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Sample records for high-resolution computerized tomography

  1. Diagnostic Yield of Transbronchial Biopsy in Comparison to High Resolution Computerized Tomography in Sarcoidosis Cases

    Science.gov (United States)

    Akten, H Serpil; Kilic, Hatice; Celik, Bulent; Erbas, Gonca; Isikdogan, Zeynep; Turktas, Haluk; Kokturk, Nurdan

    2018-04-25

    This study aimed to evaluate the diagnostic yield of fiberoptic bronchoscopic (FOB) transbronchial biopsy and its relation with quantitative findings of high resolution computerized tomography (HRCT). A total of 83 patients, 19 males and 64 females with a mean age of 45.1 years diagnosed with sarcoidosis with complete records of high resolution computerized tomography were retrospectively recruited during the time period from Feb 2005 to Jan 2015. High resolution computerized tomography scans were retrospectively assessed in random order by an experienced observer without knowledge of the bronchoscopic results or lung function tests. According to the radiological staging with HRCT, 2.4% of the patients (n=2) were stage 0, 19.3% (n=16) were stage 1, 72.3% (n=60) were stage 2 and 6.0% (n=5) were stage 3. This study showed that transbronchial lung biopsy showed positive results in 39.7% of the stage I or II sarcoidosis patients who were diagnosed by bronchoscopy. Different high resolution computerized tomography patterns and different scores of involvement did make a difference in the diagnostic accuracy of transbronchial biopsy (p=0.007). Creative Commons Attribution License

  2. 'High resolution' computerized tomography in spinal narrow and spinal column diagnosis

    International Nuclear Information System (INIS)

    Koester, O.

    1985-01-01

    Bearing in mind that direct comparison is lacking, high resolution computerized tomography in spinal column diagnosis can be said to supply considerably increased information when dealing with the issues of a cervical prolapse and bony changes of any origin. Its advantages appear to be reduced when assessing lumbar prolapse, intraspinal masses and paravertebral soft-tissue processes. (orig.) [de

  3. Highly resolving computerized tomography

    International Nuclear Information System (INIS)

    Kurtz, B.; Petersen, D.; Walter, E.

    1984-01-01

    With the development of highly-resolving devices for computerized tomography, CT diagnosis of the lumbar vertebral column has gained increasing importance. As an ambulatory, non-invasive method it has proved in comparative studies to be at least equivalent to myelography in the detection of dislocations of inter-vertebral disks (4,6,7,15). Because with modern devices not alone the bones, but especially the spinal soft part structures are clearly and precisely presented with a resolution of distinctly below 1 mm, a further improvement of the results is expected as experience will increase. The authors report on the diagnosis of the lumbar vertebral column with the aid of a modern device for computerized tomography and wish to draw particular attention to the possibility of doing this investigation as a routine, and to the diagnostic value of secondary reconstructions. (BWU) [de

  4. Highly resolving computerized tomography

    Energy Technology Data Exchange (ETDEWEB)

    Kurtz, B.; Petersen, D.; Walter, E.

    1984-01-01

    With the development of highly-resolving devices for computerized tomography, CT diagnosis of the lumbar vertebral column has gained increasing importance. As an ambulatory, non-invasive method it has proved in comparative studies to be at least equivalent to myelography in the detection of dislocations of inter-vertebral disks (4,6,7,15). Because with modern devices not alone the bones, but especially the spinal soft part structures are clearly and precisely presented with a resolution of distinctly below 1 mm, a further improvement of the results is expected as experience will increase. The authors report on the diagnosis of the lumbar vertebral column with the aid of a modern device for computerized tomography and wish to draw particular attention to the possibility of doing this investigation as a routine, and to the diagnostic value of secondary reconstructions.

  5. Computerized tomography using high resolution X-ray imaging system with a microfocus source

    International Nuclear Information System (INIS)

    Zaprazny, Z.; Korytar, D.; Konopka, P.; Ac, V.; Bielecki, J.

    2011-01-01

    In recent years there is an effort to image an internal structure of an object by using not only conventional 2D X-ray radiography but also using high resolution 3D tomography which is based on reconstruction of multiple 2D projections at various angular positions of the object. We have previously reported [1] the development and basic parameters of a high resolution x-ray imaging system with a microfocus source. We report the recent progress using this high resolution X-ray laboratory system in this work. These first findings show that our system is particularly suitable for light weight and nonmetallic objects such as biological objects, plastics, wood, paper, etc. where phase contrast helps to increase the visibility of the finest structures of the object. Phase-contrast X-ray Computerized Tomography is of our special interest because it is an emerging imaging technique that can be implemented at third generation synchrotron radiation sources and also in laboratory conditions using a microfocus X-ray tube or beam conditioning optics. (authors)

  6. Interstitial lung illness: Discoveries in x-ray of the thorax vs computerized tomography of high resolution

    International Nuclear Information System (INIS)

    Patino O, Maria Olga; Gomez Ramirez, Rafael

    1993-01-01

    This study wants to prove the advantages of the computerized axial tomography (TAC) of high resolution on the conventional radiography and the follow-up of the patients with interstitial pulmonary disease (IPD). 29 patients were studied with conventional RX and TAC with 17. $ % of high resolution which had normal radiography with clear abnormalities in the TAC of high resolution, the type of interstitial pulmonary disease (IPD). In the 68,9% of the cases it showed abnormality as well in TAC as in conventional RX. In the fact, that the TAC does not allow a specific etiologic diagnosis of the IPD type, as it is done in the biopsy. It allows identifying abnormality in those patients apparently normal by the radiography of the thorax and when it already exists the histopathologic diagnosis it allows the follow-up in a no invasive way

  7. Computerized tomography

    International Nuclear Information System (INIS)

    Rubashov, I.B.

    1985-01-01

    Operating principle is described for the devices of computerized tomography used in medicine for diagnosis of brain diseases. Computerized tomography is considered as a part of computerized diagnosis, as a part of information science. It is shown that computerized tomography is a real existed field of investigations in medicine and industrial production

  8. Diffuse lung neoplasms. Correlation between high resolution computerized tomography and anatomopathology; Neoplasias pulmonares difusas: correlacao da tomografia computadorizada de alta resolucao com a anatomopatologia

    Energy Technology Data Exchange (ETDEWEB)

    Marchiori, Edson [Universidade Federal Fluminense, Niteroi, RJ (Brazil). Dept. de Radiologia; Irion, Klaus L. [Complexo Hospitalar Santa Casa de Porto Alegre, RS (Brazil). Servico de Radiologia do Pavilhao Pereira Filho; Souza Junior, Arthur Soares [Faculdade de Medicina de Sao Jose do Rio Preto, SP (Brazil)]. E-mail: edmarchiori@zipmail.com.br

    2002-08-01

    A short comparative evaluation study between high resolution computerized tomography and anatomopathologic findings is presented. The association of these two diagnostic techniques is discussed as a factor to enhance the accuracy of diffuse lung diseases, such as carcinomatous lymphangitis, Kaposi's Sarcoma, lymphomas, hematogenic metastases, bronchiole-alveolar carcinoma and leukemia. (MAC)

  9. Role of computerized tomography in diagnosis of atypical gall bladder and common bile duct stones

    International Nuclear Information System (INIS)

    El-Husseni, Tareq K.; Al-Shebrein, Ibrahim A.

    2001-01-01

    Objective was to assess the value of computerized tomography as an adjuvant to ultrasound in the diagnosis of atypical gallbladder and common duct stone disease. Real time ultrasound scanning for the gallbladder and common duct was performed in the routine manner. High resolution computerized tomography images were subsequently obtained for the region of interest. Computerized tomography resolved undetermined results as follows: 1. Non shadowing gallbladder debris (6 points), 2. Focal gallbladder wall thickening (2 points), 3. Stone obscured by calcified gallbladder wall (3 points), 4. Non visualized gallbladder double arc shadow (4 points), 5 and 6. Impacted gallbladder neck and common duct stones (18 points), computerized tomography gave false positive diagnosis in (2 points). Computerized tomography provided an effective and reliable means for the diagnosis of atypical gallbladder calculi when ultrasound was imprecise or the findings contradicted the clinical presentation. Finally if gallbladder neck or common duct stones are suspected, in addition to computerized tomography other imaging techniques such as magnetic resonance cholangio pancreatography or endoscopic retrograde cholangiopancreatography in addition to computerized tomography may be needed to avoid false positive diagnosis prior to surgery. (author)

  10. Single-Photon Emission Computerized Tomography (SPECT in Neuropsychiatry: A Review

    Directory of Open Access Journals (Sweden)

    B. K. Puri

    1992-01-01

    Full Text Available Cranial single-photon emission computerized tomography (SPECT or SPET can now give regional cerebral blood flow images with a resolution approaching that of positron emission tomography (PET. In this paper, the use of high resolution SPECT neuroimaging in neuropsychiatric disorders, including Alzheimer's disease, multi-infarct dementia, Pick's disease, progressive supranuclear palsy, Korsakoff's psychosis, Creutzfeld-Jakob disease, Parkinson's disease, Huntington's disease, schizophrenia, mood disorders, obsessive–compulsive disorder, HIV infection and AIDS is reviewed. Finally, further potential research and clinical uses, based on ligand studies, are outlined.

  11. Single photon emission computerized tomography (SPECT)

    International Nuclear Information System (INIS)

    Ganatra, R.D.

    1992-01-01

    Tomography in nuclear medicine did not originate after the introduction of X-ray computerized tomography (CT). Even in the days of rectilinear scanner, tomography was attempted with multiple detector heads rotating around the patient, but the counts at each plane were never very high to obtain a satisfactory image. A high resolution focusing collimator can look at different depths but taking several slices in one projection was a time consuming process. Rectilinear scanners lose lot of counts in the collimator to look at one point, at on time, in one plane. It is true that attempts to do tomography with gamma camera really got a boost after the success of CT. By that time, algorithms for doing reconstruction of images also were highly refined and for advanced. Clinical application of SPECT has become widespread now, because of the development of suitable radiopharmaceuticals and improvement in instrumentation. The SPECT provides a direct measure of regional organ function and is performed with nuclides such as 123 I and 99 Tc m that emit a mono-image photon during their decay. SPECT is far less expensive than positron emission tomography

  12. Single photon emission computerized tomography (SPECT)

    Energy Technology Data Exchange (ETDEWEB)

    Ganatra, R D

    1993-12-31

    Tomography in nuclear medicine did not originate after the introduction of X-ray computerized tomography (CT). Even in the days of rectilinear scanner, tomography was attempted with multiple detector heads rotating around the patient, but the counts at each plane were never very high to obtain a satisfactory image. A high resolution focusing collimator can look at different depths but taking several slices in one projection was a time consuming process. Rectilinear scanners lose lot of counts in the collimator to look at one point, at on time, in one plane. It is true that attempts to do tomography with gamma camera really got a boost after the success of CT. By that time, algorithms for doing reconstruction of images also were highly refined and for advanced. Clinical application of SPECT has become widespread now, because of the development of suitable radiopharmaceuticals and improvement in instrumentation. The SPECT provides a direct measure of regional organ function and is performed with nuclides such as {sup 123}I and {sup 99}Tc{sup m} that emit a mono-image photon during their decay. SPECT is far less expensive than positron emission tomography

  13. Measurement on the density resolution of industrial computerized tomography by using disc specimen with holes

    International Nuclear Information System (INIS)

    Tian, Y.; Gao, D.; Zhang, W.; Xia, Z.; Yang, C.

    2004-01-01

    Several ways mainly used for measuring the density resolution of industrial computerized tomography (ICT) are briefly introduced. Based on the equivalent conversion between volume variation and density variation, a kind of disc specimen with holes is designed to measure the density resolution of ICT. In this experiment, a kind of high quality polymethyl methacylate (PMMA) is selected to make specimens with diameter of 250mm, in which six sets of holes with diameter separately 0.5mm, 1.0mm, 1.5mm, 2.0mm, 2.5mm, and 3.0mm are distributed in the radial directions with interval of 60 o between two neighboring sets, and in the same set, the distances of holes departing the center of the specimen are respectively 20mm, 40mm, 60mm, 80mm, and 100mm. The experiment shows that the method is sensitive, simple, flexible, and practical. About 0.2% density resolution of region of interest (ROI) with diameter 20mm can be verified, the relationship between CT value of ROI and its position can be obtained, and at the same time the spatial resolution of ICT can be measured in high quality. (author)

  14. Anti-3-[(18)F]FACBC positron emission tomography-computerized tomography and (111)In-capromab pendetide single photon emission computerized tomography-computerized tomography for recurrent prostate carcinoma: results of a prospective clinical trial.

    Science.gov (United States)

    Schuster, David M; Nieh, Peter T; Jani, Ashesh B; Amzat, Rianot; Bowman, F Dubois; Halkar, Raghuveer K; Master, Viraj A; Nye, Jonathon A; Odewole, Oluwaseun A; Osunkoya, Adeboye O; Savir-Baruch, Bital; Alaei-Taleghani, Pooneh; Goodman, Mark M

    2014-05-01

    We prospectively evaluated the amino acid analogue positron emission tomography radiotracer anti-3-[(18)F]FACBC compared to ProstaScint® ((111)In-capromab pendetide) single photon emission computerized tomography-computerized tomography to detect recurrent prostate carcinoma. A total of 93 patients met study inclusion criteria who underwent anti-3-[(18)F]FACBC positron emission tomography-computerized tomography plus (111)In-capromab pendetide single photon emission computerized tomography-computerized tomography for suspected recurrent prostate carcinoma within 90 days. Reference standards were applied by a multidisciplinary board. We calculated diagnostic performance for detecting disease. In the 91 of 93 patients with sufficient data for a consensus on the presence or absence of prostate/bed disease anti-3-[(18)F]FACBC had 90.2% sensitivity, 40.0% specificity, 73.6% accuracy, 75.3% positive predictive value and 66.7% negative predictive value compared to (111)In-capromab pendetide with 67.2%, 56.7%, 63.7%, 75.9% and 45.9%, respectively. In the 70 of 93 patients with a consensus on the presence or absence of extraprostatic disease anti-3-[(18)F]FACBC had 55.0% sensitivity, 96.7% specificity, 72.9% accuracy, 95.7% positive predictive value and 61.7% negative predictive value compared to (111)In-capromab pendetide with 10.0%, 86.7%, 42.9%, 50.0% and 41.9%, respectively. Of 77 index lesions used to prove positivity histological proof was obtained in 74 (96.1%). Anti-3-[(18)F]FACBC identified 14 more positive prostate bed recurrences (55 vs 41) and 18 more patients with extraprostatic involvement (22 vs 4). Anti-3-[(18)F]FACBC positron emission tomography-computerized tomography correctly up-staged 18 of 70 cases (25.7%) in which there was a consensus on the presence or absence of extraprostatic involvement. Better diagnostic performance was noted for anti-3-[(18)F]FACBC positron emission tomography-computerized tomography than for (111)In-capromab pendetide single

  15. Bronchial asthma: correlation of high resolution computerized tomography findings with clinical data

    International Nuclear Information System (INIS)

    Mogami, Roberto; Marchiori, Edson; Kirk, Kennedy; Capone, Domenico; Daltro, Pedro

    1999-01-01

    In this work we did a sectional study of 31 asthmatic patients with several levels of disease severity, which were submitted to high resolution computed tomography of the thorax and spirometry, between the months of July, 1995 and August, 1997. The tomographic findings were correlated with the clinical classification of the patients and the most frequent tomographic findings were bronchial wall thickening, bronchial dilatation, air trapping, centrilobular opacities, cicatricial linear shadows, mucoid impaction, emphysema and atelectasis. In asthmatic patients of long duration we observed small airway disease and irreversible lesions as the predominant findings. In smoking patients there was no high frequency of emphysema. (author)

  16. Computerized tomography in the diagnosis of hyperparathyroidism

    International Nuclear Information System (INIS)

    Sobota, J.; Girl, J.; Sotornik, I.; Kocandrle, V.

    1990-01-01

    Long-term experience in the application of computerized tomography to the diagnosis of hyperparathyroidism is summarized. Based on a large number of examinations (164) of parathyroid glands associated with the possibility of verification and comparison with the results of ultrasonography and other imaging methods, the potential of computerized tomography in the diagnosis of hyperparathyroidism and its advantages and limitations are summarized. It is concluded that owing to its high diagnostic precision, this technique can be regarded reliable in detecting enlarged parathyroid glands. (author). 11 figs., 1 tab., 19 refs

  17. Evaluation of brain scintigraphy and computerized tomography

    International Nuclear Information System (INIS)

    Cavailloles, F.; Dairou, R.; Desbleds, M.T.; Benoit, C.; Larmande, P.; Bok, B.; Alperovitch, A.

    1983-01-01

    In order to assess the clinical usefulness of brain computerized tomography and radionuclide scan, a prospective study was performed on a series of 554 patients. The detection rate was assessed as well as the identification rate of lesions. In addition, the usefulness of both tests was appreciated subjectively by two neurologists reviewing the patients' files. Both give reasonably similar results: computerized tomography is superior to radionuclide scan in the diagnosis of tumors and intracerebral hematomas, the radionuclide scan being slightly superior in the diagnosis of purely ischemic CVA and subdural hematomas. The superiority which was subjectively conceded to computerized tomography was greater than that objectively demonstrated. However, clinical usefulness of computerized tomography was judged important in only 50% of the cases. Moreover, to request both computerized tomography and radionuclide scan appeared as having no interest in 83% of the cases. In that series, the diagnostic hypotheses were in agreement with the final diagnosis in 88% of the cases. Bias encountered in this type of studies are discussed [fr

  18. Computerized tomography in myotonic dystrophy

    International Nuclear Information System (INIS)

    Gellerich, I.; Mueller, D.; Koch, R.D.

    1986-01-01

    Besides clinical symptoms, progress and electromyography computerized tomography improves the diagnostics of myotonic dystrophy. Even small changes in muscular structure are detectable and especially the musculus soleus exhibits early and pronounced alterations. By means of density distribution pattern an improved characterization of the disease is possible. Additional information is obtained by cerebral computerized tomography. Atrophy of brain tissue is to be expected in all patients with myotonic dystrophy. (author)

  19. Computerized tomography used in non-destructive testing of welded pipes

    Energy Technology Data Exchange (ETDEWEB)

    Iovea, M; Rizescu, C; Georgescu, G; Marinescu, A; Chitescu, P; Sava, T; Neagu, M; Avram, D [Institute of Research and Design for Electrical Engineering, ICPE - Electrostatica Splaiul Unirii 313, Sect. 3, R-74204 Bucharest (Romania)

    1997-12-31

    High quality standards in operation of National Power System is ensured by the use of high performance techniques and systems for Non-Destructive Testing (NDT). In recent years a number of new developments of the non-conventional technologies in the field of NDT have been achieved. In our laboratory there have been developed two computerized technologies using {gamma}-ray computed tomography and ultrasonic imaging methods. The standard techniques for imaging from projection data is computerized tomography. The industrial computerized tomography methods consist in the measurement of thin X - or {gamma}-ray beam attenuation when passing through some selected surface of the tested object, along several directions, so that by means of an adequate mathematical algorithm, a map of linear attenuation coefficients for the scanned surface is obtained. In fact, this map gives the density of materials occurring in the surface plane. Computerized tomography equipment, in various constructive versions, are intended for the following applications: (1) NDT in those fields requiring strict control of product quality, as for instance the nuclear energy, military industry, aeronautics, transportation fields, etc., (2) research in field of materials technology, machine engineering, metallurgy, welding, etc. This paper presents the applications of Computerized Tomography in NDT, by showing the results obtained on welded pipes, as well as the facilities offered by this method. In the final part, the paper presents the concept of a mobile tomography system for industrial pipes testing. (author). 2 figs., 7 refs.

  20. Computerized tomography used in non-destructive testing of welded pipes

    International Nuclear Information System (INIS)

    Iovea, M.; Rizescu, C.; Georgescu, G.; Marinescu, A.; Chitescu, P.; Sava, T.; Neagu, M.; Avram, D.

    1996-01-01

    High quality standards in operation of National Power System is ensured by the use of high performance techniques and systems for Non-Destructive Testing (NDT). In recent years a number of new developments of the non-conventional technologies in the field of NDT have been achieved. In our laboratory there have been developed two computerized technologies using γ-ray computed tomography and ultrasonic imaging methods. The standard techniques for imaging from projection data is computerized tomography. The industrial computerized tomography methods consist in the measurement of thin X - or γ-ray beam attenuation when passing through some selected surface of the tested object, along several directions, so that by means of an adequate mathematical algorithm, a map of linear attenuation coefficients for the scanned surface is obtained. In fact, this map gives the density of materials occurring in the surface plane. Computerized tomography equipment, in various constructive versions, are intended for the following applications: 1) NDT in those fields requiring strict control of product quality, as for instance the nuclear energy, military industry, aeronautics, transportation fields, etc., 2) research in field of materials technology, machine engineering, metallurgy, welding, etc. This paper presents the applications of Computerized Tomography in NDT, by showing the results obtained on welded pipes, as well as the facilities offered by this method. In the final part, the paper presents the concept of a mobile tomography system for industrial pipes testing. (author). 2 figs., 7 refs

  1. Computerized axial tomography in traumatic cervical lesions

    International Nuclear Information System (INIS)

    Koyama, Tsunemaro

    1982-01-01

    Although plain computerized axial tomography cannot routinely demonstrate the spinal cord, it does provide excellent visualization of the bony outline of the spinal canal and vertebral column. So it should be reasonable to use this technique in cases of cervical traumatic disorders. In this paper we presented 10 cases of cervical traumatic lesions; 3 atlanto-axial dislocation, 2 cervical canal stenosis, 3 OPLL, 1 intramedullary hematoma and 1 C 2 -neurinoma. In some patients neurologic deficits were induced by cervical trauma. Bony lesions appeared more adequately deliniated than intraspinal lesions, however, in some cases intramedullary changes could also be demonstrated. The use of metrizamide with high resolution CT-scanner could improve the usefullness of this technique. (author)

  2. Ground-glass opacity: High-resolution computed tomography and 64-multi-slice computed tomography findings comparison

    International Nuclear Information System (INIS)

    Sergiacomi, Gianluigi; Ciccio, Carmelo; Boi, Luca; Velari, Luca; Crusco, Sonia; Orlacchio, Antonio; Simonetti, Giovanni

    2010-01-01

    Objective: Comparative evaluation of ground-glass opacity using conventional high-resolution computed tomography technique and volumetric computed tomography by 64-row multi-slice scanner, verifying advantage of volumetric acquisition and post-processing technique allowed by 64-row CT scanner. Methods: Thirty-four patients, in which was assessed ground-glass opacity pattern by previous high-resolution computed tomography during a clinical-radiological follow-up for their lung disease, were studied by means of 64-row multi-slice computed tomography. Comparative evaluation of image quality was done by both CT modalities. Results: It was reported good inter-observer agreement (k value 0.78-0.90) in detection of ground-glass opacity with high-resolution computed tomography technique and volumetric Computed Tomography acquisition with moderate increasing of intra-observer agreement (k value 0.46) using volumetric computed tomography than high-resolution computed tomography. Conclusions: In our experience, volumetric computed tomography with 64-row scanner shows good accuracy in detection of ground-glass opacity, providing a better spatial and temporal resolution and advanced post-processing technique than high-resolution computed tomography.

  3. Algorithmic fundamentals of computerized tomography and of transverse analogue tomography

    International Nuclear Information System (INIS)

    Heckmann, K.

    1981-01-01

    Computerized tomography and transverse analogue tomography are two different approaches to the same goal, namely, transverse tomography. The algorithm is discussed and compared. Transverse tomography appears capable of further development, judging by this comparison. (orig.) [de

  4. Computerized tomography in orthopaedics and traumatology

    International Nuclear Information System (INIS)

    Boettger, E.; Heckl, R.; Rehabilitations-Krankenhaus Langensteinbach, Karlsbad

    1981-01-01

    Computerized tomography in traumatology is the selected method for the indications mentioned, so that angiographic investigations are only necessary in exceptional cases. Computerized tomography is also better than other methods when diagnozing soft part tumours, however, angiography is still indicated preoperatively for individual cases. CT is only good as additional help to conventional diagnostics with bone tumours. The differential diagnosis cysts-tumour is possible using contrast medium injections. The frequently large soft part share of tumours is recognizable with osteolytic tumours so that a better irradiation and operation planning can be effected. Diseases in the spinal canal can only be assessed with reservation using modern equipment. Lumbar dislocations of the disk can mostly not be sufficiently determined. Perivertebral abscesses can be certainly detected using computerized tomography. This is particularly so for abscesses prior to calcification. (orig.) [de

  5. Physical fundamentals of high-resolution computerized tomography

    International Nuclear Information System (INIS)

    Kalender, W.A.; Suess, C.

    1985-01-01

    A model is demonstrated allowing on assessment of the influence of various factors on local or spatial resolution. Separate establishment of data collection, picture reconstruction and representation is important. Different aspects depending on device type obtain when collecting data. When assessing and developing device types further, attention should be given to the weakest chain links which determine local resolution. However, we should never forget that local resolution is but one parameter for describing picture quality. Resolution of low contrasts and freedom from artifacts are at least as important parameters for the assessment of the total CT system. (orig.) [de

  6. Radiographic analysis of body composition by computerized axial tomography

    International Nuclear Information System (INIS)

    Heymsfield, S.B.

    1986-01-01

    Radiographic methods of evaluating body composition have been applied for over five decades. A marked improvement in this approach occurred in the mid-nineteen-seventies with the introduction of computerized axial tomography. High image contrast, cross-sectional imaging and rapid computerized data processing make this technique a sophisticated clinically applicable tool. (author)

  7. Cranial computerized tomography in children suffering from acute leukemia

    International Nuclear Information System (INIS)

    Metz, O.

    1981-01-01

    Cranial computerized (axial) tomography permits a more complete neurologic supervision of children with acute leukemia and a better knowledge of the frequency and varieties of cerebral complications in leukemia. Endocranial complications in acute leukemia are essentially infiltrative, hemorrhagic, infectious or iatrogenic. Cranial computerized tomography can demonstrate cerebral changes in meningeal leukemia, hemorrhages, calcifications, brain atrophy or leukencephalopathy. The preliminary results of cranial computerized tomography in childhood leukemia suggest that the iatrogenic main lesion of the brain due to combined radiation-chemotherapy is atrophy whereas that of the intrathecal cytostatic therapy is demyelination. Accurate diagnostics and control of possible cerebral complications in therapy of leukemia is essentially for appropriate therapeutic management. For that cranial computerized tomography is the best method to a effective supervision of the brain. (author)

  8. High resolution CT in obstructive and air-ways lung disease

    Energy Technology Data Exchange (ETDEWEB)

    Webb, W R [California Univ., San Francisco, CA (United States). Dept. of Radiology

    1996-12-31

    The topics briefly discussed i.e. emphysema, its diagnosis, bronchiectasis etc. HRTC (high resolution computerized tomography) in diagnosing both disease and small airways abnormalities also discussed. (33 refs.).

  9. High resolution CT in obstructive and air-ways lung disease

    International Nuclear Information System (INIS)

    Webb, W.R.

    1995-01-01

    The topics briefly discussed i.e. emphysema, its diagnosis, bronchiectasis etc. HRTC (high resolution computerized tomography) in diagnosing both disease and small airways abnormalities also discussed. (33 refs.)

  10. Computerized tomography in evaluation of the pulmonary hilum

    International Nuclear Information System (INIS)

    Secaf, M.; Ferreira, J.L.N.; Secaf, E.

    1987-01-01

    The use of computerized tomography as a method for evaluating the pulmonary hilum and its application in the diagnosis of endobronchial lesions, hilar masss, contiguous involvement of the mediastinum by hilar mass, and vascular hilar lesions are discussed. A comparative evaluation between conventional tomograms and computerized tomography is presented. (M.A.C.) [pt

  11. Celebral computerized tomography

    International Nuclear Information System (INIS)

    Lofteroed, B.; Sortland, O.

    1985-01-01

    Indications for cerebral computerized tomography (CT) and the diagnostic results from this examination are evaluated in 127 children. Pathological changes were found in 31 children, mostly based on such indications as increasing head size, suspicion of brain tumor, cerebral paresis, delayed psychomotor development and epileptic seizures. A list of indications for CT in children is given

  12. Direct coronary and sagittal computerized tomography of the pelvis

    International Nuclear Information System (INIS)

    Maier, W.; Bargon, G.

    1981-01-01

    Whereas quite a number of reports have been published on direct coronary and sagittal computed tomography of the cranium, no extensive experience has been collected on multidimensional computerized tomography of the pelvis. In this article, the authors report on their preliminary experiences in direct approximately sagittal and coronary computerized tomography of the pelvis in a group of 76 patients. (orig.) [de

  13. Morphological analysis of the vestibular aqueduct by computerized tomography images

    International Nuclear Information System (INIS)

    Marques, Sergio Ricardo; Smith, Ricardo Luiz; Isotani, Sadao; Alonso, Luis Garcia; Anadao, Carlos Augusto; Prates, Jose Carlos; Lederman, Henrique Manoel

    2007-01-01

    Objective: In the last two decades, advances in the computerized tomography (CT) field revise the internal and medium ear evaluation. Therefore, the aim of this study is to analyze the morphology and morphometric aspects of the vestibular aqueduct on the basis of computerized tomography images (CTI). Material and method: Computerized tomography images of vestibular aqueducts were acquired from patients (n = 110) with an age range of 1-92 years. Thereafter, from the vestibular aqueducts images a morphometric analysis was performed. Through a computerized image processing system, the vestibular aqueduct measurements comprised of its area, external opening, length and the distance from the vestibular aqueduct to the internal acoustic meatus. Results: The morphology of the vestibular aqueduct may be funnel-shaped, filiform or tubular and the respective proportions were found to be at 44%, 33% and 22% in children and 21.7%, 53.3% and 25% in adults. The morphometric data showed to be of 4.86 mm 2 of area, 2.24 mm of the external opening, 4.73 mm of length and 11.88 mm of the distance from the vestibular aqueduct to the internal acoustic meatus, in children, and in adults it was of 4.93 mm 2 , 2.09 mm, 4.44 mm, and 11.35 mm, respectively. Conclusions: Computerized tomography showed that the vestibular aqueduct presents high morphological variability. The morphometric analysis showed that the differences found between groups of children and adults or between groups of both genders were not statistically significant

  14. Development and prospects of X-ray computerized tomography. I

    International Nuclear Information System (INIS)

    Dobes, V.

    1985-01-01

    The history and developmental trends are described of X-ray computerized tomography (CT) as are its applications in clinical practise. Suitable criteria and economic aspects are proposed for the choice of CT systems. The types are listed and described of X-ray CT systems, including brain, whole-body, mobile and special systems. A table is given showing available specifications (types of detectors, X-ray source, resolution, configuration, scan angles, scan fields, image reconstruction, etc.) for machines by different companies. (M.D.)

  15. High-resolution computed tomography findings in pulmonary Langerhans cell histiocytosis

    Energy Technology Data Exchange (ETDEWEB)

    Rodrigues, Rosana Souza [Universidade Federal do Rio de Janeiro (HUCFF/UFRJ), RJ (Brazil). Hospital Universitario Clementino Fraga Filho. Unit of Radiology; Capone, Domenico; Ferreira Neto, Armando Leao [Universidade do Estado do Rio de Janeiro (UERJ), Rio de Janeiro, RJ (Brazil)

    2011-07-15

    Objective: The present study was aimed at characterizing main lung changes observed in pulmonary Langerhans cell histiocytosis by means of high-resolution computed tomography. Materials and Methods: High-resolution computed tomography findings in eight patients with proven disease diagnosed by open lung biopsy, immunohistochemistry studies and/or extrapulmonary manifestations were retrospectively evaluated. Results: Small rounded, thin-walled cystic lesions were observed in the lung of all the patients. Nodules with predominantly peripheral distribution over the lung parenchyma were observed in 75% of the patients. The lesions were diffusely distributed, predominantly in the upper and middle lung fields in all of the cases, but involvement of costophrenic angles was observed in 25% of the patients. Conclusion: Comparative analysis of high-resolution computed tomography and chest radiography findings demonstrated that thinwalled cysts and small nodules cannot be satisfactorily evaluated by conventional radiography. Because of its capacity to detect and characterize lung cysts and nodules, high-resolution computed tomography increases the probability of diagnosing pulmonary Langerhans cell histiocytosis. (author)

  16. Results of CT brain examinations in cerebrovascular emergency. [computerized tomography

    Energy Technology Data Exchange (ETDEWEB)

    Pinta, Z; Dolansky, J; Sorfova, J; Jerie, T

    1987-07-01

    Experience is briefly reported with CT (computerized tomography) diagnosis of cerebrovascular emergencies. It is pointed out that the introduction of computerized tomography greatly improved and made more accurate the diagnosis of focal ischemias and revealed significant differences in the foci of ischemia in hypertension patients and atherosclerosis patients without hypertension, and showed a higher incidence of intracerebral and subarachnoidal hemorrhages than previously thought. It is believed that knowledge gained thanks to CT (computerized tomography) will be of benefit to the primary and secondary prevention of cerebrovascular ischemias. (L.O.). 1 fig., 5 refs.

  17. Diagnostics of neuromuscular diseases with the aid of computerized tomography

    Energy Technology Data Exchange (ETDEWEB)

    Visser, M de; Verbeeten, Jr, B J

    1988-06-04

    In this article the diagnosis of neuromuscular diseases with the aid of computerized tomography is treated. Computerized tomography of skeletal muscles give no information which is pathognomonic for particular diseases. But the technique can be used in the following aspects: to choose a muscle for a biopsy; when it is not possible to examine the function of a muscle, a CT scan can visualize morphological deviations; in the differentiation of muscle hypertrophy and pseudo-hypertrophy. For some cases as Becker-type muscular dystrophy, facioscapulohumeral dystrophy and Kugelberg-Welander type spinal muscular atrophy computerized tomography gives characteristic images. 10 refs.; 6 figs.

  18. Diagnostics of neuromuscular diseases with the aid of computerized tomography

    International Nuclear Information System (INIS)

    Visser, M. de; Verbeeten, B.J. Jr.

    1988-01-01

    In this article the diagnosis of neuromuscular diseases with the aid of computerized tomography is treated. Computerized tomography of skeletal muscles give no information which is pathognomonic for particular diseases. But the technique can be used in the following aspects: to choose a muscle for a biopsy; when it is not possible to examine the function of a muscle, a CT scan can visualize morphological deviations; in the differentiation of muscle hypertrophy and pseudo-hypertrophy. For some cases as Becker-type muscular dystrophy, facioscapulohumeral dystrophy and Kugelberg-Welander type spinal muscular atrophy computerized tomography gives characteristic images. 10 refs.; 6 figs

  19. Efficiency of computerized tomography in comparison with other neuroradiological investigation methods

    International Nuclear Information System (INIS)

    Kretzschmar, H.

    1979-01-01

    Computerized tomography is considered to be a decisive and the most reliable investigation method for the diagnosis of cerebral tumors. The rate of detection of intracranial blastomas is over 90%. Supratentorial growths are more easy to prove than tumors at the posterior cranial fossa. In the group of patients examined, 97.3% of the cerebral tumors were confirmed by computerized tomography: 98.7% of these were located above the tentorium and 89.3% under the tentorium. But the diagnostic value of computerized tomography is not only due to the high growth detection rate but also to its informative power as regards the position of growths in relation to vital centres, the type of the blastomas and their space-occupying effect. Thus this investigation method permits to evaluate the complex ''space occupation'' at one glance. By the angiographic method cerebral growths are confirmed in 86% of the cases; 88.6% of these are located above the tentorium. (orig.) [de

  20. Computerized tomography in atypical Pott's disease

    International Nuclear Information System (INIS)

    Cabrera, M.N.B.; Wang, E.H.M.

    1993-01-01

    Classical Pott's disease is described as a two-vertebrae disease with the destruction of the intervening invertebral disc. Computerized tomography has been used in the differential diagnosis of spine infections and neoplasms. We reviewed CT scans of patients seen at the Philippine General Hospital over a two-year period with atypical presentations of atypical tuberculous spondylitis. We used the computerized tomography findings described as characteristic of classical Pott's disease as criteria in evaluating the CT scans of patients diagnosed to have Atypical Pott's Disease. Although the number of patients prevented sensitivity and specificity studies to be done, our results strongly suggest that the same CT criteria used to diagnose Classical Pott's Disease may also be used to diagnose Pott's disease in its atypical form. (Author.). 13 refs

  1. Micro-radiography and micro-computerized tomography with absorption and phase contrast for materials characterization; Mikro-Radiografie und Mikro-Computertomografie mit Absorptions- und Phasenkontrast fuer die Materialcharakterisierung

    Energy Technology Data Exchange (ETDEWEB)

    Kastner, Johann [FH Oberoesterreich, Wels (Austria)

    2017-08-01

    The contribution describes modern techniques in micro-radiography and micro-computerized tomography for materials characterization using absorption and phase contrast. Using micro- and nano-focus tubes and adequate high.-resolution detectors it is possible to reach resolutions significantly below 1 micron. The CT technology allows in-situ deformation testing to study the damaging mechanism of materials. The application of the Talbot-Lau interferometer with CT a differential phase contrast tomography is available. Dark-field tomography is used to study individual carbon fiber bundles in carbon fiber reinforced laminates.

  2. Computerized abdominal tomography in Wilson's disease

    Energy Technology Data Exchange (ETDEWEB)

    Tsuchikura, Keiko; Ogawa, Teruyuki; Nakajima, Akihisa; Ono, Yasuhiko

    1986-05-01

    Cranial and abdominal computerized tomography (CT) was performed in a 10-year-old boy with Wilson's disease complicated by liver cirrhosis. Abdominal CT showed diffuse high density areas over the whole part of the liver propably due to copper sediments, although there was no abnormal cranial CT findings. Decreased high density area of the liver was seen 60 days after the administration of D-penicillamine, suggesting the excretion of copper from the liver. Abdominal CT, as well as cranial CT, may be of help to diagnose Wilson's disease and evaluate therapeutic effects. (Namekawa, K.).

  3. Radiation protection in computerized tomography diagnostics; Strahlenschutz in der Computertomografie

    Energy Technology Data Exchange (ETDEWEB)

    Grust, Andreas [Radiologie am Hauptbahnhof, Duesseldorf (Germany)

    2012-11-01

    The essential advantage of computerized tomography (CT) compared to projecting radiographic techniques is the display of organs free of superposition using a 3D data set and additional enhanced contrast resolution. CT is a mostly objective and examination-independent technique that has developed towards an indispensable tool for tumor diagnostics and traumatology. With respect to the total amount of X-ray diagnostic examinations CT is a rather seldom used technique, nevertheless causing a disproportionately high amount of the collective effective dose of the German population. This disadvantage triggers the necessity to work on a radiation dose reduction. The author discusses the issues X-ray tube current reduction, layer thickness, pitch factor, scan length, dose modulation, adaptive collimation, and iterative reconstruction.

  4. Staging of bronchogenic carcinoma by computerized tomography

    International Nuclear Information System (INIS)

    Sommer, B.; Bauer, W.M.; Rath, M.; Fenzl, G.; Stelter, W.J.; Lissner, J.

    1981-01-01

    It was possible to check the information obtained by CT scanning in 36 patients out of 49 who had been subjected to computerized tomography, in respect of the extension of the primary tumour (T stage), and in 25 patients in respect of the degree of mediastinal lymphatic node involvement (N stage). In all 49 patients, the presence of bronchogenic carcinoma had been safely established. In 97% of the cases, assessment of the extension of the primary tumour was found to be correct. Assessment of the N stage, however, is more problematic, since detection of mediastinal lymphatic nodes by computerized tomography does not necessarily tell us something about their metastatic involvement. If all recognizable lymphatic nodes are interpreted as potential metastases, we have no false negative but 61% false positive results because of the frequency of postinflammatory or anthracotic lymphatic nodes. In case of exclusive assessment of lymphatic node enlargement above 1 cm diameter, the rate of metastatic nodes increases considerably (83%). Computerized tomography is definitely superior to all roentgenological methods in assessing the stage of a bronchogenic carcinoma; hence, it could occupy a key position in determining the diagnostic and therapeutic approach in patients with this disease. (orig.) [de

  5. High resolution positron tomography

    International Nuclear Information System (INIS)

    Brownell, G.L.; Burnham, C.A.

    1982-01-01

    The limits of spatial resolution in practical positron tomography are examined. The four factors that limit spatial resolution are: positron range; small angle deviation; detector dimensions and properties; statistics. Of these factors, positron range may be considered the fundamental physical limitation since it is independent of instrument properties. The other factors are to a greater or lesser extent dependent on the design of the tomograph

  6. High resolution CT in diffuse lung disease

    International Nuclear Information System (INIS)

    Webb, W.R.

    1995-01-01

    High resolution CT (computerized tomography) was discussed in detail. The conclusions were HRCT is able to define lung anatomy at the secondary lobular level and define a variety of abnormalities in patients with diffuse lung diseases. Evidence from numerous studies indicates that HRCT can play a major role in the assessment of diffuse infiltrative lung disease and is indicate clinically (95 refs.)

  7. High resolution CT in diffuse lung disease

    Energy Technology Data Exchange (ETDEWEB)

    Webb, W R [California Univ., San Francisco, CA (United States). Dept. of Radiology

    1996-12-31

    High resolution CT (computerized tomography) was discussed in detail. The conclusions were HRCT is able to define lung anatomy at the secondary lobular level and define a variety of abnormalities in patients with diffuse lung diseases. Evidence from numerous studies indicates that HRCT can play a major role in the assessment of diffuse infiltrative lung disease and is indicate clinically (95 refs.).

  8. Computerized tomography of gall bladder cancer

    International Nuclear Information System (INIS)

    Todua, F.I.; Karmazanovskij, G.G.

    1989-01-01

    The authors have summed up the experience in the use of computerized tomography (CT) in diagnosis of gall bladder cancer. The investigation of 17 patients with cancer of this site showed a high informative value of the method. A retrospective comparative study of the results of CT and surgical interventions was carried out. It has been concluded that CT makes it possible not only to diagnose malignant lesions of the bile ducts but also to assess a possible scope of a forthcoming operation

  9. Comparison of computerized tomography to sonography, applied in diseases of the pancreas

    International Nuclear Information System (INIS)

    Kluge, K.

    1982-01-01

    The examination results of 418 patients whose epigastria had been examined both by computerized tomography and sonography over 1 week in the time from beginning January 1978 until and of July 1979 were compared with regard to the imaging of the pancreas, reliability, and the specificity and sensitivity in establishing the diagnosis. For the sonographic examination, a compound and a real-time unit were used; the computerized tomography was carried out by means of an equipment of the 3rd generation with a scan time of 4 sec. The screening of the pancreas was significantly better using computerized tomography (99.3% US. 84% with US). As for accuracy, computerized tomography had 92.5% exact diagnoses versus 79.9% obtained by sonography. If, however, we look at the cases in which the pancreas could be screened with both methods the accuracy was almost the same (93.7 CT and 93.3% US). Specificity was almost of the same quality, however, the method of computerized tomography with 0.963 was slightly better than ultrasound with 0.943. As for sensitivity, sonography with 0.838 was better than CT with 0.721. The reason for that is the fact that a big part of the chronic pancreatites (30.3%) were not recognized by means of computerized tomography. (orig.) [de

  10. Refinement procedure for the image alignment in high-resolution electron tomography

    International Nuclear Information System (INIS)

    Houben, L.; Bar Sadan, M.

    2011-01-01

    High-resolution electron tomography from a tilt series of transmission electron microscopy images requires an accurate image alignment procedure in order to maximise the resolution of the tomogram. This is the case in particular for ultra-high resolution where even very small misalignments between individual images can dramatically reduce the fidelity of the resultant reconstruction. A tomographic-reconstruction based and marker-free method is proposed, which uses an iterative optimisation of the tomogram resolution. The method utilises a search algorithm that maximises the contrast in tomogram sub-volumes. Unlike conventional cross-correlation analysis it provides the required correlation over a large tilt angle separation and guarantees a consistent alignment of images for the full range of object tilt angles. An assessment based on experimental reconstructions shows that the marker-free procedure is competitive to the reference of marker-based procedures at lower resolution and yields sub-pixel accuracy even for simulated high-resolution data. -- Highlights: → Alignment procedure for electron tomography based on iterative tomogram contrast optimisation. → Marker-free, independent of object, little user interaction. → Accuracy competitive with fiducial marker methods and suited for high-resolution tomography.

  11. Computerized tomography of kidneys in long-term dialysis patients

    International Nuclear Information System (INIS)

    Srp, A.; Merta, M.; Sulkova, S.

    1990-01-01

    A cohort is presented of 21 patients with irreversible kidney failure who were examined by computerized tomography in 1986-1987. The mean period of dialysis programme was 5.7 years, chronic glomerulonephritis and interstitial nephritis were the basic conditions. According to the results of computerized tomography, the patients were divided into four groups: 1. the presence of cysts or tumors was not established, 2. multiplecysts were found in bilateral location, 3. less than 3 cysts were found, 4. kidney tumor was diagnosed. The factor causing the development of the cysts was not identified. It is presumed that the disease is caused by a biologically active substance which is not efficiently dialyzed. The examination of the kidneys is recommended in patients in the stage of chronic kidney insufficiency and particularly in patients on dialysis for a long period of time. The recommended examination uses computerized tomography, and attention should be given to the possible occurence of acquired cystic disease or kidney tumors. (author). 6 figs., 8 refs

  12. Case of neurosarcoidosis monitored by computerized tomography

    Energy Technology Data Exchange (ETDEWEB)

    Kubota, T; Kimura, M; Komai, T; Yamamoto, S; Yamamura, I [Kanazawa Univ. (Japan). School of Medicine

    1979-12-01

    A 21-year-old man complaining of impaired visual acuity was admitted to the hospital. Physical examinations showed asymptomatic bilateral hilar lymphadenopathy and cardiomyopathy. Neurological findings disclosed left blindness and right temporal hemianopsia. Computerized tomography, pneumoencephalography and carotid angiography revealed a suprasellar mass. After the admission, the following symptoms deteriorated rapidly: diabetes insipidus, anterior pituitary dysfunction, visual loss of the right eye and hepatomegaly, subsequently consciousness disorder developed during a month though he was given steroids. The more deteriorated the clinical course, the larger the suprasellar mass with expanding hydrocephalus in repeated computerized tomographies. After the ventriculo-peritoneal shunt operation, consciousness improved. Diabetes insipidus also improved after Diabenese administration. On the operation, adhesive arachnoiditis over all the frontotemporal cortex and swollen purplishly red optic chiasm were exposed. Microscopically the specimen from the optic chiasm evidenced a sarcoid granuloma which composed of epitheroid cells, lymphocytes and multi-nucleated giant cells with numerous hemosiderin droplets. The specimen from the surface of the left frontal lobe showed thick fibrosis in the subarachnoid space. By steroids therapy, diabetes insipidus and hepatomegaly disappeared five months after the admission, whereas blindness never recovered. He died of developed status epilepticus eleven months after the admission. The authors reviewed neuroradiological findings of neurocarcoidosis based on pathological findings in the literature, and emphasized that computerized tomography was the most useful for diagnosis and treatment of neurosarcoidosis.

  13. New detector developments for high resolution positron emission tomography

    International Nuclear Information System (INIS)

    Ziegler, S.I.; Pichler, B.; Lorenz, E.

    1998-01-01

    The strength of quantitative, functional imaging using positron emission tomography, specially in small animals, is limited due to the spatial resolution. Therefore, various tomograph designs employing new scintillators, light sensors, or coincidence electronic are investigated to improve resolution without losses in sensitivity. Luminous scintillators with short light decay time in combination with novel readout schemes using photomultipliers or semiconductor detectors are currently tested by several groups and are implemented in tomographs for small animals. This review summarises the state of development in high resolution positron emission tomography with a detailed description of a system incorporating avalanche photodiode arrays and small scintillation crystals. (orig.) [de

  14. Recurrent lymph node metastases after craniocervical tumours: Computerized tomography

    International Nuclear Information System (INIS)

    Helmberger, H.; Lenz, M.; Kersting-Sommerhoff, B.; Bautz, W.; Kretz, S.

    1992-01-01

    A total of 544 CT examinations of the craniocervical region carried out in 231 patients were analyzed on a retrospective basis in order to assess the clinical value of contrast-enhanced computerized tomography, being carried out either for comparison with or in combination with clinical control examinations, in the post-therapeutic surveillance of patients treated for craniocervical tumours. The diagnostic accuracy attained with computerized tomography in the detection of recurrent lymph node metastases was 95% and thus superior to that determined for clinical control examinations (80%). (orig./GDG) [de

  15. Density evaluation by computerized tomography in plain soils over different manipulation systems

    International Nuclear Information System (INIS)

    Pedrotti, Alceu

    1996-08-01

    The objective of this paper is the evaluation of a plain soil density in different culture systems determined by X ray computerized tomography.It was observed a larger variation in densities in soils profiles analysed. The identification of layers is better utilising computerized tomography than others technic

  16. High-resolution computed tomography and histopathological findings in hypersensitivity pneumonitis: a pictorial essay

    Energy Technology Data Exchange (ETDEWEB)

    Torres, Pedro Paulo Teixeira e Silva; Moreira, Marise Amaral Reboucas; Silva, Daniela Graner Schuwartz Tannus; Moreira, Maria Auxiliadora do Carmo [Universidade Federal de Goias (UFG), Goiania, GO (Brazil); Gama, Roberta Rodrigues Monteiro da [Hospital do Cancer de Barretos, Barretos, SP (Brazil); Sugita, Denis Masashi, E-mail: pedroptstorres@yahoo.com.br [Anapolis Unievangelica, Anapolis, GO (Brazil)

    2016-03-15

    Hypersensitivity pneumonitis is a diffuse interstitial and granulomatous lung disease caused by the inhalation of any one of a number of antigens. The objective of this study was to illustrate the spectrum of abnormalities in high-resolution computed tomography and histopathological findings related to hypersensitivity pneumonitis. We retrospectively evaluated patients who had been diagnosed with hypersensitivity pneumonitis (on the basis of clinical-radiological or clinical-radiological-pathological correlations) and had undergone lung biopsy. Hypersensitivity pneumonitis is clinically divided into acute, subacute, and chronic forms; high-resolution computed tomography findings correlate with the time of exposure; and the two occasionally overlap. In the subacute form, centrilobular micronodules, ground glass opacities, and air trapping are characteristic high-resolution computed tomography findings, whereas histopathology shows lymphocytic inflammatory infiltrates, bronchiolitis, variable degrees of organizing pneumonia, and giant cells. In the chronic form, high-resolution computed tomography shows traction bronchiectasis, honeycombing, and lung fibrosis, the last also being seen in the biopsy sample. A definitive diagnosis of hypersensitivity pneumonitis can be made only through a multidisciplinary approach, by correlating clinical findings, exposure history, high-resolution computed tomography findings, and lung biopsy findings. (author)

  17. The clinical impact of high resolution computed tomography in patients with respiratory disease

    International Nuclear Information System (INIS)

    Screaton, Nicholas J.; Tasker, Angela D.; Flower, Christopher D.R.; Miller, Fiona N.A.C.; Patel, Bipen D.; Groves, Ashley; Lomas, David A.

    2011-01-01

    High resolution computed tomography is widely used to investigate patients with suspected diffuse lung disease. Numerous studies have assessed the diagnostic performance of this investigation, but the diagnostic and therapeutic impacts have received little attention. The diagnostic and therapeutic impacts of high resolution computed tomography in routine clinical practice were evaluated prospectively. All 507 referrals for high-resolution computed tomography over 12 months in two centres were included. Requesting clinicians completed questionnaires before and after the investigation detailing clinical indications, working diagnoses, confidence level in each diagnosis, planned investigations and treatments. Three hundred and fifty-four studies on 347 patients had complete data and were available for analysis. Following high-resolution computed tomography, a new leading diagnosis (the diagnosis with the highest confidence level) emerged in 204 (58%) studies; in 166 (47%) studies the new leading diagnosis was not in the original differential diagnosis. Mean confidence in the leading diagnosis increased from 6.7 to 8.5 out of 10 (p < 0.001). The invasiveness of planned investigations increased in 23 (7%) studies and decreased in 124 (35%) studies. The treatment plan was modified after 319 (90%) studies. Thoracic high-resolution computed tomography alters leading diagnosis, increases diagnostic confidence, and frequently changes investigation and management plans. (orig.)

  18. Detectors for high resolution dynamic positron emission tomography

    International Nuclear Information System (INIS)

    Derenzo, S.E.; Budinger, T.F.; Huesman, R.H.

    1985-01-01

    Tomography is the technique of producing a photographic image of an opaque specimen by transmitting a beam of x-rays or gamma rays through the specimen onto an adjacent photographic film. The image results from variations in thickness, density, and chemical composition, of the specimen. This technique is used to study the metabolism of the human brain. This article examines the design of equipment used for high resolution dynamic positron emission tomography. 27 references, 5 figures, 3 tables

  19. Preoperative localization of parathyroid tumor by computerized tomography

    International Nuclear Information System (INIS)

    Kan, Seiji; Hiraishi, Koji; Nakamura, Shoichiro; Yamamoto, Schuzo; Odachi, Motoaki; Yamashita, Toshiyuki.

    1984-01-01

    Five patients of primary hyperparathyroidism with urolithiasis underwent CT-scanning for the preoperative localization of parathyroid tumor. The tumor was identified in all patients but one, who had a multiple adenomatous goiter. In this case, postoperative observation of the CT-scan revealed the parathyroid tumor. It appears that if the size of the parathyroid tumor is about 1cm in diameter, there is a high possibility of preoperative localization by computerized tomography. (author)

  20. 3D observation of the solidified structures by x-ray micro computerized tomography

    International Nuclear Information System (INIS)

    Yasuda, Hideyuki; Ohnaka, Itsuo; Tsuchiyama, Akira; Nakano, Tsukasa; Uesugi, Kentaro

    2003-01-01

    The high flux density of the monochromatized and well-collimated X-ray and the high-resolution detector provide a new 3D observation tool for microstructures of metallic alloys and ceramics. The X-ray micro computerized tomography in BL47XU of SPring-8 (SP-μCT) was applied to observe microstructures produced through the eutectic reaction for Sn-based alloys and an Al 2 O 3 -Y 2 O 3 oxide system. The constituent phases in the eutectic structures were three-dimensionally identified, in which the lamellar spacing ranged from several to 10 μm. Since the 3D structure of the unidirectionally solidified specimens contains history of the eutectic structure formation, the 3D structure obtained by SP-μCT gives useful information to consider the microstructure evolution. (author)

  1. Diffuse nesidioblastosis diagnosed on a Ga-68 DOTATATE positron emission tomography/computerized tomography

    International Nuclear Information System (INIS)

    Arun, Sasikumar; Mittal, Bhagwant Rai; Shukla, Jaya; Bhattacharya, Anish; Kumar, Praveen

    2013-01-01

    The authors describe a 50 days old pre-term infant with persistent hyperinsulinemic hypoglycemia of infancy in whom 68 Ga DOTATATE positron emission tomography/computerized tomography scan showed diffusely increased tracer uptake in the entire pancreas with no abnormal tracer uptake anywhere else in the body, suggestive of a diffuse variant of nesidioblastosis. (author)

  2. Patient surface doses in computerized tomography examinations

    International Nuclear Information System (INIS)

    Vekic, B; Kovacevic, S.; Ranogajec-Komor, M.; Duvnjak, N.; Marusic, P.; Anic, P.; Dolencic, P.

    1996-01-01

    The diagnostic value of computerized tomography has increased due to very rapid technical advances in both equipment and techniques. When the CT scanners were introduced, a significant problem for the specification of the radiation dose imparted to the patient undergoing CT examination has been created. In CT, the conditions of exposure are quite different from those in conventional X-ray imaging. CT procedure involves the continuous tomography of thin layers. Some of these layers touch each other while others overlap. The radiation doses received by patients can vary considerably. In addition to the radiation from the collimated primary beam, patients are exposed to significant scattered doses in unpredictable amounts. Every effort should be made to keep these doses to a reasonable minimum, without sacrificing the image quality. The aims of this work were to determine the surface doses delivered to various organs of patients during various computerized tomography examinations (head, thorax, kidney, abdomen and pelvis). Particular attention was directed to the precise determination of doses received by the eyes (during CT of head) and gonads (during CT of pelvis and lower abdomen) since these organs can be near or even in the primary X-ray beam

  3. A case of neurosarcoidosis monitored by computerized tomography

    International Nuclear Information System (INIS)

    Kubota, Toshihiko; Kimura, Makoto; Komai, Toshio; Yamamoto, Shinjiro; Yamamura, Itaru

    1979-01-01

    A 21-year-old man complaining of impaired visual acuity was admitted to the hospital. Physical examinations showed asymptomatic bilateral hilar lymphadenopathy and cardiomyopathy. Neurological findings disclosed left blindness and right temporal hemianopsia. Computerized tomography, pneumoencephalography and carotid angiography revealed a suprasellar mass. After the admission, the following symptoms deteriorated rapidly: diabetes insipidus, anterior pituitary dysfunction, visual loss of the right eye and hepatomegaly, subsequently consciousness disorder developed during a month though he was given steroids. The more deteriorated the clinical course, the larger the suprasellar mass with expanding hydrocephalus in repeated computerized tomographies. After the ventriculo-peritoneal shunt operation, consciousness improved. Diabetes insipidus also improved after Diabenese administration. On the operation, adhesive arachnoiditis over all the frontotemporal cortex and swollen purplishly red optic chiasm were exposed. Microscopically the specimen from the optic chiasm evidenced a sarcoid granuloma which composed of epitheroid cells, lymphocytes and multi-nucleated giant cells with numerous hemosiderin droplets. The specimen from the surface of the left frontal lobe showed thick fibrosis in the subarachnoid space. By steroids therapy, diabetes insipidus and hepatomegaly disappeared five months after the admission, whereas blindness never recovered. He died of developed status epilepticus eleven months after the admission. The authors reviewed neuroradiological findings of neurocarcoidosis based on pathological findings in the literature, and emphasized that computerized tomography was the most useful for diagnosis and treatment of neurosarcoidosis. (author)

  4. Acute renal failure following contrast injection for head computerized tomography in two patients with diabetic nephropathy

    International Nuclear Information System (INIS)

    Matsunaga, Hiroshi; Sando, Hiroyuki; Nunokawa, Tomoo; Murakami, Tooru; Miyakawa, Yuzo

    1981-01-01

    Two cases of diabetes mellitus with renal and retinal involvement developed acute renal failure after undergoing head computerized tomography. The first case was a 62-year-old male who had been diagnosed as having diabetes 25 years before. He had diabetic retinopathy of Scott IIIb. Before head computerized tomography, the serum BUN was 37 mg/dl, and creatinine was 4.1 mg/dl. Oliguria began immediately after the scanning and confinued for 48 hr. The serum levels of BUN and creatinine rose to 106 and 7.7 mg/dl, respectively. Case 2 was a 49-year-old male who had been diagnosed as having diabetes 15 years before. He showed Scott IIb and IV retinopathy. The BUN and creatinine levels in the serum were 32 and 2.3 mg/dl, respectively. After receiving head computerized tomography, he developed oliguria and remained oliguric for 48 hr. During that period, the serum levels of BUN and creatinin were elevated to 112 and 7.5 mg/dl, respectively. Fortunately, both of these patients recovered from the oliguria without resorting to hemodialysis. The iodine contrast medium routinely used for contrast enhancement in the head computerized tomography was implicated in the acute renal failure of these patients. Only elevn cases have so far been reported in the literature who developed acute renal failure following computerized tomography. In view of the three or four times greater dosis of iodine contrast medium employed in computerized tomography compared to intravenous pyelography, the acute incidence of such complications might be much higher. Among the thirteen cases including the two reported here, as many as eight were diabetic. It is well recongnized that the incidence of acute renal failure after intravenous pyelography is particularly high in cases of diabetic nephropathy. (author)

  5. High resolution and high speed positron emission tomography data acquisition

    International Nuclear Information System (INIS)

    Burgiss, S.G.; Byars, L.G.; Jones, W.F.; Casey, M.E.

    1986-01-01

    High resolution positron emission tomography (PET) requires many detectors. Thus, data collection systems for PET must have high data rates, wide data paths, and large memories to histogram the events. This design uses the VMEbus to cost effectively provide these features. It provides for several modes of operation including real time sorting, list mode data storage, and replay of stored list mode data

  6. Computerized tomography in radiodiagnosis of pneumonia

    International Nuclear Information System (INIS)

    Degtyareva, I.A.; Mamaev, V.V.; Savchenko, A.P.

    1989-01-01

    Experience in the use of computerized tomography (CT) in combined radiodiagnosis of pneumonia was analysed. It has been concluded that CT objectively reflects morphological inflammatory changes and permits their all-round assessment over time. The diagnosis of pneumonia in CT is based on classical x-ray symptoms. As compared to survery radiography CT reveals symptoms of pneumonia to the full at earlier stages. CT is an important additional method of investigation of inflammatory pulmonary diseases but it should not be used separately without survey radiography. In a majority of cases when CT is performed there is no need in x-ray tomography

  7. Method of evaluation of diagnostics reference levels in computerized tomography

    International Nuclear Information System (INIS)

    Vega, Walter Flores

    1999-04-01

    Computerized tomography is a complex technique with several selectable exposition parameters delivering high doses to the patient. In this work it was developed a simple methodology to evaluate diagnostic reference levels in computerized tomography, using the concept of Multiple Scan Average Dose (MSAD), recently adopted by the Health Ministry. For evaluation of the MSAD, a dose distribution was obtained through a measured dose profile on the axial axis of a water phantom with thermoluminescence dosemeters, TLD-100, for different exam technique. The MSAD was evaluated hrough two distinct methods. First, it was evaluated by the integration of the dose profile of a single slice and, second, obtained by the integration on central slice of the profile of several slices. The latter is in of accordance with the ionization chamber method, suggesting to be the most practical method of dose evaluation to be applied in the diagnostic reference level assessment routine for CT, using TLDs. (author)

  8. Evaluation of the absorbed dose in odontological computerized tomography

    International Nuclear Information System (INIS)

    Legnani, Adriano; Schelin, Hugo R.; Rocha, Anna Silvia P.S. da; Khoury, Helen J.

    2011-01-01

    This paper evaluated the absorbed dose at the surface entry known as 'cone beam computed tomography' (CBCT) in odontological computerized tomography. Examination were simulated with CBCT for measurements of dose. A phantom were filled with water, becoming scatter object of radiation. Thermoluminescent dosemeters were positioned on points correspondent to eyes and salivary glands

  9. A method for volume determination of the orbit and its contents by high resolution axial tomography and quantitative digital image analysis.

    Science.gov (United States)

    Cooper, W C

    1985-01-01

    The various congenital and acquired conditions which alter orbital volume are reviewed. Previous investigative work to determine orbital capacity is summarized. Since these studies were confined to postmortem evaluations, the need for a technique to measure orbital volume in the living state is presented. A method for volume determination of the orbit and its contents by high-resolution axial tomography and quantitative digital image analysis is reported. This procedure has proven to be accurate (the discrepancy between direct and computed measurements ranged from 0.2% to 4%) and reproducible (greater than 98%). The application of this method to representative clinical problems is presented and discussed. The establishment of a diagnostic system versatile enough to expand the usefulness of computerized axial tomography and polytomography should add a new dimension to ophthalmic investigation and treatment.

  10. High resolution tomography using analog coding

    International Nuclear Information System (INIS)

    Brownell, G.L.; Burnham, C.A.; Chesler, D.A.

    1985-01-01

    As part of a 30-year program in the development of positron instrumentation, the authors have developed a high resolution bismuth germanate (BGO) ring tomography (PCR) employing 360 detectors and 90 photomultiplier tubes for one plane. The detectors are shaped as trapezoid and are 4 mm wide at the front end. When assembled, they form an essentially continuous cylindrical detector. Light from a scintillation in the detector is viewed through a cylindrical light pipe by the photomultiplier tubes. By use of an analog coding scheme, the detector emitting light is identified from the phototube signals. In effect, each phototube can identify four crystals. PCR is designed as a static device and does not use interpolative motion. This results in considerable advantage when performing dynamic studies. PCR is the positron tomography analog of the γ-camera widely used in nuclear medicine

  11. High resolution muon computed tomography at neutrino beam facilities

    International Nuclear Information System (INIS)

    Suerfu, B.; Tully, C.G.

    2016-01-01

    X-ray computed tomography (CT) has an indispensable role in constructing 3D images of objects made from light materials. However, limited by absorption coefficients, X-rays cannot deeply penetrate materials such as copper and lead. Here we show via simulation that muon beams can provide high resolution tomographic images of dense objects and of structures within the interior of dense objects. The effects of resolution broadening from multiple scattering diminish with increasing muon momentum. As the momentum of the muon increases, the contrast of the image goes down and therefore requires higher resolution in the muon spectrometer to resolve the image. The variance of the measured muon momentum reaches a minimum and then increases with increasing muon momentum. The impact of the increase in variance is to require a higher integrated muon flux to reduce fluctuations. The flux requirements and level of contrast needed for high resolution muon computed tomography are well matched to the muons produced in the pion decay pipe at a neutrino beam facility and what can be achieved for momentum resolution in a muon spectrometer. Such an imaging system can be applied in archaeology, art history, engineering, material identification and whenever there is a need to image inside a transportable object constructed of dense materials

  12. Quality criteria for abdominal computerized tomography

    International Nuclear Information System (INIS)

    Huebener, K.H.; Kurtz, B.; Metzger, H.O.F.

    1985-01-01

    Quality, not only in obdominal computerized tomography, is determined by the measurable technical parameters and, to an important extent, also bei individual factors, among which the diagnostic skill and experience of the examiner is one of the most decisive. These individual factors and the part they play with regard to the quality of CT-assisted diagnosis may well equal the technical parameters, as they significantly influence the course of examinations, resulting indications for contrast medium application, and the sensitivity of the diagnosis. The authors are convinced that especially for abdominal CT, standardized examination techniques inevitably would bring down the diagnostic quality. The technical parameters are of equal significance to achieving the diagnostic optimum, and to these parameters one has to count equipment characteristics as well as the data given by the examiner. Exposure time, spatial resolution and density differentiation are given by the equipment specifications but have to be adapted to and optimised to the clinical problems involved in every case. Another important task is that of routine imaging of given anatomic structures, for adequate evaluation of individual conditions. (orig./MG) [de

  13. High-resolution short-exposure small-animal laboratory x-ray phase-contrast tomography

    Science.gov (United States)

    Larsson, Daniel H.; Vågberg, William; Yaroshenko, Andre; Yildirim, Ali Önder; Hertz, Hans M.

    2016-12-01

    X-ray computed tomography of small animals and their organs is an essential tool in basic and preclinical biomedical research. In both phase-contrast and absorption tomography high spatial resolution and short exposure times are of key importance. However, the observable spatial resolutions and achievable exposure times are presently limited by system parameters rather than more fundamental constraints like, e.g., dose. Here we demonstrate laboratory tomography with few-ten μm spatial resolution and few-minute exposure time at an acceptable dose for small-animal imaging, both with absorption contrast and phase contrast. The method relies on a magnifying imaging scheme in combination with a high-power small-spot liquid-metal-jet electron-impact source. The tomographic imaging is demonstrated on intact mouse, phantoms and excised lungs, both healthy and with pulmonary emphysema.

  14. Impact of Multidetector Computerized Tomography (MDCT) On The General Population

    Energy Technology Data Exchange (ETDEWEB)

    Leite, B.B.; Ribeiro, N.C. [Servico de Radiologia, Hospital de Curry Cabral, Rua da Beneficencia, 8, 1069-166 Lisboa (Portugal)

    2009-05-15

    Multidetector computerized tomography (MDCT) appeared in the early 1990s, as a technological evolution of computerized tomography. As one would expect, the evolution continues and, each year, more powerful equipments appear, with new medical applications. However, the general use of this technique has lead to the dramatic increase on the general population irradiation. Special concern is required regarding the most vulnerable groups, like the pediatric population, the pregnant and the young female. Due to a larger awareness of this irradiation risks, some initiatives have been developed, coming from different areas, aiming to maximize the benefit to risk ratio of MDCT. (author)

  15. High-resolution coded-aperture design for compressive X-ray tomography using low resolution detectors

    Science.gov (United States)

    Mojica, Edson; Pertuz, Said; Arguello, Henry

    2017-12-01

    One of the main challenges in Computed Tomography (CT) is obtaining accurate reconstructions of the imaged object while keeping a low radiation dose in the acquisition process. In order to solve this problem, several researchers have proposed the use of compressed sensing for reducing the amount of measurements required to perform CT. This paper tackles the problem of designing high-resolution coded apertures for compressed sensing computed tomography. In contrast to previous approaches, we aim at designing apertures to be used with low-resolution detectors in order to achieve super-resolution. The proposed method iteratively improves random coded apertures using a gradient descent algorithm subject to constraints in the coherence and homogeneity of the compressive sensing matrix induced by the coded aperture. Experiments with different test sets show consistent results for different transmittances, number of shots and super-resolution factors.

  16. Computerized Tomography and its Applications : a Guided Tour

    NARCIS (Netherlands)

    Roerdink, J.B.T.M.

    1992-01-01

    We present a review of the mathematical principles of computerized tomography. Topics treated include the role of the Radon transform and related transforms, inversion formulas, uniqueness, ill-posedness and stability, practical reconstruction algorithms, and various generalizations such as

  17. 10 years of computerized tomography reviewed

    International Nuclear Information System (INIS)

    Duemmling, K.

    1984-01-01

    The history and some highlights of computerized tomography are reviewed. The various technologies employed in the course of CT development are described along with the limitations that led to their disappearance. The problems still to be solved in medicine, the increasing influence of nuclear magnetic resonance, and some scientific aspects have opened up new lines of development which are briefly mentioned. (orig./WU) [de

  18. Quantitative inspection by computerized tomography

    International Nuclear Information System (INIS)

    Lopes, R.T.; Assis, J.T. de; Jesus, E.F.O. de

    1989-01-01

    The computerized Tomography (CT) is a method of nondestructive testing, that furnish quantitative information, that permit the detection and accurate localization of defects, internal dimension measurement, and, measurement and chart of the density distribution. The CT technology is much versatile, not presenting restriction in relation to form, size or composition of the object. A tomographic system, projected and constructed in our laboratory is presented. The applications and limitation of this system, illustrated by tomographyc images, are shown. (V.R.B.)

  19. Pathologic assessment of computerized tomography accuracy for the evaluation of the laryngeal cartilagineous framework in laryngopharyngeal carcinomas

    International Nuclear Information System (INIS)

    Sulfaro, S.; Volpe, R.; Carbone, A.; Barzan, L.; Comoretto, R.

    1989-01-01

    Syxty-six whole-organ sectioned laryngopharyngectomy specimens removed for cancer during a seven-year period were uniformly examined to determine the accuracy of preoperative high resolution computerized tomography (CT) for detection of cartilaginous involvement. Results achived indicate that CT has a high overall specificity (88.2%) but a low sensitivity (47.1%); high false negative rate (26.5%) and a fairly low false-positive rate (5.9%) are observed. Massive cartilage destruction was easily assessed by CT, whereas both small macroscopic and microscopic neoplastic foci of cartilaginous invasion were missed on CT scans. Moreover, false-positive cases were mainly due to proximity of the tumor to the cartilage. Clinical implications of these results are discussed

  20. Sonography and computerized tomography in a comparison in renal mass diseases

    International Nuclear Information System (INIS)

    Brommer, M.

    1981-01-01

    One hundred and thirteen patients with renal mass processes were examined sonographically and by computized tomography. The diagnosis was assured in 32 cases histologically, in 40 cases angiographically clinically and by the course and in 41 cases only clinically and by the course resp. by sonographic and computerized tomography control studies. The accuracy of a hit in sonography is smaller compared with computerized tomography with fast image formation. However, due to its relative safety, it is judged as the most useful technique for a first diagnossis of renal masses after ureographic diagnostic of excreta. A diagnostic procedure is proposed in which the number of necessary angiographies and diagnostic sampling surgery can be considerably reduced. (orig.) [de

  1. Non-Conventional Applications of Computerized Tomography: Analysis of Solid Dosage Forms Produced by Pharmaceutical Industry

    International Nuclear Information System (INIS)

    Martins de Oliveira, Jose Jr.; Germano Martins, Antonio Cesar

    2010-01-01

    X-ray computed tomography (CT) refers to the cross-sectional imaging of an object measuring the transmitted radiation at different directions. In this work, we describe a non-conventional application of computerized tomography: visualization and improvements in the understanding of some internal structural features of solid dosage forms. A micro-CT X-ray scanner, with a minimum resolution of 30 μm was used to characterize some pharmaceutical tablets, granules, controlled-release osmotic tablet and liquid-filled soft-gelatin capsules. The analysis presented in this work are essentially qualitative, but quantitative parameters, such as porosity, density distribution, tablets dimensions, etc. could also be obtained using the related CT techniques.

  2. Forward transformation for high resolution eddy current tomography using whitney elements

    International Nuclear Information System (INIS)

    Szewczyk, R.; Salach, J.; Nowicki, M.; Ruokolainen, J.; Raback, P.

    2014-01-01

    Tomographic methods are intensively developed field of non-destructive testing. The main advantage of this type of NDT method is 3D information concerning the shape of the discontinuities in investigated material. On the other hand, the most common tomography method utilizing X-rays creates the significant risks typical to X-ray technique. As a result, Xray tomography is difficult to use in industry. Introduced to the industry in 2007, the eddy current tomography is safe and cost effective. However, in opposite to X-ray tomography, eddy current tomography requires sophisticated and time consuming inverse transformation creating 2D or 3D view of discontinuities. For this reason solutions presented previously are focused on 2D inverse transformation and exhibit limited resolution. For eddy current tomography, the forward tomographic transformation is most important, which is the base of inverse transformation. This paper presents the novel, fast and cost-effective solution utilizing Whitney elements method for such forward transformation. As a result, new possibilities of development in the area of high resolution 3D eddy current tomography are created. (authors)

  3. Two cases of posterior scleritis and findings of computerized tomography and ultrasonography

    International Nuclear Information System (INIS)

    Ohara, Takakazu; Uji, Yukitaka; Fujioka, Chieko; Mori, Kazuma

    1982-01-01

    Two cases of unilateral posterior scleritis, seen in 56-year-old and 68-year-old females, are reported. Computerized tomography showed characteristic findings, as follows: 1) Thickening of the posterior sclera and surrounding tissue. 2) Irregularity of the posterior wall of the eyeball. 3) Increased radiographic density in the posterior wall of the eyeball. Ultrasonography also suggested thickening of the posterior sclera. Computerized tomography and ultrasonography are considered useful in the diagnosis of posterior scleritis. (author)

  4. Radio astronomical interferometry and x-ray's computerized tomography

    Energy Technology Data Exchange (ETDEWEB)

    Rodriguez, L F [Universidad Nacional Autonoma de Mexico, Mexico City. Inst. de Astronomia

    1982-01-01

    Radio astronomical interferometry and computerized tomography are techniques of great importance for astronomy and medicine, respectively. In this paper we emphasize that both techniques are based on the same mathematical principles, and present them as an example of interaction between basic and applied science.

  5. Lipoid pneumonia in adults: findings on high-resolution computed tomography

    International Nuclear Information System (INIS)

    Marchiori, Edson; Escuissato, Dante L.; Souza Junior, Arthur Soares; Araujo Neto, Cesar; Nobre, Luiz Felipe; Irion, Klaus L.; Rodrigues, Rosana; Mancano, Alexandre Dias; Capone, Domenico; Fialho, Suzane Mansur; Souza, Carolina Althoff

    2007-01-01

    Objective: The present study was aimed at describing the findings on high-resolution computed tomography in patients with exogenous lipoid pneumonia secondary to mineral oil aspiration. Materials and methods: Eight adult patients - four men and four women - with mean age of 69.4 years were studied. All of the patients were users of mineral oil for treating intestinal constipation. High-resolution computed tomography studies of these patients were blindly evaluated by two radiologists. Results: Air-space consolidation with areas of fat density and crazy paving pattern were the most frequent findings. The lesions were bilateral in six cases and unilateral in two. Conclusion: Air-space consolidation with areas of fat density, associated with a clinical history of mineral oil ingestion virtually indicates a diagnosis of exogenous lipoid pneumonia. (author)

  6. Lipoid pneumonia in adults: findings on high-resolution computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    Marchiori, Edson [Universidade Federal Fluminense (UFF), Niteroi, RJ (Brazil). Dept. of Radiology]. E-mail: edmarchiori@gmail.com; Zanetti, Glaucia [Faculdade de Medicina de Petropolis, RJ (Brazil); Escuissato, Dante L. [Universidade Federal do Parana (UFPR), Curitiba, PR (Brazil); Souza Junior, Arthur Soares [Faculdade de Medicina de Sao Jose do Rio Preto (FAMERP), SP (Brazil); Araujo Neto, Cesar [Universidade Federal da Bahia (UFBA), Salvador, BA (Brazil); Nobre, Luiz Felipe [Universidade Federal de Santa Catarina (UFSC), Florianopolis, SC (Brazil); Irion, Klaus L. [The Cardiothoracic Centre NHS Trust, Liverpool (United Kingdom); Rodrigues, Rosana [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil). Hospital Universitario Clementino Fraga Filho (HUCFF); Mancano, Alexandre Dias [Hospital Regional de Taguatinga, Brasilia, DF (Brazil); Capone, Domenico [Universidade Estadual do Rio de Janeiro (UERJ), RJ (Brazil); Fialho, Suzane Mansur [Centro Nuclear da Guanabara, Rio de Janeiro, RJ (Brazil); Souza, Carolina Althoff [University of Ottawa (Canada)

    2007-09-15

    Objective: The present study was aimed at describing the findings on high-resolution computed tomography in patients with exogenous lipoid pneumonia secondary to mineral oil aspiration. Materials and methods: Eight adult patients - four men and four women - with mean age of 69.4 years were studied. All of the patients were users of mineral oil for treating intestinal constipation. High-resolution computed tomography studies of these patients were blindly evaluated by two radiologists. Results: Air-space consolidation with areas of fat density and crazy paving pattern were the most frequent findings. The lesions were bilateral in six cases and unilateral in two. Conclusion: Air-space consolidation with areas of fat density, associated with a clinical history of mineral oil ingestion virtually indicates a diagnosis of exogenous lipoid pneumonia. (author)

  7. A high time and spatial resolution MRPC designed for muon tomography

    Science.gov (United States)

    Shi, L.; Wang, Y.; Huang, X.; Wang, X.; Zhu, W.; Li, Y.; Cheng, J.

    2014-12-01

    A prototype of cosmic muon scattering tomography system has been set up in Tsinghua University in Beijing. Multi-gap Resistive Plate Chamber (MRPC) is used in the system to get the muon tracks. Compared with other detectors, MRPC can not only provide the track but also the Time of Flight (ToF) between two detectors which can estimate the energy of particles. To get a more accurate track and higher efficiency of the tomography system, a new type of high time and two-dimensional spatial resolution MRPC has been developed. A series of experiments have been done to measure the efficiency, time resolution and spatial resolution. The results show that the efficiency can reach 95% and its time resolution is around 65 ps. The cluster size is around 4 and the spatial resolution can reach 200 μ m.

  8. Cranial Computerized Tomography In The Evaluation Of Stroke ...

    African Journals Online (AJOL)

    206 patients clinically diagnosed as stroke / cerebrovascular accidents (CVA) were investigated using computerized tomography (CT) scan. 19 patients (9%) had normal scan. While 20(9.7%) had other lesions including atrophy and tumours. Of the 167 (18. %) patients proven to have suffered a cerebro- vascular accident ...

  9. Computerized tomography in the examination of the orbit

    International Nuclear Information System (INIS)

    Ammerich, H.; Wackenheim, A.; Golabek, R.

    1980-01-01

    The importance of computerized tomography in the ophtalmological diagnosis is discussed. A great value of the information obtained by this not cumbersome method is stressed. The findings achieved this method in the most frequent diseases of the eyeball, orbit and neighbouring anatomical structures are described. (author)

  10. Computerized tomography of adrenal glands in the investigation of Cushing's syn

    International Nuclear Information System (INIS)

    Abucham Filho, J.; Albertotti, C.; Kater, C.E.; Vieira, J.G.H.; Chacra, A.R.

    1983-01-01

    Computerized tomography of the adrenal glands was performed in 10 patients with Cushing's syndrome using a G.E. 8800 CT/T Body Scanner. The tomographic findings of unilateral adrenal masses in 4 patients were confirmed by surgery. In the remaining 6 patients, computerized tomography did not identify any masses, and both glands were well visualized and showed normal shape. In these patients, measurement of the adrenal glands revealed both normal (n=1) and enlarged glands (n=5). The findings of adrenalectomy (n=4) or transphenoidal surgery and follow-up (n=2) established the diagnosis of adrenal phyperplasia in all patients. (Author) [pt

  11. Computerized transverse tomography of vascular lesions of the brain. II. Aneurysms

    International Nuclear Information System (INIS)

    Pressman, B.D.; Gilbert, G.E.; Davis, D.O.

    1975-01-01

    Computerized transverse tomography (CTT) is an excellent screening examination for intracerebral disease. Unfortunately, the detection rate of small aneurysms by this procedure is not high. Nevertheless, CTT may be useful in aneurysm cases since it may indicate the need for further evaluation in patients with associated hematomas, encephalomalacia, or ventricular dilatation, even if the aneurysm itself is not delineated. (U.S.)

  12. Detection of lymph node metastasis in patients with nodal prostate cancer relapse using (18)F/(11)C-choline positron emission tomography/computerized tomography.

    Science.gov (United States)

    Jilg, Cordula A; Schultze-Seemann, Wolfgang; Drendel, Vanessa; Vach, Werner; Wieser, Gesche; Krauss, Tobias; Jandausch, Anett; Hölz, Stefanie; Henne, Karl; Reske, Sven N; Grosu, Anca-L; Weber, Wolfgang A; Rischke, H Christian

    2014-07-01

    prostate cancer relapse with high accuracy and it seems helpful for guiding salvage lymph node dissection. Sensitivity decreases with the size of metastatic infiltration in lymph nodes. This technique detects metastasis in a significant fraction of lymph nodes that are not pathologically enlarged on computerized tomography. Copyright © 2014 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

  13. The limited angle problem in computerized tomography

    International Nuclear Information System (INIS)

    Louis, A.K.

    1984-01-01

    Fast reconstruction formulae in X-ray computerized tomography demand the directions, in which the measurements are taken, to be equally distributed over the whole circle. In many applications data can only be provided in a restricted range. Here the intrinsic difficulties are studied by giving a singular value decomposition of the Radon transform in a restricted range. Practical limitations are deduced. (orig.)

  14. Emission computerized axial tomography from multiple gamma-camera views using frequency filtering.

    Science.gov (United States)

    Pelletier, J L; Milan, C; Touzery, C; Coitoux, P; Gailliard, P; Budinger, T F

    1980-01-01

    Emission computerized axial tomography is achievable in any nuclear medicine department from multiple gamma camera views. Data are collected by rotating the patient in front of the camera. A simple fast algorithm is implemented, known as the convolution technique: first the projection data are Fourier transformed and then an original filter designed for optimizing resolution and noise suppression is applied; finally the inverse transform of the latter operation is back-projected. This program, which can also take into account the attenuation for single photon events, was executed with good results on phantoms and patients. We think that it can be easily implemented for specific diagnostic problems.

  15. Patient radiation exposure in computerized tomography

    Energy Technology Data Exchange (ETDEWEB)

    Pavlov, V [Meditsinska Akademiya, Sofia (Bulgaria)

    1980-01-01

    Radiation exposure to patients undergoing axial computerized tomography as a tool of neurological X-ray diagnostics was studied. Doses thereby delivered were compared with those from routine head films at X-ray tube parameters 200 W, 70 kV, and 70 cm target-to-patient distance. Radiation exposures were analyzed with a view to improving shielding and procedural techniques. Comparisons were made using LiF TLD measurements with an Alderson phantom (standard for axial computer tomography). Skin and intracranial space doses were compared using two computers, Siretom I and Siretom 2000, for various positionings: frontal, fronto-lateral, temporal, temporo-occipital, and occipital. In addition, patient body doses with or without shielding and doses to subjects attending sick children or restless adults were examined. Achievable protection was estimated for lead shields of 0.5 mm lead equivalent. It was concluded that radiation doses delivered to neurologic patients undergoing axial computer tomography are smaller than those resulting from conventional X-ray examinations.

  16. Emission computerized-tomography and determination of local brain function

    International Nuclear Information System (INIS)

    Kuhl, D.E.; Alavi, A.; Reivich, M.; Edwards, R.Q.; Fenton, C.A.; Zimmerman, R.A.

    1975-01-01

    Methods for the three dimensional reconstruction of /sup 99m/Tc brain scans are described. The diagnostic advantages of computerized tomography in the localization of brain tumors and in measurements of local cerebral blood flow are discussed. (U.S.)

  17. Quality criteria in computerized tomography of the chest

    International Nuclear Information System (INIS)

    Doehring, W.

    1985-01-01

    The quality of thoracical computerized tomography (CT) - like any other CT examination - depends from the quality of the equipment used, from the skill of the examinor and the properties of the patient. Concerning computerized chest tomograms, rapid scan equipment should be used only and slow translation - rotation systems should not be used any more. Whereas the quality of computerized tomograms may be influenced by the patient in the scanning process only, the examining physician will decisively influence the possible informative value of the examination also in the reconstruction of the CT value matrix, in single demonstration of CT values and, possibly, in additional measurement value processing as well as in the interpretation of findings. Use of equipment should always consider the technical potential provided by the equipment to be oriented to the clinical issue, and the conditions preset by the patient. (orig.) [de

  18. Use of computerized tomography and magnetic resonance imaging

    International Nuclear Information System (INIS)

    Tjoerstad, K.

    1992-01-01

    This is a neurologist's opinion on how computerized tomography and magnetic resonance imaging have improved the doctor's diagnostic possibilities, changed patient/doctor relationship and increased the patients' expectations from diagnostic tests. How should the often conflicting interests of patients, society and doctors be handled? 15 refs., 1 fig., 1 tab

  19. Paracoccidioidomycosis: High-resolution computed tomography-pathologic correlation

    International Nuclear Information System (INIS)

    Marchiori, Edson; Valiante, Paulo Marcos; Mano, Claudia Mauro; Zanetti, Glaucia; Escuissato, Dante L.; Souza, Arthur Soares; Capone, Domenico

    2011-01-01

    Objective: The purpose of this study was to describe the high-resolution computed tomography (HRCT) features of pulmonary paracoccidioidomycosis and to correlate them with pathologic findings. Methods: The study included 23 adult patients with pulmonary paracoccidioidomycosis. All patients had undergone HRCT, and the images were retrospectively analyzed by two chest radiologists, who reached decisions by consensus. An experienced lung pathologist reviewed all pathological specimens. The HRCT findings were correlated with histopathologic data. Results: The predominant HRCT findings included areas of ground-glass opacities, nodules, interlobular septal thickening, airspace consolidation, cavitation, and fibrosis. The main pathological features consisted of alveolar and interlobular septal inflammatory infiltration, granulomas, alveolar exudate, cavitation secondary to necrosis, and fibrosis. Conclusion: Paracoccidioidomycosis can present different tomography patterns, which can involve both the interstitium and the airspace. These abnormalities can be pathologically correlated with inflammatory infiltration, granulomatous reaction, and fibrosis.

  20. Coupling two iteratives algorithms for density measurements by computerized tomography

    International Nuclear Information System (INIS)

    Silva, L.E.M.C.; Santos, C.A.C.; Borges, J.C.; Frenkel, A.D.B.; Rocha, G.M.

    1986-01-01

    This work develops a study for coupling two iteratives algotithms for density measurements by computerized tomography. Tomographies have been obtained with an automatized prototype, controled by a microcomputer, projected and assembled in the Nuclear Instrumentation Laboratory, at COPPE/UFRJ. Results show a good performance of the tomographic system, and demonstrate the validity of the method of calculus adopted. (Author) [pt

  1. Development of sealed sample containers and high resolution micro-tomography

    Energy Technology Data Exchange (ETDEWEB)

    Uesugi, Kentaro, E-mail: ueken@spring8.or.jp; Takeuchi, Akihisa; Suzuki, Yoshio [Japan synchrotron radiation research institute, JASRI/SPring-8 Kouto 1-1-1, Sayo, Hyogo 679-5198 Japan (Japan); Uesugi, Masayuki [Japan Aerospace Exploration Agency (ISAS/JAXA), Sagamihara, Kanagawa 252-5210 (Japan); Hamada, Hiroshi [NTT Advanced technology Corporation, Atsugi, Kanagawa 243-0124 (Japan)

    2016-01-28

    A sample container and a high resolution micro-tomography system have been developed at BL47XU at SPring-8. The container is made of a SiN membrane in a shape of truncated pyramid, which makes it possible to exclude oxygen and moisture in the air. The sample rotation stage for tomography is set downward to keep the sample in the container without any glue. The spatial resolution and field of view are 300 nm and 110 μm using a Fresnel zone plate objective with an outermost zone width of 100 nm at 8 keV, respectively. The scan time is about 20 minutes for 1800 projections. A 3-D image of an asteroid particle was successfully obtained without adhesive and contamination.

  2. Significance of computerized tomography and nasal cytology in the ...

    African Journals Online (AJOL)

    Ehab

    assessment of sinus disease in asthmatic children. Rhinosinusitis is a common asthma comorbidity. Nasal eosinophil or neutrophil score >0.5 provides a better predictive value for rhinosinusitis compared to total serum IgE. Keywords: computerized tomography, nasal sinus, asthma, sinusitis, allergic rhinitis, children.

  3. Computerized axial tomography : the tool in osseointegrated dental implants

    International Nuclear Information System (INIS)

    Fernandez-Lopez, Otton

    2002-01-01

    Failure rates in rehabilitations with osseointegrated implants are handled through appropriate radiographic preoperative planning. The appropriate length of the implant without running the risk of a perforation of vital structures, has been determined by a radiographic diagnosis. Computerized and conventional axial tomography have proved to be invaluable elements for pre-surgical evaluation. A radiologic guidance is elaborated to perform a computerized axial tomography (CT) of maxillary bones in totally edentulous patients. Surgical guides are constructed from a wax-up emanated from the information of the CT. The CT has proven to be an radiographic indispensable element to achieve the surgical-prosthetic success in osseointegrated dental implants. The CT has allowed the realization of a precise wax-up for making of surgical guide and a precise temporary prostheses in positioning of osseointegrated implants, with the consequent saving time and money for the rehabilitator and patient [es

  4. High-resolution PET [Positron Emission Tomography] for Medical Science Studies

    Science.gov (United States)

    Budinger, T. F.; Derenzo, S. E.; Huesman, R. H.; Jagust, W. J.; Valk, P. E.

    1989-09-01

    One of the unexpected fruits of basic physics research and the computer revolution is the noninvasive imaging power available to today's physician. Technologies that were strictly the province of research scientists only a decade or two ago now serve as the foundations for such standard diagnostic tools as x-ray computer tomography (CT), magnetic resonance imaging (MRI), magnetic resonance spectroscopy (MRS), ultrasound, single photon emission computed tomography (SPECT), and positron emission tomography (PET). Furthermore, prompted by the needs of both the practicing physician and the clinical researcher, efforts to improve these technologies continue. This booklet endeavors to describe the advantages of achieving high resolution in PET imaging.

  5. The industrial computerized tomography applied to the rock analysis

    International Nuclear Information System (INIS)

    Tetzner, Guaraciaba de Campos

    2008-01-01

    This work is a study of the possibilities of the technical applications of Computerized Tomography (CT) by using a device developed in the Radiation Technology Center (CTR), Institute for Energy and Nuclear Research (IPEN-CNEN/SP). The equipment consists of a gamma radiation source ( 60 Co), a scintillation detector of sodium iodide doped with thallium (NaI (Tl)), a mechanical system to move the object (rotation and translation) and a computer system. This operating system has been designed and developed by the CTR-IPEN-CNEN/SP team using national resources and technology. The first validation test of the equipment was carried out using a cylindrical sample of polypropylene (phantom) with two cylindrical cavities (holes) of 5 x 25 cm (diameter and length). In these tests, the holes were filled with materials of different density (air, oil and metal), whose attenuation coefficients are well known. The goal of this first test was to assess the response quality of the equipment. The present report is a study comparing computerized tomography equipment CTR-IPEN-CNEN/SP which uses a source of gamma radiation ( 60 Co) and other equipment provided by the Department of Geosciences in the University of Texas (CTUT), which uses an X-ray source (450 kV and 3.2 mA). As a result, the images obtained and the comprehensive study of the usefulness of the equipment developed here strengthened the proposition that the development of industrial computerized tomography is an important step toward consolidating the national technology. (author)

  6. Computerized tomography in diffuse diseases of the liver. Pt. 2

    International Nuclear Information System (INIS)

    Helmberger, H.; Vogel, U.; Bautz, W.

    1993-01-01

    Computerized tomography is a first-line method of imaging to confirm diffuse disorders of the liver suggested by preliminary clinical and biochemical findings. If the disease is caused by an obstructed vessel, this is reliably detected. For most types of thesaurismosis as well as hepatic steatosis and cirrhosis of the liver approaches to quantitative determinations of the spread of disease have been described in theory but so far failed to show great merits in practice. The transition from hepatic fibrosis to cirrhosis as the final developmental stage common to all those disorders has typical features on computerized tomography. This explains why the use of this method in diffuse hepatic disease offers particular advantages as regards the detection of complications occurring at an advanced stage ot the diagnosis of changes developing into malignancies. (orig.) [de

  7. Increased intracranial pressure: evaluation by computerized tomography

    International Nuclear Information System (INIS)

    Lightfoote, W.E.; Pressman, B.D.

    1975-01-01

    Computerized tomography is clearly very useful in the evaluation of patients with increased intracranial pressure and suspected pseudotumor cerebri. It provides an index of ventricular size and configuration and has the capability of demonstrating intracranial lesions. Moreover, this new technique is rapid and non-invasive, and is without attendant risks. Examinations may be performed serially as the clinical process evolves, thereby giving roentgenographic correlation to the clinical features. (U.S.)

  8. Contribution of computerized tomography to orbit fracture diagnosis

    International Nuclear Information System (INIS)

    Nemeth, T.; Sobota, J.

    1984-01-01

    Suitability and specificity of examinations using computerized tomography are discussed for diagnoses fractures of the orbit including accurate anatomical localization of traumatic changes. The possibility of accurate assessment of the drop of the floor of the orbit which is essential for determination of the thickness of the bone or cartilaginous graft under the eyeball is also important

  9. Organ doses from computerized tomography examinations

    Energy Technology Data Exchange (ETDEWEB)

    Janeczek, J.

    1995-12-31

    Estimates of mean organs doses from five typical computerized tomography (CT) examinations were obtained. Measurements were done using Rando-Alderson anthropomorphic phantom and thermoluminescent dosemeters (TLD). Radiation dose distributions within a phantom has been measured for each examination and results were used for organ dose calculation. Doses to organs specified by ICPR 60 Recommendations were measured for five CT scanners (CT/T8800, CT 9800, CT MAX - made by General Electric; CT 1200 SX - made by Picker; SOMATOM 2 - made by Siemens). Dose distributions from scattered radiation were measured and indicate that scattered radiation dose to thyroid and eye lens can be reduced by proper examination limits setting. The lowest mean organ doses were obtained from CT/T8800 scanner. More advanced scanners using high intensity continuous radiation were giving higher organ doses. (author). 23 refs, 6 figs, 13 tabs.

  10. Organ doses from computerized tomography examinations

    International Nuclear Information System (INIS)

    Janeczek, J.

    1995-01-01

    Estimates of mean organs doses from five typical computerized tomography (CT) examinations were obtained. Measurements were done using Rando-Alderson anthropomorphic phantom and thermoluminescent dosemeters (TLD). Radiation dose distributions within a phantom has been measured for each examination and results were used for organ dose calculation. Doses to organs specified by ICPR 60 Recommendations were measured for five CT scanners (CT/T8800, CT 9800, CT MAX - made by General Electric; CT 1200 SX - made by Picker; SOMATOM 2 - made by Siemens). Dose distributions from scattered radiation were measured and indicate that scattered radiation dose to thyroid and eye lens can be reduced by proper examination limits setting. The lowest mean organ doses were obtained from CT/T8800 scanner. More advanced scanners using high intensity continuous radiation were giving higher organ doses. (author). 23 refs, 6 figs, 13 tabs

  11. Computerized tomography of orbital lesions

    International Nuclear Information System (INIS)

    Kuroiwa, Mayumi

    1981-01-01

    Two different types of computerized tomography scanners (CT scanner), i.e. a whole-body CT scanner (GE-CT/T8800) and a cerebral CT scanner (EMI-1010), were compared in the assessment and diagnosis of various orbital lesions. The whole-body CT scanner was found to be advantageous over the cerebral CT scanner for the following reasons: (1) CT images were more informative due to thinner slices associated with smaller-sized and larger-numbered matrices; (2) less artifacts derived from motion of the head or eyeball were produced because of the shorter scanning time; (3) with a devised gantry, coronal dissections were available whenever demanded. (author)

  12. Pneumocystis carinii pneumonia in acquired immunodeficiency syndrome - correlation of high-resolution computed tomography and anatomopathology

    International Nuclear Information System (INIS)

    Marchiori, Edson; Moreira, Luiza Beatriz; Capone, Domenico; Moraes, Heleno Pinto de; Pereira, Cyntia Inez Guedes Soares

    2001-01-01

    We present the main findings observed on the high-resolution computed tomography examinations of 15 patients with acquired immunodeficiency syndrome and Pneumocystis carinii pneumonia. The high-resolution computed tomography and autopsy findings of 5 patients were also compared. The most frequently observed high-resolution computed tomography patterns were ground-glass attenuation, consolidation areas, crazy-paving pattern and cysts. Nodules and intralobular reticulation were less frequently observed. Ground-glass attenuation and consolidation areas corresponded to alveolar filling with inflammatory exudate. Thickening of the interlobular septa was due to cell infiltration and edema. One patient presented interlobular reticulation, and the pathology study revealed alveolar septa thickening due to cell infiltration and fibrosis. Nodules observed in one of the patients corresponded to a patchy intra alveolar accumulation of microorganisms and inflammatory cells forming a 'granulomatous' pattern. (author)

  13. Assessment of computerized tomography devices in Minas Gerais state, Brazil

    International Nuclear Information System (INIS)

    Oliveira, Paulo Marcio C.; Horta, Mara Alice Avelar Saraiva; Santana, Priscila do Carmo; Magalhaes, Marcos Juliano

    2011-01-01

    Computed Tomography (CT) is the diagnostic imaging method most commonly performed today. It is a device that is undergoing a technological evolution and their quality control is sorely needed. The image quality evaluation process allow a better diagnosis and control of the patient dose received during image acquisition. The CT doses are higher than other X-ray examination techniques, like a conventional X-ray. Performance evaluation of computed tomography in Minas Gerais is not significant. Therefore, this work aims to analyze 20 CT equipment in Minas Gerais, with parameters according to the national regulatory agency (ANVISA - Agencia Nacional de Vigilancia Sanitaria) in twelve quality control tests. Sixty five percent (65%) of CT equipment evaluated showed excellent results and were not disapproved in any of the tests performed and 30% had failed in only one of the twelve tests performed. The worst result was found in the CT scanners in the test that evaluates the low contrast resolution, where 20% of CT showed non-compliance, followed by the test that evaluates the x-rays collimation beam, where 15% had failed. The tests allowed us to observe that the twenty computerized tomography equipment achieved a great pass rate. Considering that the evaluated CTs performed the quality control tests for the first time, it is concluded that the equipment used in clinics and hospitals are of good quality image and low radiation doses. (author)

  14. Breaking the Crowther limit: Combining depth-sectioning and tilt tomography for high-resolution, wide-field 3D reconstructions

    International Nuclear Information System (INIS)

    Hovden, Robert; Ercius, Peter; Jiang, Yi; Wang, Deli; Yu, Yingchao; Abruña, Héctor D.; Elser, Veit; Muller, David A.

    2014-01-01

    To date, high-resolution ( 6 nm) to appear blurred or missing. Here we demonstrate a three-dimensional imaging method that overcomes both these limits by combining through-focal depth sectioning and traditional tilt-series tomography to reconstruct extended objects, with high-resolution, in all three dimensions. The large convergence angle in aberration corrected instruments now becomes a benefit and not a hindrance to higher quality reconstructions. A through-focal reconstruction over a 390 nm 3D carbon support containing over 100 dealloyed and nanoporous PtCu catalyst particles revealed with sub-nanometer detail the extensive and connected interior pore structure that is created by the dealloying instability. - Highlights: • Develop tomography technique for high-resolution and large field of view. • We combine depth sectioning with traditional tilt tomography. • Through-focal tomography reduces tilts and improves resolution. • Through-focal tomography overcomes the fundamental Crowther limit. • Aberration-corrected becomes a benefit and not a hindrance for tomography

  15. Computerized tomography and its diagnostic value in the imaging of limbs

    International Nuclear Information System (INIS)

    Myllylae, V.; Tervonen, O.; Paeivaensalo, M.; Jalovaara, P.; Merikanto, J.; Maekaeraeinen, H.; Oulu Univ.

    1987-01-01

    The application of computerized tomography in skeletal diagnostics has many advantages over plain film radiography. Its use as a supplementary technique in traumatology and oncology is strongly advised. (orig.) [de

  16. A case of multiple intracranial tuberculoma followed by serial computerized tomography

    International Nuclear Information System (INIS)

    Kummer, R. von; Storch, B.; Krause, K.H.; Rauch, H.

    1981-01-01

    This is the case report of an Indian living in Europe who suffered from multiple cerebral tuberculomes in connexion with extrapulmonal tuberculosis. The retrogression of the inflammatory granulomes and the surrounding cerebral edema by treatment with tuberculostatics and Dexamethasone was observed by means of computerized tomography (CT) over a period of 8 months. The value of CT in the diagnosis and treatment of cerebral tuberculomes is discussed. The diagnosis of cerebral tuberculomes is difficult as neither the clinical picture nor additional neuroradiological tests ensure safe delimitation against other intracranial growths. In how far this situation has changed by the introduction of CT into diagnostics is discussed by the example of serial computerized tomography on a patient with multiple cerebral tuberculomes. (orig.) [de

  17. High-resolution multimodal clinical multiphoton tomography of skin

    Science.gov (United States)

    König, Karsten

    2011-03-01

    This review focuses on multimodal multiphoton tomography based on near infrared femtosecond lasers. Clinical multiphoton tomographs for 3D high-resolution in vivo imaging have been placed into the market several years ago. The second generation of this Prism-Award winning High-Tech skin imaging tool (MPTflex) was introduced in 2010. The same year, the world's first clinical CARS studies have been performed with a hybrid multimodal multiphoton tomograph. In particular, non-fluorescent lipids and water as well as mitochondrial fluorescent NAD(P)H, fluorescent elastin, keratin, and melanin as well as SHG-active collagen has been imaged with submicron resolution in patients suffering from psoriasis. Further multimodal approaches include the combination of multiphoton tomographs with low-resolution wide-field systems such as ultrasound, optoacoustical, OCT, and dermoscopy systems. Multiphoton tomographs are currently employed in Australia, Japan, the US, and in several European countries for early diagnosis of skin cancer, optimization of treatment strategies, and cosmetic research including long-term testing of sunscreen nanoparticles as well as anti-aging products.

  18. High-resolution retinal imaging using adaptive optics and Fourier-domain optical coherence tomography

    Science.gov (United States)

    Olivier, Scot S.; Werner, John S.; Zawadzki, Robert J.; Laut, Sophie P.; Jones, Steven M.

    2010-09-07

    This invention permits retinal images to be acquired at high speed and with unprecedented resolution in three dimensions (4.times.4.times.6 .mu.m). The instrument achieves high lateral resolution by using adaptive optics to correct optical aberrations of the human eye in real time. High axial resolution and high speed are made possible by the use of Fourier-domain optical coherence tomography. Using this system, we have demonstrated the ability to image microscopic blood vessels and the cone photoreceptor mosaic.

  19. Status of routine post-mortem computerized tomography in Odense, Denmark

    DEFF Research Database (Denmark)

    Leth, Peter Mygind

    2008-01-01

    rarely is a substitute for autopsy, but may contribute with important new information in many cases such as identifications (including mass-disasters), battered child, gunshot wounds, traffic accidents and air embolism. Computerized tomography provides documentation in digital form - easily stored...

  20. Breaking the Crowther limit: Combining depth-sectioning and tilt tomography for high-resolution, wide-field 3D reconstructions

    Energy Technology Data Exchange (ETDEWEB)

    Hovden, Robert, E-mail: rmh244@cornell.edu [School of Applied and Engineering Physics and Kavli Institute at Cornell for Nanoscale Science, Cornell University, Ithaca, NY 14853 (United States); Ercius, Peter [National Center for Electron Microscopy, Lawrence Berkeley National Laboratory, Berkeley, CA 94720 (United States); Jiang, Yi [Department of Physics, Cornell University, Ithaca, NY 14853 (United States); Wang, Deli; Yu, Yingchao; Abruña, Héctor D. [Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853 (United States); Elser, Veit [Department of Physics, Cornell University, Ithaca, NY 14853 (United States); Muller, David A. [School of Applied and Engineering Physics and Kavli Institute at Cornell for Nanoscale Science, Cornell University, Ithaca, NY 14853 (United States)

    2014-05-01

    To date, high-resolution (<1 nm) imaging of extended objects in three-dimensions (3D) has not been possible. A restriction known as the Crowther criterion forces a tradeoff between object size and resolution for 3D reconstructions by tomography. Further, the sub-Angstrom resolution of aberration-corrected electron microscopes is accompanied by a greatly diminished depth of field, causing regions of larger specimens (>6 nm) to appear blurred or missing. Here we demonstrate a three-dimensional imaging method that overcomes both these limits by combining through-focal depth sectioning and traditional tilt-series tomography to reconstruct extended objects, with high-resolution, in all three dimensions. The large convergence angle in aberration corrected instruments now becomes a benefit and not a hindrance to higher quality reconstructions. A through-focal reconstruction over a 390 nm 3D carbon support containing over 100 dealloyed and nanoporous PtCu catalyst particles revealed with sub-nanometer detail the extensive and connected interior pore structure that is created by the dealloying instability. - Highlights: • Develop tomography technique for high-resolution and large field of view. • We combine depth sectioning with traditional tilt tomography. • Through-focal tomography reduces tilts and improves resolution. • Through-focal tomography overcomes the fundamental Crowther limit. • Aberration-corrected becomes a benefit and not a hindrance for tomography.

  1. Computerized tomography of the mandibular joints and masticatory muscles

    International Nuclear Information System (INIS)

    Huels, A.B.

    1981-01-01

    A methodology for computerized tomography of the mandibular joints was developed and applied in 80 test persons. Imaging of the mandibular joints is possible with a tomographic technique with 5 mm-overlap, full utilisation of the enlargement capacity of the imaging device, and combined use of transversal and coronary tomography. The method yields full latero-medial, cranio-caudal and anterior-posterior views of the condyle and fossa contours, free of interferences and of distortions caused by the projection. Positional diagnoses are thus possible as well as diagnoses of pathological structural changes. (orig./MG) [de

  2. Prognosis of the computerized tomography in the severe head injury

    International Nuclear Information System (INIS)

    Garcia-Nieto, J.J.; Lorenzo Dominguez, M.T.; Martin Sanchez, M.J.; Sanchez Gonzalez, E.

    1991-01-01

    A prospective study is made with sixty five people affected of severe head injury, that is to say, with eight or less points in the Glasgow Coma Scale (GCS), when they get to the hospital. They are studied by computerized tomography at the income, but also, three and seven days after arriving. In this way, we appraise the type of the lesion the intensity and the possible effect-wass, considering in the last case, three features: a) ventricular collapse; b) the mean line structure s shift; c) perimesencefalic cisterns affectation. The findings of this study, are parametized and we were able to introduce them into a computer, getting. The relations between these findings ands the end-results. These last ones appraised throungh the Glasgow Outcome Scale (GOS). We could confirm, that certain findings in the computerized tomography have and unavoidable prognosis, where as others have a better prognosis. (Author)

  3. Clinical use of pulmonary function tests and high-resolution tomography in interstitial lung diseases

    International Nuclear Information System (INIS)

    Garcia C, Clara P; Mejia M, Luis F

    2010-01-01

    Diagnosis of interstitial lung diseases is generally arrived at by clinical history, physical examination, and radiologic images, especially high-resolution CT-scanning. It is important to note that, while these diseases have different clinical and histological characteristics, they share a basic pattern of abnormal lung function. With regard to high-resolution tomography, the characteristics of these diseases are similar, although there are specific differences that can be helpful for correct diagnosis. These diseases have severe consequences on respiratory gas exchange. These alterations, combined with other abnormalities of lung function, cause the signs and symptoms and have an impact on quality of life. The use of physiologic parameters is not only helpful for diagnosis, but can also assess severity, help to define the consequences of treatment, and aid in the follow-up. Although some pulmonary function tests can remain completely normal with severe radiographic findings, 10% of patients have impaired lung function before radiologic changes. High-resolution tomography is an essential imaging tool for the study of these patients. This is true not only for diagnosis, but also with regard to clinical parameters and follow-up. Its prognostic use is continually gaining importance. In this article we assess the clinical use of pulmonary function tests and high-resolution tomography in interstitial lung diseases.

  4. Dosimetry of computerized tomography in the evaluation of hip dysplasia

    Energy Technology Data Exchange (ETDEWEB)

    Guyer, B.; Bassano, D.A.; Levinsohn, E.M.; Smith, D.S.; Cady, R.B.

    1984-07-01

    The usefulness of computerized tomography (CT) in the assessment of hip dysplasia has recently been given attention in the literature and concern regarding radiation dose has been raised. This study was undertaken to measure the radiation dose, both in and out of plaster, for plain films, arthrography, tomography, and CT. A method is suggested to reduce dosage by 80% without compromising diagnostic information. Our experience with 25 scans of patients aged 4 months to 39 years is presented.

  5. Refinement procedure for the image alignment in high-resolution electron tomography.

    Science.gov (United States)

    Houben, L; Bar Sadan, M

    2011-01-01

    High-resolution electron tomography from a tilt series of transmission electron microscopy images requires an accurate image alignment procedure in order to maximise the resolution of the tomogram. This is the case in particular for ultra-high resolution where even very small misalignments between individual images can dramatically reduce the fidelity of the resultant reconstruction. A tomographic-reconstruction based and marker-free method is proposed, which uses an iterative optimisation of the tomogram resolution. The method utilises a search algorithm that maximises the contrast in tomogram sub-volumes. Unlike conventional cross-correlation analysis it provides the required correlation over a large tilt angle separation and guarantees a consistent alignment of images for the full range of object tilt angles. An assessment based on experimental reconstructions shows that the marker-free procedure is competitive to the reference of marker-based procedures at lower resolution and yields sub-pixel accuracy even for simulated high-resolution data. Copyright © 2011 Elsevier B.V. All rights reserved.

  6. Accurately Diagnosing Uric Acid Stones from Conventional Computerized Tomography Imaging: Development and Preliminary Assessment of a Pixel Mapping Software.

    Science.gov (United States)

    Ganesan, Vishnu; De, Shubha; Shkumat, Nicholas; Marchini, Giovanni; Monga, Manoj

    2018-02-01

    Preoperative determination of uric acid stones from computerized tomography imaging would be of tremendous clinical use. We sought to design a software algorithm that could apply data from noncontrast computerized tomography to predict the presence of uric acid stones. Patients with pure uric acid and calcium oxalate stones were identified from our stone registry. Only stones greater than 4 mm which were clearly traceable from initial computerized tomography to final composition were included in analysis. A semiautomated computer algorithm was used to process image data. Average and maximum HU, eccentricity (deviation from a circle) and kurtosis (peakedness vs flatness) were automatically generated. These parameters were examined in several mathematical models to predict the presence of uric acid stones. A total of 100 patients, of whom 52 had calcium oxalate and 48 had uric acid stones, were included in the final analysis. Uric acid stones were significantly larger (12.2 vs 9.0 mm, p = 0.03) but calcium oxalate stones had higher mean attenuation (457 vs 315 HU, p = 0.001) and maximum attenuation (918 vs 553 HU, p uric acid stones. A combination of stone size, attenuation intensity and attenuation pattern from conventional computerized tomography can distinguish uric acid stones from calcium oxalate stones with high sensitivity and specificity. Copyright © 2018 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

  7. Pulmonary malaria: high-resolution computed tomography findings - a case report

    International Nuclear Information System (INIS)

    Rodrigues, Rosana; Souza, Daniel Andrade Tinoco de; Marchiori, Edson

    2004-01-01

    We report the case of a 38-year-old man with pulmonary malaria. High-resolution computed tomography showed thickening of the peribronchovascular interstitium and interlobular septa, areas of consolidation and ground glass attenuation and bilateral pleural effusion suggesting pulmonary edema. The patient recovered well after receiving specific treatment and was discharged after 11 days of hospitalization. (author)

  8. Computerized tomography of the vertebral column following traumatic lesion

    International Nuclear Information System (INIS)

    Taenzer, B.; Gmelin, E.; Burmester, E.; Babaian, E.; Weiss, H.D.; Hohlbach, G.

    1984-01-01

    In 58 patients with lesions of the vertebral column in the thoracal and lumbar section established by conventional X-ray, the informative power of computerized tomography was tested. Axial projection with the superimposition-free presentation of bone and soft-tissue structures in the motional segment clears up the diagnostically decisive question of the extent of the lesion and form of fracture, and thus provides information on the stability or instability of the fracture relevant for the therapeutic action taken. All patients had compression fractures of vertebrae, with a fragment of the front edge broken away in 50 cases and one of the back edge broken away in 17 cases. In 30 cases the intervertebral disks were damaged. 43 fractures were stable, 25 were unstable. The instability of 13 fractures was only recognized by CT. In essence, the diagnostic action to be taken begins with a grand-survey X-ray in two planes as a screening, with computerized tomography following in the positive case. Conventional tomograms are not necessary. (BWU) [de

  9. Diagnosis of cholesteatoma by high resolution computed tomography

    International Nuclear Information System (INIS)

    Kakitsubata, Yousuke; Kakitsubata, Sachiko; Ogata, Noboru; Asada, Keiko; Watanabe, Katsushi; Tohno, Tetsuya; Makino, Kohji

    1988-01-01

    Three normal volunteers and 57 patients with cholesteatoma were examined by high resolution computed tomography. Serial sections were made through the temporal bone at the nasaly inclined position of 30 degree to the orbitomeatal line (semiaxial plane ; SAP). The findings of temporal bone structures in normal subjects were evaluated in SAP and axial plane (OM). Although the both planes showed good visualization, SAP showed both the eustachian tube and tympanic cavity in one slice. In cholesteatoma soft tissue masses in the tympanic cavity, mastoid air cells and Eustachian tube were demonstrated clearly by SAP. (author)

  10. Bronchiolitis obliterans following exposure to sulfur mustard: chest high resolution computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    Ghanei, Mostafa E-mail: m.ghanei@bmsu.ac.ir; Mokhtari, Majid; Mohammad, Mehdi Mir; Aslani, Jafar

    2004-11-01

    Background: Pulmonary complications are known to occur in over half of the patients exposed to sulfur mustard (SM). Chemical weapons of mass destruction (WMD) including SM were used by Iraq during Iran-Iraq war between 1983 and 1989. We undertook this study to evaluate the chest high resolution computerized tomography (HRCT) as a diagnostic tool in patients with documented exposure to SM and chronic respiratory symptoms. Method: The medical records of 155 patients exposed to SM during Iran-Iraq war and suffered respiratory complications were reviewed. Chest HRCTs of these patients were examined. Ten healthy controls with no history of exposure to HD were matched for age, gender, and chest HRCT protocol applied. Results: Fifty chest HRCTs of these patients were randomly selected for this study. The most frequent findings were; air trapping 38 (76%), bronchiectasis 37 (74%), mosaic parenchymal attenuation (MPA) 36 (72%), irregular and dilated major airways 33 (66%) bronchial wall thickening (BWT) 45 (90%), and interlobular septal wall thickening (SWT) 13 (26%), respectively. Air trapping in one patient (10%) was the only positive finding in the control group. Conclusions: Chest HRCT findings of bronchiectasis, air trapping, MPA, SWT, and BWT were seen in our patients 15 years after exposure to HD. These findings suggest the diagnosis of bronchiolitis obliterans (BO). We did not encounter chest HRCT features consistent with pulmonary fibrosis.

  11. Anatomic radiological study of transverse diameter of abdominal aorta by computerized tomography

    International Nuclear Information System (INIS)

    Ures, S.

    1984-01-01

    The transverse diameter of abdominal aorta by computerized tomography is studied. The purpose is establish the frequent standard diameters and then diagnose early pathologies, mainly aneurisms. (M.A.C.) [pt

  12. The diagnostic value of cranial computerized tomography in exogenous psychoses and mental disorders associated with organic diseases

    International Nuclear Information System (INIS)

    Strobl, G.; Reisner, Th.; Zeiler, K.; Vienna Univ.

    1980-01-01

    205 patients hospitalized in a psychiatric department were subjected to cranial computerized tomography. The diagnosis on discharge according to the ICD key in each case was ''psychoses or mental disorders associated with physical conditions''. Pathological findings were obtained in 67.8% of the patients. In the case of space-occupying lesions the connection between psychiatric symptoms and syndromes and the underlying organic disease is obvious. Moreover, with inflammatory, vascular or traumatic diseases, a relationship to focal lesions found on the computer tomography appears likely if backed by appropriate neurological indications in the history or an clinical examinations. However, when alterations signifying diffuse brain atrophy are obtained on computer tomography any connections with psychiatric features should be very critically evaluated and, in individual cases, such connections had better not be looked for at all. Especially in cases of psychoses or mental disorders associated with physical conditions cranial computerized tomography is of high diagnostic value and the indications for its implementation in these cases should be judged very leniently. (author)

  13. High resolution IVEM tomography of biological specimens

    Energy Technology Data Exchange (ETDEWEB)

    Sedat, J.W.; Agard, D.A. [Univ. of California, San Francisco, CA (United States)

    1997-02-01

    Electron tomography is a powerful tool for elucidating the three-dimensional architecture of large biological complexes and subcellular organelles. The introduction of intermediate voltage electron microscopes further extended the technique by providing the means to examine very large and non-symmetrical subcellular organelles, at resolutions beyond what would be possible using light microscopy. Recent studies using electron tomography on a variety of cellular organelles and assemblies such as centrosomes, kinetochores, and chromatin have clearly demonstrated the power of this technique for obtaining 3D structural information on non-symmetric cell components. When combined with biochemical and molecular observations, these 3D reconstructions have provided significant new insights into biological function.

  14. Aspects of pulmonary histiocytosis X on high resolution computed tomography

    International Nuclear Information System (INIS)

    Costa, N.S.S.; Castro Lessa Angela, M.T. de; Angelo Junior, J.R.L.; Silva, F.M.D.; Kavakama, J.; Carvalho, C.R.R. de; Cerri, G.G.

    1995-01-01

    Pulmonary histiocytosis X is a disease that occurs in young adults and presents with nodules and cysts, mainly in upper lobes, with consequent pulmonary fibrosis. These pulmonary changes are virtually pathognomonic findings on high resolution computed tomography, that allows estimate the area of the lung involved and distinguish histiocytosis X from other disorders that also produces nodules and cysts. (author). 10 refs, 2 tabs, 6 figs

  15. COST EFFECTIVE AND HIGH RESOLUTION SUBSURFACE CHARACTERIZATION USING HYDRAULIC TOMOGRAPHY

    Science.gov (United States)

    2017-08-01

    objective of this project is to provide the DoD and its remediation contractors with the HT technology for delineating the spatial distribution of...STATEMENT Approved for public release; distribution is unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT Hydraulic Tomography ( HT ) is a high-resolution...performance of subsurface remedial actions at environmental sites. The good technical performance and cost-effectiveness of HT have been demonstrated in

  16. Radiation exposure of the gonads in infant brain computerized tomography

    International Nuclear Information System (INIS)

    Berndt, L.; Rosenkranz, G.; Tellkamp, H.

    1988-01-01

    In 61 babies and infants the gonadal dose due to brain computerized tomography was determined over the symphysis by thermoluminescent dosimetry. The average radiation dose was 43 mGy corresponding with data reported. Shielding of the testes in infants is an additional burden and worth discussing because of the low absolute gonadal dose

  17. High resolution computed tomography of positron emitters

    International Nuclear Information System (INIS)

    Derenzo, S.E.; Budinger, T.F.; Cahoon, J.L.; Huesman, R.H.; Jackson, H.G.

    1976-10-01

    High resolution computed transaxial radionuclide tomography has been performed on phantoms containing positron-emitting isotopes. The imaging system consisted of two opposing groups of eight NaI(Tl) crystals 8 mm x 30 mm x 50 mm deep and the phantoms were rotated to measure coincident events along 8960 projection integrals as they would be measured by a 280-crystal ring system now under construction. The spatial resolution in the reconstructed images is 7.5 mm FWHM at the center of the ring and approximately 11 mm FWHM at a radius of 10 cm. We present measurements of imaging and background rates under various operating conditions. Based on these measurements, the full 280-crystal system will image 10,000 events per sec with 400 μCi in a section 1 cm thick and 20 cm in diameter. We show that 1.5 million events are sufficient to reliably image 3.5-mm hot spots with 14-mm center-to-center spacing and isolated 9-mm diameter cold spots in phantoms 15 to 20 cm in diameter

  18. Accelerated high-resolution photoacoustic tomography via compressed sensing

    Science.gov (United States)

    Arridge, Simon; Beard, Paul; Betcke, Marta; Cox, Ben; Huynh, Nam; Lucka, Felix; Ogunlade, Olumide; Zhang, Edward

    2016-12-01

    Current 3D photoacoustic tomography (PAT) systems offer either high image quality or high frame rates but are not able to deliver high spatial and temporal resolution simultaneously, which limits their ability to image dynamic processes in living tissue (4D PAT). A particular example is the planar Fabry-Pérot (FP) photoacoustic scanner, which yields high-resolution 3D images but takes several minutes to sequentially map the incident photoacoustic field on the 2D sensor plane, point-by-point. However, as the spatio-temporal complexity of many absorbing tissue structures is rather low, the data recorded in such a conventional, regularly sampled fashion is often highly redundant. We demonstrate that combining model-based, variational image reconstruction methods using spatial sparsity constraints with the development of novel PAT acquisition systems capable of sub-sampling the acoustic wave field can dramatically increase the acquisition speed while maintaining a good spatial resolution: first, we describe and model two general spatial sub-sampling schemes. Then, we discuss how to implement them using the FP interferometer and demonstrate the potential of these novel compressed sensing PAT devices through simulated data from a realistic numerical phantom and through measured data from a dynamic experimental phantom as well as from in vivo experiments. Our results show that images with good spatial resolution and contrast can be obtained from highly sub-sampled PAT data if variational image reconstruction techniques that describe the tissues structures with suitable sparsity-constraints are used. In particular, we examine the use of total variation (TV) regularization enhanced by Bregman iterations. These novel reconstruction strategies offer new opportunities to dramatically increase the acquisition speed of photoacoustic scanners that employ point-by-point sequential scanning as well as reducing the channel count of parallelized schemes that use detector arrays.

  19. Dose evaluation in diagnostic for computerized tomography

    International Nuclear Information System (INIS)

    Flores, W.; Borges, J.C.; Mota, H.

    1998-01-01

    The patients which are subjected to computerized tomography tests are exposed to relatively high doses given as result doses on organs that are not matter to test. It was realized a dose levels raising in patients subjected to tests by T C, utilizing to measure this magnitude, TLD-100 thermoluminescent dosemeters which were put directly on the patient, in eye regions, thyroid, breast and navel; founding doses fluctuating between 29.10-49.39 mGy in organs examined and dose values between 0.21-29.10 mGy for organs that no matter to test. The applications of ionizing radiations in medicine do not have dose limits, but paying attention to the radiological protection optimization principle, it is recommended the use of clothes to anti-rays protection for zones not examined, getting with this to reduce the level doses as low as possible, without this to diminish the test quality. (Author)

  20. Pulmonary leukemic involvement: high-resolution computed tomography evaluation

    International Nuclear Information System (INIS)

    Oliveira, Ana Paola de; Marchiori, Edson; Souza Junior, Arthur Soares

    2004-01-01

    Objective: To evaluate the role of high-resolution computed tomography (HRCT) in patients with leukemia and pulmonary symptoms, to establish the main patterns and to correlate them with the etiology. Materials and Methods: This is a retrospective study of the HRCT of 15 patients with leukemia and pulmonary symptoms. The examinations were performed using a spatial high-resolution protocol and were analyzed by two independent radiologists. Results: The main HRCT patterns found were ground-glass opacity (n=11), consolidation (n=9), airspace nodules (n=3), septal thickening (n=3), tree-in-bud pattern (n=3), and pleural effusion (n=3). Pulmonary infection was the most common finding seen in 12 patients: bacterial pneumonia (n=6), fungal infection (n = 4), pulmonary tuberculosis (n=1) and viral infection (n=1). Leukemic pleural infiltration (n=1), lymphoma (n=1) and pulmonary hemorrhage (n=1) were detected in the other three patients. Conclusion: HRCT is an important tool that may suggest the cause of lung involvement, its extension and in some cases to guide invasive procedures in patients with leukemia. (author)

  1. Regional aspects of cerebral cysticercosis. Incidence and evaluation by computerized tomography in 1000 consecutive studies

    Energy Technology Data Exchange (ETDEWEB)

    Jozzolino, D.A. (Instituto de Tomografia Axial Computadorizada de Londrina (Brazil))

    One thousand consecutive studies of the entire brain were performed and 122 patients with tomographic diagnosis of cysticercosis were found. The high incidence of this disease is discussed and its endemic characteristics as well. Various forms and types are described, the most frequent being the presence of calcifications; other tests performed at the time of computerized tomography are mentioned.

  2. Radiation conditions for computerized tomography: determination and comparison

    International Nuclear Information System (INIS)

    Andrade, Lucio das Chagas de

    2016-01-01

    Radiology is the practice in which radiation beams, usually radiation X are used to produce an image of the human body in order to obtain a diagnosis, for example, to evaluate a pathological condition by computerized tomography (CT). Although the computerized tomography diagnostic potential is unquestionable, caution must be taken because the doses are almost always higher than the observed in conventional radiology procedures. The ionization chamber used for dosimetry in CT is a unsealed cylindrical chamber with 10 cm and 15 cm of sensitive length. A typical characteristics of this camera is its uniform response to radiation incident at all angles around its axis. The revised edition of IEC 61267 (2005) brought as an innovation the radiation conditions for computed tomography, RQT, that simulate non-attenuated beam and are used in special CT applications. This study aims to establish the necessary conditions to obtain radiation pattern beam computed tomography, RQT, and a calibration laboratory implementation for pencil ionization chambers used in the beam dosimetry produced by these scanners in the Metrology National Laboratory of Ionizing Radiation (LNMRI). In the implementation of RQT conditions we were found that the ratio of kerma rates in the air, with or without additional filtration equivalent to the first HVL (half-value layer), are in accordance with IEC 61267 (2005), which provides a range between 48.5% and 51.5% for each quality. The LNMRI characterized the radiation conditions of RQT series (IEC, 2005), obtaining a percentage of 49.6% for the RQT 8, 50% for the RQT 9 and 50,4% for the RQT 10. With the substitution of the total additional filtration RQT qualities, composed by Al + Cu and by a total filtration composed by copper (Cu) only, it can be seen the emergence of a similar RQT quality named Quality Copper Tomography - QCT. The results of the calibration, the RQT and QCT qualities, had expanded uncertainties with a confidence level 95.45%, less

  3. Positron emission computerized tomography: a potential tool for in vivo quantitation of the distribution of radiopharmaceuticals

    International Nuclear Information System (INIS)

    Huebner, K.F.; King, P.; Gibbs, W.D.; Washburn, L.C.; Hayes, R.L.

    1981-01-01

    The principles and some of the difficulties in quantitative positron emission computerized tomography have been discussed. We have shown that randoms and scattered events are a major cause of noise and counting errors in positron emission computerized tomography. The noise has been identified as a convoluting process and a mathematical solution has been presented. Examples of phantom studies and in vivo measurements have demonstrated that the distribution of positron emitting radiopharmaceuticals can be quantitated with much improved accuracy using the deconvolution equation to remove undesired noise

  4. High resolution X-ray tomography for stationary multiphase flows

    International Nuclear Information System (INIS)

    Schmitz, D.; Reinecke, N.; Petritsch, G.; Mewes, D.

    1998-01-01

    The high resolution which can be obtained by computer assisted tomography is used to investigate the liquid distribution and void fraction in random and structured packing. With a spatial resolution of 0.4x0.4mm 2 it is possible even to detect thin liquid films on structured packings. The experimental set-up consists of a custom-built second generation tomograph. The imaged object consists of a column filled with either a random ceramic packing of spheres or a structured metal packing. The liquid and void fraction distribution in random and structured packings with a quiescent gaseous phase is visualized. The water/air system is used. The liquid distributor consists of a perforated plate. The experimental hold-up values averaged over the column cross-section are in good agreement with empirical equations. (author)

  5. Analysis of concrete material through gamma ray computerized tomography

    International Nuclear Information System (INIS)

    Oliveira Junior, J.M. de

    2004-01-01

    Computerized Tomography (CT) refers to the cross sectional imaging of an object from both transmission or reflection data collected by illuminating the object from many different directions. The most important contribution of CT is to greatly improve abilities to distinguish regions with different gamma ray transmittance and to separate over-lying structures. The mathematical problem of the CT imaging is that of estimating an image from its projections. These projections can represent, for example, the linear attenuation coefficient of γ-rays along the path of the ray. In this work we will present some new results obtained by using tomographic techniques to analyze column samples of concrete to check the distribution of various materials and structural problems. These concrete samples were made using different proportions of stone, sand and cement. Another set of samples with different proportions of sand and cement were also used to verify the outcome from the CT analysis and the differences between them. Those samples were prepared at the Material Laboratory of Faculdade de Engenharia de Sorocaba, following the same procedures used in real case of concrete tests. The projections used in this work was obtained by Mini Computerized Tomograph of Uniso (MTCU), located at the Experimental Nuclear Physics Laboratory at University of Sorocaba. This tomograph operates with a gamma ray source of 241 Am (photons of 60 keV and 100 mCi of intensity) and a NaI(Tl) solid state detector. The system features translation and rotation scanning modes, a 100 mm effective field of view, and 1 mm spatial resolution. The image reconstruction problem is solved using Discrete Filtered Backprojection (FBP). (author)

  6. Computerized tomography-guided neurolytic splanchnic nerve block

    International Nuclear Information System (INIS)

    Henriquet, Franco; De Martini, Giuseppe; Roy, Maria Teresa; Pretrolesi, Fabio; Martinoli, Carlo; Cariati, Maurizio; Fiorentini, Franco.

    1997-01-01

    Computerized tomography-guided neurolytic splanchnic nerve block is a technique for relieving abdominal cancer pain; the goal is the alcoholic neurolytic interruption of the sensitive structures in retroperitoneal space. Computerized tomography yields accurate anatomical detailing and the course for needle placement and alcohol spread. January, 1993, to July, 1996, twenty-one bilateral splanchnic nerve blocks were performed through the posterior access. Forty-eight hours after alcoholism. 14 patients (66%) had complete pain regression; 52% of the patients needed no analgesics for 6 to 54 days and only 9 patients (42%) needed another low opioid therapy. Complications included hypotension and diarrhea in all cases. One had a cardiac arrest and diet 8 days after the procedure. There were no other complications. The whole procedure usually lasted 60 min (range: 45 to 90 min). Splanchnic nerve neurolysis is a useful treatment in the patients with severe chronic abdominal pain. It is used as a second line treatment when large lesions change celia anatomy and complicate the percutaneous block of the celiac plexus. Endosulfan, Malathion and Methyl parathion, on the metabolic rate of the estuarine clam, Villorita cyprinoides var. cochinensis, have been investigated. The animals exposed to the lower sublethal concentrations of Endosulfan, Malthion and Methyl parathion consumed oxygen at the rate of 1.60, 1.98 and 2.09 ml. 0 2 g - 1 h -1 respectively, while at the higher concentrations of the pesticides, consumption of oxygen by the animal dropped to nearly half the control value. When compared to Malathion and Methyl parathion. Endosulfan induced animals recorded a greater reduction in her percentage deviation (from control) of oxygen consumption, possibly due to hypoxia induced by the pollutants

  7. Quantitative analysis of cholesteatoma using high resolution computed tomography

    International Nuclear Information System (INIS)

    Kikuchi, Shigeru; Yamasoba, Tatsuya; Iinuma, Toshitaka.

    1992-01-01

    Seventy-three cases of adult cholesteatoma, including 52 cases of pars flaccida type cholesteatoma and 21 of pars tensa type cholesteatoma, were examined using high resolution computed tomography, in both axial (lateral semicircular canal plane) and coronal sections (cochlear, vestibular and antral plane). These cases were classified into two subtypes according to the presence of extension of cholesteatoma into the antrum. Sixty cases of chronic otitis media with central perforation (COM) were also examined as controls. Various locations of the middle ear cavity were measured in terms of size in comparison with pars flaccida type cholesteatoma, pars tensa type cholesteatoma and COM. The width of the attic was significantly larger in both pars flaccida type and pars tensa type cholesteatoma than in COM. With pars flaccida type cholesteatoma there was a significantly larger distance between the malleus and lateral wall of the attic than with COM. In contrast, the distance between the malleus and medial wall of the attic was significantly larger with pars tensa type cholesteatoma than with COM. With cholesteatoma extending into the antrum, regardless of the type of cholesteatoma, there were significantly larger distances than with COM at the following sites: the width and height of the aditus ad antrum, and the width, height and anterior-posterior diameter of the antrum. However, these distances were not significantly different between cholesteatoma without extension into the antrum and COM. The hitherto demonstrated qualitative impressions of bone destruction in cholesteatoma were quantitatively verified in detail using high resolution computed tomography. (author)

  8. Persistent asthma in adults: comparison of high resolution computed tomography of the lungs after one year of follow-up

    International Nuclear Information System (INIS)

    Cukier, Alberto; Stelmach, Rafael; Kavakama, Jorge Issamu; Terra Filho, Mario; Vargas, Francisco

    2001-01-01

    The aims of this study were to evaluate the role of high resolution computed tomography of the thorax in detecting abnormalities in chronic asthmatic patients and to determine the behavior of these lesions after at least one year. Fourteen persistent asthmatic patients with a mean forced expiratory volume in 1-second that was 63% of predicted and a mean forced expiratory volume in 1-second /forced vital capacity of 60% had two high resolution computed tomography separated by an interval of at least one year. All 14 patients had abnormalities on both scans. The most common abnormality was bronchial wall thickening, which was present in all patients on both computed tomography. Bronchiectasis was suggested on the first computed tomography in 5 of the 14 (36%) patients, but on follow-up, the bronchial dilatation had disappeared in 2 and diminished in a third. Only one patient had any emphysematous changes; a minimal persistent area of para septal emphysema was present on both scans. In 3 patients, a 'mosaic' appearance was observed on the first scan, and this persisted on the follow-up computed tomography. Two patients had persistent areas of mucoid impaction. In a third patient, mucus plugging was detected only on the second computed tomography. We conclude that there are many abnormalities on the high resolution computed tomography of patients with persistent asthma. Changes suggestive of bronchiectasis, namely bronchial dilatation, frequently resolve spontaneously. Therefore, the diagnosis of bronchiectasis by high resolution computed tomography in asthmatic patients must be made with caution, since bronchial dilatation can be reversible or can represent false dilatation. Non smoking chronic asthmatic subjects in this study had no evidence of centrilobular or panacinar emphysema. (author)

  9. Computerized tomography with X-rays: an instrument in the analysis physico-chemical between formations and drilling fluids interactions

    International Nuclear Information System (INIS)

    Coelho, Marcus Vinicius Cavalcante

    1998-01-01

    In this study it is demonstrated the applicability of the Computerized Tomography technique with x-rays to evaluate the reactivity degree between various drilling fluids and argillaceous sediments (Shales and Sandstones). The research has been conducted in the Rock-Fluid Interaction Pressure Simulator (RFIPS), where the possible physico-chemical alterations can be observed through successive tomography images, which are obtained during the flow of the fluid through the samples. In addition, it was noticed the formation of mud cake in Berea Sandstones samples in the RFIPS, though the Computerized Tomography with X-rays, when utilizing drilling fluids weighted with the baryte. (author)

  10. Ultra-high resolution optical coherence tomography for encapsulation quality inspection

    KAUST Repository

    Czajkowski, Jakub

    2011-08-28

    We present the application of ultra-high resolution optical coherence tomography (UHR-OCT) in evaluation of thin, protective films used in printed electronics. Two types of sample were investigated: microscopy glass and organic field effect transistor (OFET) structure. Samples were coated with thin (1-3 μm) layer of parylene C polymer. Measurements were done using experimental UHR-OCT device based on a Kerr-lens mode locked Ti: sapphire femtosecond laser, photonic crystal fibre and modified, free-space Michelson interferometer. Submicron resolution offered by the UHR-OCT system applied in the study enables registration of both interfaces of the thin encapsulation layer. Complete, volumetric characterisation of protective layers is presented, demonstrating possibility to use OCT for encapsulation quality inspection. © Springer-Verlag 2011.

  11. Dose profile measurement in computerized axial tomography equipment using thermoluminescent dosemeters

    International Nuclear Information System (INIS)

    Azorin V, J.C.; Falcony, C.; Azorin N, J.

    2000-01-01

    In this work are presented the results about measuring the radiation dose profile in two equipment of computerized axial tomography (Tac). Thermoluminescent dosemeters (Dtl) of LiF, Mg, Cu, P + Ptfe in form of disks were used which were developed and made in Mexico. The results showed that Dtl are appropriated for these type of studies. (Author)

  12. Use of computerized tomography in the Multibrauch Research and Technology Complex ''Eye microsurgery''

    International Nuclear Information System (INIS)

    Fedorov, S.N.; Ivashina, A.I.; Anisimov, S.I.; Prokopenko, L.N.; Moskvichev, A.L.

    1989-01-01

    The paper is devoted to analysis of the results of computerized tomography (CT) in 1000 patients examined in te Multibranch Research and Technology Complex ''Eye Microsurgery''. The specific feature of CT in this institution is that 52% of all investigations of ophthalmological patients fall to the share of eyeball abnormality and 40% - to a study of the other parts of the organ of vision. CT indications are extended for low tension glaucoma, complicated high myopia, and for monitoring the position of microsurgical implants. The use of CT is such a highly specialized medical institution as the MRTC ''Eye Microsurgery'' is considered indispensable

  13. Computerized tomography findings in nasolacrimal dysfunction

    International Nuclear Information System (INIS)

    Ishida, Toshio; Nakamura, Yasuhisa; Kumagai, Michiasa

    1985-01-01

    We examined 17 cases (22 lesions) with stenosis or obstruction in the lacrimal drainage system with the use of computerized tomography (CT). In idio pathic cases, the site of obstruction was located either in the upper nasolacrimal duct or at the junction of the lacrimal sac and the nasolacrimal duct. In post-traumatic cases, it was located in the lower nasolacrimal duct. The obstructed areas appeared as homogenous in CT image with CT values ranging between +60 and +80. These findings were suggestive of granulation tissue. The stenosed areas appeared, on the other hand, as areas of unequal density. Lacrimal passage appeared to be maintained through the low-density portion. The CT values of the lacrimal sac was around +40 in dacryocystitis and around +20 to +30 other cases. (author)

  14. Developmental approach towards high resolution optical coherence tomography for glaucoma diagnostics

    Science.gov (United States)

    Kemper, Björn; Ketelhut, Steffi; Heiduschka, Peter; Thorn, Marie; Larsen, Michael; Schnekenburger, Jürgen

    2018-02-01

    Glaucoma is caused by a pathological rise in the intraocular pressure, which results in a progressive loss of vision by a damage to retinal cells and the optical nerve head. Early detection of pressure-induced damage is thus essential for the reduction of eye pressure and to prevent severe incapacity or blindness. Within the new European Project GALAHAD (Glaucoma Advanced, Label free High Resolution Automated OCT Diagnostics), we will develop a new low-cost and high-resolution OCT system for the early detection of glaucoma. The device is designed to improve diagnosis based on a new system of optical coherence tomography. Although OCT systems are at present available in ophthalmology centres, high-resolution devices are extremely expensive. The novelty of the new Galahad system is its super wideband light source to achieve high image resolution at a reasonable cost. Proof of concept experiments with cell and tissue Glaucoma test standards and animal models are planned for the test of the new optical components and new algorithms performance for the identification of Glaucoma associated cell and tissue structures. The intense training of the software systems with various samples should result in a increased sensitivity and specificity of the OCT software system.

  15. Tuberculose pulmonar: achados na tomografia computadorizada de alta resolução do tórax em pacientes com doença em atividade comprovada bacteriologicamente Pulmonary tuberculosis: findings on high resolution computerized tomography of active disease on patients with bacteriological confirmation

    Directory of Open Access Journals (Sweden)

    CRISTIANE ALÓ CAMPOS

    2002-01-01

    Full Text Available Objetivo: Descrever os achados em pacientes com tuberculose pulmonar em atividade na tomografia computadorizada de alta resolução e o padrão de distribuição das lesões pelo parênquima pulmonar. Casuística e método: Foram analisadas retrospectivamente as tomografias de alta resolução de 42 pacientes com diagnóstico bacteriológico de tuberculose pulmonar ou forte suspeita clínica, com posterior confirmação bacteriológica. Resultados: Os principais sinais sugestivos de atividade encontrados foram nódulos do espaço aéreo (83%, nódulos centrolobulares (74%, aspecto de árvore em brotamento (67%, cavitações (67%, espessamento das paredes brônquicas (55%, consolidações (48%, opacidade em vidro fosco (21%, e espessamento do interstício pulmonar (9%. Conclusão: A tomografia computadorizada de alta resolução do tórax pode sugerir fortemente atividade da doença, sendo particularmente útil nos pacientes com baciloscopias negativas e/ou radiografias indeterminadas, permitindo a instituição de tratamento adequado, antes mesmo do crescimento da micobactéria em meio de cultura.Background: The aim of this study was to describe the signs of active tuberculosis in patients submitted to high resolution computerized tomography and the distribution of lesions along the pulmonary parenchyma. Material and methods: The high resolution CTs performed on 42 patients with tuberculosis either bacteriologically diagnosed or clinical suspected and later confirmed by bacteriological tests were studied. Results: The signs of disease activity observed were airspace nodule (83%, centrilobular nodule (74%, tree-in-bud pattern (67%, cavitations (67%, bronchial thickening (55%, parenchymal consolidations (48%, ground glass opacity (21% and thickening of the inter and intralobular septa (9%. Conclusion: High resolution computed tomography can be strongly suggestive of disease activity, is particularly helpful in patients with negative smear and

  16. Progressive systemic sclerosis: high-resolution computed tomography findings; Esclerose sistemica progressiva: aspectos na tomografia computadorizada de alta resolucao

    Energy Technology Data Exchange (ETDEWEB)

    Gasparetto, Emerson L.; Pimenta, Rodrigo; Ono, Sergio E.; Escuissato, Dante L. [Parana Univ., Curitiba, PR (Brazil). Hospital de Clinicas. Servico de Radiologia Medica]. E-mail: dante.luiz@onda.com.br; Inoue, Cesar [Parana Univ., Curitiba, PR (Brazil). Faculdade de Medicina

    2005-09-15

    Objective: To describe the high-resolution computed tomography findings in the lung of patients with systemic sclerosis, independently of the respiratory symptoms. Materials and methods: Seventy-three high-resolution computed tomography scans of 44 patients with clinical diagnosis of systemic sclerosis were reviewed and defined by the consensus of two radiologists. Results: Abnormalities were seen in 91.8% (n = 67) of the scans. The most frequent findings were reticular pattern (90.4%), ground-glass opacities (63%), traction bronchiectasis and bronchiolectasis (56.2%), esophageal dilatation (46.6%), honeycombing pattern (28.8%) and signs of pulmonary hypertension (15.6%). In most cases the lesions were bilateral (89%) and symmetrical (58.5%). The lesions were predominantly located in the basal (91.2%) and peripheral (92.2%) regions. Conclusion: In the majority of the patients, progressive systemic sclerosis can cause pulmonary fibrosis mainly characterized by reticular pattern with basal and peripheral distribution on high-resolution computed tomography. (author)

  17. Pulmonary complications of crack cocaine use: high-resolution computed tomography of the chest

    International Nuclear Information System (INIS)

    Mancano, Alexandre

    2008-01-01

    Here, we report high-resolution computed tomography (HRCT) findings in a patient who developed sudden hemoptysis, dyspnea and chest pain after smoking crack cocaine. Chest X-rays showed consolidations, primarily in the upper lobes, and HRCT scans showed ground glass attenuation opacities, consolidations and air-space nodules. A follow-up CT, after drug use discontinuation and administration of corticosteroids, showed partial resolution of pulmonary lesions and the appearance of cavitations. Clinical, imaging and laboratory findings led to a diagnosis of 'crack lung'. (author)

  18. Computerized tomography and conventional radiography: A comparison from the standpoint of X-ray physics and technology

    Energy Technology Data Exchange (ETDEWEB)

    Pfeiler, M; Linke, G [Siemens A.G., Erlangen (Germany, F.R.). Unternehmensbereich Medizinische Technik

    1979-08-01

    After a short explantation of the technical foundations of computerized tomography (CT) from terms used in conventional X-ray technique and CT the differences (dose distribution, image character) and similarities (quantum noise, beam quality) of both methods are discussed. Finally possible methods of quantitative evaluation of CT images and computation of longitudinal layers from a series of computerized tomograms are described. (author).

  19. Evaluation of the soil-seed environment through computerized tomography

    International Nuclear Information System (INIS)

    Modolo, Alcir Jose; Fernandes, Haroldo Carlos; Schaefer, Carlos Ernesto G.R.; Santos, Nerilson Terra; Silveira, Joao Cleber Modernel da

    2008-01-01

    The physical conditioning of the soil around seeds is of great importance for an adequate initial development of a crop, ensuring a healthy plant population. A suitable soil-seed contact is a prerequisite for a fast crop germination and good establishment. In this study, computerized tomography of millimeter resolution was used to determine the soil-seed environment in a no tillage system, immediately after soybean planting. A split plot design was used, in which the plots consisted of three contents of soil water, corresponding to 0.27; 0,31 and 0.36 kg kg -1 , respectively, and the split plots of four load levels applied by the compaction wheel, corresponding to 0, 50, 90 and 140 N, respectively. It was used a random block design, with four replications. The medium soil density in the seed area and the medium density profile in the sowing furrow were evaluated. According to the results, it may be concluded that: the loads applied by the compaction wheel increased soil density at the vertical planting level beneath planting depth as compared with values obtained before planting, and; the combination of wheel loads and soil water contents did not influence the mean soil density in the seed area. (author)

  20. High-resolution computed tomography of the lungs: the borderlands of normality

    International Nuclear Information System (INIS)

    Dalal, P.U.; Hansell, D.M.

    2006-01-01

    High-resolution computed tomography (HRCT) is now widely used in the assessment of airways and diffuse lung disease. Considerable literature on pathologic correlation has increased the understanding of the signs of disease seen on HRCT. However, neither the significance of subtle individual signs nor the spectrum of HRCT appearances in healthy lungs is well documented. HRCT signs that cause diagnostic uncertainty and the spectrum of findings that exist between definite normality and definite abnormality are discussed. (orig.)

  1. Findings of psychopathology and computerized tomography in neuropsychiatric diseases

    International Nuclear Information System (INIS)

    Gross, G.; Huber, G.; Schuettler, R.

    1982-01-01

    1978-1980 we examined 451 patients of the Psychiatric University Clinic of Bonn by computerized tomography. From 260 patients with characterized diseases of the brain and brain damages 78 patients had neuropsychiatric diseases of old age, i.e. cerebro-vascular processes (average age of 63.7 years) and 9 patients had primary degenerative processes of the brain (average age of 62.1 years). Patients with diseases of the cerebral vessels showed irreversible psychopathological syndromes in 87%. The rate of pathological findings in CT increases in relation to degree of severity of the chronic (irreversible) organic psychosyndromes from 76% in pseudoneurasthenics syndromes to 93% in patients with organic changes of personality and to 100% in patients with dementia. The ambiguity of the conception of the multi-infarct-dementia is discussed. Only 19% of the sample with irreversible psychopathological changes showed localized neurological deficits and infarctions in CT, but none of them more than one. In all patients with dementia a cortical atrophy was found. There is a significant positive correlation between cerebral atrophy in CT and irreversible organic psychosyndrome. These findings with computerized tomography demonstrate in accordance with earlier pneumoencephalographic findings that distinct types of irreversible psychosyndromes can be correlated to distinct types of cerebral atrophy. But these statistical correlations between the degree of the severity of the loss of psychic functions and the reduction of cerebral tissue are not necessarily valid for any single case. (orig.) [de

  2. Analyzing 3D xylem networks in Vitis vinifera using High Resolution Computed Tomography (HRCT)

    Science.gov (United States)

    Recent developments in High Resolution Computed Tomography (HRCT) have made it possible to visualize three dimensional (3D) xylem networks without time consuming, labor intensive physical sectioning. Here we describe a new method to visualize complex vessel networks in plants and produce a quantitat...

  3. Bronchial asthma: correlation of high resolution computerized tomography findings with clinical data; Asma bronquica: correlacao de achados em tomografia computadorizada de alta resolucao com dados clinicos

    Energy Technology Data Exchange (ETDEWEB)

    Mogami, Roberto [Universidade do Estado, Rio de Janeiro, RJ (Brazil). Servico de Radiologia; Marchiori, Edson [Universidade Federal Fluminense, Niteroi, RJ (Brazil). Dept. de Radiologia; Kirk, Kennedy; Capone, Domenico [Universidade do Estado, Rio de Janeiro, RJ (Brazil). Servico de Pneumologia; Daltro, Pedro [Instituto Fernandes Figueira, Rio de Janeiro, RJ (Brazil). Servico de Radiologia

    1999-04-01

    In this work we did a sectional study of 31 asthmatic patients with several levels of disease severity, which were submitted to high resolution computed tomography of the thorax and spirometry, between the months of July, 1995 and August, 1997. The tomographic findings were correlated with the clinical classification of the patients and the most frequent tomographic findings were bronchial wall thickening, bronchial dilatation, air trapping, centrilobular opacities, cicatricial linear shadows, mucoid impaction, emphysema and atelectasis. In asthmatic patients of long duration we observed small airway disease and irreversible lesions as the predominant findings. In smoking patients there was no high frequency of emphysema. (author)

  4. Ultra-High-Resolution Computed Tomography of the Lung: Image Quality of a Prototype Scanner

    OpenAIRE

    Kakinuma, Ryutaro; Moriyama, Noriyuki; Muramatsu, Yukio; Gomi, Shiho; Suzuki, Masahiro; Nagasawa, Hirobumi; Kusumoto, Masahiko; Aso, Tomohiko; Muramatsu, Yoshihisa; Tsuchida, Takaaki; Tsuta, Koji; Maeshima, Akiko Miyagi; Tochigi, Naobumi; Watanabe, Shun-ichi; Sugihara, Naoki

    2015-01-01

    Purpose: The image noise and image quality of a prototype ultra-high-resolution computed tomography (U-HRCT) scanner was evaluated and compared with those of conventional high-resolution CT (C-HRCT) scanners. Materials and Methods: This study was approved by the institutional review board. A U-HRCT scanner prototype with 0.25 mm × 4 rows and operating at 120 mAs was used. The C-HRCT images were obtained using a 0.5 mm × 16 or 0.5 mm × 64 detector-row CT scanner operating at 150 mAs. Images fr...

  5. Contribution of computerized tomography to diagnosis of primary hyperaldosteronism

    International Nuclear Information System (INIS)

    Hrabaneova, J.; Stribrna, J.; Bultasova, H.; Karasova, L.; Placer, Z.; Pinsker, P.

    1987-01-01

    Two cases are reported of computerized tomography (CT) examination for proof of suspect primary hyperaldosteronism caused by adenoma of the adrenals. The findings were then confirmed surgically and histologically. CT was again found to be an invaluable tool for differential diagnosis of this condition, which spared the patients demanding invasive examinations and clearly differentiated primary hyperaldosteronism from adrenal cortex hyperplasia. This is mainly important for the fact that adenoma or more rarely carcinoma causing primary hyperaldosteronism can surgically be removed. (L.O.). 2 figs., 2 tabs., 6 refs

  6. A high-speed computerized tomography image reconstruction using direct two-dimensional Fourier transform method

    International Nuclear Information System (INIS)

    Niki, Noboru; Mizutani, Toshio; Takahashi, Yoshizo; Inouye, Tamon.

    1983-01-01

    The nescessity for developing real-time computerized tomography (CT) aiming at the dynamic observation of organs such as hearts has lately been advocated. It is necessary for its realization to reconstruct the images which are markedly faster than present CTs. Although various reconstructing methods have been proposed so far, the method practically employed at present is the filtered backprojection (FBP) method only, which can give high quality image reconstruction, but takes much computing time. In the past, the two-dimensional Fourier transform (TFT) method was regarded as unsuitable to practical use because the quality of images obtained was not good, in spite of the promising method for high speed reconstruction because of its less computing time. However, since it was revealed that the image quality by TFT method depended greatly on interpolation accuracy in two-dimensional Fourier space, the authors have developed a high-speed calculation algorithm that can obtain high quality images by pursuing the relationship between the image quality and the interpolation method. In this case, radial data sampling points in Fourier space are increased to β-th power of 2 times, and the linear or spline interpolation is used. Comparison of this method with the present FBP method resulted in the conclusion that the image quality is almost the same in practical image matrix, the computational time by TFT method becomes about 1/10 of FBP method, and the memory capacity also reduces by about 20 %. (Wakatsuki, Y.)

  7. Diagnostic perspectives of mobile x-ray computerized tomography

    International Nuclear Information System (INIS)

    Portnoj, L.M.; Dibirov, M.P.; Denisova, L.B.

    1992-01-01

    Mobile x-ray computerized tomography (CT) and an organization and methodological scheme of its application were assessed. CT is realized in special hospitals of large regions, where the patients with the optimal indications for CT are assembled. Over 15000 examinations were carried out with the use of the suggested CT program over 4 years, that resulted in detection of 1295 brain tumors, 804 cases with neoplastic involvement of the abdominal cavity and the retroperitoneal space. Wide application of mobile CT devices according to the program will help to decide the problem of unavailability of such examinations. One mobile device may replace 3 permanent CT devices

  8. Single photon emission computerized tomography

    International Nuclear Information System (INIS)

    Hooge, P. de.

    1983-01-01

    In this thesis two single-photon emission tomographic techniques are presented: (a) longitudinal tomography with a rotating slanting-hole collimator, and (b) transversal tomography with a rotating gamma camera. These methods overcome the disadvantages of conventional scintigraphy. Both detection systems and the image construction methods are explained and comparisons with conventional scintigraphy are drawn. One chapter is dedicated to the determination of system parameters like spatial resolution, contrast, detector uniformity, and size of the object, by phantom studies. In separate chapters the results are presented of detection of tumors and metastases in the liver and the liver hilus; skeletal diseases; various pathological aberrations of the brain; and myocardial perfusion. The possible use of these two ect's for other organs and body areas is discussed in the last chapter. (Auth.)

  9. Ultra high resolution tomography

    Energy Technology Data Exchange (ETDEWEB)

    Haddad, W.S.

    1994-11-15

    Recent work and results on ultra high resolution three dimensional imaging with soft x-rays will be presented. This work is aimed at determining microscopic three dimensional structure of biological and material specimens. Three dimensional reconstructed images of a microscopic test object will be presented; the reconstruction has a resolution on the order of 1000 A in all three dimensions. Preliminary work with biological samples will also be shown, and the experimental and numerical methods used will be discussed.

  10. Contribution to differential diagnosis of lumbar spine disc hernia by computerized tomography

    International Nuclear Information System (INIS)

    Dolansky, J.

    1989-01-01

    The significance is discussed of computerized tomography in differential diagnosis of disc hernias of the lumbar spine. A simple technique is described that allows to differentiate disc hernias from epidural vein varices. It mostly includes repeat imaging of the same body section and/or the application of a contrast medium. (L.O.). 2 figs., 4 refs

  11. Computerized detection of acute ischemic stroke in brain computed tomography images

    International Nuclear Information System (INIS)

    Nagashima, Hiroyuki; Shiraishi, Akihisa; Harakawa, Tetsumi; Shiraishi, Junji; Doi, Kunio; Sunaga, Shinichi

    2009-01-01

    The interpretation of acute ischemic stroke (AIS) in computed tomography (CT) images is a very difficult challenge for radiologists. To assist radiologists in CT image interpretation, we have developed a computerized method for the detection of AIS using 100 training cases and 60 testing cases. In our computerized method, the inclination of the isotropic brain CT volume data is corrected by rotation and shifting. The subtraction data for the contralateral volume is then derived by subtraction from the mirrored (right-left reversed) volume data. Initial candidates suspected to have experienced AIS were identified using multiple-thresholding and filtering techniques. Twenty-one image features of these candidates were extracted and applied to a rule-based test to identify final candidates for AIS. The detection sensitivity values for the training cases and for the testing cases were 95.0% with 3.1 false positives per case and 85.7% with 3.4 false positives per case, respectively. Our computerized method showed good performance in the detection of AIS by CT and is expected to be useful in decision-making by radiologists. (author)

  12. High resolution computed tomography of the middle ear

    International Nuclear Information System (INIS)

    Ikeda, Katsuhisa; Sakurai, Tokio; Saijo, Shigeru; Kobayashi, Toshimitsu

    1983-01-01

    High resolution computed tomography was performed in 57 cases with various middle ear diseases (chronic otitis media, otitis media with effusion, acute otitis media and atelectasis). Although further improvement in detectability is necessary in order to discriminate each type of the soft tissue lesions, CT is the most useful method currently available in detecting the small structures and soft tissue lesions of the middle ear. In particular, the lesions at the tympanic isthmus and tympanic fold could very clearly be detected only by CT. In acute otitis media, lesions usually started in the attic and spread to the mastoid air cells. In otitis media with effusion, the soft tissue shadow was ovserved in the attic and mastoid air cell. CT is valuable in diagnosis, evaluation of the treatment and prognosis, and analysis of pathophysiology in the middle ear diseases. (author)

  13. Contrast Dose and Radiation Dose Reduction in Abdominal Enhanced Computerized Tomography Scans with Single-phase Dual-energy Spectral Computerized Tomography Mode for Children with Solid Tumors

    OpenAIRE

    Tong Yu; Jun Gao; Zhi-Min Liu; Qi-Feng Zhang; Yong Liu; Ling Jiang; Yun Peng

    2017-01-01

    Background: Contrast dose and radiation dose reduction in computerized tomography (CT) scan for adult has been explored successfully, but there have been few studies on the application of low-concentration contrast in pediatric abdominal CT examinations. This was a feasibility study on the use of dual-energy spectral imaging and adaptive statistical iterative reconstruction (ASiR) for the reduction of radiation dose and iodine contrast dose in pediatric abdominal CT patients with solid tumors...

  14. High-resolution time-lapse tomography of rat vertebrae during compressive loading: deformation response analysis

    Czech Academy of Sciences Publication Activity Database

    Fíla, Tomáš; Kytýř, Daniel; Zlámal, Petr; Kumpová, Ivana; Doktor, Tomáš; Koudelka_ml., Petr; Jiroušek, Ondřej

    2014-01-01

    Roč. 9, May (2014), C05054 ISSN 1748-0221. [International workshop on radiation imaging detectors /15./. Paris, 23.06.2013-27.06.2013] R&D Projects: GA ČR(CZ) GAP105/10/2305; GA MŠk(CZ) LO1219 Institutional support: RVO:68378297 Keywords : image reconstruction in medical imaging * computerized tomography * computed radiography Subject RIV: JJ - Other Materials Impact factor: 1.399, year: 2014 http://iopscience.iop.org/1748-0221/9/05/C05054

  15. Prediction of traumatic avascular necrosis of the femoral head by single photon emission computerized tomography and computerized tomography: an experimental study in dogs

    Directory of Open Access Journals (Sweden)

    SHEN Feng

    2012-02-01

    Full Text Available 【Abstract】 Objective: To evaluate the femoral head perfusion and to predict the traumatic avascular necrosis (AVN of the femoral head by single photon emission computerized tomography and computerized tomography (SPECT/CT. Methods: Totally 18 adult beagle dogs were divided randomly into three equal-sized (n=6 groups. Subsequently different degrees of ischemia model were developed by destroying blood vessels of the femoral head. The left hip received sham operation as normal control and the right hip underwent blood interruption. In Group A, the ligamentum teres was cut off. In Group B, the marrow cavity of the right femoral neck was destroyed while in Group C, the soft tissues at the base of the femoral neck were stripped in addition to the resection of the ligamentum teres and destruction of the marrow cavity. Three hours after surgery, SPECT/CT was performed. Laser Doppler Flowmetry (LDF measurements were also obtained at three different time points (before operation, immediately and three hours after operation in order to assess the change process of blood supply to the femoral head. Results: SPECT/CT showed no significant difference in the radionuclide uptake between the right and left femoral heads in Group A (t=-0.09, P=0.94 and Group B (t= 0.52, P=0.62. However, in Group C, it was 261±62 for the right femoral head, only 12% of that in the left femoral head. LDF measurements indicated that the femoral head perfusion was decreased from (45.0±3.3 PU to (39.1±3.7 PU in Group A, from (44.0±2.7 PU to (34.3±2.6 PU in Group B, and from (47.3±2.1 PU to (4.96±0.6 PU in Group C immediately after operation. However, the perfusion was restored and returned to normal values three hours after operation except in Group C. Conclusion: SPECT/CT could assess the perfusion of the femoral head semiquantitatively, which might be useful in predicting the development of traumatic AVN. Key words: Femur head necrosis; Femoral head; Tomography, emission

  16. Evaluation of Biomaterials Using Micro-Computerized Tomography

    International Nuclear Information System (INIS)

    Torris, A. T. Arun; Columbus, K. C. Soumya; Saaj, U. S.; Krishnan, Kalliyana V.; Nair, Manitha B.

    2008-01-01

    Micro-computed tomography or Micro-CT is a high resolution, non-invasive, x-ray scanning technique that allows precise three-dimensional imaging and quantification of micro-architectural and structural parameters of objects. Tomographic reconstruction is based on a cone-beam convolution-back-projection algorithm. Micro-architectural and structural parameters such as porosity, surface area to volume ratio, interconnectivity, pore size, wall thickness, anisotropy and cross-section area of biomaterials and bio-specimens such as trabecular bone, polymer scaffold, bio-ceramics and dental restorative were evaluated through imaging and computer aided manipulation of the object scan data sets.

  17. Can duplex Doppler ultrasound replace computerized tomography in staging patients with renal cell carcinoma?

    NARCIS (Netherlands)

    Bos, SD; Mensink, HJA

    The purpose of this study was to evaluate the accuracy and reliability of duplex Doppler ultrasound (US) and computerized tomography (CT) in staging patients with renal cell carcinoma (RCC). Sixty-six patients were evaluated pre-operatively with duplex Doppler ultrasound and CT. The results were

  18. Computerized tomography anatomy of the kidneys and retroperitoneal space

    International Nuclear Information System (INIS)

    Savchenko, A.P.; Mamaev, V.V.; Pkhakadze, Eh.G.

    1989-01-01

    The authors described the anatomy of the kidneys and retroperitoneal space in health on the basis of computerized tomography (CT) of 90 patients. Five typical levels in CT (ensuring all necessary data on roentgenomorphological trains of the kidneys and retroperitoneal space in the kidney area) were singled out. Some roentgenometric data on kidney cross-sections as well as the quantitative densitometric characterization of the parenchyma of the kidneys, renal sinus and adjacent tissues were presented. X-ray anatomy of the renal fiscia, pararenal space and perirenal fatty space of the kidney with different parts of the tetroperitoneal space was described

  19. Dental status of three Egyptian mummies: radiological investigation by multislice computerized tomography.

    Science.gov (United States)

    Gerloni, Alessandro; Cavalli, Fabio; Costantinides, Fulvio; Costantinides, Fulvia; Bonetti, Stefano; Paganelli, Corrado

    2009-06-01

    The aim of the study was to provide a paleopathologic and radiologic overview of the jaws and teeth of 3 Egyptian mummies preserved in the Civic Museum of History and Art in Trieste. Computerized tomography (CT) imaging and postprocessing techniques were used to examine the oral structures. A 16-slice CT scanner was used (Aquilion 16; Toshiba Medical Systems Europe, Zoetermeer, The Netherlands). Scans were obtained at high resolution. Orthogonal-plane and 3-dimensional (3D) reconstructions were created along with curved reconstructions of the lower and upper jaws. Determination of decayed/missing teeth (DMT) and decayed/missing/tooth surfaces (DMTs) were made with 3D images. Analyses revealed differences in the embalming techniques and state of preservation of the bodies. Marked wear of the occlusal surfaces was a characteristic finding in all of the mummies. The DMT and DMTs were low compared with values for contemporary populations. Two mummies had fully erupted third molars. All mummies exhibited bone changes consistent with periodontitis. The CT evaluations of the oral structures of the mummies provided insight into the dental status and oral diseases of these ancient Egyptians. The low DMT and DMTs values and indications of periodontitis may be associated with the lifestyle of these Egyptians. The fully erupted and well aligned third molars may represent a morphologic adaptation of the arches to the muscular activity associated with grinding tough foods.

  20. High-resolution-cone beam tomography analysis of bone microarchitecture in patients with acromegaly and radiological vertebral fractures.

    Science.gov (United States)

    Maffezzoni, Filippo; Maddalo, Michele; Frara, Stefano; Mezzone, Monica; Zorza, Ivan; Baruffaldi, Fabio; Doglietto, Francesco; Mazziotti, Gherardo; Maroldi, Roberto; Giustina, Andrea

    2016-11-01

    Vertebral fractures are an emerging complication of acromegaly but their prediction is still difficult occurring even in patients with normal bone mineral density. In this study we evaluated the ability of high-resolution cone-beam computed tomography to provide information on skeletal abnormalities associated with vertebral fractures in acromegaly. 40 patients (24 females, 16 males; median age 57 years, range 25-72) and 21 healthy volunteers (10 females, 11 males; median age 60 years, range: 25-68) were evaluated for trabecular (bone volume/trabecular volume ratio, mean trabecular separation, and mean trabecular thickness) and cortical (thickness and porosity) parameters at distal radius using a high-resolution cone-beam computed tomography system. All acromegaly patients were evaluated for morphometric vertebral fractures and for mineral bone density by dual-energy X-ray absorptiometry at lumbar spine, total hip, femoral neck, and distal radius. Acromegaly patients with vertebral fractures (15 cases) had significantly (p acromegaly patients did not have significant differences in bone density at either skeletal site. Patients with acromegaly showed lower bone volume/trabecular volume ratio (p = 0.003) and mean trabecular thickness (p acromegaly. High-resolution cone-beam computed tomography at the distal radius may be useful to evaluate and predict the effects of acromegaly on bone microstructure.

  1. Evaluation of the absorbed dose in odontological computerized tomography; Avaliacao da dose absorvida em tomografia computadorizada odontologica

    Energy Technology Data Exchange (ETDEWEB)

    Legnani, Adriano; Schelin, Hugo R; Rocha, Anna Silvia P.S. da, E-mail: schelin@utfpr.edu.b, E-mail: anna@utfpr.edu.b [Universidade Tecnologica Federal do Parana (UTFPR), Curitiba, PR (Brazil); Khoury, Helen J., E-mail: khoury@ufpe.b [Universidade Federal de Pernambuco (UFPE), Recife, PE (Brazil)

    2011-10-26

    This paper evaluated the absorbed dose at the surface entry known as 'cone beam computed tomography' (CBCT) in odontological computerized tomography. Examination were simulated with CBCT for measurements of dose. A phantom were filled with water, becoming scatter object of radiation. Thermoluminescent dosemeters were positioned on points correspondent to eyes and salivary glands

  2. Study on a high resolution positron emission tomography scanner for brain study

    International Nuclear Information System (INIS)

    Nohara, N.; Tomitani, T.; Yamamoto, M.; Murayama, H.; Tanaka, E.

    1990-01-01

    The spatial resolution of positron emission tomography (PET) scanners is usually limited by the finite size of crystals such as bismuth germanate (BGO). To attain high resolution as well as high sensitivity, it is essential to use a large number of small BGO crystals arranged in close-packing on circular rings. In developing high resolution PET scanners, however, there are two physical factors limiting the spatial resolution. One is the finite range of positrons before annihilation and the other the deviation from 180 degrees of annihilation photons. The effect of the factors on the spatial resolution has been evaluated for positron-emitting sources as a function of detector ring radius. A high resolution PET scanner has been developed for brain study, aiming to have spatial resolutions as high as less than 4-mm FWHM in tomographic plane and less than 6-mm FWHM in axial direction at the detector ring center. For the goal of the high resolutions a multi-segment type of photomultiplier tubes has been specially designed and developed, which allows one tube to be directly coupled by four BGO crystals. The scanner consists of five detector rings of 47-cm in diameter, using all 1200 BGO crystals each measuring 5 mm x 12 mm x 30 mm. The scanner provides simultaneous 9 images by combination of in-plane and cross-plane, offering a 24-cm dia. x7.4-cm field-of-view. Physical performance of the scanner was investigated. At the ring center, the spatial resolution in the tomographic plane was measured to be 3.5-mm FWHM. The axial resolution was measured to be 5.7-mm FWHM for in-plane and 5.3-mm FWHM for cross-plane. Sensitivity for a 20-cm dia. uniform source was measured to be 9.5 kcps/μCi/ml for in-plane and 15.3 kcps/μCi/ml for cross-plane. (J.P.N.)

  3. Novel Application of Micro-Computerized Tomography for Morphologic Characterization of the Murine Penis.

    Science.gov (United States)

    O'Neill, Marisol; Huang, Gene O; Lamb, Dolores J

    2017-12-01

    The murine penis model has enriched our understanding of anomalous penile development. The morphologic characterization of the murine penis using conventional serial sectioning methods is labor intensive and prone to errors. To develop a novel application of micro-computerized tomography (micro-CT) with iodine staining for rapid, non-destructive morphologic study of murine penis structure. Penises were dissected from 10 adult wild-type mice and imaged using micro-CT with iodine staining. Images were acquired at 5-μm spatial resolution on a Bruker SkyScan 1272 micro-CT system. After images were acquired, the specimens were washed of any remaining iodine and embedded in paraffin for conventional histologic examination. Histologic and micro-CT measurements for all specimens were made by 2 independent observers. Measurements of penile structures were made on virtual micro-CT sections and histologic slides. The Lin concordance correlation coefficient demonstrated almost perfect strength of agreement for interobserver variability for histologic section (0.9995, 95% CI = 0.9990-0.9997) and micro-CT section (0.9982, 95% CI = 0.9963-0.9991) measurements. Bland-Altman analysis for agreement between the 2 modalities of measurement demonstrated mean differences of -0.029, 0.022, and -0.068 mm for male urogenital mating protuberance, baculum, and penile glans length, respectively. There did not appear to be a bias for overestimation or underestimation of measured lengths and limits of agreement were narrow. The enhanced ability offered by micro-CT to phenotype the murine penis has the potential to improve translational studies examining the molecular pathways contributing to anomalous penile development. The present study describes the first reported use of micro-CT with iodine staining for imaging the murine penis. Producing repeated histologic sections of identical orientation was limited by inherent imperfections in mounting and tissue sectioning, but this was

  4. Spontaneous intracerebral haematomas - the influence of computerized tomography on the results of surgery

    International Nuclear Information System (INIS)

    Kolodziejczyk, D.

    1981-01-01

    The report covers 30 patients of 10 to 74 years of age who has hard spontaneous intracerebral haematomas in the time from 1975 to 1980 and had been operated on after diagnosing by means of computerized tomography. The total mortality rate was 40% and was not significantly different from the total operative result obtained by other authors in the CT-period, but it compares poor to the pre-CT-aera. This deterioration despite improved diagnoses might be an effect of computerized tomography on the operating surgeon. Out of 18 survivors, 8 were completely healed. 4 patients kept some neurological symptoms, but could manage everyday life on their own. 6 patients kept serious neurological defects needing care. The influence of neurological-clinical parameters on the final operation result hasn't lost its importance in the CT-aera. The value of CT for the therapy of intracerebral haematomas lies in course control which often justifies a conservative proceeding with good absorption tendency taking into consideration the clinical-neurological picture, despite the persistence of growing and displacing processes. (orig./MG) [de

  5. Evaluation of the absorbed dose in odontological computerized tomography; Avaliacao da dose absorvida em tomografia computadorizada odontologica

    Energy Technology Data Exchange (ETDEWEB)

    Legnani, Adriano; Schelin, Hugo R.; Rocha, Anna Silvia P.S. da, E-mail: schelin@utfpr.edu.b, E-mail: anna@utfpr.edu.b [Universidade Tecnologica Federal do Parana (UTFPR), Curitiba, PR (Brazil); Khoury, Helen J., E-mail: khoury@ufpe.b [Universidade Federal de Pernambuco (UFPE), Recife, PE (Brazil)

    2011-10-26

    This paper evaluated the absorbed dose at the surface entry known as 'cone beam computed tomography' (CBCT) in odontological computerized tomography. Examination were simulated with CBCT for measurements of dose. A phantom were filled with water, becoming scatter object of radiation. Thermoluminescent dosemeters were positioned on points correspondent to eyes and salivary glands

  6. Computerized transverse tomography of vascular lesions of the brain. I. Arteriovenous malformations

    International Nuclear Information System (INIS)

    Pressman, B.D.; Kirkwood, J.R.; Davis, D.O.

    1975-01-01

    Computerized transverse tomography (CTT) of the brain is a recently developed method which allows non-invasive roentgenologic evaluation of intracranial disease. Since its inception, major attention has been given to the diagnosis and evaluation of tumors, clots, infarcts, venticular size, and orbital lesions. The purpose of this report is to discuss the application of CTT to the diagnosis and evaluation of intracerebral arteriovenous malformations. (U.S.)

  7. High resolution functional photoacoustic tomography of breast cancer

    Energy Technology Data Exchange (ETDEWEB)

    Li, Xiaoqi; Yao, Lei; Xi, Lei; Jiang, Huabei, E-mail: hjiang@bme.ufl.edu [Department of Biomedical Engineering, University of Florida, Gainesville, Florida 32611 (United States); Heldermon, Coy D. [Department of Medicine, University of Florida, Gainesville, Florida 32611 (United States)

    2015-09-15

    Purpose: To evaluate the feasibility of functional photoacoustic tomography (fPAT) for high resolution detection and characterization of breast cancer and to demonstrate for the first time quantitative hemoglobin concentration and oxygen saturation images of breasts that were formed with model-based reconstruction of tomographic photoacoustic data. Methods: The study was HIPAA compliant and was approved by the university institutional review board. Written informed consents were obtained from all the participants. Ten cases, including six cancer and four healthy (mean age = 50 yr; age range = 41–66 yr), were examined. Functional images of breast tissue including absolute total hemoglobin concentration (Hb{sub T}) and oxygen saturation (StO{sub 2}%) were obtained by fPAT and cross validated with magnetic resonance imaging (MRI) readings and/or histopathology. Results: Hb{sub T} and StO{sub 2}% maps from all six pathology-confirmed cancer cases (60%) show clear detection of tumor, while MR images indicate clear detection of tumor for five of six cancer cases; one small tumor was read as near-complete-resolution by MRI. The average Hb{sub T} and StO{sub 2}% value of suspicious lesion area for the cancer cases was 61.6 ± 18.9 μM/l and 67.5% ± 5.2% compared to 25.6 ± 7.4 μM/l and 65.2% ± 3.8% for background normal tissue. Conclusions: fPAT has the potential to be a significant add-on in breast cancer detection and characterization as it provides submillimeter resolution functional images of breast lesions.

  8. High-resolution x-ray computed tomography to understand ruminant phylogeny

    Science.gov (United States)

    Costeur, Loic; Schulz, Georg; Müller, Bert

    2014-09-01

    High-resolution X-ray computed tomography has become a vital technique to study fossils down to the true micrometer level. Paleontological research requires the non-destructive analysis of internal structures of fossil specimens. We show how X-ray computed tomography enables us to visualize the inner ear of extinct and extant ruminants without skull destruction. The inner ear, a sensory organ for hearing and balance has a rather complex three-dimensional morphology and thus provides relevant phylogenetical information what has been to date essentially shown in primates. We made visible the inner ears of a set of living and fossil ruminants using the phoenix x-ray nanotom®m (GE Sensing and Inspection Technologies GmbH). Because of the high absorbing objects a tungsten target was used and the experiments were performed with maximum accelerating voltage of 180 kV and a beam current of 30 μA. Possible stem ruminants of the living families are known in the fossil record but extreme morphological convergences in external structures such as teeth is a strong limitation to our understanding of the evolutionary history of this economically important group of animals. We thus investigate the inner ear to assess its phylogenetical potential for ruminants and our first results show strong family-level morphological differences.

  9. Normal anatomical measurements in cervical computerized tomography

    International Nuclear Information System (INIS)

    Zaunbauer, W.; Daepp, S.; Haertel, M.

    1985-01-01

    Radiodiagnostically relevant normal values and variations for measurements of the cervical region, the arithmetical average and the standard deviation were determined from adequate computer tomograms on 60 healthy women and men, aged 20 to 83 years. The sagittal diameter of the prevertebral soft tissue and the lumina of the upper respiratory tract were evaluated at exactly defined levels between the hyoid bone and the incisura jugularis sterni. - The thickness of the aryepiglottic folds, the maximal sagittal and transverse diameters of the thyroid gland and the calibre of the great cervical vessels were defined. - To assess information about laryngeal function in computerized tomography, measurements of distances between the cervical spine and anatomical fixed points of the larynx and hypopharynx were made as well as of the degree of vocal cord movement during normal respiration and phonation. (orig.) [de

  10. High resolution computed tomography of the post partum pituitary gland

    International Nuclear Information System (INIS)

    Hinshaw, D.B.; Hasso, A.N.; Thompson, J.R.; Davidson, B.J.

    1984-01-01

    Eight volunteer post partum female patients were examined with high resolution computed tomography during the week immediately after delivery. All patients received high dose (40-70 gm) intravenous iodine contrast administration. The scans were examined for pituitary gland height, shape and homogeneity. All of the patients had enlarged glands by the traditional standards (i.e. gland height of 8 mm or greater). The diaphragma sellae in every call bulged upward with a convex domed appearance. The glands were generally inhomogeneous. One gland had a 4 mm focal well defined area of decreased attenuation. Two patients who were studied again months later had glands which had returned to ''normal'' size. The enlarged, upwardly convex pituitary gland appears to be typical and normal for the recently post partum period. (orig.)

  11. A review of X-ray computed axial tomography

    International Nuclear Information System (INIS)

    Schmidt, M.

    1989-01-01

    A review of Computed axial tomography (CAT) scanning literature outlining the theoretical and practical aspects of this technique with application in both medical diagnosis and industrial non-destructive inspection (NDI) is presented. Practical aspects of CAT scanning discussed include : radiation sources, currently available spatial and contrast resolution limits and the evolution of the computerized tomography (CT) system. It was found that monochromatic gamma rays are preferred to X-rays, especially for very high density materials, and that in medical CAT scanning, the special resolution is only, 0.5 mm while spatial resolutions of less than 50μm have been achieved in NDI. An increased number of scientific and industrial applications are anticipated (e.g. for studying sintering reactions), as the capital cost of CAT scanning decreased. 13 refs., 9 figs., 2 tabs

  12. High-resolution photoacoustic tomography of resting-state functional connectivity in the mouse brain

    OpenAIRE

    Nasiriavanaki, Mohammadreza; Xia, Jun; Wan, Hanlin; Bauer, Adam Quentin; Culver, Joseph P.; Wang, Lihong V.

    2013-01-01

    The increasing use of mouse models for human brain disease studies presents an emerging need for a new functional imaging modality. Using optical excitation and acoustic detection, we developed a functional connectivity photoacoustic tomography system, which allows noninvasive imaging of resting-state functional connectivity in the mouse brain, with a large field of view and a high spatial resolution. Bilateral correlations were observed in eight functional regions, including the olfactory bu...

  13. Computerized industrial tomography

    International Nuclear Information System (INIS)

    Ashraf, M.M.

    1999-01-01

    Computerized Tomographic (CT) has been used for a number of applications in the field of medicine and industry. For the last couple of years, the technique has been applied for the material characterization and detection of defects and flaws inside the industrial components of nuclear, aerospace and missile industries. A CT scanner of first generation was developed at the institute. The scanner has been used to demonstrate couple of applications of CT in the field of non destructive testing of materials. The data acquired by placing the test objects at various angles and scanning the object through a source detector assembly has been processed on a Pentium computer for image reconstruction using a filtered back projection method. The technique has been developed which can be modified and improved to study various other applications in materials science and a modern computerized tomographic facility can be established. (author)

  14. Ultra-High Resolution Optical Coherence Tomography Imaging of Unilateral Drusen in a 31 Year Old Woman.

    Science.gov (United States)

    de Carlo, Talisa E; Adhi, Mehreen; Lu, Chen D; Duker, Jay S; Fujimoto, James G; Waheed, Nadia K

    We report a case of widespread unilateral drusen in a healthy 31 year old Caucasian woman using multi-modal imaging including ultra-high resolution optical coherence tomography (UHR-OCT). Dilated fundus exam showed multiple drusen-like lesions in the posterior pole without heme or fluid. Fundus auto fluorescence demonstrated hyperautofluorescent at the deposits. Fluorescein angiography revealed mild hyperfluorescence and staining of the lesions. Spectral-domain optical coherence tomography (SD-OCT) OS showed accumulations in the temporal macula at Bruch's membrane. UHR-OCT provided improved axial resolution compared to the standard 5 μm on the commercial SD-OCT and confirmed the presence of deposits in Bruch's membrane, consistent with drusen. The retinal layers were draped over the excrescences but did not show any disruption.

  15. High-resolution tomography of positron emitters with clustered pinhole SPECT

    Energy Technology Data Exchange (ETDEWEB)

    Goorden, Marlies C; Beekman, Freek J [Section of Radiation Detection and Medical Imaging, Applied Sciences, Delft University of Technology, Mekelweg 15, 2629 JB Delft (Netherlands)], E-mail: m.c.goorden@tudelft.nl

    2010-03-07

    State-of-the-art small-animal single photon emission computed tomography (SPECT) enables sub-half-mm resolution imaging of radio-labelled molecules. Due to severe photon penetration through pinhole edges, current multi-pinhole SPECT is not suitable for high-resolution imaging of photons with high energies, such as the annihilation photons emitted by positron emitting tracers (511 keV). To deal with this edge penetration, we introduce here clustered multi-pinhole SPECT (CMP): each pinhole in a cluster has a narrow opening angle to reduce photon penetration. Using simulations, CMP is compared with (i) a collimator with traditional pinholes that is currently used for sub-half-mm imaging of SPECT isotopes (U-SPECT-II), and (ii), like (i) but with collimator thickness adapted to image high-energy photons (traditional multi-pinhole SPECT, TMP). At 511 keV, U-SPECT-II is able to resolve the 0.9 mm rods of an iteratively reconstructed Jaszczak-like capillary hot rod phantom, and while TMP only leads to small improvements, CMP can resolve rods as small as 0.7 mm. Using a digital tumour phantom, we show that CMP resolves many details not assessable with standard USPECT-II and TMP collimators. Furthermore, CMP makes it possible to visualize uptake of positron emitting tracers in sub-compartments of a digital mouse striatal brain phantom. This may open up unique possibilities for analysing processes such as those underlying the function of neurotransmitter systems. Additional potential of CMP may include (i) the imaging of other high-energy single-photon emitters (e.g. I-131) and (ii) localized imaging of positron emitting tracers simultaneously with single photon emitters, with an even better resolution than coincidence PET.

  16. Optimised performance of industrial high resolution computerised tomography

    International Nuclear Information System (INIS)

    Maangaard, M.

    2000-01-01

    -sensitivity/noise, density-sensitivity/noise, and mass attenuation-sensitivity/noise. With these measures, a method is presented that finds the optimal equipment settings, where no improvement can be made without worsening at least one other sensitivity/noise ratio. This thesis includes modelling and verification of the sharpness of the CT system in terms of the modulation transfer function, MTF. Together with the limiting perception factor and the maximised SNR the detectability limits for any specific contrasting detail in the centre of a cylindrical sample can be determined. It is also demonstrated that the model can be used to suppress beam hardening when collecting CT-data. When homogeneous samples are imaged, the model can in addition be used to make post-processing corrections for suppressing the beam hardening artefacts. Wavelet-based local tomography has been found to produce images with good accuracy from projection data only from a small region in a sample. This technique is demonstrated on thermal barrier coatings, which contain internal cracks. With optimised equipment settings and geometrical magnification of a region in the sample, wavelet-based local tomography produced high-resolution images of excellent quality. The increased resolution reveals features in the microstructure that cannot be resolved with traditional CT. This technique will be a useful tool for characterisation of the microstructure in advanced materials

  17. Noninvasive Characterization of Indeterminate Pulmonary Nodules Detected on Chest High-Resolution Computed Tomography

    Science.gov (United States)

    2017-10-01

    Chest High- Resolution Computed Tomography 5b. GRANT NUMBER W81XWH-15-1-0110 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Fabien Maldonado 5d. PROJECT...Selection of cancer cases and controls, flowcharts : Screen-detected lung cancers (N=649) Adenocarcinomas (N=353) Squamous cell carcinomas (N=136...during the process, and I hope everyone has a nice weekend! Best, Liz …… Elizabeth S. Moses, Ph.D. | Scientific Program Manager, DECAMP Boston

  18. Tracking Solid Oxide Cell Microstructure Evolution by High Resolution 3D Nano-Tomography

    DEFF Research Database (Denmark)

    De Angelis, Salvatore

    . The degradation processes are mainly attributed to morphological changes occurring within the electrodes microstructure. Therefore, precise tracking of 3D microstructural evolution during operation is considered crucial to understanding the complex relationship between microstructure and performance. In this work......, X-ray ptychographic tomography is applied to SOC materials, demonstrating unprecedented spatial resolution and data quality. The eect of a complete redox cycle on the same Ni-YSZ microstructure is visualized ex-situ in 3D, showing major rearrangement of the nickel network after reduction......, the formation of cracks in the YSZ, and void formation in nickel oxide after oxidation. Capitalizing on the high resolution of ptychography, the eect of nickel coarsening on the Ni-YSZ microstructure evolution is studied ex-situ in three dimensions, while the sample is repeatedly scanned and treated at high...

  19. Computerized tomography and pulmonary diffusing capacity in highly trained athletes after performing a triathlon.

    Science.gov (United States)

    Caillaud, C; Serre-Cousiné, O; Anselme, F; Capdevilla, X; Préfaut, C

    1995-10-01

    We investigated the computerized tomographies (CTs) of the thorax and the pulmonary diffusing capacity for CO (DLCO) in eight male athletes before and after a triathlon. DLCO and alveolar volume (VA) were simultaneously measured during 9 s of breath holding. The transfer coefficient (KCO = DLCO/VA) was then calculated. CT scanning was performed during breath holding with the subjects in the supine position. Scanner analysis was done by 1) counting the linear and polygonal opacities (index of interstitial fluid accumulation) and 2) calculating the physical mean lung density and the mean slice mass. Results showed a significant reduction in DLCO (44.9 +/- 2.3 vs. 42.9 +/- 1.7 ml.min-1.mmHg-1; P triathlon and an increase in mean lung density (0.21 +/- 0.009 vs. 0.25 +/- 0.01 g/cm3; P long-distance race and showed a concomitant increase in CT lung density and in the number of opacities.

  20. Breast tumor segmentation in high resolution x-ray phase contrast analyzer based computed tomography.

    Science.gov (United States)

    Brun, E; Grandl, S; Sztrókay-Gaul, A; Barbone, G; Mittone, A; Gasilov, S; Bravin, A; Coan, P

    2014-11-01

    Phase contrast computed tomography has emerged as an imaging method, which is able to outperform present day clinical mammography in breast tumor visualization while maintaining an equivalent average dose. To this day, no segmentation technique takes into account the specificity of the phase contrast signal. In this study, the authors propose a new mathematical framework for human-guided breast tumor segmentation. This method has been applied to high-resolution images of excised human organs, each of several gigabytes. The authors present a segmentation procedure based on the viscous watershed transform and demonstrate the efficacy of this method on analyzer based phase contrast images. The segmentation of tumors inside two full human breasts is then shown as an example of this procedure's possible applications. A correct and precise identification of the tumor boundaries was obtained and confirmed by manual contouring performed independently by four experienced radiologists. The authors demonstrate that applying the watershed viscous transform allows them to perform the segmentation of tumors in high-resolution x-ray analyzer based phase contrast breast computed tomography images. Combining the additional information provided by the segmentation procedure with the already high definition of morphological details and tissue boundaries offered by phase contrast imaging techniques, will represent a valuable multistep procedure to be used in future medical diagnostic applications.

  1. Computerized mini-tomography scanner for X-ray and gamma-ray for multipurpose applications

    International Nuclear Information System (INIS)

    Cruvinel, P.E.

    1987-01-01

    The main results of this thesis is the development, implementation and use of an X-ray and γ-ray computerized minitomography scanner with possible applications in multidisciplinary fields particularly in soil physics. The hardware is basically a mechanical table with two step motors, one for rotation and another for translation motions, radioactive source, collimators, radiation detector with NaI(Tl) crystal, electronic pulse handling system and microcomputer with two floppy disk-units (5 1/4''), video with high resolution and graphic printer.(author)

  2. Some aspects of evaluation of image quality in computerized tomography

    International Nuclear Information System (INIS)

    Travassos, Paulo Cesar Baptista; Peixoto, Jose Guilherme; Almeida, Carlos Eduardo Veloso de; Campos, Luciana Tourinho; Magalhaes, Luis Alexandre

    2016-01-01

    The evaluation of CT scanners image quality includes measuring the Hounsfield values, HU, using a table with the limit values. This table does not consider that different devices have different effective energies, which may cause some false results. The evaluation of 90 computerized tomography, by the American College Radiology methodology, showed that some failed devices in the evaluation showed excellent linear fit between the values of the linear attenuation coefficients calculated for the actual energy used, according to the HU values. The analysis of the coefficient of determination suggests that 10 of these devices could have been approved. (author)

  3. Pulmonary paracoccidioidomycosis: A case report with high-resolution computed tomography findings

    Directory of Open Access Journals (Sweden)

    M. Armas

    2012-07-01

    Full Text Available Paracoccidioidomycosis is a systemic mycosis which is endemic in rural areas of Latin America, an important European source of immigrants and a growing European touristic destination as well, with most cases occurring in Brazil, Argentina, Venezuela and Colombia. The authors report a case of a 43-year-old man who previously worked in Venezuela and is living in Portugal for 8 years, presenting with a single cutaneous lesion. Despite the absence of valuable respiratory complaints, severe lung damage was found with high-resolution computed tomography (HRCT. Biopsy of the cutaneous lesion and mycologic sputum examination were performed revealing Paracoccidioides brasiliensis infection. Resumo: A Paracoccidioidomicose é uma micose sistémica endémica nas áreas rurais da América Latina, uma fonte importante de imigrantes e destino de emigração e turismo europeu, a maioria dos casos ocorrendo no Brasil, Argentina, Venezuela e Colômbia. Os autores descrevem o caso clínico de um paciente com 43 anos, anteriormente emigrado na Venezuela e residente em Portugal há 8 anos, que se apresenta com lesão cutânea isolada. Embora sem queixas relevantes do foro respiratório, apresentava extensas lesões do parênquima pulmonar caracterizadas por tomografia computorizada de alta resolução (TCAR. Foi realizada biópsia da lesão cutânea e exame micológico da expetoração que revelaram infeção por Paracoccidioides brasiliensis (PB. Keywords: Paracoccidioidomycosis, Paracoccidioides brasiliensis, Pulmonary fibrosis, High-resolution computed tomography, Palavras-chave: Paracoccidioidomicose, Paracoccidioides brasiliensis, Fibrose pulmonar, Tomografia computorizada de alta resolução

  4. A study with high resolution computed tomography of bone destruction in cholesteatoma

    International Nuclear Information System (INIS)

    Kikuchi, Shigeru; Yamaso, Tatsuya; Higo, Ryusaburo; Senba, Tetsuo; Iinuma, Yoshitaka.

    1992-01-01

    The modes and incidences of bone destruction in the middle ear cholesteatoma were evaluated by high resolution computed tomography, comparing with chronic otitis media with central perforation (COM) as control. The head of the malleus, the body and long process of the incus were more markedly destroyed in cholesteatoma than in COM with statistical significance. With the further extension of cholesteatoma into the antrum, the tegmen of the aditus ad antrum, the lateral semicircular canal, the handle of the malleus and the Korner's septum were involved in bone destruction. (author)

  5. Computerized tomography in the diagnosis of early and late complications after lung surgery

    International Nuclear Information System (INIS)

    Jeschke, W.; Linder, M.; Weiss, A.; Kihm, W.D.; Kempmann, G.

    1980-01-01

    The advantages of computerized tomography over conventional radiography for correctly interpreting doubtful findings after lung surgery are illustrated by 4 cases histories. In the immediate post-operative period the technique generally succeeds in identifying the nature of the abnormal findings and in differentiating between effusion, infiltration, abscess and empyema. Leakage from the bronchial stump can be clearly demonstrated without inconveniencing the patient. (orig.) [de

  6. Cone beam computerized tomography of face. Technological assessment report

    International Nuclear Information System (INIS)

    Saint-Pierre, Francoise; Fanelli, Gaelle; Mosnegutu, Lavinia; Devaux, Frederique

    2009-12-01

    Cone beam computerized tomography is an imagery technique notably used for the maxillofacial complex or a complete or limited exploration of maxillo-mandibular and dento-alveolar structures. Typically, this technique is implemented with devices which are different from scanners in various respects (performance of several linear cuts, use of an open cone beam). Based on a literature survey, this document reports an assessment which aimed at determining technical and dosimetric performances of the device, potential benefits in terms of diagnosis and therapy with respect to existing imagery techniques, specifications and role of this technique in odonto-stomatology, maxillofacial surgery, and even in ENT, and operation conditions and training to perform this act

  7. Computerized axial tomography in the detection of brain damage

    International Nuclear Information System (INIS)

    Cala, L.A.; Mastaglia, F.L.

    1980-01-01

    The cranial computerized axial tomography (CAT) findings in groups of patients with epilepsy, migraine, hypertension, and other general medical disorders have been reviewed to assess the frequency and patterns of focal and diffuse brain damage. In addition to demonstrating focal lesions in a proportion of patients with seizures and in patients presenting with a stroke, the CAT scan showed a premature degree of cerebral atrophy in an appreciable proportion of patients with long-standing epilepsy, hypertension and diabetes, and in some patients with migraine, valvular and ischaemic heart disease, chronic obstructive airways disease, and chronic renal failure. The value of CAT as a means of screening for brain damage in groups of individuals at risk is discussed

  8. The application of computerized tomography in the diagnosis of renal diseases

    International Nuclear Information System (INIS)

    Rzymski, K.

    1980-01-01

    The purpose of the report is presentation of the experiences collected in the diagnosis of renal changes obtained by means of computerized tomography after application of this method in 800 examinations of the abdominal cavity. In 88 cases the examination was performed because of diagnosed or supposed renal disease. The examination was done using an EMI Medical CT 5005/2 whole-body scanner. In the group of 88 cases in 22 unilateral or bilateral hydronephros was diagnosed, in 16 cases single cysts were demonstrated in the kidneys, in 5 polycystic renal disease, in 9 malignant neoplasms and in 11 nephrosclerosis were found. Besides that, atrophic kidneys were recognized and patients were examined after nepherctomy carried out for neoplasm. The final diagnosis was based on surgical, autopsy, angiographic and clinical findings. Computerized tomography of the kidneys is important mainly as a method supplementing traditional methods of examination of the kidneys. The main indication to the use of this method as the first radiological examination of the kidneys is in search for the cause of morphological renal failure, so called ''dumb kidney'' in urography, and in search for retroperitoneal metastases and recurrences after operations of renal neoplasms. In all other circumstances it should be accepted as a rule to begin renal examination with plain-film taking and intravenous urography, which methods together with other classic radiological methods make possible recognition of the causes of renal diseases in most cases. (author)

  9. Functional high-resolution computed tomography of pulmonary vascular and airway reactions

    International Nuclear Information System (INIS)

    Herold, C.J.; Johns Hopkins Medical Institutions, Baltimore, MD; Brown, R.H.; Johns Hopkins Medical Institutions, Baltimore, MD; Johns Hopkins Medical Institutions, Baltimore, MD; Wetzel, R.C.; Herold, S.M.; Zeerhouni, E.A.

    1993-01-01

    We describe the use of high-resolution computed tomography (HRCT) for assessment of the function of pulmonary vessels and airways. With its excellent spatial resolution, HRCT is able to demonstrate pulmonary structures as small as 300 μm and can be used to monitor changes following various stimuli. HRCT also provides information about structures smaller than 300 μm through measurement of parenchymal background density. To date, sequential, spiral and ultrafast HRCT techniques have been used in a variety of challenges to gather information about the anatomical correlates of traditional physiological measurements, thus making anatomical-physiological correlation possible. HRCT of bronchial reactivity can demonstrate the location and time course of aerosol-induced broncho-constriction and may show changes not apparent on spirometry. HRCT of the pulmonary vascular system visualized adaptations of vessels during hypoxia and intravascular volume loading and elucidates cardiorespiratory interactions. Experimental studies provide a basis for potential clinical applications of this method. (orig.) [de

  10. Intoxication for methyl alcohol: computerized tomography and finding in the necrosis

    International Nuclear Information System (INIS)

    Abaitua Ibanez, J.M.; Garcia Monco, J.C.; Gallardo Rebollan, S.; Hernando Aguado, G.; Alcaraz, R.; Lopez-Ruiz, J.A.

    1994-01-01

    We present a case of voluntary intake of methyl alcohol studied by means of computerized tomography (CT) in a previously healthy patient. The classical findings of bilateral putaminal necrosis are corroborated and cerebral white matter lesions are detected in frontal and occipital zones, signs that are unusual in this disorder. CT can be of diagnostic interest in certain comas of metabolic origin such as methanol intoxication, revealing antemortem lesions of both putamens and white matter. Finally, a correlation between the CT and necropsy findings is established. (Author) 11 refs

  11. High resolution computed tomography in patients with various forms of systemic sclerosis

    International Nuclear Information System (INIS)

    Lewszuk, A.; Rozycki, J.; Tarasow, E.; Kowal-Bielecka, O.

    2008-01-01

    Pulmonary lesions are, besides renal and cardiac complications, one of the main causes of mortality among patients with systemic sclerosis (scleroderma). Pathologic changes in the respiratory system take the form of interstitial fibrosis clinically manifested by progressive exertion dyspnea and abnormalities of respiratory restriction type in functional tests. The aim of the study was systematization of pulmonary lesion symptomatology in conventional chest radiography and high resolution computed tomography (HRCT) in patients with various forms of scleroderma, as well as determination of the frequency and localization of the particular lesion types. The study was carried out in a group of 49 patients with systemic sclerosis (47 women and 2 men), who underwent conventional radiography and high resolution computed tomography of the chest. In patients with systemic sclerosis, HRCT revealed most frequently interstitial changes of ground glass type, as well as linear and reticular opacities, whereas bronchiectasis and honeycombing type lesions were less frequent. Pulmonary lesions were seen with increasing frequency towards the lung base and were localized mainly in the posterior, inferior and peripheral parts of the lungs. Comparison of the patients with limited and diffuse scleroderma demonstrated that the diffuse form is associated with more frequent involvement of the respiratory system and more advanced pulmonary lesions. The observed characteristics of pulmonary lesions show similarity between interstitial lung disease in the course of systemic sclerosis and nonspecific interstitial pneumonia (NSIP), which supports classification of interstitial lung disease associated with scleroderma as belonging to that group of interstitial inflammations. (author)

  12. Breast tumor segmentation in high resolution x-ray phase contrast analyzer based computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    Brun, E., E-mail: emmanuel.brun@esrf.fr [European Synchrotron Radiation Facility (ESRF), Grenoble 380000, France and Department of Physics, Ludwig-Maximilians University, Garching 85748 (Germany); Grandl, S.; Sztrókay-Gaul, A.; Gasilov, S. [Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital Munich, 81377 Munich (Germany); Barbone, G. [Department of Physics, Harvard University, Cambridge, Massachusetts 02138 (United States); Mittone, A.; Coan, P. [Department of Physics, Ludwig-Maximilians University, Garching 85748, Germany and Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital Munich, 81377 Munich (Germany); Bravin, A. [European Synchrotron Radiation Facility (ESRF), Grenoble 380000 (France)

    2014-11-01

    Purpose: Phase contrast computed tomography has emerged as an imaging method, which is able to outperform present day clinical mammography in breast tumor visualization while maintaining an equivalent average dose. To this day, no segmentation technique takes into account the specificity of the phase contrast signal. In this study, the authors propose a new mathematical framework for human-guided breast tumor segmentation. This method has been applied to high-resolution images of excised human organs, each of several gigabytes. Methods: The authors present a segmentation procedure based on the viscous watershed transform and demonstrate the efficacy of this method on analyzer based phase contrast images. The segmentation of tumors inside two full human breasts is then shown as an example of this procedure’s possible applications. Results: A correct and precise identification of the tumor boundaries was obtained and confirmed by manual contouring performed independently by four experienced radiologists. Conclusions: The authors demonstrate that applying the watershed viscous transform allows them to perform the segmentation of tumors in high-resolution x-ray analyzer based phase contrast breast computed tomography images. Combining the additional information provided by the segmentation procedure with the already high definition of morphological details and tissue boundaries offered by phase contrast imaging techniques, will represent a valuable multistep procedure to be used in future medical diagnostic applications.

  13. Computerized tomography in diagnosis of parasitic hepatic lesions

    International Nuclear Information System (INIS)

    Filimonov, G.P.; Garibashvili, R.N.; Tumol'skaya, N.I.

    1984-01-01

    An attempt has been made to estimate the diagnostic importance of computerized tomography (CT) in cases of hepatic echinococcosis and alveococcosis to outline the semiotics of these lesions and to establish an order of using CT in a general diagnostic complex. 73 patients at the age of 15-70 (49 with echinococcosis, 24-alveococcosis) have been supervised. The analysis of the results of clinical CT application in cases of parasitic hepatic lesions has shown that CT permits not only to reveal parasitic nodes up to 2 cm size in the liver and other organs but give also their topographoanatomic characteristic. By means of CT one can determine interrelations of parasitic formation with vessels and hepatic bileducts, vena cava inferior, other organs. One can judge at the same time on their compression and germination, remote echinococcosis residues, other complications

  14. High-resolution computed tomography of cholesteatoma of the middle ear

    International Nuclear Information System (INIS)

    Ishii, Kiyoshi; Fukusumi, Akio; Okudera, Toshio; Kato, Toshihiko; Soda, Toyoji

    1988-01-01

    The high-resolution computed tomography (CT) appearances of 72 consecutive cases (92 ears) of chronic otomastoiditis were reviewed. The cholesteatomas were verified surgically and/or otologically in 35 of these 92 ears. Discussion was made with special emphasis on the differential diagnosis of cholesteatoma of the middle ear from the non-cholesteatoma otitis media. The CT findings suggestive of cholesteatoma were as follows: the definitive findings was of a soft-tissue opacity filling Purssak's space, with a medial displacement of the malleus and the incus; the possible findings were 1) a bony erosion of the wall of the middle ear cavity, 2) a partial or complete disappearance of the malleus and/or the incus, and 3) an opacification of Purssak's space and the superomedial aspect of the external auditory meatus. (author)

  15. Density evaluation by computerized tomography in plain soils over different manipulation systems; Avaliacao da densidade pelo metodo da tomografia computadorizada de um planossolo sob diferentes sistemas de manejo

    Energy Technology Data Exchange (ETDEWEB)

    Pedrotti, Alceu [Lavras Univ., MG (Brazil). Dept. de Ciencia do Solo; Pauletto, Eloy Antonio [Pelotas Univ., RS (Brazil). Dept. de Solos; Crestana, Silvio [Empresa Brasileira de Pesquisa Agropecuaria (EMBRAPA), Sao Carlos, SP (Brazil). Centro Nacional de Pesquisa e Desenvolvimento de Instrumentacao Agropecuaria (CNPDIA)

    1996-08-01

    The objective of this paper is the evaluation of a plain soil density in different culture systems determined by X ray computerized tomography.It was observed a larger variation in densities in soils profiles analysed. The identification of layers is better utilising computerized tomography than others technic 1 fig.

  16. Dose profile study on computerized tomography scanning of skull with simulator object

    International Nuclear Information System (INIS)

    Mourao, A.P.

    2011-01-01

    This work presents a comparison among the dose profiles in scanning of computerized tomography of a simulator object of PMMA in its periphery region. To obtain the deposited dose at the PMMA thermoluminescent dosemeters were used positioned at the interior of PMMA simulated object longitudinal to periphery and at the center of cylinder (positions denominated North, South, East, West and Center). Eight scanning were performed of simulator object using the routine protocol for skull in eight different services of radiodiagnostic by TC

  17. Computerized tomography

    International Nuclear Information System (INIS)

    1980-01-01

    Improvements in the design of computerized tomographic X-ray equipment are described which lead to improvements in the mechanical properties, speed and size of scanning areas. The method envisages the body being scanned as a two-dimensional matrix of elements arising from a plurality of concentric rings. The concentric centre need not coincide with the axis of rotation. The procedures for rotation of the X-ray beam and detectors around the patient and for translating the measured information into attenuation coefficients for each matrix element of the body are described in detail. Explicit derivations are given for the mathematical formulae used. (U.K.)

  18. Contribution of computerized tomography to diagnosis of congenital toxoplasmosis

    International Nuclear Information System (INIS)

    Kouba, K.; Kalvach, P.; Nevarilova, A.; Stankova, M.

    1986-01-01

    Computerized tomography (CT) of the brain in 20 patients (age 6 to 20 years) with the ocular form of toxoplasmosis and various damage of the CNS revealed that in 8 patients intracranial calcifications were present while no calcifications were found on the X-ray of the skull. On the CT also other pathological findings were detected in the brain apart from calcifications. (Similarly as in 25% of the AIDS syndrome where affections of the CNS are not yet known.) Based on the authors'experience and data from abroad, CT examination of the brain can be recommended as very useful for the confirmation of the diagnosis of congenital toxoplasmosis also with regard to the prognosis of further psychomotoric development of the child. (author). 2 tabs., 7 refs

  19. Motion Estimation and Compensation Strategies in Dynamic Computerized Tomography

    Science.gov (United States)

    Hahn, Bernadette N.

    2017-12-01

    A main challenge in computerized tomography consists in imaging moving objects. Temporal changes during the measuring process lead to inconsistent data sets, and applying standard reconstruction techniques causes motion artefacts which can severely impose a reliable diagnostics. Therefore, novel reconstruction techniques are required which compensate for the dynamic behavior. This article builds on recent results from a microlocal analysis of the dynamic setting, which enable us to formulate efficient analytic motion compensation algorithms for contour extraction. Since these methods require information about the dynamic behavior, we further introduce a motion estimation approach which determines parameters of affine and certain non-affine deformations directly from measured motion-corrupted Radon-data. Our methods are illustrated with numerical examples for both types of motion.

  20. Method of evaluation of diagnostics reference levels in computerized tomography; Metodo de avaliacao de niveis de referencia de radiodiagnostico em tomografia computadorizada

    Energy Technology Data Exchange (ETDEWEB)

    Vega, Walter Flores

    1999-04-01

    Computerized tomography is a complex technique with several selectable exposition parameters delivering high doses to the patient. In this work it was developed a simple methodology to evaluate diagnostic reference levels in computerized tomography, using the concept of Multiple Scan Average Dose (MSAD), recently adopted by the Health Ministry. For evaluation of the MSAD, a dose distribution was obtained through a measured dose profile on the axial axis of a water phantom with thermoluminescence dosemeters, TLD-100, for different exam technique. The MSAD was evaluated hrough two distinct methods. First, it was evaluated by the integration of the dose profile of a single slice and, second, obtained by the integration on central slice of the profile of several slices. The latter is in of accordance with the ionization chamber method, suggesting to be the most practical method of dose evaluation to be applied in the diagnostic reference level assessment routine for CT, using TLDs. (author)

  1. Computerized tomography of chest in emphysema and interstitial diseases diagnosis

    International Nuclear Information System (INIS)

    Souto Bayarri, M.; Malagari, K.; Ibarburen, C.; Arenas, G.; Correa Pombo, J.; Garcia Tahoces, P.; Tucker, D.; Barnes, G.T.; Luna, R.; Zerhouni, E.A.; Fraser, R.G.; Vidal Carrerira, J.J.

    1994-01-01

    To study the effect of increasing the spatial resolution on thin section (1.5 mm) computed tomography (CT) of the chest, we compared images reconstructed with the standard algorithm (SA) to three other images obtained with 1) a high spatial frequency algorithm, 2) retrospective targeting to a small field of view (FOV) reconstructed with the high spatial frequency algorithm, and 3) the same high spatial frequency algorithm with images acquired with the small (0.6 mm) rather the large (0.9 mm) focal spot. Examinations were performed on a phantom, on normal subjects, and on patients with emphysema and other diffuse lung diseases. Modulation transfer function (MTF) calculations revealed that higher resolution was achieved on the small focal spot and high spatial frequency algorithm than on the standard algorithm. Evaluation of the four images from 25 normal subjects, 16 patients with emphysema and 9 with interstitial disease was performed by means of an ROC study. Results from the areas under the ROC curves, sensitivity and specificity have shown that images reconstructed with the high spatial frequency algorithm were preferred. We conclude that the use of a high spatial frequency algorithm increases spatial resolution and improves visibility of lung parenchyma. Although more evaluation is needed, the potential of increasing spatial resolution further by using a smaller focal spot is currently limited by the mas Available per slice and the associated increased level of quantum noise. (Author)

  2. Quantitative image analysis of vertebral body architecture - improved diagnosis in osteoporosis based on high-resolution computed tomography

    International Nuclear Information System (INIS)

    Mundinger, A.; Wiesmeier, B.; Dinkel, E.; Helwig, A.; Beck, A.; Schulte Moenting, J.

    1993-01-01

    71 women, 64 post-menopausal, were examined by single-energy quantitative computed tomography (SEQCT) and by high-resolution computed tomography (HRCT) scans through the middle of lumbar vertebral bodies. Computer-assisted image analysis of the high-resolution images assessed trabecular morphometry of the vertebral spongiosa texture. Texture parameters differed in women with and without age-reduced bone density, and in the former group also in patients with and without vertebral fractures. Discriminating parameters were the total number, diameter and variance of trabecular and intertrabecular spaces as well as the trabecular surface (p < 0.05)). A texture index based on these statistically selected morphometric parameters identified a subgroup of patients suffering from fractures due to abnormal spongiosal architecture but with a bone mineral content not indicative for increased fracture risk. The combination of osteodensitometric and trabecular morphometry improves the diagnosis of osteoporosis and may contribute to the prediction of individual fracture risk. (author)

  3. Epiploic appendicitis and omental infarction. Findings in the ultrasonography and computerized tomography

    International Nuclear Information System (INIS)

    Migule, A.; Ripolles, T.; Martinez, M. J.; Morote, V.; Ruiz, A.

    2001-01-01

    Describe the findings in the ultrasonography and computerized tomography (CT) of the omental infarction and epiploic appendicitis. The clinical and radiological findings of the patients diagnosed in our hospital with epiploic appendicitis or omental infarctions between August 1994 and March 2001 were assessed retrospectively. We found a high incidence (42 cases) of these two diseases: 30 patients with diagnosis of epiploic appendicitis and 12 with the diagnosis of omental infarction. Four patients were treated surgically, while the remaining 38 were conservatively, without posterior complications. The ultrasonography and CT images is characteristics. making it possible to make a diagnosis of epiploic appendicitis or omental infarction with certainty. It is not necessary to make a differential diagnosis between the two entities because their prognosis and treatment are similar. Their incidence is much more frequent than that previously published. (Author) 19 refs

  4. Effective radiation dose of ProMax 3D cone-beam computerized tomography scanner with different dental protocols.

    Science.gov (United States)

    Qu, Xing-min; Li, Gang; Ludlow, John B; Zhang, Zu-yan; Ma, Xu-chen

    2010-12-01

    The aim of this study was to compare effective doses resulting from different scan protocols for cone-beam computerized tomography (CBCT) using International Commission on Radiological Protection (ICRP) 1990 and 2007 calculations of dose. Average tissue-absorbed dose, equivalent dose, and effective dose for a ProMax 3D CBCT with different dental protocols were calculated using thermoluminescent dosimeter chips in a human equivalent phantom. Effective doses were derived using ICRP 1990 and the superseding 2007 recommendations. Effective doses (ICRP 2007) for default patient sizes from small to large ranged from 102 to 298 μSv. The coefficient of determination (R(2)) between tube current and effective dose (ICRP 2007) was 0.90. When scanning with lower resolution settings, the effective doses were reduced significantly (P radiation dose levels. Reduction in radiation dose can be achieved when using lower settings of exposure parameters. Copyright © 2010 Mosby, Inc. All rights reserved.

  5. Extension of the Gladstone-Dale equation for flame flow field diagnosis by optical computerized tomography

    International Nuclear Information System (INIS)

    Chen Yunyun; Li Zhenhua; Song Yang; He Anzhi

    2009-01-01

    An extended model of the original Gladstone-Dale (G-D) equation is proposed for optical computerized tomography (OCT) diagnosis of flame flow fields. For the purpose of verifying the newly established model, propane combustion is used as a practical example for experiment, and moire deflection tomography is introduced with the probe wavelength 808 nm. The results indicate that the temperature based on the extended model is more accurate than that based on the original G-D equation. In a word, the extended model can be suitable for all kinds of flame flow fields whatever the components, temperature, and ionization are.

  6. High-resolution photoacoustic tomography of resting-state functional connectivity in the mouse brain

    Science.gov (United States)

    Nasiriavanaki, Mohammadreza; Xia, Jun; Wan, Hanlin; Bauer, Adam Quentin; Culver, Joseph P.; Wang, Lihong V.

    2014-01-01

    The increasing use of mouse models for human brain disease studies presents an emerging need for a new functional imaging modality. Using optical excitation and acoustic detection, we developed a functional connectivity photoacoustic tomography system, which allows noninvasive imaging of resting-state functional connectivity in the mouse brain, with a large field of view and a high spatial resolution. Bilateral correlations were observed in eight functional regions, including the olfactory bulb, limbic, parietal, somatosensory, retrosplenial, visual, motor, and temporal regions, as well as in several subregions. The borders and locations of these regions agreed well with the Paxinos mouse brain atlas. By subjecting the mouse to alternating hyperoxic and hypoxic conditions, strong and weak functional connectivities were observed, respectively. In addition to connectivity images, vascular images were simultaneously acquired. These studies show that functional connectivity photoacoustic tomography is a promising, noninvasive technique for functional imaging of the mouse brain. PMID:24367107

  7. Determination of the initial energy in computerized tomography with proton beams

    International Nuclear Information System (INIS)

    Rocha, Rodrigo Luis da

    2007-01-01

    In earliest works devoted to proton computed tomography it was shown that the advantage of pCT image reconstruction appears when the energy is close to the Bragg peak region, since the proton passes the object. This effect provided by the Bragg peak makes the computerized tomography with protons possible. However, when decreasing the initial proton energy, with the increase of the irradiation dose, there are two effects that work simultaneously in opposite ways. First, the energy loss of a proton in an object becomes bigger at small initial energy. At the same time decreasing of the proton energy results in the increase of the energy straggling, requiring a larger number of protons. In this work the radiation dose dependence on the proton initial energy was studied using analytical formulas and computer simulations. The investigation determined that the radiation dose practically does not depend on the initial energy, except in the energy region very close to the minimum energy necessary to pass the object. (author)

  8. Imaging of dopamine transporters in rats using high-resolution pinhole single-photon emission tomography

    Energy Technology Data Exchange (ETDEWEB)

    Booij, Jan; Bruin, Kora de; Habraken, Jan B.A. [Department of Nuclear Medicine, F2N, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam (Netherlands); Voorn, Pieter [Department of Anatomy, Vrije Universiteit Medical Center, Amsterdam (Netherlands)

    2002-09-01

    To date, the vast majority of investigations on the dopaminergic system in small animals have been in vitro studies. In comparison with in vitro studies, single-photon emission tomography (SPET) or positron emission tomography (PET) imaging of the dopaminergic system in small animals has the advantage of permitting repeated studies within the same group of animals. Dopamine transporter imaging is a valuable non-invasive tool with which to investigate the integrity of dopaminergic neurons. The purpose of this study was to investigate the feasibility of assessing dopamine transporter density semi-quantitatively in rats using a recently developed high-resolution pinhole SPET system. This system was built exclusively for imaging of small animals. In this unique single-pinhole system, the animal rotates instead of the collimated detector. The system has proven to have a high spatial resolution. We performed SPET imaging with [{sup 123}I]FP-CIT to quantify striatal dopamine transporters in rat brain. In all seven studied control rats, symmetrical striatal binding to dopamine transporters was seen 2 h after injection of the radiotracer, with striatal-to-cerebellar binding ratios of approximately 3.5. In addition, test/retest variability of the striatal-to-cerebellar binding ratios was studied and found to be 14.5%. Finally, in unilaterally 6-hydroxydopamine-lesioned rats, striatal binding was only visible on the non-lesioned side. Quantitative analysis revealed that striatal-to-cerebellar SPET ratios were significantly lower on the lesioned (mean binding ratio 2.2{+-}0.2) than on the non-lesioned (mean ratio 3.1{+-}0.4) side. The preliminary results of this study indicate that semi-quantitative assessment of striatal dopamine transporter density using our recently developed high-resolution single-pinhole SPET system is feasible in living rat brain. (orig.)

  9. Improvements in high energy computed tomography

    International Nuclear Information System (INIS)

    Burstein, P.; Krieger, A.; Annis, M.

    1984-01-01

    In computerized axial tomography employed with large relatively dense objects such as a solid fuel rocket engine, using high energy x-rays, such as a 15 MeV source, a collimator is employed with an acceptance angle substantially less than 1 0 , in a preferred embodiment 7 minutes of a degree. In a preferred embodiment, the collimator may be located between the object and the detector, although in other embodiments, a pre-collimator may also be used, that is between the x-ray source and the object being illuminated. (author)

  10. Prospects of linear reconstruction in atomic resolution electron holographic tomography

    International Nuclear Information System (INIS)

    Krehl, Jonas; Lubk, Axel

    2015-01-01

    Tomography commonly requires a linear relation between the measured signal and the underlying specimen property; for Electron Holographic Tomography this is given by the Phase Grating Approximation (PGA). While largely valid at medium resolution, discrepancies arise at high resolution imaging conditions. We set out to investigate the artefacts that are produced if the reconstruction still assumes the PGA even with an atomic resolution tilt series. To forego experimental difficulties the holographic tilt series was simulated. The reconstructed electric potential clearly shows peaks at the positions of the atoms. These peaks have characterisitic deformations, which can be traced back to the defocus a particular atom has in the holograms of the tilt series. Exchanging an atom for one of a different atomic number results in a significant change in the reconstructed potential that is well contained within the atom's peak. - Highlights: • We simulate a holographic tilt series of a nanocrystal with atomic resolution. • Using PGA-based Holographic Tomography we reconstruct the atomic structure. • The reconstruction shows characteristic artefacts, chiefly caused by defocus. • Changing one atom's Z produces a well localised in the reconstruction

  11. Prospects of linear reconstruction in atomic resolution electron holographic tomography

    Energy Technology Data Exchange (ETDEWEB)

    Krehl, Jonas, E-mail: Jonas.Krehl@triebenberg.de; Lubk, Axel

    2015-03-15

    Tomography commonly requires a linear relation between the measured signal and the underlying specimen property; for Electron Holographic Tomography this is given by the Phase Grating Approximation (PGA). While largely valid at medium resolution, discrepancies arise at high resolution imaging conditions. We set out to investigate the artefacts that are produced if the reconstruction still assumes the PGA even with an atomic resolution tilt series. To forego experimental difficulties the holographic tilt series was simulated. The reconstructed electric potential clearly shows peaks at the positions of the atoms. These peaks have characterisitic deformations, which can be traced back to the defocus a particular atom has in the holograms of the tilt series. Exchanging an atom for one of a different atomic number results in a significant change in the reconstructed potential that is well contained within the atom's peak. - Highlights: • We simulate a holographic tilt series of a nanocrystal with atomic resolution. • Using PGA-based Holographic Tomography we reconstruct the atomic structure. • The reconstruction shows characteristic artefacts, chiefly caused by defocus. • Changing one atom's Z produces a well localised in the reconstruction.

  12. Submicron Resolution Spectral-Domain Optical Coherence Tomography

    KAUST Repository

    Alarousu, Erkki; Jabbour, Ghassan

    2013-01-01

    Apparatuses and systems for submicron resolution spectral-domain optical coherence tomography (OCT) are disclosed. The system may use white light sources having wavelengths within 400-1000 nanometers, and achieve resolution below 1 .mu

  13. Use of a YAP:Ce matrix coupled to a position-sensitive photomultiplier for high resolution positron emission tomography

    International Nuclear Information System (INIS)

    Del Guerra, A.; Zavattini, G.; Notaristefani, F. de; Giganti, M.; Piffanelli, A.; Pani, R.; Turra, A.

    1996-01-01

    A new scintillation detector system has been designed for application in high resolution Positron Emission Tomography (PET). The detector is a bundle of small YAlO 3 :Ce (YAP) crystals closely packed (0.2 x 0.2 x 3.0 cm 3 ), coupled to a position sensitive photomultiplier tube (PSPMT). The preliminary results obtained for spatial resolution, time resolution, energy resolution and efficiency of two such detectors working in coincidence are presented. These are 1.2 mm for the FWHM spatial resolution, 2.0 ns for the FWHM time resolution and 20% for the FWHM energy resolution at 511 keV. The measured efficiency is (44 ± 3)% with a 150 keV threshold and (20 ± 2)% with a 300 keV threshold

  14. Computed Tomography Status

    Science.gov (United States)

    Hansche, B. D.

    1983-01-01

    Computed tomography (CT) is a relatively new radiographic technique which has become widely used in the medical field, where it is better known as computerized axial tomographic (CAT) scanning. This technique is also being adopted by the industrial radiographic community, although the greater range of densities, variation in samples sizes, plus possible requirement for finer resolution make it difficult to duplicate the excellent results that the medical scanners have achieved.

  15. VARIABILITY OF MANUAL AND COMPUTERIZED METHODS FOR MEASURING CORONAL VERTEBRAL INCLINATION IN COMPUTED TOMOGRAPHY IMAGES

    Directory of Open Access Journals (Sweden)

    Tomaž Vrtovec

    2015-06-01

    Full Text Available Objective measurement of coronal vertebral inclination (CVI is of significant importance for evaluating spinal deformities in the coronal plane. The purpose of this study is to systematically analyze and compare manual and computerized measurements of CVI in cross-sectional and volumetric computed tomography (CT images. Three observers independently measured CVI in 14 CT images of normal and 14 CT images of scoliotic vertebrae by using six manual and two computerized measurements. Manual measurements were obtained in coronal cross-sections by manually identifying the vertebral body corners, which served to measure CVI according to the superior and inferior tangents, left and right tangents, and mid-endplate and mid-wall lines. Computerized measurements were obtained in two dimensions (2D and in three dimensions (3D by manually initializing an automated method in vertebral centroids and then searching for the planes of maximal symmetry of vertebral anatomical structures. The mid-endplate lines were the most reproducible and reliable manual measurements (intra- and inter-observer variability of 0.7° and 1.2° standard deviation, SD, respectively. The computerized measurements in 3D were more reproducible and reliable (intra- and inter-observer variability of 0.5° and 0.7° SD, respectively, but were most consistent with the mid-wall lines (2.0° SD and 1.4° mean absolute difference. The manual CVI measurements based on mid-endplate lines and the computerized CVI measurements in 3D resulted in the lowest intra-observer and inter-observer variability, however, computerized CVI measurements reduce observer interaction.

  16. Ultrasonic computerized tomography (CT) for temperature measurements with limited projection data based on extrapolated filtered back projection (FBP) method

    International Nuclear Information System (INIS)

    Zhu Ning; Jiang Yong; Kato, Seizo

    2005-01-01

    This study uses ultrasound in combination with tomography to obtain three-dimensional temperature measurements using projection data obtained from limited projection angle. The main feature of the new computerized tomography (CT) reconstruction algorithm is to employ extrapolation scheme to make up for the incomplete projection data, it is based on the conventional filtered back projection (FBP) method while on top of that taking into account the correlation between the projection data and Fourier transform-based extrapolation. Computer simulation is conducted to verify the above algorithm. An experimental 3D temperature distribution measurement is also carried out to validate the proposed algorithm. The simulation and experimental results demonstrate that the extrapolated FBP CT algorithm is highly effective in dealing with projection data from limited projection angle

  17. Analysis of risk in computerized tomography and other diagnostic radiology procedures

    International Nuclear Information System (INIS)

    Mossman, K.L.

    1982-01-01

    Medical practice entails continuous risks to the patient taken in good faith by the physician for the benefit of the patient. Risk of radiation induced cancer death approximates 10(-4) per cGy (rad). Assuming an average whole body dose of 0.1 cGy for many diagnostic X-ray procedures, the probability of radiation-induced cancer death is about 10(-5). The purpose of this paper is to compare the risks of common diagnostic X-ray procedures including computerized tomography (CT) with risks of smoking or automobile travel. Such comparisons should be constructive in putting radiation in perspective and facilitating explanation of risk/benefit to patients

  18. Preliminary frequency-domain analysis for the reconstructed spatial resolution of muon tomography

    Science.gov (United States)

    Yu, B.; Zhao, Z.; Wang, X.; Wang, Y.; Wu, D.; Zeng, Z.; Zeng, M.; Yi, H.; Luo, Z.; Yue, X.; Cheng, J.

    2014-11-01

    Muon tomography is an advanced technology to non-destructively detect high atomic number materials. It exploits the multiple Coulomb scattering information of muon to reconstruct the scattering density image of the traversed object. Because of the statistics of muon scattering, the measurement error of system and the data incompleteness, the reconstruction is always accompanied with a certain level of interference, which will influence the reconstructed spatial resolution. While statistical noises can be reduced by extending the measuring time, system parameters determine the ultimate spatial resolution that one system can reach. In this paper, an effective frequency-domain model is proposed to analyze the reconstructed spatial resolution of muon tomography. The proposed method modifies the resolution analysis in conventional computed tomography (CT) to fit the different imaging mechanism in muon scattering tomography. The measured scattering information is described in frequency domain, then a relationship between the measurements and the original image is proposed in Fourier domain, which is named as "Muon Central Slice Theorem". Furthermore, a preliminary analytical expression of the ultimate reconstructed spatial is derived, and the simulations are performed for validation. While the method is able to predict the ultimate spatial resolution of a given system, it can also be utilized for the optimization of system design and construction.

  19. Preliminary frequency-domain analysis for the reconstructed spatial resolution of muon tomography

    International Nuclear Information System (INIS)

    Yu, B.; Zhao, Z.; Wang, X.; Wang, Y.; Wu, D.; Zeng, Z.; Zeng, M.; Yi, H.; Luo, Z.; Yue, X.; Cheng, J.

    2014-01-01

    Muon tomography is an advanced technology to non-destructively detect high atomic number materials. It exploits the multiple Coulomb scattering information of muon to reconstruct the scattering density image of the traversed object. Because of the statistics of muon scattering, the measurement error of system and the data incompleteness, the reconstruction is always accompanied with a certain level of interference, which will influence the reconstructed spatial resolution. While statistical noises can be reduced by extending the measuring time, system parameters determine the ultimate spatial resolution that one system can reach. In this paper, an effective frequency-domain model is proposed to analyze the reconstructed spatial resolution of muon tomography. The proposed method modifies the resolution analysis in conventional computed tomography (CT) to fit the different imaging mechanism in muon scattering tomography. The measured scattering information is described in frequency domain, then a relationship between the measurements and the original image is proposed in Fourier domain, which is named as M uon Central Slice Theorem . Furthermore, a preliminary analytical expression of the ultimate reconstructed spatial is derived, and the simulations are performed for validation. While the method is able to predict the ultimate spatial resolution of a given system, it can also be utilized for the optimization of system design and construction

  20. A numerical solution of the equation of the computerized tomography and its application in astrophysics

    International Nuclear Information System (INIS)

    Krastev, A.; Nedialkov, J.

    1983-01-01

    A method for numerical solving the equation of the computerized tomography is proposed. The method, is based on the Cormack's formulae and is applied for studying media with central symmetry. The generalization for the nonsymmetric case does not lead to complications. The method is applied for the investigation of the density distribution of the Earth, the other planets and the Sun by means of neutrino experiments

  1. Importance of computerized tomography for surgical treatment of intracranial hematomas

    International Nuclear Information System (INIS)

    Diemath, H.E.

    1982-01-01

    The improved treatment by using computerized tomography (CT) located operating theater and intensive care unit is reported in comparison of 3,382 patients with severe head injuries. By preoperative use of CT the frequency of diagnosed hermatomas was about the same (29.5% before CT; 27.0% with CT) but the preoperative diagnosed multiple hematomas were much more frequent (14.0% resp. 27.0%). The most important advantage however is the saving of time by CT in this localisation by which the chance of survival has increased from 54% to 69%. Without any doubt everywhere in neurotraumatology the CT should be situated as near as possible to the intensive care unit and to the operating theater and should be available 24 hours a day. (Author) [de

  2. Intrathoracic manifestations of collagen vascular diseases on high-resolution chest computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    Silva, C. Isabela S. [University of British Columbia, Vancouver (Canada). Vancouver General Hospital]. E-mail: isabela.silva@vch.ca; Mueller, Nestor L. [University of British Columbia, Vancouver (Canada). Vancouver General Hospital. Dept. of Radiology

    2008-05-15

    Intrathoracic manifestations of collagen vascular diseases are very common. The frequency of intrathoracic manifestations and the patterns of abnormality are variable depending on the type of collagen vascular disease and may simultaneously involve one or more of the following: lung parenchyma, airways, pulmonary vessels, pericardium, and pleura. The most common pulmonary manifestations are diffuse interstitial pneumonia and pulmonary hypertension which together represent the main causes of morbidity and mortality of these patients. Pulmonary, airway and pleural involvement may also be secondary to the disease therapy, or result from bacterial pneumonia or opportunistic infection. In the present review, the authors summarize the main intrathoracic manifestations of collagen vascular diseases and the differential diagnosis on high-resolution chest computed tomography. (author)

  3. Detection of drugs and explosives using neutron computerized tomography and artificial intelligence techniques

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, F.J.O. [Instituto de Engenharia Nuclear, Cidade Universitaria, Rio de Janeiro, CEP 21945-970, Caixa Postal 68550 (Brazil)], E-mail: fferreira@ien.gov.br; Crispim, V.R.; Silva, A.X. [DNC/Poli, PEN COPPE CT, UFRJ Universidade Federal do Rio de Janeiro, CEP 21941-972, Caixa Postal 68509, Rio de Janeiro (Brazil)

    2010-06-15

    In this study the development of a methodology to detect illicit drugs and plastic explosives is described with the objective of being applied in the realm of public security. For this end, non-destructive assay with neutrons was used and the technique applied was the real time neutron radiography together with computerized tomography. The system is endowed with automatic responses based upon the application of an artificial intelligence technique. In previous tests using real samples, the system proved capable of identifying 97% of the inspected materials.

  4. Detection of drugs and explosives using neutron computerized tomography and artificial intelligence techniques

    International Nuclear Information System (INIS)

    Ferreira, F.J.O.; Crispim, V.R.; Silva, A.X.

    2010-01-01

    In this study the development of a methodology to detect illicit drugs and plastic explosives is described with the objective of being applied in the realm of public security. For this end, non-destructive assay with neutrons was used and the technique applied was the real time neutron radiography together with computerized tomography. The system is endowed with automatic responses based upon the application of an artificial intelligence technique. In previous tests using real samples, the system proved capable of identifying 97% of the inspected materials.

  5. High resolution propagation-based imaging system for in vivo dynamic computed tomography of lungs in small animals

    Science.gov (United States)

    Preissner, M.; Murrie, R. P.; Pinar, I.; Werdiger, F.; Carnibella, R. P.; Zosky, G. R.; Fouras, A.; Dubsky, S.

    2018-04-01

    We have developed an x-ray imaging system for in vivo four-dimensional computed tomography (4DCT) of small animals for pre-clinical lung investigations. Our customized laboratory facility is capable of high resolution in vivo imaging at high frame rates. Characterization using phantoms demonstrate a spatial resolution of slightly below 50 μm at imaging rates of 30 Hz, and the ability to quantify material density differences of at least 3%. We benchmark our system against existing small animal pre-clinical CT scanners using a quality factor that combines spatial resolution, image noise, dose and scan time. In vivo 4DCT images obtained on our system demonstrate resolution of important features such as blood vessels and small airways, of which the smallest discernible were measured as 55–60 μm in cross section. Quantitative analysis of the images demonstrate regional differences in ventilation between injured and healthy lungs.

  6. Improved algorithm for computerized detection and quantification of pulmonary emphysema at high-resolution computed tomography (HRCT)

    Science.gov (United States)

    Tylen, Ulf; Friman, Ola; Borga, Magnus; Angelhed, Jan-Erik

    2001-05-01

    Emphysema is characterized by destruction of lung tissue with development of small or large holes within the lung. These areas will have Hounsfield values (HU) approaching -1000. It is possible to detect and quantificate such areas using simple density mask technique. The edge enhancement reconstruction algorithm, gravity and motion of the heart and vessels during scanning causes artefacts, however. The purpose of our work was to construct an algorithm that detects such image artefacts and corrects them. The first step is to apply inverse filtering to the image removing much of the effect of the edge enhancement reconstruction algorithm. The next step implies computation of the antero-posterior density gradient caused by gravity and correction for that. Motion artefacts are in a third step corrected for by use of normalized averaging, thresholding and region growing. Twenty healthy volunteers were investigated, 10 with slight emphysema and 10 without. Using simple density mask technique it was not possible to separate persons with disease from those without. Our algorithm improved separation of the two groups considerably. Our algorithm needs further refinement, but may form a basis for further development of methods for computerized diagnosis and quantification of emphysema by HRCT.

  7. Pathogenesis of traumatic intracerebral hematoma with a sequential study of computerized tomography

    Energy Technology Data Exchange (ETDEWEB)

    Ohmori, H; Miyazaki, S; Munekata, K; Fukushima, H [Hitachi General Hospital, Hitachi, Ibaraki (Japan); Shohji, A

    1981-04-01

    A sequential study with computerized tomography (CT scan) of two cases of traumatic intracerebral hematoma is reported. Case 1 was a 69-year-old man who had a head injury. The initial CT scan, taken 1 hour after his injury, showed a left temporal salt-and-pepper appearance, which proved to be a cerebral contusion. The CT scan 4.5 hours after his injury showed a left temporal high density area instead. An operation was performed, and a massive intracerebral hematoma was observed. Case 2 was a 61-year-old man who was also admitted because of a head injury. The initial CT scan, taken 1 hour after his injury, revealed several bifrontal intracerebral hemorrhagic spots in the low-density areas, suggesting contusion. A secondary CT scan (23 hours) demonstrated that the traumatic intracerebral hematoma had developed into a posttraumatic cerebral contusion. The operation disclosed a hematoma surrounded by contusion. These cases prove that traumatic intracerebral hematoma is often caused by cerebral contusion.

  8. Effect of quantization and interpolation of projections on the sensitivity of computerized tomography

    International Nuclear Information System (INIS)

    Vajnberg, Eh.I.; Fajngojz, M.L.

    1984-01-01

    The sources and forms of manifestation of errors in quantization and interpolation of projections in case of X-ray computerized tomography are considered and quantitative criteria of their evaluation are formulated. The dominating role of the interaction of two successive quantizations of projections - one-dimensional and two-dimensional ones is revealed. The necessity of joint optimization of the two-dimensional quantization range, expansion and form of interpolation function, quantized convolution nucleus is substantiated. The experimental results at aspect ratio of tomograms 256x256 and 480 projections are presented

  9. Computed tomography with selectable image resolution

    International Nuclear Information System (INIS)

    Dibianca, F.A.; Dallapiazza, D.G.

    1981-01-01

    A computed tomography system x-ray detector has a central group of half-width detector elements and groups of full-width elements on each side of the central group. To obtain x-ray attenuation data for whole body layers, the half-width elements are switched effectively into paralleled pairs so all elements act like full-width elements and an image of normal resolution is obtained. For narrower head layers, the elements in the central group are used as half-width elements so resolution which is twice as great as normal is obtained. The central group is also used in the half-width mode and the outside groups are used in the full-width mode to obtain a high resolution image of a body zone within a full body layer. In one embodiment data signals from the detector are switched by electronic multiplexing and in another embodiment a processor chooses the signals for the various kinds of images that are to be reconstructed. (author)

  10. Study on forefoot by computerized tomography

    Energy Technology Data Exchange (ETDEWEB)

    Machida, Eiichi (Nihon Univ., Tokyo. School of Medicine)

    1983-10-01

    Computerized tomography (CT) was used to study coronary sections of the forefoot in both normal and abnormal human feet. CT images of the transverse arches at the metatarsal head, middle and base of the shaft were classified into five patterns. In the pattern most commonly found in normal feet, the second metatarsus appeared elevated above the other metatarsal bones at all points, and there was a gradual and even reduction in elevation from the second to the fifth metatarsal. In cases of hallux valgus, however, a variety of deformities were noted in the arc of the second to fifth metatarsals, particularly at the head. The rotation of the first metatarsus and shift of the sesamoids were measured from CT images at the head of the first metatarsus. In hallux valgus, both the rotation and the sesamoid shift appeared to have a wider angle than in the case of normal feet. In normal feet, the differences between the rotation of the first metatarsus and shift of the sesamoids were relatively small, whereas in hallux valgus there was a much greater degree of variation. Furthermore, while normal feet the variation in rotation of the first metatarsus and sesamoid shift both tended to be either great or small, in hallux valgus a large degree of sesamoid shift was sometimes found in combination with a small degree of rotation of the first metatarsus.

  11. Study on forefoot by computerized tomography

    International Nuclear Information System (INIS)

    Machida, Eiichi

    1983-01-01

    Computerized tomography (CT) was used to study coronary sections of the forefoot in both normal and abnormal human feet. CT images of the transverse arches at the metatarsal head, middle and base of the shaft were classified into five patterns. In the pattern most commonly found in normal feet, the second metatarsus appeared elevated above the other metatarsal bones at all points, and there was a gradual and even reduction in elevation from the second to the fifth metatarsal. In cases of hallux valgus, however, a variety of deformities were noted in the arc of the second to fifth metatarsals, particularly at the head. The rotation of the first metatarsus and shift of the sesamoids were measured from CT images at the head of the first metatarsus. In hallux valgus, both the rotation and the sesamoid shift appeared to have a wider angle than in the case of normal feet. In normal feet, the differences between the rotation of the first metatarsus and shift of the sesamoids were relatively small, whereas in hallux valgus there was a much greater degree of variation. Furthermore, while normal feet the variation in rotation of the first metatarsus and sesamoid shift both tended to be either great or small, in hallux valgus a large degree of sesamoid shift was sometimes found in combination with a small degree of rotatin of the first metatarsus. (author)

  12. Computerized tomography magnified bone windows are superior to standard soft tissue windows for accurate measurement of stone size: an in vitro and clinical study.

    Science.gov (United States)

    Eisner, Brian H; Kambadakone, Avinash; Monga, Manoj; Anderson, James K; Thoreson, Andrew A; Lee, Hang; Dretler, Stephen P; Sahani, Dushyant V

    2009-04-01

    We determined the most accurate method of measuring urinary stones on computerized tomography. For the in vitro portion of the study 24 calculi, including 12 calcium oxalate monohydrate and 12 uric acid stones, that had been previously collected at our clinic were measured manually with hand calipers as the gold standard measurement. The calculi were then embedded into human kidney-sized potatoes and scanned using 64-slice multidetector computerized tomography. Computerized tomography measurements were performed at 4 window settings, including standard soft tissue windows (window width-320 and window length-50), standard bone windows (window width-1120 and window length-300), 5.13x magnified soft tissue windows and 5.13x magnified bone windows. Maximum stone dimensions were recorded. For the in vivo portion of the study 41 patients with distal ureteral stones who underwent noncontrast computerized tomography and subsequently spontaneously passed the stones were analyzed. All analyzed stones were 100% calcium oxalate monohydrate or mixed, calcium based stones. Stones were prospectively collected at the clinic and the largest diameter was measured with digital calipers as the gold standard. This was compared to computerized tomography measurements using 4.0x magnified soft tissue windows and 4.0x magnified bone windows. Statistical comparisons were performed using Pearson's correlation and paired t test. In the in vitro portion of the study the most accurate measurements were obtained using 5.13x magnified bone windows with a mean 0.13 mm difference from caliper measurement (p = 0.6). Measurements performed in the soft tissue window with and without magnification, and in the bone window without magnification were significantly different from hand caliper measurements (mean difference 1.2, 1.9 and 1.4 mm, p = 0.003, window settings with magnification. For uric acid calculi the measurement error was observed only in standard soft tissue window settings. In vivo 4.0x

  13. Materials testing by computerized tomography with neutrons and gamma-rays

    Energy Technology Data Exchange (ETDEWEB)

    El-Ghobary, A M; Bakkoush, F A; Megahid, R M [Reactor and Neutron Physics Department, Nuclear Research Center, A.E.A., Cairo (Egypt)

    1997-12-31

    The method of computerized tomography by fast neutrons and gamma-rays are used for inspecting and testing of materials by non-destructive technique. The transmission technique was applied using narrow collimated beams of reactor neutrons and gamma-ray. The neutron and gamma-rays transmitted through the object inspection were measured by means of a neutron gamma detector with Ne - 213 liquid organic scintillator. The undesired pulses of neutrons or gamma-rays are rejected from the transmitted beam by a discrimination technique based on the difference in the decay part of light pulse produced by recoil electrons or recoil protons. The transmitted neutrons or gamma-rays for different projections used to get the image of the section through the object investigated using the method of filtered back projection (FBP) algorithm. 8 figs.

  14. Detector response restoration in image reconstruction of high resolution positron emission tomography

    International Nuclear Information System (INIS)

    Liang, Z.

    1994-01-01

    A mathematical method was studied to model the detector response of high spatial-resolution positron emission tomography systems consisting of close-packed small crystals, and to restore the resolution deteriorated due to crystal penetration and/or nonuniform sampling across the field-of-view (FOV). The simulated detector system had 600 bismuth germanate crystals of 3.14 mm width and 30 mm length packed on a single ring of 60 cm diameter. The space between crystal was filled up with lead. Each crystal was in coincidence with 200 opposite crystals so that the FOV had a radius of 30 cm. The detector response was modeled based on the attenuating properties of the crystals and the septa, as well as the geometry of the detector system. The modeled detector-response function was used to restore the projections from the sinogram of the ring-detector system. The restored projections had a uniform sampling of 1.57 mm across the FOV. The crystal penetration and/or the nonuniform sampling were compensated in the projections. A penalized maximum-likelihood algorithm was employed to accomplish the restoration. The restored projections were then filtered and backprojected to reconstruct the image. A chest phantom with a few small circular ''cold'' objects located at the center and near the periphery of FOV was computer generated and used to test the restoration. The reconstructed images from the restored projections demonstrated resolution improvement off the FOV center, while preserving the resolution near the center

  15. Can carotid stenosis be operated without arteriography? Contribution of magnetic resonance and helical computerized tomography angiography

    International Nuclear Information System (INIS)

    Auffrau-Calvier, E.; Kersaint-Gilly, A. de; Desal, H.A.; Viarouge, M.P.; Havet, T.

    1996-01-01

    The aim of this work is to ascertain the role of the magnetic resonance angiography (MRA) and to compare it with the Doppler effect, the X-ray angiography and the new method of helical computerized tomography. Seventy one carotid bifurcations in 37 patients with suspected cerebral vascular events has been evaluated with the MRA and digitalized angiography, the reference method. The obtained data corroborate the good results proposed by other authors reporting in the literature and allow to propose this examination as a new means of investigating carotid bifurcations. Work with the helical computerized tomography appears to be promising too but there are few reported series. Therefore, there appears to be two interesting points: the reliability of distinguishing between very severe stenosis and occlusion, and the fine-tuned analysis of the plaque with detection of ulcerations. When a consistent approach is used to the evaluation of the carotid bifurcation, the Willis circle and the cerebral parenchyma, the MRA can complete the Doppler echo data and the preoperative arteriography can only be used in patients when the MRA and the Doppler echo results disagree. (authors)

  16. Renal calyceal anatomy characterization with 3-dimensional in vivo computerized tomography imaging.

    Science.gov (United States)

    Miller, Joe; Durack, Jeremy C; Sorensen, Mathew D; Wang, James H; Stoller, Marshall L

    2013-02-01

    Calyceal selection for percutaneous renal access is critical for safe, effective performance of percutaneous nephrolithotomy. Available anatomical evidence is contradictory and incomplete. We present detailed renal calyceal anatomy obtained from in vivo 3-dimentional computerized tomography renderings. A total of 60 computerized tomography urograms were randomly selected. The renal collecting system was isolated and 3-dimensional renderings were constructed. The primary plane of each calyceal group of 100 kidneys was determined. A coronal maximum intensity projection was used for simulated percutaneous access. The most inferior calyx was designated calyx 1. Moving superiorly, the subsequent calyces were designated calyx 2 and, when present, calyx 3. The surface rendering was rotated to assess the primary plane of the calyceal group and the orientation of the select calyx. The primary plane of the upper pole calyceal group was mediolateral in 95% of kidneys and the primary plane of the lower pole calyceal group was anteroposterior in 95%. Calyx 2 was chosen in 90 of 97 simulations and it was appropriate in 92%. Calyx 3 was chosen in 7 simulations but it was appropriate in only 57%. Calyx 1 was not selected in any simulation and it was anteriorly oriented in 75% of kidneys. Appropriate lower pole calyceal access can be reliably accomplished with an understanding of the anatomical relationship between individual calyceal orientation and the primary plane of the calyceal group. Calyx 2 is most often appropriate for accessing the anteroposterior primary plane of the lower pole. Calyx 1 is most commonly oriented anterior. Copyright © 2013 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

  17. Evaluation of the normal thoracic and abdominal aorta diameters by computerized tomography

    International Nuclear Information System (INIS)

    Lucarelli, Claudio Luiz

    1995-01-01

    The study was undertaken to evaluate, through computerized tomography, the diameters of the normal thoracic and abdominal aorta, as well as they are connected to gender, age and body surface area; and the ratio between measurements obtained at the ascending and descending limbs of the thoracic aorta, and between the abdominal aortic diameters. For that reason, we measured the widest anteroposterior diameters of the thoracic aortas at the levels of the arch, the root, the pulmonary artery, and the thoracic-abdominal transition, as well as the level of the emergence of the superior mesenteric artery, of the renal hila and just cephalad to the bifurcation of the abdominal aortas of 350 patients without cardiovascular diseases who had undergone computerized tomography of the thorax and/or abdomen for any other reasons. Observation and statistic analyses led us to conclude that: 1) both the thoracic and abdominal aortic diameters are reduced from their proximal to their distal portions; 2) the body surface influences the size of the aorta, although only extreme variations alter the vessel's caliber; 3) vessel diameter was observed to gradually increase with age; 4) men were found to have larger diameters than age matched women; 5) the ratio between the ascending and descending aortic diameters varies according to gender and age; 6) the relations between abdominal aortic diameters measured at the level of renal hila and cephalad to the bifurcation are independent from gender and age. But the relation between those measured at the level of the superior mesenteric artery and cephalad to the bifurcation are linked to gender, but not to age. (author)

  18. Detectors for high resolution dynamic pet

    International Nuclear Information System (INIS)

    Derenzo, S.E.; Budinger, T.F.; Huesman, R.H.

    1983-05-01

    This report reviews the motivation for high spatial resolution in dynamic positron emission tomography of the head and the technical problems in realizing this objective. We present recent progress in using small silicon photodiodes to measure the energy deposited by 511 keV photons in small BGO crystals with an energy resolution of 9.4% full-width at half-maximum. In conjunction with a suitable phototube coupled to a group of crystals, the photodiode signal to noise ratio is sufficient for the identification of individual crystals both for conventional and time-of-flight positron tomography

  19. Thirteen-Year Evaluation of Highly Cross-Linked Polyethylene Articulating With Either 28-mm or 36-mm Femoral Heads Using Radiostereometric Analysis and Computerized Tomography

    DEFF Research Database (Denmark)

    Nebergall, Audrey K; Greene, Meridith E; Rubash, Harry E

    2016-01-01

    BACKGROUND: The objective of this 13-year prospective evaluation of highly cross-linked ultra high molecular weight polyethylene (HXLPE) was to (1) assess the long-term wear of HXLPE articulating with 2 femoral head sizes using radiostereometric analysis (RSA) and to (2) determine if osteolysis...... is a concern with this material through the use of plain radiographs and computerized tomography (CT). METHODS: All patients received a Longevity HXLPE liner with tantalum beads and either a 28-mm or 36-mm femoral head. Twelve patients (6 in each head size group) agreed to return for 13-year RSA, plain...... scan revealed areas of remodeling of this graft. One patient's 13-year plain radiographs showed evidence of cup loosening and linear radiolucencies in zones 2 and 3. CONCLUSION: There was no evidence of significant wear over time using RSA. The CT scans did not show evidence of osteolysis due to wear...

  20. Value of computerized tomography in the diagnosis of primary and recurrent pituitary gland tumors

    International Nuclear Information System (INIS)

    Imhof, H.; Kuester, W.; Eslami-Nejad, S.

    1979-01-01

    The results of cranial computerized tomography (CCT) of 33 patients with questionable space-occupying lesions in the sella-region are compared with clinical, radiological and surgical reports. Five pituitary gland tumors could be detected for the first time. Four of them are verified by surgery. In eight cases recurrent pituitary glant tumors are suspected. Surprisingly these tumors could be found by surgery only in three cases, while in the remaining five cases only scar-tissue was demonstrable. The high accuracy of CCT in the detection of pituitary gland tumors and the possibility to save the patient expensive and high invasive examinations as well, makes CCT in the presence of corresponding clinical signs to a diagnostic 'must'. It is undecided whether in the cases with possible recurrent tumors, there are real recurrent tumors, which could not be detected by surgery, or only scar tissue. In the latter case scar tissue and recurrent pituitary gland tumors are very similar with CCT. (orig.) 891 MG/orig. 892 CKA [de

  1. Computerized tomography of the traumatic hematoma in the corpus callosum

    International Nuclear Information System (INIS)

    Ogura, Koichiro; Yamamoto, Isao; Hara, Makoto; Suzuki, Yoshio; Nakane, Toshichi; Watanabe, Masao.

    1982-01-01

    The value of the computerized tomography (CT) in the diagnosis of the intracerebral hematoma has been well documented. However, there is little report about the CT findings of the hematoma of the corpus callosum. This report presents two cases of the traumatic hematoma in the corpus callosum and is discussed about their CT findings. Two patients, 52 year-old male and 40 year-old male, respectively, are the cases of blunt mechanical head trauma which were accompanied neither by skull fracture nor by scalp injury. In all these cases, the findings that hematoma occupied from the genu to the body of the corpus callosum were verified by surgery and the axial CT revealed the following two similar findings. First; the hematoma in the genu of the corpus callosum was shown as a cresent-shaped high density mass. This finding seems to be due to the following anatomical structure, that is, the genu of the corpus callosum is located just in front of the anterior horn of the lateral ventricles in the shape of the convex towards posteriorly. Second; as the midportion of the body of the corpus callosum tends to be appeared narrow in width between both lateral ventricles, the hematoma which extended from the genu towards the body of the corpus callosum was shown as a dumbbell-shaped high density mass. (author)

  2. The micro-mechanics of strength, durability and damage tolerance in composites: new insights from high resolution computed tomography

    Science.gov (United States)

    Spearing, S. Mark; Sinclair, Ian

    2016-07-01

    Recent work, led by the authors, on impact damage resistance, particle toughening and tensile fibre failure is reviewed in order to illustrate the use of high-resolution X-ray tomography to observe and quantify damage mechanisms in carbon fibre composite laminates. Using synchrotron and micro-focus X-ray sources resolutions of less than 1 μm have been routinely achieved. This enables individual broken fibres and the micromechanisms of particle toughening to be observed and quantified. The data for fibre failure, cluster formation and overall tensile strength are compared with model predictions. This allows strategies for future model development to be identified. The overall implications for using such high-resolution 3-D measurements to inform a “data-rich mechanics” approach to materials evaluation and modeling is discussed.

  3. In vivo high resolution human corneal imaging using full-field optical coherence tomography.

    Science.gov (United States)

    Mazlin, Viacheslav; Xiao, Peng; Dalimier, Eugénie; Grieve, Kate; Irsch, Kristina; Sahel, José-Alain; Fink, Mathias; Boccara, A Claude

    2018-02-01

    We present the first full-field optical coherence tomography (FFOCT) device capable of in vivo imaging of the human cornea. We obtained images of the epithelial structures, Bowman's layer, sub-basal nerve plexus (SNP), anterior and posterior stromal keratocytes, stromal nerves, Descemet's membrane and endothelial cells with visible nuclei. Images were acquired with a high lateral resolution of 1.7 µm and relatively large field-of-view of 1.26 mm x 1.26 mm - a combination, which, to the best of our knowledge, has not been possible with other in vivo human eye imaging methods. The latter together with a contactless operation, make FFOCT a promising candidate for becoming a new tool in ophthalmic diagnostics.

  4. Resolution, sensitivity, and in vivo application of high-resolution computed tomography for titanium-coated polymethyl methacrylate (PMMA) dental implants

    NARCIS (Netherlands)

    Cuijpers, V.M.J.I.; Jaroszewicz, J.; Anil, S.; Al Farraj Aldosari, A.; Walboomers, X.F.; Jansen, J.A.

    2014-01-01

    OBJECTIVES: The aims of this study were (i) to determine the spatial resolution and sensitivity of micro- versus nano-computed tomography (CT) techniques and (ii) to validate micro- versus nano-CT in a dog dental implant model, comparative to histological analysis. MATERIAL AND METHODS: To determine

  5. Computerized tomography of the lumbar vertebral column after intervertebral disk operation. Pt. 1

    International Nuclear Information System (INIS)

    Schindler, G.; Klott, K.

    1984-01-01

    Problems after intervertebral disk operations are to be expected in about 25-40% of the patients operated. Progressive degnerative alterations at the disks, the vertebrae and the intervertebral joints entail chronic mechanical pain resulting from the sensitive innervation of the structures mentioned, or lead in severe cases to the alteration of the epidural space respectively the spinal nerves with corresponding peripheral neurological symptoms. As post-surgical complications spondylodiscitis, spondylitis, haematomae, liquor fistulae, and split-off bone fragments can be the cause of complaints, for which computerized tomography is a better diagnostical method than myelography. (BWU) [de

  6. Study of the human encephalon morphology by computerized axial tomography in neurological diseases

    International Nuclear Information System (INIS)

    Loynaz Fernandez, Clara Silvia; Milan Companioni, Daile; Gomez Padron, Ivo; Alvarez Leon, Oladys; Espinosa Quiros, Desiderio

    2001-01-01

    Since the middle of the last century, the study of the human encephalon morphology has been of great interest for the researchers. With the introduction of the computerized axial tomography in 1974, it was possible to expand the knowledge about this area and at the same time provide information on the structural lesions that are pathologies of great psychosocial repercussion like epilepsy and Parkinsonism. This paper used 90 tomographic studies on people aged 20-80 years. A series of linear measurements were made and statistically processed. The results showed variations in linear measurements among control, epileptic and Parkinsonian subjects

  7. Reversible bronchial dilatation in children: comparison of serial high-resolution computer tomography scans of the lungs

    Energy Technology Data Exchange (ETDEWEB)

    Gaillard, E.A. E-mail: erol.gaillard@lwh-tr.nwest.nhs.uk; Carty, H.; Heaf, D.; Smyth, R.L

    2003-09-01

    Introduction: bronchiectasis is generally considered irreversible in the adult population, largely based on studies employing bronchography in cases with a significant clinical history. It is assumed, that the same is true for children. Few studies have examined the natural history of bronchiectasis in children and diagnostic criteria on high-resolution computer tomography of the lungs are derived from studies on adults. Frequently, bronchiectasis is reported in children in cases where localised bronchial dilatation is present, incorrectly labelling these children with an irreversible life-long condition. Objective: to evaluate changes in appearance of bronchial dilatation, unrelated to cystic fibrosis in children, as assessed by sequential high-resolution computer tomography (HRCT) of the lungs. Methods: the scans of 22 children with a radiological diagnosis of bronchiectasis, seen at Alder Hey Children's Hospital between 1994 and 2000, who had at least two CT scans of the lungs were reviewed by a single radiologist, who was blinded to the original report. Results: following a median scan interval of 21 months (range 2-43), bronchial dilatation resolved completely in six children and there was improvement in appearances in a further eight, with medical treatment alone. Discussion: a radiological diagnosis of bronchiectasis should be considered with caution in children as diagnostic criteria derived from studies in adults have not been validated in children and the condition is generally considered irreversible.

  8. Basilar expansion of the human sphenoidal sinus: an integrated anatomical and computerized tomography study

    International Nuclear Information System (INIS)

    Haetinger, Rainer G.; Navarro, Joao A.C.; Liberti, Edson A.

    2006-01-01

    Basilar expansion of the sphenoidal sinus (BESS) was studied in order to demonstrate its critical relevance in endoscopic or microscopic endonasal surgical interventions, including access to the sphenoidal sinus itself or in transsphenoidal pituitary approaches. Direct evaluation of anatomical specimens (25 dry skulls and 25 formalin-fixed hemi heads) and the use of computerized tomography (CT) (50 dry skulls and 750 patients) showed a high BESS frequency (69%). The authors considered BESS to be critical when the posterior wall of the clivus was 2-mm thick and found a high incidence of this important anatomical variation (44%). This study also evaluated the relationship between the sinonasal septa, the clivus, and the internal carotid arteries, and a considerable regularity in the location of these structures was seen. The septa were anatomically related to the internal carotid arteries in 55% and to the clivus in 33% of the cases. In conclusion, the high frequency of critical BESS here described is relevant to endoscopic or microscopic endonasal surgical interventions, including access to the sphenoidal sinus itself or in transsphenoidal pituitary approaches. (orig.)

  9. Diagnostic radiology for head and neck neoplasms with emphasis on computerized tomography

    International Nuclear Information System (INIS)

    Weber, A.L.; Manzione, J.V.

    1986-01-01

    The radiologic evaluation of head and neck neoplasms constitutes an important part in their diagnosis and treatment. The introduction of computerized tomography (CT) and the further development of this modality since 1972 have contributed significantly to the staging of these neoplasms. CT not only demonstrates soft tissue densities, but also bony structures, muscles, fascial planes, opacified vascular structures, and enlarged lymph nodes. CT, however, fails to differentiate the various histologic types of lesions in the majority of cases. Features such as size of the lesion, marginal definition, lytic bone destruction, sclerotic bony reaction, bony expansion, calcific densities, fat content, and obliteration of fascial planes are utilized to delimit the spectrum of diagnostic possibilities. Conventional films including tomography are also indicated as preliminary examinations in the investigation of head and neck neoplasms. They provide a survey of the abnormality in question and form the basis for special studies such as CT and angiography. They are often the first examination to demonstrate a lesion that may be suspected from the history and clinical examination. 13 refs.; 11 figs

  10. Computerized tomography of the brain and associated risk factors in 240 patients iwth reversible cerebral ischemic attacks (RIAs)

    International Nuclear Information System (INIS)

    Bozzao, L.; Fantozzi, L.M.; Carolei, A.; Pappata, S.; Vesentini, G.; Allori, L.; Rasura, M.; Fieschi, C.

    1985-01-01

    The frequency and distribution of focal low density cerebral ischemic lesions in RIA patients with regard to factors as age at onset, number and temporal profile of the reversible cerebral ischemic events on admission, presence of associated medical conditions such as hypertension and diabetes mellitus, have been investigated with computerized tomography of the brain. (author). 7 refs.; 1 tab

  11. Transection of the pituitary stalk: evaluation of two cases by computerized tomography and magnetic resonance

    International Nuclear Information System (INIS)

    Amaral, L.L.F. do; Mendonca, R.A.; Natal, M.R.C.

    1992-01-01

    The authors present two cases of pituitary dwarfism where the study by high resolution computed tomography and by magnetic resonance imaging show transection of the pituitary stalk as the cause of the endocrine disturb. The importance of these methods on the investigation of disturbs of the hypothalamus-hypophyseal axis is stressed. (author)

  12. Spectrum of high-resolution computed tomography imaging in occupational lung disease.

    Science.gov (United States)

    Satija, Bhawna; Kumar, Sanyal; Ojha, Umesh Chandra; Gothi, Dipti

    2013-10-01

    Damage to the lungs caused by dusts or fumes or noxious substances inhaled by workers in certain specific occupation is known as occupational lung disease. Recognition of occupational lung disease is especially important not only for the primary worker, but also because of the implications with regard to primary and secondary disease prevention in the exposed co-workers. Although many of the disorders can be detected on chest radiography, high-resolution computed tomography (HRCT) is superior in delineating the lung architecture and depicting pathology. The characteristic radiological features suggest the correct diagnosis in some, whereas a combination of clinical features, occupational history, and radiological findings is essential in establishing the diagnosis in others. In the presence of a history of exposure and consistent clinical features, the diagnosis of even an uncommon occupational lung disease can be suggested by the characteristic described HRCT findings. In this article, we briefly review the HRCT appearance of a wide spectrum of occupational lung diseases.

  13. Spectrum of high-resolution computed tomography imaging in occupational lung disease

    Directory of Open Access Journals (Sweden)

    Bhawna Satija

    2013-01-01

    Full Text Available Damage to the lungs caused by dusts or fumes or noxious substances inhaled by workers in certain specific occupation is known as occupational lung disease. Recognition of occupational lung disease is especially important not only for the primary worker, but also because of the implications with regard to primary and secondary disease prevention in the exposed co-workers. Although many of the disorders can be detected on chest radiography, high-resolution computed tomography (HRCT is superior in delineating the lung architecture and depicting pathology. The characteristic radiological features suggest the correct diagnosis in some, whereas a combination of clinical features, occupational history, and radiological findings is essential in establishing the diagnosis in others. In the presence of a history of exposure and consistent clinical features, the diagnosis of even an uncommon occupational lung disease can be suggested by the characteristic described HRCT findings. In this article, we briefly review the HRCT appearance of a wide spectrum of occupational lung diseases.

  14. Spectrum of high-resolution computed tomography imaging in occupational lung disease

    International Nuclear Information System (INIS)

    Satija, Bhawna; Kumar, Sanyal; Ojha, Umesh Chandra; Gothi, Dipti

    2013-01-01

    Damage to the lungs caused by dusts or fumes or noxious substances inhaled by workers in certain specific occupation is known as occupational lung disease. Recognition of occupational lung disease is especially important not only for the primary worker, but also because of the implications with regard to primary and secondary disease prevention in the exposed co-workers. Although many of the disorders can be detected on chest radiography, high-resolution computed tomography (HRCT) is superior in delineating the lung architecture and depicting pathology. The characteristic radiological features suggest the correct diagnosis in some, whereas a combination of clinical features, occupational history, and radiological findings is essential in establishing the diagnosis in others. In the presence of a history of exposure and consistent clinical features, the diagnosis of even an uncommon occupational lung disease can be suggested by the characteristic described HRCT findings. In this article, we briefly review the HRCT appearance of a wide spectrum of occupational lung diseases

  15. Towards high-resolution positron emission tomography for small volumes

    International Nuclear Information System (INIS)

    McKee, B.T.A.

    1982-01-01

    Some arguments are made regarding the medical usefulness of high spatial resolution in positron imaging, even if limited to small imaged volumes. Then the intrinsic limitations to spatial resolution in positron imaging are discussed. The project to build a small-volume, high resolution animal research prototype (SHARP) positron imaging system is described. The components of the system, particularly the detectors, are presented and brief mention is made of data acquisition and image reconstruction methods. Finally, some preliminary imaging results are presented; a pair of isolated point sources and 18 F in the bones of a rabbit. Although the detector system is not fully completed, these first results indicate that the goals of high sensitivity and high resolution (4 mm) have been realized. (Auth.)

  16. Simultaneous Confocal Scanning Laser Ophthalmoscopy Combined with High-Resolution Spectral-Domain Optical Coherence Tomography: A Review

    Directory of Open Access Journals (Sweden)

    Verônica Castro Lima

    2011-01-01

    Full Text Available We aimed to evaluate technical aspects and the clinical relevance of a simultaneous confocal scanning laser ophthalmoscope and a high-speed, high-resolution, spectral-domain optical coherence tomography (SDOCT device for retinal imaging. The principle of confocal scanning laser imaging provides a high resolution of retinal and choroidal vasculature with low light exposure. Enhanced contrast, details, and image sharpness are generated using confocality. The real-time SDOCT provides a new level of accuracy for assessment of the angiographic and morphological correlation. The combined system allows for simultaneous recordings of topographic and tomographic images with accurate correlation between them. Also it can provide simultaneous multimodal imaging of retinal pathologies, such as fluorescein and indocyanine green angiographies, infrared and blue reflectance (red-free images, fundus autofluorescence images, and OCT scans (Spectralis HRA + OCT; Heidelberg Engineering, Heidelberg, Germany. The combination of various macular diagnostic tools can lead to a better understanding and improved knowledge of macular diseases.

  17. Effect of The Measuring Parameters on The Reconstructed Images by Computerized Tomography

    International Nuclear Information System (INIS)

    Ali, A.M.; Ali, A.M.; Megahid, R.M.

    2011-01-01

    In this paper, the potential of computerized tomography by neutrons and gamma rays as a main precise technique for nondestructive assay of materials and components of prime importance in nuclear and general industries are given and discussed. Both Fast Fourier Transform (FFT) and convolution techniques are introduced. Shepp and Logan human head phantom is used for theoretical testing and studying the effect of translation value for both techniques. Moreover, the effect of the projection number discussed. Comparison between the two reconstruction techniques wasper formed for the examined object. In addition, some of the experimentally scanned images using slit beam of gamma rays emitt ed from the ETRR- 1 reactor are presented and discussed.

  18. Computerized tomography

    International Nuclear Information System (INIS)

    Caille, J.M.; Salamon, G.

    1980-01-01

    As X-ray Ct becomes more commonplace, other techniques of investigation using roughly comparable hardware and software have appeared. Positron-Emission Tomography already provides indispensable physiological and physio-pathological information. Similarly, in the histo-chemical field, Nuclear Magnetic Resonance seems very promising. Some of these new techniques will no doubt shortly be considered as essential as CT in establishing accurate diagnoses non-invasively. (orig./VJ) [de

  19. Three dimensional imaging of damage in structural materials using high resolution micro-tomography

    Energy Technology Data Exchange (ETDEWEB)

    Buffiere, J.-Y. [GEMPPM UMR CNRS 5510, INSA Lyon, 20 Av. A. Einstein, 69621 Villeurbanne Cedex (France)]. E-mail: jean-yves.buffiere@insa-lyon.fr; Proudhon, H. [GEMPPM UMR CNRS 5510, INSA Lyon, 20 Av. A. Einstein, 69621 Villeurbanne Cedex (France); Ferrie, E. [GEMPPM UMR CNRS 5510, INSA Lyon, 20 Av. A. Einstein, 69621 Villeurbanne Cedex (France); Ludwig, W. [GEMPPM UMR CNRS 5510, INSA Lyon, 20 Av. A. Einstein, 69621 Villeurbanne Cedex (France); Maire, E. [GEMPPM UMR CNRS 5510, INSA Lyon, 20 Av. A. Einstein, 69621 Villeurbanne Cedex (France); Cloetens, P. [ESRF Grenoble (France)

    2005-08-15

    This paper presents recent results showing the ability of high resolution synchrotron X-ray micro-tomography to image damage initiation and development during mechanical loading of structural metallic materials. First, the initiation, growth and coalescence of porosities in the bulk of two metal matrix composites have been imaged at different stages of a tensile test. Quantitative data on damage development has been obtained and related to the nature of the composite matrix. Second, three dimensional images of fatigue crack have been obtained in situ for two different Al alloys submitted to fretting and/or uniaxial in situ fatigue. The analysis of those images shows the strong interaction of the cracks with the local microstructure and provides unique experimental data for modelling the behaviour of such short cracks.

  20. Three dimensional imaging of damage in structural materials using high resolution micro-tomography

    International Nuclear Information System (INIS)

    Buffiere, J.-Y.; Proudhon, H.; Ferrie, E.; Ludwig, W.; Maire, E.; Cloetens, P.

    2005-01-01

    This paper presents recent results showing the ability of high resolution synchrotron X-ray micro-tomography to image damage initiation and development during mechanical loading of structural metallic materials. First, the initiation, growth and coalescence of porosities in the bulk of two metal matrix composites have been imaged at different stages of a tensile test. Quantitative data on damage development has been obtained and related to the nature of the composite matrix. Second, three dimensional images of fatigue crack have been obtained in situ for two different Al alloys submitted to fretting and/or uniaxial in situ fatigue. The analysis of those images shows the strong interaction of the cracks with the local microstructure and provides unique experimental data for modelling the behaviour of such short cracks

  1. Toward robust high resolution fluorescence tomography: a hybrid row-action edge preserving regularization

    Science.gov (United States)

    Behrooz, Ali; Zhou, Hao-Min; Eftekhar, Ali A.; Adibi, Ali

    2011-02-01

    Depth-resolved localization and quantification of fluorescence distribution in tissue, called Fluorescence Molecular Tomography (FMT), is highly ill-conditioned as depth information should be extracted from limited number of surface measurements. Inverse solvers resort to regularization algorithms that penalize Euclidean norm of the solution to overcome ill-posedness. While these regularization algorithms offer good accuracy, their smoothing effects result in continuous distributions which lack high-frequency edge-type features of the actual fluorescence distribution and hence limit the resolution offered by FMT. We propose an algorithm that penalizes the total variation (TV) norm of the solution to preserve sharp transitions and high-frequency components in the reconstructed fluorescence map while overcoming ill-posedness. The hybrid algorithm is composed of two levels: 1) An Algebraic Reconstruction Technique (ART), performed on FMT data for fast recovery of a smooth solution that serves as an initial guess for the iterative TV regularization, 2) A time marching TV regularization algorithm, inspired by the Rudin-Osher-Fatemi TV image restoration, performed on the initial guess to further enhance the resolution and accuracy of the reconstruction. The performance of the proposed method in resolving fluorescent tubes inserted in a liquid tissue phantom imaged by a non-contact CW trans-illumination FMT system is studied and compared to conventional regularization schemes. It is observed that the proposed method performs better in resolving fluorescence inclusions at higher depths.

  2. High-definition velocity-space tomography of fast-ion dynamics

    DEFF Research Database (Denmark)

    Salewski, Mirko; Geiger, B.; Jacobsen, A.S.

    2016-01-01

    Velocity-space tomography of the fast-ion distribution function in a fusion plasma is usually a photon-starved tomography method due to limited optical access and signal-to-noise ratio of fast-ion Dα (FIDA) spectroscopy as well as the strive for high-resolution images. In high-definition tomography...... information to reconstruct where in velocity space the measurements and the simulation disagree. This alternative approach is demonstrated for four-view as well as for two-view FIDA measurements. The high-definition tomography tools allow us to study fast ions in sawtoothing plasmas and the formation of NBI...

  3. Ultra high resolution soft x-ray tomography

    International Nuclear Information System (INIS)

    Haddad, W.S.; Trebes, J.E.; Goodman, D.M.

    1995-01-01

    Ultra high resolution three dimensional images of a microscopic test object were made with soft x-rays using a scanning transmission x-ray microscope. The test object consisted of two different patterns of gold bars on silicon nitride windows that were separated by ∼5μm. A series of nine 2-D images of the object were recorded at angles between -50 to +55 degrees with respect to the beam axis. The projections were then combined tomographically to form a 3-D image by means of an algebraic reconstruction technique (ART) algorithm. A transverse resolution of ∼1000 Angstrom was observed. Artifacts in the reconstruction limited the overall depth resolution to ∼6000 Angstrom, however some features were clearly reconstructed with a depth resolution of ∼1000 Angstrom. A specially modified ART algorithm and a constrained conjugate gradient (CCG) code were also developed as improvements over the standard ART algorithm. Both of these methods made significant improvements in the overall depth resolution bringing it down to ∼1200 Angstrom overall. Preliminary projection data sets were also recorded with both dry and re-hydrated human sperm cells over a similar angular range

  4. Ultra high resolution soft x-ray tomography

    International Nuclear Information System (INIS)

    Haddad, W.S.; Trebes, J.E.; Goodman, D.M.; Lee, H.R.; McNulty, I.; Zalensky, A.O.

    1995-01-01

    Ultra high resolution three dimensional images of a microscopic test object were made with soft x-rays using a scanning transmission x-ray microscope. The test object consisted of two different patterns of gold bars on silicon nitride windows that were separated by ∼5 microm. A series of nine 2-D images of the object were recorded at angles between -50 to +55 degrees with respect to the beam axis. The projections were then combined tomographically to form a 3-D image by means of an algebraic reconstruction technique (ART) algorithm. A transverse resolution of ∼ 1,000 angstrom was observed. Artifacts in the reconstruction limited the overall depth resolution to ∼ 6,000 angstrom, however some features were clearly reconstructed with a depth resolution of ∼ 1,000 angstrom. A specially modified ART algorithm and a constrained conjugate gradient (CCG) code were also developed as improvements over the standard ART algorithm. Both of these methods made significant improvements in the overall depth resolution, bringing it down to ∼ 1,200 angstrom overall. Preliminary projection data sets were also recorded with both dry and re-hydrated human sperm cells over a similar angular range

  5. Phase contrast enhanced high resolution X-ray imaging and tomography of soft tissue

    International Nuclear Information System (INIS)

    Jakubek, Jan; Granja, Carlos; Dammer, Jiri; Hanus, Robert; Holy, Tomas; Pospisil, Stanislav; Tykva, Richard; Uher, Josef; Vykydal, Zdenek

    2007-01-01

    A tabletop system for digital high resolution and high sensitivity X-ray micro-radiography has been developed for small-animal and soft-tissue imaging. The system is based on a micro-focus X-ray tube and the semiconductor hybrid position sensitive Medipix2 pixel detector. Transmission radiography imaging, conventionally based only on absorption, is enhanced by exploiting phase-shift effects induced in the X-ray beam traversing the sample. Phase contrast imaging is realized by object edge enhancement. DAQ is done by a novel fully integrated USB-based readout with online image generation. Improved signal reconstruction techniques make use of advanced statistical data analysis, enhanced beam hardening correction and direct thickness calibration of individual pixels. 2D and 3D micro-tomography images of several biological samples demonstrate the applicability of the system for biological and medical purposes including in-vivo and time dependent physiological studies in the life sciences

  6. High-resolution 3D imaging of polymerized photonic crystals by lab-based x-ray nanotomography with 50-nm resolution

    Science.gov (United States)

    Yin, Leilei; Chen, Ying-Chieh; Gelb, Jeff; Stevenson, Darren M.; Braun, Paul A.

    2010-09-01

    High resolution x-ray computed tomography is a powerful non-destructive 3-D imaging method. It can offer superior resolution on objects that are opaque or low contrast for optical microscopy. Synchrotron based x-ray computed tomography systems have been available for scientific research, but remain difficult to access for broader users. This work introduces a lab-based high-resolution x-ray nanotomography system with 50nm resolution in absorption and Zernike phase contrast modes. Using this system, we have demonstrated high quality 3-D images of polymerized photonic crystals which have been analyzed for band gap structures. The isotropic volumetric data shows excellent consistency with other characterization results.

  7. Testing objects in Computerized Axial Tomography. Contributions to the Spanish Protocol on quality control in radiodiagnostics

    International Nuclear Information System (INIS)

    Villaescusa, J.I.; Campayo, J.M.

    1995-01-01

    In the provisional version of the Spanish Protocol about the technical aspects of Quality Control in Radiodiagnostic,SEFM-SEPR 1993, it is dedicated a section to Computerized Axial tomography, establishing a total of eleven technical parameters of the equipment for examination. The present work describes the practical use of the Protocol using various types of Test Object. The authors also propose new tests that should be considered in the final version of the Spanish Protocol. (Author)

  8. Initial characterization of a BGO-photodiode detector for high resolution positron emission tomography

    International Nuclear Information System (INIS)

    Derenzo, S.E.

    1983-11-01

    Spatial resolution in positron emission tomography is currently limited by the resolution of the detectors. This work presents the initial characterization of a detector design using small bismuth germanate (BGO) crystals individually coupled to silicon photodiodes (SPDs) for crystal identification, and coupled in groups to phototubes (PMTs) for coincidence timing. A 3 mm x 3 mm x 3 mm BGO crystal coupled only to an SPD can achieve a 511 keV photopeak resolution of 8.7% FWHM at -150 0 C, using a pulse peaking time of 10 μs. When two 3 mm x 3 mm x 15 mm BGO crystals are coupled individually to SPDs and also coupled to a common 14 mm diam PMT, the SPDs detect the 511 keV photopeak with a resolution of 30% FWHM at -76 0 C. In coincidence with an opposing 3 mm wide BGO crystal, the SPDs are able to identify the crystal of interaction with good signal-to-noise ratio, and the detector pair resolution is 2 mm FWHM. 32 references, 7 figures, 3 tables

  9. Submicron Resolution Spectral-Domain Optical Coherence Tomography

    KAUST Repository

    Alarousu, Erkki

    2013-11-14

    Apparatuses and systems for submicron resolution spectral-domain optical coherence tomography (OCT) are disclosed. The system may use white light sources having wavelengths within 400-1000 nanometers, and achieve resolution below 1 .mu.m. The apparatus is aggregated into a unitary piece, and a user can connect the apparatus to a user provided controller and/or light source. The light source may be a supercontinuum source.

  10. High-resolution computed tomography findings in eight patients with hantavirus pulmonary syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Barbosa, Diego de Lacerda; Hochhegger, Bruno; Souza Junior, Arthur Soares; Zanetti, Glaucia; Escuissato, Dante Luiz; Meirelles, Gustavo de Souza Portes; Funari, Marcelo Buarque de Gusmao; Marchiori, Edson, E-mail: edmarchiori@gmail.com [Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ (Brazil); Santa Casa de Porto Alegre, Porto Alegre, RS (Brazil); Faculdade de Medicina de Sao Jose do Rio Preto (FAMERP), SP (Brazil); Ultra X, Sao Jose do Rio Preto, SP (Brazil); Universidade Federal do Parana (UFPR), Curitiba, PR (Brazil); Universidade Federal de Sao Paulo (UNIFESP), Sao Paulo, SP (Brazil); Grupo Fleury, Sao Paulo, SP (Brazil); Universidade de Sao Paulo (FM/USP), Sao Paulo, SP (Brazil). Faculdade de Medicina

    2017-05-15

    Objective: The purpose of this study was to describe the high-resolution computed tomography (HRCT) findings in patients with hantavirus pulmonary syndrome (HPS). Materials and Methods: We retrospectively reviewed HRCT findings from eight cases of HPS. All patients were men, aged 19-70 (mean, 41.7) years. Diagnoses were established by serological test (enzyme-linked immunosorbent assay) in all patients. Two chest radiologists analyzed the images and reached decisions by consensus. Results: The predominant HRCT findings were ground-glass opacities (GGOs) and smooth inter- and intralobular septal thickening, found in all eight cases; however, the crazy-paving pattern was found in only three cases. Pleural effusion and peribronchovascular thickening were observed in five patients. The abnormalities were bilateral in all patients. Conclusion: The predominant HRCT findings in patients with HPS were GGOs and smooth inter- and intralobular septal thickening, which probably correlate with the histopathologic findings of pulmonary edema. (author)

  11. High-resolution computed tomography findings in eight patients with hantavirus pulmonary syndrome

    International Nuclear Information System (INIS)

    Barbosa, Diego de Lacerda; Hochhegger, Bruno; Souza Junior, Arthur Soares; Zanetti, Glaucia; Escuissato, Dante Luiz; Meirelles, Gustavo de Souza Portes; Funari, Marcelo Buarque de Gusmao; Marchiori, Edson; Santa Casa de Porto Alegre, Porto Alegre, RS; Faculdade de Medicina de Sao Jose do Rio Preto; Ultra X, Sao Jose do Rio Preto, SP; Universidade Federal do Parana; Universidade Federal de Sao Paulo; Grupo Fleury, Sao Paulo, SP; Universidade de Sao Paulo

    2017-01-01

    Objective: The purpose of this study was to describe the high-resolution computed tomography (HRCT) findings in patients with hantavirus pulmonary syndrome (HPS). Materials and Methods: We retrospectively reviewed HRCT findings from eight cases of HPS. All patients were men, aged 19-70 (mean, 41.7) years. Diagnoses were established by serological test (enzyme-linked immunosorbent assay) in all patients. Two chest radiologists analyzed the images and reached decisions by consensus. Results: The predominant HRCT findings were ground-glass opacities (GGOs) and smooth inter- and intralobular septal thickening, found in all eight cases; however, the crazy-paving pattern was found in only three cases. Pleural effusion and peribronchovascular thickening were observed in five patients. The abnormalities were bilateral in all patients. Conclusion: The predominant HRCT findings in patients with HPS were GGOs and smooth inter- and intralobular septal thickening, which probably correlate with the histopathologic findings of pulmonary edema. (author)

  12. Positron emission tomography with Positome, 2

    International Nuclear Information System (INIS)

    Nukui, Hideaki; Yamamoto, Y.L.; Thompson, C.J.; Feindel, W.

    1979-01-01

    Positron emission tomography with Positome II using 68 Ga-EDTA was performed in cases with brain tumor and cerebral arteriovenous malformation. A significant focal uptake in static study and hemodynamic changes in dynamic study were noted in all cases except one case with intracranial lipoma. Comparing this method with sup(99m) Tc-pertechnetate cerebral image study and computerized axial tomography, the diagnostic rate for detecting brain tumor was almost equal in all of these three methods. However, detecting and localizing was easier and clearer in static positron emission tomography with 68 Ga-EDTA than in sup(99m) Tc-pertechnetate cerebral image and computerized axial tomography without infusion of contrast medium. Furthermore, static positron emission tomography with 68 Ga-EDTA was superior to computerized axial tomography without infusion of contrast medium for detecting cerebral arteriovenous malformation. Concerning dynamic positron emission tomography with 68 Ga-EDTA, semiquantitative values obtained by this method correlated well with findings of computerized axial tomography and was thought to be more precise and in detail than the findings of sup(99m) Tc-pertechnetate cerebral image study. Summation of the previous studies about dynamic positron emission tomography with 77 Kr in occlusive cerebrovascular disease is also reported. In conclusion, static positron emission tomography with 68 Ga-EDTA is a very useful diagnostic method for detecting and localizing brain tumor and cerebral arteriovenous malformation without any attendant complications. Furthermore, a good combination of static and dynamic positron emission tomography and computerized axial tomography appear to be outstandingly effective for not only detecting the lesion but also understanding the pathophysiological aspect in cases with various intracranial lesions. (author)

  13. The Spectrum of Presentations of Cryptogenic Organizing Pneumonia in High Resolution Computed Tomography

    International Nuclear Information System (INIS)

    Mehrian, Payam; Shahnazi, Makhtoom; Dahaj, Ali Ahmadi; Bizhanzadeh, Sorour; Karimi, Mohammad Ali

    2014-01-01

    Various radiologic patterns of cryptogenic organizing pneumonia (COP) in X-rays have been reported for more than 20 years, and later, in computed tomography scans. The aim of the present study was to describe the spectrum of radiologic findings on high resolution computed tomography (HRCT) scans in patients with COP. HRCT scans of 31 sequential patients (mean age: 54.3±11 years; 55% male) with biopsy-proven COP in a tertiary lung center between 2009 and 2012 were reviewed by two experienced pulmonary radiologists with almost perfect interobserver agreement (kappa=0.83). Chest HRCTs from the lung apex to the base were performed using a 16-slice multi-detector CT scanner. The most common HRCT presentation of COP was ground-glass opacity (GGO) in 83.9% of cases, followed by consolidation in 71%. Both findings were mostly asymmetric bilateral and multifocal. Other common findings were the reverse halo (48.4%), parenchymal bands (54.8%) and subpleural bands (32.3%). Pulmonary nodules were found in about one-third of patients and were frequently smaller than 5 mm in diameter. Both GGOs and consolidations were revealed more often in the lower lobes. The main presentations of COP on HRCT include bilateral GGOs and consolidations in the lower lobes together with the reverse halo sign

  14. Computerized tomography in evaluation of decreased acetabular and femoral anteversion

    International Nuclear Information System (INIS)

    Toennis, D.; Skamel, H.J.

    2003-01-01

    Computerized tomography has received a new importance. It has been shown that decreased anteversion of femur and acetabulum, when both have decreased angles, are causing pain and osteoarthritis of the hip joint. Operative treatment should be performed before osteoarthritis develops. Exact measurements therefore are necessary. The investigation should be performed in prone position to have the pelvis lying in a defined and normal position. Femoral torsion is measured between the transverse axis of the knee and the femoral neck. The transverse axis for measurement of the femoral anteversion is defined by a rectangular line to the sagittal plane. For evaluation of the femoral anteversion in total the angle of the condyles has to be added to the femoral neck angle when the knee is found in internal rotation. Acetabular anteversion should be measured at the level where the femoral head is still in full contact and congruence with the anterior margin of the acetabulum. (orig.) [de

  15. Computerized tomography using water to render the gastrointestinal tract opaque

    International Nuclear Information System (INIS)

    Gaa, J.; Deininger, H.K.; Georgi, M.

    1993-01-01

    An account is given of the technical procedure and results of computerized tomography in the examination of various gastrointestinal disorders using water as an oral and rectal contrast medium. The experience gained so far points to the fact that water as a contrast medium is mainly suitable in the preoperative staging of malignant gastric and colorectal tumours. The rectal injection of water further appears to be favourable in investigations for recidivation following deep anterior resection without impairment of the excretory functions. Our own results were contrary to the findings of other authors in that we had no difficulty in visualizing distal sections of the small intestine in patients suffering from Crohn's disease. The use of water as a contrast medium can, however, not be recommended in the presence of intra-abdominal abscesses, ascites or cystic tumours, as such changes cannot clearly be differentiated from intestinal loops filled with water. (orig./MG) [de

  16. On the pathogenesis of traumatic intracerebral hematoma with a sequential study of computerized tomography

    International Nuclear Information System (INIS)

    Ohmori, Hidetoshi; Miyazaki, Shinichiro; Munekata, Katsuharu; Fukushima, Hiromi; Shohji, Akira.

    1981-01-01

    A sequential study with computerized tomography (CT scan) of two cases of traumatic intracerebral hematoma is reported. Case 1 was a 69-year-old man who had a head injury. The initial CT scan, taken 1 hour after his injury, showed a left temporal salt-and-pepper appearance, which proved to be a cerebral contusion. The CT scan 4.5 hours after his injury showed a left temporal high density area instead. An operation was performed, and a massive intracerebral hematoma was observed. Case 2 was a 61-year-old man who was also admitted because of a head injury. The initial CT scan, taken 1 hour after his injury, revealed several bifrontal intracerebral hemorrhagic spots in the low-density areas, suggesting contusion. A secondary CT scan (23 hours) demonstrated that the traumatic intracerebral hematoma had developed into a posttraumatic cerebral contusion. The operation disclosed a hematoma surrounded by contusion. These cases prove that traumatic intracerebral hematoma is often caused by cerebral contusion. (author)

  17. Halo sign nodules in angio invasive pulmonary aspergillosis: correlation of high-resolution computed tomography findings with anatomopathology; Nodulos com sinal do halo na aspergilose pulmonar angioinvasiva: correlacao da tomografia computadorizada de alta resolucao com a anatomopatologia

    Energy Technology Data Exchange (ETDEWEB)

    Marchiori, Edson [Universidade Federal Fluminense, Niteroi, RJ (Brazil). Dept. de Radiologia; Valiante, Paulo Marcos [Universidade Federal, Rio de Janeiro, RJ (Brazil). Dept. de Patologia; Souza Junior, Arthur Soares [Faculdade de Medicina de Sao Jose do Rio Preto (FAMERP), SP (Brazil). Disciplina de Radiologia

    2002-08-01

    The aim of this study was to correlate the early findings observed on high-resolution computed tomography with anatomopathology results of patients with angio invasive aspergillosis. The authors studied two patients with leukemia. The nodules seen on high-resolution computed tomography corresponded to areas of hemorrhagic infarction, necrotic coagulation and fungal hyphae infiltration whereas ground glass halo corresponded to intra alveolar hemorrhage. Nodules with halo sign were closely correlated with anatomopathology findings. We concluded that the anatomopathology findings can clearly explain the image features of the lesions observed on high-resolution computed tomography. (author)

  18. Analysis of the percentage voids of test and field specimens using computerized tomography

    International Nuclear Information System (INIS)

    Braz, D.; Lopes, R.T.; Motta, L.M.G. da

    1999-01-01

    Computerized tomography has been an excellent tool of analysis of asphaltics mixtures, because it allows comparison of the quality and integrity of test and field specimens. It was required to detect and follow the evolution of cracks, when these mixtures were submitted to fatigue tests, and also helping to interpret the distribution of tensions and deformations which occur in the several types of solicitations imposed to the mixtures. Comparing the medium values of percentage voids obtained from tomographic images with the project's values, it can be observed that the values of test and field specimens for the wearing course are closer to the ones of the project than the ones of the binder. It can be verified that the wearing course specimens always present a distribution of the aggregate, and voids quite homogeneously in the whole profile of the sample, while the binder specimens show an accentuated differentiation of the same factors in the several heights of the sample. Therefore, when choosing a slice for tomography, these considerations should be taken into account

  19. Problems of cranial computer-tomography

    Energy Technology Data Exchange (ETDEWEB)

    Seitz, D [Allgemeines Krankenhaus St. Georg, Hamburg (Germany, F.R.). Neurologische Abt.

    1979-07-01

    The author discusses the problems that have cropped up since the introduction of computerized tomography 5 years ago. To begin with, problems of contrast and object resolution are discussed with a special view to the importance of amipague imaging of cisterns, in particular in the detection of basal growing and displacing, intracranial processes. After this, the tasks of computerized tomography in neurological and neurosurgical emergencies, cerebrocranial injuries, cerebral circulation disturbances, inflammatory diseases of the central nervous systems, epileptic seizures, and chronical headaches are reviewed. Special regard is given to the problem of recurrent examinations and course control, especially in cerebral tumours and aresorptive hydrocephalus. Another paragraph deals with the correlation between CT findings, clinical symptoms, and clinical findings. The importance of cranial CT for neurological diagnoses is illustrated by the change of indications for conventional methods of examination. The limits of the method are shown and it is pointed out that cranial CT is not a search technique but that it requires previous examinations by a neurologist, neurosurgeon, or neuropaediatrician.

  20. Problems of cranial computer-tomography

    International Nuclear Information System (INIS)

    Seitz, D.

    1979-01-01

    The author discusses the problems that have cropped up since the introduction of computerized tomography 5 years ago. To begin with, problems of contrast and object resolution are discussed with a special view to the importance of amipague imaging of cisterns, in particular in the detection of basal growing and displacing, intracranial processes. After this, the tasks of computerized tomography in neurological and neurosurgical emergencies, cerebrocranial injuries, cerebral circulation disturbances, inflammatory diseases of the central nervous systems, epileptic seizures, and chronical headaches are reviewed. Special regard is given to the problem of recurrent examinations and course control, especially in cerebral tumours and aresorptive hydrocephalus. Another paragraph deals with the correlation between CT findings, clinical symptoms, and clinical findings. The importance of cranial CT for neurological diagnoses is illustrated by the change of indications for conventional methods of examination. The limits of the method are shown and it is pointed out that cranial CT is not a search technique but that it requires previous examinations by a neurologist, neurosurgeon, or neuropaediatrician. (orig.) [de

  1. Comparison between high-resolution computed tomography and 99mTc-technegas SPECT pulmonary emphysema

    International Nuclear Information System (INIS)

    Nakano, Satoru; Satoh, Katashi; Takahashi, Kazue

    1996-01-01

    Scintigraphy with 99m Tc-technegas was recently introduced for clinical imaging of lung ventilation. This method has been found to be useful in emergencies, to be more suitable for single photon emission computed tomography (SPECT) than other agents used in ventilation scintigraphy, and could reveal abnormalities in ventilation more easily than high resolution computed tomography (HRCT) in pulmonary emphysema. We compared 99m Tc-technegas SPECT with HRCT in six regions: the right upper, middle, and lower lobes, the left upper lobe, the lingula, and the left lower lobe, in 15 patients with pulmonary emphysema. Patients with centrilobular emphysema tended to show stronger changes in upper lobes than in lower lobes on both 99m Tc-technegas SPECT and HRCT. Some regions showed no change on HRCT but various changes on 99m Tc-SPECT. Patients with panlobular emphysema showed severe changes on 99m Tc-SPECT in lower lung fields in which well-demarcated areas of low attenuation were not seen on HRCT. We conclude that 99m Tc-SPECT is useful for detecting early changes and panlobular changes in pulmonary emphysema. (author)

  2. Transformations and algorithms in a computerized brain atlas

    International Nuclear Information System (INIS)

    Thurfjell, L.; Bohm, C.; Eriksson, L.; Karolinska Institute/Hospital, Stockholm

    1993-01-01

    The computerized brain atlas constructed at the Karolinska Hospital, Stockholm, Sweden, has been further developed. This atlas was designed to be employed in different fields of neuro imaging such as positron emission tomography (PET), single photon emission tomography (SPECT), computerized tomography (CT) and magnetic resonance imaging (MR). The main objectives with the atlas is to aid the interpretation of functional images by introducing anatomical information, to serve as a tool in the merging of data from different imaging modalities and to facilitate the comparisons of data from different individuals by allowing for anatomical standardization of individual data. The purpose of this paper is to describe the algorithms and transformations used in the implementation of the atlas software

  3. Second Mesiobuccal Root Canal of Maxillary First Molars in a Brazilian Population in High-Resolution Cone-Beam Computed Tomography.

    Science.gov (United States)

    Gomes Alves, Claudia Rezende; Martins Marques, Márcia; Stella Moreira, Maria; Harumi Miyagi de Cara, Sueli Patricia; Silveira Bueno, Carlos Eduardo; Lascala, Cesar Ângelo

    2018-01-01

    The second canal of the mesiobuccal root (MB2) of the maxillary first molars (MFM) is difficult to detect in conventional radiographs and can be a major cause of failure in endodontic treatments. The aim of this study was to investigate the prevalence and anatomy of the MB2 by using high-resolution cone-beam computed tomography (CBCT). Three radiologists examined 414 high-resolution CBCTs. Of these, the CBCTs of 287 patients (mean age 49.43±16.76) who had at least one MFM were selected, making a total of 362 teeth. Prevalence and its relation with gender and age of the patients, side of the tooth, and Vertucci's classification were analyzed. Data were statistically analyzed ( P molars in this Brazilian population examined with high-resolution CBTCs is 68.23%, being more prevalent in young patients. Gender and the side examined are no factors for determining the presence of MB2. Although the both FOVs of the high-resolution CBTCs (FOV 8 and 5) detect the MB2 canal, smaller FOV (FOV 5) is more accurate in the analysis of the internal anatomy of such root canals, according to the Vertucci´s classification.

  4. High energy near- and far-field ptychographic tomography at the ESRF

    Science.gov (United States)

    da Silva, Julio C.; Haubrich, Jan; Requena, Guillermo; Hubert, Maxime; Pacureanu, Alexandra; Bloch, Leonid; Yang, Yang; Cloetens, Peter

    2017-09-01

    In high-resolution tomography, one needs high-resolved projections in order to reconstruct a high-quality 3D map of a sample. X-ray ptychography is a robust technique which can provide such high-resolution 2D projections taking advantage of coherent X-rays. This technique was used in the far-field regime for a fair amount of time, but it can now also be implemented in the near-field regime. In both regimes, the technique enables not only high-resolution imaging, but also high sensitivity to the electron density of the sample. The combination with tomography makes 3D imaging possible via ptychographic X-ray computed tomography (PXCT), which can provide a 3D map of the complex-valued refractive index of the sample. The extension of PXCT to X-ray energies above 15 keV is challenging, but it can allow the imaging of object opaque to lower energy. We present here the implementation and developments of high-energy near- and far-field PXCT at the ESRF.

  5. Imaging of basal cell carcinoma by high-definition optical coherence tomography

    DEFF Research Database (Denmark)

    Boone, M A L M; Norrenberg, S; Jemec, G B E

    2012-01-01

    With the continued development of noninvasive therapies for basal cell carcinoma (BCC) such as photodynamic therapy and immune therapies, noninvasive diagnosis and monitoring become increasingly relevant. High-definition optical coherence tomography (HD-OCT) is a high-resolution imaging tool, wit......, with micrometre resolution in both transversal and axial directions, enabling visualization of individual cells up to a depth of around 570 μm, and filling the imaging gap between conventional optical coherence tomography (OCT) and reflectance confocal microscopy (RCM)....

  6. Value of the computerized axial tomography for early diagnosis of cranio cerebral trauma

    International Nuclear Information System (INIS)

    Rodriguez Cheong, Maricel; Dosouto Infante, Vivian; Rosales Fargie, Yamile

    2010-01-01

    A descriptive and cross-sectional study was conducted in 62 patients with cranio cerebral trauma admitted to 'Saturnino Lora' Provincial Teaching Hospital of Santiago de Cuba, from January 2005 to May 2006, in whom computerized axial tomography indicated at the emergency room was performed with the purpose of evaluating the effectiveness of this radiographic technique for early diagnosis of the injury. In the case material there was neither association between the source and imaging results, nor between the age and sex. The main clinical manifestations were vomiting, headache and motor deficit as well as frontal location, intraparenchymatous hematoma (the latter as the most common image finding) and the hyperdense area as tomographic pattern. The survival was of 91,9%

  7. Study of Pelvicaliceal Anatomy by Helical Computerized Tomography

    International Nuclear Information System (INIS)

    Al-Qahtani, Fahd N.; Ali, Gaber A.; Kamal, Baher A.; Taha, Saud A.

    2003-01-01

    To evaluate the role of 3-dimensional images produced by computerized tomography (CT), using intravenous contrast, to study pelvicaliceal anatomy.This might be of help in endourological procedure. The study was conducted in the King Fahd Hospital of the University, King Faisal University. Dammam,Kingdom of Saudi Arabia. The study took place from July 2002 through to October 2002 .Helical CT was carried for patients who were investigated using excretory urography for any reason. A CT was carried out to the kidneys only within 10 minutes ( between 5 and 15 minute films of excretory urography).Images were reprocessed by 3-dimension construction after subtracting all structures except for the palvicaliceal system. Thity-six normal kidneys were studied. The upper pole was drained by a single caliceal infundibulum in all 36(100%) kidneys.the middle segement of the kidney was drained by 2 infundibula in 32 (89%) kidneys. Four (11%) kidneys have no middle caliceal infudibula. The lower pole was drained by 2 caliceal infundibula in 23 (64%) and a single infundibulum in 13 (36%) kidneys. The minor calices draining each renal segment were seen clearly. Three-dimensional images derived by helical CT are feasible for evaluating the anatomy of palvicaliceal system,and, can be of help in endourological procedures. (author)/

  8. Computerized tomography and prognosis in paediatric head injury

    International Nuclear Information System (INIS)

    Tomberg, T.; Rink, U.; Pikkoja, E.; Tikk, A.

    1996-01-01

    The authors have analysed the computerized tomography (CT) findings and their correlation with the clinical state, early and late outcome in children and adolescents with head injuries (HI). This study represents clinical and CT data of 82 consecutive HI patients under 18 years of age. Among them 51 (62%) were boys and 31 (38 %) girls. The application of CT to the evaluation of the morphologic manifestations of HI in children has shown some differences in forms and mechanisms of injury and in outcome compared to adults. In the paediatric HI the most frequent finding was diffuse brain swelling with CT evidence of ventricular and cisternal compression or obliteration. Prognostically the most unfavourable findings were shearing injury, intracerebral and subdural haematomas combined with brain swelling and parenchymal damage. According to the Lidcombe impairment scale, outcome from severe paediatric HI was determined in the 3rd and 6th months, one year and 2 years after the injury. The outcome two years after severe HI varied to a great extent and was better in children than in adults. Although there was long-term disruption of the patient's quality of life, our data show that as there are no predictors of individual outcomes in child HI, no child should be excluded from early and long-term rehabilitation. (author)

  9. The high-grade interpolator: a means for enhancing the resolution of helical computed tomography images of the lung

    International Nuclear Information System (INIS)

    Garcia-Santos, J. M.; Torres del rio, S.; Blanco, A.; Rodriguez, R.; Parlorio, E.; Garcia, A.; Girela, E.; Hernandez, M. D.; Canteras, M.

    2002-01-01

    The purpose of this study was to demonstrate that the use of a high-grade interpolator in the reconstruction of images of the chest increases the resolution, independently of the high-resolution filter. Eight independent observers in two groups (experts and non experts) assessed (two readings separated by a time interval) the same section of the chest reconstructed four times (st-st, st-xs, b-st, b-xs), combining standard (st) and high-resolution (b) filters and standard (st) and high-grade (xs) interpolators. The images were classified from greater to lesser in terms of the resolution perceived. The results were used to compare the degree of resolution introduced by the interpolator and the filter and to determine whether or not there existed variability between observers and between the observations of each, and whether experience played a role in the findings. Six of the eight observers assigned the b-xs images the highest degree of resolution in the majority of cases, followed by the b-st image, the st-xs image and, finally, the st-st image). The other tow observers (one expert and one nonexpert) different only with respect to the order of the st-xs and b-st images, which they assigned the second and third places, respectively. The expert group showed no intra observer variability, while two of the nonexpert observers did. The high-grade interpolator enhances the resolution of images of the chest regardless of who evaluates them, while it does not substantially increase image noise. Thus, its use is recommended in helical computed tomography imaging of the lung. (Author) 10 refs

  10. Dose evaluation in diagnostic for computerized tomography; Evaluacion de dosis en diagnostico por tomografia computarizada

    Energy Technology Data Exchange (ETDEWEB)

    Flores, W.; Borges, J.C.; Mota, H. [Universidad Federal de Rio de Janeiro, PEN/COPPE/UFRJ. Caixa Postal 68509. 21945-970 Rio de Janeiro (Brazil)

    1998-12-31

    The patients which are subjected to computerized tomography tests are exposed to relatively high doses given as result doses on organs that are not matter to test. It was realized a dose levels raising in patients subjected to tests by T C, utilizing to measure this magnitude, TLD-100 thermoluminescent dosemeters which were put directly on the patient, in eye regions, thyroid, breast and navel; founding doses fluctuating between 29.10-49.39 mGy in organs examined and dose values between 0.21-29.10 mGy for organs that no matter to test. The applications of ionizing radiations in medicine do not have dose limits, but paying attention to the radiological protection optimization principle, it is recommended the use of clothes to anti-rays protection for zones not examined, getting with this to reduce the level doses as low as possible, without this to diminish the test quality. (Author)

  11. Interior tomography in microscopic CT with image reconstruction constrained by full field of view scan at low spatial resolution

    Science.gov (United States)

    Luo, Shouhua; Shen, Tao; Sun, Yi; Li, Jing; Li, Guang; Tang, Xiangyang

    2018-04-01

    In high resolution (microscopic) CT applications, the scan field of view should cover the entire specimen or sample to allow complete data acquisition and image reconstruction. However, truncation may occur in projection data and results in artifacts in reconstructed images. In this study, we propose a low resolution image constrained reconstruction algorithm (LRICR) for interior tomography in microscopic CT at high resolution. In general, the multi-resolution acquisition based methods can be employed to solve the data truncation problem if the project data acquired at low resolution are utilized to fill up the truncated projection data acquired at high resolution. However, most existing methods place quite strict restrictions on the data acquisition geometry, which greatly limits their utility in practice. In the proposed LRICR algorithm, full and partial data acquisition (scan) at low and high resolutions, respectively, are carried out. Using the image reconstructed from sparse projection data acquired at low resolution as the prior, a microscopic image at high resolution is reconstructed from the truncated projection data acquired at high resolution. Two synthesized digital phantoms, a raw bamboo culm and a specimen of mouse femur, were utilized to evaluate and verify performance of the proposed LRICR algorithm. Compared with the conventional TV minimization based algorithm and the multi-resolution scout-reconstruction algorithm, the proposed LRICR algorithm shows significant improvement in reduction of the artifacts caused by data truncation, providing a practical solution for high quality and reliable interior tomography in microscopic CT applications. The proposed LRICR algorithm outperforms the multi-resolution scout-reconstruction method and the TV minimization based reconstruction for interior tomography in microscopic CT.

  12. Hypersensitivity pneumonitis (extrinsic allergic alveolitis): high-resolution computed tomography findings; Pneumonite por hipersensibilidade (alveolite alergica extrinseca): achados na tomografia computadorizada de alta resolucao

    Energy Technology Data Exchange (ETDEWEB)

    Almeida Junior, Jose Guiomar de; Marchiori, Edson [Universidade Federal Fluminense, Niteroi, RJ (Brazil). Faculdade de Ciencias Medicas. Dept. de Radiologia]. E-mail: edmarchiori@zipmail.com.br; Escuissato, Dante L. [Parana Univ., Curitiba, PR (Brazil). Dept. de Radiologia; Souza Junior, Arthur Soares [Faculdade de Medicina de Sao Jose do Rio Preto (FAMERP), SP (Brazil). Dept. de Radiologia; Gasparetto, Emerson L. [Parana Univ., Curitiba, PR (Brazil). Hospital de Clinicas; Nobre, Luiz Felipe [Santa Catarina Univ., Florianopolis, SC (Brazil); Irion, Klaus L. [Santa Casa de Misericordia de Porto Alegre, RS (Brazil). Pavilhao Pereira Filho. Servico de Radiologia

    2003-12-01

    Hypersensitivity pneumonitis, or extrinsic allergic alveolitis, is an immunologic disease of the lungs caused by inhaled chemicals or organics allergens. A lymphocytic inflammatory response in the peripheral airways and surrounding interstitial tissue occurs. In this study the high-resolution computed tomography findings of 13 patients with hypersensitivity pneumonitis were analyzed and discussed. The most frequent high-resolution computed tomography findings were: ground-glass opacities (92.3%), centrilobular nodules (38.4%) and air trapping (38.4%). Other findings included bronchiectasis (23.1%), consolidation (23.1%), crazy paving (7.7%), parenchymal bands (15.4%), linear opacities (7.7%), architectural distortion (7.7%), tracheal dilatation (7.7%), intralobular reticulate (7.7%), honeycombing (7.7%), emphysema (7.7%) and atelectasis (7.7%). In two of the 13 patients there was fibrosis (architectural distortion and honeycombing), which represents the chronic phase of the disease. (author)

  13. Using x-ray computed tomography in hydrology: Systems, resolutions, and limitations

    DEFF Research Database (Denmark)

    Wildenschild, Dorthe; Hopmans, J.W.; Vaz, C.M.P.

    2002-01-01

    media, obtained with different scanning systems and sample sizes, to illustrate advantages and limitations of these various systems, including topics of spatial resolution and contrast. In addition, we present examples of our most recent three-dimensional high-resolution images, for which......A combination of advances in experimental techniques and mathematical analysis has made it possible to characterize phase distribution and pore geometry in porous media using non-destructive X-ray computed tomography (CT). We present qualitative and quantitative CT results for partially saturated...

  14. The demonstration of the auditory ossicles by high resolution CT

    International Nuclear Information System (INIS)

    Lloyd, G.A.S.; Boulay, G.H. du; Phelps, P.D.; Pullicino, P.

    1979-01-01

    The high resolution CT scanning system introduced by EMI in 1978 has added a new dimension to computerised tomography in otology. The apparatus used for this study was an EMI CT 5005 body scanner adapted for head and neck scanning and incorporating a high resolution facility. The latter has proved most advantageous in areas of relatively high differential absorption, so that its application to the demonstration of abnormalities in the petrous temporal bone, and in particular middle ear disease, has been very rewarding. Traumatic ossicular disruptions may now be demonstrated and the high contrast of CT often shows them better than conventional hypocycloidal tomography. The stapes is also better visualised and congenital abnormalities of its superstructure have been recorded. These studies have been achieved with a very acceptable level of radiation to the eye, lens and cornea and the technique is clearly a rival to conventional pluridirectional tomography in the assessment of the petrous temporal bone. With further design improvements high resolution CT could completely replace existing techniques. (orig.) [de

  15. Pneumocystis carinii pneumonia in acquired immunodeficiency syndrome - correlation of high-resolution computed tomography and anatomopathology; Pneumocistose na sindrome da imunodeficiencia adquirida: correlacao da tomografia computadorizada de alta resolucao com a anatomopatologia

    Energy Technology Data Exchange (ETDEWEB)

    Marchiori, Edson; Moreira, Luiza Beatriz [Universidade Federal Fluminense, Niteroi, RJ (Brazil). Dept. de Radiologia]. E-mail: edmarchiori@zipmail.com.br; Capone, Domenico [Universidade do Estado, Rio de Janeiro, RJ (Brazil). Faculdade de Medicina; Moraes, Heleno Pinto de [Universidade Federal Fluminense, Niteroi, RJ (Brazil). Dept. de Patologia; Pereira, Cyntia Inez Guedes Soares

    2001-12-01

    We present the main findings observed on the high-resolution computed tomography examinations of 15 patients with acquired immunodeficiency syndrome and Pneumocystis carinii pneumonia. The high-resolution computed tomography and autopsy findings of 5 patients were also compared. The most frequently observed high-resolution computed tomography patterns were ground-glass attenuation, consolidation areas, crazy-paving pattern and cysts. Nodules and intralobular reticulation were less frequently observed. Ground-glass attenuation and consolidation areas corresponded to alveolar filling with inflammatory exudate. Thickening of the interlobular septa was due to cell infiltration and edema. One patient presented interlobular reticulation, and the pathology study revealed alveolar septa thickening due to cell infiltration and fibrosis. Nodules observed in one of the patients corresponded to a patchy intra alveolar accumulation of microorganisms and inflammatory cells forming a 'granulomatous' pattern. (author)

  16. High Resolution Computed Tomography in Asthma 

    Directory of Open Access Journals (Sweden)

    Nabil Maradny

    2012-03-01

    Full Text Available  Objectives: High-resolution computed tomography (HRCT can detect the structural abnormalities in asthma. This study attempts to correlate these abnormalities with clinical and pulmonary function test (PFT data.Methods: Consecutive stable asthma patients attending Mubarak Al Kabeer Hospital, Kuwait, were subjected to HRCT during a six month period from July 2004 to December 2004, after initial evaluation and PFT.Results: Of the 28 cases, sixteen (57.1�20had moderate, 6 (21.4�20had mild and 6 (21.4�20had severe persistent asthma. Thirteen (46.4�20patients had asthma for 1 to 5 years and 12 (42.9�20were having asthma for >10 years. Bronchial wall thickening (57.1� bronchiectasis (28.6� mucoid impaction (17.9� mosaic attenuation (10.7� air trapping (78.6�20and plate like atelectasis (21.4�20were noted. Bronchial wall thickening (p=0.044 and bronchiectasis (p=0.063 were most prevalent in males. Ten (35.7�20patients exhibited mild, 9 (32.1�20had moderate and 3 (10.7�20had severe air trapping. The difference in Hounsfield units between expiratory and inspiratory slices (air trapping when correlated with percent-predicted FEV1 in right upper (r=0.25;p=0.30, left upper (r=0.20; p=0.41, right mid (r=0.15; p=0.53, left mid (r=-0.04; p=0.60, right lower (r=0.04; p=0.86 and left lower zones (r=-0.13; p=0.58 showed no relation. The same when correlated as above with the percent predicted FEF 25-75 did not show any significant association. The presence of air trapping was compared with sex (p=0.640, nationality (p=1.000, disease duration (p=1.000 and severity of symptoms (p=0.581.Conclusion: Abnormal HRCT findings are common in asthma; however, air trapping when present was not related to the duration or severity of the illness or to the FEV1.

  17. Computerized axial tomography of the chest for visualization of ''absent'' pulmonary arteries

    International Nuclear Information System (INIS)

    Sondheimer, H.M.; Oliphant, M.; Schneider, B.; Kavey, R.E.W.; Blackman, M.S.; Parker, F.B. Jr.

    1982-01-01

    To expand the search for central pulmonary arteries in six patients with absence of cardiac-pulmonary continuity, computerized axial tomography (CAT) of the chest was performed. The CAT scans were compared with previous arteriograms and pulmonary vein wedge angiograms. Three patients with type IV truncus arteriosus were studied, and none had a central, right or left pulmonary artery on CAT scan. However, two patients with tetralogy of Fallot with pulmonary atresia and a patent ductus arteriosus to the right lung demonstrated the presence of a left pulmonary artery. In addition, one child with truncus arteriosus with ''absent'' left pulmonary artery demonstrated a left pulmonary artery on the CAT scan. The CAT scan may therefore enhance our ability to search for disconnected pulmonary arteries in children with complex cyanotic congenital heart disease

  18. Computerized tomography. Fundamentals, equipment, image quality, applications. 2. rev. and enl. ed.

    International Nuclear Information System (INIS)

    Kalender, W.A.

    2006-01-01

    The book provides a clear and user-oriented outline of the theoretical and technical fundamentals of computerized tomography for a wide range of readers, from conventional CT to volume CT with conical beams. Image quality, its relevant influencing parameters and the performance factors to be observed for clinical application are discussed in detail, as are dose requirements, dose metering and dose reduction measures in CT. The second, revised edition contains updated information and also presents new technologies. A CD-ROM with attractive exemplary appications, animations and interactive exercises in image interpretation and manipulation is included. The book addresses everyone concerned with CT, either in their daily routine or even only every now and then, i.e. physicians, medical assistants, engineers, technicians and physicists. The book also contains a glossary of technical terms. (orig.)

  19. Repeatability of Computerized Tomography-Based Anthropomorphic Measurements of Frailty in Patients With Pulmonary Fibrosis Undergoing Lung Transplantation.

    Science.gov (United States)

    McClellan, Taylor; Allen, Brian C; Kappus, Matthew; Bhatti, Lubna; Dafalla, Randa A; Snyder, Laurie D; Bashir, Mustafa R

    To determine interreader and intrareader repeatability and correlations among measurements of computerized tomography-based anthropomorphic measurements in patients with pulmonary fibrosis undergoing lung transplantation. This was an institutional review board-approved, Health Insurance Portability and Accountability Act-compliant retrospective study of 23 randomly selected subjects (19 male and 4 female; median age = 69 years; range: 66-77 years) with idiopathic pulmonary fibrosis undergoing pulmonary transplantation, who had also undergone preoperative thoracoabdominal computerized tomography. Five readers of varying imaging experience independently performed the following cross-sectional area measurements at the inferior endplate of the L3 vertebral body: right and left psoas muscles, right and left paraspinal muscles, total abdominal musculature, and visceral and subcutaneous fat. The following measurements were obtained at the inferior endplate of T6: right and left paraspinal muscles with and without including the trapezius muscles and subcutaneous fat. Three readers repeated all measurements to assess intrareader repeatability. Intrareader repeatability was nearly perfect (interclass correlation coefficients = 0.99, P < 0.001). Interreader agreement was excellent across all 5 readers (interclass correlation coefficients: 0.71-0.99, P < 0.001). Coefficients of variance between measures ranged from 3.2%-6.8% for abdominal measurements, but were higher for thoracic measurements, up to 23.9%. Correlation between total paraspinal and total psoas muscle area was strong (r 2 = 0.67, P < 0.001). Thoracic and abdominal musculature had a weaker correlation (r 2 = 0.35-0.38, P < 0.001). Measures of thoracic and abdominal muscle and fat area are highly repeatable in patients with pulmonary fibrosis undergoing lung transplantation. Measures of muscle area are strongly correlated among abdominal locations, but inversely correlated between abdominal and thoracic locations

  20. Imaging of cellular spread on a three-dimensional scaffold by means of a novel cell-labeling technique for high-resolution computed tomography

    NARCIS (Netherlands)

    Thimm, B.W.; Hofmann, S.; Schneider, P.; Carretta, R.; Müller, R.

    2012-01-01

    Computed tomography (CT) represents a truly three-dimensional (3D) imaging technique that can provide high-resolution images on the cellular level. Thus, one approach to detect single cells is X-ray absorption-based CT, where cells are labeled with a dense, opaque material providing the required

  1. Computerized tomography diagnosis of cartilage destruction in carcinoma of the larynx

    International Nuclear Information System (INIS)

    Kawashima, Osamu; Tomizawa, Yoshio; Yasuoka, Yoshihito; Kamei, Tamio

    1991-01-01

    In 20 cases of laryngeal carcinoma, the pre-operative computerized tomography (CT) films were correlated with the macroscopic appearance of specimens obtained at the time of surgery. A correct diagnosis of cartilage destruction was made by pre-operative CT in 75% of cases in which the thyroid cartilage was involved and in about 79% of those with either arytenoid or cricoid cartilage involvement. A comparison between the pathological findings and the pre-operative CT findings in 9 cases of laryngeal carcinoma with destruction of the thyroid cartilage revealed several pathological changes which may lead to an incorrect CT diagnosis. These changes include microscopic infiltration; destruction of cartilage at the anterior commisure; tumor advance to sites of ossification, especially infiltration into ossifying cartilage located between two areas of non-ossifying cartilage; and infiltration of the tumor within the cartilage with preservation of the perichondrium. (author)

  2. Pulmonary high-resolution computed tomography findings in nephropathia epidemica

    Energy Technology Data Exchange (ETDEWEB)

    Paakkala, Antti, E-mail: antti.paakkala@pshp.fi [Medical Imaging Centre, Tampere University Hospital, 33521 Tampere (Finland); Jaervenpaeae, Ritva, E-mail: ritva.jarvenpaa@pshp.fi [Medical Imaging Centre, Tampere University Hospital, 33521 Tampere (Finland); Maekelae, Satu, E-mail: satu.marjo.makela@uta.fi [Department of Internal Medicine, Tampere University Hospital, 33521 Tampere (Finland); Medical School, University of Tampere, 33521 Tampere (Finland); Huhtala, Heini, E-mail: heini.huhtala@uta.fi [School of Public Health, University of Tampere, 33521 Tampere (Finland); Mustonen, Jukka, E-mail: jukka.mustonen@uta.fi [Department of Internal Medicine, Tampere University Hospital, 33521 Tampere (Finland); Medical School, University of Tampere, 33521 Tampere (Finland)

    2012-08-15

    Purpose: To evaluate lung high-resolution computed tomography (HRCT) findings in patients with Puumala hantavirus-induced nephropathia epidemica (NE), and to determine if these findings correspond to chest radiograph findings. Materials and methods: HRCT findings and clinical course were studied in 13 hospital-treated NE patients. Chest radiograph findings were studied in 12 of them. Results: Twelve patients (92%) showed lung parenchymal abnormalities in HRCT, while only 8 had changes in their chest radiography. Atelectasis, pleural effusion, intralobular and interlobular septal thickening were the most common HRCT findings. Ground-glass opacification (GGO) was seen in 4 and hilar and mediastinal lymphadenopathy in 3 patients. Atelectasis and pleural effusion were also mostly seen in chest radiographs, other findings only in HRCT. Conclusion: Almost every NE patient showed lung parenchymal abnormalities in HRCT. The most common findings of lung involvement in NE can be defined as accumulation of pleural fluid and atelectasis and intralobular and interlobular septal thickening, most profusely in the lower parts of the lung. As a novel finding, lymphadenopathy was seen in a minority, probably related to capillary leakage and overall fluid overload. Pleural effusion is not the prominent feature in other viral pneumonias, whereas intralobular and interlobular septal thickening are characteristic of other viral pulmonary infections as well. Lung parenchymal findings in HRCT can thus be taken not to be disease-specific in NE and HRCT is useful only for scientific purposes.

  3. High-Resolution X-Ray Tomography: A 3D Exploration Into the Skeletal Architecture in Mouse Models Submitted to Microgravity Constraints

    Directory of Open Access Journals (Sweden)

    Alessandra Giuliani

    2018-03-01

    Full Text Available Bone remodeling process consists in a slow building phase and in faster resorption with the objective to maintain a functional skeleton locomotion to counteract the Earth gravity. Thus, during spaceflights, the skeleton does not act against gravity, with a rapid decrease of bone mass and density, favoring bone fracture. Several studies approached the problem by imaging the bone architecture and density of cosmonauts returned by the different spaceflights. However, the weaknesses of the previously reported studies was two-fold: on the one hand the research suffered the small statistical sample size of almost all human spaceflight studies, on the other the results were not fully reliable, mainly due to the fact that the observed bone structures were small compared with the spatial resolution of the available imaging devices. The recent advances in high-resolution X-ray tomography have stimulated the study of weight-bearing skeletal sites by novel approaches, mainly based on the use of the mouse and its various strains as an animal model, and sometimes taking advantage of the synchrotron radiation support to approach studies of 3D bone architecture and mineralization degree mapping at different hierarchical levels. Here we report the first, to our knowledge, systematic review of the recent advances in studying the skeletal bone architecture by high-resolution X-ray tomography after submission of mice models to microgravity constrains.

  4. Ground-glass opacity in diffuse lung diseases: high-resolution computed tomography-pathology correlation

    International Nuclear Information System (INIS)

    Santos, Maria Lucia de Oliveira; Vianna, Alberto Domingues; Marchiori, Edson; Souza Junior, Arthur Soares; Moraes, Heleno Pinto de

    2003-01-01

    Ground-glass opacity is a finding frequently seen in high-resolution computed tomography examinations of the chest and is characterized by hazy increased attenuation of lung, however without blurring of bronchial and vascular margins. Due to its un specificity, association with other radiological, clinical and pathological findings must be considered for an accurate diagnostic interpretation. In this paper were reviewed 62 computed tomography examinations of patients with diffuse pulmonary diseases of 14 different etiologies in which ground-glass opacity was the only or the most remarkable finding, and correlated this findings with pathology abnormalities seen on specimens obtained from biopsies or necropsies. In pneumocystosis, ground-glass opacities correlated histologically with alveolar occupation by a foaming material containing parasites, in bronchiole alveolar cell carcinoma with thickening of the alveolar septa and occupation of the lumen by mucus and tumoral cells, in paracoccidioidomycosis with thickening of the alveolar septa, areas of fibrosis and alveolar bronchopneumonia exudate, in sarcoidosis with fibrosis or clustering of granulomas and in idiopathic pulmonary fibrosis with alveolar septa thickening due to fibrosis. Alveolar occupation by blood was found in cases of leptospirosis, idiopathic hemo siderosis, metastatic kidney tumor and invasive aspergillosis whereas oily vacuole were seen in lipoid pneumonia, proteinaceous and lipo proteinaceous material in silico proteinosis and pulmonary alveolar proteinosis, and edematous fluid in cardiac failure. (author)

  5. Effects of polytetrafluoroethylene treatment and compression on gas diffusion layer microstructure using high-resolution X-ray computed tomography

    Science.gov (United States)

    Khajeh-Hosseini-Dalasm, Navvab; Sasabe, Takashi; Tokumasu, Takashi; Pasaogullari, Ugur

    2014-11-01

    The microstructure of a TGP-H-120 Toray paper gas diffusion layer (GDL) was investigated using high resolution X-ray computed tomography (CT) technique, with a resolution of 1.8 μm and a field of view (FOV) of ∼1.8 × 1.8 mm. The images obtained from the tomography scans were further post processed, and image thresholding and binarization methodologies are presented. The validity of Otsu's thresholding method was examined. Detailed information on bulk porosity and porosity distribution of the GDL at various Polytetrafluoroethylene (PTFE) treatments and uniform/non-uniform compression pressures was provided. A sample holder was designed to investigate the effects of non-uniform compression pressure, which enabled regulating compression pressure between 0, and 3 MPa at a gas channel/current collector rib configuration. The results show the heterogeneous and anisotropic microstructure of the GDL, non-uniform distribution of PTFE, and significant microstructural change under uniform/non-uniform compression. These findings provide useful inputs for numerical models to include the effects of microstructural changes in the study of transport phenomena within the GDL and to increase the accuracy and predictability of cell performance.

  6. Prognosis of the computerized tomography in the severe head injury. Valor pronostico de la tomografia axial computada (TC) en los traumatismos craneoencefalicos severos

    Energy Technology Data Exchange (ETDEWEB)

    Garcia-Nieto, J.J.; Lorenzo Dominguez, M.T.; Martin Sanchez, M.J.; Sanchez Gonzalez, E.

    1991-01-01

    A prospective study is made with sixty five people affected of severe head injury, that is to say, with eight or less points in the Glasgow Coma Scale (GCS), when they get to the hospital. They are studied by computerized tomography at admission, and three and seven days after arrival. In this way, we appraise the type of the lesion, its intensity and the possible prognosis, considering in the last case three features: a) ventricular collapse; b) the mean line structure s shift; and c) effects on perimesencephalic cistern. The findings were parametized and we were able to introduce into the computer program relationships between these findings and the end results. These last ones were appraised through the Glasgow Outcome Scale (GOS). We could show that certain findings in computerized tomography scans have an unavoidable prognosis while as others have a more favorable prognosis. (Author)

  7. Study on beam geometry and image reconstruction algorithm in fast neutron computerized tomography at NECTAR facility

    Science.gov (United States)

    Guo, J.; Bücherl, T.; Zou, Y.; Guo, Z.

    2011-09-01

    Investigations on the fast neutron beam geometry for the NECTAR facility are presented. The results of MCNP simulations and experimental measurements of the beam distributions at NECTAR are compared. Boltzmann functions are used to describe the beam profile in the detection plane assuming the area source to be set up of large number of single neutron point sources. An iterative algebraic reconstruction algorithm is developed, realized and verified by both simulated and measured projection data. The feasibility for improved reconstruction in fast neutron computerized tomography at the NECTAR facility is demonstrated.

  8. Study on beam geometry and image reconstruction algorithm in fast neutron computerized tomography at NECTAR facility

    International Nuclear Information System (INIS)

    Guo, J.; Buecherl, T.; Zou, Y.; Guo, Z.

    2011-01-01

    Investigations on the fast neutron beam geometry for the NECTAR facility are presented. The results of MCNP simulations and experimental measurements of the beam distributions at NECTAR are compared. Boltzmann functions are used to describe the beam profile in the detection plane assuming the area source to be set up of large number of single neutron point sources. An iterative algebraic reconstruction algorithm is developed, realized and verified by both simulated and measured projection data. The feasibility for improved reconstruction in fast neutron computerized tomography at the NECTAR facility is demonstrated.

  9. Study on beam geometry and image reconstruction algorithm in fast neutron computerized tomography at NECTAR facility

    Energy Technology Data Exchange (ETDEWEB)

    Guo, J. [State Key Laboratory of Nuclear Physics and Technology and School of Physics, Peking University, 5 Yiheyuan Lu, Beijing 100871 (China); Lehrstuhl fuer Radiochemie, Technische Universitaet Muenchen, Garching 80748 (Germany); Buecherl, T. [Lehrstuhl fuer Radiochemie, Technische Universitaet Muenchen, Garching 80748 (Germany); Zou, Y., E-mail: zouyubin@pku.edu.cn [State Key Laboratory of Nuclear Physics and Technology and School of Physics, Peking University, 5 Yiheyuan Lu, Beijing 100871 (China); Guo, Z. [State Key Laboratory of Nuclear Physics and Technology and School of Physics, Peking University, 5 Yiheyuan Lu, Beijing 100871 (China)

    2011-09-21

    Investigations on the fast neutron beam geometry for the NECTAR facility are presented. The results of MCNP simulations and experimental measurements of the beam distributions at NECTAR are compared. Boltzmann functions are used to describe the beam profile in the detection plane assuming the area source to be set up of large number of single neutron point sources. An iterative algebraic reconstruction algorithm is developed, realized and verified by both simulated and measured projection data. The feasibility for improved reconstruction in fast neutron computerized tomography at the NECTAR facility is demonstrated.

  10. Value of computerized tomography in the diagnosis of bone and musculoskeletal system tumors of the pelvis and extremities

    International Nuclear Information System (INIS)

    Langer, R.; Langer, M.

    1983-01-01

    49 cases of tumors of the musculoskeletal system of the pelvis and the extremities have been investigated by computerized tomography. The CT was performed only after conventional radiologic methods. The results are discussed and compared with those described in the literature. The advantages and disadvantages of CT of musculoskeletal disorders are discussed. We consider the CT to be of value in disorders of the musculoskeletal system, specially, if operative- or radiotherapy is planned. (orig.) [de

  11. Clinical, endocrinological, and computerized tomography scans for symmetrical calcification of the basal ganglia

    International Nuclear Information System (INIS)

    Goldscheider, H.G.; Lischewski, R.; Claus, D.; Streibl, W.; Waiblinger, G.; Ulm Univ., Schwendi/Dietenbronn; Ulm Univ.

    1980-01-01

    Symmetrical calcification of the basal ganglia was found in 2 promille of 8000 computerized tomography (CT) scans. Of 19 cases, only 2 were detectable on conventional skull films. The less prominent calcifications were most often found in the region of the pallidum, the knee of the internal capsule. Also, the lesions were generally symmetrical. Thus these factors must be considered basic morphological characteristics of the pathophysiological process. Additional neurological disorders were present in 6 patients. Neurological symptoms in the remaining 13, when present, depended on the extent of the lesion. The most common finding was tremor, although disturbances of fine motor control, transient lateralizing signs, and seizures were also noted. No particular constellation of symptoms or signs permitted accurate clinical localization of the lesions. (orig./AJ) [de

  12. TH-AB-209-07: High Resolution X-Ray-Induced Acoustic Computed Tomography

    Energy Technology Data Exchange (ETDEWEB)

    Xiang, L; Tang, S [University of Oklahoma, Norman, OK (United States); Ahmad, M [Stanford University, Palo Alto, CA (United States); Xing, L [Stanford University School of Medicine, Stanford, CA (United States)

    2016-06-15

    Purpose: X-ray radiographic absorption imaging is an invaluable tool in medical diagnostics, biology and materials science. However, the use of conventional CT is limited by two factors: the detection sensitivity to weak absorption material and the radiation dose from CT scanning. The purpose of this study is to explore X-ray induced acoustic computed tomography (XACT), a new imaging modality, which combines X-ray absorption contrast and high ultrasonic resolution to address these challenges. Methods: First, theoretical models was built to analyze the XACT sensitivity to X-ray absorption and calculate the minimal radiation dose in XACT imaging. Then, an XACT system comprised of an ultrashort X-ray pulse, a low noise ultrasound detector and a signal acquisition system was built to evaluate the X-ray induced acoustic signal generation. A piece of chicken bone and a phantom with two golden fiducial markers were exposed to 270 kVp X-ray source with 60 ns exposure time, and the X-ray induced acoustic signal was received by a 2.25MHz ultrasound transducer in 200 positions. XACT images were reconstructed by a filtered back-projection algorithm. Results: The theoretical analysis shows that X-ray induced acoustic signals have 100% relative sensitivity to X-ray absorption, but not to X-ray scattering. Applying this innovative technology to breast imaging, we can reduce radiation dose by a factor of 50 compared with newly FDA approved breast CT. The reconstructed images of chicken bone and golden fiducial marker phantom reveal that the spatial resolution of the built XACT system is 350µm. Conclusion: In XACT, the imaging sensitivity to X-ray absorption is improved and the imaging dose is dramatically reduced by using ultrashort pulsed X-ray. Taking advantage of the high ultrasonic resolution, we can also perform 3D imaging with a single X-ray pulse. This new modality has the potential to revolutionize x-ray imaging applications in medicine and biology.

  13. Early-state damage detection, characterization, and evolution using high-resolution computed tomography

    Science.gov (United States)

    Grandin, Robert John

    Safely using materials in high performance applications requires adequately understanding the mechanisms which control the nucleation and evolution of damage. Most of a material's operational life is spent in a state with noncritical damage, and, for example in metals only a small portion of its life falls within the classical Paris Law regime of crack growth. Developing proper structural health and prognosis models requires understanding the behavior of damage in these early stages within the material's life, and this early-stage damage occurs on length scales at which the material may be considered "granular'' in the sense that the discrete regions which comprise the whole are large enough to require special consideration. Material performance depends upon the characteristics of the granules themselves as well as the interfaces between granules. As a result, properly studying early-stage damage in complex, granular materials requires a means to characterize changes in the granules and interfaces. The granular-scale can range from tenths of microns in ceramics, to single microns in fiber-reinforced composites, to tens of millimeters in concrete. The difficulty of direct-study is often overcome by exhaustive testing of macro-scale damage caused by gross material loads and abuse. Such testing, for example optical or electron microscopy, destructive and further, is costly when used to study the evolution of damage within a material and often limits the study to a few snapshots. New developments in high-resolution computed tomography (HRCT) provide the necessary spatial resolution to directly image the granule length-scale of many materials. Successful application of HRCT with fiber-reinforced composites, however, requires extending the HRCT performance beyond current limits. This dissertation will discuss improvements made in the field of CT reconstruction which enable resolutions to be pushed to the point of being able to image the fiber-scale damage structures and

  14. High-resolution computed tomography findings in pulmonary complications after bone marrow transplantation: iconographic essay

    International Nuclear Information System (INIS)

    Gasparetto, Emerson L.; Ono, Sergio E.; Souza, Carolina A.; Escuissato, Dante L.; Rocha, Gabriela de Melo; Inoue, Cezar; Falavigna, Joao M.; Marchiori, Edson; Universidade Federal, Rio de Janeiro

    2005-01-01

    Bone marrow transplantation has been the treatment of choice for many hematologic diseases. However, pulmonary complications, which may occur in up to 60% of the patients, are the main cause of treatment failure and may be divided in three phases according to the patient's immunity. In the first phase, up to 30 days after the procedure, there is a predominance of non-infectious complications and fungal pneumonia. Viral infections, mainly by cytomegalovirus, are common in the second phase (up to 100 days after bone marrow transplantation). Finally, in the late phase after bone marrow transplantation, non-infectious complications as bronchiolitis obliterans organizing pneumonia and graft-versus-host disease are most commonly seen. The authors present a pictorial essay of the high-resolution computed tomography findings in patients with pulmonary complications after bone marrow transplantation. (author)

  15. Paracoccidioidomycosis: high-resolution computed tomography - anatomo-pathological correlation; Paracoccidioidomicose: correlacao da tomografia computadorizada de alta resolucao com a anatomopatologia

    Energy Technology Data Exchange (ETDEWEB)

    Marchiori, Edson; Muniz, Maria Angelica Soares; Santos, Maria Lucia de Oliveira [Universidade Federal Fluminense, Niteroi, RJ (Brazil). Inst. de Radiologia; Moraes, Heleno Pinto de [Universidade Federal Fluminense, Niteroi, RJ (Brazil). Inst. de Patologia; Capone, Domenico [Universidade do Estado, Rio de Janeiro, RJ (Brazil). Inst. de Pneumologia

    2000-12-01

    We reviewed the high-resolution computed tomography scans of 13 patients with paracoccidioidomycosis and correlated the findings with the anatomo-pathological findings of 5 patients. The most frequent findings observed were thickening of the interlobular septa, emphysema, ground glass areas, thickening of bronchial walls, tracheal dilatation, nodules, cavities and evidence of fibrosing disease such as architectural distortion, parenchymatous bands, spicular pleural thickening, intralobular reticulate and thickening with distortion off the axial interstitium. (author)

  16. Imaging actinic keratosis by high-definition optical coherence tomography. Histomorphologic correlation

    DEFF Research Database (Denmark)

    Boone, Marc A L M; Norrenberg, Sarah; Jemec, Gregor B E

    2013-01-01

    With the continued development of non-invasive therapies for actinic keratosis such as PDT and immune therapies, the non-invasive diagnosis and monitoring become increasingly relevant. High-definition optical coherence tomography is a high-resolution imaging tool, with micrometre resolution in both...... transversal and axial directions, enable to visualize individual cells up to a depth of around 570 μm filling the imaging gap between conventional optical coherence tomography and reflectance confocal microscopy. We sought to determine the feasibility of detecting and grading of actinic keratosis...... by this technique using criteria defined for reflectance confocal microscopy compared to histology. In this pilot study, skin lesions of 17 patients with a histologically proven actinic keratosis were imaged by high-definition optical coherence tomography just before excision and images analysed qualitatively...

  17. Computerized tomography of renal parenchymal disturbance following nephrolithotomy

    International Nuclear Information System (INIS)

    Fukuoka, Hiroshi; Ishizuka, Eiichi; Fukushima, Shuji.

    1983-01-01

    Staghorn calculi were removed by nephrolithotomy with the one-layer interrupted parenchymal suture method designed by Taguchi and renal parenchymal disturbance following the operation were evaluated by computerized tomography. Twenty kidneys in 17 cases were examined pre and postoperatively for changes in the incised and sutured part of the renal parenchyma. The postoperative CT scanning demonstrated the low density areas following enhancement and depression of the parenchyma. These changes were classified into the following 3 patterns: Type I-no changes were observed in the parenchyma, or a linear low density area was found (5 kidneys, 25.0%); type II-a long, narrow strip of low density area was found in accord with the excised and sutured part (5 kidneys, 25.0%); and type III-a wedge-shaped low density area or depression of the parenchyma was found (10 kidneys, 50.0%). The length of the parenchymal incision was analysed with reference to these patterns. The length of type I was significantly shorter than that of type II or III (p<0.05). Th e clamping time of the renal pedicle in type I was also shorter than that in type II and III, but the differences did not reach a statistically significant level. Type II pattern frequently was found shortly after the operation. It is, however, undeniable that type II may tramsform to type III. (J.P.N.)

  18. Alterations found with computerized tomography in newly diagnosed type 2 diabetics

    International Nuclear Information System (INIS)

    Bruna, J.

    1989-01-01

    In 28 newly diagnosed type 2 diabetic patients (insulin-independent), computerized tomography (CT) was used to determine the density of the pancreas and the kidneys, densities of the liver, spleen and blood in the abdominal aorta, and to investigate pathological changes in the tissues mentioned above. The results were correlated with laboratory findings. The following changes were found: decreased density of the pancreas (29.4 H) and the liver (49.1 H) and increased density of the spleen (56.3 H) and blood in the abdominal aorta (43.7 H). The decreased density of the pancreas appears to be connected with disorders of lipoprotein metabolism. The decreased liver density was related to increased energy intake by food and to overweight evaluated by Broc's index. Other CT findings in the newly diagnosed type 2 diabetics (changes in the size of the pancreas, and kidneys, kidney cysts, nephrolithiasis, sclerotic plaques on aorta) were not significant. (author). 2 tabs., 11 refs

  19. Characterization of filters and filtration process using X-ray computerized tomography

    International Nuclear Information System (INIS)

    Maschio, Celio; Arruda, Antonio Celso Fonseca de

    1999-01-01

    The objective of this work is to present the potential of X-Ray computerized tomography as a tool for internal characterization of filters used in the solid-liquid separation, mainly the water filters. Cartridge filters (for industrial and domestic applications) contaminated with glass beads were used. The scanning process was carried out both with and without contaminant in the filter to compare the attenuation coefficient of the clean filter and the contaminated filter. The images showed that is possible the mapping the internal structure of the filters and the distribution of the contaminant, permitting a local analysis, that is not possible through the standard tests used by the manufactures. These standard tests reveal only global characteristics of the filter media. The possibility of application for manufacturing process control was also shown, because the non invasive nature is a important advantage of the technique, which also permitted damage detection in filters submitted to severe operational conditions. (author)

  20. Computerized tomography of pelvic osteomyelitis in patients with spinal cord injuries

    International Nuclear Information System (INIS)

    Firooznia, H.; Rafii, M.; Golimbu, C.; Sokolow, J.

    1983-01-01

    Computerized tomography (CT) was performed in 19 patients with spinal cord injury (SCI) who had large pressure sores and in whom other complications were suspected. CT detected the depth, extent, and degree of undermining of the edges of the pressure sores in 19 of 27 lesions. Conventional radiography detected four cases of pelvic osteomyelitis. CT detected eight additional cases of pelvic osteomyelitis, as well as eight clinically unsuspected peripelvic and intrapelvic abscesses. Technetium-99m bone scanning was not very helpful because of localization in chronic proliferative changes of bone and widespread foci of myositis ossificans, as well as in osteomyelitis. Gallium-67 scanning detected only one of six abscesses. It was not very helpful because of confusion of abscess and osteomyelitis with intense soft tissue swelling and cellulitis, which are often associated with pressure sores in patients with chronic SCI. CT was found to be, by far, the modality of choice for detection of pelvic osteomyelitis and abscess in patients with SCI

  1. The use of computed tomography in brain damage testing

    International Nuclear Information System (INIS)

    De Villiers, J.F.K.

    1980-01-01

    The article deals with the diagnosis of brain damage by the use of computerized tomography - especially referring to the injuries of boxers. Three conditions may be evaluated with computerized tomography: i) fenestration of the septum pellucidum; ii) cortical atrophy; and, iii) cerebral atrophy. It also appears that computerized tomography has a place in the evaluation of injuries sustained in the ring, as well as the detection of accelerated ageing of the brain or atrophy

  2. Development of a multiplexed readout with high position resolution for positron emission tomography

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Sangwon; Choi, Yong [Molecular Imaging Research & Education (MiRe) Laboratory, Department of Electronic Engineering, Sogang University, Seoul 04107 (Korea, Republic of); Kang, Jihoon [Department of Biomedical Engineering, Chonnam National University, Yeosu 550-749 (Korea, Republic of); Jung, Jin Ho [Molecular Imaging Research & Education (MiRe) Laboratory, Department of Electronic Engineering, Sogang University, Seoul 04107 (Korea, Republic of)

    2017-04-01

    Detector signals for positron emission tomography (PET) are commonly multiplexed to reduce the number of digital processing channels so that the system can remain cost effective while also maintaining imaging performance. In this work, a multiplexed readout combining Anger position estimation algorithm and position decoder circuit (PDC) was developed to reduce the number of readout channels by a factor of 24, 96-to-4. The data acquisition module consisted of a TDC (50 ps resolution), 4-channel ADCs (12 bit, 105 MHz sampling rate), 2 GB SDRAM and USB3.0. The performance of the multiplexed readout was assessed with a high-resolution PET detector block composed of 2×3 detector modules, each consisting of an 8×8 array of 1.52×1.52×6 mm{sup 3} LYSO, a 4×4 array of 3×3 mm{sup 2} silicon photomultiplier (SiPM) and 13.4×13.4 mm{sup 2} light guide with 0.7 mm thickness. The acquired flood histogram showed that all 384 crystals could be resolved. The average energy resolution at 511 keV was 13.7±1.6% full-width-at-half-maximum (FWHM) and the peak-to-valley ratios of the flood histogram on the horizontal and vertical lines were 18.8±0.8 and 22.8±1.3, respectively. The coincidence resolving time of a pair of detector blocks was 6.2 ns FWHM. The reconstructed phantom image showed that rods down to a diameter of 1.6 mm could be resolved. The results of this study indicate that the multiplexed readout would be useful in developing a PET with a spatial resolution less than the pixel size of the photosensor, such as a SiPM array.

  3. High resolution multiplexed functional imaging in live embryos (Conference Presentation)

    Science.gov (United States)

    Xu, Dongli; Zhou, Weibin; Peng, Leilei

    2017-02-01

    Fourier multiplexed fluorescence lifetime imaging (FmFLIM) scanning laser optical tomography (FmFLIM-SLOT) combines FmFLIM and Scanning laser optical tomography (SLOT) to perform multiplexed 3D FLIM imaging of live embryos. The system had demonstrate multiplexed functional imaging of zebrafish embryos genetically express Foster Resonant Energy Transfer (FRET) sensors. However, previous system has a 20 micron resolution because the focused Gaussian beam diverges quickly from the focused plane, makes it difficult to achieve high resolution imaging over a long projection depth. Here, we present a high-resolution FmFLIM-SLOT system with achromatic Bessel beam, which achieves 3 micron resolution in 3D deep tissue imaging. In Bessel-FmFLIM-SLOT, multiple laser excitation lines are firstly intensity modulated by a Michelson interferometer with a spinning polygon mirror optical delay line, which enables Fourier multiplexed multi-channel lifetime measurements. Then, a spatial light modulator and a prism are used to transform the modulated Gaussian laser beam to an achromatic Bessel beam. The achromatic Bessel beam scans across the whole specimen with equal angular intervals as sample rotated. After tomography reconstruction and the frequency domain lifetime analysis method, both the 3D intensity and lifetime image of multiple excitation-emission can be obtained. Using Bessel-FmFLIM-SLOT system, we performed cellular-resolution FLIM tomography imaging of live zebrafish embryo. Genetically expressed FRET sensors in these embryo will allow non-invasive observation of multiple biochemical processes in vivo.

  4. South Ilan Plain High-Resolution 3-D S-Wave Velocity from Ambient Noise Tomography

    Directory of Open Access Journals (Sweden)

    Kai-Xun Chen

    2016-06-01

    Full Text Available The Ilan Plain in northeastern Taiwan is located at a pivotal point where the Ryukyu trench subduction zone, the northern Taiwan crustal stretching zone, and the ongoing arc-continent collision zone converge. In contrast to the North Ilan Plain, the South Ilan Plain exhibits a thin unconsolidated sedimentary layer with depths ranging from 0 - 1 km, high on-land seismicity and significant SE movements relative to Penghu island. We deployed a dense network of 43 short-period vertical component Texan instruments from June to November 2013 in this study, covering most of the South Ilan Plain and its vicinity. We then used the ambient noise tomography method for simultaneous phase and group Rayleigh wave velocity measurements to invert a high-resolution 3-D S-wave for shallow structures (up to a depth of 2.5 km in the South Ilan Plain. We used the fast marching method for ray tracing to deal with ray bending in an inhomogeneous medium. The resulting rays gradually bend toward high velocity zones with increasing number of iterations. The high velocity zone results are modified by more iterations and the resolutions become higher because ray crossings are proportional to ray densities for evenly distributed stations. The final results agreed well with known sedimentary basement thickness patterns. We observed nearly EW trending fast anomalies beneath the mountainous terrain abutting to the South Ilan Plain. The Chingshui location consistently exhibited a low S-wave velocity zone to a depth of 1.5 km.

  5. X-ray phase-contrast tomography for high-spatial-resolution zebrafish muscle imaging

    Science.gov (United States)

    Vågberg, William; Larsson, Daniel H.; Li, Mei; Arner, Anders; Hertz, Hans M.

    2015-11-01

    Imaging of muscular structure with cellular or subcellular detail in whole-body animal models is of key importance for understanding muscular disease and assessing interventions. Classical histological methods for high-resolution imaging methods require excision, fixation and staining. Here we show that the three-dimensional muscular structure of unstained whole zebrafish can be imaged with sub-5 μm detail with X-ray phase-contrast tomography. Our method relies on a laboratory propagation-based phase-contrast system tailored for detection of low-contrast 4-6 μm subcellular myofibrils. The method is demonstrated on 20 days post fertilization zebrafish larvae and comparative histology confirms that we resolve individual myofibrils in the whole-body animal. X-ray imaging of healthy zebrafish show the expected structured muscle pattern while specimen with a dystrophin deficiency (sapje) displays an unstructured pattern, typical of Duchenne muscular dystrophy. The method opens up for whole-body imaging with sub-cellular detail also of other types of soft tissue and in different animal models.

  6. A comparative study of noise in supercontinuum light sources for ultra-high resolution optical coherence tomography

    DEFF Research Database (Denmark)

    Maria J., Sanjuan-Ferrer,; Bravo Gonzalo, Ivan; Bondu, Magalie

    2017-01-01

    Supercontinuum (SC) light is a well-established technology, which finds applications in several domains ranging from chemistry to material science and imaging systems [1-2]. More specifically, its ultra-wide optical bandwidth and high average power make it an ideal tool for Optical Coherence...... Tomography (OCT). Over the last 5 years, numerous examples have demonstrated its high potential [3-4] in this context. However, SC light sources present pulse-to-pulse intensity variation that can limit the performance of any OCT system [5] by degrading their signal to noise ratio (SNR). To this goal, we...... have studied and compared the noise of several SC light sources and evaluated how their noise properties affect the performance of Ultra-High Resolution OCT (UHR-OCT) at 1300 nm. We have measured several SC light sources with different parameters (pulse length, energy, seed repetition rate, etc.). We...

  7. High-resolution optical coherence tomography, autofluorescence, and infrared reflectance imaging in Sjögren reticular dystrophy.

    Science.gov (United States)

    Schauwvlieghe, Pieter-Paul; Torre, Kara Della; Coppieters, Frauke; Van Hoey, Anneleen; De Baere, Elfride; De Zaeytijd, Julie; Leroy, Bart P; Brodie, Scott E

    2013-01-01

    To describe the phenotype of three cases of Sjögren reticular dystrophy in detail, including high-resolution optical coherence tomography, autofluorescence imaging, and near-infrared reflectance imaging. Two unrelated teenagers were independently referred for ophthalmologic evaluation. Both underwent a full ophthalmologic workup, including electrophysiologic and extensive imaging with spectral-domain optical coherence tomography, autofluorescence imaging, and near-infrared reflectance imaging. In addition, mutation screening of ABCA4, PRPH2, and the mitochondrial tRNA gene was performed in Patient 1. Subsequently, the teenage sister of Patient 2 was examined. Strikingly similar phenotypes were present in these three patients. Fundoscopy showed bilateral foveal pigment alterations, and a lobular network of deep retinal, pigmented deposits throughout the posterior pole, tapering toward the midperiphery, with relative sparing of the immediate perifoveal macula and peripapillary area. This network is mildly to moderately hyperautofluorescent on autofluorescence and bright on near-infrared reflectance imaging. Optical coherence tomography showed abnormalities of the retinal pigment epithelium-Bruch membrane complex, photoreceptor outer segments, and photoreceptor inner/outer segment interface. The results of retinal function test were entirely normal. No molecular cause was detected in Patient 1. Imaging suggested that the lobular network of deep retinal deposits in Sjögren reticular dystrophy is the result of accumulation of both pigment and lipofuscin between photoreceptors and retinal pigment epithelium, as well as within the retinal pigment epithelium.

  8. Development of a large-area Multigap RPC with adequate spatial resolution for muon tomography

    Science.gov (United States)

    Wang, J.; Wang, Y.; Wang, X.; Zeng, M.; Xie, B.; Han, D.; Lyu, P.; Wang, F.; Li, Y.

    2016-11-01

    We study the performance of a large-area 2-D Multigap Resistive Plate Chamber (MRPC) designed for muon tomography with high spatial resolution. An efficiency up to 98% and a spatial resolution of around 270 μ m are obtained in cosmic ray and X-ray tests. The performance of the MRPC is also investigated for two working gases: standard gas and pure Freon. The result shows that the MRPC working in pure Freon can provide higher efficiency and better spatial resolution.

  9. Pulmonary malaria: high-resolution computed tomography findings - a case report; Malaria pulmonar: aspectos na tomografia computadorizada de alta resolucao - relato de caso

    Energy Technology Data Exchange (ETDEWEB)

    Rodrigues, Rosana; Souza, Daniel Andrade Tinoco de [Universidade Federal, Rio de Janeiro, RJ (Brazil). Hospital Universitario Clementino Fraga Filho. Servico de Radiodiagnostico; Hospital Copa D' Or, Rio de Janeiro, RJ (Brazil); Marchiori, Edson [Universidade Federal Fluminense, Niteroi, RJ (Brazil). Dept. de Radiologia]. E-mail: edmarchiori@bol.com.br

    2004-04-01

    We report the case of a 38-year-old man with pulmonary malaria. High-resolution computed tomography showed thickening of the peribronchovascular interstitium and interlobular septa, areas of consolidation and ground glass attenuation and bilateral pleural effusion suggesting pulmonary edema. The patient recovered well after receiving specific treatment and was discharged after 11 days of hospitalization. (author)

  10. High-speed X-ray phase tomography with Talbot interferometer and fringe scanning method

    International Nuclear Information System (INIS)

    Kibayashi, Shunsuke; Harasse, Sébastien; Yashiro, Wataru; Momose, Atsushi

    2012-01-01

    High-speed X-ray phase tomography based on the Fourier-transform method has been demonstrated with an X-ray Talbot interferometer using white synchrotron radiation. We report the experimental results of high-speed X-ray phase tomography with fringe-scanning method instead of Fourier-transform method to improve spatial resolution without a considerable increase of scan time. To apply fringe-scanning method to high speed tomography, we tested a scan that is a synchronous combination of one-way continuous movements of the sample rotation and the grating displacement. When this scanning method was combined with X-ray phase tomography, we were able to obtain a scan time of 5 s. A comparison of the image quality derived with the conventional approach and with the proposed approach using the fringe-scanning method showed that the latter had better spatial resolution.

  11. Metastatic pulmonary calcification: high-resolution computed tomography findings in 23 cases

    Directory of Open Access Journals (Sweden)

    Luciana Camara Belém

    Full Text Available Abstract Objective: The aim of this study was to evaluate the high-resolution computed tomography (HRCT findings in patients diagnosed with metastatic pulmonary calcification (MPC. Materials and Methods: We retrospectively reviewed the HRCT findings from 23 cases of MPC [14 men, 9 women; mean age, 54.3 (range, 26-89 years]. The patients were examined between 2000 and 2014 in nine tertiary hospitals in Brazil, Chile, and Canada. Diagnoses were established by histopathologic study in 18 patients and clinical-radiological correlation in 5 patients. Two chest radiologists analyzed the images and reached decisions by consensus. Results: The predominant HRCT findings were centrilobular ground-glass nodules (n = 14; 60.9%, consolidation with high attenuation (n = 10; 43.5%, small dense nodules (n = 9; 39.1%, peripheral reticular opacities associated with small calcified nodules (n = 5; 21.7%, and ground-glass opacities without centrilobular ground-glass nodular opacity (n = 5; 21.7%. Vascular calcification within the chest wall was found in four cases and pleural effusion was observed in five cases. The abnormalities were bilateral in 21 cases. Conclusion: MPC manifested with three main patterns on HRCT, most commonly centrilobular ground-glass nodules, often containing calcifications, followed by dense consolidation and small solid nodules, most of which were calcified. We also described another pattern of peripheral reticular opacities associated with small calcified nodules. These findings should suggest the diagnosis of MPC in the setting of hypercalcemia.

  12. Metastatic pulmonary calcification: high-resolution computed tomography findings in 23 cases

    Energy Technology Data Exchange (ETDEWEB)

    Belem, Luciana Camara; Souza, Carolina A.; Souza Junior, Arthur Soares; Escuissato, Dante Luiz; Hochhegger, Bruno; Nobre, Luiz Felipe; Rodrigues, Rosana Souza; Gomes, Antonio Carlos Portugal; Silva, Claudio S.; Guimaraes, Marcos Duarte; Zanetti, Glaucia; Marchiori, Edson, E-mail: edmarchiori@gmail.com [Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ (Brazil); Ottawa Hospital Research Institute, University of Ottawa, (Canada); Faculdade de Medicina de Sao Jose do Rio Preto (FAMERP), SP (Brazil); Ultra X, Sao Jose do Rio Preto, SP (Brazil); Universidade Federal do Parana (UFPR), Curitiba, PR (Brazil); Universidade Federal de Ciencias da Saude de Porto Alegre (UFCSPA), Porto Alegre, RS (Brazil); Universidade Federal de Santa Catarina (UFSC), Florianopolis, SC (Brazil). Hospital Universitario

    2017-07-15

    Objective: The aim of this study was to evaluate the high-resolution computed tomography (HRCT) findings in patients diagnosed with metastatic pulmonary calcification (MPC). Materials and Methods: We retrospectively reviewed the HRCT findings from 23 cases of MPC [14 men, 9 women; mean age, 54.3 (range, 26-89) years]. The patients were examined between 2000 and 2014 in nine tertiary hospitals in Brazil, Chile, and Canada. Diagnoses were established by histopathologic study in 18 patients and clinical-radiological correlation in 5 patients. Two chest radiologists analyzed the images and reached decisions by consensus. Results: The predominant HRCT findings were centrilobular ground-glass nodules (n = 14; 60.9%), consolidation with high attenuation (n = 10; 43.5%), small dense nodules (n = 9; 39.1%), peripheral reticular opacities associated with small calcified nodules (n = 5; 21.7%), and ground-glass opacities without centrilobular ground-glass nodular opacity (n = 5; 21.7%). Vascular calcification within the chest wall was found in four cases and pleural effusion was observed in five cases. The abnormalities were bilateral in 21 cases. Conclusion: MPC manifested with three main patterns on HRCT, most commonly centrilobular ground-glass nodules, often containing calcifications, followed by dense consolidation and small solid nodules, most of which were calcified. We also described another pattern of peripheral reticular opacities associated with small calcified nodules. These findings should suggest the diagnosis of MPC in the setting of hypercalcemia. (author)

  13. Metastatic pulmonary calcification: high-resolution computed tomography findings in 23 cases

    International Nuclear Information System (INIS)

    Belem, Luciana Camara; Souza, Carolina A.; Souza Junior, Arthur Soares; Escuissato, Dante Luiz; Hochhegger, Bruno; Nobre, Luiz Felipe; Rodrigues, Rosana Souza; Gomes, Antonio Carlos Portugal; Silva, Claudio S.; Guimaraes, Marcos Duarte; Zanetti, Glaucia; Marchiori, Edson; Ottawa Hospital Research Institute, University of Ottawa,; Faculdade de Medicina de Sao Jose do Rio Preto; Ultra X, Sao Jose do Rio Preto, SP; Universidade Federal do Parana; Universidade Federal de Ciencias da Saude de Porto Alegre; Universidade Federal de Santa Catarina

    2017-01-01

    Objective: The aim of this study was to evaluate the high-resolution computed tomography (HRCT) findings in patients diagnosed with metastatic pulmonary calcification (MPC). Materials and Methods: We retrospectively reviewed the HRCT findings from 23 cases of MPC [14 men, 9 women; mean age, 54.3 (range, 26-89) years]. The patients were examined between 2000 and 2014 in nine tertiary hospitals in Brazil, Chile, and Canada. Diagnoses were established by histopathologic study in 18 patients and clinical-radiological correlation in 5 patients. Two chest radiologists analyzed the images and reached decisions by consensus. Results: The predominant HRCT findings were centrilobular ground-glass nodules (n = 14; 60.9%), consolidation with high attenuation (n = 10; 43.5%), small dense nodules (n = 9; 39.1%), peripheral reticular opacities associated with small calcified nodules (n = 5; 21.7%), and ground-glass opacities without centrilobular ground-glass nodular opacity (n = 5; 21.7%). Vascular calcification within the chest wall was found in four cases and pleural effusion was observed in five cases. The abnormalities were bilateral in 21 cases. Conclusion: MPC manifested with three main patterns on HRCT, most commonly centrilobular ground-glass nodules, often containing calcifications, followed by dense consolidation and small solid nodules, most of which were calcified. We also described another pattern of peripheral reticular opacities associated with small calcified nodules. These findings should suggest the diagnosis of MPC in the setting of hypercalcemia. (author)

  14. Image processor for high resolution video

    International Nuclear Information System (INIS)

    Pessoa, P.P.; Assis, J.T.; Cardoso, S.B.; Lopes, R.T.

    1989-01-01

    In this paper, we discuss an image presentation and processing system developed in Turbo Pascal 5.0 Language. Our system allows the visualization and processing of images in 16 different colors, taken at a time from a set of 64 possible ones. Digital filters of the mean, mediam Laplacian, gradient and histograms equalization type have been implemented, so as to allow a better image quality. Possible applications of our system are also discussed e.g., satellites, computerized tomography, medicine, microscopes. (author) [pt

  15. Intellectual function, activities of daily living and computerized tomography of the brain in geriatric demented patients

    Energy Technology Data Exchange (ETDEWEB)

    Omura, Fumiaki; Ogura, Chikara; Kishimoto, Akira; Okubo, Masayo; Imamoto, Atsushi [Tottori Univ., Yonago (Japan). School of Medicine; Tsuchie, Harutaka; Sugihara, Kanichiro; Fujii, Shozo

    1984-09-01

    Thirty eight patients of geriatric dementia (mean age 74.9 years) were examined by computerized tomography (CT) and their intellectual functions and activities of daily living (ADL) were evaluated. CT was evaluated by both visual assessment method and direct measuring method. Intellectual function was evaluated by Jikei University dementia rating scale. ADL was evaluated by both Hasegawa's rating scale and Sengoku's rating scale. Results were as follows: significant influence by age was observed in intellectual functions and ADL of subjects above 75 years old. There were good correlations between the higher intellectual function, the better grooming and hygiene, and less needs of nursing care. The severe brain atrophy evaluated by the visual assessment method was correlated with the depressed level of intellectual function. When brain atrophy is mild despite high degree of dementia, reexamination should be made to explore somatic diseases inducing depression of mental activity. It also should be noted that sex and age difference is important in studying geriatric patients.

  16. Intellectual function, activities of daily living and computerized tomography of the brain in geriatric demented patients

    International Nuclear Information System (INIS)

    Omura, Fumiaki; Ogura, Chikara; Kishimoto, Akira; Okubo, Masayo; Imamoto, Atsushi; Tsuchie, Harutaka; Sugihara, Kanichiro; Fujii, Shozo.

    1984-01-01

    Thirty eight patients of geriatric dementia (mean age 74.9 years) were examined by computerized tomography (CT) and their intellectual functions and activities of daily living (ADL) were evaluated. CT was evaluated by both visual assessment method and direct measuring method. Intellectual function was evaluated by Jikei University dementia rating scale. ADL was evaluated by both Hasegawa's rating scale and Sengoku's rating scale. Results were as follows: significant influence by age was observed in intellectual functions and ADL of subjects above 75 years old. There were good correlations between the higher intellectual function, the better grooming and hygiene, and less needs of nursing care. The severe brain atrophy evaluated by the visual assessment method was correlated with the depressed level of intellectual function. When brain atrophy is mild despite high degree of dementia, reexamination should be made to explore somatic diseases inducing depression of mental activity. It also should be noted that sex and age difference is important in studying geriatric patients. (author)

  17. Computerized tomography of the otic capsule and otoliths in the oyster toadfish, Opsanus tau.

    Science.gov (United States)

    Edds-Walton, Peggy L; Arruda, Julie; Fay, Richard R; Ketten, Darlene R

    2015-02-01

    The neurocranium of the toadfish (Opsanus tau) exhibits a distinct translucent region in the otic capsule (OC) that may have functional significance for the auditory pathway. This study used ultrahigh resolution computerized tomography (100 µm voxels) to compare the relative density of three sites along the OC (dorsolateral, midlateral, and ventromedial) and two reference sites (dorsal: supraoccipital crest; ventral: parasphenoid bone) in the neurocranium. Higher attenuation occurs where structural density is greater; thus, we compared the X-ray attenuations measured, which provided a measure of relative density. The maximum attenuation value was recorded for each of the five sites (x and y) on consecutive sections throughout the OC and for each of the three calcareous otoliths associated with the sensory maculae (lagena, saccule, and utricle) in the OC. All three otoliths had higher attenuations than any sites in the neurocranium. Both dorsal and ventral reference sites (supraoccipital crest and parasphenoid bone, respectively) had attenuation levels consistent with calcified bone and had relatively small, irregular variations along the length of the OC in all individuals. The lowest relative attenuations (lowest densities) occurred consistently at the three sites along the OC. In addition, the lowest attenuations measured along the OC occurred at the ventromedial site around the saccular otolith for all seven fish. The decrease in bone density along the OC is consistent with the hypothesis that there is a low-density channel in the skull to facilitate transmission of acoustic stimuli to the auditory endorgans of the ear. © 2014 Wiley Periodicals, Inc.

  18. New microfocus bremsstrahlung source based on betatron B-18 for high-resolution radiography and tomography

    Science.gov (United States)

    Rychkov, M. M.; Kaplin, V. V.; Malikov, E. L.; Smolyanskiy, V. A.; Stepanov, I. B.; Lutsenko, A. S.; Gentsel'man, V.; Vas'kovskiy, I. K.

    2018-01-01

    New microfocus source of hard bremsstrahlung (photon energy > 1 MeV), based on the betatron B-18 with a narrow Ta target inside, for high-resolution radiography and tomography is presented. The first studies of the source demonstrate its possibilities for practical applications to detect the microdefects in products made from heavy materials and to control gaps in joints of parts of composite structures of engineering facilities. The radiography method was used to investigate a compound object consisting of four vertically arranged steel bars between which surfaces were exposed gaps of 10 μm in width. The radiographic image of the object, obtained with a magnification of 2.4, illustrates the good sensitivity of detecting the gaps between adjacent bars, due to the small width of the linear focus of the bremsstrahlung source.

  19. In vivo monitoring laser tissue interaction using high resolution Fourier-domain optical coherence tomography

    Science.gov (United States)

    Jo, Hang Chan; Shin, Dong Jun; Ahn, Jin-Chul; Chung, Phil-Sang; Kim, DaeYu

    2017-02-01

    Laser-induced therapies include laser ablation to remove or cut target tissue by irradiating high-power focused laser beam. These laser treatments are widely used tools for minimally invasive surgery and retinal surgical procedures in clinical settings. In this study, we demonstrate laser tissue interaction images of various sample tissues using high resolution Fourier-domain optical coherence tomography (Fd-OCT). We use a Q-switch diode-pumped Nd:YVO4 nanosecond laser (532nm central wavelength) with a 4W maximum output power at a 20 kHz repetition rate to ablate in vitro and in vivo samples including chicken breast and mouse ear tissues. The Fd-OCT system acquires time-series Bscan images at the same location during the tissue ablation experiments with 532nm laser irradiation. The real-time series of OCT cross-sectional (B-scan) images compare structural changes of 532nm laser ablation using same and different laser output powers. Laser tissue ablation is demonstrated by the width and the depth of the tissue ablation from the B-scan images.

  20. Regional myocardial perfusion assessed by N-13 labeled ammonia and positron emission computerized axial tomography

    International Nuclear Information System (INIS)

    Schelbert, H.R.; Phelps, M.E.; Hoffman, E.J.; Huang, S.C.; Selin, C.E.; Kuhl, D.E.

    1978-01-01

    The usefulness of 13 NH 3 as an indicator of regional myocardial perfusion suitable for positron emission computerized axial tomography (PCT) has been suggested. However, the relationship between myocardial blood flow and uptake of 13 NH 3 has not been examined quantitatively. It was therefore the purpose of the current investigation to quantitate the relationship of myocardial 13 NH 3 tissue concentration to myocardial blood flow and to examine its suitability for PCT imaging. Twelve open chest dogs were studied. In 8 of the dogs 25 imaging procedures with 13 NH 3 and PCT were performed. In the remaining four dogs the relationship between flow and myocardial 13 NH 3 tissue concentration was assessed by in vitro techniques. The PCT technique provided high quality cross-sectional images of the distribution of 13 NH 3 in left ventricular myocardium. No significant redistribution of 13 NH 3 in myocardium occurred with time. Alterations in regional myocardial blood flow resulted in changes of the regional distribution of 13 NH 3 that were readily appreciated on the PCT images

  1. High-resolution computed tomography findings in chronic eosinophilic vs. cryptogenic organising pneumonia.

    Science.gov (United States)

    Mehrian, P; Doroudinia, A; Rashti, A; Aloosh, O; Dorudinia, A

    2017-11-01

    The similar clinical and computed tomography (CT) characteristics of cryptogenic organising pneumonia (COP) and chronic eosinophilic pneumonia (CEP) make precise diagnosis challenging. To help differentiate between COP and CEP using high-resolution CT (HRCT). Clinical data and HRCT images of COP and CEP patients referred to Masih Daneshvari Hospital, Tehran, Iran, from 2007 to 2015 were reviewed. Diagnosis of COP or CEP was confirmed using open lung biopsy or a combination of transbronchial biopsy, bronchoalveolar lavage fluid (BALF) analysis, peripheral eosinophilia and a favourable response to corticosteroids. Ground-glass opacity, a dominant ground-glass pattern, upper-lobe pneumonia, increased thickness of bronchial walls and a mosaic pattern in the lungs were more frequent in CEP. Lower-lobe pneumonia, subpleural reticulation, a dominant consolidation pattern, nodules and masses, non-septal linear opacities, bronchial dilation and a reverse halo sign were more frequent in COP. History of asthma, wheezing and peripheral eosinophilia was significantly more common in CEP than in COP. Distinguishing between CEP and COP based on HRCT alone is not always possible. However, in many cases, especially if the correct diagnosis cannot be established by other means, certain HRCT features can be very helpful.

  2. Three-dimensional reconstruction and modeling of middle ear biomechanics by high-resolution computed tomography and finite element analysis.

    Science.gov (United States)

    Lee, Chia-Fone; Chen, Peir-Rong; Lee, Wen-Jeng; Chen, Jyh-Horng; Liu, Tien-Chen

    2006-05-01

    To present a systematic and practical approach that uses high-resolution computed tomography to derive models of the middle ear for finite element analysis. This prospective study included 31 subjects with normal hearing and no previous otologic disorders. Temporal bone images obtained from 15 right ears and 16 left ears were used for evaluation and reconstruction. High-resolution computed tomography of temporal bone was performed using simultaneous acquisition of 16 sections with a collimated slice thickness of 0.625 mm. All images were transferred to an Amira visualization system for three-dimensional reconstruction. The created three-dimensional model was translated into two commercial modeling packages, Patran and ANSYS, for finite element analysis. The characteristic dimensions of the model were measured and compared with previously published histologic section data. This result confirms that the geometric model created by the proposed method is accurate except that the tympanic membrane is thicker than when measured by the histologic section method. No obvious difference in the geometrical dimension between right and left ossicles was found (P > .05). The three-dimensional model created by finite element method and predicted umbo and stapes displacements are close to the bounds of the experimental curves of Nishihara's, Huber's, Gan's, and Sun's data across the frequency range of 100 to 8000 Hz. The model includes a description of the geometry of the middle ear components and dynamic equations of vibration. The proposed method is quick, practical, low-cost, and, most importantly, noninvasive as compared with histologic section methods.

  3. Measuring irradiated lung and heart area in breast tangential fields using a simulator-based computerized tomography device

    International Nuclear Information System (INIS)

    Mallik, Raj; Fowler, Allan; Hunt, Peter

    1995-01-01

    Purpose: To illustrate the use of a simulator based computerized tomography system (SIMCT) in the simulation and planning of tangential breast fields. Methods and Materials: Forty-five consecutive patients underwent treatment planning using a radiotherapy simulator with computerized tomography attachment. One to three scans were obtained for each patient, calculations were made on the central axis scan. Due to the wide aperture of this system all patients were able to be scanned in the desired treatment position with arm abducted 90 deg. . Using available software tools the area of lung and/or heart included within the tangential fields was calculated. The greatest perpendicular distance (GPD) from the chest wall to posterior field edge was also measured. Results: The mean GPD for the group was 25.40 mm with 71% of patients having GPDs of ≤ 30 mm. The mean area of irradiated lung was 1780 sq mm which represented 18.0% of the total ipsilateral lung area seen in the central axis. Seven of the patients with left sided tumors had an average 1314 sq mm heart irradiated in the central axis. This represented 11.9% of total heart area in these patients. Conclusion: Measurements of irradiated lung and heart area can be easily and accurately made using a SIMCT device. Such measurements may help identify those patients potentially at risk for lung or heart toxicity as a consequence of their treatment. A major advantage of this device is the ability to scan patients in the actual treatment position

  4. Measuring irradiated lung and heart area in breast tangential fields using a simulator-based computerized tomography device

    Energy Technology Data Exchange (ETDEWEB)

    Mallik, Raj; Fowler, Allan; Hunt, Peter

    1995-01-15

    Purpose: To illustrate the use of a simulator based computerized tomography system (SIMCT) in the simulation and planning of tangential breast fields. Methods and Materials: Forty-five consecutive patients underwent treatment planning using a radiotherapy simulator with computerized tomography attachment. One to three scans were obtained for each patient, calculations were made on the central axis scan. Due to the wide aperture of this system all patients were able to be scanned in the desired treatment position with arm abducted 90 deg. . Using available software tools the area of lung and/or heart included within the tangential fields was calculated. The greatest perpendicular distance (GPD) from the chest wall to posterior field edge was also measured. Results: The mean GPD for the group was 25.40 mm with 71% of patients having GPDs of {<=} 30 mm. The mean area of irradiated lung was 1780 sq mm which represented 18.0% of the total ipsilateral lung area seen in the central axis. Seven of the patients with left sided tumors had an average 1314 sq mm heart irradiated in the central axis. This represented 11.9% of total heart area in these patients. Conclusion: Measurements of irradiated lung and heart area can be easily and accurately made using a SIMCT device. Such measurements may help identify those patients potentially at risk for lung or heart toxicity as a consequence of their treatment. A major advantage of this device is the ability to scan patients in the actual treatment position.

  5. Contribution of computerized tomography and nuclear magnetic resonance to the diagnosis of vascular dementia

    Energy Technology Data Exchange (ETDEWEB)

    Gallois, P; Pruvo, J P

    1987-06-18

    Nuclear magnetic resonance (NMR) and computerized tomography (CT) have become indispensable to the exploration of patients with vascular dementia. NMR is remarkable for its innocuity, its anatomical accuracy, its sensitivity and the three-dimensional approach it offers. CT is less sensitive, but the examinations are shorter and less costly. These two techniques seem to be about equally effective in visualizing multiple infarcts, although NMR gives a better contrast. In dementia due to multiple infarcts, the bilateral cortical and subcortical lesions coexist with moderate cortical atrophy. The cerebral lacunae of lacunar dementia are better visualized by NMR; they are distributed on both sides, predominate in the frontal lobes and only produce slight cortical atrophy, less pronounced than ventricular dilatation. The main advantage of NMR is its high sensitivity in detecting early changes in the white matter, changes which are particularly perceptible in juxta- and peri-ventricular areas in arteriosclerous subcortical leucoencephalopathy. NMR, not very specific here, does not readily separate these lesions from those of other types of leucoencephalopathy. The finding of hypodense areas at CT or hypersignals at NMR (T2) around the ventricles may help in differentiating between vascular dementia, irrespective of its mechanism, and primary dementia.

  6. High-resolution emission tomography of small laboratory animals: physics and gamma-astronomy meet molecular biology

    International Nuclear Information System (INIS)

    Beekman, F.J.; Colijn, A.P.; Vastenhouw, B.; Wiegant, V.M.; Gerrits, M.A.F.M.

    2003-01-01

    Molecular imaging can be defined as the characterization and measurement of biological processes in living animals, model systems and humans at the cellular and molecular level using remote imaging detectors. An example concerns the mapping of the distributions of radioactively labeled molecules in laboratory animals which is of crucial importance for life sciences. Tomographic methods like Single Photon Emission Computed Tomography (SPECT) offer a possibility to visualize distributions of radioactively labeled molecules in living animals. Miniature tomography systems, derived from their clinical counterparts, but with a much higher image resolution are under development in several institutes. An example is U-SPECT that will be discussed in the present paper. Such systems are expected to accelerate several biomedical research procedures, the understanding of gene and protein function, as well as pharmaceutical development

  7. Diagnostic accuracy of cone-beam computed tomography scans with high- and low-resolution modes for the detection of root perforations.

    Science.gov (United States)

    Shokri, Abbas; Eskandarloo, Amir; Norouzi, Marouf; Poorolajal, Jalal; Majidi, Gelareh; Aliyaly, Alireza

    2018-03-01

    This study compared the diagnostic accuracy of cone-beam computed tomography (CBCT) scans obtained with 2 CBCT systems with high- and low-resolution modes for the detection of root perforations in endodontically treated mandibular molars. The root canals of 72 mandibular molars were cleaned and shaped. Perforations measuring 0.2, 0.3, and 0.4 mm in diameter were created at the furcation area of 48 roots, simulating strip perforations, or on the external surfaces of 48 roots, simulating root perforations. Forty-eight roots remained intact (control group). The roots were filled using gutta-percha (Gapadent, Tianjin, China) and AH26 sealer (Dentsply Maillefer, Ballaigues, Switzerland). The CBCT scans were obtained using the NewTom 3G (QR srl, Verona, Italy) and Cranex 3D (Soredex, Helsinki, Finland) CBCT systems in high- and low-resolution modes, and were evaluated by 2 observers. The chi-square test was used to assess the nominal variables. In strip perforations, the accuracies of low- and high-resolution modes were 75% and 83% for NewTom 3G and 67% and 69% for Cranex 3D. In root perforations, the accuracies of low- and high-resolution modes were 79% and 83% for NewTom 3G and was 56% and 73% for Cranex 3D. The accuracy of the 2 CBCT systems was different for the detection of strip and root perforations. The Cranex 3D had non-significantly higher accuracy than the NewTom 3G. In both scanners, the high-resolution mode yielded significantly higher accuracy than the low-resolution mode. The diagnostic accuracy of CBCT scans was not affected by the perforation diameter.

  8. Comparative evaluations of the results of common X-ray examinations and computerized tomography in patients with exogenous allergic alveolitis

    International Nuclear Information System (INIS)

    Khomenko, A.G.; Dmitrieva, L.I.; Khikkel', Kh.G.; Myuller, S.

    1989-01-01

    A correlative study of the results of x-ray examination using routine methods and computerized tomography (CT) was conducted to specify the roentgenomorphological substrate of changes in patients with exogenous allergic alveolitis. The established complex of routine methods is informative enough to interpret the revealed changes. However, at early stages CT helps to specify semiotics and permits obtaining additional information, particularly on quantitative, i.e. densitometric changes. In diffuse and disseminated pulmonary lesions CT can be used as an additional method

  9. X-ray exposure dose for the gonadal gland by the examination of computerized tomography and its protection

    International Nuclear Information System (INIS)

    Moriuchi, Iwao; Kaiya, Hisanori; Hirata, Toshifumi; Asada, Shuichi

    1978-01-01

    Computerized tomography (CT) is very useful for neuroradiological examination, and so it may possibly be used for screening tests. But x-ray exposure dose by a examination of CT is considerable, especially for the male gonadal gland. This study showed that the dose from a complete CT examination of 10 - 15 scans for a male gonadal gland was about 1,800 times more than a single plain neuroradiography. But by only a 0.07 mm lead equivalent protecter, the exposure dose resulting from CT for a gonadal gland could be reduced to 0.0 mrad. (auth.)

  10. Using high resolution X-ray computed tomography to create an image based model of a lymph node.

    Science.gov (United States)

    Cooper, L J; Zeller-Plumhoff, B; Clough, G F; Ganapathisubramani, B; Roose, T

    2018-07-14

    Lymph nodes are an important part of the immune system. They filter the lymphatic fluid as it is transported from the tissues before being returned to the blood stream. The fluid flow through the nodes influences the behaviour of the immune cells that gather within the nodes and the structure of the node itself. Measuring the fluid flow in lymph nodes experimentally is challenging due to their small size and fragility. In this paper, we present high resolution X-ray computed tomography images of a murine lymph node. The impact of the resulting visualized structures on fluid transport are investigated using an image based model. The high contrast between different structures within the lymph node provided by phase contrast X-ray computed tomography reconstruction results in images that, when related to the permeability of the lymph node tissue, suggest an increased fluid velocity through the interstitial channels in the lymph node tissue. Fluid taking a direct path from the afferent to the efferent lymphatic vessel, through the centre of the node, moved faster than the fluid that flowed around the periphery of the lymph node. This is a possible mechanism for particles being moved into the cortex. Copyright © 2018 Elsevier Ltd. All rights reserved.

  11. High-definition optical coherence tomography

    DEFF Research Database (Denmark)

    Boone, Marc; Norrenberg, Sarah; Jemec, Gregor

    2013-01-01

    to those described for reflectance confocal microscopy but with the advantages not only to visualize individual cells up to a depth of 570 μm but also in both slice and en face mode. An adapted algorithmic method for pattern analysis of common inflammatory skin diseases could be proposed. This new......High-definition optical coherence tomography (HD-OCT) is a non-invasive technique for morphological investigation of tissue with cellular resolution filling the imaging gap between reflectance confocal microscopy and conventional optical coherence tomography. The aim of this study is first...... dermatitis. Additional studies to test the sensitivity and specificity of the proposed algorithm for pattern analysis are essential. The other categories of Ackerman's pattern recognition need to be evaluated. This study provides a set of morphological features generated by HD-OCT imaging very similar...

  12. Aspects of pulmonary histiocytosis X on high resolution computed tomography; Aspectos da histiocitose X pulmonar na tomografia computadorizada de alta resolucao (TCAR)

    Energy Technology Data Exchange (ETDEWEB)

    Costa, N.S.S.; Castro Lessa Angela, M.T. de; Angelo Junior, J.R.L.; Silva, F.M.D.; Kavakama, J.; Carvalho, C.R.R. de; Cerri, G.G. [Sao Paulo Univ., SP (Brazil). Faculdade de Medicina. Hospital das Clinicas. Inst. do Coracao

    1995-01-01

    Pulmonary histiocytosis X is a disease that occurs in young adults and presents with nodules and cysts, mainly in upper lobes, with consequent pulmonary fibrosis. These pulmonary changes are virtually pathognomonic findings on high resolution computed tomography, that allows estimate the area of the lung involved and distinguish histiocytosis X from other disorders that also produces nodules and cysts. (author). 10 refs, 2 tabs, 6 figs.

  13. High resolution seismic tomography imaging of Ireland with quarry blast data

    Science.gov (United States)

    Arroucau, P.; Lebedev, S.; Bean, C. J.; Grannell, J.

    2017-12-01

    Local earthquake tomography is a well established tool to image geological structure at depth. That technique, however, is difficult to apply in slowly deforming regions, where local earthquakes are typically rare and of small magnitude, resulting in sparse data sampling. The natural earthquake seismicity of Ireland is very low. That due to quarry and mining blasts, on the other hand, is high and homogeneously distributed. As a consequence, and thanks to the dense and nearly uniform coverage achieved in the past ten years by temporary and permanent broadband seismological stations, the quarry blasts offer an alternative approach for high resolution seismic imaging of the crust and uppermost mantle beneath Ireland. We detected about 1,500 quarry blasts in Ireland and Northern Ireland between 2011 and 2014, for which we manually picked more than 15,000 P- and 20,000 S-wave first arrival times. The anthropogenic, explosive origin of those events was unambiguously assessed based on location, occurrence time and waveform characteristics. Here, we present a preliminary 3D tomographic model obtained from the inversion of 3,800 P-wave arrival times associated with a subset of 500 events observed in 2011, using FMTOMO tomographic code. Forward modeling is performed with the Fast Marching Method (FMM) and the inverse problem is solved iteratively using a gradient-based subspace inversion scheme after careful selection of damping and smoothing regularization parameters. The results illuminate the geological structure of Ireland from deposit to crustal scale in unprecedented detail, as demonstrated by sensitivity analysis, source relocation with the 3D velocity model and comparisons with surface geology.

  14. Automated high resolution full-field spatial coherence tomography for quantitative phase imaging of human red blood cells

    Science.gov (United States)

    Singla, Neeru; Dubey, Kavita; Srivastava, Vishal; Ahmad, Azeem; Mehta, D. S.

    2018-02-01

    We developed an automated high-resolution full-field spatial coherence tomography (FF-SCT) microscope for quantitative phase imaging that is based on the spatial, rather than the temporal, coherence gating. The Red and Green color laser light was used for finding the quantitative phase images of unstained human red blood cells (RBCs). This study uses morphological parameters of unstained RBCs phase images to distinguish between normal and infected cells. We recorded the single interferogram by a FF-SCT microscope for red and green color wavelength and average the two phase images to further reduced the noise artifacts. In order to characterize anemia infected from normal cells different morphological features were extracted and these features were used to train machine learning ensemble model to classify RBCs with high accuracy.

  15. High-resolution CT of lesions of the optic nerve

    International Nuclear Information System (INIS)

    Peyster, R.G.; Hoover, E.D.; Hershey, B.L.; Haskin, M.E.

    1983-01-01

    The optic nerves are well demonstrated by high-resolution computed tomography. Involvement of the optic nerve by optic gliomas and optic nerve sheath meningiomas is well known. However, nonneoplastic processes such as increased intracranial pressure, optic neuritis, Grave ophthalmopathy, and orbital pseudotumor may also alter the appearance of the optic nerve/sheath on computed tomography. Certain clinical and computed tomographic features permit distinction of these nonneoplastic tumefactions from tumors

  16. Quality of computerized tomography exams proposed by a quality certification program

    International Nuclear Information System (INIS)

    Carlos, Marcia Terezinha

    1999-01-01

    Brazilian College of Radiologists (CBR) is concerned about the quality of radiological practices in the country. Actions in direction of accreditation programmes and standardization of the performance in imaging modalities have been implemented. The first accreditation programme was in mammography. In Brazil, computed tomography spread all over the country. Due high radiation dose to the patient and the continuous technological development, an accreditation programme in CT practice is necessary. A pilot programme has been carried out in the area of Rio de Janeiro with the participation of 11 CT facilities with 12 CT units. The background information follows Document EUR 16262 E uropean Guidelines of Quality Criteria for Computed Tomography . Initially practice data were collected through structured interviews using a standardized questionnaire. In regard to the assessment of clinical image quality, two examinations were selected: brain general and abdomen general. Three radiologists specialized in computed tomography evaluated the image quality criteria from a sample of examinations from the participant facilities. Other aspects selected to the assessment of the overall performance are: technical parameters of the examinations; image physical parameters (noise, spatial resolution, sensitivity profile) and radiation dose. Radiation dose and image quality criteria were fulfilled by 7 of 12 brain general examinations analyzed and only 5 of 10 abdomen general examinations analyzed. At the moment, it was not possible to get a conclusion about image quality based on measurements of physical parameters. Other factors affecting overall image quality were: technical limitation of CT units and practitioners are not able to fully handle the technical parameters of the examination. Dose and image quality criteria shall be the basis of an accreditation programme in CT and Brazilian College of Radiology has to use the experience of this work to implement a programme at national

  17. Geometrical efficiency in computerized tomography: generalized model

    International Nuclear Information System (INIS)

    Costa, P.R.; Robilotta, C.C.

    1992-01-01

    A simplified model for producing sensitivity and exposure profiles in computerized tomographic system was recently developed allowing the forecast of profiles behaviour in the rotation center of the system. The generalization of this model for some point of the image plane was described, and the geometrical efficiency could be evaluated. (C.G.C.)

  18. Possible application of computerized tomography and ultrasonography in diagnosing hyperparathyroidism

    International Nuclear Information System (INIS)

    Sotornik, I.; Sobota, J.; Kocandrle, V.; Drab, K.; Klima, J.; Zastava, V.; Mrhova, O.

    1985-01-01

    Initial experience is reported with the application of computerized tomography (CT) in the diagnosis of enlarged parathyroid glands in 19 patients with chronic renal failure who developed renal osteopathy in the course of hemodialysis treatment; in one patient an adenoma of the parathyroid associated with primary hyperparathyroidism was revealed. In the group of patients CT revealed enlarged parathyroid glands 14 times including 7 patients subjected to surgery of the parathyroid where the CT finding was confirmed in all instances. In patients with CT confirmed enlargement of the parathyroid glands, significantly higher levels of the bone isoenzyme ALP (p<0.05), total ACP (p<0.01), OH-proline in the blood (p<0.01) and C-terminal PTH (p<0.01) were found along with an advanced X-ray finding of hyperparathyroidism, as compared with patients with negative CT result. CT examination is a valuable noninvasive method which, together with the mentioned biochemical and X-ray findings, contributes in a fundamental way to the decision on whether surgery of the parathyroid glands should be undertaken. It is believed that at present it is difficult to provide evidence of enlarged parathyroids by means of sonographic examinations and the method calls for further investigation. (author)

  19. High-resolution breast tomography at high energy: a feasibility study of phase contrast imaging on a whole breast

    International Nuclear Information System (INIS)

    Sztrókay, A; Schlossbauer, T; Bamberg, F; Reiser, M F; Coan, P; Diemoz, P C; Brun, E; Bravin, A; Mayr, D

    2012-01-01

    Previous studies on phase contrast imaging (PCI) mammography have demonstrated an enhancement of breast morphology and cancerous tissue visualization compared to conventional imaging. We show here the first results of the PCI analyser-based imaging (ABI) in computed tomography (CT) mode on whole and large (>12 cm) tumour-bearing breast tissues. We demonstrate in this work the capability of the technique of working at high x-ray energies and producing high-contrast images of large and complex specimens. One entire breast of an 80-year-old woman with invasive ductal cancer was imaged using ABI-CT with monochromatic 70 keV x-rays and an area detector of 92×92 µm 2 pixel size. Sagittal slices were reconstructed from the acquired data, and compared to corresponding histological sections. Comparison with conventional absorption-based CT was also performed. Five blinded radiologists quantitatively evaluated the visual aspects of the ABI-CT images with respect to sharpness, soft tissue contrast, tissue boundaries and the discrimination of different structures/tissues. ABI-CT excellently depicted the entire 3D architecture of the breast volume by providing high-resolution and high-contrast images of the normal and cancerous breast tissues. These results are an important step in the evolution of PCI-CT towards its clinical implementation. (paper)

  20. High-resolution breast tomography at high energy: a feasibility study of phase contrast imaging on a whole breast

    Science.gov (United States)

    Sztrókay, A.; Diemoz, P. C.; Schlossbauer, T.; Brun, E.; Bamberg, F.; Mayr, D.; Reiser, M. F.; Bravin, A.; Coan, P.

    2012-05-01

    Previous studies on phase contrast imaging (PCI) mammography have demonstrated an enhancement of breast morphology and cancerous tissue visualization compared to conventional imaging. We show here the first results of the PCI analyser-based imaging (ABI) in computed tomography (CT) mode on whole and large (>12 cm) tumour-bearing breast tissues. We demonstrate in this work the capability of the technique of working at high x-ray energies and producing high-contrast images of large and complex specimens. One entire breast of an 80-year-old woman with invasive ductal cancer was imaged using ABI-CT with monochromatic 70 keV x-rays and an area detector of 92×92 µm2 pixel size. Sagittal slices were reconstructed from the acquired data, and compared to corresponding histological sections. Comparison with conventional absorption-based CT was also performed. Five blinded radiologists quantitatively evaluated the visual aspects of the ABI-CT images with respect to sharpness, soft tissue contrast, tissue boundaries and the discrimination of different structures/tissues. ABI-CT excellently depicted the entire 3D architecture of the breast volume by providing high-resolution and high-contrast images of the normal and cancerous breast tissues. These results are an important step in the evolution of PCI-CT towards its clinical implementation.

  1. Development of a lab-scale, high-resolution, tube-generated X-ray computed-tomography system for three-dimensional (3D) materials characterization

    International Nuclear Information System (INIS)

    Mertens, J.C.E.; Williams, J.J.; Chawla, Nikhilesh

    2014-01-01

    The design and construction of a modular high resolution X-ray computed tomography (XCT) system is highlighted in this paper. The design approach is detailed for meeting a specified set of instrument performance goals tailored towards experimental versatility and high resolution imaging. The XCT tool is unique in the detector and X-ray source design configuration, enabling control in the balance between detection efficiency and spatial resolution. The system package is also unique: The sample manipulation approach implemented enables a wide gamut of in situ experimentation to analyze structure evolution under applied stimulus, by optimizing scan conditions through a high degree of controllability. The component selection and design process is detailed: Incorporated components are specified, custom designs are shared, and the approach for their integration into a fully functional XCT scanner is provided. Custom designs discussed include the dual-target X-ray source cradle which maintains position and trajectory of the beam between the two X-ray target configurations with respect to a scintillator mounting and positioning assembly and the imaging sensor, as well as a novel large-format X-ray detector with enhanced adaptability. The instrument is discussed from an operational point of view, including the details of data acquisition and processing implemented for 3D imaging via micro-CT. The performance of the instrument is demonstrated on a silica-glass particle/hydroxyl-terminated-polybutadiene (HTPB) matrix binder PBX simulant. Post-scan data processing, specifically segmentation of the sample's relevant microstructure from the 3D reconstruction, is provided to demonstrate the utility of the instrument. - Highlights: • Custom built X-ray tomography system for microstructural characterization • Detector design for maximizing polychromatic X-ray detection efficiency • X-ray design offered for maximizing X-ray flux with respect to imaging resolution

  2. Correlations between computerized tomography of the head and motor developmental disturbances of children with cerebral palsy

    International Nuclear Information System (INIS)

    Chen, Yu-Herng

    1981-01-01

    Two hundred and eighty-two children with cerebral palsy (C.P.) and thirty-seven normal children were studied by computerized tomography (C.T.) of the head for finding out the correlations between the organic damage of the brain and the motor developmental disturbance. The abnormal findings of C.T. were: enlargement of the ventricular system, high density area, low density area and porencephalus, enlargement of the sulcus and anomaly of the medial structure. Enlargement of the ventricular system seemed to have correlation with spasticity; the portion and the extent of the enlargement corresponded to the affected extremities and the severity of the spasticity. Children of other types also showed various abnormal C.T. findings but, in general, less than that of spastic types. The prognosis of the motor development of C.P. children cannot be predicted by serial C.T. examinations strictly, because early treatment could cause improvement to that of these children. However, it is of worthy notice that C.T. is an effective method of helping to diagnose the motor developmental disturbance in earlier childhood. (author)

  3. Computerized tomographic in non-destructive testing

    International Nuclear Information System (INIS)

    Lopes, R.T.

    1988-01-01

    The process of computerized tomography has been developed for medical imaging purposes using tomographs with X-ray, and little attention has been given to others possibles applications of technique, because of its cost. As an alternative for the problem, we constructed a Tomographic System (STAC-1), using gamma-rays, for nonmedical applications. In this work we summarize the basic theory of reconstructing images using computerized tomography and we describe the considerations leading to the development of the experimental system. The method of reconstruction image implanted in the system is the filtered backprojection or convolution, with a digital filters system to carried on a pre-filtering in the projections. The experimental system is described, with details of control and the data processing. An alternative and a complementary system, using film as a detector is shown in preliminary form . This thesis discuss and shows the theorical and practical aspects, considered in the construction of the STAC-1, and also its limitations and apllications [pt

  4. Imagenological characterization by Computerized Axial Tomography of the primary intracranial tumors

    International Nuclear Information System (INIS)

    Sosa Rivera, Manuel; Quintas Santana, Maria

    2009-01-01

    A descriptive observational study to 56 patients with imagenological diagnosis of primary intracranial neoplasia attended in the service of imagenology of the Provincial Docent Hospital 'Dr. Antonio Luaces Iraola' was carried out from March 1st 2006 to February 1st 2008, with the aim of characterizing these injuries by Computerized Axial Tomography and establishing an evaluation with the histological diagnosis. A questionnaire with the following variables was applied: sex, presuntive age, clinic, topographical characteristics (location, size, tumoral density, changes with administration of the resistance, calcifications, effect of mass and evaluation of the imagenological diagnosis with the histological diagnosis. Masculine sex and the group of ages of 60 are more predominated. The more frequent clinical manifestations were migraine, convulsions, difficulty to walk and vertigo. The size of the injury that prevailed was of 5, 9 and 2, 1 cm with supratentorial location. The majority of primary intracranial neoplasms were hypodense, and enhancement of the injuries with the administration of the resistance was observed. The mass effect bears a close relation with the location and size of the injury. The imagenological diagnosis fitted in with the histological one, being the gliomas the more frequent histological type

  5. Ultra-low noise supercontinuum source for ultra-high resolution optical coherence tomography at 1300 nm

    Science.gov (United States)

    Gonzalo, I. B.; Maria, M.; Engelsholm, R. D.; Feuchter, T.; Leick, L.; Moselund, P. M.; Podoleanu, A.; Bang, O.

    2018-02-01

    Supercontinuum (SC) sources are of great interest for many applications due to their ultra-broad optical bandwidth, good beam quality and high power spectral density [1]. In particular, the high average power over large bandwidths makes SC light sources excellent candidates for ultra-high resolution optical coherence tomography (UHR-OCT) [2-5]. However, conventional SC sources suffer from high pulse-to-pulse intensity fluctuations as a result of the noise-sensitive nonlinear effects involved in the SC generation process [6-9]. This intensity noise from the SC source can limit the performance of OCT, resulting in a reduced signal-to-noise ratio (SNR) [10-12]. Much work has been done to reduce the noise of the SC sources for instance with fiber tapers [7,8] or increasing the repetition rate of the pump laser for averaging in the spectrometer [10,12]. An alternative approach is to use all-normal dispersion (ANDi) fibers [13,14] to generate SC light from well-known coherent nonlinear processes [15-17]. In fact, reduction of SC noise using ANDi fibers compared to anomalous dispersion SC pumped by sub-picosecond pulses has been recently demonstrated [18], but a cladding mode was used to stabilize the ANDi SC. In this work, we characterize the noise performance of a femtosecond pumped ANDi based SC and a commercial SC source in an UHR-OCT system at 1300 nm. We show that the ANDi based SC presents exceptional noise properties compared to a commercial source. An improvement of 5 dB in SNR is measured in the UHR-OCT system, and the noise behavior resembles that of a superluminiscent diode. This preliminary study is a step forward towards development of an ultra-low noise SC source at 1300 nm for ultra-high resolution OCT.

  6. Computerized tomography with X-rays: an instrument in the analysis physico-chemical between formations and drilling fluids interactions; Tomografia computadorizada com raios-X: uma ferramenta na analise das interacoes fisico-quimicas entre as formacoes rochosas e fluidos de perfuracao

    Energy Technology Data Exchange (ETDEWEB)

    Coelho, Marcus Vinicius Cavalcante

    1999-12-31

    In this study it is demonstrated the applicability of the Computerized Tomography technique with x-rays to evaluate the reactivity degree between various drilling fluids and argillaceous sediments (Shales and Sandstones). The research has been conducted in the Rock-Fluid Interaction Pressure Simulator (RFIPS), where the possible physico-chemical alterations can be observed through successive tomography images, which are obtained during the flow of the fluid through the samples. In addition, it was noticed the formation of mud cake in Berea Sandstones samples in the RFIPS, though the Computerized Tomography with X-rays, when utilizing drilling fluids weighted with the baryte. (author) 35 refs., 38 figs., 5 tabs.

  7. Computerized tomography with X-rays: an instrument in the analysis physico-chemical between formations and drilling fluids interactions; Tomografia computadorizada com raios-X: uma ferramenta na analise das interacoes fisico-quimicas entre as formacoes rochosas e fluidos de perfuracao

    Energy Technology Data Exchange (ETDEWEB)

    Coelho, Marcus Vinicius Cavalcante

    1998-12-31

    In this study it is demonstrated the applicability of the Computerized Tomography technique with x-rays to evaluate the reactivity degree between various drilling fluids and argillaceous sediments (Shales and Sandstones). The research has been conducted in the Rock-Fluid Interaction Pressure Simulator (RFIPS), where the possible physico-chemical alterations can be observed through successive tomography images, which are obtained during the flow of the fluid through the samples. In addition, it was noticed the formation of mud cake in Berea Sandstones samples in the RFIPS, though the Computerized Tomography with X-rays, when utilizing drilling fluids weighted with the baryte. (author) 35 refs., 38 figs., 5 tabs.

  8. Calculating the number of shock waves, expulsion time, and optimum stone parameters based on noncontrast computerized tomography characteristics.

    Science.gov (United States)

    Foda, Khaled; Abdeldaeim, Hussein; Youssif, Mohamed; Assem, Akram

    2013-11-01

    To define the parameters that accompanied a successful extracorporeal shock wave lithotripsy (ESWL), namely the number of shock waves (SWs), expulsion time (ET), mean stone density (MSD), and the skin-to-stone distance (SSD). A total of 368 patients diagnosed with renal calculi using noncontrast computerized tomography had their MSD, diameter, and SSD recorded. All patients were treated using a Siemens lithotripter. ESWL success meant a stone-free status or presence of residual fragments 934 HUs and SSD >99 mm. The required number of SWs and the expected ET can be anticipated. Copyright © 2013 Elsevier Inc. All rights reserved.

  9. Using three-dimensional-computerized tomography as a diagnostic tool for temporo-mandibular joint ankylosis: a case report.

    Science.gov (United States)

    Kao, S Y; Chou, J; Lo, J; Yang, J; Chou, A P; Joe, C J; Chang, R C

    1999-04-01

    Roentgenographic examination has long been a useful diagnostic tool for temporo-mandibular joint (TMJ) disease. The methods include TMJ tomography, panoramic radiography and computerized tomography (CT) scan with or without injection of contrast media. Recently, three-dimensional CT (3D-CT), reconstructed from the two-dimensional image of a CT scan to simulate the soft tissue or bony structure of the real target, was proposed. In this report, a case of TMJ ankylosis due to traumatic injury is presented. 3D-CT was employed as one of the presurgical roentgenographic diagnostic tools. The conventional radiographic examination including panoramic radiography and tomography showed lesions in both sides of the mandible. CT scanning further suggested that the right-sided lesion was more severe than that on the left. With 3D-CT image reconstruction the size and extent of the lesions were clearly observable. The decision was made to proceed with an initial surgical approach on the right side. With condylectomy and condylar replacement using an autogenous costochondral graft on the right side, the range of mouth opening improved significantly. In this case report, 3D-CT demonstrates its advantages as a tool for the correct and precise diagnosis of TMJ ankylosis.

  10. Image reconstruction in computerized tomography using the convolution method

    International Nuclear Information System (INIS)

    Oliveira Rebelo, A.M. de.

    1984-03-01

    In the present work an algoritin was derived, using the analytical convolution method (filtered back-projection) for two-dimensional or three-dimensional image reconstruction in computerized tomography applied to non-destructive testing and to the medical use. This mathematical model is based on the analytical Fourier transform method for image reconstruction. This model consists of a discontinuous system formed by an NxN array of cells (pixels). The attenuation in the object under study of a colimated gamma ray beam has been determined for various positions and incidence angles (projections) in terms of the interaction of the beam with the intercepted pixels. The contribution of each pixel to beam attenuation was determined using the weight function W ij which was used for simulated tests. Simulated tests using standard objects with attenuation coefficients in the range of 0,2 to 0,7 cm -1 were carried out using cell arrays of up to 25x25. One application was carried out in the medical area simulating image reconstruction of an arm phantom with attenuation coefficients in the range of 0,2 to 0,5 cm -1 using cell arrays of 41x41. The simulated results show that, in objects with a great number of interfaces and great variations of attenuation coefficients at these interfaces, a good reconstruction is obtained with the number of projections equal to the reconstruction matrix dimension. A good reconstruction is otherwise obtained with fewer projections. (author) [pt

  11. Value of intravenous injection of contrast media for computerized tomography of the thorax

    International Nuclear Information System (INIS)

    Beyer-Enke, S.A.; Goerich, J.; Mueller, M.; Kaick, G. van; Tuengerthal, S.

    1988-01-01

    107 patients with thoracal or mediastinal growths underwent computerized tomography of the thorax both in normal condition and after receiving intravenous applications of non-ionic X-ray contrast media. The additional information obtained by use of contrast media was established in relation to the histological findings. The method led to enhanced demarcation of the tumor of the mediastinum or hilus in 40% of the patients. Tumor perfusion was helpful in 20% of the cases for differential diagnosis. Vessel infiltrations or abnormal conditions were found in about 30% of patients. 24% of the tests yielded no additional information. Analysing CT as compared to the histological examination of lymph nodes proved CT under normal conditions to be a sensitive method in 29% of cases if the hilus was the site of the tumor; contrast media raised this sensitivity to 43%. In the mediastinal area, sensitivity was 44% without and 56% with contrast media. (orig.) [de

  12. Quantitative computerized tomography for staging and follow up of patients with prostatic cancer

    International Nuclear Information System (INIS)

    Golimbu, C.; Golimbu, M.; Firooznia, H.; Rafii, M.; Morales, P.

    1987-01-01

    Prostate carcinoma has propensity to metastasize to skeleton, most frequently affecting the lumbar spine. The isotope bone scan and serum prostatic acid phosphatase (PAP) have been considered most reliable in documenting cancer spread. However, the former has been shown to have low specificity, and the latter was found to be increased in patients with localized disease or normal in patients with proven metastases. In a previous study of a group of patients at risk of having metastatic bone involvement, albeit not revealed by standard methods, the authors demonstrated the ability of quantitative computerized tomography (QCT) to depict early stages of bone metastases (Golimbu et. al., 1986). They also demonstrated its usefulness in assessing the response to treatment. The authors extended their study to further evaluate the accuracy of QCT in comparison with Tc99m bone scan and serum PAP for early detection of bone metastases and for quantitation of metastatic bone lesions response to therapy

  13. High-resolution computed tomography findings in elderly patients with asthma

    International Nuclear Information System (INIS)

    Yilmaz, Sevda; Ekici, Aydanur; Ekici, Mehmet; Keles, Hatice

    2006-01-01

    Objective: Based on the hypothesis that airway remodelling is related to the duration of asthma, HRCT scanning should show greater abnormalities in the early-onset than the late-onset asthmatics. It was, therefore, intended to assess the presence and the frequency of airway and parenchymal abnormalities with high-resolution computed tomography (HRCT) in elderly asthmatic patients, and to determine whether these abnormalities are related to the duration of asthma. Patients and methods: Sixty-eight clinically stable asthmatic patients aged ≥60 yr were included in this prospective study. The patients were separated into two groups according to the duration of symptoms as late-onset asthma (n = 31) with disease duration of <5 yr, and early-onset asthma (n = 37) with disease duration of ≥5 yr. All patients were lifelong non-smoker and had been using inhaled beta agonists and inhaled steroids. HRCT-scanning and histamine inhalation test were performed on all patients. Results: In comparison with late-onset asthmatic patients, those with early-onset asthma had significantly higher frequency of emphysema (21.6% versus 0.0%, p = 0.006), bronchial dilatation (13.9% versus 0.0%, p 0.03) and bronchial wall thickness (41.7% versus 12.9%, p = 0.01). Multiple logistic regression analysis identified that early-onset of disease was an independent risk factor for the presence of irreversible HRCT-scan abnormalities in elderly asthmatics [odds ratio (OR): 9.4 (2.7-32.7), p 0.00001]. Conclusion: Present data suggest that HRCT abnormalities in early-onset elderly asthmatics reflect parenchymal and airway changes that become irreversible throughout the long course of the disease

  14. Hygromorphic characterization of softwood under high resolution X-ray tomography for hygrothermal simulation

    Science.gov (United States)

    El Hachem, Chady; Abahri, Kamilia; Vicente, Jérôme; Bennacer, Rachid; Belarbi, Rafik

    2018-03-01

    Because of their complex hygromorphic shape, microstructural study of wooden materials behavior has recently been the point of interest of researchers. The purpose of this study, in a first part, consists in characterizing by high resolution X-ray tomography the microstructural properties of spruce wood. In a second part, the subresulting geometrical parameters will be incorporated when evaluating the wooden hygrothermal transfers behavior. To do so, volume reconstructions of 3 Dimensional images (3D), obtained with a voxel size of 0.5 μm were achieved. The post-treatment of the corresponding volumes has given access to averages and standard deviations of lumens' diameters and cell walls' thicknesses. These results were performed for both early wood and latewood. Further, a segmentation approach for individualizing wood lumens was developed, which presents an important challenge in understanding localized physical properties. In this context, 3D heat and mass transfers within the real reconstructed geometries took place in order to highlight the effect of wood directions on the equivalent conductivity and moisture diffusion coefficients. Results confirm that the softwood cellular structure has a critical impact on the reliability of the studied physical parameters.

  15. A study of root canal morphology of human primary incisors and molars using cone beam computerized tomography: An in vitro study

    OpenAIRE

    Vivek Gaurav; Nikhil Srivastava; Vivek Rana; Vivek Kumar Adlakha

    2013-01-01

    Background: Variations in morphology of root canals in primary teeth usually leads to complications during and after endodontic therapy. To improve the success in endodontics, a thorough knowledge of the root canal morphology is essential. Aim: The aim of this study was to assess the variation in number and morphology of the root canals of primary incisors and molars and to study the applicability of cone beam computerized tomography (CBCT) in assessing the same. Settings and Design: A total ...

  16. AUTOMATIC ESTIMATION OF SIZE PARAMETERS USING VERIFIED COMPUTERIZED STEREOANALYSIS

    Directory of Open Access Journals (Sweden)

    Peter R Mouton

    2011-05-01

    Full Text Available State-of-the-art computerized stereology systems combine high-resolution video microscopy and hardwaresoftware integration with stereological methods to assist users in quantifying multidimensional parameters of importance to biomedical research, including volume, surface area, length, number, their variation and spatial distribution. The requirement for constant interactions between a trained, non-expert user and the targeted features of interest currently limits the throughput efficiency of these systems. To address this issue we developed a novel approach for automatic stereological analysis of 2-D images, Verified Computerized Stereoanalysis (VCS. The VCS approach minimizes the need for user interactions with high contrast [high signal-to-noise ratio (S:N] biological objects of interest. Performance testing of the VCS approach confirmed dramatic increases in the efficiency of total object volume (size estimation, without a loss of accuracy or precision compared to conventional computerized stereology. The broad application of high efficiency VCS to high-contrast biological objects on tissue sections could reduce labor costs, enhance hypothesis testing, and accelerate the progress of biomedical research focused on improvements in health and the management of disease.

  17. Muscle area and muscle density of osteoarthritis of the knee joint studied by computerized tomography

    International Nuclear Information System (INIS)

    Suzuki, Nobuharu; Onosawa, Toshihiro; Shibata, Minoru; Yamashita, Izumi; Yoshimura, Shinichiro; Muraoka, Shunichi; Asano, Akira

    1985-01-01

    In order to investigate the etiology and pathology of osteoarthritis of the knee joints (OA), the areas and density of the muscle 10 cm above the knee were compared using computerized tomography (CT) in 26 knees from 19 normal persons, 30 knees from 17 patients with OA, and 14 knees from 7 patients with rheumatoid arthritis. The areas of the quadriceps musculi of thigh were remarkably decreased and the areas of the flexor musculi were comparatively maintained in the patients with OA. Muscle density was markedly lowered in the musculi semimembranosus and biceps femoris long head. Fatty tissues were seen in the whole area of the venter on CT in some of the patients with OA. These findings are considered to be of major importance when studying the etiology of OA. (Namekawa, K.)

  18. Application of cadmium telluride detectors to high energy computed tomography

    International Nuclear Information System (INIS)

    Glasser, F.; Thomas, G.; Cuzin, M.; Verger, L.

    1991-01-01

    15 years ago, Cadmium Telluride detectors have been investigated in our laboratory as possible detectors for medical scanners [1]. Today most of these machines are using high pressure Xenon gas as multicells detectors, BGO or CdWO 4 scintillators for industrial computerized tomography. Xenon gas detectors are well suited for detection of 100 KeV X-rays and enables to build 1000 cells homogeneous detector with a dynamic range of 3 decades. BGO and CdWO 4 scintillators, associated with photomultipliers or photodiodes are used for higher energy (400 KeV). They present a low afterglow and a dynamic range of 4 to 5 decades. Non destructive testing of very absorbing objects (eg 2 m diameter solid rocket motor) by X-ray tomography requires much higher energy X-rays (16 MeV) and doses up to 12000 rads/min at 1 meter. For this application Cadmium Telluride detectors operating as photoconductors are well suited. A prototype of tomograph machine, able to scan 0.5 m diameter high density objects has been realized with 25 CdTe detectors (25x15x0.8 mm 3 ). It produces good quality 1024x1024 tomographic images

  19. Pulmonary leukemic involvement: high-resolution computed tomography evaluation; Comprometimento pulmonar nas leucemias: avaliacao por tomografia computadorizada de alta resolucao

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Ana Paola de [Universidade Federal, Rio de Janeiro, RJ (Brazil). Faculdade de Medicina. Programa de Pos-graduacao em Radiologia; Marchiori, Edson [Universidade Federal Fluminense, Niteroi, RJ (Brazil). Dept. de Radiologia; Souza, Junior, Arthur Soares [Faculdade de Medicina de Sao Jose do Rio Preto (FAMERP), SP (Brazil). Dept. de Radiologia

    2004-12-01

    Objective: To evaluate the role of high-resolution computed tomography (HRCT) in patients with leukemia and pulmonary symptoms, to establish the main patterns and to correlate them with the etiology. Materials and Methods: This is a retrospective study of the HRCT of 15 patients with leukemia and pulmonary symptoms. The examinations were performed using a spatial high-resolution protocol and were analyzed by two independent radiologists. Results: The main HRCT patterns found were ground-glass opacity (n=11), consolidation (n=9), airspace nodules (n=3), septal thickening (n=3), tree-in-bud pattern (n=3), and pleural effusion (n=3). Pulmonary infection was the most common finding seen in 12 patients: bacterial pneumonia (n=6), fungal infection (n = 4), pulmonary tuberculosis (n=1) and viral infection (n=1). Leukemic pleural infiltration (n=1), lymphoma (n=1) and pulmonary hemorrhage (n=1) were detected in the other three patients. Conclusion: HRCT is an important tool that may suggest the cause of lung involvement, its extension and in some cases to guide invasive procedures in patients with leukemia. (author)

  20. Potentials of high resolution magnetic resonance imaging versus computed tomography for preoperative local staging of colon cancer

    International Nuclear Information System (INIS)

    Rollven, Erik; Blomqvist, Lennart; Holm, Torbjorn; Glimelius, Bengt; Loerinc, Esther

    2013-01-01

    Background: Preoperative identification of locally advanced colon cancer is of importance in order to properly plan treatment. Purpose: To study high resolution T2-weighted magnetic resonance imaging (MRI) versus computed tomography (CT) for preoperative staging of colon cancer with surgery and histopathology as reference standard. Material and Methods: Twenty-eight patients with a total of 29 tumors were included. Patients were examined on a 1.5 T MR unit using a phased array body coil. T2 turbo spin-echo high resolution sequences were obtained in a coronal, transverse, and perpendicular plane to the long axis of the colon at the site of the tumor. Contrast-enhanced CT was performed using a protocol for metastasis staging. The examinations were independently evaluated by two gastrointestinal radiologists using criteria adapted to imaging for prediction of T-stage, N-stage, and extramural venous invasion. Based on the T-stage, tumors were divided in to locally advanced (T3cd-T4) and not locally advanced (T1-T3ab). Surgical and histopathological findings served as reference standard. Results: Using MRI, T-stage, N-stage, and extramural venous invasion were correctly predicted for each observer in 90% and 93%, 72% and 69%, and 82% and 78% of cases, respectively. With CT the corresponding results were 79% and 76%, 72% and 72%, 78% and 67%. For MRI inter-observer agreements (Kappa statistics) were 0.79, 0.10, and 0.76. For CT the corresponding results were 0.64, 0.66, and 0.22. Conclusion: Patients with locally advanced colon cancer, defined as tumor stage T3cd-T4, can be identified by both high resolution MRI and CT, even when CT is performed with a metastasis staging protocol. MRI may have an advantage, due to its high soft tissue discrimination, to identify certain prognostic factors such as T-stage and extramural venous invasion

  1. Potentials of high resolution magnetic resonance imaging versus computed tomography for preoperative local staging of colon cancer

    Energy Technology Data Exchange (ETDEWEB)

    Rollven, Erik; Blomqvist, Lennart [Dept. of Diagnostic Radiology, Karolinska Univ. Hospital Solna, Stockholm (Sweden); Dept. of Molecular Medicine and Surgery, Karolinska Inst., Stockholm (Sweden)], e-mail: erik.rollven@ki.se; Holm, Torbjorn [Dept. of Molecular Medicine and Surgery, Karolinska Inst., Stockholm (Sweden); Dept. of Surgery, Karolinska Univ. Hospital Solna, Stockholm (Sweden); Glimelius, Bengt [Dept. of Radiology, Oncology and Radiation Science, Uppsala Univ., Uppsala (Sweden); Dept. of Oncology and Pathology, Karolinska Inst., Stockholm (Sweden); Loerinc, Esther [Dept. of Oncology and Pathology, Karolinska Inst., Stockholm (Sweden); Dept. of Pathology, Karolinska Univ. Hospital, Solna, Sweden (Sweden)

    2013-09-15

    Background: Preoperative identification of locally advanced colon cancer is of importance in order to properly plan treatment. Purpose: To study high resolution T2-weighted magnetic resonance imaging (MRI) versus computed tomography (CT) for preoperative staging of colon cancer with surgery and histopathology as reference standard. Material and Methods: Twenty-eight patients with a total of 29 tumors were included. Patients were examined on a 1.5 T MR unit using a phased array body coil. T2 turbo spin-echo high resolution sequences were obtained in a coronal, transverse, and perpendicular plane to the long axis of the colon at the site of the tumor. Contrast-enhanced CT was performed using a protocol for metastasis staging. The examinations were independently evaluated by two gastrointestinal radiologists using criteria adapted to imaging for prediction of T-stage, N-stage, and extramural venous invasion. Based on the T-stage, tumors were divided in to locally advanced (T3cd-T4) and not locally advanced (T1-T3ab). Surgical and histopathological findings served as reference standard. Results: Using MRI, T-stage, N-stage, and extramural venous invasion were correctly predicted for each observer in 90% and 93%, 72% and 69%, and 82% and 78% of cases, respectively. With CT the corresponding results were 79% and 76%, 72% and 72%, 78% and 67%. For MRI inter-observer agreements (Kappa statistics) were 0.79, 0.10, and 0.76. For CT the corresponding results were 0.64, 0.66, and 0.22. Conclusion: Patients with locally advanced colon cancer, defined as tumor stage T3cd-T4, can be identified by both high resolution MRI and CT, even when CT is performed with a metastasis staging protocol. MRI may have an advantage, due to its high soft tissue discrimination, to identify certain prognostic factors such as T-stage and extramural venous invasion.

  2. Quantitative assessment of liquid Ga penetration into an aluminium alloy by high-resolution X-ray tomography

    International Nuclear Information System (INIS)

    Ohgaki, T.; Toda, H.; Sinclair, I.; Buffiere, J.-Y.; Ludwig, W.; Kobayashi, T.; Niinomi, M.; Akahori, T.

    2005-01-01

    We have evaluated the liquid Ga penetration into an aluminium alloy by high-resolution X-ray tomography. The 3D visualization of a crack together with its surrounding grain structure was performed with the help of the Ga penetration technique. It is found that the advance directions of the crack-tip were strongly influenced by the grain microstructure and the branching of the crack is affected by grain distribution. In this study, the liquid Ga not only acts as a contrast agent for grain boundaries, but also expands the volume of the Al alloy due to Ga diffusion and associated processes. The 3D strain between the grains has been determined by microstructural gauging technique, which uses micropores as marker points. The 3D expansion of the sample volume, the volume reduction of micropores and the brittle fracture were evidently observed

  3. Esclerose sistêmica progressiva: aspectos na tomografia computadorizada de alta resolução Progressive systemic sclerosis: high-resolution computed tomography findings

    Directory of Open Access Journals (Sweden)

    Emerson L. Gasparetto

    2005-09-01

    Full Text Available OBJETIVO: Descrever os achados de tomografia computadorizada de alta resolução de pacientes com esclerose sistêmica pulmonar, independentemente dos sintomas respiratórios. MATERIAIS E MÉTODOS: Foram revisados 73 exames de tomografia computadorizada de alta resolução de 44 pacientes com diagnóstico de esclerodermia estabelecido através de critérios clínicos e laboratoriais. Os exames foram revisados por dois radiologistas, que estabeleceram os achados por consenso. RESULTADOS: Em 91,8% (n = 67 dos exames observaram-se alterações. Os principais achados foram lesões de padrão reticular (90,4%, opacidades em vidro-fosco (63%, bronquiectasias e bronquiolectasias de tração (56,2%, dilatação esofagiana (46,6%, faveolamento (28,8% e sinais de hipertensão pulmonar (15,6%. Na maioria dos casos as lesões eram bilaterais (89% e simétricas (58,5%. Quanto à localização, houve predomínio de lesões basais (91,2% e periféricas (92,2%. CONCLUSÃO: A esclerose sistêmica progressiva acarreta fibrose pulmonar na maioria dos pacientes, caracterizada principalmente por lesão reticular basal e periférica.OBJECTIVE: To describe the high-resolution computed tomography findings in the lung of patients with systemic sclerosis, independently of the respiratory symptoms. MATERIALS AND METHODS: Seventy-three high-resolution computed tomography scans of 44 patients with clinical diagnosis of systemic sclerosis were reviewed and defined by the consensus of two radiologists. RESULTS: Abnormalities were seen in 91.8% (n = 67 of the scans. The most frequent findings were reticular pattern (90.4%, ground-glass opacities (63%, traction bronchiectasis and bronchiolectasis (56.2%, esophageal dilatation (46.6%, honeycombing pattern (28.8% and signs of pulmonary hypertension (15.6%. In most cases the lesions were bilateral (89% and symmetrical (58.5%. The lesions were predominantly located in the basal (91.2% and peripheral (92.2% regions. CONCLUSION: In

  4. MSCT versus CBCT: evaluation of high-resolution acquisition modes for dento-maxillary and skull-base imaging

    Energy Technology Data Exchange (ETDEWEB)

    Dillenseger, Jean-Philippe; Goetz, Christian [Hopitaux Universitaires de Strasbourg, Imagerie Preclinique-UF6237, Pole d' imagerie, Strasbourg (France); Universite de Strasbourg, Icube, equipe MMB, CNRS, Strasbourg (France); Universite de Strasbourg, Federation de Medecine Translationnelle de Strasbourg, Faculte de Medecine, Strasbourg (France); Matern, Jean-Francois [Hopitaux Universitaires de Strasbourg, Imagerie Preclinique-UF6237, Pole d' imagerie, Strasbourg (France); Universite de Strasbourg, Federation de Medecine Translationnelle de Strasbourg, Faculte de Medecine, Strasbourg (France); Gros, Catherine-Isabelle; Bornert, Fabien [Universite de Strasbourg, Federation de Medecine Translationnelle de Strasbourg, Faculte de Medecine, Strasbourg (France); Universite de Strasbourg, Faculte de Chirurgie Dentaire, Strasbourg (France); Le Minor, Jean-Marie [Universite de Strasbourg, Icube, equipe MMB, CNRS, Strasbourg (France); Universite de Strasbourg, Federation de Medecine Translationnelle de Strasbourg, Faculte de Medecine, Strasbourg (France); Universite de Strasbourg, Institut d' Anatomie Normale, Strasbourg (France); Constantinesco, Andre [Hopitaux Universitaires de Strasbourg, Imagerie Preclinique-UF6237, Pole d' imagerie, Strasbourg (France); Choquet, Philippe [Hopitaux Universitaires de Strasbourg, Imagerie Preclinique-UF6237, Pole d' imagerie, Strasbourg (France); Universite de Strasbourg, Icube, equipe MMB, CNRS, Strasbourg (France); Universite de Strasbourg, Federation de Medecine Translationnelle de Strasbourg, Faculte de Medecine, Strasbourg (France); Hopital de Hautepierre, Imagerie Preclinique, Biophysique et Medecine Nucleaire, Strasbourg Cedex (France)

    2014-09-24

    Our aim was to conduct a quantitative and qualitative evaluation of high-resolution skull-bone imaging for dentistry and otolaryngology using different architectures of recent X-ray computed tomography systems. Three multi-slice computed tomography (MSCT) systems and one Cone-beam computed tomography (CBCT) system were used in this study. All apparatuses were tested with installed acquisition modes and proprietary reconstruction software enabling high-resolution bone imaging. Quantitative analyses were performed with small fields of view with the preclinical vmCT phantom, which permits to measure spatial resolution, geometrical accuracy, linearity and homogeneity. Ten operators performed visual qualitative analyses on the vmCT phantom images, and on dry human skull images. Quantitative analysis showed no significant differences between protocols in terms of linearity and geometric accuracy. All MSCT systems present a better homogeneity than the CBCT. Both quantitative and visual analyses demonstrate that CBCT acquisitions are not better than the collimated helical MSCT mode. Our results demonstrate that current high-resolution MSCT protocols could exceed the performance of a previous generation CBCT system for spatial resolution and image homogeneity. (orig.)

  5. MSCT versus CBCT: evaluation of high-resolution acquisition modes for dento-maxillary and skull-base imaging

    International Nuclear Information System (INIS)

    Dillenseger, Jean-Philippe; Goetz, Christian; Matern, Jean-Francois; Gros, Catherine-Isabelle; Bornert, Fabien; Le Minor, Jean-Marie; Constantinesco, Andre; Choquet, Philippe

    2015-01-01

    Our aim was to conduct a quantitative and qualitative evaluation of high-resolution skull-bone imaging for dentistry and otolaryngology using different architectures of recent X-ray computed tomography systems. Three multi-slice computed tomography (MSCT) systems and one Cone-beam computed tomography (CBCT) system were used in this study. All apparatuses were tested with installed acquisition modes and proprietary reconstruction software enabling high-resolution bone imaging. Quantitative analyses were performed with small fields of view with the preclinical vmCT phantom, which permits to measure spatial resolution, geometrical accuracy, linearity and homogeneity. Ten operators performed visual qualitative analyses on the vmCT phantom images, and on dry human skull images. Quantitative analysis showed no significant differences between protocols in terms of linearity and geometric accuracy. All MSCT systems present a better homogeneity than the CBCT. Both quantitative and visual analyses demonstrate that CBCT acquisitions are not better than the collimated helical MSCT mode. Our results demonstrate that current high-resolution MSCT protocols could exceed the performance of a previous generation CBCT system for spatial resolution and image homogeneity. (orig.)

  6. Ultra-high resolution C-Arm CT arthrography of the wrist: Radiation dose and image quality compared to conventional multidetector computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    Werncke, Thomas, E-mail: Werncke.Thomas@mh-hannover.de [Institute of Diagnostic and Interventional Radiology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover (Germany); Sonnow, Lena; Meyer, Bernhard C. [Institute of Diagnostic and Interventional Radiology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover (Germany); Lüpke, Matthias [University of Veterinary Medicine Hannover, Institute for General Radiology and Medical Physics, Bischofsholer Damm 15, 30173 Hannover (Germany); Hinrichs, Jan; Wacker, Frank K.; Falck, Christian von [Institute of Diagnostic and Interventional Radiology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover (Germany)

    2017-04-15

    Objective: Objective of this phantom and cadaveric study was to compare the effective radiation dose (ED) and image quality (IQ) between C-arm computed tomography (CACT) using an ultra-high resolution 1 × 1 binning with a standard 16-slice CT (MDCT) arthrography of the wrist. Methods: ED was determined with thermoluminescence dosimetry using an anthropomorphic phantom and different patient positions. Imaging was conducted in 10 human cadaveric wrists after tri-compartmental injection of diluted iodinated contrast material and a wire phantom. IQ of MDCT was compared with CACT reconstructed with a soft (CACT1) and sharp (CACT2) kernel. High and low contrast resolution was determined. Three radiologists assessed IQ of wrist structures and occurrence of image artifacts using a 5-point Likert scale. Results: ED of MDCT was comparable to standard CACT (4.3 μSv/3.7 μSv). High contrast resolution was best for CACT2, decreased to CACT1 and MDCT. Low contrast resolution increased between CACT2 and MDCT (P < 0.001). IQ was best for CACT2 (1.3 ± 0.5), decreased to CACT1 (1.9 ± 0.6) and MDCT (3.5 ± 0.6). Non-compromising artifacts were only reported for CACT. Conclusions: The results of this phantom and cadaveric study indicate that ultra-high resolution C-Arm CT arthrography of the wrist bears the potential to outperform MDCT arthrography in terms of image quality and workflow at the cost of mildly increasing image artifacts while radiation dose to the patient is comparably low for both, MDCT and C-Arm CT.

  7. PATTERN OF INTERSTITIAL LUNG DISEASE AS SEEN BY HIGH RESOLUTION COMPUTERISED TOMOGRAPHY.

    Science.gov (United States)

    Onyambu, C K; Waigwa, M N

    2012-09-01

    Diffuse lung diseases constitute a major cause of morbidity and mortality worldwide. High Resolution Computed Tomography (HRCT) is the recommended imaging technique in the diagnosis, assessment and followup of these diseases. To describe the pattern of HRCT findings in patients with suspected interstitial lung disease. Kenyatta National Hospital (KNH), Nairobi Hospital and MP Shah Hospital; all situated in Nairobi, during the period February to August 2010. One hundred and one patients sent for HRCT in the six month study period. A total of 101 patients were recruited with age range 18 to 100 years, with a mean age of 53.6 (SD 19.7) years and a median age of 54 years. The male-female ratio was 1.2:1. Cough [80.2% (n = 81)] was the most common presenting complaint followed by dyspnoea (53.5%, n = 53) and chest pain [24.8% (n = 25)]. Overall, the predominant pattern of involvement on chest HRCT was reticular pattern seen in 56.1% (n = 82) of patients, followed by honey-comb pattern (37.8%, n = 82). The study demonstrated marked lung parenchymal destruction in most cases; a poor prognostic indicator which could have been due to delayed referral. HRCT has a high pick up rate of subtle parenchymal lung lesions as well as defining the lesions and their distribution compared to plain chest radiography. This is important in narrowing the differential diagnosis as well as for pre-biopsy planning. The diagnosis of ILD requires a multidisciplinary approach including a detailed clinical history, physical findings, and laboratory investigations, radiological and histological assessment.

  8. Clinical cone beam computed tomography compared to high-resolution peripheral computed tomography in the assessment of distal radius bone.

    Science.gov (United States)

    de Charry, C; Boutroy, S; Ellouz, R; Duboeuf, F; Chapurlat, R; Follet, H; Pialat, J B

    2016-10-01

    Clinical cone beam computed tomography (CBCT) was compared to high-resolution peripheral quantitative computed tomography (HR-pQCT) for the assessment of ex vivo radii. Strong correlations were found for geometry, volumetric density, and trabecular structure. Using CBCT, bone architecture assessment was feasible but compared to HR-pQCT, trabecular parameters were overestimated whereas cortical ones were underestimated. HR-pQCT is the most widely used technique to assess bone microarchitecture in vivo. Yet, this technology has been only applicable at peripheral sites, in only few research centers. Clinical CBCT is more widely available but quantitative assessment of the bone structure is usually not performed. We aimed to compare the assessment of bone structure with CBCT (NewTom 5G, QR, Verona, Italy) and HR-pQCT (XtremeCT, Scanco Medical AG, Brüttisellen, Switzerland). Twenty-four distal radius specimens were scanned with these two devices with a reconstructed voxel size of 75 μm for Newtom 5G and 82 μm for XtremeCT, respectively. A rescaling-registration scheme was used to define the common volume of interest. Cortical and trabecular compartments were separated using a semiautomated double contouring method. Density and microstructure were assessed with the HR-pQCT software on both modality images. Strong correlations were found for geometry parameters (r = 0.98-0.99), volumetric density (r = 0.91-0.99), and trabecular structure (r = 0.94-0.99), all p < 0.001. Correlations were lower for cortical microstructure (r = 0.80-0.89), p < 0.001. However, absolute differences were observed between modalities for all parameters, with an overestimation of the trabecular structure (trabecular number, 1.62 ± 0.37 vs. 1.47 ± 0.36 mm(-1)) and an underestimation of the cortical microstructure (cortical porosity, 3.3 ± 1.3 vs. 4.4 ± 1.4 %) assessed on CBCT images compared to HR-pQCT images. Clinical CBCT devices are able to

  9. Pattern of interstitial lung disease detected by high resolution ...

    African Journals Online (AJOL)

    Background: Diffuse lung diseases constitute a major cause of morbidity and mortality worldwide. High Resolution Computed Tomography (HRCT) is the recommended imaging technique in the diagnosis, assessment and followup of these diseases. Objectives: To describe the pattern of HRCT findings in patients with ...

  10. Relationships (II) of International Classification of High-resolution Computed Tomography for Occupational and Environmental Respiratory Diseases with ventilatory functions indices for parenchymal abnormalities.

    Science.gov (United States)

    Tamura, Taro; Suganuma, Narufumi; Hering, Kurt G; Vehmas, Tapio; Itoh, Harumi; Akira, Masanori; Takashima, Yoshihiro; Hirano, Harukazu; Kusaka, Yukinori

    2015-01-01

    The International Classification of High-Resolution Computed Tomography (HRCT) for Occupational and Environmental Respiratory Diseases (ICOERD) is used to screen and diagnose respiratory illnesses. Using univariate and multivariate analysis, we investigated the relationship between subject characteristics and parenchymal abnormalities according to ICOERD, and the results of ventilatory function tests (VFT). Thirty-five patients with and 27 controls without mineral-dust exposure underwent VFT and HRCT. We recorded all subjects' occupational history for mineral dust exposure and smoking history. Experts independently assessed HRCT using the ICOERD parenchymal abnormalities (Items) grades for well-defined rounded opacities (RO), linear and/or irregular opacities (IR), and emphysema (EM). High-resolution computed tomography showed that 11 patients had RO; 15 patients, IR; and 19 patients, EM. According to the multiple regression model, age and height had significant associations with many indices ventilatory functions such as vital capacity, forced vital capacity, and forced expiratory volume in 1 s (FEV1). The EM summed grades on the upper, middle, and lower zones of the right and left lungs also had significant associations with FEV1 and the maximum mid-expiratory flow rate. The results suggest the ICOERD notation is adequate based on the good and significant multiple regression modeling of ventilatory function with the EM summed grades.

  11. A Computerized Tomography Study of Vocal Tract Setting in Hyperfunctional Dysphonia and in Belting.

    Science.gov (United States)

    Saldias, Marcelo; Guzman, Marco; Miranda, Gonzalo; Laukkanen, Anne-Maria

    2018-04-03

    Vocal tract setting in hyperfunctional patients is characterized by a high larynx and narrowing of the epilaryngeal and pharyngeal region. Similar observations have been made for various singing styles, eg, belting. The voice quality in belting has been described to be loud, speech like, and high pitched. It is also often described as sounding "pressed" or "tense". The above mentioned has led to the hypothesis that belting may be strenuous to the vocal folds. However, singers and teachers of belting do not regard belting as particularly strenuous. This study investigates possible similarities and differences between hyperfunctional voice production and belting. This study concerns vocal tract setting. Four male patients with hyperfunctional dysphonia and one male contemporary commercial music singer were registered with computerized tomography while phonating on [a:] in their habitual speaking pitch. Additionally, the singer used the pitch G4 in belting. The scannings were studied in sagittal and transversal dimensions by measuring lengths, widths, and areas. Various similarities were found between belting and hyperfunction: high vertical larynx position, small hypopharyngeal width, and epilaryngeal outlet. On the other hand, belting differed from dysphonia (in addition to higher pitch) by a wider lip and jaw opening, and larger volumes of the oral cavity. Belting takes advantage of "megaphone shape" of the vocal tract. Future studies should focus on modeling and simulation to address sound energy transfer. Also, they should consider aerodynamic variables and vocal fold vibration to evaluate the "price of decibels" in these phonation types. Copyright © 2018. Published by Elsevier Inc.

  12. Computerized tomographic evaluation of aortic prosthetic graft complications

    International Nuclear Information System (INIS)

    Kay, D.; Kalmar, J.A.

    1985-01-01

    Computerized tomography has been found to be an accurate and sensitive method of diagnosing complications of synthetic aortic grafts. Complications in this series of four cases included aortoesophageal fistula, aortoduodenal fistula, pseudoaneurysm, and retroperitoneal hematoma. 6 references, 5 figures

  13. Astronomy at high angular resolution a compendium of techniques in the visible and near-infrared

    CERN Document Server

    Hussain, Gaitee; Berger, Jean-Philippe; Schmidtobreick, Linda

    2016-01-01

    This book offers an essential compendium of astronomical high-resolution techniques. Recent years have seen considerable developments in such techniques, which are critical to advances in many areas of astronomy. As reflected in the book, these techniques can be divided into direct methods, interferometry, and reconstruction methods, and can be applied to a huge variety of astrophysical systems, ranging from planets, single stars and binaries to active galactic nuclei, providing angular resolution in the micro- to tens of milliarcsecond scales. Written by experts in their fields, the chapters cover adaptive optics, aperture masking imaging, spectra disentangling, interferometry, lucky imaging, Roche tomography, imaging with interferometry, interferometry of AGN, AGN reverberation mapping, Doppler- and magnetic imaging of stellar surfaces, Doppler tomography, eclipse mapping, Stokes imaging, and stellar tomography. This book is intended to enable a next generation of astronomers to apply high-resolution techni...

  14. ECAT: a new computerized tomographic imaging system for position-emitting radiopharmaceuticals

    International Nuclear Information System (INIS)

    Phelps, M.E.; Hoffman, E.J.; Huang, S.C.; Kuhl, D.E.

    1977-01-01

    The ECAT was designed and developed as a complete computerized positron radionuclide imaging system capable of providing high contrast, high resolution, quantitative images in 2 dimensional and tomographic formats. Flexibility, in its various image mode options, allows it to be used for a wide variety of imaging problems

  15. Ultra-High-Resolution Computed Tomography of the Lung: Image Quality of a Prototype Scanner

    Science.gov (United States)

    Kakinuma, Ryutaro; Moriyama, Noriyuki; Muramatsu, Yukio; Gomi, Shiho; Suzuki, Masahiro; Nagasawa, Hirobumi; Kusumoto, Masahiko; Aso, Tomohiko; Muramatsu, Yoshihisa; Tsuchida, Takaaki; Tsuta, Koji; Maeshima, Akiko Miyagi; Tochigi, Naobumi; Watanabe, Shun-ichi; Sugihara, Naoki; Tsukagoshi, Shinsuke; Saito, Yasuo; Kazama, Masahiro; Ashizawa, Kazuto; Awai, Kazuo; Honda, Osamu; Ishikawa, Hiroyuki; Koizumi, Naoya; Komoto, Daisuke; Moriya, Hiroshi; Oda, Seitaro; Oshiro, Yasuji; Yanagawa, Masahiro; Tomiyama, Noriyuki; Asamura, Hisao

    2015-01-01

    Purpose The image noise and image quality of a prototype ultra-high-resolution computed tomography (U-HRCT) scanner was evaluated and compared with those of conventional high-resolution CT (C-HRCT) scanners. Materials and Methods This study was approved by the institutional review board. A U-HRCT scanner prototype with 0.25 mm x 4 rows and operating at 120 mAs was used. The C-HRCT images were obtained using a 0.5 mm x 16 or 0.5 mm x 64 detector-row CT scanner operating at 150 mAs. Images from both scanners were reconstructed at 0.1-mm intervals; the slice thickness was 0.25 mm for the U-HRCT scanner and 0.5 mm for the C-HRCT scanners. For both scanners, the display field of view was 80 mm. The image noise of each scanner was evaluated using a phantom. U-HRCT and C-HRCT images of 53 images selected from 37 lung nodules were then observed and graded using a 5-point score by 10 board-certified thoracic radiologists. The images were presented to the observers randomly and in a blinded manner. Results The image noise for U-HRCT (100.87 ± 0.51 Hounsfield units [HU]) was greater than that for C-HRCT (40.41 ± 0.52 HU; P < .0001). The image quality of U-HRCT was graded as superior to that of C-HRCT (P < .0001) for all of the following parameters that were examined: margins of subsolid and solid nodules, edges of solid components and pulmonary vessels in subsolid nodules, air bronchograms, pleural indentations, margins of pulmonary vessels, edges of bronchi, and interlobar fissures. Conclusion Despite a larger image noise, the prototype U-HRCT scanner had a significantly better image quality than the C-HRCT scanners. PMID:26352144

  16. Ultra-High-Resolution Computed Tomography of the Lung: Image Quality of a Prototype Scanner.

    Directory of Open Access Journals (Sweden)

    Ryutaro Kakinuma

    Full Text Available The image noise and image quality of a prototype ultra-high-resolution computed tomography (U-HRCT scanner was evaluated and compared with those of conventional high-resolution CT (C-HRCT scanners.This study was approved by the institutional review board. A U-HRCT scanner prototype with 0.25 mm x 4 rows and operating at 120 mAs was used. The C-HRCT images were obtained using a 0.5 mm x 16 or 0.5 mm x 64 detector-row CT scanner operating at 150 mAs. Images from both scanners were reconstructed at 0.1-mm intervals; the slice thickness was 0.25 mm for the U-HRCT scanner and 0.5 mm for the C-HRCT scanners. For both scanners, the display field of view was 80 mm. The image noise of each scanner was evaluated using a phantom. U-HRCT and C-HRCT images of 53 images selected from 37 lung nodules were then observed and graded using a 5-point score by 10 board-certified thoracic radiologists. The images were presented to the observers randomly and in a blinded manner.The image noise for U-HRCT (100.87 ± 0.51 Hounsfield units [HU] was greater than that for C-HRCT (40.41 ± 0.52 HU; P < .0001. The image quality of U-HRCT was graded as superior to that of C-HRCT (P < .0001 for all of the following parameters that were examined: margins of subsolid and solid nodules, edges of solid components and pulmonary vessels in subsolid nodules, air bronchograms, pleural indentations, margins of pulmonary vessels, edges of bronchi, and interlobar fissures.Despite a larger image noise, the prototype U-HRCT scanner had a significantly better image quality than the C-HRCT scanners.

  17. Computerized tomography findings of acute traumatic epidural hematoma

    International Nuclear Information System (INIS)

    Kobayashi, Shiro; Nakazawa, Shozo; Yokota, Hiroyuki; Yajima, Kouzo; Yano, Masami; Otsuka, Toshibumi

    1984-01-01

    During four year period from April, 1977 to March, 1981, 53 cases with acute traumatic epidural hematoma had been encountered out of 430 acute head injured patients examined by computerized tomography (CT) within 24 hours after incurring the trauma. Besides the initial CT, the authors performed contrast enhanced CT (41 cases) and serial CT scanning (31 cases). There were 49 cases of epidural hematoma existing in the supratentorial region, Two cases infratentorial region and 2 cases in the both regions. Two cases of vertex epidural hematoma had been encountered, one of them required vertical scan technique. In 22 (41%) of the 53 patients, the initial CT showed evidence of other cerebral lesions. The most frequent lesion was pneumocephalus (11 cases), 3 cases of them existed in the epidural hematoma. There were also intracerebral hematoma (6 cases), subdural hematoma (4 cases), cerebral contusion (2 cases), intraventricular hemorrhage (2 cases) and 2 cases of them demonstrated ''diffuse traumatic cerebral injury''. During contrast enhanced CT, 11 cases out of 41 cases indicated several enhancement pattern. There were total enhancement of epidural hematoma (2 cases), partial enhancement of hematoma (2 cases) and enhancement of internal margin of hematoma (2 cases). Serial CT scans was performed in 36 out of the 53 patients. Common findings on the serial CT scans were decreased density collection in the subdural space such as subdural effusions or chronic subdural hematomas (8 cases) and enlargement of small epidural hematomas (3 cases). After evacuation of epidural hematoma, there were some cases showing the so-called ''delayed traumatic intracerebral hematoma'' (4 cases), appearance of other epidural hematoma (1 case) and development of small cerebral infarction in the basal ganglia. There was one case indicating appearance of a new epidural hematoma contra lateral to the side of evacuation of subdural hematoma. (J.P.N.)

  18. Efficacy of virtual computerized tomography laparoscopy for retroperitoneoscopic nephrectomy

    International Nuclear Information System (INIS)

    Shigeta, Masanobu; Kadonishi, Yuichi; Yasumoto, Hiroaki; Mita, Koji; Usui, Tsuguru; Marukawa, Kazushi

    2004-01-01

    Retroperitoneoscopic nephrectomy is less invasive than open nephrectomy, and is an alternative surgical procedure for renal tumors and upper urothelial tumors. We evaluated the efficacy of virtual computerized tomography laparoscopy (VCTL) as a navigator for retroperitoneoscopic nephrectomy to ascertain the correct anatomy of the renal hilum pre-operatively under the retroperitoneoscopic view. Seventy-three kidneys with localized renal tumors (n=44), upper urothelial tumors (n=23), or benign renal disease (n=6) underwent multidetector-row CT. VCTL was carried out by the volume-rendered technique. The findings were compared with those of real retroperitoneoscopy. After the operation, each operator scored 1 to 5 in evaluating the usefulness of virtual retroperitoneoscopy (score 5 indicated very useful). The percentages of renal arteries depicted by VCTL compared with those noted during real surgery were 93% for kidneys with renal tumors, 100% for upper urothelial tumors and 83% for benign renal disease. Two renal arteries of 2 kidneys were not detected by virtual imaging. These were about 1 mm in diameter and directly branched from the aorta, however retroperitoneoscopic nephrectomy was performed uneventfully. VCTL depicted all the renal veins. The anatomy of the renal hilum seen on VCTL and real retroperitoneoscopy was identical, without the minor angle deviation caused by drawing the kidney during the operation. The average score for the usefulness of VCTL was 4.1, ranging from 3 to 5. The accurate surgical anatomy of the renal hilum could be predicted in almost all patients pre-operatively. VCTL is an excellent navigator for retroperitoneoscopic nephrectomy. (author)

  19. What does the psychiatrist expect as to computerized tomography

    International Nuclear Information System (INIS)

    Huber, G.

    1980-01-01

    The computerized tomography (CT) can be applied also in psychiatry as an instrument of basic research. The problem of normative data as visualized by CT-scanning is up to now not yet satisfactory solved. Faulty appreciations especially on the cebral cortex in the sense of false-positive findings with possible serious social consequences are frequently. For judging of brain cortex as to atrophy primarily more basically situated sulci in various slices are taken into consideration, while the sulci of upper slices near the vertex just as the representations of cisterns, the interhemispheric fissure and Pacchionian granulations should not to be evaluated. On a new revision of the subject cerebral atrophy and irreversible psychosyndrome it is necessary and useful to compare the results of CT-scanning with those of pneumoencephalographic studies. The favourable possibilities which the CT offers also for diagnostic and research in psychiatry are to be used by critical appreciation of already existing experiences. The indication fpr TC requires complete psychiatric-neurological investigation. The interpretation of findings and the attempts to correlate them with the clinical data must take place in close cooperation with the clinical psychiatry. The neuroradiological evidence of cerebral atrophy can give hints concerning the diagnosis and prognosis only in connection with all clinical data. Findings of cerebral atrophy, combined cortical and subcortical, exclusively subcortical of preferably on the 3rd ventricle are non-specific and not characteristic of a certain disease. There are only correlations between certain types of cerebral atrophy and certain types of irreversible psychopathological syndromes. (orig.) [de

  20. Segmentation methodology for automated classification and differentiation of soft tissues in multiband images of high-resolution ultrasonic transmission tomography.

    Science.gov (United States)

    Jeong, Jeong-Won; Shin, Dae C; Do, Synho; Marmarelis, Vasilis Z

    2006-08-01

    This paper presents a novel segmentation methodology for automated classification and differentiation of soft tissues using multiband data obtained with the newly developed system of high-resolution ultrasonic transmission tomography (HUTT) for imaging biological organs. This methodology extends and combines two existing approaches: the L-level set active contour (AC) segmentation approach and the agglomerative hierarchical kappa-means approach for unsupervised clustering (UC). To prevent the trapping of the current iterative minimization AC algorithm in a local minimum, we introduce a multiresolution approach that applies the level set functions at successively increasing resolutions of the image data. The resulting AC clusters are subsequently rearranged by the UC algorithm that seeks the optimal set of clusters yielding the minimum within-cluster distances in the feature space. The presented results from Monte Carlo simulations and experimental animal-tissue data demonstrate that the proposed methodology outperforms other existing methods without depending on heuristic parameters and provides a reliable means for soft tissue differentiation in HUTT images.

  1. Flat-Panel Computed Tomography (DYNA-CT) in Neuroradiology. From High-Resolution Imaging of Implants to One-Stop-Shopping for Acute Stroke.

    Science.gov (United States)

    Doerfler, A; Gölitz, P; Engelhorn, T; Kloska, S; Struffert, T

    2015-10-01

    Originally aimed at improving standard radiography by providing higher absorption efficiency and a wider dynamic range, flat-panel detector technology has meanwhile got widely accepted in the neuroradiological community. Especially flat-panel detector computed tomography (FD-CT) using rotational C-arm mounted flat-panel detector technology is capable of volumetric imaging with a high spatial resolution. By providing CT-like images of the brain within the angio suite, FD-CT is able to rapidly visualize hemorrhage and may thus improve complication management without the need of patient transfer. As "Angiographic CT" FD-CT may be helpful during many diagnostic and neurointerventional procedures and for noninvasive monitoring and follow-up. In addition, spinal interventions and high-resolution imaging of the temporal bone might also benefit from FD-CT. Finally, using novel dynamic perfusion and angiographic protocols, FD-CT may provide functional information on brain perfusion and vasculature with the potential to replace standard imaging in selected acute stroke patients.

  2. Intracranial arterial anatomy: evaluation by computed tomography angiography

    International Nuclear Information System (INIS)

    Regattieri, Neysa Aparecida Tinoco; Haetinger, Rainer Guilherme; Liberti, Edson Aparecido

    2010-01-01

    By many decades, the intracranial arteries study was realized exclusively by angiography through selective arterial catheterization. Nowadays, with the technologic evaluation of computerized tomography devices with multi detectors allowing acquisitions with even more thinner slices, higher speed and better resolution, it had appeared a new modality of investigation: the computed tomography angiography, less invasive and with minor morbidity than conventional arteriography. Many studies in the literature have been analyzing the sensibility of the new method for the detection of intracranial aneurysms and comparing them with the conventional arteriography. There is a necessity to recognize the normal intracranial arterial anatomy and its variations using images obtained from multiplanar reformations, in order to give important information for surgeries strategies, such as wall calcifications, aneurismatic neck position and relationships with surrounding anatomical structures. (author)

  3. Cardiac Computed Tomography (Multidetector CT, or MDCT)

    Science.gov (United States)

    ... Disease Venous Thromboembolism Aortic Aneurysm More Cardiac Computed Tomography (Multidetector CT, or MDCT) Updated:Sep 19,2016 What is Computerized Tomography (CT)? CT is a noninvasive test that uses ...

  4. Rostrocaudal gradients of dopamine D2/3 receptor binding in striatal subregions measured with [11C]raclopride and high-resolution positron emission tomography

    DEFF Research Database (Denmark)

    Alakurtti, Kati; Johansson, Jarkko J; Tuokkola, Terhi

    2013-01-01

    scanned with brain-dedicated high-resolution research tomography (HRRT, Siemens Medical Solutions, Knoxville, TN, USA) and [(11)C]raclopride. Coronally defined regions of interest (ROIs) of the caudate nucleus, putamen and ventral striatum (VST) were sampled plane-by-plane, 1.5mm apart, on spatially...... observed in the VST. The novelty of this study lies in the presentation, for the first time, of the D2/3 receptor binding gradients in each striatal subregion in the brains of living healthy humans. The high spatial resolution provided by HRRT enables frequent sampling of BPND along the longitudinal extent...

  5. Computerized tomography using fast neutrons

    International Nuclear Information System (INIS)

    Maier-Schuler, P.

    1992-03-01

    The equipment is transportable and can be used at different neutron sources. CT-images are presented showing that it is possible to get good results by using CT with fast neutrons in non destructive testing. Small defects with high contrasts can be detected as well as larger defects with small differences in material density. Since the neutrons interact with the nuclei and not with the electron density the CT-images contain different information compared with X-ray or γ images. As neutron sources always emit γ-radiation too, this radiation can be detected simultaneously with the neutrons. Therefore one can get a γ CT-image along with the neutron image. For the examination of small samples or objects containing materials with great differences in the linear attenuation coefficients like Al and H 2 thermal neutrons have been used for CT-measurements too. A spatial resolution and a density resolution of 0.1 mm and about 5% respectively could be achieved in the CT-images with fast neutrons and 0.04 mm with thermal neutrons. (orig./HP) [de

  6. A resolution-enhancing image reconstruction method for few-view differential phase-contrast tomography

    Science.gov (United States)

    Guan, Huifeng; Anastasio, Mark A.

    2017-03-01

    It is well-known that properly designed image reconstruction methods can facilitate reductions in imaging doses and data-acquisition times in tomographic imaging. The ability to do so is particularly important for emerging modalities such as differential X-ray phase-contrast tomography (D-XPCT), which are currently limited by these factors. An important application of D-XPCT is high-resolution imaging of biomedical samples. However, reconstructing high-resolution images from few-view tomographic measurements remains a challenging task. In this work, a two-step sub-space reconstruction strategy is proposed and investigated for use in few-view D-XPCT image reconstruction. It is demonstrated that the resulting iterative algorithm can mitigate the high-frequency information loss caused by data incompleteness and produce images that have better preserved high spatial frequency content than those produced by use of a conventional penalized least squares (PLS) estimator.

  7. High resolution techniques using scanning proton microprobe (SPM)

    International Nuclear Information System (INIS)

    Cholewa, M.; Saint, A.; Prawer, S.; Laird, J.S.; Legge, G.J.F.; Bardos, R.A.; Moorhead, G.F.; Taylor, G.N.; Stuart, S.A.; Howard, J.

    1994-01-01

    The very high resolution (down to 50 nm) achieved with low beam currents (fA) in a scanning ion microprobe have lead to many nondestructive techniques of microanalysis. This paper discusses recent developments and applications in the use of 3-D STIM (scanning transmission ion microscopy) Tomography, channeling STIM and IBIC (ion beam induced charge). (orig.)

  8. [Diagnostic value of high-resolution computed tomography imaging in congenital inner ear malformations].

    Science.gov (United States)

    Sun, Xiaowei; Ding, Yuanping; Zhang, Jianji; Chen, Ying; Xu, Anting; Dou, Fenfen; Zhang, Zihe

    2007-02-01

    To observe the inner ear structure with volume rendering (VR) reconstruction and to evaluate the role of high-resolution computed tomography (HRCT) in congenital inner ear malformations. HRCT scanning was performed in 10 patients (20 ears) without ear disease (control group) and 7 patients (11 ears) with inner ear malformations (IEM group) and the original data was processed with VR reconstruction. The inner ear osseous labyrinth structure in the images generated by these techniques was observed respectively in the normal ears and malformation ears. The inner ear osseous labyrinth structure and the relationship was displayed clearly in VR imaging in the control group,meanwhile, characters and degree of malformed structure were also displayed clearly in the IEA group. Of seven patients (11 ears) with congenital inner ear malformations, the axial, MPR and VR images can display the site and degree in 9 ears. VR images were superior to the axial images in displaying the malformations in 2 ears with the small lateral semicircular canal malformations. The malformations included Mondini deformity (7 ears), vestibular and semicircular canal malformations (3 ears), vestibular aqueduct dilate (7 ears, of which 6 ears accompanied by other malformations) , the internal auditory canal malformation (2 ears, all accompanied by other malformations). HRCT can display the normal structure of bone inner ear through high quality VR reconstructions. VR images can also display the site and degree of the malformations three-dimensionally and intuitively. HRCT is valuable in diagnosing the inner ear malformation.

  9. Computerized axial tomography of the chest for visualization of ''absent'' pulmonary arteries

    Energy Technology Data Exchange (ETDEWEB)

    Sondheimer, H.M. (Upstate Medical Center, Syracuse, NY); Oliphant, M.; Schneider, B.; Kavey, R.E.W.; Blackman, M.S.; Parker, F.B. Jr.

    1982-05-01

    To expand the search for central pulmonary arteries in six patients with absence of cardiac-pulmonary continuity, computerized axial tomography (CAT) of the chest was performed. The CAT scans were compared with previous arteriograms and pulmonary vein wedge angiograms. Three patients with type IV truncus arteriosus were studied, and none had a central, right or left pulmonary artery on CAT scan. However, two patients with tetralogy of Fallot with pulmonary atresia and a patent ductus arteriosus to the right lung demonstrated the presence of a left pulmonary artery. In addition, one child with truncus arteriosus with ''absent'' left pulmonary artery demonstrated a left pulmonary artery on the CAT scan. The CAT scan may therefore enhance our ability to search for disconnected pulmonary arteries in children with complex cyanotic congenital heart disease.

  10. Indirect computerized tomography sign of chronic subdural hematoma demonstrated in the posterior fossa

    Energy Technology Data Exchange (ETDEWEB)

    Machi, Takao; Fukui, Masashi; Maeyama, Ryutaro; Takaki, Tosuke; Yoshiura, Shogo; Kamoi, Itsuma

    1985-03-01

    In cases of chronic subdural hematoma (CSH), brain computerized tomography (CT) scans frequently disclose a low density band in the posterior fossa (LDBP) between the lateral margin of the cerebellum and the adjacent petrous bone/tentorium cerebelli. Out of 121 cases of CSH, 56 (46%) showed the LDBP. The LDBP was mostly ipsilateral to the side of the CSH or bilateral. The frequency of the LDBP had no correlation with the severity of the cerebral midline shift or the thickness of the hematoma. As normal controls, CT scans of 257 cases in which no organic lesions were detected were used. Also 30 cases with dementing diseases, 2 cases with spinocerebellar degeneration and 428 cases of other neurological diseases such as head trauma other than CSH, brain tumor, cerebrovascular disease etc. were studied as disease controls. The incidence of the LDBP in both controls was significantly lower than in CSH. Therefore, the LDBP in cases of CSH was considered to be a significant associated finding of CT scans. The mechanism of the LDBP is discussed.

  11. Dosimetry in computerized tomography and evaluation of doses in organs in thorax scanning

    International Nuclear Information System (INIS)

    Alonso, Thêssa Cristina

    2016-01-01

    Computed tomography has promoted improvement of the diagnostic process by producing anatomical cut images with high quality and contrast between soft tissues which have very similar absorption of the X-ray beams. The objective of this study is to evaluate the technological park of CT in Brazil correlated with the wide world, and carry out studies of experimental dosimetry to understand the dose distribution feature using phantoms and different methods of measurement of kerma index, as well as perform measures of local doses in sensitive organs. To study the scanner geographic distribution and supply of computed tomography tests in Brazil, a comparison has been made with results found with the specified reference by Brazilian law (Ordinance GM / MS No. 1101, 2002; Resolution RE nº1016, 2006). For dosimetry studies, It was used a standard chest phantom and the anthropomorphic phantom. For image quality evaluation, it was used the CATPHAN-600 phantom. Scans were performed in a GE scanner, Discovery model with 64 channels. Dose measurements have been performed by using a pencil ionization chamber, thermoluminescent dosimeters and radiochromic film strips. Sensitive organ shielding devices were evaluated in order to verify their efficiency in organ dose reduction and its influence in the quality of image. Considering Brazilian population, the scanner park showed a greater amount than the minimum parameter recommended by Brazilian law. Dose measurements using three different methods showed the correct procedure of metrological reliability of the measurement system. The findings and conclusions of this study may contribute to the improvement of local practices in Computed Tomography tests, inserted in context of radiological protection in order to define reference levels for optimized diagnosis, and image quality control. (author)

  12. Resting state rCBF mapping with single-photon emission tomography and positron emission tomography: magnitude and origin of differences

    International Nuclear Information System (INIS)

    Jonsson, C.; Kimiaei, S.; Larsson, S.A.; Pagani, M.; Ingvar, M.; Thurfjell, L.; Jacobsson, H.

    1998-01-01

    Single-photon emission tomography (SPET), using technetium-99m hexamethylpropylene amine oxime, and positron emission tomography (PET), using oxygen-15 butanol were compared in six healthy male volunteers with regard to the mapping of resting state regional cerebral blood flow (rCBF). A computerized brain atlas was utilized for 3D regional analyses and comparison of 64 selected and normalized volumes of interest (VOIs). The normalized mean rCBF values in SPET, as compared to PET, were higher in most of the Brodmann areas in the frontal and parietal lobes (4.8% and 8.7% respectively). The average differences were small in the temporal (2.3%) and occipital (1.1%) lobes. PET values were clearly higher in small VOIs like the thalamus (12.3%), hippocampus (12.3%) and basal ganglia (9.9%). A resolution phantom study showed that the in-plane SPET/PET system resolution was 11.0/7.5 mm. In conclusion, SPET and PET data demonstrated a fairly good agreement despite the superior spatial resolution of PET. The differences between SPET and PET rCBF are mainly due to physiological and physical factors, the data processing, normalization and co-registration methods. In order to further improve mapping of rCBF with SPET it is imperative not only to improve the spatial resolution but also to apply accurate correction techniques for scatter, attenuation and non-linear extraction. (orig.)

  13. The Pattern of Significant Lesions Found in Computerized ...

    African Journals Online (AJOL)

    Introduction: Seizures are common reasons for neurologic consultations and investigations. In the absence of magnetic resonance imaging, computerized tomography scanning of the brain is a reliable and cheaper alternative. Little is known about the pattern of brain lesions in patients with recurrent seizures in Nigeria.

  14. High resolution CT of temporal bone trauma

    International Nuclear Information System (INIS)

    Youn, Eun Kyung

    1986-01-01

    Radiographic studies of the temporal bone following head trauma are indicated when there is cerebrospinal fluid otorrhea or rhinorrhoea, hearing loss, or facial nerve paralysis. Plain radiography displays only 17-30% of temporal bone fractures and pluridirectional tomography is both difficult to perform, particularly in the acutely ill patient, and less satisfactory for the demonstration of fine fractures. Consequently, high resolution CT is the imaging method of choice for the investigation of suspected temporal bone trauma and allows special resolution of fine bony detail comparable to that attainable by conventional tomography. Eight cases of temporal bone trauma examined at Korea General Hospital April 1985 through May 1986. The results were as follows: Seven patients (87%) suffered longitudinal fractures. In 6 patients who had purely conductive hearing loss, CT revealed various ossicular chain abnormality. In one patient who had neuro sensory hearing loss, CT demonstrated intract ossicular with a fracture nearing lateral wall of the lateral semicircular canal. In one patient who had mixed hearing loss, CT showed complex fracture.

  15. Micromotor endoscope catheter for in vivo, ultrahigh-resolution optical coherence tomography

    Science.gov (United States)

    Herz, P. R.; Chen, Y.; Aguirre, A. D.; Schneider, K.; Hsiung, P.; Fujimoto, J. G.; Madden, K.; Schmitt, J.; Goodnow, J.; Petersen, C.

    2004-10-01

    A distally actuated, rotational-scanning micromotor endoscope catheter probe is demonstrated for ultrahigh-resolution in vivo endoscopic optical coherence tomography (OCT) imaging. The probe permits focus adjustment for visualization of tissue morphology at varying depths with improved transverse resolution compared with standard OCT imaging probes. The distal actuation avoids nonuniform scanning motion artifacts that are present with other probe designs and can permit a wider range of imaging speeds. Ultrahigh-resolution endoscopic imaging is demonstrated in a rabbit with micromotor endoscope catheter probe promises to improve OCT imaging performance in future endoscopic imaging applications.

  16. Significance of cranial computerized tomography for diagnosis and therapy of inflammatory diseases of the brain and meninges in children

    Energy Technology Data Exchange (ETDEWEB)

    Kotlarek, F; Hauke, P; Zeumer, H [Technische Hochschule Aachen (Germany, F.R.). Abt. Kinderheilkunde; Technische Hochschule Aachen (Germany, F.R.). Abt. Neurologie)

    1979-01-01

    The significance of cranial computerized tomography (CCT) for the diagnosis and therapy of inflammatory diseases of the central nervous system in children is discussed in connection with five characteristic case studies. CCT is shown to be superior to classical neuroradiological approaches, and to allow important diagnostic insights: 1. the early recognition of diffuse brain edema and the resulting possibility of an early begin of therapy - 2. the pathological expansions of the cerebral ventricles of various etiology before a pathological enlargement of the head can be detected, and the size of the ventricles after neurosurgical therapy can be measured - 3. the early recognition of space-occupying inflammatory complications.

  17. Echography and computed tomography in the diagnosis of gastric leiomyoma

    International Nuclear Information System (INIS)

    Bujlov, V.M.; Borisanov, A.V.; Bessarab, A.V.

    1998-01-01

    Case of the diagnosis of gastric leiomyoma identified by ultrasonic scanning (USS) and computerized tomography (CT) (X-ray and endoscopic data are negative) is described. Presented observation shows the high efficiency of transabdominal USS and CT in revealing exogastric neoplasm

  18. SUPER-RESOLUTION ULTRASOUND TOMOGRAPHY: A PRELIMINARY STUDY WITH A RING ARRAY

    Energy Technology Data Exchange (ETDEWEB)

    HUANG, LIANJIE [Los Alamos National Laboratory; SIMONETTI, FRANCESCO [NON LANL; DURIC, NEBOJSA [NON LANL; RAMA, OLSI [NON LANL

    2007-01-18

    Ultrasound tomography attempts to retrieve the structure of an objective by exploiting the interaction of acoustic waves with the object. A fundamental limit of ultrasound tomography is that features cannot be resolved if they are spaced less than {lambda}/2 apart, where {lambda} is wavelength of the probing wave, regardless of the degree of accuracy of the measurements. Therefore, since the attenuation of the probing wave with propagation distance increases as {lambda} decreases, resolution has to be traded against imaging depth. Recently, it has been shown that the {lambda}/2 limit is a consequence of the Born approximation (implicit in the imaging algorithms currently employed) which neglects the distortion of the probing wavefield as it travels through the medium to be imaged. On the other hand, such a distortion, which is due to the multiple scattering phenomenon, can encode unlimited resolution in the radiating component of the scattered field. Previously, a resolution better than {lambda}/3 has been reported in these proceedings [F. Simonetti, pp. 126 (2006)] in the case of elastic wave probing. In this paper, they demonstrate experimentally a resolution better than {lambda}/4 for objects immersed in a water bth probed by means of a ring array which excites and detects pressure waves in a full view configuration.

  19. The Pattern of Significant Lesions Found in Computerized ...

    African Journals Online (AJOL)

    2017-12-05

    Dec 5, 2017 ... Introduction: Seizures are common reasons for neurologic consultations and investigations. In the absence of magnetic resonance imaging, computerized tomography scanning of the brain is a reliable and cheaper alternative. Little is known about the pattern of brain lesions in patients with recurrent ...

  20. Study on the performance of large area MRPC with high position resolution

    Energy Technology Data Exchange (ETDEWEB)

    Yue Qian, E-mail: yueq@mail.tsinghua.edu.cn [Department of Engineering Physics, Tsinghua University, Beijing 100084 (China); Key Laboratory of Particle and Radiation Imaging, Tsinghua University, Ministry of Education (China); Wu Yucheng; Li Yuanjing; Ye Jin; Cheng Jianping; Wang Yi; Li Jin [Department of Engineering Physics, Tsinghua University, Beijing 100084 (China); Key Laboratory of Particle and Radiation Imaging, Tsinghua University, Ministry of Education (China)

    2012-01-01

    Multi-gap resistive plate chamber (MRPC), which is mostly developed in high energy physics domain with excellent time resolution, is also highlighted in imaging applications. A set of 50 cm Multiplication-Sign 50 cm large area MRPC with high position resolution was successfully developed by our group and different experiments have been done to test its performances. Cosmic ray muons were used to do the test and proper high voltage and working gas were chosen. Data analysis indicates its good detection efficiency and good position resolution, which encourages further study of its application in RPC-PET and muon tomography.

  1. Effects of pure and hybrid iterative reconstruction algorithms on high-resolution computed tomography in the evaluation of interstitial lung disease.

    Science.gov (United States)

    Katsura, Masaki; Sato, Jiro; Akahane, Masaaki; Mise, Yoko; Sumida, Kaoru; Abe, Osamu

    2017-08-01

    To compare image quality characteristics of high-resolution computed tomography (HRCT) in the evaluation of interstitial lung disease using three different reconstruction methods: model-based iterative reconstruction (MBIR), adaptive statistical iterative reconstruction (ASIR), and filtered back projection (FBP). Eighty-nine consecutive patients with interstitial lung disease underwent standard-of-care chest CT with 64-row multi-detector CT. HRCT images were reconstructed in 0.625-mm contiguous axial slices using FBP, ASIR, and MBIR. Two radiologists independently assessed the images in a blinded manner for subjective image noise, streak artifacts, and visualization of normal and pathologic structures. Objective image noise was measured in the lung parenchyma. Spatial resolution was assessed by measuring the modulation transfer function (MTF). MBIR offered significantly lower objective image noise (22.24±4.53, PASIR (39.76±7.41) and FBP (51.91±9.71). MTF (spatial resolution) was increased using MBIR compared with ASIR and FBP. MBIR showed improvements in visualization of normal and pathologic structures over ASIR and FBP, while ASIR was rated quite similarly to FBP. MBIR significantly improved subjective image noise (PASIR and FBP. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. Computerized ECT data analysis system

    International Nuclear Information System (INIS)

    Miyake, Y.; Fukui, S.; Iwahashi, Y.; Matsumoto, M.; Koyama, K.

    1988-01-01

    For the analytical method of the eddy current testing (ECT) of steam generator tubes in nuclear power plants, the authors have developed the computerized ECT data analysis system using a large-scale computer with a high-resolution color graphic display. This system can store acquired ECT data up to 15 steam generators, and ECT data can be analyzed immediately on the monitor in dialogue communication with a computer. Analyzed results of ECT data are stored and registered in the data base. This system enables an analyst to perform sorting and collecting of data under various conditions and obtain the results automatically, and also to make a plan of tube repair works. This system has completed the test run, and has been used for data analysis at the annual inspection of domestic plants. This paper describes an outline, features and examples of the computerized eddy current data analysis system for steam generator tubes in PWR nuclear power plants

  3. Resolution tests of global geodynamic models by travel-time tomography

    Czech Academy of Sciences Publication Activity Database

    Běhounková, Marie; Čížková, H.; Matyska, C.

    2005-01-01

    Roč. 49, č. 3 (2005), s. 343-363 ISSN 0039-3169 R&D Projects: GA ČR GA205/02/1306 Institutional research plan: CEZ:AV0Z30120515 Keywords : seismic tomography * synthetic inversion * resolution tests Subject RIV: DC - Siesmology, Volcanology, Earth Structure Impact factor: 0.656, year: 2005

  4. Computerized tomography in diagnosis of cerebrocranial injury

    International Nuclear Information System (INIS)

    Kornienko, V.N.; Vasin, N.Ya.; Kuz'menko, V.A.

    1987-01-01

    The method of computerized tomographical examination are presented. Th KT-characters of concussion of the brain, its contusion of different severity, compressions in case of traumatic intracranial hematomas, contusion injuries, brain edema and different aftereffects of cerebrocranial injury are given. On the basis of comparison of the data of clinical and KT examination the dynamics of intracranial traumatic injuries in the course of treatment is described. The problems of therapeutic and surgical tactics depending on the degree and form of intracranial structure injuries and the phase of clinical course of posttraumatic process are discussed

  5. Accurate determination of high-risk coronary lesion type by multidetector cardiac computed tomography.

    Science.gov (United States)

    Alasnag, Mirvat; Umakanthan, Branavan; Foster, Gary P

    2008-07-01

    Coronary arteriography (CA) is the standard method to image coronary lesions. Multidetector cardiac computerized tomography (MDCT) provides high-resolution images of coronary arteries, allowing a noninvasive alternative to determine lesion type. To date, no studies have assessed the ability of MDCT to categorize coronary lesion types. The objective of this study was to determine the accuracy of lesion type categorization by MDCT using CA as a reference standard. Patients who underwent both MDCT and CA within 2 months of each other were enrolled. MDCT and CA images were reviewed in a blinded fashion. Lesions were categorized according to the SCAI classification system (Types I-IV). The origin, proximal and middle segments of the major arteries were analyzed. Each segment comprised a data point for comparison. Analysis was performed using the Spearman Correlation Test. Four hundred eleven segments were studied, of which 110 had lesions. The lesion distribution was as follows: 35 left anterior descending (LAD), 29 circumflex (Cx), 31 right coronary artery (RCA), 2 ramus intermedius, 8 diagonal, 4 obtuse marginal and 2 left internal mammary arteries. Correlations between MDCT and CA were significant in all major vessels (LAD, Cx, RCA) (p < 0.001). The overall correlation coefficient was 0.67. Concordance was strong for lesion Types II-IV (97%) and poor for Type I (30%). High-risk coronary lesion types can be accurately categorized by MDCT. This ability may allow MDCT to play an important noninvasive role in the planning of coronary interventions.

  6. Can high-resolution peripheral quantitative computed tomography imaging of subchondral and cortical bone predict condylar fracture in Thoroughbred racehorses?

    Science.gov (United States)

    Trope, G D; Ghasem-Zadeh, A; Anderson, G A; Mackie, E J; Whitton, R C

    2015-07-01

    High-resolution 3D imaging may improve the prediction and/or early identification of condylar fractures of the distal metacarpus/tarsus and reduce the frequency of breakdown injury in racehorses. To test the hypotheses that horses suffering condylar fractures have higher bone volume fraction (BV/TV) of the distal metacarpal epiphysis, greater subchondral bone thickness at the fracture site and higher second moment of inertia in the metacarpal midshaft as identified with high-resolution 3D imaging. Cross-sectional study using cadaver material. Thoroughbreds that died on racetracks were grouped as: 1) horses with third metacarpal (McIII) fractures with a condylar component (cases, n = 13); 2) horses with no limb fracture (controls, n = 8); 3) horses with fractures in other bones or suspensory apparatus disruption (other fatal injuries, n = 16). The palmar condyles of McIII and the midshaft were examined with high resolution peripheral quantitative computed tomography (HR-pQCT). Statistical analysis included logistic regression and Spearman's correlation. There were no significant differences in BV/TV of distal McIII and second moment of inertia of the midshaft between cases and controls. Epiphyseal bone BV/TV was greater in injured limbs of horses with any fatal limb injury (Groups 1 and 3 combined) compared with controls (odds ratio = 1.20, 95% confidence interval 1.01-1.42, P = 0.034). An epiphyseal BV/TV>0.742 resulted in a sensitivity of 82.8% and specificity of 62.5% in identifying horses with fatal limb injury. In horses without condylar fracture, increased subchondral bone thickness was associated with palmar osteochondral disease lesions in the adjacent condyle (rs = 0.65, Phorses at risk of any fatal breakdown injury but not metacarpal condylar fractures. Measurement of parasagittal groove subchondral bone thickness is complicated by adjacent palmar osteochondral disease lesions. Thus, high-resolution imaging of the distal metacarpus appears to have limited

  7. Development of direct observation aparatus of coal carbonization process by x-ray computerized tomography method

    International Nuclear Information System (INIS)

    Sakawa, Mitsuhiro; Shiraishi, Katsuhiko; Sakurai, Yoshihisa; Shimomura, Yasuto

    1987-01-01

    Coke production by chamber ovens has a long history and efforts are being continued to make the manufacturing process efficient and to preserve the environment. In this production by this method, however, it is hardly possible to obtain direct information during coal carbonization. Since the elements that compose coal and coke are carbon, hydrogen, oxygen, etc. and are similar to those of the human body, authors has developed a coke oven that permits the direct observation of the coal carbonization process using a soft X-ray computerized tomography (CT) apparatus used in medical treatment. The following phenomena can be observed as images by the coke oven for the CT method : 1) Changes in the bulk density of charge coal (including the difference in the water content), 2) Width of the plastic layer and movement of the plastic layer in the coke oven chamber, 3) Expansion and shrinkage of the charge in the coke oven chamber, 4) Initiation and growth of cracks. (author)

  8. Gas scintillation glass GEM detector for high-resolution X-ray imaging and CT

    Energy Technology Data Exchange (ETDEWEB)

    Fujiwara, T., E-mail: fujiwara-t@aist.go.jp [Research Institute for Measurement and Analytical Instrumentation, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki 305-8568 (Japan); Mitsuya, Y. [Nuclear Professional School, The University of Tokyo, Tokai, Naka, Ibaraki 319-1188 (Japan); Fushie, T. [Radiment Lab. Inc., Setagaya, Tokyo 156-0044 (Japan); Murata, K.; Kawamura, A.; Koishikawa, A. [XIT Co., Naruse, Machida, Tokyo 194-0045 (Japan); Toyokawa, H. [Research Institute for Measurement and Analytical Instrumentation, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki 305-8568 (Japan); Takahashi, H. [Institute of Engineering Innovation, School of Engineering, The University of Tokyo, Bunkyo, Tokyo 113-8654 (Japan)

    2017-04-01

    A high-spatial-resolution X-ray-imaging gaseous detector has been developed with a single high-gas-gain glass gas electron multiplier (G-GEM), scintillation gas, and optical camera. High-resolution X-ray imaging of soft elements is performed with a spatial resolution of 281 µm rms and an effective area of 100×100 mm. In addition, high-resolution X-ray 3D computed tomography (CT) is successfully demonstrated with the gaseous detector. It shows high sensitivity to low-energy X-rays, which results in high-contrast radiographs of objects containing elements with low atomic numbers. In addition, the high yield of scintillation light enables fast X-ray imaging, which is an advantage for constructing CT images with low-energy X-rays.

  9. Radiologist agreement on the quantification of bronchiectasis by high-resolution computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    Brito, Milene Carneiro Barbosa de, E-mail: milenebrito7@gmail.com [Clinica da Imagem do Tocantins, Araguaia, TO (Brazil); Ota, Mauricio Kenji [Fundacao Instituto de Pesquisa e Estudos de Diagnostico por Imagem (FIDI), Sao Paulo, SP (Brazil); Leitao Filho, Fernando Sergio Studart [Universidade de Fortaleza (UNIFOR), Fortaleza, CE (Brazil); Meirelles, Gustavo de Souza Portes [Grupo Fleury, Sao Paulo, SP (Brazil)

    2017-01-15

    Objective: To evaluate radiologist agreement on the quantification of bronchiectasis by high-resolution computed tomography (HRCT). Materials and Methods: The HRCT scans of 43 patients with bronchiectasis were analyzed by two radiologists, who used a scoring system to grade the findings. Kappa (κ) values and overall agreement were calculated. Results: For the measurement and appearance of bronchiectasis, the interobserver agreement was moderate (κ = 0.45 and κ = 0.43, respectively), as was the intraobserver agreement (κ = 0.54 and κ = 0.47, respectively). Agreement on the presence of mucous plugging was fair, for central distribution (overall interobserver agreement of 68.3% and κ = 0.39 for intraobserver agreement) and for peripheral distribution (κ = 0.34 and κ = 0.35 for interobserver and intraobserver agreement, respectively). The agreement was also fair for peri bronchial thickening (κ = 0.21 and κ = 0.30 for interobserver and intraobserver agreement, respectively). There was fair interobserver and intraobserver agreement on the detection of opacities (κ = 0.39 and 71.9%, respectively), ground-glass attenuation (64.3% and κ = 0.24, respectively), and cysts/bullae (κ = 0.47 and κ = 0.44, respectively). Qualitative analysis of the HRCT findings of bronchiectasis and the resulting individual patient scores showed that there was an excellent correlation between the observers (intra class correlation coefficient of 0.85 and 0.81 for interobserver and intraobserver agreement, respectively). Conclusion: In the interpretation of HRCT findings of bronchiectasis, radiologist agreement appears to be fair. In our final analysis of the findings using the proposed score, we observed excellent interobserver and intraobserver agreement. (author)

  10. Radiologist agreement on the quantification of bronchiectasis by high-resolution computed tomography

    International Nuclear Information System (INIS)

    Brito, Milene Carneiro Barbosa de; Ota, Mauricio Kenji; Leitao Filho, Fernando Sergio Studart; Meirelles, Gustavo de Souza Portes

    2017-01-01

    Objective: To evaluate radiologist agreement on the quantification of bronchiectasis by high-resolution computed tomography (HRCT). Materials and Methods: The HRCT scans of 43 patients with bronchiectasis were analyzed by two radiologists, who used a scoring system to grade the findings. Kappa (κ) values and overall agreement were calculated. Results: For the measurement and appearance of bronchiectasis, the interobserver agreement was moderate (κ = 0.45 and κ = 0.43, respectively), as was the intraobserver agreement (κ = 0.54 and κ = 0.47, respectively). Agreement on the presence of mucous plugging was fair, for central distribution (overall interobserver agreement of 68.3% and κ = 0.39 for intraobserver agreement) and for peripheral distribution (κ = 0.34 and κ = 0.35 for interobserver and intraobserver agreement, respectively). The agreement was also fair for peri bronchial thickening (κ = 0.21 and κ = 0.30 for interobserver and intraobserver agreement, respectively). There was fair interobserver and intraobserver agreement on the detection of opacities (κ = 0.39 and 71.9%, respectively), ground-glass attenuation (64.3% and κ = 0.24, respectively), and cysts/bullae (κ = 0.47 and κ = 0.44, respectively). Qualitative analysis of the HRCT findings of bronchiectasis and the resulting individual patient scores showed that there was an excellent correlation between the observers (intra class correlation coefficient of 0.85 and 0.81 for interobserver and intraobserver agreement, respectively). Conclusion: In the interpretation of HRCT findings of bronchiectasis, radiologist agreement appears to be fair. In our final analysis of the findings using the proposed score, we observed excellent interobserver and intraobserver agreement. (author)

  11. Percutaneous nephrolithotomy in pediatric patients: is computerized tomography a must?

    Science.gov (United States)

    Gedik, Abdullah; Tutus, Ali; Kayan, Devrim; Yılmaz, Yakup; Bircan, Kamuran

    2011-02-01

    The aim of this study was to retrospectively evaluate the results of pediatric percutaneous nephrolithotomy (PNL) cases, and discuss the results and necessity of non-contrast computerized tomography (CT) in these cases. In all, 48 pediatric patients who underwent PNL were retrospectively evaluated. Before PNL, either intravenous urography or CT was performed. In all patients, we evaluated the PNL time, scopy time with stone burden, and complications. During the PNL procedure, we switched to open surgery in two cases: in one because of renal pelvis perforation and in the other because of transcolonic access. In one patient who was scheduled to undergo PNL, we performed open surgery, primarily because we detected a retrorenal colon with CT. The stone burden in 45 patients who underwent PNL was 445 ± 225 mm(2), the PNL time was 51 ± 23 min, and the scopy time was 6.1 ± 2.7 min. We removed nephrostomy tubes 1-4 days after the procedure. In two patients, 24 h after removal of nephrostomy tubes, we inserted double J stents because of prolonged urine extravasation from the tract. In all, 34 of the 45 patients were stone-free, 5 patients had clinically insignificant stone fragments, and 6 patients had residual stones. PNL is a safe and effective method in the treatment of pediatric patients with kidney stones. Clinical experience is the most important factor in obtaining stone-free results. CT should be performed in all pediatric patients in order to prevent colon perforation.

  12. Low osmolar (non-ionic) contrast media versus high osmolar (ionic) contrast media in intravenous urography and enhanced computerized tomography: a cost-effectiveness analysis.

    Science.gov (United States)

    Wangsuphachart, S

    1991-12-01

    The cost-effectiveness of three alternative policies for the use of intravenous contrast media for urography and enhanced computerized tomography (CT) are analyzed. Alternative #1 is to use high osmolar contrast media (HOCM) in all patients, the historical policy. Alternative #2 is to replace it with low osmolar contrast media (LOCM) in all patients. Alternative #3 is to use LOCM only in the high risk patients. Data on the 6,242 patients who underwent intravenous urography and enhanced CT at the Department of Radiology, Chulalongkorn Hospital in 1989 were used. Both societal and hospital viewpoints were analyzed. The incremental cost-effectiveness (ICE) between #2 and #1 was 26,739 Baht (US$1,070) per healthy day saved (HDS), while the ICE between #3 and #1 was 12,057 Baht (US$482) per HDS. For fatal cases only, ICE between #2 and #1 was 35,111 Baht (US$1,404) per HDS, while the ICE between #3 and #1 was 18,266 Baht (US$731) per HDS. The incremental cost (IC) per patient was 2,341 Baht (US$94) and 681 Baht (US$27) respectively. For the hospital viewpoint the ICE between #2 and #1 was 13,744 (US$550) and between #3 and #1 was 6,127 Baht (US$245) per HDS. The IC per patient was 1,203 Baht (US$48) and 346 Baht (US$14), respectively. From the sensitivity analysis, #3 should be used if the LOCM price is reduced more than 75% (equal to 626 Baht or less) and more than 80% of the patients are able to pay for the contrast media.

  13. Nonoperative treatment of splenic trauma: usefulness of computed tomography

    International Nuclear Information System (INIS)

    Resende, Vivian; Tavares Junior, Wilson Campos; Vieira, Jose Nelson Mendes; Drumond, Domingos Andre Fernandes

    2005-01-01

    Objective: to report the results of use of conservative treatment in patients with splenic trauma and to emphasize the usefulness of computed tomography in these cases. Material and method: sixty-nine cases of pediatric patients with blunt abdominal trauma seen from from January 2001 to June 2004 at the level I trauma center were retrospectively studied. Forty-four of these patients were submitted to nonoperative treatment and the clinical follow-up was performed by computerized tomography. All patients had been diagnosed with splenic injury by computerized tomography.Results: the causes of the injuries were motor vehicle accident in 12 (27.2%) patients, bicycle accident in nine (20.4%) patients, and falls in 23 (52.2%) patients. Two (3.7%) patients died from associated injuries. The mean duration of hospital stay was six days. The mean age of the patients was nine years. Conclusion: conservative treatment for blunt splenic trauma is performed with the aim of reducing costs and risks for the patients, and computerized tomography should be routinely used. No posterior complications were observed in this approach. (author)

  14. Comparison of micro-computerized tomography and cone-beam computerized tomography in the detection of accessory canals in primary molars

    OpenAIRE

    Acar, Buket; Kamburo?lu, K?van?; Tatar, ?lkan; Ar?kan, Volkan; ?elik, Hakan Hamdi; Y?ksel, Selcen; ?zen, Tuncer

    2015-01-01

    Purpose This study was performed to compare the accuracy of micro-computed tomography (CT) and cone-beam computed tomography (CBCT) in detecting accessory canals in primary molars. Materials and Methods Forty-one extracted human primary first and second molars were embedded in wax blocks and scanned using micro-CT and CBCT. After the images were taken, the samples were processed using a clearing technique and examined under a stereomicroscope in order to establish the gold standard for this s...

  15. High-resolution computed tomography of the temporal bone. Part 2.: pathology

    International Nuclear Information System (INIS)

    Grzegorzewski, M.; Boron, Z.; Burzynska-Makuch, M.

    1995-01-01

    Selected cases of the temporal bone pathology on high resolution CT were demonstrated. Transverse and coronal sections of the cases were selected from 68 patients with various otological diseases. (author)

  16. Tomography methods for diagnostic examination of cerebrovascular disease: a comparative evaluation of SPECT, PET and MR/CT findings

    International Nuclear Information System (INIS)

    Reiche, W.; Kaiser, H.J.; Weiller, C.; Altehoefer, C.; Buell, U.; Isensee, C.

    1991-01-01

    Single Photon Emissions Computerized Tomography (SPECT), Positron Emissions Tomography (PET), Magnetic Resonance Tomography (MR), and Transmission Computerized Tomography (CT) complement each other and lead to a consideration of the cerebrovascular disease under patho-physiological aspects. Indications for the combined application of functionally oriented (SPECT/PET) and morphologically oriented (CT/MR) examination methods with cerebrovascular disease are presented. (orig./MG) [de

  17. High resolution 3D laboratory x-ray tomography data of femora from young, 1–14 day old C57BL/6 mice

    Directory of Open Access Journals (Sweden)

    Emely L. Bortel

    2015-09-01

    Full Text Available This data article contains high resolution (1.2 µm effective pixel size lab-based micro-computed tomography (µCT reconstructed volume data of the femoral mid-shafts from young C57BL/6 mice. This data formed the basis for the analyses of bone structural development in healthy mice, including closed and open porosity as reported in Bortel et al. [1]. The data reveals changes seen in bone material and porosity distribution observed when mouse bones transform from porous scaffolds into solid structures during normal organogenesis.

  18. Resting state rCBF mapping with single-photon emission tomography and positron emission tomography: magnitude and origin of differences

    Energy Technology Data Exchange (ETDEWEB)

    Jonsson, C.; Kimiaei, S.; Larsson, S.A. [Section of Nuclear Medicine, Department of Hospital Physics, Karolinska Hospital and Department of Medical Radiation Physics, Stockholm University, Stockholm (Sweden); Pagani, M. [Institute of Experimental Medicine, CNR, Rome (Italy); Ingvar, M. [Section of Cognitive Neurophysiology, Karolinska Hospital, Stockholm (Sweden); Thurfjell, L. [Center of Image Analysis, Uppsala University, Uppsala (Sweden); Jacobsson, H. [Department of Diagnostic Radiology, Karolinska Hospital, Stockholm (Sweden)

    1998-02-01

    Single-photon emission tomography (SPET), using technetium-99m hexamethylpropylene amine oxime, and positron emission tomography (PET), using oxygen-15 butanol were compared in six healthy male volunteers with regard to the mapping of resting state regional cerebral blood flow (rCBF). A computerized brain atlas was utilized for 3D regional analyses and comparison of 64 selected and normalized volumes of interest (VOIs). The normalized mean rCBF values in SPET, as compared to PET, were higher in most of the Brodmann areas in the frontal and parietal lobes (4.8% and 8.7% respectively). The average differences were small in the temporal (2.3%) and occipital (1.1%) lobes. PET values were clearly higher in small VOIs like the thalamus (12.3%), hippocampus (12.3%) and basal ganglia (9.9%). A resolution phantom study showed that the in-plane SPET/PET system resolution was 11.0/7.5 mm. In conclusion, SPET and PET data demonstrated a fairly good agreement despite the superior spatial resolution of PET. The differences between SPET and PET rCBF are mainly due to physiological and physical factors, the data processing, normalization and co-registration methods. In order to further improve mapping of rCBF with SPET it is imperative not only to improve the spatial resolution but also to apply accurate correction techniques for scatter, attenuation and non-linear extraction. (orig.) With 6 figs., 3 tabs., 23 refs.

  19. Microstructural abnormalities in MEWDS demonstrated by ultrahigh resolution optical coherence tomography.

    Science.gov (United States)

    Nguyen, My Hanh T; Witkin, Andre J; Reichel, Elias; Ko, Tony H; Fujimoto, James G; Schuman, Joel S; Duker, Jay S

    2007-01-01

    Histopathological studies of acute multiple evanescent white dot syndrome (MEWDS) have not been reported because of the transient and benign nature of the disease. Ultrahigh resolution optical coherence tomography (UHR-OCT), capable of high resolution in vivo imaging, offers a unique opportunity to visualize retinal microstructure in the disease. UHR-OCT images of the maculae of five patients with MEWDS were obtained and analyzed. Diagnosis was based on clinical presentation, examination, visual field testing, and angiography. UHR-OCT revealed disturbances in the photoreceptor inner/outer segment junction (IS/OS) in each of the five patients (six eyes) with MEWDS. In addition, thinning of the outer nuclear layer was seen in the case of recurrent MEWDS, suggesting that repeated episodes of MEWDS may result in photoreceptor atrophy. Subtle disruptions of the photoreceptor IS/OS are demonstrated in all eyes affected by MEWDS. UHR-OCT may be a useful adjunct to diagnosis and monitoring of MEWDS.

  20. Epiploic appendicitis and omental infarction. Findings in the ultrasonography and computerized tomography; Apendicitis epiploica e infarto omental. Hallazgos en ecografia y tomografia computarizada

    Energy Technology Data Exchange (ETDEWEB)

    Migule, A.; Ripolles, T.; Martinez, M. J.; Morote, V.; Ruiz, A. [Hospital Universitario Dr. Peset. Valencia (Spain)

    2001-07-01

    Describe the findings in the ultrasonography and computerized tomography (CT) of the omental infarction and epiploic appendicitis. The clinical and radiological findings of the patients diagnosed in our hospital with epiploic appendicitis or omental infarctions between August 1994 and March 2001 were assessed retrospectively. We found a high incidence (42 cases) of these two diseases: 30 patients with diagnosis of epiploic appendicitis and 12 with the diagnosis of omental infarction. Four patients were treated surgically, while the remaining 38 were conservatively, without posterior complications. The ultrasonography and CT images is characteristics. making it possible to make a diagnosis of epiploic appendicitis or omental infarction with certainty. It is not necessary to make a differential diagnosis between the two entities because their prognosis and treatment are similar. Their incidence is much more frequent than that previously published. (Author) 19 refs.

  1. Isotropic-resolution linear-array-based photoacoustic computed tomography through inverse Radon transform

    Science.gov (United States)

    Li, Guo; Xia, Jun; Li, Lei; Wang, Lidai; Wang, Lihong V.

    2015-03-01

    Linear transducer arrays are readily available for ultrasonic detection in photoacoustic computed tomography. They offer low cost, hand-held convenience, and conventional ultrasonic imaging. However, the elevational resolution of linear transducer arrays, which is usually determined by the weak focus of the cylindrical acoustic lens, is about one order of magnitude worse than the in-plane axial and lateral spatial resolutions. Therefore, conventional linear scanning along the elevational direction cannot provide high-quality three-dimensional photoacoustic images due to the anisotropic spatial resolutions. Here we propose an innovative method to achieve isotropic resolutions for three-dimensional photoacoustic images through combined linear and rotational scanning. In each scan step, we first elevationally scan the linear transducer array, and then rotate the linear transducer array along its center in small steps, and scan again until 180 degrees have been covered. To reconstruct isotropic three-dimensional images from the multiple-directional scanning dataset, we use the standard inverse Radon transform originating from X-ray CT. We acquired a three-dimensional microsphere phantom image through the inverse Radon transform method and compared it with a single-elevational-scan three-dimensional image. The comparison shows that our method improves the elevational resolution by up to one order of magnitude, approaching the in-plane lateral-direction resolution. In vivo rat images were also acquired.

  2. Limiting liability via high resolution image processing

    Energy Technology Data Exchange (ETDEWEB)

    Greenwade, L.E.; Overlin, T.K.

    1996-12-31

    The utilization of high resolution image processing allows forensic analysts and visualization scientists to assist detectives by enhancing field photographs, and by providing the tools and training to increase the quality and usability of field photos. Through the use of digitized photographs and computerized enhancement software, field evidence can be obtained and processed as `evidence ready`, even in poor lighting and shadowed conditions or darkened rooms. These images, which are most often unusable when taken with standard camera equipment, can be shot in the worst of photographic condition and be processed as usable evidence. Visualization scientists have taken the use of digital photographic image processing and moved the process of crime scene photos into the technology age. The use of high resolution technology will assist law enforcement in making better use of crime scene photography and positive identification of prints. Valuable court room and investigation time can be saved and better served by this accurate, performance based process. Inconclusive evidence does not lead to convictions. Enhancement of the photographic capability helps solve one major problem with crime scene photos, that if taken with standard equipment and without the benefit of enhancement software would be inconclusive, thus allowing guilty parties to be set free due to lack of evidence.

  3. 3D high-resolution radar imaging of small body interiors

    Science.gov (United States)

    Sava, Paul; Asphaug, Erik

    2017-10-01

    Answering fundamental questions about the origin and evolution of small planetary bodies hinges on our ability to image their interior structure in detail and at high resolution (Asphaug, 2009). We often infer internal structure from surface observations, e.g. that comet 67P/Churyumov-Gerasimenko is a primordial agglomeration of cometesimals (Massironi et al., 2015). However, the interior structure is not easily accessible without systematic imaging using, e.g., radar transmission and reflection data, as suggested by the CONSERT experiment on Rosetta. Interior imaging depends on observations from multiple viewpoints, as in medical tomography.We discuss radar imaging using methodology adapted from terrestrial exploration seismology (Sava et al., 2015). We primarily focus on full wavefield methods that facilitate high quality imaging of small body interiors characterized by complex structure and large contrasts of physical properties. We consider the case of a monostatic system (co-located transmitters and receivers) operated at two frequency bands, centered around 5 and 15 MHz, from a spacecraft in slow polar orbit around a spinning comet nucleus. Assuming that the spin period is significantly (e.g. 5x) faster than the orbital period, this configuration allows repeated views from multiple directions (Safaeinili et al., 2002)Using realistic numerical experiments, we argue that (1) the comet/asteroid imaging problem is intrinsically 3D and conventional SAR methodology does not satisfy imaging, sampling and resolution requirements; (2) imaging at different frequency bands can provide information about internal surfaces (through migration) and internal volumes (through tomography); (3) interior imaging can be accomplished progressively as data are being acquired through successive orbits around the studied object; (4) imaging resolution can go beyond the apparent radar frequency band by deconvolution of the point-spread-function characterizing the imaging system; and (5

  4. Theoretical limit of spatial resolution in diffuse optical tomography using a perturbation model

    International Nuclear Information System (INIS)

    Konovalov, A B; Vlasov, V V

    2014-01-01

    We have assessed the limit of spatial resolution of timedomain diffuse optical tomography (DOT) based on a perturbation reconstruction model. From the viewpoint of the structure reconstruction accuracy, three different approaches to solving the inverse DOT problem are compared. The first approach involves reconstruction of diffuse tomograms from straight lines, the second – from average curvilinear trajectories of photons and the third – from total banana-shaped distributions of photon trajectories. In order to obtain estimates of resolution, we have derived analytical expressions for the point spread function and modulation transfer function, as well as have performed a numerical experiment on reconstruction of rectangular scattering objects with circular absorbing inhomogeneities. It is shown that in passing from reconstruction from straight lines to reconstruction using distributions of photon trajectories we can improve resolution by almost an order of magnitude and exceed the accuracy of reconstruction of multi-step algorithms used in DOT. (optical tomography)

  5. Near-Infrared Diffuse Optical Tomography

    Directory of Open Access Journals (Sweden)

    A. H. Hielscher

    2002-01-01

    Full Text Available Diffuse optical tomography (DOT is emerging as a viable new biomedical imaging modality. Using near-infrared (NIR light, this technique probes absorption as well as scattering properties of biological tissues. First commercial instruments are now available that allow users to obtain cross-sectional and volumetric views of various body parts. Currently, the main applications are brain, breast, limb, joint, and fluorescence/bioluminescence imaging. Although the spatial resolution is limited when compared with other imaging modalities, such as magnetic resonance imaging (MRI or X-ray computerized tomography (CT, DOT provides access to a variety of physiological parameters that otherwise are not accessible, including sub-second imaging of hemodynamics and other fast-changing processes. Furthermore, DOT can be realized in compact, portable instrumentation that allows for bedside monitoring at relatively low cost. In this paper, we present an overview of current state-of-the -art technology, including hardware and image-reconstruction algorithms, and focus on applications in brain and joint imaging. In addition, we present recent results of work on optical tomographic imaging in small animals.

  6. Comparison of high resolution computed tomography and pulmonary function tests in diagnosis of mild emphysema

    International Nuclear Information System (INIS)

    Kuwano, Kazuyoshi; Matsuba, Kenichi; Ikeda, Togo

    1989-01-01

    To assess the ability of high resolution CT scan and pulmonary function tests in detecting and grading mild emphysema, we correlated the high resolution CT scan and pulmonary function tests with the pathologic grade of emphysema and the destructive index of lung specimens from 42 patients undergoing thoracotomy for solitary pulmonary nodules. Using the high resolution CT scan, we could identify the pathologic grade of mild and moderate emphysema. By measuring diffusing capacity per unit alveolar gas volume (DLco/VA), it seemed to be possible to detect the mildest degree of alveolar destruction assessed by the destructive index, which was not detected by high resolution CT scan. The reason for these results seemed to be that we assessed the severity of emphysema by detecting the air space enlargement on high resolution CT scan images caused by the destruction of alveolar walls, which were detectable by measuring DLco/VA. We conclude that it is possible to detect mild emphysema using the combination of high resolution CT scan and pulmomary function tests. (author)

  7. Computerized tomography in diagnosis of mammary gland cancer

    International Nuclear Information System (INIS)

    Ternovoj, S.K.; Shishmareva, N.F.

    1987-01-01

    A total of 103 women with suspected malignant breast tumors were examined using combined methods including computed tomography (CT). Cancer was diagnosed in 81 patients benign breast tumors in 22. The authors obtained data concerning CT superiority in the diagnosis of tumors localized in the retromammary space, as well as infinitrative-edematous forms of cancer and breast cancer recurrences. A high reliability of the method in the detection of metastatic involvement of the axillary lymph nodes made it possible to give up transmission axillography

  8. High-resolution optical coherence tomography using broadband light source with strain-controlled InAs/GaAs quantum dots

    Energy Technology Data Exchange (ETDEWEB)

    Tsubaki, Ippei; Harada, Yukihiro; Kita, Takashi [Department of Electrical and Electronic Engineering, Graduate School of Engineering, Kobe University, 1-1 Rokkodai, Nada, Kobe 657-8501 (Japan)

    2012-12-15

    Recently, there has been an increasing interest in broadband light sources to develop a biomolecular imaging technique called optical coherence tomography (OCT). We fabricated superluminescent diodes (SLDs) using three kinds of quantum dot (QD) layers with different emission wavelength in the active region. The emission wavelength was controlled by reducing the strain in QDs by using In{sub 0.1}Ga{sub 0.9}As strain-reducing layer. The SLD device showed a broad electroluminescence spectrum with the center wavelength of 1104 nm and the spectral linewidth of 122 nm at the injection of 40 mA, which corresponds to the theoretical axial resolution of 4.4 {mu}m. To estimate the actual resolution of the OCT system using fabricated SLD, we measured the interference signal in the Michelson interferometer. An axial resolution of 5.4 {mu}m, which is close to the theoretical limit, was obtained (copyright 2012 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  9. A tomografia computadorizada de alta resolução na avaliação da toxicidade pulmonar por amiodarona High-resolution computed tomography of amiodarone pulmonary toxicity

    Directory of Open Access Journals (Sweden)

    Daniela Peixoto Consídera

    2006-04-01

    Full Text Available OBJETIVO: Avaliar as principais alterações identificadas na tomografia computadorizada de alta resolução do tórax em pacientes com toxicidade pulmonar pela amiodarona. MATERIAIS E MÉTODOS: Foram avaliadas dez tomografias computadorizadas de alta resolução de tórax de pacientes com pneumonite pela amiodarona, seis desses pacientes do sexo masculino e quatro do sexo feminino, com idade média de 73,5 anos. RESULTADOS: Os achados tomográficos mais relevantes foram opacidades lineares ou reticulares em seis casos (60%, pequenos nódulos com densidade elevada em seis casos (60%, consolidações densas em três casos (30% e aumento da densidade do parênquima hepático em cinco de oito casos em que havia estudo tomográfico do abdome superior (62,5%. CONCLUSÃO: A tomografia computadorizada de alta resolução é um exame importante na avaliação de pacientes com toxicidade pulmonar pela amiodarona, devendo ser realizada sempre que houver suspeita deste diagnóstico. O achado de espessamento de septos interlobulares associado a lesões com aumento de densidade é altamente sugestivo deste diagnóstico.OBJECTIVE: To evaluate the main findings of chest high-resolution computed tomography in patients with amiodarone pulmonary toxicity. MATERIALS AND METHODS: Ten patients - six male and four female, average age of 73.5 years - with amiodarone-induced pneumonitis have undergone chest high-resolution computed tomography. RESULTS: The most relevant tomographic findings were linear or reticular opacities in six cases (60%, small high density nodules in six cases (60%, dense consolidations in three cases (30% and increased density in the hepatic parenchyma in five of eight cases in which there was a superior abdomen CT scan (62.5%. CONCLUSION: The high-resolution computed tomography is a valuable non-invasive test for evaluating patients with amiodarone pulmonary toxicity and should always be performed when one suspects of the presence of this

  10. High resolution aquifer characterization using crosshole GPR full-waveform tomography

    Science.gov (United States)

    Gueting, N.; Vienken, T.; Klotzsche, A.; Van Der Kruk, J.; Vanderborght, J.; Caers, J.; Vereecken, H.; Englert, A.

    2016-12-01

    Limited knowledge about the spatial distribution of aquifer properties typically constrains our ability to predict subsurface flow and transport. Here, we investigate the value of using high resolution full-waveform inversion of cross-borehole ground penetrating radar (GPR) data for aquifer characterization. By stitching together GPR tomograms from multiple adjacent crosshole planes, we are able to image, with a decimeter scale resolution, the dielectric permittivity and electrical conductivity of an alluvial aquifer along cross-sections of 50 m length and 10 m depth. A logistic regression model is employed to predict the spatial distribution of lithological facies on the basis of the GPR results. Vertical profiles of porosity and hydraulic conductivity from direct-push, flowmeter and grain size data suggest that the GPR predicted facies classification is meaningful with regard to porosity and hydraulic conductivity, even though the distributions of individual facies show some overlap and the absolute hydraulic conductivities from the different methods (direct-push, flowmeter, grain size) differ up to approximately one order of magnitude. Comparison of the GPR predicted facies architecture with tracer test data suggests that the plume splitting observed in a tracer experiment was caused by a hydraulically low-conductive sand layer with a thickness of only a few decimeters. Because this sand layer is identified by GPR full-waveform inversion but not by conventional GPR ray-based inversion we conclude that the improvement in spatial resolution due to full-waveform inversion is crucial to detect small-scale aquifer structures that are highly relevant for solute transport.

  11. Development of novel emission tomography system

    Science.gov (United States)

    Fu, Geng

    In recent years, small animals, such as mice and rats, have been widely used as subjects of study in biomedical research while molecular biology and imaging techniques open new opportunities to investigate disease model. With the help of medical imaging techniques, researchers can investigate underlying mechanisms inside the small animal, which are useful for both early diagnosis and treatment monitoring. Based on tracer principle single photon emission computed tomography (SPECT) has increased popularity in small animal imaging due to its higher spatial resolution and variety of single-photon emitting radionuclides. Since the image quality strongly depends on the detector properties, both scintillation and semiconductor detectors are under active investigation for high resolution X-ray and gamma ray photon detection. The desired detector properties include high intrinsic spatial resolution, high energy resolution, and high detection efficiency. In this thesis study, we have made extensive efforts to develop novel emission tomography system, and evaluate the use of both semiconductor and ultra-high resolution scintillation detectors for small animal imaging. This thesis work includes the following three areas. Firstly, we have developed a novel energy-resolved photon counting (ERPC) detector. With the benefits of high energy resolution, high spatial resolution, flexible detection area, and a wide dynamic range of 27--200keV, ERPC detector is well-suited for small animal SPECT applications. For prototype ERPC detector excellent imaging (˜350microm) and spectroscopic performance (4keV Co-57 122keV) has been demonstrated in preliminary study. Secondly, to further improve spatial resolution to hundred-micron level, an ultra-high resolution Intensified EMCCD (I-EMCCD) detector has been designed and evaluated. This detector consists of the newly developed electron multiplying CCD (EMCCD) sensor, columnar CsI(Tl) scintillator, and an electrostatic de-magnifier (DM) tube

  12. Imaging tissues for biomedical research using the high-resolution micro-tomography system nanotom® m

    Science.gov (United States)

    Deyhle, Hans; Schulz, Georg; Khimchenko, Anna; Bikis, Christos; Hieber, Simone E.; Jaquiery, Claude; Kunz, Christoph; Müller-Gerbl, Magdalena; Höchel, Sebastian; Saxer, Till; Stalder, Anja K.; Ilgenstein, Bernd; Beckmann, Felix; Thalmann, Peter; Buscema, Marzia; Rohr, Nadja; Holme, Margaret N.; Müller, Bert

    2016-10-01

    Micro computed tomography (mCT) is well established in virtually all fields of biomedical research, allowing for the non-destructive volumetric visualization of tissue morphology. A variety of specimens can be investigated, ranging from soft to hard tissue to engineered structures like scaffolds. Similarly, the size of the objects of interest ranges from a fraction of a millimeter to several tens of centimeters. While synchrotron radiation-based μCT still offers unrivaled data quality, the ever-improving technology of cathodic tube-based machines offers a valuable and more accessible alternative. The Biomaterials Science Center of the University of Basel operates a nanotomOR m (phoenix|x-ray, GE Sensing and Inspection Technologies GmbH, Wunstorf, Germany), with a 180 kV source and a minimal spot size of about 0.9 μm. Through the adjustable focus-specimen and focus-detector distances, the effective pixel size can be adjusted from below 500 nm to about 80 μm. On the high-resolution side, it is for example possible to visualize the tubular network in sub-millimeter thin dentin specimens. It is then possible to locally extract parameters such as tubule diameter, density, or alignment, giving information on cell movements during tooth formation. On the other side, with a horizontal shift of the 3,072 pixels x 2,400 pixels detector, specimens up to 35 cm in diameter can be scanned. It is possible, for example, to scan an entire human knee, albeit with inferior resolution. Lab source μCT machines are thus a powerful and flexible tool for the advancement of biomedical research, and a valuable and more accessible alternative to synchrotron radiation facilities.

  13. Changes in bone macro- and microstructure in diabetic obese mice revealed by high resolution microfocus X-ray computed tomography

    Science.gov (United States)

    Kerckhofs, G.; Durand, M.; Vangoitsenhoven, R.; Marin, C.; van der Schueren, B.; Carmeliet, G.; Luyten, F. P.; Geris, L.; Vandamme, K.

    2016-10-01

    High resolution microfocus X-ray computed tomography (HR-microCT) was employed to characterize the structural alterations of the cortical and trabecular bone in a mouse model of obesity-driven type 2 diabetes (T2DM). C57Bl/6J mice were randomly assigned for 14 weeks to either a control diet-fed (CTRL) or a high fat diet (HFD)-fed group developing obesity, hyperglycaemia and insulin resistance. The HFD group showed an increased trabecular thickness and a decreased trabecular number compared to CTRL animals. Midshaft tibia intracortical porosity was assessed at two spatial image resolutions. At 2 μm scale, no change was observed in the intracortical structure. At 1 μm scale, a decrease in the cortical vascular porosity of the HFD bone was evidenced. The study of a group of 8 week old animals corresponding to animals at the start of the diet challenge revealed that the decreased vascular porosity was T2DM-dependant and not related to the ageing process. Our results offer an unprecedented ultra-characterization of the T2DM compromised skeletal micro-architecture and highlight an unrevealed T2DM-related decrease in the cortical vascular porosity, potentially affecting the bone health and fragility. Additionally, it provides some insights into the technical challenge facing the assessment of the rodent bone structure using HR-microCT imaging.

  14. Changes in bone macro- and microstructure in diabetic obese mice revealed by high resolution microfocus X-ray computed tomography

    Science.gov (United States)

    Kerckhofs, G.; Durand, M.; Vangoitsenhoven, R.; Marin, C.; Van der Schueren, B.; Carmeliet, G.; Luyten, F. P.; Geris, L.; Vandamme, K.

    2016-01-01

    High resolution microfocus X-ray computed tomography (HR-microCT) was employed to characterize the structural alterations of the cortical and trabecular bone in a mouse model of obesity-driven type 2 diabetes (T2DM). C57Bl/6J mice were randomly assigned for 14 weeks to either a control diet-fed (CTRL) or a high fat diet (HFD)-fed group developing obesity, hyperglycaemia and insulin resistance. The HFD group showed an increased trabecular thickness and a decreased trabecular number compared to CTRL animals. Midshaft tibia intracortical porosity was assessed at two spatial image resolutions. At 2 μm scale, no change was observed in the intracortical structure. At 1 μm scale, a decrease in the cortical vascular porosity of the HFD bone was evidenced. The study of a group of 8 week old animals corresponding to animals at the start of the diet challenge revealed that the decreased vascular porosity was T2DM-dependant and not related to the ageing process. Our results offer an unprecedented ultra-characterization of the T2DM compromised skeletal micro-architecture and highlight an unrevealed T2DM-related decrease in the cortical vascular porosity, potentially affecting the bone health and fragility. Additionally, it provides some insights into the technical challenge facing the assessment of the rodent bone structure using HR-microCT imaging. PMID:27759061

  15. Clinical value of computerized tomography scanning in severe head injury

    International Nuclear Information System (INIS)

    Kobayashi, Shiro; Yano, Masami; Otsuka, Toshibumi; Nakazawa, Shozo

    1982-01-01

    Serial computerized tomography (SCT) was performed on 138 patients suffering from severe head injuries (8 or less on the Glasgow Coma Scale). Standard practice called for scans to be done upon admission (within hours of the injury), and after 1, 3, 7 days and 1 month. Subsequent CT's depended on the patient's condition. Clinical results at the time of discharge were graded according to the Glasgow Outcome Scale. Patients who died, were in a persistent vegetative state, or were severely disabled were considered to have a ''bad outcome''. On the other hand, patients who were somewhat disabled or made good recoveries were considered to have a ''good outcome''. During the serial CT scan, there were new findings (not visualized on the initial CT but appearing on subsequent ones) in 91 of the 138 patients. These new findings were classified as follows; 1) decreased density collection in the subdural space (DDC), 2) ventricular dilation (VD), 3) intracerebral hematoma (ICH), 4) intraventricular hemorrhage (IVH), 5) extracerebral hematoma (ECH), 6) edema (E), 7) infarction (I). We defined ICH, IVH, ECH, E and I as new lesions. Of the 60 patients with new lesions 12 had good outcomes and 48 had poor outcomes. There were 78 patients who did not have any new lesions, 60 with good outcomes and 18 with poor outcomes. A significant correlation was found between good outcomes and the absence of new lesions, and between bad outcomes and the development of new lesions (p 2 = 44.038). We conclude that SCT can help predict the outcome with severe head injury patients and may be very important in their examination and care. (J.P.N.)

  16. Proposal for dose measurement in the crystalline lens and thyroid in computerized tomography of paranasal sinuses

    International Nuclear Information System (INIS)

    Mello, Ana Caroline; Machado Neto, Vicente

    2014-01-01

    With the evolution of diagnostic imaging equipment, a computerized tomography (CT) has become one of the most used tests to assess pathologies affecting the paranasal sinuses. This work aims at presenting a method of obtaining measurements of dose in the eye lenses and thyroid, from the execution of CT of the paranasal sinuses protocol. Experimental procedure will be used in an object simulator (phantom) head and neck made with accessible materials and thermoluminescent dosimeters (TLDs) of LiF: Mg,Ti for the absorbed dose in the regions of interest, when exposed to radiation in a CT scanner 16 channels. After the dosimetric evaluation with phantom use, this methodology will be applied in vivo, or in patients with medical request for the examination and approval by the Ethics Committee. Thus, at the end of this survey protocols and actions aimed at reducing the absorbed dose in the eye lenses and thyroid without impairing the diagnostic image quality can be proposed. (author)

  17. Clinical evaluation of 99mTc-CPI myocardial perfusion single photon emission computerized tomography in the diagnosis of coronary heart disease

    International Nuclear Information System (INIS)

    Peng Changping

    1991-01-01

    Two normal subjects, 5 patients with old myocardial infarction (OMI) and 4 patients with angina pectoris were examined by rest single photon emission computerized tomography revealed that the right ventricular was not imaged, the left ventricular was well exposed in the normal subjects. All the 9 patients had defects in the left ventricle. comparison of SPECT with 99m Tc-CPI with selective coronary arteriography (SCA), echocardiography (UCG), dynamic electrocardiography (DCG) and electrocardiographic (ECG)-exercise test in the diagnosis of myocardial ischemia or necrosis has demonstrated the former to be more significantly sensitive than the latter four. Good agreement between SPECT and SCA has been confirmed

  18. Preclinical evaluation and intraoperative human retinal imaging with a high-resolution microscope-integrated spectral domain optical coherence tomography device.

    Science.gov (United States)

    Hahn, Paul; Migacz, Justin; O'Donnell, Rachelle; Day, Shelley; Lee, Annie; Lin, Phoebe; Vann, Robin; Kuo, Anthony; Fekrat, Sharon; Mruthyunjaya, Prithvi; Postel, Eric A; Izatt, Joseph A; Toth, Cynthia A

    2013-01-01

    The authors have recently developed a high-resolution microscope-integrated spectral domain optical coherence tomography (MIOCT) device designed to enable OCT acquisition simultaneous with surgical maneuvers. The purpose of this report is to describe translation of this device from preclinical testing into human intraoperative imaging. Before human imaging, surgical conditions were fully simulated for extensive preclinical MIOCT evaluation in a custom model eye system. Microscope-integrated spectral domain OCT images were then acquired in normal human volunteers and during vitreoretinal surgery in patients who consented to participate in a prospective institutional review board-approved study. Microscope-integrated spectral domain OCT images were obtained before and at pauses in surgical maneuvers and were compared based on predetermined diagnostic criteria to images obtained with a high-resolution spectral domain research handheld OCT system (HHOCT; Bioptigen, Inc) at the same time point. Cohorts of five consecutive patients were imaged. Successful end points were predefined, including ≥80% correlation in identification of pathology between MIOCT and HHOCT in ≥80% of the patients. Microscope-integrated spectral domain OCT was favorably evaluated by study surgeons and scrub nurses, all of whom responded that they would consider participating in human intraoperative imaging trials. The preclinical evaluation identified significant improvements that were made before MIOCT use during human surgery. The MIOCT transition into clinical human research was smooth. Microscope-integrated spectral domain OCT imaging in normal human volunteers demonstrated high resolution comparable to tabletop scanners. In the operating room, after an initial learning curve, surgeons successfully acquired human macular MIOCT images before and after surgical maneuvers. Microscope-integrated spectral domain OCT imaging confirmed preoperative diagnoses, such as full-thickness macular hole

  19. Cerebral perfusion computerized tomography: influence of reference vessels, regions of interest and interobserver variability

    International Nuclear Information System (INIS)

    Soustiel, Jean F.; Mor, Nadav; Zaaroor, Menashe; Goldsher, Dorith

    2006-01-01

    There are still no standardized guidelines for perfusion computerized tomography (PCT) analysis. A total of 61 PCT studies were analyzed using either the anterior cerebral artery (ACA) or the middle cerebral artery (MCA) as the arterial reference, and the superior sagittal sinus (SSS) or the vein of Galen (VG) as the venous reference. The sizes of regions of interest (ROI) were investigated comparing PCT results obtained using a hemispheric ROI combined with vascular pixel elimination with those obtained using five smaller ROIs located over the cortex and basal ganglia. In addition, interobserver variations were explored using a standardized protocol. MCA-based measurements of cerebral blood flow (CBF) and blood volume (CBV) were in accordance with those obtained with the ACA except in 16 patients with ischemic stroke, in whom CBF was overestimated by the ipsilateral MCA. Venous maximal intensity was significantly lower with the VG when compared with the SSS, resulting in overestimation of CBF and CBV. However, in 13.3% of patients the VG ROI yielded higher maximal intensities than the SSS ROI. There was no difference in PCT results between hemispheric ROI and averaged separate ROI when vascular pixel elimination was used. Finally, interobserver variations were as high as 11% for CBF and 12% for CBV. The present results suggest that pathological rather than anatomical considerations should dictate the choice of the arterial ROI. For venous ROI, although SSS seems to be adequate in most instances, deep cerebral veins may occasionally generate higher maximal intensities and should therefore be selected. Importantly, significant user-dependency should be taken into account. (orig.)

  20. Exogenous lipoid pneumonia: high-resolution CT findings

    International Nuclear Information System (INIS)

    Lee, J.S.; Song, K.S.; Lim, T.H.; Im, J.G.; Seo, J.B.

    1999-01-01

    The aim of this study was to assess high-resolution computed tomography (HRCT) findings of exogenous lipoid pneumonia. High-resolution computed tomography was obtained in 25 patients with proven exogenous lipoid pneumonia resulting from aspiration of squalene (derived from shark liver oil). Diagnosis was based on biopsy (n = 9), bronchoalveolar lavage (n = 8), or sputum cytology and clinical findings (n = 8). The clinical history of taking squalene was confirmed in all patients. The CT findings were classified into three patterns: diffuse ground-glass opacity, consolidation, and interstitial abnormalities. Distribution of the abnormalities, duration of taking squalene, predisposing factors for aspiration, and route of administration were analyzed. Ten patients showed diffuse ground-glass opacity pattern. Seven of 10 patients had predisposing conditions such as unconsciousness, pharyngeal dysmotility, or motor disturbances, and 6 patients had a recent history of taking large amount of squalene through nasal route. Seven patients who had consolidation pattern had a history of taking squalene for several months and did not have any predisposing factor. All of the 5 patients who had a pattern of interstitial abnormalities had a history of taking squalene longer than 1 year and showed segmental distribution of interstitial thickening with interposing ground-glass opacities. Three patients simultaneously had two different patterns at different lobes of the lung. The HRCT findings of lipoid pneumonia are ground-glass opacities, consolidation, and interstitial abnormalities. These HRCT findings with appropriate inquiries could be useful for diagnosis of exogeneous lipoid pneumonia. (orig.)

  1. High-resolution in vivo imaging of the cross-sectional deformations of contracting embryonic heart loops using optical coherence tomography

    DEFF Research Database (Denmark)

    Männer, J.; Thrane, Lars; Norozi, K.

    2008-01-01

    The embryonic heart tube consists of an outer myocardial tube, a middle layer of cardiac jelly, and an inner endocardial tube. It is said that tubular hearts pump the blood by peristaltoid contractions. The traditional concept of cardiac peristalsis sees the cyclic deformations of pulsating heart...... tubes as concentric narrowing and widening of tubes of circular cross-section. We have visualized the cross-sectional deformations of contracting embryonic hearts in chick embryos (HH-stages 9-17) using real-time high-resolution optical coherence tomography. Cardiac contractions are detected from HH...... of the endocardial tube is the consequence of an uneven distribution of the cardiac jelly. Our data show that the cyclic deformations of pulsating embryonic heart tubes run other than originally thought. There is evidence that heart tubes of elliptic cross-section might pump blood with a higher mechanical efficiency...

  2. Determination of the initial energy in computerized tomography with proton beams; Determinacao da energia inicial em tomografia computadorizada com feixe de protons

    Energy Technology Data Exchange (ETDEWEB)

    Rocha, Rodrigo Luis da

    2007-07-01

    In earliest works devoted to proton computed tomography it was shown that the advantage of pCT image reconstruction appears when the energy is close to the Bragg peak region, since the proton passes the object. This effect provided by the Bragg peak makes the computerized tomography with protons possible. However, when decreasing the initial proton energy, with the increase of the irradiation dose, there are two effects that work simultaneously in opposite ways. First, the energy loss of a proton in an object becomes bigger at small initial energy. At the same time decreasing of the proton energy results in the increase of the energy straggling, requiring a larger number of protons. In this work the radiation dose dependence on the proton initial energy was studied using analytical formulas and computer simulations. The investigation determined that the radiation dose practically does not depend on the initial energy, except in the energy region very close to the minimum energy necessary to pass the object. (author)

  3. Computerized tomography in the diagnosis of mechanical jaundice

    International Nuclear Information System (INIS)

    Grushin, Yu.V.; Manasov, T.Zh.; Raskolenko, A.A.; Nazyrova, N.K.; Dzhumashev, E.Z.

    1987-01-01

    A total of 51 patients with suspected mechanical jaundice were examined using the 3rd generation computerized tomograph. A correct conclusion as to the level and mechanism of obstruction was made in 77% of cases. The most serious problems arose in analysis of extrahepatic biliary ducts. The dilatation of the biliary passages was not always combined with their obturation. In cases which were difficult for interpretation, additional information could be obtained by using thin tomographic layers, i.v. contrast enhancement, and retrograde endoscopic cholangiography

  4. High resolution electrical resistivity tomography of golf course greens irrigated with reclaimed wastewater: Hydrological approach

    Science.gov (United States)

    Tapias, Josefina C.; Lovera, Raúl; Himi, Mahjoub; Gallardo, Helena; Sendrós, Alexandre; Marguí, Eva; Queralt, Ignasi; Casas, Albert

    2014-05-01

    tomography is a non-invasive and cost-effective technique for high resolution characterizing the subsurface below golf course greens. The obtained models have provided detailed information on the lateral and vertical variability of each the subsurface and from an empirical correlation between the values of electrical resistivity and hydraulic permeability to assess the preferred areas of drainage that could pose in risk to the vulnerability of the underlying aquifers.

  5. Vascular channels in metacarpophalangeal joints : a comparative histologic and high-resolution imaging study

    NARCIS (Netherlands)

    Scharmga, A.; Keller, K.K.; Peters, M.; van Tubergen, A.; van den Bergh, J.P.W.; van Rietbergen, B.; Weijers, R.; Loeffen, D.; Hauge, E.M.; Geusens, P.P.M.M.

    2017-01-01

    We evaluated whether cortical interruptions classified as vascular channel (VC) on high-resolution peripheral quantitative computed tomography (HR-pQCT) could be confirmed by histology. We subsequently evaluated the image characteristics of histologically identified VCs on matched single and

  6. Fast iterative segmentation of high resolution medical images

    International Nuclear Information System (INIS)

    Hebert, T.J.

    1996-01-01

    Various applications in positron emission tomography (PET), single photon emission computed tomography (SPECT) and magnetic resonance imaging (MRI) require segmentation of 20 to 60 high resolution images of size 256x256 pixels in 3-9 seconds per image. This places particular constraints on the design of image segmentation algorithms. This paper examines the trade-offs in segmenting images based on fitting a density function to the pixel intensities using curve-fitting versus the maximum likelihood method. A quantized data representation is proposed and the EM algorithm for fitting a finite mixture density function to the quantized representation for an image is derived. A Monte Carlo evaluation of mean estimation error and classification error showed that the resulting quantized EM algorithm dramatically reduces the required computation time without loss of accuracy

  7. High-resolution surface wave tomography of the European crust and uppermost mantle from ambient seismic noise

    Science.gov (United States)

    Lu, Yang; Stehly, Laurent; Paul, Anne; AlpArray Working Group

    2018-05-01

    Taking advantage of the large number of seismic stations installed in Europe, in particular in the greater Alpine region with the AlpArray experiment, we derive a new high-resolution 3-D shear-wave velocity model of the European crust and uppermost mantle from ambient noise tomography. The correlation of up to four years of continuous vertical-component seismic recordings from 1293 broadband stations (10° W-35° E, 30° N-75° N) provides Rayleigh wave group velocity dispersion data in the period band 5-150 s at more than 0.8 million virtual source-receiver pairs. Two-dimensional Rayleigh wave group velocity maps are estimated using adaptive parameterization to accommodate the strong heterogeneity of path coverage. A probabilistic 3-D shear-wave velocity model, including probability densities for the depth of layer boundaries and S-wave velocity values, is obtained by non-linear Bayesian inversion. A weighted average of the probabilistic model is then used as starting model for the linear inversion step, providing the final Vs model. The resulting S-wave velocity model and Moho depth are validated by comparison with previous geophysical studies. Although surface-wave tomography is weakly sensitive to layer boundaries, vertical cross-sections through our Vs model and the associated probability of presence of interfaces display striking similarities with reference controlled-source (CSS) and receiver-function sections across the Alpine belt. Our model even provides new structural information such as a ˜8 km Moho jump along the CSS ECORS-CROP profile that was not imaged by reflection data due to poor penetration across a heterogeneous upper crust. Our probabilistic and final shear wave velocity models have the potential to become new reference models of the European crust, both for crustal structure probing and geophysical studies including waveform modeling or full waveform inversion.

  8. Simultaneous dual wavelength eye-tracked ultrahigh resolution retinal and choroidal optical coherence tomography

    DEFF Research Database (Denmark)

    Unterhuber, A.; Povaay, B.; Müller, André

    2013-01-01

    We demonstrate an optical coherence tomography device that simultaneously combines different novel ultrabroad bandwidth light sources centered in the 800 and 1060 nm regions, operating at 66 kHz depth scan rate, and a confocal laser scanning ophthalmoscope-based eye tracker to permit motion......-artifact-free, ultrahigh resolution and high contrast retinal and choroidal imaging. The two wavelengths of the device provide the complementary information needed for diagnosis of subtle retinal changes, while also increasing visibility of deeper-lying layers to image pathologies that include opaque media in the anterior...... eye segment or eyes with increased choroidal thickness....

  9. Established rheumatoid arthritis - new imaging modalities

    DEFF Research Database (Denmark)

    McQueen, Fiona M; Østergaard, Mikkel

    2007-01-01

    in real-time and facilitates diagnostic and therapeutic interventions such as joint aspiration and injection. Exciting experimental modalities are also being developed with the potential to provide not just morphological but functional imaging. Techniques such as positron emission tomography (PET......) and high-resolution computerized tomography. Erosions are very clearly depicted using these modalities and MRI also allows imaging of soft tissues with assessment of joint inflammation. High-resolution ultrasound is a convenient clinical technique for the assessment of erosions, synovitis and tenosynovitis...

  10. Imaging of cellular spread on a three-dimensional scaffold by means of a novel cell-labeling technique for high-resolution computed tomography.

    Science.gov (United States)

    Thimm, Benjamin W; Hofmann, Sandra; Schneider, Philipp; Carretta, Roberto; Müller, Ralph

    2012-03-01

    Computed tomography (CT) represents a truly three-dimensional (3D) imaging technique that can provide high-resolution images on the cellular level. Thus, one approach to detect single cells is X-ray absorption-based CT, where cells are labeled with a dense, opaque material providing the required contrast for CT imaging. Within the present work, a novel cell-labeling method has been developed showing the feasibility of labeling fixed cells with iron oxide (FeO) particles for subsequent CT imaging and quantitative morphometry. A biotin-streptavidin detection system was exploited to bind FeO particles to its target endothelial cells. The binding of the particles was predominantly close to the cell centers on 2D surfaces as shown by light microscopy, scanning electron microscopy, and CT. When cells were cultured on porous, 3D polyurethane surfaces, significantly more FeO particles were detected compared with surfaces without cells and FeO particle labeling using CT. Here, we report on the implementation and evaluation of a novel cell detection method based on high-resolution CT. This system has potential in cell tracking for 3D in vitro imaging in the future.

  11. Three-Dimensional Imaging and Numerical Reconstruction of Graphite/Epoxy Composite Microstructure Based on Ultra-High Resolution X-Ray Computed Tomography

    Science.gov (United States)

    Czabaj, M. W.; Riccio, M. L.; Whitacre, W. W.

    2014-01-01

    A combined experimental and computational study aimed at high-resolution 3D imaging, visualization, and numerical reconstruction of fiber-reinforced polymer microstructures at the fiber length scale is presented. To this end, a sample of graphite/epoxy composite was imaged at sub-micron resolution using a 3D X-ray computed tomography microscope. Next, a novel segmentation algorithm was developed, based on concepts adopted from computer vision and multi-target tracking, to detect and estimate, with high accuracy, the position of individual fibers in a volume of the imaged composite. In the current implementation, the segmentation algorithm was based on Global Nearest Neighbor data-association architecture, a Kalman filter estimator, and several novel algorithms for virtualfiber stitching, smoothing, and overlap removal. The segmentation algorithm was used on a sub-volume of the imaged composite, detecting 508 individual fibers. The segmentation data were qualitatively compared to the tomographic data, demonstrating high accuracy of the numerical reconstruction. Moreover, the data were used to quantify a) the relative distribution of individual-fiber cross sections within the imaged sub-volume, and b) the local fiber misorientation relative to the global fiber axis. Finally, the segmentation data were converted using commercially available finite element (FE) software to generate a detailed FE mesh of the composite volume. The methodology described herein demonstrates the feasibility of realizing an FE-based, virtual-testing framework for graphite/fiber composites at the constituent level.

  12. Attenuation Correction Strategies for Positron Emission Tomography/Computed Tomography and 4-Dimensional Positron Emission Tomography/Computed Tomography

    OpenAIRE

    Pan, Tinsu; Zaidi, Habib

    2013-01-01

    This article discusses attenuation correction strategies in positron emission tomography/computed tomography (PET/CT) and 4 dimensional PET/CT imaging. Average CT scan derived from averaging the high temporal resolution CT images is effective in improving the registration of the CT and the PET images and quantification of the PET data. It underscores list mode data acquisition in 4 dimensional PET and introduces 4 dimensional CT popular in thoracic treatment planning to 4 dimensional PET/CT. ...

  13. Tuberculous otitis media: findings on high-resolution CT

    International Nuclear Information System (INIS)

    Lungenschmid, D.; Buchberger, W.; Schoen, G.; Schoepf, R.; Mihatsch, T.; Birbamer, G.; Wicke, K.

    1993-01-01

    We describe two cases of tuberculous otitis media studied with high-resolution computed tomography (CT). Findings included extensive soft tissue densities with fluid levels in the tympanic cavity, the antrum, the mastoid and petrous air cells. Multifocal bony erosions and reactive bone sclerosis were seen as well. CT proved valuable for planning therapy by accurately displaying the involvement of the various structures of the middle and inner ear. However, the specific nature of the disease could only be presumed. (orig.)

  14. Computerization of the safeguards analysis decision process

    International Nuclear Information System (INIS)

    Ehinger, M.H.

    1990-01-01

    This paper reports that safeguards regulations are evolving to meet new demands for timeliness and sensitivity in detecting the loss or unauthorized use of sensitive nuclear materials. The opportunities to meet new rules, particularly in bulk processing plants, involve developing techniques which use modern, computerized process control and information systems. Using these computerized systems in the safeguards analysis involves all the challenges of the man-machine interface experienced in the typical process control application and adds new dimensions to accuracy requirements, data analysis, and alarm resolution in the regulatory environment

  15. Indications for application of a high resolution coil in MR tomography. Indikationen zur Applikation einer Hochaufloesungsspule in der MR-Tomographie

    Energy Technology Data Exchange (ETDEWEB)

    Maeurer, J. (Strahlenklinik und Poliklinik, Klinikum Rudolf Virchow, Standort Wedding, Freie Univ. Berlin (Germany)); Requardt, H. (Siemens AG, Erlangen (Germany)); Mueller, F. (Strahlenklinik und Poliklinik, Klinikum Rudolf Virchow, Standort Wedding, Freie Univ. Berlin (Germany)); Steinkamp, H.J. (Strahlenklinik und Poliklinik, Klinikum Rudolf Virchow, Standort Wedding, Freie Univ. Berlin (Germany)); Hosten, N. (Strahlenklinik und Poliklinik, Klinikum Rudolf Virchow, Standort Wedding, Freie Univ. Berlin (Germany)); Langer, R. (Strahlenklinik und Poliklinik, Klinikum Rudolf Virchow, Standort Wedding, Freie Univ. Berlin (Germany)); Felix, R. (Strahlenklinik und Poliklinik, Klinikum Rudolf Virchow, Standort Wedding, Freie Univ. Berlin (Germany))

    1994-04-01

    This is the first study with high spatial resolution Magnetic Resonance Imaging (MRI), performed with a high resolution coil in a clinical whole-body system. Measurements were recorded with a slice thickness of 2 mm. A 256x256 matrix and a 2.5 cm field of view were used resulting in a pixel size of 1.01 mm[sup 2]. MR images of the skin, hand, wrist, knee and ankle of 14 healthy volunteers, of three anatomic pathology tissue specimens and of three formalin-fixed specimens were obtained. Normal anatomy was identified and compared with the three gross anatomic pathology sections. The skin, hands, wrists and ankles of 30 patients were examined and a variety of pathological lesions were detected, including cutaneous neoplasms and ulceration, acute and chronic tendon lesions and pathologic features of the bone and wrist. Based on the excellent imaging of anatomic detail and superior contrast resolution, high resolution MRI proved an important complement for preoperative diagnosis. (orig.)

  16. Strut fracture and disc embolization of a Björk-Shiley mitral valve prosthesis: localization of embolized disc by computerized axial tomography.

    Science.gov (United States)

    Larrieu, A J; Puglia, E; Allen, P

    1982-08-01

    The case of a patient who survived strut fracture and embolization of a Björk-Shiley mitral prosthetic disc is presented. Prompt surgical treatment was directly responsible for survival. In addition, computerized axial tomography of the abdomen aided in localizing and retrieving the embolized disc, which was lodged at the origin of the superior mesenteric artery. A review of similar case reports from the literature supports our conclusions that the development of acute heart failure and absent or muffled prosthetic heart sounds in a patient with a Björk-Shiley prosthetic heart valve inserted prior to 1978 should raise the possibility of valve dysfunction and lead to early reoperation.

  17. Dose profile study on computerized tomography scanning of skull with simulator object; Estudo do perfil de dose em varreduras de TC de cranio com objeto simulador

    Energy Technology Data Exchange (ETDEWEB)

    Mourao, A.P., E-mail: aprata@des.cefetmg.b [Centro Federal de Educacao Tecnologica de Minas Gerais (CEFET/MG), Belo Horizonte, MG (Brazil). Nucleo de Engenharia Hospitalar; Alonso, Thessa C.; Silva, Teogenes A. da, E-mail: alonso@cdtn.b, E-mail: silvata@@cdtn.b [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)

    2011-10-26

    This work presents a comparison among the dose profiles in scanning of computerized tomography of a simulator object of PMMA in its periphery region. To obtain the deposited dose at the PMMA thermoluminescent dosemeters were used positioned at the interior of PMMA simulated object longitudinal to periphery and at the center of cylinder (positions denominated North, South, East, West and Center). Eight scanning were performed of simulator object using the routine protocol for skull in eight different services of radiodiagnostic by TC

  18. Hybrid Single Photon Emission Computed Tomography/Computed Tomography Sulphur Colloid Scintigraphy in Focal Nodular Hyperplasia

    International Nuclear Information System (INIS)

    Bhoil, Amit; Gayana, Shankramurthy; Sood, Ashwani; Bhattacharya, Anish; Mittal, Bhagwant Rai

    2013-01-01

    It is important to differentiate focal nodular hyperplasia (FNH), a benign condition of liver most commonly affecting women, from other neoplasm such as hepatic adenoma and metastasis. The functional reticuloendothelial features of FNH can be demonstrated by scintigraphy. We present a case of breast cancer in whom fluorodeoxyglucose positron emission tomography/computerized tomography (CT) showed a homogenous hyperdense lesion in liver, which on Tc99m sulfur colloid single-photon emission computed tomography/CT was found to have increased focal tracer uptake suggestive of FNH

  19. High-resolution computed tomography in silicosis: correlation with chest radiography and pulmonary function tests

    Energy Technology Data Exchange (ETDEWEB)

    Lopes, Agnaldo Jose [Universidade do Estado do Rio de Janeiro (UERJ), RJ (Brazil). Pedro Ernesto Univ. Hospital. Dept. of Respiratory Function]. E-mail: phel.lop@uol.com.br; Mogami, Roberto; Capone, Domenico; Jansen, Jose Manoel [Universidade do Estado do Rio de Janeiro (UERJ), RJ (Brazil). School of Medical Sciences; Tessarollo, Bernardo [Universidade do Estado do Rio de Janeiro (UERJ), RJ (Brazil). Dept. of Radiology and Diagnostic Image; Melo, Pedro Lopes de [Universidade do Estado do Rio de Janeiro (UERJ), RJ (Brazil). Inst. of Biology

    2008-05-15

    Objective: To correlate tomographic findings with pulmonary function findings, as well as to compare chest X-ray findings with high-resolution computed tomography (HRCT) findings, in patients with silicosis. Methods: A cross-sectional study was conducted in 44 non-smoking patients without a history of tuberculosis. Chest X-ray findings were classified according to the International Labour Organization recommendations. Using a semiquantitative system, the following HRCT findings were measured: the full extent of pulmonary involvement; parenchymal opacities; and emphysema. Spirometry and forced oscillation were performed. Pulmonary volumes were evaluated using the helium dilution method, and diffusing capacity of the lung for carbon monoxide was assessed. Results: Of the 44 patients studied, 41 were male. The mean age was 48.4 years. There were 4 patients who were classified as category 0 based on X-ray findings and as category 1 based on HRCT findings. Using HRCT scans, we identified progressive massive fibrosis in 33 patients, compared with only 23 patients when X-rays were used. Opacity score was found to correlate most closely with airflow, DLCO and compliance. Emphysema score correlated inversely with volume, DLCO and airflow. In this sample of patients presenting a predominance of large opacities (75% of the individuals), the deterioration of pulmonary function was associated with the extent of structural changes. Conclusions: In the early detection of silicosis and the identification of progressive massive fibrosis, HRCT scans are superior to X-rays. (author)

  20. High-resolution computed tomography in silicosis: correlation with chest radiography and pulmonary function tests

    International Nuclear Information System (INIS)

    Lopes, Agnaldo Jose; Mogami, Roberto; Capone, Domenico; Jansen, Jose Manoel; Tessarollo, Bernardo; Melo, Pedro Lopes de

    2008-01-01

    Objective: To correlate tomographic findings with pulmonary function findings, as well as to compare chest X-ray findings with high-resolution computed tomography (HRCT) findings, in patients with silicosis. Methods: A cross-sectional study was conducted in 44 non-smoking patients without a history of tuberculosis. Chest X-ray findings were classified according to the International Labour Organization recommendations. Using a semiquantitative system, the following HRCT findings were measured: the full extent of pulmonary involvement; parenchymal opacities; and emphysema. Spirometry and forced oscillation were performed. Pulmonary volumes were evaluated using the helium dilution method, and diffusing capacity of the lung for carbon monoxide was assessed. Results: Of the 44 patients studied, 41 were male. The mean age was 48.4 years. There were 4 patients who were classified as category 0 based on X-ray findings and as category 1 based on HRCT findings. Using HRCT scans, we identified progressive massive fibrosis in 33 patients, compared with only 23 patients when X-rays were used. Opacity score was found to correlate most closely with airflow, DLCO and compliance. Emphysema score correlated inversely with volume, DLCO and airflow. In this sample of patients presenting a predominance of large opacities (75% of the individuals), the deterioration of pulmonary function was associated with the extent of structural changes. Conclusions: In the early detection of silicosis and the identification of progressive massive fibrosis, HRCT scans are superior to X-rays. (author)