WorldWideScience

Sample records for high-resolution converters ads1211

  1. Total Ionizing Dose Effects on High Resolution (12-/14-bit) Analog-to-Digital Converters

    Science.gov (United States)

    Lee, C. I.; Rax, B. G.; Johnson, A. H.

    1994-01-01

    This paper reports total dose radiation test results for high resolution 12-/14-bit A/D converters. Small changes in internal components can cause these devices to fail their specifications at relatively low total dose levels. Degradation of signal-to-noise ratio becomes increasingly importamt for high accuracy converters. Rebound effects in the thick-oxide MOS devices causes these responses to be different at low and high dose rates, which is a major concern for space applications.

  2. High Speed High Resolution Current Comparator and its Application to Analog to Digital Converter

    Science.gov (United States)

    Sridhar, Ranjana; Pandey, Neeta; Bhattacharyya, Asok; Bhatia, Veepsa

    2016-06-01

    This paper introduces a high speed high resolution current comparator which includes the current differencing stage and employs non linear feedback in the gain stage. The usefulness of the proposed comparator is demonstrated by implementing a 3-bit current mode flash analog-to-digital converter (ADC). Simulation program with integrated circuit emphasis (SPICE) simulations have been carried out to verify theoretical proposition and performance parameters of both comparator and ADC are obtained using TSMC 0.18 µm CMOS technology parameters. The current comparator shows a resolution of ±5 nA and a delay of 0.86 ns for current difference of ±1 µA. The impact of process variation on proposed comparator propagation delay has been studied through Monte Carlo simulation and it is found that percentage change in propagation delay in best case is 1.3 % only and in worst case is 9 % only. The ADC exhibits an offset, gain error, differential nonlinearity (DNL) and integral nonlinearity (INL) of 0.102 µA, 0.99, -0.34 LSB and 0.0267 LSB, respectively. The impact of process variation on ADC has also been studied at different process corners.

  3. Development of a High-performance Optical System and Fluorescent Converters for High-resolution Neutron Imaging

    Science.gov (United States)

    Sakai, T.; Yasuda, R.; Iikura, H.; Nojima, T.; Matsubayashi, M.

    Two novel devices for use in neutron imaging technique are introduced. The first one is a high-performance optical lens for video camera systems. The lens system has a magnification of 1:1 and an F value of 3. The optical resolution is less than 5 μm. The second device is a high-resolution fluorescent plate that converts neutrons into visible light. The fluorescent converter material consists of a mixture of 6LiF and ZnS(Ag) fine powder, and the thickness of the converter is material is as little as 15 μm. The surface of the plate is coated with a 1 μm-thick gadolinium oxide layer. This layer is optically transparent and acts as an electron emitter for neutron detection. Our preliminary results show that the developed optical lens and fluorescent converter plates are very promising for high-resolution neutron imaging.

  4. High Resolution Switching Mode Inductance-to-Frequency Converter with Temperature Compensationti

    Science.gov (United States)

    Matko, Vojko; Milanović, Miro

    2014-01-01

    This article proposes a novel method for the temperature-compensated inductance-to-frequency converter with a single quartz crystal oscillating in the switching oscillating circuit to achieve better temperature stability of the converter. The novelty of this method lies in the switching-mode converter, the use of additionally connected impedances in parallel to the shunt capacitances of the quartz crystal, and two inductances in series to the quartz crystal. This brings a considerable reduction of the temperature influence of AT-cut crystal frequency change in the temperature range between 10 and 40 °C. The oscillator switching method and the switching impedances connected to the quartz crystal do not only compensate for the crystal's natural temperature characteristics but also any other influences on the crystal such as ageing as well as from other oscillating circuit elements. In addition, the method also improves frequency sensitivity in inductance measurements. The experimental results show that through high temperature compensation improvement of the quartz crystal characteristics, this switching method theoretically enables a 2 pH resolution. It converts inductance to frequency in the range of 85–100 μH to 2–560 kHz. PMID:25325334

  5. High resolution switching mode inductance-to-frequency converter with temperature compensation.

    Science.gov (United States)

    Matko, Vojko; Milanović, Miro

    2014-10-16

    This article proposes a novel method for the temperature-compensated inductance-to-frequency converter with a single quartz crystal oscillating in the switching oscillating circuit to achieve better temperature stability of the converter. The novelty of this method lies in the switching-mode converter, the use of additionally connected impedances in parallel to the shunt capacitances of the quartz crystal, and two inductances in series to the quartz crystal. This brings a considerable reduction of the temperature influence of AT-cut crystal frequency change in the temperature range between 10 and 40 °C. The oscillator switching method and the switching impedances connected to the quartz crystal do not only compensate for the crystal's natural temperature characteristics but also any other influences on the crystal such as ageing as well as from other oscillating circuit elements. In addition, the method also improves frequency sensitivity in inductance measurements. The experimental results show that through high temperature compensation improvement of the quartz crystal characteristics, this switching method theoretically enables a 2 pH resolution. It converts inductance to frequency in the range of 85-100 µH to 2-560 kHz.

  6. High-Resolution Digital-to-Time Converter Implemented in an FPGA Chip

    Directory of Open Access Journals (Sweden)

    Hai Wang

    2017-01-01

    Full Text Available This paper presents the design and implementation of a new digital-to-time converter (DTC. The obtained resolution is 1.02 ps, and the dynamic range is about 590 ns. The experimental results indicate that the measured differential nonlinearity (DNL and integral nonlinearity (INL are −0.17~+0.13 LSB and −0.35~+0.62 LSB, respectively. This DTC builds coarse and fine Vernier delay lines constructed by programmable delay lines (PDLs to ensure high performance delay. Benefited by the close-loop feedback mechanism of the PDLs’ control module, the presented DTC has excellent voltage and temperature stability. What is more, the proposed DTC can be implemented in a single field programmable gate array (FPGA chip.

  7. A directly converting high-resolution intra-oral X-ray imaging sensor

    CERN Document Server

    Spartiotis, K; Schulman, T; Puhakka, K; Muukkonen, K

    2003-01-01

    A digital intra-oral X-ray imaging sensor with an active area of 3.6x2.9 cm sup 2 and consisting of six charge-integrating CMOS signal readout circuits bump bonded to one high-resistivity silicon pixel detector has been developed and tested. The pixel size is 35 mu m. The X-rays entering the sensor window are converted directly to electrical charge in the depleted detector material yielding minimum lateral signal spread and maximum image sharpness. The signal charge is collected on the gates of the input field effect transistors of the CMOS signal readout circuits. The analog signal readout is performed by multiplexing in the current mode independent of the signal charge collection enabling multiple readout cycles with negligible dead time and thus imaging with wide dynamic range. Since no intermediate conversion material of X-rays to visible light is needed, the sensor structure is very compact. The analog image signals are guided from the sensor output through a thin cable to signal processing, AD conversio...

  8. A high-resolution and one-cycle conversion time-to-digital converter architecture for PET image applications.

    Science.gov (United States)

    Sheng, Duo; Chung, Ching-Che; Huang, Chih-Chung; Jian, Jia-Wei

    2013-01-01

    In this paper, a high-resolution and one-cycle conversion time-to-digital converter (TDC) architecture with cell-based design for positron emission tomography (PET) applications is presented. The proposed TDC employs a cascade-stage structure to achieve high timing resolution and wide sampling range at the same time. Besides, based on the proposed two-level conversion structure, the proposed TDC not only can achieve single cycle latency and high speed of operation, but also have low circuit complexity as compared with conventional approaches. Simulation results show that operation frequency of the proposed TDC can be improved to 200 MHz with 50 ps resolution. In addition, the proposed TDC can be implemented with standard cells, making it easily portable to different processes and very suitable for biomedical chip applications.

  9. Implementation of a high resolution (< 11 ps RMS) Time-to-Digital Converter in a Field Programmable Gate Array

    Energy Technology Data Exchange (ETDEWEB)

    Ugur, Cahit [Helmholtz-Institut Mainz, Johannes Gutenberg-Universitaet Mainz (Germany); Bayer, Eugen [Department for Digital Electronics, University Kassel (Germany); Kurz, Nikolaus; Traxler, Michael [GSI Helmholtz Centre for Heavy Ion Research, Darmstadt (Germany); Michel, Jan [Institute for Nuclear Physics, Goethe University Frankfurt, Frankfurt am Main (Germany)

    2012-07-01

    A high resolution time-to-digital converter (TDC) was implemented in a general purpose field-programmable gate array (FPGA), a re-programmable digital chip. RMS and the time resolution of different channels are calculated for one clock cycle (5 ns) interval and a minimum of 10.3 ps RMS on two channels is achieved, which yields to a time resolution of 7.3 ps (10.3 ps/{radical}(2)) on a single channel. The TDC can be used in time-of-flight, time-over-threshold, drift time measurement applications as well as many other measurements with specific Front-End Electronics (FEE), e.g. charge measurements with charge-to-width (Q2W) FEE. The re-programmable flexibility of FPGAs also allows to have application specific features, e.g. trigger window, zero dead time etc.

  10. High-speed and high-resolution analog-to-digital and digital-to-analog converters

    NARCIS (Netherlands)

    van de Plassche, R.J.

    1989-01-01

    Analog-to-digital and digital-to-analog converters are important building blocks connecting the analog world of transducers with the digital world of computing, signal processing and data acquisition systems. In chapter two the converter as part of a system is described. Requirements of analog

  11. Compensation of multi-channel mismatches in high-speed high-resolution photonic analog-to-digital converter.

    Science.gov (United States)

    Yang, Guang; Zou, Weiwen; Yu, Lei; Wu, Kan; Chen, Jianping

    2016-10-17

    We demonstrate a method to compensate multi-channel mismatches that intrinsically exist in a photonic analog-to-digital converter (ADC) system. This system, nominated time-wavelength interleaved photonic ADC (TWI-PADC), is time-interleaved via wavelength demultiplexing/multiplexing before photonic sampling, wavelength demultiplexing channelization, and electronic quantization. Mismatches among multiple channels are estimated in frequency domain and hardware adjustment are used to approach the device-limited accuracy. A multi-channel mismatch compensation algorithm, inspired from the time-interleaved electronic ADC, is developed to effectively improve the performance of TWI-PADC. In the experiment, we configure out a 4-channel TWI-PADC system with 40 GS/s sampling rate based on a 10-GHz actively mode-locked fiber laser. After multi-channel mismatch compensation, the effective number of bit (ENOB) of the 40-GS/s TWI-PADC system is enhanced from ~6 bits to >8.5 bits when the RF frequency is within 0.1-3.1 GHz and from ~6 bits to >7.5 bits within 3.1-12.1 GHz. The enhanced performance of the TWI-PADC system approaches the limitation determined by the timing jitter and noise.

  12. An Accurate Timing Alignment Method with Time-to-Digital Converter Linearity Calibration for High-Resolution TOF PET.

    Science.gov (United States)

    Li, Hongdi; Wang, Chao; An, Shaohui; Lu, Xingyu; Dong, Yun; Liu, Shitao; Baghaei, Hossain; Zhang, Yuxuan; Ramirez, Rocio; Wong, Wai-Hoi

    2015-06-01

    Accurate PET system timing alignment minimizes the coincidence time window and therefore reduces random events and improves image quality. It is also critical for time-of-flight (TOF) image reconstruction. Here, we use a thin annular cylinder (shell) phantom filled with a radioactive source and located axially and centrally in a PET camera for the timing alignment of a TOF PET system. This timing alignment method involves measuring the time differences between the selected coincidence detector pairs, calibrating the differential and integral nonlinearity of the time-to-digital converter (TDC) with the same raw data and deriving the intrinsic time biases for each detector using an iterative algorithm. The raw time bias for each detector is downloaded to the front-end electronics and the residual fine time bias can be applied during the TOF list-mode reconstruction. Our results showed that a timing alignment accuracy of better than ±25 ps can be achieved, and a preliminary timing resolution of 473 ps (full width at half maximum) was measured in our prototype TOF PET/CT system.

  13. High-resolution W-band ISAR imaging system utilizing a logic-operation-based photonic digital-to-analog converter.

    Science.gov (United States)

    Peng, Shaowen; Li, Shangyuan; Xue, Xiaoxiao; Xiao, Xuedi; Wu, Dexin; Zheng, Xiaoping; Zhou, Bingkun

    2018-01-22

    W-band inverse synthetic aperture radar (ISAR) imaging systems are very useful for automatic target recognition and classification due to their high spatial resolution, high penetration and small antenna size. Broadband linear frequency modulated wave (LFMW) is usually applied to this system for its de-chirping characteristic. However, nearly all of the LFMW generated in electronic W-band ISAR system are based on multipliers and mixers, suffering seriously from electromagnetic interference (EMI) and timing jitter. And photonic-assisted LFMW generator reported before is always limited by bandwidth or time aperture. In this paper, for the first time, we propose and experimentally demonstrate a high-resolution W-band ISAR imaging system utilizing a novel logic-operation-based photonic digital-to-analog converter (LOPDAC). The equivalent sampling rate of the LOPDAC is twice as large as the rate of the digital driving signal. Thus, a broadband LFMW with a large time aperture can be generated by the LOPDAC. This LFMW is up-converted to W band with an optical frequency comb. After photonic-assisted de-chirping processing and data processing to the echo, a high-resolution two-dimension image can be obtained. Experimentally, W-band radar with a time-bandwidth product (TBWP) as large as 79200 (bandwidth 8 GHz; temporal duration 9.9 us) is established and investigated. Results show that the two-dimension (range and cross-range) imaging resolution is ~1.9 cm × ~1.6 cm with a sampling rate of 100 MSa/s in the receiver.

  14. Evaluation of Advanced Bionics high resolution mode.

    Science.gov (United States)

    Buechner, Andreas; Frohne-Buechner, Carolin; Gaertner, Lutz; Lesinski-Schiedat, Anke; Battmer, Rolf-Dieter; Lenarz, Thomas

    2006-07-01

    The objective of this paper is to evaluate the advantages of the Advanced Bionic high resolution mode for speech perception, through a retrospective analysis. Forty-five adult subjects were selected who had a minimum experience of three months' standard mode (mean of 10 months) before switching to high resolution mode. Speech perception was tested in standard mode immediately before fitting with high resolution mode, and again after a maximum of six months high resolution mode usage (mean of two months). A significant improvement was found, between 11 and 17%, depending on the test material. The standard mode preference does not give any indication about the improvement when switching to high resolution. Users who are converted within any study achieve a higher performance improvement than those converted in the clinical routine. This analysis proves the significant benefits of high resolution mode for users, and also indicates the need for guidelines for individual optimization of parameter settings in a high resolution mode program.

  15. High Resolution Elevation Contours

    Data.gov (United States)

    Minnesota Department of Natural Resources — This dataset contains contours generated from high resolution data sources such as LiDAR. Generally speaking this data is 2 foot or less contour interval.

  16. Ultra high resolution tomography

    Energy Technology Data Exchange (ETDEWEB)

    Haddad, W.S.

    1994-11-15

    Recent work and results on ultra high resolution three dimensional imaging with soft x-rays will be presented. This work is aimed at determining microscopic three dimensional structure of biological and material specimens. Three dimensional reconstructed images of a microscopic test object will be presented; the reconstruction has a resolution on the order of 1000 A in all three dimensions. Preliminary work with biological samples will also be shown, and the experimental and numerical methods used will be discussed.

  17. A Portable, High Resolution, Surface Measurement Device

    Science.gov (United States)

    Ihlefeld, Curtis M.; Burns, Bradley M.; Youngquist, Robert C.

    2012-01-01

    A high resolution, portable, surface measurement device has been demonstrated to provide micron-resolution topographical plots. This device was specifically developed to allow in-situ measurements of defects on the Space Shuttle Orbiter windows, but is versatile enough to be used on a wide variety of surfaces. This paper discusses the choice of an optical sensor and then the decisions required to convert a lab bench optical measurement device into an ergonomic portable system. The necessary trade-offs between performance and portability are presented along with a description of the device developed to measure Orbiter window defects.

  18. Improved methods for high resolution electron microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Taylor, J.R.

    1987-04-01

    Existing methods of making support films for high resolution transmission electron microscopy are investigated and novel methods are developed. Existing methods of fabricating fenestrated, metal reinforced specimen supports (microgrids) are evaluated for their potential to reduce beam induced movement of monolamellar crystals of C/sub 44/H/sub 90/ paraffin supported on thin carbon films. Improved methods of producing hydrophobic carbon films by vacuum evaporation, and improved methods of depositing well ordered monolamellar paraffin crystals on carbon films are developed. A novel technique for vacuum evaporation of metals is described which is used to reinforce microgrids. A technique is also developed to bond thin carbon films to microgrids with a polymer bonding agent. Unique biochemical methods are described to accomplish site specific covalent modification of membrane proteins. Protocols are given which covalently convert the carboxy terminus of papain cleaved bacteriorhodopsin to a free thiol. 53 refs., 19 figs., 1 tab.

  19. High-resolution multiphoton cryomicroscopy.

    Science.gov (United States)

    König, Karsten; Uchugonova, Aisada; Breunig, Hans Georg

    2014-03-15

    An ultracompact high-resolution multiphoton cryomicroscope with a femtosecond near infrared fiber laser has been utilized to study the cellular autofluorescence during freezing and thawing of cells. Cooling resulted in an increase of the intracellular fluorescence intensity followed by morphological modifications at temperatures below -10 °C, depending on the application of the cryoprotectant DMSO and the cooling rate. Furthermore, fluorescence lifetime imaging revealed an increase of the mean lifetime with a decrease in temperature. Non-destructive, label-free optical biopsies of biomaterial in ice can be obtained with sub-20 mW mean powers. Copyright © 2013 Elsevier Inc. All rights reserved.

  20. Enhanced High Resolution RBS System

    Science.gov (United States)

    Pollock, Thomas J.; Hass, James A.; Klody, George M.

    2011-06-01

    Improvements in full spectrum resolution with the second NEC high resolution RBS system are summarized. Results for 50 Å TiN/HfO films on Si yielding energy resolution on the order of 1 keV are also presented. Detector enhancements include improved pulse processing electronics, upgraded shielding for the MCP/RAE detector, and reduced noise generated from pumping. Energy resolution measurements on spectra front edge coupled with calculations using 0.4mStr solid angle show that beam energy spread at 400 KeV from the Pelletron® accelerator is less than 100 eV. To improve user throughput, magnet control has been added to the automatic data collection. Depth profiles derived from experimental data are discussed. For the thin films profiled, depth resolutions were on the Angstrom level with the non-linear energy/channel conversions ranging from 100 to 200 eV.

  1. High resolution tomographic instrument development

    Energy Technology Data Exchange (ETDEWEB)

    1992-01-01

    Our recent work has concentrated on the development of high-resolution PET instrumentation reflecting in part the growing importance of PET in nuclear medicine imaging. We have developed a number of positron imaging instruments and have the distinction that every instrument has been placed in operation and has had an extensive history of application for basic research and clinical study. The present program is a logical continuation of these earlier successes. PCR-I, a single ring positron tomograph was the first demonstration of analog coding using BGO. It employed 4 mm detectors and is currently being used for a wide range of biological studies. These are of immense importance in guiding the direction for future instruments. In particular, PCR-II, a volume sensitive positron tomograph with 3 mm spatial resolution has benefited greatly from the studies using PCR-I. PCR-II is currently in the final stages of assembly and testing and will shortly be placed in operation for imaging phantoms, animals and ultimately humans. Perhaps the most important finding resulting from our previous study is that resolution and sensitivity must be carefully balanced to achieve a practical high resolution system. PCR-II has been designed to have the detection characteristics required to achieve 3 mm resolution in human brain under practical imaging situations. The development of algorithms by the group headed by Dr. Chesler is based on a long history of prior study including his joint work with Drs. Pelc and Reiderer and Stearns. This body of expertise will be applied to the processing of data from PCR-II when it becomes operational.

  2. High resolution tomographic instrument development

    Energy Technology Data Exchange (ETDEWEB)

    1992-08-01

    Our recent work has concentrated on the development of high-resolution PET instrumentation reflecting in part the growing importance of PET in nuclear medicine imaging. We have developed a number of positron imaging instruments and have the distinction that every instrument has been placed in operation and has had an extensive history of application for basic research and clinical study. The present program is a logical continuation of these earlier successes. PCR-I, a single ring positron tomograph was the first demonstration of analog coding using BGO. It employed 4 mm detectors and is currently being used for a wide range of biological studies. These are of immense importance in guiding the direction for future instruments. In particular, PCR-II, a volume sensitive positron tomograph with 3 mm spatial resolution has benefited greatly from the studies using PCR-I. PCR-II is currently in the final stages of assembly and testing and will shortly be placed in operation for imaging phantoms, animals and ultimately humans. Perhaps the most important finding resulting from our previous study is that resolution and sensitivity must be carefully balanced to achieve a practical high resolution system. PCR-II has been designed to have the detection characteristics required to achieve 3 mm resolution in human brain under practical imaging situations. The development of algorithms by the group headed by Dr. Chesler is based on a long history of prior study including his joint work with Drs. Pelc and Reiderer and Stearns. This body of expertise will be applied to the processing of data from PCR-II when it becomes operational.

  3. High-resolution infrared imaging

    Science.gov (United States)

    Falco, Charles M.

    2010-08-01

    The hands and mind of an artist are intimately involved in the creative process of image formation, intrinsically making paintings significantly more complex than photographs to analyze. In spite of this difficulty, several years ago the artist David Hockney and I identified optical evidence within a number of paintings that demonstrated artists began using optical projections as early as c1425 - nearly 175 years before Galileo - as aids for producing portions of their images. In the course of our work, Hockney and I developed insights that I have been applying to a new approach to computerized image analysis. Recently I developed and characterized a portable high resolution infrared for capturing additional information from paintings. Because many pigments are semi-transparent in the IR, in a number of cases IR photographs ("reflectograms") have revealed marks made by the artists that had been hidden under paint ever since they were made. I have used this IR camera to capture photographs ("reflectograms") of hundreds of paintings in over a dozen museums on three continents and, in some cases, these reflectograms have provided new insights into decisions the artists made in creating the final images that we see in the visible.

  4. Section on High Resolution Optical Imaging (HROI)

    Data.gov (United States)

    Federal Laboratory Consortium — The Section on High Resolution Optical Imaging (HROI) develops novel technologies for studying biological processes at unprecedented speed and resolution. Research...

  5. VT Hydrography Dataset - High Resolution NHD

    Data.gov (United States)

    Vermont Center for Geographic Information — (Link to Metadata) The Vermont Hydrography Dataset (VHD) is compliant with the local resolution (also known as High Resolution) National Hydrography Dataset (NHD)...

  6. High Resolution Silicon Deformable Mirrors Project

    Data.gov (United States)

    National Aeronautics and Space Administration — In this proposal we describe a plan to build a deformable mirror suitable for space-based operation in systems for high-resolution imaging. The prototype DM will be...

  7. High Resolution Silicon Deformable Mirrors Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This proposal describes a plan to build a prototype small stroke, high precision deformable mirror suitable for space-based operation in systems for high-resolution...

  8. Structure of high-resolution NMR spectra

    CERN Document Server

    Corio, PL

    2012-01-01

    Structure of High-Resolution NMR Spectra provides the principles, theories, and mathematical and physical concepts of high-resolution nuclear magnetic resonance spectra.The book presents the elementary theory of magnetic resonance; the quantum mechanical theory of angular momentum; the general theory of steady state spectra; and multiple quantum transitions, double resonance and spin echo experiments.Physicists, chemists, and researchers will find the book a valuable reference text.

  9. Using Adobe Acrobat to create high-resolution line art images.

    Science.gov (United States)

    Woo, Hyoun Sik; Lee, Jeong Min

    2009-08-01

    The purpose of this article is to introduce a method for using Adobe Acrobat to make high-resolution and high-quality line art images. High-resolution and high-quality line art images for radiology journal submission can be generated using Adobe Acrobat as a steppingstone, and the customized PDF conversion settings can be used for converting hybrid images, including both bitmap and vector components.

  10. Qualitative interpretation of high resolution aeromagnetic (HRAM ...

    African Journals Online (AJOL)

    Qualitative interpretation of high resolution aeromagnetic (HRAM) data from some parts of offshore Niger delta, Nigeria. ... Open Access DOWNLOAD FULL TEXT ... The original raster map, obtained from the Nigeria Geological Survey Agency (NGSA) in half degree sheet, was subjected to qualitative data analysis using the ...

  11. A High-Resolution Stopwatch for Cents

    Science.gov (United States)

    Gingl, Z.; Kopasz, K.

    2011-01-01

    A very low-cost, easy-to-make stopwatch is presented to support various experiments in mechanics. The high-resolution stopwatch is based on two photodetectors connected directly to the microphone input of a sound card. Dedicated free open-source software has been developed and made available to download. The efficiency is demonstrated by a free…

  12. Compressive sensing for high resolution radar imaging

    NARCIS (Netherlands)

    Anitori, L.; Otten, M.P.G.; Hoogeboom, P.

    2010-01-01

    In this paper we present some preliminary results on the application of Compressive Sensing (CS) to high resolution radar imaging. CS is a recently developed theory which allows reconstruction of sparse signals with a number of measurements much lower than what is required by the Shannon sampling

  13. Compact high-resolution spectral phase shaper

    NARCIS (Netherlands)

    Postma, S.; van der Walle, P.; Offerhaus, Herman L.; van Hulst, N.F.

    2005-01-01

    The design and operation of a high-resolution spectral phase shaper with a footprint of only 7×10 cm2 is presented. The liquid-crystal modulator has 4096 elements. More than 600 independent degrees of freedom can be positioned with a relative accuracy of 1 pixel. The spectral shaping of pulses from

  14. High resolution analysis of interphase chromosome domains

    NARCIS (Netherlands)

    Visser, A. E.; Jaunin, F.; Fakan, S.; Aten, J. A.

    2000-01-01

    Chromosome territories need to be well defined at high resolution before functional aspects of chromosome organization in interphase can be explored. To visualize chromosomes by electron microscopy (EM), the DNA of Chinese hamster fibroblasts was labeled in vivo with thymidine analogue BrdU. Labeled

  15. High resolution technology for FPD lithography tools

    Science.gov (United States)

    Yabu, Nobuhiko; Nagai, Yoshiyuki; Tomura, Satoshi; Yoshikawa, Tomohiro

    2013-06-01

    As the resolution of LCD panels adapted for Smartphone and Tablet PC rapidly becomes higher, the performance needed for lithography tools to produce them also becomes higher than ever. To respond to such needs, we have developed new lithography tools for mass production of high resolution LCD panels. We have executed various exposure tests to evaluate their performance. In this paper, we present the results of these tests. By employing higher NA projection optics, high resolution (2.0μm and under) has been achieved. We also present the effect of special illumination and the difference in profile between kinds of photoresist. Furthermore, we also refer what will be needed for masks and blanks in the next generation. To achieve even higher resolution, it is necessary for masks and blanks to have high flatness, low level of defects and small linewidth error.

  16. Radiation length imaging with high resolution telescopes

    OpenAIRE

    Stolzenberg, U.; Frey, A.; Schwenker, B; Wieduwilt, P.; Marinas, C; Lütticke, F.

    2016-01-01

    The construction of low mass vertex detectors with a high level of system integration is of great interest for next generation collider experiments. Radiation length images with a sufficient spatial resolution can be used to measure and disentangle complex radiation length $X$/$X_0$ profiles and contribute to the understanding of vertex detector systems. Test beam experiments with multi GeV particle beams and high-resolution tracking telescopes provide an opportunity to obtain precise 2D imag...

  17. High Resolution Spectra of HE Detonations

    Science.gov (United States)

    1980-07-07

    region. We shall assume for present purposes that the emissivity of the detonation products of a 50 to 100 lb HE explosion is also in the viciity of... speed . Incorporated in the emulsion layers are dye forming coup- lers which react simultaneously during I , developmentto produce a separate dye S...Best Available Cop 1~EV~ AFTAC-TR-80-24 HIGH RESOLUTION SPECTRA OF HE DETONATIONS HSS Inc 2 Alfred Circle Bedford, MA 01730 7 JULY 1980 AUG 4 9D

  18. High resolution NMR theory and chemical applications

    CERN Document Server

    Becker, Edwin D

    1969-01-01

    High Resolution NMR: Theory and Chemical Applications focuses on the applications of nuclear magnetic resonance (NMR), as well as chemical shifts, lattices, and couplings. The book first offers information on the theory of NMR, including nuclear spin and magnetic moment, spin lattice relaxation, line widths, saturation, quantum mechanical description of NMR, and ringing. The text then ponders on instrumentation and techniques and chemical shifts. Discussions focus on the origin of chemical shifts, reference compounds, empirical correlations of chemical shifts, modulation and phase detection,

  19. Ultra-high resolution coded wavefront sensor

    KAUST Repository

    Wang, Congli

    2017-06-08

    Wavefront sensors and more general phase retrieval methods have recently attracted a lot of attention in a host of application domains, ranging from astronomy to scientific imaging and microscopy. In this paper, we introduce a new class of sensor, the Coded Wavefront Sensor, which provides high spatio-temporal resolution using a simple masked sensor under white light illumination. Specifically, we demonstrate megapixel spatial resolution and phase accuracy better than 0.1 wavelengths at reconstruction rates of 50 Hz or more, thus opening up many new applications from high-resolution adaptive optics to real-time phase retrieval in microscopy.

  20. High resolution extremity CT for biomechanics modeling

    Energy Technology Data Exchange (ETDEWEB)

    Ashby, A.E.; Brand, H.; Hollerbach, K.; Logan, C.M.; Martz, H.E.

    1995-09-23

    With the advent of ever more powerful computing and finite element analysis (FEA) capabilities, the bone and joint geometry detail available from either commercial surface definitions or from medical CT scans is inadequate. For dynamic FEA modeling of joints, precise articular contours are necessary to get appropriate contact definition. In this project, a fresh cadaver extremity was suspended in parafin in a lucite cylinder and then scanned with an industrial CT system to generate a high resolution data set for use in biomechanics modeling.

  1. Detailed mitochondrial phenotyping by high resolution metabolomics.

    Directory of Open Access Journals (Sweden)

    James R Roede

    Full Text Available Mitochondrial phenotype is complex and difficult to define at the level of individual cell types. Newer metabolic profiling methods provide information on dozens of metabolic pathways from a relatively small sample. This pilot study used "top-down" metabolic profiling to determine the spectrum of metabolites present in liver mitochondria. High resolution mass spectral analyses and multivariate statistical tests provided global metabolic information about mitochondria and showed that liver mitochondria possess a significant phenotype based on gender and genotype. The data also show that mitochondria contain a large number of unidentified chemicals.

  2. High-Resolution PET Detector. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Karp, Joel

    2014-03-26

    The objective of this project was to develop an understanding of the limits of performance for a high resolution PET detector using an approach based on continuous scintillation crystals rather than pixelated crystals. The overall goal was to design a high-resolution detector, which requires both high spatial resolution and high sensitivity for 511 keV gammas. Continuous scintillation detectors (Anger cameras) have been used extensively for both single-photon and PET scanners, however, these instruments were based on NaI(Tl) scintillators using relatively large, individual photo-multipliers. In this project we investigated the potential of this type of detector technology to achieve higher spatial resolution through the use of improved scintillator materials and photo-sensors, and modification of the detector surface to optimize the light response function.We achieved an average spatial resolution of 3-mm for a 25-mm thick, LYSO continuous detector using a maximum likelihood position algorithm and shallow slots cut into the entrance surface.

  3. Principles of high resolution NMR in solids

    CERN Document Server

    Mehring, Michael

    1983-01-01

    The field of Nuclear Magnetic Resonance (NMR) has developed at a fascinating pace during the last decade. It always has been an extremely valuable tool to the organic chemist by supplying molecular "finger print" spectra at the atomic level. Unfortunately the high resolution achievable in liquid solutions could not be obtained in solids and physicists and physical chemists had to live with unresolved lines open to a wealth of curve fitting procedures and a vast amount of speculations. High resolution NMR in solids seemed to be a paradoxon. Broad structure­ less lines are usually encountered when dealing with NMR in solids. Only with the recent advent of mUltiple pulse, magic angle, cross-polarization, two-dimen­ sional and multiple-quantum spectroscopy and other techniques during the last decade it became possible to resolve finer details of nuclear spin interactions in solids. I have felt that graduate students, researchers and others beginning to get involved with these techniques needed a book which trea...

  4. Limiting liability via high resolution image processing

    Energy Technology Data Exchange (ETDEWEB)

    Greenwade, L.E.; Overlin, T.K.

    1996-12-31

    The utilization of high resolution image processing allows forensic analysts and visualization scientists to assist detectives by enhancing field photographs, and by providing the tools and training to increase the quality and usability of field photos. Through the use of digitized photographs and computerized enhancement software, field evidence can be obtained and processed as `evidence ready`, even in poor lighting and shadowed conditions or darkened rooms. These images, which are most often unusable when taken with standard camera equipment, can be shot in the worst of photographic condition and be processed as usable evidence. Visualization scientists have taken the use of digital photographic image processing and moved the process of crime scene photos into the technology age. The use of high resolution technology will assist law enforcement in making better use of crime scene photography and positive identification of prints. Valuable court room and investigation time can be saved and better served by this accurate, performance based process. Inconclusive evidence does not lead to convictions. Enhancement of the photographic capability helps solve one major problem with crime scene photos, that if taken with standard equipment and without the benefit of enhancement software would be inconclusive, thus allowing guilty parties to be set free due to lack of evidence.

  5. High-Resolution Scintimammography: A Pilot Study

    Energy Technology Data Exchange (ETDEWEB)

    Rachel F. Brem; Joelle M. Schoonjans; Douglas A. Kieper; Stan Majewski; Steven Goodman; Cahid Civelek

    2002-07-01

    This study evaluated a novel high-resolution breast-specific gamma camera (HRBGC) for the detection of suggestive breast lesions. Methods: Fifty patients (with 58 breast lesions) for whom a scintimammogram was clinically indicated were prospectively evaluated with a general-purpose gamma camera and a novel HRBGC prototype. The results of conventional and high-resolution nuclear studies were prospectively classified as negative (normal or benign) or positive (suggestive or malignant) by 2 radiologists who were unaware of the mammographic and histologic results. All of the included lesions were confirmed by pathology. Results: There were 30 benign and 28 malignant lesions. The sensitivity for detection of breast cancer was 64.3% (18/28) with the conventional camera and 78.6% (22/28) with the HRBGC. The specificity with both systems was 93.3% (28/30). For the 18 nonpalpable lesions, sensitivity was 55.5% (10/18) and 72.2% (13/18) with the general-purpose camera and the HRBGC, respectively. For lesions 1 cm, 7 of 15 were detected with the general-purpose camera and 10 of 15 with the HRBGC. Four lesions (median size, 8.5 mm) were detected only with the HRBGC and were missed by the conventional camera. Conclusion: Evaluation of indeterminate breast lesions with an HRBGC results in improved sensitivity for the detection of cancer, with greater improvement shown for nonpalpable and 1-cm lesions.

  6. High-Resolution Broadband Spectral Interferometry

    Energy Technology Data Exchange (ETDEWEB)

    Erskine, D J; Edelstein, J

    2002-08-09

    We demonstrate solar spectra from a novel interferometric method for compact broadband high-resolution spectroscopy. The spectral interferometer (SI) is a hybrid instrument that uses a spectrometer to externally disperse the output of a fixed-delay interferometer. It also has been called an externally dispersed interferometer (EDI). The interferometer can be used with linear spectrometers for imaging spectroscopy or with echelle spectrometers for very broad-band coverage. EDI's heterodyning technique enhances the spectrometer's response to high spectral-density features, increasing the effective resolution by factors of several while retaining its bandwidth. The method is extremely robust to instrumental insults such as focal spot size or displacement. The EDI uses no moving parts, such as purely interferometric FTS spectrometers, and can cover a much wider simultaneous bandpass than other internally dispersed interferometers (e.g. HHS or SHS).

  7. Development of New High Resolution Neutron Detector

    Science.gov (United States)

    Mostella, L. D., III; Rajabali, M.; Loureiro, D. P.; Grzywacz, R.

    2017-09-01

    Beta-delayed neutron emission is a prevalent form of decay for neutron-rich nuclei. This occurs when an unstable nucleus undergoes beta decay, but produces a daughter nucleus in an excited state above the neutron separation energy. The daughter nucleus then de-excites by ejecting one or more neutrons. We wish to map the states from which these nuclei decay via neutron spectroscopy using NEXT, a new high resolution neutron detector. NEXT utilizes silicon photomultipliers and 6 mm thick pulse-shape discriminating plastic scintillators, allowing for smaller and more compact modular geometries in the NEXT array. Timing measurements for the detector were performed and a resolution of 893 ps (FWHM) has been achieved so far. Aspects of the detector that were investigated and will be presented here include scintillator geometry, wrapping materials, fitting functions for the digitized signals, and electronic components coupled to the silicon photomultipliers for signal shaping.

  8. High Resolution, High Frame Rate Video Technology

    Science.gov (United States)

    1990-01-01

    Papers and working group summaries presented at the High Resolution, High Frame Rate Video (HHV) Workshop are compiled. HHV system is intended for future use on the Space Shuttle and Space Station Freedom. The Workshop was held for the dual purpose of: (1) allowing potential scientific users to assess the utility of the proposed system for monitoring microgravity science experiments; and (2) letting technical experts from industry recommend improvements to the proposed near-term HHV system. The following topics are covered: (1) State of the art in the video system performance; (2) Development plan for the HHV system; (3) Advanced technology for image gathering, coding, and processing; (4) Data compression applied to HHV; (5) Data transmission networks; and (6) Results of the users' requirements survey conducted by NASA.

  9. High Resolution Regional Climate Simulations over Alaska

    Science.gov (United States)

    Monaghan, A. J.; Clark, M. P.; Arnold, J.; Newman, A. J.; Musselman, K. N.; Barlage, M. J.; Xue, L.; Liu, C.; Gutmann, E. D.; Rasmussen, R.

    2016-12-01

    In order to appropriately plan future projects to build and maintain infrastructure (e.g., dams, dikes, highways, airports), a number of U.S. federal agencies seek to better understand how hydrologic regimes may shift across the country due to climate change. Building on the successful completion of a series of high-resolution WRF simulations over the Colorado River Headwaters and contiguous USA, our team is now extending these simulations over the challenging U.S. States of Alaska and Hawaii. In this presentation we summarize results from a newly completed 4-km resolution WRF simulation over Alaska spanning 2002-2016 at 4-km spatial resolution. Our aim is to gain insight into the thermodynamics that drive key precipitation processes, particularly the extremes that are most damaging to infrastructure.

  10. Constructing a WISE High Resolution Galaxy Atlas

    Science.gov (United States)

    Jarrett, T. H.; Masci, F.; Tsai, C. W.; Petty, S.; Cluver, M.; Assef, Roberto J.; Benford, D.; Blain, A.; Bridge, C.; Donoso, E.; hide

    2012-01-01

    After eight months of continuous observations, the Wide-field Infrared Survey Explorer (WISE) mapped the entire sky at 3.4 micron, 4.6 micron, 12 micron, and 22 micron. We have begun a dedicated WISE High Resolution Galaxy Atlas project to fully characterize large, nearby galaxies and produce a legacy image atlas and source catalog. Here we summarize the deconvolution techniques used to significantly improve the spatial resolution of WISE imaging, specifically designed to study the internal anatomy of nearby galaxies. As a case study, we present results for the galaxy NGC 1566, comparing the WISE enhanced-resolution image processing to that of Spitzer, Galaxy Evolution Explorer, and ground-based imaging. This is the first paper in a two-part series; results for a larger sample of nearby galaxies are presented in the second paper.

  11. High-Resolution Movement EEG Classification

    Directory of Open Access Journals (Sweden)

    Jakub Štastný

    2007-01-01

    Full Text Available The aim of the contribution is to analyze possibilities of high-resolution movement classification using human EEG. For this purpose, a database of the EEG recorded during right-thumb and little-finger fast flexion movements of the experimental subjects was created. The statistical analysis of the EEG was done on the subject's basis instead of the commonly used grand averaging. Statistically significant differences between the EEG accompanying movements of both fingers were found, extending the results of other so far published works. The classifier based on hidden Markov models was able to distinguish between movement and resting states (classification score of 94–100%, but it was unable to recognize the type of the movement. This is caused by the large fraction of other (nonmovement related EEG activities in the recorded signals. A classification method based on advanced EEG signal denoising is being currently developed to overcome this problem.

  12. High resolution multimodal clinical ophthalmic imaging system.

    Science.gov (United States)

    Mujat, Mircea; Ferguson, R Daniel; Patel, Ankit H; Iftimia, Nicusor; Lue, Niyom; Hammer, Daniel X

    2010-05-24

    We developed a multimodal adaptive optics (AO) retinal imager which is the first to combine high performance AO-corrected scanning laser ophthalmoscopy (SLO) and swept source Fourier domain optical coherence tomography (SSOCT) imaging modes in a single compact clinical prototype platform. Such systems are becoming ever more essential to vision research and are expected to prove their clinical value for diagnosis of retinal diseases, including glaucoma, diabetic retinopathy (DR), age-related macular degeneration (AMD), and retinitis pigmentosa. The SSOCT channel operates at a wavelength of 1 microm for increased penetration and visualization of the choriocapillaris and choroid, sites of major disease activity for DR and wet AMD. This AO system is designed for use in clinical populations; a dual deformable mirror (DM) configuration allows simultaneous low- and high-order aberration correction over a large range of refractions and ocular media quality. The system also includes a wide field (33 deg.) line scanning ophthalmoscope (LSO) for initial screening, target identification, and global orientation, an integrated retinal tracker (RT) to stabilize the SLO, OCT, and LSO imaging fields in the presence of lateral eye motion, and a high-resolution LCD-based fixation target for presentation of visual cues. The system was tested in human subjects without retinal disease for performance optimization and validation. We were able to resolve and quantify cone photoreceptors across the macula to within approximately 0.5 deg (approximately 100-150 microm) of the fovea, image and delineate ten retinal layers, and penetrate to resolve features deep into the choroid. The prototype presented here is the first of a new class of powerful flexible imaging platforms that will provide clinicians and researchers with high-resolution, high performance adaptive optics imaging to help guide therapies, develop new drugs, and improve patient outcomes.

  13. High-resolution transcriptome of human macrophages.

    Directory of Open Access Journals (Sweden)

    Marc Beyer

    Full Text Available Macrophages are dynamic cells integrating signals from their microenvironment to develop specific functional responses. Although, microarray-based transcriptional profiling has established transcriptional reprogramming as an important mechanism for signal integration and cell function of macrophages, current knowledge on transcriptional regulation of human macrophages is far from complete. To discover novel marker genes, an area of great need particularly in human macrophage biology but also to generate a much more thorough transcriptome of human M1- and M1-like macrophages, we performed RNA sequencing (RNA-seq of human macrophages. Using this approach we can now provide a high-resolution transcriptome profile of human macrophages under classical (M1-like and alternative (M2-like polarization conditions and demonstrate a dynamic range exceeding observations obtained by previous technologies, resulting in a more comprehensive understanding of the transcriptome of human macrophages. Using this approach, we identify important gene clusters so far not appreciated by standard microarray techniques. In addition, we were able to detect differential promoter usage, alternative transcription start sites, and different coding sequences for 57 gene loci in human macrophages. Moreover, this approach led to the identification of novel M1-associated (CD120b, TLR2, SLAMF7 as well as M2-associated (CD1a, CD1b, CD93, CD226 cell surface markers. Taken together, these data support that high-resolution transcriptome profiling of human macrophages by RNA-seq leads to a better understanding of macrophage function and will form the basis for a better characterization of macrophages in human health and disease.

  14. High-Resolution Transcriptome of Human Macrophages

    Science.gov (United States)

    Xue, Jia; Staratschek-Jox, Andrea; Vorholt, Daniela; Krebs, Wolfgang; Sommer, Daniel; Sander, Jil; Mertens, Christina; Nino-Castro, Andrea; Schmidt, Susanne V.; Schultze, Joachim L.

    2012-01-01

    Macrophages are dynamic cells integrating signals from their microenvironment to develop specific functional responses. Although, microarray-based transcriptional profiling has established transcriptional reprogramming as an important mechanism for signal integration and cell function of macrophages, current knowledge on transcriptional regulation of human macrophages is far from complete. To discover novel marker genes, an area of great need particularly in human macrophage biology but also to generate a much more thorough transcriptome of human M1- and M1-like macrophages, we performed RNA sequencing (RNA-seq) of human macrophages. Using this approach we can now provide a high-resolution transcriptome profile of human macrophages under classical (M1-like) and alternative (M2-like) polarization conditions and demonstrate a dynamic range exceeding observations obtained by previous technologies, resulting in a more comprehensive understanding of the transcriptome of human macrophages. Using this approach, we identify important gene clusters so far not appreciated by standard microarray techniques. In addition, we were able to detect differential promoter usage, alternative transcription start sites, and different coding sequences for 57 gene loci in human macrophages. Moreover, this approach led to the identification of novel M1-associated (CD120b, TLR2, SLAMF7) as well as M2-associated (CD1a, CD1b, CD93, CD226) cell surface markers. Taken together, these data support that high-resolution transcriptome profiling of human macrophages by RNA-seq leads to a better understanding of macrophage function and will form the basis for a better characterization of macrophages in human health and disease. PMID:23029029

  15. Integrated High Resolution Monitoring of Mediterranean vegetation

    Science.gov (United States)

    Cesaraccio, Carla; Piga, Alessandra; Ventura, Andrea; Arca, Angelo; Duce, Pierpaolo; Mereu, Simone

    2017-04-01

    The study of the vegetation features in a complex and highly vulnerable ecosystems, such as Mediterranean maquis, leads to the need of using continuous monitoring systems at high spatial and temporal resolution, for a better interpretation of the mechanisms of phenological and eco-physiological processes. Near-surface remote sensing techniques are used to quantify, at high temporal resolution, and with a certain degree of spatial integration, the seasonal variations of the surface optical and radiometric properties. In recent decades, the design and implementation of global monitoring networks involved the use of non-destructive and/or cheaper approaches such as (i) continuous surface fluxes measurement stations, (ii) phenological observation networks, and (iii) measurement of temporal and spatial variations of the vegetation spectral properties. In this work preliminary results from the ECO-SCALE (Integrated High Resolution Monitoring of Mediterranean vegetation) project are reported. The project was manly aimed to develop an integrated system for environmental monitoring based on digital photography, hyperspectral radiometry , and micrometeorological techniques during three years of experimentation (2013-2016) in a Mediterranean site of Italy (Capo Caccia, Alghero). The main results concerned the analysis of chromatic coordinates indices from digital images, to characterized the phenological patterns for typical shrubland species, determining start and duration of the growing season, and the physiological status in relation to different environmental drought conditions; then the seasonal patterns of canopy phenology, was compared to NEE (Net Ecosystem Exchange) patterns, showing similarities. However, maximum values of NEE and ER (Ecosystem respiration), and short term variation, seemed mainly tuned by inter annual pattern of meteorological variables, in particular of temperature recorded in the months preceding the vegetation green-up. Finally, green signals

  16. Superconducting High Resolution Fast-Neutron Spectrometers

    Energy Technology Data Exchange (ETDEWEB)

    Hau, Ionel Dragos [Univ. of California, Berkeley, CA (United States)

    2006-01-01

    Superconducting high resolution fast-neutron calorimetric spectrometers based on 6LiF and TiB{sub 2} absorbers have been developed. These novel cryogenic spectrometers measure the temperature rise produced in exothermal (n, α) reactions with fast neutrons in 6Li and 10B-loaded materials with heat capacity C operating at temperatures T close to 0.1 K. Temperature variations on the order of 0.5 mK are measured with a Mo/Cu thin film multilayer operated in the transition region between its superconducting and its normal state. The advantage of calorimetry for high resolution spectroscopy is due to the small phonon excitation energies kBT on the order of μeV that serve as signal carriers, resulting in an energy resolution ΔE ~ (kBT2C)1/2, which can be well below 10 keV. An energy resolution of 5.5 keV has been obtained with a Mo/Cu superconducting sensor and a TiB2 absorber using thermal neutrons from a 252Cf neutron source. This resolution is sufficient to observe the effect of recoil nuclei broadening in neutron spectra, which has been related to the lifetime of the first excited state in 7Li. Fast-neutron spectra obtained with a 6Li-enriched LiF absorber show an energy resolution of 16 keV FWHM, and a response in agreement with the 6Li(n, α)3H reaction cross section and Monte Carlo simulations for energies up to several MeV. The energy resolution of order of a few keV makes this novel instrument applicable to fast-neutron transmission spectroscopy based on the unique elemental signature provided by the neutron absorption and scattering resonances. The optimization of the energy resolution based on analytical and numerical models of the detector response is discussed in the context of these applications.

  17. High resolution measurement of the glycolytic rate

    Directory of Open Access Journals (Sweden)

    Carla X Bittner

    2010-09-01

    Full Text Available The glycolytic rate is sensitive to physiological activity, hormones, stress, aging and malignant transformation. Standard techniques to measure the glycolytic rate are based on radioactive isotopes, are not able to resolve single cells and have poor temporal resolution, limitations that hamper the study of energy metabolism in the brain and other organs. A new method is described in this article, which makes use of a recently-developed FRET glucose nanosensor to measure the rate of glycolysis in single cells with high temporal resolution. Used in cultured astrocytes, the method showed for the first time that glycolysis can be activated within seconds by a combination of glutamate and K+, supporting a role for astrocytes in neurometabolic and neurovascular coupling in the brain. It was also possible to make a direct comparison of metabolism in neurons and astrocytes lying in close proximity, paving the way to a high-resolution characterization of brain energy metabolism. Single-cell glycolytic rates were also measured in fibroblasts, adipocytes, myoblasts and tumor cells, showing higher rates for undifferentiated cells and significant metabolic heterogeneity within cell types. This method should facilitate the investigation of tissue metabolism at the single-cell level and is readily adaptable for high-throughput analysis.

  18. High resolution quantum metrology via quantum interpolation

    Science.gov (United States)

    Ajoy, Ashok; Liu, Yixiang; Saha, Kasturi; Marseglia, Luca; Jaskula, Jean-Christophe; Cappellaro, Paola

    2016-05-01

    Nitrogen Vacancy (NV) centers in diamond are a promising platform for quantum metrology - in particular for nanoscale magnetic resonance imaging to determine high resolution structures of single molecules placed outside the diamond. The conventional technique for sensing of external nuclear spins involves monitoring the effects of the target nuclear spins on the NV center coherence under dynamical decoupling (the CPMG/XY8 pulse sequence). However, the nuclear spin affects the NV coherence only at precise free evolution times - and finite timing resolution set by hardware often severely limits the sensitivity and resolution of the method. In this work, we overcome this timing resolution barrier by developing a technique to supersample the metrology signal by effectively implementing a quantum interpolation of the spin system dynamics. This method will enable spin sensing at high magnetic fields and high repetition rate, allowing significant improvements in sensitivity and spectral resolution. We experimentally demonstrate a resolution boost by over a factor of 100 for spin sensing and AC magnetometry. The method is shown to be robust, versatile to sensing normal and spurious signal harmonics, and ultimately limited in resolution only by the number of pulses that can be applied.

  19. AIRBORNE HIGH-RESOLUTION DIGITAL IMAGING SYSTEM

    Directory of Open Access Journals (Sweden)

    Prado-Molina, J.

    2006-04-01

    Full Text Available A low-cost airborne digital imaging system capable to perform aerial surveys with small-format cameras isintroduced. The equipment is intended to obtain high-resolution multispectral digital photographs constituting so aviable alternative to conventional aerial photography and satellite imagery. Monitoring software handles all theprocedures involved in image acquisition, including flight planning, real-time graphics for aircraft position updatingin a mobile map, and supervises the main variables engaged in the imaging process. This software also creates fileswith the geographical position of the central point of every image, and the flight path followed by the aircraftduring the entire survey. The cameras are mounted on a three-axis stabilized platform. A set of inertial sensorsdetermines platform's deviations independently from the aircraft and an automatic control system keeps thecameras at a continuous nadir pointing and heading, with a precision better than ± 1 arc-degree in three-axis. Thecontrol system is also in charge of saving the platform’s orientation angles when the monitoring software triggersthe camera. These external orientation parameters, together with a procedure for camera calibration give theessential elements for image orthocorrection. Orthomosaics are constructed using commercial GIS software.This system demonstrates the feasibility of large area coverage in a practical and economical way using smallformatcameras. Monitoring and automatization reduce the work while increasing the quality and the amount ofuseful images.

  20. Fundamental constants and high-resolution spectroscopy

    Science.gov (United States)

    Bonifacio, P.; Rahmani, H.; Whitmore, J. B.; Wendt, M.; Centurion, M.; Molaro, P.; Srianand, R.; Murphy, M. T.; Petitjean, P.; Agafonova, I. I.; D'Odorico, S.; Evans, T. M.; Levshakov, S. A.; Lopez, S.; Martins, C. J. A. P.; Reimers, D.; Vladilo, G.

    2014-01-01

    Absorption-line systems detected in high resolution quasar spectra can be used to compare the value of dimensionless fundamental constants such as the fine-structure constant, α, and the proton-to-electron mass ratio, μ = m_p/m_e, as measured in remote regions of the Universe to their value today on Earth. In recent years, some evidence has emerged of small temporal and also spatial variations in α on cosmological scales which may reach a fractional level of ≈ 10 ppm (parts per million). We are conducting a Large Programme of observations with the Very Large Telescope's Ultraviolet and Visual Echelle Spectrograph (UVES), and are obtaining high-resolution ({R ≈ 60 000}) and high signal-to-noise ratio (S/N ≈ 100) spectra calibrated specifically to study the variations of the fundamental constants. We here provide a general overview of the Large Programme and report on the first results for these two constants, discussed in detail in Molaro et al. (2013) and Rahmani et al. (2013). A stringent bound for Δα/α is obtained for the absorber at z_abs = 1.6919 towards HE 2217-2818. The absorption profile is complex with several very narrow features, and is modeled with 32 velocity components. The relative variation in α in this system is +1.3± 2.4_stat ± 1.0_sys ppm if Al II λ 1670 Å and three Fe II transitions are used, and +1.1 ± 2.6_stat ppm in a slightly different analysis with only Fe II transitions used. This is one of the tightest bounds on α-variation from an individual absorber and reveals no evidence for variation in α at the 3-ppm precision level (1σ confidence). The expectation at this sky position of the recently-reported dipolar variation of α is (3.2-5.4)±1.7 ppm depending on dipole model used and this constraint of Δα/α at face value is not supporting this expectation but not inconsistent with it at the 3σ level. For the proton-to-electron mass ratio the analysis of the H_2 absorption lines of the z_abs ≈ 2.4018 damped Lyα system

  1. High-resolution phylogenetic microbial community profiling

    Energy Technology Data Exchange (ETDEWEB)

    Singer, Esther; Coleman-Derr, Devin; Bowman, Brett; Schwientek, Patrick; Clum, Alicia; Copeland, Alex; Ciobanu, Doina; Cheng, Jan-Fang; Gies, Esther; Hallam, Steve; Tringe, Susannah; Woyke, Tanja

    2014-03-17

    The representation of bacterial and archaeal genome sequences is strongly biased towards cultivated organisms, which belong to merely four phylogenetic groups. Functional information and inter-phylum level relationships are still largely underexplored for candidate phyla, which are often referred to as microbial dark matter. Furthermore, a large portion of the 16S rRNA gene records in the GenBank database are labeled as environmental samples and unclassified, which is in part due to low read accuracy, potential chimeric sequences produced during PCR amplifications and the low resolution of short amplicons. In order to improve the phylogenetic classification of novel species and advance our knowledge of the ecosystem function of uncultivated microorganisms, high-throughput full length 16S rRNA gene sequencing methodologies with reduced biases are needed. We evaluated the performance of PacBio single-molecule real-time (SMRT) sequencing in high-resolution phylogenetic microbial community profiling. For this purpose, we compared PacBio and Illumina metagenomic shotgun and 16S rRNA gene sequencing of a mock community as well as of an environmental sample from Sakinaw Lake, British Columbia. Sakinaw Lake is known to contain a large age of microbial species from candidate phyla. Sequencing results show that community structure based on PacBio shotgun and 16S rRNA gene sequences is highly similar in both the mock and the environmental communities. Resolution power and community representation accuracy from SMRT sequencing data appeared to be independent of GC content of microbial genomes and was higher when compared to Illumina-based metagenome shotgun and 16S rRNA gene (iTag) sequences, e.g. full-length sequencing resolved all 23 OTUs in the mock community, while iTags did not resolve closely related species. SMRT sequencing hence offers various potential benefits when characterizing uncharted microbial communities.

  2. High resolution CT findings of pseudoalveolar sarcoidosis

    Energy Technology Data Exchange (ETDEWEB)

    Nam, Ji Eun; Park, Jun Gyun; Choe, Kyu Ok; Kim, Sang Jin [Yonsei University College of Medicine, Seoul (Korea, Republic of); Ryu, Young Hoon; Im, Jung Gi [Seoul National University College of Medicine, Seoul (Korea, Republic of); Lee, Kyoung Soo [Sungkunkwan University College of Medicine, Seoul (Korea, Republic of); Song, Koun Sik [University of Ulsan College of Medicine, Seoul (Korea, Republic of); Kim, Hyae Young [National Cancer Centar, Seoul (Korea, Republic of)

    2002-08-01

    To determine the specific high-resolution CT features of sarcoidosis in which the observed pattern is predominantly pseudoalveolar. We retrospectively reviewed the HRCT findings in 15 cases in which chest radiography demonstrated pseudoalveolar consolidation. In all 15, sarcoidosis was pathologically proven. The distribution and characterization of the following CT features was meticulously scrutinized: distribution and characterization of pseudoalveolar lesions, air-bronchograms, micronodules, thickening of bronchovascular bundles and interlobular septa, lung distortion, ground-glass opacities and combined hilar and mediastinal lymphadenopathy. Follow-up CT scans were available in three cases after corticosteroid administration. Between one and 12 (mean, 5.6) pseudoalveolar lesions appeared as dense homogeneous or inhomogeneous opacities 1-4.5 cm in diameter and with an irregular margin located either at the lung periphery adjacent to the pleural surface or along the bronchovascular bundles, with mainly bilateral distribution (n=14, 93%). An air-bronchogram was observed in ten cases. Micronodules were observed at the periphery of the lesion or surrounding lung, which along with a thickened bronchovascular bundle was a consistent feature in all cases. Additional CT features included hilar and mediastinal lymphadenopathy (n=14, 93%), thickened interlobular septa (n=12, 80%), and ground-glass opacity (n=10, 67%). Lung distortion was noted in only one case (7%). After steroid administration pseudoalveolar lesions decreased in number and size in all three cases in which follow-up CT was available. The consistent HRCT features of pseudoalveolar sarcoidosis are bilateral multifocal dense homogenous or inhomogenous opacity and an irregular margin located either at the lung periphery adjacent to the pleural surface or along the bronchovascular bundles. Micronodules are present at the periphery of the lesion or surrounding lung. The features are reversible administration.

  3. High-resolution downscaling for hydrological management

    Science.gov (United States)

    Ulbrich, Uwe; Rust, Henning; Meredith, Edmund; Kpogo-Nuwoklo, Komlan; Vagenas, Christos

    2017-04-01

    Hydrological modellers and water managers require high-resolution climate data to model regional hydrologies and how these may respond to future changes in the large-scale climate. The ability to successfully model such changes and, by extension, critical infrastructure planning is often impeded by a lack of suitable climate data. This typically takes the form of too-coarse data from climate models, which are not sufficiently detailed in either space or time to be able to support water management decisions and hydrological research. BINGO (Bringing INnovation in onGOing water management; ) aims to bridge the gap between the needs of hydrological modellers and planners, and the currently available range of climate data, with the overarching aim of providing adaptation strategies for climate change-related challenges. Producing the kilometre- and sub-daily-scale climate data needed by hydrologists through continuous simulations is generally computationally infeasible. To circumvent this hurdle, we adopt a two-pronged approach involving (1) selective dynamical downscaling and (2) conditional stochastic weather generators, with the former presented here. We take an event-based approach to downscaling in order to achieve the kilometre-scale input needed by hydrological modellers. Computational expenses are minimized by identifying extremal weather patterns for each BINGO research site in lower-resolution simulations and then only downscaling to the kilometre-scale (convection permitting) those events during which such patterns occur. Here we (1) outline the methodology behind the selection of the events, and (2) compare the modelled precipitation distribution and variability (preconditioned on the extremal weather patterns) with that found in observations.

  4. High Resolution Global View of Io

    Science.gov (United States)

    1997-01-01

    Io, the most volcanic body in the solar system is seen in the highest resolution obtained to date by NASA's Galileo spacecraft. The smallest features that can be discerned are 2.5 kilometers in size. There are rugged mountains several kilometers high, layered materials forming plateaus, and many irregular depressions called volcanic calderas. Several of the dark, flow-like features correspond to hot spots, and may be active lava flows. There are no landforms resembling impact craters, as the volcanism covers the surface with new deposits much more rapidly than the flux of comets and asteroids can create large impact craters. The picture is centered on the side of Io that always faces away from Jupiter; north is to the top.Color images acquired on September 7, 1996 have been merged with higher resolution images acquired on November 6, 1996 by the Solid State Imaging (CCD) system aboard NASA's Galileo spacecraft. The color is composed of data taken, at a range of 487,000 kilometers, in the near-infrared, green, and violet filters and has been enhanced to emphasize the extraordinary variations in color and brightness that characterize Io's face. The high resolution images were obtained at ranges which varied from 245,719 kilometers to 403,100 kilometers.Launched in October 1989, Galileo entered orbit around Jupiter on December 7, 1995. The spacecraft's mission is to conduct detailed studies of the giant planet, its largest moons and the Jovian magnetic environment. The Jet Propulsion Laboratory, Pasadena, CA manages the mission for NASA's Office of Space Science, Washington, DC.This image and other images and data received from Galileo are posted on the World Wide Web, on the Galileo mission home page at URL http://galileo.jpl.nasa.gov. Background information and educational context for the images can be found at URL http://www.jpl.nasa.gov/galileo/sepo

  5. High resolution ultraviolet imaging spectrometer for latent image analysis.

    Science.gov (United States)

    Lyu, Hang; Liao, Ningfang; Li, Hongsong; Wu, Wenmin

    2016-03-21

    In this work, we present a close-range ultraviolet imaging spectrometer with high spatial resolution, and reasonably high spectral resolution. As the transmissive optical components cause chromatic aberration in the ultraviolet (UV) spectral range, an all-reflective imaging scheme is introduced to promote the image quality. The proposed instrument consists of an oscillating mirror, a Cassegrain objective, a Michelson structure, an Offner relay, and a UV enhanced CCD. The finished spectrometer has a spatial resolution of 29.30μm on the target plane; the spectral scope covers both near and middle UV band; and can obtain approximately 100 wavelength samples over the range of 240~370nm. The control computer coordinates all the components of the instrument and enables capturing a series of images, which can be reconstructed into an interferogram datacube. The datacube can be converted into a spectrum datacube, which contains spectral information of each pixel with many wavelength samples. A spectral calibration is carried out by using a high pressure mercury discharge lamp. A test run demonstrated that this interferometric configuration can obtain high resolution spectrum datacube. The pattern recognition algorithm is introduced to analyze the datacube and distinguish the latent traces from the base materials. This design is particularly good at identifying the latent traces in the application field of forensic imaging.

  6. HIGH RESOLUTION AIRBORNE SHALLOW WATER MAPPING

    Directory of Open Access Journals (Sweden)

    F. Steinbacher

    2012-07-01

    Full Text Available In order to meet the requirements of the European Water Framework Directive (EU-WFD, authorities face the problem of repeatedly performing area-wide surveying of all kinds of inland waters. Especially for mid-sized or small rivers this is a considerable challenge imposing insurmountable logistical efforts and costs. It is therefore investigated if large-scale surveying of a river system on an operational basis is feasible by employing airborne hydrographic laser scanning. In cooperation with the Bavarian Water Authority (WWA Weilheim a pilot project was initiated by the Unit of Hydraulic Engineering at the University of Innsbruck and RIEGL Laser Measurement Systems exploiting the possibilities of a new LIDAR measurement system with high spatial resolution and high measurement rate to capture about 70 km of riverbed and foreland for the river Loisach in Bavaria/Germany and the estuary and parts of the shoreline (about 40km in length of lake Ammersee. The entire area surveyed was referenced to classic terrestrial cross-section surveys with the aim to derive products for the monitoring and managing needs of the inland water bodies forced by the EU-WFD. The survey was performed in July 2011 by helicopter and airplane and took 3 days in total. In addition, high resolution areal images were taken to provide an optical reference, offering a wide range of possibilities on further research, monitoring, and managing responsibilities. The operating altitude was about 500 m to maintain eye-safety, even for the aided eye, the airspeed was about 55 kts for the helicopter and 75 kts for the aircraft. The helicopter was used in the alpine regions while the fixed wing aircraft was used in the plains and the urban area, using appropriate scan rates to receive evenly distributed point clouds. The resulting point density ranged from 10 to 25 points per square meter. By carefully selecting days with optimum water quality, satisfactory penetration down to the river

  7. High Resolution Airborne Shallow Water Mapping

    Science.gov (United States)

    Steinbacher, F.; Pfennigbauer, M.; Aufleger, M.; Ullrich, A.

    2012-07-01

    In order to meet the requirements of the European Water Framework Directive (EU-WFD), authorities face the problem of repeatedly performing area-wide surveying of all kinds of inland waters. Especially for mid-sized or small rivers this is a considerable challenge imposing insurmountable logistical efforts and costs. It is therefore investigated if large-scale surveying of a river system on an operational basis is feasible by employing airborne hydrographic laser scanning. In cooperation with the Bavarian Water Authority (WWA Weilheim) a pilot project was initiated by the Unit of Hydraulic Engineering at the University of Innsbruck and RIEGL Laser Measurement Systems exploiting the possibilities of a new LIDAR measurement system with high spatial resolution and high measurement rate to capture about 70 km of riverbed and foreland for the river Loisach in Bavaria/Germany and the estuary and parts of the shoreline (about 40km in length) of lake Ammersee. The entire area surveyed was referenced to classic terrestrial cross-section surveys with the aim to derive products for the monitoring and managing needs of the inland water bodies forced by the EU-WFD. The survey was performed in July 2011 by helicopter and airplane and took 3 days in total. In addition, high resolution areal images were taken to provide an optical reference, offering a wide range of possibilities on further research, monitoring, and managing responsibilities. The operating altitude was about 500 m to maintain eye-safety, even for the aided eye, the airspeed was about 55 kts for the helicopter and 75 kts for the aircraft. The helicopter was used in the alpine regions while the fixed wing aircraft was used in the plains and the urban area, using appropriate scan rates to receive evenly distributed point clouds. The resulting point density ranged from 10 to 25 points per square meter. By carefully selecting days with optimum water quality, satisfactory penetration down to the river bed was achieved

  8. High resolution X-ray diffraction studies on unirradiated and ...

    Indian Academy of Sciences (India)

    High-resolution X-ray diffraction technique, employing a three-crystal monochromator–collimator ... observed by high-resolution electron microscopy in both ..... 1988 Nucl. Instrum. Meth. B34 228. Kato N 1992 J. Acta Crystallogr. A48 834. Kaur B, Bhat M, Licci F, Kumar R, Kotru P N and Bamzai K K. 2004 Nucl. Instrum. Meth ...

  9. Scalable Algorithms for Large High-Resolution Terrain Data

    DEFF Research Database (Denmark)

    Mølhave, Thomas; Agarwal, Pankaj K.; Arge, Lars Allan

    2010-01-01

    In this paper we demonstrate that the technology required to perform typical GIS computations on very large high-resolution terrain models has matured enough to be ready for use by practitioners. We also demonstrate the impact that high-resolution data has on common problems. To our knowledge, so...

  10. Achieving sensitive, high-resolution laser spectroscopy at CRIS

    Energy Technology Data Exchange (ETDEWEB)

    Groote, R. P. de [Instituut voor Kern- en Stralingsfysica, KU Leuven (Belgium); Lynch, K. M., E-mail: kara.marie.lynch@cern.ch [EP Department, CERN, ISOLDE (Switzerland); Wilkins, S. G. [The University of Manchester, School of Physics and Astronomy (United Kingdom); Collaboration: the CRIS collaboration

    2017-11-15

    The Collinear Resonance Ionization Spectroscopy (CRIS) experiment, located at the ISOLDE facility, has recently performed high-resolution laser spectroscopy, with linewidths down to 20 MHz. In this article, we present the modifications to the beam line and the newly-installed laser systems that have made sensitive, high-resolution measurements possible. Highlights of recent experimental campaigns are presented.

  11. High-resolution X-ray diffraction studies of multilayers

    DEFF Research Database (Denmark)

    Christensen, Finn Erland; Hornstrup, Allan; Schnopper, H. W.

    1988-01-01

    High-resolution X-ray diffraction studies of the perfection of state-of-the-art multilayers are presented. Data were obtained using a triple-axis perfect-crystal X-ray diffractometer. Measurements reveal large-scale figure errors in the substrate. A high-resolution triple-axis set up is required...

  12. High resolution UV spectroscopy and laser-focused nanofabrication

    NARCIS (Netherlands)

    Myszkiewicz, G.

    2005-01-01

    This thesis combines two at first glance different techniques: High Resolution Laser Induced Fluorescence Spectroscopy (LIF) of small aromatic molecules and Laser Focusing of atoms for Nanofabrication. The thesis starts with the introduction to the high resolution LIF technique of small aromatic

  13. Achieving sensitive, high-resolution laser spectroscopy at CRIS

    Science.gov (United States)

    de Groote, R. P.; Lynch, K. M.; Wilkins, S. G.

    2017-11-01

    The Collinear Resonance Ionization Spectroscopy (CRIS) experiment, located at the ISOLDE facility, has recently performed high-resolution laser spectroscopy, with linewidths down to 20 MHz. In this article, we present the modifications to the beam line and the newly-installed laser systems that have made sensitive, high-resolution measurements possible. Highlights of recent experimental campaigns are presented.

  14. On the Design of High Resolution Imaging Systems

    Science.gov (United States)

    Eckardt, A.; Reulke, R.

    2017-05-01

    The design of high-resolution systems is always a consideration of many parameters. Technological parameter of the imaging system, e.g. diameter of the imaging system, mass and power, as well as storage and data transfer, have an direct impact on spacecraft size and design. The paper describes the essential design parameters for the description of high-resolution systems.

  15. High-resolution 1 MS/s sub-2 radix split-capacitor SAR ADC

    Science.gov (United States)

    Cao, Chao; Zhu, Zhangming

    2017-10-01

    This paper proposes a high-resolution successive-approximation register (SAR) analog-to-digital converter (ADC) with sub-2 radix split-capacitor array architecture. The built-in redundancy of sub-2 radix architecture provides additional information in the digital calibration based on offset double injection. The calibration method is simple in structure and fast in convergence. The correction of errors in each bit is independent of those in the previous bit. A split-capacitor array is used to reduce the total capacitance especially in a high-resolution SAR ADC. An offset signal is injected by the switching scheme of capacitor array to minimize the hardware overhead. The prototype of 0.18 μm CMOS process obtains 14.46 bit ENOB and 95.65 dB SFDR after calibration. With calibration, the INL and DNL are ‑0.813/0.938 and ‑0.625/0.688, respectively.

  16. High Resolution Beam Orbit Measurement Electronics based on Compensated Diode Detectors

    CERN Document Server

    Gasior, M

    2010-01-01

    A high resolution beam position monitor (BPM) electronics based on diode peak detectors has been developed at CERN. The circuit processes the BPM electrode signals independently, converting the short beam pulses into slowly varying signals which can be digitized with high resolution ADCs operating in the kHz range or even measured with a DC voltmeter. For signals with peak amplitudes larger than some hundred mV the non-linear forward voltage of the diodes is compensated by a simple network using signals from two peak detectors, one with a single and the second with two diodes in series. This contribution presents results obtained with the first prototype in the laboratory and with the CERN-SPS beam. Ongoing development and possible future applications of the technique are also discussed.

  17. Linear Actuator Has Long Stroke and High Resolution

    Science.gov (United States)

    Cook, Brant T.; Moore, Donald M.; Braun, David F.; Koenig, John S.; Hankins, Steve M.

    2009-01-01

    The term precision linear actuator, direct drive ( PLADD ) refers to a robust linear actuator designed to be capable of repeatedly performing, over a lifetime of the order of 5 to 10 years, positioning maneuvers that include, variously, submicron increments or slews of the order of a centimeter. The PLADD is capable of both long stroke (120 mm) and high resolution (repeatable increments of 20 nm). Unlike precise linear actuators of prior design, the PLADD contains no gears, levers, or hydraulic converters. The PLADD, now at the prototype stage of development, is intended for original use as a coarse-positioning actuator in a spaceborne interferometer. The PLADD could also be adapted to terrestrial applications in which there are requirements for long stroke and high resolution: potential applications include medical imaging and fabrication of semiconductor devices. The PLADD (see figure) includes a commercially available ball-screw actuator driven directly by a commercially available three-phase brushless DC motor. The ball-screw actuator comprises a spring-preloaded ball nut on a ball screw that is restrained against rotation as described below. The motor is coupled directly (that is, without an intervening gear train) to a drive link that, in turn, is coupled to the ball nut. By eliminating the gear train, the direct-drive design eliminates the complexity, backlash, and potential for misalignment associated with a gear train. To prevent inadvertent movement, there is a brake that includes flexured levers compressed against the drive link by preload springs. This is a power-off brake: There are also piezoelectric stacks that can be activated to oppose the springs and push the levers away from the drive link. Hence, power must be applied to the piezoelectric stacks to release the drive link from braking. To help ensure long operational life, all of the mechanical drive components are immersed in an oil bath within hermetically sealed bellows. The outer end of the

  18. High Resolution, Range/Range-Rate Imager Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Visidyne proposes to develop a design for a small, lightweight, high resolution, in x, y, and z Doppler imager to assist in the guidance, navigation and control...

  19. Hurricane Satellite (HURSAT) from Advanced Very High Resolution Radiometer (AVHRR)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Huricane Satellite (HURSAT)-Advanced Very High Resolution Radiometer (AVHRR) is used to extend the HURSAT data set such that appling the Objective Dvorak technique...

  20. Methodology of high-resolution photography for mural condition database

    Science.gov (United States)

    Higuchi, R.; Suzuki, T.; Shibata, M.; Taniguchi, Y.

    2015-08-01

    Digital documentation is one of the most useful techniques to record the condition of cultural heritage. Recently, high-resolution images become increasingly useful because it is possible to show general views of mural paintings and also detailed mural conditions in a single image. As mural paintings are damaged by environmental stresses, it is necessary to record the details of painting condition on high-resolution base maps. Unfortunately, the cost of high-resolution photography and the difficulty of operating its instruments and software have commonly been an impediment for researchers and conservators. However, the recent development of graphic software makes its operation simpler and less expensive. In this paper, we suggest a new approach to make digital heritage inventories without special instruments, based on our recent our research project in Üzümlü church in Cappadocia, Turkey. This method enables us to achieve a high-resolution image database with low costs, short time, and limited human resources.

  1. A Forward-Looking High-Resolution GPR System

    National Research Council Canada - National Science Library

    Kositsky, Joel; Milanfar, Peyman

    1999-01-01

    A high-resolution ground penetrating radar (GPR) system was designed to help define the optimal radar parameters needed for the efficient standoff detection of buried and surface-laid antitank mines...

  2. High Resolution Orthoimagery = Orthorectified Metro Areas: 2000 - Present

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — High resolution orthorectified images combine the image characteristics of an aerial photograph with the geometric qualities of a map. An orthoimage is a...

  3. Topological Data Analysis of High-Resolution Temporal Rainfall

    Science.gov (United States)

    Carsteanu, Alin Andrei; Fernández Méndez, Félix; Vásquez Aguilar, Raciel

    2017-04-01

    This study applies topological data analysis (TDA) to the state space representations of high-resolution temporal rainfall intensity data from Iowa City (IIHR, U of Iowa). Using a sufficient embedding dimension, topological properties of the underlying manifold are depicted.

  4. NOAA High-Resolution Sea Surface Temperature (SST) Analysis Products

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This archive covers two high resolution sea surface temperature (SST) analysis products developed using an optimum interpolation (OI) technique. The analyses have a...

  5. Developing Visual Editors for High-Resolution Haptic Patterns

    DEFF Research Database (Denmark)

    Cuartielles, David; Göransson, Andreas; Olsson, Tony

    2012-01-01

    In this article we give an overview of our iterative work in developing visual editors for creating high resolution haptic patterns to be used in wearable, haptic feedback devices. During the past four years we have found the need to address the question of how to represent, construct and edit high...... resolution haptic patterns so that they translate naturally to the user’s haptic experience. To solve this question we have developed and tested several visual editors...

  6. High resolution x-ray and gamma ray imaging using diffraction lenses with mechanically bent crystals

    Science.gov (United States)

    Smither, Robert K [Hinsdale, IL

    2008-12-23

    A method for high spatial resolution imaging of a plurality of sources of x-ray and gamma-ray radiation is provided. High quality mechanically bent diffracting crystals of 0.1 mm radial width are used for focusing the radiation and directing the radiation to an array of detectors which is used for analyzing their addition to collect data as to the location of the source of radiation. A computer is used for converting the data to an image. The invention also provides for the use of a multi-component high resolution detector array and for narrow source and detector apertures.

  7. EMODnet High Resolution Seabed Mapping - further developing a high resolution digital bathymetry for European seas

    Science.gov (United States)

    Schaap, Dick M. A.; Schmitt, Thierry

    2017-04-01

    Access to marine data is a key issue for the EU Marine Strategy Framework Directive and the EU Marine Knowledge 2020 agenda and includes the European Marine Observation and Data Network (EMODnet) initiative. EMODnet aims at assembling European marine data, data products and metadata from diverse sources in a uniform way. The EMODnet data infrastructure is developed through a stepwise approach in three major phases. Currently EMODnet is entering its 3rd phase with operational portals providing access to marine data for bathymetry, geology, physics, chemistry, biology, seabed habitats and human activities, complemented by checkpoint projects, analysing the fitness for purpose of data provision. The EMODnet Bathymetry project has developed Digital Terrain Models (DTM) for the European seas. These have been produced from survey and aggregated data sets that are indexed with metadata by adopting the SeaDataNet Catalogue services. SeaDataNet is a network of major oceanographic data centres around the European seas that manage, operate and further develop a pan-European infrastructure for marine and ocean data management. The latest EMODnet Bathymetry DTM release has a resolution of 1/8 arcminute * 1/8 arcminute and covers all European sea regions. Use has been made of circa 7800 gathered survey datasets and composite DTMs from 27 European data providers from 15 countries. For areas without coverage use has been made of the latest GEBCO DTM. The catalogue services and the generated EMODnet DTM have been published at the dedicated EMODnet Bathymetry portal which includes a versatile DTM viewing service that also supports downloading in various formats. End December 2016 the Bathymetry project has been succeeded by EMODnet High Resolution Seabed Mapping (HRSM) as part of the third phase of EMODnet. This new project will continue gathering of bathymetric in-situ data sets with extra efforts for near coastal waters and coastal zones. In addition Satellite Derived Bathymetry

  8. Role of light satellites in the high-resolution Earth observation domain

    Science.gov (United States)

    Fishman, Moshe

    1999-12-01

    Current 'classic' applications using and exploring space based earth imagery are exclusive, narrow niche tailored, expensive and hardly accessible. On the other side new, inexpensive and widely used 'consumable' applications will be only developed concurrently to the availability of appropriate imagery allowing that process. A part of these applications can be imagined today, like WWW based 'virtual tourism' or news media, but the history of technological, cultural and entertainment evolution teaches us that most of future applications are unpredictable -- they emerge together with the platforms enabling their appearance. The only thing, which can be ultimately stated, is that the definitive condition for such applications is the availability of the proper imagery platform providing low cost, high resolution, large area, quick response, simple accessibility and quick dissemination of the raw picture. This platform is a constellation of Earth Observation satellites. Up to 1995 the Space Based High Resolution Earth Observation Domain was dominated by heavy, super-expensive and very inflexible birds. The launch of Israeli OFEQ-3 Satellite by MBT Division of Israel Aircraft Industries (IAI) marked the entrance to new era of light, smart and cheap Low Earth Orbited Imaging satellites. The Earth Resource Observation System (EROS) initiated by West Indian Space, is based on OFEQ class Satellites design and it is capable to gather visual data of Earth Surface both at high resolution and large image capacity. The main attributes, derived from its compact design, low weight and sophisticated logic and which convert the EROS Satellite to valuable and productive system, are discussed. The major advantages of Light Satellites in High Resolution Earth Observation Domain are presented and WIS guidelines featuring the next generation of LEO Imaging Systems are included.

  9. A high-resolution vehicle emission inventory for China

    Science.gov (United States)

    Zheng, B.; Zhang, Q.; He, K.; Huo, H.; Yao, Z.; Wang, X.

    2012-12-01

    Developing high resolution emission inventory is an essential task for air quality modeling and management. However, current vehicle emission inventories in China are usually developed at provincial level and then allocated to grids based on various spatial surrogates, which is difficult to get high spatial resolution. In this work, we developed a new approach to construct a high-resolution vehicle emission inventory for China. First, vehicle population at county level were estimated by using the relationship between per-capita GDP and vehicle ownership. Then the Weather Research and Forecasting (WRF) model were used to drive the International Vehicle Emission (IVE) model to get monthly emission factors for each county. Finally, vehicle emissions by county were allocated to grids with 5-km horizon resolution by using high-resolution road network data. This work provides a better understanding of spatial representation of vehicle emissions in China and can benefit both air quality modeling and management with improved spatial accuracy.

  10. Single sensor processing to obtain high resolution color component signals

    Science.gov (United States)

    Glenn, William E. (Inventor)

    2010-01-01

    A method for generating color video signals representative of color images of a scene includes the following steps: focusing light from the scene on an electronic image sensor via a filter having a tri-color filter pattern; producing, from outputs of the sensor, first and second relatively low resolution luminance signals; producing, from outputs of the sensor, a relatively high resolution luminance signal; producing, from a ratio of the relatively high resolution luminance signal to the first relatively low resolution luminance signal, a high band luminance component signal; producing, from outputs of the sensor, relatively low resolution color component signals; and combining each of the relatively low resolution color component signals with the high band luminance component signal to obtain relatively high resolution color component signals.

  11. Compact and high-resolution optical orbital angular momentum sorter

    Directory of Open Access Journals (Sweden)

    Chenhao Wan

    2017-03-01

    Full Text Available A compact and high-resolution optical orbital angular momentum (OAM sorter is proposed and demonstrated. The sorter comprises a quadratic fan-out mapper and a dual-phase corrector positioned in the pupil plane and the Fourier plane, respectively. The optical system is greatly simplified compared to previous demonstrations of OAM sorting, and the performance in resolution and efficiency is maintained. A folded configuration is set up using a single reflective spatial light modulator (SLM to demonstrate the validity of the scheme. The two phase elements are implemented on the left and right halves of the SLM and connected by a right-angle prism. Experimental results demonstrate the high resolution of the compact OAM sorter, and the current limit in efficiency can be overcome by replacing with transmissive SLMs and removing the beam splitters. This novel scheme paves the way for the miniaturization and integration of high-resolution OAM sorters.

  12. High-resolution interference with programmable classical incoherent light.

    Science.gov (United States)

    Zhang, Er-Feng; Liu, Wei-Tao; Chen, Ping-Xing

    2015-07-01

    A scheme of high-resolution interference with classical incoherent light is proposed. In this scheme, the classical incoherent light is programmable in the amplitude distribution and wavefront, and with the programmable classical incoherent light we improve the resolution of the interference pattern by a factor of 2 compared with the scheme by Erkmen [J. Opt. Soc. Am. A29, 782 (2012)JOAOD60740-323210.1364/JOSAA.29.000782]. Compared with other schemes for observing interference patterns, only single-pixel detection is needed in our proposal. Moreover, the high-resolution interference pattern can be inverted to obtain an image with better resolution compared with that of the scheme proposed by Erkmen. Furthermore, this scheme of high-resolution interference is verified in detail by theoretical analysis and numerical simulations.

  13. Integrated High Resolution Digital Color Light Sensor in 130 nm CMOS Technology.

    Science.gov (United States)

    Strle, Drago; Nahtigal, Uroš; Batistell, Graciele; Zhang, Vincent Chi; Ofner, Erwin; Fant, Andrea; Sturm, Johannes

    2015-07-22

    This article presents a color light detection system integrated in 130 nm CMOS technology. The sensors and corresponding electronics detect light in a CIE XYZ color luminosity space using on-chip integrated sensors without any additional process steps, high-resolution analog-to-digital converter, and dedicated DSP algorithm. The sensor consists of a set of laterally arranged integrated photodiodes that are partly covered by metal, where color separation between the photodiodes is achieved by lateral carrier diffusion together with wavelength-dependent absorption. A high resolution, hybrid, ∑∆ ADC converts each photo diode's current into a 22-bit digital result, canceling the dark current of the photo diodes. The digital results are further processed by the DSP, which calculates normalized XYZ or RGB color and intensity parameters using linear transformations of the three photo diode responses by multiplication of the data with a transformation matrix, where the coefficients are extracted by training in combination with a pseudo-inverse operation and the least-mean square approximation. The sensor system detects the color light parameters with 22-bit accuracy, consumes less than 60 μA on average at 10 readings per second, and occupies approx. 0.8 mm(2) of silicon area (including three photodiodes and the analog part of the ADC). The DSP is currently implemented on FPGA.

  14. Integrated High Resolution Digital Color Light Sensor in 130 nm CMOS Technology

    Directory of Open Access Journals (Sweden)

    Drago Strle

    2015-07-01

    Full Text Available This article presents a color light detection system integrated in 130 nm CMOS technology. The sensors and corresponding electronics detect light in a CIE XYZ color luminosity space using on-chip integrated sensors without any additional process steps, high-resolution analog-to-digital converter, and dedicated DSP algorithm. The sensor consists of a set of laterally arranged integrated photodiodes that are partly covered by metal, where color separation between the photodiodes is achieved by lateral carrier diffusion together with wavelength-dependent absorption. A high resolution, hybrid, ∑∆ ADC converts each photo diode’s current into a 22-bit digital result, canceling the dark current of the photo diodes. The digital results are further processed by the DSP, which calculates normalized XYZ or RGB color and intensity parameters using linear transformations of the three photo diode responses by multiplication of the data with a transformation matrix, where the coefficients are extracted by training in combination with a pseudo-inverse operation and the least-mean square approximation. The sensor system detects the color light parameters with 22-bit accuracy, consumes less than 60 μA on average at 10 readings per second, and occupies approx. 0.8 mm2 of silicon area (including three photodiodes and the analog part of the ADC. The DSP is currently implemented on FPGA.

  15. O-space with high resolution readouts outperforms radial imaging.

    Science.gov (United States)

    Wang, Haifeng; Tam, Leo; Kopanoglu, Emre; Peters, Dana C; Constable, R Todd; Galiana, Gigi

    2017-04-01

    While O-Space imaging is well known to accelerate image acquisition beyond traditional Cartesian sampling, its advantages compared to undersampled radial imaging, the linear trajectory most akin to O-Space imaging, have not been detailed. In addition, previous studies have focused on ultrafast imaging with very high acceleration factors and relatively low resolution. The purpose of this work is to directly compare O-Space and radial imaging in their potential to deliver highly undersampled images of high resolution and minimal artifacts, as needed for diagnostic applications. We report that the greatest advantages to O-Space imaging are observed with extended data acquisition readouts. A sampling strategy that uses high resolution readouts is presented and applied to compare the potential of radial and O-Space sequences to generate high resolution images at high undersampling factors. Simulations and phantom studies were performed to investigate whether use of extended readout windows in O-Space imaging would increase k-space sampling and improve image quality, compared to radial imaging. Experimental O-Space images acquired with high resolution readouts show fewer artifacts and greater sharpness than radial imaging with equivalent scan parameters. Radial images taken with longer readouts show stronger undersampling artifacts, which can cause small or subtle image features to disappear. These features are preserved in a comparable O-Space image. High resolution O-Space imaging yields highly undersampled images of high resolution and minimal artifacts. The additional nonlinear gradient field improves image quality beyond conventional radial imaging. Copyright © 2016 Elsevier Inc. All rights reserved.

  16. High-resolution low-dose scanning transmission electron microscopy.

    Science.gov (United States)

    Buban, James P; Ramasse, Quentin; Gipson, Bryant; Browning, Nigel D; Stahlberg, Henning

    2010-01-01

    During the past two decades instrumentation in scanning transmission electron microscopy (STEM) has pushed toward higher intensity electron probes to increase the signal-to-noise ratio of recorded images. While this is suitable for robust specimens, biological specimens require a much reduced electron dose for high-resolution imaging. We describe here protocols for low-dose STEM image recording with a conventional field-emission gun STEM, while maintaining the high-resolution capability of the instrument. Our findings show that a combination of reduced pixel dwell time and reduced gun current can achieve radiation doses comparable to low-dose TEM.

  17. Theoretical Problems in High Resolution Solar Physics, 2

    Science.gov (United States)

    Athay, G. (Editor); Spicer, D. S. (Editor)

    1987-01-01

    The Science Working Group for the High Resolution Solar Observatory (HRSO) laid plans beginning in 1984 for a series of workshops designed to stimulate a broadbased input from the scientific community to the HRSO mission. These workshops have the dual objectives of encouraging an early start on the difficult theoretical problems in radiative transfer, magnetohydrodynamics, and plasma physics that will be posed by the HRSO data, and maintaining current discussions of results in high resolution solar studies. This workshop was the second in the series. The workshop format presented invited review papers during the formal sessions and contributed poster papers for discussions during open periods. Both are presented.

  18. Inferring sediment connectivity from high-resolution DEMs of Difference

    Science.gov (United States)

    Heckmann, Tobias; Vericat, Damià

    2017-04-01

    Topographic changes due to the erosion and deposition of bedrock, sediments and soil can be measured by differencing Digital Elevation Models (DEM) acquired at different points in time. So-called morphological sediment budgets can be computed from such DEMs of Difference (DoD) on an areal rather than a point basis. The advent of high-resolution and highly accurate surveying techniques (e.g. LiDAR, SfM), together with recent advances of survey platforms (e.g. UaVs) provides opportunities to improve the spatial and temporal scale (in terms of extent and resolution), the availability and quality of such measurements. Many studies have used DoD to investigate and interpret the spatial pattern of positive and negative vertical differences in terms of erosion and deposition, or of horizontal movement. Vertical differences can be converted to volumes, and negative (erosion) and positive (deposition) volumetric changes aggregated for spatial units (e.g., landforms, hillslopes, river channels) have been used to compute net balances. We argue that flow routing algorithms common in digital terrain analysis provide a means to enrich DoD-based investigations with some information about (potential) sediment pathways - something that has been widely neglected in previous studies. Where the DoD indicates a positive surface change, flow routing delineates the upslope area where the deposited sediment has potentially been derived from. In the downslope direction, flow routing indicates probable downslope pathways of material eroded/detached/entrained where the DoD shows negative surface change. This material has either been deposited along these pathways or been flushed out of the area of investigation. This is a question of sediment connectivity, a property of a system (i.e. a hillslope, a sub-/catchment) that describes its potential to move sediment through itself. The sediment pathways derived from the DEM are related to structural connectivity, while the spatial pattern of (net

  19. Remote parallel rendering for high-resolution tiled display walls

    KAUST Repository

    Nachbaur, Daniel

    2014-11-01

    © 2014 IEEE. We present a complete, robust and simple to use hardware and software stack delivering remote parallel rendering of complex geometrical and volumetric models to high resolution tiled display walls in a production environment. We describe the setup and configuration, present preliminary benchmarks showing interactive framerates, and describe our contributions for a seamless integration of all the software components.

  20. Input variable selection for interpolating high-resolution climate ...

    African Journals Online (AJOL)

    2010-10-20

    Oct 20, 2010 ... Accurate climate surfaces are vital for applications relating to groundwater recharge modelling, evapotranspiration estima- ... with distance to oceans and elevation to generate 8 sets of high-resolution (i.e. 3 arc second) climate surfaces of the Western .... ANUSPLIN, developed by the Australian National.

  1. High resolution numerical weather prediction over the Indian ...

    Indian Academy of Sciences (India)

    In this study, the Florida State University Global Spectral Model (FSUGSM), in association with a high-resolution nested regional spectral model (FSUNRSM), is used for short-range weather forecasts over the Indian domain. Three-day forecasts for each day of August 1998 were performed using different versions of the ...

  2. Track prediction of very severe cyclone 'Nargis' using high resolution ...

    Indian Academy of Sciences (India)

    In the present study, a detailed diagnostic analysis of the system 'Nargis' is carried out initially to investigate the features associated with this unusual movement and subsequently the real time forecast of VSCS 'Nargis' using high resolution advanced version weather research forecasting (WRF) model is presented.

  3. HIGH RESOLUTION RESISTIVITY LEAK DETECTION DATA PROCESSING & EVALUATION MEHTODS & REQUIREMENTS

    Energy Technology Data Exchange (ETDEWEB)

    SCHOFIELD JS

    2007-10-04

    This document has two purposes: {sm_bullet} Describe how data generated by High Resolution REsistivity (HRR) leak detection (LD) systems deployed during single-shell tank (SST) waste retrieval operations are processed and evaluated. {sm_bullet} Provide the basic review requirements for HRR data when Hrr is deployed as a leak detection method during SST waste retrievals.

  4. Workshop on high-resolution, large-acceptance spectrometers

    Energy Technology Data Exchange (ETDEWEB)

    Zeidman, B. (ed.)

    1981-01-01

    The purpose of the Workshop on High-Resolution, Large-Acceptance Spectrometers was to provide a means for exchange of information among those actively engaged in the design and construction of these new spectrometers. Thirty-seven papers were prepared for the data base.

  5. High-resolution seismic imaging of the Sohagpur Gondwana basin ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Earth System Science; Volume 122; Issue 6 ... In this study, we illustrate how Gondwana tectonics affected the Sohagpur Gondwana basin that occurs at the junction of the Mahanadi and Son–Narmada rift systems in the central India, through a high-resolution seismic reflection study along six ...

  6. Bombs at High Resolution. I. Morphological Evidence for Photospheric Reconnection

    NARCIS (Netherlands)

    Watanabe, H.; Vissers, G.; Kitai, R.; Rouppe van der Voort, L.H.M.; Rutten, R.J.|info:eu-repo/dai/nl/074143662

    2011-01-01

    High-resolution imaging-spectroscopy movies of solar active region NOAA 10998 obtained with the Crisp Imaging Spectropolarimeter at the Swedish 1-m Solar Telescope show very bright, rapidly flickering, flame-like features that appear intermittently in the wings of the Balmer Hα line in a region with

  7. Calibration of a High Resolution Airborne 3-D SAR

    DEFF Research Database (Denmark)

    Dall, Jørgen; Grinder-Pedersen, Jan; Madsen, S.N.

    1997-01-01

    The potential of across-track interferometric (XTI) synthetic aperture radar (SAR) for producing high resolution 3D imagery has been demonstrated by several airborne systems including EMISAR, the dual frequency, polarimetric, and interferometric SAR developed at the Dept. of Electromagnetic Systems...

  8. Comparison of High Resolution Negative Electron Beam Resists

    DEFF Research Database (Denmark)

    Olsen, Brian Bilenberg; Schøler, Mikkel; Shi, Peixiong

    2006-01-01

    Four high resolution negative electron beam resists are compared: TEBN-1 from Tokuyama Corp. Japan, ma-N 2401XP and mr-L 6000AXP from microresist technology GmbH Germany, and SU-8 2000 series from MicroChem Corp., USA. Narrow linewidth high density patterns are defined by 100 kV electron beam...

  9. High-resolution spectroscopy of gases for industrial applications

    DEFF Research Database (Denmark)

    Fateev, Alexander; Clausen, Sønnik

    for analysis of complex experimental data and further development of the databases. High-temperature gas cell facilities available at DTU Chemical Engineering are presented and described. The gas cells and high-resolution spectrometers allow us to perform high-quality reference measurements of gases relevant...

  10. High Resolution Digital Imaging of Paintings: The Vasari Project.

    Science.gov (United States)

    Martinez, Kirk

    1991-01-01

    Describes VASARI (the Visual Art System for Archiving and Retrieval of Images), a project funded by the European Community to show the feasibility of high resolution colormetric imaging directly from paintings. The hardware and software used in the system are explained, storage on optical disks is described, and initial results are reported. (five…

  11. Amplification of real-time high resolution melting analysis PCR ...

    African Journals Online (AJOL)

    In this study, we assessed the usefulness of eight common primers amplifying the respective genes in real-time high resolution melting analysis PCR (real-time HRMA PCR) in terms of time, cost and sensitivity with respect to PCR-SSCP method. We found that case sample can easily be differentiated from control sample by ...

  12. High resolution spectroscopy of the disk chromosphere. I - Observing procedures.

    Science.gov (United States)

    Beckers, J. M.; Mauter, H. A.; Mann, G. R.; Brown, D. R.

    1972-01-01

    Review of some of the main features of a high resolution spectroscopy program aimed at the precise photometric observation of chromospheric fine structures using the Sacramento Peak vacuum telescope. The observing procedures are described, and a sample of the first observational results is presented.

  13. High-Resolution Stamp Fabrication by Edge Lithography

    NARCIS (Netherlands)

    Zhao, Yiping

    2010-01-01

    The aim of the project was to create high resolution stamps for thermal nanoimprint applications. The creation of nanoridges with sub-100 nm resolutions was explored by means of edge lithography via top-down routes, i.e. in combination with micromachining technology. Edge lithography is an add-on

  14. High resolution STEM of quantum dots and quantum wires

    DEFF Research Database (Denmark)

    Kadkhodazadeh, Shima

    2013-01-01

    This article reviews the application of high resolution scanning transmission electron microscopy (STEM) to semiconductor quantum dots (QDs) and quantum wires (QWRs). Different imaging and analytical techniques in STEM are introduced and key examples of their application to QDs and QWRs...

  15. High resolution EPR applications to metalloenzymes and metals in medicine

    CERN Document Server

    Berliner, Lawrence

    2009-01-01

    EPR spectroscopy has an important role in the geometric structural characterization of the redox cofactors in metalloproteins and their electronic structure, as this is crucial for their reactivity. This title covers high-resolution EPR methods, iron proteins, nickel and copper enzymes, and metals in medicine.

  16. A high resolution powder diffractometer using focusing optics

    Indian Academy of Sciences (India)

    Research Centre, Mumbai 400 085, India. *Corresponding author. E-mail: siruguri@csr.ernet.in. Abstract. In this paper, we describe the design, construction and performance of a new high resolution neutron powder diffractometer that has been installed at the Dhruva reactor, Trombay, India. The instrument employs novel ...

  17. High resolution reflection seismic mapping of shallow coal seams

    CSIR Research Space (South Africa)

    Mngadi, SB

    2013-10-01

    Full Text Available Subsidence and collapse of unmapped shallow coal mine workings poses a risk to the public and hampers the development of valuable property. A high-resolution reflection seismic survey was conducted to determine whether it is possible to map...

  18. High resolution X-ray diffraction studies on unirradiated and ...

    Indian Academy of Sciences (India)

    High-resolution X-ray diffraction technique, employing a three-crystal monochromator–collimator combination is used to study the irradiation induced defects in flux grown Sr-hexaferrite crystals irradiated with 50 MeV Li3+ ion beams at room temperature with a fluence value of 1 × 1014 ions/cm2. The diffraction curves of the ...

  19. High resolution mid-infrared spectroscopy based on frequency upconversion

    DEFF Research Database (Denmark)

    Dam, Jeppe Seidelin; Hu, Qi; Tidemand-Lichtenberg, Peter

    2013-01-01

    We present high resolution upconversion of incoherent infrared radiation by means of sum-frequency mixing with a laser followed by simple CCD Si-camera detection. Noise associated with upconversion is, in strong contrast to room temperature direct mid-IR detection, extremely small, thus very faint...

  20. Interpretation of high resolution aeromagnetic data over southern ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Earth System Science; Volume 125; Issue 2 ... High resolution airborne magnetic data of parts of the southern Benue Trough were digitally processed and analyzed in order to estimate the depth of magnetic sources and to map the distribution and orientation of subsurface structural features.

  1. Application of high-resolution melting for variant scanning in ...

    African Journals Online (AJOL)

    High-resolution melting (HRM) analysis is a rapid and sensitive method for single nucleotide polymorphism (SNP) analysis. In this study, a novel HRM assay was carried out to detect SNPs in the chloroplast gene atpB which encodes the beta subunit of the ATP synthase and atpB upstream intergenic region.

  2. High resolution resist-free lithography in the SEM

    NARCIS (Netherlands)

    Hari, S.

    2017-01-01

    Focussed Electron Beam Induced Processing is a high resolution direct-write nanopatterning technique. Its ability to fabricate sub-10 nm structures together with its versatility and ease of use, in that it is resist-free and implementable inside a Scanning Electron Microscope, make it attractive for

  3. Systematic high-resolution assessment of global hydropower potential

    NARCIS (Netherlands)

    Hoes, Olivier A C; Meijer, Lourens J J; Van Der Ent, Ruud J.; Van De Giesen, Nick C.

    2017-01-01

    Population growth, increasing energy demand and the depletion of fossil fuel reserves necessitate a search for sustainable alternatives for electricity generation. Hydropower could replace a large part of the contribution of gas and oil to the present energy mix. However, previous high-resolution

  4. Dual camera system for acquisition of high resolution images

    Science.gov (United States)

    Papon, Jeremie A.; Broussard, Randy P.; Ives, Robert W.

    2007-02-01

    Video surveillance is ubiquitous in modern society, but surveillance cameras are severely limited in utility by their low resolution. With this in mind, we have developed a system that can autonomously take high resolution still frame images of moving objects. In order to do this, we combine a low resolution video camera and a high resolution still frame camera mounted on a pan/tilt mount. In order to determine what should be photographed (objects of interest), we employ a hierarchical method which first separates foreground from background using a temporal-based median filtering technique. We then use a feed-forward neural network classifier on the foreground regions to determine whether the regions contain the objects of interest. This is done over several frames, and a motion vector is deduced for the object. The pan/tilt mount then focuses the high resolution camera on the next predicted location of the object, and an image is acquired. All components are controlled through a single MATLAB graphical user interface (GUI). The final system we present will be able to detect multiple moving objects simultaneously, track them, and acquire high resolution images of them. Results will demonstrate performance tracking and imaging varying numbers of objects moving at different speeds.

  5. pattern of interstitial lung disease as seen by high resolution

    African Journals Online (AJOL)

    2012-09-01

    Sep 1, 2012 ... Background: Diffuse lung diseases constitute a major cause of morbidity and mortality worldwide. High Resolution Computed Tomography (HRCT) is the recommended imaging technique in the diagnosis, assessment and followup of these diseases. Objectives: To describe the pattern of HRCT findings in ...

  6. FMC cameras, high resolution films and very large scale mapping

    Science.gov (United States)

    Tachibana, Kikuo; Hasegawa, Hiroyuki

    1988-06-01

    Very large scale mapping (1/250) was experimented on the basis of FMC camera, high resolution film and total station surveying. The future attractive combination of precision photogrammetry and personal computer assisted terrestrial surveying was investigated from the point of view of accuracy, time effectiveness and total procedures control.

  7. Signal Processing for High Resolution FMCW SAR and Moving Target

    NARCIS (Netherlands)

    Meta, A.; Hoogeboom, P.

    2005-01-01

    The combination of Frequency Modulated ContinuousWave (FMCW) technology and Synthetic Aperture Radar (SAR) leads to lightweight, cost-effective imaging sensors of high resolution. In FMCW SAR applications the conventional stop-and-go approximation used in pulse radar algorithms cannot be considered

  8. Impact of high resolution land surface initialization in Indian summer ...

    Indian Academy of Sciences (India)

    The direct impact of high resolution land surface initialization on the forecast bias in a regional climatemodel in recent years over Indian summer monsoon region is investigated. Two sets of regional climatemodel simulations are performed, one with a coarse resolution land surface initial conditions and secondone used a ...

  9. Plant respirometer enables high resolution of oxygen consumption rates

    Science.gov (United States)

    Foster, D. L.

    1966-01-01

    Plant respirometer permits high resolution of relatively small changes in the rate of oxygen consumed by plant organisms undergoing oxidative metabolism in a nonphotosynthetic state. The two stage supply and monitoring system operates by a differential pressure transducer and provides a calibrated output by digital or analog signals.

  10. Towards high resolution data assimilation and ensemble forecasting

    NARCIS (Netherlands)

    Stappers, R.J.J.

    2013-01-01

    Due the increase in computational power of supercomputers the grid resolution of high resolution numerical weather prediction models is now reaching the 1 km scale. As a result, mesoscale processes related to high impact weather (such as deep convection) can now explicitly be resolved by the models.

  11. Reproducible high-resolution multispectral image acquisition in dermatology

    Science.gov (United States)

    Duliu, Alexandru; Gardiazabal, José; Lasser, Tobias; Navab, Nassir

    2015-07-01

    Multispectral image acquisitions are increasingly popular in dermatology, due to their improved spectral resolution which enables better tissue discrimination. Most applications however focus on restricted regions of interest, imaging only small lesions. In this work we present and discuss an imaging framework for high-resolution multispectral imaging on large regions of interest.

  12. High-resolution axial MR imaging of tibial stress injuries

    Science.gov (United States)

    2012-01-01

    Purpose To evaluate the relative involvement of tibial stress injuries using high-resolution axial MR imaging and the correlation with MR and radiographic images. Methods A total of 33 patients with exercise-induced tibial pain were evaluated. All patients underwent radiograph and high-resolution axial MR imaging. Radiographs were taken at initial presentation and 4 weeks later. High-resolution MR axial images were obtained using a microscopy surface coil with 60 × 60 mm field of view on a 1.5T MR unit. All images were evaluated for abnormal signals of the periosteum, cortex and bone marrow. Results Nineteen patients showed no periosteal reaction at initial and follow-up radiographs. MR imaging showed abnormal signals in the periosteal tissue and partially abnormal signals in the bone marrow. In 7 patients, periosteal reaction was not seen at initial radiograph, but was detected at follow-up radiograph. MR imaging showed abnormal signals in the periosteal tissue and entire bone marrow. Abnormal signals in the cortex were found in 6 patients. The remaining 7 showed periosteal reactions at initial radiograph. MR imaging showed abnormal signals in the periosteal tissue in 6 patients. Abnormal signals were seen in the partial and entire bone marrow in 4 and 3 patients, respectively. Conclusions Bone marrow abnormalities in high-resolution axial MR imaging were related to periosteal reactions at follow-up radiograph. Bone marrow abnormalities might predict later periosteal reactions, suggesting shin splints or stress fractures. High-resolution axial MR imaging is useful in early discrimination of tibial stress injuries. PMID:22574840

  13. Catalytic converter

    Energy Technology Data Exchange (ETDEWEB)

    Liber, B.

    1991-08-22

    A catalytic converter is provided which is economical to manufacture and is not readily poisoned by contaminants in a gas stream such as would be encountered in the operation of an internal combustion engine, whereby an improved life expectancy of the unit can be achieved. The converter of the invention comprises a sintered porous body including molybdenum or a molybdenum-containing compound or a molybdenum complex. A method of forming a catlytic converter unit comprises forming a slurry including molybdenum or a molybdenum compound, forming the slurry into a sintered body member, and hardening or curing the same to form a self-sustaining body member. A method for treating an exhaust gas using the above catalytic converter is also disclosed. A preferred embodiment for an internal combustion engine is described. Examples of different catalytic compositions are included. 13 figs.

  14. High resolution reservoir geological modelling using outcrop information

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Changmin; Lin Kexiang; Liu Huaibo [Jianghan Petroleum Institute, Hubei (China)] [and others

    1997-08-01

    This is China`s first case study of high resolution reservoir geological modelling using outcrop information. The key of the modelling process is to build a prototype model and using the model as a geological knowledge bank. Outcrop information used in geological modelling including seven aspects: (1) Determining the reservoir framework pattern by sedimentary depositional system and facies analysis; (2) Horizontal correlation based on the lower and higher stand duration of the paleo-lake level; (3) Determining the model`s direction based on the paleocurrent statistics; (4) Estimating the sandbody communication by photomosaic and profiles; (6) Estimating reservoir properties distribution within sandbody by lithofacies analysis; and (7) Building the reservoir model in sandbody scale by architectural element analysis and 3-D sampling. A high resolution reservoir geological model of Youshashan oil field has been built by using this method.

  15. Fabricating High-Resolution X-Ray Collimators

    Science.gov (United States)

    Appleby, Michael; Atkinson, James E.; Fraser, Iain; Klinger, Jill

    2008-01-01

    A process and method for fabricating multi-grid, high-resolution rotating modulation collimators for arcsecond and sub-arcsecond x-ray and gamma-ray imaging involves photochemical machining and precision stack lamination. The special fixturing and etching techniques that have been developed are used for the fabrication of multiple high-resolution grids on a single array substrate. This technology has application in solar and astrophysics and in a number of medical imaging applications including mammography, computed tomography (CT), single photon emission computed tomography (SPECT), and gamma cameras used in nuclear medicine. This collimator improvement can also be used in non-destructive testing, hydrodynamic weapons testing, and microbeam radiation therapy.

  16. The theory and practice of high resolution scanning electron microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Joy, D.C. (Tennessee Univ., Knoxville, TN (USA) Oak Ridge National Lab., TN (USA))

    1990-01-01

    Recent advances in instrumentation have produced the first commercial examples of what can justifiably be called High Resolution Scanning Electron Microscopes. The key components of such instruments are a cold field emission gun, a small-gap immersion probe-forming lens, and a clean dry-pumped vacuum. The performance of these microscopes is characterized by several major features including a spatial resolution, in secondary electron mode on solid specimens, which can exceed 1nm on a routine basis; an incident probe current density of the order of 10{sup 6} amps/cm{sup 2}; and the ability to maintain these levels of performance over an accelerating voltage range of from 1 to 30keV. This combination of high resolution, high probe current, low contamination and flexible electron-optical conditions provides many new opportunitites for the application of the SEM to materials science, physics, and the life sciences. 27 refs., 14 figs.

  17. Automatic Matching of High Resolution Satellite Images Based on RFM

    Directory of Open Access Journals (Sweden)

    JI Shunping

    2016-02-01

    Full Text Available A matching method for high resolution satellite images based on RFM is presented.Firstly,the RFM parameters are used to predict the initial parallax of corresponding points and the prediction accuracy is analyzed.Secondly,the approximate epipolar equation is constructed based on projection tracking and its accuracy is analyzed.Thirdly,approximate 1D image matching is executed on pyramid images and least square matching on base images.At last RANSAC is imbedded to eliminate mis-matching points and matching results are obtained.Test results verified the method more robust and with higher matching rate,compared to 2D gray correlation method and the popular SIFT matching method,and the method preferably solved the question of high resolution satellite image matching with different stereo model,different time and large rotation images.

  18. High-Resolution Fluorescence Microscope Imaging of Erythroblast Structure.

    Science.gov (United States)

    Smith, Alyson S; Nowak, Roberta B; Fowler, Velia M

    2018-01-01

    During erythropoiesis, erythroblasts undergo dramatic morphological changes to produce mature erythrocytes. Many unanswered questions regarding the molecular mechanisms behind these changes can be addressed with high-resolution fluorescence imaging. Immunofluoresence staining enables localization of specific molecules, organelles, and membrane components in intact cells at different phases of erythropoiesis. Confocal laser scanning microscopy can provide high-resolution, three-dimensional images of stained structures, which can be used to dissect the molecular mechanisms driving erythropoiesis. The sample preparation, staining procedure, imaging parameters, and image analysis methods used directly affect the quality of the confocal images and the amount and accuracy of information that they can provide. Here, we describe methods to dissect erythropoietic tissues from mice, to perform immunofluorescence staining and confocal imaging of various molecules, organelles and structures of interest in erythroblasts, and to present and quantitatively analyze the data obtained in these fluorescence images.

  19. Sparse Recovery Analysis of High-Resolution Climate Data

    Science.gov (United States)

    Archibald, R.

    2013-12-01

    The field of compressed sensing is vast and currently very active, with new results, methods, and algorithms appearing almost daily. The first notions of compressed sensing began with Prony's method, which was designed by the French mathematician Gaspard Riche de Prony to extract signal information from a limited number of measurements. Since then, sparsity has been used empirically in a variety of applications, including geology and geophysics, spectroscopy, signal processing, radio astronomy, and medical ultrasound. High-resolution climate studies performed on large scale high performance computing have been producing large amounts of data that can benefit from unique mathematical methods for analysis. This work demonstrates how sparse recovery and L1 regularization can be used effectively on large datasets from high-resolution climate studies.

  20. Design of UAV high resolution image transmission system

    Science.gov (United States)

    Gao, Qiang; Ji, Ming; Pang, Lan; Jiang, Wen-tao; Fan, Pengcheng; Zhang, Xingcheng

    2017-02-01

    In order to solve the problem of the bandwidth limitation of the image transmission system on UAV, a scheme with image compression technology for mini UAV is proposed, based on the requirements of High-definition image transmission system of UAV. The video codec standard H.264 coding module and key technology was analyzed and studied for UAV area video communication. Based on the research of high-resolution image encoding and decoding technique and wireless transmit method, The high-resolution image transmission system was designed on architecture of Android and video codec chip; the constructed system was confirmed by experimentation in laboratory, the bit-rate could be controlled easily, QoS is stable, the low latency could meets most applied requirement not only for military use but also for industrial applications.

  1. A Procedure for High Resolution Satellite Imagery Quality Assessment

    Directory of Open Access Journals (Sweden)

    Mattia Crespi

    2009-05-01

    Full Text Available Data products generated from High Resolution Satellite Imagery (HRSI are routinely evaluated during the so-called in-orbit test period, in order to verify if their quality fits the desired features and, if necessary, to obtain the image correction parameters to be used at the ground processing center. Nevertheless, it is often useful to have tools to evaluate image quality also at the final user level. Image quality is defined by some parameters, such as the radiometric resolution and its accuracy, represented by the noise level, and the geometric resolution and sharpness, described by the Modulation Transfer Function (MTF. This paper proposes a procedure to evaluate these image quality parameters; the procedure was implemented in a suitable software and tested on high resolution imagery acquired by the QuickBird, WorldView-1 and Cartosat-1 satellites.

  2. Scalable, flexible and high resolution patterning of CVD graphene.

    Science.gov (United States)

    Hofmann, Mario; Hsieh, Ya-Ping; Hsu, Allen L; Kong, Jing

    2014-01-07

    The unique properties of graphene make it a promising material for interconnects in flexible and transparent electronics. To increase the commercial impact of graphene in those applications, a scalable and economical method for producing graphene patterns is required. The direct synthesis of graphene from an area-selectively passivated catalyst substrate can generate patterned graphene of high quality. We here present a solution-based method for producing patterned passivation layers. Various deposition methods such as ink-jet deposition and microcontact printing were explored, that can satisfy application demands for low cost, high resolution and scalable production of patterned graphene. The demonstrated high quality and nanometer precision of grown graphene establishes the potential of this synthesis approach for future commercial applications of graphene. Finally, the ability to transfer high resolution graphene patterns onto complex three-dimensional surfaces affords the vision of graphene-based interconnects in novel electronics.

  3. Space to Think: Large, High-Resolution Displays for Sensemaking

    Energy Technology Data Exchange (ETDEWEB)

    Andrews, Christopher P.; Endert, Alexander; North, Chris

    2010-05-05

    Space supports human cognitive abilities in a myriad of ways. The note attached to the side of the monitor, the papers spread out on the desk, diagrams scrawled on a whiteboard, and even the keys left out on the counter are all examples of using space to recall, reveal relationships, and think. Technological advances have made it possible to construct large display environments in which space has real meaning. This paper examines how increased space affects the way displays are regarded and used within the context of the cognitively demanding task of sensemaking. A study was conducted observing analysts using a prototype large, high-resolution display to solve an analytic problem. This paper reports on the results of this study and suggests a number of potential design criteria for future sensemaking tools developed for large, high-resolution displays.

  4. Automated data processing of high-resolution mass spectra

    DEFF Research Database (Denmark)

    Hansen, Michael Adsetts Edberg; Smedsgaard, Jørn

    infusion of crude extracts into the source taking advantage of the high sensitivity, high mass resolution and accuracy and the limited fragmentation. Unfortunately, there has not been a comparable development in the data processing techniques to fully exploit gain in high resolution and accuracy...... of the massive amounts of data. We present an automated data processing method to quantitatively compare large numbers of spectra from the analysis of complex mixtures, exploiting the full quality of high-resolution mass spectra. By projecting all detected ions - within defined intervals on both the time...... infusion analyses of crude extract to find the relationship between species from several species terverticillate Penicillium, and also that the ions responsible for the segregation can be identified. Furthermore the process can automate the process of detecting unique species and unique metabolites....

  5. High-resolution dynamical modelling of the Antarctic stratospheric vortex

    Science.gov (United States)

    Haynes, P. H.

    1988-01-01

    Progress is reported on the high-resolution three-dimensional numerical simulation of flows characteristic of the Antarctic wintertime stratosphere. The numerical model is a modified version of the Reading University sigma-coordinate used previously for tropospheric studies. Physical parameterizations are kept to a minimum in order to concentrate as much computing power as possible on simulating details of the dynamical processes. The major question addressed is whether the features observed in recent high-resolution two-dimensional simulations - namely: (1) the formation of a sharp edge to the vortex (seen in the potential vorticity field), (2) the survival of the polar vortex in a material entity, and (3) the formation of small-scale eddies rough the break-up of tongues of high potential vorticity drawn out from the polar vortex - are realized in three-dimensional simulations.

  6. Quantitative High-Resolution Transmission Electron Microscopy of Single Atoms

    OpenAIRE

    Gamm, B.; Popescu, R.; Blank, H.; Schneider, R; Beyer, A.; Gölzhäuser, A.; Gerthsen, D.

    2010-01-01

    Single atoms can be considered as basic objects for electron microscopy to test the microscope performance and basic concepts for modeling of image contrast. In this work high-resolution transmission electron microscopy was applied to image single platinum atoms in an aberration-corrected transmission electron microscope. The atoms are deposited on a self-assembled monolayer substrate which induces only negligible contrast. Single-atom contrast simulations were performed on the basis of Weick...

  7. High-resolution Imaging Techniques for the Assessment of Osteoporosis

    OpenAIRE

    Krug, Roland; Burghardt, Andrew J.; Majumdar, Sharmila; Link, Thomas M.

    2010-01-01

    The importance of assessing the bone’s microarchitectural make-up in addition to its mineral density in the context of osteoporosis has been emphasized in a number of publications. The high spatial resolution required to resolve the bone’s microstructure in a clinically feasible scan time is challenging. Currently, the best suited modalities meeting these requirements in vivo are high-resolution peripheral quantitative imaging (HR-pQCT) and magnetic resonance imaging (MRI). Whereas HR-pQCT is...

  8. Concept for a new high resolution high intensity diffractometer

    Energy Technology Data Exchange (ETDEWEB)

    Stuhr, U. [Paul Scherrer Inst. (PSI), Villigen (Switzerland)

    1997-09-01

    A concept of a new time-of-flight powder-diffractometer for a thermal neutral beam tube at SINQ is presented. The design of the instrument optimises the contradictory conditions of high intensity and high resolution. The high intensity is achieved by using many neutron pulses simultaneously. By analysing the time-angle-pattern of the detected neutrons an assignment of the neutrons to a single pulse is possible. (author) 3 figs., tab., refs.

  9. A high resolution cavity BPM for the CLIC Test Facility

    CERN Document Server

    Chritin, N.; Soby, L.; Lunin, A.; Solyak, N.; Wendt, M.; Yakovlev, V.

    2012-01-01

    In frame of the development of a high resolution BPM system for the CLIC Main Linac we present the design of a cavity BPM prototype. It consists of a waveguide loaded dipole mode resonator and a monopole mode reference cavity, both operating at 15 GHz, to be compatible with the bunch frequencies at the CLIC Test Facility. Requirements, design concept, numerical analysis, and practical considerations are discussed.

  10. Automatic Matching of High Resolution Satellite Images Based on RFM

    OpenAIRE

    JI Shunping; YUAN Xiuxiao

    2016-01-01

    A matching method for high resolution satellite images based on RFM is presented.Firstly,the RFM parameters are used to predict the initial parallax of corresponding points and the prediction accuracy is analyzed.Secondly,the approximate epipolar equation is constructed based on projection tracking and its accuracy is analyzed.Thirdly,approximate 1D image matching is executed on pyramid images and least square matching on base images.At last RANSAC is imbedded to eliminate mis-matching points...

  11. Tuberculous otitis media: findings on high-resolution CT

    Energy Technology Data Exchange (ETDEWEB)

    Lungenschmid, D. [Dept. of Radiodiagnostics, University Hospital Innsbruck (Austria)]|[Dept. of Magnetic Resonance and Spectroscopy, University Hospital of Innsbruck (Austria); Buchberger, W. [Dept. of Radiodiagnostics, University Hospital Innsbruck (Austria)]|[Dept. of Magnetic Resonance and Spectroscopy, University Hospital of Innsbruck (Austria); Schoen, G. [Dept. of Radiodiagnostics, University Hospital Innsbruck (Austria); Schoepf, R. [Radiologic Inst., Landeck (Austria); Mihatsch, T. [Dept. of Oto-Rhino-Laryngology, University Hospital of Innsbruck (Austria); Birbamer, G. [Dept. of Magnetic Resonance and Spectroscopy, University Hospital of Innsbruck (Austria); Wicke, K. [Inst. of Computed Tomography, University Hospital of Innsbruck (Austria)

    1993-12-01

    We describe two cases of tuberculous otitis media studied with high-resolution computed tomography (CT). Findings included extensive soft tissue densities with fluid levels in the tympanic cavity, the antrum, the mastoid and petrous air cells. Multifocal bony erosions and reactive bone sclerosis were seen as well. CT proved valuable for planning therapy by accurately displaying the involvement of the various structures of the middle and inner ear. However, the specific nature of the disease could only be presumed. (orig.)

  12. High-Resolution Wind Measurements for Offshore Wind Energy Development

    Science.gov (United States)

    Nghiem, Son V.; Neumann, Gregory

    2011-01-01

    A mathematical transform, called the Rosette Transform, together with a new method, called the Dense Sampling Method, have been developed. The Rosette Transform is invented to apply to both the mean part and the fluctuating part of a targeted radar signature using the Dense Sampling Method to construct the data in a high-resolution grid at 1-km posting for wind measurements over water surfaces such as oceans or lakes.

  13. Acute pulmonary injury: high-resolution CT and histopathological spectrum

    Science.gov (United States)

    Obadina, E T; Torrealba, J M

    2013-01-01

    Acute lung injury usually causes hypoxaemic respiratory failure and acute respiratory distress syndrome (ARDS). Although diffuse alveolar damage is the hallmark of ARDS, other histopathological patterns of injury, such as acute and fibrinoid organising pneumonia, can be associated with acute respiratory failure. Acute eosinophilic pneumonia can also cause acute hypoxaemic respiratory failure and mimic ARDS. This pictorial essay reviews the high-resolution CT findings of acute lung injury and the correlative histopathological findings. PMID:23659926

  14. High Resolution Analysis of Copy Number Mutation in Breast Cancer

    Science.gov (United States)

    2005-05-01

    Pon , in Polysaccharides in Medic- copy number at high resolution throughout the other diseases, we must distinguish abnormal inal Applications, S...was determined to in- leles . In all experiments, there were a total of silico from the human genome sequence as- volve an interchromosomal duplication...well (3), although we do not explore that approach here. PON ) = e -pb o#regular( - )#deviated [1] The negative log likelihood function satisfies an

  15. High Resolution Wavenumber Standards for the Infrared. (IUPAC Recommendations 1995)

    Science.gov (United States)

    Guelachvili, G.; Birk, M.; Bord, C.; Brault, J.; Brown, L.; Carli, B.; Cole, A.; Evenson, D.; Fayt, A.; Hausamann, D.; hide

    1995-01-01

    The calibration of high resolution infrared spectra is generally more precise than accurate even when they are recorded with Fourier interferometers. In order to improve the consistency of the spectral measurements, an IUPAC project has been undertaken. Its aim was to recommend a selection of spectral lines as wavenumber standards for absolute calibration in the infrared. This paper will report the final recommendations in the spectral range extending from about 4 to about 7000 cm(be).

  16. Validation of AIRS high-resolution stratospheric temperature retrievals

    Science.gov (United States)

    Meyer, Catrin I.; Hoffmann, Lars

    2014-10-01

    This paper focuses on stratospheric temperature observations by the Atmospheric InfraRed Sounder (AIRS) aboard NASA's Aqua satellite. We validate a nine-year record (2003 - 2011) of data retrieved with a scientific retrieval processor independent from the operational processor operated by NASA. The retrieval discussed here provides stratospheric temperature profiles for each individual AIRS footprint and has nine times better horizontal sampling than the operational data provided by NASA. The high-resolution temperature data are considered optimal for for gravity wave studies. For validation the high-resolution retrieval data are compared with results from the AIRS operational Level-2 data and the ERA-Interim meteorological reanalysis. Due to the large amount of data we performed statistical comparisons of monthly zonal mean cross-sections and time series. The comparisons show that the high-resolution temperature data are in good agreement with the validation data sets. The bias in the zonal averages is mostly within ±2K. The bias reaches a maximum of 7K to ERA-Interim and 4K to the AIRS operational data at the stratopause, it is related to the different resolutions of the data sets. Variability is nearly the same in all three data sets, having maximum standard deviations around the polar vortex in the mid and upper stratosphere. The validation presented here indicates that the high-resolution temperature retrievals are well-suited for scientific studies. In particular, we expect that they will become a valuable asset for future studies of stratospheric gravity waves.

  17. High-resolution x-ray photoemission spectra of silver

    DEFF Research Database (Denmark)

    Barrie, A.; Christensen, N. E.

    1976-01-01

    An electron spectrometer fitted with an x-ray monochromator for Al Kα1,2 radiation (1486.6 eV) has been used to record high-resolution x-ray photoelectron spectra for the 4d valence band as well as the 3d spin doublet in silver. The core-level spectrum has a line shape that can be described...

  18. High Resolution Measurements and Electronic Structure Calculations of a Diazanaphthalene

    Science.gov (United States)

    Gruet, Sébastien; Goubet, Manuel; Pirali, Olivier

    2014-06-01

    Polycyclic Aromatic Hydrocarbons (PAHs) have long been suspected to be the carriers of so called Unidentified Infrared Bands (UIBs). Most of the results published in the literature report rotationally unresolved spectra of pure carbon as well as heteroatom-containing PAHs species. To date for this class of molecules, the principal source of rotational informations is ruled by microwave (MW) spectroscopy while high resolution measurements reporting rotational structure of the infrared (IR) vibrational bands are very scarce. Recently, some high resolution techniques provided interesting new results to rotationally resolve the IR and far-IR bands of these large carbonated molecules of astrophysical interest. One of them is to use the bright synchrotron radiation as IR continuum source of a high resolution Fourier transform (FTIR) spectrometer. We report the very complementary analysis of the [1,6] naphthyridine (a N-bearing PAH) for which we recorded the microwave spectrum at the PhLAM laboratory (Lille) and the high resolution far-infrared spectrum on the AILES beamline at synchrotron facility SOLEIL. MW spectroscopy provided highly accurate rotational constants in the ground state to perform Ground State Combinations Differences (GSCD) allowing the analysis of the two most intense FT-FIR bands in the 50-900 wn range. Moreover, during this presentation the negative value of the inertial defect in the GS of the molecule will be discussed. A. Leger, J. L. Puget, Astron. Astrophys. 137, L5-L8 (1984) L. J. Allamandola et al. Astrophys. J. 290, L25-L28 (1985). Z. Kisiel et al. J. Mol. Spectrosc. 217, 115 (2003) S. Thorwirth et al. Astrophys. J. 662, 1309 (2007) D. McNaughton et al. J. Chem. Phys. 124, 154305 (2011). S. Albert et al. Faraday Discuss. 150, 71-99 (2011) B. E. Brumfield et al. Phys. Chem. Lett. 3, 1985-1988 (2012) O. Pirali et al. Phys. Chem. Chem. Phys. 15, 10141 (2013).

  19. High-resolution neutron microtomography with noiseless neutron counting detector

    Science.gov (United States)

    Tremsin, A. S.; McPhate, J. B.; Vallerga, J. V.; Siegmund, O. H. W.; Feller, W. B.; Lehmann, E.; Butler, L. G.; Dawson, M.

    2011-10-01

    The improved collimation and intensity of thermal and cold neutron beamlines combined with recent advances in neutron imaging devices enable high-resolution neutron radiography and microtomography, which can provide information on the internal structure of objects not achievable with conventional X-ray imaging techniques. Neutron detection efficiency, spatial and temporal resolution (important for the studies of dynamic processes) and low background count rate are among the crucial parameters defining the quality of radiographic images and tomographic reconstructions. The unique capabilities of neutron counting detectors with neutron-sensitive microchannel plates (MCPs) and with Timepix CMOS readouts providing high neutron detection efficiency (˜70% for cold neutrons), spatial resolutions ranging from 15 to 55 μm and a temporal resolution of ˜1 μs—combined with the virtual absence of readout noise—make these devices very attractive for high-resolution microtomography. In this paper we demonstrate the capabilities of an MCP-Timepix detection system applied to microtomographic imaging, performed at the ICON cold neutron facility of the Paul Scherrer Institute. The high resolution and the absence of readout noise enable accurate reconstruction of texture in a relatively opaque wood sample, differentiation of internal tissues of a fly and imaging of individual ˜400 μm grains in an organic powder encapsulated in a ˜700 μm thick metal casing.

  20. High-resolution CT findings in Streptococcus milleri pulmonary infection.

    Science.gov (United States)

    Okada, F; Ono, A; Ando, Y; Nakayama, T; Ishii, H; Hiramatsu, K; Sato, H; Kira, A; Otabe, M; Mori, H

    2013-06-01

    To assess pulmonary high-resolution computed tomography (CT) findings in patients with acute Streptococcus milleri pulmonary infection. Sixty consecutive patients with acute S. milleri pneumonia who had undergone high-resolution CT chest examinations between January 2004 and March 2010 were retrospectively identified. Twenty-seven patients with concurrent infections were excluded. The final study group comprised 33 patients (25 men, 8 women; aged 20-88 years, mean 63.1 years) with S. milleri infection. The patients' clinical findings were assessed. Parenchymal abnormalities, enlarged lymph nodes, and pleural effusion were evaluated on high-resolution CT. Underlying conditions included malignancy (n = 15), a smoking habit (n = 11), and diabetes mellitus (n = 8). CT images of all patients showed abnormal findings, including ground-glass opacity (n = 24), bronchial wall thickening (n = 23), consolidation (n = 17), and cavities (n = 7). Pleural effusion was found in 18 patients, and complex pleural effusions were found in seven patients. Pulmonary infection caused by S. milleri was observed mostly in male patients with underlying conditions such as malignancy or a smoking habit. The CT findings in patients with S. milleri consisted mainly of ground-glass opacity, bronchial wall thickening, pleural effusions, and cavities. Copyright © 2013 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

  1. Progress in high-resolution x-ray holographic microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Jacobsen, C.; Kirz, J.; Howells, M.; McQuaid, K.; Rothman, S.; Feder, R.; Sayre, D.

    1987-07-01

    Among the various types of x-ray microscopes that have been demonstrated, the holographic microscope has had the largest gap between promise and performance. The difficulties of fabricating x-ray optical elements have led some to view holography as the most attractive method for obtaining the ultimate in high resolution x-ray micrographs; however, we know of no investigations prior to 1987 that clearly demonstrated submicron resolution in reconstructed images. Previous efforts suffered from problems such as limited resolution and dynamic range in the recording media, low coherent x-ray flux, and aberrations and diffraction limits in visible light reconstruction. We have addressed the recording limitations through the use of an undulator x-ray source and high-resolution photoresist recording media. For improved results in the readout and reconstruction steps, we have employed metal shadowing and transmission electron microscopy, along with numerical reconstruction techniques. We believe that this approach will allow holography to emerge as a practical method of high-resolution x-ray microscopy. 30 refs., 4 figs.

  2. Adaptive optics with pupil tracking for high resolution retinal imaging.

    Science.gov (United States)

    Sahin, Betul; Lamory, Barbara; Levecq, Xavier; Harms, Fabrice; Dainty, Chris

    2012-02-01

    Adaptive optics, when integrated into retinal imaging systems, compensates for rapidly changing ocular aberrations in real time and results in improved high resolution images that reveal the photoreceptor mosaic. Imaging the retina at high resolution has numerous potential medical applications, and yet for the development of commercial products that can be used in the clinic, the complexity and high cost of the present research systems have to be addressed. We present a new method to control the deformable mirror in real time based on pupil tracking measurements which uses the default camera for the alignment of the eye in the retinal imaging system and requires no extra cost or hardware. We also present the first experiments done with a compact adaptive optics flood illumination fundus camera where it was possible to compensate for the higher order aberrations of a moving model eye and in vivo in real time based on pupil tracking measurements, without the real time contribution of a wavefront sensor. As an outcome of this research, we showed that pupil tracking can be effectively used as a low cost and practical adaptive optics tool for high resolution retinal imaging because eye movements constitute an important part of the ocular wavefront dynamics.

  3. Sharpening high resolution information in single particle electron cryomicroscopy.

    Science.gov (United States)

    Fernández, J J; Luque, D; Castón, J R; Carrascosa, J L

    2008-10-01

    Advances in single particle electron cryomicroscopy have made possible to elucidate routinely the structure of biological specimens at subnanometer resolution. At this resolution, secondary structure elements are discernable by their signature. However, identification and interpretation of high resolution structural features are hindered by the contrast loss caused by experimental and computational factors. This contrast loss is traditionally modeled by a Gaussian decay of structure factors with a temperature factor, or B-factor. Standard restoration procedures usually sharpen the experimental maps either by applying a Gaussian function with an inverse ad hoc B-factor, or according to the amplitude decay of a reference structure. EM-BFACTOR is a program that has been designed to widely facilitate the use of the novel method for objective B-factor determination and contrast restoration introduced by Rosenthal and Henderson [Rosenthal, P.B., Henderson, R., 2003. Optimal determination of particle orientation, absolute hand, and contrast loss in single-particle electron cryomicroscopy. J. Mol. Biol. 333, 721-745]. The program has been developed to interact with the most common packages for single particle electron cryomicroscopy. This sharpening method has been further investigated via EM-BFACTOR, concluding that it helps to unravel the high resolution molecular features concealed in experimental density maps, thereby making them better suited for interpretation. Therefore, the method may facilitate the analysis of experimental data in high resolution single particle electron cryomicroscopy.

  4. Glacial lake mapping with very high resolution satellite SAR data

    Science.gov (United States)

    Strozzi, T.; Wiesmann, A.; Kääb, A.; Joshi, S.; Mool, P.

    2012-08-01

    Floods resulting from the outbursts of glacial lakes are among the most far-reaching disasters in high mountain regions. Glacial lakes are typically located in remote areas and space-borne remote sensing data are an important source of information about the occurrence and development of such lakes. Here we show that very high resolution satellite Synthetic Aperture Radar (SAR) data can be employed for reliably mapping glacial lakes. Results in the Alps, Pamir and Himalaya using TerraSAR-X and Radarsat-2 data are discussed in comparison to in-situ information, and high-resolution satellite optical and radar imagery. The performance of the satellite SAR data is best during the snow- and ice-free season. In the broader perspective of hazard management, the detection of glacial lakes and the monitoring of their changes from very high-resolution satellite SAR intensity images contributes to the initial assessment of hazards related to glacial lakes, but a more integrated, multi-level approach needs also to include other relevant information such as glacier outlines and outline changes or the identification of unstable slopes above the lake and the surrounding area, information types to which SAR analysis techniques can also contribute.

  5. High Resolution Observations of Escaping Ions in the Martian Magnetotail

    Science.gov (United States)

    Halekas, J. S.; Raman, C.; Brain, D.; DiBraccio, G. A.; Harada, Y.; McFadden, J. P.; Mitchell, D. L.; Connerney, J. E. P.; Jakosky, B. M.

    2016-12-01

    Ions escape from the Martian upper atmosphere via a number of channels, including the central plasmasheet of the magnetotail. Mars Express observations show that the heavy ions O+ and O2+ escaping through the central tail often have approximately the same energy, suggesting acceleration in a quasi-static electric field, which has been interpreted as a Hall electric field. The Solar Wind Ion Analyzer (SWIA) on MAVEN was designed to measure the upstream solar wind. However, during orbit segments with appropriate spacecraft attitude, SWIA can also make high resolution measurements of escaping ions in the tail. During the prime mission, these observations were only returned sporadically, during periods of intense escaping fluxes that fortuitously triggered a mode switch. Now, in the extended mission, we return high resolution observations from SWIA routinely. Some of these high resolution measurements reveal slight differences in both the direction and energy of escaping O+ and O2+ ions, which may help determine the acceleration process(es). We investigate the location and solar wind conditions for which the escaping ions separate in energy and angle and the systematics of their energies and flow vectors, and discuss the implications for ion acceleration and the overall picture of Martian atmospheric escape.

  6. High resolution, MRI-based, segmented, computerized head phantom

    Energy Technology Data Exchange (ETDEWEB)

    Zubal, I.G.; Harrell, C.R.; Smith, E.O.; Smith, A.L.; Krischlunas, P. [Yale Univ., New Haven, CT (United States). Dept. of Diagnostic Radiology

    1999-01-01

    The authors have created a high-resolution software phantom of the human brain which is applicable to voxel-based radiation transport calculations yielding nuclear medicine simulated images and/or internal dose estimates. A software head phantom was created from 124 transverse MRI images of a healthy normal individual. The transverse T2 slices, recorded in a 256x256 matrix from a GE Signa 2 scanner, have isotropic voxel dimensions of 1.5 mm and were manually segmented by the clinical staff. Each voxel of the phantom contains one of 62 index numbers designating anatomical, neurological, and taxonomical structures. The result is stored as a 256x256x128 byte array. Internal volumes compare favorably to those described in the ICRP Reference Man. The computerized array represents a high resolution model of a typical human brain and serves as a voxel-based anthropomorphic head phantom suitable for computer-based modeling and simulation calculations. It offers an improved realism over previous mathematically described software brain phantoms, and creates a reference standard for comparing results of newly emerging voxel-based computations. Such voxel-based computations lead the way to developing diagnostic and dosimetry calculations which can utilize patient-specific diagnostic images. However, such individualized approaches lack fast, automatic segmentation schemes for routine use; therefore, the high resolution, typical head geometry gives the most realistic patient model currently available.

  7. Adaptive optics high resolution spectroscopy: present status and future direction

    Energy Technology Data Exchange (ETDEWEB)

    Alcock, C; Angel, R; Ciarlo, D; Fugate, R O; Ge, J; Kuzmenko, P; Lloyd-Hart, M; Macintosh, B; Najita, J; Woolf, N

    1999-07-27

    High resolution spectroscopy experiments with visible adaptive optics (AO) telescopes at Starfire Optical Range and Mt. Wilson have demonstrated that spectral resolution can be routinely improved by a factor of - 10 over the seeing-limited case with no extra light losses at visible wavelengths. With large CCDs now available, a very wide wavelength range can be covered in a single exposure. In the near future, most large ground-based telescopes will be equipped with powerful A0 systems. Most of these systems are aimed primarily at diffraction-limited operation in the near IR. An exciting new opportunity will thus open up for high resolution IR spectroscopy. Immersion echelle gratings with much coarser grooves being developed by us at LLNL will play a critical role in achieving high spectral resolution with a compact and low cost IR cryogenically cooled spectrograph and simultaneous large wavelength coverage on relatively small IR detectors. We have constructed a new A0 optimized spectrograph at Steward Observatory to provide R = 200,000 in the optical, which is being commissioned at the Starfire Optical Range 3.5m telescope. We have completed the optical design of the LLNL IR Immersion Spectrograph (LISPEC) to take advantage of improved silicon etching technology. Key words: adaptive optics, spectroscopy, high resolution, immersion gratings

  8. Climatologies at high resolution for the earth's land surface areas

    Science.gov (United States)

    Karger, Dirk Nikolaus; Conrad, Olaf; Böhner, Jürgen; Kawohl, Tobias; Kreft, Holger; Soria-Auza, Rodrigo Wilber; Zimmermann, Niklaus E.; Linder, H. Peter; Kessler, Michael

    2017-09-01

    High-resolution information on climatic conditions is essential to many applications in environmental and ecological sciences. Here we present the CHELSA (Climatologies at high resolution for the earth's land surface areas) data of downscaled model output temperature and precipitation estimates of the ERA-Interim climatic reanalysis to a high resolution of 30 arc sec. The temperature algorithm is based on statistical downscaling of atmospheric temperatures. The precipitation algorithm incorporates orographic predictors including wind fields, valley exposition, and boundary layer height, with a subsequent bias correction. The resulting data consist of a monthly temperature and precipitation climatology for the years 1979-2013. We compare the data derived from the CHELSA algorithm with other standard gridded products and station data from the Global Historical Climate Network. We compare the performance of the new climatologies in species distribution modelling and show that we can increase the accuracy of species range predictions. We further show that CHELSA climatological data has a similar accuracy as other products for temperature, but that its predictions of precipitation patterns are better.

  9. High-resolution flood modeling of urban areas using MSN_Flood

    Directory of Open Access Journals (Sweden)

    Michael Hartnett

    2017-07-01

    Full Text Available Although existing hydraulic models have been used to simulate and predict urban flooding, most of these models are inadequate due to the high spatial resolution required to simulate flows in urban floodplains. Nesting high-resolution subdomains within coarser-resolution models is an efficient solution for enabling simultaneous calculation of flooding due to tides, surges, and high river flows. MSN_Flood has been developed to incorporate moving boundaries around nested domains, permitting alternate flooding and drying along the boundary and in the interior of the domain. Ghost cells adjacent to open boundary cells convert open boundaries, in effect, into internal boundaries. The moving boundary may be multi-segmented and non-continuous, with recirculating flow across the boundary. When combined with a bespoke adaptive interpolation scheme, this approach facilitates a dynamic internal boundary. Based on an alternating-direction semi-implicit finite difference scheme, MSN_Flood was used to hindcast a major flood event in Cork City resulting from the combined pressures of fluvial, tidal, and storm surge processes. The results show that the model is computationally efficient, as the 2-m high-resolution nest is used only in the urban flooded region. Elsewhere, lower-resolution nests are used. The results also show that the model is highly accurate when compared with measured data. The model is capable of incorporating nested sub-domains when the nested boundary is multi-segmented and highly complex with lateral gradients of elevation and velocities. This is a major benefit when modelling urban floodplains at very high resolution.

  10. High resolution and stability roll angle measurement method for precision linear displacement stages

    Science.gov (United States)

    Jin, Tao; Xia, Guizheng; Hou, Wenmei; Le, Yanfen; Han, Sen

    2017-02-01

    A method for high resolution roll angle measurement of linear displacement stages is developed theoretically and tested experimentally. The new optical configuration is based on a special differential plane mirror interferometer, a wedge prism assembly, and a wedge mirror assembly. The wedge prisms assembly is used as a roll angle sensor, which converts roll angle to the changes of optical path. The special interferometer, composed a polarization splitter plane, a half wave plate, a beam splitter, a retro-reflector and a quarter wave plate, is designed for high resolution measurement of the changes of the optical path. The interferometric beams are a completely common path for the adoption of the centrosymmetrical measurement structure, and the cross talk of the straightness, yaw, and pitch errors is avoided. The angle measurement resolution of the proposed method is 3.5 μrad in theoretical with a phase meter which has a resolution of 2 π /512 . The experimental result also shows the great stability and accuracy of the present roll angle measurement system.

  11. Object-based Morphological Building Index for Building Extraction from High Resolution Remote Sensing Imagery

    Directory of Open Access Journals (Sweden)

    LIN Xiangguo

    2017-06-01

    Full Text Available Building extraction from high resolution remote sensing images is a hot research topic in the field of photogrammetry and remote sensing. In this article, an object-based morphological building index (OBMBI is constructed based on both image segmentation and graph-based top-hat reconstruction, and OBMBI is used for building extraction from high resolution remote sensing images. First, bidirectional mapping relationship between pixels, objects and graph-nodes are constructed. Second, the OBMBI image is built based on both graph-based top-hat reconstruction and the above mapping relationship. Third, a binary thresholding is performed on the OBMBI image, and the binary image is converted into vector format to derive the building polygons. Finally, the post-processing is made to optimize the extracted building polygons. Two images, including an aerial image and a panchromatic satellite image, are used to test both the proposed method and classic PanTex method. The experimental results suggest that our proposed method has a higher accuracy in building extraction than the classic PanTex method. On average, the correctness, the completeness and the quality of our method are respectively 9.49%, 11.26% and 14.11% better than those of the PanTex.

  12. High resolution solar observations from first principles to applications

    Science.gov (United States)

    Verdoni, Angelo P.

    2009-10-01

    The expression "high-resolution observations" in Solar Physics refers to the spatial, temporal and spectral domains in their entirety. High-resolution observations of solar fine structure are a necessity to answer many of the intriguing questions related to solar activity. However, a researcher building instruments for high-resolution observations has to cope with the fact that these three domains often have diametrically opposed boundary conditions. Many factors have to be considered in the design of a successful instrument. Modern post-focus instruments are more closely linked with the solar telescopes that they serve than in past. In principle, the quest for high-resolution observations already starts with the selection of the observatory site. The site survey of the Advanced Technology Solar Telescope (ATST) under the stewardship of the National Solar Observatory (NSO) has identified Big Bear Solar Observatory (BBSO) as one of the best sites for solar observations. In a first step, the seeing characteristics at BBSO based on the data collected for the ATST site survey are described. The analysis will aid in the scheduling of high-resolution observations at BBSO as well as provide useful information concerning the design and implementation of a thermal control system for the New Solar Telescope (NST). NST is an off-axis open-structure Gregorian-style telescope with a 1.6 m aperture. NST will be housed in a newly constructed 5/8-sphere ventilated dome. With optics exposed to the surrounding air, NST's open-structure design makes it particularly vulnerable to the effects of enclosure-related seeing. In an effort to mitigate these effects, the initial design of a thermal control system for the NST dome is presented. The goal is to remediate thermal related seeing effects present within the dome interior. The THermal Control System (THCS) is an essential component for the open-telescope design of NST to work. Following these tasks, a calibration routine for the

  13. Proceedings of the workshop on high resolution computed microtomography (CMT)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-02-01

    The purpose of the workshop was to determine the status of the field, to define instrumental and computational requirements, and to establish minimum specifications required by possible users. The most important message sent by implementers was the remainder that CMT is a tool. It solves a wide spectrum of scientific problems and is complementary to other microscopy techniques, with certain important advantages that the other methods do not have. High-resolution CMT can be used non-invasively and non-destructively to study a variety of hierarchical three-dimensional microstructures, which in turn control body function. X-ray computed microtomography can also be used at the frontiers of physics, in the study of granular systems, for example. With high-resolution CMT, for example, three-dimensional pore geometries and topologies of soils and rocks can be obtained readily and implemented directly in transport models. In turn, these geometries can be used to calculate fundamental physical properties, such as permeability and electrical conductivity, from first principles. Clearly, use of the high-resolution CMT technique will contribute tremendously to the advancement of current R and D technologies in the production, transport, storage, and utilization of oil and natural gas. It can also be applied to problems related to environmental pollution, particularly to spilling and seepage of hazardous chemicals into the Earth's subsurface. Applications to energy and environmental problems will be far-ranging and may soon extend to disciplines such as materials science--where the method can be used in the manufacture of porous ceramics, filament-resin composites, and microelectronics components--and to biomedicine, where it could be used to design biocompatible materials such as artificial bones, contact lenses, or medication-releasing implants. Selected papers are indexed separately for inclusion in the Energy Science and Technology Database.

  14. Measuring Large-Scale Social Networks with High Resolution

    DEFF Research Database (Denmark)

    Stopczynski, Arkadiusz; Sekara, Vedran; Sapiezynski, Piotr

    2014-01-01

    , telecommunication, social networks, location, and background information (personality, demographics, health, politics) for a densely connected population of 1 000 individuals, using state-of-the-art smartphones as social sensors. Here we provide an overview of the related work and describe the motivation...... and research agenda driving the study. Additionally, the paper details the data-types measured, and the technical infrastructure in terms of both backend and phone software, as well as an outline of the deployment procedures. We document the participant privacy procedures and their underlying principles....... The paper is concluded with early results from data analysis, illustrating the importance of multi-channel high-resolution approach to data collection....

  15. High resolution wind turbine wake measurements with a scanning lidar

    DEFF Research Database (Denmark)

    Herges, T. G.; Maniaci, D. C.; Naughton, B. T.

    2017-01-01

    High-resolution lidar wake measurements are part of an ongoing field campaign being conducted at the Scaled Wind Farm Technology facility by Sandia National Laboratories and the National Renewable Energy Laboratory using a customized scanning lidar from the Technical University of Denmark. One...... of the primary objectives is to collect experimental data to improve the predictive capability of wind plant computational models to represent the response of the turbine wake to varying inflow conditions and turbine operating states. The present work summarizes the experimental setup and illustrates several...

  16. High-resolution AMLCD for the electronic library system

    Science.gov (United States)

    Martin, Russel A.; Middo, Kathy; Turner, William D.; Lewis, Alan; Thompson, Malcolm J.; Silverstein, Louis D.

    1994-06-01

    The Electronic Library System (ELS), is a proposed data resource for the cockpit which can provide the aircrew with a vast array of technical information on their aircraft and flight plan. This information includes, but is not limited to, approach plates, Jeppeson Charts, and aircraft technical manuals. Most of these data are appropriate for digitization at high resolution (300 spi). Xerox Corporation has developed a flat panel active matrix liquid crystal display, AMLCD, that is an excellent match to the ELS, due to its innovative and aggressive design.

  17. High resolution study of magnetic ordering at absolute zero.

    Science.gov (United States)

    Lee, M; Husmann, A; Rosenbaum, T F; Aeppli, G

    2004-05-07

    High resolution pressure measurements in the zero-temperature limit provide a unique opportunity to study the behavior of strongly interacting, itinerant electrons with coupled spin and charge degrees of freedom. Approaching the precision that has become the hallmark of experiments on classical critical phenomena, we characterize the quantum critical behavior of the model, elemental antiferromagnet chromium, lightly doped with vanadium. We resolve the sharp doubling of the Hall coefficient at the quantum critical point and trace the dominating effects of quantum fluctuations up to surprisingly high temperatures.

  18. High-Resolution Reciprocal Space Mapping for Characterizing Deformation Structures

    DEFF Research Database (Denmark)

    Pantleon, Wolfgang; Wejdemann, Christian; Jakobsen, Bo

    2014-01-01

    With high-angular resolution three-dimensional X-ray diffraction (3DXRD), quantitative information is gained about dislocation structures in individual grains in the bulk of a macroscopic specimen by acquiring reciprocal space maps. In high-resolution 3D reciprocal space maps of tensile...... dynamics is followed in situ during varying loading conditions by reciprocal space mapping: during uninterrupted tensile deformation, formation of subgrains is observed concurrently with broadening of Bragg reflections shortly after the onset of plastic deformation. When the traction is terminated, stress...

  19. High resolution X-ray spectroscopy in light antiprotonic atoms

    CERN Document Server

    Borchert, G L; Augsburger, M A; Castelli, C M; Chatellard, D; Egger, J P; El-Khoury, P; Elble, M; Gorke, H; Gotta, D; Hauser, P R; Indelicato, P J; Kirch, K; Lenz, S; Nelms, N; Rashid, K; Schult, O W B; Siems, T; Simons, L M

    2000-01-01

    At the LEAR facility, CERN, antiprotonic L alpha transitions in light elements have been investigated with a focussing crystal spectrometer. The high resolution of the experiment allowed for the first time to resolve in pH/pH the 2/sup 3/P/sub 0/ state from the close-lying states 2/sup 3/P/sub 2/, 2/sup 1/P/sub 1/, and 2/sup 3/P /sub 1/. In pD the corresponding transitions were found to be more than an order of magnitude broader. To a large extent the results for pH support the meson exchange model. (15 refs).

  20. Laser ablated hydantoin: A high resolution rotational study

    Science.gov (United States)

    Alonso, Elena R.; Kolesniková, Lucie; Alonso, José L.

    2017-09-01

    Laser ablation techniques coupled with broadband and narrowband Fourier transform microwave spectroscopies have allowed the high resolution rotational study of solid hydantoin, an important target in astrochemistry as a possible precursor of glycine. The complicated hyperfine structure arising from the presence of two 14N nuclei in non-equivalent positions has been resolved and interpreted in terms of the nuclear quadrupole coupling interactions. The results reported in this work provide a solid base for the interstellar searches of hydantoin in the astrophysical surveys. The values of the nuclear quadrupole coupling constants have been also discussed in terms of the electronic environment around the respective nitrogen atom.

  1. High Resolution-Resonance Ionization Spectroscopy on uranium

    Energy Technology Data Exchange (ETDEWEB)

    Hakimi, Amin, E-mail: hakimi@uni-mainz.de; Fischbach, Thomas [Johannes Gutenberg-Universitaet Mainz, Institut fuer Physik (Germany); Raeder, Sebastian [TRIUMF (Canada); Trautmann, Norbert [Johannes Gutenberg-Universitaet Mainz, Institut fuer Kernchemie (Germany); Wendt, Klaus [Johannes Gutenberg-Universitaet Mainz, Institut fuer Physik (Germany)

    2013-04-15

    High Resolution-Resonance Ionization Spectroscopy (HR-RIS) allows for sensitive probing of atomic structures and energy level schemes even for highly complex systems. This work explores the applicability of commercial diode lasers for isotope selective spectroscopy of uranium. Using narrow bandwidth continuous-wave (cw) diode lasers, multi step excitation processes were investigated involving levels which could be populated with the radiation of 405 nm BluRay{sup Copyright-Sign} laser diodes as a first step for ultra trace analysis of uranium.

  2. Invited article: High resolution digital camera for infrared reflectography.

    Science.gov (United States)

    Falco, Charles M

    2009-07-01

    This paper describes the characteristics of a high resolution infrared (IR) imaging system operating over the wavelength range of 830-1100 nm, based on a modified 8 Mpixels commercial digital camera, with which nonspecialists can obtain IR reflectograms of works of art in situ in a museum environment. The relevant imaging properties of sensitivity, resolution, noise, and contrast are characterized and the capabilities of this system are illustrated with an example that has revealed important new information about the working practices of a 16th century artist.

  3. Achieving High Resolution Timer Events in Virtualized Environment.

    Science.gov (United States)

    Adamczyk, Blazej; Chydzinski, Andrzej

    2015-01-01

    Virtual Machine Monitors (VMM) have become popular in different application areas. Some applications may require to generate the timer events with high resolution and precision. This however may be challenging due to the complexity of VMMs. In this paper we focus on the timer functionality provided by five different VMMs-Xen, KVM, Qemu, VirtualBox and VMWare. Firstly, we evaluate resolutions and precisions of their timer events. Apparently, provided resolutions and precisions are far too low for some applications (e.g. networking applications with the quality of service). Then, using Xen virtualization we demonstrate the improved timer design that greatly enhances both the resolution and precision of achieved timer events.

  4. High resolution projection micro stereolithography system and method

    Energy Technology Data Exchange (ETDEWEB)

    Spadaccini, Christopher M.; Farquar, George; Weisgraber, Todd; Gemberling, Steven; Fang, Nicholas; Xu, Jun; Alonso, Matthew; Lee, Howon

    2016-11-15

    A high-resolution P.mu.SL system and method incorporating one or more of the following features with a standard P.mu.SL system using a SLM projected digital image to form components in a stereolithographic bath: a far-field superlens for producing sub-diffraction-limited features, multiple spatial light modulators (SLM) to generate spatially-controlled three-dimensional interference holograms with nanoscale features, and the integration of microfluidic components into the resin bath of a P.mu.SL system to fabricate microstructures of different materials.

  5. Clickstream data yields high-resolution maps of science

    Energy Technology Data Exchange (ETDEWEB)

    Bollen, Johan [Los Alamos National Laboratory; Van De Sompel, Herbert [Los Alamos National Laboratory; Hagberg, Aric [Los Alamos National Laboratory; Bettencourt, Luis [Los Alamos National Laboratory; Chute, Ryan [Los Alamos National Laboratory; Rodriguez, Marko A [Los Alamos National Laboratory; Balakireva, Lyudmila [Los Alamos National Laboratory

    2009-01-01

    Intricate maps of science have been created from citation data to visualize the structure of scientific activity. However, most scientific publications are now accessed online. Scholarly web portals record detailed log data at a scale that exceeds the number of all existing citations combined. Such log data is recorded immediately upon publication and keeps track of the sequences of user requests (clickstreams) that are issued by a variety of users across many different domains. Given these advantagees of log datasets over citation data, we investigate whether they can produce high-resolution, more current maps of science.

  6. Tests of a High Resolution Beam Profile Monitor

    Energy Technology Data Exchange (ETDEWEB)

    Norem, J.

    2004-10-28

    High energy linear colliders require very small beams at the interaction point to produce high luminosities, and these beams must be measured and monitored. We have developed and tested a technique where the profile can be obtained from an extension of pinhole camera optics using thick, single sided collimators and slits. Very high resolutions (a few nm) should be possible. Gamma beams can be obtained from bremsstrahlung, Compton or beamstrahlung radiation. We describe tests of the technique using bremsstrahlung from an 800 MeV electron beam at Bates/MIT, Compton scattered photons from 47 GeV Final Focus Test Beam (FFTB) at SLAC, and other applications, such as linear colliders.

  7. High-resolution seismic wave propagation using local time stepping

    KAUST Repository

    Peter, Daniel

    2017-03-13

    High-resolution seismic wave simulations often require local refinements in numerical meshes to accurately capture e.g. steep topography or complex fault geometry. Together with explicit time schemes, this dramatically reduces the global time step size for ground-motion simulations due to numerical stability conditions. To alleviate this problem, local time stepping (LTS) algorithms allow an explicit time stepping scheme to adapt the time step to the element size, allowing nearoptimal time steps everywhere in the mesh. This can potentially lead to significantly faster simulation runtimes.

  8. High-resolution overtone spectra of molecular complexes

    Science.gov (United States)

    Didriche, K.; Földes, T.

    2013-02-01

    A high-resolution spectrum of the acetylene-water complex has been recorded in the overtone range. Two bands of C2H2-D2O were analysed, corresponding to the overtone excitations of either the acetylene or the water units. The vibrational shifts and the upper states rotational constants were retrieved, demonstrating that the geometry of the complex is only slightly modified by the excitation. A larger linewidth was observed for the 2CH band than for the 2OD + DOD band, probably due to the direct coupling of the 2CH excitation with the dissociation coordinate.

  9. High resolution skin colorimetry, strain mapping and mechanobiology.

    Science.gov (United States)

    Devillers, C; Piérard-Franchimont, C; Schreder, A; Docquier, V; Piérard, G E

    2010-08-01

    Skin colours are notoriously different between individuals. They are governed by ethnicities and phototypes, and further influenced by a variety of factors including photoexposures and sustained mechanical stress. Indeed, mechanobiology is a feature affecting the epidermal melanization. High-resolution epiluminescence colorimetry helps in deciphering the effects of forces generated by Langer's lines or relaxed skin tension lines on the melanocyte activity. The same procedure shows a prominent laddering pattern of melanization in striae distensae contrasting with the regular honeycomb pattern in the surrounding skin.

  10. Data Converter

    NARCIS (Netherlands)

    Schinkel, Daniel; Nuijten, Petrus A.C.M.

    2005-01-01

    A data converter comprises a discrete- time sigma delta modulator e.g. for driving a Class-D power amplifier. The low-pass filter of the sigma delta modulator is modified by adding a suitably positioned pole to lower the oscillation frequency (limit cycle) of the sigma delta modulator in order to

  11. Data Converter

    NARCIS (Netherlands)

    Schinkel, Daniel

    2005-01-01

    A data converter comprises a discrete-time sigma delta modulator e.g. for driving a Class-D power amplifier. The low-pass filter of the sigma delta modulator is modified by adding a suitably positioned pole to lower the oscillation frequency (limit cycle) of the sigma delta modulator in order to

  12. Data Converter

    NARCIS (Netherlands)

    Schinkel, Daniel

    2006-01-01

    A data converter comprises a discrete-time sigma delta modulator e.g. for driving a Class-D power amplifier. The low-pass filter of the sigma delta modulator is modified by adding a suitably positioned pole to lower the oscillation frequency (limit cycle) of the sigma delta modulator in order to

  13. High-resolution Imaging Techniques for the Assessment of Osteoporosis

    Science.gov (United States)

    Krug, Roland; Burghardt, Andrew J.; Majumdar, Sharmila; Link, Thomas M.

    2010-01-01

    Synopsis The importance of assessing the bone’s microarchitectural make-up in addition to its mineral density in the context of osteoporosis has been emphasized in a number of publications. The high spatial resolution required to resolve the bone’s microstructure in a clinically feasible scan time is challenging. Currently, the best suited modalities meeting these requirements in vivo are high-resolution peripheral quantitative imaging (HR-pQCT) and magnetic resonance imaging (MRI). Whereas HR-pQCT is limited to peripheral skeleton regions like the wrist and ankle, MRI can also image other sites like the proximal femur but usually with lower spatial resolution. In addition Multidetector-CT has been used for high-resolution imaging of trabecular bone structure, however, the radiation dose is a limiting factor. This article provides an overview of the different modalities, technical requirements and recent developments in this emerging field. Details regarding imaging protocols as well as image post-processing methods for bone structure quantification are discussed. PMID:20609895

  14. Differentiation of Staphylococcus spp. by high-resolution melting analysis.

    Science.gov (United States)

    Slany, Michal; Vanerkova, Martina; Nemcova, Eva; Zaloudikova, Barbora; Ruzicka, Filip; Freiberger, Tomas

    2010-12-01

    High-resolution melting analysis (HRMA) is a fast (post-PCR) high-throughput method to scan for sequence variations in a target gene. The aim of this study was to test the potential of HRMA to distinguish particular bacterial species of the Staphylococcus genus even when using a broad-range PCR within the 16S rRNA gene where sequence differences are minimal. Genomic DNA samples isolated from 12 reference staphylococcal strains (Staphylococcus aureus, Staphylococcus capitis, Staphylococcus caprae, Staphylococcus epidermidis, Staphylococcus haemolyticus, Staphylococcus hominis, Staphylococcus intermedius, Staphylococcus saprophyticus, Staphylococcus sciuri, Staphylococcus simulans, Staphylococcus warneri, and Staphylococcus xylosus) were subjected to a real-time PCR amplification of the 16S rRNA gene in the presence of fluorescent dye EvaGreen™, followed by HRMA. Melting profiles were used as molecular fingerprints for bacterial species differentiation. HRMA of S. saprophyticus and S. xylosus resulted in undistinguishable profiles because of their identical sequences in the analyzed 16S rRNA region. The remaining reference strains were fully differentiated either directly or via high-resolution plots obtained by heteroduplex formation between coamplified PCR products of the tested staphylococcal strain and phylogenetically unrelated strain.

  15. Providing Internet Access to High-Resolution Mars Images

    Science.gov (United States)

    Plesea, Lucian

    2008-01-01

    The OnMars server is a computer program that provides Internet access to high-resolution Mars images, maps, and elevation data, all suitable for use in geographical information system (GIS) software for generating images, maps, and computational models of Mars. The OnMars server is an implementation of the Open Geospatial Consortium (OGC) Web Map Service (WMS) server. Unlike other Mars Internet map servers that provide Martian data using an Earth coordinate system, the OnMars WMS server supports encoding of data in Mars-specific coordinate systems. The OnMars server offers access to most of the available high-resolution Martian image and elevation data, including an 8-meter-per-pixel uncontrolled mosaic of most of the Mars Global Surveyor (MGS) Mars Observer Camera Narrow Angle (MOCNA) image collection, which is not available elsewhere. This server can generate image and map files in the tagged image file format (TIFF), Joint Photographic Experts Group (JPEG), 8- or 16-bit Portable Network Graphics (PNG), or Keyhole Markup Language (KML) format. Image control is provided by use of the OGC Style Layer Descriptor (SLD) protocol. The OnMars server also implements tiled WMS protocol and super-overlay KML for high-performance client application programs.

  16. Providing Internet Access to High-Resolution Lunar Images

    Science.gov (United States)

    Plesea, Lucian

    2008-01-01

    The OnMoon server is a computer program that provides Internet access to high-resolution Lunar images, maps, and elevation data, all suitable for use in geographical information system (GIS) software for generating images, maps, and computational models of the Moon. The OnMoon server implements the Open Geospatial Consortium (OGC) Web Map Service (WMS) server protocol and supports Moon-specific extensions. Unlike other Internet map servers that provide Lunar data using an Earth coordinate system, the OnMoon server supports encoding of data in Moon-specific coordinate systems. The OnMoon server offers access to most of the available high-resolution Lunar image and elevation data. This server can generate image and map files in the tagged image file format (TIFF) or the Joint Photographic Experts Group (JPEG), 8- or 16-bit Portable Network Graphics (PNG), or Keyhole Markup Language (KML) format. Image control is provided by use of the OGC Style Layer Descriptor (SLD) protocol. Full-precision spectral arithmetic processing is also available, by use of a custom SLD extension. This server can dynamically add shaded relief based on the Lunar elevation to any image layer. This server also implements tiled WMS protocol and super-overlay KML for high-performance client application programs.

  17. High-resolution diffraction grating interferometric transducer of linear displacements

    Science.gov (United States)

    Shang, Ping; Xia, Haojie; Fei, Yetai

    2016-01-01

    A high-resolution transducer of linear displacements is presented. The system is based on semiconductor laser illumination and a diffraction grating applied as a length master. The theory of the optical method is formulated using Doppler description. The relationship model among the interference strips, measurement errors, grating deflection around the X, Y and Z axes and translation along the Z axis is built. The grating interference strips' direction and space is not changed with movement along the X (direction of grating movement), Y (direction of grating line), Z axis, and the direction and space has a great effect when rotating around the X axis. Moreover the space is little affected by deflection around the Z axis however the direction is changed dramatically. In addition, the strips' position shifted rightward or downwards respectively for deflection around the X or Y axis. Because the emitted beams are separated on the grating plane, the tilt around the X axis error of the stage during motion will lead to the optical path difference of the two beams resulting in phase shift. This study investigates the influence of the tilt around the X axis error. Experiments show that after yaw error compensation, the high-resolution diffraction grating interferometric transducer readings can be significantly improved. The error can be reduced from +/-80 nm to +/-30 nm in maximum.

  18. High resolution multiplexed functional imaging in live embryos (Conference Presentation)

    Science.gov (United States)

    Xu, Dongli; Zhou, Weibin; Peng, Leilei

    2017-02-01

    Fourier multiplexed fluorescence lifetime imaging (FmFLIM) scanning laser optical tomography (FmFLIM-SLOT) combines FmFLIM and Scanning laser optical tomography (SLOT) to perform multiplexed 3D FLIM imaging of live embryos. The system had demonstrate multiplexed functional imaging of zebrafish embryos genetically express Foster Resonant Energy Transfer (FRET) sensors. However, previous system has a 20 micron resolution because the focused Gaussian beam diverges quickly from the focused plane, makes it difficult to achieve high resolution imaging over a long projection depth. Here, we present a high-resolution FmFLIM-SLOT system with achromatic Bessel beam, which achieves 3 micron resolution in 3D deep tissue imaging. In Bessel-FmFLIM-SLOT, multiple laser excitation lines are firstly intensity modulated by a Michelson interferometer with a spinning polygon mirror optical delay line, which enables Fourier multiplexed multi-channel lifetime measurements. Then, a spatial light modulator and a prism are used to transform the modulated Gaussian laser beam to an achromatic Bessel beam. The achromatic Bessel beam scans across the whole specimen with equal angular intervals as sample rotated. After tomography reconstruction and the frequency domain lifetime analysis method, both the 3D intensity and lifetime image of multiple excitation-emission can be obtained. Using Bessel-FmFLIM-SLOT system, we performed cellular-resolution FLIM tomography imaging of live zebrafish embryo. Genetically expressed FRET sensors in these embryo will allow non-invasive observation of multiple biochemical processes in vivo.

  19. Hyperresolution: an hyperspectral and high resolution imager for Earth observation

    Science.gov (United States)

    De Vidi, R.; Chiarantini, L.; Bini, A.

    2017-11-01

    Hyperspectral space imagery is an emerging technology that supports many scientific, civil, security and defence operational applications. The main advantage of this remote sensing technique is that it allows the so-called Feature Extraction: in fact the spectral signature allows the recognition of the materials composing the scene. Hyperspectral Products and their applications have been investigated in the past years by Galileo Avionica to direct the instrument characteristics design. Sample products have been identified in the civil / environment monitoring fields (such as coastal monitoring, vegetation, hot spot and urban classification) and in defense / security applications: their performances have been verified by means of airborne flight campaigns. The Hyperspectral and High Resolution Imager is a space-borne instrument that implement a pushbroom technique to get strip spectral images over the Hyperspectral VNIR and SWIR bands, with a ground sample distance at nadir of 20m in a 20 km wide ground swath, with 200 spectral channels, realizing an average spectral resolution of 10nm. The High Resolution Panchromatic Channel insists in the same swath to allow for multiresolution data fusion of hyperspectral imagery.

  20. Quantitative analysis of cholesteatoma using high resolution computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    Kikuchi, Shigeru; Yamasoba, Tatsuya (Kameda General Hospital, Chiba (Japan)); Iinuma, Toshitaka

    1992-05-01

    Seventy-three cases of adult cholesteatoma, including 52 cases of pars flaccida type cholesteatoma and 21 of pars tensa type cholesteatoma, were examined using high resolution computed tomography, in both axial (lateral semicircular canal plane) and coronal sections (cochlear, vestibular and antral plane). These cases were classified into two subtypes according to the presence of extension of cholesteatoma into the antrum. Sixty cases of chronic otitis media with central perforation (COM) were also examined as controls. Various locations of the middle ear cavity were measured in terms of size in comparison with pars flaccida type cholesteatoma, pars tensa type cholesteatoma and COM. The width of the attic was significantly larger in both pars flaccida type and pars tensa type cholesteatoma than in COM. With pars flaccida type cholesteatoma there was a significantly larger distance between the malleus and lateral wall of the attic than with COM. In contrast, the distance between the malleus and medial wall of the attic was significantly larger with pars tensa type cholesteatoma than with COM. With cholesteatoma extending into the antrum, regardless of the type of cholesteatoma, there were significantly larger distances than with COM at the following sites: the width and height of the aditus ad antrum, and the width, height and anterior-posterior diameter of the antrum. However, these distances were not significantly different between cholesteatoma without extension into the antrum and COM. The hitherto demonstrated qualitative impressions of bone destruction in cholesteatoma were quantitatively verified in detail using high resolution computed tomography. (author).

  1. High-resolution electron microscopy of advanced materials

    Energy Technology Data Exchange (ETDEWEB)

    Mitchell, T.E.; Kung, H.H.; Sickafus, K.E.; Gray, G.T. III; Field, R.D.; Smith, J.F. [Los Alamos National Lab., NM (United States). Materials Science and Technology Div.

    1997-11-01

    This final report chronicles a three-year, Laboratory Directed Research and Development (LDRD) project at Los Alamos National Laboratory (LANL). The High-Resolution Electron Microscopy Facility has doubled in size and tripled in quality since the beginning of the three-year period. The facility now includes a field-emission scanning electron microscope, a 100 kV field-emission scanning transmission electron microscope (FE-STEM), a 300 kV field-emission high-resolution transmission electron microscope (FE-HRTEM), and a 300 kV analytical transmission electron microscope. A new orientation imaging microscope is being installed. X-ray energy dispersive spectrometers for chemical analysis are available on all four microscopes; parallel electron energy loss spectrometers are operational on the FE-STEM and FE-HRTEM. These systems enable evaluation of local atomic bonding, as well as chemical composition in nanometer-scale regions. The FE-HRTEM has a point-to-point resolution of 1.6 {angstrom}, but the resolution can be pushed to its information limit of 1 {angstrom} by computer reconstruction of a focal series of images. HRTEM has been used to image the atomic structure of defects such as dislocations, grain boundaries, and interfaces in a variety of materials from superconductors and ferroelectrics to structural ceramics and intermetallics.

  2. High-Resolution Mars Camera Test Image of Moon (Infrared)

    Science.gov (United States)

    2005-01-01

    This crescent view of Earth's Moon in infrared wavelengths comes from a camera test by NASA's Mars Reconnaissance Orbiter spacecraft on its way to Mars. The mission's High Resolution Imaging Science Experiment camera took the image on Sept. 8, 2005, while at a distance of about 10 million kilometers (6 million miles) from the Moon. The dark feature on the right is Mare Crisium. From that distance, the Moon would appear as a star-like point of light to the unaided eye. The test verified the camera's focusing capability and provided an opportunity for calibration. The spacecraft's Context Camera and Optical Navigation Camera also performed as expected during the test. The Mars Reconnaissance Orbiter, launched on Aug. 12, 2005, is on course to reach Mars on March 10, 2006. After gradually adjusting the shape of its orbit for half a year, it will begin its primary science phase in November 2006. From the mission's planned science orbit about 300 kilometers (186 miles) above the surface of Mars, the high resolution camera will be able to discern features as small as one meter or yard across.

  3. MR-Venography Using High Resolution True-FISP

    Energy Technology Data Exchange (ETDEWEB)

    Spuentrup, E. [Technische Hochschule Aachen (Germany). Klinik fuer Radiologische Diagnostik; Beth Israel Deaconess Medical Center, Boston, MA (United States). Dept. of Medicine; Harvard Medical School, Boston, MA (United States); Buecker, A.; Guenther, R.W. [Technische Hochschule Aachen (Germany). Klinik fuer Radiologische Diagnostik; Stuber, M. [Beth Israel Deaconess Medical Center, Boston, MA (United States). Dept. of Medicine; Harvard Medical School, Boston, MA (United States); Philips Med. Syst., Best (Netherlands)

    2001-08-01

    A new fast MR-venography approach using a high resolution True-FISP imaging sequence was investigated in 20 patients suffering from 23 deep vein thromboses. Diagnosis was proven by X-ray venography, CT or ultrasound examination. The presented technique allowed for clear thrombus visualization with a high contrast to the surrounding blood pool even in calf veins. Acquisition time was less than 10 minutes for imaging the pelvis and the legs. No contrast media was needed. The presented high resolution True-FISP MR-veography is a promising non-invasive, fast MR-venography approach for detection of deep venous thrombosis. (orig.) [German] Eine neue schnelle, oertlich hochaufgeloeste MR-Phlebographietechnik mit einer axialen True-FISP Bildgebungssequenz wurde an 20 Patienten mit 23 nach-gewiesenen tiefen Beinvenenthrombosen untersucht. Die Befunde wurden mit einer konventionellen Roentgenphlebographie, einer CT oder einer Sonographie gesichert. Die vorgestellte Technik erlaubte in allen Faellen eine Thrombusdarstellung mit hohem Kontrast zum umgebenden venoesen Blut, wobei aufgrund der hohen Ortsaufloesung auch die Unterschenkelvenen beurteilt werden konnten. Die Datenaufnahmezeit zur Untersuchung des Beckens und der Beine betrug weniger als 10 Minuten. Kontrastmittel wurde nicht benoetigt. Die vorgestellte MR-Phlebographietechnik unter Verwendung einer oertlich hochauf-geloesten True-FISP Sequenz ist eine neue, vielversprechende, nicht-invasive Technik zur Diagnostik der tiefen Bein- und Beckenvenenthrombose. (orig.)

  4. High-resolution digital imaging with storage phosphors.

    Science.gov (United States)

    Fuhrman, C R; Gur, D; Schaetzing, R

    1990-01-01

    This article describes the current status and potential applications of high-resolution storage phosphor for imaging of the chest. Digital imaging that uses storage phosphor technology is easily adaptable to existing x-ray--generating equipment and can also be used with mobile equipment. The wide latitude of the storage phosphor technique permits satisfactory imaging in situations in which exposure factors cannot be accurately estimated or easily controlled. Early experience with an experimental Kodak high-resolution (4K x 4K) storage phosphor system suggests that standard and portal chest images of excellent quality can be obtained. Many issues must be resolved, however, before digital radiology with a storage phosphor can be advocated as being preferable to conventional film-screen systems. These issues, which include display modalities (film or television monitor), resolution requirements, and the effects of image processing, can only be resolved by further large-scale accuracy studies. The change to a digital imaging system will involve major expenditures for equipment and computers. Cost will be related largely to the level of spatial resolution required for primary radiographic diagnosis.

  5. High resolution neutron diffractometer HRND at research reactor CMRR

    Science.gov (United States)

    Zhang, J.; Xia, Y.; Wang, Y.; Xie, C.; Sun, G.; Liu, L.; Pang, B.; Li, J.; Huang, C.; Liu, Y.; Gong, J.

    2018-01-01

    The high resolution neutron diffractometer HRND is located at the 20 MW China Mianyang Research Reactor (CMRR), which is a neutron powder diffractometer especially dedicated to crystal and magnetic structure studies for polycrystalline powder samples. A vertical focusing Ge (511) monochromator produce a monochromatic neutron beam with a wavelength of 1.885 Å at a fixed take-off angle of 120o. An array of 64 equidistant 3He filled proportional counters can acquire diffraction patterns with a large-scale diffraction angle range over 160o. As all the Soller slit collimators of HRND have a collimation angle of 10' and the monochromator has an average mosaicity of 0.359o, HRND obtains a best resolution of about 1.6\\textperthousand based on experiments, which makes the resolution of HRND can compete with the mainstream-level high resolution neutron powder diffractometers in the world. Equipped with a cryostat and a furnace, HRND allows structural characterization in an extremely broad temperature range. The details of the configuration and performance of the instrument are reported along with its specifications and performance assessments in the present paper.

  6. Characterization of ceramic archaeological by high resolution X ray microtomography

    Energy Technology Data Exchange (ETDEWEB)

    Machado, Alessandra C.; Freitas, Renato; Calza, Cristiane F.; Lopes, Ricardo T.; Lima, Inaya, E-mail: alecastro@lin.ufrj.br [Coordenacao dos Programas de Pos-Graduacao de Engenharia (COPPE/UFRJ), Rio de Janeiro, RJ (Brazil). Lab. de Instrumentacao Nuclear; Carvalho, Daniele D.; Gaspar, Maria D. [Museu Nacional (MN/UFRJ), RJ (Brazil). Centro de Tecnologia

    2013-07-01

    Characterization of ceramic fragments is a very important area of research in art and archeometry area because it enables a greater understanding of how ancient civilizations behave and what were their traditions and customs. Petrography and chemical analyses are commonly used, but these techniques are destructive, which is not interesting for this type of sample. Through the exchange of multidisciplinary scientific knowledge and new partnerships, high resolution X-ray microtomography has been introduced in archaeological area as a great possibility of 3D inspection in a non-destructive way. The goal of this work is to investigate the internal microstructures of four samples of archeological ceramic, from the Archaeological Site of Macacu - RJ. The X-ray microtomography were performed in a high resolution setup, and can be used to infer the nature of organic temper even with all plant remains completely burnt out during the firing process and also to ensure the homogeneity of samples envisaged for geochemical analyses, especially with respect to the distribution of chemically diverse fabric compounds. In this way this study intends to contribute to our understanding of the archaeological and historical formations of this region. (author)

  7. Segmentation of Striatal Brain Structures from High Resolution PET Images

    Directory of Open Access Journals (Sweden)

    Ricardo J. P. C. Farinha

    2009-01-01

    Full Text Available We propose and evaluate an automatic segmentation method for extracting striatal brain structures (caudate, putamen, and ventral striatum from parametric C11-raclopride positron emission tomography (PET brain images. We focus on the images acquired using a novel brain dedicated high-resolution (HRRT PET scanner. The segmentation method first extracts the striatum using a deformable surface model and then divides the striatum into its substructures based on a graph partitioning algorithm. The weighted kernel k-means algorithm is used to partition the graph describing the voxel affinities within the striatum into the desired number of clusters. The method was experimentally validated with synthetic and real image data. The experiments showed that our method was able to automatically extract caudate, ventral striatum, and putamen from the images. Moreover, the putamen could be subdivided into anterior and posterior parts. An automatic method for the extraction of striatal structures from high-resolution PET images allows for inexpensive and reproducible extraction of the quantitative information from these images necessary in brain research and drug development.

  8. Wavelength Converters

    DEFF Research Database (Denmark)

    Kloch, Allan; Hansen, Peter Bukhave; Wolfson, David

    1999-01-01

    . It is predicted that jitter accumulation can be minimised by using a 9-10 dB ratio between the signal and CW power also assuring a high extinction ratio. Using this guideline simulations show that 20 cross-gain modulation converters can be cascaded at 10 Gbit/s with only ~20 ps of accumulated jitter...... and an extinction ratio of ~10 dB.The regenerative capabilities of the cross-phase converters are described and verified experimentally at 20 Gbit/s, where the noise redistribution and improvement of the signal-to-noise ratio clearly is demonstrated by controlling the input power to an EDFA. In a similar experiment...... at 2.5 Gbit/s, the regeneration causes a reduction of the required input power to an in-line EDFA of ~6 dB for a power penalty of 1 dB at a bit error rate of 10-9. If two converters are concatenated the power requirement is reduced ~8 dB. Obviously, the power reduction allows for longer spans between...

  9. High resolution infrared acquisitions droning over the LUSI mud eruption.

    Science.gov (United States)

    Di Felice, Fabio; Romeo, Giovanni; Di Stefano, Giuseppe; Mazzini, Adriano

    2016-04-01

    The use of low-cost hand-held infrared (IR) thermal cameras based on uncooled micro-bolometer detector arrays became more widespread during the recent years. Thermal cameras have the ability to estimate temperature values without contact and therefore can be used in circumstances where objects are difficult or dangerous to reach such as volcanic eruptions. Since May 2006 the Indonesian LUSI mud eruption continues to spew boiling mud, water, aqueous vapor, CO2, CH4 and covers a surface of nearly 7 km2. At this locality we performed surveys over the unreachable erupting crater. In the framework of the LUSI Lab project (ERC grant n° 308126), in 2014 and 2015, we acquired high resolution infrared images using a specifically equipped remote-controlled drone flying at an altitude of m 100. The drone is equipped with GPS and an autopilot system that allows pre-programming the flying path or designing grids. The mounted thermal camera has peak spectral sensitivity in LW wavelength (μm 10) that is characterized by low water vapor and CO2 absorption. The low distance (high resolution) acquisitions have a temperature detail every cm 40, therefore it is possible to detect and observe physical phenomena such as thermodynamic behavior, hot mud and fluids emissions locations and their time shifts. Despite the harsh logistics and the continuously varying gas concentrations we managed to collect thermal images to estimate the crater zone spatial thermal variations. We applied atmosphere corrections to calculate infrared absorption by high concentration of water vapor. Thousands of images have been stitched together to obtain a mosaic of the crater zone. Regular monitoring with heat variation measurements collected, e.g. every six months, could give important information about the volcano activity estimating its evolution. A future data base of infrared high resolution and visible images stored in a web server could be a useful monitoring tool. An interesting development will be

  10. High resolution remote sensing of water surface patterns

    Science.gov (United States)

    Woodget, A.; Visser, F.; Maddock, I.; Carbonneau, P.

    2012-12-01

    The assessment of in-stream habitat availability within fluvial environments in the UK traditionally includes the mapping of patterns which appear on the surface of the water, known as 'surface flow types' (SFTs). The UK's River Habitat Survey identifies ten key SFTs, including categories such as rippled flow, upwelling, broken standing waves and smooth flow. SFTs result from the interaction between the underlying channel morphology, water depth and velocity and reflect the local flow hydraulics. It has been shown that SFTs can be both biologically and hydraulically distinct. SFT mapping is usually conducted from the river banks where estimates of spatial coverage are made by eye. This approach is affected by user subjectivity and inaccuracies in the spatial extent of mapped units. Remote sensing and specifically the recent developments in unmanned aerial systems (UAS) may now offer an alternative approach for SFT mapping, with the capability for rapid and repeatable collection of very high resolution imagery from low altitudes, under bespoke flight conditions. This PhD research is aimed at investigating the mapping of SFTs using high resolution optical imagery (less than 10cm) collected from a helicopter-based UAS flown at low altitudes (less than 100m). This paper presents the initial findings from a series of structured experiments on the River Arrow, a small lowland river in Warwickshire, UK. These experiments investigate the potential for mapping SFTs from still and video imagery of different spatial resolutions collected at different flying altitudes and from different viewing angles (i.e. vertical and oblique). Imagery is processed using 3D mosaicking software to create orthophotos and digital elevation models (DEM). The types of image analysis which are tested include a simple, manual visual assessment undertaken in a GIS environment, based on the high resolution optical imagery. In addition, an object-based image analysis approach which makes use of the

  11. A PICTORIAL PRESENTATION OF ESOPHAGEAL HIGH RESOLUTION MANOMETRY CURRENT PARAMETERS.

    Science.gov (United States)

    Lafraia, Fernanda M; Herbella, Fernando A M; Kalluf, Julia R; Patti, Marco G

    2017-01-01

    High resolution manometry is the current technology used to the study of esophageal motility and is replacing conventional manometry in important centers for esophageal motility with parameters used on esophageal motility, following the Chicago Classification. This classification unifies high resolution manometry interpretation and classifies esophageal disorders. This review shows, in a pictorial presentation, the new parameters established by the Chicago Classification, version 3.0, aimed to allow an easy comprehension and interpretation of high resolution manometry. Esophageal manometries performed by the authors were reviewed to select illustrative tracings representing Chicago Classification parameters. The parameters are: Esophagogastric Morphology, that classifies this junction according to its physiology and anatomy; Integrated Relaxation Pressure, that measures the lower esophageal sphincter relaxation; Distal Contractile Integral, that evaluates the contraction vigor of each wave; and, Distal Latency, that measures the peristalsis velocity from the beginning of the swallow to the epiphrenic ampulla. Clinical applications of these new concepts is still under evaluation. Mostrar, de forma pictórica, os novos parâmetros compilados na versão 3.0 da Classificação de Chicago, buscando facilitar a compreensão e interpretação da manometria de alta resolução. Foram revistas as manometrias da casuística dos autores e selecionados os traçados representativos dos parâmetros da Classificação de Chicago. Entre os parâmetros apresentados foram considerados a Morfologia da Transição Gastroesofágica, que classifica o segmento de acordo com sua fisiologia e anatomia; a Integral da Pressão de Relaxamento, que mede o relaxamento do esfíncter esofagiano inferior; a Integral Contrátil Distal, que avalia o vigor contrátil da onda peristáltica; e, a Latência Distal, que mede o tempo da peristalse, desde o início da deglutição até a ampola epifr

  12. Optical Histology: High-Resolution Visualization of Tissue Microvasculature

    Science.gov (United States)

    Moy, Austin Jing-Ming

    Mammalian tissue requires the delivery of nutrients, growth factors, and the exchange of oxygen and carbon dioxide gases to maintain normal function. These elements are delivered by the blood, which travels through the connected network of blood vessels, known as the vascular system. The vascular system consists of large feeder blood vessels (arteries and veins) that are connected to the small blood vessels (arterioles and venules), which in turn are connected to the capillaries that are directly connected to the tissue and facilitate gas exchange and nutrient delivery. These small blood vessels and capillaries make up an intricate but organized network of blood vessels that exist in all mammalian tissues known as the microvasculature and are very important in maintaining the health and proper function of mammalian tissue. Due to the importance of the microvasculature in tissue survival, disruption of the microvasculature typically leads to tissue dysfunction and tissue death. The most prevalent method to study the microvasculature is visualization. Immunohistochemistry (IHC) is the gold-standard method to visualize tissue microvasculature. IHC is very well-suited for highly detailed interrogation of the tissue microvasculature at the cellular level but is unwieldy and impractical for wide-field visualization of the tissue microvasculature. The objective my dissertation research was to develop a method to enable wide-field visualization of the microvasculature, while still retaining the high-resolution afforded by optical microscopy. My efforts led to the development of a technique dubbed "optical histology" that combines chemical and optical methods to enable high-resolution visualization of the microvasculature. The development of the technique first involved preliminary studies to quantify optical property changes in optically cleared tissues, followed by development and demonstration of the methodology. Using optical histology, I successfully obtained high

  13. High resolution modelling of extreme precipitation events in urban areas

    Science.gov (United States)

    Siemerink, Martijn; Volp, Nicolette; Schuurmans, Wytze; Deckers, Dave

    2015-04-01

    The present day society needs to adjust to the effects of climate change. More extreme weather conditions are expected, which can lead to longer periods of drought, but also to more extreme precipitation events. Urban water systems are not designed for such extreme events. Most sewer systems are not able to drain the excessive storm water, causing urban flooding. This leads to high economic damage. In order to take appropriate measures against extreme urban storms, detailed knowledge about the behaviour of the urban water system above and below the streets is required. To investigate the behaviour of urban water systems during extreme precipitation events new assessment tools are necessary. These tools should provide a detailed and integral description of the flow in the full domain of overland runoff, sewer flow, surface water flow and groundwater flow. We developed a new assessment tool, called 3Di, which provides detailed insight in the urban water system. This tool is based on a new numerical methodology that can accurately deal with the interaction between overland runoff, sewer flow and surface water flow. A one-dimensional model for the sewer system and open channel flow is fully coupled to a two-dimensional depth-averaged model that simulates the overland flow. The tool uses a subgrid-based approach in order to take high resolution information of the sewer system and of the terrain into account [1, 2]. The combination of using the high resolution information and the subgrid based approach results in an accurate and efficient modelling tool. It is now possible to simulate entire urban water systems using extreme high resolution (0.5m x 0.5m) terrain data in combination with a detailed sewer and surface water network representation. The new tool has been tested in several Dutch cities, such as Rotterdam, Amsterdam and The Hague. We will present the results of an extreme precipitation event in the city of Schiedam (The Netherlands). This city deals with

  14. Do high-resolution convection-permitting experiments on Europe need to be driven by high resolution global runs?

    Science.gov (United States)

    Berthou, Segolene; Chan, Steven; Kendon, Elizabeth; Roberts, Malcolm; Lee, Robert; Vanniere, Benoit

    2017-04-01

    Challenges of getting appropriate climate-change scenarios over Europe both come from having a good representation of the synoptic systems reaching Europe and having a good-enough representation of local and orographic processes in Europe. Therefore we perform both the evaluation of the driving global model and its dynamical downscaling with a 2.2km regional model on the present day period, in the perspective of using this configuration in a future climate scenario. 20-year long atmosphere-only simulations with the Unified Model of the Met Office were run at different global resolutions (130km, 60km and 25km) and the highest resolution was chosen to give the boundaries of a European-wide convection permitting simulation with a 2.2km resolution. The synoptic situation of the different global resolutions are comparable in terms of latitudinal distribution of the jets and weather regimes but there is consistent improvement in the frequency of storms reaching Europe at 25km resolution. High resolution global runs therefore mainly show added value in the high-frequency synoptic drivers. Compared to high resolution precipitation datasets, the 25km resolution is showing good representation of winter precipitation distribution, although with too many days of moderate precipitation in Western Europe. It shows a dry bias in summer, consistent with a mean jet too north.

  15. Quantitative high-resolution transmission electron microscopy of single atoms.

    Science.gov (United States)

    Gamm, Björn; Blank, Holger; Popescu, Radian; Schneider, Reinhard; Beyer, André; Gölzhäuser, Armin; Gerthsen, Dagmar

    2012-02-01

    Single atoms can be considered as the most basic objects for electron microscopy to test the microscope performance and basic concepts for modeling image contrast. In this work high-resolution transmission electron microscopy was applied to image single platinum, molybdenum, and titanium atoms in an aberration-corrected transmission electron microscope. The atoms are deposited on a self-assembled monolayer substrate that induces only negligible contrast. Single-atom contrast simulations were performed on the basis of Weickenmeier-Kohl and Doyle-Turner form factors. Experimental and simulated image intensities are in quantitative agreement on an absolute intensity scale, which is provided by the vacuum image intensity. This demonstrates that direct testing of basic properties such as form factors becomes feasible.

  16. High-Resolution Transmission Electron Microscopy - and Associated Techniques

    Science.gov (United States)

    Buseck, Peter; Cowley, John; Eyring, Leroy

    1989-02-01

    This book provides an introduction to the fundamental concepts, techniques, and methods used for electron microscopy at high resolution in space, energy, and even in time. It delineates the theory of elastic scattering, which is most useful for spectroscopic and chemical analyses. There are also discussions of the theory and practice of image calculations, and applications of HRTEM to the study of solid surfaces, highly disordered materials, solid state chemistry, mineralogy, semiconductors and metals. Contributors include J. Cowley, J. Spence, P. Buseck, P. Self, and M.A. O'Keefe. Compiled by experts in the fields of geology, physics and chemistry, this comprehensive text will be the standard reference for years to come.

  17. High-resolution imaging methods in array signal processing

    DEFF Research Database (Denmark)

    Xenaki, Angeliki

    The purpose of this study is to develop methods in array signal processing which achieve accurate signal reconstruction from limited observations resulting in high-resolution imaging. The focus is on underwater acoustic applications and sonar signal processing both in active (transmit and receive...... in active sonar signal processing for detection and imaging of submerged oil contamination in sea water from a deep-water oil leak. The submerged oil _eld is modeled as a uid medium exhibiting spatial perturbations in the acoustic parameters from their mean ambient values which cause weak scattering......-of-arrival (DOA) of the associated wavefronts from a limited number of observations. Usually, there are only a few sources generating the acoustic wavefield such that DOA estimation is essentially a sparse signal reconstruction problem. Conventional methods for DOA estimation (i.e., beamforming) suffer from...

  18. Sparse Representation Denoising for Radar High Resolution Range Profiling

    Directory of Open Access Journals (Sweden)

    Min Li

    2014-01-01

    Full Text Available Radar high resolution range profile has attracted considerable attention in radar automatic target recognition. In practice, radar return is usually contaminated by noise, which results in profile distortion and recognition performance degradation. To deal with this problem, in this paper, a novel denoising method based on sparse representation is proposed to remove the Gaussian white additive noise. The return is sparsely described in the Fourier redundant dictionary and the denoising problem is described as a sparse representation model. Noise level of the return, which is crucial to the denoising performance but often unknown, is estimated by performing subspace method on the sliding subsequence correlation matrix. Sliding window process enables noise level estimation using only one observation sequence, not only guaranteeing estimation efficiency but also avoiding the influence of profile time-shift sensitivity. Experimental results show that the proposed method can effectively improve the signal-to-noise ratio of the return, leading to a high-quality profile.

  19. Object-Based Building Extraction from High Resolution Satellite Imagery

    Directory of Open Access Journals (Sweden)

    R. Attarzadeh

    2012-07-01

    Full Text Available Automatic building extraction from high resolution satellite imagery is considered as an important field of research in remote sensing and machine vision. Many algorithms for extraction of buildings from satellite images have been presented so far. These algorithms mainly have considered radiometric, geometric, edge detection and shadow criteria approaches to perform the building extraction. In this paper, we propose a novel object based approach for automatic and robust detection and extraction of building in high spatial resolution images. To achieve this goal, we use stable and variable features together. Stable features are derived from inherent characteristics of building phenomenon and variable features are extracted using SEparability and THresholds analysis tool. The proposed method has been applied on a QuickBird imagery of an urban area in Isfahan city and visual validation demonstrates that the proposed method provides promising results.

  20. High-Resolution Data for a Low-Resolution World

    Energy Technology Data Exchange (ETDEWEB)

    Brady, Brendan Williams [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-05-10

    In the past 15 years, the upper section of Cañon de Valle has been severely altered by wildfires and subsequent runoff events. Loss of root structures on high-angle slopes results in debris flow and sediment accumulation in the narrow canyon bottom. The original intent of the study described here was to better understand the changes occurring in watershed soil elevations over the course of several post-fire years. An elevation dataset from 5 years post-Cerro Grande fire was compared to high-resolution LiDAR data from 14 years post-Cerro Grande fire (also 3 years post-Las Conchas fire). The following analysis was motivated by a problematic comparison of these datasets of unlike resolution, and therefore focuses on what the data reveals of itself. The objective of this study is to highlight the effects vegetation can have on remote sensing data that intends to read ground surface elevation.

  1. Localized corrosion information using high resolution measurement devices

    DEFF Research Database (Denmark)

    Ambat, Rajan

    2005-01-01

    High performance demand for several engineering alloys and components, and miniaturization of electronics and development of MEMS requires better understanding of local corrosion characteristics frequently down to µm scale. This is because in metallic materials corrosion is a sensitive function...... in conjunction with microstructural analysis, using advanced microscopic tools, becomes very important. Corrosion of microelectronics circuits and MEMs is also a recent problem, which demands measurement resolution down to few microns as the components are extremely small, and measurement needs to be carried out...... of the technique could be further enhanced by adding new features such as high resolution video visualization systems, fretting/tribo-corroson attachments, and also by integrating it with stress corrosion testing, corrosion investigation of concrete for a few to name with. The corrosion group in MPT, Technical...

  2. High-Resolution Characterization of UMo Alloy Microstructure

    Energy Technology Data Exchange (ETDEWEB)

    Devaraj, Arun [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Kovarik, Libor [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Joshi, Vineet V. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Jana, Saumyadeep [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Manandhar, Sandeep [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Arey, Bruce W. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Lavender, Curt A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-11-30

    This report highlights the capabilities and procedure for high-resolution characterization of UMo fuels in PNNL. Uranium-molybdenum (UMo) fuel processing steps, from casting to forming final fuel, directly affect the microstructure of the fuel, which in turn dictates the in-reactor performance of the fuel under irradiation. In order to understand the influence of processing on UMo microstructure, microstructure characterization techniques are necessary. Higher-resolution characterization techniques like transmission electron microscopy (TEM) and atom probe tomography (APT) are needed to interrogate the details of the microstructure. The findings from TEM and APT are also directly beneficial for developing predictive multiscale modeling tools that can predict the microstructure as a function of process parameters. This report provides background on focused-ion-beam–based TEM and APT sample preparation, TEM and APT analysis procedures, and the unique information achievable through such advanced characterization capabilities for UMo fuels, from a fuel fabrication capability viewpoint.

  3. High resolution capacitance detection circuit for rotor micro-gyroscope

    Directory of Open Access Journals (Sweden)

    Ming-Yuan Ren

    2014-03-01

    Full Text Available Conventional methods for rotor position detection of micro-gyroscopes include common exciting electrodes (single frequency and common sensing electrodes (frequency multiplex, but they have encountered some problems. So we present a high resolution and low noise pick-off circuit for micro-gyroscopes which utilizes the time multiplex method. The detecting circuit adopts a continuous-time current sensing circuit for capacitance measurement, and its noise analysis of the charge amplifier is introduced. The equivalent output noise power spectral density of phase-sensitive demodulation is 120 nV/Hz1/2. Tests revealed that the whole circuitry has a relative capacitance resolution of 1 × 10−8.

  4. High-resolution structure of viruses from random diffraction snapshots

    CERN Document Server

    Hosseinizadeh, A; Dashti, A; Fung, R; D'Souza, R M; Ourmazd, A

    2014-01-01

    The advent of the X-ray Free Electron Laser (XFEL) has made it possible to record diffraction snapshots of biological entities injected into the X-ray beam before the onset of radiation damage. Algorithmic means must then be used to determine the snapshot orientations and thence the three-dimensional structure of the object. Existing Bayesian approaches are limited in reconstruction resolution typically to 1/10 of the object diameter, with the computational expense increasing as the eighth power of the ratio of diameter to resolution. We present an approach capable of exploiting object symmetries to recover three-dimensional structure to high resolution, and thus reconstruct the structure of the satellite tobacco necrosis virus to atomic level. Our approach offers the highest reconstruction resolution for XFEL snapshots to date, and provides a potentially powerful alternative route for analysis of data from crystalline and nanocrystalline objects.

  5. Study of CME Properties Using High Resolution Data

    Science.gov (United States)

    Egorov, Ya. I.; Fainshtein, V. G.

    The joint use of high-resolution data from SDO and PROBA2 satellites and LASCO/SOHO coronographs enabled us to examine early stages of initiation and propagation of six limb CMEs registered in June 2010 - June 2011. For five events under consideration, the CME initiation is marked by filament (prominence) eruption or by a loop-like structure having another nature. Subsequently, several loop-like structures having higher brightness and following each other at different velocities appear in the region of the CME initiation. The CME frontal structure is formed by these loop-like structures. The CME kinematics and such CME characteristics as angular size and longitudinal to latitudinal size ratio was found for considered all events. We have drawn a conclusion about the possible existence of two CME types dependent on the velocity profile.

  6. High-Resolution Mammography Detector Employing Optical Switching Readout

    Science.gov (United States)

    Irisawa, Kaku; Kaneko, Yasuhisa; Yamane, Katsutoshi; Sendai, Tomonari; Hosoi, Yuichi

    Conceiving a new detector structure, FUJIFILM Corporation has successfully put its invention of an X-ray detector employing "Optical Switching" into practical use. Since Optical Switching Technology allows an electrode structure to be easily designed, both high resolution of pixel pitch and low electrical noise readout have been achieved, which have consequently realized the world's smallest pixel size of 50×50 μm2 from a Direct-conversion FPD system as well as high DQE. The digital mammography system equipped with this detector enables to acquire high definition images while maintaining granularity. Its outstanding feature is to be able to acquire high-precision images of microcalcifications which is an important index in breast examination.

  7. Optical diffraction tomography for high resolution live cell imaging

    Science.gov (United States)

    Sung, Yongjin; Choi, Wonshik; Fang-Yen, Christopher; Badizadegan, Kamran; Dasari, Ramachandra R.; Feld, Michael S.

    2009-01-01

    We report the experimental implementation of optical diffraction tomography for quantitative 3D mapping of refractive index in live biological cells. Using a heterodyne Mach-Zehnder interferometer, we record complex field images of light transmitted through a sample with varying directions of illumination. To quantitatively reconstruct the 3D map of complex refractive index in live cells, we apply optical diffraction tomography based on the Rytov approximation. In this way, the effect of diffraction is taken into account in the reconstruction process and diffraction-free high resolution 3D images are obtained throughout the entire sample volume. The quantitative refractive index map can potentially serve as an intrinsic assay to provide the molecular concentrations without the addition of exogenous agents and also to provide a method for studying the light scattering properties of single cells. PMID:19129896

  8. DMD based digital speckle illumination for high resolution imaging

    Science.gov (United States)

    Shinde, Anant; Mishra, Ayush; Perinchery, Sandeep M.; Murukeshan, V. M.

    2017-06-01

    Spatially non-uniform illumination patterns have shown significant potential to improve the imaging. Recent developments in the patterned illumination microscopy have demonstrated that the use of an optical speckle as an illumination pattern significantly improves the imaging resolution at the same time reducing the computational overheads. We present a DMD based method for generation of digital speckle pattern. The generated digital speckle and uniform white light illumination are used as two illuminations to acquire images. The image reconstruction algorithm for blind structured illumination microscopy is used to get the high resolution image. Our approach does not require any calibration step or stringent control of the illumination, and dramatically simplifies the experimental set-up.

  9. High-resolution, single-molecule measurements of biomolecular motion.

    Science.gov (United States)

    Greenleaf, William J; Woodside, Michael T; Block, Steven M

    2007-01-01

    Many biologically important macromolecules undergo motions that are essential to their function. Biophysical techniques can now resolve the motions of single molecules down to the nanometer scale or even below, providing new insights into the mechanisms that drive molecular movements. This review outlines the principal approaches that have been used for high-resolution measurements of single-molecule motion, including centroid tracking, fluorescence resonance energy transfer, magnetic tweezers, atomic force microscopy, and optical traps. For each technique, the principles of operation are outlined, the capabilities and typical applications are examined, and various practical issues for implementation are considered. Extensions to these methods are also discussed, with an eye toward future application to outstanding biological problems.

  10. Compact and mobile high resolution PET brain imager

    Science.gov (United States)

    Majewski, Stanislaw [Yorktown, VA; Proffitt, James [Newport News, VA

    2011-02-08

    A brain imager includes a compact ring-like static PET imager mounted in a helmet-like structure. When attached to a patient's head, the helmet-like brain imager maintains the relative head-to-imager geometry fixed through the whole imaging procedure. The brain imaging helmet contains radiation sensors and minimal front-end electronics. A flexible mechanical suspension/harness system supports the weight of the helmet thereby allowing for patient to have limited movements of the head during imaging scans. The compact ring-like PET imager enables very high resolution imaging of neurological brain functions, cancer, and effects of trauma using a rather simple mobile scanner with limited space needs for use and storage.

  11. Achieving High Resolution Timer Events in Virtualized Environment.

    Directory of Open Access Journals (Sweden)

    Blazej Adamczyk

    Full Text Available Virtual Machine Monitors (VMM have become popular in different application areas. Some applications may require to generate the timer events with high resolution and precision. This however may be challenging due to the complexity of VMMs. In this paper we focus on the timer functionality provided by five different VMMs-Xen, KVM, Qemu, VirtualBox and VMWare. Firstly, we evaluate resolutions and precisions of their timer events. Apparently, provided resolutions and precisions are far too low for some applications (e.g. networking applications with the quality of service. Then, using Xen virtualization we demonstrate the improved timer design that greatly enhances both the resolution and precision of achieved timer events.

  12. High resolution imaging of tunnels by magnetic resonance neurography

    Energy Technology Data Exchange (ETDEWEB)

    Subhawong, Ty K.; Thawait, Shrey K.; Machado, Antonio J.; Carrino, John A.; Chhabra, Avneesh [Johns Hopkins Hospital, The Russell H. Morgan Department of Radiology and Radiological Science, Baltimore, MD (United States); Wang, Kenneth C. [Baltimore VA Medical Center, Department of Radiology, Baltimore, MD (United States); Williams, Eric H. [Dellon Institute for Peripheral Nerve Surgery, Towson, MD (United States); Hashemi, Shahreyar Shar [Johns Hopkins Hospital, Division of Plastic and Reconstructive Surgery, Baltimore, MD (United States)

    2012-01-15

    Peripheral nerves often traverse confined fibro-osseous and fibro-muscular tunnels in the extremities, where they are particularly vulnerable to entrapment and compressive neuropathy. This gives rise to various tunnel syndromes, characterized by distinct patterns of muscular weakness and sensory deficits. This article focuses on several upper and lower extremity tunnels, in which direct visualization of the normal and abnormal nerve in question is possible with high resolution 3T MR neurography (MRN). MRN can also serve as a useful adjunct to clinical and electrophysiologic exams by discriminating adhesive lesions (perineural scar) from compressive lesions (such as tumor, ganglion, hypertrophic callous, or anomalous muscles) responsible for symptoms, thereby guiding appropriate treatment. (orig.)

  13. High Resolution Software Defined Radar System for Target Detection

    Directory of Open Access Journals (Sweden)

    S. Costanzo

    2013-01-01

    Full Text Available The Universal Software Radio Peripheral USRP NI2920, a software defined transceiver so far mainly used in Software Defined Radio applications, is adopted in this work to design a high resolution L-Band Software Defined Radar system. The enhanced available bandwidth, due to the Gigabit Ethernet interface, is exploited to obtain a higher slant-range resolution with respect to the existing Software Defined Radar implementations. A specific LabVIEW application, performing radar operations, is discussed, and successful validations are presented to demonstrate the accurate target detection capability of the proposed software radar architecture. In particular, outdoor and indoor test are performed by adopting a metal plate as reference structure located at different distances from the designed radar system, and results obtained from the measured echo are successfully processed to accurately reveal the correct target position, with the predicted slant-range resolution equal to 6 m.

  14. High-resolution 3-T MR neurography of peroneal neuropathy

    Energy Technology Data Exchange (ETDEWEB)

    Chhabra, Avneesh; Faridian-Aragh, Neda; Chalian, Majid; Soldatos, Theodoros; Thawait, Shrey K. [Johns Hopkins Hospital, The Russell H. Morgan Department of Radiology and Radiological Science, Baltimore, MD (United States); Williams, Eric H. [Johns Hopkins Hospital, Department of Plastic Surgery, Baltimore, MD (United States); Dellon Institute for Peripheral Nerve Surgery, Baltimore, MD (United States); Andreisek, Gustav [University Hospital Zurich, Institute for Diagnostic Radiology, Department of Medical Radiology, Zurich (Switzerland)

    2012-03-15

    The common peroneal nerve (CPN), a major terminal branch of the sciatic nerve, can be subject to a variety of pathologies, which may affect the nerve at any level from the lumbar plexus to its distal branches. Although the diagnosis of peripheral neuropathy is traditionally based on a patient's clinical findings and electrodiagnostic tests, magnetic resonance neurography (MRN) is gaining an increasing role in the definition of the type, site, and extent of peripheral nerve disorders. Current high-field MR scanners enable high-resolution and excellent soft-tissue contrast imaging of peripheral nerves. In the lower extremities, MR neurography has been employed in the demonstration of the anatomy and pathology of the CPN, as well as in the detection of associated secondary muscle denervation changes. This article reviews the normal appearance of the CPN as well as typical pathologies and abnormal findings at 3.0-T MR neurography of the lower extremity. (orig.)

  15. High-resolution mapping of bifurcations in nonlinear biochemical circuits

    Science.gov (United States)

    Genot, A. J.; Baccouche, A.; Sieskind, R.; Aubert-Kato, N.; Bredeche, N.; Bartolo, J. F.; Taly, V.; Fujii, T.; Rondelez, Y.

    2016-08-01

    Analog molecular circuits can exploit the nonlinear nature of biochemical reaction networks to compute low-precision outputs with fewer resources than digital circuits. This analog computation is similar to that employed by gene-regulation networks. Although digital systems have a tractable link between structure and function, the nonlinear and continuous nature of analog circuits yields an intricate functional landscape, which makes their design counter-intuitive, their characterization laborious and their analysis delicate. Here, using droplet-based microfluidics, we map with high resolution and dimensionality the bifurcation diagrams of two synthetic, out-of-equilibrium and nonlinear programs: a bistable DNA switch and a predator-prey DNA oscillator. The diagrams delineate where function is optimal, dynamics bifurcates and models fail. Inverse problem solving on these large-scale data sets indicates interference from enzymatic coupling. Additionally, data mining exposes the presence of rare, stochastically bursting oscillators near deterministic bifurcations.

  16. High Resolution Mass Spectrometry of Polyfluorinated Polyether-Based Formulation

    DEFF Research Database (Denmark)

    Dimzon, Ian Ken; Trier, Xenia; Frömel, Tobias

    2016-01-01

    High resolution mass spectrometry (HRMS) was successfully applied to elucidate the structure of a polyfluorinated polyether (PFPE)-based formulation. The mass spectrum generated from direct injection into the MS was examined by identifying the different repeating units manually and with the aid...... per molecule. The three major repeating units were -C2H4O-, -C2F4O-, and -CF2O-. Tandem MS was used to identify the end groups that appeared to be phosphates, as well as the possible distribution of the repeating units. Reversed-phase HPLC separated of the polymer molecules on the basis of number......-fluorinated polymers. The information from MS is essential in studying the physico-chemical properties of PFPEs and can help in assessing the risks they pose to the environment and to human health. Graphical Abstract ᅟ....

  17. Measuring large-scale social networks with high resolution.

    Science.gov (United States)

    Stopczynski, Arkadiusz; Sekara, Vedran; Sapiezynski, Piotr; Cuttone, Andrea; Madsen, Mette My; Larsen, Jakob Eg; Lehmann, Sune

    2014-01-01

    This paper describes the deployment of a large-scale study designed to measure human interactions across a variety of communication channels, with high temporal resolution and spanning multiple years-the Copenhagen Networks Study. Specifically, we collect data on face-to-face interactions, telecommunication, social networks, location, and background information (personality, demographics, health, politics) for a densely connected population of 1000 individuals, using state-of-the-art smartphones as social sensors. Here we provide an overview of the related work and describe the motivation and research agenda driving the study. Additionally, the paper details the data-types measured, and the technical infrastructure in terms of both backend and phone software, as well as an outline of the deployment procedures. We document the participant privacy procedures and their underlying principles. The paper is concluded with early results from data analysis, illustrating the importance of multi-channel high-resolution approach to data collection.

  18. Measuring large-scale social networks with high resolution.

    Directory of Open Access Journals (Sweden)

    Arkadiusz Stopczynski

    Full Text Available This paper describes the deployment of a large-scale study designed to measure human interactions across a variety of communication channels, with high temporal resolution and spanning multiple years-the Copenhagen Networks Study. Specifically, we collect data on face-to-face interactions, telecommunication, social networks, location, and background information (personality, demographics, health, politics for a densely connected population of 1000 individuals, using state-of-the-art smartphones as social sensors. Here we provide an overview of the related work and describe the motivation and research agenda driving the study. Additionally, the paper details the data-types measured, and the technical infrastructure in terms of both backend and phone software, as well as an outline of the deployment procedures. We document the participant privacy procedures and their underlying principles. The paper is concluded with early results from data analysis, illustrating the importance of multi-channel high-resolution approach to data collection.

  19. High resolution wind turbine wake measurements with a scanning lidar

    Science.gov (United States)

    Herges, T. G.; Maniaci, D. C.; Naughton, B. T.; Mikkelsen, T.; Sjöholm, M.

    2017-05-01

    High-resolution lidar wake measurements are part of an ongoing field campaign being conducted at the Scaled Wind Farm Technology facility by Sandia National Laboratories and the National Renewable Energy Laboratory using a customized scanning lidar from the Technical University of Denmark. One of the primary objectives is to collect experimental data to improve the predictive capability of wind plant computational models to represent the response of the turbine wake to varying inflow conditions and turbine operating states. The present work summarizes the experimental setup and illustrates several wake measurement example cases. The cases focus on demonstrating the impact of the atmospheric conditions on the wake shape and position, and exhibit a sample of the data that has been made public through the Department of Energy Atmosphere to Electrons Data Archive and Portal.

  20. Controllable printing droplets for high-resolution patterns.

    Science.gov (United States)

    Kuang, Minxuan; Wang, Libin; Song, Yanlin

    2014-10-29

    Inkjet printing has attracted wide attention due to the important applications in fabricating biological, optical, and electrical devices. During the inkjet printing process, the solutes prefer to deposit along the droplet periphery and form an inhomogeneous morphology, known as the coffee-ring effect. Besides, the feature size of printed dots or lines of conventional inkjet printing is usually limited to tens or even hundreds of micrometers. The above two issues greatly restrict the extensive application of printed patterns in high-performance devices. This paper reviews the recent advances in precisely controlling the printing droplets for high-resolution patterns and three-dimensional structures, with a focus on the development to suppress the coffee-ring effect and minimize the feature size of printed dots or lines. A perspective on the remaining challenges of the research is also proposed. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. High-resolution eye tracking using V1 neuron activity

    Science.gov (United States)

    McFarland, James M.; Bondy, Adrian G.; Cumming, Bruce G.; Butts, Daniel A.

    2014-01-01

    Studies of high-acuity visual cortical processing have been limited by the inability to track eye position with sufficient accuracy to precisely reconstruct the visual stimulus on the retina. As a result, studies on primary visual cortex (V1) have been performed almost entirely on neurons outside the high-resolution central portion of the visual field (the fovea). Here we describe a procedure for inferring eye position using multi-electrode array recordings from V1 coupled with nonlinear stimulus processing models. We show that this method can be used to infer eye position with one arc-minute accuracy – significantly better than conventional techniques. This allows for analysis of foveal stimulus processing, and provides a means to correct for eye-movement induced biases present even outside the fovea. This method could thus reveal critical insights into the role of eye movements in cortical coding, as well as their contribution to measures of cortical variability. PMID:25197783

  2. A compact high-resolution X-ray powder diffractometer.

    Science.gov (United States)

    Fewster, Paul F; Trout, David R D

    2013-12-01

    A new powder diffractometer operating in transmission mode is described. It can work as a rapid very compact instrument or as a high-resolution instrument, and the sample preparation is simplified. The incident beam optics create pure Cu K α 1 radiation, giving rise to peak widths of ∼0.1° in 2θ in compact form with a sample-to-detector minimum radius of 55 mm, reducing to peak widths of advantage of this geometry is that the resolution of the diffractometer can be calculated precisely and the instrumental artefacts can be analysed easily without a sample present. The performance is demonstrated with LaB 6 and paracetamol, and a critical appraisal of the uncertainties in the measurements is presented. The instantaneous data collection offers possibilities in dynamic experiments.

  3. THE HIGH-RESOLUTION INFRARED SPECTRUM OF HCl{sup +}

    Energy Technology Data Exchange (ETDEWEB)

    Doménech, J. L.; Herrero, V. J.; Tanarro, I. [Molecular Physics Department, Instituto de Estructura de la Materia (IEM-CSIC), Serrano 123, E-28006 Madrid (Spain); Drouin, B. J. [Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, Pasadena, CA 91109-8099 (United States); Cernicharo, J., E-mail: jl.domenech@csic.es [Molecular Astrophysics Group, Instituto de Ciencia de Materiales de Madrid (ICMM-CSIC), Sor Juana Inés de la Cruz 3, Cantoblanco, E-28049 Madrid (Spain)

    2016-12-20

    The chloroniumyl cation, HCl{sup +}, has been recently identified in space from Herschel 's spectra. A joint analysis of extensive vis-UV spectroscopy emission data together with a few high-resolution and high-accuracy millimeter-wave data provided the necessary rest frequencies to support the astronomical identification. Nevertheless, the analysis did not include any infrared (IR) vibration–rotation data. Furthermore, with the end of the Herschel mission, IR observations from the ground may be one of the few available means to further study this ion in space. In this work, we provide a set of accurate rovibrational transition wavenumbers, as well as a new and improved global fit of vis-UV, IR, and millimeter-wave spectroscopy laboratory data, that will aid in future studies of this molecule.

  4. High resolution ultrasound and photoacoustic imaging of single cells

    Directory of Open Access Journals (Sweden)

    Eric M. Strohm

    2016-03-01

    Full Text Available High resolution ultrasound and photoacoustic images of stained neutrophils, lymphocytes and monocytes from a blood smear were acquired using a combined acoustic/photoacoustic microscope. Photoacoustic images were created using a pulsed 532 nm laser that was coupled to a single mode fiber to produce output wavelengths from 532 nm to 620 nm via stimulated Raman scattering. The excitation wavelength was selected using optical filters and focused onto the sample using a 20× objective. A 1000 MHz transducer was co-aligned with the laser spot and used for ultrasound and photoacoustic images, enabling micrometer resolution with both modalities. The different cell types could be easily identified due to variations in contrast within the acoustic and photoacoustic images. This technique provides a new way of probing leukocyte structure with potential applications towards detecting cellular abnormalities and diseased cells at the single cell level.

  5. Realization of matching conditions for high-resolution spectrometers

    CERN Document Server

    Fujita, H; Berg, G P A; Bacher, A D; Foster, C C; Hara, K; Hatanaka, K; Kawabata, T; Noro, T; Sakaguchi, H; Shimbara, Y; Shinada, T; Stephenson, E J; Ueno, H; Yosoi, M

    2002-01-01

    For precise measurements of nuclear-reaction spectra using a beam from an accelerator, a high-resolution magnetic spectrometer is a powerful tool. The full capability of a magnetic spectrometer, however, can be achieved only if the characteristics of the beam coming from the accelerator are matched to those required by the spectrometer by properly adjusting the beam line conditions. The matching methods, lateral dispersion matching, focus matching and also the kinematic correction compensate the spectrum line-broadening effects caused by the beam momentum spread and reaction kinematics. In addition, angular dispersion matching should be performed if good resolution of the scattering angle is important. Diagnostic methods developed to realize these matching conditions for the spectrometers K600 at IUCF and Grand Raiden at RCNP are presented.

  6. Gravity Currents with Convective Mixing: High-resolution Numerical Simulations

    Science.gov (United States)

    Voskov, D.; Elenius, M. T.; Tchelepi, H.

    2014-12-01

    Due to challenges in performing direct numerical simulations for gravity currents with convective mixing, different attempts have been made to simplify the problem. In this work, the full problem is investigated with direct numerical simulations. Our simulations employ a recently developed capability in our General Purpose Research Simulator (AD-GPRS). The compositional approach is based on K-values and a linear density model. A shared-memory parallel implementation allows for high resolution simulations in a reasonable time frame. Our results indicate that it is important to consider the reduction in the dissolution rate after the fingers begin to interact with the bottom of the aquifer. Another important observation suggests considering a reduction in the dissolution rate where the plume thickness increases in time. In addition to the large-scale simulations, we performed convective-mixing simulations in relatively small domains to support the analysis of large-scale plume migration and CO2 trapping.

  7. High-resolution ZTE imaging of human teeth.

    Science.gov (United States)

    Weiger, Markus; Pruessmann, Klaas P; Bracher, Anna-Katinka; Köhler, Sascha; Lehmann, Volker; Wolfram, Uwe; Hennel, Franciszek; Rasche, Volker

    2012-10-01

    MRI with zero echo time (ZTE) is achieved by 3D radial centre-out encoding and hard-pulse RF excitation while the projection gradient is already on. Targeting short-T(2) samples, the efficient, robust and silent ZTE approach was implemented for high-bandwidth high-resolution imaging requiring particularly rapid transmit-receive switching and algebraic image reconstruction. The ZTE technique was applied to image extracted human teeth at 11.7T field strength, yielding detailed depictions with very good delineation of the mineralised dentine and enamel layers. ZTE results are compared with UTE (ultra-short echo time) MRI and micro-computed tomography (μCT), revealing significant differences in SNR and CNR yields. Compared to μCT, ZTE MRI appears to be less susceptible to artefacts caused by dental fillings and to offer superior sensitivity for the detection of early demineralisation and caries lesions. Copyright © 2012 John Wiley & Sons, Ltd.

  8. High resolution X-ray CT for advanced electronics packaging

    Science.gov (United States)

    Oppermann, M.; Zerna, T.

    2017-02-01

    Advanced electronics packaging is a challenge for non-destructive Testing (NDT). More, smaller and mostly hidden interconnects dominate modern electronics components and systems. To solve the demands of customers to get products with a high functionality by low volume, weight and price (e.g. mobile phones, personal medical monitoring systems) often the designers use System-in-Package solutions (SiP). The non-destructive testing of such devices is a big challenge. So our paper will impart fundamentals and applications for non-destructive evaluation of inner structures of electronics packaging for quality assurance and reliability investigations with a focus on X-ray methods, especially on high resolution X-ray computed tomography (CT).

  9. Multilayer Patterning of High Resolution Intrinsically Stretchable Electronics

    Science.gov (United States)

    Tybrandt, Klas; Stauffer, Flurin; Vörös, Janos

    2016-05-01

    Stretchable electronics can bridge the gap between hard planar electronic circuits and the curved, soft and elastic objects of nature. This has led to applications like conformal displays, electronic skin and soft neuroprosthetics. A remaining challenge, however, is to match the dimensions of the interfaced systems, as all require feature sizes well below 100 μm. Intrinsically stretchable nanocomposites are attractive in this context as the mechanical deformations occur on the nanoscale, although methods for patterning high performance materials have been lacking. Here we address these issues by reporting on a multilayer additive patterning approach for high resolution fabrication of stretchable electronic devices. The method yields highly conductive 30 μm tracks with similar performance to their macroscopic counterparts. Further, we demonstrate a three layer micropatterned stretchable electroluminescent display with pixel sizes down to 70 μm. These presented findings pave the way towards future developments of high definition displays, electronic skins and dense multielectrode arrays.

  10. Comparative Assessment of Very High Resolution Satellite and Aerial Orthoimagery

    Science.gov (United States)

    Agrafiotis, P.; Georgopoulos, A.

    2015-03-01

    This paper aims to assess the accuracy and radiometric quality of orthorectified high resolution satellite imagery from Pleiades-1B satellites through a comparative evaluation of their quantitative and qualitative properties. A Pleiades-B1 stereopair of high resolution images taken in 2013, two adjacent GeoEye-1 stereopairs from 2011 and aerial orthomosaic (LSO) provided by NCMA S.A (Hellenic Cadastre) from 2007 have been used for the comparison tests. As control dataset orthomosaic from aerial imagery provided also by NCMA S.A (0.25m GSD) from 2012 was selected. The process for DSM and orthoimage production was performed using commercial digital photogrammetric workstations. The two resulting orthoimages and the aerial orthomosaic (LSO) were relatively and absolutely evaluated for their quantitative and qualitative properties. Test measurements were performed using the same check points in order to establish their accuracy both as far as the single point coordinates as well as their distances are concerned. Check points were distributed according to JRC Guidelines for Best Practice and Quality Checking of Ortho Imagery and NSSDA standards while areas with different terrain relief and land cover were also included. The tests performed were based also on JRC and NSSDA accuracy standards. Finally, tests were carried out in order to assess the radiometric quality of the orthoimagery. The results are presented with a statistical analysis and they are evaluated in order to present the merits and demerits of the imaging sensors involved for orthoimage production. The results also serve for a critical approach for the usability and cost efficiency of satellite imagery for the production of Large Scale Orthophotos.

  11. Evaluation of a High-Resolution Regional Reanalysis for Europe

    Science.gov (United States)

    Ohlwein, C.; Wahl, S.; Keller, J. D.; Bollmeyer, C.

    2014-12-01

    Reanalyses gain more and more importance as a source of meteorological information for many purposes and applications. Several global reanalyses projects (e.g., ERA, MERRA, CSFR, JMA9) produce and verify these data sets to provide time series as long as possible combined with a high data quality. Due to a spatial resolution down to 50-70km and 3-hourly temporal output, they are not suitable for small scale problems (e.g., regional climate assessment, meso-scale NWP verification, input for subsequent models such as river runoff simulations). The implementation of regional reanalyses based on a limited area model along with a data assimilation scheme is able to generate reanalysis data sets with high spatio-temporal resolution. Within the Hans-Ertel-Centre for Weather Research (HErZ), the climate monitoring branch concentrates efforts on the assessment and analysis of regional climate in Germany and Europe. In joint cooperation with DWD (German Meteorological Service), a high-resolution reanalysis system based on the COSMO model has been developed. The regional reanalysis for Europe matches the domain of the CORDEX EURO-11 specifications, albeit at a higher spatial resolution, i.e., 0.055° (6km) instead of 0.11° (12km) and comprises the assimilation of observational data using the existing nudging scheme of COSMO complemented by a special soil moisture analysis with boundary conditions provided by ERA-Interim data. The reanalysis data set covers 6 years (2007-2012) and is currently extended to 16 years. Extensive evaluation of the reanalysis is performed using independent observations with special emphasis on precipitation and high-impact weather situations indicating a better representation of small scale variability. Further, the evaluation shows an added value of the regional reanalysis with respect to the forcing ERA Interim reanalysis and compared to a pure high-resolution dynamical downscaling approach without data assimilation.

  12. The high-resolution regional reanalysis COSMO-REA6

    Science.gov (United States)

    Ohlwein, C.

    2016-12-01

    Reanalyses gain more and more importance as a source of meteorological information for many purposes and applications. Several global reanalyses projects (e.g., ERA, MERRA, CSFR, JMA9) produce and verify these data sets to provide time series as long as possible combined with a high data quality. Due to a spatial resolution down to 50-70km and 3-hourly temporal output, they are not suitable for small scale problems (e.g., regional climate assessment, meso-scale NWP verification, input for subsequent models such as river runoff simulations). The implementation of regional reanalyses based on a limited area model along with a data assimilation scheme is able to generate reanalysis data sets with high spatio-temporal resolution. Within the Hans-Ertel-Centre for Weather Research (HErZ), the climate monitoring branch concentrates efforts on the assessment and analysis of regional climate in Germany and Europe. In joint cooperation with DWD (German Meteorological Service), a high-resolution reanalysis system based on the COSMO model has been developed. The regional reanalysis for Europe matches the domain of the CORDEX EURO-11 specifications, albeit at a higher spatial resolution, i.e., 0.055° (6km) instead of 0.11° (12km) and comprises the assimilation of observational data using the existing nudging scheme of COSMO complemented by a special soil moisture analysis with boundary conditions provided by ERA-Interim data. The reanalysis data set covers the past 20 years. Extensive evaluation of the reanalysis is performed using independent observations with special emphasis on precipitation and high-impact weather situations indicating a better representation of small scale variability. Further, the evaluation shows an added value of the regional reanalysis with respect to the forcing ERA Interim reanalysis and compared to a pure high-resolution dynamical downscaling approach without data assimilation.

  13. A High-resolution Reanalysis for the European CORDEX Region

    Science.gov (United States)

    Bentzien, Sabrina; Bollmeyer, Christoph; Crewell, Susanne; Friederichs, Petra; Hense, Andreas; Keller, Jan; Keune, Jessica; Kneifel, Stefan; Ohlwein, Christian; Pscheidt, Ieda; Redl, Stephanie; Steinke, Sandra

    2014-05-01

    A High-resolution Reanalysis for the European CORDEX Region Within the Hans-Ertel-Centre for Weather Research (HErZ), the climate monitoring branch concentrates efforts on the assessment and analysis of regional climate in Germany and Europe. In joint cooperation with DWD (German Meteorological Service), a high-resolution reanalysis system based on the COSMO model has been developed. Reanalyses gain more and more importance as a source of meteorological information for many purposes and applications. Several global reanalyses projects (e.g., ERA, MERRA, CSFR, JMA9) produce and verify these data sets to provide time series as long as possible combined with a high data quality. Due to a spatial resolution down to 50-70km and 3-hourly temporal output, they are not suitable for small scale problems (e.g., regional climate assessment, meso-scale NWP verification, input for subsequent models such as river runoff simulations). The implementation of regional reanalyses based on a limited area model along with a data assimilation scheme is able to generate reanalysis data sets with high spatio-temporal resolution. The work presented here focuses on the regional reanalysis for Europe with a domain matching the CORDEX-EURO-11 specifications, albeit at a higher spatial resolution, i.e., 0.055° (6km) instead of 0.11° (12km). The COSMO reanalysis system comprises the assimilation of observational data using the existing nudging scheme of COSMO and is complemented by a special soil moisture analysis and boundary conditions given by ERA-interim data. The reanalysis data set currently covers 6 years (2007-2012). The evaluation of the reanalyses is done using independent observations with special emphasis on precipitation and high-impact weather situations. The development and evaluation of the COSMO-based reanalysis for the CORDEX-Euro domain can be seen as a preparation for joint European activities on the development of an ensemble system of regional reanalyses for Europe.

  14. A high-resolution multimode digital microscope system.

    Science.gov (United States)

    Salmon, Edward D; Shaw, Sidney L; Waters, Jennifer C; Waterman-Storer, Clare M; Maddox, Paul S; Yeh, Elaine; Bloom, Kerry

    2013-01-01

    This chapter describes the development of a high-resolution, multimode digital imaging system based on a wide-field epifluorescent and transmitted light microscope, and a cooled charge-coupled device (CCD) camera. The three main parts of this imaging system are Nikon FXA microscope, Hamamatsu C4880 cooled CCD camera, and MetaMorph digital imaging system. This chapter presents various design criteria for the instrument and describes the major features of the microscope components-the cooled CCD camera and the MetaMorph digital imaging system. The Nikon FXA upright microscope can produce high resolution images for both epifluorescent and transmitted light illumination without switching the objective or moving the specimen. The functional aspects of the microscope set-up can be considered in terms of the imaging optics, the epi-illumination optics, the transillumination optics, the focus control, and the vibration isolation table. This instrument is somewhat specialized for microtubule and mitosis studies, and it is also applicable to a variety of problems in cellular imaging, including tracking proteins fused to the green fluorescent protein in live cells. The instrument is also valuable for correlating the assembly dynamics of individual cytoplasmic microtubules (labeled by conjugating X-rhodamine to tubulin) with the dynamics of membranes of the endoplasmic reticulum (labeled with DiOC6) and the dynamics of the cell cortex (by differential interference contrast) in migrating vertebrate epithelial cells. This imaging system also plays an important role in the analysis of mitotic mutants in the powerful yeast genetic system Saccharomyces cerevisiae. Copyright © 1998 Elsevier Inc. All rights reserved.

  15. High resolution 3D imaging of synchrotron generated microbeams

    Energy Technology Data Exchange (ETDEWEB)

    Gagliardi, Frank M., E-mail: frank.gagliardi@wbrc.org.au [Alfred Health Radiation Oncology, The Alfred, Melbourne, Victoria 3004, Australia and School of Medical Sciences, RMIT University, Bundoora, Victoria 3083 (Australia); Cornelius, Iwan [Imaging and Medical Beamline, Australian Synchrotron, Clayton, Victoria 3168, Australia and Centre for Medical Radiation Physics, University of Wollongong, Wollongong, New South Wales 2500 (Australia); Blencowe, Anton [Division of Health Sciences, School of Pharmacy and Medical Sciences, The University of South Australia, Adelaide, South Australia 5000, Australia and Division of Information Technology, Engineering and the Environment, Mawson Institute, University of South Australia, Mawson Lakes, South Australia 5095 (Australia); Franich, Rick D. [School of Applied Sciences and Health Innovations Research Institute, RMIT University, Melbourne, Victoria 3000 (Australia); Geso, Moshi [School of Medical Sciences, RMIT University, Bundoora, Victoria 3083 (Australia)

    2015-12-15

    Purpose: Microbeam radiation therapy (MRT) techniques are under investigation at synchrotrons worldwide. Favourable outcomes from animal and cell culture studies have proven the efficacy of MRT. The aim of MRT researchers currently is to progress to human clinical trials in the near future. The purpose of this study was to demonstrate the high resolution and 3D imaging of synchrotron generated microbeams in PRESAGE® dosimeters using laser fluorescence confocal microscopy. Methods: Water equivalent PRESAGE® dosimeters were fabricated and irradiated with microbeams on the Imaging and Medical Beamline at the Australian Synchrotron. Microbeam arrays comprised of microbeams 25–50 μm wide with 200 or 400 μm peak-to-peak spacing were delivered as single, cross-fire, multidirectional, and interspersed arrays. Imaging of the dosimeters was performed using a NIKON A1 laser fluorescence confocal microscope. Results: The spatial fractionation of the MRT beams was clearly visible in 2D and up to 9 mm in depth. Individual microbeams were easily resolved with the full width at half maximum of microbeams measured on images with resolutions of as low as 0.09 μm/pixel. Profiles obtained demonstrated the change of the peak-to-valley dose ratio for interspersed MRT microbeam arrays and subtle variations in the sample positioning by the sample stage goniometer were measured. Conclusions: Laser fluorescence confocal microscopy of MRT irradiated PRESAGE® dosimeters has been validated in this study as a high resolution imaging tool for the independent spatial and geometrical verification of MRT beam delivery.

  16. High resolution microphotonic needle for endoscopic imaging (Conference Presentation)

    Science.gov (United States)

    Tadayon, Mohammad Amin; Mohanty, Aseema; Roberts, Samantha P.; Barbosa, Felippe; Lipson, Michal

    2017-02-01

    GRIN (Graded index) lens have revolutionized micro endoscopy enabling deep tissue imaging with high resolution. The challenges of traditional GRIN lenses are their large size (when compared with the field of view) and their limited resolution. This is because of the relatively weak NA in standard graded index lenses. Here we introduce a novel micro-needle platform for endoscopy with much higher resolution than traditional GRIN lenses and a FOV that corresponds to the whole cross section of the needle. The platform is based on polymeric (SU-8) waveguide integrated with a microlens micro fabricated on a silicon substrate using a unique molding process. Due to the high index of refraction of the material the NA of the needle is much higher than traditional GRIN lenses. We tested the probe in a fluorescent dye solution (19.6 µM Alexa Flour 647 solution) and measured a numerical aperture of 0.25, focal length of about 175 µm and minimal spot size of about 1.6 µm. We show that the platform can image a sample with the field of view corresponding to the cross sectional area of the waveguide (80x100 µm2). The waveguide size can in principle be modified to vary size of the imaging field of view. This demonstration, combined with our previous work demonstrating our ability to implant the high NA needle in a live animal, shows that the proposed system can be used for deep tissue imaging with very high resolution and high field of view.

  17. Exploring for subtle traps with high-resolution paleogeographic maps

    Energy Technology Data Exchange (ETDEWEB)

    Bulling, T.B.; Breyer, J.A.

    1988-01-01

    High-resolution paleogeographic maps depicting the depositional history of the Reklaw 1 interval provide a basis for prospecting for subtle traps in the updip Reklaw trend in south Texas. The Reklaw 1 interval began with sand being carried southwest by longshore currents to form the barrier bar that forms the reservoir in Atkinson field. The hydrocarbons are trapped by the updip pinch-out of barrier-bar sand into lagoonal mud. Stratigraphic traps similar to Atkinson field could be present along depositional strike if the sand in the field were part of a more extensive-bar system. After the barrier bar formed, distributary-mouth bars prograded seaward depositing the bar-finger sands that are the reservoirs in Hysaw and Flax fields. Subtle structural traps could be present where small down-to-the-north faults associated with the Sample fault system cut the bar-finger sands downdip from the established production. Farther down paleoslope, the distributary channels began to bifurcate and the distributary-mouth bar coalesced to form a broad delt-front sheet sand. Burnell, Hondo Creek, and Runge West fields produce from this sheet sand near the unstable shelf margin. A rapid rise in relative sea level terminated deposition of the Reklaw 1 interval. Many of the oil and gas fields remaining to be discovered in the United States are in mature petroleum provinces where much of the remaining oil and gas probably resides in subtle traps. High-resolution paleogeographic maps may be a key to finding these subtle traps.

  18. Preliminary clinical evaluation of a high-resolution telemammography system.

    Science.gov (United States)

    Maitz, G S; Chang, T S; Sumkin, J H; Wintz, P W; Johns, C M; Ganott, M; Holbert, B L; Hakim, C M; Harris, K M; Gur, D; Herron, J M

    1997-04-01

    The authors designed, assembled, tested, and clinically evaluated a high-quality, fast, and relatively inexpensive telemammography system. The authors designed a telemammography system that uses a high-resolution film digitizer and high data compression (> or = 40:1) to send images over regular telephone lines to a high-resolution laser printer that produces images with the look and feel of the original image and can operate in a hub and spokes mode. The authors then evaluated the system's performance. In a preliminary clinical study, interpretations of the laser-printed system's output of 119 cases were compared with the original interpretations, followed by a review of any clinically significant differences. With the exception of the laser printer, which is a modified off-the-shelf product, all hardware components of the system are commercially available products. The system digitizes (50 microns pixel size), compresses, transmits, receives, decompresses, and prints a 30 MB mammography file in less than 4 minutes. In the clinical study, there were 13 differences (in 13 cases) in the level of concern or recommendations. Seven were found to be clinically insignificant by a third-party review. The remaining six were reviewed by the original interpreter, and three were determined to be significant enough for further action. All were found to result from intra-reader variability rather than differences in visualization of possible abnormalities. Almost real-time, high-quality telemammography without geographic boundaries is possible with the use of high-level data compression. Telemammography with laser-printed film as the display may make it possible to offer mammographic services in remote locations while using commercially available technology.

  19. High Resolution Stellar Spectroscopy with VBT Echelle Spectrometer

    Indian Academy of Sciences (India)

    the fiber position on a monitor in the control room from where guiding is done. The light from calibration lamps – Thorium–Argon for wavelength calibration and Xenon and Tungsten lamps for flat field, is also fed to the fiber through the same unit. The fiber output is collimated and converted to an f/5 converging beam that ...

  20. A High-Resolution Merged Wind Dataset for DYNAMO: Progress and Future Plans

    Science.gov (United States)

    Lang, Timothy J.; Mecikalski, John; Li, Xuanli; Chronis, Themis; Castillo, Tyler; Hoover, Kacie; Brewer, Alan; Churnside, James; McCarty, Brandi; Hein, Paul; hide

    2015-01-01

    In order to support research on optimal data assimilation methods for the Cyclone Global Navigation Satellite System (CYGNSS), launching in 2016, work has been ongoing to produce a high-resolution merged wind dataset for the Dynamics of the Madden Julian Oscillation (DYNAMO) field campaign, which took place during late 2011/early 2012. The winds are produced by assimilating DYNAMO observations into the Weather Research and Forecasting (WRF) three-dimensional variational (3DVAR) system. Data sources from the DYNAMO campaign include the upper-air sounding network, radial velocities from the radar network, vector winds from the Advanced Scatterometer (ASCAT) and Oceansat-2 Scatterometer (OSCAT) satellite instruments, the NOAA High Resolution Doppler Lidar (HRDL), and several others. In order the prep them for 3DVAR, significant additional quality control work is being done for the currently available TOGA and SMART-R radar datasets, including automatically dealiasing radial velocities and correcting for intermittent TOGA antenna azimuth angle errors. The assimilated winds are being made available as model output fields from WRF on two separate grids with different horizontal resolutions - a 3-km grid focusing on the main DYNAMO quadrilateral (i.e., Gan Island, the R/V Revelle, the R/V Mirai, and Diego Garcia), and a 1-km grid focusing on the Revelle. The wind dataset is focused on three separate approximately 2-week periods during the Madden Julian Oscillation (MJO) onsets that occurred in October, November, and December 2011. Work is ongoing to convert the 10-m surface winds from these model fields to simulated CYGNSS observations using the CYGNSS End-To-End Simulator (E2ES), and these simulated satellite observations are being compared to radar observations of DYNAMO precipitation systems to document the anticipated ability of CYGNSS to provide information on the relationships between surface winds and oceanic precipitation at the mesoscale level. This research will

  1. Uncertainty of soil erosion modelling using open source high resolution and aggregated DEMs

    Directory of Open Access Journals (Sweden)

    Arun Mondal

    2017-05-01

    Full Text Available Digital Elevation Model (DEM is one of the important parameters for soil erosion assessment. Notable uncertainties are observed in this study while using three high resolution open source DEMs. The Revised Universal Soil Loss Equation (RUSLE model has been applied to analysis the assessment of soil erosion uncertainty using open source DEMs (SRTM, ASTER and CARTOSAT and their increasing grid space (pixel size from the actual. The study area is a part of the Narmada river basin in Madhya Pradesh state, which is located in the central part of India and the area covered 20,558 km2. The actual resolution of DEMs is 30 m and their increasing grid spaces are taken as 90, 150, 210, 270 and 330 m for this study. Vertical accuracy of DEMs has been assessed using actual heights of the sample points that have been taken considering planimetric survey based map (toposheet. Elevations of DEMs are converted to the same vertical datum from WGS 84 to MSL (Mean Sea Level, before the accuracy assessment and modelling. Results indicate that the accuracy of the SRTM DEM with the RMSE of 13.31, 14.51, and 18.19 m in 30, 150 and 330 m resolution respectively, is better than the ASTER and the CARTOSAT DEMs. When the grid space of the DEMs increases, the accuracy of the elevation and calculated soil erosion decreases. This study presents a potential uncertainty introduced by open source high resolution DEMs in the accuracy of the soil erosion assessment models. The research provides an analysis of errors in selecting DEMs using the original and increased grid space for soil erosion modelling.

  2. High-Resolution Stratospheric Tracer Fields Reconstructed with Lagrangian Techniques: A Comparative Analysis of Predictive Skill.

    Science.gov (United States)

    Dragani, R.; Redaelli, G.; Visconti, G.; Mariotti, A.; Rudakov, V.; MacKenzie, A. R.; Stefanutti, L.

    2002-06-01

    Numerical experiments and statistical analyses are conducted to determine the skill of different Lagrangian techniques for the construction of tracer distributions. High-resolution potential vorticity (PV) maps are calculated from simulations of the 1996/97 arctic winter stratospheric dynamics using two different numerical schemes-reverse domain filling trajectories (RDF) and contour advection with surgery (CAS)-and data from three meteorological agencies (NCEP, the Met Office, and ECMWF). The PV values are then converted into ozone (O3) concentrations and statistically compared to in situ O3 data measured by the electro chemical ozone cell (ECOC) instrument during the Airborne Polar Experiment (APE) using cross correlation, rms differences, and the Kolmogorov-Smirnov (KS) test.Results indicate that while Lagrangian techniques are successful in increasing the presence of lower-scale tracer structures with respect to the plain meteorological analyses, they significantly improve the statistical agreement between the simulated and the measured tracer profiles only when there is clear evidence of filaments in the measured data. This better fit is most clearly seen by using the KS test, rather than cross correlation. It is argued that this difference in the performance of Lagrangian techniques can be partly related to the treatment of mixing processes in the framework of the Lagrangian schemes. Statistical analyses also show that the temporal rather than the spatial resolution of the input meteorological fields, used to advect tracers, enhances the predictive skill of the Lagrangian products. The best overall performance is obtained with the Lagrangian product (not gridded) based on high-resolution reverse trajectories calculated along a flight track, in particular when the simulation is initialized with ECMWF data. Other products, such as CAS initialized with ECMWF and 3D-gridded RDF initialized with the Met Office data, show fairly good performances, thus with lower

  3. Convertible barge

    Energy Technology Data Exchange (ETDEWEB)

    Howson, R.E.

    1988-08-23

    This patent describes a convertible barge, comprising: a. a deck; b. modules positioned on the deck in end to end relation and at least some of which contain pipeline processing equipment. The modules being removably attached to the deck, each module comprising a floor, ceiling, and a pair of side walls extending longitudinally of the barge between the ends; and c. means defining a closable opening comprising a roll-up door in at least one end of the modules for passing a pipeline portion from the module to a respectively adjacent module as the pipeline is being processed, for sealing the module during storage and for providing passageways between the modules and a view of pipe laying operations during use. A method for converting a barge to a lay barge, comprising: a. positioning on a deck of the barge in end to end relation of modules each of which has a floor, ceiling, and a pair of sidewalls extending longitudinally of the barge between the ends; b. providing pipeline process stations in at least some of the modules; c. removably attaching the modules to the deck; and d. providing a roll-up door in at least one of the modules ends of each module for passing a pipeline portion from the module to a respectively adjacent module as the pipeline is being processed and for providing passageways between the modules and a view of pipe laying operations during use.

  4. Seismic investigations for high resolution exploration ahead and around boreholes

    Science.gov (United States)

    Jaksch, Katrin; Giese, Ruediger; Kopf, Matthias

    2013-04-01

    Deep reservoirs usually will be explored with a surface seismic survey often in combination with borehole seismic measurements like VSP or SWD which can improve the velocity model of the underground. Reservoirs especially in geothermal fields are often characterized by small-scale structures. Additionally, with depth the need for exploration methods with a high resolution increases because standard methods like borehole seismic measurements cannot improve their resolution with depth. To localize structures with more accuracy methods with higher resolution in the range of meters are necessary. Within the project SPWD - Seismic Prediction While Drilling a new exploration method will be developed. With an implementation of seismic sources and receivers in one device an exploration method ahead and around the borehole will be enabled. Also, a high resolution independent from the depth will be achieved. Therefore active and powerful seismic sources are necessary to reach an acceptable penetration depth. Step by step seismic borehole devices were developed, which can be used under different conditions. Every borehole device contains four seismic sources and several three-component geophones. A small distance between actuators and geophones allows detecting also the high frequency content of the wave field reflected at geological structures. Also, exploration with a high resolution is possible. A first borehole device was developed for basic conditions in horizontal boreholes without special terms to temperature or pressure. In a mine first methodical measurements for the initiated wave field were performed. Therefor an existing seismic test area at the research and education mine of the TU Bergakademie Freiberg was extended with boreholes. In the seismic test area, consisting of a dense geophone array with three-component geophone anchors, two horizontal and one vertical borehole was drilled. To achieve a radiation pattern in predefined directions by constructive

  5. A new high-resolution electromagnetic method for subsurface imaging

    Science.gov (United States)

    Feng, Wanjie

    For most electromagnetic (EM) geophysical systems, the contamination of primary fields on secondary fields ultimately limits the capability of the controlled-source EM methods. Null coupling techniques were proposed to solve this problem. However, the small orientation errors in the null coupling systems greatly restrict the applications of these systems. Another problem encountered by most EM systems is the surface interference and geologic noise, which sometimes make the geophysical survey impossible to carry out. In order to solve these problems, the alternating target antenna coupling (ATAC) method was introduced, which greatly removed the influence of the primary field and reduced the surface interference. But this system has limitations on the maximum transmitter moment that can be used. The differential target antenna coupling (DTAC) method was proposed to allow much larger transmitter moments and at the same time maintain the advantages of the ATAC method. In this dissertation, first, the theoretical DTAC calculations were derived mathematically using Born and Wolf's complex magnetic vector. 1D layered and 2D blocked earth models were used to demonstrate that the DTAC method has no responses for 1D and 2D structures. Analytical studies of the plate model influenced by conductive and resistive backgrounds were presented to explain the physical phenomenology behind the DTAC method, which is the magnetic fields of the subsurface targets are required to be frequency dependent. Then, the advantages of the DTAC method, e.g., high-resolution, reducing the geologic noise and insensitive to surface interference, were analyzed using surface and subsurface numerical examples in the EMGIMA software. Next, the theoretical advantages, such as high resolution and insensitive to surface interference, were verified by designing and developing a low-power (moment of 50 Am 2) vertical-array DTAC system and testing it on controlled targets and scaled target coils. At last, a

  6. High resolution multi-scalar drought indices for Iberia

    Science.gov (United States)

    Russo, Ana; Gouveia, Célia; Trigo, Ricardo; Jerez, Sonia

    2014-05-01

    The Iberian Peninsula has been recurrently affected by drought episodes and by adverse associated effects (Gouveia et al., 2009), ranging from severe water shortages to losses of hydroelectricity production, increasing risk of forest fires, forest decline and triggering processes of land degradation and desertification. Moreover, Iberia corresponds to one of the most sensitive areas to current and future climate change and is nowadays considered a hot spot of climate change with high probability for the increase of extreme events (Giorgi and Lionello, 2008). The spatial and temporal behavior of climatic droughts at different time scales was analyzed using spatially distributed time series of multi-scalar drought indicators, such as the Standardized Precipitation Evapotranspiration Index (SPEI) (Vicente-Serrano et al., 2010). This new climatic drought index is based on the simultaneous use of precipitation and temperature fields with the advantage of combining a multi-scalar character with the capacity to include the effects of temperature variability on drought assessment. Moreover, reanalysis data and the higher resolution hindcasted databases obtained from them are valuable surrogates of the sparse observations and widely used for in-depth characterizations of the present-day climate. Accordingly, this work aims to enhance the knowledge on high resolution drought patterns in Iberian Peninsula, taking advantage of high-resolution (10km) regional MM5 simulations of the recent past (1959-2007) over Iberia. It should be stressed that these high resolution meteorological fields (e.g. temperature, precipitation) have been validated for various purposes (Jerez et al., 2013). A detailed characterization of droughts since the 1960s using the 10 km resolution hidncasted simulation was performed with the aim to explore the conditions favoring drought onset, duration and ending, as well as the subsequent short, medium and long-term impacts affecting the environment and the

  7. Segmentation Based Fuzzy Classification of High Resolution Images

    Science.gov (United States)

    Rao, Mukund; Rao, Suryaprakash; Masser, Ian; Kasturirangan, K.

    images, we build a much needed bridge between the methodology domains of GIS and Image Analysis. The idea of having an integrated 'geographical information processing' environment is becoming much more realistic now that 'GIS' objects can be used for analysing an image and vice versa, new 'GIS' objects can be directly generated without ignoring the rich information environment of geographical concepts, relations and scales. In the above scenario, the main aim of this project is to assess whether object-oriented classification techniques would be more suitable for remote sensing images - specifically in the context of high resolution images. The paper basically examines potentials of classification techniques - especially segmentation based methods that is based on an object-semantics and that uses not only the spectral information but also the spatial characteristics; studies the integration of segmentation and fuzzy-classification to derive user-oriented information from the high resolution images and evaluates how such segmentation based classification compares with the more common pixel- based statistical technique. Segmentation based fuzzy classification is applied to high resolution images from IRS and for 1m images from satellites - especially to extract urban information.

  8. Spatial Ensemble Postprocessing of Precipitation Forecasts Using High Resolution Analyses

    Science.gov (United States)

    Lang, Moritz N.; Schicker, Irene; Kann, Alexander; Wang, Yong

    2017-04-01

    Ensemble prediction systems are designed to account for errors or uncertainties in the initial and boundary conditions, imperfect parameterizations, etc. However, due to sampling errors and underestimation of the model errors, these ensemble forecasts tend to be underdispersive, and to lack both reliability and sharpness. To overcome such limitations, statistical postprocessing methods are commonly applied to these forecasts. In this study, a full-distributional spatial post-processing method is applied to short-range precipitation forecasts over Austria using Standardized Anomaly Model Output Statistics (SAMOS). Following Stauffer et al. (2016), observation and forecast fields are transformed into standardized anomalies by subtracting a site-specific climatological mean and dividing by the climatological standard deviation. Due to the need of fitting only a single regression model for the whole domain, the SAMOS framework provides a computationally inexpensive method to create operationally calibrated probabilistic forecasts for any arbitrary location or for all grid points in the domain simultaneously. Taking advantage of the INCA system (Integrated Nowcasting through Comprehensive Analysis), high resolution analyses are used for the computation of the observed climatology and for model training. The INCA system operationally combines station measurements and remote sensing data into real-time objective analysis fields at 1 km-horizontal resolution and 1 h-temporal resolution. The precipitation forecast used in this study is obtained from a limited area model ensemble prediction system also operated by ZAMG. The so called ALADIN-LAEF provides, by applying a multi-physics approach, a 17-member forecast at a horizontal resolution of 10.9 km and a temporal resolution of 1 hour. The performed SAMOS approach statistically combines the in-house developed high resolution analysis and ensemble prediction system. The station-based validation of 6 hour precipitation sums

  9. Diagnostic value of high resolutional computed tomography of spine

    Energy Technology Data Exchange (ETDEWEB)

    Yang, S. M.; Im, S. K.; Sohn, M. H.; Lim, K. Y.; Kim, J. K.; Choi, K. C. [Jeonbug National University College of Medicine, Seoul (Korea, Republic of)

    1984-03-15

    Non-enhanced high resolution computed tomography provide clear visualization of soft tissue in the canal and bony details of spine, particularly of the lumbar spine. We observed 70 cases of spine CT using GE CT/T 8800 scanner during the period from Dec. 1982 to Sep. 1983 at Jeonbug National University Hospital. The results were as follows: 1. The sex distribution of cases were 55 males and 15 females : age was from 17 years to 67 years; sites were 11 cervical spine, 5 thoracic spine and 54 lumbosacral spine. 2. CT diagnosis showed 44 cases of lumbar disc herniation, 7 cases of degenerative disease, 3 cases of spine fracture and each 1 cases of cord tumor, metastatic tumor, spontaneous epidural hemorrhage, epidural abscess, spine tbc., meningocele with diastematomyelia. 3. Sites of herniated nucleus pulposus were 34 cases (59.6%) between L4-5 interspace and 20 cases (35.1%) between L5-S1 interspace. 13 cases (29.5%) of lumbar disc herniation disclosed multiple lesions. Location of herniation were central type in 28 cases(49.1%), right-central type in 12 cases(21.2%), left-central type in 11 cases (19.2%) and far lateral type in 6 cases(10.5%). 4. CT findings of herniated nucleus pulposus were as follows : focal protrusion of posterior disc margin and obliteration of anterior epidural fat in all cases, dural sac indentation in 26 cases(45.6%), soft tissue mass in epidural fat in 21 cases(36.8%), displacement or compression of nerve root sheath in 12 cases(21%). 5. Multiplanar reformatted images and Blink mode provide more effective evaluation about definite level and longitudinal dimension of lesion, such as obscure disc herniation, spine fracture, cord tumor and epidural abscess. 6. Non-enhanced and enhanced high resolutional computed tomography were effectively useful in demonstrating compression or displacement of spinal cord and nerve root, examing congenital anomaly such as meningocele and primary or metastatic spinal lesions.

  10. Precision cosmology with time delay lenses: High resolution imaging requirements

    Energy Technology Data Exchange (ETDEWEB)

    Meng, Xiao -Lei [Beijing Normal Univ., Beijing (China); Univ. of California, Santa Barbara, CA (United States); Treu, Tommaso [Univ. of California, Santa Barbara, CA (United States); Univ. of California, Los Angeles, CA (United States); Agnello, Adriano [Univ. of California, Santa Barbara, CA (United States); Univ. of California, Los Angeles, CA (United States); Auger, Matthew W. [Univ. of Cambridge, Cambridge (United Kingdom); Liao, Kai [Beijing Normal Univ., Beijing (China); Univ. of California, Santa Barbara, CA (United States); Univ. of California, Los Angeles, CA (United States); Marshall, Philip J. [Stanford Univ., Stanford, CA (United States)

    2015-09-28

    Lens time delays are a powerful probe of cosmology, provided that the gravitational potential of the main deflector can be modeled with sufficient precision. Recent work has shown that this can be achieved by detailed modeling of the host galaxies of lensed quasars, which appear as ``Einstein Rings'' in high resolution images. The distortion of these arcs and counter-arcs, as measured over a large number of pixels, provides tight constraints on the difference between the gravitational potential between the quasar image positions, and thus on cosmology in combination with the measured time delay. We carry out a systematic exploration of the high resolution imaging required to exploit the thousands of lensed quasars that will be discovered by current and upcoming surveys with the next decade. Specifically, we simulate realistic lens systems as imaged by the Hubble Space Telescope (HST), James Webb Space Telescope (JWST), and ground based adaptive optics images taken with Keck or the Thirty Meter Telescope (TMT). We compare the performance of these pointed observations with that of images taken by the Euclid (VIS), Wide-Field Infrared Survey Telescope (WFIRST) and Large Synoptic Survey Telescope (LSST) surveys. We use as our metric the precision with which the slope γ' of the total mass density profile ρtot∝ r–γ' for the main deflector can be measured. Ideally, we require that the statistical error on γ' be less than 0.02, such that it is subdominant to other sources of random and systematic uncertainties. We find that survey data will likely have sufficient depth and resolution to meet the target only for the brighter gravitational lens systems, comparable to those discovered by the SDSS survey. For fainter systems, that will be discovered by current and future surveys, targeted follow-up will be required. Furthermore, the exposure time required with upcoming facilitites such as JWST, the Keck Next Generation Adaptive

  11. High-resolution esophageal pressure topography for esophageal motility disorders

    Directory of Open Access Journals (Sweden)

    Hashem Fakhre Yaseri

    2016-04-01

    Full Text Available Background: High-resolution manometer (HRM of the esophagus has become the main diagnostic test in the evaluation of esophageal motility disorders. The development of high-resolution manometry catheters and software displays of manometry recordings in color-coded pressure plots have changed the diagnostic assessment of esophageal disease. The first step of the Chicago classification described abnormal esophagogastric junction deglutitive relaxation. The latest classification system, proposed by Pandolfino et al, includes contraction patterns and peristalsis integrity based on integrated relaxation pressure 4 (IRP4. It can be discriminating the achalasia from non-achalasia esophageal motility disorders. The aim of this study was to assessment of clinical findings in non-achalasia esophageal motility disorders based on the most recent Chicago classification. Methods: We conducted a prospective cross-sectional study of 963 patients that had been referred to manometry department of Gastrointestinal and Liver Research Center, Firozgar Hospital, Tehran, Iran, from April, 2012 to April, 2015. They had upper GI disorder (Dysphasia, non-cardiac chest pain, regurgitation, heartburn, vomiting and asthma and weight loss. Data were collected from clinical examinations as well as patient questionnaires. Manometry, water-perfused, was done for all patients. Manometry criteria of the patients who had integrated relaxation pressure 4 (IRP4 ≤ 15 mmHg were studied. Results: Our finding showed that the non-achalasia esophageal motility disorders (58% was more common than the achalasia (18.2%. Heartburn (68.5%, regurgitation (65.4% and non-cardiac chest pain (60.6% were the most common clinical symptoms. Although, vomiting (91.7% and weight loss (63% were the most common symptoms in referring patients but did not discriminate this disorders from each other’s. Borderline motor function (67.2% was the most common, absent peristalsis (97% and the hyper

  12. High-Resolution Force Balance Analyses of Tidewater Glacier Dynamics

    Science.gov (United States)

    Enderlin, E. M.; Hamilton, G. S.; O'Neel, S.

    2015-12-01

    Changes in glacier velocity, thickness, and terminus position have been used to infer the dynamic response of tidewater glaciers to environmental perturbations, yet few analyses have attempted to quantify the associated variations in the glacier force balance. Where repeat high-resolution ice thickness and velocity estimates are available, force balance time series can be constructed to investigate the redistribution of driving and resistive forces associated with changes in terminus position. Comparative force balance analyses may, therefore, help us understand the variable dynamic response observed for glaciers in close proximity to each other. Here we construct force balance time series for Helheim Glacier, SE Greenland, and Columbia Glacier, SE Alaska, to investigate differences in dynamic sensitivity to terminus position change. The analysis relies on in situ and remotely sensed observations of ice thickness, velocity, and terminus position. Ice thickness time series are obtained from stereo satellite image-derived surface elevation and continuity-derived bed elevations that are constrained by airborne radar observations. Surface velocity time series are obtained from interferometric synthetic aperture radar (InSAR) observations. Approximately daily terminus positions are from a combination of satellite images and terrestrial time-lapse photographs. Helheim and Columbia glaciers are two of the best-studied Arctic tidewater glaciers with comprehensive high-resolution observational time series, yet we find that bed elevation uncertainties and poorly-constrained stress-coupling length estimates still hinder the analysis of spatial and temporal force balance variations. Here we use a new observationally-based method to estimate the stress-coupling length which successfully reduces noise in the derived force balance but preserves spatial variations that can be over-smoothed when estimating the stress-coupling length as a scalar function of the ice thickness

  13. A new high-resolution climatology for the Nordic Seas

    Science.gov (United States)

    Korablev, A.; Johannessen, O. M.; Pnyushkov, A.; Smirnov, A.

    2009-04-01

    Constantly growing interests in high-resolution oceanographic fields stimulate compilation of comprehensive initial datasets and advanced methodology of the objective analysis. Observed level database for the Nordic Seas and the North Atlantic compiled from large amount of initial sources was recently considerably updated by adding historical and modern measurements. Improved database allows evaluating ocean climate variability in the area for 1900-2007. Applied quality control algorithms on observed data were specifically designed to preserve regional variability and to produce the oceanographic fields with enhanced spatial resolution. Objectively analyzed (OA) temperature, salinity and dissolved oxygen monthly fields at the standard levels for the 1900-2007 on 0.25 x 0.5 gr. latitude-longitude grid were computed by means of block variant of ordinary kriging system. The OA monthly fields comprise climatology and can be used for studying of temporal and spatial parameters variation. A number of stable regimes and periods with abrupt changes of the water masses thermohaline properties were identified and will be discussed. Monthly mean fields were compared with available high-resolution (better then 0.5 gr.) climatology fields, including Generalized Digital Environmental Model (GDEM) version 3.0 and NODC/NOAA products based on data from World Ocean Databases 2001 and 2005. Results show considerable discrepancies originated from differences in initial datasets, quality control algorithms and methods of objective analysis. Allocation of the collected oceanographic stations for more than one century and derived climatological fields over the Nordic Seas reveals a disproportion in data coverage. Repeated standard stations, sections and polygons are most important for uniform long-term time series compositing and ocean climate variation study. Luck of observations over the west and northern parts of the region do not allows reliable climatology fields compilation

  14. The high resolution mapping of the Venice Lagoon tidal network

    Science.gov (United States)

    Madricardo, Fantina; Foglini, Federica; Kruss, Aleksandra; Bellafiore, Debora; Trincardi, Fabio

    2017-04-01

    One of the biggest challenges of the direct observation of the ocean is to achieve a high resolution mapping of its seafloor morphology and benthic habitats. So far, sonars have mapped just 0.05% of the ocean floor with less than ten-meter resolution. The recent efforts of the scientific community have been devoted towards the mapping of both Deep Ocean and very shallow coastal areas. Coastal and transitional environments in particular undergo strong morphological changes due to natural and anthropogenic pressure. Nowadays, only about 5% of the seafloor of these environments † have been mapped: the shallowness of these environments has prevented the use of underwater acoustics to reveal their morphological features. The recent technological development of multibeam echosounder systems, however, enables these instruments to achieve very high performances also in such shallow environments. In this work, we present results and case studies of an extensive multibeam survey carried out in the Lagoon of Venice in 2013. The Lagoon of Venice is the biggest lagoon in the Mediterranean Sea with a surface of about 550 km2 and with an average depth of about 1 m. In the last century, the morphological and ecological properties of the lagoon changed dramatically: the surface of the salt marshes was reduced by 60% and some parts of the lagoon are deepening with a net sediment flux exiting from the inlets. Moreover, major engineering interventions are currently ongoing at the inlets (MOSE project). These changes at the inlets could affect substantially the lagoon environment. To understand and monitor the future evolution of the Lagoon of Venice, ISMAR within the project RITMARE (a National Research Programme funded by the Italian Ministry of University and Research) carried out an extensive survey, involving a team of more than 25 scientists, to collect high resolution (0.5 m) bathymetry of key study areas such as the tidal inlets and channels. Following a broad

  15. Managing the explosion of high resolution topography in the geosciences

    Science.gov (United States)

    Crosby, Christopher; Nandigam, Viswanath; Arrowsmith, Ramon; Phan, Minh; Gross, Benjamin

    2017-04-01

    Centimeter to decimeter-scale 2.5 to 3D sampling of the Earth surface topography coupled with the potential for photorealistic coloring of point clouds and texture mapping of meshes enables a wide range of science applications. Not only is the configuration and state of the surface as imaged valuable, but repeat surveys enable quantification of topographic change (erosion, deposition, and displacement) caused by various geologic processes. We are in an era of ubiquitous point clouds that come from both active sources such as laser scanners and radar as well as passive scene reconstruction via structure from motion (SfM) photogrammetry. With the decreasing costs of high-resolution topography (HRT) data collection, via methods such as SfM and UAS-based laser scanning, the number of researchers collecting these data is increasing. These "long-tail" topographic data are of modest size but great value, and challenges exist to making them widely discoverable, shared, annotated, cited, managed and archived. Presently, there are no central repositories or services to support storage and curation of these datasets. The U.S. National Science Foundation funded OpenTopography (OT) Facility employs cyberinfrastructure including large-scale data management, high-performance computing, and service-oriented architectures, to provide efficient online access to large HRT (mostly lidar) datasets, metadata, and processing tools. With over 225 datasets and 15,000 registered users, OT is well positioned to provide curation for community collected high-resolution topographic data. OT has developed a "Community DataSpace", a service built on a low cost storage cloud (e.g. AWS S3) to make it easy for researchers to upload, curate, annotate and distribute their datasets. The system's ingestion workflow will extract metadata from data uploaded; validate it; assign a digital object identifier (DOI); and create a searchable catalog entry, before publishing via the OT portal. The OT Community

  16. High-resolution analysis of the mechanical behavior of tissue

    Science.gov (United States)

    Hudnut, Alexa W.; Armani, Andrea M.

    2017-06-01

    The mechanical behavior and properties of biomaterials, such as tissue, have been directly and indirectly connected to numerous malignant physiological states. For example, an increase in the Young's Modulus of tissue can be indicative of cancer. Due to the heterogeneity of biomaterials, it is extremely important to perform these measurements using whole or unprocessed tissue because the tissue matrix contains important information about the intercellular interactions and the structure. Thus, developing high-resolution approaches that can accurately measure the elasticity of unprocessed tissue samples is of great interest. Unfortunately, conventional elastography methods such as atomic force microscopy, compression testing, and ultrasound elastography either require sample processing or have poor resolution. In the present work, we demonstrate the characterization of unprocessed salmon muscle using an optical polarimetric elastography system. We compare the results of compression testing within different samples of salmon skeletal muscle with different numbers of collagen membranes to characterize differences in heterogeneity. Using the intrinsic collagen membranes as markers, we determine the resolution of the system when testing biomaterials. The device reproducibly measures the stiffness of the tissues at variable strains. By analyzing the amount of energy lost by the sample during compression, collagen membranes that are 500 μm in size are detected.

  17. COSMIC: somatic cancer genetics at high-resolution.

    Science.gov (United States)

    Forbes, Simon A; Beare, David; Boutselakis, Harry; Bamford, Sally; Bindal, Nidhi; Tate, John; Cole, Charlotte G; Ward, Sari; Dawson, Elisabeth; Ponting, Laura; Stefancsik, Raymund; Harsha, Bhavana; Kok, Chai Yin; Jia, Mingming; Jubb, Harry; Sondka, Zbyslaw; Thompson, Sam; De, Tisham; Campbell, Peter J

    2017-01-04

    COSMIC, the Catalogue of Somatic Mutations in Cancer (http://cancer.sanger.ac.uk) is a high-resolution resource for exploring targets and trends in the genetics of human cancer. Currently the broadest database of mutations in cancer, the information in COSMIC is curated by expert scientists, primarily by scrutinizing large numbers of scientific publications. Over 4 million coding mutations are described in v78 (September 2016), combining genome-wide sequencing results from 28 366 tumours with complete manual curation of 23 489 individual publications focused on 186 key genes and 286 key fusion pairs across all cancers. Molecular profiling of large tumour numbers has also allowed the annotation of more than 13 million non-coding mutations, 18 029 gene fusions, 187 429 genome rearrangements, 1 271 436 abnormal copy number segments, 9 175 462 abnormal expression variants and 7 879 142 differentially methylated CpG dinucleotides. COSMIC now details the genetics of drug resistance, novel somatic gene mutations which allow a tumour to evade therapeutic cancer drugs. Focusing initially on highly characterized drugs and genes, COSMIC v78 contains wide resistance mutation profiles across 20 drugs, detailing the recurrence of 301 unique resistance alleles across 1934 drug-resistant tumours. All information from the COSMIC database is available freely on the COSMIC website. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

  18. High-Resolution EUV Spectroscopy of White Dwarfs

    Science.gov (United States)

    Kowalski, Michael P.; Wood, K. S.; Barstow, M. A.

    2014-01-01

    We compare results of high-resolution EUV spectroscopic measurements of the isolated white dwarf G191-B2B and the binary system Feige 24 obtained with the J-PEX (Joint Plasmadynamic Experiment), which was sponsored jointly by the U.S. Naval Research Laboratory and NASA. J-PEX delivers the world's highest resolution in EUV and does so at high effective area (e.g., more effective area in a sounding rocket than is available with Chandra at adjacent energies, but in a waveband Chandra cannot reach). The capability J-PEX represents is applicable to the astrophysics of hot plasmas in stellar coronae, white dwarfs and the ISM. G191-B2B and Feige 24 are quite distinct hot white dwarf systems having in common that they are bright in the portion of the EUV where He emission features and edges occur, hence they can be exploited to probe both the stellar atmosphere and the ISM, separating those components by model-fitting that sums over all relevant (He) spectral features in the band. There is evidence from these fits that atmospheric He is being detected but the result is more conservatively cast as a pair of upper limits. We discuss how longer duration satellite observations with the same instrumentation could increase exposure to detect atmospheric He in these and other nearby hot white dwarfs.

  19. Regional High Resolution Reanalysis Covered European North East Shelf

    Science.gov (United States)

    Bourdalle-Badie, R.; Benkiran, M.; Chanut, J.; Drillet, Y.; Reffray, G.

    2011-12-01

    Mercator-Ocean has developed a regional forecasting system at 1/12° resolution over the North East Atlantic (IBI: Iberia, Biscay and Irish), taking advantage of the recent developments in NEMO. This regional forecasting system uses boundary conditions from the Mercator-Ocean global reanalysis (GLORYS: Global Ocean ReanalYses and Simulations). The assimilation component of the Mercator Ocean system, is based on a reduced-order Kalman filter (the SEEK or Singular Extended Evolutive Kalman filter). An IAU method (Incremental Analysis Updates) is used to apply the increments in the system. The error statistics are represented in a sub-space spanned by a small number of dominant 3D error directions. The data assimilation system allows to constrain the model in a multivariate way with Sea Surface Temperature (AVHRR + Multi-satellite High resolution), together with all available satellite Sea Level Anomalies, and with in situ observations from the CORA-03 data base, including ARGO floats temperature and salinity measurements. This reanalysis covers the period from January 2002 to December 2009. In this presentation, the results obtained with this reanalysis system (1/12°) are compared to the GLORYS ones. A special focus will be made on the gain thanks to the higher resolution of the model and higher resolution of the SST assimilated in this reanalysis.

  20. High-resolution multimodal clinical multiphoton tomography of skin

    Science.gov (United States)

    König, Karsten

    2011-03-01

    This review focuses on multimodal multiphoton tomography based on near infrared femtosecond lasers. Clinical multiphoton tomographs for 3D high-resolution in vivo imaging have been placed into the market several years ago. The second generation of this Prism-Award winning High-Tech skin imaging tool (MPTflex) was introduced in 2010. The same year, the world's first clinical CARS studies have been performed with a hybrid multimodal multiphoton tomograph. In particular, non-fluorescent lipids and water as well as mitochondrial fluorescent NAD(P)H, fluorescent elastin, keratin, and melanin as well as SHG-active collagen has been imaged with submicron resolution in patients suffering from psoriasis. Further multimodal approaches include the combination of multiphoton tomographs with low-resolution wide-field systems such as ultrasound, optoacoustical, OCT, and dermoscopy systems. Multiphoton tomographs are currently employed in Australia, Japan, the US, and in several European countries for early diagnosis of skin cancer, optimization of treatment strategies, and cosmetic research including long-term testing of sunscreen nanoparticles as well as anti-aging products.

  1. Quantitative evolutionary dynamics using high-resolution lineage tracking.

    Science.gov (United States)

    Levy, Sasha F; Blundell, Jamie R; Venkataram, Sandeep; Petrov, Dmitri A; Fisher, Daniel S; Sherlock, Gavin

    2015-03-12

    Evolution of large asexual cell populations underlies ∼30% of deaths worldwide, including those caused by bacteria, fungi, parasites, and cancer. However, the dynamics underlying these evolutionary processes remain poorly understood because they involve many competing beneficial lineages, most of which never rise above extremely low frequencies in the population. To observe these normally hidden evolutionary dynamics, we constructed a sequencing-based ultra high-resolution lineage tracking system in Saccharomyces cerevisiae that allowed us to monitor the relative frequencies of ∼500,000 lineages simultaneously. In contrast to some expectations, we found that the spectrum of fitness effects of beneficial mutations is neither exponential nor monotonic. Early adaptation is a predictable consequence of this spectrum and is strikingly reproducible, but the initial small-effect mutations are soon outcompeted by rarer large-effect mutations that result in variability between replicates. These results suggest that early evolutionary dynamics may be deterministic for a period of time before stochastic effects become important.

  2. High Resolution Spectral Analysis for Irregularly Sampled Helioseismic Data

    Science.gov (United States)

    Seghouani, N.

    2006-11-01

    Astronomical ground based data are very often irregularly sampled due to many factors such as: diurnal effect, weather conditions, etc. The analysis of such data cannot be performed with classical tools (such as periodigram) and new adapted methods are required. After presenting some of these techniques, we will focus on a regularized approach of the spectral analysis problem, which gives very good results in the case of band limited and narrow peaks spectrum. We will also show that with this approach we can achieve high-resolution spectra. Indeed, in classical Fourier analysis, spectral resolution is inversely proportional to the observation time T. Considering the spectral analysis problem as an inverse problem and introducing the “a priori” knowledge of band limited and narrow peak spectrum, this limit (1/T) can be exceeded and thus we can achieve highly resolved spectra, even with irregularly sampled data. This technique will be first applied to relevant simulated data, then to helioseismic data. Additional talk: “Brief description of solar projects in Algiers Observatory” A brief description of all projects developed in our department and that are related to the sun: helioseismology, solar data analysis (pipelines description), solar activity, VLF project, solar astrolabe (for solar diameter measurement), site testing for day-time observations, and the project of solar observatory in the Tamanrasset area.

  3. Small UAV-Acquired, High-resolution, Georeferenced Still Imagery

    Energy Technology Data Exchange (ETDEWEB)

    Ryan Hruska

    2005-09-01

    Currently, small Unmanned Aerial Vehicles (UAVs) are primarily used for capturing and down-linking real-time video. To date, their role as a low-cost airborne platform for capturing high-resolution, georeferenced still imagery has not been fully utilized. On-going work within the Unmanned Vehicle Systems Program at the Idaho National Laboratory (INL) is attempting to exploit this small UAV-acquired, still imagery potential. Initially, a UAV-based still imagery work flow model was developed that includes initial UAV mission planning, sensor selection, UAV/sensor integration, and imagery collection, processing, and analysis. Components to support each stage of the work flow are also being developed. Critical to use of acquired still imagery is the ability to detect changes between images of the same area over time. To enhance the analysts’ change detection ability, a UAV-specific, GIS-based change detection system called SADI or System for Analyzing Differences in Imagery is under development. This paper will discuss the associated challenges and approaches to collecting still imagery with small UAVs. Additionally, specific components of the developed work flow system will be described and graphically illustrated using varied examples of small UAV-acquired still imagery.

  4. A System for High-Resolution Topology Optimization.

    Science.gov (United States)

    Wu, Jun; Dick, Christian; Westermann, Rudiger

    2016-03-01

    A key requirement in 3D fabrication is to generate objects with individual exterior shapes and their interior being optimized to application-specific force constraints and low material consumption. Accomplishing this task is challenging on desktop computers, due to the extreme model resolutions that are required to accurately predict the physical shape properties, requiring memory and computational capacities going beyond what is currently available. Moreover, fabrication-specific constraints need to be considered to enable printability. To address these challenges, we present a scalable system for generating 3D objects using topology optimization, which allows to efficiently evolve the topology of high-resolution solids towards printable and light-weight-high-resistance structures. To achieve this, the system is equipped with a high-performance GPU solver which can efficiently handle models comprising several millions of elements. A minimum thickness constraint is built into the optimization process to automatically enforce printability of the resulting shapes. We further shed light on the question how to incorporate geometric shape constraints, such as symmetry and pattern repetition, in the optimization process. We analyze the performance of the system and demonstrate its potential by a variety of different shapes such as interior structures within closed surfaces, exposed support structures, and surface models.

  5. Improvement of sensitivity in high-resolution Rutherford backscattering spectroscopy.

    Science.gov (United States)

    Hashimoto, H; Nakajima, K; Suzuki, M; Sasakawa, K; Kimura, K

    2011-06-01

    The sensitivity (limit of detection) of high-resolution Rutherford backscattering spectroscopy (HRBS) is mainly determined by the background noise of the spectrometer. There are two major origins of the background noise in HRBS, one is the stray ions scattered from the inner wall of the vacuum chamber of the spectrometer and the other is the dark noise of the microchannel plate (MCP) detector which is commonly used as a focal plane detector of the spectrometer in HRBS. In order to reject the stray ions, several barriers are installed inside the spectrometer and a thin Mylar foil is mounted in front of the detector. The dark noise of the MCP detector is rejected by the coincidence measurement with the secondary electrons emitted from the Mylar foil upon the ion passage. After these improvements, the background noise is reduced by a factor of 200 at a maximum. The detection limit can be improved down to 10 ppm for As in Si at a measurement time of 1 h under ideal conditions. © 2011 American Institute of Physics

  6. Radiation length imaging with high-resolution telescopes

    Science.gov (United States)

    Stolzenberg, U.; Frey, A.; Schwenker, B.; Wieduwilt, P.; Marinas, C.; Lütticke, F.

    2017-02-01

    The construction of low mass vertex detectors with a high level of system integration is of great interest for next generation collider experiments. Radiation length images with a sufficient spatial resolution can be used to measure and disentangle complex radiation length X/X0 profiles and contribute to the understanding of vertex detector systems. Test beam experiments with multi GeV particle beams and high-resolution tracking telescopes provide an opportunity to obtain precise 2D images of the radiation length of thin planar objects. At the heart of the X/X0 imaging is a spatially resolved measurement of the scattering angles of particles traversing the object under study. The main challenges are the alignment of the reference telescope and the calibration of its angular resolution. In order to demonstrate the capabilities of X/X0 imaging, a test beam experiment has been conducted. The devices under test were two mechanical prototype modules of the Belle II vertex detector. A data sample of 100 million tracks at 4 GeV has been collected, which is sufficient to resolve complex material profiles on the 30 μm scale.

  7. Bright Semiconductor Scintillator for High Resolution X-Ray Imaging

    Energy Technology Data Exchange (ETDEWEB)

    Nagarkar, Vivek V.; Gaysinskiy, Valeriy; Ovechkina, Olena E.; Miller, Stuart; Singh, Bipin; Guo, Liang; Irving, Thomas (IIT); (Rad. Monitoring)

    2011-08-16

    We report on a novel approach to produce oxygen-doped zinc telluride (ZnTe:O), a remarkable group II-VI semiconductor scintillator, fabricated in the columnar-structured or polycrystalline forms needed to fulfill the needs of many demanding X-ray and {gamma}-ray imaging applications. ZnTe:O has one of the highest conversion efficiencies among known scintillators, emission around 680 nm (which is ideally suited for CCD sensors), high density of 6.4 g/cm{sup 3}, fast decay time of {approx}1 {micro}s with negligible afterglow, and orders of magnitude higher radiation resistance compared to commonly used scintillators. These properties allow the use of ZnTe:O in numerous applications, including X-ray imaging, nuclear medicine (particularly SPECT), room temperature radioisotope identification, and homeland security. Additionally, ZnTe:O offers distinct advantages for synchrotron-based high resolution imaging due to the absence of atomic absorption edges in the low energy range, which otherwise reduce resolution due to secondary X-ray formations. We have fabricated films of ZnTe:O using a vapor deposition technique that allows large-area structured scintillator fabrication in a time- and cost-efficient manner, and evaluated its performance for small-angle X-ray scattering (SAXS) at an Argonne National Laboratory synchrotron beamline. Details of the fabrication and characterization of the optical, scintillation and imaging properties of the ZnTe:O films are presented in this paper.

  8. A New, Adaptable, Optical High-Resolution 3-Axis Sensor

    Directory of Open Access Journals (Sweden)

    Niels Buchhold

    2017-01-01

    Full Text Available This article presents a new optical, multi-functional, high-resolution 3-axis sensor which serves to navigate and can, for example, replace standard joysticks in medical devices such as electric wheelchairs, surgical robots or medical diagnosis devices. A light source, e.g., a laser diode, is affixed to a movable axis and projects a random geometric shape on an image sensor (CMOS or CCD. The downstream microcontroller’s software identifies the geometric shape’s center, distortion and size, and then calculates x, y, and z coordinates, which can be processed in attached devices. Depending on the image sensor in use (e.g., 6.41 megapixels, the 3-axis sensor features a resolution of 1544 digits from right to left and 1038 digits up and down. Through interpolation, these values rise by a factor of 100. A unique feature is the exact reproducibility (deflection to coordinates and its precise ability to return to its neutral position. Moreover, optical signal processing provides a high level of protection against electromagnetic and radio frequency interference. The sensor is adaptive and adjustable to fit a user’s range of motion (stroke and force. This recommendation aims to optimize sensor systems such as joysticks in medical devices in terms of safety, ease of use, and adaptability.

  9. A high-resolution radio image of a young supernova

    Energy Technology Data Exchange (ETDEWEB)

    Bartel, N.; Rupen, M.P.; Shapiro, I.I. (Harvard-Smithsonian Center for Astrophysics, Cambridge, MA (USA)); Preston, R.A. (Jet Propulsion Lab., Pasadena, CA (USA)); Rius, A. (Universidad Complutense de Madrid (Spain). Inst. de Astronomia y Geodesia)

    1991-03-21

    Supernovae in our own Galaxy are so rare that images of their remnants can show only the late aftermath of an explosion that occurred anything from a few hundred to several tens of thousands of years ago. Young supernovae are seen frequently in other galaxies, but because they are more distant it has not been possible until now to obtain high-resolution images that would reveal details of the explosion and the immediate development of the ejected material. Here we present a very-long-baseline interferometric (VLBI) radio image of the bright supernova 1986J, which occurred in the galaxy NGC891 at a distance of {similar to}12 Mpc. No detailed image of any supernova or remnant has been obtained before so soon after the explosion. Our image shows a shell of emission with jet-like protrusions. Their analysis should advance our understanding of the dynamics of the expanding debris, the dissipation of energy into the surrounding circumstellar medium, and the evolution of the supernova into the remnant. (author).

  10. Development of a high resolution module for PET scanners

    Science.gov (United States)

    Stringhini, G.; Pizzichemi, M.; Ghezzi, A.; Stojkovic, A.; Tavernier, S.; Niknejad, T.; Varela, J.; Paganoni, M.; Auffray, E.

    2017-02-01

    Positron Emission Tomography (PET) scanners require high performances in term of spatial resolution and sensitivity to allow early detection of cancer masses. In small animal and organ dedicated PET scanners the Depth of Interaction (DOI) information has to be obtained to avoid parallax errors and to reconstruct high resolution images. In the whole body PET, the DOI information can be useful to correct for the time jitter of the optical photons along the main axis of the scintillator, improving the time performances. In this work we present the development of PET module designed to reach high performance as compared to the current scanners while keeping the complexity of the system reasonably low. The module presented is based on a 64 LYSO (Lutetium-yttrium oxyorthosilicate) crystals matrix and on a 4×4 MPPC (Multi Pixels Photon Counter) array as detector in a 4 to 1 coupling between the crystals and the detector and a single side readout. The lateral surfaces of the crystals are optically treated to be unpolished. The DOI and the energy resolution of the PET module are presented and a fast method to obtain the DOI calibration is discussed.

  11. Optimized generation of high resolution breast anthropomorphic software phantoms

    Science.gov (United States)

    Pokrajac, David D.; Maidment, Andrew D. A.; Bakic, Predrag R.

    2012-01-01

    Purpose: The authors present an efficient method for generating anthropomorphic software breast phantoms with high spatial resolution. Employing the same region growing principles as in their previous algorithm for breast anatomy simulation, the present method has been optimized for computational complexity to allow for fast generation of the large number of phantoms required in virtual clinical trials of breast imaging. Methods: The new breast anatomy simulation method performs a direct calculation of the Cooper’s ligaments (i.e., the borders between simulated adipose compartments). The calculation corresponds to quadratic decision boundaries of a maximum a posteriori classifier. The method is multiscale due to the use of octree-based recursive partitioning of the phantom volume. The method also provides user-control of the thickness of the simulated Cooper’s ligaments and skin. Results: Using the proposed method, the authors have generated phantoms with voxel size in the range of (25–1000 μm)3/voxel. The power regression of the simulation time as a function of the reciprocal voxel size yielded a log-log slope of 1.95 (compared to a slope of 4.53 of our previous region growing algorithm). Conclusions: A new algorithm for computer simulation of breast anatomy has been proposed that allows for fast generation of high resolution anthropomorphic software phantoms. PMID:22482649

  12. A high resolution PVDF (peizoelectric) film respiration sensor

    Science.gov (United States)

    Nakano, Katsuya; Fujita, Kento; Misaki, Shinya; Fujii, Hiroyuki; Johnston, Robert; Misaki, Yukinori

    2017-07-01

    Sensors used today for contact measurement of a subject's breathing work by measuring the inductance change in some film, piezoelectric or pyro-electric, used in the sensor. However, their use can increase stress and burden for patients because of the close proximity to the body that the sensors must be to operate. They must be applied directly to the patient's body by tape or adhesive paste. To address this problem and reduce subject stress and burden, it was decided to research development of a high resolution breathing sensor that could still function even while placed over the patient's clothes. This was achieved by developing a new PVDF piezoelectric film based sensor with an innovative configuration. Through the use of some simple amplification circuitry and processing the output signal, the high sensitivity breathing sensor developed was determined to be able to accurately measure a person's breathing. Also, due to the high sensitivity of the sensor, heart rate was also detectable revealing the possibility for simultaneous measurement of both breathing and heart rate.

  13. Lynx: A High-Resolution Synthetic Aperture Radar

    Energy Technology Data Exchange (ETDEWEB)

    Doerry, A.W.; Hensley, W.H.; Pace, F.; Stence, J.; Tsunoda, S.I.; Walker, B.C.; Woodring, M.

    1999-03-08

    Lynx is a high resolution, synthetic aperture radar (SAR) that has been designed and built by Sandia National Laboratories in collaboration with General Atomics (GA). Although Lynx may be operated on a wide variety of manned and unmanned platforms, it is primarily intended to be fielded on unmanned aerial vehicles. In particular, it may be operated on the Predator, I-GNAT, or Prowler II platforms manufactured by GA Aeronautical Systems, Inc. The Lynx production weight is less than 120 lb. and has a slant range of 30 km (in 4 mm/hr rain). It has operator selectable resolution and is capable of 0.1 m resolution in spotlight mode and 0.3 m resolution in stripmap mode. In ground moving target indicator mode, the minimum detectable velocity is 6 knots with a minimum target cross-section of 10 dBsm. In coherent change detection mode, Lynx makes registered, complex image comparisons either of 0.1 m resolution (minimum) spotlight images or of 0.3 m resolution (minimum) strip images. The Lynx user interface features a view manager that allows it to pan and zoom like a video camera. Lynx was developed under corporate finding from GA and will be manufactured by GA for both military and commercial applications. The Lynx system architecture will be presented and some of its unique features will be described. Imagery at the finest resolutions in both spotlight and strip modes have been obtained and will also be presented.

  14. CHIRON – A new high resolution spectrometer for CTIO

    Directory of Open Access Journals (Sweden)

    Marcy G.W.

    2011-07-01

    Full Text Available Small telescopes can play an important role in the search for exoplanets because they offer an opportunity for high cadence observations that are not possible with large aperture telescopes. However, there is a shortage of high resolution spectrometers for precision Doppler planet searches. We report on an innovative design for CHIRON, an inexpensive spectrometer that we are building for the 1.5-m telescope at CTIO in Chile. The resolution will be R >80.000, the spectral format spanning 410 to 880 nm. The total throughput of the telescope and spectrometer will be better than 12%, comparable with the efficiency of state-of-the-art spectrometers. The design is driven by the requirements for precision Doppler searches for exoplanets using an iodine cell. The optical layout is a classical echelle with 140 mm beam size. The bench-mounted spectrometer will be fibre-fed followed by an image slicer. An apochromatic refractor is used as the camera. Image quality and throughput of the design are excellent over the full spectral range. Extensive use of commercially available components and avoidance of complicated custom optics are key for quick and resource-efficient implementation.

  15. Extraction and labeling high-resolution images from PDF documents

    Science.gov (United States)

    Chachra, Suchet K.; Xue, Zhiyun; Antani, Sameer; Demner-Fushman, Dina; Thoma, George R.

    2013-12-01

    Accuracy of content-based image retrieval is affected by image resolution among other factors. Higher resolution images enable extraction of image features that more accurately represent the image content. In order to improve the relevance of search results for our biomedical image search engine, Open-I, we have developed techniques to extract and label high-resolution versions of figures from biomedical articles supplied in the PDF format. Open-I uses the open-access subset of biomedical articles from the PubMed Central repository hosted by the National Library of Medicine. Articles are available in XML and in publisher supplied PDF formats. As these PDF documents contain little or no meta-data to identify the embedded images, the task includes labeling images according to their figure number in the article after they have been successfully extracted. For this purpose we use the labeled small size images provided with the XML web version of the article. This paper describes the image extraction process and two alternative approaches to perform image labeling that measure the similarity between two images based upon the image intensity projection on the coordinate axes and similarity based upon the normalized cross-correlation between the intensities of two images. Using image identification based on image intensity projection, we were able to achieve a precision of 92.84% and a recall of 82.18% in labeling of the extracted images.

  16. Morphology of Shatsky Rise oceanic plateau from high resolution bathymetry

    Science.gov (United States)

    Zhang, Jinchang; Sager, William W.; Durkin, William J.

    2017-06-01

    Newly collected, high resolution multi-beam sonar data are combined with previous bathymetry data to produce an improved bathymetric map of Shatsky Rise oceanic plateau. Bathymetry data show that two massifs within Shatsky Rise are immense central volcanoes with gentle flank slopes declining from a central summit. Tamu Massif is a slightly elongated, dome-like volcanic edifice; Ori Massif is square shaped and smaller in area. Several down-to-basin normal faults are observed on the western flank of the massifs but they do not parallel the magnetic lineations, indicating that these faults are probably not related to spreading ridge faulting. Moreover, the faults are observed only on one side of the massifs, which is contrary to expectations from a mechanism of differential subsidence around the massif center. Multi-beam data show many small secondary cones with different shapes and sizes that are widely-distributed on Shatsky Rise massifs, which imply small late-stage magma sources scattered across the surface of the volcanoes in the form of lava flows or explosive volcanism. Erosional channels occur on the flanks of Shatsky Rise volcanoes due to mass wasting and display evidence of down-slope sediment movement. These channels are likely formed by sediments spalling off the edges of summit sediment cap.

  17. A new high resolution tidal model in the arctic ocean

    DEFF Research Database (Denmark)

    Cancet, M.; Andersen, Ole Baltazar; Lyard, F.

    The Arctic Ocean is a challenging region for tidal modeling, because of its complex and not well-documented bathymetry, together combined with the intermittent presence of sea ice and the fact that the in situ tidal observations are rather scarce at such high latitudes. As a consequence, the accu...... for assimilation and validation. This paper presents the performances of this new regional tidal model in the Arctic Ocean, compared to the existing global tidal models.......The Arctic Ocean is a challenging region for tidal modeling, because of its complex and not well-documented bathymetry, together combined with the intermittent presence of sea ice and the fact that the in situ tidal observations are rather scarce at such high latitudes. As a consequence......-growing maritime and industrial activities in this region. NOVELTIS and DTU Space have developed a regional, high-resolution tidal atlas in the Arctic Ocean, in the framework of the CryoSat Plus for Ocean (CP4O) ESA project. In particular, this atlas benefits from the assimilation of the most complete satellite...

  18. A Unitary Anesthetic Binding Site at High Resolution

    Energy Technology Data Exchange (ETDEWEB)

    L Vedula; G Brannigan; N Economou; J Xi; M Hall; R Liu; M Rossi; W Dailey; K Grasty; et. al.

    2011-12-31

    Propofol is the most widely used injectable general anesthetic. Its targets include ligand-gated ion channels such as the GABA{sub A} receptor, but such receptor-channel complexes remain challenging to study at atomic resolution. Until structural biology methods advance to the point of being able to deal with systems such as the GABA{sub A} receptor, it will be necessary to use more tractable surrogates to probe the molecular details of anesthetic recognition. We have previously shown that recognition of inhalational general anesthetics by the model protein apoferritin closely mirrors recognition by more complex and clinically relevant protein targets; here we show that apoferritin also binds propofol and related GABAergic anesthetics, and that the same binding site mediates recognition of both inhalational and injectable anesthetics. Apoferritin binding affinities for a series of propofol analogs were found to be strongly correlated with the ability to potentiate GABA responses at GABA{sub A} receptors, validating this model system for injectable anesthetics. High resolution x-ray crystal structures reveal that, despite the presence of hydrogen bond donors and acceptors, anesthetic recognition is mediated largely by van der Waals forces and the hydrophobic effect. Molecular dynamics simulations indicate that the ligands undergo considerable fluctuations about their equilibrium positions. Finally, apoferritin displays both structural and dynamic responses to anesthetic binding, which may mimic changes elicited by anesthetics in physiologic targets like ion channels.

  19. A Unitary Anesthetic Binding Site at High Resolution

    Energy Technology Data Exchange (ETDEWEB)

    Vedula, L. Sangeetha; Brannigan, Grace; Economou, Nicoleta J.; Xi, Jin; Hall, Michael A.; Liu, Renyu; Rossi, Matthew J.; Dailey, William P.; Grasty, Kimberly C.; Klein, Michael L.; Eckenhoff, Roderic G.; Loll, Patrick J.; (Drexel-MED); (UPENN)

    2009-10-21

    Propofol is the most widely used injectable general anesthetic. Its targets include ligand-gated ion channels such as the GABA{sub A} receptor, but such receptor-channel complexes remain challenging to study at atomic resolution. Until structural biology methods advance to the point of being able to deal with systems such as the GABA{sub A} receptor, it will be necessary to use more tractable surrogates to probe the molecular details of anesthetic recognition. We have previously shown that recognition of inhalational general anesthetics by the model protein apoferritin closely mirrors recognition by more complex and clinically relevant protein targets; here we show that apoferritin also binds propofol and related GABAergic anesthetics, and that the same binding site mediates recognition of both inhalational and injectable anesthetics. Apoferritin binding affinities for a series of propofol analogs were found to be strongly correlated with the ability to potentiate GABA responses at GABA{sub A} receptors, validating this model system for injectable anesthetics. High resolution x-ray crystal structures reveal that, despite the presence of hydrogen bond donors and acceptors, anesthetic recognition is mediated largely by van der Waals forces and the hydrophobic effect. Molecular dynamics simulations indicate that the ligands undergo considerable fluctuations about their equilibrium positions. Finally, apoferritin displays both structural and dynamic responses to anesthetic binding, which may mimic changes elicited by anesthetics in physiologic targets like ion channels.

  20. High resolution fluorescence bio-imaging upconversion nanoparticles in insects.

    Science.gov (United States)

    Alkahtani, Masfer; Chen, Yunyun; Pedraza, Julie J; González, Jorge M; Parkinson, Dilworth Y; Hemmer, Philip R; Liang, Hong

    2017-01-23

    Imaging fluorescent markers with brightness, photostability, and continuous emission with auto fluorescence background suppression in biological samples has always been challenging due to limitations of available and economical techniques. Here we report a new approach, to achieve high contrast imaging inside small and difficult biological systems with special geometry such as fire ants, an important agricultural pest, using a homemade cost-effective optical system. Unlike the commonly used rare-earth doped fluoride nanoparticles, we utilized nanoparticles with a high upconversion efficiency in water. Specifically Y2O3:Er+3,Yb+3 nanoparticles (40-50 nm diameter) were fed to fire ants as food and then a simple illuminating experiment was conducted at 980 nm wavelength at relatively low pump intensity8 kW.cm-2. The locations were further confirmed by X-ray tomography, where most particles aggregated inside the ant's mouth. High resolution, fast, and economical optical imaging system opens the door for studying more complex biological systems.

  1. High-resolution CT findings of varicella-zoster pneumonia

    Energy Technology Data Exchange (ETDEWEB)

    Choo, Hye Jeung; Kim, Kun Il [Busan National Univ. Hospital, Busan (Korea, Republic of); Lee, Ki Nam [College of Medicine, Donga Univ., Busan (Korea, Republic of)

    2003-12-01

    To describe the high-resolution CT findings of varicella-zoster pneumonia. Seven adult patients with clinically and serologically diagnosed varicella-zoster pneumonia underwent HRCT scanning. One had undergone a kidney transplant, and the others were immunocompetent. The HRCT findings were retrospectively analyzed by two radiologists in terms of the presence of a nodule, pneumonia consolidation, ground-glass attenuation and pleural effusion, and with regard to the number, size and distribution of nodules. HRCT findings of varicella pneumonia included nodule (n=7), consolidation (n=3), diffuse ground-glass attenuation (n=1) and pleural effusion (n=1). Nodules were mostly 2-10 mm in size, and multiple (n=6), and zonal predominancy was not apparent. One case in which HRCT demonstrated diffuse ground-glass opacity and slight bilateral pleural effusion involved a patient in whom complications of acute respiratory distress syndrome occured. When HRCT demonstrates the presence of nodules 2-10 mm in size multiple nodules, or nodule surrounded by ground-glass attenuation, or the coalescence of nodules and consolidation is observed in adults with chickenpox, the varicella-zoster pneumonia should be included in the differential diagnosis.

  2. INTRIGOSS: A new Library of High Resolution Synthetic Spectra

    Science.gov (United States)

    Franchini, Mariagrazia; Morossi, Carlo; Di Marcancantonio, Paolo; Chavez, Miguel; GES-Builders

    2018-01-01

    INTRIGOSS (INaf Trieste Grid Of Synthetic Spectra) is a new High Resolution (HiRes) synthetic spectral library designed for studying F, G, and K stars. The library is based on atmosphere models computed with specified individual element abundances via ATLAS12 code. Normalized SPectra (NSP) and surface Flux SPectra (FSP), in the 4800-5400 Å wavelength range, were computed by means of the SPECTRUM code. The synthetic spectra are computed with an atomic and bi-atomic molecular line list including "bona fide" Predicted Lines (PLs) built by tuning loggf to reproduce very high SNR Solar spectrum and the UVES-U580 spectra of five cool giants extracted from the Gaia-ESO survey (GES). The astrophysical gf-values were then assessed by using more than 2000 stars with homogenous and accurate atmosphere parameters and detailed chemical composition from GES. The validity and greater accuracy of INTRIGOSS NSPs and FSPs with respect to other available spectral libraries is discussed. INTRIGOSS will be available on the web and will be a valuable tool for both stellar atmospheric parameters and stellar population studies.

  3. A parallel solution for high resolution histological image analysis.

    Science.gov (United States)

    Bueno, G; González, R; Déniz, O; García-Rojo, M; González-García, J; Fernández-Carrobles, M M; Vállez, N; Salido, J

    2012-10-01

    This paper describes a general methodology for developing parallel image processing algorithms based on message passing for high resolution images (on the order of several Gigabytes). These algorithms have been applied to histological images and must be executed on massively parallel processing architectures. Advances in new technologies for complete slide digitalization in pathology have been combined with developments in biomedical informatics. However, the efficient use of these digital slide systems is still a challenge. The image processing that these slides are subject to is still limited both in terms of data processed and processing methods. The work presented here focuses on the need to design and develop parallel image processing tools capable of obtaining and analyzing the entire gamut of information included in digital slides. Tools have been developed to assist pathologists in image analysis and diagnosis, and they cover low and high-level image processing methods applied to histological images. Code portability, reusability and scalability have been tested by using the following parallel computing architectures: distributed memory with massive parallel processors and two networks, INFINIBAND and Myrinet, composed of 17 and 1024 nodes respectively. The parallel framework proposed is flexible, high performance solution and it shows that the efficient processing of digital microscopic images is possible and may offer important benefits to pathology laboratories. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  4. Quantitative stratigraphy of snow resolved by high-resolution penetrometry

    Science.gov (United States)

    Proksch, Martin; Reuter, Benjamin; Schneebeli, Martin; Löwe, Henning

    2014-05-01

    Precise measurements of snow structural parameters are essential to understand and model snow physical processes. Snow metamorphism, mass and energy balance of snow, radiative properties or the snowpack stability with respect to avalanche formation, all these processes depend on the snow structural parameters and the stratigraphy of the snowpack. However, most snow measurements are limited in spatial and temporal resolution and by extensive measurement times. For this reason, we developed a statistical model to derive three major snow structural parameters, density, correlation length and specific surface area (SSA) solely from a portable, high-resolution penetrometer. We demonstrate the potential of the method by a transect through Alpine snow in the Wannengrat study site, Davos, Switzerland. The two-dimensional plot of the transect reveals the depositional and metamorphic events. The results for the density are compared to independent density measurements from snow profiles. Based on these data, we are able to give a more complete interpretation of the snow stratigraphy and the underlying physical processes.

  5. High-Resolution Rotational Spectroscopy of a Molecular Rotary Motor

    Science.gov (United States)

    Domingos, Sergio R.; Cnossen, Arjen; Perez, Cristobal; Buma, Wybren Jan; Browne, Wesley R.; Feringa, Ben L.; Schnell, Melanie

    2017-06-01

    To develop synthetic molecular motors and machinery that can mimic their biological counterparts has become a stimulating quest in modern synthetic chemistry. Gas phase studies of these simpler synthetic model systems provide the necessary isolated conditions that facilitate the elucidation of their structural intricacies. We report the first high-resolution rotational study of a synthetic molecular rotary motor based on chiral overcrowded alkenes using chirp-pulsed Fourier transform microwave spectroscopy. Rotational constants and quartic centrifugal distortion constants were determined based on a fit using more than two hundred rotational transitions spanning 5≤J≤21 in the 2-4 GHz frequency range. Despite the lack of polar groups, the rotor's asymmetry produces strong a- and b-type rotational transitions arising from a single predominant conformer. Evidence for fragmentation of the rotor allows for unambiguous identification of the isolated rotor components. The experimental spectroscopic parameters of the rotor are compared and discussed against current high-level ab initio and density functional theory methods. Vicario et al. Chem. Commun., 5910-5912 (2005) Brown et al. Rev. Sci. Instrum., 79, 053103 (2008)

  6. Montecarlo simulation for a new high resolution elemental analysis methodology

    Energy Technology Data Exchange (ETDEWEB)

    Figueroa S, Rodolfo; Brusa, Daniel; Riveros, Alberto [Universidad de La Frontera, Temuco (Chile). Facultad de Ingenieria y Administracion

    1996-12-31

    Full text. Spectra generated by binary, ternary and multielement matrixes when irradiated by a variable energy photon beam are simulated by means of a Monte Carlo code. Significative jumps in the counting rate are shown when the photon energy is just over the edge associated to each element, because of the emission of characteristic X rays. For a given associated energy, the net height of these jumps depends mainly on the concentration and of the sample absorption coefficient. The spectra were obtained by a monochromatic energy scan considering all the emitted radiation by the sample in a 2{pi} solid angle, associating a single multichannel spectrometer channel to each incident energy (Multichannel Scaling (MCS) mode). The simulated spectra were made with Monte Carlo simulation software adaptation of the package called PENELOPE (Penetration and Energy Loss of Positrons and Electrons in matter). The results show that it is possible to implement a new high resolution spectroscopy methodology, where a synchrotron would be an ideal source, due to the high intensity and ability to control the energy of the incident beam. The high energy resolution would be determined by the monochromating system and not by the detection system and not by the detection system, which would basicalbe a photon counter. (author)

  7. Understanding reconstructed Dante spectra using high resolution spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    May, M. J., E-mail: may13@llnl.gov; Widmann, K.; Kemp, G. E.; Thorn, D.; Colvin, J. D.; Schneider, M. B.; Moore, A.; Blue, B. E. [L-170 Lawrence Livermore National Laboratory, 7000 East Ave., Livermore, California 94551 (United States); Weaver, J. [Naval Research Laboratory, 4555 Overlook Ave. SW, Washington, DC 20375 (United States)

    2016-11-15

    The Dante is an 18 channel filtered diode array used at the National Ignition Facility (NIF) to measure the spectrally and temporally resolved radiation flux between 50 eV and 20 keV from various targets. The absolute flux is determined from the radiometric calibration of the x-ray diodes, filters, and mirrors and a reconstruction algorithm applied to the recorded voltages from each channel. The reconstructed spectra are very low resolution with features consistent with the instrument response and are not necessarily consistent with the spectral emission features from the plasma. Errors may exist between the reconstructed spectra and the actual emission features due to assumptions in the algorithm. Recently, a high resolution convex crystal spectrometer, VIRGIL, has been installed at NIF with the same line of sight as the Dante. Spectra from L-shell Ag and Xe have been recorded by both VIRGIL and Dante. Comparisons of these two spectroscopic measurements yield insights into the accuracy of the Dante reconstructions.

  8. High Resolution Imaging Spectrometer (HIRIS): Science and Instrument

    Science.gov (United States)

    Goetz, Alexander F. H.; Davis, Curtiss O.

    1991-01-01

    The High Resolution Imaging Spectrometer (HIRIS) is a facility instrument slated for flight on the second of the EOS-A series of platforms. HIRIS is designed to acquire 24-km wide, 30-m pixel images in 192 spectral bands simultaneously in the 0.4-2.45-micrometer wavelength region. With pointing mirrors it can sample any place on Earth, except the poles, every two days. HIRIS operates at the intermediate scale between the human and the global and therefore links studies of Earth surface processes to global monitoring carried out by lower-resolution instruments. So far, over 50 science data products from HIRIS images have been identified in the fields of atmospheric gases, clouds, snow and ice, water, vegetation, and rocks and soils. The key attribute of imaging spectrometry that makes it possible to derive quantitative information from the data is the large number of contiguous spectral bands. Therefore spectrum matching techniques can be applied. Such techniques are not possible with present-day, multispectral scanner data.

  9. Lung findings on high resolution CT in early ankylosing spondylitis

    Energy Technology Data Exchange (ETDEWEB)

    Kiris, Adem E-mail: ademkiris@hotmail.com; Ozgocmen, Salih; Kocakoc, Ercan; Ardicoglu, Ozge; Ogur, Erkin

    2003-07-01

    Objective: Ankylosing spondylitis (AS) is a chronic inflammatory disease mainly affecting the axial skeleton and pulmonary involvement is a well known feature of the disease. The aim of this study was to investigate the pulmonary high resolution computed tomography (HRCT) findings of patients with early AS. The relationship between pulmonary function tests (PFT) and HRCT findings was also determined. Subjects and methods: Twenty-eight patients with AS (mean age 30.8{+-}7.4 and disease duration 7.0{+-}2.6) were included in the study. Patients with a disease duration of >10 years or had other pulmonary diseases were excluded. All patients underwent plain chest radiography (posteroanterior and lateral views), thoracic HRCT and PFT. Results: All chest radiographs were normal and HRCT revealed abnormalities in 18 patients. The most common abnormalities seen on HRCT were mosaic pattern (ten of 28), subpleural nodule (seven of 28) and parenchymal bands (five of 28). Seven of ten patients with mosaic pattern revealed air trapping areas on end expiratory scans. Twelve patients had abnormal PFT and all had restrictive type of involvement. Ten of these 12 patients had abnormal HRCT and the remaining two patients had normal HRCT. On the other hand, eight patients with normal PFT had abnormalities on HRCT. Conclusion: Patients with early AS frequently have abnormalities on HRCT, even though they have normal PFT and chest X-ray. Small airway involvement was found as frequent as interstitial lung disease in early AS.

  10. High Resolution Sensing and Control of Urban Water Networks

    Science.gov (United States)

    Bartos, M. D.; Wong, B. P.; Kerkez, B.

    2016-12-01

    We present a framework to enable high-resolution sensing, modeling, and control of urban watersheds using (i) a distributed sensor network based on low-cost cellular-enabled motes, (ii) hydraulic models powered by a cloud computing infrastructure, and (iii) automated actuation valves that allow infrastructure to be controlled in real time. This platform initiates two major advances. First, we achieve a high density of measurements in urban environments, with an anticipated 40+ sensors over each urban area of interest. In addition to new measurements, we also illustrate the design and evaluation of a "smart" control system for real-world hydraulic networks. This control system improves water quality and mitigates flooding by using real-time hydraulic models to adaptively control releases from retention basins. We evaluate the potential of this platform through two ongoing deployments: (i) a flood monitoring network in the Dallas-Fort Worth metropolitan area that detects and anticipates floods at the level of individual roadways, and (ii) a real-time hydraulic control system in the city of Ann Arbor, MI—soon to be one of the most densely instrumented urban watersheds in the United States. Through these applications, we demonstrate that distributed sensing and control of water infrastructure can improve flash flood predictions, emergency response, and stormwater contaminant mitigation.

  11. Improved design for high resolution electrospray ionization ion mobility spectrometry.

    Science.gov (United States)

    Jafari, M T

    2009-03-15

    An improved design for high resolution electrospray ionization ion mobility spectrometry (ESI-IMS) was developed by making some salient modifications to the IMS cell and its performance was investigated. To enhance desolvation of electrospray droplets at high sample flow rates in this new design, volume of the desolvation region was decreased by reducing its diameter and the entrance position of the desolvation gas was shifted to the end of the desolvation region (near the ion gate). In addition, the ESI source (both needle and counter electrode) was positioned outside of the heating oven of the IMS. This modification made it possible to use the instrument at higher temperatures, and preventing needle clogging in the electrospray process. The ion mobility spectra of different chemical compounds were obtained. The resolving power and resolution of the instrument were increased by about 15-30% relative to previous design. In this work, the baseline separation of the two adjacent ion peaks of morphine and those of codeine was achieved for the first time with resolutions of 1.5 and 1.3, respectively. These four ion peaks were well separated from each other using carbon dioxide (CO(2)) rather than nitrogen as the drift gas. Finally, the analytical parameters obtained for ethion, metalaxyl, and tributylamine indicated the high performance of the instrument for quantitative analysis.

  12. Verification and enhancement high resolution layers 2012 for Bulgaria

    Science.gov (United States)

    Dimitrov, Ventzeslav; Lubenov, Todor

    Production of high-resolution layers (HRL) is a substantial part of the pan-European component of GMES/Copernicus initial operations (GIO) land monitoring service. The focus of this paper is on the results of the implementation of HRL verification and enhancement tasks for Bulgarian territory. For the reference year 2012 five HRL on land cover characteristics were produced by service providers through sophisticated classification of multi-sensor and multi-temporal satellite images: imperviousness, forests, grasslands, wetlands and permanent water bodies. As a result of the verification systematic classification errors were identified relevant to the subsequent enhancement procedure. The verification was carried out through visual inspection of stratified samples in the HRL using reliable reference spatial data sets, checking for commission and omission errors. The applied procedure included three major parts, the first two - obligatory: general overview of data quality, look-and-feel control of critical strata and statistically based quantitative verification. The enhancement task consisted in correcting errors revealed by the verification giving as a result final enhanced HRL products. Stratification schemes, evaluation grades by strata and HRL from look-and-feel verification and accuracy values from statistical verification are presented. Types and quantities of removed mistakes during the enhancement are structured and summarised. Results show that all HRL except the grasslands layer meet the 85% accuracy requirements.

  13. High-resolution Magnetic Resonance Imaging of Moyamoya Disease

    Science.gov (United States)

    Yu, Le-Bao; Zhang, Qian; Shi, Zhi-Yong; Wang, Ming-Qiu; Zhang, Dong

    2015-01-01

    Objective: To introduce the imaging characteristics of moyamoya disease (MMD) using high-resolution magnetic resonance imaging (HR-MRI) and to discuss the role of HR-MRI in differentiating MMD from other intracranial artery diseases, especially intracranial atherosclerotic disease (ICAD). Data Sources: This review was based on the data in articles published between 2005 and 2015, which were obtained from PubMed. The keywords included HR-MRI, MMD, ICAD, and intracranial artery diseases. Study Selection: Articles related to HR-MRI for MMD or other intracranial artery diseases were selected for review. Results: There are differences between the characteristic patterns of HR-MRI in MMD and ICAD. MMD is associated with inward remodeling, smaller outer diameters, concentric occlusive lesions and homogeneous signal intensity, while ICAD is more likely to be associated with outward remodeling, normal outer diameters, eccentric occlusive lesions, and heterogeneous signal intensity. Other intracranial artery diseases, such as dissection and vasculitis, also have distinctive characteristics in HR-MRI. HR-MRI may become a useful tool for the differential diagnosis of MMD in the future. Conclusions: HR-MRI of MMD provides a more in-depth understanding of MMD, and it is helpful in evaluating pathological changes in the vessel wall and in differentiating MMD from other intracranial artery steno-occlusive diseases, particularly ICAD. PMID:26612300

  14. Understanding reconstructed Dante spectra using high resolution spectroscopy

    Science.gov (United States)

    May, M. J.; Weaver, J.; Widmann, K.; Kemp, G. E.; Thorn, D.; Colvin, J. D.; Schneider, M. B.; Moore, A.; Blue, B. E.

    2016-11-01

    The Dante is an 18 channel filtered diode array used at the National Ignition Facility (NIF) to measure the spectrally and temporally resolved radiation flux between 50 eV and 20 keV from various targets. The absolute flux is determined from the radiometric calibration of the x-ray diodes, filters, and mirrors and a reconstruction algorithm applied to the recorded voltages from each channel. The reconstructed spectra are very low resolution with features consistent with the instrument response and are not necessarily consistent with the spectral emission features from the plasma. Errors may exist between the reconstructed spectra and the actual emission features due to assumptions in the algorithm. Recently, a high resolution convex crystal spectrometer, VIRGIL, has been installed at NIF with the same line of sight as the Dante. Spectra from L-shell Ag and Xe have been recorded by both VIRGIL and Dante. Comparisons of these two spectroscopic measurements yield insights into the accuracy of the Dante reconstructions.

  15. Structure recognition from high resolution images of ceramic composites

    Energy Technology Data Exchange (ETDEWEB)

    Ushizima, Daniela; Perciano, Talita; Krishnan, Harinarayan; Loring, Burlen; Bale, Hrishikesh; Parkinson, Dilworth; Sethian, James

    2015-01-05

    Fibers provide exceptional strength-to-weight ratio capabilities when woven into ceramic composites, transforming them into materials with exceptional resistance to high temperature, and high strength combined with improved fracture toughness. Microcracks are inevitable when the material is under strain, which can be imaged using synchrotron X-ray computed micro-tomography (mu-CT) for assessment of material mechanical toughness variation. An important part of this analysis is to recognize fibrillar features. This paper presents algorithms for detecting and quantifying composite cracks and fiber breaks from high-resolution image stacks. First, we propose recognition algorithms to identify the different structures of the composite, including matrix cracks and fibers breaks. Second, we introduce our package F3D for fast filtering of large 3D imagery, implemented in OpenCL to take advantage of graphic cards. Results show that our algorithms automatically identify micro-damage and that the GPU-based implementation introduced here takes minutes, being 17x faster than similar tools on a typical image file.

  16. High-Resolution Displacement Sensor Using a SQUID Array Amplifier

    Science.gov (United States)

    Chui, Talso; Penanen, Konstantin; Barmatz, M.; Paik, Ho Jung

    2004-01-01

    Improvement in the measurement of displacement has profound implications for both exploration technologies and fundamental physics. For planetary exploration, the new SQUID-based capacitive displacement sensor will enable a more sensitive gravity gradiometer for mapping the interior of planets and moons. A new concept of a superfluid clock to be reported by Penanen and Chui at this workshop is also based on a high-resolution displacement sensor. Examples of high-impact physics projects that can benefit from a better displacement sensor are: detection of gravitational waves, test of the equivalence principle, search for the postulated "axion" particle, and test of the inverse square law of gravity. We describe the concept of a new displacement sensor that makes use of a recent development in the Superconducting Quantum Interference Device (SQUID) technology. The SQUID array amplifier, invented by Welty and Martinis (IEEE Trans. Appl. Superconductivity 3, 2605, 1993), has about the same noise as a conventional SQUID; however, it can work at a much higher frequency of up to 5 MHz. We explain how the higher bandwidth can be translated into higher resolution using a bridge-balancing scheme that can simultaneously balance out both the carrier signal at the bridge output and the electrostatic force acting on the test mass.

  17. Optical multichannel analyzer techniques for high resolution optical spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Chao, J.L.

    1980-06-01

    The development of optical multichannel analyzer techniques for UV/VIS spectroscopy is presented. The research focuses on the development of spectroscopic techniques for measuring high resolution spectral lineshape functions from the exciton phosphorescence in H/sub 2/-1,2,4,5-tetrachlorobenzene. It is found that the temperature dependent frequency shifts and widths confirm a theoretical model based on an exchange theory. The exchange of low energy phonon modes which couple with excited state exciton transitions is shown to display the proper temperature dependent behavior. In addition to the techniques for using the optical multichannel analyzer (OMA) to perform low light level target integration, the use of the OMA for capturing spectral information in transient pulsed laser applications is discussed. An OMP data acquisition system developed for real-time signal processng is described. Both hardware and software interfacing considerations for control and data acquisition by a microcomputer are described. The OMA detector is described in terms of the principles behind its photoelectron detection capabilities and its design is compared with other optoelectronic devices.

  18. High-resolution Doppler model of the human gait

    Science.gov (United States)

    Geisheimer, Jonathan L.; Greneker, Eugene F., III; Marshall, William S.

    2002-07-01

    A high resolution Doppler model of the walking human was developed for analyzing the continuous wave (CW) radar gait signature. Data for twenty subjects were collected simultaneously using an infrared motion capture system along with a two channel 10.525 GHz CW radar. The motion capture system recorded three-dimensional coordinates of infrared markers placed on the body. These body marker coordinates were used as inputs to create the theoretical Doppler output using a model constructed in MATLAB. The outputs of the model are the simulated Doppler signals due to each of the major limbs and the thorax. An estimated radar cross section for each part of the body was assigned using the Lund & Browder chart of estimated body surface area. The resultant Doppler model was then compared with the actual recorded Doppler gait signature in the frequency domain using the spectrogram. Comparison of the two sets of data has revealed several identifiable biomechanical features in the radar gait signature due to leg and body motion. The result of the research shows that a wealth of information can be unlocked from the radar gait signature, which may be useful in security and biometric applications.

  19. Symptomatic isolated middle cerebral artery dissection: High resolution MR findings

    Energy Technology Data Exchange (ETDEWEB)

    Byon, Jung Hee; Kwak, Hyo Sung; Chung, Gyung Ho; Hwang, Seung Bae [Dept. of Radiology, Chonbuk National University Medical School, Jeonju (Korea, Republic of)

    2015-11-15

    To perform high-resolution magnetic resonance imaging (HRMRI) and determine clinical features of patients with acute symptomatic middle cerebral artery (MCA) dissection. Thirteen patients with acute symptomatic MCA dissection underwent HRMRI within 3 days after initial clinical onset. They also underwent routine brain MR imaging. HRMRI examinations included time-of-flight MR angiography (MRA), T2-weighted, T1-weighted, proton-density-weighted, and three-dimensional magnetization-prepared rapid acquisition gradient-echo (MPRAGE) sequences. Conventional angiography and MRA were used as reference standard to establish the diagnosis of MCA dissection. The angiographic findings and HRMRI findings such as intimal flap, double lumen, and intramural hematoma were analyzed in this study. All patients presented cerebral ischemia (median National Institutes of Health Stroke Scale score = 4, range = 0-18). String sign was seen on MRA in seven patients. However, double lumen was seen in all patients on HRMRI by intimal flap. High signal lesion on MPRAGE sequences around the dissection lumen due to intramural hematoma was seen in three patients. HRMRI can be used to easily detect the wall structure of MCA such as the intimal flap and double lumen in patients with acute symptomatic MCA dissection. MPRAGE can detect hemorrhage in false lumen of MCA dissection.

  20. Advances in High-Resolution Microscale Impedance Sensors

    Directory of Open Access Journals (Sweden)

    Marco Carminati

    2017-01-01

    Full Text Available Sensors based on impedance transduction have been well consolidated in the industry for decades. Today, the downscaling of the size of sensing elements to micrometric and submicrometric dimensions is enabled by the diffusion of lithographic processes and fostered by the convergence of complementary disciplines such as microelectronics, photonics, biology, electrochemistry, and material science, all focusing on energy and information manipulation at the micro- and nanoscale. Although such a miniaturization trend is pivotal in supporting the pervasiveness of sensors (in the context of mass deployment paradigms such as smart city, home and body monitoring networks, and Internet of Things, it also presents new challenges for the detection electronics, reaching the zeptoFarad domain. In this tutorial review, a selection of examples is illustrated with the purpose of distilling key indications and guidelines for the design of high-resolution impedance readout circuits and sensors. The applications span from biological cells to inertial and ultrasonic MEMS sensors, environmental monitoring, and integrated photonics.

  1. Constrained droplets for high resolution microscopy of protein fibrillization

    Science.gov (United States)

    Posada, David; Tessier, Peter; Hirsa, Amir

    2011-11-01

    The use of constrained droplets (droplets with pinned contact lines on solid surfaces) is proposed here as a method for sample support in optical microscopy studies. Capillarity acts to contain the liquid sample, allowing access for observations in the bulk and at the gas/liquid interface. At the capillary length scale, surface tension forms stable interfaces, virtually immune to gravity and with curvatures that can be adjusted. This is particularly useful when studying the gas/liquid interface and its vicinity under high resolution optical microscopy. Such observations are normally performed using oil immersion objectives which must be positioned within distances only tens of microns from the region of interest. Constrained droplets can also be used at small scales, requiring minute volumes of analyte. The use of the constrained droplet method is demonstrated by studying the aggregation of insulin into amyloid fibrils in the solution and at the gas/liquid interface, where proteins are prone to denaturation and subsequent fibrillization. Such an aggregation process is associated with many neurodegenerative diseases, including Alzhemier's.

  2. Coded aperture subreflector array for high resolution radar imaging

    Science.gov (United States)

    Lynch, Jonathan J.; Herrault, Florian; Kona, Keerti; Virbila, Gabriel; McGuire, Chuck; Wetzel, Mike; Fung, Helen; Prophet, Eric

    2017-05-01

    HRL Laboratories has been developing a new approach for high resolution radar imaging on stationary platforms. High angular resolution is achieved by operating at 235 GHz and using a scalable tile phased array architecture that has the potential to realize thousands of elements at an affordable cost. HRL utilizes aperture coding techniques to minimize the size and complexity of the RF electronics needed for beamforming, and wafer level fabrication and integration allow tiles containing 1024 elements to be manufactured with reasonable costs. This paper describes the results of an initial feasibility study for HRL's Coded Aperture Subreflector Array (CASA) approach for a 1024 element micromachined antenna array with integrated single-bit phase shifters. Two candidate electronic device technologies were evaluated over the 170 - 260 GHz range, GaN HEMT transistors and GaAs Schottky diodes. Array structures utilizing silicon micromachining and die bonding were evaluated for etch and alignment accuracy. Finally, the overall array efficiency was estimated to be about 37% (not including spillover losses) using full wave array simulations and measured device performance, which is a reasonable value at 235 GHz. Based on the measured data we selected GaN HEMT devices operated passively with 0V drain bias due to their extremely low DC power dissipation.

  3. High Resolution Melting (HRM) applied to wine authenticity.

    Science.gov (United States)

    Pereira, Leonor; Gomes, Sónia; Castro, Cláudia; Eiras-Dias, José Eduardo; Brazão, João; Graça, António; Fernandes, José R; Martins-Lopes, Paula

    2017-02-01

    Wine authenticity methods are in increasing demand mainly in Denomination of Origin designations. The DNA-based methodologies are a reliable means of tracking food/wine varietal composition. The main aim of this work was the study of High Resolution Melting (HRM) application as a screening method for must and wine authenticity. Three sample types (leaf, must and wine) were used to validate the three developed HRM assays (Vv1-705bp; Vv2-375bp; and Vv3-119bp). The Vv1 HRM assay was only successful when applied to leaf and must samples. The Vv2 HRM assay successfully amplified all sample types, allowing genotype discrimination based on melting temperature values. The smallest amplicon, Vv3, produced a coincident melting curve shape in all sample types (leaf and wine) with corresponding genotypes. This study presents sensitive, rapid and efficient HRM assays applied for the first time to wine samples suitable for wine authenticity purposes. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Goddard High Resolution Spectrograph SV/GTO Project

    Science.gov (United States)

    Ebbets, Dennis

    1999-03-01

    Contract number NAS5-30433, known at Ball Aerospace as the GHRS SV/GTO project, supported our participation in the post-launch activities of the Goddard High Resolution Spectrograph aboard the Hubble Space Telescope. The period of performance was December 1988 through December 1998. The contract supported the involvement of Dr Dennis Ebbets in the work of the GHRS Investigation Definition Team, and several of the Ball people in the documentation and publication of results. Three main categories of tasks were covered by this contract; in-orbit calibration of the GHRS, guaranteed time observations, and education and public outreach. The nature and accomplishments of these tasks are described in the report. This summary makes many references to publications in the scientific and technical literature. Appendix A is extracted from a complete bibliography, and lists those papers that are directly related to work performed under this GHRS contract. The tasks related to the in-orbit calibration of the GHRS were by far the largest responsibility during the first six years of the project. During this period Dr. Ebbets was responsible for the definition of calibration requirements, design of experiments, preparation of observing proposals, tracking their implementation and execution, and coordinating the analysis and publication of the results. Prior to the launch of HST in 1990 the observing proposals were developed in cooperation with the scientists on the GHRS DDT, engineers at Ball Aerospace, the operations staff at the STScI, and project coordinators at GSFC.

  5. Accuracy Enhancement of Inertial Sensors Utilizing High Resolution Spectral Analysis

    Directory of Open Access Journals (Sweden)

    Michael Korenberg

    2012-08-01

    Full Text Available In both military and civilian applications, the inertial navigation system (INS and the global positioning system (GPS are two complementary technologies that can be integrated to provide reliable positioning and navigation information for land vehicles. The accuracy enhancement of INS sensors and the integration of INS with GPS are the subjects of widespread research. Wavelet de-noising of INS sensors has had limited success in removing the long-term (low-frequency inertial sensor errors. The primary objective of this research is to develop a novel inertial sensor accuracy enhancement technique that can remove both short-term and long-term error components from inertial sensor measurements prior to INS mechanization and INS/GPS integration. A high resolution spectral analysis technique called the fast orthogonal search (FOS algorithm is used to accurately model the low frequency range of the spectrum, which includes the vehicle motion dynamics and inertial sensor errors. FOS models the spectral components with the most energy first and uses an adaptive threshold to stop adding frequency terms when fitting a term does not reduce the mean squared error more than fitting white noise. The proposed method was developed, tested and validated through road test experiments involving both low-end tactical grade and low cost MEMS-based inertial systems. The results demonstrate that in most cases the position accuracy during GPS outages using FOS de-noised data is superior to the position accuracy using wavelet de-noising.

  6. High resolution electron scattering on {sup 96}Zr

    Energy Technology Data Exchange (ETDEWEB)

    Kremer, Christoph; Bassauer, Sergej; Krugmann, Andreas; Krumbholz, Anna Maria; Pietralla, Norbert; Singer, Maxim; Neumann-Cosel, Peter von [Institut fuer Kernphysik, TU Darmstadt (Germany)

    2015-07-01

    The low-energy structure of the nucleus {sup 96}Zr is interesting for numerous reasons - especially the strong octupole correlation leading to an excitation of the prominent 3{sup -}{sub 1} state with the largest known ground-state transition strength (B(E3, 3{sup +}{sub 1} → 0{sup +}{sub 1}) = 57(4) W.u.) of all nuclei. Even though this nucleus is a good testing ground for nuclear structure theories some low-energy observables are known with insufficient precision. Especially the transition strength of low-lying 2{sup +} states, which are important for the identification of mixed-symmetry states, have large uncertainties. Electron scattering at low impulse transfer has been shown to be capable of obtaining these B(E2) values with high precision. A {sup 96}Zr(e,e{sup '}) experiment has recently been performed at the superconducting electron linear accelerator S-DALINAC at Darmstadt using the high-resolution LINTOTT spectrometer. The experiment and preliminary results are presented.

  7. A high-resolution ambient seismic noise model for Europe

    Science.gov (United States)

    Kraft, Toni

    2014-05-01

    measurement precision (i.e. earthquake location), while considering this extremely complex boundary condition. To solve this problem I have developed a high-resolution ambient seismic noise model for Europe. The model is based on land-use data derived from satellite imagery by the EU-project CORINE in a resolution of 100x100m. The the CORINE data consists of several land-use classes, which, besides others, contain: industrial areas, mines, urban fabric, agricultural areas, permanent corps, forests and open spaces. Additionally, open GIS data for highways, and major and minor roads and railway lines were included from the OpenStreetMap project (www.openstreetmap.org). This data was divided into three classes that represent good, intermediate and bad ambient conditions of the corresponding land-use class based on expert judgment. To account for noise propagation away from its source a smoothing operator was applied to individual land-use noise-fields. Finally, the noise-fields were stacked to obtain an European map of ambient noise conditions. A calibration of this map with data of existing seismic stations Europe allowed me to estimate the expected noise level in actual ground motion units for the three ambient noise condition classes of the map. The result is a high-resolution ambient seismic noise map, that allows the network designer to make educated predictions on the expected noise level for arbitrary location in Europe. The ambient noise model was successfully tested in several network optimization projects in Switzerland and surrounding countries and will hopefully be a valuable contribution to improving the data quality of microseismic monitoring networks in Europe.

  8. High Resolution 3D Radar Imaging of Comet Interiors

    Science.gov (United States)

    Asphaug, E. I.; Gim, Y.; Belton, M.; Brophy, J.; Weissman, P. R.; Heggy, E.

    2012-12-01

    Knowing the interiors of comets and other primitive bodies is fundamental to our understanding of how planets formed. We have developed a Discovery-class mission formulation, Comet Radar Explorer (CORE), based on the use of previously flown planetary radar sounding techniques, with the goal of obtaining high resolution 3D images of the interior of a small primitive body. We focus on the Jupiter-Family Comets (JFCs) as these are among the most primitive bodies reachable by spacecraft. Scattered in from far beyond Neptune, they are ultimate targets of a cryogenic sample return mission according to the Decadal Survey. Other suitable targets include primitive NEOs, Main Belt Comets, and Jupiter Trojans. The approach is optimal for small icy bodies ~3-20 km diameter with spin periods faster than about 12 hours, since (a) navigation is relatively easy, (b) radar penetration is global for decameter wavelengths, and (c) repeated overlapping ground tracks are obtained. The science mission can be as short as ~1 month for a fast-rotating JFC. Bodies smaller than ~1 km can be globally imaged, but the navigation solutions are less accurate and the relative resolution is coarse. Larger comets are more interesting, but radar signal is unlikely to be reflected from depths greater than ~10 km. So, JFCs are excellent targets for a variety of reasons. We furthermore focus on the use of Solar Electric Propulsion (SEP) to rendezvous shortly after the comet's perihelion. This approach leaves us with ample power for science operations under dormant conditions beyond ~2-3 AU. This leads to a natural mission approach of distant observation, followed by closer inspection, terminated by a dedicated radar mapping orbit. Radar reflections are obtained from a polar orbit about the icy nucleus, which spins underneath. Echoes are obtained from a sounder operating at dual frequencies 5 and 15 MHz, with 1 and 10 MHz bandwidths respectively. The dense network of echoes is used to obtain global 3D

  9. High-resolution anoscopy in women with cervical neoplasia.

    Science.gov (United States)

    Heráclio, Sandra A; Schettini, Juliana; Oliveira, Micheline L; Souza, Alex Sandro R; Souza, Paulo Roberto E; Amorim, Melania Maria R

    2015-03-01

    To describe high-resolution anoscopy (HRA) findings and compare them with histopathology results. In a cross-sectional, observational study performed between December 2008 and December 2009, women receiving care at a center in Recife, Brazil, after a histopathologic diagnosis of cervical intraepithelial neoplasia or cervical cancer were screened for anal neoplasia by HRA. Patients with anal lesions were divided into groups A (metaplasia and/or human papillomavirus infection) and B (anal intraepithelial neoplasia [AIN]). Patients with squamous cell atypia in group A and all patients in group B underwent histopathologic analysis. Agreement between HRA and histopathology findings was estimated for group B. HRA was done in 324 women, 204 (63.0%) of whom had anal lesions. Overall, 169 cases (82.8%) were classified as group A and 35 (17.2%) as group B. Histopathologic data were obtained for 28 of the 35 group B cases. Histopathology was suggestive of AIN in 19 (67.9%), resulting in a κ coefficient of 0.45 (95% confidence interval [CI] 0.26-0.65; P<0.001). Relative to histopathology, HRA had sensitivity of 57.6% (95% CI 40.8%-72.7%), specificity of 86.1% (95% CI 75.7%-92.5%), positive likelihood ratio of 4.1 (95% CI 3.1-5.5), negative likelihood ratio of 0.5 (95% CI 0.4-0.5), and accuracy of 76.5% (95% CI 67.2%-83.8%). HRA findings can be systematized, reducing the subjectivity of interpretation. Copyright © 2014 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

  10. High-resolution spectroscopic view of planet formation sites

    Science.gov (United States)

    Regály, Zsolt; Kiss, Laszlo; Sándor, Zsolt; Dullemond, Cornelis P.

    2011-11-01

    Theories of planet formation predict the birth of giant planets in the inner, dense, and gas-rich regions of the circumstellar disks around young stars. These are the regions from which strong CO emission is expected. Observations have so far been unable to confirm the presence of planets caught in formation. We have developed a novel method to detect a giant planet still embedded in a circumstellar disk by the distortions of the CO molecular line profiles emerging from the protoplanetary disk's surface. The method is based on the fact that a giant planet significantly perturbs the gas velocity flow in addition to distorting the disk surface density. We have calculated the emerging molecular line profiles by combining hydrodynamical models with semianalytic radiative transfer calculations. Our results have shown that a giant Jupiter-like planet can be detected using contemporary or future high-resolution near-IR spectrographs such as VLT/CRIRES or ELT/METIS. We have also studied the effects of binarity on disk perturbations. The most interesting results have been found for eccentric circumprimary disks in mid-separation binaries, for which the disk eccentricity - detectable from the asymmetric line profiles - arises from the gravitational effects of the companion star. Our detailed simulations shed new light on how to constrain the disk kinematical state as well as its eccentricity profile. Recent findings by independent groups have shown that core-accretion is severely affected by disk eccentricity, hence detection of an eccentric protoplanetary disk in a young binary system would further constrain planet formation theories.

  11. Leaf Area Index Retrieval Using High Resolution Remote Sensing Data

    Directory of Open Access Journals (Sweden)

    Michele Rinaldi

    2010-06-01

    Full Text Available Vegetation indices obtained from remote sensed data can be used to characterize crop canopy on a large scale using a non-destructive method. With the recent launch of the IKONOS satellite, very high spatial resolution (1 meter images are available for the detailed monitoring of ecosystems as well as for precision agriculture. The aim of this study is to evaluate the accuracy of leaf area index (LAI retrieval over agricultural area that can be obtained by empirical relationships between different spectral vegetation indices (VI and LAI measured on three different dates over the spring-summer period of 2008, in the Capitanata plain (Southern Italy. All the VIs used (NDVI, RDVI, WDVI, MSAVI and GEMI were related to the LAI through exponential regression functions, either global or crop-dependent. In the first case, LAI was estimated with comparable accuracies for all VIs employed, with a slightly higher accuracy for GEMI, which determination coefficient achieved the value of 0.697. Whereas the LAI regression functions were calculated separately for each crop, the WDVI, GEMI and RDVI vegetation indices provided the highest determination coefficients with values close to 0.90 for wheat and sugar beet, and with values close to 0.70 for tomatoes. A validation of the models was carried out with a selection of independent sampling data. The validation confirmed that WDVI and GEMI were the VIs that provided the highest LAI retrieval accuracies, with RMSE values of about to 1.1 m2 m-2. The exponential functions, calibrated and validated to calculate LAI from GEMI, were used to derive LAI maps from IKONOS high-resolution remote sensing images with good accuracy. These maps can be used as input variables for crop growth models, obtaining relevant information that can be useful in agricultural management strategies (in particular irrigation and fertilization, as well as in the application of precision farming.

  12. Impact of High Resolution SST Data on Regional Weather Forecasts

    Science.gov (United States)

    Jedlovec, Gary J.; Case, Jonathon; LaFontaine, Frank; Vazquez, Jorge; Mattocks, Craig

    2010-01-01

    Past studies have shown that the use of coarse resolution SST products such as from the real-time global (RTG) SST analysis[1] or other coarse resolution once-a-day products do not properly portray the diurnal variability of fluxes of heat and moisture from the ocean that drive the formation of low level clouds and precipitation over the ocean. For example, the use of high resolution MODIS SST composite [2] to initialize the Advanced Research Weather Research and Forecast (WRF) (ARW) [3] has been shown to improve the prediction of sensible weather parameters in coastal regions [4][5}. In an extend study, [6] compared the MODIS SST composite product to the RTG SST analysis and evaluated forecast differences for a 6 month period from March through August 2007 over the Florida coastal regions. In a comparison to buoy data, they found that that the MODIS SST composites reduced the bias and standard deviation over that of the RTG data. These improvements led to significant changes in the initial and forecasted heat fluxes and the resulting surface temperature fields, wind patterns, and cloud distributions. They also showed that the MODIS composite SST product, produced for the Terra and Aqua satellite overpass times, captured a component of the diurnal cycle in SSTs not represented in the RTG or other one-a-day SST analyses. Failure to properly incorporate these effects in the WRF initialization cycle led to temperature biases in the resulting short term forecasts. The forecast impact was limited in some situations however, due to composite product inaccuracies brought about by data latency during periods of long-term cloud cover. This paper focuses on the forecast impact of an enhanced MODIS/AMSR-E composite SST product designed to reduce inaccuracies due data latency in the MODIS only composite product.

  13. High Resolution X-ray Views of Solar System Objects

    Science.gov (United States)

    Branduardi-Raymont, Graziella

    2011-05-01

    Over the last decade Chandra, and XMM-Newton, have revealed the beauty and multiplicity of X-ray emissions in our solar system: high resolution data, in both spectral and spatial domains, have been crucial in disentangling the physical processes at work. The talk will review the main findings in this area at the boundary between astrophysics and planetary science, and will show how the solar system offers `next door’ examples of widespread astrophysical phenomena. Jupiter shows bright X-ray aurorae, arising from the interactions of local and/or solar wind ions, and electrons, with its powerful magnetic environment: the ions undergo charge exchange with atmospheric neutrals and generate soft X-ray line emission, and the electrons give rise to bremsstrahlung X-rays. Chandra's unparalleled spatial resolution has shown how the X-ray footprints of the electrons in the aurorae coincide with the bright FUV auroral oval, indicating that the same electron population is likely to be at the origin of both emissions. Moreover, Jupiter's disk scatters solar X-rays, displaying a spectrum that closely resembles that of solar flares. Saturn has not revealed X-ray aurorae (yet), but its disk X-ray brightness, like Jupiter's, is strictly correlated with the Sun's X-ray output. A bright X-ray spot has also been resolved by Chandra on the eastern ansa of Saturn's rings, and its spectrum suggests an origin in the fluorescent scattering of solar X-rays on the rings icy particles. Both Mars and Venus have X-ray emitting disks and exospheres, which can be clearly resolved at high spectral and spatial resolution. And the Earth has bright X-ray aurorae that have been targets of Chandra observations. Finally, comets, with their extended neutral comae and extremely line-rich X-ray spectra, are spectacular X-ray sources, and ideal probes of the conditions of the solar wind in the Sun's proximity.

  14. The Singapore high resolution single cell imaging facility

    Science.gov (United States)

    Watt, Frank; Chen, Xiao; Vera, Armin Baysic De; Udalagama, Chammika N. B.; Ren, M.; Kan, Jeroen A. van; Bettiol, Andrew A.

    2011-10-01

    The Centre for Ion Beam Applications, National University of Singapore has recently expanded from three state-of-the-art beam lines to five. Two new beam lines have been constructed: A second generation proton beam writing line, and a high resolution single cell imaging facility. Both systems feature high demagnification lens systems based on compact Oxford Microbeams OM52 lenses, coupled with reduced lens/image distances. The single cell imaging facility is designed around OM52 compact lenses capable of operating in a variety of high demagnification configurations including the spaced Oxford triplet and the double crossover Russian quadruplet. The new facility has design specifications aimed at spatial resolutions below 50 nm, with a variety of techniques including STIM, secondary electron and fluorescence imaging, and an in-built optical and fluorescence microscope for sample imaging, identification and positioning. Preliminary tests using the single space Oxford triplet configuration have indicated a beam spot size of 31 × 39 nm in the horizontal and vertical directions respectively, at beam currents of ∼10,000 protons per second. However, a weakness in the specifications of the electrostatic scanning system has been identified, and a more stable scanning system needs to be implemented before we can fully realize the optimum performance. A single whole fibroblast cell has been scanned using 1.5 MeV protons, and a median fit to the proton transmission energy loss data has shown that proton STIM gives excellent details of the cell structure despite the relatively poor contrast of proton STIM compared with alpha STIM.

  15. A high-resolution global flood hazard model

    Science.gov (United States)

    Sampson, Christopher C.; Smith, Andrew M.; Bates, Paul B.; Neal, Jeffrey C.; Alfieri, Lorenzo; Freer, Jim E.

    2015-09-01

    Floods are a natural hazard that affect communities worldwide, but to date the vast majority of flood hazard research and mapping has been undertaken by wealthy developed nations. As populations and economies have grown across the developing world, so too has demand from governments, businesses, and NGOs for modeled flood hazard data in these data-scarce regions. We identify six key challenges faced when developing a flood hazard model that can be applied globally and present a framework methodology that leverages recent cross-disciplinary advances to tackle each challenge. The model produces return period flood hazard maps at ˜90 m resolution for the whole terrestrial land surface between 56°S and 60°N, and results are validated against high-resolution government flood hazard data sets from the UK and Canada. The global model is shown to capture between two thirds and three quarters of the area determined to be at risk in the benchmark data without generating excessive false positive predictions. When aggregated to ˜1 km, mean absolute error in flooded fraction falls to ˜5%. The full complexity global model contains an automatically parameterized subgrid channel network, and comparison to both a simplified 2-D only variant and an independently developed pan-European model shows the explicit inclusion of channels to be a critical contributor to improved model performance. While careful processing of existing global terrain data sets enables reasonable model performance in urban areas, adoption of forthcoming next-generation global terrain data sets will offer the best prospect for a step-change improvement in model performance.

  16. Utilization of high resolution satellite gravity over the Carlsberg Ridge

    Science.gov (United States)

    Chatterjee, S.; Bhattacharyya, R.; Majumdar, T. J.

    2007-12-01

    The Carlsberg Ridge lies between the equator and the Owen fracture zone. It is the most prominent mid-ocean ridge segment of the western Indian Ocean, which contains a number of earthquake epicenters. Satellite altimetry can be used to infer subsurface geological structures analogous to gravity anomaly maps generated through ship-borne survey. In this study, free-air gravity and its 3D image have been generated over the Carlsberg Ridge using a very high resolution data base, as obtained from Geosat GM, ERS-1, Seasat and TOPEX/POSEIDON altimeter data. As observed in this study, the Carlsberg Ridge shows a slow spreading characteristic with a deep and wide graben (average width ˜15 km). The transform fault spacing confirms variable slow to intermediate characteristics with first and second order discontinuities. The isostatically compensated region of the Carlsberg Ridge could be demarcated with near zero contour values in the free-air gravity anomaly images over and along the Carlsberg Ridge axes and over most of the fracture zone patterns. Few profiles have been generated across the Carlsberg Ridge and the characteristics of slow/intermediate spreading ridge of various orders of discontinuity could be identified. It has also been observed in zero contour image as well as in the characteristics of valley patterns along the ridge from NW to SE that different spreading rates, from slow to intermediate, are occurring in different parts of the Carlsberg ridge. It maintains the morphology of a slow spreading ridge in the NW, where the wide and deep axial valley (˜1.5 3 km) also implies the pattern of a slow spreading ridge. However, a change in the morphology/depth of the axial valley from NW to SE indicates the nature of the Carlsberg Ridge as a slow to intermediate spreading ridge.

  17. Metallic magnetic calorimeters for high resolution X-ray spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Krantz, M.; Hengstler, D.; Geist, J.; Schoetz, C.; Hassel, K.; Hendricks, S.; Keller, M.; Kempf, S.; Gastaldo, L.; Fleischmann, A.; Enss, C. [Heidelberg Univ. (Germany). KIP

    2015-07-01

    We develop microfabricated, energy dispersive particle detector arrays based on metallic magnetic calorimeters (MMCs) for high resolution X-ray spectroscopy to challenge bound-state QED calculations. Our MMCs are operated at about T=30 mK and use a paramagnetic temperature sensor, read-out by a SQUID, to measure the energy deposited by single X-ray photons. We discuss the physics of MMCs, the detector performance and the cryogenic setups for two different detector arrays. We present their microfabrication layouts with focus on challenges like the heatsinking of each pixel of the detector and the overhanging absorbers. The maXs-20 detector is a linear 1x8-pixel array with excellent linearity in its designated energy range up to 20 keV and unsurpassed energy resolution of 1.6 eV for 6 keV x-rays. MaXs-20 operated in a highly portable pulse tube cooled ADR setup has already been used at the EBIT facilities of the MPI-K for new reference measurements of V-like and Ti-like tungsten. The maXs-30 detector currently in development is a 8x8-pixel 2d-array with an active detection area of 16 mm{sup 2} and is designed to detect X-rays up to 50 keV with a designated energy resolution below 5 eV. MaXs-30 will be operated in a cryogen free 3He/4He-dilution refrigerator at the tip of a 40 cm long cold finger at T=20 mK.

  18. The Suzaku High Resolution X-Ray Spectrometer

    Science.gov (United States)

    Kelley, Richard L.; Mitsuda, Kazuhisa; Allen, Christine A.; Arsenovic, Petar; Audley, Michael D.; Bialas, Thomas G.; Boyce, Kevin R.; Boyle, Robert F.; Breon, Susan R.; Brown, Gregory V.; Cottam, Jean; Dipirro, Michael J.; Fujimoto, Ryuichi; Furusho, Tae; Gendreau, Keith C.; Gochar, Gene G.; Gonzalez, Oscar; Hirabayashi, Masayuki; Holt, Stephen S.; Inoue, Hajime; Ishida, Manabu; Ishisaki, Yoshitaka; Jones, Carol S.; Keski-Kuha, Ritva; Kilbourne, Caroline A.; McCammon, Dan; Morita, Umeyo; Moseley, S. Harvey; Mott, Brent; Narasaki, Katsuhiro; Ogawara, Yoshiaki; Ohashi, Takaya; Ota, Naomi; Panek, John S.; Porter, F. Scott; Serlemitsos, Aristides; Shirron, Peter J.; Sneiderman, Gary A.; Szymkowiak, Andrew E.; Takei, Yoh; Tveekrem, June L.; Volz, Stephen M.; Yamamoto, Mikio; Yamasaki, Noriko Y.

    2007-01-01

    The X-Ray Spectrometer (XRS) has been designed to provide the Suzaku Observatory with non-dispersive, high-resolution X-ray spectroscopy. As designed, the instrument covers the energy range 0.3 to 12keV, which encompasses the most diagnostically rich part of the X-ray band. The sensor consists of a 32-channel array of X-ray microcalorimeters, each with an energy resolution of about 6eV. The very low temperature required for operation of the array (60mK) is provided by a four-stage cooling system containing a single-stage adiabatic demagnetization refrigerator, a superfluid-helium cryostat, a solid-neon dewar, and a single-stage, Stirling-cycle cooler. The Suzaku/XRS is the first orbiting X-ray microcalorimeter spectrometer and was designed to last more than three years in orbit. The early verification phase of the mission demonstrated that the instrument worked properly and that the cryogen consumption rate was low enough to ensure a mission lifetime exceeding 3 years. However, the liquid-He cryogen was completely vaporized two weeks after opening the dewar guard vacuum vent. The problem has been traced to inadequate venting of the dewar He and Ne gases out of the spacecraft and into space. In this paper we present the design and ground testing of the XRS instrument, and then describe the in-flight performance. An energy resolution of 6eV was achieved during pre-launch tests and a resolution of 7eV was obtained in orbit. The slight degradation is due to the effects of cosmic rays.

  19. The Singapore high resolution single cell imaging facility

    Energy Technology Data Exchange (ETDEWEB)

    Watt, Frank, E-mail: phywattf@nus.edu.sg [Centre for Ion Beam Applications, Dept. of Physics, National University of Singapore, Science Drive 3, Singapore 117542 (Singapore); Chen, Xiao; Vera, Armin Baysic De; Udalagama, Chammika N.B.; Ren, M.; Kan, Jeroen A van; Bettiol, Andrew A [Centre for Ion Beam Applications, Dept. of Physics, National University of Singapore, Science Drive 3, Singapore 117542 (Singapore)

    2011-10-15

    The Centre for Ion Beam Applications, National University of Singapore has recently expanded from three state-of-the-art beam lines to five. Two new beam lines have been constructed: A second generation proton beam writing line, and a high resolution single cell imaging facility. Both systems feature high demagnification lens systems based on compact Oxford Microbeams OM52 lenses, coupled with reduced lens/image distances. The single cell imaging facility is designed around OM52 compact lenses capable of operating in a variety of high demagnification configurations including the spaced Oxford triplet and the double crossover Russian quadruplet. The new facility has design specifications aimed at spatial resolutions below 50 nm, with a variety of techniques including STIM, secondary electron and fluorescence imaging, and an in-built optical and fluorescence microscope for sample imaging, identification and positioning. Preliminary tests using the single space Oxford triplet configuration have indicated a beam spot size of 31 x 39 nm in the horizontal and vertical directions respectively, at beam currents of {approx}10,000 protons per second. However, a weakness in the specifications of the electrostatic scanning system has been identified, and a more stable scanning system needs to be implemented before we can fully realize the optimum performance. A single whole fibroblast cell has been scanned using 1.5 MeV protons, and a median fit to the proton transmission energy loss data has shown that proton STIM gives excellent details of the cell structure despite the relatively poor contrast of proton STIM compared with alpha STIM.

  20. High-resolution mapping of motor vehicle carbon dioxide emissions

    Science.gov (United States)

    McDonald, Brian C.; McBride, Zoe C.; Martin, Elliot W.; Harley, Robert A.

    2014-05-01

    A fuel-based inventory for vehicle emissions is presented for carbon dioxide (CO2) and mapped at various spatial resolutions (10 km, 4 km, 1 km, and 500 m) using fuel sales and traffic count data. The mapping is done separately for gasoline-powered vehicles and heavy-duty diesel trucks. Emission estimates from this study are compared with the Emissions Database for Global Atmospheric Research (EDGAR) and VULCAN. All three inventories agree at the national level within 5%. EDGAR uses road density as a surrogate to apportion vehicle emissions, which leads to 20-80% overestimates of on-road CO2 emissions in the largest U.S. cities. High-resolution emission maps are presented for Los Angeles, New York City, San Francisco-San Jose, Houston, and Dallas-Fort Worth. Sharp emission gradients that exist near major highways are not apparent when emissions are mapped at 10 km resolution. High CO2 emission fluxes over highways become apparent at grid resolutions of 1 km and finer. Temporal variations in vehicle emissions are characterized using extensive day- and time-specific traffic count data and are described over diurnal, day of week, and seasonal time scales. Clear differences are observed when comparing light- and heavy-duty vehicle traffic patterns and comparing urban and rural areas. Decadal emission trends were analyzed from 2000 to 2007 when traffic volumes were increasing and a more recent period (2007-2010) when traffic volumes declined due to recession. We found large nonuniform changes in on-road CO2 emissions over a period of 5 years, highlighting the importance of timely updates to motor vehicle emission inventories.

  1. Improved automatic optic nerve radius estimation from high resolution MRI

    Science.gov (United States)

    Harrigan, Robert L.; Smith, Alex K.; Mawn, Louise A.; Smith, Seth A.; Landman, Bennett A.

    2017-02-01

    The optic nerve (ON) is a vital structure in the human visual system and transports all visual information from the retina to the cortex for higher order processing. Due to the lack of redundancy in the visual pathway, measures of ON damage have been shown to correlate well with visual deficits. These measures are typically taken at an arbitrary anatomically defined point along the nerve and do not characterize changes along the length of the ON. We propose a fully automated, three-dimensionally consistent technique building upon a previous independent slice-wise technique to estimate the radius of the ON and surrounding cerebrospinal fluid (CSF) on high-resolution heavily T2-weighted isotropic MRI. We show that by constraining results to be three-dimensionally consistent this technique produces more anatomically viable results. We compare this technique with the previously published slice-wise technique using a short-term reproducibility data set, 10 subjects, follow-up <1 month, and show that the new method is more reproducible in the center of the ON. The center of the ON contains the most accurate imaging because it lacks confounders such as motion and frontal lobe interference. Long-term reproducibility, 5 subjects, follow-up of approximately 11 months, is also investigated with this new technique and shown to be similar to short-term reproducibility, indicating that the ON does not change substantially within 11 months. The increased accuracy of this new technique provides increased power when searching for anatomical changes in ON size amongst patient populations.

  2. High resolution functional photoacoustic tomography of breast cancer

    Energy Technology Data Exchange (ETDEWEB)

    Li, Xiaoqi; Yao, Lei; Xi, Lei; Jiang, Huabei, E-mail: hjiang@bme.ufl.edu [Department of Biomedical Engineering, University of Florida, Gainesville, Florida 32611 (United States); Heldermon, Coy D. [Department of Medicine, University of Florida, Gainesville, Florida 32611 (United States)

    2015-09-15

    Purpose: To evaluate the feasibility of functional photoacoustic tomography (fPAT) for high resolution detection and characterization of breast cancer and to demonstrate for the first time quantitative hemoglobin concentration and oxygen saturation images of breasts that were formed with model-based reconstruction of tomographic photoacoustic data. Methods: The study was HIPAA compliant and was approved by the university institutional review board. Written informed consents were obtained from all the participants. Ten cases, including six cancer and four healthy (mean age = 50 yr; age range = 41–66 yr), were examined. Functional images of breast tissue including absolute total hemoglobin concentration (Hb{sub T}) and oxygen saturation (StO{sub 2}%) were obtained by fPAT and cross validated with magnetic resonance imaging (MRI) readings and/or histopathology. Results: Hb{sub T} and StO{sub 2}% maps from all six pathology-confirmed cancer cases (60%) show clear detection of tumor, while MR images indicate clear detection of tumor for five of six cancer cases; one small tumor was read as near-complete-resolution by MRI. The average Hb{sub T} and StO{sub 2}% value of suspicious lesion area for the cancer cases was 61.6 ± 18.9 μM/l and 67.5% ± 5.2% compared to 25.6 ± 7.4 μM/l and 65.2% ± 3.8% for background normal tissue. Conclusions: fPAT has the potential to be a significant add-on in breast cancer detection and characterization as it provides submillimeter resolution functional images of breast lesions.

  3. Roads Data Conflation Using Update High Resolution Satellite Images

    Science.gov (United States)

    Abdollahi, A.; Riyahi Bakhtiari, H. R.

    2017-11-01

    Urbanization, industrialization and modernization are rapidly growing in developing countries. New industrial cities, with all the problems brought on by rapid population growth, need infrastructure to support the growth. This has led to the expansion and development of the road network. A great deal of road network data has made by using traditional methods in the past years. Over time, a large amount of descriptive information has assigned to these map data, but their geometric accuracy and precision is not appropriate to today's need. In this regard, the improvement of the geometric accuracy of road network data by preserving the descriptive data attributed to them and updating of the existing geo databases is necessary. Due to the size and extent of the country, updating the road network maps using traditional methods is time consuming and costly. Conversely, using remote sensing technology and geographic information systems can reduce costs, save time and increase accuracy and speed. With increasing the availability of high resolution satellite imagery and geospatial datasets there is an urgent need to combine geographic information from overlapping sources to retain accurate data, minimize redundancy, and reconcile data conflicts. In this research, an innovative method for a vector-to-imagery conflation by integrating several image-based and vector-based algorithms presented. The SVM method for image classification and Level Set method used to extract the road the different types of road intersections extracted from imagery using morphological operators. For matching the extracted points and to find the corresponding points, matching function which uses the nearest neighborhood method was applied. Finally, after identifying the matching points rubber-sheeting method used to align two datasets. Two residual and RMSE criteria used to evaluate accuracy. The results demonstrated excellent performance. The average root-mean-square error decreased from 11.8 to 4.1 m.

  4. High-resolution subsurface water-ice distributions on Mars.

    Science.gov (United States)

    Bandfield, Joshua L

    2007-05-03

    Theoretical models indicate that water ice is stable in the shallow subsurface (depths of Mars at high latitudes. These models have been mainly supported by the observed presence of large concentrations of hydrogen detected by the Gamma Ray Spectrometer suite of instruments on the Mars Odyssey spacecraft. The models and measurements are consistent with a water-ice table that steadily increases in depth with decreasing latitude. More detailed modelling has predicted that the depth at which water ice is stable can be highly variable, owing to local surface heterogeneities such as rocks and slopes, and the thermal inertia of the ground cover. Measurements have, however, been limited to the footprint (several hundred kilometres) of the Gamma Ray Spectrometer suite, preventing the observations from documenting more detailed water-ice distributions. Here I show that by observing the seasonal temperature response of the martian surface with the Thermal Emission Imaging System on the Mars Odyssey spacecraft, it is possible to observe such heterogeneities at subkilometre scale. These observations show significant regional and local water-ice depth variability, and, in some cases, support distributions in the subsurface predicted by atmospheric exchange and vapour diffusion models. The presence of water ice where it follows the depth of stability under current climatic conditions implies an active martian water cycle that responds to orbit-driven climate cycles. Several regions also have apparent deviations from the theoretical stability level, indicating that additional factors influence the ice-table depth. The high-resolution measurements show that the depth to the water-ice table is highly variable within the potential Phoenix spacecraft landing ellipses, and is likely to be variable at scales that may be sampled by the spacecraft.

  5. A high-resolution global flood hazard model.

    Science.gov (United States)

    Sampson, Christopher C; Smith, Andrew M; Bates, Paul D; Neal, Jeffrey C; Alfieri, Lorenzo; Freer, Jim E

    2015-09-01

    Floods are a natural hazard that affect communities worldwide, but to date the vast majority of flood hazard research and mapping has been undertaken by wealthy developed nations. As populations and economies have grown across the developing world, so too has demand from governments, businesses, and NGOs for modeled flood hazard data in these data-scarce regions. We identify six key challenges faced when developing a flood hazard model that can be applied globally and present a framework methodology that leverages recent cross-disciplinary advances to tackle each challenge. The model produces return period flood hazard maps at ∼90 m resolution for the whole terrestrial land surface between 56°S and 60°N, and results are validated against high-resolution government flood hazard data sets from the UK and Canada. The global model is shown to capture between two thirds and three quarters of the area determined to be at risk in the benchmark data without generating excessive false positive predictions. When aggregated to ∼1 km, mean absolute error in flooded fraction falls to ∼5%. The full complexity global model contains an automatically parameterized subgrid channel network, and comparison to both a simplified 2-D only variant and an independently developed pan-European model shows the explicit inclusion of channels to be a critical contributor to improved model performance. While careful processing of existing global terrain data sets enables reasonable model performance in urban areas, adoption of forthcoming next-generation global terrain data sets will offer the best prospect for a step-change improvement in model performance.

  6. High Resolution Helium Ion Scanning Microscopy of the Rat Kidney

    Science.gov (United States)

    Rice, William L.; Van Hoek, Alfred N.; Păunescu, Teodor G.; Huynh, Chuong; Goetze, Bernhard; Singh, Bipin; Scipioni, Larry; Stern, Lewis A.; Brown, Dennis

    2013-01-01

    Helium ion scanning microscopy is a novel imaging technology with the potential to provide sub-nanometer resolution images of uncoated biological tissues. So far, however, it has been used mainly in materials science applications. Here, we took advantage of helium ion microscopy to explore the epithelium of the rat kidney with unsurpassed image quality and detail. In addition, we evaluated different tissue preparation methods for their ability to preserve tissue architecture. We found that high contrast, high resolution imaging of the renal tubule surface is possible with a relatively simple processing procedure that consists of transcardial perfusion with aldehyde fixatives, vibratome tissue sectioning, tissue dehydration with graded methanol solutions and careful critical point drying. Coupled with the helium ion system, fine details such as membrane texture and membranous nanoprojections on the glomerular podocytes were visualized, and pores within the filtration slit diaphragm could be seen in much greater detail than in previous scanning EM studies. In the collecting duct, the extensive and striking apical microplicae of the intercalated cells were imaged without the shrunken or distorted appearance that is typical with conventional sample processing and scanning electron microscopy. Membrane depressions visible on principal cells suggest possible endo- or exocytotic events, and central cilia on these cells were imaged with remarkable preservation and clarity. We also demonstrate the use of colloidal gold probes for highlighting specific cell-surface proteins and find that 15 nm gold labels are practical and easily distinguishable, indicating that external labels of various sizes can be used to detect multiple targets in the same tissue. We conclude that this technology represents a technical breakthrough in imaging the topographical ultrastructure of animal tissues. Its use in future studies should allow the study of fine cellular details and provide

  7. B stars seen at high resolution by XMM-Newton

    Science.gov (United States)

    Cazorla, Constantin; Nazé, Yaël

    2017-12-01

    We report on the properties of 11 early B stars observed with gratings on board XMM-Newton and Chandra, thereby doubling the number of B stars analysed at high resolution. The spectra typically appear soft, with temperatures of 0.2-0.6 keV, and moderately bright (log [LX/LBOL] -7) with lower values for later type stars. In line with previous studies, we also find an absence of circumstellar absorption, negligible line broadening, no line shift, and formation radii in the range 2-7 R⋆. From the X-ray brightnesses, we derived the hot mass-loss rate for each of our targets and compared these values to predictions or values derived in the optical domain: in some cases, the hot fraction of the wind can be non-negligible. The derived X-ray abundances were compared to values obtained from the optical data, with a fair agreement found between them. Finally, half of the sample presents temporal variations, either in the long-term, short-term, or both. In particular, HD 44743 is found to be the second example of an X-ray pulsator, and we detect a flare-like activity in the binary HD 79351, which also displays a high-energy tail and one of the brightest X-ray emissions in the sample. Based on observations collected with the ESA science mission XMM-Newton, an ESA science mission with instruments and contributions directly funded by ESA member states and the USA (NASA).

  8. Decadal prediction skill using a high-resolution climate model

    Science.gov (United States)

    Monerie, Paul-Arthur; Coquart, Laure; Maisonnave, Éric; Moine, Marie-Pierre; Terray, Laurent; Valcke, Sophie

    2017-11-01

    The ability of a high-resolution coupled atmosphere-ocean general circulation model (with a horizontal resolution of a quarter of a degree in the ocean and of about 0.5° in the atmosphere) to predict the annual means of temperature, precipitation, sea-ice volume and extent is assessed based on initialized hindcasts over the 1993-2009 period. Significant skill in predicting sea surface temperatures is obtained, especially over the North Atlantic, the tropical Atlantic and the Indian Ocean. The Sea Ice Extent and volume are also reasonably predicted in winter (March) and summer (September). The model skill is mainly due to the external forcing associated with well-mixed greenhouse gases. A decrease in the global warming rate associated with a negative phase of the Pacific Decadal Oscillation is simulated by the model over a suite of 10-year periods when initialized from starting dates between 1999 and 2003. The model ability to predict regional change is investigated by focusing on the mid-90's Atlantic Ocean subpolar gyre warming. The model simulates the North Atlantic warming associated with a meridional heat transport increase, a strengthening of the North Atlantic current and a deepening of the mixed layer over the Labrador Sea. The atmosphere plays a role in the warming through a modulation of the North Atlantic Oscillation: a negative sea level pressure anomaly, located south of the subpolar gyre is associated with a wind speed decrease over the subpolar gyre. This leads to a reduced oceanic heat-loss and favors a northward displacement of anomalously warm and salty subtropical water that both concur to the subpolar gyre warming. We finally conclude that the subpolar gyre warming is mainly triggered by ocean dynamics with a possible contribution of atmospheric circulation favoring its persistence.

  9. High-Resolution Imaging of Asteroids/Satellites with AO

    Science.gov (United States)

    Merline, William

    2012-02-01

    We propose to make high-resolution observations of asteroids using AO, to measure size, shape, and pole position (spin vectors), and/or to search for satellites. We have demonstrated that AO imaging allows determination of the pole/dimensions in 1 or 2 nights on a single target, rather than the years of observations with lightcurve inversion techniques that only yield poles and axial ratios, not true dimensions. Our new technique (KOALA) combines AO imaging with lightcurve and occultation data for optimum size/shape determinations. We request that LGS be available for faint targets, but using NGS AO, we will measure several large and intermediate asteroids that are favorably placed in spring/summer of 2012 for size/shape/pole. Accurately determining the volume from the often-irregular shape allows us to derive densities to much greater precision in cases where the mass is known, e.g., from the presence of a satellite. We will search several d! ozen asteroids for the presence of satellites, particularly in under-studied populations, particularly NEOs (we have recently achieved the first-ever optical image of an NEO binary [Merline et al. 2008b, IAUC 8977]). Satellites provide a real-life lab for testing collisional models. We will search for satellites around special objects at the request of lightcurve observers, and we will make a search for debris in the vicinity of Pluto, in support of the New Horizons mission. Our shape/size work requires observations over most of a full rotation period (typically several hours).

  10. High Resolution Modelling of Crop Response to Climate Change

    Science.gov (United States)

    Mirmasoudi, S. S.; Byrne, J. M.; MacDonald, R. J.; Lewis, D.

    2014-12-01

    Crop production is one of the most vulnerable sectors to climatic variability and change. Increasing atmospheric CO2 concentration and other greenhouse gases are causing increases in global temperature. In western North America, water supply is largely derived from mountain snowmelt. Climate change will have a significant impact on mountain snowpack and subsequently, the snow-derived water supply. This will strain water supplies and increase water demand in areas with substantial irrigation agriculture. Increasing temperatures may create heat stress for some crops regardless of soil water supply, and increasing surface O3 and other pollutants may damage crops and ecosystems. CO2 fertilization may or may not be an advantage in future. This work is part of a larger study that will address a series of questions based on a range of future climate scenarios for several watersheds in western North America. The key questions are: (1) how will snowmelt and rainfall runoff vary in future; (2) how will seasonal and inter-annual soil water supply vary, and how might that impacts food supplies; (3) how might heat stress impact (some) crops even with adequate soil water; (4) will CO2 fertilization alter crop yields; and (5) will pollution loads, particularly O3, cause meaningful changes to crop yields? The Generate Earth Systems Science (GENESYS) Spatial Hydrometeorological Model is an innovative, efficient, high-resolution model designed to assess climate driven changes in mountain snowpack derived water supplies. We will link GENESYS to the CROPWAT crop model system to assess climate driven changes in water requirement and associated crop productivity for a range of future climate scenarios. Literature bases studies will be utilised to develop approximate crop response functions for heat stress, CO2 fertilization and for O3 damages. The overall objective is to create modeling systems that allows meaningful assessment of agricultural productivity at a watershed scale under a

  11. Accelerated high-resolution photoacoustic tomography via compressed sensing.

    Science.gov (United States)

    Arridge, Simon; Beard, Paul; Betcke, Marta; Cox, Ben; Huynh, Nam; Lucka, Felix; Ogunlade, Olumide; Zhang, Edward

    2016-12-21

    Current 3D photoacoustic tomography (PAT) systems offer either high image quality or high frame rates but are not able to deliver high spatial and temporal resolution simultaneously, which limits their ability to image dynamic processes in living tissue (4D PAT). A particular example is the planar Fabry-Pérot (FP) photoacoustic scanner, which yields high-resolution 3D images but takes several minutes to sequentially map the incident photoacoustic field on the 2D sensor plane, point-by-point. However, as the spatio-temporal complexity of many absorbing tissue structures is rather low, the data recorded in such a conventional, regularly sampled fashion is often highly redundant. We demonstrate that combining model-based, variational image reconstruction methods using spatial sparsity constraints with the development of novel PAT acquisition systems capable of sub-sampling the acoustic wave field can dramatically increase the acquisition speed while maintaining a good spatial resolution: first, we describe and model two general spatial sub-sampling schemes. Then, we discuss how to implement them using the FP interferometer and demonstrate the potential of these novel compressed sensing PAT devices through simulated data from a realistic numerical phantom and through measured data from a dynamic experimental phantom as well as from in vivo experiments. Our results show that images with good spatial resolution and contrast can be obtained from highly sub-sampled PAT data if variational image reconstruction techniques that describe the tissues structures with suitable sparsity-constraints are used. In particular, we examine the use of total variation (TV) regularization enhanced by Bregman iterations. These novel reconstruction strategies offer new opportunities to dramatically increase the acquisition speed of photoacoustic scanners that employ point-by-point sequential scanning as well as reducing the channel count of parallelized schemes that use detector arrays.

  12. Accelerated high-resolution photoacoustic tomography via compressed sensing

    Science.gov (United States)

    Arridge, Simon; Beard, Paul; Betcke, Marta; Cox, Ben; Huynh, Nam; Lucka, Felix; Ogunlade, Olumide; Zhang, Edward

    2016-12-01

    Current 3D photoacoustic tomography (PAT) systems offer either high image quality or high frame rates but are not able to deliver high spatial and temporal resolution simultaneously, which limits their ability to image dynamic processes in living tissue (4D PAT). A particular example is the planar Fabry-Pérot (FP) photoacoustic scanner, which yields high-resolution 3D images but takes several minutes to sequentially map the incident photoacoustic field on the 2D sensor plane, point-by-point. However, as the spatio-temporal complexity of many absorbing tissue structures is rather low, the data recorded in such a conventional, regularly sampled fashion is often highly redundant. We demonstrate that combining model-based, variational image reconstruction methods using spatial sparsity constraints with the development of novel PAT acquisition systems capable of sub-sampling the acoustic wave field can dramatically increase the acquisition speed while maintaining a good spatial resolution: first, we describe and model two general spatial sub-sampling schemes. Then, we discuss how to implement them using the FP interferometer and demonstrate the potential of these novel compressed sensing PAT devices through simulated data from a realistic numerical phantom and through measured data from a dynamic experimental phantom as well as from in vivo experiments. Our results show that images with good spatial resolution and contrast can be obtained from highly sub-sampled PAT data if variational image reconstruction techniques that describe the tissues structures with suitable sparsity-constraints are used. In particular, we examine the use of total variation (TV) regularization enhanced by Bregman iterations. These novel reconstruction strategies offer new opportunities to dramatically increase the acquisition speed of photoacoustic scanners that employ point-by-point sequential scanning as well as reducing the channel count of parallelized schemes that use detector arrays.

  13. MULTIPULSE - high resolution and high power in one TDEM system

    Science.gov (United States)

    Chen, Tianyou; Hodges, Greg; Miles, Philip

    2015-09-01

    An airborne time domain electromagnetic (TEM) system with high resolution and great depth of exploration is desired for geological mapping as well as for mineral exploration. The MULTIPULSE technology enables an airborne TEM system to transmit a high power pulse (a half-sine, for instance) and one or multiple low power pulse(s) (trapezoid or square) within a half-cycle. The high power pulse ensures good depth of exploration and the low power pulse allows a fast transmitter current turn off and earlier off-time measurement thus providing higher frequency signals, which allows higher near-surface resolution and better sensitivity to weak conductors. The power spectrum of the MULTIPULSE waveform comprising a half-sine and a trapezoid pulse clearly shows increased power in the higher frequency range (> ~2.3 kHz) compared to that of a single half-sine waveform. The addition of the low power trapezoid pulse extends the range of the sensitivity 10-fold towards the weak conductors, expanding the geological conductivity range of a system and increasing the scope of its applications. The MULTIPULSE technology can be applied to standard single-pulse airborne TEM systems on both helicopter and fixed-wing. We field tested the HELITEM MULTIPULSE system over a wire-loop in Iroquois Falls, demonstrating the different sensitivity of the high and low power pulses to the overburden and the wire-loop. We also tested both HELITEM and GEOTEM MULTIPULSE systems over a layered oil sand geologic setting in Fort McMurray, Alberta, Canada. The results show comparable shallow geologic resolution of the MULTIPULSE to that of the RESOLVE system while maintaining superior depth of exploration, confirming the increased geological conductivity range of a system employing MULTIPULSE compared to the standard single-pulse systems.

  14. High-Resolution Maps of Mouse Reference Populations

    Directory of Open Access Journals (Sweden)

    Petr Simecek

    2017-10-01

    Full Text Available Genetic reference panels are widely used to map complex, quantitative traits in model organisms. We have generated new high-resolution genetic maps of 259 mouse inbred strains from recombinant inbred strain panels (C57BL/6J × DBA/2J, ILS/IbgTejJ × ISS/IbgTejJ, and C57BL/6J × A/J and chromosome substitution strain panels (C57BL/6J-Chr#, C57BL/6J-Chr#, and C57BL/6J-Chr#. We genotyped all samples using the Affymetrix Mouse Diversity Array with an average intermarker spacing of 4.3 kb. The new genetic maps provide increased precision in the localization of recombination breakpoints compared to the previous maps. Although the strains were presumed to be fully inbred, we found residual heterozygosity in 40% of individual mice from five of the six panels. We also identified de novo deletions and duplications, in homozygous or heterozygous state, ranging in size from 21 kb to 8.4 Mb. Almost two-thirds (46 out of 76 of these deletions overlap exons of protein coding genes and may have phenotypic consequences. Twenty-nine putative gene conversions were identified in the chromosome substitution strains. We find that gene conversions are more likely to occur in regions where the homologous chromosomes are more similar. The raw genotyping data and genetic maps of these strain panels are available at http://churchill-lab.jax.org/website/MDA.

  15. A high resolution hand-held focused beam profiler

    Science.gov (United States)

    Zapata-Farfan, J.; Garduño-Mejía, J.; Rosete-Aguilar, M.; Ascanio, G.; Román-Moreno, C. J.

    2017-05-01

    The shape of a beam is important in any laser application and depending on the final implementation, there exists a preferred one which is defined by the irradiance distribution.1 The energy distribution (or laser beam profile) is an important parameter in a focused beam, for instance, in laser cut industry, where the beam shape determines the quality of the cut. In terms of alignment and focusing, the energy distribution also plays an important role since the system must be configured in order to reduce the aberration effects and achieve the highest intensity. Nowadays a beam profiler is used in both industry and research laboratories with the aim to characterize laser beams used in free-space communications, focusing and welding, among other systems. The purpose of the profile analyzers is to know the main parameters of the beam, to control its characteristics as uniformity, shape and beam size as a guide to align the focusing system. In this work is presented a high resolution hand-held and compact design of a beam profiler capable to measure at the focal plane, with covered range from 400 nm to 1000 nm. The detection is reached with a CMOS sensor sized in 3673.6 μm x 2738.4 μm which acquire a snap shot of the previously attenuated focused beam to avoid the sensor damage, the result is an image of beam intensity distribution, which is digitally processed with a RaspberryTMmodule gathering significant parameters such as beam waist, centroid, uniformity and also some aberrations. The profiler resolution is 1.4 μm and was probed and validated in three different focusing systems. The spot sizes measurements were compared with the Foucault knife-edge test.

  16. High-resolution ultrasonography of xenografted domestic cat ovarian cortex.

    Science.gov (United States)

    Fassbender, Mirja; Hildebrandt, Thomas Bernd; Paris, Monica Christina Johanna; Colenbrander, Ben; Jewgenow, Katarina

    2007-10-01

    Transplantation of ovarian tissue has high potential for female gamete conservation. However, optimal timing of oocyte recovery for in vitro maturation and fertilization is still critical. Therefore the aim of the present study was to use high-resolution transcutaneous ultrasonography to monitor follicular development within xenografted ovarian tissue. Ovarian cortex fragments (n=44) from domestic cats were transplanted into athymic nude rats (n=12). Graft development in the animals was assessed weekly by high frequency ultrasound (10-22 MHz) under two different FSH regimes. Blood collection for serum estradiol determination and vaginal smears were performed simultaneously. The xenografts were removed at different time points according to the ultrasound findings. The survival rate of the transplants 4 weeks after surgery was 54.5% and antral follicular growth was observed within 10 grafts from 5 different hosts (8.6 +/- 6.43 follicles per graft). Early follicle antrums could be detected from 0.4 mm onwards. The growth rate of the antral cavity was calculated from weekly measurements (0.56 +/- 0.44 mm per week). Although vaginal cells and estradiol levels followed a cyclic pattern, no correlation was found between follicular diameter, estradiol and keratinized vaginal cells. We recovered 5, 1 and 4 cumulus oocyte complexes from three different individuals during weeks 19, 21, and 23 respectively. Extrusion of a polar body (1 oocyte) and germinal vesicle break down (7 oocytes) indicated progression of maturation after in vitro culture. We conclude that ultrasonography und provided a reliable method to examine xenograft survival and follicular development within the grafts. Furthermore, this technique is suitable for assessment of the efficiency of hormonal treatment and narrowing of the optimal time frame for oocyte retrieval. To our knowledge, this is the first report of the in vivo development of early antral follicles in mammalian species.

  17. STUDY OF POSTERIOR FOSSA TUMORS BY HIGH RESOLUTION MRI

    Directory of Open Access Journals (Sweden)

    Sree Hari

    2016-01-01

    Full Text Available INTRODUCTION Magnetic Resonance Imaging (MRI is the imaging modality used for the assessment of infratentorial neoplasms. Although Computed Tomography (CT provides better demonstration of small or subtle calcifications within tumors. OBJECTIVES Study is done to assess the potential of MRI in characterisation of different tumors in posterior fossa by evaluating various unenhanced and gadolinium enhanced sequences and to compare high resolution FSE MRI sequences with routine FSE MRI sequences in diagnosing posterior fossa brain tumors. Also correlate findings on Magnetic Resonance Imaging with Pathological diagnosis. MATERIALS AND METHODS A total of 52 patients were diagnosed by CT brain as having posterior fossa brain for a year of 2 years were included in the study. In all studies MR imaging was performed with a clinical 1.5 T system (General electrical medical systems. A dedicated phased-array coil was used. RESULTS The age group ranged from 1 year to 60 years, majority were between 1 to 20 years (39%. Slight male preponderance was seen (males 29, females 23. Commonest tumor encountered in our study was vestibular schwannoma. DWI alone can differentiate different pediatric posterior fossa brain tumors. One case of pilocytic astrocytoma showed solid lesion instead of typical cystic lesion with mural nodule. One case AT-RT showed 2 lesions one in cerebrum, one in CP angle. Common feature being intra-axial lesion involving cerebellum. MRI was able to predict diagnosis in 50 of the 52 tumors. CONCLUSION Magnetic Resonance Imaging was found to be a highly sensitive imaging procedure and method of choice for posterior fossa brain tumors.

  18. High resolution helium ion scanning microscopy of the rat kidney.

    Science.gov (United States)

    Rice, William L; Van Hoek, Alfred N; Păunescu, Teodor G; Huynh, Chuong; Goetze, Bernhard; Singh, Bipin; Scipioni, Larry; Stern, Lewis A; Brown, Dennis

    2013-01-01

    Helium ion scanning microscopy is a novel imaging technology with the potential to provide sub-nanometer resolution images of uncoated biological tissues. So far, however, it has been used mainly in materials science applications. Here, we took advantage of helium ion microscopy to explore the epithelium of the rat kidney with unsurpassed image quality and detail. In addition, we evaluated different tissue preparation methods for their ability to preserve tissue architecture. We found that high contrast, high resolution imaging of the renal tubule surface is possible with a relatively simple processing procedure that consists of transcardial perfusion with aldehyde fixatives, vibratome tissue sectioning, tissue dehydration with graded methanol solutions and careful critical point drying. Coupled with the helium ion system, fine details such as membrane texture and membranous nanoprojections on the glomerular podocytes were visualized, and pores within the filtration slit diaphragm could be seen in much greater detail than in previous scanning EM studies. In the collecting duct, the extensive and striking apical microplicae of the intercalated cells were imaged without the shrunken or distorted appearance that is typical with conventional sample processing and scanning electron microscopy. Membrane depressions visible on principal cells suggest possible endo- or exocytotic events, and central cilia on these cells were imaged with remarkable preservation and clarity. We also demonstrate the use of colloidal gold probes for highlighting specific cell-surface proteins and find that 15 nm gold labels are practical and easily distinguishable, indicating that external labels of various sizes can be used to detect multiple targets in the same tissue. We conclude that this technology represents a technical breakthrough in imaging the topographical ultrastructure of animal tissues. Its use in future studies should allow the study of fine cellular details and provide

  19. High resolution helium ion scanning microscopy of the rat kidney.

    Directory of Open Access Journals (Sweden)

    William L Rice

    Full Text Available Helium ion scanning microscopy is a novel imaging technology with the potential to provide sub-nanometer resolution images of uncoated biological tissues. So far, however, it has been used mainly in materials science applications. Here, we took advantage of helium ion microscopy to explore the epithelium of the rat kidney with unsurpassed image quality and detail. In addition, we evaluated different tissue preparation methods for their ability to preserve tissue architecture. We found that high contrast, high resolution imaging of the renal tubule surface is possible with a relatively simple processing procedure that consists of transcardial perfusion with aldehyde fixatives, vibratome tissue sectioning, tissue dehydration with graded methanol solutions and careful critical point drying. Coupled with the helium ion system, fine details such as membrane texture and membranous nanoprojections on the glomerular podocytes were visualized, and pores within the filtration slit diaphragm could be seen in much greater detail than in previous scanning EM studies. In the collecting duct, the extensive and striking apical microplicae of the intercalated cells were imaged without the shrunken or distorted appearance that is typical with conventional sample processing and scanning electron microscopy. Membrane depressions visible on principal cells suggest possible endo- or exocytotic events, and central cilia on these cells were imaged with remarkable preservation and clarity. We also demonstrate the use of colloidal gold probes for highlighting specific cell-surface proteins and find that 15 nm gold labels are practical and easily distinguishable, indicating that external labels of various sizes can be used to detect multiple targets in the same tissue. We conclude that this technology represents a technical breakthrough in imaging the topographical ultrastructure of animal tissues. Its use in future studies should allow the study of fine cellular details

  20. Johann Spectrometer for High Resolution X-ray Spectroscopy

    Science.gov (United States)

    Machek, Pavel; Welter, Edmund; Caliebe, Wolfgang; Brüggmann, Ulf; Dräger, Günter; Fröba, Michael

    2007-01-01

    A newly designed vacuum Johann spectrometer with a large focusing analyzer crystal for inelastic x-ray scattering and high resolution fluorescence spectroscopy has been installed at the DORIS III storage ring. Spherically bent crystals with a maximum diameter of 125 mm, and cylindrically bent crystals are employed as dispersive optical elements. Standard radius of curvature of the crystals is 1000 mm, however, the design of the mechanical components also facilitates measurements with smaller and larger bending radii. Up to four crystals are mounted on a revolving crystal changer which enables crystal changes without breaking the vacuum. The spectrometer works at fixed Bragg angle. It is preferably designed for the measurements in non-scanning mode with a broad beam spot, and offers a large flexibility to set the sample to the optimum position inside the Rowland circle. A deep depletion CCD camera is employed as a position sensitive detector to collect the energy-analyzed photons on the circumference of the Rowland circle. The vacuum in the spectrometer tank is typically 10-6 mbar. The sample chamber is separated from the tank either by 25 μm thick Kapton windows, which allows samples to be measured under ambient conditions, or by two gate valves. The spectrometer is currently installed at wiggler beamline W1 whose working range is 4-10.5 keV with typical flux at the sample of 5×1010photons/s/mm2. The capabilities of the spectrometer are illustrated by resonant inelastic experiments on 3d transition metals and rare earth compounds, and by chemical shift measurements on chromium compounds.

  1. High-resolution urban flood modelling - a joint probability approach

    Science.gov (United States)

    Hartnett, Michael; Olbert, Agnieszka; Nash, Stephen

    2017-04-01

    The hydrodynamic modelling of rapid flood events due to extreme climatic events in urban environment is both a complex and challenging task. The horizontal resolution necessary to resolve complexity of urban flood dynamics is a critical issue; the presence of obstacles of varying shapes and length scales, gaps between buildings and the complex geometry of the city such as slopes affect flow paths and flood levels magnitudes. These small scale processes require a high resolution grid to be modelled accurately (2m or less, Olbert et al., 2015; Hunter et al., 2008; Brown et al., 2007) and, therefore, altimetry data of at least the same resolution. Along with availability of high-resolution LiDAR data and computational capabilities, as well as state of the art nested modelling approaches, these problems can now be overcome. Flooding and drying, domain definition, frictional resistance and boundary descriptions are all important issues to be addressed when modelling urban flooding. In recent years, the number of urban flood models dramatically increased giving a good insight into various modelling problems and solutions (Mark et al., 2004; Mason et al., 2007; Fewtrell et al., 2008; Shubert et al., 2008). Despite extensive modelling work conducted for fluvial (e.g. Mignot et al., 2006; Hunter et al., 2008; Yu and Lane, 2006) and coastal mechanisms of flooding (e.g. Gallien et al., 2011; Yang et al., 2012), the amount of investigations into combined coastal-fluvial flooding is still very limited (e.g. Orton et al., 2012; Lian et al., 2013). This is surprising giving the extent of flood consequences when both mechanisms occur simultaneously, which usually happens when they are driven by one process such as a storm. The reason for that could be the fact that the likelihood of joint event is much smaller than those of any of the two contributors occurring individually, because for fast moving storms the rainfall-driven fluvial flood arrives usually later than the storm surge

  2. Convertible Stadium

    Science.gov (United States)

    1978-01-01

    Air flotation technology used in NASA's Apollo program has found an interesting application in Hawaii's Aloha Stadium near Honolulu. The stadium's configuration can be changed, by moving entire 7,000-seat sections on a cushion of air, for best accommodation of spectators and participants at different types of events. In most stadiums, only a few hundred seats can be moved, by rolling sections on wheels or rails. At Aloha Stadium, 28,000 of the 50,000 seats can be repositioned for better spectator viewing and, additionally, for improved playing conditions. For example, a stadium designed primarily for football may compromise the baseball diamond by providing only a shallow outfield. Aloha's convertibility allows a full-size baseball field as well as optimum configurations for many other types of sports and special events. The photos show examples. The stadium owes its versatility to air flotation technology developed by General Motors. Its first large-scale application was movement of huge segments of the mammoth Saturn V moonbooster during assembly operations at Marshall Space Flight Center.

  3. Preparation and characterization of pixelated phosphor screens for high-resolution linear imaging in the vacuum ultraviolet and x-ray ranges

    Science.gov (United States)

    Rodríguez-Barquero, L.; Zurro, B.; Martin, P.; McCarthy, K. J.; Baciero, A.

    2004-10-01

    Indirect digital imaging sensors employ tailored phosphors screens to convert incident x-ray or vacuum-ultraviolet (VUV) photons to visible light quanta A convenient method to prepare pixelated phosphor screens that can be easily tailored in thickness, type, and spatial resolution is presented. The characterization and evaluation of these screens in the laboratory is addressed and their application to high-resolution VUV and x-ray cameras is discussed.

  4. A high-resolution assessment of wind and wave energy potentials in the Red Sea

    KAUST Repository

    Langodan, Sabique

    2016-08-24

    This study presents an assessment of the potential for harvesting wind and wave energy from the Red Sea based on an 18-year high-resolution regional atmospheric reanalysis recently generated using the Advanced Weather Research Forecasting model. This model was initialized with ERA-Interim global data and the Red Sea reanalysis was generated using a cyclic three-dimensional variational approach assimilating available data in the region. The wave hindcast was generated using WAVEWATCH III on a 5 km resolution grid, forced by the Red Sea reanalysis surface winds. The wind and wave products were validated against data from buoys, scatterometers and altimeters. Our analysis suggests that the distribution of wind and wave energy in the Red Sea is inhomogeneous and is concentrated in specific areas, characterized by various meteorological conditions including weather fronts, mesoscale vortices, land and sea breezes and mountain jets. A detailed analysis of wind and wave energy variation was performed at three hotspots representing the northern, central and southern parts of the Red Sea. Although there are potential sites for harvesting wind energy from the Red Sea, there are no potential sites for harvesting wave energy because wave energy in the Red Sea is not strong enough for currently available wave energy converters. Wave energy should not be completely ignored, however, at least from the perspective of hybrid wind-wave projects. (C) 2016 Elsevier Ltd. All rights reserved.

  5. High resolution space quartz-flexure accelerometer based on capacitive sensing and electrostatic control technology

    Science.gov (United States)

    Tian, W.; Wu, S. C.; Zhou, Z. B.; Qu, S. B.; Bai, Y. Z.; Luo, J.

    2012-09-01

    High precision accelerometer plays an important role in space scientific and technical applications. A quartz-flexure accelerometer operating in low frequency range, having a resolution of better than 1 ng/Hz1/2, has been designed based on advanced capacitive sensing and electrostatic control technologies. A high precision capacitance displacement transducer with a resolution of better than 2 × 10-6 pF/Hz1/2 above 0.1 Hz, is used to measure the motion of the proof mass, and the mechanical stiffness of the spring oscillator is compensated by adjusting the voltage between the proof mass and the electrodes to induce a proper negative electrostatic stiffness, which increases the mechanical sensitivity and also suppresses the position measurement noise down to 3 × 10-10 g/Hz1/2 at 0.1 Hz. A high resolution analog-to-digital converter is used to directly readout the feedback voltage applied on the electrodes in order to suppress the action noise to 4 × 10-10 g/Hz1/2 at 0.1 Hz. A prototype of the quartz-flexure accelerometer has been developed and tested, and the preliminary experimental result shows that its resolution comes to about 8 ng/Hz1/2 at 0.1 Hz, which is mainly limited by its mechanical thermal noise due to low quality factor.

  6. A high-resolution map of synteny disruptions in gibbon and human genomes.

    Directory of Open Access Journals (Sweden)

    Lucia Carbone

    2006-12-01

    Full Text Available Gibbons are part of the same superfamily (Hominoidea as humans and great apes, but their karyotype has diverged faster from the common hominoid ancestor. At least 24 major chromosome rearrangements are required to convert the presumed ancestral karyotype of gibbons into that of the hominoid ancestor. Up to 28 additional rearrangements distinguish the various living species from the common gibbon ancestor. Using the northern white-cheeked gibbon (2n = 52 (Nomascus leucogenys leucogenys as a model, we created a high-resolution map of the homologous regions between the gibbon and human. The positions of 100 synteny breakpoints relative to the assembled human genome were determined at a resolution of about 200 kb. Interestingly, 46% of the gibbon-human synteny breakpoints occur in regions that correspond to segmental duplications in the human lineage, indicating a common source of plasticity leading to a different outcome in the two species. Additionally, the full sequences of 11 gibbon BACs spanning evolutionary breakpoints reveal either segmental duplications or interspersed repeats at the exact breakpoint locations. No specific sequence element appears to be common among independent rearrangements. We speculate that the extraordinarily high level of rearrangements seen in gibbons may be due to factors that increase the incidence of chromosome breakage or fixation of the derivative chromosomes in a homozygous state.

  7. High-resolution photoelectron spectroscopy analysis of sulfidation of brass at the rubber/brass interface

    Energy Technology Data Exchange (ETDEWEB)

    Ozawa, Kenichi, E-mail: ozawa.k.ab@m.titech.ac.jp [Department of Chemistry and Materials Science, Tokyo Institute of Technology, Ookayama, Meguro-ku, Tokyo 152-8551 (Japan); Kakubo, Takashi; Shimizu, Katsunori; Amino, Naoya [Yokohama Rubber Co., Ltd., Oiwake, Hiratsuka 254-8601 (Japan); Mase, Kazuhiko [Institute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), Tsukuba 305-0801 (Japan); Komatsu, Takayuki [Department of Chemistry and Materials Science, Tokyo Institute of Technology, Ookayama, Meguro-ku, Tokyo 152-8551 (Japan)

    2013-01-01

    Highlights: Black-Right-Pointing-Pointer Chemical composition at the rubber/brass interface is investigated. Black-Right-Pointing-Pointer The 2-min vulcanization reaction is enough to convert the interface composition. Black-Right-Pointing-Pointer Five S-containing species are identified at the interface. Black-Right-Pointing-Pointer Strong rubber-brass adhesion is related to the Cu{sub 2}S/CuS ratio. Black-Right-Pointing-Pointer Degradation of adhesion proceeds along with desulfidation of the interface. - Abstract: High resolution photoelectron spectroscopy is utilized to investigate the chemical composition at the rubber/brass interface to elucidate the origin of strong adhesion as well as the degradation between rubber and brass. Special attention has been given to copper sulfides formed at the interface during the vulcanization reaction at 170 Degree-Sign C. At least five sulfur-containing species are identified in the adhesive interlayer including crystalline CuS and amorphous Cu{sub x}S (x Asymptotically-Equal-To 2). These copper sulfide species are not uniformly distributed within the layer, but there exits the concentration gradation; the concentration of Cu{sub x}S is high in the region on the rubber side and is diminished in the deeper region, while vice versa for that of CuS. Degradation of the interface adhesive strength by prolonged vulcanization arises from the decrease in the Cu{sub x}S/CuS ratio accompanying desulfurization of the adhesive layer.

  8. Low-cost and high-resolution interrogation scheme for LPG-based temperature sensor

    Science.gov (United States)

    Venkata Reddy, M.; Srimannarayana, K.; Venkatappa Rao, T.; Vengal Rao, P.

    2015-09-01

    A low-cost and high-resolution interrogation scheme for a long-period fiber grating (LPG) temperature sensor with adjustable temperature range has been designed, developed and tested. In general LPGs are widely used as optical sensors and can be used as optical edge filters to interrogate the wavelength encoded signal from sensors such as fiber Bragg grating (FBG) by converting it into intensity modulated signal. But the interrogation of LPG sensors using FBG is a bit novel and it is to be studied experimentally. The sensor works based on measurement of shift in attenuation band of LPG corresponding to the applied temperature. The wavelength shift of LPG attenuation band is monitored using an optical spectrum analyser (OSA). Further the bulk and expensive OSA is replaced with a low-cost interrogation system that employ an FBG, photodiode and a transimpedance amplifier (TIA). The designed interrogation scheme makes the system low-cost, fast in response, and also enhances its resolution up to 0.1°C. The measurable temperature range using the proposed scheme is limited to 120 °C. However this range can be shifted within 15-450 °C by means of adjusting the Bragg wavelength of FBG.

  9. High-resolution US findings of carpal tunnel syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Hyuk Won; Lee, Jin Hee; Rhee, Chang Soo; Lee, Sung Moon; Woo, Seong Ku [Keimyung University School of Medicine, Taegu (Korea, Republic of)

    2002-06-15

    To describe US findings of carpal tunnel syndrome (CTS) and to evaluate the diagnostic value of US in CTS by measuring the cross-sectional area of the median nerve. Thirty one wrists from 21 patients with CTS diagnosed clinically and by electromyography and thirty two wrists from 16 normal control patients were included. The age of the patients with CTS ranged 36 to 65 years (mean=51 years); the age of the normal control group, 31 to 62 years (mean=43 years). Axial images of the wrists at the levels of the radiocarpal joint (RCJ), mid-level of the lunate and the capitate in the neutral position were obtained. The cross sectional area (CSA) of the median nerve was calculated at three levels using a indirect method by employing a ellipse tool programmed built in sonographic machine. In patients with CTS, CSA measured at the radiocarpal joint, mid-level of the lunate and capitate were 12.35 {+-} 3.90 mm{sup 2}, 14.68 {+-} 3.83 mm{sup 2} and 8.48 {+-} 1.88 mm'2, respectively. On the other hand, CSA of the control group, 8.44 {+-} 1.41 mm{sup 2}, 8.75 {+-} 1.46 mm{sup 2}, and 8.19 {+-} 1.47 mm{sup 2}, respectively. CSA at the radiocarpal joint and the mid lunate was bigger (or larger) in patients with CTS than in that of the controls with a statistical significance (P<0.05) while CSA at the mid capitate was slightly bigger in patients with CTS than that of the controls but without a statistical significance. CSA of the median nerve over 12 mm{sup 2} at the mid lunate level was highly predictive of carpal tunnel syndrome (sensitivity=80.6%, specificity=93.8%, positive predictive value=92.6%, negative predictive value=83.3%, and likelihood ratio=13). High resolution US can be useful in diagnosis of CTS, and CSA of the median nerve over 12 mm{sup 2} at the mid lunate level is highly predictive of carpal tunnel syndrome.

  10. Attracting retinal cells to electrodes for high-resolution stimulation

    Science.gov (United States)

    Palanker, Daniel V.; Huie, Philip; Vankov, Alexander B.; Freyvert, Yev; Fishman, Harvey; Marmor, Michael F.; Blumenkranz, Mark S.

    2004-07-01

    Development of the electronic retinal prosthesis for restoration of sight in patients suffering from the degenerative retinal diseases faces many technological challenges. To achieve significant improvement in the low vision patients the visual acuity of 20/80 would be desirable, which corresponds to the pixel size of 20μm in the retinal implant. Stimulating current strongly (quadratically) depends on distance between electrode and cell. To achieve uniformity in stimulation thresholds, to avoid erosion of the electrodes and overheating of tissue, and to reduce the cross-talk between the neighboring pixels the neural cells should not be separated from electrodes by more than a few micrometers. Achieving such a close proximity along the whole surface of an implant is one of the major obstacles for the high resolution retinal implant. To ensure proximity of cells and electrodes we have developed a technique that prompts migration of retinal cells towards stimulating sites. The device consists of a multilayered membrane with an array of perforations of several (5-15) micrometers in diameter in which addressable electrodes can be embedded. In experiments in-vitro using explants of the whole retina of P7 rats, and in-vivo using adult rabbits and RCS rats the retinal tissue grew into the pores when membranes were positioned on the sub-retinal side. Histology has demonstrated that migrating cells preserve synaptic connections with cells outside the pores, thus allowing for signal transduction into the retina above the implant. Intimate proximity of cells to electrodes achieved with this technique allows for reduction of the stimulation current to 2μA at the 10μm electrode. A 3mm disk array with 18,000 pixels can stimulate cells with 0.5 ms pulses at 50Hz while maintaining temperature rise at the implant surface below 0.3°C. Such an implant can, in principle, provide spatial resolution geometrically corresponding to the visual acuity of 20/80 in a visual field of 10°.

  11. High resolution gas chromatography analysis of rice bran oil

    Science.gov (United States)

    Yu, Fengxiang; Lin, Qinlu; Chen, Xu; Wei, Xiaojun

    To assess the nutritional value and safety quality of rice bran oil (RBO) ,fatty acids of RBO from 15 species rice come from Hunan Province were analyzed by high resolution gas chromatography (HRGC). Crude RBOs were extracted by hexane 3-times using a solvent-to-rice bran ratio of 3:1 (w/w) at 40°C and composition of RBOs was analyzed by HRGC. The result showed that main fatty acids of 15 kinds of RBO include myristic acid (C14:0), palmitic acid (C16:0), palmitoleic acid (C16:1), stearic acid (C18:0), oleic acid (C18:1), linoleic acid (C18:2), linolenic acid (C18:3), arachidic acid (C20:0), arachidonic acid (C20:1). It is strange that arachidonic acid (C20:1) is not listed in Chinese standard of RBO (GB11192-2003), and it exists in our samples of RBO. The average value of linolenic acid in RBOs is 1.6304% (range from 1.2425% to 2.131%), and it showed higher level comparing with Chinese standard that linolenic acid is less than 1.0%. The average value of USFA and SFA are 76.81% (range 75.96% to 82.06% ) and 20.15% (range 13.72% to 23.06%) respectively, and USFA content is close to olive oil (83.75%), peanut oil (81.75%) and soybean oil (85.86%). USFA in Jingyou 13 RBO is the highest content. The ratio of USFA to SFA content is 4:1 (range from 3.32 to 5.98:1). The ratio of SFA: MUFA: PUFA of 15 RBOs is 1: 2.2: 1.8, and ω6/ω3 ratio is 21.69 (range from16.54 to 27.28) and it is close to the 26:1 which is reported to be helpful to increase SOD activity. The oleic acid /linoleic acid ratio of 15 RBOs is 1.23:1 (rang from 1.04:1 to 1.42:1). Our data analyzed composition of RBOs from 15 species rice of China and will provide new evidence to revise RBO standard. It also helps us to assess nutritional value of RBOs and identify different RBOs from various species rice and places of origin.

  12. High resolution modeling of a small urban catchment

    Science.gov (United States)

    Skouri-Plakali, Ilektra; Ichiba, Abdellah; Gires, Auguste; Tchiguirinskaia, Ioulia; Schertzer, Daniel

    2016-04-01

    Flooding is one of the most complex issues that urban environments have to deal with. In France, flooding remains the first natural risk with 72% of decrees state of natural disaster issued between October 1982 and mid-November 2014. Flooding is a result of meteorological extremes that are usually aggravated by the hydrological behavior of urban catchments and human factors. The continuing urbanization process is indeed changing the whole urban water cycle by limiting the infiltration and promoting runoff. Urban environments are very complex systems due to their extreme variability, the interference between human activities and natural processes but also the effect of the ongoing urbanization process that changes the landscape and hardly influences their hydrologic behavior. Moreover, many recent works highlight the need to simulate all urban water processes at their specific temporal and spatial scales. However, considering urban catchments heterogeneity still challenging for urban hydrology, even after advances noticed in term of high-resolution data collection and computational resources. This issue is more to be related to the architecture of urban models being used and how far these models are ready to take into account the extreme variability of urban catchments. In this work, high spatio-temporal resolution modeling is performed for a small and well-equipped urban catchment. The aim of this work is to identify urban modeling needs in terms of spatial and temporal resolution especially for a very small urban area (3.7 ha urban catchment located in the Perreux-sur-Marne city at the southeast of Paris) MultiHydro model was selected to carry out this work, it is a physical based and fully distributed model that interacts four existing modules each of them representing a portion of the water cycle in urban environments. MultiHydro was implemented at 10m, 5m and 2m resolution. Simulations were performed at different spatio-temporal resolutions and analyzed with

  13. Visualization of small scale structures on high resolution DEMs

    Science.gov (United States)

    Kokalj, Žiga; Zakšek, Klemen; Pehani, Peter; Čotar, Klemen; Oštir, Krištof

    2015-04-01

    Knowledge on the terrain morphology is very important for observation of numerous processes and events and digital elevation models are therefore one of the most important datasets in geographic analyses. Furthermore, recognition of natural and anthropogenic microrelief structures, which can be observed on detailed terrain models derived from aerial laser scanning (lidar) or structure-from-motion photogrammetry, is of paramount importance in many applications. In this paper we thus examine and evaluate methods of raster lidar data visualization for the determination (recognition) of microrelief features and present a series of strategies to assist selecting the preferred visualization of choice for structures of various shapes and sizes, set in varied landscapes. Often the answer is not definite and more frequently a combination of techniques has to be used to map a very diverse landscape. Researchers can only very recently benefit from free software for calculation of advanced visualization techniques. These tools are often difficult to understand, have numerous options that confuse the user, or require and produce non-standard data formats, because they were written for specific purposes. We therefore designed the Relief Visualization Toolbox (RVT) as a free, easy-to-use, standalone application to create visualisations from high-resolution digital elevation data. It is tailored for the very beginners in relief interpretation, but it can also be used by more advanced users in data processing and geographic information systems. It offers a range of techniques, such as simple hillshading and its derivatives, slope gradient, trend removal, positive and negative openness, sky-view factor, and anisotropic sky-view factor. All included methods have been proven to be effective for detection of small scale features and the default settings are optimised to accomplish this task. However, the usability of the tool goes beyond computation for visualization purposes, as sky

  14. POLLUX: A UV High-Resolution Spectropolatimeter for LUVOIR

    Science.gov (United States)

    Bouret, Jean-Claude; Neiner, Coralie; Lopez Ariste, Arturo; Vivès, Sébastien; Muslimov, Eduard; Lopes, Louise; Costeraste, Josiane; Brachet, Frank; POLLUX Consortium

    2018-01-01

    The Large Ultraviolet/Optical/Infrared Surveyor (LUVOIR) is one of four large mission concept studies led by NASA for the 2020 Decadal Survey. A versatile suite of instruments is envisioned for LUVOIR, to advance our understanding of the origin and evolution of galaxies, stars and planets that make up our Universe, and the life within it. We present POLLUX, a high-resolution spectropolarimeter, operating at UV wavelengths, designed for the 15-meter primary mirror option of LUVOIR. POLLUX study is supported by the French Space Agency (CNES) and developed by a European consortium of scientists.POLLUX will operate over a broad spectral range (98 to 390 nm), at high spectral resolution (R = 120,000). This will permit to resolve narrow UV emission and absorption lines, thus to follow the baryon cycle over cosmic time, from galaxies forming stars out of interstellar gas and grains, and stars forming planets, to the various forms of feedback into the interstellar and intergalactic medium (ISM and IGM), and active galactic nuclei (AGN).The most innovative characteristic of POLLUX is its unique spectropolarimetric capability, that will enable detection of the polarized light reflected from Earth-like exoplanets or from their circumplanetary material, and moons, and characterization of the magnetospheres of stars and planets, and their interactions. The magnetospheric properties of planets in the solar system will be accessible to exquisite level of details, while the influence of magnetic fields at the galactic scale and in the IGM will be measured. UV circular and linear polarisation will provide a full picture of magnetic field properties and impact for a variety of media and objects, from AGN outflows to all types of stars. It will probe the physics of accretion disks around young stars and white dwarfs, or supermassive black holes in AGNs, and constrain the properties, especially sphericity, of stellar ejecta and explosions. Since the parameter space opened by POLLUX is

  15. Visualizing sediment dynamics through repeated high-resolution multibeam mapping

    Science.gov (United States)

    de Vries, J. J.; Greinert, J.; Maierhofer, T.

    2013-12-01

    abundance of smaller ripples and different net-transport rates of sediment into the Wadden Sea. Vertical stratification in the Marsdiep is determined by salinity with stronger vertical stratification in winter time. The Texelstroom channel is ebb-dominant with an outflow over the entire water column. However, during more vertically stratified conditions, the residual circulation is smaller at the bottom because the outflow at the surface is balanced at the bottom resulting in more symmetrical sand waves in summer. The repeated high-resolution multibeam surveys shed light on the highly dynamic seasonal behavior of sand waves in the Texelstroom channel and corroborates the high value of repeated multibeam surveys to visualize these dynamics.

  16. Impacts of high resolution model downscaling in coastal regions

    Science.gov (United States)

    Bricheno, Lucy; Wolf, Judith

    2013-04-01

    With model development and cheaper computational resources ocean forecasts are becoming readily available, high resolution coastal forecasting is now a reality. This can only be achieved, however, by downscaling global or basin-scale products such as the MyOcean reanalyses and forecasts. These model products have resolution ranging from 1/16th - 1/4 degree, which are often insufficient for coastal scales, but can provide initialisation and boundary data. We present applications of downscaling the MyOcean products for use in shelf-seas and the nearshore. We will address the question 'Do coastal predictions improve with higher resolution modelling?' with a few focused examples, while also discussing what is meant by an improved result. Increasing resolution appears to be an obvious route for getting more accurate forecasts in operational coastal models. However, when models resolve finer scales, this may lead to the introduction of high-frequency variability which is not necessarily deterministic. Thus a flow may appear more realistic by generating eddies but the simple statistics like rms error and correlation may become less good because the model variability is not exactly in phase with the observations (Hoffman et al., 1995). By deciding on a specific process to simulate (rather than concentrating on reducing rms error) we can better assess the improvements gained by downscaling. In this work we will select two processes which are dominant in our case-study site: Liverpool Bay. Firstly we consider the magnitude and timing of a peak in tide-surge elevations, by separating out the event into timing (or displacement) and intensity (or amplitude) errors. The model can thus be evaluated on how well it predicts the timing and magnitude of the surge. The second important characteristic of Liverpool Bay is the position of the freshwater front. To evaluate model performance in this case, the location, sharpness, and temperature difference across the front will be

  17. High-resolution field shaping utilizing a masked multileaf collimator.

    Science.gov (United States)

    Williams, P C; Cooper, P

    2000-08-01

    Multileaf collimators (MLCs) have become an important tool in the modern radiotherapy department. However, the current limit of resolution (1 cm at isocentre) can be too coarse for acceptable shielding of all fields. A number of mini- and micro-MLCs have been developed, with thinner leaves to achieve approved resolution. Currently however, such devices are limited to modest field sizes and stereotactic applications. This paper proposes a new method of high-resolution beam collimation by use of a tertiary grid collimator situated below the conventional MLC. The width of each slit in the grid is a submultiple of the MLC width. A composite shaped field is thus built up from a series of subfields, with the main MLC defining the length of each strip within each subfield. Presented here are initial findings using a prototype device. The beam uniformity achievable with such a device was examined by measuring transmission profiles through the grid using a diode. Profiles thus measured were then copied and superposed to generate composite beams, from which the uniformity achievable could be assessed. With the average dose across the profile normalized to 100%, hot spots up to 5.0% and troughs of 3% were identified for a composite beam of 2 x 5.0 mm grids, as measured at Dmax for a 6 MV beam. For a beam composed from 4 x 2.5 mm grids, the maximum across the profile was 3.0% above the average, and the minimum 2.5% below. Actual composite profiles were also formed using the integrating properties of film, with the subfield indexing performed using an engineering positioning stage. The beam uniformity for these fields compared well with that achieved in theory using the diode measurements. Finally sine wave patterns were generated to demonstrate the potential improvements in field shaping and conformity using this device as opposed to the conventional MLC alone. The scalloping effect on the field edge commonly seen on MLC fields was appreciably reduced by use of 2 x 5.0 mm

  18. A High-Resolution Sensor Network for Monitoring Glacier Dynamics

    Science.gov (United States)

    Edwards, S.; Murray, T.; O'Farrell, T.; Rutt, I. C.; Loskot, P.; Martin, I.; Selmes, N.; Aspey, R.; James, T.; Bevan, S. L.; Baugé, T.

    2013-12-01

    Changes in Greenland and Antarctic ice sheets due to ice flow/ice-berg calving are a major uncertainty affecting sea-level rise forecasts. Latterly GNSS (Global Navigation Satellite Systems) have been employed extensively to monitor such glacier dynamics. Until recently however, the favoured methodology has been to deploy sensors onto the glacier surface, collect data for a period of time, then retrieve and download the sensors. This approach works well in less dynamic environments where the risk of sensor loss is low. In more extreme environments e.g. approaching the glacial calving front, the risk of sensor loss and hence data loss increases dramatically. In order to provide glaciologists with new insights into flow dynamics and calving processes we have developed a novel sensor network to increase the robustness of data capture. We present details of the technological requirements for an in-situ Zigbee wireless streaming network infrastructure supporting instantaneous data acquisition from high resolution GNSS sensors thereby increasing data capture robustness. The data obtained offers new opportunities to investigate the interdependence of mass flow, uplift, velocity and geometry and the network architecture has been specifically designed for deployment by helicopter close to the calving front to yield unprecedented detailed information. Following successful field trials of a pilot three node network during 2012, a larger 20 node network was deployed on the fast-flowing Helheim glacier, south-east Greenland over the summer months of 2013. The utilisation of dual wireless transceivers in each glacier node, multiple frequencies and four ';collector' stations located on the valley sides creates overlapping networks providing enhanced capacity, diversity and redundancy of data 'back-haul', even close to ';floor' RSSI (Received Signal Strength Indication) levels around -100 dBm. Data loss through radio packet collisions within sub-networks are avoided through the

  19. eWaterCycle: A high resolution global hydrological model

    Science.gov (United States)

    van de Giesen, Nick; Bierkens, Marc; Drost, Niels; Hut, Rolf; Sutanudjaja, Edwin

    2014-05-01

    In 2013, the eWaterCycle project was started, which has the ambitious goal to run a high resolution global hydrological model. Starting point was the PCR-GLOBWB built by Utrecht University. The software behind this model will partially be re-engineered in order to enable to run it in a High Performance Computing (HPC) environment. The aim is to have a spatial resolution of 1km x 1km. The idea is also to run the model in real-time and forecasting mode, using data assimilation. An on-demand hydraulic model will be available for detailed flow and flood forecasting in support of navigation and disaster management. The project faces a set of scientific challenges. First, to enable the model to run in a HPC environment, model runs were analyzed to examine on which parts of the program most CPU time was spent. These parts were re-coded in Open MPI to allow for parallel processing. Different parallelization strategies are thinkable. In our case, it was decided to use watershed logic as a first step to distribute the analysis. There is rather limited recent experience with HPC in hydrology and there is much to be learned and adjusted, both on the hydrological modeling side and the computer science side. For example, an interesting early observation was that hydrological models are, due to their localized parameterization, much more memory intensive than models of sister-disciplines such as meteorology and oceanography. Because it would be deadly to have to swap information between CPU and hard drive, memory management becomes crucial. A standard Ensemble Kalman Filter (enKF) would, for example, have excessive memory demands. To circumvent these problems, an alternative to the enKF was developed that produces equivalent results. This presentation shows the most recent results from the model, including a 5km x 5km simulation and a proof of concept for the new data assimilation approach. Finally, some early ideas about financial sustainability of an operational global

  20. High-resolution measurements of humidity and temperature with lidar

    Science.gov (United States)

    Behrendt, Andreas; Wulfmeyer, Volker; Spaeth, Florian; Hammann, Eva; Muppa, Shravan Kumar; Metzendorf, Simon; Riede, Andrea

    2015-04-01

    3-dimensional thermodynamic fields of temperature and moisture including their turbulent fluctuations have been observed with the two scanning lidar systems of University of Hohenheim in three field campaigns in 2013 and 2014. In this contribution, we will introduce these two self-developed instruments and illustrate their performance with measurement examples. Finally, an outlook to envisioned future research activities with the new data sets of the instruments is given. Our temperature lidar is based on the rotational Raman technique. The scanning rotational Raman lidar (RRL) uses a seeded frequency-doubled Nd:YAG laser at a wavelength of 355 nm. A two-mirror scanner with a 40-cm telescope collects the atmospheric backscatter signals. Humidity measurements are made with a scanning water vapor differential absorption lidar (DIAL) which uses a titanium sapphire laser at 820 nm as transmitter. This laser is pumped with a frequency-doubled Nd:YAG laser and injection-seeded for switching between the online and offline wavelengths. The DIAL receiver consists of a scanning 80-cm telescope. The measured temperature and humidity profiles of both instruments have typical resolutions of only a few seconds and 100 m in the atmospheric boundary layer both in day- and night-time. Recent field experiments with the RRL and the DIAL of University of Hohenheim were (1) the HD(CP)2 Prototype Experiment (HOPE) in spring 2013 in western Germany - this activity is embedded in the project HD(CP)2 (High-definition clouds and precipitation for advancing climate prediction); (2) a measurement campaign in Hohenheim in autumn 2013; (3) the campaign SABLE (Surface Atmospheric Boundary Layer Exchange) in south-western Germany in summer 2014. The collected moisture and temperature data will serve as initial thermodynamic fields for forecast experiments related to the formation of clouds and precipitation. Due to their high resolution and high precision, the systems are capable of resolving

  1. Performance evaluation of a high resolution dedicated breast PET scanner

    Energy Technology Data Exchange (ETDEWEB)

    García Hernández, Trinitat, E-mail: mtrinitat@eresa.com; Vicedo González, Aurora; Brualla González, Luis; Granero Cabañero, Domingo [Department of Medical Physics, ERESA, Hospital General Universitario, Valencia 46014 (Spain); Ferrer Rebolleda, Jose; Sánchez Jurado, Raúl; Puig Cozar Santiago, Maria del [Department of Nuclear Medicine, ERESA, Hospital General Universitario, Valencia 46014 (Spain); Roselló Ferrando, Joan [Department of Medical Physics, ERESA, Hospital General Universitario, Valencia 46014 (Spain); Department of Physiology, University of Valencia, Valencia 46010 (Spain)

    2016-05-15

    Purpose: Early stage breast cancers may not be visible on a whole-body PET scan. To overcome whole-body PET limitations, several dedicated breast positron emission tomography (DbPET) systems have emerged nowadays aiming to improve spatial resolution. In this work the authors evaluate the performance of a high resolution dedicated breast PET scanner (Mammi-PET, Oncovision). Methods: Global status, uniformity, sensitivity, energy, and spatial resolution were measured. Spheres of different sizes (2.5, 4, 5, and 6 mm diameter) and various 18 fluorodeoxyglucose ({sup 18}F-FDG) activity concentrations were randomly inserted in a gelatine breast phantom developed at our institution. Several lesion-to-background ratios (LBR) were simulated, 5:1, 10:1, 20:1, 30:1, and 50:1. Images were reconstructed using different voxel sizes. The ability of experienced reporters to detect spheres was tested as a function of acquisition time, LBR, sphere size, and matrix reconstruction voxel size. For comparison, phantoms were scanned in the DbPET camera and in a whole body PET (WB-PET). Two patients who just underwent WB-PET/CT exams were imaged with the DbPET system and the images were compared. Results: The measured absolute peak sensitivity was 2.0%. The energy resolution was 24.0% ± 1%. The integral and differential uniformity were 10% and 6% in the total field of view (FOV) and 9% and 5% in the central FOV, respectively. The measured spatial resolution was 2.0, 1.9, and 1.7 mm in the radial, tangential, and axial directions. The system exhibited very good detectability for spheres ≥4 mm and LBR ≥10 with a sphere detection of 100% when acquisition time was set >3 min/bed. For LBR = 5 and acquisition time of 7 min the detectability was 100% for spheres of 6 mm and 75% for spheres of 5, 4, and 2.5 mm. Lesion WB-PET detectability was only comparable to the DbPET camera for lesion sizes ≥5 mm when acquisition time was >3 min and LBR > 10. Conclusions: The DbPET has a good

  2. Object oriented classification of high resolution data for inventory of horticultural crops

    Science.gov (United States)

    Hebbar, R.; Ravishankar, H. M.; Trivedi, S.; Subramoniam, S. R.; Uday, R.; Dadhwal, V. K.

    2014-11-01

    High resolution satellite images are associated with large variance and thus, per pixel classifiers often result in poor accuracy especially in delineation of horticultural crops. In this context, object oriented techniques are powerful and promising methods for classification. In the present study, a semi-automatic object oriented feature extraction model has been used for delineation of horticultural fruit and plantation crops using Erdas Objective Imagine. Multi-resolution data from Resourcesat LISS-IV and Cartosat-1 have been used as source data in the feature extraction model. Spectral and textural information along with NDVI were used as inputs for generation of Spectral Feature Probability (SFP) layers using sample training pixels. The SFP layers were then converted into raster objects using threshold and clump function resulting in pixel probability layer. A set of raster and vector operators was employed in the subsequent steps for generating thematic layer in the vector format. This semi-automatic feature extraction model was employed for classification of major fruit and plantations crops viz., mango, banana, citrus, coffee and coconut grown under different agro-climatic conditions. In general, the classification accuracy of about 75-80 per cent was achieved for these crops using object based classification alone and the same was further improved using minimal visual editing of misclassified areas. A comparison of on-screen visual interpretation with object oriented approach showed good agreement. It was observed that old and mature plantations were classified more accurately while young and recently planted ones (3 years or less) showed poor classification accuracy due to mixed spectral signature, wider spacing and poor stands of plantations. The results indicated the potential use of object oriented approach for classification of high resolution data for delineation of horticultural fruit and plantation crops. The present methodology is applicable at

  3. A high resolution (1 km) groundwater model for Indonesia

    Science.gov (United States)

    Sutanudjaja, Edwin; Verkaik, Jarno; de Graaf, Inge; van Beek, Rens; Erkens, Gilles; Bierkens, Marc

    2015-04-01

    results. Also we discuss fundamental challenges in high resolution groundwater modeling and address various issues that range from computational challenges - e.g. computational time, memory, and parallelization issues - to lack of sufficient detail/fine information for model validation and parameterization - including atmospheric forcing and emergent scaling problems. References: de Graaf et al., Hydrology & Earth System Sciences (2014), http://dx.doi.org/10.5194/hessd-11-5217-2014 Dürr et al., Global Biogeochemical Cycles (2005), http://dx.doi.org/10.1029/2005GB002515 Gleeson et al., Geophysical Research Letter (2011), http://dx.doi.org/10.1029/2010GL045565 Gleeson et al., Geophysical Research Letter (2014), http://dx.doi.org/10.1002/2014GL059856 Harbaugh et al., MODFLOW-2000 (2000), http://water.usgs.gov/nrp/gwsoftware/modflow2000/ofr00-92.pdf Hartmann & Moosdorf, Geochemistry Geophysics Geosystems (2012), http://dx.doi.org/10.1029/2012GC004370 Sutanudjaja et al., Hydrology & Earth System Sciences (2011), http://dx.doi.org/10.5194/hess-15-2913-2011 Sutanudjaja et al., Water Resources Research (2014a), http://dx.doi.org/10.1002/2013WR013807 Sutanudjaja et al., AGU Fall Meeting (2014b), see: http://globalhydrology.nl/models/pcr-globwb-2-0/ van Beek et al., Water Resources Research (2011), http://dx.doi.org/10.1029/2010WR009791

  4. Developing a high-resolution regional atmospheric reanalysis for Australia

    Science.gov (United States)

    White, Christopher; Fox-Hughes, Paul; Su, Chun-Hsu; Jakob, Dörte; Kociuba, Greg; Eisenberg, Nathan; Steinle, Peter; Harris, Rebecca; Corney, Stuart; Love, Peter; Remenyi, Tomas; Chladil, Mark; Bally, John; Bindoff, Nathan

    2017-04-01

    A dynamically consistent, long-term atmospheric reanalysis can be used to support high-quality assessments of environmental risk and likelihood of extreme events. Most reanalyses are presently based on coarse-scale global systems that are not suitable for regional assessments in fire risk, water and natural resources, amongst others. The Australian Bureau of Meteorology is currently working to close this gap by producing a high-resolution reanalysis over the Australian and New Zealand region to construct a sequence of atmospheric conditions at sub-hourly intervals over the past 25 years from 1990. The Australia reanalysis consists of a convective-scale analysis nested within a 12 km regional-scale reanalysis, which is bounded by a coarse-scale ERA-Interim reanalysis that provides the required boundary and initial conditions. We use an unchanging atmospheric modelling suite based on the UERRA system used at the UK Met Office and the more recent version of the Bureau of Meteorology's operational numerical prediction model used in ACCESS-R (Australian Community Climate and Earth-System Simulator-Regional system). An advanced (4-dimensional variational) data assimilation scheme is used to optimally combine model physics with multiple observations from aircrafts, sondes, surface observations and satellites to create a best estimate of state of the atmosphere over a 6-hour moving window. This analysis is in turn used to drive a higher-resolution (1.5 km) downscaling model over selected subdomains within Australia, currently eastern New South Wales and Tasmania, with the capability to support this anywhere in the Australia-New Zealand domain. The temporal resolution of the gridded analysis fields for both the regional and higher-resolution subdomains are generally one hour, with many fields such as 10 m winds and 2 m temperatures available every 10 minutes. The reanalysis also produces many other variables that include wind, temperature, moisture, pressure, cloud cover

  5. High resolution Ceres HAMO atlas derived from Dawn FC images

    Science.gov (United States)

    Roatsch, Thomas; Kersten, Elke; Matz, Klaus-Dieter; Preusker, Frank; Scholten, Frank; Jaumann, Ralf; Raymond, Carol A.; Russell, Chris T.

    2016-04-01

    Introduction: NASA's Dawn spacecraft entered the orbit of dwarf planet Ceres in March 2015, and will characterize the geology, elemental and mineralogical composition, topography, shape, and internal structure of Ceres. One of the major goals of the mission is a global mapping of Ceres. Data: The Dawn mission was mapping Ceres in HAMO (High Altitude Mapping Orbit, 1475 km altitude) between August and October 2015. The framing camera took about 2,600 clear filter images with a resolution of about 140 m/pixel during these cycles. The images were taken with different viewing angles and different illumination conditions. We selected images from one cycle (cycle #1) for the mosaicking process to have similar viewing and illumination conditions. Very minor gaps in the coverage were filled with a few images from cycle #2. Data Processing: The first step of the processing chain towards the cartographic products is to ortho-rectify the images to the proper scale and map projec-tion type. This process requires detailed information of the Dawn orbit and attitude data and of the topography of the targets. Both, improved orientation and a high-resolution shape model, are provided by stereo processing (bundle block adjustment) of the HAMO stereo image dataset [3]. Ceres's HAMO shape model was used for the calculation of the ray intersection points while the map projection itself was done onto the reference sphere of Ceres with a radius of 470 km. The final step is the controlled mosaicking) of all images to a global mosaic of Ceres, the so-called basemap. Ceres map tiles: The Ceres atlas was produced in a scale of 1:750,000 and consists of 15 tiles that conform to the quadrangle scheme proposed by Greeley and Batson [4]. A map scale of 1:750,000 guarantees a mapping at the highest available Dawn resolution in HAMO. The individual tiles were extracted from the global mosaic and reprojected. Nomenclature: The Dawn team proposed 81 names for geological features. By international

  6. Special issue on high-resolution optical imaging

    Science.gov (United States)

    Smith, Peter J. S.; Davis, Ilan; Galbraith, Catherine G.; Stemmer, Andreas

    2013-09-01

    The pace of development in the field of advanced microscopy is truly breath-taking, and is leading to major breakthroughs in our understanding of molecular machines and cell function. This special issue of Journal of Optics draws attention to a number of interesting approaches, ranging from fluorescence and imaging of unlabelled cells, to computational methods, all of which are describing the ever increasing detail of the dynamic behaviour of molecules in the living cell. This is a field which traditionally, and currently, demonstrates a marvellous interplay between the disciplines of physics, chemistry and biology, where apparent boundaries to resolution dissolve and living cells are viewed in ever more clarity. It is fertile ground for those interested in optics and non-conventional imaging to contribute high-impact outputs in the fields of cell biology and biomedicine. The series of articles presented here has been selected to demonstrate this interdisciplinarity and to encourage all those with a background in the physical sciences to 'dip their toes' into the exciting and dynamic discoveries surrounding cell function. Although single molecule super-resolution microscopy is commercially available, specimen preparation and interpretation of single molecule data remain a major challenge for scientists wanting to adopt the techniques. The paper by Allen and Davidson [1] provides a much needed detailed introduction to the practical aspects of stochastic optical reconstruction microscopy, including sample preparation, image acquisition and image analysis, as well as a brief description of the different variants of single molecule localization microscopy. Since super-resolution microscopy is no longer restricted to three-dimensional imaging of fixed samples, the review by Fiolka [2] is a timely introduction to techniques that have been successfully applied to four-dimensional live cell super-resolution microscopy. The combination of multiple high-resolution techniques

  7. Topography improvements in MEMS DMs for high-contrast, high-resolution imaging Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This project will develop and demonstrate an innovative microfabrication process to substantially improve the surface quality achievable in high-resolution...

  8. High resolution, high bandwidth global shutter CMOS area scan sensors

    Science.gov (United States)

    Faramarzpour, Naser; Sonder, Matthias; Li, Binqiao

    2013-10-01

    Global shuttering, sometimes also known as electronic shuttering, enables the use of CMOS sensors in a vast range of applications. Teledyne DALSA Global shutter sensors are able to integrate light synchronously across millions of pixels with microsecond accuracy. Teledyne DALSA offers 5 transistor global shutter pixels in variety of resolutions, pitches and noise and full-well combinations. One of the recent generations of these pixels is implemented in 12 mega pixel area scan device at 6 um pitch and that images up to 70 frames per second with 58 dB dynamic range. These square pixels include microlens and optional color filters. These sensors also offer exposure control, anti-blooming and high dynamic range operation by introduction of a drain and a PPD reset gate to the pixel. The state of the art sense node design of Teledyne DALSA's 5T pixel offers exceptional shutter rejection ratio. The architecture is consistent with the requirements to use stitching to achieve very large area scan devices. Parallel or serial digital output is provided on these sensors using on-chip, column-wise analog to digital converters. Flexible ADC bit depth combined with windowing (adjustable region of interest, ROI) allows these sensors to run with variety of resolution/bandwidth combinations. The low power, state of the art LVDS I/O technology allows for overall power consumptions of less than 2W at full performance conditions.

  9. High-resolution optimal quantization for stochastic pooling networks

    Science.gov (United States)

    McDonnell, Mark D.; Amblard, Pierre-Olivier; Stocks, Nigel G.; Zozor, Steeve; Abbott, Derek

    2007-01-01

    Pooling networks of noisy threshold devices are good models for natural networks (e.g. neural networks in some parts of sensory pathways in vertebrates, networks of mossy fibers in the hippothalamus, . . . ) as well as for artificial networks (e.g. digital beamformers for sonar arrays, flash analog-to-digital converters, rate-constrained distributed sensor networks, . . . ). Such pooling networks exhibit the curious effect of suprathreshold stochastic resonance, which means that an optimal stochastic control of the network exists. Recently, some progress has been made in understanding pooling networks of identical, but independently noisy, threshold devices. One aspect concerns the behavior of information processing in the asymptotic limit of large networks, which is a limit of high relevance for neuroscience applications. The mutual information between the input and the output of the network has been evaluated, and its extremization has been performed. The aim of the present work is to extend these asymptotic results to study the more general case when the threshold values are no longer identical. In this situation, the values of thresholds can be described by a density, rather than by exact locations. We present a derivation of Shannon's mutual information between the input and output of these networks. The result is an approximation that relies a weak version of the law of large numbers, and a version of the central limit theorem. Optimization of the mutual information is then discussed.

  10. Progress towards a high-resolution retinal prosthesis

    Science.gov (United States)

    Butterwick, Alex; Vankov, Alex; Huie, Phil; Vijayraghavan, Karthik; Loudin, Jim; Palanker, Daniel

    2007-02-01

    Electronic retinal prostheses represent a potentially effective approach for restoring some degree of sight in blind patients with retinal degeneration. Functional restoration of sight would require hundreds to thousands of electrodes effectively stimulating remaining neurons in the retina. We present a design of an optoelectronic retinal prosthetic system having 3mm diameter retinal implant with pixel sizes down to 25 micrometers, which allows for natural eye scanning for observing a large field of view, as well as spatial and temporal processing of the visual scene to optimize the patient experience. Information from a head mounted video camera is processed in a portable computer and delivered to the implanted photodiode array by projection from the LCD goggles using pulsed IR (810 nm) light. Each photodiode converts pulsed light (0.5 ms in duration) into electric current with efficiency of 0.3 A/W using common bi-phasic power line. Power is provided by the inductively-coupled RF link from the coil on the goggles into a miniature power supply implanted between the sclera and the conjuctiva, and connected to subretinal implant with a thin 2-wire trans-scleral cable. 3-dimensional structures in the subretinal prosthesis induce retinal migration and thus ensure close proximity between stimulating electrodes and the target retinal neurons. Subretinal implantations of the 3-dimentional pillar and chamber arrays in RCS rats with 2 and 6 week follow-up demonstrate achievement of intimate proximity between the stimulation cites and the inner nuclear layer. In some instances formation of a fibrotic seal has been observed.

  11. Development of high resolution imaging detectors for x ray astronomy

    Science.gov (United States)

    Murray, S. S.; Schwartz, D. A.

    1992-01-01

    This final report summarizes our past activities and discusses the work performed over the period of 1 April 1990 through 1 April 1991 on x-ray optics, soft x-ray (0.1 - 10 KeV) imaging detectors, and hard x-ray (10 - 300 KeV) imaging detectors. If microchannel plates (MCPs) can be used to focus x-rays with a high efficiency and good angular resolution, they will revolutionize the field of x-ray optics. An x-ray image of a point source through an array of square MCP pores compared favorably with our ray tracing model for the MCP. Initial analysis of this image demonstrates the feasibility of MCPs for soft x-rays. Our work continues with optimizing the performance of our soft x-ray MCP imaging detectors. This work involves readout technology that should provide improved MCP readout devices (thin film crossed grid, curved, and resistive sheets), defect removal in MCPs, and photocathode optimization. In the area of hard x-ray detector development we have developed two different techniques for producing a CsI photocathode thickness of 10 to 100 microns, such that it is thick enough to absorb the high energy x-rays and still allow the photoelectrons to escape to the top MCP of a modified soft x-ray imaging detector. The methods involve vacuum depositing a thick film of CsI on a strong back, and producing a converter device that takes the place of the photocathode.

  12. Vineyard Yield Estimation Based on the Analysis of High Resolution Images Obtained with Artificial Illumination at Night

    Directory of Open Access Journals (Sweden)

    Davinia Font

    2015-04-01

    Full Text Available This paper presents a method for vineyard yield estimation based on the analysis of high-resolution images obtained with artificial illumination at night. First, this paper assesses different pixel-based segmentation methods in order to detect reddish grapes: threshold based, Mahalanobis distance, Bayesian classifier, linear color model segmentation and histogram segmentation, in order to obtain the best estimation of the area of the clusters of grapes in this illumination conditions. The color spaces tested were the original RGB and the Hue-Saturation-Value (HSV. The best segmentation method in the case of a non-occluded reddish table-grape variety was the threshold segmentation applied to the H layer, with an estimation error in the area of 13.55%, improved up to 10.01% by morphological filtering. Secondly, after segmentation, two procedures for yield estimation based on a previous calibration procedure have been proposed: (1 the number of pixels corresponding to a cluster of grapes is computed and converted directly into a yield estimate; and (2 the area of a cluster of grapes is converted into a volume by means of a solid of revolution, and this volume is converted into a yield estimate; the yield errors obtained were 16% and −17%, respectively.

  13. High Resolution Simulation of a Colorado Rockies Extreme Snow and Rain Event in both a Current and Future Climate

    Science.gov (United States)

    Rasmussen, Roy; Ikeda, Kyoko; Liu, Changhai; Gutmann, Ethan; Gochis, David

    2016-04-01

    Modeling of extreme weather events often require very finely resolved treatment of atmospheric circulation structures in order to produce and localize the large moisture fluxes that result in extreme precipitation. This is particularly true for cool season orographic precipitation processes where the representation of the landform can significantly impact vertical velocity profiles and cloud moisture entrainment rates. This study presents results for high resolution regional climate modeling study of the Colorado Headwaters region using an updated version of the Weather Research and Forecasting (WRF) model run at 4 km horizontal resolution and a hydrological extension package called WRF-Hydro. Previous work has shown that the WRF modeling system can produce credible depictions of winter orographic precipitation over the Colorado Rockies if run at horizontal resolutions warming on total precipitation, snow-rain partitioning and surface hydrological fluxes (evapotranspiration and runoff) will be discussed in the context of how potential changes in temperature impact the amount of precipitation, the phase of precipitation (rain vs. snow) and the timing and amplitude of streamflow responses. The results show using the Pseudo Global Warming technique that intense precipitation rates significantly increased during the event and a significant fraction of the snowfall converts to rain which significantly amplifies the runoff response from one where runoff is produced gradually to one in which runoff is rapidly translated into streamflow values that approach significant flooding risks. Results from a new, CONUS scale high resolution climate simulation of extreme events in a current and future climate will be presented as time permits.

  14. High-resolution tree canopy mapping for New York City using LIDAR and object-based image analysis

    Science.gov (United States)

    MacFaden, Sean W.; O'Neil-Dunne, Jarlath P. M.; Royar, Anna R.; Lu, Jacqueline W. T.; Rundle, Andrew G.

    2012-01-01

    Urban tree canopy is widely believed to have myriad environmental, social, and human-health benefits, but a lack of precise canopy estimates has hindered quantification of these benefits in many municipalities. This problem was addressed for New York City using object-based image analysis (OBIA) to develop a comprehensive land-cover map, including tree canopy to the scale of individual trees. Mapping was performed using a rule-based expert system that relied primarily on high-resolution LIDAR, specifically its capacity for evaluating the height and texture of aboveground features. Multispectral imagery was also used, but shadowing and varying temporal conditions limited its utility. Contextual analysis was a key part of classification, distinguishing trees according to their physical and spectral properties as well as their relationships to adjacent, nonvegetated features. The automated product was extensively reviewed and edited via manual interpretation, and overall per-pixel accuracy of the final map was 96%. Although manual editing had only a marginal effect on accuracy despite requiring a majority of project effort, it maximized aesthetic quality and ensured the capture of small, isolated trees. Converting high-resolution LIDAR and imagery into usable information is a nontrivial exercise, requiring significant processing time and labor, but an expert system-based combination of OBIA and manual review was an effective method for fine-scale canopy mapping in a complex urban environment.

  15. High-resolution pixel detectors for second generation digital mammography

    Science.gov (United States)

    Tümer, Tümay O.; Yin, Shi; Cajipe, Victoria; Flores, Henry; Mainprize, James; Mawdsley, Gord; Rowlands, John A.; Yaffe, Martin J.; Gordon, Eli E.; Hamilton, William J.; Rhiger, David; Kasap, Safa O.; Sellin, Paul; Shah, Kanai S.

    2003-01-01

    Hybrid CdZnTe, CdTe, GaAs, selenium and PbI 2 pixel detector arrays with 50×50 μm 2 pixel sizes that convert X-rays directly into charge signals are under development at NOVA for application to digital mammography. These detectors have superior X-ray quantum efficiency compared to either emulsion-based film, phosphor-based detectors or other low-Z, solid-state detectors such as silicon. During this work, CdZnTe and CdTe pixel detectors gave the best results. The other detectors are at very early stages of development and need significant improvement. Among other detectors, selenium is showing the highest potential. The preliminary results show that single crystal CdZnTe detectors yield better results in Detective Quantum Efficiency (DQE) as well as in images obtained from phantoms, compared to the polycrystalline CdZnTe detectors. This is due to the non-uniformities in the polycrystaline CdZnTe that degrade the charge transport properties. In this paper, preliminary results from thin (0.15 to 0.2 mm) CdZnTe and CdTe detectors will be presented in terms of MTF, DQE and phantom images. Because of the charge-coupling limitation of the readout Application Specific Integrated Circuit (ASIC) that was originally designed for Si detectors, the detector is biased to collect holes from the input. This charge collection mode limits the CdZnTe detector performance. Their DQE measurements yield 25% and 65% for the polycrystal and single-crystal CdZnTe detectors, respectively. Polycrystal CdTe test detectors were also hybridized to the same type charge readout chip. Since CdTe has much longer hole-propagation lengths compared to CdZnTe, it shows better performance in the hole-collecting mode. However, it suffers from polarization. Excellent images were also obtained from the CdTe detectors. Future work to redesign the readout ASIC and thus improve the detector performance will be discussed. These detectors can also be used for other medical radiography with increased thickness

  16. High-resolution pixel detectors for second generation digital mammography

    Energy Technology Data Exchange (ETDEWEB)

    Tuemer, T.O. E-mail: tumay.tumer@novarad.com; Yin, Shi; Cajipe, Victoria; Flores, Henry; Mainprize, James; Mawdsley, Gord; Rowlands, John A.; Yaffe, Martin J.; Gordon, Eli E.; Hamilton, William J.; Rhiger, David; Kasap, Safa O.; Sellin, Paul; Shah, Kanai S

    2003-01-21

    Hybrid CdZnTe, CdTe, GaAs, selenium and PbI{sub 2} pixel detector arrays with 50x50 {mu}m{sup 2} pixel sizes that convert X-rays directly into charge signals are under development at NOVA for application to digital mammography. These detectors have superior X-ray quantum efficiency compared to either emulsion-based film, phosphor-based detectors or other low-Z, solid-state detectors such as silicon. During this work, CdZnTe and CdTe pixel detectors gave the best results. The other detectors are at very early stages of development and need significant improvement. Among other detectors, selenium is showing the highest potential. The preliminary results show that single crystal CdZnTe detectors yield better results in Detective Quantum Efficiency (DQE) as well as in images obtained from phantoms, compared to the polycrystalline CdZnTe detectors. This is due to the non-uniformities in the polycrystaline CdZnTe that degrade the charge transport properties. In this paper, preliminary results from thin (0.15 to 0.2 mm) CdZnTe and CdTe detectors will be presented in terms of MTF, DQE and phantom images. Because of the charge-coupling limitation of the readout Application Specific Integrated Circuit (ASIC) that was originally designed for Si detectors, the detector is biased to collect holes from the input. This charge collection mode limits the CdZnTe detector performance. Their DQE measurements yield 25% and 65% for the polycrystal and single-crystal CdZnTe detectors, respectively. Polycrystal CdTe test detectors were also hybridized to the same type charge readout chip. Since CdTe has much longer hole-propagation lengths compared to CdZnTe, it shows better performance in the hole-collecting mode. However, it suffers from polarization. Excellent images were also obtained from the CdTe detectors. Future work to redesign the readout ASIC and thus improve the detector performance will be discussed. These detectors can also be used for other medical radiography with

  17. High-Resolution X-ray Emission and X-ray Absorption Spectroscopy

    NARCIS (Netherlands)

    Groot, F.M.F. de

    2000-01-01

    In this review, high-resolution X-ray emission and X-ray absorption spectroscopy will be discussed. The focus is on the 3d transition-metal systems. To understand high-resolution X-ray emission and reso-nant X-ray emission, it is first necessary to spend some time discussing the X-ray absorption

  18. Quantifying geological processes on Mars - Results of the high resolution stereo camera (HRSC) on Mars express

    NARCIS (Netherlands)

    Jaumann, R.; Tirsch, D.; Hauber, E.; Ansan, V.; Di Achille, G.; Erkeling, G.; Fueten, F.; Head, J.; Kleinhans, M. G.|info:eu-repo/dai/nl/217675123; Mangold, N.; Michael, G. G.; Neukum, G.; Pacifici, A.; Platz, T.; Pondrelli, M.; Raack, J.; Reiss, D.; Williams, D. A.; Adeli, S.; Baratoux, D.; De Villiers, G.; Foing, B.; Gupta, S.; Gwinner, K.; Hiesinger, H.; Hoffmann, H.; Deit, L. Le; Marinangeli, L.; Matz, K. D.; Mertens, V.; Muller, J. P.; Pasckert, J. H.; Roatsch, T.; Rossi, A. P.; Scholten, F.; Sowe, M.; Voigt, J.; Warner, N.

    2015-01-01

    Abstract This review summarizes the use of High Resolution Stereo Camera (HRSC) data as an instrumental tool and its application in the analysis of geological processes and landforms on Mars during the last 10 years of operation. High-resolution digital elevations models on a local to regional scale

  19. Quantitation of Acrylamide in Foods by High-Resolution Mass Spectrometry

    NARCIS (Netherlands)

    Troise, A.D.; Fogliano, Vincenzo

    2016-01-01

    The use of liquid chromatography high-resolution mass spectrometry (LC-HRMS) and direct analysis real-time high-resolution mass spectrometry (DART-HRMS) defines a new scenario in the analysis of thermal-induced toxicants, such as acrylamide. Several factors contribute to the definition of the

  20. Spectral domain optical coherence tomography - Ultra-high speed, ultra-high resolution ophthalmic imaging

    NARCIS (Netherlands)

    Chen, T.; Cense, B.; Pierce, M. C.; Nassif, N. A.; Park, B. H.; Yun, S. H.; White, B.; Bouma, B. E.; Tearney, G. J.; de Boer, J.F.

    2005-01-01

    Objective: To introduce a new ophthalmic optical coherence tomography technology that allows unprecedented simultaneous ultra-high speed and ultra-high resolution. Methods: Using a superluminescent diode source, a clinically viable ultra-high speed, ultra-high resolution spectral domain optical

  1. Detection of proximal caries with high-resolution and standard resolution digital radiographic systems

    NARCIS (Netherlands)

    Berkhout, W.E.R.; Verheij, H.G.C.; Syriopoulos, K.; Li, G.; Sanderink, G.C.H.; van der Stelt, P.F.

    2007-01-01

    Aims: The aim of this study was to: (1) compare the diagnostic accuracy of the high-resolution and standard resolution settings of four digital imaging systems for caries diagnosis and (2) compare the effect on the diagnostic accuracy of reducing the high-resolution image sizes to the standard

  2. High-resolution CCD imagers using area-array CCD's for sensing spectral components of an optical line image

    Science.gov (United States)

    Elabd, Hammam (Inventor); Kosonocky, Walter F. (Inventor)

    1987-01-01

    CCD imagers with a novel replicated-line-imager architecture are abutted to form an extended line sensor. The sensor is preceded by optics having a slit aperture and having an optical beam splitter or astigmatic lens for projecting multiple line images through an optical color-discriminating stripe filter to the CCD imagers. A very high resolution camera suitable for use in a satellite, for example, is thus provided. The replicated-line architecture of the imager comprises an area-array CCD, successive rows of which are illuminated by replications of the same line segment, as transmitted by respective color filter stripes. The charge packets formed by accumulation of photoresponsive charge in the area-array CCD are read out row by row. Each successive row of charge packets is then converted from parallel to serial format in a CCD line register and its amplitude sensed to generate a line of output signal.

  3. A NEW HIGH RESOLUTION OPTICAL METHOD FOR OBTAINING THE TOPOGRAPHY OF FRACTURE SURFACES IN ROCKS

    Directory of Open Access Journals (Sweden)

    Steven Ogilvie

    2011-05-01

    Full Text Available Surface roughness plays a major role in the movement of fluids through fracture systems. Fracture surface profiling is necessary to tune the properties of numerical fractures required in fluid flow modelling to those of real rock fractures. This is achieved using a variety of (i mechanical and (ii optical techniques. Stylus profilometry is a popularly used mechanical method and can measure surface heights with high precision, but only gives a good horizontal resolution in one direction on the fracture plane. This method is also expensive and simultaneous coverage of the surface is not possible. Here, we describe the development of an optical method which images cast copies of rough rock fractures using in-house developed hardware and image analysis software (OptiProf™ that incorporates image improvement and noise suppression features. This technique images at high resolutions, 15-200 μm for imaged areas of 10 × 7.5 mm and 100 × 133 mm, respectively and a similar vertical resolution (15 μm for a maximum topography of 4 mm. It uses in-house developed hardware and image analysis (OptiProf™ software and is cheap and non-destructive, providing continuous coverage of the fracture surface. The fracture models are covered with dye and fluid thicknesses above the rough surfaces converted into topographies using the Lambert-Beer Law. The dye is calibrated using 2 devices with accurately known thickness; (i a polycarbonate tile with wells of different depths and (ii a wedge-shaped vial made from silica glass. The data from each of the two surfaces can be combined to provide an aperture map of the fracture for the scenario where the surfaces touch at a single point or any greater mean aperture. The topography and aperture maps are used to provide data for the generation of synthetic fractures, tuned to the original fracture and used in numerical flow modelling.

  4. Fast Binary Coding for the Scene Classification of High-Resolution Remote Sensing Imagery

    Directory of Open Access Journals (Sweden)

    Fan Hu

    2016-06-01

    Full Text Available Scene classification of high-resolution remote sensing (HRRS imagery is an important task in the intelligent processing of remote sensing images and has attracted much attention in recent years. Although the existing scene classification methods, e.g., the bag-of-words (BOW model and its variants, can achieve acceptable performance, these approaches strongly rely on the extraction of local features and the complicated coding strategy, which are usually time consuming and demand much expert effort. In this paper, we propose a fast binary coding (FBC method, to effectively generate efficient discriminative scene representations of HRRS images. The main idea is inspired by the unsupervised feature learning technique and the binary feature descriptions. More precisely, equipped with the unsupervised feature learning technique, we first learn a set of optimal “filters” from large quantities of randomly-sampled image patches and then obtain feature maps by convolving the image scene with the learned filters. After binarizing the feature maps, we perform a simple hashing step to convert the binary-valued feature map to the integer-valued feature map. Finally, statistical histograms computed on the integer-valued feature map are used as global feature representations of the scenes of HRRS images, similar to the conventional BOW model. The analysis of the algorithm complexity and experiments on HRRS image datasets demonstrate that, in contrast with existing scene classification approaches, the proposed FBC has much faster computational speed and achieves comparable classification performance. In addition, we also propose two extensions to FBC, i.e., the spatial co-occurrence matrix and different visual saliency maps, for further improving its final classification accuracy.

  5. High-resolution imaging of hypervelocity metal jets using advanced high-speed photographic techniques

    Energy Technology Data Exchange (ETDEWEB)

    Shaw, L.L.; Muelder, S.A.

    1995-08-29

    It is now possible to obtain high resolution sequential photographs of the initial formation and evolution of hypervelocity metal jets formed by shaped charge devices fired in air. Researchers have been frustrated by the high velocity of the jet material and the luminous sheath of hot gases cloaking the jet that made detailed observation of the jet body extremely difficult. The camera system that provides the photographs is a large format multi-frame electro-optic camera, referred to as an IC camera (IC stands for image converter), that utilizes electro-optic shuttering, monochromatic pulsed laser illumination and bandpass filtering to provide sequential pictures (in 3D if desired) with minimal degradation due to luminous air shocks or motion blur. The large format (75mm image plane), short exposure (15 ns minimum), ruby laser illumination and bandpass filtering (monochromatic illumination while excluding extraneous light) produces clear, sharp, images of the detailed surface structure of a metal shaped charge jet during early jet formation, elongation of the jet body, jet tip evolution and subsequent particulation (breakup) of the jet body. By utilizing the new camera system in conjunction with the more traditional rotating mirror high speed cameras, pulsed radiography, and electrical sensors, a maximum amount of, often unique, data can be extracted from a single experiment. This paper was intended primarily as an oral presentation. For purposes of continuity and simplicity in these proceedings, the authors have chosen to concentrate on the development of the IC camera system and its impact on the photography of high speed shaped chargejets.

  6. High-Resolution Dual-Comb Spectroscopy with Ultra-Low Noise Frequency Combs

    Science.gov (United States)

    Hänsel, Wolfgang; Giunta, Michele; Beha, Katja; Perry, Adam J.; Holzwarth, R.

    2017-06-01

    Dual-comb spectroscopy is a powerful tool for fast broad-band spectroscopy due to the parallel interrogation of thousands of spectral lines. Here we report on the spectroscopic analysis of acetylene vapor in a pressurized gas cell using two ultra-low noise frequency combs with a repetition rate around 250 MHz. Optical referencing to a high-finesse cavity yields a sub-Hertz stability of all individual comb lines (including the virtual comb lines between 0 Hz and the carrier) and permits one to pick a small difference of repetition rate for the two frequency combs on the order of 300 Hz, thus representing an optical spectrum of 100 THz (˜3300 \\wn) within half the free spectral range (125 MHz). The transmission signal is derived straight from a photodetector and recorded with a high-resolution spectrum analyzer or digitized with a computer-controlled AD converter. The figure to the right shows a schematic of the experimental setup which is all fiber-coupled with polarization-maintaining fiber except for the spectroscopic cell. The graph on the lower right reveals a portion of the recorded radio-frequency spectrum which has been scaled to the optical domain. The location of the measured absorption coincides well with data taken from the HITRAN data base. Due to the intrinsic linewidth of all contributing comb lines, each sampling point in the transmission graph corresponds to the probing at an optical frequency with sub-Hertz resolution. This resolution is maintained in coherent wavelength conversion processes such as difference-frequency generation (DFG), sum-frequency generation (SFG) or non-linear broadening (self-phase modulation), and is therefore easily transferred to a wide spectral range from the mid infrared up to the visible spectrum.

  7. Hi-C 2.0: An optimized Hi-C procedure for high-resolution genome-wide mapping of chromosome conformation.

    Science.gov (United States)

    Belaghzal, Houda; Dekker, Job; Gibcus, Johan H

    2017-07-01

    Chromosome conformation capture-based methods such as Hi-C have become mainstream techniques for the study of the 3D organization of genomes. These methods convert chromatin interactions reflecting topological chromatin structures into digital information (counts of pair-wise interactions). Here, we describe an updated protocol for Hi-C (Hi-C 2.0) that integrates recent improvements into a single protocol for efficient and high-resolution capture of chromatin interactions. This protocol combines chromatin digestion and frequently cutting enzymes to obtain kilobase (kb) resolution. It also includes steps to reduce random ligation and the generation of uninformative molecules, such as unligated ends, to improve the amount of valid intra-chromosomal read pairs. This protocol allows for obtaining information on conformational structures such as compartment and topologically associating domains, as well as high-resolution conformational features such as DNA loops. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. TES/Aura L1B Spectra Special Observation High Resolution V004

    Data.gov (United States)

    National Aeronautics and Space Administration — A L1B High Resolution granule consists of radiometrically calibrated spectra & associated NESR, observed at 0.025 cm-1 resolution for a Special Observation &...

  9. Identification of Uvaria sp by barcoding coupled with high-resolution melting analysis (Bar-HRM)

    National Research Council Canada - National Science Library

    Osathanunkul, M; Madesis, P; Ounjai, S; Pumiputavon, K; Somboonchai, R; Lithanatudom, P; Chaowasku, T; Wipasa, J; Suwannapoom, C

    2016-01-01

    .... One of the ways to save cost and time (by omitting the sequencing step) in species identification is to use available barcode data to design optimized primers for further analysis, such as high-resolution melting analysis (HRM...

  10. High-Resolution Geologic Mapping in Eastern Candor Chasma: 2017 Status Report

    Science.gov (United States)

    Okubo, C. H.; Gaither, T. A.

    2017-06-01

    This abstract summarizes current results and planned activities from an ongoing initiative to construct a series of high-resolution structural and geologic maps in the east Candor Chasma region of Valles Marineris, Mars.

  11. Studies of high resolution array processing algorithms for multibeam bathymetric applications

    Digital Repository Service at National Institute of Oceanography (India)

    Chakraborty, B.; Schenke, H.W.

    In this paper a study is initiated to observe the usefulness of directional spectral estimation techniques for underwater bathymetric applications. High resolution techniques like the Maximum Likelihood (ML) method and the Maximum Entropy (ME...

  12. High-resolution CT of airspace nodules in idiopathic pulmonary hemosiderosis

    Energy Technology Data Exchange (ETDEWEB)

    Engeler, C.E. [Minnesota Univ., Minneapolis, MN (United States). Dept. of Radiology

    1995-12-01

    We describe the radiographic findings of idiopathic pulmonary hemosiderosis in a 20-year-old patient and compare high-resolution CT findings with conventional CT and radiography. (orig.). With 2 figs.

  13. Estimated Depth Maps of the Northwestern Hawaiian Islands Derived from High Resolution IKONOS Satellite Imagery (Draft)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Estimated shallow-water, depth maps were produced using rule-based, semi-automated image analysis of high-resolution satellite imagery for nine locations in the...

  14. LIS 0.1 DEGREE VERY HIGH RESOLUTION GRIDDED LIGHTNING ANNUAL CLIMATOLOGY (VHRAC) V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The LIS 0.1 Degree Very High Resolution Gridded Lightning Annual Climatology (VHRAC) dataset consists of gridded annual climatologies of total lightning flash rates...

  15. LIS 0.1 DEGREE VERY HIGH RESOLUTION GRIDDED LIGHTNING FULL CLIMATOLOGY (VHRFC) V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The LIS 0.1 Degree Very High Resolution Gridded Lightning Full Climatology (VHRFC) dataset consists of gridded full climatologies of total lightning flash rates seen...

  16. LIS 0.1 DEGREE VERY HIGH RESOLUTION GRIDDED LIGHTNING MONTHLY CLIMATOLOGY (VHRMC) V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The LIS 0.1 Degree Very High Resolution Gridded Lightning Monthly Climatology (VHRMC) dataset consists of gridded monthly climatologies of total lightning flash...

  17. LIS 0.1 DEGREE VERY HIGH RESOLUTION GRIDDED LIGHTNING DIURNAL CLIMATOLOGY (VHRDC) V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The LIS 0.1 Degree Very High Resolution Gridded Lightning Diurnal Climatology (VHRDC) dataset consists of gridded diurnal climatologies of total lightning flash...

  18. LIS 0.1 DEGREE VERY HIGH RESOLUTION GRIDDED LIGHTNING SEASONAL CLIMATOLOGY (VHRSC) V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The LIS 0.1 Degree Very High Resolution Gridded Lightning Seasonal Climatology (VHRSC) dataset consists of gridded seasonal climatologies of total lightning flash...

  19. AVHRR Orbital Segment = NOAA's Advanced Very High Resolution Radiometer Files: 1992 - 2000

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The Advanced Very High Resolution Radiometer (AVHRR) data set is comprised of data collected by the AVHRR sensor and held in the archives of the USGS Earth Resources...

  20. Change detection studies in and around Kolleru Lake using high resolution data

    Digital Repository Service at National Institute of Oceanography (India)

    Rao, M.V.; Rao. K.H.; Ramana, I.V.; Sasamal, S.K.; Choudhury, S.B.; Bhan, S.K.

    under fish pond culture within the lake area using high resolution data from satellites. The changes that are occurred during the last ten years in Kolleru lake area have been studied. The digital base map covering the lake and surroundings...

  1. High Resolution, Radiation Tolerant Focal Plane Array for Lunar And Deep Space Applications Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Aerius Photonics and its partners propose the development of a high resolution, radiation hardened 3-D FLASH Focal Plane Array (FPA), with performance expected to be...

  2. Improving the Specificity of High Resolution Breast MRI by Optimizing Data Acquisition and Diagnostic Models

    National Research Council Canada - National Science Library

    Partridge, Savannah

    2000-01-01

    .... A high-resolution, three time-point, contrast-enhanced MR technique was optimized for image quality, breast coverage, and time efficiency, and over 200 patients were imaged prior to undergoing surgery...

  3. AVHRR Composites = Advanced Very High Resolution Radiometer U.S. Alaska: 1989 - Present

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Normalized Difference Vegetation Index (NDVI) Composites are produced from multiple Advanced Very High Resolution Radiometer (AVHRR) daily observations that have...

  4. Small-size, high-resolution angular displacement measurement technology based on an imaging detector.

    Science.gov (United States)

    Yu, Hai; Wan, Qiuhua; Lu, Xinran; Du, Yingcai; Yang, Shouwang

    2017-01-20

    It is challenging to design a photoelectric encoder that is small in size while ensuring it has sufficiently high resolution and accuracy. Traditional displacement measurement via the moiré fringe signal does not facilitate high resolution at small grate sizes; photoelectric and digital photo processing can significantly improve the angle measurement resolution over traditional techniques. The primary focus of this paper includes grating displacement coding and decoding, as well as the corresponding high-resolution subdivision and measurement error factors. A small-size absolute photographic encoder was designed (50 mm diameter) that exhibits resolution of 1.24'' (20 bit) with a standard deviation of error of 14.3''. The results presented here may provide a theoretical and technological foundation for further research on small-size, high-resolution photographic rotary encoders.

  5. Ultra-compact, High Resolution, LADAR system for 3D Imaging Project

    Data.gov (United States)

    National Aeronautics and Space Administration — SiWave proposes to develop an innovative, ultra-compact, high resolution, long range LADAR system to produce a 3D map of the exterior of any object in space such as...

  6. High Resolution Multispectral Flow Imaging of Cells with Extended Depth of Field Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Proposed is the development the extended depth of field (EDF) or confocal like imaging capabilities of a breakthrough multispectral high resolution imaging flow...

  7. Calcareous plankton high resolution bio-magnetostratigraphy for the Langhian of the mediterranean area

    NARCIS (Netherlands)

    Di Stefano, A.; Foresi, L.M.; Lirer, F.; Iaccarino, S.M.; Turco, E.; Amore, F.O.; Mazzei, R.; Morabito, S.; Salvatorini, G.; Aziz, H.A.

    2008-01-01

    High-resolution quantitative and qualitative analyses of the planktonic foraminifer and calcareous nannofossil content have been carried out on three Middle Miocene sections, from the Mediterranean area. Such sections (Cretaccio section, Tremiti Islands, Southern Italy; Moria section, Marche Region,

  8. UARS High Resolution Doppler Imager (HRDI) Level 3AT V001

    Data.gov (United States)

    National Aeronautics and Space Administration — The High Resolution Doppler Imager (HRDI) Level 3AT data product consists of daily, 65.536 second interval time-ordered vertical profiles of meridional and zonal...

  9. C-CAP Lanai 2005 era High Resolution Land Cover Metadata

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set consists of land derived from high resolution imagery and was analyzed according to the Coastal Change Analysis Program (C-CAP) protocol to determine...

  10. C-CAP Santa Cruz 2001 era High Resolution Land Cover Metadata

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset represents land cover for the San Lorenzo River basin in Santa Cruz County, California derived from high resolution imagery. The land cover features in...

  11. UARS High Resolution Doppler Imager (HRDI) Level 3AL V001

    Data.gov (United States)

    National Aeronautics and Space Administration — The High Resolution Doppler Imager (HRDI) Level 3AL data product consists of daily, 4 degree increment latitude-ordered vertical profiles of meridional and zonal...

  12. Coastal Change Analysis Program (C-CAP) High Resolution Land Cover and Change Data

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The NOAA Coastal Change Analysis Program (C-CAP) produces national standardized high resolution land cover and change products for the coastal regions of the U.S....

  13. High resolution imaging of the dolomite (104) cleavage surface by atomic force microscopy

    OpenAIRE

    Pina Martínez, Carlos Manuel; Pimentel, Carlos; García Merino, Marta

    2010-01-01

    In this paper we present high resolution atomic force microscopy (AFM) images of dolomite (104) cleavage surfaces immersed in pure water. These images show a rectangular lattice with surface unit cell dimensions in general agreement with those derived from the dolomite bulk structure. Furthermore, the twodimensional fast Fourier transform (2D-FFT) plots of the high resolution images exhibit a pattern of periodicities consistent with both the alternate orientation of the carbonate ...

  14. High-resolution IF-to-baseband sigma delta ADC for car radios

    CERN Document Server

    Silva, Paulo G R

    2008-01-01

    High-Resolution IF-to-Baseband SigmaDelta ADC for Car Radios addresses the theory, system level design and circuit implementation of a high-resolution continuous-time IF-to-baseband quadrature SigmaDelta ADC. The target application of this ADC is in AM/FM/IBOC car radios. The ADC achieves a dynamic range of 118dB, which eliminates the need for an IF VGA or AM channel filter in car radios.

  15. The Study of Land Use Classification Based on SPOT6 High Resolution Data

    OpenAIRE

    Wu Song; Jiang Qigang

    2016-01-01

    A method is carried out to quick classification extract of the type of land use in agricultural areas, which is based on the spot6 high resolution remote sensing classification data and used of the good nonlinear classification ability of support vector machine. The results show that the spot6 high resolution remote sensing classification data can realize land classification efficiently, the overall classification accuracy reached 88.79% and Kappa factor is 0.8632 which means that the classif...

  16. A High Resolution Clinical PET with Breast and Whole Body Transfigurations

    Science.gov (United States)

    2006-08-01

    continues to be difficult, whether the density is a result of fibrocystic diseases or young age. Accurate detection of very small breast tumors (2...DAMD17-02-1-0461 TITLE: A High Resolution Clinical PET with Breast and Whole Body Transfigurations PRINCIPAL INVESTIGATOR: Wai-Hoi...SUBTITLE 5a. CONTRACT NUMBER A High Resolution Clinical PET with Breast and Whole Body Transfigurations 5b. GRANT NUMBER DAMD17-02-1-0461

  17. Bronchiolitis obliterans in children with Stevens-Johnson syndrome: follow-up with high resolution CT

    Energy Technology Data Exchange (ETDEWEB)

    Kim, M.J. [Dept. of Diagnostic Radiology, Severance Hospital, Seoul (Korea, Republic of); Lee, K.Y. [Dept. of Pediatrics, Severance Hospital, Yonsei University Coll. of Medicine, Seoul (Korea, Republic of)

    1996-01-01

    About one third of children with Stevens-Johnson syndrome have pulmonary involvement. As a consequence of airway epithelial injury, bronchiolitis obliterans can occur in these patients. Two cases of Stevens-Johnson syndrome-associated bronchiolitis obliterans in children were diagnosed and followed by high resolution CT without open lung biopsy. Serial changes of high resolution CT features of bronchiolitis obliterans are discussed and the literature is reviewed. (orig.)

  18. High Resolution Optical Spectroscopy of the Classical Nova V5668 Sgr Showing the Presence of Lithium

    Science.gov (United States)

    Wagner, R. Mark; Woodward, Charles E.; Starrfield, Sumner; Ilyin, Ilya; Strassmeier, Klaus

    2018-01-01

    The classical nova (CN) V5668 Sgr was discovered on 2015 March 15.634 and initial optical spectra implied it was an Fe II-class CN. We obtained high resolution optical spectroscopy on 30 nights between 2015 April 3 and 2016 June 5 with the 2 x 8.4 m Large Binocular Telescope (LBT) and the 1.8 m Vatican Advanced Technology Telescope (VATT) using the Potsdam Echelle Polarimetric Spectroscopic Instrument (PEPSI). The spectra cover all or part of the 3830-9065 Å spectral region at a spectral resolution of up to 270,000 (1 km/s); the highest resolution currently available on any 8-10 m class telescope. The early spectra are dominated by emission lines of the Balmer and Paschen series of hydrogen, Fe II, Ca II, and Na I with P Cyg-type line profiles as well as emission lines of [O I]. Numerous interstellar lines and bands are readily apparent at high spectral resolution. The permitted line profiles show complex and dramatic variations in the multi-component P Cyg-type line profiles with time. We detect a weak blue-shifted absorption line at a velocity consistent with Li I 6708 Å when compared with the line profiles of Hβ, Fe II 5169 Å, and Na I D. This line is present in spectra obtained on 7 of 8 consecutive nights up to day 21 of the outburst; but absent on day 42 when it is evident that the ionization of the ejecta has significantly increased. The equivalent width of the line converted to a column density, and the resulting mass fraction, imply a significant enrichment of 7Li in the ejecta. 7Li is produced by the decay of unstable 7Be created during the thermonuclear runaway. The discovery of the resonance lines of 7Be II in the optical spectra of the recent CNe V339 Del, V2944 Oph, and V5668 Sgr by Tajitsu et al. (2016) and its subsequent decay to 7Li (half life of 53 days) suggests a significant enrichment of 7Li in the Galaxy from CNe is possible. Our observations of the Li I 6708 Å line in the early optical spectra of V5668 Sgr mark the second direct

  19. So Many Rockets - The Road to High Resolution Imaging in X-rays

    Science.gov (United States)

    Murray, Stephen S.

    2013-01-01

    When I first begin to work on new imaging detectors for X-ray Astronomy I was at AS&E and I worked with Leon Van Speybroeck and Ed Kellogg on a sounding rocket project. We starting by using a microchannel plate image intensifier to detect X-ray photons and convert them to flashes of light that were recorded on 35 mm film frames. Simultaneously there was a 16 mm star camera taking frames so we could tell where the X-rays were coming from. I spent about 6 years working on this payload, eventually becoming the PI and evolving the detector from a film readout to an electronic readout (the crossed grid charge detector) that was the basis for the Einstein, ROSAT and Chandra High Resolution Imagers and Cameras. We had a series of about 6 or so rocket flights culminating in the 1978 flight that actually worked. We detected three photons from Sco X1, and background data from that flight allowed us to set the detector front bias voltage to minimize non-X-ray background for the Einstein HRI. Just about everything that could go wrong on those rockets did go wrong, from a switch not closing to a rocket misfire, to pointing 180 degrees off target. But we learned something each flight and kept coming back to try again. The worse thing for me was having to stay up all night at White Sands in a small darkroom where I could avoid the night crawlers and scorpions that frightened me to death. Not to mention the daredevil helicopter pilots who flew us to the recovery site hugging the ground at top speed all the way there! None-the-less, in the end we succeeded in our goals, and there is nothing so exciting as watching your payload being launched at night (even it did mean sneaking out from the bunker to do it!). Thanks to NASA and the US Navy's White Sands USS Desert Ship (LLS-1; Land Locked Ship - 1) for all the support.

  20. High-resolution microendoscopy for esophageal cancer screening in China: A cost-effectiveness analysis.

    Science.gov (United States)

    Hur, Chin; Choi, Sung Eun; Kong, Chung Yin; Wang, Gui-Qi; Xu, Hong; Polydorides, Alexandros D; Xue, Li-Yan; Perzan, Katherine E; Tramontano, Angela C; Richards-Kortum, Rebecca R; Anandasabapathy, Sharmila

    2015-05-14

    To study the cost-effectiveness of high-resolution microendoscopy (HRME) in an esophageal squamous cell carcinoma (ESCC) screening program in China. A decision analytic Markov model of ESCC was developed. Separate model analyses were conducted for cohorts consisting of an average-risk population or a high-risk population in China. Hypothetical 50-year-old individuals were followed until age 80 or death. We compared three different strategies for both cohorts: (1) no screening; (2) standard endoscopic screening with Lugol's iodine staining; and (3) endoscopic screening with Lugol's iodine staining and an HRME. Model parameters were estimated from the literature as well as from GLOBOCAN, the Cancer Incidence and Mortality Worldwide cancer database. Health states in the model included non-neoplasia, mild dysplasia, moderate dysplasia, high-grade dysplasia, intramucosal carcinoma, operable cancer, inoperable cancer, and death. Separate ESCC incidence transition rates were generated for the average-risk and high-risk populations. Costs in Chinese currency were converted to international dollars (I$) and were adjusted to 2012 dollars using the Consumer Price Index. The main outcome measurements for this study were quality-adjusted life years (QALYs) and incremental cost-effectiveness ratio (ICER). For the average-risk population, the HRME screening strategy produced 0.043 more QALYs than the no screening strategy at an additional cost of I$646, resulting in an ICER of I$11808 per QALY gained. Standard endoscopic screening was weakly dominated. Among the high-risk population, when the HRME screening strategy was compared with the standard screening strategy, the ICER was I$8173 per QALY. For both the high-risk and average-risk screening populations, the HRME screening strategy appeared to be the most cost-effective strategy, producing ICERs below the willingness-to-pay threshold, I$23500 per QALY. One-way sensitivity analysis showed that, for the average-risk population

  1. NOAA high resolution sea surface winds data from Synthetic Aperture Radar (SAR) on the RADARSAT-2 satellite

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Synthetic Aperture Radar (SAR)-derived high resolution wind products are calculated from high resolution SAR images of normalized radar cross section (NRCS) of the...

  2. Wavelength converter technology

    DEFF Research Database (Denmark)

    Kloch, Allan; Hansen, Peter Bukhave; Poulsen, Henrik Nørskov

    1999-01-01

    Wavelength conversion is important since it ensures full flexibility of the WDM network layer. Progress in optical wavelength converter technology is reviewed with emphasis on all-optical wavelength converter types based on semiconductor optical amplifiers.......Wavelength conversion is important since it ensures full flexibility of the WDM network layer. Progress in optical wavelength converter technology is reviewed with emphasis on all-optical wavelength converter types based on semiconductor optical amplifiers....

  3. Wavelength converter technology

    DEFF Research Database (Denmark)

    Kloch, Allan; Hansen, Peter Bukhave; Poulsen, Henrik Nørskov

    1999-01-01

    Wavelength conversion is important since it ensures full flexibility of the WDM network layer. Progress in optical wavelength converter technology is reviewed with emphasis on air-optical wavelength converter types based on semiconductor optical amplifiers.......Wavelength conversion is important since it ensures full flexibility of the WDM network layer. Progress in optical wavelength converter technology is reviewed with emphasis on air-optical wavelength converter types based on semiconductor optical amplifiers....

  4. Technologies for converter topologies

    Science.gov (United States)

    Zhou, Yan; Zhang, Haiyu

    2017-02-28

    In some embodiments of the disclosed inverter topologies, an inverter may include a full bridge LLC resonant converter, a first boost converter, and a second boost converter. In such embodiments, the first and second boost converters operate in an interleaved manner. In other disclosed embodiments, the inverter may include a half-bridge inverter circuit, a resonant circuit, a capacitor divider circuit, and a transformer.

  5. Power Converters for Accelerators

    CERN Document Server

    Visintini, R.

    2015-06-15

    Particle accelerators use a great variety of power converters for energizing their sub-systems; while the total number of power converters usually depends on the size of the accelerator or combination of accelerators (including the experimental setup), the characteristics of power converters depend on their loads and on the particle physics requirements: this paper aims to provide an overview of the magnet power converters in use in several facilities worldwide.

  6. Application of Convolutional Neural Network in Classification of High Resolution Agricultural Remote Sensing Images

    Science.gov (United States)

    Yao, C.; Zhang, Y.; Zhang, Y.; Liu, H.

    2017-09-01

    With the rapid development of Precision Agriculture (PA) promoted by high-resolution remote sensing, it makes significant sense in management and estimation of agriculture through crop classification of high-resolution remote sensing image. Due to the complex and fragmentation of the features and the surroundings in the circumstance of high-resolution, the accuracy of the traditional classification methods has not been able to meet the standard of agricultural problems. In this case, this paper proposed a classification method for high-resolution agricultural remote sensing images based on convolution neural networks(CNN). For training, a large number of training samples were produced by panchromatic images of GF-1 high-resolution satellite of China. In the experiment, through training and testing on the CNN under the toolbox of deep learning by MATLAB, the crop classification finally got the correct rate of 99.66 % after the gradual optimization of adjusting parameter during training. Through improving the accuracy of image classification and image recognition, the applications of CNN provide a reference value for the field of remote sensing in PA.

  7. High-resolution computed tomography and histopathological findings in hypersensitivity pneumonitis: a pictorial essay

    Energy Technology Data Exchange (ETDEWEB)

    Torres, Pedro Paulo Teixeira e Silva; Moreira, Marise Amaral Reboucas; Silva, Daniela Graner Schuwartz Tannus; Moreira, Maria Auxiliadora do Carmo [Universidade Federal de Goias (UFG), Goiania, GO (Brazil); Gama, Roberta Rodrigues Monteiro da [Hospital do Cancer de Barretos, Barretos, SP (Brazil); Sugita, Denis Masashi, E-mail: pedroptstorres@yahoo.com.br [Anapolis Unievangelica, Anapolis, GO (Brazil)

    2016-03-15

    Hypersensitivity pneumonitis is a diffuse interstitial and granulomatous lung disease caused by the inhalation of any one of a number of antigens. The objective of this study was to illustrate the spectrum of abnormalities in high-resolution computed tomography and histopathological findings related to hypersensitivity pneumonitis. We retrospectively evaluated patients who had been diagnosed with hypersensitivity pneumonitis (on the basis of clinical-radiological or clinical-radiological-pathological correlations) and had undergone lung biopsy. Hypersensitivity pneumonitis is clinically divided into acute, subacute, and chronic forms; high-resolution computed tomography findings correlate with the time of exposure; and the two occasionally overlap. In the subacute form, centrilobular micronodules, ground glass opacities, and air trapping are characteristic high-resolution computed tomography findings, whereas histopathology shows lymphocytic inflammatory infiltrates, bronchiolitis, variable degrees of organizing pneumonia, and giant cells. In the chronic form, high-resolution computed tomography shows traction bronchiectasis, honeycombing, and lung fibrosis, the last also being seen in the biopsy sample. A definitive diagnosis of hypersensitivity pneumonitis can be made only through a multidisciplinary approach, by correlating clinical findings, exposure history, high-resolution computed tomography findings, and lung biopsy findings. (author)

  8. APPLICATION OF CONVOLUTIONAL NEURAL NETWORK IN CLASSIFICATION OF HIGH RESOLUTION AGRICULTURAL REMOTE SENSING IMAGES

    Directory of Open Access Journals (Sweden)

    C. Yao

    2017-09-01

    Full Text Available With the rapid development of Precision Agriculture (PA promoted by high-resolution remote sensing, it makes significant sense in management and estimation of agriculture through crop classification of high-resolution remote sensing image. Due to the complex and fragmentation of the features and the surroundings in the circumstance of high-resolution, the accuracy of the traditional classification methods has not been able to meet the standard of agricultural problems. In this case, this paper proposed a classification method for high-resolution agricultural remote sensing images based on convolution neural networks(CNN. For training, a large number of training samples were produced by panchromatic images of GF-1 high-resolution satellite of China. In the experiment, through training and testing on the CNN under the toolbox of deep learning by MATLAB, the crop classification finally got the correct rate of 99.66 % after the gradual optimization of adjusting parameter during training. Through improving the accuracy of image classification and image recognition, the applications of CNN provide a reference value for the field of remote sensing in PA.

  9. Fiber optic cable-based high-resolution, long-distance VGA extenders

    Science.gov (United States)

    Rhee, Jin-Geun; Lee, Iksoo; Kim, Heejoon; Kim, Sungjoon; Koh, Yeon-Wan; Kim, Hoik; Lim, Jiseok; Kim, Chur; Kim, Jungwon

    2013-02-01

    Remote transfer of high-resolution video information finds more applications in detached display applications for large facilities such as theaters, sports complex, airports, and security facilities. Active optical cables (AOCs) provide a promising approach for enhancing both the transmittable resolution and distance that standard copper-based cables cannot reach. In addition to the standard digital formats such as HDMI, the high-resolution, long-distance transfer of VGA format signals is important for applications where high-resolution analog video ports should be also supported, such as military/defense applications and high-resolution video camera links. In this presentation we present the development of a compressionless, high-resolution (up to WUXGA, 1920x1200), long-distance (up to 2 km) VGA extenders based on serialized technique. We employed asynchronous serial transmission and clock regeneration techniques, which enables lower cost implementation of VGA extenders by removing the necessity for clock transmission and large memory at the receiver. Two 3.125-Gbps transceivers are used in parallel to meet the required maximum video data rate of 6.25 Gbps. As the data are transmitted asynchronously, 24-bit pixel clock time stamp is employed to regenerate video pixel clock accurately at the receiver side. In parallel to the video information, stereo audio and RS-232 control signals are transmitted as well.

  10. Information Extraction of High Resolution Remote Sensing Images Based on the Calculation of Optimal Segmentation Parameters.

    Science.gov (United States)

    Zhu, Hongchun; Cai, Lijie; Liu, Haiying; Huang, Wei

    2016-01-01

    Multi-scale image segmentation and the selection of optimal segmentation parameters are the key processes in the object-oriented information extraction of high-resolution remote sensing images. The accuracy of remote sensing special subject information depends on this extraction. On the basis of WorldView-2 high-resolution data, the optimal segmentation parameters methodof object-oriented image segmentation and high-resolution image information extraction, the following processes were conducted in this study. Firstly, the best combination of the bands and weights was determined for the information extraction of high-resolution remote sensing image. An improved weighted mean-variance method was proposed andused to calculatethe optimal segmentation scale. Thereafter, the best shape factor parameter and compact factor parameters were computed with the use of the control variables and the combination of the heterogeneity and homogeneity indexes. Different types of image segmentation parameters were obtained according to the surface features. The high-resolution remote sensing images were multi-scale segmented with the optimal segmentation parameters. Ahierarchical network structure was established by setting the information extraction rules to achieve object-oriented information extraction. This study presents an effective and practical method that can explain expert input judgment by reproducible quantitative measurements. Furthermore the results of this procedure may be incorporated into a classification scheme.

  11. Dedicated mobile high resolution prostate PET imager with an insertable transrectal probe

    Science.gov (United States)

    Majewski, Stanislaw; Proffitt, James

    2010-12-28

    A dedicated mobile PET imaging system to image the prostate and surrounding organs. The imaging system includes an outside high resolution PET imager placed close to the patient's torso and an insertable and compact transrectal probe that is placed in close proximity to the prostate and operates in conjunction with the outside imager. The two detector systems are spatially co-registered to each other. The outside imager is mounted on an open rotating gantry to provide torso-wide 3D images of the prostate and surrounding tissue and organs. The insertable probe provides closer imaging, high sensitivity, and very high resolution predominately 2D view of the prostate and immediate surroundings. The probe is operated in conjunction with the outside imager and a fast data acquisition system to provide very high resolution reconstruction of the prostate and surrounding tissue and organs.

  12. Diagnosis of ossicular chain in the middle ear by high-resolution CT

    Energy Technology Data Exchange (ETDEWEB)

    Fuse, Takeo (Hanamaki-Kosei Hospital, Iwate (Japan)); Aoyagi, Masaru; Koike, Yoshio; Sugai, Yukio

    1992-02-01

    This study was conducted to assess the usefulness and limitation of high-resolution CT for evaluating the condition of ossicular chain in the middle ear. Preoperative CT findings of the ossicular chain were compared with the operative findings of ossicles in 26 patients with chronic otitis media or congenital ossicular anomaly who underwent tympanoplasty. Total defect of head of the malleus, body of the incus and long process of the incus were completely detected by high-resolution CT. But the reliability in detecting the defect of handle of the malleus and superstructure of the stapes were 33.3% and 60%, respectively. Defect of the I-S joint (1 case) and partial defect of stapes crus (2 cases) could not be diagnosed correctly in the preoperative estimation. Although these findings demonstrate the limitations of high-resolution CT in the diagnosis of ossicular chain, it will be diminished by the advanced space resolution of CT in the future. (author).

  13. Application of high-resolution MS for development of peptide and large-molecule drug candidates.

    Science.gov (United States)

    Kellie, John F; Kehler, Jonathan R; Szapacs, Matthew E

    2016-02-01

    For quantitative bioanalysis utilizing MS, the instrument of choice is typically a triple quadruple mass spectrometer. However, advances in high-resolution MS have allowed sensitivity and dynamic ranges to approach that of triple quadrupole instruments. A matrix-free protein digest, a digested therapeutic protein and the intact peptide therapeutic liraglutide were each analyzed on high-resolution and triple quadrupole mass spectrometers with data compared. Samples from a mouse PK study with liraglutide were analyzed using the two different instruments, and equivalent PK exposure data were demonstrated. High-resolution and triple quadrupole mass spectrometers can generate data resulting in identical PK parameters from an in-life sample set, thus giving confidence in either technique in support of biotherapeutic PK exposure studies.

  14. The impact of high-resolution ultrasound in the differential diagnosis of non-hemolytic jaundice.

    Science.gov (United States)

    Rauh, Peter; Neye, Holger; Mönkemüller, Klaus; Malfertheiner, Peter; Rickes, Steffen

    2010-12-01

    Because jaundice is a common reason for hospital admission. A fast and correct differential diagnosis is very important to increase treatment efficacy. The aim of our study was to evaluate the impact of the high-resolution ultrasound in this kind of clinical setting. In a prospective study we included 30 patients and we divided them in patients with extrahepatic jaundice and patients with intrahepatic jaundice. We observed a high accuracy of the high-resolution sonography, with a sensitivity of 95% and a specificity of 100% for extrahepatic jaundice, and a sensitivity of 100% and a specificity of 95% for intrahepatic jaundice. We conclude that the high-resolution ultrasound should be used in the very beginning of the diagnostic algorithm for the evaluation of patients with unclear jaundice.

  15. High Resolution Full-Aperture ISAR Processing through Modified Doppler History Based Motion Compensation.

    Science.gov (United States)

    Song, Jung-Hwan; Lee, Kee-Woong; Lee, Woo-Kyung; Jung, Chul-Ho

    2017-05-28

    A high resolution inverse synthetic aperture radar (ISAR) technique is presented using modified Doppler history based motion compensation. To this purpose, a novel wideband ISAR system is developed that accommodates parametric processing over extended aperture length. The proposed method is derived from an ISAR-to-SAR approach that makes use of high resolution spotlight SAR and sub-aperture recombination. It is dedicated to wide aperture ISAR imaging and exhibits robust performance against unstable targets having non-linear motions. We demonstrate that the Doppler histories of the full aperture ISAR echoes from disturbed targets are efficiently retrieved with good fitting models. Experiments have been conducted on real aircraft targets and the feasibility of the full aperture ISAR processing is verified through the acquisition of high resolution ISAR imagery.

  16. High Resolution Full-Aperture ISAR Processing through Modified Doppler History Based Motion Compensation

    Directory of Open Access Journals (Sweden)

    Jung-Hwan Song

    2017-05-01

    Full Text Available A high resolution inverse synthetic aperture radar (ISAR technique is presented using modified Doppler history based motion compensation. To this purpose, a novel wideband ISAR system is developed that accommodates parametric processing over extended aperture length. The proposed method is derived from an ISAR-to-SAR approach that makes use of high resolution spotlight SAR and sub-aperture recombination. It is dedicated to wide aperture ISAR imaging and exhibits robust performance against unstable targets having non-linear motions. We demonstrate that the Doppler histories of the full aperture ISAR echoes from disturbed targets are efficiently retrieved with good fitting models. Experiments have been conducted on real aircraft targets and the feasibility of the full aperture ISAR processing is verified through the acquisition of high resolution ISAR imagery.

  17. Theoretical analysis of microring resonator-based biosensor with high resolution and free of temperature influence

    Science.gov (United States)

    Jian, Aoqun; Zou, Lu; Tang, Haiquan; Duan, Qianqian; Ji, Jianlong; Zhang, Qianwu; Zhang, Xuming; Sang, Shengbo

    2017-06-01

    The issue of thermal effects is inevitable for the ultrahigh refractive index (RI) measurement. A biosensor with parallel-coupled dual-microring resonator configuration is proposed to achieve high resolution and free thermal effects measurement. Based on the coupled-resonator-induced transparency effect, the design and principle of the biosensor are introduced in detail, and the performance of the sensor is deduced by simulations. Compared to the biosensor based on a single-ring configuration, the designed biosensor has a 10-fold increased Q value according to the simulation results, thus the sensor is expected to achieve a particularly high resolution. In addition, the output signal of the mathematical model of the proposed sensor can eliminate the thermal influence by adopting an algorithm. This work is expected to have great application potentials in the areas of high-resolution RI measurement, such as biomedical discoveries, virus screening, and drinking water safety.

  18. High-resolution NMR and diffusion-ordered spectroscopy of port wine.

    Science.gov (United States)

    Nilsson, Mathias; Duarte, Iola F; Almeida, Cláudia; Delgadillo, Ivonne; Goodfellow, Brian J; Gil, Ana M; Morris, Gareth A

    2004-06-16

    The use of high-resolution NMR and high-resolution diffusion-ordered spectroscopy (DOSY) for the characterization of selected Port wine samples of different ages with the aim of identifying changes in composition is described. Conventional 1D and 2D NMR methods enabled the identification of about 35 compounds, including minor components such as some medium-chain alcohols, amino acids, and organic acids. High-resolution (HR) DOSY extended sample characterization, increasing the number of compounds identified and NMR assignments made, by providing information on the relative molecular sizes of the metabolites present. Port wines of different ages were found to differ mainly in their content of (a) organic acids and some amino acids, (b) an unidentified possible disaccharide, and (c) large aromatic species. The relative amount of these last high Mw aromatics is seen to decrease significantly in the oldest wine, as expected from the known formation and precipitation of anthocyanin-based polymers during red wine aging.

  19. Automated work-flow for processing high-resolution direct infusion electrospray ionization mass spectral fingerprints

    DEFF Research Database (Denmark)

    Hansen, Michael Adsetts Edberg; Smedsgaard, Jørn

    2007-01-01

    an automated data processing pipeline to compare large numbers of fingerprint spectra from direct infusion experiments analyzed by high resolution MS. We describe some of the intriguing problems that have to be addressed. starting with the conversion and pre-processing of the raw data to the final data...... analysis. Illustrated on the direct infusion analysis (ESI-TOF-MS) of complex mixtures the method exploits the full quality of the high-resolution present in the mass spectra. Although the method is illustrated as a new library search method for high resolution MS, we demonstrate that the output...... of the preprocessing is applicable to cluster-, discriminant analysis, and related multivariate methods applied directly to mass spectra from direct infusion analysis of crude extracts. This is done to find the relationship between several terverticillate Penicillium species and identify the ions responsible...

  20. Correlation between high-resolution computed tomography and surgical findings in congenital aural atresia.

    Science.gov (United States)

    Mehra, Y N; Dubey, S P; Mann, S B; Suri, S

    1988-02-01

    Congenital aural atresia poses a great challenge, even to a competent otologic surgeon, due to innumerable types of malformations affecting the conduction and perception of sound. Roentgenographic evaluation by plain roentgenography is inconclusive in most cases; polytomography is helping to some extent. Recent generations of high-resolution computed tomographic (CT) scanners are probably the best. Seven cases of unilateral and three cases of bilateral congenital aural atresia were evaluated with high-resolution CT. Subsequently, ten ears were operated on. Surgical findings were correlated with CT scan findings with respect to atresia plate, extent of pneumatization, ossicular anomalies, bony facial nerve canal, and inner ear. Use of CT scans bears considerable importance in the management of these types of cases. High-resolution CT scan, when targeted for maximal bony detail, is possibly the method of choice in congenital aural atresia when surgical correction is contemplated.

  1. High-resolution land/ice imaging using Seasat scatterometer measurements

    Science.gov (United States)

    Long, D. G.; Whiting, P. T.; Hardin, P. J.

    1992-01-01

    A new method for obtaining high-resolution images (to 4 km) of the land backscatter from low-resolution Seasat-A scatterometer (SASS) measurements is introduced. The method utilizes the measurement cell overlap in multiple spacecraft passes over the region of interest and signal processing techniques to generate high-resolution images of the radar backscatter. The overlap is exploited to estimate the underlying high-resolution surface radar backscatter characteristics using a robust multivariate image reconstruction algorithm. The algorithm has been designed to operate in the high-noise environment typical of scatterometer measurements. The ultimate resolution obtainable is a function of the number of measurements and the measurement overlap. Sample results based on SASS data are provided.

  2. High-resolution mirror temperature mapping in GaN-based diode lasers by thermoreflectance spectroscopy

    Science.gov (United States)

    Pierścińska, Dorota; Marona, Łucja; Pierściński, Kamil; Wiśniewski, Przemysław; Perlin, Piotr; Bugajski, Maciej

    2017-02-01

    In this paper accurate measurements of temperature distribution on the facet of GaN-based diode lasers are presented as well as development of the instrumentation for high-resolution thermal imaging based on thermoreflectance. It is shown that thermoreflectance can be successfully applied to provide information on heat dissipation in these devices. We demonstrate the quantitative measurements of the temperature profiles and high-resolution temperature maps on the front facet of nitride lasers and prove that thermoreflectance spectroscopy can be considered as the accurate and fast nondestructive tool for investigation of thermally induced degradation modes of GaN lasers.

  3. High-resolution two-dimensional image upconversion of incoherent light

    DEFF Research Database (Denmark)

    Dam, Jeppe Seidelin; Pedersen, Christian; Tidemand-Lichtenberg, Peter

    2010-01-01

    We consider a technique for high-resolution image upconversion of thermal light. Experimentally, we demonstrate cw upconversion with a resolution of more than 200 × 1000 pixels of thermally illuminated objects. This is the first demonstration (to our knowledge) of high-resolution cw image...... upconversion. The upconversion method promises an alternative route to high-quantum-efficiency all-optical imaging in the mid-IR wavelength region and beyond using standard CCD cameras. A particular advantage of CCD cameras compared to state-of-the-art thermal cameras is the possibility to tailor and tune...... the spectral response leading to functional spectral imaging....

  4. Towards high resolution polarisation analysis using double polarisation and ellipsoidal analysers

    CERN Document Server

    Martin-Y-Marero, D

    2002-01-01

    Classical polarisation analysis methods lack the combination of high resolution and high count rate necessary to cope with the demand of modern condensed-matter experiments. In this work, we present a method to achieve high resolution polarisation analysis based on a double polarisation system. Coupling this method with an ellipsoidal wavelength analyser, a high count rate can be achieved whilst delivering a resolution of around 10 mu eV. This method is ideally suited to pulsed sources, although it can be adapted to continuous sources as well. (orig.)

  5. Ultra high resolution molecular beam cars spectroscopy with application to planetary atmospheric molecules

    Science.gov (United States)

    Byer, R. L.

    1982-01-01

    The measurement of high resolution pulsed and continuous wave (CW) coherent anti-Stokes Raman spectroscopy (CARS) measurements in pulsed and steady state supersonic expansions were demonstrated. Pulsed molecular beam sources were characterized, and saturation of a Raman transition and, for the first time, the Raman spectrum of a complex molecular cluster were observed. The observation of CW CARS spectra in a molecular expansion and the effects of transit time broadening is described. Supersonic expansion is established as a viable technique for high resolution Raman spectroscopy of cold molecules with resolutions of 100 MH2.

  6. High-resolution full-field spatial coherence gated optical tomography using monochromatic light source

    Science.gov (United States)

    Srivastava, Vishal; Nandy, Sreyankar; Singh Mehta, Dalip

    2013-09-01

    We demonstrate dispersion free, high-resolution full-field spatial coherence gated optical tomography using spatially incoherent monochromatic light source. Spatial coherence properties of light source were synthesized by means of combining a static diffuser and vibrating multi mode fiber bundle. Due to low spatial coherence of light source, the axial resolution of the system was achieved similar to that of conventional optical coherence tomography which utilizes low temporal coherence. Experimental results of fringe visibility versus optical path difference are presented for varying numerical apertures objective lenses. High resolution optically sectioned images of multilayer onion skin, and red blood cells are presented.

  7. Sharp or broad pulse peak for high resolution instruments? Choice of moderator performance

    Energy Technology Data Exchange (ETDEWEB)

    Arai, M. [High Energy Accelerator Research Organization, Tsukuba, Ibaraki (Japan); Watanabe, N.; Teshigawara, M. [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment] [and others

    2001-03-01

    We demonstrate a concept how we should choose moderator performance to realize required performance for instruments. Neutron burst pulse can be characterized with peak intensity, peak width and tail. Those can be controllable by designing moderator, i.e. material, temperature, shape, decoupling, poisoning and having premoderator. Hence there are large number of variable parameters to be determined. Here we discuss the required moderator performance for some typical examples, i.e. high resolution powder instrument, chopper instrument, high resolution back scattering machine. (author)

  8. In-situ investigations of structural changes during cyclic loading by high resolution reciprocal space mapping

    DEFF Research Database (Denmark)

    Diederichs, Annika M.; Thiel, Felix; Lienert, Ulrich

    2017-01-01

    dislocation structures can be identified using advanced electron microscopy and synchrotron techniques. A detailed characterization of the microstructure during cyclic loading by in-situ monitoring the internal structure within individual grains with high energy x-rays can help to understand and predict...... the materials behavior during cyclic deformation and to improve the material design. While monitoring macroscopic stress and strain during cyclic loading, reciprocal space maps of diffraction peaks from single grains are obtained with high resolution. High Resolution Reciprocal Space Mapping was applied...

  9. Real-time underwater object detection based on an electrically scanned high-resolution sonar

    DEFF Research Database (Denmark)

    Henriksen, Lars

    1994-01-01

    The paper describes an approach to real time detection and tracking of underwater objects, using image sequences from an electrically scanned high-resolution sonar. The use of a high resolution sonar provides a good estimate of the location of the objects, but strains the computers on board......, because of the high rate of raw data. The amount of data can be cut down by decreasing the scanned area, but this reduces the possibility of planning an optimal path. In the paper methods are described, that maintains the wide area of detection, without significant loss of precision or speed. This is done...

  10. An interferometer for high-resolution optical surveillance from geostationary orbit

    Science.gov (United States)

    Bonino, L.; Bresciani, F.; Piasini, G.; Flebus, C.; Lecat, J.-H.; Roose, S.; Pisani, M.; Cabral, A.; Rebordão, J.; Proença, C.; Costal, J.; Lima, P. U.; Loix, N.; Musso, F.

    2017-11-01

    The activities described in this paper have been developed in the frame of the EUCLID CEPA 9 RTP 9.9 "High Resolution Optical Satellite Sensor" project of the WEAO Research Cell. They have been focused on the definition of an interferometric instrument optimised for the high-resolution optical surveillance from geostationary orbit (GEO) by means of the synthetic aperture technique, and on the definition and development of the related enabling technologies. In this paper we describe the industrial team, the selected mission specifications and overview of the whole design and manufacturing activities performed.

  11. Diagnosis of Type-I hiatal hernia: a comparison of high-resolution manometry and endoscopy.

    Science.gov (United States)

    Khajanchee, Y S; Cassera, M A; Swanström, L L; Dunst, C M

    2013-01-01

    Sliding Type-I hiatal hernia is commonly diagnosed using upper endoscopy, barium swallow or less commonly, esophageal manometry. Current data suggest that endoscopy is superior to barium swallow or esophageal manometry. Recently, high-resolution manometry has become available for the assessment of esophageal motility. This novel technology is capable of displaying spatial and topographic pressure profiles of gastroesophageal junction and crural diaphragm in real time. The objective of the current study was to compare the specificity and sensitivity of high-resolution manometry and endoscopy in the diagnosis of sliding hiatal hernia in patients with gastroesophageal reflux disease. Data were analyzed retrospectively for 83 consecutive patients (61% females, mean age 52 ± 13.2 years) with objective gastroesophageal reflux disease who were considered for laparoscopic antireflux surgery between January 2006 and January 2009 and had preoperative high-resolution manometry and endoscopy. Manometrically, hiatal hernia was defined as separation of the gastroesophageal junction >2.0 cm from the crural diaphragm. Intraoperative diagnosis of hiatal hernia was used as the gold standard. Sensitivity, specificity and likelihood ratios of a positive test and a negative test were used to compare the performance of the two diagnostic modalities. Forty-two patients were found to have a Type-I sliding hiatal hernia (>2 cm) during surgery. Twenty-two patients had manometric criteria for a hiatal hernia by high-resolution manometry, and 36 patients were described as having a hiatal hernia by preoperative endoscopy. False positive results were significantly fewer (higher specificity) with high-resolution manometry as compared with endoscopy (4.88% vs. 31.71%, P= 0.01). There were no significant differences in the false negative results (sensitivity) between the two diagnostic modalities (47.62% vs. 45.24%, P= 0.62). Analysis of likelihood ratios of a positive and negative test

  12. High-resolution XAS/XES analyzing electronic structures of catalysts

    CERN Document Server

    Sa, Jacinto

    2014-01-01

    Photon-in-photon-out core level spectroscopy is an emerging approach to characterize the electronic structure of catalysts and enzymes, and it is either installed or planned for intense synchrotron beam lines and X-ray free electron lasers. This type of spectroscopy requires high-energy resolution spectroscopy not only for the incoming X-ray beam but also, in most applications, for the detection of the outgoing photons. Thus, the use of high-resolution X-ray crystal spectrometers whose resolving power ?E/E is typically about 10-4, is mandatory.High-Resolution XAS/XES: Analyzing Electronic Stru

  13. High-resolution nanopatterning of biodegradable polylactide by thermal nanoimprint lithography using gas permeable mold

    Science.gov (United States)

    Takei, Satoshi; Hanabata, Makoto

    2017-03-01

    We report high-resolution (150 nm) nanopatterning of biodegradable polylactide by thermal nanoimprint lithography using dichloromethane as a volatile solvent for improving the liquidity and a porous cyclodextrin-based gas-permeable mold. This study demonstrates the high-resolution patterning of polylactic acid and other non-liquid functional materials with poor fluidity by thermal nanoimprinting. Such a patterning is expected to expand the utility of thermal nanoimprint lithography and fabricate non-liquid functional materials suitable for eco-friendly and biomedical applications.

  14. High-resolution CT findings in Wilson-Mikity syndrome: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Reittner, P.; Fotter, R.; Tillich, M.; Lindbichler, F. [Division of Paediatric Radiology, University Hospital Graz (Austria); Popper, H. [Department of Pathology, University Hospital Graz (Austria); Reiterer, F. [Department of Paediatrics, University Hospital Graz (Austria)

    1998-09-01

    Wilson-Mikity syndrome (WMS), an uncommon cause of respiratory distress presenting after birth, is radiologically characterised by varying degrees of interstitial thickening and bilateral cyst-like foci of hyperinflation. Aetiology and pathogenesis are still unknown. There are few reports of WMS in the paediatric literature and none describing the features and value of high-resolution CT. The purpose of this report is to describe the radiographic findings and high-resolution CT appearance of WMS and to correlate them with the histopathological findings. (orig.) With 3 figs., 6 refs.

  15. Frequency combs enable rapid and high-resolution multidimensional coherent spectroscopy

    Science.gov (United States)

    Lomsadze, Bachana; Cundiff, Steven T.

    2017-09-01

    Dual laser frequency combs can rapidly measure high-resolution linear absorption spectra. However, one-dimensional linear techniques cannot distinguish the sources of resonances in a mixture of different analytes, nor can they separate inhomogeneous and homogeneous broadening. Here, we overcame these limitations by acquiring high-resolution multidimensional nonlinear coherent spectra with frequency combs. We experimentally differentiated and assigned the Doppler-broadened features of two naturally occurring isotopes of rubidium atoms (87Rb and 85Rb) according to the placement of their hyperfine energy states in a two-dimensional spectrum.

  16. Parametric algorithms for frequency estimation in PWM converter systems

    Energy Technology Data Exchange (ETDEWEB)

    Lobos, T.; Hejke, I.; Rezmer, J.; Sikorski, T.; Kostyla, P. [Dept. of Electrical Engineering, Wroclaw University of Technology, Wyb. Wyspianskiego 27, 50-370 Wroclaw (Poland)

    2009-11-15

    Proper estimation of voltage parameters has a significant meaning for power converters control systems. One of the measured parameter, directly associated with control process, is frequency of the basic voltage component at the converter output. Unfortunately, power converters generate a wide spectrum of harmonics as well as interharmonics, that makes difficulties in estimation this frequency. Measurement carried out in industrial applications exhibits complex nature of investigated signals often corrupted by resonances or overvoltages phenomena. It entails searching a new digital algorithms for frequency measurement. This work presents algorithm using modification of high-resolution Prony method connected with digital filtering. The investigations was based on simulations and real measured signals recorded in two different commercial PWM converters. Obtained results indicate accuracy of the method as well as its fast response. (author)

  17. A Low-Cost and High-Resolution Droplet Position Detector for an Intelligent Electrowetting on Dielectric Device.

    Science.gov (United States)

    Li, Yiyan; Li, Hongzhong; Baker, R Jacob

    2015-12-01

    A low-cost and high-resolution capacitive-to-digital converter integrated circuit is used for droplet position detection in a digital microfluidic system. A field-programmable gate array FPGA is used as the integrated logic hub of the system for a highly reliable and efficient control of the circuit. A fast-fabricating PCB (printed circuit board) substrate microfluidic system is proposed. Smaller actuation threshold voltages than those previously reported are obtained. Droplets (3 µL) are actuated by using a 200 V, 500 Hz modulating pulsed voltage. Droplet positions can be detected and displayed on a PC-based 3D animation in real time. The actuators and the capacitance sensing circuits are implemented on one PCB to reduce the size of the system. With the capacitive droplet position detection system, the PCB-based electrowetting on dielectric device (EWOD) reported in this work has promise in automating immunohistochemistry experiments. © 2015 Society for Laboratory Automation and Screening.

  18. Retrieval of Atmospheric CO2 and CH4 Variations Using Ground-Based High Resolution Fourier Transform Infrared Spectra

    Directory of Open Access Journals (Sweden)

    Tian Yuan

    2015-01-01

    Full Text Available High resolution Fourier transform near IR solar spectra are used to estimate the column-averaged dry-air mole fraction (DMF of CO2 and CH4 variations in the atmosphere. The preliminary retrieval results for CO2 and CH4 variations in the area of Hefei, China, are presented, and the underlying error sources are also analyzed. Both a forward analysis and an inversion algorithm are included in the retrieval. The forward analysis uses the modeled atmospheric transmittance to line-by-line (LBL convolute the instrument line shape function. The influences of the temperature, pressure, humidity, and a priori gases are considered in the atmospheric transmittance model. The inversion algorithm is based on the nonlinear iterative and nonlinear least squares spectral fitting, which is used to obtain VCDCO2 and VCDCH4 (which represent vertical column density of CO2 and CH4, resp.. Furthermore, the VCDO2 is also retrieved for converting the VCDs into DMFs. DMFs are final products of data analysis. The inversion results can clearly resolve the tiny variations of CO2 and CH4 under strong atmospheric background. Spectral fitting residuals for both VCDCO2 and VCDCH4 are less than 0.5%. Finally, CO2 and CH4 diurnal variations are investigated based on a typical observation. About 2 ppm amplitude for DMFCO2 diurnal variations and less than 15 ppb amplitude for DMFCH4 are observed.

  19. Power converters definitions, classification and converter topologies

    CERN Document Server

    Bordry, Frederick

    2006-01-01

    This paper introduces power conversion principles and defines the terminology. The concepts of sources and switches are defined and classified. From the basic laws of source interconnections, a generic method of power converter synthesis is presented. Some examples illustrate this systematic method. Finally, the notions of commutation cell and soft commutation are introduced and discussed.

  20. KML-Based Access and Visualization of High Resolution LiDAR Topography

    Science.gov (United States)

    Crosby, C. J.; Blair, J. L.; Nandigam, V.; Memon, A.; Baru, C.; Arrowsmith, J. R.

    2008-12-01

    Over the past decade, there has been dramatic growth in the acquisition of LiDAR (Light Detection And Ranging) high-resolution topographic data for earth science studies. Capable of providing digital elevation models (DEMs) more than an order of magnitude higher resolution than those currently available, LiDAR data allow earth scientists to study the processes that contribute to landscape evolution at resolutions not previously possible yet essential for their appropriate representation. These datasets also have significant implications for earth science education and outreach because they provide an accurate representation of landforms and geologic hazards. Unfortunately, the massive volume of data produced by LiDAR mapping technology can be a barrier to their use. To make these data available to a larger user community, we have been exploring the use of Keyhole Markup Language (KML) and Google Earth to provide access to LiDAR data products and visualizations. LiDAR digital elevation models are typically delivered in a tiled format that lends itself well to a KML-based distribution system. For LiDAR datasets hosted in the GEON OpenTopography Portal (www.opentopography.org) we have developed KML files that show the extent of available LiDAR DEMs and provide direct access to the data products. Users interact with these KML files to explore the extent of the available data and are able to select DEMs that correspond to their area of interest. Selection of a tile loads a download that the user can then save locally for analysis in their software of choice. The GEON topography system also has tools available that allow users to generate custom DEMs from LiDAR point cloud data. This system is powerful because it enables users to access massive volumes of raw LiDAR data and to produce DEM products that are optimized to their science applications. We have developed a web service that converts the custom DEM models produced by the system to a hillshade that is delivered to

  1. 3D high-resolution thermomechanical modeling of Venus coronae and novae

    Science.gov (United States)

    Gerya, Taras

    2013-04-01

    513 coronae and 64 novae are large (typically several hundred km across) circular surface features on Venus, whose complex structures, with traces of tectonic and magmatic activity as well as their mutual relationship remain enigmatic. Several competing hypotheses were proposed for both coronae and novae based on variability of their sizes, shapes, internal structures and topography, yet little work has been done for quantitative testing of these hypotheses. Here we demonstrate based on new high-resolution three-dimensional thermomechanical numerical model that formation of medium sized (50-300 km) novae and coronae can be explained by tectono-magmatic interaction of mantle plume with hot and thin lithosphere, which has thick low-viscosity lower-middle crust and thin brittle upper crust characterized by elevated surface temperature. According to this model, the process is initiated by decompression melting of hot plume material, which penetrates to the bottom of the lower crust. This melting produces large amount of mafic magma intruding into the ductile lower crust and triggering crustal melting and convection. The crustal convection cell exists for up to several tens of millions years where plume magma and partially molten lower-middle crustal rocks interact and mechanically mix causing gradual thinning and then breaking and fragmentation of the brittle upper crustal lid. The long time span of the convection cell is maintained by the plume heat, which causes gradual warming and melting of crustal rocks. Up to six subsequent stages of the convection cell evolution are found in the experiments : (1) pre-nova stage, (2) young and (3) mature nova stages, and (4) advancing, (5) subsiding and (6) fossil corona stages, which differ in term of crustal structure and fracturing and topography patterns. Novae forms at the initial stage of the process by radial fracturing of the uplifted region above the actively rising convection cell center. At the later stage, such novae

  2. Landscape correlates of forest plant invasions: A high-resolution analysis across the eastern United States

    Science.gov (United States)

    Kurt Riitters; Kevin Potter; Basil V. Iannone; Christopher Oswalt; Songlin Fei; Qinfeng Guo; Tomas Vaclavik

    2017-01-01

    Aim: Invasive species occurrence is often related to the anthropogenic context of a given area. Quantifying the effects of roads is of particular interest as roads are a major vector for invasion. Our objective was to further quantify the effects of roads on forest plant invasion through a macroscale, high-resolution investigation to assist...

  3. High-resolution second-harmonic microscopy of poled silica waveguides

    DEFF Research Database (Denmark)

    Beermann, Jonas; Bozhevolnyi, Sergey I.; Pedersen, Kjeld

    2003-01-01

    A second-harmonic scanning optical microscopy (SHSOM) apparatus operating in reflection is used for high-resolution imaging of second-order optical non-linearities (SONs) in electric-field poled silica-based waveguides. SHSOM of domain walls in a periodically poled KTiOPO_4 crystal is performed...

  4. High-resolution second-harmonic microscopy of poled silica waveguides

    DEFF Research Database (Denmark)

    Beermann, Jonas; Bozhevolnyi, Sergey I.; Pedersen, Kjeld

    2003-01-01

    A second-harmonic scanning optical microscopy (SHSOM) apparatus operating in reflection is used for high-resolution imaging of second-order optical non-linearities (SONs) in electric-field poled silica-based waveguides. SHSOM of domain walls in a periodically poled KTiOPO4 crystal is performed...

  5. New Technique for High Resolution DNA Sizing in Epi-Illumination

    NARCIS (Netherlands)

    Schins, J.M.; Agronskaia, A.; Agronskaia, Alexandra; de Grooth, B.G.; Greve, Jan

    1998-01-01

    We present a high-resolution DNA-sizing technique based on the principles of flow cytometry, using a high numerical aperture objective and epi-illumination. The new technique, designed for small fluorescing samples/particles (sub-micron diameter) suspended in a weakly fluorescent medium, makes use

  6. High resolution optically stimulated luminescence dating of a sediment core from the southwestern Sea of Okhotsk

    DEFF Research Database (Denmark)

    Sugisaki, S.; Buylaert, J. P.; Murray, A. S.

    2012-01-01

    Optically stimulated luminescence (OSL) dating is now widely accepted as a chronometer for terrestrial sediment. More recently, it has been suggested that OSL may also be useful in the dating of deep-sea marine sediments. In this paper, we test the usefulness of high resolution quartz OSL dating ...

  7. High-resolution fractionation after gas chromatography for Effect Directed Analysis.

    NARCIS (Netherlands)

    Pieke, E.; Heus, F.A.H.; Kamstra, J.; Mladic, M.; van Velzen, M.; Kamminga, D.; Lamoree, M.H.; Hamers, T.; Leonards, P.E.G.; Niessen, W.M.A.; Kool, J.

    2013-01-01

    This research presents an analytical technology for highly efficient, high-resolution, and high-yield fractionation of compounds after gas chromatography (GC) separations. The technology is straightforward, does not require sophisticated cold traps or adsorbent traps, and allows collecting large

  8. Spectroscopic Characterisation of CARMENES Target Candidates from FEROS, CAFE and HRS High-Resolution Spectra

    Science.gov (United States)

    Passegger, Vera Maria; Reiners, Ansgar; Jeffers, Sandra V.; Wende, Sebastian; Schöfer, Patrick; Amado, Pedro J.; Caballero, Jose A.; Montes, David; Mundt, Reinhard; Ribas, Ignasi; Quirrenbach, Andreas

    2016-07-01

    CARMENES (Calar Alto high-Resolution search for M dwarfs with Exoearths with Near-infrared and optical Échelle Spectrographs) started a new planet survey on M-dwarfs in January this year. The new high-resolution spectrographs are operating in the visible and near-infrared at Calar Alto Observatory. They will perform high-accuracy radial-velocity measurements (goal 1 m s-1) of about 300 M-dwarfs with the aim to detect low-mass planets within habitable zones. We characterised the candidate sample for CARMENES and provide fundamental parameters for these stars in order to constrain planetary properties and understand star-planet systems. Using state-of-the-art model atmospheres (PHOENIX-ACES) and χ2-minimization with a downhill-simplex method we determine effective temperature, surface gravity and metallicity [Fe/H] for high-resolution spectra of around 480 stars of spectral types M0.0-6.5V taken with FEROS, CAFE and HRS. We find good agreement between the models and our observed high-resolution spectra. We show the performance of the algorithm, as well as results, parameter and spectral type distributions for the CARMENES candidate sample, which is used to define the CARMENES target sample. We also present first preliminary results obtained from CARMENES spectra.

  9. Effects of angling and manual handling on pike behaviour investigated by high-resolution positional telemetry

    DEFF Research Database (Denmark)

    Baktoft, Henrik; Aarestrup, Kim; Berg, Søren

    2013-01-01

    Human disturbances such as angling and manual handling may have long-term effects on the behaviour of pike, Esox lucius L., an ecologically important species. Using continuous high-resolution positional telemetry, this study compared the swimming activity of handled and unhandled pike in a small...

  10. Pd grating obtained by direct micromolding for use in high resolution ...

    Indian Academy of Sciences (India)

    the pattern when used as an optical grating produced a diffraction pattern with a high resolution (>2000); the inten- sities of widely separated ... Keywords. Micromolding technique; Pd grating; Cu electroless deposition; diffraction efficiency; optical diffraction. 1. .... ethanol to remove any uncured polymer. The resulting stamp.

  11. Decoding Overlapping Memories in the Medial Temporal Lobes Using High-Resolution fMRI

    Science.gov (United States)

    Chadwick, Martin J.; Hassabis, Demis; Maguire, Eleanor A.

    2011-01-01

    The hippocampus is proposed to process overlapping episodes as discrete memory traces, although direct evidence for this in human episodic memory is scarce. Using green-screen technology we created four highly overlapping movies of everyday events. Participants were scanned using high-resolution fMRI while recalling the movies. Multivariate…

  12. Resolution enhancement of low quality videos using a high-resolution frame

    NARCIS (Netherlands)

    Pham, T.Q.; Van Vliet, L.J.; Schutte, K.

    2006-01-01

    This paper proposes an example-based Super-Resolution (SR) algorithm of compressed videos in the Discrete Cosine Transform (DCT) domain. Input to the system is a Low-Resolution (LR) compressed video together with a High-Resolution (HR) still image of similar content. Using a training set of

  13. The AX-PET project Demonstration of a high resolution axial 3D PET

    CERN Document Server

    Bolle, E; Casella, C; Chesi, E; Clinthorne, N; Cochran, E; De Leo, R; Dissertori, G; Djambazov, G; Fanti, V; Honscheid, K; Huh, S; Johnson, I; Joram, C; Kagan, H; Lustermann, W; Meddi, F; Nappi, E; Nessi-Tedaldi, F; Oliver, J F; Pauss, P; Rafecas, M; Renker, D; Rudge, A; Schinzel, D; Schneider, T; Seguinot, J; Smith, S; Solevi, P; Stapnes, S; Weilhammer, P

    2010-01-01

    The AX-PET is a new geometrical concept for a high resolution 3D PET scanner, based on matrices of axially oriented LYSO crystals interleaved by stacks of WLS, both individually read out by G-APDs. A PET demonstrator, based on two detector modules used in coincidence, is currently under construction.

  14. High Resolution FTIR Spectroscopy of Trisulfane Hsssh: a Candidate for Detecting Parity Violation in Chiral Molecules

    Science.gov (United States)

    Albert, Sieghard; Bolotova, Irina; Chen, Ziqiu; Fábri, Csaba; Quack, Martin; Seyfang, Georg; Zindel, Daniel

    2017-06-01

    The measurement of the parity violating energy difference Δ_{pv}{E} between the enantiomers of chiral molecules is among the major current challenges in high resolution spectroscopy and physical-chemical stereochemistry. Theoretical predictions have recently identified dithiine^{b} and trisulfane as suitable candidates for such experiments. We report the first successful high-resolution analyses of the Fourier transform infrared (FTIR) spectra of trisulfane. A band centered at 861.0292 cm^{-1} can be assigned unambiguously to the chiral trans conformer by means of ground state combination differences in comparison with known pure rotational spectra. A second band near 864.698 cm^{-1} is tentatively assigned to the cis conformer by comparison with theory. M. Quack , Fundamental Symmetries and Symmetry Violations from High-resolution Spectroscopy, Handbook of High Resolution Spectroscopy, M. Quack and F. Merkt eds.,John Wiley & Sons Ltd, Chichester, New York, 2001, vol. 1, ch. 18, pp. 659-722. S. Albert, I. Bolotova, Z. Chen, C. Fábri, L. Horný, M. Quack, G. Seyfang and D. Zindel, Phys.Chem.Chem.Phys.18, 21976-21993 (2016). C. Fábri, L. Horný and M. Quack, ChemPhysChem16, 3584-3589 (2015). M. Liedtke, K. M. T. Yamada, G. Winnewisser and J. Hahn, J.Mol.Struct.413, 265-270 (1997).

  15. Ultra-high aspect ratio high-resolution nanofabrication for hard X-ray diffractive optics

    Science.gov (United States)

    Chang, Chieh; Sakdinawat, Anne

    2014-06-01

    Although diffractive optics have played a major role in nanoscale soft X-ray imaging, high-resolution and high-efficiency diffractive optics have largely been unavailable for hard X-rays where many scientific, technological and biomedical applications exist. This is owing to the long-standing challenge of fabricating ultra-high aspect ratio high-resolution dense nanostructures. Here we report significant progress in ultra-high aspect ratio nanofabrication of high-resolution, dense silicon nanostructures using vertical directionality controlled metal-assisted chemical etching. The resulting structures have very smooth sidewalls and can be used to pattern arbitrary features, not limited to linear or circular. We focus on the application of X-ray zone plate fabrication for high-efficiency, high-resolution diffractive optics, and demonstrate the process with linear, circular, and spiral zone plates. X-ray measurements demonstrate high efficiency in the critical outer layers. This method has broad applications including patterning for thermoelectric materials, battery anodes and sensors among others.

  16. High resolution 3D seismic survey off-shore the Netherlands

    NARCIS (Netherlands)

    Steeghs, P.; Vandeweijer, V.P.; Meekes, J.A.C.; Paap, B.F.; Kleine, M.P.E. de

    2014-01-01

    TNO has carried out a high resolution 3D seismic survey off-shore Rotterdam. The new deployment concept that was tested with this survey results in high-quality 3D images of the shallow subsurface at relatively low cost, particularly in comparison with conventional 3D seismic data acquisition.

  17. A dynamic aerodynamic resistance approach to calculate high resolution sensible heat fluxes in urban areas

    Science.gov (United States)

    Crawford, Ben; Grimmond, Sue; Kent, Christoph; Gabey, Andrew; Ward, Helen; Sun, Ting; Morrison, William

    2017-04-01

    Remotely sensed data from satellites have potential to enable high-resolution, automated calculation of urban surface energy balance terms and inform decisions about urban adaptations to environmental change. However, aerodynamic resistance methods to estimate sensible heat flux (QH) in cities using satellite-derived observations of surface temperature are difficult in part due to spatial and temporal variability of the thermal aerodynamic resistance term (rah). In this work, we extend an empirical function to estimate rah using observational data from several cities with a broad range of surface vegetation land cover properties. We then use this function to calculate spatially and temporally variable rah in London based on high-resolution (100 m) land cover datasets and in situ meteorological observations. In order to calculate high-resolution QH based on satellite-observed land surface temperatures, we also develop and employ novel methods to i) apply source area-weighted averaging of surface and meteorological variables across the study spatial domain, ii) calculate spatially variable, high-resolution meteorological variables (wind speed, friction velocity, and Obukhov length), iii) incorporate spatially interpolated urban air temperatures from a distributed sensor network, and iv) apply a modified Monte Carlo approach to assess uncertainties with our results, methods, and input variables. Modeled QH using the aerodynamic resistance method is then compared to in situ observations in central London from a unique network of scintillometers and eddy-covariance measurements.

  18. Development of a High Resolution Airborne Millimeter Wave FM-CW SAR

    NARCIS (Netherlands)

    Meta, A.; Wit, J.J.M. de; Hoogeboom, P.

    2004-01-01

    The combination of compact FM-CW radar technology and high resolution SAR processing techniques should pave the way for the development of a small, lightweight and cost effective imaging radar. In the field of airborne earth observation, SAR is however a novel application for FM-CW radars. At IRCTR

  19. Refinement procedure for the image alignment in high-resolution electron tomography

    Energy Technology Data Exchange (ETDEWEB)

    Houben, L., E-mail: l.houben@fz-juelich.de [Peter Gruenberg Institute and Ernst Ruska-Centre for Microscopy and Spectroscopy with Electrons (ER-C), Research Centre Juelich, 52425 Juelich (Germany); Bar Sadan, M. [Peter Gruenberg Institute and Ernst Ruska-Centre for Microscopy and Spectroscopy with Electrons (ER-C), Research Centre Juelich, 52425 Juelich (Germany)

    2011-08-15

    High-resolution electron tomography from a tilt series of transmission electron microscopy images requires an accurate image alignment procedure in order to maximise the resolution of the tomogram. This is the case in particular for ultra-high resolution where even very small misalignments between individual images can dramatically reduce the fidelity of the resultant reconstruction. A tomographic-reconstruction based and marker-free method is proposed, which uses an iterative optimisation of the tomogram resolution. The method utilises a search algorithm that maximises the contrast in tomogram sub-volumes. Unlike conventional cross-correlation analysis it provides the required correlation over a large tilt angle separation and guarantees a consistent alignment of images for the full range of object tilt angles. An assessment based on experimental reconstructions shows that the marker-free procedure is competitive to the reference of marker-based procedures at lower resolution and yields sub-pixel accuracy even for simulated high-resolution data. -- Highlights: {yields} Alignment procedure for electron tomography based on iterative tomogram contrast optimisation. {yields} Marker-free, independent of object, little user interaction. {yields} Accuracy competitive with fiducial marker methods and suited for high-resolution tomography.

  20. High resolution Holocene paleomagnetic secular variation records from Bay of Bengal

    Digital Repository Service at National Institute of Oceanography (India)

    Usapkar, A.; Dewangan, P.; Badesab, F.K.; Mazumdar, A.; Ramprasad, T.; Krishna, K.S.; Basavaiah, N.

    We present high resolution paleosecular variation (PSV) records up to 8 cal. kyr BP from three piston cores, MD161/8, MD161/11 and MD161/13 acquired in the Krishna-Godavari (KG) basin, Bay of Bengal. During the Holocene period, high sedimentation...