Sample records for highly efficient pna

  1. Efficient in vitro inhibition of HIV-1 gag reverse transcription by peptide nucleic acid (PNA) at minimal ratios of PNA/RNA

    DEFF Research Database (Denmark)

    Koppelhus, Uffe; Zachar, Vladimir; Nielsen, P.E.


    of reverse transcription was obtained at approximately 6-fold molar excess of the bis-PNA with respect to the gag RNA. At this molar ratio we found no effect on in vitro translation of gag RNA. A 15mer duplex-forming PNA was also found to inhibit reverse transcription at very low molar ratios of PNA/ gag RNA...... that would indicate PNA-mediated RNase H activation of the tested RTs. In conclusion, PNA appears to have a potential to become a specific and efficient inhibitor of reverse transcription in vivo , provided sufficient intracellular levels are achievable....

  2. Efficient in vitro inhibition of HIV-1 gag reverse transcription by peptide nucleic acid (PNA) at minimal ratios of PNA/RNA

    DEFF Research Database (Denmark)

    Koppelhus, Uffe; Zachar, Vladimir; Nielsen, P.E.


    We have tested the inhibitory potential of peptide nucleic acid (PNA) on in vitro reverse transcription of the HIV-1 gag gene. PNA was designed to target different regions of the HIV-1 gag gene and the effect on reverse transcription by HIV-1, MMLV and AMV reverse transcriptases (RTs...... that would indicate PNA-mediated RNase H activation of the tested RTs. In conclusion, PNA appears to have a potential to become a specific and efficient inhibitor of reverse transcription in vivo , provided sufficient intracellular levels are achievable.......) was investigated. We found that a bis-PNA (parallel antisense 10mer linked to antiparallel antisense 10mer) was superior to both the parallel antisense 10mer and antiparallel antisense 10mer in inhibiting reverse transcription of the gene, thus indicating triplex formation at the target sequence. A complete arrest...

  3. A novel method to highly versatile monomeric PNA building blocks by multi component reactions

    NARCIS (Netherlands)

    Dömling, Alexander; Chi, Kai-Zu; Barrère, Mathieux


    A novel approach to monomeric PNA building blocks by a solution phase Ugi multi component reaction (MCR) is described. The reaction is easily performed in 96 well plates. The products precipitate from the reaction solution and are thus obtained in high yields and purity. Those products are not

  4. Efficient in vitro inhibition of HIV-1 gag reverse transcription by peptide nucleic acid (PNA) at minimal ratios of PNA/RNA

    DEFF Research Database (Denmark)

    Koppelhus, Uffe; Zachar, Vladimir; Nielsen, P.E.


    ) was investigated. We found that a bis-PNA (parallel antisense 10mer linked to antiparallel antisense 10mer) was superior to both the parallel antisense 10mer and antiparallel antisense 10mer in inhibiting reverse transcription of the gene, thus indicating triplex formation at the target sequence. A complete arrest......We have tested the inhibitory potential of peptide nucleic acid (PNA) on in vitro reverse transcription of the HIV-1 gag gene. PNA was designed to target different regions of the HIV-1 gag gene and the effect on reverse transcription by HIV-1, MMLV and AMV reverse transcriptases (RTs...... of reverse transcription was obtained at approximately 6-fold molar excess of the bis-PNA with respect to the gag RNA. At this molar ratio we found no effect on in vitro translation of gag RNA. A 15mer duplex-forming PNA was also found to inhibit reverse transcription at very low molar ratios of PNA/ gag RNA...

  5. PNA Peptide chimerae

    DEFF Research Database (Denmark)

    Koch, T.; Næsby, M.; Wittung, P.


    Radioactive labelling of PNA has been performed try linking a peptide segment to the PNA which is substrate for protein kinase A. The enzymatic phosphorylation proceeds in almost quantitative yields.......Radioactive labelling of PNA has been performed try linking a peptide segment to the PNA which is substrate for protein kinase A. The enzymatic phosphorylation proceeds in almost quantitative yields....

  6. PNA-based fluorescence in situ hybridization for identification of bacteria in clinical samples

    DEFF Research Database (Denmark)

    Fazli, Mustafa; Bjarnsholt, Thomas; Høiby, Niels


    Fluorescence in situ hybridization with PNA probes (PNA-FISH) that target specific bacterial ribosomal RNA sequences is a powerful and rapid tool for identification of bacteria in clinical samples. PNA can diffuse readily through the bacterial cell wall due to its uncharged backbone, and PNA-FISH...... can be performed with high specificity due to the extraordinary thermal stability of RNA-PNA hybrid complexes. We describe a PNA-FISH procedure and provide examples of the application of PNA-FISH for the identification of bacteria in chronic wounds, cystic fibrosis lungs, and soft tissue fillers...

  7. Antibacterial Peptide Nucleic Acid-Antimicrobial Peptide (PNA-AMP) Conjugates

    DEFF Research Database (Denmark)

    Hansen, Anna Mette; Bonke, Gitte; Larsen, Camilla Josephine


    Antisense peptide nucleic acid (PNA) oligomers constitute a novel class of potential antibiotics that inhibit bacterial growth via specific knockdown of essential gene expression. However, discovery of efficient, nontoxic delivery vehicles for such PNA oligomers has remained a challenge...

  8. Enhanced splicing correction effect by an oligo-aspartic acid-PNA conjugate and cationic carrier complexes. (United States)

    Bae, Yun Mi; Kim, Myung Hee; Yu, Gwang Sig; Um, Bong Ho; Park, Hee Kyung; Lee, Hyun-il; Lee, Kang Taek; Suh, Yung Doug; Choi, Joon Sig


    Peptide nucleic acids (PNAs) are synthetic structural analogues of DNA and RNA. They recognize specific cellular nucleic acid sequences and form stable complexes with complementary DNA or RNA. Here, we designed an oligo-aspartic acid-PNA conjugate and showed its enhanced delivery into cells with high gene correction efficiency using conventional cationic carriers, such as polyethylenimine (PEI) and Lipofectamine 2000. The negatively charged oligo-aspartic acid-PNA (Asp(n)-PNA) formed complexes with PEI and Lipofectamine, and the resulting Asp(n)-PNA/PEI and Asp(n)-PNA/Lipofectamine complexes were introduced into cells. We observed significantly enhanced cellular uptake of Asp(n)-PNA by cationic carriers and detected an active splicing correction effect even at nanomolar concentrations. We found that the splicing correction efficiency of the complex depended on the kind of the cationic carriers and on the number of repeating aspartic acid units. By enhancing the cellular uptake efficiency of PNAs, these results may provide a novel platform technology of PNAs as bioactive substances for their biological and therapeutic applications. Copyright © 2013 Elsevier B.V. All rights reserved.

  9. A Tat-conjugated Peptide Nucleic Acid Tat-PNA-DR Inhibits Hepatitis B Virus Replication In Vitro and In Vivo by Targeting LTR Direct Repeats of HBV RNA (United States)

    Zeng, Zhengyang; Han, Shisong; Hong, Wei; Lang, Yange; Li, Fangfang; Liu, Yongxiang; Li, Zeyong; Wu, Yingliang; Li, Wenxin; Zhang, Xianzheng; Cao, Zhijian


    Hepatitis B virus (HBV) infection is a major cause of chronic active hepatitis, cirrhosis, and primary hepatocellular carcinoma, all of which are severe threats to human health. However, current clinical therapies for HBV are limited by potential side effects, toxicity, and drug-resistance. In this study, a cell-penetrating peptide-conjugated peptide nucleic acid (PNA), Tat-PNA-DR, was designed to target the direct repeat (DR) sequences of HBV. Tat-PNA-DR effectively inhibited HBV replication in HepG2.2.15 cells. Its anti-HBV effect relied on the binding of Tat-PNA-DR to the DR, whereby it suppressed the translation of hepatitis B e antigen (HBeAg), HBsAg, HBV core, hepatitis B virus x protein, and HBV reverse transcriptase (RT) and the reverse transcription of the HBV genome. Furthermore, Tat-PNA-DR administered by intravenous injection efficiently cleared HBeAg and HBsAg in an acute hepatitis B mouse model. Importantly, it induced an 80% decline in HBV DNA in mouse serum, which was similar to the effect of the widely used clinical drug Lamivudine (3TC). Additionally, a long-term hydrodynamics HBV mouse model also demonstrated Tat-PNA-DR's antiviral effect. Interestingly, Tat-PNA-DR displayed low cytotoxicity, low mouse acute toxicity, low immunogenicity, and high serum stability. These data indicate that Tat-PNA-DR is a unique PNA and a promising drug candidate against HBV. PMID:26978579

  10. Peptide nucleic acid (PNA) antisense effects in Escherichia coli

    DEFF Research Database (Denmark)

    Good, L; Nielsen, P E


    Antisense peptide nucleic acid (PNA) can be used to control cell growth, gene expression and growth phenotypes in the bacteria Escherichia coli. PNAs targeted to the RNA components of the ribosome can inhibit translation and cell growth, and PNAs targeted to mRNA can limit gene expression with gene...... and sequence specificity. In an E. coli cell extract, efficient inhibition is observed when using PNA concentrations in the nanomolar range, whereas micromolar concentrations are required for inhibition in growing cells. A mutant strain of E. coli that is more permeable to antibiotics also is more susceptible...... to antisense PNAs than the wild type. This chapter details methods for testing the antisense activities of PNA in E. coli. As an example of the specific antisense inhibition possible, we show the effects of an anti-beta-galactosidase PNA in comparison to control PNAs. With improvements in cell uptake...

  11. Ultrasensitive FRET-based DNA sensor using PNA/DNA hybridization. (United States)

    Yang, Lan-Hee; Ahn, Dong June; Koo, Eunhae


    In the diagnosis of genetic diseases, rapid and highly sensitive DNA detection is crucial. Therefore, many strategies for detecting target DNA have been developed, including electrical, optical, and mechanical methods. Herein, a highly sensitive FRET based sensor was developed by using PNA (Peptide Nucleic Acid) probe and QD, in which red color QDs are hybridized with capture probes, reporter probes and target DNAs by EDC-NHS coupling. The hybridized probe with target DNA gives off fluorescent signal due to the energy transfer from QD to Cy5 dye in the reporter probe. Compared to the conventional DNA sensor using DNA probes, the DNA sensor using PNA probes shows higher FRET factor and efficiency due to the higher reactivity between PNA and target DNA. In addition, to elicit the effect of the distance between the donor and the acceptor, we have investigated two types of the reporter probes having Cy5 dyes attached at the different positions of the reporter probes. Results show that the shorter the distance between QDs and Cy5s, the stronger the signal intensity. Furthermore, based on the fluorescence microscopy images using microcapillary chips, the FRET signal is enhanced to be up to 276% times stronger than the signal obtained using the cuvette by the fluorescence spectrometer. These results suggest that the PNA probe system conjugated with QDs can be used as ultrasensitive DNA nanosensors. Copyright © 2016. Published by Elsevier B.V.

  12. Sub-attomolar electrochemical measurement of DNA hybridization based on the detection of high coverage biobarcode latex labels at PNA-modified screen printed electrodes. (United States)

    Widaningrum, Tarina; Widyastuti, Endrika; Pratiwi, Feby Wijaya; Faidoh Fatimah, Ai Imas; Rijiravanich, Patsamon; Somasundrum, Mithran; Surareungchai, Werasak


    We have constructed biobarcode labels based on 468nm diameter latex spheres. Modification with polyallylamine and then glutaraldehyde was used to attach a high DNA loading, consisting of aminated probe DNA (approx. 1.01×102 molecules per sphere) and biobarcode DNA (approx. 1.66×104 molecules per sphere). Detection of the biobarcodes was performed by application of a Ag enhancer solution, causing association of the Ag+ ions with the phosphate groups of the DNA. The deposited Ag was detected by differential pulse voltammetry. A 30 mer sequence from the BL21 strain of E. coli was detected with an LOD of 2.6fM (calibration range 10 aM to 0.1pM, r2=0.91, n=45). The LOD was lowered to 0.56aM (calibration range 100zM to 0.1nM, r2=0.991, n=50) by utilizing a sandwich assay with PNA-modified screen printed electrodes, which lowered the Ag background current. The sandwich assay platform was used to calibrate E. coli strain BL2(DE3) with an LOD of 17.0 CFU mL-1 (calibration range 10 to 106 CFU mL-1, r2=0.99, n=33) with good discrimination against Salmonella. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Applications of PNA-Based Artificial Restriction DNA Cutters. (United States)

    Shigi, Narumi; Sumaoka, Jun; Komiyama, Makoto


    More than ten years ago, artificial restriction DNA cutters were developed by combining two pseudo-complementary peptide nucleic acid (pcPNA) strands with either Ce(IV)/EDTA or S1 nuclease. They have remarkably high site-specificity and can cut only one predetermined site in the human genome. In this article, recent progress of these man-made tools have been reviewed. By cutting the human genome site-selectively, desired fragments can be clipped from either the termini of chromosomes (telomeres) or from the middle of genome. These fragments should provide important information on the biological functions of complicated genome system. DNA/RNA hybrid duplexes, which are formed in living cells, are also site-selectively hydrolyzed by these cutters. In order to further facilitate the applications of the artificial DNA cutters, various chemical modifications have been attempted. One of the most important successes is preparation of PNA derivatives which can form double-duplex invasion complex even under high salt conditions. This is important for in vivo applications, since the inside of living cells is abundant of metal ions. Furthermore, site-selective DNA cutters which require only one PNA strand, in place of a pair of pcPNA strands, are developed. This progress has opened a way to new fields of PNA-based biochemistry and biotechnology.

  14. Nanomolar Cellular Antisense Activity of Peptide Nucleic Acid (PNA) Cholic Acid ("Umbrella") and Cholesterol Conjugates Delivered by Cationic Lipids

    DEFF Research Database (Denmark)

    Shiraishi, Takehiko; Nielsen, Peter E


    of cholesterol and cholic acid ("umbrella") derivatives of splice correction antisense PNA oligomers. While the conjugates alone were practically inactive up to 1 µM, their activity was dramatically improved when delivered by a cationic lipid transfection agent (LipofectAMINE2000). In particular, PNAs...... volume improved transfection efficiency, suggesting that accumulation (condensation) of the PNA/lipid complex on the cellular surface is part of the uptake mechanism. These results provide a novel, simple method for very efficient cellular delivery of PNA oligomers, especially using PNA-cholic acid...

  15. Probing of miniPEGγ-PNA-DNA Hybrid Duplex Stability with AFM Force Spectroscopy. (United States)

    Dutta, Samrat; Armitage, Bruce A; Lyubchenko, Yuri L


    Peptide nucleic acids (PNA) are synthetic polymers, the neutral peptide backbone of which provides elevated stability to PNA-PNA and PNA-DNA hybrid duplexes. It was demonstrated that incorporation of diethylene glycol (miniPEG) at the γ position of the peptide backbone increased the thermal stability of the hybrid duplexes (Sahu, B. et al. J. Org. Chem. 2011, 76, 5614-5627). Here, we applied atomic force microscopy (AFM) based single molecule force spectroscopy and dynamic force spectroscopy (DFS) to test the strength and stability of the hybrid 10 bp duplex. This hybrid duplex consisted of miniPEGγ-PNA and DNA of the same length (γ(MP)PNA-DNA), which we compared to a DNA duplex with a homologous sequence. AFM force spectroscopy data obtained at the same conditions showed that the γ(MP)PNA-DNA hybrid is more stable than the DNA counterpart, 65 ± 15 pN vs 47 ± 15 pN, respectively. The DFS measurements performed in a range of pulling speeds analyzed in the framework of the Bell-Evans approach yielded a dissociation constant, koff ≈ 0.030 ± 0.01 s⁻¹ for γ(MP)PNA-DNA hybrid duplex vs 0.375 ± 0.18 s⁻¹ for the DNA-DNA duplex suggesting that the hybrid duplex is much more stable. Correlating the high affinity of γ(MP)PNA-DNA to slow dissociation kinetics is consistent with prior bulk characterization by surface plasmon resonance. Given the growing interest in γ(MP)PNA as well as other synthetic DNA analogues, the use of single molecule experiments along with computational analysis of force spectroscopy data will provide direct characterization of various modifications as well as higher order structures such as triplexes and quadruplexes.

  16. Inhibition of multidrug resistance by SV40 pseudovirion delivery of an antigene peptide nucleic acid (PNA in cultured cells.

    Directory of Open Access Journals (Sweden)

    Benjamin Macadangdang

    Full Text Available Peptide nucleic acid (PNA is known to bind with extraordinarily high affinity and sequence-specificity to complementary nucleic acid sequences and can be used to suppress gene expression. However, effective delivery into cells is a major obstacle to the development of PNA for gene therapy applications. Here, we present a novel method for the in vitro delivery of antigene PNA to cells. By using a nucleocapsid protein derived from Simian virus 40, we have been able to package PNA into pseudovirions, facilitating the delivery of the packaged PNA into cells. We demonstrate that this system can be used effectively to suppress gene expression associated with multidrug resistance in cancer cells, as shown by RT-PCR, flow cytometry, Western blotting, and cell viability under chemotherapy. The combination of PNA with the SV40-based delivery system is a method for suppressing a gene of interest that could be broadly applied to numerous targets.

  17. Structural Studies on Porphyrin-PNA Conjugates in Parallel PNA:PNA Duplexes: Effect of Stacking Interactions on Helicity. (United States)

    Accetta, Alessandro; Petrovic, Ana G; Marchelli, Rosangela; Berova, Nina; Corradini, Roberto


    Parallel PNA:PNA duplexes were synthesized and conjugated with meso-tris(pyridyl)phenylporphyrin carboxylic acid at the N-terminus. The introduction of one porphyrin unit was shown to affect slightly the stability of the PNA:PNA parallel duplex, whereas the presence of two porphyrin units at the same end resulted in a dramatic increase of the melting temperature, accompanied by hysteresis between melting and cooling curves. The circular dichroism (CD) profile of the Soret band and fluorescence quenching strongly support the occurrence of a face-to-face interaction between the two porphyrin units. Introduction of a L-lysine residue at the C-terminal of one strand of the parallel duplex induced a left-handed helical structure in the PNA:PNA duplex if the latter contains only one or no porphyrin moiety. The left-handed helicity was revealed by nucleobase CD profile at 240-280 nm and by the induced-CD observed in the presence of the DiSC2 (5) cyanine dye at ~500-550 nm. Surprisingly, the presence of two porphyrin units led to the disappearance of the nucleobase CD signal and the absence of CD exciton coupling within the Soret band region. In addition, a dramatic decrease of induced CD of DiSC2 (5) was observed. These results are in agreement with a model where the porphyrin-porphyrin interactions cause partial loss of chirality of the PNA:PNA parallel duplex, forcing it to adopt a ladder-like conformation. © 2015 Wiley Periodicals, Inc.

  18. Sequence-specific inhibition of duck hepatitis B virus reverse transcription by peptide nucleic acids (PNA)

    DEFF Research Database (Denmark)

    Robaczewska, Magdalena; Narayan, Ramamurthy; Seigneres, Beatrice


    BACKGROUND/AIMS: Peptide nucleic acids (PNAs) appear as promising new antisense agents, that have not yet been examined as hepatitis B virus (HBV) inhibitors. Our aim was to study the ability of PNAs targeting the duck HBV (DHBV) encapsidation signal epsilon to inhibit reverse transcription (RT...... inhibitor than the PNA targeting only the bulge. Importantly, the inhibition was highly sequence-specific since double-mismatched PNA had no effect on the RT reaction. Moreover, in PDH the PNA coupled to Arg(7) cationic delivery peptide decreased DHBV replication. CONCLUSIONS: We provide the first evidence...

  19. High efficiency incandescent lighting (United States)

    Bermel, Peter; Ilic, Ognjen; Chan, Walker R.; Musabeyoglu, Ahmet; Cukierman, Aviv Ruben; Harradon, Michael Robert; Celanovic, Ivan; Soljacic, Marin


    Incandescent lighting structure. The structure includes a thermal emitter that can, but does not have to, include a first photonic crystal on its surface to tailor thermal emission coupled to, in a high-view-factor geometry, a second photonic filter selected to reflect infrared radiation back to the emitter while passing visible light. This structure is highly efficient as compared to standard incandescent light bulbs.

  20. Telomere Q-PNA-FISH--reliable results from stochastic signals.

    Directory of Open Access Journals (Sweden)

    Andrea Cukusic Kalajzic

    Full Text Available Structural and functional analysis of telomeres is very important for understanding basic biological functions such as genome stability, cell growth control, senescence and aging. Recently, serious concerns have been raised regarding the reliability of current telomere measurement methods such as Southern blot and quantitative polymerase chain reaction. Since telomere length is associated with age related pathologies, including cardiovascular disease and cancer, both at the individual and population level, accurate interpretation of measured results is a necessity. The telomere Q-PNA-FISH technique has been widely used in these studies as well as in commercial analysis for the general population. A hallmark of telomere Q-PNA-FISH is the wide variation among telomere signals which has a major impact on obtained results. In the present study we introduce a specific mathematical and statistical analysis of sister telomere signals during cell culture senescence which enabled us to identify high regularity in their variations. This phenomenon explains the reproducibility of results observed in numerous telomere studies when the Q-PNA-FISH technique is used. In addition, we discuss the molecular mechanisms which probably underlie the observed telomere behavior.

  1. Highly efficient high temperature electrolysis

    DEFF Research Database (Denmark)

    Hauch, Anne; Ebbesen, Sune; Jensen, Søren Højgaard


    High temperature electrolysis of water and steam may provide an efficient, cost effective and environmentally friendly production of H-2 Using electricity produced from sustainable, non-fossil energy sources. To achieve cost competitive electrolysis cells that are both high performing i.e. minimum...... electrolysis is favourable from a thermodynamic point of view, because a part of the required energy can be supplied as thermal heat, and the activation barrier is lowered increasing the H-2 production rate. Only two types of cells operating at high temperature (above 200 degrees C) have been described...... electrolysis using SOECs is competitive to H-2 production from fossil fuels at electricity prices below 0.02-0.03 is an element of per kWh. Though promising SOEC results on H-2 production have been reported a substantial R&D is still required to obtain inexpensive, high performing and long-term stable...

  2. Yeasts identification in microfluidic devices using peptide nucleic acid fluorescence in situ hybridization (PNA-FISH). (United States)

    Ferreira, André M; Cruz-Moreira, Daniela; Cerqueira, Laura; Miranda, João M; Azevedo, Nuno F


    Peptide nucleic acid fluorescence in situ hybridization (PNA-FISH) is a highly specific molecular method widely used for microbial identification. Nonetheless, and due to the detection limit of this technique, a time-consuming pre-enrichment step is typically required before identification. In here we have developed a lab-on-a-chip device to concentrate cell suspensions and speed up the identification process in yeasts. The PNA-FISH protocol was optimized to target Saccharomyces cerevisiae, a common yeast that is very relevant for several types of food industries. Then, several coin-sized microfluidic devices with different geometries were developed. Using Computational fluid dynamics (CFD), we modeled the hydrodynamics inside the microchannels and selected the most promising options. SU-8 structures were fabricated based on the selected designs and used to produce polydimethylsiloxane-based microchips by soft lithography. As a result, an integrated approach combining microfluidics and PNA-FISH for the rapid identification of S. cerevisiae was achieved. To improve fluid flow inside microchannels and the PNA-FISH labeling, oxygen plasma treatment was applied to the microfluidic devices and a new methodology to introduce the cell suspension and solutions into the microchannels was devised. A strong PNA-FISH signal was observed in cells trapped inside the microchannels, proving that the proposed methodology works as intended. The microfluidic designs and PNA-FISH procedure described in here should be easily adaptable for detection of other microorganisms of similar size.





    Varma designed ultra modern and high efficiency turbines which can use gas, steam or fuels as feed to produce electricity or mechanical work for wide range of usages and applications in industries or at work sites. Varma turbine engines can be used in all types of vehicles. These turbines can also be used in aircraft, ships, battle tanks, dredgers, mining equipment, earth moving machines etc, Salient features of Varma Turbines. 1. Varma turbines are simple in design, easy to manufac...

  4. Modulating gene function with peptide nucleic acids (PNA)

    DEFF Research Database (Denmark)

    Nielsen, Peter E.; Crooke, Stanley T.


    A review on peptide nucleic acid (PNA) oligomers as modulators of gene expression ranging from gene silencing at the mRNAor the dsDNA (antigene) level, and redirection of mRNA splicing to gene activation through transcription bubble mimicking. PNA chem., anti-infective agents, cellular delivery, ......, and in vivo bioavailability of PNA are briefly discussed. [on SciFinder (R)]...

  5. Focus on PNA Flexibility and RNA Binding using Molecular Dynamics and Metadynamics (United States)

    Verona, Massimiliano Donato; Verdolino, Vincenzo; Palazzesi, Ferruccio; Corradini, Roberto


    Peptide Nucleic Acids (PNAs) can efficiently target DNA or RNA acting as chemical tools for gene regulation. Their backbone modification and functionalization is often used to increase the affinity for a particular sequence improving selectivity. The understanding of the trading forces that lead the single strand PNA to bind the DNA or RNA sequence is preparatory for any further rational design, but a clear and unique description of this process is still not complete. In this paper we report further insights into this subject, by a computational investigation aiming at the characterization of the conformations of a single strand PNA and how these can be correlated to its capability in binding DNA/RNA. Employing Metadynamics we were able to better define conformational pre-organizations of the single strand PNA and γ-modified PNA otherwise unrevealed through classical molecular dynamics. Our simulations driven on backbone modified PNAs lead to the conclusion that this γ-functionalization affects the single strand preorganization and targeting properties to the DNA/RNA, in agreement with circular dichroism (CD) spectra obtained for this class of compounds. MD simulations on PNA:RNA dissociation and association mechanisms allowed to reveal the critical role of central bases and preorganization in the binding process.

  6. High-efficiency CARM

    Energy Technology Data Exchange (ETDEWEB)

    Bratman, V.L.; Kol`chugin, B.D.; Samsonov, S.V.; Volkov, A.B. [Institute of Applied Physics, Nizhny Novgorod (Russian Federation)


    The Cyclotron Autoresonance Maser (CARM) is a well-known variety of FEMs. Unlike the ubitron in which electrons move in a periodical undulator field, in the CARM the particles move along helical trajectories in a uniform magnetic field. Since it is much simpler to generate strong homogeneous magnetic fields than periodical ones for a relatively low electron energy ({Brit_pounds}{le}1-3 MeV) the period of particles` trajectories in the CARM can be sufficiently smaller than in the undulator in which, moreover, the field decreases rapidly in the transverse direction. In spite of this evident advantage, the number of papers on CARM is an order less than on ubitron, which is apparently caused by the low (not more than 10 %) CARM efficiency in experiments. At the same time, ubitrons operating in two rather complicated regimes-trapping and adiabatic deceleration of particles and combined undulator and reversed guiding fields - yielded efficiencies of 34 % and 27 %, respectively. The aim of this work is to demonstrate that high efficiency can be reached even for a simplest version of the CARM. In order to reduce sensitivity to an axial velocity spread of particles, a short interaction length where electrons underwent only 4-5 cyclotron oscillations was used in this work. Like experiments, a narrow anode outlet of a field-emission electron gun cut out the {open_quotes}most rectilinear{close_quotes} near-axis part of the electron beam. Additionally, magnetic field of a small correcting coil compensated spurious electron oscillations pumped by the anode aperture. A kicker in the form of a sloping to the axis frame with current provided a control value of rotary velocity at a small additional velocity spread. A simple cavity consisting of a cylindrical waveguide section restricted by a cut-off waveguide on the cathode side and by a Bragg reflector on the collector side was used as the CARM-oscillator microwave system.

  7. A New FRET-Based Sensitive DNA Sensor for Medical Diagnostics using PNA Probe and Water-Soluble Blue Light Emitting Polymer

    Directory of Open Access Journals (Sweden)

    Nidhi Mathur


    Full Text Available A reliable, fast, and low-cost biosensor for medical diagnostics using DNA sequence detection has been developed and tested for the detection of the bacterium “Bacillus anthracis.” In this sensor, Poly [9,9-di (6,6′- N, N′ trimethylammonium hexylfluorenyl-2, 7-diyl-alt-co- (1,4-phenylene] dibromide salt (PFP has been taken as cationic conjugated polymer (CCP and PNA attached with fluorescein dye (PNAC∗ as a probe. The basic principle of this sensor is that when a PNAC∗ probe is hybridized with a single strand DNA (ssDNA having complementary sequence, Forster resonance energy transfer (FRET may take place from PFP to the PNAC∗/DNA complex. If the FRET is efficient, the photoluminescence from the PFP will be highly quenched and that from PNAC∗ will be enhanced. On the other hand, if the DNA sequence is noncomplementary to PNA, FRET will not occur.

  8. High efficiency poplar transformation. (United States)

    Cseke, Leland J; Cseke, Sarah Beth; Podila, Gopi K


    With the completion of the poplar tree genome database, Populus species have become one of the most useful model systems for the study of woody plant biology. Populus tremuloides (quaking aspen) is the most wide-spread tree species in North America, and its rapid growth generates the most abundant wood-based biomass out of any other plant species. To study such beneficial traits, there is a need for easier and more efficient transformation procedures that will allow the study of large numbers of tree genes. We have developed transformation procedures that are suitable for high-throughput format transformations using either Agrobacterium tumefaciens to produce transformed trees or Agrobacterium rhizogenes to generate hairy roots. Our method uses Agrobacterium inoculated aspen seedling hypocotyls followed by direct thidiazuron (TDZ)-mediated shoot regeneration on selective media. Transformation was verified through beta-glucuronidase (GUS) reporter gene expression in all tree tissues, PCR amplification of appropriate vector products from isolated genomic DNA, and northern hybridization of incorporated and expressed transgenes. The hairy root protocol follows the same inoculation procedures and was tested using GUS reporter gene integration and antibiotic selection. The benefit of these procedures is that they are simple and efficient, requiring no maintenance of starting materials and allowing fully formed transgenic trees (or hairy roots) to be generated in only 3-4 months, rather than the 6-12 months required by more traditional methods. Likewise, the fact that the protocols are amenable to high-throughput formats makes them better suited for large-scale functional genomics studies in poplars.

  9. A practical approach to FRET-based PNA fluorescence in situ hybridization. (United States)

    Blanco, Ana M; Artero, Rubén


    Given the demand for improved methods for detecting and characterizing RNA variants in situ, we developed a quantitative method for detecting RNA alternative splicing variants that combines in situ hybridization of fluorescently labeled peptide nucleic acid (PNA) probes with confocal microscopy Förster resonance energy transfer (FRET). The use of PNA probes complementary to sequences flanking a given splice junction allows to specifically quantify, within the cell, the RNA isoform generating such splice junction as FRET efficiency measure. The FRET-based PNA fluorescence in situ hybridization (FP-FISH) method offers a conceptually new approach for characterizing at the subcellular level not only splice variant isoform structure, location, and dynamics but also potentially a wide variety of close range RNA-RNA interactions. In this paper, we explain the FP-FISH technique workflow for reliable and reproducible results. Copyright © 2010 Elsevier Inc. All rights reserved.

  10. High Efficiency Integrated Package

    Energy Technology Data Exchange (ETDEWEB)

    Ibbetson, James


    Solid-state lighting based on LEDs has emerged as a superior alternative to inefficient conventional lighting, particularly incandescent. LED lighting can lead to 80 percent energy savings; can last 50,000 hours – 2-50 times longer than most bulbs; and contains no toxic lead or mercury. However, to enable mass adoption, particularly at the consumer level, the cost of LED luminaires must be reduced by an order of magnitude while achieving superior efficiency, light quality and lifetime. To become viable, energy-efficient replacement solutions must deliver system efficacies of ≥ 100 lumens per watt (LPW) with excellent color rendering (CRI > 85) at a cost that enables payback cycles of two years or less for commercial applications. This development will enable significant site energy savings as it targets commercial and retail lighting applications that are most sensitive to the lifetime operating costs with their extended operating hours per day. If costs are reduced substantially, dramatic energy savings can be realized by replacing incandescent lighting in the residential market as well. In light of these challenges, Cree proposed to develop a multi-chip integrated LED package with an output of > 1000 lumens of warm white light operating at an efficacy of at least 128 LPW with a CRI > 85. This product will serve as the light engine for replacement lamps and luminaires. At the end of the proposed program, this integrated package was to be used in a proof-of-concept lamp prototype to demonstrate the component’s viability in a common form factor. During this project Cree SBTC developed an efficient, compact warm-white LED package with an integrated remote color down-converter. Via a combination of intensive optical, electrical, and thermal optimization, a package design was obtained that met nearly all project goals. This package emitted 1295 lm under instant-on, room-temperature testing conditions, with an efficacy of 128.4 lm/W at a color temperature of ~2873

  11. Controlled assembly of SNAP-PNA-fluorophore systems on DNA templates to produce fluorescence resonance energy transfer. (United States)

    Gholami, Zahra; Hanley, Quentin


    The SNAP protein is a widely used self-labeling tag that can be used for tracking protein localization and trafficking in living systems. A model system providing controlled alignment of SNAP-tag units can provide a new way to study clustering of fusion proteins. In this work, fluorescent SNAP-PNA conjugates were controllably assembled on DNA frameworks, forming dimers, trimers, and tetramers. Modification of peptide nucleic acid (PNA) with the O(6)-benzyl guanine (BG) group allowed the generation of site-selective covalent links between PNA and the SNAP protein. The modified BG-PNAs were labeled with fluorescent Atto dyes and subsequently chemo-selectively conjugated to SNAP protein. Efficient assembly into dimer and oligomer forms was verified via size exclusion chromatography (SEC), electrophoresis (SDS-PAGE), and fluorescence spectroscopy. DNA-directed assembly of homo- and heterodimers of SNAP-PNA constructs induced homo- and hetero-FRET, respectively. Longer DNA scaffolds controllably aligned similar fluorescent SNAP-PNA constructs into higher oligomers exhibiting homo-FRET. The combined SEC and homo-FRET studies indicated the 1:1 and saturated assemblies of SNAP-PNA-fluorophore:DNA formed preferentially in this system. This suggested a kinetic/stoichiometric model of assembly rather than binomially distributed products. These BG-PNA-fluorophore building blocks allow facile introduction of fluorophores and/or assembly directing moieties onto any protein containing SNAP. Template-directed assembly of PNA-modified SNAP proteins may be used to investigate clustering behavior both with and without fluorescent labels, which may find use in the study of assembly processes in cells.

  12. Selective recognition of DNA from olive leaves and olive oil by PNA and modified-PNA microarrays (United States)

    Rossi, Stefano; Calabretta, Alessandro; Tedeschi, Tullia; Sforza, Stefano; Arcioni, Sergio; Baldoni, Luciana; Corradini, Roberto; Marchelli, Rosangela


    PNA probes for the specific detection of DNA from olive oil samples by microarray technology were developed. The presence of as low as 5% refined hazelnut (Corylus avellana) oil in extra-virgin olive oil (Olea europaea L.) could be detected by using a PNA microarray. A set of two single nucleotide polymorphisms (SNPs) from the Actin gene of Olive was chosen as a model for evaluating the ability of PNA probes for discriminating olive cultivars. Both unmodified and C2-modified PNAs bearing an arginine side-chain were used, the latter showing higher sequence specificity. DNA extracted from leaves of three different cultivars (Ogliarola leccese, Canino and Frantoio) could be easily discriminated using a microarray with unmodified PNA probes, whereas discrimination of DNA from oil samples was more challenging, and could be obtained only by using chiral PNA probes. PMID:22772038

  13. Advanced high efficiency concentrator cells

    Energy Technology Data Exchange (ETDEWEB)

    Gale, R. (Varian Associates, Inc., Palo Alto, CA (United States). Varian Research Center)


    This report describes research to develop the technology needed to demonstrate a monolithic, multijunction, two-terminal, concentrator solar cell with a terrestrial power conversion efficiency greater than 35%. Under three previous subcontracts, Varian developed many of the aspects of a technology needed to fabricate very high efficiency concentrator cells. The current project was aimed at exploiting the new understanding of high efficiency solar cells. Key results covered in this report are as follows. (1) A 1.93-eV AlGaAs/1.42-eV GaAs metal-interconnected cascade cell was manufactured with a one-sun efficiency at 27.6% at air mass 1.5 (AM1.5) global. (2) A 1.0eV InGaAs cell was fabricated on the reverse'' side of a low-doped GaAs substrate with a one-sun efficiency of 2.5% AM1.5 diffuse and a short-circuit current of 14.4 mA/cm{sup 2}. (3) Small-scale manufacturing of GaAs p/n concentrator cells was attempted and obtained an excellent yield of high-efficiency cells. (4) Grown-in tunnel junction cell interconnects that are transparent and thermally stable using C and Si dopants were developed. 10 refs.

  14. Expanding the scope of PNA-encoded synthesis (PES): Mtt-protected PNA fully orthogonal to fmoc chemistry and a broad array of robust diversity-generating reactions. (United States)

    Chouikhi, Dalila; Ciobanu, Mihai; Zambaldo, Claudio; Duplan, Vincent; Barluenga, Sofia; Winssinger, Nicolas


    Nucleic acid-encoded libraries are emerging as an attractive and highly miniaturized format for the rapid identification of protein ligands. An important criterion in the synthesis of nucleic acid encoded libraries is the scope of reactions that can be used to introduce molecular diversity and devise divergent pathways for diversity-oriented synthesis (DOS). To date, the protecting group strategies that have been used in peptide nucleic acid (PNA) encoded synthesis (PES) have limited the choice of reactions used in the library synthesis to just a few prototypes. Herein, we describe the preparation of PNA monomers with a protecting group combination (Mtt/Boc) that is orthogonal to Fmoc-based synthesis and compatible with a large palette of reactions that have been productively used in DOS (palladium cross-couplings, metathesis, reductive amination, amidation, heterocycle formation, nucleophilic addition, conjugate additions, Pictet-Spengler cyclization). We incorporate γ-modifications in the PNA backbone that are known to enhance hybridization and solubility. We demonstrate the robustness of this strategy with a library synthesis that is characterized by MALDI MS analysis at every step. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  15. Clinical consequences of using PNA-FISH in Staphylococcal bacteraemia

    DEFF Research Database (Denmark)

    Laub, R R; Knudsen, Inge Jenny Dahl


    To optimize patient treatment and rational use of antimicrobials, it is important to provide fast information on findings in blood-cultures (BCs). The purpose of this study was to evaluate the impact of using peptide nucleic acid fluorescence in situ hybridization (PNA-FISH) on positive BCs......NS in the year 2011 were identified and the charts were reviewed retrospectively. The group of patients with BCs tested with PNA-FISH was compared to the group of patients with untested BCs. A total of 200 patients with SA and 725 patients with CoNS were included. The mean number of contacts was 0.82 when PNA-FISH...... showed CoNS and 1.39 when PNA-FISH was not done (p ...

  16. Thermodynamics of sequence-specific binding of PNA to DNA

    DEFF Research Database (Denmark)

    Ratilainen, T; Holmén, A; Tuite, E


    For further characterization of the hybridization properties of peptide nucleic acids (PNAs), the thermodynamics of hybridization of mixed sequence PNA-DNA duplexes have been studied. We have characterized the binding of PNA to DNA in terms of binding affinity (perfectly matched duplexes) and seq......For further characterization of the hybridization properties of peptide nucleic acids (PNAs), the thermodynamics of hybridization of mixed sequence PNA-DNA duplexes have been studied. We have characterized the binding of PNA to DNA in terms of binding affinity (perfectly matched duplexes...... relative to that of the perfectly matched sequence with a corresponding free energy penalty of about 15 kJ mol(-1) bp(-1). The average cost of a single mismatch is therefore estimated to be on the order of or larger than the gain of two matched base pairs, resulting in an apparent binding constant of only...

  17. Unconventional, High-Efficiency Propulsors

    DEFF Research Database (Denmark)

    Andersen, Poul


    The development of ship propellers has generally been characterized by search for propellers with as high efficiency as possible and at the same time low noise and vibration levels and little or no cavitation. This search has lead to unconventional propulsors, like vane-wheel propulsors, contra-r...

  18. High Efficiency Room Air Conditioner

    Energy Technology Data Exchange (ETDEWEB)

    Bansal, Pradeep [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)


    This project was undertaken as a CRADA project between UT-Battelle and Geberal Electric Company and was funded by Department of Energy to design and develop of a high efficiency room air conditioner. A number of novel elements were investigated to improve the energy efficiency of a state-of-the-art WAC with base capacity of 10,000 BTU/h. One of the major modifications was made by downgrading its capacity from 10,000 BTU/hr to 8,000 BTU/hr by replacing the original compressor with a lower capacity (8,000 BTU/hr) but high efficiency compressor having an EER of 9.7 as compared with 9.3 of the original compressor. However, all heat exchangers from the original unit were retained to provide higher EER. The other subsequent major modifications included- (i) the AC fan motor was replaced by a brushless high efficiency ECM motor along with its fan housing, (ii) the capillary tube was replaced with a needle valve to better control the refrigerant flow and refrigerant set points, and (iii) the unit was tested with a drop-in environmentally friendly binary mixture of R32 (90% molar concentration)/R125 (10% molar concentration). The WAC was tested in the environmental chambers at ORNL as per the design rating conditions of AHAM/ASHRAE (Outdoor- 95F and 40%RH, Indoor- 80F, 51.5%RH). All these modifications resulted in enhancing the EER of the WAC by up to 25%.

  19. High Efficiency Germanium Immersion Gratings

    Energy Technology Data Exchange (ETDEWEB)

    Kuzmenko, P J; Davis, P J; Little, S L; Little, L M; Bixler, J V


    We have fabricated several germanium immersion gratings by single crystal, single point diamond flycutting on an ultra-precision lathe. Use of a dead sharp tool produces groove corners less than 0.1 micron in radius and consequently high diffraction efficiency. We measured first order efficiencies in immersion of over 80% at 10.6 micron wavelength. Wavefront error was low averaging 0.06 wave rms (at 633 nm) across the full aperture. The grating spectral response was free of ghosts down to our detection limit of 1 part in 10{sup 4}. Scatter should be low based upon the surface roughness. Measurement of the spectral line profile of a CO{sub 2} laser sets an upper bound on total integrated scatter of 0.5%.

  20. En busca de visibilidad internacional: el caso de PNA


    Molina, Marta; Cañadas, María C.; Gallardo, Jesús; Gómez, Pedro; Lupiáñez, José Luis


    En este trabajo se describe el diseño y desarrollo del proyecto que ha dado lugar a PNA, la única revista española especializada en investigación en Educación Matemática. Es una revista de acceso abierto, que publica estudios de investigación, experimentales o teóricos. Dichos trabajos han sido revisados por pares de forma anónima, están escritos en inglés o en español y siguen las normas de estilo APA. PNA es editada, en formato electrónico ( e impreso, por el grupo de investigaci...

  1. PNA Directed Sequence Addressed Self-Assembly of DNA Nanostructures

    DEFF Research Database (Denmark)

    Nielsen, Peter E.


    sequence specifically recognize another PNA oligomer. We describe how such three domain PNAs have utility for assembling dsDNA grid and clover leaf structures, and in combination with SNAP-tag technol. of protein dsDNA structures. (c) 2008 American Institute of Physics. [on SciFinder (R)] Udgivelsesdato...

  2. Gene Targeting and Expression Modulation by Peptide Nucleic Acids (PNA)

    DEFF Research Database (Denmark)

    Nielsen, Peter E


    Peptide nucleic acids (PNA) are artificial structural mimics of nucleic acids capable of sequence specific hybridization to both RNA and DNA. Thus they have obvious potential as gene targeting agents for drug discovery approaches. An overview with emphasis on recent progress on RNA "interference"...

  3. High efficiency, long life terrestrial solar panel (United States)

    Chao, T.; Khemthong, S.; Ling, R.; Olah, S.


    The design of a high efficiency, long life terrestrial module was completed. It utilized 256 rectangular, high efficiency solar cells to achieve high packing density and electrical output. Tooling for the fabrication of solar cells was in house and evaluation of the cell performance was begun. Based on the power output analysis, the goal of a 13% efficiency module was achievable.


    Directory of Open Access Journals (Sweden)

    A. K. Esman


    Full Text Available Recent research and development show promising use of high-performance solid-state receivers of the electromagnetic radiation. These receivers are based on the low-barrier Schottky diodes. The approach to the design of the receivers on the basis of delta-doped low-barrier Schottky diodes with beam leads without bias is especially actively developing because for uncooled receivers of the microwave radiation these diodes have virtually no competition. The purpose of this work is to improve the main parameters and characteristics that determine the practical relevance of the receivers of mid-infrared electromagnetic radiation at the operating room temperature by modifying the electrodes configuration of the diode and optimizing the distance between them. Proposed original design solution of the integrated receiver of mid-infrared radiation on the basis of the low-barrier Schottky diodes with beam leads allows to effectively adjust its main parameters and characteristics. Simulation of the electromagnetic characteristics of the proposed receiver by using the software package HFSS with the basic algorithm of a finite element method which implemented to calculate the behavior of electromagnetic fields on an arbitrary geometry with a predetermined material properties have shown that when the inner parts of the electrodes of the low-barrier Schottky diode is performed in the concentric elliptical convex-concave shape, it can be reduce the reflection losses to -57.75 dB and the standing wave ratio to 1.003 while increasing the directivity up to 23 at a wavelength of 6.09 μm. At this time, the rounded radii of the inner parts of the anode and cathode electrodes are equal 212 nm and 318 nm respectively and the gap setting between them is 106 nm. These parameters will improve the efficiency of the developed infrared optical-promising and electronic equipment for various purposes intended for work in the mid-infrared wavelength range. 

  5. High-efficiency wind turbine (United States)

    Hein, L. A.; Myers, W. N.


    Vertical axis wind turbine incorporates several unique features to extract more energy from wind increasing efficiency 20% over conventional propeller driven units. System also features devices that utilize solar energy or chimney effluents during periods of no wind.

  6. High Efficiency Refrigeration Process Project (United States)

    National Aeronautics and Space Administration — It has been proposed by NASA JSC studies, that the most mass efficient (non-nuclear) method of Lunar habitat cooling is via photovoltaic (PV) direct vapor...

  7. High efficiency turbine blade coatings

    Energy Technology Data Exchange (ETDEWEB)

    Youchison, Dennis L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Gallis, Michail A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)


    The development of advanced thermal barrier coatings (TBCs) of yttria stabilized zirconia (YSZ) that exhibit lower thermal conductivity through better control of electron beam - physical vapor deposition (EB-PVD) processing is of prime interest to both the aerospace and power industries. This report summarizes the work performed under a two-year Lab-Directed Research and Development (LDRD) project (38664) to produce lower thermal conductivity, graded-layer thermal barrier coatings for turbine blades in an effort to increase the efficiency of high temperature gas turbines. This project was sponsored by the Nuclear Fuel Cycle Investment Area. Therefore, particular importance was given to the processing of the large blades required for industrial gas turbines proposed for use in the Brayton cycle of nuclear plants powered by high temperature gas-cooled reactors (HTGRs). During this modest (~1 full-time equivalent (FTE)) project, the processing technology was developed to create graded TBCs by coupling ion beam-assisted deposition (IBAD) with substrate pivoting in the alumina-YSZ system. The Electron Beam - 1200 kW (EB-1200) PVD system was used to deposit a variety of TBC coatings with micron layered microstructures and reduced thermal conductivity below 1.5 W/m.K. The use of IBAD produced fully stoichiometric coatings at a reduced substrate temperature of 600°C and a reduced oxygen background pressure of 0.1 Pa. IBAD was also used to successfully demonstrate the transitioning of amorphous PVD-deposited alumina to the -phase alumina required as an oxygen diffusion barrier and for good adhesion to the substrate Ni2Al3 bondcoat. This process replaces the time consuming thermally grown oxide formation required before the YSZ deposition. In addition to the process technology, Direct Simulation Monte Carlo plume modeling and spectroscopic characterization of the PVD plumes were performed. The project consisted of five tasks. These included the

  8. Towards high efficiency heliostat fields (United States)

    Arbes, Florian; Wöhrbach, Markus; Gebreiter, Daniel; Weinrebe, Gerhard


    CSP power plants have great potential to substantially contribute to world energy supply. To set this free, cost reductions are required for future projects. Heliostat field layout optimization offers a great opportunity to improve field efficiency. Field efficiency primarily depends on the positions of the heliostats around the tower, commonly known as the heliostat field layout. Heliostat shape also influences efficiency. Improvements to optical efficiency results in electricity cost reduction without adding any extra technical complexity. Due to computational challenges heliostat fields are often arranged in patterns. The mathematical models of the radial staggered or spiral patterns are based on two parameters and thus lead to uniform patterns. Optical efficiencies of a heliostat field do not change uniformly with the distance to the tower, they even differ in the northern and southern field. A fixed pattern is not optimal in many parts of the heliostat field, especially when used as large scaled heliostat field. In this paper, two methods are described which allow to modify field density suitable to inconsistent field efficiencies. A new software for large scale heliostat field evaluation is presented, it allows for fast optimizations of several parameters for pattern modification routines. It was used to design a heliostat field with 23,000 heliostats, which is currently planned for a site in South Africa.

  9. High efficiency stationary hydrogen storage

    Energy Technology Data Exchange (ETDEWEB)

    Hynek, S.; Fuller, W.; Truslow, S. [Arthur D. Little, Inc., Cambridge, MA (United States)


    Stationary storage of hydrogen permits one to make hydrogen now and use it later. With stationary hydrogen storage, one can use excess electrical generation capacity to power an electrolyzer, and store the resultant hydrogen for later use or transshipment. One can also use stationary hydrogen as a buffer at fueling stations to accommodate non-steady fueling demand, thus permitting the hydrogen supply system (e.g., methane reformer or electrolyzer) to be sized to meet the average, rather than the peak, demand. We at ADL designed, built, and tested a stationary hydrogen storage device that thermally couples a high-temperature metal hydride to a phase change material (PCM). The PCM captures and stores the heat of the hydriding reaction as its own heat of fusion (that is, it melts), and subsequently returns that heat of fusion (by freezing) to facilitate the dehydriding reaction. A key component of this stationary hydrogen storage device is the metal hydride itself. We used nickel-coated magnesium powder (NCMP) - magnesium particles coated with a thin layer of nickel by means of chemical vapor deposition (CVD). Magnesium hydride can store a higher weight fraction of hydrogen than any other practical metal hydride, and it is less expensive than any other metal hydride. We designed and constructed an experimental NCM/PCM reactor out of 310 stainless steel in the form of a shell-and-tube heat exchanger, with the tube side packed with NCMP and the shell side filled with a eutectic mixture of NaCL, KCl, and MgCl{sub 2}. Our experimental results indicate that with proper attention to limiting thermal losses, our overall efficiency will exceed 90% (DOE goal: >75%) and our overall system cost will be only 33% (DOE goal: <50%) of the value of the delivered hydrogen. It appears that NCMP can be used to purify hydrogen streams and store hydrogen at the same time. These prospects make the NCMP/PCM reactor an attractive component in a reformer-based hydrogen fueling station.

  10. A high efficiency microturbine concept


    Malkamäki, Matti; Jaatinen-Värri, Ahti; Honkatukia, Ahti; Backman, Jari; Larjola, Jaakko


    There is a growing trend towards decentralized electricity and heat production throughout the world. Reciprocating engines and gas turbines have an essential role in the global decentralized energy markets and any improvement in their electrical efficiency has a significant impact from the environmental and economic viewpoints. This paper introduces an inter-cooled and recuperated two-shaft microturbine at 500 kW electric output range. The microturbine is optimized for a realistic combination...

  11. Sequence specific inhibition of DNA restriction enzyme cleavage by PNA

    DEFF Research Database (Denmark)

    Nielsen, P.E.; Egholm, M.; Berg, R.H.


    Plasmids containing double-stranded 10-mer PNA (peptide nucleic acid chimera) targets proximally flanked by two restriction enzyme sites were challenged with the complementary PNA or PNAs having one or two mismatches, and the effect on the restriction enzyme cleavage of the flanking sites...... was assayed. The following PNAs were used: T10-LysNH2, T5CT4-LysNH2 and T2CT2CT4-LysNH2 and the corresponding targets cloned into pUC 19 were flanked by BamH1, Sal1 or Pstl sites, respectively. In all cases it was found that complete inhibition of restriction enzyme cleavage was obtained...

  12. Highly Efficient Freestyle Magnetic Nanoswimmer. (United States)

    Li, Tianlong; Li, Jinxing; Morozov, Konstantin I; Wu, Zhiguang; Xu, Tailin; Rozen, Isaac; Leshansky, Alexander M; Li, Longqiu; Wang, Joseph


    The unique swimming strategies of natural microorganisms have inspired recent development of magnetic micro/nanorobots powered by artificial helical or flexible flagella. However, as artificial nanoswimmers with unique geometries are being developed, it is critical to explore new potential modes for kinetic optimization. For example, the freestyle stroke is the most efficient of the competitive swimming strokes for humans. Here we report a new type of magnetic nanorobot, a symmetric multilinked two-arm nanoswimmer, capable of efficient "freestyle" swimming at low Reynolds numbers. Excellent agreement between the experimental observations and theoretical predictions indicates that the powerful "freestyle" propulsion of the two-arm nanorobot is attributed to synchronized oscillatory deformations of the nanorobot under the combined action of magnetic field and viscous forces. It is demonstrated for the first time that the nonplanar propulsion gait due to the cooperative "freestyle" stroke of the two magnetic arms can be powered by a plane oscillatory magnetic field. These two-arm nanorobots are capable of a powerful propulsion up to 12 body lengths per second, along with on-demand speed regulation and remote navigation. Furthermore, the nonplanar propulsion gait powered by the consecutive swinging of the achiral magnetic arms is more efficient than that of common chiral nanohelical swimmers. This new swimming mechanism and its attractive performance opens new possibilities in designing remotely actuated nanorobots for biomedical operation at the nanoscale.

  13. High-efficiency solar concentrator (United States)

    Lansing, F. L.; Dorman, J.


    A new type of solar concentrator is presented using liquid lenses and simple translational tracking mechanism. The concentrator achieves a 100:1 nominal concentration ratio and is compared in performance with a flat-plate collector having two sheets of glazing and non-selective coating. The results of the thermal analysis show that higher temperatures can be obtained with the concentrator than is possible with the non-concentrator flat-plate type. Furthermore, the thermal efficiency far exceeds that of the comparative flat-plate type for all operating conditions.

  14. High efficiency focus neutron generator (United States)

    Sadeghi, H.; Amrollahi, R.; Zare, M.; Fazelpour, S.


    In the present paper, the new idea to increase the neutron yield of plasma focus devices is investigated and the results are presented. Based on many studies, more than 90% of neutrons in plasma focus devices were produced by beam target interactions and only 10% of them were due to thermonuclear reactions. While propounding the new idea, the number of collisions between deuteron ions and deuterium gas atoms were increased remarkably well. The COMSOL Multiphysics 5.2 was used to study the given idea in the known 28 plasma focus devices. In this circumstance, the neutron yield of this system was also obtained and reported. Finally, it was found that in the ENEA device with 1 Hz working frequency, 1.1 × 109 and 1.1 × 1011 neutrons per second were produced by D–D and D–T reactions, respectively. In addition, in the NX2 device with 16 Hz working frequency, 1.34 × 1010 and 1.34 × 1012 neutrons per second were produced by D–D and D–T reactions, respectively. The results show that with regards to the sizes and energy of these devices, they can be used as the efficient neutron generators.

  15. Label-free DNA electrochemical sensor based on a PNA-functionalized conductive polymer

    DEFF Research Database (Denmark)

    Reisberg, S; Dang, L A; Nguyen, Q A


    An electrochemical hybridization biosensor based on peptide nucleic acid (PNA) probe is presented. PNA were attached covalently onto a quinone-based electroactive polymer. Changes in flexibility of the PNA probe strand upon hybridization generates electrochemical changes at the polymer-solution i......An electrochemical hybridization biosensor based on peptide nucleic acid (PNA) probe is presented. PNA were attached covalently onto a quinone-based electroactive polymer. Changes in flexibility of the PNA probe strand upon hybridization generates electrochemical changes at the polymer......-solution interface. A reagentless and direct electrochemical detection was obtained by detection of the electrochemical changes using square wave voltammetry (SWV). An increase in the peak current of quinone was observed upon hybridization of probe on the target, whereas no change is observed with non...

  16. High-Efficiency Power Module (United States)

    Simons, Rainee N. (Inventor); Wintucky, Edwin G. (Inventor)


    One or more embodiments of the present invention pertain to an all solid-state microwave power module. The module includes a plurality of solid-state amplifiers configured to amplify a signal using a low power stage, a medium power stage, and a high power stage. The module also includes a power conditioner configured to activate a voltage sequencer (e.g., bias controller) when power is received from a power source. The voltage sequencer is configured to sequentially apply voltage to a gate of each amplifier and sequentially apply voltage to a drain of each amplifier.

  17. Sensitive detection of nucleic acids by PNA hybridization directed co-localization of fluorescent beads

    DEFF Research Database (Denmark)

    Shiraishi, Takehiko; Deborggraeve, Stijn; Büscher, Philippe


    We have designed a pair of biotinylated peptide nucleic acid (PNA) probes targeting two sequences in 18S rRNA (from the parasite Trypanosoma brucei) at a distance of 191 nt (corresponding to maximum distance of ca. 60 nm) from each other. The PNA probes were individually bound to (strept)avidin-c......We have designed a pair of biotinylated peptide nucleic acid (PNA) probes targeting two sequences in 18S rRNA (from the parasite Trypanosoma brucei) at a distance of 191 nt (corresponding to maximum distance of ca. 60 nm) from each other. The PNA probes were individually bound to (strept...

  18. PNA FISH: an intelligent stain for rapid diagnosis of infectious diseases. (United States)

    Stender, Henrik


    Fluorescence in situ hybridization using peptide nucleic acid probes (PNA FISH) is a novel diagnostic technique combining the simplicity of traditional staining procedures with the unique performance of PNA probes to provide rapid and accurate diagnosis of infectious diseases; a feature that makes PNA FISH well suited for routine application and enables clinical microbiology laboratories to report important information for patient therapy within a time frame not possible using classic biochemical methods. Having transitioned from an academic curiosity into an advanced diagnostic tool, PNA probes are now debuting on the infectious disease stage, representing the new generation of therapy-directing diagnostics.

  19. Highly-efficient high-power pumps for fiber lasers (United States)

    Gapontsev, V.; Moshegov, N.; Berezin, I.; Komissarov, A.; Trubenko, P.; Miftakhutdinov, D.; Berishev, I.; Chuyanov, V.; Raisky, O.; Ovtchinnikov, A.


    We report on high efficiency multimode pumps that enable ultra-high efficiency high power ECO Fiber Lasers. We discuss chip and packaged pump design and performance. Peak out-of-fiber power efficiency of ECO Fiber Laser pumps was reported to be as high as 68% and was achieved with passive cooling. For applications that do not require Fiber Lasers with ultimate power efficiency, we have developed passively cooled pumps with out-of-fiber power efficiency greater than 50%, maintained at operating current up to 22A. We report on approaches to diode chip and packaged pump design that possess such performance.

  20. Single base pair mutation analysis by PNA directed PCR clamping

    DEFF Research Database (Denmark)

    Ørum, H.; Nielsen, P.E.; Egholm, M.


    A novel method that allows direct analysis of single base mutation by the polymerase chain reaction (PCR) is described. The method utilizes the finding that PNAs (peptide nucleic acids) recognize and bind to their complementary nucleic acid sequences with higher thermal stability and specificity...... allows selective amplification/suppression of target sequences that differ by only one base pair. Finally we show that PNAs can be designed in such a way that blockage can be accomplished when the PNA target sequence is located between the PCR primers....

  1. High Efficiency Low Scatter Echelle Grating Project (United States)

    National Aeronautics and Space Administration — A high efficiency low scatter echelle grating will be developed using a novel technique of multiple diamond shaving cuts. The grating will have mirror surfaces on...

  2. High Efficiency Solar Furnace Core Project (United States)

    National Aeronautics and Space Administration — It is proposed to develop a high efficiency solar furnace core that greatly lessens the heat losses from the furnace core, either greatly reducing the amount of...

  3. High-efficiency crystalline silicon technology development (United States)

    Prince, M. B.


    The rationale for pursuing high efficiency crystalline silicon technology research is discussed. Photovoltaic energy systems are reviewed as to their cost effectiveness and their competitiveness with other energy systems. The parameters of energy system life are listed and briefly reviewed.

  4. Large bandwidth, highly efficient optical gratings through high index materials

    NARCIS (Netherlands)

    Rathgen, H.; Offerhaus, Herman L.


    We analyze the diffraction characteristics of dielectric gratings that feature a high index grating layer, and devise, through rigorous numeri-cal calculations, large bandwidth, highly efficient, high dispersion dielectric gratings in reflection, transmission, and immersed transmission geometry. A

  5. Achieve efficient nitrogen removal from real sewage in a plug-flow integrated fixed-film activated sludge (IFAS) reactor via partial nitritation/anammox pathway. (United States)

    Yang, Yandong; Zhang, Liang; Cheng, Jun; Zhang, Shujun; Li, Baikun; Peng, Yongzhen


    This study tested the feasibility of plug-flow integrated fixed-film activated sludge (IFAS) reactor in applying sewage partial nitritation/anammox (PN/A) process. The IFAS reactor was fed with real pre-treated sewage (C/N ratio=1.3) and operated for 200days. High nitrogen removal efficiency of 82% was achieved with nitrogen removal rates of 0.097±0.019kgN/(m(3)·d). Therefore, plug-flow IFAS reactor could be an alternative to applying sewage PN/A process. Besides, it was found that the stability of sewage PN/A process was significantly affected by residual ammonium. Nitrate accumulated in effluent and PN/A performance deteriorated when residual ammonium was below 1mg/L. On the contrary, long-term stable PN/A operation was achieved when residual ammonium was over 3mg/L. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Promoting selective fisheries through certification? An analysis of the PNA unassociated-sets purse seine fishery

    NARCIS (Netherlands)

    Groeneveld, R.A.; Quaas, Martin F.


    The certification by the Marine Stewardship Council of the unassociated-sets purse seine fishery of the Parties to the Nauru Agreement (PNA) has the potential to improve stocks of the fishery's main three tuna species, as well as to allow the PNA to extract more resource rents from the fishery.

  7. Cellular Antisense Activity of PNA-Oligo(bicycloguanidinium) Conjugates forming Self-Assembled Nano-aggregates

    DEFF Research Database (Denmark)

    Valero, Julian; Shiraishi, Takehiko; de Mendoza, Javier


    A series of peptide nucleic acid-oligo(bicycloguanidinium) (PNA-BGn) conjugates have been synthesized and characterized in terms of cellular antisense activity using the pLuc750HeLa cell splice correction assay. PNA-BG4 conjugates exhibit low micromolar antisense activity and the cellular activit...

  8. Electroporation Enhanced Effect of Dystrophin Splice Switching PNA Oligomers in Normal and Dystrophic Muscle

    DEFF Research Database (Denmark)

    Hjortkjær, Camilla Brolin; Shiraishi, Takehiko; Hojman, Pernille


    Peptide nucleic acid (PNA) is a synthetic DNA mimic that has shown potential for discovery of novel splice switching antisense drugs. However, in vivo cellular delivery has been a limiting factor for development, and only few successful studies have been reported. As a possible modality for impro......Peptide nucleic acid (PNA) is a synthetic DNA mimic that has shown potential for discovery of novel splice switching antisense drugs. However, in vivo cellular delivery has been a limiting factor for development, and only few successful studies have been reported. As a possible modality...... and dystrophic mdx mice with or without electroporation. At low, single PNA doses (1.5, 3, or 10 µg/TA), electroporation augmented the antisense exon skipping induced by an unmodified PNA by twofold to fourfold in healthy mouse muscle with optimized electric parameters, measured after 7 days. The PNA splice...

  9. Synthesis and characterization of metastable, 20 nm-sized Pna2{sub 1}-LiCoPO{sub 4} nanospheres

    Energy Technology Data Exchange (ETDEWEB)

    Ludwig, Jennifer [Technical University of Munich, Department of Chemistry, Synthesis and Characterization of Innovative Materials, Lichtenbergstr. 4, 85747 Garching (Germany); Nordlund, Dennis [Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, 2575 Sand Hill Rd, Menlo Park, CA 94025 (United States); Doeff, Marca M. [Lawrence Berkeley National Laboratory, Environmental Energy Technologies Division, 1 Cyclotron Rd, Berkeley, CA 94720 (United States); Nilges, Tom, E-mail: [Technical University of Munich, Department of Chemistry, Synthesis and Characterization of Innovative Materials, Lichtenbergstr. 4, 85747 Garching (Germany)


    The majority of research activities on LiCoPO{sub 4} are focused on the phospho-olivine (space group Pnma), which is a promising high-voltage cathode material for Li-ion batteries. In contrast, comparably little is known about its metastable Pna2{sub 1} modification. Herein, we present a comprehensive study on the structure–property relationships of 15–20 nm Pna2{sub 1}-LiCoPO{sub 4} nanospheres prepared by a simple microwave-assisted solvothermal process. Unlike previous reports, the results indicate that the compound is non-stoichiometric and shows cation-mixing with Co ions on the Li sites, which provides an explanation for the poor electrochemical performance. Co L{sub 2,3}-edge X-ray absorption spectroscopic data confirm the local tetrahedral symmetry of Co{sup 2+}. Comprehensive studies on the thermal stability using thermogravimetric analysis, differential scanning calorimetry, and in situ powder X-ray diffraction show an exothermic phase transition to olivine Pnma-LiCoPO{sub 4} at 527 °C. The influence of the atmosphere and the particle size on the thermal stability is also investigated. - Graphical abstract: Blue nano-sized Pna2{sub 1}-LiCoPO{sub 4,} featuring tetrahedrally-coordinated Co{sup 2+}, was synthesized in a rapid one-step microwave-assisted solvothermal process. The phase relation between this metastable and the stable polymorph was analyzed and electrochemical properties are discussed. - Highlights: • Preparation of uniform 15–20 nm nanospheres of metastable Pna2{sub 1}-LiCoPO{sub 4} polymorph. • Structure redetermination shows cation-mixing (Co blocking Li sites). • In situ investigation of phase transformation to olivine Pnma-LiCoPO{sub 4} at 527 °C. • Pna2{sub 1}-LiCoPO{sub 4} reemerges as a stable high-temperature phase above 800 °C. • X-ray absorption spectroscopy confirms local tetrahedral symmetry (T{sub d} Co{sup 2+}).

  10. High Efficiency Power Converter for Low Voltage High Power Applications

    DEFF Research Database (Denmark)

    Nymand, Morten

    . A detailed analysis of dominant loss factors in high power converters for low voltage applications is presented. The analysis concludes that: • Power transformers for low voltage high power, if properly designed, will have extremely low leakage inductance. • If optimally designed, boost converters......The topic of this thesis is the design of high efficiency power electronic dc-to-dc converters for high-power, low-input-voltage to high-output-voltage applications. These converters are increasingly required for emerging sustainable energy systems such as fuel cell, battery or photo voltaic based......, if a converter is properly designed, primary side voltage clamp circuits will not even work in low voltage high power converters. • Very high conversion efficiency can be achieved. Peak efficiency of 98% and worst case minimum efficiency of 96.8% are demonstrated on a 1.5 kW converter. The ability...

  11. Highly efficient electrocaloric cooling with electrostatic actuation (United States)

    Ma, Rujun; Zhang, Ziyang; Tong, Kwing; Huber, David; Kornbluh, Roy; Ju, Yongho Sungtaek; Pei, Qibing


    Solid-state refrigeration offers potential advantages over traditional cooling systems, but few devices offer high specific cooling power with a high coefficient of performance (COP) and the ability to be applied directly to surfaces. We developed a cooling device with a high intrinsic thermodynamic efficiency using a flexible electrocaloric (EC) polymer film and an electrostatic actuation mechanism. Reversible electrostatic forces reduce parasitic power consumption and allow efficient heat transfer through good thermal contacts with the heat source or heat sink. The EC device produced a specific cooling power of 2.8 watts per gram and a COP of 13. The new cooling device is more efficient and compact than existing surface-conformable solid-state cooling technologies, opening a path to using the technology for a variety of practical applications.

  12. Technology Development for High Efficiency Optical Communications (United States)

    Farr, William H.


    Deep space optical communications is a significantly more challenging operational domain than near Earth space optical communications, primarily due to effects resulting from the vastly increased range between transmitter and receiver. The NASA Game Changing Development Program Deep Space Optical Communications Project is developing four key technologies for the implementation of a high efficiency telecommunications system that will enable greater than 10X the data rate of a state-of-the-art deep space RF system (Ka-band) for similar transceiver mass and power burden on the spacecraft. These technologies are a low mass spacecraft disturbance isolation assembly, a flight qualified photon counting detector array, a high efficiency flight laser amplifier and a high efficiency photon counting detector array for the ground-based receiver.

  13. A combination of immunohistochemistry and molecular approaches improves highly sensitive detection of BRAF mutations in papillary thyroid cancer. (United States)

    Martinuzzi, Claudia; Pastorino, Lorenza; Andreotti, Virginia; Garuti, Anna; Minuto, Michele; Fiocca, Roberto; Bianchi-Scarrà, Giovanna; Ghiorzo, Paola; Grillo, Federica; Mastracci, Luca


    The optimal method for BRAF mutation detection remains to be determined despite advances in molecular detection techniques. The aim of this study was to compare, against classical Sanger sequencing, the diagnostic performance of two of the most recently developed, highly sensitive methods: BRAF V600E immunohistochemistry (IHC) and peptide nucleic-acid (PNA)-clamp qPCR. BRAF exon 15 mutations were searched in formalin-fixed paraffin-embedded tissues from 86 papillary thyroid carcinoma using the three methods. The limits of detection of Sanger sequencing in borderline or discordant cases were quantified by next generation sequencing. BRAF mutations were found in 74.4 % of cases by PNA, in 71 % of cases by IHC, and in 64 % of cases by Sanger sequencing. Complete concordance for the three methods was observed in 80 % of samples. Better concordance was observed with the combination of two methods, particularly PNA and IHC (59/64) (92 %), while the combination of PNA and Sanger was concordant in 55 cases (86 %). Sensitivity of the three methods was 99 % for PNA, 94.2 % for IHC, and 89.5 % for Sanger. Our data show that IHC could be used as a cost-effective, first-line method for BRAF V600E detection in daily practice, followed by PNA analysis in negative or uninterpretable cases, as the most efficient method. PNA-clamp quantitative PCR is highly sensitive and complementary to IHC as it also recognizes other mutations besides V600E and it is suitable for diagnostic purposes.

  14. High efficiency lighting: Cost benefit analysis

    Energy Technology Data Exchange (ETDEWEB)

    Di Franco, N. (ENEA, Rome (Italy))


    Analysis of the incandescent and fluorescent lamp market in Italy reveals that, by the substitution of conventional equipment with high efficiency lamps, energy savings of up to 3.5 billion kWh could be realized. However, the proper selection of these highly efficient lamps, e.g., compact fluorescent, fluorescent systems using electronic reactors, outdoor systems using sodium or metal iodides, etc., requires a thorough and accurate cost benefit analysis. This article suggests a calculation model for a cost evaluation beginning from the technical and economic aspects of alternative appliances.

  15. Measure Guideline. High Efficiency Natural Gas Furnaces

    Energy Technology Data Exchange (ETDEWEB)

    Brand, L. [Partnership for Advanced Residential Retrofit (PARR), Des Plaines, IL (United States); Rose, W. [Partnership for Advanced Residential Retrofit (PARR), Des Plaines, IL (United States)


    This measure guideline covers installation of high-efficiency gas furnaces, including: when to install a high-efficiency gas furnace as a retrofit measure; how to identify and address risks; and the steps to be used in the selection and installation process. The guideline is written for Building America practitioners and HVAC contractors and installers. It includes a compilation of information provided by manufacturers, researchers, and the Department of Energy as well as recent research results from the Partnership for Advanced Residential Retrofit (PARR) Building America team.

  16. Measure Guideline: High Efficiency Natural Gas Furnaces

    Energy Technology Data Exchange (ETDEWEB)

    Brand, L.; Rose, W.


    This Measure Guideline covers installation of high-efficiency gas furnaces. Topics covered include when to install a high-efficiency gas furnace as a retrofit measure, how to identify and address risks, and the steps to be used in the selection and installation process. The guideline is written for Building America practitioners and HVAC contractors and installers. It includes a compilation of information provided by manufacturers, researchers, and the Department of Energy as well as recent research results from the Partnership for Advanced Residential Retrofit (PARR) Building America team.

  17. Detection of Escherichia coli O157 by peptide nucleic acid fluorescence in situ hybridization (PNA-FISH) and comparison to a standard culture method. (United States)

    Almeida, C; Sousa, J M; Rocha, R; Cerqueira, L; Fanning, S; Azevedo, N F; Vieira, M J


    Despite the emergence of non-O157 Shiga toxin-producing Escherichia coli (STEC) infections, E. coli serotype O157 is still the most commonly identified STEC in the world. It causes high morbidity and mortality and has been responsible for a number of outbreaks in many parts of the world. Various methods have been developed to detect this particular serotype, but standard bacteriological methods remain the gold standard. Here, we propose a new peptide nucleic acid fluorescence in situ hybridization (PNA-FISH) method for the rapid detection of E. coli O157. Testing on 54 representative strains showed that the PNA probe is highly sensitive and specific to E. coli O157. The method then was optimized for detection in food samples. Ground beef and unpasteurized milk samples were artificially contaminated with E. coli O157 concentrations ranging from 1 × 10(-2) to 1 × 10(2) CFU per 25 g or ml of food. Samples were then preenriched and analyzed by both the traditional bacteriological method (ISO 16654:2001) and PNA-FISH. The PNA-FISH method performed well in both types of food matrices with a detection limit of 1 CFU/25 g or ml of food samples. Tests on 60 food samples have shown a specificity value of 100% (95% confidence interval [CI], 82.83 to 100), a sensitivity of 97.22% (95% CI, 83.79 to 99.85%), and an accuracy of 98.33% (CI 95%, 83.41 to 99.91%). Results indicate that PNA-FISH performed as well as the traditional culture methods and can reduce the diagnosis time to 1 day.

  18. Novel Nanophosphors for High Efficiency Fluorescent Lamps

    Energy Technology Data Exchange (ETDEWEB)

    Alok M. Srivastava


    This is the Yearly Report of the Novel Nanophosphors for High Efficiency Fluorescent Lamps, Department of Energy (DOE). The overall goal of this three-year program is to develop novel hybrid phosphors by coating commercially available lamp phosphors with highly stable wide band-gap nanocrystalline phosphors (NCP). The novel hybrid phosphors will increase the efficiency of the fluorescent lamps by up to 32%, enabling total energy savings of 0.26 quads, the reduction in the U.S. energy bill by $6.5 billion and the reduction of the annual carbon emission by 4.1 billion kilogram. The prime technical approach is the development of NCP quantum-splitting phosphor (QSP) and ultra-violet emitting phosphors with quantum efficiencies exceeding that of the conventional phosphors at 185 nm. Our chief achievement, during the current contract period, pertains to the successful synthesis and characterization of coated phosphors. We demonstrated several synthesis techniques for the coating of micron sized commercial phosphors with quantum-splitting and UV emitting nanophosphors. We have also continued our fundamental investigations into the physical processes that determine the quantum efficiency of the nanophosphors and this has further helped codify a set of rules for the host lattice that support efficient quantum splitting and UV emission at room temperature. In this report we summarize the technical work completed under the Program, summarize our findings about the performance limits of the various technologies we investigated, and outline promising paths for future work.

  19. Highly efficient, gearless drive; Hocheffizienter, getriebeloser Antrieb

    Energy Technology Data Exchange (ETDEWEB)

    Niederer, R.


    Highly efficient, gearless variable-speed drive systems for low-speed applications have been developed. These systems consist of an inverter with active switches (IGBTs, MOSFETs, resp.) and a synchronous machine excited with permanent magnets. Therefore, these systems can be used for drive as well as for generator applications. They operate very efficiently since a gearbox is obsolete, furthermore weight, dimensions, noise and maintenance can be reduced. The inverter controllers do not require any speed sensors, thus reliability is increased and costs are decreased. Application for low-speed variable-speed drive systems can be found in industrial applications, cable railways or wind turbines. Both systems have been optimized in several iterative loops, in what regards overall efficiency and material expenditure. For both systems, prototypes have been developed and tested. Both prototypes performed reliably and fulfilled the expectations. The high power system (1200 kW, 20 rpm) operated at rated load with an overall efficiency of 93.1%, the lower power system (3 kW, 60 rpm) with an overall efficiency of 85%. Thus the losses of these new systems are at rated load about 4% lower compared to conventional drive systems equipped with a mechanical gearbox. (author)

  20. High Efficiency Solar Integrated Roof Membrane Product

    Energy Technology Data Exchange (ETDEWEB)

    Partyka, Eric; Shenoy, Anil


    This project was designed to address the Solar Energy Technology Program objective, to develop new methods to integrate photovoltaic (PV) cells or modules within a building-integrated photovoltaic (BIPV) application that will result in lower installed cost as well as higher efficiencies of the encapsulated/embedded PV module. The technology assessment and development focused on the evaluation and identification of manufacturing technologies and equipment capable of producing such low-cost, high-efficiency, flexible BIPV solar cells on single-ply roofing membranes.

  1. Adaptation of ubiquitin-PNA based sperm quality assay for semen evaluation by a conventional flow cytometer and a dedicated platform for flow cytometric semen analysis. (United States)

    Odhiambo, J F; Sutovsky, M; DeJarnette, J M; Marshall, C; Sutovsky, P


    The purpose of semen quality evaluation is to predict the fertility potential of the sample in an objective, rapid and inexpensive manner. However, utilization of sperm quality biomarkers such as ubiquitin and lectin Arachis hypogaea agglutinin (PNA) for flow cytometric semen evaluation might eliminate the need for visual assessment by microscopy. Herein, we demonstrate a robust ubiquitin and PNA-based semen evaluation conducted on a simple, easy to operate, dedicated sperm flow cytometer, EasyCyte Plus (IMV Technologies, L'Aigle, France). Semen samples were collected periodically from two dairy bulls, which were subjected to temporary scrotal insults to induce variable semen quality. Samples were labeled with fluorescently-conjugated anti-ubiquitin antibodies (bind exclusively to the surface of defective sperm) and lectin PNA (binds to acrosomal surface in prematurely capacitated and acrosome-damaged sperm). Fluorescent properties of the samples were measured with a conventional flow cytometer (Becton Dickinson FACScan; Becton Dickinson Corp., Franklin Lakes, NJ, USA) and by the EasyCyte (IMV Technologies) instrument. Data from the two flow cytometers were positively correlated for the percentage of PNA-positive sperm with a damaged acrosome (r = 0.47; P < 0.001) and the percentage of ubiquitin-positive, defective sperm (r = 0.68; P < 0.001). Relative intensities of ubiquitin-induced fluorescence in cells with high ubiquitin levels were also positively correlated (r = 0.90). The proportion of sperm with abnormal morphology was positively correlated with ubiquitin-induced fluorescence measured by EasyCyte (IMV Technologies) (r = 0.63; P < 0.001). These observations provided a rationale for the adaptation of a dual ubiquitin-PNA sperm quality assay for flow cytometric semen evaluation. Copyright © 2011 Elsevier Inc. All rights reserved.

  2. Programming the formation of DNA and PNA quadruplexes by π-π-stacking interaction†


    Saha, Sourav; Cai, Jianfeng; Eiler, Daniel; Hamilton, Andrew D.


    Guanine (G) rich G4T4G4 DNA and homologous PNA strands tend to form antiparallel dimeric quadruplexes, which can be hybridized to form a stable parallel DNA2PNA2 hybrid quadruplex. In contrast, the same DNA strands functionalised with large planar aromatic groups at the 5′-end lead to the formation of parallel DNA quadruplex, which cannot be perturbed by homologous PNA strands. Conformation and composition of the DNA quadruplexes can be programed by π-π-stacking interaction.

  3. High Efficiency Reversible Fuel Cell Power Converter

    DEFF Research Database (Denmark)

    Pittini, Riccardo

    The large scale integration of renewable energy sources requires suitable energy storage systems to balance energy production and demand in the electrical grid. Bidirectional fuel cells are an attractive technology for energy storage systems due to the high energy density of fuel. Compared...... to traditional unidirectional fuel cell, bidirectional fuel cells have increased operating voltage and current ranges. These characteristics increase the stresses on dc-dc and dc-ac converters in the electrical system, which require proper design and advanced optimization. This work is part of the PhD project...... entitled "High Efficiency Reversible Fuel Cell Power Converter" and it presents the design of a high efficiency dc-dc converter developed and optimized for bidirectional fuel cell applications. First, a brief overview of fuel cell and energy storage technologies is presented. Different system topologies...

  4. Methodologies for high efficiency perovskite solar cells. (United States)

    Park, Nam-Gyu


    Since the report on long-term durable solid-state perovskite solar cell in 2012, perovskite solar cells based on lead halide perovskites having organic cations such as methylammonium CH3NH3PbI3 or formamidinium HC(NH2)2PbI3 have received great attention because of superb photovoltaic performance with power conversion efficiency exceeding 22 %. In this review, emergence of perovskite solar cell is briefly introduced. Since understanding fundamentals of light absorbers is directly related to their photovoltaic performance, opto-electronic properties of organo lead halide perovskites are investigated in order to provide insight into design of higher efficiency perovskite solar cells. Since the conversion efficiency of perovskite solar cell is found to depend significantly on perovskite film quality, methodologies for fabricating high quality perovskite films are particularly emphasized, including various solution-processes and vacuum deposition method.

  5. Complexity-aware high efficiency video coding

    CERN Document Server

    Correa, Guilherme; Agostini, Luciano; Cruz, Luis A da Silva


    This book discusses computational complexity of High Efficiency Video Coding (HEVC) encoders with coverage extending from the analysis of HEVC compression efficiency and computational complexity to the reduction and scaling of its encoding complexity. After an introduction to the topic and a review of the state-of-the-art research in the field, the authors provide a detailed analysis of the HEVC encoding tools compression efficiency and computational complexity.  Readers will benefit from a set of algorithms for scaling the computational complexity of HEVC encoders, all of which take advantage from the flexibility of the frame partitioning structures allowed by the standard.  The authors also provide a set of early termination methods based on data mining and machine learning techniques, which are able to reduce the computational complexity required to find the best frame partitioning structures. The applicability of the proposed methods is finally exemplified with an encoding time control system that emplo...

  6. High Efficiency, Low Emission Refrigeration System

    Energy Technology Data Exchange (ETDEWEB)

    Fricke, Brian A [ORNL; Sharma, Vishaldeep [ORNL


    Supermarket refrigeration systems account for approximately 50% of supermarket energy use, placing this class of equipment among the highest energy consumers in the commercial building domain. In addition, the commonly used refrigeration system in supermarket applications is the multiplex direct expansion (DX) system, which is prone to refrigerant leaks due to its long lengths of refrigerant piping. This leakage reduces the efficiency of the system and increases the impact of the system on the environment. The high Global Warming Potential (GWP) of the hydrofluorocarbon (HFC) refrigerants commonly used in these systems, coupled with the large refrigerant charge and the high refrigerant leakage rates leads to significant direct emissions of greenhouse gases into the atmosphere. Methods for reducing refrigerant leakage and energy consumption are available, but underutilized. Further work needs to be done to reduce costs of advanced system designs to improve market utilization. In addition, refrigeration system retrofits that result in reduced energy consumption are needed since the majority of applications address retrofits rather than new stores. The retrofit market is also of most concern since it involves large-volume refrigerant systems with high leak rates. Finally, alternative refrigerants for new and retrofit applications are needed to reduce emissions and reduce the impact on the environment. The objective of this Collaborative Research and Development Agreement (CRADA) between the Oak Ridge National Laboratory and Hill Phoenix is to develop a supermarket refrigeration system that reduces greenhouse gas emissions and has 25 to 30 percent lower energy consumption than existing systems. The outcomes of this project will include the design of a low emission, high efficiency commercial refrigeration system suitable for use in current U.S. supermarkets. In addition, a prototype low emission, high efficiency supermarket refrigeration system will be produced for

  7. Breeding for high water-use efficiency. (United States)

    Condon, A G; Richards, R A; Rebetzke, G J; Farquhar, G D


    There is a pressing need to improve the water-use efficiency of rain-fed and irrigated crop production. Breeding crop varieties with higher water-use efficiency is seen as providing part of the solution. Three key processes can be exploited in breeding for high water-use efficiency: (i) moving more of the available water through the crop rather than it being wasted as evaporation from the soil surface or drainage beyond the root zone or being left behind in the root zone at harvest; (ii) acquiring more carbon (biomass) in exchange for the water transpired by the crop, i.e. improving crop transpiration efficiency; (iii) partitioning more of the achieved biomass into the harvested product. The relative importance of any one of these processes will vary depending on how water availability varies during the crop cycle. However, these three processes are not independent. Targeting specific traits to improve one process may have detrimental effects on the other two, but there may also be positive interactions. Progress in breeding for improved water-use efficiency of rain-fed wheat is reviewed to illustrate the nature of some of these interactions and to highlight opportunities that may be exploited in other crops as well as potential pitfalls. For C3 species, measuring carbon isotope discrimination provides a powerful means of improving water-use efficiency of leaf gas exchange, but experience has shown that improvements in leaf-level water-use efficiency may not always translate into higher crop water-use efficiency or yield. In fact, the reverse has frequently been observed. Reasons for this are explored in some detail. Crop simulation modelling can be used to assess the likely impact on water-use efficiency and yield of changing the expression of traits of interest. Results of such simulations indicate that greater progress may be achieved by pyramiding traits so that potential negative effects of individual traits are neutralized. DNA-based selection techniques may

  8. Synthesis and Chromatography-Free Purification of PNA-PEO Conjugates for the Functionalisation of Gold Sensors

    Directory of Open Access Journals (Sweden)

    Filippo Romanato


    Full Text Available Peptide Nucleic Acids (PNAs linked to high molecular weight (MW poly(ethylene oxide (PEO derivatives could be useful conjugates for the direct functionalisation of gold surfaces dedicated to Surface Plasmon Resonance (SPR-based DNA sensing. However their use is hampered by the difficulty to obtain them through a convenient and economical route. In this work we compared three synthetic strategies to obtain PNA-high MW PEO conjugates composed of (a a 15-mer PNA sequence as the probe complementary to genomic DNA of Mycobacterium tuberculosis, (b a PEO moiety (2 or 5 KDa MW and (c a terminal trityl-protected thiol necessary (after acidic deprotection for grafting to gold surfaces. The 15-mer PNA was obtained by solid-phase synthesis. Its amino terminal group was later condensed to bi-functional PEO derivatives (2 and 5 KDa MW carrying a Trt-cysteine at one end and a carboxyl group at the other end. The reaction was carried out either in solution, using HATU or PyOxim as coupling agents, or through the solid-phase approach, with 49.6%, 100% and 5.2% yield, respectively. A differential solvent extraction strategy for product purification without the need for chromatography is described. The ability of the 5 KDa PEO conjugate to function as a probe for complementary DNA detection was demonstrated using a Grating-Coupling Surface Plasmon Resonance (GC-SPR system. The optimized PEO conjugation and purification protocols are economical and simple enough to be reproduced also within laboratories that are not highly equipped for chemical synthesis.

  9. Synthesis and chromatography-free purification of PNA-PEO conjugates for the functionalisation of gold sensors. (United States)

    Dettin, Monica; Silvestri, Davide; Danesin, Roberta; Cretaio, Erica; Picariello, Gianluca; Casarin, Elisabetta; Sonato, Agnese; Romanato, Filippo; Morpurgo, Margherita


    Peptide Nucleic Acids (PNAs) linked to high molecular weight (MW) poly(ethylene oxide) (PEO) derivatives could be useful conjugates for the direct functionalisation of gold surfaces dedicated to Surface Plasmon Resonance (SPR)-based DNA sensing. However their use is hampered by the difficulty to obtain them through a convenient and economical route. In this work we compared three synthetic strategies to obtain PNA-high MW PEO conjugates composed of (a) a 15-mer PNA sequence as the probe complementary to genomic DNA of ]Mycobacterium tuberculosis, (b) a PEO moiety (2 or 5 KDa MW) and (c) a terminal trityl-protected thiol necessary (after acidic deprotection) for grafting to gold surfaces. The 15-mer PNA was obtained by solid-phase synthesis. Its amino terminal group was later condensed to bi-functional PEO derivatives (2 and 5 KDa MW) carrying a Trt-cysteine at one end and a carboxyl group at the other end. The reaction was carried out either in solution, using HATU or PyOxim as coupling agents, or through the solid-phase approach, with 49.6%, 100% and 5.2% yield, respectively. A differential solvent extraction strategy for product purification without the need for chromatography is described. The ability of the 5 KDa PEO conjugate to function as a probe for complementary DNA detection was demonstrated using a Grating-Coupling Surface Plasmon Resonance (GC-SPR) system. The optimized PEO conjugation and purification protocols are economical and simple enough to be reproduced also within laboratories that are not highly equipped for chemical synthesis.

  10. Bioblendstocks that Enable High Efficiency Engine Designs

    Energy Technology Data Exchange (ETDEWEB)

    McCormick, Robert L.; Fioroni, Gina M.; Ratcliff, Matthew A.; Zigler, Bradley T.; Farrell, John


    The past decade has seen a high level of innovation in production of biofuels from sugar, lipid, and lignocellulose feedstocks. As discussed in several talks at this workshop, ethanol blends in the E25 to E50 range could enable more highly efficient spark-ignited (SI) engines. This is because of their knock resistance properties that include not only high research octane number (RON), but also charge cooling from high heat of vaporization, and high flame speed. Emerging alcohol fuels such as isobutanol or mixed alcohols have desirable properties such as reduced gasoline blend vapor pressure, but also have lower RON than ethanol. These fuels may be able to achieve the same knock resistance benefits, but likely will require higher blend levels or higher RON hydrocarbon blendstocks. A group of very high RON (>150) oxygenates such as dimethyl furan, methyl anisole, and related compounds are also produced from biomass. While providing no increase in charge cooling, their very high octane numbers may provide adequate knock resistance for future highly efficient SI engines. Given this range of options for highly knock resistant fuels there appears to be a critical need for a fuel knock resistance metric that includes effects of octane number, heat of vaporization, and potentially flame speed. Emerging diesel fuels include highly branched long-chain alkanes from hydroprocessing of fats and oils, as well as sugar-derived terpenoids. These have relatively high cetane number (CN), which may have some benefits in designing more efficient CI engines. Fast pyrolysis of biomass can produce diesel boiling range streams that are high in aromatic, oxygen and acid contents. Hydroprocessing can be applied to remove oxygen and consequently reduce acidity, however there are strong economic incentives to leave up to 2 wt% oxygen in the product. This oxygen will primarily be present as low CN alkyl phenols and aryl ethers. While these have high heating value, their presence in diesel fuel

  11. Highly efficient fully transparent inverted OLEDs (United States)

    Meyer, J.; Winkler, T.; Hamwi, S.; Schmale, S.; Kröger, M.; Görrn, P.; Johannes, H.-H.; Riedl, T.; Lang, E.; Becker, D.; Dobbertin, T.; Kowalsky, W.


    One of the unique selling propositions of OLEDs is their potential to realize highly transparent devices over the visible spectrum. This is because organic semiconductors provide a large Stokes-Shift and low intrinsic absorption losses. Hence, new areas of applications for displays and ambient lighting become accessible, for instance, the integration of OLEDs into the windshield or the ceiling of automobiles. The main challenge in the realization of fully transparent devices is the deposition of the top electrode. ITO is commonly used as transparent bottom anode in a conventional OLED. To obtain uniform light emission over the entire viewing angle and a low series resistance, a TCO such as ITO is desirable as top contact as well. However, sputter deposition of ITO on top of organic layers causes damage induced by high energetic particles and UV radiation. We have found an efficient process to protect the organic layers against the ITO rf magnetron deposition process of ITO for an inverted OLED (IOLED). The inverted structure allows the integration of OLEDs in more powerful n-channel transistors used in active matrix backplanes. Employing the green electrophosphorescent material Ir(ppy) 3 lead to IOLED with a current efficiency of 50 cd/A and power efficiency of 24 lm/W at 100 cd/m2. The average transmittance exceeds 80 % in the visible region. The on-set voltage for light emission is lower than 3 V. In addition, by vertical stacking we achieved a very high current efficiency of more than 70 cd/A for transparent IOLED.

  12. High Efficiency Colloidal Quantum Dot Phosphors

    Energy Technology Data Exchange (ETDEWEB)

    Kahen, Keith


    The project showed that non-Cd containing, InP-based nanocrystals (semiconductor materials with dimensions of ~6 nm) have high potential for enabling next-generation, nanocrystal-based, on chip phosphors for solid state lighting. Typical nanocrystals fall short of the requirements for on chip phosphors due to their loss of quantum efficiency under the operating conditions of LEDs, such as, high temperature (up to 150 °C) and high optical flux (up to 200 W/cm2). The InP-based nanocrystals invented during this project maintain high quantum efficiency (>80%) in polymer-based films under these operating conditions for emission wavelengths ranging from ~530 to 620 nm. These nanocrystals also show other desirable attributes, such as, lack of blinking (a common problem with nanocrystals which limits their performance) and no increase in the emission spectral width from room to 150 °C (emitters with narrower spectral widths enable higher efficiency LEDs). Prior to these nanocrystals, no nanocrystal system (regardless of nanocrystal type) showed this collection of properties; in fact, other nanocrystal systems are typically limited to showing only one desirable trait (such as high temperature stability) but being deficient in other properties (such as high flux stability). The project showed that one can reproducibly obtain these properties by generating a novel compositional structure inside of the nanomaterials; in addition, the project formulated an initial theoretical framework linking the compositional structure to the list of high performance optical properties. Over the course of the project, the synthetic methodology for producing the novel composition was evolved to enable the synthesis of these nanomaterials at a cost approximately equal to that required for forming typical conventional nanocrystals. Given the above results, the last major remaining step prior to scale up of the nanomaterials is to limit the oxidation of these materials during the tens of

  13. Quantum wells for high-efficiency photovoltaics (United States)

    Alonso-Álvarez, Diego; Ekins-Daukes, Nicholas


    Over the last couple of decades, there has been an intense research on strain balanced semiconductor quantum wells (QW) to increase the efficiency of multi-junction solar (MJ) solar cells grown monolithically on germanium. So far, the most successful application of QWs have required just to tailor a few tens of nanometers the absorption edge of a given subcell in order to reach the optimum spectral position. However, the demand for higher efficiency devices requiring 3, 4 or more junctions, represents a major difference in the challenges QWs must face: tailoring the absorption edge of a host material is not enough, but a complete new device, absorbing light in a different spectral region, must be designed. Among the most important issues to solve is the need for an optically thick structure to absorb enough light while keeping excellent carrier extraction using highly strained materials. Improvement of the growth techniques, smarter device designs - involving superlattices and shifted QWs, for example - or the use of quantum wires rather than QWs, have proven to be very effective steps towards high efficient MJ solar cells based on nanostructures in the last couple of years. But more is to be done to reach the target performances. This work discusses all these challenges, the limitations they represent and the different approaches that are being used to overcome them.

  14. High efficiency motors; Motores de alta eficiencia

    Energy Technology Data Exchange (ETDEWEB)

    Uranga Favela, Ivan Jaime [Energia Controlada de Mexico, S. A. de C. V., Mexico, D. F. (Mexico)


    This paper is a technical-financial study of the high efficiency and super-premium motors. As it is widely known, more than 60% of the electrical energy generated in the country is used for the operation of motors, in industry as well as in commerce. Therefore the importance that the motors have in the efficient energy use. [Espanol] El presente trabajo es un estudio tecnico-financiero de los motores de alta eficiencia y los motores super premium. Como es ampliamente conocido, mas del 60% de la energia electrica generada en el pais, es utilizada para accionar motores, dentro de la industria y el comercio. De alli la importancia que los motores tienen en el uso eficiente de la energia.

  15. High-efficiency organic glass scintillators

    Energy Technology Data Exchange (ETDEWEB)

    Feng, Patrick L.; Carlson, Joseph S.


    A new family of neutron/gamma discriminating scintillators is disclosed that comprises stable organic glasses that may be melt-cast into transparent monoliths. These materials have been shown to provide light yields greater than solution-grown trans-stilbene crystals and efficient PSD capabilities when combined with 0.01 to 0.05% by weight of the total composition of a wavelength-shifting fluorophore. Photoluminescence measurements reveal fluorescence quantum yields that are 2 to 5 times greater than conventional plastic or liquid scintillator matrices, which accounts for the superior light yield of these glasses. The unique combination of high scintillation light-yields, efficient neutron/gamma PSD, and straightforward scale-up via melt-casting distinguishes the developed organic glasses from existing scintillators.

  16. High Efficiency Power Converter for Low Voltage High Power Applications

    DEFF Research Database (Denmark)

    Nymand, Morten

    and maximum output power. In chapter 3, a detailed analysis of dominant loss factors in high power converters for low voltage applications is presented. The analysis concludes that: • Power transformers for low voltage high power, if properly designed, will have extremely low leakage inductance......The topic of this thesis is the design of high efficiency power electronic dc-to-dc converters for high-power, low-input-voltage to high-output-voltage applications. These converters are increasingly required for emerging sustainable energy systems such as fuel cell, battery or photo voltaic based....... • If optimally designed, boost converters will be much more efficient than comparable buck type converters for high power low voltage applications. • The use of voltage clamp circuits to protect primary switches in boost converters is no longer needed for device protection. On the other hand...

  17. Charging-discharging system with high power factor, high efficiency

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Eun Soo; Joe, Kee Yeon; Byun, Young Bok; Koo, Heun Hoi [Korea Electrotechnology Research Institute (Korea, Republic of)


    This paper presents equipment for charging and discharging with high power factor and high efficiency. This equipment is consisted of 3{Phi} SPWM AC/DC converter for improving input current waveform and input power factor, and bidirectional DC/DC converter for electric isolation in the DC link Part. Therefore, Input power factor and the total efficiency in the proposed system can be increased more than in the conventional phase-controlled thyristor charging-discharging System. (author). 7 refs., 14 figs., 1 tab.

  18. High Quantum Efficiency OLED Lighting Systems

    Energy Technology Data Exchange (ETDEWEB)

    Shiang, Joseph [General Electric (GE) Global Research, Fairfield, CT (United States)


    The overall goal of the program was to apply improvements in light outcoupling technology to a practical large area plastic luminaire, and thus enable the product vision of an extremely thin form factor high efficiency large area light source. The target substrate was plastic and the baseline device was operating at 35 LPW at the start of the program. The target LPW of the program was a >2x improvement in the LPW efficacy and the overall amount of light to be delivered was relatively high 900 lumens. Despite the extremely difficult challenges associated with scaling up a wet solution process on plastic substrates, the program was able to make substantial progress. A small molecule wet solution process was successfully implemented on plastic substrates with almost no loss in efficiency in transitioning from the laboratory scale glass to large area plastic substrates. By transitioning to a small molecule based process, the LPW entitlement increased from 35 LPW to 60 LPW. A further 10% improvement in outcoupling efficiency was demonstrated via the use of a highly reflecting cathode, which reduced absorptive loss in the OLED device. The calculated potential improvement in some cases is even larger, ~30%, and thus there is considerable room for optimism in improving the net light coupling efficacy, provided absorptive loss mechanisms are eliminated. Further improvements are possible if scattering schemes such as the silver nanowire based hard coat structure are fully developed. The wet coating processes were successfully scaled to large area plastic substrate and resulted in the construction of a 900 lumens luminaire device.

  19. Nanooptics for high efficient photon managment (United States)

    Wyrowski, Frank; Schimmel, Hagen


    Optical systems for photon management, that is the generation of tailored electromagnetic fields, constitute one of the keys for innovation through photonics. An important subfield of photon management deals with the transformation of an incident light field into a field of specified intensity distribution. In this paper we consider some basic aspects of the nature of systems for those light transformations. It turns out, that the transversal redistribution of energy (TRE) is of central concern to achieve systems with high transformation efficiency. Besides established techniques nanostructured optical elements (NOE) are demanded to implement transversal energy redistribution. That builds a bridge between the needs of photon management, optical engineering, and nanooptics.

  20. Highly Efficient Prion Transmission by Blood Transfusion (United States)

    Andréoletti, Olivier; Litaise, Claire; Simmons, Hugh; Corbière, Fabien; Lugan, Séverine; Costes, Pierrette; Schelcher, François; Vilette, Didier; Grassi, Jacques; Lacroux, Caroline


    It is now clearly established that the transfusion of blood from variant CJD (v-CJD) infected individuals can transmit the disease. Since the number of asymptomatic infected donors remains unresolved, inter-individual v-CJD transmission through blood and blood derived products is a major public health concern. Current risk assessments for transmission of v-CJD by blood and blood derived products by transfusion rely on infectious titers measured in rodent models of Transmissible Spongiform Encephalopathies (TSE) using intra-cerebral (IC) inoculation of blood components. To address the biological relevance of this approach, we compared the efficiency of TSE transmission by blood and blood components when administrated either through transfusion in sheep or by intra-cerebral inoculation (IC) in transgenic mice (tg338) over-expressing ovine PrP. Transfusion of 200 µL of blood from asymptomatic infected donor sheep transmitted prion disease with 100% efficiency thereby displaying greater virulence than the transfusion of 200 mL of normal blood spiked with brain homogenate material containing 103ID50 as measured by intracerebral inoculation of tg338 mice (ID50 IC in tg338). This was consistent with a whole blood titer greater than 103.6 ID50 IC in tg338 per mL. However, when the same blood samples were assayed by IC inoculation into tg338 the infectious titers were less than 32 ID per mL. Whereas the transfusion of crude plasma to sheep transmitted the disease with limited efficacy, White Blood Cells (WBC) displayed a similar ability to whole blood to infect recipients. Strikingly, fixation of WBC with paraformaldehyde did not affect the infectivity titer as measured in tg338 but dramatically impaired disease transmission by transfusion in sheep. These results demonstrate that TSE transmission by blood transfusion can be highly efficient and that this efficiency is more dependent on the viability of transfused cells than the level of infectivity measured by IC

  1. Simple Motor Control Concept Results High Efficiency at High Velocities (United States)

    Starin, Scott; Engel, Chris


    The need for high velocity motors in space applications for reaction wheels and detectors has stressed the limits of Brushless Permanent Magnet Motors (BPMM). Due to inherent hysteresis core losses, conventional BPMMs try to balance the need for torque verses hysteresis losses. Cong-less motors have significantly less hysteresis losses but suffer from lower efficiencies. Additionally, the inherent low inductance in cog-less motors result in high ripple currents or high switching frequencies, which lowers overall efficiency and increases performance demands on the control electronics.However, using a somewhat forgotten but fully qualified technology of Isotropic Magnet Motors (IMM), extremely high velocities may be achieved at low power input using conventional drive electronics. This paper will discuss the trade study efforts and empirical test data on a 34,000 RPM IMM.

  2. High efficiency dielectric metasurfaces at visible wavelengths

    CERN Document Server

    Devlin, Robert C; Chen, Wei-Ting; Oh, Jaewon; Capasso, Federico


    Metasurfaces are planar optical elements that hold promise for overcoming the limitations of refractive and conventional diffractive optics1-3. Dielectric metasurfaces demonstrated thus far4-10 are limited to transparency windows at infrared wavelengths because of significant optical absorption and loss at visible wavelengths. It is critical that new materials and fabrication techniques be developed for dielectric metasurfaces at visible wavelengths to enable applications such as three-dimensional displays, wearable optics and planar optical systems11. Here, we demonstrate high performance titanium dioxide dielectric metasurfaces in the form of holograms for red, green and blue wavelengths with record absolute efficiency (>78%). We use atomic layer deposition of amorphous titanium dioxide that exhibits low surface roughness of 0.738 nm and ideal optical properties. To fabricate the metasurfaces we use a lift-off-like process that allows us to produce highly anisotropic nanofins with shape birefringence. This ...

  3. Novel Nanophosphors for High Efficiency Fluorescent Lamps

    Energy Technology Data Exchange (ETDEWEB)

    Alok Srivatava


    This is the Final Report of the Novel Nanophosphors for High Efficiency Fluorescent Lamps, Department of Energy (DOE). The overall goal of this three-year program is to develop novel hybrid phosphors by coating commercially available lamp phosphors with highly stable wide band-gap nanocrystalline phosphors (NCP). The prime technical approach is the development of NCP quantum-splitting phosphor (QSP) and ultra-violet (UV) emitting phosphors with quantum efficiencies exceeding that of the conventional phosphors at 185 nm. The novel hybrid phosphors will increase the efficiency of the fluorescent lamps by up to 32%, enabling total energy savings of 0.26 quads, the reduction in the U.S. energy bill by $6.5 billion and the reduction of the annual carbon emission by 4.1 billion kilogram. Our work started by investigating through modeling calculations the requirement for the particle size of the NCP. Our work to develop suitable nanocrystalline phosphors started with the known oxide quantum splitting and UV emitting phosphors. We demonstrated several synthesis techniques for the production of high quality nanocrystalline materials that crystallizes in the desired phase and with the desired particle size. In collaboration with our subcontractor we demonstrated the feasibility for the manufacture of NC phosphors. We also demonstrated novel techniques of coating the NCP on the surface of micron sized phosphors. Our chief achievement pertains to the successful testing of the coated hybrid phosphor systems in linear fluorescent lamps. In linear fluorescent lamp tests, we have demonstrated up to 7% increase in the efficacy of hybrid phosphors over the conventional (uncoated) phosphors. We have also demonstrated the improvement in the lumen maintenance of the coated phosphors. A hybrid phosphor system based on the commercial red emitting phosphor, Y{sub 2}O{sub 3}:Eu{sup 3+} did not show the anticipated improvement in lamp efficacy. We explored the reasons for this observation

  4. Highly Efficient Vector-Inversion Pulse Generators (United States)

    Rose, Franklin


    Improved transmission-line pulse generators of the vector-inversion type are being developed as lightweight sources of pulsed high voltage for diverse applications, including spacecraft thrusters, portable x-ray imaging systems, impulse radar systems, and corona-discharge systems for sterilizing gases. In this development, more than the customary attention is paid to principles of operation and details of construction so as to the maximize the efficiency of the pulse-generation process while minimizing the sizes of components. An important element of this approach is segmenting a pulse generator in such a manner that the electric field in each segment is always below the threshold for electrical breakdown. One design of particular interest, a complete description of which was not available at the time of writing this article, involves two parallel-plate transmission lines that are wound on a mandrel, share a common conductor, and are switched in such a manner that the pulse generator is divided into a "fast" and a "slow" section. A major innovation in this design is the addition of ferrite to the "slow" section to reduce the size of the mandrel needed for a given efficiency.

  5. Identification of PCR-amplified genetically modified organisms (GMOs) DNA by peptide nucleic acid (PNA) probes in anion-exchange chromatographic analysis. (United States)

    Rossi, Stefano; Lesignoli, Francesca; Germini, Andrea; Faccini, Andrea; Sforza, Stefano; Corradini, Roberto; Marchelli, Rosangela


    PCR products obtained by selective amplification of transgenic DNA derived from food samples containing Roundup Ready soybean or Bt-176 maize have been analyzed by anion-exchange HPLC. Peptide nucleic acids (PNAs), oligonucleotide analogues known to bind to complementary single-stranded DNA with high affinity and specificity, have been used as specific probes in order to assess the identity of the peaks observed. Two different protocols were adopted in order to obtain single-stranded DNA: amplification with an excess of one primer or digestion of one DNA strand. The single-stranded DNA was mixed with the PNA probe, and the presence of a specific sequence was revealed through detection of the corresponding PNA:DNA peak with significantly different retention time. Advantages and limits of this approach are discussed. The method was tested with reference materials and subsequently applied to commercial samples.

  6. Design of High Efficient MPPT Solar Inverter

    Directory of Open Access Journals (Sweden)

    Sunitha K. A.


    Full Text Available This work aims to design a High Efficient Maximum Power Point Tracking (MPPT Solar Inverter. A boost converter is designed in the system to boost the power from the photovoltaic panel. By this experimental setup a room consisting of 500 Watts load (eight fluorescent tubes is completely controlled. It is aimed to decrease the maintenance cost. A microcontroller is introduced for tracking the P&O (Perturb and Observe algorithm used for tracking the maximum power point. The duty cycle for the operation of the boost convertor is optimally adjusted by using MPPT controller. There is a MPPT charge controller to charge the battery as well as fed to inverter which runs the load. Both the P&O scheme with the fixed variation for the reference current and the intelligent MPPT algorithm were able to identify the global Maximum power point, however the performance of the MPPT algorithm was better.

  7. High Efficiency Centrifugal Compressor for Rotorcraft Applications (United States)

    Medic, Gorazd; Sharma, Om P.; Jongwook, Joo; Hardin, Larry W.; McCormick, Duane C.; Cousins, William T.; Lurie, Elizabeth A.; Shabbir, Aamir; Holley, Brian M.; Van Slooten, Paul R.


    The report "High Efficiency Centrifugal Compressor for Rotorcraft Applications" documents the work conducted at UTRC under the NRA Contract NNC08CB03C, with cost share 2/3 NASA, and 1/3 UTRC, that has been extended to 4.5 years. The purpose of this effort was to identify key technical barriers to advancing the state-of-the-art of small centrifugal compressor stages; to delineate the measurements required to provide insight into the flow physics of the technical barriers; to design, fabricate, install, and test a state-of-the-art research compressor that is representative of the rear stage of an axial-centrifugal aero-engine; and to acquire detailed aerodynamic performance and research quality data to clarify flow physics and to establish detailed data sets for future application. The design activity centered on meeting the goal set outlined in the NASA solicitation-the design target was to increase efficiency at higher work factor, while also reducing the maximum diameter of the stage. To fit within the existing Small Engine Components Test Facility at NASA Glenn Research Center (GRC) and to facilitate component re-use, certain key design parameters were fixed by UTRC, including impeller tip diameter, impeller rotational speed, and impeller inlet hub and shroud radii. This report describes the design effort of the High Efficiency Centrifugal Compressor stage (HECC) and delineation of measurements, fabrication of the compressor, and the initial tests that were performed. A new High-Efficiency Centrifugal Compressor stage with a very challenging reduction in radius ratio was successfully designed, fabricated and installed at GRC. The testing was successful, with no mechanical problems and the running clearances were achieved without impeller rubs. Overall, measured pressure ratio of 4.68, work factor of 0.81, and at design exit corrected flow rate of 3 lbm/s met the target requirements. Polytropic efficiency of 85.5 percent and stall margin of 7.5 percent were

  8. White LED with High Package Extraction Efficiency

    Energy Technology Data Exchange (ETDEWEB)

    Yi Zheng; Matthew Stough


    The goal of this project is to develop a high efficiency phosphor converting (white) Light Emitting Diode (pcLED) 1-Watt package through an increase in package extraction efficiency. A transparent/translucent monolithic phosphor is proposed to replace the powdered phosphor to reduce the scattering caused by phosphor particles. Additionally, a multi-layer thin film selectively reflecting filter is proposed between blue LED die and phosphor layer to recover inward yellow emission. At the end of the project we expect to recycle approximately 50% of the unrecovered backward light in current package construction, and develop a pcLED device with 80 lm/W{sub e} using our technology improvements and commercially available chip/package source. The success of the project will benefit luminous efficacy of white LEDs by increasing package extraction efficiency. In most phosphor-converting white LEDs, the white color is obtained by combining a blue LED die (or chip) with a powdered phosphor layer. The phosphor partially absorbs the blue light from the LED die and converts it into a broad green-yellow emission. The mixture of the transmitted blue light and green-yellow light emerging gives white light. There are two major drawbacks for current pcLEDs in terms of package extraction efficiency. The first is light scattering caused by phosphor particles. When the blue photons from the chip strike the phosphor particles, some blue light will be scattered by phosphor particles. Converted yellow emission photons are also scattered. A portion of scattered light is in the backward direction toward the die. The amount of this backward light varies and depends in part on the particle size of phosphors. The other drawback is that yellow emission from phosphor powders is isotropic. Although some backward light can be recovered by the reflector in current LED packages, there is still a portion of backward light that will be absorbed inside the package and further converted to heat. Heat

  9. PNA-Peptide Assembly in a 3D DNA Nanocage at Room Temperature

    Energy Technology Data Exchange (ETDEWEB)

    Flory, Justin D. [Center; Shinde, Sandip [Center; Lin, Su [Center; Liu, Yan [Center; Yan, Hao [Center; Ghirlanda, Giovanna [Center; Fromme, Petra [Center


    Proteins and peptides fold into dynamic structures that access a broad functional landscape; however, designing artificial polypeptide systems is still a great challenge. Conversely, DNA engineering is now routinely used to build a wide variety of 2D and 3D nanostructures from hybridization based rules, and their functional diversity can be significantly expanded through site specific incorporation of the appropriate guest molecules. Here we demonstrate a new approach to rationally design 3D nucleic acid–amino acid complexes using peptide nucleic acid (PNA) to assemble peptides inside a 3D DNA nanocage. The PNA-peptides were found to bind to the preassembled DNA nanocage in 5–10 min at room temperature, and assembly could be performed in a stepwise fashion. Biophysical characterization of the DNA-PNA-peptide complex was performed using gel electrophoresis as well as steady state and time-resolved fluorescence spectroscopy. Based on these results we have developed a model for the arrangement of the PNA-peptides inside the DNA nanocage. This work demonstrates a flexible new approach to leverage rationally designed nucleic acid (DNA-PNA) nanoscaffolds to guide polypeptide engineering.

  10. Tailored Materials for High Efficiency CIDI Engines

    Energy Technology Data Exchange (ETDEWEB)

    Grant, G.J.; Jana, S.


    The overall goal of the project, Tailored Materials for High Efficiency Compression Ignition Direct Injection (CIDI) Engines, is to enable the implementation of new combustion strategies, such as homogeneous charge compression ignition (HCCI), that have the potential to significantly increase the energy efficiency of current diesel engines and decrease fuel consumption and environmental emissions. These strategies, however, are increasing the demands on conventional engine materials, either from increases in peak cylinder pressure (PCP) or from increases in the temperature of operation. The specific objective of this project is to investigate the application of a new material processing technology, friction stir processing (FSP), to improve the thermal and mechanical properties of engine components. The concept is to modify the surfaces of conventional, low-cost engine materials. The project focused primarily on FSP in aluminum materials that are compositional analogs to the typical piston and head alloys seen in small- to mid-sized CIDI engines. Investigations have been primarily of two types over the duration of this project: (1) FSP of a cast hypoeutectic Al-Si-Mg (A356/357) alloy with no introduction of any new components, and (2) FSP of Al-Cu-Ni alloys (Alloy 339) by physically stirring-in various quantities of carbon nanotubes/nanofibers or carbon fibers. Experimental work to date on aluminum systems has shown significant increases in fatigue lifetime and stress-level performance in aluminum-silicon alloys using friction processing alone, but work to demonstrate the addition of carbon nanotubes and fibers into aluminum substrates has shown mixed results due primarily to the difficulty in achieving porosity-free, homogeneous distributions of the particulate. A limited effort to understand the effects of FSP on steel materials was also undertaken during the course of this project. Processed regions were created in high-strength, low-alloyed steels up to 0.5 in

  11. High-efficiency multiphoton boson sampling (United States)

    Wang, Hui; He, Yu; Li, Yu-Huai; Su, Zu-En; Li, Bo; Huang, He-Liang; Ding, Xing; Chen, Ming-Cheng; Liu, Chang; Qin, Jian; Li, Jin-Peng; He, Yu-Ming; Schneider, Christian; Kamp, Martin; Peng, Cheng-Zhi; Höfling, Sven; Lu, Chao-Yang; Pan, Jian-Wei


    Boson sampling is considered as a strong candidate to demonstrate 'quantum computational supremacy' over classical computers. However, previous proof-of-principle experiments suffered from small photon number and low sampling rates owing to the inefficiencies of the single-photon sources and multiport optical interferometers. Here, we develop two central components for high-performance boson sampling: robust multiphoton interferometers with 99% transmission rate and actively demultiplexed single-photon sources based on a quantum dot-micropillar with simultaneously high efficiency, purity and indistinguishability. We implement and validate three-, four- and five-photon boson sampling, and achieve sampling rates of 4.96 kHz, 151 Hz and 4 Hz, respectively, which are over 24,000 times faster than previous experiments. Our architecture can be scaled up for a larger number of photons and with higher sampling rates to compete with classical computers, and might provide experimental evidence against the extended Church-Turing thesis.

  12. High efficiency diffusion molecular retention tumor targeting.

    Directory of Open Access Journals (Sweden)

    Yanyan Guo

    Full Text Available Here we introduce diffusion molecular retention (DMR tumor targeting, a technique that employs PEG-fluorochrome shielded probes that, after a peritumoral (PT injection, undergo slow vascular uptake and extensive interstitial diffusion, with tumor retention only through integrin molecular recognition. To demonstrate DMR, RGD (integrin binding and RAD (control probes were synthesized bearing DOTA (for (111 In(3+, a NIR fluorochrome, and 5 kDa PEG that endows probes with a protein-like volume of 25 kDa and decreases non-specific interactions. With a GFP-BT-20 breast carcinoma model, tumor targeting by the DMR or i.v. methods was assessed by surface fluorescence, biodistribution of [(111In] RGD and [(111In] RAD probes, and whole animal SPECT. After a PT injection, both probes rapidly diffused through the normal and tumor interstitium, with retention of the RGD probe due to integrin interactions. With PT injection and the [(111In] RGD probe, SPECT indicated a highly tumor specific uptake at 24 h post injection, with 352%ID/g tumor obtained by DMR (vs 4.14%ID/g by i.v.. The high efficiency molecular targeting of DMR employed low probe doses (e.g. 25 ng as RGD peptide, which minimizes toxicity risks and facilitates clinical translation. DMR applications include the delivery of fluorochromes for intraoperative tumor margin delineation, the delivery of radioisotopes (e.g. toxic, short range alpha emitters for radiotherapy, or the delivery of photosensitizers to tumors accessible to light.

  13. High bandgap III-V alloys for high efficiency optoelectronics

    Energy Technology Data Exchange (ETDEWEB)

    Alberi, Kirstin; Mascarenhas, Angelo; Wanlass, Mark


    High bandgap alloys for high efficiency optoelectronics are disclosed. An exemplary optoelectronic device may include a substrate, at least one Al.sub.1-xIn.sub.xP layer, and a step-grade buffer between the substrate and at least one Al.sub.1-xIn.sub.xP layer. The buffer may begin with a layer that is substantially lattice matched to GaAs, and may then incrementally increase the lattice constant in each sequential layer until a predetermined lattice constant of Al.sub.1-xIn.sub.xP is reached.

  14. Series-Tuned High Efficiency RF-Power Amplifiers

    DEFF Research Database (Denmark)

    Vidkjær, Jens


    An approach to high efficiency RF-power amplifier design is presented. It addresses simultaneously efficiency optimization and peak voltage limitations when transistors are pushed towards their power limits.......An approach to high efficiency RF-power amplifier design is presented. It addresses simultaneously efficiency optimization and peak voltage limitations when transistors are pushed towards their power limits....

  15. Comparative analysis of Gram's stain, PNA-FISH and Sepsityper with MALDI-TOF MS for the identification of yeast direct from positive blood cultures. (United States)

    Gorton, Rebecca L; Ramnarain, P; Barker, K; Stone, N; Rattenbury, S; McHugh, T D; Kibbler, C C


    Fungaemia diagnosis could be improved by reducing the time to identification of yeast from blood cultures. This study aimed to evaluate three rapid methods for the identification of yeast direct from blood cultures; Gram's stain analysis, the AdvanDX Peptide Nucleic Acid in Situ Hybridisation Yeast Traffic Light system (PNA-FISH YTL) and Bruker Sepsityper alongside matrix-assisted laser desorption ionisation time of flight mass spectrometry (MALDI-TOF MS). Fifty blood cultures spiked with a known single yeast strain were analysed by blinded operators experienced in each method. Identifications were compared with MALDI-TOF MS CHROMagar Candida culture and ITS rRNA sequence-based identifications. On first attempt, success rates of 96% (48/50) and 76% (36/50) were achieved using PNA-FISH YTL and Gram's stain respectively. MALDI-TOF MS demonstrated a success rate of 56% (28/50) when applying manufacturer's species log score thresholds and 76% (38/50) using in-house parameters, including lowering the species log score threshold to >1.5. In conclusion, PNA-FISH YTL demonstrated a high success rate successfully identifying yeast commonly encountered in fungaemia. Sepsityper(™) with MALDI-TOF MS was accurate but increased sensitivity is required. Due to the misidentification of commonly encountered yeast Gram's stain analysis demonstrated limited utility in this setting. © 2014 Blackwell Verlag GmbH.

  16. Site-selective scission of human genome using PNA-based artificial restriction DNA cutter. (United States)

    Ito, Kenichiro; Komiyama, Makoto


    Site-selective scission of genomes is quite important for future biotechnology. However, naturally occurring restriction enzymes cut these huge DNAs at too many sites and cannot be used for this purpose. Recently, we have developed a completely chemistry-based artificial restriction DNA cutter (ARCUT) by combining a pair of pseudo-complementary PNA (pcPNA) strands (sequence recognition moiety) and Ce(IV)/EDTA complex (molecular scissors). The scission site of ARCUT and its scission specificity can be freely modulated in terms of the sequences and lengths of the pcPNA strands so that even huge genomes can be selectively cut at only one predetermined site. In this chapter, the method of site-selective scission of human genomic DNA using ARCUT is described in detail.

  17. Cross-catalytic peptide nucleic acid (PNA) replication based on templated ligation

    DEFF Research Database (Denmark)

    Singhal, Abhishek; Nielsen, Peter E


    We report the first PNA self-replicating system based on template directed cross-catalytic ligation, a process analogous to biological replication. Using two template PNAs and four pentameric precursor PNAs, all four possible carbodiimide assisted amide ligation products were detected and identif......We report the first PNA self-replicating system based on template directed cross-catalytic ligation, a process analogous to biological replication. Using two template PNAs and four pentameric precursor PNAs, all four possible carbodiimide assisted amide ligation products were detected...... and identified by HPLC and MALDI-TOF analysis. We conclude that the two template complementary reaction products are generated via cross-catalysis, while the other two self-complementary (and in principle auto-catalytic) products are formed via intra-complex coupling between the two sets of complementary PNA...

  18. A high-efficiency aerothermoelastic analysis method (United States)

    Wan, ZhiQiang; Wang, YaoKun; Liu, YunZhen; Yang, Chao


    In this paper, a high-efficiency aerothermoelastic analysis method based on unified hypersonic lifting surface theory is established. The method adopts a two-way coupling form that couples the structure, aerodynamic force, and aerodynamic thermo and heat conduction. The aerodynamic force is first calculated based on unified hypersonic lifting surface theory, and then the Eckert reference temperature method is used to solve the temperature field, where the transient heat conduction is solved using Fourier's law, and the modal method is used for the aeroelastic correction. Finally, flutter is analyzed based on the p-k method. The aerothermoelastic behavior of a typical hypersonic low-aspect ratio wing is then analyzed, and the results indicate the following: (1) the combined effects of the aerodynamic load and thermal load both deform the wing, which would increase if the flexibility, size, and flight time of the hypersonic aircraft increase; (2) the effect of heat accumulation should be noted, and therefore, the trajectory parameters should be considered in the design of hypersonic flight vehicles to avoid hazardous conditions, such as flutter.

  19. Multi-petascale highly efficient parallel supercomputer (United States)

    Asaad, Sameh; Bellofatto, Ralph E.; Blocksome, Michael A.; Blumrich, Matthias A.; Boyle, Peter; Brunheroto, Jose R.; Chen, Dong; Cher, Chen -Yong; Chiu, George L.; Christ, Norman; Coteus, Paul W.; Davis, Kristan D.; Dozsa, Gabor J.; Eichenberger, Alexandre E.; Eisley, Noel A.; Ellavsky, Matthew R.; Evans, Kahn C.; Fleischer, Bruce M.; Fox, Thomas W.; Gara, Alan; Giampapa, Mark E.; Gooding, Thomas M.; Gschwind, Michael K.; Gunnels, John A.; Hall, Shawn A.; Haring, Rudolf A.; Heidelberger, Philip; Inglett, Todd A.; Knudson, Brant L.; Kopcsay, Gerard V.; Kumar, Sameer; Mamidala, Amith R.; Marcella, James A.; Megerian, Mark G.; Miller, Douglas R.; Miller, Samuel J.; Muff, Adam J.; Mundy, Michael B.; O'Brien, John K.; O'Brien, Kathryn M.; Ohmacht, Martin; Parker, Jeffrey J.; Poole, Ruth J.; Ratterman, Joseph D.; Salapura, Valentina; Satterfield, David L.; Senger, Robert M.; Smith, Brian; Steinmacher-Burow, Burkhard; Stockdell, William M.; Stunkel, Craig B.; Sugavanam, Krishnan; Sugawara, Yutaka; Takken, Todd E.; Trager, Barry M.; Van Oosten, James L.; Wait, Charles D.; Walkup, Robert E.; Watson, Alfred T.; Wisniewski, Robert W.; Wu, Peng


    A Multi-Petascale Highly Efficient Parallel Supercomputer of 100 petaOPS-scale computing, at decreased cost, power and footprint, and that allows for a maximum packaging density of processing nodes from an interconnect point of view. The Supercomputer exploits technological advances in VLSI that enables a computing model where many processors can be integrated into a single Application Specific Integrated Circuit (ASIC). Each ASIC computing node comprises a system-on-chip ASIC utilizing four or more processors integrated into one die, with each having full access to all system resources and enabling adaptive partitioning of the processors to functions such as compute or messaging I/O on an application by application basis, and preferably, enable adaptive partitioning of functions in accordance with various algorithmic phases within an application, or if I/O or other processors are underutilized, then can participate in computation or communication nodes are interconnected by a five dimensional torus network with DMA that optimally maximize the throughput of packet communications between nodes and minimize latency.

  20. High gain high efficiency resonant DC-DC converter (United States)

    Shang, Fei

    Low voltage power sources have played an important role in applications such as automotive system, renewable energy power generation and so on, where require a high gain DC-DC step-up converter. The converter is going to sustain a very high input current which can bring many design challenges in the existing topologies, such as high component current stress and power loss, complex and costly design for magnetic components, high input current ripple, etc. A new topology of high gain DCDC step-up converter proposed in this dissertation. The topology has many merits such as high gain capability, high efficiency, low components stress and requirement of the transformer, simple topology with less number of active switching devices, and easy to control. The dissertation carries out theoretical analysis of the proposed topology under different operating modes and the voltage gain has been deduced for each mode. The design of circuit components has been well studied, including the power devices current stress and power, the selection of transformer turns-ratio, the design method of the resonant tank and input current ripple. System dynamic state-space models are acquired by using generalized averaging method. Small signal model of the converter is achieved by linearization of the dynamic model around the operating points. The stability study indicates that the open loop system is stable at all operating points, except some operating points containing RHP zeros which can cause closed loop system unstable. The parameter sensitivity study shows that the system transfer function is not greatly affected by the variation of the leakage inductance and load resistance. A design of PI controller is implemented to achieve the output voltage regulation. Simulations have been carried out to validate the circuit operation and support the design analysis. A 2kW prototype has been built for experimental testing. The experimental results are in a good agreement with the theoretical

  1. Highly efficient silicon light emitting diode

    NARCIS (Netherlands)

    Le Minh, P.; Holleman, J.; Wallinga, Hans


    In this paper, we describe the fabrication, using standard silicon processing techniques, of silicon light-emitting diodes (LED) that efficiently emit photons with energy around the silicon bandgap. The improved efficiency had been explained by the spatial confinement of charge carriers due to a

  2. Towards high efficiency segmented thermoelectric unicouples

    DEFF Research Database (Denmark)

    Pham, Hoang Ngan; Christensen, Dennis Valbjørn; Snyder, Gerald Jeffrey


    of the theoretical efficiency of the best performing unicouples designed from segmenting the state-of-the-art TE materials. The efficiencies are evaluated using a 1D numerical model which includes all thermoelectric effects, heat conduction, Joule effects and temperature dependent material properties, but neglects...

  3. Rapid detection of urinary tract infections caused by Proteus spp. using PNA-FISH. (United States)

    Almeida, C; Azevedo, N F; Bento, J C; Cerca, N; Ramos, H; Vieira, M J; Keevil, C W


    We developed a fluorescence in situ hybridization (FISH) method for the rapid detection of Proteus spp. in urine, using a novel peptide nucleic acid (PNA) probe. Testing on 137 urine samples from patients with urinary tract infections has shown specificity and sensitivity values of 98 % (95 % CI, 93.2-99.7) and 100 % (95 % CI, 80,8-100), respectively, when compared with CHROMagar Orientation medium. Results indicate that PNA-FISH is a reliable alternative to traditional culture methods and can reduce the diagnosis time to approximately 2 h.

  4. Peptide nucleic acid (PNA) cell penetrating peptide (CPP) conjugates as carriers for cellular delivery of antisense oligomers

    DEFF Research Database (Denmark)

    Shiraishi, Takehiko; Nielsen, Peter E


    We have explored the merits of a novel delivery strategy for the antisense oligomers based on cell penetrating peptide (CPP) conjugated to a carrier PNA with sequence complementary to part of the antisense oligomer. The effect of these carrier CPP-PNAs was evaluated by using antisense PNA targeti...

  5. Subnanomolar antisense activity of phosphonate-peptide nucleic acid (PNA) conjugates delivered by cationic lipids to HeLa cells

    DEFF Research Database (Denmark)

    Shiraishi, Takehiko; Hamzavi, Ramin; Nielsen, Peter E


    oligomer. This modification of the PNA does not interfere with the nucleic acid target binding affinity based on thermal stability of the PNA/RNA duplexes. When delivered to cultured HeLa pLuc705 cells by Lipofectamine, the PNAs showed dose-dependent nuclear antisense activity in the nanomolar range...

  6. Neutron scintillators with high detection efficiency

    Energy Technology Data Exchange (ETDEWEB)

    Kojima, T.; Katagiri, M. E-mail:; Tsutsui, N.; Imai, K.; Matsubayashi, M.; Sakasai, K


    We have developed three kinds of phosphor/neutron-converter scintillators aiming to increase the detection efficiency of the neutron imaging detectors. One is the ZnS:Ag/{sup 6}LiF (powder) scintillator, which contained {sup 6}LiF about twice in amount comparing to the commercial product (Bicron, BC-704) and painted in a sheet, and the 0.4-mm-thick scintillator sheet exhibited the detection efficiency of 43.5% for thermal neutrons. This value was improved {approx}1.5 times than that of BC-704. Another developed scintillator was a ZnS:Ag/{sup 10}B{sub 2}O{sub 3} (powder), which contained {sup 10}B as a neutron converter. The scintillator was fabricated by sintering up to the temperature of 500 or 600 deg. C, and it exhibited the detection efficiency of 30% for thermal neutrons. Moreover, we developed ZnS:Ag/{sup 10}B{sub 2}O{sub 3} glass-scintillator, which was fabricated by increasing the amount of {sup 10}B{sub 2}O{sub 3} up to 70-90% of the constituents and by sintering the scintillator materials up to the temperature of 650 deg. C. The fabricated glass scintillators, which had a thickness of 0.9-1 mm, exhibited the detection efficiency of 20-40% for thermal neutrons.

  7. Designing high efficient solar powered lighting systems

    DEFF Research Database (Denmark)

    Poulsen, Peter Behrensdorff; Thorsteinsson, Sune; Lindén, Johannes


    -Port-Converters respectively for 1-10Wp and 10-50 Wp with a peak efficiency of 97% at 1.8 W of PV power for the 10 Wp version. Furthermore, a modelling tool for L2L products has been developed and a laboratory for feeding in component data not available in the datasheets to the model is described....

  8. Designing high efficient solar powered lighting systems

    DEFF Research Database (Denmark)

    Poulsen, Peter Behrensdorff; Thorsteinsson, Sune; Lindén, Johannes

    -Port-Converters respectively for 1-10Wp and 10-50 Wp with a peak efficiency of 97% at 1.8 W of PV power for the 10 Wp version. Furthermore, a modelling tool for L2L products has been developed and a laboratory for feeding in component data not available in the datasheets to the model is described....

  9. Cross-catalytic peptide nucleic acid (PNA) replication based on templated ligation

    DEFF Research Database (Denmark)

    Singhal, Abhishek; Nielsen, Peter E


    and identified by HPLC and MALDI-TOF analysis. We conclude that the two template complementary reaction products are generated via cross-catalysis, while the other two self-complementary (and in principle auto-catalytic) products are formed via intra-complex coupling between the two sets of complementary PNA...

  10. Targeted gene correction using psoralen, chlorambucil and camptothecin conjugates of triplex forming peptide nucleic acid (PNA)

    DEFF Research Database (Denmark)

    Birkedal, Henrik; Nielsen, Peter E


    Gene correction activation effects of a small series of triplex forming peptide nucleic acid (PNA) covalently conjugated to the DNA interacting ligands psoralen, chlorambucil and camptothecin targeted proximal to a stop codon mutation in an EGFP reporter gene were studied. A 15-mer homopyrimidine...

  11. Energy efficiency indicators for high electric-load buildings

    Energy Technology Data Exchange (ETDEWEB)

    Aebischer, Bernard; Balmer, Markus A.; Kinney, Satkartar; Le Strat, Pascale; Shibata, Yoshiaki; Varone, Frederic


    Energy per unit of floor area is not an adequate indicator for energy efficiency in high electric-load buildings. For two activities, restaurants and computer centres, alternative indicators for energy efficiency are discussed.

  12. Efficient and Highly Aldehyde Selective Wacker Oxidation

    KAUST Repository

    Teo, Peili


    A method for efficient and aldehyde-selective Wacker oxidation of aryl-substituted olefins using PdCl 2(MeCN) 2, 1,4-benzoquinone, and t-BuOH in air is described. Up to a 96% yield of aldehyde can be obtained, and up to 99% selectivity can be achieved with styrene-related substrates. © 2012 American Chemical Society.

  13. High Thrust Efficiency MPD Thruster Project (United States)

    National Aeronautics and Space Administration — Magnetoplasmadynamic (MPD) thrusters can provide the high-specific impulse, high-power propulsion required to support human and robotic exploration missions to the...

  14. Efficiency of cellular delivery of antisense peptide nucleic acid by electroporation depends on charge and electroporation geometry

    DEFF Research Database (Denmark)

    Joergensen, Mette; Agerholm-Larsen, Birgit; Nielsen, Peter E


    with a functional luciferase readout, we demonstrate that parameters such as peptide nucleic acid (PNA) charge and the method of electroporation have dramatic influence on the efficiency of productive delivery. In a suspended cell electroporation system (cuvettes), a positively charged PNA (+8) was most efficiently...... transferred, whereas charge neutral PNA was more effective in a microtiter plate electrotransfer system for monolayer cells. Surprisingly, a negatively charged (-23) PNA did not show appreciable activity in either system. Findings from the functional assay were corroborated by pulse parameter variations......, polymerase chain reaction, and confocal microscopy. In conclusion, we have found that the charge of PNA and electroporation system combination greatly influences the transfer efficiency, thereby illustrating the complexity of the electroporation mechanism....

  15. High Efficiency Thermoelectric Radioisotope Power Systems (United States)

    El-Genk, Mohamed; Saber, Hamed; Caillat, Thierry


    The work performed and whose results presented in this report is a joint effort between the University of New Mexico s Institute for Space and Nuclear Power Studies (ISNPS) and the Jet Propulsion Laboratory (JPL), California Institute of Technology. In addition to the development, design, and fabrication of skutterudites and skutterudites-based segmented unicouples this effort included conducting performance tests of these unicouples for hundreds of hours to verify theoretical predictions of the conversion efficiency. The performance predictions of these unicouples are obtained using 1-D and 3-D models developed for that purpose and for estimating the actual performance and side heat losses in the tests conducted at ISNPS. In addition to the performance tests, the development of the 1-D and 3-D models and the development of Advanced Radioisotope Power systems for Beginning-Of-Life (BOM) power of 108 We are carried out at ISNPS. The materials synthesis and fabrication of the unicouples are carried out at JPL. The research conducted at ISNPS is documented in chapters 2-5 and that conducted at JP, in documented in chapter 5. An important consideration in the design and optimization of segmented thermoelectric unicouples (STUs) is determining the relative lengths, cross-section areas, and the interfacial temperatures of the segments of the different materials in the n- and p-legs. These variables are determined using a genetic algorithm (GA) in conjunction with one-dimensional analytical model of STUs that is developed in chapter 2. Results indicated that when optimized for maximum conversion efficiency, the interfacial temperatures between various segments in a STU are close to those at the intersections of the Figure-Of-Merit (FOM), ZT, curves of the thermoelectric materials of the adjacent segments. When optimizing the STUs for maximum electrical power density, however, the interfacial temperatures are different from those at the intersections of the ZT curves, but

  16. High-Efficient Circuits for Ternary Addition

    Directory of Open Access Journals (Sweden)

    Reza Faghih Mirzaee


    Full Text Available New ternary adders, which are fundamental components of ternary addition, are presented in this paper. They are on the basis of a logic style which mostly generates binary signals. Therefore, static power dissipation reaches its minimum extent. Extensive different analyses are carried out to examine how efficient the new designs are. For instance, the ternary ripple adder constructed by the proposed ternary half and full adders consumes 2.33 μW less power than the one implemented by the previous adder cells. It is almost twice faster as well. Due to their unique superior characteristics for ternary circuitry, carbon nanotube field-effect transistors are used to form the novel circuits, which are entirely suitable for practical applications.

  17. Design High Efficiency PWM Boost Converter for Wind Power Generation

    National Research Council Canada - National Science Library



    ...; it is offer high efficiency performance andprovides power management circuit designers with theability to approach a broad range of designapplications with flexible and easy-to-implementsolutions...

  18. Role of SbmA in the Uptake of Peptide Nucleic Acid (PNA)-Peptide Conjugates in E. coli

    DEFF Research Database (Denmark)

    Ghosal, Anubrata; Vitali, Ally; Stach, James E M


    Antisense PNA oligomers targeting essential genes (acpP or ftsZ) and conjugated to the delivery peptide L((KFF)(3)K) show complete growth inhibition of wild type E. coli strain (MG1655) with submicromolar MIC. In this study we show that resistant mutants generated against such PNA......-peptide conjugates had disruptions in the region of sbmA, a gene encoding an inner membrane peptide transporter. The wild type sensitivity to the PNA conjugates was re-established in the resistance mutants by complementation with sbmA. Furthermore, deletion of sbmA in E. coli AS19, a strain that is sensitive...

  19. Rapid identification of bacteria and candida using pna-fish from blood and peritoneal fluid cultures: a retrospective clinical study

    Directory of Open Access Journals (Sweden)

    Harris Dana M


    Full Text Available Abstract Background Peptide nucleic acid fluorescent in situ hybridization (PNA-FISH is a rapid and established method for identification of Candida sp., Gram positive, and Gram negative bacteria from positive blood cultures. This study reports clinical experience in the evaluation of 103 positive blood cultures and 17 positive peritoneal fluid cultures from 120 patients using PNA-FISH. Our study provides evidence as to potential pharmaceutical cost savings based on rapid pathogen identification, in addition to the novel application of PNA-FISH to peritoneal fluid specimens. Methods Identification accuracy and elapsed time to identification of Gram positives, Gram negatives, and Candida sp., isolated from blood and peritoneal fluid cultures were assessed using PNA-FISH (AdvanDx, as compared to standard culture methods. Patient charts were reviewed to extrapolate potential pharmaceutical cost savings due to adjustment of antimicrobial or antifungal therapy, based on identification by PNA-FISH. Results In blood cultures, time to identification by standard culture methods for bacteria and Candida sp., averaged 83.6 hours (95% CI 56.7 to 110.5. Identification by PNA-FISH averaged 11.2 hours (95% CI 4.8 to 17.6. Overall PNA-FISH identification accuracy was 98.8% (83/84, 95% CI 93.5% to 99.9% as compared to culture. In peritoneal fluid, identification of bacteria by culture averaged 87.4 hours (95% CI −92.4 to 267.1. Identification by PNA-FISH averaged 16.4 hours (95% CI −57.3 to 90.0. Overall PNA-FISH identification accuracy was 100% (13/13, 95% CI 75.3% to 100%. For Candida sp., pharmaceutical cost savings based on PNA-FISH identification could be $377.74/day. For coagulase-negative staphylococcus (CoNS, discontinuation of vancomycin could result in savings of $20.00/day. Conclusions In this retrospective study, excellent accuracy of PNA-FISH in blood and peritoneal fluids with reduced time to identification was observed, as compared to

  20. High Efficiency Regenerative Helium Compressor Project (United States)

    National Aeronautics and Space Administration — Helium plays several critical rolls in spacecraft propulsion. High pressure helium is commonly used to pressurize propellant fuel tanks. Helium cryocoolers can be...

  1. High-efficiency airfoil rudders applied to submarines

    Directory of Open Access Journals (Sweden)

    ZHOU Yimei


    Full Text Available Modern submarine design puts forward higher and higher requirements for control surfaces, and this creates a requirement for designers to constantly innovate new types of rudder so as to improve the efficiency of control surfaces. Adopting the high-efficiency airfoil rudder is one of the most effective measures for improving the efficiency of control surfaces. In this paper, we put forward an optimization method for a high-efficiency airfoil rudder on the basis of a comparative analysis of the various strengths and weaknesses of the airfoil, and the numerical calculation method is adopted to analyze the influence rule of the hydrodynamic characteristics and wake field by using the high-efficiency airfoil rudder and the conventional NACA rudder comparatively; at the same time, a model load test in a towing tank was carried out, and the test results and simulation calculation obtained good consistency:the error between them was less than 10%. The experimental results show that the steerage of a high-efficiency airfoil rudder is increased by more than 40% when compared with the conventional rudder, but the total resistance is close:the error is no more than 4%. Adopting a high-efficiency airfoil rudder brings much greater lifting efficiency than the total resistance of the boat. The results show that high-efficiency airfoil rudder has obvious advantages for improving the efficiency of control, giving it good application prospects.

  2. Preparation of highly efficient manganese catalase mimics. (United States)

    Triller, Michael U; Hsieh, Wen-Yuan; Pecoraro, Vincent L; Rompel, Annette; Krebs, Bernt


    The series of compounds [Mn(bpia)(mu-OAc)](2)(ClO(4))(2) (1), [Mn(2)(bpia)(2)(muO)(mu-OAc)](ClO(4))(3).CH(3)CN (2), [Mn(bpia)(mu-O)](2)(ClO(4))(2)(PF(6)).2CH(3)CN (3), [Mn(bpia)(Cl)(2)](ClO)(4) (4), and [(Mn(bpia)(Cl))(2)(mu-O)](ClO(4))(2).2CH(3)CN (5) (bpia = bis(picolyl)(N-methylimidazol-2-yl)amine) represents a structural, spectroscopic, and functional model system for manganese catalases. Compounds 3 and 5 have been synthesized from 2 via bulk electrolysis and ligand exchange, respectively. All complexes have been structurally characterized by X-ray crystallography and by UV-vis and EPR spectroscopies. The different bridging ligands including the rare mono-mu-oxo and mono-mu-oxo-mono-mu-carboxylato motifs lead to a variation of the Mn-Mn separation across the four binuclear compounds of 1.50 A (Mn(2)(II,II) = 4.128 A, Mn(2)(III,III) = 3.5326 and 3.2533 A, Mn(2)(III,IV) = 2.624 A). Complexes 1, 2, and 3 are mimics for the Mn(2)(II,II), the Mn(2)(III,III), and the Mn(2)(III,IV) oxidation states of the native enzyme. UV-vis spectra of these compounds show similarities to those of the corresponding oxidation states of manganese catalase from Thermus thermophilus and Lactobacillus plantarum. Compound 2 exhibits a rare example of a Jahn-Teller compression. While complexes 1 and 3 are efficient catalysts for the disproportionation of hydrogen peroxide and contain an N(4)O(2) donor set, 4 and 5 show no catalase activity. These complexes have an N(4)Cl(2) and N(4)OCl donor set, respectively, and serve as mimics for halide inhibited manganese catalases. Cyclovoltammetric data show that the substitution of oxygen donor atoms with chloride causes a shift of redox potentials to more positive values. To our knowledge, complex 1 is the most efficient binuclear functional manganese catalase mimic exhibiting saturation kinetics to date.

  3. Energy Efficient and Compact RF High-Power Amplifiers

    NARCIS (Netherlands)

    Calvillo Cortés, D.A.


    The main objectives of this thesis are to improve the energy efficiency and physical form-factor of high-power amplifiers in base station applications. As such, the focus of this dissertation is placed on the outphasing amplifier concept, which can offer high-efficiency, good linearity and excellent

  4. High efficiency low cost GaAs/Ge cell technology (United States)

    Ho, Frank


    Viewgraphs on high efficiency low cost GaAs/Ge cell technology are presented. Topics covered include: high efficiency, low cost GaAs/Ge solar cells; advantages of Ge; comparison of typical production cells for space applications; panel level comparisons; and solar cell technology trends.

  5. Investigation of High Efficiency Generalized Matched Filters. (United States)


    the Fourier spectrum of the object itself. Lohmann and Thum show that a constant amplitude photographic il.:L made with an object and mask yields high...Fourier transform which is, of course, uniphase ( positive ). We used the simplest triangle for b(x), i.e. 1 Figure 5. In two dimensions, 0 1/2 0 b...backgrounds are desirable in order that 1) Coordinates of correlation peaks can be positively identified and 2) Background random noise spectra are excluded

  6. Efficient production of high-rise buildings


    Hoseini, Hanif


    Production of one family houses has over time developed successfully in Sweden and producers have managed to reduce the production costs and industrialize the production process. The development has however not been that successful when it comes to high-rise buildings. There are many attempts made, but no one has really managed to create a product that can persuade the market. The systems used are not flexible and cannot cope very well with variations in the design. The aim of this work has b...

  7. The influence of a chiral amino acid on the helical handedness of PNA in solution and in crystals

    DEFF Research Database (Denmark)

    Rasmussen, Hanne B.; Petersson, B; Nielsen, P E


    The X-ray structure of a self-complementary PNA hexamer (H-CGTACG-L-Lys-NH(2)) has been determined to 2.35 A resolution. The introduction of an L-lysine moiety has previously been shown to induce a preferred left-handedness of the PNA double helices in aqueous solution. However, in the crystal...... structure an equal amount of interchanging right- and left-handed helices is observed. The lysine moieties are pointing into large solvent channels and no significant interactions between this moiety and the remaining PNA molecule are observed. In contrast, molecular mechanics calculations show a preference...... for the left-handed helix of this hexameric PNA in aqueous solution as expected. The calculations indicate that the difference in the free energy of solvation between the left-handed and the right-handed helix is the determining factor for the preference of the left-handed helix in aqueous solution....

  8. Effect of temperature and ionic strength on the dissociation kinetics and lifetime of PNA-DNA triplexes

    DEFF Research Database (Denmark)

    Kosaganov, Y N; Stetsenko, D A; Lubyako, E N


    (10) PNA complexes with ss- and dsDNA were equal within the accuracy of experiments. The activation energy, U, value for T(10) PNA-DNA complexes did not change when the NaCl concentration was increased from 50 to 200 or 600 mM. Conversely, the tau values decreased with the increase in Na......Dissociation kinetics of triplexes formed by molecules of peptide nucleic acid (PNA) and DNA have been studied. The complexes consisted of oligomeric PNA containing 10 thymine bases and the dA(10) target incorporated in single-stranded (ssDNA) or double-stranded DNA (dsDNA). Their dissociation...... was followed by means of the gel mobility shift assay at various temperatures and sodium ion concentrations. In all experiments, the dissociation kinetics of triplexes were exponential; the effective lifetime of a triplex, tau, depended on temperature in accordance with the Arrhenius law. The tau values for T...

  9. Surface density dependence of PCR amplicon hybridization on PNA/DNA probe layers

    DEFF Research Database (Denmark)

    Yao, Danfeng; Kim, Junyoung; Yu, Fang


    at an intermediate sodium concentration (approximately 100 mM). These effects were mainly ascribed to the electrostatic cross talk among the hybridized DNA molecules and the secondary structure of PCR amplicons. For the negatively charged DNA probes, the hybridization reaction was subjected additionally to the DNA...... biotin/streptavidin interaction. Despite the neutral backbone of PNA, the hybridization reactions were strongly influenced by the variation of ionic strength. The association rates exhibited a monotonic decrease with ionic strength increase and the maximum hybridization signal was achieved......Surface plasmon field-enhanced fluorescence spectroscopy was employed to extensively investigate the hybridization behaviors of polymerase chain reaction (PCR) amplicons on a peptide nucleic acid (PNA) or DNA probe layer that was previously attached on a streptavidin-modified gold surface via...

  10. All passive architecture for high efficiency cascaded Raman conversion (United States)

    Balaswamy, V.; Arun, S.; Chayran, G.; Supradeepa, V. R.


    Cascaded Raman fiber lasers have offered a convenient method to obtain scalable, high-power sources at various wavelength regions inaccessible with rare-earth doped fiber lasers. A limitation previously was the reduced efficiency of these lasers. Recently, new architectures have been proposed to enhance efficiency, but this came at the cost of enhanced complexity, requiring an additional low-power, cascaded Raman laser. In this work, we overcome this with a new, all-passive architecture for high-efficiency cascaded Raman conversion. We demonstrate our architecture with a fifth-order cascaded Raman converter from 1117nm to 1480nm with output power of ~64W and efficiency of 60%.

  11. A novel pseudo-complementary PNA G-C base pair

    DEFF Research Database (Denmark)

    Olsen, Anne G.; Dahl, Otto; Petersen, Asger Bjørn


    Pseudo-complementary oligonucleotide analogues and mimics provide novel opportunities for targeting duplex structures in RNA and DNA. Previously, a pseudo-complementary A-T base pair has been introduced. Towards sequence unrestricted targeting, a pseudo-complementary G-C base pair consisting...... of the unnatural nucleobases n6-methoxy-2,6-diaminopurine (previously described in a DNA context) and N4-benzoylcytosine is now presented for design of pseudo-complementary PNA oligomers (pcPNAs)....

  12. Crystal structure of a partly self-complementary peptide nucleic acid (PNA) oligomer showing a duplex-triplex network

    DEFF Research Database (Denmark)

    Petersson, Britt; Nielsen, Bettina Bryde; Rasmussen, Hanne


    of the decamer (G(4)A(5)T(6)C(7)). One right- and one left-handed Watson-Crick duplex are formed. The two PNA units C(9)T(10) change helical handedness, so that each PNA strand contains both a right- and a left-handed section. The changed handedness in C(9)T(10) allows formation of Hoogsteen hydrogen bonding...... Hoogsteen type. The structural diversity of this PNA demonstrates how the PNA backbone is able to adapt to structures governed by the stacking and hydrogen-bonding interactions between the nucleobases. The crystal structure further shows how PNA oligomers containing limited sequence complementarity may form......The X-ray structure of a partly self-complementary peptide nucleic acid (PNA) decamer (H-GTAGATCACT-l-Lys-NH(2)) to 2.60 A resolution is reported. The structure is mainly controlled by the canonical Watson-Crick base pairs formed by the self-complementary stretch of four bases in the middle...

  13. High efficiency endocrine operation protocol: From design to implementation. (United States)

    Mascarella, Marco A; Lahrichi, Nadia; Cloutier, Fabienne; Kleiman, Simcha; Payne, Richard J; Rosenberg, Lawrence


    We developed a high efficiency endocrine operative protocol based on a mathematical programming approach, process reengineering, and value-stream mapping to increase the number of operations completed per day without increasing operating room time at a tertiary-care, academic center. Using this protocol, a case-control study of 72 patients undergoing endocrine operation during high efficiency days were age, sex, and procedure-matched to 72 patients undergoing operation during standard days. The demographic profile, operative times, and perioperative complications were noted. The average number of cases per 8-hour workday in the high efficiency and standard operating rooms were 7 and 5, respectively. Mean procedure times in both groups were similar. The turnaround time (mean ± standard deviation) in the high efficiency group was 8.5 (±2.7) minutes as compared with 15.4 (±4.9) minutes in the standard group (P < .001). Transient postoperative hypocalcemia was 6.9% (5/72) and 8.3% (6/72) for the high efficiency and standard groups, respectively (P = .99). In this study, patients undergoing high efficiency endocrine operation had similar procedure times and perioperative complications compared with the standard group. The proposed high efficiency protocol seems to better utilize operative time and decrease the backlog of patients waiting for endocrine operation in a country with a universal national health care program. Copyright © 2016 Elsevier Inc. All rights reserved.

  14. The Energy Efficiency of High Intensity Proton Driver Concepts

    Energy Technology Data Exchange (ETDEWEB)

    Yakovlev, Vyacheslav [Fermilab; Grillenberger, Joachim [PSI, Villigen; Kim, Sang-Ho [ORNL, Oak Ridge (main); Seidel, Mike [PSI, Villigen; Yoshii, Masahito [JAEA, Ibaraki


    For MW class proton driver accelerators the energy efficiency is an important aspect; the talk reviews the efficiency of different accelerator concepts including s.c./n.c. linac, rapid cycling synchrotron, cyclotron; the potential of these concepts for very high beam power is discussed.

  15. MACRIB High efficiency - high purity hadron identification for DELPHI

    CERN Document Server

    Albrecht, Z; Moch, M; Albrecht, Zoltan; Feindt, Michael; Moch, Markus


    Analysis of the data shows that hadron tags of the two standard DELPHI particle identification packages RIBMEAN and HADSIGN are weakly correlated. This led to the idea of constructing a neural network for both kaon and proton identification using as input the existing tags from RIBMEAN and HADSIGN, as well as preproccessed TPC and RICH detector measurements together with additional dE/dx information from the DELPHI vertex detector. It will be shown in this note that the net output is much more efficient at the same purity than the HADSIGN or RIBMEAN tags alone. We present an easy-to-use routine performing the necessary calculations.

  16. Highly efficient resistive plate chambers for high rate environment

    CERN Document Server

    Cwiok, M; Górski, M; Królikowski, J


    The full scale prototype of an inverted double gap RPC module for ME-1/1 station of the CMS detector was tested in the gamma irradiation facility at the CERN SPS muon beam. The chamber made of medium resistivity bakelite and filled with "green gas" mixture of C /sub 2/H/sub 2/F/sub 4//iso-butane/SF/sub 6/ has wide efficiency plateau and good timing properties when operated in avalanche mode under continuous irradiation with strong /sup 137/Cs source for rates up to about 5 kHz/cm/sup 2//gap. (10 refs).

  17. Compact Tunable High-Efficiency Entangled Photon Source Project (United States)

    National Aeronautics and Space Administration — MagiQ proposes to develop a compact tunable high-efficiency low-power-consumption entangled photon source. The source, based on inter-Fabry-Perot-cavity Spontaneous...

  18. An Improved, Highly Efficient Method for the Synthesis of Bisphenols

    Directory of Open Access Journals (Sweden)

    L. S. Patil


    Full Text Available An efficient synthesis of bisphenols is described by condensation of substituted phenols with corresponding cyclic ketones in presence of cetyltrimethylammonium chloride and 3-mercaptopropionic acid as a catalyst in extremely high purity and yields.

  19. High Efficiency Lighting with Integrated Adaptive Control (HELIAC) Project (United States)

    National Aeronautics and Space Administration — The proposed project is the continued development of the High Efficiency Lighting with Integrated Adaptive Control (HELIAC) system. Solar radiation is not a viable...

  20. High Efficiency Lighting with Integrated Adaptive Control (HELIAC) Project (United States)

    National Aeronautics and Space Administration — The innovation of the proposed project is the development of High Efficiency Lighting with Integrated Adaptive Control (HELIAC) systems to drive plant growth. Solar...

  1. Highly Efficient Solid Oxide Electrolyzer & Sabatier System Project (United States)

    National Aeronautics and Space Administration — Paragon Space Development Corporation® (Paragon) and ENrG Incorporated (ENrG) are teaming to provide a highly efficient reactor for carbon monoxide/carbon...

  2. Highly Efficient Solid Oxide Electrolyzer & Sabatier System Project (United States)

    National Aeronautics and Space Administration — Paragon Space Development Corporation (Paragon) and ENrG Incorporated (ENrG) are teaming to provide a highly efficient reactor for carbon monoxide/carbon dioxide...

  3. High Efficiency Direct Methane Solid Oxide Fuel Cell System Project (United States)

    National Aeronautics and Space Administration — NASA has a defined need for energy dense and highly efficient energy storage and power delivery systems for future space missions. Compared to other fuel cell...

  4. Highly efficient procedure for the transesterification of vegetable oil

    Energy Technology Data Exchange (ETDEWEB)

    Liang, Xuezheng; Gao, Shan; He, Mingyuan [Shanghai Key Laboratory of Green Chemistry and Chemical Process, Department of Chemistry, East China Normal University, Shanghai 200062 (China); Yang, Jianguo [Shanghai Key Laboratory of Green Chemistry and Chemical Process, Department of Chemistry, East China Normal University, Shanghai 200062 (China); Energy Institute, Department of Materials Science and Engineering, Pennsylvania State University, University Park, PA 16802 (United States)


    The highly efficient procedure has been developed for the synthesis of biodiesel from vegetable oil and methanol. The KF/MgO has been selected as the most efficient catalyst for the reactions with the yield of 99.3%. Operational simplicity, without need of the purification of raw vegetable oil, low cost of the catalyst used, high activities, no saponification and reusability are the key features of this methodology. (author)

  5. Highly-Efficient and Modular Medium-Voltage Converters (United States)


    of the modular multilevel converter based on si and sic switching devices for medium/high-voltage applications," IEEE Trans. Electron Devices, vol...4. TITLE AND SUBTITLE Highly-Efficient and Modula Medium-Voltage Converters 6. AUTHOR(S) Maryam Saeedifard 7. PERFORMING ORGANIZATIC i NAME(S...improving the converter’s efficiency and power density. 15. SUBJECT TERMS Modular Multilevel Converters , DC-DC Conversion, DC-AC Conversion 16

  6. The photonic nanowire: A highly efficient single-photon source

    DEFF Research Database (Denmark)

    Gregersen, Niels


    The photonic nanowire represents an attractive platform for a quantum light emitter. However, careful optical engineering using the modal method, which elegantly allows access to all relevant physical parameters, is crucial to ensure high efficiency.......The photonic nanowire represents an attractive platform for a quantum light emitter. However, careful optical engineering using the modal method, which elegantly allows access to all relevant physical parameters, is crucial to ensure high efficiency....

  7. Global climate change: Mitigation opportunities high efficiency large chiller technology

    Energy Technology Data Exchange (ETDEWEB)

    Stanga, M.V.


    This paper, comprised of presentation viewgraphs, examines the impact of high efficiency large chiller technology on world electricity consumption and carbon dioxide emissions. Background data are summarized, and sample calculations are presented. Calculations show that presently available high energy efficiency chiller technology has the ability to substantially reduce energy consumption from large chillers. If this technology is widely implemented on a global basis, it could reduce carbon dioxide emissions by 65 million tons by 2010.

  8. Enzymatic Reaction with Unnatural Substrates: DNA Photolyase (Escherichia coli) Recognizes and Reverses Thymine [2+2] Dimers in the DNA Strand of a DNA/PNA Hybrid Duplex (United States)

    Ramaiah, Danaboyina; Kan, Yongzhi; Koch, Troels; Orum, Henrik; Schuster, Gary B.


    Peptide nucleic acids (PNA) are mimics with normal bases connected to a pseudopeptide chain that obey Watson--Crick rules to form stable duplexes with itself and natural nucleic acids. This has focused attention on PNA as therapeutic or diagnostic reagents. Duplexes formed with PNA mirror some but not all properties of DNA. One fascinating aspect of PNA biochemistry is their reaction with enzymes. Here we show an enzyme reaction that operates effectively on a PNA/DNA hybrid duplex. A DNA oligonucleotide containing a cis, syn-thymine [2+2] dimer forms a stable duplex with PNA. The hybrid duplex is recognized by photolyase, and irradiation of the complex leads to the repair of the thymine dimer. This finding provides insight into the enzyme mechanism and provides a means for the selective repair of thymine photodimers.

  9. High efficiency USC power plant - present status and future potential

    Energy Technology Data Exchange (ETDEWEB)

    Blum, R. [Faelleskemikerne I/S Fynsvaerket (Denmark); Hald, J. [Elsam/Elkraft/TU Denmark (Denmark)


    Increasing demand for energy production with low impact on the environment and minimised fuel consumption can be met with high efficient coal fired power plants with advanced steam parameters. An important key to this improvement is the development of high temperature materials with optimised mechanical strength. Based on the results of more than ten years of development a coal fired power plant with an efficiency above 50 % can now be realised. Future developments focus on materials which enable an efficiency of 52-55 %. (orig.) 25 refs.

  10. Production technology for high efficiency ion implanted solar cells (United States)

    Kirkpatrick, A. R.; Minnucci, J. A.; Greenwald, A. C.; Josephs, R. H.


    Ion implantation is being developed for high volume automated production of silicon solar cells. An implanter designed for solar cell processing and able to properly implant up to 300 4-inch wafers per hour is now operational. A machine to implant 180 sq m/hr of solar cell material has been designed. Implanted silicon solar cells with efficiencies exceeding 16% AM1 are now being produced and higher efficiencies are expected. Ion implantation and transient processing by pulsed electron beams are being integrated with electrostatic bonding to accomplish a simple method for large scale, low cost production of high efficiency solar cell arrays.

  11. Efficient estimation for high similarities using odd sketches

    DEFF Research Database (Denmark)

    Mitzenmacher, Michael; Pagh, Rasmus; Pham, Ninh Dang


    . This means that Odd Sketches provide a highly space-efficient estimator for sets of high similarity, which is relevant in applications such as web duplicate detection, collaborative filtering, and association rule learning. The method extends to weighted Jaccard similarity, relevant e.g. for TF-IDF vector...... comparison. We present a theoretical analysis of the quality of estimation to guarantee the reliability of Odd Sketch-based estimators. Our experiments confirm this efficiency, and demonstrate the efficiency of Odd Sketches in comparison with $b$-bit minwise hashing schemes on association rule learning...

  12. Very-High Efficiency, High Power Laser Diodes Project (United States)

    National Aeronautics and Space Administration — AdTech Photonics, in collaboration with the Center for Advanced Studies in Photonics Research (CASPR) at UMBC, is pleased to submit this proposal entitled ?Very-High...

  13. High surface area electrode for high efficient microbial electrosynthesis (United States)

    Nie, Huarong; Cui, Mengmeng; Lu, Haiyun; Zhang, Tian; Russell, Thomas; Lovley, Derek


    Microbial electrosynthesis, a process in which microorganisms directly accept electrons from an electrode to convert carbon dioxide and water into multi carbon organic compounds, affords a novel route for the generation of valuable products from electricity or even wastewater. The surface area of the electrode is critical for high production. A biocompatible, highly conductive, three-dimensional cathode was fabricated from a carbon nanotube textile composite to support the microorganism to produce acetate from carbon dioxide. The high surface area and macroscale porous structure of the intertwined CNT coated textile ?bers provides easy microbe access. The production of acetate using this cathode is 5 fold larger than that using a planar graphite electrode with the same volume. Nickel-nanowire-modified carbon electrodes, fabricated by microwave welding, increased the surface area greatly, were able to absorb more bacteria and showed a 1.5 fold increase in performance

  14. Systematic Approach for Design of Broadband, High Efficiency, High Power RF Amplifiers

    National Research Council Canada - National Science Library

    Mohadeskasaei, Seyed Alireza; An, Jianwei; Chen, Yueyun; Li, Zhi; Abdullahi, Sani Umar; Sun, Tie


    ...‐AB RF amplifiers with high gain flatness. It is usually difficult to simultaneously achieve a high gain flatness and high efficiency in a broadband RF power amplifier, especially in a high power design...

  15. Development of high-efficiency solar cells on silicon web (United States)

    Meier, D. L.; Greggi, J.; Okeeffe, T. W.; Rai-Choudhury, P.


    Work was performed to improve web base material with a goal of obtaining solar cell efficiencies in excess of 18% (AM1). Efforts in this program are directed toward identifying carrier loss mechanisms in web silicon, eliminating or reducing these mechanisms, designing a high efficiency cell structure with the aid of numerical models, and fabricating high efficiency web solar cells. Fabrication techniques must preserve or enhance carrier lifetime in the bulk of the cell and minimize recombination of carriers at the external surfaces. Three completed cells were viewed by cross-sectional transmission electron microscopy (TEM) in order to investigate further the relation between structural defects and electrical performance of web cells. Consistent with past TEM examinations, the cell with the highest efficiency (15.0%) had no dislocations but did have 11 twin planes.

  16. Highly-efficient THz generation using nonlinear plasmonic metasurfaces (United States)

    Tymchenko, M.; Gomez-Diaz, J. S.; Lee, J.; Belkin, M. A.; Alù, A.


    Nonlinear metasurfaces loaded with multi-quantum-well (MQW) heterostructures constitute a rapidly progressing class of optical devices that combine high nonlinear generation efficiency with an ultrathin profile. Here, we introduce and discuss terahertz (THz) difference-frequency generation (DFG) using MQW-based plasmonic metasurfaces and present a comprehensive theory for their rigorous electromagnetic analysis. We explicitly take into account complex phenomena associated with the local intensity saturation of intersubband transitions and identify fundamental upper-bounds for DFG conversion efficiency. Using this framework, we design and analyze a nonlinear DFG metasurface providing giant DFG nonlinear response and conversion efficiency up to 0.01% at 5.8 THz. Such metasurface can be used to generate 0.15 mW of THz power using pump intensities in the kW cm-2 range. We envision that such DFG metasurfaces can become a platform for uncooled, compact, and highly-efficient continuous-wave THz sources.

  17. High-concentration planar microtracking photovoltaic system exceeding 30% efficiency (United States)

    Price, Jared S.; Grede, Alex J.; Wang, Baomin; Lipski, Michael V.; Fisher, Brent; Lee, Kyu-Tae; He, Junwen; Brulo, Gregory S.; Ma, Xiaokun; Burroughs, Scott; Rahn, Christopher D.; Nuzzo, Ralph G.; Rogers, John A.; Giebink, Noel C.


    Prospects for concentrating photovoltaic (CPV) power are growing as the market increasingly values high power conversion efficiency to leverage now-dominant balance of system and soft costs. This trend is particularly acute for rooftop photovoltaic power, where delivering the high efficiency of traditional CPV in the form factor of a standard rooftop photovoltaic panel could be transformative. Here, we demonstrate a fully automated planar microtracking CPV system solar cell at >660× concentration ratio over a 140∘ full field of view. In outdoor testing over the course of two sunny days, the system operates automatically from sunrise to sunset, outperforming a 17%-efficient commercial silicon solar cell by generating >50% more energy per unit area per day in a direct head-to-head competition. These results support the technical feasibility of planar microtracking CPV to deliver a step change in the efficiency of rooftop solar panels at a commercially relevant concentration ratio.

  18. High efficiency tantalum-based ceramic composite structures (United States)

    Stewart, David A. (Inventor); Leiser, Daniel B. (Inventor); DiFiore, Robert R. (Inventor); Katvala, Victor W. (Inventor)


    Tantalum-based ceramics are suitable for use in thermal protection systems. These composite structures have high efficiency surfaces (low catalytic efficiency and high emittance), thereby reducing heat flux to a spacecraft during planetary re-entry. These ceramics contain tantalum disilicide, molybdenum disilicide and borosilicate glass. The components are milled, along with a processing aid, then applied to a surface of a porous substrate, such as a fibrous silica or carbon substrate. Following application, the coating is then sintered on the substrate. The composite structure is substantially impervious to hot gas penetration and capable of surviving high heat fluxes at temperatures approaching F. and above.

  19. Efficient Unsteady Flow Visualization with High-Order Access Dependencies

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Jiang; Guo, Hanqi; Yuan, Xiaoru


    We present a novel high-order access dependencies based model for efficient pathline computation in unsteady flow visualization. By taking longer access sequences into account to model more sophisticated data access patterns in particle tracing, our method greatly improves the accuracy and reliability in data access prediction. In our work, high-order access dependencies are calculated by tracing uniformly-seeded pathlines in both forward and backward directions in a preprocessing stage. The effectiveness of our proposed approach is demonstrated through a parallel particle tracing framework with high-order data prefetching. Results show that our method achieves higher data locality and hence improves the efficiency of pathline computation.

  20. High-Efficiency Klystron Design for the CLIC Project

    CERN Document Server

    Mollard, Antoine; Peauger, Franck; Plouin, Juliette; Beunas, Armel; Marchesin, Rodolphe


    The CLIC project requests new type of RF sources for the high power conditioning of the accelerating cavities. We are working on the development of a new kind of high-efficiency klystron to fulfill this need. This work is performed under the EuCARD-2 European program and involves theoretical and experimental study of a brand new klystron concept.

  1. High-efficient search and analysis of road lanes

    Directory of Open Access Journals (Sweden)

    Дмитрий Александрович Морозов


    Full Text Available It is developed and implemented high-efficient algorithm for searching and processing elements of road lanes. There are described the most common steps in algorithm logic. The test program, which was written specially for this algorithm, has shown high detection quality. Such program can be used for driver assistance systems

  2. Intermittency-friendly and high-efficiency cogeneration

    DEFF Research Database (Denmark)

    Blarke, Morten; Dotzauer, Erik


    -efficiency and widely applicable option in distributed cogeneration better supporting the co-existence between cogenerators and intermittent renewables in the energy system. The concept involves integrating an efficient high-temperature compression heat pump that uses only waste heat recovered from flue gases as low....... It is found that CHP-HP-FG-CS offers significant reductions in fuel consumption (−8.9%) and operational production costs (−11.4%). The plant’s fuel-to-energy efficiency increases from 88.9 to 95.5%, which is state-of-the-art. The plant’s intermittency-friendliness coefficient Rc improves only marginally due...

  3. High-Efficient Low-Cost Photovoltaics Recent Developments

    CERN Document Server

    Petrova-Koch, Vesselinka; Goetzberger, Adolf


    A bird's-eye view of the development and problems of recent photovoltaic cells and systems and prospects for Si feedstock is presented. High-efficient low-cost PV modules, making use of novel efficient solar cells (based on c-Si or III-V materials), and low cost solar concentrators are in the focus of this book. Recent developments of organic photovoltaics, which is expected to overcome its difficulties and to enter the market soon, are also included.

  4. Design High Efficiency PWM Boost Converter for Wind Power Generation




    The uses of renewable power source toprovide electric power as an alternative become amajor consideration than the costly classical powersources. However, due to research on very lowmaintenancedesigns, small wind turbines becomingmore popularity than economical ways to bring thebenefits of power production to home.The efficiency, size, and cost are the primaryadvantages of switching DC-DC boost powerconverters; it is offer high efficiency performance andprovides power management circuit desig...

  5. High-efficiency "green" quantum dot solar cells. (United States)

    Pan, Zhenxiao; Mora-Seró, Iván; Shen, Qing; Zhang, Hua; Li, Yan; Zhao, Ke; Wang, Jin; Zhong, Xinhua; Bisquert, Juan


    Semiconductor quantum dots (QDs) are extremely interesting materials for the development of photovoltaic devices, but currently the present the drawback is that the most efficient devices have been prepared with toxic heavy metals of Cd or Pb. Solar cells based on "green" QDs--totally free of Cd or Pb--present a modest efficiency of 2.52%. Herein we achieve effective surface passivation of the ternary CuInS2 (CIS) QDs that provides high photovoltaic quality core/shell CIS/ZnS (CIS-Z) QDs, leading to the development of high-efficiency green QD solar cells that surpass the performance of those based on the toxic cadmium and lead chalcogenides QDs. Using wide absorption range QDs, CIS-Z-based quantum dot sensitized solar cell (QDSC) configuration with high QD loading and with the benefit of the recombination reduction with type-I core/shell structure, we boost the power conversion efficiency of Cd- and Pb-free QDSC to a record of 7.04% (with certified efficiency of 6.66%) under AM 1.5G one sun irradiation. This efficiency is the best performance to date for QDSCs and also demonstrates that it is possible to obtain comparable or even better photovoltaic performance from green CIS QDs to the toxic cadmium and lead chalcogenides QDs.

  6. High efficiency switching power amplifiers for multi-band radar (United States)

    Lawler, Jarred; Wells, Justin; Mendez, Sal; Wurth, Tim


    The reduction of size, weight, power, and cost (SWaP-C) of radio frequency (RF) components is becoming increasingly important to meet industry requirements. In meeting the SWaP-C objectives, RF components will be required to be smaller and more power efficient than the current state- of- the- art while sustaining high performance functionality. In compliance with SWaP-C and high performance functionality is a High Efficiency Switching Power Amplifier. This study focuses on the more efficient breed of switching power amplifiers (PAs), particularly the Class F PA with new techniques to operate broadband on multiple radar bands. Efficiencies in the range of 60% to 80% for Class F PAs have been reported in literature; however, this efficiency is only attainable over narrow bandwidths on the order of 10%. Several innovative techniques have been identified to increase the efficiency and operational bandwidth of RF power amplifiers (PAs) for radar applications. The amplifier design also incorporates fast turn on and turn off circuits to achieve switching times of less than one microsecond (μs). This enables the PA to be switched off during the receive period to prevent self-generated noise from corrupting the received signal. Also, high-power transmit and receive (T/R) switches at the antenna feed can be eliminated. A wideband PA enables the design of a multi-band radar, reducing the number of components needed for operation in the L and X bands. A high efficiency PA is also key to reducing battery size and cooling requirements in radar applications.

  7. Enabling High Efficiency Nanoplasmonics with Novel Nanoantenna Architectures (United States)

    Cohen, Moshik; Shavit, Reuven; Zalevsky, Zeev


    Surface plasmon polaritons (SPPs) are propagating excitations that arise from coupling of light with collective electron oscillations. Characterized by high field intensity and nanometric dimensions, SPPs fashion rapid expansion of interest from fundamental and applicative perspectives. However, high metallic losses at optical frequencies still make nanoplasmonics impractical when high absolute efficiency is paramount, with major challenge is efficient plasmon generation in deep nanoscale. Here we introduce the Plantenna, the first reported nanodevice with the potential of addressing these limitations utilizing novel plasmonic architecture. The Plantenna has simple 2D structure, ultracompact dimensions and is fabricated on Silicon chip for future CMOS integration. We design the Plantenna to feed channel (20 nm × 20 nm) nanoplasmonic waveguides, achieving 52% coupling efficiency with Plantenna dimensions of λ3/17,000. We theoretically and experimentally show that the Plantenna enormously outperforms dipole couplers, achieving 28 dB higher efficiency with broad polarization diversity and huge local field enhancement. Our findings confirm the Plantenna as enabling device for high efficiency plasmonic technologies such as quantum nanoplasmonics, molecular strong coupling and plasmon nanolasers.

  8. Low Cost, High Efficiency, High Pressure Hydrogen Storage

    Energy Technology Data Exchange (ETDEWEB)

    Mark Leavitt


    A technical and design evaluation was carried out to meet DOE hydrogen fuel targets for 2010. These targets consisted of a system gravimetric capacity of 2.0 kWh/kg, a system volumetric capacity of 1.5 kWh/L and a system cost of $4/kWh. In compressed hydrogen storage systems, the vast majority of the weight and volume is associated with the hydrogen storage tank. In order to meet gravimetric targets for compressed hydrogen tanks, 10,000 psi carbon resin composites were used to provide the high strength required as well as low weight. For the 10,000 psi tanks, carbon fiber is the largest portion of their cost. Quantum Technologies is a tier one hydrogen system supplier for automotive companies around the world. Over the course of the program Quantum focused on development of technology to allow the compressed hydrogen storage tank to meet DOE goals. At the start of the program in 2004 Quantum was supplying systems with a specific energy of 1.1-1.6 kWh/kg, a volumetric capacity of 1.3 kWh/L and a cost of $73/kWh. Based on the inequities between DOE targets and Quantum’s then current capabilities, focus was placed first on cost reduction and second on weight reduction. Both of these were to be accomplished without reduction of the fuel system’s performance or reliability. Three distinct areas were investigated; optimization of composite structures, development of “smart tanks” that could monitor health of tank thus allowing for lower design safety factor, and the development of “Cool Fuel” technology to allow higher density gas to be stored, thus allowing smaller/lower pressure tanks that would hold the required fuel supply. The second phase of the project deals with three additional distinct tasks focusing on composite structure optimization, liner optimization, and metal.

  9. High efficiency III-nitride light-emitting diodes (United States)

    Crawford, Mary; Koleske, Daniel; Cho, Jaehee; Zhu, Di; Noemaun, Ahmed; Schubert, Martin F; Schubert, E. Fred


    Tailored doping of barrier layers enables balancing of the radiative recombination among the multiple-quantum-wells in III-Nitride light-emitting diodes. This tailored doping enables more symmetric carrier transport and uniform carrier distribution which help to reduce electron leakage and thus reduce the efficiency droop in high-power III-Nitride LEDs. Mitigation of the efficiency droop in III-Nitride LEDs may enable the pervasive market penetration of solid-state-lighting technologies in high-power lighting and illumination.

  10. High Efficient Bidirectional Battery Converter for residential PV Systems

    DEFF Research Database (Denmark)

    Pham, Cam; Kerekes, Tamas; Teodorescu, Remus


    Photovoltaic (PV) installation is suited for the residential environment and the generation pattern follows the distribution of residential power consumption in daylight hours. In the cases of unbalance between generation and demand, the Smart PV with its battery storage can absorb or inject...... the power to balance it. High efficient bidirectional converter for the battery storage is required due high system cost and because the power is processed twice. A 1.5kW prototype is designed and built with CoolMOS and SiC diodes, >;95% efficiency has been obtained with 200 kHz hard switching....

  11. Experimental Realization of High-Efficiency Counterfactual Computation. (United States)

    Kong, Fei; Ju, Chenyong; Huang, Pu; Wang, Pengfei; Kong, Xi; Shi, Fazhan; Jiang, Liang; Du, Jiangfeng


    Counterfactual computation (CFC) exemplifies the fascinating quantum process by which the result of a computation may be learned without actually running the computer. In previous experimental studies, the counterfactual efficiency is limited to below 50%. Here we report an experimental realization of the generalized CFC protocol, in which the counterfactual efficiency can break the 50% limit and even approach unity in principle. The experiment is performed with the spins of a negatively charged nitrogen-vacancy color center in diamond. Taking advantage of the quantum Zeno effect, the computer can remain in the not-running subspace due to the frequent projection by the environment, while the computation result can be revealed by final detection. The counterfactual efficiency up to 85% has been demonstrated in our experiment, which opens the possibility of many exciting applications of CFC, such as high-efficiency quantum integration and imaging.

  12. High extraction efficiency ultraviolet light-emitting diode (United States)

    Wierer, Jonathan; Montano, Ines; Allerman, Andrew A.


    Ultraviolet light-emitting diodes with tailored AlGaN quantum wells can achieve high extraction efficiency. For efficient bottom light extraction, parallel polarized light is preferred, because it propagates predominately perpendicular to the QW plane and into the typical and more efficient light escape cones. This is favored over perpendicular polarized light that propagates along the QW plane which requires multiple, lossy bounces before extraction. The thickness and carrier density of AlGaN QW layers have a strong influence on the valence subband structure, and the resulting optical polarization and light extraction of ultraviolet light-emitting diodes. At Al>0.3, thinner QW layers (<2.5 nm are preferred) result in light preferentially polarized parallel to the QW plane. Also, active regions consisting of six or more QWs, to reduce carrier density, and with thin barriers, to efficiently inject carriers in all the QWs, are preferred.

  13. A metamaterial electromagnetic energy rectifying surface with high harvesting efficiency (United States)

    Duan, Xin; Chen, Xing; Zhou, Lin


    A novel metamaterial rectifying surface (MRS) for electromagnetic energy capture and rectification with high harvesting efficiency is presented. It is fabricated on a three-layer printed circuit board, which comprises an array of periodic metamaterial particles in the shape of mirrored split rings, a metal ground, and integrated rectifiers employing Schottky diodes. Perfect impedance matching is engineered at two interfaces, i.e. one between free space and the surface, and the other between the metamaterial particles and the rectifiers, which are connected through optimally positioned vias. Therefore, the incident electromagnetic power is captured with almost no reflection by the metamaterial particles, then channeled maximally to the rectifiers, and finally converted to direct current efficiently. Moreover, the rectifiers are behind the metal ground, avoiding the disturbance of high power incident electromagnetic waves. Such a MRS working at 2.45 GHz is designed, manufactured and measured, achieving a harvesting efficiency up to 66.9% under an incident power density of 5 mW/cm2, compared with a simulated efficiency of 72.9%. This high harvesting efficiency makes the proposed MRS an effective receiving device in practical microwave power transmission applications.

  14. Capture efficiency of portable high efficiency air filtration devices used during building construction activities. (United States)

    Newcomer, Derek A; LaPuma, Peter; Brandys, Robert; Northcross, Amanda


    The portable high efficiency air filtration (PHEAF) device is used to control particulate matter (PM) generated from construction-type activities occurring within the built environment. Examples of activities where PHEAF devices are mobilized include building renovation, asbestos abatement, remediation of microbial contamination and lead-based paint projects. Designed for use on short-term, temporary projects the PHEAF device captures airborne PM using a high efficiency particulate air (HEPA) filter. This study sought to evaluate the capture efficiency of the PHEAF device in a field setting. An aerosol generator and photometer were used to measure particle penetration through 85 PHEAF devices. Average overall capture efficiency ranged from 41.78% to ≥99.97% with more than 88% of the tests failing to achieve 99.97% capture efficiency. Approximately 73% of the PHEAF device sample population failed to demonstrated HEPA performance criteria during any test round. Higher occurrence of PM concentrations measured around the perimeter of the filter suggested the presence of bypass leakage. While PHEAF devices were effective in capturing a significant quantity of aerosol test agent, these findings suggest that routine testing of the PHEAF device should be conducted to validate performance.

  15. Processing technology for high efficiency silicon solar cells (United States)

    Spitzer, M. B.; Keavney, C. J.


    Recent advances in silicon solar cell processing have led to attainment of conversion efficiency approaching 20%. The basic cell design is investigated and features of greatest importance to achievement of 20% efficiency are indicated. Experiments to separately optimize high efficiency design features in test structures are discussed. The integration of these features in a high efficiency cell is examined. Ion implantation has been used to achieve optimal concentrations of emitter dopant and junction depth. The optimization reflects the trade-off between high sheet conductivity, necessary for high fill factor, and heavy doping effects, which must be minimized for high open circuit voltage. A second important aspect of the design experiments is the development of a passivation process to minimize front surface recombination velocity. The manner in which a thin SiO2 layer may be used for this purpose is indicated without increasing reflection losses, if the antireflection coating is properly designed. Details are presented of processing intended to reduce recombination at the contact/Si interface. Data on cell performance (including CZ and ribbon) and analysis of loss mechanisms are also presented.

  16. Highly efficient light management for perovskite solar cells (United States)

    Wang, Dong-Lin; Cui, Hui-Juan; Hou, Guo-Jiao; Zhu, Zhen-Gang; Yan, Qing-Bo; Su, Gang


    Organic-inorganic halide perovskite solar cells have enormous potential to impact the existing photovoltaic industry. As realizing a higher conversion efficiency of the solar cell is still the most crucial task, a great number of schemes were proposed to minimize the carrier loss by optimizing the electrical properties of the perovskite solar cells. Here, we focus on another significant aspect that is to minimize the light loss by optimizing the light management to gain a high efficiency for perovskite solar cells. In our scheme, the slotted and inverted prism structured SiO2 layers are adopted to trap more light into the solar cells, and a better transparent conducting oxide layer is employed to reduce the parasitic absorption. For such an implementation, the efficiency and the serviceable angle of the perovskite solar cell can be promoted impressively. This proposal would shed new light on developing the high-performance perovskite solar cells. PMID:26733112

  17. Highly efficient light management for perovskite solar cells

    CERN Document Server

    Wang, Dong-Lin; Hou, Guo-Jiao; Zhu, Zhen-Gang; Yan, Qing-Bo; Su, Gang


    Organic-inorganic halide perovskite solar cells have enormous potential to impact the existing photovoltaic industry. As realizing a higher conversion efficiency of the solar cell is still the most crucial task, a great number of schemes were proposed to minimize the carrier loss by optimizing the electrical properties of the perovskite solar cells. Here, we focus on another significant aspect that is to minimize the light loss by optimizing the light management to gain a high efficiency for perovskite solar cells. In our scheme, the slotted and inverted prism structured SiO2 layers are adopted to trap more light into the solar cells, and a better transparent conducting oxide layer is employed to reduce the parasitic absorption. For such an implementation, the efficiency and the serviceable angle of the perovskite solar cell can be promoted impressively. This proposal would shed new light on developing the high-performance perovskite solar cells.

  18. Highly efficient light management for perovskite solar cells (United States)

    Wang, Dong-Lin; Cui, Hui-Juan; Hou, Guo-Jiao; Zhu, Zhen-Gang; Yan, Qing-Bo; Su, Gang


    Organic-inorganic halide perovskite solar cells have enormous potential to impact the existing photovoltaic industry. As realizing a higher conversion efficiency of the solar cell is still the most crucial task, a great number of schemes were proposed to minimize the carrier loss by optimizing the electrical properties of the perovskite solar cells. Here, we focus on another significant aspect that is to minimize the light loss by optimizing the light management to gain a high efficiency for perovskite solar cells. In our scheme, the slotted and inverted prism structured SiO2 layers are adopted to trap more light into the solar cells, and a better transparent conducting oxide layer is employed to reduce the parasitic absorption. For such an implementation, the efficiency and the serviceable angle of the perovskite solar cell can be promoted impressively. This proposal would shed new light on developing the high-performance perovskite solar cells.

  19. Potential high efficiency solar cells: Applications from space photovoltaic research (United States)

    Flood, D. J.


    NASA involvement in photovoltaic energy conversion research development and applications spans over two decades of continuous progress. Solar cell research and development programs conducted by the Lewis Research Center's Photovoltaic Branch have produced a sound technology base not only for the space program, but for terrestrial applications as well. The fundamental goals which have guided the NASA photovoltaic program are to improve the efficiency and lifetime, and to reduce the mass and cost of photovoltaic energy conversion devices and arrays for use in space. The major efforts in the current Lewis program are on high efficiency, single crystal GaAs planar and concentrator cells, radiation hard InP cells, and superlattice solar cells. A brief historical perspective of accomplishments in high efficiency space solar cells will be given, and current work in all of the above categories will be described. The applicability of space cell research and technology to terrestrial photovoltaics will be discussed.

  20. High efficiency green LEDs using II-VI color converters (United States)

    Miller, Thomas J.; Haase, Michael A.; Sun, Xiaoguang; Hao, Bing; Zhang, Junying; Smith, Terry L.; Ballen, Todd; Xie, Junqing; Barnes, Amy S.; Kecman, Fedja; Yang, Joseph; Thielen, James; Leatherdale, Catherine A.; Wirth, Ralph; Biebersdorf, Andreas; Engl, Karl; Groetsch, Stefan


    II-VI semiconductors can exhibit strong photoluminescence throughout the visible spectrum and are excellent candidates for filling the so-called "green gap". We report on the performance of green color-converted LEDs fabricated by bonding CdMgZnSe multiple quantum well structures to high-efficiency blue-emitting GaInN LEDs. A device efficacy of 181 lm/W at 537 nm (dominant) is measured under room temperature, 350 mA/mm2 quasi-cw conditions, more than twice as efficient as typical commercial green LEDs today. The thermal roll-off is shown to be comparable to that of typical green GaInN LEDs. Finally, the implications of the availability of high-efficiency, narrow-band, green and yellow emitters in display applications will be discussed.

  1. Disruption of Higher Order DNA Structures in Friedreich's Ataxia (GAA)n Repeats by PNA or LNA Targeting. (United States)

    Bergquist, Helen; Rocha, Cristina S J; Álvarez-Asencio, Rubén; Nguyen, Chi-Hung; Rutland, Mark W; Smith, C I Edvard; Good, Liam; Nielsen, Peter E; Zain, Rula


    Expansion of (GAA)n repeats in the first intron of the Frataxin gene is associated with reduced mRNA and protein levels and the development of Friedreich's ataxia. (GAA)n expansions form non-canonical structures, including intramolecular triplex (H-DNA), and R-loops and are associated with epigenetic modifications. With the aim of interfering with higher order H-DNA (like) DNA structures within pathological (GAA)n expansions, we examined sequence-specific interaction of peptide nucleic acid (PNA) with (GAA)n repeats of different lengths (short: n=9, medium: n=75 or long: n=115) by chemical probing of triple helical and single stranded regions. We found that a triplex structure (H-DNA) forms at GAA repeats of different lengths; however, single stranded regions were not detected within the medium size pathological repeat, suggesting the presence of a more complex structure. Furthermore, (GAA)4-PNA binding of the repeat abolished all detectable triplex DNA structures, whereas (CTT)5-PNA did not. We present evidence that (GAA)4-PNA can invade the DNA at the repeat region by binding the DNA CTT strand, thereby preventing non-canonical-DNA formation, and that triplex invasion complexes by (CTT)5-PNA form at the GAA repeats. Locked nucleic acid (LNA) oligonucleotides also inhibited triplex formation at GAA repeat expansions, and atomic force microscopy analysis showed significant relaxation of plasmid morphology in the presence of GAA-LNA. Thus, by inhibiting disease related higher order DNA structures in the Frataxin gene, such PNA and LNA oligomers may have potential for discovery of drugs aiming at recovering Frataxin expression.

  2. Disruption of Higher Order DNA Structures in Friedreich’s Ataxia (GAA)n Repeats by PNA or LNA Targeting (United States)

    Bergquist, Helen; Rocha, Cristina S. J.; Álvarez-Asencio, Rubén; Nguyen, Chi-Hung; Rutland, Mark. W.; Smith, C. I. Edvard; Good, Liam; Nielsen, Peter E.; Zain, Rula


    Expansion of (GAA)n repeats in the first intron of the Frataxin gene is associated with reduced mRNA and protein levels and the development of Friedreich’s ataxia. (GAA)n expansions form non-canonical structures, including intramolecular triplex (H-DNA), and R-loops and are associated with epigenetic modifications. With the aim of interfering with higher order H-DNA (like) DNA structures within pathological (GAA)n expansions, we examined sequence-specific interaction of peptide nucleic acid (PNA) with (GAA)n repeats of different lengths (short: n=9, medium: n=75 or long: n=115) by chemical probing of triple helical and single stranded regions. We found that a triplex structure (H-DNA) forms at GAA repeats of different lengths; however, single stranded regions were not detected within the medium size pathological repeat, suggesting the presence of a more complex structure. Furthermore, (GAA)4-PNA binding of the repeat abolished all detectable triplex DNA structures, whereas (CTT)5-PNA did not. We present evidence that (GAA)4-PNA can invade the DNA at the repeat region by binding the DNA CTT strand, thereby preventing non-canonical-DNA formation, and that triplex invasion complexes by (CTT)5-PNA form at the GAA repeats. Locked nucleic acid (LNA) oligonucleotides also inhibited triplex formation at GAA repeat expansions, and atomic force microscopy analysis showed significant relaxation of plasmid morphology in the presence of GAA-LNA. Thus, by inhibiting disease related higher order DNA structures in the Frataxin gene, such PNA and LNA oligomers may have potential for discovery of drugs aiming at recovering Frataxin expression. PMID:27846236

  3. Innovation development for highly energy-efficient housing

    NARCIS (Netherlands)

    Mlecnik, E.


    Buildings account for 40% of EU final energy demand and policy developments like the Energy Performance of Buildings Directive are stimulating the innovation development for nearly zero-energy housing. However, businesses switching to innovative products for highly energy-efficient houses is a

  4. Highly efficient deep ultraviolet generation by sum-frequency mixing ...

    Indian Academy of Sciences (India)

    enhancement in the generated energy realized is 2.0 over the single crystal arrangement and 1.25 relative to the NWOC arrangement. The energy conversion efficiency as high as 36.4% has been obtained with two BBO crystals under WOC arrangements with the pump energy as low as 1.66 mJ for the dye laser radiation ...

  5. Highly efficient epoxidation of alkenes with m-chloroperbenzoic acid ...

    Indian Academy of Sciences (India)

    Highly efficient epoxidation of alkenes with m-chloroperbenzoic acid catalyzed by nanomagnetic Co(III)@Fe₃O₄/SiO₂ salen complex ... The heterogeneous nanocatalyst was characterized by X-ray diffraction (XRD), thermogravimetric analysis (TGA), transmission electron microscopy (TEM), Fourier transform infrared ...

  6. High-efficiency regeneration of peanut ( Arachis hypogaea L.) plants ...

    African Journals Online (AJOL)

    A high-efficiency regeneration system for peanut plants was established. The regeneration frequency of leaf discs reached 40.9% on Murashige and Skoog medium supplemented with 0.5 mg l-1 naphthylacetic acid and 0.5 mg l-1 thidiazuron. The regenerated shoots elongated, developed roots and produced seeds.

  7. A highly efficient method for Agrobacterium mediated transformation ...

    African Journals Online (AJOL)

    A highly efficient method for Agrobacterium mediated transformation in elite rice varieties ( Oryza sativa L. spp. indica) ... Optimized transformation conditions were established using Agrobacterium strain EHA105, which carries a virulent plasmid, pCAMBIA1301. A modified Murashige and Skoog (MS) medium supplemented ...

  8. Highly Efficient Formylation of Alcohols, Thiols and Aniline ...

    African Journals Online (AJOL)

    A simple, rapid and efficient microwave-assisted procedure for the formylation of aniline derivatives and alcohols, using a heterogeneous (HCOOH/SiO2) system under solvent-free conditions is reported. The method is applied to a set of amines, alcohols and thiols and short reaction times (<10 min) with high yields are ...

  9. Nickel nanoparticles: A highly efficient catalyst for one pot synthesis ...

    Indian Academy of Sciences (India)

    Nickel nanoparticles: A highly efficient catalyst for one pot synthesis of tetraketones and biscoumarins. JITENDER M KHURANA. ∗ and KANIKA VIJ. Department of Chemistry, University of Delhi, Delhi 110 007, India e-mail: MS received 18 March 2011; revised 17 November 2011; accepted 20 ...

  10. High efficiency solar cells for laser power beaming applications (United States)

    Jain, Raj K.; Landis, G. A.


    Understanding solar cell response to pulsed laser outputs is important for the evaluation of power beaming applications. The time response of high efficiency GaAs and silicon solar cells to a 25 nS monochromatic pulse input is described. The PC-1D computer code is used to analyze the cell current during and after the pulse for various conditions.

  11. Highly efficient light-emitting diodes based on intramolecular rotation

    CERN Document Server

    Di, Dawei; Yang, Le; Jones, Saul; Friend, Richard H; Linnolahti, Mikko; Bochmann, Manfred; Credgington, Dan


    The efficiency of an organic light-emitting diode (OLED) is fundamentally governed by the spin of recombining electron-hole pairs (singlet and triplet excitons), since triplets cannot usually emit light. The singlet-triplet energy gap, a key factor for efficient utilization of triplets, is normally positive. Here we show that in a family of materials with amide donor and carbene acceptor moieties linked by a metal, this energy gap for singlet and triplet excitons with charge-transfer character can be tuned from positive to negative values via the rotation of donor and acceptor about the metal-amide bond. When the gap is close to zero, facile intersystem crossing is possible, enabling efficient emission from singlet excitons. We demonstrate solution-processed LEDs with exceptionally high quantum efficiencies (near-100% internal and >27% external quantum efficiencies), and current and power efficiencies (87 cd/A and 75 lm/W) comparable to, or exceeding, those of state-of-the-art vacuum-processed OLEDs and quant...

  12. Multi-wavelength high efficiency laser system for lidar applications (United States)

    Willis, Christina C. C.; Culpepper, Charles; Burnham, Ralph


    Motivated by the growing need for more efficient, high output power laser transmitters, we demonstrate a multi-wavelength laser system for lidar-based applications. The demonstration is performed in two stages, proving energy scaling and nonlinear conversion independently for later combination. Energy scaling is demonstrated using a 1064 nm MOPA system which employs two novel ceramic Nd:YAG slab amplifiers, the structure of which is designed to improve the amplifier's thermal performance and energy extraction via three progressive doping stages. This structure improved the extraction efficiency by 19% over previous single-stage dopant designs. A maximum energy of 34 mJ was produced at 500 Hz with a 10.8 ns pulse duration. High efficiency non-linear conversion from 1064 nm to 452 nm is demonstrated using a KTP ring OPO with a BBO intra-cavity doubler pumped with 50 Hz, 16 ns 1064 nm pulses. The OPO generates 1571 nm signal which is frequency doubled to 756 nm by the BBO. Output 786 nm pulses are mixed with the 1064 nm pump pulses to generate 452 nm. A conversion efficiency of 17.1% was achieved, generating 3 mJ of 452 nm pulses of 7.8 ns duration. Pump power was limited by intra-cavity damage thresholds, and in future experiments we anticipate >20% conversion efficiency.

  13. High efficiency inductive output tubes with intense annular electron beams (United States)

    Appanam Karakkad, J.; Matthew, D.; Ray, R.; Beaudoin, B. L.; Narayan, A.; Nusinovich, G. S.; Ting, A.; Antonsen, T. M.


    For mobile ionospheric heaters, it is necessary to develop highly efficient RF sources capable of delivering radiation in the frequency range from 3 to 10 MHz with an average power at a megawatt level. A promising source, which is capable of offering these parameters, is a grid-less version of the inductive output tube (IOT), also known as a klystrode. In this paper, studies analyzing the efficiency of grid-less IOTs are described. The basic trade-offs needed to reach high efficiency are investigated. In particular, the trade-off between the peak current and the duration of the current micro-pulse is analyzed. A particle in the cell code is used to self-consistently calculate the distribution in axial and transverse momentum and in total electron energy from the cathode to the collector. The efficiency of IOTs with collectors of various configurations is examined. It is shown that the efficiency of IOTs can be in the 90% range even without using depressed collectors.

  14. Heat pumps; Synergy of high efficiency and low carbon electricity

    Energy Technology Data Exchange (ETDEWEB)

    Koike, Akio


    Heat pump is attracting wide attention for its high efficiency to utilize inexhaustible and renewable ambient heat in the environment. With its rapid innovation and efficiency improvement, this technology has a huge potential to reduce CO2 emissions by replacing currently widespread fossil fuel combustion systems to meet various heat demands from the residential, commercial and industrial sectors. Barriers to deployment such as low public awareness and a relatively long pay-back period do exist, so it is strongly recommended that each country implement policies to promote heat pumps as a renewable energy option and an effective method to combat global warming.

  15. Nanoporous Carbon Nitride: A High Efficient Filter for Seawater Desalination

    CERN Document Server

    Li, Weifeng; Zhou, Hongcai; Zhang, Xiaoming; Zhao, Mingwen


    The low efficiency of commercially-used reverse osmosis (RO) membranes has been the main obstacle in seawater desalination application. Here, we report the auspicious performance, through molecular dynamics simulations, of a seawater desalination filter based on the recently-synthesized graphene-like carbon nitride (g-C2N) [Nat. Commun., 2015, 6, 6486]. Taking advantage of the inherent nanopores and excellent mechanical properties of g-C2N filter, highly efficient seawater desalination can be achieved by modulating the nanopores under tensile strain. The water permeability can be improved by two orders of magnitude compared to RO membranes, which offers a promising approach to the global water shortage solution.

  16. Consequences of high-frequency operation on EUV source efficiency (United States)

    Sizyuk, Tatyana


    A potential problem of future extreme ultraviolet (EUV) sources, required for high volume manufacture regimes, can be related to the contamination of the chamber environment by products of preceding laser pulse/droplet interactions. Implementation of high, 100 kHz and higher, repetition rate of EUV sources using Sn droplets ignited with laser pulses can cause high accumulation of tin in the chamber in the form of vapor, fine mist, or fragmented clusters. In this work, the effects of the residual tin accumulation in the EUV chamber in dependence on laser parameters and mitigation system efficiency were studied. The effect of various pressures of tin vapor on the CO2 and Nd:YAG laser beam propagation and on the size, the intensity, and the resulting efficiency of the EUV sources was analyzed. The HEIGHTS 3D package was used for this analysis to study the effect of residual background pressure and spatial distribution on EUV photon emission and collection. It was found that background pressure in the range of 1-5 Pa does not significantly influence the EUV source produced by CO2 lasers. A larger volume with this pressure condition, however, can reduce the efficiency of the source. However, an optimized volume of mix with proper density could increase the efficiency of the sources produced by CO2 lasers.

  17. Optically Thin Metallic Films for High-radiative-efficiency Plasmonics

    CERN Document Server

    Yang, Yi; Hsu, Chia Wei; Miller, Owen D; Joannopoulos, John D; Soljačić, Marin


    Plasmonics enables deep-subwavelength concentration of light and has become important for fundamental studies as well as real-life applications. Two major existing platforms of plasmonics are metallic nanoparticles and metallic films. Metallic nanoparticles allow efficient coupling to far field radiation, yet their synthesis typically leads to poor material quality. Metallic films offer substantially higher quality materials, but their coupling to radiation is typically jeopardized due to the large momentum mismatch with free space. Here, we propose and theoretically investigate optically thin metallic films as an ideal platform for high-radiative-efficiency plasmonics. For far-field scattering, adding a thin high-quality metallic substrate enables a higher quality factor while maintaining the localization and tunability that the nanoparticle provides. For near-field spontaneous emission, a thin metallic substrate, of high quality or not, greatly improves the field overlap between the emitter environment and ...

  18. Broadband circularly polarizing dichroism with high efficient plasmonic helical surface. (United States)

    Hu, Jingpei; Zhao, Xiaonan; Li, Ruibin; Zhu, Aijiao; Chen, Linghua; Lin, Yu; Cao, Bing; Zhu, Xiaojun; Wang, Chinhua


    We propose and experimentally demonstrate a broadband and high efficient circularly polarizing dichroism using a simple single-cycle and single-helical plasmonic surface array arranged in square lattice. Two types of helical surface structures (partially or completely covered with a gold film) are investigated. It is shown that the circular polarization dichroism in the mid-IR range (3µm - 5µm) can reach 80% (when the surface is partially covered with gold) or 65% (when the surface is completely covered with gold) with a single-cycle and single-helical surface. Experimental fabrications of the proposed helical plasmonic surface are implemented with direct 3D laser writing followed by electron beam evaporation deposition of gold. The experimental evaluations of the circular polarization dichroism are in excellent agreement with the simulation. The proposed helical surface structure is of advantages of easy-fabrication, high-dichroism and scalable to other frequencies as a high efficient broadband circular polarizer.

  19. Highly efficient singular surface plasmon generation by achiral apertures

    CERN Document Server

    Jiang, Quanbo; Bellessa, Joel; Huant, Serge; Genet, Cyriaque; Drezet, Aurélien


    We report a highly efficient generation of singular surface plasmon (SP) field by an achiral plasmonic structure consisting of $\\Lambda$-shaped apertures. Our quantitative analysis based on leakage radiation microscopy (LRM) demonstrates that the induced spin-orbit coupling can be tuned by adjusting the apex angle of the $\\Lambda$-shaped aperture. Specifically, the array of $\\Lambda$-shaped apertures with the apex angle $60^\\circ$ is shown to give rise to the directional coupling efficiency. The ring of $\\Lambda$-shaped apertures with the apex angle $60^\\circ$ realized to generate the maximum extinction ratio (ER=11) for the SP singularities between two different polarization states. This result provides a more efficient way for developing SP focusing and SP vortex in the field of nanophotonics such as optical tweezers.

  20. Functionalized superparamagnetic nanoparticles for highly-efficient gene delivery. (United States)

    Wang, Xiaowen; Chen, Benke; Yang, Xin; Zhang, Jieying; Zhao, Linyun; Tang, Jintian


    Functionalized superparamagnetic iron oxide nanoparticles (SPIONs) can play crucial roles for medical applications such as cancer magnetic induction hyperthermia, magnetic resonance imaging, and magnetofection. Gene therapy is an emerging area of biomedicine and has the potential to revolutionize the treatment of human disease. Herein we report the results of modified magnetic nanoparticles coated with protamine containing nuclear localization signal sequences. Thermogravimetric analysis, X-ray powder diffraction, cellular uptake, and gene magnetofection efficiency of protamine modified SPIONs were evaluated. SPIONs modified with protamine resulted in more cellular uptake and higher-efficient gene transfection in HepG2 cells. The work demonstrates that protamine modified SPIONs can be used as a novel kind of highly efficient magnetic mediator for magnetic induction hyperthermia combined with gene therapy.

  1. Broadband highly-efficient dielectric metadevices for polarization control

    CERN Document Server

    Kruk, Sergey; Kravchenko, Ivan; Miroshnichenko, Andrey; Neshev, Dragomir N; Kivshar, Yuri S


    Metadevices based on dielectric nanostructured surfaces with both electric and magnetic Mie-type resonances have resulted in the best efficiency to date for functional flat optics with only one disadvantage: narrow operational bandwidth. Here we experimentally demonstrate broadband transparent all-dielectric metasurfaces for highly efficient polarization manipulation. We utilize the generalized Huygens principle with a superposition of the scattering contributions from several electric and magnetic multipolar modes of the constituent meta-atoms to achieve destructive interference in reflection over a large spectral bandwidth. By employing this novel concept, we demonstrate reflectionless (~90% transmission) half-wave plates, quarter-wave plates, and vector beam q-plates that can operate across multiple telecom bands with ~99% polarization conversion efficiency.

  2. Predicting high harmonic ion cyclotron heating efficiency in Tokamak plasmas. (United States)

    Green, D L; Berry, L A; Chen, G; Ryan, P M; Canik, J M; Jaeger, E F


    Observations of improved radio frequency (rf) heating efficiency in ITER relevant high-confinement (H-)mode plasmas on the National Spherical Tokamak Experiment are investigated by whole-device linear simulation. The steady-state rf electric field is calculated for various antenna spectra and the results examined for characteristics that correlate with observations of improved or reduced rf heating efficiency. We find that launching toroidal wave numbers that give fast-wave propagation in the scrape-off plasma excites large amplitude (∼kV m(-1)) coaxial standing modes between the confined plasma density pedestal and conducting vessel wall. Qualitative comparison with measurements of the stored plasma energy suggests that these modes are a probable cause of degraded heating efficiency.

  3. A high-efficiency, low-cost aeolian sand trap (United States)

    Sherman, D. J.; Swann, C.; Barron, J. D.


    We present a design for an aeolian sand trap that is based on the streamer trap concept used in sediment transport studies. The trap is inexpensive, has excellent trapping efficiency, is durable, and easy to use. It is fabricated from stainless steel that is cut and bent to form a frame to support a fine nylon mesh. Typical trap openings are 100 mm wide and 25, 50, or 100 mm high. Traps are 250 mm long, and are stackable to measure vertical characteristics of saltation. The nylon mesh has 64 μm openings that comprise 47% of the area of the material. Aerodynamic efficiency was tested in a wind tunnel, and sediment trapping efficiency evaluated in field deployments. Both evaluations support the use of this trap for short-term measurements.

  4. High-Efficiency Harmonically Terminated Diode and Transistor Rectifiers

    Energy Technology Data Exchange (ETDEWEB)

    Roberg, M; Reveyrand, T; Ramos, I; Falkenstein, EA; Popovic, Z


    This paper presents a theoretical analysis of harmonically terminated high-efficiency power rectifiers and experimental validation on a class-C single Schottky-diode rectifier and a class-F-1 GaN transistor rectifier. The theory is based on a Fourier analysis of current and voltage waveforms, which arise across the rectifying element when different harmonic terminations are presented at its terminals. An analogy to harmonically terminated power amplifier (PA) theory is discussed. From the analysis, one can obtain an optimal value for the dc load given the RF circuit design. An upper limit on rectifier efficiency is derived for each case as a function of the device on-resistance. Measured results from fundamental frequency source-pull measurement of a Schottky diode rectifier with short-circuit terminations at the second and third harmonics are presented. A maximal device rectification efficiency of 72.8% at 2.45 GHz matches the theoretical prediction. A 2.14-GHz GaN HEMT rectifier is designed based on a class-F-1 PA. The gate of the transistor is terminated in an optimal impedance for self-synchronous rectification. Measurements of conversion efficiency and output dc voltage for varying gate RF impedance, dc load, and gate bias are shown with varying input RF power at the drain. The rectifier demonstrates an efficiency of 85% for a 10-W input RF power at the transistor drain with a dc voltage of 30 V across a 98-Omega resistor.

  5. Exploring options to combine high yields with high nitrogen use efficiencies in irrigated rice in China

    NARCIS (Netherlands)

    Jing, Q.; Bouman, B.A.M.; Hengsdijk, H.; Keulen, van H.; Cao, W.


    In Jiangsu province, Southeast China, high irrigated rice yields (6-8000 kg ha(-1)) are supported by high nitrogen (N) fertilizer inputs (260-300 kg N ha(-1)) and low fertilizer N use efficiencies (recoveries of 30-35%). Improvement of fertilizer N use efficiency can increase farmers' profitability

  6. High Efficiency, High Temperature Foam Core Heat Exchanger for Fission Surface Power Systems, Phase II Project (United States)

    National Aeronautics and Space Administration — Fission-based power systems with power levels of 30 to ≥100 kWe will be needed for planetary surface bases. Development of high temperature, high efficiency...

  7. High-Power, High-Efficiency 1.907nm Diode Lasers Project (United States)

    National Aeronautics and Space Administration — nLight developed high-power, high-efficiency laser diodes emitting at 1907nm for the pumping of solid-state lasers during the Phase I. The innovation brought to bear...

  8. High-Power, High-Efficiency 1.907nm Diode Lasers Project (United States)

    National Aeronautics and Space Administration — nLight proposes to develop high-power, high-efficiency laser diodes emitting at 1907nm. Performance is expected to improve from the current state-of-the-art...

  9. High Efficiency, High Output Plastic Melt Waste Compactor (HEHO-PMWC) Project (United States)

    National Aeronautics and Space Administration — The innovative High Efficiency, High Output Plastic Melt Waste Compactor (HEHO-PMWC) is a trash dewatering and volume reduction system that uses heat melt compaction...

  10. Highly efficient immobilization of glycosylated enzymes into polyurethane foams. (United States)

    Bakker, M; van De Velde, F; van Rantwijk, F; Sheldon, R A


    Glycosylated enzymes, including aminoacylase from Aspergillus melleus, chloroperoxidase from Caldariomyces fumago, and phytase from Aspergillus ficuum, were covalently immobilized into polyurethane foams with very high enzyme loadings of up to 0.2 g protein per gram dry foam. The immobilization efficiency (retained activity) ranged from 100% at a low loading to 60% at high loadings. In contrast to many other immobilization methods no leaching of the enzyme from the support took place under the reaction conditions. In short, a universal method for the immobilization of enzymes from fungal sources was developed, affording a highly active, stable, and reusable biocatalyst. Copyright 2000 John Wiley & Sons, Inc.

  11. a Study of High Efficiency Thin Thermophotovoltaic Solar Cells. (United States)

    Vera, Eduardo Sobrino


    High conversion efficiency of solar energy into electrical energy is possible if the incident radiation is first absorbed by an intermediate absorber and then re-emitted onto a photovoltaic (PV) solar cell. This mode of operation is known as solar thermophotovoltaic (TPV) energy conversion. This thesis explores the limits on performance of TPV systems based on germanium in which the source temperature and the opto-electronic structure of the germanium PV cell are varied and optimized with respect to overall radiant energy conversion efficiency. The principal characteristic of the optimized high efficiency TPV germanium cells is that they are thin p-n junction solar cells which incorporate minority carrier mirrors (MCM) and optical mirrors (OM) at the front and back surfaces of the device examined. In this study, the role of MCM and OM is studied theoretically by solving the minority carrier diffusion equation in the n- and p-type quasineutral regions of the cell with the appropriate boundary conditions at the end of these regions and an appropriate minority carrier generation function. The high theoretical efficiency calculated for these thin structures derives from the simultaneous use of optical and electronic reflection. The calculations presented here determine the theoretical upper limit to TPV conversion efficiency and show the dependence of this limit on cell geometry, resistivity, surface recombination and input density. In addition, TPV systems based on more than one PV cell, each utilizing a different photovoltaically active semiconductor are also considered. A number of possible TPV systems are treated within this theoretical framework. When blackbody thermal radiation sources having temperatures in the range 1500-2000 C are considered, the upper limit efficiency is found to be about 22% for an optimum design germanium cell 90 microns thick and about 26% for a two-junction silicon-germanium tandem cell arrangement 50 and 90 microns thick, respectively

  12. Lightweight High Efficiency Electric Motors for Space Applications (United States)

    Robertson, Glen A.; Tyler, Tony R.; Piper, P. J.


    Lightweight high efficiency electric motors are needed across a wide range of space applications from - thrust vector actuator control for launch and flight applications to - general vehicle, base camp habitat and experiment control for various mechanisms to - robotics for various stationary and mobile space exploration missions. QM Power?s Parallel Path Magnetic Technology Motors have slowly proven themselves to be a leading motor technology in this area; winning a NASA Phase II for "Lightweight High Efficiency Electric Motors and Actuators for Low Temperature Mobility and Robotics Applications" a US Army Phase II SBIR for "Improved Robot Actuator Motors for Medical Applications", an NSF Phase II SBIR for "Novel Low-Cost Electric Motors for Variable Speed Applications" and a DOE SBIR Phase I for "High Efficiency Commercial Refrigeration Motors" Parallel Path Magnetic Technology obtains the benefits of using permanent magnets while minimizing the historical trade-offs/limitations found in conventional permanent magnet designs. The resulting devices are smaller, lower weight, lower cost and have higher efficiency than competitive permanent magnet and non-permanent magnet designs. QM Power?s motors have been extensively tested and successfully validated by multiple commercial and aerospace customers and partners as Boeing Research and Technology. Prototypes have been made between 0.1 and 10 HP. They are also in the process of scaling motors to over 100kW with their development partners. In this paper, Parallel Path Magnetic Technology Motors will be discussed; specifically addressing their higher efficiency, higher power density, lighter weight, smaller physical size, higher low end torque, wider power zone, cooler temperatures, and greater reliability with lower cost and significant environment benefit for the same peak output power compared to typically motors. A further discussion on the inherent redundancy of these motors for space applications will be provided.

  13. Highly Efficient Enzymatic Preparation of Daidzein in Deep Eutectic Solvents

    Directory of Open Access Journals (Sweden)

    Qi-Bin Cheng


    Full Text Available Daidzein, which is scarce in nature, has gained significant attention due to its superior biological activity and bioavailability compared with daidzin. So far, it has been widely used in the medicine and health care products industries. The enzymatic approach for the preparation of daidzein has prevailed, benefitted by its high efficiency and eco-friendly nature. Our present research aimed at providing a preparation method of daidzein by enzymatic hydrolysis of daidzin in a new “green” reaction medium-deep eutectic solvents (DESs. Herein, the DESs were screened via evaluating enzyme activity, enzyme stability and the substrate solubility, and the DES (ChCl/EG 2:1, 30 vol % was believed to be the most appropriate co-solvent to improve the bioconversion efficiency. Based on the yield of daidzein, response surface methodology (RSM was employed to model and optimize the reaction parameters. Under these optimum process conditions, the maximum yield of 97.53% was achieved and the purity of daidzein crude product reached more than 70%, which is more efficient than conversions in DESs-free buffer. Importantly, it has been shown that DESs medium could be reused for six batches of the process with a final conversion of above 50%. The results indicated that this procedure could be considered a mild, environmentally friendly, highly efficient approach to the economical production of daidzein, with a simple operation process and without any harmful reagents being involved.

  14. Efficient Smoothed Concomitant Lasso Estimation for High Dimensional Regression (United States)

    Ndiaye, Eugene; Fercoq, Olivier; Gramfort, Alexandre; Leclère, Vincent; Salmon, Joseph


    In high dimensional settings, sparse structures are crucial for efficiency, both in term of memory, computation and performance. It is customary to consider ℓ 1 penalty to enforce sparsity in such scenarios. Sparsity enforcing methods, the Lasso being a canonical example, are popular candidates to address high dimension. For efficiency, they rely on tuning a parameter trading data fitting versus sparsity. For the Lasso theory to hold this tuning parameter should be proportional to the noise level, yet the latter is often unknown in practice. A possible remedy is to jointly optimize over the regression parameter as well as over the noise level. This has been considered under several names in the literature: Scaled-Lasso, Square-root Lasso, Concomitant Lasso estimation for instance, and could be of interest for uncertainty quantification. In this work, after illustrating numerical difficulties for the Concomitant Lasso formulation, we propose a modification we coined Smoothed Concomitant Lasso, aimed at increasing numerical stability. We propose an efficient and accurate solver leading to a computational cost no more expensive than the one for the Lasso. We leverage on standard ingredients behind the success of fast Lasso solvers: a coordinate descent algorithm, combined with safe screening rules to achieve speed efficiency, by eliminating early irrelevant features.

  15. Advanced Klystrons for High Efficiency Accelerator Systems - Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Read, Michael; Ives, Robert Lawrence


    This program explored tailoring of RF pulses used to drive accelerator cavities. Simulations indicated that properly shaping the pulse risetime to match accelerator cavity characteristics reduced reflected power and increased total efficiency. Tailoring the pulse requires a high power, gridded, klystron to shape the risetime while also controlling the beam current. The Phase I program generated a preliminary design of a gridded electron gun for a klystron producing 5-10 MW of RF power. This required design of a segmented cathode using Controlled Porosity Reservoir cathodes to limit power deposition on the grid. The program was successful in computationally designing a gun producing a high quality electron beam with grid control. Additional analysis of pulse tailoring indicated that technique would only be useful for cavity drive pulses that were less than approximately 2-3 times the risetime. Otherwise, the efficiency gained during the risetime of the pulse became insignificant when considering the efficiency over the entire pulse. Consequently, it was determined that a Phase II program would not provide sufficient return to justify the cost. Never the less, other applications for a high power gridded gun are currently being pursued. This klystron, for example, would facilitate development inverse Comptom x-ray sources by providing a high repetition rate (10 -100 kHz) RF source.

  16. High-efficiency nanostructured window GaAs solar cells. (United States)

    Liang, Dong; Kang, Yangsen; Huo, Yijie; Chen, Yusi; Cui, Yi; Harris, James S


    Nanostructures have been widely used in solar cells due to their extraordinary optical properties. In most nanostructured cells, high short circuit current has been obtained due to enhanced light absorption. However, most of them suffer from lowered open circuit voltage and fill factor. One of the main challenges is formation of good junction and electrical contact. In particular, nanostructures in GaAs only have shown unsatisfactory performances (below 5% in energy conversion efficiency) which cannot match their ideal material properties and the record photovoltaic performances in industry. Here we demonstrate a completely new design for nanostructured solar cells that combines nanostructured window layer, metal mesa bar contact with small area, high quality planar junction. In this way, we not only keep the advanced optical properties of nanostructures such as broadband and wide angle antireflection, but also minimize its negative impact on electrical properties. High light absorption, efficient carrier collection, leakage elimination, and good lateral conductance can be simultaneously obtained. A nanostructured window cell using GaAs junction and AlGaAs nanocone window demonstrates 17% energy conversion efficiency and 0.982 V high open circuit voltage.

  17. A critical study of high efficiency deep grinding

    CERN Document Server

    Johnstone, I


    The recent years, the aerospace industry in particular has embraced and actively pursued the development of stronger high performance materials, namely nickel based superalloys and hardwearing steels. This has resulted in a need for a more efficient method of machining, and this need was answered with the advent of High Efficiency Deep Grinding (HEDG). This relatively new process using Cubic Boron Nitride (CBN) electroplated grinding wheels has been investigated through experimental and theoretical means applied to two widely used materials, M50 bearing steel and IN718 nickel based superalloy. It has been shown that this grinding method using a stiff grinding centre such as the Edgetek 5-axis machine is a viable process. Using a number of experimental designs, produced results which were analysed using a variety of methods including visual assessment, sub-surface microscopy and surface analysis using a Scanning Electron Microscope (SEM), residual stress measurement using X-Ray Diffraction (XRD) techniques, Ba...

  18. High resolution PET breast imager with improved detection efficiency (United States)

    Majewski, Stanislaw


    A highly efficient PET breast imager for detecting lesions in the entire breast including those located close to the patient's chest wall. The breast imager includes a ring of imaging modules surrounding the imaged breast. Each imaging module includes a slant imaging light guide inserted between a gamma radiation sensor and a photodetector. The slant light guide permits the gamma radiation sensors to be placed in close proximity to the skin of the chest wall thereby extending the sensitive region of the imager to the base of the breast. Several types of photodetectors are proposed for use in the detector modules, with compact silicon photomultipliers as the preferred choice, due to its high compactness. The geometry of the detector heads and the arrangement of the detector ring significantly reduce dead regions thereby improving detection efficiency for lesions located close to the chest wall.

  19. Fusion blanket for high-efficiency power cycles

    Energy Technology Data Exchange (ETDEWEB)

    Usher, J.L.; Powell, J.R.; Fillo, J.A.; Horn, F.L.; Lazareth, O.W.; Taussig, R.


    The efficiencies of blankets for fusion reactors are usually in the range of 30 to 40%, limited by the operating temperature (500/sup 0/C) of conventional structural materials such as stainless steels. In this project two-zone blankets are proposed; these blankets consist of a low-temperature shell surrounding a high-temperature interior zone. A survey of nucleonics and thermal hydraulic parameters has led to a reference blanket design consisting of a water-cooled stainless steel shell around a BeO, ZrO/sub 2/ interior (cooled by Ar) utilizing Li/sub 2/O for tritium breeding. In this design, approx. 60% of the fusion energy is deposited in the high-temperature interior. The maximum Ar temperature is 2230/sup 0/C leading to an overall efficiency estimate of 55 to 60% for this reference case.

  20. A high efficiency cloning and expression system for proteomic analysis. (United States)

    Ding, Xuan Z; Paulsen, Ian T; Bhattacharjee, Apurba K; Nikolich, Mikeljon P; Myers, Gary; Hoover, David L


    The recent description of the complete genomes of the two most pathogenic species of Brucella opens the way for genome-based analysis of the antigenicity of their proteins. In the present report, we describe a bench-level high-efficiency cloning and expression system (HECES) that allow expression of large numbers of Brucella proteins based on genomic sequence information. Purified proteins are produced with high efficiency in a microarray format conducive to analysis of their sero-reactivity against serum from immunized animals. This method is applicable at either small or large scale of protein processing. While it does not require robotics, the format is amenable to robotic implementation for all aspects of the process and subsequent analysis of protein characteristics. This method will allow selection of new reagents for diagnosis of brucellosis and development of vaccine against Brucella, an important zoonotic disease and biothreat agent.

  1. Modelling and fabrication of high-efficiency silicon solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Rohatgi, A.; Smith, A.W.; Salami, J. [Georgia Inst. of Tech., Atlanta, GA (United States). School of Electrical Engineering


    This report covers the research conducted on modelling and development of high-efficiency silicon solar cells during the period May 1989 to August 1990. First, considerable effort was devoted toward developing a ray-tracing program for the photovoltaic community to quantify and optimize surface texturing for solar cells. Second, attempts were made to develop a hydrodynamic model for device simulation. Such a model is somewhat slower than drift-diffusion type models like PC-1D, but it can account for more physical phenomena in the device, such as hot carrier effects, temperature gradients, thermal diffusion, and lattice heat flow. In addition, Fermi-Dirac statistics have been incorporated into the model to deal with heavy doping effects more accurately. Third and final component of the research includes development of silicon cell fabrication capabilities and fabrication of high-efficiency silicon cells. 84 refs., 46 figs., 10 tabs.

  2. High-efficiency reconciliation for continuous variable quantum key distribution (United States)

    Bai, Zengliang; Yang, Shenshen; Li, Yongmin


    Quantum key distribution (QKD) is the most mature application of quantum information technology. Information reconciliation is a crucial step in QKD and significantly affects the final secret key rates shared between two legitimate parties. We analyze and compare various construction methods of low-density parity-check (LDPC) codes and design high-performance irregular LDPC codes with a block length of 106. Starting from these good codes and exploiting the slice reconciliation technique based on multilevel coding and multistage decoding, we realize high-efficiency Gaussian key reconciliation with efficiency higher than 95% for signal-to-noise ratios above 1. Our demonstrated method can be readily applied in continuous variable QKD.

  3. Wavy channel transistor for area efficient high performance operation

    KAUST Repository

    Fahad, Hossain M.


    We report a wavy channel FinFET like transistor where the channel is wavy to increase its width without any area penalty and thereby increasing its drive current. Through simulation and experiments, we show the effectiveness of such device architecture is capable of high performance operation compared to conventional FinFETs with comparatively higher area efficiency and lower chip latency as well as lower power consumption.

  4. High-efficiency pumps drastically reduce energy consumption

    Energy Technology Data Exchange (ETDEWEB)



    Wilo's Stratos pumps for air conditioning and other domestic heating applications combine the advantages of wet runner technology with an innovative electronic commutator motor. The energy consumption of these high-efficiency pumps is halved compared with similar wet runner designs. With vast numbers of pumps used in buildings across Europe alone, the adoption of this technology potentially offers significant energy sayings. (Author)

  5. High-efficient search and analysis of road signs

    Directory of Open Access Journals (Sweden)

    Дмитрий Александрович Морозов


    Full Text Available It is developed high-efficient algorithm for search and analysis of road signs. The work is based on the results of reviewing existing sources which describe given problem. There are described the most common steps in algorithm logic. There is designed, implemented and tested special program, which works on given algorithm. The results of testing show good recognition quality. Such program can be used as a part of driver assistance systems

  6. A New Envelope with Highly Energy-Efficient Insulation


    Alonso Pastor, Luis Alberto; Lauret Aguirregabiria, Benito; Alonso Amo, Fernando


    This article examines, from the insulation viewpoint, a new lightweight, slim, high energy efficient, lighttransmitting envelope system, providing for seamless, free-form designs for use in architectural projects. The research was based on envelope components already existing on the market, especially components implemented with granular silica gel insulation, as this is the most effective translucent thermal insulation there is today. The tests run on these materials revealed tha...

  7. Highly efficient electron vortex beams generated by nanofabricated phase holograms

    Energy Technology Data Exchange (ETDEWEB)

    Grillo, Vincenzo, E-mail: [CNR-Istituto Nanoscienze, Centro S3, Via G Campi 213/a, I-41125 Modena (Italy); CNR-IMEM Parco Area delle Scienze 37/A, I-43124 Parma (Italy); Carlo Gazzadi, Gian [CNR-Istituto Nanoscienze, Centro S3, Via G Campi 213/a, I-41125 Modena (Italy); Karimi, Ebrahim [CNR-Istituto Nanoscienze, Centro S3, Via G Campi 213/a, I-41125 Modena (Italy); Department of Physics, University of Ottawa, 150 Louis Pasteur, Ottawa, Ontario K1N 6N5 (Canada); Mafakheri, Erfan [Dipartimento di Fisica Informatica e Matematica, Università di Modena e Reggio Emilia, via G Campi 213/a, I-41125 Modena (Italy); Boyd, Robert W. [Department of Physics, University of Ottawa, 150 Louis Pasteur, Ottawa, Ontario K1N 6N5 (Canada); Frabboni, Stefano [CNR-Istituto Nanoscienze, Centro S3, Via G Campi 213/a, I-41125 Modena (Italy); Dipartimento di Fisica Informatica e Matematica, Università di Modena e Reggio Emilia, via G Campi 213/a, I-41125 Modena (Italy)


    We propose an improved type of holographic-plate suitable for the shaping of electron beams. The plate is fabricated by a focused ion beam on a silicon nitride membrane and introduces a controllable phase shift to the electron wavefunction. We adopted the optimal blazed-profile design for the phase hologram, which results in the generation of highly efficient (25%) electron vortex beams. This approach paves the route towards applications in nano-scale imaging and materials science.

  8. Outdoor Characterisation of High Efficiency Luminescent Solar Concentrators


    PRAVETTONI Mauro; VIRTUANI Alessandro; Kenny, Robert; Daniel J. Farrell; Chatten, Amanda J.; Barnham, Keith W J


    This work presents recent results on outdoor characterisation of high efficiency luminescent solar concentrators. Outdoor measurements at 25°C and corrected to 1000 W/m2 have been compared with indoor characterization according to the international standards for conventional photovoltaic devices. Dependence of electrical parameters with temperature is also shown, together with results of various 1-day monitoring campaigns of luminescent concentrators performance under varying irradiance condi...

  9. Surface nanodroplets for highly efficient liquid-liquid microextraction (United States)

    Li, Miaosi; Lu, Ziyang; Yu, Haitao; Zhang, Xuehua


    Nanoscale droplets on a substrate are an essential element for a wide range of applications, such as laboratory-on-chip devices, simple and highly efficient miniaturized reactors for concentrating products, high-throughput single-bacteria or single-biomolecular analysis, encapsulation, and high-resolution imaging techniques. The solvent exchange process is a simple bottom-up approach for producing droplets at solid-liquid interfaces that are only several tens to hundreds of nanometers in height, or a few femtoliters in volume Oil nanodroplets can be produced on a substrate by solvent exchange in which a good solvent of oil is displaced by a poor solvent. Our previous work has significantly advanced understanding of the principle of solvent exchange, and the droplet size can be well-controlled by several parameters, including flow rates, flow geometry, gravitational effect and composition of solutions. In this work, we studied the microextraction effect of surface nanodroplets. Oil nanodroplets have been demonstrated to provide highly-efficient liquid-liquid microextraction of hydrophobic solute in a highly diluted solution. This effect proved the feasibility of nanodroplets as a platform for preconcentrating compounds for in situ highly sensitive microanalysis without further separation. Also the long lifetime and temporal stability of surface nanodroplets allow for some long-term extraction process and extraction without addition of stabilisers.

  10. High-efficiency, broad band, high-damage threshold high-index gratings for femtosecond pulse compression. (United States)

    Canova, Frederico; Clady, Raphael; Chambaret, Jean-Paul; Flury, Manuel; Tonchev, Svtelen; Fechner, Renate; Parriaux, Olivier


    High efficiency, broad-band TE-polarization diffraction over a wavelength range centered at 800 nm is obtained by high index gratings placed on a non-corrugated mirror. More than 96% efficiency wide band top-hat diffraction efficiency spectra, as well as more than 1 J/cm(2) damage threshold under 50 fs pulses are demonstrated experimentally. This opens the way to high-efficiency Chirped Pulse Amplification for high average power laser machining by means of all-dielectric structures as well as for ultra-short high energy pulses by means of metal-dielectric structures.

  11. Efficiency of nonstandard and high contact ratio involute spur gears (United States)

    Anderson, N. E.; Loewenthal, S. H.


    A power loss prediction was extended to include involute spur gears of nonstandard proportions. The method is used to analyze the effects of modified addendum, tooth thickness, and gear center distance in addition to the parameters previously considered which included gear diameter, pitch, pressure angle, face width, oil viscosity, speed, and torque. Particular emphasis was placed on high contact ratio gearing (contact ratios greater than two). Despite their higher sliding velocities, high contact ratio gears are designed to levels of efficiency comparable to those of conventional gears while retaining their advantages through proper selection of gear geometry.

  12. Testing the efficiency of high-frequency foreign exchange market

    Directory of Open Access Journals (Sweden)

    Václav Mastný


    Full Text Available This paper deals with the efficiency of the high-frequency foreign exchange market. The objective of this paper is to investigate whether standard statistical tests give the same results for time series resampled at intervals of 15.30 and 60 min. The data used for the purpose of this paper contain major currency pairs such as EUR/USD, GBP/USD and JPY/USD. The results of statistical tests indicate that the high frequency intervals (15-minute are not random and should not be considered independent. On the other hand, tests with lower frequency rates (30 and 60 min indicate rising randomness of the market.

  13. Study of High-Efficiency Motors Using Soft Magnetic Cores (United States)

    Tokoi, Hirooki; Kawamata, Shoichi; Enomoto, Yuji

    We have been developed a small and highly efficient axial gap motor whose stator core is made of a soft magnetic core. First, the loss sensitivities to various motor design parameters were evaluated using magnetic field analysis. It was found that the pole number and core dimensions had low sensitivity (≤ 2.2dB) in terms of the total loss, which is the sum of the copper loss and the iron losses in the stator core and the rotor yoke respectively. From this, we concluded that to improve the motor efficiency, it is essential to reduce the iron loss in the rotor yoke and minimize other losses. With this in mind, a prototype axial gap motor is manufactured and tested. The motor has four poles and six slots. The motor is 123mm in diameter and the axial length is 47mm. The rotor has parallel magnetized magnets and a rotor yoke with magnetic steel sheets. The maximum measured motor efficiency is 93%. This value roughly agrees with the maximum calculated efficiency of 95%.

  14. High Efficiency CVD Graphene-lead (Pb) Cooper Pair Splitter. (United States)

    Borzenets, I V; Shimazaki, Y; Jones, G F; Craciun, M F; Russo, S; Yamamoto, M; Tarucha, S


    Generation and manipulation of quantum entangled electrons is an important concept in quantum mechanics, and necessary for advances in quantum information processing; but not yet established in solid state systems. A promising device is a superconductor-two quantum dots Cooper pair splitter. Early nanowire based devices, while efficient, are limited in scalability and further electron manipulation. We demonstrate an optimized, high efficiency, CVD grown graphene-based Cooper pair splitter. Our device is designed to induce superconductivity in graphene via the proximity effect, resulting in both a large superconducting gap Δ = 0.5 meV, and coherence length ξ = 200 nm. The flat nature of the device lowers parasitic capacitance, increasing charging energy EC. Our design also eases geometric restrictions and minimizes output channel separation. As a result we measure a visibility of up to 86% and a splitting efficiency of up to 62%. This will pave the way towards near unity efficiencies, long distance splitting, and post-splitting electron manipulation.

  15. High Efficiency Heat Exchanger for High Temperature and High Pressure Applications

    Energy Technology Data Exchange (ETDEWEB)

    Sienicki, James J. [Argonne National Lab. (ANL), Argonne, IL (United States). Nuclear Engineering Division; Lv, Qiuping [Argonne National Lab. (ANL), Argonne, IL (United States). Nuclear Engineering Division; Moisseytsev, Anton [Argonne National Lab. (ANL), Argonne, IL (United States). Nuclear Engineering Division


    CompRex, LLC (CompRex) specializes in the design and manufacture of compact heat exchangers and heat exchange reactors for high temperature and high pressure applications. CompRex’s proprietary compact technology not only increases heat exchange efficiency by at least 25 % but also reduces footprint by at least a factor of ten compared to traditional shell-and-tube solutions of the same capacity and by 15 to 20 % compared to other currently available Printed Circuit Heat Exchanger (PCHE) solutions. As a result, CompRex’s solution is especially suitable for Brayton cycle supercritical carbon dioxide (sCO2) systems given its high efficiency and significantly lower capital and operating expenses. CompRex has already successfully demonstrated its technology and ability to deliver with a pilot-scale compact heat exchanger that was under contract by the Naval Nuclear Laboratory for sCO2 power cycle development. The performance tested unit met or exceeded the thermal and hydraulic specifications with measured heat transfer between 95 to 98 % of maximum heat transfer and temperature and pressure drop values all consistent with the modeled values. CompRex’s vision is to commercialize its compact technology and become the leading provider for compact heat exchangers and heat exchange reactors for various applications including Brayton cycle sCO2 systems. One of the limitations of the sCO2 Brayton power cycle is the design and manufacturing of efficient heat exchangers at extreme operating conditions. Current diffusion-bonded heat exchangers have limitations on the channel size through which the fluid travels, resulting in excessive solid material per heat exchanger volume. CompRex’s design allows for more open area and shorter fluid proximity for increased heat transfer efficiency while sustaining the structural integrity needed for the application. CompRex is developing a novel improvement to its current heat exchanger design where fluids are directed to alternating

  16. Highly Efficient Thermoresponsive Nanocomposite for Controlled Release Applications

    KAUST Repository

    Yassine, Omar


    Highly efficient magnetic release from nanocomposite microparticles is shown, which are made of Poly (N-isopropylacrylamide) hydrogel with embedded iron nanowires. A simple microfluidic technique was adopted to fabricate the microparticles with a high control of the nanowire concentration and in a relatively short time compared to chemical synthesis methods. The thermoresponsive microparticles were used for the remotely triggered release of Rhodamine (B). With a magnetic field of only 1 mT and 20 kHz a drug release of 6.5% and 70% was achieved in the continuous and pulsatile modes, respectively. Those release values are similar to the ones commonly obtained using superparamagnetic beads but accomplished with a magnetic field of five orders of magnitude lower power. The high efficiency is a result of the high remanent magnetization of the nanowires, which produce a large torque when exposed to a magnetic field. This causes the nanowires to vibrate, resulting in friction losses and heating. For comparison, microparticles with superparamagnetic beads were also fabricated and tested; while those worked at 73 mT and 600 kHz, no release was observed at the low field conditions. Cytotoxicity assays showed similar and high cell viability for microparticles with nanowires and beads.

  17. The influence of ENSO, PDO and PNA on secular rainfall variations in Hawai`i (United States)

    Frazier, Abby G.; Elison Timm, Oliver; Giambelluca, Thomas W.; Diaz, Henry F.


    Over the last century, significant declines in rainfall across the state of Hawai`i have been observed, and it is unknown whether these declines are due to natural variations in climate, or manifestations of human-induced climate change. Here, a statistical analysis of the observed rainfall variability was applied as first step towards better understanding causes for these long-term trends. Gridded seasonal rainfall from 1920 to 2012 is used to perform an empirical orthogonal function (EOF) analysis. The leading EOF components are correlated with three indices of natural climate variations (El Niño-Southern Oscillation (ENSO), Pacific Decadal Oscillation (PDO), and Pacific North American (PNA)), and multiple linear regression (MLR) is used to model the leading components with climate indices. PNA is the dominant mode of wet season (November-April) variability, while ENSO is most significant in the dry season (May-October). To assess whether there is an anthropogenic influence on rainfall, two methods are used: a linear trend term is included in the MLR, and pattern correlation coefficients (PCC) are calculated between recent rainfall trends and future changes in rainfall projected by downscaling methods. PCC results indicate that recent observed rainfall trends in the wet season are positively correlated with future expected changes in rainfall, while dry season PCC results do not show a clear pattern. The MLR results, however, show that the trend term adds significantly to model skill only in the dry season. Overall, MLR and PCC results give weak and inconclusive evidence for detection of anthropogenic signals in the observed rainfall trends.

  18. A high efficiency hybrid stirling-pulse tube cryocooler

    Directory of Open Access Journals (Sweden)

    Xiaotao Wang


    Full Text Available This article presented a hybrid cryocooler which combines the room temperature displacers and the pulse tube in one system. Compared with a traditional pulse tube cryocooler, the system uses the rod-less ambient displacer to recover the expansion work from the pulse tube cold end to improve the efficiency while still keeps the advantage of the pulse tube cryocooler with no moving parts at the cold region. In the meantime, dual-opposed configurations for both the compression pistons and displacers reduce the cooler vibration to a very low level. In the experiments, a lowest no-load temperature of 38.5 K has been obtained and the cooling power at 80K was 26.4 W with an input electric power of 290 W. This leads to an efficiency of 24.2% of Carnot, marginally higher than that of an ordinary pulse tube cryocooler. The hybrid configuration herein provides a very competitive option when a high efficiency, high-reliability and robust cryocooler is desired.

  19. High-Efficiency Hall Thruster Discharge Power Converter (United States)

    Jaquish, Thomas


    Busek Company, Inc., is designing, building, and testing a new printed circuit board converter. The new converter consists of two series or parallel boards (slices) intended to power a high-voltage Hall accelerator (HiVHAC) thruster or other similarly sized electric propulsion devices. The converter accepts 80- to 160-V input and generates 200- to 700-V isolated output while delivering continually adjustable 300-W to 3.5-kW power. Busek built and demonstrated one board that achieved nearly 94 percent efficiency the first time it was turned on, with projected efficiency exceeding 97 percent following timing software optimization. The board has a projected specific mass of 1.2 kg/kW, achieved through high-frequency switching. In Phase II, Busek optimized to exceed 97 percent efficiency and built a second prototype in a form factor more appropriate for flight. This converter then was integrated with a set of upgraded existing boards for powering magnets and the cathode. The program culminated with integrating the entire power processing unit and testing it on a Busek thruster and on NASA's HiVHAC thruster.

  20. High-efficiency Commercial Cold Climate Heat Pump

    Energy Technology Data Exchange (ETDEWEB)

    Mahmoud, Ahmad M. [United Technologies Research Center, East Hartford, CT (United States); Cogswell, F. [United Technologies Research Center, East Hartford, CT (United States); Verma, P. [United Technologies Research Center, East Hartford, CT (United States)


    United Technologies Research Center (UTRC) proposed in 2012 to design, develop and demonstrate an air-source 10TR high-efficiency commercial cold climate heat pump (CCCHP). The proposed heat pump would be scalable beyond 40TR, cost effective with a simple payback of < 3 years upon commercialization and would reduce annual electricity use for building space heating in cold climates by at least 20%. This would represent an annual savings of $2.3 billion and a 20% displacement of total greenhouse gases generated upon full commercialization. The primary objective was to develop a highly integrated system that shall meet or exceed DOE capacity and efficiency targets at key conditions and is scalable, cost-effective and simple relative to the state-of-the-art. Specifically, the goal of the project was to design, develop and demonstrate a CCCHP that exceeds DOE capacity degradation requirements at +17F and -13F conditions (0 and <15% degradation vs. 10 and 25% DOE requirements, respectively) while meeting or exceeding DOE capacity and system efficiency requirements at all other conditions.

  1. Highly Efficient Inverted Structural Quantum Dot Solar Cells. (United States)

    Wang, Ruili; Wu, Xun; Xu, Kaimin; Zhou, Wenjia; Shang, Yuequn; Tang, Haoying; Chen, Hao; Ning, Zhijun


    Highly efficient PbS colloidal quantum dot (QD) solar cells based on an inverted structure have been missing for a long time. The bottlenecks are the construction of an effective p-n heterojunction at the illumination side with smooth band alignment and the absence of serious interface carrier recombination. Here, solution-processed nickel oxide (NiO) as the p-type layer and lead sulfide (PbS) QDs with iodide ligand as the n-type layer are explored to build a p-n heterojunction at the illumination side. The large depletion region in the QD layer at the illumination side leads to high photocurrent. Interface carrier recombination at the interface is effectively prohibited by inserting a layer of slightly doped p-type QDs with 1,2-ethanedithiol as ligands, leading to improved voltage of the device. Based on this graded device structure design, the efficiency of inverted structural heterojunction PbS QD solar cells is improved to 9.7%, one time higher than the highest efficiency achieved before. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. High-efficiency ballistic electrostatic generator using microdroplets (United States)

    Xie, Yanbo; Bos, Diederik; de Vreede, Lennart J.; de Boer, Hans L.; van der Meulen, Mark-Jan; Versluis, Michel; Sprenkels, Ad J.; van den Berg, Albert; Eijkel, Jan C. T.


    The strong demand for renewable energy promotes research on novel methods and technologies for energy conversion. Microfluidic systems for energy conversion by streaming current are less known to the public, and the relatively low efficiencies previously obtained seemed to limit the further applications of such systems. Here we report a microdroplet-based electrostatic generator operating by an acceleration-deceleration cycle (‘ballistic’ conversion), and show that this principle enables both high efficiency and compact simple design. Water is accelerated by pumping it through a micropore to form a microjet breaking up into fast-moving charged droplets. Droplet kinetic energy is converted to electrical energy when the charged droplets decelerate in the electrical field that forms between membrane and target. We demonstrate conversion efficiencies of up to 48%, a power density of 160 kW m-2 and both high- (20 kV) and low- (500 V) voltage operation. Besides offering striking new insights, the device potentially opens up new perspectives for low-cost and robust renewable energy conversion.

  3. Design Strategies for Ultra-high Efficiency Photovoltaics (United States)

    Warmann, Emily Cathryn

    While concentrator photovoltaic cells have shown significant improvements in efficiency in the past ten years, once these cells are integrated into concentrating optics, connected to a power conditioning system and deployed in the field, the overall module efficiency drops to only 34 to 36%. This efficiency is impressive compared to conventional flat plate modules, but it is far short of the theoretical limits for solar energy conversion. Designing a system capable of achieving ultra high efficiency of 50% or greater cannot be achieved by refinement and iteration of current design approaches. This thesis takes a systems approach to designing a photovoltaic system capable of 50% efficient performance using conventional diode-based solar cells. The effort began with an exploration of the limiting efficiency of spectrum splitting ensembles with 2 to 20 sub cells in different electrical configurations. Incorporating realistic non-ideal performance with the computationally simple detailed balance approach resulted in practical limits that are useful to identify specific cell performance requirements. This effort quantified the relative benefit of additional cells and concentration for system efficiency, which will help in designing practical optical systems. Efforts to improve the quality of the solar cells themselves focused on the development of tunable lattice constant epitaxial templates. Initially intended to enable lattice matched multijunction solar cells, these templates would enable increased flexibility in band gap selection for spectrum splitting ensembles and enhanced radiative quality relative to metamorphic growth. The III-V material family is commonly used for multijunction solar cells both for its high radiative quality and for the ease of integrating multiple band gaps into one monolithic growth. The band gap flexibility is limited by the lattice constant of available growth templates. The virtual substrate consists of a thin III-V film with the desired

  4. Chemical reaction interface mass spectrometry with high efficiency nebulization. (United States)

    Jorabchi, Kaveh; Kahen, Kaveh; Lecchi, Paolo; Montaser, Akbar


    A high efficiency nebulizer (HEN) coupled to a heated spray chamber and a membrane desolvator is used for liquid sample introduction in chemical reaction interface mass spectrometry (CRIMS). Compared to the conventional thermospray nebulizer operated at solvent flow rate of 1 mL/min, the HEN provides small droplets at lower flow rates (10-100 microL/min), improving the desolvation and analyte transport efficiency. As a result, the sensitivity for carbon detection by CRIMS is improved by a factor of 4. The new arrangement offers an easy-to-use and robust interface, facilitating the availability of a variety of liquid chromatographic techniques to the CRIMS. Separation and detection of labeled peptides in a mixture of unlabeled biopolymers is illustrated at a solvent flow rate of 45 microL/min as an example of new possibilities offered by the improved liquid introduction interface.

  5. High Efficient Universal Buck Boost Solar Array Regulator SAR Module (United States)

    Kimmelmann, Stefan; Knorr, Wolfgang


    The high efficient universal Buck Boost Solar Array Regulator (SAR) module concept is applicable for a wide range of input and output voltages. The single point failure tolerant SAR module contains 3 power converters for the transfer of the SAR power to the battery dominated power bus. The converters are operating parallel in a 2 out of 3 redundancy and are driven by two different controllers. The output power of one module can be adjusted up to 1KW depending on the requirements. The maximum power point tracker (MPPT) is placed on a separate small printed circuit board and can be used if no external tracker signal is delivered. Depending on the mode and load conditions an efficiency of more than 97% is achievable. The stable control performance is achieved by implementing the magnetic current sense detection. The sensed power coil current is used in Buck and Boost control mode.

  6. Efficient high-quality volume rendering of SPH data. (United States)

    Fraedrich, Roland; Auer, Stefan; Westermann, Rüdiger


    High quality volume rendering of SPH data requires a complex order-dependent resampling of particle quantities along the view rays. In this paper we present an efficient approach to perform this task using a novel view-space discretization of the simulation domain. Our method draws upon recent work on GPU-based particle voxelization for the efficient resampling of particles into uniform grids. We propose a new technique that leverages a perspective grid to adaptively discretize the view-volume, giving rise to a continuous level-of-detail sampling structure and reducing memory requirements compared to a uniform grid. In combination with a level-of-detail representation of the particle set, the perspective grid allows effectively reducing the amount of primitives to be processed at run-time. We demonstrate the quality and performance of our method for the rendering of fluid and gas dynamics SPH simulations consisting of many millions of particles.

  7. Development of a high efficiency, automatic defrosting refrigerator-freezer (United States)

    Topping, R. F.; Lee, W. D.

    The development of an energy efficient refrigerator freezer prototype to accelerate the commercialization of residential, high efficiency refrigerator freezers is described. A computer model developed to simulate the cabinet and refrigeration unit performance was used to evaluate alternative designs and optimize the cabinet insulation as well as the refrigeration component integration. Placement of polyurethane foam insulation in the cabinet and thicker insulation in the doors were used to reduce the closed door heat load of the prototype. Modifications to the evaporator system provide automatic frost-free operation with a significantly reduced defrost energy requirement. Resulting higher moisture levels in the refrigerator compartment enhance fresh food storage. A dual control system, different from most models which use only one active control, provides precise temperature regulation in both the freezer and refrigerator compartments.

  8. Efficient biprediction decision scheme for fast high efficiency video coding encoding (United States)

    Park, Sang-hyo; Lee, Seung-ho; Jang, Euee S.; Jun, Dongsan; Kang, Jung-Won


    An efficient biprediction decision scheme of high efficiency video coding (HEVC) is proposed for fast-encoding applications. For low-delay video applications, bidirectional prediction can be used to increase compression performance efficiently with previous reference frames. However, at the same time, the computational complexity of the HEVC encoder is significantly increased due to the additional biprediction search. Although a some research has attempted to reduce this complexity, whether the prediction is strongly related to both motion complexity and prediction modes in a coding unit has not yet been investigated. A method that avoids most compression-inefficient search points is proposed so that the computational complexity of the motion estimation process can be dramatically decreased. To determine if biprediction is critical, the proposed method exploits the stochastic correlation of the context of prediction units (PUs): the direction of a PU and the accuracy of a motion vector. Through experimental results, the proposed method showed that the time complexity of biprediction can be reduced to 30% on average, outperforming existing methods in view of encoding time, number of function calls, and memory access.

  9. Efficient temporal and interlayer parameter prediction for weighted prediction in scalable high efficiency video coding (United States)

    Tsang, Sik-Ho; Chan, Yui-Lam; Siu, Wan-Chi


    Weighted prediction (WP) is an efficient video coding tool that was introduced since the establishment of the H.264/AVC video coding standard, for compensating the temporal illumination change in motion estimation and compensation. WP parameters, including a multiplicative weight and an additive offset for each reference frame, are required to be estimated and transmitted to the decoder by slice header. These parameters cause extra bits in the coded video bitstream. High efficiency video coding (HEVC) provides WP parameter prediction to reduce the overhead. Therefore, WP parameter prediction is crucial to research works or applications, which are related to WP. Prior art has been suggested to further improve the WP parameter prediction by implicit prediction of image characteristics and derivation of parameters. By exploiting both temporal and interlayer redundancies, we propose three WP parameter prediction algorithms, enhanced implicit WP parameter, enhanced direct WP parameter derivation, and interlayer WP parameter, to further improve the coding efficiency of HEVC. Results show that our proposed algorithms can achieve up to 5.83% and 5.23% bitrate reduction compared to the conventional scalable HEVC in the base layer for SNR scalability and 2× spatial scalability, respectively.

  10. Tunable C2N Membrane for High Efficient Water Desalination (United States)

    Yang, Yanmei; Li, Weifeng; Zhou, Hongcai; Zhang, Xiaoming; Zhao, Mingwen


    Water scarcity represents one of the most serious global problems of our time and challenges the advancements in desalination techniques. Although water-filtering architectures based on graphene have greatly advanced the approach to high performance desalination membranes, the controlled-generation of nanopores with particular diameter is tricky and has stunted its wide applications. Here, through molecular dynamic simulations and first-principles calculations, we propose that the recently reported graphene-like carbon nitride (g-C2N) monolayer can serve as high efficient filters for water desalination. Taking the advantages of the intrisic nanoporous structure and excellent mechanical properties of g-C2N, high water transparency and strong salt filtering capability have been demonstrated in our simulations. More importantly, the “open” and “closed” states of the g-C2N filter can be precisely regulated by tensile strain. It is found that the water permeability of g-C2N is significantly higher than that reported for graphene filters by almost one order of magnitude. In the light of the abundant family of graphene-like carbon nitride monolayered materials, our results thus offer a promising approach to the design of high efficient filteration architectures. PMID:27384666

  11. Approaches to achieve high grain yield and high resource use efficiency in rice

    Directory of Open Access Journals (Sweden)

    Jianchang YANG


    Full Text Available This article discusses approaches to simultaneously increase grain yield and resource use efficiency in rice. Breeding nitrogen efficient cultivars without sacrificing rice yield potential, improving grain fill in later-flowering inferior spikelets and enhancing harvest index are three important approaches to achieving the dual goal of high grain yield and high resource use efficiency. Deeper root distribution and higher leaf photosynthetic N use efficiency at lower N rates could be used as selection criteria to develop N-efficient cultivars. Enhancing sink activity through increasing sugar-spikelet ratio at the heading time and enhancing the conversion efficiency from sucrose to starch though increasing the ratio of abscisic acid to ethylene in grains during grain fill could effectively improve grain fill in inferior spikelets. Several practices, such as post-anthesis controlled soil drying, an alternate wetting and moderate soil drying regime during the whole growing season, and non-flooded straw mulching cultivation, could substantially increase grain yield and water use efficiency, mainly via enhanced remobilization of stored carbon from vegetative tissues to grains and improved harvest index. Further research is needed to understand synergistic interaction between water and N on crop and soil and the mechanism underlying high resource use efficiency in high-yielding rice.

  12. Highly efficient transfection of human THP-1 macrophages by nucleofection. (United States)

    Maeß, Marten B; Wittig, Berith; Lorkowski, Stefan


    Macrophages, as key players of the innate immune response, are at the focus of research dealing with tissue homeostasis or various pathologies. Transfection with siRNA and plasmid DNA is an efficient tool for studying their function, but transfection of macrophages is not a trivial matter. Although many different approaches for transfection of eukaryotic cells are available, only few allow reliable and efficient transfection of macrophages, but reduced cell vitality and severely altered cell behavior like diminished capability for differentiation or polarization are frequently observed. Therefore a transfection protocol is required that is capable of transferring siRNA and plasmid DNA into macrophages without causing serious side-effects thus allowing the investigation of the effect of the siRNA or plasmid in the context of normal cell behavior. The protocol presented here provides a method for reliably and efficiently transfecting human THP-1 macrophages and monocytes with high cell vitality, high transfection efficiency, and minimal effects on cell behavior. This approach is based on Nucleofection and the protocol has been optimized to maintain maximum capability for cell activation after transfection. The protocol is adequate for adherent cells after detachment as well as cells in suspension, and can be used for small to medium sample numbers. Thus, the method presented is useful for investigating gene regulatory effects during macrophage differentiation and polarization. Apart from presenting results characterizing macrophages transfected according to this protocol in comparison to an alternative chemical method, the impact of cell culture medium selection after transfection on cell behavior is also discussed. The presented data indicate the importance of validating the selection for different experimental settings.

  13. High-efficiency multilayer-dielectric diffraction gratings

    Energy Technology Data Exchange (ETDEWEB)

    Perry, M.D.; Boyd, R.D.; Britten, J.A.


    The ability to produce short laser pulses of extremely high power and high irradiance, as is needed for fast ignitor research in inertial confinement fusion, places increasing demands on optical components such as amplifiers, lenses, and mirrors that must remain undamaged by the radiation. The higher refractive index in the center of an intense laser beam acts as a focusing lens. The resulting wavefront distortion, left uncorrected, eventually leads to catastrophic filamentation. Major advances in energy extraction and resulting increases in focused irradiance have been made possible by the use of chirped-pulse amplification (CPA), long used in radar applications and newly applied to optical frequencies. Optical-frequency CPA systems begin with a mode-locked oscillator that produces low-energy seed pulses with durations of ten to a few hundred femtoseconds. As a result of the classical uncertainty relation between time and frequency, these short pulses have a very broad frequency distribution. A pair of diffraction gratings (or other dispersive elements) lengthens the laser pulse and induces a time-varying frequency (or chirp). Following amplification, diffraction gratings compress the pulse back to nearly the original duration. Typically a nanojoule, femtosecond pulse is stretched by a factor of several thousand and is amplified by as much as 12 orders of magnitude before recompression. By producing the short pulse only after amplification, this technique makes possible efficient extraction of energy from a variety of broadband solid state materials. Achieving high focused irradiance from a pulse ultimately requires both high peak power and excellent beam quality. There is therefore a demand for diffraction gratings that produce a high-quality diffracted wavefront, have high diffraction efficiency, and exhibit a high threshold for laser damage.

  14. Photoconductive Cathode Interlayer for Highly Efficient Inverted Polymer Solar Cells. (United States)

    Nian, Li; Zhang, Wenqiang; Zhu, Na; Liu, Linlin; Xie, Zengqi; Wu, Hongbin; Würthner, Frank; Ma, Yuguang


    A highly photoconductive cathode interlayer was achieved by doping a 1 wt % light absorber, such as perylene bisimide, into a ZnO thin film, which absorbs a very small amount of light but shows highly increased conductivity of 4.50 × 10(-3) S/m under sunlight. Photovoltaic devices based on this kind of photoactive cathode interlayer exhibit significantly improved device performance, which is rather insensitive to the thickness of the cathode interlayer over a broad range. Moreover, a power conversion efficiency as high as 10.5% was obtained by incorporation of our photoconductive cathode interlayer with the PTB7-Th:PC71BM active layer, which is one of the best results for single-junction polymer solar cells.

  15. High efficiency Raman memory by suppressing radiation trapping (United States)

    Thomas, S. E.; Munns, J. H. D.; Kaczmarek, K. T.; Qiu, C.; Brecht, B.; Feizpour, A.; Ledingham, P. M.; Walmsley, I. A.; Nunn, J.; Saunders, D. J.


    Raman interactions in alkali vapours are used in applications such as atomic clocks, optical signal processing, generation of squeezed light and Raman quantum memories for temporal multiplexing. To achieve a strong interaction the alkali ensemble needs both a large optical depth and a high level of spin-polarisation. We implement a technique known as quenching using a molecular buffer gas which allows near-perfect spin-polarisation of over 99.5 % in caesium vapour at high optical depths of up to ∼ 2× {10}5; a factor of 4 higher than can be achieved without quenching. We use this system to explore efficient light storage with high gain in a GHz bandwidth Raman memory.

  16. High efficiency GaP power conversion for Betavoltaic applications (United States)

    Sims, Paul E.; Dinetta, Louis C.; Barnett, Allen M.


    AstroPower is developing a gallium phosphide (GaP) based energy converter optimized for radio luminescent light-based power supplies. A 'two-step' or 'indirect' process is used where a phosphor is excited by radioactive decay products to produce light that is then converted to electricity by a photovoltaic energy converter. This indirect conversion of beta-radiation to electrical energy can be realized by applying recent developments in tritium based radio luminescent (RL) light sources in combination with the high conversion efficiencies that can be achieved under low illumination with low leakage, gallium phosphide based devices. This tritium to light approach is inherently safer than battery designs that incorporate high activity radionuclides because the beta particles emitted by tritium are of low average energy and are easily stopped by a thin layer of glass. GaP layers were grown by liquid phase epitaxy and p/n junction devices were fabricated and characterized for low light intensity power conversion. AstroPower has demonstrated the feasibility of the GaP based energy converter with the following key results: 23.54 percent conversion efficiency under 968 muW/sq cm 440 nm blue light, 14.59 percent conversion efficiency for 2.85 muW/sq cm 440 nm blue light, and fabrication of working 5 V array. We have also determined that at least 20 muW/sq cm optical power is available for betavoltaic power systems. Successful developments of this device is an enabling technology for low volume, safe, high voltage, milliwatt power supplies with service lifetimes in excess of 12 years.

  17. Optimization of peptide nucleic acid fluorescence in situ hybridization (PNA-FISH) for the detection of bacteria: The effect of pH, dextran sulfate and probe concentration. (United States)

    Rocha, Rui; Santos, Rita S; Madureira, Pedro; Almeida, Carina; Azevedo, Nuno F


    Fluorescence in situ hybridization (FISH) is a molecular technique widely used for the detection and characterization of microbial populations. FISH is affected by a wide variety of abiotic and biotic variables and the way they interact with each other. This is translated into a wide variability of FISH procedures found in the literature. The aim of this work is to systematically study the effects of pH, dextran sulfate and probe concentration in the FISH protocol, using a general peptide nucleic acid (PNA) probe for the Eubacteria domain. For this, response surface methodology was used to optimize these 3 PNA-FISH parameters for Gram-negative (Escherichia coli and Pseudomonas fluorescens) and Gram-positive species (Listeria innocua, Staphylococcus epidermidis and Bacillus cereus). The obtained results show that a probe concentration higher than 300nM is favorable for both groups. Interestingly, a clear distinction between the two groups regarding the optimal pH and dextran sulfate concentration was found: a high pH (approx. 10), combined with lower dextran sulfate concentration (approx. 2% [w/v]) for Gram-negative species and near-neutral pH (approx. 8), together with higher dextran sulfate concentrations (approx. 10% [w/v]) for Gram-positive species. This behavior seems to result from an interplay between pH and dextran sulfate and their ability to influence probe concentration and diffusion towards the rRNA target. This study shows that, for an optimum hybridization protocol, dextran sulfate and pH should be adjusted according to the target bacteria. Copyright © 2016 Elsevier B.V. All rights reserved.

  18. A High Efficiency PSOFC/ATS-Gas Turbine Power System

    Energy Technology Data Exchange (ETDEWEB)

    W.L. Lundberg; G.A. Israelson; M.D. Moeckel; S.E. Veyo; R.A. Holmes; P.R. Zafred; J.E. King; R.E. Kothmann


    A study is described in which the conceptual design of a hybrid power system integrating a pressurized Siemens Westinghouse solid oxide fuel cell generator and the Mercury{trademark} 50 gas turbine was developed. The Mercury{trademark} 50 was designed by Solar Turbines as part of the US. Department of Energy Advanced Turbine Systems program. The focus of the study was to develop the hybrid power system concept that principally would exhibit an attractively-low cost of electricity (COE). The inherently-high efficiency of the hybrid cycle contributes directly to achieving this objective, and by employing the efficient, power-intensive Mercury{trademark} 50, with its relatively-low installed cost, the higher-cost SOFC generator can be optimally sized such that the minimum-COE objective is achieved. The system cycle is described, major system components are specified, the system installed cost and COE are estimated, and the physical arrangement of the major system components is discussed. Estimates of system power output, efficiency, and emissions at the system design point are also presented. In addition, two bottoming cycle options are described, and estimates of their effects on overall-system performance, cost, and COE are provided.

  19. Predicting high harmonic ion cyclotron heating efficiency in Tokamak plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Green, David L [ORNL; Jaeger, E. F. [XCEL; Berry, Lee A [ORNL; Chen, Guangye [ORNL; Ryan, Philip Michael [ORNL; Canik, John [ORNL


    Observations of improved radio frequency (RF) heating efficiency in high-confinement (H-) mode plasmas on the National Spherical Tokamak Experiment (NSTX) are investigated by whole-device linear simulation. We present the first full-wave simulation to couple kinetic physics of the well confined core plasma to the poorly confined scrape-off plasma. The new simulation is used to scan the launched fast-wave spectrum and examine the steady-state electric wave field structure for experimental scenarios corresponding to both reduced, and improved RF heating efficiency. We find that launching toroidal wave-numbers that required for fast-wave propagation excites large amplitude (kVm 1 ) coaxial standing modes in the wave electric field between the confined plasma density pedestal and conducting vessel wall. Qualitative comparison with measurements of the stored plasma energy suggest these modes are a probable cause of degraded heating efficiency. Also, the H-mode density pedestal and fast-wave cutoff within the confined plasma allow for the excitation of whispering gallery type eigenmodes localised to the plasma edge.

  20. Highly efficient entanglement swapping and teleportation at telecom wavelength. (United States)

    Jin, Rui-Bo; Takeoka, Masahiro; Takagi, Utako; Shimizu, Ryosuke; Sasaki, Masahide


    Entanglement swapping at telecom wavelengths is at the heart of quantum networking in optical fiber infrastructures. Although entanglement swapping has been demonstrated experimentally so far using various types of entangled photon sources both in near-infrared and telecom wavelength regions, the rate of swapping operation has been too low to be applied to practical quantum protocols, due to limited efficiency of entangled photon sources and photon detectors. Here we demonstrate drastic improvement of the efficiency at telecom wavelength by using two ultra-bright entangled photon sources and four highly efficient superconducting nanowire single photon detectors. We have attained a four-fold coincidence count rate of 108 counts per second, which is three orders higher than the previous experiments at telecom wavelengths. A raw (net) visibility in a Hong-Ou-Mandel interference between the two independent entangled sources was 73.3 ± 1.0% (85.1 ± 0.8%). We performed the teleportation and entanglement swapping, and obtained a fidelity of 76.3% in the swapping test. Our results on the coincidence count rates are comparable with the ones ever recorded in teleportation/swapping and multi-photon entanglement generation experiments at around 800 nm wavelengths. Our setup opens the way to practical implementation of device-independent quantum key distribution and its distance extension by the entanglement swapping as well as multi-photon entangled state generation in telecom band infrastructures with both space and fiber links.

  1. Analysis of highly-efficient electric residential HPWHs

    Energy Technology Data Exchange (ETDEWEB)

    Baxter, Van D [ORNL; Murphy, Richard W [ORNL; Rice, C Keith [ORNL; Shen, Bo [ORNL; Gao, Zhiming [ORNL


    A scoping level analysis was conducted to identify electric HPWH concepts that have the potential to achieve or exceed 30% source energy savings compared to a gas tankless water heater (GTWH) representative of the type represented in version beta of the BEopt software developed by the National Renewable Energy Laboratory. The analysis was limited to evaluation of options to improve the energy efficiency of electric HPWH product designs currently on the market in the US. The report first defines the baseline GTWH system and determines its efficiency (source-energy-based adjusted or derated EF of ~0.71). High efficiency components (compressors, pumps, fans, heat exchangers, etc.) were identified and applied to current US HPWH products and analyzed to determine the viability of reaching the target EF. The target site-based energy factor (EF) required for an electric HPWH necessary to provide 30% source energy savings compared to the GTWH baseline unit is then determined to be ~3.19.

  2. Highly Efficient and Reproducible Nonfullerene Solar Cells from Hydrocarbon Solvents

    KAUST Repository

    Wadsworth, Andrew


    With chlorinated solvents unlikely to be permitted for use in solution-processed organic solar cells in industry, there must be a focus on developing nonchlorinated solvent systems. Here we report high-efficiency devices utilizing a low-bandgap donor polymer (PffBT4T-2DT) and a nonfullerene acceptor (EH-IDTBR) from hydrocarbon solvents and without using additives. When mesitylene was used as the solvent, rather than chlorobenzene, an improved power conversion efficiency (11.1%) was achieved without the need for pre- or post-treatments. Despite altering the processing conditions to environmentally friendly solvents and room-temperature coating, grazing incident X-ray measurements confirmed that active layers processed from hydrocarbon solvents retained the robust nanomorphology obtained with hot-processed chlorinated solvents. The main advantages of hydrocarbon solvent-processed devices, besides the improved efficiencies, were the reproducibility and storage lifetime of devices. Mesitylene devices showed better reproducibility and shelf life up to 4000 h with PCE dropping by only 8% of its initial value.

  3. High performance metamaterial device with enhanced electromagnetic energy harvesting efficiency (United States)

    Shang, Shuai; Yang, Shizhong; Shan, Meng; Liu, Jing; Cao, Hailin


    A high performance metamaterial device for electromagnetic energy harvesting is presented. The unit cell of the metamaterial device consists of four identical omega ring resonators arranged in rotational symmetry, and each omega ring is loaded with a 50 Ω resistor that mimics the input impedance of a rectifier circuit. A proof-of-concept prototype is designed for operation at the frequency of 5.8 GHz. Here, the efficient energy harvesting is validated by the energy dissipated in each resistor. Based on the full absorption concept, the metamaterial device achieves a harvesting efficiency up to 93.1% under normal incidence. In addition, the energy harvester shows polarization independent and wide-angle incident frequency responses with good harvesting characteristics over the entire operating range. The surface current distribution is analyzed to gain an insight into the energy harvesting mechanism. Moreover, the harvester prototype is manufactured and measured, and the simulated and measured results are in good agreement. Due to the enhanced electromagnetic energy harvesting efficiency, the proposed device is a good candidate for microwave power transmission.

  4. High-efficiency shock-wave generator for extracorporeal lithotripsy. (United States)

    Broyer, P; Cathignol, D; Theillère, Y; Mestas, J L


    In extracorporeal lithotripsy, the electro-acoustic efficiency of electrohydraulic generators is limited by the inductance of the electrical discharge circuit. A new shock-wave generator is described that uses a coaxial discharge line enabling electro-acoustic efficiency to be greatly increased. The line is built using a para-electric ceramic with a relative dielectric constant of 1700, manufactured for use in high-voltage impulse mode. A coaxial spark gap, with minimal inductance, has been developed to obtain the triggered breakdown of the discharge line. Shock waves are created with a coaxial electrode plugged directly into the spark gap and immersed in an electrolyte of degassed saline. Electrode gap and electrolyte resistivity are adjusted to match the resistivity of the electrolyte volume between the underwater electrodes to the characteristic impedance of the line. The discharge line generates in the medium a rectangular current pulse with an amplitude of about 6000 A and a rise time of 50 ns. Compared with conventional generators, measurements of the expansive peak pressure pulse show an increase of 105% at 10 kV, 86.5% at 12 kV and 34.5% at 14 kV charging voltage. Electro-acoustic efficiency is found to be 11% instead of 5.5% for a conventional discharge circuit.

  5. High quantum efficiency S-20 photocathodes in photon counting detectors (United States)

    Orlov, D. A.; DeFazio, J.; Duarte Pinto, S.; Glazenborg, R.; Kernen, E.


    Based on conventional S-20 processes, a new series of high quantum efficiency (QE) photocathodes has been developed that can be specifically tuned for use in the ultraviolet, blue or green regions of the spectrum. The QE values exceed 30% at maximum response, and the dark count rate is found to be as low as 30 Hz/cm2 at room temperature. This combination of properties along with a fast temporal response makes these photocathodes ideal for application in photon counting detectors, which is demonstrated with an MCP photomultiplier tube for single and multi-photoelectron detection.

  6. Dual Band High Efficiency Power Amplifier Based on CRLH Lines

    Directory of Open Access Journals (Sweden)

    D. Segovia-Vargas


    Full Text Available In this paper we propose the use of Composite Right/Left Hand (CRLH and Extended Composite Right/Left Hand (ECRLH transmission lines for the design of dual band high efficiency power amplifiers working in CE class. The harmonic termination can be synthesized using the meta-lines is particularly suitable for CE class amplifiers, which have a termination not as sensitive to the third harmonic as F class amplifier. This paper presents the design procedure and the design equations. The nonlinear phase response of a CRLH and ECRLH transmission line has been utilized to design arbitrary dual-band amplifiers.

  7. Biotechnological approach towards a highly efficient production of natural prostaglandins. (United States)

    Guder, J C; Buchhaupt, M; Huth, I; Hannappel, A; Ferreirós, N; Geisslinger, G; Schrader, J


    Prostaglandins (PGs) act as potent local hormones in nearly all tissues of the human body and are used for various medical applications. Heterologous expression of PG endoperoxide H-synthase from the alga, Gracilaria vermiculophylla, into E. coli and the application of this strain in biotransformation experiments resulted in a highly efficient conversion of arachidonic acid (ARA) yielding up to 130 mg natural PGs l(-1) in a laboratory scale approach. Detailed analyses of the products and production kinetics were performed, confirming a rapid conversion of ARA to PGs.

  8. Polarization holograms allow highly efficient generation of complex light beams. (United States)

    Ruiz, U; Pagliusi, P; Provenzano, C; Volke-Sepúlveda, K; Cipparrone, Gabriella


    We report a viable method to generate complex beams, such as the non-diffracting Bessel and Weber beams, which relies on the encoding of amplitude information, in addition to phase and polarization, using polarization holography. The holograms are recorded in polarization sensitive films by the interference of a reference plane wave with a tailored complex beam, having orthogonal circular polarizations. The high efficiency, the intrinsic achromaticity and the simplicity of use of the polarization holograms make them competitive with respect to existing methods and attractive for several applications. Theoretical analysis, based on the Jones formalism, and experimental results are shown.

  9. High efficiency power production from biomass and waste

    Energy Technology Data Exchange (ETDEWEB)

    Rabou, L.P.L.M.; Van Leijenhorst, R.J.C.; Hazewinkel, J.H.O. [ECN Biomass, Coal and Environment, Petten (Netherlands)


    Two-stage gasification allows power production from biomass and waste with high efficiency. The process involves pyrolysis at about 550C followed by heating of the pyrolysis gas to about 1300C in order to crack hydrocarbons and obtain syngas, a mixture of H2, CO, H2O and CO2. The second stage produces soot as unwanted by-product. Experimental results are reported on the suppression of soot formation in the second stage for two different fuels: beech wood pellets and Rofire pellets, made from rejects of paper recycling. Syngas obtained from these two fuels and from an industrial waste fuel has been cleaned and fed to a commercial SOFC stack for 250 hours in total. The SOFC stack showed comparable performance on real and synthetic syngas and no signs of accelerated degradation in performance over these tests. The experimental results have been used for the design and analysis of a future 25 MWth demonstration plant. As an alternative, a 2.6 MWth system was considered which uses the Green MoDem approach to convert waste fuel into bio-oil and syngas. The 25 MWth system can reach high efficiency only if char produced in the pyrolysis step is converted into additional syngas by steam gasification, and if SOFC off-gas and system waste heat are used in a steam bottoming cycle for additional power production. A net electrical efficiency of 38% is predicted. In addition, heat can be delivered with 37% efficiency. The 2.6 MWth system with only a dual fuel engine to burn bio-oil and syngas promises nearly 40% electrical efficiency plus 41% efficiency for heat production. If syngas is fed to an SOFC system and off-gas and bio-oil to a dual fuel engine, the electrical efficiency can rise to 45%. However, the efficiency for heat production drops to 15%, as waste heat from the SOFC system cannot be used effectively. The economic analysis makes clear that at -20 euro/tonne fuel, 70 euro/MWh for electricity and 7 euro/GJ for heat the 25 MWth system is not economically viable at the

  10. Hybrid DNA i-motif: Aminoethylprolyl-PNA (pC5) enhance the stability of DNA (dC5) i-motif structure. (United States)

    Gade, Chandrasekhar Reddy; Sharma, Nagendra K


    This report describes the synthesis of C-rich sequence, cytosine pentamer, of aep-PNA and its biophysical studies for the formation of hybrid DNA:aep-PNAi-motif structure with DNA cytosine pentamer (dC 5 ) under acidic pH conditions. Herein, the CD/UV/NMR/ESI-Mass studies strongly support the formation of stable hybrid DNA i-motif structure with aep-PNA even near acidic conditions. Hence aep-PNA C-rich sequence cytosine could be considered as potential DNA i-motif stabilizing agents in vivo conditions. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. High efficiency, multiterawatt x-ray free electron lasers

    Directory of Open Access Journals (Sweden)

    C. Emma


    Full Text Available In this paper we present undulator magnet tapering methods for obtaining high efficiency and multiterawatt peak powers in x-ray free electron lasers (XFELs, a key requirement for enabling 3D atomic resolution single molecule imaging and nonlinear x-ray science. The peak power and efficiency of tapered XFELs is sensitive to time dependent effects, like synchrotron sideband growth. To analyze this dependence in detail we perform a comparative numerical optimization for the undulator magnetic field tapering profile including and intentionally disabling these effects. We show that the solution for the magnetic field taper profile obtained from time independent optimization does not yield the highest extraction efficiency when time dependent effects are included. Our comparative optimization is performed for a novel undulator designed specifically to obtain TW power x-ray pulses in the shortest distance: superconducting, helical, with short period and built-in strong focusing. This design reduces the length of the breaks between modules, decreasing diffraction effects, and allows using a stronger transverse electron focusing. Both effects reduce the gain length and the overall undulator length. We determine that after a fully time dependent optimization of a 100 m long Linac coherent light source-like XFEL we can obtain a maximum efficiency of 7%, corresponding to 3.7 TW peak radiation power. Possible methods to suppress the synchrotron sidebands, and further enhance the FEL peak power, up to about 6 TW by increasing the seed power and reducing the electron beam energy spread, are also discussed.

  12. Hexagonal boron nitride neutron detectors with high detection efficiencies (United States)

    Maity, A.; Grenadier, S. J.; Li, J.; Lin, J. Y.; Jiang, H. X.


    Neutron detectors fabricated from 10B enriched hexagonal boron nitride (h-10BN or h-BN) epilayers have demonstrated the highest thermal neutron detection efficiency among solid-state neutron detectors to date at about 53%. In this work, photoconductive-like vertical detectors with a detection area of 1 × 1 mm2 were fabricated from 50 μm thick free-standing h-BN epilayers using Ni/Au and Ti/Al bilayers as ohmic contacts. Leakage currents, mobility-lifetime (μτ) products under UV photoexcitation, and neutron detection efficiencies have been measured for a total of 16 different device configurations. The results have unambiguously identified that detectors incorporating the Ni/Au bilayer on both surfaces as ohmic contacts and using the negatively biased top surface for neutron irradiation are the most desired device configurations. It was noted that high growth temperatures of h-10BN epilayers on sapphire substrates tend to yield a higher concentration of oxygen impurities near the bottom surface, leading to a better device performance by the chosen top surface for irradiation than by the bottom. Preferential scattering of oxygen donors tends to reduce the mobility of holes more than that of electrons, making the biasing scheme with the ability of rapidly extracting holes at the irradiated surface while leaving the electrons to travel a large average distance inside the detector at a preferred choice. When measured against a calibrated 6LiF filled micro-structured semiconductor neutron detector, it was shown that the optimized configuration has pushed the detection efficiency of h-BN neutron detectors to 58%. These detailed studies also provided a better understanding of growth-mediated impurities in h-BN epilayers and their effects on the charge collection and neutron detection efficiencies.

  13. Next generation of high-efficient waste incinerators. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Jappe Frandsen, F.


    Modern society produces increasing amounts of combustible waste which may be utilized for heat and power production, at a lower emission of CO{sub 2}, e.g. by substituting a certain fraction of energy from fossil fuel-fired power stations. In 2007, 20.4 % of the district heating and 4.5 % of the power produced in Denmark came from thermal conversion of waste, and waste is a very important part of a future sustainable, and independent, Danish energy supply [Frandsen et al., 2009; Groen Energi, 2010]. In Denmark, approx 3.3 Mtons of waste was produced in 2005, an amount predicted to increase to 4.4 Mtons by the year 2030. According to Affald Danmark, 25 % of the current WtE plant capacity in Denmark is older than 20 years, which is usually considered as the technical and economical lifetime of WtE plants. Thus, there is a need for installation of a significant fraction of new waste incineration capacity, preferentially with an increased electrical efficiency, within the next few years. Compared to fossil fuels, waste is difficult to handle in terms of pre-treatment, combustion, and generation of reusable solid residues. In particular, the content of inorganic species (S, Cl, K, Na, etc.) is problematic, due to enhanced deposition and corrosion - especially at higher temperatures. This puts severe constraints on the electrical efficiency of grate-fired units utilizing waste, which seldom exceeds 26-27%, campared to 46-48 % for coal combustion in suspension. The key parameters when targeting higher electrical efficiency are the pressure and temperature in the steam cycle, which are limited by high-temperature corrosion, boiler- and combustion-technology. This report reviews some of the means that can be applied in order to increase the electrical efficiency in plants firing waste on a grate. (Author)

  14. High-efficiency photonic crystal narrowband thermal emitters (United States)

    Farfan, G. B.; Su, M. F.; Reda Taha, M. M.; El-Kady, I.


    Photonic crystals (PhC) are artificial structures fabricated with a periodicity in the dielectric function. This periodic electromagnetic potential results in creation of energy bandgaps where photon propagation is prohibited. PhC structures have promising use in thermal applications if optimized to operate at specific thermal emission spectrum. Here, novel utilization of optimized PhC's in thermal applications is presented. We demonstrate through numerical simulation the modification of the thermal emission spectrum by a metallic photonic crystal (PhC) to create high-efficiency multispectral thermal emitters. These emitters funnel radiation from a broad emission spectrum associated with a Plancklike distribution into a prescribed narrow emission band. A detailed quantitative evaluation of the spectral and power efficiencies of a PhC thermal emitter and its portability across infrared (IR) spectral bands are provided. We show an optimized tungsten PhC with a predominant narrow-band emission profile with an emitter efficiency that is more than double that of an ideal blackbody and ~65-75% more power-efficiency across the IR spectrum. We also report on using optimal three-dimensional Lincoln log photonic crystal (LL-PhC) emitters for thermophotovoltaic (TPV) generation as opposed to using a passive filtering approach to truncate the broadband thermal source emission to match the bandgap of a photovoltaic (PV) cell. The emitter performance is optimized for the 1-2μm PV band using different PhC materials, specifically copper, silver and gold. The use of the proposed PhC in TPV devices can produce significant energy savings not reported before. The optimal design of the PhC geometry is obtained by implementing a variety of optimization methods integrated with artificial intelligence (AI) algorithms.

  15. High-Efficiency Nitride-Base Photonic Crystal Light Sources

    Energy Technology Data Exchange (ETDEWEB)

    James Speck; Evelyn Hu; Claude Weisbuch; Yong-Seok Choi; Kelly McGroddy; Gregor Koblmuller; Elison Matioli; Elizabeth Rangel; Fabian Rol; Dobri Simeonov


    The research activities performed in the framework of this project represent a major breakthrough in the demonstration of Photonic Crystals (PhC) as a competitive technology for LEDs with high light extraction efficiency. The goals of the project were to explore the viable approaches to manufacturability of PhC LEDS through proven standard industrial processes, establish the limits of light extraction by various concepts of PhC LEDs, and determine the possible advantages of PhC LEDs over current and forthcoming LED extraction concepts. We have developed three very different geometries for PhC light extraction in LEDs. In addition, we have demonstrated reliable methods for their in-depth analysis allowing the extraction of important parameters such as light extraction efficiency, modal extraction length, directionality, internal and external quantum efficiency. The information gained allows better understanding of the physical processes and the effect of the design parameters on the light directionality and extraction efficiency. As a result, we produced LEDs with controllable emission directionality and a state of the art extraction efficiency that goes up to 94%. Those devices are based on embedded air-gap PhC - a novel technology concept developed in the framework of this project. They rely on a simple and planar fabrication process that is very interesting for industrial implementation due to its robustness and scalability. In fact, besides the additional patterning and regrowth steps, the process is identical as that for standard industrially used p-side-up LEDs. The final devices exhibit the same good electrical characteristics and high process yield as a series of test standard LEDs obtained in comparable conditions. Finally, the technology of embedded air-gap patterns (PhC) has significant potential in other related fields such as: increasing the optical mode interaction with the active region in semiconductor lasers; increasing the coupling of the incident


    Energy Technology Data Exchange (ETDEWEB)



    OAK B202 HIGH EFFICIENCY GENERATION OF HYDROGEN FUELS USING NUCLEAR POWER. Combustion of fossil fuels, used to power transportation, generate electricity, heat homes and fuel industry provides 86% of the world's energy. Drawbacks to fossil fuel utilization include limited supply, pollution, and carbon dioxide emissions. Carbon dioxide emissions, thought to be responsible for global warming, are now the subject of international treaties. Together, these drawbacks argue for the replacement of fossil fuels with a less-polluting potentially renewable primary energy such as nuclear energy. Conventional nuclear plants readily generate electric power but fossil fuels are firmly entrenched in the transportation sector. Hydrogen is an environmentally attractive transportation fuel that has the potential to displace fossil fuels. Hydrogen will be particularly advantageous when coupled with fuel cells. Fuel cells have higher efficiency than conventional battery/internal combustion engine combinations and do not produce nitrogen oxides during low-temperature operation. Contemporary hydrogen production is primarily based on fossil fuels and most specifically on natural gas. When hydrogen is produced using energy derived from fossil fuels, there is little or no environmental advantage. There is currently no large scale, cost-effective, environmentally attractive hydrogen production process available for commercialization, nor has such a process been identified. The objective of this work is to find an economically feasible process for the production of hydrogen, by nuclear means, using an advanced high-temperature nuclear reactor as the primary energy source. Hydrogen production by thermochemical water-splitting (Appendix A), a chemical process that accomplishes the decomposition of water into hydrogen and oxygen using only heat or, in the case of a hybrid thermochemical process, by a combination of heat and electrolysis, could meet these goals. Hydrogen produced from

  17. High-efficiency, high-power and low threshold Yb3+:YAG ceramic laser. (United States)

    Pirri, Angela; Alderighi, Daniele; Toci, Guido; Vannini, Matteo


    We present a high-power, high-efficiency and low threshold laser prototype based on doped ceramic Yb(3+):YAG. We achieved an output power of 9 W with a slope efficiency of 73% and a threshold of 1 W at 1030 nm in quasi-Continuous Wave (QCW). Moreover, we obtained an output power 7.7 W with a slope efficiency of 60% in Continuous Wave (CW). Finally, a characterization of a low losses tunable cavity for several laser wavelengths with an output power exceeding 5 W is reported.

  18. The analysis of energy efficiency in water electrolysis under high temperature and high pressure (United States)

    Hourng, L. W.; Tsai, T. T.; Lin, M. Y.


    This paper aims to analyze the energy efficiency of water electrolysis under high pressure and high temperature conditions. The effects of temperature and pressure on four different kinds of reaction mechanisms, namely, reversible voltage, activation polarization, ohmic polarization, and concentration polarization, are investigated in details. Results show that the ohmic and concentration over-potentials are increased as temperature is increased, however, the reversible and activation over-potentials are decreased as temperature is increased. Therefore, the net efficiency is enhanced as temperature is increased. The efficiency of water electrolysis at 350°C/100 bars is increased about 17%, compared with that at 80°C/1bar.

  19. High Current Planar Transformer for Very High Efficiency Isolated Boost DC-DC Converters

    DEFF Research Database (Denmark)

    Pittini, Riccardo; Zhang, Zhe; Andersen, Michael A. E.


    This paper presents a design and optimization of a high current planar transformer for very high efficiency dc-dc isolated boost converters. The analysis considers different winding arrangements, including very high copper thickness windings. The analysis is focused on the winding ac......-resistance and transformer leakage inductance. Design and optimization procedures are validated based on an experimental prototype of a 6 kW dcdc isolated full bridge boost converter developed on fully planar magnetics. The prototype is rated at 30-80 V 0-80 A on the low voltage side and 700-800 V on the high voltage side...... with a peak efficiency of 97.8% at 80 V 3.5 kW. Results highlights that thick copper windings can provide good performance at low switching frequencies due to the high transformer filling factor. PCB windings can also provide very high efficiency if stacked in parallel utilizing the transformer winding window...

  20. Novel Concepts for High-Efficiency Lightweight Space Solar Cells

    Directory of Open Access Journals (Sweden)

    Cappelluti F.


    Full Text Available One of the key issues in the design and development of a satellite Photovoltaic Assembly (PVA is the trade-off to be made between the available volume located to the PVA, its mass and the total amount of power that the solar panels have to guarantee to the spacecraft. The development of high-efficiency, flexible, lightweight solar cells is therefore instrumental to the design of future satellites providing enhanced missions and services. Based on the consolidated development of GaAs-based single junction and lattice matched triple-junction solar cells, several research efforts are being pursued worldwide to further increase the efficiency and reduce mass. Promising approaches include thin-film technologies such as Inverted Metamorphic and Epitaxial Lift-Off (ELO, and the use of nanostructures or highly mismatched alloys grown by MBE. We propose here an alternative path towards the development of lightweight GaAs-based solar cells with the potential to exceed the Shockley-Queisser (SQ limit of single junction cells. Our approach is based on the synergistic combination of thin-film design, quantum dots (QDs absorption, and photonic nanostructures. Challenges and opportunities offered by the use of QDs are discussed. A cost-effective and scalable fabrication process including ELO technology and nanoimprint lithography is outlined. Finally, a proof-of-concept design, based on rigorous electromagnetic and physics-based simulations, is presented. Efficiency higher than 30% and weight reduction close to 90% - owing to the substrate removal - makes the proposed device to rank record power-to-weight ratio, with the potential to become a cost-effective, attractive option for next generation space solar cells.

  1. High-efficient Unmanned Aircraft System Operations for Ecosystem Assessment (United States)

    Xu, H.; Zhang, H.


    Diverse national and international agencies support the idea that incorporating Unmanned Aircraft Systems (UAS) into ecosystem assessment will improve the operations efficiency and accuracy. In this paper, a UAS will be designed to monitor the Gulf of Mexico's coastal area ecosystems intelligently and routinely. UAS onboard sensors will capture information that can be utilized to detect and geo-locate areas affected by invasive grasses. Moreover, practical ecosystem will be better assessed by analyzing the collected information. Compared with human-based/satellite-based surveillance, the proposed strategy is more efficient and accurate, and eliminates limitations and risks associated with human factors. State of the art UAS onboard sensors (e.g. high-resolution electro optical camera, night vision camera, thermal sensor etc.) will be used for monitoring coastal ecosystems. Once detected the potential risk in ecosystem, the onboard GPS data will be used to geo-locate and to store the exact coordinates of the affected area. Moreover, the UAS sensors will be used to observe and to record the daily evolution of coastal ecosystems. Further, benefitting from the data collected by the UAS, an intelligent big data processing scheme will be created to assess the ecosystem evolution effectively. Meanwhile, a cost-efficient intelligent autonomous navigation strategy will be implemented into the UAS, in order to guarantee that the UAS can fly over designated areas, and collect significant data in a safe and effective way. Furthermore, the proposed UAS-based ecosystem surveillance and assessment methodologies can be utilized for natural resources conservation. Flying UAS with multiple state of the art sensors will monitor and report the actual state of high importance natural resources frequently. Using the collected data, the ecosystem conservation strategy can be performed effectively and intelligently.

  2. In-Plant Testing of High-Efficiency Hydraulic Separators

    Energy Technology Data Exchange (ETDEWEB)

    G. H. Luttrell; R. Q. Honaker; R. C. Bratton; T. C. Westerfield; J. N. Kohmuench


    The mineral processing industry has commonly utilized hydraulic separators throughout history for classification and gravity concentration of various minerals. More commonly referred to as hindered-bed or fluidized-bed separators, these units make use of differential particle settling rates to segregate particles according to shape, size, and/or density. As with any equipment, there are inefficiencies associated with its operation, which prompted an industry driven research program to further evaluate two novel high-efficiency hindered bed separators. These units, which are commercially called the CrossFlow separator and HydroFloat separator, have the potential to improve performance (separation efficiency and throughput) and reduce operating costs (power consumption, water and reagent usage). This report describes the results of Phase I activities (laboratory and pilot-scale tests) conducted with the CrossFlow and HydroFloat separators at several locations in the minerals and coal industries. Details of the testing programs (equipment setup, shakedown testing and detailed testing) associated with four coal plants and two phosphate plants are summarized in this work. In most of these applications, the high-efficiency units proved to provide a higher quality product at reduced costs when compared against the performance of conventional separators. Based on promising results obtained from Phase I, full-scale prototypes will be purchased by several mining companies for use in Phase II of this project. Two of the prototype units, which will be constructed by Eriez Manufacturing, are expected to be installed by a major U.S. phosphate producer and a large eastern U.S. coal company. Negotiations are also underway to purchase and install additional prototype units by a mineral sands producer and a second phosphate producer. The data obtained from the full-scale evaluations will be used to further promote commercialization and industrial applications of these innovative

  3. Nanocoatings for High-Efficiency Industrial Hydraulic and Tooling Systems

    Energy Technology Data Exchange (ETDEWEB)

    Clifton B. Higdon III


    Industrial manufacturing in the U.S. accounts for roughly one third of the 98 quadrillion Btu total energy consumption. Motor system losses amount to 1.3 quadrillion Btu, which represents the largest proportional loss of any end-use category, while pumps alone represent over 574 trillion BTU (TBTU) of energy loss each year. The efficiency of machines with moving components is a function of the amount of energy lost to heat because of friction between contacting surfaces. The friction between these interfaces also contributes to downtime and the loss of productivity through component wear and subsequent repair. The production of new replacement parts requires additional energy. Among efforts to reduce energy losses, wear-resistant, low-friction coatings on rotating and sliding components offer a promising approach that is fully compatible with existing equipment and processes. In addition to lubrication, one of the most desirable solutions is to apply a protective coating or surface treatment to rotating or sliding components to reduce their friction coefficients, thereby leading to reduced wear. Historically, a number of materials such as diamond-like carbon (DLC), titanium nitride (TiN), titanium aluminum nitride (TiAlN), and tungsten carbide (WC) have been examined as tribological coatings. The primary objective of this project was the development of a variety of thin film nanocoatings, derived from the AlMgB14 system, with a focus on reducing wear and friction in both industrial hydraulics and cutting tool applications. Proof-of-concept studies leading up to this project had shown that the constituent phases, AlMgB14 and TiB2, were capable of producing low-friction coatings by pulsed laser deposition. These coatings combine high hardness with a low friction coefficient, and were shown to substantially reduce wear in laboratory tribology tests. Selection of the two applications was based largely on the concept of improved mechanical interface efficiencies for

  4. High efficiency video coding coding tools and specification

    CERN Document Server

    Wien, Mathias


    The video coding standard High Efficiency Video Coding (HEVC) targets at improved compression performance for video resolutions of HD and beyond, providing Ultra HD video at similar compressed bit rates as for HD video encoded with the well-established video coding standard H.264 | AVC. Based on known concepts, new coding structures and improved coding tools have been developed and specified in HEVC. The standard is expected to be taken up easily by established industry as well as new endeavors, answering the needs of todays connected and ever-evolving online world. This book presents the High Efficiency Video Coding standard and explains it in a clear and coherent language. It provides a comprehensive and consistently written description, all of a piece. The book targets at both, newbies to video coding as well as experts in the field. While providing sections with introductory text for the beginner, it suits as a well-arranged reference book for the expert. The book provides a comprehensive reference for th...

  5. Demonstration of highly efficient lithium–sulfur batteries

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Rui; Li, James C. M.; Lu, Jun; Amine, Khalil; Belharouak, Ilias


    Lithium–sulfur coin cells were tested with the aim of mitigating the issue of polysulfide dissolution. Five approaches were investigated: optimization of the amount of sulfur that can be contained in the sulfur/carbon electrodes, introduction of different forms of carbon additives into the sulfur electrodes, impregnation of sulfur into the pores of high-surface-area carbon via a melting process, addition of high-surface-area TiO2 as a polysulfide-adsorbing agent in the sulfur electrodes, and use of lithium nitrate as an additive in the electrolyte. Among all these approaches, the most effective way to inhibit the shuttle phenomenon and improve the coulombic efficiency of the Li–S battery was the addition of LiNO3 into the electrolyte.

  6. High Efficiency, Low Emissions Homogeneous Charge Compression Ignition (HCCI) Engines

    Energy Technology Data Exchange (ETDEWEB)

    Gravel, Roland [U.S. Department of Energy' s Vehicle Technologies Office, Washington, DC (United States); Maronde, Carl [National Energy Technology Lab. (NETL), Albany, OR (United States); Gehrke, Chris [Caterpillar, Inc., Peoria, IL (United States); Fiveland, Scott [Caterpillar, Inc., Peoria, IL (United States)


    This is the final report of the High Efficiency Clean Combustion (HECC) Research Program for the U.S. Department of Energy. Work under this co-funded program began in August 2005 and finished in July 2010. The objective of this program was to develop and demonstrate a low emission, high thermal efficiency engine system that met 2010 EPA heavy-duty on-highway truck emissions requirements (0.2g/bhp-hr NOx, 0.14g/bhp-hr HC and 0.01g/bhp-hr PM) with a thermal efficiency of 46%. To achieve this goal, development of diesel homogenous charge compression ignition (HCCI) combustion was the chosen approach. This report summarizes the development of diesel HCCI combustion and associated enabling technologies that occurred during the HECC program between August 2005 and July 2010. This program showed that although diesel HCCI with conventional US diesel fuel was not a feasible means to achieve the program objectives, the HCCI load range could be increased with a higher volatility, lower cetane number fuel, such as gasoline, if the combustion rate could be moderated to avoid excessive cylinder pressure rise rates. Given the potential efficiency and emissions benefits, continued research of combustion with low cetane number fuels and the effects of fuel distillation are recommended. The operation of diesel HCCI was only feasible at part-load due to a limited fuel injection window. A 4% fuel consumption benefit versus conventional, low-temperature combustion was realized over the achievable operating range. Several enabling technologies were developed under this program that also benefited non-HCCI combustion. The development of a 300MPa fuel injector enabled the development of extended lifted flame combustion. A design methodology for minimizing the heat transfer to jacket water, known as precision cooling, will benefit conventional combustion engines, as well as HCCI engines. An advanced combustion control system based on cylinder pressure measurements was developed. A Well

  7. Influence of Regulations on Market Efficiency from the Viewpoint of High-efficiency Cogeneration

    Directory of Open Access Journals (Sweden)

    Maciej Sołtysik


    Full Text Available Formation of a common European energy market implies the necessity of making adjustments to domestic law and adopting market development possibilities in order to meet European Union regulations. Implementation of system support to develop high-efficiency cogeneration was one of those aspects. Several years of such a mechanism functioning allow one to: analyze those regulations and their impact on sub-sector development, make a deep cost analysis and discuss its continuation in the future as well. Taking into account the background of implementation of EU regulations, this paper presents the results of volume-price estimations, current trends, evaluation of property rights regulated in the system, the analysis of market participants’ behaviours, as well as legal issues within this context.

  8. Energy-Efficient Office Buildings at High Latitudes

    Energy Technology Data Exchange (ETDEWEB)

    Lerum, V.


    This doctoral thesis describes a method for energy efficient office building design at high latitudes and cold climates. The method combines daylighting, passive solar heating, solar protection, and ventilative cooling. The thesis focuses on optimal design of an equatorial-facing fenestration system. A spreadsheet framework linking existing simplified methods is used. The daylight analysis uses location specific data on frequency distribution of diffuse daylight on vertical surfaces to estimate energy savings from optimal window and room configurations in combination with a daylight-responsive electric lighting system. The passive solar heating analysis is a generalization of a solar load ratio method adapted to cold climates by combining it with the Norwegian standard NS3031 for winter months when the solar savings fraction is negative. The emphasis is on very high computational efficiency to permit rapid and comprehensive examination of a large number of options early in design. The procedure is illustrated for a location in Trondheim, Norway, testing the relative significance of various design improvement options relative to a base case. The method is also tested for two other locations in Norway, at latitudes 58 and 70 degrees North. The band of latitudes between these limits covers cities in Alaska, Canada, Greenland, Iceland, Scandinavia, Finland, Russia, and Northern Japan. A comprehensive study of the ``whole building approach`` shows the impact of integrated daylighting and low-energy design strategies. In general, consumption of lighting electricity may be reduced by 50-80%, even at extremely high latitudes. The reduced internal heat from electric lights is replaced by passive solar heating. 113 refs., 85 figs., 25 tabs.

  9. High Efficiency and Low Cost Thermal Energy Storage System

    Energy Technology Data Exchange (ETDEWEB)

    Sienicki, James J. [Argonne National Lab. (ANL), Argonne, IL (United States). Nuclear Engineering Division; Lv, Qiuping [Argonne National Lab. (ANL), Argonne, IL (United States). Nuclear Engineering Division; Moisseytsev, Anton [Argonne National Lab. (ANL), Argonne, IL (United States). Nuclear Engineering Division; Bucknor, Matthew [Argonne National Lab. (ANL), Argonne, IL (United States). Nuclear Engineering Division


    BgtL, LLC (BgtL) is focused on developing and commercializing its proprietary compact technology for processes in the energy sector. One such application is a compact high efficiency Thermal Energy Storage (TES) system that utilizes the heat of fusion through phase change between solid and liquid to store and release energy at high temperatures and incorporate state-of-the-art insulation to minimize heat dissipation. BgtL’s TES system would greatly improve the economics of existing nuclear and coal-fired power plants by allowing the power plant to store energy when power prices are low and sell power into the grid when prices are high. Compared to existing battery storage technology, BgtL’s novel thermal energy storage solution can be significantly less costly to acquire and maintain, does not have any waste or environmental emissions, and does not deteriorate over time; it can keep constant efficiency and operates cleanly and safely. BgtL’s engineers are experienced in this field and are able to design and engineer such a system to a specific power plant’s requirements. BgtL also has a strong manufacturing partner to fabricate the system such that it qualifies for an ASME code stamp. BgtL’s vision is to be the leading provider of compact systems for various applications including energy storage. BgtL requests that all technical information about the TES designs be protected as proprietary information. To honor that request, only non-proprietay summaries are included in this report.

  10. Quality and efficiency in high dimensional Nearest neighbor search

    KAUST Repository

    Tao, Yufei


    Nearest neighbor (NN) search in high dimensional space is an important problem in many applications. Ideally, a practical solution (i) should be implementable in a relational database, and (ii) its query cost should grow sub-linearly with the dataset size, regardless of the data and query distributions. Despite the bulk of NN literature, no solution fulfills both requirements, except locality sensitive hashing (LSH). The existing LSH implementations are either rigorous or adhoc. Rigorous-LSH ensures good quality of query results, but requires expensive space and query cost. Although adhoc-LSH is more efficient, it abandons quality control, i.e., the neighbor it outputs can be arbitrarily bad. As a result, currently no method is able to ensure both quality and efficiency simultaneously in practice. Motivated by this, we propose a new access method called the locality sensitive B-tree (LSB-tree) that enables fast highdimensional NN search with excellent quality. The combination of several LSB-trees leads to a structure called the LSB-forest that ensures the same result quality as rigorous-LSH, but reduces its space and query cost dramatically. The LSB-forest also outperforms adhoc-LSH, even though the latter has no quality guarantee. Besides its appealing theoretical properties, the LSB-tree itself also serves as an effective index that consumes linear space, and supports efficient updates. Our extensive experiments confirm that the LSB-tree is faster than (i) the state of the art of exact NN search by two orders of magnitude, and (ii) the best (linear-space) method of approximate retrieval by an order of magnitude, and at the same time, returns neighbors with much better quality. © 2009 ACM.

  11. Highly efficient and high-power diode-pumped femtosecond Yb:LYSO laser (United States)

    Tian, Wenlong; Wang, Zhaohua; Zhu, Jiangfeng; Zheng, Lihe; Xu, Jun; Wei, Zhiyi


    A diode-pumped high-power femtosecond Yb:LYSO laser with high efficiency is demonstrated. With a semiconductor saturable absorber mirror for passive mode-locking and a Gires-Tournois interferometer mirror for intracavity dispersion compensation, stable mode-locking pulses of 297 fs duration at 1042 nm were obtained. The maximum average power of 3.07 W was realized under 5.17 W absorbed pump power, corresponding to as high as 59.4% opt-opt efficiency. The single pulse energy and peak power are about 35.5 nJ and 119.5 kW, respectively.

  12. A New Very-High-Efficiency R4 Converter for High-Power Fuel Cell Applications

    DEFF Research Database (Denmark)

    Nymand, Morten; Andersen, Michael Andreas E.


    A new very high efficiency 10 kW isolated R4 boost converter for low-voltage high-power fuel cell applications is presented. Using a new concept for partially paralleling of isolated boost converters, only the critical high ac-current parts are paralleled. Four 2.5 kW power stages, consisting...... of fullbridge switching stages and power transformers, operate in parallel on primary side and in series on secondary side. Current sharing is guaranteed by series connection of transformer secondary windings and three small cascaded current balancing transformers on primary side. The detailed design of a 10 k......W prototype converter is presented. Input voltage range is 30-60 V and output voltage is 800 V. Test results, including voltage- and current waveforms and efficiency measurements, are presented. A record high converter efficiency of 98.2 % is achieved. The proposed R4 boost converter thus constitutes a low...

  13. Characterization of three high efficiency and blue sensitive silicon photomultipliers (United States)

    Otte, Adam Nepomuk; Garcia, Distefano; Nguyen, Thanh; Purushotham, Dhruv


    We report about the optical and electrical characterization of three high efficiency and blue sensitive Silicon photomultipliers from FBK, Hamamatsu, and SensL. Key features of the tested devices when operated at 90% breakdown probability are peak photon detection efficiencies between 40% and 55%, temperature dependencies of gain and PDE that are less than 1%/°C, dark rates of ∼50 kHz/mm2 at room temperature, afterpulsing of about 2%, and direct optical crosstalk between 6% and 20%. The characteristics of all three devices impressively demonstrate how the Silicon-photomultiplier technology has improved over the past ten years. It is further demonstrated how the voltage and temperature characteristics of a number of quantities can be parameterized on the basis of physical models. The models provide a deeper understanding of the device characteristics over a wide bias and temperature range. They also serve as examples how producers could provide the characteristics of their SiPMs to users. A standardized parameterization of SiPMs would enable users to find the optimal SiPM for their application and the operating point of SiPMs without having to perform measurements thus significantly reducing design and development cycles.

  14. Novel Intermode Prediction Algorithm for High Efficiency Video Coding Encoder

    Directory of Open Access Journals (Sweden)

    Chan-seob Park


    Full Text Available The joint collaborative team on video coding (JCT-VC is developing the next-generation video coding standard which is called high efficiency video coding (HEVC. In the HEVC, there are three units in block structure: coding unit (CU, prediction unit (PU, and transform unit (TU. The CU is the basic unit of region splitting like macroblock (MB. Each CU performs recursive splitting into four blocks with equal size, starting from the tree block. In this paper, we propose a fast CU depth decision algorithm for HEVC technology to reduce its computational complexity. In 2N×2N PU, the proposed method compares the rate-distortion (RD cost and determines the depth using the compared information. Moreover, in order to speed up the encoding time, the efficient merge SKIP detection method is developed additionally based on the contextual mode information of neighboring CUs. Experimental result shows that the proposed algorithm achieves the average time-saving factor of 44.84% in the random access (RA at Main profile configuration with the HEVC test model (HM 10.0 reference software. Compared to HM 10.0 encoder, a small BD-bitrate loss of 0.17% is also observed without significant loss of image quality.

  15. High Efficiency Driving Electronics for General Illumination LED Luminaires

    Energy Technology Data Exchange (ETDEWEB)

    Upadhyay, Anand


    New generation of standalone LED driver platforms developed, which are more efficient These LED Drivers are more efficient (≥90%), smaller in size ( 0.15 in3/watt), lower in cost ( 12 cents/watt in high volumes in millions of units). And these products are very reliable having an operating life of over 50,000 hours. This technology will enable growth of LED light sources in the use. This will also help in energy saving and reducing total life cycle cost of LED units. Two topologies selected for next generation of LED drivers: 1) Value engineered single stage Flyback topology. This is suitable for low powered LED drivers up to 50W power. 2) Two stage boost power factor correction (PFC) plus LLC half bridge platform for higher powers. This topology is suitable for 40W to 300W LED drivers. Three new product platforms were developed to cover a wide range of LED drivers: 1) 120V 40W LED driver, 2) Intellivolt 75W LED driver, & 3) Intellivolt 150W LED driver. These are standalone LED drivers for rugged outdoor lighting applications. Based on these platforms number of products are developed and successfully introduced in the market place meeting key performance, size and cost goals.

  16. Optimizing Nanopore Surface Properties for High-Efficiency Water Desalination (United States)

    Cohen-Tanugi, David; Grossman, Jeffrey


    As water resources worldwide become rapidly scarcer, it is becoming increasingly important to devise new techniques to obtain clean water from seawater. At present, water purification technologies are limited by costly energy requirements relative to the theoretical thermodynamic limit and by insufficient understanding of the physical processes underlying ion filtration and fluid transport at the molecular scale. New advances in computational materials science offer a promising way to deepen our understanding of these physical phenomena. In this presentation, we describe a new approach for high-efficiency water desalination based on surface-engineered porous materials. This approach is especially relevant for promising technologies such as nanofiltration and membrane distillation, which offers promising advantages over traditional desalination technologies using mesoporous membranes that are only permeable to pure water vapor. More accurate molecular modeling of mesoporous and nanoporous materials represents a key step towards efficient large-scale treatment of seawater. Results regarding the effect of pore properties (surface texture, morphology, density, tortuosity) on desired performance characteristics such as ion selectivity, maximal water flux and energy requirements will be presented.

  17. A highly efficient design strategy for regression with outcome pooling. (United States)

    Mitchell, Emily M; Lyles, Robert H; Manatunga, Amita K; Perkins, Neil J; Schisterman, Enrique F


    The potential for research involving biospecimens can be hindered by the prohibitive cost of performing laboratory assays on individual samples. To mitigate this cost, strategies such as randomly selecting a portion of specimens for analysis or randomly pooling specimens prior to performing laboratory assays may be employed. These techniques, while effective in reducing cost, are often accompanied by a considerable loss of statistical efficiency. We propose a novel pooling strategy based on the k-means clustering algorithm to reduce laboratory costs while maintaining a high level of statistical efficiency when predictor variables are measured on all subjects, but the outcome of interest is assessed in pools. We perform simulations motivated by the BioCycle study to compare this k-means pooling strategy with current pooling and selection techniques under simple and multiple linear regression models. While all of the methods considered produce unbiased estimates and confidence intervals with appropriate coverage, pooling under k-means clustering provides the most precise estimates, closely approximating results from the full data and losing minimal precision as the total number of pools decreases. The benefits of k-means clustering evident in the simulation study are then applied to an analysis of the BioCycle dataset. In conclusion, when the number of lab tests is limited by budget, pooling specimens based on k-means clustering prior to performing lab assays can be an effective way to save money with minimal information loss in a regression setting. Copyright © 2014 John Wiley & Sons, Ltd.

  18. Miniature, high efficiency transducers for use in ultrasonic flow meters (United States)

    Saikia, Meghna

    This thesis is concerned with the development of a new type of miniature, high efficiency transducer for use in ultrasonic flow meters. The proposed transducer consists of a thin plate of a suitable piezoelectric material on which an inter-digital transducer is fabricated for the generation and detection of plate acoustic waves. When immersed in a fluid medium, this device can convert energy from plate acoustic waves (PAWs) into bulk acoustic waves (BAWs) and vice versa. It is shown that this mode coupling principle can be used to realize efficient transducers for use in ultrasonic flow meters. This transducer can be mounted flush with the walls of the pipe through which fluid is flowing, resulting in minimal disturbance of fluid flow. A prototype flow cell using these transducers has been designed and fabricated. The characteristics of this device have been measured over water flow rates varying from 0 to 7.5 liters per minute and found to be in good agreement with theory. Another attractive property of the new transducers is that they can be used to realize remotely read, passive, wireless flow meters. Details of methods that can be used to develop this wireless capability are described. The research carried out in this thesis has applications in several other areas such as ultrasonic nondestructive evaluation (NDE), noncontact or air coupled ultrasonics, and for developing wireless capability in a variety of other acoustic wave sensors.

  19. High efficiency control of a grid-connected PV converter

    Energy Technology Data Exchange (ETDEWEB)

    Balogh, A.; Varjasi, I. [Budapest Univ. of Technology and Economics, Budapest (Hungary). Dept. of Automation and Applied Informatics; Bilau, Z.T. [Budapest Goldmann Gy, Budapest (Hungary)


    Core losses in photovoltaic (PV) grid-connected systems are often caused by ripple currents that decrease efficiency at low power rates. This paper discussed a control method designed to decrease the ripple current in the AC inductance of DC-AC converter filters. The control method used a 3-state control method with high on, low on, and off channels. The method used an algorithm developed for single phase converters and only required a modification of existing 2-state control methods. The 3-state control was applied when the stationary-state current of the output inductance reached zero. Degrees of freedom were then added to the control system. The insulated gate bipolar transistor (IGBT) was controlled only in relation to the direction of the current reference in order to create a discontinuous current mode. The rippled current increased according to a square root function of time until the current of the continuous mode was reached. The harmonic content of the output current became significant at smaller loads. Experiments were conducted on an frequency converter with a nominal power of 10 kW and a switching frequency of 16.5 kHz. Results of the experiments were compared with results obtained using a traditional current control device. The proposed control method increased the efficiency of the converter during periods of low radiation. 17 refs., 1 tab., 11 figs.

  20. High efficiency high step-up DC/DC converters - a review

    National Research Council Canada - National Science Library

    Tomaszuk, A; Krupa, A


    .... This review is focused on high efficiency step-up DC/DC converters with high voltage gain. The differentiation is based on the presence or lack of galvanic isolation. A comparison and discussion of different DC/DC step-up topologies will be performed across number of parameters and presented in this paper.

  1. High Efficiency, High Linearity, Switch Mode Power Amplifiers for Varying envelop Signal Applications

    DEFF Research Database (Denmark)

    Tong, Tian; Sira, Daniel; Nielsen, Michael


    using switch-mode power amplifier aided by various linearization techniques can present a feasible way to achieve both high linearity and high power efficiency. In this paper two different implementations of the switch-mode power amplifier a re p resented for varying envelop applications: the RF pulse...

  2. Flexibility of DNA/PNA, DNA/LNA, DNA/RNA hybrids measured with a nanoscale transducer (United States)

    Zhan, Yilin; Zocchi, Giovanni


    We report a new application for a previously introduced enzyme-DNA supramolecular construct, as a method to assess bending stiffness of short (∼10 nm long) synthetic nucleic acids. We obtain the first measurements of bending elasticity for DNA/PNA and DNA/LNA hybrids, and also assess the DNA/RNA hybrid. In order of increasing bending stiffness, we find: DNA/RNA, DNA/DNA, DNA/LNA, DNA/PNA. The experiments also probe the nonlinear elasticity regime of the coupled enzyme-nucleic acid molecules. We find the measurements consistent with the existence of a softening transition in the mechanics of the enzyme. This previously proposed nonlinearity maybe a general property of the folded state of proteins.

  3. Thin Film Packaging Solutions for High Efficiency OLED Lighting Products

    Energy Technology Data Exchange (ETDEWEB)



    The objective of the 'Thin Film Packaging Solutions for High Efficiency OLED Lighting Products' project is to demonstrate thin film packaging solutions based on SiC hermetic coatings that, when applied to glass and plastic substrates, support OLED lighting devices by providing longer life with greater efficiency at lower cost than is currently available. Phase I Objective: Demonstrate thin film encapsulated working phosphorescent OLED devices on optical glass with lifetime of 1,000 hour life, CRI greater than 75, and 15 lm/W. Phase II Objective: Demonstrate thin film encapsulated working phosphorescent OLED devices on plastic or glass composite with 25 lm/W, 5,000 hours life, and CRI greater than 80. Phase III Objective: Demonstrate 2 x 2 ft{sup 2} thin film encapsulated working phosphorescent OLED with 40 lm/W, 10,000 hour life, and CRI greater than 85. This report details the efforts of Phase III (Budget Period Three), a fourteen month collaborative effort that focused on optimization of high-efficiency phosphorescent OLED devices and thin-film encapsulation of said devices. The report further details the conclusions and recommendations of the project team that have foundation in all three budget periods for the program. During the conduct of the Thin Film Packaging Solutions for High Efficiency OLED Lighting Products program, including budget period three, the project team completed and delivered the following achievements: (1) a three-year marketing effort that characterized the near-term and longer-term OLED market, identified customer and consumer lighting needs, and suggested prototype product concepts and niche OLED applications lighting that will give rise to broader market acceptance as a source for wide area illumination and energy conservation; (2) a thin film encapsulation technology with a lifetime of nearly 15,000 hours, tested by calcium coupons, while stored at 16 C and 40% relative humidity ('RH'). This encapsulation technology

  4. High Efficiency Electron-Laser Interactions in Tapered Helical Undulators (United States)

    Duris, Joseph Patrick

    Efficient coupling of relativistic electron beams with high power radiation lies at the heart of advanced accelerator and light source research and development. The inverse free electron laser is a stable accelerator capable of harnessing very high intensity laser electric fields to efficiently transfer large powers from lasers to electron beams. In this dissertation, we first present the theoretical framework to describe the interaction, and then apply our improved understanding of the IFEL to the design and numerical study of meter-long, GeV IFELs for compact light sources. The central experimental work of the dissertation is the UCLA BNL helical inverse free electron laser experiment at the Accelerator Test Facility in Brookhaven National Laboratory which used a strongly tapered 54cm long, helical, permanent magnet undulator and a several hundred GW CO2 laser to accelerate electrons from 52 to 106MeV, setting new records for inverse free electron laser energy gain (54MeV) and average accelerating gradient (100MeV/m). The undulator design and fabrication as well as experimental diagnostics are presented. In order to improve the stability and quality of the accelerated electron beam, we redesigned the undulator for a slightly reduced output energy by modifying the magnet gap throughout the undulator, and we used this modified undulator to demonstrated capture of >25% of the injected beam without prebunching. In the study of heavily loaded GeV inverse free electron lasers, we show that a majority of the power may be transferred from a laser to the accelerated electron beam. Reversing the process to decelerate high power electron beams, a mechanism we refer to as tapering enhanced stimulated superradiant amplification, offers a clear path to high power light sources. We present studies of radiation production for a wide range of wavelengths (10mum, 13nm, and 0.3nm) using this method and discuss the design for a deceleration experiment using the same undulator used

  5. Dimensioning storage and computing clusters for efficient High Throughput Computing

    CERN Multimedia

    CERN. Geneva


    Scientific experiments are producing huge amounts of data, and they continue increasing the size of their datasets and the total volume of data. These data are then processed by researchers belonging to large scientific collaborations, with the Large Hadron Collider being a good example. The focal point of Scientific Data Centres has shifted from coping efficiently with PetaByte scale storage to deliver quality data processing throughput. The dimensioning of the internal components in High Throughput Computing (HTC) data centers is of crucial importance to cope with all the activities demanded by the experiments, both the online (data acceptance) and the offline (data processing, simulation and user analysis). This requires a precise setup involving disk and tape storage services, a computing cluster and the internal networking to prevent bottlenecks, overloads and undesired slowness that lead to losses cpu cycles and batch jobs failures. In this paper we point out relevant features for running a successful s...

  6. Highly efficient optical parametric generation in proton exchanged PPLN waveguides

    CERN Document Server

    Chanvillard, L; Baldi, P; De Micheli, M; Ostrowsky, D B; Huang, L; Bamford, G


    Summary form only given. Parametric fluorescence, amplification, and oscillation in PPLN waveguides have already been demonstrated. In all previous experiments, the measured efficiencies were smaller than the theoretically predicted values since the waveguide fabrication process utilized, annealed proton exchange (APE) can reduce or even destroy the nonlinear coefficient and/or the periodic domain orientation in a portion of the guiding structure. In the experiment reported here, we used a 2 cm long, Z-cut PPLN with a 18 mu m domain inversion period. The waveguides are created using a direct proton exchange process in a highly diluted melt, which induces no crystallographic phase transition. This allows preserving both the nonlinear coefficient and the domain orientation while fully benefiting from the power confinement associated with the guided wave configuration. (4 refs).

  7. High efficiency solid-state sensitized heterojunction photovoltaic device

    KAUST Repository

    Wang, Mingkui


    The high molar extinction coefficient heteroleptic ruthenium dye, NaRu(4,4′-bis(5-(hexylthio)thiophen-2-yl)-2,2′-bipyridine) (4-carboxylic acid-4′-carboxylate-2,2′-bipyridine) (NCS) 2, exhibits certified 5% electric power conversion efficiency at AM 1.5 solar irradiation (100 mW cm-2) in a solid-state dye-sensitized solar cell using 2,2′,7,7′-tetrakis-(N,N-di-pmethoxyphenylamine)-9, 9′-spirobifluorene (spiro-MeOTAD) as the organic hole-transporting material. This demonstration elucidates a class of photovoltaic devices with potential for low-cost power generation. © 2010 Elsevier Ltd. All rights reserved.

  8. Non-equilibrium Microwave Plasma for Efficient High Temperature Chemistry. (United States)

    van den Bekerom, Dirk; den Harder, Niek; Minea, Teofil; Gatti, Nicola; Linares, Jose Palomares; Bongers, Waldo; van de Sanden, Richard; van Rooij, Gerard


    A flowing microwave plasma based methodology for converting electric energy into internal and/or translational modes of stable molecules with the purpose of efficiently driving non-equilibrium chemistry is discussed. The advantage of a flowing plasma reactor is that continuous chemical processes can be driven with the flexibility of startup times in the seconds timescale. The plasma approach is generically suitable for conversion/activation of stable molecules such as CO2, N2 and CH4. Here the reduction of CO2 to CO is used as a model system: the complementary diagnostics illustrate how a baseline thermodynamic equilibrium conversion can be exceeded by the intrinsic non-equilibrium from high vibrational excitation. Laser (Rayleigh) scattering is used to measure the reactor temperature and Fourier Transform Infrared Spectroscopy (FTIR) to characterize in situ internal (vibrational) excitation as well as the effluent composition to monitor conversion and selectivity.

  9. Synthesis of silicon quantum dots showing high quantum efficiency. (United States)

    Cho, Bomin; Baek, Sangsoo; Woo, Hee-Gweon; Sohn, Honglae


    Quantum efficiencies of Si quantum dots (QDs) have been investigated from the reaction of magnesium silicide and ammonium chloride. The change of quantum yield and optical characterization of Si QDs are measured depending on the reaction time. Highly luminescent Si QDs were obtained as the reaction time increased. Absorption measurement indicated that the Si QDs consisted of only silicon and hydrogen atom. Optical characterizations of Si QDs were measured by UV-Vis and PL spectroscopy. The size distribution and orientation of Si QDs were measured by TEM and XRD. TEM image displays the spherical Si QDs with the size of 3-4 nm. As the reaction time increased, Si QDs grew and their emission wavelength shifted to the longer wavelength. The monotonic shift of the PL as a function of excitation wavelength resulted in the excitation of different sizes of QDs that had different optical transition energies. Photoluminescence quantum yields exceeding 60% have been achieved.

  10. A High-Efficiency Diode-Clamped Linear Amplifier (United States)

    Fujita, Hideaki

    This paper proposes a new power converter without any switching operation, which works as a linear amplifier. The main circuit of the proposed converter consists of series-connected MOSFETs, series-multi dc power supplies and clamping diodes. The circuit configuration is similar to a diode-clamped multi-level inverter, except for using complementary power devices, which are n- and p-channel MOSFETs. One of the series-connected MOSFETs operates in an active state just like a linear amplifier, while the other MOSFETs operate in on or off states like an inverter circuit. As a result, the proposed converter achieves an acceptable efficiency as high as 90% without any ripples nor harmonics caused by switching operation. Experimental results demonstrate that the proposed converter has capability of driving a 2.2-kW three-phase induction motor.

  11. Highly efficient and controllable method to fabricate ultrafine metallic nanostructures

    Energy Technology Data Exchange (ETDEWEB)

    Cai, Hongbing; Zhang, Kun; Pan, Nan, E-mail:, E-mail:; Luo, Yi; Wang, Xiaoping, E-mail:, E-mail: [Hefei National Laboratory for Physical Sciences at the Microscale, University of Science & Technology of China, Hefei 230026 (China); Yu, Xinxin [Physics school, Anhui University, Hefei Anhui 230601 China (China); Tian, Yangchao [National Synchrotron Radiation Laboratory, University of Science & Technology of China, Hefei 230027 (China)


    We report a highly efficient, controllable and scalable method to fabricate various ultrafine metallic nanostructures in this paper. The method starts with the negative poly-methyl-methacrylate (PMMA) resist pattern with line-width superior to 20 nm, which is obtained from overexposing of the conventionally positive PMMA under a low energy electron beam. The pattern is further shrunk to sub-10 nm line-width through reactive ion etching. Using the patter as a mask, we can fabricate various ultrafine metallic nanostructures with the line-width even less than 10 nm. This ion tailored mask lithography (ITML) method enriches the top-down fabrication strategy and provides potential opportunity for studying quantum effects in a variety of materials.

  12. Leaks in nuclear grade high efficiency aerosol filters

    Energy Technology Data Exchange (ETDEWEB)

    Scripsick, Ronald Clyde [Univ. of California, Davis, CA (United States)


    Nuclear grade high efficiency aerosol filters, also known as high efficiency particulate air (HEPA) filters, are commonly used in air cleaning systems for removal of hazardous aerosols. Performance of the filter units is important in assuring health and environmental protection. The filter units are constructed from pleated packs of fiberglass filter media sealed into rigid frames. Results of previous studies on such filter units indicate that their performance may not be completely predicted by ideal performance of the fibrous filter media. In this study, departure from ideal performance is linked to leaks existing in filter units and overall filter unit performance is derived from independent performance of the individual filter unit components. The performance of 14 nuclear grade HEPA filter units (size 1, 25 cfm) with plywood frames was evaluated with a test system that permitted independent determination of penetration as a function of particle size for the whole filter unit, the filter unit frame, and the filter media pack. Tests were performed using a polydisperse aerosol of di-2-ethylhexyl phthalate with a count median diameter of 0.2 {mu}m and geometric standard deviation of 1.6. Flow rate and differential pressure were controlled from 1% to 100% of design values. Particle counts were made upstream and downstream of the filter unit with an optical particle counter (OPC). The OPC provided count information in 28 size channels over the particle diameter range from 0.1 to 0.7 μm. Results provide evidence for a two component leak model of filler unit performance with: (1) external leaks through filter unit frames, and (2) internal leaks through defects in the media and through the seal between the media pack and frame. For the filter units evaluated, these leaks dominate overall filter unit performance over much of the flow rate and particle size ranges tested.

  13. ?Intrinsic? correlations and their temporal evolutions between winter-time PNA/EPW and winter drought in the west United States


    Lin Piao; Zuntao Fu; Naiming Yuan


    In this study, relations between winter-time Pacific-Northern America pattern (PNA)/East Pacific wave-train (EPW) and winter-time drought in the west United States over the period of 1951?2010 are analyzed. Considering traditional Pearson?s Correlation Coefficient can be influenced by non-stationarity and nonlinearity, a recently proposed method, Detrended Partial-Cross-Correlation Analysis (DPCCA) is applied. With DPCCA, we analyzed the ?intrinsic? correlations between PNA/EPW and the winter...

  14. Highly Efficient Fiber Lasers for Wireless Power Transmission Project (United States)

    National Aeronautics and Space Administration — We propose to develop ytterbium (Yb) fiber lasers with an electrical-to-optical efficiency of nominally 64% by directly coupling 80%-efficient diode lasers with Yb...

  15. γPNA FRET Pair Miniprobes for Quantitative Fluorescent In Situ Hybridization to Telomeric DNA in Cells and Tissue

    Directory of Open Access Journals (Sweden)

    Alexander Orenstein


    Full Text Available Measurement of telomere length by fluorescent in situ hybridization is widely used for biomedical and epidemiological research, but there has been relatively little development of the technology in the 20 years since it was first reported. This report describes the use of dual gammaPNAPNA probes that hybridize at alternating sites along a telomere and give rise to Förster resonance energy transfer (FRET signals. Bright staining of telomeres is observed in nuclei, chromosome spreads and tissue samples. The use of FRET detection also allows for elimination of wash steps, normally required to remove unhybridized probes that would contribute to background signals. We found that these wash steps can diminish the signal intensity through the removal of bound, as well as unbound probes, so eliminating these steps not only accelerates the process but also enhances the quality of staining. Thus, γPNA FRET pairs allow for brighter and faster staining of telomeres in a wide range of research and clinical formats.

  16. Transcolonic Perirectal NOTES Access (PNA): A feasibility study with survival in swine model. (United States)

    Oliveira, André L A; Zorron, Ricardo; Oliveira, Flavio M M DE; Santos, Marcelo B Dos; Scheffer, Jussara P; Rios, Marcelo; Antunes, Fernanda


    Transrectal access still has some unsolved issues such as spatial orientation, infection, access and site closure. This study presents a simple technique to perform transcolonic access with survival in a swine model series. A new technique for NOTES perirectal access to perform retroperitoneoscopy, peritoneoscopy, liver and lymphnode biopsies was performed in 6 pigs, using Totally NOTES technique. The specimens were extracted transanally. The flexible endoscope was inserted through a posterior transmural incision and the retrorectal space. Cultures of bacteria were documented for the retroperitoneal space and intra abdominal cavity after 14 days. Rectal site was closed using non-absorbable sutures. There was no bowel cleansing, nor preoperative fasting. The procedures were performed in 6 pigs through transcolonic natural orifice access using available endoscopic flexible instruments. All animals survived 14 days without complications, and cultures were negative. Histopathologic examination of the rectal closure site showed adequate healing of suture line and no micro abscesses. The results of feasibility and safety of experimental Transcolonic NOTES potentially brings new frontiers and future wider applications for minimally invasive surgery. The treatment of colorectal, abdominal and retroperitoneal diseases through a flexible Perirectal NOTES Access (PNA) is a promising new approach.

  17. Efficiency of High Order Spectral Element Methods on Petascale Architectures

    KAUST Repository

    Hutchinson, Maxwell


    High order methods for the solution of PDEs expose a tradeoff between computational cost and accuracy on a per degree of freedom basis. In many cases, the cost increases due to higher arithmetic intensity while affecting data movement minimally. As architectures tend towards wider vector instructions and expect higher arithmetic intensities, the best order for a particular simulation may change. This study highlights preferred orders by identifying the high order efficiency frontier of the spectral element method implemented in Nek5000 and NekBox: the set of orders and meshes that minimize computational cost at fixed accuracy. First, we extract Nek’s order-dependent computational kernels and demonstrate exceptional hardware utilization by hardware-aware implementations. Then, we perform productionscale calculations of the nonlinear single mode Rayleigh-Taylor instability on BlueGene/Q and Cray XC40-based supercomputers to highlight the influence of the architecture. Accuracy is defined with respect to physical observables, and computational costs are measured by the corehour charge of the entire application. The total number of grid points needed to achieve a given accuracy is reduced by increasing the polynomial order. On the XC40 and BlueGene/Q, polynomial orders as high as 31 and 15 come at no marginal cost per timestep, respectively. Taken together, these observations lead to a strong preference for high order discretizations that use fewer degrees of freedom. From a performance point of view, we demonstrate up to 60% full application bandwidth utilization at scale and achieve ≈1PFlop/s of compute performance in Nek’s most flop-intense methods.

  18. High-precision efficiency calibration of a high-purity co-axial germanium detector

    Energy Technology Data Exchange (ETDEWEB)

    Blank, B., E-mail: [Centre d' Etudes Nucléaires de Bordeaux Gradignan, UMR 5797, CNRS/IN2P3, Université de Bordeaux, Chemin du Solarium, BP 120, 33175 Gradignan Cedex (France); Souin, J.; Ascher, P.; Audirac, L.; Canchel, G.; Gerbaux, M.; Grévy, S.; Giovinazzo, J.; Guérin, H.; Nieto, T. Kurtukian; Matea, I. [Centre d' Etudes Nucléaires de Bordeaux Gradignan, UMR 5797, CNRS/IN2P3, Université de Bordeaux, Chemin du Solarium, BP 120, 33175 Gradignan Cedex (France); Bouzomita, H.; Delahaye, P.; Grinyer, G.F.; Thomas, J.C. [Grand Accélérateur National d' Ions Lourds, CEA/DSM, CNRS/IN2P3, Bvd Henri Becquerel, BP 55027, F-14076 CAEN Cedex 5 (France)


    A high-purity co-axial germanium detector has been calibrated in efficiency to a precision of about 0.15% over a wide energy range. High-precision scans of the detector crystal and γ-ray source measurements have been compared to Monte-Carlo simulations to adjust the dimensions of a detector model. For this purpose, standard calibration sources and short-lived online sources have been used. The resulting efficiency calibration reaches the precision needed e.g. for branching ratio measurements of super-allowed β decays for tests of the weak-interaction standard model.

  19. High power, high efficiency continuous-wave 808 nm laser diode arrays (United States)

    Wang, Zhenfu; Li, Te; Yang, Guowen; Song, Yunfei


    The continuous-wave 100 W-class 808 nm laser diode arrays with extremely high power conversion efficiency of 68% were reported at the heatsink temperature of 25 °C. To the best of our knowledge, this was the highest power conversion efficiency at continuous-wave 106 W 808 nm laser diode array with 50% fill factor so far. An asymmetric broad waveguide epitaxial structure with very low internal optical loss of 0.5 cm-1 was presented. In order to improve the efficiency, various fill factor devices were studied. The 50 W laser diode array with 30% fill factoir and 1.0 mm cavity length demonstrated power conversion efficiency of 71% at heatsink temperature of 15 °C.

  20. Aerodynamic design considerations for efficient high-lift supersonic wings (United States)

    Miller, D. S.; Wood, R. M.


    A previously developed technique for selecting a design space for efficient supersonic wings is reviewed; this design-space concept is expanded to include thickness and camber effects and is evaluated for cambered wings at high-lift conditions. The original design-space formulation was based on experimental upper-surface and lower-surface normal-force characteristics for flat, uncambered delta wings; it is shown that these general characteristics hold for various thickness distributions and for various amounts of leading-edge camber. The original design-space formulation was also based on the assumption that the combination of Mach number and leading-edge sweep which would produce an equal division of flat-wing lift between the upper and lower surface would also be the proper combination to give the best cambered-wing performance. Using drag-due-to-lift factor as a measure of performance, for high-lift conditions cambered-wing performance is shown to significantly increase as conditions approach the design space; this correlation is demonstrated for both subcritical and supercritical flows.

  1. High efficiency video coding (HEVC) algorithms and architectures

    CERN Document Server

    Budagavi, Madhukar; Sullivan, Gary


    This book provides developers, engineers, researchers and students with detailed knowledge about the High Efficiency Video Coding (HEVC) standard. HEVC is the successor to the widely successful H.264/AVC video compression standard, and it provides around twice as much compression as H.264/AVC for the same level of quality. The applications for HEVC will not only cover the space of the well-known current uses and capabilities of digital video – they will also include the deployment of new services and the delivery of enhanced video quality, such as ultra-high-definition television (UHDTV) and video with higher dynamic range, wider range of representable color, and greater representation precision than what is typically found today. HEVC is the next major generation of video coding design – a flexible, reliable and robust solution that will support the next decade of video applications and ease the burden of video on world-wide network traffic. This book provides a detailed explanation of the various parts ...

  2. Energy reduction using biofiltration in a highly efficient residential home (United States)

    Rodgers, Kevin L.

    The objective of this research was to design, demonstrate, and monitor the Biowall; a novel system for improving indoor air quality in a residential building, which has the potential to save energy compared to traditional air quality control. The Biowall was integrated into the heating, ventilation, and air-condition system of a high performance home and utilized plants as a passive filter system to remove volatile organic compounds from the interior space of the home. The testing environment in this study was a 984 square foot efficient residential home constructed for the U.S. Department of Energy Solar Decathlon 2011 competition. A number of sensors were installed in the home to monitor the operation of the wall including temperature, relative humidity, carbon dioxide, and total volatile organic compound (TVOC) sensors. The main outcomes of the project included the design and construction of a test platform for the current study and future research, energy results that showed as high as 160% energy savings over a 1 week test period and $170 per year in cost savings versus a traditional ventilation strategy, and lessons learned and suggestions for future research.

  3. Highly Efficient Domain Walls Injection in Perpendicular Magnetic Anisotropy Nanowire. (United States)

    Zhang, S F; Gan, W L; Kwon, J; Luo, F L; Lim, G J; Wang, J B; Lew, W S


    Electrical injection of magnetic domain walls in perpendicular magnetic anisotropy nanowire is crucial for data bit writing in domain wall-based magnetic memory and logic devices. Conventionally, the current pulse required to nucleate a domain wall is approximately ~10(12) A/m(2). Here, we demonstrate an energy efficient structure to inject domain walls. Under an applied electric potential, our proposed Π-shaped stripline generates a highly concentrated current distribution. This creates a highly localized magnetic field that quickly initiates the nucleation of a magnetic domain. The formation and motion of the resulting domain walls can then be electrically detected by means of Ta Hall bars across the nanowire. Our measurements show that the Π-shaped stripline can deterministically write a magnetic data bit in 15 ns even with a relatively low current density of 5.34 × 10(11) A/m(2). Micromagnetic simulations reveal the evolution of the domain nucleation - first, by the formation of a pair of magnetic bubbles, then followed by their rapid expansion into a single domain. Finally, we also demonstrate experimentally that our injection geometry can perform bit writing using only about 30% of the electrical energy as compared to a conventional injection line.

  4. Graphene Oxide Interlayers for Robust, High-Efficiency Organic Photovoltaics

    Energy Technology Data Exchange (ETDEWEB)

    Murray, Ian P.; Lou, Sylvia J.; Cote, Laura J.; Loser, Stephen; Kadleck, Cameron J.; Xu, Tao; Szarko, Jodi M.; Rolczynski, Brian S.; Johns, James E.; Huang, Jiaxing; Yu, Luping; Chen, Lin X.; Marks, Tobin J.; Hersam, Mark C. (NWU)


    Organic photovoltaic (OPV) materials have recently garnered significant attention as enablers of high power conversion efficiency (PCE), low-cost, mechanically flexible solar cells. Nevertheless, further understanding-based materials developments will be required to achieve full commercial viability. In particular, the performance and durability of many current generation OPVs are limited by poorly understood interfacial phenomena. Careful analysis of typical OPV architectures reveals that the standard electron-blocking layer, poly-3,4-ethylenedioxy-thiophene:poly(styrene sulfonate) (PEDOT:PSS), is likely a major factor limiting the device durability and possibly performance. Here we report that a single layer of electronically tuned graphene oxide is an effective replacement for PEDOT:PSS and that it significantly enhances device durability while concurrently templating a performance-optimal active layer {pi}-stacked face-on microstructure. Such OPVs based on graphene oxide exhibit PCEs as high as 7.5% while providing a 5x enhancement in thermal aging lifetime and a 20x enhancement in humid ambient lifetime versus analogous PEDOT:PSS-based devices.

  5. Porous germanene as a highly efficient gas separation membrane. (United States)

    Bian, Ang; Dai, Yafei; Yang, Jinlong


    Using a gas separation membrane as a simple gas separation device has an obvious advantage because of the low energy consumption and pollution-free manufacturing. The first-principles calculations used in this work show that germanene with its divacancy is an excellent material for use as a hydrogen (H2) and helium (He) separation membrane, and that it displays an even better competitive advantage than porous graphene and porous silicene. Porous germanene with its divacancy is chemically inert to gas molecules, because it lacks additional atoms to protect the edged dangling germanium atoms in defects, and thus shows great advantages for gas separation over previously prepared graphene. The energy barriers to H2 and He penetrating porous germanene are quite low, and the permeabilities to H2 and He are high. Furthermore, the selectivities of porous germanene for H2 and He relative to other gas molecules are high, up to 1031 and 1027, respectively, which are superior to those of porous graphene (1023) and porous silicene (1013); thus the separation efficiency of porous germanene is much higher than that of porous graphene and porous silicene. Therefore, germanene is a favorable candidate as a gas separation membrane material. At the same time, the successful synthesis of germanene in the laboratory means that it is possible to use it in real applications.

  6. A novel endolysin disrupts Streptococcus suis with high efficiency. (United States)

    Ji, Wenhui; Huang, Qingqing; Sun, Liang; Wang, Hengan; Yan, Yaxian; Sun, Jianhe


    Streptococcus suis serotype 2 (S. suis 2) is a zoonotic pathogen that exhibits high-level resistance and multi-drug resistance to classic antibiotics and causes serious human casualties and heavy economic losses in the swine industry worldwide. Therefore, alternative therapies or novel antibacterial agents need to be developed to combat this pathogen. A novel endolysin derived from the S. suis temperate phage phi7917, termed Ly7917, was identified, which had broad lytic activity against S. suis type 1, 2, 7 and 9. Ly7917 consisted of an N-terminal cysteine, histidine-dependent amidohydrolases/peptidase catalytic domain and C-terminal SH3b cell wall binding domain. The endolysin maintained activity at high pH and its catalytic activity could be improved by addition of 10 μM 1.5 mM Ca(2+). In animal studies, 90% of BALB/c mice challenged with typical virulent strain HA9801 of S. suis 2 were protected by Ly7917 treatment. The bacterial load in the blood of HA9801-challenged mice was efficiently reduced almost 50% by Ly7917 while that of penicillin-G-treated mice kept almost unchanged. Our data suggest that Ly7917 may be an alternative therapeutic agent for infections caused by virulent S. suis strains. © FEMS 2015. All rights reserved. For permissions, please e-mail:

  7. Ehenge: marginalized soil with high water use efficiency (United States)

    Prudat, Brice; Bloemertz, Lena; Kuhn, Nikolaus J.


    Ehenge is a soil that has been described by the communities of North-Central Namibia during different studies. Farmers consider this soil as nutrient-poor with a deep loose sand layer over a hardpan, called olumha. Despite its low nutrient content, this soil is usually cultivated because it holds water for a longer period than some more nutrient-rich soils. This characteristic is an advantage during growing season with scarce rains. It has been described so far as a (hypoluvic hyperalbic) Arenosol. The sequence of characteristic horizons is as follows: sandy A and E; thin accumulation horizon Bt on top of a Bg horizon. The latter is important for water storage during dry periods (as shown by water soil monitoring data). Management practices for this soil type are very different from other Arenosols, because the water dynamics are very specific, with high percolation rates combined with a high risk of waterlogging. The evolution of agriculture in North-Central Namibia will determine the future use and preservation of these soils, as the presence of hardpan is considered to be a limiting factor for agricultural development. The author demonstrates that this soil has a large potential for agricultural water use efficiency, in an area with very limited water resources and that might face longer dry period as an effect of climate change.

  8. High Efficiency, Ultra-Low Emission, Integrated Process Heater System

    Energy Technology Data Exchange (ETDEWEB)

    Mason, Howard; Boral, Anindya; Chhotray, San; Martin, Matthew


    The team of TIAX LLC, ExxonMobil Research and Engineering Company, and Callidus Technologies, LLC conducted a six-year program to develop an ultra-low emission process heater burner and an advanced high efficiency heater design. This project addresses the critical need of process heater operators for reliable, economical emission reduction technologies to comply with stringent emission regulations, and for heater design alternatives that reduce process heater energy requirements without significant cost increase. The key project targets were NOx emissions of 10 ppm (@ 3% O2), and a heater thermal efficiency of 95 percent. The ultra low NOx burner was developed through a series of pilot-scale and field tests combined with computational fluid dynamic modeling to arrive at simultaneous low emissions and suitable flame shape and stability. Pilot scale tests were run at TIAX, at the 2 MMBtu/hr scale, and at Callidus at 8 MMBtu/hr. The full scale burner was installed on a 14 burner atmospheric pipestill furnace at an ExxonMobil refinery. A variety of burner configurations, gas tips and flame stabilizers were tested to determine the lowest emissions with acceptable flame shape and stability. The resulting NOx emissions were 22 ppm on average. Starting in 2001, Callidus commercialized the original ultra low NOx burner and made subsequent design improvements in a series of commercial burners evolving from the original concept and/or development. Emissions in the field with the ultra low-NOx burner over a broad spectrum of heater applications have varied from 5 ppm to 30 ppm depending on heater geometry, heater service, fuel and firing capacity. To date, 1550 of the original burners, and 2500 of subsequent generation burners have been sold by Callidus. The advanced heater design was developed by parametric evaluations of a variety of furnace and combustion air preheater configurations and technologies for enhancing convective and radiative heat transfer. The design evolution

  9. Progress of High Efficiency Centrifugal Compressor Simulations Using TURBO (United States)

    Kulkarni, Sameer; Beach, Timothy A.


    Three-dimensional, time-accurate, and phase-lagged computational fluid dynamics (CFD) simulations of the High Efficiency Centrifugal Compressor (HECC) stage were generated using the TURBO solver. Changes to the TURBO Parallel Version 4 source code were made in order to properly model the no-slip boundary condition along the spinning hub region for centrifugal impellers. A startup procedure was developed to generate a converged flow field in TURBO. This procedure initialized computations on a coarsened mesh generated by the Turbomachinery Gridding System (TGS) and relied on a method of systematically increasing wheel speed and backpressure. Baseline design-speed TURBO results generally overpredicted total pressure ratio, adiabatic efficiency, and the choking flow rate of the HECC stage as compared with the design-intent CFD results of Code Leo. Including diffuser fillet geometry in the TURBO computation resulted in a 0.6 percent reduction in the choking flow rate and led to a better match with design-intent CFD. Diffuser fillets reduced annulus cross-sectional area but also reduced corner separation, and thus blockage, in the diffuser passage. It was found that the TURBO computations are somewhat insensitive to inlet total pressure changing from the TURBO default inlet pressure of 14.7 pounds per square inch (101.35 kilopascals) down to 11.0 pounds per square inch (75.83 kilopascals), the inlet pressure of the component test. Off-design tip clearance was modeled in TURBO in two computations: one in which the blade tip geometry was trimmed by 12 mils (0.3048 millimeters), and another in which the hub flow path was moved to reflect a 12-mil axial shift in the impeller hub, creating a step at the hub. The one-dimensional results of these two computations indicate non-negligible differences between the two modeling approaches.

  10. Highly Efficient InGaN-Based Solar Cells for High Intensity and High Temperature Operation Project (United States)

    National Aeronautics and Space Administration — In this SBIR Phase I program, we propose to fabricate high-efficiency and radiation hard solar cells based on InGaN material system that can cover the whole solar...

  11. The Designs of High Efficiency Launcher of Quasi-Optical Mode Converter for High Power Gyrotrons (United States)

    Minami, R.; Kasugai, A.; Takahashi, K.; Kobayashi, N.; Mitsunaka, Y.; Sakamoto, K.


    A high efficiency launcher of quasi-optical (QO) mode converters for high power gyrotrons have been designed and tested. A helical cut launcher radiates the RF power via its straight cut onto the first phase correcting mirror. The launchers have been optimized for the TE31.8 mode at 170 GHz and TE22.6 mode at 110 GHz by numerically optimizing a launcher surface. The helical cut of the launcher has been optimized by taking the taper angle into account. Further more, the amplitude of the surface perturbation have been optimized for improved focusing in order to reduce the diffraction losses at the helical cut. Low power measurement shows a good agreement with the design. High efficiency characteristics of the design have also been calculated on the assumption of frequency downshift due to the thermal expansion of the cavity and stepwise frequency tuning by changing the operating mode. Besides, the possibility of high efficiency launcher for higher mode is discussed, and these results give the prospect to high efficiency long pulse gyrotrons.

  12. High-Efficiency Nitride-Based Solid-State Lighting

    Energy Technology Data Exchange (ETDEWEB)

    Paul T. Fini; Shuji Nakamura


    In this final technical progress report we summarize research accomplished during Department of Energy contract DE-FC26-01NT41203, entitled ''High-Efficiency Nitride-Based Solid-State Lighting''. Two teams, from the University of California at Santa Barbara (Principle Investigator: Dr. Shuji Nakamura) and the Lighting Research Center at Rensselaer Polytechnic Institute (led by Dr. N. Narendran), pursued the goals of this contract from thin film growth, characterization, and packaging/luminaire design standpoints. The UCSB team initially pursued the development of blue gallium nitride (GaN)-based vertical-cavity surface-emitting lasers, as well as ultraviolet GaN-based light emitting diodes (LEDs). In Year 2, the emphasis shifted to resonant-cavity light emitting diodes, also known as micro-cavity LEDs when extremely thin device cavities are fabricated. These devices have very directional emission and higher light extraction efficiency than conventional LEDs. Via the optimization of thin-film growth and refinement of device processing, we decreased the total cavity thickness to less than 1 {micro}m, such that micro-cavity effects were clearly observed and a light extraction efficiency of over 10% was reached. We also began the development of photonic crystals for increased light extraction, in particular for so-called ''guided modes'' which would otherwise propagate laterally in the device and be re-absorbed. Finally, we pursued the growth of smooth, high-quality nonpolar a-plane and m-plane GaN films, as well as blue light emitting diodes on these novel films. Initial nonpolar LEDs showed the expected behavior of negligible peak wavelength shift with increasing drive current. M-plane LEDs in particular show promise, as unpackaged devices had unsaturated optical output power of {approx} 3 mW at 200 mA drive current. The LRC's tasks were aimed at developing the subcomponents necessary for packaging UCSB's light

  13. High efficiency digital cooler electronics for aerospace applications (United States)

    Kirkconnell, C. S.; Luong, T. T.; Shaw, L. S.; Murphy, J. B.; Moody, E. A.; Lisiecki, A. L.; Ellis, M. J.


    Closed-cycle cryogenic refrigerators, or cryocoolers, are an enabling technology for a wide range of aerospace applications, mostly related to infrared (IR) sensors. While the industry focus has tended to be on the mechanical cryocooler thermo mechanical unit (TMU) alone, implementation on a platform necessarily consists of the combination of the TMU and a mating set of command and control electronics. For some applications the cryocooler electronics (CCE) are technologically simple and low cost relative to the TMU, but this is not always the case. The relative cost and complexity of the CCE for a space-borne application can easily exceed that of the TMU, primarily due to the technical constraints and cost impacts introduced by the typical space radiation hardness and reliability requirements. High end tactical IR sensor applications also challenge the state of the art in cryocooler electronics, such as those for which temperature setpoint and frequency must be adjustable, or those where an informative telemetry set must be supported, etc. Generally speaking for both space and tactical applications, it is often the CCE that limits the rated lifetime and reliability of the cryocooler system. A family of high end digital cryocooler electronics has been developed to address these needs. These electronics are readily scalable from 10W to 500W output capacity; experimental performance data for nominally 25W and 100W variants are presented. The combination of a FPGA-based controller and dual H-bridge motor drive architectures yields high efficiency (>92% typical) and precision temperature control (+/- 30 mK typical) for a wide range of Stirling-class mechanical cryocooler types and vendors. This paper focuses on recent testing with the AIM INFRAROT-MODULE GmbH (AIM) SX030 and AIM SF100 cryocoolers.

  14. Designing and optimizing highly efficient grating for high-brightness laser based on spectral beam combining

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Ying-Ying, E-mail:, E-mail:; Zhao, Ya-Ping; Wang, Li-Rong; Zhang, Ling; Lin, Xue-Chun, E-mail:, E-mail: [Laboratory of All Solid State Light Sources, Institute of Semiconductors, Chinese Academy of Sciences, Beijing 100083 (China)


    A highly efficient nano-periodical grating is theoretically investigated for spectral beam combining (SBC) and is experimentally implemented for attaining high-brightness laser from a diode laser array. The rigorous coupled-wave analysis with the S matrix method is employed to optimize the parameters of the grating. According the optimized parameters, the grating is fabricated and plays a key role in SBC cavity. The diffraction efficiency of this grating is optimized to 95% for the output laser which is emitted from the diode laser array. The beam parameter product of 3.8 mm mrad of the diode laser array after SBC is achieved at the output power of 46.3 W. The optical-to-optical efficiency of SBC cavity is measured to be 93.5% at the maximum operating current in the experiment.

  15. Low Temperature Combustion Demonstrator for High Efficiency Clean Combustion

    Energy Technology Data Exchange (ETDEWEB)

    Ojeda, William de


    The project which extended from November 2005 to May of 2010 demonstrated the application of Low Temperature Combustion (LTC) with engine out NOx levels of 0.2 g/bhp-hr throughout the program target load of 12.6bar BMEP. The project showed that the range of loads could be extended to 16.5bar BMEP, therefore matching the reference lug line of the base 2007 MY Navistar 6.4L V8 engine. Results showed that the application of LTC provided a dramatic improvement over engine out emissions when compared to the base engine. Furthermore LTC improved thermal efficiency by over 5% from the base production engine when using the steady state 13 mode composite test as a benchmark. The key enablers included improvements in the air, fuel injection, and cooling systems made in Phases I and II. The outcome was the product of a careful integration of each component under an intelligent control system. The engine hardware provided the conditions to support LTC and the controller provided the necessary robustness for a stable combustion. Phase III provided a detailed account on the injection strategy used to meet the high load requirements. During this phase, the control strategy was implemented in a production automotive grade ECU to perform cycle-by-cycle combustion feedback on each of the engine cylinders. The control interacted on a cycle base with the injection system and with the Turbo-EGR systems according to their respective time constants. The result was a unique system that could, first, help optimize the combustion system and maintain high efficiency, and secondly, extend the steady state results to the transient mode of operation. The engine was upgraded in Phase IV with a Variable Valve Actuation system and a hybrid EGR loop. The impact of the more versatile EGR loop did not provide significant advantages, however the application of VVA proved to be an enabler to further extend the operation of LTC and gain considerable benefits in fuel economy and soot reduction. Finally

  16. High surface area aerogels for energy storage and efficiency (United States)

    Maloney, Ryan Patrick

    The dissertation is divided into two main chapters, each focused on a different application for aerogel. The first chapter concerns the development of silica aerogel for thermal insulation. It begins with initial characterization of a silica aerogel insulation for a next-generation Advanced Radioisotope Stirling Generator for space vehicles. While the aerogel as made performs well, it is apparent that further improvements in mechanical strength and durability are necessary. The chapter then continues with the exploration of chlorotrimethysilane surface modification, which somewhat surprisingly provides a drastic increase in mechanical properties, allowing the inherently brittle silica network to deform plastically to >80% strain. It is hypothesized that the hydrophobic surface groups reduce capillary forces during drying, lowering the number of microcracks that may form and weaken the gel. This surface modification scheme is then implemented in a fiber-reinforced, opacified aerogel insulation for a prototypical thermoelectric generator for automotive waste heat recovery. This is the first known report of aerogel insulation for thermoelectrics. The aerogel insulation is able to increase the efficiency of the thermoelectric generator by 40% compared with commercial high-temperature insulating wool. Unfortunately, the supercritical drying process adds significant cost to the aerogel insulation, limiting its commercial viability. The chapter then culminates in the development and characterization of an Ambiently Dried Aerogel Insulation (ADAI) that eliminates the need for expensive supercritical drying. It is believed that this report represents the first aerogel insulation that can be dried without undergoing a large volume change before "springing back" to near its original volume, which allows it to be cast into place into complex geometries and around rigid inclusions. This reduces a large barrier to the commercial viability of aerogel insulation. The advantages of

  17. High-Efficiency, Low-Temperature Regenerators for Cryocoolers Project (United States)

    National Aeronautics and Space Administration — Future NASA planetary and astrophysics missions will require various enhancements in multi-stage cryocoolers. These include increased efficiency, reduced vibration...

  18. Quantum Dot Spectrum Converters for Enhanced High Efficiency Photovoltaics Project (United States)

    National Aeronautics and Space Administration — This research proposes to enhance solar cell efficiency, radiation resistance and affordability. The Quantum Dot Spectrum Converter (QDSC) disperses quantum dots...

  19. Development of manufacturing capability for high-concentration, high-efficiency silicon solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Sinton, R.A.; Verlinden, P.J.; Crane, R.A.; Swanson, R.N. [SunPower Corp., Sunnyvale, CA (United States)


    This report presents a summary of the major results from a program to develop a manufacturable, high-efficiency silicon concentrator solar cell and a cost-effective manufacturing facility. The program was jointly funded by the Electric Power Research Institute, Sandia National Laboratories through the Concentrator Initiative, and SunPower Corporation. The key achievements of the program include the demonstration of 26%-efficient silicon concentrator solar cells with design-point (20 W/cm{sup 2}) efficiencies over 25%. High-performance front-surface passivations; that were developed to achieve this result were verified to be absolutely stable against degradation by 475 days of field exposure at twice the design concentration. SunPower demonstrated pilot production of more than 1500 of these cells. This cell technology was also applied to pilot production to supply 7000 17.7-cm{sup 2} one-sun cells (3500 yielded wafers) that demonstrated exceptional quality control. The average efficiency of 21.3% for these cells approaches the peak efficiency ever demonstrated for a single small laboratory cell within 2% (absolute). Extensive cost models were developed through this program and calibrated by the pilot-production project. The production levels achieved indicate that SunPower could produce 7-10 MW of concentrator cells per year in the current facility based upon the cell performance demonstrated during the program.


    Energy Technology Data Exchange (ETDEWEB)

    Dr. Paul T. Fini; Prof. Shuji Nakamura


    In this semiannual report we summarize the progress obtained in the first six months with the support of DoE contract No.DE-FC26-01NT41203, entitled ''High-Efficiency Nitride-Based Solid-State Lighting''. The two teams, from the University of California at Santa Barbara (Principle Investigator: Dr. Shuji Nakamura) and Rensselaer Polytechnic Institute (led by Dr. N. Narendran), are pursuing the goals of this contract from thin film growth, characterization, and packaging standpoints. The UCSB team has made significant progress in the development of GaN vertical cavity surface-emitting lasers (VCSELs) as well as light-emitting diodes (LEDs) with AlGaN active regions emitting in the ultraviolet (UV). The Rensselaer team has developed target specifications for some of the key parameters for the proposed solid-state lighting system, including a luminous flux requirement matrix for various lighting applications, optimal spectral power distributions, and the performance characteristics of currently available commercial LEDs for eventual comparisons to the devices developed in the scope of this project.


    Energy Technology Data Exchange (ETDEWEB)

    Dr. Paul T. Fini; Prof. Shuji Nakamura


    In this annual report we summarize the progress obtained in the first year with the support of DoE contract No.DE-FC26-01NT41203, entitled ''High-Efficiency Nitride-Based Solid-State Lighting''. The two teams, from the University of California at Santa Barbara (Principle Investigator: Dr. Shuji Nakamura) and Rensselaer Polytechnic Institute (led by Dr. N. Narendran), are pursuing the goals of this contract from thin film growth, characterization, and packaging standpoints. The UCSB team has made significant progress in the development of GaN vertical cavity surface-emitting lasers (VCSELs) as well as light-emitting diodes (LEDs) with AlGaN active regions emitting in the ultraviolet (UV). The Rensselaer team has developed target specifications for some of the key parameters for the proposed solid-state lighting system, including a luminous flux requirement matrix for various lighting applications, optimal spectral power distributions, and the performance characteristics of currently available commercial LEDs for eventual comparisons to the devices developed in the scope of this project.

  2. Improper ferroelectrics as high-efficiency energy conversion materials

    Energy Technology Data Exchange (ETDEWEB)

    Wakamatsu, Toru; Tanabe, Kenji; Terasaki, Ichiro; Taniguchi, Hiroki [Department of Physics, Nagoya University, Nagoya 464-8602 (Japan)


    An improper ferroelectric is a certain type of ferroelectrics whose primary order parameter is not polarization but another physical quantity such as magnetization. In contrast to a conventional proper ferroelectrics as represented by Pb(Zr,Ti)O{sub 3} and BaTiO{sub 3}, the improper ferroelectrics has been inconceivable for practical applications thus far. Herein, we illustrate the great potential of improper ferroelectrics for efficient conversion of temperature fluctuation to electric energy, as demonstrated with (Ca{sub 0.84}Sr{sub 0.16}){sub 8}[AlO{sub 2}]{sub 12}(MoO{sub 4}){sub 2} (CSAM-16). The present study has experimentally proven that CSAM-16 achieves an excellent electrothermal coupling factor and high electric field sensitivity for pyroelectric energy conversion that approach a practical level for application to self-powered autonomous electronic devices for rapidly spreading wireless sensor networks. The present results provide a novel approach to developing innovative pyroelectric energy harvesting devices using improper ferroelectrics. (copyright 2017 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  3. Energy Efficient High-Pressure Turbine Leakage Technology Report (United States)

    Gardner, W. B.


    The leakage test program was one of such supporting technology programs structured to provide guidance to the Energy Efficient Engine High Pressure Turbine Component Design Effort. Leakage reduction techniques were identified and evaluated. Test models were used to simulate component leak paths and to evaluate leakage reduction techniques. These models simulated the blade/disk attachment, the vane inner platform attachment, and the vane outer platform attachment combined with the blade outer airseal. Disk blade attachment testing indicated that leakage in this area could be reduced to very low levels by paying careful attention to the tolerances along the contact surface between the blade vibration damper and the blade platform contact surface. The aim of feather seal testing was to achieve a goal for an effective leakage gap of one mil (.001 inch) per inch of feather seal length. Results indicated that effective gaps even below the goal level were achievable by (1) maintaining close tolerances between feather seals and their slots to minimize end gaps and limit seal rotation, (2) avoiding feather seal overlap, and (3) minimizing feather seal intersections. W seals were shown to be effective leakage control devices. Wire rope, in its present state of development, was shown not to be an effective sealing concept for application to the component design.

  4. Dissolution-recrystallization method for high efficiency perovskite solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Han, Fei; Luo, Junsheng; Wan, Zhongquan; Liu, Xingzhao; Jia, Chunyang, E-mail:


    Highlights: • Dissolution-recrystallization method can improve perovskite crystallization. • Dissolution-recrystallization method can improve TiO{sub 2}/perovskite interface. • The optimal perovskite solar cell obtains the champion PCE of 16.76%. • The optimal devices are of high reproducibility. - Abstract: In this work, a dissolution-recrystallization method (DRM) with chlorobenzene and dimethylsulfoxide treating the perovskite films during the spin-coating process is reported. This is the first time that DRM is used to control perovskite crystallization and improve the device performance. Furthermore, the DRM is good for reducing defects and grain boundaries, improving perovskite crystallization and even improving TiO{sub 2}/perovskite interface. By optimizing, the DRM2-treated perovskite solar cell (PSC) obtains the best photoelectric conversion efficiency (PCE) of 16.76% under AM 1.5 G illumination (100 mW cm{sup −2}) with enhanced J{sub sc} and V{sub oc} compared to CB-treated PSC.

  5. High-Efficient Parallel CAVLC Encoders on Heterogeneous Multicore Architectures

    Directory of Open Access Journals (Sweden)

    H. Y. Su


    Full Text Available This article presents two high-efficient parallel realizations of the context-based adaptive variable length coding (CAVLC based on heterogeneous multicore processors. By optimizing the architecture of the CAVLC encoder, three kinds of dependences are eliminated or weaken, including the context-based data dependence, the memory accessing dependence and the control dependence. The CAVLC pipeline is divided into three stages: two scans, coding, and lag packing, and be implemented on two typical heterogeneous multicore architectures. One is a block-based SIMD parallel CAVLC encoder on multicore stream processor STORM. The other is a component-oriented SIMT parallel encoder on massively parallel architecture GPU. Both of them exploited rich data-level parallelism. Experiments results show that compared with the CPU version, more than 70 times of speedup can be obtained for STORM and over 50 times for GPU. The implementation of encoder on STORM can make a real-time processing for 1080p @30fps and GPU-based version can satisfy the requirements for 720p real-time encoding. The throughput of the presented CAVLC encoders is more than 10 times higher than that of published software encoders on DSP and multicore platforms.

  6. Highly efficient uptake of phosphorus in epiphytic bromeliads. (United States)

    Winkler, Uwe; Zotz, Gerhard


    Vascular epiphytes which can be abundant in tree crowns of tropical forests have to cope with low and highly intermittent water and nutrient supply from rainwater, throughfall and stem flow. Phosphorus rather than nitrogen has been suggested as the most limiting nutrient element, but, unlike nitrogen, this element has received little attention in physiological studies. This motivated the present report, in which phosphate uptake kinetics by leaves and roots, the subsequent distribution within plants and the metabolic fate of phosphate were studied as a step towards an improved understanding of physiological adaptations to the conditions of tree canopies. Radioactively labelled [(32)P]phosphate was used to study uptake kinetics and plant distribution of phosphorus absorbed from bromeliad tanks. The metabolism of low molecular phosphorus metabolites was analysed by thin-layer chromatography followed by autoradiography. Uptake of phosphate from tanks is an ATP-dependent process. The kinetics of phosphorus uptake suggest that epiphytes possess effective phosphate transporters. The K(m) value of 1.05 microm determined for leaves of the bromeliad Aechmea fasciata is comparable with values obtained for the high affinity phosphate transporters in roots of terrestrial plants. In this species, young leaves are the main sink for phosphate absorbed from tank water. Within these leaves, phosphate is then allocated from the basal uptake zone into distal sections of the leaves. More than 80 % of the phosphate incorporated into leaves is not used in metabolism but stored as phytin. Tank epiphytes are adapted to low and intermittent nutrient supply by different mechanisms. They possess an effective mechanism to take up phosphate, minimizing dilution and loss of phosphorus captured in the tank. Available phosphorus is taken up from the tank solution almost quantitatively, and the surplus not needed for current metabolism is accumulated in reserves, i.e. plants show luxury

  7. High Photovoltaic Quantum Efficiency in Ultrathin van der Waals Heterostructures. (United States)

    Wong, Joeson; Jariwala, Deep; Tagliabue, Giulia; Tat, Kevin; Davoyan, Artur R; Sherrott, Michelle C; Atwater, Harry A


    We report experimental measurements for ultrathin (van der Waals heterostructures exhibiting external quantum efficiencies exceeding 50% and show that these structures can achieve experimental absorbance >90%. By coupling electromagnetic simulations and experimental measurements, we show that pn WSe 2 /MoS 2 heterojunctions with vertical carrier collection can have internal photocarrier collection efficiencies exceeding 70%.

  8. Analysis and design of a high-efficiency zero-voltage-switching step ...

    Indian Academy of Sciences (India)

    switching; zero-current-switching. 1. Introduction. Recently, high-efficiency power conversion techniques have been researched due to the increas- ing emphasis on the environment protection and energy saving. Also, high efficiency is one of.

  9. Impact of high efficiency vehicles on future fuel tax revenues in Utah. (United States)


    The Utah Department of Transportation Research Division has analyzed the potential impact of : high-efficiency motor vehicles on future State of Utah motor fuel tax revenues used to construct and maintain the : highway network. High-efficiency motor ...

  10. Advanced Nanomaterials for High-Efficiency Solar Cells

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Junhong [University of Wisconsin-Milwaukee


    Energy supply has arguably become one of the most important problems facing humankind. The exponential demand for energy is evidenced by dwindling fossil fuel supplies and record-high oil and gas prices due to global population growth and economic development. This energy shortage has significant implications to the future of our society, in addition to the greenhouse gas emission burden due to consumption of fossil fuels. Solar energy seems to be the most viable choice to meet our clean energy demand given its large scale and clean/renewable nature. However, existing methods to convert sun light into electricity are not efficient enough to become a practical alternative to fossil fuels. This DOE project aims to develop advanced hybrid nanomaterials consisting of semiconductor nanoparticles (quantum dots or QDs) supported on graphene for cost-effective solar cells with improved conversion efficiency for harvesting abundant, renewable, clean solar energy to relieve our global energy challenge. Expected outcomes of the project include new methods for low-cost manufacturing of hybrid nanostructures, systematic understanding of their properties that can be tailored for desired applications, and novel photovoltaic cells. Through this project, we have successfully synthesized a number of novel nanomaterials, including vertically-oriented graphene (VG) sheets, three-dimensional (3D) carbon nanostructures comprising few-layer graphene (FLG) sheets inherently connected with CNTs through sp{sup 2} carbons, crumpled graphene (CG)-nanocrystal hybrids, CdSe nanoparticles (NPs), CdS NPs, nanohybrids of metal nitride decorated on nitrogen-doped graphene (NG), QD-carbon nanotube (CNT) and QD-VG-CNT structures, TiO{sub 2}-CdS NPs, and reduced graphene oxide (RGO)-SnO{sub 2} NPs. We further assembled CdSe NPs onto graphene sheets and investigated physical and electronic interactions between CdSe NPs and the graphene. Finally we have demonstrated various applications of these

  11. A High-Efficiency and High-Resolution Straw Tube Tracker for the LHCb Experiment

    CERN Document Server

    Tuning, Niels


    The Outer Tracker detector for the LHCb experiment at CERN will provide accurate position information on the charged particles in B-decays. It is crucial to accurately and efficiently detect these particles, in the high-density particle environment of the LHC. For this, the Outer Tracker is being constructed, consisting of $\\sim$ 55,000 straw tubes, covering in total an area of 360 m$^2$ of double layers. At present, approximately 90% of the detector has been constructed and fully tested. In addition, a beam test has been performed at DESY, Hamburg, to validate the final read-out electronics, in terms of efficiency, position resolution, noise and cross talk.


    Energy Technology Data Exchange (ETDEWEB)

    Kolarik, Robert V. II; Shattuck, Charles W.; Copper, Anthony P.


    This Low Friction (High Efficiency Roller Bearing) Engine (LFE) report presents the work done by The Timken Company to conduct a technology demonstration of the benefits of replacing hydrodynamic bearings with roller bearings in the crankshaft and camshaft assemblies of an internal combustion engine for the purpose of collecting data sufficient to prove merit. The engines in the present study have been more extensively converted to roller bearings than any previous studies (40 needle roller bearings per engine) to gain understanding of the full potential of application of bearing technology. The project plan called for comparative testing of a production vehicle which was already respected for having demonstrated low engine friction levels with a rollerized version of that engine. Testing was to include industry standard tests for friction, emissions and fuel efficiency conducted on instrumented dynamometers. Additional tests for fuel efficiency, cold start resistance and other measures of performance were to be made in the actual vehicle. Comparative measurements of noise, vibration and harshness (NVH), were planned, although any work to mitigate the suspected higher NVH level in the rollerized engine was beyond the scope of this project. Timken selected the Toyota Avalon with a 3.5L V-6 engine as the test vehicle. In an attempt to minimize cost and fabrication time, a ‘made-from’ approach was proposed in which as many parts as possible would be used or modified from production parts to create the rollerized engine. Timken commissioned its test partner, FEV Engine Technology, to do a feasibility study in which they confirmed that using such an approach was possible to meet the required dimensional restrictions and tolerances. In designing the roller bearing systems for the crank and cam trains, Timken utilized as many production engine parts as possible. The crankshafts were produced from production line forgings, which use Timken steel, modified with special

  13. Performance Testing of a Lightweight, High Efficiency 95 K Cryocooler (United States)

    Salerno, Lou; Kittel, P.; Kashani, A.; Helvensteijn, B. P. M.; Tward, E.; Arnold, Jim A. (Technical Monitor)


    Performance data are presented for a flight-like, lightweight, high efficiency pulse tube cryogenic cooler. The cooler has a mass of less than 4.0 kg, and an efficiency of 12 W/W, which is 18% of Carnot at 95 K, nearly double the efficiency of previous cooler designs, The mass of the cooler has been reduced by approximately a factor of three. The design point cooling power is 10 watts at 95 K at a heat rejection temperature of 300 K. The no-load temperature is 45 K. The compressor is built by Hymatic Engineering, UK, and is of a horizontally opposed piston design using flexure bearings. The vertical pulse tube is built by TRW with the heat exchanger or cold block located approximately mid-way along the tube. The final assembly and integration is also performed by TRW. The inertance tube and dead volume are contained within one of the compressor end caps. The cooler was developed by TRW under a joint NASA-DOD program, and has a goal of 10 yr operating lifetime. Potential NASA applications will focus on using coolers of this type in Zero boil off (ZBO) cryogen storage topologies for next generation launch vehicles. Zero boil off systems will feature significant reductions in tank size and Initial Mass to Low Earth Orbit (IMLEO), thereby significantly reducing the cost of access to space, and enabling future missions. The coolers can be used directly in liquid oxygen (LOx) or liquid methane ZBO systems, as shield coolers in liquid hydrogen tanks, or as first stage coolers in two-stage liquid hydrogen (LH2) ZBO cooler systems. Finally, the coolers could find applications in exploration missions where either propellants or breathable oxygen are extracted from the planetary atmosphere using a Sabatier or similar process. The gases could then be liquefied for storage either directly in return vehicle propellant tanks or on the planetary surface. Data presented were taken with the cooler operating in a vacuum of 10 (exp -5) torr, at controlled rejection temperatures from

  14. Development of a photomultiplier tube with high quantum efficiency

    CERN Document Server

    Shima, T


    We propose a new method to significantly increase the quantum efficiency of a photomultiplier tube by employing a multi-photocathode and a mirror to produce photoelectrons by reusing photons transmitted by a single photocathode. In order to estimate the expected performance of the new photomultiplier, we studied the spectral responses of the reflectance, transmittance, and quantum efficiency of a K sub 2 CsSb photocathode as a function of the wavelength of incident light. A large enhancement of the quantum efficiency is expected in the regions between lambda=280 and 650 nm. (author)

  15. Exciplex-Forming Cohost for High Efficiency and High Stability Phosphorescent Organic Light-Emitting Diodes. (United States)

    Shih, Chun-Jen; Lee, Chih-Chien; Chen, Ying-Hao; Biring, Sajal; Kumar, Gautham; Yeh, Tzu-Hung; Sen, Somaditya; Liu, Shun-Wei; Wong, Ken-Tsung


    An exciplex forming cohost system is employed to achieve a highly efficient organic light-emitting diode (OLED) with good electroluminescent lifetime. The exciplex is formed at the interfacial contact of a conventional star-shaped carbazole hole-transporting material, 4,4',4″-tris(N-carbazolyl)-triphenylamine (TCTA), and a triazine electron-transporting material, 2,4,6-tris[3-(1H-pyrazol-1-yl)phenyl]-1,3,5-triazine (3P-T2T). The excellent combination of TCTA and 3P-T2T is applied as the cohost of a common green phosphorescent emitter with almost zero energy loss. When Ir(ppy)2(acac) is dispersed in such exciplex cohost system, OLED device with maximum external quantum efficiency of 29.6%, the ultrahigh power efficiency of 147.3 lm/W, and current efficiency of 107 cd/A were successfully achieved. More importantly, the OLED device showed a low-efficiency roll-off and an operational lifetime (τ80) of ∼1020 min with the initial brightness of 2000 cd/m2, which is 56 times longer than the reference device. The significant difference of device stability was attributed to the degradation of exciplex system for energy transfer process, which was investigated by the photoluminescence aging measurement at room temperature and 100 K, respectively.

  16. Highly efficient DNA extraction method from skeletal remains

    Directory of Open Access Journals (Sweden)

    Irena Zupanič Pajnič


    Full Text Available Background: This paper precisely describes the method of DNA extraction developed to acquire high quality DNA from the Second World War skeletal remains. The same method is also used for molecular genetic identification of unknown decomposed bodies in routine forensic casework where only bones and teeth are suitable for DNA typing. We analysed 109 bones and two teeth from WWII mass graves in Slovenia. Methods: We cleaned the bones and teeth, removed surface contaminants and ground the bones into powder, using liquid nitrogen . Prior to isolating the DNA in parallel using the BioRobot EZ1 (Qiagen, the powder was decalcified for three days. The nuclear DNA of the samples were quantified by real-time PCR method. We acquired autosomal genetic profiles and Y-chromosome haplotypes of the bones and teeth with PCR amplification of microsatellites, and mtDNA haplotypes 99. For the purpose of traceability in the event of contamination, we prepared elimination data bases including genetic profiles of the nuclear and mtDNA of all persons who have been in touch with the skeletal remains in any way. Results: We extracted up to 55 ng DNA/g of the teeth, up to 100 ng DNA/g of the femurs, up to 30 ng DNA/g of the tibias and up to 0.5 ng DNA/g of the humerus. The typing of autosomal and YSTR loci was successful in all of the teeth, in 98 % dekalof the femurs, and in 75 % to 81 % of the tibias and humerus. The typing of mtDNA was successful in all of the teeth, and in 96 % to 98 % of the bones. Conclusions: We managed to obtain nuclear DNA for successful STR typing from skeletal remains that were over 60 years old . The method of DNA extraction described here has proved to be highly efficient. We obtained 0.8 to 100 ng DNA/g of teeth or bones and complete genetic profiles of autosomal DNA, Y-STR haplotypes, and mtDNA haplotypes from only 0.5g bone and teeth samples.

  17. Thermophotonics for ultra-high efficiency visible LEDs (United States)

    Ram, Rajeev J.


    The wall-plug efficiency of modern light-emitting diodes (LEDs) has far surpassed all other forms of lighting and is expected to improve further as the lifetime cost of a luminaire is today dominated by the cost of energy. The drive towards higher efficiency inevitably opens the question about the limits of future enhancement. Here, we investigate thermoelectric pumping as a means for improving efficiency in wide-bandgap GaN based LEDs. A forward biased diode can work as a heat pump, which pumps lattice heat into the electrons injected into the active region via the Peltier effect. We experimentally demonstrate a thermally enhanced 450 nm GaN LED, in which nearly fourfold light output power is achieved at 615 K (compared to 295 K room temperature operation), with virtually no reduction in the wall-plug efficiency at bias V efficiency GaN LEDs suggests that Peltier thermal pumping plays a more important role in a wide range of modern LED structures that previously thought - opening a path to even higher efficiencies and lower lifetime costs for future lighting.

  18. High-Efficiency Polycrystalline Thin Film Tandem Solar Cells. (United States)

    Kranz, Lukas; Abate, Antonio; Feurer, Thomas; Fu, Fan; Avancini, Enrico; Löckinger, Johannes; Reinhard, Patrick; Zakeeruddin, Shaik M; Grätzel, Michael; Buecheler, Stephan; Tiwari, Ayodhya N


    A promising way to enhance the efficiency of CIGS solar cells is by combining them with perovskite solar cells in tandem devices. However, so far, such tandem devices had limited efficiency due to challenges in developing NIR-transparent perovskite top cells, which allow photons with energy below the perovskite band gap to be transmitted to the bottom cell. Here, a process for the fabrication of NIR-transparent perovskite solar cells is presented, which enables power conversion efficiencies up to 12.1% combined with an average sub-band gap transmission of 71% for photons with wavelength between 800 and 1000 nm. The combination of a NIR-transparent perovskite top cell with a CIGS bottom cell enabled a tandem device with 19.5% efficiency, which is the highest reported efficiency for a polycrystalline thin film tandem solar cell. Future developments of perovskite/CIGS tandem devices are discussed and prospects for devices with efficiency toward and above 27% are given.

  19. Achieving high performance polymer optoelectronic devices for high efficiency, long lifetime and low fabrication cost (United States)

    Huang, Jinsong

    This thesis described three types of organic optoelectronic devices: polymer light emitting diodes (PLED), polymer photovoltaic solar cell, and organic photo detector. The research in this work focuses improving their performance including device efficiency, operation lifetime simplifying fabrication process. With further understanding in PLED device physics, we come up new device operation model and improved device architecture design. This new method is closely related to understanding of the science and physics at organic/metal oxide and metal oxide/metal interface. In our new device design, both material and interface are considered in order to confine and balance all injected carriers, which has been demonstrated very be successful in increasing device efficiency. We created two world records in device efficiency: 18 lm/W for white emission fluorescence PLED, 22 lm/W for red emission phosphorescence PLED. Slow solvent drying process has been demonstrated to significantly increase device efficiency in poly(3-hexylthiophene) (P3HT) and [6,6]-phenyl C 61-butyric acid methyl ester (PCBM) mixture polymer solar cell. From the mobility study by time of flight, the increase of efficiency can be well correlated to the improved carrier transport property due to P3HT crystallization during slow solvent drying. And it is found that, similar to PLED, balanced carrier mobility is essential in high efficient polymer solar cell. There is also a revolution in our device fabrication method. A unique device fabrication method is presented by an electronic glue based lamination process combined with interface modification as a one-step polymer solar cell fabrication process. It can completely skip the thermal evaporation process, and benefit device lifetime by several merits: no air reactive. The device obtained is metal free, semi-transparent, flexible, self-encapsulated, and comparable efficiency with that by regular method. We found the photomultiplication (PM) phenomenon in C

  20. High-speed, FPGA-based photon-counting fluorometer with high data-gathering efficiency (United States)

    Iwata, Tetsuo; Mizuno, Takahiko


    We have developed a low-cost, high-efficiency fluorometer using a field-programmable gate array and simultaneous detection of photoelectron pulse trains. The fluorometer covers a time span of 64 ns with a resolution of 1.0 ns/channel. Depending on the number of channels, the signal-gathering efficiency was improved by a factor of 100 relative to that of conventional time-correlated single-photon counting. This assumes that the fluorescence intensity is moderately high but still requires photon counting. The dead time for building a histogram has been reduced to zero, which means that the upper limit of the repetitive excitation frequency could exceed that determined by the time span. We describe instrumental details and demonstrate the basic performance.

  1. A versatile, highly-efficient, high-resolution von Hamos Bragg crystal x-ray spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Vane, C.R.; Smith, M.S.; Raman, S.


    An efficient, high-resolution, vertical-focusing, Bragg crystal x-ray spectrometer has been specifically designed and constructed for use in measurements of x rays produced in collisions of energetic heavy ions. In this report the design and resulting operational characteristics of the final instrument are fully described. A wide variety of sample data is also included to illustrate the utility of this device in several areas of research. 14 refs., 38 figs.

  2. The impact of monthly variation of the Pacific–North America (PNA teleconnection pattern on wintertime surface-layer aerosol concentrations in the United States

    Directory of Open Access Journals (Sweden)

    J. Feng


    Full Text Available The Pacific–North America teleconnection (PNA is the leading general circulation pattern in the troposphere over the region of North Pacific to North America during wintertime. This study examined the impacts of monthly variations of the PNA phase (positive or negative phase on wintertime surface-layer aerosol concentrations in the United States (US by analyzing observations during 1999–2013 from the Air Quality System of the Environmental Protection Agency (EPA-AQS and the model results for 1986–2006 from the global three-dimensional Goddard Earth Observing System (GEOS chemical transport model (GEOS-Chem. The composite analyses on the EPA-AQS observations over 1999–2013 showed that the average concentrations of PM2.5, sulfate, nitrate, ammonium, organic carbon, and black carbon aerosols over the US were higher in the PNA positive phases (25 % of the winter months examined, and this fraction of months had the highest positive PNA index values than in the PNA negative phases (25 % of the winter months examined, and this fraction of months had the highest negative PNA index values by 1.0 µg m−3 (8.7 %, 0.01 µg m−3 (0.5 %, 0.3 µg m−3 (29.1 %, 0.1 µg m−3 (11.9 %, 0.6 µg m−3 (13.5 %, and 0.2 µg m−3 (27.8 %, respectively. The simulated geographical patterns of the differences in concentrations of all aerosol species between the PNA positive and negative phases were similar to observations. Based on the GEOS-Chem simulation, the pattern correlation coefficients were calculated to show the impacts of PNA-induced variations in meteorological fields on aerosol concentrations. The PNA phase was found (i to influence sulfate concentrations mainly through changes in planetary boundary layer height (PBLH, precipitation (PR, and temperature; (ii to influence nitrate concentrations mainly through changes in temperature; and (iii to influence concentrations of ammonium, organic carbon, and black

  3. Development of high-efficiency solar cells on silicon web (United States)

    Meier, D. L.


    Achievement of higher efficiency cells by directing efforts toward identifying carrier loss mechanisms; design of cell structures; and development of processing techniques are described. Use of techniques such as deep-level transient spectroscopy (DLTS), laser-beam-induced current (LBIC), and transmission electron microscopy (TEM) indicated that dislocations in web material rather than twin planes were primarily responsible for limiting diffusion lengths in the web. Lifetimes and cell efficiencies can be improved from 19 to 120 microns, and 8 to 10.3% (no AR), respectively, by implanting hydrogen at 1500 eV and a beam current density of 2.0 mA/sq cm. Some of the processing improvements included use of a double-layer AR coating (ZnS and MgF2) and an addition of an aluminum back surface reflectors. Cells of more than 16% efficiency were achieved.

  4. High efficiency and stable white OLED using a single emitter

    Energy Technology Data Exchange (ETDEWEB)

    Li, Jian [Arizona State Univ., Tempe, AZ (United States). School of Mechanical, Aerospace, Chemical and Materials Engineering


    The ultimate objective of this project was to demonstrate an efficient and stable white OLED using a single emitter on a planar glass substrate. The focus of the project is on the development of efficient and stable square planar phosphorescent emitters and evaluation of such class of materials in the device settings. Key challenges included improving the emission efficiency of molecular dopants and excimers, controlling emission color of emitters and their excimers, and improving optical and electrical stability of emissive dopants. At the end of this research program, the PI has made enough progress to demonstrate the potential of excimer-based white OLED as a cost-effective solution for WOLED panel in the solid state lighting applications.

  5. High-Efficiency, Commercial Ready CdTe Solar Cells

    Energy Technology Data Exchange (ETDEWEB)

    Sites, James R. [Colorado State Univ., Fort Collins, CO (United States)


    Colorado State’s F-PACE project explored several ways to increase the efficiency of CdTe solar cells and to better understand the device physics of those cells under study. Increases in voltage, current, and fill factor resulted in efficiencies above 17%. The three project tasks and additional studies are described in detail in the final report. Most cells studied were fabricated at Colorado State using an industry-compatible single-vacuum closed-space-sublimation (CSS) chamber for deposition of the key semiconductor layers. Additionally, some cells were supplied by First Solar for comparison purposes, and a small number of modules were supplied by Abound Solar.

  6. Nano-patterned superconducting surface for high quantum efficiency cathode (United States)

    Hannon, Fay; Musumeci, Pietro


    A method for providing a superconducting surface on a laser-driven niobium cathode in order to increase the effective quantum efficiency. The enhanced surface increases the effective quantum efficiency by improving the laser absorption of the surface and enhancing the local electric field. The surface preparation method makes feasible the construction of superconducting radio frequency injectors with niobium as the photocathode. An array of nano-structures are provided on a flat surface of niobium. The nano-structures are dimensionally tailored to interact with a laser of specific wavelength to thereby increase the electron yield of the surface.

  7. Ultra-high cell-density silicon photomultipliers with high detection efficiency (United States)

    Acerbi, Fabio; Gola, Alberto; Regazzoni, Veronica; Paternoster, Giovanni; Borghi, Giacomo; Piemonte, Claudio; Zorzi, Nicola


    Silicon photomultipliers (SiPMs) are arrays of many single-photon avalanche diodes (SPADs), all connected in parallel. Each SPAD is sensitive to single photons and the SiPM gives an output proportional to the number of detected photons. These sensors are becoming more and more popular in different applications, from high-energy physics to spectroscopy, and they have been significantly improved over last years, decreasing the noise, increasing the cell fill-factor (FF) and thus achieving very high photon-detection efficiency (PDE). In FBK (Trento, Italy), we developed new SiPM technologies with high-density (HD) and, more recently, ultra-high-density (UHD) of cells (i.e. density of SPADs). These technologies employ deep-trenches between cells, for electrical and optical isolation. As an extreme case the smallest-cell, SiPM, i.e. with 5μm cell pitch, has about 40000 SPADs per squared millimeter. Such small SPAD dimensions gives a significantly high dynamic range to the SiPM. These small-cells SiPM have a lower correlated noise (including lower afterpulsing probability) and a faster recharge time (in the order of few nanoseconds), and they also preserve a very good detection efficiency (despite the small SPAD dimension).

  8. High efficiency energy conversion from liquid jet flow

    NARCIS (Netherlands)

    Xie, Yanbo; de Vreede, Lennart; Nguyen, Trieu; de Boer, Hans L.; Sprenkels, A.J.; van den Berg, Albert; Eijkel, Jan C.T.; Fujii, T.; Hibara, A.; Takeuchi, S.; Fukuba, T.


    We investigate the performance of a microfluidic energy conversion system using jetting flow. Preliminary results indicate that a voltage can be generated of several kilo-Volts and energy efficiencies can reach 15%. Such values are by far the highest obtained for electrokinetic conversion systems


    African Journals Online (AJOL)


    tert-butyl dicarbonate (Boc2O). This was followed by the esterification and deprotection of compound 3 at an overall yield of 82%. The mixture of thionyl chloride and methanol was found as an efficient reagent for simultaneous deprotection of tert-butoxycarbonyl (Boc) group and esterification of carboxy group of compound.

  10. An Automatic High Efficient Method for Dish Concentrator Alignment

    Directory of Open Access Journals (Sweden)

    Yong Wang


    for the alignment of faceted solar dish concentrator. The isosceles triangle configuration of facet’s footholds determines a fixed relation between light spot displacements and foothold movements, which allows an automatic determination of the amount of adjustments. Tests on a 25 kW Stirling Energy System dish concentrator verify the feasibility, accuracy, and efficiency of our method.

  11. Development of high efficiency solar cells on silicon web (United States)

    Rohatgi, A.; Meier, D. L.; Campbell, R. B.; Schmidt, D. N.; Rai-Choudhury, P.


    Web base material is being improved with a goal toward obtaining solar cell efficiencies in excess of 18% (AM1). Carrier loss mechanisms in web silicon was investigated, techniques were developed to reduce carrier recombination in the web, and web cells were fabricated using effective surface passivation. The effect of stress on web cell performance was also investigated.

  12. Gate controlled high efficiency ballistic energy conversion system

    NARCIS (Netherlands)

    Xie, Yanbo; Bos, Diederik; de Boer, Hans L.; van den Berg, Albert; Eijkel, Jan C.T.; Zengerle, R.


    Last year we demonstrated the microjet ballistic energy conversion system[1]. Here we show that the efficiency of such a system can be further improved by gate control. With gate control the electrical current generation is enhanced a hundred times with respect to the current generated from the zeta

  13. Energy conversion approaches and materials for high-efficiency photovoltaics (United States)

    Green, Martin A.; Bremner, Stephen P.


    The past five years have seen significant cost reductions in photovoltaics and a correspondingly strong increase in uptake, with photovoltaics now positioned to provide one of the lowest-cost options for future electricity generation. What is becoming clear as the industry develops is that area-related costs, such as costs of encapsulation and field-installation, are increasingly important components of the total costs of photovoltaic electricity generation, with this trend expected to continue. Improved energy-conversion efficiency directly reduces such costs, with increased manufacturing volume likely to drive down the additional costs associated with implementing higher efficiencies. This suggests the industry will evolve beyond the standard single-junction solar cells that currently dominate commercial production, where energy-conversion efficiencies are fundamentally constrained by Shockley-Queisser limits to practical values below 30%. This Review assesses the overall prospects for a range of approaches that can potentially exceed these limits, based on ultimate efficiency prospects, material requirements and developmental outlook.

  14. Highly efficient catalytic reductive degradation of various organic ...

    Indian Academy of Sciences (India)

    CeO₂-TiO₂ nano-hybrid along with NaBH₄ exhibited remarkable catalytic activities towards all the probed dyes, namely Methylene Blue, Methyl Orange, Congo Red, Rhodamine B and Malachite Green, with a degradation efficiency of ~100% in ...

  15. High-efficiency regeneration of peanut (Arachis hypogaea L.) plants ...

    African Journals Online (AJOL)



    Oct 3, 2011 ... Somatic embryogenesis from the axillary meristems of peanut (Arachis hypogaea L.). Plant Biotechnol. Rep. 3(4): 333-340. Srinivasan T, Kumar K, Kirti P (2010). Establishment of efficient and rapid regeneration system for some diploid wild species of Arachis. Plant Cell Tissue Org. Cult. 101(3): 303-309.

  16. Low-Cost, High Efficiency, Silicon Based Photovoltaic Devices (United States)


    C. Thicker interface layers impose higher barrier potentials for charge carriers to tunnel through, hindering the collection efficiency of the...93 Silicon nanowires fabrication on ultrathin silicon membranes...Calculated reflectivity of (a) single layer silicon nitride (Si3N4) antireflection coating for normal incidence for different layer thickness, (b

  17. High efficiency input-output prism waveguide coupler: an analysis. (United States)

    Sarid, D


    The theory and experimental results of the performance of a practical prism waveguide input-output coupler are presented. The coupling scheme, which results in a 94% coupling efficiency, uses a single prism for both input and output coupling, with the light propagating 1 cm in the LiNbO(3) Ti in diffused waveguide.

  18. Highly efficient and stable catalyst for peroxynitrite decomposition (United States)

    Yurii V. Geletii; Alan J. Bailey; Jennifer J. Cowan; Ira A. Weinstock; Craig L. Hill


    The new cobalt substituted-polyoxometalate K7[CoAlW11O39]•15H2O and the simple CoCl2•6H2O salt are efficient catalysts for peroxynitrite decomposition. These compounds also catalyze the oxidation of ascorbic acid and the nitration of phenol by peroxynitrite.

  19. Highly Efficient Production of Laccase by the Basidiomycete Pycnoporus cinnabarinus

    NARCIS (Netherlands)

    Alves, AMCR; Record, E; Lomascolo, A; Scholtmeijer, K; Asther, M; Wessels, JGH; Wosten, HAB


    An efficient transformation and expression system was developed for the industrially relevant basidiomycete Pycnoporus cinnabarinus. This was used to transform a laccase-deficient monokaryotic strain with the homologous lac1 laccase gene placed under the regulation of its own promoter or that of the

  20. Highly efficient 6-stroke engine cycle with water injection (United States)

    Szybist, James P; Conklin, James C


    A six-stroke engine cycle having improved efficiency. Heat is recovered from the engine combustion gases by using a 6-stroke engine cycle in which combustion gases are partially vented proximate the bottom-dead-center position of the fourth stroke cycle, and water is injected proximate the top-dead-center position of the fourth stroke cycle.

  1. 20 W High Efficiency 1550 nm Pulsed Fiber Laser Project (United States)

    National Aeronautics and Space Administration — High peak power short pulsed lasers have been considered to be an enabling technology to build high power transmitters for future deep space high rate space...

  2. High efficiency off-axis current drive by high frequency fast waves (United States)

    Prater, R.; Pinsker, R. I.; Moeller, C. P.; Porkolab, M.; Vdovin, V.


    Modeling work shows that current drive can be done off-axis with high efficiency, as required for FNSF and DEMO, by using very high harmonic fast waves ("helicons" or "whistlers"). The modeling indicates that plasmas with high electron beta are needed in order for the current drive to take place off-axis, making DIII-D a highly suitable test vehicle for this process. The calculations show that the driven current is not very sensitive to the launched value of n∥, a result that can be understood from examination of the evolution of n∥ as the waves propagate in the plasma. Because of this insensitivity, relatively large values (˜3) of n∥ can be launched, thereby avoiding some of the problems with mode conversion in the boundary found in some previous experiments. Use of a traveling wave antenna provides a very narrow n∥ spectrum, which also helps avoid mode conversion.

  3. High-Efficiency, High-Capacity, Low-NOx Aluminum Melting Using Oxygen-Enhanced Combustion

    Energy Technology Data Exchange (ETDEWEB)

    D' Agostini, M.D.


    This report describes the development and application of a novel oxygen enhanced combustion system with an integrated vacuum swing adsorption (VSA) oxygen supply providing efficient, low NOx melting in secondary aluminum furnaces. The mainstay of the combustion system is a novel air-oxy-natural gas burner that achieves high productivity and energy efficiency with low NOx emissions through advanced mixing concepts and the use of separate high- and low-purity oxidizer streams. The technology was installed on a reverberatory, secondary aluminum melting plant at the Wabash Aluminum Alloy's Syracuse, N.Y. plant, where it is currently in operation. Field testing gave evidence that the new burner technology meets the stringent NOx emissions target of 0.323 lb NO2/ton aluminum, thus complying with regulations promulgated by Southern California's South Coast Air Quality Management District (SCAQMD). Test results also indicated that the burner technology exceeded fuel efficiency and melting capacity goals. Economic modeling showed that the novel air-oxy-fuel (ADF) combustion technology provides a substantial increase in furnace profitability relative to air-fuel operation. Model results also suggest favorable economics for the air-oxy-fuel technology relative to a full oxy-fuel conversion of the furnace.

  4. Basic concepts for the design of high-efficiency single-junction and multibandgap solar cells (United States)

    Fan, J. C. C.


    Concepts for obtaining practical solar-cell modules with one-sun efficiencies up to 30 percent at air mass 1 are now well understood. Such high-efficiency modules utilize multibandgap structures. To achieve module efficiencies significantly above 30 percent, it is necessary to employ different concepts such as spectral compression and broad-band detection. A detailed description of concepts for the design of high-efficiency multibandgap solar cells is given.

  5. Highly efficient catalytic systems based on Pd-coated microbeads (United States)

    Lim, Jin Hyun; Cho, Ahyoung; Lee, Seung Hwan; Park, Bumkyo; Kang, Dong Woo; Koo, Chong Min; Yu, Taekyung; Park, Bum Jun


    The efficiency of two prototype catalysis systems using palladium (Pd)-coated microparticles was investigated with regard to the recovery and recyclability of the catalytic particles. One such system was the interface-adsorption method, in which polymer particles coated with Pd nanoparticles strongly and irreversibly attach to the oil-water interface. Due to the irreversible adsorption of the catalytic particles to the interface, particle loss was completely prevented while mixing the aqueous solution and while collecting the products. The other system was based on the magnetic field-associated particle recovery method. The use of polymeric microparticles containing Pd nanoparticles and magnetite nanoparticles accelerated the sedimentation of the particles in the aqueous phase by applying a strong magnetic field, consequently suppressing drainage of the particles from the reactor along the product stream. Upon multiple runs of the catalytic reactions, it was found that conversion does not change significantly, demonstrating the excellent recyclability and performance efficiency in the catalytic processes.

  6. High-efficiency large-area CdTe panels

    Energy Technology Data Exchange (ETDEWEB)

    Albright, S.P.; Chamberlin, R.R.; Jordan, J.F. (Photon Energy, Inc., El Paso, TX (USA))


    The objective of this three year effort has been to develop an improved materials technology and fabrication process for limited volume production of 1 ft{sup 2} and 4 ft{sup 2} CdS/CdTe photovoltaic modules. The module stability objective by the end of this three year subcontract was to develop techniques to provide ten year life exploration with no greater than 10% degradation. In order to achieve these efficiency and stability objectives, the research program has been separated into tasks including: (1) analysis and characterization of CdS/CdTe Devices; (2) performance optimization on small cells; (3) encapsulation and stability testing; and (4) module efficiency optimization. 27 refs., 18 figs., 3 tabs.

  7. Novel approach for the assembly of highly efficient SERS substrates. (United States)

    Cerf, Aline; Molnár, Gábor; Vieu, Christophe


    In this paper we present the properties of surface-enhanced Raman scattering (SERS) active substrates elaborated by a low-cost approach. Our methodology relying on capillary assembly and soft lithography allows us to generate periodic two-dimensional (2D) matrixes of 100 nm gold nanoparticle patterns in a very precise, cost-efficient, and large-scale manner. For this study, we assembled nanoparticle aggregates of different sizes (one to six particles) in order to determine the influence of the aggregation on the local electric field enhancement. We further demonstrate that this substrate is greatly efficient not only for SERS but also in metal-enhanced fluorescence (MEF) for local enhancement of conventional fluorescence.

  8. High-efficiency fused-silica reflection grism. (United States)

    Cao, Hongchao; Zhou, Changhe; Ma, Jianyong; Wu, Jun; Li, Shubin


    A fused-silica reflection grism (combination of grating and prism) based on the phenomenon of total internal reflection (TIR), and used in the -1st order, is designed and fabricated. The grism is etched directly into the fused-silica prism, which greatly facilitates the use of the TIR grating as no other angle coupling devices are involved. The grating profile is optimized by the use of the rigorous coupled-wave analysis method. Diffraction efficiency of larger than 99% at a wavelength of 980 nm for TM-polarized waves can be theoretically obtained. Two-beam interference lithography and inductively coupled plasma etching techniques are used to manufacture such grism. Diffraction efficiencies of larger than 95% are experimentally demonstrated.

  9. High flux zeolite membranes for efficient production of biofuels


    Sandström, Linda


    The greenhouse effect and the limited fossil oil resources have increased the demand for renewable fuels. Zeolite membranes have potential applications in numerous separation processes, and could be useful in the development of efficient processes for renewable fuel production.Synthesis gas is a gas mixture containing mainly carbon monoxide, hydrogen and carbon dioxide. Synthesis gas produced from biomass usually contains more carbon dioxide than desired, and it also contains hydrogen sulphid...

  10. A Highly Efficient Design Strategy for Regression with Outcome Pooling


    Mitchell, Emily M.; Lyles, Robert H.; Manatunga, Amita K.; Perkins, Neil J.; Schisterman, Enrique F.


    The potential for research involving biospecimens can be hindered by the prohibitive cost of performing laboratory assays on individual samples. To mitigate this cost, strategies such as randomly selecting a portion of specimens for analysis or randomly pooling specimens prior to performing laboratory assays may be employed. These techniques, while effective in reducing cost, are often accompanied by a considerable loss of statistical efficiency. We propose a novel pooling stra...

  11. Highly efficient perovskite solar cells with crosslinked PCBM interlayers

    KAUST Repository

    Qiu, W.


    Commercially available phenyl-C-butyric acid methyl ester (PCBM) is crosslinked with 1,6-diazidohexane (DAZH), resulting in films resistant to common solvents used in perovskite solar cell processing. By using crosslinked PCBM as an interlayer and (HC(NH))(CHNH)PbIBr as the active layer, we achieve small area devices and modules with a maximum steady-state power conversion efficiency of 18.1% and 14.9%, respectively.

  12. Small molecules enable highly efficient neuronal conversion of human fibroblasts. (United States)

    Ladewig, Julia; Mertens, Jerome; Kesavan, Jaideep; Doerr, Jonas; Poppe, Daniel; Glaue, Finnja; Herms, Stefan; Wernet, Peter; Kögler, Gesine; Müller, Franz-Josef; Koch, Philipp; Brüstle, Oliver


    Forced expression of proneural transcription factors has been shown to direct neuronal conversion of fibroblasts. Because neurons are postmitotic, conversion efficiencies are an important parameter for this process. We present a minimalist approach combining two-factor neuronal programming with small molecule-based inhibition of glycogen synthase kinase-3β and SMAD signaling, which converts postnatal human fibroblasts into functional neuron-like cells with yields up to >200% and neuronal purities up to >80%.

  13. Magnetic cooling from fundamentals to high efficiency refrigeration

    CERN Document Server

    Gutfleisch, Oliver


    This new publication is the first up-to-date resource on this exciting research area. As one of the few green, energy efficient technologies, magnetic cooling is experiencing a surge in interest and this book brings together the latest research from physics, materials science, engineering and chemistry. In the process of being commercialized, large organisations are working on bringing a suitable product to market utilising this technology.

  14. High Performance Healthcare Buildings: A Roadmap to Improved Energy Efficiency

    Energy Technology Data Exchange (ETDEWEB)

    Singer, Brett C.; Tschudi, William F.


    This document presents a road map for improving the energy efficiency of hospitals and other healthcare facilities. The report compiles input from a broad array of experts in healthcare facility design and operations. The initial section lists challenges and barriers to efficiency improvements in healthcare. Opportunities are organized around the following ten themes: understanding and benchmarking energy use; best practices and training; codes and standards; improved utilization of existing HVAC designs and technology; innovation in HVAC design and technology; electrical system design; lighting; medical equipment and process loads; economic and organizational issues; and the design of next generation sustainable hospitals. Achieving energy efficiency will require a broad set of activities including research, development, deployment, demonstration, training, etc., organized around 48 specific objectives. Specific activities are prioritized in consideration of potential impact, likelihood of near- or mid-term feasibility and anticipated cost-effectiveness. This document is intended to be broad in consideration though not exhaustive. Opportunities and needs are identified and described with the goal of focusing efforts and resources.

  15. [Evaluation of PNA-FISH method for direct identification of Candida species in blood culture samples and its potential impact on guidance of antifungal therapy]. (United States)

    Doğan, Özlem; İnkaya, Ahmet Çağkan; Gülmez, Dolunay; Uzun, Ömrüm; Akova, Murat; Arıkan Akdağlı, Sevtap


    Early antifungal therapy has a major influence on survival in candidemia. Rapid identification of the species has importance for the treatment, prediction of the species-specific primary resistance and variable antifungal susceptibility. Recently, molecular-based methods attempt to reduce the time between the positive signal of a blood culture and identification of the fungus. PNA-FISH (Peptide nucleic acid fluorescence in situ hybridization) assay distinguishes a number of frequently isolated Candida species in groups following the growth in blood culture. The aim of this study was to investigate the correlation of the species identified by PNA-FISH with conventional identification methods in yeast positive blood cultures and its influence on the selection of antifungal therapy. Specimens of adult patients diagnosed as yeast with Gram stain in signal-positive blood cultures between August to December 2013, were included in the study. The strains were concomitantly cultivated by subculturing from the blood culture bottles onto solid media and identified by conventional methods (germ tube test, ID32C and morphology on cornmeal Tween 80 agar). Rapid species identification was performed by Yeast Traffic Light PNA-FISH, which generates green flourescence for Candida albicans and Candida parapsilosis, yellow for Candida tropicalis, and red for Candida krusei and Candida glabrata. C.tropicalis was identified as a single species whereas the others were identified in pairs. The time points when the yeast positive blood culture bottle was received by the mycology laboratory and reporting of the species identification results by PNA-FISH and the conventional methods were recorded. Seven C.albicans, six C.glabrata, three C.parapsilosis, one C.tropicalis, one C.krusei, one Cryptococcus neoformans, one Saprochaete capitata (Blastoschizomyces capitatus), one C.albicans and Candida dubliniensis, one C.krusei and C.dubliniensis, and one C.glabrata and C.parapsilosis were

  16. Ka-Band TWT High-Efficiency Power Combiner for High-Rate Data Transmission (United States)

    Wintucky, Edwin G.; Simons, Rainee; Vaden, Karl R.; Lesny, Gary G.; Glass, Jeffrey L.


    A four-port magic-T hybrid waveguide junction serves as the central component of a high-efficiency two-way power combiner circuit for transmitting a high-rate phase-modulated digital signal at a carrier frequency in the Ka-band (between 27 and 40 GHz). This power combiner was developed to satisfy a specific requirement to efficiently combine the coherent outputs of two traveling-wavetube (TWT) amplifiers that are typically characterized by power levels on the order of 100 W or more. In this application, the use of a waveguide-based power combiner (instead of a coaxial-cable- or microstrip-based power combiner, for example) is dictated by requirements for low loss, high power-handling capability, and broadband response. Combiner efficiencies were typically 90 percent or more over both the linear and saturated output power regions of operation of the TWTs . Figure 1 depicts the basic configuration of the magic-T hybrid junction. The coherent outputs of the two TWTs enter through ports 1 and 4. As a result of the orientations of the electromagnetic fields, which also provides a needed high port-to-port isolation, of these two input signals and the interior design of the magic-T junction, the input powers are divided so as to add in phase at one output port (port 2), and to be opposite in phase and hence cancel each other at the opposite coplanar output port (port 3). The net result is that the output power at port 2 is essentially double that of the output of one TWT, minus the power lost in the magic-T hybrid junction. Optimum performance as a high-efficiency power combiner thus requires a balance of both power and phase at the input ports of the magic-T. Replicas of this two-way combiner can be arranged in a binary configuration to obtain a 2n-way (where n is an integer) combiner. For example, Figure 2 illustrates the use of three two-way combiners to combine the outputs of four TWTs.


    Gong, Qian


    Three IFS types currently used for optical design are: lenslet array, imager slicer, and lenslet array and fiber combined. Lenslet array based Integral Field Spectroscopy (IFS) is very popular for many astrophysics applications due to its compactness, simplicity, as well as cost and mass savings. The disadvantage of lenslet based IFS is its low detector pixel efficiency. Enough spacing is needed between adjacent spectral traces in cross dispersion direction to avoid wavelength cross-talk, because the same wavelength is not aligned to the same column on detector. Such as on a recent exoplanet coronagraph instrument study to support the coming astrophysics decadal survey (LUVOIR), to cover a 45 λ/D Field of View (FOV) with a spectral resolving power of 200 at shortest wavelength, a 4k x 4k detector array is needed. This large format EMCCD pushes the detector into technology development area with a low TRL. Besides the future mission, it will help WFIRST coronagraph IFS by packing all spectra into a smaller area on detector, which will reduce the chance for electrons to be trapped in pixels, and slow the detector degradation during the mission.The innovation we propose here is to increase the detector packing efficiency by grouping a number of lenslets together to form many mini slits. In other words, a number of spots (Point Spread Function at lenslet focus) are aligned into a line to resemble a mini slit. Therefore, wavelength cross-talk is no longer a concern anymore. This combines the advantage of lenslet array and imager slicer together. The isolation rows between spectral traces in cross dispersion direction can be reduced or removed. So the packing efficiency is greatly increased. Furthermore, the today’s microlithography and etching technique is capable of making such a lenslet array, which will relax the detector demand significantly. It will finally contribute to the habitable exoplanets study to analyzing their spectra from direct images. Detailed theory

  18. Design requirements for high-efficiency high concentration ratio space solar cells (United States)

    Rauschenbach, H.; Patterson, R.


    A miniaturized Cassegrainian concentrator system concept was developed for low cost, multikilowatt space solar arrays. The system imposes some requirements on solar cells which are new and different from those imposed for conventional applications. The solar cells require a circular active area of approximately 4 mm in diameter. High reliability contacts are required on both front and back surfaces. The back area must be metallurgically bonded to a heat sink. The cell should be designed to achieve the highest practical efficiency at 100 AMO suns and at 80 C. The cell design must minimize losses due to nonuniform illumination intensity and nonnormal light incidence. The primary radiation concern is the omnidirectional proton environment.

  19. Efficiency of the Compact Controlled High -Voltage Power Lines

    Directory of Open Access Journals (Sweden)

    Postolaty V.M.


    Full Text Available The basic theoretical principles to create compact controlled transmission lines are analyzed in the paper. The results of technical and project elaboration of some variants of such type of power transmission lines are presented and the comparison between their technical and economic indicators with those of traditional power transmission lines and foreign analogues is made in the paper. The efficiency of compact controlled transmission lines application to form power systems and to create intersystem ties as well as distribution electric network is also stated in the paper.

  20. Development of the ultra high efficiency thermal power generation facility

    Energy Technology Data Exchange (ETDEWEB)

    Sano, Toshihiro


    In order to prevent global warming, attention is focused on nuclear power generation and renewable energy such as wind and solar power generation. The electric power suppliers of Japan are aiming to increase the amount of nuclear and non-fossil fuel power generation over 50% of the total power generation by 2020. But this means that the remaining half will still be of thermal power generation using fossil fuel and will still play an important role. Under such circumstances, further efficiency improvement of the thermal power generation and its aggressive implementation is ongoing in Japan.

  1. Designing High Efficient Solar Powered OLED Lighting Systems

    DEFF Research Database (Denmark)

    Ploug, Rasmus Overgaard; Poulsen, Peter Behrensdorff; Thorsteinsson, Sune


    for the 10 Wp version. Furthermore, we present measurements of state-of-the-art commercial available OLED with regards to the luminous flux, luminous efficacy, luminance homogeneity, temperature dependency and IV characteristic of the OLED panels. In addition, solar powered OLED product concepts are proposed.......OLEDs used in solar powered lighting applications is a market of the future. This paper reports the development of electronic Three-Port-Converters for PV OLED product integration in the low-power area respectively for 1-10 Wp and 10-50 Wp with a peak efficiency of 97% at 1.8 W of PV power...

  2. Modulation of mdm2 pre-mRNA splicing by 9-aminoacridine-PNA (peptide nucleic acid conjugates targeting intron-exon junctions

    Directory of Open Access Journals (Sweden)

    Nielsen Peter E


    Full Text Available Abstract Background Modulation of pre-mRNA splicing by antisense molecules is a promising mechanism of action for gene therapeutic drugs. In this study, we have examined the potential of peptide nucleic acid (PNA 9-aminoacridine conjugates to modulate the pre-mRNA splicing of the mdm2 human cancer gene in JAR cells. Methods We screened 10 different 15 mer PNAs targeting intron2 at both the 5' - and the 3'-splice site for their effects on the splicing of mdm2 using RT-PCR analysis. We also tested a PNA (2512 targeting the 3'-splice site of intron3 with a complementarity of 4 bases to intron3 and 11 bases to exon4 for its splicing modulation effect. This PNA2512 was further tested for the effects on the mdm2 protein level as well as for inhibition of cell growth in combination with the DNA damaging agent camptothecin (CPT. Results We show that several of these PNAs effectively inhibit the splicing thereby producing a larger mRNA still containing intron2, while skipping of exon3 was not observed by any of these PNAs. The most effective PNA (PNA2406 targeting the 3'-splice site of intron2 had a complementarity of 4 bases to intron2 and 11 bases to exon3. PNA (2512 targeting the 3'-splice site of intron3 induced both splicing inhibition (intron3 skipping and skipping of exon4. Furthermore, treatment of JAR cells with this PNA resulted in a reduction in the level of MDM2 protein and a concomitant increase in the level of tumor suppressor p53. In addition, a combination of this PNA with CPT inhibited cell growth more than CPT alone. Conclusion We have identified several PNAs targeting the 5'- or 3'-splice sites in intron2 or the 3'-splice site of intron3 of mdm2 pre-mRNA which can inhibit splicing. Antisense targeting of splice junctions of mdm2 pre-mRNA may be a powerful method to evaluate the cellular function of MDM2 splice variants as well as a promising approach for discovery of mdm2 targeted anticancer drugs.

  3. High efficiency gears synthesis by avoid the interferences

    Directory of Open Access Journals (Sweden)

    Florian Ion Tiberiu Petrescu


    Full Text Available Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 The paper presents an original method to determine the efficiency of the gear, the forces of the gearing, the velocities and the powers. It is analyzing the influence of a few parameters concerning gear efficiency. These parameters are: z1 - the number of teeth for the primary wheel of gear; z2 - the number of teeth of the secondary wheel of gear; alpha0 - the normal pressure angle on the divided circle; beta - the inclination angle. With the relations presented in this paper, it can synthesize the gear’s mechanisms. Today, the gears are present everywhere, in the mechanical’s world (In vehicle’s industries, in electronics and electro-technique equipments, in energetically industries, etc. Optimizing this mechanism (the gears mechanism, we can improve the functionality of the transmissions with gears. At the gear mechanisms an important problem is the interference of the teeth. To avoid the interference between teeth, we must know the minimum number of teeth of the driving wheel, in function of the pressure angle (normal on the pitch circle, alpha0, in function of the tooth inclination angle (beta, and in function of the transmission ratio (i.

  4. PNA-mediated modulation and redirection of Her-2 pre-mRNA splicing: specific skipping of erbB-2 exon 19 coding for the ATP catalytic domain

    DEFF Research Database (Denmark)

    Pankratova, Stanislava; Nielsen, Birgit N; Shiraishi, Takehiko


    interference as a means of manipulating erbB-2 expression in a therapeutically relevant fashion, we have studied the effect on mRNA splicing of a series of peptide nucleic acid (PNA) oligomers targeting specific intron-exon junctions in the erbB-2 pre-mRNA. In particular, we are interested in identifying PNA...

  5. Orientation Preferences of Backbone Secondary Amide Functional Groups in Peptide Nucleic Acid Complexes: Quantum Chemical Calculations Reveal an Intrinsic Preference of Cationic D-Amino Acid-Based Chiral PNA Analogues for the P-form

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Jeremy C [ORNL; Topham, Christopher [University of Heidelberg


    Geometric descriptions of nonideal interresidue hydrogen bonding and backbone-base water bridging in the minor groove are established in terms of polyamide backbone carbonyl group orientation from analyses of residue junction conformers in experimentally determined peptide nucleic acid (PNA) complexes. Two types of interresidue hydrogen bonding are identified in PNA conformers in heteroduplexes with nucleic acids that adopt A-like base pair stacking. Quantum chemical calculations on the binding of a water molecule to an O2 base atom in glycine-based PNA thymine dimers indicate that junctions modeled with P-form backbone conformations are lower in energy than a dimer comprising the predominant conformation observed in A-like helices. It is further shown in model systems that PNA analogs based on D-lysine are better able to preorganize in a conformation exclusive to P-form helices than is glycine-based PNA. An intrinsic preference for this conformation is also exhibited by positively charged chiral PNA dimers carrying 3-amino-D-alanine or 4-aza-D-leucine residue units that provide for additional rigidity by side-chain hydrogen bonding to the backbone carbonyl oxygen. Structural modifications stabilizing P-form helices may obviate the need for large heterocycles to target DNA pyrimidine bases via PNADNA-PNA triplex formation. Quantum chemical modeling methods are used to propose candidate PNA Hoogsteen strand designs.

  6. Environmentally Printing Efficient Organic Tandem Solar Cells with High Fill Factors: A Guideline Towards 20% Power Conversion Efficiency

    DEFF Research Database (Denmark)

    Li, Ning; Baran, Derya; Spyropoulos, George D.


    The tandem concept involves stacking two or more cells with complementary absorption spectra in series or parallel connection, harvesting photons at the highest possible potential. It is strongly suggested that the roll-to-roll production of organic solar cells will employ the tandem concept...... to enhance the power conversion efficiency (PCE). However, due to the undeveloped deposition techniques, the challenges in ink formulation as well as the lack of commercially available high performance active materials, roll-to-roll fabrication of highly efficient organic tandem solar cells currently...... presents a major challenge. The reported high PCE values from lab-scale spin-coated devices are, of course, representative, but not helpful for commercialization. Here, organic tandem solar cells with exceptionally high fill factors and PCE values of 7.66% (on glass) and 5.56% (on flexible substrate...

  7. High Efficiency Hall Thruster Discharge Power Converter Project (United States)

    National Aeronautics and Space Administration — Busek leveraged previous, internally sponsored, high power, Hall thruster discharge converter development which allowed it to design, build, and test new printed...

  8. Comprehensive Assessment of the Potential for Efficient District Heating and Cooling and for High-Efficient Cogeneration in Austria

    Directory of Open Access Journals (Sweden)

    Richard Büchele


    Full Text Available In accordance with the EU Energy Efficiency Directive all Member States have to develop a comprehensive assessment of the potential for high-efficient CHP and efficient district heating and cooling by the end of 2015. This paper describes the approach and methodology used to determine the district heating potentials for Austria. In a first step actual and future heating and cooling demand in the building sector is evaluated using the techno-economic bottom-up model Invert/EE-Lab. Relevant infrastructure probably existing in 2025 is investigated and included into the analysis. Technical potentials for efficient technologies are calculated. After a classification of relevant regions into main and secondary regions a country-level cost-benefit-analysis is performed. The results indicate that there is a reasonable additional potential for district heating by the year 2025 under our central scenario assumptions and within sensitivity scenarios. Only in scenarios with high CO2-price or low gas price, CHP is an economically efficient solution to supply district heat.

  9. High Efficiency PFC Frontend for Class-D Amplifiers

    DEFF Research Database (Denmark)

    Li, Qingnan; Frium, Mads P.


    This thesis investigates the design of high eciency Power Factor Correction (PFC) converter for Class-D amplier at universal line and 3.5kW power range. The work starts with an overview on dierent high eciency Bridgeless PFC topologies and investigates their applicability with respect to the give...

  10. Highly efficient solvent-free synthesis of pyranopyrazoles by a ...

    Indian Academy of Sciences (India)

    components and show high atom economy and high selectivity.1,2 MCRs have great contribution in con- vergent synthesis of complex and important organic molecules from simple and readily available starting materials, and have emerged as powerful tools for drug discovery.3,4 The pyranopyrazole nucleus is a fer-.

  11. Energy Efficient Beam Transfer Channels for High Energy Particle Accelerators

    CERN Document Server

    Gardlowski, Philipp; Ondreka, David


    conducting (NC) magnets or high current pulsed (HCP) magnets are an economic solution. For high repetition rates above 1.0 Hz, superconducting Cos(N) (SC) magnets or superferric (SF) magnets are more attractive; at least if they are operated in DC mode and if no dynamic losses occur in the cryogenic system. Unfortunately, a range between these values exist, in which no...

  12. Beef-derived Mesoporous Carbon as Highly Efficient Support for ...

    African Journals Online (AJOL)

    In this work, a low-cost and nitrogen-containing carbon with mesoporous pores and high surface area was synthesized by carbonizing a natural biomass precursor, i.e. beef. It is found that the prepared material has excellent textural properties such as high specific surface areas and large pore diameters. TEM images ...

  13. Highly efficient multifunctional metasurface for high-gain lens antenna application (United States)

    Hou, Haisheng; Wang, Guangming; Li, Haipeng; Guo, Wenlong; Li, Tangjing


    In this paper, a novel multifunctional metasurface combining linear-to-circular polarization conversion and electromagnetic waves focusing has been proposed and applied to design a high-gain lens antenna working at Ku band. The multifunctional metasurface consists of 15 × 15 unit cells. Each unit cell is composed of four identical metallic layers and three intermediate dielectric layers. Due to well optimization, the multifunctional metasurface can convert the linearly polarized waves generated by the source to circularly polarized waves and focus the waves. By placing a patch antenna operating at 15 GHz at the focal point of the metasurface and setting the focal distance to diameter ratio ( F/ D) to 0.34, we obtain a multifunctional lens antenna. Simulated and measured results coincide well, indicating that the metasurface can convert linearly polarized waves to right-handed circularly polarized waves at 15 GHz with excellent performances in terms of the 3 dB axial ratio bandwidth of 5.3%, realized gain of 16.9 dB and aperture efficiency of 41.2%. Because of the advantages of high gain, competitive efficiency and easy fabrication, the proposed lens antenna has a great potential application in wireless and satellite communication.

  14. Optimized shielded-gate trench MOSFET technology for high-frequency, high-efficiency power supplies (United States)

    Challa, Ashok; Sarkar, Tirthajyoti; Sapp, Steven


    Shielded-gate trench-MOSFETs yield superior performance compared to conventional gate trench devices by allowing higher doping density in the drift region and providing a `shielding effect' for the gate by placing an intermediate electrode between gate and drain. However, further design optimizations can be done for a shieldedgate trench-MOSFET to improve performance parameters particularly suited for next-generation high-frequency computing power supply applications and they have been outlined in this article. Channel optimization, substrate thinning and intrinsic gate resistance reduction (by layout enhancements) have been discussed along with their impact on cost-performance benefit on the device. Further, effects of these design optimizations on the power loss and efficiency of a high-frequency switching converter have been demonstrated by mixed device-circuit simulations.

  15. Environmental friendly high efficient light source plasma lamp - Final report

    Energy Technology Data Exchange (ETDEWEB)

    Courret, G.; Calame, L. [Haute Ecole d' ingenierie et de gestion du canton de Vaud, Institut de micro et nano techniques, Yverdon-les-Bains (Switzerland); Meyer, A. [Solaronix SA, Aubonne (Switzerland)


    This illustrated final report for the Swiss Federal Office of Energy (SFOE) takes a look at work done on the development of a sulphur-based plasma lamp. In 2007, the capability of a new modulator has been explored. The most important results are discussed. With the production of a 1.2 cm{sup 3} bulb, the way towards the production of a 100 W lamp has been opened. The authors comment that modulation by impulses increases the luminous efficiency in comparison to modulation using a continuous sinusoidal wave. The report deals with the history of the project, the development of the new modulator, the use of rotational effects and the optimisation of the amount of active substances - tellurium and selenium - in the bulb. The electromagnetic coupling system used is described and discussed.

  16. High efficiency Lifter based on the Biefeld-Brown effect

    Directory of Open Access Journals (Sweden)

    Moshe Einat


    Full Text Available The Biefeld-Brown is a fascinating effect with which levitation can be reached without moving or rotating elements. Static voltage is applied between asymmetric electrodes and a force towards the small electrode is generated. This effect is studied experimentally in this paper. Using this effect a set of experiments is conducted trying to clarify the relation of the model geometry to the induced force. The results show clear relations of the generated force to the model structure and dimensions. As the asymmetry is stronger, the force is stronger. According to the experimental results, a set of preferred parameters is given to strength the effect. Choosing the geometrical properties properly led to improvement of factor ∼9 in the generated force and efficiency. Nevertheless, some results provides contradictions to earlier models of electrohydrodynamicmic (EHD describing the effect and reveal unresolved questions regarding this effect.

  17. Dry Epitaxial Lift-Off for High Efficiency Solar Cells Project (United States)

    National Aeronautics and Space Administration — A new method of transferring epitaxially grown active films onto an inexpensive polymeric flexible carrier. Specifically, for making thin lightweight high efficiency...

  18. High Efficiency Quantum Well Waveguide Solar Cells Project (United States)

    National Aeronautics and Space Administration — The long-term objective of this program is to develop flexible, lightweight, single-junction solar cells using quantum structured designs that can achieve ultra-high...

  19. Telomerase efficiently elongates highly transcribing telomeres in human cancer cells.

    Directory of Open Access Journals (Sweden)

    Benjamin O Farnung

    Full Text Available RNA polymerase II transcribes the physical ends of linear eukaryotic chromosomes into a variety of long non-coding RNA molecules including telomeric repeat-containing RNA (TERRA. Since TERRA discovery, advances have been made in the characterization of TERRA biogenesis and regulation; on the contrary its associated functions remain elusive. Most of the biological roles so far proposed for TERRA are indeed based on in vitro experiments carried out using short TERRA-like RNA oligonucleotides. In particular, it has been suggested that TERRA inhibits telomerase activity. We have exploited two alternative cellular systems to test whether TERRA and/or telomere transcription influence telomerase-mediated telomere elongation in human cancer cells. In cells lacking the two DNA methyltransferases DNMT1 and DNMT3b, TERRA transcription and steady-state levels are greatly increased while telomerase is able to elongate telomeres normally. Similarly, telomerase can efficiently elongate transgenic inducible telomeres whose transcription has been experimentally augmented. Our data challenge the current hypothesis that TERRA functions as a general inhibitor of telomerase and suggest that telomere length homeostasis is maintained independently of TERRA and telomere transcription.

  20. Highly efficient vitrification method for cryopreservation of human oocytes. (United States)

    Kuwayama, Masashige; Vajta, Gábor; Kato, Osamu; Leibo, Stanley P


    Two experiments were performed to develop a method to cryopreserve MII human oocytes. In the first experiment, three vitrification methods were compared using bovine MII oocytes with regard to their developmental competence after cryopreservation: (i) vitrification within 0.25-ml plastic straws followed by in-straw dilution after warming (ISD method); (ii) vitrification in open-pulled straws (OPS method); and (iii) vitrification in plastic handle (Cryotop method). In the second experiment, the Cryotop method, which had yielded the best results, was used to vitrify human oocytes. Out of 64 vitrified oocytes, 58 (91%) exhibited normal morphology after warming. After intracytoplasmic sperm injection, 52 became fertilized, and 32 (50%) developed to the blastocyst stage in vitro. Analysis by fluorescence in-situ hybridization of five blastocysts showed that all were normal diploid embryos. Twenty-nine embryo transfers with a mean number of 2.2 embryos per transfer on days 2 and 5 resulted in 12 initial pregnancies, seven healthy babies and three ongoing pregnancies. The results suggest that vitrification using the Cryotop is the most efficient method for human oocyte cryopreservation.

  1. Efficiency of protective coatings on high creep resistant cast steel

    Directory of Open Access Journals (Sweden)

    J. Kubicki


    Full Text Available This paper presents results of research of multilayer aluminium–silicon coatings. Aluminium–silicon coatings were created on high–temperature creep resist cast iron using slurry method in air atmosphere. These coatings protect equipment against hot corrosionin carburizing atmosphere at thermal shocks conditions.Various technological parameters of coatings manufacturing were applied. Main technological parameters were: temperature and time ofannealing and Al-Si ratio in the active mixture. The structure of obtained coatings is three-zonal. Phase composition of two external zones ensures protection against carburizing, but these zones are not resistant to cracking. The cracks form as a result of thermal shocks. The internal zone of the coatings situated next to substrate compensates for differences of thermal expansion of the coating and the substrate. The cracks are stopped in the internal zone and do not propagate into the substrate material. Protective efficiency of the coatings at carburizing conditions with thermal shocks was determined. Structure of the coatings before and after carburizing and thermal shocks is described in present paper. Thickness, chemical composition (EDS and phase composition (XRD of the coatings are determined. Correlation between the coatings structure and depth of carburized layer was determined.

  2. SWORD-a highly efficient protein database search. (United States)

    Vaser, Robert; Pavlović, Dario; Šikić, Mile


    Protein database search is one of the fundamental problems in bioinformatics. For decades, it has been explored and solved using different exact and heuristic approaches. However, exponential growth of data in recent years has brought significant challenges in improving already existing algorithms. BLAST has been the most successful tool for protein database search, but is also becoming a bottleneck in many applications. Due to that, many different approaches have been developed to complement or replace it. In this article, we present SWORD, an efficient protein database search implementation that runs 8-16 times faster than BLAST in the sensitive mode and up to 68 times faster in the fast and less accurate mode. It is designed to be used in nearly all database search environments, but is especially suitable for large databases. Its sensitivity exceeds that of BLAST for majority of input datasets and provides guaranteed optimal alignments. Sword is freely available for download from and Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail:

  3. Thermoelectric materials - Compromising between high efficiency and materials abundance

    Energy Technology Data Exchange (ETDEWEB)

    Homm, G.; Klar, P.J. [I. Physikalisches Institut, Justus-Liebig-Universitaet, Heinrich-Buff-Ring 16, 35392 Giessen (Germany)


    In the context of CO{sub 2} neutral and regenerative energy production, the field of thermoelectrics has shifted more and more into the focus of scientific research in the last few years. Particularly a lot of research projects were started in the field of energy autarkic sensor technology and the so called energy harvesting, i.e. the recycling of otherwise lost energy. A potentially huge industrial branch for thermoelectric applications is the automotive industry with a main emphasis on generating electricity out of the waste heat of combustion engines with the help of thermoelectric generators or using Peltier cooling to replace conventional air conditioning in the passenger compartment. In addition, many niche applications are possible, e.g. as sensors for measuring the air pressure of tires etc. The applications of thermoelectric devices are very versatile. We analyse the potential of the state-of-the-art thermoelectric materials SiGe, PbTe, Bi{sub 2}Te{sub 3}, FeSi{sub 2} and potentially ZnO with respect to employment in four types of applications, classified by mobile vs stationary and specialized vs. mass application. The selection criteria comprise efficiency, materials availability, costs, environmental friendliness and toxicity. Based on these criteria, a decision matrix for choosing the appropriate material system for a specific application is defined. (copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  4. High-Efficiency BODIPY-Based Organic Photovoltaics

    KAUST Repository

    Chen, John J.


    © 2014 American Chemical Society. A benzannulated boron dipyrromethene (BODIPY, bDIP) molecule exhibiting strong absorption at 640 nm was synthesized. The organic dye was used in an organic solar cell as the electron donor with C60 as the acceptor. The BODIPY dye demonstrated the best performance in lamellar architecture (indium tin oxide (ITO)/bDIP/C60/bathocuproine/Al), giving power conversion efficiency up to 4.5% with short-circuit current (JSC) of 8.7 mA/cm2 and an open-circuit voltage (VOC) of 0.81 V. Neutron reflectivity experiments were performed on the bilayer film to investigate the thickness dependence of JSC. A 13 nm mixed layer was found to be present at the donor/acceptor interface in the bilayer device, formed when the C60 was deposited onto a room temperature bDIP film. Planar-mixed heterojunction devices were fabricated to understand the extent of spontaneous mixing between the donor and acceptor materials. The native mixed region in the bilayer device was shown to most resemble 1:3 bDIP:C60 layer in the structure: (ITO/bDIP/bDIP:C60 blend/C60/bathocuproine/Al).

  5. Molecular and Nanoscale Engineering of High Efficiency Excitonic Solar Cells

    Energy Technology Data Exchange (ETDEWEB)

    Jenekhe, Samson A. [Univ. of Washington, Seattle, WA (United States); Ginger, David S. [Univ. of Washington, Seattle, WA (United States); Cao, Guozhong [Univ. of Washington, Seattle, WA (United States)


    We combined the synthesis of new polymers and organic-inorganic hybrid materials with new experimental characterization tools to investigate bulk heterojunction (BHJ) polymer solar cells and hybrid organic-inorganic solar cells during the 2007-2010 period (phase I) of this project. We showed that the bulk morphology of polymer/fullerene blend solar cells could be controlled by using either self-assembled polymer semiconductor nanowires or diblock poly(3-alkylthiophenes) as the light-absorbing and hole transport component. We developed new characterization tools in-house, including photoinduced absorption (PIA) spectroscopy, time-resolved electrostatic force microscopy (TR-EFM) and conductive and photoconductive atomic force microscopy (c-AFM and pc-AFM), and used them to investigate charge transfer and recombination dynamics in polymer/fullerene BHJ solar cells, hybrid polymer-nanocrystal (PbSe) devices, and dye-sensitized solar cells (DSSCs); we thus showed in detail how the bulk photovoltaic properties are connected to the nanoscale structure of the BHJ polymer solar cells. We created various oxide semiconductor (ZnO, TiO2) nanostructures by solution processing routes, including hierarchical aggregates and nanorods/nanotubes, and showed that the nanostructured photoanodes resulted in substantially enhanced light-harvesting and charge transport, leading to enhanced power conversion efficiency of dye-sensitized solar cells.

  6. A high-efficiency Si-detector array for HELIOS (United States)

    Back, B. B.; Digiovine, B.; Heimsath, S.; James, A. M.; Hoffman, C. R.; Kay, B. P.; Rogers, A. M.; Schiffer, J. P.; Wuosmaa, A. H.; Lighthall, J. C.; Marley, S. T.


    HELIOS at ATLAS consists of a large superconducting solenoid with its magnetic axis aligned with the beam. Light charged particles emitted from the target are bent in helical orbits back to the axis where their energy and point of impact are measured by a position-sensitive Si-detector array to fully characterize two-body reactions [1]. Using an array assembled from a set of 24 Si wafers from an earlier project, this spectrometer has been in operation since August 2008 [2,3]. We will discuss the challenges in designing a new, optimized Si detector configuration that simultaneously allows for the beam to enter the spectrometer through a large bore in the upstream array, kinematic recoil detection through the bore of the downstream array, liquid cooling of the Si wafers, optimal efficiency, and the possibility of replacing individual Si wafers in the case of failure. [1] A.H. Wuosmaa et al., Nucl. Inst. Meth. A 580, 1290 (2007) [2] B.B. Back et al., Phys. Rev. Lett. 104, 132501 (2010) [3] J.C. Lighthall et al., Submitted to Nucl. Instr. Meth. (May 2010)

  7. High efficiency off-axis current drive by high frequency fast waves

    Energy Technology Data Exchange (ETDEWEB)

    Prater, R.; Pinsker, R. I.; Moeller, C. P. [General Atomics, PO Box 85608, San Diego, California 92186-5608 (United States); Porkolab, M.; Vdovin, V. [Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, Massachusetts 02139 (United States)


    Modeling work shows that current drive can be done off-axis with high efficiency, as required for FNSF and DEMO, by using very high harmonic fast waves (“helicons” or “whistlers”). The modeling indicates that plasmas with high electron beta are needed in order for the current drive to take place off-axis, making DIII-D a highly suitable test vehicle for this process. The calculations show that the driven current is not very sensitive to the launched value of n{sub ∥}, a result that can be understood from examination of the evolution of n{sub ∥} as the waves propagate in the plasma. Because of this insensitivity, relatively large values (∼3) of n{sub ∥} can be launched, thereby avoiding some of the problems with mode conversion in the boundary found in some previous experiments. Use of a traveling wave antenna provides a very narrow n{sub ∥} spectrum, which also helps avoid mode conversion.

  8. Efficient Management of High-Throughput Screening Libraries with SAVANAH

    DEFF Research Database (Denmark)

    List, Markus; Elnegaard, Marlene Pedersen; Schmidt, Steffen


    High-throughput screening (HTS) has become an indispensable tool for the pharmaceutical industry and for biomedical research. A high degree of automation allows for experiments in the range of a few hundred up to several hundred thousand to be performed in close succession. The basis for such scr......High-throughput screening (HTS) has become an indispensable tool for the pharmaceutical industry and for biomedical research. A high degree of automation allows for experiments in the range of a few hundred up to several hundred thousand to be performed in close succession. The basis...... for such screens are molecular libraries, that is, microtiter plates with solubilized reagents such as siRNAs, shRNAs, miRNA inhibitors or mimics, and sgRNAs, or small compounds, that is, drugs. These reagents are typically condensed to provide enough material for covering several screens. Library plates thus need...... to be serially diluted before they can be used as assay plates. This process, however, leads to an explosion in the number of plates and samples to be tracked. Here, we present SAVANAH, the first tool to effectively manage molecular screening libraries across dilution series. It conveniently links (connects...

  9. High-efficient low-cost photovoltaics: recent developments

    National Research Council Canada - National Science Library

    Petrova-Koch, Vesselinka; Hezel, Rudolf; Goetzberger, A


    ... and dynamically growing branches of the industry at the moment. Although today the cost of PV is still relatively high, it has dropped considerably in the past years and will continue to do so. A main driving force behind the development of solar energy is its enormous, practically unlimited potential. Unlike other renewable energy sources ...

  10. Beef-derived Mesoporous Carbon as Highly Efficient Support for ...

    African Journals Online (AJOL)


    PtRuIr/C-Beef was highly active for methanol electro-oxidation. PtRuIr/C-Beef showed superior catalytic ... Carbon materials, electrocatalysts, support, beef, methanol oxidation. 1. Introduction. The binary PtRu alloy is ..... support for electrocatalysts used in direct methanol fuel cells. Acknowledgements. The authors would ...

  11. Highly efficient catalytic reductive degradation of various organic ...

    Indian Academy of Sciences (India)

    by conventional water treatment processes due to their complex aromatic structures, hydrophilic nature and high stability against light, temperature, water, chem- icals, etc.1,2 In this view, degradation of organic dye molecules in waste water has gained paramount atten- tion.1,3 Till date, several techniques such as physical.

  12. HASE: Framework for efficient high-dimensional association analyses

    NARCIS (Netherlands)

    G.V. Roshchupkin (Gennady); H.H.H. Adams (Hieab); M.W. Vernooij (Meike); A. Hofman (Albert); C.M. van Duijn (Cornelia); M.K. Ikram (Kamran); W.J. Niessen (Wiro)


    textabstractHigh-throughput technology can now provide rich information on a person's biological makeup and environmental surroundings. Important discoveries have been made by relating these data to various health outcomes in fields such as genomics, proteomics, and medical imaging. However,

  13. HASE : Framework for efficient high-dimensional association analyses

    NARCIS (Netherlands)

    Roshchupkin, G. V.; Adams, H; Vernooij, Meike W.; Hofman, A; Van Duijn, C. M.; Ikram, M. Arfan; Niessen, W.J.


    High-throughput technology can now provide rich information on a person's biological makeup and environmental surroundings. Important discoveries have been made by relating these data to various health outcomes in fields such as genomics, proteomics, and medical imaging. However,

  14. Highly efficient deep ultraviolet generation by sum-frequency mixing ...

    Indian Academy of Sciences (India)

    Generation of deep ultraviolet radiation at 210 nm by Type-I third harmonic generation is achieved in a pair of BBO crystals with conversion efficiency as high as 36%. The fundamental source is the dye laser radiation pumped by the second harmonic of a Q-switched Nd : YAG laser. A walk-off compensated configuration ...

  15. Novel Semiconducting Polymers for Highly Efficient Solar Energy Harvesting (United States)


    rooftops of buildings. However, the cost of these devices is still too high to be economically viable. 2 The urgency of securing sustainable...inorganic counterparts. 4 So far, the most successful architecture to build organic photovoltaic solar cells is the BHJ structure prepared by

  16. High-throughput genomics enhances tomato breeding efficiency. (United States)

    Barone, A; Di Matteo, A; Carputo, D; Frusciante, L


    Tomato (Solanum lycopersicum) is considered a model plant species for a group of economically important crops, such as potato, pepper, eggplant, since it exhibits a reduced genomic size (950 Mb), a short generation time, and routine transformation technologies. Moreover, it shares with the other Solanaceous plants the same haploid chromosome number and a high level of conserved genomic organization. Finally, many genomic and genetic resources are actually available for tomato, and the sequencing of its genome is in progress. These features make tomato an ideal species for theoretical studies and practical applications in the genomics field. The present review describes how structural genomics assist the selection of new varieties resistant to pathogens that cause damage to this crop. Many molecular markers highly linked to resistance genes and cloned resistance genes are available and could be used for a high-throughput screening of multiresistant varieties. Moreover, a new genomics-assisted breeding approach for improving fruit quality is presented and discussed. It relies on the identification of genetic mechanisms controlling the trait of interest through functional genomics tools. Following this approach, polymorphisms in major gene sequences responsible for variability in the expression of the trait under study are then exploited for tracking simultaneously favourable allele combinations in breeding programs using high-throughput genomic technologies. This aims at pyramiding in the genetic background of commercial cultivars alleles that increase their performances. In conclusion, tomato breeding strategies supported by advanced technologies are expected to target increased productivity and lower costs of improved genotypes even for complex traits.

  17. Establishment of a high-efficiency plant regeneration and ...

    African Journals Online (AJOL)



    Oct 5, 2009 ... differentiated into plants, in spite of high CIP. Maize inbred line 18-599(red) as a ... bombardment, after selection and differentiation culture, partial bombarded calli were regenerated into green plantlets and further .... described in the manufacturer's instructions, with 1100 psi helium pressure and a target ...

  18. Efficient high-order suppression system for a metrology beamline. (United States)

    Sokolov, A; Sertsu, M G; Gaupp, A; Lüttecke, M; Schäfers, F


    High-quality metrology with synchrotron radiation requires in particular a very high spectral purity of the incident beam. This is usually achieved by a set of transmission filters with suitable absorption edges to suppress high-order radiation of the monochromator. The at-wavelength metrology station at a BESSY-II bending-magnet collimated plane-grating monochromator (c-PGM) beamline has recently commissioned a high-order suppression system (HiOS) based on four reflections from mirrors which can be inserted into the beam path. Two pairs of mirrors are aligned parallel so as not to disturb the original beam path and are rotated clockwise and counter-clockwise. Three sets of coatings are available for the different energy ranges and the incidence angle is freely tunable to find the optimum figure of merit for maximum suppression at maximum transmission for each photon energy required. Measured performance results of the HiOS for the EUV and XUV range are compared with simulations, and applications are discussed.

  19. Designing large, high-efficiency, high-numerical-aperture, transmissive meta-lenses for visible light

    CERN Document Server

    Byrnes, Steven J; Aieta, Francesco; Capasso, Federico


    A metasurface lens (meta-lens) is a lens that bends light with an array of nanostructures on a flat surface, rather than by refraction. Macroscopic meta-lenses (mm- to cm-scale diameter) have been quite difficult to simulate and optimize, due to the large area, the lack of periodicity, and the billions of adjustable parameters. We describe a method for designing a large-area meta-lens that allows not only prediction of the efficiency and far-field, but also optimization of the shape and position of each individual nanostructure, with a computational cost that is almost independent of the lens size. Loosely speaking, the technique consists of designing a series of metasurface beam deflectors (blazed gratings), and then gluing them together. As a test of this framework, we design some high-numerical-aperture (NA=0.94) meta-lenses for visible light, based on TiO2 nano-pillars on a glass substrate. One of our designs is predicted to focus unpolarized 580nm light with 79% predicted efficiency; another focuses 580n...

  20. Highly efficient adsorption of chlorophenols onto chemically modified chitosan

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, Liang-Chun [Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064 (China); National Center for Packaging Material Quality Supervision and Inspection, Chengdu Institute of Product Quality Supervision and Inspection, Chengdu 610064 (China); Meng, Xiang-Guang, E-mail: [Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064 (China); Fu, Jing-Wei [National Center for Packaging Material Quality Supervision and Inspection, Chengdu Institute of Product Quality Supervision and Inspection, Chengdu 610064 (China); Yang, Yu-Chong; Yang, Peng; Mi, Chun [Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064 (China)


    A novel chemically modified chitosan CS-SA-CD with phenol and β-cyclodextrin groups was prepared. The adsorptions of phenol, 2-chlorophenol (2-CP), 4-chlorophenol (4-CP), 2,4-dichlorophenol (DCP) and 2,4,6-trichlorophenol (TCP) on the functional chitosan from aqueous solution were investigated. CS-SA-CD exhibited excellent adsorption ability for chlorophenols especially for DCP and TCP. The maximum adsorption capacities of phenol, 2-CP, 4-CP, DCP and TCP on CS-SA-CD were 59.74, 70.52, 96.43, 315.46 and 375.94 mg/g, respectively. The scanning electron microscope and Brunauer–Emmett–Teller analyses revealed that the introduction of phenol group changed the surface morphology and surface properties of chitosan. The modified chitosan CS-SA-CD possesses larger surface areas (4.72 m{sup 2}/g), pore volume (7.29 × 10{sup −3} mL/g) and average pore diameter (59.99 Å) as compared to those of chitosan 3.27 m{sup 2}/g, 2.00 × 10{sup −3} mL/g and 15.95 Å, respectively. The enhanced adsorption of chlorophenols was also attributed to the interaction of hydrogen bond between Cl atom and -OH group. The adsorption of chlorophenols on CS-SA-CD followed the pseudo-second-order kinetic model. Adsorbent could be regenerated easily and the regenerated CS-SA-CD remained 80–91% adsorption efficiency.

  1. Discriminating multi-species populations in biofilms with peptide nucleic acid fluorescence in situ hybridization (PNA FISH). (United States)

    Almeida, Carina; Azevedo, Nuno F; Santos, Sílvio; Keevil, Charles W; Vieira, Maria J


    Our current understanding of biofilms indicates that these structures are typically composed of many different microbial species. However, the lack of reliable techniques for the discrimination of each population has meant that studies focusing on multi-species biofilms are scarce and typically generate qualitative rather than quantitative data. We employ peptide nucleic acid fluorescence in situ hybridization (PNA FISH) methods to quantify and visualize mixed biofilm populations. As a case study, we present the characterization of Salmonella enterica/Listeria monocytogenes/Escherichia coli single, dual and tri-species biofilms in seven different support materials. Ex-situ, we were able to monitor quantitatively the populations of ∼56 mixed species biofilms up to 48 h, regardless of the support material. In situ, a correct quantification remained more elusive, but a qualitative understanding of biofilm structure and composition is clearly possible by confocal laser scanning microscopy (CLSM) at least up to 192 h. Combining the data obtained from PNA FISH/CLSM with data from other established techniques and from calculated microbial parameters, we were able to develop a model for this tri-species biofilm. The higher growth rate and exopolymer production ability of E. coli probably led this microorganism to outcompete the other two [average cell numbers (cells/cm(2)) for 48 h biofilm: E. coli 2,1 × 10(8) (± 2,4 × 10(7)); L. monocytogenes 6,8 × 10(7) (± 9,4 × 10(6)); and S. enterica 1,4 × 10(6) (± 4,1 × 10(5))]. This overgrowth was confirmed by CSLM, with two well-defined layers being easily identified: the top one with E. coli, and the bottom one with mixed regions of L. monocytogenes and S. enterica. While PNA FISH has been described previously for the qualitative study of biofilm populations, the present investigation demonstrates that it can also be used for the accurate quantification and spatial distribution of species in polymicrobial communities

  2. High Efficiency Acetylcholinesterase Immobilization on DNA Aptamer Modified Surfaces

    Directory of Open Access Journals (Sweden)

    Orada Chumphukam


    Full Text Available We report here the in vitro selection of DNA aptamers for electric eel acetylcholinesterase (AChE. One selected aptamer sequence (R15/19 has a high affinity towards the enzyme (Kd = 157 ± 42 pM. Characterization of the aptamer showed its binding is not affected by low ionic strength (~20 mM, however significant reduction in affinity occurred at high ionic strength (~1.2 M. In addition, this aptamer does not inhibit the catalytic activity of AChE that we exploit through immobilization of the DNA on a streptavidin-coated surface. Subsequent immobilization of AChE by the aptamer results in a 4-fold higher catalytic activity when compared to adsorption directly on to plastic.

  3. High-Throughput Genomics Enhances Tomato Breeding Efficiency (United States)

    Barone, A; Di Matteo, A; Carputo, D; Frusciante, L


    Tomato (Solanum lycopersicum) is considered a model plant species for a group of economically important crops, such as potato, pepper, eggplant, since it exhibits a reduced genomic size (950 Mb), a short generation time, and routine transformation technologies. Moreover, it shares with the other Solanaceous plants the same haploid chromosome number and a high level of conserved genomic organization. Finally, many genomic and genetic resources are actually available for tomato, and the sequencing of its genome is in progress. These features make tomato an ideal species for theoretical studies and practical applications in the genomics field. The present review describes how structural genomics assist the selection of new varieties resistant to pathogens that cause damage to this crop. Many molecular markers highly linked to resistance genes and cloned resistance genes are available and could be used for a high-throughput screening of multiresistant varieties. Moreover, a new genomics-assisted breeding approach for improving fruit quality is presented and discussed. It relies on the identification of genetic mechanisms controlling the trait of interest through functional genomics tools. Following this approach, polymorphisms in major gene sequences responsible for variability in the expression of the trait under study are then exploited for tracking simultaneously favourable allele combinations in breeding programs using high-throughput genomic technologies. This aims at pyramiding in the genetic background of commercial cultivars alleles that increase their performances. In conclusion, tomato breeding strategies supported by advanced technologies are expected to target increased productivity and lower costs of improved genotypes even for complex traits. PMID:19721805

  4. An Efficient, Highly Flexible Multi-Channel Digital Downconverter Architecture (United States)

    Goodhart, Charles E.; Soriano, Melissa A.; Navarro, Robert; Trinh, Joseph T.; Sigman, Elliott H.


    In this innovation, a digital downconverter has been created that produces a large (16 or greater) number of output channels of smaller bandwidths. Additionally, this design has the flexibility to tune each channel independently to anywhere in the input bandwidth to cover a wide range of output bandwidths (from 32 MHz down to 1 kHz). Both the flexibility in channel frequency selection and the more than four orders of magnitude range in output bandwidths (decimation rates from 32 to 640,000) presented significant challenges to be solved. The solution involved breaking the digital downconversion process into a two-stage process. The first stage is a 2 oversampled filter bank that divides the whole input bandwidth as a real input signal into seven overlapping, contiguous channels represented with complex samples. Using the symmetry of the sine and cosine functions in a similar way to that of an FFT (fast Fourier transform), this downconversion is very efficient and gives seven channels fixed in frequency. An arbitrary number of smaller bandwidth channels can be formed from second-stage downconverters placed after the first stage of downconversion. Because of the overlapping of the first stage, there is no gap in coverage of the entire input bandwidth. The input to any of the second-stage downconverting channels has a multiplexer that chooses one of the seven wideband channels from the first stage. These second-stage downconverters take up fewer resources because they operate at lower bandwidths than doing the entire downconversion process from the input bandwidth for each independent channel. These second-stage downconverters are each independent with fine frequency control tuning, providing extreme flexibility in positioning the center frequency of a downconverted channel. Finally, these second-stage downconverters have flexible decimation factors over four orders of magnitude The algorithm was developed to run in an FPGA (field programmable gate array) at input data

  5. Highly efficient tandem polymer solar cells with a photovoltaic response in the visible light range. (United States)

    Zheng, Zhong; Zhang, Shaoqing; Zhang, Maojie; Zhao, Kang; Ye, Long; Chen, Yu; Yang, Bei; Hou, Jianhui


    Highly efficient polymer solar cells with a tandem structure are fabricated by using two excellent photovoltaic polymers and a highly transparent intermediate recombination layer. Power conversion -efficiencies over 10% can be realized with a photovoltaic response within 800 nm. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. Microdischarge Array Flexible Light Source for High-Efficiency Irradiation of Spaced-Based Crops Project (United States)

    National Aeronautics and Space Administration — It is desirable to develop a high-efficiency lighting source for large-area irradiation of space-based crops. The key requirements for such a system include high...

  7. HIgh Efficiency Laser for Aircraft/UAV and Space Lidar Missions Project (United States)

    National Aeronautics and Space Administration — This SBIR is developing high-efficiency, high beam-quality Nd lasers and non-linear wavelength conversion technologies suitable for ozone, aerosol, oxygen, CO2,...

  8. MMIC for High-Efficiency Ka-BAnd GaN Power Amplifiers (2007043) Project (United States)

    National Aeronautics and Space Administration — This proposal addresses the need for high-efficiency, high-output power amplifiers operating in the Ka-band frequencies. For space communications, the power...

  9. High-efficiency resonantly pumped 1550-nm fiber-based laser transmitter Project (United States)

    National Aeronautics and Space Administration — nLight proposes the development of high efficiency, high average power 1550-nm laser transmitter system that is based on Er-doped fiber amplifier resonantly pumped...

  10. HIgh Efficiency Laser for Aircraft/UAV and Space Lidar Missions Project (United States)

    National Aeronautics and Space Administration — This SBIR will develop advanced, high-efficiency, high beam-quality solid-state laser technology and non-linear wavelength conversion technology suitable for Ozone,...

  11. Reverse energy-pooling collisions: K(5D)+Na(3S){r_arrow}K(4P)+Na(3P)

    Energy Technology Data Exchange (ETDEWEB)

    Guldberg-Kjaer, S.; De Filippo, G.; Milosevic, S.; Magnier, S.; Pedersen, J.O. [Niels Bohr Institute, O/rsted Laboratory, Universitetsparken 5, DK-2100, Copenhagen O/ (Denmark); Allegrini, M. [Unita INFM, Dipartimento di Fisica, Universita di Pisa, Piazza Torricelli 2, I--56126, Pisa (Italy)


    The observation of a heteronuclear reverse energy pooling process is reported. The cross section for the collision processes K(5D)+Na(3S){r_arrow}K(4P)+Na(3P) has been measured and compared to calculations carried out using a multicrossing Landau-Zener model. {copyright} {ital 1997} {ital The American Physical Society}

  12. Direct observation of pure one-electron capture from the target inner shell in low-energy p+Na collisions

    NARCIS (Netherlands)

    Knoop, S; Morgenstern, R; Hoekstra, R


    One-electron removal in the p+Na collision system has been investigated at low energy (4-25 keV) by means of recoil ion momentum spectroscopy. The focus will be on the contribution of one-electron capture from the Na 2p inner shell into the hydrogen ground state, thereby leaving the Na+ target ion

  13. Morphology Engineering: A Route to Highly Reproducible and High Efficiency Perovskite Solar Cells. (United States)

    Bi, Dongqin; Luo, Jingshan; Zhang, Fei; Magrez, Arnaud; Athanasopoulou, Evangelia Nefeli; Hagfeldt, Anders; Grätzel, Michael


    Despite the rapid increase in the performance of perovskite solar cells (PSC), they still suffer from low lab-to-lab or people-to-people reproducibility. Aiming for a universal condition to high-performance devices, we investigated the morphology evolution of a composite perovskite by tuning annealing temperature and precursor concentration of the perovskite film. Here, we introduce thermal annealing as a powerful tool to generate a well-controlled excess of PbI2 in the perovskite formulation and show that this benefits the photovoltaic performance. We demonstrated the correlation between the film microstructure and electronic property and device performance. An optimized average grain size/thickness aspect ratio of the perovskite crystallite is identified, which brings about a highly reproducible power conversion efficiency (PCE) of 19.5 %, with a certified value of 19.08 %. Negligible hysteresis and outstanding morphology stability are observed with these devices. These findings lay the foundation for further boosting the PCE of PSC and can be very instructive for fabrication of high-quality perovskite films for a variety of applications, such as light-emitting diodes, field-effect transistors, and photodetectors. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. Highly efficient and durable TiN nanofiber electrocatalyst supports (United States)

    Kim, Hyun; Cho, Min Kyung; Kwon, Jeong An; Jeong, Yeon Hun; Lee, Kyung Jin; Kim, Na Young; Kim, Min Jung; Yoo, Sung Jong; Jang, Jong Hyun; Kim, Hyoung-Juhn; Nam, Suk Woo; Lim, Dong-Hee; Cho, Eunae; Lee, Kwan-Young; Kim, Jin Young


    To date, carbon-based materials including various carbon nanostructured materials have been extensively used as an electrocatalyst support for proton exchange membrane fuel cell (PEMFC) applications due to their practical nature. However, carbon dissolution or corrosion caused by high electrode potential in the presence of O2 and/or water has been identified as one of the main failure modes for the device operation. Here, we report the first TiN nanofiber (TNF)-based nonwoven structured materials to be constructed via electrospinning and subsequent two-step thermal treatment processes as a support for the PEMFC catalyst. Pt catalyst nanoparticles (NPs) deposited on the TNFs (Pt/TNFs) were electrochemically characterized with respect to oxygen reduction reaction (ORR) activity and durability in an acidic medium. From the electrochemical tests, the TNF-supported Pt catalyst was better and more stable in terms of its catalytic performance compared to a commercially available carbon-supported Pt catalyst. For example, the initial oxygen reduction performance was comparable for both cases, while the Pt/TNF showed much higher durability from an accelerated degradation test (ADT) configuration. It is understood that the improved catalytic roles of TNFs on the supported Pt NPs for ORR are due to the high electrical conductivity arising from the extended connectivity, high inertness to the electrochemical environment and strong catalyst-support interactions.To date, carbon-based materials including various carbon nanostructured materials have been extensively used as an electrocatalyst support for proton exchange membrane fuel cell (PEMFC) applications due to their practical nature. However, carbon dissolution or corrosion caused by high electrode potential in the presence of O2 and/or water has been identified as one of the main failure modes for the device operation. Here, we report the first TiN nanofiber (TNF)-based nonwoven structured materials to be constructed via

  15. High-Tech Means High-Efficiency: The Business Case for EnergyManagement in High-Tech Industries

    Energy Technology Data Exchange (ETDEWEB)

    Shanshoian, Gary; Blazek, Michele; Naughton, Phil; Seese, RobertS.; Mills, Evan; Tschudi, William


    In the race to apply new technologies in ''high-tech'' facilities such as data centers, laboratories, and clean rooms, much emphasis has been placed on improving service, building capacity, and increasing speed. These facilities are socially and economically important, as part of the critical infrastructure for pharmaceuticals,electronics, communications, and many other sectors. With a singular focus on throughput, some important design issues can be overlooked, such as the energy efficiency of individual equipment (e.g., lasers, routers and switches) as well as the integration of high-tech equipment into the power distribution system and the building envelope. Among technology-based businesses, improving energy efficiency presents an often untapped opportunity to increase profits, enhance process control,maximize asset value, improve the work place environment, and manage a variety of business risks. Oddly enough, the adoption of energy efficiency improvements in this sector lags behind many others. As a result, millions of dollars are left on the table with each year ofoperation.

  16. Development of High Efficiency Swing Compressor for R32 Refrigerant


    Yamamoto, Yuuichi; Kanayama, Takehiro; Yuasa, Kenichi; Matsuura, Hideki


    In the age of global warming, energy saving features and overall reduction of environmental impact are critical components that must be addressed when developing new HVAC units. We chose the R32 refrigerant, with its lower LCCP as a more sustainable choice than the R410A. However, R32 has its drawbacks. Due to its smaller molecular weight, internal leakage loss is higher for the R32. Moreover, high discharge gas temperature decrease the reliability of the compressor, and make a large overheat...

  17. High Efficiency Boost Converter with Three State Switching Cell

    DEFF Research Database (Denmark)

    Klimczak, Pawel; Munk-Nielsen, Stig


    The boost converter with the three-state switching cell seems to be a good candidate for a dc-dc stage for non-isolated generators based on alternative energy sources. It provides a high voltage gain, a reduced voltage stress on transistors and limited input current ripples. In this paper the focus...... is on performance improvement of this type of the converter. Use of foil windings helps to reduce conduction losses in magnetic components and to reduce size of these components. Also it has been demonstrated that the regulation range of this type of converter can be increased by operation with duty cycle lower...

  18. Ultra-high Efficiency DC-DC Converter using GaN Devices

    DEFF Research Database (Denmark)

    Ramachandran, Rakesh


    with the PCB layout and the magnetics. This thesis mainly covers the design and implementation of various high efficiency isolated dcdc converters in the range of 1 to 2.5 kW of output power. Both hard-switched and soft-switched topologies in isolated dc-dc converters has been studied and realized......The demands for high efficiency dc-dc power converters are increasing day by day in various applications such as telecommunication, data-centers, electric vehicles and various renewable energy systems. Silicon (Si) has been used as the semiconductor material in majority of the power devices...... properties of GaN devices can be utilized in power converters to make them more compact and highly efficient. This thesis entitled “Ultra-high Efficiency DC-DC Converter using GaN devices” focuses on achieving ultra-high conversion efficiency in an isolated dc-dc converter by the optimal utilization of Ga...

  19. Highly-efficient noise-assisted energy transport in classical oscillator systems

    CERN Document Server

    León-Montiel, R de J


    Photosynthesis is a biological process that involves the highly-efficient transport of energy captured from the sun to a reaction center, where conversion into useful biochemical energy takes place. Even though one can always use a quantum perspective to describe any physical process, since everything follows the laws of Quantum Mechanics, is the use of quantum theory imperative to explain this high efficiency? Several theoretical studies suggest that the high efficiency can only be understood as a result of the interplay between the quantum coherent evolution of the photosynthetic system, and noise introduced by its surrounding environment. Notwithstanding, we show here that noise-assisted highly-efficient energy transport can be found as well in purely classical systems; therefore, we might conclude that high efficiency energy transfer in photosynthetic systems could also be anticipated by classical models, without the need to resorting to quantum effects. Strikingly, the wider scope of applicability of the...

  20. Development of highly efficient solid oxide electrolyzer cell systems

    DEFF Research Database (Denmark)

    Duhn, Jakob Dragsbæk

    , when SOECs are used in systems like Haldor Topsoe A/S’s “eCOs”. In this way, the overall eÿciency of SOEC systems are increased. The CO concentration was limited by carbon formation via the Boudouard reaction, a non-uniform flow in the fuel channels over the fuel electrode, and the di˙usion in the fuel...... with flow rate and therefore high CO concentration. The flow distribution in the fuel channels over the fuel electrode was investigated with computational fluid dynamics (CFD) modeling. The flow was optimized by changing the cell inlet geometry and an increase in the flow uniformity was observed. The impact...... on the allowed average (exit) CO concentration was quite high (from 22 to 32 %). The effective diffusion in the fuel electrode was investigated with a Wicke-Kallenbach set up. Combined with measurements of the thickness, porosity and pore size, the tortuosity of the material was calculated. This made it possible...

  1. Efficient Management of High-Throughput Screening Libraries with SAVANAH. (United States)

    List, Markus; Elnegaard, Marlene Pedersen; Schmidt, Steffen; Christiansen, Helle; Tan, Qihua; Mollenhauer, Jan; Baumbach, Jan


    High-throughput screening (HTS) has become an indispensable tool for the pharmaceutical industry and for biomedical research. A high degree of automation allows for experiments in the range of a few hundred up to several hundred thousand to be performed in close succession. The basis for such screens are molecular libraries, that is, microtiter plates with solubilized reagents such as siRNAs, shRNAs, miRNA inhibitors or mimics, and sgRNAs, or small compounds, that is, drugs. These reagents are typically condensed to provide enough material for covering several screens. Library plates thus need to be serially diluted before they can be used as assay plates. This process, however, leads to an explosion in the number of plates and samples to be tracked. Here, we present SAVANAH, the first tool to effectively manage molecular screening libraries across dilution series. It conveniently links (connects) sample information from the library to experimental results from the assay plates. All results can be exported to the R statistical environment or piped into HiTSeekR ( ) for comprehensive follow-up analyses. In summary, SAVANAH supports the HTS community in managing and analyzing HTS experiments with an emphasis on serially diluted molecular libraries.

  2. High-Density Nanosharp Microstructures Enable Efficient CO2 Electroreduction. (United States)

    Saberi Safaei, Tina; Mepham, Adam; Zheng, Xueli; Pang, Yuanjie; Dinh, Cao-Thang; Liu, Min; Sinton, David; Kelley, Shana O; Sargent, Edward H


    Conversion of CO2 to CO powered by renewable electricity not only reduces CO2 pollution but also is a means to store renewable energy via chemical production of fuels from CO. However, the kinetics of this reaction are slow due its large energetic barrier. We have recently reported CO2 reduction that is considerably enhanced via local electric field concentration at the tips of sharp gold nanostructures. The high local electric field enhances CO2 concentration at the catalytic active sites, lowering the activation barrier. Here we engineer the nucleation and growth of next-generation Au nanostructures. The electroplating overpotential was manipulated to generate an appreciably increased density of honed nanoneedles. Using this approach, we report the first application of sequential electrodeposition to increase the density of sharp tips in CO2 electroreduction. Selective regions of the primary nanoneedles are passivated using a thiol SAM (self-assembled monolayer), and then growth is concentrated atop the uncovered high-energy planes, providing new nucleation sites that ultimately lead to an increase in the density of the nanosharp structures. The two-step process leads to a new record in CO2 to CO reduction, with a geometric current density of 38 mA/cm2 at -0.4 V (vs reversible hydrogen electrode), and a 15-fold improvement over the best prior reports of electrochemical surface area (ECSA) normalized current density.

  3. Second Generation Advanced Reburning for High Efficiency NOx Control

    Energy Technology Data Exchange (ETDEWEB)

    Vladimir M. Zamansky; Peter M. Maly; Vitali V. Lissianski; Mark S. Sheldon; David Moyeda; Roy Payne


    viability of the AR technology. The performance goals of the project to reduce NO{sub x} by up to 95% with net emissions less than 0.06 lb/10{sup 6} Btu and to minimize other pollutants (N{sub 2}O and NH{sub 3}) to levels lower than reburning and SNCR have been met. Experimental data demonstrated that AR-Lean + SNCR and Reburning + SNCR are the most effective AR configurations, followed by AR-Lean and AR-Rich. Promoters can increase AR NO{sub x} reduction efficiency. Promoters are the most effective at small amounts of the reburning fuel (6-10% of the total fuel heat input). Promoters provide the means to improve NO{sub x} reduction and simultaneously decrease the amount of reburning fuel. Tests also showed that alkali-containing compounds are effective promoters of the AR process. When co-injected with N-agent, they provide up to 25 % improvement in NO{sub x} reduction. A detailed reaction mechanism and simplified representation of mixing were used in modeling of AR processes. Modeling results demonstrated that the model correctly described a wide range of experimental data. Mixing and thermal parameters in the model can be adjusted depending on characteristics of the combustion facility. Application of the model to the optimization of AR-Lean has been demonstrated. Economic analysis demonstrated a considerable economic advantage of AR technologies in comparison with existing commercial NO{sub x} control techniques, such as basic reburning, SNCR, and SCR. Particularly for deep NO{sub x} control, coal-based AR technologies are 50% less expansive than SCR for the same level of NO{sub x} control. The market for AR technologies is estimated to be above $110 million.

  4. Highly efficient proteolysis accelerated by electromagnetic waves for Peptide mapping. (United States)

    Chen, Qiwen; Liu, Ting; Chen, Gang


    Proteomics will contribute greatly to the understanding of gene functions in the post-genomic era. In proteome research, protein digestion is a key procedure prior to mass spectrometry identification. During the past decade, a variety of electromagnetic waves have been employed to accelerate proteolysis. This review focuses on the recent advances and the key strategies of these novel proteolysis approaches for digesting and identifying proteins. The subjects covered include microwave-accelerated protein digestion, infrared-assisted proteolysis, ultraviolet-enhanced protein digestion, laser-assisted proteolysis, and future prospects. It is expected that these novel proteolysis strategies accelerated by various electromagnetic waves will become powerful tools in proteome research and will find wide applications in high throughput protein digestion and identification.

  5. Efficient polarization of high-angular-momentum systems

    CERN Document Server

    Rochester, Simon; Raizen, Mark; Pustelny, Szymon; Auzinsh, Marcis; Budker, Dmitry


    We propose methods of optical pumping that are applicable to open, high-angular-momentum transitions in atoms and molecules, for which conventional optical pumping would lead to significant population loss. Instead of applying circularly polarized cw light, as in conventional optical pumping, we propose to use techniques for coherent population transfer (e.g., adiabatic fast passage) to arrange the atoms so as to increase the entropy removed from the system with each spontaneous decay from the upper state. This minimizes the number of spontaneous-emission events required to produce a stretched state, thus reducing the population loss due to decay to other states. To produce a stretched state in a manifold with angular momentum J, conventional optical pumping requires about 2J spontaneous decays per atom; one of our proposed methods reduces this to about log_2(2J), while another of the methods reduces it to about one spontaneous decay, independent of J.

  6. Development of high efficiency collector plates. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Santala, T.; Sabol, R.


    Composite metal technology was used to manufacture intermetallic compound (IC) absorption surfaces and to combine them integrally with composite metal tube-in-sheet collector plates. Five material systems in which Al was one component metal and Fe, Cr, or Ni and their alloy was the other pair, were evaluated. All intermetallic compounds had high solar absorptance ..cap alpha.. approx. = 0.9. The AlNi was most promising and ..cap alpha.. > or = 0.95 and epsilon approx. = 0.3 were obtained over a broad range of compounding conditions. After eight months exposure in a flat plate collector enclosure the characteristic properties of AlNi surfaces remained virtually unchanged. Only LCS/Cu composite metal tube-in-sheet collector plates could be manufactured successfully. The technical difficulties associated with integrating the intermetallic compound and tube-in-sheet technologies make the manufacturing of composite metal collector plates at the time being economically unfeasible.

  7. High efficiency cell-specific targeting of cytokine activity (United States)

    Garcin, Geneviève; Paul, Franciane; Staufenbiel, Markus; Bordat, Yann; van der Heyden, José; Wilmes, Stephan; Cartron, Guillaume; Apparailly, Florence; de Koker, Stefaan; Piehler, Jacob; Tavernier, Jan; Uzé, Gilles


    Systemic toxicity currently prevents exploiting the huge potential of many cytokines for medical applications. Here we present a novel strategy to engineer immunocytokines with very high targeting efficacies. The method lies in the use of mutants of toxic cytokines that markedly reduce their receptor-binding affinities, and that are thus rendered essentially inactive. Upon fusion to nanobodies specifically binding to marker proteins, activity of these cytokines is selectively restored for cell populations expressing this marker. This ‘activity-by-targeting’ concept was validated for type I interferons and leptin. In the case of interferon, activity can be directed to target cells in vitro and to selected cell populations in mice, with up to 1,000-fold increased specific activity. This targeting strategy holds promise to revitalize the clinical potential of many cytokines.

  8. Efficient dual layer interconnect coating for high temperature electrochemical devices

    DEFF Research Database (Denmark)

    Palcut, Marián; Mikkelsen, Lars; Neufeld, Kai


    that the oxidation reaction is limited by outward Cr3+ diffusion in the chromia scale. The coating effectively reduces the oxidation rate. Reactions and cation inter-diffusion between the coating and the oxide scale are observed. Long term effects of these interactions are discussed and practical implications......Effects of novel dual layer coatings Co3O4/La0.85Sr0.15MnO3−δ on high temperature oxidation behaviour of candidate steels for interconnects are studied at 1123 K in flowing simulated ambient air (air + 1% H2O) and oxygen. Four alloys are investigated: Crofer 22 APU, Crofer 22 H, E-Brite and AL 29......-4C. The reaction kinetics is followed by measuring the mass increase of the samples over time. The oxide scale microstructure and chemical composition are investigated by scanning electron microscopy/energy dispersive spectroscopy. The kinetic data follow the parabolic rate law. It is found...

  9. A high efficient method for demodulation of FBG sensors (United States)

    Ni, Yi; Qin, Xuanyi; Yao, Huixuan; Guo, Yu; Chen, Xiangfei


    In this paper, a strain sensing system based on Distributed-Feedback (DFB) laser array and a high effective demodulate algorithm is proposed. The uniqueness and innovation of the algorithm is in the following two aspects: one is that accurate demodulation can be achieved by scanning only 0.4 nm bandwidth of fiber Bragg grating (FBG) spectrum instead of relying on scanning FBG's principal power peak; and the other is that the scanned spectrum can be any part of reflected spectrum of FBG sensor, which make it possible of using wavelength-division multiplexing (WDM) for FBG sensing network. In the experiment, DFB laser array with single-channel and four-channel are used to demonstrate the proposed algorithm. Experiments results show that the single-channel's error is below 5 pm, four-channel's is below 2 pm, strain and algorithm results show good linearity.

  10. A Experimental and Theoretical Study of High - High-Efficiency Sirens. (United States)

    Pla, Frederic Ghislain

    High-intensity, high-efficiency sound sources are needed for acoustic agglomeration of particle-laden aerosols in power plant flues and for combustion enhancement. The theory of the linear model is reviewed and shown to be in strong disagreement with experimental results. The experimental evaluation of sirens is then discussed. It is shown that high sound pressure levels strongly affect the evaluation of the performance of high-intensity sound sources. The mechanical design of an experimental and a full-size siren is presented. Tunable inlet chambers are included to minimize the acoustic power radiated backward in the siren. The experimental results show that tunable inlets are most effective at low pressure ratios and low frequencies. The main acoustic losses are due to the sound radiated backward into the siren chamber, the acoustic boundary-layer, the clearance between rotor and stator, and the finite-amplitude character of the acoustic wave. A theoretical study of the sound generation mechanism in sirens is then presented. The various sound attenuation mechanisms are reviewed and a low frequency numerical solution for the frequency response is given which includes arbitrary attenuation, dispersion, horn shape, and mean flow. Next finite-amplitude sound propagation in a horn is studied. Results are presented that agree very well with experimental data. Important nonlinear phenomena such as shock formation, acoustic saturation, and distortion of initially non-sinusoidal finite-amplitude waves are discussed. Finally, a new siren design methodology is presented, including a step-by-step discussion on how to minimize the acoustic losses.

  11. Efficient Extraction of High Centrality Vertices in Distributed Graphs

    Energy Technology Data Exchange (ETDEWEB)

    Kumbhare, Alok [Univ. of Southern California, Los Angeles, CA (United States); Frincu, Marc [Univ. of Southern California, Los Angeles, CA (United States); Raghavendra, Cauligi S. [Univ. of Southern California, Los Angeles, CA (United States); Prasanna, Viktor K. [Univ. of Southern California, Los Angeles, CA (United States)


    Betweenness centrality (BC) is an important measure for identifying high value or critical vertices in graphs, in variety of domains such as communication networks, road networks, and social graphs. However, calculating betweenness values is prohibitively expensive and, more often, domain experts are interested only in the vertices with the highest centrality values. In this paper, we first propose a partition-centric algorithm (MS-BC) to calculate BC for a large distributed graph that optimizes resource utilization and improves overall performance. Further, we extend the notion of approximate BC by pruning the graph and removing a subset of edges and vertices that contribute the least to the betweenness values of other vertices (MSL-BC), which further improves the runtime performance. We evaluate the proposed algorithms using a mix of real-world and synthetic graphs on an HPC cluster and analyze its strengths and weaknesses. The experimental results show an improvement in performance of upto 12x for large sparse graphs as compared to the state-of-the-art, and at the same time highlights the need for better partitioning methods to enable a balanced workload across partitions for unbalanced graphs such as small-world or power-law graphs.

  12. Efficiency of liquid-jet high-pressure booster compressors (United States)

    Mikheev, N. I.; Davletshin, I. A.; Mikheev, A. N.; Kratirov, D. V.; Fafurin, V. A.


    There are almost no experimental data on the head-capacity curves for liquid-jet compressors with the inlet gas pressure of liquid-jet apparatus more than 1 MPa. Meanwhile, this range is important for many engineering applications in which relatively low compressor ratio is required for the pumping of gas under high pressure. This is mostly the case when gas circulation is to be provided in a closed or almost closed circuit. A head-capacity curve of a liquid-jet apparatus has been estimated experimentally for the air pumping at up to 2.5 MPa by a water jet. To obtain this curve, a new original technique has been submitted and verified which is based on an inverse unsteady problem of gas pumping and allows derivation of the whole curve instead of one operating point, which is the case for conventional methods. The experiments have demonstrated that the relative head of the liquid-jet compressor grows with the apparatus inlet air pressure in the middle part of the curve.

  13. Cell Penetration Properties of a Highly Efficient Mini Maurocalcine Peptide

    Directory of Open Access Journals (Sweden)

    Michel De Waard


    Full Text Available Maurocalcine is a highly potent cell-penetrating peptide isolated from the Tunisian scorpion Maurus palmatus. Many cell-penetrating peptide analogues have been derived from the full-length maurocalcine by internal cysteine substitutions and sequence truncation. Herein we have further characterized the cell-penetrating properties of one such peptide, MCaUF1-9, whose sequence matches that of the hydrophobic face of maurocalcine. This peptide shows very favorable cell-penetration efficacy compared to Tat, penetratin or polyarginine. The peptide appears so specialized in cell penetration that it seems hard to improve by site directed mutagenesis. A comparative analysis of the efficacies of similar peptides isolated from other toxin members of the same family leads to the identification of hadrucalcin’s hydrophobic face as an even better CPP. Protonation of the histidine residue at position 6 renders the cell penetration of MCaUF1-9 pH-sensitive. Greater cell penetration at acidic pH suggests that MCaUF1-9 can be used to specifically target cancer cells in vivo where tumor masses grow in more acidic environments.

  14. New approaches for high-efficiency solar cells. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Bedair, S M; El-Masry, N A [North Carolina State Univ., Raleigh, NC (United States)


    This report summarizes the activities carried out in this subcontract. These activities cover, first the atomic layer epitaxy (ALE) growth of GaAs, AlGaAs and InGaP at fairly low growth temperatures. This was followed by using ALE to achieve high levels of doping both n-type and p-type required for tunnel junctions (Tj) in the cascade solar cell structures. Then the authors studied the properties of AlGaAs/InGaP and AlGaAs/GaAs tunnel junctions and their performances at different growth conditions. This is followed by the use of these tunnel junctions in stacked solar cell structures. The effect of these tunnel junctions on the performance of stacked solar cells was studied at different temperatures and different solar fluences. Finally, the authors studied the effect of different types of black surface fields (BSF), both p/n and n/p GaInP solar cell structures, and their potential for window layer applications. Parts of these activities were carried in close cooperation with Dr. Mike Timmons of the Research Triangle Institute.

  15. Cell Penetration Properties of a Highly Efficient Mini Maurocalcine Peptide (United States)

    Tisseyre, Céline; Bahembera, Eloi; Dardevet, Lucie; Sabatier, Jean-Marc; Ronjat, Michel; De Waard, Michel


    Maurocalcine is a highly potent cell-penetrating peptide isolated from the Tunisian scorpion Maurus palmatus. Many cell-penetrating peptide analogues have been derived from the full-length maurocalcine by internal cysteine substitutions and sequence truncation. Herein we have further characterized the cell-penetrating properties of one such peptide, MCaUF1-9, whose sequence matches that of the hydrophobic face of maurocalcine. This peptide shows very favorable cell-penetration efficacy compared to Tat, penetratin or polyarginine. The peptide appears so specialized in cell penetration that it seems hard to improve by site directed mutagenesis. A comparative analysis of the efficacies of similar peptides isolated from other toxin members of the same family leads to the identification of hadrucalcin’s hydrophobic face as an even better CPP. Protonation of the histidine residue at position 6 renders the cell penetration of MCaUF1-9 pH-sensitive. Greater cell penetration at acidic pH suggests that MCaUF1-9 can be used to specifically target cancer cells in vivo where tumor masses grow in more acidic environments. PMID:24276021

  16. A high-efficiency indirect lighting system utilizing the solar 1000 sulfur lamp

    Energy Technology Data Exchange (ETDEWEB)

    Siminovitch, M.; Gould, C.; Page, E.


    High-lumen light sources represent unique challenges and opportunities for the design of practical and efficient interior lighting systems. High-output sources require a means of large-scale distribution and avoidance of high-luminance glare while providing efficient delivery. An indirect lighting system has been developed for use with a 1,000 Watt sulfur lamp that efficiently utilizes the high-output source to provide quality interior lighting. This paper briefly describes the design and initial testing of this new system.

  17. A new design for a high resolution, high efficiency CZT gamma camera detector (United States)

    Mestais, C.; Baffert, N.; Bonnefoy, J. P.; Chapuis, A.; Koenig, A.; Monnet, O.; Ouvrier Buffet, P.; Rostaing, J. P.; Sauvage, F.; Verger, L.


    We have designed a CZT gamma camera detector that provides an array of CZT pixels and associated front-end electronics - including an ASIC - and permits gamma camera measurements using the method patented by CEA-LETI and reported by Verger et al. [1]. Electron response in each CZT pixel is registered by correcting pulse height for position of interaction based on fast rise-time information. This method brings advantages of high scatter rejection while allowing high detection efficiency. These techniques and the systems approach have been developed at CEA-LETI in an exclusive joint development with BICRON and CRISMATEC who in turn are commercializing the technology. The initial system is implemented in an array framework with 1920 pixels, approximately 180×215 mm 2 in dimension, but the system architecture expands readily to 4096 pixels, and these arrays can be ganged into groups of up to 8 for pixel planes totaling over 32 000 pixels without architecture changes. The overall system design is described and brain phantom images are presented that were obtained by scanning with a small number of pixels.

  18. Stellar velocimetry with a novel high efficiency interferometer

    Energy Technology Data Exchange (ETDEWEB)

    Erskine, D J; Ge, J


    The search for extra-solar planets continues to be one of the most exciting fields in astronomy, with great interest shown by the public. The detection of planets via the Doppler effect, measuring the gravitational tugging of the planet on the parent star, is the most popular method. Jupiter and Saturn-like planets create 12 and 3 m/s signatures, respectively. Many institutions endeavor to join the search. They are hampered by the lack of affordable instruments having sufficient velocity resolution. Conventional high spectral resolution grating spectrometers are extremely expensive and massive due to their large size (5 meters). Due to their extreme sensitivity to input beam path, the most accurate velocimeters must use the iodine vapor cell as a spectral reference, (which does not deviate the beam due to its absorptive nature.) However, this operates only with green light. Hence, most of the photons from a star are wasted, particularly from red stars. In spite of constituting more than 60% of stars near Earth, red stars are currently under-represented on planet search surveys due to their relative weakness in the green. We have developed a new method for measuring Doppler shifts of starlight having many practical benefits. It is based on the combination of an interferometer with a small, low resolution diffraction grating. Since the Doppler effect is measured by fringe shifts, and not directly by the grating, the required grating spectral resolution can be reduced by a factor of 3 to 10 times. Secondly, the tolerance to imperfections in the grating is much higher. These properties allow the overall instrument to be dramatically smaller (TV-sized vs. kitchen sized), inexpensive and portable. Airborne and spaceborne platforms are now possible for the first time. Furthermore, the interferometer is 1000 times less sensitive to errors in the beam path. This enables use of an emission lamp as a spectral reference, which would allow the velocimeter to use all the colors

  19. Highly efficient and compatible shampoo for use after hair transplant. (United States)

    Schweiger, Dorothea; Schoelermann, Andrea M; Filbry, Alexander; Hamann, Tina; Moser, Claudia; Rippke, Frank


    Sensitive or hyperreactive skin is a common condition defined by prickling, burning, pain, and pruritus. Although this skin problem was initially described on the face, the scalp is often affected. A sensitive scalp can react with irritation to harsh surfactants or other additives which are often present in shampoos. For this reason, we developed a new rinse-off hypertolerant shampoo specifically designed for the hypersensitive and problematic scalp. The shampoo formulation is based on an extremely mild surfactant system and contains bisabolol, an anti-irritant and anti-inflammatory ingredient of chamomile. The shampoo is free of additives such as perfumes, silicones, colorants, parabens, paraffins, and betaine. Since skin can remain in a hyperreactive state after wounding, the status after hair transplantation was chosen as a model system to test the shampoo. Scalp condition and compatibility of each volunteer were analyzed by a plastic surgeon directly after hair transplant and after stitch removal. The plastic surgeons also rated whether they would recommend the further use of the test shampoo. Additionally, volunteers completed a self-assessment questionnaire. Following hair transplantation, regular use of the shampoo resulted in a significant reduction in the extent of scabbing and erythema. This was confirmed by dermatological scalp examinations performed by the plastic surgeon as well as in volunteers' self-assessments. The plastic surgeon highly recommended the further use of the test shampoo after hair transplant to all study participants. Application of the test shampoo demonstrated excellent skin compatibility and product efficacy after hair transplant. The test shampoo significantly reduced the extent of scabs and erythema. Therefore, the shampoo is ideally suited for use after hair transplantation and for the treatment of sensitive scalp. The excellent skin compatibility is because of the mild surfactant system, the calming ingredient bisabolol, and

  20. New III-V cell design approaches for very high efficiency

    Energy Technology Data Exchange (ETDEWEB)

    Lundstrom, M.S.; Melloch, M.R.; Lush, G.B.; Patkar, M.P.; Young, M.P. (Purdue Univ., Lafayette, IN (United States))


    This report describes to examine new solar cell desip approaches for achieving very high conversion efficiencies. The program consists of two elements. The first centers on exploring new thin-film approaches specifically designed for M-III semiconductors. Substantial efficiency gains may be possible by employing light trapping techniques to confine the incident photons, as well as the photons emitted by radiative recombination. The thin-film approach is a promising route for achieving substantial performance improvements in the already high-efficiency, single-junction, III-V cell. The second element of the research involves exploring desip approaches for achieving high conversion efficiencies without requiring extremely high-quality material. This work has applications to multiple-junction cells, for which the selection of a component cell often involves a compromise between optimum band pp and optimum material quality. It could also be a benefit manufacturing environment by making the cell's efficiency less dependent on materialquality.