WorldWideScience

Sample records for high-sensitivity microfluidic calorimeters

  1. Transportable high sensitivity small sample radiometric calorimeter

    International Nuclear Information System (INIS)

    Wetzel, J.R.; Biddle, R.S.; Cordova, B.S.; Sampson, T.E.; Dye, H.R.; McDow, J.G.

    1998-01-01

    A new small-sample, high-sensitivity transportable radiometric calorimeter, which can be operated in different modes, contains an electrical calibration method, and can be used to develop secondary standards, will be described in this presentation. The data taken from preliminary tests will be presented to indicate the precision and accuracy of the instrument. The calorimeter and temperature-controlled bath, at present, require only a 30-in. by 20-in. tabletop area. The calorimeter is operated from a laptop computer system using unique measurement module capable of monitoring all necessary calorimeter signals. The calorimeter can be operated in the normal calorimeter equilibration mode, as a comparison instrument, using twin chambers and an external electrical calibration method. The sample chamber is 0.75 in (1.9 cm) in diameter by 2.5 in. (6.35 cm) long. This size will accommodate most 238 Pu heat standards manufactured in the past. The power range runs from 0.001 W to <20 W. The high end is only limited by sample size

  2. CONSTRUCTION OF A DIFFERENTIAL ISOTHERMAL CALORIMETER OF HIGH SENSITIVITY AND LOW COST.

    OpenAIRE

    Trinca, RB; Perles, CE; Volpe, PLO

    2009-01-01

    CONSTRUCTION OF A DIFFERENTIAL ISOTHERMAL CALORIMETER OF HIGH SENSITIVITY AND LOW COST The high cost of sensitivity commercial calorimeters may represent an obstacle for many calorimetric research groups. This work describes (fie construction and calibration of a batch differential heat conduction calorimeter with sample cells volumes of about 400 mu L. The calorimeter was built using two small high sensibility square Peltier thermoelectric sensors and the total cost was estimated to be about...

  3. High-Sensitivity Temperature-Independent Silicon Photonic Microfluidic Biosensors

    Science.gov (United States)

    Kim, Kangbaek

    Optical biosensors that can precisely quantify the presence of specific molecular species in real time without the need for labeling have seen increased use in the drug discovery industry and molecular biology in general. Of the many possible optical biosensors, the TM mode Si biosensor is shown to be very attractive in the sensing application because of large field amplitude on the surface and cost effective CMOS VLSI fabrication. Noise is the most fundamental factor that limits the performance of sensors in development of high-sensitivity biosensors, and noise reduction techniques require precise studies and analysis. One such example stems from thermal fluctuations. Generally SOI biosensors are vulnerable to ambient temperature fluctuations because of large thermo-optic coefficient of silicon (˜2x10 -4 RIU/K), typically requiring another reference ring and readout sequence to compensate temperature induced noise. To address this problem, we designed sensors with a novel TM-mode shallow-ridge waveguide that provides both large surface amplitude for bulk and surface sensing. With proper design, this also provides large optical confinement in the aqueous cladding that renders the device athermal using the negative thermo-optic coefficient of water (~ --1x10-4RIU/K), demonstrating cancellation of thermo-optic effects for aqueous solution operation near 300K. Additional limitations resulting from mechanical actuator fluctuations, stability of tunable lasers, and large 1/f noise of lasers and sensor electronics can limit biosensor performance. Here we also present a simple harmonic feedback readout technique that obviates the need for spectrometers and tunable lasers. This feedback technique reduces the impact of 1/f noise to enable high-sensitivity, and a DSP lock-in with 256 kHz sampling rate can provide down to micros time scale monitoring for fast transitions in biomolecular concentration with potential for small volume and low cost. In this dissertation, a novel

  4. Haemocompatibility of iron oxide nanoparticles synthesized for theranostic applications: a high-sensitivity microfluidic tool

    Energy Technology Data Exchange (ETDEWEB)

    Rodrigues, Raquel O. [Polytechnic Institute of Bragança, Laboratory of Separation and Reaction Engineering-Laboratory of Catalysis and Materials (LSRE-LCM) (Portugal); Bañobre-López, Manuel; Gallo, Juan [INL-International Iberian Nanotechnology Laboratory, Advanced (Magnetic) Theranostic Nanostructures Lab (Portugal); Tavares, Pedro B. [Universidade de Trás-os-Montes e Alto Douro, CQVR-Centro de Química-Vila Real (Portugal); Silva, Adrián M. T. [Universidade do Porto, Laboratory of Separation and Reaction Engineering-Laboratory of Catalysis and Materials (LSRE-LCM), Faculdade de Engenharia (Portugal); Lima, Rui, E-mail: rl@dem.uminho.pt [MEtRiCS, University of Minho, Mechanical Engineering Department (Portugal); Gomes, Helder T. [Polytechnic Institute of Bragança, Laboratory of Separation and Reaction Engineering-Laboratory of Catalysis and Materials (LSRE-LCM) (Portugal)

    2016-07-15

    The poor heating efficiency of the most reported magnetic nanoparticles (MNPs), allied to the lack of comprehensive biocompatibility and haemodynamic studies, hampers the spread of multifunctional nanoparticles as the next generation of therapeutic bio-agents in medicine. The present work reports the synthesis and characterization, with special focus on biological/toxicological compatibility, of superparamagnetic nanoparticles with diameter around 18 nm, suitable for theranostic applications (i.e. simultaneous diagnosis and therapy of cancer). Envisioning more insights into the complex nanoparticle-red blood cells (RBCs) membrane interaction, the deformability of the human RBCs in contact with magnetic nanoparticles (MNPs) was assessed for the first time with a microfluidic extensional approach, and used as an indicator of haematological disorders in comparison with a conventional haematological test, i.e. the haemolysis analysis. Microfluidic results highlight the potential of this microfluidic tool over traditional haemolysis analysis, by detecting small increments in the rigidity of the blood cells, when traditional haemotoxicology analysis showed no significant alteration (haemolysis rates lower than 2 %). The detected rigidity has been predicted to be due to the wrapping of small MNPs by the bilayer membrane of the RBCs, which is directly related to MNPs size, shape and composition. The proposed microfluidic tool adds a new dimension into the field of nanomedicine, allowing to be applied as a high-sensitivity technique capable of bringing a better understanding of the biological impact of nanoparticles developed for clinical applications.

  5. Automated microfluidically controlled electrochemical biosensor for the rapid and highly sensitive detection of Francisella tularensis.

    Science.gov (United States)

    Dulay, Samuel B; Gransee, Rainer; Julich, Sandra; Tomaso, Herbert; O'Sullivan, Ciara K

    2014-09-15

    Tularemia is a highly infectious zoonotic disease caused by a Gram-negative coccoid rod bacterium, Francisella tularensis. Tularemia is considered as a life-threatening potential biological warfare agent due to its high virulence, transmission, mortality and simplicity of cultivation. In the work reported here, different electrochemical immunosensor formats for the detection of whole F. tularensis bacteria were developed and their performance compared. An anti-Francisella antibody (FB11) was used for the detection that recognises the lipopolysaccharide found in the outer membrane of the bacteria. In the first approach, gold-supported self-assembled monolayers of a carboxyl terminated bipodal alkanethiol were used to covalently cross-link with the FB11 antibody. In an alternative second approach F(ab) fragments of the FB11 antibody were generated and directly chemisorbed onto the gold electrode surface. The second approach resulted in an increased capture efficiency and higher sensitivity. Detection limits of 4.5 ng/mL for the lipopolysaccharide antigen and 31 bacteria/mL for the F. tularensis bacteria were achieved. Having demonstrated the functionality of the immunosensor, an electrode array was functionalised with the antibody fragment and integrated with microfluidics and housed in a tester set-up that facilitated complete automation of the assay. The only end-user intervention is sample addition, requiring less than one-minute hands-on time. The use of the automated microfluidic set-up not only required much lower reagent volumes but also the required incubation time was considerably reduced and a notable increase of 3-fold in assay sensitivity was achieved with a total assay time from sample addition to read-out of less than 20 min. Copyright © 2014 Elsevier B.V. All rights reserved.

  6. HistoFlex-a microfluidic device providing uniform flow conditions enabling highly sensitive, reproducible and quantitative in situ hybridizations

    DEFF Research Database (Denmark)

    Søe, Martin Jensen; Okkels, Fridolin; Sabourin, David

    2011-01-01

    A microfluidic device (the HistoFlex) designed to perform and monitor molecular biological assays under dynamic flow conditions on microscope slide-substrates, with special emphasis on analyzing histological tissue sections, is presented. Microscope slides were reversibly sealed onto a cast polyd...

  7. Droplet Microfluidics Platform for Highly Sensitive and Quantitative Detection of Malaria-Causing Plasmodium Parasites Based on Enzyme Activity Measurement

    DEFF Research Database (Denmark)

    Juul, Sissel; Nielsen, Christine Juul Fælled; Labouriau, Rodrigo

    2012-01-01

    detectable at the single-molecule level. Combined with a droplet microfluidics lab-on-a-chip platform, this design allowed for sensitive, specific, and quantitative detection of all human-malaria-causing Plasmodium species in single drops of unprocessed blood with a detection limit of less than one parasite....../μL. Moreover, the setup allowed for detection of Plasmodium parasites in noninvasive saliva samples from infected patients. During recent years malaria transmission has declined worldwide, and with this the number of patients with low-parasite density has increased. Consequently, the need for accurate...

  8. Construção de um calorímetro isotérmico diferencial de alta sensibilidade e baixo custo Construction of a differential isothermal calorimeter of high sensitivity and low cost

    Directory of Open Access Journals (Sweden)

    Rafael Bergamo Trinca

    2009-01-01

    Full Text Available The high cost of sensitivity commercial calorimeters may represent an obstacle for many calorimetric research groups. This work describes the construction and calibration of a batch differential heat conduction calorimeter with sample cells volumes of about 400 μL. The calorimeter was built using two small high sensibility square Peltier thermoelectric sensors and the total cost was estimated to be about US$ 500. The calorimeter was used to study the excess enthalpy of solution of binary mixtures of liquids, as a function of composition, for the following binary systems of solvents: water + 1,4-dioxane or + dimethylsulfoxide at 298,2 ± 0,5 K.

  9. High-Sensitivity Spectrophotometry.

    Science.gov (United States)

    Harris, T. D.

    1982-01-01

    Selected high-sensitivity spectrophotometric methods are examined, and comparisons are made of their relative strengths and weaknesses and the circumstances for which each can best be applied. Methods include long path cells, noise reduction, laser intracavity absorption, thermocouple calorimetry, photoacoustic methods, and thermo-optical methods.…

  10. Highly Sensitive Optical Receivers

    CERN Document Server

    Schneider, Kerstin

    2006-01-01

    Highly Sensitive Optical Receivers primarily treats the circuit design of optical receivers with external photodiodes. Continuous-mode and burst-mode receivers are compared. The monograph first summarizes the basics of III/V photodetectors, transistor and noise models, bit-error rate, sensitivity and analog circuit design, thus enabling readers to understand the circuits described in the main part of the book. In order to cover the topic comprehensively, detailed descriptions of receivers for optical data communication in general and, in particular, optical burst-mode receivers in deep-sub-µm CMOS are presented. Numerous detailed and elaborate illustrations facilitate better understanding.

  11. Plutonium assay calorimeters

    International Nuclear Information System (INIS)

    Perry, R.B.

    1978-01-01

    Three calorimeters were developed for the IAEA: a small-sample portable calorimeter, a bulk calorimeter for up to 2 kg Pu in cans and capable of measuring up to 25 watts, and a calorimeter for 4-m long LWR Pu-recycle fuel roads. Design parameters and performance capability are given, and the instruments are compared with those developed for NRC

  12. Installing the ATLAS calorimeter

    CERN Multimedia

    Maximilien Brice

    2005-01-01

    The eight toroid magnets can be seen surrounding the calorimeter that is later moved into the middle of the detector. This calorimeter will measure the energies of particles produced when protons collide in the centre of the detector.

  13. OPAL detector electromagnetic calorimeter

    CERN Multimedia

    1988-01-01

    Half of the electromagnetic calorimeter of the OPAL detector is seen in this photo. This calorimeter consists of 4720 blocks of lead glass. It was used to detect and measure the energy of photons, electrons and positrons by absorbing them.

  14. Peltier ac calorimeter

    OpenAIRE

    Jung, D. H.; Moon, I. K.; Jeong, Y. H.

    2001-01-01

    A new ac calorimeter, utilizing the Peltier effect of a thermocouple junction as an ac power source, is described. This Peltier ac calorimeter allows to measure the absolute value of heat capacity of small solid samples with sub-milligrams of mass. The calorimeter can also be used as a dynamic one with a dynamic range of several decades at low frequencies.

  15. Quartz fiber calorimeter

    International Nuclear Information System (INIS)

    Akchurin, N.; Doulas, S.; Ganel, O.; Gershtein, Y.; Gavrilov, V.; Kolosov, V.; Kuleshov, S.; Litvinsev, D.; Merlo, J.-P.; Onel, Y.; Osborne, D.; Rosowsky, A.; Stolin, V.; Sulak, L.; Sullivan, J.; Ulyanov, A.; Wigmans, R.; Winn, D.

    1996-01-01

    A calorimeter with optical quartz fibers embedded into an absorber matrix was proposed for the small angle region of the CMS detector at LHC (CERN). This type of calorimeter is expected to be radiation hard and to produce extremely fast signal. Some results from beam tests of the quartz fiber calorimeter prototype are presented. (orig.)

  16. Microfluidic electronics.

    Science.gov (United States)

    Cheng, Shi; Wu, Zhigang

    2012-08-21

    Microfluidics, a field that has been well-established for several decades, has seen extensive applications in the areas of biology, chemistry, and medicine. However, it might be very hard to imagine how such soft microfluidic devices would be used in other areas, such as electronics, in which stiff, solid metals, insulators, and semiconductors have previously dominated. Very recently, things have radically changed. Taking advantage of native properties of microfluidics, advances in microfluidics-based electronics have shown great potential in numerous new appealing applications, e.g. bio-inspired devices, body-worn healthcare and medical sensing systems, and ergonomic units, in which conventional rigid, bulky electronics are facing insurmountable obstacles to fulfil the demand on comfortable user experience. Not only would the birth of microfluidic electronics contribute to both the microfluidics and electronics fields, but it may also shape the future of our daily life. Nevertheless, microfluidic electronics are still at a very early stage, and significant efforts in research and development are needed to advance this emerging field. The intention of this article is to review recent research outcomes in the field of microfluidic electronics, and address current technical challenges and issues. The outlook of future development in microfluidic electronic devices and systems, as well as new fabrication techniques, is also discussed. Moreover, the authors would like to inspire both the microfluidics and electronics communities to further exploit this newly-established field.

  17. Indirect measurement of the magnetocaloric effect using a novel differential scanning calorimeter with magnetic field

    DEFF Research Database (Denmark)

    Jeppesen, Stinus; Linderoth, Søren; Pryds, Nini

    2008-01-01

    A simple and high-sensitivity differential scanning calorimeter (DSC) unit operating under magnetic field has been built for indirect determination of the magnetocaloric effect. The principle of the measuring unit in the calorimeter is based on Peltier elements as heat flow sensors. The high...

  18. Micro Calorimeter for Batteries

    Energy Technology Data Exchange (ETDEWEB)

    Santhanagopalan, Shriram [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2017-08-01

    As battery technology forges ahead and consumer demand for safer, more affordable, high-performance batteries grows, the National Renewable Energy Laboratory (NREL) has added a patented Micro Calorimeter to its existing family of R&D 100 Award-winning Isothermal Battery Calorimeters (IBCs). The Micro Calorimeter examines the thermal signature of battery chemistries early on in the design cycle using popular coin cell and small pouch cell designs, which are simple to fabricate and study.

  19. LHCb calorimeter electronics. Photon identification. Calorimeter calibration

    International Nuclear Information System (INIS)

    Machefert, F.

    2011-01-01

    LHCb is one of the four large experiments installed on the LHC accelerator ring. The aim of the detector is to precisely measure CP violation observables and rare decays in the B meson sector. The calorimeter system of LHCb is made of four sub-systems: the scintillating pad detector, the pre-shower, the electromagnetic (ECAL) and hadronic (HCAL) calorimeters. It is essential to reconstruct B decays, to efficiently trigger on interesting events and to identify electrons and photons. After a review of the LHCb detector sub-systems, the first part of this document describes the calorimeter electronics. First, the front-end electronics in charge of measuring the ECAL and HCAL signals from the photomultipliers is presented, then the following section is an overview of the control card of the four calorimeters. The chapters three and four concern the test software of this electronics and the technological choices making it tolerant to radiations in the LHCb cavern environment. The measurements performed to ensure this tolerance are also given. The second part of this document concerns both the identification of the photons with LHCb and the calibration of the calorimeters. The photon identification method is presented and the performances given. Finally, the absolute energy calibration of the PRS and ECAL, based on the data stored in 2010 is explained. (author)

  20. PANDA electromagnetic calorimeters

    International Nuclear Information System (INIS)

    Semenov, P.A.; Kharlov, Yu.V.; Uzunian, A.V.; Chernichenko, S.K.; Derevschikov, A.A.; Davidenko, A.M.; Goncharenko, Y.M.; Kachanov, V.A.; Konstantinov, A.S.; Kormilitsin, V.A.; Matulenko, Yu.A.; Meschanin, A.P.; Melnick, Y.M.; Minaev, N.G.; Mochalov, V.V.; Morozov, D.A.; Novotny, R.W.; Ryazantsev, A.A.; Soldatov, A.P.; Soloviev, L.F.

    2009-01-01

    PANDA is a challenging experimental setup to be implemented at the high-energy storage ring (HESR) at the international facility FAIR, GSI (Germany). PANDA physics program relies heavily on the capability to measure photons with excellent energy, position and timing resolution. For this purpose PANDA proposed to employ electromagnetic calorimeters using two different technologies: compact crystal calorimeter cooled to -25 deg. C around target and lead-scintillator sandwich calorimeter with optical fibers light collection (so-called shashlyk calorimeter) in the forward region. Institute for High Energy Physics (IHEP) PANDA group reports on two types of measurements performed at IHEP, Protvino: radiation hardness of the PWO crystals at -25 deg. C and testbeam studies of the energy and position resolution of the shashlyk calorimeter prototype in the energy range up to 19 GeV.

  1. AIDA: concerted calorimeter development

    CERN Multimedia

    Felix Sefkow

    2013-01-01

    AIDA – the EU-funded project bringing together more than 80 institutes worldwide – aims at developing new detector solutions for future accelerators. Among the highlights reported at AIDA’s recent annual meeting in Frascati was the completion of an impressive calorimeter test beam programme, conducted by the CALICE collaboration over the past two years at CERN’s PS and SPS beam lines.   The CALICE tungsten calorimeter prototype under test at CERN. This cubic-metre hadron calorimeter prototype has almost 500,000 individually read-out electronics channels – more than all the calorimeters of ATLAS and CMS put together. Calorimeter development in AIDA is mainly motivated by experiments at possible future electron-positron colliders, namely ILC or CLIC. The physics requirements of such future machines demand extremely high-performance calorimetry. This is best achieved using a finely segmented system that reconstructs events using the so-called pa...

  2. Microfluidic Technologies for Synthetic Biology

    Directory of Open Access Journals (Sweden)

    Sung Kuk Lee

    2011-06-01

    Full Text Available Microfluidic technologies have shown powerful abilities for reducing cost, time, and labor, and at the same time, for increasing accuracy, throughput, and performance in the analysis of biological and biochemical samples compared with the conventional, macroscale instruments. Synthetic biology is an emerging field of biology and has drawn much attraction due to its potential to create novel, functional biological parts and systems for special purposes. Since it is believed that the development of synthetic biology can be accelerated through the use of microfluidic technology, in this review work we focus our discussion on the latest microfluidic technologies that can provide unprecedented means in synthetic biology for dynamic profiling of gene expression/regulation with high resolution, highly sensitive on-chip and off-chip detection of metabolites, and whole-cell analysis.

  3. International workshop on calorimeter simulation

    International Nuclear Information System (INIS)

    Filges, D.; Cloth, P.

    1988-10-01

    The aim of the Juelich workshop was to provide an overview of the state of calorimeter simulation and the methods used. This resulted in 29 contributions to the following topics: Code systems relevant to calorimeter simulation, vectorization and code speed-up, simulation of calorimeter experiments, special applications of calorimeter simulation. This report presents the viewgraphs of the given talks. (orig./HSI)

  4. Calorimeters for biotechnology

    International Nuclear Information System (INIS)

    Russell, Donald J.; Hansen, Lee D.

    2006-01-01

    The isothermal and temperature scanning calorimeters manufactured by Calorimetry Sciences Corporation are briefly described. Applications of calorimetry to determine thermodynamics and kinetics of reactions of interest in biotechnology are described with illustrative examples

  5. GSPEL - Calorimeter Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Testing performance claims on heat transfer componentsThe Calorimeter Lab, located in the Ground Systems Power and Energy Lab (GSPEL), is one of the largest in the...

  6. The ATLAS electromagnetic calorimeter

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    Michel Mathieu, a technician for the ATLAS collaboration, is cabling the ATLAS electromagnetic calorimeter's first end-cap, before insertion into its cryostat. Millions of wires are connected to the electromagnetic calorimeter on this end-cap that must be carefully fed out from the detector so that data can be read out. Every element on the detector will be attached to one of these wires so that a full digital map of the end-cap can be recreated.

  7. Microfabrication and Applications of Opto-Microfluidic Sensors

    Science.gov (United States)

    Zhang, Daiying; Men, Liqiu; Chen, Qiying

    2011-01-01

    A review of research activities on opto-microfluidic sensors carried out by the research groups in Canada is presented. After a brief introduction of this exciting research field, detailed discussion is focused on different techniques for the fabrication of opto-microfluidic sensors, and various applications of these devices for bioanalysis, chemical detection, and optical measurement. Our current research on femtosecond laser microfabrication of optofluidic devices is introduced and some experimental results are elaborated. The research on opto-microfluidics provides highly sensitive opto-microfluidic sensors for practical applications with significant advantages of portability, efficiency, sensitivity, versatility, and low cost. PMID:22163904

  8. Design of highly sensitive multichannel bimetallic photonic crystal fiber biosensor

    Science.gov (United States)

    Hameed, Mohamed Farhat O.; Alrayk, Yassmin K. A.; Shaalan, Abdelhamid A.; El Deeb, Walid S.; Obayya, Salah S. A.

    2016-10-01

    A design of a highly sensitive multichannel biosensor based on photonic crystal fiber is proposed and analyzed. The suggested design has a silver layer as a plasmonic material coated by a gold layer to protect silver oxidation. The reported sensor is based on detection using the quasi transverse electric (TE) and quasi transverse magnetic (TM) modes, which offers the possibility of multichannel/multianalyte sensing. The numerical results are obtained using a finite element method with perfect matched layer boundary conditions. The sensor geometrical parameters are optimized to achieve high sensitivity for the two polarized modes. High-refractive index sensitivity of about 4750 nm/RIU (refractive index unit) and 4300 nm/RIU with corresponding resolutions of 2.1×10-5 RIU, and 2.33×10-5 RIU can be obtained according to the quasi TM and quasi TE modes of the proposed sensor, respectively. Further, the reported design can be used as a self-calibration biosensor within an unknown analyte refractive index ranging from 1.33 to 1.35 with high linearity and high accuracy. Moreover, the suggested biosensor has advantages in terms of compactness and better integration of microfluidics setup, waveguide, and metallic layers into a single structure.

  9. Proportional wire calorimeters at ISABELLE

    International Nuclear Information System (INIS)

    Matthews, J.A.J.

    1979-01-01

    Gas calorimeters have recently increased in popularity because they provide a simple method of achieving a high degree of calorimeter segmentation with only a modest loss in energy resolution compared with liquid argon or scintillator calorimeters. High radiation levels at ISABELLE will result in gas calorimeter lifetimes similar to those of MWPCs, although the intermediate speed of these devices may cause some resolution degradation due to signal pileup. Schemes for calibration and monitoring gas calorimeters in situ must be evolved and will presumably utilize a combination of pulsers, imbedded 55 Fe sources, etc. Most of the recent development work on gas calorimeters has been centered on electromagnetic (em) calorimetry for large detectors at CESR and PEP. Data on the performance of gas calorimeters are given and compared with the liquid argon results of Hitlin et al. The hadronic gas calorimeter results of Anderson et al. are shown along with typical energy resolution results from various scintillator and liquid argon steel calorimeters

  10. Optical calorimetry in microfluidic droplets.

    Science.gov (United States)

    Chamoun, Jacob; Pattekar, Ashish; Afshinmanesh, Farzaneh; Martini, Joerg; Recht, Michael I

    2018-05-29

    A novel microfluidic calorimeter that measures the enthalpy change of reactions occurring in 100 μm diameter aqueous droplets in fluoropolymer oil has been developed. The aqueous reactants flow into a microfluidic droplet generation chip in separate fluidic channels, limiting contact between the streams until immediately before they form the droplet. The diffusion-driven mixing of reactants is predominantly restricted to within the droplet. The temperature change in droplets due to the heat of reaction is measured optically by recording the reflectance spectra of encapsulated thermochromic liquid crystals (TLC) that are added to one of the reactant streams. As the droplets travel through the channel, the spectral characteristics of the TLC represent the internal temperature, allowing optical measurement with a precision of ≈6 mK. The microfluidic chip and all fluids are temperature controlled, and the reaction heat within droplets raises their temperature until thermal diffusion dissipates the heat into the surrounding oil and chip walls. Position resolved optical temperature measurement of the droplets allows calculation of the heat of reaction by analyzing the droplet temperature profile over time. Channel dimensions, droplet generation rate, droplet size, reactant stream flows and oil flow rate are carefully balanced to provide rapid diffusional mixing of reactants compared to thermal diffusion, while avoiding thermal "quenching" due to contact between the droplets and the chip walls. Compared to conventional microcalorimetry, which has been used in this work to provide reference measurements, this new continuous flow droplet calorimeter has the potential to perform titrations ≈1000-fold faster while using ≈400-fold less reactants per titration.

  11. Magnetically Coupled Calorimeters

    Science.gov (United States)

    Bandler, Simon

    2011-01-01

    Calorimeters that utilize the temperature sensitivity of magnetism have been under development for over 20 years. They have targeted a variety of different applications that require very high resolution spectroscopy. I will describe the properties of this sensor technology that distinguish it from other low temperature detectors and emphasize the types of application to which they appear best suited. I will review what has been learned so far about the best materials, geometries, and read-out amplifiers and our understanding of the measured performance and theoretical limits. I will introduce some of the applications where magnetic calorimeters are being used and also where they are in development for future experiments. So far, most magnetic calorimeter research has concentrated on the use of paramagnets to provide temperature sensitivity; recent studies have also focused on magnetically coupled calorimeters that utilize the diamagnetic response of superconductors. I will present some of the highlights of this research, and contrast the properties of the two magnetically coupled calorimeter types.

  12. Self-contained microfluidic systems: a review.

    Science.gov (United States)

    Boyd-Moss, Mitchell; Baratchi, Sara; Di Venere, Martina; Khoshmanesh, Khashayar

    2016-08-16

    Microfluidic systems enable rapid diagnosis, screening and monitoring of diseases and health conditions using small amounts of biological samples and reagents. Despite these remarkable features, conventional microfluidic systems rely on bulky expensive external equipment, which hinders their utility as powerful analysis tools outside of research laboratories. 'Self-contained' microfluidic systems, which contain all necessary components to facilitate a complete assay, have been developed to address this limitation. In this review, we provide an in-depth overview of self-contained microfluidic systems. We categorise these systems based on their operating mechanisms into three major groups: passive, hand-powered and active. Several examples are provided to discuss the structure, capabilities and shortcomings of each group. In particular, we discuss the self-contained microfluidic systems enabled by active mechanisms, due to their unique capability for running multi-step and highly controllable diagnostic assays. Integration of self-contained microfluidic systems with the image acquisition and processing capabilities of smartphones, especially those equipped with accessory optical components, enables highly sensitive and quantitative assays, which are discussed. Finally, the future trends and possible solutions to expand the versatility of self-contained, stand-alone microfluidic platforms are outlined.

  13. Theoretical microfluidics

    DEFF Research Database (Denmark)

    Bruus, Henrik

    Microfluidics is a young and rapidly expanding scientific discipline, which deals with fluids and solutions in miniaturized systems, the so-called lab-on-a-chip systems. It has applications in chemical engineering, pharmaceutics, biotechnology and medicine. As the lab-on-a-chip systems grow...

  14. The ATLAS Tile Calorimeter

    CERN Document Server

    Henriques Correia, Ana Maria

    2015-01-01

    TileCal is the Hadronic calorimeter covering the most central region of the ATLAS experiment at the LHC. It uses iron plates as absorber and plastic scintillating tiles as the active material. Scintillation light produced in the tiles is transmitted by wavelength shifting fibres to photomultiplier tubes (PMTs). The resulting electronic signals from the approximately 10000 PMTs are measured and digitised every 25 ns before being transferred to off-detector data-acquisition systems. This contribution will review in a first part the performances of the calorimeter during run 1, obtained from calibration data, and from studies of the response of particles from collisions. In a second part it will present the solutions being investigated for the ongoing and future upgrades of the calorimeter electronics.

  15. The ATLAS Tile Calorimeter

    International Nuclear Information System (INIS)

    Henriques, A.

    2015-01-01

    TileCal is the Hadronic calorimeter covering the most central region of the ATLAS experiment at the LHC. It uses iron plates as absorber and plastic scintillating tiles as the active material. Scintillation light produced in the tiles is transmitted by wavelength shifting fibres to photomultiplier tubes (PMTs). The resulting electronic signals from the approximately 10000 PMTs are measured and digitised every 25 ns before being transferred to off-detector data-acquisition systems. This contribution will review in a first part the performances of the calorimeter during run 1, obtained from calibration data, and from studies of the response of particles from collisions. In a second part it will present the solutions being investigated for the ongoing and future upgrades of the calorimeter electronics. (authors)

  16. ALICE Zero Degree Calorimeter

    CERN Multimedia

    De Marco, N

    2013-01-01

    Two identical sets of calorimeters are located on both sides with respect to the beam Interaction Point (IP), 112.5 m away from it. Each set of detectors consists of a neutron (ZN) and a proton (ZP) Zero Degree Calorimeter (ZDC), positioned on remotely controlled platforms. The ZN is placed at zero degree with respect to the LHC beam axis, between the two beam pipes, while the ZP is positioned externally to the outgoing beam pipe. The spectator protons are separated from the ion beams by means of the dipole magnet D1.

  17. SLD liquid argon calorimeter

    International Nuclear Information System (INIS)

    Vella, E.

    1992-10-01

    The liquid argon calorimeter (LAC) of the SLD detector is a parallel plate -- liquid argon sampling calorimeter, used to measure particle energies in Z 0 decays at the Stanford Linear Collider. The LAC module design is based on a unique projective tower structure, in which lead plates and segmented lead tiles serve both as absorbers and electrodes. The LAC front end electronics incorporates several novel features, including extensive multiplexing and optical fiber readout, which take advantage of the low SLC beam crossing frequency. The operational performance of the LAC during the recently completed SLD physics run (which recorded over 10,000 Z 0 events) is discussed

  18. Modeling of Reaction Calorimeter

    OpenAIRE

    Farzad, Reza

    2014-01-01

    The purpose of this project was to model the reaction calorimeter in order to calculate the heat of absorption which is the most important parameter in this work. Reaction calorimeter is an apparatus which is used in measuring the heat of absorption of CO2 as well as the total pressure in vapor phase based on vapor-liquid equilibrium state. Mixture of monoethanolamine (MEA) and water was used as a solvent to absorb the CO2.Project was divided in to three parts in order to make the programming...

  19. A digital calorimeter

    International Nuclear Information System (INIS)

    Nitschke, J.M.

    1983-01-01

    The paper describes a calorimeter which is used to determine the particle flux of an accelerator. It incorporates as its principal feature a Peltier module which is operated in a constant current pulse mode. Via a feedback arrangement, the Peltier module thermally compensates the heat generated by the particle beam by supplying discrete 'cooling quanta'. The number of 'quanta' generated per unit time is measured with a frequency counter and is proportional to the beam power. The calorimeter can be calibrated via internal resistors which dissipate a precisely known amount of power in the target. (orig.)

  20. The SDC central calorimeter

    Energy Technology Data Exchange (ETDEWEB)

    Proudfoot, J.

    1992-01-01

    An overview of the calorimeter being designed and constructed by Solenoidal Detector Collaboration (SDC) for use at the Superconducting SuperCollider is presented. The collaboration have chosen to build a sampling calorimeter using scintillating tile with wavelength-shifter fiber readout as the detector medium, and absorber media of lead and iron for the electromagnetic and hadronic compartments. This choice was based on a substantial amount of R D and Monte Carlo simulation calculations, which showed that it both met the necessary experimental specifications in addition to being a cost effect design.

  1. The SDC central calorimeter

    Energy Technology Data Exchange (ETDEWEB)

    Proudfoot, J.; The SDC Collaboration

    1992-11-01

    An overview of the calorimeter being designed and constructed by Solenoidal Detector Collaboration (SDC) for use at the Superconducting SuperCollider is presented. The collaboration have chosen to build a sampling calorimeter using scintillating tile with wavelength-shifter fiber readout as the detector medium, and absorber media of lead and iron for the electromagnetic and hadronic compartments. This choice was based on a substantial amount of R&D and Monte Carlo simulation calculations, which showed that it both met the necessary experimental specifications in addition to being a cost effect design.

  2. A Flexible and Highly Sensitive Piezoresistive Pressure Sensor Based on Micropatterned Films Coated with Carbon Nanotubes

    Directory of Open Access Journals (Sweden)

    Jia-lin Yao

    2016-01-01

    Full Text Available Excellent flexibility, high sensitivity, and low consumption are essential characteristics in flexible microtube pressure sensing occasion, for example, implantable medical devices, industrial pipeline, and microfluidic chip. This paper reports a flexible, highly sensitive, and ultrathin piezoresistive pressure sensor for fluid pressure sensing, whose sensing element is micropatterned films with conductive carbon nanotube layer. The flexible pressure sensor, the thickness of which is 40 ± 10 μm, could be economically fabricated by using biocompatible polydimethylsiloxane (PDMS. Experimental results show that the flexible pressure sensor has high sensitivity (0.047 kPa−1 in gas sensing and 5.6 × 10−3 kPa−1 in liquid sensing and low consumption (<180 μW, and the sensor could be used to measure the pressure in curved microtubes.

  3. MAC calorimeters and applications

    International Nuclear Information System (INIS)

    MAC Collaboration.

    1982-03-01

    The MAC detector at PEP features a large solid-angle electromagnetic/hadronic calorimeter system, augmented by magnetic charged-particle tracking, muon analysis and scintillator triggering. Its implementation in the context of electron-positron annihilation physics is described, with emphasis on the utilization of calorimetry

  4. CMS Central Hadron Calorimeter

    OpenAIRE

    Budd, Howard S.

    2001-01-01

    We present a description of the CMS central hadron calorimeter. We describe the production of the 1996 CMS hadron testbeam module. We show the results of the quality control tests of the testbeam module. We present some results of the 1995 CMS hadron testbeam.

  5. Gas calorimeter workshop: proceedings

    International Nuclear Information System (INIS)

    1982-01-01

    Gas calorimeters combining functions of energy measurement and fine tracking have become more and more popular in the past few years. They help identify muons, gammas, electrons, and hadrons within dense tracks from transverse and longitudinal shower development. Fine segmentation capability using pads and strips on the cathodes have made gas-sampling calorimeters very attractive for colliding-beam detectors where a large multiplicity of particles are detected in a projected geometry. Linearity, energy resolution, shower position resolution, multishower resolution, and calibration questions were discussed in detail at the workshop. Ease of energy calibration by monitoring radioactive sources, good gain uniformity, and gain stability obtained were among the topics of the speakers. There was a discussion session on the operation mode of wire chambers. Gas calorimeters have been used successfully at CERN, Cornell, Fermilab, and SLAC for experiments. Some of the results from those large-scale devices were reported. Future usage of gas-sampling calorimeters for colliding-beam experiments at Fermilab and CERN were discussed. Wire chambers using extruded conductive plastic tubes have made construction easy of pads and strips which can conveniently read out induced signals from the cathode. The results of extensive studies on such devices were discussed. Separate entries were prepared for the data base for the 17 papers presented

  6. An Inexpensive Solution Calorimeter

    Science.gov (United States)

    Kavanagh, Emma; Mindel, Sam; Robertson, Giles; Hughes, D. E. Peter

    2008-01-01

    We describe the construction of a simple solution calorimeter, using a miniature bead thermistor as a temperature-sensing element. This has a response time of a few seconds and made it possible to carry out a thermometric reaction in under a minute, which led to minimal heat losses. Small temperature changes of 1 K associated with enthalpies of…

  7. Calorimeter for thermal sources

    International Nuclear Information System (INIS)

    Shai, I.; Shaham, Ch.; Barnea, I.

    1978-12-01

    A calorimeter was built, enabling the thermal power of radioactive sources to be measured in the range of 50 to 120 mW. The system was calibrated with an electrical heater. The calibration curves serve to determine the power of radioactive sources with a reasonable accuracy

  8. Automatic low-temperature calorimeter

    International Nuclear Information System (INIS)

    Malyshev, V.M.; Mil'ner, G.A.; Shibakin, V.F.; Sorkin, E.L.

    1986-01-01

    This paper describes a low-temperature adiabatic calorimeter with a range of 1.5-500K. The system for maintaining adiabatic conditions is implemented by two resitance thermometers, whose sensitivity at low temperatures is several orders higher than that of thermocouples. The calorimeter cryostat is installed in an STG-40 portable Dewar flask. The calorimeter is controlled by an Elektronika-60 microcomputer. Standard platinum and germanium thermometers were placed inside of the calorimeter to calibrate the thermometers of the calorimeter and the shield, and the specific heats of specimens of OSCh 11-4 copper and KTP-8 paste were measured to demonstrate the possibilities of the described calorimeter. Experience with the calorimeter has shown that a thorough study of the dependence of heat capacity on temperature (over 100 points for one specimen) can be performed in one or two dats

  9. Microfluidic Device

    Science.gov (United States)

    Tai, Yu-Chong (Inventor); Zheng, Siyang (Inventor); Lin, Jeffrey Chun-Hui (Inventor); Kasdan, Harvey L. (Inventor)

    2017-01-01

    Described herein are particular embodiments relating to a microfluidic device that may be utilized for cell sensing, counting, and/or sorting. Particular aspects relate to a microfabricated device that is capable of differentiating single cell types from dense cell populations. One particular embodiment relates a device and methods of using the same for sensing, counting, and/or sorting leukocytes from whole, undiluted blood samples.

  10. Heterogeneous catalysis in highly sensitive microreactors

    DEFF Research Database (Denmark)

    Olsen, Jakob Lind

    This thesis present a highly sensitive silicon microreactor and examples of its use in studying catalysis. The experimental setup built for gas handling and temperature control for the microreactor is described. The implementation of LabVIEW interfacing for all the experimental parts makes...

  11. Aluminum nanocantilevers for high sensitivity mass sensors

    DEFF Research Database (Denmark)

    Davis, Zachary James; Boisen, Anja

    2005-01-01

    We have fabricated Al nanocantilevers using a simple, one mask contact UV lithography technique with lateral and vertical dimensions under 500 and 100 nm, respectively. These devices are demonstrated as highly sensitive mass sensors by measuring their dynamic properties. Furthermore, it is shown ...

  12. Flow Type Bio-Chemical Calorimeter with Micro Differential Thermopile Sensor.

    Science.gov (United States)

    Saito, Masataka; Nakabeppu, Osamu

    2015-04-01

    Bio-chemical calorimeters with a MEMS (Micro-Electro-Mechanical Systems) thermopile sensor have been studied for monitoring detailed processes of the biochemical reactions of a minute sample with a high temporal resolution. The bio-calorimeters are generally divided into a batch-type and a flow-type. We developed a highly sensitive batch-type calorimeter which can detect a 100 nW level thermal reaction. However it shows a long settling time of 2 hours because of the heat capacity of a whole calorimeter. Thus, the flow-type calorimeters in passive and active mode have been studied for measuring the thermal reactions in an early stage after starting an analysis. The flow-type calorimeter consists of the MEMS differential thermopile sensor, a pair of micro channel reactor in a PDMS (polydimethylsiloxane) sheet in a three-fold thermostat chamber. The calorimeter in the passive mode was tested with dilution reactions of ethanol to water and NaCl aqueous solution to water. It was shown that the calorimeter detects exo- and endothermic reaction over 250 nW at solution flow rate of 0.05 ~ 1 µl/min with a settling time of about 4 minutes. In the active mode, a response test was conducted by using heat removal by water flow from the reactor channel. The active calorimetry enhances the response time about three to four times faster.

  13. ELECTROMAGNETIC CALORIMETER (ECAL)

    CERN Multimedia

    Roger Rusack

    Occupancy of the trigger primitives during a global run: the observed pattern is consistent with the polar angle dependence of the transverse energy equivalent of the electronic noise in the endcaps.   Progress on ECAL since the last CMS week has been mostly on three major fronts: we have continued with the installation and commissioning of the preshower detectors; the endcap calorimeter trigger has been installed and tested; and there have been many changes to the calorimeter detector control and safety systems. Both Preshower (ES) endcaps were installed in CMS on schedule, just before Easter. There followed a campaign of "first commissioning" to ensure that all services were correctly connected (electrical, optical, cooling, etc.). Apart from some optical ribbons that had to be replaced the process went rather smoothly, finishing on 23rd April. All power supplies are installed and operational. The cooling system (two branches of the joint Tracker-Preshower system) is fully fun...

  14. NA48 prototype calorimeter

    CERN Multimedia

    1990-01-01

    This is a calorimeter, a detector which measures the energy of particles. When in use, it is filled with liquid krypton at -152°C. Electrons and photons passing through interact with the krypton, creating a shower of charged particles which are collected on the copper ribbons. The ribbons are aligned to an accuracy of a tenth of a millimetre. The folding at each end allows them to be kept absolutely flat. Each shower of particles also creates a signal in scintillating material embedded in the support disks. These flashes of light are transmitted to electronics by the optical fibres along the side of the detector. They give the time at which the interaction occurred. The photo shows the calorimeter at NA48, a CERN experiment which is trying to understand the lack of anti-matter in the Universe today.

  15. UA2 central calorimeter

    CERN Multimedia

    The UA2 central calorimeter measured the energy of individual particles created in proton-antiproton collisions. Accurate calibration allowed the W and Z masses to be measured with a precision of about 1%. The calorimeter had 24 slices like this one, each weighing 4 tons. The slices were arranged like orange segments around the collision point. Incoming particles produced showers of secondary particles in the layers of heavy material. These showers passed through the layers of plastic scintillator, generating light which was taken by light guides (green) to the data collection electronics. The amount of light was proportional to the energy of the original particle. The inner 23 cm of lead and plastic sandwiches measured electrons and photons; the outer 80 cm of iron and plastic sandwiches measured strongly interacting hadrons. The detector was calibrated by injecting light through optical fibres or by placing a radioactive source in the tube on the bottom edge.

  16. Harwell Graphite Calorimeter

    International Nuclear Information System (INIS)

    Linacre, J.K.

    1970-01-01

    The calorimeter is of the steady state temperature difference type. It contains a graphite sample supported axially in a graphite outer jacket, the assembly being contained in a thin stainless steel outer can. The temperature of the jacket and the temperature difference between sample and jacket are measured by chromel-alumel thermocouples. The instrument is calibrated by means of an electric heater of low mass positioned on the axis of the sample. The resistance of the heater is known and both current through the heater and the potential across it may be measured. The instrument is filled with nitrogen at a pressure of one half atmosphere at room temperature. The calorimeter has been designed for prolonged operation at temperatures up to 600°C, and dose rates up to 1 Wg -1 , and instruments have been in use for periods in excess of one year

  17. The CMS Outer Hadron Calorimeter

    CERN Document Server

    Acharya, Bannaje Sripathi; Banerjee, Sunanda; Banerjee, Sudeshna; Bawa, Harinder Singh; Beri, Suman Bala; Bhandari, Virender; Bhatnagar, Vipin; Chendvankar, Sanjay; Deshpande, Pandurang Vishnu; Dugad, Shashikant; Ganguli, Som N; Guchait, Monoranjan; Gurtu, Atul; Kalmani, Suresh Devendrappa; Kaur, Manjit; Kohli, Jatinder Mohan; Krishnaswamy, Marthi Ramaswamy; Kumar, Arun; Maity, Manas; Majumder, Gobinda; Mazumdar, Kajari; Mondal, Naba Kumar; Nagaraj, P; Narasimham, Vemuri Syamala; Patil, Mandakini Ravindra; Reddy, L V; Satyanarayana, B; Sharma, Seema; Singh, B; Singh, Jas Bir; Sudhakar, Katta; Tonwar, Suresh C; Verma, Piyush

    2006-01-01

    The CMS hadron calorimeter is a sampling calorimeter with brass absorber and plastic scintillator tiles with wavelength shifting fibres for carrying the light to the readout device. The barrel hadron calorimeter is complemented with a outer calorimeter to ensure high energy shower containment in CMS and thus working as a tail catcher. Fabrication, testing and calibrations of the outer hadron calorimeter are carried out keeping in mind its importance in the energy measurement of jets in view of linearity and resolution. It will provide a net improvement in missing $\\et$ measurements at LHC energies. The outer hadron calorimeter has a very good signal to background ratio even for a minimum ionising particle and can hence be used in coincidence with the Resistive Plate Chambers of the CMS detector for the muon trigger.

  18. The CMS crystal calorimeter

    CERN Document Server

    Lustermann, W

    2004-01-01

    The measurement of the energy of electrons and photons with very high accuracy is of primary importance far the study of many physics processes at the Large Hadron Collider (LHC), in particular for the search of the Higgs Boson. The CMS experiment will use a crystal calorimeter with pointing geometry, almost covering 4p, as it offers a very good energy resolution. It is divided into a barrel composed of 61200 lead tungstate crystals, two end-caps with 14648 crystals and a pre-shower detector in front of the end-cap. The challenges of the calorimeter design arise from the high radiation environment, the 4 Tesla magnetic eld, the high bunch crossing rate of 40 MHz and the large dynamic range, requiring the development of fast, radiation hard crystals, photo-detectors and readout electronics. An overview of the construction and design of the calorimeter will be presented, with emphasis on some of the details required to meet the demanding performance goals. 19 Refs.

  19. Precision titration mini-calorimeter

    International Nuclear Information System (INIS)

    Ensor, D.; Kullberg, L.; Choppin, G.

    1977-01-01

    The design and test of a small volume calorimeter of high precision and simple design is described. The calorimeter operates with solution sample volumes in the range of 3 to 5 ml. The results of experiments on the entropy changes for two standard reactions: (1) reaction of tris(hydroxymethyl)aminomethane with hydrochloric acid and (2) reaction between mercury(II) and bromide ions are reported to confirm the accuracy and overall performance of the calorimeter

  20. Microfluidic interconnects

    Science.gov (United States)

    Benett, William J.; Krulevitch, Peter A.

    2001-01-01

    A miniature connector for introducing microliter quantities of solutions into microfabricated fluidic devices. The fluidic connector, for example, joins standard high pressure liquid chromatography (HPLC) tubing to 1 mm diameter holes in silicon or glass, enabling ml-sized volumes of sample solutions to be merged with .mu.l-sized devices. The connector has many features, including ease of connect and disconnect; a small footprint which enables numerous connectors to be located in a small area; low dead volume; helium leak-tight; and tubing does not twist during connection. Thus the connector enables easy and effective change of microfluidic devices and introduction of different solutions in the devices.

  1. Low Cost, Low Power, High Sensitivity Magnetometer

    Science.gov (United States)

    2008-12-01

    which are used to measure the small magnetic signals from brain. Other types of vector magnetometers are fluxgate , coil based, and magnetoresistance...concentrator with the magnetometer currently used in Army multimodal sensor systems, the Brown fluxgate . One sees the MEMS fluxgate magnetometer is...Guedes, A.; et al., 2008: Hybrid - LOW COST, LOW POWER, HIGH SENSITIVITY MAGNETOMETER A.S. Edelstein*, James E. Burnette, Greg A. Fischer, M.G

  2. Advanced Thin Ionization Calorimeter (ATIC)

    Science.gov (United States)

    Wefel, John P.

    1998-01-01

    This is the final report for NASA grant NAGW-4577, "Advanced Thin Ionization Calorimeter (ATIC)". This grant covered a joint project between LSU and the University of Maryland for a Concept Study of a new type of fully active calorimeter to be used to measure the energy spectra of very high energy cosmic rays, particularly Hydrogen and Helium, to beyond 1014 eV. This very high energy region has been studied with emulsion chamber techniques, but never investigated with electronic calorimeters. Technology had advanced to the point that a fully active calorimeter based upon Bismuth Germanate (BGO) scintillating crystals appeared feasible for balloon flight (and eventually space) experiments.

  3. Physics and Applications of Metallic Magnetic Calorimeters

    Science.gov (United States)

    Kempf, S.; Fleischmann, A.; Gastaldo, L.; Enss, C.

    2018-03-01

    Metallic magnetic calorimeters (MMCs) are calorimetric low-temperature particle detectors that are currently strongly advancing the state of the art in energy-dispersive single particle detection. They are typically operated at temperatures below 100 mK and make use of a metallic, paramagnetic temperature sensor to transduce the temperature rise of the detector upon the absorption of an energetic particle into a change of magnetic flux which is sensed by a superconducting quantum interference device. This outstanding interplay between a high-sensitivity thermometer and a near quantum-limited amplifier results in a very fast signal rise time, an excellent energy resolution, a large dynamic range, a quantum efficiency close to 100% as well as an almost ideal linear detector response. For this reason, a growing number of groups located all over the world is developing MMC arrays of various sizes which are routinely used in a variety of applications. Within this paper, we briefly review the state of the art of metallic magnetic calorimeters. This includes a discussion of the detection principle, sensor materials and detector geometries, readout concepts, the structure of modern detectors as well as the state-of-the-art detector performance.

  4. Review of high-sensitivity Radon studies

    Science.gov (United States)

    Wojcik, M.; Zuzel, G.; Simgen, H.

    2017-10-01

    A challenge in many present cutting-edge particle physics experiments is the stringent requirements in terms of radioactive background. In peculiar, the prevention of Radon, a radioactive noble gas, which occurs from ambient air and it is also released by emanation from the omnipresent progenitor Radium. In this paper we review various high-sensitivity Radon detection techniques and approaches, applied in the experiments looking for rare nuclear processes happening at low energies. They allow to identify, quantitatively measure and finally suppress the numerous sources of Radon in the detectors’ components and plants.

  5. High sensitivity optical molecular imaging system

    Science.gov (United States)

    An, Yu; Yuan, Gao; Huang, Chao; Jiang, Shixin; Zhang, Peng; Wang, Kun; Tian, Jie

    2018-02-01

    Optical Molecular Imaging (OMI) has the advantages of high sensitivity, low cost and ease of use. By labeling the regions of interest with fluorescent or bioluminescence probes, OMI can noninvasively obtain the distribution of the probes in vivo, which play the key role in cancer research, pharmacokinetics and other biological studies. In preclinical and clinical application, the image depth, resolution and sensitivity are the key factors for researchers to use OMI. In this paper, we report a high sensitivity optical molecular imaging system developed by our group, which can improve the imaging depth in phantom to nearly 5cm, high resolution at 2cm depth, and high image sensitivity. To validate the performance of the system, special designed phantom experiments and weak light detection experiment were implemented. The results shows that cooperated with high performance electron-multiplying charge coupled device (EMCCD) camera, precision design of light path system and high efficient image techniques, our OMI system can simultaneously collect the light-emitted signals generated by fluorescence molecular imaging, bioluminescence imaging, Cherenkov luminance and other optical imaging modality, and observe the internal distribution of light-emitting agents fast and accurately.

  6. High sensitivity troponin and valvular heart disease.

    Science.gov (United States)

    McCarthy, Cian P; Donnellan, Eoin; Phelan, Dermot; Griffin, Brian P; Enriquez-Sarano, Maurice; McEvoy, John W

    2017-07-01

    Blood-based biomarkers have been extensively studied in a range of cardiovascular diseases and have established utility in routine clinical care, most notably in the diagnosis of acute coronary syndrome (e.g., troponin) and the management of heart failure (e.g., brain-natriuretic peptide). The role of biomarkers is less well established in the management of valvular heart disease (VHD), in which the optimal timing of surgical intervention is often challenging. One promising biomarker that has been the subject of a number of recent VHD research studies is high sensitivity troponin (hs-cTn). Novel high-sensitivity assays can detect subclinical myocardial damage in asymptomatic individuals. Thus, hs-cTn may have utility in the assessment of asymptomatic patients with severe VHD who do not have a clear traditional indication for surgical intervention. In this state-of-the-art review, we examine the current evidence for hs-cTn as a potential biomarker in the most commonly encountered VHD conditions, aortic stenosis and mitral regurgitation. This review provides a synopsis of early evidence indicating that hs-cTn has promise as a biomarker in VHD. However, the impact of its measurement on clinical practice and VHD outcomes needs to be further assessed in prospective studies before routine clinical use becomes a reality. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. Polymer dual ring resonators for label-free optical biosensing using microfluidics.

    Science.gov (United States)

    Salleh, Muhammad H M; Glidle, Andrew; Sorel, Marc; Reboud, Julien; Cooper, Jonathan M

    2013-04-18

    We demonstrate a polymer resonator microfluidic biosensor that overcomes the complex manufacturing procedures required to fabricate traditional devices. In this new format, we show that a gapless light coupling photonic configuration, fabricated in SU8 polymer, can achieve high sensitivity, label-free chemical sensing in solution and high sensitivity biological sensing, at visible wavelengths.

  8. ELECTROMAGNET CALORIMETER (ECAL)

    CERN Multimedia

    R. Rusack

    Installation is under way of the last piece of the electromagnetic calorimeter. This is the preshower (ES) that sits in front of the two endcap calorimeters. The construction of the ES was completed in December and went through a detailed set of tests in December and January. The two preshower detectors have a total of 4300 silicon sensors with 137,000 strips. After final assembly and system testing in January, only two of the strips were found to be defective. Once CMS was fully opened a new support structure (‘Gazprom’) was put into place underneath the beam pipe, to support the Surkov platform, on which the preshower installation takes place. In the early hours of 26th February the first two Dees, which form the ‘ES+’ endcap,  were transported to P5 , a journey that took two and a half hours. The Dees, still inside environmental protection boxes, were then lowered  underground and moved to the ‘+’ end of CMS. Installation start...

  9. ELECTROMAGNETIC CALORIMETER (ECAL)

    CERN Multimedia

    P. Bloch

    ECAL crystal calorimeter (EB + EE) The Barrel and Endcaps ECAL calorimeters have been used routinely in global runs. The CRAFT data have confirmed that ECAL performance is the same with or without magnetic field. The CRUZET and CRAFT runs have allowed experience to be gained with ECAL operation in many areas, in particular for the trigger and the calibration sequence using gap events (laser events and LED pulsing). More details can be found in the Commissioning/DPG report in this bulletin.   The last components remaining to be installed and commissioned are the specific Endcap Trigger modules (TCC-48). Most of the modules have been delivered to LLR and half of them are already at CERN. In parallel, large progress has been made on the validation of the TCC-48 firmware. Preshower (ES) The Preshower project has also made impressive progress during Autumn. All the elements required to complete the detector assembly are at hand. Ladder assembly, test and calibration with cosmic rays at the operating ...

  10. HADRON CALORIMETER (HCAL)

    CERN Multimedia

    A. Skuja

    Central Calorimeter (HB/HE/HO) Photodetectors The main activity of the HCAL group during the present shutdown is the replacement of a small fraction of the Central Calorimeter (HB/HE/HO) photodetectors -- the Hybrid Photo-Detectors (HPDs). During the MTCC of 2006 it was established that all HPDs exhibit a low rate of discharge generating large random pulses. This behaviour persists at the full CMS field. However, at relatively low fields (0.5 Tesla) this discharge rate increases dramatically and becomes very large for a fraction of the HPDs. The HO HPDs which sit in the gap of the return yoke are thus adversly affected. These discharge pulses have been labelled "HPD noise" (which must be distinguished from low level electronic noise which manifests itself as pedestal noise for all HPD readout channels). Additional intermediate level noise can be generated by ion-feedback arising from thermal and field emission electrons. Ion feedback noise never exceeds the equivalent of few 10s of GeV, the...

  11. The LHCb hadron calorimeter

    International Nuclear Information System (INIS)

    Dzhelyadin, R.I.

    2002-01-01

    The Hadron Calorimeter (HCAL) is designed for the LHCb experiment. The main purpose of the detector is to provide data for the L0 hadron trigger. The HCAL is designed as consisting of two symmetric movable parts of about 500 ton in total getting in touch in operation position without non-instrumented zones. The lateral dimensions of an active area are X=8.4 m width, Y=6.8 m height, and is distanced from the interaction point at Z=13.33 m. Both halves are assembled from stacked up modules. An internal structure consisting of thin iron plates interspaced with scintillating tiles has been chosen. Attention is paid to optimize the detector according to the requirements of the experiment, reducing the spending needed for its construction. Different construction technologies are being discussed. The calorimeter properties have been extensively studied with a variety of prototype on the accelerator beam. The calibration with a radioactive source and module-0 construction experience is discussed

  12. CALDER: High-sensitivity cryogenic light detectors

    International Nuclear Information System (INIS)

    Casali, N.; Bellini, F.; Cardani, L.

    2017-01-01

    The current bolometric experiments searching for rare processes such as neutrinoless double-beta decay or dark matter interaction demand for cryogenic light detectors with high sensitivity, large active area and excellent scalability and radio-purity in order to reduce their background budget. The CALDER project aims to develop such kind of light detectors implementing phonon-mediated Kinetic Inductance Detectors (KIDs). The goal for this project is the realization of a 5 × 5 cm"2 light detector working between 10 and 100mK with a baseline resolution RMS below 20 eV. In this work the characteristics and the performances of the prototype detectors developed in the first project phase will be shown.

  13. Highly sensitive microcalorimeters for radiation research

    International Nuclear Information System (INIS)

    Avaev, V.N.; Demchuk, B.N.; Ioffe, L.A.; Efimov, E.P.

    1984-01-01

    Calorimetry is used in research at various types of nuclear-physics installations to obtain information on the quantitative and qualitative composition of ionizing radiation in a reactor core and in the surrounding layers of the biological shield. In this paper, the authors examine the characteristics of highly sensitive microcalorimeters with modular semiconductor heat pickups designed for operation in reactor channels. The microcalorimeters have a thin-walled aluminum housing on whose inner surface modular heat pickups are placed radially as shown here. The results of measurements of the temperature dependence of the sensitivity of the microcalorimeters are shown. The results of measuring the sensitivity of a PMK-2 microcalorimeter assembly as a function of integrated neutron flux for three energy intervals and the adsorbed gamma energy are shown. In order to study specimens with different shapes and sizes, microcalorimeters with chambers in the form of cylinders and a parallelepiped were built and tested

  14. Microfluidic sieve valves

    Science.gov (United States)

    Quake, Stephen R; Marcus, Joshua S; Hansen, Carl L

    2015-01-13

    Sieve valves for use in microfluidic device are provided. The valves are useful for impeding the flow of particles, such as chromatography beads or cells, in a microfluidic channel while allowing liquid solution to pass through the valve. The valves find particular use in making microfluidic chromatography modules.

  15. Microfluidic Dye Lasers

    DEFF Research Database (Denmark)

    Kristensen, Anders; Balslev, Søren; Gersborg-Hansen, Morten

    2006-01-01

    A technology for miniaturized, polymer based lasers, suitable for integration with planar waveguides and microfluidic networks is presented. The microfluidic dye laser device consists of a microfluidic channel with an embedded optical resonator. The devices are fabricated in a thin polymer film...

  16. Resonator graphene microfluidic antenna (RGMA) for blood glucose detection

    Science.gov (United States)

    Jizat, Noorlindawaty Md.; Mohamad, Su Natasha; Ishak, Muhammad Ikman

    2017-09-01

    Graphene is capable of highly sensitive analyte detection due to its nanoscale nature. Here we show a resonator graphene microfluidic antenna (RGMA) is used to detect the dielectric properties of aqueous glucose solution which represent the glucose level in blood. Simulation verified the high sensitivity of proposed RGMA made with aqueous glucose solutions at different concentrations. The RGMA yielded a sensor sensitivity of 0.1882GHz/mgml-1 as plotted from the slope of the linear fit from the result averages in S11 and S21 parameter, respectively. This results indicate that the proposed resonator antenna achieves high sensitivity and linear to the changes of glucose concentration.

  17. CMS hadronic forward calorimeter

    International Nuclear Information System (INIS)

    Merlo, J.P.

    1998-01-01

    Tests of quartz fiber prototypes, based on the detection of Cherenkov light from showering particles, demonstrate a detector possessing all of the desirable characteristics for a forward calorimeter. A prototype for the CMS experiment consists of 0.3 mm diameter fibers embedded in a copper matrix. The response to high energy (10-375 GeV) electrons, pions, protons and muons, the light yield, energy and position resolutions, and signal uniformity and linearity, are discussed. The signal generation mechanism gives this type of detector unique properties, especially for the detection of hadronic showers: Narrow, shallow shower profiles, hermeticity and extremely fast signals. The implications for measurements in the high-rate, high-radiation LHC environment are discussed. (orig.)

  18. Nemo-3 calorimeter electronics

    International Nuclear Information System (INIS)

    Bernaudin, P.; Cheikali, C.; Lavigne, B.; Richard, A.; Lebris, J.

    2000-11-01

    The calorimeter electronics of the NEMO-3 double beta decay experiment fulfills three functions: -energy measurement of the electrons by measuring the charge of the pulses, - time measurement, - fast first level triggering. The electronics of the 1940 Scintillator-PM modules is implemented as 40 '9U x 400 mm VME' boards of up to 51 channels. For each channel the analog signals conditioning is implemented as one SMD daughter board. Each board performs 12 bit charge measurements with 0.35 pC charge resolution, 12 bit time measurements with 50 ps time resolution and a fast analog multiplicity level for triggering. The total handling and conversion time for all the channels is less than 100 μs. The electronics will be presented as well as the test system. (authors)

  19. D0 calorimeter electronics

    International Nuclear Information System (INIS)

    Schamberger, R.D.

    1991-01-01

    A detailed description of the electronics used to readout the signals from the D0 Uranium-Liquid Argon Calorimeter is presented. The three major components of the readout system are the charge sensitive preamps, the shaping and sample and hold circuits, and the Analog to Digital converters. The very low noise preamps achieve an input noise equivalent to 2000e's + 3000e's per nanofarad of input capacitance. The coherent noise in the system is very low, less than 1/20 of an ADC count which is equivalent to about 200 KeV of energy incident on the detector. The ADC system contains a 12 bit, 5 μsecond successive approximation digitizer. We maintain a 15 bit dynamic range by automatically amplifying small signals after they are held, but before digitization. The ADC also contains pedestal and limit memory, to allow (on a channel by channel basis) offset subtraction, and suppression of small signals, symmetrically around zero signal. (orig.)

  20. Cerenkov fiber sampling calorimeters

    International Nuclear Information System (INIS)

    Arrington, K.; Kefford, D.; Kennedy, J.; Pisani, R.; Sanzeni, C.; Segall, K.; Wall, D.; Winn, D.R.; Carey, R.; Dye, S.; Miller, J.; Sulak, L.; Worstell, W.; Efremenko, Y.; Kamyshkov, Y.; Savin, A.; Shmakov, K.; Tarkovsky, E.

    1994-01-01

    Clear optical fibers were used as a Cerenkov sampling media in Pb (electromagnetic) and Cu (hadron) absorbers in spaghetti calorimeters, for high rate and high radiation dose experiments, such as the forward region of high energy colliders. The fiber axes were aligned close to the direction of the incident particles (1 degree--7 degree). The 7 λ deep hadron tower contained 2.8% by volume 1.5 mm diameter core clear plastic fibers. The 27 radiation length deep electromagnetic towers had packing fractions of 6.8% and 7.2% of 1 mm diameter core quartz fibers as the active Cerenkov sampling medium. The energy resolution on electrons and pions, energy response, pulse shapes and angular studies are presented

  1. Electromagnetic shower detector-calorimeters

    International Nuclear Information System (INIS)

    Appel, J.A.

    1975-01-01

    A brief review of the state-of-the-art of electromagnetic calorimeters is presented. The choice of detector based on the experimental requirements in cost, spatial resolution, energy resolution, and hadron rejection is discussed

  2. Highly sensitive detection of a current ripple

    International Nuclear Information System (INIS)

    Aoki, Takashi; Gushiken, Tutomu; Nishikigouri, Kazutaka; Kumada, Masayuki.

    1996-01-01

    In the HIMAC, there are six thyristor-controlled power sources for driving two synchrotrons. These power sources are the three-output terminal power sources which are equipped with positive output, negative output and neutral point for the common mode countermeasures. As electromagnet circuits are connected to the three-output terminal power sources, those are three-line type. In the inside of the power source circuits controlled by thyristors, there is the oscillation peculiar to the power sources, and the variation of voltage induces current spikes. This time, in order to assess the results of the common mode countermeasures in the power source and electromagnet circuits, as one method of cross-check, it is considered that since electromagnet current flows being divided to the bridging resistance and the coil, if attention is paid to the current on bridging resistance side, the ripple components of common mode and normal mode can be detected with high sensitivity, and this was verified. The present state of heightening the performance of synchrotron power sources is explained. The cross-check of the method of assessing the performance of electromagnet power sources is reported. The method of measuring ripple current and the results of the measurement are reported. (K.I.)

  3. Development of high sensitivity radon detectors

    CERN Document Server

    Takeuchi, Y; Kajita, T; Tasaka, S; Hori, H; Nemoto, M; Okazawa, H

    1999-01-01

    High sensitivity detectors for radon in air and in water have been developed. We use electrostatic collection and a PIN photodiode for these detectors. Calibration systems have been also constructed to obtain collection factors. As a result of the calibration study, the absolute humidity dependence of the radon detector for air is clearly observed in the region less than about 1.6 g/m sup 3. The calibration factors of the radon detector for air are 2.2+-0.2 (counts/day)/(mBq/m sup 3) at 0.08 g/m sup 3 and 0.86+-0.06 (counts/day)/(mBq/m sup 3) at 11 g/m sup 3. The calibration factor of the radon detector for water is 3.6+-0.5 (counts/day)/(mBq/m sup 3). The background level of the radon detector for air is 2.4+-1.3 counts/day. As a result, one standard deviation excess of the signal above the background of the radon detector for air should be possible for 1.4 mBq/m sup 3 in a one-day measurement at 0.08 g/m sup 3.

  4. Scintillating plate calorimeter optical design

    International Nuclear Information System (INIS)

    McNeil, R.; Fazely, A.; Gunasingha, R.; Imlay, R.; Lim, J.

    1990-01-01

    A major technical challenge facing the builder of a general purpose detector for the SSC is to achieve an optimum design for the calorimeter. Because of its fast response and good energy resolution, scintillating plate sampling calorimeters should be considered as a possible technology option. The work of the Scintillating Plate Calorimeter Collaboration is focused on compensating plate calorimeters. Based on experimental and simulation studies, it is expected that a sampling calorimeter with alternating layers of high-Z absorber (Pb, W, DU, etc.) and plastic scintillator can be made compensating (e/h = 1.00) by suitable choice of the ratio of absorber/scintillator thickness. Two conceptual designs have been pursued by this subsystem collaboration. One is based on lead as the absorber, with read/out of the scintillator plates via wavelength shifter fibers. The other design is based on depleted uranium as the absorber with wavelength shifter (WLS) plate readout. Progress on designs for the optical readout of a compensating scintillator plate calorimeter are presented. These designs include readout of the scintillator plates via wavelength shifter plates or fiber readout. Results from radiation damage studies of the optical components are presented

  5. High sensitivity amplifier/discriminator for PWC's

    International Nuclear Information System (INIS)

    Hansen, S.

    1983-01-01

    The facility support group at Fermilab is designing and building a general purpose beam chamber for use in several locations at the laboratory. This pwc has 128 wires per plane spaced 1 mm apart. An initial production of 25 signal planes is anticipated. In proportional chambers, the size of the signal depends exponentially on the charge stored per unit of length along the anode wire. As the wire spacing decreases, the capacitance per unit length decreases, thereby requiring increased applied voltage to restore the necessary charge per unit length. In practical terms, this phenomenon is responsible for difficulties in constructing chambers with less than 2 mm wire spacing. 1 mm chambers, therefore, are frequently operated very near to their breakdown point and/or a high gain gas containing organic compounds such as magic gas is used. This argon/iso-butane mixture has three drawbacks: it is explosive when exposed to the air, it leaves a residue on the wires after extended use and is costly. An amplifier with higher sensitivity would reduce the problems associated with operating chambers with small wire spacings and allow them to be run a safe margin below their breakdown voltage even with an inorganic gas mixture such as argon/CO2, this eliminating the need to use magic gas. Described here is a low cost amplifier with a usable threshold of less than 0.5 μA. Data on the performance of this amplifier/discriminator in operation on a prototype beam chamber are given. This data shows the advantages of the high sensitivity of this design

  6. HADRON CALORIMETER (HCAL)

    CERN Multimedia

    J. Spalding

    2011-01-01

    All the HCAL calorimeters are ready for data-taking in 2011 and participated fully in the cosmic running and initial beam operations in the last few weeks. Several improvements were made during the winter technical stop, including replacement of the light-guide sleeves in HF, improvements to the low voltage power connections, and separation of HF from HB and HE in the DAQ partitions. During the 2010 running a form of anomalous noise in the HF was identified as being caused by scintillation when charged particles pass through a portion of the air light-guide sleeve. This portion was constructed from a non-conductive mirror-like material called “HEM”. To suppress these anomalous signals, during the recent winter technical stop all sleeves in the detector were replaced with sleeves made of Tyvek. The detector has been recommissioned with all channels fully operational. Recalibration of the detector will be required due to the differing reflectivity of the new sleeves compared with the HEM sl...

  7. HADRON CALORIMETER (HCAL)

    CERN Multimedia

    D. Green

    The organization of CMS HCAL contains four “geographic” efforts, HB, HO, HE and HF. In addition there are presently five “common” HCAL activities. These ef¬forts are concentrated on electronics, on controls (DCS), on physics objects (JetMet), on Installation and Commissioning (I&C), and on Test Beam (TB) and Cosmic Challenge (MTCC) data taking. HCAL has begun planning to re-organize to be synchronized with the overall CMS management structure. HF The full production of the wedges is completed for some time. The 2004 test beam work has established the radioactive source calibration system for HF works at the 5 % level or better and a note is completed. The calibration of the complete HF is complete. HF is now in the UX cavern and will be hooked up and read out as soon as the services are available. HE The two HE calorimeters are installed and an initial calibration has been established. In the MTCC the HE was read out and muon data was observed. Event b...

  8. HADRON CALORIMETER (HCAL)

    CERN Multimedia

    J. Spalding and A. Skuja

    2010-01-01

    Splash and Collision Data HCAL recorded the beam-on-collimator (splash) and the first collision data in November and December 2009, and provided triggers to CMS with the forward calorimeter, HF. Splash events were used to improve the energy inter-calibration of the HB and HE channels, with the basic assumption that the energy deposited in the detector by the large flux of muons that passed through in splash events was a smooth function in eta and phi. The new HB and HE calibration coefficients were applied prior to the collision data taking. For HO, a similar analysis is being finalized. Splash events were also used to determine the relative timing between channels in HB and HE, and new delay settings were calculated based on splashes from one beam, applied and verified with the splash events from the other beam. During Fall 2009, the HF technical trigger was improved in order to be effectively used as one of the main CMS triggers during the collision data taking. Collisions were successfully recorded by all...

  9. HADRON CALORIMETER (HCAL)

    CERN Multimedia

    by J. Spalding and A. Skuja

    2010-01-01

    Operations and Maintenance All HCAL sub-detectors participated throughout the recent data taking with 7 TeV collisions. A timing scan of HF was performed to optimize the timing across the detectors and to set the overall time position of the ~10-ns wide signals within the 25-ns integration time slice. This position was chosen to ensure that the trigger primitives in physics events are generated synchronously at the desired bunch crossing, while also providing discrimination between the calorimeter signals and anomalous signals due to interactions within the photomultiplier tubes. This timing discrimination is now used in the standard filter algorithms for anomalous signals. For HB and HE, once the statistics needed to assess the timing of a sufficient number of channels was accumulated, it was verified that the time settings determined with cosmic, splash events and initial collision data were appropriate for the 7 TeV collision data taking. A further fine-tuning of the HB and HE time settings will be perfo...

  10. Calorimeter Process Variable Archiving

    International Nuclear Information System (INIS)

    Huffman, David

    2002-01-01

    These steps were taken to maintain weekly archives: (1) Friday morning you stop the archiver and wait for it to finish writing data (the lock file will be removed from the directory); (2) move the current archive information to a PC via FTP; (3) remove all previous archive information in the previous directory; (4) move the current archive into the previous directory; (5) start a new archive; (6) burn a CDROM of the archive; and (7) copy the current archive to a specific directory. There are 2 ways to check if the Calorimeter Archiver is running, either through the WEB based front end or directly from a command line. Once the archiver is running it can be monitored from a WEB page. This only works with a browser launched from the online machine running the archiver. Each time the browser is reloaded there should be an update reported in the last write check field. You might have to wait a few minutes to see the update. Calorimetry currently takes readings every (300 sec.) 5 minutes. The second method to verify the archiver is running is to issue a command from a Linux cluster machine.

  11. HADRON CALORIMETER (HCAL)

    CERN Multimedia

    A. Skuja

    During the last 3 months commissioning of HCAL has continued for HO and HE+. We have also started the commissioning of the first wedge of HB+. Progress continues to be made by our Trigger/DAQ, DCS and DPG colleagues. HF will be used to obtain a Luminosity measurement for CMS. A first test of the modifications to the HF electronics was made in the August CMS global run. In addition to installation and commissioning of various parts of HCAL, we also completed a very successful summer Test Beam period which saw measurements of the combined HE/EE/ES calorimeter system in the H2 test beam. Installation and Commissioning a. HB commissioning This week, part of the final water-cooling system for HB was commissioned. Eighteen HB- wedges and two pilot wedges on HB+ have been connected to the water circuit on YB0. On Sept 6, 2007 cabling and commissioning was started for the first HB readout box (RBX) using temporary set of cables. We have connected RBX-17 to the Low Voltage PS and the HCAL Detector Control Sy...

  12. HADRON CALORIMETER (HCAL)

    CERN Multimedia

    A. Skuja

    Since the beginning of 2007, HCAL has made significant progress in the installation and commissioning of both hardware and software. A large fraction of the physical Hadron Calorimeter modules have been installed in UX5. In fact, the only missing pieces are HE- and part of HO. The HB+/- were installed in the cryostat in March. HB scintillator layer-17 was installed above ground before the HB were lowered. The HB- scintillator layer-0 was installed immediately after completion of EB- installation. HF/HCAL Commissioning The commissioning and checkout of the HCAL readout electronics is also proceeding at a rapid pace in Bldg. 904 and USC55. All sixteen crates of HCAL VME readout electronics have been commissioned and certified for service. Fifteen are currently operating in the S2 level of USC55. The last crate is being used for firmware development in the Electronics Integration Facility in 904. All installed crates are interfaced to their VME computers and receive synchronous control from the fully-equipp...

  13. HADRON CALORIMETER (HCAL)

    CERN Multimedia

    J. Spalding

    2011-01-01

    Throughout the entire proton-proton run of 2011, all HCAL calorimeters operated very efficiently. Over 99% of HCAL readout and trigger channels were alive. However, during the year we did face two hardware problems. One major operation problem was the occasional loss of data from a single RBX caused by single event upsets (SEUs). The rate of RBX data loss was on average one incident per 10 pb–1 of integrated luminosity. This led to approximately 1% of CMS data loss. In order to mitigate this problem, HCAL has introduced an automatic reset of the RBX. With this reset, full operation was restored within about one minute. The final hardware correction of the problem will be possible only during a long shutdown (LS1) in 2013-’14. Another hardware problem that developed in 2011 was the failure of QPLL (quartz phase lock loops) chips. This led to the loss of phase of the readout clock with respect to the LHC clock. As a consequence, in two sections in HCAL (10 degree in φ on HB and 1...

  14. ELECTROMAGNETIC CALORIMETER (ECAL)

    CERN Multimedia

    P. Bloch

    ECAL Barrel (EB) The cabling of the ECAL Barrel services on YB0 was completed early December 2007. The team has now commissioned the complete Barrel. To run all the supermodules in parallel, it is necessary to remove the heat from the service cables on YB0. The corresponding thermal screens are being installed and, for the time being, a max¬imum of 25 supermodules has been run concurrently. EB is read out regularly with a local DAQ as well as with the central DAQ and trigger. The calorimeter trigger has also been commissioned, allowing us to trigger on cosmic muons. ECAL Endcaps (EE) The Endcaps crystal production will be completed before the end of March 2008, as planned. The gluing of the VPTs (Vacuum Photo Triodes) on the crystals and the assembly of Supercrystals (sets of 25 crystals) are proceeding at the pace of 16 Supercrystals (400 channels) per week. Two thirds of the Supercrystals needed for the complete EE have been produced. Their mounting on the Dee backplates (including the connectio...

  15. HADRON CALORIMETER (HCAL)

    CERN Multimedia

    A. Skuja

    HCAL installation and commissioning is approaching completion. Work continues on commissioning of HE-, HF- and the minus wheels of HO. We expect that all commissioning will be completed by mid-March. HCAL commissioning is interleaved with integration of HCAL and the Global Calorimeter Trigger (GCT). HCAL is attempting to take data using the HPD self-trigger as part of the GCT trigger path. Initial attempts in mid-February have not succeeded. Work continues on HCAL and the GCT. HPD lifetimes at 4 Tesla are being measured in Princeton. After more than a month of testing in a 4 Tesla field there are no sur¬prises. As the lifetime measurements proceed, the HPD response at intermediate fields of 1 Tesla will be verified and analyzed. Work also continues on HCAL calibration and DCS/DSS at Point 5. More details for some of the subsystems are presented in what follows. HE HE plus The cooling system of HE+ is functional now. The HE+ final connections to the LV system are complete. LV and HV tests to ev...

  16. The CPLEAR Electromagnetic Calorimeter

    CERN Document Server

    Adler, R; Bal, F; Behnke, O; Bloch, P; Damianoglou, D; Dechelette, Paul; Dröge, M; Eckart, B; Felder, C; Fetscher, W; Fidecaro, Maria; Garreta, D; Gerber, H J; Gumplinger, P; Guyon, D; Johner, H U; Löfstedt, B; Kern, J; Kokkas, P; Krause, H; Mall, U; Marin, C P; Nanni, F; Pagels, B; Pavlopoulos, P; Petit, P; Polivka, G; Rheme, C; Ruf, T; Santoni, C; Schaller, L A; Schopper, A; Tauscher, Ludwig; Tschopp, H; Weber, P; Wendler, H; Witzig, C; Wolter, M

    1997-01-01

    A large-acceptance lead/gas sampling electromagnetic calorimeter (ECAL) was constructed for the CPLEAR experiment to detect photons from decays of $\\pi^0$s with momentum $p_{\\pi^0} \\le 800$ MeV$/c$. The main purpose of the ECAL is to determine the decay vertex of neutral-kaon decays $\\ko \\rightarrow \\pi^0\\pi^0 \\rightarrow 4 \\gamma$ and $\\ko \\rightarrow \\pi^0\\pi^0\\pi^0 \\rightarrow 6 \\gamma$. This requires a position-sensitive photon detector with high spatial granularity in $r$-, $\\varphi$-, and $z$-coordinates. The ECAL --- a barrel without end-caps located inside a magnetic field of 0.44 T --- consists of 18 identical concentric layers. Each layer of $1/3$ radiation length (X${_0}$) contains a converter plate followed by small cross-section high-gain tubes of 2640 mm active length which are sandwiched by passive pick-up strip plates. The ECAL, with a total of $6$ X${_0}$, has an energy resolution of $\\sigma (E)/E \\approx 13\\% / \\sqrt{E(\\mathrm{GeV})}$ and a position resolution of 4.5 mm for the shower foot. ...

  17. Materials for microfluidic chip fabrication.

    Science.gov (United States)

    Ren, Kangning; Zhou, Jianhua; Wu, Hongkai

    2013-11-19

    Through manipulating fluids using microfabricated channel and chamber structures, microfluidics is a powerful tool to realize high sensitive, high speed, high throughput, and low cost analysis. In addition, the method can establish a well-controlled microenivroment for manipulating fluids and particles. It also has rapid growing implementations in both sophisticated chemical/biological analysis and low-cost point-of-care assays. Some unique phenomena emerge at the micrometer scale. For example, reactions are completed in a shorter amount of time as the travel distances of mass and heat are relatively small; the flows are usually laminar; and the capillary effect becomes dominant owing to large surface-to-volume ratios. In the meantime, the surface properties of the device material are greatly amplified, which can lead to either unique functions or problems that we would not encounter at the macroscale. Also, each material inherently corresponds with specific microfabrication strategies and certain native properties of the device. Therefore, the material for making the device plays a dominating role in microfluidic technologies. In this Account, we address the evolution of materials used for fabricating microfluidic chips, and discuss the application-oriented pros and cons of different materials. This Account generally follows the order of the materials introduced to microfluidics. Glass and silicon, the first generation microfluidic device materials, are perfect for capillary electrophoresis and solvent-involved applications but expensive for microfabriaction. Elastomers enable low-cost rapid prototyping and high density integration of valves on chip, allowing complicated and parallel fluid manipulation and in-channel cell culture. Plastics, as competitive alternatives to elastomers, are also rapid and inexpensive to microfabricate. Their broad variety provides flexible choices for different needs. For example, some thermosets support in-situ fabrication of

  18. Rapid manufacturing for microfluidics

    CSIR Research Space (South Africa)

    Land, K

    2012-10-01

    Full Text Available for microfluidics K. LAND, S. HUGO, M MBANJWA, L FOURIE CSIR Materials Science and Manufacturing P O Box 395, Pretoria 0001, SOUTH AFRICA Email: kland@csir.co.za INTRODUCTION Microfluidics refers to the manipulation of very small volumes of fluid.... Microfluidics is at the forefront of developing solutions for drug discovery, diagnostics (from glucose tests to malaria and TB testing) and environmental diagnostics (E-coli monitoring of drinking water). In order to quickly implement new designs, a rapid...

  19. Commercialization of microfluidic devices.

    Science.gov (United States)

    Volpatti, Lisa R; Yetisen, Ali K

    2014-07-01

    Microfluidic devices offer automation and high-throughput screening, and operate at low volumes of consumables. Although microfluidics has the potential to reduce turnaround times and costs for analytical devices, particularly in medical, veterinary, and environmental sciences, this enabling technology has had limited diffusion into consumer products. This article analyzes the microfluidics market, identifies issues, and highlights successful commercialization strategies. Addressing niche markets and establishing compatibility with existing workflows will accelerate market penetration. Copyright © 2014 Elsevier Ltd. All rights reserved.

  20. Thermal dynamics of bomb calorimeters.

    Science.gov (United States)

    Lyon, Richard E

    2015-12-01

    The thermal dynamics of bomb calorimeters are modeled using a lumped heat transfer analysis in which heat is released in a pressure vessel/bomb immersed in a stirred water bath that is surrounded by a static air space bounded by an insulated (static) jacket, a constant/controlled temperature jacket (isoperibol), or a changing temperature (adiabatic) jacket. The temperature history of the water bath for each of these boundary conditions (methods) is well described by the two-term solution for the calorimeter response to a heat impulse (combustion), allowing the heat transfer coefficients and thermal capacities of the bomb and water bath to be determined parametrically. The validated heat transfer model provides an expression for direct calculation of the heat released in an arbitrary process inside a bomb calorimeter using the temperature history of the water bath for each of the boundary conditions (methods). This result makes possible the direct calculation of the heat of combustion of a sample in an isoperibol calorimeter from the recorded temperature history without the need for semi-empirical temperature corrections to account for non-adiabatic behavior. Another useful result is that the maximum temperature rise of the water bath in the static jacket method is proportional to the total heat generated, and the empirical proportionality constant, which is determined by calibration, accounts for all of the heat losses and thermal lags of the calorimeter.

  1. Tunable Microfluidic Dye Laser

    DEFF Research Database (Denmark)

    Olsen, Brian Bilenberg; Helbo, Bjarne; Kutter, Jörg Peter

    2003-01-01

    We present a tunable microfluidic dye laser fabricated in SU-8. The tunability is enabled by integrating a microfluidic diffusion mixer with an existing microfluidic dye laser design by Helbo et al. By controlling the relative flows in the mixer between a dye solution and a solvent......, the concentration of dye in the laser cavity can be adjusted, allowing the wavelength to be tuned. Wavelength tuning controlled by the dye concentration was demonstrated with macroscopic dye lasers already in 1971, but this principle only becomes practically applicable by the use of microfluidic mixing...

  2. CsI Calorimeter for a Compton-Pair Telescope

    Science.gov (United States)

    Grove, Eric J.

    We propose to build and test a hodoscopic CsI(Tl) scintillating-crystal calorimeter for a medium-energy γ-ray Compton and pair telescope. The design and technical approach for this calorimeter relies deeply on heritage from the Fermi LAT CsI Calorimeter, but it dramatically improves the low-energy performance of that design by reading out the scintillation light with silicon photomultipliers (SiPMs), making the technology developed for Fermi applicable in the Compton regime. While such a hodoscopic calorimeter is useful for an entire class of medium-energy γ-ray telescope designs, we propose to build it explicitly to support beam tests and balloon flight of the Proto-ComPair telescope, the development and construction of which was funded in a four-year APRA program beginning in 2015 ("ComPair: Steps to a Medium Energy γ-ray Mission" with PI J. McEnery of GSFC). That award did not include funding for its CsI calorimeter subsystem, and this proposal is intended to cover that gap. ComPair is a MIDEX-class instrument concept to perform a high-sensitivity survey of the γ-ray sky from 0.5 MeV to 500 MeV. ComPair is designed to provide a dramatic increase in sensitivity relative to previous instruments in this energy range (predominantly INTEGRAL/SPI and Compton COMPTEL), with the same transformative sensitivity increase - and corresponding scientific return- that the Fermi Large Area Telescope provided relative to Compton EGRET. To enable transformative science over a broad range of MeV energies and with a wide field of view, ComPair is a combined Compton telescope and pair telescope employing a silicon-strip tracker (for Compton scattering and pair conversion and tracking) and a solid-state CdZnTe calorimeter (for Compton absorption) and CsI calorimeter (for pair calorimetry), surrounded by a plastic scintillator anti-coincidence detector. Under the current proposal, we will complete the detailed design, assembly, and test of the CsI calorimeter for the risk

  3. The ATLAS Level-1 Calorimeter Trigger

    International Nuclear Information System (INIS)

    Achenbach, R; Andrei, V; Adragna, P; Apostologlou, P; Barnett, B M; Brawn, I P; Davis, A O; Edwards, J P; Asman, B; Bohm, C; Ay, C; Bauss, B; Bendel, M; Dahlhoff, A; Eckweiler, S; Booth, J R A; Thomas, P Bright; Charlton, D G; Collins, N J; Curtis, C J

    2008-01-01

    The ATLAS Level-1 Calorimeter Trigger uses reduced-granularity information from all the ATLAS calorimeters to search for high transverse-energy electrons, photons, τ leptons and jets, as well as high missing and total transverse energy. The calorimeter trigger electronics has a fixed latency of about 1 μs, using programmable custom-built digital electronics. This paper describes the Calorimeter Trigger hardware, as installed in the ATLAS electronics cavern

  4. The ATLAS Level-1 Calorimeter Trigger

    Energy Technology Data Exchange (ETDEWEB)

    Achenbach, R; Andrei, V [Kirchhoff-Institut fuer Physik, University of Heidelberg, D-69120 Heidelberg (Germany); Adragna, P [Physics Department, Queen Mary, University of London, London E1 4NS (United Kingdom); Apostologlou, P; Barnett, B M; Brawn, I P; Davis, A O; Edwards, J P [STFC Rutherford Appleton Laboratory, Harwell Science and Innovation Campus, Didcot, Oxon OX11 0QX (United Kingdom); Asman, B; Bohm, C [Fysikum, Stockholm University, SE-106 91 Stockholm (Sweden); Ay, C; Bauss, B; Bendel, M; Dahlhoff, A; Eckweiler, S [Institut fuer Physik, University of Mainz, D-55099 Mainz (Germany); Booth, J R A; Thomas, P Bright; Charlton, D G; Collins, N J; Curtis, C J [School of Physics and Astronomy, University of Birmingham, Birmingham B15 2TT (United Kingdom)], E-mail: e.eisenhandler@qmul.ac.uk (and others)

    2008-03-15

    The ATLAS Level-1 Calorimeter Trigger uses reduced-granularity information from all the ATLAS calorimeters to search for high transverse-energy electrons, photons, {tau} leptons and jets, as well as high missing and total transverse energy. The calorimeter trigger electronics has a fixed latency of about 1 {mu}s, using programmable custom-built digital electronics. This paper describes the Calorimeter Trigger hardware, as installed in the ATLAS electronics cavern.

  5. Fast and sensitive trace analysis of malachite green using a surface-enhanced Raman microfluidic sensor.

    Science.gov (United States)

    Lee, Sangyeop; Choi, Junghyun; Chen, Lingxin; Park, Byungchoon; Kyong, Jin Burm; Seong, Gi Hun; Choo, Jaebum; Lee, Yeonjung; Shin, Kyung-Hoon; Lee, Eun Kyu; Joo, Sang-Woo; Lee, Kyeong-Hee

    2007-05-08

    A rapid and highly sensitive trace analysis technique for determining malachite green (MG) in a polydimethylsiloxane (PDMS) microfluidic sensor was investigated using surface-enhanced Raman spectroscopy (SERS). A zigzag-shaped PDMS microfluidic channel was fabricated for efficient mixing between MG analytes and aggregated silver colloids. Under the optimal condition of flow velocity, MG molecules were effectively adsorbed onto silver nanoparticles while flowing along the upper and lower zigzag-shaped PDMS channel. A quantitative analysis of MG was performed based on the measured peak height at 1615 cm(-1) in its SERS spectrum. The limit of detection, using the SERS microfluidic sensor, was found to be below the 1-2 ppb level and this low detection limit is comparable to the result of the LC-Mass detection method. In the present study, we introduce a new conceptual detection technology, using a SERS microfluidic sensor, for the highly sensitive trace analysis of MG in water.

  6. The Prism Plastic Calorimeter (PPC)

    CERN Multimedia

    2002-01-01

    This proposal supports two goals: \\\\ \\\\ First goal:~~Demonstrate that current, widely used plastic technologies allow to design Prism Plastic Calorimeter~(PPC) towers with a new ``liquid crystal'' type plastic called Vectra. It will be shown that this technique meets the requirements for a LHC calorimeter with warm liquids: safety, hermeticity, hadronic compensation, resolution and time response. \\\\ \\\\ Second goal:~~Describe how one can design a warm liquid calorimeter integrated into a LHC detector and to list the advantages of the PPC: low price, minimum of mechanical structures, minimum of dead space, easiness of mechanical assembly, accessibility to the electronics, possibility to recirculate the liquid. The absorber and the electronic being outside of the liquid and easily accessible, one has maximum flexibility to define them. \\\\ \\\\ The R&D program, we define here aims at showing the feasibility of these new ideas by building nine towers of twenty gaps and exposing them to electron and hadron beams.

  7. The CHORUS calorimeter: test results

    International Nuclear Information System (INIS)

    Buontempo, S.; Capone, A.; Cocco, A.G.; De Pedis, D.; Di Capua, E.; Dore, U.; Ereditato, A.; Ferroni, M.; Fiorillo, G.; Loverre, P.F.; Luppi, C.; Macina, D.; Mazzoni, M.A.; Migliozzi, P.; Palladino, V.; Piredda, G.; Riccardi, F.; Righini, P.P.; Saitta, B.; Santacesaria, R.; Strolin, P.; Zucchelli, P.

    1995-01-01

    In the framework of the CHORUS experiment for the search of ν μ ν τ oscillations at CERN, we have built the high resolution calorimeter, intended for the measurement of the energy of hadronic showers produced in neutrino interactions. The calorimeter consists of three parts. The first two are made of lead and plastic scintillating fibers in the volume ratio 4 : 1, such as to achieve compensation. The third is a sandwich of lead plates and scintillator strips in the same volume ratio. The techniques used for the construction of the calorimeter are described, as well as its performance in shower and muon detection. We used electron, pion and muon beams in the energy range 2-100 GeV for this purpose. (orig.)

  8. Overview of the Calorimeter Readout Upgrades

    CERN Document Server

    Straessner, Arno; The ATLAS collaboration

    2018-01-01

    The ATLAS and CMS calorimeter electronics will be upgraded for the HL-LHC data taking phase to cope with higher event pile-up and to allow improved trigger strategies. This presentations gives an overview of the ongoing developments for the CMS barrel calorimeters and the ATLAS LAr and Tile calorimeters.

  9. Polystyrene calorimeter for electron beam dose measurements

    DEFF Research Database (Denmark)

    Miller, A.

    1995-01-01

    Calorimeters from polystrene have been constructed for dose measurement at 4-10 MeV electron accelerators. These calorimeters have been used successfully for a few years, and polystyrene calorimeters for use at energies down to 1 MeV and being tested. Advantage of polystyrene as the absorbing...

  10. Some possible improvements in scintillation calorimeters

    International Nuclear Information System (INIS)

    Lorenz, E.

    1985-03-01

    Two ideas for improvements of scintillation calorimeters will be presented: a) improved readout of scintillating, totally active electromagnetic calorimeters with combinations of silicon photodiodes and fluorescent panel collectors, b) use of time structure analysis on calorimetry, both for higher rate applications and improved resolution for hadron calorimeters. (orig.)

  11. Microfluidics for chemical processing

    NARCIS (Netherlands)

    Gardeniers, Johannes G.E.

    2006-01-01

    Microfluidic systems, and more specifically, microfluidic chips, have a number of features that make them particularly useful for the study of chemical reactions on-line. The present paper will discuss two examples, the study of fluidic behaviour at high pressures and the excitation and detection of

  12. The new ATLAS Fast Calorimeter Simulation

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00223142; The ATLAS collaboration

    2017-01-01

    Current and future need for large scale simulated samples motivate the development of reliable fast simulation techniques. The new Fast Calorimeter Simulation is an improved parameterized response of single particles in the ATLAS calorimeter that aims to accurately emulate the key features of the detailed calorimeter response as simulated with Geant4, yet approximately ten times faster. Principal component analysis and machine learning techniques are used to improve the performance and decrease the memory need compared to the current version of the ATLAS Fast Calorimeter Simulation. A prototype of this new Fast Calorimeter Simulation is in development and its integration into the ATLAS simulation infrastructure is ongoing.

  13. The new ATLAS Fast Calorimeter Simulation

    Science.gov (United States)

    Schaarschmidt, J.; ATLAS Collaboration

    2017-10-01

    Current and future need for large scale simulated samples motivate the development of reliable fast simulation techniques. The new Fast Calorimeter Simulation is an improved parameterized response of single particles in the ATLAS calorimeter that aims to accurately emulate the key features of the detailed calorimeter response as simulated with Geant4, yet approximately ten times faster. Principal component analysis and machine learning techniques are used to improve the performance and decrease the memory need compared to the current version of the ATLAS Fast Calorimeter Simulation. A prototype of this new Fast Calorimeter Simulation is in development and its integration into the ATLAS simulation infrastructure is ongoing.

  14. Software studies of GLD calorimeter

    Indian Academy of Sciences (India)

    a reconstruction code in a GEANT4-based simulator, and evaluate the performance with single π0's. In the GLD, an option for the hadron calorimeter, the so-called digital calorime- ter, is still under consideration. It has a huge number of small active cells, signals from which are read out as 1-bit digital value (or at most few ...

  15. COE1 Calorimeter Operations Manual

    Energy Technology Data Exchange (ETDEWEB)

    Santi, Peter Angelo [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-12-15

    The purpose of this manual is to describe the operations of the COE1 calorimeter which is used to measure the thermal power generated by the radioactive decay of plutonium-bearing materials for the purposes of assaying the amount of plutonium within the material.

  16. Concerning background from calorimeter ports

    International Nuclear Information System (INIS)

    Digiacomo, N.J.

    1985-01-01

    Any detector system viewing a port or slit in a calorimeter wall will see, in addition to the primary particles of interest, a background of charged and neutral particles and photons generated by scattering from the port walls and by leakage from incompletely contained primary particle showers in the calorimeter near the port. The signal to noise ratio attainable outside the port is a complex function of the primary source spectrum, the calorimeter and port design and, of course, the nature and acceptance of the detector system that views the port. Rather than making general statements about the overall suitability (or lack thereof) of calorimeter ports, we offer here a specific example based on the external spectrometer and slit of the NA34 experiment. This combination of slit and spectrometer is designed for fixed-target work, so that the primary particle momentum spectrum contains higher momentum particles than expected in a heavy ion colliding beam environment. The results are, nevertheless, quite relevant for the collider case

  17. Fast Calorimeter Simulation in ATLAS

    CERN Document Server

    Schaarschmidt, Jana; The ATLAS collaboration

    2017-01-01

    Producing the very large samples of simulated events required by many physics and performance studies with the ATLAS detector using the full GEANT4 detector simulation is highly CPU intensive. Fast simulation tools are a useful way of reducing CPU requirements when detailed detector simulations are not needed. During the LHC Run-1, a fast calorimeter simulation (FastCaloSim) was successfully used in ATLAS. FastCaloSim provides a simulation of the particle energy response at the calorimeter read-out cell level, taking into account the detailed particle shower shapes and the correlations between the energy depositions in the various calorimeter layers. It is interfaced to the standard ATLAS digitization and reconstruction software, and it can be tuned to data more easily than GEANT4. It is 500 times faster than full simulation in the calorimeter system. Now an improved version of FastCaloSim is in development, incorporating the experience with the version used during Run-1. The new FastCaloSim makes use of mach...

  18. ELECTRONICS FOR CALORIMETERS AT LHC

    International Nuclear Information System (INIS)

    Radeka, V.

    2001-01-01

    Some principal design features of front-end electronics for calorimeters in experiments at the LHC will be highlighted. Some concerns arising in the transition from the research and development and design phase to the construction will be discussed. Future challenges will be indicated

  19. Barrel calorimeter of the CMD-3 detector

    Energy Technology Data Exchange (ETDEWEB)

    Shebalin, V. E., E-mail: V.E.Shebalin@inp.nsk.su; Anisenkov, A. V.; Aulchenko, V. M.; Bashtovoy, N. S. [Russian Academy of Sciences, Budker Institute of Nuclear Physics, Siberian Branch (Russian Federation); Epifanov, D. A. [University of Tokyo, Department of Physics (Japan); Epshteyn, L. B.; Grebenuk, A. A.; Ignatov, F. V.; Erofeev, A. L.; Kovalenko, O. A.; Kozyrev, A. N.; Kuzmin, A. S.; Logashenko, I. B.; Mikhailov, K. Yu.; Razuvaev, G. P.; Ruban, A. A.; Shwartz, B. A.; Talyshev, A. A.; Titov, V. M.; Yudin, Yu. V. [Russian Academy of Sciences, Budker Institute of Nuclear Physics, Siberian Branch (Russian Federation)

    2015-12-15

    The structure of the barrel calorimeter of the CMD-3 detector is presented in this work. The procedure of energy calibration of the calorimeter and the method of photon energy restoration are described. The distinctive feature of this barrel calorimeter is its combined structure; it is composed of two coaxial subsystems: a liquid xenon calorimeter and a crystalline CsI calorimeter. The calorimeter spatial resolution of the photon conversion point is about 2 mm, which corresponds to an angular resolution of ∼6 mrad. The energy resolution of the calorimeter is about 8% for photons with energy of 200 MeV and 4% for photons with energy of 1 GeV.

  20. An instant dose obtainable in situ calorimeter

    International Nuclear Information System (INIS)

    Kubo, H.; Mento, D.

    1984-01-01

    The development of a computer-linked water calorimeter is described. The advantages of this system are twofold: (i) instant dose determination is possible; and (ii) the calorimeter operation is much simpler than conventional null balance techniques. The entire calorimeter measurement procedure from the set-up to the dose determination for 10 runs was finished in approximately 2 1/2 h. A smaller calorimeter which could be kept in the treatment room for equilibrium, should permit further reduction of the time. The use of a smaller, portable computer would allow local data taking and analysis, eliminating the need for modems, phone lines and long cables. This would lead to a completely self-contained set-up at the treatment room. Although the technique is described for a polystyrene-water calorimeter, it should be equally applicable for a water calorimeter as well as a conventional isolated calorimeter. (author)

  1. Barrel calorimeter of the CMD-3 detector

    International Nuclear Information System (INIS)

    Shebalin, V. E.; Anisenkov, A. V.; Aulchenko, V. M.; Bashtovoy, N. S.; Epifanov, D. A.; Epshteyn, L. B.; Grebenuk, A. A.; Ignatov, F. V.; Erofeev, A. L.; Kovalenko, O. A.; Kozyrev, A. N.; Kuzmin, A. S.; Logashenko, I. B.; Mikhailov, K. Yu.; Razuvaev, G. P.; Ruban, A. A.; Shwartz, B. A.; Talyshev, A. A.; Titov, V. M.; Yudin, Yu. V.

    2015-01-01

    The structure of the barrel calorimeter of the CMD-3 detector is presented in this work. The procedure of energy calibration of the calorimeter and the method of photon energy restoration are described. The distinctive feature of this barrel calorimeter is its combined structure; it is composed of two coaxial subsystems: a liquid xenon calorimeter and a crystalline CsI calorimeter. The calorimeter spatial resolution of the photon conversion point is about 2 mm, which corresponds to an angular resolution of ∼6 mrad. The energy resolution of the calorimeter is about 8% for photons with energy of 200 MeV and 4% for photons with energy of 1 GeV

  2. Meta-atom microfluidic sensor for measurement of dielectric properties of liquids

    Science.gov (United States)

    Awang, Robiatun A.; Tovar-Lopez, Francisco J.; Baum, Thomas; Sriram, Sharath; Rowe, Wayne S. T.

    2017-03-01

    High sensitivity microwave frequency microfluidic sensing is gaining popularity in chemical and biosensing applications for evaluating the dielectric properties of liquid samples. Here, we show that a tiny microfluidic channel positioned in the gaps of a dual-gap meta-atom split-ring resonator can exploit the electric field sensitivity to predict the dielectric properties of liquid samples. Employing an empirical relation between resonant characteristics of the fabricated sensor and the complex permittivity of water-ethanol or water-methanol mixtures produces good congruence to standardized values from the literature. This microfluidic sensor offers a potential lab-on-chip solution for liquid dielectric characterization without external electrical connections.

  3. Development of a highly sensitive lithium fluoride thermoluminescence dosimeter

    International Nuclear Information System (INIS)

    Moraes da Silva, Teresinha de; Campos, Leticia Lucente

    1995-01-01

    In recent times, LiF: Mg, Cu, P thermoluminescent phosphor has been increasingly in use for radiation monitoring due its high sensitivity and ease of preparation. The Dosimetric Materials Production Laboratory of IPEN, (Nuclear Energy Institute) has developed a simple method to obtain high sensitivity LiF. The preparation method is described. (author). 4 refs., 1 fig., 1 tab

  4. Electrochemistry-based approaches to low cost, high sensitivity, automated, multiplexed protein immunoassays for cancer diagnostics.

    Science.gov (United States)

    Dixit, Chandra K; Kadimisetty, Karteek; Otieno, Brunah A; Tang, Chi; Malla, Spundana; Krause, Colleen E; Rusling, James F

    2016-01-21

    Early detection and reliable diagnostics are keys to effectively design cancer therapies with better prognoses. The simultaneous detection of panels of biomarker proteins holds great promise as a general tool for reliable cancer diagnostics. A major challenge in designing such a panel is to decide upon a coherent group of biomarkers which have higher specificity for a given type of cancer. The second big challenge is to develop test devices to measure these biomarkers quantitatively with high sensitivity and specificity, such that there are no interferences from the complex serum or tissue matrices. Lastly, integrating all these tests into a technology that does not require exclusive training to operate, and can be used at point-of-care (POC) is another potential bottleneck in futuristic cancer diagnostics. In this article, we review electrochemistry-based tools and technologies developed and/or used in our laboratories to construct low-cost microfluidic protein arrays for the highly sensitive detection of a panel of cancer-specific biomarkers with high specificity which at the same time has the potential to be translated into POC applications.

  5. ''Massless gaps'' for solenoid + calorimeter

    International Nuclear Information System (INIS)

    Marraffino, J.; Wu, W.; Beretvas, A.; Green, D.; Denisenko, K.; Para, A.

    1991-11-01

    The necessary existence of material in front of the first active element in a calorimeter will degrade the performance of that device. The question is by what factor. The follow up question is what can be done to minimize the damage. These questions are usually of primary importance for liquid argon calorimetry because of the necessity of containment dewars. However, the problem is universal. For example, the Solenoid Detector Collaboration, SDC, has proposed a superconducting coil which would be placed in front of the EM calorimeter. Although much effort has been made to minimize the depth of material in the coil, still the resolution and linearity must be optimized if the SDC goal of precision electromagnetic (EM) calorimetry is to be realized

  6. Electromagnetic calorimeter on liquid krypton

    International Nuclear Information System (INIS)

    Bazzotti, M.; Bianco, G.L.; Lanni, F.; Maggi, B.; Palombo, F.; Sala, A.

    1990-01-01

    This paper reports on use of noble condensed gases as calorimeter media that is attractive due to the possibility to get not only good energy resolution (like in NaI and CsI calorimeters) but better space resolution for photons. Longitudinal segmentation can provide information for particle identification by dE/dx and also e/π-separation based on longitudinal structure of the shower. The best material for this aim is of course liquid Zenon, but it is impossible to get the necessary amount of it in reasonable time. Therefore, the authors have stopped their choice on the next candidate-liquid Krypton (LKr). Its sufficient amount can be obtained before to the beginning of the experiment

  7. Cell manipulation in microfluidics

    International Nuclear Information System (INIS)

    Yun, Hoyoung; Kim, Kisoo; Lee, Won Gu

    2013-01-01

    Recent advances in the lab-on-a-chip field in association with nano/microfluidics have been made for new applications and functionalities to the fields of molecular biology, genetic analysis and proteomics, enabling the expansion of the cell biology field. Specifically, microfluidics has provided promising tools for enhancing cell biological research, since it has the ability to precisely control the cellular environment, to easily mimic heterogeneous cellular environment by multiplexing, and to analyze sub-cellular information by high-contents screening assays at the single-cell level. Various cell manipulation techniques in microfluidics have been developed in accordance with specific objectives and applications. In this review, we examine the latest achievements of cell manipulation techniques in microfluidics by categorizing externally applied forces for manipulation: (i) optical, (ii) magnetic, (iii) electrical, (iv) mechanical and (v) other manipulations. We furthermore focus on history where the manipulation techniques originate and also discuss future perspectives with key examples where available. (topical review)

  8. Microfluidic chemical reaction circuits

    Science.gov (United States)

    Lee, Chung-cheng [Irvine, CA; Sui, Guodong [Los Angeles, CA; Elizarov, Arkadij [Valley Village, CA; Kolb, Hartmuth C [Playa del Rey, CA; Huang, Jiang [San Jose, CA; Heath, James R [South Pasadena, CA; Phelps, Michael E [Los Angeles, CA; Quake, Stephen R [Stanford, CA; Tseng, Hsian-rong [Los Angeles, CA; Wyatt, Paul [Tipperary, IE; Daridon, Antoine [Mont-Sur-Rolle, CH

    2012-06-26

    New microfluidic devices, useful for carrying out chemical reactions, are provided. The devices are adapted for on-chip solvent exchange, chemical processes requiring multiple chemical reactions, and rapid concentration of reagents.

  9. Next Generation CALICE Electromagnetic Calorimeter

    OpenAIRE

    Grondin, Denis; Jeans, Daniel

    2010-01-01

    This paper presents mechanical R&D for the CALICE Silicon-tungsten electromagnetic calorimeter. After the physics ECAL prototype, tested in 2006 (DESY-CERN), 2007 (CERN), 2008 (FNAL) and before the design of different 'modules 0' (barrel and endcap) for a final detector, a technological ECAL prototype, called the EUDET module, is under design in order to have a close to full scale technological solution which could be used for the final detector, taking into account future industrialisation o...

  10. Next Generation CALICE Electromagnetic Calorimeter

    OpenAIRE

    Grondin, Denis; Jeans, Daniel

    2010-01-01

    This paper presents mechanical R&D for the CALICE Silicon-tungsten electromagnetic calorimeter. After the physics ECAL prototype, tested in 2006 (DESY-CERN), 2007 (CERN), 2008 (FNAL) and before the design of different "modules 0" (barrel and endcap) for a final detector, a technological ECAL prototype, called the EUDET module, is under design in order to have a close to full scale technological solution which could be used for the final detector, taking into account future industrialisation o...

  11. The KLOE fiber electromagnetic calorimeter

    International Nuclear Information System (INIS)

    Incagli, Marco

    1998-01-01

    The construction and equipment of the KLOE electromagnetic calorimeter has ended in March 1997. In parallel to the construction, all modules have been tested at the Cosmic Ray Test Stand (CRTS) facility, in Frascati National Laboratories (Rome). The construction technique, based on scintillating fibers alternated to very thin (0.5 mm) grooved lead planes, is described and the main results both from the CRTS and from a preliminary Test Beam with low energy electrons and muons are reported in this note

  12. The T.M. Calorimeter

    International Nuclear Information System (INIS)

    Mas, P.; Goer, J. de

    1970-01-01

    The T.M. calorimeter is the isothermal type. It consists only of a sample of graphite and a jacket of stainless steel filled with nitrogen. The chromel-alumel thermocouples which measure the temperature difference between the sample and the jacket also serve to suspend the sample. The jacket is kept at a constant temperature: i.e. that of the water in the swimming pool

  13. Electromagnetic Calorimeter for HADES Experiment

    Directory of Open Access Journals (Sweden)

    Rodríguez-Ramos P.

    2014-01-01

    Full Text Available Electromagnetic calorimeter (ECAL is being developed to complement dilepton spectrometer HADES. ECAL will enable the HADES@FAIR experiment to measure data on neutral meson production in heavy ion collisions at the energy range of 2-10 AGeV on the beam of future accelerator SIS100@FAIR. We will report results of the last beam test with quasi-monoenergetic photons carried out in MAMI facility at Johannes Gutenberg Universität Mainz.

  14. Performance of the ATLAS Tile Calorimeter

    CERN Document Server

    Heelan, Louise; The ATLAS collaboration

    2015-01-01

    The ATLAS Tile hadronic calorimeter (TileCal) provides highly-segmented energy measurements of incoming particles. It is a key detector for the measurement of hadrons, jets, tau leptons and missing transverse energy. It is also useful for identification and reconstruction of muons due to good signal to noise ratio. The calorimeter consists of thin steel plates and 460,000 scintillating tiles configured into 5000 cells, each viewed by two photomultipliers. The calorimeter response and its readout electronics is monitored to better than 1% using radioactive source, laser and charge injection systems. The calibration and performance of the calorimeter have been established through test beam measurements, cosmic ray muons and the large sample of proton-proton collisions acquired in 2011 and 2012. Results on the calorimeter performance are presented, including the absolute energy scale, timing, noise and associated stabilities. The results demonstrate that the Tile Calorimeter has performed well within the design ...

  15. Upgrading ATLAS Fast Calorimeter Simulation

    CERN Document Server

    Heath, Matthew Peter; The ATLAS collaboration

    2017-01-01

    Producing the very large samples of simulated events required by many physics and performance studies with the ATLAS detector using the full GEANT4 detector simulation is highly CPU intensive. Fast simulation tools are a useful way of reducing CPU requirements when detailed detector simulations are not needed. During the LHC Run-1, a fast calorimeter simulation (FastCaloSim) was successfully used in ATLAS. FastCaloSim provides a simulation of the particle energy response at the calorimeter read-out cell level, taking into account the detailed particle shower shapes and the correlations between the energy depositions in the various calorimeter layers. It is interfaced to the standard ATLAS digitization and reconstruction software, and it can be tuned to data more easily than Geant4. Now an improved version of FastCaloSim is in development, incorporating the experience with the version used during Run-1. The new FastCaloSim aims to overcome some limitations of the first version by improving the description of s...

  16. Central hadron calorimeter of UA1

    International Nuclear Information System (INIS)

    Corden, M.J.; Dowell, J.D.; Edwards, M.J.

    1983-12-01

    An iron-scintillator sampling calorimeter is described, which measures hadronic energy in proton-antiproton interactions at the CERN 540 GeV SPS collider. Construction details are given of the instrumentation of the magnet pieces of the UA1 experiment and of the methods used to measure the calorimeter response and resolution. The system of lasers and quartz fibres, which allows long term monitoring of the calorimeter response, is also described. (author)

  17. Rugged calorimeter with a fast rise time

    International Nuclear Information System (INIS)

    McMurtry, W.M.; Dolce, S.R.

    1980-01-01

    An intrinsic 1-mil-thick gold foil calorimeter has been developed which rises to 95% of the energy deposited in less than 2 microseconds. This calorimeter is very rugged, and can withstand rough handling without damage. The time constant is long, in the millisecond range, because of its unique construction. Use of this calorimeter has produced 100% data recovery, and agreement with true deposition to less than 10%

  18. Central hadron calorimeter of UA1

    International Nuclear Information System (INIS)

    Corden, M.J.; Dowell, J.D.; Edwards, M.J.; Ellis, N.N.; Garvey, J.; Grant, D.; Homer, R.J.; Kenyon, I.R.; McMahon, T.J.; Schanz, G.; Sumorok, K.C.T.O.; Watkins, P.M.; Wilson, J.A.; Barnes, G.; Bowcock, T.J.V.; Eisenhandler, E.; Gibson, W.R.; Honma, A.K.; Kalmus, P.I.P.; Keeler, R.K.; Pritchard, T.W.; Salvi, G.A.P.; Thompson, G.; Arnison, G.T.J.; Astbury, A.; Cash, A.R.; Grayer, G.H.; Haynes, W.J.; Hill, D.L.; Moore, D.R.; Nandi, A.K.; Percival, M.D.; Roberts, J.H.C.; Scott, W.G.; Shah, T.P.; Stanhope, R.J.; White, D.E.A.

    1985-01-01

    An iron-scintillator sampling calorimeter is described, which measures hadronic energy in proton-antiproton interactions at the CERN 540 GeV SPS collider. Construction details are given of the instrumentation of the magnet pieces of the UA1 experiment and of the methods used to measure the calorimeter response and resolution. The system of lasers and quartz fibres, which allows long term monitoring of the calorimeter response, is also described. (orig.)

  19. Signal processing for liquid ionization calorimeters

    International Nuclear Information System (INIS)

    Cleland, W.E.; Stern, E.G.

    1992-01-01

    We present the results of a study of the effects of thermal and pileup noise in liquid ionization calorimeters operating in a high luminosity calorimeters operating in a high luminosity environment. The method of optimal filtering of multiply-sampled signals which may be used to improve the timing and amplitude resolution of calorimeter signals is described, and its implications for signal shaping functions are examined. The dependence of the time and amplitude resolution on the relative strength of the pileup and thermal noise, which varies with such parameters as luminosity, rapidity and calorimeter cell size, is examined

  20. Family reunion for the UA2 calorimeter

    CERN Multimedia

    Abha Eli Phoboo

    2015-01-01

    After many years in CERN’s Microcosm exhibition, the last surviving UA2 central calorimeter module has been moved to Hall 175, the technical development laboratory of the ATLAS Tile Hadronic Calorimeter (Tilecal). The UA2 and ATLAS calorimeters are cousins, as both were designed by Otto Gildemeister. Now side by side, the calorimeters illustrate the progress made in sampling organic scintillator calorimeters over the past 35 years.   The ATLAS Tile Calorimeter prototypes (left) and the UA2 central calorimeter (right) in Hall 175. (Image: Mario Campanelli/ATLAS.) From 1981 to 1990, the UA2 experiment was one of the two detectors on CERN’s flagship accelerator, the SPS. At the heart of the UA2 detector was the central calorimeter. It was made up of 24 slices – each weighing four tonnes – arranged like orange segments around the collision point. These calorimeter slices played a central role in the research carried out by UA2 for the discovery of W bosons...

  1. Secondary Emission Calorimeter Sensor Development

    Science.gov (United States)

    Winn, David R.; Onel, Yasar

    2012-12-01

    In a Secondary Emission electron(SEe) detector module, Secondary Emission electrons (SEe) are generated from an SE surface/cathode, when charged hadronic or electromagnetic particles, particularly shower particles, penetrate an SE sampling module placed between absorber materials (Fe, Cu, Pb, W etc) in calorimeters. The SE cathode is a thin (10-50 nm thick) film (simple metal-oxides, or other higher yield materials) on the surface of a metal plate, which serves as the entrance “window” to a compact vacuum vessel (metal or metal-ceramic); this SE film cathode is analogous to a photocathode, and the SEe are similar to p.e., which are then amplified by dynodes, also is in a PMT. SE sensor modules can make use of electrochemically etched/machined or laser-cut metal mesh dynode sheets, as large as ~30 cm square, to amplify the Secondary Emission Electrons (SEe), much like those that compact metal mesh or mesh dynode PMT's use to amplify p.e.'s. The construction requirements easier than a PMT, since the entire final assembly can be done in air; there are no critical controlled thin film depositions, cesiation or other oxygen-excluded processes or other required vacuum activation, and consequently bake-out can be a refractory temperatures; the module is sealed by normal vacuum techniques (welding or brazing or other high temperature joinings), with a simple final heated vacuum pump-out and tip-off. The modules envisioned are compact, high gain, high speed, exceptionally radiation damage resistant, rugged, and cost effective, and can be fabricated in arbitrary tileable shapes. The SE sensor module anodes can be segmented transversely to sizes appropriate to reconstruct electromagnetic cores with high precision. The GEANT4 and existing calorimeter data estimated calorimeter response performance is between 35-50 Secondary Emission electrons per GeV, in a 1 cm thick Cu absorber calorimeter, with a gain per SEe > 105 per SEe, and an e/pi<1.2. The calorimeter pulse width is

  2. The ATLAS Liquid Argon Calorimeters: integration, installation and commissioning

    International Nuclear Information System (INIS)

    Tikhonov, Yu.

    2008-01-01

    The ATLAS liquid argon calorimeter system consists of an electromagnetic barrel calorimeter and two end-caps with electromagnetic, hadronic and forward calorimeters positioned in three cryostats. Since May 2006 the LAr barrel calorimeter records regular calibration runs and takes cosmic muon data together with tile hadronic calorimeter in the ATLAS cavern. The cosmic runs with end-cap calorimeters started in April 2007. First results of these combined runs are presented

  3. A high-sensitivity neutron counter and waste-drum counting with the high-sensitivity neutron instrument

    International Nuclear Information System (INIS)

    Hankins, D.E.; Thorngate, J.H.

    1993-04-01

    At Lawrence Livermore National Laboratory (LLNL), a highly sensitive neutron counter was developed that can detect and accurately measure the neutrons from small quantities of plutonium or from other low-level neutron sources. This neutron counter was originally designed to survey waste containers leaving the Plutonium Facility. However, it has proven to be useful in other research applications requiring a high-sensitivity neutron instrument

  4. Controlled growth of silica-titania hybrid functional nanoparticles through a multistep microfluidic approach.

    Science.gov (United States)

    Shiba, K; Sugiyama, T; Takei, T; Yoshikawa, G

    2015-11-11

    Silica/titania-based functional nanoparticles were prepared through controlled nucleation of titania and subsequent encapsulation by silica through a multistep microfluidic approach, which was successfully applied to obtaining aminopropyl-functionalized silica/titania nanoparticles for a highly sensitive humidity sensor.

  5. Status of the ATLAS hadronic tile calorimeter

    International Nuclear Information System (INIS)

    Leitner, R.

    2005-01-01

    Short status of the Tile Calorimeter project is given. Major achievements in the mechanical construction of the detector modules, their instrumentation, cylinders assembly, as well as the principles of the detector front-end electronics, are described. The ideas of Tile Calorimeter module calibration are presented

  6. An overview of CMS central hadron calorimeter

    CERN Document Server

    Katta, S

    2002-01-01

    The central hadron calorimeter for CMS detector is a sampling calorimeter with active medium as scintillator plates interleaved with brass absorber plates. It covers the central pseudorapidity region (¿ eta ¿<3.0). The design and construction aspects are reported. The status of construction and assembly of various subdetectors of HCAL are presented. (5 refs).

  7. Cone calorimeter tests of wood composites

    Science.gov (United States)

    Robert H. White; Kuma Sumathipala

    2013-01-01

    The cone calorimeter is widely used for the determination of the heat release rate (HRR) of building products and other materials. As part of an effort to increase the availability of cone calorimeter data on wood products, the U.S. Forest Products Laboratory and the American Wood Council conducted this study on composite wood products in cooperation with the Composite...

  8. Mounting LHCb hadron calorimeter scintillating tiles

    CERN Multimedia

    Maximilien Brice

    2004-01-01

    Scintillating tiles are carefully mounted in the hadronic calorimeter for the LHCb detector. These calorimeters measure the energy of particles that interact via the strong force, called hadrons. The detectors are made in a sandwich-like structure where these scintillator tiles are placed between metal sheets.

  9. Assembly of the CMS hadronic calorimeter

    CERN Multimedia

    Maximilien Brice

    2004-01-01

    The hadronic calorimeter is assembled on the end-cap of the CMS detector in the assembly hall. Hadronic calorimeters measure the energy of particles that interact via the strong force, called hadrons. The detectors are made in a sandwich-like structure where these scintillator tiles are placed between metal sheets.

  10. The Scintillator Tile Hadronic Calorimeter Prototype

    International Nuclear Information System (INIS)

    Rusinov, V.

    2006-01-01

    A high granularity scintillator hadronic calorimeter prototype is described. The calorimeter is based on a novel photodetector - Silicon Photo-Multiplier (SiPM). The main parameters of SiPM are discussed as well as readout cell construction and optimization. The experience with a small prototype production and testing is described. A new 8 k channel prototype is being manufactured now

  11. Several versions of forward gas ionization calorimeter

    International Nuclear Information System (INIS)

    Babintsev, V.V.; Kholodenko, A.G.; Rodnov, Yu.V.

    1994-01-01

    The properties of several versions of a gas ionization calorimeter are analyzed by means of the simulation with the GEANT code. The jet energy and coordinate resolutions are evaluated. Some versions of the forward calorimeter meet the ATLAS requirements. 13 refs., 15 figs., 7 tabs

  12. LHCb: Physics with the LHCb calorimeter

    CERN Multimedia

    Barsuk, S

    2007-01-01

    The LHCb calorimeter comprises the scintillator pad detector (SPD), preshower (PS), electromagnetic Shashlyk type (ECAL) and hadronichadronic Tile (HCAL) calorimeters, arranged in pseudo-projective geometry. All the four detectors follow the general principle of reading the light from scintillator tiles with wave length shifting fibers, and transporting the light towards photomultipliers (25 ns R/O).

  13. Calorimeter triggers for hard collisions

    International Nuclear Information System (INIS)

    Landshoff, P.V.; Polkinghorne, J.C.

    1978-01-01

    We discuss the use of a forward calorimeter to trigger on hard hadron-hadron collisions. We give a derivation in the covariant parton model of the Ochs-Stodolsky scaling law for single-hard-scattering processes, and investigate the conditions when instead a multiple- scattering mechanism might dominate. With a proton beam, this mechanism results in six transverse jets, with a total average multiplicity about twice that seen in ordinary events. We estimate that its cross section is likely to be experimentally accessible at avalues of the beam energy in the region of 100 GeV/c

  14. The STAR endcap electromagnetic calorimeter

    International Nuclear Information System (INIS)

    Allgower, C.E.; Anderson, B.D.; Baldwin, A.R.; Balewski, J.; Belt-Tonjes, M.; Bland, L.C.; Brown, R.L.; Cadman, R.V.; Christie, W.; Cyliax, I.; Dunin, V.; Efimov, L.; Eppley, G.; Gagliardi, C.A.; Gagunashvili, N.; Hallman, T.; Hunt, W.; Jacobs, W.W.; Klyachko, A.; Krueger, K.; Kulikov, A.; Ogawa, A.; Panebratsev, Y.; Planinic, M.; Puskar-Pasewicz, J.; Rakness, G.; Razin, S.; Rogachevski, O.; Shimansky, S.; Solberg, K.A.; Sowinski, J.; Spinka, H.; Stephenson, E.J.; Tikhomirov, V.; Tokarev, M.; Tribble, R.E.; Underwood, D.; Vander Molen, A.M.; Vigdor, S.E.; Watson, J.W.; Westfall, G.; Wissink, S.W.; Yokosawa, A.; Yurevich, V.; Zhang, W.-M.; Zubarev, A.

    2003-01-01

    The STAR endcap electromagnetic calorimeter will provide full azimuthal coverage for high-p T photons, electrons and electromagnetically decaying mesons over the pseudorapidity range 1.086≤η≤2.00. It includes a scintillating-strip shower-maximum detector to provide π 0 /γ discrimination and preshower and postshower layers to aid in distinguishing between electrons and charged hadrons. The triggering capabilities and coverage it offers are crucial for much of the spin physics program to be carried out in polarized proton-proton collisions

  15. The STAR endcap electromagnetic calorimeter

    Energy Technology Data Exchange (ETDEWEB)

    Allgower, C.E.; Anderson, B.D.; Baldwin, A.R.; Balewski, J.; Belt-Tonjes, M.; Bland, L.C.; Brown, R.L.; Cadman, R.V.; Christie, W.; Cyliax, I.; Dunin, V.; Efimov, L.; Eppley, G.; Gagliardi, C.A.; Gagunashvili, N.; Hallman, T.; Hunt, W.; Jacobs, W.W.; Klyachko, A.; Krueger, K.; Kulikov, A.; Ogawa, A.; Panebratsev, Y.; Planinic, M.; Puskar-Pasewicz, J.; Rakness, G.; Razin, S.; Rogachevski, O.; Shimansky, S.; Solberg, K.A.; Sowinski, J.; Spinka, H.; Stephenson, E.J.; Tikhomirov, V.; Tokarev, M.; Tribble, R.E.; Underwood, D.; Vander Molen, A.M.; Vigdor, S.E. E-mail: vigdor@iucf.indiana.edu; Watson, J.W.; Westfall, G.; Wissink, S.W.; Yokosawa, A.; Yurevich, V.; Zhang, W.-M.; Zubarev, A

    2003-03-01

    The STAR endcap electromagnetic calorimeter will provide full azimuthal coverage for high-p{sub T} photons, electrons and electromagnetically decaying mesons over the pseudorapidity range 1.086{<=}{eta}{<=}2.00. It includes a scintillating-strip shower-maximum detector to provide {pi}{sup 0}/{gamma} discrimination and preshower and postshower layers to aid in distinguishing between electrons and charged hadrons. The triggering capabilities and coverage it offers are crucial for much of the spin physics program to be carried out in polarized proton-proton collisions.

  16. ATLAS Tile calorimeter calibration and monitoring systems

    CERN Document Server

    Cortes-Gonzalez, Arely; The ATLAS collaboration

    2017-01-01

    The ATLAS Tile Calorimeter is the central section of the hadronic calorimeter of the ATLAS experiment and provides important information for reconstruction of hadrons, jets, hadronic decays of tau leptons and missing transverse energy. This sampling calorimeter uses steel plates as absorber and scintillating tiles as active medium. The light produced by the passage of charged particles is transmitted by wavelength shifting fibres to photomultiplier tubes, located in the outer part of the calorimeter. The readout is segmented into about 5000 cells (longitudinally and transversally), each of them being read out by two photomultiplier in parallel. To calibrate and monitor the stability and performance of each part of the readout chain during the data taking, a set of calibration systems is used. The calibration system comprises Cesium radioactive sources, laser, charge injection elements and an integrator based readout system. Combined information from all systems allows to monitor and equalise the calorimeter r...

  17. Upgrading the Fast Calorimeter Simulation in ATLAS

    CERN Document Server

    Schaarschmidt, Jana; The ATLAS collaboration

    2017-01-01

    The tremendous need for simulated samples now and even more so in the future, encourage the development of fast simulation techniques. The Fast Calorimeter Simulation is a faster though less accurate alternative to the full calorimeter simulation with Geant4. It is based on parametrizing the longitudunal and lateral energy deposits of single particles in the ATLAS calorimeter. Principal component analysis and machine learning techniques are used to improve the performance and decrease the memory need compared to the current version of the ATLAS Fast Calorimeter Simulation. The parametrizations are expanded to cover very high energies and very forward detector regions, to increase the applicability of the tool. A prototype of this upgraded Fast Calorimeter Simulation has been developed and first validations with single particles show substantial improvements over the previous version.

  18. ATLAS Tile calorimeter calibration and monitoring systems

    CERN Document Server

    Marjanovic, Marija; The ATLAS collaboration

    2018-01-01

    The ATLAS Tile Calorimeter (TileCal) is the central section of the hadronic calorimeter of the ATLAS experiment. This sampling calorimeter uses steel plates as absorber and scintillating tiles as active medium. The light produced by the passage of charged particles is transmitted by wavelength shifting fibers to photo-multiplier tubes (PMTs), located in the outer part of the calorimeter. The readout is segmented into about 5000 cells, each one being read out by two PMTs in parallel. To calibrate and monitor the stability and performance of the full readout chain during the data taking, a set of calibration sub-systems is used. The TileCal calibration system comprises Cesium radioactive sources, laser, charge injection elements, and an integrator based readout system. Combined information from all systems allows to monitor and to equalize the calorimeter response at each stage of the signal evolution, from scintillation light to digitization. Calibration runs are monitored from a data quality perspective and u...

  19. The large hadron collider beauty experiment calorimeters

    International Nuclear Information System (INIS)

    Martens, A.; LHCb Collaboration; Martens, A.

    2010-01-01

    The Large Hadron Collider beauty experiment (LHCb), one of the four largest experiments at the LHC at CERN, is dedicated to precision studies of CP violation and other rare effects, in particular in the b and c quark sectors. It aims at precisely measuring the Standard Model parameters and searching for effects inconsistent with this picture. The LHCb calorimeter system comprises a scintillating pad detector, a pre-shower (PS), electromagnetic (ECAL) and hadronic calorimeters, all of these employing the principle of transporting the light from scintillating layers with wavelength shifting fibers to photomultipliers. The fast response of the calorimeters ensures their key role in the LHCb trigger, which has to cope with the LHC collision rate of 40MHz. After discussing the design and expected performance of the LHCb calorimeter system, one addresses the time and energy calibration issues. The results obtained with the calorimeter system from the first LHC data will be shown.

  20. ATLAS Tile calorimeter calibration and monitoring systems

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00445232; The ATLAS collaboration

    2016-01-01

    The ATLAS Tile Calorimeter (TileCal) is the central section of the hadronic calorimeter of the ATLAS experiment and provides important information for reconstruction of hadrons, jets, hadronic decays of tau leptons and missing transverse energy. This sampling calorimeter uses steel plates as absorber and scintillating tiles as active medium. The light produced by the passage of charged particles is transmitted by wavelength shifting fibres to photomultiplier tubes (PMTs), located on the outside of the calorimeter. The readout is segmented into about 5000 cells (longitudinally and transversally), each of them being read out by two PMTs in parallel. To calibrate and monitor the stability and performance of each part of the readout chain during the data taking, a set of calibration systems is used. The TileCal calibration system comprises Cesium radioactive sources, laser and charge injection elements and it allows to monitor and equalize the calorimeter response at each stage of the signal production, from scin...

  1. ATLAS Tile calorimeter calibration and monitoring systems

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00445232; The ATLAS collaboration

    2017-01-01

    The ATLAS Tile Calorimeter (TileCal) is the central section of the hadronic calorimeter of the ATLAS experiment and provides important information for reconstruction of hadrons, jets, hadronic decays of tau leptons and missing transverse energy. This sampling calorimeter uses steel plates as absorber and scintillating tiles as active medium. The light produced by the passage of charged particles is transmitted by wavelength shifting fibres to photomultiplier tubes (PMTs), located on the outside of the calorimeter. The readout is segmented into about 5000 cells (longitudinally and transversally), each of them being read out by two PMTs in parallel. To calibrate and monitor the stability and performance of each part of the readout chain during the data taking, a set of calibration systems is used. The TileCal calibration system comprises cesium radioactive sources, Laser and charge injection elements, and allows for monitoring and equalization of the calorimeter response at each stage of the signal production, ...

  2. Readout Electronics for the ATLAS LAr Calorimeter at HL-LHC

    CERN Document Server

    Chen, H; The ATLAS collaboration

    2011-01-01

    The ATLAS experiment is one of the two general-purpose detectors designed to study proton-proton collisions (14 TeV in the center of mass) produced at the Large Hadron Collider (LHC) and to explore the full physics potential of the LHC machine at CERN. The ATLAS Liquid Argon (LAr) calorimeters are high precision, high sensitivity and high granularity detectors designed to provide precision measurements of electrons, photons, jets and missing transverse energy. ATLAS (and its LAr Calorimeters) has been operating and collecting p-p collisions at LHC since 2009. The on-detector electronics (front-end) part of the current readout electronics of the calorimeters measures the ionization current signals by means of preamplifiers, shapers and digitizers and then transfers the data to the off-detector electronics (back-end) for further elaboration, via optical links. Only the data selected by the level-1 calorimeter trigger system are transferred, achieving a bandwidth reduction to 1.6 Gbps. The analog trigger sum sig...

  3. Microfluidic Flame Barrier

    Science.gov (United States)

    Mungas, Gregory S. (Inventor); Fisher, David J. (Inventor); Mungas, Christopher (Inventor)

    2013-01-01

    Propellants flow through specialized mechanical hardware that is designed for effective and safe ignition and sustained combustion of the propellants. By integrating a micro-fluidic porous media element between a propellant feed source and the combustion chamber, an effective and reliable propellant injector head may be implemented that is capable of withstanding transient combustion and detonation waves that commonly occur during an ignition event. The micro-fluidic porous media element is of specified porosity or porosity gradient selected to be appropriate for a given propellant. Additionally the propellant injector head design integrates a spark ignition mechanism that withstands extremely hot running conditions without noticeable spark mechanism degradation.

  4. Fast calorimeter simulation in LHCb

    CERN Multimedia

    CERN. Geneva

    2018-01-01

    Fast calorimeter simulation in LHCb In HEP experiments CPU resources required by MC simulations are constantly growing and become a very large fraction of the total computing power (greater than 75%). At the same time the pace of performance improvements from technology is slowing down, so the only solution is a more efficient use of resources. Efforts are ongoing in the LHC experiments to provide multiple options for simulating events in a faster way when higher statistics is needed. A key of the success for this strategy is the possibility of enabling fast simulation options in a common framework with minimal action by the final user. In this talk we will describe the solution adopted in Gauss, the LHCb simulation software framework, to selectively exclude particles from being simulated by the Geant4 toolkit and to insert the corresponding hits generated in a faster way. The approach, integrated within the Geant4 toolkit, has been applied to the LHCb calorimeter but it could also be used for other subdetec...

  5. Fast infectious diseases diagnostics based on microfluidic biochip system

    Directory of Open Access Journals (Sweden)

    Qin Huang

    2017-03-01

    Full Text Available Molecular diagnostics is one of the most important tools currently in use for clinical pathogen detection due to its high sensitivity, specificity, and low consume of sample and reagent is keyword to low cost molecular diagnostics. In this paper, a sensitive DNA isothermal amplification method for fast clinical infectious diseases diagnostics at aM concentrations of DNA was developed using a polycarbonate (PC microfluidic chip. A portable confocal optical fluorescence detector was specifically developed for the microfluidic chip that was capable of highly sensitive real-time detection of amplified products for sequence-specific molecular identification near the optical diffraction limit with low background. The molecular diagnostics of Listeria monocytogenes with nucleic acid extracted from stool samples was performed at a minimum DNA template concentration of 3.65aM, and a detection limit of less than five copies of genomic DNA. Contrast to the general polymerase chain reaction (PCR at eppendorf (EP tube, the detection time in our developed method was reduced from 1.5h to 45min for multi-target parallel detection, the consume of sample and reagent was dropped from 25μL to 1.45μL. This novel microfluidic chip system and method can be used to develop a micro total analysis system as a clinically relevant pathogen molecular diagnostics method via the amplification of targets, with potential applications in biotechnology, medicine, and clinical molecular diagnostics.

  6. Aluminum nano-cantilevers for high sensitivity mass sensors

    DEFF Research Database (Denmark)

    Davis, Zachary James; Boisen, Anja

    2005-01-01

    We have fabricated Al nano-cantilevers using a very simple one mask contact UV lithography technique with lateral dimensions under 500 nm and vertical dimensions of approximately 100 nm. These devices are demonstrated as highly sensitive mass sensors by measuring their dynamic properties. Further...

  7. A high-resolution mK-calorimeter applying SQUID-thermometry

    Energy Technology Data Exchange (ETDEWEB)

    Reifenberger, Andreas; Leps, Norman; Fleischmann, Andreas; Pies, Christian; Enss, Christian; Klingeler, Ruediger [Kirchhoff-Institut fuer Physik, Universitaet Heidelberg, INF 227,69120 Heidelberg (Germany)

    2012-07-01

    A new calorimeter for measuring single-crystalline samples of mg-size at ultra-low temperatures is described. Thermometry is done by means of a paramagnetic sensor material (Er-doped Au) in a low magnetic field. A temperature change results in a magnetization change which can be read out as change in magnetic flux by a superconducting quantum interference device (SQUID). This enables measurements in a wide temperature range (theoretically from 1 mK-1 K) with very high sensitivities. The bolometric design exhibits low addenda heat capacity and allows measurements of heat capacities from nJ/K to {mu}J/K by means of a temperature-relaxation method. The performance of the device is compared to a commercially available Quantum Design calorimeter in elsewise unchanged experimental settings in the temperature range from 15 mK to 500 mK.

  8. Intercalibration of the ZEUS high resolution and backing calorimeters

    International Nuclear Information System (INIS)

    Abramowicz, H.; Czyrkowski, H.; Derlicki, A.; Krzyzanowski, M.; Kudla, I.; Kusmierz, W.; Nowak, R.J.; Pawlak, J.M.; Rajca, A.; Stopczynski, A.; Walczak, R.; Zarnecki, A.F.; Kowalski, T.Z.

    1991-07-01

    We have studied the combined performance of two calorimeters, the high resolution uranium-scintillator prototype of the ZEUS forward calorimeter (FCAL), followed by a prototype of the coarser ZEUS backing calorimeter (BAC), made out of thick iron plates interleaved with planes of aluminium proportional chambers. The test results, obtained in an exposure of the calorimeter system to a hadron test beam at the CERN-SPS, show that the backing calorimeter does fulfil its role of recognizing the energy leaking out of the FCAL calorimeter. The measurement of this energy is feasible, if an appropriate calibration of the BAC calorimeter is performed. (orig.)

  9. Intercalibration of the ZEUS high resolution and backing calorimeters

    International Nuclear Information System (INIS)

    Abramowicz, H.; Czyrkowski, H.; Derlicki, A.; Krzyzanowski, M.; Kudla, I.; Kusmierz, W.; Nowak, R.J.; Pawlak, J.M.; Rajca, A.; Stopczynski, A.; Walczak, R.; Zarnecki, A.F.; Kowalski, T.Z.

    1992-01-01

    We have studied the combined performance of two calorimeters, the high resolution uranium-scintillator prototype of the ZEUS forward calorimeter (FCAL), followed by a prototype of the coarser ZEUS backing calorimeter (BAC), made out of thick iron plates interleaved with planes of aluminium proportional chambers. The test results, obtained in an exposure of the calorimeter system to a hadron test beam at the CERN SPS, show that the backing calorimeter does fulfil its role of recognizing the energy leaking out of the FCAL calorimeter. The measurement of this energy is feasible, if an appropriate calibration of the BAC calorimeter is performed. (orig.)

  10. Large capacity water and air bath calorimeters

    International Nuclear Information System (INIS)

    James, S.J.; Kasperski, P.W.; Renz, D.P.; Wetzel, J.R.

    1993-01-01

    EG and G Mound Applied Technologies has developed an 11 in. x 17 in. sample size water bath and an 11 in. x 17 in. sample size air bath calorimeter which both function under servo control mode of operation. The water bath calorimeter has four air bath preconditioners to increase sample throughput and the air bath calorimeter has two air bath preconditioners. The large capacity calorimeters and preconditioners were unique to Mound design which brought about unique design challenges. Both large capacity systems calculate the optimum set temperature for each preconditioner which is available to the operator. Each system is controlled by a personal computer under DOS which allows the operator to download data to commercial software packages when the calorimeter is idle. Qualification testing yielded a one standard deviation of 0.6% for 0.2W to 3.0W Pu-238 heat standard range in the water bath calorimeter and a one standard deviation of 0.3% for the 6.0W to 20.0W Pu-238 heat standard range in the air bath calorimeter

  11. Numerical Optimization in Microfluidics

    DEFF Research Database (Denmark)

    Jensen, Kristian Ejlebjærg

    2017-01-01

    Numerical modelling can illuminate the working mechanism and limitations of microfluidic devices. Such insights are useful in their own right, but one can take advantage of numerical modelling in a systematic way using numerical optimization. In this chapter we will discuss when and how numerical...... optimization is best used....

  12. Enzyme detection by microfluidics

    DEFF Research Database (Denmark)

    2013-01-01

    Microfluidic-implemented methods of detecting an enzyme, in particular a DNA-modifying enzyme, are provided, as well as methods for detecting a cell, or a microorganism expressing said enzyme. The enzyme is detected by providing a nucleic acid substrate, which is specifically targeted...... by that enzyme...

  13. Microfluidics for medical applications

    NARCIS (Netherlands)

    van den Berg, Albert; van den Berg, A.; Segerink, L.I.; Segerink, Loes Irene; Unknown, [Unknown

    2015-01-01

    Lab-on-a-chip devices for point of care diagnostics have been present in clinics for several years now. Alongside their continual development, research is underway to bring the organs and tissue on-a-chip to the patient, amongst other medical applications of microfluidics. This book provides the

  14. Chemistry in Microfluidic Channels

    Science.gov (United States)

    Chia, Matthew C.; Sweeney, Christina M.; Odom, Teri W.

    2011-01-01

    General chemistry introduces principles such as acid-base chemistry, mixing, and precipitation that are usually demonstrated in bulk solutions. In this laboratory experiment, we describe how chemical reactions can be performed in a microfluidic channel to show advanced concepts such as laminar fluid flow and controlled precipitation. Three sets of…

  15. Microfluidic isotachophoresis: A review

    Czech Academy of Sciences Publication Activity Database

    Smejkal, P.; Bottenus, D.; Breadmore, M. C.; Guijt, R. M.; Ivory, C. F.; Foret, František; Macka, M.

    2013-01-01

    Roč. 34, č. 11 (2013), s. 1493-1509 ISSN 0173-0835 R&D Projects: GA ČR(CZ) GAP301/11/2055 Institutional support: RVO:68081715 Keywords : chip * isotachophoresis * microfluidics * miniaturization Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 3.161, year: 2013

  16. Non-compensation of the ATLAS barrel combined calorimeter prototype

    International Nuclear Information System (INIS)

    Kul'chitskij, Yu.A.; Kuz'min, M.V.

    1998-01-01

    The e / π ratio for the ATLAS Barrel Combined Calorimeter Prototype, composed from electromagnetic LArg calorimeter and hadronic Tile calorimeter was investigated. Response of Combined Calorimeter on pions and electrons in the energy region of 20-300 GeV was studied. Found e / h = 1.37 ± 0.01 ± 0.02 is in good agreement with the results from previous Combined Calorimeter tests but has more precisions

  17. First results from the SLD silicon calorimeters

    International Nuclear Information System (INIS)

    Berridge, S.C.; Bugg, W.M.; Kroeger, R.S.; Weidemann, A.W.; White, S.L.

    1992-07-01

    The small-angle calorimeters of the SLD were successfully operated during the recent SLC engineering run. The Luminosity Monitor and Small-Angle Tagger (LMSAT) covers the angular region between 28 and 68 milliradians from the beam axis, while the Medium-Angle Silicon Calorimeter (MASC) covers the 68--190 milliradian region. Both are silicon-tungsten sampling calorimeters; the LMSAT employs 23 layers of 0.86 X 0 sampling, while the MASC has 10 layers of 1.74 X 0 sampling. We present results from the first run of the SLC with the SLD on beamline

  18. Data acquisition system for LHCb calorimeter

    International Nuclear Information System (INIS)

    Dai Gang; Gong Guanghua; Shao Beibei

    2007-01-01

    LHCb Calorimeter system is mainly used to identify and measure the energy of the photon, electron, hadron produced by the collision of proton. TELL1 is a common data acquisition platform based on FPGA for LHCb experiment. It is used to adopt custom data acquisition and process method for every detector and provide the data standard for the CPU matrix. This paper provides a novel DAQ and data process model in VHDL for Calorimeter. According to this model. We have built an effective Calorimeter DAQ system, which would be used in LHCb Experiment. (authors)

  19. Calorimeter prediction based on multiple exponentials

    International Nuclear Information System (INIS)

    Smith, M.K.; Bracken, D.S.

    2002-01-01

    Calorimetry allows very precise measurements of nuclear material to be carried out, but it also requires relatively long measurement times to do so. The ability to accurately predict the equilibrium response of a calorimeter would significantly reduce the amount of time required for calorimetric assays. An algorithm has been developed that is effective at predicting the equilibrium response. This multi-exponential prediction algorithm is based on an iterative technique using commercial fitting routines that fit a constant plus a variable number of exponential terms to calorimeter data. Details of the implementation and the results of trials on a large number of calorimeter data sets will be presented

  20. ALICE Zero Degree Calorimeter (ZDC), General Pictures.

    CERN Multimedia

    2003-01-01

    The ZDC Calorimeter for spectator neutrons is made by 44 slabs of W-alloy; each slab has 44 grooves where quartz fibres are placed. The charged particles of the hadronic shower generated by the neutrons make Cerenkov light in the fibres and the light is collected by photomultipliers. Photos from 1 to 9 show the front-face of the calorimeter. Photo n. 10 shows the rear of the calorimeter where the fibres are divided in several groups to go to the different PMs.

  1. Calibration and performance of the CHORUS calorimeter

    International Nuclear Information System (INIS)

    Buontempo, S.; Capone, A.; Cocco, A.G.; De Pedis, D.; Di Capua, E.; Dore, U.; Ereditato, A.; Ferroni, M.; Fiorillo, G.; Loverre, P.F.; Luppi, C.; Macina, D.; Marchetti-Stasi, F.; Mazzoni, M.A.; Migliozzi, P.; Palladino, V.; Piredda, G.; Ricciardi, S.; Righini, P.P.; Saitta, B.; Santacesaria, R.; Strolin, P.; Zucchelli, P.

    1995-01-01

    A high resolution calorimeter has been built for CHORUS, an experiment which searches for ν μ →ν τ oscillation in the CERN neutrino beam. Aim of the calorimeter is to measure the energy and direction of hadronic showers produced in interactions of the neutrinos in a nuclear emulsion target and to track through-going muons. It is a longitudinally segmented sampling device made of lead and scintillating fibers or strips. This detector has been exposed to beams of pions and electrons of defined momentum for calibration. The method used for energy calibration and results on the calorimeter performance are reported. (orig.)

  2. CMS Calorimeter Trigger Phase I upgrade

    International Nuclear Information System (INIS)

    Klabbers, P; Gorski, T; Bachtis, M; Dasu, S; Fobes, R; Grothe, M; Ross, I; Smith, W H; Compton, K; Farmahini-Farahani, A; Gregerson, A; Seemuth, D; Schulte, M

    2012-01-01

    We present a design for the Phase-1 upgrade of the Compact Muon Solenoid (CMS) calorimeter trigger system composed of FPGAs and Multi-GBit/sec links that adhere to the μTCA crate Telecom standard. The upgrade calorimeter trigger will implement algorithms that create collections of isolated and non-isolated electromagnetic objects, isolated and non-isolated tau objects and jet objects. The algorithms are organized in several steps with progressive data reduction. These include a particle cluster finder that reconstructs overlapping clusters of 2x2 calorimeter towers and applies electron identification, a cluster overlap filter, particle isolation determination, jet reconstruction, particle separation and sorting.

  3. MARK II end cap calorimeter electronics

    International Nuclear Information System (INIS)

    Jared, R.C.; Haggerty, J.S.; Herrup, D.A.; Kirsten, F.A.; Lee, K.L.; Olson, S.R.; Wood, D.R.

    1985-10-01

    An end cap calorimeter system has been added to the MARK II detector in preparation for its use at the SLAC Linear Collider. The calorimeter uses 8744 rectangular proportional counter tubes. This paper describes the design features of the data acquisition electronics that has been installed on the calorimeter. The design and use of computer-based test stands for the amplification and signal-shaping components is also covered. A portion of the complete system has been tested in a beam at SLAC. In these initial tests, using only the calibration provided by the test stands, a resolution of 18%/√E was achieved

  4. The D0 calorimeter trigger

    International Nuclear Information System (INIS)

    Guida, J.

    1992-12-01

    The D0 calorimeter trigger system consists of many levels to make physics motivated trigger decisions. The Level-1 trigger uses hardware techniques to reduce the trigger rate from ∼ 100kHz to 200Hz. It forms sums of electromagnetic and hadronic energy, globally and in towers, along with finding the missing transverse energy. A minimum energy is set on these energy sums to pass the event. The Level-2 trigger is a set of software filters, operating in a parallel-processing microvax farm which further reduces the trigger rate to a few Hertz. These filters will reject events which lack electron candidates, jet candidates, or missing transverse energy in the event. The performance of these triggers during the early running of the D0 detector will also be discussed

  5. Tritium calorimeter setup and operation

    CERN Document Server

    Rodgers, D E

    2002-01-01

    The LBNL tritium calorimeter is a stable instrument capable of measuring tritium with a sensitivity of 25 Ci. Measurement times range from 8-hr to 7-days depending on the thermal conductivity and mass of the material being measured. The instrument allows accurate tritium measurements without requiring that the sample be opened and subsampled, thus reducing personnel exposure and radioactive waste generation. The sensitivity limit is primarily due to response shifts caused by temperature fluctuation in the water bath. The fluctuations are most likely a combination of insufficient insulation from ambient air and precision limitations in the temperature controller. The sensitivity could probably be reduced to below 5 Ci if the following improvements were made: (1) Extend the external insulation to cover the entire bath and increase the top insulation. (2) Improve the seal between the air space above the bath and the outside air to reduce evaporation. This will limit the response drift as the water level drops. (...

  6. Liquid Krypton Calorimeter Calibration Software

    CERN Document Server

    Hughes, Christina Lindsay

    2013-01-01

    Calibration of the liquid krypton calorimeter (LKr) of the NA62 experiment is managed by a set of standalone programs, or an online calibration driver. These programs are similar to those used by NA48, but have been updated to utilize classes and translated to C++ while maintaining a common functionality. A set of classes developed to handle communication with hardware was used to develop the three standalone programs as well as the main driver program for online calibration between bursts. The main calibration driver has been designed to respond to run control commands and receive burst data, both transmitted via DIM. In order to facilitate the process of reading in calibration parameters, a serializable class has been introduced, allowing the replacement of standard text files with XML configuration files.

  7. Are starburst galaxies proton calorimeters?

    Science.gov (United States)

    Wang, Xilu; Fields, Brian D.

    2018-03-01

    Several starburst galaxies have been observed in the GeV and TeV bands. In these dense environments, gamma-ray emission should be dominated by cosmic ray (CR) interactions with the interstellar medium (pcrpism → π0 → γγ). Indeed, starbursts may act as proton `calorimeters' where a substantial fraction of CR energy input is emitted in gamma-rays. Here, we build a one-zone, `thick-target' model implementing calorimetry and placing a firm upper bound on gamma-ray emission from CR interactions. The model assumes that CRs are accelerated by supernovae (SNe), and all suffer nuclear interactions rather than escape. Our model has only two free parameters: the CR proton acceleration energy per SN ɛcr, and the proton injection spectral index s. We calculate the pionic gamma-ray emission from 10 MeV to 10 TeV, and derive thick-target parameters for six galaxies with Fermi, H.E.S.S., and/or VERITAS data. Our model provides good fits for the M82 and NGC 253, and yields ɛcr and s values suggesting that SN CR acceleration is similar in starbursts and in our Galaxy. We find that these starbursts are indeed nearly if not fully proton calorimeters. For NGC 4945 and NGC 1068, the models are consistent with calorimetry but are less well-constrained due to the lack of TeV data. However, the Circinus galaxy and the ultra-luminous infrared galaxy Arp 220 exceed our pionic upper-limit; possible explanations are discussed.

  8. A highly segmented and compact liquid argon calorimeter for the LHC the TGT calorimeter

    CERN Document Server

    Berger, C; Geulig, H; Pierschel, G; Siedling, R; Tutas, J; Wlochal, M; Wotschack, J; Cheplakov, A P; Eremeev, R V; Feshchenko, A; Gavrishchuk, O P; Kazarinov, Yu M; Khrenov, Yu V; Kukhtin, V V; Ladygin, E; Obudovskij, V; Shalyugin, A N; Tolmachev, V T; Volodko, A G; Geweniger, C; Hanke, P; Kluge, E E; Krause, J; Putzer, A; Tittel, K; Wunsch, M; Bán, J; Bruncko, Dusan; Kriván, F; Kurca, T; Murín, P; Sándor, L; Spalek, J; Aderholz, Michael; Brettel, H; Dydak, Friedrich; Fent, J; Huber, J; Hajduk, L; Jakobs, K; Kiesling, C; Oberlack, H; Schacht, P; Stiegler, U; Bogolyubsky, M Yu; Chekulaev, S V; Kiryunin, A E; Kurchaninov, L L; Levitsky, M S; Maximov, V V; Minaenko, A A; Moiseev, A M; Semenov, P A; CERN. Geneva. Detector Research and Development Committee

    1992-01-01

    The development of a fast, highly granular and compact electromagnetic liquid argon calorimeter is proposed as an R&D project for an LHC calorimeter with full rapidity coverage. The proposed ``Thin Gap Turbine'' (TGT) calorimeter offers uniform energy response and constant energy resolution independent of the production angle of the impinging particle and of its impact position at the calorimeter. An important aspect of the project is the development of electronics for fast signal processing matched to the short charge collection time in the TGT read-out cell. The system aspects of the integration of a high degree of signal processing into the liquid argon would be investigated.

  9. PREFACE: Nano- and microfluidics Nano- and microfluidics

    Science.gov (United States)

    Jacobs, Karin

    2011-05-01

    The field of nano- and microfluidics emerged at the end of the 1990s parallel to the demand for smaller and smaller containers and channels for chemical, biochemical and medical applications such as blood and DNS analysis [1], gene sequencing or proteomics [2, 3]. Since then, new journals and conferences have been launched and meanwhile, about two decades later, a variety of microfluidic applications are on the market. Briefly, 'the small flow becomes mainstream' [4]. Nevertheless, research in nano- and microfluidics is more than downsizing the spatial dimensions. For liquids on the nanoscale, surface and interface phenomena grow in importance and may even dominate the behavior in some systems. The studies collected in this special issue all concentrate on these type of systems and were part ot the priority programme SPP1164 'Nano- and Microfluidics' of the German Science Foundation (Deutsche Forschungsgemeinschaft, DFG). The priority programme was initiated in 2002 by Hendrik Kuhlmann and myself and was launched in 2004. Friction between a moving liquid and a solid wall may, for instance, play an important role so that the usual assumption of a no-slip boundary condition is no longer valid. Likewise, the dynamic deformations of soft objects like polymers, vesicles or capsules in flow arise from the subtle interplay between the (visco-)elasticity of the object and the viscous stresses in the surrounding fluid and, potentially, the presence of structures confining the flow like channels. Consequently, new theories were developed ( see articles in this issue by Münch and Wagner, Falk and Mecke, Bonthuis et al, Finken et al, Almenar and Rauscher, Straube) and experiments were set up to unambiguously demonstrate deviations from bulk, or 'macro', behavior (see articles in this issue by Wolff et al, Vinogradova and Belyaev, Hahn et al, Seemann et al, Grüner and Huber, Müller-Buschbaum et al, Gutsche et al, Braunmüller et al, Laube et al, Brücker, Nottebrock et al

  10. Performance of terahertz metamaterials as high-sensitivity sensor

    Science.gov (United States)

    He, Yanan; Zhang, Bo; Shen, Jingling

    2017-09-01

    A high-sensitivity sensor based on the resonant transmission characteristics of terahertz (THz) metamaterials was investigated, with the proposal and fabrication of rectangular bar arrays of THz metamaterials exhibiting a period of 180 μm on a 25 μm thick flexible polyimide. Varying the size of the metamaterial structure revealed that the length of the rectangular unit modulated the resonant frequency, which was verified by both experiment and simulation. The sensing characteristics upon varying the surrounding media in the sample were tested by simulation and experiment. Changing the surrounding medium from that of air to that of alcohol or oil produced resonant frequency redshifts of 80 GHz or 150 GHz, respectively, which indicates that the sensor possessed a high sensitivity of 667 GHz per unit of refractive index. Finally, the influence of the sample substrate thickness on the sensor sensitivity was investigated by simulation. It may be a reference for future sensor design.

  11. What's new with the CMS hadron calorimeter

    CERN Document Server

    Hagopian, V

    2002-01-01

    The CMS Hadron Calorimeter is designed to measure hadron jets, single hadrons and single mu 's. The central barrel and the two end caps, made of brass and scintillators cover the ¿ eta ¿ range of 0.0 to 3.0. The two forward calorimeters made of iron and quartz fibers extend the ¿ eta ¿ range to 5.0. Scintillators are also placed outside of the magnet coil, within the muon system to measure the energy leakage from the central barrel. The construction of the calorimeter is about 50% complete. Several design changes were made to simplify the calorimeter and reduce the cost. The longitudinal segmentation of the central barrel and end caps was reduced by one unit. The quartz fiber diameter was doubled from 300 to 600 microns. Improvements were made to the hybrid photodetectors (HPD) and various other components. The special purpose ADC (QIE) and other electronics are in prototype stage. (3 refs).

  12. Upgrading the Atlas Tile Calorimeter Electronics

    CERN Document Server

    Popeneciu, G; The ATLAS collaboration

    2014-01-01

    Tile Calorimeter is the central hadronic calorimeter of the ATLAS experiment at LHC. Around 2024, after the upgrade of the LHC the peak luminosity will increase by a factor of 5 compared to the design value, thus requiring an upgrade of the Tile Calorimeter readout electronics. Except the photomultipliers tubes (PMTs), most of the on- and off-detector electronics will be replaced, with the aim of digitizing all PMT pulses at the front-end level and sending them with 10 Gb/s optical links to the back-end electronics. One demonstrator prototype module is planned to be inserted in Tile Calorimeter in 2015 that will include hybrid electronic components able to probe the new design.

  13. Modeling response variation for radiometric calorimeters

    International Nuclear Information System (INIS)

    Mayer, R.L. II.

    1986-01-01

    Radiometric calorimeters are widely used in the DOE complex for accountability measurements of plutonium and tritium. Proper characterization of response variation for these instruments is, therefore, vital for accurate assessment of measurement control as well as for propagation of error calculations. This is not difficult for instruments used to measure items within a narrow range of power values; however, when a single instrument is used to measure items over a wide range of power values, improper estimates of uncertainty can result since traditional error models for radiometric calorimeters assume that uncertainty is not a function of sample power. This paper describes methods which can be used to accurately estimate random response variation for calorimeters used to measure items over a wide range of sample powers. The model is applicable to the two most common modes of calorimeter operation: heater replacement and servo control. 5 refs., 4 figs., 1 tab

  14. The Compact Muon Solenoid (CMS) hadron calorimeter

    International Nuclear Information System (INIS)

    Hagopian, Vasken

    1999-01-01

    The Hadron Calorimeter of the CMS detector for the CERN LHC accelerator is designed to measure hadron jets as well as single hadrons. It has six segments. The central barrel made of brass and scintillators covers the vertical bar η vertical bar range of about 0 to 1.3. Two End Caps, also made of brass and scintillators extends the vertical bar η vertical bar range to 3.0. Two Forward calorimeters made of iron and quartz fibers cover the range 3.0 to 5.0. Since the barrel portion of the calorimeter is only 6.5 interaction lengths, the outer barrel will sample, by scintillators, outside the magnet coil and cryostat. Progress has been made on all subsystems and prototypes have been built. We now have a better understanding of magnetic field effects on calorimeters

  15. CDF End Plug calorimeter Upgrade Project

    International Nuclear Information System (INIS)

    Apollinari, G.; de Barbaro, P.; Mishina, M.

    1994-01-01

    We report on the status of the CDF End Plug Upgrade Project. In this project, the CDF calorimeters in the end plug and the forward regions will be replaced by a single scintillator based calorimeter. After an extensive R ampersand D effort on the tile/fiber calorimetry, we have now advanced to a construction phase. We review the results of the R ampersand D leading to the final design of the calorimeters and the development of tooling devised for this project. The quality control program of the production of the electromagnetic and hadronic calorimeters is described. A shower maximum detector for the measurement of the shower centroid and the shower profile of electrons, γ and π 0 has been designed. Its performance requirements, R ampersand D results and mechanical design are discussed

  16. Performance of the ATLAS hadronic Tile calorimeter

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00304670; The ATLAS collaboration

    2016-01-01

    The Tile Calorimeter (TileCal) of the ATLAS experiment at the LHC is the central hadronic calorimeter designed for energy reconstruction of hadrons, jets, tau-particles and missing transverse energy. TileCal is a scintillator-steel sampling calorimeter and it covers the region of pseudorapidity < 1.7. The scintillation light produced in the scintillator tiles is transmitted to photomultiplier tubes (PMTs). Signals from the PMTs are amplified, shaped and digitized by sampling the signal every 25 ns. Each stage of the signal production from scintillation light to the signal reconstruction is monitored and calibrated. Results on the calorimeter operation and performance are presented, including the calibration, stability, absolute energy scale, uniformity and time resolution. These results show that the TileCal performance is within the design requirements and has given essential contribution to reconstructed objects and physics results.

  17. Performance of the ATLAS Zero Degree Calorimeter

    CERN Document Server

    Leite, M; The ATLAS collaboration

    2013-01-01

    The ATLAS Zero Degree Calorimeter (ZDC) at the Large Hadron Collider (LHC) is a set of two sampling calorimeters modules symmetrically located at 140m from the ATLAS interaction point. The ZDC covers a pseudorapidity range of |eta| > 8.3 and it is both longitudinally and transversely segmented, thus providing energy and position information of the incident particles. The ZDC is installed between the two LHC beam pipes, in a configuration such that only the neutral particles produced at the interaction region can reach this calorimeter. The ZDC uses Tungsten plates as absorber material and rods made of quartz interspersed in the absorber as active media. The energetic charged particles crossing the quartz rods produces Cherenkov light which is then detected by photomultipliers and sent to the front end electronics for processing, in a total of 120 individual electronic channels. The Tungsten plates and quartz rods are arranged in a way to segment the calorimeters in 4 longitudinal sections. The first section (...

  18. Online high sensitivity measurement system for transuranic aerosols

    International Nuclear Information System (INIS)

    Kordas, J.F.; Phelps, P.L.

    1976-01-01

    A measurement system for transuranic aerosols has been designed that will be able to withstand the corrosive nature of stack effluents and yet have extremely high sensitivity. It will be capable of measuring 1 maximum permissible concentration (MPC) of plutonium or americium in 30 minutes with a fractional standard deviation of less than 0.33. Background resulting from 218 Po is eliminated by alpha energy discrimination and a decay scheme analysis. A microprocessor controls all data acquisition, data reduction, and instrument calibration

  19. Fractal Dimension of Particle Showers Measured in a Highly Granular Calorimeter

    CERN Document Server

    Ruan, Manqi; Bourdy, Vincent; Brients, Jean-Claude; Videau, Henri

    2014-01-01

    fractal dimension of showers measured in a high granularity calorimeter designed for a future lepton collider. The shower fractal dimension reveals detailed information of the spatial configuration of the shower. It is found to be characteristic of the type of interaction and highly sensitive to the nature of the incident particle. Using the shower fractal dimension, we demonstrate a particle identification algorithm that can efficiently separate electromagnetic showers, hadronic showers and non-showering tracks. We also find a logarithmic dependence of the shower fractal dimension on the particle energy.

  20. Sampling calorimeters in high energy physics

    International Nuclear Information System (INIS)

    Gordon, H.A.; Smith, S.D.

    1980-01-01

    Attention is given to sampling calorimeters - those instruments in which part of the shower is sampled in an active medium sandwiched between absorbing layers. A very cursory overview is presented of some fundamental aspects of sampling calorimeters. First the properties of shower development are described for both the electromagnetic and hadronic cases. Then examples of various readout schemes are discussed. Finally, some currently promising new ideas in calorimetry are described

  1. Heavy ion studies with CMS HF calorimeter

    International Nuclear Information System (INIS)

    Damgov, I.; Genchev, V.; Kolosov, V.A.; Lokhtin, I.P.; Petrushanko, S.V.; Sarycheva, L.I.; Teplov, S.Yu.; Shmatov, S.V.; Zarubin, P.I.

    2001-01-01

    The capability of the very forward (HF) calorimeter of the CMS detector at LHC to be applied to specific studies with heavy ion beams is discussed. The simulated responses of the HF calorimeter to nucleus-nucleus collisions are used for the analysis of different problems: reconstruction of the total energy flow in the forward rapidity region, accuracy of determination of the impact parameter of collision, study of fluctuations of the hadronic-to-electromagnetic energy ratio, fast inelastic event selection

  2. The new RD52 (DREAM) fiber calorimeter

    International Nuclear Information System (INIS)

    Wigmans, Richard

    2012-01-01

    Simultaneous detection of the Cerenkov light and scintillation light produced in hadron showers makes it possible to measure the electromagnetic shower fraction event by event and thus eliminate the detrimental effects of fluctuations in this fraction on the performance of calorimeters. In the RD52 (DREAM) project, the possibilities of this dual-readout calorimetry are investigated and optimized. In this talk, the first test results of prototype modules for the new full-scale fiber calorimeter are presented.

  3. The performance of the ZEUS calorimeter

    International Nuclear Information System (INIS)

    Crittenden, J.A.

    1994-12-01

    The ZEUS experiment has now completed its third year of operation at the electron-proton collider HERA. The uranium/scintillator sampling calorimeter surrounding the inner tracking detectors has proven an essential component for the online triggering algorithms, for offline event-type identification, for kinematic variable reconstruction, and for a ariety of physics analyses. This paper summarizes the experimental context, the operating characteristics, the calibration techniques, and the performance of the calorimeter during its first three years of operation. (orig.)

  4. The electromagnetic calorimeter of the NOMAD experiment

    Energy Technology Data Exchange (ETDEWEB)

    Autiero, D; Baldo-Ceolin, M; Barichello, G; Bianchi-Bonaiti, V; Bobisut, F; Cardini, A; Cattaneo, P W; Cavasinni, V; Conta, C; Del Prete, T; De Santo, A; Di Lella, L; Ferrari, R; Flaminio, V; Fraternali, M; Gibin, D; Gninenko, S N; Guglielmi, A; Iacopini, E; Kovzelev, A V; La Rotonda, L; Lanza, A; Laveder, M; Lazzeroni, C; Livan, M; Mezzetto, M; Orestano, D; Pastore, F; Pennacchio, E; Petti, R; Polesello, G; Renzoni, G; Rimoldi, A; Roda, C; Sconza, A; Sobczynski, C; Valdata-Nappi, M; Vascon, M; Vercesi, V; Visentin, L; Volkov, S A [Pisa Univ. (Italy). Dipt. di Fisica; [Istituto Nazionale di Fisica Nucleare, Pisa (Italy); [Dipartimento di Fisica, Universita di Padova and INFN, Sezione di Padova, Padova (Italy); [Dipartimento di Fisica Nucleare e Teorica, Universita di Pavia and INFN, Sezione di Pavia, Pavia (Italy); [CERN, Geneva (Switzerland); [Dipartimento di Fisica, Universita di Firenze and INFN, Sezione di Firenze, Firenze (Italy); [Institute of Nuclear Research, INR, Moscow (Russian Federation); [Dipartimento di Fisica, Universita della Calabria and INFN, Gruppo Collegato di Cosenza, Cosenza (Italy)

    1996-05-01

    A description is given of the NOMAD electromagnetic calorimeter, consisting of 875 lead-glass counters read out by two-stage photomultipliers and a low noise electronic chain. The detector operates in a 0.4 T magnetic field transverse to the counter axis. The paper discusses the design criteria, the lead-glass characteristics, the properties of the read out chain and provides a summary of the calorimeter performance. (orig.).

  5. Radiation-Hard Quartz Cerenkov Calorimeters

    International Nuclear Information System (INIS)

    Akgun, U.; Onel, Y.

    2006-01-01

    New generation hadron colliders are going to reach unprecedented energies and radiation levels. Quartz has been identified as a radiation-hard material that can be used for Cerenkov calorimeters of the future experiments. We report from the radiation hardness tests performed on quartz fibers, as well as the characteristics of the quartz fiber and plate Cerenkov calorimeters that have been built, designed, and proposed for the CMS experiment

  6. The high resolution spaghetti hadron calorimeter

    International Nuclear Information System (INIS)

    Jenni, P.; Sonderegger, P.; Paar, H.P.; Wigmans, R.

    1987-01-01

    It is proposed to build a prototype for a hadron calorimeter with scintillating plastic fibres as active material. The absorber material is lead. Provided that these components are used in the appropriate volume ratio, excellent performance may be expected, e.g. an energy resolution of 30%/√E for jet detection. The proposed design offers additional advantages compared to the classical sandwich calorimeter structures in terms of granularity, hermiticity, uniformity, compactness, readout, radiation resistivity, stability and calibration. 22 refs.; 7 figs

  7. A neutron calorimeter as a fusion diagnostic

    International Nuclear Information System (INIS)

    Proctor, A.E.; Harker, Y.D.; Neischmidt, E.B.

    1986-01-01

    A calorimeter is described which is applicable as a fusion neutron diagnostic. The advantages of the device are discussed, including: low sensitivity to thermal neutrons, no heat loss to surroundings, large dynamic range, small mass resulting in fair time resolution, and small physical size. The heat generation is provided by neutron induced fissions in a foil of 238 U and a calorimeter is isothermal. The effects, advantages and disadvantages of other target materials are discussed. Also discussed are time resolution and calibration

  8. The NA48 liquid krypton calorimeter

    CERN Document Server

    Gorini, B

    1997-01-01

    The NA48 collaboration goal is to measure the CP violation parameter Re(ɛl/ɛ) at the level of 2 × 10−4. The neutral Kaon decays will be reconstructed by an electromagnetic liquid Krypton calorimeter with fine granularity and a volume almost totally sensible, to obtain excellent position and energy resolution, as well as time resolution. A description of the detector, results from tests of a prototype and the status of the final calorimeter are reported.

  9. The electromagnetic calorimeter of the NOMAD experiment

    International Nuclear Information System (INIS)

    Autiero, D.; Baldo-Ceolin, M.; Barichello, G.; Bianchi-Bonaiti, V.; Bobisut, F.; Cardini, A.; Cattaneo, P.W.; Cavasinni, V.; Conta, C.; Del Prete, T.; De Santo, A.; Di Lella, L.; Ferrari, R.; Flaminio, V.; Fraternali, M.; Gibin, D.; Gninenko, S.N.; Guglielmi, A.; Iacopini, E.; Kovzelev, A.V.; La Rotonda, L.; Lanza, A.; Laveder, M.; Lazzeroni, C.; Livan, M.; Mezzetto, M.; Orestano, D.; Pastore, F.; Pennacchio, E.; Petti, R.; Polesello, G.; Renzoni, G.; Rimoldi, A.; Roda, C.; Sconza, A.; Sobczynski, C.; Valdata-Nappi, M.; Vascon, M.; Vercesi, V.; Visentin, L.; Volkov, S.A.

    1996-01-01

    A description is given of the NOMAD electromagnetic calorimeter, consisting of 875 lead-glass counters read out by two-stage photomultipliers and a low noise electronic chain. The detector operates in a 0.4 T magnetic field transverse to the counter axis. The paper discusses the design criteria, the lead-glass characteristics, the properties of the read out chain and provides a summary of the calorimeter performance. (orig.)

  10. Microfluidic device, and related methods

    Science.gov (United States)

    Wong, Eric W. (Inventor)

    2010-01-01

    A method of making a microfluidic device is provided. The method features patterning a permeable wall on a substrate, and surrounding the permeable wall with a solid, non-permeable boundary structure to establish a microfluidic channel having a cross-sectional dimension less than 5,000 microns and a cross-sectional area at least partially filled with the permeable wall so that fluid flowing through the microfluidic channel at least partially passes through the permeable wall.

  11. ATLAS Tile Calorimeter calibration and monitoring systems

    Science.gov (United States)

    Cortés-González, Arely

    2018-01-01

    The ATLAS Tile Calorimeter is the central section of the hadronic calorimeter of the ATLAS experiment and provides important information for reconstruction of hadrons, jets, hadronic decays of tau leptons and missing transverse energy. This sampling calorimeter uses steel plates as absorber and scintillating tiles as active medium. The light produced by the passage of charged particles is transmitted by wavelength shifting fibres to photomultiplier tubes, located in the outer part of the calorimeter. Neutral particles may also produce a signal after interacting with the material and producing charged particles. The readout is segmented into about 5000 cells, each of them being read out by two photomultipliers in parallel. To calibrate and monitor the stability and performance of each part of the readout chain during the data taking, a set of calibration systems is used. This comprises Cesium radioactive sources, Laser, charge injection elements and an integrator based readout system. Information from all systems allows to monitor and equalise the calorimeter response at each stage of the signal production, from scintillation light to digitisation. Calibration runs are monitored from a data quality perspective and used as a cross-check for physics runs. The data quality efficiency achieved during 2016 was 98.9%. These calibration and stability of the calorimeter reported here show that the TileCal performance is within the design requirements and has given essential contribution to reconstructed objects and physics results.

  12. Performance of the ATLAS hadronic Tile calorimeter

    CERN Document Server

    Van Daalen, Tal Roelof; The ATLAS collaboration

    2018-01-01

    Performance of the ATLAS hadronic Tile calorimeter The Tile Calorimeter (TileCal) of the ATLAS experiment at the LHC is the central hadronic calorimeter designed for the reconstruction of hadrons, jets, tau-particles and missing transverse energy. TileCal is a scintillator-steel sampling calorimeter and it covers the region of pseudorapidity < 1.7. The scintillation light produced in the scintillator tiles is transmitted by wavelength shifting fibers to photomultiplier tubes (PMTs). The analog signals from the PMTs are amplified, shaped and digitized every 25 ns by sampling the signal. About 10000 channels of the front-end electronics measure the signals of the calorimeter with energies ranging from ~30 MeV to ~2 TeV. Each step of the signal reconstruction from scintillation light to the digital pulse reconstruction is monitored and calibrated. The performance of the calorimeter has been studied in-situ employing cosmic ray muons and a large sample of proton-proton collisions acquired during the operations...

  13. ATLAS: last few metresfor the Calorimeter

    CERN Multimedia

    2005-01-01

    On Friday 4th November, the ATLAS Barrel Calorimeter was moved from its assembly point at the side of the ATLAS cavern to the centre of the toroidal magnet system. The detector was finally aligned, to the precision of within a millimetre, on Wednesday 9th November. The ATLAS installation team, led by Tommi Nyman, after having positioned the Barrel Calorimeter in its final location in the ATLAS experimental cavern UX15. The Barrel Calorimeter which will absorb and measure the energy of photons, electrons and hadrons at the core of the ATLAS detector is 8.6 meters in diameter, 6.8 meters long, and weighs over 1600 Tonnes. It consists of two concentric cylindrical detector elements. The innermost comprises aluminium pressure vessels containing the liquid argon electromagnetic calorimeter and the solenoid magnet. The outermost is an assembly of 64 hadron tile calorimeter sectors. Assembled 18 meters away from its final position, the Barrel Calorimeter was relocated with the help of a railway, which allows the ...

  14. Last Few Metres for the Barrel Calorimeter

    CERN Multimedia

    Nyman, T.

    On Friday 4th November, the ATLAS Barrel Calorimeter was moved from its assembly point at the side of the ATLAS cavern to the centre of the toroidal magnet system. The detector was finally aligned, to the precision of within a millimetre, on Wednesday 9th November. The ATLAS installation team, led by Tommi Nyman, after having positioned the Barrel Calorimeter in its final location in the ATLAS experimental cavern UX15. The Barrel Calorimeter which will absorb and measure the energy of photons, electrons and hadrons at the core of the ATLAS detector is 8.6 meters in diameter, 6.8 meters long, and weighs over 1600 Tonnes. It consists of two concentric cylindrical detector elements. The innermost comprises aluminium pressure vessels containing the liquid argon electromagnetic calorimeter and the solenoid magnet. The outermost is an assembly of 64 hadron tile calorimeter sectors. Assembled 18 meters away from its final position, the Barrel Calorimeter was relocated with the help of a railway, which allows ...

  15. Sampling calorimeters in high energy physics

    International Nuclear Information System (INIS)

    Gordon, H.A.; Smith, S.D.

    1981-01-01

    At our current understanding of elementary particle physics, the fundamental constituents are the photon, quarks, gluons and leptons with a few highly forecasted heavy bosons. Calorimeters are essential for detecting all of these particles. Quarks and gluons fragment into many particles - at high energies, so many particles that one may not want to measure each one separately. This group of both charged and neutral particles can only be measured by calorimeters. The energy of an electron needs to be measured by a calorimeter and muon identification is enhanced by the recognition of a minimum ionizing particle passing through the calorimeter. Sampling calorimeters - those instruments in which part of the shower is sampled in an active medium sandwiched between absorbing layers - are reviewed. What follows is a very cursory overview of some fundamental aspects of sampling calorimeters. First, the properties of shower development are described for both the electromagnetic and hadronic cases. Then, examples of various readout schemes are discussed. Finally, some currently promising new ideas in calorimetry are described. 21 references

  16. Performance of the ATLAS Tile Calorimeter

    Science.gov (United States)

    Hrynevich, A.

    2017-06-01

    The Tile Calorimeter (TileCal) is the central scintillator-steel sampling hadronic calorimeter of the ATLAS experiment at the LHC . Jointly with other calorimeters it is designed for energy reconstruction of hadrons, jets, tau-particles and missing transverse energy. The scintillation light produced in the scintillator tiles is transmitted by wavelength shifting fibers to photomultiplier tubes (PMTs). The analog signals from the PMTs are amplified, shaped and digitized by sampling the signal every 25 ns. The TileCal frontend electronics reads out the signals produced by about 10000 channels measuring energies ranging from ~30 MeV to ~2 TeV . Each stage of the signal production from scintillation light to the signal reconstruction is monitored and calibrated. The performance of the calorimeter has been established with cosmic ray muons and the large sample of the proton-proton collisions. The response of high momentum isolated muons is used to study the energy response at the electromagnetic scale, isolated hadrons are used as a probe of the hadronic response and its modelling by the Monte Carlo simulations. The calorimeter time resolution is studied with multijet events. Results on the calorimeter operation and performance are presented, including the calibration, stability, absolute energy scale, uniformity and time resolution. These results show that the TileCal performance is within the design requirements and has given essential contribution to reconstructed objects and physics results.

  17. Methods of making microfluidic devices

    KAUST Repository

    Buttner, Ulrich

    2017-06-01

    Microfluidics has advanced in terms of designs and structures, however, fabrication methods are either time consuming or expensive to produce, in terms of the facilities and equipment needed. A fast and economically viable method is provided to allow, for example, research groups to have access to microfluidic fabrication. Unlike most fabrication methods, a method is provided to fabricate a microfluidic device in one step. In an embodiment, a resolution of 50 micrometers was achieved by using maskless high-resolution digital light projection (MDLP). Bonding and channel fabrication of complex or simple structures can be rapidly incorporated to fabricate the microfluidic devices.

  18. The Microfluidic Jukebox

    Science.gov (United States)

    Tan, Say Hwa; Maes, Florine; Semin, Benoît; Vrignon, Jérémy; Baret, Jean-Christophe

    2014-04-01

    Music is a form of art interweaving people of all walks of life. Through subtle changes in frequencies, a succession of musical notes forms a melody which is capable of mesmerizing the minds of people. With the advances in technology, we are now able to generate music electronically without relying solely on physical instruments. Here, we demonstrate a musical interpretation of droplet-based microfluidics as a form of novel electronic musical instruments. Using the interplay of electric field and hydrodynamics in microfluidic devices, well controlled frequency patterns corresponding to musical tracks are generated in real time. This high-speed modulation of droplet frequency (and therefore of droplet sizes) may also provide solutions that reconciles high-throughput droplet production and the control of individual droplet at production which is needed for many biochemical or material synthesis applications.

  19. Microfluidic redox battery.

    Science.gov (United States)

    Lee, Jin Wook; Goulet, Marc-Antoni; Kjeang, Erik

    2013-07-07

    A miniaturized microfluidic battery is proposed, which is the first membraneless redox battery demonstrated to date. This unique concept capitalizes on dual-pass flow-through porous electrodes combined with stratified, co-laminar flow to generate electrical power on-chip. The fluidic design is symmetric to allow for both charging and discharging operations in forward, reverse, and recirculation modes. The proof-of-concept device fabricated using low-cost materials integrated in a microfluidic chip is shown to produce competitive power levels when operated on a vanadium redox electrolyte. A complete charge/discharge cycle is performed to demonstrate its operation as a rechargeable battery, which is an important step towards providing sustainable power to lab-on-a-chip and microelectronic applications.

  20. Microfluidic Biochip Design

    Science.gov (United States)

    Panzarella, Charles

    2004-01-01

    As humans prepare for the exploration of our solar system, there is a growing need for miniaturized medical and environmental diagnostic devices for use on spacecrafts, especially during long-duration space missions where size and power requirements are critical. In recent years, the biochip (or Lab-on-a- Chip) has emerged as a technology that might be able to satisfy this need. In generic terms, a biochip is a miniaturized microfluidic device analogous to the electronic microchip that ushered in the digital age. It consists of tiny microfluidic channels, pumps and valves that transport small amounts of sample fluids to biosensors that can perform a variety of tests on those fluids in near real time. It has the obvious advantages of being small, lightweight, requiring less sample fluids and reagents and being more sensitive and efficient than larger devices currently in use. Some of the desired space-based applications would be to provide smaller, more robust devices for analyzing blood, saliva and urine and for testing water and food supplies for the presence of harmful contaminants and microorganisms. Our group has undertaken the goal of adapting as well as improving upon current biochip technology for use in long-duration microgravity environments. In addition to developing computational models of the microfluidic channels, valves and pumps that form the basis of every biochip, we are also trying to identify potential problems that could arise in reduced gravity and develop solutions to these problems. One such problem is due to the prevalence of bubbly sample fluids in microgravity. A bubble trapped in a microfluidic channel could be detrimental to the operation of a biochip. Therefore, the process of bubble formation in microgravity needs to be studied, and a model of this process has been developed and used to understand how bubbles develop and move through biochip components. It is clear that some type of bubble filter would be necessary in Space, and

  1. Droplet based microfluidics

    International Nuclear Information System (INIS)

    Seemann, Ralf; Brinkmann, Martin; Pfohl, Thomas; Herminghaus, Stephan

    2012-01-01

    Droplet based microfluidics is a rapidly growing interdisciplinary field of research combining soft matter physics, biochemistry and microsystems engineering. Its applications range from fast analytical systems or the synthesis of advanced materials to protein crystallization and biological assays for living cells. Precise control of droplet volumes and reliable manipulation of individual droplets such as coalescence, mixing of their contents, and sorting in combination with fast analysis tools allow us to perform chemical reactions inside the droplets under defined conditions. In this paper, we will review available drop generation and manipulation techniques. The main focus of this review is not to be comprehensive and explain all techniques in great detail but to identify and shed light on similarities and underlying physical principles. Since geometry and wetting properties of the microfluidic channels are crucial factors for droplet generation, we also briefly describe typical device fabrication methods in droplet based microfluidics. Examples of applications and reaction schemes which rely on the discussed manipulation techniques are also presented, such as the fabrication of special materials and biophysical experiments.

  2. A Microfluidic Cell Concentrator

    Science.gov (United States)

    Warrick, Jay; Casavant, Ben; Frisk, Megan; Beebe, David

    2010-01-01

    Cell concentration via centrifugation is a ubiquitous step in many cell culture procedures. At the macroscale, centrifugation suffers from a number of limitations particularly when dealing with small numbers of cells (e.g., less than 50,000). On the other hand, typical microscale methods for cell concentration can affect cell physiology and bias readouts of cell behavior and function. In this paper, we present a microfluidic concentrator device that utilizes the effects of gravity to allow cells to gently settle out of a suspension into a collection region without the use of specific adhesion ligands. Dimensional analysis was performed to compare different device designs and was verified with flow modeling to optimize operational parameters. We are able to concentrate low-density cell suspensions in a microfluidic chamber, achieving a cell loss of only 1.1 ± 0.6% (SD, n=7) with no observed loss during a subsequent cell staining protocol which incorporates ~36 complete device volume replacements. This method provides a much needed interface between rare cell samples and microfluidic culture assays. PMID:20843010

  3. Microfluidics with fluid walls.

    Science.gov (United States)

    Walsh, Edmond J; Feuerborn, Alexander; Wheeler, James H R; Tan, Ann Na; Durham, William M; Foster, Kevin R; Cook, Peter R

    2017-10-10

    Microfluidics has great potential, but the complexity of fabricating and operating devices has limited its use. Here we describe a method - Freestyle Fluidics - that overcomes many key limitations. In this method, liquids are confined by fluid (not solid) walls. Aqueous circuits with any 2D shape are printed in seconds on plastic or glass Petri dishes; then, interfacial forces pin liquids to substrates, and overlaying an immiscible liquid prevents evaporation. Confining fluid walls are pliant and resilient; they self-heal when liquids are pipetted through them. We drive flow through a wide range of circuits passively by manipulating surface tension and hydrostatic pressure, and actively using external pumps. Finally, we validate the technology with two challenging applications - triggering an inflammatory response in human cells and chemotaxis in bacterial biofilms. This approach provides a powerful and versatile alternative to traditional microfluidics.The complexity of fabricating and operating microfluidic devices limits their use. Walsh et al. describe a method in which circuits are printed as quickly and simply as writing with a pen, and liquids in them are confined by fluid instead of solid walls.

  4. Microfluidic desalination : capacitive deionization on chip for microfluidic sample preparation

    NARCIS (Netherlands)

    Roelofs, Susan Helena

    2015-01-01

    The main aim of the work described in this thesis is to implement the desalination technique capacitive deionization (CDI) on a microfluidic chip to improve the reproducibility in the analysis of biological samples for drug development. Secondly, microfluidic CDI allows for the in situ study of ion

  5. Manufacturing of a graphite calorimeter at Yazd Radiation Processing Center

    International Nuclear Information System (INIS)

    Ziaie, F.

    2004-01-01

    In this work, a few quasi-adiabatic graphite calorimeters of different dimensions are described. The calorimeters have been manufactured by ourselves and studied for accurate absorbed dose measurements in 10 MeV electron beam. In order to prove the accuracy and reliability of dose measurements with the use of self designed graphite calorimeters (SCD), an inter comparison study was performed on these calorimeters and Risoe graphite calorimeters (SC,standard calorimeter) at different doses by using Rhodothron accelerator. The comparison shows conclusively of the optimal size, the results agreeing with those obtained with the Sc within 1%. (author)

  6. A highly sensitive and specific assay for vertebrate collagenase

    International Nuclear Information System (INIS)

    Sodek, J.; Hurum, S.; Feng, J.

    1981-01-01

    A highly sensitive and specific assay for vertebrate collagenase has been developed using a [ 14 C]-labeled collagen substrate and a combination of SDS-PAGE (sodium dodecyl sulfate-polyacrylamide gel electrophoresis) and fluorography to identify and quantitate the digestion products. The assay was sufficiently sensitive to permit the detection and quantitation of collagenase activity in 0.1 μl of gingival sulcal fluid, and in samples of cell culture medium without prior concentration. The assay has also been used to detect the presence of inhibitors of collagenolytic enzymes in various cell culture fluids. (author)

  7. Highly Sensitive Flexible Magnetic Sensor Based on Anisotropic Magnetoresistance Effect.

    Science.gov (United States)

    Wang, Zhiguang; Wang, Xinjun; Li, Menghui; Gao, Yuan; Hu, Zhongqiang; Nan, Tianxiang; Liang, Xianfeng; Chen, Huaihao; Yang, Jia; Cash, Syd; Sun, Nian-Xiang

    2016-11-01

    A highly sensitive flexible magnetic sensor based on the anisotropic magnetoresistance effect is fabricated. A limit of detection of 150 nT is observed and excellent deformation stability is achieved after wrapping of the flexible sensor, with bending radii down to 5 mm. The flexible AMR sensor is used to read a magnetic pattern with a thickness of 10 μm that is formed by ferrite magnetic inks. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. High sensitivity on-line monitor for radioactive effluent

    Energy Technology Data Exchange (ETDEWEB)

    Sasaki, Toshimi [Tohoku Electric Power Co. Ltd., Sendai (Japan); Ishizuka, Akira; Abe, Eisuke; Inoue, Yasuhiko; Fujii, Masaaki; Kitaguchi, Hiroshi; Doi, Akira

    1983-04-01

    A new approach for a highly sensitive effluent monitor is presented. The free flow type monitor, which consists of a straightener, nozzle, monitoring section and ..gamma..-ray detector, is demonstrated to be effective in providing long term stability. The 160 start-and-stop cycles of effluent discharge were repeated in a 120-h testing period. Results showed a background increase was not observed for the free flow type monitor. The background count rate was calibrated to the lowest detection limit to be 2.2 x 10/sup -2/ Bq/ml for a 300 s measurement time.

  9. The spaghetti calorimeter. Research, development, application

    Energy Technology Data Exchange (ETDEWEB)

    Scheel, C V

    1994-12-22

    The Spaghetti Calorimeter (SPACAL) is a detector intended primarily for the energy measurement of high-energy particles, but also provides spatial information and particle identification. It is a sampling calorimeter composed of plastic scintillating fibers, oriented in the direction of the particle, embedded in lead. The scintillation light is read out by photomultipliers, which are coupled to bunches of fibers through light guides, each forming a tower. It was developed as an electromagnetic (e.m.) and compensating hadronic calorimeter for use in future multi-TeV collider experiments. The largest prototype was installed for an alternative application as an hadronic calorimeter in the WA89 experiment, where it is used for the detection of neutrons resulting from {Sigma} decays. The basic concepts behind calorimetry are discussed in detail. Several prototypes were tested in beams of electrons and pions with energies up to 150 GeV. Resonable e.m. energy resolution, at {sigma}/E=12.9%/{radical}E[GeV]+1.23%, was measured. Excellent hadronic energy resolution was found, at 30.6%/{radical}E[GeV]+1.0%, but the calorimeter was found to be slightly undercompensating with e/h=1.15. The position of the shower barycenter for both electrons and pions was easily found according to the relative energy deposits in the calorimeter towers. The calorimeter was also found to be able to provide effective discrimination between electrons and hadrons. The performance of SPACAL in the WA89 experiment at the Omega spectrometer at CERN was studied with the reconstruction of beam {Sigma}{sup -}particles via its decay {Sigma}{sup -}{yields}n{pi}{sup -}. Details of the calibration of SPACAL with electrons and protons are presented. (orig.).

  10. The spaghetti calorimeter. Research, development, application

    International Nuclear Information System (INIS)

    Scheel, C.V.

    1994-01-01

    The Spaghetti Calorimeter (SPACAL) is a detector intended primarily for the energy measurement of high-energy particles, but also provides spatial information and particle identification. It is a sampling calorimeter composed of plastic scintillating fibers, oriented in the direction of the particle, embedded in lead. The scintillation light is read out by photomultipliers, which are coupled to bunches of fibers through light guides, each forming a tower. It was developed as an electromagnetic (e.m.) and compensating hadronic calorimeter for use in future multi-TeV collider experiments. The largest prototype was installed for an alternative application as an hadronic calorimeter in the WA89 experiment, where it is used for the detection of neutrons resulting from Σ decays. The basic concepts behind calorimetry are discussed in detail. Several prototypes were tested in beams of electrons and pions with energies up to 150 GeV. Resonable e.m. energy resolution, at σ/E=12.9%/√E[GeV]+1.23%, was measured. Excellent hadronic energy resolution was found, at 30.6%/√E[GeV]+1.0%, but the calorimeter was found to be slightly undercompensating with e/h=1.15. The position of the shower barycenter for both electrons and pions was easily found according to the relative energy deposits in the calorimeter towers. The calorimeter was also found to be able to provide effective discrimination between electrons and hadrons. The performance of SPACAL in the WA89 experiment at the Omega spectrometer at CERN was studied with the reconstruction of beam Σ - particles via its decay Σ - →nπ - . Details of the calibration of SPACAL with electrons and protons are presented. (orig.)

  11. A new ultrasensitive scanning calorimeter.

    Science.gov (United States)

    Plotnikov, V V; Brandts, J M; Lin, L N; Brandts, J F

    1997-08-01

    A new ultrasensitive differential scanning calorimeter is described, having a number of novel features arising from integration between hardware and software. It is capable of high performance in either a scanning or isothermal mode of operation. Upscanning is carried out adiabatically while downscanning is nonadiabatic. By using software-controlled signals sent continuously to appropriate hardware devices, it is possible to improve adiabaticity and constancy of scan rate through use of empirical prerun information stored in memory rather than by using feedback systems which respond in real time and generate thermal noise. Also, instrument response time is software-selectable, maximizing performance for both slow- and fast-transient systems. While these and other sophisticated functionalities have been introduced into the instrument to improve performance and data analysis, they are virtually invisible and add no additional complexities into operation of the instrument. Noise and baseline repeatability are an order of magnitude better than published raw data from other instruments so that high-quality results can be obtained on protein solutions, for example, using as little as 50 microg of protein in the sample cell.

  12. Tritium calorimeter setup and operation

    International Nuclear Information System (INIS)

    Rodgers, David E.

    2002-01-01

    The LBNL tritium calorimeter is a stable instrument capable of measuring tritium with a sensitivity of 25 Ci. Measurement times range from 8-hr to 7-days depending on the thermal conductivity and mass of the material being measured. The instrument allows accurate tritium measurements without requiring that the sample be opened and subsampled, thus reducing personnel exposure and radioactive waste generation. The sensitivity limit is primarily due to response shifts caused by temperature fluctuation in the water bath. The fluctuations are most likely a combination of insufficient insulation from ambient air and precision limitations in the temperature controller. The sensitivity could probably be reduced to below 5 Ci if the following improvements were made: (1) Extend the external insulation to cover the entire bath and increase the top insulation. (2) Improve the seal between the air space above the bath and the outside air to reduce evaporation. This will limit the response drift as the water level drops. (3) Install an improved temperature controller, preferably with a built in chiller, capable of temperature control to ±0.001 C

  13. Highly sensitive detection of urinary cadmium to assess personal exposure

    Energy Technology Data Exchange (ETDEWEB)

    Argun, Avni A.; Banks, Ashley M.; Merlen, Gwendolynne; Tempelman, Linda A. [Giner, Inc., 89 Rumford Ave., Newton 02466, MA United States (United States); Becker, Michael F.; Schuelke, Thomas [Fraunhofer USA – CCL, 1449 Engineering Research Ct., East Lansing 48824, MI (United States); Dweik, Badawi M., E-mail: bdweik@ginerinc.com [Giner, Inc., 89 Rumford Ave., Newton 02466, MA United States (United States)

    2013-04-22

    Highlights: ► An electrochemical sensor capable of detecting cadmium at parts-per-billion levels in urine. ► A novel fabrication method for Boron-Doped Diamond (BDD) ultramicroelectrode (UME) arrays. ► Unique combination of BDD UME arrays and a differential pulse voltammetry algorithm. ► High sensitivity, high reproducibility, and very low noise levels. ► Opportunity for portable operation to assess on-site personal exposure. -- Abstract: A series of Boron-Doped Diamond (BDD) ultramicroelectrode arrays were fabricated and investigated for their performance as electrochemical sensors to detect trace level metals such as cadmium. The steady-state diffusion behavior of these sensors was validated using cyclic voltammetry followed by electrochemical detection of cadmium in water and in human urine to demonstrate high sensitivity (>200 μA ppb{sup −1} cm{sup −2}) and low background current (<4 nA). When an array of ultramicroelectrodes was positioned with optimal spacing, these BDD sensors showed a sigmoidal diffusion behavior. They also demonstrated high accuracy with linear dose dependence for quantification of cadmium in a certified reference river water sample from the U.S. National Institute of Standards and Technology (NIST) as well as in a human urine sample spiked with 0.25–1 ppb cadmium.

  14. Towards highly sensitive strain sensing based on nanostructured materials

    International Nuclear Information System (INIS)

    Dao, Dzung Viet; Nakamura, Koichi; Sugiyama, Susumu; Bui, Tung Thanh; Dau, Van Thanh; Yamada, Takeo; Hata, Kenji

    2010-01-01

    This paper presents our recent theoretical and experimental study of piezo-effects in nanostructured materials for highly sensitive, high resolution mechanical sensors. The piezo-effects presented here include the piezoresistive effect in a silicon nanowire (SiNW) and single wall carbon nanotube (SWCNT) thin film, as well as the piezo-optic effect in a Si photonic crystal (PhC) nanocavity. Firstly, the electronic energy band structure of the silicon nanostructure is discussed and simulated by using the First-Principles Calculations method. The result showed a remarkably different energy band structure compared with that of bulk silicon. This difference in the electronic state will result in different physical, chemical, and therefore, sensing properties of silicon nanostructures. The piezoresistive effects of SiNW and SWCNT thin film were investigated experimentally. We found that, when the width of ( 110 ) p-type SiNW decreases from 500 to 35 nm, the piezoresistive effect increases by more than 60%. The longitudinal piezoresistive coefficient of SWCNT thin film was measured to be twice that of bulk p-type silicon. Finally, theoretical investigations of the piezo-optic effect in a PhC nanocavity based on Finite Difference Time Domain (FDTD) showed extremely high resolution strain sensing. These nanostructures were fabricated based on top-down nanofabrication technology. The achievements of this work are significant for highly sensitive, high resolution and miniaturized mechanical sensors

  15. Hadron showers in a highly granular calorimeter

    Energy Technology Data Exchange (ETDEWEB)

    Lutz, Benjamin

    2010-11-15

    A future electron-positron collider like the planned International Linear Collider (ILC) needs excellent detectors to exploit the full physics potential. Different detector concepts have been evaluated for the ILC and two concepts on the particle-flow approach were validated. To make particle-flow work, a new type of imaging calorimeters is necessary in combination with a high performance tracking system, to be able to track the single particles through the full detector system. These calorimeters require an unprecedented level of both longitudinal and lateral granularity. Several calorimeter technologies promise to reach the required readout segmentation and are currently studied. This thesis addresses one of these: The analogue hadron calorimeter technology. It combines work on the technological aspects of a highly granular calorimeter with the study of hadron shower physics. The analogue hadron calorimeter technology joins a classical scintillator-steel sandwich design with a modern photo-sensor technology, the silicon photomultiplier (SiPM). The SiPM is a millimetre sized, magnetic field insensitive, and low cost photo-sensor, that opens new possibilities in calorimeter design. This thesis outlines the working principle and characteristics of these devices. The requirements for an application specific integrated circuit (ASIC) to read the SiPM are discussed; the performance of a prototype chip for SiPM readout, the SPIROC, is quantified. Also the SiPM specific reconstruction of a multi-thousand channel prototype calorimeter, the CALICE AHCAL, is explained; the systematic uncertainty of the calibration method is derived. The AHCAL does not only offer a test of the calorimeter technology, it also allows to record hadron showers with an unprecedented level of details. Test-beam measurements have been performed with the AHCAL and provide a unique sample for the development of novel analysis techniques and the validation of hadron shower simulations. A method to

  16. Hadron showers in a highly granular calorimeter

    International Nuclear Information System (INIS)

    Lutz, Benjamin

    2010-11-01

    A future electron-positron collider like the planned International Linear Collider (ILC) needs excellent detectors to exploit the full physics potential. Different detector concepts have been evaluated for the ILC and two concepts on the particle-flow approach were validated. To make particle-flow work, a new type of imaging calorimeters is necessary in combination with a high performance tracking system, to be able to track the single particles through the full detector system. These calorimeters require an unprecedented level of both longitudinal and lateral granularity. Several calorimeter technologies promise to reach the required readout segmentation and are currently studied. This thesis addresses one of these: The analogue hadron calorimeter technology. It combines work on the technological aspects of a highly granular calorimeter with the study of hadron shower physics. The analogue hadron calorimeter technology joins a classical scintillator-steel sandwich design with a modern photo-sensor technology, the silicon photomultiplier (SiPM). The SiPM is a millimetre sized, magnetic field insensitive, and low cost photo-sensor, that opens new possibilities in calorimeter design. This thesis outlines the working principle and characteristics of these devices. The requirements for an application specific integrated circuit (ASIC) to read the SiPM are discussed; the performance of a prototype chip for SiPM readout, the SPIROC, is quantified. Also the SiPM specific reconstruction of a multi-thousand channel prototype calorimeter, the CALICE AHCAL, is explained; the systematic uncertainty of the calibration method is derived. The AHCAL does not only offer a test of the calorimeter technology, it also allows to record hadron showers with an unprecedented level of details. Test-beam measurements have been performed with the AHCAL and provide a unique sample for the development of novel analysis techniques and the validation of hadron shower simulations. A method to

  17. The H1 liquid argon calorimeter system

    International Nuclear Information System (INIS)

    Andrieu, B.; Babayev, A.; Ban, J.

    1993-06-01

    The liquid argon calorimeter of the H1 detector presently taking data at the HERA ep - collider at DESY, Hamburg, is described here. The main physics requirements and the most salient design features relevant to this calorimeter are given. The aim to have smooth and hermetic calorimetric coverage over the polar angular range 4 ≤ θ ≤ 154 is achieved by a single liquid argon cryostat containing calorimeter stacks structured in wheels and octants for easy handling. The absorber materials used are lead in the electromagnetic part and stainless steel in the hadronic part. The read-out system is pipelined to reduce the dead time induced by the high trigger rate expected at the HERA collider where consecutive bunches are separated in time by 96 ns. The main elements of the calorimeter, such as the cryostat, with its associated cryogenics, the stack modules, the read-out, calibration and trigger electronics as well as the data acquisition system are described. Performance results from data taken in calibration runs with full size H1 calorimeter stacks at a CERN test beam, as well as results from data collected with the complete H1 detector using cosmic rays during the initial phase of ep operations are presented. The observed energy resolutions and linearities are well in agreement with the requirements. (orig.)

  18. A water flow calorimeter calibration system

    International Nuclear Information System (INIS)

    Ullrich, F.T.

    1983-01-01

    Neutral beam systems are instrumented by several water flow calorimeter systems, and some means is needed to verify the accuracy of such systems and diagnose their failures. This report describes a calibration system for these calorimeters. The calibrator consists of two 24 kilowatt circulation water heaters, with associated controls and instrumentation. The unit can supply power from 0 to 48 kW in five coarse steps and one fine range. Energy is controlled by varying the power and the time of operation of the heaters. The power is measured by means of precision power transducers, and the energy is measured by integrating the power with respect to time. The accuracy of the energy measurement is better than 0.5% when the power supplied is near full scale, and the energy resolution is better than 1 kilojoule. The maximum energy delivered is approximately 50 megajoules. The calorimetry loop to be calibrated is opened, and the calibrator is put in series with the calorimeter heat source. The calorimeter is then operated in its normal fashion, with the calibrator used as the heat source. The calibrator can also be used in a stand alone mode to calibrate calorimeter sensors removed from systems

  19. LHCb Calorimeter modules arrive at CERN

    CERN Multimedia

    2002-01-01

    Two of the three components of the LHCb Calorimeter system have started to arrive from Russia. Members of the LHCb Calorimeter group with the ECAL and HCAL modules that have just arrived at CERN. The first two of the 56 Hadron Calorimeter (HCAL) modules and 1200 of the 3300 modules of the Electromagnetic Calorimeter (ECAL) have reached CERN from Russia. The third part of the system, the Preshower detector, is still being prepared in Russia. The calorimeter system identifies and triggers on high-energy particles, namely electrons, hadrons and photons by measuring their positions and energies. The HCAL is going to be a pure trigger device. The ECAL will also be used in the triggering, but in addition it will reconstruct neutral pions and photons from B meson decays. One of the major aims of the LHCb experiment is to study CP violation through B meson decays including Bs mesons with high statistics in different decay modes. CP violation (violation of charge and parity) is necessary to explain why the Universe...

  20. Performance of the ATLAS hadronic Tile calorimeter

    CERN Document Server

    Bartos, Pavol; The ATLAS collaboration

    2016-01-01

    Performance of the ATLAS hadronic Tile calorimeter The Tile Calorimeter (TileCal) of the ATLAS experiment at the LHC is the central hadronic calorimeter designed for energy reconstruction of hadrons, jets, tau-particles and missing transverse energy. TileCal is a scintillator-steel sampling calorimeter and it covers the region of pseudorapidity < 1.7. The scintillation light produced in the scintillator tiles is transmitted by wavelength shifting fibers to photomultiplier tubes (PMTs). The analog signals from the PMTs are amplified, shaped and digitized by sampling the signal every 25 ns. The TileCal frontend electronics reads out the signals produced by about 10000 channels measuring energies ranging from ~30 MeV to ~2 TeV. Each stage of the signal production from scintillation light to the signal reconstruction is monitored and calibrated. The performance of the calorimeter have been studied in-situ employing cosmic ray muons and a large sample of proton-proton collisions acquired during the operations o...

  1. ATLAS Tile calorimeter calibration and monitoring systems

    Science.gov (United States)

    Chomont, Arthur; ATLAS Collaboration

    2017-11-01

    The ATLAS Tile Calorimeter (TileCal) is the central section of the hadronic calorimeter of the ATLAS experiment and provides important information for reconstruction of hadrons, jets, hadronic decays of tau leptons and missing transverse energy. This sampling calorimeter uses steel plates as absorber and scintillating tiles as active medium. The light produced by the passage of charged particles is transmitted by wavelength shifting fibres to photomultiplier tubes (PMTs), located on the outside of the calorimeter. The readout is segmented into about 5000 cells (longitudinally and transversally), each of them being read out by two PMTs in parallel. To calibrate and monitor the stability and performance of each part of the readout chain during the data taking, a set of calibration systems is used. The TileCal calibration system comprises cesium radioactive sources, Laser and charge injection elements, and allows for monitoring and equalization of the calorimeter response at each stage of the signal production, from scintillation light to digitization. Based on LHC Run 1 experience, several calibration systems were improved for Run 2. The lessons learned, the modifications, and the current LHC Run 2 performance are discussed.

  2. MICROFLUIDIC COMPONENT CAPABLE OF SELF-SEALING

    DEFF Research Database (Denmark)

    2009-01-01

    A microfluidic component (100) for building a microfluidic system is provided. The microfluidic component (100) can be mounted on a microf luidic breadboard (202) in a manner that allows it to be connected to other microfluidic components (204, 206) without the requirement of additional devices....... The microfluidic component (100) comprises at least one flexible tube piece (102) for transporting a fluid. The microfluidic component (100) also comprises means for applying and maintaining pressure (104) between the flexible tube piece (102) and a tube piece (208, 210) housed in another microfluidic component...

  3. The Dynamic Characteristic Analysis of Mini Gamma Calorimeter

    International Nuclear Information System (INIS)

    Setiyanto

    2004-01-01

    The gamma calorimeter is a facility to measure the gamma heating in the nuclear reactor. The dimensions of the conventional calorimeters are in general too large, that is an inconvenience if those calorimeters will be applied in the high temperature reactor as a nuclear power plant. To avoid that inconvenience, it is necessary to propose the innovation on the feature of the existing calorimeter. The basic idea of the innovation is to create the small type of calorimeter without the absorbed material. The last analysis was realized to determine of the static calorimeter characteristic or sensitivities as a function of the dimension and the material of gas isolations. Based on those results, the analyses is reasonably to be continued to determine the dynamic characteristic or period of calorimeter. The analysis was performed using the finite difference method, two dimension simplified. It can be concluded that the mini gamma calorimeter proposed is reasonable to be made. (author)

  4. To the calculation of energy resolution of ionization calorimeter

    International Nuclear Information System (INIS)

    Uchajkin, V.V.; Lagutin, A.A.

    1976-01-01

    The question of energy resolution of the ionization calorimeter is considered analytically. A method is discussed for calculating the probability characteristics (mean value and dispersion) of energy losses of an electron-photon shower by ionization in the calorimeter volume

  5. Performance of a shashlik calorimeter at LEP II

    CERN Document Server

    Ferrari, P; Klovning, A; Maeland, O A; Stugu, B; Benvenuti, Alberto C; Giordano, V; Guerzoni, M; Navarria, Francesco Luigi; Verardi, M G; Camporesi, T; Bozzo, M; Cereseto, R; Barreira, G; Espirito-Santo, M C; Maio, A; Onofre, A; Peralta, L; Pimenta, M; Tomé, B; Carling, H; Falk, E; Hedberg, V; Jarlskog, G; Kronkvist, I J; Bonesini, M; Chignoli, F; Gumenyuk, S A; Leoni, R; Mazza, R; Negri, P; Paganoni, M; Petrovykh, L P; Terranova, F; Dharmasiri, D R; Nossum, B; Read, A L; Skaali, T B; Castellani, L; Pegoraro, M; Fenyuk, A; Guz, Yu; Karyukhin, A N; Konoplyannikov, A K; Obraztsov, V F; Shalanda, N A; Vlasov, E; Zaitsev, A; Bigi, M; Cassio, V; Gamba, D; Migliore, E; Romero, A; Simonetti, L; Torassa, E; Trapani, P P; Bari, M D; Della Ricca, G; Lanceri, L; Poropat, P; Prest, M; Vallazza, E

    1999-01-01

    The small angle tile calorimeter (STIC) is a sampling lead- scintillator calorimeter, built with "shashlik" technique. Results are presented from extensive studies of the detector performance at LEP. (5 refs).

  6. Detailed GEANT description of the SDC central calorimeters

    International Nuclear Information System (INIS)

    Glagolev, V.V.; Li, W.

    1994-01-01

    This article represents the very detailed simulation model of the SDC central calorimeters and some results which were obtained using that model. The central calorimeters structure was coded on the GEANT 3.15 base in the frame of the SDCSIM environment. The SDCSIM is the general shell for simulation of the SDC set-up. The calorimeters geometry has been coded according to the FNAL and ANL engineering drawings and engineering data file. SDC central calorimeters detailed description is extremely useful for different simulation tasks, for fast simulation program parameters tuning, for different geometry especially studying (local response nonuniformity from bulkheads in the e.m. calorimeter and from coil supports and many others) and for the interpretation of the experimental data from the calorimeters. This simulation model is very useful for tasks of the test beam modules calorimeter calibration and for calorimeter in situ calibration. 3 refs., 8 figs

  7. Calorimeter based detectors for high energy hadron colliders

    International Nuclear Information System (INIS)

    Marx, M.D.; Rijssenbeek, M.

    1990-01-01

    This report discusses the following topics: the central calorimeter; and installation; commissioning; and calorimeter beam tests; the central drift chamber; cosmic ray and beam tests; chamber installation and commissioning; and software development; and SSC activities: the EMPACT project

  8. Indirect measurement of the magnetocaloric effect using a novel differential scanning calorimeter with magnetic field.

    Science.gov (United States)

    Jeppesen, S; Linderoth, S; Pryds, N; Kuhn, L Theil; Jensen, J Buch

    2008-08-01

    A simple and high-sensitivity differential scanning calorimeter (DSC) unit operating under magnetic field has been built for indirect determination of the magnetocaloric effect. The principle of the measuring unit in the calorimeter is based on Peltier elements as heat flow sensors. The high sensitivity of the apparatus combined with a suitable calibration procedure allows very fast and accurate heat capacity measurements under magnetic field to be made. The device was validated from heat capacity measurements for the typical DSC reference material gallium (Ga) and a La(0.67)Ca(0.33)MnO(3) manganite system and the results were highly consistent with previous reported data for these materials. The DSC has a working range from 200 to 340 K and has been tested in magnetic fields reaching 1.8 T. The signal-to-noise ratio is in the range of 10(2)-10(3) for the described experiments. Finally the results have been compared to results from a Quantum Design(R) physical properties measuring system. The configuration of the system also has the advantage of being able to operate with other types of magnets, e.g., permanent magnets or superconducting coils, as well as the ability to be expanded to a wider temperature range.

  9. STATUS OF THE ATLAS LIQUID ARGON CALORIMETER AND ITS PERFORMANCE

    CERN Document Server

    Berillari, T; The ATLAS collaboration

    2011-01-01

    The liquid argon (LAr) calorimeters are used in ATLAS for all electromagnetic and for hadron calorimetry. The LAr calorimeter system consists of an electromagnetic barrel calorimeter and two endcaps with electromagnetic, hadronic and forward calorimeters. The latest status of the detector as well as problems and solutions addressed during the last years will be presented. Aspects of operation of a large detector over a long time period will be summarized and selected topics showing the performance of the detector will be shown.

  10. Feasibility of a Mound-designed transportable calorimeter

    International Nuclear Information System (INIS)

    Duff, M.F.; Fellers, C.L.

    1979-01-01

    The feasibility of operating a Mound twin resistance bridge calorimeter outside a temperature-controlled water bath was demonstrated. An existing calorimeter was retrofit with two additional jackets through which water was transferred from an external reservoir. Comparison of test results collected before and after the retrofit indicated that the calorimeter performance was not degraded by this modification. Similarly designed calorimeters have potential applications in laboratories where equipment space is limited for inspectors who are required to transport their assay instrumentation

  11. Microfluidic Cell Culture Device

    Science.gov (United States)

    Takayama, Shuichi (Inventor); Cabrera, Lourdes Marcella (Inventor); Heo, Yun Seok (Inventor); Smith, Gary Daniel (Inventor)

    2014-01-01

    Microfluidic devices for cell culturing and methods for using the same are disclosed. One device includes a substrate and membrane. The substrate includes a reservoir in fluid communication with a passage. A bio-compatible fluid may be added to the reservoir and passage. The reservoir is configured to receive and retain at least a portion of a cell mass. The membrane acts as a barrier to evaporation of the bio-compatible fluid from the passage. A cover fluid may be added to cover the bio-compatible fluid to prevent evaporation of the bio-compatible fluid.

  12. Microfluidic Scintillation Detectors

    CERN Multimedia

    Microfluidic scintillation detectors are devices of recent introduction for the detection of high energy particles, developed within the EP-DT group at CERN. Most of the interest for such technology comes from the use of liquid scintillators, which entails the possibility of changing the active material in the detector, leading to an increased radiation resistance. This feature, together with the high spatial resolution and low thickness deriving from the microfabrication techniques used to manufacture such devices, is desirable not only in instrumentation for high energy physics experiments but also in medical detectors such as beam monitors for hadron therapy.

  13. Spatial manipulation with microfluidics

    Directory of Open Access Journals (Sweden)

    Benjamin eLin

    2015-04-01

    Full Text Available Biochemical gradients convey information through space, time, and concentration, and are ultimately capable of spatially resolving distinct cellular phenotypes, such as differentiation, proliferation, and migration. How these gradients develop, evolve, and function during development, homeostasis, and various disease states is a subject of intense interest across a variety of disciplines. Microfluidic technologies have become essential tools for investigating gradient sensing in vitro due to their ability to precisely manipulate fluids on demand in well controlled environments at cellular length scales. This minireview will highlight their utility for studying gradient sensing along with relevant applications to biology.

  14. Laser calibration of the ATLAS Tile Calorimeter

    CERN Document Server

    Di Gregorio, Giulia; The ATLAS collaboration

    2017-01-01

    High performance stability of the ATLAS Tile calorimeter is achieved with a set of calibration procedures. One step of the calibrtion procedure is based on measurements of the response stability to laser excitation of the photomultipliers (PMTs) that are used to readout the calorimeter cells. A facility to study in lab the PMT stability response is operating in the PISA-INFN laboratories since 2015. Goals of the test in lab are to study the time evolution of the PMT response to reproduce and to understand the origin of the resonse drifts seen with the PMT mounted on the Tile calorimeter in its normal operation during LHC run I and run II. A new statistical approach was developed to measure the drift of the absolute gain. This approach was applied to both the ATLAS laser calibration data and to the data collected in the Pisa local laboratory. The preliminary results from these two studies are shown.

  15. Optics robustness of the ATLAS Tile Calorimeter

    CERN Document Server

    Costa Batalha Pedro, Rute; The ATLAS collaboration

    2018-01-01

    TileCal, the central hadronic calorimeter of the ATLAS detector is composed of plastic scintillators interleaved by iron plates, and wavelength shifting optical fibres. The optical properties of these components are known to suffer from natural ageing and degrade due to exposure to radiation. The calorimeter was designed for 10 years of LHC operating at the design luminosity of $10^{34}$ cm$^{-1}$s$^{-1}$. Irradiation tests of scintillators and fibres shown that their light yield decrease about 10 for the maximum dose expected after the 10 years of LHC operation. The robustness of the TileCal optics components is evaluated using the calibration systems of the calorimeter: Cs-137 gamma source, laser light, and integrated photomultiplier signals of particles from collisions. It is observed that the loss of light yield increases with exposure to radiation as expected. The decrease in the light yield during the years 2015-2017 corresponding to the LHC Run 2 will be reported.

  16. Vacuum-jacketed hydrofluoric acid solution calorimeter

    Science.gov (United States)

    Robie, R.A.

    1965-01-01

    A vacuum-jacketed metal calorimeter for determining heats of solution in aqueous HF was constructed. The reaction vessel was made of copper and was heavily gold plated. The calorimeter has a cooling constant of 0.6 cal-deg -1-min-1, approximately 1/4 that of the air-jacketed calorimeters most commonly used with HF. It reaches equilibrium within 10 min after turning off the heater current. Measurements of the heat of solution of reagent grade KCl(-100 mesh dried 2 h at 200??C) at a mole ratio of 1 KCl to 200 H2O gave ??H = 4198??11 cal at 25??C. ?? 1965 The American Institute of Physics.

  17. ATLAS Tile calorimeter calibration and monitoring systems

    CERN Document Server

    Boumediene, Djamel Eddine; The ATLAS collaboration

    2017-01-01

    The ATLAS Tile Calorimeter (TileCal) is the central section of the hadronic calorimeter of the ATLAS experiment and provides important information for reconstruction of hadrons, jets, hadronic decays of tau leptons and missing transverse energy. This sampling calorimeter uses steel plates as absorber and scintillating tiles as active medium. The light produced by the passage of charged particles is transmitted by wavelength shifting fibres to photomultiplier tubes (PMTs). PMT signals are then digitized at 40 MHz and stored on detector and are only transferred off detector once the first level trigger acceptance has been confirmed. The readout is segmented into about 5000 cells (longitudinally and transversally), each of them being read out by two PMTs in parallel. To calibrate and monitor the stability and performance of each part of the readout chain, a set of calibration systems is used. The TileCal calibration system comprises Cesium radioactive sources, laser, charge injection elements and an integrator b...

  18. Laser Calibration of the ATLAS Tile Calorimeter

    CERN Document Server

    Di Gregorio, Giulia; The ATLAS collaboration

    2017-01-01

    High performance stability of the ATLAS Tile Calorimeter is achieved with a set of calibration procedures. One step of the calibration procedure is based on measurements of the response stability to laser excitation of the PMTs that are used to readout the calorimeter cells. A facility to study in lab the PMT stability response is operating in the PISA-INFN laboratories since 2015. Goals of the tests in lab are to study the time evolution of the PMT response to reproduce and to understand the origin of the response drifts seen with the PMT mounted on the Tile calorimeter in its normal operating during LHC run I and run II. A new statistical approach was developed to measure drift of the absolute gain. This approach was applied to both the ATLAS laser calibration data and to data collected in the Pisa local laboratory. The preliminary results from these two studies are shown.

  19. Towards Multiplex Molecular Diagnosis—A Review of Microfluidic Genomics Technologies

    Directory of Open Access Journals (Sweden)

    Ismail Hussain Kamal Basha

    2017-08-01

    Full Text Available Highly sensitive and specific pathogen diagnosis is essential for correct and timely treatment of infectious diseases, especially virulent strains, in people. Point-of-care pathogen diagnosis can be a tremendous help in managing disease outbreaks as well as in routine healthcare settings. Infectious pathogens can be identified with high specificity using molecular methods. A plethora of microfluidic innovations in recent years have now made it increasingly feasible to develop portable, robust, accurate, and sensitive genomic diagnostic devices for deployment at the point of care. However, improving processing time, multiplexed detection, sensitivity and limit of detection, specificity, and ease of deployment in resource-limited settings are ongoing challenges. This review outlines recent techniques in microfluidic genomic diagnosis and devices with a focus on integrating them into a lab on a chip that will lead towards the development of multiplexed point-of-care devices of high sensitivity and specificity.

  20. Development of an underwater high sensitivity Cherenkov detector: Sea Urchin

    International Nuclear Information System (INIS)

    Camerini, U.; McGibney, D.; Roberts, A.

    1982-01-01

    The need for a high gain, high sensitivity Cherenkov light sensor to be used in a deep underwater muon and neutrino detector (DUMAND) array has led to the design of the Sea Urchin detector. In this design a spherical photocathode PMTis optically coupled through a glass hemisphere to a large number of glass spines, each of which is filled with a wavelength-shifting (WLS) solution of a high quantum efficiency phosphor. The Cherenkov radiation is absorbed in the spine, isotropically re-radiated at a longer wavelength, and a fraction of the fluorescent light is internally reflected in the spine, and guided to the photomultiplier concentrically located in the glass hemisphere. Experiments measuring the optical characteristics of the spines and computer programs simulating light transformation and detection cross sections are described. Overall optical gains in the range 5-10 are achieved. The WLS solution is inexpensive, and may have other applications. (orig.)

  1. High sensitivity tests of the standard model for electroweak interactions

    International Nuclear Information System (INIS)

    Koetke, D.D.

    1992-01-01

    The work done on this project was focussed mainly on LAMPF experiment E969 known as the MEGA experiment, a high sensitivity search for the lepton family number violating decay μ → eγ to a sensitivity which, measured in terms of the branching ratio, BR = [μ→eγ]/[μ→e ν μ ν e ] ∼10 -13 is over two orders of magnitude better than previously reported values. The work done on MEGA during this period was divided between that done at Valparaiso University and that done at LAMPF. In addition, some contributions were made to a proposal to the LAMPF PAC to perform a precision measurement of the Michel ρ parameter, described below

  2. High sensitivity tests of the standard model for electroweak interactions

    International Nuclear Information System (INIS)

    1994-01-01

    The work done on this project focused on two LAMPF experiments. The MEGA experiment is a high-sensitivity search for the lepton family number violating decay μ → eγ to a sensitivity which, measured in terms of the branching ratio, BR = [μ → eγ]/[μ eν μ ν e ] ∼ 10 -13 , will be over two orders of magnitude better than previously reported values. The second is a precision measurement of the Michel ρ parameter from the positron energy spectrum of μ → eν μ ν e to test the predictions V-A theory of weak interactions. In this experiment the uncertainty in the measurement of the Michel ρ parameter is expected to be a factor of three lower than the present reported value. The detectors are operational, and data taking has begun

  3. High sensitivity tests of the standard model for electroweak interactions

    International Nuclear Information System (INIS)

    Koetke, D.D.; Manweiler, R.W.; Shirvel Stanislaus, T.D.

    1993-01-01

    The work done on this project was focused on two LAMPF experiments. The MEGA experiment, a high-sensitivity search for the lepton-family-number-violating decay μ → e γ to a sensitivity which, measured in terms of the branching ratio, BR = [μ → e γ]/[μ → ev μ v e ] ∼ 10 -13 , is over two orders of magnitude better than previously reported values. The second is a precision measurement of the Michel ρ parameter from the positron energy spectrum of μ → ev μ v e to test the V-A theory of weak interactions. The uncertainty in the measurement of the Michel ρ parameter is expected to be a factor of three lower than the present reported value

  4. Highly Sensitive Filter Paper Substrate for SERS Trace Explosives Detection

    Directory of Open Access Journals (Sweden)

    Pedro M. Fierro-Mercado

    2012-01-01

    Full Text Available We report on a novel and extremely low-cost surface-enhanced Raman spectroscopy (SERS substrate fabricated depositing gold nanoparticles on common lab filter paper using thermal inkjet technology. The paper-based substrate combines all advantages of other plasmonic structures fabricated by more elaborate techniques with the dynamic flexibility given by the inherent nature of the paper for an efficient sample collection, robustness, and stability. We describe the fabrication, characterization, and SERS activity of our substrate using 2,4,6-trinitrotoluene, 2,4-dinitrotoluene, and 1,3,5-trinitrobenzene as analytes. The paper-based SERS substrates presented a high sensitivity and excellent reproducibility for analytes employed, demonstrating a direct application in forensic science and homeland security.

  5. BH3105 type neutron dose equivalent meter of high sensitivity

    International Nuclear Information System (INIS)

    Ji Changsong; Zhang Enshan; Yang Jianfeng; Zhang Hong; Huang Jiling

    1995-10-01

    It is noted that to design a neutron dose meter of high sensitivity is almost impossible in the frame of traditional designing principle--'absorption net principle'. Based on a newly proposed principle of obtaining neutron dose equi-biological effect adjustment--' absorption stick principle', a brand-new neutron dose-equivalent meter with high neutron sensitivity BH3105 has been developed. Its sensitivity reaches 10 cps/(μSv·h -1 ), which is 18∼40 times higher than one of foreign products of the same kind and is 10 4 times higher than that of domestic FJ342 neutron rem-meter. BH3105 has a measurement range from 0.1μSv/h to 1 Sv/h which is 1 or 2 orders wider than that of the other's. It has the advanced properties of gamma-resistance, energy response, orientation, etc. (6 tabs., 5 figs.)

  6. High sensitive quench detection method using an integrated test wire

    International Nuclear Information System (INIS)

    Fevrier, A.; Tavergnier, J.P.; Nithart, H.; Kiblaire, M.; Duchateau, J.L.

    1981-01-01

    A high sensitive quench detection method which works even in the presence of an external perturbing magnetic field is reported. The quench signal is obtained from the difference in voltages at the superconducting winding terminals and at the terminals at a secondary winding strongly coupled to the primary. The secondary winding could consist of a ''zero-current strand'' of the superconducting cable not connected to one of the winding terminals or an integrated normal test wire inside the superconducting cable. Experimental results on quench detection obtained by this method are described. It is shown that the integrated test wire method leads to efficient and sensitive quench detection, especially in the presence of an external perturbing magnetic field

  7. Highly sensitive high resolution Raman spectroscopy using resonant ionization methods

    International Nuclear Information System (INIS)

    Owyoung, A.; Esherick, P.

    1984-05-01

    In recent years, the introduction of stimulated Raman methods has offered orders of magnitude improvement in spectral resolving power for gas phase Raman studies. Nevertheless, the inherent weakness of the Raman process suggests the need for significantly more sensitive techniques in Raman spectroscopy. In this we describe a new approach to this problem. Our new technique, which we call ionization-detected stimulated Raman spectroscopy (IDSRS), combines high-resolution SRS with highly-sensitive resonant laser ionization to achieve an increase in sensitivity of over three orders of magnitude. The excitation/detection process involves three sequential steps: (1) population of a vibrationally excited state via stimulated Raman pumping; (2) selective ionization of the vibrationally excited molecule with a tunable uv source; and (3) collection of the ionized species at biased electrodes where they are detected as current in an external circuit

  8. A simple, tunable, and highly sensitive radio-frequency sensor.

    Science.gov (United States)

    Cui, Yan; Sun, Jiwei; He, Yuxi; Wang, Zheng; Wang, Pingshan

    2013-08-05

    We report a radio frequency (RF) sensor that exploits tunable attenuators and phase shifters to achieve high-sensitivity and broad band frequency tunability. Three frequency bands are combined to enable sensor operations from ∼20 MHz to ∼38 GHz. The effective quality factor ( Q eff ) of the sensor is as high as ∼3.8 × 10 6 with 200  μ l of water samples. We also demonstrate the measurement of 2-proponal-water-solution permittivity at 0.01 mole concentration level from ∼1 GHz to ∼10 GHz. Methanol-water solution and de-ionized water are used to calibrate the RF sensor for the quantitative measurements.

  9. Development of miniature γ dose rate monitor with high sensitivity

    International Nuclear Information System (INIS)

    Shi Huilu; Tuo Xianguo; Xi Dashun; Tang Rong; Mu Keliang; Yang Jianbo

    2009-01-01

    This paper introduces a miniature γ dose rate monitor with high sensitivity which design based on single chip microcomputer, it can continue monitoring γ dose rate and then choose wire or wireless communications to sent the monitoring data to host according to the actual conditions. It has two kinds of power supply system, AC power supply system and battery which can be chose by concrete circumstances. The design idea and implementation technology of hardware and software and the system structure of the monitor are detailed illustrated in this paper. The experimental results show that measurable range is 0.1 mR/h-200 mR/h, the sensitivity of γ is 90 cps/mR/h, dead time below 200 us, error of stability below ±10%. (authors)

  10. Wide bandwidth transimpedance amplifier for extremely high sensitivity continuous measurements.

    Science.gov (United States)

    Ferrari, Giorgio; Sampietro, Marco

    2007-09-01

    This article presents a wide bandwidth transimpedance amplifier based on the series of an integrator and a differentiator stage, having an additional feedback loop to discharge the standing current from the device under test (DUT) to ensure an unlimited measuring time opportunity when compared to switched discharge configurations while maintaining a large signal amplification over the full bandwidth. The amplifier shows a flat response from 0.6 Hz to 1.4 MHz, the capability to operate with leakage currents from the DUT as high as tens of nanoamperes, and rail-to-rail dynamic range for sinusoidal current signals independent of the DUT leakage current. Also available is a monitor output of the stationary current to track experimental slow drifts. The circuit is ideal for noise spectral and impedance measurements of nanodevices and biomolecules when in the presence of a physiological medium and in all cases where high sensitivity current measurements are requested such as in scanning probe microscopy systems.

  11. Development of High Sensitivity Nuclear Emulsion and Fine Grained Emulsion

    Science.gov (United States)

    Kawahara, H.; Asada, T.; Naka, T.; Naganawa, N.; Kuwabara, K.; Nakamura, M.

    2014-08-01

    Nuclear emulsion is a particle detector having high spacial resolution and angular resolution. It became useful for large statistics experiment thanks to the development of automatic scanning system. In 2010, a facility for emulsion production was introduced and R&D of nuclear emulsion began at Nagoya university. In this paper, we present results of development of the high sensitivity emulsion and fine grained emulsion for dark matter search experiment. Improvement of sensitivity is achieved by raising density of silver halide crystals and doping well-adjusted amount of chemicals. Production of fine grained emulsion was difficult because of unexpected crystal condensation. By mixing polyvinyl alcohol (PVA) to gelatin as a binder, we succeeded in making a stable fine grained emulsion.

  12. Development of High Sensitivity Nuclear Emulsion and Fine Grained Emulsion

    International Nuclear Information System (INIS)

    Kawahara, H.; Asada, T.; Naka, T.; Naganawa, N.; Kuwabara, K.; Nakamura, M.

    2014-01-01

    Nuclear emulsion is a particle detector having high spacial resolution and angular resolution. It became useful for large statistics experiment thanks to the development of automatic scanning system. In 2010, a facility for emulsion production was introduced and R and D of nuclear emulsion began at Nagoya university. In this paper, we present results of development of the high sensitivity emulsion and fine grained emulsion for dark matter search experiment. Improvement of sensitivity is achieved by raising density of silver halide crystals and doping well-adjusted amount of chemicals. Production of fine grained emulsion was difficult because of unexpected crystal condensation. By mixing polyvinyl alcohol (PVA) to gelatin as a binder, we succeeded in making a stable fine grained emulsion

  13. A high sensitivity nanomaterial based SAW humidity sensor

    Energy Technology Data Exchange (ETDEWEB)

    Wu, T-T; Chou, T-H [Institute of Applied Mechanics, National Taiwan University, Taipei 106, Taiwan (China); Chen, Y-Y [Department of Mechanical Engineering, Tatung University, Taipei 104, Taiwan (China)], E-mail: wutt@ndt.iam.ntu.edu.tw

    2008-04-21

    In this paper, a highly sensitive humidity sensor is reported. The humidity sensor is configured by a 128{sup 0}YX-LiNbO{sub 3} based surface acoustic wave (SAW) resonator whose operating frequency is at 145 MHz. A dual delay line configuration is realized to eliminate external temperature fluctuations. Moreover, for nanostructured materials possessing high surface-to-volume ratio, large penetration depth and fast charge diffusion rate, camphor sulfonic acid doped polyaniline (PANI) nanofibres are synthesized by the interfacial polymerization method and further deposited on the SAW resonator as selective coating to enhance sensitivity. The humidity sensor is used to measure various relative humidities in the range 5-90% at room temperature. Results show that the PANI nanofibre based SAW humidity sensor exhibits excellent sensitivity and short-term repeatability.

  14. High-Sensitivity GaN Microchemical Sensors

    Science.gov (United States)

    Son, Kyung-ah; Yang, Baohua; Liao, Anna; Moon, Jeongsun; Prokopuk, Nicholas

    2009-01-01

    Systematic studies have been performed on the sensitivity of GaN HEMT (high electron mobility transistor) sensors using various gate electrode designs and operational parameters. The results here show that a higher sensitivity can be achieved with a larger W/L ratio (W = gate width, L = gate length) at a given D (D = source-drain distance), and multi-finger gate electrodes offer a higher sensitivity than a one-finger gate electrode. In terms of operating conditions, sensor sensitivity is strongly dependent on transconductance of the sensor. The highest sensitivity can be achieved at the gate voltage where the slope of the transconductance curve is the largest. This work provides critical information about how the gate electrode of a GaN HEMT, which has been identified as the most sensitive among GaN microsensors, needs to be designed, and what operation parameters should be used for high sensitivity detection.

  15. Effective dose calculation in CT using high sensitivity TLDs

    International Nuclear Information System (INIS)

    Brady, Z.; Johnston, P.N.

    2010-01-01

    Full text: To determine the effective dose for common paediatric CT examinations using thermoluminescence dosimetry (TLD) mea surements. High sensitivity TLD chips (LiF:Mg,Cu,P, TLD-IOOH, Thermo Fisher Scientific, Waltham, MA) were calibrated on a linac at an energy of 6 MY. A calibration was also performed on a superricial X-ray unit at a kilovoltage energy to validate the megavoltage cali bration for the purpose of measuring doses in the diagnostic energy range. The dose variation across large organs was assessed and a methodology for TLD placement in a 10 year old anthropomorphic phantom developed. Effective dose was calculated from the TLD measured absorbed doses for typical CT examinations after correcting for the TLD energy response and taking into account differences in the mass energy absorption coefficients for different tissues and organs. Results Using new tissue weighting factors recommended in ICRP Publication 103, the effective dose for a CT brain examination on a 10 year old was 1.6 millisieverts (mSv), 4.9 mSv for a CT chest exa ination and 4.7 mSv for a CT abdomen/pelvis examination. These values are lower for the CT brain examination, higher for the CT chest examination and approximately the same for the CT abdomen/ pelvis examination when compared with effective doses calculated using ICRP Publication 60 tissue weighting factors. Conclusions High sensitivity TLDs calibrated with a radiotherapy linac are useful for measuring dose in the diagnostic energy range and overcome limitations of output reproducibility and uniformity asso ciated with traditional TLD calibration on CT scanners or beam quality matched diagnostic X-ray units.

  16. Phase sensitive diffraction sensor for high sensitivity refractive index measurement

    Science.gov (United States)

    Kumawat, Nityanand; Varma, Manoj; Kumar, Sunil

    2018-02-01

    In this study a diffraction based sensor has been developed for bio molecular sensing applications and performing assays in real time. A diffraction grating fabricated on a glass substrate produced diffraction patterns both in transmission and reflection when illuminated by a laser diode. We used zeroth order I(0,0) as reference and first order I(0,1) as signal channel and conducted ratiometric measurements that reduced noise by more than 50 times. The ratiometric approach resulted in a very simple instrumentation with very high sensitivity. In the past, we have shown refractive index measurements both for bulk and surface adsorption using the diffractive self-referencing approach. In the current work we extend the same concept to higher diffraction orders. We have considered order I(0,1) and I(1,1) and performed ratiometric measurements I(0,1)/I(1,1) to eliminate the common mode fluctuations. Since orders I(0,1) and I(1,1) behaved opposite to each other, the resulting ratio signal amplitude increased more than twice compared to our previous results. As a proof of concept we used different salt concentrations in DI water. Increased signal amplitude and improved fluid injection system resulted in more than 4 times improvement in detection limit, giving limit of detection 1.3×10-7 refractive index unit (RIU) compared to our previous results. The improved refractive index sensitivity will help significantly for high sensitivity label free bio sensing application in a very cost-effective and simple experimental set-up.

  17. Highly sensitive detection using microring resonator and nanopores

    Science.gov (United States)

    Bougot-Robin, K.; Hoste, J. W.; Le Thomas, N.; Bienstman, P.; Edel, J. B.

    2016-04-01

    One of the most significant challenges facing physical and biological scientists is the accurate detection and identification of single molecules in free-solution environments. The ability to perform such sensitive and selective measurements opens new avenues for a large number of applications in biological, medical and chemical analysis, where small sample volumes and low analyte concentrations are the norm. Access to information at the single or few molecules scale is rendered possible by a fine combination of recent advances in technologies. We propose a novel detection method that combines highly sensitive label-free resonant sensing obtained with high-Q microcavities and position control in nanoscale pores (nanopores). In addition to be label-free and highly sensitive, our technique is immobilization free and does not rely on surface biochemistry to bind probes on a chip. This is a significant advantage, both in term of biology uncertainties and fewer biological preparation steps. Through combination of high-Q photonic structures with translocation through nanopore at the end of a pipette, or through a solid-state membrane, we believe significant advances can be achieved in the field of biosensing. Silicon microrings are highly advantageous in term of sensitivity, multiplexing, and microfabrication and are chosen for this study. In term of nanopores, we both consider nanopore at the end of a nanopipette, with the pore being approach from the pipette with nanoprecise mechanical control. Alternatively, solid state nanopores can be fabricated through a membrane, supporting the ring. Both configuration are discussed in this paper, in term of implementation and sensitivity.

  18. Field test investigation of high sensitivity fiber optic seismic geophone

    Science.gov (United States)

    Wang, Meng; Min, Li; Zhang, Xiaolei; Zhang, Faxiang; Sun, Zhihui; Li, Shujuan; Wang, Chang; Zhao, Zhong; Hao, Guanghu

    2017-10-01

    Seismic reflection, whose measured signal is the artificial seismic waves ,is the most effective method and widely used in the geophysical prospecting. And this method can be used for exploration of oil, gas and coal. When a seismic wave travelling through the Earth encounters an interface between two materials with different acoustic impedances, some of the wave energy will reflect off the interface and some will refract through the interface. At its most basic, the seismic reflection technique consists of generating seismic waves and measuring the time taken for the waves to travel from the source, reflect off an interface and be detected by an array of geophones at the surface. Compared to traditional geophones such as electric, magnetic, mechanical and gas geophone, optical fiber geophones have many advantages. Optical fiber geophones can achieve sensing and signal transmission simultaneously. With the development of fiber grating sensor technology, fiber bragg grating (FBG) is being applied in seismic exploration and draws more and more attention to its advantage of anti-electromagnetic interference, high sensitivity and insensitivity to meteorological conditions. In this paper, we designed a high sensitivity geophone and tested its sensitivity, based on the theory of FBG sensing. The frequency response range is from 10 Hz to 100 Hz and the acceleration of the fiber optic seismic geophone is over 1000pm/g. sixteen-element fiber optic seismic geophone array system is presented and the field test is performed in Shengli oilfield of China. The field test shows that: (1) the fiber optic seismic geophone has a higher sensitivity than the traditional geophone between 1-100 Hz;(2) The low frequency reflection wave continuity of fiber Bragg grating geophone is better.

  19. A CMOS In-Pixel CTIA High Sensitivity Fluorescence Imager.

    Science.gov (United States)

    Murari, Kartikeya; Etienne-Cummings, Ralph; Thakor, Nitish; Cauwenberghs, Gert

    2011-10-01

    Traditionally, charge coupled device (CCD) based image sensors have held sway over the field of biomedical imaging. Complementary metal oxide semiconductor (CMOS) based imagers so far lack sensitivity leading to poor low-light imaging. Certain applications including our work on animal-mountable systems for imaging in awake and unrestrained rodents require the high sensitivity and image quality of CCDs and the low power consumption, flexibility and compactness of CMOS imagers. We present a 132×124 high sensitivity imager array with a 20.1 μm pixel pitch fabricated in a standard 0.5 μ CMOS process. The chip incorporates n-well/p-sub photodiodes, capacitive transimpedance amplifier (CTIA) based in-pixel amplification, pixel scanners and delta differencing circuits. The 5-transistor all-nMOS pixel interfaces with peripheral pMOS transistors for column-parallel CTIA. At 70 fps, the array has a minimum detectable signal of 4 nW/cm(2) at a wavelength of 450 nm while consuming 718 μA from a 3.3 V supply. Peak signal to noise ratio (SNR) was 44 dB at an incident intensity of 1 μW/cm(2). Implementing 4×4 binning allowed the frame rate to be increased to 675 fps. Alternately, sensitivity could be increased to detect about 0.8 nW/cm(2) while maintaining 70 fps. The chip was used to image single cell fluorescence at 28 fps with an average SNR of 32 dB. For comparison, a cooled CCD camera imaged the same cell at 20 fps with an average SNR of 33.2 dB under the same illumination while consuming over a watt.

  20. Sensors for the CMS High Granularity Calorimeter

    CERN Document Server

    Maier, Andreas Alexander

    2017-01-01

    The CMS experiment is currently developing high granularity calorimeter endcapsfor its HL-LHC upgrade. The design foresees silicon sensors as the active material for the high radiation region close to the beampipe. Regions of lower radiation are additionally equipped with plastic scintillator tiles. This technology is similar to the calorimeter prototypes developed in the framework of the Linear Collider by the CALICE collaboration. The current status of the silicon sensor development is presented. Results of single diode measurements are shown as well as tests of full 6-inch hexagonal sensor wafers. A short summary of test beam results concludes the article.

  1. Nonuniformities in organic liquid ionization calorimeters

    International Nuclear Information System (INIS)

    Wenzel, W.A.

    1989-06-01

    Hermeticity and uniformity in SSC calorimeter designs are compromised by structure and modularity. Some of the consequences of the cryogenic needs of liquid argon calorimetry are relatively well known. If the active medium is an organic liquid (TMP, TMS, etc.), a large number of independent liquid volumes is needed for safety and for rapid liquid exchange to eliminate local contamination. Modular construction ordinarily simplifies fabrication, assembly, handling and preliminary testing at the price of additional walls, other dead regions and many nonuniformities. Here we examine ways of minimizing the impact of some generic nonuniformities on the quality of calorimeter performance. 6 refs., 7 figs

  2. Rad Hard Active Media For Calorimeters

    CERN Document Server

    Norbeck, E; Möller, A; Onel, Y

    2006-01-01

    Zero-degree calorimeters have limited space and extreme levels of radiation. A simple, low cost, radiation hard design uses tungstenmetal as the absorber and a suitable liquid as the ˇCerenkov radiator. In other applications a PPAC (Parallel Plate Avalanche Counter) operatingwith a suitable atmosphericpressure gas is an attractive active material for a calorimeter. It can be made radiation hard and has sufficient gain in the gas that no electronic components are needed near the detector. It works well even with the highest concentration of shower particles. For this pressure range, R134A (used in auto air conditioners) has many desirable features.

  3. Fast shower simulation in the ATLAS calorimeter

    CERN Document Server

    Barberio, E; Butler, B; Cheung, S L; Dell'Acqua, A; Di Simone, A; Ehrenfeld, W; Gallas, M V; Glazov, A; Marshall, Z; Müller, J; Placakyte, R; Rimoldi, A; Savard, P; Tsulaia, V; Waugh, A; Young, C C

    2008-01-01

    The time to simulate pp collisions in the ATLAS detector is largely dominated by the showering of electromagnetic particles in the heavy parts of the detector, especially the electromagnetic barrel and endcap calorimeters. Two procedures have been developed to accelerate the processing time of electromagnetic particles in these regions: (1) a fast shower parameterisation and (2) a frozen shower library. Both work by generating the response of the calorimeter to electrons and positrons with Geant 4, and then reintroduce the response into the simulation at runtime.

  4. Commissioning of the ATLAS Liquid Argon Calorimeters

    CERN Document Server

    Cooke, M; The ATLAS collaboration

    2009-01-01

    Since the first modules of the ATLAS LAr calorimeters were read out in situ in 2006, commissioning studies have been performed. These studies include the testing of the electronics calibration system, surveys for dead or problematic channels, investigations of the quality of the physics pulse shape prediction , and tests of energy and time reconstruction with cosmic or single beam induced signals. The results of these commissioning studies indicate the LAr calorimeters are prepared for LHC collisions and positioned to meet the physics objectives of the ATLAS experiment.

  5. Radiation damage effects on calorimeter compensation

    International Nuclear Information System (INIS)

    Gabriel, T.A.; Handler, T.

    1990-01-01

    An important consideration in the design of a detector that is to be used at the Superconducting Super Collider (SSC) is the response of the calorimeter to electromagnetic and hadronic particles and the equality of those responses for different types of particles at equal incident energies, i.e. compensation. However, as the simulations that are reported show, the compensation characteristics of a calorimeter can be seriously compromised over a relatively short period of time due to the large radiation levels that are expected in the SSC environment. 6 refs., 3 figs

  6. Comparison between calorimeter and HLNC errors

    International Nuclear Information System (INIS)

    Goldman, A.S.; De Ridder, P.; Laszlo, G.

    1991-01-01

    This paper summarizes an error analysis that compares systematic and random errors of total plutonium mass estimated for high-level neutron coincidence counter (HLNC) and calorimeter measurements. This task was part of an International Atomic Energy Agency (IAEA) study on the comparison of the two instruments to determine if HLNC measurement errors met IAEA standards and if the calorimeter gave ''significantly'' better precision. Our analysis was based on propagation of error models that contained all known sources of errors including uncertainties associated with plutonium isotopic measurements. 5 refs., 2 tabs

  7. Comparison of the Heat Release Rate from the Mass Loss Calorimeter to the Cone Calorimeter for Wood-based Materials

    Science.gov (United States)

    Laura E. Hasburgh; Robert H. White; Mark A. Dietenberger; Charles R. Boardman

    2015-01-01

    There is a growing demand for material properties to be used as inputs in fi re behavior models designed to address building fire safety. This comparative study evaluates using the mass loss calorimeter as an alternative to the cone calorimeter for obtaining heat release rates of wood-based materials. For this study, a modified mass loss calorimeter utilized an...

  8. Microfluidic fuel cells and batteries

    CERN Document Server

    Kjeang, Erik

    2014-01-01

    Microfluidic fuel cells and batteries represent a special type of electrochemical power generators that can be miniaturized and integrated in a microfluidic chip. Summarizing the initial ten years of research and development in this emerging field, this SpringerBrief is the first book dedicated to microfluidic fuel cell and battery technology for electrochemical energy conversion and storage. Written at a critical juncture, where strategically applied research is urgently required to seize impending technology opportunities for commercial, analytical, and educational utility, the intention is

  9. Study of a novel electromagnetic liquid argon calorimeter - the TGT

    Energy Technology Data Exchange (ETDEWEB)

    Berger, C. [Technische Hochschule Aachen (Germany). 1. Physikalisches Inst.; Braunschweig, W. [Technische Hochschule Aachen (Germany). 1. Physikalisches Inst.; Geulig, E. [Technische Hochschule Aachen (Germany). 1. Physikalisches Inst.; Schoentag, M. [Technische Hochschule Aachen (Germany). 1. Physikalisches Inst.; Siedling, R. [Technische Hochschule Aachen (Germany). 1. Physikalisches Inst.; Wlochal, M. [Technische Hochschule Aachen (Germany). 1. Physikalisches Inst.; Putzer, A. [European Organization for Nuclear Research, Geneva (Switzerland); Wotschack, J. [European Organization for Nuclear Research, Geneva (Switzerland); Cheplakov, A. [Joint Inst. for Nuclear Research, Dubna (Russian Federation); Feshchenko, A. [Joint Inst. for Nuclear Research, Dubna (Russian Federation); Kazarinov, M. [Joint Inst. for Nuclear Research, Dubna (Russian Federation); Kukhtin, V. [Joint Inst. for Nuclear Research, Dubna (Russian Federation); Ladygin, E. [Joint Inst. for Nuclear Research, Dubna (Russian Federation); Obudovskij, V. [Joint Inst. for Nuclear Research, Dubna (Russian Federation); Geweniger, C. [Heidelberg Univ. (Germany). Inst. fuer Hochenergiephysik; Hanke, P. [Heidelberg Univ. (Germany). Inst. fuer Hochenergiephysik; Kluge, E.E. [Heidelberg Univ. (Germany). Inst. fuer Hochenergiephysik; Krause, J. [Heidelberg Univ. (Germany). Inst. fuer Hochenergiephysik; Schmidt, M. [Heidelberg Univ. (Germany). Inst. fuer Hochenergiephysik; Stenzel, H. [Heidelberg Univ. (Germany). Inst. fuer Hochenergiephysik; Tittel, K. [Heidelberg Univ. (Germany). Inst. fuer Hochenergiephysik; Wunsch, M. [Heidelberg Univ. (Germany). Inst. fuer Hochenergiephysik; Zerwas, D. [Heidelberg Univ. (Germany). Inst. fuer Hochenergiephysik; Bruncko, D. [Slovenska Akademia Vied, Kosice (Slovakia). Ustav Experimentalnej Fyziky; Jusko, A. [Slovenska Akademia Vied, Kosice (Slovakia). Ustav Experimentalnej Fyziky; Kocper, B.; RD33 Collaboration

    1994-11-01

    The concept and the basic design of a fast, highly granular and compact electromagnetic liquid argon calorimeter are described. This novel calorimeter offers uniform energy response and constant energy resolution independent of the production angle of an impinging particle and of its impact position at the calorimeter. An example of a calorimeter with full rapidity coverage in an application in a collider detector is given. An important aspect of the concept is the electronics for fast signal processing matched to the short charge collection time. We report on the experience with the realization of a prototype calorimeter module and on its performance in a testbeam exposure. (orig.)

  10. Study of a novel electromagnetic liquid argon calorimeter TGT

    International Nuclear Information System (INIS)

    Berger, C.; Braunschweig, W.; Geulig, E.

    1994-01-01

    The concept and the basic design of a fast, highly granular and compact electromagnetic liquid argon calorimeter are described. This novel calorimeter offers uniform energy response and constant energy resolution independent of the production angle of an impinging particle and of its impact position at the calorimeter. An example of a calorimeter with full rapidity coverage in an application in a collider detector is given. An important aspect of the concept is the electronics for fast signal processing matched to the short charge collection time. We report on the experience with the realization of a prototype calorimeter module and on its performance in a test beam exposure. 15 refs., 16 figs., 2 tabs

  11. Study of a novel electromagnetic liquid argon calorimeter - the TGT

    Energy Technology Data Exchange (ETDEWEB)

    Berger, C.; Braunschweig, W.; Geulig, E. [Technische Hochschule Aachen (Germany). 1. Physikalisches Inst.] [and others

    1995-04-21

    The concept and the basic design of a fast, highly granular and compact electromagnetic liquid argon calorimeter are described. This novel calorimeter offers uniform energy response and constant energy resolution independent of the production angle of an impinging particle and of its impact position at the calorimeter. An example of a calorimeter with full rapidity coverage in an application in a collider detector is given. An important aspect of the concept is the electronics for fast signal processing matched to the short charge collection time. We report on the experience with the realization of a prototype calorimeter module and on its performance in a testbeam exposure. ((orig.)).

  12. Study of a novel electromagnetic liquid argon calorimeter - the TGT

    International Nuclear Information System (INIS)

    Berger, C.; Braunschweig, W.; Geulig, E.

    1995-01-01

    The concept and the basic design of a fast, highly granular and compact electromagnetic liquid argon calorimeter are described. This novel calorimeter offers uniform energy response and constant energy resolution independent of the production angle of an impinging particle and of its impact position at the calorimeter. An example of a calorimeter with full rapidity coverage in an application in a collider detector is given. An important aspect of the concept is the electronics for fast signal processing matched to the short charge collection time. We report on the experience with the realization of a prototype calorimeter module and on its performance in a testbeam exposure. ((orig.))

  13. Monte Carlo simulation of a gas-sampled hadron calorimeter

    Energy Technology Data Exchange (ETDEWEB)

    Chang, C Y; Kunori, S; Rapp, P; Talaga, R; Steinberg, P; Tylka, A J; Wang, Z M

    1988-02-15

    A prototype of the OPAL barrel hadron calorimeter, which is a gas-sampled calorimeter using plastic streamer tubes, was exposed to pions at energies between 1 and 7 GeV. The response of the detector was simulated using the CERN GEANT3 Monte Carlo program. By using the observed high energy muon signals to deduce details of the streamer formation, the Monte Carlo program was able to reproduce the observed calorimeter response. The behavior of the hadron calorimeter when placed behind a lead glass electromagnetic calorimeter was also investigated.

  14. CsI calorimeter of the CMD-3 detector

    International Nuclear Information System (INIS)

    Aulchenko, V.M.; Bondar, A.E.; Erofeev, A.L.; Kovalenko, O.A.; Kozyrev, A.N.; Kuzmin, A.S.; Logashenko, I.B.; Razuvaev, G.P.; Ruban, A.A.; Shebalin, V.E.; Shwartz, B.A.; Talyshev, A.A.; Titov, V.M.; Yudin, Yu.V.; Epifanov, D.A.

    2015-01-01

    The VEPP-2000 e + e − collider has been operated at Budker Institute of Nuclear Physics since 2010. The experiments are performed with two detectors CMD-3 and SND. The calorimetry at the CMD-3 detector is based on three subsystems, two coaxial barrel calorimeters—Liquid Xenon Calorimeter and crystal CsI calorimeter, and endcap calorimeter with BGO crystals. This paper describes the CsI calorimeter of the CMD-3 detector. The calorimeter design, its electronics and calibration procedures are discussed

  15. The ATLAS Tile Calorimeter gets into shape!

    CERN Multimedia

    2002-01-01

    The last of the 64 modules for one of the ATLAS Hadron tile calorimeter barrels has just arrived at CERN. This arrival puts an end to two and a half years work assembling and testing all the modules in the Institut de Física d'Altes Energies (IFAE), in Barcelona.

  16. Upgrading the ATLAS Tile Calorimeter Electronics

    CERN Document Server

    Oreglia, M; The ATLAS collaboration

    2013-01-01

    The ATLAS detector hadron calorimeter electronics are being redesigned to address issues associated with the High Luminosity mode of LHC running in Phase-2. We describe the issues and solutions and also discuss a demonstrator unit to be installed on the detector in 2014.

  17. ATLAS: First rehearsal for the tile calorimeter

    CERN Multimedia

    2003-01-01

    The dry run assembly of the first barrel of the ATLAS tile hadron calorimeter has been successfully completed. It is now being dismantled again so that it can be lowered into the ATLAS cavern where it will be reassembled in October 2004.

  18. Pion showers in highly granular calorimeters

    Indian Academy of Sciences (India)

    New results on properties of hadron showers created by pion beam at 8–80 GeV in high granular electromagnetic and hadron calorimeters are presented. Data were used for the first time to investigate the separation of the neutral and charged hadron showers. The result is important to verify the prediction of the PFA ...

  19. Evolution of the dual-readout calorimeter

    Indian Academy of Sciences (India)

    ... a calorimeter system of a relatively simple construction and moderate costs, however with excellent properties, built upon experience gained with the extensively beam-tested DREAM (Dual REAdout. Module) prototype. The main idea of multiple readout calorimetry is to indepen- dently measure for each hadronic shower ...

  20. Performance of a uranium liquid argon calorimeter

    International Nuclear Information System (INIS)

    Tuts, P.M.

    1987-01-01

    The author presents results on the performance of a uranium and liquid argon colorimeter in the NW test beam at Fermilab. This study describes the calorimeter, and discusses its performance with electrons, pions and muons from 10 GeV to 150 GeV. The performance parameters measure response, linearity, resolution, compensation, and e/π separation

  1. SLD liquid argon calorimeter prototype test results

    International Nuclear Information System (INIS)

    Dubois, R.; Eigen, G.; Au, Y.

    1985-10-01

    The results of the SLD test beam program for the selection of a calorimeter radiator composition within a liquid argon system are described, with emphasis on the study of the use of uranium to obtain equalization of pion and electron responses

  2. Homogeneous scintillating LKr/Xe calorimeters

    International Nuclear Information System (INIS)

    Chen, M.; Mullins, M.; Pelly, D.; Shotkin, S.; Sumorok, K.; Akyuz, D.; Chen, E.; Gaudreau, M.P.J.; Bolozdynya, A.; Tchernyshev, V.; Goritchev, P.; Khovansky, V.; Koutchenkov, A.; Kovalenko, A.; Lebedenko, V.; Vinogradov, V.; Gusev, L.; Sheinkman, V.; Krasnokutsky, R.N.; Shuvalov, R.S.; Fedyakin, N.N.; Sushkov, V.; Akopyan, M.; Doke, T.; Kikuchi, J.; Hitachi, A.; Kashiwagi, T.; Masuda, K.; Shibamura, E.; Ishida, N.; Sugimoto, S.

    1993-01-01

    Recent R and D work on full length scintillating homogeneous liquid xenon/krypton (LXe/Kr) cells has established the essential properties for precision EM calorimeters: In-situ calibration using α's, radiation hardness as well as the uniformity required for δE/E≅0.5% for e/γ's above 50 GeV. (orig.)

  3. Commissioning of the ATLAS Liquid Argon Calorimeters

    CERN Document Server

    Cooke, Mark S

    2009-01-01

    A selection of ATLAS liquid argon (LAr) calorimeter commissioning studies are presented. These include a coherent noise study, a measurement of the quality of the physics pulse shape prediction, and energy and time reconstruction analyses with cosmic and single beam signals.

  4. PEP-4 geiger-mode hexagonal calorimeter

    International Nuclear Information System (INIS)

    Wenzel, W.A.

    1982-01-01

    The design and performance of the calorimeter are briefly described. Design aspects include illustrations of the active volume of the detector, edge connections, module assembly and analog electronics. Performance data for cosmic rays and radiation sources, including efficiency and channel sensitivity are discussed

  5. Calibration of the ZEUS forward calorimeter

    International Nuclear Information System (INIS)

    Kraemer, M.

    1990-10-01

    The physics at the ep-collider HERA requires high resolution calorimetry calibrated with an accuracy of better than 2%. The ZEUS detector meets these conditions by means of a compensating uranium scintillator sandwich calorimeter with an energy resolution of σ/E = 35%/√E + σ cal , where σ cal is the calibration error. One of the tools to minimize σ cal is the calibration with the signals of the radioactivity of the Uranium plates (UNO). Taking UNO data every 8 hours keeps the calibration stable within ≅ 1%. The muon calibration is done employing an algorithm, that determines the most probable energy loss with a precision of ≅ 1%. The channel-to-channel fluctuations of the ratio μ/UNO for a forward calorimeter (FCAL) prototype show a spread of 5.2% for the electromagnetic calorimeter and ≅ 2.5% for the hadronic sections. Improvements in the construction of the FCAL modules decreased these fluctuations to 2.0% and ≅ 1.8% respectively. The influence of the cracks between the calorimeter modules amounts to ≅ 1.7% on average for the ZEUS geometry, if a 2 mm thick Pb-sheet is introduced between the modules. We conclude that we are able to keep σ cal below 2%. (orig.)

  6. The new ATLAS Fast Calorimeter Simulation

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00223142; The ATLAS collaboration

    2016-01-01

    Many physics and performance studies with the ATLAS detector at the Large Hadron Collider require very large samples of simulated events, and producing these using the full GEANT4 detector simulation is highly CPU intensive. Often, a very detailed detector simulation is not needed, and in these cases fast simulation tools can be used to reduce the calorimeter simulation time by a few orders of magnitude. The new ATLAS Fast Calorimeter Simulation (FastCaloSim) is an improved parametrisation compared to the one used in the LHC Run-1. It provides a simulation of the particle energy response at the calorimeter read-out cell level, taking into account the detailed particle shower shapes and the correlations between the energy depositions in the various calorimeter layers. It is interfaced to the standard ATLAS digitization and reconstruction software, and can be tuned to data more easily than with GEANT4. The new FastCaloSim incorporates developments in geometry and physics lists of the last five years and benefit...

  7. The new ATLAS Fast Calorimeter Simulation

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00176100; The ATLAS collaboration

    2016-01-01

    The physics and performance studies of the ATLAS detector at the Large Hadron Collider re- quire a large number of simulated events. A GEANT4 based detailed simulation of the ATLAS calorimeter systems is highly CPU intensive and such resolution is often unnecessary. To reduce the calorimeter simulation time by a few orders of magnitude, fast simulation tools have been developed. The Fast Calorimeter Simulation (FastCaloSim) provides a parameterised simulation of the particle energy response at the calorimeter read-out cell level. In Run 1, about 13 billion events were simulated in ATLAS, out of which 50% were produced using fast simulation. For Run 2, a new parameterisation is being developed to improve the original version: it incorporates developments in geometry and physics lists during the last five years and benefits from the knowledge acquired from the Run 1 data. The algorithm uses machine learning techniques to improve the parameterisations and to optimise the amount of information to be stored in the...

  8. CALICE silicon-tungsten electromagnetic calorimeter

    Indian Academy of Sciences (India)

    A highly granular electromagnetic calorimeter prototype based on tungsten absorber and sampling units equipped with silicon pads as sensitive devices for signal collection is under construction. The full prototype will have in total 30 layers and be read out by about 10000 Si cells of 1 × 1 cm2. A first module consisting of 14 ...

  9. The BaBar electromagnetic calorimeter

    CERN Document Server

    Lewandowski, B

    2002-01-01

    The BaBar electromagnetic calorimeter is a hermetic, total-absorption array of CsI(Tl)-crystals, operated at the asymmetric e sup - e sup + -collider PEP-II at SLAC. The design and the status of the performance as of February 2002 is presented.

  10. The electromagnetic calorimeter of the CMS experiment

    International Nuclear Information System (INIS)

    Diemoza, M.

    2003-01-01

    The Electromagnetic Calorimeter of the CMS experiment is made of about 80000 Lead Tungstate scintillating crystals. This project aims to achieve an extreme precision in photons and electrons energy measurement. General motivations, main technical challenges and key points in energy resolution will be discussed in the following

  11. Performance of the ATLAS hadronic Tile calorimeter

    CERN Document Server

    Mlynarikova, Michaela; The ATLAS collaboration

    2017-01-01

    The ATLAS Tile Calorimeter (TileCal) of the ATLAS experiment at the LHC is the central hadronic calorimeter designed for reconstruction of hadrons, jets, tau-particles and missing transverse energy. TileCal is a scintillator-steel sampling calorimeter and it covers the region of pseudorapidity < 1.7. The scintillation light produced in the scintillator tiles is transmitted by wavelength shifting fibers to photomultiplier tubes (PMTs). The analog signals from the PMTs are amplified, shaped and digitized by sampling the signal every 25 ns. The TileCal frontend electronics reads out the signals produced by about 10000 channels measuring energies ranging from ~30 MeV to ~2 TeV. Each stage of the signal production from scintillation light to the signal reconstruction is monitored and calibrated. The performance of the calorimeter has been studied in-situ employing cosmic ray muons and a large sample of proton-proton collisions acquired during the operations of the LHC. Prompt isolated muons of high momentum fro...

  12. Performance of the ATLAS Tile Calorimeter

    CERN Document Server

    Hrynevich, Aliaksei; The ATLAS collaboration

    2017-01-01

    The Tile Calorimeter (TileCal) is the central scintillator-steel sampling hadronic calorimeter of the ATLAS experiment at the LHC. Jointly with other calorimeters it is designed for energy reconstruction of hadrons, jets, tau-particles and missing transverse energy. The scintillation light produced in the scintillator tiles is transmitted by wavelength shifting fibers to photomultiplier tubes (PMTs). The analog signals from the PMTs are amplified, shaped and digitized by sampling the signal every 25 ns. The TileCal frontend electronics reads out the signals produced by about 10000 channels measuring energies ranging from ~30 MeV to ~2 TeV. Each stage of the signal production from scintillation light to the signal reconstruction is monitored and calibrated. The performance of the calorimeter has been established with cosmic ray muons and the large sample of the proton-proton collisions. The response of high momentum isolated muons is used to study the energy response at the electromagnetic scale, isolated hadr...

  13. Performance of the ATLAS hadronic Tile calorimeter

    CERN Document Server

    Mlynarikova, Michaela; The ATLAS collaboration

    2017-01-01

    The Tile Calorimeter (TileCal) of the ATLAS experiment at the LHC is the central hadronic calorimeter designed for reconstruction of hadrons, jets, tau-particles and missing transverse energy. TileCal is a scintillator-steel sampling calorimeter and it covers the region of pseudorapidity < 1.7. The scintillation light produced in the scintillator tiles is transmitted by wavelength shifting fibers to photomultiplier tubes (PMTs). The analog signals from the PMTs are amplified, shaped and digitized by sampling the signal every 25 ns. The TileCal frontend electronics reads out the signals produced by about 10000 channels measuring energies ranging from ~30 MeV to ~2 TeV. Each stage of the signal production from scintillation light to the signal reconstruction is monitored and calibrated. The performance of the calorimeter has been studied in-situ employing cosmic ray muons and a large sample of proton-proton collisions acquired during the operations of the LHC. Prompt isolated muons of high momentum from elec...

  14. Upgrading the ATLAS Fast Calorimeter Simulation

    CERN Document Server

    Hubacek, Zdenek; The ATLAS collaboration

    2016-01-01

    Many physics and performance studies with the ATLAS detector at the Large Hadron Collider require very large samples of simulated events, and producing these using the full GEANT4 detector simulation is highly CPU intensive. Often, a very detailed detector simulation is not needed, and in these cases fast simulation tools can be used to reduce the calorimeter simulation time by a few orders of magnitude. In ATLAS, a fast simulation of the calorimeter systems was developed, called Fast Calorimeter Simulation (FastCaloSim). It provides a parametrized simulation of the particle energy response at the calorimeter read-out cell level. It is interfaced to the standard ATLAS digitization and reconstruction software, and can be tuned to data more easily than with GEANT4. The original version of FastCaloSim has been very important in the LHC Run-1, with several billion events simulated. An improved parametrisation is being developed, to eventually address shortcomings of the original version. It incorporates developme...

  15. The new ATLAS Fast Calorimeter Simulation

    CERN Document Server

    Dias, Flavia; The ATLAS collaboration

    2016-01-01

    A very large number of simulated events is required for physics and performance studies with the ATLAS detector at the Large Hadron Collider. Producing these with the full GEANT4 detector simulation is highly CPU intensive. As a very detailed detector simulation is not always required, fast simulation tools have been developed to reduce the calorimeter simulation time by a few orders of magnitude. The fast simulation of ATLAS for the calorimeter systems used in Run 1, called Fast Calorimeter Simulation (FastCaloSim), provides a parameterized simulation of the particle energy response at the calorimeter read-out cell level. It is then interfaced to the ATLAS digitization and reconstruction software. In Run 1, about 13 billion events were simulated in ATLAS, out of which 50% were produced using fast simulation. For Run 2, a new parameterisation is being developed to improve the original version: It incorporates developments in geometry and physics lists of the last five years and benefits from knowledge acquire...

  16. Methods of making microfluidic devices

    KAUST Repository

    Buttner, Ulrich; Mashraei, Yousof; Agambayev, Sumeyra; Salama, Khaled N.

    2017-01-01

    Microfluidics has advanced in terms of designs and structures, however, fabrication methods are either time consuming or expensive to produce, in terms of the facilities and equipment needed. A fast and economically viable method is provided

  17. Microfluidic technology for molecular diagnostics.

    Science.gov (United States)

    Robinson, Tom; Dittrich, Petra S

    2013-01-01

    Molecular diagnostics have helped to improve the lives of millions of patients worldwide by allowing clinicians to diagnose patients earlier as well as providing better ongoing therapies. Point-of-care (POC) testing can bring these laboratory-based techniques to the patient in a home setting or to remote settings in the developing world. However, despite substantial progress in the field, there still remain many challenges. Progress in molecular diagnostics has benefitted greatly from microfluidic technology. This chapter aims to summarise the more recent advances in microfluidic-based molecular diagnostics. Sections include an introduction to microfluidic technology, the challenges of molecular diagnostics, how microfluidic advances are working to solve these issues, some alternative design approaches, and detection within these systems.

  18. Rapid mask prototyping for microfluidics.

    Science.gov (United States)

    Maisonneuve, B G C; Honegger, T; Cordeiro, J; Lecarme, O; Thiry, T; Fuard, D; Berton, K; Picard, E; Zelsmann, M; Peyrade, D

    2016-03-01

    With the rise of microfluidics for the past decade, there has come an ever more pressing need for a low-cost and rapid prototyping technology, especially for research and education purposes. In this article, we report a rapid prototyping process of chromed masks for various microfluidic applications. The process takes place out of a clean room, uses a commercially available video-projector, and can be completed in less than half an hour. We quantify the ranges of fields of view and of resolutions accessible through this video-projection system and report the fabrication of critical microfluidic components (junctions, straight channels, and curved channels). To exemplify the process, three common devices are produced using this method: a droplet generation device, a gradient generation device, and a neuro-engineering oriented device. The neuro-engineering oriented device is a compartmentalized microfluidic chip, and therefore, required the production and the precise alignment of two different masks.

  19. Polypyrrole–gold nanoparticle composites for highly sensitive DNA detection

    International Nuclear Information System (INIS)

    Spain, Elaine; Keyes, Tia E.; Forster, Robert J.

    2013-01-01

    DNA capture surfaces represent a powerful approach to developing highly sensitive sensors for identifying the cause of infection. Electrochemically deposited polypyrrole, PPy, films have been functionalized with electrodeposited gold nanoparticles to give a nanocomposite material, PPy–AuNP. Thiolated capture strand DNA, that is complementary to the sequence from the pathogen Staphylococcus aureus that causes mammary gland inflammation, was then immobilized onto the gold nanoparticles and any of the underlying gold electrode that is exposed. A probe strand, labelled with horse radish peroxidase, HRP, was then hybridized to the target. The concentration of the target was determined by measuring the current generated by reducing benzoquinone produced by the HRP label. Semi-log plots of the pathogen DNA concentration vs. faradaic current are linear from 150 pM to 1 μM and pM concentrations can be detected without the need for molecular, e.g., PCR or NASBA, amplification. The nanocomposite also exhibits excellent selectivity and single base mismatches in a 30 mer sequence can be detected

  20. Operationalization of the Russian Version of Highly Sensitive Person Scale

    Directory of Open Access Journals (Sweden)

    Регина Вячеславовна Ершова

    2018-12-01

    Full Text Available The aim of the present study was to operationalize a Russian version of the Highly Sensitive Person Scale (HSPS. The empirical data were collected in two ways: active, through oral advertising and inviting those who wish to take part in the study (snowball technique and passive (placement of ads about taking part in a research in social networks VKontakte and Facebook. As a result, 350 university students (117 men, 233 women, an average age of 18,2 (± 1,7 applied to a research laboratory and filled out the HSPS questionnaire, and another 510 respondents (380 women, 130 men, average age 22,6 ( ± 7,9 filled the HSPS online. The results of the study did not confirm the one-dimensional model of the construct, proposed by Aron & Aron (1997, as well as the most commonly used in the English-language studies three-factor solution. The hierarchical claster and confirmatory analyses used in the operationalization procedure allowed us to conclude that the variance of the Russian version of HSPS is best described in the framework of a two-factor model including the two separate subscales: Ease of Excitation (EOE, Low threshold of sensitivity (LTS. Sensory Processing Sensitivity may be defined as an increased susceptibility to external and internal stimuli, realized through negative emotional responses and deep susceptibility (distress to excessive stimulation.

  1. Luminescent Lanthanide Reporters for High-Sensitivity Novel Bioassays

    Energy Technology Data Exchange (ETDEWEB)

    Anstey, Mitchell R. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Fruetel, Julia A. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Foster, Michael E. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Hayden, Carl C. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Buckley, Heather L. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Arnold, John [Sandia National Lab. (SNL-CA), Livermore, CA (United States)

    2013-09-01

    Biological imaging and assay technologies rely on fluorescent organic dyes as reporters for a number of interesting targets and processes. However, limitations of organic dyes such as small Stokes shifts, spectral overlap of emission signals with native biological fluorescence background, and photobleaching have all inhibited the development of highly sensitive assays. To overcome the limitations of organic dyes for bioassays, we propose to develop lanthanide-based luminescent dyes and demonstrate them for molecular reporting applications. This relatively new family of dyes was selected for their attractive spectral and chemical properties. Luminescence is imparted by the lanthanide atom and allows for relatively simple chemical structures that can be tailored to the application. The photophysical properties offer unique features such as narrow and non-overlapping emission bands, long luminescent lifetimes, and long wavelength emission, which enable significant sensitivity improvements over organic dyes through spectral and temporal gating of the luminescent signal.Growth in this field has been hindered due to the necessary advanced synthetic chemistry techniques and access to experts in biological assay development. Our strategy for the development of a new lanthanide-based fluorescent reporter system is based on chelation of the lanthanide metal center using absorbing chromophores. Our first strategy involves "Click" chemistry to develop 3-fold symmetric chelators and the other involves use of a new class of tetrapyrrole ligands called corroles. This two-pronged approach is geared towards the optimization of chromophores to enhance light output.

  2. Highly sensitive MoS2 photodetectors with graphene contacts

    Science.gov (United States)

    Han, Peize; St. Marie, Luke; Wang, Qing X.; Quirk, Nicholas; El Fatimy, Abdel; Ishigami, Masahiro; Barbara, Paola

    2018-05-01

    Two-dimensional materials such as graphene and transition metal dichalcogenides (TMDs) are ideal candidates to create ultra-thin electronics suitable for flexible substrates. Although optoelectronic devices based on TMDs have demonstrated remarkable performance, scalability is still a significant issue. Most devices are created using techniques that are not suitable for mass production, such as mechanical exfoliation of monolayer flakes and patterning by electron-beam lithography. Here we show that large-area MoS2 grown by chemical vapor deposition and patterned by photolithography yields highly sensitive photodetectors, with record shot-noise-limited detectivities of 8.7 × 1014 Jones in ambient condition and even higher when sealed with a protective layer. These detectivity values are higher than the highest values reported for photodetectors based on exfoliated MoS2. We study MoS2 devices with gold electrodes and graphene electrodes. The devices with graphene electrodes have a tunable band alignment and are especially attractive for scalable ultra-thin flexible optoelectronics.

  3. High-sensitivity bend angle measurements using optical fiber gratings.

    Science.gov (United States)

    Rauf, Abdul; Zhao, Jianlin; Jiang, Biqiang

    2013-07-20

    We present a high-sensitivity and more flexible bend measurement method, which is based on the coupling of core mode to the cladding modes at the bending region in concatenation with optical fiber grating serving as band reflector. The characteristics of a bend sensing arm composed of bending region and optical fiber grating is examined for different configurations including single fiber Bragg grating (FBG), chirped FBG (CFBG), and double FBGs. The bend loss curves for coated, stripped, and etched sections of fiber in the bending region with FBG, CFBG, and double FBG are obtained experimentally. The effect of separation between bending region and optical fiber grating on loss is measured. The loss responses for single FBG and CFBG configurations are compared to discover the effectiveness for practical applications. It is demonstrated that the sensitivity of the double FBG scheme is twice that of the single FBG and CFBG configurations, and hence acts as sensitivity multiplier. The bend loss response for different fiber diameters obtained through etching in 40% hydrofluoric acid, is measured in double FBG scheme that resulted in a significant increase in the sensitivity, and reduction of dead-zone.

  4. Passive microfluidic array card and reader

    Science.gov (United States)

    Dugan, Lawrence Christopher [Modesto, CA; Coleman, Matthew A [Oakland, CA

    2011-08-09

    A microfluidic array card and reader system for analyzing a sample. The microfluidic array card includes a sample loading section for loading the sample onto the microfluidic array card, a multiplicity of array windows, and a transport section or sections for transporting the sample from the sample loading section to the array windows. The microfluidic array card reader includes a housing, a receiving section for receiving the microfluidic array card, a viewing section, and a light source that directs light to the array window of the microfluidic array card and to the viewing section.

  5. Reconfigurable microfluidic platform in ice

    OpenAIRE

    Varejka, M.

    2008-01-01

    Microfluidic devices are popular tools in the biotechnology industry where they provide smaller reagent requirements, high speed of analysis and the possibility for automation. The aim of the project is to make a flexible biocompatible microfluidic platform adapted to different specific applications, mainly analytical and separations which parameters and configuration can be changed multiple times by changing corresponding computer programme. The current project has been sup...

  6. The pipelined readout for the ZEUS calorimeter

    International Nuclear Information System (INIS)

    Hervas, L.

    1991-01-01

    The electron-proton storage ring complex HERA under construction at DESY in Hamburg is the first machine of a new generation of colliders. Since physics to be studied at HERA (covered in chapter 2) base on the precise measurement of kinematic variables over a very large range of energies, a foremost emphasis is set in calorimetry. After long studies and an ambitious test program, the ZEUS collaboration has built a high resolution depleted uranium-scintillator calorimeter with photomultiplier readout, the state of the art in detectors of this type. In chapter 3 the principles of calorimetry are reviewed and the construction of the ZEUS calorimeter is described. Mainly due to the large dynamic range and the short bunch crossing times a novel concept for the readout in an analog pipelined fashion had to be designed. This concept is explained in chapter 4. The solid state implementation of the pipeline required two integrated circuits which were developed specially for the ZEUS calorimeter in collaboration with an electronics research institute and produced by industry. The design and construction of these devices and the detailed testing which has been performed for properties critical in the readout is covered in chapters 5 and 6. The whole pipelined readout is a complicated setup with many steps and collaborating systems. Its implementation and the information to operate it are covered in chapter 7. Finally the concepts presented and the applications discussed have been installed and tested on a test beam calibration experiment. There, the modules of the calorimeter have been calibrated. Chapter 8 presents results from these measurements which show excellent performance of the electronics as well as optimal properties of the calorimeter modules. (orig./HSI)

  7. Optimization of a microfluidic electrophoretic immunoassay using a Peltier cooler.

    Science.gov (United States)

    Mukhitov, Nikita; Yi, Lian; Schrell, Adrian M; Roper, Michael G

    2014-11-07

    Successful analysis of electrophoretic affinity assays depends strongly on the preservation of the affinity complex during separations. Elevated separation temperatures due to Joule heating promotes complex dissociation leading to a reduction in sensitivity. Affinity assays performed in glass microfluidic devices may be especially prone to this problem due to poor heat dissipation due to the low thermal conductivity of glass and the large amount of bulk material surrounding separation channels. To address this limitation, a method to cool a glass microfluidic chip for performing an affinity assay for insulin was achieved by a Peltier cooler localized over the separation channel. The Peltier cooler allowed for rapid stabilization of temperatures, with 21°C the lowest temperature that was possible to use without producing detrimental thermal gradients throughout the device. The introduction of cooling improved the preservation of the affinity complex, with even passive cooling of the separation channel improving the amount of complex observed by 2-fold. Additionally, the capability to thermostabilize the separation channel allowed for utilization of higher separation voltages than what was possible without temperature control. Kinetic CE analysis was utilized as a diagnostic of the affinity assay and indicated that optimal conditions were at the highest separation voltage, 6 kV, and the lowest separation temperature, 21°C, leading to 3.4% dissociation of the complex peak during the separation. These optimum conditions were used to generate a calibration curve and produced 1 nM limits of detection, representing a 10-fold improvement over non-thermostated conditions. This methodology of cooling glass microfluidic devices for performing robust and high sensitivity affinity assays on microfluidic systems should be amenable in a number of applications. Copyright © 2014 Elsevier B.V. All rights reserved.

  8. Enhanced Microfluidic Electromagnetic Measurements

    Science.gov (United States)

    Giovangrandi, Laurent (Inventor); Ricco, Antonio J. (Inventor); Kovacs, Gregory (Inventor)

    2015-01-01

    Techniques for enhanced microfluidic impedance spectroscopy include causing a core fluid to flow into a channel between two sheath flows of one or more sheath fluids different from the core fluid. Flow in the channel is laminar. A dielectric constant of a fluid constituting either sheath flow is much less than a dielectric constant of the core fluid. Electrical impedance is measured in the channel between at least a first pair of electrodes. In some embodiments, enhanced optical measurements include causing a core fluid to flow into a channel between two sheath flows of one or more sheath fluids different from the core fluid. An optical index of refraction of a fluid constituting either sheath flow is much less than an optical index of refraction of the core fluid. An optical property is measured in the channel.

  9. Bioanalysis in microfluidic devices.

    Science.gov (United States)

    Khandurina, Julia; Guttman, András

    2002-01-18

    Microfabricated bioanalytical devices (also referred to as laboratory-on-a-chip or micro-TAS) offer highly efficient platforms for simultaneous analysis of a large number of biologically important molecules, possessing great potential for genome, proteome and metabolome studies. Development and implementation of microfluidic-based bioanalytical tools involves both established and evolving technologies, including microlithography, micromachining, micro-electromechanical systems technology and nanotechnology. This article provides an overview of the latest developments in the key device subject areas and the basic interdisciplinary technologies. Important aspects of DNA and protein analysis, interfacing issues and system integration are all thoroughly discussed, along with applications for this novel "synergized" technology in high-throughput separations of biologically important molecules. This review also gives a better understanding of how to utilize these technologies as well as to provide appropriate technical solutions to problems perceived as being more fundamental.

  10. Spintronic microfluidic platform for biomedical and environmental applications

    Science.gov (United States)

    Cardoso, F. A.; Martins, V. C.; Fonseca, L. P.; Germano, J.; Sousa, L. A.; Piedade, M. S.; Freitas, P. P.

    2010-09-01

    Faster, more sensitive and easy to operate biosensing devices still are a need at important areas such as biomedical diagnostics, food control and environmental monitoring. Recently, spintronic-devices have emerged as a promising alternative to the existent technologies [1-3]. A number of advantages, namely high sensitivity, easy integration, miniaturization, scalability, robustness and low cost make these devices potentially capable of responding to the existent technological need. In parallel, the field of microfluidics has shown great advances [4]. Microfluidic systems allow the analysis of small sample volumes (from micro- down to pico-liters), often by automate sample processing with the ability to integrate several steps into a single device (analyte amplification, concentration, separation and/or labeling), all in a reduced assay time (minutes to hours) and affordable cost. The merging of these two technologies, magnetoresistive biochips and microfluidics, will enable the development of highly competitive devices. This work reports the integration of a magnetoresistive biochip with a microfluidic system inside a portable and autonomous electronic platform aiming for a fully integrated device. A microfluidic structure fabricated in polydimethylsiloxane with dimensions of W: 0.5mm, H: 0.1mm, L: 10mm, associated to a mechanical system to align and seal the channel by pressure is presented (Fig. 1) [5]. The goal is to perform sample loading and transportation over the chip and simultaneously control the stringency and uniformity of the wash-out process. The biochip output is acquired by an electronic microsystem incorporating the circuitry to control, address and read-out the 30 spin-valve sensors sequentially (Fig. 1) [2]. This platform is being applied to the detection of water-borne microbial pathogens (e.g. Salmonella and Escherichia coli) and genetic diseases diagnosis (e.g. cystic fibrosis) through DNA hybridization assays. Open chamber measurements were

  11. Digital Microfluidics Sample Analyzer

    Science.gov (United States)

    Pollack, Michael G.; Srinivasan, Vijay; Eckhardt, Allen; Paik, Philip Y.; Sudarsan, Arjun; Shenderov, Alex; Hua, Zhishan; Pamula, Vamsee K.

    2010-01-01

    Three innovations address the needs of the medical world with regard to microfluidic manipulation and testing of physiological samples in ways that can benefit point-of-care needs for patients such as premature infants, for which drawing of blood for continuous tests can be life-threatening in their own right, and for expedited results. A chip with sample injection elements, reservoirs (and waste), droplet formation structures, fluidic pathways, mixing areas, and optical detection sites, was fabricated to test the various components of the microfluidic platform, both individually and in integrated fashion. The droplet control system permits a user to control droplet microactuator system functions, such as droplet operations and detector operations. Also, the programming system allows a user to develop software routines for controlling droplet microactuator system functions, such as droplet operations and detector operations. A chip is incorporated into the system with a controller, a detector, input and output devices, and software. A novel filler fluid formulation is used for the transport of droplets with high protein concentrations. Novel assemblies for detection of photons from an on-chip droplet are present, as well as novel systems for conducting various assays, such as immunoassays and PCR (polymerase chain reaction). The lab-on-a-chip (a.k.a., lab-on-a-printed-circuit board) processes physiological samples and comprises a system for automated, multi-analyte measurements using sub-microliter samples of human serum. The invention also relates to a diagnostic chip and system including the chip that performs many of the routine operations of a central labbased chemistry analyzer, integrating, for example, colorimetric assays (e.g., for proteins), chemiluminescence/fluorescence assays (e.g., for enzymes, electrolytes, and gases), and/or conductometric assays (e.g., for hematocrit on plasma and whole blood) on a single chip platform.

  12. Parallel imaging microfluidic cytometer.

    Science.gov (United States)

    Ehrlich, Daniel J; McKenna, Brian K; Evans, James G; Belkina, Anna C; Denis, Gerald V; Sherr, David H; Cheung, Man Ching

    2011-01-01

    By adding an additional degree of freedom from multichannel flow, the parallel microfluidic cytometer (PMC) combines some of the best features of fluorescence-activated flow cytometry (FCM) and microscope-based high-content screening (HCS). The PMC (i) lends itself to fast processing of large numbers of samples, (ii) adds a 1D imaging capability for intracellular localization assays (HCS), (iii) has a high rare-cell sensitivity, and (iv) has an unusual capability for time-synchronized sampling. An inability to practically handle large sample numbers has restricted applications of conventional flow cytometers and microscopes in combinatorial cell assays, network biology, and drug discovery. The PMC promises to relieve a bottleneck in these previously constrained applications. The PMC may also be a powerful tool for finding rare primary cells in the clinic. The multichannel architecture of current PMC prototypes allows 384 unique samples for a cell-based screen to be read out in ∼6-10 min, about 30 times the speed of most current FCM systems. In 1D intracellular imaging, the PMC can obtain protein localization using HCS marker strategies at many times for the sample throughput of charge-coupled device (CCD)-based microscopes or CCD-based single-channel flow cytometers. The PMC also permits the signal integration time to be varied over a larger range than is practical in conventional flow cytometers. The signal-to-noise advantages are useful, for example, in counting rare positive cells in the most difficult early stages of genome-wide screening. We review the status of parallel microfluidic cytometry and discuss some of the directions the new technology may take. Copyright © 2011 Elsevier Inc. All rights reserved.

  13. Microsphere integrated microfluidic disk: synergy of two techniques for rapid and ultrasensitive dengue detection.

    Science.gov (United States)

    Hosseini, Samira; Aeinehvand, Mohammad M; Uddin, Shah M; Benzina, Abderazak; Rothan, Hussin A; Yusof, Rohana; Koole, Leo H; Madou, Marc J; Djordjevic, Ivan; Ibrahim, Fatimah

    2015-11-09

    The application of microfluidic devices in diagnostic systems is well-established in contemporary research. Large specific surface area of microspheres, on the other hand, has secured an important position for their use in bioanalytical assays. Herein, we report a combination of microspheres and microfluidic disk in a unique hybrid platform for highly sensitive and selective detection of dengue virus. Surface engineered polymethacrylate microspheres with carefully designed functional groups facilitate biorecognition in a multitude manner. In order to maximize the utility of the microspheres' specific surface area in biomolecular interaction, the microfluidic disk was equipped with a micromixing system. The mixing mechanism (microballoon mixing) enhances the number of molecular encounters between spheres and target analyte by accessing the entire sample volume more effectively, which subsequently results in signal amplification. Significant reduction of incubation time along with considerable lower detection limits were the prime motivations for the integration of microspheres inside the microfluidic disk. Lengthy incubations of routine analytical assays were reduced from 2 hours to 5 minutes while developed system successfully detected a few units of dengue virus. Obtained results make this hybrid microsphere-microfluidic approach to dengue detection a promising avenue for early detection of this fatal illness.

  14. High-Sensitivity Measurement of Density by Magnetic Levitation.

    Science.gov (United States)

    Nemiroski, Alex; Kumar, A A; Soh, Siowling; Harburg, Daniel V; Yu, Hai-Dong; Whitesides, George M

    2016-03-01

    This paper presents methods that use Magnetic Levitation (MagLev) to measure very small differences in density of solid diamagnetic objects suspended in a paramagnetic medium. Previous work in this field has shown that, while it is a convenient method, standard MagLev (i.e., where the direction of magnetization and gravitational force are parallel) cannot resolve differences in density mm) because (i) objects close in density prevent each other from reaching an equilibrium height due to hard contact and excluded volume, and (ii) using weaker magnets or reducing the magnetic susceptibility of the medium destabilizes the magnetic trap. The present work investigates the use of weak magnetic gradients parallel to the faces of the magnets as a means of increasing the sensitivity of MagLev without destabilization. Configuring the MagLev device in a rotated state (i.e., where the direction of magnetization and gravitational force are perpendicular) relative to the standard configuration enables simple measurements along the axes with the highest sensitivity to changes in density. Manipulating the distance of separation between the magnets or the lengths of the magnets (along the axis of measurement) enables the sensitivity to be tuned. These modifications enable an improvement in the resolution up to 100-fold over the standard configuration, and measurements with resolution down to 10(-6) g/cm(3). Three examples of characterizing the small differences in density among samples of materials having ostensibly indistinguishable densities-Nylon spheres, PMMA spheres, and drug spheres-demonstrate the applicability of rotated Maglev to measuring the density of small (0.1-1 mm) objects with high sensitivity. This capability will be useful in materials science, separations, and quality control of manufactured objects.

  15. High-sensitivity Cardiac Troponin Elevation after Electroconvulsive Therapy (ECT)

    Science.gov (United States)

    Duma, Andreas; Pal, Swatilika; Johnston, Joshua; Helwani, Mohammad A.; Bhat, Adithya; Gill, Bali; Rosenkvist, Jessica; Cartmill, Christopher; Brown, Frank; Miller, J. Philip; Scott, Mitchell G; Sanchez-Conde, Francisco; Jarvis, Michael; Farber, Nuri B.; Zorumski, Charles F.; Conway, Charles; Nagele, Peter

    2017-01-01

    Background While electroconvulsive therapy (ECT) is widely regarded as a life-saving and safe procedure, evidence regarding its effects on myocardial cell injury are sparse. The objective of this investigation was to determine incidence and magnitude of new cardiac troponin elevation after ECT using a novel high-sensitivity cardiac troponin I (hscTnI) assay. Methods This was a prospective cohort study in adult patients undergoing ECT in a single academic center (up to three ECT treatments per patient). The primary outcome was new hscTnI elevation after ECT, defined as an increase of hscTnI >100% after ECT compared to baseline with at least one value above the limit of quantification (10 ng/L). 12-lead ECG and hscTnI values were obtained prior to and 15–30 minutes after ECT; in a subset of patients an additional 2-hour hscTnI value was obtained. Results The final study population was 100 patients and a total of 245 ECT treatment sessions. Eight patients (8/100, 8%) experienced new hscTnI elevation after ECT with a cumulative incidence of 3.7% (9/245 treatments; one patient had two hscTnI elevations), two of whom had a non-ST-elevation myocardial infarction (incidence 2/245, 0.8%). Median hscTnI concentrations did not increase significantly after ECT. Tachycardia and/or elevated systolic blood pressure developed after approximately two thirds of ECT treatments. Conclusions ECT appears safe from a cardiac standpoint in a large majority of patients. A small subset of patients with pre-existing cardiovascular risk factors, however, may develop new cardiac troponin elevation after ECT, the clinical relevance of which is unclear in the absence of signs of myocardial ischemia. PMID:28166110

  16. High sensitivity pyrogen testing in water and dialysis solutions.

    Science.gov (United States)

    Daneshian, Mardas; Wendel, Albrecht; Hartung, Thomas; von Aulock, Sonja

    2008-07-20

    The dialysis patient is confronted with hundreds of litres of dialysis solution per week, which pass the natural protective barriers of the body and are brought into contact with the tissue directly in the case of peritoneal dialysis or indirectly in the case of renal dialysis (hemodialysis). The components can be tested for living specimens or dead pyrogenic (fever-inducing) contaminations. The former is usually detected by cultivation and the latter by the endotoxin-specific Limulus Amoebocyte Lysate Assay (LAL). However, the LAL assay does not reflect the response of the human immune system to the wide variety of possible pyrogenic contaminations in dialysis fluids. Furthermore, the test is limited in its sensitivity to detect extremely low concentrations of pyrogens, which in their sum result in chronic pathologies in dialysis patients. The In vitro Pyrogen Test (IPT) employs human whole blood to detect the spectrum of pyrogens to which humans respond by measuring the release of the endogenous fever mediator interleukin-1beta. Spike recovery checks exclude interference. The test has been validated in an international study for pyrogen detection in injectable solutions. In this study we adapted the IPT to the testing of dialysis solutions. Preincubation of 50 ml spiked samples with albumin-coated microspheres enhanced the sensitivity of the assay to detect contaminations down to 0.1 pg/ml LPS or 0.001 EU/ml in water or saline and allowed pyrogen detection in dialysis concentrates or final working solutions. This method offers high sensitivity detection of human-relevant pyrogens in dialysis solutions and components.

  17. Integrated lenses in polystyrene microfluidic devices

    KAUST Repository

    Fan, Yiqiang; Li, Huawei; Foulds, Ian G.

    2013-01-01

    This paper reports a new method for integrating microlenses into microfluidic devices for improved observation. Two demonstration microfluidic devices were provided which were fabricated using this new technique. The integrated microlenses were

  18. Manipulation of microfluidic droplets by electrorheological fluid

    KAUST Repository

    Zhang, Menying; Gong, Xiuqing; Wen, Weijia

    2009-01-01

    Microfluidics, especially droplet microfluidics, attracts more and more researchers from diverse fields, because it requires fewer materials and less time, produces less waste and has the potential of highly integrated and computer

  19. Microfluidic standardization: Past, present and future

    NARCIS (Netherlands)

    Heeren, H. van; Atkins, T.; Blom, M.; Bullema, J.E.; Tantra, R.; Verhoeven, D.; Verplanck, N.

    2016-01-01

    This paper addresses the issue of standardization in microfluidics. It contains the main points of an industry wide agreement about microfluidic port pitches and port nomenclature. It also addresses device classification and future steps.

  20. X-Ray Calorimeter Arrays for Astrophysics

    Science.gov (United States)

    Kilbourne, Caroline A.

    2009-01-01

    High-resolution x-ray spectroscopy is a powerful tool for studying the evolving universe. The grating spectrometers on the XMM and Chandra satellites started a new era in x-ray astronomy, but there remains a need for instrumentation that can provide higher spectral resolution with high throughput in the Fe-K band (around 6 keV) and can enable imaging spectroscopy of extended sources, such as supernova remnants and galaxy clusters. The instrumentation needed is a broad-band imaging spectrometer - basically an x-ray camera that can distinguish tens of thousands of x-ray colors. The potential benefits to astrophysics of using a low-temperature calorimeter to determine the energy of an incident x-ray photon via measurement of a small change in temperature was first articulated by S. H. Moseley over two decades ago. In the time since, technological progress has been steady, though full realization in an orbiting x-ray telescope is still awaited. A low-temperature calorimeter can be characterized by the type of thermometer it uses, and three types presently dominate the field. The first two types are temperature-sensitive resistors - semiconductors in the metal-insulator transition and superconductors operated in the superconducting-normal transition. The third type uses a paramagnetic thermometer. These types can be considered the three generations of x-ray calorimeters; by now each has demonstrated a resolving power of 2000 at 6 keV, but only a semiconductor calorimeter system has been developed to spaceflight readiness. The Soft X-ray Spectrometer on Astro-H, expected to launch in 2013, will use an array of silicon thermistors with I-IgTe x-ray absorbers that will operate at 50 mK. Both the semiconductor and superconductor calorimeters have been implemented in small arrays, kilo-pixel arrays of the superconducting calorimeters are just now being produced, and it is anticipated that much larger arrays will require the non-dissipative advantage of magnetic thermometers.

  1. Hollow micro string based calorimeter device

    DEFF Research Database (Denmark)

    2014-01-01

    positions so as to form a free released double clamped string in-between said two longitudinally distanced positions said micro-channel string comprising a microfluidic channel having a closed cross section and extending in the longitudinal direction of the hollow string, acoustical means adapted...

  2. Introducing wet aerosols into the static high sensitivity ICP (SHIP)

    Energy Technology Data Exchange (ETDEWEB)

    Scheffer, Andy; Engelhard, Carsten; Sperling, Michael; Buscher, Wolfgang [University of Muenster, Institute of Inorganic and Analytical Chemistry, Muenster (Germany)

    2007-08-15

    A demountable design of the static high sensitivity ICP (SHIP) for optical emission spectrometry is presented, and its use as an excitation source with the introduction of wet aerosols was investigated. Aerosols were produced by standard pneumatic sample introduction systems, namely a cross flow nebulizer, Meinhard nebulizer and PFA low flow nebulizer, which have been applied in conjunction with a double pass and a cyclonic spray chamber. The analytical capabilities of these sample introduction systems in combination with the SHIP system were evaluated with respect to the achieved sensitivity. It was found that a nebulizer tailored for low argon flow rates (0.3-0.5 L min{sup -1}) is best suited for the low flow plasma (SHIP). An optimization of all gas flow rates of the SHIP system with the PFA low flow nebulizer was carried out in a two-dimensional way with the signal to background ratio (SBR) and the robustness as optimization target parameters. Optimum conditions for a torch model with 1-mm injector tube were 0.25 and 0.36 L min{sup -1} for the plasma gas and the nebulizer gas, respectively. A torch model with a 2-mm injector tube was optimized to 0.4 L min{sup -1} for the plasma gas and 0.44 L min{sup -1} for the nebulizer gas. In both cases the SHIP system saves approximately 95% of the argon consumed by conventional inductively coupled plasma systems. The limits of detection were found to be in the low microgram per litre range and below for many elements, which was quite comparable to those of the conventional setup. Furthermore, the short-term stability and the wash out behaviour of the SHIP were investigated. Direct comparison with the conventional setup indicated that no remarkable memory effects were caused by the closed design of the torch. The analysis of a NIST SRM 1643e (Trace Elements in Water) with the SHIP yielded recoveries of 97-103% for 13 elements, measured simultaneously. (orig.)

  3. Metal ion-organic compound for high sensitive ESR dosimetry

    International Nuclear Information System (INIS)

    Hassan, G.M.; Ikeya, Motoji

    2000-01-01

    A systematic study to find a tissue equivalent and high sensitive dosimeter material has been made to stimulate the field of ESR dosimetry. Lithium acetate dihydrate (Li-Ac·2H 2 O:CH 3 COOLi·2H 2 O) and lithium phosphate (Li-phosphate:Li 3 PO 4 ) were irradiated by γ-rays to study radicals with (ESR) in addition to magnesium lactate (Mg-lactate (CH 3 CH(OH)COO) 2 Mg) doped with nominal pure lithium lactate (Mg(Li)-lactate) and lithium lactate (CH 3 CH(OH)COOLi) doped with Mg-lactate (Li(Mg)-lactate). A triplet spectrum with intensity ratio of 1:2:1 in Li-Ac·2H 2 O was ascribed to acetate radical which has g=2.0031±0.0004 and hyperfine splitting of A/gβ=2.12±0.1 mT. The Li-phosphate spectrum shows splitting due to anisotropic g-factors of g par =2.0190±0.0005 and g perp =1.9974±0.0004. Quartet spectra with the intensity ratio of 1:3:3:1 in Mg(Li)-lactate and Li(Mg)-lactate were ascribed to lactate radicals with g-factors of 2.0032 ± 0.0004 and 2.0029 ± 0.0004 and the intensity ratio of 1:3:3:1 and A/gβ=1.92±0.06 and 1.82 ± 0.06 mT, respectively. The response to γ-ray dose and the thermal stability as well as the effect of UV-illumination have been studied. The obtained number of free radicals per 100 eV (G-values) were 0.4 ± 0.13, 1.02 ± 0.31, 1.35 ± 0.35 and 0.78 ± 0 for Li-Ac.2H 2 O, Li-phosphate, Mg(Li)-lactate, and Li(Mg)-lactate, respectively. The lifetimes were estimated from Arrhenius plots to be approximately 2.0 ± 0.6, 50.7 ± 20 and 10 ± 3.5 years for Li-phosphate, Mg(Li)-lactate and Li(Mg)-lactate, respectively. The lifetime for Li-Ac·2H 2 O cannot be estimated because of the decomposition by heating

  4. Recent developments in crystal calorimeters (featuring the CMS PbWO4 electromagnetic calorimeter)

    International Nuclear Information System (INIS)

    Gascon-Shotkin, S.

    2003-01-01

    In the mass range of 110-150 GeV the favored process for Higgs boson detection via p-p collisions is via its decay into two photons, which demands a very high-resolution electromagnetic calorimeter. This physics goal plus the Large Hadron Calorimeter (LHC)-imposed design constraints of 25ns bunch spacing and a hostile radiation environment have led the Compact Muon Solenoid (CMS) collaboration to the choice of lead tungstate (PbWO 4 ) crystals. These factors plus the presence of a 4T magnetic field and the relatively low room-temperature scintillation photon yield of PbWO 4 make photo detection a real challenge, which CMS has met via the choice of devices providing gain amplification: Avalanche photodiodes (APD) in the central barrel region and vacuum phototriodes (VPT) in the forward and backward endcap regions. In the past year the CMS electromagnetic calorimeter has entered the construction phase. We review progress in the areas of crystals, barrel and endcap photo detection devices, plans for detector calibration as well as the status of assembly and quality control. We also invoke relevant developments in other crystal calorimeters currently in operation or under development. Crystal calorimeters remain the medium of choice for precision energy and position measurements in high energy physics

  5. Sources of compensation in hadronic calorimeters

    International Nuclear Information System (INIS)

    Goodman, M.S.; Gabriel, T.A.; Di Ciaccio, A.; Wilson, R.

    1988-12-01

    Monte Carlo simulations are presented using the CALOR code system to study the design of a large hybrid hadron calorimeter system employing a warm liquid active medium (tetramethylsilane, Si(CH 3 ) 4 ) and uranium plates in addition to a conventional Fe/plastic system. In the system described here, the uranium provides partial compensation by suppressing the electromagnetic cascade produced by incident electrons due to sampling inefficiencies. The results of the simulations also indicate that significant compensation is achieved (given small enough saturation) due to low energy recoil protons produced in collisions with low energy (1--20 MeV) cascade and fission neutrons in the active medium. Both compensation mechanisms are important to help balance the response of a calorimeter to incident electrons and hadrons, that is, to achieve a ratio of pulse heights (e/h ∼ 1) which will lead to the best energy resolution. 17 refs., 4 figs., 2 tabs

  6. Precision timing with liquid ionization calorimeters

    International Nuclear Information System (INIS)

    Benary, O.; Cannon, S.; Cleland, W.; Ferguson, I.; Finley, C.; Gordeev, A.; Gordon, H.; Kistenev, E.; Kroon, P.; Letchouk, M.; Lissauer, D.; Ma, H.; Makowiecki, D.; Maslennikov, A.; McCorkle, S.; Onoprienko, D.; Onuchin, A.; Oren, Y.; Panin, V.; Parsons, J.; Rabel, J.; Radeka, V.; Rogers, L.; Rahm, D.; Rescia, S.; Rutherfoord, J.; Seman, M.; Smith, M.; Sondericker, J. III; Steiner, R.; Stephani, D.; Stern, E.; Stumer, I.; Takai, H.; Themann, H.; Tikhonov, Y.

    1993-01-01

    We present timing measurements performed with a liquid krypton electromagnetic accordion calorimeter, measured in an electron beam over an energy range of 5-20 GeV. A novel discriminator with an amplitude-independent timing response was used to extract the inherently accurate timing information from the calorimeter. As expected, the timing resolution σ τ is observed to vary inversely with the signal amplitude, which is proportional to the deposited energy E. We measure a resolution of σ τ =4.15±0.06 GeV ns/E for a sum of 5x5 towers with dimensions 2.7x2.5 cm 2 each. From this we deduce that the timing resolution for an individual tower is approximately 0.8 GeV ns/E. (orig.)

  7. Work on a ATLAS tile calorimeter Barrel

    CERN Multimedia

    Laurent Guiraud

    2000-01-01

    The Tile Calorimeter is designed as one barrel and two extended barrel hadron parts. The calorimeter consists of a cylindrical structure with inner and outer radius of 2280 and 4230 mm respectively. The barrel part is 5640 mm in length along the beam axis, while each of the extended barrel cylinders is 2910 mm long. Each detector cylinder is built of 64 independent wedges along the azimuthal direction. Between the barrel and the extended barrels there is a gap of about 600 mm, which is needed for the Inner Detector and the Liquid Argon cables, electronics and services. The barrel covers the region -1.0

  8. The ATLAS Tile Calorimeter Performance at LHC

    CERN Document Server

    Molander, S; The ATLAS collaboration

    2013-01-01

    The Tile Calorimeter (TileCal) is the central section of the hadronic calorimeter of the ATLAS experiment at LHC. The TileCal pays a major role in detecting hadrons, jets, hadronic decays of tau leptons and measuring the missing transverse energy. Due to the very good signal to noise ratio it assists the muon spectrometer in the identification and reconstruction of muons, which are also a tool for the in situ energy scale validation. The results presented here stem from the data collection in dedicated calibration runs, in cosmic rays data-taking and in LHC collisions along 3 years of operation. The uniformity, stability and precision of the energy scale, the time measurement capabilities and the robustness of the performance against pile-up are exposed through the usage of hadronic and muon final states and confirm the design expectations.

  9. LHCb: Upgrade of the LHCb calorimeter electronics

    CERN Multimedia

    Mauricio Ferre, J

    2013-01-01

    The LHCb collaboration foresees a major upgrade of the detector for the high luminosity run that should take place after 2018. Apart from the increase of the instantaneous luminosity at the interaction point of the experiment, one of the major ingredients of this upgrade is a full readout at 40MHz of the sub-detectors and the acquisition of the data by a large farm of PC. The trigger will be done by this farm and should increase the overall trigger efficiency with respect to the current detector, especially in hadronic B meson decays. A general overview of the modifications foreseen to the calorimeter system and the integration of the electromagnetic and hadronic calorimeters in this new scheme will be described.

  10. Hermeticity of three cryogenic calorimeter geometries

    International Nuclear Information System (INIS)

    Strovink, M.; Wormersley, W.J.; Forden, G.E.

    1989-04-01

    We calculate the effect of cracks and dead material on resolution in three simplified cryogenic calorimeter geometries, using a crude approximation that neglects transverse shower spreading and considers only a small set of incident angles. For each dead region, we estimate the average unseen energy using a shower parametrization, and relate it to resolution broadening using a simple approximation that agrees with experimental data. Making reasonable and consistent assumptions on cryostat wall thicknesses, we find that the effects of cracks and dead material dominate the expected resolution in the region where separate ''barrel'' and ''end'' cryostats meet. This is particularly true for one geometry in which the end calorimeter caps the barrel and also protrudes into the hole within it. We also find that carefully designed auxiliary ''crack filler'' detectors can substantially reduce the loss of resolution in these areas. 6 figs

  11. The ATLAS Electromagnetic Calorimeter Calibration Workshop

    CERN Multimedia

    Hong Ma; Isabelle Wingerter

    The ATLAS Electromagnetic Calorimeter Calibration Workshop took place at LAPP-Annecy from the 1st to the 3rd of October; 45 people attended the workshop. A detailed program was setup before the workshop. The agenda was organised around very focused presentations where questions were raised to allow arguments to be exchanged and answers to be proposed. The main topics were: Electronics calibration Handling of problematic channels Cluster level corrections for electrons and photons Absolute energy scale Streams for calibration samples Calibration constants processing Learning from commissioning Forty-five people attended the workshop. The workshop was on the whole lively and fruitful. Based on years of experience with test beam analysis and Monte Carlo simulation, and the recent operation of the detector in the commissioning, the methods to calibrate the electromagnetic calorimeter are well known. Some of the procedures are being exercised in the commisssioning, which have demonstrated the c...

  12. Instrumented module of the ATLAS tile calorimeter

    CERN Multimedia

    Laurent Guiraud

    1998-01-01

    The ATLAS tile calorimeter consists of steel absorber plates interspersed with plastic scintillator tiles. Interactions of high-energy hadrons in the plates transform the incident energy into a 'hadronic shower'. When shower particles traverse the scintillating tiles, the latter emit an amount of light proportional to the incident energy. This light is transmitted along readout fibres to a photomultiplier, where a detectable electrical signal is produced. These pictures show one of 64 modules or 'wedges' of the barrel part of the tile calorimeter, which are arranged to form a cylinder around the beam axis. The wedge has been instrumented with scintillators and readout fibres. Photos 03, 06: Checking the routing of the readout fibres into the girder that houses the photomultipliers. Photo 04: A view of the fibre bundles inside the girder.

  13. The new ATLAS Fast Calorimeter Simulation

    CERN Document Server

    Jacka, Petr; The ATLAS collaboration

    2018-01-01

    With the huge amount of data collected with ATLAS, there is a need to produce a large number of simulated events. These productions are very CPU and time consuming when using the full GEANT4 simulation. FastCaloSim is a program to quickly simulate the ATLAS calorimeter response, based on a parameterization of the GEANT4 energy deposits of several kinds of particles in a grid of energy and eta. A new version of FastCaloSim is under development and its integration into the ATLAS simulation infrastructure is ongoing. The use of machine learning techniques improves the performance and decreases the memory usage. Dedicated parameterizations for the forward calorimeters are being studied. First results of the new FastCaloSim show substantial improvements of the description of energy and shower shape variables, including the variables for jet substructure.

  14. The dry heat exchanger calorimeter system

    International Nuclear Information System (INIS)

    Renz, D.P.; Wetzel, J.R.; James, S.J.; Kasperski, P.W.; Duff, M.F.

    1991-01-01

    A radiometric isothermal heat flow calorimeter and preconditioner system that uses air instead of water as the heat exchange medium has been developed at Mound. The dry heat exchanger calorimeter is 42 inches high by 18 inches in diameter and the preconditioner is a 22 inch cube, making it extremely compact compared to existing units. The new system is ideally suited for transportable, stand-alone, or glovebox applications. Preliminary tests of the system have produced sample measurements with standard deviations less than 0.25% and sample errors less than 0.50%. These tests have shown that the dry heat exchanger system will yield acceptance data with an accuracy comparable to those of Mound water bath systems now in use. 4 figs., 1 tab

  15. Muon Detection Based on a Hadronic Calorimeter

    CERN Document Server

    Ciodaro, T; Abreu, R; Achenbach, R; Adragna, P; Aharrouche, M; Aielli, G; Al-Shabibi, A; Aleksandrov, I; Alexandrov, E; Aloisio, A; Alviggi, M G; Amorim, A; Amram, N; Andrei, V; Anduaga, X; Angelaszek, D; Anjos, N; Annovi, A; Antonelli, S; Anulli, F; Apolle, R; Aracena, I; Ask, S; Åsman, B; Avolio, G; Baak, M; Backes, M; Backlund, S; Badescu, E; Baines, J; Ballestrero, S; Banerjee, S; Bansil, H S; Barnett, B M; Bartoldus, R; Bartsch, V; Batraneanu, S; Battaglia, A; Bauss, B; Beauchemin, P; Beck, H P; Bee, C; Begel, M; Behera, P K; Bell, P; Bell, W H; Bellagamba, L; Bellomo, M; Ben Ami, S; Bendel, M; Benhammou, Y; Benslama, K; Berge, D; Bernius, C; Berry, T; Bianco, M; Biglietti, M; Blair, R E; Bogaerts, A; Bohm, C; Boisvert, V; Bold, T; Bondioli, M; Borer, C; Boscherini, D; Bosman, M; Bossini, E; Boveia, A; Bracinik, J; Brandt, A G; Brawn, I P; Brelier, B; Brenner, R; Bressler, S; Brock, R; Brooks, W K; Brown, G; Brunet, S; Bruni, A; Bruni, G; Bucci, F; Buda, S; Burckhart-Chromek, D; Buscher, V; Buttinger, W; Calvet, S; Camarri, P; Campanelli, M; Canale, V; Canelli, F; Capasso, L; Caprini, M; Caracinha, D; Caramarcu, C; Cardarelli, R; Carlino, G; Casadei, D; Casado, M P; Cattani, G; Cerri, A; Cerrito, L; Chapleau, B; Childers, J T; Chiodini, G; Christidi, I; Ciapetti, G; Cimino, D; Ciobotaru, M; Coccaro, A; Cogan, J; Collins, N J; Conde Muino, P; Conidi, C; Conventi, F; Corradi, M; Corso-Radu, A; Coura Torres, R; Cranmer, K; Crescioli, F; Crone, G; Crupi, R; Cuenca Almenar, C; Cummings, J T; Curtis, C J; Czyczula, Z; Dam, M; Damazio, D; Dao, V; Darlea, G L; Davis, A O; De Asmundis, R; De Pedis, D; De Santo, A; de Seixas, J M; Degenhardt, J; Della Pietra, M; Della Volpe, D; Demers, S; Demirkoz, B; Di Ciaccio, A; Di Mattia, A; Di Nardo, R; Di Simone, A; Diaz, M A; Dietzsch, T A; Dionisi, C; Dobson, E; Dobson, M; dos Anjos, A; Dotti, A; Dova, M T; Drake, G; Dufour, M-A; Dumitru, I; Eckweiler, S; Ehrenfeld, W; Eifert, T; Eisenhandler, E; Ellis, K V; Ellis, N; Emeliyanov, D; Enoque Ferreira de Lima, D; Ermoline, Y; Ernst, J; Etzion, E; Falciano, S; Farrington, S; Farthouat, P; Faulkner , P J W; Fedorko, W; Fellmann, D; Feng, E; Ferrag, S; Ferrari, R; Ferrer, M L; Fiorini, L; Fischer, G; Flowerdew, M J; Fonseca Martin, T; Francis, D; Fratina, S; French, S T; Front, D; Fukunaga, C; Gadomski, S; Garelli, N; Garitaonandia Elejabarrieta, H; Gaudio, G; Gee, C N P; George, S; Giagu, S; Giannetti, P; Gillman, A R; Giorgi, M; Giunta, M; Giusti, P; Goebel, M; Gonçalo, R; Gonzalez Silva, L; Göringer, C; Gorini, B; Gorini, E; Grabowska-Bold, I; Green, B; Groll, M; Guida, A; Guler, H; Haas, S; Hadavand, H; Hadley, D R; Haller, J; Hamilton, A; Hanke, P; Hansen, J R; Hasegawa, S; Hasegawa, Y; Hauser, R; Hayakawa, T; Hayden, D; Head, S; Heim, S; Hellman, S; Henke, M; Hershenhorn, A; Hidvégi, A; Hillert, S; Hillier, S J; Hirayama, S; Hod, N; Hoffmann, D; Hong, T M; Hryn'ova, T; Huston, J; Iacobucci, G; Igonkina, O; Ikeno, M; Ilchenko, Y; Ishikawa, A; Ishino, M; Iwasaki, H; Izzo, V; Jez, P; Jimenez Otero, S; Johansen, M; Johns, K; Jones, G; Joos, M; Kadlecik, P; Kajomovitz, E; Kanaya, N; Kanega, F; Kanno, T; Kapliy, A; Kaushik, V; Kawagoe, K; Kawamoto, T; Kazarov, A; Kehoe, R; Kessoku, K; Khomich, A; Khoriauli, G; Kieft, G; Kirk, J; Klemetti, M; Klofver, P; Klous, S; Kluge, E-E; Kobayashi, T; Koeneke, K; Koletsou, I; Koll, J D; Kolos, S; Kono, T; Konoplich, R; Konstantinidis, N; Korcyl, K; Kordas, K; Kotov, V; Kowalewski, R V; Krasznahorkay, A; Kraus, J; Kreisel, A; Kubota, T; Kugel, A; Kunkle, J; Kurashige, H; Kuze, M; Kwee, R; Laforge, B; Landon, M; Lane, J; Lankford, A J; Laranjeira Lima, S M; Larner, A; Leahu, L; Lehmann Miotto, G; Lei, X; Lellouch, D; Levinson, L; Li, S; Liberti, B; Lilley, J N; Linnemann, J T; Lipeles, E; Lohse, T; Losada, M; Lowe, A; Luci, C; Luminari, L; Lundberg, J; Lupu, N; Machado Miguéns, J; Mackeprang, R; Maettig, S; Magnoni, L; Maiani, C; Maltrana, D; Mangeard, P-S; Männer, R; Mapelli, L; Marchese, F; Marino, C; Martin, B; Martin, B T; Martin, T; Martyniuk, A; Marzano, F; Masik, J; Mastrandrea, P; Matsushita, T; McCarn, A; Mechnich, J; Medinnis, M; Meier, K; Melachrinos, C; Mendoza Nava, L M; Merola, L; Messina, A; Meyer, C P; Middleton, R P; Mikenberg, G; Mills, C M; Mincer, A; Mineev, M; Misiejuk, A; Moa, T; Moenig, K; Monk, J; Monticelli, F; Mora Herrera, C; Morettini, P; Morris, J D; Müller, F; Munwes, Y; Murillo Garcia, R; Nagano, K; Nagasaka, Y; Navarro, G A; Negri, A; Nelson, S; Nemethy, P; Neubauer, M S; Neusiedl, A; Newman, P; Nisati, A; Nomoto, H; Nozaki, M; Nozicka, M; Nurse, E; Ochando, C; Ochi, A; Oda, S; Oh, A; Ohm, C; Okumura, Y; Olivito, D; Omachi, C; Osculati, B; Oshita, H; Ospanov, R; Owen, M A; Özcan, V E; Ozone, K; Padilla, C; Panes, B; Panikashvili, N; Paramonov, A; Parodi, F; Pasqualucci, E; Pastore, F; Patricelli, S; Pauly, T; Perera, V J O; Perez, E; Petcu, M; Petersen, B A; Petersen, J; Petrolo, E; Phan, A; Piegaia, R; Pilkington, A; Pinder, A; Poddar, S; Polini, A; Pope, B G; Potter, C T; Primavera, M; Prokoshin, F; Ptacek, E; Qian, W; Quinonez, F; Rajagopalan, S; Ramos Dos Santos Neves, R; Reinherz-Aronis, E; Reinsch, A; Renkel, P; Rescigno, M; Rieke, S; Riu, I; Robertson, S H; Robinson, M; Rodriguez, D; Roich, A; Romeo, G; Romero, R; Roos, L; Ruiz Martinez, A; Ryabov, Y; Ryan, P; Saavedra, A; Safai Tehrani, F; Sakamoto, H; Salamanna, G; Salamon, A; Saland, J; Salnikov, A; Salvatore, F; Sankey, D P C; Santamarina, C; Santonico, R; Sarkisyan-Grinbaum, E; Sasaki, O; Savu, D; Scannicchio, D A; Schäfer, U; Scharf, V L; Scheirich, D; Schiavi, C; Schlereth, J; Schmitt, K; Schroder, C; Schroer, N; Schultz-Coulon, H-C; Schwienhorst, R; Sekhniaidze, G; Sfyrla, A; Shamim, M; Sherman, D; Shimojima, M; Shochet, M; Shooltz, D; Sidoti, A; Silbert, O; Silverstein, S; Sinev, N; Siragusa, G; Sivoklokov, S; Sjoen, R; Sjölin, J; Slagle, K; Sloper, J E; Smith, B C; Soffer, A; Soloviev, I; Spagnolo, S; Spiwoks, R; Staley, R J; Stamen, R; Stancu, S; Steinberg, P; Stelzer, J; Stockton, M C; Straessner, A; Strauss, E A; Strom, D; Su, D; Sugaya, Y; Sugimoto, T; Sushkov, S; Sutton, M R; Suzuki, Y; Taffard, A; Taiblum, N; Takahashi, Y; Takeda, H; Takeshita, T; Tamsett, M; Tan, C L A; Tanaka, S; Tapprogge, S; Tarem, S; Tarem, Z; Taylor, C; Teixeira-Dias, P; Thomas, J P; Thompson, P D; Thomson, M A; Tokushuku, K; Tollefson, K; Tomoto, M; Topfel, C; Torrence, E; Touchard, F; Traynor, D; Tremblet, L; Tricoli, A; Tripiana, M; Triplett, N; True, P; Tsiakiris, M; Tsuno, S; Tuggle, J; Ünel, G; Urquijo, P; Urrejola, P; Usai, G; Vachon, B; Vallecorsa, S; Valsan, L; Vandelli, W; Vari, R; Vaz Gil Lopes, L; Veneziano, S; Ventura, A; Venturi, N; Vercesi, V; Vermeulen, J C; Volpi, G; Vorwerk, V; Wagner, P; Wang, M; Warburton, A; Watkins, P M; Watson, A T; Watson, M; Weber, P; Weidberg, A R; Wengler, T; Werner, P; Werth, M; Wessels, M; White, M; Whiteson, D; Wickens, F J; Wiedenmann, W; Wielers, M; Winklmeier, F; Woods, K S; Wu, S-L; Wu, X; Xaplanteris Karampatsos, L; Xella, S; Yakovlev, A; Yamazaki, Y; Yang, U; Yasu, Y; Yuan, L; Zaitsev, A; Zanello, L; Zhang, H; Zhang, J; Zhao, L; Zobernig, H; zur Nedden, M

    2010-01-01

    The ATLAS Tile hadronic calorimeter (TileCal) provides highly-segmented energy measurements of incoming particles. The information from TileCal's last segmentation layer can assist in muon tagging and it is being considered for a near future upgrade of the level-one trigger, mainly for rejecting triggers due to cavern background at the barrel region. A muon receiver for the TileCal muon signals is being designed in order to interface with the ATLAS level-one trigger. This paper addresses the preliminary studies concerning the muon discrimination capability for the muon receiver. Monte Carlo simulations for single muons from the interaction point were used to study the effectiveness of hadronic calorimeter information on muon detection.

  16. LYSO crystal calorimeter readout with silicon photomultipliers

    Energy Technology Data Exchange (ETDEWEB)

    Berra, A., E-mail: alessandro.berra@gmail.com [Università degli Studi dell' Insubria (Italy); INFN sezione di Milano Bicocca (Italy); Bonvicini, V. [INFN sezione di Trieste (Italy); Cecchi, C.; Germani, S. [INFN sezione di Perugia (Italy); Guffanti, D. [Università degli Studi dell' Insubria (Italy); Lietti, D. [Università degli Studi dell' Insubria (Italy); INFN sezione di Milano Bicocca (Italy); Lubrano, P.; Manoni, E. [INFN sezione di Perugia (Italy); Prest, M. [Università degli Studi dell' Insubria (Italy); INFN sezione di Milano Bicocca (Italy); Rossi, A. [INFN sezione di Perugia (Italy); Vallazza, E. [INFN sezione di Trieste (Italy)

    2014-11-01

    Large area Silicon PhotoMultipliers (SiPMs) are the new frontier of the development of readout systems for scintillating detectors. A SiPM consists of a matrix of parallel-connected silicon micropixels operating in limited Geiger–Muller avalanche mode, and thus working as independent photon counters with a very high gain (∼10{sup 6}). This contribution presents the performance in terms of linearity and energy resolution of an electromagnetic homogeneous calorimeter composed of 9∼18X{sub 0} LYSO crystals. The crystals were readout by 36 4×4 mm{sup 2} SiPMs (4 for each crystal) produced by FBK-irst. This calorimeter was tested at the Beam Test Facility at the INFN laboratories in Frascati with a single- and multi-particle electron beam in the 100–500 MeV energy range.

  17. Upgrading the ATLAS Tile Calorimeter Electronics

    Directory of Open Access Journals (Sweden)

    Carrió Fernando

    2013-11-01

    Full Text Available This work summarizes the status of the on-detector and off-detector electronics developments for the Phase 2 Upgrade of the ATLAS Tile Calorimeter at the LHC scheduled around 2022. A demonstrator prototype for a slice of the calorimeter including most of the new electronics is planned to be installed in ATLAS in the middle of 2014 during the first Long Shutdown. For the on-detector readout, three different front-end boards (FEB alternatives are being studied: a new version of the 3-in-1 card, the QIE chip and a dedicated ASIC called FATALIC. The Main Board will provide communication and control to the FEBs and the Daughter Board will transmit the digitized data to the off-detector electronics in the counting room, where the super Read-Out Driver (sROD will perform processing tasks on them and will be the interface to the trigger levels 0, 1 and 2.

  18. Upgrade of the ATLAS Tile Calorimeter Electronics

    CERN Document Server

    Carrio, F; The ATLAS collaboration

    2014-01-01

    This presentation summarizes the status of the on-detector and off-detector electronics developments for the Phase II Upgrade of the ATLAS Tile Calorimeter at the LHC scheduled around 2024. A demonstrator prototype for a slice of the calorimeter including most of the new electronics is planned to be installed in ATLAS in middle 2014 during the Long Shutdown. For the on-detector readout, three different front-end boards (FEB) alternatives are being studied: a new version of the 3-in-1 card, the QIE chip and a dedicated ASIC called FATALIC. The MainBoard will provide communication and control to the FEBs and the DaughterBoard will transmit the digitized data to the off-detector electronics in the counting room, where the sROD will perform processing tasks on them.

  19. Upgrading the ATLAS Tile Calorimeter Electronics

    CERN Document Server

    Carrio, F

    2013-01-01

    This work summarizes the status of the on-detector and off-detector electronics developments for the Phase II Upgrade of the ATLAS Tile Calorimeter at the LHC scheduled around 2022. A demonstrator prototype for a slice of the calorimeter including most of the new electronics is planned to be installed in ATLAS in middle 2014 during the Long Shutdown. For the on-detector readout, three different front-end boards (FEB) alternatives are being studied: a new version of the 3-in-1 card, the QIE chip and a dedicated ASIC called FATALIC. The MainBoard will provide communication and control to the FEBs and the DaughterBoard will transmit the digitized data to the off-detector electronics in the counting room, where the sROD will perform processing tasks on them.

  20. Measurements with the Chalk River Calorimeters

    International Nuclear Information System (INIS)

    Boyd, A.W.

    1970-01-01

    The Chalk River calorimeters were designed to measure the absorbed dose rate in reactors in materials such as graphite, polyethylene and beryllium in the range 0.01-1 Wg -1 . To eliminate heaters in the sample they were made to operate adiabatically, or more accurately quasi-adiabatically since there is no heater on the jacket. Both the sample and jacket temperatures are recorded from the time of insertion in the reactor flux and the absorbed dose rate is calculated from these data. The advantages of this type of calorimeter are the ease of construction and the absence of a sample heater. The disadvantage is that dose rates below ~ 10 mWg -1 cannot be determined accurately

  1. The new UA1 calorimeter trigger

    International Nuclear Information System (INIS)

    Eisenhandler, E.

    1988-01-01

    The new UA1 first-level calorimeter trigger processor is described, with emphasis on the fast two-dimensional electromagnetic cluster-finding that is its most novel feature. This processor is about five times more powerful than its predecessor, and makes extensive use of pipelining techniques. It allows multiple combinations of triggers on electromagnetic showers, hadronic jets and energy sums, including a total-energy veto of multiple interactions and a full vector sum of missing transverse energy. (author)

  2. The ZEUS second level calorimeter trigger

    International Nuclear Information System (INIS)

    Jong, S.J. de.

    1990-01-01

    ZEUS is a detector for the HERA ep collider, consisting of several large components. The most important being the inner tracking detectors, which are positioned nearest to the interaction point, the calorimeter surrounding the inner tracking detectors and the muon detectors on the outside of the experimental setup. Each component will deliver a vast amount of information. In order to keep this information manageable, data is preprocessed and condensed per component and then combined to obtain the final global trigger result. The main subject of this thesis is the second level calorimeter trigger processor of the ZEUS detector. In order to be able to reject the unwanted events passing the first level, the topological event signature will have to be used at the second level. The most demanding task of the second level is the recognition of local energy depositions corresponding to isolated electrons and hadron jets. Also part of the work performed by the first level will be repeated with a higher level of accuracy. Additional information not available to the first level trigger will be processed and will be made available to the global second level trigger decision module. For the second level calorimeter trigger processor a special VME module, containing two transputers, has been developed. The second level calorimeter trigger algorithm described in this thesis was tested with simulated events, that were tracked through a computer simulation of the ZEUS detector. A part of this thesis is therefore devoted to the description of the various Monte Carlo models and the justification of the way in which they were used. (author). 132 refs.; 76 figs.; 18 tabs

  3. Isothermal calorimeter for reactor radiation dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Radak, B; Markovic, V [Institute of Nuclear Sciences Boris Kidric, Odeljenje za radijacionu hemiju, Vinca, Beograd (Serbia and Montenegro)

    1961-12-15

    An isothermal calorimeter with thermistors for measuring absorbed dose rates from 10{sup 4}-5-6.10{sup 5} rad/h in reactor experimental holes has been designed. A kinetics method for determining the equilibrium temperature difference has been developed, and its application in isothermal calorimetry proved. The expected accuracy in measurements within {+-} 2-5% has been proved by measurements carried out in the reactor. Some data obtained by measurements in the reactor RA are presented (author)

  4. Homogeneous scintillating LKr/Xe calorimeters

    Energy Technology Data Exchange (ETDEWEB)

    Chen, M.; Mullins, M.; Pelly, D.; Shotkin, S.; Sumorok, K. (Lab. for Nuclear Science, MIT, Cambridge, MA (United States)); Akyuz, D.; Chen, E.; Gaudreau, M.P.J. (Plasma Fusion Center, MIT, Cambridge, MA (United States)); Bolozdynya, A.; Tchernyshev, V.; Goritchev, P.; Khovansky, V.; Koutchenkov, A.; Kovalenko, A.; Lebedenko, V.; Vinogradov, V.; Gusev, L.; Sheinkman, V. (ITEP, Moscow (Russia)); Krasnokutsky, R.N.; Shuvalov, R.S.; Fedyakin, N.N.; Sushkov, V. (IHEP, Serpukhov (Russia)); Akopyan, M. (Inst. for Nuclear Research, Moscow (Russia)); Doke, T.; Kikuchi, J.; Hitachi, A.; Kashiwagi, T. (Science and Eng. Res. Lab., Waseda Univ., Tokyo (Japan)); Masuda, K.; Shibamura, E. (Saitama Coll. of Health (Japan)); Ishida, N. (Seikei Univ. (Japan)); Sugimoto, S. (INS, Univ. Tokyo (Japan))

    1993-03-20

    Recent R and D work on full length scintillating homogeneous liquid xenon/krypton (LXe/Kr) cells has established the essential properties for precision EM calorimeters: In-situ calibration using [alpha]'s, radiation hardness as well as the uniformity required for [delta]E/E[approx equal]0.5% for e/[gamma]'s above 50 GeV. (orig.).

  5. The CDF central and endwall hadron calorimeter

    International Nuclear Information System (INIS)

    Bertolucci, S.; Cordelli, M.; Eposito, B.; Curatolo, M.; Giromini, P.; Miscetti, S.; Sansoni, A.; Barnes, V.E.; Di Virgilio, A.; Garfinkel, A.F.; Kuhlmann, S.E.; Laasanen, A.T.

    1988-01-01

    The CDF central and endwall hadron calorimeter covers the polar region between 30 0 and 150 0 and a full 2π in azimuth. It consists of 48 steel-scintillator central modules with 2.5 cm sampling and 48 steel-scintillator endwall modules with 5.0 cm sampling. A general description of the detector is given. Calibration techniques and performance are discussed. Some results of the test beam studies are shown. (orig.)

  6. Measurement of ultrasound power using a calorimeter

    Science.gov (United States)

    Morgado, G.; Miqueleti, S.; Costa-Felix, R. P. B.

    2018-03-01

    This paper presents a comparison between the ultrasound power of a 1 MHz therapy equipment on the water using a calorimeter and a radiation force balance. For a range of 5 to 10 W, the results presented a normalized error less than 1, disclosing compatibility of the results from the developed system and the radiation force balance. The calorimetric method might be used as a faster and cheaper means for the verification of the ultrasonic power emitted by an equipment for physiotherapeutic treatment.

  7. Prototype calorimeters for the NA3 experiment

    CERN Multimedia

    1975-01-01

    The NA3 Experiment was set-up on the North Area of the SPS by the CERN/ Ecole Polytechnique/College de France/ Orsay/Saclay Collaboration, to study high transverse momentum leptons and hadrons from hadron collisions. The calorimeters measured the energy of hadrons (prototype on the right) and leptons (prototype on the left). They used a new type of plastic scintillator (plexipop). (see CERN Courier of November 1975) energy (prototype on the right)

  8. Upgrade of the ATLAS Tile Calorimeter Electronics

    International Nuclear Information System (INIS)

    Carrió, F

    2015-01-01

    The Tile Calorimeter (TileCal) is the hadronic calorimeter covering the central region of the ATLAS experiment at LHC. The TileCal readout consists of about 10000 channels. The bulk of its upgrade will occur for the High Luminosity LHC phase (Phase-II) where the peak luminosity will increase 5 times compared to the design luminosity (10 34 cm −2 s −1 ) but with maintained energy (i.e. 7+7 TeV). An additional increase of the average luminosity with a factor of 2 can be achieved by luminosity levelling. This upgrade is expected to happen around 2024. The TileCal upgrade aims at replacing the majority of the on- and off- detector electronics to the extent that all calorimeter signals will be digitized and sent to the off-detector electronics in the counting room. To achieve the required reliability, redundancy has been introduced at different levels. Three different options are presently being investigated for the front-end electronic upgrade. Extensive test beam studies will determine which option will be selected. 10 Gbps optical links are used to read out all digitized data to the counting room while 5 Gbps down-links are used for synchronization, configuration and detector control. For the off-detector electronics a pre-processor (sROD) is being developed, which takes care of the initial trigger processing while temporarily storing the main data flow in pipeline and derandomizer memories. One demonstrator prototype module with the new calorimeter module electronics, but still compatible with the present system, is planned to be inserted in ATLAS this year

  9. Performance test of a TMS calorimeter

    International Nuclear Information System (INIS)

    Wild, B.

    1986-10-01

    Performance tests of a first calorimeter module using the room temperature liquid tetramethylsilane (TMS) as active element are described in detail. As absorber planed carbon steel slabs had been used. The charge yield is 70% of that in a very pure sample of the liquid. A long term stability of the signal with a lifetime of half a year has been realized. Experiences are described and the results explained in detail. (orig.) [de

  10. Pion showers in highly granular calorimeters

    Czech Academy of Sciences Publication Activity Database

    Cvach, Jaroslav

    2012-01-01

    Roč. 79, č. 4 (2012), s. 859-862 ISSN 0304-4289. [International Symposium on Lepton-Photon Interactions at High Energies /25./. Mumbai, 22.08.2011-27.08.2011] R&D Projects: GA MŠk LA09042 Institutional research plan: CEZ:AV0Z10100502 Keywords : International Linear Collider * particle flow algorithm * calorimeter resolution Subject RIV: BF - Elementary Particles and High Energy Physics Impact factor: 0.562, year: 2012

  11. Electron Reconstruction in the CMS Electromagnetic Calorimeter

    CERN Document Server

    Meschi, Emilio; Seez, Christopher; Vikas, Pratibha

    2001-01-01

    This note describes the reconstruction of electrons using the electromagnetic calorimeter (ECAL) alone. This represents the first step in the High Level Trigger reconstruction and selection chain. By making "super-clusters" (i.e. clusters of clusters) much of the energy radiated by bremsstrahlung in the tracker material can be recovered. Representative performance figures for energy and position resolution in the barrel are given.

  12. A no-load RF calorimeter

    Science.gov (United States)

    Chernoff, R. C.

    1975-01-01

    The described device can be used to measure the output of any dc powered RF source. No dummy load is required for the measurements. The device is, therefore, called the 'no-load calorimeter' (NLC). The NLC measures the power actually fed to the antenna or another useful load. It is believed that the NLC can compete successfully with directional coupler type systems in measuring the output of high-power RF sources.

  13. Analytical heat transfer modeling of a new radiation calorimeter

    Energy Technology Data Exchange (ETDEWEB)

    Obame Ndong, Elysée [Department of Industrial Engineering and Maintenance, University of Sciences and Technology of Masuku (USTM), BP 941 Franceville (Gabon); Grenoble Electrical Engineering Laboratory (G2Elab), University Grenoble Alpes and CNRS, G2Elab, F38000 Grenoble (France); Gallot-Lavallée, Olivier [Grenoble Electrical Engineering Laboratory (G2Elab), University Grenoble Alpes and CNRS, G2Elab, F38000 Grenoble (France); Aitken, Frédéric, E-mail: frederic.aitken@g2elab.grenoble-inp.fr [Grenoble Electrical Engineering Laboratory (G2Elab), University Grenoble Alpes and CNRS, G2Elab, F38000 Grenoble (France)

    2016-06-10

    Highlights: • Design of a new calorimeter for measuring heat power loss in electrical components. • The calorimeter can operate in a temperature range from −50 °C to 150 °C. • An analytical model of heat transfers for this new calorimeter is presented. • The theoretical sensibility of the new apparatus is estimated at ±1 mW. - Abstract: This paper deals with an analytical modeling of heat transfers simulating a new radiation calorimeter operating in a temperature range from −50 °C to 150 °C. The aim of this modeling is the evaluation of the feasibility and performance of the calorimeter by assessing the measurement of power losses of some electrical devices by radiation, the influence of the geometry and materials. Finally a theoretical sensibility of the new apparatus is estimated at ±1 mW. From these results the calorimeter has been successfully implemented and patented.

  14. Design, Construction and Commissioning of the Digital Hadron Calorimeter - DHCAL

    CERN Document Server

    Adams, C; Bilki, B.; Butler, J.; Corriveau, F.; Cundiff, T.; Drake, G.; Francis, K.; Furst, B.; Guarino, V.; Haberichter, B.; Hazen, E.; Hoff, J.; Holm, S.; Kreps, A.; DeLurgio, P.; Matijas, Z.; Monte, L.Dal; Mucia, N.; Norbeck, E.; Northacker, D.; Onel, Y.; Pollack, B.; Repond, J.; Schlereth, J.; Skrzecz, F.; Smith, J.R.; Trojand, D.; Underwood, D.; Velasco, M.; Walendziak, J.; Wood, K.; Wu, S.; Xia, L.; Zhang, Q.; Zhao, A.

    2016-01-01

    A novel hadron calorimeter is being developed for future lepton colliding beam detectors. The calorimeter is optimized for the application of Particle Flow Algorithms (PFAs) to the measurement of hadronic jets and features a very finely segmented readout with 1 x 1 cm2 cells. The active media of the calorimeter are Resistive Plate Chambers (RPCs) with a digital, i.e. one-bit, readout. To first order the energy of incident particles in this calorimeter is reconstructed as being proportional to the number of pads with a signal over a given threshold. A large-scale prototype calorimeter with approximately 500,000 readout channels has been built and underwent extensive testing in the Fermilab and CERN test beams. This paper reports on the design, construction, and commissioning of this prototype calorimeter.

  15. Some hadron calorimeter properties relevant to storage rings

    International Nuclear Information System (INIS)

    Corden, M.J.; Dowell, J.D.; Edwards, M.; Ellis, N.; Garvey, J.; Grant, D.; Homer, R.J.; Kenyon, I.R.; McMahon, T.; Schanz, G.; Sumorok, K.C.T.O.; Watkins, P.M.; Wilson, J.A.; Eisenhandler, E.; Gibson, W.R.; Kalmus, P.I.P.; Thompson, G.; Arnison, G.; Astbury, A.; Grayer, G.; Haynes, W.J.; Hill, D.; Nandi, A.K.; Roberts, C.; Shah, T.P.

    1982-01-01

    At wide angles in a storage ring environment, a substantial part of the energy seen by a hadron calorimeter can be in the form of very low momentum particles such as jet fragments or resonance cascade decay products. Data are presented on the deviations from Gaussian resolution and linear response for such low momentum particles. The differing responses to incident e - , μ - , π +- , K +- , p and anti p at momenta below 10 GeV/c are also compared. In addition, the authors discuss the significance of angle effects for a 4π calorimeter, and the problems of combining data from calorimeters with different physical characteristics. Experimental data are presented on the difference in hadron response between a fine grain (electromagnetic) lead calorimeter and a coarser (hadron) iron calorimeter, and on the dependence of the response on the energy sharing between the two calorimeters. (Auth.)

  16. Analytical heat transfer modeling of a new radiation calorimeter

    International Nuclear Information System (INIS)

    Obame Ndong, Elysée; Gallot-Lavallée, Olivier; Aitken, Frédéric

    2016-01-01

    Highlights: • Design of a new calorimeter for measuring heat power loss in electrical components. • The calorimeter can operate in a temperature range from −50 °C to 150 °C. • An analytical model of heat transfers for this new calorimeter is presented. • The theoretical sensibility of the new apparatus is estimated at ±1 mW. - Abstract: This paper deals with an analytical modeling of heat transfers simulating a new radiation calorimeter operating in a temperature range from −50 °C to 150 °C. The aim of this modeling is the evaluation of the feasibility and performance of the calorimeter by assessing the measurement of power losses of some electrical devices by radiation, the influence of the geometry and materials. Finally a theoretical sensibility of the new apparatus is estimated at ±1 mW. From these results the calorimeter has been successfully implemented and patented.

  17. Run 1 Performance of the ATLAS Tile Calorimeter

    CERN Document Server

    Heelan, Louise; The ATLAS collaboration

    2014-01-01

    The ATLAS Tile hadronic calorimeter (TileCal) provides highly-segmented energy measurements of incoming particles. It is a key detector for the measurement of hadrons, jets, tau leptons and missing transverse energy. It is also useful for identification and reconstruction of muons due to good signal to noise ratio. The calorimeter consists of thin steel plates and 460,000 scintillating tiles configured into 5000 cells, each viewed by two photomultipliers. The calorimeter response and its readout electronics is monitored to better than 1% using radioactive source, laser and charge injection systems. The calibration and performance of the calorimeter have been established through test beam measurements, cosmic ray muons and the large sample of proton-proton collisions acquired in 2011 and 2012. Results on the calorimeter performance are presented, including the absolute energy scale, timing, noise and associated stabilities. The results demonstrate that the Tile Calorimeter has performed well within the design ...

  18. A highly-sensitive label-free biosensor based on two dimensional photonic crystals with negative refraction

    Science.gov (United States)

    Malmir, Narges; Fasihi, Kiazand

    2017-11-01

    In this work, we present a novel high-sensitive optical label-free biosensor based on a two-dimensional photonic crystal (2D PC). The suggested structure is composed of a negative refraction structure in a hexagonal lattice PC, along with a positive refraction structure which is arranged in a square lattice PC. The frequency shift of the transmission peak is measured respect to the changes of refractive indices of the studied materials (the blood plasma, water, dry air and normal air). The studied materials are filled into a W1 line-defect waveguide which is located in the PC structure with positive refraction (the microfluidic nanochannel). Our numerical simulations, which are based on finite-difference time-domain (FDTD) method, show that in the proposed structure, a sensitivity about 1100 nm/RIU and a transmission efficiency more than 75% can be achieved. With this design, to the best of our knowledge, the obtained sensitivity and the transmission efficiency are one of the highest values in the reported PC label-free biosensors.

  19. The new ATLAS Fast Calorimeter Simulation

    CERN Document Server

    Hasib, Ahmed; The ATLAS collaboration

    2017-01-01

    Producing the very large samples of simulated events required by many physics and performance studies with the ATLAS detector using the full GEANT4 detector simulation is highly CPU intensive. Fast simulation tools are a useful way of reducing CPU requirements when detailed detector simulations are not needed. During the LHC Run-1, a fast calorimeter simulation (FastCaloSim) was successfully used in ATLAS. FastCaloSim provides a simulation of the particle energy response at the calorimeter read-out cell level, taking into account the detailed particle shower shapes and the correlations between the energy depositions in the various calorimeter layers. It is interfaced to the standard ATLAS digitization and reconstruction software, and it can be tuned to data more easily than GEANT4. Now an improved version of FastCaloSim is in development, incorporating the experience with the version used during Run-1. The new FastCaloSim makes use of statistical techniques such as principal component analysis, and a neural n...

  20. Beam tests of the ZEUS barrel calorimeter

    Energy Technology Data Exchange (ETDEWEB)

    Bernstein, A; Bienz, T; Caldwell, A; Chen, L; Derrick, M; Gialas, I; Hamri, A; Imlay, R; Kartik, S; Kim, H J; Kinnel, T; Kreutzmann, H; Li, C G; Lim, J N; Loveless, R; Lu, B; Mallik, U; McLean, K W; McNeil, R; Metcalf, W; Musgrave, B; Oh, B Y; Park, S; Parsons, J A; Reeder, D; Repond, J; Ritz, S; Roco, M T.P.; Sandler, P H; Sciulli, F; Smith, W H; Talaga, R L; Tzanakos, G; Wai, L; Wang, M Z; Whitmore, J; Wu, J; Yang, S [Argonne National Lab., IL (United States) Columbia Univ., New York, NY (United States) Nevis Labs., Irvington-on-Hudson, NY (United States) Univ. of Iowa, Iowa City, IA (United States) Louisiana State Univ., Baton Rouge, LA (United States) Ohio State Univ., Columbus, OH (United States) Pennsylvania State Univ., University Park, PA (United States) Virginia Polytechnic Inst., and State Univ., Blacksburg, VA (United States) Univ. of Wisconsin, Madison, WI (United States)

    1993-11-15

    A fully compensating uranium-scintillator calorimeter was constructed for the ZEUS detector at HERA. Several of the barrel calorimeter modules were subjected to beam tests at Fermilab before shipping them to DESY for installation. The calibrations of the modules used beams of electrons and hadrons, measuring the uniformity of the response, and checking the resolution. The runs also provided opportunity to test a large fraction of the actual ZEUS calorimeter readout system in an integrated beam environment more than one year before HERA turn on. The experiment utilized two computer controlled mechanical structures, one of which was capable of holding up to four modules in order to study shower containment, and a magnetic spectrometer with a high resolution beam tracking system. During two running periods, beams of 6 to 110 GeV containing e, [mu], [pi], and anti p were used. The results show energy resolutions of 35%/[radical]E for hadrons and 19%/[radical]E for electrons, uniformities at the 1% level, energy nonlinearity less than 1%, and equal response for electrons and hadrons. (orig.)

  1. An absorbed dose calorimeter for IMRT dosimetry

    International Nuclear Information System (INIS)

    Duane, S.; Aldehaybes, M.; Bailey, M.; Lee, N.D.; Thomas, C.G.; Palmans, H.

    2012-01-01

    A new calorimeter for dosimetry in small and complex fields has been built. The device is intended for the direct determination of absorbed dose to water in moderately small fields and in composite fields such as IMRT treatments, and as a transfer instrument calibrated against existing absorbed dose standards in conventional reference conditions. The geometry, materials and mode of operation have been chosen to minimize detector perturbations when used in a water phantom, to give a reasonably isotropic response and to minimize the effects of heat transfer when the calorimeter is used in non-reference conditions in a water phantom. The size of the core is meant to meet the needs of measurement in IMRT treatments and is comparable to the size of the air cavity in a type NE2611 ionization chamber. The calorimeter may also be used for small field dosimetry. Initial measurements in reference conditions and in an IMRT head and neck plan, collapsed to gantry angle zero, have been made to estimate the thermal characteristics of the device, and to assess its performance in use. The standard deviation (estimated repeatability) of the reference absorbed dose measurements was 0.02 Gy (0.6%). (authors)

  2. Upgrading the ATLAS Tile Calorimeter electronics

    CERN Document Server

    Souza, J; The ATLAS collaboration

    2014-01-01

    The Tile Calorimeter (TileCal) is the hadronic calorimeter covering the central region of the ATLAS experiment at LHC. The TileCal readout consists of about 10000 channels. Its main upgrade will occur for the High Luminosity LHC phase (phase 2) where the peak luminosity will increase 5-fold compared to the design luminosity (10exp34 cm−2s−1) but with maintained energy (i.e. 7+7 TeV). An additional increase of the average luminosity with a factor of 2 can be achieved by luminosity leveling. This upgrade will probably happen around 2023. The upgrade aims at replacing the majority of the on- and off-detector electronics so that all calorimeter signals are directly digitized and sent to the off-detector electronics in the counting room. To achieve the required reliability, redundancy has been introduced at different levels. The smallest independent on-detector electronics module has been reduced from 45 channels to 6, greatly reducing the consequences of a failure in the on-detector electronics. The size of t...

  3. Upgrade of the ATLAS Tile Calorimeter

    CERN Document Server

    Reed, Robert; The ATLAS collaboration

    2014-01-01

    The Tile Calorimeter (TileCal) is the main hadronic calorimeter covering the central region of the ATLAS experiment at LHC. TileCal readout consists of about 10000 channels. The bulk of its upgrade will occur for the High Luminosity LHC operation (Phase 2 around 2023) where the peak luminosity will increase 5x compared to the design luminosity (10^{34} cm^{-2}s^{-1}) but with maintained energy (i.e. 7+7 TeV). The TileCal upgrade aims to replace the majority of the on- and off-detector electronics so that all calorimeter signals can be digitized and directly sent to the off-detector electronics in the counting room. This will reduce pile-up problems and allow more complex trigger algorithms. To achieve the required reliability, redundancy has been introduced at different levels. Three different options are presently being investigated for the front-end electronic upgrade. Extensive test beam studies will determine which option will be selected. 10 Gbps optical links are used to read out all digitized data to t...

  4. Upgrading the ATLAS Tile Calorimeter electronics

    CERN Document Server

    Oreglia, M; The ATLAS collaboration

    2013-01-01

    The Tile Calorimeter (TileCal) is the hadronic calorimeter covering the most central region of the ATLAS experiment at LHC. The TileCal readout consists of about 10000 channels. The main upgrade will occur for the High Luminosity LHC phase (phase 2) which is scheduled around 2022. The upgrade aims at replacing the majority of the on- and off- detector electronics so that all calorimeter signals are directly digitized and sent to the off-detector electronics in the counting room. An ambitious upgrade development program is pursued studying different electronics options. Three different options are presently being investigated for the front-end electronic upgrade. Which one to use will be decided after extensive test beam studies. High speed optical links are used to read out all digitized data to the counting room. For the off-detector electronics a new back-end architecture is being developed, including the initial trigger processing and pipeline memories. A demonstrator prototype read-out for a slice of the ...

  5. Upgrade of the ATLAS Tile Calorimeter Electronics

    CERN Document Server

    Moreno, P; The ATLAS collaboration

    2014-01-01

    The Tile Calorimeter (TileCal) is the hadronic calorimeter covering the central region of the ATLAS experiment at LHC. The TileCal readout consists of about 10000 channels. The bulk of its upgrade will occur for the High Luminosity LHC phase (phase 2) where the peak luminosity will increase 5x compared to the design luminosity (10^34 cm−2s−1) but with maintained energy (i.e. 7+7 TeV). An additional increase of the average luminosity with a factor of 2 can be achieved by luminosity leveling. This upgrade is expected to happen around 2023. The TileCal upgrade aims at replacing the majority of the on- and off-detector electronics to the extent that all calorimeter signals will be digitized and sent to the off-detector electronics in the counting room. To achieve the required reliability, redundancy has been introduced at different levels. Three different options are presently being investigated for the front-end electronic upgrade. Extensive test beam studies will determine which option will be selected. 10 ...

  6. Upgrade of the ATLAS Tile Calorimeter

    CERN Document Server

    Moreno, P; The ATLAS collaboration

    2016-01-01

    The Tile Calorimeter (TileCal) is the central hadronic calorimeter covering the central region of the ATLAS experiment at LHC. The TileCal readout consists of about 10000 channels. The bulk of its upgrade will occur for the High Luminosity LHC phase (Phase 2) where the peak luminosity will increase 5$\\times$ compared to the design luminosity ($10^{34} cm^{-2}s^{-1}$) but with maintained energy (i.e. 7+7 TeV). The TileCal upgrade aims at replacing the majority of the on- and off-detector electronics to the extent that all calorimeter signals will be digitized and sent to the off-detector electronics in the counting room. To achieve the required reliability, redundancy has been introduced at different levels. Three different options are presently being investigated for the front-end electronic upgrade. Extensive test beam studies will determine which option will be selected. 10 Gbps optical links are used to read out all digitized data to the counting room while 5 Gbps down-links are used for synchronization, c...

  7. Upgrade of the ATLAS Tile Calorimeter Electronics

    CERN Document Server

    Carrio, F

    2015-01-01

    The Tile Calorimeter (TileCal) is the hadronic calorimeter covering the central region of the ATLAS experiment at LHC. The TileCal readout consists of about 10000 channels. The bulk of its upgrade will occur for the High Luminosity LHC phase (P hase - II ) where the pea k luminosity will increase 5 times compared to the design luminosity (10 34 cm −2 s −1 ) but with maintained energy (i.e. 7+7 TeV). An additional increase of the average luminosity with a factor of 2 can be achieved by luminosity levelling. This upgrade is expe cted to happen around 202 4 . The TileCal upgrade aims at replacing the majority of the on - and off - detector electronics to the extent that all calorimeter signals will be digitized and sent to the off - detector electronics in the counting room. To achieve th e required reliability, redundancy has been introduced at different levels. Three different options are presently being investiga...

  8. Upgrading the ATLAS Tile Calorimeter electronics

    CERN Document Server

    Carrio, F; The ATLAS collaboration

    2013-01-01

    The Tile Calorimeter (TileCal) is the hadronic calorimeter covering the most central region of the ATLAS experiment at LHC. The TileCal readout consists of about 10000 channels. Its main upgrade will occur for the High Luminosity LHC phase (phase 2) where the luminosity will have increased 5-fold compared to the design luminosity (1034 cm−2s−1) but with maintained energy (i.e. 7+7 TeV). An additional luminosity increase by a factor of 2 can be achieved by luminosity leveling. This upgrade will probably happen around 2022. The upgrade aims at replacing the majority of the on- and off- detector electronics so that all calorimeter signals are directly digitized and sent to the off-detector electronics in the counting room. To achieve the required reliability, redundancy has been introduced at different levels. An ambitious upgrade development program is pursued studying different electronics options. Three different options are presently being investigated for the front-end electronic upgrade. Which one to u...

  9. The New ATLAS Fast Calorimeter Simulation

    CERN Document Server

    Heath, Matthew Peter; The ATLAS collaboration

    2017-01-01

    Producing the large samples of simulated events required by many physics and performance studies with the ATLAS detector using the full GEANT4 detector simulation is highly CPU intensive. Fast simulation tools are a useful way of reducing the CPU requirements when detailed detector simulations are not needed. During Run-1 of the LHC, a fast calorimeter simulation (FastCaloSim) was successfully used in ATLAS. FastCaloSim provides a simulation of the particle energy response at the calorimeter read-out cell level, taking into account the detailed particle shower shapes and the correlations between the energy depositions in the various calorimeter layers. It is interfaced to the standard ATLAS digitisation and reconstruction software, and it can be tuned to data more easily than Geant4. Now an improved version of FastCaloSim is in development, incorporating the experience with the version used during Run-1. The new FastCaloSim aims to overcome some limitations of the first version by improving the description of...

  10. Fast shower simulation in the ATLAS calorimeter

    International Nuclear Information System (INIS)

    Barberio, E; Boudreau, J; Mueller, J; Tsulaia, V; Butler, B; Young, C C; Cheung, S L; Savard, P; Dell'Acqua, A; Simone, A D; Gallas, M V; Ehrenfeld, W; Glazov, A; Placakyte, R; Marshall, Z; Rimoldi, A; Waugh, A

    2008-01-01

    The time to simulate pp collisions in the ATLAS detector is largely dominated by the showering of electromagnetic particles in the heavy parts of the detector, especially the electromagnetic barrel and endcap calorimeters. Two procedures have been developed to accelerate the processing time of electromagnetic particles in these regions: (1) a fast shower parameterisation and (2) a frozen shower library. Both work by generating the response of the calorimeter to electrons and positrons with Geant 4, and then reintroduce the response into the simulation at runtime. In the fast shower parameterisation technique, a parameterisation is tuned to single electrons and used later by simulation. In the frozen shower technique, actual showers from low-energy particles are used in the simulation. Full Geant 4 simulation is used to develop showers down to ∼ 1GeV, at which point the shower is terminated by substituting a frozen shower. Judicious use of both techniques over the entire electromagnetic portion of the ATLAS calorimeter produces an important improvement of CPU time. We discuss the algorithms and their performance in this paper

  11. Performance of the ATLAS Tile calorimeter

    CERN Document Server

    Bertoli, Gabriele; The ATLAS collaboration

    2015-01-01

    The Tile Calorimeter (TileCal) of the ATLAS experiment at the LHC is the central hadronic calorimeter designed for energy reconstruction of hadrons, jets, tau­particles and missing transverse energy. TileCal is a scintillator­steel sampling calorimeter and it covers the region of pseudorapidity < 1.7. The scintillation light produced in the tiles is transmitted by wavelength shifting fibers to photomultiplier tubes (PMTs). The analog signals from the PMTs are amplified, shaped and digitized by sampling the signal every 25 ns. The TileCal front­end electronics read out the signals produced by about 10000 channels measuring energies ranging from ~30 MeV to ~2 TeV. The read­out system is responsible for reconstructing the data in real­time. The digitized signals are reconstructed with the Optimal Filtering algorithm, which computes for each channel the signal amplitude, time and quality factor at the required high rate. Each stage of the signal production from scintillation light to the signal reconstruc...

  12. First Half Of CMS Hadron Calorimeter Completed

    CERN Multimedia

    2001-01-01

    CMS HCAL electronics coordinator John Elias from Fermilab inspecting the assembled first half of the calorimeter. The first half barrel of the CMS hadron calorimeter was completed last month and assembly work on the elements of the second half commenced just last week. This is not a simple task considering the fact that the constructed half-barrel consists of eighteen 30 tonne segments each made with 0.15 mm tolerance. But through the work of everyone on the CMS hadron calorimeter team it is all moving forward. In the LHC, detection of particles produced in collisions of two proton beams requires measurement of their energy. To do this, the particle energy has to be changed into a form that can be easily measured. This is achieved by stopping the initial particles in a dense medium, where they create a shower of secondary particles. While particles that interact through electromagnetic forces (electrons and positrons) create relatively small showers, the size of showers created by hadrons, particles that i...

  13. A continuous flow microfluidic calorimeter: 3-D numerical modeling with aqueous reactants

    Energy Technology Data Exchange (ETDEWEB)

    Sen, Mehmet A., E-mail: mehmet.sen@mathworks.com [Northeastern University, Department of Mechanical and Industrial Engineering, 360 Hungtington Avenue, 334 Snell Engineering Center, Boston, MA 02115 (United States); Kowalski, Gregory J., E-mail: gkowal@coe.neu.edu [Northeastern University, Department of Mechanical and Industrial Engineering, 360 Hungtington Avenue, 334 Snell Engineering Center, Boston, MA 02115 (United States); Fiering, Jason, E-mail: jfiering@draper.com [Charles Stark Draper Laboratory, 555 Technology Square, Cambridge, MA 02139 (United States); Larson, Dale, E-mail: dlarson@draper.com [Charles Stark Draper Laboratory, 555 Technology Square, Cambridge, MA 02139 (United States)

    2015-03-10

    Highlights: • A co-flow microreactor is modeled in flow, reaction/diffusion, and thermal domains. • Analysis shows how arrayed temperature sensors can provide enthalpy of reaction. • Optical plasmonic temperature sensors could be arrayed suitably for calorimetry. • The reactor studied has a volume of 25 nL. - Abstract: A computational analysis of the reacting flow field, species diffusion and heat transfer processes with thermal boundary layer effects in a microchannel reactor with a coflow configuration was performed. Two parallel adjacent streams of aqueous reactants flow along a wide, shallow, enclosed channel in contact with a substrate, which is affixed to a temperature controlled plate. The Fluent computational fluid dynamics package solved the Navier–Stokes, mass transport and energy equations. The energy model, including the enthalpy of reaction as a nonuniform heat source, was validated by calculating the energy balance at several control volumes in the microchannel. Analysis reveals that the temperature is nearly uniform across the channel thickness, in the direction normal to the substrate surface; hence, measurements made by sensors at or near the surface are representative of the average temperature. Additionally, modeling the channel with a glass substrate and a silicone cover shows that heat transfer is predominantly due to the glass substrate. Finally, using the numerical results, we suggest that a microcalorimeter could be based on this configuration, and that temperature sensors such as optical nanohole array sensors could have sufficient spatial resolution to determine enthalpy of reaction.

  14. A continuous flow microfluidic calorimeter: 3-D numerical modeling with aqueous reactants

    International Nuclear Information System (INIS)

    Sen, Mehmet A.; Kowalski, Gregory J.; Fiering, Jason; Larson, Dale

    2015-01-01

    Highlights: • A co-flow microreactor is modeled in flow, reaction/diffusion, and thermal domains. • Analysis shows how arrayed temperature sensors can provide enthalpy of reaction. • Optical plasmonic temperature sensors could be arrayed suitably for calorimetry. • The reactor studied has a volume of 25 nL. - Abstract: A computational analysis of the reacting flow field, species diffusion and heat transfer processes with thermal boundary layer effects in a microchannel reactor with a coflow configuration was performed. Two parallel adjacent streams of aqueous reactants flow along a wide, shallow, enclosed channel in contact with a substrate, which is affixed to a temperature controlled plate. The Fluent computational fluid dynamics package solved the Navier–Stokes, mass transport and energy equations. The energy model, including the enthalpy of reaction as a nonuniform heat source, was validated by calculating the energy balance at several control volumes in the microchannel. Analysis reveals that the temperature is nearly uniform across the channel thickness, in the direction normal to the substrate surface; hence, measurements made by sensors at or near the surface are representative of the average temperature. Additionally, modeling the channel with a glass substrate and a silicone cover shows that heat transfer is predominantly due to the glass substrate. Finally, using the numerical results, we suggest that a microcalorimeter could be based on this configuration, and that temperature sensors such as optical nanohole array sensors could have sufficient spatial resolution to determine enthalpy of reaction

  15. Performance of the upgraded small angle tile calorimeter at LEP

    CERN Document Server

    Alvsvaag, S J; Barreira, G; Benvenuti, Alberto C; Bigi, M; Bonesini, M; Bozzo, M; Camporesi, T; Carling, H; Cassio, V; Castellani, L; Cereseto, R; Chignoli, F; Della Ricca, G; Dharmasiri, D R; Espirito-Santo, M C; Falk, E; Fenyuk, A; Ferrari, P; Gamba, D; Giordano, V; Guz, Yu; Guerzoni, M; Gumenyuk, S A; Hedberg, V; Jarlskog, G; Karyukhin, A N; Klovning, A; Konoplyannikov, A K; Kronkvist, I J; Lanceri, L; Leoni, R; Maeland, O A; Maio, A; Mazza, R; Migliore, E; Navarria, Francesco Luigi; Nossum, B; Obraztsov, V F; Onofre, A; Paganoni, M; Pegoraro, M; Peralta, L; Petrovykh, L P; Pimenta, M; Poropat, P; Prest, M; Read, A L; Romero, A; Shalanda, N A; Simonetti, L; Skaali, T B; Stugu, B; Terranova, F; Tomé, B; Torassa, E; Trapani, P P; Verardi, M G; Vallazza, E; Vlasov, E; Zaitsev, A

    1998-01-01

    The small angle tile calorimeter (STIC) provides calorimetric coverage in the very forward region of the DELPHI experiment at the CERN LEP collider. The structure of the calorimeters, built with so- called "shashlik" technique, $9 allows the insertion of tracking detectors within the sampling structure, in order to make it possible to determine the direction of the showering particle. Presented here are some results demonstrating the performance of the $9 calorimeter and of these tracking detectors at LEP. (5 refs).

  16. Design and construction of the ZEUS barrel calorimeter

    International Nuclear Information System (INIS)

    Repond, J.

    1990-01-01

    The mechanical design and construction techniques of the barrel calorimeter for the ZEUS detector are presented. The calorimeter uses alternate layers of depleted uranium and scintillator with one radiation length sampling. The unit cell has e/h = 1 which yields an optimal energy resolution for hadronic jets. We discuss the placing of the structural components and cracks between modules. Details of the construction and assembly effort needed to realize the total calorimeter are reported. 4 figs., 1 tab

  17. Microfluidic stretchable RF electronics.

    Science.gov (United States)

    Cheng, Shi; Wu, Zhigang

    2010-12-07

    Stretchable electronics is a revolutionary technology that will potentially create a world of radically different electronic devices and systems that open up an entirely new spectrum of possibilities. This article proposes a microfluidic based solution for stretchable radio frequency (RF) electronics, using hybrid integration of active circuits assembled on flex foils and liquid alloy passive structures embedded in elastic substrates, e.g. polydimethylsiloxane (PDMS). This concept was employed to implement a 900 MHz stretchable RF radiation sensor, consisting of a large area elastic antenna and a cluster of conventional rigid components for RF power detection. The integrated radiation sensor except the power supply was fully embedded in a thin elastomeric substrate. Good electrical performance of the standalone stretchable antenna as well as the RF power detection sub-module was verified by experiments. The sensor successfully detected the RF radiation over 5 m distance in the system demonstration. Experiments on two-dimensional (2D) stretching up to 15%, folding and twisting of the demonstrated sensor were also carried out. Despite the integrated device was severely deformed, no failure in RF radiation sensing was observed in the tests. This technique illuminates a promising route of realizing stretchable and foldable large area integrated RF electronics that are of great interest to a variety of applications like wearable computing, health monitoring, medical diagnostics, and curvilinear electronics.

  18. Development of an Extraterrestrial Organic Analyzer (EOA) for Highly Sensitive Organic Detection on an Ice Shell Impact Penetrator (IceShIP)

    Science.gov (United States)

    Stockton, A. M.; Duca, Z. A.; Cato, M.; Cantrell, T.; Kim, J.; Putman, P.; Schmidt, B. E.

    2016-12-01

    Kinetic penetrators have the potential to enable low cost in situ measurements of the ice of worlds including Europa and Enceladus [1]. Their small size and mass, critical to limiting their kinetic energy, makes them ideal small landers riding on primarily orbiter missions, while enabling sampling at several m depth due to burial and excavation. In situ microfluidic-based organic analysis systems are a powerful, miniaturized approach for detecting markers of habitability and recent biological activity. Development of microfluidic technology, like that of the Mars Organic Analyzer (MOA) [2,3] and Enceladus Organic Analyzer (EOA), has led to an instrument capable of in situ organic chemical analysis compatible with a kinetic penetrator platform. This technology uses an integrated microfluidic processor to prepare samples for analysis via fluorescent derivatization prior to highly sensitive laser-induced fluorescence (LIF) detection. Selective derivatization in the presence of a chiral selector enables distinction between amino acid enantiomers. Finite element analysis of the core microfluidic processing and analytical device indicated that the device itself is more than capable of surviving the stresses associated with an impact acceleration of >50,000g. However, a number of developments were still required to enable a flight-ready system. Preliminary experiments indicated that moving from a pneumatically-actuated to a hydraulically-actuated microvalve system may provide better impact resistance. A hydraulically-actuated microvalve system was developed and tested. A modification of an established microfabricated LIF detection system would use indium bump bonding to permanently weld optical components using standard microfabrication techniques with perfect alignment. Recent work has also focused on developing and characterizing impact-resistant electronics. This work shows the low-TRL development of EOA's LIF and microfluidic subsystems for future planetary impact

  19. Performance of the SLD Warm Iron Calorimeter prototype

    International Nuclear Information System (INIS)

    Callegari, G.; Piemontese, L.; De Sangro, R.; Peruzzi, I.; Piccolo, M.; Busza, W.; Friedman, J.; Johnson, A.; Kendall, H.; Kistiakowsky, V.

    1986-03-01

    A prototype hadron calorimeter, of similar design to the Warm Iron Calorimeter (WIC) planned for the SLD experiment, has been built and its performance has been studied in a test beam. The WIC is an iron sampling calorimeter whose active elements are plastic streamer tubes similar to those used for the Mont-Blanc proton decay experiment. The construction and operation of the tubes will be briefly described together with their use in an iron calorimeter - muon tracker. Efficiency, resolution and linearity have been measured in a hadron/muon beam up to 11 GeV. The measured values correspond to the SLD design goals

  20. Calorimeters for diagnosis of laser-fusion experiments

    International Nuclear Information System (INIS)

    Gunn, S.R.

    1976-01-01

    A variety of calorimeters have been developed for measuring ions, x-rays, and scattered radiation emanating from laser-pulse-imploded fusion targets. The ion and x-ray calorimeters use metal or glass absorbers to reflect or transmit most of the scattered laser radiation; the versions using metal absorbers also incorporate a differential construction to compensate for the fraction of the scattered laser radiation that is absorbed. The scattered-radiation calorimeters use colored glass to absorb the radiation and a transparent glass shield to remove ions and x rays. Most of the calorimeters use commercial semiconductor thermoelectric modules as the temperature sensors

  1. The ATLAS liquid argon calorimeter--status and expected performance

    International Nuclear Information System (INIS)

    Schacht, Peter

    2004-01-01

    For the ATLAS detector at the LHC, the liquid argon technique is exploited for the electromagnetic calorimetry in the central part and for the electromagnetic and hadronic calorimetry in the forward and backward regions. The construction of the calorimeter is well advanced with full cold tests of the barrel calorimeter and first endcap calorimeter only months away. The status of the project is discussed as well as the related results from beam test studies of the various calorimeter subdetectors. The results show that the expected performance meets the ATLAS requirements as specified in the ATLAS Technical Design Report

  2. Spontaneous oscillations in microfluidic networks

    Science.gov (United States)

    Case, Daniel; Angilella, Jean-Regis; Motter, Adilson

    2017-11-01

    Precisely controlling flows within microfluidic systems is often difficult which typically results in systems being heavily reliant on numerous external pumps and computers. Here, I present a simple microfluidic network that exhibits flow rate switching, bistablity, and spontaneous oscillations controlled by a single pressure. That is, by solely changing the driving pressure, it is possible to switch between an oscillating and steady flow state. Such functionality does not rely on external hardware and may even serve as an on-chip memory or timing mechanism. I use an analytic model and rigorous fluid dynamics simulations to show these results.

  3. Microfluidic device for drug delivery

    Science.gov (United States)

    Beebe, David J. (Inventor); MacDonald, Michael J. (Inventor); Eddington, David T. (Inventor); Mensing, Glennys A. (Inventor)

    2010-01-01

    A microfluidic device is provided for delivering a drug to an individual. The microfluidic device includes a body that defines a reservoir for receiving the drug therein. A valve interconnects the reservoir to an output needle that is insertable into the skin of an individual. A pressure source urges the drug from the reservoir toward the needle. The valve is movable between a closed position preventing the flow of the drug from the reservoir to the output needle and an open position allowing for the flow of the drug from the reservoir to the output needle in response to a predetermined condition in the physiological fluids of the individual.

  4. Bridging Flows: Microfluidic End‐User Solutions

    DEFF Research Database (Denmark)

    Sabourin, David

    Microfluidic applications hold promise for many different end‐users both within and outside, and across many different research communities. Despite the benefits of microfluidic approaches, adoption and implementation thereof is often hindered by practical issues. Microfluidic components which......‐integrated interconnection and miniaturized peristaltic pump solutions were then combined into modular microfluidic systems. One system provides high interconnection numbers/density and allows many possible configurations. Additionally, and apart from many other accounts of modular microfluidic solutions, methods...... for control and actuation of microfluidic networks built from the modular components is described. Prototypes of the microfluidic system have begun to be distributed to external collaborators and researcher parties. These end‐users will assist in the validation of the approach and ultimately fulfil the key...

  5. Dual-nozzle microfluidic droplet generator

    Science.gov (United States)

    Choi, Ji Wook; Lee, Jong Min; Kim, Tae Hyun; Ha, Jang Ho; Ahrberg, Christian D.; Chung, Bong Geun

    2018-05-01

    The droplet-generating microfluidics has become an important technique for a variety of applications ranging from single cell analysis to nanoparticle synthesis. Although there are a large number of methods for generating and experimenting with droplets on microfluidic devices, the dispensing of droplets from these microfluidic devices is a challenge due to aggregation and merging of droplets at the interface of microfluidic devices. Here, we present a microfluidic dual-nozzle device for the generation and dispensing of uniform-sized droplets. The first nozzle of the microfluidic device is used for the generation of the droplets, while the second nozzle can accelerate the droplets and increase the spacing between them, allowing for facile dispensing of droplets. Computational fluid dynamic simulations were conducted to optimize the design parameters of the microfluidic device.

  6. R&D Studies of the ATLAS LAr Calorimeter Readout Electronics for super-LHC

    CERN Document Server

    Chen, H

    2009-01-01

    The ATLAS Liquid Argon (LAr) calorimeters are high precision, high sensitivity and high granularity detectors designed to provide precision measurements of electrons, photons, jets and missing transverse energy. 180,000 signals are digitized and processed real-time on detector, to provide energy and time deposited in each detector element at every occurrence of the L1-trigger. A luminosity upgrade (x10) of the LHC will occur around 2016. The current readout electronics will have to be upgraded to sustain the higher radiation levels. A completely innovative readout scheme is being developed. The frontend readout will send out data continuously at each bunch crossing through highspeed radiation resistant optical links. The data (100Gbps each board) will be processed real-time with the possibility of implementing trigger algorithms for clusters and electron/photon identification at a much higher granularity than what currently implemented. We present here an overview of the R&D activities and architectural s...

  7. In-line microfluidic refractometer based on C-shaped fiber assisted photonic crystal fiber Sagnac interferometer.

    Science.gov (United States)

    Wu, Chuang; Tse, Ming-Leung Vincent; Liu, Zhengyong; Guan, Bai-Ou; Lu, Chao; Tam, Hwa-Yaw

    2013-09-01

    We propose and demonstrate a highly sensitive in-line photonic crystal fiber (PCF) microfluidic refractometer. Ultrathin C-shaped fibers are spliced in-between the PCF and standard single-mode fibers. The C-shaped fibers provide openings for liquid to flow in and out of the PCF. Based on a Sagnac interferometer, the refractive index (RI) response of the device is investigated theoretically and experimentally. A high sensitivity of 6621 nm/RIU for liquid RI from 1.330 to 1.333 is achieved in the experiment, which agrees well with the theoretical analysis.

  8. Microfluidic biosensor for β-Hydroxybutyrate (βHBA) determination of subclinical ketosis diagnosis.

    Science.gov (United States)

    Weng, Xuan; Zhao, Wenting; Neethirajan, Suresh; Duffield, Todd

    2015-02-12

    Determination of β-hydroxybutyrate (βHBA) is a gold standard for diagnosis of Subclinical Ketosis (SCK), a common disease in dairy cows that causes significant economic loss. Early detection of SCK can help reduce the risk of the disease progressing into clinical stage, thus minimizing economic losses on dairy cattle. Conventional laboratory methods are time consuming and labor-intensive, requiring expensive and bulky equipment. Development of portable and robust devices for rapid on-site SCK diagnosis is an effective way to prevent and control ketosis and can significantly aid in the management of dairy animal health. Microfluidic technology provides a rapid, cost-effective way to develop handheld devices for on-farm detection of sub-clinical ketosis. In this study, a highly sensitive microfluidics-based biosensor for on-site SCK diagnosis has been developed. A rapid, low-cost microfluidic biosensor with high sensitivity and specificity was developed for SCK diagnosis. Determination of βHBA was employed as the indicator in the diagnosis of SCK. On-chip detection using miniaturized and cost-effective optical sensor can be finished in 1 minute with a detection limit of 0.05 mM concentration. Developed microfluidic biosensor was successfully tested with the serum samples from dairy cows affected by SCK. The results of the developed biosensor agreed well with two other laboratory methods. The biosensor was characterized by high sensitivity and specificity towards βHBA with a detection limit of 0.05 mM. The developed microfluidic biosensor provides a promising prototype for a cost-effective handheld meter for on-site SCK diagnosis. By using microfluidic method, the detection time is significantly decreased compared to other laboratory methods. Here, we demonstrate a field-deployable device to precisely identify and measure subclinical ketosis by specific labeling and quantification of β-hydroxybutyate in cow blood samples. A real-time on-site detection system will

  9. The uranium liquid argon calorimeter of the D0 experiment: Experience in realizing a large system

    International Nuclear Information System (INIS)

    Guryn, W.

    1991-01-01

    The major aspects in realizing the calorimeter system of the D OE experiment are discussed. They include: technologies developed for calorimeter production, schedule, and experience with module production

  10. Integrated microfluidic probe station.

    Science.gov (United States)

    Perrault, C M; Qasaimeh, M A; Brastaviceanu, T; Anderson, K; Kabakibo, Y; Juncker, D

    2010-11-01

    The microfluidic probe (MFP) consists of a flat, blunt tip with two apertures for the injection and reaspiration of a microjet into a solution--thus hydrodynamically confining the microjet--and is operated atop an inverted microscope that enables live imaging. By scanning across a surface, the microjet can be used for surface processing with the capability of both depositing and removing material; as it operates under immersed conditions, sensitive biological materials and living cells can be processed. During scanning, the MFP is kept immobile and centered over the objective of the inverted microscope, a few micrometers above a substrate that is displaced by moving the microscope stage and that is flushed continuously with the microjet. For consistent and reproducible surface processing, the gap between the MFP and the substrate, the MFP's alignment, the scanning speed, the injection and aspiration flow rates, and the image capture need all to be controlled and synchronized. Here, we present an automated MFP station that integrates all of these functionalities and automates the key operational parameters. A custom software program is used to control an independent motorized Z stage for adjusting the gap, a motorized microscope stage for scanning the substrate, up to 16 syringe pumps for injecting and aspirating fluids, and an inverted fluorescence microscope equipped with a charge-coupled device camera. The parallelism between the MFP and the substrate is adjusted using manual goniometer at the beginning of the experiment. The alignment of the injection and aspiration apertures along the scanning axis is performed using a newly designed MFP screw holder. We illustrate the integrated MFP station by the programmed, automated patterning of fluorescently labeled biotin on a streptavidin-coated surface.

  11. Calibration of Tilecal hadronic calorimeter of the ATLAS

    International Nuclear Information System (INIS)

    Batkova, L.

    2009-01-01

    The aim of a precise calibration of a calorimeter is to get the best response relationship between the calorimeter and the energy of incident particles. Different types of particles interact through various types of interactions with the environment. Therefore, calorimeters are optimized to detect one type of particle (electromagnetic particles and hadrons). Within current high energy physics experiments, where the detectors reached gigantic proportions, calorimeters hold two important features: - serve to measure power showers by complete absorption method; - reconstruct a direction of showers of particles after their interaction with the environment of calorimeter. To deterioration of the resolving power of the hadronic calorimeter contributes incompensation of its response to hadrons and electromagnetic particles (e, μ). They record more energy from electrons as from pions of the same nominal power. During building of experiment of the ATLAS the prototypes of Tile calorimeter were calibrated using Cs and then were tested by means of calibration particle beams (e, μ, π). The work is aimed to evaluation of the response of the muon beam calibration experiment ATLAS. The scope of the work is to determine correction factors for the calibration constants obtained from the primary calibration of the calorimeter by cesium for end Tilecal calorimeter modules. Tile calorimeter modules consist of three layers A, BC and D. A correction factor for calibration constant for A layer was determined by electron beam firing angle less than 20 grad. Muons are used to determine correction factors for the remaining two layers of the end calorimeter module, where the electrons of given energy do not penetrate. (author)

  12. Topology optimization of microfluidic mixers

    DEFF Research Database (Denmark)

    Andreasen, Casper Schousboe; Gersborg, Allan Roulund; Sigmund, Ole

    2009-01-01

    This paper demonstrates the application of the topology optimization method as a general and systematic approach for microfluidic mixer design. The mixing process is modeled as convection dominated transport in low Reynolds number incompressible flow. The mixer performance is maximized by altering...

  13. A microfluidic device with pillars

    DEFF Research Database (Denmark)

    2014-01-01

    The invention provides a microfluidic device for mixing liquid reagents, the device comprises, a chip forming at least one reaction chamber between a bottom and a top and extending between an inlet and an outlet. To enable manufacturing from less rigid materials, the device comprises pillars...

  14. Microfluidic technology for PET radiochemistry

    International Nuclear Information System (INIS)

    Gillies, J.M.; Prenant, C.; Chimon, G.N.; Smethurst, G.J.; Dekker, B.A.; Zweit, J.

    2006-01-01

    This paper describes the first application of a microfabricated reaction system to positron emission tomography (PET) radiochemistry. We have applied microfluidic technology to synthesise PET radiopharmaceuticals using 18 F and 124 I as labels for fluorodeoxyglucose (FDG) and Annexin-V, respectively. These reactions involved established methods of nucleophilic substitution on a mannose triflate precursor and direct iodination of the protein using iodogen as an oxidant. This has demonstrated a proof of principle of using microfluidic technology to radiochemical reactions involving low and high molecular weight compounds. Using microfluidic reactions, [ 18 F]FDG was synthesised with a 50% incorporation of the available F-18 radioactivity in a very short time of 4 s. The radiolabelling efficiency of 124 I Annexin-V was 40% after 1 min reaction time. Chromatographic analysis showed that such reaction yields are comparable to conventional methods, but in a much shorter time. The yields can be further improved with more optimisation of the microfluidic device itself and its fluid mixing profiles. This demonstrates the potential for this technology to have an impact on rapid and simpler radiopharmaceutical synthesis using short and medium half-life radionuclides

  15. Microfluidic Liquid-Liquid Contactors

    Energy Technology Data Exchange (ETDEWEB)

    Mcculloch, Quinn [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-07-25

    This report describes progress made on the microfluidic contactor. A model was developed to predict its failure, a surrogate chemical system was selected to demonstrate mass transfer, and an all-optical system has been invented and implemented to monitor carryover and flowrates.

  16. Microfluidic devices for biological applications

    CSIR Research Space (South Africa)

    Potgieter, S

    2010-01-01

    Full Text Available Microfluidics is a multi-disciplinary field that deals with the behaviour, control and manipulation of fluids constrained to sub-millilitre volumes. It is proving to be a useful tool for biological studies, affording advantages such as reduced cost...

  17. Mixing in a Microfluid Device

    DEFF Research Database (Denmark)

    Hjorth, Poul G.; Deryabin, Mikhail

    Mixing of fluids in microchannels cannot rely on turbulence since the flow takes place at extremly low Reynolds numbers. Various active and passive devices have been developed to induce mixing in microfluid flow devices. We describe here a model of an active mixer where a transverse periodic flow...

  18. A hidden bias in a common calorimeter calibration scheme

    International Nuclear Information System (INIS)

    Lincoln, Don; Morrow, Greg; Kasper, Peter

    1994-01-01

    In this paper, a common calorimeter calibration scheme is explored and a hidden bias found. Since this bias mimics a non-linearity in response in the calorimeter, it must be understood and removed from the calibration before true non-linearities are investigated. The effect and its removal are explored and understood through straightforward calculus and algebra. ((orig.))

  19. Study of characteristics of gamma-irradiated materials for calorimeters

    International Nuclear Information System (INIS)

    Britvich, G.I.; Vasil'chenko, V.G.; Peresypkin, A.I.

    1992-01-01

    The radiation resistance of some structural materials proposed for use in electromagnetic calorimeters is studied. Particular attention is given to the spectral, dose, and other postradiation characteristics of pure heavy fluorides and their solid solutions: The promise of the use of CdF 2 and CdI 2 crystals in calorimeters is noted. 19 refs., 5 figs

  20. Moving one of the ATLAS end-cap calorimeters

    CERN Multimedia

    Claudia Marcelloni

    2007-01-01

    One of the end-cap calorimeters for the ATLAS experiment is moved using a set of rails. This calorimeter will measure the energy of particles that are produced close to the axis of the beam when two protons collide. It is kept cool inside a cryostat to allow the detector to work at maximum efficiency.

  1. ATLAS Tile Calorimeter central barrel assembly and installation.

    CERN Multimedia

    nikolai topilin

    2009-01-01

    These photos belong to the self-published book by Nikolai Topilin "ATLAS Hadron Calorimeter Assembly". The book is a collection of souvenirs from the years of assembly and installation of the Tile Hadron Calorimeter, which extended from November 2002 until May 2006.

  2. First experimental tests of a lead glass drift calorimeter

    International Nuclear Information System (INIS)

    Guerra, A.D.; Bellazzini, R.; Conti, M.; Massai, M.M.; Schwartz, G.; Habel, R.; Mulera, T.; Perez-Mendez, V.

    1985-10-01

    We are building a drift collection calorimeter, which has a combined radiator and electric field shaping structure made of fused lead glass tubing, treated in a H 2 reducing atmosphere. We describe the construction detail of the calorimeter and the experimental measurements on several prototypes with radioative sources and minimum ionizing particles. 9 refs., 11 figs

  3. Calibration of film dosimeters by means of absorbed dose calorimeters

    International Nuclear Information System (INIS)

    Nikolaev, S.M.; Vanyushkin, B.M.; Kon'kov, N.G.

    1980-01-01

    Methods of graduating film dosimeters by means of calorimeters of absorbed doses, are considered. Graduating of film dosimeters at the energies of accelerated electrons from 4 to 10 MeV can be carried out by means of quasiadiabatic calorimeter of local absorption, the absorber thickness of which should not exceed 5-10% of Rsub(e) value, where Rsub(e) - free electron path of the given energy. In this case film is located inside the calorimeter. For graduating films with thickness not less than (0.1-0.2)Rsub(e) it is suggested to use calorimeter of full absorption; then the graduated dosimeters are located in front of the calorimeter. Graduation of films at small energies of electrons is exercised by means of a package of films, approximately Rsub(e) thick. A design of quasiadiabatic calorimeter, intended for graduating dosimeters within the energy range of electron beam from 4 to 10 MeV, is considered. The quasiadiabatic calorimeter is a thin graphite tablet with heater and thermocouple, surrounded by foam plastic thermostating case. Electricity quantity, accumulated during the radiation field pass, is measured in the case of using the quasiadiabatic calorimeter for film graduating. The results of graduating film dosimeters, obtained using film package with Rsub(e) thickness, are presented. The obtained results coincide within 5% limits with the data known beforehand [ru

  4. The ATLAS Liquid Argon Calorimeter: Construction, Integration, Commissioning

    International Nuclear Information System (INIS)

    Aleksa, Martin

    2006-01-01

    The ATLAS liquid argon (LAr) calorimeter system consists of an electromagnetic barrel calorimeter and two end caps with electromagnetic, hadronic and forward calorimeters. The liquid argon sampling technique, with an accordion geometry was chosen for the barrel electromagnetic calorimeter (EMB) and adapted to the end cap (EMEC). The hadronic end cap calorimeter (HEC) uses a copper-liquid argon sampling technique with flat plate geometry and is subdivided in depth in two wheels per end-cap. Finally, the forward calorimeter (FCAL) is composed of three modules employing cylindrical electrodes with thin liquid argon gaps.The construction of the full calorimeter system is complete since mid-2004. Production modules constructed in the home institutes were integrated into wheels at CERN in 2003-2004, and inserted into the three cryostats. They passed their first complete cold test before the lowering into the ATLAS cavern. Results of quality checks (e.g. electrical, mechanical, ...) performed on all the 190304 read-out channels after cool down will be reported. End 2004 the ATLAS barrel electromagnetic (EM) calorimeter was installed in the ATLAS cavern and since summer 2005 the front-end electronics are being connected and tested. Results of this first commissioning phase will be shown to demonstrate the high standards of quality control for our detectors

  5. The optical instrumentation of the ATLAS Tile Calorimeter

    Czech Academy of Sciences Publication Activity Database

    Abdallah, J.; Adragna, P.; Alexa, C.; Lokajíček, Miloš; Němeček, Stanislav; Přibyl, Lukáš

    2013-01-01

    Roč. 8, Jan (2013), P01005 ISSN 1748-0221 Institutional support: RVO:68378271 Keywords : calorimeters * calorimeter methods * scintillators * scintillation and light emission processes * solid, gas and liquid scintillators Subject RIV: BF - Elementary Particles and High Energy Physics Impact factor: 1.526, year: 2013

  6. A Customizable GeantV Calorimeter Application

    CERN Document Server

    Schmitz, Ryan; Vallecorsa, Sofia; Novak, Mihaly; CERN. Geneva. EP Department

    2017-01-01

    A customizable calorimeter application was written in GeantV. This application includes a GeantV-native detector construction file as well as GeantV-native physics models and new data collection structures. Including these features makes this one of the first examples of a completely standalone GeantV application. A comparison to Geant4 was made which showed the consistency of the GeantV-native physics models included in this example. Finally, the workflow improvements made by the creation of this application are described.

  7. ATLAS detector performance in Run1: Calorimeters

    CERN Document Server

    Burghgrave, B; The ATLAS collaboration

    2014-01-01

    ATLAS operated with an excellent efficiency during the Run 1 data taking period, recording respectively in 2011 and 2012 an integrated luminosity of 5.3 fb-1 at √s = 7 TeV and 21.6 fb-1 at √s = 8TeV. The Liquid Argon and Tile Calorimeter contributed to this effort by operating with a good data quality efficiency, improving over the whole Run 1. This poster presents the Run 1 overall status and performance, LS1 works and Preparations for Run 2.

  8. Neutron calorimeter as a fusion diagnostic

    International Nuclear Information System (INIS)

    Proctor, A.E.; Nieschmidt, E.B.

    1986-01-01

    A calorimeter is described which is applicable as a fusion neutron diagnostic. The device has the following distinct advantages: low sensitivity to thermal neutrons, large dynamic range, small mass resulting in fair time resolution, small physical size, independent calibration, little shielding required, no heat loss to surroundings, and low cost. The heat generation is provided by neutron induced fissions in a foil of 235 U or 238 U. The effects, advantages, and disadvantages of these target materials are discussed. The expected time resolution and dynamic range are estimated for both target materials

  9. Graphene nano-ink biosensor arrays on a microfluidic paper for multiplexed detection of metabolites

    Energy Technology Data Exchange (ETDEWEB)

    Labroo, Pratima; Cui, Yue, E-mail: yue.cui@usu.edu

    2014-02-01

    Graphical abstract: - Highlights: • We report graphene-ink biosensor arrays on a microfluidic paper for metabolites. • The device is able to detect multiple metabolites sensitively and rapidly. • The device fabrication process is simple and inexpensive. - Abstract: The development of a miniaturized and low-cost platform for the highly sensitive, selective and rapid detection of multiplexed metabolites is of great interest for healthcare, pharmaceuticals, food science, and environmental monitoring. Graphene is a delicate single-layer, two-dimensional network of carbon atoms with extraordinary electrical sensing capability. Microfluidic paper with printing technique is a low cost matrix. Here, we demonstrated the development of graphene-ink based biosensor arrays on a microfluidic paper for the multiplexed detection of different metabolites, such as glucose, lactate, xanthine and cholesterol. Our results show that the graphene biosensor arrays can detect multiple metabolites on a microfluidic paper sensitively, rapidly and simultaneously. The device exhibits a fast measuring time of less than 2 min, a low detection limit of 0.3 μM, and a dynamic detection range of 0.3–15 μM. The process is simple and inexpensive to operate and requires a low consumption of sample volume. We anticipate that these results could open exciting opportunities for a variety of applications.

  10. Readiness of the ATLAS Liquid Argon Calorimeter for LHC Collisions

    CERN Document Server

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Sankey, D.P.C.; Sanny, B.; Sansoni, A.; Santamarina Rios, C; Santi, L.; Santoni, C.; Santonico, R.; Santos, D.; Santos, J.; Saraiva, J.G.; Sarangi, T.; Sarkisyan-Grinbaum, E.; Sarri, F.; Sasaki, O.; Sasaki, T.; Sasao, N.; Satsounkevitch, I.; Sauvage, G.; Savard, P.; Savine, A.Y.; Savinov, V.; Sawyer, L.; Saxon, D.H.; Says, L.P.; Sbarra, C.; Sbrizzi, A.; Scannicchio, D.A.; Schaarschmidt, J.; Schacht, P.; Schäfer, U.; Schaetzel, S.; Schaffer, A.C.; Schaile, D.; Schamberger, R.D.; Schamov, A.G.; Schegelsky, V.A.; Scheirich, D.; Schernau, M.; Scherzer, M.I.; Schiavi, C.; Schieck, J.; Schioppa, M.; Schlenker, S.; Schlereth, J.L.; Schmid, P.; Schmidt, M.P.; Schmieden, K.; Schmitt, C.; Schmitz, M.; Schott, M.; Schouten, D.; Schovancova, J.; Schram, M.; Schreiner, A.; Schroeder, C.; Schroer, N.; Schroers, M.; Schuler, G.; Schultes, J.; Schultz-Coulon, H-C; Schumacher, J.; Schumacher, M.; Schumm, B.A.; Schune, Ph; Schwanenberger, C.; Schwartzman, A.; Schwemling, Ph; Schwienhorst, R.; Schwierz, R.; Schwindling, J.; Scott, W.G.; Searcy, J.; Sedykh, E.; Segura, E.; Seidel, S.C.; Seiden, A.; Seifert, F.; Seixas, J.M.; Sekhniaidze, G.; Seliverstov, D.M.; Sellden, B.; Seman, M.; Semprini-Cesari, N.; Serfon, C.; Serin, L.; Seuster, R.; Severini, H.; Sevior, M.E.; Sfyrla, A.; Shamim, M.; Shan, L.Y.; Shank, J.T.; Shao, Q.T.; Shapiro, M.; Shatalov, P.B.; Shaver, L.; Shaw, C.; Shaw, K.; Sherman, D.; Sherwood, P.; Shibata, A.; Shimojima, M.; Shin, T.; Shmeleva, A.; Shochet, M.J.; Shupe, M.A.; Sicho, P.; Sidoti, A.; Siebel, A.; Siegert, F.; Siegrist, J.; Sijacki, Dj; Silbert, O.; Silva, J.; Silver, Y.; Silverstein, D.; Silverstein, S.B.; Simak, V.; Simic, Lj; Simion, S.; Simmons, B.; Simonyan, M.; Sinervo, P.; Sinev, N.B.; Sipica, V.; Siragusa, G.; Sisakyan, A.N.; Sivoklokov, S.Yu.; Sjoelin, J.; Sjursen, T.B.; Skubic, P.; Skvorodnev, N.; Slater, M.; Slavicek, T.; Sliwa, K.; Sloper, J.; Sluka, T.; Smakhtin, V.; Smirnov, S.Yu.; Smirnov, Y.; Smirnova, L.N.; Smirnova, O.; Smith, B.C.; Smith, D.; Smith, K.M.; Smizanska, M.; Smolek, K.; Snesarev, A.A.; Snow, S.W.; Snow, J.; Snuverink, J.; Snyder, S.; Soares, M.; Sobie, R.; Sodomka, J.; Soffer, A.; Solans, C.A.; Solar, M.; Solfaroli-Camillocci, E.; Solodkov, A.A.; Solovyanov, O.V.; Soluk, R.; Sondericker, J.; Sopko, V.; Sopko, B.; Sosebee, M.; Sosnovtsev, V.V.; Sospedra-Suay, L.; Soukharev, A.; Spagnolo, S.; Spanò, F.; Speckmayer, P.; Spencer, E.; Spighi, R.; Spigo, G.; Spila, F.; Spiwoks, R.; Spousta, M.; Spreitzer, T.; Spurlock, B.; St Denis, R D; Stahl, T.; Stamen, R.; Stancu, S.N.; Stanecka, E.; Stanek, R.W.; Stanescu, C.; Stapnes, S.; Starchenko, E.A.; Stark, J.; Staroba, P.; Starovoitov, P.; Stastny, J.; Staude, A.; Stavina, P.; Stavropoulos, G.; Steinbach, P.; Steinberg, P.; Stekl, I.; Stelzer, B.; Stelzer, H.J.; Stelzer-Chilton, O.; Stenzel, H.; Stevenson, K.; Stewart, G.; Stockton, M.C.; Stoerig, K.; Stoicea, G.; Stonjek, S.; Strachota, P.; Stradling, A.; Straessner, A.; Strandberg, J.; Strandberg, S.; Strandlie, A.; Strauss, M.; Strizenec, P.; Ströhmer, R.; Strom, D.M.; Strong, J.A.; Stroynowski, R.; Strube, J.; Stugu, B.; Stumer, I.; Soh, D.A.; Su, D.; Suchkov, S.I.; Sugaya, Y.; Sugimoto, T.; Suhr, C.; Suk, M.; Sulin, V.V.; Sultansoy, S.; Sumida, T.; Sun, X.; Sundermann, J.E.; Suruliz, K.; Sushkov, S.; Susinno, G.; Sutton, M.R.; Suzuki, T.; Suzuki, Y.; Sviridov, Yu M; Sykora, I.; Sykora, T.; Szymocha, T.; Sánchez, J.; Ta, D.; Tackmann, K.; Taffard, A.; Tafirout, R.; Taga, A.; Takahashi, Y.; Takai, H.; Takashima, R.; Takeda, H.; Takeshita, T.; Talby, M.; Talyshev, A.; Tamsett, M.C.; Tanaka, J.; Tanaka, R.; Tanaka, S.; Tanaka, S.; Tappern, G.P.; Tapprogge, S.; Tardif, D.; Tarem, S.; Tarrade, F.; Tartarelli, G.F.; Tas, P.; Tasevsky, M.; Tassi, E.; Taylor, C.; Taylor, F.E.; Taylor, G.N.; Taylor, R.P.; Taylor, W.; Teixeira-Dias, P.; Ten Kate, H; Teng, P.K.; Terada, S.; Terashi, K.; Terron, J.; Terwort, M.; Testa, M.; Teuscher, R.J.; Tevlin, C.M.; Thadome, J.; Thananuwong, R.; Thioye, M.; Thoma, S.; Thomas, J.P.; Thomas, T.L.; Thompson, E.N.; Thompson, P.D.; Thompson, P.D.; Thompson, R.J.; Thompson, A.S.; Thomson, E.; Thun, R.P.; Tic, T.; Tikhomirov, V.O.; Tikhonov, Y.A.; Timmermans, C.J.W.P.; Tipton, P.; Tique-Aires-Viegas, F.J.; Tisserant, S.; Tobias, J.; Toczek, B.; Todorov, T.; Todorova-Nova, S.; Toggerson, B.; Tojo, J.; Tokár, S.; Tokushuku, K.; Tollefson, K.; Tomasek, L.; Tomasek, M.; Tomasz, F.; Tomoto, M.; Tompkins, D.; Tompkins, L.; Toms, K.; Tong, G.; Tonoyan, A.; Topfel, C.; Topilin, N.D.; Torrence, E.; Torró Pastor, E; Toth, J.; Touchard, F.; Tovey, D.R.; Tovey, S.N.; Trefzger, T.; Tremblet, L.; Tricoli, A.; Trigger, I.M.; Trincaz-Duvoid, S.; Trinh, T.N.; Tripiana, M.F.; Triplett, N.; Trivedi, A.; Trocmé, B.; Troncon, C.; Trzupek, A.; Tsarouchas, C.; Tseng, J.C-L.; Tsiafis, I.; Tsiakiris, M.; Tsiareshka, P.V.; Tsionou, D.; Tsipolitis, G.; Tsiskaridze, V.; Tskhadadze, E.G.; Tsukerman, I.I.; Tsulaia, V.; Tsung, J-W; Tsuno, S.; Tsybychev, D.; Turala, M.; Turecek, D.; Turk Cakir, I; Turlay, E.; Tuts, P.M.; Twomey, M.S.; Tylmad, M.; Tyndel, M.; Tzanakos, G.; Uchida, K.; Ueda, I.; Uhlenbrock, M.; Uhrmacher, M.; Ukegawa, F.; Unal, G.; Underwood, D.G.; Undrus, A.; Unel, G.; Unno, Y.; Urbaniec, D.; Urkovsky, E.; Urquijo, P.; Urrejola, P.; Usai, G.; Uslenghi, M.; Vacavant, L.; Vacek, V.; Vachon, B.; Vahsen, S.; Valenta, J.; Valente, P.; Valentinetti, S.; Valkar, S.; Valladolid Gallego, E; Vallecorsa, S.; Valls Ferrer, J A; Van Berg, R; van der Graaf, H; van der Kraaij, E; van der Poel, E; Van Der Ster, D; van Eldik, N; van Gemmeren, P; van Kesteren, Z; van Vulpen, I; Vandelli, W.; Vandoni, G.; Vaniachine, A.; Vankov, P.; Vannucci, F.; Varela Rodriguez, F; Vari, R.; Varnes, E.W.; Varouchas, D.; Vartapetian, A.; Varvell, K.E.; Vasilyeva, L.; Vassilakopoulos, V.I.; Vazeille, F.; Vegni, G.; Veillet, J.J.; Vellidis, C.; Veloso, F.; Veness, R.; Veneziano, S.; Ventura, A.; Ventura, D.; Venturi, M.; Venturi, N.; Vercesi, V.; Verducci, M.; Verkerke, W.; Vermeulen, J.C.; Vetterli, M.C.; Vichou, I.; Vickey, T.; Viehhauser, G.H.A.; Villa, M.; Villani, E.G.; Villaplana Perez, M; Villate, J.; Vilucchi, E.; Vincter, M.G.; Vinek, E.; Vinogradov, V.B.; Viret, S.; Virzi, J.; Vitale, A.; Vitells, O.V.; Vivarelli, I.; Vives Vaques, F; Vlachos, S.; Vlasak, M.; Vlasov, N.; Vogt, H.; Vokac, P.; Volpi, M.; Volpini, G.; von der Schmitt, H; von Loeben, J; von Radziewski, H; von Toerne, E; Vorobel, V.; Vorobiev, A.P.; Vorwerk, V.; Vos, M.; Voss, R.; Voss, T.T.; Vossebeld, J.H.; Vranjes, N.; Vranjes Milosavljevic, M; Vrba, V.; Vreeswijk, M.; Vu Anh, T; Vudragovic, D.; Vuillermet, R.; Vukotic, I.; Wagner, P.; Wahlen, H.; Walbersloh, J.; Walder, J.; Walker, R.; Walkowiak, W.; Wall, R.; Wang, C.; Wang, H.; Wang, J.; Wang, J.C.; Wang, S.M.; Ward, C.P.; Warsinsky, M.; Wastie, R.; Watkins, P.M.; Watson, A.T.; Watson, M.F.; Watts, G.; Watts, S.; Waugh, A.T.; Waugh, B.M.; Webel, M.; Weber, J.; Weber, M.D.; Weber, M.; Weber, M.S.; Weber, P.; Weidberg, A.R.; Weingarten, J.; Weiser, C.; Wellenstein, H.; Wells, P.S.; Wen, M.; Wenaus, T.; Wendler, S.; Wengler, T.; Wenig, S.; Wermes, N.; Werner, M.; Werner, P.; Werth, M.; Werthenbach, U.; Wessels, M.; Whalen, K.; Wheeler-Ellis, S.J.; Whitaker, S.P.; White, A.; White, M.J.; White, S.; Whiteson, D.; Whittington, D.; Wicek, F.; Wicke, D.; Wickens, F.J.; Wiedenmann, W.; Wielers, M.; Wienemann, P.; Wiglesworth, C.; Wiik, L.A.M.; Wildauer, A.; Wildt, M.A.; Wilhelm, I.; Wilkens, H.G.; Williams, E.; Williams, H.H.; Willis, W.; Willocq, S.; Wilson, J.A.; Wilson, M.G.; Wilson, A.; Wingerter-Seez, I.; Winklmeier, F.; Wittgen, M.; Wolter, M.W.; Wolters, H.; Wosiek, B.K.; Wotschack, J.; Woudstra, M.J.; Wraight, K.; Wright, C.; Wright, D.; Wrona, B.; Wu, S.L.; Wu, X.; Wulf, E.; Xella, S.; Xie, S.; Xie, Y.; Xu, D.; Xu, N.; Yamada, M.; Yamamoto, A.; Yamamoto, S.; Yamamura, T.; Yamanaka, K.; Yamaoka, J.; Yamazaki, T.; Yamazaki, Y.; Yan, Z.; Yang, H.; Yang, U.K.; Yang, Y.; Yang, Z.; Yao, W-M; Yao, Y.; Yasu, Y.; Ye, J.; Ye, S.; Yilmaz, M.; Yoosoofmiya, R.; Yorita, K.; Yoshida, R.; Young, C.; Youssef, S.P.; Yu, D.; Yu, J.; Yu, M.; Yu, X.; Yuan, J.; Yuan, L.; Yurkewicz, A.; Zaidan, R.; Zaitsev, A.M.; Zajacova, Z.; Zambrano, V.; Zanello, L.; Zarzhitsky, P.; Zaytsev, A.; Zeitnitz, C.; Zeller, M.; Zema, P.F.; Zemla, A.; Zendler, C.; Zenin, O.; Zenis, T.; Zenonos, Z.; Zenz, S.; Zerwas, D.; Zevi della Porta, G; Zhan, Z.; Zhang, H.; Zhang, J.; Zhang, Q.; Zhang, X.; Zhao, L.; Zhao, T.; Zhao, Z.; Zhemchugov, A.; Zheng, S.; Zhong, J.; Zhou, B.; Zhou, N.; Zhou, Y.; Zhu, C.G.; Zhu, H.; Zhu, Y.; Zhuang, X.; Zhuravlov, V.; Zilka, B.; Zimmermann, R.; Zimmermann, S.; Zimmermann, S.; Ziolkowski, M.; Zitoun, R.; Zivkovic, L.; Zmouchko, V.V.; Zobernig, G.; Zoccoli, A.; zur Nedden, M; Zutshi, V.

    2010-01-01

    The ATLAS liquid argon calorimeter has been operating continuously since August 2006. At this time, only part of the calorimeter was readout, but since the beginning of 2008, all calorimeter cells have been connected to the ATLAS readout system in preparation for LHC collisions. This paper gives an overview of the liquid argon calorimeter performance measured in situ with random triggers, calibration data, cosmic muons, and LHC beam splash events. Results on the detector operation, timing performance, electronics noise, and gain stability are presented. High energy deposits from radiative cosmic muons and beam splash events allow to check the intrinsic constant term of the energy resolution. The uniformity of the electromagnetic barrel calorimeter response along eta (averaged over phi) is measured at the percent level using minimum ionizing cosmic muons. Finally, studies of electromagnetic showers from radiative muons have been used to cross-check the Monte Carlo simulation. The performance results obtained u...

  11. Reactor Gamma Heat Measurements with Calorimeters and Thermoluminescence Dosimeters

    DEFF Research Database (Denmark)

    Haack, Karsten; Majborn, Benny

    1973-01-01

    Intercomparison measurements of reactor γ-ray heating were carried out with calorimeters and thermoluminescence dosimeters. Within the measurement uncertainties the two methods yield coincident results. In the actual measurement range thermoluminescence dosimeters are less accurate than calorimet......Intercomparison measurements of reactor γ-ray heating were carried out with calorimeters and thermoluminescence dosimeters. Within the measurement uncertainties the two methods yield coincident results. In the actual measurement range thermoluminescence dosimeters are less accurate than...... calorimeters, but possess advantages such as a small probe size and the possibility of making simultaneous measurements at many different positions. Hence, thermoluminescence dosimeters may constitute a valuable supplement to calorimeters for reactor γ-ray heating measurements....

  12. Continued studies of calorimeter performance at the Lawrence Livermore Laboratory

    International Nuclear Information System (INIS)

    Steward, S.A.; Tsugawa, R.T.

    1975-01-01

    Calibrations of two calorimeters used for tritium and plutonium assays were made. Data from three new standards of about 0.5, 1, and 5 W were added to the results of a previous report and analyzed together. The accuracies of both calorimeters appear to fall within the specified 0.5 percent, although the data now available for the large calorimeter is insufficient to permit a more definite conclusion. An expression of the bias correction for each calorimeter with respect to the sample power cannot be determined. The bias of the medium thermopile-type calorimeter tends to be positive, however, and that of the large resistance-bridge design appears to be negative

  13. Electromagnetic and Hadron Calorimeters in the MIPP Experiment

    International Nuclear Information System (INIS)

    Nigmanov, T. S.; Gustafson, H. R.; Longo, M. J.; Rajaram, D.

    2006-01-01

    The purpose of the MIPP experiment is to study the inclusive production of photons, pions, kaons, and nucleons produced in π, K, and p interactions on various targets using beams from the Main Injector at Fermilab. The purpose of the calorimeters is to measure the production of forward-going photons and neutrons. The electromagnetic calorimeter consists of 10 lead plates interspersed with proportional chambers followed by the hadron calorimeter with 64 steel plates interspersed with scintillator. We collected data with a variety of targets with beam energies from 5 GeV/c up to 120 GeV/c. The energy calibration of both calorimeters with electrons, pions, kaons and protons is discussed. The performance of the calorimeters was tested on a neutron sample

  14. Mechanical construction and installation of the ATLAS tile calorimeter

    Energy Technology Data Exchange (ETDEWEB)

    Abdallah, J [IFIC, Centro Mixto Universidad de Valencia-CSIC, E46100 Burjassot, Valencia (Spain); Adragna, P; Bosi, F [Pisa University and INFN, Pisa (Italy); Alexa, C; Boldea, V [Institute of Atomic Physics, Bucharest (Romania); Alves, R [LIP and FCTUC University of Coimbra (Portugal); Amaral, P; Andresen, X; Behrens, A; Blocki, J [CERN, Geneva (Switzerland); Ananiev, A [LIP and IDMEC-IST, Lisbon (Portugal); Anderson, K [University of Chicago, Chicago, Illinois (United States); Antonaki, A [University of Athens, Athens (Greece); Batusov, V [JINR, Dubna (Russian Federation); Bednar, P [Comenius University, Bratislava (Slovakia); Bergeaas, E; Bohm, C [Stockholm University, Stockholm (Sweden); Biscarat, C [LPC Clermont-Ferrand, Université Blaise Pascal, Clermont-Ferrand (France); Blanch, O; Blanchot, G [Institut de Fisica d' Altes Energies, Universitat Autònoma de Barcelona, Barcelona (Spain); others, and

    2013-11-01

    This paper summarises the mechanical construction and installation of the Tile Calorimeter for the ATLAS experiment at the Large Hadron Collider in CERN, Switzerland. The Tile Calorimeter is a sampling calorimeter using scintillator as the sensitive detector and steel as the absorber and covers the central region of the ATLAS experiment up to pseudorapidities ±1.7. The mechanical construction of the Tile Calorimeter occurred over a period of about 10 years beginning in 1995 with the completion of the Technical Design Report and ending in 2006 with the installation of the final module in the ATLAS cavern. During this period approximately 2600 metric tons of steel were transformed into a laminated structure to form the absorber of the sampling calorimeter. Following instrumentation and testing, which is described elsewhere, the modules were installed in the ATLAS cavern with a remarkable accuracy for a structure of this size and weight.

  15. Mechanical construction and installation of the ATLAS tile calorimeter

    International Nuclear Information System (INIS)

    Abdallah, J; Adragna, P; Bosi, F; Alexa, C; Boldea, V; Alves, R; Amaral, P; Andresen, X; Behrens, A; Blocki, J; Ananiev, A; Anderson, K; Antonaki, A; Batusov, V; Bednar, P; Bergeaas, E; Bohm, C; Biscarat, C; Blanch, O; Blanchot, G

    2013-01-01

    This paper summarises the mechanical construction and installation of the Tile Calorimeter for the ATLAS experiment at the Large Hadron Collider in CERN, Switzerland. The Tile Calorimeter is a sampling calorimeter using scintillator as the sensitive detector and steel as the absorber and covers the central region of the ATLAS experiment up to pseudorapidities ±1.7. The mechanical construction of the Tile Calorimeter occurred over a period of about 10 years beginning in 1995 with the completion of the Technical Design Report and ending in 2006 with the installation of the final module in the ATLAS cavern. During this period approximately 2600 metric tons of steel were transformed into a laminated structure to form the absorber of the sampling calorimeter. Following instrumentation and testing, which is described elsewhere, the modules were installed in the ATLAS cavern with a remarkable accuracy for a structure of this size and weight

  16. Progress on the Level-1 Calorimeter Trigger

    CERN Multimedia

    Eric Eisenhandler

    The Level-1 Calorimeter Trigger (L1Calo) has recently passed a number of major hurdles. The various electronic modules that make up the trigger are either in full production or are about to be, and preparations in the ATLAS pit are well advanced. L1Calo has three main subsystems. The PreProcessor converts analogue calorimeter signals to digital, associates the rather broad trigger pulses with the correct proton-proton bunch crossing, and does a final calibration in transverse energy before sending digital data streams to the two algorithmic trigger processors. The Cluster Processor identifies and counts electrons, photons and taus, and the Jet/Energy-sum Processor looks for jets and also sums missing and total transverse energy. Readout drivers allow the performance of the trigger to be monitored online and offline, and also send region-of-interest information to the Level-2 Trigger. The PreProcessor (Heidelberg) is the L1Calo subsystem with the largest number of electronic modules (124), and most of its fu...

  17. The ZEUS calorimeter first level trigger

    International Nuclear Information System (INIS)

    Smith, W.H.; Ali, I.; Behrens, B.; Fordham, C.; Foudas, C.; Goussiou, A.; Jaworski, M.; Kinnel, T.; Lackey, J.; Robl, P.; Silverstein, S.; Dawson, J.W.; Krakauer, D.A.; Talaga, R.L.; Schlereth, J.L.

    1994-10-01

    The design of the ZEUS Calorimeter First Level Trigger (CFLT) is presented. The CFLT utilizes a pipelined architecture to provide trigger data for a global first leel trigger decision 5 μsec after each beam crossing, occurring every 96 nsec. The charges from 13K phototubes are summed into 1792 trigger tower pulseheights which are digitized by flash ADC's. The digital values are linearized, stored and used for sums and pattern tests. Summary data is forwarded to the Global First Level Trigger for each crossing 2 μsec after the crossing occurred. The CFLT determines the total energy, the total transverse energy, the missing energy, and the energy and number of isolated electrons and muons. It also provides information on the electromagnetic and hadronic energy deposited in various regions of the calorimeter. The CFLT has kept the experimental trigger rate below ∼200 Hz at the highest luminosity experienced at HERA. Performance studies suggest that the CFLT will keep the trigger rate below 1 kHZ against a rate of proton-beam gas interactions on the order of the 100 kHz expected at design luminosity. (orig.)

  18. Upgrading the ATLAS Tile Calorimeter Electronics

    CERN Document Server

    Popeneciu, G; The ATLAS collaboration

    2014-01-01

    The Tile Calorimeter (TileCal) is the central hadronic calorimeter of the ATLAS experiment at LHC. Around 2023, after the upgrade of the LHC (High Luminosity LHC, phase 2) the peak luminosity will increase by a factor of 5 compared to the design value (1034 cm-2 s-1), thus requiring an upgrade of the TileCal readout electronics. Except the 9852 photomultipliers (PMTs), most of the on- and off-detector electronics will be replaced, with the aim of digitizing all PMT pulses at 40 MHz at the front-end level and sending them with 10 Gbps optical links to the back-end electronics. Moreover, to increase reliability, redundancy will be introduced at different levels. Three different options are currently being investigated for the front-end electronics and extensive test beam studies are planned to select the best option. One demonstrator prototype module is also planned to be inserted in TileCal in 2014 that will include hybrid electronic components able to probe the new design, but still compatible with the presen...

  19. Level-1 Calorimeter Trigger starts firing

    CERN Multimedia

    Stephen Hillier

    2007-01-01

    L1Calo is one of the major components of ATLAS First Level trigger, along with the Muon Trigger and Central Trigger Processor. It forms all of the first-level calorimeter-based triggers, including electron, jet, tau and missing ET. The final system consists of over 250 custom designed 9U VME boards, most containing a dense array of FPGAs or ASICs. It is subdivided into a PreProcessor, which digitises the incoming trigger signals from the Liquid Argon and Tile calorimeters, and two separate processor systems, which perform the physics algorithms. All of these are highly flexible, allowing the possibility to adapt to beam conditions and luminosity. All parts of the system are read out through Read-Out Drivers, which provide monitoring data and Region of Interest (RoI) information for the Level-2 trigger. Production of the modules is now essentially complete, and enough modules exist to populate the full scale system in USA15. Installation is proceeding rapidly - approximately 90% of the final modules are insta...

  20. COTS Analog Prototype for LHCb's Calorimeter Upgrade

    CERN Document Server

    Abellan Beteta, Carlos; Herms i Berenguer, Atilà

    The objective of this thesis is to present a proposal for the analogue signal processing chain needed for the LHCb calorimeter upgrade improving the design used originally. The design contains several novelties: the system was designed with low noise in mind from the beginning, it is made to have good immunity to interferences stressing the fact that the board will be shared with large digital circuits, differential operational amplifiers are used in a non-standard way as a mean to obtain opposite polarity signals for the signal treatment and a way to increase the available signal in the front end electronics is proposed. The thesis starts with a brief introduction to the detector and its environment. This is followed by an explanation of the use of shapers in high energy physics detectors and the constraints that the shaper must address in the LHCb calorimeter. This leads to a chapter where the circuit design is explained starting from the analysis of the original circuit and its flaws. Once the original cir...

  1. The ZEUS calorimeter first level trigger

    Science.gov (United States)

    Silverstein, S.; Ali, I.; Behrens, B.; Foudas, C.; Fordham, C.; Goussiou, A.; Jaworski, M.; Lackey, J.; Reeder, D.; Robl, P.; Smith, W. H.; Vaiciulis, A.; Wodarczyk, M.; Dawson, J.; Krakauer, D.; Talaga, R.; Schlereth, J.; Zhang, H.

    1995-02-01

    An overview of the ZEUS calorimeter first level trigger is presented. The CFLT uses a pipelined architecture to accept and analyze calorimeter data for every 96 ns beam crossing interval. PMT signals are combined by analog electronics into electromagnetic and hadronic sums for 896 trigger towers. The analog sums are then digitized and analyzed. The CFLT determines the total, transverse, and missing transverse energy, identifies isolated electrons and muons, and sums energies in programmable subregions. Calculations are performed in 96 ns steps, and new data are accepted for every beam crossing. Trigger data are forwarded to the global first level trigger (GFLT) after 2 μs, allowing a GFLT accept to be issued 5 μs after the beam crossing which produced the event. Important features of the CFLT include a 12-bit effective dynamic range, extensive use of memory lookup tables for trigger calculations, fast pattern searches for isolated leptons, and low electronics noise. During the 1993 HERA run, the CFLT reduced a 50 kHz background rate to around 100 Hz.

  2. Liquid Argon Calorimeter performance at High Rates

    CERN Document Server

    Seifert, F; The ATLAS collaboration

    2013-01-01

    The expected increase of luminosity at HL-LHC by a factor of ten with respect to LHC luminosities has serious consequences for the signal reconstruction, radiation hardness requirements and operations of the ATLAS liquid argon calorimeters in the endcap, respectively forward region. Small modules of each type of calorimeter have been built and exposed to a high intensity proton beam of 50 GeV at IHEP/Protvino. The beam is extracted via the bent crystal technique, offering the unique opportunity to cover intensities ranging from $10^6$ p/s up to $3\\cdot10^{11}$ p/s. This exceeds the deposited energy per time expected at HL-LHC by more than a factor of 100. The correlation between beam intensity and the read-out signal has been studied. The data show clear indications of pulse shape distortion due to the high ionization build-up, in agreement with MC expectations. This is also confirmed from the dependence of the HV currents on beam intensity.

  3. Optimization of transition-edge calorimeter performance

    International Nuclear Information System (INIS)

    Ullom, J.N.; Beall, J.A.; Doriese, W.B.; Duncan, W.D.; Ferreira, L.; Hilton, G.C.; Irwin, K.D.; O'Neil, G.C.; Reintsema, C.D.; Vale, L.R.; Zink, B.L.

    2006-01-01

    Calorimeters that exploit the superconducting-to-normal transition are used to detect individual photons from near-infrared to γ-ray wavelengths. Across this wide range, absorption efficiency, speed, and energy resolution are key performance parameters. Here, we describe recent improvements in the resolution of X-ray and γ-ray transition-edge sensors (TESs). Using the measured dependencies of the high-frequency unexplained noise in TESs, we have optimized the design of our TES X-ray sensors and achieved FWHM energy resolutions of 2.4 eV at 5.9 keV in Constellation-X style sensors and ∼2.9 eV at 5.9 keV in larger sensors suitable for materials analysis. We have also achieved a FWHM energy resolution of 42 eV at 103 keV in a TES calorimeter optimized for the detection of hard X-rays and γ-rays

  4. Ice matrix in reconfigurable microfluidic systems

    Energy Technology Data Exchange (ETDEWEB)

    Bossi, A M [Department of Biotechnology, University of Verona, Strada Le Grazie 15, I-37134, Verona (Italy); Vareijka, M; Piletska, E V; Turner, A P F; Piletsky, S A [Cranfield Health, Cranfield University, Vincent Building B52, Cranfield, Bedfordshire, MK43 0AL (United Kingdom); Meglinski, I [Department of Physics, University of Otago, PO Box 56, Dunedin, 9054 (New Zealand)

    2013-07-01

    Microfluidic devices find many applications in biotechnologies. Here, we introduce a flexible and biocompatible microfluidic ice-based platform with tunable parameters and configuration of microfluidic patterns that can be changed multiple times during experiments. Freezing and melting of cavities, channels and complex relief structures created and maintained in the bulk of ice by continuous scanning of an infrared laser beam are used as a valve action in microfluidic systems. We demonstrate that pre-concentration of samples and transport of ions and dyes through the open channels created can be achieved in ice microfluidic patterns by IR laser-assisted zone melting. The proposed approach can be useful for performing separation and sensing processes in flexible reconfigurable microfluidic devices. (paper)

  5. Ice matrix in reconfigurable microfluidic systems

    International Nuclear Information System (INIS)

    Bossi, A M; Vareijka, M; Piletska, E V; Turner, A P F; Piletsky, S A; Meglinski, I

    2013-01-01

    Microfluidic devices find many applications in biotechnologies. Here, we introduce a flexible and biocompatible microfluidic ice-based platform with tunable parameters and configuration of microfluidic patterns that can be changed multiple times during experiments. Freezing and melting of cavities, channels and complex relief structures created and maintained in the bulk of ice by continuous scanning of an infrared laser beam are used as a valve action in microfluidic systems. We demonstrate that pre-concentration of samples and transport of ions and dyes through the open channels created can be achieved in ice microfluidic patterns by IR laser-assisted zone melting. The proposed approach can be useful for performing separation and sensing processes in flexible reconfigurable microfluidic devices. (paper)

  6. Ice matrix in reconfigurable microfluidic systems

    Science.gov (United States)

    Bossi, A. M.; Vareijka, M.; Piletska, E. V.; Turner, A. P. F.; Meglinski, I.; Piletsky, S. A.

    2013-07-01

    Microfluidic devices find many applications in biotechnologies. Here, we introduce a flexible and biocompatible microfluidic ice-based platform with tunable parameters and configuration of microfluidic patterns that can be changed multiple times during experiments. Freezing and melting of cavities, channels and complex relief structures created and maintained in the bulk of ice by continuous scanning of an infrared laser beam are used as a valve action in microfluidic systems. We demonstrate that pre-concentration of samples and transport of ions and dyes through the open channels created can be achieved in ice microfluidic patterns by IR laser-assisted zone melting. The proposed approach can be useful for performing separation and sensing processes in flexible reconfigurable microfluidic devices.

  7. Novel approach based on one-tube nested PCR and a lateral flow strip for highly sensitive diagnosis of tuberculous meningitis.

    Science.gov (United States)

    Sun, Yajuan; Chen, Jiajun; Li, Jia; Xu, Yawei; Jin, Hui; Xu, Na; Yin, Rui; Hu, Guohua

    2017-01-01

    Rapid and sensitive detection of Mycobacterium tuberculosis (M. Tb) in cerebrospinal fluid is crucial in the diagnosis of tuberculous meningitis (TBM), but conventional diagnostic technologies have limited sensitivity and specificity or are time-consuming. In this work, a novel, highly sensitive molecular diagnostic method, one-tube nested PCR-lateral flow strip test (OTNPCR-LFST), was developed for detecting M. tuberculosis. This one-tube nested PCR maintains the sensitivity of conventional two-step nested PCR and reduces both the chance of cross-contamination and the time required for analysis. The PCR product was detected by a lateral flow strip assay, which provided a basis for migration of the test to a point-of-care (POC) microfluidic format. The developed assay had an improved sensitivity compared with traditional PCR, and the limit of detection was up to 1 fg DNA isolated from M. tuberculosis. The assay was also specific for M. tuberculosis, and no cross-reactions were found in other non-target bacteria. The application of this technique to clinical samples was successfully evaluated, and OTNPCR-LFST showed 89% overall sensitivity and 100% specificity for TBM patients. This one-tube nested PCR-lateral flow strip assay is useful for detecting M. tuberculosis in TBM due to its rapidity, high sensitivity and simple manipulation.

  8. Nanostructures for all-polymer microfluidic systems

    DEFF Research Database (Denmark)

    Matschuk, Maria; Bruus, Henrik; Larsen, Niels Bent

    2010-01-01

    antistiction coating was found to improve the replication fidelity (shape and depth) of nanoscale features substantially. Arrays of holes of 50 nm diameter/35 nm depth and 100 nm/100 nm diameter, respectively, were mass-produced in cyclic olefin copolymer (Topas 5013) by injection molding. Polymer microfluidic...... channel chip parts resulted from a separate injection molding process. The microfluidic chip part and the nanostructured chip part were successfully bonded to form a sealed microfluidic system using air plasma assisted thermal bonding....

  9. Microfluidic high gradient magnetic cell separation

    Science.gov (United States)

    Inglis, David W.; Riehn, Robert; Sturm, James C.; Austin, Robert H.

    2006-04-01

    Separation of blood cells by native susceptibility and by the selective attachment of magnetic beads has recently been demonstrated on microfluidic devices. We discuss the basic principles of how forces are generated via the magnetic susceptibility of an object and how microfluidics can be combined with micron-scale magnetic field gradients to greatly enhance in principle the fractionating power of magnetic fields. We discuss our efforts and those of others to build practical microfluidic devices for the magnetic separation of blood cells. We also discuss our attempts to integrate magnetic separation with other microfluidic features for developing handheld medical diagnostic tools.

  10. Integrated lenses in polystyrene microfluidic devices

    KAUST Repository

    Fan, Yiqiang

    2013-04-01

    This paper reports a new method for integrating microlenses into microfluidic devices for improved observation. Two demonstration microfluidic devices were provided which were fabricated using this new technique. The integrated microlenses were fabricated using a free-surface thermo-compression molding method on a polystyrene (PS) sheet which was then bonded on top of microfluidic channels as a cover plate, with the convex microlenses providing a magnified image of the channel for the easier observation of the flow in the microchannels. This approach for fabricating the integrated microlens in microfluidic devices is rapid, low cost and without the requirement of cleanroom facilities. © 2013 IEEE.

  11. Design, Performance, and Calibration of the CMS Hadron-Outer Calorimeter

    CERN Document Server

    Abdullin, Salavat; Acharya, Bannaje Sripathi; Adam, Nadia; Adams, Mark Raymond; Akchurin, Nural; Akgun, Ugur; Albayrak, Elif Asli; Anderson, E Walter; Antchev, Georgy; Arcidy, M; Ayan, S; Aydin, Sezgin; Aziz, Tariq; Baarmand, Marc M; Babich, Kanstantsin; Baden, Drew; Bakirci, Mustafa Numan; Banerjee, Sunanda; Banerjee, Sudeshna; Bard, Robert; Barnes, Virgil E; Bawa, Harinder Singh; Baiatian, G; Bencze, Gyorgy; Beri, Suman Bala; Berntzon, Lisa; Bhatnagar, Vipin; Bhatti, Anwar; Bodek, Arie; Bose, Suvadeep; Bose, Tulika; Budd, Howard; Burchesky, Kyle; Camporesi, Tiziano; Cankocak, Kerem; Carrell, Kenneth Wayne; Cerci, Salim; Chendvankar, Sanjay; Chung, Yeon Sei; Clarida, Warren; Cremaldi, Lucien Marcus; Cushman, Priscilla; Damgov, Jordan; De Barbaro, Pawel; Debbins, Paul; Deliomeroglu, Mehmet; Demianov, A; de Visser, Theo; Deshpande, Pandurang Vishnu; Díaz, Jonathan; Dimitrov, Lubomir; Dugad, Shashikant; Dumanoglu, Isa; Duru, Firdevs; Efthymiopoulos, I; Elias, John E; Elvira, D; Emeliantchik, Igor; Eno, Sarah Catherine; Ershov, Alexander; Erturk, Sefa; Esen, Selda; Eskut, Eda; Fenyvesi, Andras; Fisher, Wade Cameron; Freeman, Jim; Ganguli, Som N; Gaultney, Vanessa; Gamsizkan, Halil; Gavrilov, Vladimir; Genchev, Vladimir; Gleyzer, Sergei V; Golutvin, Igor; Goncharov, Petr; Grassi, Tullio; Green, Dan; Gribushin, Andrey; Grinev, B; Gurtu, Atul; Murat Güler, A; Gülmez, Erhan; Gümüs, K; Haelen, T; Hagopian, Sharon; Hagopian, Vasken; Halyo, Valerie; Hashemi, Majid; Hauptman, John M; Hazen, Eric; Heering, Arjan Hendrix; Heister, Arno; Hunt, Adam; Ilyina, N; Ingram, D; Isiksal, Engin; Jarvis, Chad; Jeong, Chiyoung; Johnson, Kurtis F; Jones, John; Kaftanov, Vitali; Kalagin, Vladimir; Kalinin, Alexey; Kalmani, Suresh Devendrappa; Karmgard, Daniel John; Kaur, Manjit; Kaya, Mithat; Kaya, Ozlem; Kayis-Topaksu, A; Kellogg, Richard G; Khmelnikov, Alexander; Kim, Heejong; Kisselevich, I; Kodolova, Olga; Kohli, Jatinder Mohan; Kolossov, V; Korablev, Andrey; Korneev, Yury; Kosarev, Ivan; Kramer, Laird; Krinitsyn, Alexander; Krishnaswamy, Marthi Ramaswamy; Krokhotin, Andrey; Kryshkin, V; Kuleshov, Sergey; Kumar, Arun; Kunori, Shuichi; Laasanen, Alvin T; Ladygin, Vladimir; Laird, Edward; Landsberg, Greg; Laszlo, Andras; Lawlor, C; Lazic, Dragoslav; Lee, Sang Joon; Levchuk, Leonid; Linn, Stephan; Litvintsev, Dmitri; Lobolo, L; Los, Serguei; Lubinsky, V; Lukanin, Vladimir; Ma, Yousi; Machado, Emanuel; Maity, Manas; Majumder, Gobinda; Mans, Jeremy; Marlow, Daniel; Markowitz, Pete; Martínez, German; Mazumdar, Kajari; Merlo, Jean-Pierre; Mermerkaya, Hamit; Mescheryakov, G; Mestvirishvili, Alexi; Miller, Michael; Möller, A; Mohammadi-Najafabadi, M; Moissenz, P; Mondal, Naba Kumar; Mossolov, Vladimir; Nagaraj, P; Narasimham, Vemuri Syamala; Norbeck, Edwin; Olson, Jonathan; Onel, Yasar; Onengüt, G; Ozkan, Cigdem; Ozkurt, Halil; Ozkorucuklu, Suat; Ozok, Ferhat; Paktinat, S; Pal, Andras; Patil, Mandakini Ravindra; Penzo, Aldo; Petrushanko, Sergey; Petrosian, A; Pikalov, Vladimir; Piperov, Stefan; Podrasky, V; Polatoz, A; Pompos, Arnold; Popescu, Sorina; Posch, C; Pozdnyakov, Andrey; Qian, Weiming; Ralich, Robert; Reddy, L; Reidy, Jim; Rogalev, Evgueni; Roh, Youn; Rohlf, James; Ronzhin, Anatoly; Ruchti, Randy; Ryazanov, Anton; Safronov, Grigory; Sanders, David A; Sanzeni, Christopher; Sarycheva, Ludmila; Satyanarayana, B; Schmidt, Ianos; Sekmen, Sezen; Semenov, Sergey; Senchishin, V; Sergeyev, S; Serin, Meltem; Sever, Ramazan; Singh, B; Singh, Jas Bir; Sirunyan, Albert M; Skuja, Andris; Sharma, Seema; Sherwood, Brian; Shumeiko, Nikolai; Smirnov, Vitaly; Sogut, Kenan; Sonmez, Nasuf; Sorokin, Pavel; Spezziga, Mario; Stefanovich, R; Stolin, Viatcheslav; Sudhakar, Katta; Sulak, Lawrence; Suzuki, Ichiro; Talov, Vladimir; Teplov, Konstantin; Thomas, Ray; Tonwar, Suresh C; Topakli, Huseyin; Tully, Christopher; Turchanovich, L; Ulyanov, A; Vanini, A; Vankov, Ivan; Vardanyan, Irina; Varela, F; Vergili, Mehmet; Verma, Piyush; Vesztergombi, Gyorgy; Vidal, Richard; Vishnevskiy, Alexander; Vlassov, E; Vodopiyanov, Igor; Volobouev, Igor; Volkov, Alexey; Volodko, Anton; Wang, Lei; Werner, Jeremy Scott; Wetstein, Matthew; Winn, Dave; Wigmans, Richard; Whitmore, Juliana; Wu, Shouxiang; Yazgan, Efe; Yetkin, Taylan; Zálán, Peter; Zarubin, Anatoli; Zeyrek, Mehmet

    2008-01-01

    The CMS hadron calorimeter is a sampling calorimeter with brass absorber and plastic scintillator tiles with wavelength shifting fibres for carrying the light to the readout device. The barrel hadron calorimeter is complemented with an outer calorimeter to ensure high energy shower containment in the calorimeter. Fabrication, testing and calibration of the outer hadron calorimeter are carried out keeping in mind its importance in the energy measurement of jets in view of linearity and resolution. It will provide a net improvement in missing $\\et$ measurements at LHC energies. The outer hadron calorimeter will also be used for the muon trigger in coincidence with other muon chambers in CMS.

  12. Implementation of linear bias corrections for calorimeters at Mound

    International Nuclear Information System (INIS)

    Barnett, T.M.

    1993-01-01

    In the past, Mound has generally made relative bias corrections as part of the calibration of individual calorimeters. The correction made was the same over the entire operating range of the calorimeter, regardless of the magnitude of the range. Recently, an investigation was performed to check the relevancy of using linear bias corrections to calibrate the calorimeters. The bias is obtained by measuring calibrated plutonium and/or electrical heat standards over the operating range of the calorimeter. The bias correction is then calculated using a simple least squares fit (y = mx + b) of the bias in milliwatts over the operating range of the calorimeter in watts. The equation used is B i = B 0 + (B w * W m ), where B i is the bias at any given power in milliwatts, B 0 is the intercept (absolute bias in milliwatts), B w is the slope (relative bias in milliwatts per watt), and W m is the measured power in watts. The results of the study showed a decrease in the random error of bias corrected data for most of the calorimeters which are operated over a large wattage range (greater than an order of magnitude). The linear technique for bias correction has been fully implemented at Mound and has been included in the Technical Manual, ''A Measurement Control Program for Radiometric Calorimeters at Mound'' (MD-21900)

  13. Status of the ATLAS Liquid Argon Calorimeter and its Performance

    CERN Document Server

    Barillari, T; The ATLAS collaboration

    2011-01-01

    The ATLAS experiment is designed to study the proton-proton collisions produced at the LHC with a centre-of-mass energy of 14 TeV. Liquid argon (LAr) sampling calorimeters are used in ATLAS for all electromagnetic calorimetry covering the pseudorapidity region |eta|<3.2, as well as for hadronic calorimetry from |eta|=1.4 to |eta|=4.8. The calorimeter system consists of an electromagnetic barrel calorimeter and two endcaps with electromagnetic (EMEC), hadronic (HEC) and forward (FCAL) calorimeters. The lead-liquid argon sampling technique with an accordion geometry was chosen for the barrel electromagnetic calorimeter (EMB) and adapted to the endcap (EMEC). This geometry allows a uniform acceptance over the whole azimuthal range without any gap. The hadronic endcap calorimeter (HEC) uses a copper-liquid argon sampling technique with plate geometry and is subdivided into two wheels in depth per end-cap. Finally, the forward calorimeter (FCAL) is composed of three modules featuring cylindrical electrodes ...

  14. The ATLAS hadronic tile calorimeter from construction toward physics

    CERN Document Server

    Adragna, P; Anderson, K; Antonaki, A; Batusov, V; Bednar, P; Binet, S; Biscarat, C; Blanchot, G; Bogush, A A; Bohm, C; Boldea, V; Bosman, M; Bromberg, C; Budagov, Yu A; Caloba, L; Calvet, D; Carvalho, J; Castelo, J; Castillo, M V; Sforza, M C; Cavasinni, V; Cerqueira, A S; Chadelas, R; Costanzo, D; Cogswell, F; Constantinescu, S; Crouau, M; Cuenca, C; Damazio, D O; Daudon, F; David, M; Davidek, T; De, K; Del Prete, T; Di Girolamo, B; Dita, S; Dolejsi, J; Dolezal, Z; Dotti, A; Downing, R; Efthymiopoulos, I; Errede, D; Errede, S; Farbin, A; Fassouliotis, D; Fedorko, I; Fenyuk, A; Ferdi, C; Ferrer, A; Flaminio, V; Fullana, E; Garde, V; Giakoumopoulou, V; Gildemeister, O; Gilewsky, V; Giangiobbe, V; Giokaris, N; Gomes, A; González, V; Grabskii, V; Grenier, P; Gris, P; Guarino, V; Guicheney, C; Sen-Gupta, A; Hakobyan, H; Haney, M; Henriques, A; Higón, E; Holmgren, S O; Hurwitz, M; Huston, J; Iglesias, C; And, K J; Junk, T; Karyukhin, A N; Khubua, J; Klereborn, J; Korolkov, I Ya; Krivkova, P; Kulchitskii, Yu A; Kurochkin, Yu; Kuzhir, P; Lambert, D; Le Compte, T; Lefèvre, R; Leitner, R; Lembesi, M; Li, J; Liablin, M; Lokajícek, M; Lomakin, Y; Amengual, J M L; Lupi, A; Maidantchik, C; Maio, A; Maliukov, S; Manousakis, A; Marques, C; Marroquim, F; Martin, F; Mazzoni, E; Montarou, G; Merritt, F S; Myagkov, A; Miller, R; Minashvili, I A; Miralles, L; Némécek, S; Nessi, M; Nodulman, L; Norniella, O; Onofre, A; Oreglia, M J; Pantea, D; Pallin, D; Pilcher, J E; Pina, J; Pinhão, J; Podlyski, F; Portell, X; Poveda, J; Price, L E; Pribyl, L; Proudfoot, J; Ramstedt, M; Reinmuth, G; Richards, R; Roda, C; Romanov, V; Rosnet, P; Roy, P; Rumiantsau, V; Russakovich, N; Salto, O; Salvachúa, B; Sanchis, E; Sanders, H; Santoni, C; Santos, J; Saraiva, J G; Sarri, F; Satsunkevich, I S; Says, L P; Schlager, G; Schlereth, J L; Seixas, J M; Selldén, B; Shevtsov, P; Shochet, M; Da Silva, P; Silva, J; Simaitis, V; Sissakian, A N; Solodkov, A; Solovyanov, O; Sosebee, M; Spanó, F; Stanek, R; Starchenko, E A; Starovoitov, P; Suk, M; Sykora, I; Tang, F; Tas, P; Teuscher, R; Tokar, S; Topilin, N; Torres, J; Tsulaia, V; Underwood, D; Usai, G; Valkár, S; Valls, J A; Vartapetian, A H; Vazeille, F; Vichou, I; Vinogradov, V; Vivarelli, I; Volpi, M; White, A; Zaitsev, A; Zenine, A; Zenis, T

    2006-01-01

    The Tile Calorimeter, which constitutes the central section of the ATLAS hadronic calorimeter, is a non-compensating sampling device made of iron and scintillating tiles. The construction phase of the calorimeter is nearly complete, and most of the effort now is directed toward the final assembly and commissioning in the underground experimental hall. The layout of the calorimeter and the tasks carried out during construction are described, first with a brief reminder of the requirements that drove the calorimeter design. During the last few years a comprehensive test-beam program has been followed in order to establish the calorimeter electromagnetic energy scale, to study its uniformity, and to compare real data to Monte Carlo simulation. The test-beam setup and first results from the data are described. During the test-beam period in 2004, lasting several months, data have been acquired with a complete slice of the central ATLAS calorimeter. The data collected in the test-beam are crucial in order to study...

  15. METROLOGICAL PERFORMANCES OF BOMB CALORIMETERS AT REAL CONDITIONS

    Directory of Open Access Journals (Sweden)

    Yu. V. Maksimuk

    2016-01-01

    Full Text Available The high-usage measurement equipment for heat of combustion of organic fuels are bomb isoperibol calorimeters with a water thermostat. The stability of work of calorimeters at real conditions is important for maintenance of reliability of measurement results. The article purpose – the analysis of stability for parameters of calorimeters to environment changes. In this work influence room temperature (Тк and heat exchange conditions on metrological characteristics of two models of calorimeters is considered with different degree of thermal protection: V-08МА and BIC 100. For calorimeters V-08МА the increase in a effective heat capacity (W on 0,1 % by growth of Tк on everyone 5 °С is established. To use value W in all interval laboratory temperatures Tк = 14–28 °С it is necessary to correct W on 2,8 J/°C on everyone 1 °С changes of Tк. Updating W is required, if the correction exceeds error in determination W. For calorimeter BIC 100 it is not revealed dependences W from Tк. BIC 100 have constant-temperature cap, high stability a temperature in thermostat and stabilized heat exchange. It is established that an standard deviation of cooling constant for all calorimeters in direct proportional to standard deviation W. 

  16. Development of a portable graphite calorimeter for photons and electrons

    International Nuclear Information System (INIS)

    McEwen, M.R.; Duane, S.

    1999-01-01

    The aim of this project is to develop a calorimeter for use in both electron and photon beams. The calorimeter should be more robust than the present NPL primary standard X-ray calorimeter and is designed to be sufficiently portable to enable measurements at clinical accelerators away from NPL. Although intended for therapy-level dosimetry, the new calorimeter can also be used for high-dose measurements at industrial facilities. The system consists of a front end (the calorimeter itself), means for thermal isolation and temperature control, and a measurement system based on thermistors in a DC Wheatstone bridge. The early part of the project focused on the development of a temperature control system sensitive enough to allow measurements of temperature rises of the order of 1 mK. The control system responds to the calorimeter, phantom and air temperatures and maintains the temperature of the calorimeter to within ± 0.2 mK over several hours. Initial operation at NPL in 6, 10 and 16 MV X-ray beams show that the system is capable of measurements of 1 Gy at 2 Gy/min with a random uncertainty of ± 0.5% (1 standard deviation). (author)

  17. Testbeam studies of production modules of the ATLAS Tile Calorimeter

    International Nuclear Information System (INIS)

    Adragna, P.; Alexa, C.; Anderson, K.; Antonaki, A.; Arabidze, A.; Batkova, L.; Batusov, V.; Beck, H.P.; Bednar, P.; Bergeaas Kuutmann, E.; Biscarat, C.; Blanchot, G.; Bogush, A.; Bohm, C.; Boldea, V.; Bosman, M.; Bromberg, C.; Budagov, J.; Burckhart-Chromek, D.; Caprini, M.

    2009-01-01

    We report test beam studies of 11% of the production ATLAS Tile Calorimeter modules. The modules were equipped with production front-end electronics and all the calibration systems planned for the final detector. The studies used muon, electron and hadron beams ranging in energy from 3 to 350 GeV. Two independent studies showed that the light yield of the calorimeter was ∼70pe/GeV, exceeding the design goal by 40%. Electron beams provided a calibration of the modules at the electromagnetic energy scale. Over 200 calorimeter cells the variation of the response was 2.4%. The linearity with energy was also measured. Muon beams provided an intercalibration of the response of all calorimeter cells. The response to muons entering in the ATLAS projective geometry showed an RMS variation of 2.5% for 91 measurements over a range of rapidities and modules. The mean response to hadrons of fixed energy had an RMS variation of 1.4% for the modules and projective angles studied. The response to hadrons normalized to incident beam energy showed an 8% increase between 10 and 350 GeV, fully consistent with expectations for a noncompensating calorimeter. The measured energy resolution for hadrons of σ/E=52.9%/√(E)+5.7% was also consistent with expectations. Other auxiliary studies were made of saturation recovery of the readout system, the time resolution of the calorimeter and the performance of the trigger signals from the calorimeter.

  18. Testbeam studies of production modules of the ATLAS Tile Calorimeter

    Energy Technology Data Exchange (ETDEWEB)

    Adragna, P [Pisa University and INFN, Pisa (Italy); Alexa, C [National Institute for Physics and Nuclear Engineering, Bucharest (Romania); Anderson, K [University of Chicago, Chicago, Illinois (United States); Antonaki, A; Arabidze, A [University of Athens, Athens (Greece); Batkova, L [Comenius University, Bratislava (Slovakia); Batusov, V [JINR, Dubna (Russian Federation); Beck, H P [Laboratory for High Energy Physics, University of Bern (Switzerland); Bednar, P [Comenius University, Bratislava (Slovakia); Bergeaas Kuutmann, E [Stockholm University, Stockholm (Sweden); Biscarat, C [LPC Clermont-Ferrand, Universite Blaise Pascal, Clermont-Ferrand (France); Blanchot, G [Institut de Fisica d' Altes Energies, Universitat Autonoma de Barcelona, Barcelona (Spain); Bogush, A [Institute of Physics, National Academy of Sciences, Minsk (Belarus); Bohm, C [Stockholm University, Stockholm (Sweden); Boldea, V [National Institute for Physics and Nuclear Engineering, Bucharest (Romania); Bosman, M [Institut de Fisica d' Altes Energies, Universitat Autonoma de Barcelona, Barcelona (Spain); Bromberg, C [Michigan State University, East Lansing, Michigan (United States); Budagov, J [JINR, Dubna (Russian Federation); Burckhart-Chromek, D [CERN, Geneva (Switzerland); Caprini, M [National Institute for Physics and Nuclear Engineering, Bucharest (Romania)

    2009-07-21

    We report test beam studies of 11% of the production ATLAS Tile Calorimeter modules. The modules were equipped with production front-end electronics and all the calibration systems planned for the final detector. The studies used muon, electron and hadron beams ranging in energy from 3 to 350 GeV. Two independent studies showed that the light yield of the calorimeter was {approx}70pe/GeV, exceeding the design goal by 40%. Electron beams provided a calibration of the modules at the electromagnetic energy scale. Over 200 calorimeter cells the variation of the response was 2.4%. The linearity with energy was also measured. Muon beams provided an intercalibration of the response of all calorimeter cells. The response to muons entering in the ATLAS projective geometry showed an RMS variation of 2.5% for 91 measurements over a range of rapidities and modules. The mean response to hadrons of fixed energy had an RMS variation of 1.4% for the modules and projective angles studied. The response to hadrons normalized to incident beam energy showed an 8% increase between 10 and 350 GeV, fully consistent with expectations for a noncompensating calorimeter. The measured energy resolution for hadrons of {sigma}/E=52.9%/{radical}(E)+5.7% was also consistent with expectations. Other auxiliary studies were made of saturation recovery of the readout system, the time resolution of the calorimeter and the performance of the trigger signals from the calorimeter.

  19. The convergence of quantum-dot-mediated fluorescence resonance energy transfer and microfluidics for monitoring DNA polyplex self-assembly in real time

    International Nuclear Information System (INIS)

    Ho Yiping; Wang, T-H; Chen, Hunter H; Leong, Kam W

    2009-01-01

    We present a novel convergence of quantum-dot-mediated fluorescence resonance energy transfer (QD-FRET) and microfluidics, through which molecular interactions were precisely controlled and monitored using highly sensitive quantum-dot-mediated FRET. We demonstrate its potential in studying the kinetics of self-assembly of DNA polyplexes under laminar flow in real time with millisecond resolution. The integration of nanophotonics and microfluidics offers a powerful tool for elucidating the formation of polyelectrolyte polyplexes, which is expected to provide better control and synthesis of uniform and customizable polyplexes for future nucleic acid-based therapeutics.

  20. Optical detection in microfluidic systems

    DEFF Research Database (Denmark)

    Mogensen, Klaus Bo; Kutter, Jörg Peter

    2009-01-01

    Optical detection schemes continue to be favoured for measurements in microfluidic systems. A selection of the latest progress mainly within the last two years is critically reviewed. Emphasis is on integrated solutions, such as planar waveguides, coupling schemes to the outside world, evanescent...... to ease commercialisation of the devices. This work will hopefully result in more commercial products that benefit from integrated optics, because the impact on commercial devices so far has been modest....

  1. Microfluidic Devices for Blood Fractionation

    OpenAIRE

    Hou, Han Wei; Bhagat, Ali Asgar S.; Lee, Wong Cheng J.; Huang, Sha; Han, Jongyoon; Lim, Chwee Teck

    2011-01-01

    Blood, a complex biological fluid, comprises 45% cellular components suspended in protein rich plasma. These different hematologic components perform distinct functions in vivo and thus the ability to efficiently fractionate blood into its individual components has innumerable applications in both clinical diagnosis and biological research. Yet, processing blood is not trivial. In the past decade, a flurry of new microfluidic based technologies has emerged to address this compelling problem. ...

  2. Bistable diverter valve in microfluidics

    Czech Academy of Sciences Publication Activity Database

    Tesař, Václav; Bandulasena, H.C.H.

    2011-01-01

    Roč. 50, č. 5 (2011), s. 1225-1233 ISSN 0723-4864 R&D Projects: GA ČR GA101/07/1499; GA AV ČR IAA200760705 Institutional research plan: CEZ:AV0Z20760514 Keywords : fluidics * bistable diverter valves * pressure-driven microfluidics Subject RIV: BK - Fluid Dynamics Impact factor: 1.735, year: 2011 http://www.springerlink.com/content/x4907p1908151522/

  3. Microfluidic Devices for Blood Fractionation

    Directory of Open Access Journals (Sweden)

    Chwee Teck Lim

    2011-07-01

    Full Text Available Blood, a complex biological fluid, comprises 45% cellular components suspended in protein rich plasma. These different hematologic components perform distinct functions in vivo and thus the ability to efficiently fractionate blood into its individual components has innumerable applications in both clinical diagnosis and biological research. Yet, processing blood is not trivial. In the past decade, a flurry of new microfluidic based technologies has emerged to address this compelling problem. Microfluidics is an attractive solution for this application leveraging its numerous advantages to process clinical blood samples. This paper reviews the various microfluidic approaches realized to successfully fractionate one or more blood components. Techniques to separate plasma from hematologic cellular components as well as isolating blood cells of interest including certain rare cells are discussed. Comparisons based on common separation metrics including efficiency (sensitivity, purity (selectivity, and throughput will be presented. Finally, we will provide insights into the challenges associated with blood-based separation systems towards realizing true point-of-care (POC devices and provide future perspectives.

  4. New tools for the simulation and design of calorimeters

    International Nuclear Information System (INIS)

    Womersley, W.J.

    1989-01-01

    Two new approaches to the simulation and design of large hermetic calorimeters are presented. Firstly, the Shower Library scheme used in the fast generation of showers in the Monte Carlo of the calorimeter for the D-Zero experiment at the Fermilab Tevatron is described. Secondly, a tool for the design future calorimeters is described, which can be integrated with a computer aided design system to give engineering designers an immediate idea of the relative physics capabilities of different geometries. 9 refs., 6 figs., 1 tab

  5. Discussion on the electromagnetic calorimeters of ATLAS and CMS

    Energy Technology Data Exchange (ETDEWEB)

    Aleksa, Martin, E-mail: martin.aleksa@cern.ch [CERN, Geneva 23, 1211 Geneva (Switzerland); Diemoz, Marcella [INFN Roma, Piazzale Aldo Moro 2, 00185 Rome (Italy)

    2013-12-21

    This document summarizes a discussion on the electromagnetic calorimeters of ATLAS and CMS, two experiments at the CERN Large Hadron Collider (LHC), that took place at the 13th Vienna Conference on Instrumentation in February 2013. During the discussion each electromagnetic calorimeter and its performance was described in response to ten questions chosen to cover a wide range from the design and construction of the calorimeters over the calibration and performance to their role in the discovery of the Higgs boson and upgrade plans.

  6. Performance of a highly segmented scintillating fibres electromagnetic calorimeter

    International Nuclear Information System (INIS)

    Asmone, A.; Bertino, M.; Bini, C.; De Zorzi, G.; Diambrini Palazzi, G.; Di Cosimo, G.; Di Domenico, A.; Garufi, F.; Gauzzi, P.; Zanello, D.

    1993-01-01

    A prototype of scintillating fibres electromagnetic calorimeter has been constructed and tested with 2, 4 and 8 GeV electron beams at the CERN PS. The calorimeter modules consist of a Bi-Pb-Sn alloy and scintillating fibres. The fibres are parallel to the modules longer axis, and nearly parallel to the incident electrons direction. The calorimeter has two different segmentation regions of 24x24 mm 2 and 8x24 mm 2 cross area respectively. Results on energy and impact point space resolution are obtained and compared for the two different granularities. (orig.)

  7. Performance of CREAM Calorimeter Results of Beam Tests

    CERN Document Server

    Ahn, H S; Beatty, J J; Bigongiari, G; Castellina, A; Childers, J T; Conklin, N B; Coutu, S; Duvernois, M A; Ganel, O; Han, J H; Hyun, H J; Kang, T G; Kim, H J; Kim, K C; Kim, M Y; Kim, T; Kim, Y J; Lee, J K; Lee, M H; Lutz, L; Maestro, P; Malinine, A; Marrocchesi, P S; Mognet, S I; Nam, S W; Nutter, S; Park, N H; Park, H; Seo, E S; Sina, R; Syed, S; Song, C; Swordy, S; Wu, J; Yang, J; Zhang, H Q; Zei, R; Zinn, S Y

    2005-01-01

    The Cosmic Ray Energetics And Mass (CREAM), a balloon-borne experiment, is under preparation for a flight in Antarctica at the end of 2004. CREAM is planned to measure the energy spectrum and composition of cosmic rays directly at energies between 1 TeV and 1000 TeV. Incident particle energies will be measured by a transition radiation detector and a sampling calorimeter. The calorimeter was constructed at the University of Maryland and tested at CERN in 2003. Performance of the calorimeter during the beam tests is reported.

  8. Energy Resolution Performance of the CMS Electromagnetic Calorimeter

    CERN Document Server

    Adzic, Petar; Almeida, Carlos; Almeida, Nuno; Anagnostou, Georgios; Anfreville, Marc; Anicin, Ivan; Antunovic, Zeljko; Auffray, Etiennette; Baccaro, Stefania; Baffioni, Stephanie; Barney, David; Barone, Luciano; Barrillon, Pierre; Bartoloni, Alessandro; Beauceron, Stephanie; Beaudette, Florian; Bell, Ken W; Benetta, Robert; Bercher, Michel; Berthon, Ursula; Betev, Botjo; Beuselinck, Raymond; Bhardwaj, Ashutosh; Biino, Cristina; Bimbot, Stephane; Blaha, Jan; Bloch, Philippe; Blyth, Simon; Bordalo, Paula; Bornheim, Adolf; Bourotte, Jean; Britton1, D; Brown, Robert M; Brunelière, Renaud; Busson, Philippe; Camporesi, Tiziano; Cartiglia, Nicolo; Cavallari, Francesca; Cerutti, Muriel; Chamont, David; Chang, Paoti; Chang, You-Hao; Charlot, Claude; Chatterji, Sudeep; Chen, E Augustine; Chipaux, Rémi; Choudhary, Brajesh C; Cockerill, David J A; Collard, Caroline; Combaret, Christophe; Cossutti, Fabio; Costantini, Silvia; Da Silva, J C; Dafinei, Ioan; Daskalakis, Georgios; Davatz, Giovanna; Debraine, Alain; Decotigny, David; De Min, Alberto; Deiters, Konrad; Dejardin, Marc; Della Negra, Rodolphe; Della Ricca, Giuseppe; Depasse, Pierre; Descamp, J; Dewhirst, Guy; Dhawan, Satish; Diemoz, Marcella; Dissertori, Günther; Dittmar, Michael; Djambazov, Lubomir; Dobrzynski, Ludwik; Drndarevic, Snezana; Dupanloup, Michel; Dzelalija, Mile; Ehlers, Jan; El-Mamouni, H; Peisert, Anna; Evangelou, Ioannis; Fabbro, Bernard; Faure, Jean-Louis; Fay, Jean; Ferri, Federico; Flower, Paul S; Franzoni, Giovanni; Funk, Wolfgang; Gaillac, Anne-Marie; Gargiulo, Corrado; Gascon-Shotkin, S; Geerebaert, Yannick; Gentit, François-Xavier; Ghezzi, Alessio; Gilly, Jean; Giolo-Nicollerat, Anne-Sylvie; Givernaud, Alain; Gninenko, Sergei; Go, Apollo; Godinovic, Nikola; Golubev, Nikolai; Golutvin, Igor; Gómez-Reino, Robert; Govoni, Pietro; Grahl1, J; Gras1, P; Greenhalgh, Justin; Guillaud, Jean-Paul; Haguenauer, Maurice; Hamel-de-Montechenault, G; Hansen, Magnus; Heath, Helen F; AHill, J; Hobson, Peter R; Holmes, Daniel; Holzner, André; Hou, George Wei-Shu; Ille, Bernard; Ingram, Quentin; Jain, Adarsh; Jarry, Patrick; Jauffret, C; Jha, Manoj; Karar, Akli; Kataria, Sushil Kumar; Katchanov, V A; Kennedy, Bruce W; Kloukinas, Kostas; Kokkas, Panagiotis; Korjik, M; Krasnikov, Nikolai; Krpic, Dragomir; Kyriakis, Aristotelis; Lebeau, Michel; Lecomte, Pierre; Lecoq, Paul; Lemaire, Marie-Claude; Lethuillier, Morgan; Lin, Willis; Lintern, A L; Lister, Alison; Litvin, V; Locci, Elizabeth; Lodge, Anthony B; Longo, Egidio; Loukas, Demetrios; Luckey, D; Lustermann, Werner; Lynch, Clare; MacKay, Catherine Kirsty; Malberti, Martina; Maletic, Dimitrije; Mandjavidze, Irakli; Manthos, Nikolaos; Markou, Athanasios; Mathez, Hervé; Mathieu, Antoine; Matveev, Viktor; Maurelli, Georges; Menichetti, Ezio; Meridiani, Paolo; Milenovic, Predrag; Milleret, Gérard; Miné, Philippe; Mur, Michel; Musienko, Yuri; Nardulli, Alessandro; Nash, Jordan; Neal, Homer; Nédélec, Patrick; Negri, Pietro; Nessi-Tedaldi, Francesca; Newman26, H B; Nikitenko, Alexander; Obertino, Maria Margherita; Ofierzynski, Radoslaw Adrian; Organtini, Giovanni; Paganini, Pascal; Paganoni, Marco; Papadopoulos, Ioannis; Paramatti, Riccardo; Pastrone, Nadia; Pauss, Felicitas; Poilleux, Patrick; Puljak, Ivica; Pullia, Antonino; Puzovic, Jovan; Ragazzi, Stefano; Ramos, Sergio; Rahatlou, Shahram; Rander, John; Ranjan, Kirti; Ravat, Olivier; Raymond, M; Razis, Panos A; Redaelli, Nicola; Renker, Dieter; Reucroft, Steve; Reymond, Jean-Marc; Reynaud, Michel; Reynaud, Serge; Romanteau, Thierry; Rondeaux, Françoise; Rosowsky, André; Rovelli, Chiara; Rumerio, Paolo; Rusack, Roger; Rusakov, Sergey V; Ryan, Matthew John; Rykaczewski, Hans; Sakhelashvili, Tariel; Salerno, Roberto; Santos, Marcelino; Seez, Christopher; Semeniouk, Igor; Sharif, Omar; Sharp, Peter; Shepherd-Themistocleous, Claire; Shevchenko, Sergey; Shivpuri, Ram Krishen; Sidiropoulos, Georgios; Sillou, Daniel; Singovsky, Alexander; Sirois, Yves; Sirunyan, Albert M; Smith, Brian; Smith, Vincent J; Sproston, Martin; Suter, Henry; Swain, John; Tabarelli de Fatis, Tommaso; Takahashi, Maiko; Tapper, Robert J; Tcheremoukhine, Alexandre; Teixeira, Isabel; Teixeira, Joao Paulo; Teller, Olivier; Timlin, Claire; ATriantis, F; Troshin, Sergey; Tyurin, Nikolay; Ueno, Koji; Uzunian, Andrey; Varela, Joao; Vaz-Cardoso, N; Verrecchia, Patrice; Vichoudis, Paschalis; Vigano, S; Viertel, Gert; Virdee, Tejinder; Vlassov, E; Wang, Minzu; Weinstein, Alan; Williams, Jennifer C; Yaselli, Ignacio; Zabi, Alexandre; Zamiatin, Nikolai; Zelepoukine, Serguei; Zeller, Michael E; Zhang, Lin; Zhang, Yawei; Zhu, Kejun; Zhu, Ren-Yuan

    2006-01-01

    The energy resolution performance of the CMS lead tungstate crystal electromagnetic calorimeter is presented. Measurements were made with an electron beam using a fully equipped supermodule of the calorimeter barrel. Results are given both for electrons incident on the centre of crystals and for electrons distributed uniformly over the calorimeter surface. The electron energy is reconstructed in matrices of 3 times 3 or 5 times 5 crystals centred on the crystal containing the maximum energy. Corrections for variations in the shower containment are applied in the case of uniform incidence. The resolution measured is consistent with the design goals.

  9. The Small angle TIle Calorimeter project in DELPHI

    International Nuclear Information System (INIS)

    Alvsvaag, S.J.; Maeland, O.A.; Klovning, A.

    1995-01-01

    The new Small Angle TIle Calorimeter (STIC) covers the forward regions in DELPHI. The main motivation for its construction was to achieve a systematic error of 0.1% on the luminosity determination. This detector consists of a ''shashlik'' type calorimeter, equipped with two planes of silicon pad detectors placed respectively after 4 and 7.4 radiation lengths. A veto counter, composed of two scintillator planes, covers the front of the calorimeter to allow e-γ separation and to provide a neutral energy trigger.The physics motivations for this project, results from extensive testbeam measurements and the performance during the 1994 LEP run are reported here. (orig.)

  10. The small angle tile calorimeter in the DELPHI experiment

    International Nuclear Information System (INIS)

    Alvsvaag, S.J.; Bari, M.; Barreira, G.; Benvenuti, A.C.; Bigi, M.; Bonesini, M.; Bozzo, M.; Camporesi, T.; Carling, H.; Cassio, V.; Castellani, L.; Cereseto, R.; Chignoli, F.; Della Ricca, G.; Dharmasiri, D.R.; Santo, M.C. Espirito; Falk, E.; Fenyuk, A.; Ferrari, P.; Gamba, D.; Giordano, V.; Gouz, Yu.; Guerzoni, M.; Gumenyuk, S.; Hedberg, V.; Jarlskog, G.; Karyukhin, A.; Klovning, A.; Konoplyannikov, A.; Kronkvist, I.; Lanceri, L.; Leoni, R.; Maeland, O.A.; Maio, A.; Mazza, R.; Migliore, E.; Navarria, F.L.; Negri, P.; Nossum, B.; Obraztsov, V.; Onofre, A.; Paganoni, M.; Pegoraro, M.; Peralta, L.; Petrovykh, L.; Pimenta, M.; Poropat, P.; Prest, M.; Read, A.L.; Romero, A.; Shalanda, N.; Simonetti, L.; Skaali, T.B.; Stugu, B.; Terranova, F.; Tome, B.; Torassa, E.; Trapani, P.P.; Verardi, M.G.; Vallazza, E.; Vlasov, E.; Zaitsev, A.

    1999-01-01

    The Small angle TIle Calorimeter (STIC) provides calorimetric coverage in the very forward region of the DELPHI experiment at the CERN LEP collider. The structure of the calorimeters, built with a so-called 'shashlik' technique, gives a perfectly hermetic calorimeter and still allows for the insertion of tracking detectors within the sampling structure to measure the direction of the showering particle. A charged-particle veto system, composed of two scintillator layers, makes it possible to trigger on single photon events and provides e-γ separation. Results are presented from the extensive studies of these detectors in the CERN testbeams prior of installation and of the detector performance at LEP

  11. Proposal for a level 0 calorimeter trigger system for LHCb

    CERN Document Server

    Bertin, A; Capponi, M; D'Antone, I; De Castro, S; Donà, R; Galli, D; Giacobbe, B; Marconi, U; Massa, I; Piccinini, M; Poli, M; Semprini-Cesari, N; Spighi, R; Vecchi, S; Villa, M; Vitale, A; Zoccoli, A; Zoccoli, Antonio

    1999-01-01

    In this note we present a complete system for the Level-0 LHCb calorimeter triggers. The system is derived from the electromagnetic calorimeter pre-trigger developed for the HERA-B experiment. The proposed system follows closely the Level-0 trigger algorithms presented in the LHCb Technical Proposal based on an electromagnetic and hadronic showers analysis performed on 3x3 calorimeter matrix. The general architecture presented is completely synchronous and quite flexible to allow adaptation to further improvements on the Level-0 trigger algorithms.

  12. Measurements with the Hungarian Heat-Flow Calorimeter

    International Nuclear Information System (INIS)

    Bod, L.

    1970-01-01

    This calorimeter, like the others, consists of three essential parts: 1) the calorimetric sample; the radiation energy absorbed therein is to be determined; 2) the jacket; a well defined environment which includes the calorimetric sample; 3) the heat transfer medium, separating the former two. The measurement with this calorimeter consists of the determination of the equilibrium temperature difference between the calorimetric sample and the jacket of the calorimeter in the radiation field. From this the radiation energy absorbed in the calorimetric sample can be evaluated

  13. Simulation of secondary emission calorimeter for future colliders

    Science.gov (United States)

    Yetkin, E. A.; Yetkin, T.; Ozok, F.; Iren, E.; Erduran, M. N.

    2018-03-01

    We present updated results from a simulation study of a conceptual sampling electromagnetic calorimeter based on secondary electron emission process. We implemented the secondary electron emission process in Geant4 as a user physics list and produced the energy spectrum and yield of secondary electrons. The energy resolution of the SEE calorimeter was σ/E = (41%) GeV1/2/√E and the response linearity to electromagnetic showers was to within 1.5%. The simulation results were also compared with a traditional scintillator calorimeter.

  14. Radioactively induced noise in gas-sampling uranium calorimeters

    International Nuclear Information System (INIS)

    Gordon, H.A.; Rehak, P.

    1982-01-01

    The signal induced by radioactivity of a U 238 absorber in a cell of a gas-sampling uranium calorimeter was studied. By means of Campbell's theorem, the levels of the radioactively induced noise in uranium gas-sampling calorimeters was calculated. It was shown that in order to obtain similar radioactive noise performance as U-liquid argon or U-scintillator combinations, the α-particles from the uranium must be stopped before entering the sensing volume of gas-uranium calorimeters

  15. Development of real-time low energy electron calorimeter

    International Nuclear Information System (INIS)

    Noriah Mod Ali; Smith, F.A.

    1999-01-01

    A low energy electron beam calorimeter with a thin film window has been fabricated to facilitate a reliable method of dose assessment for electron beam energies down to 200 keV. The system was designed to incorporate a data-logger in order that it could be used on the self-shielded 200 keV facility at MINT. In use, the calorimeter started logging temperature a short time before it passed under the beam and it continued taking data until well after the end of the irradiation. Data could be retrieved at any time after the calorimeter had emerged from the irradiator

  16. Hadron calorimeter module prototype for baryonic matter studies at Nuclotron

    OpenAIRE

    Gavrishchuk, O. P.; Ladygin, V. P.; Petukhov, Yu. P.; Sychkov, S. Ya

    2014-01-01

    The prototype of the hadron calorimeter module consisting of 66 scintillator/lead layers with the 15x15 cm^2 cross section and 5 nuclear interaction lengths has been designed and produced for the zero degree calorimeter of the BM@N experiment. The prototype has been tested with high energy muon beam of the U-70 accelerator at IHEP. The results of the beam test for different types of photo multipliers and light guides are presented. The results of the Monte-Carlo simulation of the calorimeter ...

  17. ATLAS Liquid Argon Calorimeter Module Zero

    CERN Multimedia

    1993-01-01

    This module was built and tested with beam to validate the ATLAS electromagnetic calorimeter design. One original design feature is the folding. 10 000 lead plates and electrodes are folded into an accordion shape and immersed in liquid argon. As they cross the folds, particles are slowed down by the lead. As they collide with the lead atoms, electrons and photons are ejected. There is a knock-on effect and as they continue on into the argon, a whole shower is produced. The electrodes collect up all the electrons and this signal gives a measurement of the energy of the initial particle. The M0 was fabricated by French institutes (LAL, LAPP, Saclay, Jussieu) in the years 1993-1994. It was tested in the H6/H8 beam lines in 1994, leading to the Technical Design Report in 1996.

  18. Electromagnetic Calorimeter Calibration with $\\pi^{0}$

    CERN Multimedia

    Puig Navarro, A

    2009-01-01

    Several methods can be used in order to achieve precise calibration of the LHCb Electromagnetic Calorimeter (ECAL) once reasonable cell equalization has been reached. At low transverse energy, the standard calibration procedure is an iterative method based on the fit of the $\\gamma\\gamma$ invariant mass distribution for each cell of the decay $\\pi^{0}\\to\\gamma\\gamma$ with resolved photons. A new technique for generating the combinatorial background of such decays directly from data has been developed. Knowledge of the background could allow an alternative calibration method based on a event by event fit of the same $\\gamma\\gamma$ invariant mass distribution where contributions from groups of cells are considered in a single fit. The background generation procedure and this possible new calibration method are presented in this poster, in addition to an overview of the LHCb Calorimetry system and ECAL calibration techniques.

  19. Calorimeter Simulation with Hadrons in CMS

    Energy Technology Data Exchange (ETDEWEB)

    Piperov, Stefan; /Sofiya, Inst. Nucl. Res. /Fermilab

    2008-11-01

    CMS is using Geant4 to simulate the detector setup for the forthcoming data from the LHC. Validation of physics processes inside Geant4 is a major concern in view of getting a proper description of jets and missing energy for signal and background events. This is done by carrying out an extensive studies with test beam using the prototypes or real detector modules of the CMS calorimeter. These data are matched with Geant4 predictions using the same framework that is used for the entire CMS detector. Tuning of the Geant4 models is carried out and steps to be used in reproducing detector signals are defined in view of measurements of energy response, energy resolution, transverse and longitudinal shower profiles for a variety of hadron beams over a broad energy spectrum between 2 to 300 GeV/c. The tuned Monte Carlo predictions match many of these measurements within systematic uncertainties.

  20. Tests of gas sampling electromagnetic shower calorimeter

    International Nuclear Information System (INIS)

    Barbaro-Galtieri, A.; Carithers, W.; Day, C.; Johnson, K.J.; Wenzel, W.A.; Videau, H.

    1983-01-01

    An electromagnetic shower gas-sampling calorimeter has been tested in both Geiger and proportional discharge modes for incident electron energies in the range 0.125-16 GeV. The 0.2 radiation length-thick layers were lead-fiberglass laminates with cathode strips normal to the sense wires. The 5x10 mm 2 Geiger cells were formed with uniformly spaced nylon fibers perpendicular to the wires. Proportional mode measurements were carried out in the pressure range 1-10 atm. A Monte Carlo simulation is in good agreement with measured shower characteristics and has been used to predict the behavior for oblique of incidence and for various Geiger cell dimensions. (orig.)

  1. Liquid xenon/krypton scintillation calorimeter

    International Nuclear Information System (INIS)

    Akimov, D.Yu.; Bolozdynya, A.I.; Brastilov, A.D.

    1994-01-01

    A scintillating LXe/LKr electromagnetic calorimeter has been built at the ITEP and tested at the BATES (MIT) accelerator. The detector consists of PMT matrix and 45 light collecting cells made of aluminized 50 microns Mylar partially covered with p-terphenyl as a wavelength-shifter. Each pyramidal cell has (2.1 x 2.1) x 40 x (4.15 x 4.15) cm dimensions and is viewed by FEU-85 glass-window photomultiplier. The detector has been exposed at 106-348 MeV electron beam. The energy resolution σ E /E ≅ 5% √ E at 100 - 350 MeV range in LXe, the coordinate resolution τ x ≅ 0.7 cm, the time resolution for single cell ≅ 0.6 ns have been obtained. Possible ways to improve energy resolution are discussed. 8 refs., 15 figs

  2. The UA1 upgrade calorimeter trigger processor

    International Nuclear Information System (INIS)

    Bains, M.; Charleton, D.; Ellis, N.; Garvey, J.; Gregory, J.; Jimack, M.P.; Jovanovic, P.; Kenyon, I.R.; Baird, S.A.; Campbell, D.; Cawthraw, M.; Coughlan, J.; Flynn, P.; Galagedera, S.; Grayer, G.; Halsall, R.; Shah, T.P.; Stephens, R.; Biddulph, P.; Eisenhandler, E.; Fensome, I.F.; Landon, M.; Robinson, D.; Oliver, J.; Sumorok, K.

    1990-01-01

    The increased luminosity of the improved CERN Collider and the more subtle signals of second-generation collider physics demand increasingly sophisticated triggering. We have built a new first-level trigger processor designed to use the excellent granularity of the UA1 upgrade calorimeter. This device is entirely digital and handles events in 1.5 μs, thus introducing no dead time. Its most novel feature is fast two-dimensional electromagnetic cluster-finding with the possibility of demanding an isolated shower of limited penetration. The processor allows multiple combinations of triggers on electromagnetic showers, hadronic jets and energy sums, including a total-energy veto of multiple interactions and a full vector sum of missing transverse energy. This hard-wired processor is about five times more powerful than its predecessor, and makes extensive use of pipelining techniques. It was used extensively in the 1988 and 1989 runs of the CERN Collider. (orig.)

  3. The UA1 upgrade calorimeter trigger processor

    International Nuclear Information System (INIS)

    Bains, N.; Baird, S.A.; Biddulph, P.

    1990-01-01

    The increased luminosity of the improved CERN Collider and the more subtle signals of second-generation collider physics demand increasingly sophisticated triggering. We have built a new first-level trigger processor designed to use the excellent granularity of the UA1 upgrade calorimeter. This device is entirely digital and handles events in 1.5 μs, thus introducing no deadtime. Its most novel feature is fast two-dimensional electromagnetic cluster-finding with the possibility of demanding an isolated shower of limited penetration. The processor allows multiple combinations of triggers on electromagnetic showers, hadronic jets and energy sums, including a total-energy veto of multiple interactions and a full vector sum of missing transverse energy. This hard-wired processor is about five times more powerful than its predecessor, and makes extensive use of pipelining techniques. It was used extensively in the 1988 and 1989 runs of the CERN Collider. (author)

  4. Muon Detection Based on a Hadronic Calorimeter

    CERN Document Server

    Ciodaro, Thiago; Abreu, R; Achenbach, R; Adragna, P; Aharrouche, M; Aielli, G; Al-Shabibi, A; Aleksandrov, I; Alexandrov, E; Aloisio, A; Alviggi, M G; Amorim, A; Amram, N; Andrei, V; Anduaga, X; Angelaszek, D; Anjos, N; Annovi, A; Antonelli, S; Anulli, F; Apolle, R; Aracena, I; Ask, S; Åsman, B; Avolio, G; Baak, M; Backes, M; Backlund, S; Badescu, E; Baines, J; Ballestrero, S; Banerjee, S; Bansil, H S; Barnett, B M; Bartoldus, R; Bartsch, V; Batraneanu, S; Battaglia, A; Bauss, B; Beauchemin, P; Beck, H P; Bee, C; Begel, M; Behera, P K; Bell, P; Bell, W H; Bellagamba, L; Bellomo, M; Ben Ami, S; Bendel, M; Benhammou, Y; Benslama, K; Berge, D; Bernius, C; Berry, T; Bianco, M; Biglietti, M; Blair, R E; Bogaerts, A; Bohm, C; Boisvert, V; Bold, T; Bondioli, M; Borer, C; Boscherini, D; Bosman, M; Bossini, E; Boveia, A; Bracinik, J; Brandt, A G; Brawn, I P; Brelier, B; Brenner, R; Bressler, S; Brock, R; Brooks, W K; Brown, G; Brunet, S; Bruni, A; Bruni, G; Bucci, F; Buda, S; Burckhart-Chromek, D; Buscher, V; Buttinger, W; Calvet, S; Camarri, P; Campanelli, M; Canale, V; Canelli, F; Capasso, L; Caprini, M; Caracinha, D; Caramarcu, C; Cardarelli, R; Carlino, G; Casadei, D; Casado, M P; Cattani, G; Cerri, A; Cerrito, L; Chapleau, B; Childers, J T; Chiodini, G; Christidi, I; Ciapetti, G; Cimino, D; Ciobotaru, M; Coccaro, A; Cogan, J; Collins, N J; Conde Muino, P; Conidi, C; Conventi, F; Corradi, M; Corso-Radu, A; Coura Torres, R; Cranmer, K; Crescioli, F; Crone, G; Crupi, R; Cuenca Almenar, C; Cummings, J T; Curtis, C J; Czyczula, Z; Dam, M; Damazio, D; Dao, V; Darlea, G L; Davis, A O; De Asmundis, R; De Pedis, D; De Santo, A; de Seixas, J M; Degenhardt, J; Della Pietra, M; Della Volpe, D; Demers, S; Demirkoz, B; Di Ciaccio, A; Di Mattia, A; Di Nardo, R; Di Simone, A; Diaz, M A; Dietzsch, T A; Dionisi, C; Dobson, E; Dobson, M; dos Anjos, A; Dotti, A; Dova, M T; Drake, G; Dufour, M-A; Dumitru, I; Eckweiler, S; Ehrenfeld, W; Eifert, T; Eisenhandler, E; Ellis, K V; Ellis, N; Emeliyanov, D; Enoque Ferreira de Lima, D; Ermoline, Y; Ernst, J; Etzion, E; Falciano, S; Farrington, S; Farthouat, P; Faulkner, P J W; Fedorko, W; Fellmann, D; Feng, E; Ferrag, S; Ferrari, R; Ferrer, M L; Fiorini, L; Fischer, G; Flowerdew, M J; Fonseca Martin, T; Francis, D; Fratina, S; French, S T; Front, D; Fukunaga, C; Gadomski, S; Garelli, N; Garitaonandia Elejabarrieta, H; Gaudio, G; Gee, C N P; George, S; Giagu, S; Giannetti, P; Gillman, A R; Giorgi, M; Giunta, M; Giusti, P; Goebel, M; Gonçalo, R; Gonzalez Silva, L; Göringer, C; Gorini, B; Gorini, E; Grabowska-Bold, I; Green, B; Groll, M; Guida, A; Guler, H; Haas, S; Hadavand, H; Hadley, D R; Haller, J; Hamilton, A; Hanke, P; Hansen, J R; Hasegawa, S; Hasegawa, Y; Hauser, R; Hayakawa, T; Hayden, D; Head, S; Heim, S; Hellman, S; Henke, M; Hershenhorn, A; Hidvégi, A; Hillert, S; Hillier, S J; Hirayama, S; Hod, N; Hoffmann, D; Hong, T M; Hryn'ova, T; Huston, J; Iacobucci, G; Igonkina, O; Ikeno, M; Ilchenko, Y; Ishikawa, A; Ishino, M; Iwasaki, H; Izzo, V; Jez, P; Jimenez Otero, S; Johansen, M; Johns, K; Jones, G; Joos, M; Kadlecik, P; Kajomovitz, E; Kanaya, N; Kanega, F; Kanno, T; Kapliy, A; Kaushik, V; Kawagoe, K; Kawamoto, T; Kazarov, A; Kehoe, R; Kessoku, K; Khomich, A; Khoriauli, G; Kieft, G; Kirk, J; Klemetti, M; Klofver, P; Klous, S; Kluge, E-E; Kobayashi, T; Koeneke, K; Koletsou, I; Koll, J D; Kolos, S; Kono, T; Konoplich, R; Konstantinidis, N; Korcyl, K; Kordas, K; Kotov, V; Kowalewski, R V; Krasznahorkay, A; Kraus, J; Kreisel, A; Kubota, T; Kugel, A; Kunkle, J; Kurashige, H; Kuze, M; Kwee, R; Laforge, B; Landon, M; Lane, J; Lankford, A J; Laranjeira Lima, S M; Larner, A; Leahu, L; Lehmann Miotto, G; Lei, X; Lellouch, D; Levinson, L; Li, S; Liberti, B; Lilley, J N; Linnemann, J T; Lipeles, E; Lohse, T; Losada, M; Lowe, A; Luci, C; Luminari, L; Lundberg, J; Lupu, N; Machado Miguéns, J; Mackeprang, R; Maettig, S; Magnoni, L; Maiani, C; Maltrana, D; Mangeard, P-S; Männer, R; Mapelli, L; Marchese, F; Marino, C; Martin, B; Martin, B T; Martin, T; Martyniuk, A; Marzano, F; Masik, J; Mastrandrea, P; Matsushita, T; McCarn, A; Mechnich, J; Medinnis, M; Meier, K; Melachrinos, C; Mendoza Nava, L M; Merola, L; Messina, A; Meyer, C P; Middleton, R P; Mikenberg, G; Mills, C M; Mincer, A; Mineev, M; Misiejuk, A; Moa, T; Moenig, K; Monk, J; Monticelli, F; Mora Herrera, C; Morettini, P; Morris, J D; Müller, F; Munwes, Y; Murillo Garcia, R; Nagano, K; Nagasaka, Y; Navarro, G A; Negri, A; Nelson, S; Nemethy, P; Neubauer, M S; Neusiedl, A; Newman, P; Nisati, A; Nomoto, H; Nozaki, M; Nozicka, M; Nurse, E; Ochando, C; Ochi, A; Oda, S; Oh, A; Ohm, C; Okumura, Y; Olivito, D; Omachi, C; Osculati, B; Oshita, H; Ospanov, R; Owen, M A; Özcan, V E; Ozone, K; Padilla, C; Panes, B; Panikashvili, N; Paramonov, A; Parodi, F; Pasqualucci, E; Pastore, F; Patricelli, S; Pauly, T; Perera, V J O; Perez, E; Petcu, M; Petersen, B A; Petersen, J; Petrolo, E; Phan, A; Piegaia, R; Pilkington, A; Pinder, A; Poddar, S; Polini, A; Pope, B G; Potter, C T; Primavera, M; Prokoshin, F; Ptacek, E; Qian, W; Quinonez, F; Rajagopalan, S; Ramos Dos Santos Neves, R; Reinherz-Aronis, E; Reinsch, A; Renkel, P; Rescigno, M; Rieke, S; Riu, I; Robertson, S H; Robinson, M; Rodriguez, D; Roich, A; Romeo, G; Romero, R; Roos, L; Ruiz Martinez, A; Ryabov, Y; Ryan, P; Saavedra, A; Safai Tehrani, F; Sakamoto, H; Salamanna, G; Salamon, A; Saland, J; Salnikov, A; Salvatore, F; Sankey, D P C; Santamarina, C; Santonico, R; Sarkisyan-Grinbaum, E; Sasaki, O; Savu, D; Scannicchio, D A; Schäfer, U; Scharf, V L; Scheirich, D; Schiavi, C; Schlereth, J; Schmitt, K; Schroder, C; Schroer, N; Schultz-Coulon, H-C; Schwienhorst, R; Sekhniaidze, G; Sfyrla, A; Shamim, M; Sherman, D; Shimojima, M; Shochet, M; Shooltz, D; Sidoti, A; Silbert, O; Silverstein, S; Sinev, N; Siragusa, G; Sivoklokov, S; Sjoen, R; Sjölin, J; Slagle, K; Sloper, J E; Smith, B C; Soffer, A; Soloviev, I; Spagnolo, S; Spiwoks, R; Staley, R J; Stamen, R; Stancu, S; Steinberg, P; Stelzer, J; Stockton, M C; Straessner, A; Strauss, E A; Strom, D; Su, D; Sugaya, Y; Sugimoto, T; Sushkov, S; Sutton, M R; Suzuki, Y; Taffard, A; Taiblum, N; Takahashi, Y; Takeda, H; Takeshita, T; Tamsett, M; Tan, C L A; Tanaka, S; Tapprogge, S; Tarem, S; Tarem, Z; Taylor, C; Teixeira-Dias, P; Thomas, J P; Thompson, P D; Thomson, M A; Tokushuku, K; Tollefson, K; Tomoto, M; Topfel, C; Torrence, E; Touchard, F; Traynor, D; Tremblet, L; Tricoli, A; Tripiana, M; Triplett, N; True, P; Tsiakiris, M; Tsuno, S; Tuggle, J; Ünel, G; Urquijo, P; Urrejola, P; Usai, G; Vachon, B; Vallecorsa, S; Valsan, L; Vandelli, W; Vari, R; Vaz Gil Lopes, L; Veneziano, S; Ventura, A; Venturi, N; Vercesi, V; Vermeulen, J C; Volpi, G; Vorwerk, V; Wagner, P; Wang, M; Warburton, A; Watkins, P M; Watson, A T; Watson, M; Weber, P; Weidberg, A R; Wengler, T; Werner, P; Werth, M; Wessels, M; White, M; Whiteson, D; Wickens, F J; Wiedenmann, W; Wielers, M; Winklmeier, F; Woods, K S; Wu, S-L; Wu, X; Xaplanteris Karampatsos, L; Xella, S; Yakovlev, A; Yamazaki, Y; Yang, U; Yasu, Y; Yuan, L; Zaitsev, A; Zanello, L; Zhang, H; Zhang, J; Zhao, L; Zobernig, H; zur Nedden, M

    2010-01-01

    The TileCal hadronic calorimeter provides a muon signal which can be used to assist in muon tagging at the ATLAS level-one trigger. Originally, the muon signal was conceived to be combined with the RPC trigger in order to reduce unforeseen high trigger rates due to cavern background. Nevertheless, the combined trigger cannot significantly deteriorate the muon detection performance at the barrel region. This paper presents preliminary studies concerning the impact in muon identification at the ATLAS level-one trigger, through the use of Monte Carlo simulations with single muons with 40 GeV/c momentum. Further, different trigger scenarios were proposed, together with an approach for matching both TileCal and RPC geometries.

  5. Trigger circuits for the PHENIX electromagnetic calorimeter

    International Nuclear Information System (INIS)

    Frank, S.S.; Britton, C.L. Jr.; Winterberg, A.L.; Young, G.R.

    1997-11-01

    Monolithic and discrete circuits have been developed to provide trigger signals for the PHENIX electromagnetic calorimeter detector. These trigger circuits are deadtimeless and create overlapping 4 by 4 energy sums, a cosmic muon trigger, and a 144 channel energy sum. The front end electronics of the PHENIX system sample the energy and timing channels at each bunch crossing (BC) but it is not known immediately if this data is of interest. The information from the trigger circuits is used to determine if the data collected is of interest and should be digitized and stored or discarded. This paper presents details of the design, issues affecting circuit performance, characterization of prototypes fabricated in 1.2 microm Orbit CMOS, and integration of the circuits into the EMCal electronics system

  6. Microfluidic acoustophoretic force based low-concentration oil separation and detection from the environment.

    Science.gov (United States)

    Wang, Han; Liu, Zhongzheng; Kim, Sungman; Koo, Chiwan; Cho, Younghak; Jang, Dong-Young; Kim, Yong-Joe; Han, Arum

    2014-03-07

    Detecting and quantifying extremely low concentrations of oil from the environment have broad applications in oil spill monitoring in ocean and coastal areas as well as in oil leakage monitoring on land. Currently available methods for low-concentration oil detection are bulky or costly with limited sensitivities. Thus they are difficult to be used as portable and field-deployable detectors in the case of oil spills or for monitoring the long-term effects of dispersed oil on marine and coastal ecosystems. Here, we present a low-concentration oil droplet trapping and detection microfluidic system based on the acoustophoresis phenomenon where oil droplets in water having a negative acoustic contrast factor move towards acoustic pressure anti-nodes. By trapping oil droplets from water samples flowing through a microfluidic channel, even very low concentrations of oil droplets can be concentrated to a detectable level for further analyses, which is a significant improvement over currently available oil detection systems. Oil droplets in water were successfully trapped and accumulated in a circular acoustophoretic trapping chamber of the microfluidic device and detected using a custom-built compact fluorescent detector based on the natural fluorescence of the trapped crude oil droplets. After the on-line detection, crude oil droplets released from the trapping chamber were successfully separated into a collection outlet by acoustophoretic force for further off-chip analyses. The developed microfluidic system provides a new way of trapping, detecting, and separating low-concentration crude oil from environmental water samples and holds promise as a low-cost field-deployable oil detector with extremely high sensitivity. The microfluidic system and operation principle are expected to be utilized in a wide range of applications where separating, concentrating, and detecting small particles having a negative acoustic contrast factor are required.

  7. Detection methods for centrifugal microfluidic platforms

    DEFF Research Database (Denmark)

    Burger, Robert; Amato, Letizia; Boisen, Anja

    2016-01-01

    Centrifugal microfluidics has attracted much interest from academia as well as industry, since it potentially offers solutions for affordable, user-friendly and portable biosensing. A wide range of so-called fluidic unit operations, e.g. mixing, metering, liquid routing, and particle separation...... for the centrifugal microfluidics platform and cover optical as well as mechanical and electrical detection principles....

  8. Preface book Microfluidics for medical applications

    NARCIS (Netherlands)

    van den Berg, Albert; Segerink, Loes Irene

    2015-01-01

    This book presents an overview of the major microfluidics techniques and platforms used for medicine and medical applications, providing the reader with an overview of the recent developments in this field. It is divided in three parts: (1) tissue and organs on-chip, (2) microfluidics for medicine

  9. Cell Culture Microfluidic Biochips: Experimental Throughput Maximization

    DEFF Research Database (Denmark)

    Minhass, Wajid Hassan; Pop, Paul; Madsen, Jan

    2011-01-01

    Microfluidic biochips offer a promising alternative to a conventional biochemical laboratory, integrating all necessary functionalities on-chip in order to perform biochemical applications. Researchers have started to propose computer-aided design tools for the synthesis of such biochips. Our focus...... metaheuristic for experimental design generation for the cell culture microfluidic biochips, and we have evaluated our approach using multiple experimental setups....

  10. Modular microfluidic system for biological sample preparation

    Science.gov (United States)

    Rose, Klint A.; Mariella, Jr., Raymond P.; Bailey, Christopher G.; Ness, Kevin Dean

    2015-09-29

    A reconfigurable modular microfluidic system for preparation of a biological sample including a series of reconfigurable modules for automated sample preparation adapted to selectively include a) a microfluidic acoustic focusing filter module, b) a dielectrophoresis bacteria filter module, c) a dielectrophoresis virus filter module, d) an isotachophoresis nucleic acid filter module, e) a lyses module, and f) an isotachophoresis-based nucleic acid filter.

  11. Principles, Techniques, and Applications of Tissue Microfluidics

    Science.gov (United States)

    Wade, Lawrence A.; Kartalov, Emil P.; Shibata, Darryl; Taylor, Clive

    2011-01-01

    The principle of tissue microfluidics and its resultant techniques has been applied to cell analysis. Building microfluidics to suit a particular tissue sample would allow the rapid, reliable, inexpensive, highly parallelized, selective extraction of chosen regions of tissue for purposes of further biochemical analysis. Furthermore, the applicability of the techniques ranges beyond the described pathology application. For example, they would also allow the posing and successful answering of new sets of questions in many areas of fundamental research. The proposed integration of microfluidic techniques and tissue slice samples is called "tissue microfluidics" because it molds the microfluidic architectures in accordance with each particular structure of each specific tissue sample. Thus, microfluidics can be built around the tissues, following the tissue structure, or alternatively, the microfluidics can be adapted to the specific geometry of particular tissues. By contrast, the traditional approach is that microfluidic devices are structured in accordance with engineering considerations, while the biological components in applied devices are forced to comply with these engineering presets.

  12. Opportunities for microfluidic technologies in synthetic biology

    OpenAIRE

    Gulati, Shelly; Rouilly, Vincent; Niu, Xize; Chappell, James; Kitney, Richard I.; Edel, Joshua B.; Freemont, Paul S.; deMello, Andrew J.

    2009-01-01

    We introduce microfluidics technologies as a key foundational technology for synthetic biology experimentation. Recent advances in the field of microfluidics are reviewed and the potential of such a technological platform to support the rapid development of synthetic biology solutions is discussed.

  13. Highly sensitive optical chemosensor for the detection of Cu using a ...

    Indian Academy of Sciences (India)

    Administrator

    Highly sensitive colorimetric chemosensor molecule RHN for selective detection of Cu. 2+ in ... colour development against the colourless blank during the sensing event, a feature that would facilitate ... ever reported, much attention has been.

  14. A highly sensitive, low-cost, wearable pressure sensor based on conductive hydrogel spheres

    KAUST Repository

    Tai, Yanlong; Mulle, Matthieu; Ventura, Isaac Aguilar; Lubineau, Gilles

    2015-01-01

    Wearable pressure sensing solutions have promising future for practical applications in health monitoring and human/machine interfaces. Here, a highly sensitive, low-cost, wearable pressure sensor based on conductive single-walled carbon nanotube

  15. High Sensitivity TSS Prediction: Estimates of Locations Where TSS Cannot Occur

    KAUST Repository

    Schaefer, Ulf; Kodzius, Rimantas; Kai, Chikatoshi; Kawai, Jun; Carninci, Piero; Hayashizaki, Yoshihide; Bajic, Vladimir B.

    2013-01-01

    from mouse and human genomes, we developed a methodology that allows us, by performing computational TSS prediction with very high sensitivity, to annotate, with a high accuracy in a strand specific manner, locations of mammalian genomes that are highly

  16. High Sensitivity Indium Phosphide Based Avalanche Photodiode Focal Plane Arrays, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — nLight has demonstrated highly-uniform APD arrays based on the highly sensitive InGaAs/InP material system. These results provide great promise for achieving the...

  17. Design, Performance and Calibration of the CMS Forward Calorimeter Wedges

    CERN Document Server

    Baiatian, G; Emeliantchik, Igor; Massolov, V; Shumeiko, Nikolai; Stefanovich, R; Damgov, Jordan; Dimitrov, Lubomir; Genchev, Vladimir; Piperov, Stefan; Vankov, Ivan; Litov, Leander; Bencze, Gyorgy; Laszlo, Andras; Pal, Andras; Vesztergombi, Gyorgy; Zálán, Peter; Fenyvesi, Andras; Bawa, Harinder Singh; Beri, Suman Bala; Bhatnager, V; Kaur, Manjit; Kumar, Arun; Kohli, Jatinder Mohan; Singh, Jas Bir; Acharya, Bannaje Sripathi; Chendvankar, Sanjay; Dugad, Shashikant; Kalmani, Suresh Devendrappa; Katta, S; Mazumdar, Kajari; Mondal, Naba Kumar; Nagaraj, P; Patil, Mandakini Ravindra; Reddy, L V; Satyanarayana, B; Sharma, Seema; Verma, Piyush; Hashemi, Majid; Mohammadi-Najafabadi, M; Paktinat, S; Babich, Kanstantsin; Golutvin, Igor; Kalagin, Vladimir; Kosarev, Ivan; Ladygin, Vladimir; Meshcheryakov, Gleb; Moissenz, P; Petrosian, A; Rogalev, Evgueni; Sergeyev, S; Smirnov, Vitaly; Vishnevski, A V; Volodko, Anton; Zarubin, Anatoli; Gavrilov, Vladimir; Gershtein, Yuri; Ilyina, N P; Kaftanov, Vitali; Kisselevich, I; Kolossov, V; Krokhotin, Andrey; Kuleshov, Sergey; Litvintsev, Dmitri; Oulyanov, A; Safronov, S; Semenov, Sergey; Stolin, Viatcheslav; Gribushin, Andrey; Demianov, A; Kodolova, Olga; Petrushanko, Sergey; Sarycheva, Ludmila; Teplov, Konstantin; Vardanyan, Irina; Yershov, A A; Abramov, Victor; Goncharov, Petr; Kalinin, Alexey; Korablev, Andrey; Khmelnikov, V A; Korneev, Yury; Krinitsyn, Alexander; Kryshkin, V; Lukanin, Vladimir; Pikalov, Vladimir; Ryazanov, Anton; Talov, Vladimir; Turchanovich, L K; Volkov, Alexey; Camporesi, Tiziano; De Visser, Theo; Vlassov, E; Aydin, Sezgin; Bakirci, Mustafa Numan; Cerci, Salim; Dumanoglu, Isa; Eskut, Eda; Kayis-Topaksu, A; Koylu, S; Kurt, Pelin; Kuzucu, A; Onengüt, G; Ozdes-Koca, N; Ozkurt, Halil; Sogut, Kenan; Topakli, Huseyin; Vergili, Mehmet; Yetkin, Taylan; Cankocak, Kerem; Gamsizkan, Halil; Ozkan, Cigdem; Sekmen, Sezen; Serin-Zeyrek, M; Sever, Ramazan; Yazgan, Efe; Zeyrek, Mehmet; Deliomeroglu, Mehmet; Dindar, Kamile; Gülmez, Erhan; Isiksal, Engin; Kaya, Mithat; Ozkorucuklu, Suat; Levchuk, Leonid; Sorokin, Pavel; Grinev, B; Lubinsky, V; Senchyshyn, Vitaliy; Anderson, E Walter; Hauptman, John M; Elias, John E; Freeman, Jim; Green, Dan; Heering, Arjan Hendrix; Lazic, Dragoslav; Los, Serguei; Ronzhin, Anatoly; Suzuki, Ichiro; Vidal, Richard; Whitmore, Juliana; Antchev, Georgy; Arcidy, M; Hazen, Eric; Lawlor, C; Machado, Emanuel; Posch, C; Rohlf, James; Sulak, Lawrence; Varela, F; Wu, Shouxiang; Adams, Mark Raymond; Burchesky, Kyle; Qiang, W; Abdullin, Salavat; Baden, Drew; Bard, Robert; Eno, Sarah Catherine; Grassi, Tullio; Jarvis, Chad; Kellogg, Richard G; Kunori, Shuichi; Mans, Jeremy; Skuja, Andris; Wang, Lei; Wetstein, Matthew; Ayan, S; Akgun, Ugur; Duru, Firdevs; Merlo, Jean-Pierre; Mestvirishvili, Alexi; Miller, Michael; Norbeck, Edwin; Olson, Jonathan; Onel, Yasar; Schmidt, Ianos; Akchurin, Nural; Carrell, Kenneth Wayne; Gumus, Kazim; Kim, Heejong; Spezziga, Mario; Thomas, Ray; Wigmans, Richard; Baarmand, Marc M; Mermerkaya, Hamit; Vodopyanov, I; Kramer, Laird; Linn, Stephan; Markowitz, Pete; Martínez, German; Cushman, Priscilla; Ma, Yousi; Sherwood, Brian; Cremaldi, Lucien Marcus; Reidy, Jim; Sanders, David A; Fisher, Wade Cameron; Tully, Christopher; Hagopian, Sharon; Hagopian, Vasken; Johnson, Kurtis F; Barnes, Virgil E; Laasanen, Alvin T; Pompos, Arnold

    2008-01-01

    We report on the test beam results and calibration methods using charged particles of the CMS Forward Calorimeter (HF). The HF calorimeter covers a large pseudorapidity region (3\\l |\\eta| \\le 5), and is essential for large number of physics channels with missing transverse energy. It is also expected to play a prominent role in the measurement of forward tagging jets in weak boson fusion channels. The HF calorimeter is based on steel absorber with embedded fused-silica-core optical fibers where Cherenkov radiation forms the basis of signal generation. Thus, the detector is essentially sensitive only to the electromagnetic shower core and is highly non-compensating (e/h \\approx 5). This feature is also manifest in narrow and relatively short showers compared to similar calorimeters based on ionization. The choice of fused-silica optical fibers as active material is dictated by its exceptional radiation hardness. The electromagnetic energy resolution is dominated by photoelectron statistics and can be expressed...

  18. High luminosity liquid-argon calorimeter test beam

    Energy Technology Data Exchange (ETDEWEB)

    Novgorodova, Olga; Straessner, Arno [TU Dresden, IKTP (Germany)

    2016-07-01

    In the future HL-LHC the luminosity will increase by factor of 5-7 with respect to the original LHC design. The HiLum collaboration studied the impact on small-sized modules of the ATLAS electromagnetic, hadronic, and forward calorimeters also instrumented by various intensity and position detectors. The intensity of beam varied over a wide range (10{sup 6} to 10{sup 12} p/s) and beyond the maximum expected at HL-LHC for these calorimeters. Results from the last test beam campaign in 2013 on the signal shape analysis from the calorimeter modules are compared with MC simulations. The correlation between high-voltage return currents of the electromagnetic calorimeter and beam intensity is used to estimate critical parameters and compared with predictions.

  19. Scintillation chamber of calorimeters for colliding beam detectors

    International Nuclear Information System (INIS)

    Jones, L.W.

    1983-01-01

    It is suggested that the scintillation chamber, a technique first discussed almost thirty years ago, might find application in colliding beam detector systems, in particular as a means of efficiently extracting detailed spatial and energy information from a sampling calorimeter

  20. Calibration of the CMS hadron calorimeter in Run 2

    Science.gov (United States)

    Chadeeva, M.; Lychkovskaya, N.

    2018-03-01

    Various calibration techniques for the CMS Hadron calorimeter in Run 2 and the results of calibration using 2016 collision data are presented. The radiation damage corrections, intercalibration of different channels using the phi-symmetry technique for barrel, endcap and forward calorimeter regions are described, as well as the intercalibration with muons of the outer hadron calorimeter. The achieved intercalibration precision is within 3%. The in situ energy scale calibration is performed in the barrel and endcap regions using isolated charged hadrons and in the forward calorimeter using the Zarrow ee process. The impact of pileup and the developed technique of correction for pileup is also discussed. The achieved uncertainty of the response to hadrons is 3.4% in the barrel and 2.6% in the endcap region (at the pseudorapidity range |η|<2) and is dominated by the systematic uncertainty due to pileup contributions.