WorldWideScience

Sample records for hint aili lilleorg

  1. Tõeliselt edukas on üksnes see juht, kes eraäri proovinud / Leela Lilleorg ; interv. Taivo Paju

    Index Scriptorium Estoniae

    Lilleorg, Leela

    2007-01-01

    Kümme aastat Estonian Airi arengus osalenud ning asepresidendiks jõudnud ja 2005. aastast lennufirmadele esindusteenust pakkuva firma Airline Management asutaja Leela Lilleorg oma töökogemustest. Vt. samas: Leela Lilleorg

  2. Aili Aarelaid-Tart väitles doktoriks

    Index Scriptorium Estoniae

    2007-01-01

    2006. aasta detsembris väitles Helsingi Ülikoolis doktoriks Tallinna Ülikooli dotsent Aili Aarelaid-Tart monograafiaga "Cultural Trauma and Life Stories". Tegemist on 148 kodueestlase, pagulaseestlase ja Eesti venelase eluloo võrdleval analüüsil põhineva uurimusega kultuuritraumadest, mille põhjuslik taust seostub II Maailmasõja järel Eesti okupeerimisega Nõukogude Liidu poolt ja Eesti Vabariigi taastamisega 1991. aastal

  3. Uus Ukraina : ELi kandidaat või taas Venemaa lähivälismaa? / Aili Ribulis

    Index Scriptorium Estoniae

    Ribulis, Aili

    2005-01-01

    Välispoliitika ekspert Aili Ribulis leiab, et suhtumises postrevolutsioonilisse Ukrainasse võiks Euroopa Liit võtta eeskuju NATO-st ja pakkuda konkreetseid tulevikuperspektiive. Euroopa Liidu naabruspoliitika

  4. Hilja Rüütli - Aili Helm : poliittinen vanki, sairaanhoitaja, kirjailija, ystävä / Anu Marttila

    Index Scriptorium Estoniae

    Marttila, Anu

    2009-01-01

    Isiklikke mälestusi. Ka Aili Helmi nime all ilmunud tetraloogiast, mille 3 osa kordustrükk ilmus ühiste kaante vahel 2009. a. Eesti Päevalehe ja ajakirja Akadeemia sarjas "Eesti lugu": Kuradil ei ole varju ; Vägivallamaa ; Režiim - see kõlab uhkelt

  5. Wiedemanni fond 10 / Jüri Valge, Piret Järvela, Liivi Heinla, Aili Kiin ; intervjueerinud Külliki Kask

    Index Scriptorium Estoniae

    2015-01-01

    Eraalgatuslik Wiedemanni fond toetab nii eesti keele õpilasuurimusi kui ka ülikooliõpinguid, sh magistri- ja doktoriõpet. Küsimustele vastavad Wiedemanni fondi 2015. aasta stipendiaadid, eesti keele ja kirjanduse õpetajad Piret Järvela Tallinna reaalkoolist, Liivi Heinla Kadrina keskkoolist ja Aili Kiin Viljandi gümnaasiumist. Küsitles Külliki Kask

  6. HINTS Puerto Rico: Final Report

    Science.gov (United States)

    This final report describes HINTS implementation in Puerto Rico. The report addresses sampling; staffing, training and management of data collection; calling protocol; findings from the CATI Operations, and sample weights.

  7. Active Learning Using Hint Information.

    Science.gov (United States)

    Li, Chun-Liang; Ferng, Chun-Sung; Lin, Hsuan-Tien

    2015-08-01

    The abundance of real-world data and limited labeling budget calls for active learning, an important learning paradigm for reducing human labeling efforts. Many recently developed active learning algorithms consider both uncertainty and representativeness when making querying decisions. However, exploiting representativeness with uncertainty concurrently usually requires tackling sophisticated and challenging learning tasks, such as clustering. In this letter, we propose a new active learning framework, called hinted sampling, which takes both uncertainty and representativeness into account in a simpler way. We design a novel active learning algorithm within the hinted sampling framework with an extended support vector machine. Experimental results validate that the novel active learning algorithm can result in a better and more stable performance than that achieved by state-of-the-art algorithms. We also show that the hinted sampling framework allows improving another active learning algorithm designed from the transductive support vector machine.

  8. Complexity hints for economic policy

    CERN Document Server

    Salzano, Massimo

    2007-01-01

    This volume extends the complexity approach to economics. This complexity approach is not a completely new way of doing economics, and that it is a replacement for existing economics, but rather the integration of some new analytic and computational techniques into economists’ bag of tools. It provides some alternative pattern generators, which can supplement existing approaches by providing an alternative way of finding patterns than be obtained by the traditional scientific approach. On this new kind of policy hints can be obtained. The reason why the complexity approach is taking hold now in economics is because the computing technology has advanced. This advance allows consideration of analytical systems that could not previously be considered by economists. Consideration of these systems suggested that the results of the "control-based" models might not extend easily to more complicated systems, and that we now have a method—piggybacking computer assisted analysis onto analytic methods—to start gen...

  9. Enhancing the Automatic Generation of Hints with Expert Seeding

    Science.gov (United States)

    Stamper, John; Barnes, Tiffany; Croy, Marvin

    2011-01-01

    The Hint Factory is an implementation of our novel method to automatically generate hints using past student data for a logic tutor. One disadvantage of the Hint Factory is the time needed to gather enough data on new problems in order to provide hints. In this paper we describe the use of expert sample solutions to "seed" the hint generation…

  10. Financial model calibration using consistency hints.

    Science.gov (United States)

    Abu-Mostafa, Y S

    2001-01-01

    We introduce a technique for forcing the calibration of a financial model to produce valid parameters. The technique is based on learning from hints. It converts simple curve fitting into genuine calibration, where broad conclusions can be inferred from parameter values. The technique augments the error function of curve fitting with consistency hint error functions based on the Kullback-Leibler distance. We introduce an efficient EM-type optimization algorithm tailored to this technique. We also introduce other consistency hints, and balance their weights using canonical errors. We calibrate the correlated multifactor Vasicek model of interest rates, and apply it successfully to Japanese Yen swaps market and US dollar yield market.

  11. Astrophysical hints of axion-like particles

    Science.gov (United States)

    Roncadelli, M.; Galanti, G.; Tavecchio, F.; Bonnoli, G.

    2015-01-01

    After reviewing three astrophysical hints of the existence of axion-like particles (ALPs), we describe in more detail a new similar hint involving flat spectrum radio quasars (FSRQs). Detection of FSRQs above about 20GeV pose a challenge to very-high-energy (VHE) astrophysics, because at those energies the ultraviolet emission from their broad line region should prevent photons produced by the central engine to leave the source. Although a few astrophysical explanations have been put forward, they are totally ad hoc. We show that a natural explanation instead arises within the conventional models of FSRQs provided that photon-ALP oscillations occur inside the source. Our analysis takes the FSRQ PKR 1222+206 as an example, and it looks tantalizing that basically the same choice of the free model parameters adopted in this case is consistent with those that provide the other three hints of the existence of ALPs.

  12. Eating Hints: Before, During, and After Cancer Treatment

    Science.gov (United States)

    ... Publications Reports Eating Hints: Before, during, and after Cancer Treatment Eating Hints is for people who are having or are about to have cancer treatment. Family and friends may also want to read ...

  13. Hants Hint - kõigi ihaldatud kaalukeel / Hants Hint ; interv. Erik Gamzejev

    Index Scriptorium Estoniae

    Hint, Hants

    2002-01-01

    Ilmunud ka: Severnoje Poberezhje : Laupäev 26. okt. lk. 3. Res Publica Ida-Viru piirkonna juht Hants Hint: me oleme põhimõtteliselt valmis kõigi poliitiliste jõududega koostööd tegema. Autor: Res Publica

  14. Experimental hint for gravitational CP violation

    Energy Technology Data Exchange (ETDEWEB)

    Gharibyan, Vahagn [Deutsches Elektronen-Synchrotron, Hamburg (Germany). MDI Group

    2016-01-15

    An equality of particle and antiparticle gravitational interactions holds in general relativity and is supported by indirect observations. Gravity dependence on rotation or spin direction is experimentally constrained only at low energies. Here a method based on high energy Compton scattering is developed to measure the gravitational interaction of accelerated charged particles. Within that formalism the Compton spectra measured at HERA rule out the positron's anti-gravity and hint for a gravitational CP violation around 13 GeV energies, at a maximal level of 1.3±0.2% for the charge and 0.68±0.09% for the space parity. A stronger gravitational coupling to left helicity electrons relative to right helicity positrons is detected.

  15. Experimental hint for gravitational CP violation

    International Nuclear Information System (INIS)

    Gharibyan, Vahagn

    2016-01-01

    An equality of particle and antiparticle gravitational interactions holds in general relativity and is supported by indirect observations. Gravity dependence on rotation or spin direction is experimentally constrained only at low energies. Here a method based on high energy Compton scattering is developed to measure the gravitational interaction of accelerated charged particles. Within that formalism the Compton spectra measured at HERA rule out the positron's anti-gravity and hint for a gravitational CP violation around 13 GeV energies, at a maximal level of 1.3±0.2% for the charge and 0.68±0.09% for the space parity. A stronger gravitational coupling to left helicity electrons relative to right helicity positrons is detected.

  16. Increased anxiety-related behaviour in Hint1 knockout mice.

    Science.gov (United States)

    Varadarajulu, Jeeva; Lebar, Maria; Krishnamoorthy, Gurumoorthy; Habelt, Sonja; Lu, Jia; Bernard Weinstein, I; Li, Haiyang; Holsboer, Florian; Turck, Christoph W; Touma, Chadi

    2011-07-07

    Several reports have implicated a role for the histidine triad nucleotide-binding protein-1 (Hint1) in psychiatric disorders. We have studied the emotional behaviour of male Hint1 knockout (Hint1 KO) mice in a battery of tests and performed biochemical analyses on brain tissue. The behavioural analysis revealed that Hint1 KO mice exhibit an increased emotionality phenotype compared to wildtype (WT) mice, while no significant differences in locomotion or general exploratory activity were noted. In the elevated plus-maze (EPM) test, the Hint1 KO animals entered the open arms of the apparatus less often than WT littermates. Similarly, in the dark-light box test, Hint1 KO mice spent less time in the lit compartment and the number of entries were reduced, which further confirmed an increased anxiety-related behaviour. Moreover, the Hint1 KO animals showed significantly more struggling and less floating behaviour in the forced swim test (FST), indicating an increased emotional arousal in aversive situations. Hint1 is known as a protein kinase C (PKC) interacting protein. Western blot analysis showed that PKCγ expression was elevated in Hint1 KO compared to WT mice. Interestingly, PKCγ mRNA levels of the two groups did not show a significant difference, implying a post-transcriptional PKCγ regulation. In addition, PKC enzymatic activity was increased in Hint1 KO compared to WT mice. In summary, our results indicate a role for Hint1 and PKCγ in modulating anxiety-related and stress-coping behaviour in mice. Copyright © 2011 Elsevier B.V. All rights reserved.

  17. An analytical model of the HINT performance metric

    Energy Technology Data Exchange (ETDEWEB)

    Snell, Q.O.; Gustafson, J.L. [Scalable Computing Lab., Ames, IA (United States)

    1996-10-01

    The HINT benchmark was developed to provide a broad-spectrum metric for computers and to measure performance over the full range of memory sizes and time scales. We have extended our understanding of why HINT performance curves look the way they do and can now predict the curves using an analytical model based on simple hardware specifications as input parameters. Conversely, by fitting the experimental curves with the analytical model, hardware specifications such as memory performance can be inferred to provide insight into the nature of a given computer system.

  18. New physics hints in B decays and collider outlook

    Indian Academy of Sciences (India)

    There are currently two hints for new physics involving CP violation in → transitions: ≡ - / ≠ 0, and difference in direct CP asymmetry Δ A K π ≡ A K + π 0 − A K + π ≠ 0 . We explore the two scenarious with a large and unique new CP phase in ← tansitions. Motivated by ≠ 0, we update on the ...

  19. Gaze-based hints during child-robot gameplay

    NARCIS (Netherlands)

    Mwangi, E.; Barakova, Emilia I.; Diaz, M.L.Z.; Mallofre, A.C.; Rauterberg, G.W.M.; Kheddar, A.; Yoshida, E.; Sam Ge, S.; Suzuki, K.; Cabibihan, J.J.; Eyssel, F.; He, H.

    2017-01-01

    This paper presents a study that examines whether gaze hints provided by a robot tutor influences the behavior of children in a card matching game. In this regard, we conducted a within-subjects experiment, in which children played a card game “Memory” in the presence of a robot tutor in two

  20. Observational Hints of a Pre--Inflationary Scale?

    CERN Document Server

    Gruppuso, A.

    2015-09-28

    We argue that the lack of power exhibited by cosmic microwave background (CMB) anisotropies at large angular scales might be linked to the onset of inflation. We highlight observational features and theoretical hints that support this view, and present a preliminary estimate of the physical scale that would underlie the phenomenon.

  1. A two-Higgs-doublet model facing experimental hints

    Directory of Open Access Journals (Sweden)

    Crivellin Andreas

    2016-01-01

    Full Text Available Physics beyond the Standard Model has so far eluded our experimental probes. Nevertheless, a number of interesting anomalies have accumulated that can be taken as hints towards new physics: BaBar, Belle, and LHCb have found deviations of approximately 3:8σ in B → Dτν and B → D*τν; the anomalous magnetic moment of the muon differs by about 3σ from the theoretic prediction; the branching ratio for τ → μνν is about 2σ above the Standard Model expectation; and CMS and ATLAS found hints for a non-zero decay rate of h → μτ at 2.6σ. Here we consider these processes within a lepton-specific two-Higgs doublet model with additional non-standard Yukawa couplings and show how (and which of these excesses can be accommodated.

  2. HINT computation of LHD equilibrium with zero rotational transform surface

    International Nuclear Information System (INIS)

    Kanno, Ryutaro; Toi, Kazuo; Watanabe, Kiyomasa; Hayashi, Takaya; Miura, Hideaki; Nakajima, Noriyoshi; Okamoto Masao

    2004-01-01

    A Large Helical Device equilibrium having a zero rotational transform surface is studied by using the three dimensional MHD equilibrium code, HINT. We find existence of the equilibrium but with formation of the two or three n=0 islands composing a homoclinic-type structure near the center, where n is a toroidal mode number. The LHD equilibrium maintains the structure, when the equilibrium beta increases. (author)

  3. [Peripheral vertigo versus central vertigo. Application of the HINTS protocol].

    Science.gov (United States)

    Batuecas-Caletrío, Ángel; Yáñez-González, Raquel; Sánchez-Blanco, Carmen; González-Sánchez, Enrique; Benito, José; Gómez, José Carlos; Santa Cruz-Ruiz, Santiago

    2014-10-16

    One of the most important dilemmas concerning vertigo in emergency departments is its differential diagnosis. There are highly sensitive warning signs in the examination that can put us on the path towards finding ourselves before a case of central vertigo. To determine how effective the application of the HINTS protocol is in the diagnosis of cerebrovascular accidents that mimics peripheral vertigo. We conducted a descriptive observation-based study on patients admitted to hospital with a diagnosis of acute vestibular syndrome in the emergency department. All the patients were monitored on a day-to-day basis until their symptoms improved, with information about nystagmus, the oculocephalic manoeuvre and the skew test. The results from the magnetic resonance imaging study were compared with the alteration of any of those three signs during the time the patient was hospitalised. Altogether 91 patients were examined, with a mean age of 55.8 years. A cerebrovascular accident was observed in eight cases. Of these (mean age: 71 years), in seven of them there were alterations in some of the HINTS signs, and in one case the study was normal (sensitivity: 0.88; specificity: 0.96). All of them had some vascular risk factor. Faced with a patient who visits the emergency department with an acute vestibular syndrome, a suitably directed examination is essential to be able to establish the differential diagnosis between peripheral and central pathology, since some cerebrovascular accidents can present with the appearance of acute vertigo. Applying a protocol like HINTS makes it possible to suspect the central pathology with a high degree of sensitivity and specificity.

  4. Tants valguse laval / Aili Ermel

    Index Scriptorium Estoniae

    Ermel, Aili

    2013-01-01

    Valgustid Milanos toimunud messil "Euroluce 2013". Mihkel Masso ja Johan Tali paberlennukitest inspireeritud laevalgustid "Hetk". Tarmo Luisu valgusti "Spider" ja valgustisari "Toila", Tõnis Vellama valgusti "Aero", Tõnis Vellama ja Kalju Palo seinavalgusti "Retro", Triin Kõivupuu ja Eva Prüüsi valgustisari "Lill"

  5. HINT-KB: The human interactome knowledge base

    KAUST Repository

    Theofilatos, Konstantinos A.

    2012-01-01

    Proteins and their interactions are considered to play a significant role in many cellular processes. The identification of Protein-Protein interactions (PPIs) in human is an open research area. Many Databases, which contain information about experimentally and computationally detected human PPIs as well as their corresponding annotation data, have been developed. However, these databases contain many false positive interactions, are partial and only a few of them incorporate data from various sources. To overcome these limitations, we have developed HINT-KB (http://150.140.142.24:84/Default.aspx) which is a knowledge base that integrates data from various sources, provides a user-friendly interface for their retrieval, estimates a set of features of interest and computes a confidence score for every candidate protein interaction using a modern computational hybrid methodology. © 2012 IFIP International Federation for Information Processing.

  6. Understanding Attention to Adaptive Hints in Educational Games: An Eye-Tracking Study

    Science.gov (United States)

    Conati, Cristina; Jaques, Natasha; Muir, Mary

    2013-01-01

    This paper presents a user study that investigates the factors affecting student attention to user-adaptive hints during interaction with an educational computer game. The study focuses on Prime Climb, an educational game designed to provide individualized support for learning number factorization skills in the form of textual hints based on a…

  7. Particle Swarm Optimization algorithms for geophysical inversion, practical hints

    Science.gov (United States)

    Garcia Gonzalo, E.; Fernandez Martinez, J.; Fernandez Alvarez, J.; Kuzma, H.; Menendez Perez, C.

    2008-12-01

    PSO is a stochastic optimization technique that has been successfully used in many different engineering fields. PSO algorithm can be physically interpreted as a stochastic damped mass-spring system (Fernandez Martinez and Garcia Gonzalo 2008). Based on this analogy we present a whole family of PSO algorithms and their respective first order and second order stability regions. Their performance is also checked using synthetic functions (Rosenbrock and Griewank) showing a degree of ill-posedness similar to that found in many geophysical inverse problems. Finally, we present the application of these algorithms to the analysis of a Vertical Electrical Sounding inverse problem associated to a seawater intrusion in a coastal aquifer in South Spain. We analyze the role of PSO parameters (inertia, local and global accelerations and discretization step), both in convergence curves and in the a posteriori sampling of the depth of an intrusion. Comparison is made with binary genetic algorithms and simulated annealing. As result of this analysis, practical hints are given to select the correct algorithm and to tune the corresponding PSO parameters. Fernandez Martinez, J.L., Garcia Gonzalo, E., 2008a. The generalized PSO: a new door to PSO evolution. Journal of Artificial Evolution and Applications. DOI:10.1155/2008/861275.

  8. New physics hints in Β decays and collider outlook

    International Nuclear Information System (INIS)

    Hou, George W.S.

    2006-01-01

    There are currently two hints for new physics involving CP violation in b →s transitions: ΔS ≡ S f - S J/ ψK ≠ 0, and difference in direct CP asymmetry ΔA Kπ ≡ A K + π 0 - A K + π - ≠0. We explore the two scenarios with a large and unique new CP phase in b s transitions. Motivated by ΔS ≠ 0, we update on the right-handed strange beauty squark sb 1R at TeV scale. Motivated by ΔA Kπ ≠ 0, we explore sequential fourth generation t and b quarks. Both scenarios can survive constraints such as SM level b→sγ, sll and Β s mixing, and predict sizable CP violation in Β s mixing. The fourth generation picture predicts sizable K L → π 0 νν. Direct search for sb R , b' and t' at hadronic colliders, such as Tevatron Run II and LHC, can complement further CP violation studies at these machines, as well as at the future Super Β factory. (author)

  9. HinT proteins and their putative interaction partners in Mollicutes and Chlamydiaceae

    Directory of Open Access Journals (Sweden)

    Hegemann Johannes H

    2005-05-01

    Full Text Available Background HinT proteins are found in prokaryotes and eukaryotes and belong to the superfamily of HIT proteins, which are characterized by an histidine-triad sequence motif. While the eukaryotic variants hydrolyze AMP derivates and modulate transcription, the function of prokaryotic HinT proteins is less clearly defined. In Mycoplasma hominis, HinT is concomitantly expressed with the proteins P60 and P80, two domains of a surface exposed membrane complex, and in addition interacts with the P80 moiety. Results An cluster of hitABL genes, similar to that of M. hominis was found in M. pulmonis, M. mycoides subspecies mycoides SC, M. mobile and Mesoplasma florum. RT-PCR analyses provided evidence that the P80, P60 and HinT homologues of M. pulmonis were polycistronically organized, suggesting a genetic and physical interaction between the proteins encoded by these genes in these species. While the hit loci of M. pneumoniae and M. genitalium encoded, in addition to HinT, a protein with several transmembrane segments, the hit locus of Ureaplasma parvum encoded a pore-forming protein, UU270, a P60 homologue, UU271, HinT, UU272, and a membrane protein of unknown function, UU273. Although a full-length mRNA spanning the four genes was not detected, amplification of all intergenic regions from the center of UU270 to the end of UU273 by RT-PCR may be indicative of a common, but unstable mRNA. In Chlamydiaceae the hit gene is flanked upstream by a gene predicted to encode a metal dependent hydrolase and downstream by a gene putatively encoding a protein with ARM-repeats, which are known to be involved in protein-protein interactions. In RT-PCR analyses of C. pneumoniae, regions comprising only two genes, Cp265/Cp266 and Cp266/Cp267 were able to be amplified. In contrast to this in vivo interaction analysis using the yeast two-hybrid system and in vitro immune co-precipitation revealed an interaction between Cp267, which contains the ARM repeats, Cp265, the

  10. Hint2, the mitochondrial nucleoside 5'-phosphoramidate hydrolase; properties of the homogeneous protein from sheep (Ovis aries) liver.

    Science.gov (United States)

    Bretes, Ewa; Wojdyła-Mamoń, Anna M; Kowalska, Joanna; Jemielity, Jacek; Kaczmarek, Renata; Baraniak, Janina; Guranowski, Andrzej

    2013-01-01

    Adenosine 5'-phosphoramidate (NH2-pA) is a rare natural nucleotide and its biochemistry and biological functions are poorly recognized. All organisms have proteins that may be involved in the catabolism of NH2-pA. They are members of the HIT protein family and catalyze hydrolytic splitting of NH2-pA to 5'-AMP and ammonia. At least five HIT proteins have been identified in mammals; however, the enzymatic and molecular properties of only Fhit and Hint1 have been comprehensively studied. Our study focuses on the Hint2 protein purified by a simple procedure to homogeneity from sheep liver mitochondrial fraction (OaHint2). Hint1 protein was also prepared from sheep liver (OaHint1) and the molecular and kinetic properties of the two proteins compared. Both function as homodimers and behave as nucleoside 5'-phosphoramidate hydrolases. The molecular mass of the OaHint2 monomer is 16 kDa and that of the OaHint1 monomer 14.9 kDa. Among potential substrates studied, NH2-pA appeared to be the best; the Km and kcat values estimated for this compound are 6.6 μM and 68.3 s⁻¹, and 1.5 μM and 11.0 s⁻¹ per natively functioning dimer of OaHint2 and OaHint1, respectively. Studies of the rates of hydrolysis of different NH2-pA derivatives show that Hint2 is more specific towards compounds with a P-N bond than Hint1. The thermostability of these two proteins is also compared.

  11. Interaction Networks: Generating High Level Hints Based on Network Community Clustering

    Science.gov (United States)

    Eagle, Michael; Johnson, Matthew; Barnes, Tiffany

    2012-01-01

    We introduce a novel data structure, the Interaction Network, for representing interaction-data from open problem solving environment tutors. We show how using network community detecting techniques are used to identify sub-goals in problems in a logic tutor. We then use those community structures to generate high level hints between sub-goals.…

  12. Pigeons (Columba livia) know when they will need hints: prospective metacognition for reference memory?

    Science.gov (United States)

    Iwasaki, Sumie; Watanabe, Sota; Fujita, Kazuo

    2018-03-01

    Despite their impressive cognitive abilities, avian species have shown less evidence for metacognition than mammals. We suspect that commonly used tasks such as matching to sample might be too demanding to allow metacognitive processing within birds' working memory. Here, we examined whether pigeons could control their behavior as a function of knowledge levels on a three-item sequence learning task, a reference memory task supposedly requiring fewer working memory resources. The experiment used two types of lists differing in familiarity. One was familiar to the pigeons through repeated exposure, whereas the other was novel in every new session. In test sessions, pigeons could choose between a trial with a hint specifying the next item to peck and one with no hint. However, successful responses in trials with a hint resulted in lowered rates of primary reinforcement: .60 in the first test and .75 in the second. Results showed that two of four pigeons chose the trial with a hint significantly more often before receiving a novel list than the familiar list in the four sessions of the first test, and three did so in the second test. Impressively, one bird showed robust evidence in the very first sessions in both tests. These results suggest that pigeons may monitor their long-term knowledge states and thereby control their environment before starting to solve a task.

  13. Can children take advantage of nao gaze-based hints during gameplay?

    NARCIS (Netherlands)

    Mwangi, E.N.; Diaz, M.; Barakova, E.I.; Catala, A.; Rauterberg, G.W.M.

    2017-01-01

    This paper presents a study that analyzes the effects of robots' gaze hints on children's performance in a card-matching game. We conducted a within-subjects study, in which children played a card matching game "Memory" in the presence of a robot tutor in two sessions. In one session, the robot gave

  14. Theory of mind in a first-episode psychosis population using the Hinting Task.

    Science.gov (United States)

    Lindgren, Maija; Torniainen-Holm, Minna; Heiskanen, Inkeri; Voutilainen, Greta; Pulkkinen, Ulla; Mehtälä, Tuukka; Jokela, Markus; Kieseppä, Tuula; Suvisaari, Jaana; Therman, Sebastian

    2018-05-01

    Deficiencies in theory of mind (ToM) are common in psychosis and may largely explain impaired social functioning. Currently, it is unclear whether impairments in ToM are explained by the more general cognitive deficits related to psychosis or whether ToM is impaired in psychosis independently of other cognitive deficits. This study examined ToM using the Hinting Task in young adults (n = 66) with first-episode psychosis and matched controls (n = 62). The participants were administered a broad neuropsychological assessment. Participants with psychosis performed worse than controls on the Hinting Task. However, 75% of the variance between the groups was explained by general cognitive deficits, especially impaired processing speed and episodic memory. Hinting Task performance of the best functioning patient group did not differ from that of the control group. When the psychosis group was divided according to diagnosis, the Hinting Task difference between individuals with schizophrenia and controls remained significant even when general cognitive performance was controlled for, suggesting specific verbal ToM deficits in schizophrenia. In contrast, those with other psychotic disorders did not differ from controls. Our results suggest that ToM deficits can be seen in early phases of psychotic disorders, schizophrenia in particular, and are partly independent of other cognitive functions. Copyright © 2018 Elsevier B.V. All rights reserved.

  15. Pedagogical Agent Gestures to Improve Learner Comprehension of Abstract Concepts in Hints

    Science.gov (United States)

    Martins, Igor; de Morais, Felipe; Schaab, Bruno; Jaques, Patricia

    2016-01-01

    In most Intelligent Tutoring Systems, the help messages (hints) are not very clear for students as they are only presented textually and have little connection with the task elements. This can lead to students' undesired behaviors, like gaming the system, associated with low performance. In this paper, the authors aim at evaluating if the gestures…

  16. Res Publicas käärib mäss / Hants Hint

    Index Scriptorium Estoniae

    Hint, Hants

    2002-01-01

    Res Publica eestseisuse liige ja Ida-Viru piirkonna esimees Hants Hint vastab küsimustele Res Publica ja Keskerakonna võimuliidu moodustamisega tekkinud skandaali, Res Publica esimehe Juhan Partsiga kohtumise kohta. Vt. samas: "Korbi toetajaid ootab hukkamõist"

  17. Data-Driven Hint Generation in Vast Solution Spaces: A Self-Improving Python Programming Tutor

    Science.gov (United States)

    Rivers, Kelly; Koedinger, Kenneth R.

    2017-01-01

    To provide personalized help to students who are working on code-writing problems, we introduce a data-driven tutoring system, ITAP (Intelligent Teaching Assistant for Programming). ITAP uses state abstraction, path construction, and state reification to automatically generate personalized hints for students, even when given states that have not…

  18. Stoic Behavior Hypothesis in Hint Seeking and Development of Reversi Learning Environment as Work Bench for Investigation

    Science.gov (United States)

    Miwa, Kazuhisa; Kojima, Kazuaki; Terai, Hitoshi

    2014-01-01

    Tutoring systems provide students with various types of on-demand and context-sensitive hints. Students are required to consciously adapt their help-seeking behavior, proactively seek help in some situations, and solve problems independently without supports in other situations. We define the latter behavior as stoic behavior in hint seeking. In…

  19. HINTS outperforms ABCD2 to screen for stroke in acute continuous vertigo and dizziness.

    Science.gov (United States)

    Newman-Toker, David E; Kerber, Kevin A; Hsieh, Yu-Hsiang; Pula, John H; Omron, Rodney; Saber Tehrani, Ali S; Mantokoudis, Georgios; Hanley, Daniel F; Zee, David S; Kattah, Jorge C

    2013-10-01

    Dizziness and vertigo account for about 4 million emergency department (ED) visits annually in the United States, and some 160,000 to 240,000 (4% to 6%) have cerebrovascular causes. Stroke diagnosis in ED patients with vertigo/dizziness is challenging because the majority have no obvious focal neurologic signs at initial presentation. The authors sought to compare the accuracy of two previously published approaches purported to be useful in bedside screening for possible stroke in dizziness: a clinical decision rule (head impulse, nystagmus type, test of skew [HINTS]) and a risk stratification rule (age, blood pressure, clinical features, duration of symptoms, diabetes [ABCD2]). This was a cross-sectional study of high-risk patients (more than one stroke risk factor) with acute vestibular syndrome (AVS; acute, persistent vertigo or dizziness with nystagmus, plus nausea or vomiting, head motion intolerance, and new gait unsteadiness) at a single academic center. All underwent neurootologic examination, neuroimaging (97.4% by magnetic resonance imaging [MRI]), and follow-up. ABCD2 risk scores (0-7 points), using the recommended cutoff of ≥4 for stroke, were compared to a three-component eye movement battery (HINTS). Sensitivity, specificity, and positive and negative likelihood ratios (LR+, LR-) were assessed for stroke and other central causes, and the results were stratified by age. False-negative initial neuroimaging was also assessed. A total of 190 adult AVS patients were assessed (1999-2012). Median age was 60.5 years (range = 18 to 92 years; interquartile range [IQR] = 52.0 to 70.0 years); 60.5% were men. Final diagnoses were vestibular neuritis (34.7%), posterior fossa stroke (59.5% [105 infarctions, eight hemorrhages]), and other central causes (5.8%). Median ABCD2 was 4.0 (range = 2 to 7; IQR = 3.0 to 4.0). ABCD2 ≥ 4 for stroke had sensitivity of 61.1%, specificity of 62.3%, LR+ of 1.62, and LR- of 0.62; sensitivity was lower for those

  20. Higgs hints

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1991-10-15

    As well as dominating the news at the recent Joint International Lepton-Photon Symposium and Europhysics Conference on High Energy Physics in Geneva, results from the four big experiments - Aleph , Delphi, L3 and Opal - at CERN's big LEP electron-positron collider had far-reaching implications.

  1. Employing UMLS for generating hints in a tutoring system for medical problem-based learning.

    Science.gov (United States)

    Kazi, Hameedullah; Haddawy, Peter; Suebnukarn, Siriwan

    2012-06-01

    While problem-based learning has become widely popular for imparting clinical reasoning skills, the dynamics of medical PBL require close attention to a small group of students, placing a burden on medical faculty, whose time is over taxed. Intelligent tutoring systems (ITSs) offer an attractive means to increase the amount of facilitated PBL training the students receive. But typical intelligent tutoring system architectures make use of a domain model that provides a limited set of approved solutions to problems presented to students. Student solutions that do not match the approved ones, but are otherwise partially correct, receive little acknowledgement as feedback, stifling broader reasoning. Allowing students to creatively explore the space of possible solutions is exactly one of the attractive features of PBL. This paper provides an alternative to the traditional ITS architecture by using a hint generation strategy that leverages a domain ontology to provide effective feedback. The concept hierarchy and co-occurrence between concepts in the domain ontology are drawn upon to ascertain partial correctness of a solution and guide student reasoning towards a correct solution. We describe the strategy incorporated in METEOR, a tutoring system for medical PBL, wherein the widely available UMLS is deployed and represented as the domain ontology. Evaluation of expert agreement with system generated hints on a 5-point likert scale resulted in an average score of 4.44 (Spearman's ρ=0.80, p<0.01). Hints containing partial correctness feedback scored significantly higher than those without it (Mann Whitney, p<0.001). Hints produced by a human expert received an average score of 4.2 (Spearman's ρ=0.80, p<0.01). Copyright © 2012 Elsevier Inc. All rights reserved.

  2. The Diagnostic Accuracy of Truncal Ataxia and HINTS as Cardinal Signs for Acute Vestibular Syndrome

    Directory of Open Access Journals (Sweden)

    Sergio Carmona

    2016-08-01

    Full Text Available The head impulse, nystagmus type, test of skew (HINTS protocol set a new paradigm to differentiate peripheral vestibular disease from stroke in patients with acute vestibular syndrome (AVS. The relationship between degree of truncal ataxia and stroke has not been systematically studied in patients with AVS. We studied a group of 114 patients who were admitted to a General Hospital due to AVS, 72 of them with vestibular neuritis (based on positive head impulse, abnormal caloric tests and negative MRI, and the rest with Stroke: 32 in the PICA territory (positive HINTS findings, positive MRI and 10 in the AICA territory (variable findings and grade 3 Ataxia, positive MRI. Truncal ataxia was measured by independent observers as grade 1, mild to moderate imbalance with walking independently; grade 2, severe imbalance with standing, but cannot walk without support; and grade 3, falling at upright posture.When we applied the HINTS protocol to our sample, we obtained 100% sensitivity and 94.4% specificity, similar to previously published findings. Only those patients with stroke presented with grade 3 ataxia. Of those with grade 2 ataxia (n = 38, 11 had cerebellar stroke and 28 had vestibular neuritis, not related to the patient's age. Grade 2-3 ataxia was 92.9% sensitive and 61.1% specific to detect AICA/PICA stroke in patients with AVS, with 100% sensitivity to detect AICA stroke. In turn, two signs (nystagmus of central origin and grade 2-3 Ataxia had 100% sensitivity and 61.1% specificity. Ataxia is less sensitive than HINTS but much easier to evaluate.

  3. Anti-depressant and anxiolytic like behaviors in PKCI/HINT1 knockout mice associated with elevated plasma corticosterone level

    Directory of Open Access Journals (Sweden)

    Wang Jia

    2009-11-01

    Full Text Available Abstract Background Protein kinase C interacting protein (PKCI/HINT1 is a small protein belonging to the histidine triad (HIT family proteins. Its brain immunoreactivity is located in neurons and neuronal processes. PKCI/HINT1 gene knockout (KO mice display hyper-locomotion in response to D-amphetamine which is considered a positive symptom of schizophrenia in animal models. Postmortem studies identified PKCI/HINT1 as a candidate molecule for schizophrenia and bipolar disorder. We investigated the hypothesis that the PKCI/HINT1 gene may play an important role in regulating mood function in the CNS. We submitted PKCI/HINT1 KO mice and their wild type (WT littermates to behavioral tests used to study anti-depressant, anxiety like behaviors, and goal-oriented behavior. Additionally, as many mood disorders coincide with modifications of hypothalamic-pituitary-adrenal (HPA axis function, we assessed the HPA activity through measurement of plasma corticosterone levels. Results Compared to the WT controls, KO mice exhibited less immobility in the forced swim (FST and the tail suspension (TST tests. Activity in the TST tended to be attenuated by acute treatment with valproate at 300 mg/kg in KO mice. The PKCI/HINT1 KO mice presented less thigmotaxis in the Morris water maze and spent progressively more time in the lit compartment in the light/dark test. In a place navigation task, KO mice exhibited enhanced acquisition and retention. Furthermore, the afternoon basal plasma corticosterone level in PKCI/HINT1 KO mice was significantly higher than in the WT. Conclusion PKCI/HINT1 KO mice displayed a phenotype of behavioral and endocrine features which indicate changes of mood function, including anxiolytic-like and anti-depressant like behaviors, in conjunction with an elevated corticosterone level in plasma. These results suggest that the PKCI/HINT 1 gene could be important for the mood regulation function in the CNS.

  4. Mööbel suvekodusse / Aili Ermel

    Index Scriptorium Estoniae

    Ermel, Aili

    2008-01-01

    2008. a. Milano messil "Salone Internazionale del Mobile" oli mööblit, mis projekteeritud ekstra õuele, aga oli ka sellist, mis sobib suvel õue ja talvel tuppa. Mööbel firmalt Cappellini, Gervason (disainer Paola Navone), Horm (disainer Mario Bellini), Zanotta (disainerid Gae Aulenti, Prospero Rasulo, Emaf Progetti, Roberto Barbieri), EMU (disainer Patricia Urquiola), Moroso (disainerid Nipa Doshi, Jonhatan Levien, Edward Van Vliet), Cassina (Tokujin Yoshioka) ja RODA. 14 värv. ill

  5. Axion-like particles: possible hints and constraints from the high-energy Universe

    International Nuclear Information System (INIS)

    Brun, Pierre

    2013-01-01

    The high-energy Universe is potentially a great laboratory for searching new light bosons such as axion-like particles (ALPs). Cosmic sources are indeed the scene of violent phenomena that involve strong magnetic field and/or very long baselines, where the effects of the mixing of photons with ALPs could lead to observable effects. Two examples are archetypal of this fact, that are the Universe opacity to gamma-rays and the imprints of astrophysical magnetic turbulence in the energy spectra of high-energy sources. In the first case, hints for the existence of ALPs can be proposed whereas the second one is used to put constraints on the ALP mass and coupling to photons

  6. Hint of nonstandard Mikheyev-Smirnov-Wolfenstein dynamics in solar neutrino conversion

    International Nuclear Information System (INIS)

    Palazzo, Antonio

    2011-01-01

    Motivated by the recent low-threshold measurements of the solar 8 B neutrino spectrum performed by Borexino, Super-Kamiokande and the Sudbury Neutrino Observatory--all now monitoring the transition regime between low-energy (vacuumlike) and high-energy (matter-dominated) flavor conversions--we consider the role of subdominant dynamical terms induced by new flavor-changing interactions. We find that the presence of such perturbations with strength ∼10 -1 G F is now favored, offering a better description of the anomalous behavior suggested by the new results, whose spectrum shows no sign of the typical low-energy upturn predicted by the standard Mikheyev-Smirnov-Wolfenstein (MSW) mechanism. Our findings, if interpreted in a 2-flavor scheme, provide a hint of such new interactions at the ∼2σ level, which is rather robust with respect to 3-flavor effects possibly induced by nonzero θ 13 .

  7. Hint of nonstandard Mikheyev-Smirnov-Wolfenstein dynamics in solar neutrino conversion

    Science.gov (United States)

    Palazzo, Antonio

    2011-05-01

    Motivated by the recent low-threshold measurements of the solar B8 neutrino spectrum performed by Borexino, Super-Kamiokande and the Sudbury Neutrino Observatory—all now monitoring the transition regime between low-energy (vacuumlike) and high-energy (matter-dominated) flavor conversions—we consider the role of subdominant dynamical terms induced by new flavor-changing interactions. We find that the presence of such perturbations with strength ˜10-1GF is now favored, offering a better description of the anomalous behavior suggested by the new results, whose spectrum shows no sign of the typical low-energy upturn predicted by the standard Mikheyev-Smirnov-Wolfenstein (MSW) mechanism. Our findings, if interpreted in a 2-flavor scheme, provide a hint of such new interactions at the ˜2σ level, which is rather robust with respect to 3-flavor effects possibly induced by nonzero θ13.

  8. Hints for clarification of influencing factors in case of occupational liver diseases

    Energy Technology Data Exchange (ETDEWEB)

    Zober, A; Raithel, H; Valentin, H

    1981-05-01

    Clarification of influencing factors is of great importance in suspected occupational liver diseases. Hints are given on the basis of the author's own experience and after critical evaluation of the relevant literature. Most important are: 1) Establishment of a comprehensive working anamnesis with special regard to specific features of the job, exposure patterns, and all working materials; 2) assessment of the hepatotoxic potential of the suspected working material according to the present state of knowledge in working medicine and toxicology; 3) objectification and quantification of the suspected noxious substances at the place of work by means of air analysis and analysis of the biological matter; 4) differential diagnosis in view of possible competitive influencing factors.

  9. Hint of a Z' boson from the CERN LEP II data

    International Nuclear Information System (INIS)

    Gulov, A. V.; Skalozub, V. V.

    2007-01-01

    The many-parametric fits of the LEP2 data on e + e - →e + e - , μ + μ - , τ + τ - processes are performed with the goal to estimate the signals of the Abelian Z ' boson. Four independent parameters must be fitted, if the derived already low-energy relations between the Z ' couplings to the standard model fermions are taken into consideration. No signals are found when the complete LEP2 data set for these processes is treated. In the fit of the backward bins, the hint at the 1.3σ confidence level is detected. The Z ' couplings to the vector and axial-vector lepton currents are constrained. The comparisons with the one-parameter fits and with the corresponding LEP1 experiments are fulfilled

  10. Modelling magnetic islands in the H-1NF heliac with the hint code

    International Nuclear Information System (INIS)

    Lloyd, S.S.; Gardner, H.J.

    1999-01-01

    Full text: Recent progress in the theoretical modelling of the effects of plasma pressure on the growth and change in geometry of magnetic islands in the H-1NF Heliac will be reviewed. The HINT magnetohydrodynamic equilibrium code, which has become a standard workhorse in the stellarator community for problems of this type, has been modified to incorporate an interpolation algorithm which significantly accelerates its convergence. This has enabled the critical evaluation of earlier results, and of some conventional wisdom. In many ways the treatment of magnetic islands in low shear fusion reactors, such as H-1NF, is an ideal case study in computational science - the devil is in the details and the devil is important: the existence or otherwise of island self-healing at reactor pressures could significantly affect the design of future experiments. (author)

  11. Altered Light Conditions Contribute to Abnormalities in Emotion and Cognition Through HINT1 Dysfunction in C57BL/6 Mice

    Directory of Open Access Journals (Sweden)

    Yuan Zhou

    2018-06-01

    Full Text Available In recent years, the environmental impact of artificial light at night has been a rapidly growing global problem, affecting 99% of the population in the US and Europe, and 62% of the world population. The present study utilized a mouse model exposed to long-term artificial light and light deprivation to explore the impact of these conditions on emotion and cognition. Based on the potential links between histidine triad nucleotide binding protein 1 (HINT1 and mood disorders, we also examined the expression of HINT1 and related apoptosis factors in the suprachiasmatic nucleus (SCN, prefrontal cortex (PFC, nucleus accumbens (NAc and hippocampus (Hip. Mice exposed to constant light (CL exhibited depressive- and anxiety-like behaviors, as well as impaired spatial memory, as demonstrated by an increased immobility time in the tail suspension and forced swimming tests, less entries and time spent in the open arms of elevated plus-maze, and less platform site crossings and time spent in the target quadrant in the Morris water maze (MWM. The effects of constant darkness (CD partially coincided with long-term illumination, except that mice in the CD group failed to show anxiety-like behaviors. Furthermore, HINT1 was upregulated in four encephalic regions, indicating that HINT1 may be involved in mood disorders and cognitive impairments due to altered light exposure. The apoptosis-related proteins, BAX and BCL-2, showed the opposite expression pattern, reflecting an activated apoptotic pathway. These findings suggest that exposure to CL and/or darkness can induce significant changes in affective and cognitive responses, possibly through HINT1-induced activation of apoptotic pathways.

  12. Seven Hints for Primordial Black Hole Dark Matter arXiv

    CERN Document Server

    Clesse, Sebastien

    Seven observations point towards the existence of primordial black holes (PBH), constituting the whole or an important fraction of the dark matter in the Universe: the mass and spin of black holes detected by Advanced LIGO/VIRGO, the detection of micro-lensing events of distant quasars and stars in M31, the non-detection of ultra-faint dwarf satellite galaxies with radius below 15 parsecs, evidences for core galactic dark matter profiles, the correlation between X-ray and infrared cosmic backgrounds, and the existence of super-massive black holes very early in the Universe's history. Some of these hints are newly identified and they are all intriguingly compatible with the re-constructed broad PBH mass distribution from LIGO events, peaking on PBH mass $m_{\\rm PBH} \\approx 3 M_\\odot$ and passing all other constraints on PBH abundances. PBH dark matter also provides a new mechanism to explain the mass-to-light ratios of dwarf galaxies, including the recent detection of a diffuse galaxy not dominated by dark ma...

  13. HEALTH INFO SANTÉ – REMINDER ANNUAL DEDUCTIBLE AND REIMBURSEMENT CLAIMS HINTS FOR USE

    CERN Multimedia

    CHIS Board

    2000-01-01

    Information from the CHIS Board and the Human Resources Division:Annual deductible and reimbursement claims: hints for useOne should bear in mind that the annual deductible is an amount (currently CHF 100) charged automatically by the Administrator of the scheme for every adult aged 18 and above. This is what happens: The amount is deducted annually for all medical services received over a calendar year.It is triggered by the date of the treatment and neither by the date of the bill nor that of the reimbursement claim.In other words, if you receive medical treatment in December for the first time in a given year, the CHF 100 will be deducted from the claim for that treatment. So, except for urgent cases, it would be better to wait till the following month, thus avoiding one annual deductible.It is also worth remembering that the cost of processing our reimbursement claims - and there were 54, 000 in 1999 - is part of the cost of our insurance.Help keep administrative costs down: do not submit reimbursement cl...

  14. Development and Validation of a Novel Generic Health-related Quality of Life Instrument With 20 Items (HINT-20

    Directory of Open Access Journals (Sweden)

    Min-Woo Jo

    2017-01-01

    Full Text Available Objectives Few attempts have been made to develop a generic health-related quality of life (HRQoL instrument and to examine its validity and reliability in Korea. We aimed to do this in our present study. Methods After a literature review of existing generic HRQoL instruments, a focus group discussion, in-depth interviews, and expert consultations, we selected 30 tentative items for a new HRQoL measure. These items were evaluated by assessing their ceiling effects, difficulty, and redundancy in the first survey. To validate the HRQoL instrument that was developed, known-groups validity and convergent/discriminant validity were evaluated and its test-retest reliability was examined in the second survey. Results Of the 30 items originally assessed for the HRQoL instrument, four were excluded due to high ceiling effects and six were removed due to redundancy. We ultimately developed a HRQoL instrument with a reduced number of 20 items, known as the Health-related Quality of Life Instrument with 20 items (HINT-20, incorporating physical, mental, social, and positive health dimensions. The results of the HINT-20 for known-groups validity were poorer in women, the elderly, and those with a low income. For convergent/discriminant validity, the correlation coefficients of items (except vitality in the physical health dimension with the physical component summary of the Short Form 36 version 2 (SF-36v2 were generally higher than the correlations of those items with the mental component summary of the SF-36v2, and vice versa. Regarding test-retest reliability, the intraclass correlation coefficient of the total HINT-20 score was 0.813 (p<0.001. Conclusions A novel generic HRQoL instrument, the HINT-20, was developed for the Korean general population and showed acceptable validity and reliability.

  15. Hint from the interfamily mass hierarchy: Two vectorlike families in the TeV range

    Science.gov (United States)

    Babu, K. S.; Pati, Jogesh C.; Stremnitzer, Hanns

    1995-03-01

    Two vectorlike familes QL,R=(U, D, N, E)L,R and Q'L,R=(U', D', N', E')L,R with masses of order 1 TeV, one of which is a doublet of SU(2)L and the other a doublet of SU(2)R, have been predicted to exist, together with the three observed chiral families, in the context of a viable and economical SUSY preon model. The model itself possesses many attractive features which include explanations of the origins of (i) diverse mass scales, (ii) family replication, (iii) protection of the masses of the composite quarks and leptons compared to their compositeness scales, and (iv) interfamily mass hierarchy. The existence of the two vectorlike familes, a prediction of the model, turns out to be crucial especially for an explanation of the interfamily mass hierarchy (IFMH). Given the simplicity of the explanation, the observed IFMH in turn appears to us to be a strong hint in favor of the existence of the two vectorlike families. This paper is devoted to a detailed study of the expected masses, mixings and decay modes of the fermions belonging to the two vectorlike families, in the context of the SUSY preon model, with the inclusion of the renormalization effects due to the standard model gauge interactions. Including QCQ renormalization effects, the masses of the vectorlike quarks are expected to lie in the range of 500 GeV to about 2.5 TeV, while those of the vectorlike leptons are expected to be in the range of 200 GeV to 1 TeV. Their mass pattern and decay modes exhibit certain distinguishing features and characteristic signals. For example, when the CERN LHC and, possibly a future version of the SSC are built, pair production of the vectorlike quarks would lead to systems such as (bb¯+4Z+W+W-) and (bb¯+2Z+W+W-), while an e-e+ linear collider (NLC) of suitable energy can produce appreciably a single neutral heavy lepton N together, with ντ, followed by the decay of N into (Z+ντ)-->(e-e+)+ντ. This last signal may conceivably materialize even at CERN LEP 200 if N is

  16. Smartphone Ownership Among US Adult Cigarette Smokers: 2014 Health Information National Trends Survey (HINTS) Data.

    Science.gov (United States)

    Heffner, Jaimee L; Mull, Kristin E

    2017-08-31

    Despite increasing interest in smartphone apps as a platform for delivery of tobacco cessation interventions, no previous studies have evaluated the prevalence and characteristics of smokers who can access smartphone-delivered interventions. To guide treatment development in this new platform and to evaluate disparities in access to smartphone-delivered interventions, we examined associations of smartphone ownership with demographics, tobacco use and thoughts about quitting, other health behaviors, physical and mental health, health care access, and Internet and technology utilization using a nationally representative sample of US adult smokers. Data were from the National Cancer Institute's 2014 Health Information National Trends Survey 4 (HINTS 4), Cycle 4. This mailed survey targeted noninstitutionalized individuals aged 18 years or older using two-stage stratified random sampling. For this analysis, we restricted the sample to current smokers with complete data on smartphone ownership (n=479). Nearly two-thirds (weighted percent=63.8%, 248/479) of smokers reported owning a smartphone. Those who were younger (P<.001), employed (P=.002), never married (P=.002), and had higher education (P=.002) and income (P<.001) had the highest rates of ownership. Smartphone owners did not differ from nonowners on frequency of smoking, recent quit attempts, or future plans to quit smoking, although they reported greater belief in the benefits of quitting (P=.04). Despite being equally likely to be overweight or obese, smartphone owners reported greater fruit and vegetable consumption (P=.03) and were more likely to report past-year efforts to increase exercise (P=.001) and to lose weight (P=.02). No differences in health care access and utilization were found. Smartphone owners reported better physical and mental health in several domains and higher access to and utilization of technology and the Internet, including for health reasons. Smartphone ownership among smokers mirrors

  17. PsHint1, associated with the G-protein α subunit PsGPA1, is required for the chemotaxis and pathogenicity of Phytophthora sojae.

    Science.gov (United States)

    Zhang, Xin; Zhai, Chunhua; Hua, Chenlei; Qiu, Min; Hao, Yujuan; Nie, Pingping; Ye, Wenwu; Wang, Yuanchao

    2016-02-01

    Zoospore chemotaxis to soybean isoflavones is essential in the early stages of infection by the oomycete pathogen Phytophthora sojae. Previously, we have identified a G-protein α subunit encoded by PsGPA1 which regulates the chemotaxis and pathogenicity of P. sojae. In the present study, we used affinity purification to identify PsGPA1-interacting proteins, including PsHint1, a histidine triad (HIT) domain-containing protein orthologous to human HIT nucleotide-binding protein 1 (HINT1). PsHint1 interacted with both the guanosine triphosphate (GTP)- and guanosine diphosphate (GDP)-bound forms of PsGPA1. An analysis of the gene-silenced transformants revealed that PsHint1 was involved in the chemotropic response of zoospores to the isoflavone daidzein. During interaction with a susceptible soybean cultivar, PsHint1-silenced transformants displayed significantly reduced infectious hyphal extension and caused a strong cell death in plants. In addition, the transformants displayed defective cyst germination, forming abnormal germ tubes that were highly branched and exhibited apical swelling. These results suggest that PsHint1 not only regulates chemotaxis by interacting with PsGPA1, but also participates in a Gα-independent pathway involved in the pathogenicity of P. sojae. © 2015 BSPP AND JOHN WILEY & SONS LTD.

  18. Health Information National Trends Survey in American Sign Language (HINTS-ASL): Protocol for the Cultural Adaptation and Linguistic Validation of a National Survey.

    Science.gov (United States)

    Kushalnagar, Poorna; Harris, Raychelle; Paludneviciene, Raylene; Hoglind, TraciAnn

    2017-09-13

    The Health Information National Trends Survey (HINTS) collects nationally representative data about the American's public use of health-related information. This survey is available in English and Spanish, but not in American Sign Language (ASL). Thus, the exclusion of ASL users from these national health information survey studies has led to a significant gap in knowledge of Internet usage for health information access in this underserved and understudied population. The objectives of this study are (1) to culturally adapt and linguistically translate the HINTS items to ASL (HINTS-ASL); and (2) to gather information about deaf people's health information seeking behaviors across technology-mediated platforms. We modified the standard procedures developed at the US National Center for Health Statistics Cognitive Survey Laboratory to culturally adapt and translate HINTS items to ASL. Cognitive interviews were conducted to assess clarity and delivery of these HINTS-ASL items. Final ASL video items were uploaded to a protected online survey website. The HINTS-ASL online survey has been administered to over 1350 deaf adults (ages 18 to 90 and up) who use ASL. Data collection is ongoing and includes deaf adult signers across the United States. Some items from HINTS item bank required cultural adaptation for use with deaf people who use accessible services or technology. A separate item bank for deaf-related experiences was created, reflecting deaf-specific technology such as sharing health-related ASL videos through social network sites and using video remote interpreting services in health settings. After data collection is complete, we will conduct a series of analyses on deaf people's health information seeking behaviors across technology-mediated platforms. HINTS-ASL is an accessible health information national trends survey, which includes a culturally appropriate set of items that are relevant to the experiences of deaf people who use ASL. The final HINTS

  19. ALGUNAS PAUTAS PARA LA ESCRITURA DE ARTÍCULOS CIENTÍFICOS SOME HINTS FOR WRITING SCIENTIFIC PAPERS

    Directory of Open Access Journals (Sweden)

    Carlos M Zapata

    2008-06-01

    Full Text Available El objetivo de este artículo es presentar, a aquellos investigadores neófitos, una serie de pautas que faciliten los procesos de escritura y publicación de manuscritos en revistas científicas de corriente principal. En la comunidad científica, una investigación sólo se completa cuando los resultados se socializan a través de artículos en revistas arbitradas que garanticen la originalidad, importancia y validez científica de los hallazgos reportados. Consecuentemente, es necesario que los investigadores desarrollen destrezas y habilidades en la escritura científica. Sin embargo, el proceso de preparación de un manuscrito, desde su fase inicial hasta su publicación final, suele ser largo y difícil, debido a algunos factores clave que tienen influencia sobre su calidad. Este artículo, suministra lineamientos generales sobre la preparación de manuscritos y entrega, también, pautas alrededor de las buenas prácticas de escritura de artículos con miras a facilitar la revisión por parte de los árbitros. En este sentido, este trabajo constituye aporte para quienes se inician en la difusión de la investigación científica.The objective of this paper is to present, to those neophyte researchers, a set of hints that facilitate manuscript writing and publishing processes needed for high class scientific journals. In the scientific community, a research would only be completed when the results are shared through papers in peer-reviewed journals that guarantees the originality, importance and scientific validation of reported contributions. Consequently, researchers have the necessity to develop skills and abilities in scientific writing. However, the manuscript preparation process from the initial phase to the final publication is usually slow and difficult, due to some key factors having influence over its quality. In this paper, we present general guidelines about manuscript preparation and we give some hints about good scientific

  20. W7-X vacuum and finite-β magnetic field structure resolved with the HINT 3D equilibrium code

    International Nuclear Information System (INIS)

    Hayashi, T.; Merkel, P.; Nuehrenberg, J.; Schwenn, U.

    1994-01-01

    The 3D equilibrium code HINT allows the direct investigation of finite-β effects on sizes and phases of islands in genuinely 3D configurations like the W7-X stellarator planned by the Max-Planck-Institut fuer Plasmaphysik in Germany. The code does not require the existence of nested flux surfaces. This, in contrast to the inverse formulation used in the VMEC code, leads to a considerably more complex computational goal. The HINT code combines some crucial features reducing the numerical problems and the computational effort to such an extent as to allow computation of 3D equilibria at finite-β with magnetic islands. The code is based on a two-step procedure: Starting from a given B and an initial pressure, the iteration technique for the pressure advancement is differencing in an artificial time with an explicit 4th order scheme, or - alternatively for resolving the island topology - field lines starting from all gridpoints are followed long enough to allow pressure equalization along these. B.∇p 0, for fixed B. In a second step, p is kept fixed and B is advanced with an artificial time for solving ∇p - jxB = 0 under the constraint of vanishing toroidal current J. The differential equations are discretized in space with 4th order difference approximations on an Eulerian grid spanned by a rectangular box whose toroidal rotation law follows the W7-X geometry. The two sub-iteration steps are repeated until the force balance is satisfied to an appropriate accuracy. The boundaries (where the boundary conditions are prescribed) are far enough away from the last closed magnetic surface, thus guaranteeing the motion of the plasma column not being constrained by the boundary conditions. Due to the stellarator symmetry in the toroidal direction only half of an equilibrium period is computed, using modified periodic boundary conditions guaranteeing the 4th order of the spatial discretization. (author) 5 refs., 4 figs

  1. Asjadeküllane Decorate Life / Aili Ermel

    Index Scriptorium Estoniae

    Ermel, Aili

    2008-01-01

    Frankfurdis juulis toimunud tarbekaupade messist "Decorate Life". Noorte disainerite Kotaro Nishibori ja Sebastian Herkneri valgustid ning René Mülleri täispuidust tooted (firma Woodloops) tuppa ja terrassile

  2. Kultuuritrauma ja elulood : Lectio praecursoria / Aili Aarelaid-Tart

    Index Scriptorium Estoniae

    Aarelaid-Tart, Aili, 1947-2014

    2007-01-01

    Avalikku akadeemilist väitlust sissejuhatav tekst, mis on esitatud Helsingi Ülikooli sotsiaalteaduskonna sotsiaalpoliitika osakonnas 9. XI 2006 sotsiaalteaduste doktorikraadi kaitsmisel. Uurimus on publitseeritud raamatuna "Cultural Trauma and Life Stories" Helsinki : Kikimora Publications, 2006

  3. Naised põllumajanduses = Women in agriculture / Aili Maanso

    Index Scriptorium Estoniae

    Maanso, Aili

    2006-01-01

    2005. a. struktuuriuuringu andmetel oli Eesti ligi 28 000 põllumajanduslikus majapidamises 90 850 hõivatut. Püsitööjõust (peretööjõud ja alalised töötajad) oli mehi 51,1% ja naisi 48,9%, 37% majapidamistest oli naisjuht. Majapidamiste juhid soo ja vanuse järgi. Tabelid

  4. Domineerib kindlustus surmajuhtumiks / Aili Kukumägi

    Index Scriptorium Estoniae

    Kukumägi, Aili

    1996-01-01

    Lisatud tabelid, milles elukindlustusseltside preemiad, elukindlustusseltside väljamakstud nõuded, 1995.aasta elukindlustuseraldised. Joonised elu- ja kahjukindlustuse osatähtsuse kohta 1994. ja 1995.aastal

  5. Patient-provider discussion of online health information: results from the 2007 Health Information National Trends Survey (HINTS).

    Science.gov (United States)

    Chung, Jae Eun

    2013-01-01

    Increasing numbers of people have turned to the Internet for health information. Little has been done beyond speculation to empirically investigate patients' discussion of online health information with health care professionals (HCPs) and patients' perception of HCPs' reactions to such discussion. The author analyzed data from the 2007 Health Information National Trends Survey (HINTS) to identify the characteristics of patients (a) who search for health information on the Internet, (b) who discuss the information found on the Internet with HCPs, and (c) who positively assess HCPs' reaction to the online information. Findings show that men were more likely than were women to have a conversation on online information with HCPs. It is unfortunate that patients who had trouble understanding or trusting online health information were no more likely to ask questions to or seek guidance from HCPs. Reactions of HCPs to online information were perceived as particularly negative by certain groups of patients, such as those who experienced poor health and those who had more concerns about the quality of their searched information. Results are discussed for their implications for patient empowerment and patient-HCP relationships.

  6. Hints for Diagnosis

    DEFF Research Database (Denmark)

    Poulsen, Lars K

    2015-01-01

    /or caretakers. Based on this, a provisional decision to pursue a food allergy diagnosis may be made after carefully considering other possible reasons for an adverse reaction to a food: aversion, infection, intoxication, or an underlying metabolic disease. To respond to the next question, the anamnesis...

  7. Perturbed Lepton-Specific Two-Higgs-Doublet Model Facing Experimental Hints for Physics beyond the Standard Model.

    Science.gov (United States)

    Crivellin, Andreas; Heeck, Julian; Stoffer, Peter

    2016-02-26

    BABAR, Belle, and LHCb Collaborations report evidence for new physics in B→Dτν and B→D^{*}τν of approximately 3.8σ. There is also the long lasting discrepancy of about 3σ in the anomalous magnetic moment of the muon, and the branching ratio for τ→μνν is 1.8σ (2.4σ) above the standard model expectation using the HFAG (PDG) values. Furthermore, CMS Collaboration finds hints for a nonzero decay rate of h→μτ. Interestingly, all these observations can be explained by introducing new scalars. In this Letter we consider these processes within a lepton-specific two-Higgs doublet model (i.e., of type X) with additional nonstandard Yukawa couplings. It is found that one can accommodate τ→μνν with modified Higgs-τ couplings. The anomalous magnetic moment of the muon can be explained if the additional neutral CP-even Higgs boson H is light (below 100 GeV). Also R(D) and R(D^{*}) can be easily explained by additional t-c-Higgs couplings. Combining these t-c couplings with a light H the decay rate for t→Hc can be in a testable range for the LHC. Effects in h→μτ are also possible, but in this case a simultaneous explanation of the anomalous magnetic moment of the muon is difficult due to the unavoidable τ→μγ decay.

  8. Kihelkonnamäng elust ja armastusest algab homme / Regina Lilleorg

    Index Scriptorium Estoniae

    Lilleorg, Regina

    2008-01-01

    Kuusalu kihelkonnamängust "Õhtune jalutuskäik Laane Leeni ja Oru Antoniga", mis käsitleb kirjanik Anton Hansen Tammsaare noorusaega Kuusalu mail Koitjärve lähistel. Kihelkonnamängu korraldab Kuusalu vallas tegutsev MTÜ Veljo Tormise Kultuuriselts (kihelkonnamänge korraldatakse 2000. aastast alates). N'äidendite autor on Saima Kallionsivu. Osalevad Kuusalu keskkooli näitering, õpetajad, kohalikud inimesed ja ka tallinlased

  9. Heliseva Ungari tõid Harjumaa ballile Mariza, Silva ja krahv Luxemburg / Regina Lilleorg

    Index Scriptorium Estoniae

    Lilleorg, Regina

    2005-01-01

    Traditsioonilisest Harjumaa ballist 30. dets. Rahvusooperis Estonia, kontserdist "Helisev Ungari", jazzikavast "Night and Day", noorte harjumaalaste esinemisest Talveaias. Estonia Valges saalis anti maavanema vastuvõtul teiste seas teenetemärk Harry Illakule Harjumaa Noorte Puhkpilliorkestri loomise ja puhkpillimuusika edendamise eest ja teenetemärk ning Harjumaa Kultuuripärli preemia kultuuritöötajale Aime Bahovskile. Harju Maavalitsuse, Harjumaa Omavalitsuste Liidu ja Rahvusooper Estonia kolmepoolsest koostöölepingust

  10. Estonian Airi ümber käib lehmakauplemine / Tõnu Lilleorg

    Index Scriptorium Estoniae

    Lilleorg, Tõnu

    2008-01-01

    Skandinaavia lennukompanii SAS saatis Eesti valitsusele kirja, milles teatab, et on nõus raskustes Estonian Airile lisainvesteeringuid tegema vaid siis, kui riik müüb SAS-ile oma osaluse, 34%. Vt. samas: SAS ei taha lennufirma eest maksta üle 150 miljoni. Diagramm: Majandusnäitajad, omanikud

  11. Läbi tantsu kasvame suureks pereks / Steven Toomela, Gert Erik ; interv. Regina Lilleorg

    Index Scriptorium Estoniae

    Toomela, Steven

    2006-01-01

    Vabariikliku noorte tantsijate X suvelaagri lõputööna etendub vabaõhumuusikal "Kaua võib" (stsenarist Rünno Karna, muusika autor ja projektijuht Kalle Erm, kunstnik Rait Potisepp, dirigent Hirvo Surva). Püünsi põhikooli tantsulapsed sellest, mis laagris meeltmööda ja mis mitte. Vastab ka laste õpetaja Hele Pomerants

  12. President Ilves sattus YouTube'i tarkust jagama / Tõnu Lilleorg

    Index Scriptorium Estoniae

    Lilleorg, Tõnu

    2008-01-01

    President Toomas Hendrik Ilvese majandusteemalisest videoläkitusest portaalis YouTube. Arvamust avaldavad Balti meedia- ja filmikooli õppedirektor Hagi Šein, Riigikogu liige Vilja Savisaar ja kommunikatsioonikonsultant Raul Rebane. Vt. ka juhtkiri lk. 12: Kes tegi? Ilves ise tegi! Õhtulehe arvates vastutab majanduskriisi eest ka president ise. Lisatud karikatuur. Juhtkiri ilmunud ka: Molodjož Estonii 11. dets. 2008, lk. 4, pealk.: Kto vinovat?

  13. The human interactome knowledge base (hint-kb): An integrative human protein interaction database enriched with predicted protein–protein interaction scores using a novel hybrid technique

    KAUST Repository

    Theofilatos, Konstantinos A.

    2013-07-12

    Proteins are the functional components of many cellular processes and the identification of their physical protein–protein interactions (PPIs) is an area of mature academic research. Various databases have been developed containing information about experimentally and computationally detected human PPIs as well as their corresponding annotation data. However, these databases contain many false positive interactions, are partial and only a few of them incorporate data from various sources. To overcome these limitations, we have developed HINT-KB (http://biotools.ceid.upatras.gr/hint-kb/), a knowledge base that integrates data from various sources, provides a user-friendly interface for their retrieval, cal-culatesasetoffeaturesofinterest and computesaconfidence score for every candidate protein interaction. This confidence score is essential for filtering the false positive interactions which are present in existing databases, predicting new protein interactions and measuring the frequency of each true protein interaction. For this reason, a novel machine learning hybrid methodology, called (Evolutionary Kalman Mathematical Modelling—EvoKalMaModel), was used to achieve an accurate and interpretable scoring methodology. The experimental results indicated that the proposed scoring scheme outperforms existing computational methods for the prediction of PPIs.

  14. The relationship between high-frequency pure-tone hearing loss, hearing in noise test (HINT) thresholds, and the articulation index.

    Science.gov (United States)

    Vermiglio, Andrew J; Soli, Sigfrid D; Freed, Daniel J; Fisher, Laurel M

    2012-01-01

    Speech recognition in noise testing has been conducted at least since the 1940s (Dickson et al, 1946). The ability to recognize speech in noise is a distinct function of the auditory system (Plomp, 1978). According to Kochkin (2002), difficulty recognizing speech in noise is the primary complaint of hearing aid users. However, speech recognition in noise testing has not found widespread use in the field of audiology (Mueller, 2003; Strom, 2003; Tannenbaum and Rosenfeld, 1996). The audiogram has been used as the "gold standard" for hearing ability. However, the audiogram is a poor indicator of speech recognition in noise ability. This study investigates the relationship between pure-tone thresholds, the articulation index, and the ability to recognize speech in quiet and in noise. Pure-tone thresholds were measured for audiometric frequencies 250-6000 Hz. Pure-tone threshold groups were created. These included a normal threshold group and slight, mild, severe, and profound high-frequency pure-tone threshold groups. Speech recognition thresholds in quiet and in noise were obtained using the Hearing in Noise Test (HINT) (Nilsson et al, 1994; Vermiglio, 2008). The articulation index was determined by using Pavlovic's method with pure-tone thresholds (Pavlovic, 1989, 1991). Two hundred seventy-eight participants were tested. All participants were native speakers of American English. Sixty-three of the original participants were removed in order to create groups of participants with normal low-frequency pure-tone thresholds and relatively symmetrical high-frequency pure-tone threshold groups. The final set of 215 participants had a mean age of 33 yr with a range of 17-59 yr. Pure-tone threshold data were collected using the Hughson-Weslake procedure. Speech recognition data were collected using a Windows-based HINT software system. Statistical analyses were conducted using descriptive, correlational, and multivariate analysis of covariance (MANCOVA) statistics. The

  15. Hints on cost- and energy saving during lime-sand brick production; Hinweise zur Kosten- und Energieeinsparung bei der Kalksandstein-Produktion

    Energy Technology Data Exchange (ETDEWEB)

    Eden, W.

    2001-05-01

    The publication contains hints for reduction of energy consumption and cost in lime-sand brick production. The information was compiled by Bundesverband Kalksandsteinindustrie e.V. and was derived from technical discussions of the master seminars on production technology of the years 1995 - 2000, consultations form member organizations, or from other sources. [German] Diese Arbeit ist eine Zusammenstellung von Hinweisen zur Reduzierung des Energieverbrauchs und der Kostensenkung bei der KS-Produktion und soll eine Hilfestellung bei entsprechenden Rationalisierungsmassnahmen in den Mitgliedsunternehmen sein. Die hier aufgefuehrten Hinweise und Anregungen entstammen den Fachdiskussionen der Meisterseminare zur Produktionstechnik aus den Jahren 1995 bis 2000, Beratungsgespraechen fuer Mitgliedsunternehmen oder wurden dem Bundesverband Kalksandsteinindustrie eV freundlicherweise fuer die Gemeinschaftsarbeit zur Verfuegung gestellt. (orig.)

  16. Profiling and quantitative evaluation of three Nickel-Coated magnetic matrices for purification of recombinant proteins: lelpful hints for the optimized nanomagnetisable matrix preparation

    Directory of Open Access Journals (Sweden)

    Zarei Saeed

    2011-08-01

    Full Text Available Abstract Background Several materials are available in the market that work on the principle of protein magnetic fishing by their histidine (His tags. Little information is available on their performance and it is often quoted that greatly improved purification of histidine-tagged proteins from crude extracts could be achieved. While some commercial magnetic matrices could be used successfully for purification of several His-tagged proteins, there are some which have been proved to operate just for a few extent of His-tagged proteins. Here, we address quantitative evaluation of three commercially available Nickel nanomagnetic beads for purification of two His-tagged proteins expressed in Escherichia coli and present helpful hints for optimized purification of such proteins and preparation of nanomagnetisable matrices. Results Marked differences in the performance of nanomagnetic matrices, principally on the basis of their specific binding capacity, recovery profile, the amount of imidazole needed for protein elution and the extent of target protein loss and purity were obtained. Based on the aforesaid criteria, one of these materials featured the best purification results (SiMAG/N-NTA/Nickel for both proteins at the concentration of 4 mg/ml, while the other two (SiMAC-Nickel and SiMAG/CS-NTA/Nickel did not work well with respect to specific binding capacity and recovery profile. Conclusions Taken together, functionality of different types of nanomagnetic matrices vary considerably. This variability may not only be dependent upon the structure and surface chemistry of the matrix which in turn determine the affinity of interaction, but, is also influenced to a lesser extent by the physical properties of the protein itself. Although the results of the present study may not be fully applied for all nanomagnetic matrices, but provide a framework which could be used to profiling and quantitative evaluation of other magnetisable matrices and also

  17. AUTOSOMAL RECESSIVE PERIPHERAL NEUROPATHY WITH NEUROMYOTONIA (ARAN-NM: DESCRIPTION OF A CLINICAL CASE CONFIRMED BY A MUTATION IN THE HINT1 GENE

    Directory of Open Access Journals (Sweden)

    Olga A. Klochkova

    2017-01-01

    Full Text Available Autosomal recessive  peripheral neuropathy with neuromyotonia  (ARAN-NM  is a relatively newly described  disease associated  with mutations  in the HINT1 gene.  It accounts  for a significant  part of the poorly  differentiated  forms  of axonal polyneuropathies.  We present the first in Russia description of the genetically confirmed case of ARAN-NM in a boy aged 14 years and 11 months without the hereditary-tainted anamnesis. On presentation,  the patient experienced  progressive  distal muscular weakness, asymmetric foot deformity,  gait disorders  and minimal manifestations  of neuromyotonia  (stiffness  in the fingers.  During examination,  we detected an increase in the level of creatine phosphokinase up to 635 U/l, a disturbance of conduction of motor and, to a lesser extent, sensory fibers  of  the  peripheral  nerves  (according  to  the  stimulation  electromyography,  EMG,  denervation-reinnervation  changes,  single positive acute waves, fibrillation potentials, complex repeated discharge (according to the data of needle EMG. In the study of exome, a homozygous mutation c.110G>C, p.R37P was determined in exon 01 of the HINT1 gene, which confirmed the presence of ARAN-NM. A molecular-genetic  examination of the patient's immediate relatives was carried out. The described case is compared with literature data. An overview of currently available information on ARAN-NM is provided. Diagnostic criteria of the disease are presented.

  18. Nonminimal hints for asymptotic safety

    Science.gov (United States)

    Eichhorn, Astrid; Lippoldt, Stefan; Skrinjar, Vedran

    2018-01-01

    In the asymptotic-safety scenario for gravity, nonzero interactions are present in the ultraviolet. This property should also percolate into the matter sector. Symmetry-based arguments suggest that nonminimal derivative interactions of scalars with curvature tensors should therefore be present in the ultraviolet regime. We perform a nonminimal test of the viability of the asymptotic-safety scenario by working in a truncation of the renormalization group flow, where we discover the existence of an interacting fixed point for a corresponding nonminimal coupling. The back-coupling of such nonminimal interactions could in turn destroy the asymptotically safe fixed point in the gravity sector. As a key finding, we observe nontrivial indications of stability of the fixed-point properties under the impact of nonminimal derivative interactions, further strengthening the case for asymptotic safety in gravity-matter systems.

  19. Avalik ruum : kaotatud võimaluste ruum? = Public space : a space of lost opportunities? / Aili Vahtrapuu

    Index Scriptorium Estoniae

    Vahtrapuu, Aili, 1950-

    2011-01-01

    Avalikust linnaruumist, selle kahanemisest. Arhitektuurist ja kunstist. Riigi tellimusena valmivast avaliku ruumi kunstist, mille eesmärgiks on avaliku ruumi rikastamine ja inimsõbralikuma keskkonna loomine. Kunsti ja arhitektuuri suhestumisest Tallinna linnaruumis, kaotatud avaliku ruumi tagasivõitmise võimalusest

  20. Valdek Palli mälestusõhtu ja fond / Aili Künstler

    Index Scriptorium Estoniae

    Künstler, Aili

    2013-01-01

    Ersa-mokša kultuuriühingu Sjatko eestvedamisel ja TLÜ muuseumi kaaskorraldusel toimus TLÜ teadusinfokeskuses eesti keeleteadlase, rahvusvaheliselt tunnustatud fenno­ugristi ja TLÜ esimese emeriitprofessori Valdek Palli mälestusõhtu. TLÜs asutati professor Valdek Palli nimeline fond soome-ugri teaduse ja kultuuriprojektide toetuseks

  1. Voluntary associations and reconstruction of the neighbourhood / Aili Aarelaid-Tart

    Index Scriptorium Estoniae

    Aarelaid-Tart, Aili, 1947-2014

    1996-01-01

    Sisaldab jooniseid: Network of socio-cultural institutions in the neighbourhood during late-Soviet period in Estonia ; Network of socio-cultural institutions to solve real problems in the neighbourhood during late-Soviet period in Estonia ; Network of socio-cultural institutions to solve problems in the neighbourhood in 1995 (Estonian case)

  2. Vanemaealiste ränne Eestis = Migration of older people in Estonia / Ailis Tammur

    Index Scriptorium Estoniae

    Tammur, Ailis

    2007-01-01

    Vanemaealiste inimeste rände uurimisel olid uuritavateks kaks rahvastikurühma - vanemas tööeas inimesed (50-64-aastased) ja pensioniealised (vähemalt 65-aastased). Rändeintensiivsus ja suunad. Lisatud graafikud ja tabelid

  3. Revolutsioonid väärtusmaailmade teisendajatena / Aili Aarelaid-Tart, Indrek Tart

    Index Scriptorium Estoniae

    Aarelaid-Tart, Aili, 1947-2014

    2008-01-01

    Revolutsiooni mõistest ja analüüsist sotsiaalteaduses ning väärtusmaailmade teisenemisest Eestis laulva revolutsiooni tulemina. Tabel: Väärtusjärjestused Eestis 1991-2005. Joonised: Alusväärtuste stabiilne tuumik Eestis aastatel 1991-2005; Suurimate muutustega väärtused Eestis aastatel 1991-2005; Revolutsiooniliste väärtuste dünaamika Eestis aastail 1991-2005. Lisa: Täielik väärtusjärjestusi mõõdistavate ankeetküsimuste loend

  4. Eestlane Muutuvas Maailmas. Seisusühiskonnast kodanikuühiskonda / Aili Aarelaid-Tart

    Index Scriptorium Estoniae

    Aarelaid-Tart, Aili, 1947-2014

    2008-01-01

    Arvustus: Jansen, Ea. Eestlane muutuvas ajas: seisusühiskonnast kodanikuühiskonda / [edited by Tõnu Tannberg, Jaanus Arukaevu & Helina Tamman]. Tartu, Eesti Ajalooarhiiv, 2007. ISBN 978-9985-858-57-8

  5. Uskumatu, kuid tõsi! Londoni allmaaraudtee / Aili Pedusaar, Heino Pedusaar

    Index Scriptorium Estoniae

    Pedusaar, Aili

    1999-01-01

    Londoni allmaaraudtee rajamisest. Seaduslik teostamisluba anti 1854. asutatud Metropolitan Company projektile. Pidulik proovisõit toimus 9. I 1863. Maailma esimene elektri-allmaaraudtee läks käiku 4. X 1890. B. Karger-Deckeri raamatu "Wunderwerke von Menchenhand"(Leipzig, 1963) aineil

  6. Mis saab ESTERMist? / Tiina Soon, Peeter Päll, Ivi Papstel ; interv. Aili Künstler

    Index Scriptorium Estoniae

    Soon, Tiina

    2008-01-01

    Eesti Õiguskeskuse loodud andmebaasist ESTERM. Vastavad EKI terminoloogiaosakonna juhataja Tiina Soon, EKI keelekorraldusosakonna vanemteadur Peeter Päll, Justiitsministeeriumi avalike suhete talituse juhataja Ivi Papstel

  7. Recommender System for Learning SQL Using Hints

    Science.gov (United States)

    Lavbic, Dejan; Matek, Tadej; Zrnec, Aljaž

    2017-01-01

    Today's software industry requires individuals who are proficient in as many programming languages as possible. Structured query language (SQL), as an adopted standard, is no exception, as it is the most widely used query language to retrieve and manipulate data. However, the process of learning SQL turns out to be challenging. The need for a…

  8. Taso Mähar : galerii / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Taso Mähari projekteeritud töödest. 1997. a. valminud restorani Exit sisekujundusest, mis pälvis Eesti Sisearhitektide Liidu aastapreemia. Metallist ja ühest tükist väljapainutatud toolist ja samas laadis tehtud diivanist aastast 1989, mis leidsid 1992. a. aastauudistena äramärkimist ajakirjas Abitare. T. Mähari kommentaarid. 3 värv. ill

  9. Nursing knowledge: hints from the placebo effect.

    Science.gov (United States)

    Zanotti, Renzo; Chiffi, Daniele

    2017-07-01

    Nursing knowledge stems from a dynamic interplay between population-based scientific knowledge (the general) and specific clinical cases (the particular). We compared the 'cascade model of knowledge translation', also known as 'classical biomedical model' in clinical practice (in which knowledge gained at population level may be applied directly to a specific clinical context), with an emergentist model of knowledge translation. The structure and dynamics of nursing knowledge are outlined, adopting the distinction between epistemic and non-epistemic values. Then, a (moderately) emergentist approach to nursing knowledge is proposed, based on the assumption of a two-way flow from the general to the particular and vice versa. The case of the 'placebo effect' is analysed as an example of emergentist knowledge. The placebo effect is usually considered difficult to be explained within the classical biomedical model, and we underscore its importance in shaping nursing knowledge. In fact, nurses are primarily responsible for administering placebo in the clinical setting and have an essential role in promoting the placebo effect and reducing the nocebo effect. The beliefs responsible for the placebo effect are as follows: (1) interactive, because they depend on the relationship between patients and health care professionals; (2) situated, because they occur in a given clinical context related to certain rituals; and (3) grounded on higher order beliefs concerning what an individual thinks about the beliefs of others. It is essential to know the clinical context and to understand other people's beliefs to make sense of the placebo effect. The placebo effect only works when the (higher order) beliefs of doctors, nurses and patients interact in a given setting. Finally, we argue for a close relationship between placebo effect and nursing knowledge. © 2016 John Wiley & Sons Ltd.

  10. [Modifying our "obesogenic" environment: which hints?].

    Science.gov (United States)

    Masciangelo, M L; Golay, A

    2006-03-29

    Overweight is nowadays a major problem of public health in Switzerland. Swiss people eat too much, too much fat, sugar and salt! Most efficient public health strategies are global and also apply to environmental modifications, an important determinant to change individual behaviours. Today, our environment is "obesogenic": unlimited access to food, food industry marketing, lifestyle changes. As global programmes for smoking cessation and cardiovascular diseases prevention, it is urgent to propose interventions taking into account all environmental factors which could support individuals in their efforts of changes.

  11. Practical Hints on Greek and Latin

    Science.gov (United States)

    Jopes, James

    1978-01-01

    A discussion of some of the difficulties and procedures in translating classical quotations occurring in a modern text. Some of the topics covered are: use of published translations, transliteration from ancient Greek, and non-classical idioms such as medieval and botanical Latin. (AMH)

  12. Design Copyright: The Latest Judicial Hint

    OpenAIRE

    Scott Hemphill; Jeannie Suk

    2013-01-01

    The most intriguing aspect of the debate over fashion copyright is the occasion it presents for rethinking the expansive copyright law we currently have. C. Scott Hemphill (Columbia Law) & Jeannie Suk (Harvard Law)

  13. Kerjav kunstnik / Anna Hints, Maria Rõhu

    Index Scriptorium Estoniae

    Hints, Anna, 1982-

    2011-01-01

    Tallinna Linnagaleriis oli 17.03.-10.04.2011 avatud Anna Hintsi ja Maria Rõhu näitus "Nälg". Autorid näituse taotlusest, raha taotlemisest, aktsioonist "Kerjav kunstnik", külastajate suhtumisest sellesse. Näituse aruanne

  14. Observational hints on the Big Bounce

    International Nuclear Information System (INIS)

    Mielczarek, Jakub; Kurek, Aleksandra; Szydłowski, Marek; Kamionka, Michał

    2010-01-01

    In this paper we study possible observational consequences of the bouncing cosmology. We consider a model where a phase of inflation is preceded by a cosmic bounce. While we consider in this paper only that the bounce is due to loop quantum gravity, most of the results presented here can be applied for different bouncing cosmologies. We concentrate on the scenario where the scalar field, as the result of contraction of the universe, is driven from the bottom of the potential well. The field is amplified, and finally the phase of the standard slow-roll inflation is realized. Such an evolution modifies the standard inflationary spectrum of perturbations by the additional oscillations and damping on the large scales. We extract the parameters of the model from the observations of the cosmic microwave background radiation. In particular, the value of inflaton mass is equal to m = (1.7±0.6)·10 13 GeV. In our considerations we base on the seven years of observations made by the WMAP satellite. We propose the new observational consistency check for the phase of slow-roll inflation. We investigate the conditions which have to be fulfilled to make the observations of the Big Bounce effects possible. We translate them to the requirements on the parameters of the model and then put the observational constraints on the model. Based on assumption usually made in loop quantum cosmology, the Barbero-Immirzi parameter was shown to be constrained by γ < 1100 from the cosmological observations. We have compared the Big Bounce model with the standard Big Bang scenario and showed that the present observational data is not informative enough to distinguish these models

  15. Election Year Hints at Shifts for Unions

    Science.gov (United States)

    Honawar, Vaishali; Keller, Bess

    2008-01-01

    The National Education Association is poised for a change in leadership this year as its president of six years, Reg Weaver, bumps up against term limits. Now, speculation is widespread that Edward J. McElroy, his counterpart at the American Federation of Teachers, might not seek re-election in July. The possible exit of Mr. McElroy--and the…

  16. HINTS IN OMABE BASED SCULPTURE INSTALLATIONS ...

    African Journals Online (AJOL)

    ASOGWA IFEANYI

    2017-02-02

    Feb 2, 2017 ... to develop both new methods of inquiry and appropriate forms of ... sculpture, music, dance, poetry, movement, dialogue and painting. ... were feared and respected by everybody in the society, including women and children.

  17. Correlation of Fracture Behavior With Microstructure in Friction Stir Welded, and Spin Formed AI-Li 2195 Domes

    Science.gov (United States)

    Tayon, Wesley A.; Domack, Marcia S.; Hales, Stephen J.

    2012-01-01

    Single-piece, spin-formed domes manufactured from friction stir welded (FSW) plates of Al-Li alloy 2195 have the potential to reduce the cost of fabricating cryogenic propellant tanks. Mechanical properties in the completed domes can be related directly to the final material condition and the microstructures developed. However, these new fabrication techniques have resulted in unexpected material challenges, such as abnormal grain growth in the weld nugget and the propensity for fracture in the adjacent thermo-mechanically affected zone (TMAZ). In this study, the microstructure and texture transformations within the TMAZ are related to fracture location in the vicinity of the weldment. The texture variations in the TMAZ are caused primarily by the varying amounts of shear deformation introduced during the FSW process. Grain morphology and microtexture characteristics are examined as a function of location in the TMAZ via electron backscatter diffraction (EBSD). A strong correlation between fracture location and the presence of texture banding in the TMAZ is observed. The fracture path tends to follow a distinct region of low Taylor Factor (TF) grains.

  18. Ise loodud elu. Soome ITE-kunstnikud Tallinnas : Outsider-kunst / Erkki Pirtola ; tõlk. Aili Künstler

    Index Scriptorium Estoniae

    Pirtola, Erkki

    2003-01-01

    Rahvusvahelisel autsaiderite ja art brut' näitus "Solvates meduusi" Tallinna Kunstihoones ja Kullo galeriis esinevatest soome kunstnikest Ilmari Immpu Salminenist, Johannes Setäläst, Markku Susimäkist, Väino Ojast, Petri Martikainenist, Juha Vanhanenist

  19. Mehed, kes ei ole kunagi käega löönud / Rain Pikand, Urmas Lilleorg ; interv. Krista Dudarenko

    Index Scriptorium Estoniae

    Pikand, Rain

    2008-01-01

    Reklaamiagentuur Division pälvis konkursil "Kuldmuna" Grand Prix' ja Aasta Agentuuri tiitli. Agentuuri loomisest, tähtsamatest töödest, edu tagamaadest, kaasaegses reklaamimaailmas valitsevatest suundadest

  20. Mari Koger : seina sisse ehitatud akvaariumiga poissmehekodu / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    80-ruutmeetrine poissmehekorter Viimsi uues elamus. Elutoa ja vannitoa vahelises seinas paikneb kahelt poolt vaadeldav akvaarium. Magamistoa üks seintest on ehitatud vanadest tellistest. Sisearhitekt Mari Koger, tema kommentaarid. Ill.: plaan, 9 värv. vaadet

  1. HINT for Squint: A Computer Reliant Diagnostic Aid for Strabismus

    OpenAIRE

    Gieszl, Louis R.; Morris, Jacqueline; Guyton, David L.

    1983-01-01

    This paper provides an outline of methods used for the implementation of a computer reliant diagnostic aid in the medical specialty of Ophthalmology. Some problems have been associated with many previous diagnostic models. A careful review indicates that the most serious problems were:

  2. Short views and hints on information, knowledge and scenarios

    DEFF Research Database (Denmark)

    Kristiansson, Michael

    2011-01-01

    This article discusses information and knowledge in relation to scenario planning (van der Heijden) and considers the type of information that is relied on/included as well as the nature of knowledge produced by the scenario planning sequence. In addition, the chief tools and processes drawn upon...

  3. Phenomenological Hints from a Class of String Motivated Model Constructions

    Directory of Open Access Journals (Sweden)

    Hans Peter Nilles

    2015-01-01

    Full Text Available We use string theory constructions towards the generalisation of the supersymmetric standard model of strong and electroweak interactions. Properties of the models depend crucially on the location of fields in extradimensional compact space. This allows us to extract some generic lessons for the phenomenological properties of the low energy effective action. Within this scheme we present a compelling model based on local grand unification and mirage mediation of supersymmetry breakdown. We analyse the properties of the specific model towards its possible tests at the LHC and the complementarity to direct dark matter searches.

  4. Tiina Mang : vanalinna korter muutus visuaalselt suuremaks / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    74-ruutmeetrine vanalinna korter, mõeldud kahele inimesele, kellest üks töötab kodus. Enamik mööblist on valmistatud eritellimusel. Sisearhitekt Tiina Mang, tema kommentaarid. Ill.: plaan, 3 värv. vaadet

  5. Observational hints of radial migration in disc galaxies from CALIFA

    Science.gov (United States)

    Ruiz-Lara, T.; Pérez, I.; Florido, E.; Sánchez-Blázquez, P.; Méndez-Abreu, J.; Sánchez-Menguiano, L.; Sánchez, S. F.; Lyubenova, M.; Falcón-Barroso, J.; van de Ven, G.; Marino, R. A.; de Lorenzo-Cáceres, A.; Catalán-Torrecilla, C.; Costantin, L.; Bland-Hawthorn, J.; Galbany, L.; García-Benito, R.; Husemann, B.; Kehrig, C.; Márquez, I.; Mast, D.; Walcher, C. J.; Zibetti, S.; Ziegler, B.; Califa Team

    2017-07-01

    Context. According to numerical simulations, stars are not always kept at their birth galactocentric distances but they have a tendency to migrate. The importance of this radial migration in shaping galactic light distributions is still unclear. However, if radial migration is indeed important, galaxies with different surface brightness (SB) profiles must display differences in their stellar population properties. Aims: We investigate the role of radial migration in the light distribution and radial stellar content by comparing the inner colour, age, and metallicity gradients for galaxies with different SB profiles. We define these inner parts, avoiding the bulge and bar regions and up to around three disc scale lengths (type I, pure exponential) or the break radius (type II, downbending; type III, upbending). Methods: We analysed 214 spiral galaxies from the CALIFA survey covering different SB profiles. We made use of GASP2D and SDSS data to characterise the light distribution and obtain colour profiles of these spiral galaxies. The stellar age and metallicity profiles were computed using a methodology based on full-spectrum fitting techniques (pPXF, GANDALF, and STECKMAP) to the Integral Field Spectroscopic CALIFA data. Results: The distributions of the colour, stellar age, and stellar metallicity gradients in the inner parts for galaxies displaying different SB profiles are unalike as suggested by Kolmogorov-Smirnov and Anderson-Darling tests. We find a trend in which type II galaxies show the steepest profiles of all, type III show the shallowest, and type I display an intermediate behaviour. Conclusions: These results are consistent with a scenario in which radial migration is more efficient for type III galaxies than for type I systems, where type II galaxies present the lowest radial migration efficiency. In such a scenario, radial migration mixes the stellar content, thereby flattening the radial stellar properties and shaping different SB profiles. However, in light of these results we cannot further quantify the importance of radial migration in shaping spiral galaxies, and other processes, such as recent star formation or satellite accretion, might play a role. Based on observations collected at the Centro Astronómico Hispano Alemán (CAHA) at Calar Alto, operated jointly by the Max-Planck Institut für Astronomie and the Instituto de Astrofísica de Andalucía (CSIC).Table 1 is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/604/A4

  6. Observational hints of radial migration in disc galaxies from CALIFA

    NARCIS (Netherlands)

    Ruiz-Lara, T.; Pérez, I.; Florido, E.; Sánchez-Blázquez, P.; Méndez-Abreu, J.; Sánchez-Menguiano, L.; Sánchez, S. F.; Lyubenova, M.; Falcón-Barroso, J.; van de Ven, G.; Marino, R. A.; de Lorenzo-Cáceres, A.; Catalán-Torrecilla, C.; Costantin, L.; Bland-Hawthorn, J.; Galbany, L.; García-Benito, R.; Husemann, B.; Kehrig, C.; Márquez, I.; Mast, D.; Walcher, C. J.; Zibetti, S.; Ziegler, B.

    2017-01-01

    Context. According to numerical simulations, stars are not always kept at their birth galactocentric distances but they have a tendency to migrate. The importance of this radial migration in shaping galactic light distributions is still unclear. However, if radial migration is indeed important,

  7. Ageing collider throws up hint or dark matter

    CERN Multimedia

    Ananthaswamy, Anil

    2008-01-01

    "Never mind the Large Hadron Collider at CERN, its ageing predecessor may have discovered a new and unexpected kind of particle. The announcement last week from the Tevatron particle accelerator at Fermilab in Batavai, Illinois, provided some excitement amid the frustration of ongoing repairs to the LHC."

  8. A "g" beyond "Homo Sapiens"? Some Hints and Suggestions

    Science.gov (United States)

    Lee, James J.

    2007-01-01

    This article proposes that a complete account of cognitive evolution may have to accommodate a domain-general source of variance in mental abilities accounting for differences among primate taxa. Deaner, van Schaik, and Johnson [Deaner, R.O., van Schaik, C.P. and Johnson, V.E. (2006). Do some taxa have better domain-general cognition than others?…

  9. Hints for electric-field compensation in multicell resonant structures

    Energy Technology Data Exchange (ETDEWEB)

    Fernandes, P; Parodi, R

    1981-03-31

    We propose a lumped-parameter equivalent circuit for a TM/sub 01/ multicell standing wave accelerating structure with full end cells. By the suggested model we can predict the amount of end cell frequency compensation needed to achieve field flatness in the highest mode of the structure.

  10. An Impending geomagnetic transition? Hints from the past.

    Directory of Open Access Journals (Sweden)

    Carlo eLAJ

    2015-10-01

    Full Text Available The rapid decrease of the geomagnetic field intensity in the last centuries has led to speculations that an attempt to a reversal or an excursion might be under way. Here we investigate this hypothesis by examining past records of geomagnetic field intensity obtained from sedimentary cores and from the study of cosmogenic nuclides. The selected records describe geomagnetic changes with an unprecedented temporal resolution between 20 and 75 kyr B.P. We find that some aspects of the present-day geomagnetic field have some similarities with those documented for the Laschamp excursion 41 kyr ago. Under the assumption that the dynamo processes for an eventual future reversal or excursion would be similar to those of the Laschamp excursion, we tentatively suggest that, whilst irreversible processes that will drive the geodynamo into a polarity change may have already started, a reversal or an excursion should not be expected before 500 to 1000 years.

  11. An impending geomagnetic transition? Hints from the past

    OpenAIRE

    Laj, Carlo; Kissel, Catherine

    2015-01-01

    The rapid decrease of the geomagnetic field intensity in the last centuries has led to speculations that an attempt to a reversal or an excursion might be under way. Here we investigate this hypothesis by examining past records of geomagnetic field intensity obtained from sedimentary cores and from the study of cosmogenic nuclides. The selected records describe geomagnetic changes with an unprecedented temporal resolution between 20 and 75 kyr B.P. We find that some aspects of the present-day...

  12. Learning To Learn: 15 Vocabulary Acquisition Activities. Tips and Hints.

    Science.gov (United States)

    Holden, William R.

    1999-01-01

    This article describes a variety of ways learners can help themselves remember new words, choosing the ones that best suit their learning styles. It is asserted that repeated exposure to new lexical items using a variety of means is the most consistent predictor of retention. The use of verbal, visual, tactile, textual, kinesthetic, and sonic…

  13. Food Safety and Quality Control: Hints from Proteomics

    Directory of Open Access Journals (Sweden)

    Angelo D'Alessandro

    2012-01-01

    Full Text Available Over the last decade, proteomics has been successfully applied to the study of quality control in production processes of food (including meat, wine and beer, transgenic plants and milk and food safety (screening for food-derived pathogens. Indeed, food quality and safety and their influence on the health of end consumers have growingly become a founding principle in the international agenda of health organizations. The application of proteomics in food science was at first characterized by exploratory analyses of food of various origin (bovine, swine, chicken or lamb meat, but also transgenic food such as genetically modified maize, for example and beverages (beer, wine, in parallel to the genomic and transcriptomic approaches seeking determination of quantitative trait loci. In the last few years, technical improvements such as microbial biotyping strategies have growingly allowed proteomicists to address the safety issue as well. The newly introduced technical improvements (instrumentation characterized by higher sensitivity such as mass spectrometers have paved the way for the individuation of food-contaminating pathogens in a fast and efficient workflow which is mandatory in industrial food production chains.

  14. HINT-KB: The human interactome knowledge base

    KAUST Repository

    Theofilatos, Konstantinos A.; Dimitrakopoulos, Christos M.; Kleftogiannis, Dimitrios A.; Moschopoulos, Charalampos N.; Papadimitriou, Stergios; Likothanassis, Spiridon D.; Mavroudi, Seferina P.

    2012-01-01

    Proteins and their interactions are considered to play a significant role in many cellular processes. The identification of Protein-Protein interactions (PPIs) in human is an open research area. Many Databases, which contain information about

  15. Using peer instruction with hints in introductory business statistics

    NARCIS (Netherlands)

    Ding, Ning; Xu, Xiaoyan

    2014-01-01

    Abstract:Purpose – Peer instruction has been widely adopted as an instructional method in higher education. However, due to students' different preconceptions, the authors argued that peer instruction is not a panacea in international business education when students' prior knowledge extensively

  16. What Caused the Recession of 2008? Hints from Labor Productivity

    OpenAIRE

    Casey Mulligan

    2009-01-01

    A labor market tautology says that any change in labor usage can be decomposed into a movement along a marginal productivity schedule and a shift of the schedule. I calculate this decomposition for the recession of 2008, assuming an aggregate Cobb-Douglas marginal productivity schedule, and find that all of the decline in employment and hours since December 2007 is a movement along the schedule. This finding suggests that a reduction in labor supply and/or an increase in labor market distorti...

  17. Mari Koger : "Arhitekte on palju. Tuleb leida õige" / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Mari Koger (sünd. 1973) kodu kujundamisest, planeerimisest, valgustusest, värvidest, suhtlemisest kliendiga. Mari Kogerist, loetletud tema tehtud ühiskondlike ruumide sisekujundused aastast 2002. M. Koger töötab Boom.ee OÜ-s. Ill.: M. Kogeri värv. portree

  18. Remembering Multiple Passwords by Way of Minimal-Feedback Hints

    DEFF Research Database (Denmark)

    Hertzum, Morten

    2004-01-01

    Passwords are a prominent mechanism for user authentication but entail a conflict between ease of use and security in that passwords must be both easy to remember for the password holder and difficult to guess for everybody else. To support users in remembering their passwords minimal-feedback...

  19. Brotze väljaande filoloogilisi probleeme / Mati Hint

    Index Scriptorium Estoniae

    Hint, Mati

    2007-01-01

    Rets. rmt. : Johann Christoph Brotze. Estonica. Koostanud / Herausgegeben von Ants Hein, Ivar Leimus, Raimo Pullat, Ants Viires. Projektijuht ja vastutav toimetaja : Raimo Pullat. tõlge eesti keelde: Tõnis Liibek, Ivar Leimus, tõlge saksa keelde: Aigi Heero, Ene Rõngelep. Kujundus: Andres Tali. Tallinn : Estopol OÜ, 2006. XXXVI, 619 lk. Teoses esinevaid keele- ja kohanimeprobleeme

  20. Aet Piel : oluline sisekujunduselement on viltune sein / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Poolkaares ehitatud korterelamus on Aet Pieli kujundatud korteris üks sein viltu. Esmapilgul häirivana mõjunud sein sai oluliseks sisekujunduselemendiks. Eritellimusel valmistatud mööbel on tammepuidust. A. Pieli kommentaarid. Ill.: plaan enne ja nüüd, 9 värv. vaadet

  1. Sanitation and recultivation of the Endlhausen landfill. Experience and hints

    Energy Technology Data Exchange (ETDEWEB)

    Hoerich, O; Rieger, W

    1986-02-01

    A landfill located in a former gravel pit was covered once 300,000 t of domestic refuse had been dumped. Drain pipes were laid for degassing the landfill. A clay layer was used to prevent surface water inroads. The article explains details and approaches. The cost are some DM 900,000 at an area of 3 ha. Grassing and planting will follow.

  2. 200 more puzzling physics problems with hints and solutions

    CERN Document Server

    Gnädig, Péter; Vigh, Máté

    2016-01-01

    Like its predecessor, 200 Puzzling Physics Problems, this book is aimed at strengthening students' grasp of the laws of physics by applying them to situations that are practical, and to problems that yield more easily to intuitive insight than to brute-force methods and complex mathematics. The problems are chosen almost exclusively from classical, non-quantum physics, but are no easier for that. They are intriguingly posed in accessible non-technical language, and require readers to select an appropriate analysis framework and decide which branches of physics are involved. The general level of sophistication needed is that of the exceptional school student, the good undergraduate, or the competent graduate student; some physics professors may find some of the more difficult questions challenging. By contrast, the mathematical demands are relatively minimal, and seldom go beyond elementary calculus. This further book of physics problems is not only instructive and challenging, but also enjoyable.

  3. Riemannian geometry of Hamiltonian chaos: hints for a general theory.

    Science.gov (United States)

    Cerruti-Sola, Monica; Ciraolo, Guido; Franzosi, Roberto; Pettini, Marco

    2008-10-01

    We aim at assessing the validity limits of some simplifying hypotheses that, within a Riemmannian geometric framework, have provided an explanation of the origin of Hamiltonian chaos and have made it possible to develop a method of analytically computing the largest Lyapunov exponent of Hamiltonian systems with many degrees of freedom. Therefore, a numerical hypotheses testing has been performed for the Fermi-Pasta-Ulam beta model and for a chain of coupled rotators. These models, for which analytic computations of the largest Lyapunov exponents have been carried out in the mentioned Riemannian geometric framework, appear as paradigmatic examples to unveil the reason why the main hypothesis of quasi-isotropy of the mechanical manifolds sometimes breaks down. The breakdown is expected whenever the topology of the mechanical manifolds is nontrivial. This is an important step forward in view of developing a geometric theory of Hamiltonian chaos of general validity.

  4. Tunne bossanova plaadiümbriselt / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2004-01-01

    Kahekorruseline eramu (285 m2), mille merepoolne sein on klaasist. Läbiv idee - silmside loodusega. Arhitekt ja sisearhitekt Tarmo Piirmets, tema kommentaar. Ill.: I ja II korruse plaan, 13 värv. vaadet

  5. Taso Mähar : avatud vannitoaga vanalinna korter / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Modernne korter (220 m2). Sisearhitekt Taso Mähar, tema kommentaarid. Kogu korteri ulatuses on sisekujundusmaterjalidena kasutatud väärispuitu, metalli, marmorit ja klaasi. T. Mähari projekteeritud on trepp ja piirded, kamin, baarilett ja õhukesed alumiiniumraamidel mattklaasidega uksed. Ill.: I ja II korruse plaan, 8 värv. vaadet

  6. New planet hints at life in the stars

    CERN Multimedia

    Dalton, A W

    2002-01-01

    Astronomers have detected a distant planet 100 light years from Earth, circling Tau1 Gruis, its star, in the constellation of Grus (the crane). The planet, similar in appearance to Jupiter, is three times as far away from its star as the Earth is from the Sun and takes four years to revolve around the star, in a roughly circular orbit. Scientists believe this type of planetary orbit is the most promising for finding worlds that contain life (1 page).

  7. New physics hints in B decays and collider outlook

    Indian Academy of Sciences (India)

    Less noticed is the difference in direct CPV (DCPV) asymmetries in B0 ... Our working picture is that squarks are relatively degenerate at some ... We stress that the new (and unique!) ..... [1] See http://mlm.home.cern.ch/mlm/FlavLHC.html.

  8. "To Improve upon Hints of Things": Illustrating Isaac Newton.

    Science.gov (United States)

    Schilt, Cornelis J

    2016-01-01

    When Isaac Newton died in 1727 he left a rich legacy in terms of draft manuscripts, encompassing a variety of topics: natural philosophy, mathematics, alchemy, theology, and chronology, as well as papers relating to his career at the Mint. One thing that immediately strikes us is the textuality of Newton's legacy: images are sparse. Regarding his scholarly endeavours we witness the same practice. Newton's extensive drafts on theology and chronology do not contain a single illustration or map. Today we have all of Newton's draft manuscripts as witnesses of his working methods, as well as access to a significant number of books from his own library. Drawing parallels between Newton's reading practices and his natural philosophical and scholarly work, this paper seeks to understand Newton's recondite writing and publishing politics.

  9. DEMYSTIFYING QUANTUM MECHANICS: Will there be hints from LHC?

    CERN Multimedia

    CERN. Geneva

    2007-01-01

    All modern theories for particles, forces and even space-time itself, use the framework provided by quantum mechanics. The Standard Model is a quantized field theory. Even superstring theory is based on quantum mechanics. There is something odd about quantum mechanics: it brilliantly allows us to predict the outcome of experiments, yet it gives confusing statements about what really is going on inside particles and fields. Suppose we would be asking for a theory that allows us to describe what actually happens in less ambiguous terms, without destroying the magnificent successes of quantum mechanics, would this help us to answer some of the great mysteries of theoretical elementary particle physics?Organiser(s): L. Alvarez-Gaume / PH-THNote: * Tea & coffee will be served at 16:00.

  10. Nafta hinna kõikumine solgutab Euroopa lennufirmade aktsiaid / Annika Matson

    Index Scriptorium Estoniae

    Matson, Annika, 1976-

    2004-01-01

    Nafta hinnatõus langetab lennufirmade aktsiate hindasid. Kommenteerib Estonian Air'i asepresident Leela Lilleorg. Graafikud: Euroopa suuremate lennufirmade aktsiad nafta tõmbetuules; Nafta hind rahvusvahelisel naftabörsil Londonis

  11. Tartus veeresid Kuldmunad ja Kandilised Munad / Liivi Shein

    Index Scriptorium Estoniae

    Šein, Liivi

    2007-01-01

    "Kuldmuna 2007" võistlusel hinnati seekord reklaami- ja disainitöid eraldi. Aasta agentuuriks tunnistati reklaamibüroo Division. Reklaamivõistluse žürii esimees Urmas Lilleorg, disaini žürii eesotsas Margus Klaar

  12. Tänukiri

    Index Scriptorium Estoniae

    2000-01-01

    Tulemusliku töö eest tänukirjaga autasustatud TPÜ töötajad ja külalislektorid: Angela Arraste, Cécile Eliziere, Margus Harak, Aili Kants, Edgar Karofeld, Aili Kelam, Wolf Peter Klein, Jüri Kruusvall, Marek Kuzmin, Viivi Maanso, Avo Petrauts, Anne Rooste, Helve Siivo, Leida Talts, Aili Tamm, Anu Toots, Ülo Ugaste, Urve Väljas, Paul Ruudi / allikas : TPÜ rektori käskkiri, 13. oktoober 2000

  13. Памятник композитору Эдуарду Тубину, Тарту = Monument to the composer Eduard Tubin, Tartu / Илья Архипенко

    Index Scriptorium Estoniae

    Архипенко, Илья

    2010-01-01

    Eduard Tubina monumendist Tartus. Arhitekt Veronika Valk (Zizi & Yoyo), skulptor Aili Vahtrapuu. Kompleks koosneb kahest elemendist: traditsioonilisest mälestusmärgist ja interaktiivsest installatsioonist

  14. 26. V võõrustas Läti suursaadik Edgars Skuja Tallinnas Tõnismäel Liivimaa aja- ja kultuuriloo huvilist üldsust... / Aili Künstler

    Index Scriptorium Estoniae

    Künstler, Aili

    2005-01-01

    Antakse välja Riias tegutsenud baltisaksa kultuuriloolase Johann Christoph Brotze (1742-1823) siinset arhitektuuri, eluolu, inimtüüpe, maastikku, linnavaateid jms. kujutava materjaliga köide. J. Chr. Brotze joonistuste hulgast teevad valiku ja tema saksakeelset teksti kommenteerivad peatoimetaja Raimo Pullat, Ivar Leimus, Ants Hein, Ants Viires, Lauri Suurmaa ja Tõnis Liibek

  15. Kas omakeelsel haridusel ja teadusel on tulevikku? / Kirsti Siitonen, Jolanta Zabarskaite, Josep Soler-Carbonell, Rainer Enrique Hamel ; intervjueerinud Peep Nemvalts ; tõlkinud Doris Kareva, Aili Künstler

    Index Scriptorium Estoniae

    2011-01-01

    TLÜ teaduskeelekeskus korraldas koos TLÜ eesti keele ja kultuuri instituudiga 29. ja 30. augustil rahvusvahelise konverentsi "Rahvuskeeled teaduses ja kõrghariduses". Sel teemal vastavad TLÜ teaduskeelekeskuse juhataja Peep Nemvaltsi küsimustele konverentsi rahvusvahelised esinejad

  16. Basics of compounding: Tips and hints: powders, capsules, tablets, suppositories, and sticks, part 1.

    Science.gov (United States)

    Allen, Loyd V

    2014-01-01

    No matter the profession, professionals should never stop learning. This is especially true and important in the profession of compounding pharmacy. Compounding pharmacists are continuously faced with the challenge of finding new and inventive ways to assist patients with their individual and specific drug requirements. As compounding pharmacists learn, be it through formal continuing education or experience, they should be willing to share their knowledge with other compounders. In our goal of providing compounding pharmacists with additional knowledge to improve their skills in the art and practice of compounding, this article, which provides tips and hits on compounding with powders, capsules, tablets, suppositories, and sticks, represents the first in a series of articles to assist compounding pharmacists in the preparation of compounded medications.

  17. Design of sweet protein based sweeteners: hints from structure-function relationships.

    Science.gov (United States)

    Rega, Michele Fortunato; Di Monaco, Rossella; Leone, Serena; Donnarumma, Federica; Spadaccini, Roberta; Cavella, Silvana; Picone, Delia

    2015-04-15

    Sweet proteins represent a class of natural molecules, which are extremely interesting regarding their potential use as safe low-calories sweeteners for individuals who need to control sugar intake, such as obese or diabetic subjects. Punctual mutations of amino acid residues of MNEI, a single chain derivative of the natural sweet protein monellin, allow the modulation of its taste. In this study we present a structural and functional comparison between MNEI and a sweeter mutant Y65R, containing an extra positive charge on the protein surface, in conditions mimicking those of typical beverages. Y65R exhibits superior sweetness in all the experimental conditions tested, has a better solubility at mild acidic pH and preserves a significant thermal stability in a wide range of pH conditions, although slightly lower than MNEI. Our findings confirm the advantages of structure-guided protein engineering to design improved low-calorie sweeteners and excipients for food and pharmaceutical preparations. Copyright © 2014 Elsevier Ltd. All rights reserved.

  18. The infrared medium-deep survey. II. How to trigger radio AGNs? Hints from their environments

    Energy Technology Data Exchange (ETDEWEB)

    Karouzos, Marios; Im, Myungshin; Kim, Jae-Woo; Lee, Seong-Kook; Jeon, Yiseul; Choi, Changsu; Hong, Jueun; Hyun, Minhee; Jun, Hyunsung David; Kim, Dohyeong; Kim, Yongjung; Kim, Ji Hoon; Kim, Duho; Park, Won-Kee; Taak, Yoon Chan; Yoon, Yongmin [CEOU—Astronomy Program, Department of Physics and Astronomy, Seoul National University, Gwanak-gu, Seoul 151-742 (Korea, Republic of); Chapman, Scott [Department of Physics and Atmospheric Science, Dalhousie University, Halifax, Nova Scotia (Canada); Pak, Soojong [School of Space Research, Kyung Hee University, Yongin-si, Gyeonggi-do 446-701 (Korea, Republic of); Edge, Alastair, E-mail: mkarouzos@astro.snu.ac.kr [Department of Physics, University of Durham, South Road, Durham, DH1 3LE (United Kingdom)

    2014-12-10

    Activity at the centers of galaxies, during which the central supermassive black hole is accreting material, is nowadays accepted to be rather ubiquitous and most probably a phase of every galaxy's evolution. It has been suggested that galactic mergers and interactions may be the culprits behind the triggering of nuclear activity. We use near-infrared data from the new Infrared Medium-Deep Survey and the Deep eXtragalactic Survey of the VIMOS-SA22 field and radio data at 1.4 GHz from the FIRST survey and a deep Very Large Array survey to study the environments of radio active galactic nuclei (AGNs) over an area of ∼25 deg{sup 2} and down to a radio flux limit of 0.1 mJy and a J-band magnitude of 23 mag AB. Radio AGNs are predominantly found in environments similar to those of control galaxies at similar redshift, J-band magnitude, and (M{sub u} – M{sub r} ) rest-frame color. However, a subpopulation of radio AGNs is found in environments up to 100 times denser than their control sources. We thus preclude merging as the dominant triggering mechanism of radio AGNs. By fitting the broadband spectral energy distribution of radio AGNs in the least and most dense environments, we find that those in the least dense environments show higher radio-loudness, higher star formation efficiencies, and higher accretion rates, typical of the so-called high-excitation radio AGNs. These differences tend to disappear at z > 1. We interpret our results in terms of a different triggering mechanism for these sources that is driven by mass loss through winds of young stars created during the observed ongoing star formation.

  19. Hints for Small Disks around Very Low Mass Stars and Brown Dwarfs

    International Nuclear Information System (INIS)

    Hendler, Nathanial P.; Mulders, Gijs D.; Pascucci, Ilaria; Greenwood, Aaron; Kamp, Inga; Henning, Thomas; Ménard, François; Dent, William R. F.; II, Neal J. Evans

    2017-01-01

    The properties of disks around brown dwarfs and very low mass stars (hereafter VLMOs) provide important boundary conditions on the process of planet formation and inform us about the numbers and masses of planets than can form in this regime. We use the Herschel Space Observatory PACS spectrometer to measure the continuum and [O i] 63 μ m line emission toward 11 VLMOs with known disks in the Taurus and Chamaeleon I star-forming regions. We fit radiative transfer models to the spectral energy distributions of these sources. Additionally, we carry out a grid of radiative transfer models run in a regime that connects the luminosity of our sources with brighter T Tauri stars. We find that VLMO disks with sizes 1.3–78 au, smaller than typical T Tauri disks, fit well the spectral energy distributions assuming that disk geometry and dust properties are stellar mass independent. Reducing the disk size increases the disk temperature, and we show that VLMOs do not follow previously derived disk temperature–stellar luminosity relationships if the disk outer radius scales with stellar mass. Only 2 out of 11 sources are detected in [O i] despite a better sensitivity than was achieved for T Tauri stars, suggesting that VLMO disks are underluminous. Using thermochemical models, we show that smaller disks can lead to the unexpected [O i] 63 μ m nondetections in our sample. The disk outer radius is an important factor in determining the gas and dust observables. Hence, spatially resolved observations with ALMA—to establish if and how disk radii scale with stellar mass—should be pursued further.

  20. Tandem mass spectrometry of nitric oxide and hydrogen sulfide releasing aspirins: a hint into activity behavior.

    Science.gov (United States)

    Crestoni, Maria Elisa; Chiavarino, Barbara; Guglielmo, Stefano; Lilla, Valentina; Fornarini, Simonetta

    2013-01-01

    Aspirin (acetylsalicylic acid, ASA) is the most popular non-steroidal anti-inflammatory drug. However, due to its action on cyclooxygenase and its acid nature, aspirin is associated with adverse gastrointestinal effects. In an effort to minimize these side effects, NO-donor and H2S-donor ASA co-drugs have been designed and tested. Their mass spectrometric behavior is now analyzed and reported. Positive ions were obtained by electrospray ionization involving protonation or alkali metal attachment. Their dissociation processes have been studied by collision induced dissociation in a triple quadrupole instrument. High mass accuracy measurements have been recorded on a Fourier transform ion cyclotron resonance mass spectrometer. The protonated molecules dissociate by an exclusive or largely prevailing path leading to acetyloxy-substituted benzoyl cation, namely an ASA unit. The process is reminiscent of the enzymatic hydrolysis, releasing intact ASA to a large extent. Only at higher collision energy does the formal ketene loss disrupt the ASA moiety. The gas phase chemistry of protonated ASA-releasing drugs develops along elementary dissociation steps analogous to the reactive processes in complex biological environments. This notion may provide a tool for preliminary testing of new compounds.

  1. Riia Oja : "Ruumi lihtsusel on korrastav mõju mõtetele" / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Riia Oja (sünd. 1967) valgustusest kui miljöö loojast, materjalidest, eramu projekteerimisest. Riia Ojast, kes töötab 1991. aastast sisearhitektuuribüroos AS Stuudio Gadis. Ill.: R. Oja värv. portree

  2. Is the CMS e e j j excess a hint for light supersymmetry?

    Science.gov (United States)

    Krauss, Manuel E.; Porod, Werner

    2015-09-01

    We discuss the impact of additional two-body decays of the right-handed neutrino into a light charged Higgs state on the dilepton plus dijet cross sections from resonant W' production. We consider in particular a supersymmetric left-right symmetric model which predicts such a light charged Higgs boson. We demonstrate that the e e j j excess as measured by CMS can be explained best if the W' also has decay modes into Higgsino-like charginos and neutralinos with masses of a few hundred GeV. Provided that this excess is confirmed, the model predicts also one right-handed neutrino with a mass below 200 GeV as well as a doubly charged Higgs boson which should be discovered at the LHC in the near future.

  3. Building Models to Predict Hint-or-Attempt Actions of Students

    Science.gov (United States)

    Castro, Francisco Enrique Vicente; Adjei, Seth; Colombo, Tyler; Heffernan, Neil

    2015-01-01

    A great deal of research in educational data mining is geared towards predicting student performance. Bayesian Knowledge Tracing, Performance Factors Analysis, and the different variations of these have been introduced and have had some success at predicting student knowledge. It is worth noting, however, that very little has been done to…

  4. Search for Z′, vacuum (instability and hints of high-energy structures

    Directory of Open Access Journals (Sweden)

    Accomando Elena

    2016-01-01

    Full Text Available We study the high-energy behaviour of a class of anomaly-free abelian extensions of the Standard Model. We focus on the interplay among the phenomenological characterisation of the model and the use of precise renormalisation group methods. Using as boundary conditions regions of the parameter space at the verge of current LHC probe, interesting unification patterns emerge linked to thresholds belonging to a SO(10 grand unification theory (GUT. We stress how the evolution of the mixing between the two abelian factors may provide a valuable tool to address the candidate high-energy embedding. The emerging unification scenarios are then challenged to be perturbative and to allow for a stable vacuum.

  5. Looking at learning communities with the appropriate glasses: hints and ideas from network sciences

    Directory of Open Access Journals (Sweden)

    Fabio Nascimbeni

    2013-02-01

    Full Text Available 0 0 1 229 1263 USAL 10 2 1490 14.0 Normal 0 21 false false false ES JA X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin-top:0cm; mso-para-margin-right:0cm; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0cm; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:Calibri; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-ansi-language:ES; mso-fareast-language:EN-US;} The level of network thinking within education – intended as the capacity to look at learning systems and communities by focussing on the relations among the involved actors (primarily teachers and learners and not only on the actors characteristics – is growing, with different speeds depending on the educational sector, but not at the pace needed to keep up with the increasingly network nature of our societies. We claim that educational research and practices should increase their capacity to look at learning communities through appropriate “networking-sensitive” glasses, and get equipped with tools and methods – such as Social network Analysis - to properly understand and support these networks. The application of Social Network Analysis to education, especially in the case of distance learning, can allow understanding the patterns of interactions between teachers and learners, and can facilitate the consolidation of new approaches to understand collaboration mechanisms. The paper presents and discusses - from a learning viewpoint - a brief overview of the main theoretical and practical contributions coming from Social Network Analysis – such as the “random graphs”, the “small-worlds” or the “weak-ties” theories – together with some general properties and dynamics of networks, believing that mastering these dynamics is extremely important for educational researchers and practitioners, when it comes to understanding and supporting meaningful collaborative learning.

  6. 76 FR 22714 - Proposed Collection; Comment Request; Health Information National Trends Survey 4 (HINTS 4) (NCI)

    Science.gov (United States)

    2011-04-22

    ... questions with inquiries into the communication channels through which understanding is being obtained, and... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Proposed Collection; Comment... content of the survey will focus on understanding the degree to which members of the general population...

  7. Human airway epithelial cells investigated by atomic force microscopy: A hint to cystic fibrosis epithelial pathology

    Energy Technology Data Exchange (ETDEWEB)

    Lasalvia, Maria [Department of Clinical and Experimental Medicine, University of Foggia, Foggia (Italy); Istituto Nazionale di Fisica Nucleare, Sezione di Bari, Bari (Italy); Castellani, Stefano [Department of Medical and Surgical Sciences, University of Foggia, Foggia (Italy); D’Antonio, Palma [Department of Clinical and Experimental Medicine, University of Foggia, Foggia (Italy); Perna, Giuseppe [Department of Clinical and Experimental Medicine, University of Foggia, Foggia (Italy); Istituto Nazionale di Fisica Nucleare, Sezione di Bari, Bari (Italy); Carbone, Annalucia [Department of Medical and Surgical Sciences, University of Foggia, Foggia (Italy); Colia, Anna Laura; Maffione, Angela Bruna [Department of Clinical and Experimental Medicine, University of Foggia, Foggia (Italy); Capozzi, Vito [Department of Clinical and Experimental Medicine, University of Foggia, Foggia (Italy); Istituto Nazionale di Fisica Nucleare, Sezione di Bari, Bari (Italy); Conese, Massimo, E-mail: massimo.conese@unifg.it [Department of Medical and Surgical Sciences, University of Foggia, Foggia (Italy)

    2016-10-15

    The pathophysiology of cystic fibrosis (CF) airway disease stems from mutations in the CF Transmembrane Conductance Regulator (CFTR) gene, leading to a chronic respiratory disease. Actin cytoskeleton is disorganized in CF airway epithelial cells, likely contributing to the CF-associated basic defects, i.e. defective chloride secretion and sodium/fluid hypersorption. In this work, we aimed to find whether this alteration could be pointed out by means of Atomic Force Microscopy (AFM) investigation, as roughness and Young's elastic module. Moreover, we also sought to determine whether disorganization of actin cytoskeleton is linked to hypersoption of apical fluid. Not only CFBE41o- (CFBE) cells, immortalized airway epithelial cells homozygous for the F508del CFTR allele, showed a different morphology in comparison with 16HBE14o- (16HBE) epithelial cells, wild-type for CFTR, but also they displayed a lack of stress fibers, suggestive of a disorganized actin cytoskeleton. AFM measurements showed that CFBE cells presented a higher membrane roughness and decreased rigidity as compared with 16HBE cells. CFBE overexpressing wtCFTR became more elongated than the parental CFBE cell line and presented actin stress fibers. CFBE cells absorbed more fluid from the apical compartment. Study of fluid absorption with the F-actin-depolymerizing agent Latrunculin B demonstrated that actin cytoskeletal disorganization increased fluid absorption, an effect observed at higher magnitude in 16HBE than in CFBE cells. For the first time, we demonstrate that actin cytoskeleton disorganization is reflected by AFM parameters in CF airway epithelial cells. Our data also strongly suggest that the lack of stress fibers is involved in at least one of the early step in CF pathophysiology at the levels of the airways, i.e. fluid hypersorption. - Highlights: • CF bronchial epithelial (CFBE) cells show a disorganized actin cytoskeleton. • CFBE cells present high roughness and low rigidity in the plasmamembrane. • CFTR overexpression changes morphology and actin organization. • CFBE cells absorb more apical fluid than wild type bronchial epithelial cells. • Fluid absorption is increased by disorganization of actin cytoskeleton.

  8. Hints on the Nature of Dark Matter from the Properties of Milky Way Satellites

    NARCIS (Netherlands)

    Anderhalden, D.; Schneider, A.; Macciò, A.V.; Diemand, J.; Bertone, G.

    2013-01-01

    The nature of dark matter is still unknown and one of the most fundamental scientific mysteries. Although successfully describing large scales, the standard cold dark matter model (CDM) exhibits possible shortcomings on galactic and sub-galactic scales. It is exactly at these highly non-linear

  9. Ultra high energy cosmic rays above 10 GeV: Hints to new physics ...

    Indian Academy of Sciences (India)

    Ultra high energy cosmic rays; physics beyond standard model. ... The origin of the observed cosmic ray (CR) events above 10ѕј eV — the so-called ex- .... to arise simply from decay of some supermassive particles (of mass> 10ѕЅ eV) ...

  10. Immunotherapeutic Potential of Oncolytic H-1 Parvovirus: Hints of Glioblastoma Microenvironment Conversion towards Immunogenicity.

    Science.gov (United States)

    Angelova, Assia L; Barf, Milena; Geletneky, Karsten; Unterberg, Andreas; Rommelaere, Jean

    2017-12-15

    Glioblastoma, one of the most aggressive primary brain tumors, is characterized by highly immunosuppressive microenvironment. This contributes to glioblastoma resistance to standard treatment modalities and allows tumor growth and recurrence. Several immune-targeted approaches have been recently developed and are currently under preclinical and clinical investigation. Oncolytic viruses, including the autonomous protoparvovirus H-1 (H-1PV), show great promise as novel immunotherapeutic tools. In a first phase I/IIa clinical trial (ParvOryx01), H-1PV was safe and well tolerated when locally or systemically administered to recurrent glioblastoma patients. The virus was able to cross the blood-brain (tumor) barrier after intravenous infusion. Importantly, H-1PV treatment of glioblastoma patients was associated with immunogenic changes in the tumor microenvironment. Tumor infiltration with activated cytotoxic T cells, induction of cathepsin B and inducible nitric oxide (NO) synthase (iNOS) expression in tumor-associated microglia/macrophages (TAM), and accumulation of activated TAM in cluster of differentiation (CD) 40 ligand (CD40L)-positive glioblastoma regions was detected. These are the first-in-human observations of H-1PV capacity to switch the immunosuppressed tumor microenvironment towards immunogenicity. Based on this pilot study, we present a tentative model of H-1PV-mediated modulation of glioblastoma microenvironment and propose a combinatorial therapeutic approach taking advantage of H-1PV-induced microglia/macrophage activation for further (pre)clinical testing.

  11. Taso Mähar : maali ümber ehitatud maja / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    220-ruutmeetrise ühekorde eramu sisekujundus. Arhitekt Emil Urbel. Sisearhitekt Taso Mähar, tema kommentaarid. Köögimööbel on T. Mähari projekteeritud. Elutoas mööblifirma T&T Mang pehme mööbel, seinal Lemming Nageli maal "Punane joon all - Burn Out". Ill.: plaan, 17 värv. vaadet

  12. Understanding Public Engagement in Water Conservation Behaviors and Knowledge of Water Policy: Promising Hints for Extension

    Science.gov (United States)

    Huang, Pei-wen; Lamm, Alexa J.

    2015-01-01

    Sustaining water resources is a primary issue facing Florida Extension. The study reported here identified how experience with water issues and familiarity with water policies affected individuals' engagement in water conservation behaviors. A public opinion survey was conducted online to capture Florida residents' responses. The findings…

  13. Melatonin, Noncoding RNAs, Messenger RNA Stability and Epigenetics—Evidence, Hints, Gaps and Perspectives

    Directory of Open Access Journals (Sweden)

    Rüdiger Hardeland

    2014-10-01

    Full Text Available Melatonin is a highly pleiotropic regulator molecule, which influences numerous functions in almost every organ and, thus, up- or down-regulates many genes, frequently in a circadian manner. Our understanding of the mechanisms controlling gene expression is actually now expanding to a previously unforeseen extent. In addition to classic actions of transcription factors, gene expression is induced, suppressed or modulated by a number of RNAs and proteins, such as miRNAs, lncRNAs, piRNAs, antisense transcripts, deadenylases, DNA methyltransferases, histone methylation complexes, histone demethylases, histone acetyltransferases and histone deacetylases. Direct or indirect evidence for involvement of melatonin in this network of players has originated in different fields, including studies on central and peripheral circadian oscillators, shift work, cancer, inflammation, oxidative stress, aging, energy expenditure/obesity, diabetes type 2, neuropsychiatric disorders, and neurogenesis. Some of the novel modulators have also been shown to participate in the control of melatonin biosynthesis and melatonin receptor expression. Future work will need to augment the body of evidence on direct epigenetic actions of melatonin and to systematically investigate its role within the network of oscillating epigenetic factors. Moreover, it will be necessary to discriminate between effects observed under conditions of well-operating and deregulated circadian clocks, and to explore the possibilities of correcting epigenetic malprogramming by melatonin.

  14. HEALTH INFO SANTE ANNUAL DEDUCTIBLE AND REIMBURSEMENT CLAIMS: HINTS FOR USE

    CERN Multimedia

    1999-01-01

    Information from the CHIS Board and the Personnel DivisionOne should bear in mind that the annual deductible is an amount (currently CHF 100) charged automatically by the Administrator of the scheme for every adult aged 18 and above. This is what happens: The amount is deducted annually for all medical services received over a calendar year.It is triggered by the date of the treatment and not by the date of the bill nor that of the reimbursement claim.In other words, if you receive medical treatment in December for the first time in a given year, the CHF 100 will be deducted from the claim for that treatment. So, except for urgent cases, it would be better to wait till the following month, thus avoiding one annual deductible.It is also worth remembering that the cost of processing our reimbursement claims - and there were 55, 000 in 1998 - is part of the cost of our insurance.Help keep administrative costs down : do not submit reimbursement claims for amounts less than the annual deductible unless your claims...

  15. An overview of MR arthrography with emphasis on the current technique and applicational hints and tips

    International Nuclear Information System (INIS)

    Sahin, Guelden; Demirtas, Mehmet

    2006-01-01

    Magnetic resonance (MR) arthrography has been investigated in every major peripheral joint of the body, and has been proven to be effective in determining the integrity of intraarticular ligamentous and fibrocartilaginous structures and in the detection or assessment of osteochondral lesions and loose bodies in selected cases. Several methods could be used to create arthrogram effect during MR imaging, however, direct MR arthrography using diluted gadolinium as the contrast agent is the most commonly used technique and is the most reliable of all. MR arthrography is useful for demonstrating labrocapsular-ligamentous abnormalities and distinguishing partial thickness rotator cuff tears from focal full thickness tears in the shoulder, identifying or excluding recurrent tears following meniscal operations in the knee, demonstrating perforations of the triangular fibrocartilage complex (TFCC) and ligaments in the wrist, showing labral tears in the hip, diagnosing ligament tears in the ankle and identifying osteochondral lesions or loose bodies in any of the aforementioned joints. In this article, an overview of techniques of MR arthrography is provided with emphasis on direct MR arthrography using diluted gadolinium as the contrast agent. The current applications of the technique in major peripheral joints are reviewed, with emphasis given to the shoulder joint where the role of this technique has become well established

  16. IceCube events and decaying dark matter: hints and constraints

    Science.gov (United States)

    Esmaili, Arman; Kang, Sin Kyu; Dario Serpico, Pasquale

    2014-12-01

    In the light of the new IceCube data on the (yet unidentified) astrophysical neutrino flux in the PeV and sub-PeV range, we present an update on the status of decaying dark matter interpretation of the events. In particular, we develop further the angular distribution analysis and discuss the perspectives for diagnostics. By performing various statistical tests (maximum likelihood, Kolmogorov-Smirnov and Anderson-Darling tests) we conclude that currently the data show a mild preference (below the two sigma level) for the angular distribution expected from dark matter decay vs. the isotropic distribution foreseen for a conventional astrophysical flux of extragalactic origin. Also, we briefly develop some general considerations on heavy dark matter model building and on the compatibility of the expected energy spectrum of decay products with the IceCube data, as well as with existing bounds from gamma-rays. Alternatively, assuming that the IceCube data originate from conventional astrophysical sources, we derive bounds on both decaying and annihilating dark matter for various final states. The lower limits on heavy dark matter lifetime improve by up to an order of magnitude with respect to existing constraints, definitively making these events—even if astrophysical in origin—an important tool for astroparticle physics studies.

  17. IceCube events and decaying dark matter: hints and constraints

    International Nuclear Information System (INIS)

    Esmaili, Arman; Kang, Sin Kyu; Serpico, Pasquale Dario

    2014-01-01

    In the light of the new IceCube data on the (yet unidentified) astrophysical neutrino flux in the PeV and sub-PeV range, we present an update on the status of decaying dark matter interpretation of the events. In particular, we develop further the angular distribution analysis and discuss the perspectives for diagnostics. By performing various statistical tests (maximum likelihood, Kolmogorov-Smirnov and Anderson-Darling tests) we conclude that currently the data show a mild preference (below the two sigma level) for the angular distribution expected from dark matter decay vs. the isotropic distribution foreseen for a conventional astrophysical flux of extragalactic origin. Also, we briefly develop some general considerations on heavy dark matter model building and on the compatibility of the expected energy spectrum of decay products with the IceCube data, as well as with existing bounds from gamma-rays. Alternatively, assuming that the IceCube data originate from conventional astrophysical sources, we derive bounds on both decaying and annihilating dark matter for various final states. The lower limits on heavy dark matter lifetime improve by up to an order of magnitude with respect to existing constraints, definitively making these events—even if astrophysical in origin—an important tool for astroparticle physics studies

  18. What concentration of actinides can be packed into calcite? Hints from rare earth element (REE) composition

    International Nuclear Information System (INIS)

    Christiansen, J.; Stipp, S.L.S.; Waight, T.; Baker, J.A.

    2005-01-01

    Full text of publication follows: For reliable modelling of actinide mobility in the event of spent fuel repository failure, we need data describing the uptake capacity of the minerals likely to find themselves in the transport path. Calcite (CaCO 3 ) is a common secondary mineral in fractures and pore fillings, especially downstream from degrading concrete facilities, so it is a likely candidate for incorporation. Investigations made under ACTAF, a 5. Framework EURATOM integrated project, as well as some other research studies, have shown that actinides are successfully incorporated as substituting ions within the calcite mineral structure. The question remaining, is how much can calcite take up. Geologists routinely use relative concentrations of rare Earth elements (REE's), the lanthanides, for interpreting rock genesis and history. One can also adopt them as analogues for the radioactive elements because their f-orbital electron configuration makes them behave very much like actinides. We collected and analysed a suite of 70 calcite samples from a great number of possible formation environments, geological ages and geographical locations, for the purpose of finding the range and maximum of total f-orbital substitution possible in calcite, under natural conditions. We analysed them using Multi-Collector Inductively Coupled Plasma Mass Spectrometry (MC-ICP-MS). The maximum concentration found was about 5 x 10 -3 mole/kg total REE in a sample that had a geological history of formation where REE fluids played a role. Over the whole suite, total REE ranged from less than 10 -4 moles/kg for limestone samples formed from biogenic calcite where REE-enriched fluids would have played a negligible role. Thus, in natural calcite, REE's are present and all evidence points to a structural incorporation within the mineral rather than as a separate REE-rich phase. These data compare favourably with mole fractions from calcite grown synthetically, where as much as 6 x 10 -3 moles Eu were incorporated per kg calcite. These results give confidence that if the concentrations are low and calcite formation is favoured, migrating actinides will be incorporated into calcite, to be immobilised there, as long as solution conditions do not favour its dissolution. (authors)

  19. Supportive hints in a digital learning environment : Effects on students' motivation

    NARCIS (Netherlands)

    ter Beek, Marlies; Brummer, Leonie; Donker-Bergstra, Anouk; Opdenakker, Marie-christine

    2017-01-01

    Reading skills are developed across the lifespan. However, little is known about the development of reading comprehension skills and materials in secondary education, where students do not learn to read, but read to learn. When students read informational textbooks, domain knowledge (e.g., about

  20. The close of the year brings a hint that prices may be coming down

    International Nuclear Information System (INIS)

    Anon.

    1997-01-01

    A summary of financial data for the uranium spot market in December 1996 is provided. Price ranges for the restricted and unrestricted markets, conversion, and separative work are listed, and total market volume and new contracts are noted. Transactions made are briefly described. Deals made and pending in the spot concentrates, medium and long-term, conversion, and markets are listed for U.S. and non-U.S. buyers

  1. Electric field fluctuations in liquid tellurium alloys a hint to bond character

    NARCIS (Netherlands)

    Paulick, C.A.; Brinkmann, R.; Elwenspoek, Michael Curt; von Hartrott, M.; Kiehl, M.; Maxim, P.; Quitmann, D.

    1985-01-01

    Atomic scale electric field fluctuations in liquid tellurium alloys are detected as they induce nuclear spin relaxation rate RQ in noble gas impurity atoms, via quadrupolar interaction. Results for Xe in liquid Ag, Ga, In, Tl, Ge, Sn---Te alloys are discussed, assuming that bonding in these alloys

  2. Smartphone Ownership Among US Adult Cigarette Smokers: 2014 Health Information National Trends Survey (HINTS) Data

    OpenAIRE

    Heffner, Jaimee L; Mull, Kristin E

    2017-01-01

    Background Despite increasing interest in smartphone apps as a platform for delivery of tobacco cessation interventions, no previous studies have evaluated the prevalence and characteristics of smokers who can access smartphone-delivered interventions. Objective To guide treatment development in this new platform and to evaluate disparities in access to smartphone-delivered interventions, we examined associations of smartphone ownership with demographics, tobacco use and thoughts about quitti...

  3. Cutaneous melanoma: hints from occupational risks by anatomic site in Swedish men

    Science.gov (United States)

    Perez-Gomez, B; Pollan, M; Gustavsson, P; Plato, N; Aragones, N; Lopez-Abente, G

    2004-01-01

    Aims: To improve knowledge of the epidemiology of melanoma by comparing occupational risks of cutaneous melanoma (CM) by anatomic site in Swedish workers. Methods: Male workers employed in 1970 and living in the country in 1960 were followed up from 1971 to 1989 using the Swedish Registers of Death and Cancer. A more specifically exposed subcohort included men reporting the same occupation in 1960 and 1970. For each location, occupational risk ratios (RRs) were extracted from Poisson regression models adjusted by age, period, town size, and geographical area. To diminish the influence of socioeconomic factors, intrasector analyses, comparing only jobs belonging to the same occupational sector, were performed. Risk patterns for different locations were compared. Results: High RRs for different sites were found among workers exposed to UV sources (dentists, physiotherapists, and lithographers), and sun exposed workers (harbour masters, and lighthouse/related work). Risk excesses were seen in fur tailors, tanners/fur dressers, patternmakers/cutters, electrical fitters/wiremen, telephone/telegraph installers/repairmen, and some glass/pottery/tile workers. Results for lower and upper limbs were significantly correlated but somewhat independent of those found in thorax, the most frequent location. Correlation between head/neck and thorax was moderate. Specific risk excesses were found for rolling mill workers in head/neck, for chimney sweeps in upper limbs, and for aircraft pilots/navigators/flight engineers in lower limbs. Conclusions: High RRs in the trunk among occupations with UV exposure from artificial sources suggest an effect not restricted to exposed sites. An unusual distribution of cases and RRs in chimney sweeps, rolling-mill, or glass/pottery/tile workers suggests local effects of exposures. The not previously reported risk excess in this job and in fur related processes, and the RR in electrical fitters and telephone/telegraph installers deserve further investigation. Disparities between locations, as RRs in thorax and limbs, may reflect differences in aetiological mechanisms. PMID:14739377

  4. Sünnitades "Ema ja tütart" / Anna Hints

    Index Scriptorium Estoniae

    Hints, Anna, 1982-

    2010-01-01

    Tartu sünnitusmajale Toomemäel, naise eluringile ja põlvkondade järjepidevusele pühendatud "Ema ja tütar" kui koha, heli, foto ja rituaalse tegevuse koostoimel sündinud autori tajuvõrgustikku dekodeeriv pärimusliku ja isikliku taustaga kunstitöö

  5. Bulk Comptonization: new hints from the luminous blazar 4C+25.05

    Science.gov (United States)

    Kammoun, E. S.; Nardini, E.; Risaliti, G.; Ghisellini, G.; Behar, E.; Celotti, A.

    2018-01-01

    Blazars are often characterized by a spectral break at soft X-rays, whose origin is still debated. While most sources show a flattening, some exhibit a blackbody-like soft excess with temperatures of the order of ∼0.1 keV, similar to low-luminosity, non-jetted Seyferts. Here, we present the analysis of the simultaneous XMM-Newton and NuSTAR observations of the luminous flat-spectrum radio quasar 4C+25.05 (z = 2.368). The observed 0.3-30 keV spectrum is best described by the sum of a hard X-ray power law (Γ = 1.38_{-0.03}^{+0.05}) and a soft component, approximated by a blackbody with kT_BB = 0.66_{-0.04}^{+0.05} keV (rest frame). If the spectrum of 4C+25.05 is interpreted in the context of bulk Comptonization by cold electrons of broad-line region photons emitted in the direction of the jet, such an unusual temperature implies a bulk Lorentz factor of the jet of Γbulk ∼ 11.7. Bulk Comptonization is expected to be ubiquitous on physical grounds, yet no clear signature of it has been found so far, possibly due to its transient nature and the lack of high-quality, broad-band X-ray spectra.

  6. Heterogeneous rates for birth defects in Latin America: hints on causality.

    Science.gov (United States)

    Lopez-Camelo, J S; Orioli, I M

    1996-01-01

    The aim of this work was to disclose risk factors associated with birth defects which were heterogeneously distributed in the different geographic regions sampled by the Latin American Collaborative Study of Congenital Malformations (ECLAMC). The material included 2,159,065 hospital births, delivered in the 1967-1989 period in 24 geographic regions of Latin America. Birth defect types with 50 case-control pairs or more were analyzed. A risk factor was defined as that available variable with differential geographic rates, correlated with those of a given birth defect type. Identified factors were tested by case-control multivariate logistic regression to confirm their role in the occurrence of the defect. Altitude and maternal acute illness during first trimester of pregnancy, named influenza, were risk factors for microtia. Prenatal drug exposure, mainly sex hormones, were connected with the occurrence of hypospadias in low frequency areas, while Native ancestry was a "protective" factor in the same regions. Acute (influenza), and chronic (epilepsy and syphilis) maternal illness during first trimester of pregnancy and gravidity higher than four were risk factors for cleft lip. The independence of these variables from maternal age suggested that low maternal socioeconomic level could explain the high birth defect order and, perhaps, syphilis in mothers. Postaxial polydactyly was associated with parental consanguinity, as well as Afro-American ancestry, suggesting genetic heterogeneity.

  7. On a Fairy's Wing: Hints of Fitzgerald in Hemingway's "The Butterfly and the Tank"

    OpenAIRE

    Plath, James

    2008-01-01

    Lorsque, encore en France, Ernest Hemingway compose « The Butterfly and the Tank », le souvenir de conduite outrancière des Fitzgerald à Paris et à Juan-les-Pins est certainement présent dans son esprit. Le nombre d’allusions à Scott et Zelda sont trop soulignées pour qu’il en soit autrement. La structure de cette nouvelle, avec un Hemingway qui tient le rôle habituel de correspondant aguerri confirme ce postulat.Hemingway s’est souvent montré critique par rapport aux lamentations de Fitzgera...

  8. Õun. Minu kõige mõttetum ost : [jutt] / Anna Hints

    Index Scriptorium Estoniae

    Hints, Anna

    2006-01-01

    Sisu: Juuli 2004 ; August 2004 ; September 2004 ; September 2004, kuskil keskel ; September 2004, lõpus ; Oktoober 2004, 1. nädal ; Oktoober 2004, 2. nädal ; Oktoober 2004, 3. nädala alguses ; Oktoober 2004, 3. nädala lõpupoole ; Oktoober 2004, 4. nädal ; November 2004, 1. nädal ; November 2004, lõpp ; Jaanuar 2005, täna

  9. SPINS OF LARGE ASTEROIDS: A HINT OF A PRIMORDIAL DISTRIBUTION IN THEIR SPIN RATES

    Energy Technology Data Exchange (ETDEWEB)

    Steinberg, Elad; Sari, Re’em [The Hebrew University of Jerusalem, Jerusalem (Israel)

    2015-04-15

    The Asteroid Belt and the Kuiper Belt are relics from the formation of our solar system. Understanding the size and spin distribution of the two belts is crucial for a deeper understanding of the formation of our solar system and the dynamical processes that govern it. In this paper, we investigate the effect of collisions on the evolution of the spin distribution of asteroids and KBOs. We find that the power law nature of the impactors’ size distribution leads to a Lévy distribution of the spin rates. This results in a power law tail in the spin distribution, in stark contrast to the usually quoted Maxwellian distribution. We show that for bodies larger than 10 km, collisions alone lead to spin rates peaking at 0.15–0.5 revolutions per day. Comparing that to the observed spin rates of large asteroids (R > 50 km), we find that the spins of large asteroids, peaking at ∼1–2 revolutions per day, are dominated by a primordial component that reflects the formation mechanism of the asteroids. Similarly, the Kuiper Belt has undergone virtually no collisional spin evolution, assuming current densities. Collisions contribute a spin rate of ∼0.01 revolutions per day, thus the observed fast spin rates of KBOs are also primordial in nature.

  10. Hints for Small Disks around Very Low Mass Stars and Brown Dwarfs

    Energy Technology Data Exchange (ETDEWEB)

    Hendler, Nathanial P.; Mulders, Gijs D.; Pascucci, Ilaria [Lunar and Planetary Laboratory, The University of Arizona, Tucson, AZ 85721 (United States); Greenwood, Aaron; Kamp, Inga [Kapteyn Astronomical Institute, University of Groningen, Postbus 800, 9700 AV Groningen (Netherlands); Henning, Thomas [Max Planck Institute for Astronomy, Konigstuhl 17, D-69117 Heidelberg (Germany); Ménard, François [Univ. Grenoble Alpes, CNRS, IPAG, F-38000 Grenoble (France); Dent, William R. F. [Department of Engineering, Atacama Large Millimeter/submillimeter Array (ALMA) Santiago Central Offices, Alonso de Córdova 3107, Vitacura, Casilla 763 0355, Santiago (Chile); II, Neal J. Evans, E-mail: equant@lpl.arizona.edu [Department of Astronomy, The University of Texas at Austin, Austin, TX 78712 (United States)

    2017-06-01

    The properties of disks around brown dwarfs and very low mass stars (hereafter VLMOs) provide important boundary conditions on the process of planet formation and inform us about the numbers and masses of planets than can form in this regime. We use the Herschel Space Observatory PACS spectrometer to measure the continuum and [O i] 63 μ m line emission toward 11 VLMOs with known disks in the Taurus and Chamaeleon I star-forming regions. We fit radiative transfer models to the spectral energy distributions of these sources. Additionally, we carry out a grid of radiative transfer models run in a regime that connects the luminosity of our sources with brighter T Tauri stars. We find that VLMO disks with sizes 1.3–78 au, smaller than typical T Tauri disks, fit well the spectral energy distributions assuming that disk geometry and dust properties are stellar mass independent. Reducing the disk size increases the disk temperature, and we show that VLMOs do not follow previously derived disk temperature–stellar luminosity relationships if the disk outer radius scales with stellar mass. Only 2 out of 11 sources are detected in [O i] despite a better sensitivity than was achieved for T Tauri stars, suggesting that VLMO disks are underluminous. Using thermochemical models, we show that smaller disks can lead to the unexpected [O i] 63 μ m nondetections in our sample. The disk outer radius is an important factor in determining the gas and dust observables. Hence, spatially resolved observations with ALMA—to establish if and how disk radii scale with stellar mass—should be pursued further.

  11. Renewable energy technologies. Plant concepts, applications and practical hints; Regenerative Energietechnologien. Anlagenkonzepte, Anwendungen und Praxistipps

    Energy Technology Data Exchange (ETDEWEB)

    Theiss, Eric

    2008-07-01

    This textbook provides a comprehensive outline of renewable energy technologies, prototypes and innovations in technical facilities that are ready for the market. On the basis of current catalogues of technical rules, directives and guidelines, possible system configurations are outlined for each technology which are explained by means of examples, a system description, and a list of reference projects. There is also a glossary for the various technologies and a list of contact addresses. The textbook addresses architects, engineers, energy consultants, and students. (orig.)

  12. Hints of hybridizing Majorana fermions in a nanowire coupled to superconducting leads

    Science.gov (United States)

    Finck, A. D. K.; van Harlingen, D. J.; Mohseni, P. K.; Jung, K.; Li, X.

    2013-03-01

    It has been proposed that a nanowire with strong spin-orbit coupling that is contacted with a conventional superconductor and subjected to a large magnetic field can be driven through a topological phase transition. In this regime, the two ends of the nanowire together host a pair of quasi-particles known as Majorana fermions (MFs). A key feature of MFs is that they are pinned to zero energy when the topological nanowire is long enough such that the wave functions of the two MFs do not overlap significantly, resulting in a zero bias anomaly (ZBA). It has been recently predicted that changes in external parameters can vary the wave function overlap and cause the MFs to hybridize in an oscillatory fashion. This would lead to a non-monotonic splitting or broadening of the ZBA and help distinguish MF transport signatures from a Kondo effect. Here, we present transport studies of an InAs nanowire contacted with niobium nitride leads in high magnetic fields. We observe a number of robust ZBAs that can persist for a wide range of back gate bias and magnetic field strength. Under certain conditions, we find that the height and width of the ZBA can oscillate with back gate bias or magnetic field. This work was supported by Microsoft Project Q.

  13. Association of tinnitus and electromagnetic hypersensitivity: hints for a shared pathophysiology?

    Directory of Open Access Journals (Sweden)

    Michael Landgrebe

    Full Text Available BACKGROUND: Tinnitus is a frequent condition with high morbidity and impairment in quality of life. The pathophysiology is still incompletely understood. Electromagnetic fields are discussed to be involved in the multi-factorial pathogenesis of tinnitus, but data proofing this relationship are very limited. Potential health hazards of electromagnetic fields (EMF have been under discussion for long. Especially, individuals claiming themselves to be electromagnetic hypersensitive suffer from a variety of unspecific symptoms, which they attribute to EMF-exposure. The aim of the study was to elucidate the relationship between EMF-exposure, electromagnetic hypersensitivity and tinnitus using a case-control design. METHODOLOGY: Tinnitus occurrence and tinnitus severity were assessed by questionnaires in 89 electromagnetic hypersensitive patients and 107 controls matched for age-, gender, living surroundings and workplace. Using a logistic regression approach, potential risk factors for the development of tinnitus were evaluated. FINDINGS: Tinnitus was significantly more frequent in the electromagnetic hypersensitive group (50.72% vs. 17.5% whereas tinnitus duration and severity did not differ between groups. Electromagnetic hypersensitivity and tinnitus were independent risk factors for sleep disturbances. However, measures of individual EMF-exposure like e.g. cell phone use did not show any association with tinnitus. CONCLUSIONS: Our data indicate that tinnitus is associated with subjective electromagnetic hypersensitivity. An individual vulnerability probably due to an over activated cortical distress network seems to be responsible for, both, electromagnetic hypersensitivity and tinnitus. Hence, therapeutic efforts should focus on treatment strategies (e.g. cognitive behavioral therapy aiming at normalizing this dysfunctional distress network.

  14. Origin and evolution of retinoid isomerization machinery in vertebrate visual cycle: hint from jawless vertebrates.

    Science.gov (United States)

    Poliakov, Eugenia; Gubin, Alexander N; Stearn, Olivia; Li, Yan; Campos, Maria Mercedes; Gentleman, Susan; Rogozin, Igor B; Redmond, T Michael

    2012-01-01

    In order to maintain visual sensitivity at all light levels, the vertebrate eye possesses a mechanism to regenerate the visual pigment chromophore 11-cis retinal in the dark enzymatically, unlike in all other taxa, which rely on photoisomerization. This mechanism is termed the visual cycle and is localized to the retinal pigment epithelium (RPE), a support layer of the neural retina. Speculation has long revolved around whether more primitive chordates, such as tunicates and cephalochordates, anticipated this feature. The two key enzymes of the visual cycle are RPE65, the visual cycle all-trans retinyl ester isomerohydrolase, and lecithin:retinol acyltransferase (LRAT), which generates RPE65's substrate. We hypothesized that the origin of the vertebrate visual cycle is directly connected to an ancestral carotenoid oxygenase acquiring a new retinyl ester isomerohydrolase function. Our phylogenetic analyses of the RPE65/BCMO and N1pC/P60 (LRAT) superfamilies show that neither RPE65 nor LRAT orthologs occur in tunicates (Ciona) or cephalochordates (Branchiostoma), but occur in Petromyzon marinus (Sea Lamprey), a jawless vertebrate. The closest homologs to RPE65 in Ciona and Branchiostoma lacked predicted functionally diverged residues found in all authentic RPE65s, but lamprey RPE65 contained all of them. We cloned RPE65 and LRATb cDNAs from lamprey RPE and demonstrated appropriate enzymatic activities. We show that Ciona ß-carotene monooxygenase a (BCMOa) (previously annotated as an RPE65) has carotenoid oxygenase cleavage activity but not RPE65 activity. We verified the presence of RPE65 in lamprey RPE by immunofluorescence microscopy, immunoblot and mass spectrometry. On the basis of these data we conclude that the crucial transition from the typical carotenoid double bond cleavage functionality (BCMO) to the isomerohydrolase functionality (RPE65), coupled with the origin of LRAT, occurred subsequent to divergence of the more primitive chordates (tunicates, etc.) in the last common ancestor of the jawless and jawed vertebrates.

  15. Johannes Hint : ühe XX sajandi ausa mehe tragöödia / Holger Kaljulaid

    Index Scriptorium Estoniae

    Kaljulaid, Holger

    2006-01-01

    Desintegraatori juhi Johannes Hindi tegevusest ning temaga seotud kohtuprotsessist meedias avaldatud materjalide ja arhiividokumentide põhjal. Vt. samas väljavõtteid: Vladimir Georg Karassev-Orgusaare mõtteavaldusest 1982. aasta jaanuaris RL-i stuudios Pariisis; Johhannes Hindi sõnavõtust NSV Liidu Riikliku Plaanikomitee (Gosplan) kolleegiumil 10. II 1981 ja tema tööst "Viimaseid mõtteid inimkonnale", 1985; Aleksander Kaelase mõtteavaldusest aprillis 1955 Ameerika Hääle saates; Nikolai Baibakovi, Gosplani kunagise juhi (1965-85) 2000. a. märtsis antud intervjuust

  16. A 3.55 keV hint for decaying axion-like particle dark matter

    Energy Technology Data Exchange (ETDEWEB)

    Jaeckel, Joerg [Heidelberg Univ. (Germany). Inst. fuer Theoretische Physik; Redondo, Javier [Muenchen Univ. (Germany). Arnold Sommerfeld Center; Max-Planck-Institut fuer Physik, Muenchen (Germany); Ringwald, Andreas [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2014-02-15

    Recently, indications for an emission line at 3.55 keV have been found in the combined spectra of a large number of galaxy clusters and also in Andromeda. This line could not be identified with any known spectral line. It is tempting to speculate that it has its origin in the decay of a particle contributing all or part of the dark matter. In this note we want to point out that axion-like particles being all or part of the dark matter are an ideal candidate to produce such a feature. More importantly the parameter values necessary are quite feasible in extensions of the Standard Model based on string theory and could be linked up to a variety of other intriguing phenomena, which also potentially allow for new tests of this speculation.

  17. Are You a Gut Responder? Hints on Coping with an Irritable Bowel

    Science.gov (United States)

    ... problems to contend with. These can interfere with work or school and social functions both in obvious and subtle ways – including ... a better understanding of your own gut-brain connections, ask your doctor to suggest a mental health ... Read More Personal Relationships ...

  18. Hints about Dark, Light-Bending Matter in the Distant Universe

    Science.gov (United States)

    1997-07-01

    New infrared observations of a gravitational lens About 20 cases of gravitationally lensed (GL) quasars are known. This special physical effect, also known as a cosmic mirage, occurs when the rays of light of a distant quasar on their way to us pass near a massive object, for instance a galaxy. As a result, two or more images of the same quasar will be seen near each other. This phenomenon is described in more detail in the Appendix. A new study by a group of three European astronomers, headed by Frederic Courbin ( Institut d'Astrophysique, Universite de Liege, Belgium, and Observatoire de Paris-Meudon, France) [1], has led to the discovery of the object responsible for the double images of a remote quasar in the gravitational lens HE 1104-1805 . The investigation is based on infrared observations at the ESO La Silla Observatory in Chile and the `lensing system' turns out to be a distant, massive galaxy. Nevertheless, the geometry of the object is unusual and an additional gravitational lens of `dark' (invisible) matter may possibly be involved. This gravitational lens is also particularly well suited for future cosmological studies that aim at the determination of the Hubble constant and the expansion rate of the Universe. A new and detailed study of gravitational lenses It is rare among the relatively few, confirmed cases of gravitational lensing in the distant Universe, that the distribution of matter in the lensing system is well known. However, it is exactly this information that is needed to derive cosmological parameters by means of photometric monitoring of the brightness of the individual images in a gravitational lens [2]. The three astronomers have therefore undertaken a detailed study of some previously known gravitational lenses (or good candidate objects) with the primary aim to detect and map the associated lensing matter (refered to as the gravitational deflector or lensing object ). This is observationally quite difficult and time-consuming since the huge masses responsible for the gravitational bending of light are almost always located at very large distances from us. Thus they are quite faint and can only be observed with large telescopes and state-of-the-art equipment. Moreover, the faint images of lensing objects are located between the much brighter quasar images they lens. This makes the discovery of a lensing object and the recording of its image a most challenging task. The advantage of infrared observations The image of a remote galaxy is usually very faint at visible wavelengths, but it is brighter in the infra-red part of the spectrum. This is because the wavelength of maximum intensity in the spectrum of a rapidly receding, distant galaxy (a composite of the spectra of the stars of which it consists) is redshifted from the visual into the infrared region of the spectrum. For instance, galaxies with redshifts around z = 1 [3] are best observed in the J -band near the near-infrared wavelength of 1.25 microns (about twice that of red light), while the images of galaxies with even higher redshifts and velocities are better recorded in the 2.2 micron K -band. The present search for gravitational deflectors is therefore conducted in the infrared spectral region, using the ESO/MPI 2.2-m telescope and the IR detector IRAC 2b . Such a survey has the further advantage of revealing, if present, additional lensed images of the quasars, that may be heavily obscured by intervening dust, for example by the dust contained in the lensing galaxy. A new and powerful image combination/deconvolution algorithm These investigations have always been difficult because of the small angular separations in such lensed objects, of the order of one arcsecond, or even less in many cases. This corresponds to the image-smearing (seeing) effects introduced by atmospheric turbulence under common ground-based observing conditions. Detailed observations of such objects are therefore normally best made from space-based observatories, like the Hubble Space Telescope (HST). However, an alternative method of obtaining high-resolution images is to combine numerous exposures of the same object in an optimised way; this allows to `eliminate' most of the image degradation caused by atmospheric effects. New and powerful software for this procedure has recently been developed at the Astrophysical Institute in Liege, cf. http://vela.astro.ulg.ac.be/imaproc. The new algorithm allows to treat (`deconvolve') simultaneously a large number of exposures - especially in the infrared - and yields high-resolution, combined images of the celestial objects on which precise brightness and positional measurements can be performed. Detection of the lensing galaxy in HE 1104-1805 During the present programme, the astronomers recently observed HE 1104-1805 , a gravitational lens with a doubly imaged quasar with a redshift of z = 2.316 that was discovered in 1993 at the La Silla Observatory. Observations in 1995, made in the I -waveband (0.9 micron) under poor seeing conditions, showed a very faint feature between the quasar images but the observations did not allow to ascertain the nature of this object. Caption to ESO PR Photo 21/97 [JPEG, 55k] New infrared images were obtained during the night of April 14-15, 1997. They were then processed with the new software and the resulting, detailed images with high-angular resolution, 0.27 arcsec, now show very clearly the lensing object, a remote, elliptical galaxy, between the quasar images. The image displayed in ESO Press Photo 21/97 was obtained in the near-infrared J-band, where the lensing galaxy in HE 1104-1805 is quite faint, but still well visible and measurable after `deconvolution'. The observed, infrared colour, i.e. the difference in brightness of its image in the J- and K-bands (the (J-K) index ), is compatible with that of a high-redshift elliptical galaxy, at a distance corresponding to a redshift somewhere between z = 1 and z = 1.8. The brightest of the two quasar images (`A'; the upper one in ESO PR Photo 21/97) shows absorption lines in its spectrum which have been redshifted at z = 1.66. Since the lensing galaxy is situated at a small angular distance from this component, it is quite likely that these spectral lines are produced by this galaxy. Thus, the gravitational deflector in HE 1104-1805 is most probably an elliptical galaxy at redshift z = 1.66. This corresponds to a recession velocity of about 200,000 km/sec and a distance that, depending on the adopted Hubble relation, is of the order of 6,000 - 9,000 million light-years. Since this galaxy is comparatively bright in the infrared, this may be checked in the near future by taking an infrared spectrum, for example with the future IR instrument of the ESO New Technology Telescope, SOFI, cf. ESO Press Photo 17/97. Continued studies of HE 1104-1805 This gravitational lens is known to show brightness variations with time. It is therefore a good candidate for continued photometric monitoring which may possibly yield a new and independent determination of the Hubble constant [2], as this was recently done for another gravitational lens, PG 1115+080 [4]. If the lensing galaxy is actually located at redshift z = 1.66, then the time delay expected for brightness variations of the two lensed quasar images is of the order of 3 to 4 years, depending on the model. This should be easily measurable. A `Dark Lens' in HE 1104-1805? The observed geometry of HE 1104-1805 is somewhat surprising, since current lens models predict that the position of the deflector, as seen in the sky, is closer to the fainter quasar image than to the brighter one; here the contrary is the case. This would suggest that the distribution of the lensing matter is more complex than that of a single elliptical galaxy. In addition, the brightness of the lensing galaxy in the K-band is somewhat too high for a normal one. This may indicate the presence of a more massive object, for example a cluster of galaxies. This may not be the case, though, since the present, very deep observations would have allowed the detection of any normal cluster of galaxies between us and the quasar whose light is being split by the lens. An interesting question is therefore: do we `see' the effects of a lens of dark matter in HE 1104-1805? Only future observations, for instance with the ESO Very Large Telescope (VLT) , will tell. Where to find additional information More details about the image deconvolution techniques used for this investigation is available at the WWW pages of the Liege group. Information about another gravitational-lens related discovery by astronomers at the Institut d'Astrophysique in Liege have been reported in ESO Press Release 04/96 (9 February 1996). Notes: [1] The group consists of Frederic Courbin (Institut d'Astrophysique, Universite de Liege, Belgium, and Observatoire de Paris-Meudon, France) and Pierre Magain (Institut d'Astrophysique, Universite de Liege, Belgium) and Chris Lidman (ESO). [2] The careful observation of similar, but time-shifted brightness variations of the individual images of a quasar in a gravitational lens may sometimes lead to a determination of the distance to the lensing object (normally a distant galaxy). This is because the measured time delay of such variations (from some months to several years), from the known speed of light, will provide a direct indication of the difference in the length of the two light paths, expressed in kilometres. If moreover the overall distribution of the matter that causes the lensing effect is known (from observations of the shape of the lens) and thus the relative geometry of the lensing system and the light paths, it is then possible to estimate the absolute size of the system. When this is compared with its angular size (as seen in the sky on direct images), the true distance to the lensing object can be found. Dividing this distance with the measured recession velocity (along the line-of-sight), finally gives an independent value of the expansion rate of the Universe, the famous Hubble constant . [3] In astronomy, the redshift denotes the fraction by which the lines in the spectrum of an object are shifted towards longer wavelengths. The observed redshift of a distant galaxy or quasar gives a direct estimate of the apparent recession velocity as caused by the universal expansion. Since the expansion rate increases with the distance, the velocity is itself a function (the Hubble relation) of the distance to the object. A redshift of z = 1 corresponds to a recession velocity of 180,000 km/sec; z = 2 to 214,300 km/sec, z = 3 to 233,300 km/sec, and z = 4 to 245,500 km/sec; the non-proportionality is a relativistic effect. [4] Detailed information about PG 1115+080 may be found in the scientific papers by Schechter et al. (1997, ApJ, 475, L85) and Courbin et al. (1997, SISSA preprint astro-ph/9705093, A&A Letters, in press). Appendix: What is a gravitational lens? The physical principle behind a gravitational lens (also known as a cosmic mirage ) has been known since 1916 as a consequence of Einstein's General Relativity Theory. The gravitational field of a massive object curves the local geometry of the Universe, so light rays passing close to the object are also curved (in the same way as a `straight line' on the surface of the Earth is necessarily curved because of the curvature of the Earth's surface). This effect was first observed by astronomers in 1919 during a total solar eclipse. Accurate positional measurements of stars seen in the dark sky near the eclipsed Sun indicated an apparent displacement in the direction opposite to the Sun, about as much as predicted by the theory. The effect was obviously due to the gravitational attraction of the stellar photons when they passed near the Sun on their way to us. This was a direct confirmation of a new phenomenon and represented a milestone in physics. In the 1930's, astronomer Fritz Zwicky (1898 - 1974), of Swiss nationality and working at the Mount Wilson Observatory in California, realised that the same effect may also happen far out in space where galaxies and large galaxy clusters may be sufficiently compact and massive to bend the light from even more distant objects. However, it was only five decades later, in 1979, that his ideas were observationally confirmed when the first example of a cosmic mirage was discovered. In this connection, it is of particular interest, that this gravitational lensing effect may not only result in double or multiple images of the same object, but also that the intensities of these images increase significantly, just as it is the case with an ordinary optical lens. Distant galaxies, galaxy clusters, etc. may thereby act as natural telescopes which allow us to observe objects that would otherwise have been too faint to be detected with currently available astronomical telescopes. How to obtain ESO Press Information ESO Press Information is made available on the World-Wide Web (URL: http://www.eso.org../). ESO Press Photos may be reproduced, if credit is given to the European Southern Observatory.

  19. Eesti identiteedi kasv ja kasvatus 2006. aastal - Kumust Brotzeni / Mati Hint

    Index Scriptorium Estoniae

    Hint, Mati, 1937-

    2006-01-01

    Tallinna Ülikooli emeriitprofessori loetletud tippsündmused Eesti kunsti ja ajaloo valdkonnas 2006. a. - Kumu Kunstimuuseumi avamine, Kristjan ja Paul Raua näitus Kumus ning Riias tegutsenud baltisaksa kultuuriloolase Johann Christoph Brotze joonistuste kogumiku "Johann Christoph Brotze. Estonica." Koostanud Ants Hein, Ivar Leimus, Raimo Pullat, Ants Viires. Estopol OÜ 2006, ilmumine Tallinnas, peatoimetaja Raimo Pullat. Pikemalt eesti nüüdisaegsest kunstist Kumus ja rahvuslikust identiteedist

  20. Ignoring Memory Hints: The Stubborn Influence of Environmental Cues on Recognition Memory

    Science.gov (United States)

    Selmeczy, Diana; Dobbins, Ian G.

    2017-01-01

    Recognition judgments can benefit from the use of environmental cues that signal the general likelihood of encountering familiar versus unfamiliar stimuli. While incorporating such cues is often adaptive, there are circumstances (e.g., eyewitness testimony) in which observers should fully ignore environmental cues in order to preserve memory…

  1. Temporomandibular joint disorder complaints in tinnitus: further hints for a putative tinnitus subtype.

    Directory of Open Access Journals (Sweden)

    Veronika Vielsmeier

    Full Text Available OBJECTIVE: Tinnitus is considered to be highly heterogeneous with respect to its etiology, its comorbidities and the response to specific interventions. Subtyping is recommended, but it remains to be determined which criteria are useful, since it has not yet been clearly demonstrated whether and to which extent etiologic factors, comorbid states and interventional response are related to each other and are thus applicable for subtyping tinnitus. Analyzing the Tinnitus Research Initiative Database we differentiated patients according to presence or absence of comorbid temporomandibular joint (TMJ disorder complaints and compared the two groups with respect to etiologic factors. METHODS: 1204 Tinnitus patients from the Tinnitus Research Initiative (TRI Database with and without subjective TMJ complaints were compared with respect to demographic, tinnitus and audiological characteristics, questionnaires, and numeric ratings. Data were analysed according to a predefined statistical analysis plan. RESULTS: Tinnitus patients with TMJ complaints (22% of the whole group were significantly younger, had a lower age at tinnitus onset, and were more frequently female. They could modulate or mask their tinnitus more frequently by somatic maneuvers and by music or sound stimulation. Groups did not significantly differ for tinnitus duration, type of onset (gradual/abrupt, onset related events (whiplash etc., character (pulsatile or not, hyperacusis, hearing impairment, tinnitus distress, depression, quality of life and subjective ratings (loudness etc.. CONCLUSION: Replicating previous work in tinnitus patients with TMJ complaints, classical risk factors for tinnitus like older age and male gender are less relevant in tinnitus patients with TMJ complaints. By demonstrating group differences for modulation of tinnitus by movements and sounds our data further support the notion that tinnitus with TMJ complaints represents a subgroup of tinnitus with clinical features that are highly relevant for specific therapeutic management.

  2. Melatonin, Noncoding RNAs, Messenger RNA Stability and Epigenetics—Evidence, Hints, Gaps and Perspectives

    Science.gov (United States)

    Hardeland, Rüdiger

    2014-01-01

    Melatonin is a highly pleiotropic regulator molecule, which influences numerous functions in almost every organ and, thus, up- or down-regulates many genes, frequently in a circadian manner. Our understanding of the mechanisms controlling gene expression is actually now expanding to a previously unforeseen extent. In addition to classic actions of transcription factors, gene expression is induced, suppressed or modulated by a number of RNAs and proteins, such as miRNAs, lncRNAs, piRNAs, antisense transcripts, deadenylases, DNA methyltransferases, histone methylation complexes, histone demethylases, histone acetyltransferases and histone deacetylases. Direct or indirect evidence for involvement of melatonin in this network of players has originated in different fields, including studies on central and peripheral circadian oscillators, shift work, cancer, inflammation, oxidative stress, aging, energy expenditure/obesity, diabetes type 2, neuropsychiatric disorders, and neurogenesis. Some of the novel modulators have also been shown to participate in the control of melatonin biosynthesis and melatonin receptor expression. Future work will need to augment the body of evidence on direct epigenetic actions of melatonin and to systematically investigate its role within the network of oscillating epigenetic factors. Moreover, it will be necessary to discriminate between effects observed under conditions of well-operating and deregulated circadian clocks, and to explore the possibilities of correcting epigenetic malprogramming by melatonin. PMID:25310649

  3. Hints About Some Baseful but Indispensable Elements in Speech Recognition and Reconstruction

    Directory of Open Access Journals (Sweden)

    Mihaela Costin

    2002-07-01

    Full Text Available The cochlear implant (CI is a device used to reconstruct the hearing capabilities of a person diagnosed with total cophosis. This impairment may occur after some accidents, chemotherapy etc., the person still having an intact hearing nerve. The cochlear implant has two parts: a programmable, external part, the Digital Signal Processing (DSP device which process and transform the speech signal, and another surgically implanted part, with a certain number of electrodes (depending on brand used to stimulate the hearing nerve. The speech signal is fully processed in the DSP external device resulting the ``coded'' information on speech. This is modulated with the support of the fundamental frequency F0 and the energy impulses are inductively sent to the hearing nerve. The correct detection of this frequency is very important, determining the manner of hearing and making the difference between a "computer'' voice and a natural one. The results are applicable not only in the medical domain, but also in the Romanian speech synthesis.

  4. Thermoelectric Properties of TI – Doped SnSe: A Hint of Phononic Structure

    Czech Academy of Sciences Publication Activity Database

    Kucek, V.; Plecháček, T.; Janíček, P.; Ruleová, P.; Beneš, L.; Navrátil, Jiří; Drašar, Č.

    2016-01-01

    Roč. 45, č. 6 (2016), s. 2943-2949 ISSN 0361-5235 R&D Projects: GA ČR(CZ) GA16-07711S Institutional support: RVO:61389013 Keywords : semiconductors * chalcogenides * X-ray diffraction Subject RIV: CA - Inorganic Chemistry Impact factor: 1.579, year: 2016

  5. The Physiological Roles of Amyloid-β Peptide Hint at New Ways to Treat Alzheimer's Disease

    Directory of Open Access Journals (Sweden)

    Holly M. Brothers

    2018-04-01

    Full Text Available Amyloid-ß (Aß is best known as the misfolded peptide that is involved in the pathogenesis of Alzheimer's disease (AD, and it is currently the primary therapeutic target in attempts to arrest the course of this disease. This notoriety has overshadowed evidence that Aß serves several important physiological functions. Aß is present throughout the lifespan, it has been found in all vertebrates examined thus far, and its molecular sequence shows a high degree of conservation. These features are typical of a factor that contributes significantly to biological fitness, and this suggestion has been supported by evidence of functions that are beneficial for the brain. The putative roles of Aß include protecting the body from infections, repairing leaks in the blood-brain barrier, promoting recovery from injury, and regulating synaptic function. Evidence for these beneficial roles comes from in vitro and in vivo studies, which have shown that the cellular production of Aß rapidly increases in response to a physiological challenge and often diminishes upon recovery. These roles are further supported by the adverse outcomes of clinical trials that have attempted to deplete Aß in order to treat AD. We suggest that anti-Aß therapies will produce fewer adverse effects if the known triggers of Aß deposition (e.g., pathogens, hypertension, and diabetes are addressed first.

  6. Breastfeeding: Hints to Help You Get Off to a Good Start

    Science.gov (United States)

    ... Kids and Teens Pregnancy and Childbirth Women Men Seniors Your Health Resources Healthcare Management End-of-Life Issues Insurance & Bills Self Care Working With Your Doctor Drugs, Procedures & Devices Over-the- ...

  7. Kaire Kemp-Tishler : harmoonia moodsa ja vana vahel / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Eramu sisekujundus. Sisearhitekt Kaire Kemp-Tishler, tema kommentaarid. Arhitekt Vahur Sova. Kamina sepised tegi Heigo Jelle. Trepihallis Tiit Pääsukese maal "Orasnzh". Ill.: I ja II korruse plaan, 14 värv. vaadet

  8. Kaire Kemp-Tishler: "Igatsen luua midagi kole-ilusat" / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Kaire Kemp-Tishler (sünd. 1964) kodu sisekujunduse projekteerimisest, tasakaalust sisearhitektuuris, oma kodust. Kaire Kemp-Tishlerist, tema tehtud tööde loetelu. 1998. aastast teeb K. Kemp-Tishler koostööd Ea Andlaga, kellega koos asutas 2001. a. OÜ sisearhitektuuribüroo ArtAku. Ill.: K. Kemp-Tishleri värv. portree

  9. Developing an Intelligent Tutoring System That Has Automatically Generated Hints and Summarization for Algebra and Geometry

    Science.gov (United States)

    Li, Yatao; Zhao, Ke; Xu, Wei

    2015-01-01

    Intelligent tutoring systems (ITSs), which provide step-by-step guidance to students in problem-solving activities, have been shown to enhance student learning in a range of domains. However, they tend to be pre-established and cannot supply the tutoring function immediately from the diverse mathematical questions. The MITSAS (multiagent…

  10. Issue Brief #2: Metrics for Improving Cost Accountability (Hint: Not More Detailed Cost Accounting...)

    Science.gov (United States)

    Delta Project on Postsecondary Education Costs, Productivity and Accountability, 2009

    2009-01-01

    Most fiscal reporting focuses on revenues (whether or not they go to core purposes), tuition and fees, and financial aid. "How" the money is spent is something that remains shrouded in too much mystery. Several national efforts to address this problem have largely come to naught--probably because those common methodologies are simultaneously not…

  11. Evidence of earlier thyroid dysfunction in newly diagnosed oral lichen planus patients: a hint for endocrinologists.

    Science.gov (United States)

    Arduino, Paolo G; Karimi, Dora; Tirone, Federico; Sciannameo, Veronica; Ricceri, Fulvio; Cabras, Marco; Gambino, Alessio; Conrotto, Davide; Salzano, Stefano; Carbone, Mario; Broccoletti, Roberto

    2017-11-01

    The association between oral lichen planus (OLP) and hypothyroidism has been debated with conflicting results: some authors detected a statistically significant association between these two, while others did not confirm it. The aim of this study was to evaluate the thyroid status in patients with newly diagnosed OLP to test the null hypothesis that thyroid disease is not associated with an increased incidence of oral lesions, with a prospective case-control approach. A total of 549 patients have been evaluated, of whom 355 were female. Odds ratio (OR) and 95% confidence intervals (CIs) were obtained. Patients suffering from thyroid diseases were associated with an almost 3-fold increased odds of having OLP (OR 2.85, 95% CI: 1.65-4.94), after adjusting this analysis for age, gender, body mass index, smoking status, diabetes, hypertension and hepatitis C infection. It would be appropriate to further investigate the possible concomitance of OLP among patients with thyroid disorder; endocrinologists should be aware of this association, especially because OLP is considered a potentially malignant oral disorder. © 2017 The authors.

  12. An overview of MR arthrography with emphasis on the current technique and applicational hints and tips

    Energy Technology Data Exchange (ETDEWEB)

    Sahin, Guelden [Department of Radiology, Faculty of Medicine, Ankara University, Samanpazari, 06100 Ankara (Turkey)]. E-mail: gsahin@medicine.ankara.edu.tr; Demirtas, Mehmet [Department of Hand Surgery, Faculty of Medicine, Ankara University, Samanpazari, 06100 Ankara (Turkey)

    2006-06-15

    Magnetic resonance (MR) arthrography has been investigated in every major peripheral joint of the body, and has been proven to be effective in determining the integrity of intraarticular ligamentous and fibrocartilaginous structures and in the detection or assessment of osteochondral lesions and loose bodies in selected cases. Several methods could be used to create arthrogram effect during MR imaging, however, direct MR arthrography using diluted gadolinium as the contrast agent is the most commonly used technique and is the most reliable of all. MR arthrography is useful for demonstrating labrocapsular-ligamentous abnormalities and distinguishing partial thickness rotator cuff tears from focal full thickness tears in the shoulder, identifying or excluding recurrent tears following meniscal operations in the knee, demonstrating perforations of the triangular fibrocartilage complex (TFCC) and ligaments in the wrist, showing labral tears in the hip, diagnosing ligament tears in the ankle and identifying osteochondral lesions or loose bodies in any of the aforementioned joints. In this article, an overview of techniques of MR arthrography is provided with emphasis on direct MR arthrography using diluted gadolinium as the contrast agent. The current applications of the technique in major peripheral joints are reviewed, with emphasis given to the shoulder joint where the role of this technique has become well established.

  13. A 3.55 keV hint for decaying axion-like particle dark matter

    International Nuclear Information System (INIS)

    Jaeckel, Joerg; Ringwald, Andreas

    2014-02-01

    Recently, indications for an emission line at 3.55 keV have been found in the combined spectra of a large number of galaxy clusters and also in Andromeda. This line could not be identified with any known spectral line. It is tempting to speculate that it has its origin in the decay of a particle contributing all or part of the dark matter. In this note we want to point out that axion-like particles being all or part of the dark matter are an ideal candidate to produce such a feature. More importantly the parameter values necessary are quite feasible in extensions of the Standard Model based on string theory and could be linked up to a variety of other intriguing phenomena, which also potentially allow for new tests of this speculation.

  14. Hints of Habitable Environments on Mars Challenge Our Studies of Mars-Analog Sites on Earth

    Science.gov (United States)

    desMarais, David J

    2009-01-01

    Life as we know it requires water with a chemical activity (alpha) >or approx.0.6 and sources of nutrients and useful energy. Some biota can survive even if favorable conditions occur only intermittently, but the minimum required frequency of occurrences is poorly understood. Recent discoveries have vindicated the Mars exploration strategy to follow the water. Mars Global Surveyor s Thermal Emission Spectrometer (TES) found coarse-grained hematite at Meridiani Planum. Opportunity rover confirmed this and also found evidence of ancient sulfate-rich playa lakes and near-surface groundwater. Elsewhere, TES found evidence of evaporitic halides in topographic depressions. But alpha might not have approached 0.6 in these evaporitic sulfate- and halide-bearing waters. Mars Express (MEX) and Mars Reconnaissance Orbiter (MRO) found extensive sulfate evaporites in Meridiani and Valles Marineris. MEX found phyllosilicates at several sites, most notably Mawrth Valles and Nili Fossae. MRO's CRISM near-IR mapper extended the known diversity and geographic distribution of phyllosilicates to include numerous Noachian craters. Phyllosilicates typically occur at the base of exposed ancient rock sections or in sediments in early Hesperian craters. It is uncertain whether the phyllosilicates developed in surface or subsurface aqueous environments and how long aqueous conditions persisted. Spirit rover found remarkably pure ferric sulfate, indicating oxidation and transport of Fe and S, perhaps in fumaroles or hot springs. Spirit also found opaline silica, consistent with hydrothermal activity. CRISM mapped extensive silica deposits in the Valles Marineris region, consistent with aqueous weathering and deposition. CRISM also found ultramafic rocks and magnesite at Nili Fossae, consistent with serpentinization, a process that can sustain habitable environments on Earth. The report of atmospheric methane implies subsurface aqueous conditions. A working hypothesis is that aqueous environments persisted in the near-subsurface for hundreds of millions of years and might exist even today. Studies of Mars-analog environments must better understand subsurface nonphotosynthetic ecosystems and their biosignatures in mafic and ultramafic terranes. Studies must determine minimum needs for water activity and energy and also establish survival limits when conditions that support active metabolism and propagation become progressively less frequent over time.

  15. Squint surgery in TED -- hints and fints, or why Graves' patients are difficult patients.

    Science.gov (United States)

    Nardi, M

    2009-01-01

    Endocrine ophthalmopathy is the most common cause of acute onset diplopia in middle aged or older individuals. Ocular muscle involvement is characterized by myositis followed by fibrosis: this causes a stiffness and a shortening of the muscles involved with restriction of ocular movements: so the impairment of rotation is due to a mechanical obstacle and not to a paresis. Prisms are rarely useful in relieving diplopia and the majority of symptomatic patients need squint surgery. Timing of surgery is very important and two considerations are to be kept in mind: first, the systemic disease must be in remission and the ocular deviation must be stable for at least six months; second, if more than one surgical procedure is needed for the ophthalmopathy, muscle surgery has its right place after orbital surgery and before lid surgery. Obviously dealing with restrictive disorders, surgery is based on weakening procedures of the affected muscles: identifying the affected muscles is of crucial importance and may be sometime difficult for the presence of misleading signs; great advances have been made in surgical technique with the development of adjustable sutures and of topical anesthesia. Prognosis is usually good with more than 80% of patients recovering a useful field of binocular single vision with one procedure and more than 90% with two or more procedures.

  16. Hints on the Broad Line Region Structure of Quasars at High and Low Luminosities

    Directory of Open Access Journals (Sweden)

    Marziani Paola

    2011-09-01

    Full Text Available Quasars show a considerable spectroscopic diversity. However, the variety of quasar spectra at low redshifts is non-random: a principal component analysis applied to large samples customarily identifies two main eigenvectors. In this contribution we show that the range of quasar optical spectral properties observed at low-z and associated with the first eigenvector is preserved up to z ≈ 2 in a sample of high luminosity quasars. We also describe two major luminosity effects.

  17. Is the Earth's magnetic field heading for a flip? Hints from the past

    Science.gov (United States)

    Laj, C. E.; Kissel, C.

    2017-12-01

    The magnitude of the Earth's dipole magnetic field has decreased significantly over the last centuries at a mean rate of 16 nT/y. This decrease, which correlates with the growth of the South Atlantic Anomaly (SAA) therefore occurs at a rate which is about 10 times larger than expected from a free Ohmic decay process. This situation has led to speculations that an attempt to a reversal or a geomagnetic excursion might be underway. We investigate this hypothesis by examining past geomagnetic instabilities, focussing on the well documented Laschamp and Mono Lake excursions. We have selected high accumulation sedimentary records with very precise age model, leading to unprecedented temporal resolution, and accurate calibration of RPI between 20 and 75 kyr B.P. We also used the 10Be and 36Cl records from the Greenland ice cores. The rate of decay of the field intensity during these two excursions is virtually identical to that observed over the last centuries and much higher than that observed for another period of low intensity (around 65 kyr BP) not associated with a polarity change. Moreover, the global morphology of the Laschamp excursion obtained by Bayesian inversion (Leonhardt et al. (2009) is that reverse magnetic field patches at the core-mantle boundary are formed near the equator and then move poleward, a scenario reminiscent of that described for the present field in the litterature. Therefore, although these results from two excursions do not provide undisputable information on future evolution of the field, they show similarities with several aspects of the present-day geomagnetic field. Assuming that the dynamo processes for an eventual future instability would be similar to those of the past two excursions, we tentatively suggest that, whilst irreversible processes that will drive the geodynamo into a polarity change may have already started, some 1000 years would be needed for the directional changes to start to be significant.

  18. Human airway epithelial cells investigated by atomic force microscopy: A hint to cystic fibrosis epithelial pathology

    International Nuclear Information System (INIS)

    Lasalvia, Maria; Castellani, Stefano; D’Antonio, Palma; Perna, Giuseppe; Carbone, Annalucia; Colia, Anna Laura; Maffione, Angela Bruna; Capozzi, Vito; Conese, Massimo

    2016-01-01

    The pathophysiology of cystic fibrosis (CF) airway disease stems from mutations in the CF Transmembrane Conductance Regulator (CFTR) gene, leading to a chronic respiratory disease. Actin cytoskeleton is disorganized in CF airway epithelial cells, likely contributing to the CF-associated basic defects, i.e. defective chloride secretion and sodium/fluid hypersorption. In this work, we aimed to find whether this alteration could be pointed out by means of Atomic Force Microscopy (AFM) investigation, as roughness and Young's elastic module. Moreover, we also sought to determine whether disorganization of actin cytoskeleton is linked to hypersoption of apical fluid. Not only CFBE41o- (CFBE) cells, immortalized airway epithelial cells homozygous for the F508del CFTR allele, showed a different morphology in comparison with 16HBE14o- (16HBE) epithelial cells, wild-type for CFTR, but also they displayed a lack of stress fibers, suggestive of a disorganized actin cytoskeleton. AFM measurements showed that CFBE cells presented a higher membrane roughness and decreased rigidity as compared with 16HBE cells. CFBE overexpressing wtCFTR became more elongated than the parental CFBE cell line and presented actin stress fibers. CFBE cells absorbed more fluid from the apical compartment. Study of fluid absorption with the F-actin-depolymerizing agent Latrunculin B demonstrated that actin cytoskeletal disorganization increased fluid absorption, an effect observed at higher magnitude in 16HBE than in CFBE cells. For the first time, we demonstrate that actin cytoskeleton disorganization is reflected by AFM parameters in CF airway epithelial cells. Our data also strongly suggest that the lack of stress fibers is involved in at least one of the early step in CF pathophysiology at the levels of the airways, i.e. fluid hypersorption. - Highlights: • CF bronchial epithelial (CFBE) cells show a disorganized actin cytoskeleton. • CFBE cells present high roughness and low rigidity in the plasmamembrane. • CFTR overexpression changes morphology and actin organization. • CFBE cells absorb more apical fluid than wild type bronchial epithelial cells. • Fluid absorption is increased by disorganization of actin cytoskeleton.

  19. Robustness of circadian clocks to daylight fluctuations: hints from the picoeucaryote Ostreococcus tauri.

    Directory of Open Access Journals (Sweden)

    Quentin Thommen

    Full Text Available The development of systemic approaches in biology has put emphasis on identifying genetic modules whose behavior can be modeled accurately so as to gain insight into their structure and function. However, most gene circuits in a cell are under control of external signals and thus, quantitative agreement between experimental data and a mathematical model is difficult. Circadian biology has been one notable exception: quantitative models of the internal clock that orchestrates biological processes over the 24-hour diurnal cycle have been constructed for a few organisms, from cyanobacteria to plants and mammals. In most cases, a complex architecture with interlocked feedback loops has been evidenced. Here we present the first modeling results for the circadian clock of the green unicellular alga Ostreococcus tauri. Two plant-like clock genes have been shown to play a central role in the Ostreococcus clock. We find that their expression time profiles can be accurately reproduced by a minimal model of a two-gene transcriptional feedback loop. Remarkably, best adjustment of data recorded under light/dark alternation is obtained when assuming that the oscillator is not coupled to the diurnal cycle. This suggests that coupling to light is confined to specific time intervals and has no dynamical effect when the oscillator is entrained by the diurnal cycle. This intriguing property may reflect a strategy to minimize the impact of fluctuations in daylight intensity on the core circadian oscillator, a type of perturbation that has been rarely considered when assessing the robustness of circadian clocks.

  20. Avalikustamiskohustuse rikkumine Eesti väärtpaberituruõiguses : tsiviilõiguslikud kaitsevahendid / Meelis Hint

    Index Scriptorium Estoniae

    Hint, Meelis, 1981-

    2003-01-01

    Väärtpaberite avalikustamiskohustusest, tehingu tühistamisest, kahju hüvitamisest, väärtpaberite müügist, kahju hüvitamisest rikkumiste korral ja tehingu tühistamisest väärtpaberite järelturul

  1. Hints on the Lateralization of Dopamine Binding to D-1 Receptors in Rat Striatum

    Czech Academy of Sciences Publication Activity Database

    Franco, R.; Casadó-Anguera, V.; Muňoz, A.; Petrovič, Miloš; Navarro, G.; Moreno, E.; Lanciego, J. L.; Labandeira-García, J. L.; Cortés, A.; Casadó, V.

    2016-01-01

    Roč. 53, č. 8 (2016), s. 5436-5445 ISSN 0893-7648 Institutional support: RVO:67985823 Keywords : lateralization * basal ganglia * G-protein-coupled receptor dimer * dyskinesia * 6-hydroxydopamine Subject RIV: ED - Physiology Impact factor: 6.190, year: 2016

  2. Dark matter searches from the galaxy to the LHC - recent hints and coming progress

    CERN Multimedia

    CERN. Geneva

    2008-01-01

    We discuss the possible galactic positron excess and constraints on interpreting it as dark matter annihilation. We consider wino and higgsino wimps that provide the local relic density and a positron excess (which implies the relic density is non-thermal in origin and important consequences for cosmological history and underlying theories), comment on how to confirm and study these issues at LHC, and on the relation to direct detection experiments.

  3. Mati Hint - sünge keeleteadlane ja pessimistlik ühiskonnategelane / Mari Klein

    Index Scriptorium Estoniae

    Klein, Mari, 1979-

    2007-01-01

    11. septembril peeti Tallinna Ülikoolis seminari, mis oli pühendatud Mati Hindi 70. sünnipäevale. Ettekannetega esinesid ülikoolikaaslased, sõbrad ja kolleegid Rein Veidemann, Haldur Õim, Martin Ehala, Mats Traat, Tapani Lehtinen, Jaan Kaplinski

  4. The new elastic scattering measurements of TOTEM -Are there hints for asymptotics?

    Science.gov (United States)

    Troshin, Sergey M.; Tyurin, Nikolai E.

    2017-03-01

    We point out to another indication of the black-disk limit exceeding in hadron interactions found in the recent impact parameter analysis performed by the TOTEM Collaboration at √{s}=8 TeV and emphasize that this observation might be interpreted as a confirmation of the reflective scattering mode appearance at the LHC energies.

  5. Andro Kööp : "Püüan ruumi tunnet maalida" / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Andro Kööp (sünd. 1967) sellest, kuidas ta sattus sisearhitektuuriga tegelema, oma eelistustest ja harmooniast sisekujunduses, kodu kujundusest jm. A. Kööbist, tema loomingust, omistatud preemiad, valik A. Kööbi kujundatud ühiskondlikke interjööre. Ill.: värv. foto A. Kööbist

  6. Hints on the high-energy seesaw mechanism from the low-energy neutrino spectrum

    International Nuclear Information System (INIS)

    Casas, J.A.; Jimenez-Alburquerque, F.

    2006-12-01

    It is an experimental fact that the mass ratio for the two heavier neutrinos, h=m 3 /m 2 3 /m 2 >> m 3 /m 2 , so m 1 should be extremely tiny. Also, the V R matrix associated to the neutrino Yukawa couplings has a far from random structure, naturally resembling V CKM . In fact we show that identifying V R and V CKM , as well as neutrino and u-quark Yukawa couplings can reproduce h exp in a highly non-trivial way, which is very suggestive. The physical implications of these results are also discussed. (orig.)

  7. Andro Kööp : villa, mis sai ajaloo / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Saaremaal asuva arhitekt Ike Volkovi projekti järgi ehitatud villa sisekujundus. Sisearhitekt Andro Kööp, tema kommentaarid. A. Kööp on kavandanud ka vaibad. Suures osas on villa sisekujunduses kasutatud kataloogimööblit. Ill.: I ja II korruse plaan, 17 värv. vaadet

  8. 3rd Circuit hints it may reconsider McNemar reasoning.

    Science.gov (United States)

    1997-10-17

    The [name removed] v. The Disney Store ruling is under criticism and the 3rd U.S. Circuit Court of Appeals may reconsider its 1996 decision to not allow employees who receive disability benefits to sue under the Americans with Disabilities Act (ADA). A panel of 3rd Circuit judges, working on [name removed] v. American Sterilizer Co., asserts that the [name removed] decision should not be used to assume that an individual's ADA claims are barred because of prior representations of disability. [Name removed] is suing American Sterilizer under the retaliation provisions of the ADA. Other courts are criticizing the [name removed] decision, including the District of Columbia Court in [name removed] v. Washington Metropolitan Area Transit Authority. The [name removed] court assets that a statement made in the context of a disability application does not preclude an ADA claim brought by a worker for illegal discrimination because the ADA and the Social Security Act differ in their statutory intent. AIDS advocates state that the [name removed] decision places a plaintiff in the position of having to choose between asserting a legal right or maintaining an income. Alan Epstein, who represented [name removed], is pleased by the criticism but explains that [name removed], who died this summer, will not be vindicated.

  9. Mari Koger : avatud magamistoaga korter pööningukorrusel / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Korter Nõmmel renoveeritud puumajas (arhitekt Hannes Niineväli). Sisearhitekt Mari Koger, tema kommentaarid. Söögilaua alumiiniumist valatud jalgade autor on Taavi Aunre. Söögilauda valgustab Alberto Meda ja Paolo Rizzatto disainitud lamp Titania. Ill.: plaan, 8 värv. vaadet

  10. The bioethics and law paradox: an argument to maintain separateness with a hint of togetherness.

    Science.gov (United States)

    Werren, Julia

    2007-10-01

    This article analyses how bioethics and law interact and work together. The first half of the article provides definitions of both ethics and bioethics. The article then considers a number of different bioethical standpoints to demonstrate the variance of views in relation to bioethics. In addition, the first half of the article focuses on the different regulatory possibilities in regard to bioethical contexts. This demonstrates that law is of central importance to bioethics. This part also shows that even though law and ethics are often used simultaneously to achieve bioethical goals, law and ethics cannot be used interchangeably. Thus, even though it is somewhat inevitable that law will be used in the pursuit of the goals of bioethics, bioethics and bioethical principle should not be merely a vehicle for law-makers to utilise. The second half of the article focuses on the issues of autonomy and consent to demonstrate how law and ethics have developed in one of the foundation areas of bioethics.

  11. Perceptual strategies of pigeons to detect a rotational centre--a hint for star compass learning?

    Directory of Open Access Journals (Sweden)

    Bianca Alert

    Full Text Available Birds can rely on a variety of cues for orientation during migration and homing. Celestial rotation provides the key information for the development of a functioning star and/or sun compass. This celestial compass seems to be the primary reference for calibrating the other orientation systems including the magnetic compass. Thus, detection of the celestial rotational axis is crucial for bird orientation. Here, we use operant conditioning to demonstrate that homing pigeons can principally learn to detect a rotational centre in a rotating dot pattern and we examine their behavioural response strategies in a series of experiments. Initially, most pigeons applied a strategy based on local stimulus information such as movement characteristics of single dots. One pigeon seemed to immediately ignore eccentric stationary dots. After special training, all pigeons could shift their attention to more global cues, which implies that pigeons can learn the concept of a rotational axis. In our experiments, the ability to precisely locate the rotational centre was strongly dependent on the rotational velocity of the dot pattern and it crashed at velocities that were still much faster than natural celestial rotation. We therefore suggest that the axis of the very slow, natural, celestial rotation could be perceived by birds through the movement itself, but that a time-delayed pattern comparison should also be considered as a very likely alternative strategy.

  12. How Parents Influence School Grades: Hints from a Sample of Adoptive and Biological Families

    Science.gov (United States)

    Johnson, Wendy; McGue, Matt; Iacono, William G.

    2007-01-01

    Using the biological and adoptive families in the Minnesota-based Sibling Interaction and Behavior Study, we investigated the associations among genetic and environmental influences on IQ, parenting, parental expectations for offspring educational attainment, engagement in school, and school grades. All variables showed substantial genetic…

  13. Estimating Dynamical Systems: Derivative Estimation Hints from Sir Ronald A. Fisher

    Science.gov (United States)

    Deboeck, Pascal R.

    2010-01-01

    The fitting of dynamical systems to psychological data offers the promise of addressing new and innovative questions about how people change over time. One method of fitting dynamical systems is to estimate the derivatives of a time series and then examine the relationships between derivatives using a differential equation model. One common…

  14. Using the ERT method in tectonically active areas: hints from Southern Apennine (Italy

    Directory of Open Access Journals (Sweden)

    A. Giocoli

    2008-11-01

    Full Text Available Electrical Resistivity Tomography (ERT method has been used to study two tectonically active areas of southern Apennine (Caggiano Faults and Ufita Basin. The main aim of this job was to study the structural setting of the investigated areas, i.e. the geometry of the basins at depth, the location of active faults at surface, and their geometrical characterization. The comparison between ERT and trench/drilling data allowed us to evaluate the efficacy of the ERT method in studying active faults and the structural setting of seismogenic areas.

    In the Timpa del Vento intermontane basin, high resolution ERT across the Caggiano Fault scarps, with different arrays, electrode spacing (from 1 to 10 m and penetration depth (from about 5 to 40 m was carried out. The obtained resistivity models allowed us to locate the fault planes along the hillslope and to gather information at depth, as later confirmed by paleoseismological trenches excavated across the fault trace.

    In the Ufita River Valley a 3560-m-long ERT was carried out across the basin, joining 11 roll-along multi-channel acquisition system with an electrode spacing of 20 m and reaching an investigation depth of about 170 m. The ERT allowed us to reconstruct the geometry and thickness of the Quaternary deposits filling the Ufita Valley. Our reconstruction of the depositional setting is in agreement with an interpretative geological section based on borehole data.

  15. Flexibility of approach in art practice as research: Hints in Omabe ...

    African Journals Online (AJOL)

    Recently, a number of art institutions (universities) in Europe, America, Asia, and Africa, introduced doctorate programme in studio areas, in which art practice is considered as research. As a new ... installation. The installations elicited public discourse on the tradition and a language of practice stood out from them.

  16. Eesti film - needusega? / Margot Visnap

    Index Scriptorium Estoniae

    Visnap, Margot, 1959-

    2006-01-01

    Mängufilm "Libahundi needus" : stsenaristid Margus Kasterpalu, Ilmar Raag ja Rainer Sarnet : režissöör Rainer Sarnet : osades Katariina Lauk, Rene Reinumägi, Raine Loo, Kersti Kreismann, Marje Metsur, Tiit Lilleorg : Shop of Dreams - Eesti Televisioon 2005

  17. Kas võidab teater või sihikindel needus ? / Matis Song

    Index Scriptorium Estoniae

    Song, Matis, 1978-

    2006-01-01

    Mängufilm "Libahundi needus" : stsenaristid Margus Kasterpalu, Ilmar Raag ja Rainer Sarnet : režissöör Rainer Sarnet : osades Katariina Lauk, Rene Reinumägi, Raine Loo, Kersti Kreismann, Marje Metsur, Tiit Lilleorg : Shop of Dreams - Eesti Televisioon 2005

  18. President Meri annetas aumärke

    Index Scriptorium Estoniae

    1996-01-01

    Riigivapi I klassi orden Jaan Krossile ja Kalju Lepikule; Riigivapi III klassi orden Ain Kaalepile, Hilja Rüütlile (Aili Helm); Riigivapi IV klassi orden Voldemar Millerile, Juhan Peeglile ja Ants Viiresele

  19. Peeter Allik, Urmas Viik jt Londonis

    Index Scriptorium Estoniae

    2006-01-01

    Eesti, Läti ja Leedu graafikute näitus "Power and Man. Three Countries. One Exhibition" galeriis Novas Gallery. Eestist osalevad Peeter Allik, Urmas Viik, Jaak Visnap, Kadri Alesmaa, Aili Vahtrapuu, Inga Heamägi

  20. Puitpitsvilla meenutab kunagisi hiilgeaegu / Mari Rebane

    Index Scriptorium Estoniae

    Rebane, Mari

    2004-01-01

    2003. a. Tartus väljaantud arhitektuuriraamat "Puitpitsvilla" eksponeerib Narva-Jõesuu puitvillasid. Pildid on Tartu Kõrgema Kunstikooli lõpetanud fotograafidelt Liisi Siibakult ja Aili Paadilt, saatesõna Tartu Ülikooli doktorandilt arhitektuuriajaloolaselt Epi Tohvrilt

  1. Miks tuli "Kevade" läinud aastal teisiti / Mare Müürsepp

    Index Scriptorium Estoniae

    Müürsepp, Mare

    2008-01-01

    "Aasta rosina" auhinna võitnud Oskar Lutsu "Kevade" kommenteeritud kooliväljaandest "Kui Arno isaga koolimajja jõudis..." (Tallinn : Ilo, 2007), mille koostasid Aili Kalavus ja Mare Müürsepp ning illustreeris Mare Hunt

  2. Cultural Trauma and Life Stories / Ene Kõresaar

    Index Scriptorium Estoniae

    Kõresaar, Ene

    2007-01-01

    Aili Aarelaid-Tarti 15-aastase uuringu tulemused raamatus "Cultural Trauma and Life Stories", Hesinki, Kikimora Publications, 2006. Uuritud on kolme suurt rahvusgruppi 1940-test tingitud trauma kontekstis: eestlased kodumaal, eestlased eksiilis ja venekeelne rahvusgrupp Eestis postsovetlikus diskursuses

  3. Taarausuliste haigla jääb personalita / Katrin Pauts

    Index Scriptorium Estoniae

    Pauts, Katrin, 1977-

    2001-01-01

    Taarausuliste liider Rootsi eestlane Addold Mossin soovib Valgamaale rajada erihaigla, kus arstide kõrval hakkavad inimesi ravima ka nõiad. Professor Aili Paju ei kavatse taarausuliste haiglasse tööle minna

  4. THE PUZZLING EARLY DETECTION OF LOW VELOCITY 56Ni DECAY LINES IN SN 2014J: HINTS OF A COMPACT REMNANT

    International Nuclear Information System (INIS)

    Ouyed, Rachid; Leahy, Denis; Koning, Nico; Staff, Jan

    2015-01-01

    We show that the low-velocity 56 Ni decay lines detected earlier than expected in the type Ia SN 2014J find an explanation in the quark-nova Ia model, which involves the thermonuclear explosion of a tidally disrupted sub-Chandrasekhar white dwarf (WD) in a tight neutron-star-WD binary system. The explosion is triggered by impact from the quark-nova (QN) ejecta on the WD material; the QN is the explosive transition of the neutron star to a quark star (QS) triggered by accretion from a CO torus (the circularized WD material). The presence of a compact remnant (the QS) provides: (1) an additional energy source (spin-down power) which allows us to fit the observed light-curve including the steep early rise; (2) a central gravitational potential which slows down some of the 56 Ni produced to velocities of a few 10 3 km s –1 . In our model, the 56 Ni decay lines become optically visible at ∼20 days from explosion time in agreement with observations. We list predictions that can provide important tests for our model

  5. Gamma-ray and X-ray emission from the Galactic centre: hints on the nuclear star cluster formation history

    Science.gov (United States)

    Arca-Sedda, Manuel; Kocsis, Bence; Brandt, Timothy D.

    2018-06-01

    The Milky Way centre exhibits an intense flux in the gamma and X-ray bands, whose origin is partly ascribed to the possible presence of a large population of millisecond pulsars (MSPs) and cataclysmic variables (CVs), respectively. However, the number of sources required to generate such an excess is much larger than what is expected from in situ star formation and evolution, opening a series of questions about the formation history of the Galactic nucleus. In this paper we make use of direct N-body simulations to investigate whether these sources could have been brought to the Galactic centre by a population of star clusters that underwent orbital decay and formed the Galactic nuclear star cluster (NSC). Our results suggest that the gamma ray emission is compatible with a population of MSPs that were mass segregated in their parent clusters, while the X-ray emission is consistent with a population of CVs born via dynamical interactions in dense star clusters. Combining observations with our modelling, we explore how the observed γ ray flux can be related to different NSC formation scenarios. Finally, we show that the high-energy emission coming from the galactic central regions can be used to detect black holes heavier than 105M⊙ in nearby dwarf galaxies.

  6. Preliminary numerical simulations of the 27 February 2010 Chile tsunami: first results and hints in a tsunami early warning perspective

    Science.gov (United States)

    Tinti, S.; Tonini, R.; Armigliato, A.; Zaniboni, F.; Pagnoni, G.; Gallazzi, Sara; Bressan, Lidia

    2010-05-01

    The tsunamigenic earthquake (M 8.8) that occurred offshore central Chile on 27 February 2010 can be classified as a typical subduction-zone earthquake. The effects of the ensuing tsunami have been devastating along the Chile coasts, and especially between the cities of Valparaiso and Talcahuano, and in the Juan Fernandez islands. The tsunami propagated across the entire Pacific Ocean, hitting with variable intensity almost all the coasts facing the basin. While the far-field propagation was quite well tracked almost in real-time by the warning centres and reasonably well reproduced by the forecast models, the toll of lives and the severity of the damage caused by the tsunami in the near-field occurred with no local alert nor warning and sadly confirms that the protection of the communities placed close to the tsunami sources is still an unresolved problem in the tsunami early warning field. The purpose of this study is two-fold. On one side we perform numerical simulations of the tsunami starting from different earthquake models which we built on the basis of the preliminary seismic parameters (location, magnitude and focal mechanism) made available by the seismological agencies immediately after the event, or retrieved from more detailed and refined studies published online in the following days and weeks. The comparison with the available records of both offshore DART buoys and coastal tide-gauges is used to put some preliminary constraints on the best-fitting fault model. The numerical simulations are performed by means of the finite-difference code UBO-TSUFD, developed and maintained by the Tsunami Research Team of the University of Bologna, Italy, which can solve both the linear and non-linear versions of the shallow-water equations on nested grids. The second purpose of this study is to use the conclusions drawn in the previous part in a tsunami early warning perspective. In the framework of the EU-funded project DEWS (Distant Early Warning System), we will try to give some clues for discussion on the deficiencies of the existing tsunami early warning concepts as regards the warning to the areas which are found close to the tsunami source, and on the strategies that should be followed in the near future in order to make significant progress in the protection and safeguarding of local communities.

  7. 76 FR 37356 - Submission for OMB review; comment request Health Information National Trends Survey 4 (HINTS 4...

    Science.gov (United States)

    2011-06-27

    ...) (OMB 0925-0538, Exp 11/30/2008). Type of Information Collection Request: Reinstatement with Change... understand vital cancer prevention messages. More importantly, this NCI survey will couple knowledge-related... assessment of cancer-related behavior. The Public Health Services Act, Sections 411 (42 U.S.C. 285a) and 412...

  8. When can Empirical Green Functions be computed from Noise Cross-Correlations? Hints from different Geographical and Tectonic environments

    Science.gov (United States)

    Matos, Catarina; Silveira, Graça; Custódio, Susana; Domingues, Ana; Dias, Nuno; Fonseca, João F. B.; Matias, Luís; Krueger, Frank; Carrilho, Fernando

    2014-05-01

    Noise cross-correlations are now widely used to extract Green functions between station pairs. But, do all the cross-correlations routinely computed produce successful Green Functions? What is the relationship between noise recorded in a couple of stations and the cross-correlation between them? During the last decade, we have been involved in the deployment of several temporary dense broadband (BB) networks within the scope of both national projects and international collaborations. From 2000 to 2002, a pool of 8 BB stations continuously operated in the Azores in the scope of the Memorandum of Understanding COSEA (COordinated Seismic Experiment in the Azores). Thanks to the Project WILAS (West Iberia Lithosphere and Astenosphere Structure, PTDC/CTE-GIX/097946/2008) we temporarily increased the number of BB deployed in mainland Portugal to more than 50 (permanent + temporary) during the period 2010 - 2012. In 2011/12 a temporary pool of 12 seismometers continuously recorded BB data in the Madeira archipelago, as part of the DOCTAR (Deep Ocean Test Array Experiment) project. Project CV-PLUME (Investigation on the geometry and deep signature of the Cape Verde mantle plume, PTDC/CTE-GIN/64330/2006) covered the archipelago of Cape Verde, North Atlantic, with 40 temporary BB stations in 2007/08. Project MOZART (Mozambique African Rift Tomography, PTDC/CTE-GIX/103249/2008), covered Mozambique, East Africa, with 30 temporary BB stations in the period 2011 - 2013. These networks, located in very distinct geographical and tectonic environments, offer an interesting opportunity to study seasonal and spatial variations of noise sources and their impact on Empirical Green functions computed from noise cross-correlation. Seismic noise recorded at different seismic stations is evaluated by computation of the probability density functions of power spectral density (PSD) of continuous data. To assess seasonal variations of ambient noise sources in frequency content, time-series of PSD at different frequency bands have been computed. The influence of the spatial and seasonal variation is evaluated by analysis of the one-day length cross-correlations, stacked with a 30-day moving window and with an overlap of 30 days. To inspect the effects of frequency content variations, 30-day cross-correlograms have also been computed at different frequency bands. This work is supported by project QuakeLoc-PT (PTDC/GEO-FIQ/3522/2012) and a contribution to project AQUAREL (PTDC/CTE-GIX/116819/2010).

  9. Simple heuristics in over-the-counter drug choices: a new hint for medical education and practice.

    Science.gov (United States)

    Riva, Silvia; Monti, Marco; Antonietti, Alessandro

    2011-01-01

    Over-the-counter (OTC) drugs are widely available and often purchased by consumers without advice from a health care provider. Many people rely on self-management of medications to treat common medical conditions. Although OTC medications are regulated by the National and the International Health and Drug Administration, many people are unaware of proper dosing, side effects, adverse drug reactions, and possible medication interactions. This study examined how subjects make their decisions to select an OTC drug, evaluating the role of cognitive heuristics which are simple and adaptive rules that help the decision-making process of people in everyday contexts. By analyzing 70 subjects' information-search and decision-making behavior when selecting OTC drugs, we examined the heuristics they applied in order to assess whether simple decision-making processes were also accurate and relevant. Subjects were tested with a sequence of two experimental tests based on a computerized Java system devised to analyze participants' choices in a virtual environment. We found that subjects' information-search behavior reflected the use of fast and frugal heuristics. In addition, although the heuristics which correctly predicted subjects' decisions implied significantly fewer cues on average than the subjects did in the information-search task, they were accurate in describing order of information search. A simple combination of a fast and frugal tree and a tallying rule predicted more than 78% of subjects' decisions. The current emphasis in health care is to shift some responsibility onto the consumer through expansion of self medication. To know which cognitive mechanisms are behind the choice of OTC drugs is becoming a relevant purpose of current medical education. These findings have implications both for the validity of simple heuristics describing information searches in the field of OTC drug choices and for current medical education, which has to prepare competent health specialists to orientate and support the choices of their patients.

  10. Simple heuristics in over-the-counter drug choices: a new hint for medical education and practice

    Science.gov (United States)

    Riva, Silvia; Monti, Marco; Antonietti, Alessandro

    2011-01-01

    Introduction Over-the-counter (OTC) drugs are widely available and often purchased by consumers without advice from a health care provider. Many people rely on self-management of medications to treat common medical conditions. Although OTC medications are regulated by the National and the International Health and Drug Administration, many people are unaware of proper dosing, side effects, adverse drug reactions, and possible medication interactions. Purpose This study examined how subjects make their decisions to select an OTC drug, evaluating the role of cognitive heuristics which are simple and adaptive rules that help the decision-making process of people in everyday contexts. Subjects and methods By analyzing 70 subjects’ information-search and decision-making behavior when selecting OTC drugs, we examined the heuristics they applied in order to assess whether simple decision-making processes were also accurate and relevant. Subjects were tested with a sequence of two experimental tests based on a computerized Java system devised to analyze participants’ choices in a virtual environment. Results We found that subjects’ information-search behavior reflected the use of fast and frugal heuristics. In addition, although the heuristics which correctly predicted subjects’ decisions implied significantly fewer cues on average than the subjects did in the information-search task, they were accurate in describing order of information search. A simple combination of a fast and frugal tree and a tallying rule predicted more than 78% of subjects’ decisions. Conclusion The current emphasis in health care is to shift some responsibility onto the consumer through expansion of self medication. To know which cognitive mechanisms are behind the choice of OTC drugs is becoming a relevant purpose of current medical education. These findings have implications both for the validity of simple heuristics describing information searches in the field of OTC drug choices and for current medical education, which has to prepare competent health specialists to orientate and support the choices of their patients. PMID:23745077

  11. The Orientalisation of North Africa: New hints from the study of autosomal STRs in an Arab population.

    Science.gov (United States)

    Elkamel, Sarra; Cherni, Lotfi; Alvarez, Luis; Marques, Sofia L; Prata, Maria J; Boussetta, Sami; Benammar-Elgaaied, Amel; Khodjet-El-Khil, Houssein

    2017-03-01

    Recent genomic analyses suggest that the current North African gene pool was mainly influenced by population flow coming from the East that altered the genetic structure of autochthonous Berber populations. Such genetic flow has not been extensively addressed yet using North African populations of Middle-eastern origin as reference. To discern the Middle-eastern component in the genetic background of Tunisian Arabs and evaluate the extent of gene flow from the Middle East into North African autochthonous Berber populations. This study has examined 113 Tunisians of well-known Arabian origin from Kairouan region, using 15 autosomal Short Tandem Repeats (STRs) loci. No deviations from Hardy-Weinberg equilibrium were observed and all loci presented high levels of heterozygosity. Principal coordinate and STRUCTURE analyses were consistent in clustering together North African and Middle Eastern populations, likely reflecting the recent gene flow from the East dating back to the Arab conquest period. This demographic migration and the Arabisation process that submerged the original Berber language and customs seems to have be accompanied by substantial gene flow and genetic admixture. This study represents an additional step to obtain a comprehensive understanding of the complex demographic history of North African populations.

  12. Extremely low genetic diversity across mangrove taxa reflects past sea level changes and hints at poor future responses.

    Science.gov (United States)

    Guo, Zixiao; Li, Xinnian; He, Ziwen; Yang, Yuchen; Wang, Wenqing; Zhong, Cairong; Greenberg, Anthony J; Wu, Chung-I; Duke, Norman C; Shi, Suhua

    2018-04-01

    The projected increases in sea levels are expected to affect coastal ecosystems. Tropical communities, anchored by mangrove trees and having experienced frequent past sea level changes, appear to be vibrant at present. However, any optimism about the resilience of these ecosystems is premature because the impact of past climate events may not be reflected in the current abundance. To assess the impact of historical sea level changes, we conducted an extensive genetic diversity survey on the Indo-Malayan coast, a hotspot with a large global mangrove distribution. A survey of 26 populations in six species reveals extremely low genome-wide nucleotide diversity and hence very small effective population sizes (N e ) in all populations. Whole-genome sequencing of three mangrove species further shows the decline in N e to be strongly associated with the speed of past changes in sea level. We also used a recent series of flooding events in Yalong Bay, southern China, to test the robustness of mangroves to sea level changes in relation to their genetic diversity. The events resulted in the death of half of the mangrove trees in this area. Significantly, less genetically diverse mangrove species suffered much greater destruction. The dieback was accompanied by a drastic reduction in local invertebrate biodiversity. We thus predict that tropical coastal communities will be seriously endangered as the global sea level rises. Well-planned coastal development near mangrove forests will be essential to avert this crisis. © 2017 John Wiley & Sons Ltd.

  13. Paralog-divergent Features May Help Reduce Off-target Effects of Drugs: Hints from Glucagon Subfamily Analysis

    Directory of Open Access Journals (Sweden)

    Zhining Sa

    2017-08-01

    Full Text Available Side effects from targeted drugs remain a serious concern. One reason is the nonselective binding of a drug to unintended proteins such as its paralogs, which are highly homologous in sequences and have similar structures and drug-binding pockets. To identify targetable differences between paralogs, we analyzed two types (type-I and type-II of functional divergence between two paralogs in the known target protein receptor family G-protein coupled receptors (GPCRs at the amino acid level. Paralogous protein receptors in glucagon-like subfamily, glucagon receptor (GCGR and glucagon-like peptide-1 receptor (GLP-1R, exhibit divergence in ligands and are clinically validated drug targets for type 2 diabetes. Our data showed that type-II amino acids were significantly enriched in the binding sites of antagonist MK-0893 to GCGR, which had a radical shift in physicochemical properties between GCGR and GLP-1R. We also examined the role of type-I amino acids between GCGR and GLP-1R. The divergent features between GCGR and GLP-1R paralogs may be helpful in their discrimination, thus enabling the identification of binding sites to reduce undesirable side effects and increase the target specificity of drugs.

  14. PROFIBUS-DP. Fundamentals and hints for users; PROFIBUS-DP. Grundlagen, Tips und Tricks fuer Anwender

    Energy Technology Data Exchange (ETDEWEB)

    Popp, M.

    1998-04-01

    PROFIBUS-DP is one of the most common field buses for industrial communication. The author provides competent help in using this technology. He describes 32 of the most common errors found in certification tests and shows how they can be remedies. Fundamentals and enhancements of PROFIBUS-DP are presented. PROFIBUS-DP telegrams for data interpretation are discussed at length, as are extensive GSD files. Particular emphasis is given to the projecting and commissioning of a system and practical guides for installation. (orig.) [Deutsch] PROFIBUS-DP gehoert zu den am haeufigsten eingesetzten Feldbussen fuer die industrielle Kommunikation. Der Autor bietet in diesem umfassenden Werk kompetente Unterstuetzung bei der Anwendung dieser Feldbustechnik. Es werden 32 der haeufigsten Fehler, die bei Zertifizierungstests festgestellt wurden, beschrieben und Wege zu ihrer Behebung dargestellt. Die Grundlagen von PROFIBUS-DP werden erlaeutert und die PROFIBUS-Erweiterungen vorgestellt. PROFIBUS-DP-Telegramme zur Interpretation des Datenverkehrs werden genauso detailliert erklaert wie eine umfangreiche GSD-Datei. Ein besonderer Schwerpunkt ist die Projektierung und Inbetriebnahme einer Anlage und den praxisgerechten Aufbaurichtlinien gewidmet. (orig./GL)

  15. Arukaotus haridus- ja teadussüsteemis : praegu toimuv tundub mõnes valdkonnas absurditeatrina / Mati Hint

    Index Scriptorium Estoniae

    Hint, Mati

    2004-01-01

    Autor avaldab pahameelt Eesti haridus- ja teadussüsteemis toimuva üle, hindamissüsteemi muutmise ning ülikoolides õpetatavate erialade õppekavade ja õppe- ja teadusliku töö taseme rahvusvahelise hindamise kriteeriumide kohta

  16. Factors Influencing Communication with Doctors via the Internet: A Cross-Sectional Analysis of 2014 HINTS Survey.

    Science.gov (United States)

    Jiang, Shaohai; Street, Richard L

    2017-02-01

    Based on Street's (2003) ecological framework of communication in medical encounters, this study examined personal, interpersonal, and media factors that could influence patients' use of the Internet to communicate with doctors. Results from data analysis of responses from the 2014 Health Information National Trends Survey showed that patient activation and ease of Internet access were two positive predictors of online doctor-patient communication. In addition, patients' trust in doctors positively moderated the relationships between patient activation and online doctor-patient communication, and between perceived health status and online doctor-patient communication. Finally, the quality of patients' past experiences communicating with doctors had a positive moderation effect on the association between health information seeking behavior and online doctor-patient communication. Implications and limitations are discussed.

  17. Chlorophyll-a Estimation Around the Antarctica Peninsula Using Satellite Algorithms: Hints from Field Water Leaving Reflectance

    Directory of Open Access Journals (Sweden)

    Chen Zeng

    2016-12-01

    Full Text Available Ocean color remote sensing significantly contributes to our understanding of phytoplankton distribution and abundance and primary productivity in the Southern Ocean (SO. However, the current SO in situ optical database is still insufficient and unevenly distributed. This limits the ability to produce robust and accurate measurements of satellite-based chlorophyll. Based on data collected on cruises around the Antarctica Peninsula (AP on January 2014 and 2016, this research intends to enhance our knowledge of SO water and atmospheric optical characteristics and address satellite algorithm deficiency of ocean color products. We collected high resolution in situ water leaving reflectance (±1 nm band resolution, simultaneous in situ chlorophyll-a concentrations and satellite (MODIS and VIIRS water leaving reflectance. Field samples show that clouds have a great impact on the visible green bands and are difficult to detect because NASA protocols apply the NIR band as a cloud contamination threshold. When compared to global case I water, water around the AP has lower water leaving reflectance and a narrower blue-green band ratio, which explains chlorophyll-a underestimation in high chlorophyll-a regions and overestimation in low chlorophyll-a regions. VIIRS shows higher spatial coverage and detection accuracy than MODIS. After coefficient improvement, VIIRS is able to predict chlorophyll a with 53% accuracy.

  18. Physical activity in young adults: a signal detection analysis of Health Information National Trends Survey (HINTS) 2007 data.

    Science.gov (United States)

    Valle, Carmina G; Tate, Deborah F; Mayer, Deborah K; Allicock, Marlyn; Cai, Jianwen; Campbell, Marci K

    2015-01-01

    Many young adults are insufficiently active to achieve the health benefits of regular physical activity. Using signal detection analysis of data from the 2007 Health Information National Trends Survey, the authors examined distinct subgroups of 18-39 year-old adults who vary in their likelihood of not meeting physical activity recommendations. We randomly split the sample and conducted signal detection analysis on the exploratory half to identify subgroups and interactions among sociodemographic and health communication variables that predicted engaging in less than 150 minutes per week of moderate-intensity physical activity (low physical activity). We compared rates of low physical activity among subgroups with similarly defined subgroups in the validation sample. Overall, 62% of participants did not meet physical activity recommendations. Among 8 subgroups identified, low physical activity rates ranged from 31% to 90%. Predictors of low physical activity were general health, body mass index (BMI), perceived cancer risk, health-related Internet use, and trust in information sources. The least active subgroup (90% low physical activity) included young adults in poor to good health with a BMI of 30.8 or more (obese). The most active subgroup (31% low physical activity) comprised those in very good to excellent health, who used a website to help with diet, weight, or physical activity, and had little to no trust in health information on television. Findings suggest potential intervention communication channels and can inform targeted physical activity interventions for young adults.

  19. Chlorophyll-a Estimation Around the Antarctica Peninsula Using Satellite Algorithms: Hints from Field Water Leaving Reflectance.

    Science.gov (United States)

    Zeng, Chen; Xu, Huiping; Fischer, Andrew M

    2016-12-07

    Ocean color remote sensing significantly contributes to our understanding of phytoplankton distribution and abundance and primary productivity in the Southern Ocean (SO). However, the current SO in situ optical database is still insufficient and unevenly distributed. This limits the ability to produce robust and accurate measurements of satellite-based chlorophyll. Based on data collected on cruises around the Antarctica Peninsula (AP) on January 2014 and 2016, this research intends to enhance our knowledge of SO water and atmospheric optical characteristics and address satellite algorithm deficiency of ocean color products. We collected high resolution in situ water leaving reflectance (±1 nm band resolution), simultaneous in situ chlorophyll-a concentrations and satellite (MODIS and VIIRS) water leaving reflectance. Field samples show that clouds have a great impact on the visible green bands and are difficult to detect because NASA protocols apply the NIR band as a cloud contamination threshold. When compared to global case I water, water around the AP has lower water leaving reflectance and a narrower blue-green band ratio, which explains chlorophyll-a underestimation in high chlorophyll-a regions and overestimation in low chlorophyll-a regions. VIIRS shows higher spatial coverage and detection accuracy than MODIS. After coefficient improvement, VIIRS is able to predict chlorophyll a with 53% accuracy.

  20. Synchrotron FT-IR analyses of microstructured biomineral domains: Hints to the biomineralization processes in freshwater cultured pearls.

    Science.gov (United States)

    Soldati, A. L.; Vicente-Vilas, V.; Gasharova, B.; Jacob, D. E.

    2009-04-01

    Recent investigations in freshwater cultured pearls (bio-carbonate) by micro-Raman spectroscopy (Wehrmeister et al., 2008; Soldati et al., 2008), Scanning Electron Microscopy (SEM) and Transmission Electron Microscopy (TEM) imaging (Jacob et al., 2008) show that the pearl biomineralisation starts with a self assembling process in which an existing gel matrix of amorphous calcium carbonate (ACC) and organic substances reorganizes and conglomerates in small domains; these conglomerates then form prisms and mature nacreous tablets of aragonite or vaterite. Raman spectroscopy shows that the calcium carbonate polymorphs have decreasing luminescence in the order ACC>Vaterite>Aragonite, coinciding with decreasing quantities of S and P (related to the organic matrix) measured by Laser Ablation Inductively Coupled Plasma Mass Spectroscopy (LA-ICP-MS) and Electron Probe Micro Analyzer (EPMA). Although little is known about the process of transformation of the ACC gel into vaterite and aragonite, it is speculated that this probably involves dehydration and change of the accompanying organic matrix. This is also supported by our laboratory FT-IR analysis. However, due to the small size of the areas of ACC (about 10 ?m) and the biogenic crystals an in-situ high spatially resolved IR-method is needed to record how the water content and organic matrix change in the biomineralisation sequence, to understand which processes take place in the self-organization. The beamline IR-1 at the ANKA synchrotron source (Karlsruhe, Germany) was used for this experiment. Freshwater cultured pearls from China cultured in Hyriopsis cumingii mussels by tissue nucleation methods (so-called beadless pearls) as well as by bead implantation methods (aragonite nucleus) were studied. The pearls were cut in half with a diamond-plated saw and polished with diamond paste on a copper plate. Micro-Raman spectroscopy maps (Department of Geosciences, at the Johannes Gutenberg-University, Mainz) were generated to identify and pre-select those pearls containing ACC. Infrared absorption spectra were measured using a Ge ATR objective on 100-200 ?m thin sections and polished pearl sections. Attenuated total reflectance spectroscopy gives the opportunity to measure the infrared absorption in a reflectance mode directly without necessity to apply Kramers-Kronig transformation. The spectral range available is 650-5000 cm-1when using a Ge ATR crystal with the MCT detector at the ANKA-IR microscope and allowed the detection of the ?4 in-plane bending band (around 750 cm-1 in vaterite and 710 cm-1 in aragonite), the ?1 symmetric stretching bands (1070-7085 cm-1 for vaterite4 and 1082-1084 cm-1 in aragonite5), the ?2 out-of-plane bending vibration of the CO3 groups (855 cm-1 for vaterite and 857-877 cm-1 in aragonite) and the ?3 asymmetric stretching (1420-1490 cm-1 in vaterite and 1480 cm-1 in aragonite) respectively (Sato and Masuda, 1969; Yamoto et al., 1974).Water was detected by the presence of the O-H stretching at around 3500 cm-1. Proteins and sugars included in the biogenic carbonates were recognized through the N-H and C-H bands, for example 1717-1575 cm-1 for aspartic acid, 1712-1558 cm-1 for glutamic acid, 1500 to 2000 cm-1 amide I and II (Dauphin et al., 2006). References WEHRMEISTER U., JACOB D.E., SOLDATI A.L., HÄGER T. & HOFMEISTER W. 2007. Vaterite in freshwater cultured pearls from China and Japan. The Journal of Gemmology; 31: 269-276. SOLDATI A.L., JACOB D.E., WEHRMEISTER U.& HOFMEISTER W. 2008. Structural characterization and chemical composition of aragonite and vaterite in freshwater cultured pearls. Mineralogical Magazine 72: 577-590. JACOB, D.E., SOLDATI, A.L., WIRTH, R., HUTH, J., WEHRMEISTER, U. & HOFMEISTER, W. 2008. Nanostructure, composition and mechanisms of bivalve shell growth. Geochimica et Coscmochimica Acta 72: 5401-5415. SATO M. & MATSUDA S. 1969. Structure of vaterite and infrared spectra. Z. Kistalography 129: 405-410. YAMAMOTO A, SHIRO Y & MURATA H. 1974 Optically-active vibrations and elastic constants of calcite and aragonite. Bulletin Chemical Society Japan, 47:265-273. DAUPHIN Y. 2006. Structure and composition of steptal nacreous layer of Nautilus macromphalus L. (Mollusca, Cephalopoda). Zoology 109: 95-95.

  1. Riia Oja : maja läbi kolme korruse ja kahe tänava / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Tallinnas Uuel tänaval asuva eramu sisekujundus. Hoone on ehitatud 19. sajandi lõpul Pikal tänaval asuva elamu pesuköögiks. Sisearhitekt Riia Oja, kes projekteeris ka köögimööbli. vitraažid tegi Kaie Pärn. Renoveerimistöid teostas Hard Restauraator. Riia Oja ja omaniku kommentaarid. Ill.: korruste plaanid, 7 värv. vaadet

  2. The Effect of Hints and Model Answers in a Student-Controlled Problem-Solving Program for Secondary Physics Education

    NARCIS (Netherlands)

    Pol, Henk J.; Harskamp, Egbert G.; Suhre, Cor J. M.; Goedhart, Martin J.

    Many students experience difficulties in solving applied physics problems. Most programs that want students to improve problem-solving skills are concerned with the development of content knowledge. Physhint is an example of a student-controlled computer program that supports students in developing

  3. Nonenzymatic Oligomerization of 3 ',5 '-Cyclic CMP Induced by Proton and UV Irradiation Hints at a Nonfastidious Origin of RNA

    Czech Academy of Sciences Publication Activity Database

    Costanzo, G.; Giorgi, A.; Scipioni, A.; Timperio, A.M.; Mancone, C.; Tripodis, N.; Kapralov, M.; Krasavin, E.; Kruse, Holger; Šponer, Jiří; Šponer, Judit E.; Ranc, V.; Otyepka, M.; Pino, S.; Di Mauro, E.

    2017-01-01

    Roč. 18, č. 15 (2017), s. 1535-1543 ISSN 1439-4227 R&D Projects: GA ČR GA17-05076S Institutional support: RVO:68081707 Keywords : template-directed synthesis * prebiotic chemistry * montmorillonite catalysis Subject RIV: CE - Biochemistry OBOR OECD: Biochemistry and molecular biology Impact factor: 2.847, year: 2016

  4. Breast cancer arising within fibroadenoma: collective analysis of case reports in the literature and hints on treatment policy.

    Science.gov (United States)

    Wu, Yu-Ting; Chen, Shou-Tung; Chen, Chih-Jung; Kuo, Yao-Lung; Tseng, Ling-Ming; Chen, Dar-Ren; Kuo, Shou-Jen; Lai, Hung-Wen

    2014-11-10

    Breast cancer arising within a fibroadenoma (BcaFad) is rare; the rate varies from 0.002% to 0.125% in fibroadenoma specimens. Owing to its rarity, the clinicopathologic feature and treatment principle of BcaFad is still not clear. Therefore, the aim of this study was to perform a collective analysis of case reports in the literature to identify the characteristics and optimal treatment for BcaFad. We analyzed an aggregated sample of 30 patients with BcaFad from case reports in the literature (n=24 cases) and our present study (n=6 cases). We collected and analyzed the clinicopathologic features and prognoses of patients with BcaFad, as well as treatments they received. The patients' mean age at diagnosis was 46.9 years. Twenty BcaFad patients (66.7%) received breast-conserving surgery (BCS), and nine other patients (30.0%) were treated with mastectomy. The rate of lymph node metastasis in BcaFad patients was 23.8%. The breakdown of the histological types of BcaFad was invasive ductal carcinoma (53.3%), followed by ductal carcinoma in situ (23.3%), lobular carcinoma in situ (16.7%) and invasive lobular carcinoma (13.3%). More than half of patients with positive hormone receptor status received hormone therapy. Most BcaFad patients with lymph node metastases received chemotherapy, and 20.0% of BcaFad patients treated with BCS received further radiotherapy. Only one patient had recurrence after surgery, and another had lung metastasis when diagnosed with BcaFad. Most BcaFad patients could be managed by BCS. Adjuvant radiotherapy could be performed, but was not mandatory. Chemotherapy should be considered as a treatment option in the presence of lymph node metastasis.

  5. Regional climate pattern during two millennia estimated from annual tree rings of Yaku cedar trees: a hint for solar variability?

    Science.gov (United States)

    Muraki, Yasushi; Mitsutani, Takumi; Shibata, Shoichi; Kuramata, Syuichi; Masuda, Kimiaki; Nagaya, Kentaro

    2015-02-01

    We analyzed trees that have survived on Yaku island (Yakushima) for 2,000 years. Quite surprisingly, the Fourier and wavelet analyses of the annual growth rate identified 2 cycles of periodicities of 11 and (24 ± 4) years during the Oort, Wolf, Spörer, Maunder, and Dalton minima. The 11-year periodicity originated from solar activity, while the (24 ± 4)-year periodicity may be related to the Pacific Decadal Oscillation (PDO). In particular, we have discovered an 11-year periodicity in the meteorological daylight-hour data from Yakushima in the month of June during 1938 to 2013 and a 24-year periodicity in July. The growth rate of the tree rings may be affected by the variation of the daylight hour.

  6. Galaxy formation in the reionization epoch as hinted by Wide Field Camera 3 observations of the Hubble Ultra Deep Field

    International Nuclear Information System (INIS)

    Yan Haojing; Windhorst, Rogier A.; Cohen, Seth H.; Hathi, Nimish P.; Ryan, Russell E.; O'Connell, Robert W.; McCarthy, Patrick J.

    2010-01-01

    We present a large sample of candidate galaxies at z ∼ 7-10, selected in the Hubble Ultra Deep Field using the new observations of the Wide Field Camera 3 that was recently installed on the Hubble Space Telescope. Our sample is composed of 20 z 850 -dropouts (four new discoveries), 15 Y 105 -dropouts (nine new discoveries) and 20 J 125 -dropouts (all new discoveries). The surface densities of the z 850 -dropouts are close to what was predicted by earlier studies, however, those of the Y 105 - and J 125 -dropouts are quite unexpected. While no Y 105 - or J 125 -dropouts have been found at AB ≤ 28.0 mag, their surface densities seem to increase sharply at fainter levels. While some of these candidates seem to be close to foreground galaxies and thus could possibly be gravitationally lensed, the overall surface densities after excluding such cases are still much higher than what would be expected if the luminosity function does not evolve from z ∼ 7 to 10. Motivated by such steep increases, we tentatively propose a set of Schechter function parameters to describe the luminosity functions at z ∼ 8 and 10. As compared to their counterpart at z ∼ 7, here L * decreases by a factor of ∼ 6.5 and φ * increases by a factor of 17-90. Although such parameters are not yet demanded by the existing observations, they are allowed and seem to agree with the data better than other alternatives. If these luminosity functions are still valid beyond our current detection limit, this would imply a sudden emergence of a large number of low-luminosity galaxies when looking back in time to z ∼ 10, which, while seemingly exotic, would naturally fit in the picture of the cosmic hydrogen reionization. These early galaxies could easily account for the ionizing photon budget required by the reionization, and they would imply that the global star formation rate density might start from a very high value at z ∼ 10, rapidly reach the minimum at z ∼ 7, and start to rise again towards z ∼ 6. In this scenario, the majority of the stellar mass that the universe assembled through the reionization epoch seems still undetected by current observations at z ∼ 6. (research papers)

  7. Media exposure and tobacco product addiction beliefs: Findings from the 2015 Health Information National Trends Survey (HINTS-FDA 2015).

    Science.gov (United States)

    Donaldson, Elisabeth A; Hoffman, Allison C; Zandberg, Izabella; Blake, Kelly D

    2017-09-01

    Addiction beliefs about tobacco use are associated with intentions to use and use of tobacco products. Exposure to information about tobacco products in media sources may affect addiction beliefs. To examine the relationship between media exposure and tobacco product addiction beliefs. A nationally representative sample of US adults (n=3738) from the 2015 National Cancer Institute's Health Information National Trends Survey was used to examine addiction beliefs about cigarettes, cigars, smokeless tobacco, electronic cigarettes, hookah/waterpipe tobacco, and roll-your-own cigarettes. We used logistic regression to examine the relationship between media exposure and addiction beliefs. We defined media exposure by hours exposed, as well as exposure to tobacco use health effects information through media sources including social media. We categorized media sources by whether respondents actively or passively engaged with the source. A majority (60.6% to 87.3%) of respondents believed that cigarettes, cigars, roll-your-own cigarettes and smokeless tobacco are addictive. Less than half of respondents believed that electronic cigarettes or hookah/waterpipes are addictive (45.2% and 49.8%, respectively). Respondents exposed to messages about tobacco use health effects on active media channels (e.g., social media) had greater odds of believing that smokeless tobacco (adjusted odds ratio [AOR]=1.48), hookah/waterpipe (AOR=1.69), and roll-your-own cigarettes (AOR=1.61) are addictive. Respondents exposed to tobacco use health effects messages on passive media channels (e.g., television), had greater odds of believing that cigarettes (AOR=2.76) and electronic cigarettes (AOR=2.12) are addictive. US adult exposure to information about the health effects of tobacco use was associated with addiction beliefs about tobacco products. Published by Elsevier Ltd.

  8. The Emilia 2012 seismic sequence: hints on incipient basement-involved deformation in the foreland of the Northern Apennines (Italy)

    Science.gov (United States)

    Argnani, Andrea; Carannante, Simona; Massa, Marco; D'Alema, Ezio; Lovati, Sara

    2015-04-01

    The deformation front of the Northern Apennines is buried under the sediments of the Po Plain and was formed mainly during the Pliocene. The remarkably arcuate shape of the thrust front contrasts with the linear northwestern trend of the pede-Apennines, where recent deformation is documented by both geological and geodetic evidence. This study presents new geological and seismological data that are used to assess the structural style of the Ferrara Arc, a sector of the Northern Apennine front that was hit by two strong earthquakes on May 20 (MW 6.1) and May 29 (MW 6.0), 2012. The proposed interpretation is based on a dense grid of commercial seismic profiles and exploration wells, and high-quality relocation of ~5,300 earthquakes (the Emilia sequence). The seismicity was used to calibrate new one-dimensional and three-dimensional local Vp and Vs velocity models for the area. On the basis of these new models, the initial sparse hypocenters were then relocated in absolute mode and adjusted using the double-difference relative location algorithm. Seismicity distribution is elongated in the W-NW to E-SE directions, reaching a depth of 10-12 km. The aftershocks of the May 20 mainshock appear to be distributed on a rupture surface that dips ~45° SSW, and the surface projection indicates an area ~10 km wide and 23 km long. The aftershocks of the May 29 second mainshock followed a steep rupture surface that is well constrained within the investigated volume, whereby the surface projection of the blind source indicates an area ~6 km wide and 33 km long. The analysed multichannel seismic profiles highlight the presence of relevant lateral variations in the structural style of the Ferrara folds that developed during the Pliocene and Pleistocene, and also show the occurrence of a Mesozoic extensional fault system in the Ferrara arc, which in places has been seismically reactivated. These geological and seismological observations suggest that the 2012 Emilia earthquakes were related to ruptures along blind fault surfaces that are not part of the Pliocene-Pleistocene structural system, but are instead related to a deeper system that is itself closely related to re-activation of a Mesozoic extensional fault system. The implication is that the Emilia 2012 seismic sequence was related to activation of a new deformation system that has developed since the late Pleistocene and that affects the deeper structural levels within the Adriatic crust. This interpretation has major relevance for the seismotectonic characterization of the Po Plain, because the location and extent of the Ferrara folds, that were formed during the Pliocene-Pleistocene, cannot simply be used to estimate the seismogenic potential of the Ferrara Arc region.

  9. Hint of Universal Law for the Financial Gains of Competitive Sport Teams. The case of Tour de France cycle race.

    Science.gov (United States)

    Ausloos, Marcel

    2017-12-01

    This short note is intended as a "Letter to the Editor" Perspective in order that it serves as a contribution, in view of reaching the physics community caring about rare events and scaling laws and unexpected findings, on a domain of wide interest: sport and money. It is apparent from the data reported and discussed below that the scarcity of such data does not allow to recommend a complex elaboration of an agent based model, - at this time. In some sense, this also means that much data on sport activities is not necessarily given in terms of physics prone materials, but it could be, and would then attract much attention. Nevertheless the findings tie the data to well known scaling laws and physics processes. It is found that a simple scaling law describes the gains of teams in recent bicycle races, like the Tour de France. An analogous case, ranking teams in Formula 1 races, is shown in an Appendix

  10. Stress in School. Some Empirical Hints on the Circadian Cortisol Rhythm of Children in Outdoor and Indoor Classes.

    Science.gov (United States)

    Dettweiler, Ulrich; Becker, Christoph; Auestad, Bjørn H; Simon, Perikles; Kirsch, Peter

    2017-04-30

    This prospective longitudinal survey compared the stress levels of students taught using an outdoor curriculum in a forest, with children in a normal school setting. We were especially interested in the effect outdoor teaching might have on the children's normal diurnal cortisol rhythm. 48 children (mean age = 11.23; standard deviation (SD) = 0.46) were enrolled, with 37 in the intervention group (IG), and 11 in the control group (CG). The intervention consisted of one full school day per week in the forest over the school year. Stress levels were measured in cortisol with three samples of saliva per day. Furthermore, the data allowed for statistical control of physical activity (PA) values. For data analysis, we used a linear mixed-effects model (LMM) with random intercept and general correlation matrix for the within-unit residuals. The LMM yields that IG have expected greater decline of cortisol compared to CG; rate 0.069 µg/L vs. 0.0102 µg/L (log-units/2 h), p = 0.009. PA does not show a statistically significant interaction with cortisol ( p = 0.857), despite being higher in the intervention group ( p child's diurnal rhythm, with a significant decline of cortisol from morning to noon. This effect is constant over the school year. The CG does not show this decline during either measurement day. Further research is needed to fully explain this interesting phenomenon.

  11. Implications of social media use on health information technology engagement: Data from HINTS 4 cycle 3.

    Science.gov (United States)

    Jackson, Devlon N; Chou, Wen-Ying Sylvia; Coa, Kisha I; Oh, April; Hesse, Bradford

    2016-12-01

    Little is known about the association between Internet/social media use and health information technology (HIT) engagement. This study examines patterns of social media use and HIT engagement in the U.S.A. using data from the 2013 Health Information National Trends Survey (N = 3,164). Specifically, predictors of two HIT activities (i.e., communicating with a healthcare provider using the Internet or email and tracking personal health information electronically) are examined. Persons who were females, higher education, non-Hispanic others, having a regular healthcare provider, and ages 35-44 were more likely to participate in HIT activities. After controlling for sociodemographics and health correlates, social media use was significantly associated with HIT engagement. To our knowledge, this is one of the first studies to systematically examine the use and relationships across multiple types of health-related online media.

  12. Akhet Khufu: archaeo-astronomical hints at a common project of the two main pyramids of Giza, Egypt

    OpenAIRE

    Magli, Giulio

    2007-01-01

    The architectural complexes composed by the two main pyramids of Giza together with their temples are investigated from an inter-disciplinary point of view, taking into account their astronomical alignments as well as their relationships with the visible landscape. Combining already known facts together with new clues, the work strongly supports the idea that the two complexes were conceived as parts of a common project.

  13. Effects of layered crust on the coseismic slip inversion and related CFF variations: Hints from the 2012 Emilia Romagna earthquake

    Science.gov (United States)

    Nespoli, Massimo; Belardinelli, Maria E.; Anderlini, Letizia; Bonafede, Maurizio; Pezzo, Giuseppe; Todesco, Micol; Rinaldi, Antonio P.

    2017-12-01

    The 2012 Emilia Romagna (Italy) seismic sequence has been extensively studied given the occurrence of two mainshocks, both temporally and spatially close to each other. The recent literature accounts for several fault models, obtained with different inversion methods and different datasets. Several authors investigated the possibility that the second event was triggered by the first mainshock with elusive results. In this work, we consider all the available InSAR and GPS datasets and two planar fault geometries, which are based on both seismological and geological constraints. We account for a layered, elastic half-space hosting the dislocation and compare the slip distribution resulting from the inversion and the related changes in Coulomb Failure Function (CFF) obtained with both a homogeneous and layered half-space. Finally, we focus on the interaction between the two main events, discriminating the contributions of coseismic and early postseismic slip of the mainshock on the generation of the second event and discuss the spatio-temporal distribution of the seismic sequence. When accounting for both InSAR and GPS geodetic data we are able to reproduce a detailed coseismic slip distribution for the two mainshocks that is in accordance with the overall aftershock seismicity distribution. Furthermore, we see that an elastic medium with depth dependent rigidity better accounts for the lack of the shallow seismicity, amplifying, with respect to the homogeneous case, the mechanical interaction of the two mainshocks.

  14. Some correlations between eight types of malignant neoplasms: A hint from cancer dynamics of 31 European countries in 20 years

    Directory of Open Access Journals (Sweden)

    WenJun Zhang

    2017-09-01

    Full Text Available In present study, the data of standardised death rates of malignant neoplasms per 100000 inhabitants in 31 European countries during 1994-2013 were used to analyze linear correlations between eight types of cancers in terms of induced death rates. The results showed that most pairs of cancers closely correlate to each other. The malignant neoplasm of cervix uteri (women and the malignant neoplasm of trachea, bronchus and lung correlate most closely (r=0.5915, followed by the malignant neoplasms (r=0.4832 of colon, rectosigmoid junction, rectum, anus and anal canal and lymphatic/haematopoietic tissue, the malignant neoplasms (r=-0.483 of stomach, and trachea, bronchus and lung, the malignant neoplasms (r=0.4605 of skin and prostate (men, the malignant neoplasms (r=0.4344 of colon, rectosigmoid junction, rectum, anus and anal canal and trachea, bronchus and lung, etc. These correlations are likely caused by common or adverse environmental, social, medical or even genetic / molecular factors.

  15. Hints of an axion-like particle mixing in the GeV gamma-ray blazar data?

    Energy Technology Data Exchange (ETDEWEB)

    Mena, Olga [IFIC, Universidad de Valencia-CSIC, E-46071, Valencia (Spain); Razzaque, Soebur, E-mail: omena@ific.uv.es, E-mail: srazzaque@uj.ac.za [Department of Physics, University of Johannesburg, PO Box 524, Auckland Park 2006 (South Africa)

    2013-11-01

    Axion-Like Particles (ALPs), if exist in nature, are expected to mix with photons in the presence of an external magnetic field. The energy range of photons which undergo strong mixing with ALPs depends on the ALP mass, on its coupling with photons as well as on the external magnetic field and particle density configurations. Recent observations of blazars by the Fermi Gamma-Ray Space Telescope in the 0.1–300 GeV energy range show a break in their spectra in the 1–10 GeV range. We have modeled this spectral feature for the flat-spectrum radio quasar 3C454.3 during its November 2010 outburst, assuming that a significant fraction of the gamma rays convert to ALPs in the large scale jet of this blazar. Using theoretically motivated models for the magnetic field and particle density configurations in the kiloparsec scale jet, outside the broad-line region, we find an ALP mass m{sub a} ∼ (1−3)⋅10{sup −7} eV and coupling g{sub aγ} ∼ (1−3)⋅10{sup −10} GeV{sup −1} after performing an illustrative statistical analysis of spectral data in four different epochs of emission. The precise values of m{sub a} and g{sub aγ} depend weakly on the assumed particle density configuration and are consistent with the current experimental bounds on these quantities. We apply this method and ALP parameters found from fitting 3C454.3 data to another flat-spectrum radio quasar PKS1222+216 (4C+21.35) data up to 400 GeV, as a consistency check, and found good fit. We find that the ALP-photon mixing effect on the GeV spectra may not be washed out for any reasonable estimate of the magnetic field in the intergalactic media.

  16. The hint protocol: Using a broadcast method to enable ID-free data transmission for dense IoT devices

    OpenAIRE

    Ren, Yi; Wu, Ren-Jie; Tseng, Yu-Chee

    2017-01-01

    IoT (Internet of Things) has attracted a lot of attention recently. IoT devices need to report their data or status to base stations at various frequencies. The IoT communications observed by a base station normally exhibit the following characteristics: (1) massively connected, (2) lightly loaded per packet, and (3) periodical or at least mostly predictable. The current design principals of communication networks, when applied to IoT scenarios, however, do not fit well to these requirements....

  17. Give me a hint: An ID-free small data transmission protocol for dense IoT devices

    OpenAIRE

    Ren, Yi; Wu, Ren-Jie; Huang, Teng-Wei; Tseng, Yu-Chee

    2017-01-01

    IoT (Internet of Things) has attracted a lot of attention recently. IoT devices need to report their data or status to base stations at various frequencies. The IoT communications observed by a base station normally exhibit the following characteristics: (1) massively connected, (2) lightly loaded per packet, and (3) periodical or at least mostly predictable. The current design principals of communication networks, when applied to IoT scenarios, however, do not fit well to these requirements....

  18. Changes in optical characteristics of surface microlayers hint to photochemically and microbially-mediated DOM turnover in the upwelling region off Peru

    Science.gov (United States)

    Galgani, L.; Engel, A.

    2015-12-01

    The coastal upwelling system off Peru is characterized by high biological activity and a pronounced subsurface oxygen minimum zone, as well as associated emissions of atmospheric trace gases such as N2O, CH4 and CO2. During the Meteor (M91) cruise to the Peruvian upwelling system in 2012, we investigated the composition of the sea-surface microlayer (SML), the oceanic uppermost boundary directly subject to high solar radiation, often enriched in specific organic compounds of biological origin like Chromophoric Dissolved Organic Matter (CDOM) and marine gels. In the SML, the continuous photochemical and microbial recycling of organic matter may strongly influence gas exchange between marine systems and the atmosphere. In order to understand organic matter cycling in surface films, we analyzed SML and underlying water samples at 38 stations determining DOC concentration, amino acid composition, marine gels, CDOM and bacterial and phytoplankton abundance as indicators of photochemical and microbial alteration processes. CDOM composition was characterized by spectral slope (S) values and Excitation-Emission Matrix fluorescence (EEMs), which allow to track changes in molecular weight (MW) of DOM, and to determine potential DOM sources and sinks. We identified five fluorescent components of the CDOM pool, of which two had excitation/emission characteristics of protein-like fluorophores and were highly enriched in the SML. CDOM composition and changes in spectral slope properties suggested a local microbial release of HMW DOM directly in the SML as a response to light exposure in this extreme environment. Our results suggest that microbial and photochemical processes play an important role for the production, alteration and loss of optically active substances in the SML.

  19. Changes in optical characteristics of surface microlayers in the Peruvian upwelling region hint to photochemically and microbially-mediated DOM turnover

    Science.gov (United States)

    Engel, A.; Galgani, L.

    2016-02-01

    The coastal upwelling system off Peru is characterized by high biological activity and associated subsurface oxygen minimum zone, leading to an enhanced emission of atmospheric trace gases. High biological productivity in the water column may promote the establishment of enriched organic surface films, key environments for processes regulating gas fluxes across the water-air interface. During M91 cruise to the Peruvian upwelling, we focused our attention on the composition of the sea-surface microlayer (SML), the oceanic uppermost boundary directly subject to high solar radiation, often enriched in specific organic compounds of biological origin like Chromophoric Dissolved Organic Matter (CDOM) and marine gels. In the SML, the continuous photochemical and microbial recycling of organic matter may strongly influence gas exchange between marine systems and the atmosphere. In order to understand organic matter cycling in surface films, we analyzed SML and underlying water samples in 38 stations determining DOC concentrations, amino acids composition, marine gels, CDOM and bacterial abundance as indicators of photochemical and microbial alteration processes. CDOM composition was characterized by spectral slopes (S) values and Excitation-Emission Matrix fluorescence (EEMs), which allow to track changes in molecular weight (MW) of DOM, and to determine potential DOM sources. Profound changes in spectral slope properties were observed suggesting smaller MW CDOM in the SML compared to underlying water. Microbial and photochemical degradation are likely the main drivers for organic matter cycling in the top layer of the ocean. Consequences on the formation of inorganic and organic species highly relevant for air-sea gas exchange and for climate dynamics will be discussed.

  20. Comparative expression profiling of AtRAD5B and AtNDL1: Hints towards a role in G protein mediated signaling.

    Science.gov (United States)

    Khatri, Nisha; Singh, Swati; Hakim, Nasmeen; Mudgil, Yashwanti

    2017-11-01

    Arabidopsis AtRAD5B encodes for a putative helicase of the class SWItch/Sucrose Non-Fermentable (SWI/SNF) ATPases. We identified AtRAD5B as an interactor of N-MYC DOWNREGULATED-LIKE1 (AtNDL1) in a yeast two-hybrid screen. AtNDL1 is a G protein signaling component which regulates auxin transport and gradients together with GTP binding protein beta 1 (AGB1). Auxin gradients are known to recruit SWI/SNF remodeling complexes to the chromatin and regulate expression of genes involved in flower and leaf formation. In current study, a comparative spatial and temporal co-expression/localization analysis of AtNDL1, AGB1 with AtRAD5B was carried out in order to explore the possibility of their coexistence in a common signaling network. Translational fusion (GUS) of AtNDL1 and AtRAD5B in seedlings and reproductive organs revealed that both shared similar expression patterns with the highest expression observed in male reproductive organs. Moreover, they shared similar domains of localization in roots, suggesting their potential functioning together in reproductive and root development processes. This study predicts the existence of a signaling network involving AtNDL1, AGB1 with AtRAD5B. Copyright © 2017 Elsevier B.V. All rights reserved.

  1. The 2012-2016 eruptive cycle at Copahue volcano (Argentina) versus the peripheral gas manifestations: hints from the chemical and isotopic features of fumarolic fluids

    Science.gov (United States)

    Tassi, F.; Agusto, M.; Lamberti, C.; Caselli, A. T.; Pecoraino, G.; Caponi, C.; Szentiványi, J.; Venturi, S.; Vaselli, O.

    2017-10-01

    This study presents the chemical and isotopic compositions of hydrothermal gases from fumaroles discharging around Copahue volcano (Argentina). Gas samples, including those from two fumaroles at the active summit crater, were collected during 13 surveys carried out by different research teams from 1976 to February 2016. The time-series of H2, CO and light hydrocarbons showed episodic increases related to the main events of the last eruptive cycle that started on 19 July 2012. Concentration peaks were likely caused by enhanced input of hot magmatic fluids affecting the hydrothermal reservoir. These data contrast with the temporal variations shown by Rc/ Ra and δ13C-CO2 values in 2012-2014, which indicated an increasing input from a crustal fluid source. In 2015-2016, however, these isotopic parameters showed opposite trends; their composition became closer to that of the two summit fumaroles, which possibly corresponds to that of the deep magmatic-related end-member. The delayed and reduced compositional changes in the peripheral hydrothermal fluid discharge in response to the 2012-2016 eruptive events suggest that geochemical surveys of these emissions are unlikely to provide premonitory signals of volcanic unrest if the volcanic activity remains centered in the main crater. Instead, an instrument which is able to provide measurements of volcanic gases in the air (e.g. MultiGAS) may be used to detect changes at the summit crater. Otherwise, monitoring of seismic activity and ground deformation, as well as the periodic measurement of the chemistry of the water in the Rio Agrio, which is fed by thermal discharge from the summit crater, seem to represent the most reliable means of monitoring at Copahue. However, the relative compositional stability of the hydrothermal reservoir is a great advantage in terms of geothermal resource exploitation and could encourage new investments in the Copahue geothermal project which was abandoned in the 1990s.

  2. A new look inside planetary nebula LoTr 5: a long-period binary with hints of a possible third component

    Science.gov (United States)

    Aller, A.; Lillo-Box, J.; Vučković, M.; Van Winckel, H.; Jones, D.; Montesinos, B.; Zorotovic, M.; Miranda, L. F.

    2018-05-01

    LoTr 5 is a planetary nebula with an unusual long-period binary central star. As far as we know, the pair consists of a rapidly rotating G-type star and a hot star, which is responsible for the ionization of the nebula. The rotation period of the G-type star is 5.95 d and the orbital period of the binary is now known to be ˜2700 d, one of the longest in central star of planetary nebulae. The spectrum of the G central star shows a complex H α double-peaked profile which varies with very short time-scales, also reported in other central stars of planetary nebulae and whose origin is still unknown. We present new radial velocity observations of the central star which allow us to confirm the orbital period for the long-period binary and discuss the possibility of a third component in the system at ˜129 d to the G star. This is complemented with the analysis of archival light curves from Super Wide Angle Search for Planets, All Sky Automated Survey, and Optical Monitoring Camera. From the spectral fitting of the G-type star, we obtain an effective temperature of Teff = 5410 ± 250 K and surface gravity of log g = 2.7 ± 0.5, consistent with both giant and subgiant stars. We also present a detailed analysis of the H α double-peaked profile and conclude that it does not present correlation with the rotation period and that the presence of an accretion disc via Roche lobe overflow is unlikely.

  3. Exploring the predictive value of the evoked potentials score in MS within an appropriate patient population: a hint for an early identification of benign MS?

    Directory of Open Access Journals (Sweden)

    Margaritella Nicolò

    2012-08-01

    Full Text Available Abstract Background The prognostic value of evoked potentials (EPs in multiple sclerosis (MS has not been fully established. The correlations between the Expanded Disability Status Scale (EDSS at First Neurological Evaluation (FNE and the duration of the disease, as well as between EDSS and EPs, have influenced the outcome of most previous studies. To overcome this confounding relations, we propose to test the prognostic value of EPs within an appropriate patient population which should be based on patients with low EDSS at FNE and short disease duration. Methods We retrospectively selected a sample of 143 early relapsing remitting MS (RRMS patients with an EDSS Results The Evoked Potentials score (EP score and the Time to EDSS 2.0 (TT2 were the best predictors of worsening in our sample (Odds Ratio 1.10 and 0.82 respectively, p=0.001. Low EP score (below 15–20 points, short TT2 (lower than 3–5 years and their interaction resulted to be the most useful for the identification of worsening patterns. Moreover, in patients with an EP score at FNE below 6 points and a TT2 greater than 3 years the probability of worsening was 10% after 4–5 years and rapidly decreased thereafter. Conclusions In an appropriate population of early RRMS patients, the EP score at FNE is a good predictor of disability at low values as well as in combination with a rapid buildup of disability. Interestingly, an EP score at FNE under the median together with a clinical stability lasting more than 3 years turned out to be a protective pattern. This finding may contribute to an early identification of benign patients, well before the term required to diagnose Benign MS (BMS.

  4. The human interactome knowledge base (hint-kb): An integrative human protein interaction database enriched with predicted protein–protein interaction scores using a novel hybrid technique

    KAUST Repository

    Theofilatos, Konstantinos A.; Dimitrakopoulos, Christos M.; Likothanassis, Spiridon D.; Kleftogiannis, Dimitrios A.; Moschopoulos, Charalampos N.; Alexakos, Christos; Papadimitriou, Stergios; Mavroudi, Seferina P.

    2013-01-01

    Proteins are the functional components of many cellular processes and the identification of their physical protein–protein interactions (PPIs) is an area of mature academic research. Various databases have been developed containing information about

  5. Tüüne-Kristin & Urmo Vaikla : "Oleme mõlemad friigid. Kaitseme oma nägemust mõistliku ajalimiidini" / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Tüüne-Kristin ja Urmo Vaikla interjööri olulistest osadest, harmooniast sisekujunduses, sellest, mida peaks kodu omanikule pakkuma jm. T.-K. ja U. Vaiklast, esinemised näitustel, olulisemate kujundatud ühiskondlike ruumide nimistu, omistatud preemia. 1992. aastast töötavad mõlemad Vaikla Stuudios. Ill.: värv. foto T.-K. ja U. Vaiklast

  6. Examining the Role of Ideological and Political Education on University Students' Civic Perceptions and Civic Participation in Mainland China: Some Hints from Contemporary Citizenship Theory

    Science.gov (United States)

    Zhang, Chong; Fagan, Catherine

    2016-01-01

    A long existing compulsive curriculum of ideological and political education is employed by the Chinese government to promote citizenship education among Chinese university students. This article builds on the findings of a mixed-methods research that examined the role of ideological and political education on university students' civic…

  7. Cesium accumulation by bacterium Thermus sp.TibetanG7: hints for biomineralization of cesiumbearing geyserite in hot springs in Tibet, China

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The bacterium Thermus sp. TibetanG7, isolated from hot springs in Tibet, China, was examined for the ability to accumulate cesium from solutions. Environmental conditions were simulated and the effects of pH, K+, Na+ and K+-regimes were then studied to determine the possible role of the bacterium in the formation of cesium-bearing geyserite around these hot springs. In despite of the inhibition of K+ and Na+, the bacterium Thermus sp. TibetanG7 revealed noticeable accumulation of cesium from solutions, with maximum accumulations of 53.49 and 40.41 μmol Cesium/g cell dry weight in Na+ and K+ inhibition experiments, respectively. The accumulation of cesium by this microorganism is rapid, with 40%―50% accumulated within the first 5 min. K+-deficient cells showed a much higher capacity of cesium accumulation compared with K+-sufficient cells. It is evident that the bacteria within the genus thermus play a significant role in the cesium assembly. The formation of cesium-bearing geyserite is also considered.

  8. HINTW, a W-chromosome HINT gene in chick, is expressed ubiquitously and is a robust female cell marker applicable in intraspecific chimera studies.

    Science.gov (United States)

    Nagai, Hiroki; Sezaki, Maiko; Bertocchini, Federica; Fukuda, Kimiko; Sheng, Guojun

    2014-05-01

    Grafting and transplantation experiments in embryology require proper distinction between host and donor tissues. For the avian model this has traditionally been achieved by using two closely related species (e.g., chick and quail) followed by species-specific antibody staining. Here, we show that an in situ hybridization probe against the HINTW gene is a robust and reliable marker for female-derived chicken cells. At all pre-circulation stages tested, all cells in female embryos, independently confirmed by PCR analysis, were strongly positive for HINTW, whereas all male embryos were negative. This probe is broadly applicable in intra-specific chick/chick chimera studies, and as a proof of principle, we utilized this probe to detect female cells in three experimental settings: (1) to mark female donor cells in a node transplantation assay; (2) to distinguish female cells in male/female twins generated by the Cornish pasty culture; and (3) to detect female half of the embryo in artificially generated bilateral gynandromorphs. A rapid, PCR based pre-screening step increases the efficiency of obtaining desired donor/host sex combination from 25% to 100%. For most avian chimera studies, this female-specific in situ probe is a low cost alternative to the commonly used QCPN antibody and to ubiquitous-GFP chicken strains which are not widely available to the research community. © 2014 Wiley Periodicals, Inc.

  9. The Run Control System and the Central Hint and Information Processor of the Data Acquisition System of the ATLAS Experiment at the LHC

    CERN Document Server

    Anders, G; The ATLAS collaboration; Lehmann Miotto, G; Magnoni, L

    2014-01-01

    The Trigger and Data Acquisition (TDAQ) system of the ATLAS detector is composed of a large number of distributed hardware and software components (about 3000 machines and more than 15000 concurrent processes at the end of LHC’s Run I) which in a coordinated manner provide the data-taking functionality of the overall system. The Run Control (RC) system steers the data acquisition by starting and stopping processes and by carrying all data-taking elements through well-defined states in a coherent way (finite state machine pattern). The RC is organized as a hierarchical tree (run control tree) of run controllers following the functional de-composition into systems and sub-systems of the ATLAS detector. During the LHC Long Shutdown 1 (LS1) the RC has been completely re-designed and re-implemented in order to better fulfill the new requirements which emerged during the LHC Run 1 and were not foreseen during the initial design phase, and in order to improve the error management and recovery mechanisms. Indeed gi...

  10. Changes in optical characteristics of surface microlayers hint to photochemically and microbially mediated DOM turnover in the upwelling region off the coast of Peru

    Science.gov (United States)

    Galgani, Luisa; Engel, Anja

    2016-04-01

    The coastal upwelling system off the coast of Peru is characterized by high biological activity and a pronounced subsurface oxygen minimum zone, as well as associated emissions of atmospheric trace gases such as N2O, CH4 and CO2. From 3 to 23 December 2012, R/V Meteor (M91) cruise took place in the Peruvian upwelling system between 4.59 and 15.4° S, and 82.0 to 77.5° W. During M91 we investigated the composition of the sea-surface microlayer (SML), the oceanic uppermost boundary directly subject to high solar radiation, often enriched in specific organic compounds of biological origin like chromophoric dissolved organic matter (CDOM) and marine gels. In the SML, the continuous photochemical and microbial recycling of organic matter may strongly influence gas exchange between marine systems and the atmosphere. We analyzed SML and underlying water (ULW) samples at 38 stations focusing on CDOM spectral characteristics as indicator of photochemical and microbial alteration processes. CDOM composition was characterized by spectral slope (S) values and excitation-emission matrix fluorescence (EEMs), which allow us to track changes in molecular weight (MW) of DOM, and to determine potential DOM sources and sinks. Spectral slope S varied between 0.012 to 0.043 nm-1 and was quite similar between SML and ULW, with no significant differences between the two compartments. Higher S values were observed in the ULW of the southern stations below 15° S. By EEMs, we identified five fluorescent components (F1-5) of the CDOM pool, of which two had excitation/emission characteristics of amino-acid-like fluorophores (F1, F4) and were highly enriched in the SML, with a median ratio SML : ULW of 1.5 for both fluorophores. In the study region, values for CDOM absorption ranged from 0.07 to 1.47 m-1. CDOM was generally highly concentrated in the SML, with a median enrichment with respect to the ULW of 1.2. CDOM composition and changes in spectral slope properties suggested a local microbial release of DOM directly in the SML as a response to light exposure in this extreme environment. In a conceptual model of the sources and modifications of optically active DOM in the SML and underlying seawater (ULW), we describe processes we think may take place (Fig. 1); the production of CDOM of higher MW by microbial release through growth, exudation and lysis in the euphotic zone, includes the identified fluorophores (F1, F2, F3, F4, F5). Specific amino-acid-like fluorophores (F1, F4) accumulate in the SML with respect to the ULW, as photochemistry may enhance microbial CDOM release by (a) photoprotection mechanisms and (b) cell-lysis processes. Microbial and photochemical degradation are potential sinks of the amino-acid-like fluorophores (F1, F4), and potential sources of reworked and more refractory humic-like components (F2, F3, F5). In the highly productive upwelling region along the Peruvian coast, the interplay of microbial and photochemical processes controls the enrichment of amino-acid-like CDOM in the SML. We discuss potential implications for air-sea gas exchange in this area.

  11. A three-dimensional morphometric analysis of upper forelimb morphology in the enigmatic tapir (Perissodactyla: Tapirus) hints at subtle variations in locomotor ecology.

    Science.gov (United States)

    MacLaren, Jamie A; Nauwelaerts, Sandra

    2016-11-01

    Forelimb morphology is an indicator for terrestrial locomotor ecology. The limb morphology of the enigmatic tapir (Perissodactyla: Tapirus) has often been compared to that of basal perissodactyls, despite the lack of quantitative studies comparing forelimb variation in modern tapirs. Here, we present a quantitative assessment of tapir upper forelimb osteology using three-dimensional geometric morphometrics to test whether the four modern tapir species are monomorphic in their forelimb skeleton. The shape of the upper forelimb bones across four species (T. indicus; T. bairdii; T. terrestris; T. pinchaque) was investigated. Bones were laser scanned to capture surface morphology and 3D landmark analysis was used to quantify shape. Discriminant function analyses were performed to reveal features which could be used for interspecific discrimination. Overall our results show that the appendicular skeleton contains notable interspecific differences. We demonstrate that upper forelimb bones can be used to discriminate between species (>91% accuracy), with the scapula proving the most diagnostic bone (100% accuracy). Features that most successfully discriminate between the four species include the placement of the cranial angle of the scapula, depth of the humeral condyle, and the caudal deflection of the olecranon. Previous studies comparing the limbs of T. indicus and T. terrestris are corroborated by our quantitative findings. Moreover, the mountain tapir T. pinchaque consistently exhibited the greatest divergence in morphology from the other three species. Despite previous studies describing tapirs as functionally mediportal in their locomotor style, we find osteological evidence suggesting a spectrum of locomotor adaptations in the tapirs. We conclude that modern tapir forelimbs are neither monomorphic nor are tapirs as conserved in their locomotor habits as previously described. J. Morphol. 277:1469-1485, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  12. Frequent induction of chromosomal aberrations in in vivo skin fibroblasts after allogeneic stem cell transplantation: hints to chromosomal instability after irradiation

    International Nuclear Information System (INIS)

    Massenkeil, G.; Zschieschang, P.; Thiel, G.; Hemmati, P. G.; Budach, V.; Dörken, B.; Pross, J.; Arnold, R.

    2015-01-01

    Total body irradiation (TBI) has been part of standard conditioning regimens before allogeneic stem cell transplantation for many years. Its effect on normal tissue in these patients has not been studied extensively. We studied the in vivo cytogenetic effects of TBI and high-dose chemotherapy on skin fibroblasts from 35 allogeneic stem cell transplantation (SCT) patients. Biopsies were obtained prospectively (n = 18 patients) before, 3 and 12 months after allogeneic SCT and retrospectively (n = 17 patients) 23–65 months after SCT for G-banded chromosome analysis. Chromosomal aberrations were detected in 2/18 patients (11 %) before allogeneic SCT, in 12/13 patients (92 %) after 3 months, in all patients after 12 months and in all patients in the retrospective group after allogeneic SCT. The percentage of aberrant cells was significantly higher at all times after allogeneic SCT compared to baseline analysis. Reciprocal translocations were the most common aberrations, but all other types of stable, structural chromosomal aberrations were also observed. Clonal aberrations were observed, but only in three cases they were detected in independently cultured flasks. A tendency to non-random clustering throughout the genome was observed. The percentage of aberrant cells was not different between patients with and without secondary malignancies in this study group. High-dose chemotherapy and TBI leads to severe chromosomal damage in skin fibroblasts of patients after SCT. Our long-term data suggest that this damage increases with time, possibly due to in vivo radiation-induced chromosomal instability

  13. Human mtDNA hypervariable regions, HVR I and II, hint at deep common maternal founder and subsequent maternal gene flow in Indian population groups.

    Science.gov (United States)

    Sharma, Swarkar; Saha, Anjana; Rai, Ekta; Bhat, Audesh; Bamezai, Ramesh

    2005-01-01

    We have analysed the hypervariable regions (HVR I and II) of human mitochondrial DNA (mtDNA) in individuals from Uttar Pradesh (UP), Bihar (BI) and Punjab (PUNJ), belonging to the Indo-European linguistic group, and from South India (SI), that have their linguistic roots in Dravidian language. Our analysis revealed the presence of known and novel mutations in both hypervariable regions in the studied population groups. Median joining network analyses based on mtDNA showed extensive overlap in mtDNA lineages despite the extensive cultural and linguistic diversity. MDS plot analysis based on Fst distances suggested increased maternal genetic proximity for the studied population groups compared with other world populations. Mismatch distribution curves, respective neighbour joining trees and other statistical analyses showed that there were significant expansions. The study revealed an ancient common ancestry for the studied population groups, most probably through common founder female lineage(s), and also indicated that human migrations occurred (maybe across and within the Indian subcontinent) even after the initial phase of female migration to India.

  14. Hint of a Universal Law for the Financial Gains of Competitive Sport Teams. The Case of Tour de France Cycle Race

    Directory of Open Access Journals (Sweden)

    Marcel Ausloos

    2017-12-01

    Full Text Available This short note is intended as a “Letter to the Editor” Perspective in order that it serves as a contribution, in view of reaching the physics community caring about rare events and scaling laws and unexpected findings, on a domain of wide interest: sport and money. It is apparent from the data reported and discussed below that the scarcity of such data does not allow to recommend a complex elaboration of an agent based model,—at this time. In some sense, this also means that much data on sport activities is not necessarily given in terms of physics prone materials, but it could be, and would then attract much attention. Nevertheless the findings tie the data to well-known scaling laws and physics processes. It is found that a simple scaling law describes the gains of teams in recent bicycle races, like the Tour de France. An analogous case, ranking teams in Formula 1 races, is shown in an Appendix.

  15. The role of insulin C-peptide in the coevolution analyses of the insulin signaling pathway: a hint for its functions.

    Directory of Open Access Journals (Sweden)

    Shuai Wang

    Full Text Available As the linker between the A chain and B chain of proinsulin, C-peptide displays high variability in length and amino acid composition, and has been considered as an inert byproduct of insulin synthesis and processing for many years. Recent studies have suggested that C-peptide can act as a bioactive hormone, exerting various biological effects on the pathophysiology and treatment of diabetes. In this study, we analyzed the coevolution of insulin molecules among vertebrates, aiming at exploring the evolutionary characteristics of insulin molecule, especially the C-peptide. We also calculated the correlations of evolutionary rates between the insulin and the insulin receptor (IR sequences as well as the domain-domain pairs of the ligand and receptor by the mirrortree method. The results revealed distinctive features of C-peptide in insulin intramolecular coevolution and correlated residue substitutions, which partly supported the idea that C-peptide can act as a bioactive hormone, with significant sequence features, as well as a linker assisting the formation of mature insulin during synthesis. Interestingly, the evolution of C-peptide exerted the highest correlation with that of the insulin receptor and its ligand binding domain (LBD, implying a potential relationship with the insulin signaling pathway.

  16. Hints of supernova debris deposition on the lunar surface: {sup 60}Fe and {sup 53}Mn measurements by means of accelerator mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Fimiani, Leticia; Faestermann, Thomas; Gomez Guzman, Jose Manuel; Hain, Karin; Korschinek, Gunther; Ludwig, Peter [Physik Department, Technische Universitaet Muenchen, Garching (Germany); Herzog, Gregory; Ligon, Bret; Park, Jisun [Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ (United States); Rugel, Georg [Forschungszentrum Dresden Rossendorf, Dresden (Germany)

    2013-07-01

    The enhanced concentration of {sup 60}Fe in a deep ocean ferro-manganese crust about (2.1±0.4) Myr old (Fitoussi et al., PRL 101, 121101 (2008)), suggests that one or more supernova (SN) explosions occurred in the vicinity of the Solar System. That observation was only possible with the ultra sensitive Accelerator Mass Spectrometry (AMS) technique at the Maier-Leibnitz-Laboratorium in Munich, where we are able to measure concentrations of {sup 60}Fe/Fe down to a level of 10{sup -16}. Because of its lacking atmosphere and negligible sedimentation rate, the Lunar surface is an excellent quantitative reservoir for SN debris. We searched for live {sup 60}Fe and {sup 53}Mn in samples from 3 Apollo missions. {sup 53}Mn is, similar as {sup 26}Al and {sup 60}Fe, a tool to trace nucleosynthesis activities. It is formed primarily during the explosive silicon-burning of the inner shells of SNe via {sup 53}Fe which β-decays to {sup 53}Mn with an 8.51 min half-life. Samples where we found an enhanced {sup 60}Fe concentration showed also an enhancement of {sup 53}Mn. If confirmed, this could be the first detection of live {sup 53}Mn originating from nucleosynthesis.

  17. La Cruzada de los Niños: Memoria, Actualidad y Guiños Históricos The Children's Crusade: Memory, Present Times and Historical Hints

    Directory of Open Access Journals (Sweden)

    Patricio Rodríguez-Plaza

    2010-12-01

    Full Text Available El presente texto se ubica en el supuesto lugar de un espectador ordinario, escudriña críticamente en las problemáticas que expresa y expone la obra La cruzada de los niños, menos desde el texto dramático que desde las dimensiones espectaculares que dotan y construyen sentido teatral: escenografía, vestuario, iluminación, diseño sonoro.The following is a text that, placing itself in the spot of a regular spectator, critically examines the problematical issues immersed in the play La Cruzada de los Niños. The text will construct the analysis using mainly the dimensions of the spectacle that build up a theatrical sense rather than focusing only on the play's text. It will consider elements such as the scenography, costume design, lighting, and theatrical acoustics.

  18. Central-engine-powered Bright X-Ray Flares in Short Gamma-Ray Bursts: A Hint of a Black Hole–Neutron Star Merger?

    Science.gov (United States)

    Mu, Hui-Jun; Gu, Wei-Min; Mao, Jirong; Hou, Shu-Jin; Lin, Da-Bin; Liu, Tong

    2018-05-01

    Short gamma-ray bursts may originate from the merger of a double neutron star (NS) or the merger of a black hole (BH) and an NS. We propose that the bright X-ray flare related to the central engine reactivity may indicate a BH–NS merger, since such a merger can provide more fallback materials and therefore a more massive accretion disk than the NS–NS merger. Based on the 49 observed short bursts with the Swift/X-ray Telescope follow-up observations, we find that three bursts have bright X-ray flares, among which three flares from two bursts are probably related to the central engine reactivity. We argue that these two bursts may originate from the BH–NS merger rather than the NS–NS merger. Our suggested link between the central-engine-powered bright X-ray flare and the BH–NS merger event can be checked by future gravitational wave detections from advanced LIGO and Virgo.

  19. Distribution patterns of the cold adapted bumblebee Bombus alpinus in the Alps and hints of an uphill shift (Insecta: Hymenoptera: Apidae)

    Czech Academy of Sciences Publication Activity Database

    Biella, Paolo; Bogliani, G.; Cornalba, M.; Manino, A.; Neumayer, J.; Porporato, M.; Rasmont, P.; Milanesi, P.

    2017-01-01

    Roč. 21, č. 2 (2017), s. 357-366 ISSN 1366-638X R&D Projects: GA ČR(CZ) GP14-10035P Grant - others:GA JU(CZ) 152/2016/P Institutional support: RVO:60077344 Keywords : climate change * specialist * rare species Subject RIV: EH - Ecology, Behaviour OBOR OECD: Ecology Impact factor: 1.462, year: 2016 https://link.springer.com/article/10.1007/s10841-017-9983-1

  20. Binding Characteristics of Sphingosine-1-Phosphate to ApoM hints to Assisted Release Mechanism via the ApoM Calyx-Opening

    Science.gov (United States)

    Zhang, Hansi; Pluhackova, Kristyna; Jiang, Zhenyan; Böckmann, Rainer A.

    2016-08-01

    Sphingosine-1-phosphate (S1P) is a lysophospholipid mediator carried by the HDL-associated apoM protein in blood, regulating many physiological processes by activating the G protein-coupled S1P receptor in mammals. Despite the solved crystal structure of the apoM-S1P complex, the mechanism of S1P release from apoM as a part of the S1P pathway is unknown. Here, the dynamics of the wild type apoM-S1P complex as well as of mutants were investigated by means of atomistic molecular dynamics simulations. The potential of mean force for S1P unbinding from apoM reflected a large binding strength of more than 60 kJ/mol. This high unbinding free energy for S1P underlines the observed specificity of the physiological effects of S1P as it suggests that the spontaneous release of S1P from apoM is unlikely. Instead, S1P release and thus the control of this bioactive lipid probably requires the tight interaction with other molecules, e.g. with the S1P receptor. Mutations of specific S1P anchoring residues of apoM decreased the energetic barrier by up to 20 kJ/mol. Moreover, the ligand-free apoM protein is shown to adopt a more open upper hydrophilic binding pocket and to result in complete closure of the lower hydrophobic cavity, suggesting a mechanism for adjusting the gate for ligand access.

  1. The first toxicological study of the antiozonant and research tool ethylene diurea (EDU) using a Lemna minor L. bioassay: Hints to its mode of action.

    Science.gov (United States)

    Agathokleous, Eugenios; Mouzaki-Paxinou, Akrivi-Chara; Saitanis, Costas J; Paoletti, Elena; Manning, William J

    2016-06-01

    The antiozonant and research tool ethylene diurea (EDU) is widely studied as a phytoprotectant against the widespread pollutant ground-surface ozone. Although it has been extensively used, its potential toxicity in the absence of ozone is unknown and its mode of action is unclear. The purpose of this research was to toxicologically assess EDU and to further investigate its mode of action using Lemna minor L. as a model organism. Application of EDU concentrations greater than 593 mg L(-1) (practically 600 mg L(-1)) resulted in adverse inhibition of colony growth. As no-observed-toxic-effects concentration (NOEL) we recommend a concentration of 296 mg L(-1) (practically 300 mg L(-1)). A hormetic response was detected, i.e. stimulatory effects of low EDU concentrations, which may indicate overcompensation in response to disruption in homeostasis. Growth inhibition and suppressed biomass were associated with impacted chlorophyll a fluorescence (ΦPSII, qP and ETR). Furthermore, EDU increased mesophyll thickness, as indicated by frond succulence index. Applications of concentrations ≥593 mg L(-1) to uncontrolled environments should be avoided due to potential toxicity to sensitive organisms and the environment. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. The first toxicological study of the antiozonant and research tool ethylene diurea (EDU) using a Lemna minor L. bioassay: Hints to its mode of action

    International Nuclear Information System (INIS)

    Agathokleous, Eugenios; Mouzaki-Paxinou, Akrivi-Chara; Saitanis, Costas J.; Paoletti, Elena; Manning, William J.

    2016-01-01

    The antiozonant and research tool ethylene diurea (EDU) is widely studied as a phytoprotectant against the widespread pollutant ground-surface ozone. Although it has been extensively used, its potential toxicity in the absence of ozone is unknown and its mode of action is unclear. The purpose of this research was to toxicologically assess EDU and to further investigate its mode of action using Lemna minor L. as a model organism. Application of EDU concentrations greater than 593 mg L −1 (practically 600 mg L −1 ) resulted in adverse inhibition of colony growth. As no-observed-toxic-effects concentration (NOEL) we recommend a concentration of 296 mg L −1 (practically 300 mg L −1 ). A hormetic response was detected, i.e. stimulatory effects of low EDU concentrations, which may indicate overcompensation in response to disruption in homeostasis. Growth inhibition and suppressed biomass were associated with impacted chlorophyll a fluorescence (Φ PSII , q P and ETR). Furthermore, EDU increased mesophyll thickness, as indicated by frond succulence index. Applications of concentrations ≥593 mg L −1 to uncontrolled environments should be avoided due to potential toxicity to sensitive organisms and the environment. - Highlights: • The EDU concentration of 300 mg L −1 should be considered as NOEL. • EDU concentrations ≥600 mg L −1 should not be applied to uncontrolled environments. • Hormetic responses indicate overcompensation in response to homeostasis disruption. - Ethylene diurea is not toxic to sensitive organisms when applied at low concentrations (practically < 600 mg L −1 ).

  3. Clustering of malaria treatment failure (TF) in Daraweesh: hints for host genetic susceptibility to TF with emphasis on immune-modulating SNPs

    DEFF Research Database (Denmark)

    Giha, Hayder A; ElGhazali, Gehad; Nasr, Amre

    2010-01-01

    In malaria, drug resistance and treatment failure (TF) are not synonymous, although are escalating together. Over 9 years of surveillances for malaria morbidity and TF in Daraweesh village in eastern Sudan (1991-2004), 136 donors (15-78 years) from 43 households, treated for 278 malaria episodes ...

  4. A guide to practical radiation protection in medicine. X-Ray Ordinance. Radiation Protection Ordinance. Practice-oriented hints, comments, text compilation

    International Nuclear Information System (INIS)

    Fiebich, M.; Nischelsky, J.E.; Pfeiff, H.; Westermann, K.

    2003-01-01

    This loose-leaf collection has been compiled for users who have to implement the X-ray Ordinance and the Radiation Protection Ordinance at their place of work. It presents all acts, ordinances, safety guides, regulations and recommendations of relevance in connection with the above two ordinances, as well as practical instructions and the full text of technical codes. Radiation protection officers and other persons in charge of radiation protection will find the references, information and advice needed to solve problems encountered. (orig.) [de

  5. Grid-connected photovoltaic systems. Projecting, construction, sales - hints for expert technicians. 3. new rev. ed.; Netzgekoppelte Photovoltaikanlangen. Planung, Errichtung und Verkauf fuer den Handwerksprofi

    Energy Technology Data Exchange (ETDEWEB)

    Sandner, Thomas

    2013-02-01

    Photovoltaic conversion is one of the most efficient and also one of the fastest-growing sustainable technologies. The book starts by presenting the fundamentals of photovoltaic conversion and solar radiation and then proceeds to describe the components of grid-connected PV systems. Other issues of this book consider: On-site visit and selection of a suitable generator array; The Renewable Energy Law and the development of photovoltaic conversion in Germany; Business topics such as costs and prices, marketing, quality assurance; Internal use of solar power.

  6. Hints of popular voice. Through (and in spite of Giuseppe Gioachino Belli and Agustín García Calvo

    Directory of Open Access Journals (Sweden)

    Gerardo Gimona

    2018-01-01

    Full Text Available ¿Así que es para esto para lo que servía la literatura? ¿Para negar, uno tras otro, artículos de fe y dejarnos sin creencia ni idea alguna? ¿Servía, cuando era buena y cuando en algún caso acertaba, para negarse también a sí misma? ¿Y es que debía ante todo negarse a sí misma para poder decir algo que nos sonara a verdad? Pues algo de esto parece ocurrir en los sonetos que Giuseppe Gioachino Belli escribió, como si en ellos hablara directamente el pueblo y no un literato ni un autor culto, en dialecto romanesco; y es esto, precisamente, lo que intentaremos ir ahora comprobando, atendiendo al libro Giuseppe Gioachino Belli. 47 sonetos romanescos con las versiones de Agustín García Calvo (Editorial Lucina, Zamora, 2006.

  7. Cavity mutants of Savinase. Crystal structures and differential scanning calorimetry experiments give hints of the function of the buried water molecules in subtilisins.

    Science.gov (United States)

    Pedersen, J T; Olsen, O H; Betzel, C; Eschenburg, S; Branner, S; Hastrup, S

    1994-09-23

    The subtilisin molecule possesses several internal water molecules, which may be characterised as an integral part of the protein structure. We have introduced specific mutations (T71I, T71S, T71V, T71A and T71G) at position 71 in the subtilisin variant Savinase from Bacillus lentus. This position is involved in a hydrogen bonded network with several internal water molecules, forming a water channel. The water channel and most of the other internal water molecules are positioned in the interface between two half-domains of the subtilisin molecule. The data presented here indicate that the internal water molecules are structural, and may be the result of trapping during the folding process.

  8. Hints of the Early Jehol Biota: Important Dinosaur Footprint Assemblages from the Jurassic-Cretaceous Boundary Tuchengzi Formation in Beijing, China

    Science.gov (United States)

    Xing, Lida; Zhang, Jianping; Lockley, Martin G.; McCrea, Richard T.; Klein, Hendrik; Alcalá, Luis; Buckley, Lisa G.; Burns, Michael E.; Kümmell, Susanna B.; He, Qing

    2015-01-01

    New reports of dinosaur tracksites in the Tuchengzi Formation in the newly established Yanqing Global Geopark, Beijing, China, support previous inferences that the track assemblages from this formation are saurischian-dominated. More specifically, the assemblages appear theropod-dominated, with the majority of well-preserved tracks conforming to the Grallator type (sensus lato), thus representing relatively small trackmakers. Such ichnofaunas supplement the skeletal record from this unit that lacks theropods thus far, proving a larger diversity of dinosaur faunas in that region. Sauropods are represented by medium to large sized and narrow and wide-gauge groups, respectively. The latter correspond with earlier discoveries of titanosauriform skeletons in the same unit. Previous records of ornithischian tracks cannot be positively confirmed. Purported occurrences are re-evaluated here, the trackways and imprints, except of a single possible specimen, re-assigned to theropods. Palecologically the Tuchengzi ichnofauna is characteristic of semi-arid fluvio-lacustrine inland basins with Upper Jurassic-Lower Cretaceous deposits in northern China that all show assemblages with abundant theropod and sauropod tracks and minor components of ornithopod, pterosaur and bird tracks. PMID:25901363

  9. Palga tõusuks jääb raha puudu / Airi Amtmann

    Index Scriptorium Estoniae

    Amtmann, Airi

    2008-01-01

    Paljud Raplamaa omavalitsused on probleemi ees, kuidas kindlustada pedagoogidele 22%-list palgatõusu. Arvamust avaldavad Vigala vallavanem Priit Kärsna, Käru vallavanem Elari Hiis, Rapla abivallavanem Imbi Kalberg, Kohila vallavanem Hillar Kalmet, Juuru vallavalitsuse haridus- ja kultuurispetsialist Aili Normak ja haridusministeeriumi nõunik Riho Raave

  10. Eesti graafika etteaste Londonis / Urmas Viik

    Index Scriptorium Estoniae

    Viik, Urmas, 1961-

    2006-01-01

    Balti graafikanäitusest "Power and man" Londonis Novas galeriis. Eestit esindavad oma loominguga Peeter Allik, Urmas Viik, Kadri Alesmaa, Jaak Visnap, Inga Heamägi, Aili Vahtrapuu. Inglise skulptori Marc Quinni skulptuur rasedast Alison Lapperist Trafalgari väljakul

  11. Metallitüdrukute teistmoodi elu / Kerstin Mahlapuu

    Index Scriptorium Estoniae

    Mahlapuu, Kerstin

    2005-01-01

    Kooliõpilased Aili (15) Saksa Gümnaasiumist, Aija (17) Lasnamäe üldgümnaasiumist, Shardee (16) Pirita majandusgümnaasiumist ja Marionette (17) räägivad oma metal-stiilist ja kuulatavast metal-muusikast

  12. LEADER Eestis - mis toimub, mis toimumas? / Ave Bremse

    Index Scriptorium Estoniae

    Bremse, Ave

    2008-01-01

    LEADER-programmi rakendumise edukusest Eestis. Vt. samas: 1. Kuidas teie kohalikul tegevusgrupil läheb? 2. Mida uut on toonud LEADER teie piirkonda? Küsimustele vastavad: Aili Ilves, Hardi Murula, Merle Adams, Sille Tars, Jaak Vitsur, Mercedes Merimaa ja Piia Kärssin. Lisa: Statistikat ja infot kohalike tegevusgruppide kohta

  13. Skulptorid uurivad vormi tempot

    Index Scriptorium Estoniae

    2002-01-01

    9. XI-8. XII Tallinna Kunstihoones Eesti Kujurite Ühenduse näitus "Tempo di scultura/sculpture agogique/skulptuuri tempo". Kuraatorid Toomas Mikk, Mari-Liis Tammi, Aili Vahtrapuu, kujundaja Mari Kurismaa, avamisel Kaarel Kurismaa performance. Kasutatud Gaston Bachelard'i teose "Kaemus hetkest" tekste

  14. Tartu noored kunstnikud salapärasuse vaimustuses / Margus Kiis

    Index Scriptorium Estoniae

    Kiis, Margus

    2003-01-01

    Tartu Noorte Kunstnike Näitusest Tartu Kunstnike Majas. Iseloomustatud Priit Pajose, Lauri Pajose, Margus Pumpa, Andres Sütevaka, Kaie Luige, Maris Palgi, Külli Suitso, Kadri Kängsepa, Peeter Krossmani, Saimi Kalevi Makkoneni, Kaarel Vulla, Katri Kuuski, Väike Tomi, Meiu Mündi, Karol Kagovere, Meta Narusbeli, Aili Penti, Kene Triive ja Raivo Irdi töid

  15. Gurmee, kiirtoit ja koduköök läbisegi / Heie Treier

    Index Scriptorium Estoniae

    Treier, Heie, 1963-

    2006-01-01

    Rahvusvahelisest joonistuste näitusest "Improvisatsioon" Tallinna Kunstihoones. Oma töid eksponeerivad Tõnis Vint, Evald Okas, Lembit Sarapuu, Aili Vahtrapuu, Albert Gulk, Ülle Marks, Anu Kalm, Vive Tolli, Inga Heamägi, Evi Tihemets, Mare Vint, Maria-Kristiina Ulas, Kuzja Zverev, Tiina Tammetalu jt

  16. Joonistamine Narvas

    Index Scriptorium Estoniae

    2003-01-01

    EKA korraldatud aktsioon "Joonistus kui identiteet" 14. ja 15. VIII Narvas. Kuraator Elnara Taidre, korraldaja Aili Vahtrapuu. 15. VIII avati Narva muuseumi kunstigaleriis joonistuste näitus "Nulla Dies Sine Linea", toimus seminar. Narva-Jõesuus landart-likus liivajoonistusprojektis osalesid Narva kunstnikud ja EKA üliõpilased

  17. 2018-02-20T19:29:11Z https://www.ajol.info/index.php/all/oai oai:ojs ...

    African Journals Online (AJOL)

    The foliar urea based fertilizer Azolon fluid at 75mg a.i/Li applied at full bloom, resulted in 61% fruit set before and 17% after June drop in 2002, slight leaf yellowing, killing and epinasty 7 days after treatment application which disappeared 14 days later but probably started earlier and a slight reduction in leaf photosynthesis ...

  18. Tänane Tartu - naerud, nutud ja hernetondid = Tartu today - laughter, tears and scarecrows / Berk Vaher

    Index Scriptorium Estoniae

    Vaher, Berk, 1975-

    2006-01-01

    Tartu linnaruumist, selle teisenemistest. Eduard Tubina mälestusmärgist (skulptor Aili Vahtrapuu, arhitekt Veronika Valk, heli: Louis Dandrel), Tartu Kaubamajast (arhitekt Raivo Puusepp), Rüütli tänava kujundusest (Rene Valner, Ott Kadarik), Ülikooli tänavast. 5 värv. ill

  19. Eesti kunstnikud, Pariis ja vabadus / Triin Loks

    Index Scriptorium Estoniae

    Loks, Triin

    2011-01-01

    Kaasaegse kunsti näitus "Libérté/Vabadus 2011" Pariisis Château d'Asniéres'is 19. novembrist 4. detsembrini 2011, kuraator Kaia Kiik. Osalevad Kirke Kangro, Aili Vahtrapuu, Viivian Jõemets, Marko Mäetamm, Kiwa, Terje Toomistu, Einike Leppik, Jass Kaselaan, Flo Kasearu, Jaanika Peerna jt.

  20. Sõrve laulupüha peeti tugeva tuule kiuste väljas / Veljo Kuivjõgi

    Index Scriptorium Estoniae

    Kuivjõgi, Veljo, 1951-

    2009-01-01

    Salmel peetud Sõrvemaa 146. aastapäeva laulupühal esinesid Salme külakoor ja Kärla külakoor (juhendaja Anita Kangur), Taritu segakoor (juhendaja Reet Laht), meesansambel Punased Sõstrad ja tantsurühm Lender Taritust (juhendaja Aili Salong)

  1. Library science talks : eleventh season 2005

    CERN Multimedia

    2005-01-01

    The Swiss National Library in Berne, the Association of International Librarians and Information Specialists AILIS and the CERN Scientific Information Service are pleased to announce their 2005 series of Library Science Talks. The series offers library and archive staff the possibility of learning from and communicating with personalities in library services and organizations. The talks cover important and topical issues for librarians.

  2. Ühiskondlik süüdistus : EV Ülemkohtu esimehe, nõukogude teenelise juristi J. Kirikali, Ülemkohtu liikmete U. Penderi ja A. Viljardi ning EV prokuröri L. Urge vastu / Enn Sarv

    Index Scriptorium Estoniae

    Sarv, Enn, 1921-2008

    1992-01-01

    1991. a. 27. veebruari Ülemkohtu pleenumi määrusest, mis puudutas 1946. a. süüdi mõistetud koolinoori (Ageeda-Andrea Paavel, Aili Jürgenson, Eino Valdmaa, Lia Frei, Juhan Kuusk). Lisatud määruse täistekst

  3. The Coast Artillery Journal. Volume 72, Number 2, February 1930

    Science.gov (United States)

    1930-02-01

    hmlisfar further study alang this line, we shall also.co.nfine ourselvesto the "cantact" effect of this agent, as distinguished fram what we may call its...study alang the lines we are nGW cansidering. Mustard is an aily liquid af abo.utthe cam-listencyaf heavy lubricating oil. Dispersed either by artillery

  4. Tartu Ülikool 375 / interv. Rein Raudvere

    Index Scriptorium Estoniae

    2007-01-01

    Küsitlus: Mida on teile andnud Tartu Ülikool? Millest oleksite jäänud ilma, kui poleks olnud õnne õppida Tartu Ülikoolis? Vastavad: Tõnis Lukas, Hannes Kaljujärv, Aili Paju, Ain Kallis, Aarne Liiv ja Hans Trass. Vt. samas: EV ministrid TÜ vilistlased; Riigikogu liikmed TÜ vilistlased

  5. ASESMEN INSTALATUR LISTRIK BERBASIS KEBUTUHAN INDUSTRI JASA KONSTRUKSI KETENAGALISTRIKAN

    Directory of Open Access Journals (Sweden)

    Sukardi Sukardi

    2015-10-01

    AN ASSESSMENT OF ELECTRICITY CONSTRUCTION BASED ON THE NEED OF SERVICE INDUSTRY OF ELECTRICAL INSTALLER Abstract The aim of this research was to produces an assessment of electricity construction service industrial needs-based electrical installer (AILIS. The research was developed through three stages, namely: the design, the limited trial, and expanded trials. The design consists of: pre-survey, studies on the research findings, problem analysis and analysis of electric installer performance. The limited trial included: validation of the AILIS through expert judgment and the user, analysis and revision. The expanded trial included: data collecting, analysis, revision, and dissemination. The research instruments consisting of a questionnaire and observation sheets were distributed to capture the data needed for the analysis. The subjects for the implementation were 210 respondents as the managers of electricity construction service industrial companies in West Sumatra Province. The CFA was used to verify that the developed model fit the AILIS. The finding shows that AILIS is excellent at assessing electrical installer performance in the electricity construction service industry, with indicator the design of electrical installation, the construction of electrical installation, the commissioning of electrical installation, the operation, and the maintenance of electrical installation. Keywords: assessment, confirmatory factor analysis, electrical installer

  6. Linnaruum - kas ainult arhitektuur? / Mari-Liis Tammi-Kelder

    Index Scriptorium Estoniae

    Tammi-Kelder, Mari-Liis

    2004-01-01

    25. IV Tallinna Õpetajate Majas Eesti Kujurite Ühenduse seminar, mis keskendub monumentaalskulptuurile kaasaegses linnaruumis. Esinevad Bernard Gerboud Pariisist, Pekka Jylhä Soomest, Kristaps Gulbis ja Irena Buzinska Lätist, Jüri Soolep, Triin Ojari, Rael Artel, Jaan Elken ja Aili Vahtrapuu. Seminari juhatab Jaak Soans

  7. Galeriid / Reet Varblane

    Index Scriptorium Estoniae

    Varblane, Reet, 1952-

    1999-01-01

    Allen Jonesi litograafiate näitus galeriis "Vaal". Paul Rodgersi projektist Tartus Vanas anatoomikumis. Aili Vahtrapuu "Vee ruum" ja Jaak Soansi "Projektsioonid" Kunstihoone galeriis. Skulptorite ühenduse ideenäitus "Akvaarium" Rotermanni soolalao keldrisaalis. Idee autor Terje Ojaver.

  8. Kui tegelikkusest on kõrini / Tiina Väljaste

    Index Scriptorium Estoniae

    Väljaste, Tiina, 1964-

    2008-01-01

    Eesti, läti ja leedu nüüdiskunsti näitus Pariisi kunstikeskuses Cité Internationale des Arts. Eesti väljapaneku kuraator on Aili Vahtrapuu. Pikemalt Jüri Ojaveri installatsioonist "Kirves ja kuu", Urmas Viigi graafilis-tekstilisest karusaagast. Nimetatud teisi osalejaid

  9. Eesti kunst Pariisis

    Index Scriptorium Estoniae

    2008-01-01

    Eesti, läti ja leedu kaasaegse kunsti näitus Pariisis Cite Internationale des Arts galeriis. Eesti osa kuraator on Aili Vahtrapuu. Eksponeeritakse Ene-Liis Semperi, Anu Põdra, Peeter Alliku, Anu Kalmu, Virge Jõekalda jt. kunstnike loomingut

  10. Aasta rosina sai "Kui Arno isaga koolimajja jõudis..."

    Index Scriptorium Estoniae

    2008-01-01

    Eesti Lastekirjanduse Keskus andis 2007. a. Rosina auhinna Oskar Lutsu "Kevade" kommenteeritud kooliväljaandele: "Kui Arno isaga koolimajja jõudis... " / [Oskar Lutsu "Kevade" 14. trüki põhjal koostanud Aili Kalavus, Mare Müürsepp]. Tallinn : Ilo, 2007

  11. Kujurid ei olegi nikerdajad / Aarne Mäe

    Index Scriptorium Estoniae

    Mäe, Aarne, 1967-

    1998-01-01

    Sümpoosioni 'Puu '98' (korraldaja Heiki Kongi) raames Sagadis toimunud puuskulptuuride valmistamisest, kus osalesid Aime Kuulbusch, Aili Vahtrapuu, Hille ja Lembit Palm, Urmas Rauba, Tiiu Kirsipuu, Steve Lester, ning mille tulemusi eksponeeritakse koos Valga- ja Pärnumaal valminutega Rocca al Mares

  12. Vabaduse ilmingud / Nicolas Boldych ; tõlkinud Viiviann Jõemets

    Index Scriptorium Estoniae

    Boldych, Nicolas

    2011-01-01

    Eesti kultuurifestivali raames eesti kaasaegse kunsti näitus "Vabadus" ("Liberté") Pariisis Château d'Asniéres's 19.11.-04.12.2011, kuraator Kaia Kiik. Loetletud kunstnikud. Kirke Kangro, Aili Vahtrapuu, Louis Dandreli ja Viiviann Jõemetsa, Terje Ojaveri, Jüri Ojaveri, Marko Mäetamme, Ly Lestbergi, Einike Leppiku, Jaanika Peerna, Kaia Kiige, Flo Kasearu, Jass Kaselaane ja Veronika Valgu töödest

  13. Milleks monumenti = Why a monument? / Heie Treier

    Index Scriptorium Estoniae

    Treier, Heie, 1963-

    2006-01-01

    2006. a. toimunud Jüri Lotmani mälestusmärgi konkursist, Mati Karmini ja Andres Lunge võidutööst. Monumentide positiivseid näiteid: Tubina plats Tartus (Aili Vahtrapuu, Veronika Valk, Louis Dandrel), ideekavandid: Estonia teatri juubelimonument Tallinnas (Tiiu Kirsipuu, Üla Koppel) ja Eesti iseseisvuse monument Pärnus Rüütli platsil (Mart Aas, Kaarel Eelma, Mikk Mutso). Bibl. lk. 73

  14. Arhitektuur rahu toomas / Triin Ojari

    Index Scriptorium Estoniae

    Ojari, Triin, 1974-

    2008-01-01

    Näitus "Identiteet ja arhitektuur [post-]konfliktsetes piirkondades" ("Peacebuilding") 30. okt.-9. nov. 2008 Casa dell' Architetturas Roomas. Üldkuraator Pippo Ciorra. Näitus keskendus Euroopa idaosa, Balkanimaade ja Lähis-Ida regioonile. Eestist oli näitusele valitud 7 objekti, autoriteks bürood Kolm Pluss Üks, KOKO Arhitektid, Kavakava, arhitektid Pekka Vapaavuori, Siiri Vallner, Indrek Peil, Tomomi Hayashi, Veronika Valk ja Aili Vahtrapuu

  15. Reaalsust taltsutades / Jean-Louis Poitevin ; tõlk. Mailis Seero

    Index Scriptorium Estoniae

    Poitevin, Jean-Louis

    2008-01-01

    Läti, leedu ja eesti kunstnike ühisnäitus Pariisi Cite Internationale des Arts'is kuni 26. X. Kuraatorid: Aili Vahtrapuu, Liena Bondare, Birute Pankunaite. Miks Mitrevicsi, Inta Brunina, Laura Garbshtiene, Reiu Tüüri, Anu Kalmu, Peeter Alliku, Urmas Viigi, Anu Põdra, Jüri Ojaveri, Jaanus Samma, Ene-Liis Semperi, Mari-Liis Tammi, Angelika Schneideri ja Virge Jõekalda töödest

  16. "Habitarel" valitses kerge minimalism

    Index Scriptorium Estoniae

    2003-01-01

    17. mööbli- ja sisustusmess "Habitare" Helsingi Messikeskuses. Noorte sisekujundajate projektikonkursil "TILA+" parim Soome Kunstikõrgkooli õpilaste Marika Aro ja Nana Turuneni töö "Tulemüür". Eesti tootjate esindatus (TVMK kasevineerist tooli ja lauad, Toom Tekstiili villatekid ja padjad). Muljeid disainiüliõpilaselt Anni Kalmuselt, sisearhitekt Aili Aasojalt, TVMK reklaamijuhilt Viivi Rooselt. 4 ill

  17. Building Partnership Capacity at the Ministerial Level to Improve Gender Equality

    Science.gov (United States)

    2014-06-13

    suggested I read some of the research of Dr. Aili Tripp and Peace Medie which were of considerable help to my literature review. Most importantly, I am...59 The Consequences of Culture–Policy vs . Implementation ....................................... 62 Section Three: The Whole of Government...2013, 387). The 2008 documentary , Pray the Devil Back to Hell tells the story of a group of Liberian women who would not succumb to fear. The film

  18. Upanişadların Temel Kavramları, Getirdiği Yeni Yaklaşımlar ve Hint Dinî ve Felsefî Dünyasına Katkıları

    Directory of Open Access Journals (Sweden)

    Ali İsra Güngör

    2015-11-01

    Full Text Available Hindu holy literature is composed of several texts. Vedic literature is divided by tradition into two categories: Shruti that is heard (revelation and Smriti that is remembered (not revelation. The Upanishads are part of the Shruti. They have special place and importance in this rich literature. Because, Upanishads are remarkable with respect to the content and contains new religious and philosophic thoughts. In this respect, theological bases of the concepts such as karmareincarnation and Moksha which are the keystones of Hinduism take place firstly in Upanishad texts. On the other hand, some thoughts presented by Upanishads have deeply affected Hindu culture and philosophy. Thus effects of Upanishad texts on Hindu religious beliefs, culture and philosophy are still prevailing today

  19. Ma armtub säda ŷdugt, kus mytk līb pūtumi : ehk Ma armastan seda õhtut, kus mõttest saab puudutus / Mati Hint

    Index Scriptorium Estoniae

    Hint, Mati, 1937-

    2014-01-01

    Arvustus: Ķempi Kārl. Toini sina = Teine sina / tõlge eesti keelde ja järelsõna: Karl Pajusalu. Tallinn : Eesti Keele Sihtasutus, 2013 ; Ķempi Kārl. Salats joug kolm aģa = Salatsi jõe kolm kallast = Salacas upes trīs krasti / tõlge eesti keelde: Karl Pajusalu, tõlge läti keelde: Valts Ernštreits. Tartu : Liivi Sõprade Selts, 2013

  20. Kaks kaptenit / Krister Kivi

    Index Scriptorium Estoniae

    Kivi, Krister, 1975-

    2007-01-01

    Väliseestlased Mart ja Peter Hint on teinud silmapaistvat karjääri Ameerika Lennunduses. Mart Hint töötab Boening 767 kaptenina lennukompaniis Delta, Peter Hint töötab lennukompaniis American Airlines

  1. Methodology for the Model-based Small Area Estimates of Cancer-Related Knowledge - Small Area Estimates

    Science.gov (United States)

    The HINTS is designed to produce reliable estimates at the national and regional levels. GIS maps using HINTS data have been used to provide a visual representation of possible geographic relationships in HINTS cancer-related variables.

  2. Disain on kõikjal / Kristjan Mändmaa, Kristjan Sisa

    Index Scriptorium Estoniae

    Mändmaa, Kristjan, 1973-

    2007-01-01

    Disainiaasta raames Eestis rändavast näitusest "Disain tuleb külla" ja saatenäitusest. Meie linnaruumis leiduvatest esemetest: ukse käepide "Classic K4", jalgrattahoidja, tuvikujuline tänavatõkis (Simson Seakülast), kanalisatsiooniluuk, prügikast (Aili Vahtrapuu), betoonjalgadega pink (Jaan Koik), kultuurimälestise silt, arhitektuurimälestise silt (Jaanus Miitel), postkast, ostukäru, piktogrammid, 7-SEG numbrid, EXIT-märk, liuguksed, piktogramm 1974 (Roger Cook, Don Shanosky), porivaip, Lithos font (Carol Twombly)

  3. Rõõmus kunst / Andri Ksenofontov

    Index Scriptorium Estoniae

    Ksenofontov, Andri, 1962-

    2010-01-01

    Alessandro Damiano (Itaalia) ratsamonumenditeemaline näitus "Varju-uurimus" ("Studi d'ombra") Tallinna Linnagaleriis 30. maini 2010. Tim Daviese (Wales) näitus "Seeria" 30. 04.-16. 05. 2010 ja Piero Steinle (Itaalia) näitus "Sinu päevad on loendatud" 13. juunini 2010 Tallinna Kunstihoone galeriis. Aili Vahtrapuu näitus "Naeruvõlu" Hobusepea galeriis 12.-24. maini 2010. Maria-Kristiina Ulase joonistuste näitus "Kunstniku nahk noore koera seljas" Haus Galeriis 18. juunini 2010

  4. Lõigutud aeg / Vappu Thurlow

    Index Scriptorium Estoniae

    Thurlow, Vappu, 1960-

    2007-01-01

    Adamson-Ericu muuseumis kuni 25. XI avatud näitusest "Lõigutud aeg". Henri Bergsoni ajakäsitlusest. Töödest: Anu Juuraku "Suplejad", Ilkka Väätti "Kinaalda" ja "Ton", Aili Vahtrapuu "Vaagen vabale vaimule", Marje Üksise "Nii ma lähen", Annemie Bogaerts'i "Lõpp on vaikus", Siim-Tanel Annuse "24 tundi", Lynne Allen'i "Saak", Eve Kiileri "Ilu etalonide arhiivid", Ingrid Ledent'i "Mälu kestev olemine, mis muudab mineviku olevikuks", Raoul Kurvitza "Aeg ja lugu"

  5. Structure sismique du socle paléozoïque du bassin des Doukkala, Môle côtier, Maroc occidental. Indication en faveur de l'existence d'une phase éo-varisqueSeismic structure of the Doukkala basin, Palaeozoic basement, western Morocco: a hint for an Eovariscan fold-and-thrust belt

    Science.gov (United States)

    Echarfaoui, Hassan; Hafid, Mohamed; Salem, Abdallah Aı̈t

    2002-01-01

    Seismic profiles and well data from the Doukkala basin unravel the structure of the Palaeozoic basement and suggest that this coastal zone of western Morocco was affected by a compressive phase during the Frasnian. This resulted in the formation of upright, plurikilometric folds associated with reverse faults (North Doukkala), and of asymmetrical folds associated with mostly west verging ramps (South Doukkala). Folding involved all pre-Upper Frasnian formations and caused partial or total hiatus of Upper Frasnian-Strunian strata. This event can be correlated with the orogenic phase reported from more internal domains of the Morocco Hercynian belt, where it is referred to as the 'Bretonne' or 'Eovariscan' phase. To cite this article: H. Echarfaoui et al., C. R. Geoscience 334 (2002) 13-20

  6. Claves para la comprensión de las relaciones entre la lengua, la cultura y la sociedad yuhup: una perspectiva etnolingÜística* Hints towards the comprehension of the relationship between the yuhup language, culture and society: an ethnolinguistic perspective

    Directory of Open Access Journals (Sweden)

    Ana María Ospina Bozzi

    2008-12-01

    Full Text Available Este artículo ofrece una mirada etnolingüística sobre algunos aspectos del pueblo yuhup, mediante un análisis que relaciona la lengua, la sociedad y la cultura. A manera de contextualización se presenta un resumen de la indagación realizada, se describe el entorno cultural y lingüístico de los pueblos nómades del noroeste amazónico y se evalúa el estado de la investigación sobre ellos. Se abordan aspectos sociales y culturales del pueblo yuhup, ilustrando -con datos lingüísticos- su historia reciente, su ocupación del territorio, y su categorización de plantas, animales y nociones espaciales.This paper presents an ethnolinguistic overview of the yuhup community by analyzing the way language, society, and culture are related. A contextualization of this relationship is outlined by means of a summary of the research carried out, a description of the cultural and linguistic environment of nomad communities in the Northeast Amazon, and an evaluation of research on these communities. Social and cultural aspects of the yuhup community are dealt with taking into account linguistic data, their recent history, their occupied territory, and their categorization of plants, animals, and spatial notions.

  7. Collaboration and peer tutoring in chemistry laboratory education

    NARCIS (Netherlands)

    Ding, N.; Harskamp, E.G.

    2011-01-01

    The aim of this study is to examine the effectiveness of collaborative learning with hints and peer tutoring with hints, and individual learning with hints in chemistry laboratory education in a secondary school. A total of 96 eleventh graders participated in this study. The study has a randomized

  8. evaluation of total annual costs of heat exchanger networks using

    African Journals Online (AJOL)

    This study presents pinch analysis of some heat exchanger networks (HENs) problems using Hint integration (HINT) software. Three examples reported to have been solved using different approaches by various researchers to obtain the least possible total annual cost (TAC) were solved using the Hint software. In this work ...

  9. NNS computing facility manual P-17 Neutron and Nuclear Science

    International Nuclear Information System (INIS)

    Hoeberling, M.; Nelson, R.O.

    1993-11-01

    This document describes basic policies and provides information and examples on using the computing resources provided by P-17, the Neutron and Nuclear Science (NNS) group. Information on user accounts, getting help, network access, electronic mail, disk drives, tape drives, printers, batch processing software, XSYS hints, PC networking hints, and Mac networking hints is given

  10. Tammsaare kirjanduspreemiate laureaadid / šaržid: Hugo Hiibus

    Index Scriptorium Estoniae

    1996-01-01

    Preemiat on antud välja alates 1978. a. Preemia saajad : Helene Siimisker. 'A. H. Tammsaare pildikroonika eluteest ja tööst'. (1977); Juhan Peegel. 'Ma langesin esimesel sõjasuvel'. (1978); Ilmar Sikemäe. 'Kirjad Vargamäelt'. (1979); Vello Lattik. 'Kuus head inimest'. (1980); Veera Saar. 'Aprillipäev'. (1981); Mats Traat. 'Karukell, kurvameelsuse rohi'. (1982); Raimond Kaugver. 'Vana mees tahab koju'. (1983); Mari Saat. 'Õun valguses ja varjus'. (1984); Viivi Luik. 'Seitsmes rahukevad'. (1985); Heino Kiik. 'Elupadrik'. (1986); Luise Vaher. 'Põlev pärisosa'. (1987); Hando Runnel. 'Laulud eestiaegsetele meestele'. (1988); Arvo Valton. 'Masendus ja lootus'. (1989); Kalju Lepik. 'Rukkilille murdmise laul'. (1990); Illar Mõttus. Dramatiseering 'Jumalaga Vargamäe'. (1991); Leelo Tungal. 'Barbara ja suvekoerad'. (1992); Aili Viitar. 'Kummelimuru'. (1993); Albert Uustulnd. 'Rajud ei rauge', 'Lummav meri'. (1994)

  11. Vanadust käsitlev projekt Tallinna Kunstihoones

    Index Scriptorium Estoniae

    2005-01-01

    Tallinna Kunstihoones Reet Varblase kureeritud näitus "Homo grandis natu", mis käsitleb vanaduse ja vananemise tähendust ja rolli praeguses ühiskonnas. Osalejaid: Boaz Tal, Eveli Varik, Ly Lestberg, Mare Mikof, Aili Vahtrapuu, Jaan Paavle, Terje Ojaver, Marge Monko, Terje Tunis, Tatjana Antoshina, Valeri Vinogradov, Peeter Laurits, Toomas Kalve, Jüri Ojaver. 15. IV toimuva seminari "Eesti vananemispoliitika täna ja homme" ning 21., 28. IV, 5., 12. V toimuva loengusarja kava. 16. IV peab Boaz Tal loengu arhetüüpidest ja mälust, tutvustab oma töid. 21. IV avatakse Katarzyna Kozyra videoinstallatsioon "Naiste saun". 2. V performance'i-festival "Diverse universe", loetletud osalejaid

  12. News from the Library: Celebrating 20 years of "Library Science Talks"

    CERN Multimedia

    CERN Library

    2014-01-01

    The CERN Library (GS-SIS Group) is promoting activities and initiatives to foster better communication and closer cooperation amongst international librarians and information specialists in the Geneva - Lausanne area.   Great changes that have occurred in the world of information during the last two decades. For this reason, the CERN Library, in cooperation with the Swiss National Library and the Association of International Librarians and Information Specialists (AILIS), sponsors a programme of "Library Science Talks", which consists of six presentations per year given by internationally recognised specialists in the field, providing an opportunity to learn about the trends in our profession. This series of talks was launched in 1995 by Corrado Pettenati, CERN Head Librarian at that time. The idea was that CERN Library staff would benefit from hearing about current projects and products and could then apply some of the ideas to the library. This initiative was&...

  13. INTRODUCCIÓN A LA METODOLOGÍA DE LA INVESTIGACIÓN EN BIOÉTICA: SUGERENCIAS PARA EL DESARROLLO DE UN PROTOCOLO DE INVESTIGACIÓN CUALITATIVA INTERDISCIPLINARIA INTRODUÇÃO À METODOLOGIA DA PESQUISA EM BIOÉTICA: SUGESTÕES PARA O DESENVOLVIMENTO DE UM PROTOCOLO DE PESQUISA QUALITATIVA INTRODUCTION TO INVESTIGATION’S METHODOLOGY IN BIOETHICS: HINTS FOR THE DEVELOPMENT OF AN INTERDISCLINARY QUALITATIVE PROTOCOL

    Directory of Open Access Journals (Sweden)

    María de la Luz Casas Martínez

    2008-01-01

    Full Text Available El avance de la bioética requiere de la ciencia para su desarrollo. La investigación en bioética parte de la interdisciplinariedad, lo cual complica su realización. Uno de los puntos conflictivos para aquellos que se inician en la investigación es la constitución de un adecuado protocolo. En este trabajo se pretende exponer un panorama general sobre los pasos de la integración de un protocolo con base en la investigación cualitativa.O desenvolvimento da ciência provoca o avanço da bioética. A pesquisa em bioética parte da interdisciplinaridade, a qual complica sua realização. Um dos pontos conflitivos para iniciantes na pesquisa é a constituição de um protocolo adequado. Este trabalho pretende expor um panorama geral sobre os passos da integração de um protocolo com base na pesquisa qualitativa.Bioethics’ advance requires science’s support for its development. Bioethics’ investigation stems from interdisciplinarity which, of course, complicates its fulfilment. One of the items in conflict for beginners in the investigation field is the establishment of a protocol. This work pretends to state a general overview about the steps that have to be taken to integrate a protocol based on qualitative investigation.

  14. Masking Release for Igbo and English

    OpenAIRE

    Ebem, Deborah U.; Desloge, Joseph G.; Reed, Charlotte M.; Braida, Louis D.; Uguru, Joy O.

    2013-01-01

    In this research, we explored the effect of noise interruption rate on speech intelligibility. Specifically, we used the Hearing In Noise Test (HINT) procedure with the original HINT stimuli (English) and Igbo stimuli to assess speech reception ability in interrupted noise. For a given noise level, the HINT test provides an estimate of the signal-to-noise ratio (SNR) required for 50%-correct speech intelligibility. The SNR for 50%-correct intelligibility changes depending upon the interruptio...

  15. Forschungszentrum Juelich, Institut fuer Kernphysik/COSY. Annual report 2007

    Energy Technology Data Exchange (ETDEWEB)

    Buescher, M.; Hanhart, C.; Krewald, S.; Machner, H.; Maier, R.; Meissner, U.G.; Ritman, J.; Stockhorst, H.; Stroeher, H. (eds.)

    2008-03-15

    The following topics are dealt with, Physics at COSY, external experiments, theoretical investigations. COSY operation and developments, preparation for FAIR. See hints under the relevant topics. (HSI)

  16. Electronic Journals: Publishing via Internet's World Wide Web.

    Science.gov (United States)

    van Brakel, Pieter A.

    1995-01-01

    Provides hints for setting up and maintaining a multimedia scholarly journal. Details include limitations of paper and electronic journals, and requirements for publishing successful electronic journals. (JKP)

  17. Forschungszentrum Juelich, Institut fuer Kernphysik/COSY. Annual report 2007

    International Nuclear Information System (INIS)

    Buescher, M.; Hanhart, C.; Krewald, S.; Machner, H.; Maier, R.; Meissner, U.G.; Ritman, J.; Stockhorst, H.; Stroeher, H.

    2008-03-01

    The following topics are dealt with, Physics at COSY, external experiments, theoretical investigations. COSY operation and developments, preparation for FAIR. See hints under the relevant topics. (HSI)

  18. Unsupervised MDP Value Selection for Automating ITS Capabilities

    Science.gov (United States)

    Stamper, John; Barnes, Tiffany

    2009-01-01

    We seek to simplify the creation of intelligent tutors by using student data acquired from standard computer aided instruction (CAI) in conjunction with educational data mining methods to automatically generate adaptive hints. In our previous work, we have automatically generated hints for logic tutoring by constructing a Markov Decision Process…

  19. Web-Based Quiz-Game-Like Formative Assessment: Development and Evaluation

    Science.gov (United States)

    Wang, Tzu-Hua

    2008-01-01

    This research aims to develop a multiple-choice Web-based quiz-game-like formative assessment system, named GAM-WATA. The unique design of "Ask-Hint Strategy" turns the Web-based formative assessment into an online quiz game. "Ask-Hint Strategy" is composed of "Prune Strategy" and "Call-in Strategy".…

  20. Intracellular pH distribution as a cell health indicator in Saccharomyces cerevisiae

    DEFF Research Database (Denmark)

    Aabo, Thomas; Glückstad, Jesper; Siegumfeldt, Henrik

    2011-01-01

    .d.(pHint)) to describe the internal pH distributions. The cellular pH distributional response to external stress such as heat has not previously been determined. In this study, the intracellular pH (pHi) and the s.d.(pHint) of Saccharomyces cerevisiae cells exposed to supralethal temperatures were measured using...

  1. Network Security Risks of Online Social Networking in the Workplace

    Science.gov (United States)

    2013-11-01

    Facebook explains pornographic shock spam, hints at browser vulnera- bility, nakedsecurity. URL – http://nakedsecurity.sophos.com/2011/11/16/ facebook...explains- pornographic -shock-spam-hints-at-browser-vul nerability/. 22 UNCLASSIFIED UNCLASSIFIED DSTO–GD–0772 44. Blatz, J. (2011) CSRF: attack and

  2. Adaptive filtering primer with Matlab

    CERN Document Server

    Poularikas, Alexander D

    2006-01-01

    INTRODUCTIONSignal ProcessingAn ExampleOutline of the TextDISCRETE-TIME SIGNAL PROCESSINGDiscrete Time SignalsTransform-Domain Representation of Discrete-Time SignalsThe Z-TransformDiscrete-Time SystemsProblemsHints-Solutions-SuggestionsRANDOM VARIABLES, SEQUENCES, AND STOCHASTIC PROCESSESRandom Signals and DistributionsAveragesStationary ProcessesSpecial Random Signals and Probability Density FunctionsWiener-Khinchin RelationsFiltering Random ProcessesSpecial Types of Random ProcessesNonparametric Spectra EstimationParametric Methods of power Spectral EstimationProblemsHints-Solutions-SuggestionsWIENER FILTERSThe Mean-Square ErrorThe FIR Wiener FilterThe Wiener SolutionWiener Filtering ExamplesProblemsHints-Solutions-SuggestionsEIGENVALUES OF RX - PROPERTIES OF THE ERROR SURFACEThe Eigenvalues of the Correlation MatrixGeometrical Properties of the Error SurfaceProblemsHints-Solutions-SuggestionsNEWTON AND STEEPEST-DESCENT METHODOne-Dimensional Gradient Search MethodSteepest-Descent AlgorithmProblemsHints-Sol...

  3. Caffeine at a Moderate Dose Did Not Affect the Skeletal System of Rats with Streptozotocin-Induced Diabetes.

    Science.gov (United States)

    Folwarczna, Joanna; Janas, Aleksandra; Cegieła, Urszula; Pytlik, Maria; Śliwiński, Leszek; Matejczyk, Magdalena; Nowacka, Anna; Rudy, Karolina; Krivošíková, Zora; Štefíková, Kornélia; Gajdoš, Martin

    2017-10-30

    Diabetes may lead to the development of osteoporosis. Coffee drinking, apart from its health benefits, is taken into consideration as an osteoporosis risk factor. Data from human and animal studies on coffee and caffeine bone effects are inconsistent. The aim of the study was to investigate effects of caffeine at a moderate dose on the skeletal system of rats in two models of experimental diabetes induced by streptozotocin. Effects of caffeine administered orally (20 mg/kg aily for four weeks) were investigated in three-month-old female Wistar rats, which, two weeks before the start of caffeine administration, received streptozotocin (60 mg/kg, intraperitoneally) alone or streptozotocin after nicotinamide (230 mg/kg, intraperitoneally). Bone turnover markers, mass, mineral density, histomorphometric parameters, and mechanical properties were examined. Streptozotocin induced diabetes, with profound changes in the skeletal system due to increased bone resorption and decreased bone formation. Although streptozotocin administered after nicotinamide induced slight increases in glucose levels at the beginning of the experiment only, slight, but significant unfavorable changes in the skeletal system were demonstrated. Administration of caffeine did not affect the investigated skeletal parameters of rats with streptozotocin-induced disorders. In conclusion, caffeine at a moderate dose did not exert a damaging effect on the skeletal system of diabetic rats.

  4. Caffeine at a Moderate Dose Did Not Affect the Skeletal System of Rats with Streptozotocin-Induced Diabetes

    Directory of Open Access Journals (Sweden)

    Joanna Folwarczna

    2017-10-01

    Full Text Available Diabetes may lead to the development of osteoporosis. Coffee drinking, apart from its health benefits, is taken into consideration as an osteoporosis risk factor. Data from human and animal studies on coffee and caffeine bone effects are inconsistent. The aim of the study was to investigate effects of caffeine at a moderate dose on the skeletal system of rats in two models of experimental diabetes induced by streptozotocin. Effects of caffeine administered orally (20 mg/kg aily for four weeks were investigated in three-month-old female Wistar rats, which, two weeks before the start of caffeine administration, received streptozotocin (60 mg/kg, intraperitoneally alone or streptozotocin after nicotinamide (230 mg/kg, intraperitoneally. Bone turnover markers, mass, mineral density, histomorphometric parameters, and mechanical properties were examined. Streptozotocin induced diabetes, with profound changes in the skeletal system due to increased bone resorption and decreased bone formation. Although streptozotocin administered after nicotinamide induced slight increases in glucose levels at the beginning of the experiment only, slight, but significant unfavorable changes in the skeletal system were demonstrated. Administration of caffeine did not affect the investigated skeletal parameters of rats with streptozotocin-induced disorders. In conclusion, caffeine at a moderate dose did not exert a damaging effect on the skeletal system of diabetic rats.

  5. ECOOL 1984

    International Nuclear Information System (INIS)

    Poth, H.

    1984-07-01

    These proceedings contain the articles presented at the named workshop. They deal with electron cooling and its applications, especially in heavy ion storage rings. See hints under the relevant topics. (HSI)

  6. Spectroscopy and Photometry of CAI-rich asteroids

    Science.gov (United States)

    Tanga, P.; Devogele, M.; Bendjoya, Ph.; Cellino, A.; Surdej, J.

    2017-09-01

    Asteroids with an anomalous amount of primitive elements, formed in ancient times in the solar nebula, exist. Our study confirms their nature and provides hints to the interpretation of the ancient evolution of asteroids.

  7. Calculus of variations mechanics, control and other applications

    CERN Document Server

    MacCluer, Charles R

    2012-01-01

    First truly up-to-date treatment offers a simple introduction to optimal control, linear-quadratic control design, and more. Broad perspective features numerous exercises, hints, outlines, and appendixes, including a practical discussion of MATLAB. 2005 edition.

  8. No Appetite? How to Get Nutrition during Cancer Treatment

    Science.gov (United States)

    ... than to eat something. During illness, treatment or recovery, your need for calories and protein may be ... patient-education/eating-hints. Accessed Jan. 5, 2015. Nutrition in cancer care (PDQ). National Cancer Institute. http:// ...

  9. Shiftwork Scheduling for the 1990s.

    Science.gov (United States)

    Coleman, Richard M.

    1989-01-01

    The author discusses the problems of scheduling shift work, touching on such topics as employee desires, health requirements, and business needs. He presents a method for developing shift schedules that addresses these three areas. Implementation hints are also provided. (CH)

  10. Experiments at CERN in 1981

    International Nuclear Information System (INIS)

    1981-08-01

    This report contains the preliminary abstracts of the current experiments at the CERN SPS synchrotron, the anti p colliding beams, the CERN ISR, the CERN PS synchrotron, and the CERN synchrocyclotron. See hints under the relevant topics. (HSI)

  11. Fulltext PDF

    Indian Academy of Sciences (India)

    Madhu

    humans and animals against excessive pulmonary pressures and prevent the occurrence of .... Natural stimulation of J receptors produces dry cough in addition to .... committees and meetings his eyes would blaze with anger at the first hint of ...

  12. Crystal Ball contributions to the 9th international workshop on photon-photon collisions, La Jolla, 23-26 March 1992

    International Nuclear Information System (INIS)

    Bienlein, J.K.

    1992-06-01

    This report contains two articles concerning new Crystal Ball data on resonance formation by γγ collisions and the representation of such results by helicity amplitudes. See hints under the relevant topics. (HSI)

  13. Res Publica hakkab kaaluma Kohtla-Järve võimuliidust lahkumist / Erik Gamzejev

    Index Scriptorium Estoniae

    Gamzejev, Erik, 1967-

    2002-01-01

    Ilmunud ka: Severnoje Poberezhje 19. nov. lk. 1. Res Publica eestseisuse ettepanek Kohtla-Järve osakonnale lahkuda koalitsioonist. Osakonna juhatuse otsus esitada Hants Hint volikogu esimehe kandidaadiks. Res Publica liikmete käitumise arutelu aukohtus

  14. Tracking Code for Microwave Instability

    International Nuclear Information System (INIS)

    Heifets, S.; SLAC

    2006-01-01

    To study microwave instability the tracking code is developed. For bench marking, results are compared with Oide-Yokoya results [1] for broad-band Q = 1 impedance. Results hint to two possible mechanisms determining the threshold of instability

  15. Gross properties of nuclei and nuclear excitations XXI

    International Nuclear Information System (INIS)

    Feldmeier, H.

    1993-01-01

    These proceedings contain the articles and contributed papers presented at the named workshop. They are concerned with highly excited nuclear matter and relativistic heavy ion reactions together with some related topics. See hints under the relevant topics. (HSI)

  16. Are demand forecasting techniques applicable to libraries?

    OpenAIRE

    Sridhar, M. S.

    1984-01-01

    Examines the nature and limitations of demand forecasting, discuses plausible methods of forecasting demand for information, suggests some useful hints for demand forecasting and concludes by emphasizing unified approach to demand forecasting.

  17. Trichoepithelioma And Multiple Basal Cell Epithelioma

    Directory of Open Access Journals (Sweden)

    Dey S.K

    1996-01-01

    Full Text Available A combination of multiple trichoepithelioma and basal cell epithelioma is reported. Although malignant degeneration of trichoepithelioma is debated, clinical and histopathological studies, in our case, hint at that. The case is reported for its rarity.

  18. Teaduste akadeemias austati Ahrensit / Allar Viivik

    Index Scriptorium Estoniae

    Viivik, Allar

    2015-01-01

    Eesti Teaduste Akadeemia saalis toimus konverents "Kummardus Ahrensile", sõnavõttude ja ettekannetega anti ülevaade Kuusalu pastori Eduard Ahrensi keelemehetööst. Ettekandega esines ka keelemees Mati Hint

  19. 17 Human Resource Development and the Productivity of the Civil ...

    African Journals Online (AJOL)

    FIRST LADY

    2011-01-18

    Jan 18, 2011 ... Civil Service of Cross River State, Nigeria (Pp. 17-24). Egbe ... knowledge content an employee possesses is the quality of training and retraining the ... offered useful hints that ensured standards that eventually aided the final.

  20. Maximizing your teaching moment

    Science.gov (United States)

    ... may help to give your patient written or audiovisual resources before your meeting. This may help reduce ... As you are teaching, provide reinforcement for learning. Reinforce your ... Offer hints, tips, and strategies that you have gathered ...

  1. Johannes Hindi tütar Pille Pae : inimlik headus ei sõltu režiimist / Pille Pae ; interv. Anneli Ammas

    Index Scriptorium Estoniae

    Pae, Pille

    2006-01-01

    Desintegraatori juhi Johannes Hindi tütar Pille Pae vastab küsimustele, mis puudutavad tema isa armuandmispalve esitamist, isale toetusallkirjade kogumist, Arnold Rüütli suhteid Johannes Hindiga. Lisa: Kes oli Johannes Hint ja mis Desintegraator?

  2. Scattering of highly excited atoms

    International Nuclear Information System (INIS)

    Raith, W.

    1980-01-01

    Experimental methods to excite atomic beams into Rydberg states and the first results of collision experiments with such beams are reported. For further information see hints under relevant topics. (orig.) [de

  3. Impact of hydrogen onboard storage technologies on the performance of hydrogen fuelled vehicles: A techno-economic well-to-wheel assessment

    NARCIS (Netherlands)

    de Wit, M.P.; Faaij, A.P.C.

    2007-01-01

    Hydrogen onboard storage technologies form an important factor in the overall performance of hydrogen fuelled transportation, both energetically and economically. Particularly, advanced storage options such as metal hydrides and carbon nanotubes are often hinted favourable to conventional, liquid

  4. Report on the meeting of the working groups on neutron scattering applied to studying condensed matter, and neutron scattering and complementary methods applied in chemistry and biology

    International Nuclear Information System (INIS)

    1985-06-01

    The present volume consists of 55 lectures. The subjects are: 1) Elastic neutron diffraction, 2) Lattice dynamics, 3) Diffusion, 4) Polymers, 5) Biology, 6) Methods and tools, 7) Magnetism. For distinct papers see hints under relevant topics. (BHO)

  5. Users guide for the ANL IBM SPx

    Energy Technology Data Exchange (ETDEWEB)

    Gropp, W.; Lusk, E.

    1994-12-01

    This guide presents the features of the IBM SPx installed in the Mathematics and Computer Science Division at Argonne National Laboratory. The guide describes the available hardware and software, access policies, and hints for using the system productively.

  6. Kuidas Alfred Adler läks tülli Sigmund Freudiga / Aivar Kull

    Index Scriptorium Estoniae

    Kull, Aivar, 1955-

    1996-01-01

    Arvustus: Adler, Alfred. Inimesetundmine : Inimeste iseloomude peategurid ja nende areng / Tlk. Debora Hint. 2.tr. Tln. : Kupar, 1995. Vaata ka: Kull, Aivar. Kulli pilk. - Tartu : Ilmamaa, 2005, lk. 97-100

  7. Data processing framework for decision making

    DEFF Research Database (Denmark)

    Larsen, Jan

    The aim of the talk is * to provide insight into some of the issues in data processing and detection systems * to hint at possible solutions using statistical signal processing and machine learning methodologies...

  8. Can Biochemistry Usefully Guide the Search for Better Polymer Electrolytes?

    Directory of Open Access Journals (Sweden)

    J. Woods Halley

    2013-09-01

    Full Text Available I review some considerations that suggest that the biochemical products of evolution may provide hints concerning the way forward for the development of better electrolytes for lithium polymer batteries.

  9. Theory of elementary particles. Proceedings

    International Nuclear Information System (INIS)

    Luest, D.; Weigt, G.

    1994-03-01

    These proceedings contain most of the invited talks ans short communications presented at the named symposium. These concern developments in field theory in connection with string models, grand unification, and quantum gravity. See hints under the relevant topics. (HSI)

  10. SPSS for starters

    CERN Document Server

    Cleophas, Ton J

    2010-01-01

    This book contains all statistical tests relevant for starters on SPSS. Each test is explained using a data example from clinical practice along with the main tables of results with an accompanying text with interpretations of the results and hints.

  11. 80th Annual Meeting | Annual Meetings | Events | Indian Academy of ...

    Indian Academy of Sciences (India)

    Current status and future prospects of neutrino mass measurement. View presentation ... Business Meeting of Fellows. 17.00. High Tea ... Hints of 'Beyond Standard Model' cosmology in the cosmic microwave background. View presentation.

  12. evaluation of total annual costs of heat exchanger networks using

    African Journals Online (AJOL)

    user

    after solving the first problem using RPA based heat integration gave a minimum total annual cost (TAC) of $237, ... mathematical programming and non-RPA based Hint software. ... The concept of pinch analysis evolved over the years.

  13. Keeletammik sai järjekordse nimipuu / Kristi Ehrlich

    Index Scriptorium Estoniae

    Ehrlich, Kristi, 1979-

    2009-01-01

    Väike-Maarjas peetud Wiedemanni keelepäevast, kus pidas ettekande ka tänavune keeleauhinna laureaat, Ohio ülikooli professor Ilse Lehiste. Keelekonverentsist võttis osa ka keeleteadlane ja TLÜ emeriitprofessor Mati Hint

  14. An introduction to the theory of linear spaces

    CERN Document Server

    Shilov, Georgi E

    1975-01-01

    Introductory treatment offers a clear exposition of algebra, geometry, and analysis as parts of an integrated whole rather than separate subjects. Numerous examples illustrate many different fields, and problems include hints or answers. 1961 edition.

  15. An introduction to linear algebra and tensors

    CERN Document Server

    Akivis, M A; Silverman, Richard A

    1978-01-01

    Eminently readable, completely elementary treatment begins with linear spaces and ends with analytic geometry, covering multilinear forms, tensors, linear transformation, and more. 250 problems, most with hints and answers. 1972 edition.

  16. F. J. Wiedemanni keeleauhind on lakanud. Elagu F. J. Wiedemanni keeleauhind! / Eevi Ross

    Index Scriptorium Estoniae

    Ross, Eevi

    2003-01-01

    15-ndad ja viimased F. J. Wiedemanni Keeleauhinna Sihtasutuse laureaadid on Mati Hint ja Helju Vals, järgmisel aastal antakse välja esimene riiklik F. J. Wiedemanni keeleauhind Eesti Vabariigi peaministri poolt

  17. Email: pattuquayefio@ug.edu.gh

    African Journals Online (AJOL)

    Apusigah

    making. ... study, the article hints at possible implications of the co-optation of human ... shortage, health challenges such as the Human Immunodeficiency Virus (HIV), and the causes ... appropriate framework for considering such challenges.

  18. Association between intimate partner violence & HIV/AIDS: Exploring the pathways in Indian context

    Directory of Open Access Journals (Sweden)

    Seema Patrikar

    2017-01-01

    Interpretation & conclusions: Significantly higher reporting of HIV/STIs by women experiencing IPV hints at new pathways that link violence and HIV. Further, our analysis showed a high prevalence of IPV in India.

  19. The International Criminal Court: Why We Need It, How We Got It, Our Concern About It

    National Research Council Canada - National Science Library

    MacCuish, Donald A; Hater, David A; Dubriske, Steven D; Ruby, Tomislav

    2005-01-01

    ... extreme. The problem with judicial proceedings is that they can have a hint of victor's justice, especially if the jurisdiction, legitimacy, and authority of the court are not established in advance...

  20. The amateur astronomer

    CERN Document Server

    Moore, Patrick

    2006-01-01

    Introduces astronomy and amateur observing together. This edition includes photographs and illustrations. The comprehensive appendices provide hints and tips, as well as data for every aspect of amateur astronomy. This work is useful for amateur astronomers

  1. Communicating with the Public: Getting It into Print.

    Science.gov (United States)

    Dyal, Donald

    1988-01-01

    Discusses the advantages for libraries of utilizing print media for public information and public relations. News releases, interest stories, and feature stories are described, and hints on writing style for each format and on getting items printed are offered. (MES)

  2. Translations on USSR Military Affairs, Number 1328.

    Science.gov (United States)

    1978-02-02

    of his age. This news came as no surprise to Mikhail Vasil’yevich, and he reported to the commander his readiness immediately to begin the transfer...for this period, in which regard he dropped a hint to the commander. 103 Major Labushev did not take the hint. Convinced that there was no mutual...District. It was directed thence to the garrison judge advocate, who sent Mikhail Vasil’yevich an encouraging letter. It declared that his unit

  3. Generation of Tutorial Dialogues: Discourse Strategies for Active Learning

    Science.gov (United States)

    1998-05-29

    AND SUBTITLE Generation of Tutorial Dialogues: Discourse Strategies for active Learning AUTHORS Dr. Martha Evens 7. PERFORMING ORGANI2ATION NAME...time the student starts in on a new topic. Michael and Rovick constantly attempt to promote active learning . They regularly use hints and only resort...Controlling active learning : How tutors decide when to generate hints. Proceedings of FLAIRS 󈨣. Melbourne Beach, FL. 157-161. Hume, G., Michael

  4. From the standard model to dark matter

    International Nuclear Information System (INIS)

    Wilczek, F.

    1995-01-01

    The standard model of particle physics is marvelously successful. However, it is obviously not a complete or final theory. I shall argue here that the structure of the standard model gives some quite concrete, compelling hints regarding what lies beyond. Taking these hints seriously, one is led to predict the existence of new types of very weakly interacting matter, stable on cosmological time scales and produced with cosmologically interesting densities--that is, ''dark matter''. copyright 1995 American Institute of Physics

  5. Reseach blog:

    DEFF Research Database (Denmark)

    Lieberoth, Andreas

    2011-01-01

    Ongoing research blog discussing Andreas' research in the psychology of applied games, as well as general musings on cognitive neuroscience, game-design, and more. Also contains hints and guides for students on writing psychology research-papers.......Ongoing research blog discussing Andreas' research in the psychology of applied games, as well as general musings on cognitive neuroscience, game-design, and more. Also contains hints and guides for students on writing psychology research-papers....

  6. Towards high-density matter with relativistic heavy-ion collisions

    International Nuclear Information System (INIS)

    Nagamiya, Shoji.

    1990-04-01

    Recent progress in nucleus-nucleus collisions at BNL and CERN suggests a hint that the formation of high-density nuclear matter could be possible with relativistic heavy-ion beams. What is the maximum density that can be achieved by heavy-ion collisions? Are there data which show evidence or hints on the formation of high density matter? Why is the research of high-density interesting? How about the future possibilities on this subject? These points are discussed. (author)

  7. Sense of Accomplishment Is Modulated by a Proper Level of Instruction and Represented in the Brain Reward System.

    Science.gov (United States)

    Nakai, Tomoya; Nakatani, Hironori; Hosoda, Chihiro; Nonaka, Yulri; Okanoya, Kazuo

    2017-01-01

    Problem-solving can be facilitated with instructions or hints, which provide information about given problems. The proper amount of instruction that should be provided for learners is controversial. Research shows that tasks with intermediate difficulty induce the largest sense of accomplishment (SA), leading to an intrinsic motivation for learning. To investigate the effect of instructions, we prepared three instruction levels (No hint, Indirect hint, and Direct hint) for the same insight-problem types. We hypothesized that indirect instructions impose intermediate difficulty for each individual, thereby inducing the greatest SA per person. Based on previous neuroimaging studies that showed involvement of the bilateral caudate in learning and motivation, we expected SA to be processed in this reward system. We recruited twenty-one participants, and investigated neural activations during problem solving by functional magnetic resonance imaging (fMRI). We confirmed that the Indirect hint, which imposed intermediate difficulty, induced the largest SA among the three instruction types. Using fMRI, we showed that activations in the bilateral caudate and anterior cingulate cortex (ACC) were significantly modulated by SA. In the bilateral caudate, the indirect hint induced the largest activation, while the ACC seemed to reflect the difference between correct and incorrect trials. Importantly, such activation pattern was independent of notations (number or letter). Our results indicate that SA is represented in the reward system, and that the Indirect instruction effectively induces such sensation.

  8. Pitfalls and Rewards for Implementing Ocular Motor Testing in Acute Vestibular Syndrome: A Pilot Project.

    Science.gov (United States)

    Dumitrascu, Oana M; Torbati, Sam; Tighiouart, Mourad; Newman-Toker, David E; Song, Shlee S

    2017-03-01

    Isolated acute vestibular syndrome (iAVS) presentations to the emergency department (ED) pose management challenges, given the concerns for posterior circulation strokes. False-negative brain imaging may erroneously reassure clinicians, whereas HINTS-plus examination outperforms imaging to screen for strokes in iAVS. We studied the feasibility of implementing HINTS-plus testing in the ED, aiming to reduce neuroimaging in patients with iAVS. We launched an institutional Quality Improvement initiative, using DMAIC methodology. The outcome measures [proportion of iAVS subjects who had HINTS-plus examinations and underwent neuroimaging by computed tomography/magnetic resonance imaging (CT/MRI)] were compared before and after the established intervention. The intervention consisted of formal training for neurologists and emergency physicians on how to perform, document, and interpret HINTS-plus and implementation of novel iAVS management algorithm. Neuroimaging was not recommended if HINTS-plus suggested peripheral vestibular etiology. If a central process was suspected, brain MRI/MR angiogram was performed. Head CT was reserved only for thrombolytic time-window cases. In the first 2 months postimplementation, HINTS-plus testing performance by neurologists increased from 0% to 80% (P=0.007), and by ED providers from 0% to 9.09% (P=0.367). Head CT scans were reduced from 18.5% to 6.25%. Brain MRI use was reduced from 51.8% to 31.2%. About 60% of the iAVS subjects were discharged from the ED; none were readmitted or had another ED presentation in the ensuing 30 days. Implementation of HINTS-plus evaluation in the ED is valuable and feasible for neurologists, but challenging for emergency physicians. Future studies should determine the "dose-response" curve of educational interventions.

  9. Light weakly interacting massive particles

    Science.gov (United States)

    Gelmini, Graciela B.

    2017-08-01

    Light weakly interacting massive particles (WIMPs) are dark matter particle candidates with weak scale interaction with the known particles, and mass in the GeV to tens of GeV range. Hints of light WIMPs have appeared in several dark matter searches in the last decade. The unprecedented possible coincidence into tantalizingly close regions of mass and cross section of four separate direct detection experimental hints and a potential indirect detection signal in gamma rays from the galactic center, aroused considerable interest in our field. Even if these hints did not so far result in a discovery, they have had a significant impact in our field. Here we review the evidence for and against light WIMPs as dark matter candidates and discuss future relevant experiments and observations.

  10. "Don't know" responses to risk perception measures: implications for underserved populations.

    Science.gov (United States)

    Waters, Erika A; Hay, Jennifer L; Orom, Heather; Kiviniemi, Marc T; Drake, Bettina F

    2013-02-01

    Risk perceptions are legitimate targets for behavioral interventions because they can motivate medical decisions and health behaviors. However, some survey respondents may not know (or may not indicate) their risk perceptions. The scope of "don't know" (DK) responding is unknown. Examine the prevalence and correlates of responding DK to items assessing perceived risk of colorectal cancer. Two nationally representative, population-based, cross-sectional surveys (2005 National Health Interview Survey [NHIS]; 2005 Health Information National Trends Survey [HINTS]), and one primary care clinic-based survey comprised of individuals from low-income communities. Analyses included 31,202 (NHIS), 1,937 (HINTS), and 769 (clinic) individuals. Five items assessed perceived risk of colorectal cancer. Four of the items differed in format and/or response scale: comparative risk (NHIS, HINTS); absolute risk (HINTS, clinic), and "likelihood" and "chance" response scales (clinic). Only the clinic-based survey included an explicit DK response option. "Don't know" responding was 6.9% (NHIS), 7.5% (HINTS-comparative), and 8.7% (HINTS-absolute). "Don't know" responding was 49.1% and 69.3% for the "chance" and "likely" response options (clinic). Correlates of DK responding were characteristics generally associated with disparities (e.g., low education), but the pattern of results varied among samples, question formats, and response scales. The surveys were developed independently and employed different methodologies and items. Consequently, the results were not directly comparable. There may be multiple explanations for differences in the magnitude and characteristics of DK responding. "Don't know" responding is more prevalent in populations affected by health disparities. Either not assessing or not analyzing DK responses could further disenfranchise these populations and negatively affect the validity of research and the efficacy of interventions seeking to eliminate health disparities.

  11. Joint statement by the chairmen of the Standing Committee on Reactors and the Reactor Safety Commission on safety-related documents drawn up under the Franco-German Commission on Safety Questions for Nuclear Installations (DFK). August 29, 1986

    International Nuclear Information System (INIS)

    1986-01-01

    The report contains: 1. The present situation regarding hints and recommendations in the safety declaration by the TUEV Baden on the subject of Cattenom nuclear power station in June 1982. 2. The present situation regarding hints and recommendations in the declaration by the TUEV Rhineland in February 1982 on the subject of radiological aspects and features of the Cattenom site for the nuclear power plant. 3. Answers to press allegations about the safety of Cattenom NPP: scram system, safety cooling system, heat sink for after-heat removal, emergency power supplies, load-follow operation, air crashes, susceptibility to failures. (orig./HP) [de

  12. Performance and optimization of support vector machines in high-energy physics classification problems

    Energy Technology Data Exchange (ETDEWEB)

    Sahin, Mehmet Oezguer; Kruecker, Dirk; Melzer-Pellmann, Isabell [DESY, Hamburg (Germany)

    2016-07-01

    In this talk, the use of Support Vector Machines (SVM) is promoted for new-physics searches in high-energy physics. We developed an interface, called SVM HEP Interface (SVM-HINT), for a popular SVM library, LibSVM, and introduced a statistical-significance based hyper-parameter optimization algorithm for the new-physics searches. As example case study, a search for Supersymmetry at the Large Hadron Collider is given to demonstrate the capabilities of SVM using SVM-HINT.

  13. Bs Physics at LEP, SLD, and CDF Delta m_s and Delta Gamma_s

    CERN Document Server

    Boix, G

    2001-01-01

    The current status of the experimental knowledge of $\\Bs$ meson physics is reviewed. Results from LEP and CDF on the width difference $\\dgs$ are presented, the corresponding average is found to be in good agreement with the present theoretical estimation. The $\\Bs$ oscillations have not yet been resolved, despite the progress recently achieved by SLD and ALEPH. The world combination, including results from the LEP experiments, SLD and CDF, is presented, together with the expected and observed lower limit on the $\\Bs$ oscillation frequency. A tantalizing hint of an oscillation is observed around $\\dms\\sim17 \\psin$, near future results could increase the significance of this hint.

  14. Üks vormiõpetus (I) : Vaimumõõgad / Henn Saari

    Index Scriptorium Estoniae

    Saari, Henn, 1924-1999

    1998-01-01

    Diskussioonist eesti nüüdiskeele võrmiõpetuse ning selle eelduseks oleva fooniasüsteemi üle uut õigekeelsussõnaraamatut ette valmistades. Vt. ka: Ehala, Martin. Eesti morfoloogia olemus // Keel ja Kirjandus, 1997, nr. 6 ; Hint, Mati. Eesti foneetika möödunud hiilgus ja möödumata viletsus // Keel ja Kirjandus, 1997, nr. 2 ; Ross, Kristiina. Eesti morfo(fono)loogia põnevamad probleemid : EKG contra Mati Hint // Keel ja Kirjandus, 1997, nr. 5

  15. MHD equilibrium of heliotron J plasmas

    International Nuclear Information System (INIS)

    Suzuki, Yasuhiro; Nakamura, Yuji; Kondo, Katsumi; Nakajima, Noriyoshi; Hayashi, Takaya

    2004-01-01

    MHD equilibria of Heliotron J plasma are investigated by using HINT code. By assuming some profiles of the current density, effects of the net toroidal currents on the magnetohydrodynamics (MHD) equilibrium are investigated. If the rotational transform can be controlled by the currents, the generation of good flux surfaces is expected. In order to study equilibria with self-consistent bootstrap current, the boozer coordinates are constructed by converged HINT equilibrium as a preliminary study. Obtained spectra are compared with ones of VMEC code and both results are consistent. (author)

  16. Screen-Capturing System with Two-Layer Display for PowerPoint Presentation to Enhance Classroom Education

    Science.gov (United States)

    Lai, Yen-Shou; Tsai, Hung-Hsu; Yu, Pao-Ta

    2011-01-01

    This paper proposes a new presentation system integrating a Microsoft PowerPoint presentation in a two-layer method, called the TL system, to promote learning in a physical classroom. With the TL system, teachers can readily control hints or annotations as a way of making them visible or invisible to students so as to reduce information load. In…

  17. Teaching Environmental Ethics: Moral Considerations and Legislative Action

    Science.gov (United States)

    McGowan, Richard J.; Buttrick, Hilary G.

    2017-01-01

    As one of the first business ethics textbook states, by way of observation, "Custom, convention and the accepted courtesies of a society are not the foundation of ethics even though they provide valuable hints as to what men think… Law enshrines many of the ethical judgments of a society, but it is not coextensive with ethics" (Garrett,…

  18. BOOK REVIEWS BOEKRESE SIES

    African Journals Online (AJOL)

    under consideration, and tbe error simply annoys the medical reader. There is a hint of .... In the last analysis what both doctor and patient want to know is the diagnosis ... is the armour of education adequate to arouse curiosity in the common ...

  19. A climatological study of the relations among solar activity, galactic ...

    Indian Academy of Sciences (India)

    Though correlation study between precipitation and other parameters do not hint any linear relation, still the Fourier and wavelet analyses give an idea of common periodicities. The 9–11 year periodicity of sunspot numbers calculated by Fourier transform is also confirmed by wavelet transform in annual scale. Similarly ...

  20. Analysis of the primary source term for meltdown accidents using MELCOR 1.8.2; Analyse des primaeren Quellterms bei Kernschmelzunfaellen mit MELCOR 1.8.2

    Energy Technology Data Exchange (ETDEWEB)

    Schmuck, P.

    1995-08-01

    The MELCOR code describing accident phenomena in the core and primary systems was used for source term calculations and - in the context of the MELCOR Cooperative Assessment Programme - for studying two-phase flows through components such as valves and chokes. Results of the latter studies in comparison to experiments gave hints for an improved calculation of momentum transfer between the phases. (orig.)

  1. Analysis of the primary source term for meltdown accidents using MELCOR 1.8.2

    International Nuclear Information System (INIS)

    Schmuck, P.

    1995-01-01

    The MELCOR code describing accident phenomena in the core and primary systems was used for source term calculations and - in the context of the MELCOR Cooperative Assessment Programme - for studying two-phase flows through components such as valves and chokes. Results of the latter studies in comparison to experiments gave hints for an improved calculation of momentum transfer between the phases. (orig.)

  2. Moskvalased näevad eesti nüüdiskunsti / Johannes Saar

    Index Scriptorium Estoniae

    Saar, Johannes, 1965-

    2007-01-01

    Moskvas nüüdiskunsti keskuses avatakse 19.09.2007 eesti kunstnike grupinäitus "Tagurpidi bluus". Anna Hints, Laura Kuusk, Neeme Külm, Kristina Norman, Jüri Ojaver, Jaan Paavle, Jaan Toomik ja Paul Rodgers pakuvad videos, fotos ja installatsioonides mõtlemisainet kultuurilise konsensuse üle. Näituse korraldaja on Kaasaegse Kunsti Eesti Keskus

  3. Coping Styles with Student Misbehavior as Mediators of Teachers' Classroom Management Strategies

    Science.gov (United States)

    Tran, Van Dat

    2016-01-01

    The purpose of the present study is to identify how teachers' use of various coping styles with student misbehavior, and the extent to which these relate to their classroom management techniques -- punishment, recognition and reward, hinting, discussion, and aggression. It examines data from 397 junior high school teachers in Vietnam. The results…

  4. Shoptalk: A Column of Brief Ideas and Sundry Thoughts about Media and Teaching English.

    Science.gov (United States)

    Donelson, Kenneth L., Ed.

    1970-01-01

    Practical advice is provided by Arizona high School English teachers on such areas of media usage as lettering for media projects, hints on movie-making, uses for instamatic cameras and slides, and the use of media for units on propaganda, oral communication, and composition. (MF)

  5. Constraints on the neutrino emission from the Galactic Ridge with the ANTARES telescope

    NARCIS (Netherlands)

    Adrián-Martínez, S.; Albert, A.; André, M.; Anghinolfi, M.; Anton, G.; Ardid, M.; Aubert, J.-J.; Avgitas, T.; Baret, B.; Barrios-Martí, J.; Basa, S.; Bertin, V.; Biagi, S.; Bormuth, R.; Bouwhuis, M.C.; Bruijn, R.; Brunner, J.; Busto, J.; Capone, A.; Caramete, L.; Carr, J.; Celli, S.; Chiarusi, T.; Circella, M.; Coleiro, A.; Coniglione, R.; Costantini, H.; Coyle, P.; Creusot, A.; Deschamps, A.; De Bonis, G.; Distefano, C.; Donzaud, C.; Dornic, D.; Drouhin, D.; Eberl, T.; El Bojaddaini, I.; Elsässer, D.; Enzenhöfer, A.; Fehn, K.; Felis, I.; Fusco, L.A.; Galatà, S.; Gay, P.; Geißelsöder, S.; Geyer, K.; Giordano, V.; Gleixner, A.; Glotin, H.; Gracia-Ruiz, R.; Graf, K.; Hallmann, S.; van Haren, H.; Heijboer, A.J.; Hello, Y.; Hernández-Rey, J.J.; Hößl, J.; Hofestädt, J.; Hugon, C.; Illuminati, C.; James, C.W.; de Jong, M.; Kadler, M.; Kalekin, O.; Katz, U.; Kießling, D.; Kouchner, A.; Kreter, M.; Kreykenbohm, I.; Kulikovskiy, V.; Lachaud, C.; Lahmann, R.; Lefèvre, D.; Leonora, E.; Loucatos, S.; Marcelin, M.; Margiotta, A.; Marinelli, A.; Martínez-Mora, J.A.; Mathieu, A.; Michael, T.; Migliozzi, P.; Moussa, A.; Mueller, C.; Nezri, E.; Păvălaş, G.E.; Pellegrino, C.; Perrina, C.; Piattelli, P.; Popa, V.; Pradier, T.; Racca, C.; Riccobene, G.; Roensch, K.; Saldaña, M.; Samtleben, D.F.E.; Sánchez-Losa, A.; Sanguineti, M.; Sapienza, P.; Schnabel, J.; Schüssler, F.; Seitz, T.; Sieger, C.; Spurio, M.; Stolarczyk, T.; Taiuti, M.; Trovato, A.; Tselengidou, M.; Turpin, D.; Tönnis, C.; Vallage, B.; Vallée, C.; Van Elewyck, V.; Visser, E.; Vivolo, D.; Wagner, S.; Wilms, J.; Zornoza, J.D.; Zúñiga, J.

    A highly significant excess of high-energy astrophysical neutrinos has been reported by the IceCube Collaboration. Some features of the energy and declination distributions of IceCube events hint at a North/South asymmetry of the neutrino flux. This could be due to the presence of the bulk of our

  6. "Telling Tales": The Teaching of American History through Storytelling

    Science.gov (United States)

    Sanchez, Tony R.; Mills, Randy K.

    2005-01-01

    The late novelist Walker Percy once argued that literature, especially fictional stories, has portrayed a clearer and far more cohesive picture of the human condition than any of the social sciences, including history. His ideas hint at the possibility of conceptualizing the American experience as the story that it is and as a way of organizing…

  7. A New Kind of Biomaterials-Bullfrog Skin Collagen

    Institute of Scientific and Technical Information of China (English)

    He LI; Bai Ling LIU; Hua Lin CHEN; Li Zhen GAO

    2003-01-01

    Pepsin-soluble collagen was prepared from bullfrog skin and partially characterized. This study revealed interesting differences, such as molecular weight, amino acid composition, denaturation temperature (Td), in the frog skin collagen when compared to the known vertebrate collagens. This study gives hints that bullfrog skin can be a potential, safe alternative source of collagen from cattle for use in various fields.

  8. Gamification for low-literates: Findings on motivation, user experience, and study design

    NARCIS (Netherlands)

    Schouten, Dylan; Pfab, Isabel; Cremers, Anita; van Dijk, Elisabeth M.A.G.; Neerincx, Mark; Miesenberger, Klaus; Fels, Deborah; Archambault, Dominique; Penaz, Petr; Zagler, Wolfgang

    This study investigated the effects of the gamification elements of scaffolding, score and hints on the user enjoyment and motivation of people of low literacy. In a four-condition within-subjects experiment, participants performed mental spatial ability tests with the aforementioned elements.

  9. Learning to See History: A Content Analysis of the Affordances of Graphic Novels for High School Teaching

    Science.gov (United States)

    Boerman-Cornell, William

    2012-01-01

    Recent studies of graphic novels (book-length fiction or non-fiction narratives that employ the conventions of comic books to convey meaning) and multimodality have hinted that graphic novels (GNs) might offer a great deal of meaning-making potential to readers. Some studies have argued that graphic novels could be useful for English Language…

  10. Study of an ep facility for Europe

    International Nuclear Information System (INIS)

    Amaldi, U.

    1979-08-01

    These proceedings contains the lectures and discussion held in the named meeting. These concern machine problems, superconducting magnets, the search of new currents and new particles, large q 2 physics and hadron structure, small q 2 physics and photoproduction, as well as detectors for charged and neutral current events. See hints under the relevant topics. (HSI)

  11. GSI-contributions to HCI-92

    International Nuclear Information System (INIS)

    1992-11-01

    This preprint comprises all the papers presented at the VIth International Conference on the Physics of Highly Charged Ions (Manhattan, Kansas, September 28 - October 2, 1992) reporting on results from experiments performed at the GSI heavy ion accelerator facilities. See hints under the relevant topics. (orig./HSI)

  12. Ask-Elle: an adaptable programming tutor for Haskell giving automated feedback

    NARCIS (Netherlands)

    Gerdes, Alex; Heeren, Bastiaan; Jeuring, J.T.; Binsbergen, Thomas van

    2015-01-01

    Ask-Elle is a tutor for learning the higher-order, strongly-typed functional programming language Haskell. It supports the stepwise development of Haskell programs by verifying the correctness of incomplete programs, and by providing hints. Programming exercises are added to Ask-Elle by providing a

  13. Model solutions and properties for diagnosing student programs in Ask-Elle

    NARCIS (Netherlands)

    Jeuring, Johan; Binsbergen, Thomas~van; Gerdes, Alex; Heeren, Bastiaan

    2014-01-01

    Ask-Elle is an interactive tutor that supports the stepwise development of simple functional programs. Using Ask-Elle students receive feedback about whether or not they are on the right track, they can ask for a hint when they are stuck, and get suggestions about how to refactor their program. Our

  14. Ask-Elle: an Adaptable Programming Tutor for Haskell Giving Automated Feedback

    NARCIS (Netherlands)

    Gerdes, A.; Heeren, B.J.; Jeuring, J.T.; Binsbergen, Thomas~van

    2017-01-01

    Ask-Elle is a tutor for learning the higher-order, strongly-typed functional programming language Haskell. It supports the stepwise development of Haskell programs by verifying the correctness of incomplete programs, and by providing hints. Programming exercises are added to Ask-Elle by providing a

  15. Act Quickly! Seconds Count! Second Edition.

    Science.gov (United States)

    Ogden, Bob; Hayter, Roy, Ed.

    This booklet is designed to help hotel employees know what to do if a fire breaks out in the hotel. It also gives hints and suggestions that will help employees to reduce the risk of a fire occurring. Topics are as follows: an employee's responsibility if a fire breaks out; procedures to follow in the event of fire; mapping fire exits and escape…

  16. Filmiankeet

    Index Scriptorium Estoniae

    1986-01-01

    Vastavad M. Balbat, Õ. Orav, L. Priimägi, T. Kallas, P. Simm, A. Valton, J. Ruus, S. Školnikov, K. Tamberg, I. Unt, P. Simm, T. Elmanovitš, M. Hint, V. Kalda, R. Karemäe, K. Komissarov, V. Kuik, M. Kõiv, E. Link, L. Kärk, A. Lõhmus, J. Lõhmus ja T. Merisalu

  17. Searching for Variables and Models to Investigate Mediators of Learning from Multiple Representations

    Science.gov (United States)

    Rau, Martina A.; Scheines, Richard

    2012-01-01

    Although learning from multiple representations has been shown to be effective in a variety of domains, little is known about the mechanisms by which it occurs. We analyzed log data on error-rate, hint-use, and time-spent obtained from two experiments with a Cognitive Tutor for fractions. The goal of the experiments was to compare learning from…

  18. Understanding reading problems in secondary schools: Some ...

    African Journals Online (AJOL)

    ... factors are discussed based on the evidence obtained by observations and research findings. The importance of teaching reading 'as a subject in the secondary school is hinted. Recommendations are made to ensure that reading as a tool to learning is given a prominent place in schools and libraries throughout Nigeria ...

  19. Fermentation: From Sensory Experience to Conceptual Understanding

    Science.gov (United States)

    Moore, Eugene B.

    1977-01-01

    Presented is a laboratory exercise that utilizes the natural yeast carbonation method of making homemade root beer to study fermentation and the effect of variables upon the fermentation process. There are photographs, a sample data sheet, and procedural hints included. (Author/MA)

  20. User Interface Design for Dynamic Geometry Software

    Science.gov (United States)

    Kortenkamp, Ulrich; Dohrmann, Christian

    2010-01-01

    In this article we describe long-standing user interface issues with Dynamic Geometry Software and common approaches to address them. We describe first prototypes of multi-touch-capable DGS. We also give some hints on the educational benefits of proper user interface design.

  1. Linear algebra

    CERN Document Server

    Shilov, Georgi E

    1977-01-01

    Covers determinants, linear spaces, systems of linear equations, linear functions of a vector argument, coordinate transformations, the canonical form of the matrix of a linear operator, bilinear and quadratic forms, Euclidean spaces, unitary spaces, quadratic forms in Euclidean and unitary spaces, finite-dimensional space. Problems with hints and answers.

  2. User modelling for motivational systems : the affective and the rational routes to persuasion

    NARCIS (Netherlands)

    Grasso, F.; Ham, J.R.C.; Masthoff, J.F.M.

    2011-01-01

    The idea that a computer system could be used to motivate people to perform a certain task on the basis of a user model is certainly not novel. As early as the 80s, intelligent tutoring systems would encourage students to learn by means of tailored feedback and hints [24], and in the 90s patient

  3. Environmental policy and environmental protection

    International Nuclear Information System (INIS)

    1980-01-01

    The political, economic, scientific and international dimensions of the subject are discussed with a view to teaching at school. To get a better picture, there is no division between the information section and the didactic part. The didactic part contains full-text examples and hints for their use in teaching. (HP) [de

  4. Intentionality, consciousness, and creating community.

    Science.gov (United States)

    Malinski, Violet M

    2009-01-01

    Intentionality is briefly explored from the perspective of seminal written works on therapeutic touch and recorded conversations with Martha E. Rogers. This overview hints at possible interrelationships among intentionality, consciousness, and creating community, along with conceptual ambiguities, which are explored in detail by Zahourek and Larkin in this column.

  5. Heisenberg and Ferromagnetism

    Indian Academy of Sciences (India)

    how Heisenberg identified the quantum mechan- ical exchange ... condensed matter physics from the Indian ... electrons per atom and 'm,' is the electronic mass. Dia- magnetism is .... what is the origin of this ordering field Hint = aM, that gives rise to a ... the case with magnetism, where the fundamental Inech- anism for the ...

  6. Fulltext PDF

    Indian Academy of Sciences (India)

    2National Centre for Radio Astrophysics, Tata Institute of Fundamental Research, ... high-redshift—cosmology: miscellaneous—elementary particles. .... may provide a hint about its origin. ..... Within conventional physics the corrections to ... One interesting possibility is the presence of a very low mass background pseudo-.

  7. Star-Triangle Relation of the Chiral Potts Model Revisited

    OpenAIRE

    Horibe, M.; Shigemoto, K.

    2001-01-01

    We give the simple proof of the star-triangle relation of the chiral Potts model. We also give the constructive way to understand the star-triangle relation of the chiral Potts model, which may give the hint to give the new integrable models.

  8. An Analysis of Young Students' Thinking When Completing Basic Coding Tasks Using Scratch Jnr. on the iPad

    Science.gov (United States)

    Falloon, G.

    2016-01-01

    Recent government moves in many countries have seen coding included in school curricula, or promoted as part of computing, mathematics or science programmes. While these moves have generally been associated with a need to engage more young people in technology study, research has hinted at possible benefits from learning to program including…

  9. Letters of Stone. From Nazi Germany to South Africa. Steven Robins ...

    African Journals Online (AJOL)

    merely hint at the gruesome reality in Nazi Germany. With the hindsight granted to present-day readers, we know the fate that awaited these men and women as an elongated and agonising social death reached its culmination in systematic mass murder. In describing his journeys to Germany,. Poland, Israel and the United ...

  10. Linear response theory applied to the computation of multi-differential cross sections in deep inelastic reactions

    International Nuclear Information System (INIS)

    Ngo, C.

    1978-01-01

    Correlations between observable quantities in deep inelastic reactions, which are observed through multidifferential cross sections measurements, provide a severe test for the models by making strong constraints. Nevertheless these multicorrelated measurements provide hints for the physical features which they have to take into account. (orig.) [de

  11. Anneteparaad III / Karin Paulus

    Index Scriptorium Estoniae

    Paulus, Karin, 1975-

    2008-01-01

    Tutvustatakse Tartu Kõrgema Kunstikooli diplomandide lõputöid: 1. Diana Hints "Ba-Rokk", 2. Maire Rebina "Alleshoitud naeratused", 3. Liis Pihlik "Unistused ehk hingele pai", 4. Ille Agu "Pitsiring - pruudipesu kollektsioon", 5. Ingwald Koser "Chaise Longue", 6. Kaisa Paluoja installatsioon "/....../", 7. Kaidi Ploomipuu arvutiga juhitavatel telgedel kootud sisustuskangas

  12. Feeding Your 4- to 7-Month-Old

    Science.gov (United States)

    ... check with your doctor before giving any solid foods. Is My Baby Ready to Eat Solids? How can you tell if your baby is ready for solids? Here are a few hints: Is your baby's tongue-thrust ... causes them to push food out of their mouths. Can your baby support ...

  13. Res Publica v respublike / Roman Gornev

    Index Scriptorium Estoniae

    Gornev, Roman

    2002-01-01

    Järg 29. november nr. 48 lk. 7. Res Publica - uue poliitika partei. Res Publica Ida-Virumaal, partei juhtfiguurid, Res Publica Kohtla-Järvel. Koalitsioonileping Keskerakonnaga viis konfliktini partei juhtkonnaga. Kohtla-Järve Res Publica kohaliku organisatsiooni konflikti partei juhtkonnaga kommenteerib Hants Hint

  14. Science.gov: gateway to government science information.

    Science.gov (United States)

    Fitzpatrick, Roberta Bronson

    2010-01-01

    Science.gov is a portal to more than 40 scientific databases and 200 million pages of science information via a single query. It connects users to science information and research results from the U.S. government. This column will provide readers with an overview of the resource, as well as basic search hints.

  15. Effects of a Progressive Prompting-Based Educational Game on Second Graders' Mathematics Learning Performance and Behavioral Patterns

    Science.gov (United States)

    Yang, Kai-Hsiang; Chu, Hui-Chun; Chiang, Li-Yu

    2018-01-01

    Game-based learning (GBL) has been proven to be an attractive learning model by many studies; however, scholars have pointed out that the effectiveness of game-based learning could be limited if proper learning strategies are not incorporated. Prompting is a strategy that plays the important role of providing hints and guidance in interactive…

  16. Careers in Online: Want Ads in the Online Industry.

    Science.gov (United States)

    Dolan, Donna R.; Hoffman, Laura J.

    1984-01-01

    Describes sources of job listings in online industry including "New York Times,""Boston Globe,""Washington Post,""Los Angeles Times,""Wall Street Journal,""National Business Employment Weekly," and hints on methods for reading and responding to ads and placing them. Sample advertisements…

  17. 3D protein-structure-oriented discovery of clinical relation across chronic lymphocytic leukemia patients

    DEFF Research Database (Denmark)

    Mochament, Konstantinos; Agathangelidis, Andreas; Polychronidou, Eleftheria

    2017-01-01

    Chronic lymphocytic leukemia (CLL) is the most common adult leukemia with still unclear etiology. Indications of antigenic pressure have been hinted, using sequence and structure-based reasoning. The accuracy of such approaches, and in particular of the ones derived from 3D models obtained from t...

  18. Electroweak couplings of the lepton

    Indian Academy of Sciences (India)

    magnetic and electric dipole moments of the tau have been performed. ... pressing issue in particle physics today, a truly satisfactory theory of mass should be ex- .... structure of the universe, and may well turn out to be a valuable hint in our ...

  19. Environmental law

    International Nuclear Information System (INIS)

    Bender, B.; Sparwasser, R.

    1988-01-01

    Environmental law is discussed exhaustively in this book. Legal and scientific fundamentals are taken into account, a systematic orientation is given, and hints for further information are presented. The book covers general environmental law, plan approval procedures, protection against nuisances, atomic law and radiation protection law, water protection law, waste management law, laws on chemical substances, conservation law. (HSCH) [de

  20. Kernforschungsanlage Juelich, Institut fuer Kernphysik: Annual report 1983

    International Nuclear Information System (INIS)

    Baur, G.; Mayer-Boericke, C.; Schult, O.; Seyfarth, H.; Speth, J.; Turek, P.

    1984-04-01

    This annual report contains extended abstracts of the work performed at the named institute together with a list of publications. The abstracts deal with nuclear reactions, nuclear spectroscopy, atomic collisions, solar energy, and technical developments. See hints under the relevant topics. (HSI) [de

  1. High energy physics and nuclear structure

    International Nuclear Information System (INIS)

    Measday, D.F.; Thomas, A.W.

    1980-01-01

    These proceedings contain the papers presented at the named conference. These concern eletromagnetic interactions, weak interactions, strong interactions at intermediate energy, pion reactions, proton reactions, strong interactions at high energy, as well as new facilities and applications. See hints under the relevant topics. (HSI)

  2. Vector and parallel processors in computational science

    International Nuclear Information System (INIS)

    Duff, I.S.; Reid, J.K.

    1985-01-01

    These proceedings contain the articles presented at the named conference. These concern hardware and software for vector and parallel processors, numerical methods and algorithms for the computation on such processors, as well as applications of such methods to different fields of physics and related sciences. See hints under the relevant topics. (HSI)

  3. Instructional Exchange. Volume 2, Number 1-6, September 1990-March 1991.

    Science.gov (United States)

    Serafin, Ana Gil, Ed.

    1991-01-01

    This document consists of six issues of a newsletter that provides a forum for the sharing of research findings and instructional strategies by faculty of Western Michigan University. Issue Number 1 addresses writing in the Writing Across the Curriculum Program with notification of a faculty workshop, hints on how to encourage good writing, and a…

  4. Pink Frilly Dresses and the Avoidance of All Things "Girly": Children's Appearance Rigidity and Cognitive Theories of Gender Development

    Science.gov (United States)

    Halim, May Ling; Ruble, Diane N.; Tamis-LeMonda, Catherine S.; Zosuls, Kristina M.; Lurye, Leah E.; Greulich, Faith K.

    2014-01-01

    Many young children pass through a stage of gender appearance rigidity; girls insist on wearing dresses, often pink and frilly, whereas boys refuse to wear anything with a hint of femininity. In 2 studies, we investigated the prevalence of this apparent hallmark of early gender development and its relation to children's growing identification with…

  5. Form factors and charge radii in a quantum chromodynamics ...

    Indian Academy of Sciences (India)

    ... parent compared to the linear parent. Also, the analysis leads to a lower as well as upper bounds on the four-momentum transfer 2, hinting at a workable range of 2 within this approach, which may be useful in future experimental analyses. Comparison of both the options shows that the linear parent is the better option.

  6. Suurimad toetajad külas / Toivo Olvi

    Index Scriptorium Estoniae

    Olvi, Toivo

    2003-01-01

    11. VII külastasid Inju lastekodu mõisa ehitaja ja omaniku Hermann von Krause järeltulijad. Wolfgang ja Riccarda von Mecklenburg toetasid tänavu lastekodu renoveerimist 10000 euroga. Lühtri ostmiseks annetas raha Mati Hint. Lastekodu finantseerimisest

  7. International conference on fifty years research in nuclear fission

    International Nuclear Information System (INIS)

    1989-02-01

    These proceedings contain extended abstracts of the papers presented at the named conference. They deal with static properties of fission, instrumentation for fission studies, fission in compound-nucleus reactions, fission dynamics, fission-like heavy ion reactions, and fusion reactions. See hints under the relevant topics. (HSI)

  8. Beyond the Investment Narrative

    Science.gov (United States)

    Moss, Peter

    2013-01-01

    The current policy interest in early childhood education and care is driven by an investment narrative, a story of quality and high returns emerging from a dominant neoliberal political economy. This short note expresses deep reservations about this narrative, and hints at another narrative that foregrounds democracy, experimentation and…

  9. α-Monitor(roating drum cell) - an in-line instrument for continuous measuring α-activity

    International Nuclear Information System (INIS)

    Groll, P.; Brenk, O.; Guettle, G.; Persohn, M.; Radek, S.; Roeder, L.; Roemer, J.

    1982-03-01

    In this report the documentation for the installation of the α-monitor in a reprocessing facility is given. The mechanics of the apparatus is described as well as the electronics. In detail the conditions for normal operation and hints for trouble-shooting are given. (orig.) [de

  10. Heating with wood. An advisor for a correct and clean heating; Heizen mit Holz. Ein Ratgeber zum richtigen und sauberen Heizen

    Energy Technology Data Exchange (ETDEWEB)

    Behnke, Anja [Umweltbundesamt, Dessau (Germany); Kemper, Bernd-Michael [Landesanstalt fuer Umwelt, Messungen und Naturschutz Baden-Wuerttemberg (LUBW), Karlsruhe (Germany)

    2010-02-15

    Correctly used, wood is an environmental-friendly fuel. With well prepared wood, the wood furnace or wood boiler provides for comfortable warmth and does not load the environment too much. The brochure under consideration gives hints, how a wood heating is to be operated correctly.

  11. Towards rare-earth-ion-doped Al2O3 active integrated optical devices

    OpenAIRE

    Ay, F.; Bradley, J.; Worhoff, Kerstin; Pollnau, Markus

    2007-01-01

    Aluminum oxide planar waveguides with low loss (0.11 dB/cm at 1523 nm) are fabricated. Channel waveguides are obtained by reactive ion etching. Erbium-doped layers show no upconversion luminescence, a hint that ion clustering is small.

  12. No nuclear safety without security

    International Nuclear Information System (INIS)

    Anon.

    2016-01-01

    ead of Health and Safety - Nuclear Safety and Corporate Security at ENGIE Benelux, Pierre Doumont has the delicate job of defining and implementing measures, including cybersecurity, to prevent the risk of malevolent acts against tangible and intangible assets. He gives some hints on the contribution of nuclear security to safety.

  13. Einstein Gravity Explorer–a medium-class fundamental physics mission

    NARCIS (Netherlands)

    Schiller, S.; Tino, G.M.; Gill, E.

    2008-01-01

    The Einstein Gravity Explorer mission (EGE) is devoted to a precise measurement of the properties of space-time using atomic clocks. It tests one of the most fundamental predictions of Einstein’s Theory of General Relativity, the gravitational redshift, and thereby searches for hints of quantum

  14. World Radio and TV Handbook. A Complete Directory of International Radio and Television. Twenty-Seventh Edition. 1973.

    Science.gov (United States)

    Frost, J. M., Ed.

    This handbook provides detailed information about broadcasting and international broadcasting organization. It lists Esperanto programs, English language news programs from foreign countries, religious broadcasting organizations, and gives hints to improve broadcast reception. The main entry section gives a detailed description of radio stations…

  15. Possibilities of mathematical models in solving flow problems in environmental protection and water architecture

    Energy Technology Data Exchange (ETDEWEB)

    1979-01-01

    The booklet presents the full text of 13 contributions to a Colloquium held at Karlsruhe in Sept. 1979. The main topics of the papers are the evaluation of mathematical models to solve flow problems in tide water, seas, rivers, groundwater and in the earth atmosphere. See further hints under relevant topics.

  16. Battle of the quarks

    CERN Multimedia

    Cho, A

    2001-01-01

    The search for QGP has sparked a war of words between rival physicists in the US and Europe. Researchers from Brookhaven reported that RHIC had show intriguing hints that it could be making the plasma. Researchers at CERN though stand by their claim that the SPS already makes the stuff (1 page).

  17. Investment horizons : A time-dependent measure of asset performance

    OpenAIRE

    Ingve Simonsen; Anders Johansen; Mogens H. Jensen

    2005-01-01

    We review a resent {\\em time-dependent} performance measure for economical time series -- the (optimal) investment horizon approach. For stock indices, the approach shows a pronounced gain-loss asymmetry that is {\\em not} observed for the individual stocks that comprise the index. This difference may hint towards an synchronize of the draw downs of the stocks.

  18. The Right Time to Start Writing

    Science.gov (United States)

    Casa, Tutita M.

    2015-01-01

    Communication has long been emphasized in standards-based instruction (NCTM 1991; 2000), yet little distinction has been made between oral and written forms. Nonetheless, both the mathematics and the English language arts Common Core State Standards (CCSS) documents continue to hint at the importance of writing mathematically (CCSSI 2010). The…

  19. Filmil on Sõpruse kinos kohtumine - ta kohtub fotoga

    Index Scriptorium Estoniae

    2011-01-01

    Eesti esimesest fotofilmide festivalist 14. okt.-l Tallinnas kinos Sõprus, tutvustavad kuraatorid Anna Hints ja Alis Mäesalu. Lühidalt eesti fotofilmi ajaloost, rahvusvahelisest fotofimide konkursist "Ajatu lugu". Seminaril ettekanded Liina Siibilt ja Gusztáv Hámosilt (Saksamaa)

  20. Do micro brown dwarf detections explain the galactic dark matter?

    NARCIS (Netherlands)

    Nieuwenhuizen, T.M.; Schild, R.E; Gibson, C.H.

    2011-01-01

    The baryonic dark matter dominating the structures of galaxies is widely considered as mysterious, but hints for it have been in fact detected in several astronomical observations at optical, infrared, and radio wavelengths. We call attention to the pattern of star formation in a galaxy merger, the

  1. On the role of doping in High-Tc superconductors

    International Nuclear Information System (INIS)

    Mei, C.; Smith, V.H. Jr.

    1994-01-01

    High-T c superconductors (HTSCS) are usually obtained by doping electron donors or acceptors into parent materials. The actual role played by doping is still uncertain with various interpretations. The present electronic structure study provides some hints which may help to solve the mystery

  2. Lilleilu rehe all / Elvi Nassar

    Index Scriptorium Estoniae

    Nassar, Elvi

    2009-01-01

    Näitus "Lillemotiiv moevormil" Eesti Vabaõhumuuseumis Pulga talu rehe all. Näitusel oli väljas paarkümmend fliseliini ja paberisse liimitud-vormitud-kägardatud kleiti. Muuseumi töötoas tutvustas pakutrüki- ja origamitehnikat jaapani disainer Yumiko Okazaki. Osalesid Anu Hint, Anne Metsis, Monika Kisand, Juta Piirlaid

  3. An Expert System-based Context-Aware Ubiquitous Learning Approach for Conducting Science Learning Activities

    Science.gov (United States)

    Wu, Po-Han; Hwang, Gwo-Jen; Tsai, Wen-Hung

    2013-01-01

    Context-aware ubiquitous learning has been recognized as being a promising approach that enables students to interact with real-world learning targets with supports from the digital world. Several researchers have indicated the importance of providing learning guidance or hints to individual students during the context-aware ubiquitous learning…

  4. Our Documents: A National Initiative on American History, Civics, and Service. Teacher Sourcebook, Volume II

    Science.gov (United States)

    Mazzenga, Maria, Ed.; McCullough, Julie, Ed.

    2003-01-01

    What do Matthew Brady, Carrie Chapman Catt, Ansel Adams, Orson Welles, and J. Howard Miller have to do with the 100 milestone documents? A few hints: Matthew Brady created the first photographic documentation of a war. Carrie Chapman Catt was the president of the National American Woman Suffrage Association in 1920. Orson Welles produced plays for…

  5. In search of high density collective phenomena in nuclear collision

    International Nuclear Information System (INIS)

    Gyulassy, M.

    1979-06-01

    The progress made toward uncovering signatures of collective phenomena is reviewed. Elements of the basic reaction mechanism leading to a complex background are first discussed. Possible hints of collective phenomena in proton and pion single and double inclusive spectra as well as π - multiplicity data are then described. 6 figures, 2 tables

  6. Download this PDF file

    African Journals Online (AJOL)

    Information Technology

    continuation of traditional practices in the design of new general-purpose dic- tionaries which were published within this period, the increasingly central role of the computer in dictionary work, and the negative effects computerization is having on lexicography as "industry". Why the change in title? The author hints at an ...

  7. The behavioural response of the professional buyer on social cues from the vendor and how to measure it

    NARCIS (Netherlands)

    van Zeeland-van der Holst, Eveline Maria; Henseler, Jörg

    2018-01-01

    Purpose Vendors’ social cues ─ physical or behavioural hints ─ have an impact on the professional buyer. However, little is known about that impact. The purpose of this paper is to place knowledge about the impact of social cues that other disciplines acquired in the context of B2B marketing in

  8. The 100 Best Targets for Astrophotography

    CERN Document Server

    Kier, Ruben

    2009-01-01

    Reveals, for each month of the year, the choicest celestial treasures within the reach of a commercial CCD camera. This book includes hints and advice on framing, exposures, and filters. It focuses on what northern latitude objects to image at any given time of the year to get the most spectacular results

  9. Moving the Borders: Multiculturalism and Global Citizenship in the German Social Studies Classroom

    Science.gov (United States)

    Ortloff, Debora Hinderliter

    2011-01-01

    Background: In many countries, working towards a truly inclusive national citizenship means deconstructing hegemonic structures that are deeply entrenched. Moving outside of the borders toward a global citizenship hints at giving up on what has been a long road toward multicultural citizenship. A balance between including and empowering diverse…

  10. Using inventory data to determine the impact of drought on tree mortality

    Science.gov (United States)

    Greg C. Liknes; Christopher W. Woodall; Charles H. Perry

    2012-01-01

    Drought has been the subject of numerous recent studies that hint at an acceleration of tree mortality due to climate change. In particular, a recent global survey of tree mortality events implicates drought as the cause of quaking aspen mortality in Minnesota, USA in 2007. In this study, data from the Forest Inventory and Analysis program of the USDA Forest Service...

  11. Learning to Read and the Preschool Years

    Science.gov (United States)

    Wilson, Lorraine

    2012-01-01

    You have young preschool children. You think ahead to when they will begin school, and wonder what you might do to make it easy for your children to learn to read. This article offers some hints for parents and caregivers about learning to read: (1) Reading can begin at birth; (2) When reading aloud to an infant, make the experience a warm, loving…

  12. Case Report HeLs malnourished o admit him to the nutrition unit ...

    African Journals Online (AJOL)

    and vocal resonance on the left side, anterior and posterior, with reduced breath ... hint that she may have been the source of the child's HIV infection, before, during or ... child's HIV status? Has either of them been on anti-retroviral therapy?

  13. Frontier detectors for frontier physics

    International Nuclear Information System (INIS)

    Cervelli, F.; Scribano, A.

    1984-01-01

    These proceedings contain the articles presented at the named meeting. These concern developments of radiation detectors and counting techniques in high energy physics. Especially considered are tracking detectors, calorimeters, time projection chambers, detectors for rare events, solid state detectors, particle identification, and optical readout systems. See hints under the relevant topics. (HSI)

  14. Structure and distribution of cross-links in boron-modified phenol-formaldehyde resins designed for soft magnetic composites: a multiple-quantum 11B-11B MAS NMR correlation spectroscopy study

    Czech Academy of Sciences Publication Activity Database

    Kobera, Libor; Czernek, Jiří; Strečková, M.; Urbanová, Martina; Abbrent, Sabina; Brus, Jiří

    2015-01-01

    Roč. 48, č. 14 (2015), s. 4874-4881 ISSN 0024-9297 R&D Projects: GA MŠk(CZ) LD14010 Grant - others:European Commission(XE) COST Action MP1202 HINT Institutional support: RVO:61389013 Keywords : phenol-formaldehyde polymers * boron crosslinks * soft magnetic composites Subject RIV: CD - Macromolecular Chemistry Impact factor: 5.554, year: 2015

  15. The role of individual differences on the effect of synchronous coaching of trainee teachers in plenary situations

    NARCIS (Netherlands)

    Hooreman, Ralph W.; Kommers, Petrus A.M.; Jochems, Wim M.G.

    2008-01-01

    Historically, synchronous (direct) coaching is an addition to the traditional asynchronous (indirect) supervision of trainee teachers. The new trainee receives concrete hints on “how to proceed further” via an earpiece. In this study the role of personality traits and the orientation of learning to

  16. Quality Assurance for a TLD Based Individual Monitoring Service (invited paper)

    Energy Technology Data Exchange (ETDEWEB)

    Julius, H.W.; Van Dijk, J.W.E. [Arnhem (Netherlands)

    1999-07-01

    Approved Individual Monitoring Services should, in addition to complying with specific national performance requirements, also have implemented a quality assurance (QA) and quality control (QC) programme as an integral part of the operation. Essential elements of a QA/QC programme are discussed. Some practical hints and examples of QA practices are given, focussing on the application of thermoluminescence dosimetry. (author)

  17. Kleit Evelinile / Britt Rosen

    Index Scriptorium Estoniae

    Rosen, Britt, 1968-

    2009-01-01

    Moekunstnikud Aldo Järvsoo, Kirill Safonov, Anu Samarüütel-Long, Anu Hint, Reet Aus, Anne Metsis, Xenia Jedomskihh, Kätlin Kaljuvee ja Mari Aakre joonistasid proua Evelin Ilvesele vabariigi aastapäeva vastuvõtuks õhtukleidi

  18. Pedagogy and Japanese Culture in a Distance Learning Environment

    Science.gov (United States)

    Anderson, Bodi O.

    2012-01-01

    Current theoretical models of distance learning are driven by two impetuses: a technical CMC element, and a pedagogical foundation rooted strongly in the Western world, and driven by social constructivism. By and large these models have been exported throughout the world as-is. However, previous research has hinted at potential problems with these…

  19. The perception of aquaculture on the Swedish West Coast

    DEFF Research Database (Denmark)

    Thomas, Jean-Baptiste E.; Nordström, Leif Jonas; Risén, Emma

    2017-01-01

    neutral responses. On the whole, respondents were favourable to the depicted scenario. Finally, it was found that the high-awareness group tended to be more supportive than the low or medium-awareness groups, hinting at the benefits of increasing awareness to reduce public aversion and to support...... a sustainable development of aquaculture on the Swedish West Coast....

  20. Impact of the layout on the electrical characteristics of double-sided silicon 3D sensors fabricated at FBK

    Energy Technology Data Exchange (ETDEWEB)

    Povoli, M., E-mail: povoli@disi.unitn.it [Dipartimento di Ingegneria e Scienza dell' Informazione, Università di Trento, Via Sommarive, 14, I-38123 Povo di Trento (Italy); INFN, Sezione di Padova (Gruppo Collegato di Trento) (Italy); Bagolini, A.; Boscardin, M. [Fondazione Bruno Kessler, Centro per i Materiali e i Microsistemi (FBK-CMM), Via Sommarive, 18, I-38123 Povo di Trento, TN (Italy); Dalla Betta, G.-F. [Dipartimento di Ingegneria e Scienza dell' Informazione, Università di Trento, Via Sommarive, 14, I-38123 Povo di Trento (Italy); INFN, Sezione di Padova (Gruppo Collegato di Trento) (Italy); Giacomini, G.; Mattedi, F.; Vianello, E.; Zorzi, N. [Fondazione Bruno Kessler, Centro per i Materiali e i Microsistemi (FBK-CMM), Via Sommarive, 18, I-38123 Povo di Trento, TN (Italy)

    2013-01-21

    We report on experimental results and TCAD simulations addressing the impact of layout on the electrical characteristics of double-sided 3D diodes fabricated at Fondazione Bruno Kessler (FBK), Trento, Italy. Simulations are found to accurately reproduce the device characteristics, thus explaining the basic mechanisms governing the breakdown behavior and capacitance of different devices and providing useful hints for layout optimization.

  1. Impact of the layout on the electrical characteristics of double-sided silicon 3D sensors fabricated at FBK

    International Nuclear Information System (INIS)

    Povoli, M.; Bagolini, A.; Boscardin, M.; Dalla Betta, G.-F.; Giacomini, G.; Mattedi, F.; Vianello, E.; Zorzi, N.

    2013-01-01

    We report on experimental results and TCAD simulations addressing the impact of layout on the electrical characteristics of double-sided 3D diodes fabricated at Fondazione Bruno Kessler (FBK), Trento, Italy. Simulations are found to accurately reproduce the device characteristics, thus explaining the basic mechanisms governing the breakdown behavior and capacitance of different devices and providing useful hints for layout optimization.

  2. Single top t-channel

    CERN Document Server

    Faltermann, Nils

    2017-01-01

    The production of single top quarks allows to study the interplay of top quark physics and the electroweak sector of the standard model. Deviations from predictions can be a hint for physics beyond the standard model. The t-channel is the dominant production mode for single top quarks at the LHC. This talk presents the latest measurements from the ATLAS and CMS collaborations.

  3. High grade serous ovarian carcinoma with serous tubal intraepithelial carcinoma in a case presented with atypical glandular cell favor neoplasm cervical cytology and dermatomyositis

    Directory of Open Access Journals (Sweden)

    Mun-Kun Hong

    2015-04-01

    Conclusion: The patient had serous carcinoma of the ovary with tubal STIC, which presented as dermatomyositis. The AGC-FN identified from a Pap smear hinted at a diagnosis of ovarian carcinoma. These presentations point to an occult malignancy in the genital tract and demand careful diagnostic workup.

  4. 11th ECR ion source workshop

    International Nuclear Information System (INIS)

    1993-05-01

    This report contains four articles concerning the commissioning of the 14 GHz ECR at the new Unilac injector, the status of the PuMa-ECR, the redesigned 14 GHz ECR ion source and test bench, and the simulation of ion beam extraction from an ECR source. See hints under the relevant topics. (HSI)

  5. Homophobic Slurs and Public Apologies: The Discursive Struggle over "Fag/Maricon" in Public Discourse

    Science.gov (United States)

    Cashman, Holly R.

    2012-01-01

    A handful of recent incidents hints at an ideological struggle over the use of the English word "fag(got)" and the Spanish word "maricon" in public discourse. This article examines the discursive and ideological struggle over the terms through the comparison of two cases in which Spanish/English bilingual Latinos in the U. S. use what might be…

  6. Johannes Hindi tütar Pille Pae : inimlik headus ei sõltu rezhiimist / Pille Pae ; interv. Anneli Ammas

    Index Scriptorium Estoniae

    Pae, Pille

    2006-01-01

    Desintegraatori juhi Johannes Hindi tütar Pille Pae vastab küsimustele, mis puudutavad tema isa armuandmispalve esitamist, isale toetusallkirjade kogumist ning Arnold Rüütli suhteid Johannes Hindiga. Lisa: Kes oli Johannes Hint ja mis Desintegraator?

  7. Anomalies in Flavour physics

    CERN Document Server

    Chrzaszcz, Marcin Jakub

    2015-01-01

    LHCb is measuring more and more deviations in electroweak penguin measurements, both in the angular observables (like P5') and the branching fractions. Furthermore, there are strong hints of lepton universality breaking in semileptonic decays. This talk aims to present the results of these measurements and the implications for new physics. A result of a global fit will be presented.

  8. Rules of the Game for Women

    Science.gov (United States)

    Canty, Becky

    2005-01-01

    In "Play Like a Man, Win Like a Woman," Gail Evans' matter-of-fact directness contributes so many helpful hints about success that women need to learn. Playing to their strengths and characteristics as women is important to enhance their professional success. In the author's working life as a superintendent (which included three years as a theatre…

  9. Moving and Being Moved: Implications for Practice.

    Science.gov (United States)

    Kretchmar, R. Scott

    2000-01-01

    Uses philosophical writings, a novel about baseball, and a nonfiction work on rowing to analyze levels of meaning in physical activity, showing why three popular methods for enhancing meaning have not succeeded and may have moved some students away from deeper levels of meaning. The paper suggests that using hints taken from the three books could…

  10. Evolution of direct mechanisms with incident energy from the Coulomb-barrier to relativistic energies. - Two-center effects in nucleon transfer between nuclei. - Signatures of nucleon promotion in heavy ion reactions at barrier energies

    International Nuclear Information System (INIS)

    Oertzen, W. von; Voit, H.; Imanishi, B.

    1988-10-01

    This report contains a review article considering the evolution of direct mechanisms with incident energy in heavy ion reactions and two theoretical articles concerning two-center effects in transfer reactions between heavy ions and the nucleon promotion in heavy ion reactions. See hints under the relevant topics. (HSI)

  11. The Peroxisome Proliferator-Activated Receptor α is dispensable for cold-induced adipose tissue browning in mice

    NARCIS (Netherlands)

    Defour, Merel; Dijk, Wieneke; Ruppert, Philip; Nascimento, Emmani B.M.; Schrauwen, Patrick; Kersten, Sander

    2018-01-01

    Objective: Chronic cold exposure causes white adipose tissue (WAT) to adopt features of brown adipose tissue (BAT), a process known as browning. Previous studies have hinted at a possible role for the transcription factor Peroxisome Proliferator-Activated Receptor alpha (PPARα) in cold-induced

  12. Proceedings of the workshop on crystalline ion beams

    International Nuclear Information System (INIS)

    Hasse, R.W.; Hofmann, I.; Liesen, D.

    1989-04-01

    The workshop consisted of mainly invited and some contributed papers. More informal discussions took place in three working groups on the following topics: beam cooling techniques; diagnostics of crystalline beams; storage rings for crystalline beams. The present volume collects all papers as well as the summaries of the working groups. See hints under the relevant topics. (orig./HSI)

  13. Ask-Elle: An Adaptable Programming Tutor for Haskell Giving Automated Feedback

    Science.gov (United States)

    Gerdes, Alex; Heeren, Bastiaan; Jeuring, Johan; van Binsbergen, L. Thomas

    2017-01-01

    Ask-Elle is a tutor for learning the higher-order, strongly-typed functional programming language Haskell. It supports the stepwise development of Haskell programs by verifying the correctness of incomplete programs, and by providing hints. Programming exercises are added to Ask-Elle by providing a task description for the exercise, one or more…

  14. Gamification for low-literates: findings on motivation, user experience, and study design

    NARCIS (Netherlands)

    Schouten, D.G.M.; Pfab, I.; Cremers, A.H.M.; Dijk, B. van; Neerincx, M.A.

    2014-01-01

    This study investigated the effects of the gamification elements of scaffolding, score and hints on the user enjoyment and motivation of people of low literacy. In a four-condition within-subjects experiment, participants per-formed mental spatial ability tests with the aforementioned elements.

  15. Elementary functional analysis

    CERN Document Server

    Shilov, Georgi E

    1996-01-01

    Introductory text covers basic structures of mathematical analysis (linear spaces, metric spaces, normed linear spaces, etc.), differential equations, orthogonal expansions, Fourier transforms - including problems in the complex domain, especially involving the Laplace transform - and more. Each chapter includes a set of problems, with hints and answers. Bibliography. 1974 edition.

  16. e+e- collisions at 500 GeV: The physics potential

    International Nuclear Information System (INIS)

    Zerwas, P.M.

    1992-08-01

    This report is the second part of the proceedings, which contain the articles presented at the named workshop. The articles in these proceedings concern extended gauge models; supersymmetry; alternative particle models; as well as beamstrahlung and photon-photon interactions. See hints under the relevant topics. (HSI)

  17. Approximating methods for intractable probabilistic models: Applications in neuroscience

    DEFF Research Database (Denmark)

    Højen-Sørensen, Pedro

    2002-01-01

    This thesis investigates various methods for carrying out approximate inference in intractable probabilistic models. By capturing the relationships between random variables, the framework of graphical models hints at which sets of random variables pose a problem to the inferential step. The appro...

  18. Wireless communications surpassing fiber capacity : micro- and millimeter-wave solutions up to D-band for 5G systems

    NARCIS (Netherlands)

    Olmos, J. J.Vegas; Monroy, I. Tafur

    2017-01-01

    In this paper, we present the latest experimental work on millimetre-wave links operating at fiber-like capacity regimes: from UWB communications supporting up to 35 Gbit/s to D-band communications operating at 352 Gbit/s. We provide insights on these technologies and hints on next steps to achieve

  19. Neutrino μ - τ reflection symmetry and its breaking in the minimal seesaw

    OpenAIRE

    Liu, Zhi-Cheng; Yue, Chong-Xing; Zhao, Zhen-Hua

    2017-01-01

    In this paper, we attempt to implement the neutrino $\\mu$-$\\tau$ reflection symmetry (which predicts $\\theta^{}_{23} = \\pi/4$ and $\\delta = \\pm \\pi/2$ as well as trivial Majorana phases) in the minimal seesaw (which enables us to fix the neutrino masses). For some direct (the preliminary experimental hints towards $\\theta^{}_{23} \

  20. Whale Watching in the Gulf of Maine.

    Science.gov (United States)

    Carkin, Clayton A.

    1985-01-01

    Describes a variety of teaching strategies to prepare a class for a whale watching field trip. Guidelines for recording a sighting, pictures and statistics for commonly and/or occasionally seen whales, and hints for avoiding sea sickness are included. (DH)