab Alberto Meda ja Paolo Rizzatto disainitud lamp Titania. Ill.: plaan, 8 värv. vaadet

  14. Estimating Dynamical Systems: Derivative Estimation Hints from Sir Ronald A. Fisher

    Science.gov (United States)

    Deboeck, Pascal R.

    2010-01-01

    The fitting of dynamical systems to psychological data offers the promise of addressing new and innovative questions about how people change over time. One method of fitting dynamical systems is to estimate the derivatives of a time series and then examine the relationships between derivatives using a differential equation model. One common…

  15. ECOOL 1984

    International Nuclear Information System (INIS)

    Poth, H.

    1984-07-01

    These proceedings contain the articles presented at the named workshop. They deal with electron cooling and its applications, especially in heavy ion storage rings. See hints under the relevant topics. (HSI)

  16. Scattering of highly excited atoms

    International Nuclear Information System (INIS)

    Raith, W.

    1980-01-01

    Experimental methods to excite atomic beams into Rydberg states and the first results of collision experiments with such beams are reported. For further information see hints under relevant topics. (orig.) [de

  17. An introduction to linear algebra and tensors

    CERN Document Server

    Akivis, M A; Silverman, Richard A

    1978-01-01

    Eminently readable, completely elementary treatment begins with linear spaces and ends with analytic geometry, covering multilinear forms, tensors, linear transformation, and more. 250 problems, most with hints and answers. 1972 edition.

  18. The International Criminal Court: Why We Need It, How We Got It, Our Concern About It

    National Research Council Canada - National Science Library

    MacCuish, Donald A; Hater, David A; Dubriske, Steven D; Ruby, Tomislav

    2005-01-01

    ... extreme. The problem with judicial proceedings is that they can have a hint of victor's justice, especially if the jurisdiction, legitimacy, and authority of the court are not established in advance...

  19. Are demand forecasting techniques applicable to libraries?

    OpenAIRE

    Sridhar, M. S.

    1984-01-01

    Examines the nature and limitations of demand forecasting, discuses plausible methods of forecasting demand for information, suggests some useful hints for demand forecasting and concludes by emphasizing unified approach to demand forecasting.

  20. 80th Annual Meeting | Annual Meetings | Events | Indian Academy of ...

    Indian Academy of Sciences (India)

    Current status and future prospects of neutrino mass measurement. View presentation ... Business Meeting of Fellows. 17.00. High Tea ... Hints of 'Beyond Standard Model' cosmology in the cosmic microwave background. View presentation.

  1. Can Biochemistry Usefully Guide the Search for Better Polymer Electrolytes?

    Directory of Open Access Journals (Sweden)

    J. Woods Halley

    2013-09-01

    Full Text Available I review some considerations that suggest that the biochemical products of evolution may provide hints concerning the way forward for the development of better electrolytes for lithium polymer batteries.

  2. Association between intimate partner violence & HIV/AIDS: Exploring the pathways in Indian context

    Directory of Open Access Journals (Sweden)

    Seema Patrikar

    2017-01-01

    Interpretation & conclusions: Significantly higher reporting of HIV/STIs by women experiencing IPV hints at new pathways that link violence and HIV. Further, our analysis showed a high prevalence of IPV in India.

  3. Different Facets of Body Image Disturbance in Binge Eating Disorder: A Review

    Science.gov (United States)

    Lewer, Merle; Bauer, Anika

    2017-01-01

    The goal of the present review is to give an overview of the current findings on various facets of body image disturbance in Binge Eating Disorder such as body dissatisfaction, overconcern with weight and shape, body-related checking and avoidance behavior, misperception of body size, and body-related cognitive bias. In addition, treatments for a disturbed body image in BED and evidence of body image disturbance in youth with binge eating are reviewed. The results show that a disturbed body image in BED is present in the form of overconcern with weight and shape. Furthermore, there are hints that body dissatisfaction, as well as body-related checking and avoidance behavior, are also impaired. Research concerning misperception of body size in BED has been neglected so far, but first findings show that individuals with BED rate their own body shape rather accurately. Furthermore, there are first hints that body-related cognitive biases are present in individuals with BED. Moreover, in children and adolescents, there are first hints that body dissatisfaction, as well as shape and weight concerns, seem to be associated with loss of control and binge eating. Treatments aimed directly at the convertibility of a disturbed body image in BED have revealed encouraging outcomes. In conclusion, body image disturbance seems to occur in BED, and first studies show that it can be treated effectively. PMID:29182531

  4. Different Facets of Body Image Disturbance in Binge Eating Disorder: A Review

    Directory of Open Access Journals (Sweden)

    Merle Lewer

    2017-11-01

    Full Text Available The goal of the present review is to give an overview of the current findings on various facets of body image disturbance in Binge Eating Disorder such as body dissatisfaction, overconcern with weight and shape, body-related checking and avoidance behavior, misperception of body size, and body-related cognitive bias. In addition, treatments for a disturbed body image in BED and evidence of body image disturbance in youth with binge eating are reviewed. The results show that a disturbed body image in BED is present in the form of overconcern with weight and shape. Furthermore, there are hints that body dissatisfaction, as well as body-related checking and avoidance behavior, are also impaired. Research concerning misperception of body size in BED has been neglected so far, but first findings show that individuals with BED rate their own body shape rather accurately. Furthermore, there are first hints that body-related cognitive biases are present in individuals with BED. Moreover, in children and adolescents, there are first hints that body dissatisfaction, as well as shape and weight concerns, seem to be associated with loss of control and binge eating. Treatments aimed directly at the convertibility of a disturbed body image in BED have revealed encouraging outcomes. In conclusion, body image disturbance seems to occur in BED, and first studies show that it can be treated effectively.

  5. Data processing framework for decision making

    DEFF Research Database (Denmark)

    Larsen, Jan

    The aim of the talk is * to provide insight into some of the issues in data processing and detection systems * to hint at possible solutions using statistical signal processing and machine learning methodologies...

  6. Crystal Ball contributions to the 9th international workshop on photon-photon collisions, La Jolla, 23-26 March 1992

    International Nuclear Information System (INIS)

    Bienlein, J.K.

    1992-06-01

    This report contains two articles concerning new Crystal Ball data on resonance formation by γγ collisions and the representation of such results by helicity amplitudes. See hints under the relevant topics. (HSI)

  7. Email: pattuquayefio@ug.edu.gh

    African Journals Online (AJOL)

    Apusigah

    making. ... study, the article hints at possible implications of the co-optation of human ... shortage, health challenges such as the Human Immunodeficiency Virus (HIV), and the causes ... appropriate framework for considering such challenges.

  8. Spectroscopy and Photometry of CAI-rich asteroids

    Science.gov (United States)

    Tanga, P.; Devogele, M.; Bendjoya, Ph.; Cellino, A.; Surdej, J.

    2017-09-01

    Asteroids with an anomalous amount of primitive elements, formed in ancient times in the solar nebula, exist. Our study confirms their nature and provides hints to the interpretation of the ancient evolution of asteroids.

  9. No Appetite? How to Get Nutrition during Cancer Treatment

    Science.gov (United States)

    ... than to eat something. During illness, treatment or recovery, your need for calories and protein may be ... patient-education/eating-hints. Accessed Jan. 5, 2015. Nutrition in cancer care (PDQ). National Cancer Institute. http:// ...

  10. Keeletammik sai järjekordse nimipuu / Kristi Ehrlich

    Index Scriptorium Estoniae

    Ehrlich, Kristi, 1979-

    2009-01-01

    Väike-Maarjas peetud Wiedemanni keelepäevast, kus pidas ettekande ka tänavune keeleauhinna laureaat, Ohio ülikooli professor Ilse Lehiste. Keelekonverentsist võttis osa ka keeleteadlane ja TLÜ emeriitprofessor Mati Hint

  11. F. J. Wiedemanni keeleauhind on lakanud. Elagu F. J. Wiedemanni keeleauhind! / Eevi Ross

    Index Scriptorium Estoniae

    Ross, Eevi

    2003-01-01

    15-ndad ja viimased F. J. Wiedemanni Keeleauhinna Sihtasutuse laureaadid on Mati Hint ja Helju Vals, järgmisel aastal antakse välja esimene riiklik F. J. Wiedemanni keeleauhind Eesti Vabariigi peaministri poolt

  12. Binaural Interference and the Effects of Age and Hearing Loss.

    Science.gov (United States)

    Mussoi, Bruna S S; Bentler, Ruth A

    2017-01-01

    The existence of binaural interference, defined here as poorer speech recognition with both ears than with the better ear alone, is well documented. Studies have suggested that its prevalence may be higher in the elderly population. However, no study to date has explored binaural interference in groups of younger and older adults in conditions that favor binaural processing (i.e., in spatially separated noise). Also, the effects of hearing loss have not been studied. To examine binaural interference through speech perception tests, in groups of younger adults with normal hearing, older adults with normal hearing for their age, and older adults with hearing loss. A cross-sectional study. Thirty-three participants with symmetric thresholds were recruited from the University of Iowa community. Participants were grouped as follows: younger with normal hearing (18-28 yr, n = 12), older with normal hearing for their age (73-87 yr, n = 9), and older with hearing loss (78-94 yr, n = 12). Prior noise exposure was ruled out. The Connected Speech Test (CST) and Hearing in Noise Test (HINT) were administered to all participants bilaterally, and to each ear separately. Test materials were presented in the sound field with speech at 0° azimuth and the noise at 180°. The Dichotic Digits Test (DDT) was administered to all participants through earphones. Hearing aids were not used during testing. Group results were compared with repeated measures and one-way analysis of variances, as appropriate. Within-subject analyses using pre-established critical differences for each test were also performed. The HINT revealed no effect of condition (individual ear versus bilateral presentation) using group analysis, although within-subject analysis showed that 27% of the participants had binaural interference (18% had binaural advantage). On the CST, there was significant binaural advantage across all groups with group data analysis, as well as for 12% of the participants at each of the two

  13. Res Publica hakkab kaaluma Kohtla-Järve võimuliidust lahkumist / Erik Gamzejev

    Index Scriptorium Estoniae

    Gamzejev, Erik, 1967-

    2002-01-01

    Ilmunud ka: Severnoje Poberezhje 19. nov. lk. 1. Res Publica eestseisuse ettepanek Kohtla-Järve osakonnale lahkuda koalitsioonist. Osakonna juhatuse otsus esitada Hants Hint volikogu esimehe kandidaadiks. Res Publica liikmete käitumise arutelu aukohtus

  14. An introduction to the theory of linear spaces

    CERN Document Server

    Shilov, Georgi E

    1975-01-01

    Introductory treatment offers a clear exposition of algebra, geometry, and analysis as parts of an integrated whole rather than separate subjects. Numerous examples illustrate many different fields, and problems include hints or answers. 1961 edition.

  15. Calculus of variations mechanics, control and other applications

    CERN Document Server

    MacCluer, Charles R

    2012-01-01

    First truly up-to-date treatment offers a simple introduction to optimal control, linear-quadratic control design, and more. Broad perspective features numerous exercises, hints, outlines, and appendixes, including a practical discussion of MATLAB. 2005 edition.

  16. evaluation of total annual costs of heat exchanger networks using

    African Journals Online (AJOL)

    user

    after solving the first problem using RPA based heat integration gave a minimum total annual cost (TAC) of $237, ... mathematical programming and non-RPA based Hint software. ... The concept of pinch analysis evolved over the years.

  17. Maximizing your teaching moment

    Science.gov (United States)

    ... may help to give your patient written or audiovisual resources before your meeting. This may help reduce ... As you are teaching, provide reinforcement for learning. Reinforce your ... Offer hints, tips, and strategies that you have gathered ...

  18. The amateur astronomer

    CERN Document Server

    Moore, Patrick

    2006-01-01

    Introduces astronomy and amateur observing together. This edition includes photographs and illustrations. The comprehensive appendices provide hints and tips, as well as data for every aspect of amateur astronomy. This work is useful for amateur astronomers

  19. Kleit Evelinile / Britt Rosen

    Index Scriptorium Estoniae

    Rosen, Britt, 1968-

    2009-01-01

    Moekunstnikud Aldo Järvsoo, Kirill Safonov, Anu Samarüütel-Long, Anu Hint, Reet Aus, Anne Metsis, Xenia Jedomskihh, Kätlin Kaljuvee ja Mari Aakre joonistasid proua Evelin Ilvesele vabariigi aastapäeva vastuvõtuks õhtukleidi

  20. Tracking Code for Microwave Instability

    International Nuclear Information System (INIS)

    Heifets, S.; SLAC

    2006-01-01

    To study microwave instability the tracking code is developed. For bench marking, results are compared with Oide-Yokoya results [1] for broad-band Q = 1 impedance. Results hint to two possible mechanisms determining the threshold of instability

  1. Johannes Hindi tütar Pille Pae : inimlik headus ei sõltu režiimist / Pille Pae ; interv. Anneli Ammas

    Index Scriptorium Estoniae

    Pae, Pille

    2006-01-01

    Desintegraatori juhi Johannes Hindi tütar Pille Pae vastab küsimustele, mis puudutavad tema isa armuandmispalve esitamist, isale toetusallkirjade kogumist, Arnold Rüütli suhteid Johannes Hindiga. Lisa: Kes oli Johannes Hint ja mis Desintegraator?

  2. 17 Human Resource Development and the Productivity of the Civil ...

    African Journals Online (AJOL)

    FIRST LADY

    2011-01-18

    Jan 18, 2011 ... Civil Service of Cross River State, Nigeria (Pp. 17-24). Egbe ... knowledge content an employee possesses is the quality of training and retraining the ... offered useful hints that ensured standards that eventually aided the final.

  3. Gross properties of nuclei and nuclear excitations XXI

    International Nuclear Information System (INIS)

    Feldmeier, H.

    1993-01-01

    These proceedings contain the articles and contributed papers presented at the named workshop. They are concerned with highly excited nuclear matter and relativistic heavy ion reactions together with some related topics. See hints under the relevant topics. (HSI)

  4. Experiments at CERN in 1981

    International Nuclear Information System (INIS)

    1981-08-01

    This report contains the preliminary abstracts of the current experiments at the CERN SPS synchrotron, the anti p colliding beams, the CERN ISR, the CERN PS synchrotron, and the CERN synchrocyclotron. See hints under the relevant topics. (HSI)

  5. Fulltext PDF

    Indian Academy of Sciences (India)

    Madhu

    humans and animals against excessive pulmonary pressures and prevent the occurrence of .... Natural stimulation of J receptors produces dry cough in addition to .... committees and meetings his eyes would blaze with anger at the first hint of ...

  6. Report on the meeting of the working groups on neutron scattering applied to studying condensed matter, and neutron scattering and complementary methods applied in chemistry and biology

    International Nuclear Information System (INIS)

    1985-06-01

    The present volume consists of 55 lectures. The subjects are: 1) Elastic neutron diffraction, 2) Lattice dynamics, 3) Diffusion, 4) Polymers, 5) Biology, 6) Methods and tools, 7) Magnetism. For distinct papers see hints under relevant topics. (BHO)

  7. Impact of hydrogen onboard storage technologies on the performance of hydrogen fuelled vehicles: A techno-economic well-to-wheel assessment

    NARCIS (Netherlands)

    de Wit, M.P.; Faaij, A.P.C.

    2007-01-01

    Hydrogen onboard storage technologies form an important factor in the overall performance of hydrogen fuelled transportation, both energetically and economically. Particularly, advanced storage options such as metal hydrides and carbon nanotubes are often hinted favourable to conventional, liquid

  8. Trichoepithelioma And Multiple Basal Cell Epithelioma

    Directory of Open Access Journals (Sweden)

    Dey S.K

    1996-01-01

    Full Text Available A combination of multiple trichoepithelioma and basal cell epithelioma is reported. Although malignant degeneration of trichoepithelioma is debated, clinical and histopathological studies, in our case, hint at that. The case is reported for its rarity.

  9. Users guide for the ANL IBM SPx

    Energy Technology Data Exchange (ETDEWEB)

    Gropp, W.; Lusk, E.

    1994-12-01

    This guide presents the features of the IBM SPx installed in the Mathematics and Computer Science Division at Argonne National Laboratory. The guide describes the available hardware and software, access policies, and hints for using the system productively.

  10. Johannes Hindi tütar Pille Pae : inimlik headus ei sõltu rezhiimist / Pille Pae ; interv. Anneli Ammas

    Index Scriptorium Estoniae

    Pae, Pille

    2006-01-01

    Desintegraatori juhi Johannes Hindi tütar Pille Pae vastab küsimustele, mis puudutavad tema isa armuandmispalve esitamist, isale toetusallkirjade kogumist ning Arnold Rüütli suhteid Johannes Hindiga. Lisa: Kes oli Johannes Hint ja mis Desintegraator?

  11. Toward a more comprehensive understanding of the impact of masker type and signal-to-noise ratio on the pupillary response while performing a speech-in-noise test

    DEFF Research Database (Denmark)

    Wendt, Dorothea; Koelewijn, Thomas; Książek, Patrycja

    2018-01-01

    intelligibility. In a second experiment, effects of SNR on listening effort were examined while presenting the HINT sentences across a broad range of fixed SNRs corresponding to intelligibility scores ranging from 100 % to 0 % correct performance. A peak pupil dilation (PPD) was calculated and a Growth Curve...... Analysis (GCA) was performed to examine listening effort involved in speech recognition as a function of SNR. The results of two experiments showed that the pupil dilation response is highly affected by both masker type and SNR when performing the HINT. The PPD was highest, suggesting the highest level...... strongly varied as a function of SNRs. Listening effort was highest for intermediate SNRs with performance accuracies ranging between 30 % -70 % correct. GCA revealed time-dependent effects of the SNR on the pupillary response that were not reflected in the PPD....

  12. The chemistry of Li/SOCl2 cells - An ESR study of carbon electrodes

    Science.gov (United States)

    Kim, S. S.; Carter, B. J.; Tsay, F. D.

    1985-01-01

    Carbon electrodes from Li/SOCl2 cells were studied by electron spin resonance after various stages of discharge. Different behavior was observed in the temperature-dependent part of the ESR linewidth, defined as 'intrinsic linewidth', Delta H(int), when two different electrolytes were used. With one electrolyte, 1.5M LiAlCl4/SoCl2, the Delta H(int) value stayed constant or slightly decreased whereas with another electrolyte, 1.0M LiAlCl4/14 percent BrClin SOCl2, the value increased as discharge progressed. The carbon electrodes are modified differently during discharge with these two electrolytes, and it is speculated that this may be due to changes in the carbon matrix functional groups. This difference in the carbon electrodes may explain the claimed differences in safety performance of the cells.

  13. Search for new physics with $b \\to s \\ell^+ \\ell^-$ decays at LHCb

    CERN Multimedia

    CERN. Geneva

    2017-01-01

    The family of decays mediated by $b \\to s \\ell^+ \\ell^-$ transitions provides a rich laboratory to search for effects of physics beyond the Standard Model. In recent years LHCb has found hints of deviations from theoretical predictions both in the rates and angular distributions of such processes. In addition, hints of lepton flavour non-universality have been seen when comparing $B^+ \\to K^+\\mu^+\\mu^-$ and $B^+ \\to K^+e^+e^-$ decay rates, with the so-called $R_K$ ratio. Similar observables in different decays, such as $R_{K^\\ast} = \\mathrm{BR}(B^0 \\to K^{\\ast 0}\\mu^+\\mu^-) / \\mathrm{BR}(B^0 \\to K^{\\ast 0}e^+e^-)$ and others, can also be measured by LHCb, thus providing further avenues to test the effectiveness of lepton flavour universality. The latest results from LHCb in this sector will be presented.

  14. Filmil on Sõpruse kinos kohtumine - ta kohtub fotoga

    Index Scriptorium Estoniae

    2011-01-01

    Eesti esimesest fotofilmide festivalist 14. okt.-l Tallinnas kinos Sõprus, tutvustavad kuraatorid Anna Hints ja Alis Mäesalu. Lühidalt eesti fotofilmi ajaloost, rahvusvahelisest fotofimide konkursist "Ajatu lugu". Seminaril ettekanded Liina Siibilt ja Gusztáv Hámosilt (Saksamaa)

  15. Towards rare-earth-ion-doped Al2O3 active integrated optical devices

    OpenAIRE

    Ay, F.; Bradley, J.; Worhoff, Kerstin; Pollnau, Markus

    2007-01-01

    Aluminum oxide planar waveguides with low loss (0.11 dB/cm at 1523 nm) are fabricated. Channel waveguides are obtained by reactive ion etching. Erbium-doped layers show no upconversion luminescence, a hint that ion clustering is small.

  16. Theory of elementary particles. Proceedings

    International Nuclear Information System (INIS)

    Luest, D.; Weigt, G.

    1994-03-01

    These proceedings contain most of the invited talks ans short communications presented at the named symposium. These concern developments in field theory in connection with string models, grand unification, and quantum gravity. See hints under the relevant topics. (HSI)

  17. Hints for Small Disks around Very Low Mass Stars and Brown Dwarfs

    Energy Technology Data Exchange (ETDEWEB)

    Hendler, Nathanial P.; Mulders, Gijs D.; Pascucci, Ilaria [Lunar and Planetary Laboratory, The University of Arizona, Tucson, AZ 85721 (United States); Greenwood, Aaron; Kamp, Inga [Kapteyn Astronomical Institute, University of Groningen, Postbus 800, 9700 AV Groningen (Netherlands); Henning, Thomas [Max Planck Institute for Astronomy, Konigstuhl 17, D-69117 Heidelberg (Germany); Ménard, François [Univ. Grenoble Alpes, CNRS, IPAG, F-38000 Grenoble (France); Dent, William R. F. [Department of Engineering, Atacama Large Millimeter/submillimeter Array (ALMA) Santiago Central Offices, Alonso de Córdova 3107, Vitacura, Casilla 763 0355, Santiago (Chile); II, Neal J. Evans, E-mail: equant@lpl.arizona.edu [Department of Astronomy, The University of Texas at Austin, Austin, TX 78712 (United States)

    2017-06-01

    The properties of disks around brown dwarfs and very low mass stars (hereafter VLMOs) provide important boundary conditions on the process of planet formation and inform us about the numbers and masses of planets than can form in this regime. We use the Herschel Space Observatory PACS spectrometer to measure the continuum and [O i] 63 μ m line emission toward 11 VLMOs with known disks in the Taurus and Chamaeleon I star-forming regions. We fit radiative transfer models to the spectral energy distributions of these sources. Additionally, we carry out a grid of radiative transfer models run in a regime that connects the luminosity of our sources with brighter T Tauri stars. We find that VLMO disks with sizes 1.3–78 au, smaller than typical T Tauri disks, fit well the spectral energy distributions assuming that disk geometry and dust properties are stellar mass independent. Reducing the disk size increases the disk temperature, and we show that VLMOs do not follow previously derived disk temperature–stellar luminosity relationships if the disk outer radius scales with stellar mass. Only 2 out of 11 sources are detected in [O i] despite a better sensitivity than was achieved for T Tauri stars, suggesting that VLMO disks are underluminous. Using thermochemical models, we show that smaller disks can lead to the unexpected [O i] 63 μ m nondetections in our sample. The disk outer radius is an important factor in determining the gas and dust observables. Hence, spatially resolved observations with ALMA—to establish if and how disk radii scale with stellar mass—should be pursued further.

  18. Hints of hybridizing Majorana fermions in a nanowire coupled to superconducting leads

    Science.gov (United States)

    Finck, A. D. K.; van Harlingen, D. J.; Mohseni, P. K.; Jung, K.; Li, X.

    2013-03-01

    It has been proposed that a nanowire with strong spin-orbit coupling that is contacted with a conventional superconductor and subjected to a large magnetic field can be driven through a topological phase transition. In this regime, the two ends of the nanowire together host a pair of quasi-particles known as Majorana fermions (MFs). A key feature of MFs is that they are pinned to zero energy when the topological nanowire is long enough such that the wave functions of the two MFs do not overlap significantly, resulting in a zero bias anomaly (ZBA). It has been recently predicted that changes in external parameters can vary the wave function overlap and cause the MFs to hybridize in an oscillatory fashion. This would lead to a non-monotonic splitting or broadening of the ZBA and help distinguish MF transport signatures from a Kondo effect. Here, we present transport studies of an InAs nanowire contacted with niobium nitride leads in high magnetic fields. We observe a number of robust ZBAs that can persist for a wide range of back gate bias and magnetic field strength. Under certain conditions, we find that the height and width of the ZBA can oscillate with back gate bias or magnetic field. This work was supported by Microsoft Project Q.

  19. Cutaneous melanoma: hints from occupational risks by anatomic site in Swedish men

    Science.gov (United States)

    Perez-Gomez, B; Pollan, M; Gustavsson, P; Plato, N; Aragones, N; Lopez-Abente, G

    2004-01-01

    Aims: To improve knowledge of the epidemiology of melanoma by comparing occupational risks of cutaneous melanoma (CM) by anatomic site in Swedish workers. Methods: Male workers employed in 1970 and living in the country in 1960 were followed up from 1971 to 1989 using the Swedish Registers of Death and Cancer. A more specifically exposed subcohort included men reporting the same occupation in 1960 and 1970. For each location, occupational risk ratios (RRs) were extracted from Poisson regression models adjusted by age, period, town size, and geographical area. To diminish the influence of socioeconomic factors, intrasector analyses, comparing only jobs belonging to the same occupational sector, were performed. Risk patterns for different locations were compared. Results: High RRs for different sites were found among workers exposed to UV sources (dentists, physiotherapists, and lithographers), and sun exposed workers (harbour masters, and lighthouse/related work). Risk excesses were seen in fur tailors, tanners/fur dressers, patternmakers/cutters, electrical fitters/wiremen, telephone/telegraph installers/repairmen, and some glass/pottery/tile workers. Results for lower and upper limbs were significantly correlated but somewhat independent of those found in thorax, the most frequent location. Correlation between head/neck and thorax was moderate. Specific risk excesses were found for rolling mill workers in head/neck, for chimney sweeps in upper limbs, and for aircraft pilots/navigators/flight engineers in lower limbs. Conclusions: High RRs in the trunk among occupations with UV exposure from artificial sources suggest an effect not restricted to exposed sites. An unusual distribution of cases and RRs in chimney sweeps, rolling-mill, or glass/pottery/tile workers suggests local effects of exposures. The not previously reported risk excess in this job and in fur related processes, and the RR in electrical fitters and telephone/telegraph installers deserve further investigation. Disparities between locations, as RRs in thorax and limbs, may reflect differences in aetiological mechanisms. PMID:14739377

  20. Electric field fluctuations in liquid tellurium alloys a hint to bond character

    NARCIS (Netherlands)

    Paulick, C.A.; Brinkmann, R.; Elwenspoek, Michael Curt; von Hartrott, M.; Kiehl, M.; Maxim, P.; Quitmann, D.

    1985-01-01

    Atomic scale electric field fluctuations in liquid tellurium alloys are detected as they induce nuclear spin relaxation rate RQ in noble gas impurity atoms, via quadrupolar interaction. Results for Xe in liquid Ag, Ga, In, Tl, Ge, Sn---Te alloys are discussed, assuming that bonding in these alloys

  1. Hints for Small Disks around Very Low Mass Stars and Brown Dwarfs

    International Nuclear Information System (INIS)

    Hendler, Nathanial P.; Mulders, Gijs D.; Pascucci, Ilaria; Greenwood, Aaron; Kamp, Inga; Henning, Thomas; Ménard, François; Dent, William R. F.; II, Neal J. Evans

    2017-01-01

    The properties of disks around brown dwarfs and very low mass stars (hereafter VLMOs) provide important boundary conditions on the process of planet formation and inform us about the numbers and masses of planets than can form in this regime. We use the Herschel Space Observatory PACS spectrometer to measure the continuum and [O i] 63 μ m line emission toward 11 VLMOs with known disks in the Taurus and Chamaeleon I star-forming regions. We fit radiative transfer models to the spectral energy distributions of these sources. Additionally, we carry out a grid of radiative transfer models run in a regime that connects the luminosity of our sources with brighter T Tauri stars. We find that VLMO disks with sizes 1.3–78 au, smaller than typical T Tauri disks, fit well the spectral energy distributions assuming that disk geometry and dust properties are stellar mass independent. Reducing the disk size increases the disk temperature, and we show that VLMOs do not follow previously derived disk temperature–stellar luminosity relationships if the disk outer radius scales with stellar mass. Only 2 out of 11 sources are detected in [O i] despite a better sensitivity than was achieved for T Tauri stars, suggesting that VLMO disks are underluminous. Using thermochemical models, we show that smaller disks can lead to the unexpected [O i] 63 μ m nondetections in our sample. The disk outer radius is an important factor in determining the gas and dust observables. Hence, spatially resolved observations with ALMA—to establish if and how disk radii scale with stellar mass—should be pursued further.

  2. Riia Oja : "Ruumi lihtsusel on korrastav mõju mõtetele" / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Riia Oja (sünd. 1967) valgustusest kui miljöö loojast, materjalidest, eramu projekteerimisest. Riia Ojast, kes töötab 1991. aastast sisearhitektuuribüroos AS Stuudio Gadis. Ill.: R. Oja värv. portree

  3. Bulk Comptonization: new hints from the luminous blazar 4C+25.05

    Science.gov (United States)

    Kammoun, E. S.; Nardini, E.; Risaliti, G.; Ghisellini, G.; Behar, E.; Celotti, A.

    2018-01-01

    Blazars are often characterized by a spectral break at soft X-rays, whose origin is still debated. While most sources show a flattening, some exhibit a blackbody-like soft excess with temperatures of the order of ∼0.1 keV, similar to low-luminosity, non-jetted Seyferts. Here, we present the analysis of the simultaneous XMM-Newton and NuSTAR observations of the luminous flat-spectrum radio quasar 4C+25.05 (z = 2.368). The observed 0.3-30 keV spectrum is best described by the sum of a hard X-ray power law (Γ = 1.38_{-0.03}^{+0.05}) and a soft component, approximated by a blackbody with kT_BB = 0.66_{-0.04}^{+0.05} keV (rest frame). If the spectrum of 4C+25.05 is interpreted in the context of bulk Comptonization by cold electrons of broad-line region photons emitted in the direction of the jet, such an unusual temperature implies a bulk Lorentz factor of the jet of Γbulk ∼ 11.7. Bulk Comptonization is expected to be ubiquitous on physical grounds, yet no clear signature of it has been found so far, possibly due to its transient nature and the lack of high-quality, broad-band X-ray spectra.

  4. Are You a Gut Responder? Hints on Coping with an Irritable Bowel

    Science.gov (United States)

    ... problems to contend with. These can interfere with work or school and social functions both in obvious and subtle ways – including ... a better understanding of your own gut-brain connections, ask your doctor to suggest a mental health ... Read More Personal Relationships ...

  5. Ignoring Memory Hints: The Stubborn Influence of Environmental Cues on Recognition Memory

    Science.gov (United States)

    Selmeczy, Diana; Dobbins, Ian G.

    2017-01-01

    Recognition judgments can benefit from the use of environmental cues that signal the general likelihood of encountering familiar versus unfamiliar stimuli. While incorporating such cues is often adaptive, there are circumstances (e.g., eyewitness testimony) in which observers should fully ignore environmental cues in order to preserve memory…

  6. Hints About Some Baseful but Indispensable Elements in Speech Recognition and Reconstruction

    Directory of Open Access Journals (Sweden)

    Mihaela Costin

    2002-07-01

    Full Text Available The cochlear implant (CI is a device used to reconstruct the hearing capabilities of a person diagnosed with total cophosis. This impairment may occur after some accidents, chemotherapy etc., the person still having an intact hearing nerve. The cochlear implant has two parts: a programmable, external part, the Digital Signal Processing (DSP device which process and transform the speech signal, and another surgically implanted part, with a certain number of electrodes (depending on brand used to stimulate the hearing nerve. The speech signal is fully processed in the DSP external device resulting the ``coded'' information on speech. This is modulated with the support of the fundamental frequency F0 and the energy impulses are inductively sent to the hearing nerve. The correct detection of this frequency is very important, determining the manner of hearing and making the difference between a "computer'' voice and a natural one. The results are applicable not only in the medical domain, but also in the Romanian speech synthesis.

  7. The new elastic scattering measurements of TOTEM -Are there hints for asymptotics?

    Science.gov (United States)

    Troshin, Sergey M.; Tyurin, Nikolai E.

    2017-03-01

    We point out to another indication of the black-disk limit exceeding in hadron interactions found in the recent impact parameter analysis performed by the TOTEM Collaboration at √{s}=8 TeV and emphasize that this observation might be interpreted as a confirmation of the reflective scattering mode appearance at the LHC energies.

  8. Andro Kööp : "Püüan ruumi tunnet maalida" / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Andro Kööp (sünd. 1967) sellest, kuidas ta sattus sisearhitektuuriga tegelema, oma eelistustest ja harmooniast sisekujunduses, kodu kujundusest jm. A. Kööbist, tema loomingust, omistatud preemiad, valik A. Kööbi kujundatud ühiskondlikke interjööre. Ill.: värv. foto A. Kööbist

  9. Mati Hint - sünge keeleteadlane ja pessimistlik ühiskonnategelane / Mari Klein

    Index Scriptorium Estoniae

    Klein, Mari, 1979-

    2007-01-01

    11. septembril peeti Tallinna Ülikoolis seminari, mis oli pühendatud Mati Hindi 70. sünnipäevale. Ettekannetega esinesid ülikoolikaaslased, sõbrad ja kolleegid Rein Veidemann, Haldur Õim, Martin Ehala, Mats Traat, Tapani Lehtinen, Jaan Kaplinski

  10. Suurimad toetajad külas / Toivo Olvi

    Index Scriptorium Estoniae

    Olvi, Toivo

    2003-01-01

    11. VII külastasid Inju lastekodu mõisa ehitaja ja omaniku Hermann von Krause järeltulijad. Wolfgang ja Riccarda von Mecklenburg toetasid tänavu lastekodu renoveerimist 10000 euroga. Lühtri ostmiseks annetas raha Mati Hint. Lastekodu finantseerimisest

  11. Shiftwork Scheduling for the 1990s.

    Science.gov (United States)

    Coleman, Richard M.

    1989-01-01

    The author discusses the problems of scheduling shift work, touching on such topics as employee desires, health requirements, and business needs. He presents a method for developing shift schedules that addresses these three areas. Implementation hints are also provided. (CH)

  12. Case Report HeLs malnourished o admit him to the nutrition unit ...

    African Journals Online (AJOL)

    and vocal resonance on the left side, anterior and posterior, with reduced breath ... hint that she may have been the source of the child's HIV infection, before, during or ... child's HIV status? Has either of them been on anti-retroviral therapy?

  13. SPSS for starters

    CERN Document Server

    Cleophas, Ton J

    2010-01-01

    This book contains all statistical tests relevant for starters on SPSS. Each test is explained using a data example from clinical practice along with the main tables of results with an accompanying text with interpretations of the results and hints.

  14. Whale Watching in the Gulf of Maine.

    Science.gov (United States)

    Carkin, Clayton A.

    1985-01-01

    Describes a variety of teaching strategies to prepare a class for a whale watching field trip. Guidelines for recording a sighting, pictures and statistics for commonly and/or occasionally seen whales, and hints for avoiding sea sickness are included. (DH)

  15. Careers in Online: Want Ads in the Online Industry.

    Science.gov (United States)

    Dolan, Donna R.; Hoffman, Laura J.

    1984-01-01

    Describes sources of job listings in online industry including "New York Times,""Boston Globe,""Washington Post,""Los Angeles Times,""Wall Street Journal,""National Business Employment Weekly," and hints on methods for reading and responding to ads and placing them. Sample advertisements…

  16. Pulsed magnetic fields and their assessment according to the accident prevention regulation BGV B11; Gepulste magnetische Felder und Ihre Bewertung nach der Unfallverhuetungsvorschrift BGV B11

    Energy Technology Data Exchange (ETDEWEB)

    Heinrich, H. [2h-engineering, Hausen (Germany)

    2004-07-01

    The accident prevention regulation BGV B11 - Electromagnetic Fields - contains a method for the assessment of pulsed fields. This paper gives valuable hints and background information and presents a new tool for the computer-based assessment of these fields. (orig.)

  17. Communicating with the Public: Getting It into Print.

    Science.gov (United States)

    Dyal, Donald

    1988-01-01

    Discusses the advantages for libraries of utilizing print media for public information and public relations. News releases, interest stories, and feature stories are described, and hints on writing style for each format and on getting items printed are offered. (MES)

  18. Virtual environment to quantify the influence of colour stimuli on the performance of tasks requiring attention.

    Science.gov (United States)

    Silva, Alessandro P; Frère, Annie F

    2011-08-19

    Recent studies indicate that the blue-yellow colour discrimination is impaired in ADHD individuals. However, the relationship between colour and performance has not been investigated. This paper describes the development and the testing of a virtual environment that is capable to quantify the influence of red-green versus blue-yellow colour stimuli on the performance of people in a fun and interactive way, being appropriate for the target audience. An interactive computer game based on virtual reality was developed to evaluate the performance of the players.The game's storyline was based on the story of an old pirate who runs across islands and dangerous seas in search of a lost treasure. Within the game, the player must find and interpret the hints scattered in different scenarios. Two versions of this game were implemented. In the first, hints and information boards were painted using red and green colours. In the second version, these objects were painted using blue and yellow colours. For modelling, texturing, and animating virtual characters and objects the three-dimensional computer graphics tool Blender 3D was used. The textures were created with the GIMP editor to provide visual effects increasing the realism and immersion of the players. The games were tested on 20 non-ADHD volunteers who were divided into two subgroups (A1 and A2) and 20 volunteers with ADHD who were divided into subgroups B1 and B2. Subgroups A1 and B1 used the first version of the game with the hints painted in green-red colors, and subgroups A2 and B2 the second version using the same hints now painted in blue-yellow. The time spent to complete each task of the game was measured. Data analyzed with ANOVA two-way and posthoc TUKEY LSD showed that the use of blue/yellow instead of green/red colors decreased the game performance of all participants. However, a greater decrease in performance could be observed with ADHD participants where tasks, that require attention, were most affected

  19. World Radio and TV Handbook. A Complete Directory of International Radio and Television. Twenty-Seventh Edition. 1973.

    Science.gov (United States)

    Frost, J. M., Ed.

    This handbook provides detailed information about broadcasting and international broadcasting organization. It lists Esperanto programs, English language news programs from foreign countries, religious broadcasting organizations, and gives hints to improve broadcast reception. The main entry section gives a detailed description of radio stations…

  20. BOOK REVIEWS BOEKRESE SIES

    African Journals Online (AJOL)

    under consideration, and tbe error simply annoys the medical reader. There is a hint of .... In the last analysis what both doctor and patient want to know is the diagnosis ... is the armour of education adequate to arouse curiosity in the common ...

  1. Fulltext PDF

    Indian Academy of Sciences (India)

    2National Centre for Radio Astrophysics, Tata Institute of Fundamental Research, ... high-redshift—cosmology: miscellaneous—elementary particles. .... may provide a hint about its origin. ..... Within conventional physics the corrections to ... One interesting possibility is the presence of a very low mass background pseudo-.

  2. Star-Triangle Relation of the Chiral Potts Model Revisited

    OpenAIRE

    Horibe, M.; Shigemoto, K.

    2001-01-01

    We give the simple proof of the star-triangle relation of the chiral Potts model. We also give the constructive way to understand the star-triangle relation of the chiral Potts model, which may give the hint to give the new integrable models.

  3. Gamification for low-literates: findings on motivation, user experience, and study design

    NARCIS (Netherlands)

    Schouten, D.G.M.; Pfab, I.; Cremers, A.H.M.; Dijk, B. van; Neerincx, M.A.

    2014-01-01

    This study investigated the effects of the gamification elements of scaffolding, score and hints on the user enjoyment and motivation of people of low literacy. In a four-condition within-subjects experiment, participants per-formed mental spatial ability tests with the aforementioned elements.

  4. The Peroxisome Proliferator-Activated Receptor α is dispensable for cold-induced adipose tissue browning in mice

    NARCIS (Netherlands)

    Defour, Merel; Dijk, Wieneke; Ruppert, Philip; Nascimento, Emmani B.M.; Schrauwen, Patrick; Kersten, Sander

    2018-01-01

    Objective: Chronic cold exposure causes white adipose tissue (WAT) to adopt features of brown adipose tissue (BAT), a process known as browning. Previous studies have hinted at a possible role for the transcription factor Peroxisome Proliferator-Activated Receptor alpha (PPARα) in cold-induced

  5. Gamification for low-literates: Findings on motivation, user experience, and study design

    NARCIS (Netherlands)

    Schouten, Dylan; Pfab, Isabel; Cremers, Anita; van Dijk, Elisabeth M.A.G.; Neerincx, Mark; Miesenberger, Klaus; Fels, Deborah; Archambault, Dominique; Penaz, Petr; Zagler, Wolfgang

    This study investigated the effects of the gamification elements of scaffolding, score and hints on the user enjoyment and motivation of people of low literacy. In a four-condition within-subjects experiment, participants performed mental spatial ability tests with the aforementioned elements.

  6. Fermentation: From Sensory Experience to Conceptual Understanding

    Science.gov (United States)

    Moore, Eugene B.

    1977-01-01

    Presented is a laboratory exercise that utilizes the natural yeast carbonation method of making homemade root beer to study fermentation and the effect of variables upon the fermentation process. There are photographs, a sample data sheet, and procedural hints included. (Author/MA)

  7. User Interface Design for Dynamic Geometry Software

    Science.gov (United States)

    Kortenkamp, Ulrich; Dohrmann, Christian

    2010-01-01

    In this article we describe long-standing user interface issues with Dynamic Geometry Software and common approaches to address them. We describe first prototypes of multi-touch-capable DGS. We also give some hints on the educational benefits of proper user interface design.

  8. 7th high energy heavy ion study

    International Nuclear Information System (INIS)

    Bock, R.; Gutbrod, H.H.; Stock, R.

    1985-03-01

    These proceedings contain the articles presented at the named conference. They deal with relativistic heavy ion reactions, the expansion and freeze-out of nuclear matter, anomalon experiments, and multifragmentation and particle correlations in heavy ion reactions. See hints under the relevant topics. (HSI)

  9. Synergy of a warm spring and dry summer

    Science.gov (United States)

    Yude Pan; David. Schimel

    2016-01-01

    An analysis suggests that high carbon uptake by US land ecosystems during the warm spring of 2012 offset the carbon loss that resulted from severe drought over the summer — and hints that the warm spring could have worsened the drought.

  10. Schoenfeld's problem solving theory in a student controlled learning environment

    NARCIS (Netherlands)

    Harskamp, E.; Suhre, C.

    2007-01-01

    This paper evaluates the effectiveness of a student controlled computer program for high school mathematics based on instruction principles derived from Schoenfeld's theory of problem solving. The computer program allows students to choose problems and to make use of hints during different episodes

  11. Approximating methods for intractable probabilistic models: Applications in neuroscience

    DEFF Research Database (Denmark)

    Højen-Sørensen, Pedro

    2002-01-01

    This thesis investigates various methods for carrying out approximate inference in intractable probabilistic models. By capturing the relationships between random variables, the framework of graphical models hints at which sets of random variables pose a problem to the inferential step. The appro...

  12. Operation Savannah: A Measure of SADF Decline, Resourcefulness ...

    African Journals Online (AJOL)

    Authorised amidst debilitating secrecy by a miscalculating South African government, Savannah demonstrated significant South African military equipment inadequacies, particularly in terms of artillery, armour and the need for an infantry combat vehicle. Savannah also gave hints of SADF strength residing in the ...

  13. Electroweak couplings of the lepton

    Indian Academy of Sciences (India)

    magnetic and electric dipole moments of the tau have been performed. ... pressing issue in particle physics today, a truly satisfactory theory of mass should be ex- .... structure of the universe, and may well turn out to be a valuable hint in our ...

  14. Kernforschungsanlage Juelich, Institut fuer Kernphysik: Annual report 1983

    International Nuclear Information System (INIS)

    Baur, G.; Mayer-Boericke, C.; Schult, O.; Seyfarth, H.; Speth, J.; Turek, P.

    1984-04-01

    This annual report contains extended abstracts of the work performed at the named institute together with a list of publications. The abstracts deal with nuclear reactions, nuclear spectroscopy, atomic collisions, solar energy, and technical developments. See hints under the relevant topics. (HSI) [de

  15. Res Publica v respublike / Roman Gornev

    Index Scriptorium Estoniae

    Gornev, Roman

    2002-01-01

    Järg 29. november nr. 48 lk. 7. Res Publica - uue poliitika partei. Res Publica Ida-Virumaal, partei juhtfiguurid, Res Publica Kohtla-Järvel. Koalitsioonileping Keskerakonnaga viis konfliktini partei juhtkonnaga. Kohtla-Järve Res Publica kohaliku organisatsiooni konflikti partei juhtkonnaga kommenteerib Hants Hint

  16. The Danish hearing in noise test

    DEFF Research Database (Denmark)

    Nielsen, Jens Bo; Dau, Torsten

    2010-01-01

    Objective : A Danish version of the hearing in noise test (HINT) has been developed and evaluated in normal-hearing (NH) and hearing-impaired (HI) listeners. The speech material originated from Nielsen & Dau (2009) where a sentence-based intelligibility equalization method was presented. Design...

  17. Differences in technology transfer between science-based and development-based industries : transfer mechanisms and barriers

    NARCIS (Netherlands)

    Gilsing, V.A.; Bekkers, R.N.A.; Bodas Freitas, I.M.; Steen, van der M.

    2011-01-01

    Although several studies in the wide body of literature on technology transfer have hinted at differences across industries, this still remains an understudied issue. Our study addresses this topic and considers to what degree technology transfer processes differ across different industrial sectors.

  18. The filler-rubber interface in styrene butadiene nanocomposites with anisotropic silica particles: morphology and dynamic properties

    Czech Academy of Sciences Publication Activity Database

    Tadiello, L.; D´Arienzo, M.; Di Credico, B.; Hanel, T.; Matějka, Libor; Mauri, M.; Morazzoni, F.; Simonutti, R.; Špírková, Milena; Scotti, R.

    2015-01-01

    Roč. 11, č. 20 (2015), s. 4022-4033 ISSN 1744-683X Grant - others:European Commission(XE) COST Action MP1202 HINT Institutional support: RVO:61389013 Keywords : nanocomposites * silica particles * polymer Subject RIV: CD - Macromolecular Chemistry Impact factor: 3.798, year: 2015

  19. Probing dark matter annihilation in the Galaxy with antiprotons and gamma rays

    Energy Technology Data Exchange (ETDEWEB)

    Cuoco, Alessandro; Heisig, Jan; Korsmeier, Michael; Krämer, Michael, E-mail: cuoco@physik.rwth-aachen.de, E-mail: heisig@physik.rwth-aachen.de, E-mail: korsmeier@physik.rwth-aachen.de, E-mail: mkraemer@physik.rwth-aachen.de [Institute for Theoretical Particle Physics and Cosmology, RWTH Aachen University, 52056 Aachen (Germany)

    2017-10-01

    A possible hint of dark matter annihilation has been found in Cuoco, Korsmeier and Krämer (2017) from an analysis of recent cosmic-ray antiproton data from AMS-02 and taking into account cosmic-ray propagation uncertainties by fitting at the same time dark matter and propagation parameters. Here, we extend this analysis to a wider class of annihilation channels. We find consistent hints of a dark matter signal with an annihilation cross-section close to the thermal value and with masses in range between 40 and 130 GeV depending on the annihilation channel. Furthermore, we investigate in how far the possible signal is compatible with the Galactic center gamma-ray excess and recent observation of dwarf satellite galaxies by performing a joint global fit including uncertainties in the dark matter density profile. As an example, we interpret our results in the framework of the Higgs portal model.

  20. Evaluation of neuromotor development by means of the Harris Infant Neuromotor Test

    Directory of Open Access Journals (Sweden)

    Márcia Maria Coelho Oliveira Lopes

    2014-08-01

    Full Text Available Objective: To investigate the neuromotor development of at-risk children between three and 12 months of life, administering the Brazilian version of the Harris Infant Neuromotor Test (HINT.Method: A longitudinal study, with 78 children and 76 parents/guardians discharged from a neonatal intensive care unit in Fortaleza-CE/Brazil. Two instruments were administered: HINT and a socioeconomic questionnaire, between July/2009 to August/2010. Data from 55 preterm and 23 term children were analyzed. Results: The final mean scores ranged from 14.6 to 25.2 and from 11.2 to 24.7, for preterm and term, respectively, showing that 91% of children demonstrated good neuromotor performance; seven premature infants showed alterations which led to the referral of three children to a specialized clinic for examination and diagnostics.Conclusion: The test allowed nurses to assess infant development, identify deviations early, and plan interventions.

  1. Zone routing in a torus network

    Science.gov (United States)

    Chen, Dong; Heidelberger, Philip; Kumar, Sameer

    2013-01-29

    A system for routing data in a network comprising a network logic device at a sending node for determining a path between the sending node and a receiving node, wherein the network logic device sets one or more selection bits and one or more hint bits within the data packet, a control register for storing one or more masks, wherein the network logic device uses the one or more selection bits to select a mask from the control register and the network logic device applies the selected mask to the hint bits to restrict routing of the data packet to one or more routing directions for the data packet within the network and selects one of the restricted routing directions from the one or more routing directions and sends the data packet along a link in the selected routing direction toward the receiving node.

  2. Are all modes created equal? An analysis of the WMAP 5- and 7-year data without inflationary prejudice

    International Nuclear Information System (INIS)

    Gjerloew, Eirik; Elgaroey, Oystein

    2011-01-01

    We submit recent claims of hints of primordial tensor perturbations and a scale-dependent spectral index in the WMAP data to a closer scrutiny. Our approach differs in that we use different best-fit values at which to fix the parameters not to be varied, and in that we use CosmoMC, thus incorporating the WMAP likelihood code and EE and BB mode data. We introduce a new parameter to test the claims of a scale-dependent spectral index. While we do find some hints of a scale-dependent spectral index over the multipole range l=2-220, the change in maximum likelihood is too small to justify introducing a new parameter. We conclude that there is no significant detection of primordial tensor perturbations, and that the assumption of a scale-independent spectral index in this multipole range has little effect on the amount of primordial gravitational waves found.

  3. Searching for New Physics with b→sτ^{+}τ^{-} Processes.

    Science.gov (United States)

    Capdevila, Bernat; Crivellin, Andreas; Descotes-Genon, Sébastien; Hofer, Lars; Matias, Joaquim

    2018-05-04

    In recent years, intriguing hints for the violation of lepton flavor universality (LFU) have been accumulated in semileptonic B decays, both in the charged-current transitions b→cℓ^{-}ν[over ¯]_{ℓ} (i.e., R_{D}, R_{D^{*}}, and R_{J/ψ}) and the neutral-current transitions b→sℓ^{+}ℓ^{-} (i.e., R_{K} and R_{K^{*}}). Hints for LFU violation in R_{D^{(*)}} and R_{J/ψ} point at large deviations from the standard model (SM) in processes involving tau leptons. Moreover, LHCb has reported deviations from the SM expectations in b→sμ^{+}μ^{-} processes as well as in the ratios R_{K} and R_{K^{*}}, which together point at new physics (NP) affecting muons with a high significance. These hints for NP suggest the possibility of huge LFU-violating effects in b→sτ^{+}τ^{-} transitions. In this Letter, we predict the branching ratios of B→Kτ^{+}τ^{-}, B→K^{*}τ^{+}τ^{-}, and B_{s}→ϕτ^{+}τ^{-}, taking into account NP effects in the Wilson coefficients C_{9(^{'})}^{ττ} and C_{10(^{'})}^{ττ}. Assuming a common NP explanation of R_{D}, R_{D^{(*)}}, and R_{J/ψ}, we show that a very large enhancement of b→sτ^{+}τ^{-} processes, of around 3 orders of magnitude compared to the SM, can be expected under fairly general assumptions. We find that the branching ratios of B_{s}→τ^{+}τ^{-}, B_{s}→ϕτ^{+}τ^{-}, and B→K^{(*)}τ^{+}τ^{-} under these assumptions are in the observable range for LHCb and Belle II.

  4. Comparative Impacts of Scala Vestibuli Versus Scala Tympani Cochlear Implantation on Auditory Performances and Programming Parameters in Partially Ossified Cochleae.

    Science.gov (United States)

    Trudel, Mathieu; Côté, Mathieu; Philippon, Daniel; Simonyan, David; Villemure-Poliquin, Noémie; Bussières, Richard

    2018-07-01

    To compare scala vestibuli versus scala tympani cochlear implantation in terms of postoperative auditory performances and programming parameters in patients with severe scala tympani ossification. Retrospective case-control study. Tertiary referral center. One hundred three pediatric and adult patients who underwent cochlear implant surgery between 2000 and 2016. Three groups were formed: a scala vestibuli group, a scala tympani with ossification group, and a scala tympani without ossification group. Patients were matched based on their age, sex, duration of deafness, and side of implantation (ratio of 1:2:2). Postoperative evaluation of auditory performances and programming parameters following intensive functional rehabilitation program completion. Multimedia adaptive test (MAT), hearing in noise test (HINT SNR +10 dB, HINT SNR +5 dB, and HINT SNR +0 dB), impedances, neural response telemetry thresholds (NRT), neural response imaging thresholds (NRI), comfortable levels (C-levels), and threshold levels (T-levels) were compared between groups. Twenty-one patients underwent scala vestibuli cochlear implantation: 19 adults and two children. Auditory performances were similar between groups, although sentence recognition in a noisy environment was slightly higher in the scala vestibuli group. Impedance values were also higher in the scala vestibuli group, but all other programming parameters were similar between groups. We present the largest series of patients with scala vestibuli cochlear implantation. This approach provides at least comparable auditory performances without having any deleterious effects on programming parameters. This viable and useful insertion route might be the primary surgical alternative when facing partial cochlear ossification.

  5. Searching for New Physics with b →s τ+τ- Processes

    Science.gov (United States)

    Capdevila, Bernat; Crivellin, Andreas; Descotes-Genon, Sébastien; Hofer, Lars; Matias, Joaquim

    2018-05-01

    In recent years, intriguing hints for the violation of lepton flavor universality (LFU) have been accumulated in semileptonic B decays, both in the charged-current transitions b →c ℓ-ν¯ℓ(i.e., RD, RD*,and RJ /ψ) and the neutral-current transitions b →s ℓ+ℓ-(i.e., RK and RK*). Hints for LFU violation in RD(*) and RJ /ψ point at large deviations from the standard model (SM) in processes involving tau leptons. Moreover, LHCb has reported deviations from the SM expectations in b →s μ+μ- processes as well as in the ratios RK and RK*, which together point at new physics (NP) affecting muons with a high significance. These hints for NP suggest the possibility of huge LFU-violating effects in b →s τ+τ- transitions. In this Letter, we predict the branching ratios of B →K τ+τ-, B →K*τ+τ-, and Bs→ϕ τ+τ-, taking into account NP effects in the Wilson coefficients C9(') ττ and C10(') τ τ. Assuming a common NP explanation of RD , RD(*), and RJ /ψ, we show that a very large enhancement of b →s τ+τ- processes, of around 3 orders of magnitude compared to the SM, can be expected under fairly general assumptions. We find that the branching ratios of Bs→τ+τ-, Bs→ϕ τ+τ-, and B →K(*)τ+τ- under these assumptions are in the observable range for LHCb and Belle II.

  6. On the role of doping in High-Tc superconductors

    International Nuclear Information System (INIS)

    Mei, C.; Smith, V.H. Jr.

    1994-01-01

    High-T c superconductors (HTSCS) are usually obtained by doping electron donors or acceptors into parent materials. The actual role played by doping is still uncertain with various interpretations. The present electronic structure study provides some hints which may help to solve the mystery

  7. Heating with wood. An advisor for a correct and clean heating; Heizen mit Holz. Ein Ratgeber zum richtigen und sauberen Heizen

    Energy Technology Data Exchange (ETDEWEB)

    Behnke, Anja [Umweltbundesamt, Dessau (Germany); Kemper, Bernd-Michael [Landesanstalt fuer Umwelt, Messungen und Naturschutz Baden-Wuerttemberg (LUBW), Karlsruhe (Germany)

    2010-02-15

    Correctly used, wood is an environmental-friendly fuel. With well prepared wood, the wood furnace or wood boiler provides for comfortable warmth and does not load the environment too much. The brochure under consideration gives hints, how a wood heating is to be operated correctly.

  8. Ask-Elle: an adaptable programming tutor for Haskell giving automated feedback

    NARCIS (Netherlands)

    Gerdes, Alex; Heeren, Bastiaan; Jeuring, J.T.; Binsbergen, Thomas van

    2015-01-01

    Ask-Elle is a tutor for learning the higher-order, strongly-typed functional programming language Haskell. It supports the stepwise development of Haskell programs by verifying the correctness of incomplete programs, and by providing hints. Programming exercises are added to Ask-Elle by providing a

  9. Ask-Elle: an Adaptable Programming Tutor for Haskell Giving Automated Feedback

    NARCIS (Netherlands)

    Gerdes, A.; Heeren, B.J.; Jeuring, J.T.; Binsbergen, Thomas~van

    2017-01-01

    Ask-Elle is a tutor for learning the higher-order, strongly-typed functional programming language Haskell. It supports the stepwise development of Haskell programs by verifying the correctness of incomplete programs, and by providing hints. Programming exercises are added to Ask-Elle by providing a

  10. Shoptalk: A Column of Brief Ideas and Sundry Thoughts about Media and Teaching English.

    Science.gov (United States)

    Donelson, Kenneth L., Ed.

    1970-01-01

    Practical advice is provided by Arizona high School English teachers on such areas of media usage as lettering for media projects, hints on movie-making, uses for instamatic cameras and slides, and the use of media for units on propaganda, oral communication, and composition. (MF)

  11. The role of individual differences on the effect of synchronous coaching of trainee teachers in plenary situations

    NARCIS (Netherlands)

    Hooreman, Ralph W.; Kommers, Petrus A.M.; Jochems, Wim M.G.

    2008-01-01

    Historically, synchronous (direct) coaching is an addition to the traditional asynchronous (indirect) supervision of trainee teachers. The new trainee receives concrete hints on “how to proceed further” via an earpiece. In this study the role of personality traits and the orientation of learning to

  12. Essential calculus with applications

    CERN Document Server

    Silverman, Richard A

    1989-01-01

    Rigorous but accessible text introduces undergraduate-level students to necessary background math, then clear coverage of differential calculus, differentiation as a tool, integral calculus, integration as a tool, and functions of several variables. Numerous problems and a supplementary section of ""Hints and Answers."" 1977 edition.

  13. High energy physics and nuclear structure

    International Nuclear Information System (INIS)

    Measday, D.F.; Thomas, A.W.

    1980-01-01

    These proceedings contain the papers presented at the named conference. These concern eletromagnetic interactions, weak interactions, strong interactions at intermediate energy, pion reactions, proton reactions, strong interactions at high energy, as well as new facilities and applications. See hints under the relevant topics. (HSI)

  14. "Mu Armas..." = "My Dear..." / Hedi Rosma

    Index Scriptorium Estoniae

    Rosma, Hedi, 1983-

    2016-01-01

    Ringkäik Tallinna Kunstihoones Marge Monko kuraatorinäitusel "Kõik kirjad on armastuskirjad", kus kunstnikud Eestist, Belgiast, Iirimaalt, Saksamaalt ja Singapurist uurivad, mis on saanud romantilisest kirest ihade kiire rahuldamise ajastul. Eestit esindavad Anna-Stina Treumund, Anu Põder, Minna Hint ja Johnson & Johnson

  15. Virginia Tech researchers find tiny bubbles a storehouse of knowledge

    OpenAIRE

    Trulove, Susan

    2005-01-01

    Fluid inclusions -- tiny bubbles of fluid or vapor trapped inside rock as it forms-- are clues to the location of ores and even petroleum; and they are time capsules that contain insights on the power of volcanos and hints of life in the universe.

  16. Einstein Gravity Explorer–a medium-class fundamental physics mission

    NARCIS (Netherlands)

    Schiller, S.; Tino, G.M.; Gill, E.

    2008-01-01

    The Einstein Gravity Explorer mission (EGE) is devoted to a precise measurement of the properties of space-time using atomic clocks. It tests one of the most fundamental predictions of Einstein’s Theory of General Relativity, the gravitational redshift, and thereby searches for hints of quantum

  17. Do micro brown dwarf detections explain the galactic dark matter?

    NARCIS (Netherlands)

    Nieuwenhuizen, T.M.; Schild, R.E; Gibson, C.H.

    2011-01-01

    The baryonic dark matter dominating the structures of galaxies is widely considered as mysterious, but hints for it have been in fact detected in several astronomical observations at optical, infrared, and radio wavelengths. We call attention to the pattern of star formation in a galaxy merger, the

  18. International conference on fifty years research in nuclear fission

    International Nuclear Information System (INIS)

    1989-02-01

    These proceedings contain extended abstracts of the papers presented at the named conference. They deal with static properties of fission, instrumentation for fission studies, fission in compound-nucleus reactions, fission dynamics, fission-like heavy ion reactions, and fusion reactions. See hints under the relevant topics. (HSI)

  19. α-Monitor(roating drum cell) - an in-line instrument for continuous measuring α-activity

    International Nuclear Information System (INIS)

    Groll, P.; Brenk, O.; Guettle, G.; Persohn, M.; Radek, S.; Roeder, L.; Roemer, J.

    1982-03-01

    In this report the documentation for the installation of the α-monitor in a reprocessing facility is given. The mechanics of the apparatus is described as well as the electronics. In detail the conditions for normal operation and hints for trouble-shooting are given. (orig.) [de

  20. Linear response theory applied to the computation of multi-differential cross sections in deep inelastic reactions

    International Nuclear Information System (INIS)

    Ngo, C.

    1978-01-01

    Correlations between observable quantities in deep inelastic reactions, which are observed through multidifferential cross sections measurements, provide a severe test for the models by making strong constraints. Nevertheless these multicorrelated measurements provide hints for the physical features which they have to take into account. (orig.) [de

  1. High grade serous ovarian carcinoma with serous tubal intraepithelial carcinoma in a case presented with atypical glandular cell favor neoplasm cervical cytology and dermatomyositis

    Directory of Open Access Journals (Sweden)

    Mun-Kun Hong

    2015-04-01

    Conclusion: The patient had serous carcinoma of the ovary with tubal STIC, which presented as dermatomyositis. The AGC-FN identified from a Pap smear hinted at a diagnosis of ovarian carcinoma. These presentations point to an occult malignancy in the genital tract and demand careful diagnostic workup.

  2. GSI-contributions to HCI-92

    International Nuclear Information System (INIS)

    1992-11-01

    This preprint comprises all the papers presented at the VIth International Conference on the Physics of Highly Charged Ions (Manhattan, Kansas, September 28 - October 2, 1992) reporting on results from experiments performed at the GSI heavy ion accelerator facilities. See hints under the relevant topics. (orig./HSI)

  3. Peace in the year 2000. Frieden 2000. Fragen nach Sicherheit und Glauben

    Energy Technology Data Exchange (ETDEWEB)

    Gollwitzer, H.

    1982-01-01

    The author appeals to theology in general to take up responsibility for the fate of mankind, and he does so in a manner full of fantasy, encouraging people to become politically active. This book is manual full of standfast and thoughtful hints for pedagogics in peace.

  4. On the key role of SiO2@POSS hybrid filler in tailoring networking and interfaces in rubber nanocomposites

    Czech Academy of Sciences Publication Activity Database

    Redaelli, M.; D´Arienzo, M.; Brus, Jiří; Di Credico, B.; Geppi, M.; Giannini, L.; Matějka, Libor; Martini, F.; Panattoni, F.; Špírková, Milena; Šlouf, Miroslav; Scotti, R.; Morazzoni, F.

    2018-01-01

    Roč. 65, February (2018), s. 429-439 ISSN 0142-9418 Grant - others:European Commission(XE) COST Action MP1202 HINT Institutional support: RVO:61389013 Keywords : rubber nanocomposites * hybrid materials * POSS Subject RIV: CD - Macromolecular Chemistry OBOR OECD: Polymer science Impact factor: 2.464, year: 2016

  5. Role of Working Memory and Strategy-Use in Feedback Effects on Children's Progression in Analogy Solving:an Explanatory Item Response Theory Account

    Science.gov (United States)

    Stevenson, Claire E.

    2017-01-01

    This study contrasted the effects of tutoring, multiple try and no feedback on children's progression in analogy solving and examined individual differences herein. Feedback that includes additional hints or explanations leads to the greatest learning gains in adults. However, children process feedback differently from adults and effective…

  6. e+e- collisions at 500 GeV: The physics potential

    International Nuclear Information System (INIS)

    Zerwas, P.M.

    1992-08-01

    This report is the second part of the proceedings, which contain the articles presented at the named workshop. The articles in these proceedings concern extended gauge models; supersymmetry; alternative particle models; as well as beamstrahlung and photon-photon interactions. See hints under the relevant topics. (HSI)

  7. Web Search Engines

    OpenAIRE

    Rajashekar, TB

    1998-01-01

    The World Wide Web is emerging as an all-in-one information source. Tools for searching Web-based information include search engines, subject directories and meta search tools. We take a look at key features of these tools and suggest practical hints for effective Web searching.

  8. 3D protein-structure-oriented discovery of clinical relation across chronic lymphocytic leukemia patients

    DEFF Research Database (Denmark)

    Mochament, Konstantinos; Agathangelidis, Andreas; Polychronidou, Eleftheria

    2017-01-01

    Chronic lymphocytic leukemia (CLL) is the most common adult leukemia with still unclear etiology. Indications of antigenic pressure have been hinted, using sequence and structure-based reasoning. The accuracy of such approaches, and in particular of the ones derived from 3D models obtained from t...

  9. Gauge theory and gravitation

    International Nuclear Information System (INIS)

    Kikkawa, Keiji; Nakanishi, Noboru; Nariai, Hidekazu

    1983-01-01

    These proceedings contain the articles presented at the named symposium. They deal with geometrical aspects of gauge theory and gravitation, special problems in gauge theories, quantum field theory in curved space-time, quantum gravity, supersymmetry including supergravity, and grand unification. See hints under the relevant topics. (HSI)

  10. Guinea Pigs: Versatile Animals for the Classroom

    Science.gov (United States)

    Barman, Charles R.

    1977-01-01

    Guinea pigs are presented as versatile classroom animals. Suggestions for animal behavior and genetics studies are given. Also included is information concerning sex determination and the breeding of guinea pigs, and hints on keeping these animals in the classroom. References and illustrations complete the article. (MA)

  11. The Role of Culture on Knowledge Transfer: The Case of the Multinational Corporation

    Science.gov (United States)

    Lucas, Leyland M.

    2006-01-01

    Purpose: This paper aims to look at the issue of culture's role in knowledge transfer within multinational corporations (MNCs). Studies of MNCs have hinted at the importance of culture to the performance of subsidiaries. Using Hofstede's cultural dimensions of power distance, individualism/collectivism, uncertainty avoidance, and…

  12. Alterations in theory of mind in patients with schizophrenia and non-psychotic relatives.

    Science.gov (United States)

    Janssen, I; Krabbendam, L; Jolles, J; van Os, Jim

    2003-08-01

    It has been proposed that alterations in theory of mind underlie specific symptoms of psychosis. The present study examined whether alterations in theory of mind reflect a trait that can be detected in non-psychotic relatives of patients with schizophrenia. Participants were 43 patients with schizophrenia or schizoaffective disorder, 41 first-degree non-psychotic relatives and 43 controls from the general population. Theory of mind was assessed using a hinting task and a false-belief task. There was a significant association between schizophrenia risk and failure on the hinting task (OR linear trend = 2.01, 95% CI: 1.22-3.31), with relatives having intermediate values between patients and controls. Adjustment for IQ and neuropsychological factors reduced the association by small amounts. The association between schizophrenia risk and failure on the false-belief tasks was not significant. Changes in theory of mind are associated with schizophrenia liability. General cognitive ability and neuropsychological measures seem to mediate only part of this association.

  13. The performance of an automatic acoustic-based program classifier compared to hearing aid users' manual selection of listening programs.

    Science.gov (United States)

    Searchfield, Grant D; Linford, Tania; Kobayashi, Kei; Crowhen, David; Latzel, Matthias

    2018-03-01

    To compare preference for and performance of manually selected programmes to an automatic sound classifier, the Phonak AutoSense OS. A single blind repeated measures study. Participants were fit with Phonak Virto V90 ITE aids; preferences for different listening programmes were compared across four different sound scenarios (speech in: quiet, noise, loud noise and a car). Following a 4-week trial preferences were reassessed and the users preferred programme was compared to the automatic classifier for sound quality and hearing in noise (HINT test) using a 12 loudspeaker array. Twenty-five participants with symmetrical moderate-severe sensorineural hearing loss. Participant preferences of manual programme for scenarios varied considerably between and within sessions. A HINT Speech Reception Threshold (SRT) advantage was observed for the automatic classifier over participant's manual selection for speech in quiet, loud noise and car noise. Sound quality ratings were similar for both manual and automatic selections. The use of a sound classifier is a viable alternative to manual programme selection.

  14. 4. topical workshop on proton-antiproton collider physics

    International Nuclear Information System (INIS)

    Haenni, H.; Schacher, J.

    1984-01-01

    The most exciting topic at this Workshop was clearly the experimental hint for new unexpected phenomena, reported by the UA1 and UA2 Collaborations: At the CERN SPS Collider (vs = 540 GeV), a few events were observed with high missing transverse energy in association with an isolated electromagnetic cluster or one or more hard jets (UA1) or an isolated electron and one or two hard jets (UA2). Due to the enhanced data sample, the discovery of the intermediate vector bosons W and Z in 1983 was undoubtedly confirmed, and the nice agreement of their properties with the predictions of the electroweak theory was shown. In addition, many new results on experimental and theoretical jet physics were presented. The Tevatron Collider project and its planned experiments at Fermilab were discussed, and there were contributions about the possible future developments in theory (compositeness, supersymmetry) as well as in experimental high energy physics (Supercollider, Juratron). See hints under the relevant topics. (orig./HSI)

  15. Whole-body CT. Spiral and multislice CT. 2. tot. rev. and enl. ed.

    International Nuclear Information System (INIS)

    Prokop, M.; Galanski, M.; Schaefer-Prokop, C.; Molen, A.J. van der

    2007-01-01

    Spiral and multidetector techniques have improved the diagnostic possibilities of CT, so that image analysis and interpretation have become increasingly complex. This book represents the current state of the art in CT imaging, including the most recent technical scanner developments. The second edition comprises the current state of knowledge in cT imaging. There are new chapters on image processing, application of contrasting agents and radiation dose. All organ-specific pathological findings are discussed in full. There are hints for optimum use and interpretation of CT, including CT angiography, CT colonography, CT-IVPL, and 3D imaging. There is an introduction to cardio-CT, from calcium scoring and CTA of the coronary arteries to judgement of cardiac morphology. There are detailed scan protocols with descriptions of how to go about parameter selection. Practical hints are given for better image quality and lower radiation exposure of patients, guidelines for patient preparation and complication management, and more than 1900 images in optimum RRR quality. (orig.)

  16. Whole-body CT. Spiral and multislice CT. 2. tot. rev. and enl. ed.; Ganzkoerper-Computertomographie. Spiral- und Multislice-CT

    Energy Technology Data Exchange (ETDEWEB)

    Prokop, M.; Galanski, M.; Schaefer-Prokop, C.; Molen, A.J. van der

    2007-07-01

    Spiral and multidetector techniques have improved the diagnostic possibilities of CT, so that image analysis and interpretation have become increasingly complex. This book represents the current state of the art in CT imaging, including the most recent technical scanner developments. The second edition comprises the current state of knowledge in cT imaging. There are new chapters on image processing, application of contrasting agents and radiation dose. All organ-specific pathological findings are discussed in full. There are hints for optimum use and interpretation of CT, including CT angiography, CT colonography, CT-IVPL, and 3D imaging. There is an introduction to cardio-CT, from calcium scoring and CTA of the coronary arteries to judgement of cardiac morphology. There are detailed scan protocols with descriptions of how to go about parameter selection. Practical hints are given for better image quality and lower radiation exposure of patients, guidelines for patient preparation and complication management, and more than 1900 images in optimum RRR quality. (orig.)

  17. Rotationally resolved spectroscopy of Jupiter Trojans (624) Hektor and (911) Agamemnon

    Science.gov (United States)

    Perna, D.; Bott, N.; Hromakina, T.; Mazzotta Epifani, E.; Dotto, E.; Doressoundiram, A.

    2018-03-01

    We present the first-ever rotationally resolved spectroscopic investigation of (624) Hektor and (911) Agamemnon, the two largest Jupiter Trojans. The visible and near-infrared spectra that we have obtained at the TNG telescope (La Palma, Spain) do not show any feature or hints of heterogeneity. In particular, we found no hints of water-related absorptions. No cometary activity was detected down to ˜23.5 R mag arcsec-2 based on the complementary photometric data. We estimated upper limits on the dust production rates of Hektor and Agamemnon to be ≈30 and ≈24 kg s-1, respectively. We modelled complete visible and near-infrared spectra of our targets using the Shkuratov formalism to define the upper limit to the presence of water ice and more in general to constrain their surface composition. For both objects, successful models include amorphous carbon, magnesium-rich pyroxene, and kerogen, with an upper limit to the amount of water ice of a few per cent.

  18. Beyond the Investment Narrative

    Science.gov (United States)

    Moss, Peter

    2013-01-01

    The current policy interest in early childhood education and care is driven by an investment narrative, a story of quality and high returns emerging from a dominant neoliberal political economy. This short note expresses deep reservations about this narrative, and hints at another narrative that foregrounds democracy, experimentation and…

  19. Anneteparaad III / Karin Paulus

    Index Scriptorium Estoniae

    Paulus, Karin, 1975-

    2008-01-01

    Tutvustatakse Tartu Kõrgema Kunstikooli diplomandide lõputöid: 1. Diana Hints "Ba-Rokk", 2. Maire Rebina "Alleshoitud naeratused", 3. Liis Pihlik "Unistused ehk hingele pai", 4. Ille Agu "Pitsiring - pruudipesu kollektsioon", 5. Ingwald Koser "Chaise Longue", 6. Kaisa Paluoja installatsioon "/....../", 7. Kaidi Ploomipuu arvutiga juhitavatel telgedel kootud sisustuskangas

  20. Intentionality, consciousness, and creating community.

    Science.gov (United States)

    Malinski, Violet M

    2009-01-01

    Intentionality is briefly explored from the perspective of seminal written works on therapeutic touch and recorded conversations with Martha E. Rogers. This overview hints at possible interrelationships among intentionality, consciousness, and creating community, along with conceptual ambiguities, which are explored in detail by Zahourek and Larkin in this column.

  1. Elementary functional analysis

    CERN Document Server

    Shilov, Georgi E

    1996-01-01

    Introductory text covers basic structures of mathematical analysis (linear spaces, metric spaces, normed linear spaces, etc.), differential equations, orthogonal expansions, Fourier transforms - including problems in the complex domain, especially involving the Laplace transform - and more. Each chapter includes a set of problems, with hints and answers. Bibliography. 1974 edition.

  2. Evolution of direct mechanisms with incident energy from the Coulomb-barrier to relativistic energies. - Two-center effects in nucleon transfer between nuclei. - Signatures of nucleon promotion in heavy ion reactions at barrier energies

    International Nuclear Information System (INIS)

    Oertzen, W. von; Voit, H.; Imanishi, B.

    1988-10-01

    This report contains a review article considering the evolution of direct mechanisms with incident energy in heavy ion reactions and two theoretical articles concerning two-center effects in transfer reactions between heavy ions and the nucleon promotion in heavy ion reactions. See hints under the relevant topics. (HSI)

  3. Moving the Borders: Multiculturalism and Global Citizenship in the German Social Studies Classroom

    Science.gov (United States)

    Ortloff, Debora Hinderliter

    2011-01-01

    Background: In many countries, working towards a truly inclusive national citizenship means deconstructing hegemonic structures that are deeply entrenched. Moving outside of the borders toward a global citizenship hints at giving up on what has been a long road toward multicultural citizenship. A balance between including and empowering diverse…

  4. Linear algebra

    CERN Document Server

    Shilov, Georgi E

    1977-01-01

    Covers determinants, linear spaces, systems of linear equations, linear functions of a vector argument, coordinate transformations, the canonical form of the matrix of a linear operator, bilinear and quadratic forms, Euclidean spaces, unitary spaces, quadratic forms in Euclidean and unitary spaces, finite-dimensional space. Problems with hints and answers.

  5. Marxism and Communication.

    Science.gov (United States)

    Daley, Patrick J.; Soloski, John

    Karl Marx and Friedrich Engels had little to say specifically about communication and language, but their works hint at the direction their critique of communication might have taken. Language and consciousness are conditioned by specific means of production and sociopolitical circumstances and are therefore ideological. The domain of ideology…

  6. Creating an Opera with Seventh Graders.

    Science.gov (United States)

    Hower, Eileen

    1999-01-01

    Discusses the collaboration between an art and a music teacher whose seventh grade students wrote an opera based on the children's story "The Egyptian Cinderella." Addresses familiarizing students with composing music, student roles, and writing the compositions. Provides helpful hints and considers the benefits of this project. (CMK)

  7. Model Checking Real-Time Systems

    DEFF Research Database (Denmark)

    Bouyer, Patricia; Fahrenberg, Uli; Larsen, Kim Guldstrand

    2018-01-01

    This chapter surveys timed automata as a formalism for model checking real-time systems. We begin with introducing the model, as an extension of finite-state automata with real-valued variables for measuring time. We then present the main model-checking results in this framework, and give a hint...

  8. An Expert System-based Context-Aware Ubiquitous Learning Approach for Conducting Science Learning Activities

    Science.gov (United States)

    Wu, Po-Han; Hwang, Gwo-Jen; Tsai, Wen-Hung

    2013-01-01

    Context-aware ubiquitous learning has been recognized as being a promising approach that enables students to interact with real-world learning targets with supports from the digital world. Several researchers have indicated the importance of providing learning guidance or hints to individual students during the context-aware ubiquitous learning…

  9. Deaf child sexual education and family leadership

    Directory of Open Access Journals (Sweden)

    García, Mirna Maura

    2010-07-01

    Full Text Available This paper is an approach to the study of the role of the family in sexual education of deaf children and adolescents. The difference between hearing and deaf families is taken into consideration. Likewise, hints that favor communication between deaf children and hearing parents are given.

  10. Mastering Apple Aperture

    CERN Document Server

    Fitzgerald, Thomas

    2013-01-01

    Written in a conversational style, the author will share his knowledge on advanced Aperture topics with detailed discussions of advanced topics, the theory behind some of those topics and lots of hints and tips for ways to improve your workflow.Photographer's who have a basic understanding of Aperture

  11. Toward structural assessment of semi-arid African savannahs and woodlands: The potential of multitemporal polarimetric RADARSAT-2 fine beam images

    CSIR Research Space (South Africa)

    Mathieu, R

    2013-11-01

    Full Text Available variables but for all three seasons. The C-band SAR data thus provided encouraging results in open, semi-arid savannahs and hint at larger area structural assessments than is possible with LiDAR sensors alone. The combined use of C-band and L-band (ALOS...

  12. Annual report of scientific activities 1983 of the HMI, Bereich Kern- und Strahlenphysik

    International Nuclear Information System (INIS)

    1983-01-01

    This annual report contains the extended abstracts of the work performed at the named institute together with a list of publications and speeches. The work concerns theoretical nuclear physics, nuclear reactions, hyperfine interactions, atomic collisions, and developments of the VICKSI accelerator. See hints under the relevant topics. (HSI) [de

  13. College geometry a unified development

    CERN Document Server

    Kay, David C

    2011-01-01

    ""The book is a comprehensive textbook on basic geometry. … Key features of the book include numerous figures and many problems, more than half of which come with hints or even complete solutions. Frequent historical comments add to making the reading a pleasant one.""-Michael Joswig, Zentralblatt MATH 1273

  14. Ultra high energy cosmic rays above 10 GeV: Hints to new physics ...

    Indian Academy of Sciences (India)

    Ultra high energy cosmic rays; physics beyond standard model. ... The origin of the observed cosmic ray (CR) events above 10ѕј eV — the so-called ex- .... to arise simply from decay of some supermassive particles (of mass> 10ѕЅ eV) ...

  15. Is the CMS e e j j excess a hint for light supersymmetry?

    Science.gov (United States)

    Krauss, Manuel E.; Porod, Werner

    2015-09-01

    We discuss the impact of additional two-body decays of the right-handed neutrino into a light charged Higgs state on the dilepton plus dijet cross sections from resonant W' production. We consider in particular a supersymmetric left-right symmetric model which predicts such a light charged Higgs boson. We demonstrate that the e e j j excess as measured by CMS can be explained best if the W' also has decay modes into Higgsino-like charginos and neutralinos with masses of a few hundred GeV. Provided that this excess is confirmed, the model predicts also one right-handed neutrino with a mass below 200 GeV as well as a doubly charged Higgs boson which should be discovered at the LHC in the near future.

  16. Melatonin, Noncoding RNAs, Messenger RNA Stability and Epigenetics—Evidence, Hints, Gaps and Perspectives

    Science.gov (United States)

    Hardeland, Rüdiger

    2014-01-01

    Melatonin is a highly pleiotropic regulator molecule, which influences numerous functions in almost every organ and, thus, up- or down-regulates many genes, frequently in a circadian manner. Our understanding of the mechanisms controlling gene expression is actually now expanding to a previously unforeseen extent. In addition to classic actions of transcription factors, gene expression is induced, suppressed or modulated by a number of RNAs and proteins, such as miRNAs, lncRNAs, piRNAs, antisense transcripts, deadenylases, DNA methyltransferases, histone methylation complexes, histone demethylases, histone acetyltransferases and histone deacetylases. Direct or indirect evidence for involvement of melatonin in this network of players has originated in different fields, including studies on central and peripheral circadian oscillators, shift work, cancer, inflammation, oxidative stress, aging, energy expenditure/obesity, diabetes type 2, neuropsychiatric disorders, and neurogenesis. Some of the novel modulators have also been shown to participate in the control of melatonin biosynthesis and melatonin receptor expression. Future work will need to augment the body of evidence on direct epigenetic actions of melatonin and to systematically investigate its role within the network of oscillating epigenetic factors. Moreover, it will be necessary to discriminate between effects observed under conditions of well-operating and deregulated circadian clocks, and to explore the possibilities of correcting epigenetic malprogramming by melatonin. PMID:25310649

  17. Temporomandibular joint disorder complaints in tinnitus: further hints for a putative tinnitus subtype.

    Directory of Open Access Journals (Sweden)

    Veronika Vielsmeier

    Full Text Available OBJECTIVE: Tinnitus is considered to be highly heterogeneous with respect to its etiology, its comorbidities and the response to specific interventions. Subtyping is recommended, but it remains to be determined which criteria are useful, since it has not yet been clearly demonstrated whether and to which extent etiologic factors, comorbid states and interventional response are related to each other and are thus applicable for subtyping tinnitus. Analyzing the Tinnitus Research Initiative Database we differentiated patients according to presence or absence of comorbid temporomandibular joint (TMJ disorder complaints and compared the two groups with respect to etiologic factors. METHODS: 1204 Tinnitus patients from the Tinnitus Research Initiative (TRI Database with and without subjective TMJ complaints were compared with respect to demographic, tinnitus and audiological characteristics, questionnaires, and numeric ratings. Data were analysed according to a predefined statistical analysis plan. RESULTS: Tinnitus patients with TMJ complaints (22% of the whole group were significantly younger, had a lower age at tinnitus onset, and were more frequently female. They could modulate or mask their tinnitus more frequently by somatic maneuvers and by music or sound stimulation. Groups did not significantly differ for tinnitus duration, type of onset (gradual/abrupt, onset related events (whiplash etc., character (pulsatile or not, hyperacusis, hearing impairment, tinnitus distress, depression, quality of life and subjective ratings (loudness etc.. CONCLUSION: Replicating previous work in tinnitus patients with TMJ complaints, classical risk factors for tinnitus like older age and male gender are less relevant in tinnitus patients with TMJ complaints. By demonstrating group differences for modulation of tinnitus by movements and sounds our data further support the notion that tinnitus with TMJ complaints represents a subgroup of tinnitus with clinical features that are highly relevant for specific therapeutic management.

  18. Thermoelectric Properties of TI – Doped SnSe: A Hint of Phononic Structure

    Czech Academy of Sciences Publication Activity Database

    Kucek, V.; Plecháček, T.; Janíček, P.; Ruleová, P.; Beneš, L.; Navrátil, Jiří; Drašar, Č.

    2016-01-01

    Roč. 45, č. 6 (2016), s. 2943-2949 ISSN 0361-5235 R&D Projects: GA ČR(CZ) GA16-07711S Institutional support: RVO:61389013 Keywords : semiconductors * chalcogenides * X-ray diffraction Subject RIV: CA - Inorganic Chemistry Impact factor: 1.579, year: 2016

  19. A 3.55 keV hint for decaying axion-like particle dark matter

    Energy Technology Data Exchange (ETDEWEB)

    Jaeckel, Joerg [Heidelberg Univ. (Germany). Inst. fuer Theoretische Physik; Redondo, Javier [Muenchen Univ. (Germany). Arnold Sommerfeld Center; Max-Planck-Institut fuer Physik, Muenchen (Germany); Ringwald, Andreas [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2014-02-15

    Recently, indications for an emission line at 3.55 keV have been found in the combined spectra of a large number of galaxy clusters and also in Andromeda. This line could not be identified with any known spectral line. It is tempting to speculate that it has its origin in the decay of a particle contributing all or part of the dark matter. In this note we want to point out that axion-like particles being all or part of the dark matter are an ideal candidate to produce such a feature. More importantly the parameter values necessary are quite feasible in extensions of the Standard Model based on string theory and could be linked up to a variety of other intriguing phenomena, which also potentially allow for new tests of this speculation.

  20. Melatonin, Noncoding RNAs, Messenger RNA Stability and Epigenetics—Evidence, Hints, Gaps and Perspectives

    Directory of Open Access Journals (Sweden)

    Rüdiger Hardeland

    2014-10-01

    Full Text Available Melatonin is a highly pleiotropic regulator molecule, which influences numerous functions in almost every organ and, thus, up- or down-regulates many genes, frequently in a circadian manner. Our understanding of the mechanisms controlling gene expression is actually now expanding to a previously unforeseen extent. In addition to classic actions of transcription factors, gene expression is induced, suppressed or modulated by a number of RNAs and proteins, such as miRNAs, lncRNAs, piRNAs, antisense transcripts, deadenylases, DNA methyltransferases, histone methylation complexes, histone demethylases, histone acetyltransferases and histone deacetylases. Direct or indirect evidence for involvement of melatonin in this network of players has originated in different fields, including studies on central and peripheral circadian oscillators, shift work, cancer, inflammation, oxidative stress, aging, energy expenditure/obesity, diabetes type 2, neuropsychiatric disorders, and neurogenesis. Some of the novel modulators have also been shown to participate in the control of melatonin biosynthesis and melatonin receptor expression. Future work will need to augment the body of evidence on direct epigenetic actions of melatonin and to systematically investigate its role within the network of oscillating epigenetic factors. Moreover, it will be necessary to discriminate between effects observed under conditions of well-operating and deregulated circadian clocks, and to explore the possibilities of correcting epigenetic malprogramming by melatonin.

  1. A 3.55 keV hint for decaying axion-like particle dark matter

    International Nuclear Information System (INIS)

    Jaeckel, Joerg; Ringwald, Andreas

    2014-02-01

    Recently, indications for an emission line at 3.55 keV have been found in the combined spectra of a large number of galaxy clusters and also in Andromeda. This line could not be identified with any known spectral line. It is tempting to speculate that it has its origin in the decay of a particle contributing all or part of the dark matter. In this note we want to point out that axion-like particles being all or part of the dark matter are an ideal candidate to produce such a feature. More importantly the parameter values necessary are quite feasible in extensions of the Standard Model based on string theory and could be linked up to a variety of other intriguing phenomena, which also potentially allow for new tests of this speculation.

  2. Is the Earth's magnetic field heading for a flip? Hints from the past

    Science.gov (United States)

    Laj, C. E.; Kissel, C.

    2017-12-01

    The magnitude of the Earth's dipole magnetic field has decreased significantly over the last centuries at a mean rate of 16 nT/y. This decrease, which correlates with the growth of the South Atlantic Anomaly (SAA) therefore occurs at a rate which is about 10 times larger than expected from a free Ohmic decay process. This situation has led to speculations that an attempt to a reversal or a geomagnetic excursion might be underway. We investigate this hypothesis by examining past geomagnetic instabilities, focussing on the well documented Laschamp and Mono Lake excursions. We have selected high accumulation sedimentary records with very precise age model, leading to unprecedented temporal resolution, and accurate calibration of RPI between 20 and 75 kyr B.P. We also used the 10Be and 36Cl records from the Greenland ice cores. The rate of decay of the field intensity during these two excursions is virtually identical to that observed over the last centuries and much higher than that observed for another period of low intensity (around 65 kyr BP) not associated with a polarity change. Moreover, the global morphology of the Laschamp excursion obtained by Bayesian inversion (Leonhardt et al. (2009) is that reverse magnetic field patches at the core-mantle boundary are formed near the equator and then move poleward, a scenario reminiscent of that described for the present field in the litterature. Therefore, although these results from two excursions do not provide undisputable information on future evolution of the field, they show similarities with several aspects of the present-day geomagnetic field. Assuming that the dynamo processes for an eventual future instability would be similar to those of the past two excursions, we tentatively suggest that, whilst irreversible processes that will drive the geodynamo into a polarity change may have already started, some 1000 years would be needed for the directional changes to start to be significant.

  3. Robustness of circadian clocks to daylight fluctuations: hints from the picoeucaryote Ostreococcus tauri.

    Directory of Open Access Journals (Sweden)

    Quentin Thommen

    Full Text Available The development of systemic approaches in biology has put emphasis on identifying genetic modules whose behavior can be modeled accurately so as to gain insight into their structure and function. However, most gene circuits in a cell are under control of external signals and thus, quantitative agreement between experimental data and a mathematical model is difficult. Circadian biology has been one notable exception: quantitative models of the internal clock that orchestrates biological processes over the 24-hour diurnal cycle have been constructed for a few organisms, from cyanobacteria to plants and mammals. In most cases, a complex architecture with interlocked feedback loops has been evidenced. Here we present the first modeling results for the circadian clock of the green unicellular alga Ostreococcus tauri. Two plant-like clock genes have been shown to play a central role in the Ostreococcus clock. We find that their expression time profiles can be accurately reproduced by a minimal model of a two-gene transcriptional feedback loop. Remarkably, best adjustment of data recorded under light/dark alternation is obtained when assuming that the oscillator is not coupled to the diurnal cycle. This suggests that coupling to light is confined to specific time intervals and has no dynamical effect when the oscillator is entrained by the diurnal cycle. This intriguing property may reflect a strategy to minimize the impact of fluctuations in daylight intensity on the core circadian oscillator, a type of perturbation that has been rarely considered when assessing the robustness of circadian clocks.

  4. Avalikustamiskohustuse rikkumine Eesti väärtpaberituruõiguses : tsiviilõiguslikud kaitsevahendid / Meelis Hint

    Index Scriptorium Estoniae

    Hint, Meelis, 1981-

    2003-01-01

    Väärtpaberite avalikustamiskohustusest, tehingu tühistamisest, kahju hüvitamisest, väärtpaberite müügist, kahju hüvitamisest rikkumiste korral ja tehingu tühistamisest väärtpaberite järelturul

  5. Hints on the high-energy seesaw mechanism from the low-energy neutrino spectrum

    International Nuclear Information System (INIS)

    Casas, J.A.; Jimenez-Alburquerque, F.

    2006-12-01

    It is an experimental fact that the mass ratio for the two heavier neutrinos, h=m 3 /m 2 3 /m 2 >> m 3 /m 2 , so m 1 should be extremely tiny. Also, the V R matrix associated to the neutrino Yukawa couplings has a far from random structure, naturally resembling V CKM . In fact we show that identifying V R and V CKM , as well as neutrino and u-quark Yukawa couplings can reproduce h exp in a highly non-trivial way, which is very suggestive. The physical implications of these results are also discussed. (orig.)

  6. Using the ERT method in tectonically active areas: hints from Southern Apennine (Italy

    Directory of Open Access Journals (Sweden)

    A. Giocoli

    2008-11-01

    Full Text Available Electrical Resistivity Tomography (ERT method has been used to study two tectonically active areas of southern Apennine (Caggiano Faults and Ufita Basin. The main aim of this job was to study the structural setting of the investigated areas, i.e. the geometry of the basins at depth, the location of active faults at surface, and their geometrical characterization. The comparison between ERT and trench/drilling data allowed us to evaluate the efficacy of the ERT method in studying active faults and the structural setting of seismogenic areas.

    In the Timpa del Vento intermontane basin, high resolution ERT across the Caggiano Fault scarps, with different arrays, electrode spacing (from 1 to 10 m and penetration depth (from about 5 to 40 m was carried out. The obtained resistivity models allowed us to locate the fault planes along the hillslope and to gather information at depth, as later confirmed by paleoseismological trenches excavated across the fault trace.

    In the Ufita River Valley a 3560-m-long ERT was carried out across the basin, joining 11 roll-along multi-channel acquisition system with an electrode spacing of 20 m and reaching an investigation depth of about 170 m. The ERT allowed us to reconstruct the geometry and thickness of the Quaternary deposits filling the Ufita Valley. Our reconstruction of the depositional setting is in agreement with an interpretative geological section based on borehole data.

  7. Virtual environment to quantify the influence of colour stimuli on the performance of tasks requiring attention

    Directory of Open Access Journals (Sweden)

    Frère Annie F

    2011-08-01

    Full Text Available Abstract Background Recent studies indicate that the blue-yellow colour discrimination is impaired in ADHD individuals. However, the relationship between colour and performance has not been investigated. This paper describes the development and the testing of a virtual environment that is capable to quantify the influence of red-green versus blue-yellow colour stimuli on the performance of people in a fun and interactive way, being appropriate for the target audience. Methods An interactive computer game based on virtual reality was developed to evaluate the performance of the players. The game's storyline was based on the story of an old pirate who runs across islands and dangerous seas in search of a lost treasure. Within the game, the player must find and interpret the hints scattered in different scenarios. Two versions of this game were implemented. In the first, hints and information boards were painted using red and green colours. In the second version, these objects were painted using blue and yellow colours. For modelling, texturing, and animating virtual characters and objects the three-dimensional computer graphics tool Blender 3D was used. The textures were created with the GIMP editor to provide visual effects increasing the realism and immersion of the players. The games were tested on 20 non-ADHD volunteers who were divided into two subgroups (A1 and A2 and 20 volunteers with ADHD who were divided into subgroups B1 and B2. Subgroups A1 and B1 used the first version of the game with the hints painted in green-red colors, and subgroups A2 and B2 the second version using the same hints now painted in blue-yellow. The time spent to complete each task of the game was measured. Results Data analyzed with ANOVA two-way and posthoc TUKEY LSD showed that the use of blue/yellow instead of green/red colors decreased the game performance of all participants. However, a greater decrease in performance could be observed with ADHD participants

  8. Possibilities of mathematical models in solving flow problems in environmental protection and water architecture

    Energy Technology Data Exchange (ETDEWEB)

    1979-01-01

    The booklet presents the full text of 13 contributions to a Colloquium held at Karlsruhe in Sept. 1979. The main topics of the papers are the evaluation of mathematical models to solve flow problems in tide water, seas, rivers, groundwater and in the earth atmosphere. See further hints under relevant topics.

  9. A climatological study of the relations among solar activity, galactic ...

    Indian Academy of Sciences (India)

    Though correlation study between precipitation and other parameters do not hint any linear relation, still the Fourier and wavelet analyses give an idea of common periodicities. The 9–11 year periodicity of sunspot numbers calculated by Fourier transform is also confirmed by wavelet transform in annual scale. Similarly ...

  10. No nuclear safety without security

    International Nuclear Information System (INIS)

    Anon.

    2016-01-01

    ead of Health and Safety - Nuclear Safety and Corporate Security at ENGIE Benelux, Pierre Doumont has the delicate job of defining and implementing measures, including cybersecurity, to prevent the risk of malevolent acts against tangible and intangible assets. He gives some hints on the contribution of nuclear security to safety.

  11. Feeding Your 4- to 7-Month-Old

    Science.gov (United States)

    ... check with your doctor before giving any solid foods. Is My Baby Ready to Eat Solids? How can you tell if your baby is ready for solids? Here are a few hints: Is your baby's tongue-thrust ... causes them to push food out of their mouths. Can your baby support ...

  12. Model solutions and properties for diagnosing student programs in Ask-Elle

    NARCIS (Netherlands)

    Jeuring, Johan; Binsbergen, Thomas~van; Gerdes, Alex; Heeren, Bastiaan

    2014-01-01

    Ask-Elle is an interactive tutor that supports the stepwise development of simple functional programs. Using Ask-Elle students receive feedback about whether or not they are on the right track, they can ask for a hint when they are stuck, and get suggestions about how to refactor their program. Our

  13. Constraints on the neutrino emission from the Galactic Ridge with the ANTARES telescope

    NARCIS (Netherlands)

    Adrián-Martínez, S.; Albert, A.; André, M.; Anghinolfi, M.; Anton, G.; Ardid, M.; Aubert, J.-J.; Avgitas, T.; Baret, B.; Barrios-Martí, J.; Basa, S.; Bertin, V.; Biagi, S.; Bormuth, R.; Bouwhuis, M.C.; Bruijn, R.; Brunner, J.; Busto, J.; Capone, A.; Caramete, L.; Carr, J.; Celli, S.; Chiarusi, T.; Circella, M.; Coleiro, A.; Coniglione, R.; Costantini, H.; Coyle, P.; Creusot, A.; Deschamps, A.; De Bonis, G.; Distefano, C.; Donzaud, C.; Dornic, D.; Drouhin, D.; Eberl, T.; El Bojaddaini, I.; Elsässer, D.; Enzenhöfer, A.; Fehn, K.; Felis, I.; Fusco, L.A.; Galatà, S.; Gay, P.; Geißelsöder, S.; Geyer, K.; Giordano, V.; Gleixner, A.; Glotin, H.; Gracia-Ruiz, R.; Graf, K.; Hallmann, S.; van Haren, H.; Heijboer, A.J.; Hello, Y.; Hernández-Rey, J.J.; Hößl, J.; Hofestädt, J.; Hugon, C.; Illuminati, C.; James, C.W.; de Jong, M.; Kadler, M.; Kalekin, O.; Katz, U.; Kießling, D.; Kouchner, A.; Kreter, M.; Kreykenbohm, I.; Kulikovskiy, V.; Lachaud, C.; Lahmann, R.; Lefèvre, D.; Leonora, E.; Loucatos, S.; Marcelin, M.; Margiotta, A.; Marinelli, A.; Martínez-Mora, J.A.; Mathieu, A.; Michael, T.; Migliozzi, P.; Moussa, A.; Mueller, C.; Nezri, E.; Păvălaş, G.E.; Pellegrino, C.; Perrina, C.; Piattelli, P.; Popa, V.; Pradier, T.; Racca, C.; Riccobene, G.; Roensch, K.; Saldaña, M.; Samtleben, D.F.E.; Sánchez-Losa, A.; Sanguineti, M.; Sapienza, P.; Schnabel, J.; Schüssler, F.; Seitz, T.; Sieger, C.; Spurio, M.; Stolarczyk, T.; Taiuti, M.; Trovato, A.; Tselengidou, M.; Turpin, D.; Tönnis, C.; Vallage, B.; Vallée, C.; Van Elewyck, V.; Visser, E.; Vivolo, D.; Wagner, S.; Wilms, J.; Zornoza, J.D.; Zúñiga, J.

    A highly significant excess of high-energy astrophysical neutrinos has been reported by the IceCube Collaboration. Some features of the energy and declination distributions of IceCube events hint at a North/South asymmetry of the neutrino flux. This could be due to the presence of the bulk of our

  14. The Right Time to Start Writing

    Science.gov (United States)

    Casa, Tutita M.

    2015-01-01

    Communication has long been emphasized in standards-based instruction (NCTM 1991; 2000), yet little distinction has been made between oral and written forms. Nonetheless, both the mathematics and the English language arts Common Core State Standards (CCSS) documents continue to hint at the importance of writing mathematically (CCSSI 2010). The…

  15. Download this PDF file

    African Journals Online (AJOL)

    Information Technology

    continuation of traditional practices in the design of new general-purpose dic- tionaries which were published within this period, the increasingly central role of the computer in dictionary work, and the negative effects computerization is having on lexicography as "industry". Why the change in title? The author hints at an ...

  16. Understanding reading problems in secondary schools: Some ...

    African Journals Online (AJOL)

    ... factors are discussed based on the evidence obtained by observations and research findings. The importance of teaching reading 'as a subject in the secondary school is hinted. Recommendations are made to ensure that reading as a tool to learning is given a prominent place in schools and libraries throughout Nigeria ...

  17. Aerosols in science medicine and technology

    International Nuclear Information System (INIS)

    Stoeber, W.; Hochrainer, D.

    1981-01-01

    This volume contains all papers presented at the 9th conference of the Association for Aerosol Research held in Duisburg, Germany F.R. in September 1981. This conference was attented by 160 participants and there were 39 oral and 16 poster presentations. For detailed hints see under relevant topics. (RW)

  18. Effective field theory approach to $b\\to s\\ell\\ell^{(\\prime)}$, $B\\to K^{(*)}\

    CERN Document Server

    Calibbi, Lorenzo; Ota, Toshihiko

    2015-01-01

    LHCb reported anomalies in $B\\to K^* \\mu^+\\mu^-$, $B_s\\to\\phi\\mu^+\\mu^-$ and $R(K)=B\\to K \\mu^+\\mu^-/B\\to K e^+e^-$. Furthermore, BaBar, BELLE and LHCb found hints for the violation of lepton flavour universality violation in $R(D^{(*)})=B\\to D^{(*)}\\tau\

  19. A Teaching Method on Basic Chemistry for Freshman (II) : Teaching Method with Pre-test and Post-test

    OpenAIRE

    立木, 次郎; 武井, 庚二

    2004-01-01

    This report deals with review of a teaching method on basic chemistry for freshman in this first semester. We tried to review this teaching method with pre-test and post-test by means of the official and private questionnaires. Several hints and thoughts on teaching skills are obtained from this analysis.

  20. Wireless communications surpassing fiber capacity : micro- and millimeter-wave solutions up to D-band for 5G systems

    NARCIS (Netherlands)

    Olmos, J. J.Vegas; Monroy, I. Tafur

    2017-01-01

    In this paper, we present the latest experimental work on millimetre-wave links operating at fiber-like capacity regimes: from UWB communications supporting up to 35 Gbit/s to D-band communications operating at 352 Gbit/s. We provide insights on these technologies and hints on next steps to achieve

  1. Effects of yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 on the IgA flow rate of saliva in elderly persons residing in a nursing home: A before-after non-randomised intervention study.

    Science.gov (United States)

    Yamamoto, Yuko; Fujino, Kazuhiro; Saruta, Juri; Takahashi, Toru; To, Masahiro; Fuchida, Shinya; Shimizu, Tomoko; Kamata, Yohei; Misawa, Kyoko; Tsukinoki, Keiichi

    2017-12-01

    The aim of this study was to investigate the alterations in the salivary IgA levels of elderly persons administered yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus (L. bulgaricus) OLL1073R-1, which has been reported to reduce the risk of colds. Salivary immunoglobulin (Ig)A plays an important role in the defence of the oral cavity mucous membrane against foreign antigens and pathogens. Accordingly, low levels of salivary IgA are associated with an increased risk of upper respiratory tract infection. Furthermore, salivary IgA secretion has been reported to decrease with age. Recently, several studies have reported that certain strains of Lactobacillus and their products can modulate the immune response, but there are currently few studies on the effects of on the IgA level in human saliva. This was a before-after non-randomised intervention study. Thirty-seven elderly persons (mean age, 82.7 years) residing in a single nursing home ingested 112 g of the yogurt every morning for 12 weeks. The participants' saliva was collected before and after 4, 8 and 12 weeks of yogurt intake. Our results showed that yogurt intake affected the concentration of IgA in the saliva (P < .0001). Additionally, yogurt intake and the body weight of the participants affected the IgA flow rate of saliva (P = .0003 and .03, respectively). Continuous intake of yogurt fermented with L. bulgaricus OLL1073R-1 may help improve the mucosal immune function in elderly people with weakened immune systems. © 2017 John Wiley & Sons A/S and The Gerodontology Association. Published by John Wiley & Sons Ltd.

  2. Battle of the quarks

    CERN Multimedia

    Cho, A

    2001-01-01

    The search for QGP has sparked a war of words between rival physicists in the US and Europe. Researchers from Brookhaven reported that RHIC had show intriguing hints that it could be making the plasma. Researchers at CERN though stand by their claim that the SPS already makes the stuff (1 page).

  3. Lilleilu rehe all / Elvi Nassar

    Index Scriptorium Estoniae

    Nassar, Elvi

    2009-01-01

    Näitus "Lillemotiiv moevormil" Eesti Vabaõhumuuseumis Pulga talu rehe all. Näitusel oli väljas paarkümmend fliseliini ja paberisse liimitud-vormitud-kägardatud kleiti. Muuseumi töötoas tutvustas pakutrüki- ja origamitehnikat jaapani disainer Yumiko Okazaki. Osalesid Anu Hint, Anne Metsis, Monika Kisand, Juta Piirlaid

  4. Coping Styles with Student Misbehavior as Mediators of Teachers' Classroom Management Strategies

    Science.gov (United States)

    Tran, Van Dat

    2016-01-01

    The purpose of the present study is to identify how teachers' use of various coping styles with student misbehavior, and the extent to which these relate to their classroom management techniques -- punishment, recognition and reward, hinting, discussion, and aggression. It examines data from 397 junior high school teachers in Vietnam. The results…

  5. An Analysis of Young Students' Thinking When Completing Basic Coding Tasks Using Scratch Jnr. on the iPad

    Science.gov (United States)

    Falloon, G.

    2016-01-01

    Recent government moves in many countries have seen coding included in school curricula, or promoted as part of computing, mathematics or science programmes. While these moves have generally been associated with a need to engage more young people in technology study, research has hinted at possible benefits from learning to program including…

  6. Letters of Stone. From Nazi Germany to South Africa. Steven Robins ...

    African Journals Online (AJOL)

    merely hint at the gruesome reality in Nazi Germany. With the hindsight granted to present-day readers, we know the fate that awaited these men and women as an elongated and agonising social death reached its culmination in systematic mass murder. In describing his journeys to Germany,. Poland, Israel and the United ...

  7. Ask-Elle: An Adaptable Programming Tutor for Haskell Giving Automated Feedback

    Science.gov (United States)

    Gerdes, Alex; Heeren, Bastiaan; Jeuring, Johan; van Binsbergen, L. Thomas

    2017-01-01

    Ask-Elle is a tutor for learning the higher-order, strongly-typed functional programming language Haskell. It supports the stepwise development of Haskell programs by verifying the correctness of incomplete programs, and by providing hints. Programming exercises are added to Ask-Elle by providing a task description for the exercise, one or more…

  8. The 100 Best Targets for Astrophotography

    CERN Document Server

    Kier, Ruben

    2009-01-01

    Reveals, for each month of the year, the choicest celestial treasures within the reach of a commercial CCD camera. This book includes hints and advice on framing, exposures, and filters. It focuses on what northern latitude objects to image at any given time of the year to get the most spectacular results

  9. The behavioural response of the professional buyer on social cues from the vendor and how to measure it

    NARCIS (Netherlands)

    van Zeeland-van der Holst, Eveline Maria; Henseler, Jörg

    2018-01-01

    Purpose Vendors’ social cues ─ physical or behavioural hints ─ have an impact on the professional buyer. However, little is known about that impact. The purpose of this paper is to place knowledge about the impact of social cues that other disciplines acquired in the context of B2B marketing in

  10. In search of high density collective phenomena in nuclear collision

    International Nuclear Information System (INIS)

    Gyulassy, M.

    1979-06-01

    The progress made toward uncovering signatures of collective phenomena is reviewed. Elements of the basic reaction mechanism leading to a complex background are first discussed. Possible hints of collective phenomena in proton and pion single and double inclusive spectra as well as π - multiplicity data are then described. 6 figures, 2 tables

  11. Frontier detectors for frontier physics

    International Nuclear Information System (INIS)

    Cervelli, F.; Scribano, A.

    1984-01-01

    These proceedings contain the articles presented at the named meeting. These concern developments of radiation detectors and counting techniques in high energy physics. Especially considered are tracking detectors, calorimeters, time projection chambers, detectors for rare events, solid state detectors, particle identification, and optical readout systems. See hints under the relevant topics. (HSI)

  12. Environmental policy and environmental protection

    International Nuclear Information System (INIS)

    1980-01-01

    The political, economic, scientific and international dimensions of the subject are discussed with a view to teaching at school. To get a better picture, there is no division between the information section and the didactic part. The didactic part contains full-text examples and hints for their use in teaching. (HP) [de

  13. Terraforming The Creating of Habitable Worlds

    CERN Document Server

    Beech, Martin

    2009-01-01

    Often used as the narrative premise in science fiction novels, terraforming is the process by which an uninhabitable planet might be converted into one capable of supporting life. This book proposes an exploration on the topic of terraforming. It presents what is physically possible and hints what might conceivably be put into practice

  14. Neutrino μ - τ reflection symmetry and its breaking in the minimal seesaw

    OpenAIRE

    Liu, Zhi-Cheng; Yue, Chong-Xing; Zhao, Zhen-Hua

    2017-01-01

    In this paper, we attempt to implement the neutrino $\\mu$-$\\tau$ reflection symmetry (which predicts $\\theta^{}_{23} = \\pi/4$ and $\\delta = \\pm \\pi/2$ as well as trivial Majorana phases) in the minimal seesaw (which enables us to fix the neutrino masses). For some direct (the preliminary experimental hints towards $\\theta^{}_{23} \

  15. Are DACA Students Still Safe to Stay?

    Science.gov (United States)

    Patel, Pooja

    2017-01-01

    The Trump administration has sent mixed signals about the future of the DACA program, creating uncertainty among recipients and their families. A leaked draft of an internal memo hinted that the Trump administration intends to cut the Deferred Action for Childhood Arrivals (DACA) program. Given such ambiguity, advocates like Gregory Chen, the…

  16. Vector and parallel processors in computational science

    International Nuclear Information System (INIS)

    Duff, I.S.; Reid, J.K.

    1985-01-01

    These proceedings contain the articles presented at the named conference. These concern hardware and software for vector and parallel processors, numerical methods and algorithms for the computation on such processors, as well as applications of such methods to different fields of physics and related sciences. See hints under the relevant topics. (HSI)

  17. Science.gov: gateway to government science information.

    Science.gov (United States)

    Fitzpatrick, Roberta Bronson

    2010-01-01

    Science.gov is a portal to more than 40 scientific databases and 200 million pages of science information via a single query. It connects users to science information and research results from the U.S. government. This column will provide readers with an overview of the resource, as well as basic search hints.

  18. Pedagogy and Japanese Culture in a Distance Learning Environment

    Science.gov (United States)

    Anderson, Bodi O.

    2012-01-01

    Current theoretical models of distance learning are driven by two impetuses: a technical CMC element, and a pedagogical foundation rooted strongly in the Western world, and driven by social constructivism. By and large these models have been exported throughout the world as-is. However, previous research has hinted at potential problems with these…

  19. 11th ECR ion source workshop

    International Nuclear Information System (INIS)

    1993-05-01

    This report contains four articles concerning the commissioning of the 14 GHz ECR at the new Unilac injector, the status of the PuMa-ECR, the redesigned 14 GHz ECR ion source and test bench, and the simulation of ion beam extraction from an ECR source. See hints under the relevant topics. (HSI)

  20. Analogical Reasoning in Adolescents with Intellectual Disability: Effects of External Memories and Time Processing

    Science.gov (United States)

    Denaes, Caroline; Berger, Jean-Louis

    2014-01-01

    Analogical reasoning involves the comparison of pictures as well as the memorisation of relations. Young children (4-7 years old) and students with moderate intellectual disability have a short memory span, which hampers them in succeeding traditional analogical tests. In the present study, we investigated if, by providing external memory hints,…

  1. Understanding neutrino masses and mixings

    Indian Academy of Sciences (India)

    various possible oscillation solutions to the solar neutrino puzzle. It seems .... A first hint of this new ingredient came from the observation of Weinberg that if ..... Using the discussion of the above paragraph, the Dirac mass of the neutrino as .... that contributes to charged fermion masses, one can write the quark and lepton.

  2. (AJST) A CUTTING- PLANE APPROACH FOR SEMI- INFINITE ...

    African Journals Online (AJOL)

    opiyo

    Section 3 deals with convex semi-infinite programming while in section 4 we give some hints for dealing with the geometric case. The paper ends with concluding remarks along with a comparison of the cutting-plane philosophy with other existing approaches and a claim for implementing. Decision Support System for this ...

  3. Differentiation of Teaching Learning Process in the area of ​​Exact Sciences in IPUEC of the province of Pinar del Río

    Directory of Open Access Journals (Sweden)

    Carlos Manuel Caraballo Carmona

    2004-06-01

    Full Text Available This article presents some hints About the historical development of the differentiation of the Teaching Learning Process in the area of Exact Sciences knowledge in Pinar del Rio provincie IPUECs, and it Permits the observation of the evolution of the problem, ITS Successes and errors in the strategies Followed.

  4. e+e- collisions at 500 GeV: The physics potential. Pt. C. Proceedings

    International Nuclear Information System (INIS)

    Zerwas, P.M.

    1993-12-01

    These proceedings contain the articles presented at the named workshop. These concern the production of Higgs bosons, electroweak gauge bosons, top particles, particles required by grand unification, supersymmetric particles in 500 Gev e + e - interactions together with γγ physics and some description of collider detectors. See hints under the relevant topics. (HSI)

  5. X-Ray Astronomy--A New View of the Sky From Space

    Science.gov (United States)

    Gursky, Herbert

    1973-01-01

    Objects and energy sources are detected whose existence was only hinted at a few years ago. The X-Ray sky has a large number of sources along the Milky Way, most of which lie within 30 degrees of the galactic center, plus a number of faint sources associated with external galaxies. (DF)

  6. Eesti Disainiauhinnad 2012

    Index Scriptorium Estoniae

    2012-01-01

    Bruno 2012 parima tootedisaini kategoorias võitis Margus Triibmanni rattahoidja TULIP FAN FAN. Parim disainiprojekt - KOKO Arhitektide projekteeritud Lennusadam. Noore disaineri auhind Säsi läks jagamisele Kärt Ojavee, Elena Karelsoni ja Indrek Sirkeli vahel. Grand prix omistati trükisele "HULA. Inimeste peal testitud" (disainerid Mariana Hint, Agnes Ratas)

  7. The BOLD Response during Stroop Task-Like Inhibition Paradigms: Effects of Task Difficulty and Task-Relevant Modality

    Science.gov (United States)

    Mitchell, Rachel L. C.

    2005-01-01

    Previous studies of the Stroop task propose two key mediators: the prefrontal and cingulate cortices but hints exist of functional specialization within these regions. This study aimed to examine the effect of task modality upon the prefrontal and cingulate response by examining the response to colour, number, and shape Stroop tasks whilst BOLD…

  8. Exopolysaccharides from Lactobacillus delbrueckii OLL1073R-1 modulate innate antiviral immune response in porcine intestinal epithelial cells.

    Science.gov (United States)

    Kanmani, Paulraj; Albarracin, Leonardo; Kobayashi, Hisakazu; Iida, Hikaru; Komatsu, Ryoya; Humayun Kober, A K M; Ikeda-Ohtsubo, Wakako; Suda, Yoshihito; Aso, Hisashi; Makino, Seiya; Kano, Hiroshi; Saito, Tadao; Villena, Julio; Kitazawa, Haruki

    2018-01-01

    Previous studies demonstrated that the extracellular polysaccharides (EPSs) produced by Lactobacillus delbrueckii OLL1073R-1 (LDR-1) improve antiviral immunity, especially in the systemic and respiratory compartments. However, it was not studied before whether those EPSs are able to beneficially modulate intestinal antiviral immunity. In addition, LDR-1-host interaction has been evaluated mainly with immune cells while its interaction with intestinal epithelial cells (IECs) was not addressed before. In this work, we investigated the capacity of EPSs from LDR-1 to modulate the response of porcine IECs (PIE cells) to the stimulation with the Toll-like receptor (TLR)-3 agonist poly(I:C) and the role of TLR2, TLR4, and TLR negative regulators in the immunoregulatory effect. We showed that innate immune response triggered by TLR3 activation in porcine IECs was differentially modulated by EPS from LDR-1. EPSs treatment induced an increment in the expression of interferon (IFN)-α and IFN-β in PIE cells after the stimulation with poly(I:C) as well as the expression of the antiviral factors MxA and RNase L. Those effects were related to the reduced expression of A20 in EPS-treated PIE cells. EPS from LDR-1 was also able to reduce the expression of IL-6 and proinflammatory chemokines. Although further in vivo studies are needed, our results suggest that these EPSs or a yogurt fermented with LDR-1 have potential to improve intestinal innate antiviral response and protect against intestinal viruses. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. Soil organic carbon loss and selective transportation under field simulated rainfall events.

    Science.gov (United States)

    Nie, Xiaodong; Li, Zhongwu; Huang, Jinquan; Huang, Bin; Zhang, Yan; Ma, Wenming; Hu, Yanbiao; Zeng, Guangming

    2014-01-01

    The study on the lateral movement of soil organic carbon (SOC) during soil erosion can improve the understanding of global carbon budget. Simulated rainfall experiments on small field plots were conducted to investigate the SOC lateral movement under different rainfall intensities and tillage practices. Two rainfall intensities (High intensity (HI) and Low intensity (LI)) and two tillage practices (No tillage (NT) and Conventional tillage (CT)) were maintained on three plots (2 m width × 5 m length): HI-NT, LI-NT and LI-CT. The rainfall lasted 60 minutes after the runoff generated, the sediment yield and runoff volume were measured and sampled at 6-min intervals. SOC concentration of sediment and runoff as well as the sediment particle size distribution were measured. The results showed that most of the eroded organic carbon (OC) was lost in form of sediment-bound organic carbon in all events. The amount of lost SOC in LI-NT event was 12.76 times greater than that in LI-CT event, whereas this measure in HI-NT event was 3.25 times greater than that in LI-NT event. These results suggest that conventional tillage as well as lower rainfall intensity can reduce the amount of lost SOC during short-term soil erosion. Meanwhile, the eroded sediment in all events was enriched in OC, and higher enrichment ratio of OC (ERoc) in sediment was observed in LI events than that in HI event, whereas similar ERoc curves were found in LI-CT and LI-NT events. Furthermore, significant correlations between ERoc and different size sediment particles were only observed in HI-NT event. This indicates that the enrichment of OC is dependent on the erosion process, and the specific enrichment mechanisms with respect to different erosion processes should be studied in future.

  10. Moskvalased näevad eesti nüüdiskunsti / Johannes Saar

    Index Scriptorium Estoniae

    Saar, Johannes, 1965-

    2007-01-01

    Moskvas nüüdiskunsti keskuses avatakse 19.09.2007 eesti kunstnike grupinäitus "Tagurpidi bluus". Anna Hints, Laura Kuusk, Neeme Külm, Kristina Norman, Jüri Ojaver, Jaan Paavle, Jaan Toomik ja Paul Rodgers pakuvad videos, fotos ja installatsioonides mõtlemisainet kultuurilise konsensuse üle. Näituse korraldaja on Kaasaegse Kunsti Eesti Keskus

  11. Heisenberg and Ferromagnetism

    Indian Academy of Sciences (India)

    how Heisenberg identified the quantum mechan- ical exchange ... condensed matter physics from the Indian ... electrons per atom and 'm,' is the electronic mass. Dia- magnetism is .... what is the origin of this ordering field Hint = aM, that gives rise to a ... the case with magnetism, where the fundamental Inech- anism for the ...

  12. Learning to See History: A Content Analysis of the Affordances of Graphic Novels for High School Teaching

    Science.gov (United States)

    Boerman-Cornell, William

    2012-01-01

    Recent studies of graphic novels (book-length fiction or non-fiction narratives that employ the conventions of comic books to convey meaning) and multimodality have hinted that graphic novels (GNs) might offer a great deal of meaning-making potential to readers. Some studies have argued that graphic novels could be useful for English Language…

  13. Structure and distribution of cross-links in boron-modified phenol-formaldehyde resins designed for soft magnetic composites: a multiple-quantum 11B-11B MAS NMR correlation spectroscopy study

    Czech Academy of Sciences Publication Activity Database

    Kobera, Libor; Czernek, Jiří; Strečková, M.; Urbanová, Martina; Abbrent, Sabina; Brus, Jiří

    2015-01-01

    Roč. 48, č. 14 (2015), s. 4874-4881 ISSN 0024-9297 R&D Projects: GA MŠk(CZ) LD14010 Grant - others:European Commission(XE) COST Action MP1202 HINT Institutional support: RVO:61389013 Keywords : phenol-formaldehyde polymers * boron crosslinks * soft magnetic composites Subject RIV: CD - Macromolecular Chemistry Impact factor: 5.554, year: 2015

  14. Filmiankeet

    Index Scriptorium Estoniae

    1986-01-01

    Vastavad M. Balbat, Õ. Orav, L. Priimägi, T. Kallas, P. Simm, A. Valton, J. Ruus, S. Školnikov, K. Tamberg, I. Unt, P. Simm, T. Elmanovitš, M. Hint, V. Kalda, R. Karemäe, K. Komissarov, V. Kuik, M. Kõiv, E. Link, L. Kärk, A. Lõhmus, J. Lõhmus ja T. Merisalu

  15. Pink Frilly Dresses and the Avoidance of All Things "Girly": Children's Appearance Rigidity and Cognitive Theories of Gender Development

    Science.gov (United States)

    Halim, May Ling; Ruble, Diane N.; Tamis-LeMonda, Catherine S.; Zosuls, Kristina M.; Lurye, Leah E.; Greulich, Faith K.

    2014-01-01

    Many young children pass through a stage of gender appearance rigidity; girls insist on wearing dresses, often pink and frilly, whereas boys refuse to wear anything with a hint of femininity. In 2 studies, we investigated the prevalence of this apparent hallmark of early gender development and its relation to children's growing identification with…

  16. Instructional Exchange. Volume 2, Number 1-6, September 1990-March 1991.

    Science.gov (United States)

    Serafin, Ana Gil, Ed.

    1991-01-01

    This document consists of six issues of a newsletter that provides a forum for the sharing of research findings and instructional strategies by faculty of Western Michigan University. Issue Number 1 addresses writing in the Writing Across the Curriculum Program with notification of a faculty workshop, hints on how to encourage good writing, and a…

  17. Effects of a Progressive Prompting-Based Educational Game on Second Graders' Mathematics Learning Performance and Behavioral Patterns

    Science.gov (United States)

    Yang, Kai-Hsiang; Chu, Hui-Chun; Chiang, Li-Yu

    2018-01-01

    Game-based learning (GBL) has been proven to be an attractive learning model by many studies; however, scholars have pointed out that the effectiveness of game-based learning could be limited if proper learning strategies are not incorporated. Prompting is a strategy that plays the important role of providing hints and guidance in interactive…

  18. Philostr., Her. XXXV 9-10: ¿un testimonio de Eurísaces de Sófocles?

    Directory of Open Access Journals (Sweden)

    Miryam Librán Moreno

    2005-06-01

    Full Text Available Philostr. Her.. XXXV 9-10 may preserve hints of a rhesis from Sophocles' Eurysaces. Taking that as a departure point, a reconstruction of the general lines of this play is attempted from the evidence supplied by Accius, Pacuvius and Justin, as interpreted through the narrative pattern evinced in Oedipus at Colonus.

  19. Human Performance on Insight Problem Solving: A Review

    Science.gov (United States)

    Chu, Yun; MacGregor, James N.

    2011-01-01

    The article provides a review of recent research on insight problem-solving performance. We discuss what insight problems are, the different types of classic and newer insight problems, and how we can classify them. We also explain some of the other aspects that affect insight performance, such as hints, analogs, training, thinking aloud, and…

  20. Poly(N-isopropylacrylamide)-SiO2 nanocomposites interpenetrated by starch: Stimuli-responsive hydrogels with attractive tensile properties

    Czech Academy of Sciences Publication Activity Database

    Depa, Katarzyna; Strachota, Adam; Šlouf, Miroslav; Brus, Jiří

    2017-01-01

    Roč. 88, March (2017), s. 349-372 ISSN 0014-3057 R&D Projects: GA MŠk(CZ) LD14010 Grant - others:European Commission(XE) COST Action MP1202 HINT Institutional support: RVO:61389013 Keywords : PNIPAm hydrogel * starch * silica Subject RIV: CD - Macromolecular Chemistry OBOR OECD: Polymer science Impact factor: 3.531, year: 2016

  1. Get Kids Moving: Simple Activities To Build Gross-Motor Skills.

    Science.gov (United States)

    Texas Child Care, 2003

    2003-01-01

    Highlights the importance of activities to build gross motor skills and provides hints for encouraging such activities. Specific areas of activities presented are: (1) running and jumping; (2) music games; (3) action games; (4) races; (5) bed sheets or parachutes; (6) hula hoops; (7) balls; (8) batting; (9) balance; and (10) creative movement. (SD)

  2. Tasting Wine: A Learning Experience

    Science.gov (United States)

    King, Tanya J.; Donaldson, Jilleen A.; Harry, Emma

    2012-01-01

    This paper describes a field trip by senior undergraduate anthropology students to a local winery, where they participated in a wine-tasting class with winery staff. In response to explicit hints from a wine-tasting facilitator, and more subtle cues from the cultural capital embedded in their surroundings and the winery staff, the students…

  3. Environmental technology manual. Eisenmann Umwelttechnik

    Energy Technology Data Exchange (ETDEWEB)

    1983-01-01

    One part of the manual is dedicated to the removal of air pollution in the industrial sector, a conspectus of the bases of waste air cleaning is followed by explanations on modern cleaning methods and the pertaining installations. Under the catchword ''practice of waste air cleaning'' solution examples from the most different industrial sectors are presented, hints for planning, operation and maintenance given and some important characteristic data summed up in tables. The chapter on waste water addresses first of all operating personnel from industry and the service sector, providing aids to that group for the solution of waste water problems. A brief conspectus on the bases of waste water treatment is followed by a detailed description of the cleaning methods in use today and the pertaining installations. After practical examples and hints for operating and maintenance of waste water plants, tables on chemicals, pollutants and discharge conditions are given. The technology ''energy from waste material'' concentrates on the utilization of combustible wastes for energy production. The following possibilities are at hand: combustion, pyrolysis, and gasification.

  4. MHD equilibrium and pressure driven instability in L=1 heliotron plasmas

    International Nuclear Information System (INIS)

    Nakamura, Y.; Suzuki, Y.; Yamagishi, O.; Kondo, K.; Nakajima, N.; Hayashi, T.; Monticello, D.A.; Reiman, A.H.

    2003-01-01

    Free boundary MHD equilibrium properties of Heliotron J are investigated by VMEC, HINT and PIES codes, and ideal MHD stability properties are studied by the Mercier criterion, the ballooning mode equation and the CAS3D global stability code. It is shown by the equilibrium calculations that the change of the plasma boundary shape is substantial in a low shear helical system even if the beta is relatively low. Preliminary comparison between PIES results and HINT results shows that the beta value at which the magnetic island begin to be perceptible is almost the same in both codes, but the island width seems to be different. From the stability analysis, good correlation is found between local and global analyses for the three dimensional(3D) or helical ballooning mode whose mode structure shows strong poloidal and toroidal mode (helical mode) coupling. In the helical ballooning mode, the Eigenmode is localized within a flux tube. It is also found that the positive shear of the rotational transform is favorable for the 3D ballooning mode stability in a low shear helical system. (author)

  5. BrabA.11339.a: anomalous diffraction and ligand binding guide towards the elucidation of the function of a ‘putative β-lactamase-like protein’ from Brucella melitensis

    International Nuclear Information System (INIS)

    Abendroth, Jan; Sankaran, Banumathi; Edwards, Thomas E.; Gardberg, Anna S.; Dieterich, Shellie; Bhandari, Janhavi; Napuli, Alberto J.; Van Voorhis, Wesley C.; Staker, Bart L.; Myler, Peter J.; Stewart, Lance J.

    2011-01-01

    The structure of a β-lactamase-like protein from B. melitensis was solved independently using two data sets with anomalous signal. Anomalous Fourier maps could confirm the identity of two metal ions in the active site. AMP-bound and GMP-bound structures provide hints to the possible function of the protein. The crystal structure of a β-lactamase-like protein from Brucella melitensis was initially solved by SAD phasing from an in-house data set collected on a crystal soaked with iodide. A high-resolution data set was collected at a synchroton at the Se edge wavelength, which also provided an independent source of phasing using a small anomalous signal from metal ions in the active site. Comparisons of anomalous peak heights at various wavelengths allowed the identification of the active-site metal ions as manganese. In the native data set a partially occupied GMP could be identified. When co-crystallized with AMPPNP or GMPPNP, clear density for the hydrolyzed analogs was observed, providing hints to the function of the protein

  6. The analysis of linear partial differential operators I distribution theory and Fourier analysis

    CERN Document Server

    Hörmander, Lars

    2003-01-01

    The main change in this edition is the inclusion of exercises with answers and hints. This is meant to emphasize that this volume has been written as a general course in modern analysis on a graduate student level and not only as the beginning of a specialized course in partial differen­ tial equations. In particular, it could also serve as an introduction to harmonic analysis. Exercises are given primarily to the sections of gen­ eral interest; there are none to the last two chapters. Most of the exercises are just routine problems meant to give some familiarity with standard use of the tools introduced in the text. Others are extensions of the theory presented there. As a rule rather complete though brief solutions are then given in the answers and hints. To a large extent the exercises have been taken over from courses or examinations given by Anders Melin or myself at the University of Lund. I am grateful to Anders Melin for letting me use the problems originating from him and for numerous valuable comm...

  7. Evidence for extra radiation?

    DEFF Research Database (Denmark)

    Hamann, J.

    2012-01-01

    A number of recent analyses of cosmological data have reported hints for the presence of extra radiation beyond the standard model expectation. In order to test the robustness of these claims under different methods of constructing parameter constraints, we perform a Bayesian posterior-based and ......A number of recent analyses of cosmological data have reported hints for the presence of extra radiation beyond the standard model expectation. In order to test the robustness of these claims under different methods of constructing parameter constraints, we perform a Bayesian posterior...... during the marginalisation process, and we demonstrate that the effect is related to the fact that cosmic microwave background (CMB) data constrain N_eff only indirectly via the redshift of matter-radiation equality. Once present CMB data are combined with external information about, e.g., the Hubble...... parameter, the difference between the methods becomes small compared to the uncertainty of N_eff. We conclude that the preference of precision cosmological data for excess radiation is "real" and not an artifact of a specific choice of credible/confidence interval construction....

  8. Galaxies in the Universe - 2nd Edition

    Science.gov (United States)

    Sparke, Linda S.; Gallagher, John S., III

    2006-04-01

    This extensively illustrated book presents the astrophysics of galaxies since their beginnings in the early Universe. It has been thoroughly revised to take into account the most recent observational data, and recent discoveries such as dark energy. There are new sections on galaxy clusters, gamma ray bursts and supermassive black holes. The authors explore the basic properties of stars and the Milky Way before working out towards nearby galaxies and the distant Universe. They discuss the structures of galaxies and how galaxies have developed, and relate this to the evolution of the Universe. The book also examines ways of observing galaxies across the whole electromagnetic spectrum, and explores dark matter and its gravitational pull on matter and light. This book is self-contained and includes several homework problems with hints. It is ideal for advanced undergraduate students in astronomy and astrophysics. • Completely updated to take into account the latest observational data and theoretical concepts • Throughly revised with new sections on dark energy, gamma ray bursts, and central black holes in galaxies • Contains problems with hints to the solutions

  9. The perception of aquaculture on the Swedish West Coast

    DEFF Research Database (Denmark)

    Thomas, Jean-Baptiste E.; Nordström, Leif Jonas; Risén, Emma

    2017-01-01

    neutral responses. On the whole, respondents were favourable to the depicted scenario. Finally, it was found that the high-awareness group tended to be more supportive than the low or medium-awareness groups, hinting at the benefits of increasing awareness to reduce public aversion and to support...... a sustainable development of aquaculture on the Swedish West Coast....

  10. 1905. aasta eesti romaanis / Cornelius Hasselblatt

    Index Scriptorium Estoniae

    Hasselblatt, Cornelius, 1960-

    2015-01-01

    Vaadeldakse järgmisi romaane: Tammsaare, A. H. Tõde ja õigus III (1931, lühendatud variant 1968) ; Kärner, Jaan. Tõusev rahvas I-II (1936-1937) ; Kangro, Bernard. Kuma taevarannal (1950) ; Hint, Aadu. Tuuline rand I (1951, uus variant 1952) ; Krusten, Erni. Noorte südamed I-II (1954-1956) ; Ruben, Aarne. Volta annab kaeblikku vilet (2001)

  11. 1905. aasta Eesti romaanis / Cornelius Hasselblatt

    Index Scriptorium Estoniae

    Hasselblatt, Cornelius, 1960-

    2007-01-01

    Vaadeldakse järgmisi romaane: Tammsaare, A. H. Tõde ja õigus III (1931, lühendatud variant 1968) ; Kärner, Jaan. Tõusev rahvas I-II (1936-1937) ; Kangro, Bernard. Kuma taevarannal (1950) ; Hint, Aadu. Tuuline rand I (1951, uus variant 1952) ; Krusten, Erni. Noorte südamed I-II (1954-1956) ; Ruben, Aarne. Volta annab kaeblikku vilet (2001)

  12. Screen-Capturing System with Two-Layer Display for PowerPoint Presentation to Enhance Classroom Education

    Science.gov (United States)

    Lai, Yen-Shou; Tsai, Hung-Hsu; Yu, Pao-Ta

    2011-01-01

    This paper proposes a new presentation system integrating a Microsoft PowerPoint presentation in a two-layer method, called the TL system, to promote learning in a physical classroom. With the TL system, teachers can readily control hints or annotations as a way of making them visible or invisible to students so as to reduce information load. In…

  13. Teaching Environmental Ethics: Moral Considerations and Legislative Action

    Science.gov (United States)

    McGowan, Richard J.; Buttrick, Hilary G.

    2017-01-01

    As one of the first business ethics textbook states, by way of observation, "Custom, convention and the accepted courtesies of a society are not the foundation of ethics even though they provide valuable hints as to what men think… Law enshrines many of the ethical judgments of a society, but it is not coextensive with ethics" (Garrett,…

  14. Proceedings of the workshop on crystalline ion beams

    International Nuclear Information System (INIS)

    Hasse, R.W.; Hofmann, I.; Liesen, D.

    1989-04-01

    The workshop consisted of mainly invited and some contributed papers. More informal discussions took place in three working groups on the following topics: beam cooling techniques; diagnostics of crystalline beams; storage rings for crystalline beams. The present volume collects all papers as well as the summaries of the working groups. See hints under the relevant topics. (orig./HSI)

  15. Study of an ep facility for Europe

    International Nuclear Information System (INIS)

    Amaldi, U.

    1979-08-01

    These proceedings contains the lectures and discussion held in the named meeting. These concern machine problems, superconducting magnets, the search of new currents and new particles, large q 2 physics and hadron structure, small q 2 physics and photoproduction, as well as detectors for charged and neutral current events. See hints under the relevant topics. (HSI)

  16. "Telling Tales": The Teaching of American History through Storytelling

    Science.gov (United States)

    Sanchez, Tony R.; Mills, Randy K.

    2005-01-01

    The late novelist Walker Percy once argued that literature, especially fictional stories, has portrayed a clearer and far more cohesive picture of the human condition than any of the social sciences, including history. His ideas hint at the possibility of conceptualizing the American experience as the story that it is and as a way of organizing…

  17. Investment horizons : A time-dependent measure of asset performance

    OpenAIRE

    Ingve Simonsen; Anders Johansen; Mogens H. Jensen

    2005-01-01

    We review a resent {\\em time-dependent} performance measure for economical time series -- the (optimal) investment horizon approach. For stock indices, the approach shows a pronounced gain-loss asymmetry that is {\\em not} observed for the individual stocks that comprise the index. This difference may hint towards an synchronize of the draw downs of the stocks.

  18. Structural insight into the physical stability of amorphous Simvastatin dispersed in pHPMA: enhanced dynamics and local clustering as evidenced by solid-state NMR and Raman spectroscopy

    Czech Academy of Sciences Publication Activity Database

    Urbanová, Martina; Šturcová, Adriana; Kredatusová, Jana; Brus, Jiří

    2015-01-01

    Roč. 478, č. 2 (2015), s. 464-475 ISSN 0378-5173 R&D Projects: GA ČR(CZ) GA14-03636S; GA MŠk(CZ) LD14010 Grant - others:European Commission(XE) COST Action MP1202 HINT Institutional support: RVO:61389013 Keywords : solid dispersions * simvastatin * pharmaceuticals Subject RIV: CD - Macromolecular Chemistry Impact factor: 3.994, year: 2015

  19. Searching for Variables and Models to Investigate Mediators of Learning from Multiple Representations

    Science.gov (United States)

    Rau, Martina A.; Scheines, Richard

    2012-01-01

    Although learning from multiple representations has been shown to be effective in a variety of domains, little is known about the mechanisms by which it occurs. We analyzed log data on error-rate, hint-use, and time-spent obtained from two experiments with a Cognitive Tutor for fractions. The goal of the experiments was to compare learning from…

  20. Fotofilm - hall ala või sümbioos? / Greta Varts

    Index Scriptorium Estoniae

    Varts, Greta, 1986-

    2011-01-01

    Tallinna Fotokuu raames 14. okt.-l Tallinnas kinos Sõprus toimunud esimesest Eesti fotofilmide festivalist, kuraatorid Anna Hints ja Alis Mäesalu. Kunstnik Liina Siibi ja Saksa fotofilmi veterani Gusztáv Hámosi ettekannetest. Rahvusvahelisest fotofilmi konkursist "Ajatu lugu", mille võitis Anu-Laura Tuttelberg. Gusztáv Hámosi kureeritud ning tema osalusel valminud Saksa parimate fotofilmide valikust

  1. User modelling for motivational systems : the affective and the rational routes to persuasion

    NARCIS (Netherlands)

    Grasso, F.; Ham, J.R.C.; Masthoff, J.F.M.

    2011-01-01

    The idea that a computer system could be used to motivate people to perform a certain task on the basis of a user model is certainly not novel. As early as the 80s, intelligent tutoring systems would encourage students to learn by means of tailored feedback and hints [24], and in the 90s patient

  2. JPRS Report, Soviet Union, Political Affairs.

    Science.gov (United States)

    1989-10-03

    irresponsible, nebulous hints at the illness of Lenin, the hasty administration by I. V. Stalin (who, by the way, was not yet in a primary position of...doma" [Passions of a House in Bukhara] and "Cherepakha Tarazi" [The Turtle of Taraz]—could the author get published in his native Tashkent at one time

  3. Double Beta Decay Experiments

    International Nuclear Information System (INIS)

    Piepke, A.

    2005-01-01

    The experimental observation of neutrino oscillations and thus neutrino mass and mixing gives a first hint at new particle physics. The absolute values of the neutrino mass and the properties of neutrinos under CP-conjugation remain unknown. The experimental investigation of the nuclear double beta decay is one of the key techniques for solving these open problems

  4. Our Documents: A National Initiative on American History, Civics, and Service. Teacher Sourcebook, Volume II

    Science.gov (United States)

    Mazzenga, Maria, Ed.; McCullough, Julie, Ed.

    2003-01-01

    What do Matthew Brady, Carrie Chapman Catt, Ansel Adams, Orson Welles, and J. Howard Miller have to do with the 100 milestone documents? A few hints: Matthew Brady created the first photographic documentation of a war. Carrie Chapman Catt was the president of the National American Woman Suffrage Association in 1920. Orson Welles produced plays for…

  5. Form factors and charge radii in a quantum chromodynamics ...

    Indian Academy of Sciences (India)

    ... parent compared to the linear parent. Also, the analysis leads to a lower as well as upper bounds on the four-momentum transfer 2, hinting at a workable range of 2 within this approach, which may be useful in future experimental analyses. Comparison of both the options shows that the linear parent is the better option.

  6. Homophobic Slurs and Public Apologies: The Discursive Struggle over "Fag/Maricon" in Public Discourse

    Science.gov (United States)

    Cashman, Holly R.

    2012-01-01

    A handful of recent incidents hints at an ideological struggle over the use of the English word "fag(got)" and the Spanish word "maricon" in public discourse. This article examines the discursive and ideological struggle over the terms through the comparison of two cases in which Spanish/English bilingual Latinos in the U. S. use what might be…

  7. Rules of the Game for Women

    Science.gov (United States)

    Canty, Becky

    2005-01-01

    In "Play Like a Man, Win Like a Woman," Gail Evans' matter-of-fact directness contributes so many helpful hints about success that women need to learn. Playing to their strengths and characteristics as women is important to enhance their professional success. In the author's working life as a superintendent (which included three years as a theatre…

  8. Moving and Being Moved: Implications for Practice.

    Science.gov (United States)

    Kretchmar, R. Scott

    2000-01-01

    Uses philosophical writings, a novel about baseball, and a nonfiction work on rowing to analyze levels of meaning in physical activity, showing why three popular methods for enhancing meaning have not succeeded and may have moved some students away from deeper levels of meaning. The paper suggests that using hints taken from the three books could…

  9. Women and Computers: Effects of Stereotype Threat on Attribution of Failure

    Science.gov (United States)

    Koch, Sabine C.; Muller, Stephanie M.; Sieverding, Monika

    2008-01-01

    This study investigated whether stereotype threat can influence women's attributions of failure in a computer task. Male and female college-age students (n = 86, 16-21 years old) from Germany were asked to work on a computer task and were hinted beforehand that in this task, either (a) men usually perform better than women do (negative threat…

  10. Correct measurement of RF-exposure, caused by modern broadband radio systems; Korrekte Erfassung der Immissionen von modernen, breitbandigen Funksystemen

    Energy Technology Data Exchange (ETDEWEB)

    Wuschek, M. [Fachhochschule Deggendorf (Germany)

    2004-07-01

    Correct measurement of exposure, caused by modern broadband radio systems (UMTS, DAB, DVB-T, WLAN) requires special measuring-techniques. Looking at UMTS mobile communication systems as example, in this article the minimum requirements on measuring equipment will be shown. Additional hints were given, in which way an extrapolation of measurement field-levels to maximum installation power is possible. (orig.)

  11. "LinkedIn" for Accounting and Business Students

    Science.gov (United States)

    Albrecht, W. David

    2011-01-01

    LinkedIn is a social media application that every accounting and business student should join and use. LinkedIn is a database of 90,000,000 business professionals that enables each to connect and interact with their business associates. Five reasons are offered for why accounting students should join LinkedIn followed by 11 hints for use.

  12. Perception of environmental sounds by experienced cochlear implant patients

    Science.gov (United States)

    Shafiro, Valeriy; Gygi, Brian; Cheng, Min-Yu; Vachhani, Jay; Mulvey, Megan

    2011-01-01

    Objectives Environmental sound perception serves an important ecological function by providing listeners with information about objects and events in their immediate environment. Environmental sounds such as car horns, baby cries or chirping birds can alert listeners to imminent dangers as well as contribute to one's sense of awareness and well being. Perception of environmental sounds as acoustically and semantically complex stimuli, may also involve some factors common to the processing of speech. However, very limited research has investigated the abilities of cochlear implant (CI) patients to identify common environmental sounds, despite patients' general enthusiasm about them. This project (1) investigated the ability of patients with modern-day CIs to perceive environmental sounds, (2) explored associations among speech, environmental sounds and basic auditory abilities, and (3) examined acoustic factors that might be involved in environmental sound perception. Design Seventeen experienced postlingually-deafened CI patients participated in the study. Environmental sound perception was assessed with a large-item test composed of 40 sound sources, each represented by four different tokens. The relationship between speech and environmental sound perception, and the role of working memory and some basic auditory abilities were examined based on patient performance on a battery of speech tests (HINT, CNC, and individual consonant and vowel tests), tests of basic auditory abilities (audiometric thresholds, gap detection, temporal pattern and temporal order for tones tests) and a backward digit recall test. Results The results indicated substantially reduced ability to identify common environmental sounds in CI patients (45.3%). Except for vowels, all speech test scores significantly correlated with the environmental sound test scores: r = 0.73 for HINT in quiet, r = 0.69 for HINT in noise, r = 0.70 for CNC, r = 0.64 for consonants and r = 0.48 for vowels. HINT and

  13. The close of the year brings a hint that prices may be coming down

    International Nuclear Information System (INIS)

    Anon.

    1997-01-01

    A summary of financial data for the uranium spot market in December 1996 is provided. Price ranges for the restricted and unrestricted markets, conversion, and separative work are listed, and total market volume and new contracts are noted. Transactions made are briefly described. Deals made and pending in the spot concentrates, medium and long-term, conversion, and markets are listed for U.S. and non-U.S. buyers

  14. Basics of compounding: Tips and hints: powders, capsules, tablets, suppositories, and sticks, part 1.

    Science.gov (United States)

    Allen, Loyd V

    2014-01-01

    No matter the profession, professionals should never stop learning. This is especially true and important in the profession of compounding pharmacy. Compounding pharmacists are continuously faced with the challenge of finding new and inventive ways to assist patients with their individual and specific drug requirements. As compounding pharmacists learn, be it through formal continuing education or experience, they should be willing to share their knowledge with other compounders. In our goal of providing compounding pharmacists with additional knowledge to improve their skills in the art and practice of compounding, this article, which provides tips and hits on compounding with powders, capsules, tablets, suppositories, and sticks, represents the first in a series of articles to assist compounding pharmacists in the preparation of compounded medications.

  15. Hints on the Nature of Dark Matter from the Properties of Milky Way Satellites

    NARCIS (Netherlands)

    Anderhalden, D.; Schneider, A.; Macciò, A.V.; Diemand, J.; Bertone, G.

    2013-01-01

    The nature of dark matter is still unknown and one of the most fundamental scientific mysteries. Although successfully describing large scales, the standard cold dark matter model (CDM) exhibits possible shortcomings on galactic and sub-galactic scales. It is exactly at these highly non-linear

  16. Immunotherapeutic Potential of Oncolytic H-1 Parvovirus: Hints of Glioblastoma Microenvironment Conversion towards Immunogenicity.

    Science.gov (United States)

    Angelova, Assia L; Barf, Milena; Geletneky, Karsten; Unterberg, Andreas; Rommelaere, Jean

    2017-12-15

    Glioblastoma, one of the most aggressive primary brain tumors, is characterized by highly immunosuppressive microenvironment. This contributes to glioblastoma resistance to standard treatment modalities and allows tumor growth and recurrence. Several immune-targeted approaches have been recently developed and are currently under preclinical and clinical investigation. Oncolytic viruses, including the autonomous protoparvovirus H-1 (H-1PV), show great promise as novel immunotherapeutic tools. In a first phase I/IIa clinical trial (ParvOryx01), H-1PV was safe and well tolerated when locally or systemically administered to recurrent glioblastoma patients. The virus was able to cross the blood-brain (tumor) barrier after intravenous infusion. Importantly, H-1PV treatment of glioblastoma patients was associated with immunogenic changes in the tumor microenvironment. Tumor infiltration with activated cytotoxic T cells, induction of cathepsin B and inducible nitric oxide (NO) synthase (iNOS) expression in tumor-associated microglia/macrophages (TAM), and accumulation of activated TAM in cluster of differentiation (CD) 40 ligand (CD40L)-positive glioblastoma regions was detected. These are the first-in-human observations of H-1PV capacity to switch the immunosuppressed tumor microenvironment towards immunogenicity. Based on this pilot study, we present a tentative model of H-1PV-mediated modulation of glioblastoma microenvironment and propose a combinatorial therapeutic approach taking advantage of H-1PV-induced microglia/macrophage activation for further (pre)clinical testing.

  17. Looking at learning communities with the appropriate glasses: hints and ideas from network sciences

    Directory of Open Access Journals (Sweden)

    Fabio Nascimbeni

    2013-02-01

    Full Text Available 0 0 1 229 1263 USAL 10 2 1490 14.0 Normal 0 21 false false false ES JA X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin-top:0cm; mso-para-margin-right:0cm; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0cm; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:Calibri; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-ansi-language:ES; mso-fareast-language:EN-US;} The level of network thinking within education – intended as the capacity to look at learning systems and communities by focussing on the relations among the involved actors (primarily teachers and learners and not only on the actors characteristics – is growing, with different speeds depending on the educational sector, but not at the pace needed to keep up with the increasingly network nature of our societies. We claim that educational research and practices should increase their capacity to look at learning communities through appropriate “networking-sensitive” glasses, and get equipped with tools and methods – such as Social network Analysis - to properly understand and support these networks. The application of Social Network Analysis to education, especially in the case of distance learning, can allow understanding the patterns of interactions between teachers and learners, and can facilitate the consolidation of new approaches to understand collaboration mechanisms. The paper presents and discusses - from a learning viewpoint - a brief overview of the main theoretical and practical contributions coming from Social Network Analysis – such as the “random graphs”, the “small-worlds” or the “weak-ties” theories – together with some general properties and dynamics of networks, believing that mastering these dynamics is extremely important for educational researchers and practitioners, when it comes to understanding and supporting meaningful collaborative learning.

  18. SPINS OF LARGE ASTEROIDS: A HINT OF A PRIMORDIAL DISTRIBUTION IN THEIR SPIN RATES

    Energy Technology Data Exchange (ETDEWEB)

    Steinberg, Elad; Sari, Re’em [The Hebrew University of Jerusalem, Jerusalem (Israel)

    2015-04-15

    The Asteroid Belt and the Kuiper Belt are relics from the formation of our solar system. Understanding the size and spin distribution of the two belts is crucial for a deeper understanding of the formation of our solar system and the dynamical processes that govern it. In this paper, we investigate the effect of collisions on the evolution of the spin distribution of asteroids and KBOs. We find that the power law nature of the impactors’ size distribution leads to a Lévy distribution of the spin rates. This results in a power law tail in the spin distribution, in stark contrast to the usually quoted Maxwellian distribution. We show that for bodies larger than 10 km, collisions alone lead to spin rates peaking at 0.15–0.5 revolutions per day. Comparing that to the observed spin rates of large asteroids (R > 50 km), we find that the spins of large asteroids, peaking at ∼1–2 revolutions per day, are dominated by a primordial component that reflects the formation mechanism of the asteroids. Similarly, the Kuiper Belt has undergone virtually no collisional spin evolution, assuming current densities. Collisions contribute a spin rate of ∼0.01 revolutions per day, thus the observed fast spin rates of KBOs are also primordial in nature.

  19. Hints on the Broad Line Region Structure of Quasars at High and Low Luminosities

    Directory of Open Access Journals (Sweden)

    Marziani Paola

    2011-09-01

    Full Text Available Quasars show a considerable spectroscopic diversity. However, the variety of quasar spectra at low redshifts is non-random: a principal component analysis applied to large samples customarily identifies two main eigenvectors. In this contribution we show that the range of quasar optical spectral properties observed at low-z and associated with the first eigenvector is preserved up to z ≈ 2 in a sample of high luminosity quasars. We also describe two major luminosity effects.

  20. Squint surgery in TED -- hints and fints, or why Graves' patients are difficult patients.

    Science.gov (United States)

    Nardi, M

    2009-01-01

    Endocrine ophthalmopathy is the most common cause of acute onset diplopia in middle aged or older individuals. Ocular muscle involvement is characterized by myositis followed by fibrosis: this causes a stiffness and a shortening of the muscles involved with restriction of ocular movements: so the impairment of rotation is due to a mechanical obstacle and not to a paresis. Prisms are rarely useful in relieving diplopia and the majority of symptomatic patients need squint surgery. Timing of surgery is very important and two considerations are to be kept in mind: first, the systemic disease must be in remission and the ocular deviation must be stable for at least six months; second, if more than one surgical procedure is needed for the ophthalmopathy, muscle surgery has its right place after orbital surgery and before lid surgery. Obviously dealing with restrictive disorders, surgery is based on weakening procedures of the affected muscles: identifying the affected muscles is of crucial importance and may be sometime difficult for the presence of misleading signs; great advances have been made in surgical technique with the development of adjustable sutures and of topical anesthesia. Prognosis is usually good with more than 80% of patients recovering a useful field of binocular single vision with one procedure and more than 90% with two or more procedures.

  1. On a Fairy's Wing: Hints of Fitzgerald in Hemingway's "The Butterfly and the Tank"

    OpenAIRE

    Plath, James

    2008-01-01

    Lorsque, encore en France, Ernest Hemingway compose « The Butterfly and the Tank », le souvenir de conduite outrancière des Fitzgerald à Paris et à Juan-les-Pins est certainement présent dans son esprit. Le nombre d’allusions à Scott et Zelda sont trop soulignées pour qu’il en soit autrement. La structure de cette nouvelle, avec un Hemingway qui tient le rôle habituel de correspondant aguerri confirme ce postulat.Hemingway s’est souvent montré critique par rapport aux lamentations de Fitzgera...

  2. Issue Brief #2: Metrics for Improving Cost Accountability (Hint: Not More Detailed Cost Accounting...)

    Science.gov (United States)

    Delta Project on Postsecondary Education Costs, Productivity and Accountability, 2009

    2009-01-01

    Most fiscal reporting focuses on revenues (whether or not they go to core purposes), tuition and fees, and financial aid. "How" the money is spent is something that remains shrouded in too much mystery. Several national efforts to address this problem have largely come to naught--probably because those common methodologies are simultaneously not…

  3. Johannes Hint : ühe XX sajandi ausa mehe tragöödia / Holger Kaljulaid

    Index Scriptorium Estoniae

    Kaljulaid, Holger

    2006-01-01

    Desintegraatori juhi Johannes Hindi tegevusest ning temaga seotud kohtuprotsessist meedias avaldatud materjalide ja arhiividokumentide põhjal. Vt. samas väljavõtteid: Vladimir Georg Karassev-Orgusaare mõtteavaldusest 1982. aasta jaanuaris RL-i stuudios Pariisis; Johhannes Hindi sõnavõtust NSV Liidu Riikliku Plaanikomitee (Gosplan) kolleegiumil 10. II 1981 ja tema tööst "Viimaseid mõtteid inimkonnale", 1985; Aleksander Kaelase mõtteavaldusest aprillis 1955 Ameerika Hääle saates; Nikolai Baibakovi, Gosplani kunagise juhi (1965-85) 2000. a. märtsis antud intervjuust

  4. Dark matter searches from the galaxy to the LHC - recent hints and coming progress

    CERN Multimedia

    CERN. Geneva

    2008-01-01

    We discuss the possible galactic positron excess and constraints on interpreting it as dark matter annihilation. We consider wino and higgsino wimps that provide the local relic density and a positron excess (which implies the relic density is non-thermal in origin and important consequences for cosmological history and underlying theories), comment on how to confirm and study these issues at LHC, and on the relation to direct detection experiments.

  5. Hints on the Lateralization of Dopamine Binding to D-1 Receptors in Rat Striatum

    Czech Academy of Sciences Publication Activity Database

    Franco, R.; Casadó-Anguera, V.; Muňoz, A.; Petrovič, Miloš; Navarro, G.; Moreno, E.; Lanciego, J. L.; Labandeira-García, J. L.; Cortés, A.; Casadó, V.

    2016-01-01

    Roč. 53, č. 8 (2016), s. 5436-5445 ISSN 0893-7648 Institutional support: RVO:67985823 Keywords : lateralization * basal ganglia * G-protein-coupled receptor dimer * dyskinesia * 6-hydroxydopamine Subject RIV: ED - Physiology Impact factor: 6.190, year: 2016

  6. How Parents Influence School Grades: Hints from a Sample of Adoptive and Biological Families

    Science.gov (United States)

    Johnson, Wendy; McGue, Matt; Iacono, William G.

    2007-01-01

    Using the biological and adoptive families in the Minnesota-based Sibling Interaction and Behavior Study, we investigated the associations among genetic and environmental influences on IQ, parenting, parental expectations for offspring educational attainment, engagement in school, and school grades. All variables showed substantial genetic…

  7. Olle Höök Lectureship 2015: The World Health Organization's paradigm shift and implementation of the International Classification of Functioning, Disability and Health in rehabilitation.

    Science.gov (United States)

    Stucki, Gerold

    2016-06-13

    The World Health Organization's (WHO) paradigm shift, implied by the launch of the International Classification of Functioning, Disability and Health (ICF), is inextricably entwined with the emergence of rehabilitation as a key health strategy of the 21st century. To enable health systems to scale up rehabilitation we must spearhead the implementation of the ICF in rehabilitation towards its system-wide implementation in the healthcare system at large. In this essay, based on the Olle Höök lecture 20151, it is argued that the launch of the ICF in 2001 represents a paradigm shift, as it has enabled the WHO to more comprehensively act on its mandate and has guided WHO policies to shape the health system in response to population functioning needs. It is shown that this paradigm shift has important implications for rehabilitation, including its conceptualization and scientific methods. A prerequisite for the system-wide implementation of the ICF in clinical practice, policy, and research, is the availability of practical tools that allow for the universal and standardized description of functioning. Finally, some reflections are presented on how we may foster the system-wide implementation of the ICF by applying approaches from the implementation sciences.

  8. Quality Assurance for a TLD Based Individual Monitoring Service (invited paper)

    Energy Technology Data Exchange (ETDEWEB)

    Julius, H.W.; Van Dijk, J.W.E. [Arnhem (Netherlands)

    1999-07-01

    Approved Individual Monitoring Services should, in addition to complying with specific national performance requirements, also have implemented a quality assurance (QA) and quality control (QC) programme as an integral part of the operation. Essential elements of a QA/QC programme are discussed. Some practical hints and examples of QA practices are given, focussing on the application of thermoluminescence dosimetry. (author)

  9. Impact of the layout on the electrical characteristics of double-sided silicon 3D sensors fabricated at FBK

    Energy Technology Data Exchange (ETDEWEB)

    Povoli, M., E-mail: povoli@disi.unitn.it [Dipartimento di Ingegneria e Scienza dell' Informazione, Università di Trento, Via Sommarive, 14, I-38123 Povo di Trento (Italy); INFN, Sezione di Padova (Gruppo Collegato di Trento) (Italy); Bagolini, A.; Boscardin, M. [Fondazione Bruno Kessler, Centro per i Materiali e i Microsistemi (FBK-CMM), Via Sommarive, 18, I-38123 Povo di Trento, TN (Italy); Dalla Betta, G.-F. [Dipartimento di Ingegneria e Scienza dell' Informazione, Università di Trento, Via Sommarive, 14, I-38123 Povo di Trento (Italy); INFN, Sezione di Padova (Gruppo Collegato di Trento) (Italy); Giacomini, G.; Mattedi, F.; Vianello, E.; Zorzi, N. [Fondazione Bruno Kessler, Centro per i Materiali e i Microsistemi (FBK-CMM), Via Sommarive, 18, I-38123 Povo di Trento, TN (Italy)

    2013-01-21

    We report on experimental results and TCAD simulations addressing the impact of layout on the electrical characteristics of double-sided 3D diodes fabricated at Fondazione Bruno Kessler (FBK), Trento, Italy. Simulations are found to accurately reproduce the device characteristics, thus explaining the basic mechanisms governing the breakdown behavior and capacitance of different devices and providing useful hints for layout optimization.

  10. Impact of the layout on the electrical characteristics of double-sided silicon 3D sensors fabricated at FBK

    International Nuclear Information System (INIS)

    Povoli, M.; Bagolini, A.; Boscardin, M.; Dalla Betta, G.-F.; Giacomini, G.; Mattedi, F.; Vianello, E.; Zorzi, N.

    2013-01-01

    We report on experimental results and TCAD simulations addressing the impact of layout on the electrical characteristics of double-sided 3D diodes fabricated at Fondazione Bruno Kessler (FBK), Trento, Italy. Simulations are found to accurately reproduce the device characteristics, thus explaining the basic mechanisms governing the breakdown behavior and capacitance of different devices and providing useful hints for layout optimization.

  11. Analysis of the primary source term for meltdown accidents using MELCOR 1.8.2; Analyse des primaeren Quellterms bei Kernschmelzunfaellen mit MELCOR 1.8.2

    Energy Technology Data Exchange (ETDEWEB)

    Schmuck, P.

    1995-08-01

    The MELCOR code describing accident phenomena in the core and primary systems was used for source term calculations and - in the context of the MELCOR Cooperative Assessment Programme - for studying two-phase flows through components such as valves and chokes. Results of the latter studies in comparison to experiments gave hints for an improved calculation of momentum transfer between the phases. (orig.)

  12. Analysis of the primary source term for meltdown accidents using MELCOR 1.8.2

    International Nuclear Information System (INIS)

    Schmuck, P.

    1995-01-01

    The MELCOR code describing accident phenomena in the core and primary systems was used for source term calculations and - in the context of the MELCOR Cooperative Assessment Programme - for studying two-phase flows through components such as valves and chokes. Results of the latter studies in comparison to experiments gave hints for an improved calculation of momentum transfer between the phases. (orig.)

  13. XPS investigations on the UV-laser ablation mechanism of poly(ether imide)

    Energy Technology Data Exchange (ETDEWEB)

    Wambach, J; Kunz, T; Schnyder, B; Koetz, R; Wokaun, A [Paul Scherrer Inst. (PSI), Villigen (Switzerland)

    1999-08-01

    UV-Laser ablated samples of poly(ether imide) [Kapton{sup TM}] were studied with small-spot XPS. Applying fluences above the threshold level (0.167 J/cm{sup 2}) resulted in the expected behaviour of a decline of both nitrogen and oxygen. Below the threshold level a hint for an altered ablation mechanism was found. (author) 1 fig., 5 refs.

  14. Poly(N-isopropylacrylamide)-clay hydrogels: control of mechanical properties and structure by the initiating conditions of polymerization

    Czech Academy of Sciences Publication Activity Database

    Strachota, Beata; Hodan, Jiří; Matějka, Libor

    2016-01-01

    Roč. 77, April (2016), s. 1-15 ISSN 0014-3057 R&D Projects: GA ČR(CZ) GAP108/12/1459; GA MŠk(CZ) LD14010 Grant - others:European Commission(XE) COST Action MP1202 HINT Institutional support: RVO:61389013 Keywords : polymer- clay hydrogel * thermoresponsive hydrogel * nanocomposite Subject RIV: CD - Macromolecular Chemistry Impact factor: 3.531, year: 2016

  15. A New Kind of Biomaterials-Bullfrog Skin Collagen

    Institute of Scientific and Technical Information of China (English)

    He LI; Bai Ling LIU; Hua Lin CHEN; Li Zhen GAO

    2003-01-01

    Pepsin-soluble collagen was prepared from bullfrog skin and partially characterized. This study revealed interesting differences, such as molecular weight, amino acid composition, denaturation temperature (Td), in the frog skin collagen when compared to the known vertebrate collagens. This study gives hints that bullfrog skin can be a potential, safe alternative source of collagen from cattle for use in various fields.

  16. Using inventory data to determine the impact of drought on tree mortality

    Science.gov (United States)

    Greg C. Liknes; Christopher W. Woodall; Charles H. Perry

    2012-01-01

    Drought has been the subject of numerous recent studies that hint at an acceleration of tree mortality due to climate change. In particular, a recent global survey of tree mortality events implicates drought as the cause of quaking aspen mortality in Minnesota, USA in 2007. In this study, data from the Forest Inventory and Analysis program of the USDA Forest Service...

  17. Learning to Read and the Preschool Years

    Science.gov (United States)

    Wilson, Lorraine

    2012-01-01

    You have young preschool children. You think ahead to when they will begin school, and wonder what you might do to make it easy for your children to learn to read. This article offers some hints for parents and caregivers about learning to read: (1) Reading can begin at birth; (2) When reading aloud to an infant, make the experience a warm, loving…

  18. Magnetic interaction of positronium atoms measured by perturbed angular distribution in 3 gamma annihilation decay

    International Nuclear Information System (INIS)

    Ivanov, E.; Vata, I.; Plostinaru, D.; Catana, D.; Dudu, D.; Constantinescu, O.

    2003-01-01

    The Time Differential Perturbed Angular Distribution (TDPAD) method in connection with long-lived Positron Life-Time Spectroscopy (PLTS) have been used to observe 'quantum beat' spin oscillations of positronium atom in an external magnetic field. Our results offer an encouraging hint toward a new method of condensed matter investigation by PLTS. Similarities with Muonium Spin Rotation (μSR) method are suggested. (authors)

  19. Act Quickly! Seconds Count! Second Edition.

    Science.gov (United States)

    Ogden, Bob; Hayter, Roy, Ed.

    This booklet is designed to help hotel employees know what to do if a fire breaks out in the hotel. It also gives hints and suggestions that will help employees to reduce the risk of a fire occurring. Topics are as follows: an employee's responsibility if a fire breaks out; procedures to follow in the event of fire; mapping fire exits and escape…

  20. An introduction to modern cosmology

    CERN Document Server

    Liddle, Andrew

    2003-01-01

    A concise, accessible introduction to this exciting and dynamic subject.* Adopts an approach grounded in physics rather than mathematics.* Includes worked examples and student problems, along with hints for solving them and the numerical answers.* Many reviewers have commented that this is one of the best 'introductory undergraduate level' texts on the subject and they would all welcome a Second Edition.

  1. Halides of BET-TTF: novel hydrated molecular metals

    Energy Technology Data Exchange (ETDEWEB)

    Laukhina, E.; Ribera, E.; Vidal-Gancedo, J.; Canadell, E.; Veciana, J.; Rovira, C. [Universidad Autonoma de Barcelona, Bellaterra (Spain). Inst. de Ciencia de Materials; Khasanov, S.; Zorina, L.; Shibaeva, R. [Rossijskaya Akademiya Nauk, Chernogolovka (Russian Federation). Inst. Fiziki Tverdogo Tela; Laukhin, V. [Inst. of Problems of Chemical Physics, RAS, Chernogolovka (Russian Federation); Honold, M.; Nam, M.-S.; Singleton, J. [Clarendon Lab., Univ. of Oxford (United Kingdom)

    2000-01-07

    A hint of superconducting transition has been observed for the first time in a cation radical salt derived from bisethylenethio-tetrathiafulvalene (BET-TTF), the salt (BET-TTF){sub 2}Br.3H{sub 2}O. Here the synthesis, X-ray structure, and physical properties of two hydrated halides of BET-TTF that are isostructural and present stable metallic properties are described. (orig.)

  2. The great scientific revolutions of the 20. century; Les grandes revolutions scientifiques du 20. siecle

    Energy Technology Data Exchange (ETDEWEB)

    Parrochia, D. [Universite Paul Valery, Montpellier 3, 34 - Montpellier (France)

    1997-12-31

    Three great physical revolutions are studied here: the theory of relativity (general and restricted); the quantum mechanics (and its different interpretations); the theory of the determinist chaos (its pre-history as its applications). These three theories contribute to modify the answers that it is possible to bring to great metaphysical questions and to give a hint of a new philosophical landscape. (N.C.)

  3. Mäekalda kortermaja : Lucca küla, Tabasalu = Mäekalda Apartment Building : Lucca küla, Tabasalu / Oliver Alver

    Index Scriptorium Estoniae

    Alver, Oliver, 1977-

    2005-01-01

    Elamu kergust rõhutavad galeriid teepoolsel fassaadil, treppe katavad varikatused, pankranniku poolses küljes on avatav klaassein, mille taga on igal korteril veranda. Üldpind: 1071 mø, korterite arv: 8. Projekteerija: HTMd. Autor Oliver Alver. Konstruktor Eino Hint (Ehitusekspertiisibüroo). Projekt 2004, valmis 2005. Ill.: I, II ja III korruse plaan, 3 värv. välisvaadet

  4. Radiography of the chest and upper airway

    International Nuclear Information System (INIS)

    Sharko, G.A.; Wilmot, D.M.

    1987-01-01

    The techniques of radiography of the chest in all pediatric-age groups differ only slightly from those used in adult radiography. The technologist's principal challenge, however, relates to optimum handling of the patient with respect to positioning and radiation protection. The hints provided in this chapter should permit the conscientious radiographer to obtain high quality radiographs on all pediatric patients

  5. JPRS Report, East Europe

    Science.gov (United States)

    1988-08-22

    direct relationships, and agreements concerning 9 Hun- garian-Soviet joint enterprises have been reached. The Soviet Health Care Industry Scientific...organize and seek legaliza- tion. So, they are dropping hints about the Masturbation Society. It would support and advertize this inclination, which...appearing. The growing demand for healthful foods creates an excellent opportunity. Third, we must develop and intensify the processing of agricultural

  6. Environmental law

    International Nuclear Information System (INIS)

    Bender, B.; Sparwasser, R.

    1988-01-01

    Environmental law is discussed exhaustively in this book. Legal and scientific fundamentals are taken into account, a systematic orientation is given, and hints for further information are presented. The book covers general environmental law, plan approval procedures, protection against nuisances, atomic law and radiation protection law, water protection law, waste management law, laws on chemical substances, conservation law. (HSCH) [de

  7. Synthesis of conductive doubly filled poly(N-isopropylacrylamide)-polyaniline-SiO2 hydrogels

    Czech Academy of Sciences Publication Activity Database

    Depa, Katarzyna; Strachota, Adam; Šlouf, Miroslav; Brus, Jiří; Cimrová, Věra

    2017-01-01

    Roč. 244, June (2017), s. 616-634 ISSN 0925-4005 R&D Projects: GA MŠk(CZ) LD14010; GA ČR(CZ) GA13-26542S Grant - others:European Commission(XE) COST Action MP1202 HINT Institutional support: RVO:61389013 Keywords : PNIPAm hydrogel * polyaniline * silica Subject RIV: CD - Macromolecular Chemistry OBOR OECD: Polymer science Impact factor: 5.401, year: 2016

  8. Anomalies in Flavour physics

    CERN Document Server

    Chrzaszcz, Marcin Jakub

    2015-01-01

    LHCb is measuring more and more deviations in electroweak penguin measurements, both in the angular observables (like P5') and the branching fractions. Furthermore, there are strong hints of lepton universality breaking in semileptonic decays. This talk aims to present the results of these measurements and the implications for new physics. A result of a global fit will be presented.

  9. Single top t-channel

    CERN Document Server

    Faltermann, Nils

    2017-01-01

    The production of single top quarks allows to study the interplay of top quark physics and the electroweak sector of the standard model. Deviations from predictions can be a hint for physics beyond the standard model. The t-channel is the dominant production mode for single top quarks at the LHC. This talk presents the latest measurements from the ATLAS and CMS collaborations.

  10. Two-Quark Condensate Changes with Quark Current Mass

    International Nuclear Information System (INIS)

    Lu Changfang; Lue Xiaofu; Wu Xiaohua; Zhan Yongxin

    2009-01-01

    Using the Schwinger-Dyson equation and perturbation theory, we calculate the two-quark condensates for the light quarks u, d, strange quark s and a heavy quark c with their current masses respectively. The results show that the two-quark condensate will decrease when the quark mass increases, which hints the chiral symmetry may be restored for the heavy quarks.

  11. The great scientific revolutions of the 20. century

    International Nuclear Information System (INIS)

    Parrochia, D.

    1997-01-01

    Three great physical revolutions are studied here: the theory of relativity (general and restricted); the quantum mechanics (and its different interpretations); the theory of the determinist chaos (its pre-history as its applications). These three theories contribute to modify the answers that it is possible to bring to great metaphysical questions and to give a hint of a new philosophical landscape. (N.C.)

  12. [The so-called "chocolate cyst"--frequently misinterpreted as ovarian endometriosis?].

    Science.gov (United States)

    Christensen, B; Schindler, A E

    1996-09-01

    Limitation of morphological diagnostic and possible misinterpretations are shown in a patient with anamnestic ovarian endometriosis. In cases of "chocolate cysts" it is necessary to differentiate between ovarian endometriosis and functional cysts. Hints for the existence of a functional cyst are an atypical past history or perioperative findings. Biochemical analysis of the cyst fluid may lead to a correct diagnosis.

  13. Filaggrin gene mutations and the distribution of filaggrin in oral mucosa of patients with oral lichen planus and healthy controls.

    Science.gov (United States)

    Larsen, K R; Johansen, J D; Reibel, J; Zachariae, C; Rosing, K; Pedersen, A M L

    2017-05-01

    Lichen planus (LP) is a chronic inflammatory disease of unknown aetiology affecting the skin and oral mucosa. Oral lichenoid lesions (OLLs), like oral contact reactions, may resemble oral lichen planus (OLP) both clinically and histopathologically. As OLP and OLL are hyperkeratotic diseases and filaggrin is essential to keratinization, the distribution of filaggrin may be altered in these lesions. To investigate whether patients with OLP/OLL have (i) altered distribution of filaggrin in the oral mucosa; (ii) a higher incidence of mutations in the filaggrin gene (FLG); (iii) active dermatoses, apart from cutaneous LP, than healthy controls; and (iv) patients with OLP/OLL and a defect in the FLG have more widespread oral lesions and report more symptoms than OLP/OLL patients without a concomitant defect in the FLG. Forty-nine Caucasian patients (42 women and 7 men, mean age 61.0 ± 10.3 years), with symptomatic OLP, OLL or stomatitis, and 29 matched healthy controls underwent a clinical oral and dermatological examination, oral mucosal biopsy and filaggrin genotyping (testing for R2447X, R501X, 2282del4). Smear tests for Candida spp. were performed in all patients to exclude oral candidiasis. Immunohistochemistry were performed using poly- and monoclonal filaggrin antibodies. The immunoreactivity for filaggrin was significantly more intense in the oral mucosa in the patients with OLP/OLL compared with healthy controls (P = 0.000025). No difference was noted in the incidence of defects in the FLG and active dermatoses between patients and healthy controls. No difference was noted in extension and number of symptoms reported by patients with OLP/OLL with or without a concomitant defect in the FLG. OLP/OLL is associated with an altered distribution of filaggrin in the oral mucosa independently of defects in the FLG. Patients with OLP/OLL did not display more active dermatoses other than cutaneous LP when compared to healthy controls. © 2016 European Academy of

  14. Symptomatology and social inference: a theory of mind study of schizophrenia and psychotic affective disorder.

    Science.gov (United States)

    Marjoram, Dominic; Gardner, Clare; Burns, Jonathan; Miller, Patrick; Lawrie, Stephen M; Johnstone, Eve C

    2005-11-01

    There is evidence that certain patients with schizophrenia have deficits in theory of mind (ToM) capabilities. It is, however, unclear whether these are symptom or diagnosis-specific. A ToM hinting task was given to 15 patients with a DSM-IV diagnosis of schizophrenia, 15 patients with affective disorder and 15 healthy controls. Severity of the current psychopathology was measured using the Krawiecka standardised scale of psychotic symptoms (Krawiecka, Goldberg, & Vaughan, 1977); IQ was estimated via the Ammons and Ammons Quick Test (Ammons & Ammons, 1962). The group with schizophrenia performed significantly worse than the affective and control groups. Poor performance on the hinting task was found to be significantly related to the presence of positive symptoms (instead of negative ones) and specifically related to delusions and hallucinations. These findings remained when covariance for potentially confounding variables was applied. Individuals with high levels of delusions and hallucinations performed significantly worse on this ToM task, regardless of diagnosis, implying ToM impairment is not exclusive to schizophrenia but is evident in other forms of psychosis. Between-group analyses showed the schizophrenia group had a significantly poorer performance on this task than the others.

  15. The Micro-history of a world event: intention, perception and imagination at the Exposition universelle de 1867

    Directory of Open Access Journals (Sweden)

    Volker Barth

    2008-03-01

    Full Text Available Universal exhibitions are almost exclusively described as representations of an outside reality. The authenticity of the exhibits and the relation between the display and the real thing are put into consideration to investigate the political aims and ambitions of the organizers. However, the records of the spectators show that these were more likely to evaluate the objects according to other criteria. Here exhibitions reveal themselves as events that were not judged in the first place for their capacity to represent but for their ability to create. Visitors used them to develop pleasing mental images according to their individual and hedonistic motivations. In this sense, the exhibitions did not so much hint back to the outside than rather hint forward to an evolving imaginary inside the viewer. Thus, the paper focuses on the Paris Universal Exhibition of 1867 to explore how and to what purpose the spectators dealt with what they saw. My aim is to analyse exhibitions as independent imaginary worlds, which serve as starting points for creative cultural actions that are very little concerned with the realness of the display.

  16. Verification of the directivity index and other measures of directivity in predicting directional benefit

    Science.gov (United States)

    Dittberner, Andrew; Bentler, Ruth

    2005-09-01

    The relationship between various directivity measures and subject performance with directional microphone hearing aids was determined. Test devices included first- and second-order directional microphones. Recordings of sentences and noise (Hearing in Noise Test, HINT) were made through each test device in simple, complex, and anisotropic background noise conditions. Twenty-six subjects, with normal hearing, were administered the HINT test recordings, and directional benefit was computed. These measures were correlated to theoretical, free-field, and KEMAR DI values, as well as front-to-back ratios, in situ SNRs, and a newly proposed Db-SNR, wherein a predictive value of the SNR improvement is calculated as a function of the noise source incidence. The different predictive scores showed high correlation to the measured directional benefit scores in the complex (diffuse-like) background noise condition (r=0.89-0.97, pThe Db-SNR approach and the in situ SNR measures provided excellent prediction of subject performance in all background noise conditions (0.85-0.97, pthe predictive measures could account for the effects of reverberation on the speech signal (r=0.35-0.40, p<0.05).

  17. Testing the Presence of Multiple Photometric Components in Nearby Early-type Galaxies Using SDSS

    Energy Technology Data Exchange (ETDEWEB)

    Oh, Semyeong; Greene, Jenny E. [Department of Astrophysical Sciences, Princeton University, Princeton, NJ 08544 (United States); Lackner, Claire N., E-mail: semyeong@astro.princeton.edu [Kavli Institute for the Physics and Mathematics of the Universe (WPI), Todai Institutes for Advanced Study, the University of Tokyo, Kashiwa (Japan)

    2017-02-10

    We investigate two-dimensional image decomposition of nearby, morphologically selected early-type galaxies (ETGs). We are motivated by recent observational evidence of significant size growth of quiescent galaxies and theoretical development advocating a two-phase formation scenario for ETGs. We find that a significant fraction of nearby ETGs show changes in isophotal shape that require multi-component models. The characteristic sizes of the inner and outer component are ∼3 and ∼15 kpc. The inner component lies on the mass–size relation of ETGs at z ∼ 0.25–0.75, while the outer component tends to be more elliptical and hints at a stochastic buildup process. We find real physical differences between single- and double-component ETGs, with double-component galaxies being younger and more metal-rich. The fraction of double-component ETGs increases with increasing σ and decreases in denser environments. We hypothesize that double-component systems were able to accrete gas and small galaxies until later times, boosting their central densities, building up their outer parts, and lowering their typical central ages. In contrast, the oldest galaxies, perhaps due to residing in richer environments, have no remaining hints of their last accretion episode.

  18. Behaviour of organic materials in radiation environment

    CERN Document Server

    Tavlet, M

    2000-01-01

    Radiation effects in polymers are reminded together with the ageing factors. Radiation-ageing results are mainly discussed about thermosetting insulators, structural composites and cable-insulating materials. Some hints are given about high-voltage insulations, cooling fluids, organic scintillators and light-guides. Some parameters to be taken into account for the estimate of the lifetime of components in radiation environment are also shown. (23 refs).

  19. Insight into the cryopolymerization to form a poly(N-isopropylacrylamide)/clay macroporous gel: structure and phase evolution

    Czech Academy of Sciences Publication Activity Database

    Strachota, Beata; Matějka, Libor; Sikora, Antonín; Spěváček, Jiří; Konefal, Rafal; Zhigunov, Alexander; Šlouf, Miroslav

    2017-01-01

    Roč. 13, č. 6 (2017), s. 1244-1256 ISSN 1744-683X R&D Projects: GA ČR(CZ) GA13-23392S; GA MŠk(CZ) LD14010 Grant - others:European Commission(XE) COST Action MP1202 HINT Institutional support: RVO:61389013 Keywords : macroporous gels * nanocomposite cryogels * polymer-clay hydrogel Subject RIV: CD - Macromolecular Chemistry OBOR OECD: Polymer science Impact factor: 3.889, year: 2016

  20. How self-interactions can reconcile sterile neutrinos with cosmology.

    Science.gov (United States)

    Hannestad, Steen; Hansen, Rasmus Sloth; Tram, Thomas

    2014-01-24

    Short baseline neutrino oscillation experiments have shown hints of the existence of additional sterile neutrinos in the eV mass range. However, such neutrinos seem incompatible with cosmology because they have too large of an impact on cosmic structure formation. Here we show that new interactions in the sterile neutrino sector can prevent their production in the early Universe and reconcile short baseline oscillation experiments with cosmology.

  1. Superconducting Magnets

    CERN Multimedia

    CERN. Geneva

    2008-01-01

    Starting from the beam requirements for accelerator magnets, we will outline the main issues and the physical limitations for producing strong and pure magnetic fields with superconductors. The seminar will mainly focus on the magnets for the accelerator, and give some hints on the magnets for the experiments. Prerequisite knowledge: Basic knowledge of Maxwell equations, and linear optics for particle accelerators (FODO cell, beta functions).

  2. Meson-Meson molecules and compact four-quark states

    International Nuclear Information System (INIS)

    Vijande, J.; Valcarce, A.

    2010-01-01

    The physics of charm has become one of the best laboratories exposing the limitations of the naive constituent quark model and also giving hints into a more mature description of meson spectroscopy, beyond the simple quark-antiquark configurations. In this talk we review some recent studies of multiquark components in the charm sector and discuss in particular exotic and non-exotic four-quark systems.

  3. Details of Nazis' A-Bomb program surface

    CERN Multimedia

    Glanz, J

    2002-01-01

    Werner Heisenberg, leader of the Nazi atomic bomb program, revealed the projects existence to Niels Bohr in a meeting in Copenhagen in 1941. But contrary to several historical accounts of the meeting, Heisenberg never expressed moral qualms about building a bomb for Hitler nor hinted that he might be willing to sabotage the project, according to secret documents cited in a London newspaper yesterday (2 pages).

  4. e+e- collisions at 500 GeV: The physics potential

    International Nuclear Information System (INIS)

    Zerwas, P.M.

    1992-08-01

    In this report the physics potential of e + e - colliders in the first phase up to a c.m. energy of √s=500 GeV is assessed. A luminosity of L=10 33 cm -2 sec -1 has been assumed in general, leading to an integrated luminosity of about ∫L=10 fb -1 per year. See hints under the relevant topics. (orig./HSI)

  5. Searches for non-resonant new phenomena in final states with leptons and photons

    CERN Document Server

    Gonzalez Lopez, Oscar

    2017-01-01

    Some recent searches for hints of processes beyond the standard model performed by the CMS collaboration are presented. These focused on the detection of new phenomena more indirectly than the direct observation of a resonance indicating the presence of a new particle. No significant deviation from the standard model expectations have been observed and constraints for new physics have been set in several well-motivated scenarios.

  6. The challenges of communicating about risks

    International Nuclear Information System (INIS)

    Fisher, A.

    1992-01-01

    Managers in the nuclear industry and other potentially hazardous industries face tough but not insurmountable challenges when communicating about the risks for which they are responsible. Two types of information offer hints about successful risk communication: research within and across several disciplines and documentation of case studies. This presentation synthesizes research results and case study experience to define effective risk communication and suggests steps toward achieving it

  7. Liferay 6.x portal enterprise intranets cookbook

    CERN Document Server

    Filipowicz, Piotr

    2015-01-01

    If you are a Java developer or administrator with a technical background and want to install and configure Liferay Portal as an enterprise intranet, this is the book for you. In short, reusable recipes help you realize business goals as working features in Liferay. This book will also give you useful hints on how to easily improve the default functionality of the system and its performance.

  8. PDF uncertainties in precision electroweak measurements, including the W mass, in ATLAS

    CERN Document Server

    Cooper-Sarkar, Amanda; The ATLAS collaboration

    2015-01-01

    Now that the Higgs mass is known all the parameters of the SM are known- but with what accuracy? Precision EW measurements test the self-consistency of the SM- and thus can give hints of BSM physics. Precision measurements of $sin^2\\theta _W$ and the W mass are limited by PDF uncertainties This contribution discusses these uncertainties and what can be done to improve them.

  9. IBM DB2 97 Advanced Administration Cookbook

    CERN Document Server

    Neagu, Adrian

    2012-01-01

    This cookbook has recipes written in a simple, easy to understand format, with lots of screenshots and insightful tips and hints. If you are a DB2 Database Administrator who wants to understand and get hands on with the underlying aspects of database administration, then this book is for you. This book assumes that you have a basic understanding of DB2 database concepts.

  10. Recommendations for building and testing the next generation of gaseous detectors

    International Nuclear Information System (INIS)

    Schmidt, Bernhard

    2003-01-01

    This paper is the write-up of the very last talk of an interesting, exciting and exhausting workshop. It is not meant as yet another summary talk, but as the very personal view of the situation and recommendations for the future work. It attempts to give a few general hints and rules for the design, construction, development and operation of high rate gaseous detectors

  11. The graveyard and the Garden

    DEFF Research Database (Denmark)

    Bildsøe, Helle Schulz; Rahbek, Ulla

    2017-01-01

    and conflate into one overarching web that is the metropolis: there is a systemic network of control materialized in Montparnasse graveyard and an organic network out of control manifested in a community garden where people congregate to tell stories. Indeed, Dasgupta revisits Benjaminian storytelling...... as a global networking practice which, while locally contextualized in an impromptu garden in Paris, hints at an awareness of worldwide connectivity....

  12. Dead time effects from linear amplifiers and discriminators in single detector systems

    International Nuclear Information System (INIS)

    Funck, E.

    1986-01-01

    The dead-time losses originating from a linear amplifier combined with a discriminator for pulse-height selection are investigated. Measurements are carried out to determine the type of dead time represented by the amplifier-discriminator combination. The corrections involved by feeding the discriminator output pulses into an electronic module producing a blocking time are discussed and practical hints are given to reduce them. (orig.)

  13. Lood toimivad ajas / Laura Kuusk

    Index Scriptorium Estoniae

    Kuusk, Laura, 1982-

    2006-01-01

    Andres Härmi kureeritud näitusesari "Story" Tallinna Linnagaleriis: 14. IX-1. X "Story I: Katse ja eksitus. Monument massidele. Janna Holmstedt & Po Hagström"; 5.-22. X "Story II: 9. detsember 2005: minu märkmik. Tõnis Saadoja"; 26. X-12. XI "Story III: Aja sund. Minna Hint ja Jane Remm" ja 7.-31. XII "Story IV: Cinemagic Tour. Elsebeth Jorgensen"

  14. Measure and integration

    CERN Document Server

    Bercovici, Hari; Pearcy, Carl

    2016-01-01

    This book covers the material of a one year course in real analysis. It includes an original axiomatic approach to Lebesgue integration which the authors have found to be effective in the classroom. Each chapter contains numerous examples and an extensive problem set which expands considerably the breadth of the material covered in the text. Hints are included for some of the more difficult problems. .

  15. Targets for neutron beam spallation sources

    International Nuclear Information System (INIS)

    Bauer, G.S.

    1980-01-01

    The meeting on Targets for Neutron Beam Spallation Sources held at the Institut fuer Festkoerperforschung at KFA Juelich on June 11 and 12, 1979 was planned as an informal get-together for scientists involved in the planning, design and future use of spallation neutron sources in Europe. These proceedings contain the papers contributed to this meeting. For further information see hints under relevant topics. (orig./FKS)

  16. Masqued findings of the lung in children

    International Nuclear Information System (INIS)

    Fliegel, C.P.

    1982-01-01

    Masqued findings of the lung in children can cause grave diagnostic errors. A gamut list of typical pseudodiagnoses is given. Relevant cases are demonstrated as questions and answers. Practical hints how to reach a correct diagnosis are outlined. It is pointed out that initial standard films frequently have to be compleemented by special views to avoid false judgements, which could be harmful to the patient. (orig.)

  17. A Reality Check

    DEFF Research Database (Denmark)

    Skovsgaard, Morten; Albæk, Erik; Bro, Peter

    2013-01-01

    find that journalists’ role perceptions have substantial explanatory power in regard to how journalists implement the objectivity norm. The objectivity norm pervades the news production process by guiding journalists when they select, gather, and present the news, and the results give a hint about how...... the much studied journalistic role perceptions might affect the production process trough the objectivity norm and subsequently also the news content....

  18. High percentage of oral lichen planus and lichenoid lesion in oral squamous cell carcinomas.

    Science.gov (United States)

    Ruokonen, Hellevi M A; Juurikivi, Aino; Kauppila, Timo; Heikkinen, Anna Maria; Seppänen-Kaijansinkko, Riitta

    2017-08-01

    Oral lichen planus (OLP) and lichenoid lesions (OLL) are regarded as precursor lesions of oral squamous cell carcinoma (OSCC) with potential for malignant transformation. This potential is not clear due to difficulties in diagnosis of OLP and OLL. Our aim was therefore to evaluate previously identified OLP and OLL as precursor lesions in OSCC and to identify cancer related etiological factors such as smoking and alcohol consumption. We retrospectively reviewed all cases (total 323, comprising 164 females and 159 males) with OSCC treated at the Department of Oral and Maxillofacial Diseases and Surgery, Helsinki University Hospital during 2015. Confirmed by histopathological biopsy, 58 (17.9%) had OLP and 13 had OLL (4.0%) as precursor lesion. Patients with OLP were slightly older than those without it. OLP was more common in females than in males (p < .0001). TN class 1 tumors were more prevalent among patients with OLP or OLL (p = .006) and cancer relapses less common (p = .005). Smoking was less frequent in patients with OLP and OLL (p < .0001). Also alcohol abuse was less frequent among these patients (p < .001). Our findings confirm the importance of active follow-up of all patients with OLP and OLL even in patients who do not fit a traditional high-risk category for OSCC.

  19. Communicative-Pragmatic Typology of Irony-Effect with the Strategic Ambivalence within the English and Ukrainian Language Traditions

    Directory of Open Access Journals (Sweden)

    Hnatiuk Lubomira

    2016-12-01

    Full Text Available Background: The research of ambivalence is an actual problem of modern linguistics because of active promotion of Strategic Ambiguity as one of the key pragmatic categories on the way to understand the complexity of the concept of communicative intentions of the speaker. Generalization of conceptual and terminological findings in the Hinting Strategy of ironical utterances allows to develop the appropriate models of their practical application in the interpersonal interaction. Purpose: The purpose of the investigation is to determine the qualifying and classifying features of the irony-effect in order to demonstrate the importance of strategic ambiguity and propose a model for determining the strategically ambiguous communication. The main task of the article is to investigate the strategic ambivalence as one of the key categories of pragmatics toward understanding the complexity of the concept of intention in the speaker's communication and analyze different types of strategic ambiguity in the ironic utterances as well as the mechanisms of optimization of interpersonal interaction on the factual material of English and Ukrainian languages. Results: In the research the term strategic ambivalence refers to those communicative situations where interlocutors use ambiguity purposefully to accomplish their goals. Strategic ambiguity may be particularly useful in the interpersonal interaction. Under the circumstances of the Hinting Strategy communicative acts are often intentionally ambiguous since they allow different interpretations to coexist and therefore they are more effective in the interpersonal interaction. The communicative acts within ironical utterances are unclear and ambiguous. Although clarity is usually considered desirable for interpersonal communication, ambiguity may be more effective under the circumstances of the Hinting Stategy. Discussion: The strategic use of ambiguity minimizes the impolite speech acts. Another important

  20. Neural Correlates of Selective Attention With Hearing Aid Use Followed by ReadMyQuips Auditory Training Program.

    Science.gov (United States)

    Rao, Aparna; Rishiq, Dania; Yu, Luodi; Zhang, Yang; Abrams, Harvey

    The objectives of this study were to investigate the effects of hearing aid use and the effectiveness of ReadMyQuips (RMQ), an auditory training program, on speech perception performance and auditory selective attention using electrophysiological measures. RMQ is an audiovisual training program designed to improve speech perception in everyday noisy listening environments. Participants were adults with mild to moderate hearing loss who were first-time hearing aid users. After 4 weeks of hearing aid use, the experimental group completed RMQ training in 4 weeks, and the control group received listening practice on audiobooks during the same period. Cortical late event-related potentials (ERPs) and the Hearing in Noise Test (HINT) were administered at prefitting, pretraining, and post-training to assess effects of hearing aid use and RMQ training. An oddball paradigm allowed tracking of changes in P3a and P3b ERPs to distractors and targets, respectively. Behavioral measures were also obtained while ERPs were recorded from participants. After 4 weeks of hearing aid use but before auditory training, HINT results did not show a statistically significant change, but there was a significant P3a reduction. This reduction in P3a was correlated with improvement in d prime (d') in the selective attention task. Increased P3b amplitudes were also correlated with improvement in d' in the selective attention task. After training, this correlation between P3b and d' remained in the experimental group, but not in the control group. Similarly, HINT testing showed improved speech perception post training only in the experimental group. The criterion calculated in the auditory selective attention task showed a reduction only in the experimental group after training. ERP measures in the auditory selective attention task did not show any changes related to training. Hearing aid use was associated with a decrement in involuntary attention switch to distractors in the auditory selective

  1. Clinicopathologic Correlation of Oral Lichen Planus and Oral Lichenoid Lesions: A Preliminary Study

    Science.gov (United States)

    Mravak-Stipetić, Marinka; Lončar-Brzak, Božana; Bakale-Hodak, Iva; Seiwerth, Sven; Majstorović, Martina; Grce, Magdalena

    2014-01-01

    Oral lichen planus (OLP) and oral lichenoid lesions (OLL) are clinically and histologically similar lesions but their treatment planning and prognosis are different. The review of the literature indicates numerous criteria to distinguish these two lesions; however there is a lot of inconsistency. Thus, the aim of this study was to determine the correlation of histopathology and clinical OLP and OLL diagnosis and to clarify which histopathologic criteria could best distinguish these two diagnoses. A retrospective study showed that clinically diagnosed 92 OLPs and 14 OLLs have been confirmed histopathologically in 52.2% and 42.9% of cases, respectively. In addition, histopathology showed statistically significant more eosinophils (P < 0.0005), plasma cells (P < 0.0005), and granulocytes (P < 0.05) in OLL than OLP. To establish histopathological diagnosis of OLP and OLL it should be mandatory to define the type of cells in mononuclear infiltrate, which can be associated more accurately with clinical feature and patient history. Therefore, currently accepted diagnostic criteria for OLP and OLL should be modified and validated on a larger number of patients taking into account particular distinguishing histopathological features. PMID:25531004

  2. Differential metallothionein expression in oral lichen planus and amalgam-associated oral lichenoid lesions.

    Science.gov (United States)

    Mendes, G-G; Servato, J-P-S; Borges, F-C; Rosa, R-R; Siqueira, C-S; de Faria, P-R; Loyola, A-M; Cardoso, S-V

    2018-05-01

    Oral lichen planus (OLP) is a chronic inflammatory disease mediated by T cells, which manifests as reticular (white) or erosive (red) lesions, that are eventually painful. Oral lichenoid lesion (OLL) are distinguished from OLP by the presence of precipitating factors. The aim of this study was to evaluate whether the presence of metallothionein, which is involved in anti-apoptotic pathways and the anti-oxidative response, could serve as a differential diagnostic for OLP and OLL. We evaluated the expression of metallothionein in 40 cases of OLP and 20 cases of OLL using immunohistochemistry. White OLP has higher concentrations of metallothionein than red OLP in basal and parabasal layers. Moreover, metallothionein was more frequently observed in the cytoplasm and nuclei of basal cells in OLP patients compared to the same regions of OLL cases. Metallothionein levels are related to OLP severity and may contribute to a differential diagnosis between OLP and OLL.

  3. Renewable energy technologies. Plant concepts, applications and practical hints; Regenerative Energietechnologien. Anlagenkonzepte, Anwendungen und Praxistipps

    Energy Technology Data Exchange (ETDEWEB)

    Theiss, Eric

    2008-07-01

    This textbook provides a comprehensive outline of renewable energy technologies, prototypes and innovations in technical facilities that are ready for the market. On the basis of current catalogues of technical rules, directives and guidelines, possible system configurations are outlined for each technology which are explained by means of examples, a system description, and a list of reference projects. There is also a glossary for the various technologies and a list of contact addresses. The textbook addresses architects, engineers, energy consultants, and students. (orig.)

  4. PROFIBUS-DP. Fundamentals and hints for users; PROFIBUS-DP. Grundlagen, Tips und Tricks fuer Anwender

    Energy Technology Data Exchange (ETDEWEB)

    Popp, M.

    1998-04-01

    PROFIBUS-DP is one of the most common field buses for industrial communication. The author provides competent help in using this technology. He describes 32 of the most common errors found in certification tests and shows how they can be remedies. Fundamentals and enhancements of PROFIBUS-DP are presented. PROFIBUS-DP telegrams for data interpretation are discussed at length, as are extensive GSD files. Particular emphasis is given to the projecting and commissioning of a system and practical guides for installation. (orig.) [Deutsch] PROFIBUS-DP gehoert zu den am haeufigsten eingesetzten Feldbussen fuer die industrielle Kommunikation. Der Autor bietet in diesem umfassenden Werk kompetente Unterstuetzung bei der Anwendung dieser Feldbustechnik. Es werden 32 der haeufigsten Fehler, die bei Zertifizierungstests festgestellt wurden, beschrieben und Wege zu ihrer Behebung dargestellt. Die Grundlagen von PROFIBUS-DP werden erlaeutert und die PROFIBUS-Erweiterungen vorgestellt. PROFIBUS-DP-Telegramme zur Interpretation des Datenverkehrs werden genauso detailliert erklaert wie eine umfangreiche GSD-Datei. Ein besonderer Schwerpunkt ist die Projektierung und Inbetriebnahme einer Anlage und den praxisgerechten Aufbaurichtlinien gewidmet. (orig./GL)

  5. Smartphone Ownership Among US Adult Cigarette Smokers: 2014 Health Information National Trends Survey (HINTS) Data

    OpenAIRE

    Heffner, Jaimee L; Mull, Kristin E

    2017-01-01

    Background Despite increasing interest in smartphone apps as a platform for delivery of tobacco cessation interventions, no previous studies have evaluated the prevalence and characteristics of smokers who can access smartphone-delivered interventions. Objective To guide treatment development in this new platform and to evaluate disparities in access to smartphone-delivered interventions, we examined associations of smartphone ownership with demographics, tobacco use and thoughts about quitti...

  6. The infrared medium-deep survey. II. How to trigger radio AGNs? Hints from their environments

    Energy Technology Data Exchange (ETDEWEB)

    Karouzos, Marios; Im, Myungshin; Kim, Jae-Woo; Lee, Seong-Kook; Jeon, Yiseul; Choi, Changsu; Hong, Jueun; Hyun, Minhee; Jun, Hyunsung David; Kim, Dohyeong; Kim, Yongjung; Kim, Ji Hoon; Kim, Duho; Park, Won-Kee; Taak, Yoon Chan; Yoon, Yongmin [CEOU—Astronomy Program, Department of Physics and Astronomy, Seoul National University, Gwanak-gu, Seoul 151-742 (Korea, Republic of); Chapman, Scott [Department of Physics and Atmospheric Science, Dalhousie University, Halifax, Nova Scotia (Canada); Pak, Soojong [School of Space Research, Kyung Hee University, Yongin-si, Gyeonggi-do 446-701 (Korea, Republic of); Edge, Alastair, E-mail: mkarouzos@astro.snu.ac.kr [Department of Physics, University of Durham, South Road, Durham, DH1 3LE (United Kingdom)

    2014-12-10

    Activity at the centers of galaxies, during which the central supermassive black hole is accreting material, is nowadays accepted to be rather ubiquitous and most probably a phase of every galaxy's evolution. It has been suggested that galactic mergers and interactions may be the culprits behind the triggering of nuclear activity. We use near-infrared data from the new Infrared Medium-Deep Survey and the Deep eXtragalactic Survey of the VIMOS-SA22 field and radio data at 1.4 GHz from the FIRST survey and a deep Very Large Array survey to study the environments of radio active galactic nuclei (AGNs) over an area of ∼25 deg{sup 2} and down to a radio flux limit of 0.1 mJy and a J-band magnitude of 23 mag AB. Radio AGNs are predominantly found in environments similar to those of control galaxies at similar redshift, J-band magnitude, and (M{sub u} – M{sub r} ) rest-frame color. However, a subpopulation of radio AGNs is found in environments up to 100 times denser than their control sources. We thus preclude merging as the dominant triggering mechanism of radio AGNs. By fitting the broadband spectral energy distribution of radio AGNs in the least and most dense environments, we find that those in the least dense environments show higher radio-loudness, higher star formation efficiencies, and higher accretion rates, typical of the so-called high-excitation radio AGNs. These differences tend to disappear at z > 1. We interpret our results in terms of a different triggering mechanism for these sources that is driven by mass loss through winds of young stars created during the observed ongoing star formation.

  7. Riia Oja : maja läbi kolme korruse ja kahe tänava / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Tallinnas Uuel tänaval asuva eramu sisekujundus. Hoone on ehitatud 19. sajandi lõpul Pikal tänaval asuva elamu pesuköögiks. Sisearhitekt Riia Oja, kes projekteeris ka köögimööbli. vitraažid tegi Kaie Pärn. Renoveerimistöid teostas Hard Restauraator. Riia Oja ja omaniku kommentaarid. Ill.: korruste plaanid, 7 värv. vaadet

  8. Arukaotus haridus- ja teadussüsteemis : praegu toimuv tundub mõnes valdkonnas absurditeatrina / Mati Hint

    Index Scriptorium Estoniae

    Hint, Mati

    2004-01-01

    Autor avaldab pahameelt Eesti haridus- ja teadussüsteemis toimuva üle, hindamissüsteemi muutmise ning ülikoolides õpetatavate erialade õppekavade ja õppe- ja teadusliku töö taseme rahvusvahelise hindamise kriteeriumide kohta

  9. The Physiological Roles of Amyloid-β Peptide Hint at New Ways to Treat Alzheimer's Disease

    Directory of Open Access Journals (Sweden)

    Holly M. Brothers

    2018-04-01

    Full Text Available Amyloid-ß (Aß is best known as the misfolded peptide that is involved in the pathogenesis of Alzheimer's disease (AD, and it is currently the primary therapeutic target in attempts to arrest the course of this disease. This notoriety has overshadowed evidence that Aß serves several important physiological functions. Aß is present throughout the lifespan, it has been found in all vertebrates examined thus far, and its molecular sequence shows a high degree of conservation. These features are typical of a factor that contributes significantly to biological fitness, and this suggestion has been supported by evidence of functions that are beneficial for the brain. The putative roles of Aß include protecting the body from infections, repairing leaks in the blood-brain barrier, promoting recovery from injury, and regulating synaptic function. Evidence for these beneficial roles comes from in vitro and in vivo studies, which have shown that the cellular production of Aß rapidly increases in response to a physiological challenge and often diminishes upon recovery. These roles are further supported by the adverse outcomes of clinical trials that have attempted to deplete Aß in order to treat AD. We suggest that anti-Aß therapies will produce fewer adverse effects if the known triggers of Aß deposition (e.g., pathogens, hypertension, and diabetes are addressed first.

  10. Origin and evolution of retinoid isomerization machinery in vertebrate visual cycle: hint from jawless vertebrates.

    Science.gov (United States)

    Poliakov, Eugenia; Gubin, Alexander N; Stearn, Olivia; Li, Yan; Campos, Maria Mercedes; Gentleman, Susan; Rogozin, Igor B; Redmond, T Michael

    2012-01-01

    In order to maintain visual sensitivity at all light levels, the vertebrate eye possesses a mechanism to regenerate the visual pigment chromophore 11-cis retinal in the dark enzymatically, unlike in all other taxa, which rely on photoisomerization. This mechanism is termed the visual cycle and is localized to the retinal pigment epithelium (RPE), a support layer of the neural retina. Speculation has long revolved around whether more primitive chordates, such as tunicates and cephalochordates, anticipated this feature. The two key enzymes of the visual cycle are RPE65, the visual cycle all-trans retinyl ester isomerohydrolase, and lecithin:retinol acyltransferase (LRAT), which generates RPE65's substrate. We hypothesized that the origin of the vertebrate visual cycle is directly connected to an ancestral carotenoid oxygenase acquiring a new retinyl ester isomerohydrolase function. Our phylogenetic analyses of the RPE65/BCMO and N1pC/P60 (LRAT) superfamilies show that neither RPE65 nor LRAT orthologs occur in tunicates (Ciona) or cephalochordates (Branchiostoma), but occur in Petromyzon marinus (Sea Lamprey), a jawless vertebrate. The closest homologs to RPE65 in Ciona and Branchiostoma lacked predicted functionally diverged residues found in all authentic RPE65s, but lamprey RPE65 contained all of them. We cloned RPE65 and LRATb cDNAs from lamprey RPE and demonstrated appropriate enzymatic activities. We show that Ciona ß-carotene monooxygenase a (BCMOa) (previously annotated as an RPE65) has carotenoid oxygenase cleavage activity but not RPE65 activity. We verified the presence of RPE65 in lamprey RPE by immunofluorescence microscopy, immunoblot and mass spectrometry. On the basis of these data we conclude that the crucial transition from the typical carotenoid double bond cleavage functionality (BCMO) to the isomerohydrolase functionality (RPE65), coupled with the origin of LRAT, occurred subsequent to divergence of the more primitive chordates (tunicates, etc.) in the last common ancestor of the jawless and jawed vertebrates.

  11. Hints of Habitable Environments on Mars Challenge Our Studies of Mars-Analog Sites on Earth

    Science.gov (United States)

    desMarais, David J

    2009-01-01

    Life as we know it requires water with a chemical activity (alpha) >or approx.0.6 and sources of nutrients and useful energy. Some biota can survive even if favorable conditions occur only intermittently, but the minimum required frequency of occurrences is poorly understood. Recent discoveries have vindicated the Mars exploration strategy to follow the water. Mars Global Surveyor s Thermal Emission Spectrometer (TES) found coarse-grained hematite at Meridiani Planum. Opportunity rover confirmed this and also found evidence of ancient sulfate-rich playa lakes and near-surface groundwater. Elsewhere, TES found evidence of evaporitic halides in topographic depressions. But alpha might not have approached 0.6 in these evaporitic sulfate- and halide-bearing waters. Mars Express (MEX) and Mars Reconnaissance Orbiter (MRO) found extensive sulfate evaporites in Meridiani and Valles Marineris. MEX found phyllosilicates at several sites, most notably Mawrth Valles and Nili Fossae. MRO's CRISM near-IR mapper extended the known diversity and geographic distribution of phyllosilicates to include numerous Noachian craters. Phyllosilicates typically occur at the base of exposed ancient rock sections or in sediments in early Hesperian craters. It is uncertain whether the phyllosilicates developed in surface or subsurface aqueous environments and how long aqueous conditions persisted. Spirit rover found remarkably pure ferric sulfate, indicating oxidation and transport of Fe and S, perhaps in fumaroles or hot springs. Spirit also found opaline silica, consistent with hydrothermal activity. CRISM mapped extensive silica deposits in the Valles Marineris region, consistent with aqueous weathering and deposition. CRISM also found ultramafic rocks and magnesite at Nili Fossae, consistent with serpentinization, a process that can sustain habitable environments on Earth. The report of atmospheric methane implies subsurface aqueous conditions. A working hypothesis is that aqueous environments persisted in the near-subsurface for hundreds of millions of years and might exist even today. Studies of Mars-analog environments must better understand subsurface nonphotosynthetic ecosystems and their biosignatures in mafic and ultramafic terranes. Studies must determine minimum needs for water activity and energy and also establish survival limits when conditions that support active metabolism and propagation become progressively less frequent over time.

  12. The bioethics and law paradox: an argument to maintain separateness with a hint of togetherness.

    Science.gov (United States)

    Werren, Julia

    2007-10-01

    This article analyses how bioethics and law interact and work together. The first half of the article provides definitions of both ethics and bioethics. The article then considers a number of different bioethical standpoints to demonstrate the variance of views in relation to bioethics. In addition, the first half of the article focuses on the different regulatory possibilities in regard to bioethical contexts. This demonstrates that law is of central importance to bioethics. This part also shows that even though law and ethics are often used simultaneously to achieve bioethical goals, law and ethics cannot be used interchangeably. Thus, even though it is somewhat inevitable that law will be used in the pursuit of the goals of bioethics, bioethics and bioethical principle should not be merely a vehicle for law-makers to utilise. The second half of the article focuses on the issues of autonomy and consent to demonstrate how law and ethics have developed in one of the foundation areas of bioethics.

  13. Hints of an axion-like particle mixing in the GeV gamma-ray blazar data?

    Energy Technology Data Exchange (ETDEWEB)

    Mena, Olga [IFIC, Universidad de Valencia-CSIC, E-46071, Valencia (Spain); Razzaque, Soebur, E-mail: omena@ific.uv.es, E-mail: srazzaque@uj.ac.za [Department of Physics, University of Johannesburg, PO Box 524, Auckland Park 2006 (South Africa)

    2013-11-01

    Axion-Like Particles (ALPs), if exist in nature, are expected to mix with photons in the presence of an external magnetic field. The energy range of photons which undergo strong mixing with ALPs depends on the ALP mass, on its coupling with photons as well as on the external magnetic field and particle density configurations. Recent observations of blazars by the Fermi Gamma-Ray Space Telescope in the 0.1–300 GeV energy range show a break in their spectra in the 1–10 GeV range. We have modeled this spectral feature for the flat-spectrum radio quasar 3C454.3 during its November 2010 outburst, assuming that a significant fraction of the gamma rays convert to ALPs in the large scale jet of this blazar. Using theoretically motivated models for the magnetic field and particle density configurations in the kiloparsec scale jet, outside the broad-line region, we find an ALP mass m{sub a} ∼ (1−3)⋅10{sup −7} eV and coupling g{sub aγ} ∼ (1−3)⋅10{sup −10} GeV{sup −1} after performing an illustrative statistical analysis of spectral data in four different epochs of emission. The precise values of m{sub a} and g{sub aγ} depend weakly on the assumed particle density configuration and are consistent with the current experimental bounds on these quantities. We apply this method and ALP parameters found from fitting 3C454.3 data to another flat-spectrum radio quasar PKS1222+216 (4C+21.35) data up to 400 GeV, as a consistency check, and found good fit. We find that the ALP-photon mixing effect on the GeV spectra may not be washed out for any reasonable estimate of the magnetic field in the intergalactic media.

  14. Perceptual strategies of pigeons to detect a rotational centre--a hint for star compass learning?

    Directory of Open Access Journals (Sweden)

    Bianca Alert

    Full Text Available Birds can rely on a variety of cues for orientation during migration and homing. Celestial rotation provides the key information for the development of a functioning star and/or sun compass. This celestial compass seems to be the primary reference for calibrating the other orientation systems including the magnetic compass. Thus, detection of the celestial rotational axis is crucial for bird orientation. Here, we use operant conditioning to demonstrate that homing pigeons can principally learn to detect a rotational centre in a rotating dot pattern and we examine their behavioural response strategies in a series of experiments. Initially, most pigeons applied a strategy based on local stimulus information such as movement characteristics of single dots. One pigeon seemed to immediately ignore eccentric stationary dots. After special training, all pigeons could shift their attention to more global cues, which implies that pigeons can learn the concept of a rotational axis. In our experiments, the ability to precisely locate the rotational centre was strongly dependent on the rotational velocity of the dot pattern and it crashed at velocities that were still much faster than natural celestial rotation. We therefore suggest that the axis of the very slow, natural, celestial rotation could be perceived by birds through the movement itself, but that a time-delayed pattern comparison should also be considered as a very likely alternative strategy.

  15. Woodstove cookery. At home on the range

    Energy Technology Data Exchange (ETDEWEB)

    Cooper, J.

    1977-01-01

    The advantages and disadvantages of wood- or coal burning-stove cookery are discussed. The book serves as a guide or a manual. The stove, purchasing hints, and installation are described. Fuels, care, cleaning, building the fire, and uses are discussed. Recipes are included for breakfasts, soups and stews, main dishes, cheese and eggs, broiling and roasting, accompaniments, breads, desserts, dairy recipes, preserves, drying techniques, and homemade soap and other sundries. (MCW)

  16. Radiation-fresh for serving. 2. ed.

    International Nuclear Information System (INIS)

    Billen, G.

    1990-01-01

    The booklet sets out the most important facts on the subject of food irradiation. It provides information on the advantages and limits of this preservation process. What are the consequences of food irradiation for the consumer. What about the quality and labelling of irradiated food. What ecological problems are caused by the construction and operation of irradiation installations. Finally there are tips and hints for identifying irradiated food. (orig./HSCH) [de

  17. Conference Proceedings from the Annual Carnegie Cognition Symposium (10th) Held at Vail, Colorado on June 2-8, 1974: Cognition and Instruction

    Science.gov (United States)

    1976-05-15

    curious problem with most of the learning models in both cognitive psychology and artificial intellignece it that they are too single-minded in their... artificial intelli- gence can be considered a form of rational task analysis which is today being 3. TASK ANALYSIS IN INSTRUCTION 65 applied...store interrelating tasks, hints, manual references, etc. This store has been built usipg the associative language LEAP, a SAIL (Stanford Artificial

  18. Solar technology. The energy of the future: Bases, applications, perspectives. Solartechnik. Die Energie der Zukunft: Grundlagen, Anwendungen, Perspektiven

    Energy Technology Data Exchange (ETDEWEB)

    Tintrup, E.

    1991-01-01

    In recent years, the extensive use of fossil fuels has seriously aggravated environmental problems. They may be partially countered with the aid of renewable energy sources. This non-fiction book deals with the bases of solar technology in popular language. It also discusses in detail economic and political aspects associated with the launching of this technology. Finally, it provides hints for the self-construction of solar collectors and photovoltaic systems. (BWI).

  19. Max-Planck-Institute for Nuclear Physics. Annual report 1988

    International Nuclear Information System (INIS)

    Klapdor, H.V.; Jessberger, E.K.

    1989-01-01

    This annual report contains short notes and abstracts about the work performed at the named institute together with a list of publications and talks. The work concerns technical developments of accelerators and ion sources, experimental and theoretical studies on nuclear structure and reactions, high-energy physics, studies on meteorites and lunar rocks, comets, interplanetary and interstellar dust, interstellar dynamics, nuclear geology, and archaeometry. See hints under the relevant topics. (HSI)

  20. Identification of the First Riboflavin Catabolic Gene Cluster Isolated from Microbacterium maritypicum G10*

    OpenAIRE

    Xu, Hui; Chakrabarty, Yindrila; Philmus, Benjamin; Mehta, Angad P.; Bhandari, Dhananjay; Hohmann, Hans-Peter; Begley, Tadhg P.

    2016-01-01

    Riboflavin is a common cofactor, and its biosynthetic pathway is well characterized. However, its catabolic pathway, despite intriguing hints in a few distinct organisms, has never been established. This article describes the isolation of a Microbacterium maritypicum riboflavin catabolic strain, and the cloning of the riboflavin catabolic genes. RcaA, RcaB, RcaD, and RcaE were overexpressed and biochemically characterized as riboflavin kinase, riboflavin reductase, ribokinase, and riboflavin ...