WorldWideScience

Sample records for higher mass values

  1. Higher Education and Ethical Value

    Science.gov (United States)

    Lee, Jeong-Kyu

    2017-01-01

    The purpose of this study is to explore the importance of ethical value in higher education as well as the relevance between ethical value and higher education. In order to examine the study logically, three research questions are addressed: First, what is value, ethical value, and Asiatic ethical value? Second, for whom and what is higher…

  2. Mass Notification for Higher Education

    Science.gov (United States)

    Schneider, Tod

    2010-01-01

    Mass notification is a high priority in educational institutions. As the number of electronic communication devices has diversified, so has the complexity of designing an effective mass notification system. Picking the right system, with the right features, support services and price, can be daunting. This publication, updated quarterly due to…

  3. Reconfiguring the Higher Education Value Chain

    Science.gov (United States)

    Pathak, Virendra; Pathak, Kavita

    2010-01-01

    Forces of demand and supply are changing the dynamics of the higher education market. Transformation of institutions of higher learning into competitive enterprise is underway. Higher education institutions are seemingly under intense pressure to create value and focus their efforts and scarce funds on activities that drive up value for their…

  4. Happiness and Ethical Values in Higher Education

    Science.gov (United States)

    Lee, Jeong-Kyu

    2017-01-01

    The purpose of this paper is to discuss relations between happiness and ethical values in higher education, focusing on the need for the university to pursue happiness and ethical values. To examine the paper logically, four research questions are addressed. First, what are general concepts of happiness and ethical values? Second, why higher…

  5. Higher education status in public value orientation

    Directory of Open Access Journals (Sweden)

    Olehnovica E.

    2012-10-01

    Full Text Available In the article the interrelationships between the types of dominating values in the society and corresponding consequences for higher education aims and objectives. In the context of the mentioned interrelationships, there are given the examples of studies offered by the USA and Daugavpils University, as well as the access to value structuring and typology found in scientific literature. The surveyed study results render the public evaluation on the instrumental and terminal values of the higher education. Authors pay a special attention to systemic view or four quadrant matrix use in the analysis of value formation process. Semantic analysis of the concept “knowledge” and hermeneutic interpretation depict the direct connection of the education with individual and collective values. By determining the values dominating in the public, one can predict its expectations in the field of education and adapt it to the necessary changes.

  6. Initial value formulation of higher derivative gravity

    International Nuclear Information System (INIS)

    Noakes, D.R.

    1983-01-01

    The initial value problem is considered for the conformally coupled scalar field and higher derivative gravity, by expressing the equations of each theory in harmonic coordinates. For each theory it is shown that the (vacuum) equations can take the form of a diagonal hyperbolic system with constraints on the initial data. Consequently these theories possess well-posed initial value formulations

  7. Geography and Values in Higher Education: 2

    Science.gov (United States)

    Huckle, John

    1978-01-01

    The geography curriculum in higher education reflects values held by the geographical and educational communities and by society in general. Teachers should transmit an environmental ethic by adopting relevant approaches from moral and political education. For journal availability, see SO 506 224. (Author/AV)

  8. Value Adding Space Management in Higher Education

    DEFF Research Database (Denmark)

    Tinsfeldt, Mette; Jensen, Per Anker

    2014-01-01

    Purpose : Develop a methodology for space optimisation in educational facilities, that can add value to organisations with particular focus on gymnasiums in Denmark. Background : Gymnasiums are pre-university higher educational institutions, which in 2007 went from being state-owned to being self...... evaluation of the combined use of POE and USEtool and represents an original contribution to the development of knowledge and methodology of value adding space management.......Purpose : Develop a methodology for space optimisation in educational facilities, that can add value to organisations with particular focus on gymnasiums in Denmark. Background : Gymnasiums are pre-university higher educational institutions, which in 2007 went from being state-owned to being self......-governing. Many older gymnasiums face the challenge that the institutions’ buildings and spaces are unsuitable to support modern teaching methods. A space optimisation process can help overcome some of these challenges as long as it makes use of a holistic analysis, is related to the strategic objectives...

  9. Mass and QEC value of 26Si

    International Nuclear Information System (INIS)

    Eronen, T.; Elomaa, V.-V.; Hager, U.; Hakala, J.; Jokinen, A.; Kankainen, A.; Kessler, T.; Moore, I. D.; Rahaman, S.; Rissanen, J.; Weber, C.; Aeystoe, J.

    2009-01-01

    The Q EC value of the superallowed β emitter 26 Si has been measured with the JYFLTRAP Penning trap facility to be 4840.85(10) keV which is ten times more precise than any previous measurement. This leaves only the branching ratio to be improved before the Ft value of 26 Si can be used to test the conserved vector current hypothesis. As a consequence, the 25 Al(p,γ) 26 Si reaction Q-value (Q pγ ) was improved to be 5513.7(5) keV, limited now by the mass excess of 25 Al. The new Q pγ value changes the stellar production rate of 26 Si in nova ignition temperatures by about 10%

  10. Pricing for Higher Education Institutions: A Value-Based Approach

    Science.gov (United States)

    Amir, Amizawati Mohd; Auzair, Sofiah Md; Maelah, Ruhanita; Ahmad, Azlina

    2016-01-01

    Purpose: The purpose of this paper is to propose the concept of higher education institutions (HEIs) offering educational services based on value for money. The value is determined based on customers' (i.e. students) expectations of the service and the costs in comparison to the competitors. Understanding the value and creating customer value are…

  11. Mass extrapolation of quarks and leptons to higher generations

    Energy Technology Data Exchange (ETDEWEB)

    Barik, N [Utkal Univ., Bhubaneswar (India). Dept. of Physics

    1981-05-01

    An empirical mass formula is tested for the basic fermion sequences of charged quarks and leptons. This relation is a generalization of Barut's mass formula for the lepton sequence (e, ..mu.., tau ....). It is found that successful mass extrapolation to the third and possibly to other higher generations (N > 2) can be obtained with the first and second generation masses as inputs, which predicts the top quark mass msub(t) to be around 20 GeV. This also leads to the mass ratios between members of two different sequences (i) and (i') corresponding to the same higher generations (N > 2).

  12. Mass extrapolation of quarks and leptons to higher generations

    International Nuclear Information System (INIS)

    Barik, N.

    1981-01-01

    An empirical mass formula is tested for the basic fermion sequences of charged quarks and leptons. This relation is a generalization of Barut's mass formula for the lepton sequence (e, μ, tau ....). It is found that successful mass extrapolation to the third and possibly to other higher generations (N > 2) can be obtained with the first and second generation masses as inputs, which predicts the top quark mass msub(t) to be around 20 GeV. This also leads to the mass ratios between members of two different sequences (i) and (i') corresponding to the same higher generations (N > 2). (author)

  13. Higher-speed coronal mass ejections and their geoeffectiveness

    Science.gov (United States)

    Singh, A. K.; Bhargawa, Asheesh; Tonk, Apeksha

    2018-06-01

    We have attempted to examine the ability of coronal mass ejections to cause geoeffectiveness. To that end, we have investigated total 571 cases of higher-speed (> 1000 km/s) coronal mass ejection events observed during the years 1996-2012. On the basis of angular width (W) of observance, events of coronal mass ejection were further classified as front-side or halo coronal mass ejections (W = 360°); back-side halo coronal mass ejections (W = 360°); partial halo (120°mass ejections were much faster and more geoeffective in comparison of partial halo and non-halo coronal mass ejections. We also inferred that the front-sided halo coronal mass ejections were 67.1% geoeffective while geoeffectiveness of partial halo coronal mass ejections and non-halo coronal mass ejections were found to be 44.2% and 56.6% respectively. During the same period of observation, 43% of back-sided CMEs showed geoeffectiveness. We have also investigated some events of coronal mass ejections having speed > 2500 km/s as a case study. We have concluded that mere speed of coronal mass ejection and their association with solar flares or solar activity were not mere criterion for producing geoeffectiveness but angular width of coronal mass ejections and their originating position also played a key role.

  14. Value Types in Higher Education--Students' Perspective

    Science.gov (United States)

    Dziewanowska, Katarzyna

    2017-01-01

    The purpose of the paper is to propose the service-dominant logic in marketing as a framework for analysing the value co-creation process in the higher education sector and present the results of a quantitative study (a survey) conducted among business students from four Polish public universities. The results of the study led to identification of…

  15. Values in Higher Education. The Wilson Lecture Series.

    Science.gov (United States)

    Wilson, O. Meredith

    The text of a lecture in the University of Arizona Wilson Lecture Series on values in higher education is presented, with responses by Richard H. Gallagher, Jeanne McRae McCarthy, and Raymond H. Thompson. The theme of the talk is that man is by evolution and by necessity a thinking animal, who now finds himself in a technologically dependent…

  16. Application of Mass Lumped Higher Order Finite Elements

    International Nuclear Information System (INIS)

    J. Chen, H.R. Strauss, S.C. Jardin, W. Park, L.E. Sugiyama, G. Fu, J. Breslau

    2005-01-01

    There are many interesting phenomena in extended-MHD such as anisotropic transport, mhd, 2-fluid effects stellarator and hot particles. Any one of them challenges numerical analysts, and researchers are seeking for higher order methods, such as higher order finite difference, higher order finite elements and hp/spectral elements. It is true that these methods give more accurate solution than their linear counterparts. However, numerically they are prohibitively expensive. Here we give a successful solution of this conflict by applying mass lumped higher order finite elements. This type of elements not only keep second/third order accuracy but also scale closely to linear elements by doing mass lumping. This is especially true for second order lump elements. Full M3D and anisotropic transport models are studied

  17. Mass generation and related issues from exotic higher dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Colatto, Luiz Paulo [Centro Federal de Educacao Tecnologica Celso Suckow da Fonseca (CEFET), Petropolis, RJ (Brazil); Andrade, Marco Antonio de [Universidade do Estado do Rio de Janeiro (UERJ), Resende, RJ (Brazil); Assis, Leonardo Paulo Guimaraes de; Helayel-Neto, Jose Abdalla [Centro Brasileiro de Pesquisas Fisicas(LAFEX/CBPF), Rio de Janeiro, RJ (Brazil). Coordenacao de Fisica Experimental de Altas Energias; Matheus-Valle, Jose Luiz [Universidade Federal de Juiz de Fora (UFJF), MG (Brazil); Rojas, Moises [Universidade Federal de Lavras, MG (Brazil)

    2011-07-01

    Full text: he main purpose of this work is to show that massless Dirac equation formulated for non-interacting Majorana-Weyl spinors in higher dimensions, particularly in D = 1 + 9 and D = 5 + 5, may yield to an interpretation of massive Majorana and Dirac spinors in D = 1 + 3 dimensions. The particular case of a dimensional reduction from D = 4 + 4 to D = 1 + 3 has already been fairly-well discussed in the literature. By adopting suitable representations of the Dirac matrices in higher dimensions, we pursue the investigation of which higher dimensional space-times and which metric signatures concerning massless Dirac equations in highermay induce massive spinors in D = 1+3 dimensions. The mixing of the chiral fermions in higher dimensions may induce a mechanism such that four massive Majorana fermions may show up and, at an appropriate limit an almost zero and a huge mass show up with corresponding left-handed and right-handed eigenstates. This mechanism could reassess a peculiar connection with the See-Saw scheme associated to neutrino with Majorana-type masses. The masses of the particle are fixed by the dimensional reduction scheme, which the decoupled dimensions contribute coordinates and depend on the mass invariants in lower dimensions. This proposal should allow us to understand the generation of hierarchies for the fermionic masses in D = 1 + 3, or in lower dimensions in general, starting from the constraints between the energy and the momentum in (n; n) dimensions. For the initial D = 5 + 5 Majorana-Weyl spinors framework using the Weyl representation to the Dirac matrices we observe an intriguing decomposition of space-time that result in two equivalent D = 1 + 4 massive spinors which mass term, in D = 1 + 3 included, is originated from the remained component and that could induce a Brane-World mechanism. (author)

  18. Zymomonas mobilis for fuel ethanol and higher value products.

    Science.gov (United States)

    Rogers, P L; Jeon, Y J; Lee, K J; Lawford, H G

    2007-01-01

    High oil prices, increasing focus on renewable carbohydrate-based feedstocks for fuels and chemicals, and the recent publication of its genome sequence, have provided continuing stimulus for studies on Zymomonas mobilis. However, despite its apparent advantages of higher yields and faster specific rates when compared to yeasts, no commercial scale fermentations currently exist which use Z. mobilis for the manufacture of fuel ethanol. This may change with the recent announcement of a Dupont/Broin partnership to develop a process for conversion of lignocellulosic residues, such as corn stover, to fuel ethanol using recombinant strains of Z. mobilis. The research leading to the construction of these strains, and their fermentation characteristics, are described in the present review. The review also addresses opportunities offered by Z. mobilis for higher value products through its metabolic engineering and use of specific high activity enzymes.

  19. Absolute values of neutrino masses: status and prospects

    International Nuclear Information System (INIS)

    Bilenky, S.M.; Giunti, C.; Grifols, J.A.; Masso, E.

    2003-01-01

    Compelling evidences in favor of neutrino masses and mixing obtained in the last years in Super-Kamiokande, SNO, KamLAND and other neutrino experiments made the physics of massive and mixed neutrinos a frontier field of research in particle physics and astrophysics. There are many open problems in this new field. In this review we consider the problem of the absolute values of neutrino masses, which apparently is the most difficult one from the experimental point of view. We discuss the present limits and the future prospects of β-decay neutrino mass measurements and neutrinoless double-β decay. We consider the important problem of the calculation of nuclear matrix elements of neutrinoless double-β decay and discuss the possibility to check the results of different model calculations of the nuclear matrix elements through their comparison with the experimental data. We discuss the upper bound of the total mass of neutrinos that was obtained recently from the data of the 2dF Galaxy Redshift Survey and other cosmological data and we discuss future prospects of the cosmological measurements of the total mass of neutrinos. We discuss also the possibility to obtain information on neutrino masses from the observation of the ultra high-energy cosmic rays (beyond the GZK cutoff). Finally, we review the main aspects of the physics of core-collapse supernovae, the limits on the absolute values of neutrino masses from the observation of SN1987A neutrinos and the future prospects of supernova neutrino detection

  20. Estimating RMR Values for Underground Excavations in a Rock Mass

    Directory of Open Access Journals (Sweden)

    Vítor Santos

    2018-02-01

    Full Text Available During underground excavations for civil or mining engineering purposes, the variations in rock mass quality are important, especially for the design of the most suitable support to be applied to ensure stability. The aim of this investigation is to model the expected behavior of the ground, and thus to predict the scenarios indicating potential variations in the quality of the rock mass during underground excavation. When considering the rock mass rating (RMR values observed at the excavation face in six study cases, which together total more than 27 km in length of underground excavation by drilling and blasting (D&B, and based on the observed RMR values at the face, the most probable value (1–100 is estimate for the RMR index at the five subsequent front advances. It is concluded that, up to about 20 m ahead of the current face, the quality of the rock mass for the next advances is close to the quality observed at the present face, and that, with increasing distance, there is a greater deviation of RMR values with respect to the quality observed at the current face.

  1. Higher body mass index associated with severe early childhood caries.

    Science.gov (United States)

    Davidson, Katherine; Schroth, Robert J; Levi, Jeremy A; Yaffe, Aaron B; Mittermuller, Betty-Anne; Sellers, Elizabeth A C

    2016-08-20

    Severe Early Childhood Caries (S-ECC) is an aggressive form of tooth decay in preschool children affecting quality of life and nutritional status. The purpose was to determine whether there is an association between Body Mass Index (BMI) and S-ECC. Children with S-ECC were recruited on the day of their slated dental surgery under general anesthesia. Age-matched, caries-free controls were recruited from the community. All children were participating in a larger study on nutrition and S-ECC. Analysis was restricted to children ≥ 24 months of age. Parents completed a questionnaire and heights and weights were recorded. BMI scores and age and gender adjusted BMI z-scores and percentiles were calculated. A p-value ≤ 0.05 was significant. Two hundred thirty-five children were included (141 with S-ECC and 94 caries-free). The mean age was 43.3 ± 12.8 months and 50.2 % were male. Overall, 34.4 % of participants were overweight or obese. Significantly more children with S-ECC were classified as overweight or obese when compared to caries-free children (p = 0.038) and had significantly higher mean BMI z-scores than caries-free children (0.78 ± 1.26 vs. 0.22 ± 1.36, p = 0.002). Those with S-ECC also had significantly higher BMI percentiles (69.0 % ± 29.2 vs. 56.8 % ± 31.7, p = 0.003). Multiple linear regression analyses revealed that BMI z-scores were significantly and independently associated with S-ECC and annual household income as were BMI percentiles. Children with S-ECC in our sample had significantly higher BMI z-scores than caries-free peers.

  2. Centile Curves and Reference Values for Height, Body Mass, Body Mass Index and Waist Circumference of Peruvian Children and Adolescents

    Science.gov (United States)

    Bustamante, Alcibíades; Freitas, Duarte; Pan, Huiqi; Katzmarzyk, Peter T.; Maia, José

    2015-01-01

    This study aimed to provide height, body mass, BMI and waist circumference (WC) growth centile charts for school-children, aged 4–17 years, from central Peru, and to compare Peruvian data with North-American and Argentinean references. The sample consisted of 8753 children and adolescents (4130 boys and 4623 girls) aged 4 to 17 years, from four Peruvian cities: Barranco, La Merced, San Ramón and Junín. Height, body mass and WC were measured according to standardized techniques. Centile curves for height, body mass, BMI and WC were obtained separately for boys and girls using the LMS method. Student t-tests were used to compare mean values. Overall boys have higher median heights than girls, and the 50th percentile for body mass increases curvilinearly from 4 years of age onwards. In boys, the BMI and WC 50th percentiles increase linearly and in girls, the increase presents a curvilinear pattern. Peruvian children are shorter, lighter and have higher BMI than their counterparts in the U.S. and Argentina; in contrast, age and sex-specific WC values are lower. Height, body mass and WC of Peruvian children increased with age and variability was higher at older ages. The growth patterns for height, body mass, BMI and WC among Peruvian children were similar to those observed in North-American and Argentinean peers. PMID:25761169

  3. Centile Curves and Reference Values for Height, Body Mass, Body Mass Index and Waist Circumference of Peruvian Children and Adolescents

    Directory of Open Access Journals (Sweden)

    Alcibíades Bustamante

    2015-03-01

    Full Text Available This study aimed to provide height, body mass, BMI and waist circumference (WC growth centile charts for school-children, aged 4–17 years, from central Peru, and to compare Peruvian data with North-American and Argentinean references. The sample consisted of 8753 children and adolescents (4130 boys and 4623 girls aged 4 to 17 years, from four Peruvian cities: Barranco, La Merced, San Ramón and Junín. Height, body mass and WC were measured according to standardized techniques. Centile curves for height, body mass, BMI and WC were obtained separately for boys and girls using the LMS method. Student t-tests were used to compare mean values. Overall boys have higher median heights than girls, and the 50th percentile for body mass increases curvilinearly from 4 years of age onwards. In boys, the BMI and WC 50th percentiles increase linearly and in girls, the increase presents a curvilinear pattern. Peruvian children are shorter, lighter and have higher BMI than their counterparts in the U.S. and Argentina; in contrast, age and sex-specific WC values are lower. Height, body mass and WC of Peruvian children increased with age and variability was higher at older ages. The growth patterns for height, body mass, BMI and WC among Peruvian children were similar to those observed in North-American and Argentinean peers.

  4. Higher Education Earnings Premium: Value, Variation, and Trends

    Science.gov (United States)

    Baum, Sandy

    2014-01-01

    Much of the current skepticism about the financial payoff of higher education emerges from recent media focus on young college graduates struggling to enter a weak labor market. This brief highlights some of the complexities underlying discussions of the return to the investment in postsecondary education and describes some of the variation in…

  5. Cleaning Management in Higher Education: Value for Money Study.

    Science.gov (United States)

    Scottish Higher Education Funding Council, Edinburgh.

    This report identifies key management issues for senior managers and heads of cleaning departments in developing and reviewing cleaning services to support improvement and enhance cost effectiveness. The cleaning costs incurred by higher education institutions (HEIs) represent 2.7 percent of the total spent nationally on cleaning services for both…

  6. Higher value in litigation for nuclear power plant proceedings

    International Nuclear Information System (INIS)

    Anon.

    1976-01-01

    The administrative court of Bavaria has rejected in its ruling of 19th August 1976 - No. 117 VI 76 - an appeal against the fixing of the value in litigation according to the judgment of the administrative court in Wuerzburg of 10th March 1976, and it has confirmed DM 20,000 as the disputed sum. The essential points of the grounds upon which the rejection is based are presented. (orig./HP) [de

  7. [Association between fat mass index and fat-free mass index values and cardiovascular risk in adolescents].

    Science.gov (United States)

    de Oliveira, Patrícia Morais; da Silva, Fabiana Almeida; Souza Oliveira, Renata Maria; Mendes, Larissa Loures; Netto, Michele Pereira; Cândido, Ana Paula Carlos

    2016-01-01

    To describe the association between fat mass index and fat-free mass index values and factors associated with cardiovascular risk in adolescents in the city of Juiz de Fora, Minas Gerais. Cross-sectional study with 403 adolescents aged 10-14 years, from public and private schools. Anthropometric, clinical, biochemical measurements were obtained, as well as self-reported time spent performing physical exercises, sedentary activities and sexual maturation stage. Regarding the nutritional status; 66.5% of the adolescents had normal weight; 19.9% were overweight and 10.2% were obese. For both genders, the fat mass index was higher in adolescents that had high serum triglycerides, body mass index and waist circumference. Adolescents that had anthropometric, clinical and biochemical characteristics considered to be of risk for the development of cardiovascular disease had higher values of fat mass index. Different methodologies for the assessment of body composition make health promotion and disease prevention more effective. Copyright © 2015 Sociedade de Pediatria de São Paulo. Publicado por Elsevier Editora Ltda. All rights reserved.

  8. Mass Intellectuality and Democratic Leadership in Higher Education

    OpenAIRE

    Hall, Richard; Winn, J.

    2016-01-01

    Higher education in the UK is in crisis. The idea of the public university is under assault, and both the future of the sector and its relationship to society are being gambled. Higher education is increasingly unaffordable, its historic institutions are becoming untenable, and their purpose is resolutely instrumental. What and who have led us to this crisis? What are the alternatives? To whom do we look for leadership in revealing those alternatives? This book critically analyses intell...

  9. Mass Media and Cultural Memory: Idealization of Values

    Directory of Open Access Journals (Sweden)

    Liljana Siljanovska

    2014-12-01

    Full Text Available The theoretical approach in defining the means for mass communication expressed in functionalist theory, especially in John Riley’s model, determines mass media as a social subsystem which is functionally connected with other systems in society that arises from their mutual conditionality and their causative and consequential connection with politics, economy, education, socialization and culture. The functions of articulating opinion by themselves problematize the creation of creative-thinking public because the imposition of topics, representation of individuals, values and norms of a culture, a space, a time is mediated by the ideological and functional mechanism of an organized structuring and transfer of messages simultaneously to as big an audience as possible. The vastness of the audience simply cannot by itself be understood as democratization of the culture in its broadest sense or simply because it is not a high, elite culture intended solely for a certain number of users.  It is that exact media reality, which almost always and exclusively is created through the selection of facts and values in relation to the audience and the factor of time, which simultaneously problematizes individual and collective memory. In the era of postmodernism and globalization of societies, media shaped content, in different mass media, especially on TV and the Internet, stimulate cultural development and pluralism of ideas in intercultural communication. However at the same time the setting of the stage for a media product, imposed by market logic of supply and demand erases the borders of difference, restructures the modalities of cultural identifiers and relativizes the dimensions of cultural identity through the unification of values transformed in surpassed or modern collective memories and concepts, such as – Balkanization, Americanization, Europeanization, civil society.

  10. Twenty-five new mass values from measurements performed with isochronous mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Diwisch, Marcel [Justus-Liebig-Universitaet Giessen (Germany); Knoebel, Ronja; Geissel, Hans; Plass, Wolfgang R.; Scheidenberger, Christoph [Justus-Liebig-Universitaet Giessen (Germany); GSI, Darmstadt (Germany); Patyk, Zygmunt [National Centre for Nuclear Research, NCBJ Swierk, Warszawa (Poland); Weick, Helmut [GSI, Darmstadt (Germany); Collaboration: FRS-ESR-Collaboration

    2016-07-01

    Masses of uranium fission fragments have been measured with the FRS-ESR facility at GSI. In order to increase the mass resolving power and particle identification for non-isochronous particles, Bρ-tagging was applied in one out of two experiments. A new method of data analysis, using a correlation matrix for the combined data set from the two experiments, has provided reliable experimental mass values for 25 different neutron-rich isotopes for the first time. The new masses were obtained for nuclides in the element range from Ge to Ce. The results have been compared with theoretical predictions. At the neutron shell N=82 the comparison of experimental data for tin and cadmium isotopes show both strong shell effects in agreement with spectroscopy experiments and modern shell-model calculations.

  11. Reforming Iraqi Journalism and Mass Communication Higher Education: Adapting the UNESCO Model Curricula for Journalism Education to Iraqi Higher Education

    Science.gov (United States)

    Pavlik, John V.; Laufer, Peter D.; Burns, David P.; Ataya, Ramzi T.

    2012-01-01

    Journalism and mass communication higher education in Iraq is well established but largely isolated from global developments since the 1970s. In the post-Iraq war period, the United Nations Educational, Scientific and Cultural Organization (UNESCO) implemented a multiyear project to work with the leadership of Iraqi higher education to help update…

  12. Monetizing French Distance Education: A Field Enquiry on Higher Education Value(s

    Directory of Open Access Journals (Sweden)

    Olivier Marty

    2014-04-01

    Full Text Available A field enquiry in French distance education allows us to analyze the evolution of a specific institution towards new public management: Parallel to a trend of free courseware and open education, there is a paradoxical reality of distance education monetization. Whereas history shows how traditional French education is a state controlled public good, a new policy is changing the organization’s culture towards a commercial and industrial activity. From inside the institution, we describe the cultural changes, with its human resources, accounting, and marketing dimensions. We relate debates about the institution’s business model within the economy of knowledge – selling either services or contents, focusing on the learner’s experience. Lastly, we analyze the notion of value underlying this monetization of a distance education institution: both the computing of a specific training’s value and the shared values of the workers binding up their collective identity.

  13. Masses, widths, and leptonic widths of the higher upsilon resonances

    International Nuclear Information System (INIS)

    Lovelock, D.M.J.; Horstkotte, J.E.; Klopfenstein, C.

    1985-01-01

    The masses, total widths, and leptonic widths of three triplet s-wave bb-bar states UPSILON(4S), UPSILON(5S), and UPSILON(6S) are determined from measurements of the e + e - annihilation cross section into hadrons for 10.55< W<11.25 GeV. The resonances are identified from potential model results and their properties are obtained with the help of a simplified coupled-channels calculation. We find M(4S) = 10.577 GeV, GAMMA(4S) = 25 MeV, GAMMA/sub e/e(4S) = 0.28 keV; M(5S) = 10.845 GeV, GAMMA(5S) = 110 MeV, GAMMA/sub e/e(5S) = 0.37 keV; M(6S) = 11.02 GeV, GAMMA(6S) = 90 MeV, GAMMA/sub e/e(6S) = 0.16 keV

  14. Masses, widths and leptonic widths of the higher upsilon resonances

    International Nuclear Information System (INIS)

    Klopfenstein, C.; Lovelock, D.M.J.; Horstkotte, J.E.

    1985-01-01

    The masses, total widths and leptonic widths of three triplet s-wave bb-bar states Υ(4S), Υ(5S) and Υ(6S) are determined by unfolding the cross section features observed in the hadronic cross section in the √s region betweeen 10.55 to 11.25 GeV. Both the identification of the resonances and the deduction of their properties rely on the validity of potential models' description of heavy quarkonium states which lie close (<0.6 GeV) to the open flavor threshold. The authors find M(4S) = 10.5774 +- 0.0008 GeV, Γ(4S) = 23 +- 2.3 MeV, Γ/sub ee/(4S) = 0.28 +- 0.04 keV; M(5S) = 10.845 +- 0.02 GeV, Γ(5S) = 110 +- 15 MeV, Γ/sub ee/(5S) = 0.37 +- 0.06 keV; M(6S) = 11.02 +- 0.03 GeV, Γ(6S) = 90 +- 20 MeV, Γ/sub ee/(6S) = 0.16 +- 0.04 keV. All errors are statistical only

  15. Reinterpreting Higher Education Quality in Response to Policies of Mass Education: The Australian Experience

    Science.gov (United States)

    Pitman, Tim

    2014-01-01

    This article explores the relationship between mass education, higher education quality and policy development in Australia in the period 2008-2014, during which access to higher education was significantly increased. Over this time, which included a change of national government, the discursive relationship between mass higher education and…

  16. The Perceived Value of Higher Education: The Voice of Chinese Students

    Science.gov (United States)

    Lai, Linda S. L.; To, W. M.; Lung, Jane W. Y.; Lai, T. M.

    2012-01-01

    This paper describes an exploratory study on the perceived value of higher education by Chinese students in Macao SAR, Guangzhou, Shanghai, and Taipei. Using responses from 316 students, we find that the Sheth-Newman-Gross Theory of Consumption Values explains how students perceive the services offered by higher education institutions. Students…

  17. Value of 18F-FDG PET imaging for differentiation of benign and malignant pancreatic mass

    International Nuclear Information System (INIS)

    Zhang Liying; Guo Wanhua; Guan Liang; Li Peiyong

    2002-01-01

    To evaluate the value of positron emission tomography (PET) imaging with 18 F-FDG in differentiation of benign and malignant pancreatic mass. 12 patients with pancreatic occupying lesion diagnosed by ultrasound or CT/MR including 7 pancreatic cancer and 5 pancreatitis underwent 18 F-FDG PET imaging. Visual interpretation and semiquantitative analysis by calculating the tumor/liver (T/L) ratio based on ROI were performed on attenuation corrected images. 9 positive findings were detected. Among them, 7 were confirmed to be cancer, but the other 2 were mass-forming pancreatitis. Final diagnoses of the 3 patients with negative findings were confirmed to be pancreatitis. The mean T/L ratio was 2.58 +- 0.95 in pancreatic cancer, significantly higher than that in pancreatitis (1.29 +- 0.87) (p = 0.037). With a T/L ratio cutoff value of 1.5, all 7 cancer patients were correctly categorized. However, one pancreatitis had T/L ratio higher than 1.5. 18 F-FEG PET imaging was a potential reliable method in differentiating benign or malignant pancreatic mass with high negative predictive value, but the specificity was limited. Semiquantitative analysis may improve the accuracy of the diagnosis

  18. Teaching Ethics in Higher Education Using the Values – Issues – Action (VIA Model

    Directory of Open Access Journals (Sweden)

    Crystal R Chambers

    2016-01-01

    Full Text Available Ethics content within higher education graduate programs can help higher education students as emerging leaders become more thoughtful about the decision making process. The purpose of the present manuscript is to explore one vehicle through which current and future higher education leaders can actively contemplate their values and how their values influence their actions when faced with an ethical challenge. The Values – Issue – Action (VIA Model for Ethical Decision Making is a tool for both classroom use and professional reflection through which one can reflect on their values (V and how those values shape how they perceive issues (I, and in turn shape their actions (A. Implications for teaching, learning, and practice are discussed.

  19. Newer methods for the characterization of higher molecular mass coal derivatives

    International Nuclear Information System (INIS)

    Bartle, K.D.

    1983-01-01

    Recent developments in a number of areas in the analytical chemistry of higher molecular mass coal derivatives are critically reviewed, viz. supercritical fluid chromatography, size-exclusion chromatography, charge-transfer fractionation, nmr spectroscopy, mass spectrometry and electrochemical analysis. (orig.) [de

  20. Personal Values, Social Capital, and Higher Education Student Career Decidedness: A New "Protean"-Informed Model

    Science.gov (United States)

    Fearon, Colm; Nachmias, Stefanos; McLaughlin, Heather; Jackson, Stephen

    2018-01-01

    This study investigates the role of personal values as motivational antecedents for understanding higher education (HE) student career decidedness among university business school (UBS) students. We propose a new "protean"-informed HE student career decidedness model for theorizing how both personal values and social capital mediators…

  1. Motives of Volunteering and Values of Work among Higher Education Students

    Science.gov (United States)

    Bocsi, Veronika; Fényes, Hajnalka; Markos, Valéria

    2017-01-01

    In this article, the motives for voluntary work and work values in higher education contexts are examined in a cross-border region in Central Eastern Europe. Our goal is to find out what kind of relationship exists between different types of volunteering and work values among young people. In the theoretical section, we deal with the definition of…

  2. Does Human Capital Theory Explain the Value of Higher Education? A South African Case Study

    Science.gov (United States)

    van der Merwe, Alex

    2010-01-01

    A perennial debate in the economics of education is whether human capital or screening/signalling theories best explain the value of schooling and hence the private demand for, in particular, higher education. Human capital theory proposes that formal training such as that offered by higher education institutions improves the productive capacity…

  3. The Value of Higher Education for Individuals and Society in the Asia-Pacific Region

    Science.gov (United States)

    Collins, Christopher S.; Bethke, Robert J.

    2017-01-01

    Central to this study is an exploration of the degree to which higher education is perceived as an individual and/or a collective value. Seminal literature supports the notion that colleges and universities are Western institutions. Throughout the Asia Pacific, higher education is expanding in a hybrid form in collectivist societies. This…

  4. Predictive value of body mass index to metabolic syndrome risk factors in Syrian adolescents.

    Science.gov (United States)

    Al-Bachir, Mahfouz; Bakir, Mohamad Adel

    2017-06-25

    Obesity has become a serious epidemic health problem in both developing and developed countries. There is much evidence that obesity among adolescents contributed significantly to the development of type 2 diabetes and coronary heart disease in adulthood. Very limited information exists on the prevalence of overweight, obesity, and associated metabolic risk factors among Syrian adolescents. Therefore, the purpose of this study was to determine the relationship between obesity determined by body mass index and the major metabolic risk factors among Syrian adolescents. A cross-sectional study of a randomly selected sample of 2064 apparently healthy Syrian adolescents aged 18 to 19 years from Damascus city, in Syria, was performed. Body mass index and blood pressure were measured. Serum concentrations of glucose, triglycerides, total cholesterol, high-density lipoprotein-cholesterol, and low-density lipoprotein-cholesterol were determined. Metabolic syndrome was defined using the national criteria for each determined metabolic risk factor. Individuals with a body mass index 25 to 29.9 were classified as overweight, whereas individuals with a body mass index ≥30 were classified as obese. A receiver operating characteristics curve was drawn to determine appropriate cut-off points of the body mass index for defining overweight and obesity, and to indicate the performance of body mass index as a predictor of risk factors. The obtained data showed that blood pressure and the overall mean concentrations of fasting blood sugar, triglycerides, cholesterol, low-density lipoprotein-cholesterol, and triglycerides/high-density lipoprotein-cholesterol were significantly higher in overweight and obese adolescent groups (p index and some metabolic risks, the data suggest the best body mass index cut-offs ranged between 23.25 and 24.35 kg/m 2 . A strong association between overweight and obesity as determined by body mass index and high concentrations of metabolic syndrome

  5. THE VALUE OF ULTRASOUND MAMMOGRAPHY IN PALPABLE BREAST MASSES

    NARCIS (Netherlands)

    VANOORD, JC; VANDERVLIET, AM; THYN, CJP; MAK, B; HOOGEBOOM, GJ

    Between January 1987 and May 1988 a prospective study was carried out on 232 women with a palpable breast mass. They underwent physical examination, x-ray mammography and ultrasound mammography. The results of each study were interpreted independently by separate observers, and consensus was

  6. Higher surface mass balance of the Greenland ice sheet revealed by high - resolution climate modeling

    NARCIS (Netherlands)

    Ettema, Janneke; van den Broeke, Michiel R.; van Meijgaard, Erik; van de Berg, Willem Jan; Bamber, Jonathan L.; Box, Jason E.; Bales, Roger C.

    2009-01-01

    High‐resolution (∼11 km) regional climate modeling shows total annual precipitation on the Greenland ice sheet for 1958–2007 to be up to 24% and surface mass balance up to 63% higher than previously thought. The largest differences occur in coastal southeast Greenland, where the much higher

  7. Measuring the Total Economic Value of State-Funded Higher Education in Iowa

    OpenAIRE

    Swenson, David A.

    2011-01-01

    This is an evaluation of the statewide total economic value of state-funded higher education in Iowa. The analysis is based on Fiscal Year 2010 final budgeted values for Iowa's three Board of Regents universities and their teaching hospital, as well as the state's 15 community colleges. Final budget year data were obtained from the respective state universities' web sites, from the Board of Regents, and from the Annual Condition of Iowa's Community Colleges, 2010, report published by the Iowa...

  8. The Relationship Between Higher Education Students’ Consumption Values and Levels of Their Satisfaction

    Directory of Open Access Journals (Sweden)

    Necati CEMALOĞLU

    2014-12-01

    Full Text Available The purpose of this study is to determine the relationships between the as consumers of education of higher education students’ consumption values and levels of their satisfaction. The population of this study is consist of 421 students who are studying at Akdeniz University, Faculty of Science, Biology in the academic year 2012-2013. Sample of this study is 156 students who selected by simple random sampling method. Descriptive statistics, Pearson-Product Moment correlation coefficient and multiple regression analysis were performed to analyze the data. According to the results of study, that students have consumption values in dimension of conditional value, functional value-the image and functional value-the experiential; relatively they have low consumptions values in dimension of functional value-the usefulness of a degree, epistemic value, social value have emerged. Besides the students’ are partly satisfied services offered by university; a positive and significant relationship between students’ perceptions of consumer value and satisfaction was found out

  9. The Wisdom of e-crowds: Can Masses Create Value?

    Directory of Open Access Journals (Sweden)

    Wieczerzycki Marcin

    2016-09-01

    Full Text Available With the rising popularity of the Internet, interactions between companies and their consumers have become more common and meaningful. Researchers often tend to apply the metaphor of community to these on-line networks of B2C relationships. However, this term implies durability and a long-term orientation. It does not cover more incidental, short-lived groups of consumers, who therefore should not be treated as communities. The purpose of this paper is to explore the ability of these short-term, collective consumer phenomena (addressed as e-crowds within the scope of this paper to create value. Based on a critical literature analysis that considers works from several different fields of knowledge (including management, economics, psychology and media studies and empirical examples, we argue that while lacking a complex internal organization, e-crowds are capable of creating use, exchange and sign value when certain conditions are met. However, they are equally likely to perform value-destroying activities, which present real risks for companies that interact with e-crowds.

  10. The nonlocal boundary value problems for strongly singular higher-order nonlinear functional-differential equations

    Czech Academy of Sciences Publication Activity Database

    Mukhigulashvili, Sulkhan

    -, č. 35 (2015), s. 23-50 ISSN 1126-8042 Institutional support: RVO:67985840 Keywords : higher order functional differential equations * Dirichlet boundary value problem * strong singularity Subject RIV: BA - General Mathematics http://ijpam.uniud.it/online_issue/201535/03-Mukhigulashvili.pdf

  11. Students' Trust, Value and Loyalty: Evidence from Higher Education in Brazil

    Science.gov (United States)

    Sampaio, Claudio Hoffmann; Perin, Marcelo Gattermann; Simoes, Claudia; Kleinowski, Hamilton

    2012-01-01

    This paper focuses on students' perception of value, trust and loyalty and how these constructs connect in the context of higher education in Brazil. For this endeavor we conducted a survey among undergraduate business students in Brazil. The findings suggest that trust in faculty and trust in staff positively affects students' trust in management…

  12. Public Concepts of the Values and Costs of Higher Education, 1963-1974. A Preliminary Analysis.

    Science.gov (United States)

    Minor, Michael J.; Murray, James R.

    Statistical data are presented on interviews conducted through the Continuous National Survey (CNS) at the National Opinion Research Center in Chicago and based on results reprinted from "Public Concepts of the Values and Costs of Higher Education," by Angus Campbell and William C. Eckerman. The CNS results presented in this report are…

  13. Normative Values in Teachers' Conceptions of Teaching and Learning in Higher Education: A Belief System Approach

    Science.gov (United States)

    Schwieler, Elias; Ekecrantz, Stefan

    2011-01-01

    The effects of teachers' normative values and emotive reactions on teaching in higher education have received relatively little research attention. The focus is often on descriptive beliefs such as conceptions of teaching and their inter-relations with practice. In this study, which is illustrated by a heuristic model, a belief system approach is…

  14. Determining Perceptual Gaps of Service Quality and Value in Higher Education: A Midwestern Bible College

    Science.gov (United States)

    McIntosh, Benjamin T.

    2017-01-01

    This doctoral research project examined perceptual gaps of service quality and value in the context of higher education. The researcher performed quantitative analysis of survey data gathered from students at a small, Midwestern Bible college. Students self-selected to participate in this research project and, using class status as an independent…

  15. On the Practices and Challenges of Measuring Higher Education Value Added: The Case of Colombia

    Science.gov (United States)

    Shavelson, Richard J.; Domingue, Benjamin W.; Mariño, Julián P.; Molina Mantilla, Adriana; Morales Forero, Andrés; Wiley, Edward E.

    2016-01-01

    Changes in the nature of higher education are leading towards increased interest in the assessment of student learning. This study considers an attempt to apply value-added models for the purposes of comparing student learning across institutions, taking care to discuss special considerations inherent to the application of these models to higher…

  16. The Culture of Learning Continuum: Promoting Internal Values in Higher Education

    Science.gov (United States)

    Sagy, Ornit; Kali, Yael; Tsaushu, Masha; Tal, Tali

    2018-01-01

    This study endeavors to identify ways to promote a productive learning culture in higher education. Specifically, we sought to encourage development of internal values in students' culture of learning and examine how this can promote their understanding of scientific content. Set in a high enrollment undergraduate biology course, we designed a…

  17. The Value Orientation of Higher Vocational Education Evaluation: A Textual Analysis of an Evaluation Program

    Science.gov (United States)

    Wang, Yonglin; Wang, Zhanjun

    2016-01-01

    Education evaluation should be based on human development and revolve around educational institutions integrating two dimensions, the development needs of the nation and society, and the logic and laws of self-development. The value orientation of higher vocational education evaluation in China is actually expressed through enhancing quality…

  18. "Low-Impact Communities" and Their Value to Experiential Education for Sustainability in Higher Education

    Science.gov (United States)

    Cook, Robert; Cutting, Roger

    2014-01-01

    This paper reports on a year-long research project that investigated the value of experiential engagement with "alternative" communities which derive a high degree of self-reliance from working closely with their own local natural resources. Opportunities for higher education students to explore these communities were developed and the…

  19. Perceptions toward the Value of Higher Education for Hotel Professionals in Las Vegas: A Case Study

    Science.gov (United States)

    Deel, Gary Lee

    2015-01-01

    This study concerns a qualitative investigation of the views toward higher education and its importance to hospitality career success among hotel professionals in the Las Vegas, Nevada area. Existing literature supported the premise that education may be important to professional career success in several different ways, and that values concerning…

  20. The focal boundary value problem for strongly singular higher-order nonlinear functional-differential equations

    Czech Academy of Sciences Publication Activity Database

    Mukhigulashvili, Sulkhan; Půža, B.

    2015-01-01

    Roč. 2015, January (2015), s. 17 ISSN 1687-2770 Institutional support: RVO:67985840 Keywords : higher order nonlinear functional-differential equations * two-point right-focal boundary value problem * strong singularity Subject RIV: BA - General Mathematics Impact factor: 0.642, year: 2015 http://link.springer.com/article/10.1186%2Fs13661-014-0277-1

  1. Study of Ethical Values and Practices in Academic Programmes at a Higher Learning Institution

    Science.gov (United States)

    Narayanasamy, Kogilah; Shetty, M. V.

    The study on ethical values in academic programmes has attracted the attention of many researchers throughout the world especially in view of its important role today. Many academic programmes today focus on how to make profit both for the individual and the organization and on how to increase the firm`s market share and shareholders value and in the process may compromise on their ethical values and have unethical practices. Thus, this study is undertaken to evaluate the extent of integration of ethical values in the academic programmes of the higher learning operating institution involved with post graduate and higher level programs. The impact of demographics and race of the lecturer and students have been separately ascertained. The sample has been taken from one college, rated to be high in ethical values and practices, a sample of 120 students and 31 lecturers from a leading college (reputed for ethical values) have been collated and analyzed for validation of the objectives. The explanation on ethics has been done to a large extent in the study. The study also indicates the number of higher learning institutions to indicate the extent of impact if these issues are appropriately addressed. Government policy in this regard also needs to be reviewed and improved to avoid deterioration of ethical values and practices in the dynamic market place of today. This study review that, the level at which lecturers at the institutions have high ethical values and do incorporate it in their lectures and discussions in the classroom. The impact of demographic factors on the ethical values and practice of the lecturers have useful insights for academic staff recruitment and staff training. On the other hand, students` ethical values and behavior is a cause for concern to everyone as these future pillars of the nation have been found to have their ethical values and practices at low levels. The implications for the college management as to consider further emphasis on the

  2. Higher body mass, older age and higher monounsaturated fatty acids intake reflect better quantitative ultrasound parameters in Inuit preschoolers

    Directory of Open Access Journals (Sweden)

    Jessy El Hayek

    2012-07-01

    Full Text Available Objectives. Investigate the effects of selected factors associated with quantitative ultrasound parameters among Inuit preschoolers living in Arctic communities (56° 32′–72° 40′N. Materials and methods. Children were selected randomly in summer and early fall (n=296. Dietary intake was assessed through the administration of a 24-h dietary recall (24-h recall and a food frequency questionnaire (FFQ. Anthropometry was measured using standardized procedures. Plasma 25-hydroxy vitamin D (25(OHD and parathyroid hormone (PTH were measured using a chemiluminescent assay (Liaison, Diasorin. Quantitative ultrasound parameters were measured using Sahara Sonometer, (Hologic Inc.. Results. Children divided by speed of sound (SoS and broadband ultrasound attenuation (BUA quartiles were not different for age (years, sex (M/F, calcium (mg/d and vitamin D intake (µg/d and plasma 25(OHD concentration (nmol/L. However, children in the highest BUA and SoS quartile had higher body mass index (BMI compared to those in quartile 1. Using multivariate linear regression, higher BMI, older age and monounsaturated fatty acids (MUFA intake were predictors of BUA while only BMI was a predictor of SoS. Conclusions. Further investigation assessing intakes of traditional foods (TF and nutrients affecting bone parameters along with assessment of vitamin D status of Inuit children across seasons is required.

  3. Packaging and Unpackaging Knowledge in Mass Higher Education--A Knowledge Management Perspective

    Science.gov (United States)

    Guzman, Gustavo; Trivelato, Luiz F.

    2011-01-01

    The progressive deployment of market-oriented regulatory frameworks in mass Higher Education Institutions (MHEI hereafter) triggered, in a wide variety of forms and degrees, the application of Knowledge Management principles in MHEI. This means the application of the knowledge "codification strategy", where the focus is on the economies of the…

  4. Visualization and processing of higher order descriptors for multi-valued data

    CERN Document Server

    Schultz, Thomas

    2015-01-01

    Modern imaging techniques and computational simulations yield complex multi-valued data that require higher-order mathematical descriptors. This book addresses topics of importance when dealing with such data, including frameworks for image processing, visualization, and statistical analysis of higher-order descriptors. It also provides examples of the successful use of higher-order descriptors in specific applications and a glimpse of the next generation of diffusion MRI. To do so, it combines contributions on new developments, current challenges in this area, and state-of-the-art surveys.   Compared to the increasing importance of higher-order descriptors in a range of applications, tools for analysis and processing are still relatively hard to come by. Even though application areas such as medical imaging, fluid dynamics, and structural mechanics are very different in nature they face many shared challenges. This book provides an interdisciplinary perspective on this topic with contributions from key rese...

  5. The value trade-off in higher education service: A qualitative intercultural approach to students’ perceptions

    Directory of Open Access Journals (Sweden)

    Danni Li

    2016-08-01

    Full Text Available Purpose: Higher Education Institutions have become a highly competitive market, where consumers (i.e. students are highly involved in their choices, and managers need to focus on competitive edges. This paper aims to understand the factors that influence student choice behaviour and fulfil student expectations of customer value in higher education institutions (HEIs. Design/methodology/approach: with qualitative information (focus groups collected from international students of several universities in Spain, Britain and China, the paper investigates the formation of customer value, as a trade-off between benefits and costs. This qualitative approach aims first at assessing this particular service through the concept of value through verifying both the positive and negative dimensions of HE, and second, to comment on the intercultural aspects of this dual approach to higher education consumption. Findings: the results show different levels of benefits: the functional value generally comes from infrastructures and good teachers that offer abundant practical experiences. The benefits from quality education also derived from teamwork with the colleagues who possess equal academic strength. Social benefits come from experiences outside the academic environment, working with people from different cultural backgrounds who have different perspectives. Emotional rewards come from University reputation and relationships with instructors. Costs of time and effort are differently seen across programs and vary widely upon nationalities and cultural backgrounds. Practical implications: since the competitive environments are fast becoming more and more complex added to the fact that it changes rapidly and dynamically, to concentrate on a few key elements are most important to the organizations survival. Different values of customers in different countries suggest that the strategy used by the corporation in a certain country, may not be apply to another

  6. Obesity as defined by waist circumference but not body mass index is associated with higher renal mass complexity.

    Science.gov (United States)

    Bertrand, Laura A; Thomas, Lewis J; Li, Peng; Buchta, Claire M; Boi, Shannon K; Orlandella, Rachael M; Brown, James A; Nepple, Kenneth G; Norian, Lyse A

    2017-11-01

    Obesity, typically defined as a body mass index (BMI)≥30kg/m 2 , is an established risk factor for renal cell carcinoma (RCC) but is paradoxically linked to less advanced disease at diagnosis and improved outcomes. However, BMI has inherent flaws, and alternate obesity-defining metrics that emphasize abdominal fat are available. We investigated 3 obesity-defining metrics, to better examine the associations of abdominal fat vs. generalized obesity with renal tumor stage, grade, or R.E.N.A.L. nephrometry score. In a prospective cohort of 99 subjects with renal masses undergoing resection and no evidence of metastatic disease, obesity was assessed using 3 metrics: body mass index (BMI), radiographic waist circumference (WC), and retrorenal fat (RRF) pad distance. R.E.N.A.L. nephrometry scores were calculated based on preoperative CT or MRI. Univariate and multivariate analyses were performed to identify associations between obesity metrics and nephrometry score, tumor grade, and tumor stage. In the 99 subjects, surgery was partial nephrectomy in 51 and radical nephrectomy in 48. Pathology showed benign masses in 11 and RCC in 88 (of which 20 had stage T3 disease). WC was positively correlated with nephrometry score, even after controlling for age, sex, race, and diabetes status (P = 0.02), whereas BMI and RRF were not (P = 0.13, and P = 0.57, respectively). WC in stage T2/T3 subjects was higher than in subjects with benign masses (P = 0.03). In contrast, subjects with Fuhrman grade 1 and 2 tumors had higher BMI (Pobesity measured by WC, but not BMI or RRF, is associated with increased renal mass complexity. Tumor Fuhrman grade exhibited a different trend, with both high WC and BMI associated with lower-grade tumors. Our findings indicate that WC and BMI are not interchangeable obesity metrics. Further evaluation of RCC-specific outcomes using WC vs. BMI is warranted to better understand the complex relationship between general vs. abdominal obesity and RCC

  7. Utility of Higher Harmonics in Electrospray Ionization Fourier Transform Electrostatic Linear Ion Trap Mass Spectrometry.

    Science.gov (United States)

    Dziekonski, Eric T; Johnson, Joshua T; McLuckey, Scott A

    2017-04-18

    Mass resolution (M/ΔM fwhm) is observed to linearly increase with harmonic order in a Fourier transform electrostatic linear ion trap (ELIT) mass spectrometer. This behavior was predicted by Grosshans and Marshall for frequency-multiple detection in a Fourier transform ion cyclotron resonance mass spectrometer only for situations when the prominent mechanism for signal decay is ion ejection from the trap. As the analyzer pressure in our ELIT chamber is relatively high, such that collisional scattering and collision-induced dissociation are expected to underlie much of the ion loss, we sought to explore the relationship between harmonic order and mass resolution. Mass resolutions of 36 900 (fundamental), 75 850 (2nd harmonic), and 108 200 (3rd harmonic) were obtained for GdO + (avg. m/z 173.919) with a transient length of 300 ms. To demonstrate that the mass resolution was truly increasing with harmonic order, the unresolved isotopes at the fundamental distribution of cytochrome c +8 (m/z ∼ 1549) were nearly baseline, resolved at the third harmonic (mass resolution ≈ 23 000) with a transient length of only 200 ms. This experiment demonstrates that, when the ion density is sufficiently low, ions with frequency differences of less than 4 Hz remain uncoalesced. Higher harmonics can be used to increase the effective mass resolution for a fixed transient length and thereby may enable the resolution of closely spaced masses, determination of a protein ion's charge state, and study of the onset of peak coalescence when the resolution at the fundamental frequency is insufficient.

  8. From elite to mass to universal higher education: from distance to open education

    Directory of Open Access Journals (Sweden)

    Larry Cooperman

    2014-01-01

    Full Text Available In 1970, Martin Trow, a professor at the University of California, Berkeley, identified a transition “underway in every advanced society, from elite to mass higher education and subsequently to universal access.” This article adapts this framework of the historical and structural development of higher education as a phased process in which absolute and relative growth of university enrollment transforms the institutions of higher education and alters its functions. The transition to universal access may support economic development, social mobility and greater income equality, in turn buttressing even the institution of democracy. Arriving at those optimal social outcomes is not automatic, however, because of a variety of remaining issues: how universality of higher education translates to economic growth and social equality. The problem of the ‘next 1%,’ shorthand for the continued entrance of new social layers into higher education presents novel challenges that ‘access’ alone may not solve.

  9. Experimental Demonstration of Higher Precision Weak-Value-Based Metrology Using Power Recycling

    Science.gov (United States)

    Wang, Yi-Tao; Tang, Jian-Shun; Hu, Gang; Wang, Jian; Yu, Shang; Zhou, Zong-Quan; Cheng, Ze-Di; Xu, Jin-Shi; Fang, Sen-Zhi; Wu, Qing-Lin; Li, Chuan-Feng; Guo, Guang-Can

    2016-12-01

    The weak-value-based metrology is very promising and has attracted a lot of attention in recent years because of its remarkable ability in signal amplification. However, it is suggested that the upper limit of the precision of this metrology cannot exceed that of classical metrology because of the low sample size caused by the probe loss during postselection. Nevertheless, a recent proposal shows that this probe loss can be reduced by the power-recycling technique, and thus enhance the precision of weak-value-based metrology. Here we experimentally realize the power-recycled interferometric weak-value-based beam-deflection measurement and obtain the amplitude of the detected signal and white noise by discrete Fourier transform. Our results show that the detected signal can be strengthened by power recycling, and the power-recycled weak-value-based signal-to-noise ratio can surpass the upper limit of the classical scheme, corresponding to the shot-noise limit. This work sheds light on higher precision metrology and explores the real advantage of the weak-value-based metrology over classical metrology.

  10. Energy conversion through mass loading of escaping ionospheric ions for different Kp values

    Science.gov (United States)

    Yamauchi, Masatoshi; Slapak, Rikard

    2018-01-01

    Fload. Since Fload significantly increases for increased flux of extreme ultraviolet (EUV) radiation, high EUV flux may significantly enhance this positive feedback. Therefore, the ion escape rate and the energy extraction by mass loading during ancient Earth, when the Sun is believed to have emitted much higher EUV flux than at present, could have been even higher than the currently available highest values based on Kp = 9. This raises a possibility that the ion escape has substantially contributed to the evolution of the Earth's atmosphere.

  11. The perceptions of the meaning and value of analytics in New Zealand higher education institutions

    Directory of Open Access Journals (Sweden)

    Hamidreza Mahroeian

    2017-10-01

    Full Text Available Abstract This article presents the current perceptions on the value of analytics and their possible contribution to the higher education sector in New Zealand. Seven out of eight research-intensive public universities in New Zealand took part in the study. Participants included senior management and those who have some role associated with decision-making within higher education (N = 82. The study found inconsistent understanding of the meaning of analytics across participants. In particular, three forms of perceptions of analytics were identified: structural; functional and structural-functional. It was evident that some participants viewed analytics in its structural elements such as statistics, metrics, trends, numbers, graph, and any relevant information/data to enhance better decision-making, whereas other participants perceived the notion of analytics in terms of functional aspect; as means to an end, a process to use the data to gain insights and taking action on complex problems, yet a third group viewed analytics from both structural-functional perspectives. These kinds of perceptions have to a larger extent influenced participants’ views on the value of analytics in shaping policy and practice. Also, literature has addressed a number of possible challenges associated with the large-scale institutional implementation of analytics. These challenges were: difficulties in extracting data from multiple databases, maintaining data quality, ethical and privacy issues, and lack of professional development opportunities. This article aims to broadly contribute to a better understanding of current perception and value of analytics in higher education, and in particular within the New Zealand context.

  12. Variational Homotopy Perturbation Method for Solving Higher Dimensional Initial Boundary Value Problems

    Directory of Open Access Journals (Sweden)

    Muhammad Aslam Noor

    2008-01-01

    Full Text Available We suggest and analyze a technique by combining the variational iteration method and the homotopy perturbation method. This method is called the variational homotopy perturbation method (VHPM. We use this method for solving higher dimensional initial boundary value problems with variable coefficients. The developed algorithm is quite efficient and is practically well suited for use in these problems. The proposed scheme finds the solution without any discritization, transformation, or restrictive assumptions and avoids the round-off errors. Several examples are given to check the reliability and efficiency of the proposed technique.

  13. Mass size and occurrence of necrosis as discerning values to distinguish between a malignant mass and a bening one by CT. Adrenal mass as the only clinicoradiologic finding

    International Nuclear Information System (INIS)

    Rodriguez Gonzalez, R.

    1991-01-01

    We have studied 123 adult patients with 137 adrenal masses, analyzing mass size and ocurrence of necrosis. We have proved that necrosis depends, although not perfectly, on the mass size. Though 81-83% of masses lasser than 3-4 cm are bening, size alone has no a great discerning value to distinguish between a malignant mass and a bening one, other clinical and radiologic data being more decisive. In 37 patients, with 38 adrenal masses, there was no other findings which could information on the type of treatment to choose. From the adrenal masses of these last patients we carried out a diagnostic efficiency curve (DEC) which showed that the critical size in order to distinguish between a bening mass and a malignant one could be 5 cm. After an evaluation of the results obtained in the 137 adrenal masses, we think that is wiser to choose a critical size of 4 cm to establish an acting strategy in the patients with an adrenal mass as the only clinicoradiologic finding. (Author)

  14. Application values of 99mTc-methoxyisobutylisonitrile imaging for differentiating benign and malignant thymic masses.

    Science.gov (United States)

    Lu, Chenghui; Wang, Xufu; Liu, Bin; Liu, Xinfeng; Wang, Guoming; Zhang, Qin

    2017-08-01

    The aim of the present study was to investigate the application value of 99m Tc-methoxyisobutylisonitrile (MIBI) imaging to differentiate between benign and malignant thymic masses. A total of 32 patients with space-occupying mediastinal masses were enrolled and early and delayed-phase images were collected following injection with the imaging agent. The tumor to background ratio (T/N) values at the different phases were also recorded. The sensitivity of the qualitative analysis to distinguish between benign and malignant thymic masses was 95.24%, with specificity as 90.91%. The T/N values in the early and delayed phases were not significantly different in the group with benign thymic masses, but demonstrated statistical significant differences in the groups with low- and intermediate-grade malignant thymic masses. The T/N values at the above early and delayed phase were significantly different between the benign and low-grade malignancy groups, as well as between low- and moderate-grade malignancy groups. Those between the benign and moderate-grade malignancy groups demonstrated no significant difference. 99m Tc-MIBI imaging was able to differentiate between benign and malignant thymic masses, and the simultaneous semi-quantitative analysis of the T/N values of the tumors may be able to initially determine the degree of malignancy of thymoma.

  15. Appendicular Skeletal Muscle Mass Reference Values and the Peak Muscle Mass to Identify Sarcopenia among Iranian Healthy Population.

    Science.gov (United States)

    Shafiee, Gita; Ostovar, Afshin; Heshmat, Ramin; Keshtkar, Abbas Ali; Sharifi, Farshad; Shadman, Zhaleh; Nabipour, Iraj; Soltani, Akbar; Larijani, Bagher

    2018-01-01

    Sacopenia is a common problem in elderly with the adverse outcomes. The objective of this study was to estimate the peak appendicular skeletal muscle mass (ASM) and age of its attainment by sex among the Iranian population. A total of 691 men and women aged 18-94 years participated in this cross-sectional, population-based study in Bushehr, Iran. ASM was measured by dual X-ray absorptiometry. Cutoff points for men and women were established considering two standard deviations (SDs) below the mean values of the skeletal muscle index (SMI) for young reference groups. The relationship between ASM and age was described by the second-degree regression models. Two SDs below the mean SMIs of reference groups were as cutoff values of low muscle mass in Iranian population. The peak ASM values were 21.35 ± 0.12 Kg and 13.68 ± 0.10 Kg, and the age at peak ASM were 26 (24-28) years and 34 (33-35) years for men and women, respectively. Mean and SD of SMI in those ages were 7.01 ± 0.02 Kg/m 2 and 5.44 ± 0.02 Kg/m 2 among men and women, respectively. Calculated cutoff values of low muscle mass among the Iranian population were 7.0 Kg/m 2 and 5.4 Kg/m 2 among men and women, respectively. Iranian reference values of SMI for both genders were similar to Asia Working Group for Sarcopenia recommendation and lower than the United States and European values. Further studies from different nations and the Middle East countries are needed to obtain reference values for populations, enabling the researchers for comparison and also more valid reports on sarcopenia prevalence.

  16. Fat mass to fat-free mass ratio reference values from NHANES III using bioelectrical impedance analysis.

    Science.gov (United States)

    Xiao, J; Purcell, S A; Prado, C M; Gonzalez, M C

    2017-10-06

    Low fat-free mass (FFM) or high fat mass (FM) are abnormal body composition phenotypes associated with morbidity. These conditions in combination lead to worse health outcomes, and can be identified by a high FM/FFM ratio. Here, we developed sex, age, and body mass index (BMI) stratified, population-based FM/FFM reference values using bioelectrical impedance analysis (BIA) measurements. White, non-Hispanic individuals aged 18-90 years old with data for weight, stature and BIA resistance measures from the third National Health and Nutrition Examination Survey (NHANES) III were included. Previously validated and sex-specific BIA prediction equations were used to calculate FM and FFM. FM/FFM values were generated at 5th, 50th and 95th percentiles for each sex, age (18-39.9, 40-59.9, 60-69.9 and 70-90 years), and BMI category (underweight, normal weight, overweight, class I/II and class III obesity). A total of 6372 individuals who had estimated FM and FFM values were identified (3366 females, 3006 males). Median values of FM/FFM were 0.24 and 0.40 for young (≤39.9 years) males and females with normal BMI, and 0.34 for males and 0.59 for females who were overweight. For elderly individuals aged >70 years, median FM/FFM for males and females were respectively 0.28 and 0.45 for those with normal BMI, and 0.37 and 0.61 for those in the overweight category. These FM/FFM reference values provide information on body composition characteristics that account for age, sex and BMI, which can be useful to identify individuals at risk for body composition abnormalities. Copyright © 2017 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

  17. Energy conversion through mass loading of escaping ionospheric ions for different Kp values

    Directory of Open Access Journals (Sweden)

    M. Yamauchi

    2018-01-01

    K from the solar wind to the current system by the increased Fload. Since Fload significantly increases for increased flux of extreme ultraviolet (EUV radiation, high EUV flux may significantly enhance this positive feedback. Therefore, the ion escape rate and the energy extraction by mass loading during ancient Earth, when the Sun is believed to have emitted much higher EUV flux than at present, could have been even higher than the currently available highest values based on Kp = 9. This raises a possibility that the ion escape has substantially contributed to the evolution of the Earth's atmosphere.

  18. Greenhouse crop residues: Energy potential and models for the prediction of their higher heating value

    Energy Technology Data Exchange (ETDEWEB)

    Callejon-Ferre, A.J.; Lopez-Martinez, J.A.; Manzano-Agugliaro, F. [Departamento de Ingenieria Rural, Universidad de Almeria, Ctra. Sacramento s/n, La Canada de San Urbano, 04120 Almeria (Spain); Velazquez-Marti, B. [Departamento de Ingenieria Rural y Agroalimentaria, Universidad Politecnica de Valencia, Camino de Vera s/n, 46022 Valencia (Spain)

    2011-02-15

    Almeria, in southeastern Spain, generates some 1,086,261 t year{sup -1} (fresh weight) of greenhouse crop (Cucurbita pepo L., Cucumis sativus L., Solanum melongena L., Solanum lycopersicum L., Phaseoulus vulgaris L., Capsicum annuum L., Citrillus vulgaris Schrad. and Cucumis melo L.) residues. The energy potential of this biomass is unclear. The aim of the present work was to accurately quantify this variable, differentiating between crop species while taking into consideration the area they each occupy. This, however, required the direct analysis of the higher heating value (HHV) of these residues, involving very expensive and therefore not commonly available equipment. Thus, a further aim was to develop models for predicting the HHV of these residues, taking into account variables measured by elemental and/or proximate analysis, thus providing an economically attractive alternative to direct analysis. All the analyses in this work involved the use of worldwide-recognised standards and methods. The total energy potential for these plant residues, as determined by direct analysis, was 1,003,497.49 MW h year{sup -1}. Twenty univariate and multivariate equations were developed to predict the HHV. The R{sup 2} and adjusted R{sup 2} values obtained for the univariate and multivariate models were 0.909 and 0.946 or above respectively. In all cases, the mean absolute percentage error varied between 0.344 and 2.533. These results show that any of these 20 equations could be used to accurately predict the HHV of crop residues. The residues produced by the Almeria greenhouse industry would appear to be an interesting source of renewable energy. (author)

  19. The association between higher body mass index and poor school performance in high school students.

    Science.gov (United States)

    Tonetti, L; Fabbri, M; Filardi, M; Martoni, M; Natale, V

    2016-12-01

    This study aimed to examine the association between body mass index (BMI) and school performance in high school students by controlling for relevant mediators such as sleep quality, sleep duration and socioeconomic status. Thirty-seven high school students (mean age: 18.16 ± 0.44 years) attending the same school type, i.e. 'liceo scientifico' (science-based high school), were enrolled. Students' self-reported weight and height were used to calculate BMI. Participants wore an actigraph to objectively assess the quality and duration of sleep. School performance was assessed through the actual grade obtained at the final school-leaving exam, in which higher grades indicate higher performance. BMI, get-up time, mean motor activity, wake after sleep onset and number of awakenings were negatively correlated with the grade, while sleep efficiency was positively correlated. When performing a multiple regression analysis, BMI proved the only significant (negative) predictor of grade. When controlling for sleep quality, sleep duration and socioeconomic status, a higher BMI is associated with a poorer school performance in high school students. © 2015 World Obesity Federation.

  20. Penning trap mass spectrometry Q-value determinations for highly forbidden β-decays

    Science.gov (United States)

    Sandler, Rachel; Bollen, Georg; Eibach, Martin; Gamage, Nadeesha; Gulyuz, Kerim; Hamaker, Alec; Izzo, Chris; Kandegedara, Rathnayake; Redshaw, Matt; Ringle, Ryan; Valverde, Adrian; Yandow, Isaac; Low Energy Beam Ion Trap Team

    2017-09-01

    Over the last several decades, extremely sensitive, ultra-low background beta and gamma detection techniques have been developed. These techniques have enabled the observation of very rare processes, such as highly forbidden beta decays e.g. of 113Cd, 50V and 138La. Half-life measurements of highly forbidden beta decays provide a testing ground for theoretical nuclear models, and the comparison of calculated and measured energy spectra could enable a determination of the values of the weak coupling constants. Precision Q-value measurements also allow for systematic tests of the beta-particle detection techniques. We will present the results and current status of Q value determinations for highly forbidden beta decays. The Q values, the mass difference between parent and daughter nuclides, are measured using the high precision Penning trap mass spectrometer LEBIT at the National Superconducting Cyclotron Laboratory.

  1. Higher-order relationship between eigen-value separation and static flux tilts

    International Nuclear Information System (INIS)

    Beckner, W.D.

    1975-01-01

    Spatial kinetics phenomena in nuclear reactors, such as xenon-induced spatial flux oscillations, are currently being analyzed using the higher harmonic solutions to the static reactor balance equation. An important parameter in such an analysis is a global quantity called eigenvalue separation. It is desirable to be able to experimentally measure this parameter in power reactors in order to confirm design calculations. Since spatial distortions in the flux shape depend on the eigenvalue separation of the reactor, an attempt has been made previously to use this fact as a means of measuring the parameter. It was postulated that an induced flux distortion or ''static flux tilt'' could be measured and theoretically related to eigenvalue separation. Unfortunately, the behavior of experimental data did not exactly agree with theoretical predictions, and values of the parameter found using the original static flux tilt technique were consistently low. The theory has been re-evaluated here and the previously observed discrepancy eliminated. Techniques have been also developed to allow for more accurate interpretation of experimental data. In order to make the method applicable to real systems, the theory has been extended to two spatial dimensions; extension to three dimensions follows directly. Possible trouble areas have been investigated, and experimental procedures for use of the technique to measure the eigenvalue separation in power reactors are presented

  2. Polyharmonic boundary value problems positivity preserving and nonlinear higher order elliptic equations in bounded domains

    CERN Document Server

    Gazzola, Filippo; Sweers, Guido

    2010-01-01

    This monograph covers higher order linear and nonlinear elliptic boundary value problems in bounded domains, mainly with the biharmonic or poly-harmonic operator as leading principal part. Underlying models and, in particular, the role of different boundary conditions are explained in detail. As for linear problems, after a brief summary of the existence theory and Lp and Schauder estimates, the focus is on positivity or - since, in contrast to second order equations, a general form of a comparison principle does not exist - on “near positivity.” The required kernel estimates are also presented in detail. As for nonlinear problems, several techniques well-known from second order equations cannot be utilized and have to be replaced by new and different methods. Subcritical, critical and supercritical nonlinearities are discussed and various existence and nonexistence results are proved. The interplay with the positivity topic from the first part is emphasized and, moreover, a far-reaching Gidas-Ni-Nirenbe...

  3. Higher order and heavy quark mass effects in the determination of parton distribution functions

    Energy Technology Data Exchange (ETDEWEB)

    Bertone, Valerio

    2013-07-01

    The present thesis was devoted to the study of the inclusion of higher-order corrections and heavy quark mass effects in a PDF determination. This has been carried out in the NNPDF framework resulting originally in the NNPDF2.1 sets, which were at a later stage supplemented by the first LHC data leading to the most recent NNPDF2.3 sets. In Chapter 1 the concept of Parton Distribution Function (PDF) was introduced. We have shown how the analytical computation of the Deep-Inelastic-Scattering (DIS) process at order α{sub s} in QCD leads to initial-stale collinear divergences which, using the factorization theorem, can be reabsorbed into the PDFs. The energy dependence of PDFs is fully determined and the task is then reduced to the determination of the x (Bjorken variable) dependence. In Chapter 2 a detailed discussion of the factorization schemes presently available to include heavy quark mass effects into DIS structure functions has been given. It emerged that there are two possible basic approaches to the calculation of the DIS structure functions. In the first approach, the so-called Fixed-Flavour-Number Scheme (FFNS), the calculation is performed retaining the quark mass of the heavy flavours which provide a ''natural'' regulator for the infrared divergences. In the second approach, called Zero-Mass Variable-Flavour-Number Scheme (ZM-VFNS), the heavy quark masses are instead set to zero and this gives rise to the usual final-state collinear divergences that are absorbed into the PDFs. In addition, in the ZM-VFNS, the number of active flavours is assumed to increase by one unity as the energy of the process crosses the energy threshold of a given heavy quark. In order to obtain a factorization scheme that is accurate both at large and low energies, several prescriptions that interpolate between FFNS at low energy and ZM-VFNS at large energy have been proposed and implemented in as many PDF fits. In Chapter 2 they have been described showing how they behave for

  4. Higher order and heavy quark mass effects in the determination of parton distribution functions

    Energy Technology Data Exchange (ETDEWEB)

    Bertone, Valerio

    2013-07-01

    The present thesis was devoted to the study of the inclusion of higher-order corrections and heavy quark mass effects in a PDF determination. This has been carried out in the NNPDF framework resulting originally in the NNPDF2.1 sets, which were at a later stage supplemented by the first LHC data leading to the most recent NNPDF2.3 sets. In Chapter 1 the concept of Parton Distribution Function (PDF) was introduced. We have shown how the analytical computation of the Deep-Inelastic-Scattering (DIS) process at order α{sub s} in QCD leads to initial-stale collinear divergences which, using the factorization theorem, can be reabsorbed into the PDFs. The energy dependence of PDFs is fully determined and the task is then reduced to the determination of the x (Bjorken variable) dependence. In Chapter 2 a detailed discussion of the factorization schemes presently available to include heavy quark mass effects into DIS structure functions has been given. It emerged that there are two possible basic approaches to the calculation of the DIS structure functions. In the first approach, the so-called Fixed-Flavour-Number Scheme (FFNS), the calculation is performed retaining the quark mass of the heavy flavours which provide a ''natural'' regulator for the infrared divergences. In the second approach, called Zero-Mass Variable-Flavour-Number Scheme (ZM-VFNS), the heavy quark masses are instead set to zero and this gives rise to the usual final-state collinear divergences that are absorbed into the PDFs. In addition, in the ZM-VFNS, the number of active flavours is assumed to increase by one unity as the energy of the process crosses the energy threshold of a given heavy quark. In order to obtain a factorization scheme that is accurate both at large and low energies, several prescriptions that interpolate between FFNS at low energy and ZM-VFNS at large energy have been proposed and implemented in as many PDF fits. In Chapter 2 they have been described showing

  5. Higher order and heavy quark mass effects in the determination of parton distribution functions

    International Nuclear Information System (INIS)

    Bertone, Valerio

    2013-01-01

    The present thesis was devoted to the study of the inclusion of higher-order corrections and heavy quark mass effects in a PDF determination. This has been carried out in the NNPDF framework resulting originally in the NNPDF2.1 sets, which were at a later stage supplemented by the first LHC data leading to the most recent NNPDF2.3 sets. In Chapter 1 the concept of Parton Distribution Function (PDF) was introduced. We have shown how the analytical computation of the Deep-Inelastic-Scattering (DIS) process at order α s in QCD leads to initial-stale collinear divergences which, using the factorization theorem, can be reabsorbed into the PDFs. The energy dependence of PDFs is fully determined and the task is then reduced to the determination of the x (Bjorken variable) dependence. In Chapter 2 a detailed discussion of the factorization schemes presently available to include heavy quark mass effects into DIS structure functions has been given. It emerged that there are two possible basic approaches to the calculation of the DIS structure functions. In the first approach, the so-called Fixed-Flavour-Number Scheme (FFNS), the calculation is performed retaining the quark mass of the heavy flavours which provide a ''natural'' regulator for the infrared divergences. In the second approach, called Zero-Mass Variable-Flavour-Number Scheme (ZM-VFNS), the heavy quark masses are instead set to zero and this gives rise to the usual final-state collinear divergences that are absorbed into the PDFs. In addition, in the ZM-VFNS, the number of active flavours is assumed to increase by one unity as the energy of the process crosses the energy threshold of a given heavy quark. In order to obtain a factorization scheme that is accurate both at large and low energies, several prescriptions that interpolate between FFNS at low energy and ZM-VFNS at large energy have been proposed and implemented in as many PDF fits. In Chapter 2 they have been described showing how

  6. Shear-wave elastography quantitative assessment of the male breast: added value to distinguish benign and malignant palpable masses.

    Science.gov (United States)

    Crombé, Amandine; Hurtevent-Labrot, Gabrielle; Asad-Syed, Maryam; Palussière, Jean; MacGrogan, Gaetan; Kind, Michèle; Ferron, Stéphane

    2018-02-01

    To evaluate the ability of shear-wave elastography (SWE) to distinguish between benign and malignant palpable masses of the adult male breast. Clinical examination, mammography, B-mode and Doppler ultrasound findings and SWE quantitative parameters were compared in 50 benign lesions (including 40 gynaecomastias) and 15 malignant lesions (invasive ductal carcinomas) from 65 patients who were consecutively addressed for specialized advice at our comprehensive cancer centre. Mean elasticity (El mean), maximum elasticity (El max), El mean of the surrounding fatty tissue and lesion to fat ratio (El ratio) were reported for each patient. Malignant masses displayed significantly higher El mean (p masses without overlap of values between the two groups. By adding SWE to clinical examination, mammography and ultrasound, all the lesions would have been retrospectively correctly diagnosed as benign or malignant. One false positive could have been downstaged, 14/65 undetermined masses could have been correctly reclassified as 4 malignant and 10 benign lesions, for which biopsies could have consequently been avoided. Evaluation of male breast palpable masses by SWE demonstrates that malignant masses are significantly stiffer lesions and may improve diagnostic management when clinical examination, mammography and conventional ultrasound are doubtful. Advances in knowledge: Quantitative SWE is feasible in male breast and could be of great interest to help classify doubtful lesions after classical clinical and radiological evaluations, probably because of different anatomy and different tumours epidemiology compared with female breast.

  7. Affordability Challenges to Value-Based Pricing: Mass Diseases, Orphan Diseases, and Cures.

    Science.gov (United States)

    Danzon, Patricia M

    2018-03-01

    To analyze how value-based pricing (VBP), which grounds the price paid for pharmaceuticals in their value, can manage "affordability" challenges, defined as drugs that meet cost-effectiveness thresholds but are "unaffordable" within the short-run budget. Three specific contexts are examined, drawing on recent experience. First, an effective new treatment for a chronic, progressive disease, such as hepatitis C, creates a budget spike that is transitory because initial prevalence is high, relative to current incidence. Second, "cures" that potentially provide lifetime benefits may claim abnormally high VBP prices, with high immediate budget impact potentially/partially offset by deferred cost savings. Third, although orphan drugs in principle target rare diseases, in aggregate they pose affordability concerns because of the growing number of orphan indications and increasingly high prices. For mass diseases, the transitory budget impact of treating the accumulated patient stock can be managed by stratified rollout that delays treatment of stable patients and prioritizes patients at high risk of deterioration. Delay spreads the budget impact and permits potential savings from launch of competing treatments. For cures, installment payments contingent on outcomes could align payment flows and appropriately shift risk to producers. This approach, however, entails high administrative and incentive costs, especially if applied across multiple payers in the United States. For orphan drugs, the available evidence on research and development trends and returns argues against the need for a higher VBP threshold to incentivize research and development in orphan drugs, given existing statutory benefits under orphan drug legislation. Copyright © 2018 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  8. Independent prognostic value of left ventricular mass, diastolic function, and fasting plasma glucose

    DEFF Research Database (Denmark)

    Pareek, Manan; Nielsen, Mette Lundgren; Leósdóttir, Margrét

    2016-01-01

    OBJECTIVE: To explore the independent prognostic value of left ventricular (LV) mass, diastolic function, and fasting plasma glucose (FPG) for the prediction of incident cardiac events in a random population sample. DESIGN AND METHOD: 415 women and 999 men aged 56-79 years, included between 2002...

  9. Analytical review of minimum critical mass values for selected uranium and plutonium materials

    International Nuclear Information System (INIS)

    Morman, J.A.; Henrikson, D.J.; Garcia, A.S.

    1997-01-01

    Current subcritical limits for a number of uranium and plutonium materials (metals and compounds) as given in the ANSI/ANS standards for criticality safety are based on evaluations performed in the late 1970s and early 1980s. This paper presents the results of an analytical study of the minimum critical mass values for a set of materials using current codes and standard cross section sets. This work is meant to produce a consistent set of minimum critical mass values that can form the basis for adding new materials to the single-parameter tables in ANSI/ANS-8.1. Minimum critical mass results are presented for bare and water reflected full-density spheres and for full density moist (1.5 wt-% water) as calculated with KENO-Va, MCNP4A and ONEDANT. Calculations were also performed for both dry and moist materials at one-half density. Some KENO calculations were repeated using several cross section sets to examine potential bias differences. The results of the calculations were compared to the currently accepted subcritical limits. The calculated minimum critical mass values are reasonably consistent for the three codes, and differences most likely reflect differences in the cross section sets. The results are also consistent with values given in ANSI/ANS-8.1. 3 refs., 2 tabs

  10. The value of CT in localizing primary and stomach-originated masses in the lesser sac

    International Nuclear Information System (INIS)

    Dong Peng; Wang Bin; Zhang Shizhuang; Chang Guanghui; Sun Xihe; Cheng Xin

    2007-01-01

    Objective: To investigate the normal CT manifestation of the vascular arch of the gastric lesser curvature, and to further probe the value of CT in the localization diagnosis of the primary and stomach-originated masses in the lesser sac. Methods: Contrast-enhanced CT scanning was performed in 51 normal individuals. Emphasis of image observation was focused on the CT manifestations of vascular arch of the gastric lesser curvature and the relation between the vascular arch and the gastric wall. Also contrast- enhanced CT scan was performed for seventeen cases of primary and stomach-originated masses in the lesser sac subsequently proved by surgery and pathology. Image analysis was focused on the relation between the mass and the vascular arch and its branches of the gastric lesser curvature, the shape of the mass, and the relation between the mass and the gastric wall. Results: The vascular arch of the gastric lesser curvature was clearly visualized in the fifty normal individuals. The tributaries of the vascular arch near the cardiac part, gastric corpus, and pyloric part were revealed in 42, 10 and 7 cases respectively. The vascular arch was in close contact with the gastric wall in 38 cases. Among the 17 patients, 13 cases demonstrated the obliteration of the transparent fat plane between the mass and the gastric wall. In 6 patients with stomach- originated masses, 5 patients showed the stretching of vascular arch tributaries adjacent to the masses, and no vascular arch and its tributaries could be not visualized between the masses and the stomach. In 11 patients with primary masses in the lesser sac, vascular arch were showed between the masses and the stomach in 10 cases, and no stretching of vascular arch tributaries adjacent to the masses could be showed. Conclusions: CT scan can clearly depict the normal vascular arch and its branches of the gastric lesser curvature. Based on the relation between the vascular arch and the gastric wall, the presence of fat

  11. Distributed Physical and Molecular Separations for Selective Harvest of Higher Value Wheat Straw Components Project

    Energy Technology Data Exchange (ETDEWEB)

    N/A

    2004-09-30

    Wheat straw (Triticum aestivum L.) is an abundant source of plant fiber. It is regenerated, in large quantities, every year. At present, this potentially valuable resource is greatly under-exploited. Most of the excess straw biomass (i.e., tonnage above that required for agronomic cropping system sustainability) is managed through expensive chopping/tillage operations and/or burnt in the field following harvest, resulting in air pollution and associated health problems. Potential applications for wheat straw investigated within this project include energy and composites manufacture. Other methods of straw utilization that will potentially benefit from the findings of this research project include housing and building, pulp and paper, thermal insulation, fuels, and chemicals. This project focused on components of the feedstock assembly system for supplying a higher value small grains straw residue for (1) gasification/combustion and (2) straw-thermoplastic composites. This project was an integrated effort to solve the technological, infrastructural, and economic challenges associated with using straw residue for these bioenergy and bioproducts applications. The objective of the research is to contribute to the development of a low-capital distributed harvesting and engineered storage system for upgrading wheat straw to more desirable feedstocks for combustion and for straw-plastic composites. They investigated two processes for upgrading wheat straw to a more desirable feedstock: (1) an efficient combine-based threshing system for separating the intermodal stems from the leaves, sheaths, nodes, and chaff. (2) An inexpensive biological process using white-rot fungi to improve the composition of the mechanically processed straw stems.

  12. Distributed Physical and Molecular Separations for Selective Harvest of Higher Value Wheat Straw Components Project

    Energy Technology Data Exchange (ETDEWEB)

    Hess, J.R

    2005-01-31

    Wheat straw (Triticum aestivum L.) is an abundant source of plant fiber. It is regenerated, in large quantities, every year. At present, this potentially valuable resource is greatly under-exploited. Most of the excess straw biomass (i.e., tonnage above that required for agronomic cropping system sustainability) is managed through expensive chopping/tillage operations and/or burnt in the field following harvest, resulting in air pollution and associated health problems. Potential applications for wheat straw investigated within this project include energy and composites manufacture. Other methods of straw utilization that will potentially benefit from the findings of this research project include housing and building, pulp and paper, thermal insulation, fuels, and chemicals. This project focused on components of the feedstock assembly system for supplying a higher value small grains straw residue for (1) gasification/combustion and (2) straw-thermoplastic composites. This project was an integrated effort to solve the technological, infrastructural, and economic challenges associated with using straw residue for these bioenergy and bioproducts applications. The objective of the research is to contribute to the development of a low-capital distributed harvesting and engineered storage system for upgrading wheat straw to more desirable feedstocks for combustion and for straw-plastic composites. We investigated two processes for upgrading wheat straw to a more desirable feedstock: (1) An efficient combine-based threshing system for separating the internodal stems from the leaves, sheaths, nodes, and chaff. (2) An inexpensive biological process using white-rot fungi to improve the composition of the mechanically processed straw stems.

  13. Cardiorespiratory fitness and body mass index values in 9-year-old rural Norwegian children

    DEFF Research Database (Denmark)

    Resaland, G K; Mamen, A; Anderssen, S A

    2009-01-01

    AIM: To describe cardiorespiratory fitness and body mass index (BMI) values in a representative population of 9-year-old Norwegian children in two rural communities and compare present values with previous findings. METHODS: Two hundred and fifty-nine 9-year-old children were invited, and 256......, children's BMI values seem to have increased substantially. This increase is most pronounced in girls. When assessing these differences using the PI, this increase is less marked. Comparing maximal oxygen uptake data with that in earlier Nordic studies, there is no evidence that fitness has declined among...... 9-year olds. However, the limitations of the few earlier studies make reliable comparisons difficult....

  14. Higher body mass index is associated with episodic memory deficits in young adults.

    Science.gov (United States)

    Cheke, Lucy G; Simons, Jon S; Clayton, Nicola S

    2016-11-01

    Obesity has become an international health crisis. There is accumulating evidence that excess bodyweight is associated with changes to the structure and function of the brain and with a number of cognitive deficits. In particular, research suggests that obesity is associated with hippocampal and frontal lobe dysfunction, which would be predicted to impact memory. However, evidence for such memory impairment is currently limited. We hypothesised that higher body mass index (BMI) would be associated with reduced performance on a test of episodic memory that assesses not only content, but also context and feature integration. A total of 50 participants aged 18-35 years, with BMIs ranging from 18 to 51, were tested on a novel what-where-when style episodic memory test: the "Treasure-Hunt Task". This test requires recollection of object, location, and temporal order information within the same paradigm, as well as testing the ability to integrate these features into a single event recollection. Higher BMI was associated with significantly lower performance on the what-where-when (WWW) memory task and all individual elements: object identification, location memory, and temporal order memory. After controlling for age, sex, and years in education, the effect of BMI on the individual what, where, and when tasks remained, while the WWW dropped below significance. This finding of episodic memory deficits in obesity is of concern given the emerging evidence for a role for episodic cognition in appetite regulation.

  15. Exposure to violence in childhood is associated with higher body mass index in adolescence.

    Science.gov (United States)

    Gooding, Holly C; Milliren, Carly; Austin, S Bryn; Sheridan, Margaret A; McLaughlin, Katie A

    2015-12-01

    To determine whether different types of childhood adversity are associated with body mass index (BMI) in adolescence, we studied 147 adolescents aged 13-17 years, 41% of whom reported exposure to at least one adversity (maltreatment, abuse, peer victimization, or witness to community or domestic violence). We examined associations between adversity type and age- and sex-specific BMI z-scores using linear regression and overweight and obese status using logistic regression. We adjusted for potential socio-demographic, behavioral, and psychological confounders and tested for effect modification by gender. Adolescents with a history of sexual abuse, emotional abuse, or peer victimization did not have significantly different BMI z-scores than those without exposure (p>0.05 for all comparisons). BMI z-scores were higher in adolescents who had experienced physical abuse (β=0.50, 95% CI 0.12-0.91) or witnessed domestic violence (β=0.85, 95% CI 0.30-1.40). Participants who witnessed domestic violence had almost 6 times the odds of being overweight or obese (95% CI: 1.09-30.7), even after adjustment for potential confounders. No gender-by-adversity interactions were found. Exposure to violence in childhood is associated with higher adolescent BMI. This finding highlights the importance of screening for violence in pediatric practice and providing obesity prevention counseling for youth. Copyright © 2015 Elsevier Ltd. All rights reserved.

  16. Age- and gender-dependent values of skeletal muscle mass in healthy children and adolescents

    OpenAIRE

    Webber, Colin E.; Barr, Ronald D.

    2011-01-01

    Background Skeletal muscle mass (SMM) can be extracted from whole-body scans obtained by X-ray-based dual-photon absorptiometry (DXA). There is a need to establish expected age-dependent values for children and adolescents. Methods Appendicular lean tissue mass (ALM) was extracted from whole-body DXA scans in 140 healthy children and adolescents (68 females and 72 males). Whole-body SMM was calculated from ALM using equations developed by Kim et al. (Am J Clin Nutr 84:1014–1020, 2006). Age-de...

  17. Analysis of the Value Creation in Higher Institutions: A Relational Perspective

    Directory of Open Access Journals (Sweden)

    Raquel SÁNCHEZ-FERNÁNDEZ

    2010-10-01

    Full Text Available Despite the growing interest in value creation, a review of the relevant educational literature reveals that there is no generally accepted and empirically confirmed relational model of the student value creation process. This paper contributes in this way, analyzing several antecedents and consequences in the value creation process between graduates and their universities. We therefore study the effects of the quality of the student-professor interaction, trust, and university image on student perceived value. Moreover, we analyze the impact of perceived value on student satisfaction and loyalty. An empirical study was carried out in order to test the proposed theoretical model. The findings provide relevant academic and managerial implications for strategic decisionmaking at universities.

  18. Value of radio density determined by enhanced computed tomography for the differential diagnosis of lung masses

    International Nuclear Information System (INIS)

    Xie, Min

    2011-01-01

    Lung masses are often difficult to differentiate when their clinical symptoms and shapes or densities on computed tomography images are similar. However, with different pathological contents, they may appear differently on plain and enhanced computed tomography. Objectives: To determine the value of enhanced computed tomography for the differential diagnosis of lung masses based on the differences in radio density with and without enhancement. Patients and Methods: Thirty-six patients with lung cancer, 36 with pulmonary tuberculosis and 10 with inflammatory lung pseudo tumors diagnosed by computed tomography and confirmed by pathology in our hospital were selected. The mean ±SD radio densities of lung masses in the three groups of patients were calculated based on the results of plain and enhanced computed tomography. Results: There were no significant differences in the radio densities of the masses detected by plain computed tomography among patients with inflammatory lung pseudo tumors, tuberculosis and lung cancer (P> 0.05). However, there were significant differences (P< 0.01)between all the groups in terms of radio densities of masses detected by enhanced computed tomography. Conclusions: The radio densities of lung masses detected by enhanced computed tomography could potentially be used to differentiate between lung cancer, pulmonary tuberculosis and inflammatory lung pseudo tumors.

  19. Dynamics of Russian business culture values in the reflection of mass media

    Directory of Open Access Journals (Sweden)

    E. A. Sverdlikova

    2016-01-01

    Full Text Available The article analyses practices of “Traditions and values of Russian business culture” course teaching at Lomonosov Moscow State University’s Faculty of Sociology. The experience allows drawing methodological and theoretical conclusions on the values of business culture which underlie models of the modern business behavior. The first part of the publication concerns analysis of tradition of studying Russian culture values, in the paradigm of which the Russian business culture exists. According to the findings, traditions are enrooted in the Orthodoxy and are determined by patrimonial memories and contradictions of the Russian people’s character, ideals and spiritual framework. A system of Russian business values is developed based on the traditions as well as literary heritage, biographies of famous Russian and Soviet economists and set of rules of ethics code of the pre-revolutionary Russian business class. The main elements of the system include the following values: faith, family, commitment to business, patriotism, natural ingenuity, ability to set and solve atask of extra complexity, original forms of labor organization, and prevalence of moral motivation forms over material ones. The second part of the article deals with succession of the above-mentioned values in the modern Russian business environment. The content analysis is applied to examine the continuity. The object of the research is the text corpus of the Russian business press. The findings of the research show dynamics of the Russian mass media attention to the business culture values for the period from 2010 to 2014. The mass media interest to the issue coverage has been on the constant rise: from 37,2% of the aggregate amount of information on the Russian business in 2012 to 39,8% in 2014. There have also been examined dynamics of mass media attention to certain business culture values. The mass media assignedtop priority in 2012, 2013 and 2014 to the following values

  20. Formation of Tolerance in Students of Classical Higher Schools with Values of Physical Education

    Directory of Open Access Journals (Sweden)

    A A Budarnikov

    2014-12-01

    Full Text Available The paper presents the current status and problems of physical education in the classical higher school, developing the idea of orienteering sports and recreation activities in higher school towards the formation of tolerance in students with the help of physical education.

  1. Leveraging Service Blueprinting to Rethink Higher Education: When Students Become "Valued Customers," Everybody Wins

    Science.gov (United States)

    Ostrom, Amy L.; Bitner, Mary Jo; Burkhard, Kevin A.

    2011-01-01

    There is much discussion today about the need to transform higher education. Experts and researchers list numerous challenges: low student retention and graduation rates, the increasing cost of higher education, and concerns that graduates don't possess the skills required to compete successfully in today's interconnected, global marketplace.…

  2. Why neoliberal values of self-enhancement lead to cheating in higher education: a motivational account.

    Science.gov (United States)

    Pulfrey, Caroline; Butera, Fabrizio

    2013-11-01

    The significant number of financial and academic frauds hitting the headlines is paralleled by high rates of cheating in schools. Does adherence to the neoliberal values that underpin our economic and academic systems predict acceptance of cheating? Four studies revealed that adherence to neoliberal values of self-enhancement-power and achievement-predicts the motivation to gain social approval; this motivation, in turn, favors the adoption of context-specific competitive performance-approach goals, which predict the condoning of cheating. An experimental study showed that when participants were exposed to a source promoting the values of universalism and benevolence (self-transcendence values, the normative opposite of self-enhancement values), self-enhancement adherence ceased to predict the condoning of cheating. Most important, a classroom-based study addressed the core question of cheating behavior, revealing that adherence to self-enhancement values indeed predicted actual cheating behavior. These results point to the relevance of diagnosing societal values as social causes of cheating.

  3. Complex-mass shell renormalization of the higher-derivative electrodynamics

    Energy Technology Data Exchange (ETDEWEB)

    Turcati, Rodrigo [SISSA, Trieste (Italy); INFN, Sezione di Trieste, Trieste (Italy); Universidade Federal do Espirito Santo, Departamento de Fisica e Quimica, Vitoria, ES (Brazil); Laboratorio de Fisica Experimental (LAFEX), Centro Brasileiro de Pesquisas Fisicas (CBPF), Rio de Janeiro (Brazil); Neves, Mario Junior [Universidade Federal Rural do Rio de Janeiro, Departamento de Fisica, Rio de Janeiro (Brazil)

    2016-08-15

    We consider a higher-derivative extension of QED modified by the addition of a gauge-invariant dimension-6 kinetic operator in the U(1) gauge sector. The Feynman diagrams at one-loop level are then computed. The modification in the spin-1 sector leads the electron self-energy and vertex corrections diagrams finite in the ultraviolet regime. Indeed, no regularization prescription is used to calculate these diagrams because the modified propagator always occurs coupled to conserved currents. Moreover, besides the usual massless pole in the spin-1 sector, there is the emergence of a massive one, which becomes complex when computing the radiative corrections at one-loop order. This imaginary part defines the finite decay width of the massive mode. To check consistency, we also derive the decay length using the electron-positron elastic scattering and show that both results are equivalent. Because the presence of this unstable mode, the standard renormalization procedures cannot be used and is necessary adopt an appropriate framework to perform the perturbative renormalization. For this purpose, we apply the complex-mass shell scheme (CMS) to renormalize the aforementioned model. As an application of the formalism developed, we estimate a quantum bound on the massive parameter using the measurement of the electron anomalous magnetic moment and compute the Uehling potential. At the end, the renormalization group is analyzed. (orig.)

  4. Sharpening the Theater Engagement Plan (TEP) Focus: The Impact of Higher Order Beliefs and Values

    National Research Council Canada - National Science Library

    Smith, S

    2002-01-01

    .... The very existence of the debate suggests, however, that differences abound, the most fundamental of which are the world views, values, and beliefs that have been molded across the generations...

  5. Building Collegiate E-Loyalty: The Role of Perceived Value in the Quality-Loyalty Linkage in Online Higher Education

    Science.gov (United States)

    Kilburn, Brandon; Kilburn, Ashley; Davis, Dexter

    2016-01-01

    E-service quality of online higher education reflects the student's perception of quality of online exchanges across four dimensions: fulfillment, efficiency, system availability and privacy. This study links e-service quality to intentions to remain loyal as mediated by perceived value in an online higher education environment. AMOS is used to…

  6. Value and Anisotropy of the Electron and Hole Mass in Pure Wurtzite InP Nanowires.

    Science.gov (United States)

    Tedeschi, D; De Luca, M; Granados Del Águila, A; Gao, Q; Ambrosio, G; Capizzi, M; Tan, H H; Christianen, P C M; Jagadish, C; Polimeni, A

    2016-10-12

    The effective mass of electrons and holes in semiconductors is pivotal in determining the dynamics of carriers and their confinement energy in nanostructured materials. Surprisingly, this quantity is still unknown in wurtzite (WZ) nanowires (NWs) made of III-V compounds (e.g., GaAs, InAs, GaP, InP), where the WZ phase has no bulk counterpart. Here, we investigate the magneto-optical properties of InP WZ NWs grown by selective-area epitaxy that provides perfectly ordered NWs featuring high-crystalline quality. The combined analysis of the energy of free exciton states and impurity levels under magnetic field (B up to 29 T) allows us to disentangle the dynamics of oppositely charged carriers from the Coulomb interaction and thus to determine the values of the electron and hole effective mass. By application of B⃗ along different crystallographic directions, we also assess the dependence of the transport properties with respect to the NW growth axis (namely, the WZ ĉ axis). The effective mass of electrons along ĉ is m e ∥ = (0.078 ± 0.002) m 0 (m 0 is the electron mass in vacuum) and perpendicular to ĉ is m e ⊥ = (0.093 ± 0.001) m 0 , resulting in a 20% mass anisotropy. Holes exhibit a much larger (∼320%) and opposite mass anisotropy with their effective mass along and perpendicular to ĉ equal to m h ∥ = (0.81 ± 0.18) m 0 and m h ⊥ = (0.250 ± 0.016) m 0 , respectively. While no full consensus is found with current theoretical results on WZ InP, our findings show trends remarkably similar to the experimental data available in WZ bulk materials, such as InN, GaN, and ZnO.

  7. The Berlin Principles on Ranking Higher Education Institutions: Limitations, Legitimacy, and Value Conflict

    Science.gov (United States)

    Barron, Gary R. S.

    2017-01-01

    University rankings have been widely criticized and examined in terms of the environment they create for universities. In this paper, I reverse the question by examining how ranking organizations have responded to criticisms. I contrast ranking values and evaluation with those practiced by academic communities. I argue that the business of ranking…

  8. Co-Creating Curriculum in Higher Education: Promoting Democratic Values and a Multidimensional View on Learning

    Science.gov (United States)

    Bergmark, Ulrika; Westman, Susanne

    2016-01-01

    This paper discusses a case study in teacher education in Sweden, focusing on creating spaces for student engagement through co-creating curriculum. It highlights democratic values and a multidimensional learning view as underpinning such endeavors. The main findings are that co-creating curriculum is an ambiguous process entailing unpredictable,…

  9. Social Equity and the Assemblage of Values in Australian Higher Education

    Science.gov (United States)

    Rizvi, Fazal; Lingard, Bob

    2011-01-01

    The paper argues that the policy concept of social equity cannot be adequately understood in a generalised abstract manner, but is better viewed as an assemblage that brings together a number of contrasting, and sometimes competing, values. Our use of assemblage is somewhat eclectic and is designed to underscore the performative character of…

  10. Uniqueness in some higher order elliptic boundary value problems in n dimensional domains

    Directory of Open Access Journals (Sweden)

    C.-P. Danet

    2011-07-01

    Full Text Available We develop maximum principles for several P functions which are defined on solutions to equations of fourth and sixth order (including a equation which arises in plate theory and bending of cylindrical shells. As a consequence, we obtain uniqueness results for fourth and sixth order boundary value problems in arbitrary n dimensional domains.

  11. Usefulness of percentage enhancement washout value calculated on unenhanced, contrast-enhanced, and delayed enhanced CT in adrenal masses: adenoma versus metastasis

    International Nuclear Information System (INIS)

    Sohn, Kyung Myung; Lee, Sung Yong; Lee, Keun Ho

    2003-01-01

    To determine the usefulness of percentage enhancement washout value calculated on unenhanced, enhanced and delayed enhanced CT scans for the characterization of adrenal masses. Forty adrenal masses less than 5 cm in size were assessed using a protocol consisting of unenhanced CT, enhanced CT 60 seconds after intravenous administration of contrast material, and delayed enhanced CT at 10 minutes. The CT attenuation value of adrenal tumors was estimated on each scan, and percentage enhancement washout value was calculated as follows:[(attenuation value at enhanced CT-attenuation value at delayed CT)/ (attenuation value at enhanced CT-attenuation value at unenhanced CT)x100]. An adrenal mass was considered benign if its percentage enhancement washout value was at the threshold value, set to 60% and 50%, or higher. The accuracy of the procedure was determined by comparing its findings with the final clinical diagnosis. Twenty-nine massess were benign and 11 were malignant. The mean percentage enhancement washout value of the former was significantly higher than that of the latter (66.7% vs. 21.8%; p<0.01). All adenomas except one had a washout value of more than 50%. With a percentage washout threshold of 60%, 35 of 40 lesions were correctly characterized as benign or malignant [sensitivity 82.7% (24/29), specificity 100% (11/11), accuracy 87.5% (35/40)]; with a threshold of 50%, 39 of 40 lesions were correctly characterized [(sensitivity 96.5% (28/29), specificity 100% (11/11), accuracy 97.5% (39/40)]. Percentage enhancement washout values are useful for characterizing an adrenal mass as benign or malignant. For characterization, a threshold value of 50% was more accurate than one of 60%

  12. Assessment for Whom: Repositioning Higher Education Assessment as an Ethical and Value-Focused Social Practice

    Science.gov (United States)

    Wall, Andrew F.; Hursh, David; Rodgers, Joseph W., III

    2014-01-01

    It is often argued that as "consumers" of higher education, students, parents and leaders need objective, comparative information generated through systematized assessment. In response, we critique this trend toward reductionist, comparative, and ostensibly objective assessments in the United States. We describe how management has…

  13. Defining the Quality of Higher Education around Ethics and Moral Values

    Science.gov (United States)

    Prisacariu, Anca; Shah, Mahsood

    2016-01-01

    The context of higher education across the world currently presents evidence of university failures. These failures are evident in areas such as governance, financial and risk management, conduct of senior leaders and quality assurance issues surrounding international education. Having this in mind, the present paper argues the need to add a new…

  14. In the Shadow of Celebrity? World-Class University Policies and Public Value in Higher Education

    NARCIS (Netherlands)

    Cremonini, Leon; Westerheijden, Donald F.; Benneworth, Paul Stephen; Dauncey, Hugh

    2014-01-01

    The growing popularity of the concept of world-class universities raises the question of whether investing in such universities is a worthwhile use of public resources. Does concentrating public resources on the most excellent universities improve the overall quality of a higher education system,

  15. Moving beyond Face Value: Re-Envisioning Higher Education Evaluation as a Generator of Professional Knowledge

    Science.gov (United States)

    Darwin, Stephen

    2012-01-01

    Conventional student-led evaluation is now an orthodox feature of the North American, UK and Australian higher education landscape. Increasingly, it is guiding major institutional decisions around educational quality, academic promotion and more recently institutional funding by government. Yet significant research around student-led evaluation…

  16. Investigating the Curriculum through Assessment Practice in Higher Education: The Value of a "Learning Cultures" Approach

    Science.gov (United States)

    James, David

    2014-01-01

    It is widely acknowledged that the curriculum and knowledge in higher education (HE) are especially visible through (and often constructed by) assessment practices. If this is the case, it matters greatly what perspectives and theoretical tools are brought to bear on the task of understanding these practices. Having briefly set out three…

  17. Opportunities for expanded and higher value utilization of No. 3A Common hardwood lumber

    Science.gov (United States)

    Brian P. Shepley; Jan Wiedenbeck; Robert L. Smith

    2004-01-01

    The percentage of low-grade material composing the annual hardwood lumber production in the United States is on the rise. As a result, finding markets for low-grade and low-value lumber has been identified as a top priority by researchers and industry associations. This research used the ROMI-RIP and ROMI-CROSS simulation programs to determine specific conditions that...

  18. Different top-down approaches to estimate measurement uncertainty of whole blood tacrolimus mass concentration values.

    Science.gov (United States)

    Rigo-Bonnin, Raül; Blanco-Font, Aurora; Canalias, Francesca

    2018-05-08

    Values of mass concentration of tacrolimus in whole blood are commonly used by the clinicians for monitoring the status of a transplant patient and for checking whether the administered dose of tacrolimus is effective. So, clinical laboratories must provide results as accurately as possible. Measurement uncertainty can allow ensuring reliability of these results. The aim of this study was to estimate measurement uncertainty of whole blood mass concentration tacrolimus values obtained by UHPLC-MS/MS using two top-down approaches: the single laboratory validation approach and the proficiency testing approach. For the single laboratory validation approach, we estimated the uncertainties associated to the intermediate imprecision (using long-term internal quality control data) and the bias (utilizing a certified reference material). Next, we combined them together with the uncertainties related to the calibrators-assigned values to obtain a combined uncertainty for, finally, to calculate the expanded uncertainty. For the proficiency testing approach, the uncertainty was estimated in a similar way that the single laboratory validation approach but considering data from internal and external quality control schemes to estimate the uncertainty related to the bias. The estimated expanded uncertainty for single laboratory validation, proficiency testing using internal and external quality control schemes were 11.8%, 13.2%, and 13.0%, respectively. After performing the two top-down approaches, we observed that their uncertainty results were quite similar. This fact would confirm that either two approaches could be used to estimate the measurement uncertainty of whole blood mass concentration tacrolimus values in clinical laboratories. Copyright © 2018 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  19. Mother and Infant Body Mass Index, Breast Milk Leptin and Their Serum Leptin Values.

    Science.gov (United States)

    Savino, Francesco; Sardo, Allegra; Rossi, Lorenza; Benetti, Stefania; Savino, Andrea; Silvestro, Leandra

    2016-06-21

    This study investigates correlations between mother and infant Body Mass Index (BMI), their serum leptin values and breast milk leptin concentration in early infancy. We determined serum leptin values in 58 healthy infants and leptin values in their mothers' breast milk, using radioimmunoassay (RIA). Infant and maternal anthropometrics were measured. Median leptin concentration was 3.9 ng/mL (interquartile range (IQR): 2.75) in infant serum, 4.27 ng/mL (IQR: 5.62) in maternal serum and 0.89 ng/mL (IQR: 1.32) in breast milk. Median maternal BMI and weight were 24 kg/m² (IQR: 4.41) and 64 kg (IQR: 15). Median infant BMI was 15.80 kg/cm² (IQR: 4.02), while average weight was 5.130 kg (IQR: 1.627). Infants serum leptin values positively correlated with infants' BMI (p = 0.001; r = 0.213) and breast milk leptin (p = 0.03; r = 0.285). Maternal serum leptin values positively correlated with maternal BMI (p = 0.000, r = 0.449) and breast milk leptin ones (p = 0.026; r = 0.322). Breast milk leptin and maternal BMI could influence infant serum leptin values. Further studies are needed to better elucidate the role of genetics and environment on infant leptin production and risk of obesity later in life.

  20. Testes mass, but not sperm length, increases with higher levels of polyandry in an ancient sex model.

    Directory of Open Access Journals (Sweden)

    David E Vrech

    Full Text Available There is strong evidence that polyandrous taxa have evolved relatively larger testes than monogamous relatives. Sperm size may either increase or decrease across species with the risk or intensity of sperm competition. Scorpions represent an ancient direct mode with spermatophore-mediated sperm transfer and are particularly well suited for studies in sperm competition. This work aims to analyze for the first time the variables affecting testes mass, ejaculate volume and sperm length, according with their levels of polyandry, in species belonging to the Neotropical family Bothriuridae. Variables influencing testes mass and sperm length were obtained by model selection analysis using corrected Akaike Information Criterion. Testes mass varied greatly among the seven species analyzed, ranging from 1.6 ± 1.1 mg in Timogenes dorbignyi to 16.3 ± 4.5 mg in Brachistosternus pentheri with an average of 8.4 ± 5.0 mg in all the species. The relationship between testes mass and body mass was not significant. Body allocation in testes mass, taken as Gonadosomatic Index, was high in Bothriurus cordubensis and Brachistosternus ferrugineus and low in Timogenes species. The best-fitting model for testes mass considered only polyandry as predictor with a positive influence. Model selection showed that body mass influenced sperm length negatively but after correcting for body mass, none of the variables analyzed explained sperm length. Both body mass and testes mass influenced spermatophore volume positively. There was a strong phylogenetic effect on the model containing testes mass. As predicted by the sperm competition theory and according to what happens in other arthropods, testes mass increased in species with higher levels of sperm competition, and influenced positively spermatophore volume, but data was not conclusive for sperm length.

  1. The Digital Revolution and Higher Education: College Presidents, Public Differ on Value of Online Learning

    Science.gov (United States)

    Parker, Kim; Lenhart, Amanda; Moore, Kathleen

    2011-01-01

    This report is based on findings from a pair of Pew Research Center surveys conducted in spring 2011. One is a telephone survey of a nationally representative sample of 2,142 adults ages 18 and older. The other is an online survey, done in association with the Chronicle of Higher Education, among the presidents of 1,055 two-year and four-year…

  2. Quality Improvement Processes in Obesity Surgery Lead to Higher Quality and Value, Lower Costs.

    Science.gov (United States)

    Brousseau, Holli; Pohl, Dieter

    2017-03-01

    In the era of changes in the evaluation of medical services and performance, the Centers for Medicare and Medicaid Services (CMS) has determined that the key components are quality, value, and clinical practice improvement (MACRA). Weight Loss Surgery, also called Bariatric or Obesity Surgery, has been at the forefront of quality improvement and quality reporting through the Center of Excellence Program since 2005. As a result, weight loss surgery is now as safe as gallbladder surgery.1 Even within this culture of quality and safety, improvements are still possible, as described in this article. [Full article available at http://rimed.org/rimedicaljournal-2017-03.asp].

  3. Standardized uptake value of FDG corrected by lean body mass measured by DEXA

    International Nuclear Information System (INIS)

    Guirao, M.A.; Sanchez, A.M.; Saravi, F.D.; Mosconi, S.; Frias, L.

    2002-01-01

    Evaluating the metabolic activity of tumor lesion sometimes becomes important to evaluate grading of malignancy, prognosis, or response to therapy. The most used measure of the metabolic activity of [18F]-Fluorodeoxiglucose (FDG) in clinical PET is the Standardized Uptake Value (SUV). It relates the activity measured by the PET scan to the injected dose of FDG divided by the body mass. This approach overestimates SUV in 'heavy' patients, as the proportion of the 'low avid of FDG' fat mass increases. For this reason, different approaches are being evaluated to obtain a more accurate SUV measure. Aims: to compare the measured lean body mass by Dual X-Ray Absorptiometry with the previous methods of correction, to assess the more independent to the body constitution. Material and Methods: FDG metabolism was studied to 15 patients of both sexes, age between 28 and 72 y.o., body weight 55 to 92 Kg. One hour after the IV injection of 0.0045mCi/Kg of FDG, a whole body emission and transmission scan was performed to each subject in a positron emission tomograph (QUEST 250, GE-UGM, USA) for over 1 hour. Body lean mass composition was measured the same or next day by DEXA (Lunar DPX-L, USA.) ROIs were drawn on brain, liver and muscle. SUVbw =[(corrected mCi/g of tissue) / (mCi injected / body weight in grams)] was calculated for each tissue, and then recalculated replacing body weight with the measured lean body mass (SUVlm), calculated lean mass (SUVlc), body mass index (SUVmi) and body surface area (SUVsa). Corrected SUVs were normalized to each SUVbw average for a comparable visualization of results. Results: obtained data was analyzed by linear regression and curve estimation for each case in all tissues with the SPSS statistical software. A positive correlation between SUVbw and subject weight was confirmed for the 3 tissues. In Muscle and liver there was no significant correlation. The liver scanning time was variable ( 90 to 123 minutes after injection). Relating liver

  4. Subset of Kappa and Lambda Germline Sequences Result in Light Chains with a Higher Molecular Mass Phenotype.

    Science.gov (United States)

    Barnidge, David R; Lundström, Susanna L; Zhang, Bo; Dasari, Surendra; Murray, David L; Zubarev, Roman A

    2015-12-04

    In our previous work, we showed that electrospray ionization of intact polyclonal kappa and lambda light chains isolated from normal serum generates two distinct, Gaussian-shaped, molecular mass distributions representing the light-chain repertoire. During the analysis of a large (>100) patient sample set, we noticed a low-intensity molecular mass distribution with a mean of approximately 24 250 Da, roughly 800 Da higher than the mean of the typical kappa molecular-mass distribution mean of 23 450 Da. We also observed distinct clones in this region that did not appear to contain any typical post-translational modifications that would account for such a large mass shift. To determine the origin of the high molecular mass clones, we performed de novo bottom-up mass spectrometry on a purified IgM monoclonal light chain that had a calculated molecular mass of 24 275.03 Da. The entire sequence of the monoclonal light chain was determined using multienzyme digestion and de novo sequence-alignment software and was found to belong to the germline allele IGKV2-30. The alignment of kappa germline sequences revealed ten IGKV2 and one IGKV4 sequences that contained additional amino acids in their CDR1 region, creating the high-molecular-mass phenotype. We also performed an alignment of lambda germline sequences, which showed additional amino acids in the CDR2 region, and the FR3 region of functional germline sequences that result in a high-molecular-mass phenotype. The work presented here illustrates the ability of mass spectrometry to provide information on the diversity of light-chain molecular mass phenotypes in circulation, which reflects the germline sequences selected by the immunoglobulin-secreting B-cell population.

  5. Rewards boost sustained attention through higher effort: A value-based decision making approach.

    Science.gov (United States)

    Massar, Stijn A A; Lim, Julian; Sasmita, Karen; Chee, Michael W L

    2016-10-01

    Maintaining sustained attention over time is an effortful process limited by finite cognitive resources. Recent theories describe the role of motivation in the allocation of such resources as a decision process: the costs of effortful performance are weighed against its gains. We examined this hypothesis by combining methods from attention research and decision neuroscience. Participants first performed a sustained attention task at different levels of reward. They then performed a reward-discounting task, measuring the subjective costs of performance. Results demonstrated that higher rewards led to improved performance (Exp 1-3), and enhanced attentional effort (i.e. pupil diameter; Exp 2 & 3). Moreover, discounting curves constructed from the choice task indicated that subjects devalued rewards that came at the cost of staying vigilant for a longer duration (Exp 1 & 2). Motivation can thus boost sustained attention through increased effort, while sustained performance is regarded as a cost against which rewards are discounted. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

  6. Investigation on the Influence of the Brand Image of Higher Educational Institutions on Satisfaction and Customer Lifetime Value

    Science.gov (United States)

    Wang, Cheng-Cai; Chen, Chin-Tsu; Chen, Chun-Fu

    2012-01-01

    This study aimed to discuss the relationships among the brand image of universities (external variables), university satisfaction (mediating variables) and customer lifetime value (internal variables). The findings can serve as a reference for higher educational institutions in strengthening their advantages and overcoming their shortcomings, as…

  7. Generalised extreme value distributions provide a natural hypothesis for the shape of seed mass distributions.

    Directory of Open Access Journals (Sweden)

    Will Edwards

    Full Text Available Among co-occurring species, values for functionally important plant traits span orders of magnitude, are uni-modal, and generally positively skewed. Such data are usually log-transformed "for normality" but no convincing mechanistic explanation for a log-normal expectation exists. Here we propose a hypothesis for the distribution of seed masses based on generalised extreme value distributions (GEVs, a class of probability distributions used in climatology to characterise the impact of event magnitudes and frequencies; events that impose strong directional selection on biological traits. In tests involving datasets from 34 locations across the globe, GEVs described log10 seed mass distributions as well or better than conventional normalising statistics in 79% of cases, and revealed a systematic tendency for an overabundance of small seed sizes associated with low latitudes. GEVs characterise disturbance events experienced in a location to which individual species' life histories could respond, providing a natural, biological explanation for trait expression that is lacking from all previous hypotheses attempting to describe trait distributions in multispecies assemblages. We suggest that GEVs could provide a mechanistic explanation for plant trait distributions and potentially link biology and climatology under a single paradigm.

  8. The Impact of Mass and Universal Higher Education on Curriculum and Instruction: Case Studies of China and Japan

    Science.gov (United States)

    Huang, Futao

    2017-01-01

    Based on case studies of China and Japan, this study undertakes comparative research on major aspects of university curriculum and instruction-teaching activities of academics, their role in curriculum development, and their perceptions of these activities--between a mass and a universal higher education system. Major findings from the APA…

  9. Fostering Citizenship in China's Move from Elite to Mass Higher Education: An Analysis of Students' Political Socialization and Civic Participation

    Science.gov (United States)

    Li, Jun

    2009-01-01

    This study examines the patterns and interplay of college students' political orientations and socialization toward citizenship and civil society in the Chinese sociopolitical context, alongside China's move to mass higher education. Data were collected from a nationwide survey conducted in 12 Chinese universities in 2007. The analytic framework…

  10. Age- and gender-dependent values of skeletal muscle mass in healthy children and adolescents.

    Science.gov (United States)

    Webber, Colin E; Barr, Ronald D

    2012-03-01

    Skeletal muscle mass (SMM) can be extracted from whole-body scans obtained by X-ray-based dual-photon absorptiometry (DXA). There is a need to establish expected age-dependent values for children and adolescents. Appendicular lean tissue mass (ALM) was extracted from whole-body DXA scans in 140 healthy children and adolescents (68 females and 72 males). Whole-body SMM was calculated from ALM using equations developed by Kim et al. (Am J Clin Nutr 84:1014-1020, 2006). Age-dependent patterns of increase in SMM were derived by fitting SMM values to equations that consisted of the sum of two logistic expressions, one accounting for SMM changes during growth and the other for SMM changes during puberty. Normal ranges were defined so that 95% of the SMM values were included. The reproducibility of SMM measurements was obtained from whole-body DXA scans repeated on three occasions in each of a separate group of 32 normal children with repositioning between scans. Normal ranges are presented as equations describing the age-dependent pattern of increase in SMM as well as population standard deviations that increased steadily with age. For 15 children below age 10, SMM reproducibility (95% CI) was 149 g (119-199 g) while for 17 children and adolescents over age 10, reproducibility was 170 g (138-223 g). DXA-based measurements of SMM in children and adolescents are reproducible and can be expressed in terms of age-dependent Z scores.

  11. Work values and career anchors: the perspective of students of higher education in classroom methods and distance

    Directory of Open Access Journals (Sweden)

    Tais de Andrade

    2018-01-01

    Full Text Available This study takes into account the factors that interfere with career decisions from the internal demands of individuals, represented by the work values. Investigated university students’ perspective on work values and career anchors. For this, we used a survey along the 958 undergraduate students of face and distance higher education institutions in the interior of Rio Grande do Sul. The data collection instrument was developed from the Work Values Scale Revised developed by Porto and Pilati (2010 and the Inventory of Career Anchors proposed by Schein (1993; 1996. As for the results, there were significant differences between the perceptions of the two methods of teaching, but the hierarchy assigned to the values and anchors in both was similar, which shows certain pattern of agreement as to the perception of importance attached to each dimension studied.

  12. Nucleon axial form factors using Nf=2 twisted mass fermions with a physical value of the pion mass

    Science.gov (United States)

    Alexandrou, C.; Constantinou, M.; Hadjiyiannakou, K.; Jansen, K.; Kallidonis, C.; Koutsou, G.; Vaquero Aviles-Casco, A.

    2017-09-01

    We present results on the nucleon axial and induced pseudoscalar form factors using an ensemble of two degenerate twisted mass clover-improved fermions with mass yielding a pion mass of mπ=130 MeV . We evaluate the isovector and the isoscalar, as well as the strange and the charm axial form factors. The disconnected contributions are evaluated using recently developed methods that include deflation of the lower eigenstates, allowing us to extract the isoscalar, strange, and charm axial form factors. We find that the disconnected quark loop contributions are nonzero and particularly large for the induced pseudoscalar form factor.

  13. Forage mass and the nutritive value of pastures mixed with forage peanut and red clover

    Directory of Open Access Journals (Sweden)

    Ricardo Lima de Azevedo Junior

    2012-04-01

    Full Text Available The objective of this research was to estimate three pasture-based systems mixed with elephantgrass + spontaneous growth species, annual ryegrass, for pasture-based system 1; elephantgrass + spontaneous growth species + forage peanut, for pasture-based system 2; and elephantgrass + spontaneous growth species + annual ryegrass + red clover, for pasture-based system 3. Elephantgrass was planted in rows 4 m apart from each other. During the cool-season, annual ryegrass was sown in the alleys between the rows of elephantgrass; forage peanut and red clover were sown in the alleys between the elephantgrass according to the respective treatment. The experimental design was totally randomized in the three treatments (pasture-based systems, two replicates (paddocks in completely split-plot time (grazing cycles. Holstein cows receiving 5.5 kg-daily complementary concentrate feed were used in the evaluation. Pre-grazing forage mass, botanical composition and stocking rate were evaluated. Samples of simulated grazing were collected to analyze organic matter (OM, neutral detergent fiber (NDF, crude protein (CP and organic matter in situ digestibility (OMISD. Nine grazing cycles were performed during the experimental period (341 days. The average dry matter values for pre-grazing and stocking rate were 3.34; 3.46; 3.79 t/ha, and 3.28; 3.34; 3.60 AU/ha for each respective pasture-based system. Similar results were observed between the pasture-based systems for OM, NDF, CP and OMISD. Considering forage mass, stocking rate and nutritive value, the pasture-based system intercropped with forage legumes presented better performance.

  14. Critical mass, rod values and reactivity coefficients for Rapsodie; Masse critique, valeur des barres et coefficients de reactivite de rapsodie

    Energy Technology Data Exchange (ETDEWEB)

    Stevens, L; Gourdon, J [Commissariat a l' Energie Atomique, Cadarache (France). Centre d' Etudes Nucleaires

    1967-07-01

    Besides a brief general description, the report contains a description and discussion of the aims, the methods used and the results of critical mass, rod worth and static reactivity coefficient measurements on the Rapsodie reactor. (authors) [French] Apres une breve description generale, le rapport decrit et discute le but, les methodes employees et les resultats des mesures de masse critique, de reactivite des barres et des coefficients de reactivite statiques du reacteur RAPSODIE. (auteurs)

  15. Detrimental Effects of Higher Body Mass Index and Smoking Habits on Menstrual Cycles in Korean Women.

    Science.gov (United States)

    Jung, An Na; Park, Ju Hwan; Kim, Jihyun; Kim, Seok Hyun; Jee, Byung Chul; Cha, Byung Heun; Sull, Jae Woong; Jun, Jin Hyun

    2017-01-01

    Alteration of menstrual cycle by individual lifestyles and unfavorable habits may cause menstrual irregularity. We aimed to investigate the relationship between lifestyle factors and menstrual irregularity in Korean women using data from the Fifth Korea National Health and Nutrition Examination Survey (KNHANES) 2010-2012. This cross-sectional study included 3779 nondiabetic Korean women aged 19-49 years who did not take any oral contraceptives or sex hormonal compounds. We examined the association of menstrual irregularity with age, body mass index (BMI), drinking experience, and smoking habits. Age, Asian BMI, marriage status, age at menarche, and smoking habits were significantly associated with menstrual cycle irregularity (p smoking habits in middle-aged women aged 30-39 years (p smoking habits in nondiabetic Korean women. Weight loss and smoking cessation should be recommended to promote women's reproductive health.

  16. Fourth meeting entitled “Visualization and Processing of Tensors and Higher Order Descriptors for Multi-Valued Data”

    CERN Document Server

    Vilanova, Anna; Burgeth, Bernhard; Visualization and Processing of Tensors and Higher Order Descriptors for Multi-Valued Data

    2014-01-01

    Arising from the fourth Dagstuhl conference entitled Visualization and Processing of Tensors and Higher Order Descriptors for Multi-Valued Data (2011), this book offers a broad and vivid view of current work in this emerging field. Topics covered range from applications of the analysis of tensor fields to research on their mathematical and analytical properties. Part I, Tensor Data Visualization, surveys techniques for visualization of tensors and tensor fields in engineering, discusses the current state of the art and challenges, and examines tensor invariants and glyph design, including an overview of common glyphs. The second Part, Representation and Processing of Higher-order Descriptors, describes a matrix representation of local phase, outlines mathematical morphological operations techniques, extended for use in vector images, and generalizes erosion to the space of diffusion weighted MRI. Part III, Higher Order Tensors and Riemannian-Finsler Geometry, offers powerful mathematical language to model and...

  17. Does higher body mass index contribute to worse asthma control in an urban population?

    Science.gov (United States)

    Clerisme-Beaty, Emmanuelle M; Karam, Sabine; Rand, Cynthia; Patino, Cecilia M; Bilderback, Andrew; Riekert, Kristin A; Okelo, Sande O.; Diette, Gregory B.

    2009-01-01

    Background Epidemiologic findings support a positive association between asthma and obesity. Objective Determine whether obesity or increasing level of body mass index (BMI) are associated with worse asthma control in an ethnically diverse urban population. Methods Cross sectional assessment of asthma control was done in asthmatics recruited from primary care offices using four different validated asthma control questionnaires: the Asthma Control and Communication Instrument (ACCI), the Asthma Control Test (ACT), the Asthma Control Questionnaire (ACQ) and the Asthma Therapy Assessment Questionnaire (ATAQ). Multiple linear regression analysis was performed to evaluate the association between obesity and increasing BMI level and asthma control. Results Of 292 subjects mean age of 47 years, the majority were women (82%) and African American (67%). There was a high prevalence of obesity with 63%, with only 15% being normal weight. The mean score from all four questionnaires showed an average sub-optimal asthma control (mean score/maximum possible score): ACCI (8.3/19), ACT (15.4/ 25), ACQ (2.1/ 6), and ATAQ (1.3/ 4). Regression analysis showed no association between obesity or increasing BMI level and asthma control using all four questionnaires. This finding persisted even after adjusting for FEV1, smoking status, race, gender, selected co-morbid illnesses, and long-term asthma controller use. Conclusion Using four validated asthma control questionnaires, we failed to find an association between obesity and asthma control in an urban population with asthma. Weight loss may not be an appropriate strategy to improve asthma control in this population. Capsule Summary Using four different validated asthma control measures, there was no association between obesity or increasing body mass index and asthma control in a largely obese urban outpatient minority population. PMID:19615731

  18. Review of clinically accessible methods to determine lean body mass for normalization of standardized uptake values

    International Nuclear Information System (INIS)

    DEVRIESE, Joke; POTTEL, Hans; BEELS, Laurence; MAES, Alex; VAN DE WIELE, Christophe; GHEYSENS, Olivier

    2016-01-01

    With the routine use of 2-deoxy-2-[ 18 F]-fluoro-D-glucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) scans, metabolic activity of tumors can be quantitatively assessed through calculation of SUVs. One possible normalization parameter for the standardized uptake value (SUV) is lean body mass (LBM), which is generally calculated through predictive equations based on height and body weight. (Semi-)direct measurements of LBM could provide more accurate results in cancer populations than predictive equations based on healthy populations. In this context, four methods to determine LBM are reviewed: bioelectrical impedance analysis, dual-energy X-ray absorptiometry. CT, and magnetic resonance imaging. These methods were selected based on clinical accessibility and are compared in terms of methodology, precision and accuracy. By assessing each method’s specific advantages and limitations, a well-considered choice of method can hopefully lead to more accurate SUVLBM values, hence more accurate quantitative assessment of 18F-FDG PET images.

  19. Higher body mass index is associated with episodic memory deficits in young adults.

    OpenAIRE

    Cheke, Lucy Gaia; Simons, Jonathan Sam; Clayton, Nicola Susan

    2015-01-01

    Obesity has become an international health crisis. There is accumulating evidence that excess bodyweight is associated with changes to the structure and function of the brain and with a number of cognitive deficits. In particular, research suggests that obesity is associated with hippocampal and frontal lobe dysfunction, which would be predicted to impact memory. However evidence for such memory impairment is currently limited. We hypothesised that higher BMI would be associated with reduced ...

  20. Decreased physical activity attributable to higher body mass index influences fibromyalgia symptoms.

    Science.gov (United States)

    Vincent, Ann; Clauw, Daniel; Oh, Terry H; Whipple, Mary O; Toussaint, Loren L

    2014-09-01

    Although previous studies report associations between increased body mass index (BMI) and fibromyalgia symptoms, there is uncertainty as to whether this relationship is driven by physical factors, psychological factors, or both. To assess these relationships in a clinical sample of patients with fibromyalgia. Cross-sectional study. Tertiary care facility. A total of 686 patients from an existing national fibromyalgia registry. Patients completed a demographic form and self-report questionnaires including the Fibromyalgia Impact Questionnaire-Revised (FIQ-R), the Medical Outcomes Study Short Form-36 (SF-36), the Brief Pain Inventory (BPI), and the 30-item Profile of Mood States (30-item POMS). FIQ-R overall impact subscale. BMI was significantly correlated with fibromyalgia impact (P BMI and fibromyalgia impact was almost fully accounted for by physical factors and not by psychological factors. Despite patient report that pain hinders physical activity, clinicians who encounter patients with fibromyalgia, particularly patients with increased BMI, should be cognizant of the need to invest time and resources to counsel patients on physical factors (ie, physical activity) that could improve the patients' symptom experience. Copyright © 2014 American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.

  1. The Value of Attenuation Correction in Hybrid Cardiac SPECT/CT on Inferior Wall According to Body Mass Index

    International Nuclear Information System (INIS)

    Tamam, Muge; Mulazimoglu, Mehmet; Edis, Nurcan; Ozpacaci, Tevfik

    2016-01-01

    The purpose of this study was to evaluate the diagnostic value of attenuation-corrected single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) on the inferior wall compared to uncorrected (NC) SPECT MPI between obese and nonobese patients. A total of 157 consecutive patients (122 males and 35 females, with median age: 57.4 ± 11 years) who underwent AC technetium 99m-methoxyisobutylisonitrile (AC Tc99m-sestamibi) SPECT MPI were included to the study. A hybrid SPECT and transmission computed tomography (CT) system was used for the diagnosis with 1-day protocol, and stress imaging was performed first. During attenuation correction (AC) processing on a Xeleris Workstation using Myovation cardiac software with ordered subset expectation maximization (OSEM), iterative reconstruction with attenuation correction (IRAC) and NC images filtered back projection (FBP) were used. For statistical purposes, P < 0.05 was considered significant. This study included 73 patients with body mass index (BMI) <30 and 84 patients with BMI ≥ 30. In patients with higher BMI, increased amount of both visual and semiquantitative attenuation of the inferior wall was detected. IRAC reconstruction corrects the diaphragm attenuation of the inferior wall better than FBP. AC with OSEM iterative reconstruction significantly improves the diagnostic value of stress-only SPECT MPI in patients with normal weight and those who are obese, but the improvements are significantly greater in obese patients. Stress-only SPECT imaging with AC provides shorter and lower radiation exposure

  2. Effect of materials mixture on the higher heating value: Case of biomass, biochar and municipal solid waste.

    Science.gov (United States)

    Boumanchar, Imane; Chhiti, Younes; M'hamdi Alaoui, Fatima Ezzahrae; El Ouinani, Amal; Sahibed-Dine, Abdelaziz; Bentiss, Fouad; Jama, Charafeddine; Bensitel, Mohammed

    2017-03-01

    The heating value describes the energy content of any fuel. In this study, this parameter was evaluated for different abundant materials in Morocco (two types of biochar, plastic, synthetic rubber, and cardboard as municipal solid waste (MSW), and various types of biomass). Before the evaluation of their higher heating value (HHV) by a calorimeter device, the thermal behavior of these materials was investigated using thermogravimetric (TGA) and Differential scanning calorimetry (DSC) analyses. The focus of this work is to evaluate the calorific value of each material alone in a first time, then to compare the experimental and theoretical HHV of their mixtures in a second time. The heating value of lignocellulosic materials was between 12.16 and 20.53MJ/kg, 27.39 for biochar 1, 32.60MJ/kg for biochar 2, 37.81 and 38.00MJ/kg for plastic and synthetic rubber respectively and 13.81MJ/kg for cardboard. A significant difference was observed between the measured and estimated HHVs of mixtures. Experimentally, results for a large variety of mixture between biomass/biochar and biomass/MSW have shown that the interaction between biomass and other compounds expressed a synergy of 2.37% for biochar 1 and 6.11% for biochar 2, 1.09% for cardboard, 5.09% for plastic and 5.01% for synthetic rubber. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. Improved prediction of higher heating value of biomass using an artificial neural network model based on proximate analysis.

    Science.gov (United States)

    Uzun, Harun; Yıldız, Zeynep; Goldfarb, Jillian L; Ceylan, Selim

    2017-06-01

    As biomass becomes more integrated into our energy feedstocks, the ability to predict its combustion enthalpies from routine data such as carbon, ash, and moisture content enables rapid decisions about utilization. The present work constructs a novel artificial neural network model with a 3-3-1 tangent sigmoid architecture to predict biomasses' higher heating values from only their proximate analyses, requiring minimal specificity as compared to models based on elemental composition. The model presented has a considerably higher correlation coefficient (0.963) and lower root mean square (0.375), mean absolute (0.328), and mean bias errors (0.010) than other models presented in the literature which, at least when applied to the present data set, tend to under-predict the combustion enthalpy. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. Age and gender specific normal values of left ventricular mass, volume and function for gradient echo magnetic resonance imaging: a cross sectional study

    Directory of Open Access Journals (Sweden)

    Allansdotter-Johnsson Ase

    2009-01-01

    Full Text Available Abstract Background Knowledge about age-specific normal values for left ventricular mass (LVM, end-diastolic volume (EDV, end-systolic volume (ESV, stroke volume (SV and ejection fraction (EF by cardiac magnetic resonance imaging (CMR is of importance to differentiate between health and disease and to assess the severity of disease. The aims of the study were to determine age and gender specific normal reference values and to explore the normal physiological variation of these parameters from adolescence to late adulthood, in a cross sectional study. Methods Gradient echo CMR was performed at 1.5 T in 96 healthy volunteers (11–81 years, 50 male. Gender-specific analysis of parameters was undertaken in both absolute values and adjusted for body surface area (BSA. Results Age and gender specific normal ranges for LV volumes, mass and function are presented from the second through the eighth decade of life. LVM, ESV and EDV rose during adolescence and declined in adulthood. SV and EF decreased with age. Compared to adult females, adult males had higher BSA-adjusted values of EDV (p = 0.006 and ESV (p Conclusion LV volumes, mass and function vary over a broad age range in healthy individuals. LV volumes and mass both rise in adolescence and decline with age. EF showed a rapid decline in adolescence compared to changes throughout adulthood. These findings demonstrate the need for age and gender specific normal ranges for clinical use.

  5. Prognostic value of body mass index in transcatheter aortic valve implantation: A "J"-shaped curve.

    Science.gov (United States)

    González-Ferreiro, Rocío; Muñoz-García, Antonio J; López-Otero, Diego; Avanzas, Pablo; Pascual, Isaac; Alonso-Briales, Juan H; Trillo-Nouche, Ramiro; Pun, Federico; Jiménez-Navarro, Manuel F; Hernández-García, José M; Morís, César; González Juanatey, José R

    2017-04-01

    We aimed to determine whether body mass index (BMI) is a prognostic indicator for long-term, all-cause mortality in patients undergoing transcatheter aortic valve implantation (TAVI). Obesity in patients with established cardiovascular disease has previously been identified as an indicator of good prognosis, a phenomenon known as the "obesity paradox". The prognostic significance of BMI in patients with severe aortic stenosis (AoS) undergoing TAVI is a matter of current debate, as published studies are scarce and their results conflicting. This is an observational, retrospective study involving 770 patients who underwent TAVI for AoS. The cohort was divided into three groups based on their BMI: normal weight (≥18.5 to value=0.036]). After adjustment by logistic EuroSCORE, being overweight was found to be an independent protective factor against mortality (HR: 0.63 [95% CI: 0.42 to 0.94], p=0.024). This was not the case for obesity (HR: 0.92 [95% CI: 0.63 to 1.35], p=0.664). We therefore describe for the first time, a "J-shaped" regression curve describing the relationship between BMI and mortality. BMI is a predictive factor of all-cause mortality in AoS patients undergoing TAVI. This relationship takes the form of a "J-shaped" curve in which overweight patients are associated with the lowest mortality rate at follow-up. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  6. Racial Discrimination and Low Household Education Predict Higher Body Mass Index in African American Youth.

    Science.gov (United States)

    Nelson, Devin S; Gerras, Julia M; McGlumphy, Kellye C; Shaver, Erika R; Gill, Amaanat K; Kanneganti, Kamala; Ajibewa, Tiwaloluwa A; Hasson, Rebecca E

    The purpose of this study was to examine the relationships between environmental factors, including household education, community violence exposure, racial discrimination, and cultural identity, and BMI in African American adolescents. A community-based sample of 198 African American youth (120 girls, 78 boys; ages 11-19 years) from Washtenaw County, Michigan, were included in this analysis. Violence exposure was assessed by using the Survey of Children's Exposure to Community Violence; racial discrimination by using the Adolescent Discrimination Distress Index; cultural identity by using the Acculturation, Habits, and Interests Multicultural Scale for Adolescents; and household education by using a seven-category variable. Measured height and body weight were used to calculate BMI. Racial discrimination was positively associated with BMI, whereas household education was inversely associated with BMI in African American adolescents (discrimination: β = 0.11 ± 0.04, p = 0.01; education: β = -1.13 ± 0.47, p = 0.02). These relationships were significant when accounting for the confounding effects of stress, activity, diet, and pubertal development. Significant gender interactions were observed with racial discrimination and low household education associated with BMI in girls only (discrimination: β = 0.16 ± 0.05, p = 0.003; education: β = -1.12 ± 0.55, p = 0.045). There were no significant relationships between culture, community violence exposure, and BMI (all p's > 0.05). Environmental factors, including racial discrimination and low household education, predicted higher BMI in African American adolescents, particularly among girls. Longitudinal studies are needed to better understand the mechanisms by which these environmental factors increase obesity risk in African American youth.

  7. The value of the apparent diffusion coefficient in MR diffusion weighted imaging for the differential diagnosis of sinonasal masses

    International Nuclear Information System (INIS)

    Wang Yongzhe; Yang Bentao; Xian Junfang; Li Jing; Chen Guangli

    2014-01-01

    Objective: To investigate the diagnostic value of apparent diffusion coefficient in the evaluation of sinonasal masses. Methods: Sixty-seven sinonasal solid masses over 1 cm in diameter confirmed by pathology were retrospectively analyzed, all patients underwent preoperative routine MRI with DWI, the ADC values were measured in ROI within the solid mass. The patients were divided into benign and malignant groups by the histopathology, according to pathological findings, the patients were further divided into the hematolymphoid tumors, the malignancy of epithelium and mesenchymal tissue, the benign tumors of epithelial and mesenchymal tissue, and vasogenic masses. ANOVA test and t test were used to compare the ADC values of different groups. The receiver operating characteristic curve (ROC) was constructed using various cut points of ADC for different parameters to confirm the diagnostic threshold value and evaluate the diagnostic efficacy. Results: All lesions were solitary. There were 22 malignant tumors, of which 6 lesions were hematolymphoid tumors and 16 lesions malignancy from epithelium and mesenchymal tissue. There were 45 benign tumors, of which 22 lesions were benign tumors from epithelium and mesenchymal tissue and 23 lesions vasogenic masses. The mean ADC value of malignant and benign masses was (0.88 ± 0.26) × 10 -3 mm 2 /s and (1.54 ± 0.41) × 10 -3 mm 2 /s respectively. There was statistically significant differences between them (t=6.897, P <0.01). The mean ADC value was(0.63 ± 0.10) × 10 -3 mm 2 /s in hematolymphoid tumors,(0.97 ±0.24) × 10 -3 mm 2 /s in malignancy from epithelium and mesenchymal tissue, (1.38 ± 0.23) × 10 -3 mm 2 /s in benign tumors from epithelium and mesenchymal tissue,(1.68 ± 0.49) × 10 -3 mm 2 /s in vasogenic masses respectively. There was statistically significant difference among all 4 groups(F=22.788, P<0.01), and the differences between any 2 groups were still statistically significant (P <0.05). The area under

  8. Management Innovations in Higher Education: A Descriptive Study of Information Technology Managers' Perceptions Regarding the Use and Value of Project Management in Institutions of Higher Education

    Science.gov (United States)

    Durbin, Michael P.

    2013-01-01

    This study examined the perspectives of IT managers working in colleges and universities regarding their use of and value for project management. Descriptive and inferential analyses were used to understand individual innovativeness, innovation characteristics of project management, and the perceived use of and value for project management best…

  9. Validation of equations and proposed reference values to estimate fat mass in Chilean university students.

    Science.gov (United States)

    Gómez Campos, Rossana; Pacheco Carrillo, Jaime; Almonacid Fierro, Alejandro; Urra Albornoz, Camilo; Cossío-Bolaños, Marco

    2018-03-01

    (i) To propose regression equations based on anthropometric measures to estimate fat mass (FM) using dual energy X-ray absorptiometry (DXA) as reference method, and (ii)to establish population reference standards for equation-derived FM. A cross-sectional study on 6,713 university students (3,354 males and 3,359 females) from Chile aged 17.0 to 27.0years. Anthropometric measures (weight, height, waist circumference) were taken in all participants. Whole body DXA was performed in 683 subjects. A total of 478 subjects were selected to develop regression equations, and 205 for their cross-validation. Data from 6,030 participants were used to develop reference standards for FM. Equations were generated using stepwise multiple regression analysis. Percentiles were developed using the LMS method. Equations for men were: (i) FM=-35,997.486 +232.285 *Weight +432.216 *CC (R 2 =0.73, SEE=4.1); (ii)FM=-37,671.303 +309.539 *Weight +66,028.109 *ICE (R2=0.76, SEE=3.8), while equations for women were: (iii)FM=-13,216.917 +461,302 *Weight+91.898 *CC (R 2 =0.70, SEE=4.6), and (iv) FM=-14,144.220 +464.061 *Weight +16,189.297 *ICE (R 2 =0.70, SEE=4.6). Percentiles proposed included p10, p50, p85, and p95. The developed equations provide valid and accurate estimation of FM in both sexes. The values obtained using the equations may be analyzed from percentiles that allow for categorizing body fat levels by age and sex. Copyright © 2017 SEEN y SED. Publicado por Elsevier España, S.L.U. All rights reserved.

  10. The diagnostic value of ultrasound-guided fine-needle aspiration biopsy in breast masses

    International Nuclear Information System (INIS)

    Lee, Nam Hee; Lim, Hyun Yang; Park, Noh Kyong; Tae, Seok; Shin, Kyung Ja; Lee, Sang Chun

    1993-01-01

    Real-time ultrasound-guided fine-needle aspiration biopsy in 137 solid breast masses was performed. Sonographic findings were categorized into three groups and aspirates were categorized into three cytologic groups. The cytologic results was reported benign masses (cytologic group 1) in 71 cases (52%). malignant masses (cytologic group 2 and 3) in 44 cases (32%) and insufficient specimens in 22 case (16%). Insufficient specimens were treated as benign masses. Excisional biopsy in 44 malignant masses and 3 benign masses according to cytologic results, clinical findings and follow up study was performed. The result was reported 41 malignant masses and 6 benign masses. Based on cytologic criteria, sensitivity for detection of malignancy was 93% and specificity was 94%. In conclusion, the high specificity provided by ultrasound-guided fine-needle aspiration biopsy could markedly reduce unnecessary surgical excisions for benign masses and it should be routinely performed, since it can give physical and emotional benefits to patients and lead to earlier and cost effective diagnosis of breast cancer

  11. The diagnostic value of ultrasound-guided fine-needle aspiration biopsy in breast masses

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Nam Hee; Lim, Hyun Yang; Park, Noh Kyong; Tae, Seok; Shin, Kyung Ja; Lee, Sang Chun [Seoul Red Cross Hospital, Seoul (Korea, Republic of)

    1993-05-15

    Real-time ultrasound-guided fine-needle aspiration biopsy in 137 solid breast masses was performed. Sonographic findings were categorized into three groups and aspirates were categorized into three cytologic groups. The cytologic results was reported benign masses (cytologic group 1) in 71 cases (52%). malignant masses (cytologic group 2 and 3) in 44 cases (32%) and insufficient specimens in 22 case (16%). Insufficient specimens were treated as benign masses. Excisional biopsy in 44 malignant masses and 3 benign masses according to cytologic results, clinical findings and follow up study was performed. The result was reported 41 malignant masses and 6 benign masses. Based on cytologic criteria, sensitivity for detection of malignancy was 93% and specificity was 94%. In conclusion, the high specificity provided by ultrasound-guided fine-needle aspiration biopsy could markedly reduce unnecessary surgical excisions for benign masses and it should be routinely performed, since it can give physical and emotional benefits to patients and lead to earlier and cost effective diagnosis of breast cancer.

  12. Mass Spectrometry Market: Value chain and stakeholder analysis up to 2024

    OpenAIRE

    Smita Deshmukh

    2016-01-01

    Transparency Market Research Reports incorporated a definite business overview and investigation inclines on "Mass Spectrometry Market". This report likewise incorporates more illumination about fundamental review of the business including definitions, requisitions and worldwide business sector industry structure. Read Full Report: http://www.transparencymarketresearch.com/mass-spectrometry-market.html

  13. Reference values of amino acids, acylcarnitines and succinylacetone by tandem mass spectrometry for use in newborn screening in southwest Colombia.

    Science.gov (United States)

    Céspedes, Nora; Valencia, Angela; Echeverry, Carlos Alberto; Arce-Plata, Maria Isabel; Colón, Cristóbal; Castiñeiras, Daisy E; Hurtado, Paula Margarita; Cocho, Jose Angel; Herrera, Sócrates; Arévalo-Herrera, Myriam

    2017-09-30

    Inborn errors of metabolism (IEM) represent an important public health problem due to current diagnosis and treatment limitations, poor life quality of affected patients, and consequent untimely child death. In contrast to classical methods, tandem mass spectrometry (MS/MS) has allowed simultaneous evaluation of multiple metabolites associated with IEM offering higher sensitivity, low false positive rates and high throughput. Determine concentration levels for amino acids and acylcarnitines in blood of newborns from Colombia, to establish reference values for further use in diagnosis of IEM. Implementation of a method to determine amino acids, acylcarnitines and succinylacetone in newborn dried blood spots using MS/MS, and its application in a cross-sectional study conducted in 891 healthy neonates from Cali and Quibdo cities is described. fifty-seven analytes that allow the diagnosis of more than 40 different pathologies were tested. The method showed to be linear, precise and accurate. Healthy neonates 1-18 days of age were included, 523 from Cali and 368 from Quibdo; 52% male and 48% female. Age-related differences on the concentration levels of amino acids and acylcarnitines were observed whereas no significant differences by gender were found. The study has contributed to reveal the usual concentration levels of amino acids, acylcarnitines and succinylacetone that could be used as reference for the establishment of a newborn metabolic screening program in Colombia.

  14. Higher Daily Energy Expenditure and Respiratory Quotient, Rather Than Fat-Free Mass, Independently Determine Greater ad Libitum Overeating.

    Science.gov (United States)

    Piaggi, Paolo; Thearle, Marie S; Krakoff, Jonathan; Votruba, Susanne B

    2015-08-01

    Body fat-free mass (FFM), energy expenditure (EE), and respiratory quotient (RQ) are known predictors of daily food intake. Because FFM largely determines EE, it is unclear whether body composition per se or the underlying metabolism drives dietary intake. The objective of the study was to test whether 24-hour measures of EE and RQ and their components influence ad libitum food intake independently of FFM. One hundred seven healthy individuals (62 males/45 females, 84 Native Americans/23 whites; age 33 ± 8 y; body mass index 33 ± 8 kg/m(2); body fat 31% ± 8%) had 24-hour measures of EE in a whole-room indirect calorimeter during energy balance, followed by 3 days of ad libitum food intake using computerized vending machine systems. Body composition was estimated by dual-energy x-ray absorptiometry. FFM, 24-hour EE, RQ, spontaneous physical activity, sleeping EE (sleeping metabolic rate), awake and fed thermogenesis, and ad libitum food intake (INTAKE) were measured. Higher 24-hour RQ (P FFM (P = .65), were independent predictors of INTAKE. Mediation analysis demonstrated that 24-hour EE is responsible for 80% of the FFM effect on INTAKE (44.5 ± 16.9 kcal ingested per kilogram of FFM, P= .01), whereas the unique effect due to solely FFM was negligible (10.6 ± 23.2, P = .65). Spontaneous physical activity (r = 0.33, P = .001), but not sleeping metabolic rate (P = .71), positively predicted INTAKE, whereas higher awake and fed thermogenesis determined greater INTAKE only in subjects with a body mass index of 29 kg/m(2) or less (r = 0.44, P = .01). EE and RQ, rather than FFM, independently determine INTAKE, suggesting that competitive energy-sensing mechanisms driven by the preferential macronutrient oxidation and total energy demands may regulate food intake.

  15. Added value of shear-wave elastography for evaluation of breast masses detected with screening US imaging.

    Science.gov (United States)

    Lee, Su Hyun; Chang, Jung Min; Kim, Won Hwa; Bae, Min Sun; Seo, Mirinae; Koo, Hye Ryoung; Chu, A Jung; Gweon, Hye Mi; Cho, Nariya; Moon, Woo Kyung

    2014-10-01

    To evaluate the additional value of shear-wave elastography (SWE) to B-mode ultrasonography (US) and to determine an appropriate guideline for the combined assessment of screening US-detected breast masses. This study was conducted with institutional review board approval, and written informed consent was obtained. From March 2010 to February 2012, B-mode US and SWE were performed in 159 US-detected breast masses before biopsy. For each lesion, Breast Imaging Reporting and Data System (BI-RADS) category on B-mode US images and the maximum stiffness color and elasticity values on SWE images were assessed. A guideline for adding SWE data to B-mode US was developed with the retrospective cohort to improve diagnostic performance in sensitivity and specificity and was validated in a distinct prospective cohort of 207 women prior to biopsy. Twenty-one of 159 masses in the development cohort and 12 of 207 breast masses in the validation cohort were malignant. In the development cohort, when BI-RADS category 4a masses showing a dark blue color or a maximum elasticity value of 30 kPa or less on SWE images were downgraded to category 3, specificity increased from 9.4% (13 of 138) to 59.4% (82 of 138) and 57.2% (79 of 138) (P breast masses. BI-RADS category 4a masses detected at US screening that showed a dark blue color or a maximum elasticity value of 30 kPa or less on SWE images can be safely followed up instead of performing biopsy. © RSNA, 2014.

  16. A scheme to calculate higher-order homogenization as applied to micro-acoustic boundary value problems

    Science.gov (United States)

    Vagh, Hardik A.; Baghai-Wadji, Alireza

    2008-12-01

    Current technological challenges in materials science and high-tech device industry require the solution of boundary value problems (BVPs) involving regions of various scales, e.g. multiple thin layers, fibre-reinforced composites, and nano/micro pores. In most cases straightforward application of standard variational techniques to BVPs of practical relevance necessarily leads to unsatisfactorily ill-conditioned analytical and/or numerical results. To remedy the computational challenges associated with sub-sectional heterogeneities various sophisticated homogenization techniques need to be employed. Homogenization refers to the systematic process of smoothing out the sub-structural heterogeneities, leading to the determination of effective constitutive coefficients. Ordinarily, homogenization involves a sophisticated averaging and asymptotic order analysis to obtain solutions. In the majority of the cases only zero-order terms are constructed due to the complexity of the processes involved. In this paper we propose a constructive scheme for obtaining homogenized solutions involving higher order terms, and thus, guaranteeing higher accuracy and greater robustness of the numerical results. We present

  17. Opportunities and Challenges in Enhancing Value of Annual Glacier Mass Balance Monitoring Examples from Western North America

    Science.gov (United States)

    Pelto, M. S.

    2017-12-01

    Alpine glacier mass balance is the most accurate indicator of glacier response to climate and with retreat of alpine glaciers is one of the clearest signals of global climate change. Completion of long term, representative and homogenous mass balance field measurement of mass balance, compiled by WGMS, is a key climate data record. To ensure a monitoring program remains vital and funded local collaboration and connecting the research to local societal impacts is crucial. Working with local partners in collecting and providing the right data is critical whether their interest is in hydropower, irrigation, municipal supply, hazard reduction and/or aquatic ecosystems. The expansion of remote sensing and modeling capability provides both a challenge to continued relevance and an opportunity for field mass balance programs to expand relevance. In modelling studies of both glacier mass balance and glacier runoff transient balance data has equivalent value with annual balance data, for both calibration runs and as an input variable. This increases the utility of mid-season field observations. Remote sensing provides repeat imagery that often identifies the AAR and transient snowline of a glacier. For runoff assessment understanding the specific percent of glacier surface area that is glacier ice, older firn, and retained snowpack from the previous winter at frequent intervals during the melt season is vital since each region has a different melt factor. A denser field observation network combined with this imagery can provide additional point balance values of ablation that complement the mass balance record. Periodic measurement of mass balance at a denser network using GPR, LIDAR, TLS or probing is required to better understand long term point balance locations and is important at end of the melt season not just beginning, and has value mid-season for modelling. Applications of each of utility of field mass balance observations will be illustrated.

  18. Mass

    International Nuclear Information System (INIS)

    Quigg, Chris

    2007-01-01

    In the classical physics we inherited from Isaac Newton, mass does not arise, it simply is. The mass of a classical object is the sum of the masses of its parts. Albert Einstein showed that the mass of a body is a measure of its energy content, inviting us to consider the origins of mass. The protons we accelerate at Fermilab are prime examples of Einsteinian matter: nearly all of their mass arises from stored energy. Missing mass led to the discovery of the noble gases, and a new form of missing mass leads us to the notion of dark matter. Starting with a brief guided tour of the meanings of mass, the colloquium will explore the multiple origins of mass. We will see how far we have come toward understanding mass, and survey the issues that guide our research today.

  19. Distinguishing benign and malignant pelvic masses : The value of different diagnostic methods in everyday clinical practice

    NARCIS (Netherlands)

    Engelen, Mirjam J. A.; Bongaerts, Alphons H. H.; Sluiter, Wim J.; De Haan, Harm H.; Bogchelman, Dick H.; TenVergert, Els M.; Willemse, Pax H. B.; van der Zee, Ate G. J.

    Objective: To optimize referral to specialized gynaecologists for surgical treatment of ovarian cancer by improving preoperative discrimination between benign and malignant pelvic tumours. Study design: In a prospective multicentre study 143 patients with a pelvic mass were included. At several

  20. From Q-value measurements to mass and structure of proton-rich nuclei in the tin region

    International Nuclear Information System (INIS)

    Grant, I.S.; Kirchner, R.; Klepper, O.; Koslowsky, V.T.; Rathke, G.E.; Roeckl, E.; Rykaczewski, K.; Schardt, D.; Larsson, P.O.; Nyman, G.; Tidemand-Petersson, P.; Zganjar, E.F.; Spanier, L.; Nolte, E.; Plochocki, A.; Zylicz, J.

    1984-01-01

    The authors have measured the electron capture decay energies for the isotopes sup(108,) sup(106,) 104 Sn, 96 Pd, and 111 Te. From these values the mass defects were derived. For 105 Sn an improved half-live of 28 + 35 was obtained. (HSI)

  1. CMR reference values for left ventricular volumes, mass, and ejection fraction using computer-aided analysis : The Framingham Heart Study

    NARCIS (Netherlands)

    Chuang, Michael L.; Gona, Philimon; Hautvast, Gilion L.T.F.; Salton, Carol J.; Breeuwer, Marcel; O'Donnell, Christopher J.; Manning, Warren J.

    Purpose To determine sex-specific reference values for left ventricular (LV) volumes, mass, and ejection fraction (EF) in healthy adults using computer-aided analysis and to examine the effect of age on LV parameters. Materials and Methods We examined data from 1494 members of the Framingham Heart

  2. Supplementing an energy adequate, higher protein diet with protein does not enhance fat-free mass restoration after short-term severe negative energy balance.

    Science.gov (United States)

    Berryman, C E; Sepowitz, J J; McClung, H L; Lieberman, H R; Farina, E K; McClung, J P; Ferrando, A A; Pasiakos, S M

    2017-06-01

    Negative energy balance during military operations can be severe and result in significant reductions in fat-free mass (FFM). Consuming supplemental high-quality protein following such military operations may accelerate restoration of FFM. Body composition (dual-energy X-ray absorptiometry) and whole body protein turnover (single-pool [ 15 N]alanine method) were determined before (PRE) and after 7 days (POST) of severe negative energy balance during military training in 63 male US Marines (means ± SD, 25 ± 3 yr, 84 ± 9 kg). After POST measures were collected, volunteers were randomized to receive higher protein (HIGH: 1,103 kcal/day, 133 g protein/day), moderate protein (MOD: 974 kcal/day, 84 g protein/day), or carbohydrate-based low protein control (CON: 1,042 kcal/day, 7 g protein/day) supplements, in addition to a self-selected, ad libitum diet, for the 27-day intervention (REFED). Measurements were repeated POST-REFED. POST total body mass (TBM; -5.8 ± 1.0 kg, -7.0%), FFM (-3.1 ± 1.6 kg, -4.7%), and net protein balance (-1.7 ± 1.1 g protein·kg -1 ·day -1 ) were lower and proteolysis (1.1 ± 1.9 g protein·kg -1 ·day -1 ) was higher compared with PRE ( P energy (4,498 ± 725 kcal/day). All volunteers, independent of group assignment, achieved positive net protein balance (0.4 ± 1.0 g protein·kg -1 ·day -1 ) and gained TBM (5.9 ± 1.7 kg, 7.8%) and FFM (3.6 ± 1.8 kg, 5.7%) POST-REFED compared with POST ( P energy-adequate, higher protein diets with additional protein may not be necessary to restore FFM after short-term severe negative energy balance. NEW & NOTEWORTHY This article demonstrates 1 ) the majority of physiological decrements incurred during military training (e.g., total and fat-free mass loss), with the exception of net protein balance, resolve and return to pretraining values after 27 days and 2 ) protein supplementation, in addition to an ad libitum, higher protein (~2.0 g·kg -1 ·day -1 ), energy adequate diet, is not necessary to

  3. The value of ultrasonography combined with compression technique in differentiation between benign and malignant breast masses

    International Nuclear Information System (INIS)

    Yoon, Seong Kuk; Lee, Ki Nam; Nam, Kyung Jin; Jung, Won Jung

    2001-01-01

    To determine whether the compression technique is a valuable additional method for differentiating between benign and malignant breast masses. The ultrasonographic findings of 95 benign and 53 malignant masses, all pathologically proven, were prospectively analyzed with regard to five diagnostic criteria: shape (regular/irregular), retrotumoral acoustic phenomena (posterior enhancement/posterior attenuation), internal echo pattern (homogeneous/inhomogeneous), compression effect on shape (distortion/no change), and compression effect on internal echo pattern (more homogeneous/no change). The number of cases of benign and malignant masses, respectively, was as follows: regular/irregular shape: 84/11, 9/44; posterior acoustic enhancement/posterior attenuation: 82/13, 16/37; homogeneous/inhomogeneous internal echo pattern: 78/17, 14/39; distortion/no change in shape: 76/19, 5/48; and more homogeneous/no change in internal echo pattern: 71/24, 3/50. For all diagnostic criteria for the differentiation of benign and malignant masses, the differences were statistically significant (p<.05). Ultrasonography is helpful for differentiating between benign and malignant breast masses. The compression technique is a valuable additional diagnostic method

  4. Inclusion of human mineralized exometabolites and fish wastes as a source of higher plant mineral nutrition in BTLSS mass exchange

    Science.gov (United States)

    Tikhomirova, Natalia; Tikhomirov, Alexander A.; Ushakova, Sofya; Anischenko, Olesya; Trifonov, Sergey V.

    Human exometabolites inclusion into an intrasystem mass exchange will allow increasing of a closure level of a biological-technical life support system (BTLSS). Previously at the IBP SB RAS it was shown that human mineralized exometabolites could be incorporated in the BTLSS mass exchange as a mineral nutrition source for higher plants. However, it is not known how that combined use of human mineralized exometabolites and fish wastes in the capacity of nutrient medium, being a part of the BTLSS consumer wastes, will affect the plant productivity. Several wheat vegetations were grown in an uneven-aged conveyor on a neutral substrate. A mixture of human mineralized exometabolites and fish wastes was used as a nutrient solution in the experiment treatment and human mineralized exometabolites were used in the control. Consequently, a high wheat yield in the experiment treatment practically equal to the control yield was obtained. Thus, mineralized fish wastes can be an additional source of macro-and micronutrients for plants, and use of such wastes for the plant mineral nutrition allows increasing of BTLSS closure level.

  5. The Perceived Value of University-Based, Continuing Education Leadership Development Programs for Administrators in Higher Education: An Intangibles Model of Value Creation

    Science.gov (United States)

    Stone, Geraldine Louise

    2012-01-01

    This study examined the perceived value of leadership development programs (LDPs) provided by continuing education for administrators in colleges and universities. Included in this study were questions about the perceived value of non-credit, credit, and blended (credit and non-credit) programs at the individual, institutional, and higher…

  6. Internal Carotid Artery Ectasia: The Value of Imaging Studies Prior to Biopsy of a Retropharyngeal Mass

    Directory of Open Access Journals (Sweden)

    Kenneth Chan

    2010-11-01

    Full Text Available The presence of retropharyngeal tissue mass often raises the suspicion of malignancy, especially in elderly patients. This prompts urgent biopsy to investigate tissue histology. We discuss a case where this is contraindicated as the retropharyngeal mass was illustrated by CT scanning and confirmed with MRI to be a tortuous coursing internal carotid artery. An awareness of this unusual anatomical variation and a careful interpretation of imaging studies both at the stage of differential diagnosis and pre-operative screening are essential to avoid damage to important structures, causing unnecessary complications.

  7. Considerations of anthropometric, tissue volume, and tissue mass scaling for improved patient specificity of skeletal S values

    International Nuclear Information System (INIS)

    Bolch, W.E.; Patton, P.W.; Shah, A.P.; Rajon, D.A.; Jokisch, D.W.

    2002-01-01

    It is generally acknowledged that reference man (70 kg in mass and 170 cm in height) does not adequately represent the stature and physical dimensions of many patients undergoing radionuclide therapy, and thus scaling of radionuclide S values is required for patient specificity. For electron and beta sources uniformly distributed within internal organs, the mean dose from self-irradiation is noted to scale inversely with organ mass, provided no escape of electron energy occurs at the organ boundaries. In the skeleton, this same scaling approach is further assumed to be correct for marrow dosimetry; nevertheless, difficulties in quantitative assessments of marrow mass in specific skeletal regions of the patient make this approach difficult to implement clinically. Instead, scaling of marrow dose is achieved using various anthropometric parameters that presumably scale in the same proportion. In this study, recently developed three-dimensional macrostructural transport models of the femoral head and humeral epiphysis in three individuals (51-year male, 82-year female, and 86-year female) are used to test the abilities of different anthropometric parameters (total body mass, body surface area, etc.) to properly scale radionuclide S values from reference man models. The radionuclides considered are 33 P, 177 Lu, 153 Sm, 186 Re, 89 Sr, 166 Ho, 32 P, 188 Re, and 90 Y localized in either the active marrow or endosteal tissues of the bone trabeculae. S value scaling is additionally conducted in which the 51-year male subject is assigned as the reference individual; scaling parameters are then expanded to include tissue volumes and masses for both active marrow and skeletal spongiosa. The study concludes that, while no single anthropometric parameter emerges as a consistent scaler of reference man S values, lean body mass is indicated as an optimal scaler when the reference S values are based on 3D transport techniques. Furthermore, very exact patient-specific scaling of

  8. Higher weight, lower education: a longitudinal association between adolescents' body mass index and their subsequent educational achievement level?

    Science.gov (United States)

    Larsen, Junilla K; Kleinjan, Marloes; Engels, Rutger C M E; Fisher, Jennifer O; Hermans, Roel C J

    2014-12-01

    The purpose of this study was to examine the association between adolescents' body mass index (BMI) z-scores and their subsequent level of schooling, extending previous longitudinal research by using objectively measured weight and height data. A longitudinal study with 3 study waves (1-year intervals) involving 1248 Dutch adolescents (49% girls; mean age = 13.7 years) at schools providing different educational levels was used to determine adolescents who moved and did not move to a lower educational level in the first year, or in the second year, and to examine whether this movement could be predicted by BMI z-scores (zBMI), after controlling for a large range of potential confounding factors. A total of 1164 Dutch adolescents continued in the same level of education, whereas 84 adolescents moved to a lower educational level (43 moved in the first and 41 in the second year). A higher zBMI significantly increased the risk of a general transition to a lower educational level, and of a transition in the first year, but not in the second year, after controlling for potential demographic, behavioral, and psychological confounds. Findings suggest that a higher zBMI during adolescence immediately lowers educational achievement level during general secondary education. © 2014, American School Health Association.

  9. Age and gender specific normal values of left ventricular mass, volume and function for gradient echo magnetic resonance imaging: a cross sectional study

    International Nuclear Information System (INIS)

    Cain, Peter A; Ahl, Ragnhild; Hedstrom, Erik; Ugander, Martin; Allansdotter-Johnsson, Ase; Friberg, Peter; Arheden, Hakan

    2009-01-01

    Knowledge about age-specific normal values for left ventricular mass (LVM), end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV) and ejection fraction (EF) by cardiac magnetic resonance imaging (CMR) is of importance to differentiate between health and disease and to assess the severity of disease. The aims of the study were to determine age and gender specific normal reference values and to explore the normal physiological variation of these parameters from adolescence to late adulthood, in a cross sectional study. Gradient echo CMR was performed at 1.5 T in 96 healthy volunteers (11–81 years, 50 male). Gender-specific analysis of parameters was undertaken in both absolute values and adjusted for body surface area (BSA). Age and gender specific normal ranges for LV volumes, mass and function are presented from the second through the eighth decade of life. LVM, ESV and EDV rose during adolescence and declined in adulthood. SV and EF decreased with age. Compared to adult females, adult males had higher BSA-adjusted values of EDV (p = 0.006) and ESV (p < 0.001), similar SV (p = 0.51) and lower EF (p = 0.014). No gender differences were seen in the youngest, 11–15 year, age range. LV volumes, mass and function vary over a broad age range in healthy individuals. LV volumes and mass both rise in adolescence and decline with age. EF showed a rapid decline in adolescence compared to changes throughout adulthood. These findings demonstrate the need for age and gender specific normal ranges for clinical use

  10. A higher-order generalized singular value decomposition for comparison of global mRNA expression from multiple organisms.

    Directory of Open Access Journals (Sweden)

    Sri Priya Ponnapalli

    Full Text Available The number of high-dimensional datasets recording multiple aspects of a single phenomenon is increasing in many areas of science, accompanied by a need for mathematical frameworks that can compare multiple large-scale matrices with different row dimensions. The only such framework to date, the generalized singular value decomposition (GSVD, is limited to two matrices. We mathematically define a higher-order GSVD (HO GSVD for N≥2 matrices D(i∈R(m(i × n, each with full column rank. Each matrix is exactly factored as D(i=U(iΣ(iV(T, where V, identical in all factorizations, is obtained from the eigensystem SV=VΛ of the arithmetic mean S of all pairwise quotients A(iA(j(-1 of the matrices A(i=D(i(TD(i, i≠j. We prove that this decomposition extends to higher orders almost all of the mathematical properties of the GSVD. The matrix S is nondefective with V and Λ real. Its eigenvalues satisfy λ(k≥1. Equality holds if and only if the corresponding eigenvector v(k is a right basis vector of equal significance in all matrices D(i and D(j, that is σ(i,k/σ(j,k=1 for all i and j, and the corresponding left basis vector u(i,k is orthogonal to all other vectors in U(i for all i. The eigenvalues λ(k=1, therefore, define the "common HO GSVD subspace." We illustrate the HO GSVD with a comparison of genome-scale cell-cycle mRNA expression from S. pombe, S. cerevisiae and human. Unlike existing algorithms, a mapping among the genes of these disparate organisms is not required. We find that the approximately common HO GSVD subspace represents the cell-cycle mRNA expression oscillations, which are similar among the datasets. Simultaneous reconstruction in the common subspace, therefore, removes the experimental artifacts, which are dissimilar, from the datasets. In the simultaneous sequence-independent classification of the genes of the three organisms in this common subspace, genes of highly conserved sequences but significantly different cell

  11. Higher mass-independent isotope fractionation of methylmercury in the pelagic food web of Lake Baikal (Russia).

    Science.gov (United States)

    Perrot, Vincent; Pastukhov, Mikhail V; Epov, Vladimir N; Husted, Søren; Donard, Olivier F X; Amouroux, David

    2012-06-05

    Mercury undergoes several transformations that influence its stable isotope composition during a number of environmental and biological processes. Measurements of Hg isotopic mass-dependent (MDF) and mass-independent fractionation (MIF) in food webs may therefore help to identify major sources and processes leading to significant bioaccumulation of methylmercury (MeHg). In this work, δ(13)C, δ(15)N, concentration of Hg species (MeHg, inorganic Hg), and stable isotopic composition of Hg were determined at different trophic levels of the remote and pristine Lake Baikal ecosystem. Muscle of seals and different fish as well as amphipods, zooplankton, and phytoplankton were specifically investigated. MDF during trophic transfer of MeHg leading to enrichment of heavier isotopes in the predators was clearly established by δ(202)Hg measurements in the pelagic prey-predator system (carnivorous sculpins and top-predator seals). Despite the low concentrations of Hg in the ecosystem, the pelagic food web reveals very high MIF Δ(199)Hg (3.15-6.65‰) in comparison to coastal fish (0.26-1.65‰) and most previous studies in aquatic organisms. Trophic transfer does not influence MIF signature since similar Δ(199)Hg was observed in sculpins (4.59 ± 0.55‰) and seal muscles (4.62 ± 0.60‰). The MIF is suggested to be mainly controlled by specific physical and biogeochemical characteristics of the water column. The higher level of MIF in pelagic fish of Lake Baikal is mainly due to the bioaccumulation of residual MeHg that is efficiently turned over and photodemethylated in deep oligotrophic and stationary (i.e., long residence time) freshwater columns.

  12. Reference absolute and indexed values for left and right ventricular volume, function and mass from cardiac computed tomography

    International Nuclear Information System (INIS)

    Stojanovska, Jadranka; Prasitdumrong, Hutsaya; Patel, Smita; Sundaram, Baskaran; Gross, Barry H.; Yilmaz, Zeynep N.; Kazerooni, Ella A.

    2014-01-01

    Left ventricular (LV) and right ventricular (RV) volumetric and functional parameters are important biomarkers for morbidity and mortality in patients with heart failure. To retrospectively determine reference mean values of LV and RV volume, function and mass normalised by age, gender and body surface area (BSA) from retrospectively electrocardiographically gated 64-slice cardiac computed tomography (CCT) by using automated analysis software in healthy adults. The study was approved by the institutional review board with a waiver of informed consent. Seventy-four healthy subjects (49% female, mean age 49.6±11) free of hypertension and hypercholesterolaemia with a normal CCT formed the study population. Analyses of LV and RV volume (end-diastolic, end-systolic and stroke volumes), function (ejection fraction), LV mass and inter-rater reproducibility were performed with commercially available analysis software capable of automated contour detection. General linear model analysis was performed to assess statistical significance by age group after adjustment for gender and BSA. Bland–Altman analysis assessed the inter-rater agreement. The reference range for LV and RV volume, function, and LV mass was normalised to age, gender and BSA. Statistically significant differences were noted between genders in both LV mass and RV volume (P-value<0.0001). Age, in concert with gender, was associated with significant differences in RV end-diastolic volume and LV ejection fraction (P-values 0.027 and 0.03). Bland–Altman analysis showed acceptable limits of agreement (±1.5% for ejection fraction) without systematic error. LV and RV volume, function and mass normalised to age, gender and BSA can be reported from CCT datasets, providing additional information important for patient management.

  13. mvp - an open-source preprocessor for cleaning duplicate records and missing values in mass spectrometry data.

    Science.gov (United States)

    Lee, Geunho; Lee, Hyun Beom; Jung, Byung Hwa; Nam, Hojung

    2017-07-01

    Mass spectrometry (MS) data are used to analyze biological phenomena based on chemical species. However, these data often contain unexpected duplicate records and missing values due to technical or biological factors. These 'dirty data' problems increase the difficulty of performing MS analyses because they lead to performance degradation when statistical or machine-learning tests are applied to the data. Thus, we have developed missing values preprocessor (mvp), an open-source software for preprocessing data that might include duplicate records and missing values. mvp uses the property of MS data in which identical chemical species present the same or similar values for key identifiers, such as the mass-to-charge ratio and intensity signal, and forms cliques via graph theory to process dirty data. We evaluated the validity of the mvp process via quantitative and qualitative analyses and compared the results from a statistical test that analyzed the original and mvp-applied data. This analysis showed that using mvp reduces problems associated with duplicate records and missing values. We also examined the effects of using unprocessed data in statistical tests and examined the improved statistical test results obtained with data preprocessed using mvp.

  14. Preliminary Modelling of Mass Flux at the Surface of Plant Leaves within the MELiSSA Higher Plant Compartments

    Science.gov (United States)

    Holmberg, Madeleine; Paille, Christel; Lasseur, Christophe

    The ESA project Micro Ecological Life Support System Alternative (MELiSSA) is an ecosystem of micro-organisms and higher plants, constructed with the objective of being operated as a tool to understand artificial ecosystems to be used for a long-term or permanent manned planetary base (e.g. Moon or Mars). The purpose of such a system is to provide for generation of food, water recycling, atmospheric regeneration and waste management within defined standards of quality and reliability. As MELiSSA consists of individual compartments which are connected to each other, the robustness of the system is fully dependent on the control of each compartment, as well as the flow management between them. Quality of consumables and reliability of the ecosystem rely on the knowledge, understanding and control of each of the components. This includes the full understanding of all processes related to the higher plants. To progress in that direction, this paper focuses on the mechanical processes driving the gas and liquid exchanges between the plant leaf and its environment. The process responsible for the mass transfer on the surface of plant leaves is diffusion. The diffusion flux is dependent on the behaviour of the stoma of the leaf and also on the leaf boundary layer (BL). In this paper, the physiology of the leaf is briefly examined in order to relate parameters such as light quality, light quantity, CO2 concentration, temperature, leaf water potential, humidity, vapour pressure deficit (VPD) gradients and pollutants to the opening or closing of stomata. The diffusion process is described theoretically and the description is compared to empirical approaches. The variables of the BL are examined and the effect airflow in the compartment has on the BL is investigated. Also presented is the impact changes in different environmental parameters may have on the fluid exchanges. Finally, some tests, to evaluate the accuracy of the concluded model, are suggested.

  15. Higher than expected NOx emission from trucks may affect attainability of NO2 limit values in the Netherlands

    NARCIS (Netherlands)

    Velders, G.J.M.; Geilenkirchen, G.P.; Lange, R. de

    2011-01-01

    In past years, the European limit value for average annual NO2 concentration has been exceeded in city streets and along motorways in the Netherlands. By 2015 the limit value must be adhered to in the Netherlands. Although the total road length for which exceedance is likely is expected to decrease

  16. Sufficient condition for existence of solutions for higher-order resonance boundary value problem with one-dimensional p-Laplacian

    Directory of Open Access Journals (Sweden)

    Liu Yang

    2007-10-01

    Full Text Available By using coincidence degree theory of Mawhin, existence results for some higher order resonance multipoint boundary value problems with one dimensional p-Laplacian operator are obtained.

  17. The Role of Trust in Creating Value and Student Loyalty in Relational Exchanges between Higher Education Institutions and Their Students

    Science.gov (United States)

    Carvalho, Sergio W.; de Oliveira Mota, Marcio

    2010-01-01

    The globalization of educational services and the increasing competition coming from the private sector have forced higher education institutions to market their programs more aggressively and to look at student loyalty as the key for future success. Student loyalty to higher education institutions represents not only a more stable financial basis…

  18. Prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma

    International Nuclear Information System (INIS)

    Li, Zhao-Qu; Zou, Lan; Liu, Tian-Run; Yang, An-Kui

    2015-01-01

    Patients with head and neck cancer often suffer from malnutrition. This study aims to investigate the influence of body mass index (BMI) on the prognosis of laryngeal squamous cell carcinoma (LSCC). A total of 473 patients with LSCC initially treated at Sun Yat-sen University Cancer Center between January 2005 and July 2009 were retrospectively reviewed. Survival analysis was performed by the Kaplan-Meier method and Cox regression model. Low BMI before treatment was significantly associated with poor overall survival in patients with LSCC (P<0.001). BMI was an independent prognostic factor for patients with LSCC. Leanness before treatment was associated with poor prognosis in patients with LSCC. Good nutritional status is favorable to improve survival in patients with LSCC

  19. Situational Methodology as Multifaceted Pedagogical Tool of Influence on the Formation of Socio-Ethical Values of Future Managers-Economists in Higher Schools of Ukraine and Germany

    Science.gov (United States)

    Sikaliuk, Anzhela

    2014-01-01

    The role and importance of situational methodology as one of the pedagogical tools of influence on the formation of socio-ethical values of future managers in higher schools of Ukraine and Germany have been theoretically substantiated. The possibilities of situational methodology influence on the formation of socio-ethical values of…

  20. Personal values, social capital and higher education student career decidedness: a new ‘protean’ informed model

    OpenAIRE

    Fearon, C.; Nachmias, S.; McLaughlin, H.; Jackson, S.

    2016-01-01

    This study investigates the role of personal values as motivational antecedents for understanding HE student career decidedness among university business school (UBS) students. We propose a new ‘protean’ informed HE student career decidedness model for theorizing how both personal values and social capital mediators (student social capital; personal, social and enterprise skills; access to resources) help in the student-centric and self-directed processes of career decision-making. A mixed me...

  1. Value of shear wave arrival time contour display in shear wave elastography for breast masses diagnosis.

    Science.gov (United States)

    Zhou, Bang-Guo; Wang, Dan; Ren, Wei-Wei; Li, Xiao-Long; He, Ya-Ping; Liu, Bo-Ji; Wang, Qiao; Chen, Shi-Gao; Alizad, Azra; Xu, Hui-Xiong

    2017-08-01

    To evaluate the diagnostic performance of shear wave arrival time contour (SWATC) display for the diagnosis of breast lesions and to identify factors associated with the quality of shear wave propagation (QSWP) in breast lesions. This study included 277 pathologically confirmed breast lesions. Conventional B-mode ultrasound characteristics and shear wave elastography parameters were computed. Using the SWATC display, the QSWP of each lesion was assigned to a two-point scale: score 1 (low quality) and score 2 (high quality). Binary logistic regression analysis was performed to identify factors associated with QSWP. The area under the receiver operating characteristic curve (AUROC) for QSWP to differentiate benign from malignant lesions was 0.913, with a sensitivity of 91.9%, a specificity of 90.7%, a positive predictive value (PPV) of 74.0%, and a negative predictive value (NPV) of 97.5%. Compared with using the standard deviation of shear wave speed (SWS SD ) alone, SWS SD combined with QSWP increased the sensitivity from 75.8% to 93.5%, but decreased the specificity from 95.8% to 89.3% (P breast lesions.

  2. Observations of borehole deformation modulus values before and after extensive heating of a granitic rock mass

    International Nuclear Information System (INIS)

    Patrick, W.C.; Yow, J.L.; Caxelrod, M.C.

    1985-01-01

    An extensive campaign of in situ deformation modulus measurements was recently completed using a standard NX borehole jack. These results were obtained in a granite intrusive where spent nuclear-fuel assemblies and electrical heaters had raised the rock temperatures 10 0 C to 40 0 C above ambient. We present an analysis of temperature effects based on 41 preheat and 63 post-heat measurements in three boreholes. Using analysis of covariance statistical techniques, we found that the deformation modulus is affected by heat, loading direction, and position within the borehole. The analysis also uncovered a significant interaction between the effects of heating and loading direction. We used 123 measurements from the same boreholes to evaluate the ''Draft Standard Guide for Estimating the In Situ Modulus of Rock Masses Using the NX-Borehole Jack'' which was recently proposed by Heuze. In particular, we examined the criterion for screening measurements in those cases where contact between the jack platen and the borehole wall was incomplete. We found that the proposed screen appears to operate randomly on the data and is therefore ineffective

  3. Higher body mass index may induce asthma among adolescents with pre-asthmatic symptoms: a prospective cohort study

    Directory of Open Access Journals (Sweden)

    Myers Leann

    2011-07-01

    Full Text Available Abstract Background Limited studies have prospectively examined the role of body mass index (BMI as a major risk factor for asthma during adolescence. This study investigates whether BMI is associated with increased risk of developing physician-diagnosed asthma during 12-month follow-up among adolescents with undiagnosed asthma-like symptoms at baseline. Methods A total of 4,052 adolescents with undiagnosed asthma-like symptoms at baseline were re-examined after a 12-month follow-up. Asthma cases were considered confirmed only after diagnosis by a physician based on the New England core and International Study of Asthma and Allergies in Childhood (ISAAC criteria video questionnaires, and accompanying pulmonary function tests. Logistic regression analyses were used to evaluate the relationship of BMI and the risk of acquiring asthma. Results The results indicated that girls with higher BMI were at an increased risk of developing asthma during the 12-month follow-up. The odds ratios for girls developing physician-diagnosed asthma were 1.75 (95% CI = 1.18-2.61 and 1.12 (95% CI = 0.76-1.67, respectively, for overweight and obesity as compared to the normal weight reference group after adjustment for other covariates. A similar relationship was not observed for overweight and obese boys who were also significantly more active than their female counterparts. Conclusions Increased BMI exaggerates the risk of acquiring asthma in symptomatic adolescent females but not in adolescent males. Thus, gender is an important modifier of BMI-related asthma risk. Additional research will be required to determine whether the increased asthma risk results from genetic, physiological or behavioural differences.

  4. The calculation of the chemical exergies of coal-based fuels by using the higher heating values

    International Nuclear Information System (INIS)

    Bilgen, Selcuk; Kaygusuz, Kamil

    2008-01-01

    This paper demonstrates the application of exergy to gain a better understanding of coal properties, especially chemical exergy and specific chemical exergy. In this study, a BASIC computer program was used to calculation of the chemical exergies of the coal-based fuels. Calculations showed that the chemical composition of the coal influences strongly the values of the chemical exergy. The exergy value of a coal is closely related to the H:C and O:C ratios. High proportions of hydrogen and/or oxygen, compared to carbon, generally reduce the exergy value of the coal. High contents of the moisture and/or the ash cause to low values of the chemical exergy. The aim of this paper is to calculate the chemical exergy of coals by using equations given in the literature and to detect and to evaluate quantitatively the effect of irreversible phenomena increased the thermodynamic imperfection of the processes. In this paper, the calculated exergy values of the fuels will be useful for energy experts studied in the coal mining area and coal-fired powerplants

  5. Existence of Positive Solutions for a Coupled System of (p, q-Laplacian Fractional Higher Order Boundary Value Problems

    Directory of Open Access Journals (Sweden)

    K.R. Prasad

    2015-11-01

    Full Text Available In this paper, we establish the existence of at least three positive solutions for a system of (p,q-Laplacian fractional order two-point boundary value problems by applying five functionals fixed point theorem under suitable conditions on a cone in a Banach space.

  6. News at Nine: The value of near-real time data for reaching mass media

    Science.gov (United States)

    Allen, J.; Ward, K.; Simmon, R. B.; Carlowicz, M. J.; Scott, M.; Przyborski, P. D.; Voiland, A. P.

    2012-12-01

    NASA's Earth Observatory (EO) is an online publication featuring NASA Earth science news and images. Since its inception in 1999, the EO team has relied heavily on near-real time satellite data to publish imagery of breaking news events, such as volcanoes, floods, fires, and dust storms. Major news outlets (Associated Press, The Weather Channel, CNN, etc.) have regularly republished Earth Observatory imagery in their coverage of events. Because of the nature of modern 24-hour news cycle, media almost always want near-real time coverage; providing it depends heavily on rapid data turnaround, user-friendly data systems, and fast data access. We will discuss how we use near-real time data and provide examples of how data systems have been transformed in the past 13 years. We will offer some thoughts on best practices (from the view of a user) in expedited data systems and the positive effect of those practices on public awareness of our content.. Finally, we will share how we work with science teams to see the potential stories in their data and the value of providing the data in a timely fashionAcquired October 9, 2010, this natural-color image shows the toxic sludge spill from an alumina plant in southern Hungary.

  7. Consumption Values and Empowerment of the Student as Customer: Taking a Rational Look inside Higher Education's "Pandora's Box"

    Science.gov (United States)

    van Andel, Jeroen; Botas, Paulo Charles Pimentel; Huisman, Jeroen

    2012-01-01

    There has been much debate on the concept of student as customer/consumer in higher education but little empirical research, most of which lacks a solid theoretical framework. This article summarises the key arguments in the literature and their shortcomings, proposes a framework to analyse student perceptions and behaviour, and reports research…

  8. Between Instrumental and Developmental Learning: Ambivalence in Student Values and Identity Positions in Marketized UK Higher Education

    Science.gov (United States)

    Tomlinson, Michael

    2015-01-01

    The move towards a market-driven HE system in the UK and active policy promotion of students as consumers has generated much commentary on the ways in which students' expectations and experiences have been transformed. This article introduces and develops a conceptualization of contemporary higher students' views of their relationship to higher…

  9. Organizational Integration Strategies for Promoting Enduring Donor Relations in Higher Education: The Value of Building Inner Circle Network Relationships

    Science.gov (United States)

    Chung-Hoon, Tanise L.; Hite, Julie M.; Hite, Steven J.

    2007-01-01

    Successful fund-raising efforts are critical for public higher education institutions as they seek to offset uncertainty in government funding. This study evaluated the enhancement of fund-raising capacity through the maintenance of enduring donor relationships. Utilizing the Donor/Organization Integration Model, the study examined interactions…

  10. Mei Symmetry and New Conserved Quantities of Tzénoff Equations for the Variable Mass Higher-Order Nonholonomic System

    International Nuclear Information System (INIS)

    Zheng Shi-Wang; Wang Jian-Bo; Chen Xiang-Wei; Xie Jia-Fang

    2012-01-01

    Operational systems of spacecraft are general variable mass mechanics systems, and their symmetries and conserved quantities imply profound physical rules of the space system. We study the Mei symmetry of Tzénoff equations for a variable mass nonholonomic system and the new conserved quantities derived. The function expression of the new conserved quantities and the criterion equation which deduces these conserved quantities are presented. This result has some theoretical values in further research of conservation laws obeyed by the variable mass system. (general)

  11. Lean body mass-based standardized uptake value, derived from a predictive equation, might be misleading in PET studies

    International Nuclear Information System (INIS)

    Erselcan, Taner; Turgut, Bulent; Dogan, Derya; Ozdemir, Semra

    2002-01-01

    The standardized uptake value (SUV) has gained recognition in recent years as a semiquantitative evaluation parameter in positron emission tomography (PET) studies. However, there is as yet no consensus on the way in which this index should be determined. One of the confusing factors is the normalisation procedure. Among the proposed anthropometric parameters for normalisation is lean body mass (LBM); LBM has been determined by using a predictive equation in most if not all of the studies. In the present study, we assessed the degree of agreement of various LBM predictive equations with a reference method. Secondly, we evaluated the impact of predicted LBM values on a hypothetical value of 2.5 SUV, normalised to LBM (SUV LBM ), by using various equations. The study population consisted of 153 women, aged 32.3±11.8 years (mean±SD), with a height of 1.61±0.06 m, a weight of 71.1±17.5 kg, a body surface area of 1.77±0.22 m 2 and a body mass index of 27.6±6.9 kg/m 2 . LBM (44.2±6.6 kg) was measured by a dual-energy X-ray absorptiometry (DEXA) method. A total of nine equations from the literature were evaluated, four of them from recent PET studies. Although there was significant correlation between predicted and measured LBM values, 95% limits of agreement determined by the Bland and Altman method showed a wide range of variation in predicted LBM values as compared with DEXA, no matter which predictive equation was used. Moreover, only one predictive equation was not statistically different in the comparison of means (DEXA and predicted LBM values). It was also shown that the predictive equations used in this study yield a wide range of SUV LBM values from 1.78 to 5.16 (29% less or 107% more) for an SUV of 2.5. In conclusion, this study suggests that estimation of LBM by use of a predictive equation may cause substantial error for an individual, and that if LBM is chosen for the SUV normalisation procedure, it should be measured, not predicted. (orig.)

  12. Evaluation of The Value of Core Needle Biopsy in The Diagnosis of a Breast Mass

    Directory of Open Access Journals (Sweden)

    Asieh Sadat Fattahi

    2016-06-01

    Full Text Available Background: Core needle biopsy (CNB with histological findings is regarded as one of the most important diagnostic measures that make preoperative assessment and planning for appropriate treatment possible. The aim of this study was to determine the sensitivity and specificity of core biopsy results in our patients with benign and malignant breast lumps, especially for borderline breast lesions, by using a classification method.Methods: In this study, 116 patients who were referred to the Surgery Clinic of Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran with breast lump and underwent diagnostic procedures such as mammography and ultrasound were selected. Core needle biopsy (Tru-cut #14 or 16 was performed. After that, excisional biopsy was done. The benign, malignant and unspecified samples obtained by core needle biopsy were evaluated with the samples of the surgical and pathological findings. Then, false positive, false negative, sensitivity, specificity, and diagnostic accuracy of the core needle biopsy method were calculated. Also, the National Health Service Breast Screening Program (NHSBSP classification was employed.Results: The mean age of the participants in this study was 39±13.13 years and the mean tumor size was 2.7 cm. An average of 3.35 biopsies was taken from all patients. Most of the pathology samples taken from CNB and excisional biopsy were compatible with invasive ductal carcinoma. Of the B type classifications, B5 was the most frequent in both methods. Borderline lesions B3 and B4 had a change in their category after surgery. About 2.5% of the samples in core biopsy were inadequate. Skin bruising was the most common core biopsy complication reported. While, the most common complication of excisional biopsy was hematoma. Accuracy, sensitivity, specificity, positive and negative predictive values of the core needle biopsy procedure compared with excisional biopsy was 95.5%, 92.6%, 100%, 100%, and 91

  13. An application of a relational database system for high-throughput prediction of elemental compositions from accurate mass values.

    Science.gov (United States)

    Sakurai, Nozomu; Ara, Takeshi; Kanaya, Shigehiko; Nakamura, Yukiko; Iijima, Yoko; Enomoto, Mitsuo; Motegi, Takeshi; Aoki, Koh; Suzuki, Hideyuki; Shibata, Daisuke

    2013-01-15

    High-accuracy mass values detected by high-resolution mass spectrometry analysis enable prediction of elemental compositions, and thus are used for metabolite annotations in metabolomic studies. Here, we report an application of a relational database to significantly improve the rate of elemental composition predictions. By searching a database of pre-calculated elemental compositions with fixed kinds and numbers of atoms, the approach eliminates redundant evaluations of the same formula that occur in repeated calculations with other tools. When our approach is compared with HR2, which is one of the fastest tools available, our database search times were at least 109 times shorter than those of HR2. When a solid-state drive (SSD) was applied, the search time was 488 times shorter at 5 ppm mass tolerance and 1833 times at 0.1 ppm. Even if the search by HR2 was performed with 8 threads in a high-spec Windows 7 PC, the database search times were at least 26 and 115 times shorter without and with the SSD. These improvements were enhanced in a low spec Windows XP PC. We constructed a web service 'MFSearcher' to query the database in a RESTful manner. Available for free at http://webs2.kazusa.or.jp/mfsearcher. The web service is implemented in Java, MySQL, Apache and Tomcat, with all major browsers supported. sakurai@kazusa.or.jp Supplementary data are available at Bioinformatics online.

  14. Gamma-ray mass attenuation coefficient and half value layer factor of some oxide glass shielding materials

    International Nuclear Information System (INIS)

    Waly, El-Sayed A.; Fusco, Michael A.; Bourham, Mohamed A.

    2016-01-01

    The variation in dosimetric parameters such as mass attenuation coefficient, half value layer factor, exposure buildup factor, and the photon mean free path for different oxide glasses for the incident gamma energy range 0.015–15 MeV has been studied using MicroShield code. It has been inferred that the addition of PbO and Bi 2 O 3 improves the gamma ray shielding properties. Thus, the effect of chemical composition on these parameters is investigated in the form of six different glass compositions, which are compared with specialty concrete for nuclear radiation shielding. The composition termed ‘Glass 6’ in this paper has the highest mass attenuation and the smallest half value layer and may have potential applications in radiation shielding. An example dry storage cask utilizing an additional layer of Glass 6 as an intermediate shielding layer, simulated in MicroShield, is capable of reducing the exposure rate at the cask surface by over 20 orders of magnitude compared to the case without a glass layer. Based on this study, Glass 6 shows promise as a gamma-ray shielding material, particularly for dry cask storage.

  15. Development of a tool for prediction of ovarian cancer in patients with adnexal masses: Value of plasma fibrinogen.

    Directory of Open Access Journals (Sweden)

    Veronika Seebacher

    Full Text Available To develop a tool for individualized risk estimation of presence of cancer in women with adnexal masses, and to assess the added value of plasma fibrinogen.We performed a retrospective analysis of a prospectively maintained database of 906 patients with adnexal masses who underwent cystectomy or oophorectomy. Uni- and multivariate logistic regression analyses including pre-operative plasma fibrinogen levels and established predictors were performed. A nomogram was generated to predict the probability of ovarian cancer. Internal validation with split-sample analysis was performed. Decision curve analysis (DCA was then used to evaluate the clinical net benefit of the prediction model.Ovarian cancer including borderline tumours was found in 241 (26.6% patients. In multivariate analysis, elevated plasma fibrinogen, elevated CA-125, suspicion for malignancy on ultrasound, and postmenopausal status were associated with ovarian cancer and formed the basis for the nomogram. The overall predictive accuracy of the model, as measured by AUC, was 0.91 (95% CI 0.87-0.94. DCA revealed a net benefit for using this model for predicting ovarian cancer presence compared to a strategy of treat all or treat none.We confirmed the value of plasma fibrinogen as a strong predictor for ovarian cancer in a large cohort of patients with adnexal masses. We developed a highly accurate multivariable model to help in the clinical decision-making regarding the presence of ovarian cancer. This model provided net benefit for a wide range of threshold probabilities. External validation is needed before a recommendation for its use in routine practice can be given.

  16. Higher Thyroid-Stimulating Hormone, Triiodothyronine and Thyroxine Values Are Associated with Better Outcome in Acute Liver Failure.

    Science.gov (United States)

    Anastasiou, Olympia; Sydor, Svenja; Sowa, Jan-Peter; Manka, Paul; Katsounas, Antonios; Syn, Wing-Kin; Führer, Dagmar; Gieseler, Robert K; Bechmann, Lars P; Gerken, Guido; Moeller, Lars C; Canbay, Ali

    2015-01-01

    Changes in thyroid hormone levels, mostly as non-thyroidal illness syndrome (NTIS), have been described in many diseases. However, the relationship between acute liver failure (ALF) and thyroid hormone levels has not yet been clarified. The present study evaluates potential correlations of select thyroid functional parameters with ALF. 84 consecutively recruited ALF patients were grouped according to the outcome of ALF (spontaneous recovery: SR; transplantation or death: NSR). TSH, free thyroxine (fT4), free triiodothyronine (fT3), T4, and T3 were determined. More than 50% of patients with ALF presented with abnormal thyroid parameters. These patients had greater risk for an adverse outcome than euthyroid patients. SR patients had significantly higher TSH, T4, and T3 concentrations than NSR patients. Albumin concentrations were significantly higher in SR than in NSR. In vitro T3 treatment was not able to rescue primary human hepatocytes from acetaminophen induced changes in mRNA expression. In patients with ALF, TSH and total thyroid hormone levels differed significantly between SR patients and NSR patients. This might be related to diminished liver-derived transport proteins, such as albumin, in more severe forms of ALF. Thyroid parameters may serve as additional indicators of ALF severity.

  17. Prediction of outcome of bright light treatment in patients with seasonal affective disorder: Discarding the early response, confirming a higher atypical balance, and uncovering a higher body mass index at baseline as predictors of endpoint outcome.

    Science.gov (United States)

    Dimitrova, Tzvetelina D; Reeves, Gloria M; Snitker, Soren; Lapidus, Manana; Sleemi, Aamar R; Balis, Theodora G; Manalai, Partam; Tariq, Muhammad M; Cabassa, Johanna A; Karim, Naila N; Johnson, Mary A; Langenberg, Patricia; Rohan, Kelly J; Miller, Michael; Stiller, John W; Postolache, Teodor T

    2017-11-01

    We tested the hypothesis that the early improvement in mood after the first hour of bright light treatment compared to control dim-red light would predict the outcome at six weeks of bright light treatment for depressed mood in patients with Seasonal Affective Disorder (SAD). We also analyzed the value of Body Mass Index (BMI) and atypical symptoms of depression at baseline in predicting treatment outcome. Seventy-eight adult participants were enrolled. The first treatment was controlled crossover, with randomized order, and included one hour of active bright light treatment and one hour of control dim-red light, with one-hour washout. Depression was measured on the Structured Interview Guide for the Hamilton Rating Scale for Depression-SAD version (SIGH-SAD). The predictive association of depression scores changes after the first session. BMI and atypical score balance with treatment outcomes at endpoint were assessed using multivariable linear and logistic regressions. No significant prediction by changes in depression scores after the first session was found. However, higher atypical balance scores and BMI positively predicted treatment outcome. Absence of a control intervention for the six-weeks of treatment (only the first session in the laboratory was controlled). Exclusion of patients with comorbid substance abuse, suicidality and bipolar I disorder, and patients on antidepressant medications, reducing the generalizability of the study. Prediction of outcome by early response to light treatment was not replicated, and the previously reported prediction of baseline atypical balance was confirmed. BMI, a parameter routinely calculated in primary care, was identified as a novel predictor, and calls for replication and then exploration of possible mediating mechanisms. Published by Elsevier B.V.

  18. Five features of value-based insurance design plans were associated with higher rates of medication adherence.

    Science.gov (United States)

    Choudhry, Niteesh K; Fischer, Michael A; Smith, Benjamin F; Brill, Gregory; Girdish, Charmaine; Matlin, Olga S; Brennan, Troyen A; Avorn, Jerry; Shrank, William H

    2014-03-01

    Value-based insurance design (VBID) plans selectively lower cost sharing to increase medication adherence. Existing plans have been structured in a variety of ways, and these variations could influence the effectiveness of VBID plans. We evaluated seventy-six plans introduced by a large pharmacy benefit manager during 2007-10. We found that after we adjusted for the other features and baseline trends, VBID plans that were more generous, targeted high-risk patients, offered wellness programs, did not offer disease management programs, and made the benefit available only for medication ordered by mail had a significantly greater impact on adherence than plans without these features. The effects were as large as 4-5 percentage points. These findings can provide guidance for the structure of future VBID plans.

  19. Mei Symmetry and New Conserved Quantities of Tzénoff Equations for the Variable Mass Higher-Order Nonholonomic System

    Institute of Scientific and Technical Information of China (English)

    ZHENG Shi-Wang; WANG Jian-Bo; CHEN Xiang-Wei; XIE Jia-Fang

    2012-01-01

    Operational systems of spacecraft are general variable mass mechanics systems,and their symmetries and conserved quantities imply profound physical rules of the space system.We study the Mei symmetry of Tzénoff equations for a variable mass nonholonomic system and the new conserved quantities derived.The function expression of the new conserved quantities and the criterion equation which deduces these conserved quantities are presented.This result has some theoretical values in further research of conservation laws obeyed by the variable mass system.%Operational systems of spacecraft are general variable mass mechanics systems, and their symmetries and conserved quantities imply profound physical rules of the space system. We study the Mei symmetry of Tzenoff equations for a variable mass nonholonomic system and the new conserved quantities derived. The function expression of the new conserved quantities and the criterion equation which deduces these conserved quantities are presented. This result has some theoretical values in further research of conservation laws obeyed by the variable mass system.

  20. In folio study of carbonic anhydrase and Rubisco activities in higher C3 plants using 18O and mass spectrometry

    International Nuclear Information System (INIS)

    Peltier, G.; Despax, V.; Dimon, B.; Rumeau, D.; Tourneux, C.

    1994-01-01

    This document studies the effects of a mild water stress and carbonic anhydrase activity by ethoxyzolamide (EZA) on the diffusion of CO 2 in leaves, by 18 O labelling of O 2 and of CO 2 associated to mass spectrometry. (A.B.). 5 refs., 2 figs

  1. Diagnostic I-131 scintigraphy in patients with differentiated thyroid cancer. No additional value of higher scan dose

    International Nuclear Information System (INIS)

    Phan, T.T.H.; Tol, K.M. van; Links, T.P.; Piers, D.A.; Vries, E.G.E. de; Dullaart, R.P.F.; Jager, P.L.

    2004-01-01

    After initial treatment with total thyroidectomy and radio iodine ablation, most follow-up protocols for patients with differentiated thyroid carcinoma contain cyclic diagnostic I-131 imaging and serum thyroglobulin (Tg) measurements. The applied diagnostic I-131 doses vary between 37 and 370 MBq. The aim of this study was to determine the yield of a diagnostic scan with 370 MBq I-131 in patients with a negative diagnostic scan with 74 MBq I-131. Retrospective evaluation of 158 patients who received a high-dose diagnostic scan with 370 MBq I-131 because of a negative low-dose diagnostic scan with 74 MBq I-131. Special attention was paid to the patients with positive high-dose diagnostic scanning and undetectable serum Tg levels after thyroid hormone withdrawal. In 127 (80%) of patients the 370 MBq I-131 scan was negative, just like the preceding low-dose scan. In 31 (20%) of patients abnormal uptake was present on the 370 MBq diagnostic scan. In 19 of these 31 patients serum Tg was undetectable. In 15/19 the high-dose diagnostic scan proved either false positive or demonstrated clinically irrelevant minor ablation rests. In only four patients (2.5%) did the high-dose diagnostic scans reveal possibly relevant uptake caused by residual differentiated thyroid cancer. In 98% of patients a 370 MBq dose of I-131 for diagnostic whole-body scintigraphy (WBS) had no additional value. The combination of a low-dose diagnostic I-131 scan using only 74 MBq combined with a serum Tg level measurement proved sufficient for correct clinical decision making regarding whether the patient requires additional I-131 therapy. (authors)

  2. Perceived Value of Academic Support Services for Post-Secondary Students with Learning Disabilities at Accredited Institutions of the Association for Biblical Higher Education

    Science.gov (United States)

    Wilhelm, Gretchen Marie

    2014-01-01

    This study examined the perceived value of academic support service types for post-secondary students with learning disabilities in the Christian higher education milieu. Grounded in a model of service utilization (Pescosolido, 1992), the research methodology applied in this study addressed the following research question: What is the perceived…

  3. A quest for normal values of serum aminotransferase and its association with age and body mass index

    International Nuclear Information System (INIS)

    Farooq, M.A.; Farooq, Y.; Khan, M.A.

    2016-01-01

    Objective: To determine the reference range for serum alanine aminotransferase (ALT) levels for young healthy individuals in our population and to find out effects of age and body mass index on alanine aminotransferase. Study Design: Descriptive cross sectional study. Place and Duration of Study: Military Hospital Rawalpindi; from Dec 2009 to April 2010. Material and Methods: Five hundred and fifty three young healthy adults were included in the study. Detailed history was taken. Parameters like Age, height and weight were measured. Relevant investigations were carried out for each subject which included blood complete picture, Chest X-Ray, ECG, Urine routine examination, liver function tests, serum urea, serum creatinine, serum uric acid, plasma glucose (F), Anti HCV antibodies, HBsAg, HIV antibodies and VDRL. Data was analyzed using SPSS version 22. Results: Age of subjects ranged from 19 to 50 years (29 +- 6) years, BMI 15.59 to 29.8, (21.58 +- 2). Serum alanine aminotransferase ranged from 17 to 81 IU/l, (29.9 +- 8) IU/l. Serum alanine aminotransferase for subjects with body mass index more than 25 Kg/m2 was 29.6 +- 7 IU/L. There is no significant difference in value of mean ALT overall and in those with BMI of more than 25 (p=0.149) Conclusion: Mean serum alanine aminotransferase value in young healthy adults included in this study was 29.9 +- 8 IU/L which is lower than normal reference provided at present which is 40 IU/l. Statistical analysis revealed that serum ALT is not significantly influenced by age and BMI. (author)

  4. Discriminating the endogenous and exogenous urinary estrogens in human by isotopic ratio mass spectrometry and its potential clinical value.

    Science.gov (United States)

    Yang, Sheng; Zhang, Dapeng; Xu, Youxuan; Wang, Xiaobing; Liu, Xin; Wang, Shan; Wang, Jingzhu; Wu, Moutian; He, Zhenwen; Zhao, Jian; Yuan, Hong

    2013-02-01

    Estrogens were prohibited in the food producing animals by European Union (96/22/EC directive) and added to the Report on Carcinogens in United States since 2002. Due to very low concentration in serum or urine (~pg/mL), the method of control its abuse had not been fully developed. The endogenous estrogens were separated from urines of 18 adult men and women. The exogenous estrogens were chemical reference standards and over the counter preparations. Two patients of dysfunctional uterine bleeding (DUB) administered exogenous estradiol and the urines were collected for 72 h. The urinary estrogens were separated by high-performance liquid chromatography (HPLC) and confirmed. The exogenous and exogenous estrogens were analyzed by gas chromatography combustion isotope ratio mass spectrometry (GC-C-IRMS) to determine the (13)C/(12)C ratio (δ(13)C‰). The δ(13)C‰ values of reference standard of E1, E2, and E3 were -29.36±0.72, -27.98±0.35, -27.62±0.51, respectively. The δ(13)C‰ values of the endogenous E1, E2, and E3 were -21.62±1.07, -22.14±0.98, and -21.88±1.16, with Pendogenous and exogenous urinary estrogen in human. Copyright © 2012 Elsevier Inc. All rights reserved.

  5. The Effectiveness of Problem Based Learning Integrated With Islamic Values Based on ICT on Higher Order Thinking Skill and Students’ Character

    Directory of Open Access Journals (Sweden)

    Chairul Anwar

    2017-02-01

    Full Text Available The focus of this research is to known the influence of Problem Based Learning (PBL model application, that intergrated with Islamic values based on ICT, toward the ability of higher-order thinkingskill and the strenghtening of students’ characters. This research is quasy experiment type with group design pretest-postest. The research was conducted in SMA.Sampling by means of random sampling, to determine the control class and experimentalclass.Data analysis technique used is the t-test, based on the value of significance, as well as test-effect size. The research data shows that the model of problem based learning integrates Islamic values based on ICThas positive influence towards the increasing of higher-order thinking skill and the strenghtening of students’ characters compared to the students that use conventional method.The result of effect size test on experimental class in on medium category. It means that the learning which use problem based learning (PBL model, integrated with Islamic values based on ICT, can be said effective on increasing higher order thinking skillof students.

  6. Dietary calcium intake and higher body mass index in Mexican adults aged 20 to 59 years old: cross-sectional study

    Directory of Open Access Journals (Sweden)

    Mario Efraín Flores-Aldana

    2013-02-01

    Full Text Available Background. Although energy balance is the main factor that regulates body weight, recent studies suggest that calcium metabolism can modify the energy balance and help regulate body weight. Objective. To evaluate the association between the calcium intake in the diet and high body mass index in Mexican adults in the 20-59 age group. Material and methods. A cross-sectional secondary analytical study was conducted based on the 2006 Mexican National Health and Nutritional Survey (ENSANUT 2006. Food intake questionnaires applied to 16,494 adults were analyzed. After removing biologically implausible values or incomplete information, we arrived at a final sample of 15,662 adults grouped according to their body mass index. Linear regression was used to assess association between daily dietary calcium intake and body mass index. Results. There was an inverse association between dietary calcium consumption and a high body mass index. The mean calcium intake in subjects with normal body mass index was 903.9 mg/day versus 832.0 mg/day in obese subjects (p < 0.0001. Conclusion. The study corroborates existing evidence of an inverse association between the dietary calcium intake and a high body mass index.

  7. Biodegradation testing of chemicals with high Henry’s constants – separating mass and effective concentration reveals higher rate constants

    DEFF Research Database (Denmark)

    Birch, Heidi; Andersen, Henrik Rasmus; Comber, Mike

    Microextraction (HS-SPME) was applied directly on the test systems to measure substrate depletion by biodegradation relative to abiotic controls. HS-SPME was also applied to determine air to water partitioning ratios. Water phase biodegradation rate constants, kwater, were up to 72 times higher than test system...

  8. Lean body mass correction of standardized uptake value in simultaneous whole-body positron emission tomography and magnetic resonance imaging

    Science.gov (United States)

    Jochimsen, Thies H.; Schulz, Jessica; Busse, Harald; Werner, Peter; Schaudinn, Alexander; Zeisig, Vilia; Kurch, Lars; Seese, Anita; Barthel, Henryk; Sattler, Bernhard; Sabri, Osama

    2015-06-01

    This study explores the possibility of using simultaneous positron emission tomography—magnetic resonance imaging (PET-MRI) to estimate the lean body mass (LBM) in order to obtain a standardized uptake value (SUV) which is less dependent on the patients' adiposity. This approach is compared to (1) the commonly-used method based on a predictive equation for LBM, and (2) to using an LBM derived from PET-CT data. It is hypothesized that an MRI-based correction of SUV provides a robust method due to the high soft-tissue contrast of MRI. A straightforward approach to calculate an MRI-derived LBM is presented. It is based on the fat and water images computed from the two-point Dixon MRI primarily used for attenuation correction in PET-MRI. From these images, a water fraction was obtained for each voxel. Averaging over the whole body yielded the weight-normalized LBM. Performance of the new approach in terms of reducing variations of 18F-Fludeoxyglucose SUVs in brain and liver across 19 subjects was compared with results using predictive methods and PET-CT data to estimate the LBM. The MRI-based method reduced the coefficient of variation of SUVs in the brain by 41  ± 10% which is comparable to the reduction by the PET-CT method (35  ± 10%). The reduction of the predictive LBM method was 29  ± 8%. In the liver, the reduction was less clear, presumably due to other sources of variation. In conclusion, employing the Dixon data in simultaneous PET-MRI for calculation of lean body mass provides a brain SUV which is less dependent on patient adiposity. The reduced dependency is comparable to that obtained by CT and predictive equations. Therefore, it is more comparable across patients. The technique does not impose an overhead in measurement time and is straightforward to implement.

  9. Void Measurements in the Regions of Sub-Cooled and Low-Quality Boiling. Part 2. Higher Mass Velocities

    Energy Technology Data Exchange (ETDEWEB)

    Rouhani, S Z

    1966-07-15

    This report consists mostly of tables of experimental data obtained in void measurements. It is a continuation and the completing part of a previous report with the same title. The data are from the measurements in a vertical annular channel with 25 mm O.D. and 12 mm I.D. at a heated length of 1090 mm. These experiments covered pressures from 10 to 50 bars, mass velocities from 650 to 1450 kg/m -sec., heat fluxes from 60 to 120 W/cm{sup 2}, sub-coolings from 30 to 0 C, and steam qualities from 0 to 12 %. The tables include the inlet temperatures and measured wall super-heat.

  10. Implementation of a Quality Improvement Process Aimed to Deliver Higher-Value Physical Therapy for Patients With Low Back Pain: Case Report.

    Science.gov (United States)

    Karlen, Emily; McCathie, Becky

    2015-12-01

    The current state of health care demands higher-value care. Due to many barriers, clinicians routinely do not implement evidence-based care even though it is known to improve quality and reduce cost of care. The purpose of this case report is to describe a theory-based, multitactic implementation of a quality improvement process aimed to deliver higher-value physical therapy for patients with low back pain. Patients were treated from January 2010 through December 2014 in 1 of 32 outpatient physical therapy clinics within an academic health care system. Data were examined from 47,755 patients (mean age=50.3 years) entering outpatient physical therapy for management of nonspecific low back pain, with or without radicular pain. Development and implementation tactics were constructed from adult learning and change management theory to enhance adherence to best practice care among 130 physical therapists. A quality improvement team implemented 4 tactics: establish care delivery expectations, facilitate peer-led clinical and operational teams, foster a learning environment focused on meeting a population's needs, and continuously collect and analyze outcomes data. Physical therapy utilization and change in functional disability were measured to assess relative cost and quality of care. Secondarily, charge data assessed change in physical therapists' application of evidence-based care. Implementation of a quality improvement process was measured by year-over-year improved clinical outcomes, decreased utilization, and increased adherence to evidence-based physical therapy, which was associated with higher-value care. When adult learning and change management theory are combined in quality improvement efforts, common barriers to implementing evidence-based care can be overcome, creating an environment supportive of delivering higher-value physical therapy for patients with low back pain. © 2015 American Physical Therapy Association.

  11. Modelling exposure of oceanic higher trophic-level consumers to polychlorinated biphenyls: pollution 'hotspots' in relation to mass mortality events of marine mammals.

    Science.gov (United States)

    Handoh, Itsuki C; Kawai, Toru

    2014-08-30

    Marine mammals in the past mass mortality events may have been susceptible to infection because their immune systems were suppressed through the bioaccumulation of environmental pollutants such as polychlorinated biphenyls (PCBs). We compiled mortality event data sets of 33 marine mammal species, and employed a Finely-Advanced Transboundary Environmental model (FATE) to model the exposure of the global fish community to PCB congeners, in order to define critical exposure levels (CELs) of PCBs above which mass mortality events are likely to occur. Our modelling approach enabled us to describe the mass mortality events in the context of exposure of higher-trophic consumers to PCBs and to identify marine pollution 'hotspots' such as the Mediterranean Sea and north-western European coasts. We demonstrated that the CELs can be applied to quantify a chemical pollution Planetary Boundary, under which a safe operating space for marine mammals and humanity can exist. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. Association of the FTO fat mass and obesity-associated gene rs9939609 polymorphism with rewarding value of food and eating behavior in Chilean children.

    Science.gov (United States)

    Obregón Rivas, Ana Maria; Santos, Jose L; Valladares, Macarena A; Cameron, Jameson; Goldfield, Gary

    2018-03-27

    The aim of this study was to assess the association between the single-nucleotide polymorphism rs9939609 in the FTO gene and homeostatic/non-homeostatic eating behavior patterns in Chilean children. A cross-sectional study was conducted in 258 children (44% female; 8-14 y of age). Anthropometric measurements (weight, height, Z-score of height, body mass index, and waist circumference) were performed. Eating behavior was assessed using the Eating in Absence of Hunger Questionnaire; the Child Eating Behavior Questionnaire; the Three Factor Eating Questionnaire, and the Food Reinforcement Value Questionnaire. Genotype of rs9939609 was determined by a Taqman assay. Association of rs9939609 with eating behavior was assessed using non-parametric tests. Allelic frequencies of rs9939609 were estimated as 77% for the A allele and 23% for the T allele. We found that normal-weight girl A carriers had higher scores of Satiety Responsiveness and Slowness on the Eating subscale. Normal-weight boy A carriers showed significantly higher scores on the Negative Affect and lower scores of the Desire to Drink subscale. In overweight children, A carriers showed higher scores on the Food Responsiveness, Emotional Overeating, Enjoyment of Food, and Food Choice subscales and lower scores on the Satiety- Responsiveness and Slowness in Eating subscales. In obese children, we found higher scores on the Cognitive Restrained subscale and lower Food Choice. The rs9939609 A allele of the FTO gene is associated with eating behavior traits and may predispose to obesity. Copyright © 2018 Elsevier Inc. All rights reserved.

  13. A critique of massification of higher education in Poland and the United States: Mass-media discourse analysis

    Directory of Open Access Journals (Sweden)

    Łukasz Stankiewicz

    2017-01-01

    Full Text Available The nearly universal access to higher education (HE in developed countries was once praised as a great democratic achievement, and a basis for both economic development and social mobility. After the onset of the 2008 recession, the narratives changed considerably. The most radical critics of HE propose a partial “deschooling” of society by reversing the process of massification. This paper aims to present a critical discourse analysis (CAD of the “don’t go to college” discourse that became popular in Poland and the United States. I trace the differences in the way the decision to go to college is conceptualized in Poland and the U.S to the differences in dominant political ideologies – democratic and egalitarian in the U.S., paternalistic and conservative in Poland. I also show how recent changes in the actual HE systems put those ideologies at odds with the educational realities of both countries.

  14. Valores profesionales de enfermería: Una mirada hacia la formación en la Educación Superior Nursing professional values in Higher Education

    Directory of Open Access Journals (Sweden)

    Martha Díaz Flores

    2012-08-01

    Full Text Available Los valores profesionales se definen como valores humanos contextualizados y orientados a la profesión, aúnan en sus significados la relación entre los requerimientos sociales y los de la profesión, constituyen la identidad profesional por ser guía en el comportamiento en el ámbito laboral. Dentro de la Educación Superior se ha retomado la inclusión de valores en la formación, y junto a los conocimientos y habilidades, conforman la llamada formación integral. El objetivo de esta investigación fue determinar los valores profesionales en estudiantes de licenciatura en enfermería de la Universidad Autónoma del Estado de México. Material y Métodos: con un enfoque cuantitativo, se realizó un estudio transversal, exploratorio y descriptivo, a través de una encuesta basada en los valores propuestos por la American Association of Colleges of Nursing, y a partir de escalas Liker, se determinaron valores profesionales dirigidos hacia pacientes, la familia de los pacientes y el equipo médico. Resultados: se obtuvo el siguiente sistema de valores: dignidad humana, igualdad, verdad, libertad, justicia, altruismo y estética. Se observa que la mayoría de los valores se consideraron indispensables hacia el paciente, manifestando menores porcentajes hacia la familia del paciente y equipo médico sobre todo en los valores de estética, altruismo y libertad.Professional values are defined as human values contextualized and oriented to the profession, join in their meanings the relationship between social requirements and of the profession, are the professional identity as guide behavior in the workplace. The inclusion of values in the training has taken up within higher education, and along with knowledge and skills, make up the so-called comprehensive training. The objective of this research was to appreciate the professional values in students of degree in nursing from the Autonomous University of the State of Mexico. Material and methods

  15. Alteration of the magnitude of the proton magnetic moment in nuclear magnetons in connection with the changes in the atomic mass values

    Energy Technology Data Exchange (ETDEWEB)

    Mamyrin, B.A.; Aruev, N.N.; Alekseenko, S.A.

    1983-06-01

    In connection with the revision of the table values of the atomic masses and the forthcoming coordination of the values of the fundamental physical constants, the result of measurement of the proton magnetic moment in nuclear Magnetons obtained in 1971 is re-examined by taking into account recent data. With the atomic masses recognized in 1982 the proton magnetic moment expressed in nuclear magnetons without a correction for diamagnetic screening of the proton in a water molecule is found to be ..mu..sub(p)'/..mu..sub(n)=2.7927729+-0.0000012 (4.3x10/sup -5/%).

  16. Pyrolysis of Lantana camara and Mimosa pigra: Influences of temperature, other process parameters and incondensable gas evolution on char yield and higher heating value.

    Science.gov (United States)

    Mundike, Jhonnah; Collard, François-Xavier; Görgens, Johann F

    2017-11-01

    Pyrolysis of invasive non-indigenous plants, Lantana camara (LC) and Mimosa pigra (MP) was conducted at milligram-scale for optimisation of temperature, heating rate and hold time on char yield and higher heating value (HHV). The impact of scaling-up to gram-scale was also studied, with chromatography used to correlate gas composition with HHV evolution. Statistically significant effects of temperature on char yield and HHV were obtained, while heating rate and hold time effects were insignificant. Milligram-scale maximised HHVs were 30.03MJkg -1 (525°C) and 31.01MJkg -1 (580°C) for LC and MP, respectively. Higher char yields and HHVs for MP were attributed to increased lignin content. Scaling-up promoted secondary char formation thereby increasing HHVs, 30.82MJkg -1 for LC and 31.61MJkg -1 for MP. Incondensable gas analysis showed that temperature increase beyond preferred values caused dehydrogenation that decreased HHV. Similarly, CO evolution profile explained differences in optimal HHV temperatures. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. The Roche Immunoturbidimetric Albumin Method on Cobas c 501 Gives Higher Values Than the Abbott and Roche BCP Methods When Analyzing Patient Plasma Samples.

    Science.gov (United States)

    Helmersson-Karlqvist, Johanna; Flodin, Mats; Havelka, Aleksandra Mandic; Xu, Xiao Yan; Larsson, Anders

    2016-09-01

    Serum/plasma albumin is an important and widely used laboratory marker and it is important that we measure albumin correctly without bias. We had indications that the immunoturbidimetric method on Cobas c 501 and the bromocresol purple (BCP) method on Architect 16000 differed, so we decided to study these methods more closely. A total of 1,951 patient requests with albumin measured with both the Architect BCP and Cobas immunoturbidimetric methods were extracted from the laboratory system. A comparison with fresh plasma samples was also performed that included immunoturbidimetric and BCP methods on Cobas c 501 and analysis of the international protein calibrator ERM-DA470k/IFCC. The median difference between the Abbott BCP and Roche immunoturbidimetric methods was 3.3 g/l and the Roche method overestimated ERM-DA470k/IFCC by 2.2 g/l. The Roche immunoturbidimetric method gave higher values than the Roche BCP method: y = 1.111x - 0.739, R² = 0.971. The Roche immunoturbidimetric albumin method gives clearly higher values than the Abbott and Roche BCP methods when analyzing fresh patient samples. The differences between the two methods were similar at normal and low albumin levels. © 2016 Wiley Periodicals, Inc.

  18. Consumption Frequency of Foods Away from Home Linked with Higher Body Mass Index and Lower Fruit and Vegetable Intake among Adults: A Cross-Sectional Study

    Directory of Open Access Journals (Sweden)

    Rebecca A. Seguin

    2016-01-01

    Full Text Available Introduction. Consumption of foods prepared away from home (FAFH has grown steadily since the 1970s. We examined the relationship between FAFH and body mass index (BMI and fruit and vegetable (FV consumption. Methods. Frequency of FAFH, daily FV intake, height and weight, and sociodemographic data were collected using a telephone survey in 2008-2009. Participants included a representative sample of 2,001 adult men and women (mean age 54±15 years residing in King County, WA, with an analytical sample of 1,570. Frequency of FAFH was categorized as 0-1, 2–4, or 5+ times per week. BMI was calculated from self-reported height and weight. We examined the relationship between FAFH with FV consumption and BMI using multivariate models. Results. Higher frequency of FAFH was associated with higher BMI, after adjusting for age, income, education, race, smoking, marital status, and physical activity (women: p=0.001; men: p=0.003. There was a negative association between frequency of FAFH and FV consumption. FAFH frequency was significantly (p<0.001 higher among males than females (43.1% versus 54.0% eating out 0-1 meal per week, resp.. Females reported eating significantly (p<0.001 more FV than males. Conclusion. Among adults, higher frequency of FAFH was related to higher BMI and less FV consumption.

  19. Consumption Frequency of Foods Away from Home Linked with Higher Body Mass Index and Lower Fruit and Vegetable Intake among Adults: A Cross-Sectional Study

    Science.gov (United States)

    Seguin, Rebecca A.; Aggarwal, Anju; Vermeylen, Francoise; Drewnowski, Adam

    2016-01-01

    Introduction. Consumption of foods prepared away from home (FAFH) has grown steadily since the 1970s. We examined the relationship between FAFH and body mass index (BMI) and fruit and vegetable (FV) consumption. Methods. Frequency of FAFH, daily FV intake, height and weight, and sociodemographic data were collected using a telephone survey in 2008-2009. Participants included a representative sample of 2,001 adult men and women (mean age 54 ± 15 years) residing in King County, WA, with an analytical sample of 1,570. Frequency of FAFH was categorized as 0-1, 2–4, or 5+ times per week. BMI was calculated from self-reported height and weight. We examined the relationship between FAFH with FV consumption and BMI using multivariate models. Results. Higher frequency of FAFH was associated with higher BMI, after adjusting for age, income, education, race, smoking, marital status, and physical activity (women: p = 0.001; men: p = 0.003). There was a negative association between frequency of FAFH and FV consumption. FAFH frequency was significantly (p < 0.001) higher among males than females (43.1% versus 54.0% eating out 0-1 meal per week, resp.). Females reported eating significantly (p < 0.001) more FV than males. Conclusion. Among adults, higher frequency of FAFH was related to higher BMI and less FV consumption. PMID:26925111

  20. Development of a dissertation quality value-added model for humanities and social sciences programs for private higher education institutions in Thailand

    Directory of Open Access Journals (Sweden)

    Thanyasinee Laosum

    2016-09-01

    Full Text Available The purposes of this study were: (1 to evaluate the quality of dissertations in the humanities and social sciences of private higher education institutions, (2 to analyze factors affecting the quality at the student, advisor, and institute levels, and (3 to develop a quality, value-added model of the dissertations. Samples consisted of: (1 750 student dissertations in the humanities and social sciences and (2 753 questionnaire responses consisting of 633 students, 108 dissertation advisors, and 12 senior administrators in the participating institutions. A 5-point rating dissertation evaluation scale was developed for use by the researcher and her assistants. Three sets of a dissertation attribution questionnaire used by the students, advisors, and senior administrators were also developed and administered. Descriptive statistics were used with the 5-point rating data. The 3-level HLM package was used to analyze the quality, value-added model of the dissertations. The findings of the study were: (1 the overall quality of the 750 dissertations was at the standard level; (2 there were 5 factors at 3 different levels influencing the dissertation quality with 1 student factor (favorable characteristics in conducting research, 3 advisor factors (experience in research, up-to-date knowledge in research, and the advisor-student ratio, 1 institutional factor (close monitoring and management system; and (3 the quality value-added model was able to predict the variance of the dissertation quality at 36 percent.

  1. Determining Energies and Cross Sections of Individual Ions Using Higher-Order Harmonics in Fourier Transform Charge Detection Mass Spectrometry (FT-CDMS).

    Science.gov (United States)

    Harper, Conner C; Elliott, Andrew G; Lin, Haw-Wei; Williams, Evan R

    2018-06-02

    A general method for in situ measurements of the energy of individual ions trapped and weighed using charge detection mass spectrometry (CDMS) is described. Highly charged (> 300 e), individual polyethylene glycol (PEG) ions are trapped and oscillate within an electrostatic trap, producing a time domain signal. A segmented Fourier transform (FT) of this signal yields the temporal evolution of the fundamental and harmonic frequencies of ion motion throughout the 500-ms trap time. The ratio of the fundamental frequency and second harmonic (HAR) depends on the ion energy, which is an essential parameter for measuring ion mass in CDMS. This relationship is calibrated using simulated ion signals, and the calibration is compared to the HAR values measured for PEG ion signals where the ion energy was also determined using an independent method that requires that the ions be highly charged (> 300 e). The mean error of 0.6% between the two measurements indicates that the HAR method is an accurate means of ion energy determination that does not depend on ion size or charge. The HAR is determined dynamically over the entire trapping period, making it possible to observe the change in ion energy that takes place as solvent evaporates from the ion and collisions with background gas occur. This method makes it possible to measure mass changes, either from solvent evaporation or from molecular fragmentation (MS n ), as well as the cross sections of ions measured using CDMS. Graphical Abstract.

  2. Trabecular bone mineral density measured by quantitative CT of the lumbar spine in children and adolescents: reference values and peak bone mass

    International Nuclear Information System (INIS)

    Berthold, L.D.; Alzen, G.; Haras, G.; Mann, M.

    2006-01-01

    Purpose: The aim of this study was to assess bone density values in the trabecular substance of the lumbar vertebral column in children and young adults in Germany from infancy to the age of peak bone mass. Materials and Methods: We performed quantiative computed tomography (QCT) on the first lumbar vertebra in 28 children and adolescents without diseases that may influence bone metabolism (15 boys, 13 girls, mean ages 11 and 8 years, respectively). We also measured 17 healthy young adults (9 men, 8 women, mean ages 20 and 21 years). We used a Somatom Balance Scanner (Siemens, Erlangen) and the Siemens Osteo software. Scan parameters: Slice thickness 1 cm, 80 kV, 81 or 114 mAs. We measured the trabecular bone density and the area and height of the vertebra and calculated the volume and content of calcium hydroxyapatite (Ca-HA) in the trabecular substance of the first lumbar vertebra. Results: Prepubertal boys had a mean bone density of 148.5 (median [med] 150.1, standard deviation [SD] 15.4) mg/Ca-HA per ml bone, and prepubertal girls had a mean density of 149.5 (med 150.8, SD 23.5) mg/ml. We did not observe a difference between prepubertal boys and girls. After puberty there was a significant difference (p<0.001) between males and females: Mean density (male) 158.0, med 162.5, SD 24.0 mg/ml, mean density (female) 191.2, med 191.3, SD 17.7 mg/ml. The Ca-HA content in the trabecular bone of the first lumbar vertebra was 1.1 (med 1.1, SD 0.5) g for prepubertal boys and 1.1 (0.9, 0.4) g for prepubertal girls. For post-pubertal males, the mean Ca-HA content was 3.5 g, med 3.5 SD 0.5 g, and for post-pubertal females, the mean content was 2.8, med 2.7, SD 0.4 g. Conclusion: The normal trabecular bone mineral density is 150 mg/ml with a standard deviation of 20 mg/ml independent of age or gender until the beginning of puberty. Peak bone mass (bone mineral content) in the trabecular substance of the lumbar vertebral column is higher in males than in females, and peak bone

  3. Trabecular bone mineral density measured by quantitative CT of the lumbar spine in children and adolescents: reference values and peak bone mass; Trabekulaere Knochendichte der Lendenwirbelsaeule bei Kindern und Jugendlichen in der quantitativen CT: Referenzwerte und Peak Bone Mass

    Energy Technology Data Exchange (ETDEWEB)

    Berthold, L.D.; Alzen, G. [Kinderradiologie, Zentrum fuer Radiologie, Universitaetsklinikum Giessen und Marburg GmbH, Standort Giessen (Germany); Haras, G. [Siemens AG, Medical Solutions, Forchheim (Germany); Mann, M. [AG Medizinische Statistik, Universitaetsklinikum Giessen und Marburg GmbH, Standort Giessen (Germany)

    2006-12-15

    Purpose: The aim of this study was to assess bone density values in the trabecular substance of the lumbar vertebral column in children and young adults in Germany from infancy to the age of peak bone mass. Materials and Methods: We performed quantiative computed tomography (QCT) on the first lumbar vertebra in 28 children and adolescents without diseases that may influence bone metabolism (15 boys, 13 girls, mean ages 11 and 8 years, respectively). We also measured 17 healthy young adults (9 men, 8 women, mean ages 20 and 21 years). We used a Somatom Balance Scanner (Siemens, Erlangen) and the Siemens Osteo software. Scan parameters: Slice thickness 1 cm, 80 kV, 81 or 114 mAs. We measured the trabecular bone density and the area and height of the vertebra and calculated the volume and content of calcium hydroxyapatite (Ca-HA) in the trabecular substance of the first lumbar vertebra. Results: Prepubertal boys had a mean bone density of 148.5 (median [med] 150.1, standard deviation [SD] 15.4) mg/Ca-HA per ml bone, and prepubertal girls had a mean density of 149.5 (med 150.8, SD 23.5) mg/ml. We did not observe a difference between prepubertal boys and girls. After puberty there was a significant difference (p<0.001) between males and females: Mean density (male) 158.0, med 162.5, SD 24.0 mg/ml, mean density (female) 191.2, med 191.3, SD 17.7 mg/ml. The Ca-HA content in the trabecular bone of the first lumbar vertebra was 1.1 (med 1.1, SD 0.5) g for prepubertal boys and 1.1 (0.9, 0.4) g for prepubertal girls. For post-pubertal males, the mean Ca-HA content was 3.5 g, med 3.5 SD 0.5 g, and for post-pubertal females, the mean content was 2.8, med 2.7, SD 0.4 g. Conclusion: The normal trabecular bone mineral density is 150 mg/ml with a standard deviation of 20 mg/ml independent of age or gender until the beginning of puberty. Peak bone mass (bone mineral content) in the trabecular substance of the lumbar vertebral column is higher in males than in females, and peak bone

  4. Higher body mass index is associated with greater severity of alopecia in men with male-pattern androgenetic alopecia in Taiwan: a cross-sectional study.

    Science.gov (United States)

    Yang, Chao-Chun; Hsieh, Fu-Nien; Lin, Li-Yu; Hsu, Chao-Kai; Sheu, Hamm-Ming; Chen, WenChieh

    2014-02-01

    Obesity is a risk factor for multiple health problems, but its association with androgenetic alopecia (AGA) remains controversial. We sought to determine the association between body mass index (BMI) and alopecia severity in men with AGA and early-onset AGA. A cross-sectional study was conducted. The medical charts and photographs of men with a clinical diagnosis of AGA were reviewed. In all, 189 men were enrolled with a mean age of 30.8 years. In male-pattern AGA (n = 142), men with severe alopecia (grade V-VII) had higher BMI than those with mild to moderate alopecia (grade I-IV) (25.1 vs 22.8 kg/m(2), P = .01). After multivariate adjustments, the risk for severe alopecia was higher in the overweight or obese (BMI ≥24 kg/m(2)) subjects with male-pattern AGA (odds ratio 3.52, P < .01). In early-onset male-pattern AGA (n = 46), the risk for having severe alopecia was also higher in the overweight or obese subjects (odds ratio 4.97, P = .03). Parameters used to evaluate obesity were limited because of the retrospective nature of the study. Higher BMI was significantly associated with greater severity of hair loss in men with male-pattern AGA, especially in those with early-onset AGA. Copyright © 2013 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.

  5. High protein intake along with paternal part-time employment is associated with higher body fat mass among girls from South China.

    Science.gov (United States)

    Yang, Ming-Zhe; Xue, Hong-Mei; Pan, Jay; Libuda, Lars; Muckelbauer, Rebecca; Yang, Min; Quan, Liming; Cheng, Guo

    2017-05-23

    Protein intake has been suggested to be associated with body composition among western children. Our aim was to determine whether protein intake is associated with body composition among Chinese children and to investigate whether parental socioeconomic status modifies these associations. Cross-sectional data were collected from the baseline survey of an ongoing population-based prospective open cohort study conducted in 2013. In this survey, 2039 children in South China were recruited using cluster random sampling. Information of 1704 children (47% girls), aged 7-12 years from three primary schools (42 classes), on diet and anthropometry was included finally. Their daily protein intake was obtained by 3-day 24-h dietary recalls. Skinfold thickness, body height, and weight were measured to calculate percent body fat (%BF), fat mass index (FMI), and fat-free mass index (FFMI). Parental characteristics were collected by questionnaires. Among girls, protein intake was positively associated with %BF and FMI [estimate (SE) for %BF: 0.007 (0.003), p = 0.04; for FMI: 0.092 (0.002), p = 0.03], adjusted for pubertal stage, breast-feeding, maternal overweight, carbohydrate intake, energy intake, and physical activity level. Furthermore, there was interaction between paternal occupation and the relations of dietary protein with %BF and FMI (p for interaction  ≤ 0.04). None of the associations between protein intake and %BF, FMI, or FFMI was found among boys. Our data indicate that school-aged girls, but not boys, living in South China with higher dietary protein intake might have higher body fat mass, which could be modified by paternal occupation.

  6. Reference Values for the Marx Activity Rating Scale in a Young Athletic Population: History of Knee Ligament Injury Is Associated With Higher Scores.

    Science.gov (United States)

    Cameron, Kenneth L; Peck, Karen Y; Thompson, Brandon S; Svoboda, Steven J; Owens, Brett D; Marshall, Stephen W

    2015-01-01

    Activity-related patient-reported outcome measures are an important component of assessment after knee ligament injury in young and physically active patients; however, normative data for most activity scales are limited. To present reference values by sex for the Marx Activity Rating Scale (MARS) within a young and physically active population while accounting for knee ligament injury history and sex. Cross-sectional study. Level 2. All incoming freshman entering a US Service Academy in June of 2011 were recruited to participate in this study. MARS was administered to 1169 incoming freshmen (203 women) who consented to participate within the first week of matriculation. All subjects were deemed healthy and medically fit for military service on admission. Subjects also completed a baseline questionnaire that asked for basic demographic information and injury history. We calculated means with standard deviations, medians with interquartile ranges, and percentiles for ordinal and continuous variables, and frequencies and proportions for dichotomous variables. We also compared median scores by sex and history of knee ligament injury using the Kruskal-Wallis test. MARS was the primary outcome of interest. The median MARS score was significantly higher for men when compared with women (χ(2) = 13.22, df = 1, P MARS scores between men and women (χ(2) = 0.47, df = 1, P = 0.493) who reported a history of injury. Overall, median MARS scores were significantly higher among those who reported a history of knee ligament injury when compared with those who did not (χ(2) = 9.06, df = 1, P = 0.003). Assessing activity as a patient-reported outcome after knee ligament injury is important, and reference values for these instruments need to account for the influence of prior injury and sex. © 2015 The Author(s).

  7. Predictive values of Bi-Rads categories 3, 4 and 5 in non-palpable breast masses evaluated by mammography, ultrasound and magnetic resonance imaging

    International Nuclear Information System (INIS)

    Roveda Junior, Decio; Fleury, Eduardo de Castro Faria; Piato, Sebastiao; Oliveira, Vilmar Marques de; Rinaldi, Jose Francisco; Ferreira, Carlos Alberto Pecci

    2007-01-01

    Objective: To evaluate the predictive value of BI-RADS TM categories 3, 4 and 5 in non-palpable breast masses assessed by mammography, ultrasound and magnetic resonance imaging. Materials And Methods: Twenty-nine patients with BI-RADS categories 3, 4 and 5 non-palpable breast masses identified by mammograms were submitted to complementary ultrasound and magnetic resonance imaging studies, besides excisional biopsy. In total, 30 biopsies were performed. The lesions as well as their respective BI-RADS classification into 3, 4 and 5 were correlated with the histopathological results. The predictive values calculation was made by means of specific mathematical equations. Results: Negative predictive values for category 3 were: mammography, 69.23%; ultrasound, 70.58%; and magnetic resonance imaging, 100%. Positive predictive values for category 4 were: mammography, 63.63%; ultrasound, 50%; and magnetic resonance imaging, 30.76%. For category 5, positive predictive values were: mammography and ultrasound, 100%; and magnetic resonance imaging, 92.85%. Conclusion: For category 3, the negative predictive value of magnetic resonance imaging was high, and for categories 4 and 5, the positive predictive values of the three modalities were moderate. (author)

  8. The Value of Fieldwork in Life and Environmental Sciences in the Context of Higher Education: A Case Study in Learning About Biodiversity

    Science.gov (United States)

    Scott, Graham W.; Goulder, Raymond; Wheeler, Phillip; Scott, Lisa J.; Tobin, Michelle L.; Marsham, Sara

    2012-02-01

    Fieldwork is assumed by most practitioners to be an important if not essential component of a degree level education in the environmental sciences. However, there is strong evidence that as a result of a wide range of pressures (academic, financial and societal) fieldwork is in decline in the UK and elsewhere. In this paper we discuss the value of fieldwork in a higher education context and present the results of a case study which illustrates its value to student learning and the wider student experience. We used qualitative and quantitative methods to compare the impact of two learning tasks upon the affective and cognitive domains of students. We designed two tasks. One task that included fieldwork, and required students to collect organisms from the field and make labelled drawings of them, and one task that omitted the fieldwork and simply required drawing of specimens that the students had not collected. We evaluated the students' experience through structured and semi-structured questionnaires and written exercises. Students did not perceive the two tasks as being equivalent to one another. They reported that they enjoy fieldwork and value it (in the contexts of their learning at university, life-long learning, and in relation to their career aspirations) and felt that they learn more effectively in the field. Our students were better able to construct a taxonomic list of organisms that they had collected themselves, better able to recall the structural detail of these organisms and were better able to recall the detail of an ecological sampling methodology that they had personally carried out in the field rather than one that a tutor had described to them in a classroom setting. Our case study supports the growing body of evidence that fieldwork is an important way of enhancing undergraduate learning and highlights some key areas for future research.

  9. MetCCS predictor: a web server for predicting collision cross-section values of metabolites in ion mobility-mass spectrometry based metabolomics.

    Science.gov (United States)

    Zhou, Zhiwei; Xiong, Xin; Zhu, Zheng-Jiang

    2017-07-15

    In metabolomics, rigorous structural identification of metabolites presents a challenge for bioinformatics. The use of collision cross-section (CCS) values of metabolites derived from ion mobility-mass spectrometry effectively increases the confidence of metabolite identification, but this technique suffers from the limit number of available CCS values. Currently, there is no software available for rapidly generating the metabolites' CCS values. Here, we developed the first web server, namely, MetCCS Predictor, for predicting CCS values. It can predict the CCS values of metabolites using molecular descriptors within a few seconds. Common users with limited background on bioinformatics can benefit from this software and effectively improve the metabolite identification in metabolomics. The web server is freely available at: http://www.metabolomics-shanghai.org/MetCCS/ . jiangzhu@sioc.ac.cn. Supplementary data are available at Bioinformatics online. © The Author (2017). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  10. Energy spectrum based calculation of the half and the tenth value layers for brachytherapy sources using a semiempirical parametrized mass attenuation coefficient formulism

    International Nuclear Information System (INIS)

    Yue, Ning J.

    2008-01-01

    As different types of radionuclides (e.g., 131 Cs source) are introduced for clinical use in brachytherapy, the question is raised regarding whether a relatively simple method exists for the derivation of values of the half value layer (HVL) or the tenth value layer (TVL). For the radionuclide that has been clinically used for years, such as 125 I and 103 Pd, the sources have been manufactured and marketed by several vendors with different designs and structures. Because of the nature of emission of low energy photons for these radionuclides, energy spectra of the sources are very dependent on their individual designs. Though values of the HVL or the TVL in certain commonly used shielding materials are relatively small for these low energy photon emitting sources, the question remains how the variations in energy spectra affect the HVL (or TVL) values and whether these values can be calculated with a relatively simple method. A more fundamental question is whether a method can be established to derive the HVL (TVL) values for any brachytherapy sources and for different materials in a relatively straightforward fashion. This study was undertaken to answer these questions. Based on energy spectra, a well established semiempirical mass attenuation coefficient computing scheme was utilized to derive the HVL (TVL) values of different materials for different types of brachytherapy sources. The method presented in this study may be useful to estimate HVL (TVL) values of different materials for brachytherapy sources of different designs and containing different radionuclides

  11. Effects of sex, age, body mass, and capturing method on hematologic values of brown bears in Croatia.

    Science.gov (United States)

    Kusak, Josip; Rafaj, Renata Barić; Zvorc, Zdravko; Huber, Djuro; Forsek, Jadranka; Bedrica, Ljiljana; Mrljak, Vladimir

    2005-10-01

    Effects of various intrinsic and extrinsic factors on 17 hematologic values from 56 brown bears (Ursus arctos) sampled in Croatia from 1981 to 2005 were evaluated. Differences between female and male bears were detected for number of erythrocytes, sedimentation rate after 30 min, and number of leukocytes and segmented neutrophils. Significant differences between free-living vs. captive and snared vs. not snared bears were detected for the same three parameters: leukocytes, segmented neutrophils, and eosinophils. It was concluded that the physical exertion of bears snared by leg, rather than their free-living status, influenced differences of results among these groups. The obtained mean values are useful reference values for the species.

  12. Increasing the productivity of glycopeptides analysis by using higher-energy collision dissociation-accurate mass-product-dependent electron transfer dissociation.

    Science.gov (United States)

    Saba, Julian; Dutta, Sucharita; Hemenway, Eric; Viner, Rosa

    2012-01-01

    Currently, glycans are attracting attention from the scientific community as potential biomarkers or as posttranslational modifications (PTMs) of therapeutic proteins. However, structural characterization of glycoproteins and glycopeptides remains analytically challenging. Here, we report on the implementation of a novel acquisition strategy termed higher-energy collision dissociation-accurate mass-product-dependent electron transfer dissociation (HCD-PD-ETD) on a hybrid linear ion trap-orbitrap mass spectrometer. This acquisition strategy uses the complementary fragmentations of ETD and HCD for glycopeptides analysis in an intelligent fashion. Furthermore, the approach minimizes user input for optimizing instrumental parameters and enables straightforward detection of glycopeptides. ETD spectra are only acquired when glycan oxonium ions from MS/MS HCD are detected. The advantage of this approach is that it streamlines data analysis and improves dynamic range and duty cycle. Here, we present the benefits of HCD-PD-ETD relative to the traditional alternating HCD/ETD for a trainer set containing twelve-protein mixture with two glycoproteins: human serotransferrin, ovalbumin and contaminations of two other: bovine alpha 1 acid glycoprotein (bAGP) and bovine fetuin.

  13. Adolescence physical activity is associated with higher tibial pQCT bone values in adulthood after 28-years of follow-up--the Cardiovascular Risk in Young Finns Study.

    Science.gov (United States)

    Tolonen, S; Sievänen, H; Mikkilä, V; Telama, R; Oikonen, M; Laaksonen, M; Viikari, J; Kähönen, M; Raitakari, O T

    2015-06-01

    High peak bone mass and strong bone phenotype are known to be partly explained by physical activity during growth but there are few prospective studies on this topic. In this 28-year follow-up of Cardiovascular Risk in Young Finns Study cohort, we assessed whether habitual childhood and adolescence physical activity or inactivity at the age of 3-18 years were associated with adult phenotype of weight-bearing tibia and the risk of low-energy fractures. Baseline physical activity and data on clinical, nutritional and lifestyle factors were assessed separately for females and males aged 3-6-years (N=395-421) and 9-18-years (N=923-965). At the age of 31-46-years, the prevalence of low-energy fractures was assessed with a questionnaire and several tibial traits were measured with pQCT (bone mineral content (BMC; mg), total and cortical cross-sectional areas (mm(2)), trabecular (for the distal site only) and cortical (for the shaft only) bone densities (mg/cm(3)), stress-strain index (SSI; mm(3), for the shaft only), bone strength index (BSI; mg(2)/cm(4), for the distal site only) and the cortical strength index (CSI, for the shaft only)). For the statistical analysis, each bone trait was categorized as below the cohort median or the median and above and the adjusted odds ratios (OR) were determined. In females, frequent physical activity at the age of 9-18-years was associated with higher adulthood values of BSI, total and cortical areas, BMC, CSI and SSI at the tibia independently of many health and lifestyle factors (ORs 0.33-0.53, P≤0.05; P-values for trend 0.002-0.05). Cortical density at the tibial shaft showed the opposite trend (P-value for trend 0.03). Similarly in males, frequent physical activity was associated with higher values of adult total and cortical areas and CSI at the tibia (ORs 0.48-0.53, P≤0.05; P-values for trend 0.01-0.02). However, there was no evidence that childhood or adolescence physical activity was associated with lower risk of low

  14. The C242T polymorphism of the p22-phox gene (CYBA is associated with higher left ventricular mass in Brazilian hypertensive patients

    Directory of Open Access Journals (Sweden)

    Krieger José E

    2011-08-01

    Full Text Available Abstract Background Reactive oxygen species have been implicated in the physiopathogenesis of hypertensive end-organ damage. This study investigated the impact of the C242T polymorphism of the p22-phox gene (CYBA on left ventricular structure in Brazilian hypertensive subjects. Methods We cross-sectionally evaluated 561 patients from 2 independent centers [Campinas (n = 441 and Vitória (n = 120] by clinical history, physical examination, anthropometry, analysis of metabolic and echocardiography parameters as well as p22-phox C242T polymorphism genotyping. In addition, NADPH-oxidase activity was quantified in peripheral mononuclear cells from a subgroup of Campinas sample. Results Genotype frequencies in both samples were consistent with the Hardy- Weinberg equilibrium. Subjects with the T allele presented higher left ventricular mass/height2.7 than those carrying the CC genotype in Campinas (76.8 ± 1.6 vs 70.9 ± 1.4 g/m2.7; p = 0.009, and in Vitória (45.6 ± 1.9 vs 39.9 ± 1.4 g/m2.7; p = 0.023 samples. These results were confirmed by stepwise regression analyses adjusted for age, gender, blood pressure, metabolic variables and use of anti-hypertensive medications. In addition, increased NADPH-oxidase activity was detected in peripheral mononuclear cells from T allele carriers compared with CC genotype carriers (p = 0.03. Conclusions The T allele of the p22-phox C242T polymorphism is associated with higher left ventricular mass/height2.7 and increased NADPH-oxidase activity in Brazilian hypertensive patients. These data suggest that genetic variation within NADPH-oxidase components may modulate left ventricular remodeling in subjects with systemic hypertension.

  15. The value of blood oxygenation level-dependent (BOLD MR imaging in differentiation of renal solid mass and grading of renal cell carcinoma (RCC: analysis based on the largest cross-sectional area versus the entire whole tumour.

    Directory of Open Access Journals (Sweden)

    Guang-Yu Wu

    Full Text Available To study the value of assessing renal masses using different methods in parameter approaches and to determine whether BOLD MRI is helpful in differentiating RCC from benign renal masses, differentiating clear-cell RCC from renal masses other than clear-cell RCC and determining the tumour grade.Ninety-five patients with 139 renal masses (93 malignant and 46 benign who underwent abdominal BOLD MRI were enrolled. R2* values were derived from the largest cross-section (R2*largest and from the whole tumour (R2*whole. Intra-observer and inter-observer agreements were analysed based on two measurements by the same observer and the first measurement from each observer, respectively, and these agreements are reported with intra-class correlation coefficients and 95% confidence intervals. The diagnostic value of the R2* value in the evaluation was assessed with receiver-operating characteristic analysis.The intra-observer agreement was very good for R2*largest and R2*whole (all > 0.8. The inter-observer agreement of R2*whole (0.75, 95% confidence interval: 0.69~0.79 was good and was significantly improved compared with the R2*largest (0.61, 95% confidence interval: 0.52~0.68, as there was no overlap in the 95% confidence interval of the intra-class correlation coefficients. The diagnostic value in differentiating renal cell carcinoma from benign lesions with R2*whole (AUC=0.79/0.78[observer1/observer2] and R2*largest (AUC=0.75[observer1] was good and significantly higher (p=0.01 for R2*largest[observer2] vs R2*whole[observer2], p 0.7 and were not significantly different (p=0.89/0.93 for R2*largest vs R2*whole[observer1/observer2], 0.96 for R2*whole[observer1] vs R2*largest[observer2] and 0.96 for R2*whole [observer2] vs R2*largest[observer1].BOLD MRI could provide a feasible parameter for differentiating renal cell carcinoma from benign renal masses and for predicting clear-cell renal cell carcinoma grading. Compared with the largest cross

  16. Associated factors for higher lead and cadmium blood levels, and reference values derived from general population of São Paulo, Brazil

    International Nuclear Information System (INIS)

    Kira, Carmen Silvia; Sakuma, Alice Momoyo; De Capitani, Eduardo Mello; Umbelino de Freitas, Clarice; Cardoso, Maria Regina Alves; Gouveia, Nelson

    2016-01-01

    Human activities are associated with emissions of various metals into the environment, among which the heavy metals lead and cadmium stand out, as they pose a risk to human life even at low concentrations. Thus, accurate knowledge of the levels of these metals exhibited by the overall population, including children, is important. The aim of this study was to estimate the concentrations of lead and cadmium in the blood of adults, adolescents and children residing in the city of São Paulo, assess factors associated with higher lead and cadmium blood levels, and to establish reference values for this population. The study sample consisted of 669 adults over 20 years old, 264 adolescents aged 12 to 19 years old and 391 children under 11 years old from both genders. The samples were collected at the end of 2007 and during 2008 in different city zones. Higher blood lead concentration was significantly associated with gender, smoking, offal intake, area of residence and age. The blood cadmium concentration was significantly associated with gender, smoking, consumption of distilled beverages and age. The reference values of lead and cadmium established for adults above 20 years old were 33 μg/L and 0.6 μg/L, respectively, for adolescents (12 to 19 years old) were 31 μg/L and 0.6 μg/L, respectively and for children under 11 years old were 29 μg/L and 0.2 μg/L, respectively. The results of this study indicate that the exposure levels of the investigated population to lead and cadmium are low. - Highlights: • The exposure of population of São Paulo city to lead and cadmium is low. • Pb level was associated with gender, smoking, offal intake, area of residence, age. • Cd level was associated with gender, smoking, distilled beverages, age. • RV for Pb in blood for children and adolescents were 29 and 31 μg/L, respectively. • RV for Cd in blood for children and adolescents were 0.2 and 0.6 μg/L, respectively.

  17. Associated factors for higher lead and cadmium blood levels, and reference values derived from general population of São Paulo, Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Kira, Carmen Silvia, E-mail: carmkira@ial.sp.gov.br [Instituto Adolfo Lutz, Centro de Materiais de Referência, Av. Dr. Arnaldo, 355, São Paulo, SP CEP 01246-000 (Brazil); Sakuma, Alice Momoyo [Instituto Adolfo Lutz, Centro de Materiais de Referência, Av. Dr. Arnaldo, 355, São Paulo, SP CEP 01246-000 (Brazil); De Capitani, Eduardo Mello [Universidade Estadual de Campinas — UNICAMP, Faculdade de Ciências Médicas, Departamento de Clínica Médica, Centro de Controle de Intoxicações (Brazil); Umbelino de Freitas, Clarice [Secretaria de Estado da Saúde/SP, Coordenadoria de Controle de Doenças (Brazil); Cardoso, Maria Regina Alves [Universidade de São Paulo, Faculdade de Saúde Pública, Departamento de Epidemiologia (Brazil); Gouveia, Nelson [Universidade de São Paulo — USP, Faculdade de Medicina, Departamento de Medicina Preventiva (Brazil)

    2016-02-01

    Human activities are associated with emissions of various metals into the environment, among which the heavy metals lead and cadmium stand out, as they pose a risk to human life even at low concentrations. Thus, accurate knowledge of the levels of these metals exhibited by the overall population, including children, is important. The aim of this study was to estimate the concentrations of lead and cadmium in the blood of adults, adolescents and children residing in the city of São Paulo, assess factors associated with higher lead and cadmium blood levels, and to establish reference values for this population. The study sample consisted of 669 adults over 20 years old, 264 adolescents aged 12 to 19 years old and 391 children under 11 years old from both genders. The samples were collected at the end of 2007 and during 2008 in different city zones. Higher blood lead concentration was significantly associated with gender, smoking, offal intake, area of residence and age. The blood cadmium concentration was significantly associated with gender, smoking, consumption of distilled beverages and age. The reference values of lead and cadmium established for adults above 20 years old were 33 μg/L and 0.6 μg/L, respectively, for adolescents (12 to 19 years old) were 31 μg/L and 0.6 μg/L, respectively and for children under 11 years old were 29 μg/L and 0.2 μg/L, respectively. The results of this study indicate that the exposure levels of the investigated population to lead and cadmium are low. - Highlights: • The exposure of population of São Paulo city to lead and cadmium is low. • Pb level was associated with gender, smoking, offal intake, area of residence, age. • Cd level was associated with gender, smoking, distilled beverages, age. • RV for Pb in blood for children and adolescents were 29 and 31 μg/L, respectively. • RV for Cd in blood for children and adolescents were 0.2 and 0.6 μg/L, respectively.

  18. Co-creation vs. mass customization in Fashion Industry : understanding new shoppers’ differential perceived value and preferences

    OpenAIRE

    Daamen, Alexander

    2015-01-01

    Emerging literature highlights the importance of implementing user innovation in existing new product development as the offline fashion industry is stagnating. Co-creation and mass customization, denoted as an active collaboration process between fashion retailers and consumers, are user innovative concepts. There is little known how different shopper types embrace the final product outcomes of both concepts. Therefore, this research study aims to examine the differential effects on percepti...

  19. Value of body mass index in the diagnosis of obesity according to DEXA in well-controlled RA patients.

    Science.gov (United States)

    Tello-Winniczuk, Nina; Vega-Morales, David; García-Hernandez, Pedro A; Esquivel-Valerio, Jorge A; Garza-Elizondo, Mario A; Arana-Guajardo, Ana C

    Rheumatoid arthritis (RA) has an indirect effect on body composition. Body mass index (BMI) is not a valid predictor of body fat in RA patients. To evaluate the accuracy of BMI in identifying obesity diagnosed according to dual energy X-ray absorptiometry (DXA) in well-controlled RA patients. An observational, cross-sectional, descriptive, analytical study. We used 3 different cutoffs for obesity as determined by DXA: >35% total fat, >40% total fat, and >35% central fat mass (central obesity). One hundred one patients were included. We found that 35% total fat corresponded to a BMI of 24kg/m 2 , with a sensitivity of 90% and specificity of 75% (area under the curve [AUC] 0.917); 40% total fat to a BMI of 25kg/m 2 , with a sensitivity of 86% and specificity of 39% (AUC 0.822); and 35% central fat mass to a BMI of 22kg/m 2 , with a sensitivity of 97% and specificity of 84% (AUC 0.951). Obesity according to DXA was underdiagnosed when the classic BMI cutoffs were used in well-controlled RA patients. Copyright © 2016 Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología. All rights reserved.

  20. Some more evidence in the discussion of the ambiguities surrounding consumer perceived value and consumer satisfaction: A new perspective on the role of mass communication theories

    OpenAIRE

    Spais, George S.; Vasileiou, Konstantinos Z.

    2008-01-01

    The major objective of this study is to test two alternative models in order to investigate whether customer value and satisfaction represent two theoretically and empirically distinct concepts. We address the core research themes of our study using a survey. This paper contributes to marketing research by introducing a new parameter (the examination of the mass communication theories) at the growing discussion about the ambiguities surrounding marketing constructs, such as consumer perceived...

  1. Women Are Diagnosed with Type 2 Diabetes at Higher Body Mass Indices and Older Ages than Men: Korea National Health and Nutrition Examination Survey 2007-2010

    Directory of Open Access Journals (Sweden)

    Su Kyoung Kwon

    2014-02-01

    Full Text Available BackgroundMany epidemiologic studies have shown that women with type 2 diabetes have an increased risk of developing cardiovascular disease compared with men with diabetes. The aim of this study is to elucidate whether disparities of adiposity, age and insulin resistance (IR at the time of diabetes diagnosis exist between women and men in the adult Korean population.MethodsData from The Korea National Health and Nutrition Examination Survey, performed in Korea from 2007 to 2010, were used. In the survey, anthropometric data and blood samples were obtained during a fasting state. IR and β-cell function were calculated using the homeostasis model assessment (HOMA-IR and HOMA-β, respectvely.ResultsThe mean age of diabetes diagnosis was 58.5 years in women and was 55.1 years in men (P=0.015. The mean body mass index (BMI of newly diagnosed diabetes subjects was 26.1 kg/m2 in women and 25.0 kg/m2 in men (P=0.001. The BMI was inversely related to age in both genders, and the higher BMI in women than men was consistent throughout all age groups divided by decade. The HOMA-IR in women with diabetes is higher than in men with diabetes (7.25±0.77 vs. 5.20±0.32; P=0.012.ConclusionKorean adult women are diagnosed with type 2 diabetes at higher BMI and older age than men and are more insulin-resistant at the time of diabetes diagnosis. This may help explain why women with diabetes have an increased risk of developing cardiovascular disease after the diagnosis of diabetes, compared to men.

  2. A brain-derived neurotrophic factor polymorphism Val66Met identifies fibromyalgia syndrome subgroup with higher body mass index and C-reactive protein.

    Science.gov (United States)

    Xiao, Yangming; Russell, I Jon; Liu, Ya-Guang

    2012-08-01

    A common single nucleotide polymorphism (SNP) in the gene of brain-derived neurotrophic factor (BDNF) results from a substitution at position 66 from valine (Val) to methionine (Met) and may predispose to human neuropsychiatric disorders. We proposed to determine whether these BDNF gene SNPs were associated with fibromyalgia syndrome (FMS) and/or any of its typical phenotypes. Patients with FMS (N = 95) and healthy normal controls (HNC, N = 58) were studied. Serum high-sensitivity C-reactive protein (hsCRP) levels were measured using an enzyme-linked immunosorbent assay (ELISA). The BDNF SNPs were determined using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP).The BDNF SNP distribution was 65 (68%) Val/Val, 28 (30%) Val/Met, and 2 (2%) Met/Met for FMS and 40 (69%), 17(29%), and 1 (2%) for HNC, respectively. The serum high-sensitivity C-reactive protein (hsCRP)and body mass index (BMI) in FMS were higher than in HNC. The FMS with BDNF Val66Val had significantly higher mean BMI (P = 0.0001) and hsCRP (P = 0.02) than did FMS carrying the Val66Met genotype. This pattern was not found in HNC. Phenotypic measures of subjective pain, pain threshold, depression, or insomnia did not relate to either of the BDNF SNPs in FMS. The relative distribution BDNF SNPs did not differ between FMS and HNC. The BDNF Val66Met polymorphism is not selective for FMS. The BDNF Val66Val SNP identifies a subgroup of FMS with elevated hsCRP and higher BMI. This is the first study to associate a BDNF polymorphism with a FMS subgroup phenotype.

  3. The value of T/NT in FDG imaging with a coincidence camera for diagnosis of pulmonary nodules and mass lesions

    International Nuclear Information System (INIS)

    Sun Da; Zhan Hongwei; Xu Wei; Ye Xiaojuan; Liu Qichang

    2004-01-01

    Objectives: To assess the value of T/NT in FDG imaging with a coincidence camera for diagnosis of pulmonary nodules and mass lesions. Methods: 18F-FDG imaging were performed in 57 patients with a mean age of 62.18 (range from 33 83 years old) for diagnosis of pulmonary nodules and mass lesions using a gamma camera with 1 inch crystal in coincidence mode (Siemens E.comduet). 175 296 MBq (5 8 mci) of 18F-FDG was given by iv on an empty stomach at least for 6 hours, and a whole body imaging without brain and legs was performed after 40 60 minutes. The count rate of target ROI and no-target ROI (T/NT) were calculated as a semiquantative analysis to differentiate malignant from inflammatory lesions. The result was compared with CT, MRI, and/or pathology. Results: The mean value of T/NT in malignant lesions (N=45) in lungs is 4.32 (range 1.61 10.62). But it is 1.52 (range 1.37 1.95) in inflammatory lesions (N=17) in lungs, and 4.09 (range 2.2 7.01) in lung tuberculosis lesions (N=5). In 45 malignant, the value of T/NT is less than 2.0 in only 3 lesions. So the overlapping of T/NT value is very little between malignant and inflammatory lesions. But there is full overlapping of T/NT value between malignant and tuberculosis lesions. Conclusions: Focal pulmonary nodules and mass lesions are commonly encountered in clinical practice, and PET with 18F-FDG has proved to be an accurate noninvasive test for identifying pulmonary malignant lesions. The technique of semiquantity with T/NT is useful to differentiate malignant from inflammatory lesions. But it is invalidate for distinguishing malignant from tuberculosis lesions. (authors)

  4. Higher Adolescent Body Mass Index is Associated with Lower Regional Gray and White Matter Volumes and Lower Levels of Positive Emotionality

    Directory of Open Access Journals (Sweden)

    James T Kennedy

    2016-09-01

    Full Text Available Adolescent obesity is associated with an increased chance of developing serious health risks later in life. Identifying the neurobiological and personality factors related to increases in adiposity is important to understanding what drives maladaptive consummatory and exercise behaviors that result in obesity. Previous research has largely focused on adults with few findings published on interactions among adiposity, brain structure, and personality. In this study, Voxel Based Morphometry (VBM was used to identify associations between gray and white matter volumes and increasing adiposity, as measured by Body Mass Index percentile (BMI%, in 137 adolescents (age range: 9-20 years, Body Mass Index percentile range: 5.16-99.56. Variations in gray and white matter volume and BMI% were then linked to individual differences in personality measures from the Multidimensional Personality Questionnaire (MPQ. After controlling for age and other covariates, BMI% correlated negatively with gray matter volume in the bilateral caudate (right: partial r = -0.338, left: r -0.404, medial prefrontal cortex (partial r = -0.339, anterior cingulate (partial r = -0.312, bilateral frontal pole (right: partial r = -0.368, left: r= -0.316, and uncus (partial r = -0.475 as well as white matter volume bilaterally in the anterior limb of the internal capsule (right: partial r = -0.34, left: r = -0.386, extending to the left middle frontal subgyral white matter. Agentic Positive Emotionality (PEM-AG was correlated negatively with BMI% (partial r = -0.384. PEM-AG was correlated positively with gray matter volume in the right uncus (partial r = 0.329. These results suggest that higher levels of adiposity in adolescents are associated with lower trait levels in reward-related personality domains, as well as structural variations in brain regions associated with reward processing, control, and sensory integration.

  5. Discrepancy of sodium mass fraction determined by INAA in the NIST SRM1547 and SRM1515 reference materials and their certified values

    International Nuclear Information System (INIS)

    Kamenik, Jan; Kucera, Jan

    2015-01-01

    Determination of sodium content in NIST standard reference materials (SRM) SRM 1547 and SRM 1515 in recent years yielded values higher than NIST certified values. Similarly, increased values were published for SRM 1547 by several laboratories, however, published sodium values SRM 1515 are in general in agreement with the certified value. Additional analysis of SRM 1547 and SRM 1515 using NIST SRM 3152a Sodium Standard Solution as a calibrator confirmed increased Na values. Inhomogeneity indicating external contamination of the stock material was not found. Moreover, increased Na value was also determined for freshly opened bottle of SRM 1547 material. Analysis of the historical material A-2 from our archive, which is identical with SRM 1515 and was distributed by NIST prior to the SRM 1515 certification and stored in a polyethylene vial, yielded a value in agreement with the certified value. A hypothesis was formulated that sodium in SRM 1547 and SRM 1515 materials could have been increasing after certification, perhaps due to the release of sodium from the glass bottle. (author)

  6. A preclinical simulated dataset of S-values and investigation of the impact of rescaled organ masses using the MOBY phantom

    International Nuclear Information System (INIS)

    Kostou, Theodora; Papadimitroulas, Panagiotis; Kagadis, George C; Loudos, George

    2016-01-01

    Nuclear medicine and radiation therapy, although well established, are still rapidly evolving, by exploiting animal models, aiming to define precise dosimetry in molecular imaging protocols. The purpose of the present study was to create a dataset based on the MOBY phantom for the calculation of organ-to-organ S-values of commonly used radionuclides. S-values of most crucial organs were calculated using specific biodistributions with a whole-body heterogeneous source. In order to determine the impact of the varying organs’ size on the S-values, and based on the fact that the anatomic properties of the organs are correlated with S-values, dosimetric calculations were performed by simulating the MOBY-version 2 model with different whole-body masses. The GATE Monte Carlo simulation toolkit was used for all simulations. Two mouse models of different body masses were developed to calculate the S-values of eight commonly used radioisotopes in nuclear imaging studies, namely 18 F, 68 Ga, 131 I, 111 In, 177 Lu, and 99m Tc, 90 Y and 188 Re. The impact of modified mass of the source organs in S-values was investigated with 18 F, and 90 Y in five different scalings of the source organs. Based on realistic preclinical exams, three mouse models, 22, 28 and 34 g, were used as input in the GATE simulator based on realistic preclinical exams to calculate the S-values of the six radioisotopes used. Whole body activity distributions were used as the source organ. The simulation procedure was validated in terms of extracting individual organ-to-organ S-values, and consequently in calculating the new S-values using a heterogeneous activity distribution as a source. The calculation was validated with 18 F source in a 30 g mouse model. For the generation of the new S-values with heterogeneous activity sources, four organs were used for the calculation of a single S-value. The absorbed doses per organ were compared with previously published reports. The validation procedure of 18 F

  7. Higher body mass index and lower intake of dairy products predict poor glycaemic control among Type 2 Diabetes patients in Malaysia.

    Science.gov (United States)

    Shu, Ping Soon; Chan, Yoke Mun; Huang, Soo Lee

    2017-01-01

    This cross-sectional study was designed to determine factors contributing to glyceamic control in order to provide better understanding of diabetes management among Type 2 Diabetes patients. A pre-tested structured questionnaire was used to obtain information on socio-demographic and medical history. As a proxy measure for glycaemic control, glycosylated haemoglobin (HbA1c) was obtained as secondary data from the medical reports. Perceived self-care barrier on diabetes management, diet knowledge and skills, and diet quality were assessed using pretested instruments. With a response rate of 80.3%, 155 subjects were recruited for the study. Mean HbA1c level of the subjects was 9.02 ± 2.25% with more than 70% not able to achieve acceptable level in accordance to WHO recommendation. Diet quality of the subjects was unsatisfactory especially for vegetables, fruits, fish and legumes as well as from the milk and dairy products group. Higher body mass index (BMI), poorer medication compliance, lower diet knowledge and skill scores and lower intake of milk and dairy products contributed significantly on poor glycaemic control. In conclusion, while perceived self-care barriers and diet quality failed to predict HbA1c, good knowledge and skill ability, together with appropriate BMI and adequate intake of dairy products should be emphasized to optimize glycaemic control among type 2 diabetes patients.

  8. Higher body mass index and lower intake of dairy products predict poor glycaemic control among Type 2 Diabetes patients in Malaysia.

    Directory of Open Access Journals (Sweden)

    Ping Soon Shu

    Full Text Available This cross-sectional study was designed to determine factors contributing to glyceamic control in order to provide better understanding of diabetes management among Type 2 Diabetes patients. A pre-tested structured questionnaire was used to obtain information on socio-demographic and medical history. As a proxy measure for glycaemic control, glycosylated haemoglobin (HbA1c was obtained as secondary data from the medical reports. Perceived self-care barrier on diabetes management, diet knowledge and skills, and diet quality were assessed using pretested instruments. With a response rate of 80.3%, 155 subjects were recruited for the study. Mean HbA1c level of the subjects was 9.02 ± 2.25% with more than 70% not able to achieve acceptable level in accordance to WHO recommendation. Diet quality of the subjects was unsatisfactory especially for vegetables, fruits, fish and legumes as well as from the milk and dairy products group. Higher body mass index (BMI, poorer medication compliance, lower diet knowledge and skill scores and lower intake of milk and dairy products contributed significantly on poor glycaemic control. In conclusion, while perceived self-care barriers and diet quality failed to predict HbA1c, good knowledge and skill ability, together with appropriate BMI and adequate intake of dairy products should be emphasized to optimize glycaemic control among type 2 diabetes patients.

  9. Higher pre-pregnancy body mass index is associated with excessive gestational weight gain in normal weight Chinese mothers with gestational diabetes.

    Science.gov (United States)

    Yang, Yue; Wei, Qiong; Yu, Hong; Wang, Pin; Xia, Wenqing; Huang, Rong; Cai, Rongrong; Sun, Haixia; Wang, Shaohua

    2016-05-01

    To assess how pre-pregnancy body mass index (BMI) affects pregnancy outcome and total gestational weight gain (GWG) in a cohort of women with gestational diabetes (GDM). Pregnant women at 24-28 gestational weeks diagnosed with GDM were classified as normal weight (pre-pregnancy BMI, 18.5-24.9 kg/m(2) ) or overweight (pre-pregnancy BMI, 25.0-29.9 kg/m(2) ). GWG was derived from the self-reported pre-pregnancy and pre-delivery weights, and analyzed using 2009 Institute of Medicine categories. A total of 106 GDM women were categorized as normal weight (n = 79) or overweight (n = 27). No statistically significant differences were found between the groups in terms of various obstetrical and neonatal outcomes. Higher pre-pregnancy BMI, however, was associated with excessive GWG during pregnancy (difference between groups, P = 0.013). Furthermore, pre-pregnancy BMI (OR, 0.529; 95%CI: 0.377-0.742; P = 0.000) and pre-pregnancy overweight (OR, 3.825; 95%CI: 1.469-9.959; P = 0.006) were independent factors of GWG. Among Chinese GDM women, overweight GDM mothers gain excessive weight during pregnancy. Regulation of pre-pregnancy bodyweight might be an appropriate precaution against excessive GWG. © 2016 Japan Society of Obstetrics and Gynecology.

  10. Insulin-like growth factor II (IGF II) in human brain: regional distribution of IGF II and of higher molecular mass forms

    International Nuclear Information System (INIS)

    Haselbacher, G.K.; Schwab, M.E.; Pasi, A.; Humbel, R.E.

    1985-01-01

    Twenty-four distinct areas of human brain were analyzed for the presence of insulin-like growth factor (IGF). As reported for cerebrospinal fluid, only IGF II-like immunoreactivity, but no significant amounts of IGF I-like immunoreactivity, could be found. Upon gel permeation chromatography, two to five distinct size classes were separated on the basis of their immunoreactivity. Radioimmunoassays and a bioassay also gave results indistinguishable from those of serum IGF II. The highest amounts of IGF II-like immunoreactivity occur in the anterior pituitary. This is up to 100 times more than in most other brain regions analyzed. The higher molecular mass immunoreactive species were partially characterized. After immunoaffinity purification, the 38- and 26-kDa species are active in a bioassay. Specific IGF-binding protein activity could be shown after purification of the 38- and 26-kDa species on an IGF-affinity column. The 13-kDa species released significant amounts of 7.5-kDa material. The results are interpreted as evidence for the presence of IGF II synthesized locally in human brain

  11. The prognostic value of body-mass index on mortality in older adults with dementia living in nursing homes.

    Science.gov (United States)

    de Souto Barreto, Philipe; Cadroy, Yves; Kelaiditi, Eirini; Vellas, Bruno; Rolland, Yves

    2017-04-01

    A protective effect of obesity on death has been reported in the context of various co-morbidities. We studied if the obesity paradox applied to nursing home (NH) older residents according to dementia status. Prospective data from 3741 NH residents from France. All-cause mortality was the dependent measure. Subjects were categorized according with body mass index (BMI) as underweight, normal-weight, overweight, and obese. Dementia status was obtained from medical charts. Cox regressions were performed. There were 344 (9.2%) residents who were underweight, 1367 (43.8%) normal weight, 1069 (28.6%) overweight and 691 (18.5%) obese. 1083 (28.9%) people died during follow-up. In residents with dementia, mortality risk was reduced by almost half in overweight and obese people (HRs of 0.60 [0.48-0.76] and 0.53 [0.38-0.75], respectively; p paradox in very old and functionally limited NH residents. Therefore, weight loss in NH residents, particularly in people with dementia, should be considered with extreme caution even for obese people. Copyright © 2015 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

  12. A Comparison of Vertical Stiffness Values Calculated from Different Measures of Center of Mass Displacement in Single-Leg Hopping.

    Science.gov (United States)

    Mudie, Kurt L; Gupta, Amitabh; Green, Simon; Hobara, Hiroaki; Clothier, Peter J

    2017-02-01

    This study assessed the agreement between K vert calculated from 4 different methods of estimating vertical displacement of the center of mass (COM) during single-leg hopping. Healthy participants (N = 38) completed a 10-s single-leg hopping effort on a force plate, with 3D motion of the lower limb, pelvis, and trunk captured. Derived variables were calculated for a total of 753 hop cycles using 4 methods, including: double integration of the vertical ground reaction force, law of falling bodies, a marker cluster on the sacrum, and a segmental analysis method. Bland-Altman plots demonstrated that K vert calculated using segmental analysis and double integration methods have a relatively small bias (0.93 kN⋅m -1 ) and 95% limits of agreement (-1.89 to 3.75 kN⋅m -1 ). In contrast, a greater bias was revealed between sacral marker cluster and segmental analysis (-2.32 kN⋅m -1 ), sacral marker cluster and double integration (-3.25 kN⋅m -1 ), and the law of falling bodies compared with all methods (17.26-20.52 kN⋅m -1 ). These findings suggest the segmental analysis and double integration methods can be used interchangeably for the calculation of K vert during single-leg hopping. The authors propose the segmental analysis method to be considered the gold standard for the calculation of K vert during single-leg, on-the-spot hopping.

  13. Higher order radiative corrections to electron anomaly in QED; a remark on asymptotic behaviour of vacuum polarization insertions and explicit analytic values of the first six ladder graphs

    International Nuclear Information System (INIS)

    Caffo, M.; Turrini, S.; Remiddi, E.

    1978-04-01

    As a comment to a recent paper by B. Lautrup we show that the series of multiple lowest order vacuum polarization insertions in the lowest vertex graph is convergent for finite Pauli-Villars regularizing mass, and becomes divergent in the limit of infinite regularizing mass. We then evaluate, analytically, the contributions due to the first twelve vacuum polarization insertions. We consider also the contributions to the electron anomaly due to the vertex ladder graphs. They are all positive and growing fast; the ratio between two successive ones is also growing, up to 2.95 for the last two we evaluate. (orig.) [de

  14. Multi-tissue analysis of co-expression networks by higher-order generalized singular value decomposition identifies functionally coherent transcriptional modules.

    Science.gov (United States)

    Xiao, Xiaolin; Moreno-Moral, Aida; Rotival, Maxime; Bottolo, Leonardo; Petretto, Enrico

    2014-01-01

    Recent high-throughput efforts such as ENCODE have generated a large body of genome-scale transcriptional data in multiple conditions (e.g., cell-types and disease states). Leveraging these data is especially important for network-based approaches to human disease, for instance to identify coherent transcriptional modules (subnetworks) that can inform functional disease mechanisms and pathological pathways. Yet, genome-scale network analysis across conditions is significantly hampered by the paucity of robust and computationally-efficient methods. Building on the Higher-Order Generalized Singular Value Decomposition, we introduce a new algorithmic approach for efficient, parameter-free and reproducible identification of network-modules simultaneously across multiple conditions. Our method can accommodate weighted (and unweighted) networks of any size and can similarly use co-expression or raw gene expression input data, without hinging upon the definition and stability of the correlation used to assess gene co-expression. In simulation studies, we demonstrated distinctive advantages of our method over existing methods, which was able to recover accurately both common and condition-specific network-modules without entailing ad-hoc input parameters as required by other approaches. We applied our method to genome-scale and multi-tissue transcriptomic datasets from rats (microarray-based) and humans (mRNA-sequencing-based) and identified several common and tissue-specific subnetworks with functional significance, which were not detected by other methods. In humans we recapitulated the crosstalk between cell-cycle progression and cell-extracellular matrix interactions processes in ventricular zones during neocortex expansion and further, we uncovered pathways related to development of later cognitive functions in the cortical plate of the developing brain which were previously unappreciated. Analyses of seven rat tissues identified a multi-tissue subnetwork of co

  15. Multi-tissue analysis of co-expression networks by higher-order generalized singular value decomposition identifies functionally coherent transcriptional modules.

    Directory of Open Access Journals (Sweden)

    Xiaolin Xiao

    2014-01-01

    Full Text Available Recent high-throughput efforts such as ENCODE have generated a large body of genome-scale transcriptional data in multiple conditions (e.g., cell-types and disease states. Leveraging these data is especially important for network-based approaches to human disease, for instance to identify coherent transcriptional modules (subnetworks that can inform functional disease mechanisms and pathological pathways. Yet, genome-scale network analysis across conditions is significantly hampered by the paucity of robust and computationally-efficient methods. Building on the Higher-Order Generalized Singular Value Decomposition, we introduce a new algorithmic approach for efficient, parameter-free and reproducible identification of network-modules simultaneously across multiple conditions. Our method can accommodate weighted (and unweighted networks of any size and can similarly use co-expression or raw gene expression input data, without hinging upon the definition and stability of the correlation used to assess gene co-expression. In simulation studies, we demonstrated distinctive advantages of our method over existing methods, which was able to recover accurately both common and condition-specific network-modules without entailing ad-hoc input parameters as required by other approaches. We applied our method to genome-scale and multi-tissue transcriptomic datasets from rats (microarray-based and humans (mRNA-sequencing-based and identified several common and tissue-specific subnetworks with functional significance, which were not detected by other methods. In humans we recapitulated the crosstalk between cell-cycle progression and cell-extracellular matrix interactions processes in ventricular zones during neocortex expansion and further, we uncovered pathways related to development of later cognitive functions in the cortical plate of the developing brain which were previously unappreciated. Analyses of seven rat tissues identified a multi

  16. What Do Chinese and Foreign Universities Value about Their Strategic Alliances? Exploring a Dimension of Higher Education Alliances in a Cross Cultural Context

    Science.gov (United States)

    Willis, Mike

    2003-01-01

    There are now over 5,000 alliances between Chinese and foreign universities but there is little research on how managers from the two sides value the various aspects of their educational alliances. This research finds that both sides valued a range of alliance levels, types, activities, sizes and structures but there were significant differences.…

  17. Mass-shell properties of the dynamical quark mass

    International Nuclear Information System (INIS)

    Reinders, L.J.; Stam, K.

    1986-07-01

    We discuss the running dynamical quark mass in the framework of the operator product expansion. It is shown that for vertical strokep 2 vertical stroke>m 2 the quark-condensate part of the quark self energy has no contributions of order m 2 or higher, and is frozen to its mass-shell value for smaller vertical strokep 2 vertical stroke. (orig.)

  18. Parental body mass index and blood pressure are associated with higher body mass index and blood pressure in their adult offspring: a cross-sectional study in a resource-limited setting in northern Peru.

    Science.gov (United States)

    Carrillo-Larco, Rodrigo M; Bernabé-Ortiz, Antonio; Sal Y Rosas, Víctor G; Sacksteder, Katherine A; Diez-Canseco, Francisco; Cárdenas, María K; Gilman, Robert H; Miranda, J Jaime

    2018-05-01

    High body mass index (BMI) and blood pressure (BP) are major contributors to the high burden of non-communicable diseases in adulthood. Individual high-risk and population approaches for prevention require newer strategies to target these risk factors and focusing on the family to introduce prevention initiatives appears as a promising scenario. Characterisation of the relationship between BMI and BP among the adult members of a given family merits evaluation. We conducted a secondary analysis of an implementation study in Tumbes, Peru, benefiting from data derived from families with at least one adult offspring. The exposures of interest were the BMI, systolic BP (SBP) and diastolic BP (DBP) of the mother and father. The outcomes were the BMI, SBP and DBP of the offspring. Mixed-effects linear regression models were conducted. The mean age of the offspring, mothers and fathers was 29 (SD: 9.5), 54 (SD: 11.8) and 59 (SD: 11.6) years, respectively. Father's BMI was associated with a quarter-point increase in offspring BMI, regardless of the sex of the offspring. Mother's BMI had a similar effect on the BMI of her sons, but had no significant effect on her daughters'. Mother's SBP was associated with almost one-tenth of mmHg increase in the SBP of the adult offspring. There was no evidence of an association for DBP. In families with adult members, the higher the parents' BMI and SBP, the higher their adult offspring's levels will be. © 2018 The Authors. Tropical Medicine & International Health Published by John Wiley & Sons Ltd.

  19. A Futile Search for Values and Pedagogy? A Discursive Analysis of the Marketing Messages of Branch-Campuses in Higher Education Hubs

    Science.gov (United States)

    Karram, Grace

    2014-01-01

    Higher education has become a key strategy for the economic development of certain city-states that are positioning themselves as higher education hubs, recruiting both students and foreign providers. This article presents the findings of a research study that examined the online messages of foreign branch-campuses in education hubs (Dubai, Hong…

  20. Enhanced transfer of organic matter to higher trophic levels caused by ocean acidification and its implications for export production: A mass balance approach.

    Science.gov (United States)

    Boxhammer, Tim; Taucher, Jan; Bach, Lennart T; Achterberg, Eric P; Algueró-Muñiz, María; Bellworthy, Jessica; Czerny, Jan; Esposito, Mario; Haunost, Mathias; Hellemann, Dana; Ludwig, Andrea; Yong, Jaw C; Zark, Maren; Riebesell, Ulf; Anderson, Leif G

    2018-01-01

    Ongoing acidification of the ocean through uptake of anthropogenic CO2 is known to affect marine biota and ecosystems with largely unknown consequences for marine food webs. Changes in food web structure have the potential to alter trophic transfer, partitioning, and biogeochemical cycling of elements in the ocean. Here we investigated the impact of realistic end-of-the-century CO2 concentrations on the development and partitioning of the carbon, nitrogen, phosphorus, and silica pools in a coastal pelagic ecosystem (Gullmar Fjord, Sweden). We covered the entire winter-to-summer plankton succession (100 days) in two sets of five pelagic mesocosms, with one set being CO2 enriched (~760 μatm pCO2) and the other one left at ambient CO2 concentrations. Elemental mass balances were calculated and we highlight important challenges and uncertainties we have faced in the closed mesocosm system. Our key observations under high CO2 were: (1) A significantly amplified transfer of carbon, nitrogen, and phosphorus from primary producers to higher trophic levels, during times of regenerated primary production. (2) A prolonged retention of all three elements in the pelagic food web that significantly reduced nitrogen and phosphorus sedimentation by about 11 and 9%, respectively. (3) A positive trend in carbon fixation (relative to nitrogen) that appeared in the particulate matter pool as well as the downward particle flux. This excess carbon counteracted a potential reduction in carbon sedimentation that could have been expected from patterns of nitrogen and phosphorus fluxes. Our findings highlight the potential for ocean acidification to alter partitioning and cycling of carbon and nutrients in the surface ocean but also show that impacts are temporarily variable and likely depending upon the structure of the plankton food web.

  1. Approach to characterization of the higher order structure of disulfide-containing proteins using hydrogen/deuterium exchange and top-down mass spectrometry.

    Science.gov (United States)

    Wang, Guanbo; Kaltashov, Igor A

    2014-08-05

    Top-down hydrogen/deuterium exchange (HDX) with mass spectrometric (MS) detection has recently matured to become a potent biophysical tool capable of providing valuable information on higher order structure and conformational dynamics of proteins at an unprecedented level of structural detail. However, the scope of the proteins amenable to the analysis by top-down HDX MS still remains limited, with the protein size and the presence of disulfide bonds being the two most important limiting factors. While the limitations imposed by the physical size of the proteins gradually become more relaxed as the sensitivity, resolution and dynamic range of modern MS instrumentation continue to improve at an ever accelerating pace, the presence of the disulfide linkages remains a much less forgiving limitation even for the proteins of relatively modest size. To circumvent this problem, we introduce an online chemical reduction step following completion and quenching of the HDX reactions and prior to the top-down MS measurements of deuterium occupancy of individual backbone amides. Application of the new methodology to the top-down HDX MS characterization of a small (99 residue long) disulfide-containing protein β2-microglobulin allowed the backbone amide protection to be probed with nearly a single-residue resolution across the entire sequence. The high-resolution backbone protection pattern deduced from the top-down HDX MS measurements carried out under native conditions is in excellent agreement with the crystal structure of the protein and high-resolution NMR data, suggesting that introduction of the chemical reduction step to the top-down routine does not trigger hydrogen scrambling either during the electrospray ionization process or in the gas phase prior to the protein ion dissociation.

  2. Enhanced transfer of organic matter to higher trophic levels caused by ocean acidification and its implications for export production: A mass balance approach.

    Directory of Open Access Journals (Sweden)

    Tim Boxhammer

    Full Text Available Ongoing acidification of the ocean through uptake of anthropogenic CO2 is known to affect marine biota and ecosystems with largely unknown consequences for marine food webs. Changes in food web structure have the potential to alter trophic transfer, partitioning, and biogeochemical cycling of elements in the ocean. Here we investigated the impact of realistic end-of-the-century CO2 concentrations on the development and partitioning of the carbon, nitrogen, phosphorus, and silica pools in a coastal pelagic ecosystem (Gullmar Fjord, Sweden. We covered the entire winter-to-summer plankton succession (100 days in two sets of five pelagic mesocosms, with one set being CO2 enriched (~760 μatm pCO2 and the other one left at ambient CO2 concentrations. Elemental mass balances were calculated and we highlight important challenges and uncertainties we have faced in the closed mesocosm system. Our key observations under high CO2 were: (1 A significantly amplified transfer of carbon, nitrogen, and phosphorus from primary producers to higher trophic levels, during times of regenerated primary production. (2 A prolonged retention of all three elements in the pelagic food web that significantly reduced nitrogen and phosphorus sedimentation by about 11 and 9%, respectively. (3 A positive trend in carbon fixation (relative to nitrogen that appeared in the particulate matter pool as well as the downward particle flux. This excess carbon counteracted a potential reduction in carbon sedimentation that could have been expected from patterns of nitrogen and phosphorus fluxes. Our findings highlight the potential for ocean acidification to alter partitioning and cycling of carbon and nutrients in the surface ocean but also show that impacts are temporarily variable and likely depending upon the structure of the plankton food web.

  3. Normal values of regional left ventricular myocardial thickness, mass and distribution-assessed by 320-detector computed tomography angiography in the Copenhagen General Population Study

    DEFF Research Database (Denmark)

    Hindsø, Louise; Fuchs, Andreas; Kühl, Jørgen Tobias

    2017-01-01

    regional normal reference values of the left ventricle. The aim of this study was to derive reference values of regional LV myocardial thickness (LVMT) and mass (LVMM) from a healthy study group of the general population using cardiac computed tomography angiography (CCTA). We wanted to introduce LV...... myocardial distribution (LVMD) as a measure of regional variation of the LVMT. Moreover, we wanted to determine whether these parameters varied between men and women. We studied 568 (181 men; 32%) adults, free of cardiovascular disease and risk factors, who underwent 320-detector CCTA. Mean age was 55 (range...... 40-84) years. Regional LVMT and LVMM were measured, according to the American Heart Association's 17 segment model, using semi-automatic software. Mean LVMT were 6.6 mm for men and 5.4 mm for women (p normal LV was thickest in the basal septum (segment 3; men = 8.3 mm; women = 7.2 mm...

  4. Lay people's interpretation of ethical values related to mass vaccination; the case of A(H1N1) vaccination campaign in the province of Quebec (French Canada).

    Science.gov (United States)

    Massé, Raymond; Désy, Michel

    2014-12-01

    Pandemic influenza ethics frameworks are based on respect of values and principles such as regard for autonomy, responsibility, transparency, solidarity and social justice. However, very few studies have addressed the way in which the general population views these moral norms. (i) To analyse the receptiveness of the population of French-speaking Quebecers to certain ethical principles promoted by public health authorities during the AH1N1 vaccination campaign. (ii) To add to the limited number of empirical studies that examine the population's perception of ethical values. Eight months after the end of the AH1N1 vaccination campaign in the Province of Quebec (Canada), 100 French-speaking Quebecers were assembled in ten focus groups. Discussions focussed on the level of respect shown by public health authorities for individual autonomy, the limits of appeals for solidarity, the balance between vaccination efficiency and social justice towards non-prioritized subpopulations, vaccination as a demonstration of civic duty and social responsibility. The population acknowledged a high level of individual responsibility towards family members and agreed to vaccination to protect children and ageing parents. However, the concepts of civic duty and solidarity did not elucidate unanimous support, despite the fact that social justice stood out as a dominant value of public morals. The ethical principles promoted in influenza pandemic ethics frameworks are subject to reinterpretation by the population. An ethic of public health must consider their understanding of the fundamental values that legitimize mass vaccination. © 2012 John Wiley & Sons Ltd.

  5. [Simultaneous determination of delta13C values of glycerol and ethanol in wine by liquid chromatography coupled with isotope ratio mass spectrometry].

    Science.gov (United States)

    Li, Xuemin; Jia, Guangqun; Cao, Yanzhong; Zhang, Jinjie; Wang, Lei; Sun, Huiyuan

    2013-12-01

    A novel procedure was established for the characterization of delta13C values of glycerol and ethanol in wine by liquid chromatography-isotope ratio mass spectrometry (LC-IRMS). Several parameters influencing the separation of glycerol and ethanol from wine matrix were optimized. The precision and accuracy of the proposed method were 0.15 per thousand to 0.26 per thousand and 0.11 per thousand to 0.28 per thousand, respectively. The results obtained for 40 wine samples displayed that the delta13C value of glycerol ranged from--26.87 per thousand to--32.96 per thousand and that of ethanol ranged from--24.06 per thousand to--28.29 per thousand. Close correlations (R = 0.82) were obtained between the delta13C values of glycerol and ethanol. The proposed method didn't need complex sample treatment, and the delta13C values of glycerol and ethanol in wine can be simultaneously determined, thus improving the method in terms of simplicity and speed compared with traditional methods.

  6. Fat-Free Mass and Fasting Glucose Values in Patients with and without Statin Therapy Assigned to Age Groups between 75 Years

    Directory of Open Access Journals (Sweden)

    Alexander Dzien

    2013-02-01

    Full Text Available Objective: The aging-associated changes in body composition result in an increased cardiometabolic risk. A tremendous reduction of cardiovascular morbidity and mortality can be obtained by statin therapy. Statins are well tolerated, with myopathy as the most serious negative side effect. Some recently published studies indicate that the incidence of type 2 diabetes might be increased during intensified statin therapy. The aim of our study was to investigate whether statin therapy has an influence on the aging-associated changes in fat-free mass (FFM. Methods: A total of 3,280 persons attending a medical outdoor center between January 2005 and July 2011 were assigned to 3 age groups from 75 years. Clinical data, body mass index (BMI, and body composition were evaluated in the different age groups in patients with and without statin therapy. To analyze the impact of statin use on FFM, we regressed a patient's FFM on an interaction term between statin use and age and other control variables. Results: Aging was associated with a decrease in BMI and FFM, while fat mass continuously increased up to the age of >75 years. This was paralleled by a continuous increase in fasting glucose levels in patients with and without statin therapy. The loss of FFM between the age group 75 years was more pronounced in statin-treated patients (10.88% than in non-statin users (8.47%. Creatine phosphokinase values revealed a decrease of 7.77 U/l between the age groups 75 years in non-statin users and of 14.75 U/l in statin users. Statistical analysis indicated that the effect of statin therapy on FFM is more pronounced in younger than in older patients. Conclusions: Patients under statin therapy seem to be more vulnerable to the aging-associated lowering of FFM. Diagnostic procedures and interventions to prevent a loss of muscle mass might be of particular advantage in elderly patients under statin therapy.

  7. The Predictive Value of Job Demands and Resources on the Meaning of Work and Organisational Commitment across Different Age Groups in the Higher Education Sector

    Science.gov (United States)

    Anthun, Kirsti Sarheim; Innstrand, Siw Tone

    2016-01-01

    This study examines the predictive value of job demands and resources on the meaning of work and organisational commitment across three age groups; young workers (age group of workers (30-49 years) and older workers (>50 years). Data were collected from a survey conducted among university employees (N = 3,066).…

  8. An Examination of the Value of Overall Trust and Commitment Associated with Service Complexity in Higher Education Information Technology Outsourcing Relationships

    Science.gov (United States)

    Falk, Monica I.

    2012-01-01

    Enterprise information systems (EIS) governance provides guidance, structure, and rules for companies within industry who use information technology (IT) support services, and in particular, for outsourced IT support. This study focuses on outsourcing from the client perspective for higher education and uses the qualitative methodology with a…

  9. The Pisa pre-main sequence tracks and isochrones. A database covering a wide range of Z, Y, mass, and age values

    Science.gov (United States)

    Tognelli, E.; Prada Moroni, P. G.; Degl'Innocenti, S.

    2011-09-01

    Context. In recent years new observations of pre-main sequence stars (pre-MS) with Z ≤ Z⊙ have been made available. To take full advantage of the continuously growing amount of data of pre-MS stars in different environments, we need to develop updated pre-MS models for a wide range of metallicity to assign reliable ages and masses to the observed stars. Aims: We present updated evolutionary pre-MS models and isochrones for a fine grid of mass, age, metallicity, and helium values. Methods: We use a standard and well-tested stellar evolutionary code (i.e. FRANEC), that adopts outer boundary conditions from detailed and realistic atmosphere models. In this code, we incorporate additional improvements to the physical inputs related to the equation of state and the low temperature radiative opacities essential to computing low-mass stellar models. Results: We make available via internet a large database of pre-MS tracks and isochrones for a wide range of chemical compositions (Z = 0.0002-0.03), masses (M = 0.2-7.0 M⊙), and ages (1-100 Myr) for a solar-calibrated mixing length parameter α (i.e. 1.68). For each chemical composition, additional models were computed with two different mixing length values, namely α = 1.2 and 1.9. Moreover, for Z ≥ 0.008, we also provided models with two different initial deuterium abundances. The characteristics of the models have been discussed in detail and compared with other work in the literature. The main uncertainties affecting theoretical predictions have been critically discussed. Comparisons with selected data indicate that there is close agreement between theory and observation. Tracks and isochrones are available on the web at the http://astro.df.unipi.it/stellar-models/Tracks and isochrones are also available in electronic form at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/533/A109

  10. The Higher-Ed Organizational-Scholar Tension: How Scholarship Compatibility and the Alignment of Organizational and Faculty Skills, Values and Support Affects Scholar's Performance and Well-Being.

    Science.gov (United States)

    Pereyra-Rojas, Milagros; Mu, Enrique; Gaskin, James; Lingham, Tony

    2017-01-01

    Scholars and institutions alike are concerned with academic productivity. Scholars not only further knowledge in their professional fields, they also bring visibility and prestige to themselves and their institutions, which in turn attracts research grants and more qualified faculty and graduate students. Many studies have been done on scholar productivity, and many of them focus on individual factors such as gender, marital status, and individual psychological characteristics. Also, a few studies are concerned about scholars' well-being. We propose a causal model that considers the compatibility of the scholarship dimensions valued by scholars and institutions and their academic alignment with actual institutional recognition and support. We test our causal model with data from a survey of 803 faculty participants. Our findings shed light on how the above academic factors affect not just academic productivity but also a scholar's well-being. Importantly, we show that academic alignment plays a crucial mediating role when predicting productivity and well-being. These results have important implications for university administrators who develop, and faculty who work under, policies designed to foster professional development and scholarship.

  11. Early Metabolome Profiling and Prognostic Value in Paraquat-Poisoned Patients: Based on Ultraperformance Liquid Chromatography Coupled To Quadrupole Time-of-Flight Mass Spectrometry.

    Science.gov (United States)

    Hu, Lufeng; Hong, Guangliang; Tang, Yahui; Wang, Xianqin; Wen, Congcong; Lin, Feiyan; Lu, Zhongqiu

    2017-12-18

    Paraquat (PQ) has caused countless deaths throughout the world. There remains no effective treatment for PQ poisoning. Here we study the blood metabolome of PQ-poisoned patients using ultraperformance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry (UPLC/Q-TOF MS). Patients were divided into groups according to blood PQ concentration. Healthy subjects served as controls. Metabolic features were statistically analyzed using multivariate pattern-recognition techniques to identify the most important metabolites. Selected metabolites were further compared with a series of clinical indexes to assess the prognostic value. PQ-poisoned patients showed substantial differences compared with healthy subjects. Based on variable of importance in the project (VIP) values and statistical analysis, 17 metabolites were selected and identified. These metabolites well-classified low PQ-poisoned patients, high PQ-poisoned patients, and healthy subjects, which was better than that of a complete blood count (CBC). Among the 17 metabolites, 20:3/18:1-PC (PC), LPA (0:0/16:0) (LPA), 19-oxo-deoxycorticosterone (19-oxo-DOC), and eicosapentaenoic acid (EPA) had prognostic value. In particular, EPA was the most sensitive one. Besides, the levels of EPA was correlated with LPA and 19-oxo-DOC. If EPA was excessively consumed, then prognosis was poor. In conclusion, the serum metabolome is substantially perturbed by PQ poisoning. EPA is the most important biomarker in early PQ poisoning.

  12. Differentiating benign from malignant solid breast masses: value of shear wave elastography according to lesion stiffness combined with greyscale ultrasound according to BI-RADS classification.

    Science.gov (United States)

    Evans, A; Whelehan, P; Thomson, K; Brauer, K; Jordan, L; Purdie, C; McLean, D; Baker, L; Vinnicombe, S; Thompson, A

    2012-07-10

    The aim of this study was to assess the performance of shear wave elastography combined with BI-RADS classification of greyscale ultrasound images for benign/malignant differentiation in a large group of patients. One hundred and seventy-five consecutive patients with solid breast masses on routine ultrasonography undergoing percutaneous biopsy had the greyscale findings classified according to the American College of Radiology BI-RADS. The mean elasticity values from four shear wave images were obtained. For mean elasticity vs greyscale BI-RADS, the performance results against histology were sensitivity: 95% vs 95%, specificity: 77% vs 69%, Positive Predictive Value (PPV): 88% vs 84%, Negative Predictive Value (NPV): 90% vs 91%, and accuracy: 89% vs 86% (all P>0.05). The results for the combination (positive result from either modality counted as malignant) were sensitivity 100%, specificity 61%, PPV 82%, NPV 100%, and accuracy 86%. The combination of BI-RADS greyscale and shear wave elastography yielded superior sensitivity to BI-RADS alone (P=0.03) or shear wave alone (P=0.03). The NPV was superior in combination compared with either alone (BI-RADS P=0.01 and shear wave P=0.02). Together, BI-RADS assessment of greyscale ultrasound images and shear wave ultrasound elastography are extremely sensitive for detection of malignancy.

  13. The influence of different referencing methods on the accuracy of δ(13) C value measurement of ethanol fuel by gas chromatography/combustion/isotope ratio mass spectrometry.

    Science.gov (United States)

    Neves, Laura A; Rodrigues, Janaína M; Daroda, Romeu J; Silva, Paulo R M; Ferreira, Alexandre A; Aranda, Donato A G; Eberlin, Marcos N; Fasciotti, Maíra

    2015-11-15

    Brazil is the largest producer of sugar cane bioethanol in the world. Isotope ratio mass spectrometry (IRMS) is the technique of choice to certify the origin/raw materials for ethanol production, but the lack of certified reference materials (CRMs) for accurate measurements of δ(13) C values traceable to Vienna Pee Dee Belemnite (VPDB), the international zero point for (13) C/(12) C measurements, certified and compatible with gas chromatography (GC)/IRMS instruments may compromise the accuracy of δ(13) C determinations. We evaluated the influence of methods for the calibration and normalization of raw δ(13) C values of ethanol samples. Samples were analyzed by GC/C/IRMS using two different GC columns. Different substances were used as isotopic standards for the working gas calibration. The δ(13) C values obtained with the three methods of normalization were statistically compared with those obtained with elemental analyzer (EA)/IRMS, since the δ(13) C results obtained using EA are traceable to VPDB via the NBS 22 reference material. It was observed that both the isotopic reference material for CO2 calibration and the GC column have a major effect on the δ(13) C measurements, leading to a bias of almost 2-3 ‰ in the δ(13) C values. All three methods of normalization were equivalent in performance, enabling an improvement in the GC/C/IRMS accuracy, compared with the EA/IRMS reference values for the samples. All the methods of CO2 calibration, chromatography and normalization presented in this work demonstrated several sources of traceability and accuracy loss for the determination of δ(13) C values in ethanol fuel samples by GC/C/IRMS. This work has also shown the importance of using proper CRMs traceable to VPBD that should be compatible and certified using GC/C/IRMS, ideally in a wide range of δ(13) C values. This is important not only for bioethanol fuel samples, but also for many analytes commonly analyzed by IRMS. Copyright © 2015 John Wiley & Sons

  14. Mass of the 158Sm

    International Nuclear Information System (INIS)

    Zhao Kui; Guo Jiyu; Lu Xiuqin; Cheng Yehao; Huang Xiaolin; Ma Yong; Li Shuyuan; Ruan Ming; Li Zhichang; Jiang Chenglie

    1997-01-01

    A preliminary result was reported for the experiment to determine the mass of the heavier neutron-rich nucleus 158 Sm using the 160 Gd( 18 O, 20 Ne) two proton transfer reaction in last progress report. The average Q-value of (4.046 +- 0.102) MeV for the 160 Gd( 18 O, 20 Ne) 158 Sm reaction is given. A mass excess for 158 Sm of (-65.738 +- 0.102) MeV was derived. This is the first experimentally measured value of the mass of 158 Sm which is about 450 keV higher than the evaluation value from systematic trends listed in the 1993 atomic mass table. The new prediction shows better agreement with the measured values and a significant improvement over the earlier FRDM (finite-range droplet model) value

  15. Forming technology motivational-valued attitudes toward healthy appearance and lifestyle for students institutes of higher Ministry of internal affairs of Russia

    Directory of Open Access Journals (Sweden)

    Klimenko B.A.

    2010-10-01

    Full Text Available Directions of forming healthy lifestyle are considered for students. 62 students took part in experiment. New conception of the health physical training is grounded high-quality for students. Tests are developed as evaluated by the measure of formed of healthy lifestyle for students. Offered approach to the maintainance of professional health, level of physical preparedness at the change of appearance and lifestyle. It is set that the author program forms for students motivational-valued attitude toward the healthy lifestyle.

  16. Measurement of the delta34S value in methionine by double spike multi-collector thermal ionization mass spectrometry using Carius tube digestion.

    Science.gov (United States)

    Mann, Jacqueline L; Kelly, W Robert

    2010-09-15

    Methionine is an essential amino acid and is the primary source of sulfur for humans. Using the double spike ((33)S-(36)S) multi-collector thermal ionization mass spectrometry (MC-TIMS) technique, three sample bottles of a methionine material obtained from the Institute for Reference Materials and Measurements have been measured for delta(34)S and sulfur concentration. The mean delta(34)S value, relative to Vienna Canyon Diablo Troilite (VCDT), determined was 10.34 +/- 0.11 per thousand (n = 9) with the uncertainty reported as expanded uncertainties (U). These delta(34)S measurements include a correction for blank which has been previously ignored in studies of sulfur isotopic composition. The sulfur concentrations for the three bottles range from 56 to 88 microg/g. The isotope composition and concentration results demonstrate the high accuracy and precision of the DS-MC-TIMS technique for measuring sulfur in methionine.

  17. The additional value of bioelectrical impedance analysis-derived muscle mass as a screening tool in geriatric assessment for fall prevention.

    Science.gov (United States)

    Van Puyenbroeck, Karolien; Roelandts, Lieven; Van Deun, Thomas; Van Royen, Paul; Verhoeven, Veronique

    2012-01-01

    The decline in skeletal muscle in old age is a factor in the development of functional limitations. The objective of this study was to assess if there is a correlation between muscle mass based on bioelectrical impedance analysis (BIA) detection and the fall incidence in nursing home residents and to examine the risk factors for falling in nursing home residents. This prospective cohort study was part of a longitudinal study on nutritional issues in 52 nursing homes in Antwerp (Belgium) from October 2007 to April 2008. Two hundred and seventy-six people aged 65 years and older were included. Each subject was assessed with BIA, the timed get-up-and-go test, the Katz score, the Mini Nutritional Assessment - Short Form and the 36-Item Short Form Health Survey. The primary outcome parameter was fall incidence during the study. The prevalence of sarcopenia varied from 24.3 to 81.5% depending on which definition was used. No association was found between BIA-derived muscle mass and fall incidence. Logistic regression analysis showed that gait speed (odds ratio 1.029; p = 0.003) and mental health (odds ratio 0.981; p = 0.015) are significantly associated with fall incidence in nursing homes. A receiver operating characteristic curve showed that none of the BIA-derived muscle parameters are good predictors of the risk of falling. This study shows that there is no association between sarcopenia based on BIA and fall incidence and that BIA-derived muscle mass has no additional value in predicting fall incidents compared to the timed get-up-and-go test. Copyright © 2012 S. Karger AG, Basel.

  18. RuP{sub 2}-based catalysts with platinum-like activity and higher durability for the hydrogen evolution reaction at all pH values

    Energy Technology Data Exchange (ETDEWEB)

    Pu, Zonghua; Amiinu, Ibrahim Saana; Kou, Zongkui; Li, Wenqiang; Mu, Shichun [State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology (China)

    2017-09-11

    Highly active, stable, and cheap Pt-free catalysts for the hydrogen evolution reaction (HER) are under increasing demand for future energy conversion systems. However, developing HER electrocatalysts with Pt-like activity that can function at all pH values still remains as a great challenge. Herein, based on our theoretical predictions, we design and synthesize a novel N,P dual-doped carbon-encapsulated ruthenium diphosphide (RuP{sub 2} rate at NPC) nanoparticle electrocatalyst for HER. Electrochemical tests reveal that, compared with the Pt/C catalyst, RuP{sub 2} rate at NPC not only has Pt-like HER activity with small overpotentials at 10 mA cm{sup -2} (38 mV in 0.5 m H{sub 2}SO{sub 4}, 57 mV in 1.0 m PBS and 52 mV in 1.0 m KOH), but demonstrates superior stability at all pH values, as well as 100 % Faradaic yields. Therefore, this work adds to the growing family of transition-metal phosphides/heteroatom-doped carbon heterostructures with advanced performance in HER. (copyright 2017 Wiley-VCH Verlag GmbH and Co. KGaA, Weinheim)

  19. Mass discrimination

    Energy Technology Data Exchange (ETDEWEB)

    Broeckman, A. [Rijksuniversiteit Utrecht (Netherlands)

    1978-12-15

    In thermal ionization mass spectrometry the phenomenon of mass discrimination has led to the use of a correction factor for isotope ratio-measurements. The correction factor is defined as the measured ratio divided by the true or accepted value of this ratio. In fact this factor corrects for systematic errors of the whole procedure; however mass discrimination is often associated just with the mass spectrometer.

  20. Higher Education: How Freshmen and First-Year Journalism and Mass Communication Students at HBCUs and PWUs Used the Internet in Their Decision

    Science.gov (United States)

    Crawford, Jerry, II

    2013-01-01

    This study set out to explore how the Internet was used by Journalism and Mass Communications Program students at Historically Black Colleges and Universities and Predominately White Universities in their college choice and if these institutions were able to provide the information the respondents were looking for in their search. The study found…

  1. In folio study of carbonic anhydrase and Rubisco activities in higher C{sub 3} plants using {sup 18}O and mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Peltier, G.; Despax, V.; Dimon, B.; Rumeau, D.; Tourneux, C.

    1994-12-31

    This document studies the effects of a mild water stress and carbonic anhydrase activity by ethoxyzolamide (EZA) on the diffusion of CO{sub 2} in leaves, by {sup 18}O labelling of O{sub 2} and of CO{sub 2} associated to mass spectrometry. (A.B.). 5 refs., 2 figs.

  2. Solvability of a (p, n-p-type multi-point boundary-value problem for higher-order differential equations

    Directory of Open Access Journals (Sweden)

    Yuji Liu

    2003-12-01

    Full Text Available In this article, we study the differential equation $$ (-1^{n-p} x^{(n}(t=f(t,x(t,x'(t,dots,x^{(n-1}(t, $$ subject to the multi-point boundary conditions $$displaylines{ x^{(i}(0=0 quad hbox{for }i=0,1,dots,p-1,cr x^{(i}(1=0 quad hbox{for }i=p+1,dots,n-1,cr sum_{i=1}^malpha_ix^{(p}(xi_i=0, }$$ where $1le ple n-1$. We establish sufficient conditions for the existence of at least one solution at resonance and another at non-resonance. The emphasis in this paper is that $f$ depends on all higher-order derivatives. Examples are given to illustrate the main results of this article.

  3. Mass of the spirals galaxies

    Energy Technology Data Exchange (ETDEWEB)

    Maupome, L; Pismis, P; Aguilar, L [Universidad Nacional Autonoma de Mexico, Mexico City. Inst. de Astronomia

    1981-01-01

    In an earlier paper we have found that the total mass of galaxies-especially of the spirals-based on values published until 1975, decreased as the Hubble type varied from Sa through Sc and Irregulars. It was also pointed out that masses determined from the hydrogen 21-cm line were higher than the optically determined masses. To investigate the cause of these tendencies we have estimated the masses using an analytic rotation curve of Brandt adjusted to the optical observations in order to include all the mass of a galaxy up to the last observed point. Although the masses computed in this manner were found to be larger, as expected, the decrease of mass with Hubble type found earlier is confirmed. However, there is a discrepancy in the earlier types (Sa, Sab) in that their radio-masses are smaller than the optically determined ones. At present, the cause of this is not clear.

  4. Determination of Histidine pKa Values in the Propeptides of Furin and Proprotein Convertase 1/3 Using Histidine Hydrogen-Deuterium Exchange Mass Spectrometry.

    Science.gov (United States)

    Elferich, Johannes; Williamson, Danielle M; David, Larry L; Shinde, Ujwal

    2015-08-04

    Propeptides of proprotein convertases regulate activation of their protease domains by sensing the organellar pH within the secretory pathway. Earlier experimental work highlighted the importance of a conserved histidine residue within the propeptide of a widely studied member, furin. A subsequent evolutionary analysis found an increase in histidine content within propeptides of secreted eukaryotic proteases compared with their prokaryotic orthologs. However, furin activates in the trans-golgi network at a pH of 6.5 while a paralog, proprotein convertase 1/3, activates in secretory vesicles at a pH of 5.5. It is unclear how a conserved histidine can mediate activation at two different pH values. In this manuscript, we measured the pKa values of histidines within the propeptides of furin and proprotein convertase 1/3 using a histidine hydrogen-deuterium exchange mass spectrometry approach. The high density of histidine residues combined with an abundance of basic residues provided challenges for generation of peptide ions with unique histidine residues, which were overcome by employing ETD fragmentation. During this analysis, we found slow hydrogen-deuterium exchange in residues other than histidine at basic pH. Finally, we demonstrate that the pKa of the conserved histidine in proprotein convertase 1/3 is acid-shifted compared with furin and is consistent with its lower pH of activation.

  5. The value of energy spectral CT in the differential diagnosis between benign and malignant soft tissue masses of the musculoskeletal system.

    Science.gov (United States)

    Sun, Xin; Shao, Xiaodong; Chen, Haisong

    2015-06-01

    To explore the value of energy spectral CT in the differential diagnosis between benign and malignant tumor of the musculoskeletal system. Energy spectral CT scan was performed on 100 patients with soft tissue mass caused by musculoskeletal tumors found by MRI. Solid areas with homogenous density were chosen as region of interests (ROI), avoiding necrosis, hemorrhage and calcification region. Select the optimal keV on single energy images, and then the keV-CT curve was automatically generated. All 100 cases of tumors proved by histological examination were divided into four groups, 38 cases were in benign group, 10 cases in borderline group, 49 cases in malignant group, and 3 cases of lipoma (that were analyzed separately since its curve was arc shaped, significantly different from other curves). The formula used to calculate the slope of spectral curve was as follows: slope=(Hu40 keV-Hu80 keV)/40. As the slope was steep within the range of 40-80 keV based on preliminary observations, 40 keV and 80 keV were used as the reference points to calculate the slope value of the energy spectral curve. Kruskal-Wallis rank sum test was applied for statistical analysis, and Pbenign and malignant group, benign and borderline group were of statistical significance (Pbenign and malignant tumor of the musculoskeletal system. Arc shaped curve is a specific sign for tumors containing abundant fat. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  6. Características Agronômicas, Massa de Forragem e Valor Nutritivo de Brachiaria decumbens em Sistema Silvipastoril Agronomics Characteristics, Forage Mass and Nutritional Value of Brachiaria decumbens in a Silvopastoral System

    Directory of Open Access Journals (Sweden)

    Carlos Renato Tavares Castro

    2010-02-01

    Full Text Available

    Avaliaram-se os efeitos de três porcentagens de sombreamento (0, 29% e 45%, proporcionado pelas leguminosas arbóreas Acacia angustissima, A. mangium, A. auriculiformis, Albizia lebbek e Gliricidia sepium, sobre características agronômicas, e o valor nutritivo do pasto de Brachiaria decumbens, durante o inverno, a primavera e o verão. Foi adotado o delineamento experimental de blocos casualizados, com três repetições. O sombreamento influenciou positivamente a massa de forragem, na primavera e no verão. No inverno, a maior massa de forragem foi obtida sob sol pleno. Os teores de proteína bruta aumentaram com o sombreamento, na primavera, mas não se modificaram em função das porcentagens de sombra, no inverno e no verão. Pelo produto da massa de forragem e o teor de proteína bruta, obtiveram-se as quantidades de proteína bruta por área, que foram maiores sob sombreamento mais intenso, na primavera e no verão. Os teores de fibra em detergente neutro e a digestibilidade in vitro da matéria seca não apresentaram tendência consistente com as porcentagens de sombreamento, em função da forte interação deste tratamento com a estação do ano.

     

    doi: 10.4336/2009.pfb.60.19

    The agronomic traits and nutritive value of Brachiaria decumbens pasture were evaluated under three shade percentages (0.29% and 45%, provided by leguminous trees (Acacia angustissima, A. mangium, A. auriculiformis, Albizia lebbek e Gliricidia sepium, during winter, spring and summer seasons. The experimental design was randomized blocks, with three replications. The forage mass was positively influenced by shading, in spring and summer seasons. In winter, the higher forage mass was observed in full sunlight condition. The values of crude protein increased in spring with shading, but did not vary with shade percentage in winter and summer seasons. The crude protein quantity per area, obtained by product between forage mass and crude protein

  7. Fear, Sadness and Hope: Which Emotions Maximize Impact of Anti-Tobacco Mass Media Advertisements among Lower and Higher SES Groups?

    Science.gov (United States)

    Durkin, Sarah; Bayly, Megan; Brennan, Emily; Biener, Lois; Wakefield, Melanie

    2018-01-01

    Emotive anti-tobacco advertisements can increase quitting. Discrete emotion theories suggest evoking fear may be more effective than sadness; less research has focused on hope. A weekly cross-sectional survey of smokers and recent quitters (N = 7683) measured past-month quit attempts. The main predictor was level of exposure to four different types of anti-tobacco advertisements broadcast in the two months prior to quit attempts: advertisements predominantly evoking fear, sadness, hope, or evoking multiple negative emotions (i.e., fear, guilt, and/or sadness). Greater exposure to fear-evoking advertisements (OR = 2.16, p < .01) increased odds of making a quit attempt and showed similar effectiveness among those in lower and higher SES areas. Greater exposure to advertisements evoking multiple negative emotions increased quit attempts (OR = 1.70, p < .01), but interactions indicated this was driven by those in lower SES, but not higher SES areas. Greater exposure to hope-evoking advertisements enhanced effects of fear-evoking advertisements among those in higher SES, but not lower SES areas. Findings suggest to be maximally effective across the whole population avoid messages evoking sadness and use messages eliciting fear. If the aim is to specifically motivate those living in lower SES areas where smoking rates are higher, multiple negative emotion messages, but not hope-evoking messages, may also be effective.

  8. Making sense of policy choices: understanding the roles of value predispositions, mass media, and cognitive processing in public attitudes toward nanotechnology

    Science.gov (United States)

    Ho, Shirley S.; Scheufele, Dietram A.; Corley, Elizabeth A.

    2010-10-01

    Using a nationally representative telephone survey of 1,015 adults in the United States, this study examines how value predispositions, communication variables, and perceptions of risks and benefits are associated with public support for federal funding of nanotechnology. Our findings show that highly religious individuals were less supportive of funding of nanotech than less religious individuals, whereas individuals who held a high deference for scientific authority were more supportive of funding of the emerging technology than those low in deference. Mass media use and elaborative processing of scientific news were positively associated with public support for funding, whereas factual scientific knowledge had no significant association with policy choices. The findings suggest that thinking about and reflecting upon scientific news promote better understanding of the scientific world and may provide a more sophisticated cognitive structure for the public to form opinions about nanotech than factual scientific knowledge. Finally, heuristic cues including trust in scientists and perceived risks and benefits of nanotech were found to be associated with public support for nanotech funding. We conclude with policy implications that will be useful for policymakers and science communication practitioners.

  9. Value of three-dimensional volume rendering images in the assessment of the centrality index for preoperative planning in patients with renal masses.

    Science.gov (United States)

    Sofia, C; Magno, C; Silipigni, S; Cantisani, V; Mucciardi, G; Sottile, F; Inferrera, A; Mazziotti, S; Ascenti, G

    2017-01-01

    To evaluate the precision of the centrality index (CI) measurement on three-dimensional (3D) volume rendering technique (VRT) images in patients with renal masses, compared to its standard measurement on axial images. Sixty-five patients with renal lesions underwent contrast-enhanced multidetector (MD) computed tomography (CT) for preoperative imaging. Two readers calculated the CI on two-dimensional axial images and on VRT images, measuring it in the plane that the tumour and centre of the kidney were lying in. Correlation and agreement of interobserver measurements and inter-method results were calculated using intraclass correlation (ICC) coefficients and the Bland-Altman method. Time saving was also calculated. The correlation coefficients were r=0.99 (ppresent study showed that VRT and axial images produce almost identical values of CI, with the advantages of greater ease of execution and a time saving of almost 50% for 3D VRT images. In addition, VRT provides an integrated perspective that can better assist surgeons in clinical decision making and in operative planning, suggesting this technique as a possible standard method for CI measurement. Copyright © 2016 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

  10. Differential quantitative proteomics of Porphyromonas gingivalis by linear ion trap mass spectrometry: Non-label methods comparison, q-values and LOWESS curve fitting

    Science.gov (United States)

    Xia, Qiangwei; Wang, Tiansong; Park, Yoonsuk; Lamont, Richard J.; Hackett, Murray

    2007-01-01

    Differential analysis of whole cell proteomes by mass spectrometry has largely been applied using various forms of stable isotope labeling. While metabolic stable isotope labeling has been the method of choice, it is often not possible to apply such an approach. Four different label free ways of calculating expression ratios in a classic "two-state" experiment are compared: signal intensity at the peptide level, signal intensity at the protein level, spectral counting at the peptide level, and spectral counting at the protein level. The quantitative data were mined from a dataset of 1245 qualitatively identified proteins, about 56% of the protein encoding open reading frames from Porphyromonas gingivalis, a Gram-negative intracellular pathogen being studied under extracellular and intracellular conditions. Two different control populations were compared against P. gingivalis internalized within a model human target cell line. The q-value statistic, a measure of false discovery rate previously applied to transcription microarrays, was applied to proteomics data. For spectral counting, the most logically consistent estimate of random error came from applying the locally weighted scatter plot smoothing procedure (LOWESS) to the most extreme ratios generated from a control technical replicate, thus setting upper and lower bounds for the region of experimentally observed random error.

  11. Nickel quantification in serum by a validated sector-field inductively coupled plasma mass spectrometry method: Assessment of tentative reference values for an Italian population.

    Science.gov (United States)

    Bocca, Beatrice; Forte, Giovanni; Ronchi, Anna; Gaggeri, Raffaella; Alimonti, Alessandro; Minoia, Claudio

    2006-01-01

    The daily exposure to Ni from food, industrial processes, jewellery and coins makes the determination of Ni in human serum an important way to monitor the health status in non-occupationally exposed subjects. To this end, a method based on sector-field inductively coupled plasma mass spectrometry was developed and validated. The limits of detection (LoD) and quantification (LoQ), sensitivity, linearity range, trueness, repeatability, within-laboratory reproducibility and robustness were the considered issues of the validation process. The uncertainty associated with the measurements was also calculated, according to the Eurachem/Citac Guide. The method LoD and LoQ were 0.03 and 0.09 ng mL(-1), linearity was over two order of magnitude, trueness was -3.57%, and the repeatability and reproducibility showed relative standard deviations equal to 4.56% and 6.52%, respectively. The relative expanded uncertainty was 21.8% at the Ni levels found in the general population. The tentative reference value for serum Ni was 0.466 +/- 0.160 ng mL(-1) with a related interval between 0.226 and 1.026 ng mL(-1). Copyright 2006 John Wiley & Sons, Ltd.

  12. Making sense of policy choices: understanding the roles of value predispositions, mass media, and cognitive processing in public attitudes toward nanotechnology

    International Nuclear Information System (INIS)

    Ho, Shirley S.; Scheufele, Dietram A.; Corley, Elizabeth A.

    2010-01-01

    Using a nationally representative telephone survey of 1,015 adults in the United States, this study examines how value predispositions, communication variables, and perceptions of risks and benefits are associated with public support for federal funding of nanotechnology. Our findings show that highly religious individuals were less supportive of funding of nanotech than less religious individuals, whereas individuals who held a high deference for scientific authority were more supportive of funding of the emerging technology than those low in deference. Mass media use and elaborative processing of scientific news were positively associated with public support for funding, whereas factual scientific knowledge had no significant association with policy choices. The findings suggest that thinking about and reflecting upon scientific news promote better understanding of the scientific world and may provide a more sophisticated cognitive structure for the public to form opinions about nanotech than factual scientific knowledge. Finally, heuristic cues including trust in scientists and perceived risks and benefits of nanotech were found to be associated with public support for nanotech funding. We conclude with policy implications that will be useful for policymakers and science communication practitioners.

  13. Performance, emission and combustion characteristics of a branched higher mass, C3 alcohol (isopropanol blends fuelled medium duty MPFI SI engine

    Directory of Open Access Journals (Sweden)

    Harish Sivasubramanian

    2017-04-01

    Full Text Available With growing concerns about environmental pollution caused by automobiles, biofuels containing oxygen – also known as oxygenates – are being researched very rigorously. In this article, we have inspected the use of isopropanol/gasoline blends, as fuel in a 4 – cylinder Spark Ignition engine with Multi-Point Fuel Injection System. Isopropanol was mixed with Unleaded Gasoline in proportions of 10, 20 and 30% by volume (IPA10, IPA20 and IPA30. It is found that with the use of isopropanol/gasoline blends in Spark Ignition Engine, Brake Thermal Efficiency and NOx emissions increased whereas carbon monoxide and hydrocarbon emissions decreased. When the spark timing was retarded by 2 degrees, it was found that isopropanol/gasoline blends emitted lower NOx emissions than those at original spark timing. Isopropanol blends also increased the in-cylinder pressure values and heat release rate values.

  14. Enhancing the understanding of earthworm feeding behaviour via the use of fatty acid delta13C values determined by gas chromatography-combustion-isotope ratio mass spectrometry.

    Science.gov (United States)

    Dungait, Jennifer A J; Briones, Maria J I; Bol, Roland; Evershed, Richard P

    2008-06-01

    Litter-dwelling (epigeic) Lumbricus rubellus and soil-dwelling (endogeic) Allolobophora chlorotica earthworms were observed aggregating under C(3) (delta(13)C = -31.3 per thousand; delta(15)N = 10.7 per thousand) and C(4) (delta(13)C = -12.6 per thousand; delta(15)N = 7.5 per thousand) synthetic dung pats applied to a temperate grassland (delta(13)C = -30.3 per thousand; delta(15)N = 5.7 per thousand) in an experiment carried out for 372 days. Bulk delta(13)C values of earthworms collected from beneath either C(3) or C(4) dung after 28, 56, 112 and 372 days demonstrated that (i) L. rubellus beneath C(4) dung were significantly (13)C-enriched after 56 days (delta(13)C = -23.8 per thousand) and 112 days (delta(13)C = -22.4 per thousand) compared with those from C(3) dung treatments (56 days, delta(13)C = -26.5 per thousand; 112 days, delta(13)C = -27.0 per thousand), and (ii) A. chlorotica were 2.1 per thousand (13)C-enriched (delta(13)C = -24.2 per thousand) relative to those from C(3) dung (delta(13)C = -26.3 per thousand) treatments after 372 days. Bulk delta(15)N values did not suggest significant uptake of dung N by either species beneath C(3) or C(4) dung, but showed that the endogeic species (total mean delta(15)N = 3.3 per thousand) had higher delta(15)N values than the epigeic species (total mean delta(15)N = 5.4 per thousand). Although the two species exhibited similar fatty acid profiles, individual fatty acid delta(13)C values revealed extensive routing of dietary C into body tissue of L. rubellus, but minor incorporation into A. chlorotica. In particular, the direct incorporation of microbial biomarker fatty acids (iC(17:0), aC(17:0)) from (13)C-labelled dung in situ, the routing of dung C into de novo synthesised compounds (iC(20:4)(omega)(6),C(20:5)(omega)(3), and the assimilation of essential fatty acids ((C(18:1)(omega)(9), C(18:1)(omega(7), C(18:2)(omega(6), C(18:3)(omega)(3)) derived from dung, were determined. John Wiley & Sons, Ltd

  15. Amphetamines analysis in wastewaters - method performance of solid phase extraction - higher performance liquid chromatography mass spectrometry techniques (SPE-HPLC MS/MS)

    Science.gov (United States)

    Mustapha, Aliru Olajide; Ajao, Usman L

    2011-01-01

    Recently, many articles have reported different levels and distribution of amphetamine hitherto detected in biological fluids now appreciably found in aquatic environment at ng/L levels. Identification and measurement of amphetamine and its metabolites in surface and sewage waters using higher performance liquid chromatographic methodologies in the literatures now on current trend have provided information that are of scientific interest and effectively replaced immunological methods which only suggest the presence of these substances. Active research on both distribution and impacts of this important drug of abuse and related metabolites in the wastewaters are on-going. PMID:27857670

  16. The value of energy spectral CT in the differential diagnosis between benign and malignant soft tissue masses of the musculoskeletal system

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Xin [Department of Radiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong (China); Shao, Xiaodong [Department of Radiology, Qingdao Municipal Hospital, Qingdao, Shandong (China); Chen, Haisong, E-mail: chsEJR@163.com [Department of Radiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong (China)

    2015-06-15

    Highlights: • Different types of tissues have different types of spectral curves. • We find that spectral curve is useful in the differential diagnosis of benign and malignant tumor of the musculoskeletal system. • Arc shaped curve is a specific sign for tumors containing abundant fat. - Abstract: Objective: To explore the value of energy spectral CT in the differential diagnosis between benign and malignant tumor of the musculoskeletal system. Methods: Energy spectral CT scan was performed on 100 patients with soft tissue mass caused by musculoskeletal tumors found by MRI. Solid areas with homogenous density were chosen as region of interests (ROI), avoiding necrosis, hemorrhage and calcification region. Select the optimal keV on single energy images, and then the keV–CT curve was automatically generated. All 100 cases of tumors proved by histological examination were divided into four groups, 38 cases were in benign group, 10 cases in borderline group, 49 cases in malignant group, and 3 cases of lipoma (that were analyzed separately since its curve was arc shaped, significantly different from other curves). The formula used to calculate the slope of spectral curve was as follows: slope = (Hu40 keV − Hu80 keV)/40. As the slope was steep within the range of 40–80 keV based on preliminary observations, 40 keV and 80 keV were used as the reference points to calculate the slope value of the energy spectral curve. Kruskal–Wallis rank sum test was applied for statistical analysis, and P < 0.05 was considered to indicate a statistically significant difference. Results: The spectral curve of benign group was gradually falling type with a mean slope of 0.75 ± 0.30, that of malignant group was sharply falling type with a mean slope of 1.64 ± 1.00, and that of borderline group was a falling type between the above two groups with a mean slope of 1.34 ± 0.45. The differences of slopes between benign and malignant group, benign and borderline group were of

  17. [Estimation of the population attributable fraction due to obesity in hospital admissions for flu valued according to Body Mass Index (BMI) and CUN-BAE].

    Science.gov (United States)

    Dávila-Batista, V; Carriedo, D; Díez, F; Pueyo Bastida, A; Martínez Durán, B; Martin, V

    2018-03-01

    The obesity pandemic together with the influenza pandemic could lead to a significant burden of disease. The body mass index (BMI) does not discriminate obesity appropriately. The CUN-BAE has recently been used as an estimate of body fatness for Caucasians, including BMI, gender, and age. The aim of this study is to assess the population attributable fraction of hospital admissions due to influenza, due to the body fatness measured with the BMI, and the CUN-BAE. A multicentre study was conducted using matched case-controls. Cases were hospital admissions with the influenza confirmed by the RT-PCR method between 2009 and 2011. The risk of hospital admission and the population attribuible fraction were calculated using the BMI or the CUN-BAE for each adiposity category in a conditional logical regression analysis adjusted for confounding variables. The analyzes were estimated in the total sample, in unvaccinated people, and those less than 65 years-old. A total of 472 hospitalised cases and 493 controls were included in the study. Compared to normal weight, the aOR of influenza hospital admissions increases with each level of BMI (aOR=1.26; 2.06 and 11.64) and CUN-BAE (aOR=2.78; 4.29; 5.43 and 15.18). The population attributable fraction of influenza admissions using CUN-BAE is 3 times higher than that estimated with BMI (0,72 vs. 0,27), with the differences found being similar the non-vaccinated and under 65 year-olds. The BMI could be underestimating the burden of disease attributable to obesity in individuals hospitalised with influenza. There needs to be an appropriate assessment of the impact of obesity and vaccine recommendation criteria. Copyright © 2017 Sociedad Española de Médicos de Atención Primaria (SEMERGEN). Publicado por Elsevier España, S.L.U. All rights reserved.

  18. Higher Mediterranean Diet Quality Scores and Lower Body Mass Index Are Associated with a Less-Oxidized Plasma Glutathione and Cysteine Redox Status in Adults.

    Science.gov (United States)

    Bettermann, Erika L; Hartman, Terryl J; Easley, Kirk A; Ferranti, Erin P; Jones, Dean P; Quyyumi, Arshed A; Vaccarino, Viola; Ziegler, Thomas R; Alvarez, Jessica A

    2018-02-01

    Both systemic redox status and diet quality are associated with risk outcomes in chronic disease. It is not known, however, the extent to which diet quality influences plasma thiol/disulfide redox status. The purpose of this study was to investigate the influence of diet, as measured by diet quality scores and other dietary factors, on systemic thiol/disulfide redox status. We performed a cross-sectional study of 685 working men and women (ages ≥18 y) in Atlanta, GA. Diet was assessed by 3 diet quality scores: the Alternative Healthy Eating Index (AHEI), Dietary Approaches to Stop Hypertension (DASH), and the Mediterranean Diet Score (MDS). We measured concentrations of plasma glutathione (GSH), cysteine, their associated oxidized forms [glutathione disulfide (GSSG) and cystine (CySS), respectively], and their redox potentials (EhGSSG and EhCySS) to determine thiol/disulfide redox status. Linear regression modeling was performed to assess relations between diet and plasma redox after adjustment for age, body mass index (BMI), sex, race, and history of chronic disease. MDS was positively associated with plasma GSH (β = 0.02; 95% CI: 0.003, 0.03) and total GSH (GSH + GSSG) (β = 0.02; 95% CI: 0.003, 0.03), and inversely associated with the CySS:GSH ratio (β = -0.02; 95% CI: -0.04, -0.004). There were significant independent associations between individual MDS components (dairy, vegetables, fish, and monounsaturated fat intake) and varying plasma redox indexes (P indexes and other diet factors of interest were not significantly correlated with plasma thiol and disulfide redox measures. Adherence to the Mediterranean diet was significantly associated with a favorable plasma thiol/disulfide redox profile, independent of BMI, in a generally healthy working adult population. Although longitudinal studies are warranted, these findings contribute to the feasibility of targeting a Mediterranean diet to improve plasma redox status.

  19. On the experimental value of the DELTA sup + (1232) mass from gamma p -> n pi sup + (p suppi sup 0) reactions

    CERN Document Server

    Omelaenko, A S

    2002-01-01

    The reliability of the phenomenological estimates for the DELTA sup + (1232) mass is questioned coming from the of pi sup + and pi sup 0 mesons photoproduction data off proton target till the end of 2001. The origin of an old discrepancy for the DELTA sup + (1232) mass presented in tables of the Particle Data Group is discussed.

  20. Disconnected quark loop contributions to nucleon observables using Nf=2 twisted clover fermions at the physical value of the light quark mass

    International Nuclear Information System (INIS)

    Abdel-Rehim, Abdou; Kallidonis, Christos; Koutsou, Giannis

    2015-11-01

    We compute the disconnected quark loops contributions entering the determination of nucleon observables, by using a N f =2 ensemble of twisted mass fermions with a clover term at a pion mass m π =133 MeV. We employ exact deflation and implement all calculations in GPUs, enabling us to achieve large statistics and a good signal.

  1. Disconnected quark loop contributions to nucleon observables using N{sub f}=2 twisted clover fermions at the physical value of the light quark mass

    Energy Technology Data Exchange (ETDEWEB)

    Abdel-Rehim, Abdou; Kallidonis, Christos; Koutsou, Giannis [Cyprus Institute, Nicosia (Cyprus). Computation-based Science and Technology Research Center; Alexandrou, Constantia; Constantinou, Martha; Hadjiyiannakou, Kyriakos [Cyprus Institute, Nicosia (Cyprus). Computation-based Science and Technology Research Center; Cyprus Univ. (Cyprus). Dept. of Physics; Jansen, Karl [DESY Zeuthen (Germany). NIC; Aviles-Casco, Alejandro Vaquero [INFN Sezione di Milano-Bicocca, Milano (Italy)

    2015-11-15

    We compute the disconnected quark loops contributions entering the determination of nucleon observables, by using a N{sub f}=2 ensemble of twisted mass fermions with a clover term at a pion mass m{sub π}=133 MeV. We employ exact deflation and implement all calculations in GPUs, enabling us to achieve large statistics and a good signal.

  2. The association between higher maternal pre-pregnancy body mass index and increased birth weight, adiposity and inflammation in the newborn.

    Science.gov (United States)

    McCloskey, K; Ponsonby, A-L; Collier, F; Allen, K; Tang, M L K; Carlin, J B; Saffery, R; Skilton, M R; Cheung, M; Ranganathan, S; Dwyer, T; Burgner, D; Vuillermin, P

    2018-01-01

    Excess adiposity and adiposity-related inflammation are known risk factors for cardiovascular disease in adults; however, little is known regarding the determinants of adiposity-related inflammation at birth. The aim of this study was to investigate the association between maternal pre-pregnancy BMI and newborn adiposity and inflammation. Paired maternal (28-week gestation) and infant (umbilical cord) blood samples were collected from a population-derived birth cohort (Barwon Infant Study, n = 1074). Data on maternal comorbidities and infant birth anthropomorphic measures were compiled, and infant aortic intima-media thickness was measured by trans-abdominal ultrasound. In a selected subgroup of term infants (n = 161), matched maternal and cord lipids, high-sensitivity C-reactive protein (hsCRP) and maternal soluble CD14 were measured. Analysis was completed by using pairwise correlation and linear regression. Because of their non-normal distribution, pathology blood measures were log transformed prior to analysis. Maternal pre-pregnancy BMI was positively associated with increased birth weight (mean difference 17.8 g per kg m -2 , 95% CI 6.6 to 28.9; p = 0.002), newborn mean skin-fold thickness (mean difference 0.1 mm per kg m -2 , 95% CI 0.0 to 0.1; p pregnancy BMI, 95% CI 0.6 to 7.7%, p = 0.02), but not cord blood soluble CD14. Inclusion of maternal hsCRP as a covariate attenuated the associations between pre-pregnancy BMI and both newborn skin-fold thickness and cord blood hsCRP. Higher maternal pre-pregnancy BMI is associated with increased newborn adiposity and inflammation. These associations may be partially mediated by maternal inflammation during pregnancy. © 2016 World Obesity Federation.

  3. Boundaries of mass resolution in native mass spectrometry.

    Science.gov (United States)

    Lössl, Philip; Snijder, Joost; Heck, Albert J R

    2014-06-01

    Over the last two decades, native mass spectrometry (MS) has emerged as a valuable tool to study intact proteins and noncovalent protein complexes. Studied experimental systems range from small-molecule (drug)-protein interactions, to nanomachineries such as the proteasome and ribosome, to even virus assembly. In native MS, ions attain high m/z values, requiring special mass analyzers for their detection. Depending on the particular mass analyzer used, instrumental mass resolution does often decrease at higher m/z but can still be above a couple of thousand at m/z 5000. However, the mass resolving power obtained on charge states of protein complexes in this m/z region is experimentally found to remain well below the inherent instrument resolution of the mass analyzers employed. Here, we inquire into reasons for this discrepancy and ask how native MS would benefit from higher instrumental mass resolution. To answer this question, we discuss advantages and shortcomings of mass analyzers used to study intact biomolecules and biomolecular complexes in their native state, and we review which other factors determine mass resolving power in native MS analyses. Recent examples from the literature are given to illustrate the current status and limitations.

  4. Efficacy of adjuvant therapy with 3.7 GBq radioactive iodine in intermediate-risk patients with 'higher risk features' and predictive value of postoperative nonstimulated thyroglobulin.

    Science.gov (United States)

    Rosario, Pedro W; Mourão, Gabriela F; Calsolari, Maria Regina

    2016-11-01

    This study evaluated the efficacy of adjuvant therapy with 3.7 GBq radioactive iodine (RAI) in patients with papillary thyroid carcinoma (PTC) of intermediate risk with higher risk features and determined the predictive value of postoperative nonstimulated thyroglobulin (Tg). This was a prospective study including 85 patients with PTC of intermediate risk and higher risk features: tumor greater than 1 cm and aggressive histological subtype or vascular invasion; and/or more than three positive lymph node (LN) or LN greater than 1.5 cm or showing macroscopic extracapsular extension; and/or a combination of tumor greater than 4 cm, microscopic extrathyroidal extension, aggressive histology, and LN metastases (cN1). After thyroidectomy, all patients had nonstimulated Tg of at least 0.3 ng/ml and ultrasonography showed no anomalies. When evaluated 12 months after RAI therapy, an excellent response to initial therapy was achieved in 61 patients (71.7%). Structural disease was detected in five patients (5.9%). During follow-up, 6/80 patients (7.5%) without structural disease 1 year after RAI developed relapse. In the last assessment, 80 patients (94.1%) had nonstimulated Tg less than 1 ng/ml and no evidence of structural disease. There was no case of death because of the tumor. Postoperative nonstimulated Tg was a predictive factor of the main outcome (structural disease 1 year after RAI or recurrence) and the best cut-off was 1.8 ng/ml (sensitivity: 72.7%, specificity: 83.4%, negative predictive value: 95.4%). In patients with PTC of intermediate risk with higher risk features treated with 3.7 GBq RAI, postoperative nonstimulated Tg up to 1.8 ng/ml was a predictor of low risk of structural disease 1 year after therapy or recurrence.

  5. «A Mighty Weapon in the Class War»: Proletarian Values, Tourism and Mass Mobilisation in Stalin’s Time

    NARCIS (Netherlands)

    Noack, C.

    2012-01-01

    The article contextualises the 1920s Soviet project of «proletarian» tourism in contemporary debates on mass cultural politics. Juxtaposed both to established Western and Soviet practices, the project of «proletarian» tourism tried to bridge the gap between self-organised, «grass-roots» tourism and

  6. Higher Education

    African Journals Online (AJOL)

    Kunle Amuwo: Higher Education Transformation: A Paradigm Shilt in South Africa? ... ty of such skills, especially at the middle management levels within the higher ... istics and virtues of differentiation and diversity. .... may be forced to close shop for lack of capacity to attract ..... necessarily lead to racial and gender equity,.

  7. Mass spectroscopy investigation of the effect of gamma irradiation on the mean value of the number of ethoxy groups in the triton X-100

    International Nuclear Information System (INIS)

    Valdés Díaz, Gilmer; Rodríguez Calvo, Simón; Pérez Gramatges, Aurora; Fernández Lima, Francisco Alberto; Rapado Paneque, Manuel; Ponciano, Cassia Ribero R.; Frota da Silveira, Enio

    2007-01-01

    The effect of gamma radiation from a 60 Co source on the structure of a nonionic surfactant, namely TRITON X-100, was investigated. Three main regions can be distinguished in the behavior of the mean value of ethoxy groups with an increase in the absorbed dose. However just a slightly decrease on this mean value was obtained when the dose range from 0 to 70 kGy. (author)

  8. Higher Education

    Science.gov (United States)

    & Development (LDRD) National Security Education Center (NSEC) Office of Science Programs Richard P Databases National Security Education Center (NSEC) Center for Nonlinear Studies Engineering Institute Scholarships STEM Education Programs Teachers (K-12) Students (K-12) Higher Education Regional Education

  9. Valuing Essays: Essaying Values

    Science.gov (United States)

    Badley, Graham

    2010-01-01

    The essay regularly comes under attack. It is criticised for being rigidly linear rather than flexible and reflective. I first challenge this view by examining reasons why the essay should be valued as an important genre. Secondly, I propose that in using the essay form students and academics necessarily exemplify their own critical values. Essays…

  10. Can the Discrepancy between Locally and Globally Derived Neutral Hydrogen Mass Functions be Explained by a Varying Value of M ⋆?

    Science.gov (United States)

    Minchin, Robert F.

    2017-09-01

    I investigate whether it is possible to reconcile the recent Arecibo Legacy Fast Arecibo L-band Feed Array (ALFALFA) observation that the neutral hydrogen mass function (HIMF) across different galactic densities has the same, non-flat, faint-end slope, with observations of isolated galaxies and many galaxy groups that show their HIMFs to have flat faint-end slopes. I find that a fairly simple model in which the position of the knee in the mass function of each individual group is allowed to vary is able to account for both of these observations. If this model reflects reality, the ALFALFA results point to an interesting “conspiracy” whereby the differing group HIMFs always sum up to form global HIMFs with the same faint-end slope in different environments. More generally, this result implies that global environmental HIMFs do not necessarily reflect the HIMFs in individual groups belonging to that environment and cannot be used to directly measure variations in group-specific HIMFs with environment.

  11. Can the Discrepancy between Locally and Globally Derived Neutral Hydrogen Mass Functions be Explained by a Varying Value of M {sup *}?

    Energy Technology Data Exchange (ETDEWEB)

    Minchin, Robert F., E-mail: rminchin@naic.edu [Arecibo Observatory, Universities Space Research Association, HC3 Box 53995, Arecibo, PR 00612 (United States)

    2017-09-20

    I investigate whether it is possible to reconcile the recent Arecibo Legacy Fast Arecibo L-band Feed Array (ALFALFA) observation that the neutral hydrogen mass function (HIMF) across different galactic densities has the same, non-flat, faint-end slope, with observations of isolated galaxies and many galaxy groups that show their HIMFs to have flat faint-end slopes. I find that a fairly simple model in which the position of the knee in the mass function of each individual group is allowed to vary is able to account for both of these observations. If this model reflects reality, the ALFALFA results point to an interesting “conspiracy” whereby the differing group HIMFs always sum up to form global HIMFs with the same faint-end slope in different environments. More generally, this result implies that global environmental HIMFs do not necessarily reflect the HIMFs in individual groups belonging to that environment and cannot be used to directly measure variations in group-specific HIMFs with environment.

  12. Spatial correlation between the predictor variables and the weighting values calculated during the mapping of the environmental factors of mass movements in the Beni Idder region (northern Rif

    Directory of Open Access Journals (Sweden)

    Ait Brahim L.

    2018-01-01

    Full Text Available The Tleta of Beni Ider region located in the SW of Tetouan (Rif Septentrional knows many mass instabilities. The diagnostic via the inventory, the mapping and the characterization of mass movements was made by using satellite imagery, aerial photography and field data coupled with existing documents (geological, geomorphological,…. The understanding of both their spatial distribution and the mechanism generating them, is very complex because of the existence of an important number of natural factors (geological, geomorphological, hydrological in a relative mountainous landscape with deep valleys, steep slopes and significant elevation changes. Thus, a multidisciplinary approach was adopted to elaborate the landslide susceptibility map of the region taking into account interactions and causal relationships between the various natural parameters that tend to accentuate and aggravate the setting of landslides. The multidisciplinary database allowed us to evaluate the susceptibility thanks to a bivariate probabiliste model (Weight of Evidence. The obtained landslide susceptibility map is a major contribution to the development of urban development plans in the region.

  13. Higher Education.

    Science.gov (United States)

    Hendrickson, Robert M.

    This chapter reports 1982 cases involving aspects of higher education. Interesting cases noted dealt with the federal government's authority to regulate state employees' retirement and raised the questions of whether Title IX covers employment, whether financial aid makes a college a program under Title IX, and whether sex segregated mortality…

  14. Measuring and valuing convenience and service quality: A review of global practices and challenges from mass transit operators and railway industries

    OpenAIRE

    Anderson, Richard; Condry, Benjamin; Findlay, Nicholas; Brage-Ardao, Ruben; Li, Haojie

    2013-01-01

    Origin-destination demand, trip patterns, pricing and transport networks alone cannot explain passenger demand for public transport modes. Other factors of convenience and service quality play a key role in influencing demand and mode choice but they are often more complex and harder to define, measure and value. This paper argues that the good measurement of public transport convenience and service quality is a pre-requisite to its valuation and ensuring more optimal policy and management ac...

  15. Higher body mass index in 16-19 year-old Jewish Adolescents of North African, Middle Eastern and European Origins is a Predictor of Acute Myeloid Leukemia: a cohort of 2.3 million Israelis.

    Science.gov (United States)

    Shamriz, Oded; Leiba, Merav; Levine, Hagai; Derazne, Estela; Keinan-Boker, Lital; Kark, Jeremy D

    2017-04-01

    Studies evaluating adolescent risk factors for developing acute myeloid leukemia (AML) are virtually nonexistent. We assessed adolescent predictors of AML in adults, with a main focus on adolescent BMI. The study included 2,310,922 16-19-year-old Jewish Israeli adolescents (mean age 17.3 ± 0.4, 59.5% male), called up for an obligatory health examination. Sociodemographic and health data, including measured weight and height, were gathered. Body mass index (BMI) was examined both as a continuous variable and grouped according to the World Health Organization (WHO) classification and US-CDC percentiles. Bone-marrow-biopsy-verified AML cases diagnosed up to 31 December 2012 were identified by linkage to the Israel national cancer registry. Multivariable-adjusted Cox proportional-hazards models were used to model time to diagnosis. During 47 million person years of follow-up, 568 AML cases were identified (crude incidence rate 1.21/100,000 person years). There was a multivariable-adjusted hazard ratio (HR) of 1.041 (95% CI 1.015-1.068, p = 0.002) per unit BMI. The association was evident in those of Middle Eastern, North African, and European origin. A graded association was evident across the overweight and obese WHO grouping. With the US-CDC grouping, excess risk was evident in overweight but not in obese adolescents, although a test for trend in percentiles was significant (p = 0.004). Borderline associations were noted for origin (p = 0.065) (higher in the predominantly Ashkenazi European origin), sex (higher in women: HR = 1.24 (95% CI 0.99-1.55), and stature (HR = 1.013, 95% CI 1.000-1.026, per cm). Higher BMI in adolescence was associated with increased AML incidence in adulthood in this multiethnic population.

  16. Fluid-Elastic Instability Tests on Parallel Triangular Tube Bundles with Different Mass Ratio Values under Increasing and Decreasing Flow Velocities

    Directory of Open Access Journals (Sweden)

    Xu Zhang

    2016-01-01

    Full Text Available To study the effects of increasing and decreasing flow velocities on the fluid-elastic instability of tube bundles, the responses of an elastically mounted tube in a rigid parallel triangular tube bundle with a pitch-to-diameter ratio of 1.67 were tested in a water tunnel subjected to crossflow. Aluminum and stainless steel tubes were tested, respectively. In the in-line and transverse directions, the amplitudes, power spectrum density functions, response frequencies, added mass coefficients, and other results were obtained and compared. Results show that the nonlinear hysteresis phenomenon occurred in both tube bundle vibrations. When the flow velocity is decreasing, the tubes which have been in the state of fluid-elastic instability can keep on this state for a certain flow velocity range. During this process, the response frequencies of the tubes will decrease. Furthermore, the response frequencies of the aluminum tube can decrease much more than those of the stainless steel tube. The fluid-elastic instability constants fitted for these experiments were obtained from experimental data. A deeper insight into the fluid-elastic instability of tube bundles was also obtained by synthesizing the results. This study is beneficial for designing and operating equipment with tube bundles inside, as well as for further research on the fluid-elastic instability of tube bundles.

  17. Higher Education in Scandinavia

    DEFF Research Database (Denmark)

    Nielsen, Jørgen Lerche; Andreasen, Lars Birch

    2015-01-01

    Higher education systems around the world have been undergoing fundamental changes through the last 50 years from more narrow self-sustaining universities for the elite and into mass universities, where new groups of students have been recruited and the number of students enrolled has increased...... an impact on the educational systems in Scandinavia, and what possible futures can be envisioned?...... dramatically. In adjusting to the role of being a mass educational institution, universities have been challenged on how to cope with external pressures, such as forces of globalization and international markets, increased national and international competition for students and research grants, increased...

  18. Positive predictive value between medical-chart body-mass-index category and obesity versus codes in a claims-data warehouse.

    Science.gov (United States)

    Caplan, Eleanor O; Kamble, Pravin S; Harvey, Raymond A; Smolarz, B Gabriel; Renda, Andrew; Bouchard, Jonathan R; Huang, Joanna C

    2018-01-01

    To evaluate the positive predictive value of claims-based V85 codes for identifying individuals with varying degrees of BMI relative to their measured BMI obtained from medical record abstraction. This was a retrospective validation study utilizing administrative claims and medical chart data from 1 January 2009 to 31 August 2015. Randomly selected samples of patients enrolled in a Medicare Advantage Prescription Drug (MAPD) or commercial health plan and with a V85 claim were identified. The claims-based BMI category (underweight, normal weight, overweight, obese class I-III) was determined via corresponding V85 codes and compared to the BMI category derived from chart abstracted height, weight and/or BMI. The positive predictive values (PPVs) of the claims-based BMI categories were calculated with the corresponding 95% confidence intervals (CIs). The overall PPVs (95% CIs) in the MAPD and commercial samples were 90.3% (86.3%-94.4%) and 91.1% (87.3%-94.9%), respectively. In each BMI category, the PPVs (95% CIs) for the MAPD and commercial samples, respectively, were: underweight, 71.0% (55.0%-87.0%) and 75.9% (60.3%-91.4%); normal, 93.8% (85.4%-100%) and 87.8% (77.8%-97.8%); overweight, 97.4% (92.5%-100%) and 93.5% (84.9%-100%); obese class I, 96.9 (90.9%-100%) and 97.2% (91.9%-100%); obese class II, 97.0% (91.1%-100%) and 93.0% (85.4%-100%); and obese class III, 85.0% (73.3%-96.1%) and 97.1% (91.4%-100%). BMI categories derived from administrative claims, when available, can be used successfully particularly in the context of obesity research.

  19. The Value of Value

    DEFF Research Database (Denmark)

    Sørensen, Asger

    parts of business ethics given prominence to especially one term, namely `value'. The question that interests me is the following: What does the articulation of ethics and morality in terms of values mean for ethics and morality as such. Or, to put the question in a more fashionably way: What......As a social scientist of ethics and morality, Luhmann has noticed the ethical wave that has recently swept across the western world, and states that this particular kind of wave seems to have a wavelength of about one hundred years (cf. Luhmann 1989: 9 ff.). Even though the frequency...... and the regularity of such a phenomenon is both hard to verify and, if true, difficult to explain, it seems fair to say that since the Enlightenment, an approaching fin-de-siecle has brought an increased interest in matters concerning morality and ethics.1 The present peak has in public-political discourse and some...

  20. The value of calcaneal bone mass measurement using a dual X-ray laser calscan device in risk screening for osteoporosis

    Directory of Open Access Journals (Sweden)

    Gulseren Kayalar

    2009-01-01

    Full Text Available OBJECTIVE: To evaluate how bone mineral density in the calcaneus measured by a dual energy X-ray laser (DXL correlates with bone mineral density in the spine and hip in Turkish women over 40 years of age and to determine whether calcaneal dual energy X-ray laser variables are associated with clinical risk factors to the same extent as axial bone mineral density measurements obtained using dual energy x-ray absorbtiometry (DXA. MATERIALS AND METHODS: A total of 2,884 Turkish women, aged 40-90 years, living in Ankara were randomly selected. Calcaneal bone mineral density was evaluated using a dual energy X-ray laser Calscan device. Subjects exhibiting a calcaneal dual energy X-ray laser T- score <-2.5 received a referral for DXA of the spine and hip. Besides dual energy X-ray laser measurements, all subjects were questioned about their medical history and the most relevant risk factors for osteoporosis. RESULTS: Using a T-score threshold of -2.5, which is recommended by the World Health Organization (WHO, dual energy X-ray laser calcaneal measurements showed that 13% of the subjects had osteoporosis, while another 56% had osteopenia. The mean calcaneal dual energy X-ray laser T-score of postmenopausal subjects who were smokers with a positive history of fracture, hormone replacement therapy (HRT, covered dressing style, lower educational level, no regular exercise habits, and low tea consumption was significantly lower than that obtained for the other group (p<0.05. A significant correlation was observed between the calcaneal dual energy X-ray laser T-score and age (r=-0.465, p=0.001, body mass index (BMI (r=0.223, p=0.001, number of live births (r=-0.229, p=0.001, breast feeding time (r=-0.064, p=0.001, and age at menarche (r=-0.050, p=0.008. The correlations between calcaneal DXL and DXA T-scores (r=0.340, p=0.001 and calcaneal DXL and DXA Z-scores (r=0.360, p=0.001 at the spine, and calcaneal DXL and DXA T- scores (r=0.28, p=0.001 and calcaneal

  1. Comparison of liquid chromatography-isotope ratio mass spectrometry (LC/IRMS) and gas chromatography-combustion-isotope ratio mass spectrometry (GC/C/IRMS) for the determination of collagen amino acid δ13C values for palaeodietary and palaeoecological reconstruction.

    Science.gov (United States)

    Dunn, Philip J H; Honch, Noah V; Evershed, Richard P

    2011-10-30

    Results are presented of a comparison of the amino acid (AA) δ(13)C values obtained by gas chromatography-combustion-isotope ratio mass spectrometry (GC/C/IRMS) and liquid chromatography-isotope ratio mass spectrometry (LC/IRMS). Although the primary focus was the compound-specific stable carbon isotope analysis of bone collagen AAs, because of its growing application for palaeodietary and palaeoecological reconstruction, the results are relevant to any field where AA δ(13)C values are required. We compare LC/IRMS with the most up-to-date GC/C/IRMS method using N-acetyl methyl ester (NACME) AA derivatives. This comparison involves the analysis of standard AAs and hydrolysates of archaeological human bone collagen, which have been previously investigated as N-trifluoroacetyl isopropyl esters (TFA/IP). It was observed that, although GC/C/IRMS analyses required less sample, LC/IRMS permitted the analysis of a wider range of AAs, particularly those not amenable to GC analysis (e.g. arginine). Accordingly, reconstructed bulk δ(13)C values based on LC/IRMS-derived δ(13)C values were closer to the EA/IRMS-derived δ(13)C values than those based on GC/C/IRMS values. The analytical errors for LC/IRMS AA δ(13)C values were lower than GC/C/IRMS determinations. Inconsistencies in the δ(13)C values of the TFA/IP derivatives compared with the NACME- and LC/IRMS-derived δ(13)C values suggest inherent problems with the use of TFA/IP derivatives, resulting from: (i) inefficient sample combustion, and/or (ii) differences in the intra-molecular distribution of δ(13)C values between AAs, which are manifested by incomplete combustion. Close similarities between the NACME AA δ(13)C values and the LC/IRMS-derived δ(13)C values suggest that the TFA/IP derivatives should be abandoned for the natural abundance determinations of AA δ(13)C values. Copyright © 2011 John Wiley & Sons, Ltd.

  2. Can adaptive threshold-based metabolic tumor volume (MTV) and lean body mass corrected standard uptake value (SUL) predict prognosis in head and neck cancer patients treated with definitive radiotherapy/chemoradiotherapy?

    Science.gov (United States)

    Akagunduz, Ozlem Ozkaya; Savas, Recep; Yalman, Deniz; Kocacelebi, Kenan; Esassolak, Mustafa

    2015-11-01

    To evaluate the predictive value of adaptive threshold-based metabolic tumor volume (MTV), maximum standardized uptake value (SUVmax) and maximum lean body mass corrected SUV (SULmax) measured on pretreatment positron emission tomography and computed tomography (PET/CT) imaging in head and neck cancer patients treated with definitive radiotherapy/chemoradiotherapy. Pretreatment PET/CT of the 62 patients with locally advanced head and neck cancer who were treated consecutively between May 2010 and February 2013 were reviewed retrospectively. The maximum FDG uptake of the primary tumor was defined according to SUVmax and SULmax. Multiple threshold levels between 60% and 10% of the SUVmax and SULmax were tested with intervals of 5% to 10% in order to define the most suitable threshold value for the metabolic activity of each patient's tumor (adaptive threshold). MTV was calculated according to this value. We evaluated the relationship of mean values of MTV, SUVmax and SULmax with treatment response, local recurrence, distant metastasis and disease-related death. Receiver-operating characteristic (ROC) curve analysis was done to obtain optimal predictive cut-off values for MTV and SULmax which were found to have a predictive value. Local recurrence-free (LRFS), disease-free (DFS) and overall survival (OS) were examined according to these cut-offs. Forty six patients had complete response, 15 had partial response, and 1 had stable disease 6 weeks after the completion of treatment. Median follow-up of the entire cohort was 18 months. Of 46 complete responders 10 had local recurrence, and of 16 partial or no responders 10 had local progression. Eighteen patients died. Adaptive threshold-based MTV had significant predictive value for treatment response (p=0.011), local recurrence/progression (p=0.050), and disease-related death (p=0.024). SULmax had a predictive value for local recurrence/progression (p=0.030). ROC curves analysis revealed a cut-off value of 14.00 mL for

  3. Repurposing Mass-produced Internal Combustion Engines Quantifying the Value and Use of Low-cost Internal Combustion Piston Engines for Modular Applications in Energy and Chemical Engineering Industries

    Science.gov (United States)

    L'Heureux, Zara E.

    This thesis proposes that internal combustion piston engines can help clear the way for a transformation in the energy, chemical, and refining industries that is akin to the transition computer technology experienced with the shift from large mainframes to small personal computers and large farms of individually small, modular processing units. This thesis provides a mathematical foundation, multi-dimensional optimizations, experimental results, an engine model, and a techno-economic assessment, all working towards quantifying the value of repurposing internal combustion piston engines for new applications in modular, small-scale technologies, particularly for energy and chemical engineering systems. Many chemical engineering and power generation industries have focused on increasing individual unit sizes and centralizing production. This "bigger is better" concept makes it difficult to evolve and incorporate change. Large systems are often designed with long lifetimes, incorporate innovation slowly, and necessitate high upfront investment costs. Breaking away from this cycle is essential for promoting change, especially change happening quickly in the energy and chemical engineering industries. The ability to evolve during a system's lifetime provides a competitive advantage in a field dominated by large and often very old equipment that cannot respond to technology change. This thesis specifically highlights the value of small, mass-manufactured internal combustion piston engines retrofitted to participate in non-automotive system designs. The applications are unconventional and stem first from the observation that, when normalized by power output, internal combustion engines are one hundred times less expensive than conventional, large power plants. This cost disparity motivated a look at scaling laws to determine if scaling across both individual unit size and number of units produced would predict the two order of magnitude difference seen here. For the first

  4. High-precision measurement of phenylalanine δ15N values for environmental samples: a new approach coupling high-pressure liquid chromatography purification and elemental analyzer isotope ratio mass spectrometry.

    Science.gov (United States)

    Broek, Taylor A B; Walker, Brett D; Andreasen, Dyke H; McCarthy, Matthew D

    2013-11-15

    Compound-specific isotope analysis of individual amino acids (CSI-AA) is a powerful new tool for tracing nitrogen (N) source and transformation in biogeochemical cycles. Specifically, the δ(15)N value of phenylalanine (δ(15)N(Phe)) represents an increasingly used proxy for source δ(15)N signatures, with particular promise for paleoceanographic applications. However, current derivatization/gas chromatography methods require expensive and relatively uncommon instrumentation, and have relatively low precision, making many potential applications impractical. A new offline approach has been developed for high-precision δ(15)N measurements of amino acids (δ(15)N(AA)), optimized for δ(15)N(Phe) values. Amino acids (AAs) are first purified via high-pressure liquid chromatography (HPLC), using a mixed-phase column and automated fraction collection. The δ(15)N values are determined via offline elemental analyzer-isotope ratio mass spectrometry (EA-IRMS). The combined HPLC/EA-IRMS method separated most protein AAs with sufficient resolution to obtain accurate δ(15)N values, despite significant intra-peak isotopic fractionation. For δ(15)N(Phe) values, the precision was ±0.16‰ for standards, 4× better than gas chromatography/combustion/isotope ratio mass spectrometry (GC/C/IRMS; ±0.64‰). We also compared a δ(15)N(Phe) paleo-record from a deep-sea bamboo coral from Monterey Bay, CA, USA, using our method versus GC/C/IRMS. The two methods produced equivalent δ(15)N(Phe) values within error; however, the δ(15)N(Phe) values from HPLC/EA-IRMS had approximately twice the precision of GC/C/IRMS (average stdev of 0.27‰ ± 0.14‰ vs 0.60‰ ± 0.20‰, respectively). These results demonstrate that offline HPLC represents a viable alternative to traditional GC/C/IMRS for δ(15)N(AA) measurement. HPLC/EA-IRMS is more precise and widely available, and therefore useful in applications requiring increased precision for data interpretation (e.g. δ(15)N paleoproxies

  5. Estimated GFR and Subsequent Higher Left Ventricular Mass in Young and Middle-Aged Adults With Normal Kidney Function: The Coronary Artery Risk Development in Young Adults (CARDIA) Study.

    Science.gov (United States)

    Bansal, Nisha; Lin, Feng; Vittinghoff, Eric; Peralta, Carmen; Lima, Joao; Kramer, Holly; Shlipak, Michael; Bibbins-Domingo, Kirsten

    2016-02-01

    Left ventricular hypertrophy is common and is associated with cardiovascular events and death among patients with known chronic kidney disease. However, the link between reduced glomerular filtration rate (GFR) and left ventricular mass index (LVMI) remains poorly explored among young and middle-aged adults with preserved kidney function. In this study, we examined the association of cystatin C-based estimated GFR (eGFRcys) and rapid decline in eGFR with subsequent LVMI. Observational study. We included 2,410 participants from the Coronary Artery Risk Development in Young Adults (CARDIA) cohort with eGFRcys > 60mL/min/1.73m(2) at year 15 and who had an echocardiogram obtained at year 25. eGFRcys at year 15 and rapid decline in eGFRcys (defined as >3% per year over 5 years from years 15 to 20). LVMI measured at year 25. We adjusted for age, sex, race, diabetes, body mass index, low- and high-density lipoprotein cholesterol levels, cumulative systolic blood pressure, and albuminuria. Mean age was 40±4 (SD) years, 58% were women, and 43% were black. After 10 years of follow-up, mean LVMI was 39.6±13.4g/m(2.7). Compared with eGFRcys > 90mL/min/1.73m(2) (n = 2,228), eGFRcys of 60 to 75mL/min/1.73m(2) (n = 29) was associated with 5.63 (95% CI, 0.90-10.36) g/m(2.7) greater LVMI (P = 0.02), but there was no association of eGFRcys of 76 to 90mL/min/1.73m(2) (n = 153) with LVMI after adjustment for confounders. Rapid decline in eGFRcys was associated with higher LVMI compared with participants without a rapid eGFRcys decline (β coefficient, 1.48; 95% CI, 0.11-2.83; P = 0.03) after adjustment for confounders. There were a limited number of participants with eGFRcys of 60 to 90mL/min/1.73m(2). Among young and middle-aged adults with preserved kidney function, eGFRcys of 60 to 75mL/min/1.73m(2) and rapid decline in eGFRcys were significantly associated with subsequently higher LVMI. Further studies are needed to understand the mechanisms that contribute to elevated

  6. Correlates of increased lean muscle mass in women with polycystic ovary syndrome.

    Science.gov (United States)

    Carmina, E; Guastella, E; Longo, R A; Rini, G B; Lobo, R A

    2009-10-01

    Muscle mass plays an important role in determining cardiovascular and metabolic risks in polycystic ovary syndrome (PCOS). In addition, whether lean mass influences carotid intima-media thickness (IMT) in PCOS has not been assessed. Prospective investigation. Ninety-five women with PCOS were age- and weight-matched to 90 ovulatory controls. All women had dual X-ray absorptiometry for lean, fat and bone mass, and bone mass density (BMD). Serum testosterone, sex hormone-binding globulin, insulin, and glucose and carotid IMT were determined. Free androgen index (FAI) and insulin resistance (by QUICKI) were calculated. In PCOS, waist circumference and insulin were higher and QUICKI lower than in controls (Plean mass were higher in PCOS compared to controls (PPCOS (PPCOS patients had abnormal (> or = 0.9 mm) values. Lean mass correlated with fat parameters, insulin, QUICKI, and FAI, but not with total testosterone; and after adjustments for insulin and QUICKI, lean mass still correlated with fat mass (PLean mass correlated with IMT (Plean mass independently of insulin. Bone mass correlated with lean and fat mass, but not with insulin or androgen. PCOS patients with 'pathological' IMT values had higher % trunk fat, lean mass, and insulin, lower QUICKI, and higher testosterone and FAI compared with those with normal IMT. Lean mass is increased in PCOS, while bone mass is similar to that of matched controls. The major correlates of lean mass are fat mass and insulin but not androgen. Lean mass also correlated with IMT, and although influenced by insulin, small changes in IMT may partially reflect changes in muscle mass, while clearly abnormal values relate to more severe abnormalities of PCOS.

  7. Mass corrections in deep-inelastic scattering

    International Nuclear Information System (INIS)

    Gross, D.J.; Treiman, S.B.; Wilczek, F.A.

    1977-01-01

    The moment sum rules for deep-inelastic lepton scattering are expected for asymptotically free field theories to display a characteristic pattern of logarithmic departures from scaling at large enough Q 2 . In the large-Q 2 limit these patterns do not depend on hadron or quark masses m. For modest values of Q 2 one expects corrections at the level of powers of m 2 /Q 2 . We discuss the question whether these mass effects are accessible in perturbation theory, as applied to the twist-2 Wilson coefficients and more generally. Our conclusion is that some part of the mass effects must arise from a nonperturbative origin. We also discuss the corrections which arise from higher orders in perturbation theory for very large Q 2 , where mass effects can perhaps be ignored. The emphasis here is on a characterization of the Q 2 , x domain where higher-order corrections are likely to be unimportant

  8. Comparison and Association of Intellectual Capital: An Investigation and Measurement of the Value of Intellectual Capital Assets and Their Contribution to Stakeholder Perception within the Framework of Higher Education

    Science.gov (United States)

    Helm Stevens, Roxanne

    2011-01-01

    PROBLEM: Many of the preliminary approaches to strategic management of intellectual capital or knowledge assets have not been attempted in the not-for-profit arena. Additionally, because there is no marketplace value for not-for-profit firms or a valuation system for intangible assets, the identification and measurement necessary for efficient and…

  9. Professional and Social Media Sites (SMSs): Motives and Positive Values of Accommodating Social Media Sites (SMSs) in Teaching Practices according to Indonesian Professional Educators: A Case Study in Two Indonesian Higher Educational Institutions

    Science.gov (United States)

    Luke, J. Y.; Billy, Y. L.

    2017-09-01

    In millennium era, the proliferating Social Media Sites (SMSs) has not only brought increasing demands for all humans, but also creates positive values, specifically for the professional educators or lecturers in any ages. This study envisages the positive values of accommodating Social Media Sites (SMSs) in teaching practices according to the professional educators. Thirty professional educators, i.e. the lecturers, from two universities (i.e. Multimedia Nusantara University and Bina Nusantara University) has participated in this study. The data was collected from the survey by means of questionnaires, analysed using percentages, and exposed the results descriptively. The findings reflected that the positive values of accommodating Social Media Sites in teaching practices were to develop social skills and improve academic skills. However among the two values, the latter was highly influencing the professional educators because of the four reasons: enabling to do tutorial lessons, providing online discussion space with experts or guest lecturers, assisting in doing peer-review and peer-editing, and enhancing the receptive skills, the productive skills, and also the critical thinking skills of the users in SMSs, especially the professional educators or lecturers. Thus, accommodating Social Media Sites (SMSs) in teaching practices is essential for professional educators in Indonesia.

  10. Public Values

    DEFF Research Database (Denmark)

    Beck Jørgensen, Torben; Rutgers, Mark R.

    2015-01-01

    administration is approached in terms of processes guided or restricted by public values and as public value creating: public management and public policy-making are both concerned with establishing, following and realizing public values. To study public values a broad perspective is needed. The article suggest......This article provides the introduction to a symposium on contemporary public values research. It is argued that the contribution to this symposium represent a Public Values Perspective, distinct from other specific lines of research that also use public value as a core concept. Public...... a research agenda for this encompasing kind of public values research. Finally the contributions to the symposium are introduced....

  11. Automated simultaneous measurement of the δ(13) C and δ(2) H values of methane and the δ(13) C and δ(18) O values of carbon dioxide in flask air samples using a new multi cryo-trap/gas chromatography/isotope ratio mass spectrometry system.

    Science.gov (United States)

    Brand, Willi A; Rothe, Michael; Sperlich, Peter; Strube, Martin; Wendeberg, Magnus

    2016-07-15

    The isotopic composition of greenhouse gases helps to constrain global budgets and to study sink and source processes. We present a new system for high-precision stable isotope measurements of carbon, hydrogen and oxygen in atmospheric methane and carbon dioxide. The design is intended for analyzing flask air samples from existing sampling programs without the need for extra sample air for methane analysis. CO2 and CH4 isotopes are measured simultaneously using two isotope ratio mass spectrometers, one for the analysis of δ(13) C and δ(18) O values and the second one for δ(2) H values. The inlet carousel delivers air from 16 sample positions (glass flasks 1-5 L and high-pressure cylinders). Three 10-port valves take aliquots from the sample stream. CH4 from 100-mL air aliquots is preconcentrated in 0.8-mL sample loops using a new cryo-trap system. A precisely calibrated working reference air is used in parallel with the sample according to the Principle of Identical Treatment. It takes about 36 hours for a fully calibrated analysis of a complete carousel including extractions of four working reference and one quality control reference air. Long-term precision values, as obtained from the quality control reference gas since 2012, account for 0.04 ‰ (δ(13) C values of CO2 ), 0.07 ‰ (δ(18) O values of CO2 ), 0.11 ‰ (δ(13) C values of CH4 ) and 1.0 ‰ (δ(2) H values of CH4 ). Within a single day, the system exhibits a typical methane δ(13) C standard deviation (1σ) of 0.06 ‰ for 10 repeated measurements. The system has been in routine operation at the MPI-BGC since 2012. Consistency of the data and compatibility with results from other laboratories at a high precision level are of utmost importance. A high sample throughput and reliability of operation are important achievements of the presented system to cope with the large number of air samples to be analyzed. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  12. 实时剪切波弹性成像定量及定性评价乳腺良恶性实性病变%Diagnostic Value of Quantitative and Qualitative Shear Wave Elastography for Solid Breast Masses

    Institute of Scientific and Technical Information of China (English)

    李奥; 彭晓静; 袁涛; 薛海燕; 林红军; 叶新华

    2016-01-01

    Objective To assess the diagnostic value of quantitative and qualitative shear wave elastography (SWE) in the evaluation of solid breast masses and to determine the most discriminatory parameter.Methods A total of 166 breast masses (malignant 46,benign 120) in 155 women who underwent SWE before ultrasound-guided core biopsy or surgery were analysed.The quantitative SWE parameters including maximum elasticity (Emax),mean elasticity (Emea),standard deviation of the elasticity (Esd) and the lesion-to-fat elasticity ratio (Eratio) were measured.The qualitative SWE features were assessed using a four-colour overlay pattern.Results The differences of Emax,Emea,Esd and Eratio within benign and malignant lesions were statistically significant (P<0.0001).The AUC of Emax (0.920) was the highest among elasticity values with the optimal cutoff value of 49.27 kPa and the AUC of SWE colour pattern was 0.873 with the cutoff of pattern Ⅲ.When Emax and colour pattern were combined,the sensitivity,specificity and accuracy were 89.1%,91.7 %,91.0 % respectively.Conclusions Conclusions Both quantitative and qualitative SWE could provide further diagnostic information during ultrasound characterization of solid breast masses.Emax (cutoff,49.27 kPa) appeared to be the most discriminatory parameter.%目的 分析实时剪切波弹性成像技术(SWE)各定量参数及弹性图像特征在鉴别乳腺良恶性实性病变中的价值,筛选出最佳的诊断参数.方法 对155例女性患者共166个乳腺病变行常规超声及SWE检查,定量测量病灶弹性模量值,包括最大弹性值Emax、平均弹性值Emea、弹性标准差Esd及病灶/脂肪弹性比Eratio;定性评估病灶弹性图像特征,并将其分为四种类型.结果 SWE弹性图像类型及定量参数Emax、Emea、Esd及Eratio在乳腺良恶性病灶间均有显著性统计学差异(P<0.0001).通过绘制ROC曲线,Emax的AUC在所有定量参数中最大(0.920),界值为49.27 kPa

  13. Mass spectrometry in clinical chemistry

    International Nuclear Information System (INIS)

    Pettersen, J.E.

    1977-01-01

    A brief description is given of the functional elements of a mass spectrometer and of some currently employed mass spectrometric techniques, such as combined gas chromatography-mass spectrometry, mass chromatography, and selected ion monitoring. Various areas of application of mass spectrometry in clinical chemistry are discussed, such as inborn errors of metabolism and other metabolic disorders, intoxications, quantitative determinations of drugs, hormones, gases, and trace elements, and the use of isotope dilution mass spectrometry as a definitive method for the establishment of true values for concentrations of various compounds in reference sera. It is concluded that mass spectrometry is of great value in clinical chemistry. (Auth.)

  14. The prognostic value of monosomal karyotype (MK) in higher-risk patients with myelodysplastic syndromes treated with 5-Azacitidine. A retrospective analysis of the Hellenic (Greek) MDS Study Group.

    Science.gov (United States)

    Papageorgiou, Sotirios G; Vasilatou, Diamantina; Kontos, Christos K; Kotsianidis, Ioannis; Symeonidis, Argiris; Galanopoulos, Athanasios G; Hatzimichael, Eleftheria; Megalakaki, Aekaterini; Poulakidas, Elias; Diamantopoulos, Panagiotis; Vassilakopoulos, Theodoros; Zikos, Panagiotis; Papadaki, Helen; Mparmparousi, Despoina; Bouronikou, Eleni; Panayiotidis, Panayiotis; Viniou, Nora-Athina; Pappa, Vassiliki

    2018-04-16

    In this study, we investigated the incidence and prognostic impact of monosomal karyotype (MK) in 405 higher-risk MDS patients treated with 5-AZA. The MK was present in 66 out of 405 (16.3%) patients, most of whom had complex karyotype (CK). MK was strongly associated with CK and the cytogenetic risk defined according to IPSS-R, as well as with high-risk disease, according to IPSS (P=0.029), IPSS-R (PMDS treated with 5-AZA. Furthermore, we showed that in MDS with high or very-high IPSS-R risk score, MK can further distinguish patients with worse outcome. This article is protected by copyright. All rights reserved. © 2018 Wiley Periodicals, Inc.

  15. Static-light meson masses from twisted mass lattice QCD

    International Nuclear Information System (INIS)

    Jansen, Karl; Michael, Chris; Shindler, Andrea; Wagner, Marc

    2008-08-01

    We compute the static-light meson spectrum using two-flavor Wilson twisted mass lattice QCD. We have considered five different values for the light quark mass corresponding to 300 MeV PS S mesons. (orig.)

  16. Values Research

    Science.gov (United States)

    2009-10-01

    that individualistic employees in individualistic organizations and collectivistic employees in collectivistic organizations show greater job...with Parsons’ causal assumption, in the nineties values were recognized on top of the cultural control –values control norms which in turn control...determines intention which may end in behavior. 7 Defining Human Values Cross- cultural theories on values emerged in the 80s developed by three main

  17. Differentiation of mass-forming focal pancreatitis from pancreatic ductal adenocarcinoma: value of characterizing dynamic enhancement patterns on contrast-enhanced MR images by adding signal intensity color mapping

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Mimi [Hanyang University College of Medicine, Department of Radiology, Hanyang Medical Center, Seoul (Korea, Republic of); Jang, Kyung Mi [Sungkyunkwan University School of Medicine, Department of Radiology, Samsung Medical Center, Seoul (Korea, Republic of); Sungkyunkwan University School of Medicine, Department of Radiology and Center for Imaging Science, Samsung Medical Center, Seoul (Korea, Republic of); Kim, Jae-Hun; Jeong, Woo Kyoung; Kim, Seong Hyun; Kang, Tae Wook; Kim, Young Kon; Cha, Dong Ik [Sungkyunkwan University School of Medicine, Department of Radiology, Samsung Medical Center, Seoul (Korea, Republic of); Kim, Kyunga [Samsung Medical Center, Biostatics and Clinical Epidemiology Center, Research Institute for Future Medicine, Seoul (Korea, Republic of)

    2017-04-15

    To evaluate the value of dynamic enhancement patterns on contrast-enhanced MR images by adding signal intensity colour mapping (SICM) to differentiate mass-forming focal pancreatitis (MFFP) from pancreatic ductal adenocarcinoma (PDAC). Forty-one clinicopathologically proven MFFPs and 144 surgically confirmed PDACs were enrolled. Laboratory and MR imaging parameters were used to differentiate MFFP from PDAC. In particular, enhancement patterns on MR images adding SICM were evaluated. By using classification tree analysis (CTA), we determined the predictors for the differentiation of MFFP from PDAC. In the CTA, with all parameters except enhancement pattern on SICM images, ductal obstruction grade and T1 hypointensity grade of the pancreatic lesion were the first and second splitting predictor for differentiation of MFFP from PDAC, in order. By adding an enhancement pattern on the SICM images to CTA, the enhancement pattern was the only splitting predictor to differentiate MFFP from PDAC. The CTA model including enhancement pattern on SICM images has sensitivity of 78.0 %, specificity of 99.3 %, and accuracy of 94.6 % for differentiating MFFP from PDAC. The characterization of enhancement pattern for pancreatic lesions on contrast-enhanced MR images adding SICM would be helpful to differentiate MFFP from PDAC. (orig.)

  18. Percentage of free prostate-specific antigen (PSA) is a useful method in deciding to perform prostate biopsy with higher core numbers in patients with low PSA cut-off values.

    Science.gov (United States)

    Yilmaz, Hasan; Ciftci, Seyfettin; Yavuz, Ufuk; Ustuner, Murat; Saribacak, Ali; Dillioglugil, Ozdal

    2015-06-01

    The aim of this study was to evaluate the predictive role of percentage of free prostate-specific antigen (%fPSA) cut-points in prostate cancer (PCa) detection in patients with total PSA (tPSA) levels between 2.5 ng/mL and 10.0 ng/mL. In total, 1321 consecutive initial transrectal ultrasound (TRUS)-guided 12-core biopsies performed between 2005 and 2011 were evaluated retrospectively. Benign pathologies, high-grade prostatic intraepithelial neoplasia, and atypical small acinary proliferations were categorized as noncancerous (benign), and prostate adenocarcinomas were categorized as cancerous (malignant). The patients were categorized according to: Catalona's published %fPSA categories ( 25%); digital rectal examination (DRE) results [benign (negative) or suspicious of malignancy (positive)]. There was a significant relationship between the %fPSA cut-points and detection of PCa in DRE-negative patients. The presence of a 10% cut-point increased the probability of PCa threefold. The %fPSA was significantly more related to PCa than the tPSA value in receiver operating characteristic (ROC) curve analyses (p = 0.001). Based on our findings, a lower %fPSA, especially <10%, is an important parameter when deciding whether to perform a biopsy on patients with a tPSA between 2.5 ng/mL and 10 ng/mL. Copyright © 2015. Published by Elsevier Taiwan.

  19. Methods for recalibration of mass spectrometry data

    Science.gov (United States)

    Tolmachev, Aleksey V [Richland, WA; Smith, Richard D [Richland, WA

    2009-03-03

    Disclosed are methods for recalibrating mass spectrometry data that provide improvement in both mass accuracy and precision by adjusting for experimental variance in parameters that have a substantial impact on mass measurement accuracy. Optimal coefficients are determined using correlated pairs of mass values compiled by matching sets of measured and putative mass values that minimize overall effective mass error and mass error spread. Coefficients are subsequently used to correct mass values for peaks detected in the measured dataset, providing recalibration thereof. Sub-ppm mass measurement accuracy has been demonstrated on a complex fungal proteome after recalibration, providing improved confidence for peptide identifications.

  20. Measurement of Q{sub {beta}} values of neutron-rich Tc to Pd isotopes in the mass range A=110 to A=117; Messung von Q{sub {beta}}-Werten neutronenreicher Tc- bis Pd-Isotope im Massenbereich A=110 bis A=117

    Energy Technology Data Exchange (ETDEWEB)

    Kloeckl, Ingo

    2008-06-15

    The present work describes the measuring of Q{sub {beta}} values of {beta}-instable isotopes of Tc, Ru, Rh and Pd. The mass range A=110 to 117 comprises neutron-rich, short-living isotopes. Due to their small (fission) abundances, few data are known, especially regarding level schemes or gamma radiation. The proton-induced fission and a fast online mass separation was used to produce these nuclides in the IGISOL facility located in Jyvaeskylaein Finland. The {beta},{gamma},X coincidence apparatus used during the experiments allows measuring Q{sub {beta}} values as well as {gamma},X coincidences. The latter represent the basic input data for a calculation of Q{sub {beta}} values out of {beta},{gamma} coincidences. It is so possible to examine nuclides with incomplete level schemes; similarly, these level schemes can be extended using beta,gamma coincidence data. Twelve Q{sub {beta}} values of neutron-rich Tc to Pd isotopes could be determined, yielding nuclear masses, mass defects and neutron separation energies. Eight of them were determined for the first time; another one could be confirmed. For three more, the error of earlier values could be decreased by a factor of nearly ten. The resulting data are of interest for the review of nuclear mass models, they represent also input in astrophysical network calculations. (orig.)

  1. Higher Education and European Regionalism.

    Science.gov (United States)

    Paterson, Lindsay

    2001-01-01

    Speculates about the relationship between two fundamental social changes occurring in Europe: the development of a mass higher education system and the slow decay of the old states that were inherited from the 19th century, eroded from below by various movements for national and regional autonomy, and eroded from above by the growing power and…

  2. Default values

    International Nuclear Information System (INIS)

    1987-08-01

    In making calculations for the purposes of radiation protection, numerical values for parameters used in the calculations are selected. In some cases, data directly applicable to the set of conditions for which the calculations are to be made are unavailable. Therefore, the selection of the values for these parameters may be based on more general data available from the literature or other sources. These values may be referred to as 'default values', that is, values used in default of those based on directly applicable data. The following policy will be applied by Atomic Energy Control Board (AECB) staff in reviewing the radiation protection aspects of submissions associated with licensing, in participating with other organizations in the development of codes and standards, and in any other work which relies to some extent on using default values

  3. Deep Value

    DEFF Research Database (Denmark)

    Asness, Clifford S.; Liew, John M.; Pedersen, Lasse Heje

    premium. Following these episodes, the value strategy has (1) high average returns; (2) low market betas, but high betas to a global value factor; (3) deteriorating fundamentals; (4) negative news sentiment; (5) selling pressure; (6) increased limits to arbitrage; and (7) increased arbitrage activity...

  4. Forestland values.

    Science.gov (United States)

    John H. Beuter; Ralph J. Alig

    2004-01-01

    This issue of the journal of Forestry is devoted to articles about forestland values. Viewed broadly, natural resources and humans are our two basic resources. An expression of the importance of land as a foundation for forest ecosystems is forestland value. Our attitudes about land and the forest ecosystems that they support have changed considerably in recent years....

  5. The Value of Value Sets

    DEFF Research Database (Denmark)

    Sløk-Madsen, Stefan Kirkegaard; Christensen, Jesper

    The world over classrooms in business schools are being taught that corporate values can impact performance. The argument is typically that culture matter more than strategy plans and culture can be influenced and indeed changed by a shared corporate value set. While the claim seems intuitively a...... a unique contribution to the effects of investment in shared company values, and to whether agent rationality can be fundamentally changed by committed organizational efforts....

  6. Value Representations

    DEFF Research Database (Denmark)

    Rasmussen, Majken Kirkegaard; Petersen, Marianne Graves

    2011-01-01

    Stereotypic presumptions about gender affect the design process, both in relation to how users are understood and how products are designed. As a way to decrease the influence of stereotypic presumptions in design process, we propose not to disregard the aspect of gender in the design process......, as the perspective brings valuable insights on different approaches to technology, but instead to view gender through a value lens. Contributing to this perspective, we have developed Value Representations as a design-oriented instrument for staging a reflective dialogue with users. Value Representations...

  7. Unravelling Value

    DEFF Research Database (Denmark)

    Walsh, Matthew

    Paper presented in the symposium “What’s It All Worth? Material Possessions and Value in Past Societies” at 22nd Annual Meeting of the European Association of Archaeologists, Vilnius, Lithuania.......Paper presented in the symposium “What’s It All Worth? Material Possessions and Value in Past Societies” at 22nd Annual Meeting of the European Association of Archaeologists, Vilnius, Lithuania....

  8. Marketing Higher Education: The Survival Value of Integrity

    Science.gov (United States)

    Silber, John R.

    2012-01-01

    Academics are all used to the idea that they have special ethical obligations. They may also, as administrators, recognize special administrative ethical obligations. But they do not like to think of themselves as businessmen, concerned with selling, and few of them indeed have thought directly and hard about the ethical constraints on marketing…

  9. Organisational Values in Higher Education: Perceptions and Preferences of Staff

    Science.gov (United States)

    Kleijnen, Jan; Dolmans, Diana; Muijtjens, Arno; Willems, Jos; Van Hout, Hans

    2009-01-01

    In this paper, staff members' perceptions about the organisational culture are measured. The questions addressed are: what are their opinions about the current and preferred organisational culture? Are there differences between the current and preferred situation? Do the perceptions differ per department? The Organisational Culture Assessment…

  10. Mulheres com síndrome dos ovários policísticos apresentam maior frequência de síndrome metabólica independentemente do índice de massa corpóreo Women with polycystric ovary syndrome have a higher frequency of metabolic syndrome regardless of body mass index

    Directory of Open Access Journals (Sweden)

    Anderson Sanches Melo

    2012-01-01

    Full Text Available OBJETIVO: Avaliar a prevalência de síndrome metabólica e dos seus critérios definidores em mulheres com síndrome dos ovários policísticos do Sudeste brasileiro, estratificadas de acordo com o índice de massa corpóreo e comparadas com controles ovulatórias. MÉTODOS: Estudo transversal, realizado com 332 mulheres em idade reprodutiva, que foram divididas em dois grupo: Controle, constituído por 186 mulheres com ciclos menstruais regulares, sintomas ovulatórios e sem diagnóstico de síndrome dos ovários policísticos ou outra anovulação crônica; e Síndrome dos ovários policísticos, composto por 146 mulheres com o diagnóstico de síndrome dos ovários policísticos - Consenso de Rotterdam ASRM/ESHRE. Cada um destes grupos foi estratificado de acordo com o índice de massa corpóreo (PURPOSE: To assess the prevalence of metabolic syndrome and of its defining criteria in women with polycystic ovary syndrome from the Brazilian Southeast, who were stratified according to body mass index and compared to ovulatory controls. METHODS: This was a cross-sectional study conducted on 332 women of reproductive age, who were divided into two groups: Control, consisting of 186 women with regular menstrual cycles and ovulatory symptoms and without a diagnosis of polycystic ovary syndrome or other type of chronic anovulation, and the Polycystic ovary syndrome,Group, consisting of 146 women with a diagnosis of polycystic ovary syndrome (Rotterdam Consensus ASRM/ESHRE. Each group was stratified according to the body mass index, as follows: body mass index ( < 25 ≥25 and <30, and ≥ 30 kg/m². The frequencies of metabolic syndrome and of its defining criteria and the clinical and hormonal characteristics (follicle stimulating hormone, total testosterone, dehydroepiandrostenedione sulfate were analyzed. RESULTS: The frequency of metabolic syndrome was six times higher in the obese Polycystic ovary syndrome Group than among control women with the

  11. Negative mass

    International Nuclear Information System (INIS)

    Hammond, Richard T

    2015-01-01

    Some physical aspects of negative mass are examined. Several unusual properties, such as the ability of negative mass to penetrate any armor, are analysed. Other surprising effects include the bizarre system of negative mass chasing positive mass, naked singularities and the violation of cosmic censorship, wormholes, and quantum mechanical results as well. In addition, a brief look into the implications for strings is given. (paper)

  12. Nominal Mass?

    Science.gov (United States)

    Attygalle, Athula B; Pavlov, Julius

    2017-08-01

    The current IUPAC-recommended definition of the term "nominal mass," based on the most abundant naturally occurring stable isotope of an element, is flawed. We propose that Nominal mass should be defined as the sum of integer masses of protons and neutrons in any chemical species. In this way, all isotopes and isotopologues can be assigned a definitive identifier. Graphical Abstract ᅟ.

  13. Public Value: rethinking value creation

    OpenAIRE

    Meynhardt, Timo; Gomez, Peter; Strathoff, Pepe; Hermann, Carolin

    2014-01-01

    Managers might refute public criticism of their business as an attitude of taking everything for granted in a saturated society, but ignoring Public Value aspects can threaten the success of new products and even the survival of entire firms.

  14. Measurement of mass and isotopic fission yields for heavy fission products with the LOHENGRIN mass spectrometer

    International Nuclear Information System (INIS)

    Bail, A.

    2009-05-01

    In spite of the huge amount of fission yield data available in different libraries, more accurate values are still needed for nuclear energy applications and to improve our understanding of the fission process. Thus measurements of fission yields were performed at the mass spectrometer Lohengrin at the Institut Laue-Langevin in Grenoble, France. The mass separator Lohengrin is situated at the research reactor of the institute and permits the placement of an actinide layer in a high thermal neutron flux. It separates fragments according to their atomic mass, kinetic energy and ionic charge state by the action of magnetic and electric fields. Coupled to a high resolution ionization chamber the experiment was used to investigate the mass and isotopic yields of the light mass region. Almost all fission yields of isotopes from Th to Cf have been measured at Lohengrin with this method. To complete and improve the nuclear data libraries, these measurements have been extended in this work to the heavy mass region for the reactions 235 U(n th ,f), 239 Pu(n th ,f) and 241 Pu(n th ,f). For these higher masses an isotopic separation is no longer possible. So, a new method was undertaken with the reaction 239 Pu(n th ,f) to determine the isotopic yields by spectrometry. These experiments have allowed to reduce considerably the uncertainties. Moreover the ionic charge state and kinetic energy distributions were specifically studied and have shown, among others, nanosecond isomers for some masses. (author)

  15. Comparison of fat-free mass index and fat mass index in Chinese adults.

    Science.gov (United States)

    Lu, Y; Shu, H; Zheng, Y; Li, C; Liu, M; Chen, Z; He, X

    2012-09-01

    To compare the characteristics of body composition for different gender and age in a large number of apparently healthy Chinese subjects, and to determine reference values for fat-free mass index (FFMI) and fat mass index (FMI). In total, 61,382 Chinese adults (age range: 18-92 years) were consecutively enrolled into the study. Body composition was measured using bioelectrical impedance analysis with a tetrapolar impedance meter. The skeletal muscle mass, fat-free mass (FFM), FFMI and body mass index (BMI) were significantly higher in men than in women (Pnormal BMI (BMI 18.5-23.9 kg/m(2), 18-92 years), the reference values (5th-95th percentile) of FM%, FFMI and FMI were 9.7-34.5%, 14.15-19.76 and 1.99-7.75 kg/m(2) in men, and 18.1-35.8%, 13.82-17.89 and 3.68-8.16 kg/m(2) in women, respectively. Reference intervals for FFMI and FMI could be of practical value for the clinical evaluation of a deficit in FFM with or without excess FM for a given age category, complementing the classical concept of BMI in a more qualitative manner, although these indices are only suggestive indications for the degree of obesity. In contrast to BMI, similar reference ranges of FFMI seem to be more utilizable with advancing age.

  16. Mass of the photon

    International Nuclear Information System (INIS)

    Goldhaber, A.S.; Nieto, M.M.

    1976-01-01

    Several experiments are discussed for which results are equivalent to the catching and weighing of a photon. It is noted that none of the experiments has proved the rest mass to be zero and that such a proof may be impossible. It is shown by such experiments that the rest mass is less than the limit of accuracy of the experiment. These limits have approached ever closer to zero, and the most recent values are exceedingly small

  17. Predictive values of Bi-Rads categories 3, 4 and 5 in non-palpable breast masses evaluated by mammography, ultrasound and magnetic resonance imaging; Valores preditivos das categorias 3, 4 e 5 do sistema Bi-Rads em lesoes mamarias nodulares nao-palpaveis avaliadas por mamografia, ultra-sonografia e ressonancia magnetica

    Energy Technology Data Exchange (ETDEWEB)

    Roveda Junior, Decio; Fleury, Eduardo de Castro Faria [Santa Casa de Misericordia de Sao Paulo, SP (Brazil). Faculdade de Ciencias Medicas. Servico de Diagnostico por Imagem]. E-mail: decio.jr@uol.com.br; Piato, Sebastiao [Santa Casa de Misericordia de Sao Paulo, SP (Brazil). Dept. de Obstetricia e Ginecologia. Clinica Ginecologica; Oliveira, Vilmar Marques de [Santa Casa de Misericordia de Sao Paulo, SP (Brazil). Dept. de Obstetricia e Ginecologia. Ginecologia Geral; Rinaldi, Jose Francisco [Santa Casa de Misericordia de Sao Paulo, SP (Brazil). Dept. de Obstetricia e Ginecologia. Clinica de Mastologia; Ferreira, Carlos Alberto Pecci [Santa Casa de Misericordia de Sao Paulo, SP (Brazil). Faculdade de Ciencias Medicas. Dept. de Clinica Medica. Servico de Imagenologia Mamaria

    2007-03-15

    Objective: To evaluate the predictive value of BI-RADS{sup TM} categories 3, 4 and 5 in non-palpable breast masses assessed by mammography, ultrasound and magnetic resonance imaging. Materials And Methods: Twenty-nine patients with BI-RADS categories 3, 4 and 5 non-palpable breast masses identified by mammograms were submitted to complementary ultrasound and magnetic resonance imaging studies, besides excisional biopsy. In total, 30 biopsies were performed. The lesions as well as their respective BI-RADS classification into 3, 4 and 5 were correlated with the histopathological results. The predictive values calculation was made by means of specific mathematical equations. Results: Negative predictive values for category 3 were: mammography, 69.23%; ultrasound, 70.58%; and magnetic resonance imaging, 100%. Positive predictive values for category 4 were: mammography, 63.63%; ultrasound, 50%; and magnetic resonance imaging, 30.76%. For category 5, positive predictive values were: mammography and ultrasound, 100%; and magnetic resonance imaging, 92.85%. Conclusion: For category 3, the negative predictive value of magnetic resonance imaging was high, and for categories 4 and 5, the positive predictive values of the three modalities were moderate. (author)

  18. Add Value

    DEFF Research Database (Denmark)

    Kobbelgaard, Cecilie Elisabeth

    2016-01-01

    "Add Value – kend din kunde" er et brætspil, som giver både offentlige og private virksomheder unikke muligheder for at forbedre deres service overfor kunderne. Spillet giver, på en alternativ og handlingsorienteret måde, mulighed for at blive skarpere på kundeoplevelsen – hvor er der værdi...... at hente, og hvor kan der spares på tid og ressourcer? Dette samtidig med, at kunderne får den oplevelse og service, de forventer. Når I spiller "Add Value – kend din kunde" sættes der fokus på Jeres kundeservice ud fra kundens perspektiv, og det er i alle Jeres kontaktflader med kunden. Lige fra kunden...

  19. Top Quark Mass

    CERN Document Server

    Mulders, Martijn

    2016-01-01

    Ever since the discovery of the top quark at the Tevatron collider in 1995 the measurement of its mass has been a high priority. As one of the fundamental parameters of the Standard Theory of particle physics, the precise value of the top quark mass together with other inputs provides a test for the self-consistency of the theory, and has consequences for the stability of the Higgs field that permeates the Universe. In this review I will briefly summarize the experimental techniques used at the Tevatron and the LHC experiments throughout the years to measure the top quark mass with ever improving accuracy, and highlight the recent progress in combining all measurements in a single world average combination. As experimental measurements became more precise, the question of their theoretical interpretation has become important. The difficulty of relating the measured quantity to the fundamental top mass parameter has inspired alternative measurement methods that extract the top mass in complementary ways. I wil...

  20. Conservation Value

    OpenAIRE

    Tisdell, Clement A.

    2010-01-01

    This paper outlines the significance of the concept of conservation value and discusses ways in which it is determined paying attention to views stemming from utilitarian ethics and from deontological ethics. The importance of user costs in relation to economic decisions about the conservation and use of natural resources is emphasised. Particular attention is given to competing views about the importance of conserving natural resources in order to achieve economic sustainability. This then l...

  1. Minimum critical mass systems

    International Nuclear Information System (INIS)

    Dam, H. van; Leege, P.F.A. de

    1987-01-01

    An analysis is presented of thermal systems with minimum critical mass, based on the use of materials with optimum neutron moderating and reflecting properties. The optimum fissile material distributions in the systems are obtained by calculations with standard computer codes, extended with a routine for flat fuel importance search. It is shown that in the minimum critical mass configuration a considerable part of the fuel is positioned in the reflector region. For 239 Pu a minimum critical mass of 87 g is found, which is the lowest value reported hitherto. (author)

  2. Comparisons of predictive values of sarcopenia with different muscle mass indices in Korean rural older adults: a longitudinal analysis of the Aging Study of PyeongChang Rural Area

    Directory of Open Access Journals (Sweden)

    Jang IY

    2018-01-01

    Full Text Available Il-Young Jang,1,2,* Hee-Won Jung,3,4,* Chang Ki Lee,5 Sang Soo Yu,2 Young Soo Lee,1 Eunju Lee1 1Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, 2PyeongChang Health Center & County Hospital, Gangwon-Do, 3Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST, Daejeon, 4Geriatric Center, Seoul National University Bundang Hospital, Gyeonggi-Do, 5Goldman Urology Clinic, Seoul, Republic of Korea *These authors contributed equally to this work Purpose: It is important to define lean muscle mass when diagnosing sarcopenia, but there is still controversy on the clinical implication of sarcopenia derived by height, weight, and body mass index (BMI adjusted muscle mass indices. We aimed to evaluate the longitudinal clinical relevance of 3 sarcopenia definitions in the Korean population. Patients and methods: We conducted comprehensive geriatric assessments for 1,379 community-dwelling older participants in the Aging Study of PyeongChang Rural Area (ASPRA cohort and followed them up prospectively for death, institutionalization, and disability every 3 months. Sarcopenia was defined using the Asian Working Group consensus algorithm, combining grip strength, gait speed, and muscle mass.Results: Among 1,343 participants (mean age: 76 years, 741 women analyzed, there were 29 deaths and 89 institutionalizations during 22.0 ± 8.3 months follow-up (mean ± SD. All three muscle indices correlated to age and sex. All sarcopenia criteria with muscle mass indices of height, weight, and body mass index (BMI adjustment significantly predicted death or institutionalization. However, when adjusted for age and sex, only the sarcopenia criteria with muscle mass index of height adjustment were significantly associated with major adverse health outcomes.Conclusion: Adjusting age and gender, the sarcopenia definition from the quintile-based muscle index of height

  3. NEUTRINO MASS

    OpenAIRE

    Kayser, Boris

    1988-01-01

    This is a review article about the most recent developments on the field of neutrino mass. The first part of the review introduces the idea of neutrino masses and mixing angles, summarizes the most recent experimental data then discusses the experimental prospects and challenges in this area. The second part of the review discusses the implications of these results for particle physics and cosmology, including the origin of neutrino mass, the see-saw mechanism and sequential dominance, and la...

  4. Neutrino mass

    International Nuclear Information System (INIS)

    Robertson, R.G.H.

    1992-01-01

    Despite intensive experimental work since the neutrino's existence was proposed by Pauli 60 years ago, and its first observation by Reines and Cowan almost 40 years ago, the neutrino's fundamental properties remain elusive. Among those properties are the masses of the three known flavors, properties under charge conjugation, parity and time-reversal, and static and dynamic electromagnetic moments. Mass is perhaps the most fundamental, as it constrains the other properties. The present status of the search for neutrino mass is briefly reviewed

  5. [Effect of anticancer treatment on leptin level, fat body mass (FM) and lean body mass (LBM)].

    Science.gov (United States)

    Krawczyk-Rybak, Maryna; Muszyńska-Rosłan, Katarzyna; Konstantynowicz, Jerzy; Solarz, Elzbieta; Wołczynski, Sławomir; Protas, Piotr

    2004-01-01

    Leptin plays an important role in the metabolism of adipose tissue. Considering that malignancy and its treatment cans affect normal development in childhood. We analysed the correlations between serum leptin levels and body composition after anticancer treatment. We studied 33 survivors (24 boys and 9 girls) who before our study, have been treated for acute lymphoblastic leukaemia (ALL) (n=23) and Hodgkin disease (n=10) after 7.15+/-3.5 years. Sixteen patients with ALL received cranial irradiation (12Gy). We measured body mass index (BM1) fat mass (FM) and lean body mass (LBM) using dual energy x-ray absorptiometry (DXA). We compared these results to the results obtained from reference values (SD score). Leptin levels were measured with the RIA method. 1. Mean leptin levels were higher in girls after puberty (10.93 ng/mL+/-8.9) than in boys (3.73 ng/mL+/-3. 7). In boys no differences were found in leptin levels between T2-4 and T5 stages. In girls the leptin values increased after puberty. Leptin SD score levels were higher in boys during (1.55 +/-1.0) and after puberty (1.46+/-0.75) and in girls - after puberty (1.19 +/-1.51). We did not find any influence of cranial irradiation (12Gy) or various methotrexate doses (5 g/m(2) vs. 19/m(2)) leptin values. 2. No difference in BMI SD score was found within the whole study group. 3. FM did not change ill boys during and after puberty, although FM SD score were higher during puberty (2.98 +/-4.8). In girls FM and FM SD score were higher after puberty. In boys and girls LBM augmented with pubertal development but LBM SD score in boys were lower after puberty (-1.67 +/-1.7) in comparison to puberty (0.2 +/-1.7). No differences were found between LBM SD score in girls during and after puberty. 4. We found a correlation between leptin levels and BMI (r=0.59 p=0.001) and FM (r=0.77 p=0.0001). 5. Relation of FM to LBM in boys remained unchanged, however in girls it increased within pubertal development. l. Anticancer

  6. 高职院校应届毕业生职业价值观研究--基于日照市高职院校调查数据的分析%Research on Professional Values of Fresh Graduates from Higher Vocational Colleges of Rizhao City

    Institute of Scientific and Technical Information of China (English)

    苗薇薇; 张兰兰; 张立新

    2015-01-01

    调查研究结果发现,高职院校应届毕业生的职业价值观整体上是健康向上的,但仍存在很大的完善空间;高职院校应届毕业生更多地把职业价值及其目的归结为人际关系、成就感和独立性三个方面,但在追求新意、美感和安全感方面的意识或预期较低;不同群体高职新生间的职业价值观存在一定的差异。可以通过加强就业教育、实践教育和人文教育等措施,帮助高职院校大学生树立和完善正确的职业价值观。%Professional values of the fresh graduates from higher vocational colleges are generally healthy,but there is still a lot of room for improvement. The fresh graduates understand professional values from three aspects-interper-sonal relationships, sense of achievement and independence, but their awareness or expectations are relatively low in pursuit of novelty, beauty and safety. Professional values vary among different groups of higher vocational students. It can help students establish and improve the profesional values by strengthening employment education, practical edu-cation and humanistic education.

  7. Mass Society

    DEFF Research Database (Denmark)

    Borch, Christian

    2017-01-01

    the negative features usually ascribed by late nineteenth-century crowd psychology to spontaneous crowds, and attributes these to the entire social fabric. However, in contrast to crowd psychology, theorists of mass society often place greater emphasis on how capitalism, technological advances, or demographic......Mass society is a societal diagnosis that emphasizes – usually in a pejorative, modernity critical manner – a series of traits allegedly associated with modern society, such as the leveling of individuality, moral decay, alienation, and isolation. As such, the notion of mass society generalizes...... developments condition such negative features, and some theorists argue that mass society produces a propensity to totalitarianism. Discussions of mass society culminated in the early and mid-twentieth century....

  8. Valuing hope.

    Science.gov (United States)

    McMillan, John; Walker, Simon; Hope, Tony

    2014-01-01

    This article argues that hope is of value in clinical ethics and that it can be important for clinicians to be sensitive to both the risks of false hope and the importance of retaining hope. However, this sensitivity requires an understanding of the complexity of hope and how it bears on different aspects of a well-functioning doctor-patient relationship. We discuss hopefulness and distinguish it, from three different kinds of hope, or 'hopes for', and then relate these distinctions back to differing accounts of autonomy. This analysis matters because it shows how an overly narrow view of the ethical obligations of a clinician to their patient, and autonomy, might lead to scenarios where patients regret the choices they make.

  9. Efficient mass calibration of magnetic sector mass spectrometers

    International Nuclear Information System (INIS)

    Roddick, J.C.

    1996-01-01

    Magnetic sector mass spectrometers used for automatic acquisition of precise isotopic data are usually controlled with Hall probes and software that uses polynomial equations to define and calibrate the mass-field relations required for mass focusing. This procedure requires a number of reference masses and careful tuning to define and maintain an accurate mass calibration. A simplified equation is presented and applied to several different magnetically controlled mass spectrometers. The equation accounts for nonlinearity in typical Hall probe controlled mass-field relations, reduces calibration to a linear fitting procedure, and is sufficiently accurate to permit calibration over a mass range of 2 to 200 amu with only two defining masses. Procedures developed can quickly correct for normal drift in calibrations and compensate for drift during isotopic analysis over a limited mass range such as a single element. The equation is: Field A·Mass 1/2 + B·(Mass) p where A, B, and p are constants. The power value p has a characteristic value for a Hall probe/controller and is insensitive to changing conditions, thus reducing calibration to a linear regression to determine optimum A and B. (author). 1 ref., 1 tab., 6 figs

  10. Efficient mass calibration of magnetic sector mass spectrometers

    Energy Technology Data Exchange (ETDEWEB)

    Roddick, J C

    1997-12-31

    Magnetic sector mass spectrometers used for automatic acquisition of precise isotopic data are usually controlled with Hall probes and software that uses polynomial equations to define and calibrate the mass-field relations required for mass focusing. This procedure requires a number of reference masses and careful tuning to define and maintain an accurate mass calibration. A simplified equation is presented and applied to several different magnetically controlled mass spectrometers. The equation accounts for nonlinearity in typical Hall probe controlled mass-field relations, reduces calibration to a linear fitting procedure, and is sufficiently accurate to permit calibration over a mass range of 2 to 200 amu with only two defining masses. Procedures developed can quickly correct for normal drift in calibrations and compensate for drift during isotopic analysis over a limited mass range such as a single element. The equation is: Field A{center_dot}Mass{sup 1/2} + B{center_dot}(Mass){sup p} where A, B, and p are constants. The power value p has a characteristic value for a Hall probe/controller and is insensitive to changing conditions, thus reducing calibration to a linear regression to determine optimum A and B. (author). 1 ref., 1 tab., 6 figs.

  11. Pebble-isolation mass: Scaling law and implications for the formation of super-Earths and gas giants

    Science.gov (United States)

    Bitsch, Bertram; Morbidelli, Alessandro; Johansen, Anders; Lega, Elena; Lambrechts, Michiel; Crida, Aurélien

    2018-04-01

    The growth of a planetary core by pebble accretion stops at the so-called pebble isolation mass, when the core generates a pressure bump that traps drifting pebbles outside its orbit. The value of the pebble isolation mass is crucial in determining the final planet mass. If the isolation mass is very low, gas accretion is protracted and the planet remains at a few Earth masses with a mainly solid composition. For higher values of the pebble isolation mass, the planet might be able to accrete gas from the protoplanetary disc and grow into a gas giant. Previous works have determined a scaling of the pebble isolation mass with cube of the disc aspect ratio. Here, we expand on previous measurements and explore the dependency of the pebble isolation mass on all relevant parameters of the protoplanetary disc. We use 3D hydrodynamical simulations to measure the pebble isolation mass and derive a simple scaling law that captures the dependence on the local disc structure and the turbulent viscosity parameter α. We find that small pebbles, coupled to the gas, with Stokes number τf gap at pebble isolation mass. However, as the planetary mass increases, particles must be decreasingly smaller to penetrate the pressure bump. Turbulent diffusion of particles, however, can lead to an increase of the pebble isolation mass by a factor of two, depending on the strength of the background viscosity and on the pebble size. We finally explore the implications of the new scaling law of the pebble isolation mass on the formation of planetary systems by numerically integrating the growth and migration pathways of planets in evolving protoplanetary discs. Compared to models neglecting the dependence of the pebble isolation mass on the α-viscosity, our models including this effect result in higher core masses for giant planets. These higher core masses are more similar to the core masses of the giant planets in the solar system.

  12. Fair Value or Market Value?

    Directory of Open Access Journals (Sweden)

    Bogdan Cosmin Gomoi

    2014-12-01

    Full Text Available When taking into consideration the issue of defining the “fair value” concept, those less experimented in the area often fall in the “price trap”, which is considered as an equivalent of the fair value of financial structures. This valuation basis appears as a consequence of the trial to provide an “accurate image” by the financial statements and, also, as an opportunity for the premises offered by the activity continuing principle. The specialized literature generates ample controversies regarding the “fair value” concept and the “market value” concept. The paper aims to debate this issue, taking into account various opinions.

  13. Mass hysteria

    CERN Document Server

    Hellemans, Alexander

    2004-01-01

    Considerable research is being undertaken to identify the Higgs particle that is believed to give things their mass. According to the standard model, what we call mass is really an indication of how strongly particles interact with an invisible syrupy substance called the Higgs field. Quantum mechanics say that the mass-giving field can also be thought of as a sea of electrically neutral Higgs particles that should be dislodged in collisions between subatomic particles with high enough energies. Particle physicists expect the Higgs to exist only for a fleeting moment before decaying into other particles, which are caught in a detector. (Edited abstract).

  14. Valuing vaccination.

    Science.gov (United States)

    Bärnighausen, Till; Bloom, David E; Cafiero-Fonseca, Elizabeth T; O'Brien, Jennifer Carroll

    2014-08-26

    Vaccination has led to remarkable health gains over the last century. However, large coverage gaps remain, which will require significant financial resources and political will to address. In recent years, a compelling line of inquiry has established the economic benefits of health, at both the individual and aggregate levels. Most existing economic evaluations of particular health interventions fail to account for this new research, leading to potentially sizable undervaluation of those interventions. In line with this new research, we set forth a framework for conceptualizing the full benefits of vaccination, including avoided medical care costs, outcome-related productivity gains, behavior-related productivity gains, community health externalities, community economic externalities, and the value of risk reduction and pure health gains. We also review literature highlighting the magnitude of these sources of benefit for different vaccinations. Finally, we outline the steps that need to be taken to implement a broad-approach economic evaluation and discuss the implications of this work for research, policy, and resource allocation for vaccine development and delivery.

  15. HIGHER EDUCATION IN NIGERIA

    African Journals Online (AJOL)

    Dr Obe

    to sort out all the relevant facts and factors from others which are ... as another attracts attention: a "quality" totally unacceptable ... extremely selective and carefully tailored. ... cultivate a spirit of mass enlightenment an acute of realisation that ...

  16. MR findings of primary scalp mass

    International Nuclear Information System (INIS)

    Kim, Jee Eun; Hwang, Hee Young; Park, Sung Hye; Kim, Young Chae; Lee, Young Suk

    1996-01-01

    To evaluate the diagnostic value of MRI, we compared MR images of primary scalp mass with pathological findings. Eight cases in seven patients who had presented primary scalp mass during the previous three years were evaluated by MRI and confirmed with surgical excision and pathologic evaluation. 0.38T(Resonex 4000, USA) MRI was used and all MR images were analysed retrospectively. Eight pathologically confirmed cases consisted of three cases of epidermal cysts, one of steatocystoma simplex, three of neurofibromatosis and one of lymphangioma. All epidermal cysts were located in the occipital area and showed a higher signal intensity than CSF in T1WI, and proton density and variable signal intensity in T2WI. The Steatocystoma showed a signal iniensity similar to fat in T1WI and proton density and a lower signal intensity than fat in T2WI. Neurofibromatosis accounted for three cases in two neurofibromatosis patients;one was located in the right parieto-occipital area and accompanied by hematoma and skull defect; two cases were located in the occipital and posterior cervical area of the same patient. The masses showed a higher signal intensity than muscle in T1WI and hyper or isointensity in T2WI with well enhancement. The lymphangioma showed a signal intensity similar to CSF in all pulse sequences and contained a fat component. MRI is a useful modality for evaluating primary scalp mass

  17. Monetizing French Distance Education: A Field Enquiry on Higher Education Value(s)

    Science.gov (United States)

    Olivier, Marty

    2014-01-01

    A field enquiry in French distance education allows us to analyze the evolution of a specific institution towards new public management: Parallel to a trend of free courseware and open education, there is a paradoxical reality of distance education monetization. Whereas history shows how traditional French education is a state controlled public…

  18. Unification and fermion mass structure

    International Nuclear Information System (INIS)

    Ross, Graham G.; Serna, Mario

    2008-01-01

    Grand Unified Theories predict relationships between the GUT-scale quark and lepton masses. Using new data in the context of the MSSM, we update the values and uncertainties of the masses and mixing angles for the three generations at the GUT scale. We also update fits to hierarchical patterns in the GUT-scale Yukawa matrices. The new data shows not all the classic GUT-scale mass relationships remain in quantitative agreement at small to moderate tanβ. However, at large tanβ, these discrepancies can be eliminated by finite, tanβ-enhanced, radiative, threshold corrections if the gluino mass has the opposite sign to the wino mass

  19. Reference values for basic human anatomical and physiological characteristics for use in radiation protection

    International Nuclear Information System (INIS)

    Boecker, B.B.

    2003-01-01

    A new publication prepared by the ICRP Task Group on Reference Man. Basic anatomical and physiological data for use in radiological protection: reference values, is focused on those human characteristics that are important for dosimetric calculations. Moving from the past emphasis on a Reference Man. the new report presents a series of reference values for both male and female subjects of six different ages - newborn, 1, 5, 10, 15 y, and adult. In selecting reference values, the task group has used data on Western Europeans and North Americans because these populations have been well studied with respect to anatomy, body composition and physiology. When appropriate, comparisons are made between the chosen reference values and data from several Asian populations. The reference values for height and body mass are higher than those reported for various Asian populations. However, the reported masses of individual organs and tissues, particularly for China and Japan, are similar to the reference values. (author)

  20. Globalisation and Higher Education

    NARCIS (Netherlands)

    Marginson, Simon; van der Wende, Marijk

    2007-01-01

    Economic and cultural globalisation has ushered in a new era in higher education. Higher education was always more internationally open than most sectors because of its immersion in knowledge, which never showed much respect for juridical boundaries. In global knowledge economies, higher education

  1. Open string topological amplitudes and gaugino masses

    International Nuclear Information System (INIS)

    Antoniadis, I.; Narain, K.S.; Taylor, T.R.

    2005-09-01

    We discuss the moduli-dependent couplings of the higher derivative F-terms (TrW 2 ) h-1 , where W is the gauge N =1 chiral superfield. They are determined by the genus zero topological partition function F (0,h) , on a world-sheet with h boundaries. By string duality, these terms are also related to heterotic topological amplitudes studied in the past, with the topological twist applied only in the left-moving supersymmetric sector of the internal N =(2,0) superconformal field theory. The holomorphic anomaly of these couplings relates them to terms of the form Π n (TrW 2 ) h-2 , where Π's represent chiral projections of non-holomorphic functions of chiral superfields. An important property of these couplings is that they violate R-symmetry for h ≥ 3. As a result, once supersymmetry is broken by D-term expectation values, (TrW 2 ) 2 generates gaugino masses that can be hierarchically smaller than the scalar masses, behaving as m 1/2 ∼ m 0 4 in string units. Similarly, ΠTrW 2 generates Dirac masses for non-chiral brane fermions, of the same order of magnitude. This mechanism can be used for instance to obtain fermion masses at the TeV scale for scalar masses as high as m 0 ∼ O (10 13 ) GeV. We present explicit examples in toroidal string compactifications with intersecting D-branes. (author)

  2. 伦理人性——残疾人群众体育价值的归宿%Ethics and Humanity——Value Destination of Mass Physical Culture for the Handicapped

    Institute of Scientific and Technical Information of China (English)

    马飞

    2012-01-01

    The aim of mass physical culture for the handicapped was to help them to recovery to health, to excavate their potentialities, to supply them a stage to participate in social activities, achieve self realization and enjoy equal opportunity. Humanity is the root of mass physical culture, which gets rid of the pursuit of utilitarian, but emphasizes the positive experience of self - presence and participation, focuses humanistic concern, reflects the human nature of the handicapped and their aspiration for returning to normal life.%开展残疾人群众体育目的就是使残疾人的体质尽可能地康复,挖掘他们自身的潜力,为他们提供一个走向社会、实现自我、享受平等机会的舞台.人性是残疾人群众体育产生的根,一切残疾人群众体育活动摒除了功利性的追逐,强调肯定自我存在与参与体验,注重人性关怀思想,反映残疾人人性的本身需要和回归现实的生活追求.

  3. Higher body mass index is associated with higher fractional creatinine excretion in healthy subjects

    NARCIS (Netherlands)

    Sinkeler, Steef J.; Visser, Folkert W.; Krikken, Jan A.; Stegeman, Coen A.; Homan van der Heide, Jaap J.; Navis, Gerjan

    2011-01-01

    Accurate glomerular filtration rate (GFR) measurement in normal to high range is important for epidemiological studies and workup for kidney donation. Creatinine-based equations perform poorly in this GFR range. Creatinine clearance (CrCl) provides a substitute, provided urine is collected

  4. Higher body mass index is associated with higher fractional creatinine excretion in healthy subjects

    NARCIS (Netherlands)

    Sinkeler, Steef J.; Visser, Folkert W.; Krikken, Jan A.; Stegeman, Coen A.; van der Heide, Jaap J. Homan; Navis, Gerjan

    2011-01-01

    Background. Accurate glomerular filtration rate (GFR) measurement in normal to high range is important for epidemiological studies and workup for kidney donation. Creatinine-based equations perform poorly in this GFR range. Creatinine clearance (CrCl) provides a substitute, provided urine is

  5. Atomic masses 1995. The 1995 atomic mass evaluation

    International Nuclear Information System (INIS)

    Audi, G.; Wapstra, A.H.

    1995-01-01

    The 1995 atomic mass evaluation by G. Audi and A.H. Wapstra is documented. The resulting data files containing recommended values of atomic masses, obtained by experiment or systematics, and related data such as reaction and separation energies are described. The data files can be obtained through online services from several nuclear data centers or on magnetic tape, free of charge. (author)

  6. Atomic masses 1993. The 1993 atomic mass evaluation

    International Nuclear Information System (INIS)

    Audi, G.; Wapstra, A.H.

    1993-01-01

    The 1993 atomic mass evaluation by G. Audi and A.H. Wapstra is documented. The resulting data files containing recommended values of atomic masses, obtained by experiment of systematics, and related data such as reaction and separation energies are described. The data files can be obtained through online services from several nuclear data centers or on magnetic tape, free of charge. (author)

  7. Charged gravastars in higher dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Ghosh, S., E-mail: shnkghosh122@gmail.com [Department of Physics, Indian Institute of Engineering Science and Technology, B. Garden, Howrah 711103, West Bengal (India); Rahaman, F., E-mail: rahaman@associates.iucaa.in [Department of Mathematics, Jadavpur University, Kolkata 700032, West Bengal (India); Guha, B.K., E-mail: bkguhaphys@gmail.com [Department of Physics, Indian Institute of Engineering Science and Technology, B. Garden, Howrah 711103, West Bengal (India); Ray, Saibal, E-mail: saibal@associates.iucaa.in [Department of Physics, Government College of Engineering and Ceramic Technology, 73 A.C.B. Lane, Kolkata 700010, West Bengal (India)

    2017-04-10

    We explore possibility to find out a new model of gravastars in the extended D-dimensional Einstein–Maxwell space–time. The class of solutions as obtained by Mazur and Mottola of a neutral gravastar have been observed as a competent alternative to D-dimensional versions of the Schwarzschild–Tangherlini black hole. The outer region of the charged gravastar model therefore corresponds to a higher dimensional Reissner–Nordström black hole. In connection to this junction conditions, therefore we have formulated mass and the related Equation of State of the gravastar. It has been shown that the model satisfies all the requirements of the physical features. However, overall observational survey of the results also provide probable indication of non-applicability of higher dimensional approach for construction of a gravastar with or without charge from an ordinary 4-dimensional seed as far as physical ground is concerned.

  8. Comb-push ultrasound shear elastography of breast masses: initial results show promise.

    Science.gov (United States)

    Denis, Max; Mehrmohammadi, Mohammad; Song, Pengfei; Meixner, Duane D; Fazzio, Robert T; Pruthi, Sandhya; Whaley, Dana H; Chen, Shigao; Fatemi, Mostafa; Alizad, Azra

    2015-01-01

    To evaluate the performance of Comb-push Ultrasound Shear Elastography (CUSE) for classification of breast masses. CUSE is an ultrasound-based quantitative two-dimensional shear wave elasticity imaging technique, which utilizes multiple laterally distributed acoustic radiation force (ARF) beams to simultaneously excite the tissue and induce shear waves. Female patients who were categorized as having suspicious breast masses underwent CUSE evaluations prior to biopsy. An elasticity estimate within the breast mass was obtained from the CUSE shear wave speed map. Elasticity estimates of various types of benign and malignant masses were compared with biopsy results. Fifty-four female patients with suspicious breast masses from our ongoing study are presented. Our cohort included 31 malignant and 23 benign breast masses. Our results indicate that the mean shear wave speed was significantly higher in malignant masses (6 ± 1.58 m/s) in comparison to benign masses (3.65 ± 1.36 m/s). Therefore, the stiffness of the mass quantified by the Young's modulus is significantly higher in malignant masses. According to the receiver operating characteristic curve (ROC), the optimal cut-off value of 83 kPa yields 87.10% sensitivity, 82.61% specificity, and 0.88 for the area under the curve (AUC). CUSE has the potential for clinical utility as a quantitative diagnostic imaging tool adjunct to B-mode ultrasound for differentiation of malignant and benign breast masses.

  9. Comb-push ultrasound shear elastography of breast masses: initial results show promise.

    Directory of Open Access Journals (Sweden)

    Max Denis

    Full Text Available To evaluate the performance of Comb-push Ultrasound Shear Elastography (CUSE for classification of breast masses.CUSE is an ultrasound-based quantitative two-dimensional shear wave elasticity imaging technique, which utilizes multiple laterally distributed acoustic radiation force (ARF beams to simultaneously excite the tissue and induce shear waves. Female patients who were categorized as having suspicious breast masses underwent CUSE evaluations prior to biopsy. An elasticity estimate within the breast mass was obtained from the CUSE shear wave speed map. Elasticity estimates of various types of benign and malignant masses were compared with biopsy results.Fifty-four female patients with suspicious breast masses from our ongoing study are presented. Our cohort included 31 malignant and 23 benign breast masses. Our results indicate that the mean shear wave speed was significantly higher in malignant masses (6 ± 1.58 m/s in comparison to benign masses (3.65 ± 1.36 m/s. Therefore, the stiffness of the mass quantified by the Young's modulus is significantly higher in malignant masses. According to the receiver operating characteristic curve (ROC, the optimal cut-off value of 83 kPa yields 87.10% sensitivity, 82.61% specificity, and 0.88 for the area under the curve (AUC.CUSE has the potential for clinical utility as a quantitative diagnostic imaging tool adjunct to B-mode ultrasound for differentiation of malignant and benign breast masses.

  10. Phenomenological approach to the modelling of elliptical galaxies: The problem of the mass-to-light ratio

    Directory of Open Access Journals (Sweden)

    Samurović S.

    2007-01-01

    Full Text Available In this paper the problem of the phenomenological modelling of elliptical galaxies using various available observational data is presented. Recently, Tortora, Cardona and Piedipalumbo (2007 suggested a double power law expression for the global cumulative mass-to-light ratio of elliptical galaxies. We tested their expression on a sample of ellipticals for which we have the estimates of the mass-to-light ratio beyond ~ 3 effective radii, a region where dark matter is expected to play an important dynamical role. We found that, for all the galaxies in our sample, we have α + β > 0, but that this does not necessarily mean a high dark matter content. The galaxies with higher mass (and higher dark matter content also have higher value of α+β. It was also shown that there is an indication that the galaxies with higher value of the effective radius also have higher dark matter content. .

  11. Comparison of skeletal muscle mass to fat-free mass ratios among different ethnic groups.

    Science.gov (United States)

    Abe, T; Bemben, M G; Kondo, M; Kawakami, Y; Fukunaga, T

    2012-01-01

    Asians seem to have less skeletal muscle mass (SMM) than other ethnic groups, but it is not clear whether relative SMM, i.e., SMM / height square or SMM to fat-free mass (FFM) ratio, differs among different ethnic groups at the same level of body mass index (BMI). To compare the SMM to fat-free mass (FFM) ratio as well as anthropometric variables and body composition among 3 ethnic groups. Three hundred thirty-nine Japanese, 343 Brazilian, and 183 German men and women were recruited for this cross-sectional study. Muscle thickness (MTH) and subcutaneous fat thickness (FTH) were measured by ultrasound at nine sites on the anterior and posterior aspects of the body. FTH was used to estimate the body density, from which fat mass and fat-free mass (FFM) was calculated by using Brozek equation. Total SMM was estimated from ultrasound-derived prediction equations. Percentage body fat was similar among the ethnic groups in men, while Brazilians were higher than Japanese in women. In German men and women, absolute SMM and FFM were higher than in their Japanese and Brazilians counterparts. SMM index and SMM:FFM ratios were similar among the ethnic groups in women, excluding SMM:FFM ratio in Brazilian. In men, however, these relative values (SMM index and SMM:FFM ratio) were still higher in Germans. After adjusting for age and BMI, the SMM index and SMM:FFM ratios were lower in Brazilian men and women compared with the other two ethnic groups, while the SMM index and SMM:FFM ratios were similar in Japanese and German men and women, excluding SMM:FFM ratio in women. Our results suggest that relative SMM is not lower in Asian populations compared with European populations after adjusted by age and BMI.

  12. ON THE MASS DISTRIBUTION AND BIRTH MASSES OF NEUTRON STARS

    International Nuclear Information System (INIS)

    Özel, Feryal; Psaltis, Dimitrios; Santos Villarreal, Antonio; Narayan, Ramesh

    2012-01-01

    We investigate the distribution of neutron star masses in different populations of binaries, employing Bayesian statistical techniques. In particular, we explore the differences in neutron star masses between sources that have experienced distinct evolutionary paths and accretion episodes. We find that the distribution of neutron star masses in non-recycled eclipsing high-mass binaries as well as of slow pulsars, which are all believed to be near their birth masses, has a mean of 1.28 M ☉ and a dispersion of 0.24 M ☉ . These values are consistent with expectations for neutron star formation in core-collapse supernovae. On the other hand, double neutron stars, which are also believed to be near their birth masses, have a much narrower mass distribution, peaking at 1.33 M ☉ , but with a dispersion of only 0.05 M ☉ . Such a small dispersion cannot easily be understood and perhaps points to a particular and rare formation channel. The mass distribution of neutron stars that have been recycled has a mean of 1.48 M ☉ and a dispersion of 0.2 M ☉ , consistent with the expectation that they have experienced extended mass accretion episodes. The fact that only a very small fraction of recycled neutron stars in the inferred distribution have masses that exceed ∼2 M ☉ suggests that only a few of these neutron stars cross the mass threshold to form low-mass black holes.

  13. Neutrino mass?

    International Nuclear Information System (INIS)

    Kayser, B.

    1992-01-01

    After arguing that we should be looking for evidence of neutrino mass, we illustrate the possible consequences of neutrino mass and mixing. We then turn to the question of whether neutrinos are their own antiparticles, and to the process which may answer this question: neutrinoless double beta decay. Next, we review the proposed Mikheyev-Smirnov-Wolfenstein solution to the solar neutrino problem, and discuss models which can generate neutrino electromagnetic moments large enough to play a role in the sun. Finally, we consider how the possible 17 keV neutrino, if real, would fit in with everything we know about neutrinos. (orig.)

  14. Mass metrology

    CERN Document Server

    Gupta, S V

    2012-01-01

    This book presents the practical aspects of mass measurements. Concepts of gravitational, inertial and conventional mass and details of the variation of acceleration of gravity are described. The Metric Convention and International Prototype Kilogram and BIPM standards are described. The effect of change of gravity on the indication of electronic balances is derived with respect of latitude, altitude and earth topography. The classification of weights by OIML is discussed. Maximum permissible errors in different categories of weights prescribed by national and international organizations are p

  15. Bayesian modeling of the mass and density of asteroids

    Science.gov (United States)

    Dotson, Jessie L.; Mathias, Donovan

    2017-10-01

    Mass and density are two of the fundamental properties of any object. In the case of near earth asteroids, knowledge about the mass of an asteroid is essential for estimating the risk due to (potential) impact and planning possible mitigation options. The density of an asteroid can illuminate the structure of the asteroid. A low density can be indicative of a rubble pile structure whereas a higher density can imply a monolith and/or higher metal content. The damage resulting from an impact of an asteroid with Earth depends on its interior structure in addition to its total mass, and as a result, density is a key parameter to understanding the risk of asteroid impact. Unfortunately, measuring the mass and density of asteroids is challenging and often results in measurements with large uncertainties. In the absence of mass / density measurements for a specific object, understanding the range and distribution of likely values can facilitate probabilistic assessments of structure and impact risk. Hierarchical Bayesian models have recently been developed to investigate the mass - radius relationship of exoplanets (Wolfgang, Rogers & Ford 2016) and to probabilistically forecast the mass of bodies large enough to establish hydrostatic equilibrium over a range of 9 orders of magnitude in mass (from planemos to main sequence stars; Chen & Kipping 2017). Here, we extend this approach to investigate the mass and densities of asteroids. Several candidate Bayesian models are presented, and their performance is assessed relative to a synthetic asteroid population. In addition, a preliminary Bayesian model for probablistically forecasting masses and densities of asteroids is presented. The forecasting model is conditioned on existing asteroid data and includes observational errors, hyper-parameter uncertainties and intrinsic scatter.

  16. Higher Order Expectations in Asset Pricing

    OpenAIRE

    Philippe BACCHETTA; Eric VAN WINCOOP

    2004-01-01

    We examine formally Keynes' idea that higher order beliefs can drive a wedge between an asset price and its fundamental value based on expected future payoffs. Higher order expectations add an additional term to a standard asset pricing equation. We call this the higher order wedge, which depends on the difference between higher and first order expectations of future payoffs. We analyze the determinants of this wedge and its impact on the equilibrium price. In the context of a dynamic noisy r...

  17. Mass spectrometry

    DEFF Research Database (Denmark)

    Nyvang Hartmeyer, Gitte; Jensen, Anne Kvistholm; Böcher, Sidsel

    2010-01-01

    Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) is currently being introduced for the rapid and accurate identification of bacteria. We describe 2 MALDI-TOF MS identification cases - 1 directly on spinal fluid and 1 on grown bacteria. Rapidly obtained...

  18. Higher Education and Inequality

    Science.gov (United States)

    Brown, Roger

    2018-01-01

    After climate change, rising economic inequality is the greatest challenge facing the advanced Western societies. Higher education has traditionally been seen as a means to greater equality through its role in promoting social mobility. But with increased marketisation higher education now not only reflects the forces making for greater inequality…

  19. Higher Education in California

    Science.gov (United States)

    Public Policy Institute of California, 2016

    2016-01-01

    Higher education enhances Californians' lives and contributes to the state's economic growth. But population and education trends suggest that California is facing a large shortfall of college graduates. Addressing this short­fall will require strong gains for groups that have been historically under­represented in higher education. Substantial…

  20. Reimagining Christian Higher Education

    Science.gov (United States)

    Hulme, E. Eileen; Groom, David E., Jr.; Heltzel, Joseph M.

    2016-01-01

    The challenges facing higher education continue to mount. The shifting of the U.S. ethnic and racial demographics, the proliferation of advanced digital technologies and data, and the move from traditional degrees to continuous learning platforms have created an unstable environment to which Christian higher education must adapt in order to remain…

  1. Happiness in Higher Education

    Science.gov (United States)

    Elwick, Alex; Cannizzaro, Sara

    2017-01-01

    This paper investigates the higher education literature surrounding happiness and related notions: satisfaction, despair, flourishing and well-being. It finds that there is a real dearth of literature relating to profound happiness in higher education: much of the literature using the terms happiness and satisfaction interchangeably as if one were…

  2. Gender and Higher Education

    Science.gov (United States)

    Bank, Barbara J., Ed.

    2011-01-01

    This comprehensive, encyclopedic review explores gender and its impact on American higher education across historical and cultural contexts. Challenging recent claims that gender inequities in U.S. higher education no longer exist, the contributors--leading experts in the field--reveal the many ways in which gender is embedded in the educational…

  3. Quality of Higher Education

    DEFF Research Database (Denmark)

    Zou, Yihuan

    is about constructing a more inclusive understanding of quality in higher education through combining the macro, meso and micro levels, i.e. from the perspectives of national policy, higher education institutions as organizations in society, individual teaching staff and students. It covers both......Quality in higher education was not invented in recent decades – universities have always possessed mechanisms for assuring the quality of their work. The rising concern over quality is closely related to the changes in higher education and its social context. Among others, the most conspicuous...... changes are the massive expansion, diversification and increased cost in higher education, and new mechanisms of accountability initiated by the state. With these changes the traditional internally enacted academic quality-keeping has been given an important external dimension – quality assurance, which...

  4. Higher English for CFE

    CERN Document Server

    Bridges, Ann; Mitchell, John

    2015-01-01

    A brand new edition of the former Higher English: Close Reading , completely revised and updated for the new Higher element (Reading for Understanding, Analysis and Evaluation) - worth 30% of marks in the final exam!. We are working with SQA to secure endorsement for this title. Written by two highly experienced authors this book shows you how to practice for the Reading for Understanding, Analysis and Evaluation section of the new Higher English exam. This book introduces the terms and concepts that lie behind success and offers guidance on the interpretation of questions and targeting answer

  5. Sports Practice and Bone Mass in Prepubertal Adolescents and Young Adults: A Cross-sectional Analysis

    Directory of Open Access Journals (Sweden)

    Alessandra Madia Mantovani

    Full Text Available Abstract AIM To compare bone mass and body composition variables between adolescents engaged in high-impact sports and adults who were sedentary during early life. METHOD A cross-sectional study with 155 participants (64 adolescents and 91 adults aged between 11 and 50 years old. Among the adults, history of sports was evaluated during face-to-face interviews, and information regarding the adolescents' training routines was provided by their coaches. Body composition was evaluated using Dual Energy X-Ray Absorptiometry which provided data about bone mineral density (BMD, bone mineral content (BMC, fat mass (FM, and free fat mass (FFM. RESULTS Adults who engaged in sports practice during early life had higher values of BMC (ES-r = 0.063, FFM (ES-r = 0.391, and lower values of FM (ES-r = 0.396 than sedentary adults. Higher values of BMC (ES-r = 0.063 and BMD in lower limbs (ES-r = 0.091 were observed in active adolescents. Adolescents engaged in sports and adults who were sedentary in early life presented similar values in all bone variables, FM, and FFM. CONCLUSIONS Sports involvement in early life is related to higher bone mass in adulthood. Adolescents engaged in sports presented similar bone mass to adults who had been sedentary in early life.

  6. Maximum mass of magnetic white dwarfs

    International Nuclear Information System (INIS)

    Paret, Daryel Manreza; Horvath, Jorge Ernesto; Martínez, Aurora Perez

    2015-01-01

    We revisit the problem of the maximum masses of magnetized white dwarfs (WDs). The impact of a strong magnetic field on the structure equations is addressed. The pressures become anisotropic due to the presence of the magnetic field and split into parallel and perpendicular components. We first construct stable solutions of the Tolman-Oppenheimer-Volkoff equations for parallel pressures and find that physical solutions vanish for the perpendicular pressure when B ≳ 10 13 G. This fact establishes an upper bound for a magnetic field and the stability of the configurations in the (quasi) spherical approximation. Our findings also indicate that it is not possible to obtain stable magnetized WDs with super-Chandrasekhar masses because the values of the magnetic field needed for them are higher than this bound. To proceed into the anisotropic regime, we can apply results for structure equations appropriate for a cylindrical metric with anisotropic pressures that were derived in our previous work. From the solutions of the structure equations in cylindrical symmetry we have confirmed the same bound for B ∼ 10 13 G, since beyond this value no physical solutions are possible. Our tentative conclusion is that massive WDs with masses well beyond the Chandrasekhar limit do not constitute stable solutions and should not exist. (paper)

  7. The impact of Spitzer infrared data on stellar mass estimates - and a revised galaxy stellar mass function at 0 < z < 5

    Science.gov (United States)

    Elsner, F.; Feulner, G.; Hopp, U.

    2008-01-01

    Aims:We estimate stellar masses of galaxies in the high redshift universe with the intention of determining the influence of newly available Spitzer/IRAC infrared data on the analysis. Based on the results, we probe the mass assembly history of the universe. Methods: We use the GOODS-MUSIC catalog, which provides multiband photometry from the U-filter to the 8 μm Spitzer band for almost 15 000 galaxies with either spectroscopic (for ≈7% of the sample) or photometric redshifts, and apply a standard model fitting technique to estimate stellar masses. We than repeat our calculations with fixed photometric redshifts excluding Spitzer photometry and directly compare the outcomes to look for systematic deviations. Finally we use our results to compute stellar mass functions and mass densities up to redshift z = 5. Results: We find that stellar masses tend to be overestimated on average if further constraining Spitzer data are not included into the analysis. Whilst this trend is small up to intermediate redshifts z ⪉ 2.5 and falls within the typical error in mass, the deviation increases strongly for higher redshifts and reaches a maximum of a factor of three at redshift z ≈ 3.5. Thus, up to intermediate redshifts, results for stellar mass density are in good agreement with values taken from literature calculated without additional Spitzer photometry. At higher redshifts, however, we find a systematic trend towards lower mass densities if Spitzer/IRAC data are included.

  8. Planning for Higher Education.

    Science.gov (United States)

    Lindstrom, Caj-Gunnar

    1984-01-01

    Decision processes for strategic planning for higher education institutions are outlined using these parameters: institutional goals and power structure, organizational climate, leadership attitudes, specific problem type, and problem-solving conditions and alternatives. (MSE)

  9. Advert for higher education

    OpenAIRE

    N.V. Provozin; А.S. Teletov

    2011-01-01

    The article discusses the features advertising higher education institution. The analysis results of marketing research students for their choice of institutions and further study. Principles of the advertising campaign on three levels: the university, the faculty, the separate department.

  10. On higher derivative gravity

    International Nuclear Information System (INIS)

    Accioly, A.J.

    1987-01-01

    A possible classical route conducting towards a general relativity theory with higher-derivatives starting, in a sense, from first principles, is analysed. A completely causal vacuum solution with the symmetries of the Goedel universe is obtained in the framework of this higher-derivative gravity. This very peculiar and rare result is the first known vcuum solution of the fourth-order gravity theory that is not a solution of the corresponding Einstein's equations.(Author) [pt

  11. Higher Spins & Strings

    CERN Multimedia

    CERN. Geneva

    2014-01-01

    The conjectured relation between higher spin theories on anti de-Sitter (AdS) spaces and weakly coupled conformal field theories is reviewed. I shall then outline the evidence in favour of a concrete duality of this kind, relating a specific higher spin theory on AdS3 to a family of 2d minimal model CFTs. Finally, I shall explain how this relation fits into the framework of the familiar stringy AdS/CFT correspondence.

  12. Differential diagnosis of adrenal gland masses

    International Nuclear Information System (INIS)

    Szolar, D.H.M.; Unger, B.; Preidler, K.; Ranner, G.; Heinz-Peer, G.

    1999-01-01

    Computed tomography (CT) and magnetic resonance (MR) imaging are first line modalities in the evaluation of patients with adrenal gland masses, and have the potential to be very accurate for the localization of adrenal gland masses in patients with diseases associated with hyperfunctioning conditions of the adrenal gland. Both CT and MR imaging allow a specific diagnosis of acute adrenal hemorrhage, adrenal myelolipoma, and adrenal cysts. CT is also helpful in the assessment of patients with Addision's disease, particularly the subacute from secondary to granulomatous diseases. Quantitative evaluation of adrenal masses on unenhanced CT scans and/or qualitative analysis on chemical-shift MR imaging have been shown to be accurate in distinguishing adrenal adenomas from non-adenomas. Attenuation of 11 HE or less on unenhanced CT scans and/or signal loss on opposed phase MR images indicate adenoma with a high specificity and acceptable sensitivity. More recently, delayed-enhanced CT has yielded higher sensitivity and specificity values in distinguishing between adrenal adenomas and non-adenomas than both unenhanced CT and chemical-shift MR imaging do. On delayed-enhanced CT scans, adrenal adenomas exhibit a greater washout of contrast material than do adrenal non-adenomas. Therefore, adrenal non-adenomas have significantly higher attenuation than adenomas on delayed-enhanced CT scans obtained at several arbitrarily chosen time points (3-60 min) after the initiation of contrast material administration. (orig.) [de

  13. Delocalized SYZ mirrors and confronting top-down SU(3)-structure holographic meson masses at finite g and N{sub c} with P(article) D(ata) G(roup) values

    Energy Technology Data Exchange (ETDEWEB)

    Yadav, Vikas; Sil, Karunava [Indian Institute of Technology, Department of Physics, Roorkee, Uttarakhand (India); Misra, Aalok [Indian Institute of Technology, Department of Physics, Roorkee, Uttarakhand (India); McGill University, Physics Department, Montreal, QC (Canada)

    2017-10-15

    Meson spectroscopy at finite gauge coupling - whereat any perturbative QCD computation would break down - and finite number of colors, from a top-down holographic string model, has thus far been entirely missing in the literature. This paper fills this gap. Using the delocalized type IIA SYZ mirror (with SU(3) structure) of the holographic type IIB dual of large-N thermal QCD of Mia et al. (Nucl Phys B 839:187. arXiv:0902.1540 [hep-th], 2010) as constructed in Dhuria and Misra (JHEP 1311:001. arXiv:1306.4339 [hep-th], 2013) at finite coupling and number of colors (N{sub c} = number of D5(D5)-branes wrapping a vanishing two-cycle in the top-down holographic construct of Mia et al. (Nucl Phys B 839:187. arXiv:0902.1540 [hep-th], 2010) = O(1) in the IR in the MQGP limit of Dhuria and Misra (JHEP 1311:001. arXiv:1306.4339 [hep-th], 2013) at the end of a Seiberg-duality cascade), we obtain analytical (not just numerical) expressions for the vector and scalar meson spectra and compare our results with previous calculations of Sakai and Sugimoto (Prog Theor Phys 113:843. doi:10.1143/PTP.113.843 arXiv:hep-th/0412141, 2005) and Dasgupta et al. (JHEP 1507:122. doi:10.1007/JHEP07(2015)122 arXiv:1409.0559 [hep-th], 2015), and we obtain a closer match with the Particle Data Group (PDG) results of Olive et al. (Particle Data Group) (Chin Phys C 38:090001, 2014). Through explicit computations, we verify that the vector and scalar meson spectra obtained by the gravity dual with a black hole for all temperatures (small and large) are nearly isospectral with the spectra obtained by a thermal gravity dual valid for only low temperatures; the isospectrality is much closer for vector mesons than scalar mesons. The black-hole gravity dual (with a horizon radius smaller than the deconfinement scale) also provides the expected large-N suppressed decrease in vector meson mass with increase of temperature. (orig.)

  14. Delocalized SYZ mirrors and confronting top-down SU(3)-structure holographic meson masses at finite g and N_c with P(article) D(ata) G(roup) values

    Science.gov (United States)

    Yadav, Vikas; Misra, Aalok; Sil, Karunava

    2017-10-01

    Meson spectroscopy at finite gauge coupling - whereat any perturbative QCD computation would break down - and finite number of colors, from a top-down holographic string model, has thus far been entirely missing in the literature. This paper fills this gap. Using the delocalized type IIA SYZ mirror (with SU(3) structure) of the holographic type IIB dual of large- N thermal QCD of Mia et al. (Nucl Phys B 839:187. arXiv:0902.1540 [hep-th], 2010) as constructed in Dhuria and Misra (JHEP 1311:001. arXiv:1306.4339 [hep-th], 2013) at finite coupling and number of colors (N_c = number of D5(\\overline{D5})-branes wrapping a vanishing two-cycle in the top-down holographic construct of Mia et al. (Nucl Phys B 839:187. arXiv:0902.1540 [hep-th], 2010) = O(1) in the IR in the MQGP limit of Dhuria and Misra (JHEP 1311:001. arXiv:1306.4339 [hep-th], 2013) at the end of a Seiberg-duality cascade), we obtain analytical (not just numerical) expressions for the vector and scalar meson spectra and compare our results with previous calculations of Sakai and Sugimoto (Prog Theor Phys 113:843. doi: 10.1143/PTP.113.843 arXiv:hep-th/0412141, 2005) and Dasgupta et al. (JHEP 1507:122. doi: 10.1007/JHEP07(2015)122 arXiv:1409.0559 [hep-th], 2015), and we obtain a closer match with the Particle Data Group (PDG) results of Olive et al. (Particle Data Group) (Chin Phys C 38:090001, 2014). Through explicit computations, we verify that the vector and scalar meson spectra obtained by the gravity dual with a black hole for all temperatures (small and large) are nearly isospectral with the spectra obtained by a thermal gravity dual valid for only low temperatures; the isospectrality is much closer for vector mesons than scalar mesons. The black-hole gravity dual (with a horizon radius smaller than the deconfinement scale) also provides the expected large- N suppressed decrease in vector meson mass with increase of temperature.

  15. Delocalized SYZ mirrors and confronting top-down SU(3)-structure holographic meson masses at finite g and Nc with P(article) D(ata) G(roup) values

    International Nuclear Information System (INIS)

    Yadav, Vikas; Sil, Karunava; Misra, Aalok

    2017-01-01

    Meson spectroscopy at finite gauge coupling - whereat any perturbative QCD computation would break down - and finite number of colors, from a top-down holographic string model, has thus far been entirely missing in the literature. This paper fills this gap. Using the delocalized type IIA SYZ mirror (with SU(3) structure) of the holographic type IIB dual of large-N thermal QCD of Mia et al. (Nucl Phys B 839:187. arXiv:0902.1540 [hep-th], 2010) as constructed in Dhuria and Misra (JHEP 1311:001. arXiv:1306.4339 [hep-th], 2013) at finite coupling and number of colors (N c = number of D5(D5)-branes wrapping a vanishing two-cycle in the top-down holographic construct of Mia et al. (Nucl Phys B 839:187. arXiv:0902.1540 [hep-th], 2010) = O(1) in the IR in the MQGP limit of Dhuria and Misra (JHEP 1311:001. arXiv:1306.4339 [hep-th], 2013) at the end of a Seiberg-duality cascade), we obtain analytical (not just numerical) expressions for the vector and scalar meson spectra and compare our results with previous calculations of Sakai and Sugimoto (Prog Theor Phys 113:843. doi:10.1143/PTP.113.843 arXiv:hep-th/0412141, 2005) and Dasgupta et al. (JHEP 1507:122. doi:10.1007/JHEP07(2015)122 arXiv:1409.0559 [hep-th], 2015), and we obtain a closer match with the Particle Data Group (PDG) results of Olive et al. (Particle Data Group) (Chin Phys C 38:090001, 2014). Through explicit computations, we verify that the vector and scalar meson spectra obtained by the gravity dual with a black hole for all temperatures (small and large) are nearly isospectral with the spectra obtained by a thermal gravity dual valid for only low temperatures; the isospectrality is much closer for vector mesons than scalar mesons. The black-hole gravity dual (with a horizon radius smaller than the deconfinement scale) also provides the expected large-N suppressed decrease in vector meson mass with increase of temperature. (orig.)

  16. Nitrogen regulation of transpiration controls mass-flow acquisition of nutrients.

    Science.gov (United States)

    Matimati, Ignatious; Verboom, G Anthony; Cramer, Michael D

    2014-01-01

    Transpiration may enhance mass-flow of nutrients to roots, especially in low-nutrient soils or where the root system is not extensively developed. Previous work suggested that nitrogen (N) may regulate mass-flow of nutrients. Experiments were conducted to determine whether N regulates water fluxes, and whether this regulation has a functional role in controlling the mass-flow of nutrients to roots. Phaseolus vulgaris were grown in troughs designed to create an N availability gradient by restricting roots from intercepting a slow-release N source, which was placed at one of six distances behind a 25 μm mesh from which nutrients could move by diffusion or mass-flow (termed 'mass-flow' treatment). Control plants had the N source supplied directly to their root zone so that N was available through interception, mass-flow, and diffusion (termed 'interception' treatment). 'Mass-flow' plants closest to the N source exhibited 2.9-fold higher transpiration (E), 2.6-fold higher stomatal conductance (gs), 1.2-fold higher intercellular [CO2] (Ci), and 3.4-fold lower water use efficiency than 'interception' plants, despite comparable values of photosynthetic rate (A). E, gs, and Ci first increased and then decreased with increasing distance from the N source to values even lower than those of 'interception' plants. 'Mass-flow' plants accumulated phosphorus and potassium, and had maximum concentrations at 10mm from the N source. Overall, N availability regulated transpiration-driven mass-flow of nutrients from substrate zones that were inaccessible to roots. Thus when water is available, mass-flow may partially substitute for root density in providing access to nutrients without incurring the costs of root extension, although the efficacy of mass-flow also depends on soil nutrient retention and hydraulic properties.

  17. Classical higher-order processes

    DEFF Research Database (Denmark)

    Montesi, Fabrizio

    2017-01-01

    Classical Processes (CP) is a calculus where the proof theory of classical linear logic types processes à la Π-calculus, building on a Curry-Howard correspondence between session types and linear propositions. We contribute to this research line by extending CP with process mobility, inspired...... by the Higher-Order Π-calculus. The key to our calculus is that sequents are asymmetric: one side types sessions as in CP and the other types process variables, which can be instantiated with process values. The controlled interaction between the two sides ensures that process variables can be used at will......, but always respecting the linear usage of sessions expected by the environment....

  18. [Diffusion weighted imaging and perfusion weighted imaging in the differential diagnosis of benign and malignant renal masses on 3.0 T MRI].

    Science.gov (United States)

    Xu, Xiaowen; Wang, Peijun; Ma, Liang; Shao, Zhihong; Zhang, Min

    2015-01-20

    To explore the value of diffusion weighted imaging (DWI) and perfusion weighted imaging (PWI) in identifying benign and malignant renal masses and differentiating the histological types of renal masses. Fifteen healthy volunteers and 46 patients with renal masses proven by pathology, including clear cell carcinomas (n = 18), papillary carcinomas (n = 8), chromophobe carcinomas (n = 7) and angiomyolipomas (n = 13), were examined with DWI and PWI scan at 3.0 T MRI. ANOVA was employed to compare the values of transfer constant (K(trans)), rate constant of backflux (Kep) and extra-vascular extra-cellular space fractional volume (Ve) proceeded by PWI and the value of ADC resulted from DWI between normal kidney and different histological types of renal masses. Receiver operating characteristics (ROC) curve was used to analyze and compare the diagnostic value of the methods of PWI and DWI in differentiating benign and malignant renal masses. The ADC value of normal renal parenchyma was (2.10 ± 0.24) × 10⁻³ mm²/s, which was statistically higher than benign and malignant renal masses (P 0.05).Values of K(trans), Kep and Ve between normal renal parenchyma and different histological types of renal masses had statistical differences.Values of K(trans) and Ve in three histological types of malignant renal masses were statistically higher than those of benign renal masses.Kep value of clear cell carcinoma was significantly higher than that of benign renal masses (P benign and malignant renal masses. The K(trans) of benign and malignant renal masses had the largest AUC (AUC = 0.937) at a threshold of 0.38/min. And there were a sensitivity of 87.9% and a specificity of 85.7%. The AUC of ADC was 0.823, sensitivity 72.7% and specificity 92.9%. The ADC threshold for differentiating benign from malignant masses was 1.40 × 10⁻³ mm²/s; AUC of Ve 0.803, sensitivity 78.8% and specificity 71.4%, a threshold of 0.29/min; Kep showed lower diagnostic value. 3.0 T MRI DWI and PWI

  19. Fuel Class Higher Alcohols

    KAUST Repository

    Sarathy, Mani

    2016-08-17

    This chapter focuses on the production and combustion of alcohol fuels with four or more carbon atoms, which we classify as higher alcohols. It assesses the feasibility of utilizing various C4-C8 alcohols as fuels for internal combustion engines. Utilizing higher-molecular-weight alcohols as fuels requires careful analysis of their fuel properties. ASTM standards provide fuel property requirements for spark-ignition (SI) and compression-ignition (CI) engines such as the stability, lubricity, viscosity, and cold filter plugging point (CFPP) properties of blends of higher alcohols. Important combustion properties that are studied include laminar and turbulent flame speeds, flame blowout/extinction limits, ignition delay under various mixing conditions, and gas-phase and particulate emissions. The chapter focuses on the combustion of higher alcohols in reciprocating SI and CI engines and discusses higher alcohol performance in SI and CI engines. Finally, the chapter identifies the sources, production pathways, and technologies currently being pursued for production of some fuels, including n-butanol, iso-butanol, and n-octanol.

  20. Batteries. Higher energy density than gasoline?

    International Nuclear Information System (INIS)

    Fischer, Michael; Werber, Mathew; Schwartz, Peter V.

    2009-01-01

    The energy density of batteries is two orders of magnitude below that of liquid fuels. However, this information alone cannot be used to compare batteries to liquid fuels for automobile energy storage media. Because electric motors have a higher energy conversion efficiency and lower mass than combustion engines, they can provide a higher deliverable mechanical energy density than internal combustion for most transportation applications. (author)

  1. Academic Freedom in Higher Education

    Directory of Open Access Journals (Sweden)

    Tokay GEDİKOĞLU

    2013-12-01

    Full Text Available In this study, the concept ‘academic freedom’ is discussed, its implications and value for the academics, institutions of higher education, and the society are focused, and a few suggestions for the Turkish higher education are made. Academic freedom is defined as the freedom of the academic staff to look for and to find the truth in their scientific field, to publish the findings, and to teach these findings to their students without any external intervention. The concept has gained a further definition with inclusion of research activities into academic freedom as part of the reform attempts started in the German higher education in the 19th century. Therefore, academic freedom is at the very core of the missions of the institutions of higher education; that is, teaching-learning and research. On the point of academic staff and their academic activities of the academic freedom, the subjects such as the aim of the course, choosing the teaching materials and textbooks, the lecturer, and the criteria for the measurement and evaluation of the course take place. And he point of research covers the aim of the study, academicians can’t be imposed the involve in an academic and artistic studies that conflict their values and beliefs; researchers should comply with codes of ethical principles and practices during the process of researching; and research outputs should be reported accurately and honestly without any misleading manipulation. Academic freedom does not provide any exemption from accountability in academic activities of the faculty, nor does it provide any right to act against the well-being of the society, current laws and regulations, and codes of ethical principles and practices.

  2. THE MASS DISTRIBUTION OF STELLAR-MASS BLACK HOLES

    International Nuclear Information System (INIS)

    Farr, Will M.; Sravan, Niharika; Kalogera, Vicky; Cantrell, Andrew; Kreidberg, Laura; Bailyn, Charles D.; Mandel, Ilya

    2011-01-01

    We perform a Bayesian analysis of the mass distribution of stellar-mass black holes using the observed masses of 15 low-mass X-ray binary systems undergoing Roche lobe overflow and 5 high-mass, wind-fed X-ray binary systems. Using Markov Chain Monte Carlo calculations, we model the mass distribution both parametrically—as a power law, exponential, Gaussian, combination of two Gaussians, or log-normal distribution—and non-parametrically—as histograms with varying numbers of bins. We provide confidence bounds on the shape of the mass distribution in the context of each model and compare the models with each other by calculating their relative Bayesian evidence as supported by the measurements, taking into account the number of degrees of freedom of each model. The mass distribution of the low-mass systems is best fit by a power law, while the distribution of the combined sample is best fit by the exponential model. This difference indicates that the low-mass subsample is not consistent with being drawn from the distribution of the combined population. We examine the existence of a 'gap' between the most massive neutron stars and the least massive black holes by considering the value, M 1% , of the 1% quantile from each black hole mass distribution as the lower bound of black hole masses. Our analysis generates posterior distributions for M 1% ; the best model (the power law) fitted to the low-mass systems has a distribution of lower bounds with M 1% >4.3 M sun with 90% confidence, while the best model (the exponential) fitted to all 20 systems has M 1% >4.5 M sun with 90% confidence. We conclude that our sample of black hole masses provides strong evidence of a gap between the maximum neutron star mass and the lower bound on black hole masses. Our results on the low-mass sample are in qualitative agreement with those of Ozel et al., although our broad model selection analysis more reliably reveals the best-fit quantitative description of the underlying mass

  3. Higher spin gauge theories

    CERN Document Server

    Henneaux, Marc; Vasiliev, Mikhail A

    2017-01-01

    Symmetries play a fundamental role in physics. Non-Abelian gauge symmetries are the symmetries behind theories for massless spin-1 particles, while the reparametrization symmetry is behind Einstein's gravity theory for massless spin-2 particles. In supersymmetric theories these particles can be connected also to massless fermionic particles. Does Nature stop at spin-2 or can there also be massless higher spin theories. In the past strong indications have been given that such theories do not exist. However, in recent times ways to evade those constraints have been found and higher spin gauge theories have been constructed. With the advent of the AdS/CFT duality correspondence even stronger indications have been given that higher spin gauge theories play an important role in fundamental physics. All these issues were discussed at an international workshop in Singapore in November 2015 where the leading scientists in the field participated. This volume presents an up-to-date, detailed overview of the theories i...

  4. INTERNATIONALIZATION IN HIGHER EDUCATION

    Directory of Open Access Journals (Sweden)

    Catalina Crisan-Mitra

    2016-03-01

    Full Text Available Internationalization of higher education is one of the key trends of development. There are several approaches on how to achieve competitiveness and performance in higher education and international academic mobility; students’ exchange programs, partnerships are some of the aspects that can play a significant role in this process. This paper wants to point out the student’s perception regarding two main directions: one about the master students’ expectation regarding how an internationalized master should be organized and should function, and second the degree of satisfaction of the beneficiaries of internationalized master programs from Babe-Bolyai University. This article is based on an empirical qualitative research that was implemented to students of an internationalized master from the Faculty of Economics and Business Administration. This research can be considered a useful example for those preoccupied to increase the quality of higher education and conclusions drawn have relevance both theoretically and especially practically.

  5. Quality of Higher Education

    DEFF Research Database (Denmark)

    Zou, Yihuan; Zhao, Yingsheng; Du, Xiangyun

    . This transformation involves a broad scale of change at individual level, organizational level, and societal level. In this change process in higher education, staff development remains one of the key elements for university innovation and at the same time demands a systematic and holistic approach.......This paper starts with a critical approach to reflect on the current practice of quality assessment and assurance in higher education. This is followed by a proposal that in response to the global challenges for improving the quality of higher education, universities should take active actions...... of change by improving the quality of teaching and learning. From a constructivist perspective of understanding education and learning, this paper also discusses why and how universities should give more weight to learning and change the traditional role of teaching to an innovative approach of facilitation...

  6. Mass Sports

    Directory of Open Access Journals (Sweden)

    Elena Grigoryeva

    2017-03-01

    Fitness has become one of the most popular kinds of the mass sport and has completely replaced the traditional “physical culture”. Dozens of variations of fitness and millions of participants pose a great challenge to contemporary architecture. The articles of our issue show the present and the future of architecture for fitness. We present a topical collection with a wide geographical range, including the Irkutsk Agglomeration, Tomsk, Krasnodar, sports in the Moscow Palace of Young Pioneers, and the anthology of the top foreign sports venues.

  7. Critical Mass

    CERN Multimedia

    AUTHOR|(CDS)2070299

    2017-01-01

    Critical Mass is a cycling event typically held on the last Friday of every month; its purpose is not usually formalized beyond the direct action of meeting at a set location and time and traveling as a group through city or town streets on bikes. The event originated in 1992 in San Francisco; by the end of 2003, the event was being held in over 300 cities around the world. At CERN it is held once a year in conjunction with the national Swiss campaing "Bike to work".

  8. Reputation in Higher Education

    DEFF Research Database (Denmark)

    Martensen, Anne; Grønholdt, Lars

    2005-01-01

    leaders of higher education institutions to set strategic directions and support their decisions in an effort to create even better study programmes with a better reputation. Finally, managerial implications and directions for future research are discussed.Keywords: Reputation, image, corporate identity......The purpose of this paper is to develop a reputation model for higher education programmes, provide empirical evidence for the model and illustrate its application by using Copenhagen Business School (CBS) as the recurrent case. The developed model is a cause-and-effect model linking image...

  9. Reputation in Higher Education

    DEFF Research Database (Denmark)

    Plewa, Carolin; Ho, Joanne; Conduit, Jodie

    2016-01-01

    Reputation is critical for institutions wishing to attract and retain students in today's competitive higher education setting. Drawing on the resource based view and configuration theory, this research proposes that Higher Education Institutions (HEIs) need to understand not only the impact...... of independent resources but of resource configurations when seeking to achieve a strong, positive reputation. Utilizing fuzzy set qualitative comparative analysis (fsQCA), the paper provides insight into different configurations of resources that HEIs can utilize to build their reputation within their domestic...

  10. Navigating in higher education

    DEFF Research Database (Denmark)

    Thingholm, Hanne Balsby; Reimer, David; Keiding, Tina Bering

    Denne rapport er skrevet på baggrund af spørgeskemaundersøgelsen – Navigating in Higher Education (NiHE) – der rummer besvarelser fra 1410 bachelorstuderende og 283 undervisere fordelt på ni uddannelser fra Aarhus Universitet: Uddannelsesvidenskab, Historie, Nordisk sprog og litteratur, Informati......Denne rapport er skrevet på baggrund af spørgeskemaundersøgelsen – Navigating in Higher Education (NiHE) – der rummer besvarelser fra 1410 bachelorstuderende og 283 undervisere fordelt på ni uddannelser fra Aarhus Universitet: Uddannelsesvidenskab, Historie, Nordisk sprog og litteratur...

  11. CT and MRI diagnosis of tubo-ovarian masses

    International Nuclear Information System (INIS)

    Xiong Minghui; Zhang Wanshi; Wang Dong

    2000-01-01

    Objective: To evaluate the diagnostic value of CT and MRI in tubo-ovarian masses. Methods: CT scan was performed in 67 patients with tubo-ovarian masses confirmed by pathology. 19 of them underwent MRI. Results: (1) 20 primary malignant ovarian tumors showed cystic,solid or cystic-solid masses; papillary projections on cystic wall; pelvic organs and pelvic wall invasion. Chocolate cysts with malignant degeneration exhibited small nodules on thickened cystic wall on CT and MRI. T 1 WI was better for revealing the lesions. (2) Of 11 cases of metastasis to tubo-ovary, 4 showed peritoneal linear enhancement. (3) There were 9 cystadenomas and 2 adenofibromas, one of the cystadenomas contained fat, two adenofibromas were similar to uterus in density on CT while showing lower signal intensity on MRI (both T 1 WI and T 2 WI). (4) Three cases of thecoma exhibited cystic or solid masses, solid thecomas revealed granular enhancement. (5) Teratomas were most specific, one of them was associated with thecoma. (6) Tubo-ovarian abscesses and tuberculosis depicted cystic or cystic-solid masses. (7) Two cases of tubal pregnancy showed inhomogeneous soft tissue masses, the lower density areas in the centers were clot and organized tissues confirmed by pathology. Conclusion: (1) CT and MRI had higher sensitivity but lower specificity for tubo-ovarian masses, the diagnosis should be combined with clinical history and patients' age. (2) Tumors of two different types may coexist and sometimes fat may be present in tumors other than teratoma

  12. R-values

    International Nuclear Information System (INIS)

    Roberts, K.

    2009-01-01

    I'll try to keep this short and simple. R LANL = (beta cpm of X exp on system 'A')/ (beta cpm of 99 Mo exp on system 'A')/ (beta cpm of X on system 'A', from thermal on 235 U)/ (beta cpm of 99 Mo on system 'A', from thermal on 235 U). As I understand it, the above equation is the historical (as well as current) way of determining R-values using data from beta counting at LANL. The ratio in the denominator, a little 'r', is the 'baseline' or 'calibration' value for a specific beta detector. Over time, if the detector 'drifts' one would see a variation in this 'r' during a thermal calibration measurement. This baseline is what LANL likes to track to monitor specific detector performance - this is not relevant to LLNL where gamma detection is used for determining R-values. LANL states that uncertainty is only dependent upon the count statistics for the isotopes measured. If one tries to convert this to an atom basis, the uncertainties will increase due to the incorporation of the uncertainties in the nuclear data used to convert the cpm to atoms. LLNL switched to gamma detection methods in the 1970s thus replacing our beta counting effort. The equation below is how we have since determined R-values. The numerator ratios atom values of isotopes that are determined by measuring gamma cpm (usually? using several peaks per isotope) and then converting to particle decay in dpm using detector efficiency for each peak and the appropriate branch ratio for each gamma emission. Isotope decay is then converted to atoms using specific activity, mass or volume?, and Avogadro's number. The denominator is simply the ratio of published, cumulative fission product chain yields for isotopes produced in a thermal irradiation on 235U - values of England and Ryder are used by LLNL for the NTNF program. Uncertainties in LLNL R-values are dependent upon gamma counting statistics as well as the nuclear data for each isotope. R LLNL = (Atoms of X exp )/(Atoms of 99 Mo exp )/(Cumulative

  13. Asian Women in Higher Education: Shared Communities

    Science.gov (United States)

    Bhopal, Kalwant

    2010-01-01

    More Asian women are entering higher education in the UK than ever before, and the number looks likely to rise. Their engagement with higher education reflects widespread changes in the attitudes and cultural expectations of their various communities, as awareness grows of the greater long-term value associated with continuing in education. Today…

  14. Exploring Higher Thinking.

    Science.gov (United States)

    Conover, Willis M.

    1992-01-01

    Maintains that the social studies reform movement includes a call for the de-emphasis of rote memory and more attention to the development of higher-order thinking skills. Discusses the "thinking tasks" concept derived from the work of Hilda Taba and asserts that the tasks can be used with almost any social studies topic. (CFR)

  15. Higher-Order Hierarchies

    DEFF Research Database (Denmark)

    Ernst, Erik

    2003-01-01

    This paper introduces the notion of higher-order inheritance hierarchies. They are useful because they provide well-known benefits of object-orientation at the level of entire hierarchies-benefits which are not available with current approaches. Three facets must be adressed: First, it must be po...

  16. Inflation from higher dimensions

    International Nuclear Information System (INIS)

    Shafi, Q.

    1987-01-01

    We argue that an inflationary phase in the very early universe is related to the transition from a higher dimensional to a four-dimensional universe. We present details of a previously considered model which gives sufficient inflation without fine tuning of parameters. (orig.)

  17. Higher Education Funding Formulas.

    Science.gov (United States)

    McKeown-Moak, Mary P.

    1999-01-01

    One of the most critical components of the college or university chief financial officer's job is budget planning, especially using formulas. A discussion of funding formulas looks at advantages, disadvantages, and types of formulas used by states in budgeting for higher education, and examines how chief financial officers can position the campus…

  18. Liberty and Higher Education.

    Science.gov (United States)

    Thompson, Dennis F.

    1989-01-01

    John Stuart Mill's principle of liberty is discussed with the view that it needs to be revised to guide moral judgments in higher education. Three key elements need to be modified: the action that is constrained; the constraint on the action; and the agent whose action is constrained. (MLW)

  19. Fuel Class Higher Alcohols

    KAUST Repository

    Sarathy, Mani

    2016-01-01

    This chapter focuses on the production and combustion of alcohol fuels with four or more carbon atoms, which we classify as higher alcohols. It assesses the feasibility of utilizing various C4-C8 alcohols as fuels for internal combustion engines

  20. Evaluation in Higher Education

    Science.gov (United States)

    Bognar, Branko; Bungic, Maja

    2014-01-01

    One of the means of transforming classroom experience is by conducting action research with students. This paper reports about the action research with university students. It has been carried out within a semester of the course "Methods of Upbringing". Its goal has been to improve evaluation of higher education teaching. Different forms…

  1. Higher-level Innovization

    DEFF Research Database (Denmark)

    Bandaru, Sunith; Tutum, Cem Celal; Deb, Kalyanmoy

    2011-01-01

    we introduce the higher-level innovization task through an application of a manufacturing process simulation for the Friction Stir Welding (FSW) process where commonalities among two different Pareto-optimal fronts are analyzed. Multiple design rules are simultaneously deciphered from each front...

  2. Benchmarking for Higher Education.

    Science.gov (United States)

    Jackson, Norman, Ed.; Lund, Helen, Ed.

    The chapters in this collection explore the concept of benchmarking as it is being used and developed in higher education (HE). Case studies and reviews show how universities in the United Kingdom are using benchmarking to aid in self-regulation and self-improvement. The chapters are: (1) "Introduction to Benchmarking" (Norman Jackson…

  3. Creativity in Higher Education

    Science.gov (United States)

    Gaspar, Drazena; Mabic, Mirela

    2015-01-01

    The paper presents results of research related to perception of creativity in higher education made by the authors at the University of Mostar from Bosnia and Herzegovina. This research was based on a survey conducted among teachers and students at the University. The authors developed two types of questionnaires, one for teachers and the other…

  4. California's Future: Higher Education

    Science.gov (United States)

    Johnson, Hans

    2015-01-01

    California's higher education system is not keeping up with the changing economy. Projections suggest that the state's economy will continue to need more highly educated workers. In 2025, if current trends persist, 41 percent of jobs will require at least a bachelor's degree and 36 percent will require some college education short of a bachelor's…

  5. Cyberbullying in Higher Education

    Science.gov (United States)

    Minor, Maria A.; Smith, Gina S.; Brashen, Henry

    2013-01-01

    Bullying has extended beyond the schoolyard into online forums in the form of cyberbullying. Cyberbullying is a growing concern due to the effect on its victims. Current studies focus on grades K-12; however, cyberbullying has entered the world of higher education. The focus of this study was to identify the existence of cyberbullying in higher…

  6. Competitiveness - higher education

    Directory of Open Access Journals (Sweden)

    Labas Istvan

    2016-03-01

    Full Text Available Involvement of European Union plays an important role in the areas of education and training equally. The member states are responsible for organizing and operating their education and training systems themselves. And, EU policy is aimed at supporting the efforts of member states and trying to find solutions for the common challenges which appear. In order to make our future sustainable maximally; the key to it lies in education. The highly qualified workforce is the key to development, advancement and innovation of the world. Nowadays, the competitiveness of higher education institutions has become more and more appreciated in the national economy. In recent years, the frameworks of operation of higher education systems have gone through a total transformation. The number of applying students is continuously decreasing in some European countries therefore only those institutions can “survive” this shortfall, which are able to minimize the loss of the number of students. In this process, the factors forming the competitiveness of these budgetary institutions play an important role from the point of view of survival. The more competitive a higher education institution is, the greater the chance is that the students would like to continue their studies there and thus this institution will have a greater chance for the survival in the future, compared to ones lagging behind in the competition. Aim of our treatise prepared is to present the current situation and main data of the EU higher education and we examine the performance of higher education: to what extent it fulfils the strategy for smart, sustainable and inclusive growth which is worded in the framework of Europe 2020 programme. The treatise is based on analysis of statistical data.

  7. Metrology for stable isotope reference materials: 13C/12C and 18O/16O isotope ratio value assignment of pure carbon dioxide gas samples on the Vienna PeeDee Belemnite-CO2 scale using dual-inlet mass spectrometry.

    Science.gov (United States)

    Srivastava, Abneesh; Michael Verkouteren, R

    2018-05-25

    Isotope ratio measurements have been conducted on a series of isotopically distinct pure CO 2 gas samples using the technique of dual-inlet isotope ratio mass spectrometry (DI-IRMS). The influence of instrumental parameters, data normalization schemes on the metrological traceability and uncertainty of the sample isotope composition have been characterized. Traceability to the Vienna PeeDee Belemnite(VPDB)-CO 2 scale was realized using the pure CO 2 isotope reference materials(IRMs) 8562, 8563, and 8564. The uncertainty analyses include contributions associated with the values of iRMs and the repeatability and reproducibility of our measurements. Our DI-IRMS measurement system is demonstrated to have high long-term stability, approaching a precision of 0.001 parts-per-thousand for the 45/44 and 46/44 ion signal ratios. The single- and two-point normalization bias for the iRMs were found to be within their published standard uncertainty values. The values of 13 C/ 12 C and 18 O/ 16 O isotope ratios are expressed relative to VPDB-CO 2 using the [Formula: see text] and [Formula: see text] notation, respectively, in parts-per-thousand (‰ or per mil). For the samples, value assignments between (-25 to +2) ‰ and (-33 to -1) ‰ with nominal combined standard uncertainties of (0.05, 0.3) ‰ for [Formula: see text] and [Formula: see text], respectively were obtained. These samples are used as laboratory reference to provide anchor points for value assignment of isotope ratios (with VPDB traceability) to pure CO 2 samples. Additionally, they serve as potential parent isotopic source material required for the development of gravimetric based iRMs of CO 2 in CO 2 -free dry air in high pressure gas cylinder packages at desired abundance levels and isotopic composition values. Graphical abstract CO 2 gas isotope ratio metrology.

  8. Theoretical Re-evaluations of Scaling Relations between SMBHs and Their Host Galaxies—1. Effect of Seed BH Mass

    Energy Technology Data Exchange (ETDEWEB)

    Shirakata, Hikari [Department of Cosmosciences, Graduate School of Science, Hokkaido University, Sapporo (Japan); Kawaguchi, Toshihiro [Department of Economics, Management and Information Science, Onomichi City University, Onomichi (Japan); Okamoto, Takashi [Department of Cosmosciences, Graduate School of Science, Hokkaido University, Sapporo (Japan); Makiya, Ryu [Kavli Institute for the Physics and Mathematics of the Universe, Todai Institutes for Advanced Study, University of Tokyo, Kashiwa (Japan); Max-Planck-Institut fur Astrophysik, Garching (Germany); Ishiyama, Tomoaki [Institute of Management and Information Technologies, Chiba University, Chiba (Japan); Matsuoka, Yoshiki [Research Center for Space and Cosmic Evolution, Ehime University, Matsuyama (Japan); Nagashima, Masahiro [Faculty of Education, Bunkyo University, Koshigaya (Japan); Enoki, Motohiro [Faculty of Business Administration, Tokyo Keizai University, Kokubunji (Japan); Oogi, Taira [Kavli Institute for the Physics and Mathematics of the Universe, Todai Institutes for Advanced Study, University of Tokyo, Kashiwa (Japan); Kobayashi, Masakazu A. R., E-mail: shirakata@astro1.sci.hokudai.ac.jp [Faculty of Natural Sciences, National Institute of Technology, Kure College, Kure (Japan)

    2017-09-21

    We use a semi-analytic model of galaxy formation and investigate how the mass of a seed black hole affect the scaling relation between black hole mass and bulge mass at z ~ 0. When the mass of the seed is set at 10{sup 5}M{sub ⊙}, we find that the model results become inconsistent with recent observational results of the scaling relation for dwarf galaxies. On the other hand, when we set seed black hole mass as 10{sup 3}M{sub ⊙} or as randomly chosen value within a 10{sup 3-5}M{sub ⊙} range, we find the results are consistent with observational results including the dispersion. We also find that black hole mass—bulge mass relations for less massive bulges at z ~ 0 put stronger constraints on the seed BH mass than the relations at higher redshifts.

  9. Spectroscopy of higher bottomonia

    Directory of Open Access Journals (Sweden)

    Ferretti J.

    2015-01-01

    Full Text Available In this contribution, we discuss our recent unquenched quark model results for the spectrum of bb̄ mesons with self energy corrections, due to the coupling to the meson-meson continuum. Our unquenched quark model predictions for the masses of the recently discovered χb(3P states are compared to those of a re-fit of Godfrey and Isgur’s relativized quark model to the most recent experimental data. The possible importance of continuum effects in the χb(3P states is discussed. Finally, we show our quark model results for the radiative decays of the χb(3P system and the open-bottom decays of bb̄ mesons.

  10. Maternal obesity, gestational weight gain and childhood cardiac outcomes: role of childhood body mass index.

    Science.gov (United States)

    Toemen, L; Gishti, O; van Osch-Gevers, L; Steegers, E A P; Helbing, W A; Felix, J F; Reiss, I K M; Duijts, L; Gaillard, R; Jaddoe, V W V

    2016-07-01

    Maternal obesity may affect cardiovascular outcomes in the offspring. We examined the associations of maternal prepregnancy body mass index and gestational weight gain with childhood cardiac outcomes and explored whether these associations were explained by parental characteristics, infant characteristics or childhood body mass index. In a population-based prospective cohort study among 4852 parents and their children, we obtained maternal weight before pregnancy and in early, mid- and late pregnancy. At age 6 years, we measured aortic root diameter (cm) and left ventricular dimensions. We calculated left ventricular mass (g), left ventricular mass index (g m(-2.7)), relative wall thickness ((2 × left ventricular posterior wall thickness)/left ventricular diameter), fractional shorting (%), eccentric left ventricular hypertrophy and concentric remodeling. A one standard deviation score (SDS) higher maternal prepregnancy body mass index was associated with higher left ventricular mass (0.10 SDS (95% confidence interval (CI) 0.08, 0.13)), left ventricular mass index (0.06 SDS (95% CI 0.03, 0.09)) and aortic root diameter (0.09 SDS (95% CI 0.06, 0.12)), but not with relative wall thickness or fractional shortening. A one SDS higher maternal prepregnancy body mass index was associated with an increased risk of eccentric left ventricular hypertrophy (odds ratio 1.21 (95% CI 1.03, 1.41)), but not of concentric remodeling. When analyzing the effects of maternal weight in different periods simultaneously, only maternal prepregnancy weight and early pregnancy weight were associated with left ventricular mass, left ventricular mass index and aortic root diameter (P-valuesMaternal prepregnancy body mass index and weight gain in early pregnancy are both associated with offspring cardiac structure in childhood, but these associations seem to be fully explained by childhood body mass index.

  11. Effects of BMI, Fat Mass, and Lean Mass on Asthma in Childhood: A Mendelian Randomization Study

    Science.gov (United States)

    Granell, Raquel; Henderson, A. John; Evans, David M.; Smith, George Davey; Ness, Andrew R.; Lewis, Sarah; Palmer, Tom M.; Sterne, Jonathan A. C.

    2014-01-01

    Background Observational studies have reported associations between body mass index (BMI) and asthma, but confounding and reverse causality remain plausible explanations. We aim to investigate evidence for a causal effect of BMI on asthma using a Mendelian randomization approach. Methods and Findings We used Mendelian randomization to investigate causal effects of BMI, fat mass, and lean mass on current asthma at age 7½ y in the Avon Longitudinal Study of Parents and Children (ALSPAC). A weighted allele score based on 32 independent BMI-related single nucleotide polymorphisms (SNPs) was derived from external data, and associations with BMI, fat mass, lean mass, and asthma were estimated. We derived instrumental variable (IV) estimates of causal risk ratios (RRs). 4,835 children had available data on BMI-associated SNPs, asthma, and BMI. The weighted allele score was strongly associated with BMI, fat mass, and lean mass (all p-valuesBMI on asthma was 1.55 (95% CI 1.16–2.07) per kg/m2, p = 0.003. This effect appeared stronger for non-atopic (1.90, 95% CI 1.19–3.03) than for atopic asthma (1.37, 95% CI 0.89–2.11) though there was little evidence of heterogeneity (p = 0.31). The estimated causal RRs for the effects of fat mass and lean mass on asthma were 1.41 (95% CI 1.11–1.79) per 0.5 kg and 2.25 (95% CI 1.23–4.11) per kg, respectively. The possibility of genetic pleiotropy could not be discounted completely; however, additional IV analyses using FTO variant rs1558902 and the other BMI-related SNPs separately provided similar causal effects with wider confidence intervals. Loss of follow-up was unlikely to bias the estimated effects. Conclusions Higher BMI increases the risk of asthma in mid-childhood. Higher BMI may have contributed to the increase in asthma risk toward the end of the 20th century. Please see later in the article for the Editors' Summary PMID:24983943

  12. Radiosensitivity of higher plants

    International Nuclear Information System (INIS)

    Feng Zhijie

    1992-11-01

    The general views on radiosensitivity of higher plants have been introduced from published references. The radiosensitivity varies with species, varieties and organs or tissues. The main factors of determining the radiosensitivity in different species are nucleus volume, chromosome volume, DNA content and endogenous compounds. The self-repair ability of DNA damage and chemical group of biological molecules, such as -SH thiohydroxy of proteins, are main factors to determine the radiosensitivity in different varieties. The moisture, oxygen, temperature radiosensitizer and protector are important external factors for radiosensitivity. Both the multiple target model and Chadwick-Leenhouts model are ideal mathematical models for describing the radiosensitivity of higher plants and the latter has more clear significance in biology

  13. Higher Education Language Policy

    DEFF Research Database (Denmark)

    Lauridsen, Karen M.

    2013-01-01

    Summary of recommendations HEIs are encouraged, within the framework of their own societal context, mission, vision and strategies, to develop the aims and objectives of a Higher Education Language Policy (HELP) that allows them to implement these strategies. In this process, they may want......: As the first step in a Higher Education Language Policy, HEIs should determine the relative status and use of the languages employed in the institution, taking into consideration the answers to the following questions:  What is/are the official language(s) of the HEI?  What is/are the language...... and the level of internationalisation the HEI has or wants to have, and as a direct implication of that, what are the language proficiency levels expected from the graduates of these programme?  Given the profile of the HEI and its educational strategies, which language components are to be offered within...

  14. Fermion masses and Higgs physics in grand unified theories

    Energy Technology Data Exchange (ETDEWEB)

    Bhatti, Abdul Aziz

    2010-03-12

    The Standard model of particle physics is a very successful theory of strong weak and electromagnetic interactions. This theory is perturbative at sufficiently high energies and renormalizable thus it describes these interactions at quantum level. However it has a number of limitations, one being the fact that it has 28 free parameters assuming massive neutrinos. Within the Standard model these parameters can not be explained, however they can be accommodated in the standard theory. Particularly the masses of the fermions are not predicted by the theory. The existence of the neutrino masses can be regarded as the first glimpse of the physics beyond the standard model. In this thesis we have described the quark and lepton masses and mixings in context of non-SUSY SO(10) and four zero texture (FZT). In the four zero texture case the fermion masses and mixing can be related. We have made some predictions using tribimaximal mixing, the near tribimaximal (TBM) mixing and the triminimal parameterization. Our results show that under the TBM the neutrinos have normal, but weak hierarchy. Under near tribimaximal mixing and the triminimal parameterization we find that the neutrino masses in general increase, if the value of solar angle increases from its TBM value and vice versa. It appears that the neutrinos become more and more degenerate for solar angle values higher than TBM value and hierarchical for lower values of solar angle. We also briefly discuss neutrino parameters in the SUSY SO(10) theories. An overview of SUSY SO(10) theories and proton decay is also presented. (orig.)

  15. High-Resolution Mass Spectrometers

    Science.gov (United States)

    Marshall, Alan G.; Hendrickson, Christopher L.

    2008-07-01

    Over the past decade, mass spectrometry has been revolutionized by access to instruments of increasingly high mass-resolving power. For small molecules up to ˜400 Da (e.g., drugs, metabolites, and various natural organic mixtures ranging from foods to petroleum), it is possible to determine elemental compositions (CcHhNnOoSsPp…) of thousands of chemical components simultaneously from accurate mass measurements (the same can be done up to 1000 Da if additional information is included). At higher mass, it becomes possible to identify proteins (including posttranslational modifications) from proteolytic peptides, as well as lipids, glycoconjugates, and other biological components. At even higher mass (˜100,000 Da or higher), it is possible to characterize posttranslational modifications of intact proteins and to map the binding surfaces of large biomolecule complexes. Here we review the principles and techniques of the highest-resolution analytical mass spectrometers (time-of-flight and Fourier transform ion cyclotron resonance and orbitrap mass analyzers) and describe some representative high-resolution applications.

  16. Maximally twisted mass lattice QCD at the physical pion mass

    International Nuclear Information System (INIS)

    Kostrzewa, Bartosz

    2016-01-01

    In computer simulations of Lattice Quantum Chromodynamics, the usage of unphysically large quark masses and the subsequent extrapolation of results to the physical value of the quark masses are major sources of systematic uncertainty. In this thesis, the feasibility and practicality of numerical simulations of Quantum Chromodynamics with physically light up and down quarks using the Wilson twisted mass quark discretisation are explored. Working in this regime is complicated firstly by the numerical expense of these simulations and secondly by the presence of potentially large lattice artefacts. The twisted mass discretisation is affected by an unphysical mass difference between the charged and neutral pions, rendering simulations at the physical charged pion mass infeasible if this mass splitting is too large. With the aim of reducing it, the Sheikholeslami-Wohlert term is added to the twisted mass fermion action and simulations with mass degenerate up and down quarks are then performed as a proof of concept. It is demonstrated that these simulations are stable and that the parameters of the lattice theory can be successfully tuned to correspond to the physical charged pion mass. Subsequently, the parameter tuning for simulations with mass degenerate up and down quarks as well as strange and charm quarks is explored and it is shown that it can be carried out in steps. As benchmark observables, the masses and decay constants of pseudoscalar mesons with light, strange and charm valence quarks are calculated and seen to largely reproduce their phenomenological values, even though continuum and infinite volume extrapolations are not performed. Light, strange and charm quark mass estimates are determined based on this data and also seen to coincide with phenomenological and other lattice determinations. In this analysis, a particular emphasis is placed on the systematic error due to the choice of fit range for pseudoscalar correlation functions and a weighting method is

  17. Use value, exchange value, and resource scarcity

    International Nuclear Information System (INIS)

    Stern, D.I.

    1999-01-01

    The literature on natural resource scarcity indicators is reviewed. Scarcity indicators can be classified by what is being measured: value of the resource stock or value of extracted resource commodities; whose value is considered: social vs. private scarcity; and by the mode of valuation considered: exchange value and use value. Prices and rents are common measures of exchange value or indicators of ''exchange scarcity'' and unit costs can be seen as use value indicators or indicators of u se scarcity . The major aim of this paper is to demonstrate the links between productivity indicators such as unit costs and the classical concept of use value. The two classes of indicator relate to John Commons' discussions of scarcity and efficiency, and a marginal vs. a non-marginal approach to value and scarcity. The classical use value concept also has wider relevance for issues of valuation in energy, resource, and environmental policy. (author)

  18. Gap Analysis: Application to Earned Value Analysis

    OpenAIRE

    Langford, Gary O.; Franck, Raymond (Chip)

    2008-01-01

    Sponsored Report (for Acquisition Research Program) Earned Value is regarded as a useful tool to monitor commercial and defense system acquisitions. This paper applies the theoretical foundations and systematics of Gap Analysis to improve Earned Value Management. As currently implemented, Earned Value inaccurately provides a higher value for the work performed. This preliminary research indicates that Earned Value calculations can be corrected. Value Analysis, properly defined and enacted,...

  19. Assessing the ACEJMC Professional Values and Competencies

    Science.gov (United States)

    Christ, William G.; Henderson, Jennifer J.

    2014-01-01

    The accrediting body for media education, the Accrediting Council on Education in Journalism and Mass Communications (ACEJMC), has established twelve professional values and competencies that all students must demonstrate before graduating from accredited journalism and mass communication programs. A close reading suggests that these twelve…

  20. Operators and higher genus mirror curves

    Energy Technology Data Exchange (ETDEWEB)

    Codesido, Santiago [Département de Physique Théorique et section de Mathématiques,Université de Genève,Genève, CH-1211 (Switzerland); Gu, Jie [Laboratoire de Physique Théorique de l’École Normale Supérieure,CNRS, PSL Research University,Sorbonne Universités, UPMC, 75005 Paris (France); Mariño, Marcos [Département de Physique Théorique et section de Mathématiques,Université de Genève,Genève, CH-1211 (Switzerland)

    2017-02-17

    We perform further tests of the correspondence between spectral theory and topological strings, focusing on mirror curves of genus greater than one with nontrivial mass parameters. In particular, we analyze the geometry relevant to the SU(3) relativistic Toda lattice, and the resolved ℂ{sup 3}/ℤ{sub 6} orbifold. Furthermore, we give evidence that the correspondence holds for arbitrary values of the mass parameters, where the quantization problem leads to resonant states. We also explore the relation between this correspondence and cluster integrable systems.

  1. Higher insulin sensitivity in vegans is not associated with higher mitochondrial density.

    Science.gov (United States)

    Gojda, J; Patková, J; Jaček, M; Potočková, J; Trnka, J; Kraml, P; Anděl, M

    2013-12-01

    Vegans have a lower incidence of insulin resistance (IR)-associated diseases and a higher insulin sensitivity (IS) compared with omnivores. The aim of this study was to examine whether the higher IS in vegans relates to markers of mitochondrial biogenesis and to intramyocellular lipid (IMCL) content. Eleven vegans and 10 matched (race, age, sex, body mass index, physical activity and energy intake) omnivorous controls were enrolled in a case-control study. Anthropometry, bioimpedance (BIA), ultrasound measurement of visceral and subcutaneous fat layer, parameters of glucose and lipid homeostasis, hyperinsulinemic euglycemic clamp and muscle biopsies were performed. Citrate synthase (CS) activity, mitochondrial DNA (mtDNA) and IMCL content were assessed in skeletal muscle samples. Both groups were comparable in anthropometric and BIA parameters, physical activity and protein-energy intake. Vegans had significantly higher glucose disposal (M-value, vegans 8.11±1.51 vs controls 6.31±1.57 mg/kg/min, 95% confidence interval: 0.402 to 3.212, P=0.014), slightly lower IMCL content (vegans 13.91 (7.8 to 44.0) vs controls 17.36 (12.4 to 78.5) mg/g of muscle, 95% confidence interval: -7.594 to 24.550, P=0.193) and slightly higher relative muscle mtDNA amount (vegans 1.36±0.31 vs controls 1.13±0.36, 95% confidence interval:-0.078 to 0.537, P=0.135). No significant differences were found in CS activity (vegans 18.43±5.05 vs controls 18.16±5.41 μmol/g/min, 95% confidence interval: -4.503 to 5.050, P=0.906). Vegans have a higher IS, but comparable mitochondrial density and IMCL content with omnivores. This suggests that a decrease in whole-body glucose disposal may precede muscle lipid accumulation and mitochondrial dysfunction in IR development.

  2. Higher engineering mathematics

    CERN Document Server

    John Bird

    2014-01-01

    A practical introduction to the core mathematics principles required at higher engineering levelJohn Bird's approach to mathematics, based on numerous worked examples and interactive problems, is ideal for vocational students that require an advanced textbook.Theory is kept to a minimum, with the emphasis firmly placed on problem-solving skills, making this a thoroughly practical introduction to the advanced mathematics engineering that students need to master. The extensive and thorough topic coverage makes this an ideal text for upper level vocational courses. Now in

  3. Measuring Intermediate-Mass Black-Hole Binaries with Advanced Gravitational Wave Detectors.

    Science.gov (United States)

    Veitch, John; Pürrer, Michael; Mandel, Ilya

    2015-10-02

    We perform a systematic study to explore the accuracy with which the parameters of intermediate-mass black-hole binary systems can be measured from their gravitational wave (GW) signatures using second-generation GW detectors. We make use of the most recent reduced-order models containing inspiral, merger, and ringdown signals of aligned-spin effective-one-body waveforms to significantly speed up the calculations. We explore the phenomenology of the measurement accuracies for binaries with total masses between 50M(⊙) and 500M(⊙) and mass ratios between 0.1 and 1. We find that (i) at total masses below ∼200M(⊙), where the signal-to-noise ratio is dominated by the inspiral portion of the signal, the chirp mass parameter can be accurately measured; (ii) at higher masses, the information content is dominated by the ringdown, and total mass is measured more accurately; (iii) the mass of the lower-mass companion is poorly estimated, especially at high total mass and more extreme mass ratios; and (iv) spin cannot be accurately measured for our injection set with nonspinning components. Most importantly, we find that for binaries with nonspinning components at all values of the mass ratio in the considered range and at a network signal-to-noise ratio of 15, analyzed with spin-aligned templates, the presence of an intermediate-mass black hole with mass >100M(⊙) can be confirmed with 95% confidence in any binary that includes a component with a mass of 130M(⊙) or greater.

  4. Towards higher intensities

    CERN Multimedia

    CERN Bulletin

    2010-01-01

    Over the past 2 weeks, commissioning of the machine protection system has advanced significantly, opening up the possibility of higher intensity collisions at 3.5 TeV. The intensity has been increased from 2 bunches of 1010 protons to 6 bunches of 2x1010 protons. Luminosities of 6x1028 cm-2s-1 have been achieved at the start of fills, a factor of 60 higher than those provided for the first collisions on 30 March.   The recent increase in LHC luminosity as recorded by the experiments. (Graph courtesy of the experiments and M. Ferro-Luzzi) To increase the luminosity further, the commissioning crews are now trying to push up the intensity of the individual proton bunches. After the successful injection of nominal intensity bunches containing 1.1x1011 protons, collisions were subsequently achieved at 450 GeV with these intensities. However, half-way through the first ramping of these nominal intensity bunches to 3.5 TeV on 15 May, a beam instability was observed, leading to partial beam loss...

  5. Higher regulators, algebraic

    CERN Document Server

    Bloch, Spencer J

    2000-01-01

    This book is the long-awaited publication of the famous Irvine lectures. Delivered in 1978 at the University of California at Irvine, these lectures turned out to be an entry point to several intimately-connected new branches of arithmetic algebraic geometry, such as regulators and special values of L-functions of algebraic varieties, explicit formulas for them in terms of polylogarithms, the theory of algebraic cycles, and eventually the general theory of mixed motives which unifies and underlies all of the above (and much more). In the 20 years since, the importance of Bloch's lectures has not diminished. A lucky group of people working in the above areas had the good fortune to possess a copy of old typewritten notes of these lectures. Now everyone can have their own copy of this classic work.

  6. Teaching at higher levels

    Science.gov (United States)

    1998-11-01

    Undergraduate physics programmes for the 21st century were under discussion at a recent event held in Arlington, USA, open to two or three members of the physics faculties of universities from across the whole country. The conference was organized by the American Association of Physics Teachers with co-sponsorship from the American Institute of Physics, the American Physical Society and Project Kaleidoscope. Among the various aims were to learn about physics departments that have successfully revitalized their undergraduate physics programmes with innovative introductory physics courses and multi-track majors programmes. Engineers and life scientists were to be asked directly how physics programmes can better serve their students, and business leaders would be speaking on how physics departments can help to prepare their students for the diverse careers that they will eventually follow. It was planned to highlight ways that departments could fulfil their responsibilities towards trainee teachers, to identify the resources needed for revitalizing a department's programme, and to develop guidelines and recommendations for a funding programme to support collaborative efforts among physics departments for carrying out the enhancements required. More details about the conference can be found on the AAPT website (see http://www.aapt.org/programs/rupc.html). Meanwhile the UK's Higher Education Funding Council has proposed a two-pronged approach to the promotion of high quality teaching and learning, as well as widening participation in higher education from 1999-2000. A total of £60m should be available to support these initiatives by the year 2001-2002. As part of this scheme the Council will invite bids from institutions to support individual academics in enhancing learning and teaching, as well as in recognition of individual excellence. As with research grants, such awards would enable staff to pursue activities such as the development of teaching materials

  7. The neutron star mass distribution

    Energy Technology Data Exchange (ETDEWEB)

    Kiziltan, Bülent [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Kottas, Athanasios; De Yoreo, Maria [Department of Applied Mathematics and Statistics, University of California, Santa Cruz, CA 95064 (United States); Thorsett, Stephen E., E-mail: bkiziltan@cfa.harvard.edu [Department of Astronomy and Astrophysics, University of California and UCO/Lick Observatory, Santa Cruz, CA 95064 (United States)

    2013-11-20

    In recent years, the number of pulsars with secure mass measurements has increased to a level that allows us to probe the underlying neutron star (NS) mass distribution in detail. We critically review the radio pulsar mass measurements. For the first time, we are able to analyze a sizable population of NSs with a flexible modeling approach that can effectively accommodate a skewed underlying distribution and asymmetric measurement errors. We find that NSs that have evolved through different evolutionary paths reflect distinctive signatures through dissimilar distribution peak and mass cutoff values. NSs in double NS and NS-white dwarf (WD) systems show consistent respective peaks at 1.33 M {sub ☉} and 1.55 M {sub ☉}, suggesting significant mass accretion (Δm ≈ 0.22 M {sub ☉}) has occurred during the spin-up phase. The width of the mass distribution implied by double NS systems is indicative of a tight initial mass function while the inferred mass range is significantly wider for NSs that have gone through recycling. We find a mass cutoff at ∼2.1 M {sub ☉} for NSs with WD companions, which establishes a firm lower bound for the maximum NS mass. This rules out the majority of strange quark and soft equation of state models as viable configurations for NS matter. The lack of truncation close to the maximum mass cutoff along with the skewed nature of the inferred mass distribution both enforce the suggestion that the 2.1 M {sub ☉} limit is set by evolutionary constraints rather than nuclear physics or general relativity, and the existence of rare supermassive NSs is possible.

  8. Higher Order Mode Fibers

    DEFF Research Database (Denmark)

    Israelsen, Stine Møller

    This PhD thesis considers higher order modes (HOMs) in optical fibers. That includes their excitation and characteristics. Within the last decades, HOMs have been applied both for space multiplexing in optical communications, group velocity dispersion management and sensing among others......-radial polarization as opposed to the linear polarization of the LP0X modes. The effect is investigated numerically in a double cladding fiber with an outer aircladding using a full vectorial modesolver. Experimentally, the bowtie modes are excited using a long period grating and their free space characteristics...... and polarization state are investigated. For this fiber, the onset of the bowtie effect is shown numerically to be LP011. The characteristics usually associated with Bessel-likes modes such as long diffraction free length and selfhealing are shown to be conserved despite the lack of azimuthal symmetry...

  9. Spiky higher genus strings

    International Nuclear Information System (INIS)

    Ambjoern, J.; Bellini, A.; Johnston, D.

    1990-10-01

    It is clear from both the non-perturbative and perturbative approaches to two-dimensional quantum gravity that a new strong coupling regime is setting in at d=1, independent of the genus of the worldsheet being considered. It has been suggested that a Kosterlitz-Thouless (KT) phase transition in the Liouville theory is the cause of this behaviour. However, it has recently been pointed out that the XY model, which displays a KT transition on the plane and the sphere, is always in the strong coupling, disordered phase on a surface of constant negative curvature. A higher genus worldsheet can be represented as a fundamental region on just such a surface, which might seem to suggest that the KT picture predicts a strong coupling region for arbitrary d, contradicting the known results. We resolve the apparent paradox. (orig.)

  10. Gravitating multidefects from higher dimensions

    CERN Document Server

    Giovannini, Massimo

    2007-01-01

    Warped configurations admitting pairs of gravitating defects are analyzed. After devising a general method for the construction of multidefects, specific examples are presented in the case of higher-dimensional Einstein-Hilbert gravity. The obtained profiles describe diverse physical situations such as (topological) kink-antikink systems, pairs of non-topological solitons and bound configurations of a kink and of a non-topological soliton. In all the mentioned cases the geometry is always well behaved (all relevant curvature invariants are regular) and tends to five-dimensional anti-de Sitter space-time for large asymptotic values of the bulk coordinate. Particular classes of solutions can be generalized to the framework where the gravity part of the action includes, as a correction, the Euler-Gauss-Bonnet combination. After scrutinizing the structure of the zero modes, the obtained results are compared with conventional gravitating configurations containing a single topological defect.

  11. Library assessment in higher education

    CERN Document Server

    Matthews, Joseph R

    2015-01-01

    Academic libraries are increasingly being asked to demonstrate their value as one of many units on campus, but determining the outcomes of an academic library within the context of its collegiate setting is challenging. This book explains and clarifies the practice of assessment in academic institutions, enabling library managers to better understand and explain the impact of the library on student learning outcomes, teaching effectiveness, and research productivity. Providing essential information for all college and university librarians, this volume discusses and summarizes the outcomes of research that has been conducted to investigate assessment within the context of higher education. This updated second edition incorporates additional research, examines new trends, and covers groundbreaking advances in digital assessment tools as well as the changes in the amount and forms of data utilized in the assessment process. The chapters address assessment from a campus setting and present data that demonstrate...

  12. Higher twist contributions to the structure functions Fp2(x,Q2) and Fd2(x,Q2) at large x at higher orders

    International Nuclear Information System (INIS)

    Bluemlein, J.; Boettcher, H.

    2008-02-01

    The higher twist contributions to the deeply inelastic structure functions F p 2 (x,Q 2 ) and F d 2 (x,Q 2 ) for larger values of the Bjorken variable x are extracted extrapolating the twist-2 contributions measured in the large W 2 region to the region 4 GeV 2 ≤W 2 ≤12.5 GeV 2 applying target mass corrections. We compare the results for the NLO, NNLO and N 3 LO analyzes and include also the large x at N 4 LO to the Wilson coefficients. A gradual lowering of the higher twist contributions going from NLO to N 4 LO is observed, which stresses the importance of higher order corrections. (orig.)

  13. A flavor symmetry model for bilarge leptonic mixing and the lepton masses

    Science.gov (United States)

    Ohlsson, Tommy; Seidl, Gerhart

    2002-11-01

    We present a model for leptonic mixing and the lepton masses based on flavor symmetries and higher-dimensional mass operators. The model predicts bilarge leptonic mixing (i.e., the mixing angles θ12 and θ23 are large and the mixing angle θ13 is small) and an inverted hierarchical neutrino mass spectrum. Furthermore, it approximately yields the experimental hierarchical mass spectrum of the charged leptons. The obtained values for the leptonic mixing parameters and the neutrino mass squared differences are all in agreement with atmospheric neutrino data, the Mikheyev-Smirnov-Wolfenstein large mixing angle solution of the solar neutrino problem, and consistent with the upper bound on the reactor mixing angle. Thus, we have a large, but not close to maximal, solar mixing angle θ12, a nearly maximal atmospheric mixing angle θ23, and a small reactor mixing angle θ13. In addition, the model predicts θ 12≃ {π}/{4}-θ 13.

  14. Higgs boson mass bounds in the presence of a heavy fourth quark family

    Energy Technology Data Exchange (ETDEWEB)

    Bulava, John [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Gerhold, Philipp; Kallarackal, Jim; Nagy, Attila [Humboldt-Universitaet, Berlin (Germany). Inst. fuer Physik; Jansen, Karl [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC

    2013-01-15

    We present Higgs boson mass bounds in a lattice regularization allowing thus for non-perturbative investigations. In particular, we employ a lattice modified chiral invariant Higgs-Yukawa model using the overlap operator. We show results for the upper and lower Higgs boson mass bounds in the presence of a heavy mass-degenerate quark doublet with masses ranging up to 700 GeV. We perform infinite volume extrapolations in most cases, and examine several values of the lattice cutoff. Furthermore, we argue that the lower Higgs boson mass bound is stable with respect to the addition of higher dimensional operators to the scalar field potential. Our results have severe consequences for the phenomenology of a fourth generation of quarks if a light Higgs boson is discovered at the LHC.

  15. Higgs boson mass bounds in the presence of a heavy fourth quark family

    CERN Document Server

    Bulava, John; Nagy, Attila; Kallarackal, Jim; Jansen, Karl

    2012-01-01

    We present Higgs boson mass bounds in a lattice regularization allowing thus for non-perturbative investigations. In particular, we employ a lattice modified chiral invariant Higgs-Yukawa model using the overlap operator. We show results for the upper and lower Higgs boson mass bounds in the presence of a heavy mass-degenerate quark doublet with masses ranging up to 700 GeV. We perform infinite volume extrapolations in most cases, and examine several values of the lattice cutoff. Furthermore, we argue that the lower Higgs boson mass bound is stable with respect to the addition of higher dimensional operators to the scalar field potential. Our results have severe consequences for the phenomenology of a fourth generation of quarks if a light Higgs boson is discovered at the LHC.

  16. Projects as value constellations

    DEFF Research Database (Denmark)

    Laursen, Markus

    Creating value has been outlined as very central to projects applying the organizational perspective to projects. It has been suggested that value is created in value constellations or project networks, where actors work together to create value. However, research on the value creation process...... in value constellations is scarce, and through an exploratory study of two project networks in a cultural setting we investigate how value is created in value constellations. We outline how each project may be a distinct type of value constellation, one project creates value for the partners of the network...... as a consortium, and the project creates value primarily for others as a facilitator....

  17. Value-based pricing

    OpenAIRE

    Netseva-Porcheva Tatyana

    2010-01-01

    The main aim of the paper is to present the value-based pricing. Therefore, the comparison between two approaches of pricing is made - cost-based pricing and value-based pricing. The 'Price sensitively meter' is presented. The other topic of the paper is the perceived value - meaning of the perceived value, the components of perceived value, the determination of perceived value and the increasing of perceived value. In addition, the best company strategies in matrix 'value-cost' are outlined. .

  18. Halo Profiles and the Concentration–Mass Relation for a ΛCDM Universe

    Science.gov (United States)

    Child, Hillary L.; Habib, Salman; Heitmann, Katrin; Frontiere, Nicholas; Finkel, Hal; Pope, Adrian; Morozov, Vitali

    2018-05-01

    Profiles of dark matter-dominated halos at the group and cluster scales play an important role in modern cosmology. Using results from two very large cosmological N-body simulations, which increase the available volume at their mass resolution by roughly two orders of magnitude, we robustly determine the halo concentration–mass (c‑M) relation over a wide range of masses, employing multiple methods of concentration measurement. We characterize individual halo profiles, as well as stacked profiles, relevant for galaxy–galaxy lensing and next-generation cluster surveys; the redshift range covered is 0 ≤ z ≤ 4, with a minimum halo mass of M 200c ∼ 2 × 1011 M ⊙. Despite the complexity of a proper description of a halo (environmental effects, merger history, nonsphericity, relaxation state), when the mass is scaled by the nonlinear mass scale M ⋆(z), we find that a simple non-power-law form for the c–M/M ⋆ relation provides an excellent description of our simulation results across eight decades in M/M ⋆ and for 0 ≤ z ≤ 4. Over the mass range covered, the c–M relation has two asymptotic forms: an approximate power law below a mass threshold M/M ⋆ ∼ 500–1000, transitioning to a constant value, c 0 ∼ 3 at higher masses. The relaxed halo fraction decreases with mass, transitioning to a constant value of ∼0.5 above the same mass threshold. We compare Navarro–Frenk–White (NFW) and Einasto fits to stacked profiles in narrow mass bins at different redshifts; as expected, the Einasto profile provides a better description of the simulation results. At cluster scales at low redshift, however, both NFW and Einasto profiles are in very good agreement with the simulation results, consistent with recent weak lensing observations.

  19. Learning higher mathematics

    CERN Document Server

    Pontrjagin, Lev Semenovič

    1984-01-01

    Lev Semenovic Pontrjagin (1908) is one of the outstanding figures in 20th century mathematics. In a long career he has made fundamental con­ tributions to many branches of mathematics, both pure and applied. He has received every honor that a grateful government can bestow. Though in no way constrained to do so, he has through the years taught mathematics courses at Moscow State University. In the year 1975 he set himself the task of writing a series of books on secondary school and beginning university mathematics. In his own words, "I wished to set forth the foundations of higher mathematics in a form that would have been accessible to myself as a lad, but making use of all my experience as a scientist and a teacher, ac­ cumulated over many years. " The present volume is a translation of the first two out of four moderately sized volumes on this theme planned by Pro­ fessor Pontrjagin. The book begins at the beginning of modern mathematics, analytic ge­ ometry in the plane and 3-dimensional space. Refin...

  20. Access to Higher Education in China: Differences in Opportunity

    Science.gov (United States)

    Wang, Houxiong

    2011-01-01

    Access to higher education in China has opened up significantly in the move towards a mass higher education system. However, aggregate growth does not necessarily imply fair or reasonable distribution of opportunity. In fact, the expansion of higher education has a rather more complex influence on opportunity when admissions statistics are viewed…

  1. CERN: Higher energies at LEP

    International Nuclear Information System (INIS)

    Anon.

    1995-01-01

    This year will be the last that CERN's 27-kilometre LEP electron-positron collider will run routinely at around 45 GeV per beam. In the run, scheduled to begin in May, the four big experiments will top up their harvest so far of over 12 million Z particles for a final polishing of precision Z data. Behind the scenes, LEP is being prepared for higher energy running and a new phase of physics. After a brief technical stop in October, the aim is for a test run of up to 70 GeV per beam before the end of the year. Higher energy demands more radiofrequency power, which will be supplied by superconducting cavities. With this goal in mind, a programme of development work began at CERN over ten years ago, when LEP was still on the drawing board. Initially this effort focused on cavities made from sheet niobium, but later switched to copper covered by a sputtered niobium film, which gives better thermal and r.f. performance (September 1990, page 24). The first industrially-manufactured four-cavity niobium coated module, complete with its cryostat and r.f plumbing, was installed in LEP in 1993. Although it quickly achieved its nominal accelerating gradient of 6 MV/m, its reliability was affected by unforeseen problems in the associated power couplers. This delayed the installation schedule, but after a crash programme of design and modification of the power couplers, together with improvements in actual cavity design and manufacture, module supply and testing has now attained a satisfactory rhythm. Two modules installed in LEP amassed between them over 50 days of continuous running in 1994, and confidence is now high that the emphasis can shift towards integrating the cavities into LEP, rather than running the cavities themselves. During LEP's 1994-5 winter shutdown, modules are being installed at Points 2 and 6. Later, additional cavities will be installed in Points 2, 6 and 8 prior to embarking on the higher energy test run at the end of the year. After

  2. Indigenous environmental values as human values

    Directory of Open Access Journals (Sweden)

    Monica Gratani

    2016-12-01

    Full Text Available The claim that in natural resource management (NRM a change from anthropocentric values and ethics to eco-centric ones is necessary to achieve sustainability leads to the search for eco-centric models of relationship with the environment. Indigenous cultures can provide such models; hence, there is the need for multicultural societies to further include their values in NRM. In this article, we investigate the environmental values placed on a freshwater environment of the Wet Tropics by a community of indigenous Australians. We discuss their environmental values as human values, and so as beliefs that guide communities’ understanding of how the natural world should be viewed and treated by humans. This perspective represents a step forward in our understanding of indigenous environmental values, and a way to overcome the paradigm of indigenous values as valued biophysical attributes of the environment or processes happening in landscapes. Our results show that the participant community holds biospheric values. Restoring these values in the NRM of the Wet Tropics could contribute to sustainability and environmental justice in the area.

  3. Mutation breeding for nutritional value in wheat

    International Nuclear Information System (INIS)

    Barriga, P.; Fuentes, R.; Manquian, N.; Mansilla, R.

    1984-01-01

    In 1981 two batches of 100,000 seeds of the spring wheat cultivars Austral and Huenufen were irradiated with gamma rays at 10 and 25 Krad doses. The source of radiation was 60 Co, from the Comision Chilena de Energia Nuclear. Objectives of this irradiation program were to develop wheat cultivars well adapted to the Lakes Region of Chile (latitude south 39 to 40 0 ), whith higher content of protein and lysine and good yield. Generation M 1 was sown densily under field conditions and harvested by mass selection. Plant selection was set up in generation M 2 onwards. Selected mutants for protein content (DBC values) in generations M 2 (1982-83) and M 3 (1983-84) showed ranges from 18 to 22%. These contents were higher than in the controls. As regards lysine content of the proteins, the number of selected was low, however mutants with maximum lysine content overshot 4%. In M 4 generation, the better mutants, with adequate number of controls, will be analyzed in the crop season 1984-85, in preliminary trials of production. The technique of horizontal polyacrylamide gel electrophoresis as an alternative technique to the identification and certification of mutants with high content of protein is examined. (Author) [pt

  4. Respiratory mass spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Mostert, J.W. (Pretoria Univ. (South Africa). Dept. of Anesthesiology)

    1983-06-01

    The high degree of technical perfection of the respiratory mass spectrometer has rendered the instrument feasible for routine monitoring of anesthetized patients. It is proposed that the difference between inspired and expired oxygen tension in mm Hg be equated with whole body oxygen consumption in ml/min/M/sup 2/ body-surface area at STPD, by the expedient of multiplying tension-differences by a factor of 2. Years of experience have confirmed the value of promptly recognizing sudden drops in this l/E tension difference below 50 mm Hg indicative of metabolic injury from hypovolemia or respiratory depression. Rises in l/E tension-differences were associated with shivering as well as voluntary muscle activity. Tension differences of less than 25 mm Hg (equated with a whole-body O/sub 2/ consumption of less than 50 ml O/sub 2//min/M/sup 2/) occurred in a patient in the sitting position for posterior fossa exploration without acidosis, hypoxia or hypotension for several hours prior to irreversible cardiac arrest. The value of clinical monitoring by mass spectrometry is especially impressive in open-heart surgery.

  5. The respiratory mass spectrometer

    International Nuclear Information System (INIS)

    Mostert, J.W.

    1983-01-01

    The high degree of technical perfection of the respiratory mass spectrometer has rendered the instrument feasible for routine monitoring of anesthetized patients. It is proposed that the difference between inspired and expired oxygen tension in mm Hg be equated with whole body oxygen consumption in ml/min/M 2 body-surface area at STPD, by the expedient of multiplying tension-differences by a factor of 2. Years of experience have confirmed the value of promptly recognizing sudden drops in this l/E tension difference below 50 mm Hg indicative of metabolic injury from hypovolemia or respiratory depression. Rises in l/E tension-differences were associated with shivering as well as voluntary muscle activity. Tension differences of less than 25 mm Hg (equated with a whole-body O 2 consumption of less than 50 ml O 2 /min/M 2 ) occurred in a patient in the sitting position for posterior fossa exploration without acidosis, hypoxia or hypotension for several hours prior to irreversible cardiac arrest. The value of clinical monitoring by mass spectrometry is especially impressive in open-heart surgery

  6. Diagnostic Accuracy of Dynamic Contrast Enhanced Magnetic Resonance Imaging in Characterizing Lung Masses

    Science.gov (United States)

    Inan, Nagihan; Arslan, Arzu; Donmez, Muhammed; Sarisoy, Hasan Tahsin

    2016-01-01

    Background Imaging plays a critical role not only in the detection, but also in the characterization of lung masses as benign or malignant. Objectives To determine the diagnostic accuracy of dynamic magnetic resonance imaging (MRI) in the differential diagnosis of benign and malignant lung masses. Patients and Methods Ninety-four masses were included in this prospective study. Five dynamic series of T1-weighted spoiled gradient echo (FFE) images were obtained, followed by a T1-weighted FFE sequence in the late phase (5th minutes). Contrast enhancement patterns in the early (25th second) and late (5th minute) phase images were evaluated. For the quantitative evaluation, signal intensity (SI)-time curves were obtained and the maximum relative enhancement, wash-in rate, and time-to-peak enhancement of masses in both groups were calculated. Results The early phase contrast enhancement patterns were homogeneous in 78.2% of the benign masses, while heterogeneous in 74.4% of the malignant tumors. On the late phase images, 70.8% of the benign masses showed homogeneous enhancement, while most of the malignant masses showed heterogeneous enhancement (82.4%). During the first pass, the maximum relative enhancement and wash-in rate values of malignant masses were significantly higher than those of the benign masses (P = 0.03 and 0.04, respectively). The cutoff value at 15% yielded a sensitivity of 85.4%, specificity of 61.2%, and positive predictive value of 68.7% for the maximum relative enhancement. Conclusion Contrast enhancement patterns and SI-time curve analysis of MRI are helpful in the differential diagnosis of benign and malignant lung masses. PMID:27703654

  7. Higher Efficiency HVAC Motors

    Energy Technology Data Exchange (ETDEWEB)

    Flynn, Charles Joseph [QM Power, Inc., Kansas City, MO (United States)

    2018-02-13

    failure prone capacitors from the power stage. Q-Sync’s simpler electronics also result in higher efficiency because it eliminates the power required by the PCB to perform the obviated power conversions and PWM processes after line synchronous operating speed is reached in the first 5 seconds of operation, after which the PWM circuits drop out and a much less energy intensive “pass through” circuit takes over, allowing the grid-supplied AC power to sustain the motor’s ongoing operation.

  8. Value and Pricing of MOOCs

    Science.gov (United States)

    Baker, Rose M.; Passmore, David L.

    2016-01-01

    Reviewed in this article is the potential for Massive Open Online Courses (MOOCs) to transform higher education delivery, accessibility, and costs. Next, five major value propositions for MOOCs are considered (headhunting, certification, face-to-face learning, personalized learning, integration with services external to the MOOC, marketing). Then,…

  9. Systems of neutrinos with mass

    International Nuclear Information System (INIS)

    Groot, S.R. de

    1984-01-01

    From the formalism of relativistic kinetic theory and the weak interaction Lagrangian the volume viscosity of a massive neutrino system is derived. Its value is calculated as a function of the neutrino mass and the temperature. Its role in the way of expanding or contraction of neutrino clouds in the universe is discussed. (Author) [pt

  10. Maslow and Values Education

    Science.gov (United States)

    Farmer, Rodney

    1978-01-01

    Identifies major value bases which have been used to teach values in the classroom and outlines a values education program which stresses teaching about values without indoctrination. Based upon the hierarchy of human needs developed by psychologist Abraham Maslow, the program is based upon universal values, basic human needs, and recognition of…

  11. Center of mass detection via an active pixel sensor

    Science.gov (United States)

    Yadid-Pecht, Orly (Inventor); Minch, Brad (Inventor); Pain, Bedabrara (Inventor); Fossum, Eric (Inventor)

    2006-01-01

    An imaging system for identifying the location of the center of mass (COM) in an image. In one aspect, an imaging system includes a plurality of photosensitive elements arranged in a matrix. A center of mass circuit coupled to the photosensitive elements includes a resistive network and a normalization circuit including at least one bipolar transistor. The center of mass circuit identifies a center of mass location in the matrix and includes: a row circuit, where the row circuit identifies a center of mass row value in each row of the matrix and identifies a row intensity for each row; a horizontal circuit, where the horizontal circuit identifies a center of mass horizontal value; and a vertical circuit, where the vertical circuit identifies a center of mass vertical value. The horizontal and vertical center of mass values indicate the coordinates of the center of mass location for the image.

  12. Receptor theory and biological constraints on value.

    Science.gov (United States)

    Berns, Gregory S; Capra, C Monica; Noussair, Charles

    2007-05-01

    Modern economic theories of value derive from expected utility theory. Behavioral evidence points strongly toward departures from linear value weighting, which has given rise to alternative formulations that include prospect theory and rank-dependent utility theory. Many of the nonlinear forms for value assumed by these theories can be derived from the assumption that value is signaled by neurotransmitters in the brain, which obey simple laws of molecular movement. From the laws of mass action and receptor occupancy, we show how behaviorally observed forms of nonlinear value functions can arise.

  13. Variational treatment of the centre-of-mass motion

    International Nuclear Information System (INIS)

    Cornelissens, T.

    1986-01-01

    The weightfunction in Lipkin's general expression for eliminating the centre-of-mass coordinate from nuclear wavefunctions has been approximated by a gaussian function exp (-lambdaR 2 ) with one parameter lambda to be determined by a variational calculation. This variational calculation has been carried out for the ground state of 6 Li, first using a wavefunction with different oscillator parameters for the s and p nucleons, second using oscillator functions which are also axially deformed. In both cases the centre-of-mass treatment leads to a remarkable energy gain. The lowest energies are obtained for a negative value of lambda. This surprising result can be explained on the basis of a cluster model for the internal wavefunction of 6 Li : the negative value of lambda increases the separation between the alpha and deuteron cluster. As a further test for our centre-of-mass corrected internal wavefunctions we have calculated the charge formfactor of 6 Li. At low momentum transfer we obtain an excellent agreement with the experimental results. At higher momentum transfers we obtain a diffraction dip, but not yet at the right position and height. Finally we have compared our results for the ground state energy with different cluster model results in the literature. We can conclude that, even without using a generator coordinate method, our centre-of-mass corrected wavefunctions lead to equally good results as the most sophisticated cluster models

  14. Effect of minimal length uncertainty on the mass-radius relation of white dwarfs

    Science.gov (United States)

    Mathew, Arun; Nandy, Malay K.

    2018-06-01

    Generalized uncertainty relation that carries the imprint of quantum gravity introduces a minimal length scale into the description of space-time. It effectively changes the invariant measure of the phase space through a factor (1 + βp2) - 3 so that the equation of state for an electron gas undergoes a significant modification from the ideal case. It has been shown in the literature (Rashidi 2016) that the ideal Chandrasekhar limit ceases to exist when the modified equation of state due to the generalized uncertainty is taken into account. To assess the situation in a more complete fashion, we analyze in detail the mass-radius relation of Newtonian white dwarfs whose hydrostatic equilibria are governed by the equation of state of the degenerate relativistic electron gas subjected to the generalized uncertainty principle. As the constraint of minimal length imposes a severe restriction on the availability of high momentum states, it is speculated that the central Fermi momentum cannot have values arbitrarily higher than pmax ∼β - 1 / 2. When this restriction is imposed, it is found that the system approaches limiting mass values higher than the Chandrasekhar mass upon decreasing the parameter β to a value given by a legitimate upper bound. Instead, when the more realistic restriction due to inverse β-decay is considered, it is found that the mass and radius approach the values 1.4518 M⊙ and 601.18 km near the legitimate upper bound for the parameter β.

  15. On the hadron mass decomposition

    Science.gov (United States)

    Lorcé, Cédric

    2018-02-01

    We argue that the standard decompositions of the hadron mass overlook pressure effects, and hence should be interpreted with great care. Based on the semiclassical picture, we propose a new decomposition that properly accounts for these pressure effects. Because of Lorentz covariance, we stress that the hadron mass decomposition automatically comes along with a stability constraint, which we discuss for the first time. We show also that if a hadron is seen as made of quarks and gluons, one cannot decompose its mass into more than two contributions without running into trouble with the consistency of the physical interpretation. In particular, the so-called quark mass and trace anomaly contributions appear to be purely conventional. Based on the current phenomenological values, we find that in average quarks exert a repulsive force inside nucleons, balanced exactly by the gluon attractive force.

  16. On the hadron mass decomposition

    Energy Technology Data Exchange (ETDEWEB)

    Lorce, Cedric [Universite Paris-Saclay, Centre de Physique Theorique, Ecole Polytechnique, CNRS, Palaiseau (France)

    2018-02-15

    We argue that the standard decompositions of the hadron mass overlook pressure effects, and hence should be interpreted with great care. Based on the semiclassical picture, we propose a new decomposition that properly accounts for these pressure effects. Because of Lorentz covariance, we stress that the hadron mass decomposition automatically comes along with a stability constraint, which we discuss for the first time. We show also that if a hadron is seen as made of quarks and gluons, one cannot decompose its mass into more than two contributions without running into trouble with the consistency of the physical interpretation. In particular, the so-called quark mass and trace anomaly contributions appear to be purely conventional. Based on the current phenomenological values, we find that in average quarks exert a repulsive force inside nucleons, balanced exactly by the gluon attractive force. (orig.)

  17. On the quark-mass dependence of baryon ground-state masses

    International Nuclear Information System (INIS)

    Semke, Alexander

    2010-01-01

    Baryon masses of the flavour SU(3) octet and decuplet baryons are calculated in the framework of the Chiral Perturbations Theory - the effective field theory of the strong interaction. The chiral extrapolation to the higher meson (quark) masses is carried out. The comparison with the recent results on the baryon masses from lattice calculations are presented. (orig.)

  18. On the quark-mass dependence of baryon ground-state masses

    Energy Technology Data Exchange (ETDEWEB)

    Semke, Alexander

    2010-02-17

    Baryon masses of the flavour SU(3) octet and decuplet baryons are calculated in the framework of the Chiral Perturbations Theory - the effective field theory of the strong interaction. The chiral extrapolation to the higher meson (quark) masses is carried out. The comparison with the recent results on the baryon masses from lattice calculations are presented. (orig.)

  19. Influence of different sports on fat mass and lean mass in growing girls

    Directory of Open Access Journals (Sweden)

    Esther Ubago-Guisado

    2017-06-01

    Conclusion: Impact sports (football, basketball, and handball and low-impact sports (swimming provide an appropriate development of lean mass in growing girls. We can conclude that people practicing sports at early ages ensure a lower fat mass and higher lean mass compared to those who do not practice. These results may be useful as a preventive method of adult obesity.

  20. Effect of massing on larval growth rate.

    Science.gov (United States)

    Johnson, Aidan P; Wallman, James F

    2014-08-01

    Estimation of minimum postmortem interval commonly relies on predicting the age of blowfly larvae based on their size and an estimate of the temperatures to which they have been exposed throughout their development. The majority of larval growth rate data have been developed using small larval masses in order to avoid excess heat generation. The current study collected growth rate data for larvae at different mass volumes, and assessed the temperature production of these masses, for two forensically important blow fly species, Chrysomya rufifacies and Calliphora vicina. The growth rate of larvae in a small mass, exposed to the higher temperatures equivalent to those experienced by large masses, was also assessed to determine if observed differences were due to the known temperature effects of maggot masses. The results showed that temperature production increased with increasing mass volume, with temperature increases of 11 °C observed in the large Ch. rufifacies masses and increases of 5 °C in the large C. vicina masses. Similarly, the growth rate of the larvae was affected by mass size. The larvae from small masses grown at the higher temperatures experienced by large masses displayed an initial delay in growth, but then grew at a similar rate to those larvae at a constant 23 °C. Since these larvae from masses of equivalent sizes displayed similar patterns of growth rate, despite differing temperatures, and these growth rates differed from larger masses exposed to the same temperatures, it can be concluded that larval growth rate within a mass may be affected by additional factors other than temperature. Overall, this study highlights the importance of understanding the role of massing in larval development and provides initial developmental data for mass sizes of two forensically important blowfly species commonly encountered in Australian forensic casework. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.