WorldWideScience

Sample records for high-risk seronegative homosexual

  1. Prevalence of HIV infection in seronegative high-risk individuals examined by virus isolation and PCR

    DEFF Research Database (Denmark)

    Nielsen, C; Teglbjærg, Lars Stubbe; Pedersen, C

    1991-01-01

    HIV seronegative individuals with high-risk behavior were tested for HIV infection by sensitive virus isolation techniques using T4 lymphocytes and monocyte/macrophages, and by detection of proviral DNA using PCR with three different sets of nested primers. No evidence of HIV infection was found...... among the 31 seronegative high-risk subjects, either by virus isolation of by PCR (97.5% confidence limits, 0-11). Our results indicate that ongoing HIV infection in seronegative persons at high risk of infection is a rare event....

  2. Homosexuality

    OpenAIRE

    Barnecka, Joanna; Karp, Kinga; Lollike, Mie

    2005-01-01

    In the following project we are investigating different theories about origin of homosexuality, and we relate to them in the discussion about the theoretical background of reparative therapy of homosexuality. We present biological, behaviouristic and psychodynamic theoretical origins of the homosexual orientation, which is put into perspective by using Queer Theory – the new approach offering alternative to defining oneself on ones sexuality, which then becomes ones identity. The therapy ment...

  3. Analysis of serum immune markers in seropositive and seronegative rheumatoid arthritis and in high-risk seropositive arthralgia patients

    NARCIS (Netherlands)

    Chalan, Paulina; Bijzet, Johan; van den Berg, Anke; Kluiver, Joost; Kroesen, Bart-Jan; Boots, Annemieke M. H.; Brouwer, Elisabeth

    2016-01-01

    Presence of autoantibodies precedes development of seropositive rheumatoid arthritis (SP RA) and seropositive arthralgia patients (SAP) are at risk of developing RA. The aims of the study are to identify additional serum immune markers discriminating between SP and seronegative (SN) RA, and markers

  4. Markers of human immunodeficiency virus infection in high-risk individuals seronegative by first generation enzyme-linked immunosorbent assay

    DEFF Research Database (Denmark)

    Pedersen, C; Lindhardt, B O; Lauritzen, E

    1989-01-01

    -linked immunoassay (ELISA). Seventy-four of the serum samples had been obtained from 40 sexual partners of HIV antibody positive individuals. Two of the samples were reactive for p24 in immunoblot, but no other markers of HIV infection were found. From 80 sexually active male homosexuals, 117 serum samples were...

  5. Evolution of human cytomegalovirus-seronegative donor/-seropositive recipient high-risk combination frequency in allogeneic hematopoietic stem cell transplantations at Institute of Hematology and Blood Transfusion during 1995-2014.

    Science.gov (United States)

    Nemeckova, S; Sroller, V; Stastna-Markova, M

    2016-04-01

    Human cytomegalovirus (HCMV) establishes lifelong latent infection that can result in severe life-threatening disease in immunosuppressed patients after hematopoietic stem cell transplantation (HSCT). An HCMV-seropositive transplant recipient who receives a graft from a seronegative donor (R+/D-) is at high risk of recurrent HCMV reactivation. To assess the incidence of R+/D- combination, we retrospectively evaluated HCMV-seronegative donors for 746 allogeneic HSCT treatments carried out at our center during 1995-2014. In our cohort, 20% HCMV-seronegative HSCT recipients, 21% HCMV-seronegative related graft donors, and 52% HCMV-seronegative unrelated graft donors were included. Analyses of the HCMV serostatus of hematopoietic stem cell donors during 2 consecutive calendar periods (1995-2005 and 2006-2014) showed a significant increase in the proportion of seronegative donors (odds ratio [OR] = 1.947). In addition, the number of HSCT treatments using an unrelated donor increased (OR = 2.376). Finally, the use of grafts from countries with a very low HCMV prevalence increased. This increase in HCMV seronegativity in unrelated donors and the increased proportion of unrelated donors were responsible for the increased occurrence of the high-risk combination R+/D- (OR = 1.680). If the reduction in the rate of HCMV-seropositive graft donors continues, an increased frequency of HCMV reactivation events in our transplant recipients can be expected, because of the increasing occurrence of the high-risk R+/D- combination. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  6. Condom use and high-risk sexual acts in adult films: a comparison of heterosexual and homosexual films.

    Science.gov (United States)

    Grudzen, Corita R; Elliott, Marc N; Kerndt, Peter R; Schuster, Mark A; Brook, Robert H; Gelberg, Lillian

    2009-04-01

    We compared the prevalence of condom use during a variety of sexual acts portrayed in adult films produced for heterosexual and homosexual audiences to assess compliance with state Occupational Health and Safety Administration regulations. We analyzed 50 heterosexual and 50 male homosexual films released between August 1, 2005, and July 31, 2006, randomly selected from the distributor of 85% of the heterosexual adult films released each year in the United States. Penile-vaginal intercourse was protected with condoms in 3% of heterosexual scenes. Penile-anal intercourse, common in both heterosexual (42%) and homosexual (80%) scenes, was much less likely to be protected with condoms in heterosexual than in homosexual scenes (10% vs 78%; P film industry, especially the heterosexual industry, is not adhering to state occupational safety regulations.

  7. Condom Use and High-Risk Sexual Acts in Adult Films: A Comparison of Heterosexual and Homosexual Films

    Science.gov (United States)

    Elliott, Marc N.; Kerndt, Peter R.; Schuster, Mark A.; Brook, Robert H.; Gelberg, Lillian

    2009-01-01

    Objectives. We compared the prevalence of condom use during a variety of sexual acts portrayed in adult films produced for heterosexual and homosexual audiences to assess compliance with state Occupational Health and Safety Administration regulations. Methods. We analyzed 50 heterosexual and 50 male homosexual films released between August 1, 2005, and July 31, 2006, randomly selected from the distributor of 85% of the heterosexual adult films released each year in the United States. Results. Penile–vaginal intercourse was protected with condoms in 3% of heterosexual scenes. Penile–anal intercourse, common in both heterosexual (42%) and homosexual (80%) scenes, was much less likely to be protected with condoms in heterosexual than in homosexual scenes (10% vs 78%; P films. Conclusions. Heterosexual films were much less likely than were homosexual films to portray condom use, raising concerns about transmission of HIV and other sexually transmitted diseases, especially among performers in heterosexual adult films. In addition, the adult film industry, especially the heterosexual industry, is not adhering to state occupational safety regulations. PMID:19218178

  8. Hormonal levels among HIV-1-seropositive women compared with high-risk HIV-seronegative women during the menstrual cycle. Women's Health Study (WHS) 001 and WHS 001a Study Team.

    Science.gov (United States)

    Cu-Uvin, S; Wright, D J; Anderson, D; Kovacs, A; Watts, D H; Cohn, J; Landay, A; Reichelderfer, P S

    2000-10-01

    There is a paucity of normative data on hormonal levels among HIV-infected women. Hormonal levels may influence fertility and HIV-related immunological and virological factors. The objective of this study was to determine progesterone and estradiol levels during the menstrual cycle in HIV-seropositive women compared with high-risk seronegative women. The study enrolled 55 HIV-infected and 10 high-risk uninfected women with self-reported regular menstrual cycles (25-30-day cycles). Progesterone and estradiol levels were determined on a weekly basis for 8 weeks. The analysis included evaluations from the first complete menstrual cycle for the 54 HIV-infected and 9 uninfected women who had at least one complete cycle. The median age was 35 years for HIV-infected women and 36 years for uninfected women. The median CD4+ count for HIV-seropositive women was 210 cells/mm3. The median menstrual cycle length was 28 days (range 22-49 days) for HIV-infected women and 25 days (range 24-44 days) for uninfected women. The maximum progesterone level during the luteal phase was normal (>3.0 ng/ml) for 52 (96%) of 54 HIV-seropositive women and 7 (78%) of 9 HIV-seronegative women (p = 0.09, Fisher's exact test). The median maximum progesterone level was 12.2 ng/ml in HIV-seropositive women and 7.2 ng/ml in HIV-seronegative women (p = 0.07, Wilcoxon test). The median maximum estradiol value during the follicular phase was 148 pg/ml for HIV-seropositive women and 111 pg/ml for HIV-seronegative women (p = 0.04, Wilcoxon test). Among HIV-infected women, there were no significant differences in progesterone and estradiol levels by antiretroviral therapy, baseline plasma viral load, or median CD4+ cell count. We conclude that HIV-infected women with self-reported normal menstrual cycles have normal levels of progesterone and estradiol during the menstrual cycle.

  9. A study on male homosexual behavior

    OpenAIRE

    Ramachandran, R.; Viswanath, Sudha; Elangovan, P.; Saravanan, N.

    2015-01-01

    Introduction: Male homosexual behavior carries a high risk of transmitting sexually transmitted infections (STIs). Ignorance regarding the associated high risk, indulgence inspite of no natural homosexual orientation and not using protective barrier methods can affect the sexual health of adolescents and adults. Aim: (1) To assess the proportion of men who have sex with men (MSM) having a natural homosexual orientation compared to those who had acquired the homosexual behavior initially under...

  10. Immune defence against HIV-1 infection in HIV-1-exposed seronegative persons.

    Science.gov (United States)

    Schmechel, S C; Russell, N; Hladik, F; Lang, J; Wilson, A; Ha, R; Desbien, A; McElrath, M J

    2001-11-01

    Rare individuals who are repeatedly exposed to HIV-1 through unprotected sexual contact fail to acquire HIV-1 infection. These persons represent a unique study population to evaluate mechanisms by which HIV-1 replication is either prevented or controlled. We followed longitudinally a group of healthy HIV-1 seronegative persons each reporting repeated high-risk sexual activities with their HIV-1-infected partner at enrollment. The volunteers were primarily (90%) male homosexuals, maintaining high risk activities with their known infected partner (45%) or multiple other partners (61%). We evaluated the quantity and specificity of HIV-1-specific T cells in 31 exposed seronegatives (ES) using a IFN-gamma ELISPOT assay to enumerate T cells recognizing epitopes within HIV-1 Env, Gag, Pol and Nef. PBMC from only three of the 31 volunteers demonstrated ex vivo HIV-1-specific IFN-gamma secretion, in contrast to nearly 30% exhibiting cytolytic responses in previous studies. These findings suggest that if T cell responses in ES are induced by HIV-1 exposure, the frequency is at low levels in most of them, and below the level of detection using the ELISPOT assay. Alternative approaches to improve the sensitivity of detection may include use of dendritic cells as antigen-presenting cells in the ex vivo assay and more careful definition of the risk behavior and extent of HIV-1 exposure in conjunction with the evaluation of T cell responses.

  11. A study on male homosexual behavior.

    Science.gov (United States)

    Ramachandran, R; Viswanath, Sudha; Elangovan, P; Saravanan, N

    2015-01-01

    Male homosexual behavior carries a high risk of transmitting sexually transmitted infections (STIs). Ignorance regarding the associated high risk, indulgence inspite of no natural homosexual orientation and not using protective barrier methods can affect the sexual health of adolescents and adults. (1) To assess the proportion of men who have sex with men (MSM) having a natural homosexual orientation compared to those who had acquired the homosexual behavior initially under various circumstances (such as due to certain misconceptions, fear of having heterosexual contact, peer pressure, and influence of alcohol). (2) To assess the level of awareness regarding increased risk of transmission of STIs associated with homosexual behavior and regarding protective barrier methods. After obtaining consent from the subjects, questionnaire - based interview used for obtaining data for this observational (cross-sectional) study. (1) Of the 50 subjects, only about 25% had interest in homosexual behavior prior to initial episode. (2) About 50% subjects indulged in homosexual behavior due to lack/fear of having heterosexual contact. (3) About 60% subjects believed that homosexual behavior carried relatively lower risk of acquiring STIs and 68% subjects have had unprotected contact. (4) About 70% subjects had only acquired this behavior and nearly 60% subjects were interested in heterosexual marriage and not interested in further homosexual behavior. (1) Homosexuality is a natural orientation in some and an acquired behavior in the rest. (2) If homosexual behavior is acquired, due to misconceptions, then imparting sex education and awareness regarding involved risks, and the importance of protective barrier methods will prevent ignorance driven behavior. For those with natural homosexual orientation, the importance of protective barrier methods in homosexual behavior needs emphasis.

  12. Adolescent homosexuality.

    Science.gov (United States)

    Stronski Huwiler, S M; Remafedi, G

    1998-01-01

    Homosexuality has existed in all civilizations, but societal disapproval and cultural taboos have negatively influenced its recognition. A significant percentage of youths identify themselves as homosexual, and even more experience sex with the same sex or are confused about sexual feelings. A unifying etiological theory attributes the expression of sexual orientation to genes that shape the central nervous system's development, organization, and structure via prenatal sex steroids. Environmental factors may influence the expression of genetic potential. Several models of psychosocial development describe initial stages of awareness and confusion about same-sex attractions, followed by acknowledgement of homosexuality, disclosure to others, and eventual integration of sexual identity into a comprehensive sense of self. Stressors related to isolation, stigma, and violence may predispose homosexual adolescents to impaired social, emotional, and physical health, resulting in depression and suicide, school problems, substance abuse, running away eating disorders, risky sexual behavior, and illegal conduct. As with all adolescents, the overall goals in the care of homosexual youth are to promote normal adolescent development, social and emotional well-being, and physical health. A comprehensive, multidisciplinary approach is required to address medical, mental health, and psychosocial issues within the context of the adolescents' community and culture.

  13. Influenza-like syndrome in homosexual men: a prospective diagnostic study

    NARCIS (Netherlands)

    de Wolf, F.; Lange, J. M.; Bakker, M.; Tjong-A-Hung, S.; Hooykaas, C.; Coutinho, R.; van der Noordaa, J.; Goudsmit, J.

    1988-01-01

    In the course of a prospective study of the prevalence and incidence of infection with the human immunodeficiency virus (HIV) and risk factors for the acquired immune deficiency syndrome among 961 homosexual men, 97 initially HIV antibody seronegative men reported a febrile period lasting at least

  14. Evidence for homosexuality gene

    Energy Technology Data Exchange (ETDEWEB)

    Pool, R.

    1993-07-16

    A genetic analysis of 40 pairs of homosexual brothers has uncovered a region on the X chromosome that appears to contain a gene or genes for homosexuality. When analyzing the pedigrees of homosexual males, the researcheres found evidence that the trait has a higher likelihood of being passed through maternal genes. This led them to search the X chromosome for genes predisposing to homosexuality. The researchers examined the X chromosomes of pairs of homosexual brothers for regions of DNA that most or all had in common. Of the 40 sets of brothers, 33 shared a set of five markers in the q28 region of the long arm of the X chromosome. The linkage has a LOD score of 4.0, which translates into a 99.5% certainty that there is a gene or genes in this area that predispose males to homosexuality. The chief researcher warns, however, that this one site cannot explain all instances of homosexuality, since there were some cases where the trait seemed to be passed paternally. And even among those brothers where there was no evidence that the trait was passed paternally, seven sets of brothers did not share the Xq28 markers. It seems likely that homosexuality arises from a variety of causes.

  15. (AIDS) appeared among homosexuals

    African Journals Online (AJOL)

    FOBUR

    2006-10-17

    Oct 17, 2006 ... pregnancy is low but its occurrence in this study suggests the need to re-test the seronegative male partners after ... 9. Jos Journal of Medicine, Volume 10 No. 1 .... Substance abuse, alcohol consumption and cigarette.

  16. Does incest cause homosexuality?

    Science.gov (United States)

    Cameron, P; Cameron, K

    1995-04-01

    A random sample of 5,182 adults from 6 U.S. metropolitan areas were questioned about incestuous sexual relationships during childhood. Incest was disproportionately reported by both male and female bisexuals and homosexuals. 148 gays (7.7% of the sample) reported 14 (50%) of same-sex, and 7 (22%) of opposite-sex incestuous experiences, and 20 (69%) of same-sex and 2 (3%) of opposite-sex sexual experiences with other relatives. 88 lesbians (3% of the sample) reported 2 (33%) of same-sex incest and 7 (9%) of opposite-sex incest and 1 (17%) of same-sex and 10 (13%) of opposite-sex sexual experiences with other relatives. 12% of 98 male homosexuals vs 0.8% of 1,224 male heterosexuals with a brother reported brother-brother incest. These findings are consonant with those of other studies in which disproportionately more incest by homosexuals was reported. As opposed to an evolutionary genetic hypothesis, these data support the alternative that homosexuality may be learned, since homosexuals do not produce children at sustainable levels and the incidence of homosexuality varies as a function of various social factors. Incest cannot be excluded as a significant basis for homosexuality.

  17. Christian Intolerance of Homosexuality.

    Science.gov (United States)

    Greenberg, David F.; Bystryn, Marcia H.

    1982-01-01

    The broad acceptance of homosexuality in the ancient Mediterranean world ended in late antiquity with the spread of an asceticism hostile to all forms of sexual pleasure. Repression began as a consequence of organizational reforms in the church and class conflict associated with the commercialization of medieval society. (Author/AM)

  18. Homosexuality: Facts for Teens

    Science.gov (United States)

    ... Talking to Your Kids About VirginityTalking to Your Kids About Sex Home Family Health Kids and Teens Homosexuality: Facts ... by: familydoctor.org editorial staff Categories: Family Health, Kids and Teens, Prevention and Wellness, Sex and Birth Control, Sex and SexualityTags: female, Gay ...

  19. An assessment of high risk sexual behaviour and HIV transmission ...

    African Journals Online (AJOL)

    An assessment of high risk sexual behaviour and HIV transmission among migrant oil workers in the Niger Delta area of Nigeria. ... questionnaires to evaluate key high – risk sexual behavioral parameters such as multiplicity of sexual partners, bisexuality (closet homosexuality), high grade sexual behaviour and lesbianism.

  20. Etiology of homosexuality.

    Science.gov (United States)

    Headings, V E

    1980-08-01

    The range of expression of homosexuality and its association with certain cultural, environmental, and genetic factors are most consistent with the concept of a multifactorial trait. Additionally, genetic heterogeneity in this phenotype (alternative mutants corresponding to a single phenotype) is highly probable. In certain nonhuman and presumably in human species the normal sexual development of the hypothalamus is guided by an appropriate exposure to androgen at a critical early stage, and this in turn presumably contributes to sociopsychologic sex development. Particularly instructive in this regard have been the monogenic experiments of nature in man--XY females with insensitivity to androgens, congenital adrenal hyperplasia, and male pseudohermaphrodites (5-alpha-reductase deficiency). Additionally, in the human, sociopsychologic sex also appears to be molded by sex assigned at birth and sex of rearing. Several of the intersexuality syndromes and psychoses are accompanied by increased homosexuality, but a majority of homosexuals are not in these categories. A limited number of family studies, including twins, tentatively suggests a heritable risk, at least in some families.

  1. Out of DSM: Depathologizing Homosexuality

    OpenAIRE

    Drescher, Jack

    2015-01-01

    In 1973, the American Psychiatric Association (APA) removed the diagnosis of ?homosexuality? from the second edition of its Diagnostic and Statistical Manual (DSM). This resulted after comparing competing theories, those that pathologized homosexuality and those that viewed it as normal. In an effort to explain how that decision came about, this paper reviews some historical scientific theories and arguments that first led to the placement of homosexuality in DSM-I and DSM-II as well as alter...

  2. Seronegative Intestinal Villous Atrophy: A Diagnostic Challenge

    Directory of Open Access Journals (Sweden)

    Cláudio Martins

    2016-01-01

    Full Text Available Celiac disease is the most important cause of intestinal villous atrophy. Seronegative intestinal villous atrophy, including those that are nonresponsive to a gluten-free diet, is a diagnostic challenge. In these cases, before establishing the diagnosis of seronegative celiac disease, alternative etiologies of atrophic enteropathy should be considered. Recently, a new clinical entity responsible for seronegative villous atrophy was described—olmesartan-induced sprue-like enteropathy. Herein, we report two uncommon cases of atrophic enteropathy in patients with arterial hypertension under olmesartan, who presented with severe chronic diarrhea and significant involuntary weight loss. Further investigation revealed intestinal villous atrophy and intraepithelial lymphocytosis. Celiac disease and other causes of villous atrophy were ruled out. Drug-induced enteropathy was suspected and clinical improvement and histologic recovery were verified after olmesartan withdrawal. These cases highlight the importance for clinicians to maintain a high index of suspicion for olmesartan as a precipitant of sprue-like enteropathy.

  3. Decriminalising homosexuality in India.

    Science.gov (United States)

    Misra, Geetanjali

    2009-11-01

    This paper examines the successful fight against the provision in Section 377 of the Penal Code of India that criminalised private consensual sex between adults of the same sex. This law had led to serious discrimination against people engaging in homosexual acts, who were subjected to frequent beatings and blackmail attempts by police, who used the threat of prosecution against them. NGOs working with sexual minorities have also been harassed and sometimes charged under Section 377. By stigmatising homosexuality and threatening gay men with prison, the law is also likely to have impeded the battle against HIV. The provision was read down in July 2009 after an innovative, sustained, mass media campaign by activists. The Voices Against 377 coalition brought together sexuality and lesbian, gay, bisexual and transgender (LGBT) organisations, who were previously marginalised, with groups working in areas such as children's rights and feminist groups, showing that support for non-discrimination towards sexual minorities was broad-based. Further legal and social changes are needed for LGBT individuals to gain full acceptance and equality within Indian society. However, the judgement transcended the LGBT issue with the implication of protection for all minorities and introduced for the first time in South Asia the idea of sexual citizenship.

  4. Attitude Change among College Students toward Homosexuality.

    Science.gov (United States)

    Goldberg, Raymond

    1982-01-01

    College students' attitudes toward homosexuality changed after they participated in a program that taught about homosexuality through the use of: (1) a film on the topic of prejudice; (2) a videotape of a homosexual clergyman who discussed sexual variance; (3) two films in which couples engaged in homosexual behavior; and (4) a lecture. Results…

  5. Inappropriate lubricant use with condoms by homosexual men.

    OpenAIRE

    Martin, D J

    1992-01-01

    Use of condoms has been advocated as an important method of reducing the risk of human immunodeficiency virus (HIV) transmission among high-risk groups such as homosexual and bisexual men, prostitutes, intravenous drug users, adolescents, and hemophiliacs. Despite risk-reduction education campaigns directed to gay men since the early 1980s, evidence shows continued deficits in condom-use skills and knowledge among gay men. Because most failures in the use of condoms are attributed to errors i...

  6. Out of DSM: Depathologizing Homosexuality.

    Science.gov (United States)

    Drescher, Jack

    2015-12-04

    In 1973, the American Psychiatric Association (APA) removed the diagnosis of "homosexuality" from the second edition of its Diagnostic and Statistical Manual (DSM). This resulted after comparing competing theories, those that pathologized homosexuality and those that viewed it as normal. In an effort to explain how that decision came about, this paper reviews some historical scientific theories and arguments that first led to the placement of homosexuality in DSM-I and DSM-II as well as alternative theories that eventually led to its removal from DSM III and subsequent editions of the manual. The paper concludes with a discussion of the sociocultural aftermath of that 1973 decision.

  7. Psychobiology of Male Homosexuality: Recent Findings

    OpenAIRE

    Annicchiarico Iseda, Ivan Darío; Universidad Nacional de Colombia

    2009-01-01

    In this paper, empirical and theoretical reports which question the causes of male homosexuality are examined. According to these reports, male homosexuality differs from female homosexuality in some respects. Additionally, evidence favouring the consideration of male homosexuality as a biological condition is shown: there are brain differences between gay men and heterosexual men, there are genetic and perinatal factors associated to male homosexuality, there are cognitive and behavioral dif...

  8. Homosexuality: a dilemma in discourse!

    Science.gov (United States)

    Gulia, K K; Mallick, H N

    2010-01-01

    Homosexuality has been in practice even prior to its recorded history. In the Indian cultural context, discourse on sexuality had never gained an agreeable consensus from any platform. However, in the recent past, efforts were made by governmental and nongovernmental organizations to bring sex-related issues to the masses after speculation on presumably the fast spread of AIDS (acquired immuno-deficiency syndrome) particularly through illegal homosexual activities. Nevertheless, strong cultural and religious ideologies discouraged any valid discussions on homosexuality. In light of the given scenario, the present essay aimed to highlight several aspects of homosexuality that include a brief history, biological basis, effect of nature versus nurture, evolutionary perspective and related issues concerning general well-being and health.

  9. Seronegative neuromyelitis optica after cardiac transplantation.

    Science.gov (United States)

    Kim, Elecia; Van Vrancken, Michael; Shaji, Mohamed; Mir, Osman; Spak, Cedric W; Gupta, Manu; Shamim, Sadat A

    2016-01-01

    We report a case of a 42-year-old man who presented with progressive weakness and blindness over the course of several months and met criteria for seronegative neuromyelitis optica. This presentation was in the setting of immunosuppression following cardiac transplant. No infectious causes were found within the neuroaxis, and he ultimately died with complete blindness, quadriplegia, and respiratory failure attributed to panmyelitis and brain stem inflammation despite aggressive therapies.

  10. High-Risk List

    Science.gov (United States)

    2017-01-01

    economy. The World Bank has said that “corruption creates an unfavorable business environment by undermining the operation efficiency of firms and... Bank Began as ‘Ponzi Scheme,’” 11/27/2012. 64 Independent Joint Anti-Corruption Monitoring and Evaluation Committee, Unfinished Business : The Follow...HIGH RISK AREA 7: Oversight 51 HIGH-RISK AREA 8: Strategy and Planning 55 CONCLUSION HIGH RISK LIST I JANUARY 11, 2017 2 EXECUTIVE SUMMARY

  11. Some Observations About Homosexuality and Prejudice

    Science.gov (United States)

    Munter, Preston A.

    1973-01-01

    This article, noting some current change in attitude towards homosexuals, discusses the validity of certain beliefs about them and stresses the need for health care that is above prejudice for homosexuals and heterosexuals alike.

  12. Comments on radiology of the 'seronegative spondylarthritides'

    International Nuclear Information System (INIS)

    Schacherl, M.; Stollenwerk, R.

    1981-01-01

    Besides the common factors characterizing the diseases in the group of the seronegative spondylarthritides, a further radiological feature, namely, inflammatory enthesiopathy, is described. The article points to the problems connected with the radiological visualisation of the sacroiliac joints. An explanation of the radiological 'stepwise diagnosis' of the sacroiliac joints is given. The classification of the types of ankylosing spondylitis after Schilling is demonstrated. Comments are made on the chronic Reiter's syndrome (Reiter's disease), on spondylitis psoriatica, enteropathies, and on Behcet's syndrome. (orig./MG) [de

  13. Death in Venice : The homosexuality enigma

    NARCIS (Netherlands)

    Schuiling, GA

    A hypothesis is presented which regards homosexuality neither as an aberration of 'normal' human sexuality, i.e. heterosexuality, nor as a 'defect, genetically transmitted from parent(s) to offspring. Nor is homosexuality regarded as the regrettable result of accidental circumstances. Homosexuality,

  14. self concept and personality correlates amongst homosexuals

    African Journals Online (AJOL)

    2014-01-31

    Jan 31, 2014 ... liberation for homosexuality at its new height in. India, researchers are now trying to view homosexuals on empirically generated results rather than old stereotyped perceptions. In addition, Self concept and Personality are part of a homosexual's identity in the same way as it is for heterosexuals. Yet, the ...

  15. Sexual practices and condom usage in a cohort of homosexual men in relation to human immunodeficiency virus status.

    Science.gov (United States)

    Tindall, B; Swanson, C; Donovan, B; Cooper, D A

    1989-09-18

    Between January 1, and October 31, 1987, 420 homosexual men who participated in a cohort study of infection with the human immunodeficiency virus (HIV) completed a questionnaire that examined their sexual practices during the previous six months. Of the subjects, 205 (48.8%) men were HIV-seropositive and 215 (51.2%) men were HIV-seronegative. Although there was an appreciable level of condom usage in both groups, 13.5% of the HIV-seronegative men had engaged in unprotected receptive anal intercourse and 6.3% of the HIV-seropositive men had engaged in unprotected insertive anal intercourse. Condom breakage was reported on approximately 6% of occasions by a minority of subjects. Among subjects who were in a relationship with a regular male sexual partner, the most commonly reported sexual practices were deep kissing, mutual masturbation and receptive oral intercourse without ejaculation. No HIV-seronegative man engaged in unprotected receptive and/or insertive anal intercourse, receptive oral intercourse with ejaculation or receptive and/or insertive "fisting" with a regular partner who was HIV-seropositive. No HIV-seropositive man engaged in unprotected insertive anal intercourse to ejaculation with an HIV-seronegative partner, although they did so with partners who were HIV-seropositive or of unknown status. On multivariate analyses the subject's antibody status was found to be associated with receptive anal intercourse with a condom (P = 0.007) and mutual masturbation (P = 0.001), with HIV-seronegative men being more likely to practise either; no significant independent effect was associated with the partner's antibody status. These findings provide important information on the types and levels of sexual practices in a group of homosexual men after the recognition of the acquired immunodeficiency syndrome in this country.

  16. Reconsiderations about Greek homosexualities.

    Science.gov (United States)

    Percy, William Armstrong

    2005-01-01

    Focusing his analysis on (mostly Athenian) vase paintings of the sixth- and early fifth-century and on a handful of texts from the late fifth- and early fourth-century (again Athenian), Dover depicted the pederastic relationship of erastes (age 20 to 30) and eromenos (age 12-18) as defined by sexual roles, active and passive, respectively. This dichotomy he connected to other sexual and social phenomena, in which the active/ penetrating role was considered proper for a male adult Athenian citizen, while the passive/penetrated role was denigrated, ridiculed, and even punished. Constructing various social and psychological theories, Foucault and Halperin, along with a host of others, have extended his analysis, but at the core has remained the Dover dogma of sexual-role dichotomization. Penetration has become such a focal point in the scholarship that anything unable to be analyzed in terms of domination is downplayed or ignored. To reduce homosexuality or same-sex behaviors to the purely physical or sexual does an injustice to the complex phenomena of the Greek male experience. From Sparta to Athens to Thebes and beyond, the Greek world incorporated pederasty into their educational systems. Pederasty became a way to lead a boy into manhood and full participation in the polis, which meant not just participation in politics but primarily the ability to benefit the city in a wide range of potential ways. Thus the education, training, and even inspiration provided in the pederastic relationship released creative forces that led to what has been called the Greek 'miracle.' From around 630 BCE we find the institution of Greek pederasty informing the art and literature to a degree yet to be fully appreciated. Moreover, this influence not only extends to the 'higher' realms of culture, but also can be seen stimulating society at all levels, from the military to athletic games, from philosophy to historiography. An understanding of sexual practices-useful, even essential, to

  17. Seronegative myasthenia gravis associated with malignant thymoma.

    Science.gov (United States)

    Richards, Jason; Howard, James F

    2017-05-01

    Myasthenia gravis (MG) is generally caused by antibodies directed against the neuromuscular junction, including antibodies against the postsynaptic nicotinic acetylcholine receptor (AChR). Pathologic abnormalities of the thymus gland, including thymoma, are associated with MG. We report a 56-year-old woman who presented with double vision. Single fiber EMG confirmed myasthenia gravis. AChR, striational muscle and MuSK antibodies were absent in the serum. Chest CT demonstrated a malignant thymoma. We report the first case of seronegative myasthenia gravis associated with malignant thymoma. The case challenges the conventional wisdom that all patients with thymoma associated MG test positive for antibodies against AChR. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Out of DSM: Depathologizing Homosexuality

    Directory of Open Access Journals (Sweden)

    Jack Drescher

    2015-12-01

    Full Text Available In 1973, the American Psychiatric Association (APA removed the diagnosis of “homosexuality” from the second edition of its Diagnostic and Statistical Manual (DSM. This resulted after comparing competing theories, those that pathologized homosexuality and those that viewed it as normal. In an effort to explain how that decision came about, this paper reviews some historical scientific theories and arguments that first led to the placement of homosexuality in DSM-I and DSM-II as well as alternative theories that eventually led to its removal from DSM III and subsequent editions of the manual. The paper concludes with a discussion of the sociocultural aftermath of that 1973 decision.

  19. Pamidronate infusion improved two cases of intractable seronegative rheumatoid arthritise

    Directory of Open Access Journals (Sweden)

    Mansour Salesi

    2011-01-01

    Full Text Available Pamidronate is a bisphosphonate derivative that can inhibit bone resorption by actions on osteoclasts and increase bone density in spite of treatment with steroids. This drug has the anti-inflammatory effect by increase apoptosis of monocytes. 5-10 percent of rheumatoid arthritis patients is seronegative and may be resistant to conventional disease modifying anti rheumatic drugs (DMARDs. Intravenous (IV pamidronate can be effective in disease control in seronegative rheumatoid arthritis. We report two cases of seronegative and drug resistant rheumatoid arthritis that favorably responds to pamidronate.

  20. Male homosexuality: nature or culture?

    Science.gov (United States)

    Jannini, Emmanuele A; Blanchard, Ray; Camperio-Ciani, Andrea; Bancroft, John

    2010-10-01

    Debate continues on whether or not male homosexuality (MH) is a result of biological or cultural factors. The debate persists despite the fact that these two sides have different abilities to create a scientific environment to support their cause. Biological theorists produced evidence, however, that these are not always robust. On the other hand, social theorists, without direct evidence confirming their positions, criticize, with good argument, methods and results of the other side. The aim of this Controversy is to understand the reasons of both perspectives. Two scientists (R.B. and A.C.C.) with expertise in the area of biology of MH were asked to contribute their opinions. The nurture position is discussed by a third expert in sexology (J.B.). Expert opinion supported by the critical review of the currently available literature. The role of the Controversy's editor (E.A.J.) is to highlight the strengths and weaknesses of both sides. The two experts of the biological issue answer with their data to the questions: “Is male homosexuality partly explainable by immunology?” and “How is male homosexuality a Darwinian paradox?”, respectively. Genetic and immunological factors, birth order, and fertility of relatives are largely discussed. Finally, the expert sustaining the idea that culture and experiences are important determining factors in sexual orientation used a psychosocial and holistic perspective to explain his position. The JSM's readers should recognize that there are several biological factors in MH. However, these findings do not seem to be able to explain all cases of homosexuality. Some others may be due to particular environmental factors. The issue is complicated and multifactorial, suggesting that further research should be undertaken to produce the final answer to the question raised in this Controversy section.

  1. [Phalloplethysmographic findings in homosexual pedophile offenders].

    Science.gov (United States)

    Tichý, P

    1991-03-29

    Using phalloplethysmographic tests comprising 20 coloured slides of four categories the authors examined 50 homosexual pedophil delinquents and a matched group of heterosexual men. The findings of the two compared groups differed significantly on exposure to three categories of erotic stimuli--adult heterosexual and homosexual objects and child homosexual objects. Only on projection of child heterosexual objects there were no statistically significant differences in the number and magnitude of positive vasomotor reactions recorded in the two groups. Men in the control group responded more frequently and more positively to adult heterosexual objects than homosexual pedophil delinquents. The latter responded more frequently positively to adult and child homosexual objects. In more than one quarter of the delinquents (13 men) a preference of child objects was found, i.e. a deviant pedophil orientation. In seven men the preference of child objects was without sexual differentiation, six men preferred homosexual child objects.

  2. Psychological characteristics in high-risk MSM in China

    Directory of Open Access Journals (Sweden)

    Chen Guanzhi

    2012-01-01

    Full Text Available Abstract Background Men who have sex with men (MSM have become a high-risk group of HIV infection in China. To date, little is known regarding the behavioral, social and psychological characteristics in Chinese MSM, which makes the implementation of preventive and therapeutic strategies for this high-risk subpopulation of people extremely difficult. Methods A total of 714 questionnaires were retrieved from the database of a Chinese government-sponsored National Key Research Project titled "Risk Analysis and Strategic Prevention of HIV Transmission from MSM to the General Population in China". The respondents were categorized into a high-risk group and a control group. Their behavioral, social and psychological characteristics were comparatively analyzed. Results Of the 714 MSM analyzed, 59 (8.26% had high-risk homosexual behaviors. This sub-group of MSM had a higher in-marriage rate, a higher monthly income, heavier alcohol consumption and more serious problems with sexual abuse in childhood, intentional suicide attempts and mistaken assumption on condom's role in protecting HIV infection, as compared with the control group (P P > 0.05. A vast majority of the individuals in both behavior categories expressed support of legally protected gay clubs as well as gay marriage legislation in China. There was a strong correlation between high-risk behaviors and sexual abuse in childhood, alcohol drinking, income level and a mistaken belief in perfect HIV protection through the use of condoms. Conclusions MSM with and without high-risk homosexual behaviors have different social and psychological characteristics, which should be taken into account when implementing behavioral and therapeutic interventions aimed at preventing HIV/AIDS transmission among MSM as well as from MSM to the general population in China.

  3. Homosexuality-related stigma and sexual risk behaviors among men who have sex with men in Hanoi, Vietnam.

    Science.gov (United States)

    Ha, Huy; Risser, Jan M H; Ross, Michael W; Huynh, Nhung T; Nguyen, Huong T M

    2015-02-01

    This article examined the associations between three forms of homosexuality-related stigma (enacted, perceived, and internalized homosexual stigmas) with risky sexual behaviors, and to describe the mechanisms of these associations, among men who have sex with men (MSM) in Hanoi, Vietnam. We used respondent-driven sampling (RDS) to recruit 451 MSM into a cross-sectional study conducted from August 2010 to January 2011. Data were adjusted for recruitment patterns due to the RDS approach; logistic regression and path analyses were performed. Participants were young and single; most had attended at least some college. Nine out of ten participants engaged in sexual behaviors at moderate to high risk levels. Compared to those who had no enacted homosexual stigma, men having low and high levels of enacted homosexual stigma, respectively, were 2.23 times (95 % CI 1.35-3.69) and 2.20 times (95 % CI 1.04-4.76) more likely to engage in high levels of sexual risk behaviors. In addition, there was an indirect effect of perceived homosexual stigma and internalized homosexual stigma on sexual risk behaviors through depression and drug and alcohol use. Our study provides valuable information to our understanding of homosexual stigma in Vietnam, highlighting the need for provision of coping skills against stigma to the gay community and addressing drinking and drug use among MSM, to improve the current HIV prevention interventions in Vietnam.

  4. Military Policy toward Homosexuals: Scientific, Historic, and Legal Perspectives

    National Research Council Canada - National Science Library

    Davis, Jeffrey S

    1990-01-01

    This thesis examines military policy toward homosexuals. Scientific, historic, and legal perspectives are reviewed as they relate to current policy and the distinction between homosexual acts and homosexual status...

  5. [Detecting high risk pregnancy].

    Science.gov (United States)

    Doret, Muriel; Gaucherand, Pascal

    2009-12-20

    Antenatal care is aiming to reduce maternal land foetal mortality and morbidity. Maternal and foetal mortality can be due to different causes. Their knowledge allows identifying pregnancy (high risk pregnancy) with factors associated with an increased risk for maternal and/or foetal mortality and serious morbidity. Identification of high risk pregnancies and initiation of appropriate treatment and/or surveillance should improve maternal and/or foetal outcome. New risk factors are continuously described thanks to improvement in antenatal care and development in biology and cytopathology, increasing complexity in identifying high risk pregnancies. Level of risk can change all over the pregnancy. Ideally, it should be evaluated prior to the pregnancy and at each antenatal visit. Clinical examination is able to screen for intra-uterin growth restriction, pre-eclampsia, threatened for preterm labour; ultrasounds help in the diagnosis of foetal morphological anomalies, foetal chromosomal anomalies, placenta praevia and abnormal foetal growth; biological exams are used to screen for pre-eclampsia, gestational diabetes, trisomy 21 (for which screening method just changed), rhesus immunisation, seroconversion for toxoplasmosis or rubeola, unknown infectious disease (syphilis, hepatitis B, VIH). During pregnancy, most of the preventive strategies have to be initiated during the first trimester or even before conception. Prevention for neural-tube defects, neonatal hypocalcemia and listeriosis should be performed for all women. On the opposite, some measures are concerning only women with risk factors such as prevention for toxoplasmosis, rhesus immunization (which recently changed), tobacco complications and pre-eclampsia and intra-uterine growth factor restriction.

  6. Psychiatric Opinion and Homosexuality: A Short Report

    Science.gov (United States)

    Barr, R. F.; And Others

    1975-01-01

    In a survey of opinion among 100 psychiatrists and 93 trainees in Australia, the majority endorsed the view either that "homosexuality is a developmental anomaly not necessarily or commonly associated with neurotic symptoms" or that "homosexuality is a normal variant like left-handedness." (Author)

  7. Homosexuality in the Dutch Armed Forces 2006

    NARCIS (Netherlands)

    Anna Adolfsen; Saskia Keuzenkamp; m.m.v. Linda Mans

    2006-01-01

    Original title: Uniform uit de kast. This study looks at the attitudes of defence personnel to homosexuality. How do members of the military view homosexual colleagues? Can gays and lesbians working in the armed forces be open about their sexual preferences? Do they regard the armed forces as

  8. Adolescent Homosexuality and Concerns Regarding Disclosure.

    Science.gov (United States)

    Harrison, Therese W.

    2003-01-01

    With threats of being labeled abnormal or facing rejection, homosexual adolescents are pressured to hide their sexual identities. To provide optimal anticipatory guidance and support, professionals must understand the natural development of sexual attraction and the disclosure concerns and risks for developing homosexual adolescents (e.g., risk…

  9. A history of homosexuality and organized psychoanalysis.

    Science.gov (United States)

    Drescher, Jack

    2008-01-01

    Today the Academy of Psychoanalysis and Dynamic Psychiatry welcomes its gay and lesbian members. Yet at the time of its 1956 founding, organized psychoanalytic attitudes toward homosexuality could be reasonably characterized as hostile. First there was a transition from Freud's early views of homosexuality as immature to later neofreudian theories that pathologized same-sex attractions and behavior. Following the 1973 decision of the American Psychiatric Association to remove homosexuality from the DSM, homosexuality is now more commonly regarded as a normal variant of human sexuality. The history of psychoanalytic attitudes toward homosexuality reinforces the impression that psychoanalytic theories cannot be divorced from the political, cultural, and personal contexts in which they are formulated. This history also shows that analysts can take positions that either facilitate or obstruct tolerance and acceptance.

  10. [Clinical comments on female homosexuality].

    Science.gov (United States)

    Zeul, M

    1993-02-01

    In psychoanalytic theory, homosexual women are regarded as being possessed by violent hatred of the mother. They are held to identify with the male or the phallic and to display an absence of "normal" femaleness. Their attendant immaturity makes them incapable of love. The author takes issue with the assumption that normality is synonymous with mature, reciprocal heterosexuality. With reference to a case study of a homosexual woman, she traces the structure of a lesbian love relationship. The patient is the involuntary witness of sexual intercourse between the parents. The mixture of alarm and excitement which this arouses sparks off female desires that revive early libidinous experiences with the mother. The girl desires her mother, without however identifying with the father. In her later relationships with women she does not relate to her partners as a disguised man but as a woman. Identification with the father serves as a defence against the desire for-and the fear of-identification at a female level.

  11. Adolescent homosexuality and concerns regarding disclosure.

    Science.gov (United States)

    Harrison, Therese W

    2003-03-01

    Development of sexual identity in middle childhood and early adolescence is a natural process. However, it is more stressful for homosexual adolescents. Society continues to stigmatize and marginalize homosexuality. To avoid rejection and hostility, homosexual adolescents are pressured to hide their sexual identities. This fact compounds the anticipated normal developmental concerns of adolescence, and can create unique problems for the homosexual adolescents. Homosexuality can place them at risk for social stigmatization, isolation, depression, suicide, abuse, and rejection by their families and friends. During this exceptionally stressful time, both adolescent students and their families need anticipatory guidance and support. In providing anticipatory guidance, this article discusses critical roles played by professionals who work with adolescents in community or school settings. Included are insights into development of this normal variant of sexual attraction and orientation, risks that homosexual adolescent students may face as well as their disclosure concerns, and possible reactions families may have following disclosure. Supporting homosexual adolescents and their families is emphasized with regard to sensitively providing information, disclosure decisions, coping with stigmatization, and resiliency factors.

  12. Homosexual inmates in the Buchenwald Concentration Camp.

    Science.gov (United States)

    Röll, W

    1996-01-01

    The treatment of homosexual inmates in Nazi concentration camps is a subject which was largely ignored by historians in both West and East Germany after the war. Not until the 1980s, when research began to focus on some of the lesser-known victims of Nazi terror, did attention shift to the fate of homosexuals. This process can be seen clearly at the Buchenwald Memorial in the former GDR, the site of the persecution and also the death of considerable numbers of prisoners identified by the pink triangle on their clothing. The persecution of homosexuals in Nazi Germany began in 1933, even before Buchenwald was built in 1937. The Nazis aimed to eradicate homosexuality, which they saw as a threat to the survival of the German people. Incarceration in concentration camps like Buchenwald marked a stage in the radicalization of Nazi policy against homosexuals. There they were subjected to the harshest conditions and treated as the lowest of the low in the camp hierarchy. They were continually exposed to the terror of the SS but also the latent prejudices of the rest of the camp population. The culminating points of their maltreatment in Buchenwald were the use of homosexuals in experiments to develop immunization against typhus fever and the attempt by an SS doctor to "cure" homosexuality through the implantation of sexual hormones.

  13. Seronegative Bilateral Symmetrical Inflammatory Polyarthritis: Think Twice Before Starting Immunosuppression

    Directory of Open Access Journals (Sweden)

    Omar Alsaed

    2018-06-01

    Full Text Available The most common cause of bilateral symmetrical polyarthritis in the small joints is rheumatoid arthritis. However, if seronegative arthritis is involved, it could be the case that other underlying causes need to be diagnosed. This is particularly important for those coming from or living in developing countries where infectious causes should always be considered. The case of a young Nepali woman is presented in this article. She was referred as a case of seronegative rheumatoid arthritis for DMARDs therapy but this was not the case due to her origin from Nepal and seronegativity for RF, Anti-ccp, and ANA as well as faint macular skin lesions over her face and upper extremities, which the patients are not aware of. Consequently, skin biopsy was carried out which subsequently confirmed that the infectious cause of her polyarthritis was leprosy.

  14. Homosexuality and police terror in Turkey.

    Science.gov (United States)

    Yuzgun, A

    1993-01-01

    Being a way of sexual living as old as human history, homosexuality occupies an interesting place in the life of the Turkish people of the Republic of Turkey. This has been so since the days of the glorious Ottoman Empire. In the year 1987, instead of investigating the roots of homosexuality, the pressing need has become to present a particular view of homosexuality in Turkey today. To be more specific, there is a need to explain the problems of Turkish homosexuals and suggest certain vital solutions. Our country is constantly endeavoring to become "westernized" and it is claimed that steps are being taken toward that modernization. Despite this fact, homosexuals are confronted with such great problems that it is not difficult to justify those who say that there is no democracy in Turkey. I will try to explain these problems with documentary evidence and without exaggeration. In doing so, I shall make use of new material in my book, published under the title of Homosexuality in Turkey: Yesterday, Today. Beginning in March of 1986, we compiled a list of the attitudes of the police toward gays, involving pressure and cruelty that can be qualified as torture. Despite this situation, instead of being more democratic and humane, in April 1987 the police force employed terror tactics against homosexuals in Istanbul. This was "the straw that broke the camel's back." Soon after this act of oppression, 18 gays, acting on our suggestions, sued the police for the first time. They then submitted a petition to the Attorney-General and later launched a hunger strike in Taksim Square. These represent movements of importance in the political history of Turkey. From now on homosexuals, too, will have the right to speak out in political affairs.

  15. A neuroendocrine predisposition for homosexuality in men.

    Science.gov (United States)

    Dörner, G; Rohde, W; Stahl, F; Krell, L; Masius, W G

    1975-01-01

    In male rats, androgen deficiency during a critical hypothalamic organizational period was shown to give rise to a predominantly female-differentiated brain, homosexual behavior, and demonstration of a positive estrogen feedback effect. A positive estrogen feedback effect was also induced in intact homosexual men in contrast to intact heterosexual and bisexual men. Thus in 21 homosexual men an intravenous injection of 20 mg Presomen (Premarin) produced a significant decrease of serum LH levels followed by an increase above initial LH values. In 20 heterosexual and in five bisexual men, by contrast, intravenous estrogen administration, while producing a significant decrease of the serum LH level, was not followed by an increase above the initial LH values. Using a radioimmunoassay, plasma testosterone levels and 24-hr urinary excretions of unconjugated testosterone of adult homosexual men were found to be in the normal range as observed in heterosexual men. This finding suggests that homosexual men possess a predominantly female-differentiated brain which may be activated to homosexual behavior by normal or approximately normal androgen levels in adulthood.

  16. Death in Venice: the homosexuality enigma.

    Science.gov (United States)

    Schuiling, G A

    2004-03-01

    A hypothesis is presented which regards homosexuality neither as an aberration of 'normal' human sexuality, i.e. heterosexuality, nor as a 'defect', genetically transmitted from parent(s) to offspring. Nor is homosexuality regarded as the regrettable result of accidental circumstances. Homosexuality, it is maintained, is simply inherent in the human reproductive strategy; an option which evolved during the millions of years of human evolution as a solution for problems inherent in a polygynic, yet social species living in relatively small groups: homosexuality diminishes intra-male competition on the 'reproductive market'. This enables males to work closely together in all fields of society (hunting, war etc), rather than competing with each other for access to females. Homosexuality thus largely contributes to group stability. However, because our present-day situation differs vastly from the situation in which the human reproductive strategy evolved, the phenomenon hardly plays a role any more in the maintainance of the fitness and the stability of the population as a whole. Instead, due to 'cultural', often religious prejudices, homosexuals nowadays are treated as belonging to an 'out-group', and discriminated against accordingly.

  17. Sexually antagonistic selection in human male homosexuality.

    Directory of Open Access Journals (Sweden)

    Andrea Camperio Ciani

    Full Text Available Several lines of evidence indicate the existence of genetic factors influencing male homosexuality and bisexuality. In spite of its relatively low frequency, the stable permanence in all human populations of this apparently detrimental trait constitutes a puzzling 'Darwinian paradox'. Furthermore, several studies have pointed out relevant asymmetries in the distribution of both male homosexuality and of female fecundity in the parental lines of homosexual vs. heterosexual males. A number of hypotheses have attempted to give an evolutionary explanation for the long-standing persistence of this trait, and for its asymmetric distribution in family lines; however a satisfactory understanding of the population genetics of male homosexuality is lacking at present. We perform a systematic mathematical analysis of the propagation and equilibrium of the putative genetic factors for male homosexuality in the population, based on the selection equation for one or two diallelic loci and Bayesian statistics for pedigree investigation. We show that only the two-locus genetic model with at least one locus on the X chromosome, and in which gene expression is sexually antagonistic (increasing female fitness but decreasing male fitness, accounts for all known empirical data. Our results help clarify the basic evolutionary dynamics of male homosexuality, establishing this as a clearly ascertained sexually antagonistic human trait.

  18. Course and prognosis in seropositive and seronegative rheumatoid arthritis.

    Science.gov (United States)

    Sahatçiu-Meka, Vjollca; Rexhepi, Sylejman; Kukeli, Anton; Manxhuka-Kërliu, Suzana; Pallaskas, Kelmend; Murtezani, Ardiana; Rexhepi, Mjellma; Rexhepi, Blerta

    2013-01-01

    Long since it have been suggested that a subpopulation of patients with rheumatoid arthritis (RA), diagnosed with negative rheumatoid factor (RF) tests, represents a clinical entity quite distinct from that of seropositive rheumatoid arthritis. The aim of the study was to establish a scientific comparative analysis between RA seronegative and seropositive, regarding course and prognoses of the disease. Two hundred fifty patients with rheumatoid arthritis according to the (American College of Rheumatology) criteria were retrospectively studied by analysis the course and prognoses of disease. All examinees were between 25-60 years of age (Xb=49.9, SD=10.3) with disease duration between 1-27 years (Xbox=6.41, SD=6.47). Course of the disease with "remissions and exacerbations", progressive continual course and bad prognoses, were more presented in seropositive group ofpatients. Partial remission was more common in seronegative patients but according to serostatus and gender has not shown statistically significant difference. Duration of the disease was a specific prognostic sign for both subsets [(r=0.32, p0.05) seronegative, (r=0.18, p<0.05) seropositive]. Seropositive and seronegative RA distinguish in course and prognostic feature, but not enough to differentiate them in two different forms of the disease. Regarding the sero-status, differences within sex, with some exceptions, are not relevant.

  19. Association of Vogt Koyanagi Harada Syndrome and Seronegative ...

    African Journals Online (AJOL)

    Association of Vogt Koyanagi Harada Syndrome and Seronegative Rheumatoid Arthritis. Teoman Aydin, Ozgur Taspinar, Meryem Guneser, Yasar Keskin. Abstract. Background: Vogt Koyanagi Harada (VKH) Syndrome is a rarely-seen multi-systemic, autoimmune and inflammatory disease. It observed frequently with ...

  20. Seronegative Neuromyelitis Optica: A Case Report of a Hispanic Male

    Directory of Open Access Journals (Sweden)

    Nabeel Badri

    2016-05-01

    Full Text Available Neuromyelitis optica (NMO is a rare disease, common in white females and rarely reported in Hispanic males. It is usually associated with recurrent demyelinating spectrum that is autoimmune in nature. The diagnosis is usually confirmed by antibody biomarkers; however, they can be negative and lead to more dilemma in diagnosis. Furthermore, the course of disease and prognosis are different in seronegative as compared to seropositive NMO. Treatment is similar in both subgroups with new approaches under investigation for seronegative NMO patients. We present an interesting case of a 37-year-old Hispanic male who presented with sudden onset of lower extremity weakness, numbness, blurry vision, and urinary retention. Magnetic resonance imaging (MRI of the thoracic spine showed multiphasic demyelinating process involving the thoracic spinal cord. His brain MRI also revealed changes suggesting optic neuritis. The patient met the criteria for diagnosis of NMO by having optic neuritis and myelitis by imaging studies despite having negative aquaporin-4 antibodies (AQP4-Ab. His condition improved after plasma exchange. NMO can be difficult to distinguish from acute multiple sclerosis in the early stages of the disease. Having AQP4-Ab testing is important for diagnosis with imaging studies; however, negative antibody results cannot exclude the diagnosis, but rather group it in seronegative subtype. Ongoing studies and research suggest that seronegative NMO might have a different pathophysiology, manifestation, and prognosis.

  1. On the history of biological theories of homosexuality.

    Science.gov (United States)

    Herrn, R

    1995-01-01

    Biological theories of homosexuality fit into the discourse on reproduction and sexuality that began in the nineteenth century. They arose in the context of the early homosexual rights movement, with its claim for natural rights, and the psychiatric discussions about sexual perversions. With the classification of homosexuality as a distinct category, homosexuals were excluded from the "normal". Biological theories of homosexuality were attempts not only to explain its causes, but also to maintain the exclusion of homosexuals as the "other". Biological explanations can be categorized as genetic, constitutional, endocrinological, and ethological. On the one hand, biological theories were used in the struggle for homosexual rights. On the other hand, they were used to "cure"e homosexuals. Every theory led to a specific therapy. This paper points out the roots of this thinking, traces the development of various theories, and shows the utilization of biological theories in treating homosexuality.

  2. A further assessment of Blanchard's typology of homosexual versus non-homosexual or autogynephilic gender dysphoria.

    Science.gov (United States)

    Nuttbrock, Larry; Bockting, Walter; Mason, Mona; Hwahng, Sel; Rosenblum, Andrew; Macri, Monica; Becker, Jeffrey

    2011-04-01

    In a series of important but now highly controversial articles, Blanchard examined associations of sexual orientation and transvestic fetishism among male-to-female (MTF) transgender persons in Toronto, Canada. Transvestic fetishism was rare among the homosexuals but prevalent among the non-homosexuals. Subtypes of non-homosexual MTFs (heterosexual, bisexual, and asexual) were consistently high with regard to transvestic fetishism. Non-linear associations of a continuous measurement of sexual attraction to women (gynephilia) and transvestic fetishism were interpreted in terms of an etiological hypothesis in which transvestic fetishism interferes with the early development of heterosexuality. Blanchard concluded that homosexual versus non-homosexual sexual orientation is a dominant and etiologically significant axis for evaluating and understanding this population. We further assessed these findings among 571 MTFs from the New York City metropolitan area. Using the Life Chart Interview, multiple measurements of transvestic fetishism were obtained and classified as lifetime, lifecourse persistent, adolescent limited, and adult onset. Large (but not deterministic) differences in lifetime, lifecourse persistent, and adolescent limited transvestic fetishism were found between the homosexuals and non-homosexuals. Contrary to Blanchard, differences in transvestic fetishism were observed across subtypes of the non-homosexuals, and linear (not curvilinear) associations were found along a continuous measurement of gynephilia and transvestic fetishism. Age and ethnicity, in addition to sexual orientation, were found to be statistically significant predictors of transvestic fetishism. The clinical, etiological, and sociopolitical implications of these findings are discussed.

  3. From reassurance to irrelevance: adolescent psychology and homosexuality in America.

    Science.gov (United States)

    Spurlock, J C

    2002-02-01

    American psychology by the 1920s contained a greater capacity for viewing some homosexual experiences as normal than most current historical literature suggests. Developmental psychologists agreed with psychiatrists that adult homosexuality was pathological, but they also agreed that adolescent sexual development included a homosexual phase. Until the late 1960s, developmental texts reassured parents and teachers that homosexual behavior among adolescents was transitory and quite normal. The psychiatric view of homosexuality as pathology came under attack after the middle of the century and eventually was abandoned. The developmental concern with a transitory homosexual phase disappeared gradually. This trend in psychology suggests underlying social and cultural changes.

  4. Participants in urban Mexican male homosexual encounters.

    Science.gov (United States)

    Carrier, J M

    1971-12-01

    Preliminary data are presented on 53 urban Mexican males interviewed during 1970-1971 in a study of homosexual encounters in a large Mexican city. These data are compared with data from recent studies in the United States and England of male homosexual behavior. Although preliminary and limited, the Mexican data indicate that cultural factors are important determinants of life styles and sex practices of homosexual males. Forty-eight of the 53 (90%) preferred and usually practiced anal intercourse, four preferred oral contacts, and one preferred mutual masturbation. Interviewees were also grouped according to major type of sex activity during the first sustained year of homosexual activity after puberty. One intragroup comparison indicates significant differences between anal active and anal passive interviewees. For example, as children anal passive subjects had significantly more homosexual contacts with adults; they also considered themselves more effeminate and as children were more involved with female sex-typed activities. Comparison of data from the English and United States studies with the present data suggests that preference for a particular sexual technique is not as developed in the former two countries; when there is a preference, it is not usually for anal intercourse.

  5. PCR analysis is superior to histology for diagnosis of Whipple's disease mimicking seronegative rheumatic diseases.

    Science.gov (United States)

    Lehmann, P; Ehrenstein, B; Hartung, W; Dragonas, C; Reischl, U; Fleck, M

    2017-03-01

    The diagnosis of Whipple's disease (WD) is commonly confirmed by histology demonstrating Periodic Acid Schiff (PAS)-positive macrophages in the duodenal mucosa. Analysis of intestinal tissue or other specimens using polymerase chain reaction (PCR) is a more sensitive method. However, the relevance of positive PCR findings is still controversial. Therefore, we evaluated the relevance of histology and PCR findings to establishing the diagnosis of WD in a series of WD patients initially presenting with suspected rheumatic diseases. Between 2006 and 2014, 20 patients with seronegative rheumatic diseases tested positive for Tropheryma whipplei (Tw) by PCR and/or histology and were enrolled in a retrospective analysis of the diagnostic value of both procedures. Seven of the 20 cases (35%) were diagnosed with 'classic' WD as indicated by PAS-positive macrophages. In the remaining 13 patients, the presence of Tw was detected by intestinal (n = 10) or synovial PCR analysis (n = 3). Two of the 20 patients (10%) with evidence of Tw did not respond to antibiotic therapy. They were not considered to suffer from WD. Therefore, relying only on histological findings of intestinal biopsies would have missed 11 (61%) of the 18 patients with WD in our cohort. In comparison, PCR of intestinal biopsies detected Tw-DNA in 14 (93%) of the 15 WD patients evaluated. Patients with a positive histology did not differ from PCR-positive patients with regard to sex, age, or duration of disease, but more often presented with gastrointestinal symptoms. A substantial number of WD patients present without typical intestinal histology findings. Additional PCR analysis of intestinal tissue or synovial fluid increased the sensitivity of the diagnostic evaluation and should be considered particularly in patients presenting with atypical seronegative rheumatic diseases and a high-risk profile for WD.

  6. Dengvaxia sensitizes seronegatives to vaccine enhanced disease regardless of age.

    Science.gov (United States)

    Halstead, Scott B

    2017-11-07

    During a large scale clinical efficacy trial of the Sanofipasteur live-attenuated tetravalent dengue vaccine (Dengvaxia), features of hospitalized disease accompanying dengue infections in placebo recipients were closely similar to those in vaccinated children. However, the age specific hospitalization curves for these two populations differed. The curve for children vaccinated at ages 2-16 years closely resembled the 1981 age specific hospitalization rate curve for Cuban children infected with DENV 2 who were sensitized by a prior DENV 1 infection. The corresponding age specific hospitalization curve for placebos experiencing heterotypic secondary dengue infections peaked at age, 9-11 years. These differing epidemiological features support the conclusion that antibody dependent enhanced (ADE) dengue disease occurred in seronegatives who were sensitized by vaccine. As hospitalizations continue to occur in all age groups Dengvaxia consumers should be warned that sensitized vaccinated seronegatives will experience enhanced dengue disease into the forseeable future. Copyright © 2017 Elsevier Ltd. All rights reserved.

  7. Polypharmacy, Infectious Diseases, Sexual Behavior, and Psychophysical Health Among Anabolic Steroid-Using Homosexual and Heterosexual Gym Patrons in San Francisco's Castro District.

    Science.gov (United States)

    Ip, Eric J; Yadao, Michael A; Shah, Bijal M; Doroudgar, Shadi; Perry, Paul J; Tenerowicz, Michael J; Newsom, Lindsay; Mann, Amber A; Mkrtchyan, Hermine; Pope, Harrison G

    2017-06-07

    Limited studies based in England and Australia reported misuse of anabolic-androgenic steroids (AAS) among homosexual men to enhance body image. Anecdotally, AAS are also being misused by homosexual men in the United States. Since many AAS and certain performance enhancing drugs (PEDs) are administered via injection, this poses a potential vector for the spread of infectious disease in an already at-risk population. This study compared and contrasted homosexual and heterosexual male gym clients regarding use of AAS and PEDs, use of alcohol and illicit drugs, seroprevalence of infectious disease, engagement in risky injection practices and sexual behaviors, and presence of psychiatric conditions. Recruitment and data collection occurred outside four exercise gyms in the San Francisco Castro District area between October 25, 2014 and March 10, 2015. Two hundred and twenty homosexual men and 73 heterosexual men completed the 114-item cross-sectional survey. Ten percent of homosexual men reported lifetime AAS use. Homosexual men had almost four times more sexual partners and were over 14 times more likely to knowingly have unprotected intercourse with a known HIV positive person than heterosexual men. In addition, a quarter of homosexual men who injected drugs admitted to sharing used syringes or needles with another person. Conclusions/Importance: The current study is the first to confirm AAS use among homosexual men in the United States. Homosexual men partook in high-risk sexual behaviors and injection practices which may place them at greater risks for contracting and spreading HIV and other infectious diseases.

  8. Male homosexuality and spirit possession in Brazil.

    Science.gov (United States)

    Fry, P

    1985-01-01

    This paper examines the relationship between male homosexuality and the Afro-Brazilian possession cults in Belém do Parà. After a discussion of the literature follows a description of the cults' beliefs, rites and social organization. Male sex roles are then discussed and the two categories, bicha and man, analyzed. It is noted that there is no term which is equivalent to the western category of "homosexual" in this taxonomic system. After putting forward folk explanations for the presence of many bichas in the cults, an analysis is put forward of the social rewards available to bichas within these cults, and the structural relationship between homosexuality and these regions in terms of their congruent marginality vis-à-vis "normal society."

  9. Radiographic estimation in seropositive and seronegative rheumatoid arthritis.

    Science.gov (United States)

    Sahatçiu-Meka, Vjollca; Rexhepi, Sylejman; Manxhuka-Kërliu, Suzana; Rexhepi, Mjellma

    2011-08-01

    Long since it have been suggested that a subpopulation of patients with rheumatoid arthritis, diagnosed with negative rheumatoid factor tests, represents a clinical entity quite distinct from that of seropositive rheumatoid arthritis (RA). Our aim was to establish a scientific comparative analysis between seronegative and seropositive rheumatoid arthritis, regarding some radiological and clinical parameters, applied for the first time on patients from Kosovo. Two hundred fifty patients with rheumatoid arthritis according to the American College of Rheumatology criteria were retrospectively studied by analysis the radiographic damage and clinical parameters of the disease, using a data base. All examinees were between 25-60 years of age (Xb=49.96, SD=10.37) with disease duration between 1-27 years (Xb = 6.41, SD=6.47). All patients underwent a standardised evaluation radiographs. Baseline standardised poster anterior radiographs of hands and feet and radiographs of other joints, depending on indications, were assessed. Erythrocyte sedimentation rate values correlated with the radiological damages and statistical difference was found for seronegative subset (r=0.24, p<0.01). Longer duration of the disease resulted in the increase of radiological changes in both subsets (r=0.66, p<0.01) seronegative, (r=0.49, p<0.01) seropositive. Anatomic changes of IInd and IIIrd level were nearly equally distributed in both subsets, 76 (60.8%) seronegative, 75 (60%) seropositive. Radiological damages are nearly equal in both subsets, elevate in relation to the duration of the disease and correlate with ESR values. Regarding the sero-status, differences within sex, with some exceptions, are not relevant. Although there are some definite quantitative and qualitative differences regarding sero-status, obviously there is a great deal of overlap between the two groups.

  10. Radiographic estimation in seropositive and seronegative rheumatoid arthritis

    Directory of Open Access Journals (Sweden)

    Vjollca Sahatçiu-Meka

    2011-08-01

    Full Text Available Long since it have been suggested that a subpopulation of patients with rheumatoid arthritis, diagnosed with negative rheumatoid factor tests, represents a clinical entity quite distinct from that of seropositive rheumatoid arthritis (RA. Our aim was to establish a scientific comparative analysis between seronegative and seropositive rheumatoid arthritis, regarding some radiological and clinical parameters, applied for the first time on patients from Kosovo. Two hundred fifty patients with rheumatoid arthritis according to the American College of Rheumatology criteria were retrospectively studied by analysis the radiographic damage and clinical parameters of the disease, using a data base. All examinees were between 25-60 years of age (Xb=49.96, SD=10.37 with disease duration between 1-27 years (Xb = 6.41, SD=6.47. All patients underwent a standardised evaluation radiographs. Baseline standardised poster anterior radiographs of hands and feet and radiographs of other joints, depending on indications, were assessed. Erythrocyte sedimentation rate values correlated with the radiological damages and statistical difference was found for seronegative subset (r=0.24, p<0.01. Longer duration of the disease resulted in the increase of radiological changes in both subsets (r=0.66, p<0.01 seronegative, (r=0.49, p<0.01 seropositive. Anatomic changes of IInd and IIIrd level were nearly equally distributed in both subsets, 76 (60.8% seronegative, 75 (60% seropositive. Radiological damages are nearly equal in both subsets, elevate in relation to the duration of the disease and correlate with ESR values. Regarding the sero-status, differences within sex, with some exceptions, are not relevant. Although there are some definite quantitative and qualitative differences regarding sero-status, obviously there is a great deal of overlap between the two groups.

  11. Detection of sexual orientation ("gaydar") by homosexual and heterosexual women.

    Science.gov (United States)

    Lyons, Minna; Lynch, Aoife; Brewer, Gayle; Bruno, Davide

    2014-02-01

    Although there has been considerable research investigating the ability to identify sexual orientation from static images, or "gaydar," few studies have considered the role of female sexual orientation or sexual interest (for example, sociosexual orientation) in judgment accuracy. In two studies, we investigated the sexuality detection ability, and masculinity and femininity as cues used in judgment. In Study 1, we recruited heterosexual (N = 55) and homosexual (N = 71) women to rate the sexual orientation of homosexual and heterosexual male and female targets (N = 80: 20 heterosexual men, 20 homosexual men, 20 heterosexual women, and 20 homosexual women). We found that detection accuracy was better than chance levels for both male and female targets and that male targets were more likely to be falsely labeled as homosexual than female targets were. Overall, female faces were more accurately identified as heterosexual or homosexual than male faces and homosexual female raters were biased towards labeling targets as homosexual. Sociosexuality did not influence the accuracy with which targets were identified as heterosexual or homosexual. In Study 2, 100 heterosexual and 20 homosexual women rated the stimulus for masculinity and femininity. Heterosexual women were rated as more feminine and less masculine than homosexual women and homosexual men were rated as more feminine and less masculine than heterosexual men. Sexual orientation of the judges did not affect the ratings. The results were discussed with a reference to evolutionary and cultural influences affecting sexual orientation judgment accuracy.

  12. Homosexuality according to ancient Greek physicians.

    Science.gov (United States)

    Laios, K; Moschos, M M; Koukaki, E; Kontaxaki, M-I; Androutsos, G

    2017-01-01

    Homosexuality and pedophilia in ancient Greece greatly concerned many researchers who were mainly interested in highlighting the social aspect of this phenomenon in ancient Greek society. An important source on the subject was the paintings of a man and his lover in attic black and red figured pottery, up to the end of the 5th century BC. Another main source was the information that derived from the texts of ancient Greek literature, especially poetry. Homosexuality was not only referring to relationships between males, but it was also manifested in lesbian love. It is believed that in the Homeric world homosexuality was not favored. In Greek society of the archaic period, the restriction of women at home, the satisfaction of sexual needs with courtesans, the marriage for the purpose of maintaining and managing the property, put women aside, marginalizing them in terms of social life, impeding the cultivation of emotional relationships between sexes. At the same time, in the society of those times, the aristocratic ideal, the constant communication of men during military training and the war, the male nudity in sports and the promotion of beauty and bravery in athletic contests, as well as the gatherings and the entertainment of men at the symposia, created a suitable substrate in which male homosexuality could develop. In this context, pedophile relationships were developed mainly during the archaic period, as recorded on vase paintings, where a mature man developed a special relationship with a teenager of the same social class. The mature man had the role of mentor for the juvenile, he would look after him and cover his living expenses and education cost. In this relationship, exhibiting predominantly the social dimension of an initiation process and introduction to adult life, the erotic homosexual intercourse could find a place to flourish. The above-mentioned relationship could not last forever, given that this would later transform into an emotional

  13. When Christianity and homosexuality collide: understanding the potential intrapersonal conflict.

    Science.gov (United States)

    Subhi, Nasrudin; Geelan, David

    2012-01-01

    Reconciling sexual orientation with religious and spiritual beliefs can be challenging for Christian homosexuals, since many Christian churches teach that homosexual behavior is sinful. A qualitative study of 10 male and 10 female Christian homosexuals was conducted via semistructured interviews. This article seeks to explore the potential conflict between Christianity and homosexuality faced by the respondents. Participants' life stories and experiences varied widely. A few respondents were unaffected by the potential conflict between Christianity and homosexuality, however, the majority were affected. Effects included depression, guilt, anxiety, suicidal ideation, and alienation. Implications of the findings for support personnel are included.

  14. Homophobia and perceptions about homosexuality among students ...

    African Journals Online (AJOL)

    Both male and female same-sex sexual activity is illegal in Nigeria.2 Discrimination by reason of sexual orientation, termed homophobia, embraces prejudices against LGBT individuals. The objective of the study was to determine the prevalence of homophobia, explore the perception about homosexuality and associations ...

  15. What Is A Homosexual? A Definitional Model.

    Science.gov (United States)

    Berger, Raymond M.

    1983-01-01

    Presents a definitional model to explain homosexuality and discusses its implications for practice. Contends that social workers must discard the traditional binary model of hetersexual versus homesexual for one incorporating relevant psychosocial factors including life experiences, social reaction, and association with others. (Author/JAC)

  16. Acceptance of homosexuality in the Netherlands 2011

    NARCIS (Netherlands)

    Saskia Keuzenkamp

    2011-01-01

    The Dutch government wishes to promote the social acceptance of homosexuality. To gain an impression of the current status and the progress in achieving this objective, the government asked the Netherlands Institute for Social Research/SCP to carry out a study of the current statistics and

  17. Homosexuality in Cameroon: identity and persecution

    NARCIS (Netherlands)

    Geschiere, P.; Dubel, I.; Hielkema, A.

    2010-01-01

    What does it mean to come out of the closet in Cameroon? It is clear that it takes courage, particularly lately, as the law has always expressly prohibited homosexuality. (1) The police, generally feared because of their brutal extortion of money from people, are eager to react to accusations of

  18. Acceptance of homosexuality in the Netherlands

    NARCIS (Netherlands)

    Lisette Kuyper; Floor Bakker

    2006-01-01

    Original title: De houding ten opzichte van homoseksualiteit. To date, relatively little systematic research has been carried out on public attitudes to homosexual men and women in the Netherlands - far less than in the United States, for example. SCP has recently carried out a large-scale

  19. Homosexual Identity in Alex Sanchez's 'Rainbow Trilogy'

    Directory of Open Access Journals (Sweden)

    Nanda Vidyastria

    2017-03-01

    Full Text Available This research aims at describing 1 stages of homosexual identity development in three main characters in the Rainbow Trilogy using Cass model, 2 factors influencing the development of homosexual identity using D Augellis theory, and 3 forms of victimization towards homosexuals experienced by the main characters using theories of D Augelli and Rivers. Queer studies was applied to describe and analyze the data in forms of words, phrases, sentences, statements, dialogues as well as monologues in the Rainbow Trilogy, recording thoughts and actions by the characters in accordance with the research focus. As a result, the research finds out that the three novels describe clearly all stages of Cass model of homosexual identity development in Jason and Kyle, including their identity confusions, comparisons, acceptances, tolerances, prides and syntheses. In Nelson, only one stage that can be identified as Nelson is described as one whose sexual identity has been formed. The research also reveals how factors of personal subjectivity and action, interactive intimacy and sociohistorical connection are connected to each others and also influencing the homosexual identity developments of the main characters. Besides, the research also shows that various kinds of victimization occur to Jason, Kyle and Nelson. Normative victimizations made to feel different are experienced by Nelson and Kyle. Family stressor and prejudices in connection to AIDS are experienced by the three characters. Victimization of direct attacks in forms of verbal and physical abuses are experienced by Kyle and Nelson. Lastly, the research finds out that Nelson is the only character experiencing sexual abuse. It occurs in form of undesired comments oriented to a sexual violence.

  20. Social norms and prejudice against homosexuals.

    Science.gov (United States)

    Pereira, Annelyse; Monteiro, Maria Benedicta; Camino, Leoncio

    2009-11-01

    Different studies regarding the role of norms on the expression of prejudice have shown that the anti-prejudice norm influences people to inhibit prejudice expressions. However, if norm pressure has led to a substantial decrease in the public expression of prejudice against certain targets (e.g., blacks, women, blind people), little theoretical and empirical attention has been paid to the role of this general norm regarding sexual minorities (e.g., prostitutes, lesbians and gays). In this sense, the issue we want to address is whether general anti-prejudice norms can reduce the expression of prejudice against homosexual individuals. In this research we investigate the effect of activating an anti-prejudice norm against homosexuals on blatant and subtle expressions of prejudice. The anti-prejudice norm was experimentally manipulated and its effects were observed on rejection to intimacy (blatant prejudice) and on positive-negative emotions (subtle prejudice) regarding homosexuals. 136 university students were randomly allocated to activated-norm and control conditions and completed a questionnaire that included norm manipulation and the dependent variables. A multivariate analysis of variance (MANOVA) as well as subsequent ANOVAS showed that only in the high normative pressure condition participants expressed less rejection to intimacy and less negative emotions against homosexuals, when compared to the simple norm-activation and the control conditions. Positive emotions, however, were similar both in the high normative pressure and the control conditions. We concluded that a high anti-prejudice pressure regarding homosexuals could reduce blatant prejudice but not subtle prejudice, considering that the expression of negative emotions decreased while the expression of positive emotions remained stable.

  1. Extra-Articular Manifestations of Seronegative and Seropositive Rheumatoid Arthritis

    Directory of Open Access Journals (Sweden)

    Vjollca Sahatçiu-Meka

    2010-02-01

    Full Text Available Although considered a “joint disease,” rheumatoid arthritis is associated with the involvement of extra-articular manifestations. The aim of the study is the investigation and comparison of frequency and type of extra-articular manifestations in a well defined community based cohort of patients with seropositive and seronegative rheumatoid arthritis. Using the ACR (1987 criteria for rheumatoid arthritis, patients have been classified into the 2nd and 3rd functional class (ARA. The studied group consisted of 125 seronegative patients with titters lower than 1:64 as defined by Rose-Waaler test, whereas the control group consisted of 125 seropositive patients with titters of 1:64 or higher. All patients were between 25-60 years of age (Xb=49,96, with disease duration between 1-27 years (Xb=6,41. In order to present the findings of the study, the structure, prevalence, arithmetic mean (Xb, standard deviation (SB, variation quotient (QV% and variation interval (Rmax-Rmin have been used. Probability level has been expressed by p<0,01 and p<0,05. Correlation between the number of extra-articular manifestations and duration of the disease has been calculated by means of Pearson linear correlation. Higher presence of diffuse lung fibrosis, central and peripheral nervous system damages have been confirmed in the seropositive group, and osteoporosis in the seronegative; however, no statistical difference has been found. In extra-articular manifestations, “rheumatoid core” in the seropositive subset (χ2=4,80, p<0,05 presented significant statistical difference. Rheumatoid nodules were more frequent in seropositive subset (12%:16%, in both sexes; however, they were not of significant statistical difference. Neuropathy and lung diseases were also frequently present in seropositive group, but no statistical difference has been found regarding the statistical difference. Longer duration of the disease resulted in an increase of the number of extra

  2. Extra-articular manifestations of seronegative and seropositive rheumatoid arthritis.

    Science.gov (United States)

    Sahatciu-Meka, Vjollca; Rexhepi, Sylejman; Manxhuka-Kerliu, Suzana; Rexhepi, Mjellma

    2010-02-01

    Although considered a "joint disease," rheumatoid arthritis is associated with the involvement of extra-articular manifestations. The aim of the study is the investigation and comparison of frequency and type of extra-articular manifestations in a well defined community based cohort of patients with seropositive and seronegative rheumatoid arthritis. Using the ACR (1987) criteria for rheumatoid arthritis, patients have been classified into the 2nd and 3rd functional class (ARA). The studied group consisted of 125 seronegative patients with titters lower than 1:64 as defined by Rose-Waaler test, whereas the control group consisted of 125 seropositive patients with titters of 1:64 or higher. All patients were between 25-60 years of age (Xb=49,96), with disease duration between 1-27 years (Xb=6,41). In order to present the findings of the study, the structure, prevalence, arithmetic mean (Xb), standard deviation (SB), variation quotient (QV%) and variation interval (Rmax-Rmin) have been used. Probability level has been expressed by p<0,01 and p<0,05. Correlation between the number of extra-articular manifestations and duration of the disease has been calculated by means of Pearson linear correlation. Higher presence of diffuse lung fibrosis, central and peripheral nervous system damages have been confirmed in the seropositive group, and osteoporosis in the seronegative; however, no statistical difference has been found. In extra-articular manifestations, "rheumatoid core" in the seropositive subset (chi2=4,80, p<0,05) presented significant statistical difference. Rheumatoid nodules were more frequent in seropositive subset (12%:16%), in both sexes; however, they were not of significant statistical difference. Neuropathy and lung diseases were also frequently present in seropositive group, but no statistical difference has been found regarding the statistical difference. Longer duration of the disease resulted in an increase of the number of extra

  3. An Overview. High Risk Series.

    Science.gov (United States)

    General Accounting Office, Washington, DC.

    This report provides an overview of efforts undertaken by the U.S. General Accounting Office (GAO) in 1990 to review and report on federal program areas its work identified as high risk because of vulnerabilities to waste, fraud, abuse, and mismanagement. It reviews the current status of efforts to address these concerns. The six categories of…

  4. Medical students and interns’ knowledge about and attitude towards homosexuality

    Science.gov (United States)

    Banwari, G; Mistry, K; Soni, A; Parikh, N; Gandhi, H

    2015-01-01

    Background and Rationale: Medical professionals’ attitude towards homosexuals affects health care offered to such patients with a different sexual orientation. There is absence of literature that explores the attitudes of Indian medical students or physicians towards homosexuality. Aim: This study aimed to evaluate Indian medical students and interns’ knowledge about homosexuality and attitude towards homosexuals. Materials and Methods: After IEC approval and written informed consent, a cross-sectional study was conducted on a purposive sample of undergraduate medical students and interns studying in one Indian medical college. The response rate was 80.5%. Only completely and validly filled responses (N = 244) were analyzed. The participants filled the Sex Education and Knowledge about Homosexuality Questionnaire (SEKHQ) and the Attitudes towards Homosexuals Questionnaire (AHQ). SEKHQ consisted of 32 statements with response chosen from ‘true’, ‘false’, or ‘don’t know’. AHQ consisted of 20 statements scorable on a 5-point Likert scale. Multiple linear regression was used to find the predictors of knowledge and attitude. Results: Medical students and interns had inadequate knowledge about homosexuality, although they endorsed a neutral stance insofar as their attitude towards homosexuals is concerned. Females had more positive attitudes towards homosexuals. Knowledge emerged as the most significant predictor of attitude; those having higher knowledge had more positive attitudes. Conclusion: Enhancing knowledge of medical students by incorporation of homosexuality related health issues in the curriculum could help reduce prejudice towards the sexual minority and thus impact their future clinical practice. PMID:25766341

  5. Medical students and interns' knowledge about and attitude towards homosexuality.

    Science.gov (United States)

    Banwari, G; Mistry, K; Soni, A; Parikh, N; Gandhi, H

    2015-01-01

    Medical professionals' attitude towards homosexuals affects health care offered to such patients with a different sexual orientation. There is absence of literature that explores the attitudes of Indian medical students or physicians towards homosexuality. This study aimed to evaluate Indian medical students and interns' knowledge about homosexuality and attitude towards homosexuals. After IEC approval and written informed consent, a cross-sectional study was conducted on a purposive sample of undergraduate medical students and interns studying in one Indian medical college. The response rate was 80.5%. Only completely and validly filled responses (N = 244) were analyzed. The participants filled the Sex Education and Knowledge about Homosexuality Questionnaire (SEKHQ) and the Attitudes towards Homosexuals Questionnaire (AHQ). SEKHQ consisted of 32 statements with response chosen from 'true', 'false', or 'don't know'. AHQ consisted of 20 statements scorable on a 5-point Likert scale. Multiple linear regression was used to find the predictors of knowledge and attitude. Medical students and interns had inadequate knowledge about homosexuality, although they endorsed a neutral stance insofar as their attitude towards homosexuals is concerned. Females had more positive attitudes towards homosexuals. Knowledge emerged as the most significant predictor of attitude; those having higher knowledge had more positive attitudes. Enhancing knowledge of medical students by incorporation of homosexuality related health issues in the curriculum could help reduce prejudice towards the sexual minority and thus impact their future clinical practice.

  6. Perceptions & Attitudes of Male Homosexuals from Differing Socio-Cultural & Audiological Backgrounds.

    Science.gov (United States)

    Swartz, Daniel B.

    This study examined four male homosexual, sociocultural groups: normal-hearing homosexuals with normal-hearing parents, deaf homosexuals with normal-hearing parents, deaf homosexuals with hearing-impaired parents, and hard-of-hearing homosexuals with normal-hearing parents. Differences with regard to self-perception, identity, and attitudes were…

  7. Investigating the Islamic Perspective on Homosexuality.

    Science.gov (United States)

    Jahangir, Junaid B; Abdul-Latif, Hussein

    2016-07-01

    In his 2006 article in the Journal of the Islamic Medical Association of North America (JIMA), Dr. Ahmed qualified the predominant psychiatric view on homosexuality by recourse to opinions prevalent within reparative therapy circles. Conservative Muslim thinkers, online counselors, and other professionals continue to hold opinions similar to those delineated by Dr. Ahmed in his journal article. We use his article as a focal point to critique the general opinions upheld by conservative Muslim thinkers by alluding to the harms associated with reparative therapy and by rejecting the unreasonable prescription of permanent celibacy. We critique Dr. Ahmed's association of homosexuality with mental health issues, fatal diseases, alcoholism, and illicit sexual intercourse. Investigating the Muslim tradition, we encourage conservative Muslim leaders to facilitate Muslim gays and lesbians in their legitimate human need for intimacy, affection, and companionship.

  8. THE DEPICTION OF HOMOSEXUALITY IN AMERICAN MOVIES

    OpenAIRE

    Rudy Rudy

    2016-01-01

    This study focuses on the depiction of homosexuality in American films. It is intended to identify the images of gays depicted in American films as well as the characteristics of American gay movies. It incorporates library research by applying an analytical descriptive approach in analyzing the data. The symbol and reflective theory is used to analyze 18 American movies and 14 gay films from other countries in the early 2000s. It shows that gay films can attract audiences by describing gays ...

  9. The Depiction Of Homosexuality In American Movies

    OpenAIRE

    Rudy, Rudy

    2016-01-01

    This study focuses on the depiction of homosexuality in American films. It is intended to identify the images of gays depicted in American films as well as the characteristics of American gay movies. It incorporates library research by applying an analytical descriptive approach in analyzing the data. The symbol and reflective theory is used to analyze 18 American movies and 14 gay films from other countries in the early 2000s. It shows that gay films can attract audiences by describing gays ...

  10. Clinical high risk for psychosis

    DEFF Research Database (Denmark)

    van der Steen, Y; Gimpel-Drees, J; Lataster, T

    2017-01-01

    OBJECTIVE: The aim of this study was to assess associations between momentary stress and both affective and psychotic symptoms in everyday life of individuals at clinical high risk (CHR), compared to chronic psychotic patients and healthy controls, in search for evidence of early stress...... and 26 healthy controls. RESULTS: Multilevel models showed significantly larger associations between negative affect (NA) and activity-related stress for CHR patients than for psychotic patients (P = 0.008) and for CHR compared to controls (P

  11. Gender-related factors influencing perceptions of homosexuality.

    Science.gov (United States)

    Wong, F Y; McCreary, D R; Carpenter, K M; Engle, A; Korchynsky, R

    1999-01-01

    There is a long history linking gender role conformity to perceived homosexuality. However, the lack of a systematic theoretical model hinders the elucidation of the interrelationships among gender stereotypes, conformity to gender stereotypes, and perceived homosexuality, as well as other factors which may mediate these relationships. The purpose of the present study was to propose such a model by combining theories of gender stereotype formation and maintenance with research investigating perceptions of homosexuality. Specifically, this study examined college students' perceptions of gender role characteristics in male and female adult target persons and these students' perceptions of the likelihood that the targets were homosexual. Path analysis demonstrated that the sex and occupation of the target person were significantly related to perceived masculinity, femininity, and homosexuality of the target person. Furthermore, individual differences in these relationships were observed, indicating that the sex and gender role characteristics of the participant influenced perceptions of the gender role attributes and homosexuality of the target person.

  12. Theoretical perspectives accounting for adolescent homosexuality.

    Science.gov (United States)

    Savin-Williams, R C

    1988-03-01

    Few topics in sexology elicit such a diversity of opinions and emotions as the question of etiology of homosexuality. Views frequently carry with them implicit or explicit messages concerning the psychologic health of this sexual orientation. Theories of sexual development usually portray adolescence as a critical time in the life course because of changes in: 1) anatomy and physiology; 2) psychologic functioning: the reawakening, renewal, and reliving of previously established sexual relations and drives; and/or 3) social conditions: an increased exposure and adherence to societal messages concerning appropriate and inappropriate social and sexual behaviors and relationships. This paper provides a brief overview of several major theories--evolutionary biology, psychoanalysis, and social processes--as they relate to the development of sexual orientation. In addition, an ethologic perspective that synthesizes various etiologic theories, as they relate to homosexuality during adolescence, is briefly reviewed. In these discussions, the issue of whether homosexuality is a normal or abnormal developmental state during adolescence is also addressed.

  13. Towards a further understanding of prenatal thyroid theory of homosexuality: Autoimmune thyroiditis, polycystic ovary syndrome, autism and low birth weight

    Directory of Open Access Journals (Sweden)

    Osman Sabuncuoglu

    2017-10-01

    Full Text Available Research into the neurobiological origins of same-sex attraction is inconclusive. A recent theory of homosexuality posited that maternal thyroid dysfunction during pregnancy is associated with an increased rate of homosexual orientation in offspring. Relevant studies from the prenatal thyroid model perspective were reviewed, the major findings of which are as follows: i An increased prevalence of Hashimoto’s disease in lesbian women suggests a maternal and even familial presence of the same autoimmune thyroid disease. Female-tomale transsexuals and lesbian women were also reported to have higher rates of polycystic ovary syndrome (PCOS. Over the last several years, reports suggesting a strong link between PCOS and thyroid autoimmunity have accumulated. ii The increased risk of autism spectrum disorders (ASD in the offspring of mothers with thyroid autoimmunity in pregnancy and the association between ASD and gender dysphoria indicate a link between maternal thyroid dysfunction and gender dysphoria/same-sex attraction in the offspring. iii The high risk of miscarriage and retarded fetal growth in pregnancies of mothers who give birth to homosexual offspring can be explained by the impact of maternal thyroid dysfunction during pregnancy. This perspective review highlights relevant research findings and integrates them into the prenatal thyroid model of homosexuality. A better understanding of the mechanisms involved in the generation of same-sex orientation will contribute to the betterment of individual lives, as well as of society.

  14. Neuroendocrine mechanisms and the aetiology of male and female homosexuality.

    Science.gov (United States)

    MacCulloch, M J; Waddington, J L

    1981-10-01

    Theories on the classification and aetiology of male homosexuality are reviewed, particularly recent hypotheses on the role of prenatal hormonal influences on brain sexual differentiation and subsequent sexual object choice in the male. Female as well as male brain sexual differentiation may be hormonally determined, and so primary homosexuality in both sexes may be due to abnormalities in foetal exposure to hormones, leading first to physical mis-differentiation and later to homosexual behaviour in genetically and phenotypically normal men and women.

  15. Scrutinizing Homophobia: A Model of Perception of Homosexuals in Russia.

    Science.gov (United States)

    Gulevich, Olga A; Osin, Evgeny N; Isaenko, Nadezhda A; Brainis, Lilia M

    2017-10-10

    We aimed to develop and validate a model of associations of perceived threat of homosexuals with lay beliefs about causes of homosexuality, group entitativity of homosexuals, approval of social action strategies targeting homosexuals, and support for their rights using original Russian-language measures. We tested the model in two samples of social network users (n = 1,007) and student respondents (n = 292) using structural equation modeling and path analysis. Attribution of homosexuality to social causes was a positive predictor of perceived threat of homosexuals, whereas biological causes showed an inverse effect. Perceived threat predicted approval of discriminatory strategies targeting homosexuals and lack of support for their rights and fully mediated the effects of causal beliefs on these variables. Group entitativity of homosexuals was a positive predictor of perceived threat and a significant moderator of its effects on support for punishment and medical treatment of homosexuals. We discuss the findings with reference to the Russian social context.

  16. The multifactorial nature of human homosexual behavior: A brief review

    Directory of Open Access Journals (Sweden)

    Barona, Daniel

    2014-12-01

    Full Text Available Homosexual behavior has been analyzed as an evolutionary paradox in the biological context. In this review, we will try to compile the main genetic, epigenetic, hormonal, neurological and immune explanations of homosexuality, as well as the ultimate evolutionary causes of this complex behavior in the human being, incorporating information from studies in other animal species. All these factors determine the homosexual behavior, acting most of the times, simultaneously. Hereditary and non hereditary factors determine homosexual behavior, explaining its persistence despite its apparent disadvantages in relation to reproductive fitness.

  17. [Homosexual parenthood and child development: present data].

    Science.gov (United States)

    Fond, G; Franc, N; Purper-Ouakil, D

    2012-02-01

    The aim of this article is to provide an overview of existing studies on gay and lesbian parenthood and child development. Although 200,000 to 300,000 children could be concerned in 2010 in France, there is a lack of research on this issue in our country. Research among children raised by homosexual parents involves methodological issues, such as defining homosexual families, sampling cases and controls, and choosing structured or semi-structured evaluations. The fact that homosexual marriage, adoption and insemination are not presently legal in France could explain that only one study has been conducted in France in 2000 among 58 children raided by homosexual parents. This study concluded that these children did not show an increased rate of behavior or anxiety disorders. Concerns about lesbian parenting have focused on the absence of a father, the homosexual orientation of the mother, and their negative consequences on the development of the children. Research on parenting and child rearing has repeatedly compared lesbian and heterosexual families, and in the last 30 years a growing body of studies on lesbian parents and the development of their children has been published. Studies about child development, sexual orientation, gender identity, gender role behavior, emotional/behavioral development, social relationships and cognitive functioning showed no difference between children of lesbian mothers and those of heterosexual parents. Likewise, parental functioning, the mothers' psychological health and maternal skills were not significantly different among lesbian mothers than among heterosexual mothers. In studies concerning gay fathers, findings generally indicate no differences in sexual orientation, socialization, or psychological outcomes in children of gay fathers compared to children of heterosexual fathers. However, the first study on the adult attachment style dimensions of adult women who had gay or bisexual fathers suggested that they were

  18. Representations of homosexuality and prejudice against homosexuals of college students in a course in biology education in Mozambique

    OpenAIRE

    Nota, Juvencio Manuel

    2014-01-01

    This article analyzes the representations (explanations) of future biology teachers about the nature of homosexuality and the type of prejudice expressed against homosexuals. For this we applied questionnaires to 127 students of both sexes from first to fourth year biology course in Pedagogical University in Maputo. The results showed a bipolar representation of homosexuality reasoned explanations psychosocial and biological, but also a widespread prejudice. The analysis of the type of anchor...

  19. A Mediational Model Explaining the Connection Between Religiosity and Anti-Homosexual Attitudes in Italy: The Effects of Male Role Endorsement and Homosexual Stereotyping.

    Science.gov (United States)

    Piumatti, Giovanni

    2017-01-01

    This study aimed to better understand the relationship between religiosity and anti-homosexual attitudes in Italy by examining the mediation effects of male role endorsement and homosexual stereotyping. A sample of 5,522 Italian residents (age range = 18-74) was drawn from a cross-sectional national representative survey carried out in 2011. Measures included general religiosity, male role endorsement, homosexual stereotyping, social acceptance of homosexuality, and homosexual rights endorsement. Structural equation modeling was used to test the mediational effects of male role endorsement and homosexual stereotyping on the relationship between general religiosity and attitudes toward lesbians and gay men. Results showed that both male role endorsement and homosexual stereotyping partially mediated the relationship. In a model where religiosity and both mediators positively explained anti-homosexual attitudes, male role endorsement was the strongest mediator. Endorsement of gender role beliefs and homosexual stereotyping may thus exacerbate the connection between religiosity and anti-homosexual attitudes among Italians.

  20. IgG4-Seronegative Autoimmune Pancreatitis and Sclerosing Cholangitis

    Directory of Open Access Journals (Sweden)

    Allon Kahn

    2015-01-01

    Full Text Available IgG4-related disease is a relatively novel clinical entity whose gastrointestinal manifestations include type 1 autoimmune pancreatitis (AIP and IgG4-associated sclerosing cholangitis. The presence of elevated serum IgG4 is suggestive but not essential for the diagnosis of type 1 AIP and is a pervasive feature of the proposed diagnostic criteria. The differential diagnosis of type 1 AIP includes malignant conditions, emphasizing the importance of a deliberate, comprehensive evaluation. Management of patients with a suggestive clinical presentation, but without serum IgG4 elevation, is difficult. Here we present three cases of IgG4-seronegative AIP and sclerosing cholangitis that responded to empiric steroid therapy and discuss approach considerations. These cases demonstrate the value of meticulous application of existing diagnostic algorithms to achieve a clinical diagnosis and avoid surgical intervention.

  1. Neuromyelitis optica: a positive appraisal of seronegative cases.

    Science.gov (United States)

    Bernard-Valnet, R; Liblau, R S; Vukusic, S; Marignier, R

    2015-12-01

    Neuromyelitis optica (NMO) is a rare inflammatory disorder of the central nervous system. The hallmark of NMO is the presence of specific autoantibodies directed against aquaporin 4 (AQP4-IgG). AQP4-IgG, included in diagnostic criteria, has enlarged the clinical spectrum of NMO and serves to predict relapses. Moreover AQP4-IgG has provided unprecedented insight in the immunopathology of NMO, representing a rationale for therapeutic intervention with relevant novel treatment strategies specific for NMO. However, some patients remain seronegative for AQP4-IgG despite a definite diagnosis of NMO and the use of the finest methods for antibody detection. Interestingly, seronegative NMO (NMO(neg)) patients exhibit different demographic and disease-related characteristics in comparison to seropositive patients. The recent association with autoantibodies specific for myelin oligodendrocyte glycoprotein (MOG) is the main indication that disease mechanisms might differ in NMO(pos) and NMO(neg), challenging the position of NMO(neg) patients in the spectrum of demyelinating diseases and therapeutic strategies to be adopted. Thus, a reappraisal of the NMO(neg) population is needed to improve NMO care. Here the current knowledge regarding NMO(neg) is reviewed and hypotheses on its pathogenesis are made including a comprehensive description of detection methods and the prevalence of AQP4-IgG and a review of the epidemiological, clinical and paraclinical characteristics of NMO(neg); finally an integrated view of the general pathophysiological mechanisms underlying NMO(neg) is provided. © 2015 EAN.

  2. Heart transplant outcomes in recipients of Centers for Disease Control (CDC) high risk donors.

    Science.gov (United States)

    Tsiouris, Athanasios; Wilson, Lynn; Sekar, Rajesh B; Mangi, Abeel A; Yun, James J

    2016-12-01

    A lack of donor hearts remains a major limitation of heart transplantation. Hearts from Centers for Disease Control (CDC) high-risk donors can be utilized with specific recipient consent. However, outcomes of heart transplantation with CDC high-risk donors are not well known. We sought to define outcomes, including posttransplant hepatitis and human immunodeficiency virus (HIV) status, in recipients of CDC high-risk donor hearts at our institution. All heart transplant recipients from August 2010 to December 2014 (n = 74) were reviewed. Comparison of 1) CDC high-risk donor (HRD) versus 2) standard-risk donor (SRD) groups were performed using chi-squared tests for nominal data and Wilcoxon two-sample tests for continuous variables. Survival was estimated with Kaplan-Meier curves. Of 74 heart transplant recipients reviewed, 66 (89%) received a SRD heart and eight (11%) received a CDC HRD heart. We found no significant differences in recipient age, sex, waiting list 1A status, pretransplant left ventricular assist device (LVAD) support, cytomegalovirus (CMV) status, and graft ischemia times (p = NS) between the HRD and SRD groups. All of the eight HRD were seronegative at the time of transplant. Postoperatively, there was no significant difference in rejection rates at six and 12 months posttransplant. Importantly, no HRD recipients acquired hepatitis or HIV. Survival in HRD versus SRD recipients was not significantly different by Kaplan-Meier analysis (log rank p = 0.644) at five years posttransplant. Heart transplants that were seronegative at the time of transplant had similar posttransplant graft function, rejection rates, and five-year posttransplant survival versus recipients of SRD hearts. At our institution, no cases of hepatitis or HIV occurred in HRD recipients in early follow-up. © 2016 Wiley Periodicals, Inc.

  3. Educating for Sexual Difference? Muslim Teachers' Conversations about Homosexuality

    Science.gov (United States)

    Sanjakdar, Fida

    2013-01-01

    Homosexuality is widely perceived among many Muslims as a "western disease", a natural outcome of the West's secularity and cultural degeneracy. In spite of the emergence of more liberal attitudes towards sexual differences in modern times, moral issues have not lost their relevance in polemical discourse against homosexuality among many…

  4. Intergroup Contact and Beliefs about Homosexuality in Adolescence

    Science.gov (United States)

    Heinze, Justin E.; Horn, Stacey S.

    2009-01-01

    This study examines the relationship between intergroup contact and adolescents' attitudes regarding homosexuality and the treatment of lesbian and gay (LG) peers. Fourteen- through 18-year-olds (n = 1,069, 59.7% females) completed self-report attitude and judgment questionnaires about the acceptability of homosexuality, levels of comfort around…

  5. Homosexual Teachers in the Classroom: The Debate Continues

    Science.gov (United States)

    Rowe, Robert N.

    2006-01-01

    A few years ago a state legislator traveled throughout California to promote a referendum that would prohibit homosexuals from teaching in classrooms. Together with his companions, they said that allowing homosexuals to teach in the classroom would expose young people to the "wrong role models." In this article, the author shares his views on this…

  6. Social Inequality on the College Campus: A Consideration of Homosexuality

    Science.gov (United States)

    Lance, Larry M.

    2008-01-01

    Aversion to homosexuals for many in the American society comes close to a true phobia, as a persistent and irrational fear. National surveys investigating attitudes toward homosexual relations between adults reported a majority of those responding believed that such relations were wrong. Taken to an extreme, homophobia and antigay discrimination…

  7. Ghanaian perspectives on the present day dynamics of homosexuality

    African Journals Online (AJOL)

    Homosexuality has been an issue of controversy since time immemorial, and it elicits various reactions and attitude which are influenced by the type of societies, cultural and moral development or political situation. In recent times there has been serious controversy over the incidence of homosexuality in Ghana, with human ...

  8. The Natural Law Theory of Morality and the Homosexuality Debate ...

    African Journals Online (AJOL)

    Same sex relationship has recently been criticized by many not only on grounds of being immoral but also as a practice that erodes certain values attached to marriage and procreation in some African cultures. This paper examines the immorality or otherwise of homosexuality as an act. It argues that homosexual behaviour ...

  9. Homosexuality amongst migrant oil workers in the Niger Delta ...

    African Journals Online (AJOL)

    Aims: To determine the prevalence of homosexuality among migrant oil workers in Niger Delta. Methods: A prospective questionnaire – based study was conducted among migrant oil workers in the Niger Delta region of Nigeria. The design was to determine the prevalence of homosexuality in the workers in oil workers.

  10. Social skills to homosexuals: Program toward Inlusion

    Directory of Open Access Journals (Sweden)

    Yanais Gutiérrez Jorge

    2015-09-01

    Full Text Available Male homosexuality in Cuba has been se gregated by means of discrimination what , may hinde r the social interation of this people. The research has carried out problems with the self - esteem , the knowledge of the assertive rights, the preparation to confront the conflicts in the interpersonal rel ationships, the correct use of the extraverbal language and the capacity to vary and to sustain approaches depending on the circumstances . This investigation propose to carry out a Sociocultural Animation Program to develop social skills in 25 male homosex uals in our province as a way to get their social insertion .

  11. Parenting behaviors of homosexual and heterosexual fathers.

    Science.gov (United States)

    Bigner, J J; Jacobsen, R B

    1989-01-01

    Responses of 33 homosexual (gay) fathers were compared with those of 33 heterosexual (nongay) fathers on the Iowa Parent Behavior Inventory, an empirical measure of dimensions of parenting behavior. Gay fathers did not differ significantly from nongay fathers in their reported degree of involvement nor in intimacy level with children. Gay fathers tended to be more strict, more responsive to children's needs, and to provide reasons for appropriate behavior to children more consistently than nongay fathers. Several explanations are explored for these similarities and differences in parenting styles.

  12. "Physical attractiveness stereotype" and the attribution of homosexuality revisited.

    Science.gov (United States)

    Dunkle, J H; Francis, P L

    1996-01-01

    The present study investigated whether subjects would perceive male and female faces as homosexual based upon facial attractiveness while statistically controlling for facial masculinity/femininity. Also of interest was the extent to which the subjects' gender and attitudes toward homosexuality would influence their perceptions. Eighty undergraduates indicated how likely they thought it was that six male and six female faces were homosexual. The targets were also rated on attractiveness and masculinity/femininity. The present sample also completed the Index of Homophobia, the Bem Sex Role Inventory, the Attitude Toward Women Scale, a conservatism scale, and a demographic questionnaire. The subjects assigned higher homosexuality ratings to the unattractive males and females compared to their attractive counterparts. Gender of subject and attitudes toward homosexuality did not significantly affect evaluations.

  13. A Further Assessment of Blanchard’s Typology of Homosexual Versus Non-Homosexual or Autogynephilic Gender Dysphoria

    Science.gov (United States)

    Bockting, Walter; Mason, Mona; Hwahng, Sel; Rosenblum, Andrew; Macri, Monica; Becker, Jeffrey

    2010-01-01

    In a series of important but now highly controversial articles, Blanchard examined associations of sexual orientation and transvestic fetishism among male-to-female (MTF) transgender persons in Toronto, Canada. Transvestic fetishism was rare among the homosexuals but prevalent among the non-homosexuals. Subtypes of non-homosexual MTFs (heterosexual, bisexual, and asexual) were consistently high with regard to transvestic fetishism. Non-linear associations of a continuous measurement of sexual attraction to women (gynephilia) and transvestic fetishism were interpreted in terms of an etiological hypothesis in which transvestic fetishism interferes with the early development of heterosexuality. Blanchard concluded that homosexual versus non-homosexual sexual orientation is a dominant and etiologically significant axis for evaluating and understanding this population. We further assessed these findings among 571 MTFs from the New York City metropolitan area. Using the Life Chart Interview, multiple measurements of transvestic fetishism were obtained and classified as lifetime, lifecourse persistent, adolescent limited, and adult onset. Large (but not deterministic) differences in lifetime, lifecourse persistent, and adolescent limited transvestic fetishism were found between the homosexuals and non-homosexuals. Contrary to Blanchard, differences in transvestic fetishism were observed across subtypes of the non-homosexuals, and linear (not curvilinear) associations were found along a continuous measurement of gynephilia and transvestic fetishism. Age and ethnicity, in addition to sexual orientation, were found to be statistically significant predictors of transvestic fetishism. The clinical, etiological, and sociopolitical implications of these findings are discussed. PMID:20039113

  14. Disapproval of Homosexuality : Comparative Research on Individual and National Determinants of Disapproval of Homosexuality in 20 European Countries

    NARCIS (Netherlands)

    van den Akker, Hanneke; van der Ploeg, Rozemarijn; Scheepers, Peer

    2013-01-01

    In this contribution, we elaborate on disapproval of homosexuality in 20 European countries. We mainly focus on the explanation of differences in the disapproval of homosexuality at the individual and the national level. Data from four waves of the European Social Survey are used, using multilevel

  15. Disapproval of Homosexuality: Comparative Research on Individual and National Determinants of Disapproval of Homosexuality in 20 European Countries

    NARCIS (Netherlands)

    Akker, H.M. van den; Ploeg, R. van der; Scheepers, P.L.H.

    2013-01-01

    In this contribution, we elaborate on disapproval of homosexuality in 20 European countries. We mainly focus on the explanation of differences in the disapproval of homosexuality at the individual and the national level. Data from four waves of the European Social Survey are used, using multilevel

  16. Homosexual Cohabitees Act, 18 June 1987.

    Science.gov (United States)

    1989-01-01

    The purpose of this Act is to place homosexual cohabitees in the same legal position as heterosexual cohabitees. It provides that if 2 persons are living together in a homosexual relationship, the following legal provisions relating to cohabitation shall apply to them: 1) the Cohabitees (Joint Homes) Act (1987:232), 2) the Inheritance Code, 3) the Real Property Code, 4) Chapter 10, section 9, of the Code of Judicial Procedure, 5) Chapter 4, section 19, 1st paragraph, of the Code of Execution, 6) section 19, 1st paragraph, section 35, subsection 4, and point 2a, 7th paragraph, of the regulations relating to Section 36 of the Municipal Tax Act (1928:370), 7) the Inheritance and Gift Taxes Act (1941:416), 8) Section 6 of the Court Procedures (Miscellaneous Business) Act (1946:807), 9) the Tenant Owner Act (1971:479), 10) section 10 of the Legal Aid Act (1972:429), and 11) the Notice to Unknown Creditors Act (1981:131).

  17. Teachers' attitudes and beliefs about homosexuality.

    Science.gov (United States)

    Pérez-Testor, Carles; Behar, Julia; Davins, Montse; Conde Sala, José Luís; Castillo, José A; Salamero, Manel; Alomar, Elisabeth; Segarra, Sabina

    2010-05-01

    Schools play a key role in transmitting attitudes towards sexual diversity. Many studies stress the importance of teachers' and other professionals' attitudes towards gay men and/or lesbian women. This study evaluates attitudes and prejudices toward homosexuality in a sample of 254 elementary and high school teachers in Barcelona and its surrounding area. The results obtained using a scale of overt and subtle prejudice and a scale of perceived discrepancy of values indicate that discrepancy between likely behavior and personal values was significantly greater in women, those who hold religious beliefs, churchgoers and people without any gay or lesbian acquaintances. Approximately 88% of the teachers showed no type of prejudiced attitudes towards gay men and lesbian women. The experience of proximity to gay men and/or lesbian women reduces not only the discrepancy between personal values and likely behavior but also the presence of homophobic prejudice. It would be advisable to expand specific teacher training in the subject of sexual diversity in order to reduce prejudicial attitudes, thus fostering non-stereotyped knowledge of homosexuality.

  18. Anti-homosexual prejudice . . . as opposed to what? Queer theory and the social psychology of anti-homosexual attitudes.

    Science.gov (United States)

    Hegarty, Peter; Massey, Sean

    2006-01-01

    This article uses Sedgwick's distinction between minoritizing and universalizing theories of sexuality to analyze variability in social psychologists' studies of anti-homosexual prejudice, focusing on studies of attitudes. Anti-homosexual prejudice was initially defined in conversation with gay liberationists and presumed, among other things, that fear of homoerotic potential was present in all persons. Later social psychologists theorized anti-homosexual prejudice in strict minoritizing terms: as prejudice towards a distinct out-group. In the first section of this paper we discuss corresponding shifts in the conceptualization of anti-homosexual attitudes. Next, using a universalizing framework, we re-interpret experiments on behavioral aspects of anti-homosexual attitudes which were originally conceptualized using a minoritizing framework, and suggest avenues for future research. Finally, we examine how queer theory might enrich this area of social psychological inquiry by challenging assumptions about the politics of doing scientific work and the utility of identity-based sexual politics.

  19. Sex Differences in Attitudes toward Homosexual Persons, Behaviors, and Civil Rights: A Meta-analysis.

    Science.gov (United States)

    Kite, Mary E.; Whitley, Bernard E., Jr.

    1996-01-01

    Used meta-analytic techniques to compare men's and women's attitudes toward homosexual persons, homosexual behaviors, and gay people's civil rights. As expected, size of sex differences varied across these categories. Men were more negative than women toward homosexual persons and homosexual behavior, but the sexes viewed gay civil rights…

  20. Seronegative Herpes simplex Associated Esophagogastric Ulcer after Liver Transplantation

    Directory of Open Access Journals (Sweden)

    Edouard Matevossian

    2008-03-01

    Full Text Available Herpes simplex infection is characterized by acute or subacute infection, often followed by a chronic carrier state. Consecutive recurrences may flare up if immunocompromise occurs. Herpes simplex associated esophagitis or duodenal ulcer have been reported in immunocompromised patients due to neoplasm, HIV/AIDS or therapeutically induced immune deficiency. Here we report the case of an HSV-DNA seronegative patient who developed grade III dysphagia 13 days after allogeneic liver transplantation. Endoscopy revealed an esophageal-gastric ulcer, and biopsy histopathology showed a distinct fibroplastic and capillary ulcer pattern highly suspicious for viral infection. Immunohistochemistry staining revealed a distinct nuclear positive anti-HSV reaction. Antiviral therapy with acyclovir and high-dose PPI led to a complete revision of clinical symptoms within 48 h. Repeat control endoscopy after 7 days showed complete healing of the former ulcer site at the gastroesophageal junction. Although the incidence of post-transplantation Herpes simplex induced gastroesophageal disease is low, the viral HSV ulcer may be included into a differential diagnosis if dysphagia occurs after transplantation even if HSV-DNA PCR is negative.

  1. Comparative brain pathology of HIV-seronegative and HIV-infected drug addicts.

    Science.gov (United States)

    Makrigeorgi-Butera, M; Hagel, C; Laas, R; Puschel, K; Stavrou, D

    1996-01-01

    Early stages of infection with human immunodeficiency virus (HIV) were studied in HIV-seropositive drug addicts. Since heroin users are immunocompromized even in the absence of HIV infection, the aim of the present study was to compare the morphological alterations present in HIV-seronegative and HIV-seropositive drug addicts. A total of 60 cases (32 HIV-seronegative subjects, 21 HIV-seropositive patients without signs of acquired immunodeficiency syndrome (AIDS), and 7 HIV-seropositive patients with signs of AIDS) were investigated macroscopically, histologically, and immunohistochemically HIV-seronegative patients presented more frequently with acute drug intoxication, died at a significantly younger age than HIV-seropositive patients, and were found to suffer more frequently from alcohol-related changes. These results indicated that HIV-seronegative and HIV-seropositive patients differed possibly in their drug consumption and also in their general conditions of life. In accordance with previous reports activated microglia and a diffuse astrogliosis in the white matter were detected at a significantly higher frequency and found to be more severe in HIV-seropositive subjects than in HIV-seronegative addicts. A lymphocytic meningitis was present in 6 of 21 HIV-seropositive patients but in none of the HIV-seronegative patients. Perivascular infiltrates consisting of lymphocytes and macrophages were detected at similar frequencies in HIV-seronegative and HIV-seropositive patients but were significantly more severe in patients suffering from lymphocytic meningitis or purulent encephalitis. Opportunistic infections were only demonstrated in 2 AIDS cases. In 10 of the HIV-seronegative patients and in 3 of the HIV-seropositive patients CD68-and Ham56-positive multinucleated cells were detected scattered in the subarachnoidal space exclusively over the frontal cortex.

  2. Sex hormones and female homosexuality: a critical examination.

    Science.gov (United States)

    Meyer-Bahlburg, H F

    1979-03-01

    To ascertain the validity of hormonal theories of human homosexuality, which are based on animal research, this article reviews psychoendocrine data on lesbian and transsexual women. Sex hormone levels were found to be normal in the majority of homosexual women, but about a third of the subjects studied had elevated androgen levels. In women with prenatal androgen excess, heterosexuality appears to be more frequent than bisexuality, and exclusive homosexuality is rare. Two recent reports suggest abnormalities of the neuroendocrine regulation of LH secretion in female transsexuals. Clearly, prenatal or postpubertal hormone levels do not determine the development of sexual orientation, but a facilitating neuroendocrine predisposition cannot be ruled out at present.

  3. [: an expert report by Dr. Egas Moniz on homosexuality].

    Science.gov (United States)

    Molina Artaloytia, Francisco

    2016-01-01

    At the beginning of the 20th century, the noted Nobel prize-winning Portuguese neurologist Egas Moniz made an expert analysis on homosexuality in a marriage annulment case of major value as an example of the effective application of sexological knowledge of that period. Contemporary republican legislation established marriage annulment in medical terms and punished relations between persons of the same sex, or contra natura. In his report, Moniz attempted to interpret distinctive elements of the life of the subject using sexological categories, illustrating the interaction between these categories and the changing forms adopted by homosexuality (or homosexual people) of the time.

  4. Conversion therapy for homosexuality: serious violation of ethics.

    Science.gov (United States)

    Patra, Suravi

    2016-01-01

    Across the world, homosexuality is gaining legitimacy; stigma and discrimination are gradually giving way to equality and inclusion. The situation in India is in stark contrast to these trends. In this country, homosexuality is an offence as per Section 377 of the IPC. The homosexual community is fighting for its rights and continues to suffer from intense stigma and discrimination. Their healthcare needs are not at all attended to; their sexual orientation is conceptualised as a socially deviant mental disease that needs psychiatric treatment.

  5. THE DEPICTION OF HOMOSEXUALITY IN AMERICAN MOVIES

    Directory of Open Access Journals (Sweden)

    Rudy Rudy

    2016-06-01

    Full Text Available This study focuses on the depiction of homosexuality in American films. It is intended to identify the images of gays depicted in American films as well as the characteristics of American gay movies. It incorporates library research by applying an analytical descriptive approach in analyzing the data. The symbol and reflective theory is used to analyze 18 American movies and 14 gay films from other countries in the early 2000s. It shows that gay films can attract audiences by describing gays as the objects for laughs; gays revealing their sexual identities; sexual scenes of gays; masculine gay men; and violence in gay life. They appear in genres like drama, comedy, romance, detective, western, and horror/mystery with two images of gay people shown in American gay movies; they are the portrait of gays as a minority and the pessimism. However, it also shows that some American gay films picture good gay life, happy gay couples, gay marriage, etc.

  6. Squamous cell carcinoma of the anus-an opportunistic cancer in HIV-positive male homosexuals

    Science.gov (United States)

    Gervaz, Pascal; Calmy, Alexandra; Durmishi, Ymer; Allal, Abdelkarim S; Morel, Philippe

    2011-01-01

    Squamous cell carcinoma of the anus (SCCA) is a common cancer in the human immunodeficiency virus (HIV)-infected population, and its incidence continues to increase in male homosexuals. Combined chemoradiation with mitomycin C and 5-fluorouracil was poorly tolerated by severely immunocompromised patients in the early 1990s. In the era of highly active antiretroviral therapy (HAART), however, recent data indicate that: (1) most HIV patients with anal cancer can tolerate standard chemotherapy regimens; and (2) this approach is associated with survival rates similar to those of HIV-negative patients. However, HIV-positive patients with SCCA are much younger, more likely to develop local tumor recurrence, and ultimately die from anal cancer than immune competent patients. Taken together, these findings suggest that anal cancer is an often fatal neoplasia in middle-aged HIV-positive male homosexuals. In this population, SCCA is an opportunistic disease resulting in patients with suboptimal immune function from persistent infection and prolonged exposition to oncogenic human papillomaviruses (HPVs). Large-scale cancer-prevention strategies (routine anuscopy and anal papanicolaou testing) should be implemented in this population. In addition, definitive eradication of oncogenic HPVs within the anogenital mucosa of high-risk individuals might require a proactive approach with repeated vaccination. PMID:21799644

  7. Excess of counterclockwise scalp hair-whorl rotation in homosexual ...

    Indian Academy of Sciences (India)

    Unknown

    Keywords. sexual orientation; homosexuality; human behaviour; hair-whorl orientation; behaviour biology. *E-mail: .... self-reporting gay men are obtained in follow-up studies. .... ous studies were limited to handedness determination, in.

  8. Study of Naval Officers' Attitudes Toward Homosexuals in the Military

    National Research Council Canada - National Science Library

    Hicknell, John

    2000-01-01

    This study examines the attitudes of Naval officers concerning homosexuals in the military, including trends in attitudes over the past six years and understanding of the "Don't Ask, Don't Tell" policy...

  9. A Discursive Psychological Analysis of Islamic Sermons on Homosexuality

    Directory of Open Access Journals (Sweden)

    Mohd Asyraf Zulkffli

    2016-11-01

    Full Text Available This paper aims to provide insights into the delivery of Islamic sermons in regards to homosexuality. The spoken discourse which constitutes data for this study were generated from the sermons delivered by two Malaysian preachers. These sermons were retrieved from the video sharing website, Youtube. The two preachers were chosen because of their popularity and huge following. The spoken discourse was analyzed using the Discursive Psychology (DP approach, more specifically, the Discursive Action Model (DAM proposed by Edwards and Potter (1992. The analysis shows that these preachers expertly employed DP strategies in maneuvering their sermons so that Islamic ruling on the sinfulness of homosexuality is unflinchingly delivered. At the same time the rest of the Muslim communities are urged to treat LGBT individuals humanely. This paper thus challenges the notions that Islam is inherently homophobic and that Muslims who believe that homosexuality is a sin would necessarily discriminate against homosexuals.

  10. GOOD HOMOSEXUAL BEHAVIOUR DECREASE PREVALENCE OF SEXUAL TRANSMITTED DISSEASE

    Directory of Open Access Journals (Sweden)

    Purwaningsih Purwaningsih

    2017-07-01

    Full Text Available Introduction: The homosexual behaviour were become indicators of sexually transmitted diseases’s (STDs prevalencies. Prevalence of sexually transmitted diseases in homosexual community was very high but until recently study it was conducted sporadically. The objective of this study was to analyze the correlation of homosexual behaviour with prevalence of sexually transmitted diseases (STDs in Mobile Clinic Community Centre of IGAMA collaborating with Public Health Centre Sumberpucung of Malang Regency. Method:  Analytic design with cross sectional methode was used in this study. The population were all visitors of Mobile Clinic Community Centre of IGAMA collaborating with Public Health Centre Sumberpucung of Malang Regency (353 people. Sample were 40 people who met to the inclusion criteria. The independent variable was homosexual behaviour and the dependent variable was prevalence of sexually transmitted diseases (STDs. Data for homosexual behaviour were collected by using questionnaire and indhept interview with content analyze and data for prevalence of sexually transmitted diseases (STDs were collected by using laboratorium test for STDs. Result: The research result was presented in the form diagram, table of cross tabulation and analyzed by using Spearman Rho with significance level ρ=0.005. The result showed that there was correlation of homosexual knowledge (ρ=0.001, attitude (ρ=0.000 and  practice (ρ=0.000 with prevalence of STDs. Dsicussion:  It can be concluded that the better knowledge, attitude and practice of homosexual could be decrease prevalence of STDs. Futher studies are recomended to analyze the correlation between homosexual behaviour and prevalence of STDs with Health Believe approach.

  11. Formation of homosexual orientation of men in adolescence

    Directory of Open Access Journals (Sweden)

    Katra Grażyna

    2014-09-01

    Full Text Available The aim of the study was to explore the experiences of homosexual men connected with the formation of their sexual orientation in adolescence. A comparative study of 27 young adult homosexual men and 28 heterosexual men of similar age used a categorised interview questionnaire consisting of two parts: the first with questions regarding sexual dreams, fantasies and erotic encounters; the second with questions on family and social circumstances.

  12. Explaining homosexuality: philosophical issues, and who cares anyhow?

    Science.gov (United States)

    Suppe, F

    1994-01-01

    Standard behavioral and biological attempts to explain the etiology of homosexuality are surveyed. These include genetic, physiological (e.g., hormonal), constitutional (e.g., wrong pubic hair configurations), childhood experience, parenting, and psychoanalytic accounts. These are criticized from a number of perspectives, including inadequate conceptualization of homosexuality and heterosexuality. The use of path analysis to assess etiological accounts is examined, with particular attention being paid to the Kinsey Institute's Sexual Preference efforts. Drawing from the sociology of science, recent philosophical work on the growth of scientific knowledge, and historical considerations, the legitimacy of homosexual etiology as a scientific research question is examined. It is argued that homosexual etiology is a degenerative research program. The research program's conceptual crudity with respect to sexual identity and sexual orientation precludes it from making any scientific contribution. Thus the claim that homosexual etiology is a legitimate scientific issue is plausible only against the background of a set of late Victorian normative assumptions about "normal love," some surrogate thereof, or a political agenda. Implications of the homosexuality etiology case study for more general philosophical treatments of explanation are considered briefly.

  13. Dismantling reified African culture through localised homosexualities in Uganda.

    Science.gov (United States)

    Nyanzi, Stella

    2013-01-01

    Uganda's Anti-Homosexuality Bill of 2009 aimed at protecting the cherished culture of the people against emergent threats to the traditional heterosexual family. The Bill's justification, however, lay in myopic imaginings of a homogenous African-ness and pedestrian oblivion to pluralities within African sexualities. This paper revisits the debate that homosexuality is 'un-African'. Rhetoric analysis of the Anti-Homosexuality Bill exposes how dominant discourses of law, medicine, religion, geography and culture reinforce the view that homosexuality is foreign to Africa. Based on ethnography in contemporary Uganda, I explore how self-identified same-sex-loving individuals simultaneously claim their African-ness and their homosexuality. Their strategies include ethnic belonging, membership to kinship structures, making connections with pre-colonial histories of homosexuality, civic participation in democratic processes, national identity, organising of lesbian, gay, bisexual, transgender, intersex and questioning support groups, language and nomenclature, visibility and voice in local communal activities, solidarity and adherence to cultural rituals. In present-day Uganda, same-sex-loving men, women and transgender people variously assert their African-ness.

  14. Christine Angot: una hetero-homosexual incestuosa

    Directory of Open Access Journals (Sweden)

    María José Palma Borrego

    2008-01-01

    Full Text Available El proyecto literario de Christine Angot en L’inceste (1999 es el de desvelar no su historia incestuosa –ella misma afirma que su libro no es una autobiografía– sino el hacer visible lo más reprimido, lo más oculto y a la vez lo más originario de nuestra Cultura: el incesto con la madre. Un incesto que puede ser real o imaginario, y que el trabajo de escritura desvela y configura sus territorios que van desde la fusión con la madre, característica de toda situación preedípica, hasta una relación homosexual real con su doble narcisista, pasando por el deseo incestuoso por su hija. Mundo sin castración en donde todo puede ser posible, en ese juego de “ser” y “no-ser”, y en donde la temática del incesto está representada en el texto por una espacialidad vertical, de arriba abajo, generacional, madre/hija-Christine-Léonore, y horizontal, Christine-Marie Christine.

  15. Brain response to visual sexual stimuli in homosexual pedophiles.

    Science.gov (United States)

    Schiffer, Boris; Krueger, Tillmann; Paul, Thomas; de Greiff, Armin; Forsting, Michael; Leygraf, Norbert; Schedlowski, Manfred; Gizewski, Elke

    2008-01-01

    The neurobiological mechanisms of deviant sexual preferences such as pedophilia are largely unknown. The objective of this study was to analyze whether brain activation patterns of homosexual pedophiles differed from those of a nonpedophile homosexual control group during visual sexual stimulation. A consecutive sample of 11 pedophile forensic inpatients exclusively attracted to boys and 12 age-matched homosexual control participants from a comparable socioeconomic stratum underwent functional magnetic resonance imaging during a visual sexual stimulation procedure that used sexually stimulating and emotionally neutral photographs. Sexual arousal was assessed according to a subjective rating scale. In contrast to sexually neutral pictures, in both groups sexually arousing pictures having both homosexual and pedophile content activated brain areas known to be involved in processing visual stimuli containing emotional content, including the occipitotemporal and prefrontal cortices. However, during presentation of the respective sexual stimuli, the thalamus, globus pallidus and striatum, which correspond to the key areas of the brain involved in sexual arousal and behaviour, showed significant activation in pedophiles, but not in control subjects. Central processing of visual sexual stimuli in homosexual pedophiles seems to be comparable to that in nonpedophile control subjects. However, compared with homosexual control subjects, activation patterns in pedophiles refer more strongly to subcortical regions, which have previously been discussed in the context of processing reward signals and also play an important role in addictive and stimulus-controlled behaviour. Thus future studies should further elucidate the specificity of these brain regions for the processing of sexual stimuli in pedophilia and should address the generally weaker activation pattern in homosexual men.

  16. The debate on homosexuality mediated by social representations: homosexual and heterosexual perspectives / O debate sobre a homossexualidade mediado por representações sociais: perspectivas homossexuais e heterossexuais

    Directory of Open Access Journals (Sweden)

    Anderson Scardua

    2006-01-01

    Full Text Available The objective of this work was to study the social representations of homosexuality among college students, according to sexual orientation and sex. One free association question about the word homosexuality and another about is possible causes were answered. The data was analyzed according to the principles of content analysis. There were significant differences among the groups, allowing us to find out different ways of understanding/dealing with homosexuality and facing prejudice/discrimination. The homosexual men publicly justified/legitimated (rights, freedom homosexuality with the argument/representation that it is uncontrollable/natural, while the homosexual women preferred to build and improve interaction agreements on the interpersonal level (family, love affair to obtain social recognition. Yet the heterosexual men and women, with many references to normality and others contents that reinforce the social conventions, pointed out less possibility of recognition towards homosexuality.

  17. Resuscitation of newborn in high risk deliveries

    International Nuclear Information System (INIS)

    Yousaf, U.F.; Hayat, S.

    2015-01-01

    High risk deliveries are usually associated with increased neonatal mortality and morbidity. Neonatal resuscitation can appreciably affect the outcome in these types of deliveries. Presence of personnel trained in basic neonatal resuscitation at the time of delivery can play an important role in reducing perinatal complications in neonates at risk. The study was carried out to evaluate the effects of newborn resuscitation on neonatal outcome in high risk deliveries. Methods: This descriptive case series was carried out at the Department of Obstetrics and Gynecology, Jinnah Hospital, Lahore. Ninety consecutive high risk deliveries were included and attended by paediatricians trained in newborn resuscitation. Babies delivered by elective Caesarean section, normal spontaneous vaginal deliveries and still births were excluded. Neonatal resuscitation was performed in babies who failed to initiate breathing in the first minute after birth. Data was analyzed using SPSS-16.0. Results: A total of 90 high risk deliveries were included in the study. Emergency caesarean section was the mode of delivery in 94.4% (n=85) cases and spontaneous vaginal delivery in 5.6% (n=5). Preterm pregnancy was the major high risk factor. Newborn resuscitation was required in 37.8% (n=34) of all high risk deliveries (p=0.013). All the new-borns who required resuscitation survived. Conclusion: New-born resuscitation is required in high risk pregnancies and personnel trained in newborn resuscitation should be available at the time of delivery. (author)

  18. Remitting seronegative symmetrical synovitis with pitting edema (RS3PE syndrome

    Directory of Open Access Journals (Sweden)

    Neslihan Gokcen

    2017-03-01

    Full Text Available Remitting seronegative symmetrical synovitis with pitting edema is a rare rheumatological disorder that presents with symmetrical hand and/or foot edema resembling rheumatoid arthritis. It is generally seen in male patients in older age, but atypical cases in different age groups have been documented. Although no clear mechanism has been described, certain genetic and environmental factors have been suggested for etiopathogenesis. Medical treatment is mainly focused on glucocorticoid therapy. This article aims to discuss the Remitting seronegative symmetrical synovitis with pitting edema syndrome and to review the current literature. [Cukurova Med J 2017; 42(1.000: 147-154

  19. Genetic and Environmental Influences on Individual Differences in Attitudes Toward Homosexuality: An Australian Twin Study.

    NARCIS (Netherlands)

    Verweij, K.J.H.; Shekar, S.N.; Zietsch, B.P.; Eaves, L.J.; Bailey, J.M.; Boomsma, D.I.; Martin, N.G.

    2008-01-01

    Previous research has shown that many heterosexuals hold negative attitudes toward homosexuals and homosexuality (homophobia). Although a great deal of research has focused on the profile of homophobic individuals, this research provides little theoretical insight into the aetiology of homophobia.

  20. Genetic and environmental influences on individual differences in attitudes toward homosexuality: An Australian twin study

    NARCIS (Netherlands)

    Verweij, K.J.H.; Shekar, S.N.; Zietsch, B.P.; Eaves, L.J.; Bailey, J.M.; Boomsma, D.I.; Martin, N.G.

    2008-01-01

    Previous research has shown that many heterosexuals hold negative attitudes toward homosexuals and homosexuality (homophobia). Although a great deal of research has focused on the profile of homophobic individuals, this research provides little theoretical insight into the aetiology of homophobia.

  1. Tolerance as a Correlate of Experience With Stigma: The Case of the Homosexual

    Science.gov (United States)

    Corbett, Sherry L.; And Others

    1977-01-01

    Scales measuring attitudes toward various unconventional groups were presented to 100 college students and 51 homosexual respondents. Homosexual respondents expressed significantly more tolerant attitudes toward deviantly labeling groups than did student respondents. (Author)

  2. [A model list of high risk drugs].

    Science.gov (United States)

    Cotrina Luque, J; Guerrero Aznar, M D; Alvarez del Vayo Benito, C; Jimenez Mesa, E; Guzman Laura, K P; Fernández Fernández, L

    2013-12-01

    «High-risk drugs» are those that have a very high «risk» of causing death or serious injury if an error occurs during its use. The Institute for Safe Medication Practices (ISMP) has prepared a high-risk drugs list applicable to the general population (with no differences between the pediatric and adult population). Thus, there is a lack of information for the pediatric population. The main objective of this work is to develop a high-risk drug list adapted to the neonatal or pediatric population as a reference model for the pediatric hospital health workforce. We made a literature search in May 2012 to identify any published lists or references in relation to pediatric and/or neonatal high-risk drugs. A total of 15 studies were found, from which 9 were selected. A model list was developed mainly based on the ISMP one, adding strongly perceived pediatric risk drugs and removing those where the pediatric use was anecdotal. There is no published list that suits pediatric risk management. The list of pediatric and neonatal high-risk drugs presented here could be a «reference list of high-risk drugs » for pediatric hospitals. Using this list and training will help to prevent medication errors in each drug supply chain (prescribing, transcribing, dispensing and administration). Copyright © 2013 Asociación Española de Pediatría. Published by Elsevier Espana. All rights reserved.

  3. Psychoanalysis and homosexuality: do we need a new theory?

    Science.gov (United States)

    Auchincloss, E L; Vaughan, S C

    2001-01-01

    No need exists, it is argued, for a new psychoanalytic theory of homosexuality. Certainly psychoanalysis should not be expected to generate such a theory using its own methodology alone. The preoccupation with producing such a theory avoids more important questions about psychoanalytic theory building raised by an examination of the long relationship between psychoanalysis and homosexuality. These questions concern the problems related to using psychoanalytic methodology (1) to construct categories (including the categories normal and abnormal), (2) to construct causal theory (the problems include the limitations of psychoanalytic developmental theory and a long-standing confusion between psychoanalytic developmental theory, psychoanalytic genetic reconstruction, and psychodynamics), and (3) to identify "bedrock." Finally, the question is addressed of what might be needed that is new in the psychoanalytic approach to homosexuality.

  4. Attitudes Toward Homosexuality in Adolescence: An Italian Study.

    Science.gov (United States)

    Santona, Alessandra; Tognasso, Giacomo

    2018-01-01

    This study investigates Italian adolescents' attitudes toward gay men and lesbians and same-sex marriage, and their beliefs about the origins of homosexuality. The sample consists of 449 subjects (226 males), aged between 14 and 21 years. The principal instruments used are: the Attitudes Toward Lesbians and Gay men (ATLG), the Modern Homonegativity Scale (MHS), and the Attitudes Toward Same-Sex Marriage (ATSM). Results suggest that males show a more negative attitude than females toward homosexuals. Furthermore data reveal that respondents with a lack of personal direct contact with gay people have less positive attitudes toward homosexual people and same-sex marriage. The data in this study suggest that homophobia could be deeply rooted in a traditional value system that refutes gender equality.

  5. Essentialism, social constructionism, and the history of homosexuality.

    Science.gov (United States)

    Halwani, R

    1998-01-01

    Social constructionism is the view that homosexuality is not an atemporal and acultural phenomenon. Rather, homosexuality exists only within certain cultures and within certain time periods, most obviously Europe and North America after the nineteenth century. Essentialism is the view that homosexuality is an essential feature of human beings and that it could be found, in principle at least, in any culture and in any time. In this paper, I argue that the historical evidence available to us does not show that social constructionism is the correct view, and that essentialism is fully compatible with such evidence. Furthermore, I argue that the historical evidence does not even render social constructionism more probable than essentialism, i.e., both views are equally probable in the face of this evidence.

  6. Grappling with the issue of homosexuality: perceptions, attitudes, and beliefs among high school students in Kenya

    Science.gov (United States)

    Mucherah, Winnie; Owino, Elizabeth; McCoy, Kaleigh

    2016-01-01

    While the past decade has seen an improvement in attitudes toward homosexuality, negative attitudes are still prevalent in many parts of the world. In general, increased levels of education tend to be predictive of relatively positive attitudes toward homosexuality. However, in most sub-Saharan countries, it is still believed that people are born heterosexual and that nonheterosexuals are social deviants who should be prosecuted. One such country is Kenya, where homosexuality is illegal and attracts a fine or jail term. The purpose of this study was to examine high school students’ perceptions of homosexuality in Kenya. The participants included 1,250 high school students who completed a questionnaire on perceptions of homosexuality. The results showed that 41% claimed homosexuality is practiced in schools and 61% believed homosexuality is practiced mostly in single-sex boarding schools. Consistently, 52% believed sexual starvation to be the main cause of homosexuality. Also, 95% believed homosexuality is abnormal, 60% believed students who engage in homosexuality will not change to heterosexuality after school, 64% believed prayers can stop homosexuality, and 86% believed counseling can change students’ sexual orientation. The consequences for homosexuality included punishment (66%), suspension from school (61%), and expulsion from school (49%). Significant gender and grade differences were found. The implications of the study findings are discussed. PMID:27672345

  7. Differences in Psychological Sex, Adjustment, and Familial Influences Among Homosexual and Nonhomosexual Populations

    Science.gov (United States)

    Townes, Brenda D.; And Others

    1976-01-01

    This study investigates differences in psychological sex, present and past adjustment, and parental influences among homosexual cross-dressers, homosexual non-cross-dressers, applicants for sex change surgery, and heterosexuals. Homosexual non-cross-dressers and heterosexual groups had the most masculine gender role, with the sex change group…

  8. A STUDY ON CLINICAL PROFILE OF SERONEGATIVE SPONDYLOARTHROPATHY IN NORTH KERALA

    Directory of Open Access Journals (Sweden)

    Vijith Kumar Kuttat

    2016-08-01

    Full Text Available INTRODUCTION Seronegative spondyloarthropathy is a group of chronic autoimmune disorders that share common clinical, radiological and genetic features that are clearly distinct from other inflammatory rheumatic diseases and characterised by absence of rheumatoid factor. It includes ankylosing spondylitis, reactive arthritis, psoriatic arthritis, inflammatory bowel disease, acute anterior uveitis, undifferentiated spondyloarthropathies and juvenile spondyloarthropathies. OBJECTIVES To study the clinical profile of adult patients with seronegative spondyloarthropathy and to classify the patients into specific subtypes based on standard clinical criteria. METHODOLOGY A cross-sectional study was conducted among 100 patients with seronegative spondyloarthropathy attending Internal Medicine Department of Calicut Medical College, Kerala using semi-structured questionnaire and standard clinical tests. RESULTS Males were found to be more affected with a male female ratio of 2.7:1. Undifferentiated spondyloarthropathy was the most common subtype followed by Psoriatic arthritis and reactive arthritis. Enthesopathy was noted in 88% of patients. Skin and mucosal involvement was seen in 33%. Morning stiffness and peripheral joint involvement was present in most of the cases. Symmetric polyarthritis was the most common presentation of psoriatic arthritis, seen in the study group. CONCLUSION Prevalence of Seronegative spondyloarthropathies is on the rise among people of North Kerala. Early diagnosis and appropriate treatment is necessary to prevent complications and improve the quality of life of affected persons.

  9. Comparative analysis of seronegative and seropositive rheumatoid arthritis regarding some epidemiological and anamnestic characteristics.

    Science.gov (United States)

    Sahatçiu-Meka, Vjollca; Izairi, Remzi; Rexhepi, Sylejman; Manxhuka-Kerliu, Suzana

    2007-01-01

    Classifying patients into two subsets of the disease--seronegative RA and seropositive RA--has been the subject of many studies which aim to clarify this phenomenon--without any conclusive or acceptable answer so far. The aim of this prospective study was to establish a scientific comparative analysis between seronegative and seropositive rheumatoid arthritis (RA) regarding some epidemiological and anamnestic characteristics. The studied group consisted of seronegative patients with titers lower than 1:64 as defined by Rose-Waaler test, while the control group consisted of seropositive patients with titers of 1:64 or higher. All patients belonged to 2nd and 3rd functional class according to the ARA criteria, were between 25-60 years of age (Xb=49.96), with disease duration between 1-27 years (Xb=6.41). Education, residence, economic and living conditions did not show any significant statistical difference regarding serostatus. Familial clustering of RA confirmed higher susceptibility in the seropositive group (chi2=7.02; p<0.01). In both subsets banal diseases, psychic and physical trauma, weakness, and numbness of hands and legs dominated, without any statistical differenceregarding serostatus. Some differences between groups regarding sex were noticed, but were not statistically significant, except regarding physical trauma, which was more present in seronegative females (chi2=8.05; p<0.01).

  10. Staphylococcus aureus nasal colonization in HIV-seropositive and HIV-seronegative drug users

    NARCIS (Netherlands)

    K.A. Holbrook; R.S. Klein; D. Hartel; D.A. Elliott; T. B. Barsky; L. H. Rothschild; F. D. Lowy

    1997-01-01

    textabstractNasal colonization plays an important role in the pathogenesis of Staphylococcus aureus infections. To identify characteristics associated with colonization, we studied a cross-section of a well-described cohort of HIV-seropositive and -seronegative active and former drug users

  11. Openings: On the Journal of Homosexuality, Volume 1, Issue 1.

    Science.gov (United States)

    Gotkin, Kevin

    2016-01-01

    This article serves as one of the supplementary pieces of this special issue on "Mapping Queer Bioethics," in which we take a solipsistic turn to "map" the Journal of Homosexuality itself. Here, the author examines Volume 1, Issue 1 of the Journal of Homosexuality and asks whether the journal's first contributors might reveal a historically problematic relationship whereby the categories of front-line LGBT health advocates in the 1970s might be incommensurate with the post-AIDS, queer politics that would follow in decades to come.

  12. Marriage and the homosexual body: it's about race.

    Science.gov (United States)

    Keenan, Deirdre

    2012-01-01

    Any analogy between race and homosexuality cannot erase the fact that skin color has marked and continues to mark bodies for special punishment and necessary protection. Yet, the analogy has also been forged in the struggles against sexual discrimination and in the courts to recognize same-sex marriage as a basic civil right. My purposes here are, first, to review the role the race-sexual orientation analogy has played in same-sex marriage debates, second to examine the analogy within the context of race and queer theories and, finally, to suggest a racial dimension to sexuality that marks the homosexual body.

  13. Heterosexual sexual behaviour in a sample of homosexually active men.

    OpenAIRE

    Fitzpatrick, R; Hart, G; Boulton, M; McLean, J; Dawson, J

    1989-01-01

    Three hundred and fifty six homosexually active men were recruited in 1988 for a study by interview of sexual behaviour. Thirty two per cent had homosexual passive anal sex in the previous month and 60% in the year before interview. Anal sex and unprotected anal sex were more common with regular than non-regular partners. Heterosexual sex was reported by 4% of men in the last month and 10% for the last year. Sixteen per cent of heterosexually active men reported anal sex with a female partner...

  14. Floating call boys and agile homosexuals: homophobia/Venice/history.

    Science.gov (United States)

    Champagne, John

    2014-01-01

    Because works of nonfiction are always composed of literary tropes and metaphors, they have to be read critically for the ways in which their truth claims are potentially structured by ideologies and stereotypes. This essay reads passages from Richard Sennett's sociological analysis Flesh and Stone, The Body and the City in Western Civilization and Joseph Brodsky's memoir Watermark in order to demonstrate how these alleged works of nonfiction shore up some dishearteningly familiar literary stereotypes of male homosexuality and participate in a tradition, dating from the 19th century, of linking the city of Venice with homosexuality and death.

  15. Long-term MRI findings in neuromyelitis optica: seropositive versus seronegative patients.

    Science.gov (United States)

    Kıyat-Atamer, A; Ekizoğlu, E; Tüzün, E; Kürtüncü, M; Shugaiv, E; Akman-Demir, G; Eraksoy, M

    2013-05-01

    Neuromyelitis optica (NMO) is a severe demyelinating inflammatory disorder associated with serum antibodies against aquaporin 4 (AQP4-Ab). A significant number of patients with NMO remain seronegative over time. Long-term observational magnetic resonance imaging (MRI) studies of the CNS in patients with NMO are rare or of limited duration. The objective of this study is to determine long-term MRI characteristics of seropositive and seronegative patients, and assess possible overlap with multiple sclerosis (MS). Clinical and radiological characteristics of 28 patients with NMO at onset and of 17 patients after an average follow-up time of 9 years were recorded. Fifty percent of patients were seropositive for AQP4-Ab. Onset and final brain/spinal MRI scans were retrospectively analysed and compared. Significantly more patients in the seronegative group had brain lesions at onset. Spinal lesions of seropositive patients were longer and showed increased cord swelling at onset MRI scans. After the follow-up time the differences between both groups disappeared. Patients in the seropositive group tended to develop brain lesions over time. No patient fulfilled Barkhof's or McDonald's radiological criteria for MS at onset or over time. Brain MRI features show differences between seropositive and seronegative patients at time of onset in NMO, but differences between groups vanish over time. None of the AQP4-negative patients fulfill radiological MS criteria on a long-term basis, suggesting that seronegative NMO constitutes an independent entity. © 2012 The Author(s) European Journal of Neurology © 2012 EFNS.

  16. Cultural change, hybridity and male homosexuality in Mexico.

    Science.gov (United States)

    Carrillo, H

    1999-01-01

    This paper analyzes how contemporary perceptions of male homosexuality are being shaped in Mexico. Ethnographic analysis included four short case studies from 64 mostly middle class individuals for two years in Guadalajara City. Mexican sexual culture is often portrayed traditionally as grounded in values inherent in machismo and influenced by Catholicism. There is a contrast between these traditional interpretations of roles and sexual identities in Mexico and the identities that are being adopted by many contemporary Mexican homosexual men. The homosexual men were categorizable in terms of 1) those who dominated in the sexual relationship and who were capable of maintaining a nonstigmatized identity as regular men, 2) those who assumed a feminine role and were penetrated and who were stigmatized for their effeminate demeanor, and 3) a minority of men who assumed both roles and who were termed "anally active and passive". The study revealed that middle-class homosexuals established networks in which individuals, supported by their friends, acquired the strength to effect personal changes along with other larger cultural changes. Thus, individual actions are beginning to have a collective effect on the society at large.

  17. Teaching Literature Gay-Affirmatively: A Homosexual Individuation Story

    Science.gov (United States)

    Sadownick, Douglas G.

    2007-01-01

    This article explores the possibility of a "homosexual hermeneutic" by which the great literary works of the western canon can be taught. This "interpretative methodology" is based in the author's own individuation process as gay. The author details his personal journey from engulfment in heteronormativity to the first crisis of his homosexual…

  18. Should We Teach Homosexuality as a Controversial Issue?

    Science.gov (United States)

    Hand, Michael

    2007-01-01

    Philosophers of education disagree on how the question of the moral status of homosexual acts should be tackled in the classroom. Some argue that the question should be taught as a controversial issue, that we should present rival moral positions as even-handedly as possible; others maintain that we should actively promote the view that homosexual…

  19. Attitudes toward Homosexuals among Students at a Canadian University.

    Science.gov (United States)

    Schellenberg, E. Glenn; Hirt, Jessie; Sears, Alan

    1999-01-01

    Examined attitudes toward homosexuals among 199 male and female students at a Canadian university. Attitudes toward gay men were more negative than attitudes toward lesbians. For male students, attitudes toward gay men improved with time spent at college, suggesting the influence of college in reducing antihomosexual prejudice. (SLD)

  20. Prenatal Estrogens and the Development of Homosexual Orientation.

    Science.gov (United States)

    Meyer-Bahlburg, Heino F. L.; And Others

    1995-01-01

    Examines the hypothesis that prenatal estrogens contribute to the development of human sexual orientation. Several groups of women with a history of prenatal exposure to diethylstilbestrol (DES) were compared with several samples of control women. Findings showed that more DES-exposed women than controls were rated as bisexual or homosexual,…

  1. Queer Breeding: Historicising Popular Culture, Homosexuality and Informal Sex Education

    Science.gov (United States)

    Marshall, Daniel

    2013-01-01

    Through an analysis of gay protest music (1975) and an educational kit for students (1978), both sponsored by the Campaign for Homosexual Equality in the UK, this paper brings into focus a history of gay rights activists' efforts to marshal popular culture in the development of informal sex education for young people in the second half of the…

  2. Correlates of health attitudes among homosexual and bisexual men

    Directory of Open Access Journals (Sweden)

    Deborah A. Gust

    2013-03-01

    Full Text Available There is increased emphasis on physician attention to the overall health and wellness of homosexual and bisexual men, though little is known about the health-related attitudes of these groups. This study determined factors associated with the health attitudes of homosexual and bisexual men and identified preferred sources of health information. For this study, the 2008 ConsumerStyles panel survey was used to create three health attitude scales and to determine factors associated with each scale. The three scales were labeled: (1 health motivation; (2 relationship with health care provider; and (3 self-perception of health literacy. In addition to other factors, higher scores for health motivation and relationship with health care provider were associated with black compared with white men. In contrast, lower scores for self-perception of health literacy were associated with black compared with white men. For information on an unfamiliar health condition, most homosexual and bisexual men chose the Internet. Black homosexual and bisexual men reported being motivated to be healthy and working well with their health care provider to manage their health. However, their perception of their own health motivation was low compared with the white men. Attempts to improve health literacy through Internet sites may be helpful in improving health attitudes and reducing negative health outcomes.

  3. Excess of counterclockwise scalp hair-whorl rotation in homosexual

    Indian Academy of Sciences (India)

    While most men prefer women as their sexual partners, some are bisexual and others are homosexuals. It has been debated for a long time whether a person's sexual preference is innate, learned, or due to a combination of both causes. It was recently discovered that the human right-versus-left-hand use preference and ...

  4. The interrelationship between genes, microprolactinoma and male homosexuality.

    Science.gov (United States)

    Roper, Walter Geoffrey

    2016-09-01

    This hypothesis clearly proposes the true and previously undiscovered cause of male homosexuality or bisexuality and in most cases the predictability in infancy of the development of this sexuality in adulthood. It is based on compelling new evidence which has accumulated over many years. The fetal and neonatal periods are of the utmost importance in human development because they encompass critical periods which must be adhered to, for normal development. Biological variations may occur during these times, without implying the process of disease. This paper takes into account new paediatric hormonal and other evidence which has accumulated in the past two decades concerning the causation of male homosexuality or bisexuality. It includes indirect genetic influence which has now been shown to be present. It also includes the implications of infant male breast development in regard to sexuality. It is asserted that the major cause of male homosexuality is due to failure of masculinisation of the male brain due to temporary but critical prolactin secretion from microprolactinoma present in their pituitary glands. Genes appear to be involved in the production of these tumours and sometimes in their demise. The assessment of their numbers at any one time in infancy has not been correctly addressed. Secondly, there is absolutely compulsive evidence concerning increased male infant breast development and the true nature of "Witch's Milk" and how it is produced and the profound implications of its presence in male neonates. It adds much persuasion to the causation of male homosexuality as enunciated in this paper. Measurement of testosterone levels at exactly and precisely the right time, are able to predict homosexual or bisexual development in adults. This knowledge would be of great help to parents. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. Cultural factors affecting urban Mexican male homosexual behavior.

    Science.gov (United States)

    Carrier, J M

    1976-03-01

    Some aspects of the mestizoized urban culture in Mexico are linked to male homosexuality in support of the theory that cultural factors play an important role in the kind of life styles and sex practices of males involved in homosexual behavior. The following factors are considered relevant: the sharp dichotomization of gender roles, dual categorization of females as good or bad, separate social networks maintained by males before and after marriage, proportion of unmarried males, and distribution of income. One result of the sharp dichotomization of male and female gender roles is the widely held belief that effeminate males generally prefer to play the female role rather than the male. Effeminacy and homosexuality are also linked by the belief that as a result of this role preference effeminate males are sexually interested only in masculine males with whom they play the passive sex role. The participation of masculine males in homosexual encounters is related in part to a relatively high level of sexual awareness in combination with the lack of stigmatization of the insertor sex role and in part to the restraints placed on alternative sexual outlets by available income and/or marital status. Males involved in homosexual behavior in Mexico operate in a sociocultural environment which gives rise to expectations that they should play either the insertee or insertor sex role but not both and that they should obtain ultimate sexual satisfaction with anal intercourse rather than fellatio. In spite of cultural imperatives, however, individual preferences stemming from other variables such as personality needs, sexual gratification, desires of wanted partners, and amount of involvement may override the imperatives with resulting variations in sexual behavior patterns.

  6. Unilateral RS3PE in a Patient of Seronegative Rheumatoid Arthritis

    Directory of Open Access Journals (Sweden)

    Ankur Nandan Varshney

    2013-01-01

    Full Text Available Remitting seronegative symmetrical synovitis with pitting edema (RS3PE is a rare but well-reported clinical entity. It is classically described as symmetrical involvement of both upper extremities. Asymmetrical involvement had also been reported, but unilateral presentation is very rare. We hereby report a case of unilateral RS3PE in a patient of seronegative rheumatoid arthritis which was initially misdiagnosed as cellulitis and was given high dose antibiotics without any significant improvement. Later a rheumatologic consultation leads to a prompt diagnosis, and treatment with steroids leads to dramatic reversal of symptoms. This case demonstrates the rare presentation of this rare clinical entity and highlights the necessity of awareness regarding unilateral disease to clinicians.

  7. Assessment of local carotid stiffness in seronegative and seropositive rheumatoid arthritis.

    Science.gov (United States)

    Aslan, Abdullah Nabi; Şirin Özcan, Ayşe Nur; Erten, Şükran; Alsancak, Yakup; Durmaz, Tahir

    2017-10-01

    Rheumatoid arthritis (RA) is a chronic, inflammatory disease associated with increased risk of cardiovascular (CV) disease. Arterial stiffness (AS) is an independent predictor of CV events. This study aimed to analyse local carotid AS parameters in seronegative and seropositive RA patients. Of 347 consecutive RA patients, we selected specifically those who were free of established CV diseases and risk factors. As a result, 140 patients (126 women, 52.2 ± 10 years) and 140 healthy controls (122 women, 52.7 ± 8.0 years) were enrolled into this study. The common carotid AS was evaluated using radio frequency echo-tracking system to determine the local carotid pulse wave velocity (cPWV) and carotid intima-media thickness (cIMT). Based on rheumatoid factor (RF) and/or anti-citrullinated protein antibody (ACPA) positivity, RA patients were categorized into seronegative and seropositive subgroups. Carotid PWV was determined to be significantly higher in all patients and subgroups than controls (p < .001 for all). Although cIMT was similar between the patients, controls and seropositive subgroup, seronegative patients had significantly higher cIMT compared to controls (p = .035) and seropositive group (p = .010). Moreover, a significant positive correlation was found between cPWV and age (r: 0.603, p < .001), ESR (r: 0.297, p = .004), ACPA (r: 0.346, p = .001) and cIMT (r: 0.290, p = .005) in seropositive patients. RA per se is sufficient to cause arteriosclerosis in the absence of classical CV risk factors. However, arterial hypertrophy is only increased in seronegative patients but not in seropositive group.

  8. Learners’ perceptions of learners regarded as having a homosexual orientation in an independent secondary school environment

    Directory of Open Access Journals (Sweden)

    Hendrik P. Mostert

    2012-10-01

    Full Text Available In schools today discrimination based on sexual orientation takes place on a regular basis. This form of discrimination leads to aggression towards learners perceived to be homosexual, as well as towards those with a homosexual orientation. For more than 15 years South Africa has been a democratic country with laws that protect learners who have a homosexual orientation. Nevertheless, aggression and discrimination towards these learners still occur in schools. Aggression often leads to verbal and physical bullying of the victims by perpetrators. The objectives of this research were to explore and describe Grade 11 learners’ experiences of aggression towards learners perceived to be homosexual as well as those with a homosexual orientation in an independent secondary school environment. The research design was qualitative, exploratory, descriptive and contextual in nature. The data for this investigation consisted of essays based on a published newspaper photograph, phenomenological group interviews, observations and field notes. Tesch’s method of data analysis was used, and an independent coder assisted. Three themes were identified, discussed and supported by a literature control: that learners experience that it is right and acceptable to have a homosexual orientation; that they experience ambivalence towards homosexual orientation of learners; and experienced feelings that it is wrong to have a homosexual orientation. Recommended guidelines are provided to address aggression towards learners perceived to be homosexual and those with a homosexual orientation.

  9. Learners' perceptions of learners regarded as having a homosexual orientation in an independent secondary school environment.

    Science.gov (United States)

    Mostert, Hendrik P; Myburgh, Chris; Poggenpoel, Marie

    2012-10-04

    In schools today discrimination based on sexual orientation takes place on a regular basis. This form of discrimination leads to aggression towards learners perceived to be homosexual, as well as towards those with a homosexual orientation. For more than 15 years South Africa has been a democratic country with laws that protect learners who have a homosexual orientation. Nevertheless, aggression and discrimination towards these learners still occur in schools. Aggression often leads to verbal and physical bullying of the victims by perpetrators. The objectives of this research were to explore and describe Grade 11 learners' experiences of aggression towards learners perceived to be homosexual as well as those with a homosexual orientation in an independent secondary school environment. The research design was qualitative, exploratory, descriptive and contextual in nature. The data for this investigation consisted of essays based on a published newspaper photograph, phenomenological group interviews, observations and field notes. Tesch's method of data analysis was used, and an independent coder assisted. Three themes were identified, discussed and supported by a literature control: that learners experience that it is right and acceptable to have a homosexual orientation; that they experience ambivalence towards homosexual orientation of learners; and experienced feelings that it is wrong to have a homosexual orientation. Recommended guidelines are provided to address aggression towards learners perceived to be homosexual and those with a homosexual orientation.

  10. Evaluation of 278 hla-b27 positive patients suspected of seronegative spondyloarthropathies

    International Nuclear Information System (INIS)

    Eman, S.J.; Badri, S.; Khosravi, A.

    2007-01-01

    To determine HLA-B27 prevalence in patients suspected of Seronegative spondyloarthropathy referred to the Transplantation Department of Blood Transfusion Organization, and to evaluate clinical findings among HLA-B27 positive patients. One thousand six hundred ten patients having clinical manifestation of seronegative SpAs were screened for HLA typing by serological methods from January 1997 to June 2002 at Transplantation Department of Blood Transfusion Organization, Ahwaz, Iran. Serologic-based HLA typing using Antigen-specific sera to determine a person's HLA type was performed. Among these patients, individuals found HLA-B27 positive were investigated regarding clinical findings, age, and sex distribution. In this study the frequency of HLA-B27 antigen was 17.26% (278 cases). The minimum age in males was 10 years and the maximum age in female was 70 years. Median age with seronegative SpAs findings (34.2% including 28.42% females, 71.57% males) was 20-30 years. Based on our results, the most frequent clinical manifestation, was peripheral joints arthritis (58.7%; 34.35% females, 65.65 % males). There were no association between any of the major clinical manifestations and age or sex distribution. These findings confirm the strong association of the HLA B27 allele with various types of spondyloarthritis and suggests that HLA typing would help in the diagnosis of seronagative SpAs, specially ankylosing spondylitis with indeterminate clinical presentation and also in identifying at risk family members. (author)

  11. Characterization of rubella seronegative females in the Zambian blood donor community

    Directory of Open Access Journals (Sweden)

    Mazyanga Lucy Mazaba

    2015-04-01

    Full Text Available Rubella is an acute, contagious viral infection caused by a teratogenic enveloped single-stranded RNA virus, rubella virus, a member of the togaviridae family. Though causing generally mild infections in children and adults, it is a disease of public health importance in pregnant women causing major problems including abortions, miscarriages and Congenital Rubella Syndrome in more than twenty per cent of the susceptible population. This study was carried out to determine the characteristics associated with rubella seronegativity amongst female blood donors in Zambia. Rubella-specific IgG antibody levels were measured in the blood serum. Proportions were compared using the Chi-squared test at the 5% significance level, and magnitudes of associations were determined using the odds ratio and its 95% confidence interval. Of the 124 female blood donors tested for rubella IgG 46.0% were aged less than 20 years. Overall, 66.7% of the participants had never been married. More than half (62.1% of the participants resided in rural areas of the country. Of the 114 participants with recorded level of education, 50.1% had at–least completed secondary school. Out of 43 participants with recorded current employment status, 44.2% were not working for pay. A total of 10 (8.1% participants were sero-negative to rubella IgG antibodies. No factors were associated with seronegativity. Protection against rubella through natural infection appears inadequate to protect the population, increasing the risk of CRS.

  12. Grappling with the issue of homosexuality: perceptions, attitudes, and beliefs among high school students in Kenya

    Directory of Open Access Journals (Sweden)

    Mucherah W

    2016-09-01

    Full Text Available Winnie Mucherah,1 Elizabeth Owino,2 Kaleigh McCoy,1 1Department of Educational Psychology, Ball State University, Muncie, IN, USA, 2Department of Educational Psychology, Moi University, Eldoret, Kenya Abstract: While the past decade has seen an improvement in attitudes toward homosexuality, negative attitudes are still prevalent in many parts of the world. In general, increased levels of education tend to be predictive of relatively positive attitudes toward homosexuality. However, in most sub-Saharan countries, it is still believed that people are born heterosexual and that nonheterosexuals are social deviants who should be prosecuted. One such country is Kenya, where homosexuality is illegal and attracts a fine or jail term. The purpose of this study was to examine high school students’ perceptions of homosexuality in Kenya. The participants included 1,250 high school students who completed a questionnaire on perceptions of homosexuality. The results showed that 41% claimed homosexuality is practiced in schools and 61% believed homosexuality is practiced mostly in single-sex boarding schools. Consistently, 52% believed sexual starvation to be the main cause of homosexuality. Also, 95% believed homosexuality is abnormal, 60% believed students who engage in homosexuality will not change to heterosexuality after school, 64% believed prayers can stop homosexuality, and 86% believed counseling can change students’ sexual orientation. The consequences for homosexuality included punishment (66%, suspension from school (61%, and expulsion from school (49%. Significant gender and grade differences were found. The implications of the study findings are discussed. Keywords: homosexuality, attitudes, beliefs, high school, Kenya

  13. Homosexuality among People with a Mild Intellectual Disability: An Explorative Study on the Lived Experiences of Homosexual People in the Netherlands with a Mild Intellectual Disability

    Science.gov (United States)

    Stoffelen, J.; Kok, G.; Hospers, H.; Curfs, L. M. G.

    2013-01-01

    Background: Empirical research on homosexuality among people with an intellectual disability (ID) is limited and, to date, very little is known regarding the personal experiences of gay and lesbian people with an ID. This study set out to answer the question: "What are the lived experiences of a specific cohort of homosexual people with an…

  14. High-Risk Series: An Update

    Science.gov (United States)

    2015-02-01

    the Medicare Trustees, the Office of the Actuary , and the Congressional Budget Office have raised concerns about whether some of the Medicare... actuarially sound. For more information, see the National Flood Insurance Program section of this High-Risk report. Among other things, the report...and mathematics (STEM) functional community. In addition to the efforts of the Working Group, the President’s Fiscal Year 2013 budget—released in

  15. Sex differences in the events that elicit jealousy among homosexuals

    OpenAIRE

    Dijkstra, Pieternel; Groothof, Hinke A. K.; Poel, Gerda A.; Laverman, Teunis, T. G.; Schrier, Michiel; Buunk, Bram P.

    2008-01-01

    When individuals are asked which event would upset them more - a partner's emotional infidelity or a partner's sexual infidelity- among heterosexuals more men than women select a partner's sexual infidelity as the most upsetting event, whereas more more women than men select a partner's emotional infidelity as the most upsetting event. Because homosexuals' mating psychology is unlike that of heterosexuals, the present study examinend which of these two events is more upsetting in a sample of ...

  16. Internalized homophobia in homosexual men: a qualitative study

    Directory of Open Access Journals (Sweden)

    Adalberto Campo-Arias

    2015-07-01

    Full Text Available There is little evidence about linguistic expressions used that show internalized homophobia by homosexual individuals. The objective of this research was to explore suggestive internalized homophobic language used by web page users for homosocialization purposes among homosexual men living in Bogotá and Cartagena, Colombia. A qualitative study was designed with the purpose of analyzing content of 40 profiles, 20 from Bogota, and in the same proportion in Cartagena. This was based on account profiles from a website which contained contact inquiries between people who were not heterosexual and described homophobic characteristics when referring to their ideal partner. It was observed that in 19 out of 20 profiles in Bogotá and the same proportion in Cartagena people used suggestive and direct qualifiers that showed internalized explicit homophobia and implicit language, for instance, “I am looking for serious people”. The internalized homophobia is expressed by looking for that “macho” man who is professional and lives a heterosexual lifestyle. Authors conclude that homosexual men who requested contact with other men by Internet often expressed internalized homophobia in explicit and implicit ways, which suggests accepting hegemonic model of masculine men. Quantitative studies are needed in Colombian non-heterosexual populations.

  17. Do Schools Discriminate Against Homosexual Parents? Evidence from an Internet Field Experiment

    OpenAIRE

    Diaz-Serrano, Luis; Meix-Llop, Enric

    2015-01-01

    The recognition of homosexual rights is a controversial issue in many countries. Spain was the third country in the world (after Netherlands and Belgium) to introduce a law recognizing homosexual marriage and adoption of children. In this paper, we examine for the first time whether schools are more hesitant to give feedback to homosexual parents during children's pre-registration period in Spain. In order to do that, we designed an internet field experiment to be conducted in ...

  18. The nature of perceived discriminatory experiences of homosexual individuals at work

    OpenAIRE

    2015-01-01

    M.Com. (Industrial Psychology) In line with recent media reports, it is apparent that homosexual individuals are treated unfairly in a variety of contexts. Yet, little is known regarding the discrimination of homosexual employees in the South African workplace. The objective of this study was to examine the nature of discriminatory experiences of South African homosexual employees. In this study a qualitative approach was used with hermeneutic phenomenology as the method of data analysis. ...

  19. Experiences of homosexual patients’ access to primary health care services in Umlazi, KwaZulu-Natal

    OpenAIRE

    Nokulunga H. Cele; Maureen N. Sibiya; Dudu G. Sokhela

    2015-01-01

    Background: Homosexual patients are affected by social factors in their environment, and as a result may not have easy access to existing health care services. Prejudice against homosexuality and homosexual patients remains a barrier to them seeking appropriate healthcare. The concern is that lesbians and gays might delay or avoid seeking health care when they need it because of past discrimination or perceived homophobia within the health care thereby putting their health at risk. Aim of...

  20. High risk process control system assessment methodology

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Venetia [Pontificia Universidade Catolica do Rio de Janeiro (PUC-Rio), RJ (Brazil); Zamberlan, Maria Cristina [National Institute of Tehnology (INT), Rio de Janeiro, RJ (Brazil). Human Reliability and Ergonomics Research Group for the Oil, Gas and Energy Sector

    2009-07-01

    The evolution of ergonomics methodology has become necessary due to the dynamics imposed by the work environment, by the increase of the need of human cooperation and by the high interaction between various sections within a company. In the last 25 years, as of studies made in the high risk process control, we have developed a methodology to evaluate these situations that focus on the assessment of activities and human cooperation, the assessment of context, the assessment of the impact of work of other sectors in the final activity of the operator, as well as the modeling of existing risks. (author)

  1. The high-risk plaque initiative

    DEFF Research Database (Denmark)

    Falk, Erling; Sillesen, Henrik; Muntendam, Pieter

    2011-01-01

    The High-Risk Plaque (HRP) Initiative is a research and development effort to advance the understanding, recognition, and management of asymptomatic individuals at risk for a near-term atherothrombotic event such as myocardial infarction or stroke. Clinical studies using the newest technologies...... have been initiated, including the BioImage Study in which novel approaches are tested in a typical health plan population. Asymptomatic at-risk individuals were enrolled, including a survey-only group (n = 865), a group undergoing traditional risk factor scoring (n = 718), and a group in which all...

  2. Comparison of Face-to-Face and Web Surveys on the Topic of Homosexual Rights.

    Science.gov (United States)

    Liu, Mingnan; Wang, Yichen

    2016-06-01

    Although academic research on homosexuality relies heavily on survey data, there has been limited study of the survey method of asking relevant questions. This study examines the effect of survey mode on responses to questions about homosexual rights. We find significant mode effects among heterosexual respondents, who are more likely to support equal access to employment, military service, adoption, and marriage for homosexual people in face-to-face surveys than in Web surveys. They are also more likely to choose to not respond when face-to-face than online. Homosexual respondents do not show mode effects for either substantive responses or item nonresponse rate.

  3. Laser prostatectomy in high-risk patients

    International Nuclear Information System (INIS)

    Tayib, Abdulmalik M.

    2008-01-01

    Objective was to evaluate the short-term tolerability and outcome of high power green light potassium titanyl phosphate laser prostatectomy in high-risk patients with symptomatic benign prostatic hyperplasia. Eleven high risk operative patients were included in this study at the International Medical Center, Jeddah, Kingdom of Saudi Arabia, between January and September 2007. Patients enrolled in this study underwent preoperative and postoperative, cardiac and anesthesia evaluation. Clinical presentations, ultrasound of urinary tract and preoperative laboratory investigation were recorded. All patients underwent high power green light laser prostatectomy using the green light photo vaporization system with setting of 120 watts. The intraoperative and postoperative complications and follow-up were recorded. The patient's age varied between 65-82 years with a mean age of 75.3+-8.6 years old. Seven patients presented with refractory acute urinary retention and 4 patients presented with severe lower urinary tract symptoms. The average prostate volume was 61.22 cc. All patients had uneventful intra- and postoperative course, without the intensive care. The average blood loss was insignificant and only one of the patients required blood transfusion. Foley catheters were removed one day after the procedure. All patients voided satisfactorily after removal of catheter and 8 patients complained of urgency. High power green light laser prostatectomy is a safe and effective method of treating symptomatic benign prostatic hyperplasia in patients with high operative risk. (author)

  4. New information on high risk breast screening

    International Nuclear Information System (INIS)

    Riedl, C.C.; Ponhold, L.; Gruber, R.; Pinker, K.; Helbich, T.H.

    2010-01-01

    Women with an elevated risk for breast cancer require intensified screening beginning at an early age. Such high risk screening differs considerably from screening in the general population. After an expert has evaluated the exact risk a breast MRI examination should be offered at least once a year and beginning latest at the age of 30 depending on the patients risk category. Complementary mammograms should not be performed before the age of 35. An additional ultrasound examination is no longer recommended. To ensure a high sensitivity and specificity high risk screening should be performed only at a nationally or regionally approved and audited service. Adequate knowledge about the phenotypical characteristics of familial breast cancer is essential. Besides the common malignant phenotypes, benign morphologies (round or oval shape and smooth margins) as well as a low prevalence of calcifications have been described. Using MRI benign contrast media kinetics as well as non-solid lesions with focal, regional and segmental enhancement can often be visualized. (orig.) [de

  5. Vasculitic central retinal vein occlusion: The presenting sign of seronegative rheumatoid arthritis

    Directory of Open Access Journals (Sweden)

    Matthew G.J. Trese

    2016-07-01

    Conclusions and importance: We hypothesize that the systemic inflammation—a hallmark of RA—led to the development of a vasculitic CRVO and, thus, the retinal manifestations served as the disease marker that prompted thorough work-up of the patient's disease, even in the face of initial seronegativity. This case serves as a reminder that, in the setting of CRVO and polyarthralgia, systemic inflammatory conditions must be considered as the underlying etiology. Further, this case report highlights our evolving understanding of the role that serologic markers play in the diagnosis and monitoring of RA.

  6. [Combined application of balneotherapy to the medical rehabilitation of patients with seronegative spondyloarthrites].

    Science.gov (United States)

    Barnatskiĭ, V V

    2008-01-01

    A rehabilitative complex combining radon baths and ultra-high frequency electromagnetic fields exerted a well-apparent beneficial effect on the clinical picture of articular and vertebral syndromes and greatly contributed to the correction of disturbances in the immune system of patients with seronegative spondyloarthritis. At the same time, combination of radon baths with low-frequency ultrasound treatment and hydrocortisone ultraphonophoresis reduced clinical activity of the disease, improved the patients' immune status, and had more prominent general anti-inflammatory action than the same physical factors applied as monotherapy.

  7. Neural activation toward erotic stimuli in homosexual and heterosexual males.

    Science.gov (United States)

    Kagerer, Sabine; Klucken, Tim; Wehrum, Sina; Zimmermann, Mark; Schienle, Anne; Walter, Bertram; Vaitl, Dieter; Stark, Rudolf

    2011-11-01

    Studies investigating sexual arousal exist, yet there are diverging findings on the underlying neural mechanisms with regard to sexual orientation. Moreover, sexual arousal effects have often been confounded with general arousal effects. Hence, it is still unclear which structures underlie the sexual arousal response in homosexual and heterosexual men. Neural activity and subjective responses were investigated in order to disentangle sexual from general arousal. Considering sexual orientation, differential and conjoint neural activations were of interest. The functional magnetic resonance imaging (fMRI) study focused on the neural networks involved in the processing of sexual stimuli in 21 male participants (11 homosexual, 10 heterosexual). Both groups viewed pictures with erotic content as well as aversive and neutral stimuli. The erotic pictures were subdivided into three categories (most sexually arousing, least sexually arousing, and rest) based on the individual subjective ratings of each participant. Blood oxygen level-dependent responses measured by fMRI and subjective ratings. A conjunction analysis revealed conjoint neural activation related to sexual arousal in thalamus, hypothalamus, occipital cortex, and nucleus accumbens. Increased insula, amygdala, and anterior cingulate gyrus activation could be linked to general arousal. Group differences emerged neither when viewing the most sexually arousing pictures compared with highly arousing aversive pictures nor compared with neutral pictures. Results suggest that a widespread neural network is activated by highly sexually arousing visual stimuli. A partly distinct network of structures underlies sexual and general arousal effects. The processing of preferred, highly sexually arousing stimuli recruited similar structures in homosexual and heterosexual males. © 2011 International Society for Sexual Medicine.

  8. Prescription of the High Risk Narcotics and Trading or Illicit Purchasing of High Risk Narcotics

    Directory of Open Access Journals (Sweden)

    Nicoleta-Elena Buzatu

    2012-05-01

    Full Text Available The present essay will analyze the offence of prescribing high risk narcotics and trading or illicit purchasing of high risk narcotics, as it was regulated - together with other offences - by Law no 143 of July 26, 2000 on preventing and fighting against the traffic and illicit consumption of narcotics. The same law defines the meaning of such a phrase “substances which are under national control” by mentioning the fact that they are the narcotics and their precursors listed in Annexes I-IV of the law. The analysis of the offence of prescribing the high risk narcotics and trading or illicit purchasing of high risk narcotics is following the already known structure mentioned in the doctrine and which consists of: object and subjects of the offence, its constituent content: the objective side with its material element, the immediate consequence and causality connections; the subjective side of the offence, as well as forms and modalities of these offences, and the applicable sanctions, of course.

  9. Effects of Attractiveness and Status in Dating Desire in Homosexual and Heterosexual Men and Women

    NARCIS (Netherlands)

    Ha, P.T.; Berg, J.E.M. van den; Engels, R.C.M.E.; Lichtwarck-Aschoff, A.

    2012-01-01

    The present study examined partner preferences of homosexual and heterosexual men and woman, focusing on attractiveness and status. Homosexual (N = 591 men; M age = 28.87 years, SD = 10.21; N = 249 women; M age = 33.36 years, SD = 13.12) and heterosexual participants (N = 346 men; M age = 39.74

  10. The Relationship between Gender and Heterosexual Attitudes toward Homosexuality at a Conservative Christian University

    Science.gov (United States)

    LaFave, Adam D.; Helm, Herbert W., Jr.; Gomez, Omar

    2014-01-01

    This research looked at the relationships and differences between sex and race as it relates to religious fundamentalism, attitudes, and comfortability toward homosexuality. Patterns in previous research have shown that men and women do differ in their attitudes toward homosexuals. This study proposed that heterosexual men will show a…

  11. Homosexual orientation-from nature, not abuse: A critique of Roberts, Glymour, and Koenen (2013).

    Science.gov (United States)

    Rind, Bruce

    2013-11-01

    Roberts, Glymour, and Koenen (2013), using instrumental variable models, argued that child abuse causes homosexual orientation, defined in part as any same-sex attractions. Their instruments were various negative family environment factors. In their analyses, they found that child sexual abuse (CSA) was more strongly related to homosexual orientation than non-sexual maltreatment was, especially among males. The present commentary therefore focused on male CSA. It is argued that Roberts et al.'s "abuse model" is incorrect and an alternative is presented. Male homosexual behavior is common in primates and has been common in many human societies, such that an evolved human male homosexual potential, with individual variation, can be assumed. Cultural variation has been strongly influenced by cultural norms. In our society, homosexual expression is rare because it is counternormative. The "counternormativity model" offered here holds that negative family environment weakens normative controls and increases counternormative thinking and behavior, which, in combination with sufficient homosexual potential and relevant, reinforcing experiences, can produce a homosexual orientation. This is a benign or positive model (innate potential plus release and reinforcement), in contrast to Roberts et al.'s negative model (abuse plus emotional compensation or cognitive distortion). The abuse model is criticized for being based on the sexual victimological paradigm, which developed to describe the female experience in rape and incest. This poorly fits the gay male experience, as demonstrated in a brief non-clinical literature review. Validly understanding male homosexuality, it is argued, requires the broad perspective, as employed here.

  12. Suicide and Homosexual Teens: What Can Biology Teachers Do to Help?

    Science.gov (United States)

    Smith, Mike U.; Drake, Mary Ann

    2001-01-01

    Discusses the teacher's role in helping students deal with homosexuality and suicide. Teachers can provide unbiased information about personal relevant biological issues; be good listeners and confidantes; and value each student without regard to race, gender, class, or sexual orientation. Provides useful information on addressing homosexuality in…

  13. Promoting Communication: Teaching Tolerance of Homosexual Persons While Addressing Religious Fears.

    Science.gov (United States)

    Levesque, PJ

    This paper addresses how to teach tolerance of homosexual persons in a manner that is not threatening to those with religious scruples about homosexuals. It contains an example of a presentation for college students that is designed to teach them to respect their peers and future coworkers regardless of their sexual orientation. The presentation…

  14. Teaching about Homosexualities to Nigerian University Students: A Report from the Field

    Science.gov (United States)

    Epprecht, Marc; Egya, Sule E.

    2011-01-01

    Nigeria's diverse cultures, religions and political parties appear to be unified by a strong taboo against homosexuality and gay rights. This has affected academic research, HIV/AIDS programmes, and sexuality education, all which commonly show evidence of heterosexism, self-censorship and even explicit condemnations of homosexuality. Yet a…

  15. Birth Order and Sibling Sex Ratio in Homosexual Male Adolescents and Probably Prehomosexual Feminine Boys.

    Science.gov (United States)

    Blanchard, Ray; And Others

    1995-01-01

    Examined the hypothesis that male homosexuals have a greater than average proportion of male siblings and a later than average birth order, by comparing a group of prehomosexual boys (individuals exhibiting cross-gender behaviors) and homosexual adolescents with a control group. Both predicted results were confirmed. (MDM)

  16. WORKING WITH HOMOSEXUAL CLIENTS: Application of Solution-Focused Therapy

    Directory of Open Access Journals (Sweden)

    Husmiati Husmiati

    2012-04-01

    Full Text Available This article discusses the psychosocial problems dealt by gay, lesbian, and bisexual clients. Gay is an individual who has sex orientation to male, whereas lesbian is to female. Bisexual has both sex orientation towards male and female. This article also points out one approach called Solution-Focused Therapy (SFT which can be applied in clinical practice. Working with SFT technique to homoerotic individual or group is significantly different to common people. Mental health experts such as social workers and clinical psychologists should have this understanding. Keywords: Homosexuality, client, clinical practice, therapy, solution focused

  17. Inventing the Pedophile in the Journal of Homosexuality.

    Science.gov (United States)

    Zaborskis, Mary

    2016-01-01

    This article serves as one of the supplementary pieces of this special issue on "Mapping Queer Bioethics," in which we take a solipsistic turn to "map" the Journal of Homosexuality itself. Here, the author examines one of the most controversial moments in the history of the journal, whereby a contributor was subject to governmental and popular rebuke for his scholarship on pederasty, pedophilia, and underage queer sexuality. In a chronological and intellectual appraisal of this pedophilia-themed text, the author asks us to recalibrate the disquietude we posit when same-sex affection, youthful sexuality, and sexual abuse are in close proximity.

  18. "Unthinkable" parenthoods: homosexual, transvestite, and transsexual mothers and fathers

    Directory of Open Access Journals (Sweden)

    Elizabeth Zambrano

    Full Text Available The growing number of families formed by homosexual, transvestite, and transsexual fathers/mothers has not only become a social, but also socio-anthropological fact, requiring traditional convictions to be rethought. This paper aims at demonstrating how a traditional model of family - that is, a "normal" family - has been able to influence the construction of parenthoods considered, until recently, unthinkable, whether social or legally. I therefore believe that it is time to face new demands and deconstruct former certainties of Anthropology, Psychology and Psychoanalysis, and Law, so that these new families may find their place in society.

  19. Fag Men: Mad Men, Homosexuality and Televisual Style

    OpenAIRE

    Wallace, Lee

    2012-01-01

    Among the many retro-fittings achieved by Mad Men—Matthew Weinerʼs still unfurling television series set in the advertising world of the early 1960s—is the representation of the homosexual closet as a thing of the past. This essay approaches Mad Men’s account of the homophobic past in order to think about sexuality and televisual style. A landmark programme coterminous with American television transferring from analogue to digital signal, Mad Men allegorizes another moment in television histo...

  20. People at High Risk of Developing Flu-Related Complications

    Science.gov (United States)

    ... Influenza Types Seasonal Avian Swine Variant Pandemic Other People at High Risk of Developing Flu–Related Complications ... related complications if they get sick with influenza. People at High Risk for Developing Flu-Related Complications ...

  1. [Seronegative antiphospholipid syndrome, catastrophic syndrome, new anticoagulants: learning from a difficult case report].

    Science.gov (United States)

    Joalland, F; de Boysson, H; Darnige, L; Johnson, A; Jeanjean, C; Cheze, S; Augustin, A; Auzary, C; Geffray, L

    2014-11-01

    The diagnosis of the antiphospholipid syndrome (APS) is based on clinical and biological criteria including the persistent presence of antiphospholipid antibodies and thrombotic events or pregnancy morbidity. Heparins relayed by vitamin K antagonists (VKA) are the gold standard treatment for thrombosis. We report a 17-year-old man who presented with an initially seronegative antiphospholipid syndrome, in whom the diagnosis was late, only obtained after anticoagulation withdrawing, when a catastrophic antiphospholipid syndrome (CAPS) with cutaneous lesions and disseminated intravascular coagulation syndrome occurred. For personal convenience, this patient was initially treated with fondaparinux followed by a new oral anticoagulant (rivaroxaban) before to return to the conventional VKA treatment. The "seronegative" APS is a controversial concept reflecting the heterogeneity of antigenic targets for aPL. This diagnosis may be considered after a rigorous work-up, with the help of haemostasis laboratories testing new emerging aPL assays. In APS, the new anticoagulants represent an attractive option needing nevertheless prospective studies to evaluate their safety and efficacy. Lupus anticoagulant detection in patients treated by new oral anticoagulants is not easy by usually recommended coagulation tests. Copyright © 2014. Published by Elsevier SAS.

  2. Reports of Parental Maltreatment during Childhood in a United States Population-Based Survey of Homosexual, Bisexual, and Heterosexual Adults.

    Science.gov (United States)

    Corliss, Heather L.; Cochran, Susan D.; Mays, Vickie M.

    2002-01-01

    A study examined childhood maltreatment among 2917 heterosexual, homosexual, and bisexual adults. Homosexual/bisexual men reported higher rates than heterosexual men of childhood emotional and physical maltreatment by their mothers and major physical maltreatment by their fathers. Homosexual/bisexual women reported higher rates of major physical…

  3. Acceptance of homosexuality through education? Investigating the role of education, family background and individual characteristics in the United Kingdom

    NARCIS (Netherlands)

    la Roi, Chaïm; Mandemakers, Jornt

    Higher educated people tend to be more accepting of homosexuality than lower educated people. This has inspired claims that education leads to a higher acceptance of homosexuality. Alternatively, the association between education and acceptance of homosexuality could be confounded by (un)observed

  4. The diagnostic status of homosexuality in DSM-III: a reformulation of the issues.

    Science.gov (United States)

    Spitzer, R L

    1981-02-01

    In 1973 homosexuality per se was removed from the DSM-II classification of mental disorders and replaced by the category Sexual Orientation Disturbance. This represented a compromise between the view that preferential homosexuality is invariably a mental disorder and the view that it is merely a normal sexual variant. While the 1973 DSM-II controversy was highly public, more recently a related but less public controversy involved what became the DSM-III category of Ego-dystonic Homosexuality. The author presents the DSM-III controversy and a reformulation of the issues involved in the diagnostic status of homosexuality. He argues that what is at issue is a value judgment about heterosexuality, rather than a factual dispute about homosexuality.

  5. Narcissism and self-esteem among homosexual and heterosexual male students.

    Science.gov (United States)

    Rubinstein, Gidi

    2010-01-01

    According to orthodox psychoanalytical theory, narcissism and homosexuality are strongly associated. This association played a major role in pathologizing homosexuality. The present study compared self-esteem and two measures of narcissism among 90 homosexual and 109 heterosexual male students, who filled in a demographic questionnaire, Rosenberg's Self-Esteem Scale, the Narcissistic Personality Inventory, and the Pathological Narcissism Inventory, which addresses both grandiose and vulnerable subtypes of narcissism. The hypothesis, which is based on the Freudian connection between narcissism and homosexuality, is supported by the results, indicating that the homosexual students score higher in both measures of narcissism and lower on the self-esteem measure, compared to their heterosexual counterparts. Intra-psychic, as well as environmental, interpretations of the results are suggested in the discussion.

  6. Is Gaydar Affected by Attitudes Toward Homosexuality? Confidence, Labeling Bias, and Accuracy.

    Science.gov (United States)

    Brewer, Gayle; Lyons, Minna

    2017-01-01

    Previous research has largely ignored the relationship between sexual orientation judgement accuracy, confidence, and attitudes toward homosexuality. In an online study, participants (N = 269) judged the sexual orientation of homosexual and heterosexual targets presented via a series of facial photographs. Participants also indicated their confidence in each judgment and completed the Modern Homonegativity Scale (Morrison & Morrison, 2002). We found that (1) homosexual men and heterosexual women were more accurate when judging photographs of women as opposed to photographs of men, and (2) in heterosexual men, negative attitudes toward homosexual men predicted confidence and bias when rating men's photographs. Findings indicate that homosexual men and heterosexual women are similar in terms of accuracy in judging women's sexuality. Further, especially in men, homophobia is associated with cognitive biases in labeling other men but does not have a relationship with increased accuracy.

  7. Comparison of seronegative and seropositive rheumatoid arthritis with regard to some clinical characteristics.

    Science.gov (United States)

    Sahatçiu-Meka, Vjollca; Izairi, Remzi; Rexhepi, Sylejman; Manxhuka-Kerliu, Suzana

    2009-01-01

    The aim of this study is to establish a scientific comparative analysis between seronegative and seropositive rheumatoid arthritis (RA), with regard to some clinical characteristics. The studied group consisted of RA seronegative patients with titters lower then 1:64 defined by Rose-Waaler test, while the control group consisted of RA seropositive patients with titters of 1:64 or higher. Examinees all belonged to the 2nd and 3rd functional classes according to ARA criteria, were between 25-60 years of age (Xb = 49.96), with disease duration between 1-27 years (Xbox = 6.41). In the disease onset most frequently affected joints were metacarpophalangeal (MCP) and proximal interphalangeal (PIP) joint of the hands, almost equally represented with regard to sero-status and sex. During the examination seropositive patients showed a higher presence of inflamation of peripheral joints of hand and foot, but only the presence of PIP of the hands was statistically significant (chi2 = 15.63, p < 0.01). Knees, talocrural joints and elbows were more frequently affected in seropositive patients, whereas humeroscapular, coxofemoral and sacroiliacal joints were more frequently affected in seronegative patients, but without significant statistical difference with regard to sero-status. The presence of affected PIP of the hands (chi2 = 9.96, p < 0.01) and knees (chi2 = 4.17, p < 0.05) with regard to sex was statistically significant in seropositive female patients, as well as the presence of atacked PIP of the hands (chi2 = 6.08, p < 0.05), and cervical vertebrae (chi2 = 6.00, p < 0.05) in seropositive male patients. There were some differences between groups with regard to sex in metatarsophalangealjoints (MTP), PIP of the foot, and other joints, but without any statistical significance. In both subsets statistically significant domination was found in affected second (chi2 = 20.85, p < 0.01) and third (chi2 = 15.70, p < 0.01) fingers of the PIP level of hands and third finger (chi2

  8. An assessment of high risk sexual behaviour and HIV transmission among migrant oil workers in the Niger Delta area of Nigeria.

    Science.gov (United States)

    Nwauche, C A; Akani, C I

    2006-06-01

    A cross--sectional behavioural survey undertaken amongst migrant oil-workers of an oil exploration outfit operating in the Niger-Delta of Nigeria with the aim of assessing the interplay of migrancy, high-risk sexual behaviour and HIV transmission. A total of 300 randomly selected migrant oil workers were assessed using structured questionnaires to evaluate key high - risk sexual behavioral parameters such as multiplicity of sexual partners, bisexuality (closet homosexuality), high grade sexual behaviour and lesbianism. Sampling period was two months with a control cohort of 200. The prevalence of high risk sexual behaviour (HRSB) amongst the migrant oil workers was found to be 7.7% while low-risk sexual behaviour (LRSB) was 92.3%. There was no record of HRSB in the control group. We did not also encounter any lesbian sexual orientation in this study. The distribution of HRSB amongst the migrant oil workers showed that the commonest variety was bisexuality (closet homosexuality) with 10(43.5%) followed by high-risk sexual behaviour 7(30.4%), while the least common was multiplicity of sexual partners with 6 (26.1%). Furthermore, majority of these individuals 19 (82.6%) were above the age of 35 years. The index of condom-use and acceptance was high. Here 14 (60.9%) found condom-use convenient while 13 (56.5%) regularly used the condom. This study confirms the existence of HRSB among migrant oil workers in the Niger delta. It is therefore advisable to focus interventionist and prevention programmes on this group which appear to be pivotal in the transmission and spread of HIV/AIDS in this environment.

  9. Diagnostic value of anti-annexin A5 antibodies in seropositive versus seronegative antiphospholipid syndrome patients

    Directory of Open Access Journals (Sweden)

    Gihan Omar

    2018-04-01

    Full Text Available Background: Current laboratory criteria for antiphospholipid syndrome (APS classification recommend testing positive for antiphospholipid (aPL antibodies. However, there appears to be a subset of patients with classical APS manifestations who test negative. Aim of the work: To analyze the potential clinical usefulness of testing for anti-annexin A5 antibodies in patients with APS and to study the effectiveness of testing for non-criteria aPLs in an attempt to increase the diagnostic yield, particularly in seronegative APS. Patients and methods: 60 APS patients were divided into two groups; 30 seropositive (SP-APS (group I and 30 age and sex matched seronegative (sN-APS testing negative for aPL antibodies. Serum assay for detection of isotypes of anti-annexin A5 antibodies (IgG and IgM were conducted. Results: The mean age of the patients was 32.9 ± 5.8 years, female:male 57:3 and disease duration in SP-APS versus sN-APS (10.17 ± 4.9 years versus 9.6 ± 5.5 years respectively. Secondary APS was present in 16(53.3% patients in group I compared to 3(10% in group II (p < 0.0001. The mean anti-AnxA5 IgG level was 10.7 ± 5.6 U/ml and IgM was 11.2 ± 7.1 U/ml and were comparable between the 2 groups. The obstetric and thrombotic morbidity had no significant differences between SP and sN-APS. The IgG and IgM levels significantly correlated with the pregnancy morbidity, venous and arterial thrombosis events and showed reasonable sensitivities in their prediction (IgG:71.2%,72.8% and 75.8%; IgM: 68%,67.8% and 71.4% respectively and specificities (IgG:75.9%,77.8% and 81.5%; IgM: 70.9%,73.1% and 73.7% respectively. Conclusion: anti-annexinA5 antibodies are promising for detecting obstetric and thrombotic morbidity in both SP- and sN-APS patients. Keywords: Antiphospholipid syndrome, Seropositive APS (SP-APS, Seronegative APS (sN-APS, Anti-annexin A5 antibodies

  10. The Psychosis High-Risk State

    Science.gov (United States)

    Fusar-Poli, Paolo; Borgwardt, Stefan; Bechdolf, Andreas; Addington, Jean; Riecher-Rössler, Anita; Schultze-Lutter, Frauke; Keshavan, Matcheri; Wood, Stephen; Ruhrmann, Stephan; Seidman, Larry J.; Valmaggia, Lucia; Cannon, Tyrone; Velthorst, Eva; De Haan, Lieuwe; Cornblatt, Barbara; Bonoldi, Ilaria; Birchwood, Max; McGlashan, Thomas; Carpenter, William; McGorry, Patrick; Klosterkötter, Joachim; McGuire, Philip; Yung, Alison

    2014-01-01

    Context During the past 2 decades, a major transition in the clinical characterization of psychotic disorders has occurred. The construct of a clinical high-risk (HR) state for psychosis has evolved to capture the prepsychotic phase, describing people presenting with potentially prodromal symptoms. The importance of this HR state has been increasingly recognized to such an extent that a new syndrome is being considered as a diagnostic category in the DSM-5. Objective To reframe the HR state in a comprehensive state-of-the-art review on the progress that has been made while also recognizing the challenges that remain. Data Sources Available HR research of the past 20 years from PubMed, books, meetings, abstracts, and international conferences. Study Selection and Data Extraction Critical review of HR studies addressing historical development, inclusion criteria, epidemiologic research, transition criteria, outcomes, clinical and functional characteristics, neurocognition, neuroimaging, predictors of psychosis development, treatment trials, socioeconomic aspects, nosography, and future challenges in the field. Data Synthesis Relevant articles retrieved in the literature search were discussed by a large group of leading worldwide experts in the field. The core results are presented after consensus and are summarized in illustrative tables and figures. Conclusions The relatively new field of HR research in psychosis is exciting. It has the potential to shed light on the development of major psychotic disorders and to alter their course. It also provides a rationale for service provision to those in need of help who could not previously access it and the possibility of changing trajectories for those with vulnerability to psychotic illnesses. PMID:23165428

  11. Homosexuality and scientific evidence: On suspect anecdotes, antiquated data, and broad generalizations.

    Science.gov (United States)

    Kinney, Robert L

    2015-11-01

    The American Psychiatric Association and the American Psychological Association have suggested for many years now that there is significant empirical evidence supporting the claim that homosexuality is a normal variant of human sexual orientation as opposed to a mental disorder. This paper summarizes and analyzes that purported scientific evidence and explains that much (if not all) of the evidence is irrelevant and does not support the homosexuality-is-not-a-mental-disorder claim. As a result of their deficiencies and arbitrariness, the credibility those two groups that are typically deemed authoritative and trustworthy is called into question. Lay summary: At one time, homosexuality was considered to be mentally disordered. Since the 1970s, however, major medical associations in the U.S. have labeled homosexuality as a normal counterpart of heterosexuality. Those medical associations have proposed that their homosexuality-is-normal claim is based on "scientific evidence." This article critically reviews that "scientific evidence" and finds that much of their literature does not support the claim that homosexuality is normal. This article suggests that instead of supporting their claim with scientific evidence, those major medical associations arbitrarily label homosexuality as normal.

  12. A systematic review of instruments that measure attitudes toward homosexual men.

    Science.gov (United States)

    Grey, Jeremy A; Robinson, Beatrice Bean E; Coleman, Eli; Bockting, Walter O

    2013-01-01

    Scientific interest in the measurement of homophobia and internalized homophobia has grown over the past 30 years, and new instruments and terms have emerged. To help researchers with the challenging task of identifying appropriate measures for studies in sexual-minority health, we reviewed measures of homophobia published in the academic literature from 1970 to 2012. Instruments that measured attitudes toward male homosexuals/homosexuality or measured homosexuals' internalized attitudes toward homosexuality were identified using measurement manuals and a systematic review. A total of 23 instruments met criteria for inclusion, and their features were summarized and compared. All 23 instruments met minimal criteria for adequate scale construction, including scale development, sampling, reliability, and evidence of validity. Validity evidence was diverse and was categorized as interaction with gay men, HIV/AIDS variables, mental health, and conservative religious or political beliefs. Homophobia was additionally correlated with authoritarianism and bias, gender ideology, gender differences, and reactions to homosexual stimuli. Internalized homophobia was validated by examining relationships with disclosing one's homosexuality and level of homosexual identity development. We hope this review will make the process of instrument selection more efficient by allowing researchers to easily locate, evaluate, and choose the proper measure based on their research question and population of interest.

  13. Experiences of homosexual patients' access to primary health care services in Umlazi, KwaZulu-Natal.

    Science.gov (United States)

    Cele, Nokulunga H; Sibiya, Maureen N; Sokhela, Dudu G

    2015-09-28

    Homosexual patients are affected by social factors in their environment, and as a result may not have easy access to existing health care services. Prejudice against homosexuality and homosexual patients remains a barrier to them seeking appropriate healthcare. The concern is that lesbians and gays might delay or avoid seeking health care when they need it because of past discrimination or perceived homophobia within the health care thereby putting their health at risk. The aim of the study was to explore and describe the experiences of homosexual patients utilising primary health care (PHC) services in Umlazi in the province ofKwaZulu-Natal (KZN). A qualitative, exploratory, descriptive study was conducted which was contextual innature. Semi-structured interviews were conducted with 12 participants. The findings of this study were analysed using content analysis. Two major themes emerged from the data analysis, namely, prejudice against homosexual patients by health care providers and other patients at the primary health care facilities, and, homophobic behaviour from primary health care personnel. Participants experienced prejudice and homophobic behaviour in the course of utilising PHC clinics in Umlazi, which created a barrier to their utilisation of health services located there. Nursing education institutions, in collaboration with the National Department of Health, should introduce homosexuality and anti-homophobia education programmes during the pre-service and in-service education period. Such programmes will help to familiarise health care providers with the health care needs of homosexual patients and may decrease homophobic attitudes.

  14. Predictive markers of survival in HIV-seropositive and HIV-seronegative Tanzanian patients with extrapulmonary tuberculosis

    NARCIS (Netherlands)

    Richter, C.; Koelemay, M. J.; Swai, A. B.; Perenboom, R.; Mwakyusa, D. H.; Oosting, J.

    1995-01-01

    Prediction of survival in Tanzanian patients with extrapulmonary tuberculosis (TB). To evaluate the prognostic value of clinical and laboratory parameters on survival in human immunodeficiency virus (HIV) seropositive and HIV seronegative patients with extrapulmonary TB. Over an 8-month period 192

  15. FDG-PET/CT Findings in a Patient with Polymyalgia Rheumatica and Accompanying Remitting Seronegative Symmetrical Synovitis with Pitting Edema

    DEFF Research Database (Denmark)

    Emamifar, Amir; Hess, Søren; Jørgensen, Erik Øster

    2016-01-01

    Background: Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) is a rare, but well-defined syndrome comprising polyarthritis with symmetrical synovitis of the small joints in hands and feet accompanied by marked pitting edema. It is often considered a paraneoplastic syndrome...

  16. Syndrome of remitting seronegative symmetrical synovitis with pitting edema: A case series

    Directory of Open Access Journals (Sweden)

    A N Varshney

    2015-01-01

    Full Text Available Remitting Seronegative Symmetrical Synovitis with Pitting Edema (RS3PE is a rare clinical entity that is easily missed due to lack of knowledge. It was formerly considered as a subset of rheumatoid arthritis (RA, but is now regarded as a distinct disease/syndrome. The diagnosis of RS3PE is not easy, as it is always hindered by the lack of definite diagnostic criteria and presence of other much common rheumatological disorders that mimic it. We report a series of seven cases that attended our clinic in the last year, which highlight the salient features of the disease. The disease was found to have a heterogeneous presentation. Immunogenetic, clinical, laboratory, radiological, and possible etiological factors and associations with the neoplasm are described, as also other peculiar presentations. Finally, a comparison with other common rheumatological disorders is made to alert the clinician about this rare, but easily treatable disease.

  17. Association of Remitting Seronegative Symmetrical Synovitis with Pitting Edema, Polymyalgia Rheumatica, and Adenocarcinoma of the Prostate

    DEFF Research Database (Denmark)

    Emamifar, Amir; Hess, Soeren; Gildberg-Mortensen, Rannveig

    2016-01-01

    BACKGROUND Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) is a rare condition that occurs in elderly individuals. It can present alone or in association with various rheumatic or malignant diseases. CASE REPORT An 83-year-old man presented with anemia, hyper......-sedimentation, and pitting edema of the back of the hands. The patient complained of pain and stiffness of the shoulder and hip girdles, especially in the morning. He was previously diagnosed with adenocarcinoma of the prostate. After 3 years of watchful waiting, treatment with goserelin, a gonadotropin releasing hormone...... of our knowledge, this is the first report of a case of RS3PE that presented twice with 2 different diagnoses in the same patient....

  18. Syndrome of remitting seronegative symmetrical synovitis with pitting edema: a case series.

    Science.gov (United States)

    Varshney, A N; Singh, N K

    2015-01-01

    Remitting Seronegative Symmetrical Synovitis with Pitting Edema (RS3PE) is a rare clinical entity that is easily missed due to lack of knowledge. It was formerly considered as a subset of rheumatoid arthritis (RA), but is now regarded as a distinct disease/syndrome. The diagnosis of RS3PE is not easy, as it is always hindered by the lack of definite diagnostic criteria and presence of other much common rheumatological disorders that mimic it. We report a series of seven cases that attended our clinic in the last year, which highlight the salient features of the disease. The disease was found to have a heterogeneous presentation. Immunogenetic, clinical, laboratory, radiological, and possible etiological factors and associations with the neoplasm are described, as also other peculiar presentations. Finally, a comparison with other common rheumatological disorders is made to alert the clinician about this rare, but easily treatable disease.

  19. Seronegative Neuromyelitis Optica Spectrum - The challenges on disease definition and pathogenesis

    Directory of Open Access Journals (Sweden)

    Douglas Kazutoshi Sato

    2014-06-01

    Full Text Available Neuromyelitis optica spectrum disorders (NMOSD are characterized by severe optic neuritis and/or longitudinally extensive transverse myelitis, and some brain lesions are also unique to NMOSD. Serum autoantibodies against aquaporin-4 (AQP4 are detected in most cases of NMOSD. However, some patients with NMOSD remain seronegative despite repetitive testing during attacks with highly sensitive cell-based assays. The differential diagnosis of NMOSD is not restricted to multiple sclerosis and it includes many diseases that can produce longitudinally extensive myelitis and/or optic neuritis. We review the clinical features, imaging, and laboratory findings that can be helpful on the diagnostic work-up, discuss the differences between AQP4 antibody positive and negative patients with NMOSD, including features of NMOSD with antibodies against myelin oligodendrocyte glycoprotein.

  20. Seronegative neuromyelitis optica spectrum disorder patients diagnosed using new diagnostic criteria.

    Science.gov (United States)

    Uzawa, Akiyuki; Mori, Masahiro; Uchida, Tomohiko; Masuda, Hiroki; Ohtani, Ryohei; Kuwabara, Satoshi

    2016-09-01

    Recently, new diagnostic criteria for neuromyelitis optica spectrum disorders (NMOSD) were published. Our primary aim was to evaluate the usefulness of the new diagnostic criteria in anti-aquaporin 4 (AQP4) antibody-negative cases. Consecutive 471 patients whose anti-AQP4 antibody was measured at Chiba University were reviewed. Four anti-AQP4 antibody negative-patients, who fulfilled the new diagnostic criteria for NMOSD but not 2006 diagnostic criteria for neuromyelitis optica (NMO), were identified. They showed high cerebrospinal fluid interleukin-6 and glial fibrillary acidic protein levels, an absence of oligoclonal bands and/or cloud-like enhancement on magnetic resonance imaging, which are compatible findings for NMO. The new diagnostic criteria are clinically useful in seronegative NMOSD. © The Author(s), 2015.

  1. Peripheral involvement of the joint in seronegative spondylarthritis; Periphere Gelenkbeteiligung bei seronegativen Spondarthritiden

    Energy Technology Data Exchange (ETDEWEB)

    Lingg, G.; Soltesz, I. [Rheumazentrum Bad Kreuznach (Germany). Zentrales Roentgeninstitut

    1997-10-01

    The subjects of this contributions have been restricted to the peripheral manifestations of seronegative spondylarthrosis, for reasons of conciseness and clearness. The most frequent occurrences discussed are psoriasis arthritis and, a little bit less frequent, peripheral involvement of the joint in ancylosing spondylitis and Reiter syndrome, as well as enteropathic spondylarthrosis. (orig./AJ) [Deutsch] Als Thema dieser Veroeffentlichung wurden aus Gruenden der Kuerze und der Uebersichtlichkeit aber nur die peripheren Manifestationen der seronegativen Spondarthropathien gewaehlt. Hier wiederum haben wir es am haeufigsten mit der Psoriasisarthritis und etwas seltener mit der peripheren Gelenkbeteiligung bei der Bechterew`schen Erkrankung und der Reiter`schen Erkrankung sowie der enteropathischen Spondarthritiden zu tun. (orig./AJ)

  2. Fecundity of paternal and maternal non-parental female relatives of homosexual and heterosexual men.

    Directory of Open Access Journals (Sweden)

    Andrea Camperio Ciani

    Full Text Available A variety of social, developmental, biological and genetic factors influence sexual orientation in males. Thus, several hypotheses have attempted to explain the sustenance of genetic factors that influence male homosexuality, despite decreased fecundity within the homosexuals. Kin selection, the existence of maternal effects and two forms of balancing selection, sexually antagonistic selection and overdominance, have been proposed as compensatory mechanisms for reduced homosexual fecundity. Here, we suggest that the empirical support for kin selection and maternal effects cannot account for the low universal frequency and stability of the distribution of homosexuals. To identify the responsible compensatory mechanism, we analyzed fecundity in 2,100 European female relatives, i.e., aunts and grandmothers, of either homosexual or heterosexual probands who were matched in terms of age, culture and sampling strategy. Female relatives were chosen to avoid the sampling bias of the fraternal birth order effect, which occurs when indirectly sampling mothers though their homosexual sons. We observed that the maternal aunts and grandmothers of homosexual probands were significantly more fecund compared with the maternal aunts and maternal grandmothers of the heterosexual probands. No difference in fecundity was observed in the paternal female lines (grandmothers or aunts from either of the two proband groups. Moreover, due to the selective increase in maternal female fecundity, the total female fecundity was significantly higher in homosexual than heterosexual probands, thus compensating for the reduced fecundity of homosexuals. Altogether, these data support an X-linked multi-locus sexually antagonistic hypothesis rather than an autosomal multi-locus overdominance hypothesis.

  3. Seronegative Neuromyelitis Optica Spectrum Disorder following Exposure to Hepatitis B Vaccination

    Directory of Open Access Journals (Sweden)

    Richard Heekin

    2015-04-01

    Full Text Available Controversy exists regarding a potential link between exposure to recombinant hepatitis B vaccine (HBV and central nervous system demyelinating diseases. Here, we present a case of seronegative neuromyelitis optica spectrum disorder (NMOSD following exposure to HBV. A 28-year-old man developed painful eye movements 11 days after exposure to HBV. Within 24 h, he experienced vision loss, ascending numbness, and ataxia. T-spine MRI showed a cord lesion spanning T6-T9. Brain MRI showed bilateral optic nerve contrast enhancement and a right-sided internal capsule lesion. Cerebrospinal fluid analysis was normal, including negative oligoclonal bands and normal IgG index. AQP4-IgG serology was negative. The patient's visual symptoms improved after treatment with steroids and plasma exchange. He received plasma exchange weekly for 4 weeks with decreased numbness and tingling as well as improved coordination. Treatment with mycophenolate mofetil was started, and the patient remains clinically stable with near resolution of his prior symptoms. Neuromyelitis optica is characterized by optic neuritis and/or longitudinally extensive transverse myelitis. While our patient tested seronegative for AQP4-IgG (which remains negative in 10-50% of NMOSD cases, despite testing with the most sensitive assays available, he did meet NMOSD diagnostic criteria. In a literature review, we found 7 cases of NMOSD onset or relapse associated with exposure to various vaccines, but to our knowledge this represents the first published report of NMOSD onset following exposure to HBV. While causality between vaccination and CNS demyelinating disease remains elusive, it is important to report these cases to help develop safer vaccinations and provoke further inquiry into the pathogenesis of NMOSD.

  4. Seronegative Celiac Disease and Immunoglobulin Deficiency: Where to Look in the Submerged Iceberg?

    Directory of Open Access Journals (Sweden)

    Floriana Giorgio

    2015-09-01

    Full Text Available In the present narrative review, we analyzed the relationship between seronegative celiac disease (SNCD and immunoglobulin deficiencies. For this purpose, we conducted a literature search on the main medical databases. SNCD poses a diagnostic dilemma. Villous blunting, intraepithelial lymphocytes (IELs count and gluten “challenge” are the most reliable markers. Immunohistochemistry/immunofluorescence tissue transglutaminase (tTG-targeted mucosal immunoglobulin A (IgA immune complexes in the intestinal mucosa of SNCD patients may be useful. In our experience, tTG-mRNA was similarly increased in seropositive celiac disease (CD and suspected SNCD, and strongly correlated with the IELs count. This increase is found even in the IELs’ range of 15–25/100 enterocytes, suggesting that there may be a “grey zone” of gluten-related disorders. An immune deregulation (severely lacking B-cell differentiation underlies the association of SNCD with immunoglobulin deficiencies. Therefore, CD may be linked to autoimmune disorders and immune deficits (common variable immunodeficiency (CVID/IgA selective deficiency. CVID is a heterogeneous group of antibodies dysfunction, whose association with CD is demonstrated only by the response to a gluten-free diet (GFD. We hypothesized a familial inheritance between CD and CVID. Selective IgA deficiency, commonly associated with CD, accounts for IgA-tTG seronegativity. Selective IgM deficiency (sIgMD is rare (<300 cases and associated to CD in 5% of cases. We diagnosed SNCD in a patient affected by sIgMD using the tTG-mRNA assay. One-year GFD induced IgM restoration. This evidence, supporting a link between SNCD and immunoglobulin deficiencies, suggests that we should take a closer look at this association.

  5. Containing a contagion : crime and homosexuality in post-revolutionary Mexico City

    OpenAIRE

    Cook, Stephen Sherrard

    2008-01-01

    Primarily based upon archival resources at the Archivo Histórico del Distrito Federal (AHDF) and the Archivo General de la Nación (AGN) in Mexico City, this thesis is a social and cultural history of the criminalization and punishment of homosexuality during the 1920s and 1930s in Mexico City. The bulk of the primary historical research is based upon two separate spheres of homosexual-related criminal cases, adult and juvenile homosexual 'criminal' cases. The Archivo Histórico houses adult cr...

  6. "Every jack to his trade?": power, identity and market segmentation in the homosexual movement

    Directory of Open Access Journals (Sweden)

    Isadora Lins França

    Full Text Available The present article aims at exploring the relations between the homosexual movement and the segmented consumption market directed at such public in São Paulo. Starting with the social drama analyzed in the text, which involves militant homosexuals and transvestites, the so-called actors of such segmented market, and the attending public, we intend to delineate ways to understand these relations, as well as some processes related to the constitution of the political subject of the homosexual movement in a context of both multiplication of identifying categories and destabilization of this subject.

  7. Identifying With a Stereotype: The Divergent Effects of Exposure to Homosexual Television Characters.

    Science.gov (United States)

    McLaughlin, Bryan; Rodriguez, Nathian S

    2017-01-01

    Scholars examining homosexual television characters have typically come to one of two conclusions: either exposure to homosexual characters can lead to increased acceptance, or homosexual characters serve to reaffirm negative stereotypes. We seek to bridge these two bodies of research by introducing the concept of stereotyped identification-the idea that cognitively and emotionally identifying with fictional characters can increase acceptance of minorities, while reinforcing implicit stereotypes about how they look, act, and talk. Results from our national survey (N = 972) offer support for this hypothesis.

  8. Japan's progressive sex: male homosexuality, national competition, and the cinema.

    Science.gov (United States)

    Hall, J M

    2000-01-01

    This essay serves as a broad investigation of the origins of what came to be called the "gay boom" in 1990's Japanese cinema: a culmination of print media, television, and especially films which made the gay male not merely a visible (political) subject but also the site of displaced contestations of gendered (female) desire. The most visible transnational signifier of the "gay boom" was the 1992 film Okoge, a film which, in keeping with a Japanese trend which relocates the gay male as a safe displacement of female desire, posits the heterosexual female as the audience's point of identification in a film about the lives of gay Japanese men. Using this as a starting point, this essay seeks to explore how male homosexuality and gender construction operate within both Japanese nationalism and the transnational discourse of Japanese cinema's dissemination.

  9. Challenging the Black Church Narrative: Race, Class, and Homosexual Attitudes.

    Science.gov (United States)

    Irizarry, Yasmiyn A; Perry, Ravi K

    2018-01-01

    In recent years, scholars have pointed to the Black church as the driving force behind Blacks' more conservative lesbian, gay, bisexual, and transgendered (LGBT) attitudes. Although evidence suggests a robust association between religiosity and LGBT attitudes, contemporary scholarship has not examined the role of class or the extent to which religiosity actually explains these trends. Using the 2004-2014 waves of the General Social Survey, we find that class moderates in the effect of race on negative LGBT attitudes, resulting in a noticeably larger gap between middle-class Blacks and Whites than in the top or the bottom of the class distribution. Although religiosity and moralization explain a portion of racial differences in homosexual attitudes across class groups, we find that neither fully accounts for the more conservative attitudes of the Black middle class. We conclude by discussing the shortcomings of these narratives for understanding Blacks' more conservative LGBT attitudes.

  10. The Bible on homosexuality: exploring its meaning and authority.

    Science.gov (United States)

    Locke, Kenneth A

    2004-01-01

    Even within this secular age the Bible is still referred to in controversial matters of ethics and morality. Nowhere is this more evident than in the debate over the acceptability or unacceptability of homosexuality. This paper evaluates the Bible's statements on homoeroticism by explaining their historical, cultural, linguistic and narrative contexts. It finds that while the Bible is silent on matters of orientation, it does seem to adopt a negative attitude toward at least male same-sex sexual encounters. This finding, however, is in itself irrelevant unless it is related to how communities use and make sense of the Bible. There are many biblical prohibitions and condemnations that are ignored by even the most fundamentalist Christian groups. Whether the biblical passages on homoeroticism are treated authoritatively or not rests ultimately on the outlook and interpretive framework used by a Christian community to make coherent sense of the Bible.

  11. Competing Claims: Religious Affiliation and African Americans' Intolerance of Homosexuals.

    Science.gov (United States)

    Ledet, Richard

    2017-01-01

    Literature on religion and political intolerance indicates competing expectations about how Black Protestant church affiliation affects African Americans' attitudes about civil liberties. On the one hand, Black Protestant theology emphasizes personal freedom and social justice, factors generally linked to more tolerant attitudes. On the other hand, Black Protestants tend to be conservative on family and social issues, factors often linked to intolerance of gays and lesbians. Data from the General Social Survey are used to examine the influence of religious group identification, as well as other relevant aspects of religiosity, on political intolerance among African Americans. Results indicate that although other aspects of religion (beliefs and behaviors) help explain variation in political intolerance, Black Protestant church affiliation has no relationship with attitudes about the civil liberties of homosexuals. However, additional tests show that Black Protestant church affiliation significantly predicts intolerance of other target groups (atheists and racists).

  12. Sexual and romantic jealousy in heterosexual and homosexual adults.

    Science.gov (United States)

    Harris, Christine R

    2002-01-01

    Several theorists have claimed that men are innately more upset by a mate's sexual infidelity and women are more upset by a mate's emotional infidelity because the sexes faced different adaptive problems (for men, cuckoldry; for women, losing a mate's resources). The present work examined this theory of jealousy as a specific innate module in 196 adult men and women of homosexual and heterosexual orientations. As in previous work, heterosexuals' responses to a forced-choice question about hypothetical infidelity yielded a gender difference. However no gender differences were found when participants recalled personal experiences with a mate's actual infidelity. Men and women, regardless of sexual orientation, on average focused more on a mate's emotional infidelity than on a mate's sexual infidelity. Responses to hypothetical infidelity were uncorrelated with reactions to actual infidelity. This finding casts doubt on the validity of the hypothetical measures used in previous research.

  13. [Targeting high-risk drugs to optimize clinical pharmacists' intervention].

    Science.gov (United States)

    Mouterde, Anne-Laure; Bourdelin, Magali; Maison, Ophélie; Coursier, Sandra; Bontemps, Hervé

    2016-12-01

    By the Order of 6 April 2011, the pharmacist must validate all the prescriptions containing "high-risk drugs" or those of "patients at risk". To optimize this clinical pharmacy activity, we identified high-risk drugs. A list of high-risk drugs has been established using literature, pharmacists' interventions (PI) performed in our hospital and a survey sent to hospital pharmacists. In a prospective study (analysis of 100 prescriptions for each high-risk drug selected), we have identified the most relevant to target. We obtained a statistically significant PI rate (P<0.05) for digoxin, oral anticoagulants direct, oral methotrexate and colchicine. This method of targeted pharmaceutical validation based on high-risk drugs is relevant to detect patients with high risk of medicine-related illness. Copyright © 2016 Société française de pharmacologie et de thérapeutique. Published by Elsevier Masson SAS. All rights reserved.

  14. Sero-epidemiological study of Lyme disease among high-risk population groups in eastern Slovakia.

    Science.gov (United States)

    Zákutná, Ľubica; Dorko, Erik; Mattová, Eva; Rimárová, Kvetoslava

    2015-01-01

    IIntroduction and objective. The aim of the presented cross-sectional sero-epidemiological study was to determine the current presence of antibodies against B. burgdorferi s.l. in the high-risk groups of the Slovak population, and to identify potential risk factors to LB infections. A group of 277 agricultural and forestry workers - persons with frequent stay in the countryside and employees of State Border and Customs Police - from years 2011-2012 in the Eastern Slovakia were examined in order to assess the seroprevalence of anti-Borrelia antibodies. Sera were screened by commercial enzyme-linked immunosorbent assay (ELISA). The study subjects completed a questionnaires with general demographic, epidemiological and clinical data. The results were evaluated statistically. A 25.3% presence of positive and 8.7% presence of borderline IgG antibodies was detected in all investigated groups. The seroprevalence of B. burgdorferi s.l. was significantly higher (P<0.05) among the agricultural and forestry workers when compared to employees of State Border and Customs Police. Higher seropositivity was observed in older subjects over 30 years of age (P=0.004) than those who were younger, and also in males (P=0.045). A significant number of persons with rheumatologic conditions was statistically higher (P=0.020) in the group with seropositivity than in the group with seronegativity. The presented study confirms the higher risk of Borrelia infection in individuals with frequent exposure to ticks in eastern Slovakia. The seropositivity tests confirmed the highest seropositivity in agriculture and forestry workers, middle positivity was confirmed among other sector workers, and lowest positivity in policemen and employees of the Customs and Border Inspection. The outputs also simultaneously filling the gap of missing seroprevalence data among these exposed groups.

  15. Cross-cultural differences in female university students' attitudes toward homosexuals: a preliminary study.

    Science.gov (United States)

    Span, Sherry A; Vidal, Lourdes A

    2003-04-01

    62 Caucasian, 61 Hispanic, and 44 Asian female undergraduates completed the Index of Homophobia by Hudson and Ricketts, seven items from the Attitudes Toward Lesbians and Gay Men Scale by Herek, and three questions on Affectional Orientation toward homosexuals from D'Augelli and Rose. Overall, familiarity with homosexuals as measured by self-reported number of homosexual friends correlated negatively with scores on the homophobia measures, but there were no significant differences among the groups' reported number of homosexual friends. Asian students scored significantly higher on the homophobia measures than Caucasian students. Both Asian and Hispanic students endorsed the statement significantly more often than Caucasian students that the university would be better if only heterosexuals attended. No significant differences in scores were found regarding attitudes toward lesbians versus gay men.

  16. Concurrent validity of the Wheeler signs of homosexuality in the Rorschach: P (Ci/Rj).

    Science.gov (United States)

    Stone, N M; Schneider, R E

    1975-12-01

    The Rorschach protocols of 43 males consecutively admitted to a university outpatient clinic were scored for frequency of the 20 Wheeler signs of homosexuality. Based on case history data, patients were assigned to homosexual, sex-role disturbed, or normal-control groups. In addition to the traditional group comparison the results were analyzed to yield P (Ci/Rj); that is, the probability of criterion group membership given test indicator. Both the homosexual and sex-role disturbed group displayed significantly more Wheeler signs than normals. Furthermore, given a Wheeler sign score of 15%, .75 of the predicted-homosexual group would be correctly classified compared to a .21 baserate prediction. It was suggested that expressing results as P (Ci/Rj) provides information more relevant to the clinician than is provided by the traditional practice of reporting significant differences between groups.

  17. "Two men under one cloak"---the Sages permit it: homosexual marriage in Judaism.

    Science.gov (United States)

    Moss, Jacob A; Ulmer, Rivka B Kern

    2008-01-01

    This article examines halakhic (Jewish legal) passages that relate to homosexuality and marriage between two males. The article sets forth the respective positions of contemporary Jewish denominations in regard to homosexual marriage. Homosexual marriage is a case of first impression in Judaism and requires new decisions and new marriage contracts. The principal thesis of the article is that contemporary Judaism can accommodate philosophically--but also legally--a halakhic framework of thinking, same-sex marriage between men. Judaism does not have to opt for the perspectives of Reform and Reconstructionist Judaism, which have, to a major extent, freed themselves from the traditions and rituals of Jewish law. After examining marriage contracts in Rabbinic literature, specific examples are presented of how homosexual marriage between two males may be implemented.

  18. Negotiating homosexual identities: the experiences of men who have sex with men in Guangzhou.

    Science.gov (United States)

    Li, Haochu Howard; Holroyd, Eleanor; Lau, Joseph T F

    2010-05-01

    This paper reports on an ethnographic study of male homosexuality in contemporary Chinese society. The study focused on how men negotiated with the mainstream Chinese heterosexual society and in so doing constructed their sexual identities. The factors found to inform sexual identity were: the cultural imperative of heterosexual marriage, normative family obligations, desired gender roles, emotional experiences and a need for social belonging. The four types of sexual identities constructed included: establishing a deliberate non-homosexual identity, accumulating an individual homosexual identity, forming a collective homosexual identity and adopting a flexible sexual identity. For the men interviewed, sexual identity was both fluid and fragmented, derived from highly personalised negotiations between individualised needs and social and cultural constructs. The analysis is set against the background of China's rapid and recent economic development, shifting national and international social environments and improved access to the Internet.

  19. Homosexuality and scientific evidence: On suspect anecdotes, antiquated data, and broad generalizations

    OpenAIRE

    Kinney, Robert L.

    2015-01-01

    The American Psychiatric Association and the American Psychological Association have suggested for many years now that there is significant empirical evidence supporting the claim that homosexuality is a normal variant of human sexual orientation as opposed to a mental disorder. This paper summarizes and analyzes that purported scientific evidence and explains that much (if not all) of the evidence is irrelevant and does not support the homosexuality-is-not-a-mental-disorder claim. As a resul...

  20. Lymphogranuloma venereum of the rectum in a homosexual man. Case report.

    Science.gov (United States)

    Mindel, A

    1983-01-01

    A male homosexual presented initially with bloody diarrhoea and a swelling in the left groin, which was unsuccessfully treated with erythromycin. Examination in hospital showed a rectal mass and an abscess in the left groin. Histological examination of the rectal mass and a positive lymphogranuloma complement fixation test result confirmed the diagnosis of lymphogranuloma venereum. This disease, although rare, should not be forgotten in the differential diagnosis of rectal problems in male homosexuals. PMID:6850267

  1. Homosexual Behavior in Female Mountain Gorillas: Reflection of Dominance, Affiliation, Reconciliation or Arousal?

    Directory of Open Access Journals (Sweden)

    Cyril C Grueter

    Full Text Available Humans are unique among primates for not only engaging in same-sex sexual acts, but also forming homosexual pair bonds. To shed light on the evolutionary origins of homosexuality, data on the occurrence and contexts of same-sex behavior from nonhuman primates may be of particular significance. Homosexual behavior involving females is poorly researched in most primate taxa, exceptions being Japanese macaques, rhesus macaques, Hanuman langurs and bonobos. We present data on homosexual behavior in female mountain gorillas in the Virunga Volcanoes (Rwanda and test four functional hypotheses, namely reconciliation, affiliation, dominance expression and sexual arousal. Homosexual interactions between females involved both ventro-dorsal and ventro-ventral copulations accompanied by vocalizations and courtship displays. The only sociosexual hypothesis that received partial empirical support is the social status hypothesis, i.e., that mounting reaffirms the dominance hierarchy. There is also some limited evidence that same-sex behavior reflects an overall state of arousal or is triggered via a 'pornographic' effect. An adaptive function of female homosexual behavior is not readily apparent, and we tentatively conclude (until a more rigorous test becomes available that it may simply be related to sexual gratification or that it is an evolutionary by-product of an adaptation.

  2. Beliefs about the Etiology of Homosexuality and about the Ramifications of Discovering Its Possible Genetic Origin

    Science.gov (United States)

    Sheldon, Jane P.; Pfeffer, Carla A.; Jayaratne, Toby Epstein; Feldbaum, Merle; Petty, Elizabeth M.

    2013-01-01

    Homosexuality is viewed by many as a social problem. As such, there has been keen interest in elucidating the origins of homosexuality among many scholars, from anthropologists to zoologists, psychologists to theologians. Research has shown that those who believe sexual orientation is inborn are more likely to have tolerant attitudes toward gay men and lesbians, whereas those who believe it is a choice have less tolerant attitudes. The current qualitative study used in-depth, open-ended telephone interviews with 42 White and 44 Black Americans to gain insight into the public's beliefs about the possible genetic origins of homosexuality. Along with etiological beliefs (and the sources of information used to develop those beliefs), we asked respondents to describe the benefits and dangers of scientists discovering the possible genetic basis for homosexuality. We found that although limited understanding and biased perspectives likely led to simplistic reasoning concerning the origins and genetic basis of homosexuality, many individuals appreciated complex and interactive etiological perspectives. These interactive perspectives often included recognition of some type of inherent aspect, such as a genetic factor(s), that served as an underlying predisposition that would be manifested after being influenced by other factors such as choice or environmental exposures. We also found that beliefs in a genetic basis for homosexuality could be used to support very diverse opinions, including those in accordance with negative eugenic agendas. PMID:17594974

  3. Implicit attitudes towards homosexuality: reliability, validity, and controllability of the IAT.

    Science.gov (United States)

    Banse, R; Seise, J; Zerbes, N

    2001-01-01

    Two experiments were conducted to investigate the psychometric properties of an Implicit Association Test (IAT; Greenwald, McGhee, & Schwartz, 1998) that was adapted to measure implicit attitudes towards homosexuality. In a first experiment, the validity of the Homosexuality-IAT was tested using a known group approach. Implicit and explicit attitudes were assessed in heterosexual and homosexual men and women (N = 101). The results provided compelling evidence for the convergent and discriminant validity of the Homosexuality-IAT as a measure of implicit attitudes. No evidence was found for two alternative explanations of IAT effects (familiarity with stimulus material and stereotype knowledge). The internal consistency of IAT scores was satisfactory (alpha s > .80), but retest correlations were lower. In a second experiment (N = 79) it was shown that uninformed participants were able to fake positive explicit but not implicit attitudes. Discrepancies between implicit and explicit attitudes towards homosexuality could be partially accounted for by individual differences in the motivation to control prejudiced behavior, thus providing independent evidence for the validity of the implicit attitude measure. Neither explicit nor implicit attitudes could be changed by persuasive messages. The results of both experiments are interpreted as evidence for a single construct account of implicit and explicit attitudes towards homosexuality.

  4. Effects of attractiveness and status in dating desire in homosexual and heterosexual men and women.

    Science.gov (United States)

    Ha, Thao; van den Berg, Judith E M; Engels, Rutger C M E; Lichtwarck-Aschoff, Anna

    2012-06-01

    The present study examined partner preferences of homosexual and heterosexual men and woman, focusing on attractiveness and status. Homosexual (N=591 men; M age=28.87 years, SD=10.21; N=249 women; M age=33.36 years, SD=13.12) and heterosexual participants (N=346 men; M age=39.74 years, SD=14.26; N=400 women; M age=35.93 years, SD=13.72) rated the importance of attractiveness and social status of potential partners and then, in a vignette test, expressed their desire to date hypothetical potential partners based on photographs that varied in attractiveness and status-related profiles. With ratings, heterosexual men valued attractiveness the most, followed by homosexual men, heterosexual women, and homosexual women. Heterosexual women rated social status as most important. When status profiles were manipulated and accompanied with photographs of faces, the pattern of differences between homosexuals and heterosexuals supported the self-reported results. Overall, homosexual men and women have similar mate preferences to heterosexual men and women by showing more dating desire for attractive and high social status persons. Compared to attractiveness, status played a smaller role in dating desire.

  5. Homosexual Behavior in Female Mountain Gorillas: Reflection of Dominance, Affiliation, Reconciliation or Arousal?

    Science.gov (United States)

    Grueter, Cyril C; Stoinski, Tara S

    2016-01-01

    Humans are unique among primates for not only engaging in same-sex sexual acts, but also forming homosexual pair bonds. To shed light on the evolutionary origins of homosexuality, data on the occurrence and contexts of same-sex behavior from nonhuman primates may be of particular significance. Homosexual behavior involving females is poorly researched in most primate taxa, exceptions being Japanese macaques, rhesus macaques, Hanuman langurs and bonobos. We present data on homosexual behavior in female mountain gorillas in the Virunga Volcanoes (Rwanda) and test four functional hypotheses, namely reconciliation, affiliation, dominance expression and sexual arousal. Homosexual interactions between females involved both ventro-dorsal and ventro-ventral copulations accompanied by vocalizations and courtship displays. The only sociosexual hypothesis that received partial empirical support is the social status hypothesis, i.e., that mounting reaffirms the dominance hierarchy. There is also some limited evidence that same-sex behavior reflects an overall state of arousal or is triggered via a 'pornographic' effect. An adaptive function of female homosexual behavior is not readily apparent, and we tentatively conclude (until a more rigorous test becomes available) that it may simply be related to sexual gratification or that it is an evolutionary by-product of an adaptation.

  6. Alcohol consumption and high risk sexual behaviour among female ...

    African Journals Online (AJOL)

    Alcohol consumption has been associated with high risk sexual behaviour among key populations such as female sex workers. We explored the drivers of alcohol consumption and its relationship to high risk sexual behaviour. Participants were drawn from a cohort of 1 027 women selected from 'hot spots' in the suburbs of ...

  7. Correlation between high-risk pregnancy and developmental delay ...

    African Journals Online (AJOL)

    Background: The future development of children is considered more than ever now due to the advances in medical knowledge and thus the increase in survival rates of high-risk infants. This study investigated the correlation between high-risk pregnancy and developmental delay in children aged 4- 60 months. Methods: ...

  8. Drug response prediction in high-risk multiple myeloma

    DEFF Research Database (Denmark)

    Vangsted, A J; Helm-Petersen, S; Cowland, J B

    2018-01-01

    from high-risk patients by GEP70 at diagnosis from Total Therapy 2 and 3A to predict the response by the DRP score of drugs used in the treatment of myeloma patients. The DRP score stratified patients further. High-risk myeloma with a predicted sensitivity to melphalan by the DRP score had a prolonged...

  9. Elevated level of serum triglyceride among high risk stress bank ...

    African Journals Online (AJOL)

    The objective of this study was to estimate lipid profile among high risk stress bank employees' correlated with heart disorders in Riyadh, Saudi Arabia. A total of 129 patients with high risk stress employees were involved in this study, which were divided into 69 males and 60 females between the age of 25 to 55 years.

  10. Potent neutralizing serum immunoglobulin A (IgA) in human immunodeficiency virus type 2-exposed IgG-seronegative individuals

    DEFF Research Database (Denmark)

    Lizeng, Q; Nilsson, C; Sourial, S

    2004-01-01

    Links Potent neutralizing serum immunoglobulin A (IgA) in human immunodeficiency virus type 2-exposed IgG-seronegative individuals.Lizeng Q, Nilsson C, Sourial S, Andersson S, Larsen O, Aaby P, Ehnlund M, Bjorling E. Research Center, South Hospital, Stockholm, Sweden. The mechanisms behind...... the resistance to human immunodeficiency virus type 2 (HIV-2) infection are still not fully understood. In the present study, we explored the HIV-2-specific humoral serum immunoglobulin A (IgA) immune response in HIV-2-exposed IgG-seronegative (EGSN) individuals. Serum samples from heterosexual EGSN individuals...... and their known HIV-2-infected partners, as well as controls originating from Guinea-Bissau in Africa, were studied. Antibody reactivity to native and recombinant envelope glycoproteins was investigated, and the capacity of purified serum IgA to neutralize HIV-2(SBL6669) was tested. Our results showed that 16...

  11. Adolescents' and young adults' perception of homosexuality and related factors in three Asian cities.

    Science.gov (United States)

    Feng, Yongliang; Lou, Chaohua; Gao, Ersheng; Tu, Xiaowen; Cheng, Yan; Emerson, Mark R; Zabin, Laurie S

    2012-03-01

    Adolescents' and young adults' perception of homosexuality plays an important role in the marginalization and stigmatization of the homosexual, thereby influencing his or her health. This article aims to study that perception and to examine its predictors in three Asian cities that are culturally dominated by Confucianism. From May 2006 to January 2007, a cross-sectional survey of 17,016 adolescents and young adults, aged 15-24 years old, in both urban and rural sites of three Asian cities (Hanoi in Vietnam, Shanghai in the mainland of China, and Taipei in Taiwan) was conducted through interview and computer-assisted self-interview for sensitive questions. Chi-square tests and multivariate logistic regression were performed to identify the predictors for their perception of homosexuality. The percentage of adolescents and young adults who hold a positive view of homosexuality (i.e., thought it was normal and/or acceptable) was low, especially in Hanoi and Shanghai; these figures increased from Hanoi to Shanghai to Taipei for both males and females. Overall, those factors significantly associated with adolescents' and young adults' perception of homosexuality included individuals' demographic characteristics (urban/rural, age, economic status, student status, and educational level), preferred origin of movies/videos, self-identified sexual orientation, sexual and reproductive health knowledge, family values, gender role values, and attitudes toward premarital sex. In these three Asian cities composed of populations whose views are largely influenced by Confucianism, adolescents and young adults mainly hold a negative perception of homosexuality. The most common and important predictors for a respondent's perception of homosexuality were his or her knowledge of sexual and reproductive health and how traditional his/her values may be. Greater attention needs to be paid to the popularization of knowledge about sexual and reproductive health including homosexuality

  12. Problematické životní situace osob s homosexuální orientací

    OpenAIRE

    VESELÁKOVÁ, Jesika

    2011-01-01

    Homosexuality may be encountered in all cultural and historical formations. Different cultures have different views of sexuality, its expression and forms in general. The difference of the homosexual orientation and the way this phenomenon is reflected in the society influences the life of persons with homosexual orientation. Individuals are often confronted with an inner conflict with the heterosexual majority, which may result in his existential stress. Mastering problematic situations in l...

  13. A Case of Paraneoplastic Remitting Seronegative Symmetrical Synovitis with Pitting Edema Syndrome Improved by Chemotherapy

    Directory of Open Access Journals (Sweden)

    Takahiko Sakamoto

    2017-12-01

    Full Text Available The patient was a 69-year-old male who had started experiencing acute-onset pain in both shoulder joints and edema of both hands and feet. His symptoms progressively worsened within 1 month. Laboratory data indicated elevated CRP and erythrocyte sedimentation rate despite the normal range of antinuclear antibodies and rheumatoid factor and normal organ function. Furthermore, imaging data of the hand indicated synovitis without bone erosions. Meanwhile, chest CT revealed a lung tumor, leading to a diagnosis of primary lung adenocarcinoma with EGFR mutation (cT2aN3M0, stage IIIB. Based on these findings, he was diagnosed as suffering from paraneoplastic remitting seronegative symmetrical synovitis with pitting edema (RS3PE syndrome. Thereafter, his symptoms disappeared as the tumor size was rapidly decreased by gefitinib therapy for lung adenocarcinoma. Currently, RS3PE syndrome can be classified as a vascular endothelial growth factor (VEGF-associated disorder. Given that his symptoms improved by chemotherapy, the present case further supported the possible hypothesis that paraneoplastic RS3PE syndrome might be caused by tumor-induced VEGF. Therefore, the present case suggested that the symptoms of acute-onset joint pain accompanied by pitting edema in elderly patients should be considered suspicious for a malignant tumor, thereby warranting a detailed full-body examination.

  14. The false sero-negativity of brucella standard agglutination test: Prozone phenomenon

    Directory of Open Access Journals (Sweden)

    İrfan Binici

    2011-12-01

    Full Text Available Objectives: We aimed to assess prozone phenomenon that is quite rare and causes false negativity in serological diagnosisof brucellosis with standard dilution titers.Materials and methods: In this study the tests of four cases that have false negative serological results were evaluated.Blood cultures were obtained from all cases while cerebrospinal fluid cultures were studied in the two cases. Standardagglutination test (SAT and Coombs test were performed to all patients.Results: SAT and Coombs test was negative in titers up to 1/640 in all cases. The SAT and Coombs tests in cerebrospinalfluid (CSF of the two cases with neurobrucellosis diagnosis were negative, as well. Since the clinical and laboratoryfindings suggested the brucellosis, the serums were restudied by diluting up to 1/10240 titer and we saw that the first3 cases became positive at a titer of 1/1280. The fourth case remained negative and therefore, we applied high dilutionCoombs test. This time the test gave a positive result at 1/10240 titer beginning from 1/2560 titer. B.melitensis wasisolated from two cases.Conclusion: SAT and Coombs’ test must be diluted to titers 1/2560 or more in order to exclude false sero-negativity incases with clinical and laboratory findings suggesting brucellosis. J Microbiol Infect Dis 2011; 1(3:110-113

  15. Radical prostatectomy for high-risk prostate cancer.

    Science.gov (United States)

    Yossepowitch, Ofer; Eastham, James A

    2008-06-01

    Consensus recommendations for the identification and treatment of men whose apparent organ confined prostate cancer has high risk features are lacking. Despite ongoing refinements in surgical technique and improvements in morbidity and functional outcomes, the tradition of steering high-risk patients away from radical prostatectomy (RP) remains steadfast. We performed a medical literature search in English using MEDLINE/PubMed that addressed high risk prostate cancer. We analyzed the literature with respect to the historical evolution of this concept, current risk stratification schemes and treatment guidelines and related short and long term outcomes following RP. Contemporary evidence suggest that patients classified with high-risk prostate cancer by commonly used definitions do not have a uniformly poor prognosis after RP. Many cancers categorized clinically as high risk are actually pathologically confined to the prostate, and most men with such cancers who undergo RP are alive and free of additional therapy long after surgery. RP in the high-risk setting appears to be associated with a similar morbidity as in lower-risk patients. Men with clinically localized high-risk prostate cancer should not be categorically disqualified from local definitive therapy with RP. With careful attention to surgical technique, cancer control rates should improve further, and adverse effects on quality of life after RP should continue to decrease.

  16. The Very High Risk Prostate Cancer – a Contemporary Update

    Science.gov (United States)

    Mano, Roy; Eastham, James; Yossepowitch, Ofer

    2017-01-01

    Background Treatment of high-risk prostate cancer has evolved considerably over the past two decades, yet patients with very high-risk features may still experience poor outcome despite aggressive therapy. We review the contemporary literature focusing on current definitions, role of modern imaging and treatment alternatives in very high-risk prostate cancer. Methods We searched the MEDLINE database for all clinical trials or practice guidelines published in English between 2000 – 2016 with the following search terms: ‘prostatic neoplasms’ (MeSH Terms) AND (‘high risk’ (keyword) OR ‘locally advanced’ (keyword) OR ‘node positive’ (keyword)). Abstracts pertaining to very high-risk prostate cancer were evaluated and 40 pertinent studies served as the basis for this review. Results The term ‘very’ high-risk prostate cancer remains ill defined. The EAU and NCCN guidelines provide the only available definitions, categorizing those with clinical stage T3-4 or minimal nodal involvement as very-high risk irrespective of PSA level or biopsy Gleason score. Modern imaging with mpMRI and PET-PSMA scans plays a role in pretreatment assessment. Local definitive therapy by external beam radiation combined with androgen deprivation is supported by several randomized clinical trials whereas the role of surgery in the very high-risk setting combined with adjuvant radiation/ androgen deprivation therapy is emerging. Growing evidence suggest neoadjuvant taxane based chemotherapy in the context of a multimodal approach may be beneficial. Conclusions Men with very high-risk tumors may benefit from local definitive treatment in the setting of a multimodal regimen, offering local control and possibly cure in well selected patients. Further studies are necessary to better characterize the ‘very’ high-risk category and determine the optimal therapy for the individual patient. PMID:27618950

  17. Neural circuits of disgust induced by sexual stimuli in homosexual and heterosexual men: An fMRI study

    International Nuclear Information System (INIS)

    Zhang Minming; Hu Shaohua; Xu Lijuan; Wang Qidong; Xu Xiaojun; Wei Erqing; Yan Leqin; Hu Jianbo; Wei Ning; Zhou Weihua; Huang Manli; Xu Yi

    2011-01-01

    Few studies demonstrated neural circuits related to disgust were influenced by internal sexual orientation in male. Here we used fMRI to study the neural responses to disgust in homosexual and heterosexual men to investigate that issue. Thirty-two healthy male volunteers (sixteen homosexual and sixteen heterosexual) were scanned while viewing alternating blocks of three types of erotic film: heterosexual couples (F-M), male homosexual couples (M-M), and female homosexual couples (F-F) engaged in sexual activity. All the participants rated their level of disgust and sexual arousal as well. The F-F and M-M stimuli induced disgust in homosexual and heterosexual men, respectively. The common activations related to disgusting stimuli included: bilateral frontal gyrus and occipital gyrus, right middle temporal gyrus, left superior temporal gyrus, right cerebellum, and right thalamus. Homosexual men had greater neural responses in the left medial frontal gyrus than did heterosexual men to the sexual disgusting stimuli; in contrast, heterosexual men showed significantly greater activation than homosexual men in the left cuneus. ROI analysis showed that negative correlation were found between the magnitude of MRI signals in the left medial frontal gyrus and scores of disgust in homosexual subjects (p < 0.05). This study indicated that there were regions in common as well as regions specific for each type of erotic stimuli during disgust of homosexual and heterosexual men.

  18. Neural circuits of disgust induced by sexual stimuli in homosexual and heterosexual men: An fMRI study

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Minming [Department of Radiology, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou (China); Hu Shaohua [Department of Mental Health, First Affiliated Hospital, College of Medicine, Zhejiang University, 79 Qing Chun Road, Hangzhou, Zhejiang Province 310003 (China); Xu Lijuan [National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing (China); Wang Qidong [Department of Radiology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou (China); Xu Xiaojun [Department of Radiology, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou (China); Wei Erqing [College of Pharmacology, Zhejiang University (China); Yan Leqin [MD Anderson Cancer Center, Virginia Harris Cockrell Cancer Research Center, University of Texas, Austin (United States); Hu Jianbo; Wei Ning; Zhou Weihua; Huang Manli [Department of Mental Health, First Affiliated Hospital, College of Medicine, Zhejiang University, 79 Qing Chun Road, Hangzhou, Zhejiang Province 310003 (China); Xu Yi, E-mail: xuyi61@yahoo.com.cn [Department of Mental Health, First Affiliated Hospital, College of Medicine, Zhejiang University, 79 Qing Chun Road, Hangzhou, Zhejiang Province 310003 (China)

    2011-11-15

    Few studies demonstrated neural circuits related to disgust were influenced by internal sexual orientation in male. Here we used fMRI to study the neural responses to disgust in homosexual and heterosexual men to investigate that issue. Thirty-two healthy male volunteers (sixteen homosexual and sixteen heterosexual) were scanned while viewing alternating blocks of three types of erotic film: heterosexual couples (F-M), male homosexual couples (M-M), and female homosexual couples (F-F) engaged in sexual activity. All the participants rated their level of disgust and sexual arousal as well. The F-F and M-M stimuli induced disgust in homosexual and heterosexual men, respectively. The common activations related to disgusting stimuli included: bilateral frontal gyrus and occipital gyrus, right middle temporal gyrus, left superior temporal gyrus, right cerebellum, and right thalamus. Homosexual men had greater neural responses in the left medial frontal gyrus than did heterosexual men to the sexual disgusting stimuli; in contrast, heterosexual men showed significantly greater activation than homosexual men in the left cuneus. ROI analysis showed that negative correlation were found between the magnitude of MRI signals in the left medial frontal gyrus and scores of disgust in homosexual subjects (p < 0.05). This study indicated that there were regions in common as well as regions specific for each type of erotic stimuli during disgust of homosexual and heterosexual men.

  19. Cutaneous Microenvironment of Human Immunodeficiency Virus (HIV)-Seropositive and HIV-Seronegative Individuals, with Special Reference to Staphylococcus aureus Colonization

    OpenAIRE

    Shapiro, Michael; Smith, Kathleen J.; James, William D.; Giblin, Walter J.; Margolis, David J.; Foglia, Arlene N.; McGinley, Kenneth; Leyden, James J.

    2000-01-01

    A cross-sectional quantitative study of cutaneous bacterial and yeast flora at seven body sites in 99 human immunodeficiency virus-seropositive and 50 seronegative military personnel was performed. Statistically significant differences in carriage rates were only observed for Staphylococcus aureus on the foreheads of seropositive individuals. Seronegative individuals demonstrated staphylococcal carriage rates 1.3 to 2 times as great as those of historical controls (defined as healthy individu...

  20. Fag Men: Mad Men, Homosexuality and Televisual Style

    Directory of Open Access Journals (Sweden)

    Lee Wallace

    2012-09-01

    Full Text Available Among the many retro-fittings achieved by Mad Men—Matthew Weinerʼs still unfurling television series set in the advertising world of the early 1960s—is the representation of the homosexual closet as a thing of the past. This essay approaches Mad Men’s account of the homophobic past in order to think about sexuality and televisual style. A landmark programme coterminous with American television transferring from analogue to digital signal, Mad Men allegorizes another moment in television history when the medium was defined not by convergence and time-shifting but by liveness, scheduling flow, mass-market demographics and synchronous viewing. Though it confines its gay content to minor characters and narrative arcs that phase in and out in relation to open-ended long-form needs, the programme’s representation of homophobia as a thing of the past provides a useful lens on the complex temporal co-ordinates of contemporary television.

  1. Revista Somos y la militancia homosexual en los '70

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    Gastón Klocker

    2018-01-01

    Full Text Available Dentro del contexto de turbulencias políticas, sociales y culturales que caracterizaron a las décadas de 1960 y 1970 a nivel mundial, continental, y más específicamente, en Argentina; surge la revista Somos, órgano de prensa y difusión del Frente de Liberación Homosexual (FLH. Este acercamiento investigativo buscará reseñar la publicación con el objetivo de establecerla como visor central de aspectos que rodearon al FLH. Para eso partiremos de una revisión histórica de antecedentes, documentos y manifiestos, vertientes ideológicas, estructura organizacional y su diálogo con Organizaciones Armadas y células de la Triple A alineadas al Nacionalismo Católico en la voz de la revista El Caudillo. El corpus a trabajar es una plataforma periodística de ocho ediciones bimensuales que van de diciembre de 1973 a enero de 1976.

  2. Performative family: homosexuality, marriage and intergenerational dynamics in China.

    Science.gov (United States)

    Choi, Susanne Yp; Luo, Ming

    2016-06-01

    Using in-depth interview data on nominal marriages - legal marriages between a gay man and a lesbian to give the appearance of heterosexuality - this paper develops the concept of performative family to explain the processes through which parents and their adult children negotiate and resolve disagreements in relation to marriage decisions in post-socialist China. We identify three mechanisms - network pressure, a revised discourse of filial piety and resource leverage - through which parents influence their gay offspring's decision to turn to nominal marriage. We also delineate six strategies, namely minimizing network participation, changing expectations, making partial concessions, drawing the line, delaying decisions and ending the marriage, by which gay people in nominal marriages attempt to meet parental expectations while simultaneously retaining a degree of autonomy. Through these interactions, we argue that Chinese parents and their gay adult children implicitly and explicitly collaborate to perform family, emphasizing the importance of formally meeting society's expectations about marriage rather than substantively yielding to its demands. We also argue that the performative family is a pragmatic response to the tension between the persistent centrality of family and marriage and the rising tide of individualism in post-socialist China. We believe that our findings highlight the specific predicament of homosexual people. They also shed light on the more general dynamics of intergenerational negotiation because there is evidence that the mechanisms used by parents to exert influence may well be similar between gay and non-gay people. © London School of Economics and Political Science 2016.

  3. Experiences of homosexual patients’ access to primary health care services in Umlazi, KwaZulu-Natal

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    Nokulunga H. Cele

    2015-09-01

    Full Text Available Background: Homosexual patients are affected by social factors in their environment, and as a result may not have easy access to existing health care services. Prejudice against homosexuality and homosexual patients remains a barrier to them seeking appropriate healthcare. The concern is that lesbians and gays might delay or avoid seeking health care when they need it because of past discrimination or perceived homophobia within the health care thereby putting their health at risk. Aim of the study: The aim of the study was to explore and describe the experiences of homosexual patients utilising primary health care (PHC services in Umlazi in the province ofKwaZulu-Natal (KZN. Method: A qualitative, exploratory, descriptive study was conducted which was contextual innature. Semi-structured interviews were conducted with 12 participants. The findings of this study were analysed using content analysis. Results: Two major themes emerged from the data analysis, namely, prejudice against homosexual patients by health care providers and other patients at the primary health care facilities, and, homophobic behaviour from primary health care personnel. Conclusion: Participants experienced prejudice and homophobic behaviour in the course of utilising PHC clinics in Umlazi, which created a barrier to their utilisation of health services located there. Nursing education institutions, in collaboration with the National Department of Health, should introduce homosexuality and anti-homophobia education programmes during the pre-service and in-service education period. Such programmes will help to familiarise health care providers with the health care needs of homosexual patients and may decrease homophobic attitudes.

  4. O debate sobre a homossexualidade mediado por representações sociais: perspectivas homossexuais e heterossexuais The debate on homosexuality mediated by social representations: homosexual and heterosexual perspectives

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    Anderson Scardua

    2006-01-01

    Full Text Available O objetivo deste trabalho foi estudar as representações sociais da homossexualidade entre estudantes universitários, segundo orientação sexual e sexo. Foram aplicadas uma questão de associação livre sobre a palavra homossexualidade e outra sobre as possíveis causas da mesma, sendo os dados analisados segundo os princípios da análise de conteúdo. Houve diferenças significativas entre os grupos, possibilitando-nos encontrar diferentes maneiras de se compreender/lidar com a homossexualidade e enfrentar preconceitos/discriminações. Os homens homossexuais, procuraram justificar/legitimar publicamente (direitos, liberdade a homossexualidade com o argumento/representação de que ela é incontrolável/natural, enquanto as mulheres homossexuais preferiram construir e aperfeiçoar contratos de interação no plano interpessoal (família, namoro para obter reconhecimento social. Já os homens e mulheres heterossexuais, referindo-se muito à normatização e outros conteúdos que reforçam as convenções sociais indicaram menos possibilidade de reconhecimento da homossexualidade.The objective of this work was to study the social representations of homosexuality among college students, according to sexual orientation and sex. One free association question about the word homosexuality and another about is possible causes were answered. The data was analyzed according to the principles of content analysis. There were significant differences among the groups, allowing us to find out different ways of understanding/dealing with homosexuality and facing prejudice/discrimination. The homosexual men publicly justified/legitimated (rights, freedom homosexuality with the argument/representation that it is uncontrollable/natural, while the homosexual women preferred to build and improve interaction agreements on the interpersonal level (family, love affair to obtain social recognition. Yet the heterosexual men and women, with many references to

  5. Socialization Patterns and Their Association with Unprotected Anal Intercourse, HIV, and Syphilis Among High-Risk Men Who Have Sex with Men and Transgender Women in Peru

    Science.gov (United States)

    Verre, MC; Peinado, J; Segura, ER; Clark, JC; Gonzales, P; Benites, C; Cabello, R; Sanchez, J; Lama, JR

    2014-01-01

    The association of socialization patterns with unprotected anal intercourse (UAI) and HIV/STI prevalence remains underexplored in men who have sex with men (MSM) and transgender women (TW) in developing country settings. We evaluated the correlation of UAI, HIV, and syphilis with MSM/TW venue attendance and social network size among high-risk MSM and TW in Peru according to self-reported sexual identity. Frequency of venue attendance and MSM/TW social network size were lowest among heterosexual MSM and highest among TW respondents. Attendance (frequent or occasional) at MSM/TW venues was associated with increased odds of insertive UAI among heterosexual participants. Frequent venue attendance was associated with increased odds of receptive UAI among gay/homosexual, bisexual, and TW participants. Further investigation of the differing socialization patterns and associations with HIV/STI transmission within subgroups of Peruvian MSM and TW will enable more effective prevention interventions for these populations. PMID:24788782

  6. Sensation seeking in males involved in recreational high risk sports

    OpenAIRE

    M Guszkowska; A Bołdak

    2010-01-01

    The study examined sensation seeking intensity level in males involved in recreational high risk sports and investigated whether its level depends on type of sport practised. Additionally, in case of parachutists, sport experience of study participants were scrutinised with regard to its possible impact on the level of sensation seeking.The research involved 217 males aged 17 to 45, practising recreational high risk sports, namely: parachuting (n=98); wakeboarding (n=30); snowboarding (n=30);...

  7. Adolescents’ and Young Adults’ Perception of Homosexuality and Related Factors in Three Asian Cities

    Science.gov (United States)

    Feng, Yongliang; Lou, Chaohua; Gao, Ersheng; Tu, Xiaowen; Cheng, Yan; Emerson, Mark R.; Zabin, Laurie S.

    2014-01-01

    Purpose Adolescents’ and young adults’ perception of homosexuality plays an important role in the marginalization and stigmatization of the homosexual, thereby influencing his or her health. This article aims to study that perception and to examine its predictors in three Asian cities that are culturally dominated by Confucianism. Methods From May 2006 to January 2007, a cross-sectional survey of 17,016 adolescents and young adults, aged 15–24 years old, in both urban and rural sites of three Asian cities (Hanoi in Vietnam, Shanghai in the mainland of China, and Taipei in Taiwan) was conducted through interview and computer-assisted self-interview for sensitive questions. Chi-square tests and multivariate logistic regression were performed to identify the predictors for their perception of homosexuality. Results The percentage of adolescents and young adults who hold a positive view of homosexuality (i.e., thought it was normal and/or acceptable) was low, especially in Hanoi and Shanghai; these figures increased from Hanoi to Shanghai to Taipei for both males and females. Overall, those factors significantly associated with adolescents’ and young adults’ perception of homosexuality included individuals’ demographic characteristics (urban/rural, age, economic status, student status, and educational level), preferred origin of movies/videos, self-identified sexual orientation, sexual and reproductive health knowledge, family values, gender role values, and attitudes toward premarital sex. Conclusions In these three Asian cities composed of populations whose views are largely influenced by Confucianism, adolescents and young adults mainly hold a negative perception of homosexuality. The most common and important predictors for a respondent's perception of homosexuality were his or her knowledge of sexual and reproductive health and how traditional his/her values may be. Greater attention needs to be paid to the popularization of knowledge about sexual and

  8. A social work study high-risk behavior among teenagers

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    Mohammad Reza Iravani

    2012-01-01

    Full Text Available Teenagers are believed the people who are supposed to build the world's future. High-risk behaviors such as addiction to drugs, smoking cigarettes, sex, etc. could significantly hurts teenagers and there must be some supporting programs to reduce these issues as much as possible. This paper performs an empirical investigation to study the different factors influencing high- risk behavior among teenagers who live in a city of Esfahan, Iran. The proposed study designs a questionnaire and distribute between two groups of female and male teenagers. The results indicate that while there is a meaningful relationship between high-risk behaviors and average high school marks among male students there is no meaningful relationship between high-risk behaviors and high school grades among female students. The results also indicate that there is a meaningful difference between gender and high-risk behavior. The season of birth for female and male students is another important factor for having high-risk behaviors. While the order of birth plays an important role among male students, the order of birth is not an important factor among female teenagers. Finally, the results indicate that teenagers' parental financial affordability plays a vital role on both female and male teenagers.

  9. Place matters: Contextualizing the roles of religion and race for understanding Americans' attitudes about homosexuality.

    Science.gov (United States)

    Adamczyk, Amy; Boyd, Katharine A; Hayes, Brittany E

    2016-05-01

    As laws and policies related to homosexuality have evolved, Americans' attitudes have also changed. Race and religion have been established as important indicators of feelings about homosexuality. However, researchers have given almost no attention to how county characteristics shape Americans' attitudes. Using Hierarchical Linear Modeling techniques, we examine how personal characteristics and the religious and racial context of a county shape feelings about homosexuality drawing on data from the American National Election Survey and information about where respondents reside. We find that African Americans initially appear less tolerant than other racial groups, until we account for the geographical distribution of attitudes across the nation. Additionally, once we consider religious involvement, strength of belief, and religious affiliation African Americans appear to have warmer feelings about homosexuality than whites. Drawing on the moral communities' hypothesis, we also find that the strength of religiosity amongst county residents heightens the influence of personal religious beliefs on disapproving attitudes. There is also a direct effect of the proportion conservative Protestant, whereby people of all faiths have cooler attitudes towards homosexual individuals when they reside in a county with a higher proportion of conservative Protestants. Finally, we do not find any evidence for an African American cultural influence on attitudes. Published by Elsevier Inc.

  10. Chinese Culture, Homosexuality Stigma, Social Support and Condom Use: A Path Analytic Model.

    Science.gov (United States)

    Liu, Hongjie; Feng, Tiejian; Ha, Toan; Liu, Hui; Cai, Yumao; Liu, Xiaoli; Li, Jian

    2011-01-01

    PURPOSE: The objective of this study was to examine the interrelationships among individualism, collectivism, homosexuality-related stigma, social support, and condom use among Chinese homosexual men. METHODS: A cross-sectional study using the respondent-driven sampling approach was conducted among 351 participants in Shenzhen, China. Path analytic modeling was used to analyze the interrelationships. RESULTS: The results of path analytic modeling document the following statistically significant associations with regard to homosexuality: (1) higher levels of vertical collectivism were associated with higher levels of public stigma [β (standardized coefficient) = 0.12] and self stigma (β = 0.12); (2) higher levels of vertical individualism were associated with higher levels self stigma (β = 0.18); (3) higher levels of horizontal individualism were associated with higher levels of public stigma (β = 0.12); (4) higher levels of self stigma were associated with higher levels of social support from sexual partners (β = 0.12); and (5) lower levels of public stigma were associated with consistent condom use (β = -0.19). CONCLUSIONS: The findings enhance our understanding of how individualist and collectivist cultures influence the development of homosexuality-related stigma, which in turn may affect individuals' decisions to engage in HIV-protective practices and seek social support. Accordingly, the development of HIV interventions for homosexual men in China should take the characteristics of Chinese culture into consideration.

  11. The burden of poofs: criminal pathology, clinical scrutiny, and homosexual etiology in queer cinema.

    Science.gov (United States)

    Wahlert, Lance

    2013-06-01

    Given the resurgence of scientific studies on the etiology of homosexuality in the wake of the AIDS epidemic, this article considers the effects these studies had on contemporaneous queer filmmakers. By using the subject of criminality as a way to talk about homosexual causality, queer films of the 1990s illustrate that contemporary scientific studies on homosexuality were historically and politically situated in relation to cultural anxieties about other forms of deviance. This article focuses on films that dissect the hetero-normative tendency to amalgamate forms of deviance in order to distinguish between the diseased and the healthy. Such products of New Queer Cinema highlight this amalgamation of criminality and homosexuality in order to challenge demands by the LGBT community of the 1980s and 1990s for "more positive images" in film. This article argues that queer filmmakers have manipulated the image of the queer criminal to usurp the medical tendency to biologize and pathologize the notion of queer transgression. In such a way, queer films that enthusiastically dramatize the queer outlaw perpetuate myths about homosexuality in order to dissect and discredit them.

  12. Childhood family correlates of heterosexual and homosexual marriages: a national cohort study of two million Danes.

    Science.gov (United States)

    Frisch, Morten; Hviid, Anders

    2006-10-01

    Children who experience parental divorce are less likely to marry heterosexually than those growing up in intact families; however, little is known about other childhood factors affecting marital choices. We studied childhood correlates of first marriages (heterosexual since 1970, homosexual since 1989) in a national cohort of 2 million 18-49 year-old Danes. In multivariate analyses, persons born in the capital area were significantly less likely to marry heterosexually, but more likely to marry homosexually, than their rural-born peers. Heterosexual marriage was significantly linked to having young parents, small age differences between parents, stable parental relationships, large sibships, and late birth order. For men, homosexual marriage was associated with having older mothers, divorced parents, absent fathers, and being the youngest child. For women, maternal death during adolescence and being the only or youngest child or the only girl in the family increased the likelihood of homosexual marriage. Our study provides population-based, prospective evidence that childhood family experiences are important determinants of heterosexual and homosexual marriage decisions in adulthood.

  13. Chinese Culture, Homosexuality Stigma, Social Support and Condom Use: A Path Analytic Model

    Science.gov (United States)

    Liu, Hongjie; Feng, Tiejian; Ha, Toan; Liu, Hui; Cai, Yumao; Liu, Xiaoli; Li, Jian

    2011-01-01

    Purpose The objective of this study was to examine the interrelationships among individualism, collectivism, homosexuality-related stigma, social support, and condom use among Chinese homosexual men. Methods A cross-sectional study using the respondent-driven sampling approach was conducted among 351 participants in Shenzhen, China. Path analytic modeling was used to analyze the interrelationships. Results The results of path analytic modeling document the following statistically significant associations with regard to homosexuality: (1) higher levels of vertical collectivism were associated with higher levels of public stigma [β (standardized coefficient) = 0.12] and self stigma (β = 0.12); (2) higher levels of vertical individualism were associated with higher levels self stigma (β = 0.18); (3) higher levels of horizontal individualism were associated with higher levels of public stigma (β = 0.12); (4) higher levels of self stigma were associated with higher levels of social support from sexual partners (β = 0.12); and (5) lower levels of public stigma were associated with consistent condom use (β = −0.19). Conclusions The findings enhance our understanding of how individualist and collectivist cultures influence the development of homosexuality-related stigma, which in turn may affect individuals’ decisions to engage in HIV-protective practices and seek social support. Accordingly, the development of HIV interventions for homosexual men in China should take the characteristics of Chinese culture into consideration. PMID:21731850

  14. Immunological and hematological reference intervals among HIV-seronegative pregnant women in northwest Ethiopia

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    Genetu M

    2017-03-01

    Full Text Available Meaza Genetu,1 Debasu Damtie,1 Meseret Workineh,1 Biniam Mathewos Tebeje,1,2 Bamlaku Enawgaw,3 Tekalign Deressa1 1Department of Immunology and Molecular Biology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia; 2Molecular Parasitology Laboratory, Queensland Institute of Medical Research, Brisbane, Australia; 3Department of Hematology and Immunohematology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia Background: Pregnancy is a state characterized by profound physiological hematological changes. However, hematological reference intervals being used in clinical practice in Ethiopia are derived from nonlocal general populations, despite the significant variations reported previously. The aim of this study was to determine the immunological and hematological reference intervals in healthy pregnancy among HIV-seronegative pregnant women in northwest Ethiopia.Materials and methods: A total of 200 healthy, HIV-seronegative pregnant women were enrolled from February 2015 to June 2015 in a cross-sectional study setting at Gondar University Hospital. Sociodemographic and obstetric data were collected using a structured questionnaire. Blood samples collected from each participant were used to define the immunological and hematological parameters. The mean, median, and 95% interval values were calculated for the immunological and hematological parameters. P-value <0.05 was considered statistically significant for all variables.Results: This study found that there were changes in CD4+ T-cell count, platelet count, and hematocrit (HCT values as pregnancy advances. The calculated combined reference intervals for the absolute CD4+ T-cell count and platelet count were 712.47–760.67 and 221.25–240.14, respectively. A progressive decline in the platelet count was observed as pregnancy advanced, with 95

  15. Characteristics and outcomes of cryptococcal meningitis in HIV seronegative children in Beijing, China, 2002–2013

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    Ling-yun Guo

    2016-11-01

    Full Text Available Abstract Background Data regarding HIV-seronegative pediatric patients with cryptococcal meningitis (CM have been very limited. Methods We retrospectively reviewed non-HIV-infected in patients with CM from January 2002 through December 2013 in Beijing Children’s Hospital. Records of the all patients were obtained and compared. Results The 34 children had a median age of 5.6 years. Most of the patients were male (67.6 %. Only 23.5 % of the cases had identifiable underlying diseases. The sensitivity of the CSF cryptococcal antigen, India ink smear and CSF culture in our study were 81.5, 85.3 and 82.4 %, respectively. And the sensitivity of combinations of these tests was 91.2 %. Out of the 34 patients, 16 (47.1 % had other organs involvement in addition to the brain. The main abnormal features via magnetic resonance imaging (MRI were Virchow-Robin space dilatation (44.4 %, hydrocephalus (38.9 %, gelatinous pseudocysts (33.3 %, brain atrophy (33.3 %, meningeal enhancement (27.8 % and local lesions (27.8 %. In total, 64.7 % of the patients were successfully treated at discharge, whereas treatment failed in 35.3 % of the patients. Conclusions Cryptococcal meningitis is an infrequent disease with a high fatality rate in children in China. The majority of patients were apparently healthy. Clinicians should consider cryptococcal infection as a potential pathogen of pediatric meningitis. Cryptococcal antigen, India ink smear and culture tests are recommended for diagnosis.

  16. Sexuality and partnership: Aspects of theological ethics in the field of marriage, unmarried and homosexual couples

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    Ulrich H.J. Körtner

    2008-01-01

    Full Text Available The attitudes towards sexuality in Western society are undergoing dramatic change. One of the main problems sexual ethics has to deal with today is the question whether the church should acknowledge unmarried long-term relationships. The debate about the acknowledgement of homosexuality as a form of human sexuality equal to heterosexuality is aiming towards the acknowledgement of the equal status of homosexual partnerships and heterosexual marriages as a final consequence. In addition to these issues the article also discusses the issue of the blessing of unmarried or homosexual couples. In light of such public blessings and their liturgical form, the article aims to discuss the question about the promise such blessings holds according to Christian ethics.

  17. Perceived cultural attitudes toward homosexuality and their effects on Iranian and American sexual minorities.

    Science.gov (United States)

    Mireshghi, Sholeh I; Matsumoto, David

    2008-10-01

    This study examined the relationship between three mental health constructs and perceived cultural attitudes toward homosexuality among lesbian, gay, and bisexual individuals. Specifically, differences in perceived cultural attitudes and depression, self-esteem, and perceived stress between 49 Iranians and 47 Americans were compared. It was hypothesized that (a) perceived cultural attitudes toward homosexuality would be more negative among Iranians than Americans; (b) perceived cultural attitudes would be related to depression, self-esteem, and perceived stress; and (c) that Iranian participants' scores on the depression, self-esteem, and perceived stress measures would reflect poorer mental health than that of their American counterparts. Results indicated more negative perceptions of cultural attitudes toward homosexuality among Iranians. Contrary to prediction, however, no difference was found in levels of depression, self-esteem, and perceived stress among American and Iranian participants. Findings are discussed in terms of cultural and familial differences with regard to sexual orientation disclosure.

  18. Homosexual men (and lesbian men) in a heterosexual genre: three gangster films from Hong Kong.

    Science.gov (United States)

    Grossman, A

    2000-01-01

    Of the East Asian film genres that have captured the attention of film goers internationally, it should be of little surprise that martial and heroically masculine genres have been the most popular, for violent action translates well into any language. Although it has been no secret that male martiality often leaks into homoerotic desire (on the part of the audience, too), three Hong Kong films from 1998 have finally explicated the generic homosexuality that the action genre has been (defensively) ashamed to admit all along. However, rather than posit this textual homosexuality as transgressive, the generic forces under which these films operate rewrite their homosexualities, both gay and lesbian, into generic modes fashioned around regressive oppositions of gender, and not progressive liberations of sexuality.

  19. "It is what it is": masculinity, homosexuality, and inclusive discourse in mixed martial arts.

    Science.gov (United States)

    Channon, Alex; Matthews, Christopher R

    2015-01-01

    In this article we make use of inclusive masculinity theory to explore online media representations of male homosexuality and masculinity within the increasingly popular combat sport of mixed martial arts (MMA). Adopting a case-study approach, we discuss narratives constructed around one aspirational male MMA fighter, Dakota Cochrane, whose history of having participated in gay pornography became a major talking point on a number of MMA discussion/community Web sites during early 2012. While these narratives attempted to discursively rescue Cochrane's supposedly threatened masculinity, highlighting both his "true" heterosexuality and his prodigious fighting abilities, they also simultaneously celebrated the acceptance of homosexual men within the sport that Cochrane's case implied. Thus, we suggest that these media representations of homosexuality and masculinity within MMA are indicative of declining cultural homophobia and homohysteria and an inclusive vision of masculinity, as previously described by proponents of inclusive masculinity theory.

  20. Homophobia as a barrier to comprehensive media coverage of the Ugandan anti-homosexual bill.

    Science.gov (United States)

    Strand, Cecilia

    2012-01-01

    The Ugandan Anti-Homosexuality Bill of October 2009 caused an international outcry and sparked intense debate in the local media. This article explores to what degree a discriminatory social environment manifests itself in the Ugandan print media and discusses the potential implications for media's coverage of contentious policy options such as the Anti-Homosexuality Bill. A content analysis of 115 items from two daily newspapers (the government-owned New Vision and the privately owned the Daily Monitor, between October and December 2009) indicates the existence of two separate house styles; this is in spite of the fact that both newspapers reproduce the surrounding society's homophobia, albeit with different frequency. Unlike the New Vision, the Daily Monitor includes coverage on homophobia and discrimination, as well as provides space for criticism of the Bill. By acknowledging discrimination and its negative impact, the newspaper de-legitimizes homophobia and problematizes the proposed Anti-homosexuality Bill for their readers.

  1. High prevalence of Epstein-Barr virus type 2 among homosexual men is caused by sexual transmission

    NARCIS (Netherlands)

    van Baarle, D.; Hovenkamp, E.; Dukers, N. H.; Renwick, N.; Kersten, M. J.; Goudsmit, J.; Coutinho, R. A.; Miedema, F.; van Oers, M. H.

    2000-01-01

    To investigate whether Epstein-Barr virus (EBV) type 2 infection is highly prevalent among homosexual men, the prevalence of EBV type 2 was studied among homosexual and heterosexual white men who were at high and low risk for sexually transmitted diseases; these data were correlated with sexual

  2. Neural circuits of disgust induced by sexual stimuli in homosexual and heterosexual men: an fMRI study.

    Science.gov (United States)

    Zhang, Minming; Hu, Shaohua; Xu, Lijuan; Wang, Qidong; Xu, Xiaojun; Wei, Erqing; Yan, Leqin; Hu, Jianbo; Wei, Ning; Zhou, Weihua; Huang, Manli; Xu, Yi

    2011-11-01

    Few studies demonstrated neural circuits related to disgust were influenced by internal sexual orientation in male. Here we used fMRI to study the neural responses to disgust in homosexual and heterosexual men to investigate that issue. Thirty-two healthy male volunteers (sixteen homosexual and sixteen heterosexual) were scanned while viewing alternating blocks of three types of erotic film: heterosexual couples (F-M), male homosexual couples (M-M), and female homosexual couples (F-F) engaged in sexual activity. All the participants rated their level of disgust and sexual arousal as well. The F-F and M-M stimuli induced disgust in homosexual and heterosexual men, respectively. The common activations related to disgusting stimuli included: bilateral frontal gyrus and occipital gyrus, right middle temporal gyrus, left superior temporal gyrus, right cerebellum, and right thalamus. Homosexual men had greater neural responses in the left medial frontal gyrus than did heterosexual men to the sexual disgusting stimuli; in contrast, heterosexual men showed significantly greater activation than homosexual men in the left cuneus. ROI analysis showed that negative correlation were found between the magnitude of MRI signals in the left medial frontal gyrus and scores of disgust in homosexual subjects (pmen. Crown Copyright © 2010. Published by Elsevier Ireland Ltd. All rights reserved.

  3. HPV knowledge, burden and genital wart location among heterosexually identified versus homosexually identified men who have sex with men in Lima, Peru: cross-sectional results from a cohort study.

    Science.gov (United States)

    Galea, Jerome T; León, Segundo R; Peinado, Jesús; Calvo, Gino; Zamora, Jonathan; Sánchez, Hugo; Brown, Brandon J

    2017-10-24

    The relationship between sexual practices, identity and role among Latino men who have sex with men (MSM) and HIV risk is the subject of ongoing investigation but less is known about how these aspects of sexuality relate to human papilloma-virus (HPV), an independent risk factor for HIV. This observational study investigated the relationship between HPV and sexual practices, identity and role as well as other sexually transmitted infection (STI)/HIV risk factors among HIV-negative heterosexually and homosexually identified Peruvian MSM. Community-based clinic for MSM in Lima, Peru. 756 subjects were screened based on inclusion criteria of: born anatomically male; age ≥18 years; had any anal intercourse with a man during the previous 12 months; residing in metropolitan Lima; HIV negative; willing to commit to twice-yearly clinic visits for 24 months; had not participated in an HIV or HPV vaccine study. 600/756 participants met the inclusion criteria and were enrolled, of whom 48% (284) identified as homosexual and 10% (57) as heterosexual, the basis of the analyses performed. Compared with homosexually identified MSM, heterosexually identified MSM had completed fewer years of formal education and were less likely to have: anogenital HPV or visible anal warts; given oral sex to a man; or used a condom with their most recent female sexual partner (all p<0.05). Conversely, heterosexually identified MSM were more likely to have: visible penile warts; used a condom during last anal intercourse; smoked cigarettes; had transactional sex; and used drugs during sex in the previous month (all p<0.01). There was no difference found between heterosexually and homosexually identified MSM by syphilis or high-risk HPV prevalence. HPV burden, wart type (penile vs anal) and select HIV/STI risk behaviours differed between heterosexually and homosexually identified Peruvian MSM. Understanding the implications of these differences can lead to tailored HIV/STI prevention interventions

  4. Brachytherapy boost and cancer-specific mortality in favorable high-risk versus other high-risk prostate cancer

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    Vinayak Muralidhar

    2016-02-01

    Full Text Available Purpose : Recent retrospective data suggest that brachytherapy (BT boost may confer a cancer-specific survival benefit in radiation-managed high-risk prostate cancer. We sought to determine whether this survival benefit would extend to the recently defined favorable high-risk subgroup of prostate cancer patients (T1c, Gleason 4 + 4 = 8, PSA 20 ng/ml. Material and methods: We identified 45,078 patients in the Surveillance, Epidemiology, and End Results database with cT1c-T3aN0M0 intermediate- to high-risk prostate cancer diagnosed 2004-2011 treated with external beam radiation therapy (EBRT only or EBRT plus BT. We used multivariable competing risks regression to determine differences in the rate of prostate cancer-specific mortality (PCSM after EBRT + BT or EBRT alone in patients with intermediate-risk, favorable high-risk, or other high-risk disease after adjusting for demographic and clinical factors. Results : EBRT + BT was not associated with an improvement in 5-year PCSM compared to EBRT alone among patients with favorable high-risk disease (1.6% vs. 1.8%; adjusted hazard ratio [AHR]: 0.56; 95% confidence interval [CI]: 0.21-1.52, p = 0.258, and intermediate-risk disease (0.8% vs. 1.0%, AHR: 0.83, 95% CI: 0.59-1.16, p = 0.270. Others with high-risk disease had significantly lower 5-year PCSM when treated with EBRT + BT compared with EBRT alone (3.9% vs. 5.3%; AHR: 0.73; 95% CI: 0.55-0.95; p = 0.022. Conclusions : Brachytherapy boost is associated with a decreased rate of PCSM in some men with high-risk prostate cancer but not among patients with favorable high-risk disease. Our results suggest that the recently-defined “favorable high-risk” category may be used to personalize therapy for men with high-risk disease.

  5. Physical activity barriers and motivators among high-risk employees.

    Science.gov (United States)

    Paguntalan, John C; Gregoski, Mathew

    2016-11-22

    Worksite wellness programs offer an ideal setting to target high-risk sedentary workers to improve health status. Lack of physical activity is associated with increased risk for coronary heart disease and mortality. Despite the risks, the number of sedentary workers is increasing. This study examined the perceived barriers and motivators for physical activity among employees at high-risk for coronary heart disease. A purposive sample of 24 high-risk workers participating in a wellness program in rural South Carolina were enrolled in the study. Qualitative data was obtained through semi-structured face-to-face interviews. Grounded theory was used to analyze qualitative data, and identify overarching themes. Physical limitations due to pain and weakness, lack of motivation, and lack of time emerged as the main barriers to physical activity. Family relationships were reported as the strongest motivator along with social support and potential health benefits. Findings highlight the unique experience of high-risk workers with physical activity. The findingsunderscore the need to design and implement effective interventions specifically designed to meet the needs of high-risk employees.

  6. Pastoral counselling of persons with homosexual tendencies in a heterosexual marriage / by Louis Antonie Gerber

    OpenAIRE

    Gerber, Louis Antonie

    2007-01-01

    The occurrence of marriages failing as a result of one member of the couple having a homosexual relationship has increased since the rewriting of the law on human rights. This resulted in a heightened need for pastoral care of members of the family that were affected by this tendency. Of cardinal importance to this study and in light of the constant debate about homosexuality in the church, a Scriptural foundation is found in the handling in cases of marriage breaking up as a resu...

  7. Recovering What Was Forgotten: Sexuality and Radical Politics in the Homosexual Liberation Movement in Colombia

    Directory of Open Access Journals (Sweden)

    José Fernando Serrano Amaya

    2012-12-01

    Full Text Available What was the meaning of “liberation” in the Homosexual Liberation Movement that emerged in Colombia at the end of the 1970s? El Otro, a homosexual magazine published at that time, is analyzed as a space where a particular discourse about sexuality took form based on the publication’s radical politics. In this discourse, the relationship between sexuality and liberation was understood as revolution, pragmatics, pedagogy and bond, however it became impossible to continue these countercultural liberation politics as rights discourses came to dominate the gay and lesbian movements in 1980s.

  8. The Influence of Pastors' Ideologies of Homosexuality on HIV Prevention in the Black Church.

    Science.gov (United States)

    Quinn, Katherine; Dickson-Gomez, Julia; Young, Staci

    2016-10-01

    Young, Black men who have sex with men (YBMSM) are disproportionately affected by HIV, and Black Churches may be a source of stigma which can exacerbate HIV risk and contribute to negative health and psychosocial outcomes. Findings from this study are based on 21 semi-structured interviews with pastors and ethnographic observation in six Black Churches. Interview transcripts and field notes were analyzed in MAXQDA using thematic content analysis. Although pastors espoused messages of love and acceptance, they overwhelmingly believed homosexuality was a sin and had difficulty accepting YBMSM into their churches. The tension around homosexuality limited pastors' involvement in HIV prevention efforts, although there still may be opportunities for some churches.

  9. Regression models for interval censored survival data: Application to HIV infection in Danish homosexual men

    DEFF Research Database (Denmark)

    Carstensen, Bendix

    1996-01-01

    This paper shows how to fit excess and relative risk regression models to interval censored survival data, and how to implement the models in standard statistical software. The methods developed are used for the analysis of HIV infection rates in a cohort of Danish homosexual men.......This paper shows how to fit excess and relative risk regression models to interval censored survival data, and how to implement the models in standard statistical software. The methods developed are used for the analysis of HIV infection rates in a cohort of Danish homosexual men....

  10. Homosexual, gay, and lesbian: defining the words and sampling the populations.

    Science.gov (United States)

    Donovan, J M

    1992-01-01

    The lack of both specificity and consensus about definitions for homosexual, homosexuality, gay, and lesbian are first shown to confound comparative research and cumulative understanding because criteria for inclusion within the subject populations are often not consistent. The Description section examines sociolinguistic variables which determine patterns of preferred choice of terminology, and considers how these might impact gay and lesbian studies. Attitudes and style are found to influence word choice. These results are used in the second section to devise recommended definitional limits which would satisfy both communication needs and methodological purposes, especially those of sampling.

  11. Radical prostatectomy in clinically localized high-risk prostate cancer

    DEFF Research Database (Denmark)

    Røder, Martin Andreas; Berg, Kasper Drimer; Christensen, Ib Jarle

    2013-01-01

    ) is regarded as primary therapy by others. This study examined the outcome for high-risk localized PCa patients treated with RP. Material and methods. Of 1300 patients who underwent RP, 231 were identified as high-risk. Patients were followed for biochemical recurrence (BCR) (defined as prostate-specific......Abstract Objective. The optimal therapeutic strategy for high-risk localized prostate cancer (PCa) is controversial. Supported by randomized trials, the combination of external beam radiation therapy (EBRT) and endocrine therapy (ET) is advocated by many, while radical prostatectomy (RP...... antigen ≥ 0.2 ng/ml), metastatic disease and survival. Excluding node-positive patients, none of the patients received adjuvant therapy before BCR was confirmed. Univariate and multivariate analysis was performed with Kaplan-Meier and Cox proportional hazard models. Results. Median follow-up was 4.4 years...

  12. The high-risk HPV infection and urinary system tumor

    Directory of Open Access Journals (Sweden)

    Yang Wenyan

    2018-04-01

    Full Text Available HPV is classified into high-risk and low-risk types depending on its probability of leading to tumorigenesis. Many studies have shown that HPV infection, especially the infection caused by the high-risk type, is always related to prostate cancer, bladder cancer, penile cancer, testicular cancer, and other urinary system tumors. However, previous studies differed in sexual openness and racial genetic susceptibility of the study object, sample size, and experimental methods. Hence, the correlation between high-risk HPV infection and urinary system tumors remains controversial. The early open reading frame of the HPV genome is composed of E1–E7, among which E6 and E7 are the key transfer proteins. The combination of these proteins with oncogene and anti-oncogene may be one of the mechanisms leading to tumorigenesis.

  13. Management of Skin Cancer in the High-Risk Patient.

    Science.gov (United States)

    Behan, James W; Sutton, Adam; Wysong, Ashley

    2016-12-01

    Skin cancer is the most common of human cancers and outnumbers all other types of cancer combined in the USA by over threefold. The majority of non-melanoma skin cancers are easily treated with surgery or locally destructive techniques performed under local anesthesia in the cost-effective outpatient setting. However, there is a subset of "high-risk" cases that prove challenging in terms of morbidity, mortality, adjuvant treatment required, as well as overall cost to the health care system. In our opinion, the term "high risk" when applied to skin cancer can mean one of three things: a high-risk tumor with aggressive histologic and/or clinical features with an elevated risk for local recurrence or regional/distant metastasis, a high-risk patient with the ongoing development of multiple skin cancers, and a high-risk patient based on immunosuppression. We have recently proposed classifying NMSC as a chronic disease in a certain subset of patients. Although no consensus definition exists for a chronic disease in medicine, there are three components that are present in most definitions: duration of at least 1 year, need for ongoing medical care, and functional impairment and/or alteration of activities of daily living (ADLs) and quality of life (QOL). Immunosuppression can refer to exogenous (organ or stem cell transplant patients,) or endogenous (HIV, leukemia, lymphoma, genodermatoses with DNA mismatch repair problems or other immunosuppression) causes. These patients are at risk for high-risk tumors and/or the development of multiple tumors.

  14. Telomerase activation by genomic rearrangements in high-risk neuroblastoma

    Science.gov (United States)

    Peifer, Martin; Hertwig, Falk; Roels, Frederik; Dreidax, Daniel; Gartlgruber, Moritz; Menon, Roopika; Krämer, Andrea; Roncaioli, Justin L.; Sand, Frederik; Heuckmann, Johannes M.; Ikram, Fakhera; Schmidt, Rene; Ackermann, Sandra; Engesser, Anne; Kahlert, Yvonne; Vogel, Wenzel; Altmüller, Janine; Nürnberg, Peter; Thierry-Mieg, Jean; Thierry-Mieg, Danielle; Mariappan, Aruljothi; Heynck, Stefanie; Mariotti, Erika; Henrich, Kai-Oliver; Glöckner, Christian; Bosco, Graziella; Leuschner, Ivo; Schweiger, Michal R.; Savelyeva, Larissa; Watkins, Simon C.; Shao, Chunxuan; Bell, Emma; Höfer, Thomas; Achter, Viktor; Lang, Ulrich; Theissen, Jessica; Volland, Ruth; Saadati, Maral; Eggert, Angelika; de Wilde, Bram; Berthold, Frank; Peng, Zhiyu; Zhao, Chen; Shi, Leming; Ortmann, Monika; Büttner, Reinhard; Perner, Sven; Hero, Barbara; Schramm, Alexander; Schulte, Johannes H.; Herrmann, Carl; O’Sullivan, Roderick J.; Westermann, Frank; Thomas, Roman K.; Fischer, Matthias

    2016-01-01

    Neuroblastoma is a malignant paediatric tumour of the sympathetic nervous system1. Roughly half of these tumours regress spontaneously or are cured by limited therapy. By contrast, high-risk neuroblastomas have an unfavourable clinical course despite intensive multimodal treatment, and their molecular basis has remained largely elusive2–4. Here we have performed whole-genome sequencing of 56 neuroblastomas (high-risk, n = 39; low-risk, n = 17) and discovered recurrent genomic rearrangements affecting a chromosomal region at 5p15.33 proximal of the telomerase reverse transcriptase gene (TERT). These rearrangements occurred only in high-risk neuroblastomas (12/39, 31%) in a mutually exclusive fashion with MYCN amplifications and ATRX mutations, which are known genetic events in this tumour type1,2,5. In an extended case series (n = 217), TERT rearrangements defined a subgroup of high-risk tumours with particularly poor outcome. Despite a large structural diversity of these rearrangements, they all induced massive transcriptional upregulation of TERT. In the remaining high-risk tumours, TERT expression was also elevated in MYCN-amplified tumours, whereas alternative lengthening of telomeres was present in neuroblastomas without TERT or MYCN alterations, suggesting that telomere lengthening represents a central mechanism defining this subtype. The 5p15.33 rearrangements juxtapose the TERT coding sequence to strong enhancer elements, resulting in massive chromatin remodelling and DNA methylation of the affected region. Supporting a functional role of TERT, neuroblastoma cell lines bearing rearrangements or amplified MYCN exhibited both upregulated TERT expression and enzymatic telomerase activity. In summary, our findings show that remodelling of the genomic context abrogates transcriptional silencing of TERT in high-risk neuroblastoma and places telomerase activation in the centre of transformation in a large fraction of these tumours. PMID:26466568

  15. Undifferentiated seronegative spondyloarthritis with inflammatory bowel disease and a family history of psoriasis. Sicca syndrome

    Directory of Open Access Journals (Sweden)

    Norma Marigliano

    2013-04-01

    Full Text Available Background: Seronegative spondyloarthritis is characterized by the presence of subcutaneous nodules, asymmetrical peripheral arthritis, sacroileitis with or without spondylitis, and rheumatoid-factor negativity. Other common clinical manifestations include oral ulcers, conjunctivitis, and cutaneous lesions such as psoriasis. Familial aggregation has also been described. According to the 1986 classification, corresponding clinical entities include ankylosing spondylitis, psoriatic arthritis, Reiter’s syndrome, arthritis associated with inflammatory bowel disease (IBD, and undifferentiated spondyloarthritis. The disease is also frequently associated with the HLA B27 antigen. From the clinical point of view, there are often incomplete forms of spondyloarthritis, such as reactive arthritis triggered by asymptomatic infections, psoriatic arthritis without psoriasis itself, initial phases of specific forms of spondyloarthritis or the phase of ankylosing spondylitis characterized by sacroiliac lesions, and all forms that remain undifferentiated for long periods of time. Moreover, there are close relations between arthropathy and IBDs, such as Crohn’s disease, ulcerative colitis, and Whipple’s syndrome. Recently, microscopic inflammatory bowel lesions and psoriatic arthritis have been described. Case report: A 30-year-old man (HLA B27-negative who had been vaccinated against TBC and HBV presented with a 6-year history of recurrent episodes of predominantly left-sided sciatica. The pain was worse at night and during rest. He was suffering from bilateral sacroileitis without spondylitis. Three to five times a day, usually after eating, he passed watery feces containing mucous and small amounts of bright red blood. Colonoscopy revealed pancolitis with histological evidence of chronic inflammation interspersed with areas of acute inflammation, edema, hyperemia, and glandular distortion. One year later, the clinical manifestations and histological

  16. Efficacy and safety of immunosuppressive therapy in the treatment of seronegative hepatitis associated aplastic anemia

    Directory of Open Access Journals (Sweden)

    Chen HF

    2014-09-01

    Full Text Available Hai-Fei Chen,* Bin-Xian Xu, Hong-Shi Shen,* Zheng-Yang Li, Ling-Juan Jin, Jie-Qing Tang, Jing Wang, Jing-Jing Zhu, Long-Mei Qin, Qing-Ya Cui, Yong-Ya Ren, Tian-Qin Wu Department of hematology, 100th hospital of People’s Liberation Army, Suzhou, Jiangsu province, The People’s Republic of China *These authors have contributed equally to this paper Objective: To investigate the clinical characteristics of seronegative hepatitis-associated aplastic anemia (AA (SNHAA and hepatitis B virus (HBV infection complicating AA (HBVAA, and thereby compare the efficacy of immunosuppressive therapy (IST.Methods: An analysis was conducted on the clinical data of ten patients with SNHAA out of 332 cases of AA from our center at AA diagnosis, and on the efficacy of IST. This was compared to 22 cases of HBVAA at AA onset as well as the associated IST outcomes.Results: Nine patients with SNHAA developed severe aplastic anemia, with a median age of 18 years. After IST, six (60% of the SNHAA patients achieved complete remission and two achieved partial remission. The patients with HBVAA had a total response rate of 82.3%. The disease recurred in two HBVAA patients. No statistically significant differences were observed in response rate, mortality, and recurrence rate between both groups. As compared with HBVAA, patients with SNHAA had a shorter interval from the acute episode of hepatitis to AA onset (4 months versus 92 months, P=0.00, a quicker response to IST (2.5 months versus 4.5 months, P=0.018, a lower proportion of bone marrow hematopoietic tissues (20.6% versus 23.6%, P=0.03, and lower white blood cell and absolute neutrophil count (0.8×109/L versus 1.23×109/L and 0.26×109/L versus 0.58×109/L, P=0.026 and P=0.0009, respectively. No significant liver damage or hepatitis B fulminant infection was observed in either group during the follow-up. Conclusion: The prevalence of SNHAA is 3.01%. SNHAA often presents as severe AA and responds to IST quickly

  17. Defective human T-cell lymphotropic virus type I (HTLV-I) provirus in seronegative tropical spastic paraparesis/HTLV-I-associated myelopathy (TSP/HAM) patients.

    Science.gov (United States)

    Ramirez, E; Fernandez, J; Cartier, L; Villota, C; Rios, M

    2003-02-01

    Infection with human T-cell lymphotropic virus type I (HTLV-I) have been associated with the development of the tropical spastic paraparesis/HTLV-I-associated myelopathy (TSP/HAM). We studied the presence of HTLV-I provirus in peripheral blood mononuclear cells (PBMC) from 72 Chilean patients with progressive spastic paraparesis by polymerase chain reaction: 32 seropositive and 40 seronegative cases. We amplified different genomic regions of HTLV-I using primers of 5' ltr, tax, env/tax, pX, pol and env genes. These genes were detected from all seropositive patients. The seronegative patients were negative with 5' ltr, pol, env, and pX primers. However, amplified product of tax and env/tax genes was detected from 16 and four seronegative patients, respectively. Three of them were positive with both genetic regions. The results of this study show that the complete HTLV-I provirus is found in 100% of seropositive cases. In seronegative cases, clinically very similar of seropositive cases, was found only tax gene in 42.5% (17/40) of patients. These results suggest the presence of a defective HTLV-I provirus in some seronegative patients with progressive spastic paraparesis, and suggest a pathogenic role of this truncate provirus for a group of TSP/HAM.

  18. Dronedarone in high-risk permanent atrial fibrillation

    DEFF Research Database (Denmark)

    Connolly, Stuart J; Camm, A John; Halperin, Jonathan L

    2011-01-01

    Dronedarone restores sinus rhythm and reduces hospitalization or death in intermittent atrial fibrillation. It also lowers heart rate and blood pressure and has antiadrenergic and potential ventricular antiarrhythmic effects. We hypothesized that dronedarone would reduce major vascular events...... in high-risk permanent atrial fibrillation....

  19. Diagnosis and Management of High Risk Group for Gastric Cancer

    Science.gov (United States)

    Yoon, Hyuk; Kim, Nayoung

    2015-01-01

    Gastric cancer is associated with high morbidity and mortality worldwide. To reduce the socioeconomic burden related to gastric cancer, it is very important to identify and manage high risk group for gastric cancer. In this review, we describe the general risk factors for gastric cancer and define high risk group for gastric cancer. We discuss strategies for the effective management of patients for the prevention and early detection of gastric cancer. Atrophic gastritis (AG) and intestinal metaplasia (IM) are the most significant risk factors for gastric cancer. Therefore, the accurate selection of individuals with AG and IM may be a key strategy for the prevention and/or early detection of gastric cancer. Although endoscopic evaluation using enhanced technologies such as narrow band imaging-magnification, the serum pepsinogen test, Helicobacter pylori serology, and trefoil factor 3 have been evaluated, a gold standard method to accurately select individuals with AG and IM has not emerged. In terms of managing patients at high risk of gastric cancer, it remains uncertain whether H. pylori eradication reverses and/or prevents the progression of AG and IM. Although endoscopic surveillance in high risk patients is expected to be beneficial, further prospective studies in large populations are needed to determine the optimal surveillance interval. PMID:25547086

  20. Sensation seeking in males involved in recreational high risk sports

    Directory of Open Access Journals (Sweden)

    M Guszkowska

    2010-09-01

    Full Text Available The study examined sensation seeking intensity level in males involved in recreational high risk sports and investigated whether its level depends on type of sport practised. Additionally, in case of parachutists, sport experience of study participants were scrutinised with regard to its possible impact on the level of sensation seeking.The research involved 217 males aged 17 to 45, practising recreational high risk sports, namely: parachuting (n=98; wakeboarding (n=30; snowboarding (n=30; scuba diving (n=22; alpinism (n=20; paragliding (n=17. The control group included 54 men not involved in sports. Polish version of Sensation Seeking Scale (SSS-IV of Zuckerman was applied.Results show, that high risk sports males are featured by stronger need of sensations in comparison to control group and this concerned all but one aspect of sensation seeking variable. The only exception was the need of intellectual stimulation. Except from the thrill and adventure seeking dimension, type of sport may also be an important determinant of sensation seeking. Men practising snowboard and wakeboard presented stronger need for sensations, especially in the dimension of experience seeking, disinhibition and boredom susceptibility. Sport experience (number of jumps in parachuting did not differentiate the level of sensation seeking among investigated parachutists. Population of sport high risk male takers was not homogeneous, and therefore in future research one should analyse specific sports (or events in a certain sport separately.

  1. Detection of Patients at High Risk of Medication Errors

    DEFF Research Database (Denmark)

    Sædder, Eva Aggerholm; Lisby, Marianne; Nielsen, Lars Peter

    2016-01-01

    Medication errors (MEs) are preventable and can result in patient harm and increased expenses in the healthcare system in terms of hospitalization, prolonged hospitalizations and even death. We aimed to develop a screening tool to detect acutely admitted patients at low or high risk of MEs...

  2. Alcohol-Related Problems And High Risk Sexual Behaviour In ...

    African Journals Online (AJOL)

    There was a significant association between alcohol-related problems and risky sexual behavior. Alcohol-related problems are fairly common in people already infected with HIV/AIDS and are associated with high-risk sexual behavior. Thus, screening and treatment should be part of an effective HIV intervention program.

  3. Original Research Identifying patients at high risk for obstructive ...

    African Journals Online (AJOL)

    determine the factors associated with high risk for obstructive sleep apnoea and use it to identify patients at risk for the condition in ... mainstay of management is CPAP in addition to behavioral ..... the present study has some potential limitations which ... consequences of obstructive sleep apnea and short sleep duration.

  4. Awareness and prevalence of metabolic syndrome among high-risk ...

    African Journals Online (AJOL)

    MetS) in high-risk individuals attending 30 internal medicine clinics in Amman, Jordan, and also to evaluate the various factors associated with increased risk of MetS among them. Methods: This retrospective cross-sectional study was carried out ...

  5. Postmastectomy irradiation in high-risk breast cancer patients

    International Nuclear Information System (INIS)

    Overgaard, M.; Juul Christensen, J.; Johansen, H.; Nybo-Rasmussen, A.; Brincker, H.; Kooy, P. van der; Frederiksen, P.L.; Laursen, F.; Panduro, J.; Soerensen, N.E.; Gadeberg, C.C.; Hjelm-Hansen, M.; Overgaard, J.; West Andersen, K.; Zedeler, K.

    1988-01-01

    All pre- and postmenopausal high-risk breast cancer patients in the protocols DBCG 77 of the Danish Breast Cancer Cooperative Group received postmastectomy irradiation before randomization to either adjuvant systemic therapy or no such treatment. The actuarial loco-regional recurrence rate at 9 years was 6-17%, with the lowest rate in patients who also received additional adjuvant chemotherapy or tamoxifen. In a subsequent study (DBCG 82) the role of postmastectomy irradiation together with systemic treatment was evaluated in high-risk patients. Pre- and menopausal patients were randomized to postmastectomy irradiation+CMF (cyclophosphamide, methotrexate, 5-fluorouracil), CMF alone or CMF+TAM (tamoxifen). Postmenopausal patients were randomized to postmastectomy irradiation+TAM, TAM or CMF+TAM. At 4 years the loco-regional recurrence rate was significantly lower in the irradiated patients (5-7% vs. 23-33%). Further, disease-free survival was significantly improved in both pre- and postmenopausal irradiated patients compared with those who had only systemic treatment. At present, there are no significant differences between survival in the treatment groups. Thus, adjuvant systemic treatment alone (chemotherapy and/or tamoxifen) did not prevent loco-regional recurrences in high-risk patients after mastectomy and axillary lymph node sampling. However, a longer observation time is necessary to evaluate the consequence of primary optimal loco-regional tumour control in high-risk breast cancer patients with respect to survival. (orig.)

  6. Staying Alive! Training High-Risk Teams for Self Correction

    Science.gov (United States)

    Slack, Kelley; Noe, Raymond; Weaver, Sallie

    2011-01-01

    Research examining teams working in high-risk operations has been lacking. The present symposium showcases research on team training that helps to optimize team performance in environments characterized by life or death situations arising spontaneously after long periods of mundane activity by pulling experts from diverse areas of industry: space flight, health care, and medical simulation.

  7. Patients at High-Risk for Surgical Site Infection.

    Science.gov (United States)

    Mueck, Krislynn M; Kao, Lillian S

    Surgical site infections (SSIs) are a significant healthcare quality issue, resulting in increased morbidity, disability, length of stay, resource utilization, and costs. Identification of high-risk patients may improve pre-operative counseling, inform resource utilization, and allow modifications in peri-operative management to optimize outcomes. Review of the pertinent English-language literature. High-risk surgical patients may be identified on the basis of individual risk factors or combinations of factors. In particular, statistical models and risk calculators may be useful in predicting infectious risks, both in general and for SSIs. These models differ in the number of variables; inclusion of pre-operative, intra-operative, or post-operative variables; ease of calculation; and specificity for particular procedures. Furthermore, the models differ in their accuracy in stratifying risk. Biomarkers may be a promising way to identify patients at high risk of infectious complications. Although multiple strategies exist for identifying surgical patients at high risk for SSIs, no one strategy is superior for all patients. Further efforts are necessary to determine if risk stratification in combination with risk modification can reduce SSIs in these patient populations.

  8. Incidence of infective endocarditis among patients considered at high risk

    DEFF Research Database (Denmark)

    Østergaard, Lauge; Valeur, Nana; Ihlemann, Nikolaj

    2018-01-01

    Aims: Patients with prior infective endocarditis (IE), a prosthetic heart valve, or a cyanotic congenital heart disease (CHD) are considered to be at high risk of IE by guidelines. However, knowledge is sparse on the relative risk of IE between these three groups and compared controls. Methods...

  9. Update on the Management of High-Risk Penetrating Keratoplasty.

    Science.gov (United States)

    Jabbehdari, Sayena; Rafii, Alireza Baradaran; Yazdanpanah, Ghasem; Hamrah, Pedram; Holland, Edward J; Djalilian, Ali R

    2017-03-01

    In this article, we review the indications and latest management of high-risk penetrating keratoplasty. Despite the immune-privilege status of the cornea, immune-mediated graft rejection still remains the leading cause of corneal graft failure. This is particularly a problem in the high-risk graft recipients, namely patients with previous graft failure due to rejection and those with inflamed and vascularized corneal beds. A number of strategies including both local and systemic immunosuppression are currently used to increase the success rate of high-risk corneal grafts. Moreover, in cases of limbal stem cell deficiency, limbal stem cells transplantation is employed. Corticosteroids are still the top medication for prevention and treatment in cases of corneal graft rejection. Single and combined administration of immunosuppressive agents e.g. tacrolimus, cyclosporine and mycophenolate are promising adjunctive therapies for prolonging graft survival. In the future, cellular and molecular therapies should allow us to achieve immunologic tolerance even in high-risk grafts.

  10. Monitoring paneer for Listeria monocytogenes - A high risk food ...

    African Journals Online (AJOL)

    A multiplex polymerase chain reaction (PCR) assay was developed and applied to spiked and natural paneer samples to detect Listeria monocytogenes, a high risk food pathogen. The sensitivity of the assay on L. monocytogenes spiked paneer samples was 104 cells prior to enrichment, was improved to 103 cells after 4 h ...

  11. Genetic factors predisposing to homosexuality may increase mating success in heterosexuals

    NARCIS (Netherlands)

    Zietsch, B.P.; Morley, K.I.; Shekar, S.N.; Verweij, K.J.H.; Keller, M.C.; MacGregor, S.; Wright, M.J.; Bailey, J.M.; Martin, N.G.

    2008-01-01

    There is considerable evidence that human sexual orientation is genetically influenced, so it is not known how homosexuality, which tends to lower reproductive success, is maintained in the population at a relatively high frequency. One hypothesis proposes that while genes predisposing to

  12. Preferred partner characteristics in homosexual men in relation to speculated patterns of brain differentiation.

    Science.gov (United States)

    Muscarella, Frank

    2002-08-01

    The current study was designed to test a neurohormonally based theory of sexual orientation and preferred partner characteristics in homosexual men. The theory holds that the brains of homosexual men are masculinized and feminized directing attraction to targets younger and more masculine than self, and the brains of homosexual adolescents are incompletely masculinized and feminized directing attraction to targets older and more masculine than self. Ninety-six homosexual men completed questionnaires that asked them to rate morphological and behavioral characteristics associated with ethologically relevant indicators of masculinity. The participants made ratings for themselves as adolescents and adults, their current partners and idealized partners as adults, and their idealized partners as adolescents. Results of within-subjects multivariate analyses of variance supported most of the hypotheses. Participants as adults rated their idealized partners as more masculine than themselves and their real partners on five measures: height, weight, muscle development, facial hair, and sexuality. As adolescents they indicated a preference for males older and more masculine than self. The participants in adulthood did not show the predicted preference for partners younger than themselves. The increased ratings of sexuality for self from adolescence to adulthood support the contention that some additional masculinization of the brain may occur with aging. The increased ratings of body size for the idealized target from adolescence to adulthood keeps the target more masculine then self across developmental periods. This phenomenon is consistent with the speculated feminization of the brain at both periods and its effects on partner preferences.

  13. The Effects of Premarital Heterosexual and Homosexual Experience on Dating and Marriage Desirability.

    Science.gov (United States)

    Williams, John D.; Jacoby, Arthur P.

    1989-01-01

    Surveyed 365 college students to investigate their attitudes toward the effects of past sexual behavior, both heterosexual and homosexual, on one's acceptability as a dating or marriage partner. Results showed that both men and women prefer partners without previous coital or oral heterosexual experience, and both strongly rejected those with any…

  14. Spread of human T-cell leukemia virus (HTLV-I) in the Dutch homosexual community

    NARCIS (Netherlands)

    Goudsmit, J.; de Wolf, F.; van de Wiel, B.; Smit, L.; Bakker, M.; Albrecht-van Lent, N.; Coutinho, R. A.

    1987-01-01

    Sequential sera of 697 homosexual men, participating in a prospective study (1984-1986) of the risk to acquire human immunodeficiency virus (HIV) or AIDS, were tested for antibodies to human T-cell leukaemia virus (HTLV-I) by particle agglutination and immunoblotting. No intravenous drug users were

  15. The Index of Attitudes toward Homosexuals 30 Years Later: A Psychometric Study

    Science.gov (United States)

    Siebert, Darcy Clay; Chonody, Jill; Rutledge, Scott Edward; Killian, Michael

    2009-01-01

    Objective: The authors report a validation study of the Index of Attitudes toward Homosexuals (IAH) to examine its ongoing usefulness. Method: Students (n = 331) completed surveys anonymously. Exploratory factor analyses were conducted and group differences analyzed. Results: Content validity was established conceptually, and preliminary…

  16. Explaining Comfort with Homosexuality among Social Work Students: The Impact of Demographic, Contextual, and Attitudinal Factors

    Science.gov (United States)

    Swank, Eric; Raiz, Lisa

    2007-01-01

    While recent research explores the determinants of homophobia among college students, only a few studies look at the perceptions of homosexuals among social work students. Unfortunately these rare studies generally present a modest list of predictor variables or small sample sizes. To address this gap, this research explores the ways in which…

  17. "Dicks are for Chicks": Latino Boys, Masculinity, and the Abjection of Homosexuality

    Science.gov (United States)

    Mora, Richard

    2013-01-01

    Employing social constructivist theories and the concept of abjection from gender studies, this article examines how and why a group of low-income, USA-born Dominican and Puerto Rican middle-school boys constructed masculine identities by invoking and repudiating homosexuality. Ethnographic data from a 2.5-year study indicate that the abjection of…

  18. Support for Homosexuals' Civil Liberties: The Influence of Familial Gender Role Attitudes across Religious Denominations

    Science.gov (United States)

    Kenneavy, Kristin

    2012-01-01

    Religious denominations vary in both their approach to the roles that men and women play in familial contexts, as well as their approach to homosexuality. This research investigates whether gender attitudes, informed by religious tradition, predict a person's support for civil liberties extended to gays and lesbians. Using data from the 1996 and…

  19. Homosexuality – leaves from antiquity: Lesbian, gay, bisexual, and transgender population: A Tamil perspective

    Science.gov (United States)

    Somasundaram, Ottilingam; Tejus Murthy, A. G.

    2016-01-01

    Homosexuality has been present in human civilization from ancient times, and the condition as it existed in the Tamil land is described along with a reference to the terminology, concepts, and description. Some instances appear in the old Tamil classics and poems. The present legal status of this sexual orientation is also mentioned. PMID:28066015

  20. Homosexuality - leaves from antiquity: Lesbian, gay, bisexual, and transgender population: A Tamil perspective.

    Science.gov (United States)

    Somasundaram, Ottilingam; Tejus Murthy, A G

    2016-01-01

    Homosexuality has been present in human civilization from ancient times, and the condition as it existed in the Tamil land is described along with a reference to the terminology, concepts, and description. Some instances appear in the old Tamil classics and poems. The present legal status of this sexual orientation is also mentioned.

  1. Homosexuality – leaves from antiquity: Lesbian, gay, bisexual, and transgender population: A Tamil perspective

    Directory of Open Access Journals (Sweden)

    Ottilingam Somasundaram

    2016-01-01

    Full Text Available Homosexuality has been present in human civilization from ancient times, and the condition as it existed in the Tamil land is described along with a reference to the terminology, concepts, and description. Some instances appear in the old Tamil classics and poems. The present legal status of this sexual orientation is also mentioned.

  2. Access to Fertility Treatments for Homosexual and Unmarried Persons, through Iranian Law and Islamic Perspective

    Directory of Open Access Journals (Sweden)

    Reza Omani Samani

    2007-01-01

    Full Text Available Background: A family traditionally consisted of a married man, his wife, and their children. The new reproductive technologies including use of the third party as egg, sperm and embryo donation and also surrogacy have changed the traditional meanings of lineage, ancestry and family. The increasing number of lesbians and gays in addition to single women requesting fertility treatment from IVF centers in the world has brought a debate: “Can fertility treatment be offered to single persons or homosexuals?” According to ASRM and ESHRE taskforces, there is no such limitation, but as legislations and law, also ethical and social considerations depending on the culture, believes and religion of societies must be considered as limitations in some contexts like Iran.Materials and Methods: In this study we review the Iran law and also some Islamic resources about offering the fertility treatment to single mothers or homosexuals.Results: Homosexuality is not accepted in Islamic contexts and is considered as a crime. Children should have a family with both mother and father, unless they lose one of them or both. In the latter situation Islamic court will hand over the custody of the child to someone else like uncle or grandfather.Conclusion: We concluded that according to Islam and Iran’s law, fertility treatment cannot be offered to single mothers and homosexuals mostly because of welfare of the child.

  3. Finding your Soulmate: Homosexual and heterosexual age preferences in online dating

    NARCIS (Netherlands)

    Conway, J.R.; Noë, N.; Stulp, G.; Pollet, T.V.

    2015-01-01

    Heterosexual age preferences have been extensively studied by evolutionary psychologists, social psychologists, and demographers. Much less is known about such preferences in homosexual men and women. Around two decades ago, D. T. Kenrick, R. C. Keefe, A. Bryan, A. Barr, and S. Brown (1995) examined

  4. Towards tolerance. Exploring changes and explaining differences in attitudes towards homosexuality in Europe

    NARCIS (Netherlands)

    Kuyper, L.; Iedema, J.; Keuzenkamp, S.

    2013-01-01

    Across Europe, public attitudes towards lesbian, gay and bisexual (LGB) individuals range from broad tolerance to widespread rejection. Attitudes towards homosexuality are more than mere individual opinions, but form part of the social and political structures which foster or hinder the equality and

  5. Male Archetypes as Resources for Homosexual Identity Development in Gay Men.

    Science.gov (United States)

    McFarland, William P.; McMahon, Timothy R.

    1999-01-01

    The male archetypes of king, lover, magician, and warrior provide important and timeless insights into mature masculine qualities. Homosexual identity development models describe tasks that confront gay men as they move through the identity development process. Proposes that by understanding the metaphor of male archetypes, gay men will discover…

  6. Behavioral risk-reduction strategies to prevent HIV infection among homosexual men: a grounded theory approach.

    Science.gov (United States)

    de Wit, J B; Teunis, N; van Griensven, G J; Sandfort, T G

    1994-12-01

    To be able to design effective health education interventions for homosexual men, it is necessary to understand determinants of safe and unsafe sex from the perspective of those involved. In this qualitative study, therefore, an open approach was taken to allow for this perspective. Interviews were conducted with 50 randomly selected HIV-antibody negative participants in the Amsterdam Cohort Study. Detailed questions were asked about sexual interactions and behaviors with steady and nonsteady partners. Whether or not homosexual men consciously protected themselves from HIV infection and which strategy they adopted was found to depend on three major factors: 1) motivation and intention, 2) significance of anal sex, and 3) risk perception within specific relationships. From a theoretical perspective results indicate that, next to the centrality of individual motivation as postulated in both the Theory of Reasoned Action and the Theory of Planned Behavior, symbolic meaning inherent in sexual acts, as well as type of relationship are important determinants of protective sexual behaviors that have to be taken into account to understand adequately why homosexual men engage in safe or unsafe sex. Some strategies employed by homosexual men carry uncertainties that continue to put them at increased risk for HIV infection. Health education interventions can be designed to address these issues.

  7. Religiosity, Gender, Sex Anxiety, and AIDS Attitudes as They Affect Attitudes Towards Homosexuals.

    Science.gov (United States)

    Russell, C. Denise; Ellis, Jon B.

    Homophobia is a term used to describe irrational fears about, prejudice, and discrimination against homosexuals. Past research has shown that religious people were more homophobic than nonreligious ones and that these same individuals were more likely to have a high level of sex anxiety. In recent research, it has been found that with the onset of…

  8. High occurrence of extra-pair partnerships and homosexuality in a ...

    African Journals Online (AJOL)

    The Cape Vulture Gyps coprotheres is an Endangered colonial cliff-nesting species that is typically cited as monogamous. Observations of wild Cape Vulture colonies note extra-pair breeding activities but homosexual activity has never been confirmed. Observations of breeding behaviours within a captive colony were ...

  9. [Sexual partners and practices of young homosexuals in Rio de Janeiro].

    Science.gov (United States)

    Rios, Luís Felipe

    2003-01-01

    This article focuses on the organization of the erotic lives of young men who engage in homosexual practices. The reflections presented here are based on ethnographic research including observation in places of homosociability and interviews with young men in Rio de Janeiro reporting homosexual practices. By presenting erotic scenes pertaining to a homoerotic circuit and recording the sexual trajectories of young men engaging in homosexual practices, the article seeks to identify the implications of the observed erotic scripts and sex-partner patterns for the sexual health of these individuals. The text calls special attention to reports concerning the emergence of different forms of erotic interaction in childhood, as well as cross-age and crossgenerational partnerships that extend into adulthood, with a growing trend toward seeking younger partners as the young men themselves grow older. The article suggests that such phenomena require a more in-depth understanding, since they have serious implications for planning sexual health measures for young men (and boys) who engage in homosexual practices.

  10. Gallium-67 Citrate uptake in cryptoccal thyroiditis in a Homosexual male

    International Nuclear Information System (INIS)

    Machac, J.; Nejatheim, M.; Goldsmith, S.J.

    1985-01-01

    A case of disseminated cryptococcosis and autopsy proven cryptococcal thyroiditis is described in a homosexual male. Thyroid uptake of Gallium-67 citrate was seen one week prior to positive blood cultures. This finding was the sole indication of thyroid involvement. Focal Gallium uptake may be considered as an indication for biopsy and culture in the initial work up of this group of immunocompromised hosts

  11. Shared Secrets: Motherhood and Male Homosexuality in Doppelgänger Narratives

    DEFF Research Database (Denmark)

    Sencindiver, Susan Yi

    2011-01-01

    narratives. Enlisting Joseph Conrad’s short story, “The Secret Sharer,” among others, as both a paradigmatic yet self-conscious example, I examine the intersecting hotbed of these two strange bedfellows, motherhood and homosexuality, as well as the significance of gender in the male doppelgänger imaginary....

  12. The Variable Nature of Defamation: Social Mores and Accusations of Homosexuality.

    Science.gov (United States)

    Koehler, Elizabeth M.

    1999-01-01

    Contributes to scholarship on defamation, legal interpretation, and social norms by examining 59 state and federal cases decided during the last 150 years involving allegedly false accusations of homosexuality. Finds 15% of the cases resulted in a determination that it was not defamatory to call someone gay, 35% that it was defamatory, and 50%…

  13. Serial MR evaluations of human immunodeficiency virus-positive homosexual men

    International Nuclear Information System (INIS)

    Cohen, W.A.; Maravilla, K.R.; Gerlach, R.; Claypool, K.; Coombs, R.; Collier, A.

    1989-01-01

    This paper presents an evaluation of the progression of neurologic and neuropsy chological dysfunction in human immunodeficiency virus (HIV) positive homosexual men in order to define the natural history of this disease. Markers predictive of disease progression are discussed. Experimental methods and materials are included and results are assessed

  14. "Worse than dogs and pigs?" Attitudes toward homosexual practice in Zimbabwe.

    Science.gov (United States)

    Shoko, Tabona

    2010-01-01

    Politicians call them the "festering finger," endangering the body of the nation; churchmen say God wants them dead; the courts send them to jail. Zimbabwe has declared that it will not tolerate homosexuality. Gays and lesbians feel persecuted and their rights are undermined. The controversy that was ignited in 1997 when the Zimbabwean government forced the closure of a fair booth by Gays and Lesbians of Zimbabwe at the Zimbabwe International Book Fair continues to echo. At issue are fundamental questions of the scope of human rights protection in Zimbabwe and other African countries (BBC News, 1998). Such issues have sparked endless debates on homosexuality in religion, politics, and other forums. This article seeks to explore the attitudes of both traditional Shona culture and Christian sectors in Zimbabwe. The goal is to find out if the practice is rooted in Shona tradition or if it can be seen as a new phenomenon emanating from Western political and Judeo-Christian influences on Zimbabwe. The article argues that the Zimbabwean attitudes toward homosexuality combine Christian and traditional morality. Finally, the article will discuss how Christian churches and traditional Shona culture come to terms with homosexual practice today.

  15. Impact of CCR5 Delta32/+ deletion on herpes zoster among HIV-1-infected homosexual men

    NARCIS (Netherlands)

    Krol, Anneke; Lensen, Ruud; Veenstra, Jan; Prins, Maria; Schuitemaker, Hanneke; Coutinho, Roel A.

    2006-01-01

    The association between the presence of CCR5 Delta32 heterozygosity and incidence of clinical herpes zoster was studied among 296 homosexual men from the Amsterdam cohort study (ACS) infected with human immunodeficiency virus type I (HIV-1) with an estimated date of seroconversion. Of them 63 were

  16. A Discursive Construction of Homosexual Males in a Muslim-Dominant Community

    Science.gov (United States)

    Shamsudin, Zainon; Ghazali, Kamila

    2011-01-01

    This paper addresses the issue of identity construction of four young Malay homosexual men in Malaysia. Through narrative discourse of their lifeworlds (Habermas, Theory of communicative action, Polity Press, 1987), this study explores the participants' linguistic repertoire and discursive strategies in the formation, negotiation and establishment…

  17. Cutaneous Microenvironment of Human Immunodeficiency Virus (HIV)-Seropositive and HIV-Seronegative Individuals, with Special Reference to Staphylococcus aureus Colonization

    Science.gov (United States)

    Shapiro, Michael; Smith, Kathleen J.; James, William D.; Giblin, Walter J.; Margolis, David J.; Foglia, Arlene N.; McGinley, Kenneth; Leyden, James J.

    2000-01-01

    A cross-sectional quantitative study of cutaneous bacterial and yeast flora at seven body sites in 99 human immunodeficiency virus-seropositive and 50 seronegative military personnel was performed. Statistically significant differences in carriage rates were only observed for Staphylococcus aureus on the foreheads of seropositive individuals. Seronegative individuals demonstrated staphylococcal carriage rates 1.3 to 2 times as great as those of historical controls (defined as healthy individuals not receiving any medications) at five of six body sites. We conclude that seropositive military personnel do not exhibit statistically significant elevations in densities and carriage rates of the microorganisms examined (except Staphylococcus aureus), relative to seronegative individuals. Seropositive individuals may be predisposed to staphylococcal carriage. The elevated staphylococcal carriage rates of military personnel undergoing basic training warrants a formal evaluation of the impact of training exercises on cutaneous flora. The information gained may serve to limit the spread of infection during training exercises and battlefield conditions. PMID:10970352

  18. High-risk PCI: how to define it today?

    Science.gov (United States)

    DE Marzo, Vincenzo; D'Amario, Domenico; Galli, Mattia; Vergallo, Rocco; Porto, Italo

    2018-04-11

    Before the percutaneous spread, the mortality rate of patients with coronary heart disease not suitable for cardiac surgery was markedly high. This limit has been progressively exceeded with the advent of minimally invasive approaches, which, although was initially intended exclusively for low risk patients, was then employed in complex patients often too compromised to undergo cardiac surgery. Given to the rising of high-risk population, due to an increase of patients with multiple chronic conditions linked to the best care offered, we are witnessing an expansion of the high-risk percutaneous coronary interventions (PCI) population. Despite defining what high-risk is remains still unclear, all proposed definitions of high-risk PCI combine features related to three clinical areas: 1) patient risk factors and comorbidities (incorporating those which preclude surgical or percutaneous revascularization such as diabetes, COPD, CKD, lung disease, frailty, advanced age); 2) location of the disease and complexity of coronary anatomy (including multi-vessel disease, left main disease, CTO, bifurcations); 3) hemodynamic clinical status (ventricular dysfunction, concomitant valvular disease or unstable characteristics). Since cardiologists have ascertained the encouraging results in terms of efficacy and rewards compared to the low-risks patients, the important role of treating high-risk patients is becoming more and more relevant to the point that current guidelines have now changed the appropriateness of percutaneous interventions indications. Considering the complexity in managing higher-risk patients with coronary artery disease, the next step to ensure the best care for this type of patients is to create a team-based model of cooperation in order to properly establish the right treatment for the right patient.

  19. Gene- and environment-dependent neuroendocrine etiogenesis of homosexuality and transsexualism.

    Science.gov (United States)

    Dörner, G; Poppe, I; Stahl, F; Kölzsch, J; Uebelhack, R

    1991-01-01

    Sexual brain organization is dependent on sex hormone and neurotransmitter levels occurring during critical developmental periods. The higher the androgen levels during brain organization, caused by genetic and/or environmental factors, the higher is the biological predisposition to bi- and homosexuality or even transsexualism in females and the lower it is in males. Adrenal androgen excess, leading to heterotypical sexual orientation and/or gender role behavior in genetic females, can be caused by 21-hydroxylase deficiency, especially when associated with prenatal stress. The cortisol (F) precursor 21-deoxycortisol (21-DOF) was found to be significantly increased after ACTH stimulation in homosexual as compared to heterosexual females. 21-DOF was increased significantly before and even highly significantly after ACTH stimulation in female-to-male transsexuals. In view of these data, heterozygous and homozygous forms, respectively, of 21-hydroxylase deficiency represent a genetic predisposition to androgen-dependent development of homosexuality and transsexualism in females. Testicular androgen deficiency in prenatal life, giving rise to heterotypical sexual orientation and/or gender role behavior in genetic males, may be induced by prenatal stress and/or maternal or fetal genetic alterations. Most recently, in mothers of homosexual men--following ACTH stimulation--a significantly increased prevalence of high 21-DOF plasma values and 21-DOF/F ratios was found, which surpassed the mean + 1 SD level of heterosexual control women. In homosexual men as well--following ACTH stimulation--most of the 21-DOF plasma values and 21-DOF/F ratios also surpassed the mean + 1 SD level of heterosexual men. In only one out of 9 homosexual males, neither in his blood nor in that of his mother increased 21-DOF values and 21-DOF/F ratios were found after ACTH stimulation. In this homosexual man, however, the plasma dehydroepiandrosterone sulfate (DHEA-S) values and the DHEA-S/1000 x A

  20. CLINICAL AND LABORATORY PROFILE OF SPUTUM POSITIVE PULMONARY TUBERCULOSIS AMONG HIV SEROPOSITIVE AND HIV SERONEGATIVE PATIENTS- A CROSS-SECTIONAL STUDY

    Directory of Open Access Journals (Sweden)

    Amit Govind Kamat

    2017-05-01

    Full Text Available BACKGROUND The global impact of the converging dual epidemics of TB and HIV is one of the major public health challenges. The increasing rate of HIV infection in many countries has had an impact on TB epidemiology. As the prevalence of pulmonary tuberculosis is increasing among HIV seropositive patients with a wide range of immune status and clinical presentations, the present study was undertaken to assess the clinical and laboratory profile of sputum positive pulmonary tuberculosis among HIV seropositive and HIV seronegative patients. MATERIALS AND METHODS The present one year cross-sectional study was conducted in the Department of Medicine, KLES Dr. Prabhakar Kore Hospital and Medical Research Centre, Belgaum on 104 patients with sputum positive pulmonary tuberculosis patients during the period of January 2009 to December 2009. Routine investigations such as blood group, haemogram that is haemoglobin, total count, differential count, erythrocyte sedimentation rate, sputum smears for AFB and chest x-ray were done. RESULTS Seroprevalence of HIV among pulmonary tuberculosis patients was 23.08%. On examination anaemia, undernourishment, lymphadenopathy and the presence of opportunistic infections like oral candidiasis, herpes zoster stain and genital lesions were more predominant among HIV seropositives compared to HIV seronegatives. Mean Hb and TLC were significantly low among HIV seropositives compared to HIV seronegatives. Chest x-ray showed varied presentation. Upper zone infiltration, cavitation and fibrosis were more commonly involved among HIV seronegatives compared to HIV seropositives. CONCLUSION HIV seropositive PTB patients commonly present with fever, weight loss and loss of appetite, while cough with expectoration, haemoptysis, breathlessness were more common with HIV seronegative patients. Cavitation, fibrosis and fibrocavitary lesions were predominantly seen among HIV seronegatives, while infiltration and miliary mottling was

  1. La institución matrimonial después del matrimonio homosexual

    Directory of Open Access Journals (Sweden)

    Beatriz Gimeno

    2009-05-01

    Full Text Available Este artículo sostiene la idea de que el reconocimiento del matrimonio homosexual –frente a otro tipo de iniciativas–, conseguido por el movimiento LGTB español en ese país, constituye una reforma no reformista. Es decir, antes que una reivindicación conservadora, que actualiza los sentidos naturalizados en el matrimonio al imponerlos a nuevos sujetos (homosexuales, constituye un mecanismo hacia su des-institucionalización. Se trataría de una reivindicación que al tiempo que afirma la plena ciudadanía de los grupos GLTB, es decir, su reconocimiento social, deconstruye el matrimonio a través de un doble movimiento. Primero, la comprensión de esta institución como cultural y socialmente construida y por tanto, sujeta a sucesivas modificaciones a lo largo de su historia. Dos, siendo el matrimonio homosexual una contradicción en sí mismo; esto es, desde la red de sentidos y prácticas que integra, este reconocimiento conlleva el desbordamiento mismo de dicha institución.This article posits the idea that the recognition of homosexual marriage (compared to other types of initiatives which have been achieved by the Spanish LGTB movement is a non-reformist reform. That is to say rather than a conservative assertion, which modifies the naturalized character of marriage by imposing it on new subjects (homosexuals, it is a deinstitutionalization mechanism. This means that while affirming the full citizenship of the GLTB groups, in other words their social recognition, it also deconstructs marriage in two ways. Firstly, through the understanding of this institution as culturally and socially constructed and therefore subject to subsequent modifications throughout its history. Secondly, homosexual marriage being a contradiction in itself (from the point of view of an integrated network of meanings and practices reveals the ‘overflow’ of that same institution.

  2. Magnetic resonance imaging of sacroiliac joints in patients with seronegative spondyloarthritides

    Directory of Open Access Journals (Sweden)

    A. G. Bochkova

    2007-01-01

    Full Text Available Objective. To study diagnostic possibilities of magnetic resonance imaging (MRI of sacroiliac joints (SIJ in pts with seronegative spondyloarthritides (SS. Material and methods. MRI and radiological examination was performed in 15 pts: 10 with ankylosing spondylitis (AS and 5 with undifferentiated SS. MRI was done with Magnetom Symphony apparatus (Siemens, Germany with magnetic-field strength 1,5 tesla. Tl, T2 and T2-FS weighted were used. Tl-FS weighted performed in 3-4 minutes after intravenous infusion of gadolinium were additionally used in 5 pts. Inflammatory and structural (erosions, subchondral sclerosis MRI changes of SIJ were studied. Inflammatory changes of SIJ were analyzed in subchondral bone, bone marrow, joint capsule, joint cavity, interosseous ligaments. SS activity was assessed with BASDAI. Results. Median age of pts was 24 years, median SS duration — 3 years. HLA-B27 was revealed in 13 from 15 pts. All pts had radiological signs of sacroiliitis: 13 - bilateral (12 - II or III stage and 1 — I and III stage according to Kellgren, 2 — unilateral (II stage. So radiological signs of inflammation were revealed in 28 from 30 examined SIJ. MRI signs of sacroiliitis were present in the same 28 SIJ. Subchondral edema of sacrum and/or huckle-bone was revealed in 23 SIJ of 13 pts, bone marrow edema — in 20 SIJ of 13 pts, joint cavity edema - in 21 SIJ of 14 pts, capsule edema — in 12 SIJ of 8 pts, interosseous ligaments inflammation signs — in 3 SIJ of 2 pts. Inflammatory changes of all 5 examined anatomic structures were present in 1, 4 — in 9, 3 — in 13 SIJ. In 1 SIJ inflammation was localized in capsule only. Structural changes were revealed in 22 (73% SIJ of 14 pts. Structural MRI changes of SIJ at II radiological stage of sacroiliitis were noted in 67% and at III stage — in 83%. Combination of inflammatory and structural changes was present in 22 from 30 SIJ (73%. Frequency of such combination was similar at

  3. Prevalence, incidence and determinants of herpes simplex virus type 2 infection among HIV-seronegative women at high-risk of HIV infection: a prospective study in Beira, Mozambique

    NARCIS (Netherlands)

    Meque, Ivete; Dubé, Karine; Feldblum, Paul J.; Clements, Archie C. A.; Zango, Arlinda; Cumbe, Fidelina; Chen, Pai Lien; Ferro, Josefo J.; van de Wijgert, Janneke H.

    2014-01-01

    To estimate the prevalence, incidence and determinants of herpes simplex type 2 (HSV-2) infection, and associations between HSV-2 and incident HIV infection, among women at higher risk for HIV infection in Beira, Mozambique. Between 2009 and 2012, 411 women aged 18-35 years at higher risk of HIV

  4. Prevalence, incidence and determinants of herpes simplex virus type 2 infection among HIV-seronegative women at high-risk of HIV infection: a prospective study in Beira, Mozambique.

    Directory of Open Access Journals (Sweden)

    Ivete Meque

    Full Text Available To estimate the prevalence, incidence and determinants of herpes simplex type 2 (HSV-2 infection, and associations between HSV-2 and incident HIV infection, among women at higher risk for HIV infection in Beira, Mozambique.Between 2009 and 2012, 411 women aged 18-35 years at higher risk of HIV acquisition (defined as having had two or more sexual partners in the month prior to study enrollment were enrolled and followed monthly for one year. At each study visit, they were counseled, interviewed, and tested for HSV-2 and HIV antibodies.The HSV-2 prevalence at baseline was 60.6% (95% CI: 55.7% -65.4%. Increasing age (aOR = 2.94, 95% CI: 1.74-4.97, P<0.001 and aOR = 3.39, 95% CI: 1.58-7.29, P = 0.002 for age groups of 21-24 and 25-35 years old respectively, lower educational level (aOR = 1.81, 95% CI: 1.09-3.02, P = 0.022, working full time (aOR = 8.56, 95% CI: 1.01-72.53, P = 0.049 and having practiced oral sex (aOR = 3.02, 95% CI: 1.16-7.89, P = 0.024 were strongly associated with prevalent HSV-2 infection. Thirty one participants seroconverted for HSV-2 (20.5%; 95% CI: 14.4% -27.9% and 22 for HIV during the study period. The frequency of vaginal sex with a casual partner using a condom in the last 7 days was independently associated with incident HSV-2 infection (aOR = 1.91, 95% CI: 1.05-3.47, P = 0.034. Positive HSV-2 serology at baseline was not significantly associated with risk of subsequent HIV seroconversion.Young women engaging in risky sexual behaviors in Beira had high prevalence and incidence of HSV-2 infection. Improved primary HSV-2 control strategies are urgently needed in Beira.

  5. Applying the lessons of high risk industries to health care.

    Science.gov (United States)

    Hudson, P

    2003-12-01

    High risk industries such as commercial aviation and the oil and gas industry have achieved exemplary safety performance. This paper reviews how they have managed to do that. The primary reasons are the positive attitudes towards safety and the operation of effective formal safety management systems. The safety culture provides an important explanation of why such organisations perform well. An evolutionary model of safety culture is provided in which there is a range of cultures from the pathological through the reactive to the calculative. Later, the proactive culture can evolve towards the generative organisation, an alternative description of the high reliability organisation. The current status of health care is reviewed, arguing that it has a much higher level of accidents and has a reactive culture, lagging behind both high risk industries studied in both attitude and systematic management of patient risks.

  6. High risk pregnancy in the workplace. Influencing positive outcomes.

    Science.gov (United States)

    Cannon, R B; Schmidt, J V; Cambardella, B; Browne, S E

    2000-09-01

    Childbearing employees are well served by the occupational health nurse who promotes optimal preconceptual and pregnancy health practices, uses community resources, and maintains current knowledge about high risk pregnancy prevention and care. These broad goals of care can lead to decreased absenteeism, healthier and happier employees, and more positive outcomes of pregnancy. For employees with high risk pregnancies, the role of the occupational health nurse includes, but is not limited to, facilitating awareness with the employer, making suggestions for adjusting working conditions, making frequent assessments of the employee's needs, and communicating with prenatal health care providers. Occupational health nurses should never underestimate their role and potential influence on the mother, and on her significant other, for a positive outcome of her pregnancy.

  7. Physical performance following acute high-risk abdominal surgery

    DEFF Research Database (Denmark)

    Jønsson, Line Rokkedal; Ingelsrud, Lina Holm; Tengberg, Line Toft

    2018-01-01

    BACKGROUND: Acute high-risk abdominal (AHA) surgery is associated with high mortality, multiple postoperative complications and prolonged hospital stay. Further development of strategies for enhanced recovery programs following AHA surgery is needed. The aim of this study was to describe physical...... are primarily fatigue and abdominal pain. Further studies investigating strategies for early mobilization and barriers to mobilization in the immediate postoperative period after AHA surgery are needed.......BACKGROUND: Acute high-risk abdominal (AHA) surgery is associated with high mortality, multiple postoperative complications and prolonged hospital stay. Further development of strategies for enhanced recovery programs following AHA surgery is needed. The aim of this study was to describe physical...... performance and barriers to independent mobilization among patients who received AHA surgery (postoperative days [POD] 1-7). METHODS: Patients undergoing AHA surgery were consecutively enrolled from a university hospital in Denmark. In the first postoperative week, all patients were evaluated daily...

  8. High risk factors in patient with carcinoma esophagus

    International Nuclear Information System (INIS)

    Afridi, S.P.; Khan, A.; Waheed, I.

    2000-01-01

    This study was conducted to identify the presence of high risk factors in carcinoma esophagus from February, 1992 to August, 1995 at Surgical unit 1, Jinnah Postgraduate Medical Centre (JPMC), Karachi. In all 37 patients, 22 males and 15 females, were included in the study through outpatient department, surgical emergency and those referred from other cities of the country. All patients were cachectic. Diagnosis was made by detailed history, examination and laboratory investigations. Diagnosis was confirmed on barium swallow and endoscopic biopsy. Highest number of patients were in their 6th decade of life. History of snuff inhalation and opium was present in 2.7% cases each. Lower 3rd of the esophagus was affected in 62.16% middle third in 21.62% and upper third in 16.21% cases. Smoking, pan chewing, naswar eating and snuff inhalation were identified as high risk factors among patients of carcinoma esophagus. (author)

  9. Screening for breast cancer in a high-risk series

    International Nuclear Information System (INIS)

    Woodard, E.D.; Hempelmann, L.H.; Janus, J.; Logan, W.; Dean, P.

    1982-01-01

    A unique cohort of women at increased risk of breast cancer because of prior X-ray treatment of acute mastitis and their selected high-risk siblings were offered periodic breast cancer screening including physical examination of the breasts, mammography, and thermography. Twelve breast cancers were detected when fewer than four would have been expected based on age-specific breast cancer detection rates from the National Cancer institute/American Cancer Society Breast Cancer Demonstration Detection Projects. Mammograpy was positive in all cases but physical examination was positive in only three cases. Thermography was an unreliable indicator of disease. Given the concern over radiation-induced risk, use of low-dose technique and of criteria for participation that select women at high risk of breast cancer will maximize the benefit/risk ratio for mammography screening

  10. Quality assurance system for sitting high risk facilities

    International Nuclear Information System (INIS)

    Rodriguez, Aymee; Peralta, Jose L.; Fernandez, Manuel

    1999-01-01

    The paper shows how we have conceived and designed the quality assurance system for the site selection process of an area for sitting the facility of high risk in correspondence with the approved methodology. The results obtained in the implementation of the system have permitted the satisfactory performance of each one the expected stage, defining the most favorable sectors in order to continue the studies of the repository site for the disposal of low and intermedium. (author)

  11. Predicting reattendance at a high-risk breast cancer clinic.

    Science.gov (United States)

    Ormseth, Sarah R; Wellisch, David K; Aréchiga, Adam E; Draper, Taylor L

    2015-10-01

    The research about follow-up patterns of women attending high-risk breast-cancer clinics is sparse. This study sought to profile daughters of breast-cancer patients who are likely to return versus those unlikely to return for follow-up care in a high-risk clinic. Our investigation included 131 patients attending the UCLA Revlon Breast Center High Risk Clinic. Predictor variables included age, computed breast-cancer risk, participants' perceived personal risk, clinically significant depressive symptomatology (CES-D score ≥ 16), current level of anxiety (State-Trait Anxiety Inventory), and survival status of participants' mothers (survived or passed away from breast cancer). A greater likelihood of reattendance was associated with older age (adjusted odds ratio [AOR] = 1.07, p = 0.004), computed breast-cancer risk (AOR = 1.10, p = 0.017), absence of depressive symptomatology (AOR = 0.25, p = 0.009), past psychiatric diagnosis (AOR = 3.14, p = 0.029), and maternal loss to breast cancer (AOR = 2.59, p = 0.034). Also, an interaction was found between mother's survival and perceived risk (p = 0.019), such that reattendance was associated with higher perceived risk among participants whose mothers survived (AOR = 1.04, p = 0.002), but not those whose mothers died (AOR = 0.99, p = 0.685). Furthermore, a nonlinear inverted "U" relationship was observed between state anxiety and reattendance (p = 0.037); participants with moderate anxiety were more likely to reattend than those with low or high anxiety levels. Demographic, medical, and psychosocial factors were found to be independently associated with reattendance to a high-risk breast-cancer clinic. Explication of the profiles of women who may or may not reattend may serve to inform the development and implementation of interventions to increase the likelihood of follow-up care.

  12. Optimizing the Management of High-Risk, Localized Prostate Cancer

    OpenAIRE

    Sundi, Debasish; Jeong, Byong Chang; Lee, Seung Bae; Han, Misop

    2012-01-01

    Prostate cancer has a high prevalence and a rising incidence in many parts of the world. Although many screen-detected prostate cancers may be indolent, prostate cancer remains a major contributor to mortality in men. Therefore, the appropriate diagnosis and treatment of localized prostate cancer with lethal potential are of great importance. High-risk, localized prostate cancer has multiple definitions. Treatment options that should be individualized to each patient include observation, radi...

  13. Monitoring of newborns at high risk for brain injury

    OpenAIRE

    Pisani, Francesco; Spagnoli, Carlotta

    2016-01-01

    Due to the increasing number of surviving preterm newborns and to the recognition of therapeutic hypothermia as the current gold standard in newborns with hypoxic-ischaemic encephalopathy, there has been a growing interest in the implementation of brain monitoring tools in newborns at high risk for neurological disorders. Among the most frequent neurological conditions and presentations in the neonatal period, neonatal seizures and neonatal status epilepticus, paroxysmal non-epileptic motor p...

  14. Improving Asthma Communication in High-Risk Children

    OpenAIRE

    Butz, Arlene M.; Walker, Jennifer; Land, Cassia Lewis; Vibbert, Carrie; Winkelstein, Marilyn

    2007-01-01

    Few child asthma studies address the specific content and techniques needed to enhance child communication during asthma preventive care visits. This study examined the content of child and parent communications regarding their asthma management during a medical encounter with their primary care provider (PCP). The majority of parents and children required prompting to communicate symptom information to the PCP during the clinic visit. Some high-risk families may require an asthma advocate to...

  15. Improving antenatal risk assessment in women exposed to high risks.

    Science.gov (United States)

    Perry, Natasha; Newman, Louise K; Hunter, Mick; Dunlop, Adrian

    2015-01-01

    Antenatal substance use and related psychosocial risk factors are known to increase the likelihood of child protection involvement; less is known about the predictive nature of maternal reflective functioning (RF) in this population. This preliminary study assessed psychosocial and psychological risk factors for a group of substance dependent women exposed to high risks in pregnancy, and their impact on child protection involvement. Pregnant women on opiate substitution treatment (n = 11) and a comparison group (n = 15) were recruited during their third trimester to complete measures of RF (Pregnancy Interview), childhood trauma, mental health and psychosocial assessments. At postnatal follow-up, RF was reassessed (Parent Development Interview - Revised Short Version) and mother-infant dyads were videotaped to assess emotional availability (EA). Child protection services were contacted to determine if any concerns had been raised for infant safety. Significant between-group differences were observed for demographics, psychosocial factors, trauma and mental health symptoms. Unexpectedly, no significant differences were found for RF or EA between groups. Eight women in the 'exposed to high risks' group became involved with child protection services. Reflective functioning was not significantly associated with psychosocial risk factors, and therefore did not mediate the outcome of child protection involvement. Women 'exposed to high risks' were equally able to generate a model of their own and their infants' mental states and should not be seen within a deficit perspective. Further research is required to better understand the range of risk factors that predict child protection involvement in high risk groups. © The Author(s) 2013.

  16. Risk perception in women with high-risk pregnancies

    OpenAIRE

    Lee, S.

    2014-01-01

    Risk perception in women with high risk pregnancies affects the decisions they make about antenatal care and so may therefore influence the wellbeing of mother and baby. This article addresses the factors which influence women when making risk assessments and how these assessments may differ from those of healthcare professionals.\\ud \\ud Women use multiple sources of information to determine their risk status including advice from professionals, from other trusted sources, and their own intui...

  17. High risk bladder cancer: current management and survival

    Directory of Open Access Journals (Sweden)

    Anna M. Leliveld

    2011-04-01

    Full Text Available PURPOSE: To evaluate the pattern of care in patients with high risk non muscle invasive bladder cancer (NMIBC in the Comprehensive Cancer Center North-Netherlands (CCCN and to assess factors associated with the choice of treatment, recurrence and progression free survival rates. MATERIALS AND METHODS: Retrospective analysis of 412 patients with newly diagnosed high risk NMIBC. Clinical, demographic and follow-up data were obtained from the CCCN Cancer Registry and a detailed medical record review. Uni and multivariate analysis was performed to identify factors related to choice of treatment and 5 year recurrence and progression free survival. RESULTS: 74/412 (18% patients with high risk NMIBC underwent a transurethral resection (TUR as single treatment. Adjuvant treatment after TUR was performed in 90.7% of the patients treated in teaching hospitals versus 71.8 % in non-teaching hospitals (p 80 years OR 0.1 p = 0.001 and treatment in non-teaching hospitals (OR 0.25; p < 0.001 were associated with less adjuvant treatment after TUR. Tumor recurrence occurred in 191/392 (49% and progression in 84 /392 (21.4% patients. The mean 5-years progression free survival was 71.6% (95% CI 65.5-76.8. CONCLUSION: In this pattern of care study in high risk NMIBC, 18% of the patients were treated with TUR as single treatment. Age and treatment in non-teaching hospitals were associated with less adjuvant treatment after TUR. None of the variables sex, age, comorbidity, hospital type, stage and year of treatment was associated with 5 year recurrence or progression rates.

  18. Tamoxifen for women at high risk of breast cancer

    OpenAIRE

    Nazarali, Safia A; Narod, Steven A

    2014-01-01

    Safia A Nazarali, Steven A Narod Women's College Research Institute, Women's College Hospital, and The University of Toronto, Toronto, Ontario, Canada Abstract: Tamoxifen has been used as a treatment for women who have been diagnosed with breast cancer for roughly four decades and has been approved as chemoprevention for over ten years. Although tamoxifen has been proven to be beneficial in preventing breast cancer in high-risk women, its use has not been widely embraced. To ...

  19. The clinical profile of high-risk mentally disordered offenders.

    Science.gov (United States)

    Yiend, Jenny; Freestone, Mark; Vazquez-Montes, Maria; Holland, Josephine; Burns, Tom

    2013-07-01

    High-risk mentally disordered offenders present a diverse array of clinical characteristics. To contain and effectively treat this heterogeneous population requires a full understanding of the group's clinical profile. This study aimed to identify and validate clusters of clinically coherent profiles within one high-risk mentally disordered population in the UK. Latent class analysis (a statistical technique to identify clustering of variance from a set of categorical variables) was applied to 174 cases using clinical diagnostic information to identify the most parsimonious model of best fit. Validity analyses were performed. Three identified classes were a 'delinquent' group (n = 119) characterised by poor educational history, strong criminal careers and high recidivism risk; a 'primary psychopathy' group (n = 38) characterised by good educational profiles and homicide offences and an 'expressive psychopathy' group (n = 17) presenting the lowest risk and characterised by more special educational needs and sexual offences. Individuals classed as high-risk mentally disordered offenders can be loosely segregated into three discrete subtypes: 'delinquent', 'psychopathic' or 'expressive psychopathic', respectively. These groups represent different levels of risk to society and reflect differing treatment needs.

  20. Postoperative chemoradiotherapy in high risk locally advanced gastric cancer

    Energy Technology Data Exchange (ETDEWEB)

    Song, Sang Hyuk; Chie, Eui Kyu; Kim, Kyu Bo; Lee, Hyuk Joon; Yang, Han Kwang; Han, Sae Won; Oh, Do Youn; Im, Seok Ah; Bang, Yung Jue; Ha, Sung W. [Seoul National University College of Medicine, Seoul(Korea, Republic of)

    2012-12-15

    To evaluate treatment outcome of patients with high risk locally advanced gastric cancer after postoperative chemoradiotherapy. Between May 2003 and May 2012, thirteen patients who underwent postoperative chemoradiotherapy for gastric cancer with resection margin involvement or adjacent structure invasion were retrospectively analyzed. Concurrent chemotherapy was administered in 10 patients. Median dose of radiation was 50.4 Gy (range, 45 to 55.8 Gy). The median follow-up duration for surviving patients was 48 months (range, 5 to 108 months). The 5-year overall survival rate was 42% and the 5-year disease-free survival rate was 28%. Major pattern of failure was peritoneal seeding with 46%. Loco-regional recurrence was reported in only one patient. Grade 2 or higher gastrointestinal toxicity occurred in 54% of the patients. However, there was only one patient with higher than grade 3 toxicity. Despite reported suggested role of adjuvant radiotherapy with combination chemotherapy in gastric cancer, only very small portion of the patients underwent the treatment. Results from this study show that postoperative chemoradiotherapy provided excellent locoregional control with acceptable and manageable treatment related toxicity in patients with high risk locally advanced gastric cancer. Thus, postoperative chemoradiotherapy may improve treatment result in terms of locoregional control in these high risk patients. However, as these findings are based on small series, validation with larger cohort is suggested.

  1. Screening for Hypoglycemia in Exclusively Breastfed High-risk Neonates.

    Science.gov (United States)

    Singh, Princy; Upadhyay, Amit; Sreenivas, Vishnubhatla; Jaiswal, Vijay; Saxena, Pranjali

    2017-06-15

    To determine incidence of hypoglycemia in exclusively breastfed, high-risk but healthy newborns, and risk factors for its development. This observational study enrolled 407 exclusively breastfed high-risk (low birth weight newborns (1800-2499 g), late preterms, small-for-gestation, large-for-gestation and infant of diabetic mother), who did not require admission to neonatal intensive care unit and were kept in postnatal wards with mother. Hypoglycemia was defined as blood glucose £46 mg/dL (2.6 mmol/L). Blood glucose was monitored till 48 hours of life. 27% of the screened newborns developed hypoglycemia in first 48 hours. 31 (7.6%) developed recurrent (>2) episodes, 28 (6.8%) had moderate (<37mg/dL) while 8 (1.9%) developed symptomatic hypoglycemia. With increase in birthweight, risk of hypoglycemia reduced significantly (P=0.003). Hypoglycemia was observed more frequently in first 2 hours as compared to next 48 hours (P=0.0001). Low birth- weight, preterm gestation and male gender was significantly associated with increased risk of hypoglycemia. Healthy, high-risk exclusively breastfed newborns in postnatal wards need close monitoring for hypoglycemia in first 24 hrs of life.

  2. InSAR deformation monitoring of high risk landslides

    Science.gov (United States)

    Singhroy, V.; Li, J.

    2013-05-01

    During the past year there were at least twenty five media reports of landslides and seismic activities some fatal, occurring in various areas in Canada. These high risk geohazards sites requires high resolution monitoring both spatially and temporally for mitigation purposes, since they are near populated areas and energy, transportation and communication corridors. High resolution air photos, lidar and satellite images are quite common in areas where the landslides can be fatal. Radar interferometry (InSAR) techniques using images from several radar satellites are increasingly being used in slope stability assessment. This presentation provides examples of using high-resolution (1-3m) frequent revisits InSAR techniques from RADARSAT 2 and TerraSAR X to monitor several types of high-risk landslides affecting transportation and energy corridors and populated areas. We have analyses over 200 high resolution InSAR images over a three year period on geologically different landslides. The high-resolution InSAR images are effective in characterizing differential motion within these low velocity landslides. The low velocity landslides become high risk during the active wet spring periods. The wet soils are poor coherent targets and corner reflectors provide an effective means of InSAR monitoring the slope activities.

  3. Sexual orientation, theory of mind and empathy: a comparison of male homosexual and male and female heterosexuals.

    Science.gov (United States)

    Shapouri, Soheil; Nejati, Vahid; Eftekhar Ardebili, Mehrdad

    2015-01-01

    Researchers have been investigating similarities of and differences between homosexuals and heterosexuals for past few decades. Several studies have shown that in the particular domain (e.g., spatial ability), male homosexuals would resemble female heterosexuals better than male heterosexuals. Executive function, however, has received more attention than social cognition in this line of research. This study focuses on theory of mind and empathy as two important components of social cognition in male homosexuals (N=14), male heterosexuals (N=15) and female heterosexuals (N=14). Applying Reading the Mind in the Eyes test and the Empathy Quotient, no significant difference between groups was identified. This study suggests that similarities of male homosexuals and female heterosexuals may be confined to executive function and not extended to some social cognition abilities like theory of mind or empathy.

  4. Stigma towards PLWHA: The Role of Internalized Homosexual Stigma in Latino Gay/Bisexual Male and Transgender Communities

    Science.gov (United States)

    Ramirez-Valles, Jesus; Molina, Yamile; Dirkes, Jessica

    2013-01-01

    Stigma negatively affects the health of people living with HIV/AIDS (PLWHA). Negative attitudes and discriminatory actions towards PLWHA are thought to be based, among other factors, on stigma towards sexual minorities and beliefs about personal responsibility. Yet, there is little evidence to support these linkages and explain how they take place, especially among Latinos. This study analyzes attitudes towards PLWHA among 643 Latino gay/bisexual men and transgender (GBT) people. It examines whether discriminatory actions are predicted by beliefs about personal responsibility and internalized homosexual stigma. Results indicate that Discriminatory Actions towards PLWHA is associated with HIV/AIDS Personal Responsibility Beliefs and Internalized Homosexual Stigma. Further, HIV/AIDS Personal Responsibility Beliefs partially mediates the relationship between Internalized Homosexual Stigma and Discriminatory Actions towards PLWHA. Latino GBT persons who have internalized negative views about homosexuality may project those onto PLWHA. They may think PLWHA are responsible for their serostatus and, hence, deserving of rejection. PMID:23631713

  5. Stigma towards PLWHA: the role of internalized homosexual stigma in Latino gay/bisexual male and transgender communities.

    Science.gov (United States)

    Ramirez-Valles, Jesus; Molina, Yamile; Dirkes, Jessica

    2013-06-01

    Stigma negatively affects the health of people living with HIV/AIDS (PLWHA). Negative attitudes and discriminatory actions towards PLWHA are thought to be based, among other factors, on stigma towards sexual minorities and beliefs about personal responsibility. Yet, there is little evidence to support these linkages and explain how they take place, especially among Latinos. This study analyzes attitudes towards PLWHA among 643 Latino gay/bisexual men and transgender (GBT) people. It examines whether discriminatory actions are predicted by beliefs about personal responsibility and internalized homosexual stigma. Results indicate that Discriminatory Actions towards PLWHA is associated with HIV/AIDS Personal Responsibility Beliefs and Internalized Homosexual Stigma. Further, HIV/AIDS Personal Responsibility Beliefs partially mediates the relationship between Internalized Homosexual Stigma and Discriminatory Actions towards PLWHA. Latino GBT persons who have internalized negative views about homosexuality may project those onto PLWHA. They may think PLWHA are responsible for their serostatus and, hence, deserving of rejection.

  6. Crooked men and straightened women: images of homosexuality across race in two women's magazines, 1986-1995.

    Science.gov (United States)

    Gadsden, Gloria Y

    2002-01-01

    Images of traditional sexuality, across race, prevail in mass media, especially in women's magazines. While omitting less traditional sexual practices for the most part, New Woman and Essence magazines construct the image of a bisexual male who threatens the heterosexual woman and the legitimate heterosexual couple. These women's magazines also redefine homosexual activity, suggesting women who experience homosexual inclinations are really engaging in normal heterosexual behavior.

  7. Fraternal Birth Order, Family Size, and Male Homosexuality: Meta-Analysis of Studies Spanning 25 Years.

    Science.gov (United States)

    Blanchard, Ray

    2018-01-01

    The fraternal birth order effect is the tendency for older brothers to increase the odds of homosexuality in later-born males. This study compared the strength of the effect in subjects from small versus large families and in homosexual subjects with masculine versus feminine gender identities. Meta-analyses were conducted on 30 homosexual and 30 heterosexual groups from 26 studies, totaling 7140 homosexual and 12,837 heterosexual males. The magnitude of the fraternal birth order effect was measured with a novel variable, the Older Brothers Odds Ratio, computed as (homosexuals' older brothers ÷ homosexuals' other siblings) ÷ (heterosexuals' older brothers ÷ heterosexuals' other siblings), where other siblings = older sisters + younger brothers + younger sisters. An Older Brothers Odds Ratio of 1.00 represents no effect of sexual orientation; values over 1.00 are positive evidence for the fraternal birth order effect. Evidence for the reliability of the effect was consistent. The Older Brothers Odds Ratio was significantly >1.00 in 20 instances, >1.00 although not significantly in nine instances, and nonsignificantly <1.00 in 1 instance. The pooled Older Brothers Odds Ratio for all samples was 1.47, p < .00001. Subgroups analyses showed that the magnitude of the effect was significantly greater in the 12 feminine or transgender homosexual groups than in the other 18 homosexual groups. There was no evidence that the magnitude of the effect differs according to family size.

  8. The association between the fraternal birth order effect in male homosexuality and other markers of human sexual orientation

    OpenAIRE

    Rahman, Qazi

    2005-01-01

    Later fraternal birth order (FBO) is a well-established correlate of homosexuality in human males and may implicate a maternal immunization response in the feminization of male sexuality. This has led to the suggestion that FBO may relate to other markers of male sexual orientation which are robustly sexually dimorphic. If so, among homosexual males the number of older brothers should strongly correlate with traits such as spatial ability and psychological gender, indicative of greater behavi...

  9. Nivolumab-induced new-onset seronegative rheumatoid arthritis in a patient with advanced metastatic melanoma: A case report and literature review.

    Science.gov (United States)

    Haikal, Ammar; Borba, E; Khaja, Taqui; Doolittle, Gary; Schmidt, Paul

    2018-01-01

    Immune-related adverse events have been reported in patients treated with anti-programmed death-1 receptor drugs such as nivolumab. We present a case of a new-onset seronegative rheumatoid arthritis in a patient with metastatic melanoma treated with nivolumab.

  10. Diarrhoea-associated parasites in HIV-1 seropositive and sero-negative patients in a teaching hospital, Northwest Ethiopia.

    Science.gov (United States)

    Andualem, Berhanu; Kassu, Afework; Moges, Feleke; Gedefaw, Molla; Diro, Ermias; Mengistu, Getahun; Andargie, Gashaw

    2007-04-01

    to determine the prevalence and type of intestinal parasites in HIV infected and uninfected patients with diarrhea. A cross-sectional study was conducted at Gondar University hospital, Northwest Ethiopia, between March 2003 and October 2004. A total 312 consecutive diarrheic patients were included in the study. Stool specimens were collected and examined for intestinal parasites following direct, formol-ether concentration and modified acid fast staining methods. Among the patients, 63.8% were found to be HIV seropositive. The prevalence of intestinal parasites in HIV seropositive and seronegative diarrheic patients was 30.6% and 33.6%, respectively. The most prevalent parasites were Strongyoides stercoralis (9.0%) and Entamoeba histolytica (8.3%) followed by Ascaris lumbricoides (5.4%) and Cryptosporidium species (5. 1%). The prevalence of intestinal parasites in diarrheic patients was very high. Institution of appropriate intervention measures are needed to reduce morbidity in such patients.

  11. EXPERIENCE OF TREATMENT OF PATIENT WITH JUVENILE SERONEGATIVE POLYARTHRITIS WITH MEDICATION CONTAINING GLUCOSAMINE AND EXTRACTS OF ZINGIBER OFFICINALE

    Directory of Open Access Journals (Sweden)

    E.Yu. Gudkova

    2008-01-01

    Full Text Available A case report on a severe course of juvenile seronegative polyarthritis is presented in this article. Successful treatment with «zinaxin» containing glucosamine and extracts of zingiber officinale, made with lipocap technology as an alternative to nonsteroidal anti9inflammatory drugs was performed is patient with developed adverse event to the medicaments (increase of plasma levels of alanine aminotransferase and aspartate amino transferase five times a much compared to norm, combined with quadrotherapy of duodenal ulcer. Patient had a good status, pain syndrome and morning joint stiffness were absent during treatment with «zinaxin with glucosamine» daily and dsintoxication course (2 months in conditions of withdrawal of immunosuppressive treatment. activity of disease had 0–1 grade according to examination data.Key words: children, juvenile arthritis, pain syndrome.

  12. Glycomics meets artificial intelligence - Potential of glycan analysis for identification of seropositive and seronegative rheumatoid arthritis patients revealed.

    Science.gov (United States)

    Chocholova, Erika; Bertok, Tomas; Jane, Eduard; Lorencova, Lenka; Holazova, Alena; Belicka, Ludmila; Belicky, Stefan; Mislovicova, Danica; Vikartovska, Alica; Imrich, Richard; Kasak, Peter; Tkac, Jan

    2018-06-01

    In this study, one hundred serum samples from healthy people and patients with rheumatoid arthritis (RA) were analyzed. Standard immunoassays for detection of 10 different RA markers and analysis of glycan markers on antibodies in 10 different assay formats with several lectins were applied for each serum sample. A dataset containing 2000 data points was data mined using artificial neural networks (ANN). We identified key RA markers, which can discriminate between healthy people and seropositive RA patients (serum containing autoantibodies) with accuracy of 83.3%. Combination of RA markers with glycan analysis provided much better discrimination accuracy of 92.5%. Immunoassays completely failed to identify seronegative RA patients (serum not containing autoantibodies), while glycan analysis correctly identified 43.8% of these patients. Further, we revealed other critical parameters for successful glycan analysis such as type of a sample, format of analysis and orientation of captured antibodies for glycan analysis. Copyright © 2018 Elsevier B.V. All rights reserved.

  13. Diagnosis of early sacroiliitis in seronegative spondyloarthropathies by DWI and correlation of clinical and laboratory findings with ADC values

    Energy Technology Data Exchange (ETDEWEB)

    Gezmis, Esin; Donmez, Fuldem Y., E-mail: fuldemyildirim@yahoo.com; Agildere, Muhtesem

    2013-12-01

    Purpose: Sacroiliitis is one of the diagnostic criteria of seronegative SpA. The purpose of our study is to show the signal characteristics of the sacral and iliac surfaces by DWI which may contribute in early diagnosis of sacroiliitis and investigate the correlation between ADC values and clinical and laboratory parameters. Materials and methods: 62 patients with inflammatory low back pain, with a history or suspect of seronegative SpA are enrolled into the study. 40 age and sex-matched subjects without SpA constituted the control group. After obtaining routine T1 and T2 weighted sequences, echo planar imaging at b values of 0, 400 and 800 was performed. ADC values on both surfaces of the both sacroiliac joints were measured in all subjects. The CRP and sedimentation results and the presence of arthritis and enthesitis were also correlated with the ADC values. Results: ADC values on both surfaces of the both sacroiliac joints were found 0.23 × 10{sup −3} mm{sup 2}/sn in the control group. In the patient group, mean ADC value of 0.48 × 10{sup −3} mm{sup 2}/sn was obtained (p < 0.001), which was statistically significant, compatible with the increased diffusion due to medullary edema in early sacroiliitis. There was a slight correlation between CRP and ADC values; presumed to be showing the relation between the activity of the disease and the active inflammation on DWI. There was no correlation between arthritis and enthesitis and the ADC values (p > 0.001). Conclusion: DWI, by measuring ADC values, adds significant information in the early diagnosis of sacroiliitis and may help to evaluate the efficiency of the treatment.

  14. Depressive symptoms in HIV-infected and seronegative control subjects in Cameroon: Effect of age, education and gender.

    Science.gov (United States)

    Kanmogne, Georgette D; Qiu, Fang; Ntone, Félicien E; Fonsah, Julius Y; Njamnshi, Dora M; Kuate, Callixte T; Doh, Roland F; Kengne, Anne M; Tagny, Claude T; Nchindap, Emilienne; Kenmogne, Léopoldine; Mbanya, Dora; Cherner, Mariana; Heaton, Robert K; Njamnshi, Alfred K

    2017-01-01

    Depression is a leading cause of HIV/AIDS disease burden; it worsens health outcomes and quality of life. Addressing this problem requires accurate quantification of the extra burden of depression to HIV/AIDS in a given population, and knowledge of the baseline depression prevalence in the general population. There has been no previous study of depression in the general Cameroonian population. The current study attempts to address that important need. We used the Beck Depression Inventory-II to assess the prevalence and severity of depressive symptoms in 270 HIV-infected and seronegative Cameroonians. Univariate analyses showed a trend toward higher depressive symptoms among cases, compared to controls (p = 0.055), and among older subjects (>40 years), compared to younger subjects (≤40 years) (p = 0.059). Analysis of depression severity showed that 33.73% of cases had moderate-to-severe depressive symptoms, compared to 19.8% of controls (pHIV status, CD4 levels, viral loads, ART, or opportunistic infections on the risk of depressive symptoms. Both univariate and multivariable regression analyses showed significantly higher risk of depressive symptoms among females compared to males; this was significant for both female controls and female cases. Female cases had significantly higher CD4 cell counts and lower viral loads, compared to males. Both univariate and multivariable regression analyses showed that lower education (≤10 years) was associated with increased risk of depressive symptoms. This study shows a high prevalence of depressive symptoms among seronegative controls and HIV-infected Cameroonians. Integrating care for mental disorders such as depression into primary health care and existing HIV/AIDS treatment programs in Cameroon may improve the wellbeing of the general population and could lower the HIV/AIDS burden.

  15. Specialized surveillance for individuals at high risk for melanoma: a cost analysis of a high-risk clinic.

    Science.gov (United States)

    Watts, Caroline G; Cust, Anne E; Menzies, Scott W; Coates, Elliot; Mann, Graham J; Morton, Rachael L

    2015-02-01

    Regular surveillance of individuals at high risk for cutaneous melanoma improves early detection and reduces unnecessary excisions; however, a cost analysis of this specialized service has not been undertaken. To determine the mean cost per patient of surveillance in a high-risk clinic from the health service and societal perspectives. We used a bottom-up microcosting method to measure resource use in a consecutive sample of 102 patients treated in a high-risk hospital-based clinic in Australia during a 12-month period. Surveillance and treatment of melanoma. All surveillance and treatment procedures were identified through direct observation, review of medical records, and interviews with staff and were valued using scheduled fees from the Australian government. Societal costs included transportation and loss of productivity. The mean number of clinic visits per year was 2.7 (95% CI, 2.5-2.8) for surveillance and 3.8 (95% CI, 3.4-4.1) for patients requiring surgical excisions. The mean annual cost per patient to the health system was A $882 (95% CI, A $783-$982) (US $599 [95% CI, US $532-$665]); the cost discounted across 20 years was A $11,546 (95% CI, A $10,263-$12,829) (US $7839 [95% CI, US $6969-$8710]). The mean annual societal cost per patient (excluding health system costs) was A $972 (95% CI, A $899-$1045) (US $660 [95% CI, US $611-$710]); the cost discounted across 20 years was A $12,721 (95% CI, A $12,554-$14,463) (US $8637 [95% CI, US $8523-$9820]). Diagnosis of melanoma or nonmelanoma skin cancer and frequent excisions for benign lesions in a relatively small number of patients was responsible for positively skewed health system costs. Microcosting techniques provide an accurate cost estimate for the provision of a specialized service. The high societal cost reflects the time that patients are willing to invest to attend the high-risk clinic. This alternative model of care for a high-risk population has relevance for decision making about health policy.

  16. Negotiating with adversity: reflections about "race", (homosexuality and social inequality in Rio de Janeiro

    Directory of Open Access Journals (Sweden)

    Laura Moutinho

    Full Text Available The purpose of this article is to discuss how the dynamic of affection and pleasure combine with social inequality in the city of Rio de Janeiro’s GLS circuit. More specifically, it will look at part of the life trajectories of two young black homosexual men who live in the suburbs of Rio de Janeiro and of one who lives in the favela da Maré. The field work revealed that in this context the darker male homosexuals who live in the suburbs and favelas of Rio de Janeiro have a broader field of maneuver than those in which are inserted the heterosexual male and female youth of the region and even the lesbians and transvestites of different colors who live in these regions.

  17. The Lacanian Theory of Homosexuality and of the Family in Disorder

    Directory of Open Access Journals (Sweden)

    Manuel Asensi Pérez

    2017-10-01

    Full Text Available This essay aims to analyze two major problems in Jacques Lacan’s work. On the one hand, the problem of the transcription and establishment of the well known Seminar, a process through which, at times, certain problematic conclusions have been derived. Such is the case of Seminar five, Formations of the Unconscious, where Lacan apparently argues that homosexuality is a perversion. But if we take into account the manuscript of the stenotype version, it is revealed that the transcription incurs in some interpretive errors. On the other hand, the essay explores the Lacanian theory of the three Oedipal stages and points out to some contradictions in the text, contradictions that allow for a reinterpretation of Lacan’s theory in such a way that allows for a different analysis of the Lacanian vision of homosexuality, as well as of the issues related to what Roudinesco called “the family in disorder”.

  18. Identidad homosexual y contexto familiar heteroparental: implicaciones educativas para la subversión social

    Directory of Open Access Journals (Sweden)

    Marta Ceballos-Fernández

    2014-07-01

    Full Text Available Este estudio exploratorio ha sido emprendido con la finalidad de investigar, partiendo de los testimonios de personas homosexuales, el proceso de desarrollo de la identidad homosexual en el marco familiar heteroparental. Desde un criterio socioeducativo, se examina la respuesta del microsistema familiar ante este hecho, además de estudiar cómo se vive la homosexualidad en la familia de origen y otras cuestiones afines. En la investigación participan cuatro familias homoparentales españolas. A partir del empleo de una metodología cualitativa, apoyada en entrevistas en profundidad, efectuamos el pertinente análisis discursivo. Los resultados apuntan que la familia actúa como un factor de riesgo en la construcción de la identidad homosexual de los jóvenes, detectándose necesidades educativas que son discutidas al término del artículo.

  19. Vices, gods, and virtues: cosmology as a mediating factor in attitudes toward male homosexuality.

    Science.gov (United States)

    Hoffman, R J

    Using historical and anthropological evidence, the article examines the relationship of the polytheistic and monotheistic cosmologies and attitudes toward sexuality, in particular, male homosexuality. The polytheistic cosmology included the ideas of the continuity of creation, the generative forces of the universe as a whole, and gender blurring in the realm of the supernatural. In the monotheistic cosmology the godhead (Yahweh) is unborn and does not father any generations, the universe is desexualized, and the conception of gender is rigidified. The author concludes that polytheism created the conditions for a wide variety of sexual expression and sex-role behavior and did not preclude any particular form of sexual activity. In contradistinction, the monotheistic cosmology was highly restrictive of permissible male and female behavior and sexual expression and conduct. Consequently, polytheism was able to embrace the crossing of gender lines and homosexual relationships while monotheism was incapable of making these accommodations.

  20. ON A SUPPOSED INCOHERENCE BETWEEN KANT’S VIEW ON HOMOSEXUALITY AND HIS VIEW ON AUTONOMY

    Directory of Open Access Journals (Sweden)

    Cinara Nahra

    2015-07-01

    Full Text Available There are some very respectable Kant commentators who argue that Kant was not justified in using his own theory to reach the conclusions that he reached in relation to the immorality of homosexuality and some sex-related matters such as marriage and prostitution. Guyer argues that the principle that every natural organ and capacity has one and only one proper use (the teleological principle of living beings has no fundamental normative role within Kant’s moral philosophy and although Kant does use this principle, in some aspects of his treatment of human sexuality and in some of his arguments against suicide, he has no justification for doing so. From Guyer’s viewpoint, the adoption of this principle seems to be incompatible with his fundamental principle of the unconditional value of human freedom. Denis believes that appeals to nature’s purpose for particular drives constitute a limited part of Kant’s arguments for duties to ourselves, concluding that there seems to be no support for the view that homosexual sex is wrong and that it cannot, like heterosexual sex, be made permissible by being put into a context of a mutually respectful relationship. But are these the correct interpretations of Kant’s views? Is it true that a the teleological principle of living beings has no normative role in Kant’s philosophy, b that appeals to nature and the ends of nature have only a limited role in Kant’s moral philosophy and c that the right application of the Categorical imperative would never lead to the conclusions that Kant draws, that homosexuality is immoral? Here in this article it will be discussed Kant’s view on homosexuality and how Kant justifies it. The analysis carried out will show (contrarily to Guyer and Denis that the role of the teleological principle and the Formule of the Universal Law of Nature (FLUN - act as if the maxim of your action were to become by your will a universal law of nature - in Kant´s discussion of

  1. The influence of pastors’ ideologies of homosexuality on HIV prevention in the Black Church

    Science.gov (United States)

    Quinn, Katherine; Dickson-Gomez, Julia; Young, Staci

    2016-01-01

    Young, Black men who have sex with men (YBMSM) are disproportionately affected by HIV and Black churches may be a source of stigma which can exacerbate HIV risk and contribute to negative health and psychosocial outcomes. Findings from this study are based on 21 semi-structured interviews with pastors and ethnographic observation in six Black Churches. Interview transcripts and field notes were analyzed in MAXQDA using thematic content analysis. Although pastors espoused messages of love and acceptance, they overwhelmingly believed homosexuality was a sin and had difficulty accepting YBMSM into their churches. The tension around homosexuality limited pastors’ involvement in HIV prevention efforts, although there still may be opportunities for some churches. PMID:27099095

  2. The re-production of homosexually-themed discourse in educationally-based organised sport.

    Science.gov (United States)

    McCormack, Mark; Anderson, Eric

    2010-11-01

    In this study, we draw on findings from one year of participant observation and 12 in-depth interviews with men in a highly-ranked English university rugby team in order to nuance theoretical understandings concerning the re-production of homosexually-themed discourse in organised sport. We use ethnographic data to theorise the complex relationship between language, homosocial masculine relationships and organised sport. In examining the political, intentional and inadvertent effects of these men's discourses, we define and discuss the notion of gay discourse as a form of heteronormativity that is dissimilar to the traditional use of homophobic discourse. Highlighting that homosexually-themed discourse is best understood as a continuum, we stress the importance of context in interpreting the meaning and explicating the effects of this kind of discourse.

  3. Anarchism and homosexuality in Wilhelmine Germany: Senna Hoy, Erich Mühsam, John Henry Mackay.

    Science.gov (United States)

    Fähnders, W

    1995-01-01

    Homosexuality and its social and legal suppression were heatedly discussed in early twentieth-century Germany, including on the left. Among the anarchists, positions with markedly diverse forms of argument were espoused by such prominent advocates of individualist anarchism as John Henry Mackay and by others coming from the Bakuninist tradition, such as Senna Hoy and Erich Mühsam. Their writings evidence that prior to World War I and into the 1920s, German anarchists--especially when compared with the Social Democrats--intervened consistently on behalf of individual self-determination extending into the sexual sphere, even though an undercurrent of hostility toward homosexuals persisted within the leftist movement as a whole.

  4. Ciudad, subjetividad y placer. La socialización homosexual masculina en Villavicencio

    Directory of Open Access Journals (Sweden)

    Jose Miguel Segura Gutiérrez

    2017-08-01

    Full Text Available El artículo indaga por las diversas formas de socialización homosexual, ejecutadas por un grupo de varones en la ciudad de Villavicencio (Colombia y su impacto en la constitución de la subjetividad sexual. Para ello, se entrecruzan algunas descripciones de la ciudad obtenidas mediante una amplia revisión bibliográfica, que sumadas a algunos relatos sobre la experiencia homosexual masculina vivida en la ciudad, permiten plantear un vínculo entre los diversos flujos existenciales, prácticas sexuales y modos de vida gestados por hombres homosexuales al interior del espacio citadino. La ciudad con sus instituciones y reglas sigue siendo el medio para ejercer poder sobre el cuerpo y los placeres de sus agregados, a través de un proceso dinámico, que transita entre la individuación singular y la modulación social.

  5. Conducta homosexual en estudiantes universitarios y aspectos diferenciales de género

    Directory of Open Access Journals (Sweden)

    José Moral de la Rubia

    2009-01-01

    Full Text Available Los objetivos del estudio son estimar la prevalencia de conductas y fantasías homosexuales en estudiantes de psicología y ver su asociación con el coito vaginal, penetración anal y uso del preservativo, además de predecir conductas homosexuales. Se empleó una muestra de 395 sujetos. El instrumento de medida fue una encuesta de sexualidad. El 21% ha tenido fantasías homosexuales, sin diferencia de género. El 4% ha mantenido, al menos, una relación homosexual, con diferencia de género (10% hombres y 2% mujeres. El haber sufrido abuso sexual estaba relacionado con conducta homosexual. El predictor más importante fue tener fantasías homosexuales. El 14% de hombres y 50% de mujeres con conductas homosexuales han mantenido relaciones heterosexuales con coito vaginal.

  6. Teamwork in high-risk environments analogous to space

    Science.gov (United States)

    Kanki, Barbara G.

    1990-01-01

    Mountaineering expeditions combine a number of factors which make them potentially good analogs to the planetary exploration facet of long-duration space missions. A study of mountain climbing teams was conducted in order to evaluate the usefulness of the environment as a space analog and to specifically identify the factors and issues surrounding teamwork and 'successful' team performance in two mountaineering environments. This paper focuses on social/organizational factors, including team size and structure, leadership styles and authority structure which were found in the sample of 22 climb teams (122 individuals). The second major issue discussed is the construction of a valid performance measure in this high-risk environment.

  7. Gender dysphoria with homosexuality and comorbid depressive disorder: complexities in concept and management

    OpenAIRE

    M. S. Bhatia; Priyanka Gautam

    2015-01-01

    Gender identity disorder (GID) and homosexuality are complex entities debated over decades, whether should be categorized as a disorder or not. There are a number of problems specifically related to the criteria of the GID diagnosis like differences in the terms trans-sexualism and GID, failure of the proposed criteria in conceptualizing the whole spectrum of gender variance phenomena, the potential risk of physically invasive examinations to rule out intersex conditions and the application o...

  8. PROBLEMS OF HOMOSEXUALITY PERCEPTION IN MODERN RUSSIA: GROUNDS OF THE RELEVANT DISCOURSE

    Directory of Open Access Journals (Sweden)

    Vadim Vadimovich Kortunov

    2015-11-01

    Full Text Available In 2013, the State Duma of the Russian Federation adopted the Federal Law «On the prohibition of propaganda of nontraditional sexual relations among minors», which provoked a lot of discussions in the media between sexual minorities and their opponents: the former began to criticize this law as the one prejudicing their rights, the latter after a long silence renewed their attacks against homosexuals. It served as a basis for sociologists to assume that homophobia is reviving in Russia. In the article we made an attempt to see into the arguments of opponents of nontraditional sexual orientation and to trace the belief origins of «Russian homophobia». To do this, the authors of this scoping study are trying to answer the following questions: is it correct to justify homosexuality as a norm of behavior, referring to homosexual behavior of animals, to what extent is homosexuality due to the norms of the Russian culture, what its contribution to the art, what do the world religions say about same-sex relationships, what is its impact on the society development, what is the opinion of modern medicine on this phenomenon. In this paper the authors attempt to reproduce the arguments of homophobic logic, which is so widespread in today’s Russia, to understand its origins and ideological grounds. This is done solely in order to find compromises and to develop balanced, tolerant positions from both sides. The authors hope that the ideas expressed in this article will be helpful in the matter of resolving such significant socio-cultural issue as the opposition of homo- and heterosexuals, and will make a modest contribution to the protection of human rights and freedoms in the Russian Federation.

  9. From Ridiculed Deviants towards Normal Citizens. The Representation of Homosexuals in the Finnish Media 1990 - 2010

    OpenAIRE

    Ylppö, Myrsky

    2016-01-01

    This thesis explores how the Finnish media’s representations of homosexual men and women changed between 1990 and 2010, from negative public portrayals towards more positive ones. The thesis also examines if these changes reflect attitudes and opinions of the Finnish society and population overall during this time period. The primary sources consist of newspaper articles from the newspaper Helsingin Sanomat, along with material from other newspapers, tabloids, and supporting research material...

  10. The Power to Raise and Support Armies: The Homosexual Exclusion Policy in Perspective

    Science.gov (United States)

    1991-01-01

    is a pedophile , the fact that he is an anti-social personality and he has sodomized a child in the past make it more likely that he will commit such an...act in the future." Id. at 730. A fortiorari if plaintiff declared himself to be a pedophile , the prison could properly withhold the NAMBLA materials...730 ("inmates who are identified as or suspected of being pedophiles or homosexuals are a favorite target for violence since many incarcerated felons

  11. ‘It is what it is’: Masculinity, homosexuality, and inclusive discourse in mixed martial arts

    OpenAIRE

    Channon, Alex; Matthews, Christopher R.

    2015-01-01

    In this paper we make use of inclusive masculinity theory to explore online media representations of male homosexuality and masculinity within the increasingly popular combat sport of mixed martial arts (MMA). Adopting a case-study approach, we discuss narratives constructed around one aspirational male MMA fighter, Dakota Cochrane, whose history of having participated in gay pornography became a major talking point on a number of MMA ‘fanzine’/‘community’ websites during early 2012. While th...

  12. Prevalence of Mycoplasma genitalium in men with urethritis and in high risk asymptomatic males in Tel Aviv: a prospective study.

    Science.gov (United States)

    Gottesman, Tamar; Yossepowitch, Orit; Samra, Zmira; Rosenberg, Shoshana; Dan, Michael

    2017-02-01

    We sought to investigate the prevalence of Mycoplasma genitalium, Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis in men presenting to a sexually transmitted infection (STI) clinic, with special attention to M. genitalium, its occurrence in Israeli patients, coinfections, and risk factors. In a cross-sectional study, 259 men were successively enrolled in the Tel Aviv Levinsky Clinic for STIs between November 2008 and November 2010. There were 118 men with urethritis and 141 high-risk men without symptoms. M. genitalium, C. trachomatis, N. gonorrhoeae, and T. vaginalis were detected using nucleic acid amplification tests. Demographic characteristics and risk factors were documented. The overall prevalence of infection with M. genitalium, C. trachomatis, N. gonorrhoeae, and T. vaginalis, were 6.6%, 12.7%, 23.1%, and 0%, respectively. Prevalences in men with urethritis were 11.9%, 22%, and 49%, for M. genitalium, C. trachomatis, and N. gonorrhoeae, respectively. Prevalences in men without symptoms were 2.1%, 5.0%, and 1.4%, for M. genitalium, C. trachomatis, and N. gonorrhoeae, respectively. Co-infections were found only in symptomatic individuals, in whom 5.9% were infected concomitantly with C. trachomatis and N. gonorrhoeae, and 2.5% had dual infection with M. genitalium and N. gonorrhoeae. N. gonorrhoeae, C. trachomatis, and M. genitalium were significantly more prevalent in patients with urethritis. M. genitalium was significantly more prevalent in the heterosexual population than in homosexual males. To conclude, we have found that M. genitalium infection is associated with urethritis in Israeli men, and more so in the heterosexual population. Testing men for M. genitalium as a cause of non-gonococcal urethritis is warranted, particularly because of its poor response to doxycycline and possible failure of azithromycin.

  13. Neural Correlates of Sexual Orientation in Heterosexual, Bisexual, and Homosexual Men

    Science.gov (United States)

    Safron, Adam; Sylva, David; Klimaj, Victoria; Rosenthal, A. M.; Li, Meng; Walter, Martin; Bailey, J. Michael

    2017-01-01

    Studies of subjective and genital sexual arousal in monosexual (i.e. heterosexual and homosexual) men have repeatedly found that erotic stimuli depicting men’s preferred sex produce strong responses, whereas erotic stimuli depicting the other sex produce much weaker responses. Inconsistent results have previously been obtained in bisexual men, who have sometimes demonstrated distinctly bisexual responses, but other times demonstrated patterns more similar to those observed in monosexual men. We used fMRI to investigate neural correlates of responses to erotic pictures and videos in heterosexual, bisexual, and homosexual men, ages 25–50. Sixty participants were included in video analyses, and 62 were included in picture analyses. We focused on the ventral striatum (VS), due to its association with incentive motivation. Patterns were consistent with sexual orientation, with heterosexual and homosexual men showing female-favoring and male-favoring responses, respectively. Bisexual men tended to show less differentiation between male and female stimuli. Consistent patterns were observed in the whole brain, including the VS, and also in additional regions such as occipitotemporal, anterior cingulate, and orbitofrontal cortices. This study extends previous findings of gender-specific neural responses in monosexual men, and provides initial evidence for distinct brain activity patterns in bisexual men. PMID:28145518

  14. Understanding Adoption by Homosexual Pairs According to the Professionals Acting in These Procedures: An Exploratory Study

    Directory of Open Access Journals (Sweden)

    Fábio de Carvalho Mastroianni

    2014-06-01

    Full Text Available The Brazilian legislation that regularizes stable union and the marriage between homosexuals is recent and matters related to this theme still generate discussions. The aim of this paper was to explore the understanding of psychologists and social workers that act in adoption processes about this new possibility. A qualitative research was developed with these professionals, by means of a semi-structured interview, and the answers were analyzed using the content analysis technique. The sample was formed by 7 (seven individuals, all of the feminine sex, with professional education in their respective areas. The participants, even reporting no direct experience with adoption by homosexual pairs, described situations which they came across with this type of relationship in processes of another nature, different from joint adoption, allowing them to explore their comprehension about the subject. It was verified that adoption itself already involves myths and prejudices, but the professionals feel ready and satisfied in acting in these procedures. The same, however, isn't observed in the adoption by homosexual couples, having recognized their necessity of a greater prepare and reflection to act in these processes. It is an exploratory study which is limited to a small group of individuals of the universe of professionals who act in these procedures. Although this study doesn't allow us to offer more comprehensive considerations about this subject, it intends to present subsidies for an initial discussion.

  15. The abject gaze and the homosexual body: Flandrin's Figure d'Etude.

    Science.gov (United States)

    Camille, M

    1994-01-01

    This article charts the history of the reception, reproduction and appropriation of a single image that has recently become a kind of "gay icon"--the Figure d'Etude in the Louvre, painted by Hippolyte Flandrin in 1835. Initially no more than a neo-classical academic exercise, the formal emptiness of this picture meant that it could be re-invested and reinscribed with new meanings and new titles at every turn. Emblematic of the anxious visibility/invisibility of the newly discovered homosexual body during a period when the gaze still had to be kept a dark secret, Flandrin's image only "came out" in its later photographic reworkings by Frederick Holland Day and Baron von Gloeden. After being reproduced for a specifically homosexual audience early this century, the popular Romantic pose of the young man curled-up in profile became a standard one, reappearing recently in the photographs of Robert Mapplethorpe. The inactive, abject and inward-turned isolation of the figure with its narcissistic self-absorption makes it, in my view, a profoundly negative stereotype of the gay gaze and the homosexual body. Flandrin's figure nonetheless appears today on gay merchandise world-wide as a sign of our separate and secluded subject positions and our community's unwillingness to radically alter older imposed and inherited classical stereotypes.

  16. Queer diagnoses revisited: The past and future of homosexuality and gender diagnoses in DSM and ICD.

    Science.gov (United States)

    Drescher, Jack

    2015-01-01

    The American Psychiatric Association (APA) recently completed a several year process of revising the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). During that time, there were objections raised to retaining DSM's gender identity disorder diagnoses and calls to remove them, just as homosexuality had been removed from DSM-II in 1973. At the conclusion of the DSM-5 revision process, the gender diagnoses were retained, albeit in altered form and bearing the new name of 'gender dysphoria'. The author of this paper was a member of the DSM-5 Workgroup on Sexual and Gender Identity Disorders and presently serves on the WHO Working Group on Sexual Disorders and Sexual Health. Both groups faced similar tasks: reconciling patients' needs for access to care with the stigma of being given a psychiatric diagnosis. The differing nature of the two diagnostic manuals led to two different outcomes. As background, this paper updates the history of homosexuality and the gender diagnoses in the DSM and in the International Statistical Classification of Diseases and Related Health Problems (ICD) as well as what is expected to happen to the homosexuality and gender diagnoses following the current ICD-11 revision process.

  17. Study of deaths by suicide of homosexual prisoners in Nazi Sachsenhausen concentration camp.

    Science.gov (United States)

    Cuerda-Galindo, Esther; López-Muñoz, Francisco; Krischel, Matthis; Ley, Astrid

    2017-01-01

    Living conditions in Nazi concentration camps were harsh and inhumane, leading many prisoners to commit suicide. Sachsenhausen (Oranienburg, Germany) was a concentration camp that operated from 1936 to 1945. More than 200,000 people were detained there under Nazi rule. This study analyzes deaths classified as suicides by inmates in this camp, classified as homosexuals, both according to the surviving Nazi files. This collective was especially repressed by the Nazi authorities. Data was collected from the archives of Sachsenhausen Memorial and the International Tracing Service in Bad Arolsen. Original death certificates and autopsy reports were reviewed. Until the end of World War II, there are 14 death certificates which state "suicide" as cause of death of prisoners classified as homosexuals, all of them men aged between 23 and 59 years and of various religions and social strata. Based on a population of 1,200 prisoners classified as homosexuals, this allows us to calculate a suicide rate of 1,167/100,000 (over the period of eight years) for this population, a rate 10 times higher than for global inmates (111/100,000). However, our study has several limitations: not all suicides are registered; some murders were covered-up as suicides; most documents were lost during the war or destroyed by the Nazis when leaving the camps and not much data is available from other camps to compare. We conclude that committing suicides in Sachsenhausen was a common practice, although accurate data may be impossible to obtain.

  18. Relationship between PLAP and high-risk pregnancy

    International Nuclear Information System (INIS)

    Yu Huixin; Xiao Weihong; Cao Guoxian; Li Weiyi; Shen Bo

    2001-01-01

    PLAP was isolated and purified from human placenta and the antiserum was obtained by immunizing the rabbits. A radioimmunoassay of PLAP (PLAP RIA) was established by labelling the antigen using the chloramine-T method. Its sensitivity was 1.54 μg/L, the recovery rate was between 96.7% and 105.2%, the intra- and inter-assay CV were 8.94% and 9.43%, respectively, the antiserum provided a linear response from 2 to 1000 μg/L. The assay has no cross-reactivity with liver AP. Serum level of PLAP were measured by PLAP RIA in 649 cases of normal pregnancy and 164 cases of high-risk pregnancy. The results indicated that the PLAP level increased proportionally with the advance of gestational age (r = 0.9843). In 33 cases of pregnancy induced hypertension and 21 cases of intrauterine fetal growth retardation, the PLAP were at significantly low level. In 7 cases of neonatal asphyxia and 26 cases of fetal distress, the PLAP level in the mother's serum were also low. In 53 cases of intrahepatic cholestasis of pregnancy, the PLAP level were similar to those of normal pregnancy. This study illustrated that PLAP RIA can play an important role in evaluation of placental function and fetal prognosis for cases of high-risk pregnancy

  19. Oral health status of women with high-risk pregnancies.

    Science.gov (United States)

    Merglova, Vlasta; Hecova, Hana; Stehlikova, Jaroslava; Chaloupka, Pavel

    2012-12-01

    The aim of this study was to investigate the oral health status of women with high-risk pregnancies. A case-control study of 142 pregnant women was conducted. The case group included 81 pregnant women with high-risk pregnancies, while 61 women with normal pregnancies served as controls. The following variables were recorded for each woman: age, general health status, DMF, CPITN, and PBI index, amounts of Streptococcus mutans in the saliva and dental treatment needs. The Mann-Whitney test, Kruskal-Wallis test, t-test and chi-squared test were used for statistical analyses. Statistically significant differences were detected between the PBI indices and dental treatment needs of the two groups. Out of the entire study cohort, 77% of the women in the case group and 52% of the women in the control group required dental treatment. In this study, women with complications during pregnancy had severe gingivitis and needed more frequent dental treatment than those in the control group.

  20. Personality differences in high risk sports amateurs and instructors.

    Science.gov (United States)

    Watson, Alison E; Pulford, Briony D

    2004-08-01

    This study investigated the personality differences of 21 amateurs and 20 instructors who participated in the high risk sports of skydiving, hang-gliding, paragliding, scuba diving, microlighting, and rock climbing, versus those who did not. 38 men and 28 women (M age=32.6 yr., SD= 10.0) were assessed using the Eysenck Personality Questionnaire-Revised, the General Health Questionnaire, the Generalised Self-efficacy Scale, and a Type A/B personality measure. Instructors and Amateurs scored significantly higher on Extroversion and lower on Neuroticism than Nonparticipants; however, they differed from each other on the General Health Questionnaire and Type A/B personality scores. Amateurs scored significantly higher on Psychoticism and Self-efficacy than Instructors and Nonparticipants. In conclusion, these test scores suggest that people who are attracted to high risk sports tend to be at the extroverted and emotionally stable end of the scale, with a tendency to exhibit Type A characteristics; however, Instructors' scores on Psychoticism and Self-efficacy are more akin to those of Nonparticipants.

  1. High-Risk Stress Fractures: Diagnosis and Management.

    Science.gov (United States)

    McInnis, Kelly C; Ramey, Lindsay N

    2016-03-01

    Stress fractures are common overuse injuries in athletes. They occur during periods of increased training without adequate rest, disrupting normal bone reparative mechanisms. There are a host of intrinsic and extrinsic factors, including biochemical and biomechanical, that put athletes at risk. In most stress fractures, the diagnosis is primarily clinical, with imaging indicated at times, and management focused on symptom-free relative rest with advancement of activity as tolerated. Overall, stress fractures in athletes have an excellent prognosis for return to sport, with little risk of complication. There is a subset of injuries that have a greater risk of fracture progression, delayed healing, and nonunion and are generally more challenging to treat with nonoperative care. Specific locations of high-risk stress fracture include the femoral neck (tension side), patella, anterior tibia, medial malleolus, talus, tarsal navicular, proximal fifth metatarsal, and great toe sesamoids. These sites share a characteristic region of high tensile load and low blood flow. High-risk stress fractures require a more aggressive approach to evaluation, with imaging often necessary, to confirm early and accurate diagnosis and initiate immediate treatment. Treatment consists of nonweight-bearing immobilization, often with a prolonged period away from sport, and a more methodic and careful reintroduction to athletic activity. These stress fractures may require surgical intervention. A high index of suspicion is essential to avoid delayed diagnosis and optimize outcomes in this subset of stress fractures. Copyright © 2016 American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.

  2. Relationship between PLAP and high-risk pregnancy

    Energy Technology Data Exchange (ETDEWEB)

    Huixin, Yu; Weihong, Xiao; Guoxian, Cao; Weiyi, Li; Bo, Shen [Jiangsu Inst. of Nuclear Medicine, Wuxi (China). National Key Laboratory of Nuclear Medicine

    2001-04-01

    PLAP was isolated and purified from human placenta and the antiserum was obtained by immunizing the rabbits. A radioimmunoassay of PLAP (PLAP RIA) was established by labelling the antigen using the chloramine-T method. Its sensitivity was 1.54 {mu}g/L, the recovery rate was between 96.7% and 105.2%, the intra- and inter-assay CV were 8.94% and 9.43%, respectively, the antiserum provided a linear response from 2 to 1000 {mu}g/L. The assay has no cross-reactivity with liver AP. Serum level of PLAP were measured by PLAP RIA in 649 cases of normal pregnancy and 164 cases of high-risk pregnancy. The results indicated that the PLAP level increased proportionally with the advance of gestational age (r = 0.9843). In 33 cases of pregnancy induced hypertension and 21 cases of intrauterine fetal growth retardation, the PLAP were at significantly low level. In 7 cases of neonatal asphyxia and 26 cases of fetal distress, the PLAP level in the mother's serum were also low. In 53 cases of intrahepatic cholestasis of pregnancy, the PLAP level were similar to those of normal pregnancy. This study illustrated that PLAP RIA can play an important role in evaluation of placental function and fetal prognosis for cases of high-risk pregnancy.

  3. A comparative analysis of homosexual behaviors, sex role preferences, and anal sex proclivities in Latino and non-Latino men.

    Science.gov (United States)

    Jeffries, William L

    2009-10-01

    Machismo prescribes that homosexual encounters among Latino men are conducted along highly gendered lines: men tend to be anally insertive or receptive over the lifecourse, but not both. Some have argued that Latino men have more lifecourse homosexual behaviors in comparison to other racial/ethnic groups. This is often due to the perception that Latin America has quasi-institutionalized homosexuality, which sharply contrasts it with the United States. Although scholars suggest that sex role preferences and greater likelihoods for homosexual behaviors exist among Latino men in the United States, limited empirical data validate these claims. Latino/non-Latino differences in male homosexual behaviors and sex role preferences were analyzed by using the 2002 cycle of the National Survey of Family Growth, a nationally representative, probability sample of 4,928 men. Findings revealed that non-Mexican Latino, but not Mexican, men had increased likelihoods of ever having anal sex than non-Latino Whites and oral sex than non-Latino Blacks. These relationships remained after controlling for age, education, and foreign birth. Latino men preferred insertive or receptive sex in comparison to non-Latino Blacks and Whites, but this difference disappeared after education was controlled. In full and reduced models, Mexican men tended to be orifice-specific (oral or anal), while non-Mexican Latinos were more oriented to both oral and anal sex. Controlling for other factors, all Latinos were more likely than non-Latino Blacks and Whites to refuse to answer male homosexual behavior questions. The implications of race/ethnicity are discussed for homosexual behavior patterns among U.S. men.

  4. The Global Online Sexuality Survey (GOSS): male homosexuality among Arabic-speaking internet users in the Middle East--2010.

    Science.gov (United States)

    Shaeer, Osama; Shaeer, Kamal

    2014-10-01

    The prevalence of male homosexuality is difficult to elicit considering the sensitivity of one's sexual orientation. The Global Online Sexuality Survey (GOSS) is an online epidemiologic study of male and female sexuality. The online nature of GOSS allows more confidentiality and wider geographic reach, particularly important in investigating sexual issues within the more conservative societies. This study aims to determine the prevalence of male homosexuality among Internet users in the Arabic-speaking Middle East and the unique characteristics of this subset of the population. Prevalence of male homosexuality. In the year 2010, GOSS was offered to Arabic-speaking web surfers above 18 years of age in the Middle East. Potential participants were invited via advertising on Facebook®. Invitations were dispatched randomly with the exception of geographic region and age, regardless web surfing preferences. GOSS relied in part on validated questionnaires such as the International Index of Erectile Function, as well on other nonvalidated questions. 17.1% reported desire toward the same sex, of whom 5.6% had homosexual encounters, mostly in the form of external stimulation rather than intercourse, and exclusively undercover. An overwhelming majority was ego-dystonic (78.2%). This is--to our knowledge--the first online survey to address the prevalence of homosexual orientation and practice in the Middle East, discriminating desire from practice, ego-syntonic from ego-dystonic, and investigating the pattern of practice. Homosexual desire is present in the Middle East as it is around the world, and homosexual encounters are as prevalent. Yet, the undercover and ego-dystonic states prevail. © 2014 International Society for Sexual Medicine.

  5. Characterizing and Reaching High-Risk Drinkers Using Audience Segmentation

    Science.gov (United States)

    Moss, Howard B.; Kirby, Susan D.; Donodeo, Fred

    2010-01-01

    Background Market or audience segmentation is widely used in social marketing efforts to help planners identify segments of a population to target for tailored program interventions. Market-based segments are typically defined by behaviors, attitudes, knowledge, opinions, or lifestyles. They are more helpful to health communication and marketing planning than epidemiologically-defined groups because market-based segments are similar in respect to how they behave or might react to marketing and communication efforts. However, market segmentation has rarely been used in alcohol research. As an illustration of its utility, we employed commercial data that describes the sociodemographic characteristics of high-risk drinkers as an audience segment; where they tend to live, lifestyles, interests, consumer behaviors, alcohol consumption behaviors, other health-related behaviors, and cultural values. Such information can be extremely valuable in targeting and planning public health campaigns, targeted mailings, prevention interventions and research efforts. Methods We describe the results of a segmentation analysis of those individuals who self-report consuming five or more drinks per drinking episode at least twice in the last 30-days. The study used the proprietary PRIZM™ audience segmentation database merged with Center for Disease Control and Prevention's (CDC) Behavioral Risk Factor Surveillance System (BRFSS) database. The top ten of the 66 PRIZM™ audience segments for this risky drinking pattern are described. For five of these segments we provide additional in-depth details about consumer behavior and the estimates of the market areas where these risky drinkers reside. Results The top ten audience segments (PRIZM clusters) most likely to engage in high-risk drinking are described. The cluster with the highest concentration of binge drinking behavior is referred to as the “Cyber Millenials.” This cluster is characterized as “the nation's tech-savvy singles

  6. Characterizing and reaching high-risk drinkers using audience segmentation.

    Science.gov (United States)

    Moss, Howard B; Kirby, Susan D; Donodeo, Fred

    2009-08-01

    Market or audience segmentation is widely used in social marketing efforts to help planners identify segments of a population to target for tailored program interventions. Market-based segments are typically defined by behaviors, attitudes, knowledge, opinions, or lifestyles. They are more helpful to health communication and marketing planning than epidemiologically defined groups because market-based segments are similar in respect to how they behave or might react to marketing and communication efforts. However, market segmentation has rarely been used in alcohol research. As an illustration of its utility, we employed commercial data that describes the sociodemographic characteristics of high-risk drinkers as an audience segment, including where they tend to live, lifestyles, interests, consumer behaviors, alcohol consumption behaviors, other health-related behaviors, and cultural values. Such information can be extremely valuable in targeting and planning public health campaigns, targeted mailings, prevention interventions, and research efforts. We described the results of a segmentation analysis of those individuals who self-reported to consume 5 or more drinks per drinking episode at least twice in the last 30 days. The study used the proprietary PRIZM (Claritas, Inc., San Diego, CA) audience segmentation database merged with the Center for Disease Control and Prevention's (CDC) Behavioral Risk Factor Surveillance System (BRFSS) database. The top 10 of the 66 PRIZM audience segments for this risky drinking pattern are described. For five of these segments we provided additional in-depth details about consumer behavior and the estimates of the market areas where these risky drinkers resided. The top 10 audience segments (PRIZM clusters) most likely to engage in high-risk drinking are described. The cluster with the highest concentration of binge-drinking behavior is referred to as the "Cyber Millenials." This cluster is characterized as "the nation's tech

  7. Cyberbullying in those at clinical high risk for psychosis.

    Science.gov (United States)

    Magaud, Emilie; Nyman, Karissa; Addington, Jean

    2013-11-01

    Several studies suggest an association between experiences of childhood trauma including bullying and the development of psychotic symptoms. The use of communications technology has created a new media for bullying called 'cyberbullying'. Research has demonstrated associations between traditional bullying and cyberbullying. Negative effects of cyberbullying appear similar in nature and severity to the reported effects of traditional bullying. Our aim was to examine the prevalence and correlates of cyberbullying in those at clinical high risk (CHR) for psychosis. Fifty young people at CHR for psychosis were administered the Childhood Trauma Questionnaire with added questions about cyberbullying. Cyberbullying was reported in 38% of the sample. Those who experienced cyberbullying also reported experiencing previous trauma. It is possible that cyberbullying may be a problem for those at CHR of psychosis, and due to the vulnerable nature of these young people may have longitudinal implications. © 2013 Wiley Publishing Asia Pty Ltd.

  8. Early detection of psychosis: finding those at clinical high risk.

    Science.gov (United States)

    Addington, Jean; Epstein, Irvin; Reynolds, Andrea; Furimsky, Ivana; Rudy, Laura; Mancini, Barbara; McMillan, Simone; Kirsopp, Diane; Zipursky, Robert B

    2008-08-01

    In early detection work, recruiting individuals who meet the prodromal criteria is difficult. The aim of this paper was to describe the development of a research clinic for individuals who appear to be at risk of developing a psychosis and the process for educating the community and obtaining referrals. The outcome of all referrals to the clinic over a 4-year period was examined. Following an ongoing education campaign that was over inclusive in order to aid recruitment, approximately 27% of all referrals met the criteria for being at clinical high risk of psychosis. We are seeing only a small proportion of those in the community who eventually go on to develop a psychotic illness. This raises two important issues, namely how to remedy the situation, and second, the impact of this on current research in terms of sampling bias and generalizability of research findings. © 2008 The Authors. Journal compilation © 2008 Blackwell Publishing Asia Pty Ltd.

  9. Recommendations of activity restriction in high-risk pregnancy scenarios

    DEFF Research Database (Denmark)

    Bendix, Jane; Hegaard, Hanne Kristine; Bergholt, Thomas

    2015-01-01

    activity restriction more often than obstetricians in five of the nine scenarios, in women with preterm premature rupture of membranes, preterm labour, cervical ripening, total placenta praevia, and intrauterine growth restriction, whereas no differences were found in the remaining scenarios. Compared...... to the obstetricians, the midwives also reported that they expected the recommendation to be more effective. Most midwives and obstetricians reported that they thought strict activity restriction was associated with severe or moderate adverse effect, and recommended antithrombotic prophylaxis. Conclusions: Danish...... obstetricians and midwives prescribe activity restriction in most high-risk pregnancies. The degree of activity restriction and the presumed effect vary between clinicians. This may reflect different attitudes and lack of guidelines based on clinical studies of a possible benefit of activity restriction....

  10. Condom availability in high risk places and condom use

    DEFF Research Database (Denmark)

    Sandøy, Ingvild Fossgard; Blystad, Astrid; Shayo, Elizabeth H.

    2012-01-01

    study findings indicate that substantial further efforts should be made to secure that condoms are easily accessible in places where sexual relationships are initiated. Although condom distribution in drinking places has been pinpointed in the HIV/AIDS prevention strategies of all the three countries......Background A number of studies from countries with severe HIV epidemics have found gaps in condom availability, even in places where there is a substantial potential for HIV transmission. Although reported condom use has increased in many African countries, there are often big differences...... in the availability of condoms in places where people meet new sexual partners in these three African districts. Considering that previous studies have found that improved condom availability and accessibility in high risk places have a potential to increase condom use among people with multiple partners, the present...

  11. High-Risk Driving Behaviors among Adolescent Binge-Drinkers

    Science.gov (United States)

    Marcotte, Thomas D.; Bekman, Nicole M.; Meyer, Rachel A.; Brown, Sandra A.

    2013-01-01

    Background Binge drinking is common among adolescents. Alcohol use, and binge-drinking in particular, has been associated with neurocognitive deficits as well as risk-taking behaviors, which may contribute to negative driving outcomes among adolescents even while sober. Objectives To examine differences in self-reported driving behaviors between adolescent binge-drinkers and a matched sample of controls, including (a) compliance with graduated licensing laws, (b) high risk driving behaviors, and (c) driving outcomes (crashes, traffic tickets). Methods The present study examined driving behaviors and outcomes in adolescent recent binge drinkers (n=21) and demographically and driving history matched controls (n=17), ages 16-18. Results Binge drinkers more frequently violated graduated licensing laws (e.g., driving late at night), and engaged in more “high risk” driving behaviors, such as speeding and using a cell-phone while driving. Binge drinkers had more traffic tickets, crashes and “near crashes” than the control group. In a multivariate analysis, binge drinker status and speeding were the most robust predictors of a crash. Conclusion Binge drinking teens consistently engage in more dangerous driving behaviors and experience more frequent crashes and traffic tickets. They are also less compliant with preventative restrictions placed on youth while they are learning critical safe driving skills. Scientific Significance These findings highlight a need to examine the contribution of underlying traits (such as sensation seeking) and binge-related cognitive changes to these high-risk driving behaviors, which may assist researchers in establishing alternative prevention and policy efforts targeting this population. PMID:22324748

  12. [High risk factors of upper gastrointestinal bleeding after neurosurgical procedures].

    Science.gov (United States)

    Zheng, Kang; Wu, Gang; Cheng, Neng-neng; Yao, Cheng-jun; Zhou, Liang-fu

    2005-12-21

    To analyze high risk factors of postoperative upper gastrointestinal (GI) bleeding after neurosurgery so as to give guidance for prevention of GI bleeding. A questionnaire was developed to investigate the medical records of 1500 patients who were hospitalized and underwent neurosurgical operations in 1997. Logistic regression analysis was made. 1430 valid questionnaires were obtained. Postoperative upper GI bleeding occurred in 75 patients (5.24%). The incidence of upper GI bleeding were 6.64% (54/813) in the male patients and 3.40% (21/617) in the female persons (P = 0.007); 9.88% (41/415) in those aged > 50 and 3.35% in those aged hematoma, intraventricular hemorrhage, subdural hematoma, and extradural hematoma were 15.7%, 10.0%, 6.00%, and 2.94% respectively (P = 0.02). The incidence of upper GI bleeding of the patients with tumors of fourth ventricle of cerebrum, brainstem, cerebral hemisphere, and sellar hypothalamus were 15.79% (3/19), 7.89%, 5.71%, and 3.74% respectively. In the emergent cases, the incidence of upper GI bleeding was higher in those with hypertension. The incidence of upper GI bleeding was 5.46% in the patients undergoing adrenocortical hormone treatment, significantly higher than that in those who did not receive such treatment (2.13%). Patients who are at high risk of developing postoperative upper GI bleeding including that: age greater than 50 years; male; Glasgow Coma Score less than 10 pre and post operation; The lesion was located in brain stem and forth ventricle; Hypertensive cerebral hemorrhage; Intracerebral and intraventricular hemorrhagic brain trauma; Postoperative pneumonia, brain edema, encephalic high pressure, pyogenic infection of the central nervous system and other postoperative complications. The mortality of patients with postoperative upper GI bleeding was evidently higher than that of the patients without postoperative upper GI bleeding.

  13. Variation in readmission expenditures after high-risk surgery.

    Science.gov (United States)

    Jacobs, Bruce L; He, Chang; Li, Benjamin Y; Helfand, Alex; Krishnan, Naveen; Borza, Tudor; Ghaferi, Amir A; Hollenbeck, Brent K; Helm, Jonathan E; Lavieri, Mariel S; Skolarus, Ted A

    2017-06-01

    The Hospital Readmissions Reduction Program reduces payments to hospitals with excess readmissions for three common medical conditions and recently extended its readmission program to surgical patients. We sought to investigate readmission intensity as measured by readmission cost for high-risk surgeries and examine predictors of higher readmission costs. We used the Healthcare Cost and Utilization Project's State Inpatient Database to perform a retrospective cohort study of patients undergoing major chest (aortic valve replacement, coronary artery bypass grafting, lung resection) and major abdominal (abdominal aortic aneurysm repair [open approach], cystectomy, esophagectomy, pancreatectomy) surgery in 2009 and 2010. We fit a multivariable logistic regression model with generalized estimation equations to examine patient and index admission factors associated with readmission costs. The 30-d readmission rate was 16% for major chest and 22% for major abdominal surgery (P readmission costs for both chest (odds ratio [OR]: 1.99; 95% confidence interval [CI]: 1.60-2.48) and abdominal surgeries (OR: 1.86; 95% CI: 1.24-2.78). Comorbidities, length of stay, and receipt of blood or imaging was associated with higher readmission costs for chest surgery patients. Readmission >3 wk after discharge was associated with lower costs among abdominal surgery patients. Readmissions after high-risk surgery are common, affecting about one in six patients. Predictors of higher readmission costs differ among major chest and abdominal surgeries. Better identifying patients susceptible to higher readmission costs may inform future interventions to either reduce the intensity of these readmissions or eliminate them altogether. Copyright © 2017 Elsevier Inc. All rights reserved.

  14. High-risk sexual behavior among drug-using men.

    Science.gov (United States)

    Seidman, S N; Sterk-Elifson, C; Aral, S O

    1994-01-01

    Drug-using men are at high risk for acquisition and transmission of STD, presumably due to the risky behaviors practiced in environments of drug use. To study behaviors associated with STD transmission among drug-using men. Drug outreach workers distributed vouchers to self-identified drug-using men in urban Atlanta. Vouchers could be redeemed for cash at a storefront clinic where subjects provided urine for a urethritis screening test (leukocyte esterase test) and a drug screen, and were interviewed. Of 382 voucher recipients, 252 (66%) came to the clinic. Subjects were predominantly black (92%), homeless (70%), and aged 20 to 40 (88%). All used illicit drugs; none were currently receiving drug abuse treatment. Urine drug screen confirmed recent cocaine use in 63%, and recent opiate use in 4%. Three-fourths reported a history of STD, mostly gonorrhea. In the preceding 3 months, 14% had not had sex, 80% had sex exclusively with women, 4% had sex with both men and women, and 2% had sex exclusively with men. Of the heterosexually active men, 29% had 5 or more recent partners. Compared to other heterosexually active men, these men were more likely to always use alcohol or crack before having sex (prevalence ratio [PR] = 2.0, 95% CI = 1.3-2.5) and to drink alcohol every day (PR = 2.0, 95% CI = 1.2-3.3). Daily crack use was associated with choosing partners at elevated STD risk; daily alcohol use with having more partners. Positive drug screen for cocaine was associated with self-reported crack use. Urethritis, detected in 16%, was not correlated with behavior. A substantial number of drug-using men practice high-risk sexual behavior and should be targeted for intervention. Monetary and other incentives should be considered for recruitment. Further study is needed to clarify the relationship between sexual behavior, cocaine use, and STD.

  15. Pre-Irradiation Chemotherapy in High Risk Medulloblastoma

    International Nuclear Information System (INIS)

    Abd-El-Aal, H.

    2006-01-01

    Rationale: The present study evaluates the effect of pre-irradiation chemotherapy in pediatric patients with high risk medulloblastoma. Twenty-four (24) pediatric patients attended the pediatric unit of Kasr-EI-Aini Center of Radiation Oncology and Nuclear Medicine (NEMROCK) from January 2000 to January 2003. Patients and Methods: Our patients were 13 boys and II girls aged 3-12 years with a median of 6.5 years. According to Chang staging system 6 cases had T2, 14 cases had T3 A and 4 cases had T3 B, 20 cases were M0, 3 cases were M I and I case was M2. All patients were treated by initial surgery, 2 cycles of pre-irradiation chemotherapy followed by craniospinal radiation then by 4 cycles of post-radiation chemotherapy. Results: Fifteen out of the 20 patients with M0 had objective response (10CR + 5PR) and no one had disease progression after pre-irradiation chemotherapy. Among 4 patients with M0 disease, 2 patients had PR and 2 had S.D. There was no disease progression among patients who received pre-irradiation chemotherapy. The 3-year overall survival and 3-year progression-free survival; (PFS) were 50% and 51 %, respectively, Myelosuppression was the main toxic effect observed during pre-irradiation chemotherapy; however, there was no delay or interruption of craniospinal irradiation. Conclusion: Pre-irradiation chemotherapy is effective in high risk medulloblastoma and is associated with acceptable side effects. The delay in craniospinal irradiation (CSI) for about 5 weeks to receive 2 courses of chemotherapy will not significantly increase disease progression. Multiple cycles of post-irradiation chemotherapy can be given safely after C51. A larger number of patients and longer follow-up is needed to confirm the results

  16. Comparison of polysomnographic data in age-, sex- and Axis I psychiatric diagnosis matched HIV-seropositive and HIV-seronegative insomnia patients.

    Science.gov (United States)

    Low, Yinghui; Goforth, Harold W; Omonuwa, Toma; Preud'homme, Xavier; Edinger, Jack; Krystal, Andrew

    2012-12-01

    There is a high prevalence of insomnia in HIV-seropositive patients. Insomnia is associated with poorer disease outcomes, cognitive impairment and HIV-associated dementia. However there is limited data characterizing the type of sleep disturbances, and the cause. Previous studies report conflicting results, and observed changes in the distribution of REM and SWS were hypothesized to result from co-morbid mood disorders, although this is not established. We carried out this study to determine if there are differences in polysomnographic (PSG) sleep data in age-, sex- and Axis I diagnoses- matched HIV-seropositive and HIV-seronegative patients. Eighteen HIV-seropositive insomniacs were matched to HIV-seronegative insomniacs based on age, sex and Axis I diagnoses. Participants spent 2 consecutive nights in a sleep lab recording of PSG data. Multivariate analysis revealed an overall significant match-by-variable interaction (p=0.0126). Follow-up analysis show that compared to HIV-seronegative insomnia controls, HIV-seropositive insomniacs have significantly longer SOL, 8% decreased sleep efficiency, and 8-10% decreased time spent in REM sleep (p'saccounting for differences in age, sex and psychiatric diagnoses, HIV-seropositive patients with insomnia have significantly worse sleep than HIV-seronegative patients with insomnia. Unlike what previous authors have proposed, our results do not support the view that comorbid psychiatric disorders like depression are responsible for the observed differences in PSG findings and the greater incidence of insomnia, in HIV-seropositive patients when compared with other groups of insomnia patients. This suggests the presence of other etiologies including neuronal damage, psychosocial stressors, or comorbid medical conditions. Further studies are needed to determine the extent to which these play a role in insomnia in the HIV-seropositive population. Copyright © 2012 International Federation of Clinical Neurophysiology. Published by

  17. Clinical manifestations of antiphospholipid syndrome (APS) with and without antiphospholipid antibodies (the so-called 'seronegative APS').

    Science.gov (United States)

    Rodriguez-Garcia, Jose Luis; Bertolaccini, Maria Laura; Cuadrado, Maria Jose; Sanna, Giovanni; Ateka-Barrutia, Oier; Khamashta, Munther A

    2012-02-01

    Although the medical literature currently provides a growing number of isolated case reports of patients with clinically well-defined antiphospholipid syndrome (APS) and persistently negative antiphospholipid antibodies (aPL), there are no studies including a series of patients addressing the clinical features of this condition. The authors assessed clinical manifestations of APS in 154 patients: 87 patients with seropositive APS and 67 patients with thrombosis and/or pregnancy morbidity persistently negative for aPL and presenting with at least two additional non-criteria manifestations of APS (the so-called 'seronegative APS', SN-APS). Patients were interviewed at the time of recruitment, and a retrospective file review was carried out. There were no significant differences in the frequency of thrombotic events or obstetric morbidity in patients with SN-APS versus patients with seropositive APS: deep vein thrombosis (31.4% vs 31.0%), pulmonary embolism (23.8% vs 28.7%), stroke (14.9% vs 17.2%), transient ischaemic attack (11.9% vs 10.3%), early spontaneous abortions (67.1% vs 52.1%), stillbirths (62.5% vs 59.4%), prematurity (28.1% vs 21.7%) or pre-eclampsia (28.1% vs 23.1%). Classic and SN-APS patients show similar clinical profiles. The results suggest that clinical management in patients with APS should not be based only on the presence of conventional aPL.

  18. 2017 Taiwan lipid guidelines for high risk patients

    Directory of Open Access Journals (Sweden)

    Yi-Heng Li

    2017-04-01

    lowering therapies, adjunctive treatment with mipomersen, lomitapide, or PCSK9 inhibitors become necessary to further reduce LDL-C in patients with FH. Overall, these recommendations are to help the health care professionals in Taiwan to treat hyperlipidemia with current scientific evidences. We hope the prescription rate of lipid lowering drugs and control rate of hyperlipidemia in high risk patients could be increased by implementation of the clinical guidelines. The major purpose is to improve clinical outcomes of these high risk patients through the control of hyperlipidemia.

  19. High risk pregnancies and factors associated with neonatal death.

    Science.gov (United States)

    Demitto, Marcela de Oliveira; Gravena, Angela Andréia França; Dell'Agnolo, Cátia Millene; Antunes, Marcos Benatti; Pelloso, Sandra Marisa

    2017-04-03

    To identify the factors associated with intra-hospital neonatal mortality based on the individual characteristics of at-risk pregnant mothers, delivery and newborns. This was a cross-sectional epidemiological study of live newborns delivered by women attended at the high-risk outpatient unit of a philanthropic hospital in Maringá, Paraná, Brazil between September 2012 and September 2013. Six hundred and eighty-eight women participated in the study. The neonatal mortality coefficient found was 17.7/1,000 live births, most in the early neonatal phase. Premature labor, fetal malformation and multiple gestations were associated with neonatal death. Premature, very low birth weight newborns and those with an Apgar score of less than seven, five minutes after birth were at high risk of death. Identifying risk factors can help plan actions to consolidate the perinatal network. Specific programs should be incentivized in other countries, in the search for significant perinatal results such as reducing neonatal mortality. Identificar os fatores associados à mortalidade neonatal intra-hospitalar com base nas características individuais de gestantes de risco, do parto e do recém-nascido. Estudo epidemiológico do tipo transversal, realizado com crianças nascidas vivas de partos hospitalares de mulheres acompanhadas pelo ambulatório de alto risco de um hospital filantrópico de Maringá, Paraná, Brasil, no período de setembro de 2012 a setembro de 2013.RESULTADOS Fizeram parte da pesquisa 688 mulheres. O coeficiente de mortalidade neonatal foi de 17,7 óbitos/1.000 nascidos vivos, sendo sua maioria no período neonatal precoce. Trabalho de parto prematuro, malformação fetal e gestação múltipla foram as intercorrências associadas ao óbito neonatal. Recém-nascidos prematuros, com muito baixo peso ao nascer e Índice de Apgar menor que sete no quinto minuto de vida apresentaram risco elevado de morte. A identificação de fatores de risco pode auxiliar no

  20. From the lab - Predicting Autism in High-Risk Infants | NIH MedlinePlus the Magazine

    Science.gov (United States)

    ... High-Risk Infants Follow us Photo: iStock Predicting Autism in High-Risk Infants AN NIH-SUPPORTED STUDY ... high-risk, 6-month-old infants will develop autism spectrum disorder by age 2. Such a tool ...

  1. Fractional laser-mediated photodynamic therapy of high-risk basal cell carcinomas

    DEFF Research Database (Denmark)

    Haak, C S; Togsverd-Bo, K; Thaysen-Petersen, D

    2015-01-01

    efficacy and safety of AFXL-mediated PDT (AFXL-PDT) compared with conventional PDT of high-risk nBCC. METHODS: Patients with histologically verified facial nBCC (n = 32) defined as high-risk tumours were included; diameter > 15 mm, tumours located in high-risk zones, or on severely sun-damaged skin...

  2. The Problem of Homosexuality: Desire-in-Uneasiness, Friendship, Family, Freedom

    Directory of Open Access Journals (Sweden)

    Brian Bergen-Aurand

    2016-02-01

    Full Text Available Zenne Dancer is a 2011 Turkish film written by Caner Alper and directed by Alper and Mehmet Binay. It is inspired by the story of Ahmet Yildiz, a gay Kurdish Turk allegedly murdered by his father in 2008 for dishonoring his family. Through its depiction of the unlikely friendship between three men, the film addresses the problem of homosexuality, the desire-in-uneasiness evoked by men being together, and the complex social structures of honor killings. In its address of honor killings, Zenne Dancer follows in a prestigious line of some of the best of Turkish and world cinema. Importantly, though, there are differences here as Zenne Dancer reimagines the relationships involved in crimes of honor. First, Zenne Dancer deploys the story of a father killing his son, rather than his daughter, to save the family honor, which is threatened by homosexual desire rather than the loss of virginity or illegitimate pregnancy. Second, rather than pitting the modern state against religion, tradition, or pre-modern culture, Zenne Dancer’s critique of honor killing implicates both the police and the military in the violence done in the name of tradition (not religion. Islam plays a much smaller part than economic deprivation or the trauma of war in this film. Third, the film complicates gendered expectations through its deployment of female characters—mothers, sisters, lovers—who all have their own relationships with and perspectives on these men. The film depicts heteropatriarchy as a system harmful to women and men and shows men and women enforcing and resisting that harm. In the end, Zenne Dancer connects these thematic concerns through a mixture of realist story, dance video, daydream, fairytale, and melodrama in a film ultimately concerned with the care of the self and the meaning of liberation. Thus, it resists falling into fictional “realist anthropology” or simplistic assertions of repression in confronting the complexities of honor killings

  3. Attitudes toward homosexuality among young adults: connections to gender role identity, gender-typed activities, and religiosity.

    Science.gov (United States)

    Harbaugh, Evan; Lindsey, Eric W

    2015-01-01

    Individual differences in attitudes toward homosexuality have been linked to numerous personality and demographic variables. This study investigated the influence that gender role identity, involvement in gender-typed activities, and religiosity plays in this relationship. The sample included 194 undergraduate students from a Northeastern university. Analyses revealed that both males and females who held a more masculine gender role identity and individual commitment to religion scored higher on measures of homophobia and heteronormativity, whereas there was no association between spiritual meaning in life and attitudes toward homosexuality. Among males, but not females, more masculine gender identity and less spiritual meaning in life was associated with greater homophobia. The importance of the findings for research on the origins of attitudes toward individuals with a homosexual orientation are discussed, as well as the potential directions for future research on connections between gender role identity, religious affiliation, and attitudes toward gays and lesbians.

  4. Influence of gender role orientation (masculinity versus femininity) on body satisfaction and eating attitudes in homosexuals, heterosexuals and transsexuals.

    Science.gov (United States)

    Cella, Stefania; Iannaccone, Mara; Cotrufo, Paolo

    2013-06-01

    The primary aim of this study was to investigate the relationship between gender role orientation and eating disorder attitudes and behaviors and body dissatisfaction in a sample of homosexuals, heterosexuals, and transsexuals. We screened 132 homosexuals, 178 heterosexuals (both male and female), and 15 MtF transsexuals by means of an ad hoc socio-demographic schedule; the Eating Disorders Inventory-2 and Symptom Checklist; the Body Uneasiness Test and the Bem Sex Role Inventory. Differences between homosexual, heterosexual, and transsexual participants emerged, but those data seem to be best explained by the constructs of femininity and masculinity than by the biological gender. The empirical evidence of a positive correlation between femininity and eating problems, and the negative correlation between masculinity and eating problems, is full of implications. Eating disorders appear to be diseases of femininity; masculinity seems to be a protective factor, independently by the biological gender.

  5. The economics of sexuality: the effect of HIV/AIDS on homosexual behavior in the United States.

    Science.gov (United States)

    Francis, Andrew M

    2008-05-01

    In this paper, I test a simple microeconomic theory of sexuality. I apply the theory to make predictions about the effect of AIDS on sexuality, since AIDS dramatically altered the cost of sexual activities. Using a nationally representative dataset on sexuality in the United States, I estimate the effect of AIDS on male and female homosexual behavior. To do so, I postulate that people who have a relative with AIDS, on average, have more knowledge, awareness, and fear of AIDS. Empirically, this variable is uncorrelated with a number of individual background characteristics. I present evidence that AIDS causes some men to shift from homosexual to heterosexual behavior, whereas AIDS causes some women to shift from heterosexual to homosexual behavior. Thus, sexual behavior may respond to incentives. I consider alternative hypotheses, including biological theories of sexual orientation and stigma-related survey bias, and argue that they are unlikely to explain the results.

  6. Homosexuals Who Indulge in Excessive Use of Alcohol and Drugs: Psychosocial Factors to be Taken into Account by Community and Intervention Workers.

    Science.gov (United States)

    Israelstam, Stephen; Lambert, Sylvia

    1989-01-01

    Asserts that secluded nature of homosexual bar and its importance as social center is one example of how lifestyle may contribute to alcohol and drug problems of homosexuals. Describes what aspects of lifestyle and social control must be taken into account when intervening into such problems. (Author)

  7. Public endorsement of restrictions on three aspects of free expression by homosexuals: socio-demographic and trends analysis 1973-1988.

    Science.gov (United States)

    Dejowski, E F

    1992-01-01

    The willingness of the public to endorse proposals to remove gay-positive books from library shelves, to dismiss college teachers who are homosexuals, and to prohibit public speaking by homosexuals was examined. A socio-demographic analysis aggregating the entire period 1973 through 1988, and an analysis of trends over the period, were undertaken using data from the General Social Surveys. Responses to survey questions concerning homosexuals were compared with responses to similar questions concerning other unpopular groups, and to questions which called upon the respondent to make a moral judgment concerning homosexual relations. A significant decline over the period was found in the public's willingness to endorse restrictions on homosexuals, and on each of the other unpopular groups used for comparison. Level of education appeared to be a strong indicator of a more tolerant attitude. Paradoxically, negative moral attitudes toward homosexual relations did not decline. Bias in the wording of the General Social Surveys' questions concerning the moral dimension of homosexuality may have distorted these results, however. The public's moral attitude toward homosexual behavior does appear to be quite labile from year to year, suggesting that concerted efforts to educate the public on this subject can have an important and rapid effect.

  8. La institución matrimonial después del matrimonio homosexual

    OpenAIRE

    Beatriz Gimeno; Violeta Barrientos

    2009-01-01

    Este artículo sostiene la idea de que el reconocimiento del matrimonio homosexual –frente a otro tipo de iniciativas–, conseguido por el movimiento LGTB español en ese país, constituye una reforma no reformista. Es decir, antes que una reivindicación conservadora, que actualiza los sentidos naturalizados en el matrimonio al imponerlos a nuevos sujetos (homosexuales), constituye un mecanismo hacia su des-institucionalización. Se trataría de una reivindicación que al tiempo que afirma la plena...

  9. Mediální obraz homosexuality v Korejské republice

    OpenAIRE

    Vildová, Marie

    2017-01-01

    The aim of this thesis is to present the image of homosexuality in Korean media, especially during of years 2000-2015. First of all, it aims to introduce the general mood and prejudice against sexuality caused by the Korean conservative society. This paper will introduce the roots of this hostility and explain the reasons that formed this general view of the sexual minorities in South Korea. Also, another main focal point of this paper is to offer insight into South Korean media culture, wher...

  10. Education and School Physical Homosexuality: a dialogue on the methodological tract

    Directory of Open Access Journals (Sweden)

    Aline Gomes Machado

    2016-09-01

    Full Text Available This study has as purpose toestablishreflectionsabout the presence ofhomosexuals inhigh schoolphysical education classes,trying to understand how the physical education teachers develop their pedagogical actions to deal with sexual diversity, realty increasingly seen in the school world. It isan exploratoryresearch with qualitative approach, wherewe used thesemi-structured questionnaire as a data procedure. The results showed a silencing, a denial of homosexuals students by the teachers of that discipline. As an outcome, there is a potentiating of heteronormative power structure, what contributes to the maintenance of discrimination and prejudice values,  causing  weakness in school`s  transforming power.

  11. [Doctor and poet as rivals. Sigmund Freud, Alfred von Berger and the narrative of female homosexuality].

    Science.gov (United States)

    Goldmann, Stefan

    2011-01-01

    Starting from a passage in the Dora case history where Freud suggests some differences between a literary and a clinical narrative of female homosexuality, this paper presents examples which he might have had in mind. Besides Balzac's "La fille aux yeux d'or" (1834/35) it is in particular Alfred v. Berger's novella "Die Italienerin [The Italian woman]" (1904) which may have served as a model and counterpoint to the literary strategies used in Freud's case history. Freud had a relationship of long standing with Berger. This newly discovered source may provide a clue for the date at which Freud finalized the Dora manscript which he had held back for years.

  12. Contesting Sexual Morality. Futurism, Masculinity, and Homosexuality in Florence, 1913-1914

    Directory of Open Access Journals (Sweden)

    Mauro Pasqualini

    2013-10-01

    Full Text Available The article seeks to contribute to studies on gender and sexuality among Italian avant-gardes by focusing on the Florentine Futurist journal Lacerba (1913-1915. It argues that the journal sustained a provocative campaign against conventional sexual morality, which included a vindication of sexual diversity and homosexuality. Through the writings of contributors such as Italo Tavolato and Giovanni Papini, Lacerba combined Futurist rhetoric with an elitist, iconoclastic, and irreverent conception of sexuality. The article concludes that Lacerba’s campaign to sexual reform was severely curtailed by the authors’ nationalism.

  13. Preferred and Actual Relative Height among Homosexual Male Partners Vary with Preferred Dominance and Sex Role

    OpenAIRE

    Valentova, Jaroslava Varella; Stulp, Gert; Třebický, Vít; Havlíček, Jan

    2014-01-01

    Previous research has shown repeatedly that human stature influences mate preferences and mate choice in heterosexuals. In general, it has been shown that tall men and average height women are most preferred by the opposite sex, and that both sexes prefer to be in a relationship where the man is taller than the woman. However, little is known about such partner preferences in homosexual individuals. Based on an online survey of a large sample of non-heterosexual men (N = 541), we found that t...

  14. The Narrative Analysis of the Discourse on Homosexual BDSM Pornograhic Video Clips of The Manhunt Variety

    Directory of Open Access Journals (Sweden)

    Milica Vasić

    2016-02-01

    Full Text Available In this paper we have analyzed the ideal-type model of the story which represents the basic framework of action in Manhunt category pornographic internet video clips, using narrative analysis methods of Claude Bremond. The results have shown that it is possible to apply the theoretical model to elements of visual and mass culture, with certain modifications and taking into account the wider context of the narrative itself. The narrative analysis indicated the significance of researching categories of pornography on the internet, because it leads to a deep analysis of the distribution of power in relations between the categories of heterosexual and homosexual within a virtual environment.

  15. The birth of modern criminology and gendered constructions of homosexual criminal identity.

    Science.gov (United States)

    Woods, Jordan Blair

    2015-01-01

    There is a dearth of engagement with LGBTQ populations, and sexual orientation and gender identity more broadly, in the field of criminology. This article analyzes the treatment of sexual orientation and gender identity at the birth of the discipline around the 1870 s. Through an analysis of Cesare Lombroso's writings, the article argues that a multifaceted stigma of deviance attached to homosexuality and gender nonconformity in early criminological theory. The article explains this multifaceted stigma in terms of broader political, social, cultural, and legal developments before and during the late nineteenth century that shaped modern Western conceptions of sexual orientation and gender identity.

  16. La reconstrucción del cuerpo homosexual en los tiempos del SIDA

    Directory of Open Access Journals (Sweden)

    RICARDO LLAMAS

    1994-01-01

    Full Text Available Este trabajo pretende revisar los procesos generales de reducción de categorías humanas a un estatuto corporeo, prestando especial atención al proceso histórico de constitución de un "cuerpo homosexual" y a la violenta reorganización de tales postulados en el actual contexto de la pandemia de sida. De forma aparentemente paradójica, propondré que es desde el cuerpo desde donde debe lucharse, tanto contra los criterios de reducción discriminatoria y dominación como contra la mismisima pandemia.

  17. Men at risk; a qualitative study on HIV risk, gender identity and violence among men who have sex with men who report high risk behavior in Kampala, Uganda.

    Science.gov (United States)

    King, Rachel; Barker, Joseph; Nakayiwa, Sylvia; Katuntu, David; Lubwama, George; Bagenda, Danstan; Lane, Tim; Opio, Alex; Hladik, Wolfgang

    2013-01-01

    In Uganda, men who have sex with men (MSM) are at high risk for HIV. Between May 2008 and February 2009 in Kampala, Uganda, we used respondent driven sampling (RDS) to recruit 295 MSM≥18 years who reported having had sex with another man in the preceding three months. The parent study conducted HIV and STI testing and collected demographic and HIV-related behavioral data through audio computer-assisted self-administered interviews. We conducted a nested qualitative sub-study with 16 men purposively sampled from among the survey participants based on responses to behavioral variables indicating higher risk for HIV infection. Sub-study participants were interviewed face-to-face. Domains of inquiry included sexual orientation, gender identity, condom use, stigma, discrimination, violence and health seeking behavior. Emergent themes included a description of sexual orientation/gender identity categories. All groups of men described conflicting feelings related to their sexual orientation and contextual issues that do not accept same-sex identities or behaviors and non-normative gender presentation. The emerging domains for facilitating condom use included: lack of trust in partner and fear of HIV infection. We discuss themes in the context of social and policy issues surrounding homosexuality and HIV prevention in Uganda that directly affect men's lives, risk and health-promoting behaviors.

  18. Men at risk; a qualitative study on HIV risk, gender identity and violence among men who have sex with men who report high risk behavior in Kampala, Uganda.

    Directory of Open Access Journals (Sweden)

    Rachel King

    Full Text Available In Uganda, men who have sex with men (MSM are at high risk for HIV. Between May 2008 and February 2009 in Kampala, Uganda, we used respondent driven sampling (RDS to recruit 295 MSM≥18 years who reported having had sex with another man in the preceding three months. The parent study conducted HIV and STI testing and collected demographic and HIV-related behavioral data through audio computer-assisted self-administered interviews. We conducted a nested qualitative sub-study with 16 men purposively sampled from among the survey participants based on responses to behavioral variables indicating higher risk for HIV infection. Sub-study participants were interviewed face-to-face. Domains of inquiry included sexual orientation, gender identity, condom use, stigma, discrimination, violence and health seeking behavior. Emergent themes included a description of sexual orientation/gender identity categories. All groups of men described conflicting feelings related to their sexual orientation and contextual issues that do not accept same-sex identities or behaviors and non-normative gender presentation. The emerging domains for facilitating condom use included: lack of trust in partner and fear of HIV infection. We discuss themes in the context of social and policy issues surrounding homosexuality and HIV prevention in Uganda that directly affect men's lives, risk and health-promoting behaviors.

  19. Pressure ulcer prevention in high-risk postoperative cardiovascular patients.

    Science.gov (United States)

    Jackson, Melissa; McKenney, Teresa; Drumm, Jennifer; Merrick, Brian; LeMaster, Tamara; VanGilder, Catherine

    2011-08-01

    Little has been published about how to prevent pressure ulcers in severely debilitated, immobile patients in intensive care units. To present a possible prevention strategy for postoperative cardiovascular surgery patients at high risk for development of pressure ulcers. Staff chose to implement air fluidized therapy beds, which provide maximal immersion and envelopment as a measure for preventing pressure ulcers in patients who (1) required vasopressors for at least 24 hours and (2) required mechanical ventilation for at least 24 hours postoperatively. Only 1 of 27 patients had a pressure ulcer develop while on the air fluidized therapy bed (February 2008 through August 2008), and that ulcer was only a stage I ulcer, compared with 40 ulcers in 25 patients before the intervention. Patients spent a mean of 7.9 days on the mattress, and the cost of bed rental was approximately $18000, which was similar to the cost of treatment of 1 pressure ulcer in stage III or IV (about $40000) and was considered cost-effective.

  20. INSTRUMENTS OF HIGH RISK SEXUAL BEHAVIOR ASSESSMENT: A SYSTEMATIC REVIEW.

    Science.gov (United States)

    Mirzaei, Mojtaba; Ahmadi, Khodabakhsh; Saadat, Seyed-Hassan; Ramezani, Mohammad Arash

    2016-02-01

    Sexual behavior is a complex activity affecting all aspects of human's life. Risky sexual behaviors impose negative outcomes on family, relationships and health. Unsafe sex is the second most leading cause of disability adjusted life years worldwide. Valid and reliable tools for assessment of risky sexual behaviors are necessary for implementing preventive measures. we searched Medline and the Cochrane Library of Systematic Reviews, with the keywords of "risky sexual behavior assessment", "sexual risk assessment", "high risk sexual behavior", "sexual risk taking". By reviewing references of the articles, some complementary studies were added. Assessment can be performed by questionnaire or non-questionnaire instruments. Questionnaires vary depending on their target population, evaluation of risky sexual behavior as a whole or focusing on an associated risk factor. In order to avoid usual biases in self reports, objective biomarker assessment of unprotected sex are employed. These markers include prostate specific antigen, chromosome Y DNA and Seminogelin. Risky sexual behavior can be assessed by various subjective and objective methods. While self-reports are more feasible, objective methods offer a higher degree of reliability. Further studies for finding more feasible methods of using biomarkers are recommended.

  1. High risk HPV testing following treatment for cervical intraepithelial neoplasia.

    Science.gov (United States)

    Molloy, M; Comer, R; Rogers, P; Dowling, M; Meskell, P; Asbury, K; O'Leary, M

    2016-11-01

    To determine the results of combined cytology and high-risk human papilloma virus (HR HPV) tests at 6 and 18 months postcolposcopy treatment at one Irish colposcopy centre. All women who attended the centre's colposcopy smear clinic for a co-test 6 months (initial test) posttreatment were included in the audit (n = 251). The results revealed negative HR HPV for 79 % (n = 198) of women tested 6 months after treatment and positive results for 21 % (n = 53). HR HPV testing was more sensitive than cytology and led to early detection of residual disease. No women with negative HR HPV had high-grade cytology. HR HPV is more sensitive than cytology for detection of persistent CIN. However, 19 women with positive HR HPV had normal colposcopy with no persistent CIN detected. A national cost-benefit analysis is recommended to determine the value of the second co-test.

  2. Patients who reattend after head injury: a high risk group.

    Science.gov (United States)

    Voss, M.; Knottenbelt, J. D.; Peden, M. M.

    1995-01-01

    OBJECTIVE--To assess risk factors for important neurosurgical effects in patients who reattend after head injury. DESIGN--Retrospective study. SUBJECTS--606 patients who reattended a trauma unit after minor head injury. MAIN OUTCOME MEASURES--Intracranial abnormality detected on computed tomography or the need for neurosurgical intervention. RESULTS--Five patients died: two from unrelated causes and three from raised intracranial pressure. On multiple regression analysis the only significant predictor for both abnormality on computed tomography (14.4% of reattenders) and the need for operation (5% of reattenders) was vault fracture seen on the skull radiograph (P personality change, and seizures were significantly associated only with abnormality on computed tomography. Headache, dizziness, nausea, and vomiting were common in reattenders but were found to have no independent significance. CONCLUSIONS--All patients who reattend after head injury should undergo computed tomography as at least 14% of scans can be expected to yield positive results. Where this facility is not available patients with predictors for operation should be urgently referred for neurosurgical opinion. Other patients can be readmitted and need referral only if symptoms persist despite symptomatic treatment or there is neurological deterioration while under observation. These patients are a high risk group and should be treated seriously. PMID:8520273

  3. High-risk bladder cancer: improving outcomes with perioperative chemotherapy

    Directory of Open Access Journals (Sweden)

    Daniel Y.C. Heng

    2011-12-01

    Full Text Available Despite treatment with radical cystectomy and pelvic lymph node dissection, muscle invasive bladder cancer has a relapse rate of 50%. Patients can develop regionally advanced or metastatic disease that ultimately leads to death. The addition of neoadjuvant or adjuvant chemotherapy to reduce the risk of relapse and death has been extensively studied over the past two decades. Two contemporary trials coupled with a recent meta-analysis evaluating neoadjuvant chemotherapy demonstrated a modest but real improvement in overall survival. This has made neoadjuvant chemotherapy a standard of care. Clinical trials evaluating adjuvant chemotherapy in patients with high-risk disease have been plagued with statistical flaws and have, therefore, been unable to define the survival impact of this approach. It is hoped that ongoing adjuvant trials that are powered to detect small but meaningful clinical differences will clarify the benefit of chemotherapy after cystectomy. Since there are theoretical advantages and disadvantages to each of these approaches, both are widely used in North America. The evidence behind each approach and potential future developments in this field will be described.

  4. Characteristics of violence among high-risk adolescent girls.

    Science.gov (United States)

    Secor-Turner, Molly; Garwick, Ann; Sieving, Renee; Seppelt, Ann

    2014-01-01

    Recent evidence demonstrates increasing rates of involvement with violence among adolescent girls. The objective of this study was to describe the types and sources of violence experienced within social contexts of adolescent girls at high risk for pregnancy. Qualitative data for this analysis are drawn from intervention summary reports of 116 girls participating in Prime Time, a youth development intervention for adolescent girls. Descriptive content analysis techniques were used to identify types and sources of violence experienced by girls within their daily contexts. Types of violence included physical fighting, witnessing violence, physical abuse, gang-related violence, verbal fighting, verbal abuse, and sexual abuse. Sources of violence included family, peers and friends, romantic partners, community violence, and self-perpetrated violence. Many girls in this study experienced violence in multiple contexts. It is imperative that efforts to assess and prevent violence among adolescent girls include paying attention to the social contexts in which these adolescents live. Copyright © 2014 National Association of Pediatric Nurse Practitioners. Published by Mosby, Inc. All rights reserved.

  5. The genetic landscape of high-risk neuroblastoma.

    Science.gov (United States)

    Pugh, Trevor J; Morozova, Olena; Attiyeh, Edward F; Asgharzadeh, Shahab; Wei, Jun S; Auclair, Daniel; Carter, Scott L; Cibulskis, Kristian; Hanna, Megan; Kiezun, Adam; Kim, Jaegil; Lawrence, Michael S; Lichenstein, Lee; McKenna, Aaron; Pedamallu, Chandra Sekhar; Ramos, Alex H; Shefler, Erica; Sivachenko, Andrey; Sougnez, Carrie; Stewart, Chip; Ally, Adrian; Birol, Inanc; Chiu, Readman; Corbett, Richard D; Hirst, Martin; Jackman, Shaun D; Kamoh, Baljit; Khodabakshi, Alireza Hadj; Krzywinski, Martin; Lo, Allan; Moore, Richard A; Mungall, Karen L; Qian, Jenny; Tam, Angela; Thiessen, Nina; Zhao, Yongjun; Cole, Kristina A; Diamond, Maura; Diskin, Sharon J; Mosse, Yael P; Wood, Andrew C; Ji, Lingyun; Sposto, Richard; Badgett, Thomas; London, Wendy B; Moyer, Yvonne; Gastier-Foster, Julie M; Smith, Malcolm A; Guidry Auvil, Jaime M; Gerhard, Daniela S; Hogarty, Michael D; Jones, Steven J M; Lander, Eric S; Gabriel, Stacey B; Getz, Gad; Seeger, Robert C; Khan, Javed; Marra, Marco A; Meyerson, Matthew; Maris, John M

    2013-03-01

    Neuroblastoma is a malignancy of the developing sympathetic nervous system that often presents with widespread metastatic disease, resulting in survival rates of less than 50%. To determine the spectrum of somatic mutation in high-risk neuroblastoma, we studied 240 affected individuals (cases) using a combination of whole-exome, genome and transcriptome sequencing as part of the Therapeutically Applicable Research to Generate Effective Treatments (TARGET) initiative. Here we report a low median exonic mutation frequency of 0.60 per Mb (0.48 nonsilent) and notably few recurrently mutated genes in these tumors. Genes with significant somatic mutation frequencies included ALK (9.2% of cases), PTPN11 (2.9%), ATRX (2.5%, and an additional 7.1% had focal deletions), MYCN (1.7%, causing a recurrent p.Pro44Leu alteration) and NRAS (0.83%). Rare, potentially pathogenic germline variants were significantly enriched in ALK, CHEK2, PINK1 and BARD1. The relative paucity of recurrent somatic mutations in neuroblastoma challenges current therapeutic strategies that rely on frequently altered oncogenic drivers.

  6. The genetic landscape of high-risk neuroblastoma

    Science.gov (United States)

    Pugh, Trevor J.; Morozova, Olena; Attiyeh, Edward F.; Asgharzadeh, Shahab; Wei, Jun S.; Auclair, Daniel; Carter, Scott L.; Cibulskis, Kristian; Hanna, Megan; Kiezun, Adam; Kim, Jaegil; Lawrence, Michael S.; Lichenstein, Lee; McKenna, Aaron; Pedamallu, Chandra Sekhar; Ramos, Alex H.; Shefler, Erica; Sivachenko, Andrey; Sougnez, Carrie; Stewart, Chip; Ally, Adrian; Birol, Inanc; Chiu, Readman; Corbett, Richard D.; Hirst, Martin; Jackman, Shaun D.; Kamoh, Baljit; Khodabakshi, Alireza Hadj; Krzywinski, Martin; Lo, Allan; Moore, Richard A.; Mungall, Karen L.; Qian, Jenny; Tam, Angela; Thiessen, Nina; Zhao, Yongjun; Cole, Kristina A.; Diamond, Maura; Diskin, Sharon J.; Mosse, Yael P.; Wood, Andrew C.; Ji, Lingyun; Sposto, Richard; Badgett, Thomas; London, Wendy B.; Moyer, Yvonne; Gastier-Foster, Julie M.; Smith, Malcolm A.; Auvil, Jaime M. Guidry; Gerhard, Daniela S.; Hogarty, Michael D.; Jones, Steven J. M.; Lander, Eric S.; Gabriel, Stacey B.; Getz, Gad; Seeger, Robert C.; Khan, Javed; Marra, Marco A.; Meyerson, Matthew; Maris, John M.

    2013-01-01

    Neuroblastoma is a malignancy of the developing sympathetic nervous system that often presents with widespread metastatic disease, resulting in survival rates of less than 50%1. To determine the spectrum of somatic mutation in high-risk neuroblastoma, we studied 240 cases using a combination of whole exome, genome and transcriptome sequencing as part of the Therapeutically Applicable Research to Generate Effective Treatments (TARGET) initiative. Here we report a low median exonic mutation frequency of 0.60 per megabase (0.48 non-silent), and remarkably few recurrently mutated genes in these tumors. Genes with significant somatic mutation frequencies included ALK (9.2% of cases), PTPN11 (2.9%), ATRX (2.5%, an additional 7.1% had focal deletions), MYCN (1.7%, a recurrent p.Pro44Leu alteration), and NRAS (0.83%). Rare, potentially pathogenic germline variants were significantly enriched in ALK, CHEK2, PINK1, and BARD1. The relative paucity of recurrent somatic mutations in neuroblastoma challenges current therapeutic strategies reliant upon frequently altered oncogenic drivers. PMID:23334666

  7. Prediabetes: a high-risk state for diabetes development.

    Science.gov (United States)

    Tabák, Adam G; Herder, Christian; Rathmann, Wolfgang; Brunner, Eric J; Kivimäki, Mika

    2012-06-16

    Prediabetes (intermediate hyperglycaemia) is a high-risk state for diabetes that is defined by glycaemic variables that are higher than normal, but lower than diabetes thresholds. 5-10% of people per year with prediabetes will progress to diabetes, with the same proportion converting back to normoglycaemia. Prevalence of prediabetes is increasing worldwide and experts have projected that more than 470 million people will have prediabetes by 2030. Prediabetes is associated with the simultaneous presence of insulin resistance and β-cell dysfunction-abnormalities that start before glucose changes are detectable. Observational evidence shows associations between prediabetes and early forms of nephropathy, chronic kidney disease, small fibre neuropathy, diabetic retinopathy, and increased risk of macrovascular disease. Multifactorial risk scores using non-invasive measures and blood-based metabolic traits, in addition to glycaemic values, could optimise estimation of diabetes risk. For prediabetic individuals, lifestyle modification is the cornerstone of diabetes prevention, with evidence of a 40-70% relative-risk reduction. Accumulating data also show potential benefits from pharmacotherapy. Copyright © 2012 Elsevier Ltd. All rights reserved.

  8. Prediabetes: A high-risk state for developing diabetes

    Science.gov (United States)

    Tabák, Adam G.; Herder, Christian; Rathmann, Wolfgang; Brunner, Eric J.; Kivimäki, Mika

    2013-01-01

    Summary Prediabetes (or “intermediate hyperglycaemia”), based on glycaemic parameters above normal but below diabetes thresholds is a high risk state for diabetes with an annualized conversion rate of 5%–10%; with similar proportion converting back to normoglycaemia. The prevalence of prediabetes is increasing worldwide and it is projected that >470 million people will have prediabetes in 2030. Prediabetes is associated with the simultaneous presence of insulin resistance and β-cell dysfunction, abnormalities that start before glucose changes are detectable. Observational evidence shows associations of prediabetes with early forms of nephropathy, chronic kidney disease, small fibre neuropathy, diabetic retinopathy, and increased risk of macrovascular disease. Multifactorial risk scores could optimize the estimation of diabetes risk using non-invasive parameters and blood-based metabolic traits in addition to glycaemic values. For prediabetic individuals, lifestyle modification is the cornerstone of diabetes prevention with evidence of a 40%–70% relative risk reduction. Accumulating data also suggests potential benefits from pharmacotherapy. PMID:22683128

  9. [Preservation of high risk fungal cultures of Histoplasma and Cryptococcus].

    Science.gov (United States)

    Fernández Andreu, C Carlos Manuel; Díaz Suárez, Luis Alberto; Ilnait Zaragozi, María Teresa; Aragonés López, Carlos; Martínez Machín, Gerardo; Perurena Lancha, Mayda R

    2012-01-01

    culture collections are responsible for providing the microbial resources for development of biological sciences. Storage in distilled water is one of the easiest and least expensive method for long-term fungal preservation. to evaluate the usefulness of this preservation method in fungal culture of Histoplasma and Cryptococcus. the preservation condition of the highest biological risk species from Histoplasma y Cryptococcus genera, included in the fungal culture collection of "Pedro Kouri" Institute of Tropical Medicine in Havana, was evaluated in this study. One hundred and two strains stored in distilled water, 92% of which had been preserved for more than 10 years, were analyzed. the percentages of recovered strains from H. capsulatum, C. neoformans and C. gattii were 64.3%; 79.1% and 100% respectively. This method of preservation proved to be satisfactory for fungal culture in labs with limited financial resources. A web-based database with interesting information about the collection was made. The importance of strict compliance with the biosafety measures in these collections, particularly with high risk pathogens. preservation of fungal cultures in distilled water is a very useful method for laboratories with limited resources. Culture collections should be assumed as an essential activity in order to solve increasing challenges in the development of biomedical sciences.

  10. Protecting military personnel from high risk dietary supplements.

    Science.gov (United States)

    Deuster, Patricia A; Lieberman, Harris R

    2016-01-01

    It is legal tomarketmost naturally occurring substances as dietary supplements in the USA without manufacturers demonstrating they are safe or effective, and an endless variety of ingredients, from esoteric botanicals to unapproved pharmaceuticals, can be found in dietary supplements. Use of certain supplements can pose a risk, but since a robust reporting systemdoes not exist in the USA it is difficult to know which are problematic and the number of adverse events (AE) resulting from their use. Certain populations, includingmilitary personnel, aremore likely to use dietary supplements than the general population. Approximately 70% of military personnel take dietary supplements while about 50% of civilians do. Service members prefer supplements purported to enhance physical performance such as supposedly natural stimulants, protein and amino acids, and combination products. Since some of thesemay be problematic, Servicemembers are probably at higher risk of injury than the general population. Ten percent of military populations appear to be taking potentially risky supplements, and the US Department of Defense (DoD) has taken variousmeasures to protect uniformed personnel including education, policy changes, and restricting sales. Actions taken include launching Operation Supplement Safety (OPSS), introducing a High Risk Supplement list, educating health care professionals on reporting AE thatmight be associated with dietary supplements, recommending policy for reporting AE, and developing an online AE reporting system. OPSS is a DoD-wide effort to educate service members, leaders, health care providers, military families, and retirees on how to safely select supplements

  11. High risk of postpartum relapses in neuromyelitis optica spectrum disorder.

    Science.gov (United States)

    Klawiter, Eric C; Bove, Riley; Elsone, Liene; Alvarez, Enrique; Borisow, Nadja; Cortez, Melissa; Mateen, Farrah; Mealy, Maureen A; Sorum, Jaime; Mutch, Kerry; Tobyne, Sean M; Ruprecht, Klemens; Buckle, Guy; Levy, Michael; Wingerchuk, Dean; Paul, Friedemann; Cross, Anne H; Jacobs, Anu; Chitnis, Tanuja; Weinshenker, Brian

    2017-11-28

    To study the effect of pregnancy on the frequency of neuromyelitis optica spectrum disorder (NMOSD) relapse and evaluate rates of pregnancy-related complications in an international multicenter setting. We administered a standardized survey to 217 women with NMOSD from 7 medical centers and reviewed their medical records. We compared the annualized relapse rate (ARR) during a baseline period 2 years prior to a participant's first pregnancy to that during pregnancy and to the 9 months postpartum. We also assessed pregnancy-related complications. There were 46 informative pregnancies following symptom onset in 31 women with NMOSD. Compared to baseline (0.17), ARR was increased both during pregnancy (0.44; p = 0.035) and during the postpartum period (0.69; p = 0.009). The highest ARR occurred during the first 3 months postpartum (ARR 1.33). A total of 8 of 76 (10.5%) with onset of NMOSD prior to age 40 experienced their initial symptom during the 3 months postpartum, 2.9 times higher than expected. The postpartum period is a particularly high-risk time for initial presentation of NMOSD. In contrast to published observations in multiple sclerosis, in neuromyelitis optica, relapse rate during pregnancy was also increased, although to a lesser extent than after delivery. © 2017 American Academy of Neurology.

  12. Ibn Ḥazm on Homosexuality. A case-study of Ẓāhirī legal Methodology

    OpenAIRE

    Adang, Camilla

    2003-01-01

    This article discusses the views of the teologian and legal scholar Ibn Ḥazm of Cordoba (d. 456/1064) on homosexuality. Although reference is made to his literary work Ṭawq al-ḥamāma, which is rich in anecdotes on homoerotic attraction, the article focuses on Ibn Ḥazm's multivolume legal tract Kitāb al-Muḥallā, a work written from a Ẓāhirī, or literalist perspective. A step-by-step analysis of Ibn Hazm's legal reasoning on homosexuality, both male (

  13. Familial aggregation of arthritis-related diseases in seropositive and seronegative rheumatoid arthritis: a register-based case-control study in Sweden.

    Science.gov (United States)

    Frisell, Thomas; Hellgren, Karin; Alfredsson, Lars; Raychaudhuri, Soumya; Klareskog, Lars; Askling, Johan

    2016-01-01

    Our objective was to estimate the risk of developing rheumatoid arthritis (RA) associated with a family history of non-RA arthritis-related diseases. This familial co-aggregation is of clinical interest since it is often encountered when assessing family history of RA specifically, but also informative on the genetic overlap between these diseases. Since anticitrullinated peptide antibodies/rheumatoid factor (RF)-positive and RF-negative RA have both specific and shared genetic factors, the familial co-aggregation was assessed separately for seropositive and seronegative disease. Nested case-control study in prospectively recorded Swedish total population data. The Multi-Generation Register identified first-degree relatives. RA and arthritis-related diseases were ascertained through the nationwide patient register. RA serology was based on International Classification of Diseases tenth revision coded diagnoses, mainly reflecting RF. Familial risks were calculated using conditional logistic regression. Results were replicated using the Swedish rheumatology register. Familial co-aggregation was found between RA and every studied arthritis-related disease, but the magnitude varied widely, from juvenile idiopathic arthritis (JIA) (seropositive RA OR=3.98 (3.01 to 5.26); seronegative RA OR=5.70 (3.47 to 9.36)) to osteoarthritis (seropositive RA OR=1.03 (1.00 to 1.06); seronegative RA OR=1.05 (1.00 to 1.09)). The familial co-aggregation pattern of non-RA arthritis-related diseases was overall similar for seropositive and seronegative RA. Among those with family history of RA, relatives' other arthritis-related diseases conferred little or no additional risk. Although family history of several arthritis-related diseases may be useful to predict RA (eg, lupus and JIA), others (eg, osteoarthritis and arthralgia) are less useful. Seropositive and seronegative RA had rather similar familial co-aggregation patterns with arthritis-related diseases, suggesting that the two RA

  14. Results of brachytherapy boost in high risk breast cancer patients

    International Nuclear Information System (INIS)

    Battermann, J.J.

    1996-01-01

    Introduction: in breast conserving therapy the role of brachytherapy as a boost after whole breast irradiation is not clear. The series from the Netherlands Cancer Institute show a very high local control rate, but the question could be raised whether all these patients need a brachy boost. Therefore, it was decided at our institute, to deliver a brachy boost only to high risk patients, viz. patients with incomplete resection margins and/or extensive in situ cancer (ECI). Materials and methods: in the period 1988 through 1993 a total of 148 patients with 151 breast tumours received a boost on the tumour bed using brachytherapy. Age varied from 25 till 74 years, with a mean age of 52.3 years. Incomplete resection margins were found in 60 patients, ECI in 31 and both in 49 patients. In the majority of patients, the ECI component was not completely removed. T-stage was unknown in 9 patients. T1 in 83, T2 in 49 and T3 in 10. Nodal status was N0 in 119 and N1 in 33 patients. Infiltrating duct carcinoma was the most common histology. No infiltrating growth was found in 6 patients, but one patient presented a positive node. The interval period between day of operation and day of brachytherapy implantation was between 3 and 4 months in 62%. The mean interval between completion of beam irradiation and day of implantation was 18 days, while 12 patients received their brachytherapy previous to the beam irradiation. External irradiation was with two tangential fields and a total dose of 50 Gy in 25 fractions over 6 weeks (9 fractions in two weeks). The number of needles in two planes. Most patients were implanted under local anaesthesia. Dose rate in 97 patients was 51 - 60 cGy/h. Results: follow-up for patients alive varied from 2 years till 7 years with a mean follow-up period of 4 years. One hundred and twenty five patients are alive, including 6 patients with manifest metastases. Local recurrence was encountered in 8 patients (interval 14 - 60 months, mean 30 months), with

  15. 2017 Taiwan lipid guidelines for high risk patients.

    Science.gov (United States)

    Li, Yi-Heng; Ueng, Kwo-Chang; Jeng, Jiann-Shing; Charng, Min-Ji; Lin, Tsung-Hsien; Chien, Kuo-Liong; Wang, Chih-Yuan; Chao, Ting-Hsing; Liu, Ping-Yen; Su, Cheng-Huang; Chien, Shih-Chieh; Liou, Chia-Wei; Tang, Sung-Chun; Lee, Chun-Chuan; Yu, Tse-Ya; Chen, Jaw-Wen; Wu, Chau-Chung; Yeh, Hung-I

    2017-04-01

    statin to consolidate the CV protection in CKD patients. Mutations in LDL receptor, apolipoprotein B and PCSK9 genes are the common causes of FH. Diagnosis of FH usually depends on family history, clinical history of premature CAD, physical findings of xanthoma or corneal arcus and high levels of LDL-C. In addition to conventional lipid lowering therapies, adjunctive treatment with mipomersen, lomitapide, or PCSK9 inhibitors become necessary to further reduce LDL-C in patients with FH. Overall, these recommendations are to help the health care professionals in Taiwan to treat hyperlipidemia with current scientific evidences. We hope the prescription rate of lipid lowering drugs and control rate of hyperlipidemia in high risk patients could be increased by implementation of the clinical guidelines. The major purpose is to improve clinical outcomes of these high risk patients through the control of hyperlipidemia. Copyright © 2016. Published by Elsevier B.V.

  16. HPV vaccine acceptability in high-risk Greek men.

    Science.gov (United States)

    Hoefer, Lea; Tsikis, Savas; Bethimoutis, George; Nicolaidou, Electra; Paparizos, Vassilios; Antoniou, Christina; Kanelleas, Antonios; Chardalias, Leonidas; Stavropoulos, Georgios-Emmanouil; Schneider, John; Charnot-Katsikas, Angella

    2018-01-02

    HPV is associated with malignancy in men, yet there is a lack of data on HPV knowledge, vaccine acceptability, and factors affecting vaccine acceptability in Greek men. This study aims to identify determinants of knowledge and willingness to vaccinate against HPV among high-risk Greek men. Men (n = 298) between the ages of 18 and 55 were enrolled from the STI and HIV clinics at "Andreas Syggros" Hospital in Athens, Greece from July-October 2015. Participants completed a survey on demographics, economic factors, sexual history, HPV knowledge, and vaccine acceptability. The majority of participants were younger than 40 (76.6%) and unmarried (84.6%). Our sample was 31.2% MSM (men who have sex with men), and 20.1% were HIV-positive. Most participants (>90%) were aware that HPV is highly prevalent in both men and women; however, fewer identified that HPV causes cancers in both sexes (68%) and that vaccination protects men and women (67%). Amongst participants, 76.7% were willing to vaccinate themselves against HPV, 71.4% an adolescent son, and 69.3% an adolescent daughter. HIV-positive men were more likely to be willing to vaccinate themselves (OR 2.83, p = .015), a son (OR 3.3, p = .015) or a daughter (3.01, p = .020). Higher income levels were associated with increased willingness to vaccinate oneself (OR 1.32, p = .027), a son (1.33, p = .032) or daughter (1.34, p = .027). Although there is a HPV knowledge gap, HPV vaccine acceptability is high despite lack of vaccine promotion to Greek men. Future studies should include lower-risk men to adequately inform public health efforts.

  17. High-Risk Sexual Behavior at Social Venues in Madagascar

    Science.gov (United States)

    KHAN, MARIA R.; RASOLOFOMANANA, JUSTIN R.; McCLAMROCH, KRISTI J.; RALISIMALALA, ANDRIAMAMPIANINA; ZAFIMANJAKA, MAURICE G.; BEHETS, FRIEDA; WEIR, SHARON S.

    2018-01-01

    Background Persistent high levels of sexually transmitted infection (STI) in Madagascar indicate current prevention strategies are inadequate. STI/HIV prevention based in social venues may play an important role in reaching individuals at risk of infection. We identified venues where people meet sexual partners and measured the need and potential for venue-based prevention. Methods Interviews were conducted in 7 Madagascar towns with 1) community informants to identify social venues, 2) individuals socializing at a sample of venues to assess sexual behavior among venue patrons, and 3) venue representatives to assess the potential for venue-based intervention. Results Community informants identified numerous venues (range: 67–211 venues, depending on the town); streets, bars, and hotels were most commonly reported. Among 2982 individuals socializing at venues, 78% of men and 74% of women reported new sexual partnership or sex trade for money, goods, or services in the past 4 weeks and 19% of men and 18% of women reported symptoms suggestive of STI in the past 4 weeks. STI symptom levels were disproportionately high among respondents reporting either sex trade or new sexual partnership in the past 4 weeks. Twenty-eight percent of men and 41% of women reported condom use during the last sex act with a new partner. Although 24% to 45% of venues had hosted STI/HIV interventions, interventions were deemed possible at 73% to 90% venues according to 644 interviews with venue representatives. Conclusions Venue-based intervention is possible and would reach a spectrum of populations vulnerable to STI/HIV including sex workers, their clients, and other high-risk populations. PMID:18496471

  18. A role for 5alpha-reductase activity in the development of male homosexuality?

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    Alias, A G

    2004-12-01

    Higher body hair with lower mesmorphism ratings were observed in Caucasian homosexual men compared with the general male population, reflecting elevated 5alpha-reductase (5alphaR) activity, and higher dihydrotestosterone-to-testosterone (DHT-to-T) ratio, in sharp contrast to 46,XY 5alphaR 2 deficiency subjects, who are often born with ambiguous, or female genitalia, but tend to grow up to be muscular, heterosexual men with very little body hair, or beard. One study also showed them scoring around dull normal IQs. A greater prevalence of liberal body hair growth in men with higher IQs and/or educational levels was also observed in several samples. The exceptions to this statistical trend are too unsettling, however. Nevertheless, the results of a number of published studies, including one showing higher DHT-to-T ratio in homosexual men, done with different objectives over a span of 80 years, together strongly support these findings. Furthermore, in an animal model, "cognitive-enhancing effects" of "5alpha-reduced androgen [metabolites]" were recently demonstrated.

  19. Homosexual Fellatio: Erect Penis Licking between Male Bonin Flying Foxes Pteropus pselaphon.

    Science.gov (United States)

    Sugita, Norimasa

    2016-01-01

    A recent focus of interest has been on the functional significance of genital licking (fellatio and cunnilingus) in relation to sexual selection in Pteropodid bats. In the present paper, a form of fellatio in wild Bonin flying foxes, Pteropus pselaphon, performed between adult males has been reported. During the mating season, adult flying foxes roost in same-sex groups, forming ball-shaped clusters which provide warmth. The female clusters may also contain a few males. Unassociated with allogrooming, same-sex genital licking occurred among males in the all male clusters. As such, male-male fellatio can be considered as homosexual behavior, two functional explanations could account for this behavior; the social bonding and the social tension regulation hypotheses suggested in a previous review. Given that neither the simpler alternative that in all male groups such fellatio may represent misdirected sexual behavior, nor the two previously proposed functional hypotheses were supported by the data, I propose another functional hypothesis. Homosexual fellatio in this species could help males solve inconsistent situations in the roost when there are conflicts between cooperative behavior for social thermoregulation and competition for mating.

  20. Homosexual Fellatio: Erect Penis Licking between Male Bonin Flying Foxes Pteropus pselaphon.

    Directory of Open Access Journals (Sweden)

    Norimasa Sugita

    Full Text Available A recent focus of interest has been on the functional significance of genital licking (fellatio and cunnilingus in relation to sexual selection in Pteropodid bats. In the present paper, a form of fellatio in wild Bonin flying foxes, Pteropus pselaphon, performed between adult males has been reported. During the mating season, adult flying foxes roost in same-sex groups, forming ball-shaped clusters which provide warmth. The female clusters may also contain a few males. Unassociated with allogrooming, same-sex genital licking occurred among males in the all male clusters. As such, male-male fellatio can be considered as homosexual behavior, two functional explanations could account for this behavior; the social bonding and the social tension regulation hypotheses suggested in a previous review. Given that neither the simpler alternative that in all male groups such fellatio may represent misdirected sexual behavior, nor the two previously proposed functional hypotheses were supported by the data, I propose another functional hypothesis. Homosexual fellatio in this species could help males solve inconsistent situations in the roost when there are conflicts between cooperative behavior for social thermoregulation and competition for mating.

  1. Quality of life of homosexual males with genital warts: a qualitative study

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    Larsen Helle K

    2010-11-01

    Full Text Available Abstract Background A recent qualitative study in Denmark showed that genital warts (GWs can considerably lower the quality of life of heterosexual patients. In this follow-up study, we interviewed men having sex with men (MSM suffering from GWs to obtain an in-depth understanding of their perception of GWs and determine the extent to which minority (homosexual cultural issues affect these patients' experiences. Qualitative interviews with six MSM were performed using a semi-structured interview guide. Questions were formulated on the basis of the earlier qualitative study in heterosexual patients with GWs along with a literature review. Data were analysed using a medical anthropological approach. Findings Many MSM worried about being stigmatised and excluded from the small homosexual 'scene', their key social group, thereby lowering their chances of finding sex and love. Most participants had suffered from GWs for several years which added to the negative psycho-sexual and social effects of the disease. Participants' fears of developing anal cancer were similar to those expressed about cervical cancer by females with GWs. Conclusions Ano-genital human papillomavirus (HPV infection is common and has a serious psychological and sexual impact among MSM. However, they do not benefit to the same extent as heterosexual men from the herd immunity effect of HPV vaccination of girls. The pathological profile and concerns specific to MSM should be addressed when communicating with these patients, and should be taken into account when considering HPV vaccination of boys.

  2. Homosexuals, dykes and queers: political positions in the lesbian and gay movement

    Directory of Open Access Journals (Sweden)

    Coll-Planas, Gerard

    2008-11-01

    Full Text Available (English In this article I aim to explore conflicts among the variety of political projects in the lesbian and gay movement.I base the article on Alberto Mira’s (2004 proposed models for the expression of homosexuality: decadentist, homophile and camp. I discuss the main theoretical and political debates that arise from these models. Firstly, I ask whether life on the margins of mainstream social rules allows gays and lesbians to live a freer existence or merely means internalised homophobia (using Jean Genet’s and Michel Foucault’s approaches as examples. Secondly, I question whether the demand for “normality” entails the creation of new exclusions (following Judith Butler’s approach to normality: Finally, I consider whether camp culture reproduces and/or subverts gender rules (introducing a discussion between Sheila Jeffreys and Judith Butler’s positions. On the basis of this exploration of Mira's three cultural models, I develop a typology of political positions ('normalization of homosexuality', 'transformation' and 'queer', which I apply to the case study of the Catalan lesbian and gay movement.

  3. Homosexuals, dykes and queers: political positions in the lesbian and gay movement

    Directory of Open Access Journals (Sweden)

    Gerard Coll-Planas

    2008-10-01

    Full Text Available In this article I aim to explore conflicts among the variety of political projects in the lesbian and gay movement.I base the article on Alberto Mira’s (2004 proposed models for the expression of homosexuality: decadentist, homophile and camp. I discuss the main theoretical and political debates that arise from these models. Firstly, I ask whether life on the margins of mainstream social rules allows gays and lesbians to live a freer existence or merely means internalised homophobia (using Jean Genet’s and Michel Foucault’s approaches as examples. Secondly, I question whether the demand for “normality” entails the creation of new exclusions (following Judith Butler’s approach to normality: Finally, I consider whether camp culture reproduces and/or subverts gender rules (introducing a discussion between Sheila Jeffreys and Judith Butler’s positions. On the basis of this exploration of Mira's three cultural models, I develop a typology of political positions ('normalization of homosexuality', 'transformation' and 'queer', which I apply to the case study of the Catalan lesbian and gay movement.

  4. Gender-related traits of heterosexual and homosexual men and women.

    Science.gov (United States)

    Lippa, Richard A

    2002-02-01

    Two studies investigated the relation between sexual orientation and gender-related traits. Analyzing data from an Internet survey, Study 1 found that gay men and lesbians differed from same-sex heterosexuals most strongly on gender diagnosticity (GD) measures, which assess male- versus female-typicality of occupational preferences (effect sizes were 1.14 for men and 0.53 for women) and least strongly on instrumentality (I) and expressiveness (E). Study 2 found that GD measures showed large differences between 289 gay and 200 heterosexual men (d = 0.95) and between 296 lesbian and 435 heterosexual women (d = 1.32), whereas I and E showed much smaller differences. In Study 2 homosexual-heterosexual diagnosticity measures, computed from men's and women's occupational preferences, correlated very strongly with GD measures (r = 0.88 for men and 0.89 for women), indicating that occupational preference items that distinguished men from women also tended to distinguish heterosexual from homosexual individuals. LISREL 8 analyses showed that self-ascribed masculinity-femininity did not mediate the strong relation between sexual orientation and GD for men or for women.

  5. Recreational Drug Use and Risk of Kaposi's Sarcoma in HIV- and HHV-8-Coinfected Homosexual Men

    Science.gov (United States)

    Chao, Chun; Jacobson, Lisa P.; Jenkins, Frank J.; Tashkin, Donald; Martínez-Maza, Otoniel; Roth, Michael D.; Ng, Leslie; Margolick, Joseph B.; Chmiel, Joan S.; Detels, Roger

    2009-01-01

    Abstract Experimental data suggested that exposure to recreational drugs might adversely affect antitumor immunity, which led us to examine the hypothesis that use of marijuana, cocaine, poppers, and amphetamines might increase the risk of Kaposi's Sarcoma (KS) in HIV- and HHV-8-coinfected homosexual men. We analyzed data prospectively collected from the Multicenter AIDS Cohort Study (MACS) between 1984 and 2002. Among the 1335 HIV- and HHV-8-coinfected white men, 401 KS cases were identified. Multivariable Cox regression models were used to estimate the effects of time-varying recreational drug use on KS risk adjusting for potential confounders. The effects of both recent use (6 months prior) of recreational drugs and lagged exposure (i.e., use from 3 and 5 years prior) were examined. We did not observe any clear association with KS for recent use of any of the four drugs. In the analyses using lagged exposures, KS risk was associated with use of poppers 3–5 years prior [hazard ratio (HR)3 years prior = 1.27, 95% CI (0.97–1.67), HR5 years prior = 1.46 (1.01–2.13)]. However, no clear dose-response relationship was observed. These findings do not support a biological association between use of these substances and KS development in HIV- and HHV-8-coinfected homosexual men. PMID:19108691

  6. Taking prisoners: Havelock Ellis, Sigmund Freud, and the construction of homosexuality, 1897-1951.

    Science.gov (United States)

    Crozier, I D

    2000-12-01

    This paper addresses the efforts of both Havelock Ellis and Sigmund Freud to posit a theory of homosexuality, and especially considers their efforts to (re-)negotiate each other's theories. Its central premise derives from the sociology of scientific knowledge: that it is not what is written, but the way that what is written is treated by ensuing experts, that makes knowledge. In the case study used in this paper, Ellis and Freud struggle to posit what they consider to be the proper model for understanding homosexual desire. They utilize aspects of each other's word, but are careful not to appear to be following each other too closely. Such a struggle to establish different schools of thought is exemplified by the informal negotiations engaged in when a student, Joseph Wortis, made contact with both Freud and Ellis. Again following sociology of scientific knowledge precepts, these informal negotiations (contained in published and archival letters) are used to show how knowledge claims are constructed, deconstructed any reconstructed by the actors who have stakes in the outcome of what is to be regarded as knowledge in the relevant communities.

  7. Preferred and Actual Relative Height among Homosexual Male Partners Vary with Preferred Dominance and Sex Role

    Science.gov (United States)

    Valentova, Jaroslava Varella; Stulp, Gert; Třebický, Vít; Havlíček, Jan

    2014-01-01

    Previous research has shown repeatedly that human stature influences mate preferences and mate choice in heterosexuals. In general, it has been shown that tall men and average height women are most preferred by the opposite sex, and that both sexes prefer to be in a relationship where the man is taller than the woman. However, little is known about such partner preferences in homosexual individuals. Based on an online survey of a large sample of non-heterosexual men (N = 541), we found that the majority of men prefer a partner slightly taller than themselves. However, these preferences were dependent on the participant’s own height, such that taller men preferred shorter partners, whereas shorter men preferred taller partners. We also examined whether height preferences predicted the preference for dominance and the adoption of particular sexual roles within a couple. Although a large proportion of men preferred to be in an egalitarian relationship with respect to preferred dominance (although not with respect to preferred sexual role), men that preferred a more dominant and more “active” sexual role preferred shorter partners, whereas those that preferred a more submissive and more “passive” sexual role preferred taller partners. Our results indicate that preferences for relative height in homosexual men are modulated by own height, preferred dominance and sex role, and do not simply resemble those of heterosexual women or men. PMID:24466136

  8. Prevalence of infection and genotypes of GBV-C/HGV among homosexual men.

    Science.gov (United States)

    Hattori, Junko; Ibe, Shiro; Nagai, Hiromi; Wada, Kaoru; Morishita, Takayuki; Sato, Katsuhiko; Utsumi, Makoto; Kaneda, Tsuguhiro

    2003-01-01

    Since the discovery of GB virus-C (GBV-C) and hepatitis G virus (HGV), many studies have been performed. These viruses are now known to be parenterally, as well as sexually transmitted. A phylogenetic analysis also revealed that GBV-C has five major genotypes: type 1 predominates in West Africa, type 2 in Europe and the United States, type 3 in parts of Asia, type 4 in Southeast Asia, and type 5 in South Africa. Despite the number of reports so far, there have been few large-scale surveys of homosexual men to determine the prevalence of the GBV-C/HGV infections. We examined the levels of GBV-C/HGV viremia in 297 homosexual men who attended the Nagoya Lesbian and Gay Revolution held in Nagoya, Japan. Reverse transcription-polymerase chain reaction (RT-PCR)/nested PCR of the GBV-C/HGV 5 ' -non-coding region (NCR), and base sequence analyses showed that the infection rate was 12.5%, and genotypes in this population were classified into type 2 (32%) and type 3 (68%). None were classified as types 1, 4, or 5 in this study. Our results indicate that the GBV-C/HGV type 2 seen mainly in Europe and the US is spreading widely in Japan, especially in the Nagoya district.

  9. Preferred and actual relative height among homosexual male partners vary with preferred dominance and sex role.

    Science.gov (United States)

    Valentova, Jaroslava Varella; Stulp, Gert; Třebický, Vít; Havlíček, Jan

    2014-01-01

    Previous research has shown repeatedly that human stature influences mate preferences and mate choice in heterosexuals. In general, it has been shown that tall men and average height women are most preferred by the opposite sex, and that both sexes prefer to be in a relationship where the man is taller than the woman. However, little is known about such partner preferences in homosexual individuals. Based on an online survey of a large sample of non-heterosexual men (N = 541), we found that the majority of men prefer a partner slightly taller than themselves. However, these preferences were dependent on the participant's own height, such that taller men preferred shorter partners, whereas shorter men preferred taller partners. We also examined whether height preferences predicted the preference for dominance and the adoption of particular sexual roles within a couple. Although a large proportion of men preferred to be in an egalitarian relationship with respect to preferred dominance (although not with respect to preferred sexual role), men that preferred a more dominant and more "active" sexual role preferred shorter partners, whereas those that preferred a more submissive and more "passive" sexual role preferred taller partners. Our results indicate that preferences for relative height in homosexual men are modulated by own height, preferred dominance and sex role, and do not simply resemble those of heterosexual women or men.

  10. Preferred and actual relative height among homosexual male partners vary with preferred dominance and sex role.

    Directory of Open Access Journals (Sweden)

    Jaroslava Varella Valentova

    Full Text Available Previous research has shown repeatedly that human stature influences mate preferences and mate choice in heterosexuals. In general, it has been shown that tall men and average height women are most preferred by the opposite sex, and that both sexes prefer to be in a relationship where the man is taller than the woman. However, little is known about such partner preferences in homosexual individuals. Based on an online survey of a large sample of non-heterosexual men (N = 541, we found that the majority of men prefer a partner slightly taller than themselves. However, these preferences were dependent on the participant's own height, such that taller men preferred shorter partners, whereas shorter men preferred taller partners. We also examined whether height preferences predicted the preference for dominance and the adoption of particular sexual roles within a couple. Although a large proportion of men preferred to be in an egalitarian relationship with respect to preferred dominance (although not with respect to preferred sexual role, men that preferred a more dominant and more "active" sexual role preferred shorter partners, whereas those that preferred a more submissive and more "passive" sexual role preferred taller partners. Our results indicate that preferences for relative height in homosexual men are modulated by own height, preferred dominance and sex role, and do not simply resemble those of heterosexual women or men.

  11. Sexual Excitability and Dysfunctional Coping Determine Cybersex Addiction in Homosexual Males.

    Science.gov (United States)

    Laier, Christian; Pekal, Jaro; Brand, Matthias

    2015-10-01

    Cybersex addiction (CA) has been mostly investigated in heterosexual males. Recent findings have demonstrated an association between CA severity and indicators of sexual excitability, and that coping by sexual behaviors mediated the relationship between sexual excitability and CA symptoms. The aim of this study was to test this mediation in a sample of homosexual males. Seventy-one homosexual males were surveyed online. Questionnaires assessed symptoms of CA, sensitivity to sexual excitation, pornography use motivation, problematic sexual behavior, psychological symptoms, and sexual behaviors in real life and online. Moreover, participants viewed pornographic videos and indicated their sexual arousal before and after the video presentation. Results showed strong correlations between CA symptoms and indicators of sexual arousal and sexual excitability, coping by sexual behaviors, and psychological symptoms. CA was not associated with offline sexual behaviors and weekly cybersex use time. Coping by sexual behaviors partially mediated the relationship between sexual excitability and CA. The results are comparable with those reported for heterosexual males and females in previous studies and are discussed against the background of theoretical assumptions of CA, which highlight the role of positive and negative reinforcement due to cybersex use.

  12. Remembering gay/lesbian media characters: can Ellen and Will improve attitudes toward homosexuals?.

    Science.gov (United States)

    Bonds-Raacke, Jennifer M; Cady, Elizabeth T; Schlegel, Rebecca; Harris, Richard J; Firebaugh, Lindsey

    2007-01-01

    The purpose of the current research was twofold. First, a pilot study was conducted in which participants were asked to recall any memorable gay or lesbian television or film character and complete a survey about their perceptions of the character. Results indicated that over two-thirds of heterosexual participants recalled either Ellen or Will, and evaluative ratings for these characters were generally positive. The second purpose of this research was to examine the priming effects of remembering portrayals of homosexual characters in the media. Therefore, an experiment was conducted to directly assess the effects of thinking about either a positive or negative homosexual character on general heterosexuals' attitudes toward gay men and lesbians. Results indicated that those recalling a positive portrayal later showed a more positive attitude toward gay men than those recalling a negative portrayal, and women had a more positive attitude overall than men toward gay men and lesbians. Such findings illustrate the importance of positive role models in entertainment media as potential primes of social attitudes.

  13. Homosexuality via canalized sexual development: a testing protocol for a new epigenetic model.

    Science.gov (United States)

    Rice, William R; Friberg, Urban; Gavrilets, Sergey

    2013-09-01

    We recently synthesized and reinterpreted published studies to advance an epigenetic model for the development of homosexuality (HS). The model is based on epigenetic marks laid down in response to the XX vs. XY karyotype in embryonic stem cells. These marks boost sensitivity to testosterone in XY fetuses and lower it in XX fetuses, thereby canalizing sexual development. Our model predicts that a subset of these canalizing epigenetic marks stochastically carry over across generations and lead to mosaicism for sexual development in opposite-sex offspring--the homosexual phenotype being one such outcome. Here, we begin by outlining why HS has been under-appreciated as a commonplace phenomenon in nature, and how this trend is currently being reversed in the field of neurobiology. We next briefly describe our epigenetic model of HS, develop a set of predictions, and describe how epigenetic profiles of human stem cells can provide for a strong test of the model. © 2013 The Authors. Bioessays published by WILEY Periodicals, Inc.

  14. Between memory and silence, the late testimony of a deported homosexual

    Directory of Open Access Journals (Sweden)

    Marcelo Spitzner

    2014-10-01

    Full Text Available http://dx.doi.org/10.5007/2175-7917.2014v19n2p61 This article focuses on the biography of Rudolf Brazda, written by Jean-Luc Schwab. This biography narrates the life and, especially, the deportation of Rudolf Bradzda to the concentration camp of Buchenwald, due to his homosexuality. Brazda was the last pink triangle, title given to homosexuals who were deported to Nazi concentration camps, and one of the few who managed to leave his testimony recorded, even though the writing of another. Thus, I seek in theoretical reflections on history, memory and modernity, a way to point out that narratives such as Brazda’s are delayed or difficult to enter in the collective memory and, therefore, narrate them is configured as struggles against oblivion, silencing and it is a reconstitution of the limits of the historical narrative. Through this text, I propose that history is not made of lines but of wrinkles, the temporality must constantly be revised and that the objective image of collective experience that sustained modernity must be shaken and other genealogies of human experience must be build.

  15. Herpes simplex virus proctitis in homosexual men. Clinical, sigmoidoscopic, and histopathological features.

    Science.gov (United States)

    Goodell, S E; Quinn, T C; Mkrtichian, E; Schuffler, M D; Holmes, K K; Corey, L

    1983-04-14

    Acute herpes simplex virus (HSV) infection was detected in 23 of 102 consecutively examined, sexually active male homosexuals who presented with anorectal pain, discharge, tenesmus, or hematochezia, as compared with 3 of 75 homosexual men without gastrointestinal symptoms (P less than 0.01). Findings that were significantly more frequent in men with HSV proctitis than in men with proctitis due to other infectious causes included fever (48 per cent), difficulty in urinating (48 per cent), sacral paresthesias (26 per cent), inguinal lymphadenopathy (57 per cent), severe anorectal pain (100 per cent), tenesmus (100 per cent), constipation (78 per cent), perianal ulcerations (70 per cent), and the presence of diffuse ulcerative or discrete vesicular or pustular lesions in the distal 5 cm of the rectum (50 per cent). Serologic evidence indicated that 85 per cent of the men with symptomatic HSV proctitis were having their first episode of HSV-2 infection. The diagnosis of HSV proctitis is suggested by the presence of severe anorectal pain, difficulty in urinating, sacral paresthesias or pain, and diffuse ulceration of the distal rectal mucosa.

  16. Changes in Vaginal Microbiota and Immune Mediators in HIV-1-Seronegative Kenyan Women Initiating Depot Medroxyprogesterone Acetate.

    Science.gov (United States)

    Roxby, Alison C; Fredricks, David N; Odem-Davis, Katherine; Ásbjörnsdóttir, Kristjana; Masese, Linnet; Fiedler, Tina L; De Rosa, Stephen; Jaoko, Walter; Kiarie, James N; Overbaugh, Julie; McClelland, R Scott

    2016-04-01

    Depot medroxyprogesterone acetate (DMPA) is associated with HIV acquisition. We studied changes in vaginal microbiota and inflammatory milieu after DMPA initiation. In a cohort of HIV-negative Kenyan women, we collected monthly vaginal swabs over 1 year before and after DMPA. Using quantitative polymerase chain reaction, we compared quantities of Lactobacillus crispatus, Lactobacillus jensenii, Lactobacillus iners, Gardnerella vaginalis, and total bacterial load (16S ribosomal RNA gene levels). Six vaginal immune mediators were measured with enzyme-linked immunosorbent assay. Trends in the detection and quantity of bacteria were estimated by logistic and linear mixed-effects regression. From 2010 to 2012, 15 HIV-seronegative women initiated DMPA, contributing 85 visits (median, 6 visits/woman; range, 3-8 visits/woman). The median time of DMPA-exposed follow-up was 8.4 months (range, 1.5-11.6 months). Seven women (46%) had bacterial vaginosis within 70 days before DMPA start. L. iners was detected in 13 women (87%) before DMPA start, but other lactobacilli were rarely detected. Gardnerella vaginalis decreased by 0.21 log10 copies per swab per month after DMPA exposure (P = 0.01). Total bacterial load decreased by 0.08 log10 copies per swab per month of DMPA (P = 0.02). Sustained decreases in interleukin (IL)-6 (P = 0.03), IL-8 (P = 0.04), and IL-1 receptor antagonist (P vaginal bacterial concentrations and levels of inflammatory mediators. Further studies are warranted to outline components of the vaginal microbiota influenced by DMPA use and impact on HIV susceptibility.

  17. A Phase 1 Study of 4 Live, Recombinant Human Cytomegalovirus Towne/Toledo Chimera Vaccines in Cytomegalovirus-Seronegative Men.

    Science.gov (United States)

    Adler, Stuart P; Manganello, Anne-Marie; Lee, Ronzo; McVoy, Michael A; Nixon, Daniel E; Plotkin, Stanley; Mocarski, Edward; Cox, Josephine H; Fast, Patricia E; Nesterenko, Pavlo A; Murray, Susan E; Hill, Ann B; Kemble, George

    2016-11-01

     Human cytomegalovirus (HCMV) infection causes disease in newborns and transplant recipients. A HCMV vaccine (Towne) protects transplant recipients.  The genomes of Towne and the nonattenuated Toledo strain were recombined, yielding 4 Towne/Toledo chimera vaccines. Each of 36 HCMV-seronegative men received 1 subcutaneous dose of 10, 100, or 1000 plaque-forming units (PFU) in cohorts of 3. Safety and immunogenicity were evaluated over 12 weeks after immunization and for 52 weeks for those who seroconverted.  There were no serious local or systemic reactions. No subject had HCMV in urine or saliva. For chimera 3, none of 9 subjects seroconverted. For chimera 1, 1 of 9 seroconverted (the seroconverter received 100 PFU). For chimera 2, 3 subjects seroconverted (1 received 100 PFU, and 2 received 1000 PFU). For chimera 4, 7 subjects seroconverted (1 received 10 PFU, 3 received 100 PFU, and 3 received 1000 PFU). All 11 seroconverters developed low but detectable levels of neutralizing activity. CD4 + T-cell responses were detectable in 1 subject (who received 100 PFU of chimera 4). Seven subjects receiving chimera 2 or 4 had detectable CD8 + T-cell responses to IE1; 3 responded to 1-2 additional antigens.  The Towne/Toledo chimera vaccine candidates were well tolerated and were not excreted. Additional human trials of chimeras 2 and 4 are appropriate.  NCT01195571. © The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail journals.permissions@oup.com.

  18. Risk of suicide in high risk pregnancy: an exploratory study.

    Science.gov (United States)

    Benute, Gláucia Rosana Guerra; Nomura, Roseli Mieko Yamamoto; Jorge, Vanessa Marques Ferreira; Nonnenmacher, Daniele; Fráguas Junior, Renério; Lucia, Mara Cristina Souza de; Zugaib, Marcelo

    2011-01-01

    To identify the risk of suicidal behavior in high-risk pregnant women at a public hospital in São Paulo. We conducted a semi-structured interview with each of the participants (n = 268) through a previously prepared questionnaire. Risk of suicidal behavior was assessed by the Portuguese version of PRIME-MD. The mean age of patients was 29 years (SD = 0.507) and gestation period was 30 weeks (SD = 0.556). Of the total sample, specific risk of suicide was found in 5% (n = 14). Of these, 85% have a stable relationship (married or cohabitating), the pregnancy was planned in 50% of cases, and 71% have no religion or professional activities. The correlation of risk of suicide with data from marital status, planned birth, age, education, professional practice, risk of prematurity, and religion showed that having a religion is statistically significant (p = 0.012). There were no positive associations for any of the other selected variables when compared with the risk of suicide. By correlating the risk of suicide with other characteristic symptoms of major depression, there was statistical significance in the sample with regard to insomnia or hypersomnia (p = 0.003), fatigue or loss of energy (p = 0.001), decreased or increased appetite (p = 0.005), less interest in daily activities (p = 0.000), depressed mood (p = 0.000), feelings of worthlessness or guilt (p = 0.000), decreased concentration (p = 0.002), and agitation or psychomotor retardation (p = 0.002). We found that religion can be a protective factor against suicidal behavior. Besides providing a social support network needed by women during pregnancy, religion supports belief in life after death and in a loving God, giving purpose to life and self esteem and providing models for coping with crises. The results show the importance of prevention and early diagnosis of suicidal behavior, since suicide is an attempt to move from one sphere to another by force, seeking to solve what seems impossible.

  19. Family studies to find rare high risk variants in migraine.

    Science.gov (United States)

    Hansen, Rikke Dyhr; Christensen, Anne Francke; Olesen, Jes

    2017-12-01

    variants (less than five), while other studies found several possible variants. Not all of them were genome wide significant. Four studies performed follow-up analyses in unrelated cases and controls and calculated odds ratios that supported an association between detected variants and risk of disease. Studies of 11 diseases identified rare variants that segregated fully or to a large degree with the disease in the pedigrees. It is possible to find rare high risk variants for common complex diseases through a family-based approach. One study using a family approach and NGS to find rare variants in migraine has already been published but with strong limitations. More studies are under way.

  20. Strong decline in herpes simplex virus antibodies over time among young homosexual men is associated with changing sexual behavior

    NARCIS (Netherlands)

    Dukers, N. H.; Bruisten, S. M.; van den Hoek, J. A.; de Wit, J. B.; van Doornum, G. J.; Coutinho, R. A.

    2000-01-01

    The objective of this study was to evaluate whether the change in sexual behavior among homosexual men observed after the start of the acquired immunodeficiency syndrome epidemic resulted in a change in herpes simplex virus (HSV) seroprevalence in this group over time. In a cross-sectional study,

  1. "Proper Masculinities" and the Fear of Feminisation in Modern Cyprus: University Students Talk about Homosexuality and Gendered Subjectivities

    Science.gov (United States)

    Onoufriou, Andreas

    2010-01-01

    The present article attempts to pay attention to the ways in which a group of young Cypriot students engage in the construction of conventional notions of masculinities through the negation and the fear of homosexual desire. Drawing on interviews with 12 male and female university students, I argue that many young men go through complicated…

  2. Low AIDS attack rate among Dutch haemophiliacs compared to homosexual men: a correlate of HIV antigenaemia frequencies

    NARCIS (Netherlands)

    Wolfs, T. F.; de Wolf, F.; Breederveld, C.; Sjamsjoedin-Visser, L. J.; Roos, M.; Bakker, M.; Goudsmit, J.

    1989-01-01

    A cohort of 180 haemophiliacs followed between 1983 and 1986 and a cohort of 961 homosexual men followed between 1984 and 1986 were compared for the prevalence and incidence of HIV-1 antibody (HIV-1-Ab) seropositivity, the incidence of AIDS-related complex (ARC) and AIDS and the prevalence and

  3. Religion and the rainbow struggle: does religion factor into attitudes toward homosexuality and same-sex civil unions in Brazil?

    Science.gov (United States)

    Ogland, Curtis P; Verona, Ana Paula

    2014-01-01

    The provision of civil liberties to LGBT persons has become part of a global movement in societies across the world. In Brazil, a recent judicial ruling for the first time established the right for homosexual couples to enter into civil unions, despite the presence of widespread disapproval of homosexuality among the population and opposition from prominent religious groups. Picking up on this issue, the following study examines whether religion may factor into the attitudes Brazilians hold toward homosexuality and same-sex civil unions. Using data from the Brazilian Social Research Survey, we find that the most restrictive views toward homosexuality and the strongest opposition to same-sex civil unions are most prevalent among devoted followers of historical Protestant, Pentecostal, and Catholic faith traditions, whereas adherents of Afro-Brazilian and spiritist religions, as well as those with no religious commitment, are inclined to assume a more tolerant moral posture toward such issues. The findings point to religion as a potential influence in future public policy initiatives and social movements involving LGBT issues in Brazil.

  4. The Dark Triad and three types of jealousy : Its’ relations among heterosexuals and homosexuals involved in a romantic relationship

    NARCIS (Netherlands)

    Barelds, Dick P.H.; Dijkstra, Pieternel; Groothof, Hinke A.K.; Pastoor, Charlotte D.

    2017-01-01

    The current study examined the relations between the three Dark Triad (DT) traits and three types of jealousy, among both heterosexual and homosexual men and women involved in a romantic relationship (n = 439). It was hypothesized that the three DT traits would be related positively to those types

  5. Secularization and changing moral views : European trends in church attendance and views on homosexuality, divorce, abortion, and euthanasia

    NARCIS (Netherlands)

    Halman, Loek; van Ingen, Erik

    2015-01-01

    Analysing survey data from the European Values Study, we investigate whether and how changes in church attendance bring about changes in people’s acceptance of abortion, homosexuality, divorce, and euthanasia. We argue that decreasing church attendance not only should enhance overall acceptance of

  6. After migration: Acculturation of attitudes towards homosexuality among Polish immigrants in Germany, Ireland, the Netherlands and the UK

    NARCIS (Netherlands)

    Röder, A.; Lubbers, M.

    2016-01-01

    Public opinion on homosexuality remains unfavourable in Poland, one of the main sending countries of migrants to Western Europe. This contrasts sharply with public opinion in many of the Western European receiving countries. Using data collected shortly after migration and in a second wave one and a

  7. Secularization and Changing Moral Views : European Trends in Church Attendance and Views on Homosexuality, Divorce, Abortion, and Euthanasia

    NARCIS (Netherlands)

    Halman, Loek; Van Ingen, Erik

    2014-01-01

    Analysing survey data from the European Values Study, we investigate whether and how changes in church attendance bring about changes in people's acceptance of abortion, homosexuality, divorce, and euthanasia. We argue that decreasing church attendance not only should enhance overall acceptance of

  8. Assessing the effects of anti-homosexuality legislation in Uganda on HIV prevention, treatment, and care services.

    Science.gov (United States)

    Semugoma, Paul; Beyrer, Chris; Baral, Stefan

    2012-01-01

    Uganda's response to the HIV epidemic has been lauded for its robustness and achievements. However, a key component of HIV prevention programming has been missing, for men who have sex with men (MSM). The main reason cited has been criminalization of male homosexual behavior. In 2009, the Anti-Homosexuality Bill (AHB) was introduced in the parliament to enhance existing anti-homosexuality law. A multi-disciplinary team made a Health Impact Assessment of the proposed AHB. The bill as tabled would severely increase punishments, increased closeting. Social capital of MSM would be eroded by clauses mandating reporting by friends, relatives, and acquaintances. Health-care professionals would have to inform on homosexuals. Mandatory HIV testing would be a blow to programming. Probable disclosure of HIV status in a public space (court) would also be a deterrent. Heftier punishments for those testing positive increases stigma and hobbles subsequent care. The AHB argues for exclusion, and more discrimination targeting persons living with HIV and sexual minorities. It will exacerbate the negative public health consequences of the existing legislation. The government of Uganda should review guidance documents published by authoritative bodies including the World Bank, World Health Organization to develop and bring to scale Human rights-affirming HIV prevention, treatment, and care responses.

  9. Homosexuální rodičovství jako prostor pro změnu

    Czech Academy of Sciences Publication Activity Database

    Sloboda, Zdeněk

    2008-01-01

    Roč. 6, č. 11 (2008), s. 14-15 ISSN 1214-1720 R&D Projects: GA AV ČR 1QS700280503 Institutional research plan: CEZ:AV0Z70280505 Keywords : homosexuality * parenting * family Subject RIV: AO - Sociology, Demography http://www.socioweb.cz/upl/editorial/download/152_socioweb_11_08.pdf

  10. "Homosexuality/Homophobia Is Un-African"?: Un-Mapping Transnational Discourses in the Context of Uganda's Anti-Homosexuality Bill/Act.

    Science.gov (United States)

    Wahab, Amar

    2016-01-01

    This article un-maps the recent impasse between pro- and antigay mobilization around Uganda's Anti-Homosexuality Act (AHA, 2009-2014). Drawing on scholarly and social media sources, it summarizes the increasing influence of (U.S.) transnational evangelism that has precipitated a state-religious complex of "anticipatory political homophobia" in Uganda. If transnational evangelism against same-sex sexuality in Uganda has generated a strong reaction from global LGBT human-rights advocates, this article critiques this Western homotransnationalist response by analyzing its limited terms of operation, focusing on the ways in which Uganda is hailed into the biopolitical project of a Western queer modernity. The author focuses on the copresence between homotransnationalist mobilization and "homophobic anticipatory countermobilization" as (re)organizing/suturing a global ordering project that is deeply invested in biopolitics and necropolitics. This suggests that the global flashpointing of Uganda in the context of the AHA incites further questions concerning the transnationality of "gay human rights" discourse under neoliberalism.

  11. A prospective cohort study comparing the effect of single-dose 2 g metronidazole on Trichomonas vaginalis infection in HIV-seropositive versus HIV-seronegative women.

    Science.gov (United States)

    Balkus, Jennifer E; Richardson, Barbra A; Mochache, Vernon; Chohan, Vrasha; Chan, Jeannie D; Masese, Linnet; Shafi, Juma; Marrazzo, Jeanne; Farquhar, Carey; McClelland, R Scott

    2013-06-01

    This analysis compared the frequency of persistent Trichomonas vaginalis (TV) among HIV-seropositive and HIV-seronegative women. Data were obtained from women enrolled in an open cohort study of sex workers in Kenya. Participants were examined monthly, and those diagnosed as having TV by saline microscopy were treated with single-dose 2 g oral metronidazole. All women on antiretroviral therapy (ART) used nevirapine-based regimens. Generalized estimating equations with a logit link were used to compare the frequency of persistent TV (defined as the presence of motile trichomonads by saline microscopy at the next examination visit within 60 days) by HIV status. Three-hundred sixty participants contributed 570 infections to the analysis (282 HIV-seropositive and 288 HIV-seronegative). There were 42 (15%) persistent infections among HIV-seropositive participants versus 35 (12%) among HIV-seronegative participants (adjusted odds ratio, 1.14; 95% confidence interval [CI], 0.70-1.87). Persistent TV was highest among HIV-seropositive women using ART (21/64 [33%]) compared with HIV-seropositive women not using ART (21/217 [10%]). Concurrent bacterial vaginosis (BV) at TV diagnosis was associated with an increased likelihood of persistent TV (adjusted odds ratio, 1.90; 95% confidence interval, 1.16-3.09). The frequency of persistent TV infection after treatment with single-dose 2 g oral metronidazole was similar by HIV status. Alternative regimens including multiday antibiotic treatment may be necessary to improve cure rates for women using nevirapine-based ART and women with TV and concurrent BV.

  12. Mycobacterium avium and purified protein derivative-specific cytotoxicity mediated by CD4+ lymphocytes from healthy HIV-seropositive and-seronegative individuals

    DEFF Research Database (Denmark)

    Ravn, P; Pedersen, B K

    1996-01-01

    mycobacteria. Our objective was to investigate the M.tuberculosis-and M. avium-specific cytotoxic capacity of T cells from healthy, bacille Calmette-Guérin-vaccinated, HIV-seropositive individuals. Blood mononuclear cells were obtained from 10 healthy HIV-seropositive and 10 healthy seronegative persons...... with no history of previous or active mycobacterial infection. Antigen-specific killing of macrophages presenting mycobacterial antigens (purified protein derivative or M. avium culture filtrate) was conducted. The phenotype of the killer cells was determined by a fluorescence-activated cell sorter after antigen...

  13. Compra impulsiva en el homosexual masculino en Barranquilla (Colombia: un estudio descriptivo

    Directory of Open Access Journals (Sweden)

    Vanya Guadalupe Alvarado López

    2005-01-01

    Full Text Available Esta investigación se basa en estudios realizados por Luna-Aroca en España y Denegri en Chile, mediante la aplicación de la escala de consumo de Luna-Aroca (2000, para describir las características de compra impulsiva del homosexual masculino en Barranquilla, Colombia. Los resultados indican que la compra impulsiva en los homosexuales masculinos en Barranquilla (Colombia se centra en la búsqueda de novedad, exclusividad y la relación hedónica entre el producto y la compra. Las áreas del self que más se relacionan con la compra impulsiva son la económica, la física (peso y la belleza.

  14. Restauration and revolution. Essay on the dialectics of the struggle for homosexual rights

    Directory of Open Access Journals (Sweden)

    Ivan Vuković

    2016-03-01

    Full Text Available The author analyses opinions expressed by the French philosopher Alain Badieu concerning the course and the outcome of ideological struggles led in the 20th century. Unlike Badieu who claims that the century ended with complete defeat of communist ideas, the author claims that the left had some success in the field of culture, in spite of all the loses in economy and politics. This thesis is illustrated by the example of the movement for homosexual rights. According to Badieu, this movement entered history with a revolutionary claim for a general liberation of human sexuality, and ended with the egoistic, petit-bourgeois request for the right to marriage. The author, on the other hand, thinks that the recognition of this second request augments sexual liberties and dynamics in the entire society, which means that the movement has fulfilled its general revolutionary function according Badieu’s own criteria.

  15. Gender-atypical personality or sexual behavior: What is disgusting about male homosexuality?

    Science.gov (United States)

    Caswell, T Andrew; Sackett-Fox, Kyrsten

    2018-01-15

    Research consistently finds that homosexuality elicits strong feelings of disgust, but the reasons remain unclear. In the current research, we investigate responses to gay men who violate social norms governing the expression of gender and sexuality. Two hundred forty-three college undergraduates read a vignette about a gay male college student whose personality traits (masculine, feminine, or neutral) and sexual behavior (active vs. passive) varied and reported their affective responses to and cognitive appraisals of the target. The gay target who displayed a feminine personality elicited more disgust and was perceived as lower in gender role conformity than a gay man who displayed a masculine personality. Similarly, the gay target who assumed a passive sex role elicited more disgust and was perceived as lower in gender role conformity than a gay man who assumed an active sex role. The sexual behavior/disgust relationship was mediated by perceived gender role conformity.

  16. Does Closeness to Someone Who Is Gay, Lesbian, or Bisexual Influence Etiology Beliefs About Homosexuality?

    Science.gov (United States)

    Chonody, Jill M; Kavanagh, Phillip S; Woodford, Michael R

    2016-12-01

    Research suggests that contact with sexual minorities and etiology beliefs regarding the origins of homosexuality are associated with antigay bias; however, factors related to etiology beliefs have received little empirical attention. Our primary research question is: Does closeness to someone who is gay, lesbian, or bisexual influence etiology beliefs? Students (n = 851) from four U.S. universities completed an anonymous survey, and regression results indicated that contact and closeness were not significantly associated with etiology beliefs. Because both contact and relationship closeness were associated with antigay attitudes, and closeness demonstrated the largest effect, we tested three alternative structural equation models to determine if contact and closeness mediated etiology beliefs. Results suggested that contact and the degree of closeness are indirectly associated with students' etiology beliefs through antigay bias.

  17. The rise of homosexuality and the dawn of communism in Hong Kong film: 1993-1998.

    Science.gov (United States)

    Grossman, A

    2000-01-01

    I have designed this essay as a general overview of the self-evident trend towards queer subject matter in the past decade in Hong Kong film, a trend that not only coincides historically with the 1997 handover to the Mainland but also frequently comes equipped with parent-child relationships that can be read as allegories for the colony's future as the "child" to its mother country. Queerness in HK films has both alternated between and combined indigenous forms of queerness and the imported Western variety; by charting courses through internationalized concepts of homosexuality, HK films have posited their queerness not only as an existential allegory of (post)colonialism but also as a claim (or hope) for a utopian sexuality cum utopian international politics.

  18. Enhancing masculinity by slandering homosexuals: the role of homophobic epithets in heterosexual gender identity.

    Science.gov (United States)

    Carnaghi, Andrea; Maass, Anne; Fasoli, Fabio

    2011-12-01

    The current studies investigate the effects of homophobic labels on the self-perception of heterosexual males, hypothesizing that when exposed to homophobic epithets, they are motivated to underline their masculinity and claim a distinctly heterosexual identity by taking distance from homosexuals and, to a lesser degree, from women. Heterosexual male participants were subliminally (Study 1) and supraliminally (Study 2) primed either by a homophobic epithet or by a category label, and completed the Traditional Beliefs About Gender and Gender Identity scale. Participants stressed their heterosexual identity, but not their gender distinctiveness, when exposed to homophobic epithets, compared to category labels. Study 2 demonstrated that the relation between the homophobic label and the participants' heterosexual identity was mediated by how negatively they reacted to the antigay label. Heterosexual identity was enhanced in reaction to homophobic labels but not to an equally derogatory label referring to regional identity. Results are discussed within an intergroup framework.

  19. The Homosexual Parenthood: An Exposition of the Psychoanalytical Debate in the Contemporary French Scenario

    Directory of Open Access Journals (Sweden)

    Simone Perelson

    2006-09-01

    Full Text Available After situating homoparenthood within the context of the new social and medical practices concerning parenthood and reproduction, the article presents a scenario of the contemporary French debate on this issue. The thinking of five psychoanalysts on this matter will be broached : Joël Dor and his theory about the role of the function of the father and about the anatomic difference between sexes in the structure process of the subject; Pierre Legendre and his articulation between the fields of law and the psych in the involvement of the human being in the order of parenthood; Michel Tort and his criticism of the theories of that author; and Genevieve Delaisi de Parseval and her proposal of a broader definition of the family. And, finally, Sabine Prokhoris, and her distinction between “sexuation” and “difference of the sexes”. This presentation intends to dismantle the opposite arguments and demonstrates the legitimacy of the reasoning favorable to homosexual parenthood.

  20. Security engineering: Phisical security measures for high-risk personnel

    Directory of Open Access Journals (Sweden)

    Jelena S. Cice

    2013-06-01

    Full Text Available The design of physical security measures is a specialized technical area that does not fall in the normal skill record and resume of commanders, architects, engineers, and project managers. This document provides guidance to those parties tasked with implementing existing and emerging physical protection system requirements: -    Creation of a single-source reference for the design and construction of physical security measures for high-risk personnel (HRP. -    Promulgation of multi-service standard recommendations and considerations. -    Potential increase of productivity of HRP and reduced temporary housing costs through clarification of considerations, guidance on planning, and provision of design solutions. -    Reduction of facility project costs. -    Better performance of modernized facilities, in terms of force protection, than original facilities. Throughout this process you must ensure: confidentiality, appropriate Public Relations, sustainability, compliance with all industrial guidelines and legal and regulatory requirement, constant review and revision to accommodate new circumstances or threats. Introduction Physical security is an extremely broad topic. It encompasses access control devices such as smart cards, air filtration and fireproofing. It is also heavily reliant on infrastructure. This means that many of the ideal physical security measures may not be economically or physically feasible for existing sites. Many businesses do not have the option of building their own facility from the ground up; thus physical security often must be integrated into an existing structure. This limits the overall set of security measures that can be installed. There is an aspect of physical security that is often overlooked; the humans that interact with it. Humans commit crime for a number of reasons. The document focuses on two building types: the HRP office and the HRP residence. HRP are personnel who are likely to be