WorldWideScience

Sample records for high-altitude color infrared

  1. A preliminary training guide for utilizing high-altitude, color-infrared photography in compiling soil maps

    Science.gov (United States)

    Weaver, J. E.; Parkhurst, W. H.; Ward, J. F.; Almond, R. H.

    1977-01-01

    Instruction for acquiring and analytically processing small-scale color-infrared photography to perform a soil resources inventory over forests of the southern U.S. is provided. Planning the project; acquiring aerial photography, materials, equipment and supplemental data; and preparing the photography for analysis are discussed. The procedures for preparing ancillary and primary component overlays are discussed. The use of correlation charts and dichotomous keys for mountain landforms, water regime, and vegetation is explained.

  2. INFRARED COLOR-COLOR DIAGRAMS FOR AGB STARS

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    Kyung-Won Suh

    2007-09-01

    Full Text Available We present infrared color-color diagrams of AGB stars from the observations at near and mid infrared bands. We compile the observations for hundreds of OH/IR stars and carbon stars using the data from the Midcourse Space Experiment (MSX, the two micron sky survey (2MASS, and the IRAS point source catalog (PSC. We compare the observations with the theoretical evolutionary tracks of AGB stars. From the new observational data base and the theoretical evolution tracks, we discuss the meaning of the infrared color-color diagrams at different wavelengths.

  3. Land use inventory of Salt Lake County, Utah from color infrared aerial photography 1982

    Science.gov (United States)

    Price, K. P.; Willie, R. D.; Wheeler, D. J.; Ridd, M. K.

    1983-01-01

    The preparation of land use maps of Salt Lake County, Utah from high altitude color infrared photography is described. The primary purpose of the maps is to aid in the assessment of the effects of urban development on the agricultural land base and water resources. The first stage of map production was to determine the categories of land use/land cover and the mapping unit detail. The highest level of interpretive detail was given to the land use categories found in the agricultural or urbanized portions of the county; these areas are of primary interest with regard to the consumptive use of water from surface streams and wells. A slightly lower level of mapping detail was given to wetland environments; areas to which water is not purposely diverted by man but which have a high consumptive rate of water use. Photos were interpreted on the basis of color, tone, texture, and pattern, together with features of the topographic, hydrologic, and ecological context.

  4. GOODS-HERSCHEL: SEPARATING HIGH-REDSHIFT ACTIVE GALACTIC NUCLEI AND STAR-FORMING GALAXIES USING INFRARED COLOR DIAGNOSTICS

    Energy Technology Data Exchange (ETDEWEB)

    Kirkpatrick, Allison; Pope, Alexandra [Department of Astronomy, University of Massachusetts, Amherst, MA 01002 (United States); Charmandaris, Vassilis [Department of Physics and Institute of Theoretical and Computational Physics, University of Crete, GR-71003, Heraklion (Greece); Daddi, Emmanuele; Elbaz, David; Pannella, Maurilio; Aussel, Herve; Dasyra, Kalliopi; Leiton, Roger [Laboratoire AIM, CEA/DSM-CNRS-Universite Paris Diderot, Irfu/SAp, Orme des Merisiers, F-91191 Gif-sur-Yvette (France); Hwang, Ho Seong [Smithsonian Astrophysical Observatory, 60 Garden Street, Cambridge, MA 02138 (United States); Scott, Douglas; Magnelli, Benjamin; Popesso, Paola [Max-Planck-Institut fuer Extraterrestrische Physik (MPE), Postfach 1312, D-85741, Garching (Germany); Altieri, Bruno; Coia, Daniela; Valtchanov, Ivan [Herschel Science Centre, European Space Astronomy Centre, Villanueva de la Canada, E-28691 Madrid (Spain); Dannerbauer, Helmut [Universitaet Wien, Institut fuer Astrophysik, Tuerkenschanzstrasse 17, A-1180 Wien (Austria); Dickinson, Mark; Kartaltepe, Jeyhan [National Optical Astronomy Observatory, 950 North Cherry Avenue, Tucson, AZ 85719 (United States); Magdis, Georgios [Department of Physics, University of Oxford, Keble Road, Oxford OX1 3RH (United Kingdom)

    2013-02-15

    We have compiled a large sample of 151 high-redshift (z = 0.5-4) galaxies selected at 24 {mu}m (S {sub 24} > 100 {mu}Jy) in the GOODS-N and ECDFS fields for which we have deep Spitzer IRS spectroscopy, allowing us to decompose the mid-infrared spectrum into contributions from star formation and activity in the galactic nuclei. In addition, we have a wealth of photometric data from Spitzer IRAC/MIPS and Herschel PACS/SPIRE. We explore how effective different infrared color combinations are at separating our mid-IR spectroscopically determined active galactic nuclei from our star-forming galaxies. We look in depth at existing IRAC color diagnostics, and we explore new color-color diagnostics combining mid-IR, far-IR, and near-IR photometry, since these combinations provide the most detail about the shape of a source's IR spectrum. An added benefit of using a color that combines far-IR and mid-IR photometry is that it is indicative of the power source driving the IR luminosity. For our data set, the optimal color selections are S {sub 250}/S {sub 24} versus S {sub 8}/S {sub 3.6} and S {sub 100}/S {sub 24} versus S {sub 8}/S {sub 3.6}; both diagnostics have {approx}10% contamination rate in the regions occupied primarily by star-forming galaxies and active galactic nuclei, respectively. Based on the low contamination rate, these two new IR color-color diagnostics are ideal for estimating both the mid-IR power source of a galaxy when spectroscopy is unavailable and the dominant power source contributing to the IR luminosity. In the absence of far-IR data, we present color diagnostics using the Wide-field Infrared Survey Explorer mid-IR bands which can efficiently select out high-z (z {approx} 2) star-forming galaxies.

  5. The evolution of Titan's high-altitude aerosols under ultraviolet irradiation

    Science.gov (United States)

    Carrasco, Nathalie; Tigrine, Sarah; Gavilan, Lisseth; Nahon, Laurent; Gudipati, Murthy S.

    2018-04-01

    The Cassini-Huygens space mission revealed that Titan's thick brownish haze is initiated high in the atmosphere at an altitude of about 1,000 km, before a slow transportation down to the surface. Close to the surface, at altitudes below 130 km, the Huygens probe provided information on the chemical composition of the haze. So far, we have not had insights into the possible photochemical evolution of the aerosols making up the haze during their descent. Here, we address this atmospheric aerosol aging process, simulating in the laboratory how solar vacuum ultraviolet irradiation affects the aerosol optical properties as probed by infrared spectroscopy. An important evolution was found that could explain the apparent contradiction between the nitrogen-poor infrared spectroscopic signature observed by Cassini below 600 km of altitude in Titan's atmosphere and a high nitrogen content as measured by the aerosol collector and pyrolyser of the Huygens probe at the surface of Titan.

  6. HIGH-ALTITUDE ILLNESS

    Directory of Open Access Journals (Sweden)

    Dwitya Elvira

    2015-05-01

    Full Text Available AbstrakHigh-altitude illness (HAI merupakan sekumpulan gejala paru dan otak yang terjadi pada orang yang baru pertama kali mendaki ke ketinggian. HAI terdiri dari acute mountain sickness (AMS, high-altitude cerebral edema (HACE dan high-altitude pulmonary edema (HAPE. Tujuan tinjauan pustaka ini adalah agar dokter dan wisatawan memahami risiko, tanda, gejala, dan pengobatan high-altitude illness. Perhatian banyak diberikan terhadap penyakit ini seiring dengan meningkatnya popularitas olahraga ekstrim (mendaki gunung tinggi, ski dan snowboarding dan adanya kemudahan serta ketersediaan perjalanan sehingga jutaan orang dapat terpapar bahaya HAI. Di Pherice, Nepal (ketinggian 4343 m, 43% pendaki mengalami gejala AMS. Pada studi yang dilakukan pada tempat wisata di resort ski Colorado, Honigman menggambarkan kejadian AMS 22% pada ketinggian 1850 m sampai 2750 m, sementara Dean menunjukkan 42% memiliki gejala pada ketinggian 3000 m. Aklimatisasi merupakan salah satu tindakan pencegahan yang dapat dilakukan sebelum pendakian, selain beberapa pengobatan seperti asetazolamid, dexamethasone, phosopodiestrase inhibitor, dan ginko biloba.Kata kunci: high-altitude illness, acute mountain sickness, edema cerebral, pulmonary edema AbstractHigh-altitude illness (HAI is symptoms of lung and brain that occurs in people who first climb to altitude. HAI includes acute mountain sickness (AMS, high-altitude cerebral edema (HACE and high altitude pulmonary edema (HAPE. The objective of this review was to understand the risks, signs, symptoms, and treatment of high-altitude illness. The attention was given to this disease due to the rising popularity of extreme sports (high mountain climbing, skiing and snowboarding and the ease and availability of the current travelling, almost each year, millions of people could be exposed to the danger of HAI. In Pherice, Nepal (altitude 4343 m, 43% of climbers have symptoms of AMS. Furthermore, in a study conducted at sites in

  7. Scene recognition and colorization for vehicle infrared images

    Science.gov (United States)

    Hou, Junjie; Sun, Shaoyuan; Shen, Zhenyi; Huang, Zhen; Zhao, Haitao

    2016-10-01

    In order to make better use of infrared technology for driving assistance system, a scene recognition and colorization method is proposed in this paper. Various objects in a queried infrared image are detected and labelled with proper categories by a combination of SIFT-Flow and MRF model. The queried image is then colorized by assigning corresponding colors according to the categories of the objects appeared. The results show that the strategy here emphasizes important information of the IR images for human vision and could be used to broaden the application of IR images for vehicle driving.

  8. 2014 - Color & Infrared - Northeastern Vermont (0.5m)

    Data.gov (United States)

    Vermont Center for Geographic Information — (Link to Metadata) This metadata record describes the acquisition and production of natural color and color infrared digital ground orthoimagery covering a portion...

  9. Athletes at High Altitude.

    Science.gov (United States)

    Khodaee, Morteza; Grothe, Heather L; Seyfert, Jonathan H; VanBaak, Karin

    2016-01-01

    Athletes at different skill levels perform strenuous physical activity at high altitude for a variety of reasons. Multiple team and endurance events are held at high altitude and may place athletes at increased risk for developing acute high altitude illness (AHAI). Training at high altitude has been a routine part of preparation for some of the high level athletes for a long time. There is a general belief that altitude training improves athletic performance for competitive and recreational athletes. A review of relevant publications between 1980 and 2015 was completed using PubMed and Google Scholar. Clinical review. Level 3. AHAI is a relatively uncommon and potentially serious condition among travelers to altitudes above 2500 m. The broad term AHAI includes several syndromes such as acute mountain sickness (AMS), high altitude pulmonary edema (HAPE), and high altitude cerebral edema (HACE). Athletes may be at higher risk for developing AHAI due to faster ascent and more vigorous exertion compared with nonathletes. Evidence regarding the effects of altitude training on athletic performance is weak. The natural live high, train low altitude training strategy may provide the best protocol for enhancing endurance performance in elite and subelite athletes. High altitude sports are generally safe for recreational athletes, but they should be aware of their individual risks. Individualized and appropriate acclimatization is an essential component of injury and illness prevention.

  10. The use of high altitude remote sensing in determining existing vegetation and monitoring ecological stress

    Science.gov (United States)

    Foster, K.; Garcia, A.

    1972-01-01

    High altitude color and multispectral black and white photography was used to survey existing vegetation and soil conditions on the Empire Ranch where large scale development will soon begin. Utilizing stereo pairs of the high altitude color photography, four vegetation classifications were discernable as a function of topography and foliage characteristics. In contrast to the undeveloped Ranch, the same photography was used to detect environmental changes in the Tucson metropolitan area as a result of rapid urbanization. The most prevalent change related to development is the removal of vegetation in high density areas to allow for housing starts. Erosion then occurs where vegetation has been removed.

  11. High altitude illness

    Science.gov (United States)

    Hartman-Ksycińska, Anna; Kluz-Zawadzka, Jolanta; Lewandowski, Bogumił

    High-altitude illness is a result of prolonged high-altitude exposure of unacclimatized individuals. The illness is seen in the form of acute mountain sickness (AMS) which if not treated leads to potentially life-threatening high altitude pulmonary oedema and high-altitude cerebral oedema. Medical problems are caused by hypobaric hypoxia stimulating hypoxia-inducible factor (HIF) release. As a result, the central nervous system, circulation and respiratory system function impairment occurs. The most important factor in AMS treatment is acclimatization, withdrawing further ascent and rest or beginning to descent; oxygen supplementation, and pharmacological intervention, and, if available, a portable hyperbaric chamber. Because of the popularity of high-mountain sports and tourism better education of the population at risk is essential.

  12. 2016 - Color & Infrared - Rutland and Windsor (0.15m)

    Data.gov (United States)

    Vermont Center for Geographic Information — (Link to Metadata) This metadata record describes the acquisition and production of natural color and color infrared digital ground orthoimagery covering a portion...

  13. 2016 - Color & Infrared - Rutland and Windsor (0.3m)

    Data.gov (United States)

    Vermont Center for Geographic Information — (Link to Metadata) This metadata record describes the acquisition and production of natural color and color infrared digital ground orthoimagery covering a portion...

  14. Cropping management using color and color infrared aerial photographs

    Science.gov (United States)

    Morgan, K. M.; Morris-Jones, D. R.; Lee, G. B.; Kiefer, R. W.

    1979-01-01

    The Universal Soil Loss Equation (USLE) is a widely accepted tool for erosion prediction and conservation planning. Solving this equation yields the long-term average annual soil loss that can be expected from rill and inter-rill erosion. In this study, manual interpretation of color and color infrared 70 mm photography at the scale of 1:60,000 is used to determine the cropping management factor in the USLE. Accurate information was collected about plowing practices and crop residue cover (unharvested vegetation) for the winter season on agricultural land in Pheasant Branch Creek watershed in Dane County, Wisconsin.

  15. Star-forming Galaxies as AGN Imposters? A Theoretical Investigation of the Mid-infrared Colors of AGNs and Extreme Starbursts

    Science.gov (United States)

    Satyapal, Shobita; Abel, Nicholas P.; Secrest, Nathan J.

    2018-05-01

    We conduct for the first time a theoretical investigation of the mid-infrared spectral energy distribution (SED) produced by dust heated by an active galactic nucleus (AGN) and an extreme starburst. These models employ an integrated modeling approach using photoionization and stellar population synthesis models in which both the line and emergent continuum is predicted from gas exposed to the ionizing radiation from a young starburst and an AGN. In this work, we focus on the infrared colors from the Wide-field Infrared Survey Explorer, predicting the dependence of the colors on the input radiation field, the interstellar medium conditions, the obscuring column, and the metallicity. We find that an extreme starburst can mimic an AGN in two band mid-infrared color cuts employed in the literature. However, the three-band color cuts employed in the literature require starbursts with extremely high ionization parameters or gas densities. We show that the extreme mid-infrared colors seen in some blue compact dwarf galaxies are not due to metallicity but rather a combination of high ionization parameters and high column densities. Based on our theoretical calculations, we present a theoretical mid-infrared color cut that will exclude even the most extreme starburst that we have modeled in this work. The theoretical AGN demarcation region presented here can be used to identify elusive AGN candidates for future follow-up studies with the James Webb Space Telescope. The full suite of simulated SEDs are available online.

  16. Brain Food at High Altitude.

    Science.gov (United States)

    Jain, Vishal

    2016-01-01

    Scenic view at high altitude is a pleasure to the eyes, but it has some shortcoming effects as well. High altitude can be divided into different categories, i.e., high altitude (3000-5000 ft), very high altitude (5000-8000 ft), and extreme altitude (above 8000 ft). Much of the population resides at high altitude, and others go there for tourism. Military personnel are also posted there to defend boundaries. As we ascent to high altitude, partial pressure of oxygen reduces, whereas concentration remains the same; this reduces the availability of oxygen to different body parts. This pathophysiological condition is known as hypobaric hypoxia (HH) which leads to oxidative stress and further causes cognitive dysfunction in some cases. Hypoxia causes neurodegeneration in different brain regions; however, the hippocampus is found to be more prone in comparison to other brain regions. As the hippocampus is affected most, therefore, spatial memory is impaired most during such condition. This chapter will give a brief review of the damaging effect of high altitude on cognition and also throw light on possible herbal interventions at high altitude, which can improve cognitive performance as well as provide protection against the deteriorating effect of hypobaric hypoxia at high altitude.

  17. Research on Methods of Infrared and Color Image Fusion Based on Wavelet Transform

    Directory of Open Access Journals (Sweden)

    Zhao Rentao

    2014-06-01

    Full Text Available There is significant difference in the imaging features of infrared image and color image, but their fusion images also have very good complementary information. In this paper, based on the characteristics of infrared image and color image, first of all, wavelet transform is applied to the luminance component of the infrared image and color image. In multi resolution the relevant regional variance is regarded as the activity measure, relevant regional variance ratio as the matching measure, and the fusion image is enhanced in the process of integration, thus getting the fused images by final synthesis module and multi-resolution inverse transform. The experimental results show that the fusion image obtained by the method proposed in this paper is better than the other methods in keeping the useful information of the original infrared image and the color information of the original color image. In addition, the fusion image has stronger adaptability and better visual effect.

  18. Visual Infrared Color Gradients in Elliptical Galaxies

    NARCIS (Netherlands)

    Peletier, R. F.; Valentijn, E. A.; Jameson, R. F.; de Zeeuw, P.T.

    1987-01-01

    Simultaneous measurements for visual and visual-infrared colors provide the means to determine both the average temperature of the giant branch and the turnoff-temperature of the main sequence. This allows to model fractional contributions of different populations, including age- and

  19. SPITZER OBSERVATIONS OF PASSIVE AND STAR-FORMING EARLY-TYPE GALAXIES: AN INFRARED COLOR-COLOR SEQUENCE

    International Nuclear Information System (INIS)

    Temi, Pasquale; Brighenti, Fabrizio; Mathews, William G.

    2009-01-01

    We describe the infrared properties of a large sample of early-type galaxies, comparing data from the Spitzer archive with Ks-band emission from the Two Micron All Sky Survey. While most representations of this data result in correlations with large scatter, we find a remarkably tight relation among colors formed by ratios of luminosities in Spitzer-Multiband Imaging Photometer bands (24, 70, and 160 μm) and the Ks band. Remarkably, this correlation among E and S0 galaxies follows that of nearby normal galaxies of all morphological types. In particular, the tight infrared color-color correlation for S0 galaxies alone follows that of the entire Hubble sequence of normal galaxies, roughly in order of galaxy type from ellipticals to spirals to irregulars. The specific star formation rate (SFR) of S0 galaxies estimated from the 24 μm luminosity increases with decreasing K-band luminosity (or stellar mass) from essentially zero, as with most massive ellipticals, to rates typical of irregular galaxies. Moreover, the luminosities of the many infrared-luminous S0 galaxies can significantly exceed those of the most luminous (presumably post-merger) E galaxies. SFRs in the most infrared-luminous S0 galaxies approach 1-10 solar masses per year. Consistently, with this picture we find that while most early-type galaxies populate an infrared red sequence, about 24% of the objects (mostly S0s) are in an infrared blue cloud together with late-type galaxies. For those early-type galaxies also observed at radio frequencies, we find that the far-infrared luminosities correlate with the mass of neutral and molecular hydrogen, but the scatter is large. This scatter suggests that the star formation may be intermittent or that similar S0 galaxies with cold gaseous disks of nearly equal mass can have varying radial column density distributions that alter the local and global SFRs.

  20. High Altitude and Heart

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    Murat Yalcin

    2011-04-01

    Full Text Available Nowadays, situations associated with high altitude such as mountaineering, aviation increasingly draw the attention of people. Gas pressure decreases and hypoxia is encountered when climbing higher. Physiological and pathological responses of human body to different heights are different. Therefore, physiological and pathological changes that may occur together with height and to know the clinical outcomes of these are important . Acute mountain sickness caused by high altitude and high altitude cerebral edema are preventable diseases with appropriate precautions. Atmospheric oxygen decreasing with height, initiates many adaptive mechanisms. These adaptation mechanisms and acclimatization vary widely among individuals because of reasons such as environmental factors, exercise and cold. High altitude causes different changes in the cardiovascular system with various mechanisms. Although normal individuals easily adapt to these changes, this situation can lead to undesirable results in people with heart disease. For this reason, it should be known the effective evaluation of the people with known heart disease before traveling to high altitude and the complications due to the changes with height and the recommendations can be made to these patients. [TAF Prev Med Bull 2011; 10(2.000: 211-222

  1. High-altitude pulmonary hypertension

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    X-Q. Xu

    2009-03-01

    Full Text Available High-altitude pulmonary hypertension (HAPH is a specific disease affecting populations that live at high elevations. The prevalence of HAPH among those residing at high altitudes needs to be further defined. Whereas reduction in nitric oxide production may be one mechanism for the development of HAPH, the roles of endothelin-1 and prostaglandin I2 pathways in the pathogenesis of HAPH deserve further study. Although some studies have suggested that genetic factors contribute to the pathogenesis of HAPH, data published to date are insufficient for the identification of a significant number of gene polymorphims in HAPH. The clinical presentation of HAPH is nonspecific. Exertional dyspnoea is the most common symptom and signs related to right heart failure are common in late stages of HAPH. Echocardiography is the most useful screening tool and right heart catheterisation is the gold standard for the diagnosis of HAPH. The ideal management for HAPH is migration to lower altitudes. Phosphodiesterase 5 is an attractive drug target for the treatment of HAPH. In addition, acetazolamide is a promising therapeutic agent for high-altitude pulmonary hypertension. To date, no evidence has confirmed whether endothelin-receptor antagonists have efficacy in the treatment of high-altitude pulmonary hypertension.

  2. Numerical research on the thermal performance of high altitude scientific balloons

    International Nuclear Information System (INIS)

    Dai, Qiumin; Xing, Daoming; Fang, Xiande; Zhao, Yingjie

    2017-01-01

    Highlights: • A model is presented to evaluate the IR radiation between translucent surfaces. • Comprehensive ascent and thermal models of balloons are established. • The effect of IR transmissivity on film temperature distribution is unneglectable. • Atmospheric IR radiation is the primary thermal factor of balloons at night. • Solar radiation is the primary thermal factor of balloons during the day. - Abstract: Internal infrared (IR) radiation is an important factor that affects the thermal performance of high altitude balloons. The internal IR radiation is commonly neglected or treated as the IR radiation between opaque gray bodies. In this paper, a mathematical model which considers the IR transmissivity of the film is proposed to estimate the internal IR radiation. Comprehensive ascent and thermal models for high altitude scientific balloons are established. Based on the models, thermal characteristics of a NASA super pressure balloon are simulated. The effects of film IR property on the thermal behaviors of the balloon are discussed in detail. The results are helpful for the design and operation of high altitude scientific balloons.

  3. System for beaming power from earth to a high altitude platform

    Science.gov (United States)

    Friedman, Herbert W.; Porter, Terry J.

    2002-01-01

    Power is transmitted to a high altitude platform by an array of diode pumped solid state lasers each operated at a single range of laser wavelengths outside of infrared and without using adaptive optics. Each laser produces a beam with a desired arrival spot size. An aircraft avoidance system uses a radar system for automatic control of the shutters of the lasers.

  4. Acute high-altitude sickness

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    Andrew M. Luks

    2017-02-01

    Full Text Available At any point 1–5 days following ascent to altitudes ≥2500 m, individuals are at risk of developing one of three forms of acute altitude illness: acute mountain sickness, a syndrome of nonspecific symptoms including headache, lassitude, dizziness and nausea; high-altitude cerebral oedema, a potentially fatal illness characterised by ataxia, decreased consciousness and characteristic changes on magnetic resonance imaging; and high-altitude pulmonary oedema, a noncardiogenic form of pulmonary oedema resulting from excessive hypoxic pulmonary vasoconstriction which can be fatal if not recognised and treated promptly. This review provides detailed information about each of these important clinical entities. After reviewing the clinical features, epidemiology and current understanding of the pathophysiology of each disorder, we describe the current pharmacological and nonpharmacological approaches to the prevention and treatment of these diseases.

  5. Near-infrared polarization and color of Comet Halley: What can we learn about the grains

    International Nuclear Information System (INIS)

    Brooke, T.Y.; Knacke, R.F.

    1988-01-01

    The near infrared polarization and JHK colors of light scattered by dust grains in comet Halley were measured over a wide range in phase angle and heliocentric distance. Colors were redder than solar with no statistically significant variation with phase angle, heliocentric distance, or pre- and post-perihelion. This suggests that the grain population did not change drastically over time and that the data may be combined and modeled. However, short term variations in visible polarization and dust albedo were seen in Halley. Also, near infrared colors became systematically bluer after the observations were completed. The near infrared colors of Halley fall in the range of those of other comets. The near infrared polarization is similar to the visible polarization of Halley and other comets in showing a negative branch at small phase angles and an approximately linear rise toward positive values at larger phase angles. Mie theory calculations and a size distribution based on spacecraft data were used to model the near infrared polarization and color of comet Halley. Numerous lines of evidence point to the presence of dark, absorbing, probably carbonaceous materials in comets

  6. Image Analysis for Facility Siting: a Comparison of Lowand High-altitude Image Interpretability for Land Use/land Cover Mapping

    Science.gov (United States)

    Borella, H. M.; Estes, J. E.; Ezra, C. E.; Scepan, J.; Tinney, L. R.

    1982-01-01

    For two test sites in Pennsylvania the interpretability of commercially acquired low-altitude and existing high-altitude aerial photography are documented in terms of time, costs, and accuracy for Anderson Level II land use/land cover mapping. Information extracted from the imagery is to be used in the evaluation process for siting energy facilities. Land use/land cover maps were drawn at 1:24,000 scale using commercially flown color infrared photography obtained from the United States Geological Surveys' EROS Data Center. Detailed accuracy assessment of the maps generated by manual image analysis was accomplished employing a stratified unaligned adequate class representation. Both 'area-weighted' and 'by-class' accuracies were documented and field-verified. A discrepancy map was also drawn to illustrate differences in classifications between the two map scales. Results show that the 1:24,000 scale map set was more accurate (99% to 94% area-weighted) than the 1:62,500 scale set, especially when sampled by class (96% to 66%). The 1:24,000 scale maps were also more time-consuming and costly to produce, due mainly to higher image acquisition costs.

  7. THE CONTRIBUTION OF TP-AGB STARS TO THE MID-INFRARED COLORS OF NEARBY GALAXIES

    International Nuclear Information System (INIS)

    Chisari, Nora E.; Kelson, Daniel D.

    2012-01-01

    We study the mid-infrared color space of 30 galaxies from the Spitzer Infrared Nearby Galaxies Survey (SINGS) survey for which Sloan Digital Sky Survey data are also available. We construct two-color maps for each galaxy and compare them to results obtained from combining Maraston evolutionary synthesis models, galactic thermally pulsating asymptotic giant branch (TP-AGB) colors, and smooth star formation histories. For most of the SINGS sample, the spatially extended mid-IR emission seen by Spitzer in normal galaxies is consistent with our simple model in which circumstellar dust from TP-AGB stars dominates at 8 and 24 μm. There is a handful of exceptions that we identify as galaxies that have high star formation rates presumably with star formation histories that cannot be assumed to be smooth, or anemic galaxies, which were depleted of their H I at some point during their evolution and have very low ongoing star formation rates.

  8. THE CONTRIBUTION OF TP-AGB STARS TO THE MID-INFRARED COLORS OF NEARBY GALAXIES

    Energy Technology Data Exchange (ETDEWEB)

    Chisari, Nora E. [Department of Astrophysical Sciences, Princeton University, 4 Ivy Lane, Princeton, NJ 08544 (United States); Kelson, Daniel D., E-mail: nchisari@astro.princeton.edu [Observatories of the Carnegie Institution of Science, 813 Santa Barbara St., Pasadena, CA 91101 (United States)

    2012-07-10

    We study the mid-infrared color space of 30 galaxies from the Spitzer Infrared Nearby Galaxies Survey (SINGS) survey for which Sloan Digital Sky Survey data are also available. We construct two-color maps for each galaxy and compare them to results obtained from combining Maraston evolutionary synthesis models, galactic thermally pulsating asymptotic giant branch (TP-AGB) colors, and smooth star formation histories. For most of the SINGS sample, the spatially extended mid-IR emission seen by Spitzer in normal galaxies is consistent with our simple model in which circumstellar dust from TP-AGB stars dominates at 8 and 24 {mu}m. There is a handful of exceptions that we identify as galaxies that have high star formation rates presumably with star formation histories that cannot be assumed to be smooth, or anemic galaxies, which were depleted of their H I at some point during their evolution and have very low ongoing star formation rates.

  9. Diagnostic criteria of high-altitude de-adaptation for high-altitude migrants returning to the plains: a multicenter, randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Qi-quan ZHOU

    2012-02-01

    Full Text Available Objective  To investigate the diagnostic method of high-altitude de-adaptation and constitute the diagnostic criteria of high-altitude de-adaptation for people returning to the plains from high-altitude. Methods  Epidemiological survey and clinical multicenter randomized controlled studies were used to determine/perform blood picture, routine urine analysis, routine stool examination, myocardial enzymes, liver and kidney functions, nerve function, sex hormone, microalbuminuria, ECG, echocardiography, pulmonary function tests, and so on, in 3011 subjects after they returned to the plains from high-altitude. The diagnostic criteria of high-altitude de-adaptation were formulated by a comparative analysis of the obtained data with those of healthy subjects living in the same area, altitude, and age. The regularity and characteristics of high-altitude de-adaptation syndrome were found and diagnostic criteria for high-altitude de-adaptation was established based on the results. Results  The investigative results showed that the incidence of high-altitude de-adaptation syndrome was found in 84.36% of population returning to the plains from high-altitude. About 60% of them were considered to have mild reactions, 30% medium, and only 10% were severe. The lower the altitude they returned to, the longer the duration of stay in highland, and the heavier the labor they engaged in high altitude, the higher the incidence rate of high-altitude de-adaptation syndrome was. Patients with high-altitude de-adaptation syndrome exhibited hematological abnormality and abnormal ventricular function, especially the right ventricular diastolic function after returning for 1 year to 5 years. Long-term hypoxia exposure often caused obvious change in cardiac morphology with left and right ventricular hypertrophy, particularly the right ventricle. In addition, low blood pressure and low pulse pressure were found at times. Microalbuminuria was found in some high-altitude de

  10. Infrared observations of giant elliptical galaxies: (V-K) colors and the infrared Hubble diagram

    International Nuclear Information System (INIS)

    Grasdalen, G.L.

    1980-01-01

    The (V-K) colors of giant elliptical galaxies as a function of redshift are discussed. Present data are consistent with mild color evolution at z approximately 0.45. An infrared Hubble (redshift-magnitude) diagram is given. Cosmological models with q 0 =0 and no luminosity evolution are clearly excluded by the present data. A wide variety of models including those with q 0 =0 are permissible if luminosity evolution is included. Instrumental and programmatic implications of these results are summarized. (Auth.)

  11. Image analysis for facility siting: a comparison of low- and high-altitude image interpretability for land use/land cover mapping

    International Nuclear Information System (INIS)

    Borella, H.M.; Estes, J.E.; Ezra, C.E.; Scepan, J.; Tinney, L.R.

    1982-01-01

    For two test sites in Pennsylvania the interpretability of commercially acquired low-altitude and existing high-altitude aerial photography are documented in terms of time, costs, and accuracy for Anderson Level II land use/land cover mapping. Information extracted from the imagery is to be used in the evaluation process for siting energy facilities. Land use/land cover maps were drawn at 1:24,000 scale using commercially flown color infrared photography obtained from the United States Geological Surveys' EROS Data Center. Detailed accuracy assessment of the maps generated by manual image analysis was accomplished employing a stratified unaligned adequate class representation. Both are-weighted and by-class accuracies were documented and field-verified. A discrepancy map was also drawn to illustrate differences in classifications between the two map scales. Results show that the 1:24,000 scale map set was accurate (99% to 94% area-weighted) than the 1:62,500 scale set, especially when sampled by class (96% to 66%). The 1:24,000 scale maps were also more time-consuming and costly to produce, due mainly to higher image acquisition costs

  12. Analysis of high-altitude de-acclimatization syndrome after exposure to high altitudes: a cluster-randomized controlled trial.

    Science.gov (United States)

    He, Binfeng; Wang, Jianchun; Qian, Guisheng; Hu, Mingdong; Qu, Xinming; Wei, Zhenghua; Li, Jin; Chen, Yan; Chen, Huaping; Zhou, Qiquan; Wang, Guansong

    2013-01-01

    The syndrome of high-altitude de-acclimatization commonly takes place after long-term exposure to high altitudes upon return to low altitudes. The syndrome severely affects the returnee's quality of life. However, little attention has been paid to careful characterization of the syndrome and their underlying mechanisms. Male subjects from Chongqing (n = 67, 180 m) and Kunming (n = 70, 1800 m) visited a high-altitude area (3650 m) about 6 months and then returned to low-altitude. After they came back, all subjects were evaluated for high-altitude de-acclimatization syndrome on the 3(rd), 50(th), and 100(th). Symptom scores, routine blood and blood gas tests, and myocardial zymograms assay were used for observation their syndrome. The results showed that the incidence and severity of symptoms had decreased markedly on the 50(th) and 100(th) days, compared with the 3(rd) day. The symptom scores and incidence of different symptoms were lower among subjects returning to Kunming than among those returning to Chongqing. On the 3(rd) day, RBC, Hb, Hct, CK, CK-MB, and LDH values were significantly lower than values recorded at high altitudes, but they were higher than baseline values. On the 50(th) day, these values were not different from baseline values, but LDH levels did not return to baseline until the 100(th) day. These data show that, subjects who suffered high-altitude de-acclimatization syndrome, the recovery fully processes takes a long time (≥ 100(th) days). The appearance of the syndrome is found to be related to the changes in RBC, Hb, Hct, CK, CK-MB, and LDH levels, which should be caused by reoxygenation after hypoxia.

  13. Two-color mid-infrared spectroscopy of optically doped semiconductors

    International Nuclear Information System (INIS)

    Forcales, M.; Klik, M.A.J.; Vinh, N.Q.; Phillips, J.; Wells, J-P.R.; Gregorkiewicz, T.

    2003-01-01

    Optical doping is an attractive method to tailor photonic properties of semiconductor matrices for development of solid-state electroluminescent structures. For practical applications, thermal stability of emission obtained from these materials is required. Thermal processes can be conveniently investigated by two-color spectroscopy in the visible and the mid-infrared. Free-electron laser is a versatile high-brilliance source of radiation in the latter spectral range. In this contribution, we briefly review some of the results obtained recently by the two-color spectroscopy with a free-electron laser in different semiconductors optically doped with rare earth and transition metal ions. Effects leading to both enhancement and quenching of emission from optical dopants will be presented. For InP:Yb, Si:Er, and Si:Cu activation of particular optically induced non-radiative recombination paths will be shown. For Si:Er and Si:Ag, observation of a low temperature optical memory effect will be reported

  14. Shilajit: A panacea for high-altitude problems.

    Science.gov (United States)

    Meena, Harsahay; Pandey, H K; Arya, M C; Ahmed, Zakwan

    2010-01-01

    High altitude problems like hypoxia, acute mountain sickness, high altitude cerebral edema, pulmonary edema, insomnia, tiredness, lethargy, lack of appetite, body pain, dementia, and depression may occur when a person or a soldier residing in a lower altitude ascends to high-altitude areas. These problems arise due to low atmospheric pressure, severe cold, high intensity of solar radiation, high wind velocity, and very high fluctuation of day and night temperatures in these regions. These problems may escalate rapidly and may sometimes become life-threatening. Shilajit is a herbomineral drug which is pale-brown to blackish-brown, is composed of a gummy exudate that oozes from the rocks of the Himalayas in the summer months. It contains humus, organic plant materials, and fulvic acid as the main carrier molecules. It actively takes part in the transportation of nutrients into deep tissues and helps to overcome tiredness, lethargy, and chronic fatigue. Shilajit improves the ability to handle high altitudinal stresses and stimulates the immune system. Thus, Shilajit can be given as a supplement to people ascending to high-altitude areas so that it can act as a "health rejuvenator" and help to overcome high-altitude related problems.

  15. Early history of high-altitude physiology.

    Science.gov (United States)

    West, John B

    2016-02-01

    High-altitude physiology can be said to have begun in 1644 when Torricelli described the first mercury barometer and wrote the immortal words "We live submerged at the bottom of an ocean of the element air." Interestingly, the notion of atmospheric pressure had eluded his teacher, the great Galileo. Blaise Pascal was responsible for describing the fall in pressure with increasing altitude, and Otto von Guericke gave a dramatic demonstration of the enormous force that could be developed by atmospheric pressure. Robert Boyle learned of Guericke's experiment and, with Robert Hooke, constructed the first air pump that allowed small animals to be exposed to a low pressure. Hooke also constructed a small low-pressure chamber and exposed himself to a simulated altitude of about 2400 meters. With the advent of ballooning, humans were rapidly exposed to very low pressures, sometimes with tragic results. For example, the French balloon, Zénith, rose to over 8000 m, and two of the three aeronauts succumbed to the hypoxia. Paul Bert was the first person to clearly state that the deleterious effects of high altitude were caused by the low partial pressure of oxygen (PO2), and later research was accelerated by high-altitude stations and expeditions to high altitude. © 2015 New York Academy of Sciences.

  16. Forward looking anomaly detection via fusion of infrared and color imagery

    Science.gov (United States)

    Stone, K.; Keller, J. M.; Popescu, M.; Havens, T. C.; Ho, K. C.

    2010-04-01

    This paper develops algorithms for the detection of interesting and abnormal objects in color and infrared imagery taken from cameras mounted on a moving vehicle, observing a fixed scene. The primary purpose of detection is to cue a human-in-the-loop detection system. Algorithms for direct detection and change detection are investigated, as well as fusion of the two. Both methods use temporal information to reduce the number of false alarms. The direct detection algorithm uses image self-similarity computed between local neighborhoods to determine interesting, or unique, parts of an image. Neighborhood similarity is computed using Euclidean distance in CIELAB color space for the color imagery, and Euclidean distance between grey levels in the infrared imagery. The change detection algorithm uses the affine scale-invariant feature transform (ASIFT) to transform multiple background frames into the current image space. Each transformed image is then compared to the current image, and the multiple outputs are fused to produce a single difference image. Changes in lighting and contrast between the background run and the current run are adjusted for in both color and infrared imagery. Frame-to-frame motion is modeled using a perspective transformation, the parameters of which are computed using scale-invariant feature transform (SIFT) keypoint correspondences. This information is used to perform temporal accumulation of single frame detections for both the direct detection and change detection algorithms. Performance of the proposed algorithms is evaluated on multiple lanes from a data collection at a US Army test site.

  17. High Altitude Launch for a Practical SSTO

    Science.gov (United States)

    Landis, Geoffrey A.; Denis, Vincent

    2003-01-01

    Existing engineering materials allow the constuction of towers to heights of many kilometers. Orbital launch from a high altitude has significant advantages over sea-level launch due to the reduced atmospheric pressure, resulting in lower atmospheric drag on the vehicle and allowing higher rocket engine performance. High-altitude launch sites are particularly advantageous for single-stage to orbit (SSTO) vehicles, where the payload is typically 2% of the initial launch mass. An earlier paper enumerated some of the advantages of high altitude launch of SSTO vehicles. In this paper, we calculate launch trajectories for a candidate SSTO vehicle, and calculate the advantage of launch at launch altitudes 5 to 25 kilometer altitudes above sea level. The performance increase can be directly translated into increased payload capability to orbit, ranging from 5 to 20% increase in the mass to orbit. For a candidate vehicle with an initial payload fraction of 2% of gross lift-off weight, this corresponds to 31% increase in payload (for 5-km launch altitude) to 122% additional payload (for 25-km launch altitude).

  18. Ages of galaxy bulges and disks from optical and near-infrared colors

    NARCIS (Netherlands)

    Peletier, RF; Balcells, M

    We compare optical and near-infrared colors of disks and bulges in a diameter-limited sample of inclined, bright, nearby, early-type spirals. Color profiles along wedge apertures at 15 degrees from the major axis and on the minor axis on the side of the galaxy opposite to the dust lane are used to

  19. NOAA JPSS Visible Infrared Imaging Radiometer Suite (VIIRS) Ocean Color/Chlorophyll (OCC) Environmental Data Record (EDR) from IDPS

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains a high quality operational Environmental Data Record (EDR) of Ocean Color/Chlorophyll (OCC) from the Visible Infrared Imaging Radiometer Suite...

  20. Roles of the color antisymmetric ghost propagator in the Infrared QCD

    International Nuclear Information System (INIS)

    Furui, S.

    2009-01-01

    The results of Coulomb gauge and Landau gauge lattice QCD simulation do not agree completely with continuum theory. There are indications that the ghost propagator in the infrared region has strong fluctuation whose modulus is compatible with that of the color diagonal ghost propagator. After presenting lattice simulation of configurations produced with Kogut-Susskind fermion (MILC collaboration) and those with domain wall fermion (RBC/UKQCD collaboration), I investigate in triple gluon vertex and the ghost-gluon-ghost vertex how the square of the color antisymmetric ghost contributes. Then the effect of the vertex correction to the gluon propagator and the ghost propagator is investigated. Recent Dyson-Schwinger equation analysis suggests the ghost dressing function G(0) = finite and no infrared enhancement or a G = 0. But the ghost propagator renormalized by the loop containing a product of color antisymmetric ghost is expected to behave as [cc] r = - (G(q 2 ))/(q 2 ) with G(q 2 ) ∝ q -2aG with a G = 0.5, if the fixed point scenario is valid. I interpret the a G = 0 solution should contain a vertex correction. The infrared exponent of our lattice Landau gauge gluon propagator of the RBC/UKQCD is a D = - 0.5 and that of MILC is about - 0.7. A possible interpretation of the origin of the fluctuation is given. (author)

  1. DLR HABLEG- High Altitude Balloon Launched Experimental Glider

    Science.gov (United States)

    Wlach, S.; Schwarzbauch, M.; Laiacker, M.

    2015-09-01

    The group Flying Robots at the DLR Institute of Robotics and Mechatronics in Oberpfaffenhofen conducts research on solar powered high altitude aircrafts. Due to the high altitude and the almost infinite mission duration, these platforms are also denoted as High Altitude Pseudo-Satellites (HAPS). This paper highlights some aspects of the design, building, integration and testing of a flying experimental platform for high altitudes. This unmanned aircraft, with a wingspan of 3 m and a mass of less than 10 kg, is meant to be launched as a glider from a high altitude balloon in 20 km altitude and shall investigate technologies for future large HAPS platforms. The aerodynamic requirements for high altitude flight included the development of a launch method allowing for a safe transition to horizontal flight from free-fall with low control authority. Due to the harsh environmental conditions in the stratosphere, the integration of electronic components in the airframe is a major effort. For regulatory reasons a reliable and situation dependent flight termination system had to be implemented. In May 2015 a flight campaign was conducted. The mission was a full success demonstrating that stratospheric research flights are feasible with rather small aircrafts.

  2. High-altitude adaptations in vertebrate hemoglobins

    DEFF Research Database (Denmark)

    Weber, Roy E.

    2007-01-01

    Vertebrates at high altitude are subjected to hypoxic conditions that challenge aerobic metabolism. O2 transport from the respiratory surfaces to tissues requires matching between the O2 loading and unloading tensions and theO2-affinity of blood, which is an integrated function of hemoglobin......, birds and ectothermic vertebrates at high altitude....

  3. Silicon-Vacancy Color Centers in Nanodiamonds: Cathodoluminescence Imaging Marker in the Near Infrared

    OpenAIRE

    Zhang, Huiliang; Aharonovich, Igor; Glenn, David R.; Schalek, R.; Magyar, Andrew P.; Lichtman, Jeff W.; Hu, Evelyn L.; Walsworth, Ronald L.

    2013-01-01

    We demonstrate that nanodiamonds fabricated to incorporate silicon-vacancy (Si-V) color centers provide bright, spectrally narrow, and stable cathodoluminescence (CL) in the near-infrared. Si-V color centers containing nanodiamonds are promising as non-bleaching optical markers for correlated CL and secondary electron microscopy, including applications to nanoscale bioimaging.

  4. Color Segmentation Approach of Infrared Thermography Camera Image for Automatic Fault Diagnosis

    International Nuclear Information System (INIS)

    Djoko Hari Nugroho; Ari Satmoko; Budhi Cynthia Dewi

    2007-01-01

    Predictive maintenance based on fault diagnosis becomes very important in current days to assure the availability and reliability of a system. The main purpose of this research is to configure a computer software for automatic fault diagnosis based on image model acquired from infrared thermography camera using color segmentation approach. This technique detects hot spots in equipment of the plants. Image acquired from camera is first converted to RGB (Red, Green, Blue) image model and then converted to CMYK (Cyan, Magenta, Yellow, Key for Black) image model. Assume that the yellow color in the image represented the hot spot in the equipment, the CMYK image model is then diagnosed using color segmentation model to estimate the fault. The software is configured utilizing Borland Delphi 7.0 computer programming language. The performance is then tested for 10 input infrared thermography images. The experimental result shows that the software capable to detect the faulty automatically with performance value of 80 % from 10 sheets of image input. (author)

  5. Color Vision Changes and Effects of High Contrast Visor Use at Simulated Cabin Altitudes

    Science.gov (United States)

    2016-06-08

    Jefferson Davis Highway, Suite 1204, Arlington, VA 22202-4302. Respondents should be aware that notwithstanding any other provision of law, no person...Morris DS, Kalson NS, Wright AD, Imray CHE, et al. Changes to colour vision on exposure to high altitude. J R Army Med Corps. 2011; 157(1):107-109...4. Richalet JP, Duval-Arnould G, Darnaud B, Keromes A, Rutgers V. Modification of colour vision in the green/red axis in acute and chronic

  6. High-Altitude Illnesses: Physiology, Risk Factors, Prevention, and Treatment

    Directory of Open Access Journals (Sweden)

    Andrew T. Taylor

    2011-01-01

    Full Text Available High-altitude illnesses encompass the pulmonary and cerebral syndromes that occur in non-acclimatized individuals after rapid ascent to high altitude. The most common syndrome is acute mountain sickness (AMS which usually begins within a few hours of ascent and typically consists of headache variably accompanied by loss of appetite, nausea, vomiting, disturbed sleep, fatigue, and dizziness. With millions of travelers journeying to high altitudes every year and sleeping above 2,500 m, acute mountain sickness is a wide-spread clinical condition. Risk factors include home elevation, maximum altitude, sleeping altitude, rate of ascent, latitude, age, gender, physical condition, intensity of exercise, pre-acclimatization, genetic make-up, and pre-existing diseases. At higher altitudes, sleep disturbances may become more profound, mental performance is impaired, and weight loss may occur. If ascent is rapid, acetazolamide can reduce the risk of developing AMS, although a number of high-altitude travelers taking acetazolamide will still develop symptoms. Ibuprofen can be effective for headache. Symptoms can be rapidly relieved by descent, and descent is mandatory, if at all possible, for the management of the potentially fatal syndromes of high-altitude pulmonary and cerebral edema. The purpose of this review is to combine a discussion of specific risk factors, prevention, and treatment options with a summary of the basic physiologic responses to the hypoxia of altitude to provide a context for managing high-altitude illnesses and advising the non-acclimatized high-altitude traveler.

  7. Can High Altitude Influence Cytokines and Sleep?

    Directory of Open Access Journals (Sweden)

    Valdir de Aquino Lemos

    2013-01-01

    Full Text Available The number of persons who relocate to regions of high altitude for work, pleasure, sport, or residence increases every year. It is known that the reduced supply of oxygen (O2 induced by acute or chronic increases in altitude stimulates the body to adapt to new metabolic challenges imposed by hypoxia. Sleep can suffer partial fragmentation because of the exposure to high altitudes, and these changes have been described as one of the responsible factors for the many consequences at high altitudes. We conducted a review of the literature during the period from 1987 to 2012. This work explored the relationships among inflammation, hypoxia and sleep in the period of adaptation and examined a novel mechanism that might explain the harmful effects of altitude on sleep, involving increased Interleukin-1 beta (IL-1β, Interleukin-6 (IL-6, and tumor necrosis factor-alpha (TNF-α production from several tissues and cells, such as leukocytes and cells from skeletal muscle and brain.

  8. Can High Altitude Influence Cytokines and Sleep?

    Science.gov (United States)

    de Aquino Lemos, Valdir; dos Santos, Ronaldo Vagner Thomatieli; Lira, Fabio Santos; Rodrigues, Bruno; Tufik, Sergio; de Mello, Marco Tulio

    2013-01-01

    The number of persons who relocate to regions of high altitude for work, pleasure, sport, or residence increases every year. It is known that the reduced supply of oxygen (O2) induced by acute or chronic increases in altitude stimulates the body to adapt to new metabolic challenges imposed by hypoxia. Sleep can suffer partial fragmentation because of the exposure to high altitudes, and these changes have been described as one of the responsible factors for the many consequences at high altitudes. We conducted a review of the literature during the period from 1987 to 2012. This work explored the relationships among inflammation, hypoxia and sleep in the period of adaptation and examined a novel mechanism that might explain the harmful effects of altitude on sleep, involving increased Interleukin-1 beta (IL-1β), Interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α) production from several tissues and cells, such as leukocytes and cells from skeletal muscle and brain. PMID:23690660

  9. The Impact of Altitude on Sleep-Disordered Breathing in Children Dwelling at High Altitude: A Crossover Study.

    Science.gov (United States)

    Hughes, Benjamin H; Brinton, John T; Ingram, David G; Halbower, Ann C

    2017-09-01

    Sleep-disordered breathing (SDB) is prevalent among children and is associated with adverse health outcomes. Worldwide, approximately 250 million individuals reside at altitudes higher than 2000 meters above sea level (masl). The effect of chronic high-altitude exposure on children with SDB is unknown. This study aims to determine the impact of altitude on sleep study outcomes in children with SDB dwelling at high altitude. A single-center crossover study was performed to compare results of high-altitude home polysomnography (H-PSG) with lower altitude laboratory polysomnography (L-PSG) in school-age children dwelling at high altitude with symptoms consistent with SDB. The primary outcome was apnea-hypopnea index (AHI), with secondary outcomes including obstructive AHI; central AHI; and measures of oxygenation, sleep quality, and pulse rate. Twelve participants were enrolled, with 10 included in the final analysis. Median altitude was 1644 masl on L-PSG and 2531 masl on H-PSG. Median AHI was 2.40 on L-PSG and 10.95 on H-PSG. Both obstructive and central respiratory events accounted for the difference in AHI. Oxygenation and sleep fragmentation were worse and pulse rate higher on H-PSG compared to L-PSG. These findings reveal a clinically substantial impact of altitude on respiratory, sleep, and cardiovascular outcomes in children with SDB who dwell at high altitude. Within this population, L-PSG underestimates obstructive sleep apnea and central sleep apnea compared to H-PSG. Given the shortage of high-altitude pediatric sleep laboratories, these results suggest a role for home sleep apnea testing for children residing at high altitude. © Sleep Research Society 2017. Published by Oxford University Press on behalf of the Sleep Research Society. All rights reserved. For permissions, please e-mail journals.permissions@oup.com.

  10. The use of color infrared aerial photography in determining salt marsh vegetation and delimiting man-made structures of Lynnhaven Bay, Virginia. M.S. Thesis

    Science.gov (United States)

    Holman, R. E., III

    1974-01-01

    Color infrared aerial photography was found to be superior to color aerial photography in an ecological study of Lynnhaven Bay, Virginia. The research was divided into three phases: (1) Determination of the feasibility of correlating color infrared aerial photography with saline wetland species composition and zonation patterns, (2) determination of the accuracy of the aerial interpretation and problems related to the aerial method used; and (3) comparison of developed with undeveloped areas along Lynnhaven Bay's shoreline. Wetland species composition and plant community zonation bands were compared with aerial infrared photography and resulted in a high degree of correlation. Problems existed with changing physical conditions; time of day, aircraft angle and sun angle, making it necessary to use several different characteristics in wetland species identification. The main characteristics used were known zonation patterns, textural signatures and color tones. Lynnhaven Bay's shoreline was 61.5 percent developed.

  11. The sky's the limit!

    Science.gov (United States)

    ,

    1983-01-01

    The National High Altitude Photography Program NHAP-The National High Altitude Photography program- is making recent aerial photographs, both black-and-white and color infrared, more easily accessible to you.

  12. A color fusion method of infrared and low-light-level images based on visual perception

    Science.gov (United States)

    Han, Jing; Yan, Minmin; Zhang, Yi; Bai, Lianfa

    2014-11-01

    The color fusion images can be obtained through the fusion of infrared and low-light-level images, which will contain both the information of the two. The fusion images can help observers to understand the multichannel images comprehensively. However, simple fusion may lose the target information due to inconspicuous targets in long-distance infrared and low-light-level images; and if targets extraction is adopted blindly, the perception of the scene information will be affected seriously. To solve this problem, a new fusion method based on visual perception is proposed in this paper. The extraction of the visual targets ("what" information) and parallel processing mechanism are applied in traditional color fusion methods. The infrared and low-light-level color fusion images are achieved based on efficient typical targets learning. Experimental results show the effectiveness of the proposed method. The fusion images achieved by our algorithm can not only improve the detection rate of targets, but also get rich natural information of the scenes.

  13. Acute high-altitude illness | Hofmeyr | South African Medical Journal

    African Journals Online (AJOL)

    A substantial proportion of South Africa (SA)'s population lives at high altitude (>1 500 m), and many travel to very high altitudes (>3 500 m) for tourism, business, recreation or religious pilgrimages every year. Despite this, knowledge of acute altitude illnesses is poor among SA doctors. At altitude, the decreasing ambient ...

  14. The sleep of elite athletes at sea level and high altitude: a comparison of sea-level natives and high-altitude natives (ISA3600).

    Science.gov (United States)

    Roach, Gregory D; Schmidt, Walter F; Aughey, Robert J; Bourdon, Pitre C; Soria, Rudy; Claros, Jesus C Jimenez; Garvican-Lewis, Laura A; Buchheit, Martin; Simpson, Ben M; Hammond, Kristal; Kley, Marlen; Wachsmuth, Nadine; Gore, Christopher J; Sargent, Charli

    2013-12-01

    Altitude exposure causes acute sleep disruption in non-athletes, but little is known about its effects in elite athletes. The aim of this study was to examine the effects of altitude on two groups of elite athletes, that is, sea-level natives and high-altitude natives. Sea-level natives were members of the Australian under-17 soccer team (n=14). High-altitude natives were members of a Bolivian under-20 club team (n=12). Teams participated in an 18-day (19 nights) training camp in Bolivia, with 6 nights at near sea level in Santa Cruz (430 m) and 13 nights at high altitude in La Paz (3600 m). Sleep was assessed on every day/night using activity monitors. The Australians' sleep was shorter, and of poorer quality, on the first night at altitude compared with sea level. Sleep quality returned to normal by the end of the first week at altitude, but sleep quantity had still not stabilised at its normal level after 2 weeks. The quantity and quality of sleep obtained by the Bolivians was similar, or greater, on all nights at altitude compared with sea level. The Australians tended to obtain more sleep than the Bolivians at sea level and altitude, but the quality of the Bolivians' sleep tended to be better than that of the Australians at altitude. Exposure to high altitude causes acute and chronic disruption to the sleep of elite athletes who are sea-level natives, but it does not affect the sleep of elite athletes who are high-altitude natives.

  15. Preacclimatization in hypoxic chambers for high altitude sojourns.

    Science.gov (United States)

    Küpper, Thomas E A H; Schöffl, Volker

    2010-09-01

    Since hypoxic chambers are more and more available, they are used for preacclimatization to prepare for sojourns at high altitude. Since there are different protocols and the data differ, there is no general consensus about the standard how to perform preacclimatization by simulated altitude. The paper reviews the different types of exposure and focuses on the target groups which may benefit from preacclimatization. Since data about intermittent hypoxia for some hours per day to reduce the incidence of acute mountain sickness differ, it is suggested to perform preacclimatization by sleeping some nights at a simulated altitude which follows the altitude profile of the "gold standard" for high altitude acclimatization.

  16. High-Altitude-Induced alterations in Gut-Immune Axis: A review.

    Science.gov (United States)

    Khanna, Kunjan; Mishra, K P; Ganju, Lilly; Kumar, Bhuvnesh; Singh, Shashi Bala

    2018-03-04

    High-altitude sojourn above 8000 ft is increasing day by day either for pilgrimage, mountaineering, holidaying or for strategic reasons. In India, soldiers are deployed to these high mountains for their duty or pilgrims visit to the holy places, which are located at very high altitude. A large population also resides permanently in high altitude regions. Every year thousands of pilgrims visit Holy cave of Shri Amarnath ji, which is above 15 000 ft. The poor acclimatization to high altitude may cause alteration in immunity. The low oxygen partial pressure may cause alterations in gut microbiota, which may cause changes in gut immunity. Effect of high altitude on gut-associated mucosal system is new area of research. Many studies have been carried out to understand the physiology and immunology behind the high-altitude-induced gut problems. Few interventions have also been discovered to circumvent the problems caused due to high-altitude conditions. In this review, we have discussed the effects of high-altitude-induced changes in gut immunity particularly peyer's patches, NK cells and inflammatory cytokines, secretary immunoglobulins and gut microbiota. The published articles from PubMed and Google scholar from year 1975 to 2017 on high-altitude hypoxia and gut immunity are cited in this review.

  17. The sleep of elite athletes at sea level and high altitude: a comparison of sea-level natives and high-altitude natives (ISA3600)

    Science.gov (United States)

    Roach, Gregory D; Schmidt, Walter F; Aughey, Robert J; Bourdon, Pitre C; Soria, Rudy; Claros, Jesus C Jimenez; Garvican-Lewis, Laura A; Buchheit, Martin; Simpson, Ben M; Hammond, Kristal; Kley, Marlen; Wachsmuth, Nadine; Gore, Christopher J; Sargent, Charli

    2013-01-01

    Background Altitude exposure causes acute sleep disruption in non-athletes, but little is known about its effects in elite athletes. The aim of this study was to examine the effects of altitude on two groups of elite athletes, that is, sea-level natives and high-altitude natives. Methods Sea-level natives were members of the Australian under-17 soccer team (n=14). High-altitude natives were members of a Bolivian under-20 club team (n=12). Teams participated in an 18-day (19 nights) training camp in Bolivia, with 6 nights at near sea level in Santa Cruz (430 m) and 13 nights at high altitude in La Paz (3600 m). Sleep was assessed on every day/night using activity monitors. Results The Australians’ sleep was shorter, and of poorer quality, on the first night at altitude compared with sea level. Sleep quality returned to normal by the end of the first week at altitude, but sleep quantity had still not stabilised at its normal level after 2 weeks. The quantity and quality of sleep obtained by the Bolivians was similar, or greater, on all nights at altitude compared with sea level. The Australians tended to obtain more sleep than the Bolivians at sea level and altitude, but the quality of the Bolivians’ sleep tended to be better than that of the Australians at altitude. Conclusions Exposure to high altitude causes acute and chronic disruption to the sleep of elite athletes who are sea-level natives, but it does not affect the sleep of elite athletes who are high-altitude natives. PMID:24282197

  18. Effects of ascent to high altitude on human antimycobacterial immunity.

    Directory of Open Access Journals (Sweden)

    Sarah Eisen

    Full Text Available Tuberculosis infection, disease and mortality are all less common at high than low altitude and ascent to high altitude was historically recommended for treatment. The immunological and mycobacterial mechanisms underlying the association between altitude and tuberculosis are unclear. We studied the effects of altitude on mycobacteria and antimycobacterial immunity.Antimycobacterial immunity was assayed in 15 healthy adults residing at low altitude before and after they ascended to 3400 meters; and in 47 long-term high-altitude residents. Antimycobacterial immunity was assessed as the extent to which participants' whole blood supported or restricted growth of genetically modified luminescent Bacille Calmette-Guérin (BCG mycobacteria during 96 hours incubation. We developed a simplified whole blood assay that could be used by a technician in a low-technology setting. We used this to compare mycobacterial growth in participants' whole blood versus positive-control culture broth and versus negative-control plasma.Measurements of mycobacterial luminescence predicted the number of mycobacterial colonies cultured six weeks later. At low altitude, mycobacteria grew in blood at similar rates to positive-control culture broth whereas ascent to high altitude was associated with restriction (p ≤ 0.002 of mycobacterial growth to be 4-times less than in culture broth. At low altitude, mycobacteria grew in blood 25-times more than negative-control plasma whereas ascent to high altitude was associated with restriction (p ≤ 0.01 of mycobacterial growth to be only 6-times more than in plasma. There was no evidence of differences in antimycobacterial immunity at high altitude between people who had recently ascended to high altitude versus long-term high-altitude residents.An assay of luminescent mycobacterial growth in whole blood was adapted and found to be feasible in low-resource settings. This demonstrated that ascent to or residence at high altitude was

  19. The use of color infrared photography for wetlands mapping with special reference to shoreline and waterfowl habitat assessment

    Science.gov (United States)

    1973-01-01

    Evaluation of low altitude oblique photography obtained by hand-held cameras was useful in determining specifications of operational mission requirements for conventional smaller-scaled vertical photography. Remote sensing techniques were used to assess the rapid destruction of marsh areas at Pointe Mouillee. In an estuarian environment where shoreline features change yearly, there is a need for revision in existing area maps. A land cover inventory, mapped from aerial photography, provided essential data necessary for determining adjacent lands suitable for marshland development. To quantitatively assess the wetlands environment, a detailed inventory of vegetative communities (19 categories) was made using color infrared photography and intensive ground truth. A carefully selected and well laid-out transect was found to be a key asset to photointerpretation and to the analysis of vegetative conditions. Transect data provided the interpreter with locally representative areas of various vegetative types. This facilitated development of a photointerpretation key. Additional information on vegetative conditions in the area was also obtained by evaluating the transect data.

  20. [Hemoglobin and testosterone: importance on high altitude acclimatization and adaptation].

    Science.gov (United States)

    Gonzales, Gustavo F

    2011-03-01

    The different types of response mechanisms that the organism uses when exposed to hypoxia include accommodation, acclimatization and adaptation. Accommodation is the initial response to acute exposure to high altitude hypoxia and is characterized by an increase in ventilation and heart rate. Acclimatization is observed in individuals temporarily exposed to high altitude, and to some extent, it enables them to tolerate the high altitudes. In this phase, erythropoiesis is increased, resulting in higher hemoglobin and hematocrit levels to improve oxygen delivery capacity. Adaptation is the process of natural acclimatization where genetical variations and acclimatization play a role in allowing subjects to live without any difficulties at high altitudes. Testosterone is a hormone that regulates erythropoiesis and ventilation and could be associated to the processes of acclimatization and adaptation to high altitude. Excessive erythrocytosis, which leads to chronic mountain sickness, is caused by low arterial oxygen saturation, ventilatory inefficiency and reduced ventilatory response to hypoxia. Testosterone increases during acute exposure to high altitude and also in natives at high altitude with excessive erythrocytosis. Results of current research allow us to conclude that increase in serum testosterone and hemoglobin is adequate for acclimatization, as they improve oxygen transport, but not for high altitude adaptation, since high serum testosterone levels are associated to excessive erythrocytosis.

  1. Pathology of high altitude pulmonary oedema

    International Nuclear Information System (INIS)

    Saleem, N.

    2014-01-01

    Objective: To describe autopsy findings in fatal cases of high altitude pulmonary oedema. Study Design: Descriptive study. Place and Duration of Study: The study was carried out between 1999 and 2002 at an army field medical unit in Baltistan, Armed Forces Institute of Pathology, Rawalpindi and Army Medical College, Rawalpindi, Pakistan. Patients and Methods:Autopsies were performed in 17 fatal cases of High Altitude Pulmonary Edema (HAPE) occurring among soldiers serving in Siachen. Results:All cases were males with a mean age of 26.8 years (19-35). The mean altitude at which HAPE occurred was 5192 meters (2895-6492), and the mean duration of stay at these altitudes was 15.3 days (1-30). Eleven individuals had undergone proper acclimatization. The commonest clinical findings were cough (70%), dyspnoea (53%), nausea (47%), headache (41%), vomiting (35%), chest pain (35%) and tightness in chest (24%). Cyanosis and frothy secretions in the nostrils and mouth were present in all but one case. Mean combined weight of lungs was 1470 grams (1070-1810). There was marked congestion of outer and cut surfaces. Interstitial oedema was present in all cases. RBCs and leukocyte infiltrates were seen in 13 and alveolar hyaline membranes in 9 cases. Thrombi were seen in 2 cases. Cerebral oedema was present in 9 cases. Conclusion:HAPE can occur after more than two weeks of stay at high altitudes despite proper acclimatization. Concomitant cerebral oedema is frequently present. Our autopsy findings are consistent with what has been reported previously. (author)

  2. Atmospheric correction using near-infrared bands for satellite ocean color data processing in the turbid western Pacific region.

    Science.gov (United States)

    Wang, Menghua; Shi, Wei; Jiang, Lide

    2012-01-16

    A regional near-infrared (NIR) ocean normalized water-leaving radiance (nL(w)(λ)) model is proposed for atmospheric correction for ocean color data processing in the western Pacific region, including the Bohai Sea, Yellow Sea, and East China Sea. Our motivation for this work is to derive ocean color products in the highly turbid western Pacific region using the Geostationary Ocean Color Imager (GOCI) onboard South Korean Communication, Ocean, and Meteorological Satellite (COMS). GOCI has eight spectral bands from 412 to 865 nm but does not have shortwave infrared (SWIR) bands that are needed for satellite ocean color remote sensing in the turbid ocean region. Based on a regional empirical relationship between the NIR nL(w)(λ) and diffuse attenuation coefficient at 490 nm (K(d)(490)), which is derived from the long-term measurements with the Moderate-resolution Imaging Spectroradiometer (MODIS) on the Aqua satellite, an iterative scheme with the NIR-based atmospheric correction algorithm has been developed. Results from MODIS-Aqua measurements show that ocean color products in the region derived from the new proposed NIR-corrected atmospheric correction algorithm match well with those from the SWIR atmospheric correction algorithm. Thus, the proposed new atmospheric correction method provides an alternative for ocean color data processing for GOCI (and other ocean color satellite sensors without SWIR bands) in the turbid ocean regions of the Bohai Sea, Yellow Sea, and East China Sea, although the SWIR-based atmospheric correction approach is still much preferred. The proposed atmospheric correction methodology can also be applied to other turbid coastal regions.

  3. High altitude organic gold

    DEFF Research Database (Denmark)

    Pouliot, Mariève; Pyakurel, Dipesh; Smith-Hall, Carsten

    2018-01-01

    Ethnopharmacological relevance Ophiocordyceps sinensis (Berk.) G.H.Sung, J.M.Sung, Hywel-Jones & Spatafora, a high altitude Himalayan fungus-caterpillar product found in alpine meadows in China, Bhutan, Nepal, and India, has been used in the Traditional Chinese Medicine system for over 2000 years...

  4. Why Are High Altitude Natives So Strong at High Altitude? Nature vs. Nurture: Genetic Factors vs. Growth and Development.

    Science.gov (United States)

    Brutsaert, Tom

    Among high-altitude natives there is evidence of a general hypoxia tolerance leading to enhanced performance and/or increased capacity in several important domains. These domains likely include an enhanced physical work capacity, an enhanced reproductive capacity, and an ability to resist several common pathologies of chronic high-altitude exposure. The "strength" of the high-altitude native in this regard may have both a developmental and a genetic basis, although there is better evidence for the former (developmental effects) than for the latter. For example, early-life hypoxia exposure clearly results in lung growth and remodeling leading to an increased O2 diffusing capacity in adulthood. Genetic research has yet to reveal a population genetic basis for enhanced capacity in high-altitude natives, but several traits are clearly under genetic control in Andean and Tibetan populations e.g., resting and exercise arterial O2 saturation (SaO2). This chapter reviews the effects of nature and nurture on traits that are relevant to the process of gas exchange, including pulmonary volumes and diffusion capacity, the maximal oxygen consumption (VO2max), the SaO2, and the alveolar-arterial oxygen partial pressure difference (A-aDO2) during exercise.

  5. Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.

    2012-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This DS consists of the locally enhanced ALOS image mosaics for each of the 24 mineral project areas (referred to herein as areas of interest), whose locality names, locations, and main mineral occurrences are shown on the index map of Afghanistan (fig. 1). ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420-500 nanometer, nm), green (520-600 nm), red (610-690 nm), and near-infrared (760-890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520-770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency, but the image processing has altered the original pixel structure and all image values of the JAXA

  6. CAMEX-4 ER-2 HIGH ALTITUDE DROPSONDE V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The CAMEX-4 ER-2 High Altitude Dropsonde dataset was collected by the ER-2 High Altitude Dropsonde System (EHAD), which used dropwinsondes fitted with Global...

  7. Design, Construction and Calibration of a Near-Infrared Four-Color Pyrometry System for Laser-Driven High Pressure Experiments

    Science.gov (United States)

    Ali, S. J.; Jeanloz, R.; Collins, G.; Spaulding, D. K.

    2010-12-01

    Current dynamic compression experiments, using both quasi-isentropic and shock-compression, allow access to pressure-temperature states both on and off the principle Hugoniot and over a wide range of conditions of direct relevance to planetary interiors. Such studies necessitate reliable temperature measurements below 4000-5000 K. Such relatively low temperature states are also of particular interest for materials such as methane and water that do not experience much heating under shock compression. In order to measure these temperatures as a function of time across the sample, a four-color, near-infrared pyrometry system is being developed for use at the Janus laser facility (LLNL) with channels at wavelengths of 932nm-1008nm, 1008nm-1108nm, 1108nm-1208nm, and 1208nm-1300nm. Each color band is fiber-coupled to an InGaAs PIN photodiode with a rise time of less than 60 ps, read using an 18 GHz oscilloscope in order to ensure time resolutions of under 200 ps. This will allow for high temporal resolution measurements of laser-driven shock compression experiments with total durations of 5-15 ns as well as correlation with simultaneous time-resolved velocity interferometry and visual-wavelength pyrometry. Calibration of the system is being accomplished using quartz targets, as the EOS for quartz is well known, along with a calibrated integrating sphere of known spectral radiance.

  8. Effects of altitude and exercise on pulmonary capillary integrity: evidence for subclinical high-altitude pulmonary edema.

    Science.gov (United States)

    Eldridge, Marlowe W; Braun, Ruedi K; Yoneda, Ken Y; Walby, William F

    2006-03-01

    Strenuous exercise may be a significant contributing factor for development of high-altitude pulmonary edema, particularly at low or moderate altitudes. Thus we investigated the effects of heavy cycle ergometer exercise (90% maximal effort) under hypoxic conditions in which the combined effects of a marked increase in pulmonary blood flow and nonuniform hypoxic pulmonary vasoconstriction could add significantly to augment the mechanical stress on the pulmonary microcirculation. We postulated that intense exercise at altitude would result in an augmented permeability edema. We recruited eight endurance athletes and examined their bronchoalveolar lavage fluid (BALF) for red blood cells (RBCs), protein, inflammatory cells, and soluble mediators at 2 and 26 h after intense exercise under normoxic and hypoxic conditions. After heavy exercise, under all conditions, the athletes developed a permeability edema with high BALF RBC and protein concentrations in the absence of inflammation. We found that exercise at altitude (3,810 m) caused significantly greater leakage of RBCs [9.2 (SD 3.1)x10(4) cells/ml] into the alveolar space than that seen with normoxic exercise [5.4 (SD 1.2)x10(4) cells/ml]. At altitude, the 26-h postexercise BALF revealed significantly higher RBC and protein concentrations, suggesting an ongoing capillary leak. Interestingly, the BALF profiles following exercise at altitude are similar to that of early high-altitude pulmonary edema. These findings suggest that pulmonary capillary disruption occurs with intense exercise in healthy humans and that hypoxia augments the mechanical stresses on the pulmonary microcirculation.

  9. Effect of oxygen supplementation in a hatchery at high altitude and ...

    African Journals Online (AJOL)

    The objective of this study was to investigate the effect of oxygen supplementation on broiler eggs in a hatchery at high altitude on the growth performance and ascites syndrome of broilers reared at low altitude. The treatment groups were low altitude with no oxygen supplemented in the hatchery (LA-NOX); high altitude with ...

  10. Chernobyl radioactivity and high altitude air-particulate monitoring at Islamabad

    International Nuclear Information System (INIS)

    Bhatti, M.S.; Ihsanullah; Shafiq, M.; Perveen, N.; Orfi, S.D.

    1987-11-01

    High altitude sampling of air particulates for radioactivity monitoring was conducted at Islamabad after the CHERNOBYL accident. Smears from aeroplanes flying at varying altitudes were collected and analysed for fresh fission products mainly gamma emitters e.g. Ru-103 and Cs-137 etc. The maximum radioactivity observed was of the order of 15Bq/sample for Ru-103 and 9Bq/sample for Cs-137 respectively. The study was purely qualitative in nature indicated the presence of fresh fission radioactivity at high altitudes over Islamabad. For quantitative measurements at high altitudes sophisticated instrumentation/procedure needs to be adopted. (author)

  11. Hemoglobin and testosterone: importance on high altitude acclimatization and adaptation

    OpenAIRE

    Gonzales, Gustavo F.; Jefe de la Unidad de Reproducción, Instituto de Investigaciones de la Altura y Jefe del Laboratorio de Endocrinología y Reproducción, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia. Doctor en Medicina y Doctor en Ciencias. Especialista en Endocrinología.

    2011-01-01

    The different types of response mechanisms that the organism uses when exposed to hypoxia include accommodation, acclimatization and adaptation. Accommodation is the initial response to acute exposure to high altitude hypoxia and is characterized by an increase in ventilation and heart rate. Acclimatization is observed in individuals temporarily exposed to high altitude, and to some extent, it enables them to tolerate the high altitudes. In this phase, erythropoiesis is increased, resulti...

  12. Can people with Raynaud's phenomenon travel to high altitude?

    Science.gov (United States)

    Luks, Andrew M; Grissom, Colin K; Jean, Dominique; Swenson, Erik R

    2009-01-01

    To determine whether high altitude travel adversely affects mountain enthusiasts with Raynaud's phenomenon. Volunteers with Raynaud's phenomenon were recruited using announcements disseminated by organizations dedicated to climbing or wilderness travel and Internet discussion boards dedicated to mountain activities to complete an online, anonymous survey. Survey questions addressed demographic variables, aspects of their Raynaud's phenomenon, and features of their mountain activities. Respondents compared experiences with Raynaud's phenomenon between high (>2440 m; 8000 feet) and low elevations and rated agreement with statements concerning their disease and the effects of high altitude. One hundred forty-two people, 98% of whom had primary Raynaud's phenomenon, completed the questionnaire. Respondents spent 5 to 7 days per month at elevations above 2440 m and engaged in 5.4 +/- 2.0 different activities. Eighty-nine percent of respondents engaged in winter sports and only 22% reported changing their mountain activities because of Raynaud's phenomenon. Respondents reported a variety of tactics to prevent and treat Raynaud's attacks, but only 12% used prophylactic medications. Fifteen percent of respondents reported an episode of frostbite following a Raynaud's phenomenon attack at high altitude. There was considerable heterogeneity in participants' perceptions of the frequency, duration, and severity of attacks at high altitude compared to their home elevation. Motivated individuals with primary Raynaud's phenomenon, employing various prevention and treatment strategies, can engage in different activities, including winter sports, at altitudes above 2440 m. Frostbite may be common in this population at high altitude, and care must be taken to prevent its occurrence.

  13. Infrared and chemical characterization of natural amethysts and prasiolites colored by irradiation

    Directory of Open Access Journals (Sweden)

    Fernando Soares Lameiras

    2009-09-01

    Full Text Available The infrared bands of amethyst and prasiolite samples from different origins were correlated to the trace elements contents. Amethysts have an iron content greater than 20 ppm and a low content of sodium and potassium. Prasiolites have an aluminum content greater than 120 ppm and a higher overall trace elements content, which accounts for a strong absorption between 3200 and 3600 cm-1. Colorless samples of quartz that become amethysts and prasiolites after irradiation have infrared spectra at room temperature with a broad band at 3441 cm-1 and a sharp band at 3595 cm-1. The broad band splits in several bands at low temperatures that are related to AlSi and FeSi. The color of amethysts and prasiolites are assigned to [AlSiO4/h+]º and [FeSiO4/h+]º centers formed by the exposure to ionizing irradiation and to the influence of lattice distortions due to the content of iron as a substitute for silicon and a high content of trace elements of large ionic radius like potassium.

  14. Ocular morbidity among porters at high altitudes.

    Science.gov (United States)

    Gnyawali, Subodh; Shrestha, Gauri Shankar; Khanal, Safal; Dennis, Talisa; Spencer, John C

    2017-01-01

    High altitude, often characterized by settings over 2400m, can be detrimental to the human body and pose a significant risk to ocular health. Reports concerning various ocular morbidities occurring as a consequence of high altitude are limited in the current literature. This study was aimed at evaluating the ocular health of porters working at high altitudesof Himalayas in Nepal. A mobile eye clinic was set up in Ghat and patient data were collected from its out- patient unit by a team of seven optometrists which was run for five days. Ghat is a small village in north-eastern Nepal, located at 2860 m altitude. Travellers walking through the trekking route were invited to get their eyes checked at the clinic. Comprehensive ocular examinations were performed, including visual acuities, objective and subjective refraction, anterior and posterior segment evaluations, and intraocular pressure measurements; blood pressure and blood glucose levels were also measured as required. Ocular therapeutics, prescription glasses, sunglasses and ocular health referrals were provided free of cost as necessary. A total of 1890 people visited the eye clinic, among which 57.4% (n=1084) were porters. Almost half of the porters had an ocular morbidity. Correctable refractive error was most prevalent, with other ocular health-related complications, including dry eye disease, infectious disorders, glaucoma and cataract. Proper provision of regular and effective eye care services should be made more available for those residing at these high altitudes in Nepal. © NEPjOPH.

  15. Shape memory alloy resistance behaviour at high altitude for feedback control

    Science.gov (United States)

    Ng, W. T.; Sedan, M. F.; Abdullah, E. J.; Azrad, S.; Harithuddin, A. S. M.

    2017-12-01

    Many recent aerospace technologies are using smart actuators to reduce the system's complexity and increase its reliability. One such actuator is shape memory alloy (SMA) actuator, which is lightweight, produces high force and large deflection. However, some disadvantages in using SMA actuators have been identified and they include nonlinear response of the strain to input current, hysteresis characteristic that results in inaccurate control and less than optimum system performance, high operating temperatures, slow response and also high requirement of electrical power to obtain the desired actuation forces. It is still unknown if the SMA actuators can perform effectively at high altitude with low surrounding temperature. The work presented here covers the preliminary process of verifying the feasibility of using resistance as feedback control at high altitude for aerospace applications. Temperature and resistance of SMA actuator at high altitude is investigated by conducting an experiment onboard a high altitude balloon. The results from the high altitude experiment indicate that the resistance or voltage drop of the SMA wire is not significantly affected by the low surrounding temperature at high altitude as compared to the temperature of SMA. Resistance feedback control for SMA actuators may be suitable for aerospace applications.

  16. Cortical response to categorical color perception in infants investigated by near-infrared spectroscopy.

    Science.gov (United States)

    Yang, Jiale; Kanazawa, So; Yamaguchi, Masami K; Kuriki, Ichiro

    2016-03-01

    Perceptual color space is continuous; however, we tend to divide it into only a small number of categories. It is unclear whether categorical color perception is obtained solely through the development of the visual system or whether it is affected by language acquisition. To address this issue, we recruited prelinguistic infants (5- to 7-mo-olds) to measure changes in brain activity in relation to categorical color differences by using near-infrared spectroscopy (NIRS). We presented two sets of geometric figures to infants: One set altered in color between green and blue, and the other set altered between two different shades of green. We found a significant increase in hemodynamic responses during the between-category alternations, but not during the within-category alternations. These differences in hemodynamic response based on categorical relationship were observed only in the bilateral occipitotemporal regions, and not in the occipital region. We confirmed that categorical color differences yield behavioral differences in infants. We also observed comparable hemodynamic responses to categorical color differences in adults. The present study provided the first evidence, to our knowledge, that colors of different categories are represented differently in the visual cortex of prelinguistic infants, which implies that color categories may develop independently before language acquisition.

  17. Two-color photoionization and photoelectron studies by combining infrared and vacuum ultraviolet

    International Nuclear Information System (INIS)

    Ng, C.Y.

    2005-01-01

    Recent developments of two-color infrared (IR)-vacuum ultraviolet (VUV) and VUV-IR photoionization and photoelectron detection schemes for spectroscopic studies are described. By preparing molecules in selected rovibrational states by IR excitation prior to VUV-photoionization, state-selected and state-to-state photoionization cross sections can be obtained by IR-VUV-photoionization efficiency (IR-VUV-PIE) and IR-VUV-pulsed field ionization-photoelectron (IR-VUV-PFI-PE) measurements, respectively. Rotationally resolved autoionizing Rydberg states converging to excited ionic states, which cannot be observed by single-photon VUV-PIE measurements, can be examined by the IR-VUV-PIE scheme. By monitoring the photoion and the PFI-PE intensities at a fixed VUV energy as a function of IR frequency, the respective IR photoion and IR absorption spectra of the corresponding neutral molecule can be measured. Two-color VUV-IR photo-induced Rydberg ionization (PIRI) experiment, in which high-n Rydberg states are prepared by VUV-photoexcitation followed by IR-induced autoionization, has also been demonstrated. Since the IR-VUV-PIE, IR-VUV-PFI-PE, and VUV-IR-PIRI methods do not require the existence of a bound intermediate electronic state in the UV and are generally applicable to all molecules, the development of these two-color photoionization and photoelectron schemes is expected to significantly enhance the scope of VUV spectroscopy and chemistry

  18. Phenotypic plasticity and genetic adaptation to high-altitude hypoxia in vertebrates.

    Science.gov (United States)

    Storz, Jay F; Scott, Graham R; Cheviron, Zachary A

    2010-12-15

    High-altitude environments provide ideal testing grounds for investigations of mechanism and process in physiological adaptation. In vertebrates, much of our understanding of the acclimatization response to high-altitude hypoxia derives from studies of animal species that are native to lowland environments. Such studies can indicate whether phenotypic plasticity will generally facilitate or impede adaptation to high altitude. Here, we review general mechanisms of physiological acclimatization and genetic adaptation to high-altitude hypoxia in birds and mammals. We evaluate whether the acclimatization response to environmental hypoxia can be regarded generally as a mechanism of adaptive phenotypic plasticity, or whether it might sometimes represent a misdirected response that acts as a hindrance to genetic adaptation. In cases in which the acclimatization response to hypoxia is maladaptive, selection will favor an attenuation of the induced phenotypic change. This can result in a form of cryptic adaptive evolution in which phenotypic similarity between high- and low-altitude populations is attributable to directional selection on genetically based trait variation that offsets environmentally induced changes. The blunted erythropoietic and pulmonary vasoconstriction responses to hypoxia in Tibetan humans and numerous high-altitude birds and mammals provide possible examples of this phenomenon. When lowland animals colonize high-altitude environments, adaptive phenotypic plasticity can mitigate the costs of selection, thereby enhancing prospects for population establishment and persistence. By contrast, maladaptive plasticity has the opposite effect. Thus, insights into the acclimatization response of lowland animals to high-altitude hypoxia can provide a basis for predicting how altitudinal range limits might shift in response to climate change.

  19. OPTICAL-NEAR-INFRARED COLOR GRADIENTS AND MERGING HISTORY OF ELLIPTICAL GALAXIES

    International Nuclear Information System (INIS)

    Kim, Duho; Im, Myungshin

    2013-01-01

    It has been suggested that merging plays an important role in the formation and the evolution of elliptical galaxies. While gas dissipation by star formation is believed to steepen metallicity and color gradients of the merger products, mixing of stars through dissipation-less merging (dry merging) is believed to flatten them. In order to understand the past merging history of elliptical galaxies, we studied the optical-near-infrared (NIR) color gradients of 204 elliptical galaxies. These galaxies are selected from the overlap region of the Sloan Digital Sky Survey (SDSS) Stripe 82 and the UKIRT Infrared Deep Sky Survey (UKIDSS) Large Area Survey (LAS). The use of optical and NIR data (g, r, and K) provides large wavelength baselines, and breaks the age-metallicity degeneracy, allowing us to derive age and metallicity gradients. The use of the deep SDSS Stripe 82 images makes it possible for us to examine how the color/age/metallicity gradients are related to merging features. We find that the optical-NIR color and the age/metallicity gradients of elliptical galaxies with tidal features are consistent with those of relaxed ellipticals, suggesting that the two populations underwent a similar merging history on average and that mixing of stars was more or less completed before the tidal features disappeared. Elliptical galaxies with dust features have steeper color gradients than the other two types, even after masking out dust features during the analysis, which can be due to a process involving wet merging. More importantly, we find that the scatter in the color/age/metallicity gradients of the relaxed and merging feature types decreases as their luminosities (or masses) increase at M > 10 11.4 M ☉ but stays large at lower luminosities. Mean metallicity gradients appear nearly constant over the explored mass range, but a possible flattening is observed at the massive end. According to our toy model that predicts how the distribution of metallicity gradients

  20. A brief introduction to high altitude nuclear explosion and a review on high altitude nuclear tests of usa and former USSR

    International Nuclear Information System (INIS)

    Sun Jingwen

    1999-11-01

    The author briefly introduces some knowledge about high altitude nuclear explosion (HANE) and presents a general review on high altitude nuclear tests of USA and former USSR. Physical phenomenon generated by HANE is given. The effects of HANE on space flyer, artificial satellite and communication are discussed. Some aspects of a mechanism of antimissile for HANE are described and the effect and role of HANE for USA and USSR are reviewed

  1. Research progress on high altitude retinopathy and application of Traditional Chinese Medicine

    Directory of Open Access Journals (Sweden)

    Hai-Xiang Huang

    2014-11-01

    Full Text Available High altitude retinopathy(HARrefers to the body which can't adapt to the hypobaric hypoxia environment at high altitude leading to retinal diseases, which typically manifested as retinal hemorrhages, optic disc edema and cotton wool spots. With the development of high altitude medicine, HAR become a hot topic of eye research in recent years. New researches show a significantly higher incidence of HAR, and HAR has a close contact with acute mountain sickness, high altitude cerebral edema and high altitude pulmonary edema. A further study in pathogenesis and prevention measures of HAR will promote the prevention of altitude sickness. Traditional Chinese Medicine has achieved good effects in the prevention of altitude sickness, but the effect and mechanism of herbs on HAR has not been reported. Through read and summarize the relevant literatures and reports, the author will give an overview of the research advances on HAR's pathogenesis and application of Traditional Chinese Medicine.

  2. Optical Interference Coatings Design Contest 2013: angle-independent color mirror and shortwave infrared/midwave infrared dichroic beam splitter.

    Science.gov (United States)

    Hendrix, Karen; Kruschwitz, Jennifer D T; Keck, Jason

    2014-02-01

    An angle-independent color mirror and an infrared dichroic beam splitter were the subjects of a design contest held in conjunction with the 2013 Optical Interference Coatings topical meeting of the Optical Society of America. A total of 17 designers submitted 63 designs, 22 for Problem A and 41 for Problem B. The submissions were created through a wide spectrum of design approaches and optimization strategies. Michael Trubetskov and Weidong Shen won the first contest by submitting color mirror designs with a zero color difference (ΔE00) between normal incidence and all other incidence angles up to 60° as well as the thinnest design. Michael Trubetskov also won the second contest by submitting beam-splitter designs that met the required transmission while having the lowest mechanical coating stress and thinnest design. Fabien Lemarchand received the second-place finish for the beam-splitter design. The submitted designs are described and evaluated.

  3. HALESIS projet: Hight Altitude Luminous Events Studied by Infrared Spectro-imagery

    Science.gov (United States)

    Croizé, Laurence; Payan, Sébastien; Bureau, Jérome; Duruisseau, Fabrice; Huret, Nathalie

    2014-05-01

    During the last two decades, the discovery of transient luminous events (TLEs) in the high atmosphere [1], as well as the observation of gamma ray flashes of terrestrial origin (Terrestrial Gamma Flashes or TGF) [2] demonstrated the existence of another interaction processes between the different atmospheric layers (troposphere, stratosphere, mesosphere and ionosphere). Indeed, the frequency of occurrence of these phenomena over thunderstorm cells, and the energies involved provide evidence for an impulsive energy transfer between the troposphere and the highest atmospheric layers, which was not considered before. HALESIS (High Altitude Luminous Events Studied by Infrared Spectro-imagery) is an innovative project based on hyperspectral imagery. The purpose of this experience is to measure the atmospheric perturbation in the minutes following the occurrence of Transient Luminous Events (TLEs) from a stratospheric balloon in the altitude range of 20 to 40 km. The first part of the study has been dedicated to establish the project feasibility. To do that, we have simulated spectral perturbation induced by an isolated blue jet. Theoretical predictions [3] have been used to simulate the radiative perturbation due to O3, NO, NO2, NO+ concentration induced by the blue jet. Simulations have been performed using the line by line radiative transfer model LBLRM [4] taking into account of the Non Local Thermodynamic Equilibrium hypotheses. Then, the expected signatures have been compared to the available instrumentation. During this talk, HALESIS project and the results of the feasibility study will be presented. Then, the estimated spectral signatures will be confronted with the technical capabilities of different kind of hyperspectral imagers. We will conclude on the project feasibility, but also on the challenges that lie ahead for an imager perfectly suited for experiences like HALESIS. 1. Franz R, Nemzek R, Winckler J. Television image of a large upward electrical

  4. Exploring the Limits of High Altitude GPS for Future Lunar Missions

    Science.gov (United States)

    Ashman, Benjamin W.; Parker, Joel J. K.; Bauer, Frank H.; Esswein, Michael

    2018-01-01

    An increasing number of spacecraft are relying on the Global Positioning System (GPS) for navigation at altitudes near or above the GPS constellation itself - the region known as the Space Service Volume (SSV). While the formal definition of the SSV ends at geostationary altitude, the practical limit of high-altitude space usage is not known, and recent missions have demonstrated that signal availability is sufficient for operational navigation at altitudes halfway to the moon. This paper presents simulation results based on a high-fidelity model of the GPS constellation, calibrated and validated through comparisons of simulated GPS signal availability and strength with flight data from recent high-altitude missions including the Geostationary Operational Environmental Satellite 16 (GOES-16) and the Magnetospheric Multiscale (MMS) mission. This improved model is applied to the transfer to a lunar near-rectilinear halo orbit (NRHO) of the class being considered for the international Deep Space Gateway concept. The number of GPS signals visible and their received signal strengths are presented as a function of receiver altitude in order to explore the practical upper limit of high-altitude space usage of GPS.

  5. AltitudeOmics: Resetting of cerebrovascular CO2 reactivity following acclimatization to high altitude

    Directory of Open Access Journals (Sweden)

    Jui-Lin eFan

    2016-01-01

    Full Text Available Previous studies reported enhanced cerebrovascular CO2 reactivity upon ascent to high altitude using linear models. However, there is evidence that this response may be sigmoidal in nature. Moreover, it was speculated that these changes at high altitude are mediated by alterations in acid-base buffering. Accordingly, we reanalyzed previously published data to assess middle cerebral blood flow velocity (MCAv responses to modified rebreathing at sea level (SL, upon ascent (ALT1 and following 16 days of acclimatization (ALT16 to 5,260 m in 21 lowlanders. Using sigmoid curve fitting of the MCAv responses to CO2, we found the amplitude (95% vs. 129%, SL vs. ALT1, 95% confidence intervals (CI [77, 112], [111, 145], respectively, P=0.024 and the slope of the sigmoid response (4.5 vs. 7.5 %/mmHg, SL vs. ALT1, 95% CIs [3.1, 5.9], [6.0, 9.0], respectively, P=0.026 to be enhanced at ALT1, which persisted with acclimatization at ALT16 (amplitude: 177%, 95% CI [139, 215], P<0.001; slope: 10.3 %/mmHg, 95% CI [8.2, 12.5], P=0.003 compared to SL. Meanwhile, the sigmoidal response midpoint was unchanged at ALT1 (SL: 36.5 mmHg; ALT1: 35.4 mmHg, 95% CIs [34.0, 39.0], [33.1, 37.7], respectively, P=0.982, while it was reduced by ~7 mmHg at ALT16 (28.6 mmHg, 95% CI [26.4, 30.8], P=0.001 vs. SL, indicating leftward shift of the cerebrovascular CO2 response to a lower arterial partial pressure of CO2 (PaCO2 following acclimatization to altitude. Sigmoid fitting revealed a leftward shift in the midpoint of the cerebrovascular response curve which could not be observed with linear fitting. These findings demonstrate that there is resetting of the cerebrovascular CO2 reactivity operating point to a lower PaCO2 following acclimatization to high altitude. This cerebrovascular resetting is likely the result of an altered acid-base buffer status resulting from prolonged exposure to the severe hypocapnia associated with ventilatory acclimatization to high altitude.

  6. Radiation exposure and high-altitude flight. NCRP Commentary No. 12

    International Nuclear Information System (INIS)

    1995-01-01

    Enhanced air crew and public radiation exposure while flying at current altitudes and speeds has not been adequately addressed. However, the commercial aircraft industry continues to expand with greater numbers of passengers and more air crews year by year. With the expected expansions in high-altitude flight in the next two decades there will be many more people exposed to higher levels of ionizing radiation than currently. The equivalent dose rates at the higher altitudes are of the order of two to three times those received at current aircraft altitudes, but are not known very well, partly because of limitations in the knowledge of the component radiations, especially the high-energy neutron component. The risks are also more uncertain than for low-LET exposures on the ground because of uncertainty in an average W R to use for high-LET radiations. Exposures of current air crew are presently comparable with the average exposures of other radiation workers on the ground (EPA, 1995). Substantially higher exposures must be expected at high altitudes to air crew (perhaps approaching or possibly exceeding the current limit for workers on the ground). Higher exposures to sensitive groups of the population such as the fetuses carried by pregnant women are of special concern. Therefore, steps must be taken to improve our knowledge base with respect to dose levels and risks at these high altitudes. Following acquisition of this knowledge, modifications in radiation protection practices with respect to air crew and passengers will need to be considered and recommended to assure that adequate radiation protection is provided with respect to high-altitude flight

  7. Autophagy Is a Promoter for Aerobic Exercise Performance during High Altitude Training

    Directory of Open Access Journals (Sweden)

    Ying Zhang

    2018-01-01

    Full Text Available High altitude training is one of the effective strategies for improving aerobic exercise performance at sea level via altitude acclimatization, thereby improving oxygen transport and/or utilization. But its underlying molecular mechanisms on physiological functions and exercise performance of athletes are still vague. More recent evidence suggests that the recycling of cellular components by autophagy is an important process of the body involved in the adaptive responses to exercise. Whether high altitude training can activate autophagy or whether high altitude training can improve exercise performance through exercise-induced autophagy is still unclear. In this narrative review article, we will summarize current research advances in the improvement of exercise performance through high altitude training and its reasonable molecular mechanisms associated with autophagy, which will provide a new field to explore the molecular mechanisms of adaptive response to high altitude training.

  8. Development of a Compact High Altitude Imager and Sounding Radiometer (CHAISR)

    Science.gov (United States)

    Choi, R. K. Y.; Min, S.; Cho, Y. J.; Kim, K. H.; Ha, J. C.; Joo, S. W.

    2017-12-01

    Joint Civilian-Military Committee, under Advisory Council on Science and Technology, Korea, has approved a technology demonstration project for developing a lightweight HALE UAV (High-Altitude, Long Endurance). It aims to operate at lower stratosphere, i.e. altitude of 16 20 km, offering unique observational platform to atmospheric research community as pseudo-satellite. NIMS (National Institute of Meteorological Sciences, Korea) is responsible for a payload for atmospheric science, a Compact High Altitude Imager and Sounding Radiometer (CHAISR) to demonstrate scientific observations at lower stratosphere in the interest of improving numerical weather prediction model. CHAISR consists of three microwave radiometers (MWR) with 16 channel, and medium resolution cameras operating in a visible and infrared spectrum. One of the technological challenges for CHAISR is to accommodate those instruments within 50 W of power consumption. CHAISR will experience temperature up to -75°C, while pressure as low as 50 hPa at operational altitude. It requires passive thermal control of the payload to keep electronic subsystems warm enough for instrument operation with minimal power available. Safety features, such as payload power management and thermal control, are considered with minimal user input. Three radiometers measure atmospheric brightness temperature at frequency at around 20, 40, and 50 GHz. Retrieval process yields temperature and humidity profiles with cross track scan along the flight line. Estimated total weight of all radiometer hardware, from the antennas to data acquisition system, is less than 0.8 kg and a maximum power consumption is 15.2 W. With not enough power for blackbody calibration target, radiometers use zenith sky view at lower stratosphere as an excellent calibration target for a conventional tipping-curve calibration. Spatial distributions of clouds from visible and surface temperature from thermal cameras are used as additional information for

  9. Numerical simulation of the ionization effects of low- and high-altitude nuclear explosions

    International Nuclear Information System (INIS)

    Zhao Zhengyu; Wang Xiang

    2007-01-01

    Low-altitude and high-altitude nuclear explosions are sources of intensive additional ionization in ionosphere. In this paper, in terms of the ionization equilibrium equation system and the equation of energy deposition of radiation in atmosphere, and considering the influence of atmosphere, the temporal and spatial distribution of ionization effects caused by atmospheric nuclear detonation are investigated. The calculated results show that the maximum of additional free electron density produced by low-altitude nuclear explosion is greater than that by the high-altitude nuclear burst. As to the influence of instant nuclear radiation, there is obvious difference between the low-altitude and the high-altitude explosions. The influence range and the continuance time caused by delayed nuclear radiation is less for the low-altitude nuclear detonation than that for the high-altitude one. (authors)

  10. Glucose Homeostasis During Short-term and Prolonged Exposure to High Altitudes

    Science.gov (United States)

    Ader, Marilyn; Bergman, Richard N.

    2015-01-01

    Most of the literature related to high altitude medicine is devoted to the short-term effects of high-altitude exposure on human physiology. However, long-term effects of living at high altitudes may be more important in relation to human disease because more than 400 million people worldwide reside above 1500 m. Interestingly, individuals living at higher altitudes have a lower fasting glycemia and better glucose tolerance compared with those who live near sea level. There is also emerging evidence of the lower prevalence of both obesity and diabetes at higher altitudes. The mechanisms underlying improved glucose control at higher altitudes remain unclear. In this review, we present the most current evidence about glucose homeostasis in residents living above 1500 m and discuss possible mechanisms that could explain the lower fasting glycemia and lower prevalence of obesity and diabetes in this population. Understanding the mechanisms that regulate and maintain the lower fasting glycemia in individuals who live at higher altitudes could lead to new therapeutics for impaired glucose homeostasis. PMID:25675133

  11. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Bakhud mineral district in Afghanistan: Chapter U in Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.; Cagney, Laura E.; Davis, Philip A.

    2013-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Bakhud mineral district, which has industrial fluorite deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420–500 nanometer, nm), green (520–600 nm), red (610–690 nm), and near-infrared (760–890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520–770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency (©JAXA,2006,2007, 2008), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be recreated from this DS. As

  12. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Uruzgan mineral district in Afghanistan: Chapter V in Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.

    2013-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Uruzgan mineral district, which has tin and tungsten deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420–500 nanometer, nm), green (520–600 nm), red (610–690 nm), and near-infrared (760–890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520–770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency (©JAXA, 2008, 2009), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be recreated from this DS. As such

  13. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Katawas mineral district in Afghanistan: Chapter N in Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.; Cagney, Laura E.

    2013-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Katawas mineral district, which has gold deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420-500 nanometer, nm), green (520-600 nm), red (610-690 nm), and near-infrared (760-890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520-770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency (©AXA, 2008), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be recreated from this DS. As such, the DS products match JAXA

  14. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Takhar mineral district in Afghanistan: Chapter Q in Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.; Cagney, Laura E.

    2013-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Takhar mineral district, which has industrial evaporite deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420–500 nanometer, nm), green (520–600 nm), red (610–690 nm), and near-infrared (760–890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520–770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency (©JAXA, 2008), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be recreated from this DS. As such

  15. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Parwan mineral district in Afghanistan: Chapter CC in Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.

    2013-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Parwan mineral district, which has gold and copper deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420–500 nanometer, nm), green (520–600 nm), red (610–690 nm), and near-infrared (760–890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520–770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency (©JAXA,2006, 2007), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be recreated from this DS. As such

  16. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Baghlan mineral district in Afghanistan: Chapter P in Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.; Cagney, Laura E.

    2013-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Baghlan mineral district, which has industrial clay and gypsum deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420–500 nanometer, nm), green (520–600 nm), red (610–690 nm), and near-infrared (760–890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520–770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency (©JAXA, 2006, 2007, 2008), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be recreated from

  17. Generalized math model for simulation of high-altitude balloon systems

    Science.gov (United States)

    Nigro, N. J.; Elkouh, A. F.; Hinton, D. E.; Yang, J. K.

    1985-01-01

    Balloon systems have proved to be a cost-effective means for conducting research experiments (e.g., infrared astronomy) in the earth's atmosphere. The purpose of this paper is to present a generalized mathematical model that can be used to simulate the motion of these systems once they have attained float altitude. The resulting form of the model is such that the pendulation and spin motions of the system are uncoupled and can be analyzed independently. The model is evaluated by comparing the simulation results with data obtained from an actual balloon system flown by NASA.

  18. High Altitude Clear Air Turbulence Project

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Air Force Flight Dynamics Laboratory conducted the High Altitude Clear Air Turbulence Project in the mid 1960s with the intention of better understanding air...

  19. Hemorrhages and hemostasis in guinea-pigs exposed to irradiation at high altitude

    International Nuclear Information System (INIS)

    Tartakovskij, V.N.; Daniyarov, S.B.

    1988-01-01

    Hemorrhagic intensity, hemostasis and blood vessel wall resistance to mechanical effects were studied in guinea-pigs exposed to whole-body irradiation (3.0 Gy). The animals were irradiated at low altitude (760 m above sea level) and at high altitude (3200 m above sea level) after 1 and 31 days of adaptation. It was demonstrated that hemorrhagic intensity in both groups of guinea-pigs irradiated at high altitude was significantly reduced in comparison with that at low altitude. The decrease of radiation-induced hemorrhages at high altitude is associated with less severe changes in thrombopoiesis, blood vessel wall and blood coagulation

  20. Silicon isotope separation utilizing infrared multiphoton dissociation of Si2F6 irradiated with two-color CO2 laser light

    International Nuclear Information System (INIS)

    Yokoyama, Atsushi; Ohba, Hironori; Hashimoto, Masashi; Arai, Shigeyoshi

    2002-01-01

    Silicon isotope separation has been done by utilizing the Infrared Multiphoton Dissociation (IRMPD) of Si 2 F 6 irradiated with two-color CO 2 laser lights. The two-color excitation method improved the separation efficiency keeping the high enrichment factors. For example, 99.74% of 28 Si was obtained at 49.63% dissociation of Si 2 F 6 after the simultaneous irradiation of 200 pulses with 966.23 cm -1 photons (0.084 J/cm 2 ) and 954.55 cm -1 photons (0.658 J/cm 2 ), while 2000 pulses were needed to obtain 99.35% of 28 Si at 35.6% dissociation in the case of only one-color irradiation at 954.55 cm -1 (0.97 J/cm 2 ). (author)

  1. Mechanisms of Memory Dysfunction during High Altitude Hypoxia Training in Military Aircrew.

    Science.gov (United States)

    Nation, Daniel A; Bondi, Mark W; Gayles, Ellis; Delis, Dean C

    2017-01-01

    Cognitive dysfunction from high altitude exposure is a major cause of civilian and military air disasters. Pilot training improves recognition of the early symptoms of altitude exposure so that countermeasures may be taken before loss of consciousness. Little is known regarding the nature of cognitive impairments manifesting within this critical window when life-saving measures may still be taken. Prior studies evaluating cognition during high altitude simulation have predominantly focused on measures of reaction time and other basic attention or motor processes. Memory encoding, retention, and retrieval represent critical cognitive functions that may be vulnerable to acute hypoxic/ischemic events and could play a major role in survival of air emergencies, yet these processes have not been studied in the context of high altitude simulation training. In a series of experiments, military aircrew underwent neuropsychological testing before, during, and after brief (15 min) exposure to high altitude simulation (20,000 ft) in a pressure-controlled chamber. Acute exposure to high altitude simulation caused rapid impairment in learning and memory with relative preservation of basic visual and auditory attention. Memory dysfunction was predominantly characterized by deficiencies in memory encoding, as memory for information learned during high altitude exposure did not improve after washout at sea level. Retrieval and retention of memories learned shortly before altitude exposure were also impaired, suggesting further impairment in memory retention. Deficits in memory encoding and retention are rapidly induced upon exposure to high altitude, an effect that could impact life-saving situational awareness and response. (JINS, 2017, 23, 1-10).

  2. Bacteria isolated from pristine high altitude environments in the Argentinean Andean wetlands: plasmid profile and multiple antibiotic resistance

    International Nuclear Information System (INIS)

    Dib, J.R.; Martinez, M.A.; Sineriz, F.; Farias, M.E.

    2005-01-01

    Full text: Andean wetlands, placed in the North-Western Argentine at 4,600 m altitude, are attractive for both, environmental and biotechnology studies. Most of these wetlands are completely remote and inaccessible, having a high salinity and metal contents, a wide range of daily temperature changes, and an important intensity of solar UV-B radiation. Bacteria isolated from these environments were identified by 16SrDNA sequence and resulted in Gram-positive colored bacteria. Interesting features, to our knowledge never reported so far from bacteria isolates from these pristine high altitude lake-environments, such as similar plasmids profiles and multiple antibiotic resistances are the focus of this work. At least two plasmids were found in all isolates studied by using modifications of the alkaline Iysis method. Their preliminary characterization in this work includes size, incompatibility group through PCR, genetic transference to suitable hosts by transformation and conjugation, and studies of possible relationships of them with antibiotic resistances. (author)

  3. Estimating the top altitude of optically thick ice clouds from thermal infrared satellite observations using CALIPSO data

    Science.gov (United States)

    Minnis, Patrick; Yost, Chris R.; Sun-Mack, Sunny; Chen, Yan

    2008-06-01

    The difference between cloud-top altitude Z top and infrared effective radiating height Z eff for optically thick ice clouds is examined using April 2007 data taken by the Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observations (CALIPSO) and the Moderate-Resolution Imaging Spectroradiometer (MODIS). For even days, the difference ΔZ between CALIPSO Z top and MODIS Z eff is 1.58 +/- 1.26 km. The linear fit between Z top and Z eff , applied to odd-day data, yields a difference of 0.03 +/- 1.21 km and can be used to estimate Z top from any infrared-based Z eff for thick ice clouds. Random errors appear to be due primarily to variations in cloud ice-water content (IWC). Radiative transfer calculations show that ΔZ corresponds to an optical depth of ~1, which based on observed ice-particle sizes yields an average cloud-top IWC of ~0.015 gm-3, a value consistent with in situ measurements. The analysis indicates potential for deriving cloud-top IWC using dual-satellite data.

  4. Colored cool colorants based on rare earth metal ions

    Energy Technology Data Exchange (ETDEWEB)

    Sreeram, Kalarical Janardhanan; Aby, Cheruvathoor Poulose; Nair, Balachandran Unni; Ramasami, Thirumalachari [Chemical Laboratory, Central Leather Research Institute, Council of Scientific and Industrial Research, Adyar, Chennai 600 020 (India)

    2008-11-15

    Colored pigments with high near infrared reflectance and not based on toxic metal ions like cadmium, lead and cobalt are being sought as cool colorants. Through appropriate doping two pigments Ce-Pr-Mo and Ce-Pr-Fe have been developed to offer a reddish brown and reddish orange color, respectively. These pigments have been characterized and found to be highly crystalline with an average size of 300 nm. A shift in band gap energy from 2.21 to 2.18 eV has been observed when Li{sub 2}CO{sub 3} was used as a mineralizer. Scanning electron microscope-energy dispersive X-ray analysis (SEM-EDAX) measurement indicate a uniform grind shape and distribution of metal ion, with over 65% reflectance in the NIR region, these pigments can well serve as cool colorants. (author)

  5. High altitude medicine education in China: exploring a new medical education reform.

    Science.gov (United States)

    Luo, Yongjun; Luo, Rong; Li, Weiming; Huang, Jianjun; Zhou, Qiquan; Gao, Yuqi

    2012-03-01

    China has the largest plateau in the world, which includes the whole of Tibet, part of Qinghai, Xinjiang, Yunnan, and Sichuan. The plateau area is about 257.2×10(4) km(2), which accounts for about 26.8% of the total area of China. According to data collected in 2006, approximately twelve million people were living at high altitudes, between 2200 to 5200 m high, on the Qinghai-Tibetan Plateau. Therefore, there is a need for medical workers who are trained to treat individuals living at high altitudes. To train undergraduates in high altitude medicine, the College of High Altitude Military Medicine was set up at the Third Military Medical University (TMMU) in Chongqing in 1999. This is the only school to teach high altitude medicine in China. Students at TMMU study natural and social sciences, basic medical sciences, clinical medical sciences, and high altitude medicine. In their 5(th) year, students work as interns at the General Hospital of Tibet Military Command in Lhasa for 3 months, where they receive on-site teaching. The method of on-site teaching is an innovative approach for training in high altitude medicine for undergraduates. Three improvements were implemented during the on-site teaching component of the training program: (1) standardization of the learning progress; (2) integration of formal knowledge with clinical experience; and (3) coaching students to develop habits of inquiry and to engage in ongoing self-improvement to set the stage for lifelong learning. Since the establishment of the innovative training methods in 2001, six classes of high altitude medicine undergraduates, who received on-site teaching, have graduated and achieved encouraging results. This evidence shows that on-site teaching needs to be used more widely in high altitude medicine education.

  6. Accuracy of Handheld Blood Glucose Meters at High Altitude

    NARCIS (Netherlands)

    de Mol, Pieter; Krabbe, Hans G.; de Vries, Suzanna T.; Fokkert, Marion J.; Dikkeschei, Bert D.; Rienks, Rienk; Bilo, Karin M.; Bilo, Henk J. G.

    2010-01-01

    Background: Due to increasing numbers of people with diabetes taking part in extreme sports (e. g., high-altitude trekking), reliable handheld blood glucose meters (BGMs) are necessary. Accurate blood glucose measurement under extreme conditions is paramount for safe recreation at altitude. Prior

  7. Outdoor Activity and High Altitude Exposure During Pregnancy: A Survey of 459 Pregnancies.

    Science.gov (United States)

    Keyes, Linda E; Hackett, Peter H; Luks, Andrew M

    2016-06-01

    To evaluate whether women engage in outdoor activities and high altitude travel during pregnancy; the health care advice received regarding high altitude during pregnancy; and the association between high altitude exposure and self-reported pregnancy complications. An online survey of women with at least 1 pregnancy distributed on websites and e-mail lists targeting mothers and/or mountain activities. Outcome measures were outdoor activities during pregnancy, high altitude (>2440 m) exposure during pregnancy, and pregnancy and perinatal complications. Hiking, running, and swimming were the most common activities performed during pregnancy. Women traveled to high altitude in over half of the pregnancies (244/459), and most did not receive counseling regarding altitude (355, 77%), although a small proportion (14, 3%) were told not to go above 2440 m. Rates of miscarriage and most other complications were similar between pregnancies with and without travel above 2440 m. Pregnancies with high altitude exposure were more likely to have preterm labor (odds ratio [OR] 2.3; 95% CI 0.97-5.4; P = .05). Babies born to women who went to high altitude during pregnancy were more likely to need oxygen at birth (OR 2.34; 95% CI 1.04-5.26; P sports and travel to high altitude have a low rate of complications. Given the limitations of our data, further research is necessary on the risks associated with high altitude travel and physical activity and how these apply to the general population. Copyright © 2016 Wilderness Medical Society. Published by Elsevier Inc. All rights reserved.

  8. HIGH ALTITUDES EFFECTS ON HEMATOLOGIC BLOOD PARAMETERS

    Directory of Open Access Journals (Sweden)

    Hasim Rushiti

    2015-05-01

    Full Text Available The approach and the objective of this experiment are consistent with the determination of changes of blood parameters after the stay of the students at an altitude of 1800-2300 meters, for a ten-day long ski course. In this paper are included a total of 64 students of the Faculty of Sport Sciences in Prishtina, of the age group of 19-25 (the average age is 21. All students previously have undergone a medical check for TA, arterial pulse and respiratory rate. In particular, the health situation is of subjects was examined, then, all students, at the same time, gave blood for analysis. In this experiment, three main hematologic parameters were taken in consideration: such as hemoglobin, hematocrit and red blood cells. The same analyses were carried out after the 10-day stay at a high altitude. The results of the experiment have shown significant changes after the ten-day stay at high altitude, despite the previous results that show changes only after the twenty-day stay in such elevations.

  9. [Physiological aspects of altitude training and the use of altitude simulators].

    Science.gov (United States)

    Ranković, Goran; Radovanović, Dragan

    2005-01-01

    Altitude training in various forms is widely practiced by athletes and coaches in an attempt to improve sea level endurance. Training at high altitude may improve performance at sea level through altitude acclimatisation, which improves oxygen transport and/or utilisation, or through hypoxia, which intensifies the training stimulus. This basic physiological aspect allows three training modalities: live high and train high (classic high-altitude training), live low and train high (training through hypoxia), and live high and train low (the new trend). In an effort to reduce the financial and logistical challenges of travelling to high-altitude training sites, scientists and manufactures have developed artificial high-altitude environments, which simulate the hypoxic conditions of moderate altitude (2000-3000 meters). Endurance athletes from many sports have recently started using nitrogen environments, or hypoxic rooms and tents as part of their altitude training programmes. The results of controlled studies on these modalities of high-altitude training, their practical approach, and ethics are summarised.

  10. Physiological aspects of altitude training and the use of altitude simulators

    Directory of Open Access Journals (Sweden)

    Ranković Goran

    2005-01-01

    Full Text Available Altitude training in various forms is widely practiced by athletes and coaches in an attempt to improve sea level endurance. Training at high altitude may improve performance at sea level through altitude acclimatization, which improves oxygen transport and/or utilization, or through hypoxia, which intensifies the training stimulus. This basic physiological aspect allows three training modalities: live high and train high (classic high-altitude training, live low and train high (training through hypoxia, and live high and train low (the new trend. In an effort to reduce the financial and logistical challenges of traveling to high-altitude training sites, scientists and manufactures have developed artificial high-altitude environments, which simulate the hypoxic conditions of moderate altitude (2000-3000 meters. Endurance athletes from many sports have recently started using nitrogen environments, or hypoxic rooms and tents as part of their altitude training programmes. The results of controlled studies on these modalities of high-altitude training, their practical approach, and ethics are summarized.

  11. Low-resolution ship detection from high-altitude aerial images

    Science.gov (United States)

    Qi, Shengxiang; Wu, Jianmin; Zhou, Qing; Kang, Minyang

    2018-02-01

    Ship detection from optical images taken by high-altitude aircrafts such as unmanned long-endurance airships and unmanned aerial vehicles has broad applications in marine fishery management, ship monitoring and vessel salvage. However, the major challenge is the limited capability of information processing on unmanned high-altitude platforms. Furthermore, in order to guarantee the wide detection range, unmanned aircrafts generally cruise at high altitudes, resulting in imagery with low-resolution targets and strong clutters suffered by heavy clouds. In this paper, we propose a low-resolution ship detection method to extract ships from these high-altitude optical images. Inspired by a recent research on visual saliency detection indicating that small salient signals could be well detected by a gradient enhancement operation combined with Gaussian smoothing, we propose the facet kernel filtering to rapidly suppress cluttered backgrounds and delineate candidate target regions from the sea surface. Then, the principal component analysis (PCA) is used to compute the orientation of the target axis, followed by a simplified histogram of oriented gradient (HOG) descriptor to characterize the ship shape property. Finally, support vector machine (SVM) is applied to discriminate real targets and false alarms. Experimental results show that the proposed method actually has high efficiency in low-resolution ship detection.

  12. Structural and Visible-Near Infrared Optical Properties of Cr-Doped TiO2 for Colored Cool Pigments

    Science.gov (United States)

    Yuan, Le; Weng, Xiaolong; Zhou, Ming; Zhang, Qingyong; Deng, Longjiang

    2017-11-01

    Chromium-doped TiO2 pigments were synthesized via a solid-state reaction method and studied with X-ray diffraction, SEM, XPS, and UV-VIS-NIR reflectance spectroscopy. The incorporation of Cr3+ accelerates the transition from the anatase phase to the rutile phase and compresses the crystal lattice. Moreover, the particle morphology, energy gap, and reflectance spectrum of Cr-doped TiO2 pigments is affected by the crystal structure and doping concentration. For the rutile samples, some of the Cr3+ ions are oxidized to Cr4+ after sintering at a high temperature, which leads to a strong near-infrared absorption band due to the 3A2 → 3 T1 electric dipole-allowed transitions of Cr4+. And the decrease of the band gap causes an obvious redshift of the optical absorption edges as the doping concentration increases. Thus, the VIS and near-infrared average reflectance of the rutile Ti1 - x Cr x O2 sample decrease by 60.2 and 58%, respectively, when the Cr content increases to x = 0.0375. Meanwhile, the color changes to black brown. However, for the anatase Ti1 - x Cr x O2 pigments, only the VIS reflection spectrum is inhibited by forming some characteristic visible light absorption peaks of Cr3+. The morphology, band gap, and NIR reflectance are not significantly affected. Finally, a Cr-doped anatase TiO2 pigment with a brownish-yellow color and 90% near-infrared reflectance can be obtained.

  13. Fatalities in high altitude mountaineering: a review of quantitative risk estimates.

    Science.gov (United States)

    Weinbruch, Stephan; Nordby, Karl-Christian

    2013-12-01

    Quantitative estimates for mortality in high altitude mountaineering are reviewed. Special emphasis is placed on the heterogeneity of the risk estimates and on confounding. Crude estimates for mortality are on the order of 1/1000 to 40/1000 persons above base camp, for both expedition members and high altitude porters. High altitude porters have mostly a lower risk than expedition members (risk ratio for all Nepalese peaks requiring an expedition permit: 0.73; 95 % confidence interval 0.59-0.89). The summit bid is generally the most dangerous part of an expedition for members, whereas most high altitude porters die during route preparation. On 8000 m peaks, the mortality during descent from summit varies between 4/1000 and 134/1000 summiteers (members plus porters). The risk estimates are confounded by human and environmental factors. Information on confounding by gender and age is contradictory and requires further work. There are indications for safety segregation of men and women, with women being more risk averse than men. Citizenship appears to be a significant confounder. Prior high altitude mountaineering experience in Nepal has no protective effect. Commercial expeditions in the Nepalese Himalayas have a lower mortality than traditional expeditions, though after controlling for confounding, the difference is not statistically significant. The overall mortality is increasing with increasing peak altitude for expedition members but not for high altitude porters. In the Nepalese Himalayas and in Alaska, a significant decrease of mortality with calendar year was observed. A few suggestions for further work are made at the end of the article.

  14. A subjective evaluation of high-chroma color with wide color-gamut display

    Science.gov (United States)

    Kishimoto, Junko; Yamaguchi, Masahiro; Ohyama, Nagaaki

    2009-01-01

    Displays tends to expand its color gamut, such as multi-primary color display, Adobe RGB and so on. Therefore displays got possible to display high chroma colors. However sometimes, we feel unnatural some for the image which only expanded chroma. Appropriate gamut mapping method to expand color gamut is not proposed very much. We are attempting preferred expanded color reproduction on wide color gamut display utilizing high chroma colors effectively. As a first step, we have conducted an experiment to investigate the psychological effect of color schemes including highly saturated colors. We used the six-primary-color projector that we have developed for the presentation of test colors. The six-primary-color projector's gamut volume in CIELAB space is about 1.8 times larger than the normal RGB projector. We conducted a subjective evaluation experiment using the SD (Semantic Differential) technique to find the quantitative psychological effect of high chroma colors.

  15. The use of color infrared imagery for the study of marsh buggy tracks

    Science.gov (United States)

    Whitehurst, C. A.; Doiron, L. N.

    1974-01-01

    Color infrared imagery is used to determine the location of buggy routes and to quantify the extent of tracks in a selected area where the marsh is seriously dissected. The imagery is used to show successive stages of destruction. It is recommended that alternate routes be identified in the operating area to eliminate continuous use of the same route and facilitate faster revegetation.

  16. Increased insulin requirements during exercise at very high altitude in type 1 diabetes

    NARCIS (Netherlands)

    de Mol, Pieter; de Vries, Suzanna T.; de Koning, Eelco J. P.; Gans, Rijk O. B.; Tack, Cees J.; Bilo, Henk J. G.

    OBJECTIVE-Safe, very high altitude trekking in subjects with type 1 diabetes requires understanding of glucose regulation at high altitude. We investigated insulin requirements, energy expenditure, and glucose levels at very high altitude in relation to acute mountain sickness (AMS) symptoms in

  17. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Ghazni1 mineral district in Afghanistan: Chapter DD in Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.

    2014-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Ghazni1 mineral district, which has spectral reflectance anomalies indicative of clay, aluminum, gold, silver, mercury, and sulfur deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420-500 nanometer, nm), green (520-600 nm), red (610-690 nm), and near-infrared (760-890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520-770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency ((c)JAXA, 2008, 2009), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such

  18. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the South Helmand mineral district in Afghanistan: Chapter O in Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.; Cagney, Laura E.

    2013-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the South Helmand mineral district, which has travertine deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420–500 nanometer, nm), green (520–600 nm), red (610–690 nm), and near-infrared (760–890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520–770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency (©JAXA, 2008, 2010), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be recreated from this DS. As such

  19. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Ghazni2 mineral district in Afghanistan: Chapter EE in Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.

    2014-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Ghazni2 mineral district, which has spectral reflectance anomalies indicative of gold, mercury, and sulfur deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420-500 nanometer, nm), green (520-600 nm), red (610-690 nm), and near-infrared (760-890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520-770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency ((c)JAXA, 2008, 2009), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image

  20. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the North Takhar mineral district in Afghanistan: Chapter D in Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.; Cagney, Laura E.

    2012-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the North Takhar mineral district, which has placer gold deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420–500 nanometer, nm), green (520–600 nm), red (610–690 nm), and near-infrared (760–890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520–770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency (©JAXA,2006,2008), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be recreated from this DS. As such

  1. Mitochondrial function in human skeletal muscle following high-altitude exposure

    DEFF Research Database (Denmark)

    Jacobs, Robert A; Boushel, Robert; Wright-Paradis, Cynthia

    2013-01-01

    Studies regarding mitochondrial modifications in human skeletal muscle following acclimatization to high altitude are conflicting, and these inconsistencies may be due to the prevalence of representing mitochondrial function through static and isolated measurements of specific mitochondrial...... characteristics. The aim of this study, therefore, was to investigate mitochondrial function in response to high-altitude acclimatization through measurements of respiratory control in the vastus lateralis muscle. Skeletal muscle biopsies were obtained from 10 lowland natives prior to and again after a total of 9......-11 days of exposure to 4559 m. High-resolution respirometry was performed on the muscle samples to compare respiratory chain function and respiratory capacities. Respirometric analysis revealed that mitochondrial function was largely unaffected, because high-altitude exposure did not affect the capacity...

  2. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Kandahar mineral district in Afghanistan: Chapter Z in Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.

    2013-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Kandahar mineral district, which has bauxite deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420-500 nanometer, nm), green (520-600 nm), red (610-690 nm), and near-infrared (760-890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520-770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency ((c)JAXA,2006,2007,2008), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be recreated from this DS. As such, the DS

  3. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Farah mineral district in Afghanistan: Chapter FF in Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.

    2014-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Farah mineral district, which has spectral reflectance anomalies indicative of copper, zinc, lead, silver, and gold deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420-500 nanometer, nm), green (520-600 nm), red (610-690 nm), and near-infrared (760-890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520-770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency ((c)JAXA, 2007, 2008, 2010), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that

  4. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Kunduz mineral district in Afghanistan: Chapter S in Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.; Arko, Scott A.; Harbin, Michelle L.

    2013-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Kunduz mineral district, which has celestite deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420–500 nanometer, nm), green (520–600 nm), red (610–690 nm), and near-infrared (760–890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520–770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency (©JAXA,2007,2008,2009), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be recreated from this DS. As such, the

  5. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Zarkashan mineral district in Afghanistan: Chapter G in Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.; Cagney, Laura E.

    2012-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Zarkashan mineral district, which has copper and gold deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420–500 nanometer, nm), green (520–600 nm), red (610–690 nm), and near-infrared (760–890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520–770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency (©JAXA,2006,2007, 2008), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be recreated from this DS. As

  6. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Dudkash mineral district in Afghanistan: Chapter R in Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.; Arko, Scott A.; Harbin, Michelle L.

    2013-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Dudkash mineral district, which has industrial mineral deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420–500 nanometer, nm), green (520–600 nm), red (610–690 nm), and near-infrared (760–890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520–770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency (©JAXA,2006,2007,2008,2009), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be recreated from this DS

  7. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Khanneshin mineral district in Afghanistan: Chapter A in Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.; Cagney, Laura E.; Arko, Scott A.; Harbin, Michelle L.

    2012-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Khanneshin mineral district, which has uranium, thorium, rare-earth-element, and apatite deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420-500 nanometer, nm), green (520-600 nm), red (610-690 nm), and near-infrared (760-890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520-770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency (©JAXA,2007,2008,2010), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be

  8. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Aynak mineral district in Afghanistan: Chapter E in Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.; Cagney, Laura E.; Arko, Scott A.; Harbin, Michelle L.

    2012-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Aynak mineral district, which has copper deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420–500 nanometer, nm), green (520–600 nm), red (610–690 nm), and near-infrared (760–890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520–770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency ((c)JAXA,2008,2010), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be recreated from this DS. As such, the DS

  9. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Nalbandon mineral district in Afghanistan: Chapter L in Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.; Cagney, Laura E.

    2013-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Nalbandon mineral district, which has lead and zinc deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420–500 nanometer, nm), green (520–600 nm), red (610–690 nm), and near-infrared (760–890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520–770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency (©JAXA, 2007, 2008, 2010), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be recreated from this DS. As

  10. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Kundalyan mineral district in Afghanistan: Chapter H in Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.; Cagney, Laura E.; Arko, Scott A.; Harbin, Michelle L.

    2012-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Kundalyan mineral district, which has porphyry copper and gold deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420–500 nanometer, nm), green (520–600 nm), red (610–690 nm), and near-infrared (760–890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520–770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency (©JAXA,2008), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be recreated from this DS. As

  11. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Herat mineral district in Afghanistan: Chapter T in Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.; Arko, Scott A.; Harbin, Michelle L.

    2013-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Herat mineral district, which has barium and limestone deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420–500 nanometer, nm), green (520–600 nm), red (610–690 nm), and near-infrared (760–890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520–770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency (©JAXA,2007,2008,2009), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be recreated from this DS. As

  12. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Tourmaline mineral district in Afghanistan: Chapter J in Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.; Cagney, Laura E.; Arko, Scott A.; Harbin, Michelle L.

    2012-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Tourmaline mineral district, which has tin deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420–500 nanometer, nm), green (520–600 nm), red (610–690 nm), and near-infrared (760–890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520–770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency (©JAXA,2008), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be recreated from this DS. As such, the DS products

  13. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Badakhshan mineral district in Afghanistan: Chapter F in Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.; Arko, Scott A.; Harbin, Michelle L.

    2012-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Badakhshan mineral district, which has gold deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420-500 nanometer, nm), green (520-600 nm), red (610-690 nm), and near-infrared (760-890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520-770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency ((c)JAXA,2007,2008), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be recreated from this DS. As such, the DS products

  14. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Balkhab mineral district in Afghanistan: Chapter B in Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.; Cagney, Laura E.

    2012-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Balkhab mineral district, which has copper deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420-500 nanometer, nm), green (520-600 nm), red (610-690 nm), and near-infrared (760-890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520-770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency (©JAXA,2007,2008), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be recreated from this DS. As such, the DS products match

  15. Reduced oxygen at high altitude limits maximum size.

    Science.gov (United States)

    Peck, L S; Chapelle, G

    2003-11-07

    The trend towards large size in marine animals with latitude, and the existence of giant marine species in polar regions have long been recognized, but remained enigmatic until a recent study showed it to be an effect of increased oxygen availability in sea water of a low temperature. The effect was apparent in data from 12 sites worldwide because of variations in water oxygen content controlled by differences in temperature and salinity. Another major physical factor affecting oxygen content in aquatic environments is reduced pressure at high altitude. Suitable data from high-altitude sites are very scarce. However, an exceptionally rich crustacean collection, which remains largely undescribed, was obtained by the British 1937 expedition from Lake Titicaca on the border between Peru and Bolivia in the Andes at an altitude of 3809 m. We show that in Lake Titicaca the maximum length of amphipods is 2-4 times smaller than other low-salinity sites (Caspian Sea and Lake Baikal).

  16. High-altitude haematology: Quechua-Aymara comparisons.

    Science.gov (United States)

    Arnaud, J; Quilici, J C; Rivière, G

    1981-01-01

    Haematological studies have been carried out at various altitudes between 450 m and 4800 m, on two separate human groups (Quechuas and Aymaras) living in South America. Changes in the haematological parameters do not develop linearly in relation to the attitude. Th impact of chronic hypoxia on erythropoiesis is greater above 3000 m. The haemogram varies quantitatively and not qualitatively (mean corpuscular volume and mean haemoglobin concentration remain constant). The haematological study also reveals the greater adaptability to high altitude of the Aymaras, an adaptability characterized by an increase in red cell count and concentration and a decrease in red cell volume. The adaptative phenomena observed in the Quechuas are reversible, whereas they persist in the Aymaras when they migrate to the lowlands (450 m).

  17. The radiation protection problems of high altitude and space flight

    International Nuclear Information System (INIS)

    Fry, R.J.M.

    1993-01-01

    This paper considers the radiation environment in aircraft at high altitudes and spacecraft in low earth orbit and in deep space and the factors that influence the dose equivalents. Altitude, latitude and solar cycle are the major influences for flights below the radiation belts. In deep space, solar cycle and the occurrence of solar particle events are the factors of influence. The major radiation effects of concern are cancer and infertility in males. In high altitude aircraft the radiation consists mainly of protons and neutrons, with neutrons contributing about half the equivalent dose. The average dose rate at altitudes of transcontinental flights that approach the polar regions are greater by a factor of about 2.5 than on routes at low latitudes. Current estimates of does to air crews suggest they are well within the ICRP (1990) recommended dose limits for radiation workers

  18. Risk Stratification for Athletes and Adventurers in High-Altitude Environments: Recommendations for Preparticipation Evaluation.

    Science.gov (United States)

    Campbell, Aaron D; McIntosh, Scott E; Nyberg, Andy; Powell, Amy P; Schoene, Robert B; Hackett, Peter

    2015-12-01

    High-altitude athletes and adventurers face a number of environmental and medical risks. Clinicians often advise participants or guiding agencies before or during these experiences. Preparticipation evaluation (PPE) has the potential to reduce risk of high-altitude illnesses in athletes and adventurers. Specific conditions susceptible to high-altitude exacerbation also important to evaluate include cardiovascular and lung diseases. Recommendations by which to counsel individuals before participation in altitude sports and adventures are few and of limited focus. We reviewed the literature, collected expert opinion, and augmented principles of a traditional sport PPE to accommodate the high-altitude wilderness athlete/adventurer. We present our findings with specific recommendations on risk stratification during a PPE for the high-altitude athlete/adventurer. Copyright © 2015. Published by Elsevier Inc.

  19. Nasal variation in relation to high-altitude adaptations among Tibetans and Andeans.

    Science.gov (United States)

    Butaric, Lauren N; Klocke, Ross P

    2018-05-01

    High-altitude (>2500 m) populations face several pressures, including hypoxia and cold-dry air, resulting in greater respiratory demand to obtain more oxygen and condition inspired air. While cardiovascular and pulmonary adaptations to high-altitude hypoxia have been extensively studied, adaptations of upper-respiratory structures, e.g., nasal cavity, remain untested. This study investigates whether nasal morphology presents adaptations to hypoxic (larger noses) and/or cold-dry (tall/narrow noses) conditions among high-altitude samples. CT scans of two high- and four low-altitude samples from diverse climates were collected (n = 130): high-altitude Tibetans and Peruvians; low-altitude Peruvians, Southern Chinese (temperate), Mongolian-Buriats (cold-dry), and Southeast Asians (hot-wet). Facial and nasal distances were calculated from 3D landmarks placed on digitally-modeled crania. Temperature, precipitation, and barometric pressure data were also obtained. Principal components analysis and analyses of variance primarily indicate size-related differences among the cold-dry (Mongolian-Buriats) and hot-wet (Southeast Asians) adapted groups. Two-block partial least squares (PLS) analysis show weak relationships between size-standardized nasal dimensions and environmental variables. However, among PLS1 (85.90% of covariance), Tibetans display relatively larger nasal cavities related to lower temperatures and barometric pressure; regression analyses also indicate high-altitude Tibetans possess relatively larger internal nasal breadths and heights for their facial size. Overall, nasal differences relate to climate among the cold-dry and hot-wet groups. Specific nasal adaptations were not identified among either Peruvian group, perhaps due to their relatively recent migration history and population structure. However, high-altitude Tibetans seem to exhibit a compromise in nasal morphology, serving in increased oxygen uptake, and air-conditioning processes. © 2018

  20. Mast cells in the human lung at high altitude

    Science.gov (United States)

    Heath, Donald

    1992-12-01

    Mast cell densities in the lung were measured in five native highlanders of La Paz (3600 m) and in one lowlander dying from high-altitude pulmonary oedema (HAPO) at 3440 m. Two of the highlanders were mestizos with normal pulmonary arteries and the others were Aymara Indians with muscular remodelling of their pulmonary vasculature. The aim of the investigation was to determine if accumulation of mast cells in the lung at high altitude (HA) is related to alveolar hypoxia alone, to a combination of hypoxia and muscularization of the pulmonary arterial tree, or to oedema of the lung. The lungs of four lowlanders were used as normoxic controls. The results showed that the mast cell density of the two Mestizos was in the normal range of lowlanders (0.6-8.8 cells/mm2). In the Aymara Indians the mast cell counts were raised (25.6-26.0 cells/mm2). In the lowlander dying from HAPO the mast cell count was greatly raised to 70.1 cells/mm2 lung tissue. The results show that in native highlanders an accumulation of mast cells in the lung is not related to hypoxia alone but to a combination of hypoxia and muscular remodelling of the pulmonary arteries. However, the most potent cause of increased mast cell density in the lung at high altitude appears to be high-altitude pulmonary oedema.

  1. Air Quality Standards for Particulate Matter (PM) at high altitude cities

    International Nuclear Information System (INIS)

    Bravo Alvarez, H.; Sosa Echeverria, R.; Sanchez Alvarez, P.; Krupa, S.

    2013-01-01

    The Air Quality Standards for Particulate Matter (PM) at high altitude urban areas in different countries, must consider the pressure and temperature due to the effect that these parameters have on the breath volume. This paper shows the importance to correct Air Quality Standards for PM considering pressure and temperature at different altitudes. Specific factors were suggested to convert the information concerning PM, from local to standard conditions, and adjust the Air Quality Standards for different high altitudes cities. The correction factors ranged from: 1.03 for Santiago de Chile to 1.47 for El Alto Bolivia. Other cities in this study include: Mexico City, México; La Paz, Bolivia; Bogota, Cali and Medellin, Colombia; Quito, Ecuador and Cuzco, Peru. If these corrections are not considered, the atmospheric concentrations will be underestimated. - Highlights: ► AQS for particulate matter concentrations adjusted by pressure and temperature. ► Particulate matter concentrations can be underestimated in high altitude Cities. ► Particulate matter concentrations must be compared under the same conditions. - In order to compare high altitude atmospheric PM concentrations with AQS, one must consider T and P of the sampling site.

  2. Circulatory adaptation to long-term high altitude exposure in Aymaras and Caucasians.

    Science.gov (United States)

    Stuber, Thomas; Scherrer, Urs

    2010-01-01

    About 30 million people live above 2500 m in the Andean Mountains of South America. Among them are 5.5 million Aymaras, an ethnic group with its own language, living on the altiplano of Bolivia, Peru, and northern Chile at altitudes of up to 4400 m. In this high altitude region traces of human population go back for more than 2000 years with constant evolutionary pressure on its residents for genetic adaptation to high altitude. Aymaras as the assumed direct descendents of the ancient cultures living in this region were the focus of much research interest during the last decades and several distinctive adaptation patterns to life at high altitude have been described in this ethnic group. The aim of this article was to review the physiology and pathophysiology of circulatory adaptation and maladaptation to longtime altitude exposure in Aymaras and Caucasians.

  3. Cerebral venous system and anatomical predisposition to high-altitude headache

    NARCIS (Netherlands)

    Wilson, Mark H.; Davagnanam, Indran; Holland, Graeme; Dattani, Raj S.; Tamm, Alexander; Hirani, Shashivadan P.; Kolfschoten, Nicky; Strycharczuk, Lisa; Green, Cathy; Thornton, John S.; Wright, Alex; Edsell, Mark; Kitchen, Neil D.; Sharp, David J.; Ham, Timothy E.; Murray, Andrew; Holloway, Cameron J.; Clarke, Kieran; Grocott, Mike P. W.; Montgomery, Hugh; Imray, Chris; Ahuja, V.; Aref-Adib, G.; Burnham, R.; Chisholm, A.; Clarke, K.; Coates, D.; Coates, M.; Cook, D.; Cox, M.; Dhillon, S.; Dougall, C.; Doyle, P.; Duncan, P.; Edsell, M.; Edwards, L.; Evans, L.; Gardiner, P.; Grocott, M.; Gunning, P.; Hart, N.; Harrington, J.; Harvey, J.; Holloway, C.; Howard, D.; Hurlbut, D.; Imray, C.; Ince, C.; Jonas, M.; van der Kaaij, J.

    2013-01-01

    As inspired oxygen availability falls with ascent to altitude, some individuals develop high-altitude headache (HAH). We postulated that HAH results when hypoxia-associated increases in cerebral blood flow occur in the context of restricted venous drainage, and is worsened when cerebral compliance

  4. Training-dependent cognitive advantage is suppressed at high altitude.

    Science.gov (United States)

    Li, Peng; Zhang, Gang; You, Hai-Yan; Zheng, Ran; Gao, Yu-Qi

    2012-06-25

    Ascent to high altitude is associated with decreases in cognitive function and work performance as a result of hypoxia. Some workers with special jobs typically undergo intensive mental training because they are expected to be agile, stable and error-free in their job performance. The purpose of this study was to determine the risk to cognitive function acquired from training following hypoxic exposure. The results of WHO neurobehavioral core tests battery (WHO-NCTB) and Raven's standard progressive matrices (RSPM) tests of a group of 54 highly trained military operators were compared with those of 51 non-trained ordinary people and were investigated at sea level and on the fifth day after arrival at high altitudes (3900m). Meanwhile, the plasma levels of brain-derived neurotrophic factor (BDNF), interleukin 1β (IL-1β) and vascular endothelial growth factor (VEGF) were examined. The result showed that at sea level, the trained group exhibited significantly better performance on neurobehavioral and RSPM tests. At high altitude, both groups had decreased accuracy in most cognitive tests and took longer to finish them. More importantly, the highly trained subjects showed more substantial declines than the non-trained subjects in visual reaction accuracy, auditory reaction speed, digit symbol scores, ability to report correct dots in a pursuit aiming test and total RSPM scores. This means that the training-dependent cognitive advantages in these areas were suppressed at high altitudes. The above phenomenon maybe associated with decreased BDNF and elevated inflammatory factor during hypoxia, and other mechanisms could not be excluded. Copyright © 2012 Elsevier Inc. All rights reserved.

  5. Study of the application of ERTS-A imagery to fracture-related mine safety hazards in the coal mining industry

    Science.gov (United States)

    Wier, C. E.; Wobber, F. J. (Principal Investigator); Russell, O. R.; Amato, R. V.

    1972-01-01

    The author has identified the following significant results. Various data compilation and analysis activities in support of ERTS-1 imagery interpretation are in progress or are completed. These include the compilation of mine accident data, areas of mine roof instability and the analysis of high altitude color infrared photography and low altitude color and color infrared photography which was acquired by NASA in support of the project. The photography reveals that many fracture lineaments are detectable through a varied thickness of glacial till. These data will be compiled on a series of 1:250,000 scale base maps and evaluated for a correlation between fracture zones and mine accidents and rooffalls. Due to high occurrence of cloud cover in the project area and to the delay in imagery shipments, little progress has been made in the analysis of ERTS-1 imagery.

  6. Are macroinvertebrates in high altitude streams affected by oxygen deficiency?

    DEFF Research Database (Denmark)

    Jacobsen, Dean; Rostgaard, S.; Vásconez, J. J.

    2003-01-01

    1. The solubility of oxygen in water increases with decreasing temperature. This has led to a general perception of cold, high mountain streams as more oxygen rich than warmer lowland streams, and that macroinvertebrates inhabiting high altitude streams have had no need to adapt to critical oxygen...... conditions. However, this fails to take into account that oxygen solubility declines with decreasing atmospheric pressure, which may be of importance at high altitudes. 2. Based on samples of macroinvertebrate benthos and in situ measurements of respiratory oxygen demand of macroinvertebrates in small...... the mean weight-specific respiratory rate of macroinvertebrates declined by only 50%, from 400 to 3800 m. We suggest that this disproportionately large gap between availability and demand of oxygen at high altitudes may imply a potential oxygen deficiency for the fauna, and we discuss how oxygen deficiency...

  7. Hyperbaric oxygen therapy ameliorates acute brain injury after porcine intracerebral hemorrhage at high altitude.

    Science.gov (United States)

    Zhu, Hai-tao; Bian, Chen; Yuan, Ji-chao; Liao, Xiao-jun; Liu, Wei; Zhu, Gang; Feng, Hua; Lin, Jiang-kai

    2015-06-15

    Intracerebral hemorrhage (ICH) at high altitude is not well understood to date. This study investigates the effects of high altitude on ICH, and examines the acute neuroprotection of hyperbaric oxygen (HBO) therapy against high-altitude ICH. Minipigs were placed in a hypobaric chamber for 72 h before the operation. ICH was induced by an infusion of autologous arterial blood (3 ml) into the right basal ganglia. Animals in the high-altitude ICH group received HBO therapy (2.5 ATA for 60 min) 30 min after ICH. Blood gas, blood glucose and brain tissue oxygen partial pressure (PbtO2) were monitored continuously for animals from all groups, as were microdialysis products including glucose, lactate, pyruvate and glutamate in perihematomal tissue from 3 to 12 h post-ICH. High-altitude ICH animals showed significantly lower PbtO2, higher lactate/pyruvate ratio (LPR) and glutamate levels than low-altitude ICH animals. More severe neurological deficits, brain edema and neuronal damage were also observed in high-altitude ICH. After HBO therapy, PbtO2 was significantly increased and LPR and glutamate levels were significantly decreased. Brain edema, neurological deficits and neuronal damage were also ameliorated. The data suggested a more serious disturbance of tissue oxygenation and cerebral metabolism in the acute stage after ICH at high altitude. Early HBO treatment reduced acute brain injury, perhaps through a mechanism involving the amelioration of the derangement of cerebral oxygenation and metabolism following high-altitude ICH.

  8. Frequency modulation of high-order harmonic generation in an orthogonally polarized two-color laser field.

    Science.gov (United States)

    Li, Guicun; Zheng, Yinghui; Ge, Xiaochun; Zeng, Zhinan; Li, Ruxin

    2016-08-08

    We have experimentally investigated the frequency modulation of high-order harmonics in an orthogonally polarized two-color laser field consisting of a mid-infrared 1800nm fundamental pulse and its second harmonic pulse. It is demonstrated that the high harmonic spectra can be fine-tuned as we slightly change the relative delay of the two-color laser pulses. By analyzing the relative frequency shift of each harmonic at different two-color delays, the nonadiabatic spectral shift induced by the rapid variation of the intensity-dependent intrinsic dipole phase can be distinguished from the blueshift induced by the change of the refractive index during self-phase modulation (SPM). Our comprehensive analysis shows that the frequency modulation pattern is a reflection of the average emission time of high-order harmonic generation (HHG), thus offering a simple method to fine-tune the spectra of the harmonics on a sub-cycle time scale.

  9. Cold induced peripheral vasodilation at high altitudes- a field study

    NARCIS (Netherlands)

    Daanen, H.A.M.; Ruiten, H.J.A. van

    2000-01-01

    A significant reduction in cold-induced vasodilation (CIVD) is observed at high altitudes. No agreement is found in the literature about acclimatization effects on CIVD. Two studies were performed to investigate the effect of altitude acclimatization on CIVD. In the first study 13 male subjects

  10. Control of breathing and the circulation in high-altitude mammals and birds.

    Science.gov (United States)

    Ivy, Catherine M; Scott, Graham R

    2015-08-01

    Hypoxia is an unremitting stressor at high altitudes that places a premium on oxygen transport by the respiratory and cardiovascular systems. Phenotypic plasticity and genotypic adaptation at various steps in the O2 cascade could help offset the effects of hypoxia on cellular O2 supply in high-altitude natives. In this review, we will discuss the unique mechanisms by which ventilation, cardiac output, and blood flow are controlled in high-altitude mammals and birds. Acclimatization to high altitudes leads to some changes in respiratory and cardiovascular control that increase O2 transport in hypoxia (e.g., ventilatory acclimatization to hypoxia). However, acclimatization or development in hypoxia can also modify cardiorespiratory control in ways that are maladaptive for O2 transport. Hypoxia responses that arose as short-term solutions to O2 deprivation (e.g., peripheral vasoconstriction) or regional variation in O2 levels in the lungs (i.e., hypoxic pulmonary vasoconstriction) are detrimental at in chronic high-altitude hypoxia. Evolved changes in cardiorespiratory control have arisen in many high-altitude taxa, including increases in effective ventilation, attenuation of hypoxic pulmonary vasoconstriction, and changes in catecholamine sensitivity of the heart and systemic vasculature. Parallel evolution of some of these changes in independent highland lineages supports their adaptive significance. Much less is known about the genomic bases and potential interactive effects of adaptation, acclimatization, developmental plasticity, and trans-generational epigenetic transfer on cardiorespiratory control. Future work to understand these various influences on breathing and circulation in high-altitude natives will help elucidate how complex physiological systems can be pushed to their limits to maintain cellular function in hypoxia. Copyright © 2014 Elsevier Inc. All rights reserved.

  11. EFFECT OF HIGH ALTITUDE ON ERECTILE FUNCTION IN OTHERWISE HEALTHY INDIVIDUALS

    Directory of Open Access Journals (Sweden)

    Usama Bin Zubair

    2016-06-01

    Full Text Available Objective: To determine the effect of high altitude on Erectile function in otherwise healthy individuals and associated socio demographic factors. Study Design: Cross sectional descriptive study. Place and Duration of Study: January 2014 to March 2014 at Goma, Siachin. Material and Methods: One hundred & twenty two married male subjects living at an altitude of more than 15000 feet for more than 3 month and less than one year were included in the study. Erectile dysfunction (ED was assessed using International Index of Erectile Function-5 (IIEF-5. Age, education, smoking, monthly income, any drug intake, altitude, duration of stay and weather conditions were correlated independently with ED. Results: Out of 122, 26 (21.3% had no ED, 18 had mild, 28 (14.8% had mild to moderate, 36(29.5% had moderate and 14 (11.5% had severe ED. Advancing age, low monthly income, smoking, high altitude, cold weather and longer duration of stay had significant association with ED (p-value<0.05 while education and use of any drug were not found significantly associated in our study. Conclusion: This study showed a high prevalence of erectile dysfunction among otherwise healthy individuals when exposed to high altitude. Special attention should be paid on individuals with more age, less income and those working or residing at higher altitudes in peak winter season. Smoking and stay for longer durations should also be discouraged.

  12. Physiological aspects of altitude training and the use of altitude simulators

    OpenAIRE

    Ranković Goran; Radovanović Dragan

    2005-01-01

    Altitude training in various forms is widely practiced by athletes and coaches in an attempt to improve sea level endurance. Training at high altitude may improve performance at sea level through altitude acclimatization, which improves oxygen transport and/or utilization, or through hypoxia, which intensifies the training stimulus. This basic physiological aspect allows three training modalities: live high and train high (classic high-altitude training), live low and train high (training thr...

  13. Scientific Approach for Optimising Performance, Health and Safety in High-Altitude Observatories

    Science.gov (United States)

    Böcker, Michael; Vogy, Joachim; Nolle-Gösser, Tanja

    2008-09-01

    The ESO coordinated study “Optimising Performance, Health and Safety in High-Altitude Observatories” is based on a psychological approach using a questionnaire for data collection and assessment of high-altitude effects. During 2007 and 2008, data from 28 staff and visitors involved in APEX and ALMA were collected and analysed and the first results of the study are summarised. While there is a lot of information about biomedical changes at high altitude, relatively few studies have focussed on psychological changes, for example with respect to performance of mental tasks, safety consciousness and emotions. Both, biomedical and psychological changes are relevant factors in occupational safety and health. The results of the questionnaire on safety, health and performance issues demonstrate that the working conditions at high altitude are less detrimental than expected.

  14. Unchanged cerebral blood flow and oxidative metabolism after acclimatization to high altitude

    DEFF Research Database (Denmark)

    Møller, Kirsten; Paulson, Olaf B; Hornbein, Thomas F.

    2002-01-01

    The authors investigated the effect of acclimatization to high altitude on cerebral blood flow and oxidative metabolism at rest and during exercise. Nine healthy, native sea-level residents were studied 3 weeks after arrival at Chacaltaya, Bolivia (5,260 m) and after reacclimatization to sea level....... At high altitude at rest, arterial carbon dioxide tension, oxygen saturation, and oxygen tension were significantly reduced, and arterial oxygen content was increased because of an increase in hemoglobin concentration. Global cerebral blood flow was similar in the four conditions. Cerebral oxygen delivery...... and cerebral metabolic rates of oxygen and glucose also remained unchanged, whereas cerebral metabolic rates of lactate increased slightly but nonsignificantly at high altitude during exercise compared with high altitude at rest. Reaction time was unchanged. The data indicate that cerebral blood flow...

  15. Design study for remotely piloted, high-altitude airplanes powered by microwave energy

    Science.gov (United States)

    Morris, C. E. K., Jr.

    1983-01-01

    A design study has been conducted for unmanned, microwave-powered airplanes that must fly with long endurance at high altitude. They are proposed to conduct communications-relay, observation, or various scientific missions above approximately 55,000 feet altitude. The special characteristics of the microwave-power system and high-altitude, low-speed vehicle are reviewed. Examples of both sizing and performance analysis are used to suggest design procedure guidelines.

  16. Estimating the marine signal in the near infrared for atmospheric correction of satellite ocean-color imagery over turbid waters

    Science.gov (United States)

    Bourdet, Alice; Frouin, Robert J.

    2014-11-01

    The classic atmospheric correction algorithm, routinely applied to second-generation ocean-color sensors such as SeaWiFS, MODIS, and MERIS, consists of (i) estimating the aerosol reflectance in the red and near infrared (NIR) where the ocean is considered black (i.e., totally absorbing), and (ii) extrapolating the estimated aerosol reflectance to shorter wavelengths. The marine reflectance is then retrieved by subtraction. Variants and improvements have been made over the years to deal with non-null reflectance in the red and near infrared, a general situation in estuaries and the coastal zone, but the solutions proposed so far still suffer some limitations, due to uncertainties in marine reflectance modeling in the near infrared or difficulty to extrapolate the aerosol signal to the blue when using observations in the shortwave infrared (SWIR), a spectral range far from the ocean-color wavelengths. To estimate the marine signal (i.e., the product of marine reflectance and atmospheric transmittance) in the near infrared, the proposed approach is to decompose the aerosol reflectance in the near infrared to shortwave infrared into principal components. Since aerosol scattering is smooth spectrally, a few components are generally sufficient to represent the perturbing signal, i.e., the aerosol reflectance in the near infrared can be determined from measurements in the shortwave infrared where the ocean is black. This gives access to the marine signal in the near infrared, which can then be used in the classic atmospheric correction algorithm. The methodology is evaluated theoretically from simulations of the top-of-atmosphere reflectance for a wide range of geophysical conditions and angular geometries and applied to actual MODIS imagery acquired over the Gulf of Mexico. The number of discarded pixels is reduced by over 80% using the PC modeling to determine the marine signal in the near infrared prior to applying the classic atmospheric correction algorithm.

  17. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Haji-Gak mineral district in Afghanistan: Chapter C in Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.; Cagney, Laura E.; Arko, Scott A.; Harbin, Michelle L.

    2012-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Haji-Gak mineral district, which has iron ore deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420-500 nanometer, nm), green (520-600 nm), red (610-690 nm), and near-infrared (760-890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520-770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency ((c)JAXA,2006,2007), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be recreated from this DS. As such, the DS products

  18. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Kharnak-Kanjar mineral district in Afghanistan: Chapter K in Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.; Arko, Scott A.; Harbin, Michelle L.

    2012-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Kharnak-Kanjar mineral district, which has mercury deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420–500 nanometer, nm), green (520–600 nm), red (610–690 nm), and near-infrared (760–890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520–770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency (©JAXA,2007,2008,2010), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be recreated from this DS. As such

  19. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Dusar-Shaida mineral district in Afghanistan: Chapter I in Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.; Arko, Scott A.; Harbin, Michelle L.

    2012-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Dusar-Shaida mineral district, which has copper and tin deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420–500 nanometer, nm), green (520–600 nm), red (610–690 nm), and near-infrared (760–890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520–770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency (©JAXA,2008), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be recreated from this DS. As such, the

  20. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Panjsher Valley mineral district in Afghanistan: Chapter M in Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.; Cagney, Laura E.

    2013-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Panjsher Valley mineral district, which has emerald and silver-iron deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420–500 nanometer, nm), green (520–600 nm), red (610–690 nm), and near-infrared (760–890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520–770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency (©JAXA, 2009, 2010), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be recreated from

  1. High altitude pulmonary edema among "Amarnath Yatris"

    Directory of Open Access Journals (Sweden)

    Parvaiz A Koul

    2013-01-01

    Full Text Available Background: Annual pilgrimage (Yatra to the cave shrine of Shri Amarnath Ji′ is a holy ritual among the Hindu devotees of Lord Shiva. Located in the Himalayan Mountain Range (altitude 13,000 ft in south Kashmir, the shrine is visited by thousands of devotees and altitude sickness is reportedly common. Materials and Methods: More than 600,000 pilgrims visited the cave shrine in 2011 and 2012 with 239 recorded deaths. Thirty one patients with suspected altitude sickness were referred from medical centers en-route the cave to Sher-i-Kashmir Institute of Medical Sciences, a tertiary-care center in capital Srinagar (5,000 ft. The clinical features and the response to treatment were recorded. Results: Thirty-one patients (all lowlanders, 19 male; age 18-60 years, median 41 had presented with acute onset breathlessness of 1-4 days (median 1.9 d starting within 12-24 h of a rapid ascent; accompanied by cough (68%, headache (8%, dizziness and nausea (65%. Sixteen patients had associated encephalopathy. Clinical features on admission included tachypnea ( n = 31, tachycardia ( n = 23, bilateral chest rales ( n = 29, cyanosis ( n = 22 and grade 2-4 encephalopathy. Hypoxemia was demonstrable in 24 cases and bilateral infiltrates on radiologic imaging in 29. Ten patients had evidence of high-altitude cerebral edema. All patients were managed with oxygen, steroids, nifedipine, sildenafil and other supportive measures including invasive ventilation ( n = 3. Three patients died due to multiorgan dysfunction. Conclusions: Altitude sickness is common among Amaranath Yatris from the plains and appropriate educational strategies should be invoked for prevention and prompt treatment.

  2. Novel drugs in the management of acute mountain sickness and high altitude pulmonary edema

    Directory of Open Access Journals (Sweden)

    Sikri G

    2015-12-01

    Full Text Available Gaurav Sikri, Anirban Bhattacharya Department of Physiology, Armed Forces Medical College, Wanowarie, Pune, IndiaWe read with great interest the review article titled “Wilderness medicine at high altitude: recent developments in the field” by Shah et al.1 The authors have comprehensively summarized the recent advances in the field of high altitude medicine relevant to sports and travel medicine. However, Shah et al have described potential drugs for management of high-altitude illnesses, such as acute mountain sickness (AMS, high altitude cerebral edema, and high altitude pulmonary edema (HAPE as one group under the section “Novel drug treatment for AMS”. The pathophysiologies of these two sets of diseases (AMS/high altitude cerebral edema as one and HAPE as another set are different2 and hence it would have been nice to have had the novel drugs described separately to elucidate the therapeutic approach for the two different classes of diseases.View original paper by Shah et al.

  3. Kajian Teknologi High Altitude Platform (HAP [Study of High Altitude Platform (HAP Technology

    Directory of Open Access Journals (Sweden)

    Amry Daulat Gultom

    2016-07-01

    Full Text Available High Altitude Platform (HAP merupakan solusi alternatif untuk mengatasi keterbatasan infrastruktur terestrial maupun satelit. HAP merupakan pesawat ataupun balon udara yang ditempatkan pada ketinggian 20-50 km di atas permukaan bumi. Kelebihan yang utama dari HAP adalah kemudahan dalam penempatan, fleksibilitas, biaya operasionalnya rendah, delay  propagasi rendah, sudut elevasi lebar, cakupan yang luas. Penelitian ini dilakukan untuk mengetahui potensi HAP untuk komunikasi pita lebar dan perkembangannya di Indonesia. Analisis dilakukan secara deskriptif dengan mengolah data literatur yang didapat. Hasil penelitian menunjukkan bahwa di Indonesia terdapat potensi teknologi HAP untuk komunikasi pita lebar dengan lebar pita 2x300 MHz di band 27,9-28,2 GHz dan 31-31,3 GHz. Namun, belum ada peraturan yang mengatur alokasi frekuensi untuk HAP secara khusus di Indonesia.*****High Altitude Platform (HAP has been developed as an alternative solution in order to overcome limitation of terrestrial and satellite communication system. HAP is an aircraft or balloon situated on 20-50 km above the earth. Main advantages of HAP are flexibility in deployment, low propagation delay, wide elevation angle and broad coverage. The research is conducted to gather HAP potential for broadband communication and its development in Indonesia. Analysis is conducted by descriptive analysis from literature study gather. The research result shows that in Indonesia, there is potential of HAP technology for broadband communication with 2x300 MHz bandwidth within 27,9-28,2 GHz and 31-31,3 GHz. Yet, there are no specific regulations managing frequency allocation for HAP in Indonesia.

  4. Difference in blood microcirculation recovery between normal frostbite and high-altitude frostbite

    Directory of Open Access Journals (Sweden)

    Ming-ke JIAO

    2017-02-01

    Full Text Available Objective To determine the difference in blood microcirculation recovery between normal frostbite and high-altitude frostbite during the wound healing. Methods Twenty four male rats were randomly divided into control group (n=8, normal frostbite group (n=8, and high-altitude group (n=8. The normal frostbite group rats were frozen to produce mid-degree frostbite models by controlling the freezing time with liquid nitrogen penetration equipment. The high-altitude frostbite group rats were acclimated to a hypoxic and low-pressure environment for 1 week, and then the high-altitude frostbite models were constructed by the same way with liquid nitrogen penetration apparatus. On days 3, 7, 11, 15, 19, and 23 after modeling, the recovery situation of blood circulation of each group was observed with contrast ultrasonography by injecting SonoVue micro-bubble into rats' tail. Finally, the micro-bubble concentration (MC was calculated to confirm the blood circulation recovery with software Image Pro. Results At different time points, the wound area of the high-altitude frostbite group was bigger than that of the normal frostbite group, and the MC of control group was always about (27±0.2×109/ml. On day 3, 7, 11, 15, 19, and 23, the MC was significantly lower in the high-altitude frostbite group than in the control group and normal frostbite group (P<0.05. The MC of normal frostbite group was significantly lower than that of the control group on day 3, 7, 11, 15 and 19 (P<0.05. In addition, no obvious difference in MC was found between normal group and control group on the 23th day (P<0.05. Conclusion The blood microcirculation recovery after high-altitude frostbite is significantly slower than the normal frostbite. DOI: 10.11855/j.issn.0577-7402.2017.01.13

  5. Civilian Training in High-Altitude Flight Physiology

    Science.gov (United States)

    1991-08-01

    A survey was conducted to determine if training in high-altitude physiology should : be required for civilian pilots; what the current status of such training was; and, : if required, what should be included in an ideal curriculum. The survey include...

  6. A DECADE OF MAPPING SUBMERGED AQUATIC VEGETATION USING COLOR INFRARED AERIAL PHOTOGRAPHY: METHODS USED AND LESSONS LEARNED

    Science.gov (United States)

    Annual color infrared aerial photographs acquired annually between 1997 and 2007 were used to classify distributions of intertidal and shallow subtidal native eelgrass Zostera marina and non-indigenous dwarf eelgrass Z. japonica in lower Yaquina estuary, Oregon. The use of digit...

  7. Aspirated Compressors for High Altitude Engines, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Aurora Flight Sciences proposes to incorporate aspirated compressor technology into a high altitude, long endurance (HALE) concept engine. Aspiration has been proven...

  8. Study on Oxygen Supply Standard for Physical Health of Construction Personnel of High-Altitude Tunnels

    Directory of Open Access Journals (Sweden)

    Chun Guo

    2015-12-01

    Full Text Available The low atmospheric pressure and low oxygen content in high-altitude environment have great impacts on the functions of human body. Especially for the personnel engaged in complicated physical labor such as tunnel construction, high altitude can cause a series of adverse physiological reactions, which may result in multiple high-altitude diseases and even death in severe cases. Artificial oxygen supply is required to ensure health and safety of construction personnel in hypoxic environments. However, there are no provisions for oxygen supply standard for tunnel construction personnel in high-altitude areas in current tunnel construction specifications. As a result, this paper has theoretically studied the impacts of high-altitude environment on human bodies, analyzed the relationship between labor intensity and oxygen consumption in high-altitude areas and determined the critical oxygen-supply altitude values for tunnel construction based on two different standard evaluation systems, i.e., variation of air density and equivalent PIO2. In addition, it has finally determined the oxygen supply standard for construction personnel in high-altitude areas based on the relationship between construction labor intensity and oxygen consumption.

  9. Three approaches to the classification of inland wetlands. [Dismal Swamp, Tennessee, and Florida

    Science.gov (United States)

    Gammon, P. T.; Malone, D.; Brooks, P. D.; Carter, V.

    1977-01-01

    In the Dismal Swamp project, seasonal, color-infrared aerial photographs and LANDSAT digital data were interpreted for a detailed analysis of the vegetative communities in a large, highly altered wetland. In Western Tennessee, seasonal high altitude color-infrared aerial photographs provided the hydrologic and vegetative information needed to map inland wetlands, using a classification system developed for the Tennessee Valley Region. In Florida, color-infrared aerial photographs were analyzed to produce wetland maps using three existing classification systems to evaluate the information content and mappability of each system. The methods used in each of the three projects can be extended or modified for use in the mapping of inland wetlands in other parts of the United States.

  10. Climate Change Impacts on High-Altitude Ecosystems

    OpenAIRE

    Harald Pauli

    2016-01-01

    Reviewed: Climate Change Impacts on High-Altitude Ecosystems By Münir Öztürk, Khalid Rehman Hakeem, I. Faridah-Hanum and Efe. Recep, Cham, Switzerland: Springer International Publishing, 2015. xvii + 696 pp. US$ 239.00. ISBN 978-3-319-12858-0.

  11. Effect of egg composition and oxidoreductase on adaptation of Tibetan chicken to high altitude.

    Science.gov (United States)

    Jia, C L; He, L J; Li, P C; Liu, H Y; Wei, Z H

    2016-07-01

    Tibetan chickens have good adaptation to hypoxic conditions, which can be reflected by higher hatchability than lowland breeds when incubated at high altitude. The objective of this trial was to study changes in egg composition and metabolism with regards the adaptation of Tibetan chickens to high altitude. We measured the dry weight of chicken embryos, egg yolk, and egg albumen, and the activity of lactate dehydrogenase (LDH) and succinic dehydrogenase (SDH) in breast muscle, heart, and liver from embryos of Tibetan chicken and Dwarf chicken (lowland breed) incubated at high (2,900 m) and low (100 m) altitude. We found that growth of chicken embryos was restricted at high altitude, especially for Dwarf chicken embryos. In Tibetan chicken, the egg weight was lighter, but the dry weight of egg yolk was heavier than that of Dwarf chicken. The LDH activities of the three tissues from the high altitude groups were respectively higher than those of the lowland groups from d 15 to hatching, except for breast muscle of Tibetan chicken embryos on d 15. In addition, under the high altitude environment, the heart tissue from Tibetan chicken had lower LDH activity than that from Dwarf chicken at d 15 and 18. The lactic acid content of blood from Tibetan chicken embryos was lower than that of Dwarf chicken at d 12 and 15 of incubation at high altitude. There was no difference in SDH activity in the three tissues between the high altitude groups and the lowland groups except in three tissues of hatchlings and at d 15 of incubation in breast muscle, nor between the two breeds at high altitude except in the heart of hatchlings. Consequently, the adaptation of Tibetan chicken to high altitude may be associated with higher quantities of yolk in the egg and a low metabolic oxygen demand in tissue, which illuminate the reasons that the Tibetan chicken have higher hatchability with lower oxygen transport ability. © 2016 Poultry Science Association Inc.

  12. Color design model of high color rendering index white-light LED module.

    Science.gov (United States)

    Ying, Shang-Ping; Fu, Han-Kuei; Hsieh, Hsin-Hsin; Hsieh, Kun-Yang

    2017-05-10

    The traditional white-light light-emitting diode (LED) is packaged with a single chip and a single phosphor but has a poor color rendering index (CRI). The next-generation package comprises two chips and a single phosphor, has a high CRI, and retains high luminous efficacy. This study employs two chips and two phosphors to improve the diode's color tunability with various proportions of two phosphors and various densities of phosphor in the silicone used. A color design model is established for color fine-tuning of the white-light LED module. The maximum difference between the measured and color-design-model simulated CIE 1931 color coordinates is approximately 0.0063 around a correlated color temperature (CCT) of 2500 K. This study provides a rapid method to obtain the color fine-tuning of a white-light LED module with a high CRI and luminous efficacy.

  13. Incidence and Symptoms of High Altitude Illness in South Pole Workers: Antarctic Study of Altitude Physiology (ASAP

    Directory of Open Access Journals (Sweden)

    Paul J. Anderson

    2011-01-01

    Full Text Available Introduction Each year, the US Antarctic Program rapidly transports scientists and support personnel from sea level (SL to the South Pole (SP, 2835 m providing a unique natural laboratory to quantify the incidence of acute mountain sickness (AMS, patterns of altitude related symptoms and the field effectiveness of acetazolamide in a highly controlled setting. We hypothesized that the combination of rapid ascent (3 hr, accentuated hypobarism (relative to altitude, cold, and immediate exertion would increase altitude illness risk. Methods Medically screened adults (N = 246, age = 37 ± 11 yr, 30% female, BMI = 26 ± 4 kg/m 2 were recruited. All underwent SL and SP physiological evaluation, completed Lake Louise symptom questionnaires (LLSQ, to define AMS, and answered additional symptom related questions (eg, exertional dyspnea, mental status, cough, edema and general health, during the 1st week at altitude. Acetazolamide, while not mandatory, was used by 40% of participants. Results At SP, the barometric pressure resulted in physiological altitudes that approached 3400 m, while T ° C averaged -42, humidity 0.03%. Arterial oxygen saturation averaged 89% ± 3%. Overall, 52% developed LLSQ defined AMS. The most common symptoms reported were exertional dyspnea-(87%, sleeping difficulty-(74%, headache-(66%, fatigue-(65%, and dizziness/lightheadedness-(46%. Symptom severity peaked on days 1-2, yet in >20% exertional dyspnea, fatigue and sleep problems persisted through day 7. AMS incidence was similar between those using acetazolamide and those abstaining (51 vs. 52%, P = 0.87. Those who used acetazolamide tended to be older, have less altitude experience, worse symptoms on previous exposures, and less SP experience. Conclusion The incidence of AMS at SP tended to be higher than previously reports in other geographic locations at similar altitudes. Thus, the SP constitutes a more intense altitude exposure than might be expected considering physical

  14. Butterflies of the high altitude Atacama Desert: habitat use and conservation

    Directory of Open Access Journals (Sweden)

    Emma eDespland

    2014-09-01

    Full Text Available The butterfly fauna of the high-altitude desert of Northern Chile, though depauperate, shows high endemism, is poorly known and is of considerable conservation concern. This study surveys butterflies along the Andean slope between 2400 and 500 m asl (prepuna, puna and Andean steppe habitats as well as in high and low altitude wetlands and in the neoriparian vegetation of agricultural sites. We also include historical sightings from museum records. We compare abundances between altitudes, between natural and impacted sites, as well as between two sampling years with different precipitation regimes. The results confirm high altitudinal turnover and show greatest similarity between wetland and slope faunas at similar altitudes. Results also underscore vulnerability to weather fluctuations, particularly in the more arid low-altitude sites, where abundances were much lower in the low precipitation sampling season and several species were not observed at all. Finally, we show that some species have shifted to the neoriparian vegetation of the agricultural landscape, whereas others were only observed in less impacted habitats dominated by native plants. These results suggest that acclimation to novel habitats depends on larval host plant use. The traditional agricultural environment can provide habitat for many, but not all, native butterfly species, but an estimation of the value of these habitats requires better understanding of butterfly life-history strategies and relationships with host plants.

  15. High altitude-induced albuminuria in normal man is enhanced by infusion of low-dose dopamine

    DEFF Research Database (Denmark)

    Hansen, J M; Kanstrup, I L; Richalet, J P

    1996-01-01

    -85) (median with quartiles in parentheses) at high altitude. High altitude hypoxia increased Ualb from 3.2 micrograms min-1 (2.7-3.5) to 5.0 micrograms min-1 (3.3-6.6) (p ... flow (ERPF) from 465 ml min-1 (412-503) to 410 ml min-1 (385-451) (p high altitude. Dopamine...... increased ERPF, GFR, CLi, CNa, and decreased the filtration fraction in both environments. Infusion of dopamine further increased Ualb to 10.5 micrograms min-1 (5.5-64.8) (p high altitude, but had no effect on Ualb at sea level. In conclusion, high altitude hypoxia per se increases the urinary...

  16. Aerial Photography and Imagery, Ortho-Corrected, 4 inch aerial photography (color, infrared, and color oblique) in urban areas, 1 foot in national forest, Published in 2006, 1:600 (1in=50ft) scale, Los Angeles County Government.

    Data.gov (United States)

    NSGIC Local Govt | GIS Inventory — Aerial Photography and Imagery, Ortho-Corrected dataset current as of 2006. 4 inch aerial photography (color, infrared, and color oblique) in urban areas, 1 foot in...

  17. Climate Change Impacts on High-Altitude Ecosystems

    Directory of Open Access Journals (Sweden)

    Harald Pauli

    2016-02-01

    Full Text Available Reviewed: Climate Change Impacts on High-Altitude Ecosystems By Münir Öztürk, Khalid Rehman Hakeem, I. Faridah-Hanum and Efe. Recep, Cham, Switzerland: Springer International Publishing, 2015. xvii + 696 pp. US$ 239.00. ISBN 978-3-319-12858-0.

  18. Spitzer sage survey of the large magellanic cloud. II. Evolved stars and infrared color-magnitude diagrams

    NARCIS (Netherlands)

    Blum, R. D.; Mould, J. R.; Olsen, K. A.; Frogel, J. A.; Meixner, M.; Markwick-Kemper, F.; Indebetouw, R.; Whitney, B.; Meade, M.; Babler, B.; Churchwell, E. B.; Gordon, K.; Engelbracht, C.; For, B. -Q.; Misselt, K.; Vijh, U.; Leitherer, C.; Volk, K.; Points, S.; Reach, W.; Hora, J. L.; Bernard, J. -P.; Boulanger, F.; Bracker, S.; Cohen, M.; Fukui, Y.; Gallagher, J.; Gorjian, V.; Harris, J.; Kelly, D.; Kawamura, A.; Latter, W. B.; Madden, S.; Mizuno, A.; Mizuno, N.; Oey, M. S.; Onishi, T.; Paladini, R.; Panagia, N.; Perez-Gonzalez, P.; Shibai, H.; Sato, S.; Smith, L.; Staveley-Smith, L.; Tielens, A.G.G.M; Ueta, T.; Van Dyk, S.; Zaritsky, D.; Werner, M.J.

    Color-magnitude diagrams (CMDs) are presented for the Spitzer SAGE (Surveying the Agents of a Galaxy's Evolution) survey of the Large Magellanic Cloud (LMC). IRAC and MIPS 24 mu m epoch 1 data are presented. These data represent the deepest, widest mid-infrared CMDs of their kind ever produced in

  19. SPLENIC INFARCTION: an intriguing and important cause of pain abdomen in high altitude

    Directory of Open Access Journals (Sweden)

    P. K. Hota

    2015-01-01

    Full Text Available Background: Patients with Sickle cell trait (SCT are usually asymptomatic. They are usually unaware of their condition unless they have a family history. There are specific situations, where these people suffer from the effects of sickle cell trait. Splenic syndrome at high altitude is one of the specific problems. It is usually seen after a patient with SCT has been inducted to high altitude like in case of mountaineers and military personnel deployed in high altitude warfare. Pain abdomen due to splenic infarction in individuals with SCT is one of the manifestations. These patients, if diagnosed in time, they can be spared from unnecessary surgical interventions. We present herewith our experience of splenic infarction due to SCT in high altitude and their management.

  20. Comparison of Color Fundus Photography, Infrared Fundus Photography, and Optical Coherence Tomography in Detecting Retinal Hamartoma in Patients with Tuberous Sclerosis Complex.

    Science.gov (United States)

    Bai, Da-Yong; Wang, Xu; Zhao, Jun-Yang; Li, Li; Gao, Jun; Wang, Ning-Li

    2016-05-20

    A sensitive method is required to detect retinal hamartomas in patients with tuberous sclerosis complex (TSC). The aim of the present study was to compare the color fundus photography, infrared imaging (IFG), and optical coherence tomography (OCT) in the detection rate of retinal hamartoma in patients with TSC. This study included 11 patients (22 eyes) with TSC, who underwent color fundus photography, IFG, and spectral-domain OCT to detect retinal hamartomas. TSC1 and TSC2RESULTS: The mean age of the 11 patients was 8.0 ± 2.1 years. The mean spherical equivalent was -0.55 ± 1.42 D by autorefraction with cycloplegia. In 11 patients (22 eyes), OCT, infrared fundus photography, and color fundus photography revealed 26, 18, and 9 hamartomas, respectively. The predominant hamartoma was type I (55.6%). All the hamartomas that detected by color fundus photography or IFG can be detected by OCT. Among the methods of color fundus photography, IFG, and OCT, the OCT has higher detection rate for retinal hamartoma in TSC patients; therefore, OCT might be promising for the clinical diagnosis of TSC.

  1. Experimental StudyHigh Altitude Forced Convective Cooling of Electromechanical Actuation Systems

    Science.gov (United States)

    2016-01-01

    34 Massachusetts Institute of Technology , 1989. [3] FedBizOps.Gov, " Integrated Vehicle Energy Technology (INVENT) Development Program for the 6th...AFRL-RQ-WP-TR-2016-0043 EXPERIMENTAL STUDY—HIGH ALTITUDE FORCED CONVECTIVE COOLING OF ELECTROMECHANICAL ACTUATION SYSTEMS Evan M. Racine...TITLE AND SUBTITLE EXPERIMENTAL STUDY—HIGH ALTITUDE FORCED CONVECTIVE COOLING OF ELECTROMECHANICAL ACTUATION SYSTEMS 5a. CONTRACT NUMBER In-house

  2. Text mining and network analysis to find functional associations of genes in high altitude diseases.

    Science.gov (United States)

    Bhasuran, Balu; Subramanian, Devika; Natarajan, Jeyakumar

    2018-05-02

    Travel to elevations above 2500 m is associated with the risk of developing one or more forms of acute altitude illness such as acute mountain sickness (AMS), high altitude cerebral edema (HACE) or high altitude pulmonary edema (HAPE). Our work aims to identify the functional association of genes involved in high altitude diseases. In this work we identified the gene networks responsible for high altitude diseases by using the principle of gene co-occurrence statistics from literature and network analysis. First, we mined the literature data from PubMed on high-altitude diseases, and extracted the co-occurring gene pairs. Next, based on their co-occurrence frequency, gene pairs were ranked. Finally, a gene association network was created using statistical measures to explore potential relationships. Network analysis results revealed that EPO, ACE, IL6 and TNF are the top five genes that were found to co-occur with 20 or more genes, while the association between EPAS1 and EGLN1 genes is strongly substantiated. The network constructed from this study proposes a large number of genes that work in-toto in high altitude conditions. Overall, the result provides a good reference for further study of the genetic relationships in high altitude diseases. Copyright © 2018 Elsevier Ltd. All rights reserved.

  3. Cognitive Changes during Prolonged Stay at High Altitude and Its Correlation with C-Reactive Protein.

    Directory of Open Access Journals (Sweden)

    Sheng Li Hu

    Full Text Available Hypersensitive C-reaction protein (hsCRP may be a risk factor for cognitive impairment resulting from Alzheimer's disease (AD, stroke, and vascular dementia. This study explored the correlation of peripheral blood hsCRP level with cognitive decline due to high altitude exposure. The study was conducted on 100 male military participants who had never been to high altitude. Cerebral oxygen saturation monitoring, event related potentials (P300, N200 detection, and neurocognitive assessment was performed and total hsCRP, interleukin-6 (IL-6, and homocysteine was estimated at 500 m altitude, 3650 m altitude, 3 day, 1, and 3 month post arriving at the base camp (4400 m, and 1 month after coming back to the 500 m altitude. High altitude increased brain oxygen saturation, prolonged P300 and N200 latencies, injured cognitive functions, and raised plasma hsCRP levels. But they all recovered in varying degrees at 1 and 3 month post arriving at the base camp (4400 m. P300 latencies and hsCRP levels were strongly correlated to cognitive performances. These results suggested that cognitive deterioration occurred during the acute period of exposure to high altitude and may recover probably owning to acclimatization after extended stay at high altitude. Plasma hsCRP is inversely correlated to neurological cognition and it may be a potential biomarker for the prediction of high altitude induced cognitive dysfunction.

  4. Functions and Design Scheme of Tibet High Altitude Test Base

    Institute of Scientific and Technical Information of China (English)

    Yu Yongqing; Guo Jian; Yin Yu; Mao Yan; Li Guangfan; Fan Jianbin; Lu Jiayu; Su Zhiyi; Li Peng; Li Qingfeng; Liao Weiming; Zhou Jun

    2010-01-01

    @@ The functional orientation of the Tibet High Altitude Test Base, subordinated to the State Grid Corporation of China (SGCC), is to serve power transmission projects in high altitude areas, especially to provide technical support for southwestern hydropower delivery projects by UHVDC transmission and Qinghai-Tibet grid interconnection project. This paper presents the matters concerned during siting and planning, functions,design scheme, the main performances and parameters of the test facilities, as well as the tests and research tasks already carried out.

  5. MULTI-COLOR OPTICAL AND NEAR-INFRARED LIGHT CURVES OF 64 STRIPPED-ENVELOPE CORE-COLLAPSE SUPERNOVAE

    Energy Technology Data Exchange (ETDEWEB)

    Bianco, F. B.; Modjaz, M. [Center for Cosmology and Particle Physics, New York University, 4 Washington Place, New York, NY 10003 (United States); Hicken, M.; Friedman, A.; Kirshner, R. P.; Challis, P.; Marion, G. H. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Bloom, J. S. [Department of Astronomy, University of California, Berkeley, CA 94720-3411 (United States); Wood-Vasey, W. M. [PITT PACC, Department of Physics and Astronomy, 3941 O' Hara Street, University of Pittsburgh, Pittsburgh, PA 15260 (United States); Rest, A., E-mail: fb55@nyu.edu [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States)

    2014-08-01

    We present a densely sampled, homogeneous set of light curves of 64 low-redshift (z ≲ 0.05) stripped-envelope supernovae (SNe of Type IIb, Ib, Ic, and Ic-BL). These data were obtained between 2001 and 2009 at the Fred L. Whipple Observatory (FLWO) on Mount Hopkins in Arizona, with the optical FLWO 1.2 m and the near-infrared (NIR) Peters Automated Infrared 1.3 m telescopes. Our data set consists of 4543 optical photometric measurements on 61 SNe, including a combination of U BV RI, U BV r{sup ′}i{sup ′}, and u{sup ′} BV r{sup ′}i{sup ′}, and 1919 JHK{sub s} NIR measurements on 25 SNe. This sample constitutes the most extensive multi-color data set of stripped-envelope SNe to date. Our photometry is based on template-subtracted images to eliminate any potential host-galaxy light contamination. This work presents these photometric data, compares them with data in the literature, and estimates basic statistical quantities: date of maximum, color, and photometric properties. We identify promising color trends that may permit the identification of stripped-envelope SN subtypes from their photometry alone. Many of these SNe were observed spectroscopically by the Harvard-Smithsonian Center for Astrophysics (CfA) SN group, and the spectra are presented in a companion paper. A thorough exploration that combines the CfA photometry and spectroscopy of stripped-envelope core-collapse SNe will be presented in a follow-up paper.

  6. The use of Kodak aerochrome infrared color film, type 2443, as a remote sensing tool

    Science.gov (United States)

    Cooper, G. R.; Bowen, R. L.; Gausman, H. W.

    1972-01-01

    An infrared color film, Kodak Aerochrome, type 2443, has replaced the 8443 film. The 2443 has lower contrast than the 8443 film, and allows deeper probing into areas that appear as solid black shadows on the 8443 film. The cyan layer of 2443 is approximately 1 1/2 stops slower, at a density of 1.4, than the yellow and magenta emulsion layers.

  7. Effect of phosphate supplementation on oxygen delivery at high altitude

    Science.gov (United States)

    Jain, S. C.; Singh, M. V.; Rawal, S. B.; Sharma, V. M.; Divekar, H. M.; Tyagi, A. K.; Panwar, M. R.; Swamy, Y. V.

    1987-09-01

    In the present communication, effect of low doses of phosphate supplementation on short-term high altitude adaptation has been examined. Studies were carried out in 36 healthy, male, sea-level residents divided in a double blind fashion into drug and placebo treated groups. 3.2 mmol of phosphate were given orally to each subject of the drug treated group once a day for 4 days on arrival at an altitude of 3,500 m. Sequential studies were done in the subjects in both groups on the 3rd, 7th, 14th and 21st day of their altitude stay. Haemoglobin, haematocrit, erythrocyte and reticulocyte counts increased to the similar extent in both groups. Blood pH, pO2 and adenosine tri-phosphate (ATP) did not differ between the two groups. On 3rd day of the altitude stay, inorganic phosphate and 2,3-diphosphoglycerate (2,3 DPG) levels in the drug treated group increased significantly as compared to the placebo group. No significant difference in inorganic phosphate and 2,3 DPG was observed later on in the two groups. Psychological and clinical tests also indicated that the drug treated subjects felt better as compared to the placebo treated subjects. The present study suggests that low doses of phosphate increases circulating 2,3-DPG concentration which in turn brings about beneficial effect towards short term high altitude adaptation.

  8. Differentiation of pulmonary embolism from high altitude pulmonary edema

    International Nuclear Information System (INIS)

    Khan, D.A.; Hashim, R.; Mirza, T.M.; Matloob-ur-Rehman, M.

    2003-01-01

    Objective: To differentiate the high altitude pulmonary edema (HAPE) from pulmonary embolism (PE) by clinical probability model of PE, lactate dehydrogenase (LDH), aspartate transaminase (AST) and D-dimer assays at high altitude. Subjects and Methods: Consecutive 40 patients evacuated from height > 3000 meters with symptoms of PE or HAPE were included. Clinical pretest probabilities scores of PE, Minutex D-dimer assay (Biopool international) and cardiac enzymes estimation by IFCC approved methods, were used for diagnosis. Mann-Whitney U test was applied by using SPSS and level of significance was taken at (p 500 ng/ml. Plasma D-dimer of 500 ng/ml was considered as cut-off value; 6(66.7%) patients of PE could be diagnosed and 30 (96.7%) cases of HAPE excluded indicating very good negative predictive value. Serum LDH, AST and CK were raised above the reference ranges in 8 (89%), 7 (78%) and 3 (33%) patients of PE as compared to 11 (35%), 6 (19%) and 9 (29%) of HAPE respectively. Conclusion: Clinical assessment in combination with D-dimer assay, LDH and AST can be used for timely differentiation of PE from HAPE at high altitude where diagnostic imaging procedures are not available. (author)

  9. High-resolution far-infrared observations of the galactic center

    International Nuclear Information System (INIS)

    Harvey, P.M.; Campbell, M.F.; Hoffmann, W.F.

    1976-01-01

    A map at 53 μ with 17'' resolution and three-color observations at 53 μ, 100 μ, and 175 μ with approx.30'' beams of Sgr A are presented. Sagittarius A is resolved into two main sources, one associated with the cluster of strong 10 μ sources and another approx.45'' to the southwest coincident with a weak 10 μ source. The dust temperature peaks near the strong 10 μ sources, but the 100 μ and 175 μ fluxes and the far-infrared optical depth are greatest near the southwest source. The amount of dust required to explain the far-infrared emission is comparable to that observed in absorption in the near-infrared

  10. Silicon isotope separation utilizing infrared multiphoton dissociation of Si{sub 2}F{sub 6} irradiated with two-color CO{sub 2} laser light

    Energy Technology Data Exchange (ETDEWEB)

    Yokoyama, Atsushi; Ohba, Hironori; Hashimoto, Masashi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Ishii, Takeshi; Ohya, Akio [Nuclear Development Corp., Tokai, Ibaraki (Japan); Arai, Shigeyoshi [Hill Research Co. Ltd., Tokyo (Japan)

    2002-08-01

    Silicon isotope separation has been done by utilizing the Infrared Multiphoton Dissociation (IRMPD) of Si{sub 2}F{sub 6} irradiated with two-color CO{sub 2} laser lights. The two-color excitation method improved the separation efficiency keeping the high enrichment factors. For example, 99.74% of {sup 28}Si was obtained at 49.63% dissociation of Si{sub 2}F{sub 6} after the simultaneous irradiation of 200 pulses with 966.23 cm{sup -1} photons (0.084 J/cm{sup 2}) and 954.55 cm{sup -1} photons (0.658 J/cm{sup 2}), while 2000 pulses were needed to obtain 99.35% of {sup 28}Si at 35.6% dissociation in the case of only one-color irradiation at 954.55 cm{sup -1} (0.97 J/cm{sup 2}). (author)

  11. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Ghunday-Achin mineral district in Afghanistan, in Davis, P.A, compiler, Local-area-enhanced, high-resolution natural-color and color-infrared satellite-image mosaics of mineral districts in Afghanistan

    Science.gov (United States)

    Davis, Philip A.; Arko, Scott A.; Harbin, Michelle L.; Davis, Philip A.

    2013-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Ghunday-Achin mineral district, which has magnesite and talc deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420–500 nanometer, nm), green (520–600 nm), red (610–690 nm), and near-infrared (760–890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520–770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency (©JAXA,2008,2009), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be recreated from this DS. As

  12. Measurements of radioactive dust in high altitude air

    International Nuclear Information System (INIS)

    Kobayashi, Mika; Kohara, Eri; Muronoi, Naohiro; Masuda, Yousuke; Midou, Tomotaka; Ishida, Yukiko; Shimizu, Toshihiko; Saga, Minoru; Endo, Hiromu

    2012-01-01

    The radioactivity in samples of airborne dust was measured. The samples had been collected at high altitude by the Japan Air Self-Defense Force. The data were obtained for the gross beta activity, gamma nuclide determination and radiochemical analysis. It was shown that there was no appreciable difference between the activity levels obtained in this time and in the year before. Seasonal variations were not very pronounced. It was found that the radioactivity at high altitude had been stable at a low level. Radioactive gases (gaseous radioiodine and xenon gas) were not detected. This report does not include the result on radionuclide measurements that Technical Research and Development Institute executed for examining the nuclear emergency situation at Fukushima Daiichi and Daini nuclear power plants after Tohoku Region Pacific Ocean Earthquake on March 11, 2011. (author)

  13. Rare Particle Searches with the high altitude SLIM experiment

    CERN Document Server

    Balestra, S; Fabbri, F; Giacomelli, G; Giacomelli, R; Giorgini, M; Kumar, A; Manzoor, S; McDonald, J; Margiotta, A; Medinaceli, E; Nogales, J; Patrizii, L; Popa, V; Quereshi, I; Saavedra, O; Sher, G; Shahzad, M; Spurio, M; Ticona, R; Togo, V; Velarde, A; Zanini, A

    2005-01-01

    The search for rare particles in the cosmic radiation remains one of the main aims of non-accelerator particle astrophysics. Experiments at high altitude allow lower mass thresholds with respect to detectors at sea level or underground. The SLIM experiment is a large array of nuclear track detectors located at the Chacaltaya High Altitude Laboratory (5290 m a.s.l.). The preliminary results from the analysis of a part of the first 236 sq.m exposed for more than 3.6 y are here reported. The detector is sensitive to Intermediate Mass Magnetic Monopoles and to SQM nuggets and Q-balls, which are possible Dark Matter candidates.

  14. High Altitude Balloons as a Platform for Space Radiation Belt Science

    Science.gov (United States)

    Mazzino, L.; Buttenschoen, A.; Farr, Q.; Hodgson, C.; Johnson, W.; Mann, I. R.; Rae, J.; University of Alberta High Altitude Balloons (UA-HAB)

    2011-12-01

    The goals of the University of Alberta High Altitude Balloons Program (UA-HAB) are to i) use low cost balloons to address space radiation science, and ii) to utilise the excitement of "space mission" involvement to promote and facilitate the recruitment of undergraduate and graduate students in physics, engineering, and atmospheric sciences to pursue careers in space science and engineering. The University of Alberta High Altitude Balloons (UA-HAB) is a unique opportunity for University of Alberta students (undergraduate and graduate) to engage in the hands-on design, development, build, test and flight of a payload to operate on a high altitude balloon at around 30km altitude. The program development, including formal design and acceptance tests, reports and reviews, mirror those required in the development of an orbital satellite mission. This enables the students to gain a unique insight into how space missions are flown. UA-HAB is a one and half year program that offers a gateway into a high-altitude balloon mission through hands on experience, and builds skills for students who may be attracted to participate in future space missions in their careers. This early education will provide students with the experience necessary to better assess opportunities for pursuing a career in space science. Balloons offer a low-cost alternative to other suborbital platforms which can be used to address radiation belt science goals. In particular, the participants of this program have written grant proposal to secure funds for this project, have launched several 'weather balloon missions', and have designed, built, tested, and launched their particle detector called "Maple Leaf Particle Detector". This detector was focussed on monitoring cosmic rays and space radiation using shielded Geiger tubes, and was flown as one of the payloads from the institutions participating in the High Altitude Student Platform (HASP), organized by the Louisiana State University and the Louisiana

  15. Sequencing of 50 human exomes reveals adaptation to high altitude

    DEFF Research Database (Denmark)

    Yi, Xin; Liang, Yu; Huerta-Sanchez, Emilia

    2010-01-01

    Residents of the Tibetan Plateau show heritable adaptations to extreme altitude. We sequenced 50 exomes of ethnic Tibetans, encompassing coding sequences of 92% of human genes, with an average coverage of 18x per individual. Genes showing population-specific allele frequency changes, which repres...... in genetic adaptation to high altitude.......Residents of the Tibetan Plateau show heritable adaptations to extreme altitude. We sequenced 50 exomes of ethnic Tibetans, encompassing coding sequences of 92% of human genes, with an average coverage of 18x per individual. Genes showing population-specific allele frequency changes, which...... represent strong candidates for altitude adaptation, were identified. The strongest signal of natural selection came from endothelial Per-Arnt-Sim (PAS) domain protein 1 (EPAS1), a transcription factor involved in response to hypoxia. One single-nucleotide polymorphism (SNP) at EPAS1 shows a 78% frequency...

  16. Relative Match Intensities at High Altitude in Highly-Trained Young Soccer Players (ISA3600).

    Science.gov (United States)

    Buchheit, Martin; Hammond, Kristal; Bourdon, Pitre C; Simpson, Ben M; Garvican-Lewis, Laura A; Schmidt, Walter F; Gore, Christopher J; Aughey, Robert J

    2015-03-01

    To compare relative match intensities of sea-level versus high-altitude native soccer players during a 2-week camp at 3600 m, data from 7 sea-level (Australian U17 National team, AUS) and 6 high-altitude (a Bolivian U18 team, BOL) native soccer players were analysed. Two matches were played at sea-level and three at 3600 m on Days 1, 6 and 13. The Yo-Yo Intermittent recovery test (vYo-YoIR1) was performed at sea-level, and on Days 3 and 10. Match activity profiles were measured via 10-Hz GPS. Distance covered >14.4 km.h(-1) (D>14.4 km·h(-1)) and >80% of vYo-YoIR1 (D>80%vYo-YoIR1) were examined. Upon arrival at altitude, there was a greater decrement in vYo-YoIR1 (Cohen's d +1.0, 90%CL ± 0.8) and D>14.4 km·h(-1) (+0.5 ± 0.8) in AUS. D>14.4 km.h(-1) was similarly reduced relative to vYo-YoIR1 in both groups, so that D>80%vYo-YoIR1 remained similarly unchanged (-0.1 ± 0.8). Throughout the altitude sojourn, vYo-YoIR1 and D>14.4 km·h(-1) increased in parallel in AUS, so that D>80%vYo-YoIR1 remained stable in AUS (+6.0%/match, 90%CL ± 6.7); conversely D>80%vYo-YoIR1 decreased largely in BOL (-12.2%/match ± 6.2). In sea-level natives competing at high-altitude, changes in match running performance likely follow those in high-intensity running performance. Bolivian data confirm that increases in 'fitness' do not necessarily translate into greater match running performance, but rather in reduced relative exercise intensity. Key pointsWhen playing at high-altitude, players may alter their activities during matches in relation to their transient maximal physical capacities, possibly to maintain a 'tolerable' relative exercise intensity.While there is no doubt that running performance per se in not the main determinant of match outcomes (Carling, 2013), fitness levels influence relative match intensity (Buchheit et al., 2012, Mendez-Villanueva et al., 2013), which in-turn may impact on decision making and skill performance (Rampinini et al., 2008).In the context of

  17. Nutrição para os praticantes de exercício em grandes altitudes Nutritional strategy for exercising in high altitudes

    Directory of Open Access Journals (Sweden)

    Caroline Buss

    2006-02-01

    Full Text Available Quando o atleta ascende a uma grande altitude, ele é exposto a uma pressão barométrica reduzida, e os efeitos fisiológicos que acompanham estas mudanças da pressão atmosférica podem ter grande influência sobre o seu organismo e seu desempenho físico. Acredita-se que a hipóxia seja responsável pelo início de uma cascata de eventos sinalizadores que, ao final, levam à adaptação à altitude. A exposição aguda à hipóxia provoca sonolência, fadiga mental e muscular e prostração. Cefaléia, náusea e anorexia são sintomas provocados pela Doença Aguda das Montanhas, que pode ocorrer nos primeiros dias de permanência na altitude. Uma estratégia nutricional adequada é fundamental para que o organismo não sofra nenhum estresse adicional. O objetivo deste trabalho foi apresentar os principais efeitos da altitude sobre o organismo e sobre o desempenho físico, discutir e/ou sugerir recomendações nutricionais para esta situação e, se possível, apresentar uma orientação nutricional prática para o atleta na altitude. Algumas das principais conclusões encontradas foram: o consumo energético deve ser aumentado; é fundamental monitorar a quantidade de líquidos ingeridos e escolher alimentos agradáveis ao paladar, ricos em energia e nutrientes. Recomenda-se trabalhar com um nutricionista do esporte com antecedência, para que um plano alimentar individual seja elaborado e colocado em prática antes mesmo da viagem à altitude.When athletes are subject to high altitudes, they are exposed to a lower barometric pressure and the physiological effects that accompany these atmospheric pressure changes can have a strong influence on their bodies and performance. Hypoxia is thought to be responsible for triggering a cascade of signaling events that eventually leads to altitude acclimatization. Acute exposure to hypoxia causes sleepiness, mental and muscle fatigue and prostration. Headache, nausea and anorexia are some of the

  18. High altitude dermatology

    Directory of Open Access Journals (Sweden)

    G K Singh

    2017-01-01

    Full Text Available Approximately, 140 million people worldwide live permanently at high altitudes (HAs and approximately another 40 million people travel to HA area (HAA every year for reasons of occupation, sports or recreation. In India, whole of Ladakh region, part of Northwest Kashmir, Northern part of Sikkim and Tenga valley of Arunachal are considered inhabited areas of HAA. The low quantity of oxygen, high exposure of ultraviolet (UV light, very low humidity, extreme subzero temperature in winter, high wind velocity, make this region difficult for lowlanders as well as for tourists. Acute mountain sickness, HA pulmonary edema, HA cerebral edema, and thromboembolic conditions are known to occur in HA. However, enough knowledge has not been shared on dermatoses peculiar to this region. Xerosis, UV-related skin disorders (tanning, photomelanosis, acute and chronic sunburn, polymorphic light eruption, chronic actinic dermatitis, actinic cheilitis, etc., cold injuries (frostbite, chilblains, acrocyanosis, erythrocyanosis, etc. nail changes (koilonychias, airborne contact dermatitis, insect bite reaction, and skin carcinoma (basal cell carcinomas, squamous cell carcinomas, and also rarely malignant melanoma are the dermatoses seen in HAAs. Early diagnosis and knowledge of HA dermatoses may prevent serious consequences of disease and improve the quality of life for the visitors as well as for native of the place.

  19. Maximal exercise and muscle oxygen extraction in acclimatizing lowlanders and high altitude natives

    DEFF Research Database (Denmark)

    Lundby, Carsten; Sander, Mikael; van Hall, Gerrit

    2006-01-01

    , and is the focus of the present study. We have studied six lowlanders during maximal exercise at sea level (SL) and with acute (AH) exposure to 4,100 m altitude, and again after 2 (W2) and 8 weeks (W8) of altitude sojourn, where also eight high altitude native (Nat) Aymaras were studied. Fractional arterial muscle...... O(2) extraction at maximal exercise was 90.0+/-1.0% in the Danish lowlanders at sea level, and remained close to this value in all situations. In contrast to this, fractional arterial O(2) extraction was 83.2+/-2.8% in the high altitude natives, and did not change with the induction of normoxia....... The capillary oxygen conductance of the lower extremity, a measure of oxygen diffusing capacity, was decreased in the Danish lowlanders after 8 weeks of acclimatization, but was still higher than the value obtained from the high altitude natives. The values were (in ml min(-1) mmHg(-1)) 55.2+/-3.7 (SL), 48...

  20. Wilderness medicine at high altitude: recent developments in the field

    Directory of Open Access Journals (Sweden)

    Shah NM

    2015-09-01

    Full Text Available Neeraj M Shah,1 Sidra Hussain,2 Mark Cooke,3 John P O’Hara,3 Adrian Mellor3,4 1Division of Asthma, Allergy and Lung Biology, King’s College London, UK; 2School of Medicine, University College London, London, UK; 3Research Institute for Sport, Physical Activity and Leisure, Leeds Beckett University, Leeds, UK; 4Academic Department of Military Anaesthesia and Critical Care, Royal Centre for Defence Medicine, Birmingham, UK Abstract: Travel to high altitude is increasingly popular. With this comes an increased incidence of high-altitude illness and therefore an increased need to improve our strategies to prevent and accurately diagnose these. In this review, we provide a summary of recent advances of relevance to practitioners who may be advising travelers to altitude. Although the Lake Louise Score is now widely used as a diagnostic tool for acute mountain sickness (AMS, increasing evidence questions the validity of doing so, and of considering AMS as a single condition. Biomarkers, such as brain natriuretic peptide, are likely correlating with pulmonary artery systolic pressure, thus potential markers of the development of altitude illness. Established drug treatments include acetazolamide, nifedipine, and dexamethasone. Drugs with a potential to reduce the risk of developing AMS include nitrate supplements, propagators of nitric oxide, and supplemental iron. The role of exercise in the development of altitude illness remains hotly debated, and it appears that the intensity of exercise is more important than the exercise itself. Finally, despite copious studies demonstrating the value of preacclimatization in reducing the risk of altitude illness and improving performance, an optimal protocol to preacclimatize an individual remains elusive. Keywords: hypoxia, acute mountain sickness, acclimatization, biomarkers, preacclimatization

  1. Physiological Changes to the Cardiovascular System at High Altitude and Its Effects on Cardiovascular Disease.

    Science.gov (United States)

    Riley, Callum James; Gavin, Matthew

    2017-06-01

    Riley, Callum James, and Matthew Gavin. Physiological changes to the cardiovascular system at high altitude and its effects on cardiovascular disease. High Alt Med Biol. 18:102-113, 2017.-The physiological changes to the cardiovascular system in response to the high altitude environment are well understood. More recently, we have begun to understand how these changes may affect and cause detriment to cardiovascular disease. In addition to this, the increasing availability of altitude simulation has dramatically improved our understanding of the physiology of high altitude. This has allowed further study on the effect of altitude in those with cardiovascular disease in a safe and controlled environment as well as in healthy individuals. Using a thorough PubMed search, this review aims to integrate recent advances in cardiovascular physiology at altitude with previous understanding, as well as its potential implications on cardiovascular disease. Altogether, it was found that the changes at altitude to cardiovascular physiology are profound enough to have a noteworthy effect on many forms of cardiovascular disease. While often asymptomatic, there is some risk in high altitude exposure for individuals with certain cardiovascular diseases. Although controlled research in patients with cardiovascular disease was largely lacking, meaning firm conclusions cannot be drawn, these risks should be a consideration to both the individual and their physician.

  2. High altitude environmental monitoring: the SHARE project and CEOP-HE

    Science.gov (United States)

    Tartari, G.

    2009-04-01

    Mountain areas above 2,500 m a.s.l. constitute about 25% of the Earth's surface and play a fundamental role in the global water balance, while influencing global climate and atmospheric circulation systems. Several millions, including lowlanders, are directly affected by the impacts of climate change on glaciers and water resource distribution. Mountains and high altitude plateaus are subject to the highest rate of temperature increase (e.g., Tibetan Plateau) and are recognized as particularly vulnerable to the effects of climate change. In spite of this, the number of permanent monitoring sites in the major environmental networks decreases with altitude. On a sample of two hundred high altitude automatic weather stations located above 2,500 m a.s.l., less than 20% are over 4,000 m, while there are only 24 stations in the world that could be considered "complete" high altitude observatories. Furthermore, entire mountain areas are left uncovered, creating significant data gaps which make reliable modelling and forecasting nearly impossible. In response to these problems, Ev-K2-CNR has developed the project SHARE (Stations at High Altitude for Research on the Environment) with the support of the Italian government and in collaboration with UNEP. This integrated environmental monitoring and research project aims to improve knowledge on the local, regional and global consequences of climate change in mountain regions and on the influence of high elevations on climate, atmospheric circulation and hydrology. SHARE today boasts a network of 13 permanent monitoring stations between 2,165 m and 8,000 m. Affiliated researchers have produced over 150 scientific publications in atmospheric sciences, meteorology and climate, glaciology, limnology and paleolimnology and geophysics. SHARE network data is also contributed to international programs (UNEP-ABC, WMO-GAW, WCRP-GEWEX-CEOP, NASA-AERONET, ILTER, EU-EUSAAR, EU-ACCENT). Within this context, the CEOP-High Elevations (CEOP

  3. Turbojet Performance and Operation at High Altitudes with Hydrogen and Jp-4 Fuels

    Science.gov (United States)

    Fleming, W A; Kaufman, H R; Harp, J L , Jr; Chelko, L J

    1956-01-01

    Two current turbojet engines were operated with gaseous-hydrogen and JP-4 fuels at very high altitudes and a simulated Mach number of 0.8. With gaseous hydrogen as the fuel stable operation was obtained at altitudes up to the facility limit of about 90,000 feet and the specific fuel consumption was only 40 percent of that with JP-4 fuel. With JP-4 as the fuel combustion was unstable at altitudes above 60,000 to 65,000 feet and blowout limits were reached at 75,000 to 80,000 feet. Over-all performance, component efficiencies, and operating range were reduced considerable at very high altitudes with both fuels.

  4. Metabolic characteristics and response to high altitude in Phrynocephalus erythrurus (Lacertilia: Agamidae, a lizard dwell at altitudes higher than any other living lizards in the world.

    Directory of Open Access Journals (Sweden)

    Xiaolong Tang

    Full Text Available Metabolic response to high altitude remains poorly explored in reptiles. In the present study, the metabolic characteristics of Phrynocephaluserythrurus (Lacertilia: Agamidae, which inhabits high altitudes (4500 m and Phrynocephalusprzewalskii (Lacertilia: Agamidae, which inhabits low altitudes, were analysed to explore the metabolic regulatory strategies for lizards living at high-altitude environments. The results indicated that the mitochondrial respiratory rates of P. erythrurus were significantly lower than those of P. przewalskii, and that proton leak accounts for 74~79% of state 4 and 7~8% of state3 in P. erythrurus vs. 43~48% of state 4 and 24~26% of state3 in P. przewalskii. Lactate dehydrogenase (LDH activity in P. erythrurus was lower than in P. przewalskii, indicating that at high altitude the former does not, relatively, have a greater reliance on anaerobic metabolism. A higher activity related to β-hydroxyacyl coenzyme A dehydrogenase (HOAD and the HOAD/citrate synthase (CS ratio suggested there was a possible higher utilization of fat in P. erythrurus. The lower expression of PGC-1α and PPAR-γ in P. erythrurus suggested their expression was not influenced by cold and low PO2 at high altitude. These distinct characteristics of P. erythrurus are considered to be necessary strategies in metabolic regulation for living at high altitude and may effectively compensate for the negative influence of cold and low PO2.

  5. The GRAD high-altitude balloon flight over Antarctica

    International Nuclear Information System (INIS)

    Eichhorn, G.; Coldwell, R.L.; Dunnam, F.E.; Rester, A.C.; Trombka, J.I.; Starr, R.; Lasche, G.P.

    1989-01-01

    The Gamma Ray Advanced Detector(GRAD) consists of a n-type germanium detector inside an active bismuth-germanate Compton and charged particle shield with additional active plastic shielding across the aperture. It will be flown on a high altitude balloon at 36 km altitude at a latitude of 78 degree S over Antarctica for observations of gamma radiation emitted by the radioactive decay of 56 Co in the Supernova SN1987A, for assessment of the performance of bismuth-germanate scintillation material in the radiation environment of near space, for gathering information on the gamma-ray background over Antarctica, and for testing fault-tolerant software

  6. Qualitative evaluations and comparisons of six night-vision colorization methods

    Science.gov (United States)

    Zheng, Yufeng; Reese, Kristopher; Blasch, Erik; McManamon, Paul

    2013-05-01

    Current multispectral night vision (NV) colorization techniques can manipulate images to produce colorized images that closely resemble natural scenes. The colorized NV images can enhance human perception by improving observer object classification and reaction times especially for low light conditions. This paper focuses on the qualitative (subjective) evaluations and comparisons of six NV colorization methods. The multispectral images include visible (Red-Green- Blue), near infrared (NIR), and long wave infrared (LWIR) images. The six colorization methods are channel-based color fusion (CBCF), statistic matching (SM), histogram matching (HM), joint-histogram matching (JHM), statistic matching then joint-histogram matching (SM-JHM), and the lookup table (LUT). Four categries of quality measurements are used for the qualitative evaluations, which are contrast, detail, colorfulness, and overall quality. The score of each measurement is rated from 1 to 3 scale to represent low, average, and high quality, respectively. Specifically, high contrast (of rated score 3) means an adequate level of brightness and contrast. The high detail represents high clarity of detailed contents while maintaining low artifacts. The high colorfulness preserves more natural colors (i.e., closely resembles the daylight image). Overall quality is determined from the NV image compared to the reference image. Nine sets of multispectral NV images were used in our experiments. For each set, the six colorized NV images (produced from NIR and LWIR images) are concurrently presented to users along with the reference color (RGB) image (taken at daytime). A total of 67 subjects passed a screening test ("Ishihara Color Blindness Test") and were asked to evaluate the 9-set colorized images. The experimental results showed the quality order of colorization methods from the best to the worst: CBCF colorization and for quantitative evaluation using an objective metric such as objective evaluation index

  7. The Optical/Near-infrared Extinction Law in Highly Reddened Regions

    Science.gov (United States)

    Hosek, Matthew W., Jr.; Lu, Jessica R.; Anderson, Jay; Do, Tuan; Schlafly, Edward F.; Ghez, Andrea M.; Clarkson, William I.; Morris, Mark R.; Albers, Saundra M.

    2018-03-01

    A precise extinction law is a critical input when interpreting observations of highly reddened sources such as young star clusters and the Galactic Center (GC). We use Hubble Space Telescope observations of a region of moderate extinction and a region of high extinction to measure the optical and near-infrared extinction law (0.8–2.2 μm). The moderate-extinction region is the young massive cluster Westerlund 1 (Wd1; A Ks ∼ 0.6 mag), where 453 proper-motion selected main-sequence stars are used to measure the shape of the extinction law. To quantify the shape, we define the parameter {{ \\mathcal S }}1/λ , which behaves similarly to a color-excess ratio, but is continuous as a function of wavelength. The high-extinction region is the GC (A Ks ∼ 2.5 mag), where 819 red clump stars are used to determine the normalization of the law. The best-fit extinction law is able to reproduce the Wd1 main-sequence colors, which previous laws misestimate by 10%–30%. The law is inconsistent with a single power law, even when only the near-infrared filters are considered, and has A F125W/A Ks and A F814W/A Ks values that are 18% and 24% higher than the commonly used Nishiyama et al. law, respectively. Using this law, we recalculate the Wd1 distance to be 3905 ± 422 pc from published observations of the eclipsing binary W13. This new extinction law should be used for highly reddened populations in the Milky Way, such as the Quintuplet cluster and Young Nuclear Cluster. A python code is provided to generate the law for future use.

  8. Coca: High Altitude Remedy of the Ancient Incas.

    Science.gov (United States)

    Biondich, Amy Sue; Joslin, Jeremy D

    2015-12-01

    The use of coca leaf for medicinal purposes is a centuries-old tradition of the native peoples of South America. Coca products are thought by many laypersons to provide risk-free benefits to users participating in strenuous activities at high altitude. Physiologic studies of coca have increased understanding of its possible mechanism of action as well as its potential impact on high altitude activities. This present work explores the role of coca throughout the history of the Andean peoples and explores whether this ancient remedy has a place in modern medicine. A focused summary of research articles with particular relevance to the field of wilderness medicine is also included to better provide the reader with lessons not only from history but also from another culture. Copyright © 2015 Wilderness Medical Society. Published by Elsevier Inc. All rights reserved.

  9. White Mountain Research Station: 25 years of high-altitude research. [organization and functions of test facility for high altitude research

    Science.gov (United States)

    Pace, N.

    1973-01-01

    The organization and functions of a test facility for conducting research projects at high altitudes are discussed. The projects conducted at the facility include the following: (1) bird physiology, (2) cardiorespiratory physiology, (3) endocrinological studies, (4) neurological studies, (5) metabolic studies, and (6) geological studies.

  10. THE ORIGIN OF COLOR GRADIENTS IN EARLY-TYPE SYSTEMS AND THEIR COMPACTNESS AT HIGH-z

    International Nuclear Information System (INIS)

    La Barbera, F.; De Carvalho, R. R.

    2009-01-01

    In this Letter, we present mean optical+NIR color gradient estimates for 5080 early-type galaxies (ETGs) in the grizY JHK wavebands of the Sloan Digital Sky Survey plus the UKIRT Infrared Deep Sky Survey. The color gradient is estimated as the logarithmic slope of the radial color profile in ETGs. With such a large sample size, we study the variation of the mean color gradient as a function of waveband with unprecedented accuracy. We find that (1) color gradients are mainly due, on average, to a metallicity variation of about -0.4 dex per decade in galaxy radius; and (2) a small, but significant, positive age gradient is present, on average, in ETGs, with the inner stellar population being slightly younger, by ∼0.1 dex per radial decade, than the outer one. Also, we show that the presence of a positive mean age gradient in ETGs, as found in the present study, implies their effective radius to be smaller at high-z, consistent with observations.

  11. High Altitude Warfare: The Kargil Conflict and the Future

    National Research Council Canada - National Science Library

    Acosta, Marcus

    2003-01-01

    The unique combination of thin air, freezing temperatures, and mountainous terrain that forms the high altitude environment has resisted advances in military technology for centuries, The emergence...

  12. Lens autofluorescence is not increased at high altitude

    DEFF Research Database (Denmark)

    Kessel, Line; Kofoed, Peter Kristian; Zubieta-Calleja, Gustavo

    2010-01-01

    in Denmark. RESULTS: No significant differences in lens fluorescence or transmittance were found between Bolivian and Danish volunteers. CONCLUSION: Age-corrected lens fluorescence and transmittance were comparable for healthy participants living at high altitude near the equator and healthy volunteers...

  13. Solar Cell Short Circuit Current Errors and Uncertainties During High Altitude Calibrations

    Science.gov (United States)

    Snyder, David D.

    2012-01-01

    High altitude balloon based facilities can make solar cell calibration measurements above 99.5% of the atmosphere to use for adjusting laboratory solar simulators. While close to on-orbit illumination, the small attenuation to the spectra may result in under measurements of solar cell parameters. Variations of stratospheric weather, may produce flight-to-flight measurement variations. To support the NSCAP effort, this work quantifies some of the effects on solar cell short circuit current (Isc) measurements on triple junction sub-cells. This work looks at several types of high altitude methods, direct high altitude meas urements near 120 kft, and lower stratospheric Langley plots from aircraft. It also looks at Langley extrapolation from altitudes above most of the ozone, for potential small balloon payloads. A convolution of the sub-cell spectral response with the standard solar spectrum modified by several absorption processes is used to determine the relative change from AMO, lscllsc(AMO). Rayleigh scattering, molecular scatterin g from uniformly mixed gases, Ozone, and water vapor, are included in this analysis. A range of atmosph eric pressures are examined, from 0. 05 to 0.25 Atm to cover the range of atmospheric altitudes where solar cell calibrations a reperformed. Generally these errors and uncertainties are less than 0.2%

  14. Right ventricular morphology and function in chronic obstructive pulmonary disease patients living at high altitude.

    Science.gov (United States)

    Güvenç, Tolga Sinan; Erer, Hatice Betül; Kul, Seref; Perinçek, Gökhan; Ilhan, Sami; Sayar, Nurten; Yıldırım, Binnaz Zeynep; Doğan, Coşkun; Karabağ, Yavuz; Balcı, Bahattin; Eren, Mehmet

    2013-01-01

    Pulmonary vasculature is affected in patients with chronic pulmonary obstructive disease (COPD). As a result of increased pulmonary resistance, right ventricular morphology and function are altered in COPD patients. High altitude and related hypoxia causes pulmonary vasoconstriction, thereby affecting the right ventricle. We aimed to investigate the combined effects of COPD and altitude-related chronic hypoxia on right ventricular morphology and function. Forty COPD patients living at high altitude (1768 m) and 41 COPD patients living at sea level were enrolled in the study. All participants were diagnosed as COPD by a pulmonary diseases specialist depending on symptoms, radiologic findings and pulmonary function test results. Detailed two-dimensional echocardiography was performed by a cardiologist at both study locations. Oxygen saturation and mean pulmonary artery pressure were higher in the high altitude group. Right ventricular end diastolic diameter, end systolic diameter, height and end systolic area were significantly higher in the high altitude group compared to the sea level group. Parameters of systolic function, including tricuspid annular systolic excursion, systolic velocity of tricuspid annulus and right ventricular isovolumic acceleration were similar between groups, while fractional area change was significantly higher in the sea level groups compared to the high altitude group. Indices of diastolic function and myocardial performance index were similar between groups. An increase in mean pulmonary artery pressure and right ventricular dimensions are observed in COPD patients living at high altitude. Despite this increase, systolic and diastolic functions of the right ventricle, as well as global right ventricular performance are similar in COPD patients living at high altitude and sea level. Altitude-related adaptation to chronic hypoxia could explain these findings. Copyright © 2012 Australian and New Zealand Society of Cardiac and Thoracic

  15. High altitude and hemoglobin function in the vultures Gyps rueppelli and Aegypius monachus

    DEFF Research Database (Denmark)

    Weber, Roy E.; Hiebl, Inge; Braunitzer, Gerhard

    1988-01-01

    Functional characteristics of the stripped composite hemoglobins (Hbs) of lhevultures Gyps rueppellii and Aegypills monachus that can fly at extremely high altitudes, and of component Hbs of G. rueppellii are reported, in relation to influences of pH, temperalure and inositol hexaphosphate. G...... structures of the constituent polypeptide chains to trace molecular adaptations to high-altitude respiration, and to physiological factors (pulmonary hypoxia and hypocapnia, body temperature shifts, and lung and nasal gas and heat exchange) to discern their possible survival value at altitudes of 11300 m....

  16. Natural-color and color-infrared image mosaics of the Colorado River corridor in Arizona derived from the May 2009 airborne image collection

    Science.gov (United States)

    Davis, Philip A.

    2013-01-01

    -processing software. The tiff world files (tfw) are provided, even though they are generally not needed for most software to read an embedded geotiff image. All image data are projected in the State Plane (SP) map projection using the central Arizona zone (202) and the North American Datum of 1983 (NAD83). The map-tile scheme used to segment the corridor image mosaic followed the standard USGS quarter-quadrangle (QQ) map borders, but the high resolution (20 cm) of the images required further quarter segmentation (QQQ) of the standard QQ tiles, where the image mosaic covered a large fraction of a QQ map tile (segmentation shown in (figure 6), where QQ_1 to QQ_4 shows the number convention used to designate a quarter of a QQ tile). To minimize the size of each image tile, each image or map tile was subset to only include that part of the tile that had image data. In addition, some QQQ image tiles within a QQ tile were combined when adjacent QQQ map tiles were small. Thus, some image tiles consist of combinations of QQQ map tiles, some consist of an entire QQ map tile, and some consist of two adjoining QQ map tiles. The final image tiles number 143, which is a large number of files to list on the Internet for both the natural-color and color-infrared images. Thus, the image tiles were placed in seven file folders based on the one-half-degree geographic boundaries within the study area (fig. 7). The map tiles in each file folder were compressed to minimize folder size for more efficient downloading. The file folders are sequentially referred to as zone 1 through zone 7, proceeding down river (fig. 7). The QQ designations of the image tiles contained within each folder or zone are shown on the index map for each respective zone (figs. 8–14).

  17. The effectiveness of a near-infrared vascular imaging device to support intravenous cannulation in children with dark skin color : a cluster randomized clinical trial

    NARCIS (Netherlands)

    van der Woude, Olga C P; Cuper, Natascha J; Getrouw, Chavalleh; Kalkman, Cor J; de Graaff, Jurgen C

    BACKGROUND: Poor vein visibility can make IV cannulation challenging in children with dark skin color. In the operating room, we studied the effectiveness of a near-infrared vascular imaging device (VascuLuminator) to facilitate IV cannulation in children with dark skin color. METHODS: In the

  18. Nutritional Strategies for the Preservation of Fat Free Mass at High Altitude

    Directory of Open Access Journals (Sweden)

    Stacie L. Wing-Gaia

    2014-02-01

    Full Text Available Exposure to extreme altitude presents many physiological challenges. In addition to impaired physical and cognitive function, energy imbalance invariably occurs resulting in weight loss and body composition changes. Weight loss, and in particular, loss of fat free mass, combined with the inherent risks associated with extreme environments presents potential performance, safety, and health risks for those working, recreating, or conducting military operations at extreme altitude. In this review, contributors to muscle wasting at altitude are highlighted with special emphasis on protein turnover. The article will conclude with nutritional strategies that may potentially attenuate loss of fat free mass during high altitude exposure.

  19. CONSTRAINING DUST AND COLOR VARIATIONS OF HIGH-z SNe USING NICMOS ON THE HUBBLE SPACE TELESCOPE

    International Nuclear Information System (INIS)

    Nobili, S.; Amanullah, R.; Goobar, A.

    2009-01-01

    We present data from the Supernova Cosmology Project for five high redshift Type Ia supernovae (SNe Ia) that were obtained using the NICMOS infrared camera on the Hubble Space Telescope. We add two SNe from this sample to a rest-frame I-band Hubble diagram, doubling the number of high redshift supernovae on this diagram. This I-band Hubble diagram is consistent with a flat universe (Ω M , Ω Λ ) = (0.29, 0.71). A homogeneous distribution of large grain dust in the intergalactic medium (replenishing dust) is incompatible with the data and is excluded at the 5σ confidence level, if the SN host galaxy reddening is corrected assuming R V = 1.75. We use both optical and infrared observations to compare photometric properties of distant SNe Ia with those of nearby objects. We find generally good agreement with the expected color evolution for all SNe except the highest redshift SN in our sample (SN 1997ek at z = 0.863) which shows a peculiar color behavior. We also present spectra obtained from ground-based telescopes for type identification and determination of redshift.

  20. Iron supplementation at high altitudes induces inflammation and oxidative injury to lung tissues in rats

    Energy Technology Data Exchange (ETDEWEB)

    Salama, Samir A., E-mail: salama.3@buckeyemail.osu.edu [High Altitude Research Center, Taif University, Al-Haweiah, Taif 21974 (Saudi Arabia); Department of Biochemistry, Faculty of Pharmacy, Al-Azhar University, Cairo 11751 (Egypt); Department of Pharmacology and GTMR Unit, College of Clinical Pharmacy, Taif University, Al-Haweiah, Taif 21974 (Saudi Arabia); Omar, Hany A. [Department of Pharmacology, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62514 (Egypt); Maghrabi, Ibrahim A. [Department of Clinical Pharmacy, College of Clinical Pharmacy, Taif University, Al-Haweiah, Taif 21974 (Saudi Arabia); AlSaeed, Mohammed S. [Department of Surgery, College of Medicine, Taif University, Al-Haweiah, Taif 21974 (Saudi Arabia); EL-Tarras, Adel E. [High Altitude Research Center, Taif University, Al-Haweiah, Taif 21974 (Saudi Arabia)

    2014-01-01

    Exposure to high altitudes is associated with hypoxia and increased vulnerability to oxidative stress. Polycythemia (increased number of circulating erythrocytes) develops to compensate the high altitude associated hypoxia. Iron supplementation is, thus, recommended to meet the demand for the physiological polycythemia. Iron is a major player in redox reactions and may exacerbate the high altitudes-associated oxidative stress. The aim of this study was to explore the potential iron-induced oxidative lung tissue injury in rats at high altitudes (6000 ft above the sea level). Iron supplementation (2 mg elemental iron/kg, once daily for 15 days) induced histopathological changes to lung tissues that include severe congestion, dilatation of the blood vessels, emphysema in the air alveoli, and peribronchial inflammatory cell infiltration. The levels of pro-inflammatory cytokines (IL-1β, IL-6, and TNF-α), lipid peroxidation product and protein carbonyl content in lung tissues were significantly elevated. Moreover, the levels of reduced glutathione and total antioxidant capacity were significantly reduced. Co-administration of trolox, a water soluble vitamin E analog (25 mg/kg, once daily for the last 7 days of iron supplementation), alleviated the lung histological impairments, significantly decreased the pro-inflammatory cytokines, and restored the oxidative stress markers. Together, our findings indicate that iron supplementation at high altitudes induces lung tissue injury in rats. This injury could be mediated through excessive production of reactive oxygen species and induction of inflammatory responses. The study highlights the tissue injury induced by iron supplementation at high altitudes and suggests the co-administration of antioxidants such as trolox as protective measures. - Highlights: • Iron supplementation at high altitudes induced lung histological changes in rats. • Iron induced oxidative stress in lung tissues of rats at high altitudes. • Iron

  1. Iron supplementation at high altitudes induces inflammation and oxidative injury to lung tissues in rats

    International Nuclear Information System (INIS)

    Salama, Samir A.; Omar, Hany A.; Maghrabi, Ibrahim A.; AlSaeed, Mohammed S.; EL-Tarras, Adel E.

    2014-01-01

    Exposure to high altitudes is associated with hypoxia and increased vulnerability to oxidative stress. Polycythemia (increased number of circulating erythrocytes) develops to compensate the high altitude associated hypoxia. Iron supplementation is, thus, recommended to meet the demand for the physiological polycythemia. Iron is a major player in redox reactions and may exacerbate the high altitudes-associated oxidative stress. The aim of this study was to explore the potential iron-induced oxidative lung tissue injury in rats at high altitudes (6000 ft above the sea level). Iron supplementation (2 mg elemental iron/kg, once daily for 15 days) induced histopathological changes to lung tissues that include severe congestion, dilatation of the blood vessels, emphysema in the air alveoli, and peribronchial inflammatory cell infiltration. The levels of pro-inflammatory cytokines (IL-1β, IL-6, and TNF-α), lipid peroxidation product and protein carbonyl content in lung tissues were significantly elevated. Moreover, the levels of reduced glutathione and total antioxidant capacity were significantly reduced. Co-administration of trolox, a water soluble vitamin E analog (25 mg/kg, once daily for the last 7 days of iron supplementation), alleviated the lung histological impairments, significantly decreased the pro-inflammatory cytokines, and restored the oxidative stress markers. Together, our findings indicate that iron supplementation at high altitudes induces lung tissue injury in rats. This injury could be mediated through excessive production of reactive oxygen species and induction of inflammatory responses. The study highlights the tissue injury induced by iron supplementation at high altitudes and suggests the co-administration of antioxidants such as trolox as protective measures. - Highlights: • Iron supplementation at high altitudes induced lung histological changes in rats. • Iron induced oxidative stress in lung tissues of rats at high altitudes. • Iron

  2. Effects of erythrocyte infusion on VO2max at high altitude

    DEFF Research Database (Denmark)

    Young, Jette Feveile; Sawka, M N; Muza, S R

    1996-01-01

    This study investigated whether autologous erythrocyte infusion would ameliorate the decrement in maximal O2 uptake (VO2max) experienced by lowlanders when they ascend to high altitude. VO2max was measured in 16 men (treadmill running) at sea level (SL) and on the 1st (HA1) and 9th (HA9) days...... of high-altitude (4,300 m) residence. After VO2max was measured at SL, subjects were divided into two matched groups (n = 8). Twenty-four hours before ascent to high altitude, the experimental group received a 700-ml infusion of autologous erythrocytes and saline (42% hematocrit), whereas the control...... group received only saline. The VO2max of erythrocyte-infused [54 +/- 1 (SE) ml.kg-1.min-1] and control subjects (52 +/- 2 ml.kg-1.min-1) did not differ at SL before infusion. The decrement in VO2max on HA1 did not differ between groups, averaging 26% overall, despite higher (P

  3. Natural Selection on Genes Related to Cardiovascular Health in High-Altitude Adapted Andeans.

    Science.gov (United States)

    Crawford, Jacob E; Amaru, Ricardo; Song, Jihyun; Julian, Colleen G; Racimo, Fernando; Cheng, Jade Yu; Guo, Xiuqing; Yao, Jie; Ambale-Venkatesh, Bharath; Lima, João A; Rotter, Jerome I; Stehlik, Josef; Moore, Lorna G; Prchal, Josef T; Nielsen, Rasmus

    2017-11-02

    The increase in red blood cell mass (polycythemia) due to the reduced oxygen availability (hypoxia) of residence at high altitude or other conditions is generally thought to be beneficial in terms of increasing tissue oxygen supply. However, the extreme polycythemia and accompanying increased mortality due to heart failure in chronic mountain sickness most likely reduces fitness. Tibetan highlanders have adapted to high altitude, possibly in part via the selection of genetic variants associated with reduced polycythemic response to hypoxia. In contrast, high-altitude-adapted Quechua- and Aymara-speaking inhabitants of the Andean Altiplano are not protected from high-altitude polycythemia in the same way, yet they exhibit other adaptive features for which the genetic underpinnings remain obscure. Here, we used whole-genome sequencing to scan high-altitude Andeans for signals of selection. The genes showing the strongest evidence of selection-including BRINP3, NOS2, and TBX5-are associated with cardiovascular development and function but are not in the response-to-hypoxia pathway. Using association mapping, we demonstrated that the haplotypes under selection are associated with phenotypic variations related to cardiovascular health. We hypothesize that selection in response to hypoxia in Andeans could have vascular effects and could serve to mitigate the deleterious effects of polycythemia rather than reduce polycythemia itself. Copyright © 2017. Published by Elsevier Inc.

  4. The use of LANDSAT-1 imagery in mapping and managing soil and range resources in the Sand Hills region of Nebraska

    Science.gov (United States)

    Seevers, P. M. (Principal Investigator); Drew, J. V.

    1976-01-01

    The author has identified the following significant results. Evaluation of ERTS-1 imagery for the Sand Hills region of Nebraska has shown that the data can be used to effectively measure several parameters of inventory needs. (1) Vegetative biomass can be estimated with a high degree of confidence using computer compatable tape data. (2) Soils can be mapped to the subgroup level with high altitude aircraft color infrared photography and to the association level with multitemporal ERTS-1 imagery. (3) Water quality in Sand Hills lakes can be estimated utilizing computer compatable tape data. (4) Center pivot irrigation can be inventoried from satellite data and can be monitored regarding site selection and relative success of establishment from high altitude aircraft color infrared photography. (5) ERTS-1 data is of exceptional value in wide-area inventory of natural resource data in the Sand Hills region of Nebraska.

  5. Thoracic skeletal morphology and high-altitude hypoxia in Andean prehistory.

    Science.gov (United States)

    Weinstein, Karen J

    2007-09-01

    Living humans from the highland Andes exhibit antero-posteriorly and medio-laterally enlarged chests in response to high-altitude hypoxia. This study hypothesizes that morphological responses to high-altitude hypoxia should also be evident in pre-Contact Andean groups. Thoracic skeletal morphology in four groups of human skeletons (N = 347) are compared: two groups from coastal regions (Ancón, Peru, n = 79 and Arica, Chile, n = 123) and two groups from high altitudes (San Pedro de Atacama, Chile, n = 102 and Machu Picchu and Cuzco, Peru, n = 43). Osteometric variables that represent proportions of chest width and depth include sternal and clavicular lengths and breadths and rib length, curvature, and area. Each variable was measured relative to body size, transformed into logarithmic indices, and compared across sex-specific groups using ANOVA and Tukey multiple comparison tests. Atacama highlanders have the largest sternal and clavicular proportions and ribs with the greatest area and least amount of curvature, features that suggest an antero-posteriorly deep and mediolaterally wide thoracic skeleton. Ancón lowlanders exhibit proportions indicating narrower and shallower chests. Machu Picchu and Cuzco males cluster with the other highland group in rib curvature and area at the superior levels of the thorax, whereas chest proportions in Machu Picchu and Cuzco females resemble those of lowlanders. The variation in Machu Picchu and Cuzco males and females is interpreted as the result of population migrations. The presence of morphological traits indicative of enlarged chests in some highland individuals suggests that high-altitude hypoxia was an environmental stressor shaping the biology of highland Andean groups during the pre-Contact period. (c) 2007 Wiley-Liss, Inc.

  6. Identification of color development potential of quartz by Raman spectroscopy

    International Nuclear Information System (INIS)

    Alkmim, Danielle G.; Lameiras, Fernando S.; Almeida, Frederico O.T.

    2013-01-01

    Colorless quartz is usually exposed to ionizing radiation (gamma rays or high energy electron beams) to acquire different colors for jewelry. Color development is due to the presence of traces of some elements such as aluminum, iron, hydrogen, lithium, or sodium. Most quartz crystals are extracted colorless from nature and it is necessary to separate those that can develop colors from those that cannot. Irradiation tests can be used to accomplish this separation, but they take a long time. Infrared signature of colorless quartz can also be used. However, infrared spectroscopy is quite expensive, especially when using portable devices. Raman spectroscopy is now available as an inexpensive and portable technique that could provide identification of the samples of colorless quartz still in the field, facilitating the prediction for their economic exploitation. In addition, Raman spectroscopy usually requires a minimum or no sample preparation. This paper presents an investigation of the feasibility of using Raman spectroscopy as a substitute for infrared spectroscopy to predict the potential for color development of quartz. A band at 3595 cm -1 in the Raman shift spectrum was observed only along the c axis of a prasiolite excited by a high power 514 nm laser. This band was not observed in quartz samples that do not develop color after irradiation. Further studies are required to identify the potential for color development by Raman spectroscopy of other types of colorless quartz. (author)

  7. Metabolic Effects of High Altitude Trekking in Patients With Type 2 Diabetes

    NARCIS (Netherlands)

    de Mol, Pieter; Fokkert, Marion J.; de Vries, Suzanna T.; de Koning, Eelco J. P.; Dikkeschei, Bert D.; Gans, Rijnold O. B.; Tack, Cees J.; Bilo, Henk J. G.

    2012-01-01

    OBJECTIVE-Limited information is available regarding the metabolic effects of high altitude trekking in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS-Thirteen individuals with type 2 diabetes took part, in a 12-day expedition to the summit of Mount Toubkal (altitude, 4,167 m), Morocco,

  8. Metabolic effects of high altitude trekking in patients with type 2 diabetes

    NARCIS (Netherlands)

    Mol, P. de; Fokkert, M.J.; Vries, S.T. de; Koning, E.J. de; Dikkeschei, B.D.; Gans, R.O.; Tack, C.J.J.; Bilo, H.J.

    2012-01-01

    OBJECTIVE Limited information is available regarding the metabolic effects of high altitude trekking in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS Thirteen individuals with type 2 diabetes took part in a 12-day expedition to the summit of Mount Toubkal (altitude, 4,167 m), Morocco,

  9. Hyperbaric oxygen preconditioning protects against traumatic brain injury at high altitude.

    Science.gov (United States)

    Hu, S L; Hu, R; Li, F; Liu, Z; Xia, Y Z; Cui, G Y; Feng, H

    2008-01-01

    Recent studies have shown that preconditioning with hyperbaric oxygen (HBO) can reduce ischemic and hemorrhagic brain injury. We investigated effects of HBO preconditioning on traumatic brain injury (TBI) at high altitude and examined the role of matrix metalloproteinase-9 (MMP-9) in such protection. Rats were randomly divided into 3 groups: HBO preconditioning group (HBOP; n = 13), high-altitude group (HA; n = 13), and high-altitude sham operation group (HASO; n = 13). All groups were subjected to head trauma by weight-drop device, except for HASO group. HBOP rats received 5 sessions of HBO preconditioning (2.5 ATA, 100% oxygen, 1 h daily) and then were kept in hypobaric chamber at 0.6 ATA (to simulate pressure at 4000m altitude) for 3 days before operation. HA rats received control pretreatment (1 ATA, room air, 1 h daily), then followed the same procedures as HBOP group. HASO rats were subjected to skull opening only without brain injury. Twenty-four hours after TBI, 7 rats from each group were examined for neurological function and brain water content; 6 rats from each group were killed for analysis by H&E staining and immunohistochemistry. Neurological outcome in HBOP group (0.71 +/- 0.49) was better than HA group (1.57 +/- 0.53; p < 0.05). Preconditioning with HBO significantly reduced percentage of brain water content (86.24 +/- 0.52 vs. 84.60 +/- 0.37; p < 0.01). Brain morphology and structure seen by light microscopy was diminished in HA group, while fewer pathological injuries occurred in HBOP group. Compared to HA group, pretreatment with HBO significantly reduced the number of MMP-9-positive cells (92.25 +/- 8.85 vs. 74.42 +/- 6.27; p < 0.01). HBO preconditioning attenuates TBI in rats at high altitude. Decline in MMP-9 expression may contribute to HBO preconditioning-induced protection of brain tissue against TBI.

  10. Increased Cardiometabolic Risk and Worsening Hypoxemia at High Altitude.

    Science.gov (United States)

    Miele, Catherine H; Schwartz, Alan R; Gilman, Robert H; Pham, Luu; Wise, Robert A; Davila-Roman, Victor G; Jun, Jonathan C; Polotsky, Vsevolod Y; Miranda, J Jaime; Leon-Velarde, Fabiola; Checkley, William

    2016-06-01

    Miele, Catherine H., Alan R. Schwartz, Robert H. Gilman, Luu Pham, Robert A. Wise, Victor G. Davila-Roman, Jonathan C. Jun, Vsevolod Y. Polotsky, J. Jaime Miranda, Fabiola Leon-Velarde, and William Checkley. Increased cardiometabolic risk and worsening hypoxemia at high altitude. High Alt Med Biol. 17:93-100, 2016.-Metabolic syndrome, insulin resistance, diabetes, and dyslipidemia are associated with an increased risk of cardiovascular disease. While excessive erythrocytosis is associated with cardiovascular complications, it is unclear how worsening hypoxemia of any degree affects cardiometabolic risk factors in high-altitude populations. We studied the relationship between daytime resting oxyhemoglobin saturation and cardiometabolic risk factors in adult participants living in Puno, Peru (3825 m above sea level). We used multivariable logistic regression models to study the relationship between having a lower oxyhemoglobin saturation and markers of cardiometabolic risk. Nine hundred and fifty-four participants (mean age 55 years, 52% male) had information available on pulse oximetry and markers of cardiometabolic risk. Average oxyhemoglobin saturation was 90% (interquartile range 88%-92%) and 43 (4.5%) had excessive erythrocytosis. Older age, decreased height-adjusted lung function, and higher body mass index (BMI) were associated with having an oxyhemoglobin saturation ≤85%. When adjusting for age, sex, socioeconomic status, having excessive erythrocytosis, and site, we found that each 5% decrease in oxyhemoglobin saturation was associated with a higher adjusted odds of metabolic syndrome (OR = 1.35, 95% CI: 1.07-1.72, p 2 mass units (OR = 1.29, 95% CI: 1.00-1.67, p < 0.05), hemoglobin A1c ≥6.5% (OR = 1.66, 95% CI: 1.09-2.51, p < 0.04), and high sensitivity C-reactive protein (hs-CRP) ≥3 mg/L (OR = 1.46, 95% CI: 1.09-1.96, p < 0.01). In high-altitude populations in Puno, Peru, a higher BMI and lower pulmonary function were

  11. Systems Design and Experimental Evaluation of a High-Altitude Relight Test Facility

    Science.gov (United States)

    Paxton, Brendan

    Novel advances in gas turbine engine combustor technology, led by endeavors into fuel efficiency and demanding environmental regulations, have been fraught with performance and safety concerns. While the majority of low emissions gas turbine engine combustor technology has been necessary for power generation applications, the push for ultra-low NOx combustion in aircraft jet engines has been ever present. Recent state-of-the-art combustor designs notably tackle historic emissions challenges by operating at fuel-lean conditions, which are characterized by an increase in the amount of air flow sent to the primary combustion zone. While beneficial in reducing NOx emissions, the fuel-lean mechanisms that characterize these combustor designs rely heavily upon high-energy and high-velocity air flows to sufficiently mix and atomize fuel droplets, ultimately leading to flame stability concerns during low-power operation. When operating at high-altitude conditions, these issues are further exacerbated by the presence of low ambient air pressures and temperatures, which can lead to engine flame-out situations and hamper engine relight attempts. To aid academic and industrial research ventures into improving the high-altitude lean blow-out and relight performance of modern gas turbine engine combustor technologies, the High-Altitude Relight Test Facility (HARTF) was designed and constructed at the University of Cincinnati (UC) Combustion and Fire Research Laboratory (CFRL). Following its construction, an experimental evaluation of its abilities to facilitate optically-accessible ignition, combustion, and spray testing for gas turbine engine combustor hardware at simulated high-altitude conditions was performed. In its evaluation, performance limit references were established through testing of the HARTF vacuum and cryogenic air-chilling capabilities. These tests were conducted with regard to end-user control---the creation and the maintenance of a realistic high-altitude

  12. ACUTE PHASE PROTEIN INCREASE IN HIGH ALTITUDE MOUNTAINEERS

    Directory of Open Access Journals (Sweden)

    Tolga Saka

    Full Text Available ABSTRACT Introduction: Many middle-aged Turks go hiking in mountains to breathe some fresh air or to maintain fitness. Objective: This study investigated the effects of regular high altitude mountain climbing on the metabolic and hematological responses of mountaineers. Methods: Hematological and biochemical parameters were studied, as well as some hormonal values of 21 mountaineers and 16 healthy age-matched sedentary volunteers. Results: The neutrophil to lymphocyte ratio (NLR was significantly lower (p<0.04 in mountaineers compared with the sedentary group. Total protein (p<0.001 and albumin (p<0.001 were lower, while the levels of ferritin (p<0.04, creatine (p<0.03 and creatine phosphokinase (p<0.01 were higher in mountaineers. Other hematological and biochemical parameters, i.e., erythrocytes, leukocytes, hemoglobin and hematocrit, did not change significantly. Conclusion: Our results show that regular exposure to high altitude increased the serum levels of some acute phase proteins with anti-inflammatory properties.

  13. United States high-altitude test experiences. A review emphasizing the impact on the environment

    International Nuclear Information System (INIS)

    Hoerlin, H.

    1976-06-01

    The US high-altitude nuclear explosions of the 1955-1962 period are listed chronologically; dates, locations, and yields are given. The major physical phases of the interactions of the weapon outputs with the atmosphere are described, such as the formation of fireballs at the low high-altitudes and the partition of energies and their distribution over very large spaces at the higher high-altitudes. The effects of these explosions on the normal activities of populations and the protective measures taken are documented. Many scientific observations, together with their significance and values, are reviewed. 109 refs

  14. Science 101: Why Does It Take Longer to Boil Potatoes at High Altitudes?

    Science.gov (United States)

    Robertson, Bill

    2017-01-01

    Why Does It Take Longer to Boil Potatoes at High Altitudes? This column provides background science information for elementary teachers. This month's issue looks at why water boils at different temperatures at different altitudes.

  15. Identification of Color Development Potential of Quartz by Raman Spectroscopy

    International Nuclear Information System (INIS)

    Gomides Alkmim, D.; Soares Lameiras, F.

    2013-01-01

    Colorless quartz is usually exposed to ionizing radiation (gamma rays or high energy electron beams) in order to acquire different colors for jewelry. This is due to the presence of traces of some elements such as aluminum, iron, hydrogen, lithium, or sodium, which are responsible for the extrinsic colors developed after irradiation. Most quartz crystals are extracted colorless from nature and it is necessary to separate those that can develop colors from those that cannot. This can be done through irradiation tests, which take a long time. Other option is to collect the infrared signature of colorless quartz. However, infrared spectroscopic analysis is quite expensive, especially when using portable devices. Raman spectroscopy is now available as an inexpensive and portable technique that could provide identification of the samples of colorless quartz still in the field, facilitating the prediction for their economic exploitation. In addition, Raman spectroscopy usually requires a minimum or no sample preparation. This paper presents an investigation of the feasibility of using Raman spectroscopy as a substitute for infrared spectroscopy to predict the potential for color development of quartz. A band at 3595 cm -1 was observed, only along the c axis of a prasiolite excited by a high power 514 nm laser. This band was nor observed in quartz samples that do not develop color after irradiation, hence requiring further studies. (Author)

  16. Syndrome of Acute Anxiety Among Marines After Recent Arrival at High Altitude

    Science.gov (United States)

    2014-05-01

    Naval Health Research Center Syndrome of Acute Anxiety Among Marines After Recent Arrival at High Altitude Michael K. Sracic Darren Thomas...Allen Pate Jacob Norris Marc Norman, Jeffrey H. Gertsch Report No. 13-29 The views expressed in this article are those of the authors...MEDICINE, 179, 5:559, 2014 Syndrome of Acute Anxiety Among Marines After Recent Arrival at High Altitude LT Michael K. Sracic, MC USN*; LT Darren Thomas

  17. Multi-terminal Two-color ZnCdSe/ZnCdMgSe Based Quantum-well Infrared Photodetector

    Science.gov (United States)

    Kaya, Yasin; Ravikumar, Arvind; Chen, Guopeng; Tamargo, Maria C.; Shen, Aidong; Gmachl, Claire

    Target recognition and identification applications benefits from two-color infrared (IR) detectors in the mid and long-wavelength IR regions. Currently, InGaAs/AlGaAs and GaAs/AlGaAs multiple quantum wells (QWs) grown on GaAs substrate are the most commonly used two-color QW IR photodetectors (QWIPs). However, the lattice-mismatch and the buildup of strain limit the number of QWs that can be grown, in turn increasing the dark current noise, and limiting the device detectivity.In this work, we report on two-color QWIPs based on the large conduction band offset (~1.12ev) ZnCdSe/ZnCdMgSe material system lattice matched to InP. QWIPs were designed based on a bound to quasi-bound transition, centered at 4 μm and 7 μm and each QW is repeated 50 times to eliminate the high dark current and a contact layer is inserted between the two stacks of QWs for independent electrical contacts. Wafers are processed into two step rectangular mesas by lithography and wet etching. Experiments showed absorption spectra centered at 4.9 μm and 7.6 μm at 80 K and the full width at half maximums were Δλ / λ = 21 % and Δλ / λ = 23 % , respectively. Current work studies the Johnson and the background noise limited detectivities of these QWIPs. Current address: School of Earth, Energy and Environmental Sciences, Stanford, CA 94305, USA.

  18. Energy management strategy for solar-powered high-altitude long-endurance aircraft

    International Nuclear Information System (INIS)

    Gao, Xian-Zhong; Hou, Zhong-Xi; Guo, Zheng; Liu, Jian-Xia; Chen, Xiao-Qian

    2013-01-01

    Highlights: ► A new Energy Management Strategy (EMS) for high-altitude solar-powered aircraft is purposed. ► The simulations show that the aircraft can always keep the altitude above 16 km with the proposed EMS. ► The proposed EMS is capable to alleviate the power consumed for aircraft during night. ► The main technologies to improve the flight performance of aircraft are analyzed. - Abstract: Development of solar-powered High-Altitude Long-Endurance (HALE) aircraft has a great impact on both military and civil aviation industries since its features in high-altitude and energy source can be considered inexhaustible. Owing to the development constraints of rechargeable batteries, the solar-powered HALE aircraft must take amount of rechargeable batteries to fulfill the energy requirement in night, which greatly limits the operation altitude of aircraft. In order to solve this problem, a new Energy Management Strategy (EMS) is proposed based on the idea that the solar energy can be partly stored in gravitational potential in daytime. The flight path of HALE aircraft is divided into three stages. During the stage 1, the solar energy is stored in both lithium–sulfur battery and gravitational potential. The gravitational potential is released in stage 2 by gravitational gliding and the required power in stage 3 is supplied by lithium–sulfur battery. Correspondingly, the EMS is designed for each stage. The simulation results show that the aircraft can always keep the altitude above 16 km with the proposed EMS, and the power consumed during night can be also alleviated. Comparing with the current EMS, about 23.5% energy is remained in batteries with the proposed EMS during one day–night cycle. The sensitivities of the improvement of crucial technologies to the performance of aircraft are also analyzed. The results show that the enhancement of control and structural system, lithium–sulfur battery, and solar cell are ranked in descending order for the

  19. Peripheral blood lymphocytes: a model for monitoring physiological adaptation to high altitude.

    Science.gov (United States)

    Mariggiò, Maria A; Falone, Stefano; Morabito, Caterina; Guarnieri, Simone; Mirabilio, Alessandro; Pilla, Raffaele; Bucciarelli, Tonino; Verratti, Vittore; Amicarelli, Fernanda

    2010-01-01

    Depending on the absolute altitude and the duration of exposure, a high altitude environment induces various cellular effects that are strictly related to changes in oxidative balance. In this study, we used in vitro isolated peripheral blood lymphocytes as biosensors to test the effect of hypobaric hypoxia on seven climbers by measuring the functional activity of these cells. Our data revealed that a 21-day exposure to high altitude (5000 m) (1) increased intracellular Ca(2+) concentration, (2) caused a significant decrease in mitochondrial membrane potential, and (3) despite possible transient increases in intracellular levels of reactive oxygen species, did not significantly change the antioxidant and/or oxidative damage-related status in lymphocytes and serum, assessed by measuring Trolox-equivalent antioxidant capacity, glutathione peroxidase activity, vitamin levels, and oxidatively modified proteins and lipids. Overall, these results suggest that high altitude might cause an impairment in adaptive antioxidant responses. This, in turn, could increase the risk of oxidative-stress-induced cellular damage. In addition, this study corroborates the use of peripheral blood lymphocytes as an easily handled model for monitoring adaptive response to environmental challenge.

  20. The Laddermill : Innovative Wind Energy from High Altitudes in Holland and Australia

    NARCIS (Netherlands)

    Lansdorp, B.; Williams, P.

    2006-01-01

    The Laddermill is a novel concept to harvest electricity from high altitude winds. The concept's operating principle is to drive an electric generator using tethered kites. Several kites are deployed to altitudes of more than 1 km by means of a single cable that is connected to a drum on the

  1. The structure of high altitude O+ energization and outflow: a case study

    Directory of Open Access Journals (Sweden)

    H. Nilsson

    2004-07-01

    Full Text Available Multi-spacecraft observations from the CIS ion spectrometers on board the Cluster spacecraft have been used to study the structure of high-altitude oxygen ion energization and outflow. A case study taken from 12 April 2004 is discussed in more detail. In this case the spacecraft crossed the polar cap, mantle and high-altitude cusp region at altitudes between 4RE and 8RE and 2 of the spacecraft provided data. The oxygen ions were seen as a beam with narrow energy distribution, and increasing field-aligned velocity and temperature at higher altitude further in the upstream flow direction. The peak O+ energy was typically just above the highest energy of observed protons. The observed energies reached the upper limit of the CIS ion spectrometer, i.e. 38keV. Moment data from the spacecraft have been cross-correlated to determine cross-correlation coefficients, as well as the phase delay between the spacecraft. Structures in ion density, temperature and field-aligned flow appear to drift with the observed field-perpendicular drift. This, together with a velocity dispersion analysis, indicates that much of the structure can be explained by transverse heating well below the spacecraft. However, temperature isotropy and the particle flux as a function of field-aligned velocity are inconsistent with a single altitude Maxwellian source. Heating over extended altitude intervals, possibly all the way up to the observation point, seem consistent with the observations.

  2. A DECADE OF MAPPING SUBMERGED AQUATIC VEGETATION USING COLOR INFRARED AERIAL PHOTOGRAPHY: METHODS USED AND LESSONS LEARNED - 5-14-2014

    Science.gov (United States)

    Annual color infrared (CIR) aerial photographs acquired annually between 1997 and 2007 were used to classify distributions of intertidal and shallow subtidal native eelgrass Zostera marina and non-indigenous dwarf eelgrass Z. japonica in lower Yaquina estuary, Oregon. The use of...

  3. Dose-response of altitude training: how much altitude is enough?

    Science.gov (United States)

    Levine, Benjamin D; Stray-Gundersen, James

    2006-01-01

    Altitude training continues to be a key adjunctive aid for the training of competitive athletes throughout the world. Over the past decade, evidence has accumulated from many groups of investigators that the "living high--training low" approach to altitude training provides the most robust and reliable performance enhancements. The success of this strategy depends on two key features: 1) living high enough, for enough hours per day, for a long enough period of time, to initiate and sustain an erythropoietic effect of high altitude; and 2) training low enough to allow maximal quality of high intensity workouts, requiring high rates of sustained oxidative flux. Because of the relatively limited access to environments where such a strategy can be practically applied, numerous devices have been developed to "bring the mountain to the athlete," which has raised the key issue of the appropriate "dose" of altitude required to stimulate an acclimatization response and performance enhancement. These include devices using molecular sieve technology to provide a normobaric hypoxic living or sleeping environment, approaches using very high altitudes (5,500m) for shorter periods of time during the day, and "intermittent hypoxic training" involving breathing very hypoxic gas mixtures for alternating 5 minutes periods over the course of 60-90 minutes. Unfortunately, objective testing of the strategies employing short term (less than 4 hours) normobaric or hypobaric hypoxia has failed to demonstrate an advantage of these techniques. Moreover individual variability of the response to even the best of living high--training low strategies has been great, and the mechanisms behind this variability remain obscure. Future research efforts will need to focus on defining the optimal dosing strategy for these devices, and determining the underlying mechanisms of the individual variability so as to enable the individualized "prescription" of altitude exposure to optimize the performance of

  4. No Change in Running Mechanics With Live High-Train Low Altitude Training in Elite Distance Runners.

    Science.gov (United States)

    Stickford, Abigail S L; Wilhite, Daniel P; Chapman, Robert F

    2017-01-01

    Investigations into ventilatory, metabolic, and hematological changes with altitude training have been completed; however, there is a lack of research exploring potential gait-kinematic changes after altitude training, despite a common complaint of athletes being a lack of leg "turnover" on return from altitude training. To determine if select kinematic variables changed in a group of elite distance runners after 4 wk of altitude training. Six elite male distance runners completed a 28-d altitude-training intervention in Flagstaff, AZ (2150 m), following a modified "live high-train low" model, wherein higherintensity runs were performed at lower altitudes (945-1150 m) and low-intensity sessions were completed at higher altitudes (1950-2850 m). Gait parameters were measured 2-9 d before departure to altitude and 1 to 2 d after returning to sea level at running speeds of 300-360 m/min. No differences were found in ground-contact time, swing time, or stride length or frequency after altitude training (P > .05). Running mechanics are not affected by chronic altitude training in elite distance runners. The data suggest that either chronic training at altitude truly has no effect on running mechanics or completing the live high-train low model of altitude training, where higher-velocity workouts are completed at lower elevations, mitigates any negative mechanical adaptations that may be associated with chronic training at slower speeds.

  5. SDSS QUASARS IN THE WISE PRELIMINARY DATA RELEASE AND QUASAR CANDIDATE SELECTION WITH OPTICAL/INFRARED COLORS

    International Nuclear Information System (INIS)

    Wu Xuebing; Hao Guoqiang; Jia Zhendong; Zhang Yanxia; Peng Nanbo

    2012-01-01

    We present a catalog of 37,842 quasars in the Sloan Digital Sky Survey (SDSS) Data Release 7, which have counterparts within 6'' in the Wide-field Infrared Survey Explorer (WISE) Preliminary Data Release. The overall WISE detection rate of the SDSS quasars is 86.7%, and it decreases to less than 50.0% when the quasar magnitude is fainter than i = 20.5. We derive the median color-redshift relations based on this SDSS-WISE quasar sample and apply them to estimate the photometric redshifts of the SDSS-WISE quasars. We find that by adding the WISE W1- and W2-band data to the SDSS photometry we can increase the photometric redshift reliability, defined as the percentage of sources with photometric and spectroscopic redshift difference less than 0.2, from 70.3% to 77.2%. We also obtain the samples of WISE-detected normal and late-type stars with SDSS spectroscopy, and present a criterion in the z – W1 versus g – z color-color diagram, z – W1 > 0.66(g – z) + 2.01, to separate quasars from stars. With this criterion we can recover 98.6% of 3089 radio-detected SDSS-WISE quasars with redshifts less than four and overcome the difficulty in selecting quasars with redshifts between 2.2 and 3 from SDSS photometric data alone. We also suggest another criterion involving the WISE color only, W1 – W2 > 0.57, to efficiently separate quasars with redshifts less than 3.2 from stars. In addition, we compile a catalog of 5614 SDSS quasars detected by both WISE and UKIDSS surveys and present their color-redshift relations in the optical and infrared bands. By using the SDSS ugriz, UKIDSS, YJHK, and WISE W1- and W2-band photometric data, we can efficiently select quasar candidates and increase the photometric redshift reliability up to 87.0%. We discuss the implications of our results on the future quasar surveys. An updated SDSS-WISE quasar catalog consisting of 101,853 quasars with the recently released WISE all-sky data is also provided.

  6. Influence of infrared final cooking on color, texture and cooking characteristics of ohmically pre-cooked meatball.

    Science.gov (United States)

    Yildiz Turp, Gulen; Icier, Filiz; Kor, Gamze

    2016-04-01

    The objective of the current study was to improve the quality characteristics of ohmically pre-cooked beef meatballs via infrared cooking as a final stage. Samples were pre-cooked in a specially designed-continuous type ohmic cooker at a voltage gradient of 15.26 V/cm for 92 s. Infrared cooking was then applied to the pre-cooked samples at different combinations of heat fluxes (3.706, 5.678, and 8.475 kW/m(2)), application distances (10.5, 13.5, and 16.5 cm) and application durations (4, 8, and 12min). Effects of these parameters on color, texture and cooking characteristics of ohmically pre-cooked beef meatballs were investigated. The appearance of ohmically pre-cooked meatball samples was improved via infrared heating. A dark brown layer desired in cooked meatballs formed on the surface of the meatballs with lowest application distance (10.5 cm) and longest application duration (12 min). The texture of the samples was also improved with these parameters. However the cooking yield of the samples decreased at the longest application duration of infrared heating. Copyright © 2015 Elsevier Ltd. All rights reserved.

  7. Ultraviolet and infrared emission from lightning discharges observed at Aragats

    International Nuclear Information System (INIS)

    Chilingarian, A.; Karapetyan, T.; Pokhsraryan, D.; Bogomolov, V.; Garipov, G.; Panasyuk, M.; Svertilov, S.; Saleev, K.

    2016-01-01

    The ultraviolet and infrared optical sensors previously used at RELEC space missions were installed at the high altitude research station Aragats at 3200 m above the sea level. The spectral composition and temporal structure of the recorded optical signals and measurements of the electrostatic field and atmospheric discharges obtained by “fast” and “slow” field sensors have been compared. Measurements of lightning and related to them phenomena observed at the mountain altitude and on board of orbiting satellites are compared. (author)

  8. Analysis of the Hybrid Power System for High-Altitude Unmanned Aircraft

    Directory of Open Access Journals (Sweden)

    Kangwen Sun

    2015-01-01

    Full Text Available The application of single solar array on high-altitude unmanned aircraft will waste energy because of its low conversion efficiency. Furthermore, since its energy utilization is limited, the surface temperature of solar array will rise to 70°C due to the waste solar energy, thus reducing the electrical performance of the solar array. In order to reuse the energy converted into heat by solar array, a hybrid power system is presented in this paper. In the hybrid power system, a new electricity-generating method is adopted to spread the photovoltaic cell on the wing surface and arrange photothermal power in the wing box section. Because the temperature on the back of photovoltaic cell is high, it can be used as the high-temperature heat source. The lower wing surface can be a low-temperature cold source. A high-altitude unmanned aircraft was used to analyze the performances of pure solar-powered aircraft and hybrid powered aircraft. The analysis result showed that the hybrid system could reduce the area of wing by 19% and that high-altitude unmanned aircraft with a 35 m or less wingspan could raise the utilization rate of solar energy per unit area after adopting the hybrid power system.

  9. Genomic analysis of natural selection and phenotypic variation in high-altitude mongolians.

    Directory of Open Access Journals (Sweden)

    Jinchuan Xing

    Full Text Available Deedu (DU Mongolians, who migrated from the Mongolian steppes to the Qinghai-Tibetan Plateau approximately 500 years ago, are challenged by environmental conditions similar to native Tibetan highlanders. Identification of adaptive genetic factors in this population could provide insight into coordinated physiological responses to this environment. Here we examine genomic and phenotypic variation in this unique population and present the first complete analysis of a Mongolian whole-genome sequence. High-density SNP array data demonstrate that DU Mongolians share genetic ancestry with other Mongolian as well as Tibetan populations, specifically in genomic regions related with adaptation to high altitude. Several selection candidate genes identified in DU Mongolians are shared with other Asian groups (e.g., EDAR, neighboring Tibetan populations (including high-altitude candidates EPAS1, PKLR, and CYP2E1, as well as genes previously hypothesized to be associated with metabolic adaptation (e.g., PPARG. Hemoglobin concentration, a trait associated with high-altitude adaptation in Tibetans, is at an intermediate level in DU Mongolians compared to Tibetans and Han Chinese at comparable altitude. Whole-genome sequence from a DU Mongolian (Tianjiao1 shows that about 2% of the genomic variants, including more than 300 protein-coding changes, are specific to this individual. Our analyses of DU Mongolians and the first Mongolian genome provide valuable insight into genetic adaptation to extreme environments.

  10. Prevalence of high altitude pulmonary hypertension among the natives of Spiti Valley--a high altitude region in Himachal Pradesh, India.

    Science.gov (United States)

    Negi, Prakash Chand; Marwaha, Rajeev; Asotra, Sanjeev; Kandoria, Arvind; Ganju, Neeraj; Sharma, Rajesh; Kumar, Ravi V; Bhardwaj, Rajeev

    2014-12-01

    The study aimed to determine the prevalence of high altitude pulmonary hypertension (HAPH) and its predisposing factors among natives of Spiti Valley. A cross-sectional survey study was done on the permanent natives of Spiti Valley residing at an altitude of 3000 m to 4200 m. Demographic characteristics, health behavior, anthropometrics, and blood pressure were recorded. Investigations included recording of 12 lead electrocardiogram (ECG), SaO2 with pulse oximeter, spirometry and echocardiography study, and measurement of Hb levels using the cynmethhemoglobin method. HAPH was diagnosed using criteria; tricuspid regurgitation (TR) gradient of ≥46 mmHg. ECG evidence of RV overload on 12 lead ECG was documented based on presence of 2 out of 3 criteria; R>S in V1, right axis deviation or RV strain, T wave inversion in V1 and V2. Data of 1087 subjects were analyzed who were free of cardiorespiratory diseases to determine the prevalence of HAPH and its predisposing factors. HAPH was recorded in 3.23% (95% C.I. of 0.9-8.1%) and ECG evidence of right ventricular (RV) overload was 1.5% in the study population. Prevalence of HAPH was not different in men and women 2.63% vs. 3.54% p<0.2. Age (Z statistics of 3.4 p<0.0006), hypoxemia (Z statistics of 2.9 p<0.002), and erythrocythemia (Z statistics of 4.7 p<0.003) were independently associated with HAPH. Altitude of residence was not found to be significantly associated with HAPH, although there was a trend of increasing prevalence with increasing altitude. It can be concluded that HAPH is prevalent in 3.23% of natives of Spiti Valley. Increasing age, erythrocythemia and hypoxemia are independent predisposing factors.

  11. Tests of the Daimler D-IVa Engine at a High Altitude Test Bench

    Science.gov (United States)

    Noack, W G

    1920-01-01

    Reports of tests of a Daimler IVa engine at the test-bench at Friedrichshafen, show that the decrease of power of that engine, at high altitudes, was established, and that the manner of its working when air is supplied at a certain pressure was explained. These tests were preparatory to the installation of compressors in giant aircraft for the purpose of maintaining constant power at high altitudes.

  12. Asthma in Patients Climbing to High and Extreme Altitudes in the Tibetan Everest Region

    NARCIS (Netherlands)

    Huismans, Henrike K.; Douma, W. Rob; Kerstjens, Huib A. M.; Renkema, Tineke E. J.

    Objectives: The aim of this study was to investigate the behavior of asthma in patients traveling to high and extreme altitudes. Methods: Twenty-four Dutch patients with mild asthma did a trekking at high and extreme altitudes (up to 6410 m = 21030 ft) in the Tibetan Everest region. Asthma symptoms,

  13. A quantitative analysis of TIMS data obtained on the Learjet 23 at various altitudes

    Science.gov (United States)

    Jaggi, S.

    1992-01-01

    A series of Thermal Infrared Multispectral Scanner (TIMS) data acquisition flights were conducted on the NASA Learjet 23 at different altitudes over a test site. The objective was to monitor the performance of the TIMS (its estimation of the brightness temperatures of the ground scene) with increasing altitude. The results do not show any significant correlation between the brightness temperatures and the altitude. The analysis indicates that the estimation of the temperatures is a function of the accuracy of the atmospheric correction used for each altitude.

  14. Estimation of walrus populations on sea ice with infrared imagery and aerial photography

    Science.gov (United States)

    Udevitz, M.S.; Burn, D.M.; Webber, M.A.

    2008-01-01

    Population sizes of ice-associated pinnipeds have often been estimated with visual or photographic aerial surveys, but these methods require relatively slow speeds and low altitudes, limiting the area they can cover. Recent developments in infrared imagery and its integration with digital photography could allow substantially larger areas to be surveyed and more accurate enumeration of individuals, thereby solving major problems with previous survey methods. We conducted a trial survey in April 2003 to estimate the number of Pacific walruses (Odobenus rosmarus divergens) hauled out on sea ice around St. Lawrence Island, Alaska. The survey used high altitude infrared imagery to detect groups of walruses on strip transects. Low altitude digital photography was used to determine the number of walruses in a sample of detected groups and calibrate the infrared imagery for estimating the total number of walruses. We propose a survey design incorporating this approach with satellite radio telemetry to estimate the proportion of the population in the water and additional low-level flights to estimate the proportion of the hauled-out population in groups too small to be detected in the infrared imagery. We believe that this approach offers the potential for obtaining reliable population estimates for walruses and other ice-associated pinnipeds. ?? 2007 by the Society for Marine Mammalogy.

  15. A method for sampling microbial aerosols using high altitude balloons.

    Science.gov (United States)

    Bryan, N C; Stewart, M; Granger, D; Guzik, T G; Christner, B C

    2014-12-01

    Owing to the challenges posed to microbial aerosol sampling at high altitudes, very little is known about the abundance, diversity, and extent of microbial taxa in the Earth-atmosphere system. To directly address this knowledge gap, we designed, constructed, and tested a system that passively samples aerosols during ascent through the atmosphere while tethered to a helium-filled latex sounding balloon. The sampling payload is ~ 2.7 kg and comprised of an electronics box and three sampling chambers (one serving as a procedural control). Each chamber is sealed with retractable doors that can be commanded to open and close at designated altitudes. The payload is deployed together with radio beacons that transmit GPS coordinates (latitude, longitude and altitude) in real time for tracking and recovery. A cut mechanism separates the payload string from the balloon at any desired altitude, returning all equipment safely to the ground on a parachute. When the chambers are opened, aerosol sampling is performed using the Rotorod® collection method (40 rods per chamber), with each rod passing through 0.035 m3 per km of altitude sampled. Based on quality control measurements, the collection of ~ 100 cells rod(-1) provided a 3-sigma confidence level of detection. The payload system described can be mated with any type of balloon platform and provides a tool for characterizing the vertical distribution of microorganisms in the troposphere and stratosphere. Copyright © 2014 Elsevier B.V. All rights reserved.

  16. Surface Temperature Mapping of the University of Northern Iowa Campus Using High Resolution Thermal Infrared Aerial Imageries

    Directory of Open Access Journals (Sweden)

    Ramanathan Sugumaran

    2008-08-01

    Full Text Available The goal of this project was to map the surface temperature of the University of Northern Iowa campus using high-resolution thermal infrared aerial imageries. A thermal camera with a spectral bandwidth of 3.0-5.0 μm was flown at the average altitude of 600 m, achieving ground resolution of 29 cm. Ground control data was used to construct the pixelto-temperature conversion model, which was later used to produce temperature maps of the entire campus and also for validation of the model. The temperature map then was used to assess the building rooftop conditions and steam line faults in the study area. Assessment of the temperature map revealed a number of building structures that may be subject to insulation improvement due to their high surface temperatures leaks. Several hot spots were also identified on the campus for steam pipelines faults. High-resolution thermal infrared imagery proved highly effective tool for precise heat anomaly detection on the campus, and it can be used by university facility services for effective future maintenance of buildings and grounds.

  17. Surface Temperature Mapping of the University of Northern Iowa Campus Using High Resolution Thermal Infrared Aerial Imageries

    Science.gov (United States)

    Savelyev, Alexander; Sugumaran, Ramanathan

    2008-01-01

    The goal of this project was to map the surface temperature of the University of Northern Iowa campus using high-resolution thermal infrared aerial imageries. A thermal camera with a spectral bandwidth of 3.0-5.0 μm was flown at the average altitude of 600 m, achieving ground resolution of 29 cm. Ground control data was used to construct the pixel- to-temperature conversion model, which was later used to produce temperature maps of the entire campus and also for validation of the model. The temperature map then was used to assess the building rooftop conditions and steam line faults in the study area. Assessment of the temperature map revealed a number of building structures that may be subject to insulation improvement due to their high surface temperatures leaks. Several hot spots were also identified on the campus for steam pipelines faults. High-resolution thermal infrared imagery proved highly effective tool for precise heat anomaly detection on the campus, and it can be used by university facility services for effective future maintenance of buildings and grounds. PMID:27873800

  18. Signatures of electric fields from high and low altitude particle distributions

    International Nuclear Information System (INIS)

    Mizera, P.F.; Fennell, J.F.

    1977-01-01

    Measurements of high altitude (<1.3 R/sub e/) ions and electrons at auroral energies are used to provide evidence of parallel electric field acceleration over the dusk to midnight auroral regions for both the north and south hemispheres. The data, taken on August 12, 1976 by charged particle spectrometers on the S3-3 satellite, show evidence of potential differences of approx.2 kV below and approx.1 kV above a satellite altitude of 7300 km

  19. Certification and safety aspects relating to the transport of passengers on high altitude balloons in Europe

    Science.gov (United States)

    Schoenmaker, Annelie

    2014-07-01

    High-altitude balloons typically fly between 25 and 50 km in altitude, which, while below the Karman line of 100 km, is yet far above the altitudes typically flown by aircraft. For example, the highest-flying commercial aircraft - the Concorde - had a maximum cruising altitude of only 18 km. zero2infinity, a Spanish company, is currently developing a pressurized pod named “bloon” which will be capable of lifting six people, including two pilot crew members and four paying passengers, to an altitude of 36 km through the use of high-altitude balloons. The boundary between Airspace and Outer Space has never been legally defined, mostly because of the lack of activities taking place between the altitude where airplanes fly and the lowest orbiting spacecraft. High-altitude balloons do fly at these in-between altitudes and the prospect of commercializing access to these parts of the stratosphere poses some questions in a new light. Given the relatively low altitude at which they fly, it may well be that these types of balloons would be considered to operate exclusively within air space. However, given the technology involved in crewed high altitude balloon flights, which is more similar to spacecraft engineering than to traditional hot-air or gas ballooning, it is necessary to evaluate the various legal regimes, codes, and regulations that would apply to such flights, especially regarding licenses and liabilities. For high altitude balloon flights commencing in Europe, the European Aviation Safety Agency (EASA) would very likely be the competent certification or licensing agency for these flights, although there would likely be input from various national aviation authorities as well. However, because the European Commission (EC) has not yet issued regulations regarding commercial spaceflight, particularly the use of high altitude balloons, new rules and regulations governing such flights may still need to be drafted and promulgated. With the development of

  20. S-40: Acute Phase Protein Increse in High Altitude Mountaineers

    Directory of Open Access Journals (Sweden)

    Tolga Saka

    2017-03-01

    Full Text Available “Erciyes Tigers” are an elite group of high altitude climbers. They have been climbing ErciyesMountain (3500 m, in Kayseri, Turkey once a week at least for ten years. When they climb Erciyes in winter, they also take a snow bath. This study investigated the effects of regular high altitude climbing on the metabolic and hematological responses of mountaineers. Venous blood samples were taken to investigate hematological, biochemical parameters and some hormone values from 21 mountaineers and 16 healthy age-matched sedentary volunteers at resting condition. The neutrophil/lymphocyte (N/L ratio was calculated. The N/L was associated with an increased risk of long-term mortality and it could provide a good measure of exercise stress and subsequent recovery. Most of the hematological and biochemical parameters i.e., erythrocyte, leukocyte, hemoglobin and hematocrit values did not change significantly. The neutrophil to lymphocyte (N/L ratio was significantly (p<0.04 decreased in the mountaineer compared with the sedentary group. Total protein (p<0.000 and albumin (0.001 were lower, while ferritin (p<0.04, creatine (p<0.03 and creatine phosphokinase levels (p<0.01 were higher in mountaineers. Our results show that regular high altitude climbing increased serum levels of some acute-phase proteins and these increments were not transient.

  1. Prediction of pH and color in pork meat using VIS-NIR Near-infrared Spectroscopy (NIRS

    Directory of Open Access Journals (Sweden)

    Elton Jhones Granemann FURTADO

    2018-06-01

    Full Text Available Abstract The potential of near-infrared spectroscopy (NIRS to predict the physicochemical characteristics of the porcine longissimus dorsi (LD muscle was evaluated in comparison to the standard methods of pH and color for meat quality analysis compared to the pH results with Colorimeter and pH meter. Spectral information from each sample (n = 77 was obtained as the average of 32 successive scans acquired over a spectral range from 400 - 2498 nm with a 2 - nm gap for calibration and validation models. Partial least squares (PLS regression was used for each individual model. An R2 and a residual predictive deviation (RPD of 0.67/1.7, 0.86/2, and 0.76/1.9 were estimated for color parameters L*, a *, and b*, respectively. Final pH had an R2 of 0.67 and a RPD of 1.6. NIRS showed great potential to predict color parameter a * of porcine LD muscle. Further studies with larger samples should help improve model quality.

  2. Coherent control of D2/H2 dissociative ionization by a mid-infrared two-color laser field

    International Nuclear Information System (INIS)

    Wanie, Vincent; Ibrahim, Heide; Beaulieu, Samuel; Thiré, Nicolas; Schmidt, Bruno E; Légaré, François; Deng, Yunpei; Alnaser, Ali S; Litvinyuk, Igor V; Tong, Xiao-Min

    2016-01-01

    Steering the electrons during an ultrafast photo-induced process in a molecule influences the chemical behavior of the system, opening the door to the control of photochemical reactions and photobiological processes. Electrons can be efficiently localized using a strong laser field with a well-designed temporal shape of the electric component. Consequently, many experiments have been performed with laser sources in the near-infrared region (800 nm) in the interest of studying and enhancing the electron localization. However, due to its limited accessibility, the mid-infrared (MIR) range has barely been investigated, although it allows to efficiently control small molecules and even more complex systems. To push further the manipulation of basic chemical mechanisms, we used a MIR two-color (1800 and 900 nm) laser field to ionize H 2 and D 2 molecules and to steer the remaining electron during the photo-induced dissociation. The study of this prototype reaction led to the simultaneous control of four fragmentation channels. The results are well reproduced by a theoretical model solving the time-dependent Schrödinger equation for the molecular ion, identifying the involved dissociation mechanisms. By varying the relative phase between the two colors, asymmetries (i.e., electron localization selectivity) of up to 65% were obtained, corresponding to enhanced or equivalent levels of control compared to previous experiments. Experimentally easier to implement, the use of a two-color laser field leads to a better electron localization than carrier-envelope phase stabilized pulses and applying the technique in the MIR range reveals more dissociation channels than at 800 nm. (paper)

  3. Water level changes of high altitude lakes in Himalaya–Karakoram ...

    Indian Academy of Sciences (India)

    2Department of Geology, University of Pune, Pune 411 007, India. 3Chhattisgarh Council of .... influenced by three climate patterns as categorized by precipitation regime: (1) ... Water level changes of high altitude lakes in Himalaya–Karakoram. 1535 ...... mate warming and growth of high elevation inland lakes on the ...

  4. Defining the "dose" of altitude training: how high to live for optimal sea level performance enhancement.

    Science.gov (United States)

    Chapman, Robert F; Karlsen, Trine; Resaland, Geir K; Ge, R-L; Harber, Matthew P; Witkowski, Sarah; Stray-Gundersen, James; Levine, Benjamin D

    2014-03-15

    Chronic living at altitudes of ∼2,500 m causes consistent hematological acclimatization in most, but not all, groups of athletes; however, responses of erythropoietin (EPO) and red cell mass to a given altitude show substantial individual variability. We hypothesized that athletes living at higher altitudes would experience greater improvements in sea level performance, secondary to greater hematological acclimatization, compared with athletes living at lower altitudes. After 4 wk of group sea level training and testing, 48 collegiate distance runners (32 men, 16 women) were randomly assigned to one of four living altitudes (1,780, 2,085, 2,454, or 2,800 m). All athletes trained together daily at a common altitude from 1,250-3,000 m following a modified live high-train low model. Subjects completed hematological, metabolic, and performance measures at sea level, before and after altitude training; EPO was assessed at various time points while at altitude. On return from altitude, 3,000-m time trial performance was significantly improved in groups living at the middle two altitudes (2,085 and 2,454 m), but not in groups living at 1,780 and 2,800 m. EPO was significantly higher in all groups at 24 and 48 h, but returned to sea level baseline after 72 h in the 1,780-m group. Erythrocyte volume was significantly higher within all groups after return from altitude and was not different between groups. These data suggest that, when completing a 4-wk altitude camp following the live high-train low model, there is a target altitude between 2,000 and 2,500 m that produces an optimal acclimatization response for sea level performance.

  5. Food Abundance Is the Main Determinant of High-Altitude Range Use in Snub-Nosed Monkeys

    Directory of Open Access Journals (Sweden)

    Cyril C. Grueter

    2012-01-01

    Full Text Available High-altitude dwelling primates have to optimize navigating a space that contains both a vertical and horizontal component. Black-and-white or Yunnan snub-nosed monkeys (Rhinopithecus bieti are extreme by primate standards in inhabiting relatively cold subalpine temperate forests at very high altitudes where large seasonal variation in climate and food availability is expected to profoundly modulate their ranging strategies so as to ensure a positive energy balance. A “semi-nomadic” group of R. bieti was followed for 20 months in the montane Samage Forest, Baimaxueshan Nature Reserve, Yunnan, PRC, which consisted of evergreen conifers, oaks, and deciduous broadleaf trees. The aim of this study was to disentangle the effects of climate and phenology on patterns of altitudinal range use. Altitude used by the group ranged from a maximum of 3550 m in July 2007 to a minimum of 3060 m in April 2006. The proportional use of lichen, the monkeys’ staple fallback food, in the diet explained more variation in monthly use of altitudes than climatic factors and availability of flush and fruit. The abundance of lichens at high altitudes, the lack of alternative foods in winter, and the need to satisfy the monkey's basal energetic requirements explain the effect of lichenivory on use of altitudes.

  6. The lactate paradox revisited in lowlanders during acclimatization to 4100 m and in high-altitude natives

    DEFF Research Database (Denmark)

    Van Hall, Gerrit; Lundby, C; Araoz, M

    2009-01-01

    Chronic hypoxia has been proposed to induce a closer coupling in human skeletal muscle between ATP utilization and production in both lowlanders (LN) acclimatizing to high altitude and high-altitude natives (HAN), linked with an improved match between pyruvate availability and its use...... and remained at this higher level during the acclimatization period. HAN had similar high values; however, at the moment of exhaustion their muscle lactate, ADP and IMP content and Cr/PCr ratio were higher than in LN. In conclusion, sea-level residents in the course of acclimatization to high altitude did...... not exhibit a reduced capacity for the active muscle to produce lactate. Thus, the lactate paradox concept could not be demonstrated. High-altitude natives from the Andes actually exhibit a higher anaerobic energy production than lowlanders after 8 weeks of acclimatization reflected by an increased muscle...

  7. Visible Color and Photometry of Bright Materials on Vesta

    Science.gov (United States)

    Schroder, S. E.; Li, J. Y.; Mittlefehldt, D. W.; Pieters, C. M.; De Sanctis, M. C.; Hiesinger, H.; Blewett, D. T.; Russell, C. T.; Raymond, C. A.; Keller, H. U.

    2012-01-01

    The Dawn Framing Camera (FC) collected images of the surface of Vesta at a pixel scale of 70 m in the High Altitude Mapping Orbit (HAMO) phase through its clear and seven color filters spanning from 430 nm to 980 nm. The surface of Vesta displays a large diversity in its brightness and colors, evidently related to the diverse geology [1] and mineralogy [2]. Here we report a detailed investigation of the visible colors and photometric properties of the apparently bright materials on Vesta in order to study their origin. The global distribution and the spectroscopy of bright materials are discussed in companion papers [3, 4], and the synthesis results about the origin of Vestan bright materials are reported in [5].

  8. Statistics of high-altitude and high-latitude O+ ion outflows observed by Cluster/CIS

    Directory of Open Access Journals (Sweden)

    A. Korth

    2005-07-01

    Full Text Available The persistent outflows of O+ ions observed by the Cluster CIS/CODIF instrument were studied statistically in the high-altitude (from 3 up to 11 RE and high-latitude (from 70 to ~90 deg invariant latitude, ILAT polar region. The principal results are: (1 Outflowing O+ ions with more than 1keV are observed above 10 RE geocentric distance and above 85deg ILAT location; (2 at 6-8 RE geocentric distance, the latitudinal distribution of O+ ion outflow is consistent with velocity filter dispersion from a source equatorward and below the spacecraft (e.g. the cusp/cleft; (3 however, at 8-12 RE geocentric distance the distribution of O+ outflows cannot be explained by velocity filter only. The results suggest that additional energization or acceleration processes for outflowing O+ ions occur at high altitudes and high latitudes in the dayside polar region. Keywords. Magnetospheric physics (Magnetospheric configuration and dynamics, Solar wind-magnetosphere interactions

  9. Limnology and cyanobacterial diversity of high altitude lakes of ...

    Indian Academy of Sciences (India)

    Limnological data of four high altitude lakes from the cold desert region of Himachal Pradesh, India, has been correlated with cyanobacterial diversity. Physico-chemical characteristics and nutrient contents of the studied lakes revealed that Sissu Lake is mesotrophic while Chandra Tal, Suraj Tal and Deepak Tal are ...

  10. LIFTING THE DUSTY VEIL WITH NEAR- AND MID-INFRARED PHOTOMETRY. I. DESCRIPTION AND APPLICATIONS OF THE RAYLEIGH-JEANS COLOR EXCESS METHOD

    International Nuclear Information System (INIS)

    Majewski, Steven R.; Zasowski, Gail; Nidever, David L.

    2011-01-01

    The Milky Way (MW) remains a primary laboratory for understanding the structure and evolution of spiral galaxies, but typically we are denied clear views of MW stellar populations at low Galactic latitudes because of extinction by interstellar dust. However, the combination of Two Micron All-Sky Survey (2MASS) near-infrared (NIR) and Spitzer-IRAC mid-infrared (MIR) photometry enables a powerful method for determining the line-of-sight reddening to any star: the sampled wavelengths lie in the Rayleigh-Jeans part of the spectral energy distribution of most stars, where, to first order, all stars have essentially the same intrinsic color. Thus, changes in stellar NIR-MIR colors due to interstellar reddening are readily apparent, and (under an assumed extinction law) the observed colors and magnitudes of stars can be easily and accurately restored to their intrinsic values, greatly increasing their usefulness for Galactic structure studies. In this paper, we explore this 'Rayleigh-Jeans Color Excess' (RJCE) method and demonstrate that use of even a simple variant of the RJCE method based on a single reference color, (H -[4.5μ]), can rather accurately remove dust effects from previously uninterpretable 2MASS color-magnitude diagrams of stars in fields along the heavily reddened Galactic midplane, with results far superior to those derived from application of other dereddening methods. We also show that 'total' Galactic midplane extinction looks rather different from that predicted using 100μ emission maps from the IRAS/ISSA and COBE/DIRBE instruments as presented by Schlegel et al. Instead, the Galactic midplane extinction strongly resembles the distribution of 13 CO (J = 1→0) emission. Future papers will focus on refining the RJCE method and applying the technique to understand better not only dust and its distribution but also the distribution of stars intermixed with the dust in the low-latitude Galaxy.

  11. MEASURING STAR FORMATION RATES AND FAR-INFRARED COLORS OF HIGH-REDSHIFT GALAXIES USING THE CO(7–6) AND [N II] 205 μm LINES

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Nanyao; Zhao, Yinghe; Xu, C. Kevin; Howell, Justin; Mazzarella, Joseph M.; Schulz, Bernhard [Infrared Processing and Analysis Center, California Institute of Technology, MS 100-22, Pasadena, CA 91125 (United States); Gao, Yu; Liu, Lijie [Purple Mountain Observatory, Chinese Academy of Sciences, Nanjing 210008 (China); Díaz-Santos, Tanio; Armus, Lee [Spitzer Science Center, California Institute of Technology, MS 220-6, Pasadena, CA 91125 (United States); Charmandaris, Vassilis [Department of Physics, University of Crete, GR-71003 Heraklion (Greece); Inami, Hanae [National Optical Astronomy Observatory, Tucson, AZ 85719 (United States); Privon, George C. [Departamento de Astronomía, Universidad de Concepción, Casilla 160 C, Concepción (Chile); Lord, Steven D. [The SETI Institute, 189 Bernardo Avenue Suite 100, Mountain View, CA 94043 (United States); Sanders, David B. [Institute for Astronomy, University of Hawaii, 2680 Woodlawn Drive, Honolulu, HI 96822 (United States); Van der Werf, Paul P., E-mail: lu@ipac.caltech.edu [Leiden Observatory, Leiden University, P.O. Box 9513, 2300 RA Leiden (Netherlands)

    2015-03-20

    To better characterize the global star formation activity in a galaxy, one needs to know not only the star formation rate (SFR) but also the rest-frame, far-infrared color (e.g., the 60–100 μm color, C(60/100)) of the dust emission. The latter probes the average intensity of the dust heating radiation field and scales statistically with the effective SFR surface density in star-forming galaxies including (ultra-)luminous infrared galaxies ((U)LIRGs). To this end, here we exploit a new spectroscopic approach involving only two emission lines: CO(7–6) at 372 μm and [N ii] at 205 μm([N ii]{sub 205μm}). For local (U)LIRGs, the ratios of the CO(7–6) luminosity (L{sub CO(7–6)}) to the total infrared luminosity (L{sub IR}; 8–1000 μm) are fairly tightly distributed (to within ∼0.12 dex) and show little dependence on C(60/100). This makes L{sub CO(7–6)} a good SFR tracer, which is less contaminated by active galactic nuclei than L{sub IR} and may also be much less sensitive to metallicity than L{sub CO(1–0)}. Furthermore, the logarithmic [N ii]{sub 205μm}/CO(7–6) luminosity ratio depends fairly strongly (at a slope of ∼ −1.4) on C(60/100), with a modest scatter (∼0.23 dex). This makes it a useful estimator on C(60/100) with an implied uncertainty of ∼0.15 (or ≲4 K in the dust temperature (T{sub dust}) in the case of a graybody emission with T{sub dust} ≳ 30 K and a dust emissivity index β ≥ 1). Our locally calibrated SFR and C(60/100) estimators are shown to be consistent with the published data of (U)LIRGs of z up to ∼6.5.

  12. Oxidative DNA damage and repair in skeletal muscle of humans exposed to high-altitude hypoxia

    DEFF Research Database (Denmark)

    Lundby, Carsten; Pilegaard, Henriette; van Hall, Gerrit

    2003-01-01

    Recent research suggests that high-altitude hypoxia may serve as a model for prolonged oxidative stress in healthy humans. In this study, we investigated the consequences of prolonged high-altitude hypoxia on the basal level of oxidative damage to nuclear DNA in muscle cells, a major oxygen-consuming...

  13. Novel drugs in the management of acute mountain sickness and high altitude pulmonary edema

    OpenAIRE

    Gaurav Sikri, Gaurav; Bhattacharya,Anirban

    2015-01-01

    Gaurav Sikri, Anirban Bhattacharya Department of Physiology, Armed Forces Medical College, Wanowarie, Pune, IndiaWe read with great interest the review article titled “Wilderness medicine at high altitude: recent developments in the field” by Shah et al.1 The authors have comprehensively summarized the recent advances in the field of high altitude medicine relevant to sports and travel medicine. However, Shah et al have described potential drugs for management of high-alti...

  14. Sub-Scale Re-entry Capsule Drop via High Altitude Balloons

    Data.gov (United States)

    National Aeronautics and Space Administration — The project objective is to develop and test a sub-scale version of the Maraia Entry Capsule on a high altitude balloon. The capsule is released at 100,000 ft. The...

  15. High-altitude adaptation of Tibetan chicken from MT-COI and ATP-6 perspective.

    Science.gov (United States)

    Zhao, Xiaoling; Wu, Nan; Zhu, Qing; Gaur, Uma; Gu, Ting; Li, Diyan

    2016-09-01

    The problem of hypoxia adaptation in high altitudes is an unsolved brainteaser in the field of life sciences. As one of the best chicken breeds with adaptability to highland environment, the Tibetan chicken, is genetically different from lowland chicken breeds. In order to gain a better understanding of the mechanism of hypoxic adaptability in high altitude, in the present study, we focused on the MT-COI together with ATP-6 gene to explore the regulatory mechanisms for hypoxia adaptability in Tibet chicken. Here, we sequenced MT-COI of 29 Tibetan chickens and 30 Chinese domestic chickens and ATP-6 gene of 28 Tibetan chickens and 29 Chinese domestic chickens. In MT-COI gene, 9 single nucleotide polymorphisms (SNPs) were detected though none of these was a missense mutation, confirming the fact that MT-COI gene is a largely conservative sequence. In ATP-6 gene, 6 single nucleotide polymorphisms (SNPs) were detected and we found a missense mutation (m.9441G > A) in the ATP-6 gene of Tibetan chicken resulting in an amino acid substitution. Due to the critical role of ATP-6 gene in the proton translocation and energy metabolism, we speculated the possibility of this mutation playing an important role in easier energy conversion and metabolism in Tibetan chickens than Chinese domestic chickens so as to better adapt to the harsh environment of the high-altitude areas. The Median-joining profile also suggested that haplotype Ha2 has the ancestral position to the other haplotypes and has significant relationship with high-altitude adaptation in ATP-6 gene. Therefore, we considered that the polymorphism (m.9441G > A) in the ATP-6 gene may affect the specific functions of ATP-6 enzyme relating to high-altitude adaptation of Tibetan chicken and MT-COI gene is a largely conservative sequence.

  16. Using Lidar and color infrared imagery to successfully measure stand characteristics on the William B. Bankhead National Forest, Alabama

    Science.gov (United States)

    Jeffrey Stephens; Luben Dimov; Callie Schweitzer; Wubishet Tadesse

    2008-01-01

    Light detection and ranging (Lidar) and color infrared imagery (CIR) were used to quantify forest structure and to distinguish deciduous from coniferous trees for selected stands on the William B. Bankhead National Forest in Alabama. Lidar bare ground and vegetation point clouds were used to determine tree heights and tree locations. Lidar accuracy was assessed by...

  17. Flight Control of the High Altitude Wind Power System

    NARCIS (Netherlands)

    Podgaets, A.R.; Ockels, W.J.

    2007-01-01

    Closed loop Laddermill flight control problem is considered in this paper. Laddermill is a high altitude kites system for energy production. The kites have been simulated as rigid bodies and the cable as a thin elastic line. Euler angles and cable speed are controls. Flight control is written as a

  18. MAPPING SPATIAL/TEMPORAL DISTRIBUTIONS OF GREEN MACROALGAE IN A PACIFIC NORTHWEST COASTAL ESTUARY VIA SMALL FORMAT COLOR INFRARED AERIAL PHOTOGRAPHY

    Science.gov (United States)

    A small format 35 mm hand-held camera with color infrared slide film was used to map blooms of benthic green macroalgae upon mudflats of Yaquina Bay estuary on the central Oregon coast, U.S.A. Oblique photographs were taken during a series of low tide events, when the intertidal...

  19. Predator-prey interaction reveals local effects of high-altitude insect migration

    Science.gov (United States)

    High-altitude nocturnal insect migrations represent significant pulses of resources, yet are difficult to study and poorly understood. Predator-prey interactions, specifically migratory moth consumption by high-flying bats, potentially reveal flows of migratory insects across a landscape. In North...

  20. Key issues of ultraviolet radiation of OH at high altitudes

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Yuhuai; Wan, Tian; Jiang, Jianzheng; Fan, Jing [State Key Laboratory of High Temperature Gasdynamics, Institute of Mechanics, Chinese Academy of Sciences, Beijing 100190 (China)

    2014-12-09

    Ultraviolet (UV) emissions radiated by hydroxyl (OH) is one of the fundamental elements in the prediction of radiation signature of high-altitude and high-speed vehicle. In this work, the OH A{sup 2}Σ{sup +}→X{sup 2}Π ultraviolet emission band behind the bow shock is computed under the experimental condition of the second bow-shock ultraviolet flight (BSUV-2). Four related key issues are discussed, namely, the source of hydrogen element in the high-altitude atmosphere, the formation mechanism of OH species, efficient computational algorithm of trace species in rarefied flows, and accurate calculation of OH emission spectra. Firstly, by analyzing the typical atmospheric model, the vertical distributions of the number densities of different species containing hydrogen element are given. According to the different dominating species containing hydrogen element, the atmosphere is divided into three zones, and the formation mechanism of OH species is analyzed in the different zones. The direct simulation Monte Carlo (DSMC) method and the Navier-Stokes equations are employed to compute the number densities of the different OH electronically and vibrationally excited states. Different to the previous work, the trace species separation (TSS) algorithm is applied twice in order to accurately calculate the densities of OH species and its excited states. Using a non-equilibrium radiation model, the OH ultraviolet emission spectra and intensity at different altitudes are computed, and good agreement is obtained with the flight measured data.

  1. High Altitude Remains Associated with Elevated Suicide Rates after Adjusting for Socioeconomic Status: A Study from South Korea

    OpenAIRE

    Kim, Jaelim; Choi, Nari; Lee, Yu-Jin; An, Hyonggin; Kim, Namkug; Yoon, Ho-Kyoung; Lee, Heon-Jeong

    2014-01-01

    There have been several studies supporting a possible relationship between high suicide rate and high altitude. However socioeconomic status may confound this association because low socioeconomic status, which is known to be related to a high suicide rate, is also associated with living at high altitude. This study aims to explore whether the relationship between high altitude and high suicide rate remains after adjusting for socioeconomic status in South Korea. We collected demographic data...

  2. Ben Macdhui High Altitude Trace Gas and Aerosol Transport Experiment

    CSIR Research Space (South Africa)

    Piketh, SJ

    1999-01-01

    Full Text Available The Ben Macdhui High Altitude Aerosol and Trace Gas Transport Experiment (BHATTEX) was started to characterize the nature and magnitude of atmospheric, aerosol and trace gas transport paths recirculation over and exiting from southern Africa...

  3. Evolved changes in the intracellular distribution and physiology of muscle mitochondria in high-altitude native deer mice.

    Science.gov (United States)

    Mahalingam, Sajeni; McClelland, Grant B; Scott, Graham R

    2017-07-15

    Mitochondrial function changes over time at high altitudes, but the potential benefits of these changes for hypoxia resistance remains unclear. We used high-altitude-adapted populations of deer mice, which exhibit enhanced aerobic performance in hypoxia, to examine whether changes in mitochondrial physiology or intracellular distribution in the muscle contribute to hypoxia resistance. Permeabilized muscle fibres from the gastrocnemius muscle had higher respiratory capacities in high-altitude mice than in low-altitude mice. Highlanders also had higher mitochondrial volume densities, due entirely to an enriched abundance of subsarcolemmal mitochondria, such that more mitochondria were situated near the cell membrane and adjacent to capillaries. There were several effects of hypoxia acclimation on mitochondrial function, some of which were population specific, but they differed from the evolved changes in high-altitude natives, which probably provide a better indication of adaptive traits that improve performance and hypoxia resistance at high altitudes. High-altitude natives that have evolved to live in hypoxic environments provide a compelling system to understand how animals can overcome impairments in oxygen availability. We examined whether these include changes in mitochondrial physiology or intracellular distribution that contribute to hypoxia resistance in high-altitude deer mice (Peromyscus maniculatus). Mice from populations native to high and low altitudes were born and raised in captivity, and as adults were acclimated to normoxia or hypobaric hypoxia (equivalent to 4300 m elevation). We found that highlanders had higher respiratory capacities in the gastrocnemius (but not soleus) muscle than lowlanders (assessed using permeabilized fibres with single or multiple inputs to the electron transport system), due in large part to higher mitochondrial volume densities in the gastrocnemius. The latter was attributed to an increased abundance of subsarcolemmal

  4. NEURO ENGINEERING TECHNOLOGY TO ACCELERATE THE HUMAN ADAPTATION TO HIGH ALTITUDE HYPOXIA

    Directory of Open Access Journals (Sweden)

    Mukhamed T. Shaov

    2018-01-01

    Full Text Available Abstract. The aim is to study the influence of neuro-information signals modulated by pulse hypoxia on the rhythm of cardiac contractions in low-mountain and high-mountain conditions. Methods. Heart rate was measured using the pulse oxymetry device ELOX-01M2. The impact analysis of information-wave signals was carried out with the help of the neuro-protector "Anthropotherapist", non-invasively (remotely at a distance of up to 5 meters for 5 min. /day during 10 days. The investigations were carried out in lowmountain conditions (city of Nalchik, 550 m above sea level and highlands, Mount Elbrus (site of "Garabashi", 3780 m. above sea level. Participants in the study were divided into groups: control group – 18 participants; experimental group - 18 participants. In the low-mountain and high-mountain conditions, the control group was not affected by the neuro-protector. In high-mountain conditions, the participants in the control group experienced only the effects of high-altitude hypoxia sessions. The experimental group was exposed to the neuro-information signals from the neuro-protector. High-altitude studies were carried out in the following mode: heart rate was recorded at the altitudes of Nalchik - exit to Elbrus – on the way to the site of "Garabashi" - return route to Nalchik. Results. It was found that with frequency exposure, there is a significant decrease and fluctuations in heart rate in low-mountain inhabitants. The stability of these changes in the rhythm of cardiac activity can also be seen in conditions of high-altitude hypoxia. Conclusion. Consequently, the proposed mode of frequency impact, implemented using the "Anthropotherapist" neuro-protector technology, can form a stage of adaptation to hypoxia and unfavorable climatic and environmental factors.

  5. Phenylethanoid glycosides of Pedicularis muscicola Maxim ameliorate high altitude-induced memory impairment.

    Science.gov (United States)

    Zhou, Baozhu; Li, Maoxing; Cao, Xinyuan; Zhang, Quanlong; Liu, Yantong; Ma, Qiang; Qiu, Yan; Luan, Fei; Wang, Xianmin

    2016-04-01

    Exposure to hypobaric hypoxia causes oxidative stress, neuronal degeneration and apoptosis that leads to memory impairment. Though oxidative stress contributes to neuronal degeneration and apoptosis in hypobaric hypoxia, the ability for phenylethanoid glycosides of Pedicularis muscicola Maxim (PhGs) to reverse high altitude memory impairment has not been studied. Rats were supplemented with PhGs orally for a week. After the fourth day of drug administration, rats were exposed to a 7500 m altitude simulation in a specially designed animal decompression chamber for 3 days. Spatial memory was assessed by the 8-arm radial maze test before and after exposure to hypobaric hypoxia. Histological assessment of neuronal degeneration was performed by hematoxylin-eosin (HE) staining. Changes in oxidative stress markers and changes in the expression of the apoptotic marker, caspase-3, were assessed in the hippocampus. Our results demonstrated that after exposure to hypobaric hypoxia, PhGs ameliorated high altitude memory impairment, as shown by the decreased values obtained for reference memory error (RME), working memory error (WME), and total error (TE). Meanwhile, administration of PhGs decreased hippocampal reactive oxygen species levels and consequent lipid peroxidation by elevating reduced glutathione levels and enhancing the free radical scavenging enzyme system. There was also a decrease in the number of pyknotic neurons and a reduction in caspase-3 expression in the hippocampus. These findings suggest that PhGs may be used therapeutically to ameliorate high altitude memory impairment. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. Laboratory Simulations of Haze Formation in the Atmospheres of Super-Earths and Mini-Neptunes: Particle Color and Size Distribution

    Science.gov (United States)

    He, Chao; Hörst, Sarah M.; Lewis, Nikole K.; Yu, Xinting; Moses, Julianne I.; Kempton, Eliza M.-R.; McGuiggan, Patricia; Morley, Caroline V.; Valenti, Jeff A.; Vuitton, Véronique

    2018-03-01

    Super-Earths and mini-Neptunes are the most abundant types of planets among the ∼3500 confirmed exoplanets, and are expected to exhibit a wide variety of atmospheric compositions. Recent transmission spectra of super-Earths and mini-Neptunes have demonstrated the possibility that exoplanets have haze/cloud layers at high altitudes in their atmospheres. However, the compositions, size distributions, and optical properties of these particles in exoplanet atmospheres are poorly understood. Here, we present the results of experimental laboratory investigations of photochemical haze formation within a range of planetary atmospheric conditions, as well as observations of the color and size of produced haze particles. We find that atmospheric temperature and metallicity strongly affect particle color and size, thus altering the particles’ optical properties (e.g., absorptivity, scattering, etc.); on a larger scale, this affects the atmospheric and surface temperature of the exoplanets, and their potential habitability. Our results provide constraints on haze formation and particle properties that can serve as critical inputs for exoplanet atmosphere modeling, and guide future observations of super-Earths and mini-Neptunes with the Transiting Exoplanet Survey Satellite, the James Webb Space Telescope, and the Wide-Field Infrared Survey Telescope.

  7. CARETS: A prototype regional environmental information system. Volume 6: Cost, accuracy and consistency comparisons of land use maps made from high-altitude aircraft photography and ERTS imagery

    Science.gov (United States)

    Alexander, R. H. (Principal Investigator); Fitzpatrick, K. A.

    1975-01-01

    The author has identified the following significant results. Level 2 land use maps produced at three scales (1:24,000, 1:100,000, and 1:250,000) from high altitude photography were compared with each other and with point data obtained in the field. The same procedures were employed to determine the accuracy of the Level 1 land use maps produced at 1:250,000 from high altitude photography and color composite ERTS imagery. Accuracy of the Level 2 maps was 84.9 percent at 1:24,000, 77.4 percent at 1:100,000 and 73.0 percent at 1:250,000. Accuracy of the Level 1 1:250,000 maps was 76.5 percent for aerial photographs and 69.5 percent for ERTS imagery. The cost of Level 2 land use mapping at 1:24,000 was found to be high ($11.93 per sq km). The cost of mapping at 1:100,000 ($1.75) was about two times as expensive as mapping at 1:250,000 ($.88), and the accuracy increased by only 4.4 percent.

  8. Comparative study of acetazolamide and spironolactone on body fluid compartments on induction to high altitude

    Science.gov (United States)

    Singh, M. V.; Jain, S. C.; Rawal, S. B.; Divekar, H. M.; Parshad, Rajinder; Tyagi, A. K.; Sinha, K. C.

    1986-03-01

    Studies were conducted on 29 male healthy subjects having no previous experience of living at high altitude. These subjects were divided into three groups, i.e., subjects treated with placebo, acetazolamide and spironolactone. These subjects were first studied in Delhi. The drug schedule was started 24 hour prior to the airlift of these subjects to an altitude of 3,500 m and was continued for 48 hour after arrival at high altitude. Total body water, extra cellular water, plasma volume, blood electrolytes, pH, pO2, pCO2 and blood viscosity were determined on 3rd and 12th day of their stay at high altitude. Total body water, extra cellular water intracellular water and plasma volume decreased on high altitude exposure. There was a further slight decrease in these compartments with acetazolamide and spironolactone. It was also observed that spironolactone drives out more water from the extracellular compartment. Loss of plasma water was also confirmed by increased plasma osmolality. Increase in arterial blood pH was noticed on hypoxic exposure but the increase was found less in acetazolamide and spironolactone cases. This decrease in pH is expected to result in better oxygen delivery to the tissues at the low oxygen tension. It was also confirmed because blood pO2 increased in both the groups. No significant change in plasma electrolytes was observed in subjects of various groups. Blood viscosity slightly increased on exposure to high altitude. The degree of rise was found less in the group treated with spironolactone. This study suggests that both the drugs are likely to be beneficial in ameliorating/prevention of AMS syndrome.

  9. Rhodiola crenulata- and Cordyceps sinensis-based supplement boosts aerobic exercise performance after short-term high altitude training.

    Science.gov (United States)

    Chen, Chung-Yu; Hou, Chien-Wen; Bernard, Jeffrey R; Chen, Chiu-Chou; Hung, Ta-Cheng; Cheng, Lu-Ling; Liao, Yi-Hung; Kuo, Chia-Hua

    2014-09-01

    High altitude training is a widely used strategy for improving aerobic exercise performance. Both Rhodiola crenulata (R) and Cordyceps sinensis (C) supplements have been reported to improve exercise performance. However, it is not clear whether the provision of R and C during high altitude training could further enhance aerobic endurance capacity. In this study, we examined the effect of R and C based supplementation on aerobic exercise capacity following 2-week high altitude training. Alterations to autonomic nervous system activity, circulatory hormonal, and hematological profiles were investigated. Eighteen male subjects were divided into two groups: Placebo (n=9) and R/C supplementation (RC, n=9). Both groups received either RC (R: 1400 mg+C: 600 mg per day) or the placebo during a 2-week training period at an altitude of 2200 m. After 2 weeks of altitude training, compared with Placebo group, the exhaustive run time was markedly longer (Placebo: +2.2% vs. RC: +5.7%; paltitude training (paltitude training provides greater training benefits in improving aerobic performance. This beneficial effect of RC treatment may result from better maintenance of PNS activity and accelerated physiological adaptations during high altitude training.

  10. Circulation, metabolism, and ventilation during prolonged exposure to carbon monoxide and to high altitude

    Energy Technology Data Exchange (ETDEWEB)

    Klausen, K.; Rasmussen, B; Gjellerod, H.; Madsen, H.; Petersen, E.

    1968-01-01

    Eight volunteers were exposed to CO (13% COHb) or high altitude (3454 m). There was no change in circulation, metabolism, or ventilation during CO exposure. With similar arterial O/sub 2/ concentration from high-altitude, V/sub e/ (BTPS) increased, Pa/sub CO/sub 2// decreased. Regulating mechanisms respond to a decrease in Pa/sub CO/sub 2// rather than a gereral lack in tissue O/sub 2/ per se.

  11. Near-infrared observations of IRAS minisurvey galaxies

    International Nuclear Information System (INIS)

    Carico, D.P.; Soifer, B.T.; Elias, J.H.; Matthews, K.; Neugebauer, G.; Beichman, C.; Persson, C.J.; Persson, S.E.

    1987-01-01

    Near infrared photometry at J, H, and K was obtained for 82 galaxies from the IRAS minisurvey. The near infrared colors of these galaxies cover a larger range in J-H and H-K than do normal field spiral galaxies, and evidence is presented of a tighter correlation between the near and far infrared emission in far infrared bright galaxies than exists between the far infrared and the visible emission. These results suggest the presence of dust in the far infrared bright galaxies, with hot dust emission contributing to the 2.2 micron emission, and extinction by dust affecting both the near infrared colors and the visible luminosities. In addition, there is some indication that the infrared emission in many of the minisurvey galaxies is coming from a strong nuclear component

  12. Increase of cerebral blood flow at high altitude

    DEFF Research Database (Denmark)

    Lassen, N A

    1992-01-01

    but rather somewhat sharpened over five days at almost 4000 meters of altitude. This, along with other evidence, shows that CBF does not in itself adapt to chronic hypoxia. Nevertheless, a decrease in CBF is seen over days at constant altitude primarily due to increase in the hematocrit. The cerebral...

  13. Usefulness of training camps at high altitude for well-trained adolescents

    Directory of Open Access Journals (Sweden)

    Jiří Suchý

    2015-03-01

    Full Text Available Objective: Opinions on the suitability of sports training at altitudes of 1800-2200 m above sea level (ASL for increasing performance in youth are not unanimous. The objective of this study was to test the influence of a ten day altitude training camp on performance in well-trained adolescent cross-country skiers. Methods: A running test of 3 × 2 km (aerobic, anaerobic and critical intensity was used with a rest interval of 10 minutes. The test was performed 4 times - an initial test at a lowland (900 m ASL prior to departure for altitude, two tests at altitude (1850 m ASL, a final test ten days after returning to lower altitudes. The aerobic, anaerobic and critical load intensities were set by graded a load test. For all individual tests, the participants maintained the same heart rate individually defined for the various segments using a heart rate monitor. Changes in speed between the tests were compared. The body's internal response was also monitored by the concentration of lactate (2 and 8 minutes after each exertion. Participants: Well-trained adolescent cross-country skiers (N = 11, age: 14.4 ± 1.2 years, weight: 54.4 ± 8.6 kg, height: 170 ± 7 cm, fat: 13 ± 2.6%. Results: The average times attained in the first altitude test for aerobic and anaerobic load were higher (p < .05 than in the entry test at low altitude. In the second altitude test the average times for all intensities were significantly (p < .05 higher than in the first altitude test. In the tests after returning to the lower altitudes the times attained for all intensities were on average higher than at altitude. The average lactate concentration levels following the various intensities were similar (p > .05. The dynamics of the cool-down monitored via the lactate value at the eighth minute after completing the relevant segment showed that at altitude the adolescents cooled down significantly (p < .05 slower rate following the aerobic and anaerobic intensity than at

  14. The STAR Data Reporting Guidelines for Clinical High Altitude Research.

    Science.gov (United States)

    Brodmann Maeder, Monika; Brugger, Hermann; Pun, Matiram; Strapazzon, Giacomo; Dal Cappello, Tomas; Maggiorini, Marco; Hackett, Peter; Bärtsch, Peter; Swenson, Erik R; Zafren, Ken

    2018-03-01

    Brodmann Maeder, Monika, Hermann Brugger, Matiram Pun, Giacomo Strapazzon, Tomas Dal Cappello, Marco Maggiorini, Peter Hackett, Peter Baärtsch, Erik R. Swenson, Ken Zafren (STAR Core Group), and the STAR Delphi Expert Group. The STARdata reporting guidelines for clinical high altitude research. High AltMedBiol. 19:7-14, 2018. The goal of the STAR (STrengthening Altitude Research) initiative was to produce a uniform set of key elements for research and reporting in clinical high-altitude (HA) medicine. The STAR initiative was inspired by research on treatment of cardiac arrest, in which the establishment of the Utstein Style, a uniform data reporting protocol, substantially contributed to improving data reporting and subsequently the quality of scientific evidence. The STAR core group used the Delphi method, in which a group of experts reaches a consensus over multiple rounds using a formal method. We selected experts in the field of clinical HA medicine based on their scientific credentials and identified an initial set of parameters for evaluation by the experts. Of 51 experts in HA research who were identified initially, 21 experts completed both rounds. The experts identified 42 key parameters in 5 categories (setting, individual factors, acute mountain sickness and HA cerebral edema, HA pulmonary edema, and treatment) that were considered essential for research and reporting in clinical HA research. An additional 47 supplemental parameters were identified that should be reported depending on the nature of the research. The STAR initiative, using the Delphi method, identified a set of key parameters essential for research and reporting in clinical HA medicine.

  15. The role of oxygen-increased respirator in humans ascending to high altitude

    Directory of Open Access Journals (Sweden)

    Shen Guanghao

    2012-08-01

    Full Text Available Abstract Background Acute mountain sickness (AMS is common for people who live in low altitude areas ascending to the high altitude. Many instruments have been developed to treat mild cases of AMS. However, long-lasting and portable anti-hypoxia equipment for individual is not yet available. Methods Oxygen-increased respirator (OIR has been designed to reduce the risk of acute mountain sickness in acute exposure to low air pressure. It can increase the density of oxygen by increasing total atmospheric pressure in a mask. Male subjects were screened, and eighty-eight were qualified to perform the experiments. The subjects were divided into 5 groups and were involved in some of the tests at 4 different altitudes (Group 1, 2: 3700 m; Group 3,4,5: 4000 m, 4700 m, 5380 m with and without OIR. These tests include heart rate, saturation of peripheral oxygen (SpO2, malondialdehyde (MDA, superoxide dismutase (SOD, blood lactate (BLA and PWC (physical work capacity -170. Results The results showed that higher SpO2, lower heart rate (except during exercise and better recovery of heart rate were observed from all the subjects ’with OIR’ compared with ’without OIR’ (P Conclusions We suggested that OIR may play a useful role in protecting people ascending to high altitude before acclimatization.

  16. Pathophysiology of acute mountain sickness and high altitude pulmonary oedema

    DEFF Research Database (Denmark)

    Sutton, J R; Lassen, N

    1979-01-01

    We review the evidence that acute mountain sickness (AMS) and high altitude pulmonary oedema (HAPO) occur together more often than is realized. We hypothesize that AMS and HAPO have a common pathophysiological basis: both are due to increased pressure and flow in the microcirculation, causing...

  17. AKARI INFRARED CAMERA SURVEY OF THE LARGE MAGELLANIC CLOUD. II. THE NEAR-INFRARED SPECTROSCOPIC CATALOG

    International Nuclear Information System (INIS)

    Shimonishi, Takashi; Onaka, Takashi; Kato, Daisuke; Sakon, Itsuki; Ita, Yoshifusa; Kawamura, Akiko; Kaneda, Hidehiro

    2013-01-01

    We performed a near-infrared spectroscopic survey toward an area of ∼10 deg 2 of the Large Magellanic Cloud (LMC) with the infrared satellite AKARI. Observations were carried out as part of the AKARI Large-area Survey of the Large Magellanic Cloud (LSLMC). The slitless multi-object spectroscopic capability of the AKARI/IRC enabled us to obtain low-resolution (R ∼ 20) spectra in 2-5 μm for a large number of point sources in the LMC. As a result of the survey, we extracted about 2000 infrared spectra of point sources. The data are organized as a near-infrared spectroscopic catalog. The catalog includes various infrared objects such as young stellar objects (YSOs), asymptotic giant branch (AGB) stars, supergiants, and so on. It is shown that 97% of the catalog sources have corresponding photometric data in the wavelength range from 1.2 to 11 μm, and 67% of the sources also have photometric data up to 24 μm. The catalog allows us to investigate near-infrared spectral features of sources by comparison with their infrared spectral energy distributions. In addition, it is estimated that about 10% of the catalog sources are observed at more than two different epochs. This enables us to study a spectroscopic variability of sources by using the present catalog. Initial results of source classifications for the LSLMC samples are presented. We classified 659 LSLMC spectra based on their near-infrared spectral features by visual inspection. As a result, it is shown that the present catalog includes 7 YSOs, 160 C-rich AGBs, 8 C-rich AGB candidates, 85 O-rich AGBs, 122 blue and yellow supergiants, 150 red super giants, and 128 unclassified sources. Distributions of the classified sources on the color-color and color-magnitude diagrams are discussed in the text. Continuous wavelength coverage and high spectroscopic sensitivity in 2-5 μm can only be achieved by space observations. This is an unprecedented large-scale spectroscopic survey toward the LMC in the near-infrared

  18. The paradox of extreme high-altitude migration in bar-headed geese Anser indicus

    Science.gov (United States)

    Hawkes, L. A.; Balachandran, S.; Batbayar, N.; Butler, P. J.; Chua, B.; Douglas, D. C.; Frappell, P. B.; Hou, Y.; Milsom, W. K.; Newman, S. H.; Prosser, D. J.; Sathiyaselvam, P.; Scott, G. R.; Takekawa, J. Y.; Natsagdorj, T.; Wikelski, M.; Witt, M. J.; Yan, B.; Bishop, C. M.

    2013-01-01

    Bar-headed geese are renowned for migratory flights at extremely high altitudes over the world's tallest mountains, the Himalayas, where partial pressure of oxygen is dramatically reduced while flight costs, in terms of rate of oxygen consumption, are greatly increased. Such a mismatch is paradoxical, and it is not clear why geese might fly higher than is absolutely necessary. In addition, direct empirical measurements of high-altitude flight are lacking. We test whether migrating bar-headed geese actually minimize flight altitude and make use of favourable winds to reduce flight costs. By tracking 91 geese, we show that these birds typically travel through the valleys of the Himalayas and not over the summits. We report maximum flight altitudes of 7290 m and 6540 m for southbound and northbound geese, respectively, but with 95 per cent of locations received from less than 5489 m. Geese travelled along a route that was 112 km longer than the great circle (shortest distance) route, with transit ground speeds suggesting that they rarely profited from tailwinds. Bar-headed geese from these eastern populations generally travel only as high as the terrain beneath them dictates and rarely in profitable winds. Nevertheless, their migration represents an enormous challenge in conditions where humans and other mammals are only able to operate at levels well below their sea-level maxima. PMID:23118436

  19. SEASONAL DISAPPEARANCE OF FAR-INFRARED HAZE IN TITAN'S STRATOSPHERE

    Energy Technology Data Exchange (ETDEWEB)

    Jennings, Donald E.; Anderson, C. M.; Flasar, F. M.; Cottini, V. [Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Samuelson, R. E.; Nixon, C. A.; Kunde, V. G.; Achterberg, R. K. [Department of Astronomy, University of Maryland, College Park, MD 20742 (United States); De Kok, R. [SRON Netherlands Institute for Space Research, Sorbonnelaan 2, 3584 CA Utrecht (Netherlands); Coustenis, A.; Vinatier, S. [LESIA, Observatoire de Paris-Meudon, 92195 Meudon Cedex (France); Calcutt, S. B., E-mail: donald.e.jennings@nasa.gov [Department of Physics, University of Oxford, Parks Road, Oxford OX1 3PU (United Kingdom)

    2012-07-20

    A far-infrared emission band attributed to volatile or refractory haze in Titan's stratosphere has been decreasing in intensity since Cassini's arrival in 2004. The 220 cm{sup -1} feature, first seen by the Voyager Infrared Interferometer Spectrometer, has only been found in Titan's winter polar region. The emission peaks at about 140 km altitude near the winter stratospheric temperature minimum. Observations recorded over the period 2004-2012 by the Composite Infrared Spectrometer on Cassini show a decrease in the intensity of this feature by about a factor of four. Possible seasonal causes of this decline are an increase in photolytic destruction of source chemicals at high altitude, a lessening of condensation as solar heating increased, or a weakening of downwelling of vapors. As of early 2012, the 220 cm{sup -1} haze has not yet been detected in the south. The haze composition is unknown, but its decrease is similar to that of HC{sub 3}N gas in Titan's polar stratosphere, pointing to a nitrile origin.

  20. Increased Cardiometabolic Risk and Worsening Hypoxemia at High Altitude

    OpenAIRE

    Miele, Catherine H.; Schwartz, Alan R.; Gilman, Robert H.; Pham, Luu; Wise, Robert A.; Davila-Roman, Victor G.; Jun, Jonathan C.; Polotsky, Vsevolod Y.; Miranda, J. Jaime; Leon-Velarde, Fabiola; Checkley, William

    2016-01-01

    Miele, Catherine H., Alan R. Schwartz, Robert H. Gilman, Luu Pham, Robert A. Wise, Victor G. Davila-Roman, Jonathan C. Jun, Vsevolod Y. Polotsky, J. Jaime Miranda, Fabiola Leon-Velarde, and William Checkley. Increased cardiometabolic risk and worsening hypoxemia at high altitude. High Alt Med Biol. 17:93���100, 2016.���Metabolic syndrome, insulin resistance, diabetes, and dyslipidemia are associated with an increased risk of cardiovascular disease. While excessive erythrocytosis is associated...

  1. Perseus A High Altitude Remotely Piloted Aircraft being Towed in Flight

    Science.gov (United States)

    1994-01-01

    Perseus A, a remotely piloted, high-altitude research vehicle designed by Aurora Flight Sciences Corp., takes off from Rogers Dry Lake at the Dryden Flight Research Center, Edwards, California. The Perseus was towed into the air by a ground vehicle. At about 700 ft. the aircraft was released and the engine turned the propeller to take the plane to its desired altitude. Perseus B is a remotely piloted aircraft developed as a design-performance testbed under NASA's Environmental Research Aircraft and Sensor Technology (ERAST) project. Perseus is one of several flight vehicles involved in the ERAST project. A piston engine, propeller-powered aircraft, Perseus was designed and built by Aurora Flight Sciences Corporation, Manassas, Virginia. The objectives of Perseus B's ERAST flight tests have been to reach and maintain horizontal flight above altitudes of 60,000 feet and demonstrate the capability to fly missions lasting from 8 to 24 hours, depending on payload and altitude requirements. The Perseus B aircraft established an unofficial altitude record for a single-engine, propeller-driven, remotely piloted aircraft on June 27, 1998. It reached an altitude of 60,280 feet. In 1999, several modifications were made to the Perseus aircraft including engine, avionics, and flight-control-system improvements. These improvements were evaluated in a series of operational readiness and test missions at the Dryden Flight Research Center, Edwards, California. Perseus is a high-wing monoplane with a conventional tail design. Its narrow, straight, high-aspect-ratio wing is mounted atop the fuselage. The aircraft is pusher-designed with the propeller mounted in the rear. This design allows for interchangeable scientific-instrument payloads to be placed in the forward fuselage. The design also allows for unobstructed airflow to the sensors and other devices mounted in the payload compartment. The Perseus B that underwent test and development in 1999 was the third generation of the

  2. a Study of Vibrational Mode Coupling in 2-FLUOROETHANOL and 1,2-DIFLUOROETHANE Using High-Resolution Infrared Spectroscopy.

    Science.gov (United States)

    Mork, Steven Wayne

    High resolution infrared spectroscopy was used to examine intramolecular vibrational interactions in 2 -fluoroethanol (2FE) and 1,2-difluoroethane (DFE). A high resolution infrared spectrophotometer capable of better than 10 MHz spectral resolution was designed and constructed. The excitation source consists of three lasers: an argon-ion pumped dye laser which pumps a color -center laser. The infrared beam from the color-center laser is used to excite sample molecules which are rotationally and vibrationally cooled in a supersonic molecular beam. Rovibrational excitation of the sample molecules is detected by monitoring the kinetic energy of the molecular beam with a bolometer. The high resolution infrared spectrum of 2FE was collected and analyzed over the 2977-2990 cm^ {-1}^ectral region. This region contains the asymmetric CH stretch on the fluorinated carbon. The spectrum revealed extensive perturbations in the rotational fine structure. Analysis of these perturbations has provided a quantitative measure of selective vibrational mode coupling between the C-H stretch and its many neighboring dark vibrational modes. Interestingly, excitation of the C-H stretch is known to induce a photoisomerization reaction between 2FE's Gg^' and Tt conformers. Implications of the role of mode coupling in the reaction mechanism are also addressed. Similarly, the high resolution infrared spectrum of DFE was collected and analyzed over the 2978-2996 cm ^{-1}^ectral region. This region contains the symmetric combination of asymmetric C-H stretches in DFE. Perturbations in the rotational fine structure indicate vibrational mode coupling to a single dark vibrational state. The dark state is split by approximately 19 cm^{-1} due to tunneling between two identical gauche conformers. The coupling mechanism is largely anharmonic with a minor component of B/C-plane Coriolis coupling. Effects of centrifugal distortion along the molecular A-axis are also observed. The coupled vibrational

  3. Integrated Modelling of an Unmanned High-Altitude Solar-Powered Aircraft for Control Law Design Analysis

    OpenAIRE

    Klöckner, Andreas; Leitner, Martin; Schlabe, Daniel; Looye, Gertjan

    2013-01-01

    Solar-powered high-altitude unmanned platforms are highly optimized and integrated aircraft. In order to account for the complex, multi-physical interactions between their systems, we propose using integrated simulation models throughout the aircraft’s life cycle. Especially small teams with limited ressources should benefit from this approach. In this paper, we describe our approach to an integrated model of the Electric High-Altitude Solar-Powered Aircraft ELHASPA. It includes aspects of th...

  4. Isothermal pumping analysis for high-altitude tethered balloons.

    Science.gov (United States)

    Kuo, Kirsty A; Hunt, Hugh E M

    2015-06-01

    High-altitude tethered balloons have potential applications in communications, surveillance, meteorological observations and climate engineering. To maintain balloon buoyancy, power fuel cells and perturb atmospheric conditions, fluids could be pumped from ground level to altitude using the tether as a hose. This paper examines the pumping requirements of such a delivery system. Cases considered include delivery of hydrogen, sulfur dioxide (SO2) and powders as fluid-based slurries. Isothermal analysis is used to determine the variation of pressures and velocities along the pipe length. Results show that transport of small quantities of hydrogen to power fuel cells and maintain balloon buoyancy can be achieved at pressures and temperatures that are tolerable in terms of both the pipe strength and the current state of pumping technologies. To avoid solidification, transport of SO2 would require elevated temperatures that cannot be tolerated by the strength fibres in the pipe. While the use of particle-based slurries rather than SO2 for climate engineering can reduce the pipe size significantly, the pumping pressures are close to the maximum bursting pressure of the pipe.

  5. Human nutrition in cold and high terrestrial altitudes

    Science.gov (United States)

    Srivastava, K. K.; Kumar, Ratan

    1992-03-01

    The calorie and nutritional requirements for a man working in an alien hostile environment of cold regions and high altitude are described and compared to those of normal requirements. Carbohydrates, fats and vitamins fulfilling the caloric and nutritional requirements are generally available in adequate amounts except under conditions of appetite loss. However, the proteins and amino acids should be provided in such a way as to meet the altered behavioral and metabolic requirements. Work in extreme cold requires fulfilling enhanced calorie needs. In high mountainous regions, cold combined with hypoxia produced loss of appetite and necessitated designing of special foods.

  6. Infrared galaxies in the IRAS minisurvey

    Science.gov (United States)

    Soifer, B. T.; Neugebauer, G.; Rowan-Robinson, M.; Clegg, P. E.; Emerson, J. P.; Houck, J. R.; De Jong, T.; Aumann, H. H.; Beichman, C. A.; Boggess, N.

    1984-01-01

    A total of 86 galaxies have been detected at 60 microns in the high galactic latitude portion of the IRAS minisurvey. The surface density of detected galaxies with flux densities greater than 0.5 Jy is 0.25 sq deg. Virtually all the galaxies detected are spiral galaxies and have an infrared to blue luminosity ratio ranging from 50 to 0.5. For the infrared-selected sample, no obvious correlation exists between infrared excess and color temperature. The infrared flux from 10 to 100 microns contributes approximately 5 percent of the blue luminosity for galaxies in the magnitude range 14 less than m(pg) less than 18 mag. The fraction of interacting galaxies is between one-eighth and one-fourth of the sample.

  7. Short-term adaptation and chronic cardiac remodelling to high altitude in lowlander natives and Himalayan Sherpa.

    Science.gov (United States)

    Stembridge, Mike; Ainslie, Philip N; Shave, Rob

    2015-11-01

    What is the topic of this review? At high altitude, the cardiovascular system must adapt in order to meet the metabolic demand for oxygen. This review summarizes recent findings relating to short-term and life-long cardiac adaptation to high altitude in the context of exercise capacity. What advances does it highlight? Both Sherpa and lowlanders exhibit smaller left ventricular volumes at high altitude; however, myocardial relaxation, as evidenced by diastolic untwist, is reduced only in Sherpa, indicating that short-term hypoxia does not impair diastolic relaxation. Potential remodelling of systolic function, as evidenced by lower left ventricular systolic twist in Sherpa, may facilitate the requisite sea-level mechanical reserve required during exercise, although this remains to be confirmed. Both short-term and life-long high-altitude exposure challenge the cardiovascular system to meet the metabolic demand for O2 in a hypoxic environment. As the demand for O2 delivery increases during exercise, the circulatory component of oxygen transport is placed under additional stress. Acute adaptation and chronic remodelling of cardiac structure and function may occur to facilitate O2 delivery in lowlanders during sojourn to high altitude and in permanent highland residents. However, our understanding of cardiac structural and functional adaption in Sherpa remains confined to a higher maximal heart rate, lower pulmonary vascular resistance and no differences in resting cardiac output. Ventricular form and function are intrinsically linked through the left ventricular (LV) mechanics that facilitate efficient ejection, minimize myofibre stress during contraction and aid diastolic recoil. Recent examination of LV mechanics has allowed detailed insight into fundamental cardiac adaptation in high-altitude Sherpa. In this symposium report, we review recent advances in our understanding of LV function in both lowlanders and Sherpa at rest and discuss the potential consequences

  8. Aero-thermo-dynamic analysis of the Spaceliner-7.1 vehicle in high altitude flight

    Science.gov (United States)

    Zuppardi, Gennaro; Morsa, Luigi; Sippel, Martin; Schwanekamp, Tobias

    2014-12-01

    SpaceLiner, designed by DLR, is a visionary, extremely fast passenger transportation concept. It consists of two stages: a winged booster, a vehicle. After separation of the two stages, the booster makes a controlled re-entry and returns to the launch site. According to the current project, version 7-1 of SpaceLiner (SpaceLiner-7.1), the vehicle should be brought at an altitude of 75 km and then released, undertaking the descent path. In the perspective that the vehicle of SpaceLiner-7.1 could be brought to altitudes higher than 75 km, e.g. 100 km or above and also for a speculative purpose, in this paper the aerodynamic parameters of the SpaceLiner-7.1 vehicle are calculated in the whole transition regime, from continuum low density to free molecular flows. Computer simulations have been carried out by three codes: two DSMC codes, DS3V in the altitude interval 100-250 km for the evaluation of the global aerodynamic coefficients and DS2V at the altitude of 60 km for the evaluation of the heat flux and pressure distributions along the vehicle nose, and the DLR HOTSOSE code for the evaluation of the global aerodynamic coefficients in continuum, hypersonic flow at the altitude of 44.6 km. The effectiveness of the flaps with deflection angle of -35 deg. was evaluated in the above mentioned altitude interval. The vehicle showed longitudinal stability in the whole altitude interval even with no flap. The global bridging formulae verified to be proper for the evaluation of the aerodynamic coefficients in the altitude interval 80-100 km where the computations cannot be fulfilled either by CFD, because of the failure of the classical equations computing the transport coefficients, or by DSMC because of the requirement of very high computer resources both in terms of the core storage (a high number of simulated molecules is needed) and to the very long processing time.

  9. Global dose to man from proposed NNTRP high altitude nuclear tests

    International Nuclear Information System (INIS)

    Peterson, K.R.

    1975-05-01

    Radionuclide measurements from past high altitude nuclear testing have enabled development of a model to estimate surface deposition and doses from 400 kt of fission products injected in winter within the Pacific Test Area at altitudes in excess of 50 km. The largest 30-year average dose to man is about 10 millirem and occurs at 30 0 to 50 0 N latitude. The principal contributor to this dose is external gamma radiation from gross fission products. Individual doses from 90 Sr via the forage-cow-milk pathway and 137 Cs via the pasture-meat pathway are about 1/5 the gross fission product doses. The global 30-year population dose is 3 x 10 7 person-rem, which compares with a 30-year natural background population dose of 1 X 10 10 person-rem. Due in large part to the global distribution of population, over 98 percent of the global person-rem from the proposed high altitude tests is received in the Northern Hemisphere, while about 75 percent of the total population dose occurs within the 30 0 --50 0 N latitude belt. Detonations in summer would decrease the global dose by about a factor of three. (U.S.)

  10. [Arterial hypertension due to altitude].

    Science.gov (United States)

    Domej, Wolfgang; Trapp, Michael; Miggitsch, Eva Maria; Krakher, Tiziana; Riedlbauer, Rita; Roher, Peter; Schwaberger, Günther

    2008-01-01

    The behavior of blood pressure under hypoxic conditions depends on individual factors, altitude and duration of stay at altitude. While most humans are normotensive at higher altitudes, a few will react with moderate hypertension or hypotension. Excessive elevation of arterial blood pressure is not even to be expected below 4,000 m. Rather, several weeks' stay at higher altitude will decrease systolic and diastolic blood pressure at rest as well as during physical exertion. A high-altitude treatment for rehabilitation purposes at moderate altitude may be recommended for patients with cardio-circulatory disorders. Improvements can last several months even after returning to accustomed altitudes. Furthermore, endurance-trained hypertensive patients with pharmacologically controlled arterial blood pressure might be able to participate in mountain treks without additional health risk.

  11. Space environment monitoring by low-altitude operational satellites

    International Nuclear Information System (INIS)

    Kroehl, H.W.

    1982-01-01

    The primary task of the Defense Meteorological Satellite Program (DMSP) is the acquisition of meteorological data in the visual and infrared spectral regions. The Air Weather Service operates two satellites in low-altitude, sun-synchronous, polar orbits at 850 km altitude, 98.7 deg inclination, 101.5 minute period and dawn-dusk or noon-midnight equatorial crossing times. Special DMSP sensors of interest to the space science community are the precipitating electron spectrometer, the terrestrial noise receiver, and the topside ionosphere plasma monitor. Data from low-altitude, meteorological satellites can be used to build empirical models of precipitating electron characteristics of the auroral zone and polar cap. The Tiros-NOAA satellite program complements the DMSP program. The orbital elements are the same as DMSP's, except for the times of equatorial crossing, and the tilt of the orbital plane. The Tiros-NOAA program meets the civilian community's needs for meteorological data as the DMSP program does for the military

  12. Parasympathetic neural activity accounts for the lowering of exercise heart rate at high altitude

    DEFF Research Database (Denmark)

    Boushel, Robert Christopher; Calbet, J A; Rådegran, G

    2001-01-01

    In chronic hypoxia, both heart rate (HR) and cardiac output (Q) are reduced during exercise. The role of parasympathetic neural activity in lowering HR is unresolved, and its influence on Q and oxygen transport at high altitude has never been studied.......In chronic hypoxia, both heart rate (HR) and cardiac output (Q) are reduced during exercise. The role of parasympathetic neural activity in lowering HR is unresolved, and its influence on Q and oxygen transport at high altitude has never been studied....

  13. Molecular mechanisms regulating oxygen transport and consumption in high altitude and hibernating mammals

    DEFF Research Database (Denmark)

    Revsbech, Inge Grønvall

    2016-01-01

    The aim of this thesis is to broaden the knowledge of molecular mechanisms of adjustment in oxygen (O2) uptake, conduction, delivery and consumption in mammals adapted to extreme conditions. For this end, I have worked with animals living at high altitude as an example of environmental hypoxia...... of the repeatedly found adaptive traits in animals living at high altitude and in hibernating mammals during hibernation compared with the active state. Factors that affect O2 affinity of Hb include temperature, H+/CO2 via the Bohr effect as well as Cl- and organic phosphates, in mammals mainly 2...

  14. Rationale and operational plan for a U.S. high-altitude magnetic survey

    Science.gov (United States)

    Hildenbrand, Thomas G.; Acuna, Mario; Bracken, Robert E.; Hardwick, Doug; Hinze, William J.; Keller, Gordon R.; Phillips, Jeff; Roest, Walter

    2002-01-01

    On August 8, 2002, twenty-one scientists from the federal, private and academic sectors met at a workshop in Denver, Co., to discuss the feasibility of collecting magnetic anomaly data on a Canberra aircraft (Figure 1). The need for this 1-day workshop arose because of an exciting and cost-effective opportunity to collect invaluable magnetic anomaly data during a Canberra mission over the U.S. in 2003 and 2004. High Altitude Mapping Missions (HAMM) is currently planning a mission to collect Interferometric Synthetic Aperture Radar (IFSAR) imagery at an altitude of about 15 km and with a flight-line spacing of about 18 km over the conterminous U.S. and Alaska. The additional collection of total and vector magnetic field data would represent a secondary mission objective (i.e., a "piggy-back" magnetometer system). Because HAMM would fund the main flight costs of the mission, the geomagnetic community would obtain invaluable magnetic data at a nominal cost. These unique data would provide new insights on fundamental tectonic and thermal processes and give a new view of the structural and lithologic framework of the crust and possibly the upper mantle. This document highlights: (1) the reasons to conduct this national survey and (2) a preliminary operational plan to collect high-altitude magnetic data of a desired quality and for the expected resources. Although some operational plan issues remain to be resolved, the important conclusions of the workshop are that the Canberra is a very suitable platform to measure the magnetic field and that the planned mission will result in quality high-altitude magnetic data to greatly expand the utility of our national magnetic database.

  15. Short-term cardiorespiratory adaptation to high altitude in children compared with adults.

    Science.gov (United States)

    Kriemler, S; Radtke, T; Bürgi, F; Lambrecht, J; Zehnder, M; Brunner-La Rocca, H P

    2016-02-01

    As short-term cardiorespiratory adaptation to high altitude (HA) exposure has not yet been studied in children, we assessed acute mountain sickness (AMS), hypoxic ventilatory response (HVR) at rest and maximal exercise capacity (CPET) at low altitude (LA) and HA in pre-pubertal children and their fathers. Twenty father-child pairs (11 ± 1 years and 44 ± 4 years) were tested at LA (450 m) and HA (3450 m) at days 1, 2, and 3 after fast ascent (HA1/2/3). HVR was measured at rest and CPET was performed on a cycle ergometer. AMS severity was mild to moderate with no differences between generations. HVR was higher in children than adults at LA and increased at HA similarly in both groups. Peak oxygen uptake (VO2 peak) relative to body weight was similar in children and adults at LA and decreased significantly by 20% in both groups at HA; maximal heart rate did not change at HA in children while it decreased by 16% in adults (P < 0.001). Changes in HVR and VO2 peak from LA to HA were correlated among the biological child-father pairs. In conclusion, cardiorespiratory adaptation to altitude seems to be at least partly hereditary. Even though children and their fathers lose similar fractions of aerobic capacity going to high altitude, the mechanisms might be different. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  16. High altitude pulmonary edema. Report of a case with familiar history

    International Nuclear Information System (INIS)

    Velasquez, Jurg Niederbacher; Rueda Manrique, Adriana L; Sanabria Pico, Carmen E

    1998-01-01

    We report the case of a ten years old child, who presented a high altitude pulmonary edema. His father had the same disorder ten years ago. In addition we review the physiopathology, diagnosis and management of this disease

  17. Amelioration of rCBF and PbtO2 following TBI at high altitude by hyperbaric oxygen pre-conditioning.

    Science.gov (United States)

    Hu, Shengli; Li, Fei; Luo, Haishui; Xia, Yongzhi; Zhang, Jiuquan; Hu, Rong; Cui, Gaoyu; Meng, Hui; Feng, Hua

    2010-03-01

    Hypobaric hypoxia at high altitude can lead to brain damage and pre-conditioning with hyperbaric oxygen (HBO) can reduce ischemic/hypoxic brain injury. This study investigates the effects of high altitude on traumatic brain injury (TBI) and examines the neuroprotection provided by HBO preconditioning against TBI. Rats were randomly divided into four groups: HBO pre-conditioning group (HBOP, n=10), high altitude group (HA, n=10), plain control group (PC, n=10) and plain sham operation group (sham, n=10). All groups were subjected to head trauma by weight drop device except for the sham group. Rats from each group were examined for neurological function, regional cerebral blood flow (rCBF) and brain tissue oxygen pressure (PbtO(2)) and were killed for analysis by transmission electron microscope. The score of neurological deficits in the HA group was highest, followed by the HBOP group and the PC group, respectively. Both rCBF and PbtO(2) were the lowest in the HA group. Brain morphology and structure seen via the transmission electron microscope was diminished in the HA group, while fewer pathological injuries occurred in the HBOP and PC groups. High altitude aggravates TBI significantly and HBO pre-conditioning can attenuate TBI in rats at high altitude by improvement of rCBF and PbtO(2). Pre-treatment with HBO might be beneficial for people traveling to high altitude locations.

  18. Studies on radioactivities of dust samples in the air at high altitudes

    International Nuclear Information System (INIS)

    Kohara, Eri; Muronoi, Naohiro

    2015-01-01

    The radioactivity concentrations of airborne dust samples were studied. The samples had been collected at high altitude by the Japan Air Self-Defense Force from April 2013 to March 2014. The obtained data were used for gross beta radioactivity analysis and gamma nuclide analysis. It is shown that cesium 137 was mainly detected at the 10 km and 3 km altitude of central area of Japan in several samples. Gaseous radioiodine was not detected in all the samples. Radioactive xenon was detected but the concentration did not show significant difference to the background level. (author)

  19. Facile Synthesis of Monodispersed Polysulfide Spheres for Building Structural Colors with High Color Visibility and Broad Viewing Angle.

    Science.gov (United States)

    Li, Feihu; Tang, Bingtao; Wu, Suli; Zhang, Shufen

    2017-01-01

    The synthesis and assembly of monodispersed colloidal spheres are currently the subject of extensive investigation to fabricate artificial structural color materials. However, artificial structural colors from general colloidal crystals still suffer from the low color visibility and strong viewing angle dependence which seriously hinder their practical application in paints, colorimetric sensors, and color displays. Herein, monodispersed polysulfide (PSF) spheres with intrinsic high refractive index (as high as 1.858) and light-absorbing characteristics are designed, synthesized through a facile polycondensation and crosslinking process between sodium disulfide and 1,2,3-trichloropropane. Owing to their high monodispersity, sufficient surface charge, and good dispersion stability, the PSF spheres can be assembled into large-scale and high-quality 3D photonic crystals. More importantly, high structural color visibility and broad viewing angle are easily achieved because the unique features of PSF can remarkably enhance the relative reflectivity and eliminate the disturbance of scattering and background light. The results of this study provide a simple and efficient strategy to create structural colors with high color visibility, which is very important for their practical application. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  20. Glycated haemoglobin (HbA1c ) and fasting plasma glucose relationships in sea-level and high-altitude settings.

    Science.gov (United States)

    Bazo-Alvarez, J C; Quispe, R; Pillay, T D; Bernabé-Ortiz, A; Smeeth, L; Checkley, W; Gilman, R H; Málaga, G; Miranda, J J

    2017-06-01

    Higher haemoglobin levels and differences in glucose metabolism have been reported among high-altitude residents, which may influence the diagnostic performance of HbA 1c . This study explores the relationship between HbA 1c and fasting plasma glucose (FPG) in populations living at sea level and at an altitude of > 3000 m. Data from 3613 Peruvian adults without a known diagnosis of diabetes from sea-level and high-altitude settings were evaluated. Linear, quadratic and cubic regression models were performed adjusting for potential confounders. Receiver operating characteristic (ROC) curves were constructed and concordance between HbA 1c and FPG was assessed using a Kappa index. At sea level and high altitude, means were 13.5 and 16.7 g/dl (P > 0.05) for haemoglobin level; 41 and 40 mmol/mol (5.9% and 5.8%; P < 0.01) for HbA 1c ; and 5.8 and 5.1 mmol/l (105 and 91.3 mg/dl; P < 0.001) for FPG, respectively. The adjusted relationship between HbA 1c and FPG was quadratic at sea level and linear at high altitude. Adjusted models showed that, to predict an HbA 1c value of 48 mmol/mol (6.5%), the corresponding mean FPG values at sea level and high altitude were 6.6 and 14.8 mmol/l (120 and 266 mg/dl), respectively. An HbA 1c cut-off of 48 mmol/mol (6.5%) had a sensitivity for high FPG of 87.3% (95% confidence interval (95% CI) 76.5 to 94.4) at sea level and 40.9% (95% CI 20.7 to 63.6) at high altitude. The relationship between HbA 1c and FPG is less clear at high altitude than at sea level. Caution is warranted when using HbA 1c to diagnose diabetes mellitus in this setting. © 2017 The Authors. Diabetic Medicine published by John Wiley & Sons Ltd on behalf of Diabetes UK.

  1. BETTII: The Balloon Experimental Twin Telescope for Infrared Interferometry (Phase 2a)- High Angular Resolution Astronomy at Far-Infrared Wavelengths

    Science.gov (United States)

    Rinehart, Stephen

    The Balloon Experimental Twin Telescope for Infrared Interferometry (BETTII) is an eight-meter baseline far-infrared interferometer to fly on a high altitude balloon. The combination of the long baseline with a double-Fourier instrument allows BETTII to simultaneously gain both spatial and spectral information; BETTII is designed for spatially-resolved spectroscopy. The unique data obtained with BETTII will be valuable for understanding how stars form within dense clusters, by isolating individual objects that are unresolved by previous space telescopes and my measuring their spectral energy distributions. BETTII will be also used in future flights to understand the processes in the cores of Active Galactic Nuclei. In addition to these scientific goals, BETTII serves as a major step towards achieving the vision of space-based interferometry. BETTII was first funded through the 2010 APRA program; last year, the proposal also fared well in the APRA review, but for programmatic reasons was only awarded one year of funding. With the current funding, we will complete the BETTII experiment and conduct a Commissioning Flight in August/September 2016. The effort proposed includes full analysis of data from the Commissioning Flight, which will help us determine the technical and scientific capabilities of the experiment. It also includes two science flights, one in each 2017 and 2018, with full data analysis being completed in 2019.

  2. THE HIGH A{sub V} Quasar Survey: Reddened Quasi-Stellar Objects selected from optical/near-infrared photometry. II

    Energy Technology Data Exchange (ETDEWEB)

    Krogager, J.-K.; Fynbo, J. P. U.; Vestergaard, M. [Dark Cosmology Centre, Niels Bohr Institute, University of Copenhagen, Juliane Maries Vej 30, DK-2100 Copenhagen Ø (Denmark); Geier, S. [Instituto de Astrofísica de Canarias (IAC), E-38205 La Laguna, Tenerife (Spain); Venemans, B. P. [Max-Planck Institute for Astronomy, Königstuhl 17, D-69117 Heidelberg (Germany); Ledoux, C. [European Southern Observatory, Alonso de Córdova 3107, Vitacura, Casilla 19001, Santiago 19 (Chile); Møller, P. [European Southern Observatory, Karl-Schwarzschildstrasse 2, D-85748 Garching bei München (Germany); Noterdaeme, P. [Institut d’Astrophysique de Paris, CNRS-UPMC, UMR7095, 98bis bd Arago, F-75014 Paris (France); Kangas, T.; Pursimo, T.; Smirnova, O. [Nordic Optical Telescope, Apartado 474, E-38700 Santa Cruz de La Palma (Spain); Saturni, F. G. [Tuorla Observatory, Department of Physics and Astronomy, University of Turku, Väisäläntie 20, 21500 Piikkiö (Finland)

    2015-03-15

    Quasi-stellar objects (QSOs) whose spectral energy distributions (SEDs) are reddened by dust either in their host galaxies or in intervening absorber galaxies are to a large degree missed by optical color selection criteria like the ones used by the Sloan Digital Sky Survey (SDSS). To overcome this bias against red QSOs, we employ a combined optical and near-infrared (near-IR) color selection. In this paper, we present a spectroscopic follow-up campaign of a sample of red candidate QSOs which were selected from the SDSS and the UKIRT Infrared Deep Sky Survey (UKIDSS). The spectroscopic data and SDSS/UKIDSS photometry are supplemented by mid-infrared photometry from the Wide-field Infrared Survey Explorer. In our sample of 159 candidates, 154 (97%) are confirmed to be QSOs. We use a statistical algorithm to identify sightlines with plausible intervening absorption systems and identify nine such cases assuming dust in the absorber similar to Large Magellanic Cloud sightlines. We find absorption systems toward 30 QSOs, 2 of which are consistent with the best-fit absorber redshift from the statistical modeling. Furthermore, we observe a broad range in SED properties of the QSOs as probed by the rest-frame 2 μm flux. We find QSOs with a strong excess as well as QSOs with a large deficit at rest-frame 2 μm relative to a QSO template. Potential solutions to these discrepancies are discussed. Overall, our study demonstrates the high efficiency of the optical/near-IR selection of red QSOs.

  3. A Mid-Infrared Search for Kardashev Civilizations

    Science.gov (United States)

    Sigurdsson, Steinn; Wright, J.; Griffith, R.; Povich, M. S.

    2014-01-01

    We are using the WISE all-sky Source Catalog to search for and put upper limits on the existence of extraterrestrial civilizations with large energy supplies. Any galaxy-spanning (Type III) civilization with an energy supply of more than about one percent of its stellar luminosity will have detectable mid-infrared excess, and nearby (extended) galaxies with civilizations with supplies more than about 80% of their stellar luminosity will be well-distinguished from nearly all natural sources in WISE color-color space. Mid-infrared spectra, far-infrared photometry, and radio emission from CO can all be used to distinguish extraterrestrial mid-infrared radiation from dust.

  4. Glucose intolerance associated with hypoxia in people living at high altitudes in the Tibetan highland.

    Science.gov (United States)

    Okumiya, Kiyohito; Sakamoto, Ryota; Ishimoto, Yasuko; Kimura, Yumi; Fukutomi, Eriko; Ishikawa, Motonao; Suwa, Kuniaki; Imai, Hissei; Chen, Wenling; Kato, Emiko; Nakatsuka, Masahiro; Kasahara, Yoriko; Fujisawa, Michiko; Wada, Taizo; Wang, Hongxin; Dai, Qingxiang; Xu, Huining; Qiao, Haisheng; Ge, Ri-Li; Norboo, Tsering; Tsering, Norboo; Kosaka, Yasuyuki; Nose, Mitsuhiro; Yamaguchi, Takayoshi; Tsukihara, Toshihiro; Ando, Kazuo; Inamura, Tetsuya; Takeda, Shinya; Ishine, Masayuki; Otsuka, Kuniaki; Matsubayashi, Kozo

    2016-02-23

    To clarify the association between glucose intolerance and high altitudes (2900-4800 m) in a hypoxic environment in Tibetan highlanders and to verify the hypothesis that high altitude dwelling increases vulnerability to diabetes mellitus (DM) accelerated by lifestyle change or ageing. Cross-sectional epidemiological study on Tibetan highlanders. We enrolled 1258 participants aged 40-87 years. The rural population comprised farmers in Domkhar (altitude 2900-3800 m) and nomads in Haiyan (3000-3100 m), Ryuho (4400 m) and Changthang (4300-4800 m). Urban area participants were from Leh (3300 m) and Jiegu (3700 m). Participants were classified into six glucose tolerance-based groups: DM, intermediate hyperglycaemia (IHG), normoglycaemia (NG), fasting DM, fasting IHG and fasting NG. Prevalence of glucose intolerance was compared in farmers, nomads and urban dwellers. Effects of dwelling at high altitude or hypoxia on glucose intolerance were analysed with the confounding factors of age, sex, obesity, lipids, haemoglobin, hypertension and lifestyle, using multiple logistic regression. The prevalence of DM (fasting DM)/IHG (fasting IHG) was 8.9% (6.5%)/25.1% (12.7%), respectively, in all participants. This prevalence was higher in urban dwellers (9.5% (7.1%)/28.5% (11.7%)) and in farmers (8.5% (6.1%)/28.5% (18.3%)) compared with nomads (8.2% (5.7%)/15.7% (9.7%)) (p=0.0140/0.0001). Dwelling at high altitude was significantly associated with fasting IHG+fasting DM/fasting DM (ORs for >4500 and 3500-4499 m were 3.59/4.36 and 2.07/1.76 vs intolerance. Socioeconomic factors, hypoxaemia and the effects of altitudes >3500 m play a major role in the high prevalence of glucose intolerance in highlanders. Tibetan highlanders may be vulnerable to glucose intolerance, with polycythaemia as a sign of poor hypoxic adaptation, accelerated by lifestyle change and ageing. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please

  5. Use of Real Time Satellite Infrared and Ocean Color to Produce Ocean Products

    Science.gov (United States)

    Roffer, M. A.; Muller-Karger, F. E.; Westhaver, D.; Gawlikowski, G.; Upton, M.; Hall, C.

    2014-12-01

    Real-time data products derived from infrared and ocean color satellites are useful for several types of users around the world. Highly relevant applications include recreational and commercial fisheries, commercial towing vessel and other maritime and navigation operations, and other scientific and applied marine research. Uses of the data include developing sampling strategies for research programs, tracking of water masses and ocean fronts, optimizing ship routes, evaluating water quality conditions (coastal, estuarine, oceanic), and developing fisheries and essential fish habitat indices. Important considerations for users are data access and delivery mechanisms, and data formats. At this time, the data are being generated in formats increasingly available on mobile computing platforms, and are delivered through popular interfaces including social media (Facebook, Linkedin, Twitter and others), Google Earth and other online Geographical Information Systems, or are simply distributed via subscription by email. We review 30 years of applications and describe how we develop customized products and delivery mechanisms working directly with users. We review benefits and issues of access to government databases (NOAA, NASA, ESA), standard data products, and the conversion to tailored products for our users. We discuss advantages of different product formats and of the platforms used to display and to manipulate the data.

  6. On the High Altitude Platform (HAP W-CDMA System Capacity

    Directory of Open Access Journals (Sweden)

    L. de Haro-Ariet

    2004-06-01

    Full Text Available The performance of a downlink power control model, based on a n-thpower distance law, is evaluated for high altitude platform station(HAPS W-CDMA systems. The downlink capacity using this model iscompared with the uplink capacity. It is shown that the uplink capacityis higher than the downlink capacity.

  7. Oxidative DNA damage and repair in skeletal muscle of humans exposed to high-altitude hypoxia

    International Nuclear Information System (INIS)

    Lundby, Carsten; Pilegaard, Henriette; Hall, Gerrit van; Sander, Mikael; Calbet, Jose; Loft, Steffen; Moeller, Peter

    2003-01-01

    Recent research suggests that high-altitude hypoxia may serve as a model for prolonged oxidative stress in healthy humans. In this study, we investigated the consequences of prolonged high-altitude hypoxia on the basal level of oxidative damage to nuclear DNA in muscle cells, a major oxygen-consuming tissue. Muscle biopsies from seven healthy humans were obtained at sea level and after 2 and 8 weeks of hypoxia at 4100 m.a.s.l. We found increased levels of strand breaks and endonuclease III-sensitive sites after 2 weeks of hypoxia, whereas oxidative DNA damage detected by formamidopyrimidine DNA glycosylase (FPG) protein was unaltered. The expression of 8-oxoguanine DNA glycosylase 1 (OGG1), determined by quantitative RT-PCR of mRNA levels did not significantly change during high-altitude hypoxia, although the data could not exclude a minor upregulation. The expression of heme oxygenase-1 (HO-1) was unaltered by prolonged hypoxia, in accordance with the notion that HO-1 is an acute stress response protein. In conclusion, our data indicate high-altitude hypoxia may serve as a good model for oxidative stress and that antioxidant genes are not upregulated in muscle tissue by prolonged hypoxia despite increased generation of oxidative DNA damage

  8. Atmospheric Sampling of Aerosols to Stratospheric Altitudes using High Altitude Balloons

    Science.gov (United States)

    Jerde, E. A.; Thomas, E.

    2010-12-01

    Although carbon dioxide represents a long-lived atmospheric component relevant to global climate change, it is also understood that many additional contributors influence the overall climate of Earth. Among these, short-lived components are more difficult to incorporate into models due to uncertainties in the abundances of these both spatially and temporally. Possibly the most significant of these short-lived components falls under the heading of “black carbon” (BC). There are numerous overlapping definitions of BC, but it is basically carbonaceous in nature and light absorbing. Due to its potential as a climate forcer, an understanding of the BC population in the atmosphere is critical for modeling of radiative forcing. Prior measurements of atmospheric BC generally consist of airplane- and ground-based sampling, typically below 5000 m and restricted in time and space. Given that BC has a residence time on the order of days, short-term variability is easily missed. Further, since the radiative forcing is a result of BC distributed through the entire atmospheric column, aircraft sampling is by definition incomplete. We are in the process of planning a more comprehensive sampling of the atmosphere for BC using high-altitude balloons. Balloon-borne sampling is a highly reliable means to sample air through the entire troposphere and into the lower stratosphere. Our system will incorporate a balloon and a flight train of two modules. One module will house an atmospheric sampler. This sampler will be single-stage (samples all particle sizes together), and will place particles directly on an SEM sample stub for analysis. The nozzle depositing the sample will be offset from the center of the stub, placing the aerosol particles toward the edge. At various altitudes, the stub will be rotated 45 degrees, providing 6-8 sample “cuts” of particle populations through the atmospheric column. The flights will reach approximately 27 km altitude, above which the balloons

  9. Near-infrared photometry of bright elliptical galaxies

    NARCIS (Netherlands)

    Peletier, R. F.; Valentijn, E. A.; Jameson, R. F.

    High-quality visual-infrared color profiles have been determined for elliptical galaxies for the first time. Surface photometry in J and K is presented for 12 bright elliptical galaxies, and the results have been combined with CCD data in visual passbands. It is shown that the galaxies become bluer

  10. Cardiovascular Effects of Altitude on Performance Athletes.

    Science.gov (United States)

    Shah, Ankit B; Coplan, Neil

    Altitude plays an important role in cardiovascular performance and training for athletes. Whether it is mountaineers, skiers, or sea-level athletes trying to gain an edge by training or living at increased altitude, there are many potential benefits and harms of such endeavors. Echocardiographic studies done on athletes at increased altitude have shown evidence for right ventricular dysfunction and pulmonary hypertension, but no change in left ventricular ejection fraction. In addition, 10% of athletes are susceptible to pulmonary hypertension and high-altitude pulmonary edema. Some studies suggest that echocardiography may be able to identify athletes susceptible to high-altitude pulmonary edema prior to competing or training at increased altitudes. Further research is needed on the long-term effects of altitude training, as repeated, transient episodes of pulmonary hypertension and right ventricular dysfunction may have long-term implications. Current literature suggests that performance athletes are not at higher risk for ventricular arrhythmias when training or competing at increased altitudes. For sea-level athletes, the optimal strategy for attaining the benefits while minimizing the harms of altitude training still needs to be clarified, although-for now-the "live high, train low" approach appears to have the most rationale.

  11. Anti-hypotensive treatment and endothelin blockade synergistically antagonize exercise fatigue in rats under simulated high altitude.

    Directory of Open Access Journals (Sweden)

    Daniel Radiloff

    Full Text Available Rapid ascent to high altitude causes illness and fatigue, and there is a demand for effective acute treatments to alleviate such effects. We hypothesized that increased oxygen delivery to the tissue using a combination of a hypertensive agent and an endothelin receptor A antagonist drugs would limit exercise-induced fatigue at simulated high altitude. Our data showed that the combination of 0.1 mg/kg ambrisentan with either 20 mg/kg ephedrine or 10 mg/kg methylphenidate significantly improved exercise duration in rats at simulated altitude of 4,267 m, whereas the individual compounds did not. In normoxic, anesthetized rats, ephedrine alone and in combination with ambrisentan increased heart rate, peripheral blood flow, carotid and pulmonary arterial pressures, breathing rate, and vastus lateralis muscle oxygenation, but under inspired hypoxia, only the combination treatment significantly enhanced muscle oxygenation. Our results suggest that sympathomimetic agents combined with endothelin-A receptor blockers offset altitude-induced fatigue in rats by synergistically increasing the delivery rate of oxygen to hypoxic muscle by concomitantly augmenting perfusion pressure and improving capillary conductance in the skeletal muscle. Our findings might therefore serve as a basis to develop an effective treatment to prevent high-altitude illness and fatigue in humans.

  12. The Effect of Sex on Heart Rate Variability at High Altitude.

    Science.gov (United States)

    Boos, Christopher John; Vincent, Emma; Mellor, Adrian; O'Hara, John; Newman, Caroline; Cruttenden, Richard; Scott, Phylip; Cooke, Mark; Matu, Jamie; Woods, David Richard

    2017-12-01

    There is evidence suggesting that high altitude (HA) exposure leads to a fall in heart rate variability (HRV) that is linked to the development of acute mountain sickness (AMS). The effects of sex on changes in HRV at HA and its relationship to AMS are unknown. HRV (5-min single-lead ECG) was measured in 63 healthy adults (41 men and 22 women) 18-56 yr of age at sea level (SL) and during a HA trek at 3619, 4600, and 5140 m, respectively. The main effects of altitude (SL, 3619 m, 4600 m, and 5140 m) and sex (men vs women) and their potential interaction were assessed using a factorial repeated-measures ANOVA. Logistic regression analyses were performed to assess the ability of HRV to predict AMS. Men and women were of similar age (31.2 ± 9.3 vs 31.7 ± 7.5 yr), ethnicity, and body and mass index. There was main effect for altitude on heart rate, SD of normal-to-normal (NN) intervals (SDNN), root mean square of successive differences (RMSSD), number of pairs of successive NN differing by >50 ms (NN50), NN50/total number of NN, very low-frequency power, low-frequency (LF) power, high-frequency (HF) power, and total power (TP). The most consistent effect on post hoc analysis was reduction in these HRV measures between 3619 and 5140 m at HA. Heart rate was significantly lower and SDNN, RMSSD, LF power, HF power, and TP were higher in men compared with women at HA. There was no interaction between sex and altitude for any of the HRV indices measured. HRV was not predictive of AMS development. Increasing HA leads to a reduction in HRV. Significant differences between men and women emerge at HA. HRV was not predictive of AMS.

  13. THE INFRARED PROPERTIES OF EMBEDDED SUPER STAR CLUSTERS: PREDICTIONS FROM THREE-DIMENSIONAL RADIATIVE TRANSFER MODELS

    International Nuclear Information System (INIS)

    Whelan, David G.; Johnson, Kelsey E.; Indebetouw, Remy; Whitney, Barbara A.; Wood, Kenneth

    2011-01-01

    With high-resolution infrared data becoming available that can probe the formation of high-mass stellar clusters for the first time, appropriate models that make testable predictions of these objects are necessary. We utilize a three-dimensional radiative transfer code, including a hierarchically clumped dusty envelope, to study the earliest stages of super star cluster (SSC) evolution. We explore a range of parameter space in geometric sequences that mimic the hypothesized evolution of an embedded SSC. The inclusion of a hierarchically clumped medium can make the envelope porous, in accordance with previous models and supporting observational evidence. The infrared luminosity inferred from observations can differ by a factor of two from the true value in the clumpiest envelopes depending on the viewing angle. The infrared spectral energy distribution also varies with viewing angle for clumpy envelopes, creating a range in possible observable infrared colors and magnitudes, silicate feature depths, and dust continua. General observable features of cluster evolution differ between envelopes that are relatively opaque or transparent to mid-infrared photons. For optically thick envelopes, evolution is marked by a gradual decline of the 9.8 μm silicate absorption feature depth and a corresponding increase in the visual/ultraviolet flux. For the optically thin envelopes, clusters typically begin with a strong hot dust component and silicates in emission, and these features gradually fade until the mid-infrared polycyclic aromatic hydrocarbon features are predominant. For the models with a smooth dust distribution, the Spitzer MIPS or Herschel PACS [70]-[160] color is a good probe of the stellar mass relative to the total mass or star formation efficiency (SFE). Likewise, the IRAC/MIPS [3.6]-[24] color can be used to constrain the R in and R out values of the envelope. However, clumpiness confuses the general trends seen in the smooth dust distribution models, making it

  14. Effect of solar radiation (UV and visible) at high altitude on CAM-cycling and phenolic compound biosynthesis in Sedum album

    International Nuclear Information System (INIS)

    Bachereau, F.; Marigo, G.; Asta, J.

    1998-01-01

    The field experiment was carried out in order to compare the response of a CAM plant, Sedum album L., to solar radiation at a high altitude (2 100 m) with that at a low altitude location with respect to CAM and phenolic content. Treatment sites included (1) sun-exposed, low altitude, (2) sun-exposed, high altitude with different light treatments, including UV-B and UV-B + A screening, and (3) shade at high altitude. After a 70-day treatment period, CAM-cycling and phenolic compound content were analysed, and high altitude treatments were compared to the low altitude control. The sun-exposed low altitude control was characterized by CAM-cycling and a low phenolic compound content during the experiment. In plants transplanted to the high altitude, only the shaded group maintained a CAM-cycling and a phenolic compound content similar to those of the sun-exposed low altitude control. Samples under UV-B and UV-B + A filters showed similar responses, suggesting the absence of a specific UV-A radiation effect. The screening of UV-B or UV-B + A radiation allowed plants to partially maintain a CAM-cycling and induced a decrease in phenolic compound content. These responses under UV filters were, however, intermediate between those observed in sun-exposed and shaded groups. These results demonstrate a specific effect of radiation from both visible (400–800 nm) and UV-B (280–320 nm) bands on both CAM-cycling and phenolic biosynthesis in S. album L. plants. These light-dependent effects are discussed on a physiological basis and a possible interaction between CAM-cycling and phenolic metabolism is suggested. (author)

  15. 4 Vesta in Color: High Resolution Mapping from Dawn Framing Camera Images

    Science.gov (United States)

    Reddy, V.; LeCorre, L.; Nathues, A.; Sierks, H.; Christensen, U.; Hoffmann, M.; Schroeder, S. E.; Vincent, J. B.; McSween, H. Y.; Denevi, B. W.; hide

    2011-01-01

    Rotational surface variations on asteroid 4 Vesta have been known from ground-based and HST observations, and they have been interpreted as evidence of compositional diversity. NASA s Dawn mission entered orbit around Vesta on July 16, 2011 for a year-long global characterization. The framing cameras (FC) onboard the Dawn spacecraft will image the asteroid in one clear (broad) and seven narrow band filters covering the wavelength range between 0.4-1.0 microns. We present color mapping results from the Dawn FC observations of Vesta obtained during Survey orbit (approx.3000 km) and High-Altitude Mapping Orbit (HAMO) (approx.950 km). Our aim is to create global color maps of Vesta using multi spectral FC images to identify the spatial extent of compositional units and link them with other available data sets to extract the basic mineralogy. While the VIR spectrometer onboard Dawn has higher spectral resolution (864 channels) allowing precise mineralogical assessment of Vesta s surface, the FC has three times higher spatial resolution in any given orbital phase. In an effort to extract maximum information from FC data we have developed algorithms using laboratory spectra of pyroxenes and HED meteorites to derive parameters associated with the 1-micron absorption band wing. These parameters will help map the global distribution of compositionally related units on Vesta s surface. Interpretation of these units will involve the integration of FC and VIR data.

  16. [Splenic infarction at high altitude, Huaraz-Peru (3,100 masl)].

    Science.gov (United States)

    López de Guimaraes, Douglas; Menacho López, Julio; Villanueva Palacios, Jovita; Mosquera Vásquez, Vitaliano

    2009-01-01

    We report three cases of splenic infarction in healthy men for the first time that amounted to high altitudes, observed in the hospital "Victor Ramos Guardia" Huaraz (3100 m). Case 1 (1995) of 55 years, born in Cuba, from Lima, caucasian suddenly presented acute abdominal pain in epigastrium, distension, nausea and vomiting, was laparotomized for acute abdomen and surgical pathology revealed thrombosis with splenic infarction splenic artery and vein. During follow-up in Lima, hemoglobin electrophoresis showed that it was heterozygous carrier of the sickle trait (Hb A: 57% Hb S: 38.5%). Case 2 (1998) of 23 years, born in Cuba, from Lima, Black said acute abdominal pain in left hypochondrium, shortness of breath and chest pain, clinical examination and radiography of the abdomen showed the spleen volume increased. Case 3 (2006) of 17 years, natural and from Lima, mestizo, who came on tour promotion, acute abdominal pain referred onset in the epigastrium and left hypochondrium, headache, increase heat, nausea and vomiting, pharyngitis was found acute and painful, and spleen increased in size by clinical and x-ray of abdomen simple stand. None had no history of hemoglobinopathy and anemia. In general, medical management was supportive and cases 2 and 3 are recommended hemoglobin electrophoresis. We conclude that we must think of splenic infarction associated with height in any healthy person who is first at high altitude (> 3000m) and having a sudden acute abdominal pain in epigastrium and / or left hypochondrium, pain and palpable spleen and radiological study compatible with image. In this case is indicated by hemoglobin electrophoresis to determine whether there is an individual heterozygous carrier of the sickle trait. splenic infarction, high altitude, sickle trait, Huaraz.

  17. Fit for high altitude: are hypoxic challenge tests useful?

    Directory of Open Access Journals (Sweden)

    Matthys Heinrich

    2011-02-01

    Full Text Available Abstract Altitude travel results in acute variations of barometric pressure, which induce different degrees of hypoxia, changing the gas contents in body tissues and cavities. Non ventilated air containing cavities may induce barotraumas of the lung (pneumothorax, sinuses and middle ear, with pain, vertigo and hearing loss. Commercial air planes keep their cabin pressure at an equivalent altitude of about 2,500 m. This leads to an increased respiratory drive which may also result in symptoms of emotional hyperventilation. In patients with preexisting respiratory pathology due to lung, cardiovascular, pleural, thoracic neuromuscular or obesity-related diseases (i.e. obstructive sleep apnea an additional hypoxic stress may induce respiratory pump and/or heart failure. Clinical pre-altitude assessment must be disease-specific and it includes spirometry, pulsoximetry, ECG, pulmonary and systemic hypertension assessment. In patients with abnormal values we need, in addition, measurements of hemoglobin, pH, base excess, PaO2, and PaCO2 to evaluate whether O2- and CO2-transport is sufficient. Instead of the hypoxia altitude simulation test (HAST, which is not without danger for patients with respiratory insufficiency, we prefer primarily a hyperoxic challenge. The supplementation of normobaric O2 gives us information on the acute reversibility of the arterial hypoxemia and the reduction of ventilation and pulmonary hypertension, as well as about the efficiency of the additional O2-flow needed during altitude exposure. For difficult judgements the performance of the test in a hypobaric chamber with and without supplemental O2-breathing remains the gold standard. The increasing numbers of drugs to treat acute pulmonary hypertension due to altitude exposure (acetazolamide, dexamethasone, nifedipine, sildenafil or to other etiologies (anticoagulants, prostanoids, phosphodiesterase-5-inhibitors, endothelin receptor antagonists including mechanical aids to

  18. Fit for high altitude: are hypoxic challenge tests useful?

    Science.gov (United States)

    Matthys, Heinrich

    2011-02-28

    Altitude travel results in acute variations of barometric pressure, which induce different degrees of hypoxia, changing the gas contents in body tissues and cavities. Non ventilated air containing cavities may induce barotraumas of the lung (pneumothorax), sinuses and middle ear, with pain, vertigo and hearing loss. Commercial air planes keep their cabin pressure at an equivalent altitude of about 2,500 m. This leads to an increased respiratory drive which may also result in symptoms of emotional hyperventilation. In patients with preexisting respiratory pathology due to lung, cardiovascular, pleural, thoracic neuromuscular or obesity-related diseases (i.e. obstructive sleep apnea) an additional hypoxic stress may induce respiratory pump and/or heart failure. Clinical pre-altitude assessment must be disease-specific and it includes spirometry, pulsoximetry, ECG, pulmonary and systemic hypertension assessment. In patients with abnormal values we need, in addition, measurements of hemoglobin, pH, base excess, PaO2, and PaCO2 to evaluate whether O2- and CO2-transport is sufficient.Instead of the hypoxia altitude simulation test (HAST), which is not without danger for patients with respiratory insufficiency, we prefer primarily a hyperoxic challenge. The supplementation of normobaric O2 gives us information on the acute reversibility of the arterial hypoxemia and the reduction of ventilation and pulmonary hypertension, as well as about the efficiency of the additional O2-flow needed during altitude exposure. For difficult judgements the performance of the test in a hypobaric chamber with and without supplemental O2-breathing remains the gold standard. The increasing numbers of drugs to treat acute pulmonary hypertension due to altitude exposure (acetazolamide, dexamethasone, nifedipine, sildenafil) or to other etiologies (anticoagulants, prostanoids, phosphodiesterase-5-inhibitors, endothelin receptor antagonists) including mechanical aids to reduce periodical or

  19. Increasing alpine transit traffic through Switzerland will considerably enhance high altitude alpine pollutant levels

    Energy Technology Data Exchange (ETDEWEB)

    Prevot, A S.H.; Dommen, J; Furger, M; Graber, W K [Paul Scherrer Inst. (PSI), Villigen (Switzerland)

    1999-08-01

    Within the EU-Project VOTALP (Vertical Ozone Transports in the Alps), we have shown that deep alpine valleys like the Mesolcina Valley very efficiently transport air out of the polluted valley up to altitudes between 2000 and near 4000 m asl (above sea level). Pollutants emitted in these valleys are very efficiently transported up to high altitudes. (author) 2 figs., 1 tab., 2 refs.

  20. The effect of chronic erythrocytic polycythemia and high altitude upon plasma and blood volumes.

    Science.gov (United States)

    Burton, R. R.; Smith, A. H.

    1972-01-01

    Comparison of two kinds of physiological chronic erythrocytic polycythemias in order to differentiate the specific effect of erythrocytic polycythemia from the general effects of high altitude upon the plasma volume. The two kinds were produced hormonally in female chickens, at sea level, or by protracted high-altitude exposures. It appears that the vascular system of the body may account for an increase in red blood cell mass either by reduction in plasma volume, or by no change in plasma volume, resulting in differential changes in total blood volumes.

  1. Novel Heterongineered Detectors for Multi-Color Infrared Sensing

    Science.gov (United States)

    2012-01-30

    a) Sequential but collocated two-color detection capabilities of type II InAsGaSb SLS detector based on an nBn design and (b) Simultaneous and...captions: Figure 1. Heterostructure Schematic of (a) PbIbN Design, (b) Dual Color Detector Design with flat band energy lineups . Figure 2. (a) Spectral

  2. Unmanned Aerial Vehicles: Progress Toward Meeting High Altitude Endurance Aircraft Price Goals

    National Research Council Canada - National Science Library

    1998-01-01

    ...) High Altitude Endurance (HAE) Unmanned Aerial Vehicle (UAV) program to determine whether the average flyaway cost for the Global Hawk and DarkStar HAE alr vehicles will be within DOD's cost goal...

  3. IRAS Colors of the Pleiades

    Science.gov (United States)

    Carey, Sean J.; Shipman, R. F.; Clark, F. O.

    1996-01-01

    We present large scale images of the infrared emission of the region around the Pleiades using the ISSA data product from the IRAS mission. Residual Zodiacal background and a discontinuity in the image due to the scanning strategy of the satellite necessitated special background subtraction methods. The 60/100 color image clearly shows the heating of the ambient interstellar medium by the cluster. The 12/100 and 25/100 images peak on the cluster as expected for exposure of small dust grains to an enhanced UV radiation field; however, the 25/100 color declines to below the average interstellar value at the periphery of the cluster. Potential causes of the color deficit are discussed. A new method of identifying dense molecular material through infrared emission properties is presented. The difference between the 100 micron flux density and the 60 micron flux density scaled by the average interstellar 60/100 color ratio (Delta I(sub 100) is a sensitive diagnostic of material with embedded heating sources (Delta I(sub 100) less than 0) and cold, dense cores (Delta I(sub 100) greater than 0). The dense cores of the Taurus cloud complex as well as Lynds 1457 are clearly identified by this method, while the IR bright but diffuse Pleiades molecular cloud is virtually indistinguishable from the nearby infrared cirrus.

  4. RED EYES ON WOLF-RAYET STARS: 60 NEW DISCOVERIES VIA INFRARED COLOR SELECTION

    International Nuclear Information System (INIS)

    Mauerhan, Jon C.; Van Dyk, Schuyler D.; Morris, Patrick W.

    2011-01-01

    We have spectroscopically identified 60 Galactic Wolf-Rayet (WR) stars, including 38 nitrogen types (WN) and 22 carbon types (WC). Using photometry from the Spitzer/GLIMPSE and Two Micron All Sky Survey databases, the new WRs were selected via a method we have established that exploits their unique infrared colors, which is mainly the result of excess radiation generated by free-free scattering within their dense ionized winds. The selection criterion has been refined since the last report, resulting in a WR detection rate of ∼20% in spectroscopic follow-up of candidates that comprise a broad color space defined by the color distribution of all known WRs having B > 14 mag. However, there are smaller regions within this color space that yield WRs at a rate of >50% in spectroscopic follow-up. Candidates that are not WRs are mainly Be stars, which is possibly attributable to the physical similarities between the free-free emission parameters of Be disks and WR winds. As an additional selection experiment, the list of WR candidates was cross-correlated with archival X-ray point-source catalogs, which increases the WR detection rate of the broad color space to ∼40%; 10 new WR X-ray sources have been found in addition to a previously unrecognized X-ray counterpart to a known WR. The extinction values, distances, and Galactocentric radii of all new WRs are calculated using the method of spectroscopic parallax. Although the majority of the new WRs have no obvious association with stellar clusters, two WC8 stars reside in a previously unknown massive-star cluster, in which five OB supergiants were also identified. The new system lies at an estimated distance of ∼6.1 kpc, near the intersection of the Scutum-Centaurus Arm with the Galaxy's bar. In addition, two WC and four WN stars, all but one of which are X-ray sources, were identified in association with the stellar clusters Danks 1 and 2. A WN9 star has also been associated with the cluster [DBS2003] 179. This work

  5. Museum lighting for golden artifacts, with low correlated color temperature, high color uniformity and high color rendering index, using diffusing color mixing of red, cyan, and white-light-emitting diodes

    DEFF Research Database (Denmark)

    Thorseth, Anders; Corell, Dennis Dan; Poulsen, Peter Behrensdorff

    2012-01-01

    at the Royal Danish Collection at Rosenborg Castle. Color mixing of red, cyan, and white LEDs was employed to achieve the spectral power distribution needed for the required CCT and a CRI above 90. Color uniformity is achieved by the use of a highly diffusing reflector. The system has shown energy saving above......Museum lighting presents challenges mainly due to the demand for precise color rendering and the damaging effects of radiation. Golden objects must normally be illuminated by the non-standard CCT of 2200 K. An LED system that conforms to these requirements has been developed and implemented...

  6. A statistical study of high-altitude electric fields measured on the Viking satellite

    International Nuclear Information System (INIS)

    Lindqvist, P.A.; Marklund, G.T.

    1990-01-01

    Characteristics of high-altitude data from the Viking electric field instrument are presented in a statistical study based on 109 Viking orbits. The study is focused in particular on the signatures of and relationships between various parameters measured by the electric field instrument, such as the parallel and transverse (to B) components of the electric field instrument, such as electric field variability. A major goal of the Viking mission was to investigate the occurrence and properties of parallel electric fields and their role in the auroral acceleration process. The results in this paper on the altitude distribution of the electric field variability confirm earlier findings on the distribution of small-scale electric fields and indicate the presence of parallel fields up to about 11,000 km altitude. The directly measured parallel electric field is also investigated in some detail. It is in general directed upward with an average value of 1 mV/m, but depends on, for example, altitude and plasma density. Possible sources of error in the measurement of the parallel field are also considered and accounted for

  7. Optic neuropathy following an altitude exposure.

    Science.gov (United States)

    Steigleman, Allan; Butler, Frank; Chhoeu, Austin; O'Malley, Timothy; Bower, Eric; Giebner, Stephen

    2003-09-01

    This case report describes a 20-yr-old man who presented with retro-orbital pain and blurred vision in his left eye 3 wk after an altitude exposure in a hypobaric chamber. He was found to have significant deficits in color vision and visual fields consistent with an optic neuropathy in his left eye. The patient was diagnosed with decompression sickness and treated with hyperbaric oxygen with a U.S. Navy Treatment Table VI. All signs and symptoms resolved with a single hyperbaric oxygen treatment but recurred. A head MRI revealed a left frontoethmoid sinus opacity. A concomitant sinusitis was diagnosed. The patient had full resolution of symptoms after a total of four hyperbaric oxygen treatments and antibiotic therapy at 6-wk follow-up. Although a para-infectious etiology for this patient's optic neuropathy cannot be excluded, his history of altitude exposure and significant, rapid response to hyperbaric oxygen treatment strongly implies decompression sickness in this case.

  8. Delineation of thermal effluents discharged into tropical waters around Puerto Rico by aerial infrared scanning

    International Nuclear Information System (INIS)

    Wood, E.D.

    1975-01-01

    Aerial infrared scanning offers a versatile tool with which to monitor thermal discharges and a rapid method of detecting extraneous discharges, whose temperatures differ from the ambient waters. Knowledge of the extent and distribution of thermal effluents is necessary to assist in determining the effects of the added heat upon biota of the region. An AGA Model 680 Thermovision infrared scanner with a 45 0 lens was mounted in a Cessna 182, and flown at altitudes of 600 to 2000 m during night and twilight hours. The detector was InSb, cooled with liquid nitrogen and sensitive to the range 2 to 5.6 μm. The picture was originally displayed on a color monitor which assigned ten arbitrary colors to shades of gray on the control unit. Isotherms have been assigned using coincidental surface measurements made with a thermometer, read to the nearest 0.1 0 C. The data were then recorded on film. Ranges were set at 2 0 C and 5 0 C, common sensitivities were 0.2 0 C and 0.5 0 C, respectively. More recently, the data have been recorded on magnetic tapes with a Sabre III instrumentation tape recorder. Observed data have been compared to predictions made using the Pritchard Plume Model. Anomalies can be explained by boundary, wind, and tidal effects. (U.S.)

  9. Evaluation of color encodings for high dynamic range pixels

    Science.gov (United States)

    Boitard, Ronan; Mantiuk, Rafal K.; Pouli, Tania

    2015-03-01

    Traditional Low Dynamic Range (LDR) color spaces encode a small fraction of the visible color gamut, which does not encompass the range of colors produced on upcoming High Dynamic Range (HDR) displays. Future imaging systems will require encoding much wider color gamut and luminance range. Such wide color gamut can be represented using floating point HDR pixel values but those are inefficient to encode. They also lack perceptual uniformity of the luminance and color distribution, which is provided (in approximation) by most LDR color spaces. Therefore, there is a need to devise an efficient, perceptually uniform and integer valued representation for high dynamic range pixel values. In this paper we evaluate several methods for encoding colour HDR pixel values, in particular for use in image and video compression. Unlike other studies we test both luminance and color difference encoding in a rigorous 4AFC threshold experiments to determine the minimum bit-depth required. Results show that the Perceptual Quantizer (PQ) encoding provides the best perceptual uniformity in the considered luminance range, however the gain in bit-depth is rather modest. More significant difference can be observed between color difference encoding schemes, from which YDuDv encoding seems to be the most efficient.

  10. Mammals of the high altitudes of western Arunachal Pradesh, eastern Himalaya: an assessment of threats and conservation needs

    NARCIS (Netherlands)

    Mishra, C.; Madhusudan, M.D.; Datta, A.

    2006-01-01

    he high altitudes of Arunachal Pradesh, India, located in the Eastern Himalaya biodiversity hotspot, remain zoologically unexplored and unprotected. We report results of recent mammal surveys in the high altitude habitats of western Arunachal Pradesh. A total of 35 mammal species (including 12

  11. Flight simulation program for high altitude long endurance unmanned vehicle; Kokodo mujinki no hiko simulation program

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, H.; Hashidate, M. [National Aerospace Laboratory, Tokyo (Japan)

    1995-11-01

    An altitude of about 20 km has the atmospheric density too dilute for common aircraft, and the air resistance too great for satellites. Attention has been drawn in recent years on a high-altitude long-endurance unmanned vehicle that flies at this altitude for a long period of time to serve as a wave relaying base and perform traffic control. Therefore, a development was made on a flight simulation program to evaluate and discuss the guidance and control laws for the high-altitude unmanned vehicle. Equations of motion were derived for three-dimensional six freedom and three-dimensional three freedom. Aerodynamic characteristics of an unmanned vehicle having a Rectenna wing were estimated, and formulation was made according to the past research results on data of winds that the unmanned vehicle is anticipated to encounter at an altitude of 20 km. Noticing the inside of a horizontal plane, a proposal was given on a guidance law that follows a given path. A flight simulation was carried out to have attained a prospect that the unmanned vehicle may be enclosed in a limited space even if the vehicle is encountered with a relatively strong wind. 18 refs., 20 figs., 1 tab.

  12. Nike Black Brant V high altitude dynamic instability characteristics

    Science.gov (United States)

    Montag, W. H.; Walker, L. L., Jr.

    1979-01-01

    Flight experience on the Nike Black Brant V has demonstrated the existence of plume induced flow separation over the fins and aft body of the Black Brant V motor. Modelling of the forces associated with this phenomenon as well as analysis of the resultant vehicle coning motion and its effect on the velocity vector heading are presented. A summary of Nike Black Brant V flight experience with high altitude dynamic instability is included.

  13. High-Altitude Platforms — Present Situation and Technology Trends

    OpenAIRE

    d’Oliveira, Flavio Araripe; Melo, Francisco Cristovão Lourenço de; Devezas, Tessaleno Campos

    2016-01-01

    ABSTRACT High-altitude platforms (HAPs) are aircraft, usually unmanned airships or airplanes positioned above 20 km, in the stratosphere, in order to compose a telecommunications network or perform remote sensing. In the 1990 and 2000 decades, several projects were launched, but very few had continued. In 2014, 2 major Internet companies (Google and Facebook) announced investments in new HAP projects to provide Internet access in regions without communication infrastructure (terrestrial or sa...

  14. Long-Term Intermittent Work at High Altitude: Right Heart Functional and Morphological Status and Associated Cardiometabolic Factors.

    Science.gov (United States)

    Brito, Julio; Siques, Patricia; López, Rosario; Romero, Raul; León-Velarde, Fabiola; Flores, Karen; Lüneburg, Nicole; Hannemann, Juliane; Böger, Rainer H

    2018-01-01

    Background: Living at high altitude or with chronic hypoxia implies functional and morphological changes in the right ventricle and pulmonary vasculature with a 10% prevalence of high-altitude pulmonary hypertension (HAPH). The implications of working intermittently (day shifts) at high altitude (hypobaric hypoxia) over the long term are still not well-defined. The aim of this study was to evaluate the right cardiac circuit status along with potentially contributory metabolic variables and distinctive responses after long exposure to the latter condition. Methods: A cross-sectional study of 120 healthy miners working at an altitude of 4,400-4,800 m for over 5 years in 7-day commuting shifts was designed. Echocardiography was performed on day 2 at sea level. Additionally, biomedical and biochemical variables, Lake Louise scores (LLSs), sleep disturbances and physiological variables were measured at altitude and at sea level. Results: The population was 41.8 ± 0.7 years old, with an average of 14 ± 0.5 (range 5-29) years spent at altitude. Most subjects still suffered from mild to moderate symptoms of acute mountain sickness (mild was an LLS of 3-5 points, including cephalea; moderate was LLS of 6-10 points) (38.3%) at the end of day 1 of the shift. Echocardiography showed a 23% mean pulmonary artery pressure (mPAP) >25 mmHg, 9% HAPH (≥30 mmHg), 85% mild increase in right ventricle wall thickness (≥5 mm), 64% mild right ventricle dilation, low pulmonary vascular resistance (PVR) and fairly good ventricle performance. Asymmetric dimethylarginine (ADMA) (OR 8.84 (1.18-66.39); p Working intermittently at high altitude involves a distinctive pattern. The most relevant and novel characteristics are a greater prevalence of elevated mPAP and HAPH than previously reported at chronic intermittent hypobaric hypoxia (CIHH), which is accompanied by subsequent morphological characteristics. These findings are associated with cardiometabolic factors (insulin and ADMA

  15. Propagation and Breaking at High Altitudes of Gravity Waves Excited by Tropospheric Forcing

    Science.gov (United States)

    Prusa, Joseph M.; Smolarkiewicz, Piotr K.; Garcia, Rolando R.

    1996-01-01

    An anelastic approximation is used with a time-variable coordinate transformation to formulate a two-dimensional numerical model that describes the evolution of gravity waves. The model is solved using a semi-Lagrangian method with monotone (nonoscillatory) interpolation of all advected fields. The time-variable transformation is used to generate disturbances at the lower boundary that approximate the effect of a traveling line of thunderstorms (a squall line) or of flow over a broad topographic obstacle. The vertical propagation and breaking of the gravity wave field (under conditions typical of summer solstice) is illustrated for each of these cases. It is shown that the wave field at high altitudes is dominated by a single horizontal wavelength; which is not always related simply to the horizontal dimension of the source. The morphology of wave breaking depends on the horizontal wavelength; for sufficiently short waves, breaking involves roughly one half of the wavelength. In common with other studies, it is found that the breaking waves undergo "self-acceleration," such that the zonal-mean intrinsic frequency remains approximately constant in spite of large changes in the background wind. It is also shown that many of the features obtained in the calculations can be understood in terms of linear wave theory. In particular, linear theory provides insights into the wavelength of the waves that break at high altitudes, the onset and evolution of breaking. the horizontal extent of the breaking region and its position relative to the forcing, and the minimum and maximum altitudes where breaking occurs. Wave breaking ceases at the altitude where the background dissipation rate (which in our model is a proxy for molecular diffusion) becomes greater than the rate of dissipation due to wave breaking, This altitude, in effect, the model turbopause, is shown to depend on a relatively small number of parameters that characterize the waves and the background state.

  16. Two-color infrared detector

    Science.gov (United States)

    Klem, John F; Kim, Jin K

    2014-05-13

    A two-color detector includes a first absorber layer. The first absorber layer exhibits a first valence band energy characterized by a first valence band energy function. A barrier layer adjoins the first absorber layer at a first interface. The barrier layer exhibits a second valence band energy characterized by a second valence band energy function. The barrier layer also adjoins a second absorber layer at a second interface. The second absorber layer exhibits a third valence band energy characterized by a third valence band energy function. The first and second valence band energy functions are substantially functionally or physically continuous at the first interface and the second and third valence band energy functions are substantially functionally or physically continuous at the second interface.

  17. Preventing High Altitude Cerebral Edema in Rats with Repurposed Anti-Angiogenesis Pharmacotherapy.

    Science.gov (United States)

    Tarshis, Samantha; Maltzahn, Joanne; Loomis, Zoe; Irwin, David C

    2016-12-01

    High altitude cerebral edema (HACE) is a fulminant, deadly, and yet still unpredictable brain disease. A new prophylactic treatment for HACE and its predecessor, acute mountain sickness (AMS), needs to be developed without the contraindications or adverse effect profiles of acetazolamide and dexamethasone. Since neovascularization signals are likely key contributors to HACE/AMS, our approach was to examine already existing anti-angiogenic drugs to inhibit potential initiating HACE pathway(s). This approach can also reveal crucial early steps in the frequently debated mechanism of HACE/AMS pathogenesis. We exposed four rat cohorts to hypobaric hypoxia and one to sea level (hyperbaric) conditions. The cohorts were treated with saline controls, an anti-angiogenesis drug (motesanib), a pro-angiogenesis drug (deferoxamine), or an intraperitoneal version of the established AMS prophylaxis drug, acetazolamide (benzolamide). Brain tissue was analyzed for cerebrovascular leak using the Evans Blue Dye (EVBD) protocol. We observed significantly increased EVBD in the altitude control and pro-angiogenesis (deferoxamine) cohorts, and significantly decreased EVBD in the anti-angiogenesis (motesanib), established treatment (benzolamide), and sea-level cohorts. Anti-angiogenesis-treated cohorts demonstrated less cerebrovascular extravasation than the altitude control and pro-angiogenesis treated rats, suggesting promise as an alternative prophylactic HACE/AMS treatment. The leak exacerbation with pro-angiogenesis treatment and improvement with anti-angiogenesis treatment support the hypothesis of early neovascularization signals provoking HACE. We demonstrate statistically significant evidence to guide further investigation for VEGF- and HIF-inhibitors as HACE/AMS prophylaxis, and as elucidators of still unknown HACE pathogenesis.Tarshis S, Maltzahn J, Loomis Z, Irwin DC. Preventing high altitude cerebral edema in rats with repurposed anti-angiogenesis pharmacotherapy. Aerosp Med

  18. High-altitude hypoxia as a therapeutic factor in the management of X-ray and cytostatic lymphocytopenias in cancer patients

    International Nuclear Information System (INIS)

    Kulish, u.P.; Galkina, K.A.; Karabekova, Z.K.; Kudryavtsev, V.I.; Gudi, T.P.

    1984-01-01

    An attempt is made to clarify possibilities of high-altitude conditions use in clinics to restore hematological indices deteriorating as a result of antitumoral radiation or cytostatic therapy. Using conventional methods the content of hemoglobin, the number of erythrocytes and leukocytes, leukocytic formula in the blood of patients have been determined. Using the method of hemocultures the ability of the blood serum to affect leukocyte migration of practically healthy people (donors) has been studied and by the method of amperometric titration the content of SH-groups in the blood is determined. In patients examined under high-altitude conditions the content of hemoglobin and the number of erythrocytes in blood increased, the level of total SH-groups of blood also grew. Blood serum of patients with the expressed lymphocytopenia instead of suppressing effect on leukocyte migration, observed under low-altitude conditions (Frunze), under high-altitude conditions attained the ability to increase leukocyte migration. The conclusion is made that high-altitude hypoxia is a positive factor in the treatment of radiation and cytostatic lymphopenias in cancer patients

  19. High-altitude diving in river otters: coping with combined hypoxic stresses.

    Science.gov (United States)

    Crait, Jamie R; Prange, Henry D; Marshall, Noah A; Harlow, Henry J; Cotton, Clark J; Ben-David, Merav

    2012-01-15

    River otters (Lontra canadensis) are highly active, semi-aquatic mammals indigenous to a range of elevations and represent an appropriate model for assessing the physiological responses to diving at altitude. In this study, we performed blood gas analyses and compared blood chemistry of river otters from a high-elevation (2357 m) population at Yellowstone Lake with a sea-level population along the Pacific coast. Comparisons of oxygen dissociation curves (ODC) revealed no significant difference in hemoglobin-oxygen (Hb-O(2)) binding affinity between the two populations - potentially because of demands for tissue oxygenation. Instead, high-elevation otters had greater Hb concentrations (18.7 g dl(-1)) than sea-level otters (15.6 g dl(-1)). Yellowstone otters displayed higher levels of the vasodilator nitric oxide (NO), and half the concentration of the serum protein albumin, possibly to compensate for increased blood viscosity. Despite compensation in several hematological and serological parameters, theoretical aerobic dive limits (ADL) were similar between high-elevation and sea-level otters because of the lower availability of O(2) at altitude. Our results suggest that recent disruptions to the Yellowstone Lake food web could be detrimental to otters because at this high elevation, constraints on diving may limit their ability to switch to prey in a deep-water environment.

  20. [Physical performance of older adults living in rural areas at sea level and at high altitude in Peru].

    Science.gov (United States)

    Estela-Ayamamani, David; Espinoza-Figueroa, Jossué; Columbus-Morales, Mauricio; Runzer-Colmenares, Fernando; Parodi, José F; Mayta-Tristán, Percy

    2015-01-01

    Living at high altitudes requires the inhabitants to adapt biologically and socially to the environment. The objective of this study was to determine the difference in physical performance (PP) in rural populations at sea level and at high altitude. A cross-sectional study was conducted in rural communities in Ancash, Peru, located at 3.345 meters above sea level (m.a.s.l.) and also in communities located in coastal areas at 6m.a.s.l. PP was measured by the Short Physical Performance Battery (SPPB) and other associated factors. Adjusted prevalence ratios (aPR) were calculated. A total of 130 older adults were assessed in the high altitude communities and 129 on the coast. The median age was 71.4 years, and 55.6% were female. Low physical performance (SPPB ≤ 6) was 10.0% at high altitude and 19.4% on the coast (p<0.05). Factors associated with low physical performance were residing at the coast (aPR: 2.10, 95% CI 1.02 to 4.33), self-reported poor health (aPR: 2.48, 95% CI 1.21 -5.08), hypertension (aPR: 1.73, 95% CI 1.01 to 2.98), and age (aPR: 1.04, 95% CI 1.01 to 1.07), while being a farmer (aPR: 0.49, 95% CI 0.25 to 0.97), and being independent (aPR: 0.37, 95% CI 0,20-, 072) were found to be protective factors. It was also found that the inhabitants of the coast have a mean of 0.86 points lower total SPPB than the high altitude ones (p=0.004). There is an association between altitude of residence and PP in older adults. The prevalence of a low PP in older adults in rural areas at sea level is twice as high compared to those living in high altitude rural communities. Copyright © 2014 SEGG. Published by Elsevier Espana. All rights reserved.

  1. Radiation Safety Issues in High Altitude Commercial Aircraft

    Science.gov (United States)

    Wilson, John W.; Cucinotta, Francis A.; Shinn, Judy L.

    1995-01-01

    The development of a global economy makes the outlook for high speed commercial intercontinental flight feasible, and the development of various configurations operating from 20 to 30 km have been proposed. In addition to the still unresolved issues relating to current commercial operations (12-16 km), the higher dose rates associated with the higher operating altitudes makes il imperative that the uncertainties in the atmospheric radiation environment and the associated health risks be re-examined. Atmospheric radiation associated with the galactic cosmic rays forms a background level which may, under some circumstances, exceed newly recommended allowable exposure limits proposed on the basis of recent evaluations of the A -bomb survivor data (due to increased risk coefficients). These larger risk coefficients, within the context of the methodology for estimating exposure limits, are resulting in exceedingly low estimated allowable exposure limits which may impact even present day flight operations and was the reason for the CEC workshop in Luxembourg (1990). At higher operating altitudes, solar particles events can produce exposures many orders of magnitude above background levels and pose significant health risks to the most sensitive individuals (such as during pregnancy). In this case the appropriate quality factors are undefined, and some evidence exists which indicates that the quality factor for stochastic effects is a substantial underestimate.

  2. High resolution RGB color line scan camera

    Science.gov (United States)

    Lynch, Theodore E.; Huettig, Fred

    1998-04-01

    A color line scan camera family which is available with either 6000, 8000 or 10000 pixels/color channel, utilizes off-the-shelf lenses, interfaces with currently available frame grabbers, includes on-board pixel by pixel offset correction, and is configurable and controllable via RS232 serial port for computer controlled or stand alone operation is described in this paper. This line scan camera is based on an available 8000 element monochrome line scan camera designed by AOA for OEM use. The new color version includes improvements such as better packaging and additional user features which make the camera easier to use. The heart of the camera is a tri-linear CCD sensor with on-chip color balancing for maximum accuracy and pinned photodiodes for low lag response. Each color channel is digitized to 12 bits and all three channels are multiplexed together so that the resulting camera output video is either a 12 or 8 bit data stream at a rate of up to 24Megpixels/sec. Conversion from 12 to 8 bit, or user-defined gamma, is accomplished by on board user-defined video look up tables. The camera has two user-selectable operating modes; lows speed, high sensitivity mode or high speed, reduced sensitivity mode. The intended uses of the camera include industrial inspection, digital archiving, document scanning, and graphic arts applications.

  3. Isolated psychosis during exposure to very high and extreme altitude - characterisation of a new medical entity.

    Science.gov (United States)

    Hüfner, Katharina; Brugger, Hermann; Kuster, Eva; Dünsser, Franziska; Stawinoga, Agnieszka E; Turner, Rachel; Tomazin, Iztok; Sperner-Unterweger, Barbara

    2017-12-05

    Psychotic episodes during exposure to very high or extreme altitude have been frequently reported in mountain literature, but not systematically analysed and acknowledged as a distinct clinical entity. Episodes reported above 3500 m altitude with possible psychosis were collected from the lay literature and provide the basis for this observational study. Dimensional criteria of the Diagnostic and Statistical Manual of Mental Disorders were used for psychosis, and the Lake Louise Scoring criteria for acute mountain sickness and high-altitude cerebral oedema (HACE). Eighty-three of the episodes collected underwent a cluster analysis to identify similar groups. Ratings were done by two independent, trained researchers (κ values 0.6-1). Findings Cluster 1 included 51% (42/83) episodes without psychosis; cluster 2 22% (18/83) cases with psychosis, plus symptoms of HACE or mental status change from other origins; and cluster 3 28% (23/83) episodes with isolated psychosis. Possible risk factors of psychosis and associated somatic symptoms were analysed between the three clusters and revealed differences regarding the factors 'starvation' (χ2 test, p = 0.002), 'frostbite' (p = 0.024) and 'supplemental oxygen' (p = 0.046). Episodes with psychosis were reversible but associated with near accidents and accidents (p = 0.007, odds ratio 4.44). Episodes of psychosis during exposure to high altitude are frequently reported, but have not been specifically examined or assigned to medical diagnoses. In addition to the risk of suffering from somatic mountain illnesses, climbers and workers at high altitude should be aware of the potential occurrence of psychotic episodes, the associated risks and respective coping strategies.

  4. An infrared view of high Tc superconductors

    International Nuclear Information System (INIS)

    Tanner, D.B.; Timusk, T.; McMaster Univ., Hamilton, ON

    1989-01-01

    Studies of the infrared properties of the high T c superconductors are reviewed, with particular emphasis on attempts to determine the energy gap by far infrared spectroscopy and on the properties of the strong absorption that occurs in the mid infrared. The authors argue that this mid-infrared absorption is a direct particle-hole excitation rather than a Holstein emission process. In addition, they conclude that although the energy gap is not easily observed, several recent experiments place it in the weak to moderate strong coupling range

  5. High altitude agriculture in the Titicaca basin (800 BCE-200 CE): Impacts on nutrition and disease load.

    Science.gov (United States)

    Juengst, Sara L; Hutchinson, Dale L; Chávez, Sergio J

    2017-07-08

    This study investigates the biological impacts of sedentism and agriculture on humans living in the high altitude landscape of the Titicaca Basin between 800 BCE and CE 200. The transition to agriculture in other global areas resulted in increases in disease and malnutrition; the high altitude of the Titicaca Basin could have exacerbated this. Our objective is to test whether the high altitude of the Titicaca Basin created a marginal environment for early agriculturalists living there, reflected through elevated rates of malnutrition and/or disease. To test this, we analyzed human remains excavated from seven archaeological sites on the Copacabana Peninsula for markers of diet and disease. These markers included dental caries, dental abscesses, cribra orbitalia, porotic hyperostosis, periosteal reactions, osteomyelitis, and linear enamel hypoplasia. Results showed that markers of diet did not support malnutrition or micronutrient deficiencies but instead, indicated a relatively diverse diet for all individuals. Markers of disease also did not vary significantly but were common, indicating circulation of pathogens or chronic bodily stress. We interpret these results as an indication that while diets remained nutritious, investment in the landscape exposed populations to issues of sanitation and disease. The high-altitude of the Titicaca Basin did not exacerbate the biological impacts of agriculture in terms of increased malnutrition. Additionally, disease load was likely related to problems faced by many sedentary groups as opposed to unique challenges posed by high altitude. In sum, despite the high elevation, the Titicaca Basin is not truly a marginal environment for humans. © 2017 Wiley Periodicals, Inc.

  6. EARLY SCIENCE WITH SOFIA, THE STRATOSPHERIC OBSERVATORY FOR INFRARED ASTRONOMY

    Energy Technology Data Exchange (ETDEWEB)

    Young, E. T.; Becklin, E. E.; De Buizer, J. M.; Andersson, B.-G.; Casey, S. C.; Helton, L. A. [SOFIA Science Center, Universities Space Research Association, NASA Ames Research Center, MS 232, Moffett Field, CA 94035 (United States); Marcum, P. M.; Roellig, T. L.; Temi, P. [NASA Ames Research Center, MS 232, Moffett Field, CA 94035 (United States); Herter, T. L. [Astronomy Department, 202 Space Sciences Building, Cornell University, Ithaca, NY 14853-6801 (United States); Guesten, R. [Max-Planck Institut fuer Radioastronomie, Auf dem Huegel 69, Bonn (Germany); Dunham, E. W. [Lowell Observatory, 1400 W. Mars Hill Rd., Flagstaff AZ 86001 (United States); Backman, D.; Burgdorf, M. [SOFIA Science Center, NASA Ames Research Center, MS 211-1, Moffett Field, CA 94035 (United States); Caroff, L. J.; Erickson, E. F. [NASA Ames Research Center, Moffett Field, CA 94035 (United States); Davidson, J. A. [School of Physics, The University of Western Australia (M013), 35 Stirling Highway, Crawley WA 6009 (Australia); Gehrz, R. D. [Minnesota Institute for Astrophysics, School of Physics and Astronomy, 116 Church Street, S. E., University of Minnesota, Minneapolis, MN 55455 (United States); Harper, D. A. [Yerkes Observatory, University of Chicago, 373 W. Geneva St., Williams Bay, WI (United States); Harvey, P. M. [Astronomy Department, University of Texas at Austin, 1 University Station C1400, Austin, TX 78712-0259 (United States); and others

    2012-04-20

    The Stratospheric Observatory For Infrared Astronomy (SOFIA) is an airborne observatory consisting of a specially modified Boeing 747SP with a 2.7 m telescope, flying at altitudes as high as 13.7 km (45,000 ft). Designed to observe at wavelengths from 0.3 {mu}m to 1.6 mm, SOFIA operates above 99.8% of the water vapor that obscures much of the infrared and submillimeter. SOFIA has seven science instruments under development, including an occultation photometer, near-, mid-, and far-infrared cameras, infrared spectrometers, and heterodyne receivers. SOFIA, a joint project between NASA and the German Aerospace Center Deutsches Zentrum fuer Luft und-Raumfahrt, began initial science flights in 2010 December, and has conducted 30 science flights in the subsequent year. During this early science period three instruments have flown: the mid-infrared camera FORCAST, the heterodyne spectrometer GREAT, and the occultation photometer HIPO. This Letter provides an overview of the observatory and its early performance.

  7. Three plasma metabolite signatures for diagnosing high altitude pulmonary edema

    Science.gov (United States)

    Guo, Li; Tan, Guangguo; Liu, Ping; Li, Huijie; Tang, Lulu; Huang, Lan; Ren, Qian

    2015-10-01

    High-altitude pulmonary edema (HAPE) is a potentially fatal condition, occurring at altitudes greater than 3,000 m and affecting rapidly ascending, non-acclimatized healthy individuals. However, the lack of biomarkers for this disease still constitutes a bottleneck in the clinical diagnosis. Here, ultra-high performance liquid chromatography coupled with Q-TOF mass spectrometry was applied to study plasma metabolite profiling from 57 HAPE and 57 control subjects. 14 differential plasma metabolites responsible for the discrimination between the two groups from discovery set (35 HAPE subjects and 35 healthy controls) were identified. Furthermore, 3 of the 14 metabolites (C8-ceramide, sphingosine and glutamine) were selected as candidate diagnostic biomarkers for HAPE using metabolic pathway impact analysis. The feasibility of using the combination of these three biomarkers for HAPE was evaluated, where the area under the receiver operating characteristic curve (AUC) was 0.981 and 0.942 in the discovery set and the validation set (22 HAPE subjects and 22 healthy controls), respectively. Taken together, these results suggested that this composite plasma metabolite signature may be used in HAPE diagnosis, especially after further investigation and verification with larger samples.

  8. Application of reflectance colorimeter measurements and infrared spectroscopy methods to rapid and nondestructive evaluation of carotenoids content in apricot (Prunus armeniaca L.).

    Science.gov (United States)

    Ruiz, David; Reich, Maryse; Bureau, Sylvie; Renard, Catherine M G C; Audergon, Jean-Marc

    2008-07-09

    The importance of carotenoid content in apricot (Prunus armeniaca L.) is recognized not only because of the color that they impart but also because of their protective activity against human diseases. Current methods to assess carotenoid content are time-consuming, expensive, and destructive. In this work, the application of rapid and nondestructive methods such as colorimeter measurements and infrared spectroscopy has been evaluated for carotenoid determination in apricot. Forty apricot genotypes covering a wide range of peel and flesh colors have been analyzed. Color measurements on the skin and flesh ( L*, a*, b*, hue, chroma, and a*/ b* ratio) as well as Fourier transform near-infrared spectroscopy (FT-NIR) on intact fruits and Fourier transform mid-infrared spectroscopy (FT-MIR) on ground flesh were correlated with the carotenoid content measured by high-performance liquid chromatography. A high variability in color values and carotenoid content was observed. Partial least squares regression analyses between beta-carotene content and provitamin A activity and color measurements showed a high fit in peel, flesh, and edible apricot portion (R(2) ranged from 0.81 to 0.91) and low prediction error. Regression equations were developed for predicting carotenoid content by using color values, which appeared as a simple, rapid, reliable, and nondestructive method. However, FT-NIR and FT-MIR models showed very low R(2) values and very high prediction errors for carotenoid content.

  9. Classifying coastal resources by integrating optical and radar imagery and color infrared photography

    Science.gov (United States)

    Ramsey, Elijah W.; Nelson, Gene A.; Sapkota, Sijan

    1998-01-01

    A progressive classification of a marsh and forest system using Landsat Thematic Mapper (TM), color infrared (CIR) photograph, and ERS-1 synthetic aperture radar (SAR) data improved classification accuracy when compared to classification using solely TM reflective band data. The classification resulted in a detailed identification of differences within a nearly monotypic black needlerush marsh. Accuracy percentages of these classes were surprisingly high given the complexities of classification. The detailed classification resulted in a more accurate portrayal of the marsh transgressive sequence than was obtainable with TM data alone. Individual sensor contribution to the improved classification was compared to that using only the six reflective TM bands. Individually, the green reflective CIR and SAR data identified broad categories of water, marsh, and forest. In combination with TM, SAR and the green CIR band each improved overall accuracy by about 3% and 15% respectively. The SAR data improved the TM classification accuracy mostly in the marsh classes. The green CIR data also improved the marsh classification accuracy and accuracies in some water classes. The final combination of all sensor data improved almost all class accuracies from 2% to 70% with an overall improvement of about 20% over TM data alone. Not only was the identification of vegetation types improved, but the spatial detail of the classification approached 10 m in some areas.

  10. FNTD radiation dosimetry system enhanced with dual-color wide-field imaging

    International Nuclear Information System (INIS)

    Akselrod, M.S.; Fomenko, V.V.; Bartz, J.A.; Ding, F.

    2014-01-01

    At high neutron and photon doses Fluorescent Nuclear Track Detectors (FNTDs) require operation in analog mode and the measurement results depend on individual crystal color center concentration (coloration). We describe a new method for radiation dosimetry using FNTDs, which includes non-destructive, automatic sensitivity calibration for each individual FNTD. In the method presented, confocal laser scanning fluorescent imaging of FNTDs is combined with dual-color wide field imaging of the FNTD. The calibration is achieved by measuring the color center concentration in the detector through fluorescence imaging and reducing the effect of diffuse reflection on the lapped surface of the FNTD by imaging with infra-red (IR) light. The dual-color imaging of FNTDs is shown to provide a good estimation of the detector sensitivity at high doses of photons and neutrons, where conventional track counting is impeded by track overlap. - Highlights: • New method and optical imaging head was developed for FNTD used at high doses. • Dual-color wide-field imaging used for color center concentration measurement. • Green fluorescence corrected by diffuse reflection used for sensitivity correction. • FNTD dose measurements performed in analog processing mode

  11. Altitude Stress During Participation of Medical Congress

    Science.gov (United States)

    Kim, Soon Bae; Kim, Jong Sung; Kim, Sang Jun; Cho, Su Hee

    2016-01-01

    Medical congresses often held in highlands. We reviewed several medical issues associated with altitude stress especially while physicians have participated medical congress held in high altitude. Altitude stress, also known as an acute mountain sickness (AMS), is caused by acute exposure to low oxygen level at high altitude which is defined as elevations at or above 1,200 m and AMS commonly occurs above 2,500 m. Altitude stress with various symptoms including insomnia can also be experienced in airplane. AMS and drunken state share many common features in symptoms, neurologic manifestations and even show multiple microbleeds in corpus callosum and white matter on MRI. Children are more susceptible to altitude stress than adults. Gradual ascent is the best method for the prevention of altitude stress. Adequate nutrition (mainly carbohydrates) and hydration are recommended. Consumption of alcohol can exacerbate the altitude-induced impairments in judgment and the visual senses and promote psychomotor dysfunction. For prevention or treatment of altitude stress, acetazolamide, phosphodiesterase inhibitors, dexamethasone and erythropoietin are helpful. Altitude stress can be experienced relatively often during participation of medical congress. It is necessary to remind the harmful effect of AMS because it can cause serious permanent organ damage even though the symptoms are negligible in most cases. PMID:27621942

  12. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Nuristan mineral district in Afghanistan

    Science.gov (United States)

    Davis, Philip A.; Cagney, Laura E.; Arko, Scott A.; Harbin, Michelle L.; Davis, Philip A.

    2013-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Nuristan mineral district, which has gem, lithium, and cesium deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420–500 nanometer, nm), green (520–600 nm), red (610–690 nm), and near-infrared (760–890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520–770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency (©JAXA,2008,2009), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be recreated from this DS

  13. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the Ahankashan mineral district in Afghanistan

    Science.gov (United States)

    Davis, Philip A.; Davis, Philip A.

    2013-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the Ahankashan mineral district, which has copper and gold deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420–500 nanometer, nm), green (520–600 nm), red (610–690 nm), and near-infrared (760–890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520–770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency (©JAXA,2007,2008, 2009, 2010),but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be recreated from this

  14. Electromagnetic coupling of high-altitude, nuclear electromagnetic pulses

    International Nuclear Information System (INIS)

    Anon.

    1984-01-01

    We have used scale models to measure the predicted coupling of electromagnetic fields simulating the effects of high-altitude nuclear electromagnetic pulses (HEMP) on the interior surfaces of electronic components. Predictive tools for exterior coupling are adequate. For interior coupling, however, such tools are in their infancy. Our methodological approach combines analytical, computational, and laboratory techniques in a complementary way to take advantage of their separate strengths. Computer models are a promising tool, as they can be used to treat complex objects with arbitrary shapes, dielectrics, and cables, and multiple apertures. Laboratory tests can expand the domain of investigation even further

  15. DISCOVERING THE MISSING 2.2 < z < 3 QUASARS BY COMBINING OPTICAL VARIABILITY AND OPTICAL/NEAR-INFRARED COLORS

    International Nuclear Information System (INIS)

    Wu Xuebing; Wang Ran; Bian Fuyan; Jiang Linhua; Fan Xiaohui; Schmidt, Kasper B.

    2011-01-01

    The identification of quasars in the redshift range 2.2 < z < 3 is known to be very inefficient because the optical colors of such quasars are indistinguishable from those of stars. Recent studies have proposed using optical variability or near-infrared (near-IR) colors to improve the identification of the missing quasars in this redshift range. Here we present a case study combining both methods. We select a sample of 70 quasar candidates from variables in Sloan Digital Sky Survey (SDSS) Stripe 82, which are non-ultraviolet excess sources and have UKIDSS near-IR public data. They are clearly separated into two parts on the Y - K/g - z color-color diagram, and 59 of them meet or lie close to a newly proposed Y - K/g - z selection criterion for z < 4 quasars. Of these 59 sources, 44 were previously identified as quasars in SDSS DR7, and 35 of them are quasars at 2.2 < z < 3. We present spectroscopic observations of 14 of 15 remaining quasar candidates using the Bok 2.3 m telescope and the MMT 6.5 m telescope, and successfully identify all of them as new quasars at z = 2.36-2.88. We also apply this method to a sample of 643 variable quasar candidates with SDSS-UKIDSS nine-band photometric data selected from 1875 new quasar candidates in SDSS Stripe 82 given by Butler and Bloom based on the time-series selections, and find that 188 of them are probably new quasars with photometric redshifts at 2.2 < z < 3. Our results indicate that the combination of optical variability and optical/near-IR colors is probably the most efficient way to find 2.2 < z < 3 quasars and is very helpful for constructing a complete quasar sample. We discuss its implications for ongoing and upcoming large optical and near-IR sky surveys.

  16. The yak genome and adaptation to life at high altitude

    DEFF Research Database (Denmark)

    Qiu, Qiang; Zhang, Guojie; Ma, Tao

    2012-01-01

    . Here, we present the draft genome sequence of a female domestic yak generated using Illumina-based technology at 65-fold coverage. Genomic comparisons between yak and cattle identify an expansion in yak of gene families related to sensory perception and energy metabolism, as well as an enrichment...... important implications for understanding adaptation to high altitude in other animal species and for hypoxia-related diseases in humans....

  17. Long-Term Intermittent Work at High Altitude: Right Heart Functional and Morphological Status and Associated Cardiometabolic Factors

    Directory of Open Access Journals (Sweden)

    Julio Brito

    2018-03-01

    Full Text Available Background: Living at high altitude or with chronic hypoxia implies functional and morphological changes in the right ventricle and pulmonary vasculature with a 10% prevalence of high-altitude pulmonary hypertension (HAPH. The implications of working intermittently (day shifts at high altitude (hypobaric hypoxia over the long term are still not well-defined. The aim of this study was to evaluate the right cardiac circuit status along with potentially contributory metabolic variables and distinctive responses after long exposure to the latter condition.Methods: A cross-sectional study of 120 healthy miners working at an altitude of 4,400–4,800 m for over 5 years in 7-day commuting shifts was designed. Echocardiography was performed on day 2 at sea level. Additionally, biomedical and biochemical variables, Lake Louise scores (LLSs, sleep disturbances and physiological variables were measured at altitude and at sea level.Results: The population was 41.8 ± 0.7 years old, with an average of 14 ± 0.5 (range 5–29 years spent at altitude. Most subjects still suffered from mild to moderate symptoms of acute mountain sickness (mild was an LLS of 3–5 points, including cephalea; moderate was LLS of 6–10 points (38.3% at the end of day 1 of the shift. Echocardiography showed a 23% mean pulmonary artery pressure (mPAP >25 mmHg, 9% HAPH (≥30 mmHg, 85% mild increase in right ventricle wall thickness (≥5 mm, 64% mild right ventricle dilation, low pulmonary vascular resistance (PVR and fairly good ventricle performance. Asymmetric dimethylarginine (ADMA (OR 8.84 (1.18–66.39; p < 0.05 and insulin (OR: 1.11 (1.02–1.20; p < 0.05 were associated with elevated mPAP and were defined as a cut-off. Interestingly, the correspondence analysis identified association patterns of several other variables (metabolic, labor, and biomedical with higher mPAP.Conclusions: Working intermittently at high altitude involves a distinctive pattern. The most relevant and

  18. Use of ocean color scanner data in water quality mapping

    Science.gov (United States)

    Khorram, S.

    1981-01-01

    Remotely sensed data, in combination with in situ data, are used in assessing water quality parameters within the San Francisco Bay-Delta. The parameters include suspended solids, chlorophyll, and turbidity. Regression models are developed between each of the water quality parameter measurements and the Ocean Color Scanner (OCS) data. The models are then extended to the entire study area for mapping water quality parameters. The results include a series of color-coded maps, each pertaining to one of the water quality parameters, and the statistical analysis of the OCS data and regression models. It is found that concurrently collected OCS data and surface truth measurements are highly useful in mapping the selected water quality parameters and locating areas having relatively high biological activity. In addition, it is found to be virtually impossible, at least within this test site, to locate such areas on U-2 color and color-infrared photography.

  19. Upward Shift and Steepening of the Blood Pressure Response to Exercise in Hypertensive Subjects at High Altitude.

    Science.gov (United States)

    Caravita, Sergio; Faini, Andrea; Baratto, Claudia; Bilo, Grzegorz; Macarlupu, Josè Luis; Lang, Morin; Revera, Miriam; Lombardi, Carolina; Villafuerte, Francisco C; Agostoni, Piergiuseppe; Parati, Gianfranco

    2018-06-09

    Acute exposure to high-altitude hypobaric hypoxia induces a blood pressure rise in hypertensive humans, both at rest and during exercise. It is unclear whether this phenomenon reflects specific blood pressure hyperreactivity or rather an upward shift of blood pressure levels. We aimed at evaluating the extent and rate of blood pressure rise during exercise in hypertensive subjects acutely exposed to high altitude, and how these alterations can be counterbalanced by antihypertensive treatment. Fifty-five subjects with mild hypertension, double-blindly randomized to placebo or to a fixed-dose combination of an angiotensin-receptor blocker (telmisartan 80 mg) and a calcium-channel blocker (nifedipine slow release 30 mg), performed a cardiopulmonary exercise test at sea level and after the first night's stay at 3260 m altitude. High-altitude exposure caused both an 8 mm Hg upward shift ( P blood pressure/oxygen consumption relationship during exercise, independent of treatment. Telmisartan/nifedipine did not modify blood pressure reactivity to exercise (blood pressure/oxygen consumption slope), but downward shifted ( P blood pressure and oxygen consumption by 26 mm Hg, both at sea level and at altitude. Muscle oxygen delivery was not influenced by altitude exposure but was higher on telmisartan/nifedipine than on placebo ( P blood pressure response to exercise. The effect of the combination of telmisartan/nifedipine slow release outweighed these changes and was associated with better muscle oxygen delivery. URL: http://www.clinicaltrials.gov. Unique identifier: NCT01830530. © 2018 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

  20. Angiotensin-converting enzyme (ACE) alleles in the Quechua, a high altitude South American native population.

    Science.gov (United States)

    Rupert, J L; Devine, D V; Monsalve, M V; Hochachka, P W

    1999-01-01

    Recently it was reported that an allelic variant of the gene encoding angiotensin-converting enzyme (ACE) was significantly over-represented in a cohort of elite British mountaineers. It was proposed that this may be evidence for a specific genetic factor influencing the human capacity for physical performance. The implication that this allele could enhance performance at high altitude prompted us to determine its frequency in Quechua speaking natives living at altitudes greater than 3000m on the Andean Altiplano in South America. We found that the frequency of the putative performance allele in the Quechuas, although significantly higher than in Caucasians, was not different from lowland Native American populations. This observation suggests that, although the higher frequency of the 'performance allele' may have facilitated the migration of the ancestral Quechua to the highlands, the ACE insertion allele has not been subsequently selected for in this high altitude population.

  1. Anthropometric survey of high-altitude Bolivian porters.

    Science.gov (United States)

    Leatherman, T L; Thomas, R B; Greksa, L P; Haas, J D

    1984-01-01

    This paper presents the results of an anthropometric survey of 138 rural Aymaran high-altitude males who were working as porters in La Paz, Bolivia (3700 m). All subjects were measured for stature, weight, upper arm circumference, and triceps skinfolds. The body size and composition of the porters were then compared to an Aymaran rural population from the Bolivian highlands, and urban mestizo labourers from La Paz. The porters were smaller than the urban sample, but appeared to be generally representative of rural Aymaran natives with respect to body size and composition, and nutritional status. It is suggested that towards one extreme of nutritional variability, some degree of undernutrition may be indicated, which should be considered in future studies of adaptation to hypoxia among these Andean highlanders.

  2. The peak altitude of H3+ auroral emission: comparison with the ultraviolet

    Science.gov (United States)

    Blake, J.; Stallard, T.; Miller, S.; Melin, H.; O'Donoghue, J.; Baines, K.

    2013-09-01

    The altitude of Saturn's peak auroral emission has previously been measured for specific cases in both the ultraviolet (UV) and the infrared (IR). Gerard et al [2009] concludes that the night side H2 UV emission is within the range of 800 to 1300 km above the 1-bar pressure surface. However, using colour ratio spectroscopy, Gustin et al [2009] located the emission layer at or above 610 km. Measurements of the infrared auroral altitude was conducted by Stallard et al [2012] on H3+ emissions from nine VIMS Cassini images, resulting in a measurement of 1155 ± 25 km above the 1-bar pressure surface. Here we present data analysed in a manner similar to Stallard et al [2012] on the observations of H3+ emission in twenty images taken by the Visual Infrared Mapping Spectrometer (VIMS) aboard the spacecraft Cassini from the years 2006, 2008 and 2012. The bins covered were 3.39872, 3.51284, 3.64853, 4.18299 and 4.33280 μm. These observations were selected from a set of 15,000 as they contained a useful alignment of the aurorae on the limb and the body of the planet. The specific conditions that had to be met for each image were as follows; minimum integration time of 75 milliseconds per pixel, minimum number of pixels in the x and y direction of 32, the image must include the latitude range of 70 to 90 degrees for either hemisphere and the sub spacecraft angle must be between 0 and 20 degrees. This alignment allowed for the altitudinal profiles to be analysed in terms of the difference between the latitude of aurorae on the limb and on the body of Saturn; thus permitting an investigation into the effects of misalignment. In this instance, misalignment was defined as the difference between the latitude of the peak emission latitude on the planet and the latitude of the limb; assuming the aurorae to be approximately circular. A statistical study by Badman et al [2011] showed that centre of the oval is on average offset anti sunward of the pole by about 1.6 degrees. To

  3. EXAFS analysis of full color glasses and glass ceramics: local order and color

    International Nuclear Information System (INIS)

    Santa Cruz, Petrus A.; Sa, Gilberto F. de; Malta, Oscar L.; Silva, Jose expedito Cavalcante

    1996-01-01

    The generation and control of the relative intensities of the primary additive colors in solid state light emitters is very important to the development of higher resolution media, used in color monitors, solid state sensors, large area and flat displays and other optoelectronic devices. We have developed a multi-doped glassy material named FCG (full color glass, to generate and to control the primary light colors, allowing the simulation of any color of light by additive synthesis. Tm(III), Tb(III) and Eu(III) ions were used (0.01 to 5.0 mol%) as blue, green and red narrow emitters. A wide color gamut was obtained under ultraviolet excitation by varying the material composition. The chromaticity diagram is covered, including the white simulation. We proposed a mechanism to control the chromaticity of a fixed composition of the material, using the Er (III) as a selective quencher that may be deactivated by infrared excitation. Although this new material presents at this time a high efficiency, it may be improved because the energy transfer between the rare earth triad may be still reduced. Optical spectroscopy measurements confirms that it is still possible to improve the efficiency of the FCC material. EXAFS analysis will be used to probe the local environment around the triad of rare earth that generates the primary colors. For this purpose we have prepared single doped glasses with each component of the triad with the same concentration than FCG. The devitrification of these glasses will be analyzed in order to produce glassceramics with ion segregation. (author)

  4. Hydrological processes in glacierized high-altitude basins of the western Himalayas

    Science.gov (United States)

    Jeelani, Ghulam; Shah, Rouf A.; Fryar, Alan E.; Deshpande, Rajendrakumar D.; Mukherjee, Abhijit; Perrin, Jerome

    2018-03-01

    Western Himalaya is a strategically important region, where the water resources are shared by China, India and Pakistan. The economy of the region is largely dependent on the water resources delivered by snow and glacier melt. The presented study used stable isotopes of water to further understand the basin-scale hydro-meteorological, hydrological and recharge processes in three high-altitude mountainous basins of the western Himalayas. The study provided new insights in understanding the dominant factors affecting the isotopic composition of the precipitation, snowpack, glacier melt, streams and springs. It was observed that elevation-dependent post-depositional processes and snowpack evolution resulted in the higher isotopic altitude gradient in snowpacks. The similar temporal trends of isotopic signals in rivers and karst springs reflect the rapid flow transfer due to karstification of the carbonate aquifers. The attenuation of the extreme isotopic input signal in karst springs appears to be due to the mixing of source waters with the underground karst reservoirs. Basin-wise, the input-output response demonstrates the vital role of winter precipitation in maintaining the perennial flow in streams and karst springs in the region. Isotopic data were also used to estimate the mean recharge altitude of the springs.

  5. High-resolution altitude profiles of the atmospheric turbulence with PML at the Sutherland Observatory

    Science.gov (United States)

    Catala, L.; Ziad, A.; Fanteï-Caujolle, Y.; Crawford, S. M.; Buckley, D. A. H.; Borgnino, J.; Blary, F.; Nickola, M.; Pickering, T.

    2017-05-01

    With the prospect of the next generation of ground-based telescopes, the extremely large telescopes, increasingly complex and demanding adaptive optics systems are needed. This is to compensate for image distortion caused by atmospheric turbulence and fully take advantage of mirrors with diameters of 30-40 m. This requires a more precise characterization of the turbulence. The Profiler of Moon Limb (PML) was developed within this context. The PML aims to provide high-resolution altitude profiles of the turbulence using differential measurements of the Moon limb position to calculate the transverse spatio-angular covariance of the angle of arrival fluctuations. The covariance of differential image motion for different separation angles is sensitive to the altitude distribution of the seeing. The use of the continuous Moon limb provides a large number of separation angles allowing for the high-resolution altitude of the profiles. The method is presented and tested with simulated data. Moreover, a PML instrument was deployed at the Sutherland Observatory in South Africa in 2011 August. We present here the results of this measurement campaign.

  6. Effect of high altitude cosmic irradiation upon cell generation time

    International Nuclear Information System (INIS)

    Soleilhavoup, J.P.; Croute, F.; Tixador, R.; Blanquet, Y.; Planel, H.

    1975-01-01

    Paramecia cultures placed at 3800 meter altitude show a proliferating activity acceleration compared to control cultures placed at low altitude under the same environment conditions. These results confirm the cosmic irradiation influence upon the activating effect produced by the natural ionizing radiations on living organisms [fr

  7. High Altitude Venus Operations Concept Trajectory Design, Modeling and Simulation

    Science.gov (United States)

    Lugo, Rafael A.; Ozoroski, Thomas A.; Van Norman, John W.; Arney, Dale C.; Dec, John A.; Jones, Christopher A.; Zumwalt, Carlie H.

    2015-01-01

    A trajectory design and analysis that describes aerocapture, entry, descent, and inflation of manned and unmanned High Altitude Venus Operation Concept (HAVOC) lighter-than-air missions is presented. Mission motivation, concept of operations, and notional entry vehicle designs are presented. The initial trajectory design space is analyzed and discussed before investigating specific trajectories that are deemed representative of a feasible Venus mission. Under the project assumptions, while the high-mass crewed mission will require further research into aerodynamic decelerator technology, it was determined that the unmanned robotic mission is feasible using current technology.

  8. Interactions of carbon monoxide and hemoglobin at high altitude

    Energy Technology Data Exchange (ETDEWEB)

    Collier, C.R. (Univ. of Southern California Medical Center, Los Angeles); Goldsmith, J.R.

    1983-01-01

    The health risks to U.S. populations who are exposed to ambient carbon monoxide and live at altitudes (such as Denver, Salt Lake City, and Albuquerque) were evaluated using a set of mathematical models. The assumption that a given increase in carboxyhemoglobin would require a more stringent volumetric air quality standard was tested. The results using the model predict that the 8-h or 1-h standards adopted for sea level condition need not be altered to protect individuals against health risks at altitude, if the standards are in volumetric terms. They would need to be reduced if the standards are left in gravimetric terms. If the guideline is to be based on a given decrement of oxygen tension, many other variables must be specified, but expected differences in ambient carbon monoxide have a small impact compared to the effect of altitude itself.

  9. Performance simulation in high altitude platforms (HAPs) communications systems

    Science.gov (United States)

    Ulloa-Vásquez, Fernando; Delgado-Penin, J. A.

    2002-07-01

    This paper considers the analysis by simulation of a digital narrowband communication system for an scenario which consists of a High-Altitude aeronautical Platform (HAP) and fixed/mobile terrestrial transceivers. The aeronautical channel is modelled considering geometrical (angle of elevation vs. horizontal distance of the terrestrial reflectors) and statistical arguments and under these circumstances a serial concatenated coded digital transmission is analysed for several hypothesis related to radio-electric coverage areas. The results indicate a good feasibility for the communication system proposed and analysed.

  10. High-altitude wind resources in the Middle East

    KAUST Repository

    Yip, Chak Man Andrew; Gunturu, Udaya; Stenchikov, Georgiy L.

    2017-01-01

    In the Middle East, near-surface wind resources are intermittent. However, high-altitude wind resources are abundant, persistent, and readily available and may provide alternative energy resources in this fossil-fuel-dependent region. Using wind field data from the Modern-Era Retrospective Analysis for Research and Applications Version 2 (MERRA-2), this study identifies areas favorable to the deployment of airborne wind energy (AWE) systems in the Middle East and computes the optimal heights at which such systems would best operate. AWE potential is estimated using realistic AWE system specifications and assumptions about deployment scenarios and is compared with the near-surface wind generation potential with respect to diurnal and seasonal variability. The results show the potential utility of AWE in areas in the Middle East where the energy demand is high. In particular, Oman and Saudi Arabia have a high level of the potential power generation with low annual variability.

  11. High-altitude wind resources in the Middle East

    KAUST Repository

    Yip, Chak Man Andrew

    2017-08-23

    In the Middle East, near-surface wind resources are intermittent. However, high-altitude wind resources are abundant, persistent, and readily available and may provide alternative energy resources in this fossil-fuel-dependent region. Using wind field data from the Modern-Era Retrospective Analysis for Research and Applications Version 2 (MERRA-2), this study identifies areas favorable to the deployment of airborne wind energy (AWE) systems in the Middle East and computes the optimal heights at which such systems would best operate. AWE potential is estimated using realistic AWE system specifications and assumptions about deployment scenarios and is compared with the near-surface wind generation potential with respect to diurnal and seasonal variability. The results show the potential utility of AWE in areas in the Middle East where the energy demand is high. In particular, Oman and Saudi Arabia have a high level of the potential power generation with low annual variability.

  12. Reduced prefrontal cortex activation in the color-word Stroop task for Chinese dyslexic children: a near-infrared spectroscopy study

    International Nuclear Information System (INIS)

    Sun Jinyan; Zhai Jiahuan; Gong Hui; Song Ranran; Zou Li

    2011-01-01

    Behavioral studies have investigated the performance of children with developmental dyslexia in conflict resolution, a function connected with the prefrontal cortex (PFC) closely. However, little is known about the prefrontal activation in conflict resolution for dyslexic children. In the present study, the involvement of the PFC in resolving conflict was evaluated for Chinese dyslexic children by means of near-infrared spectroscopy (NIRS). The NIRS instrument is a portable, continuous-wave system and can measure concentration changes of hemodynamic parameters (including oxy-, deoxy-, and total hemoglobin). Considering better sensitivity, the oxy-hemoglobin (oxy-Hb) was chosen to indicate the prefrontal activation. Ten dyslexic children and 11 normal children were recruited to perform the Chinese-character color-word Stroop task, which included the neutral and color (incongruent) tasks. In behavioral performance, both groups showed significant Stroop effect, longer response time or higher error rate for the color task. In particular, the Stroop interference effect was marginally larger for dyslexic children than normal children in response time. What's more, the two groups showed distinct pattern of oxy-Hb activation during the Stroop tasks. The normal group recruited the bilateral PFC to perform the tasks, while the dyslexic group couldn't activate the bilateral PFC in the difficult color task. Moreover, significantly less color Stroop effect was found in the left PFC for the dyslexic group, showing their disability in coping with the Stroop interference. These findings suggest that the PFC is dysfunctional in conflict resolution for Chinese dyslexic children and that NIRS can be an effective tool in neurological research and clinical application.

  13. Reduced prefrontal cortex activation in the color-word Stroop task for Chinese dyslexic children: a near-infrared spectroscopy study

    Energy Technology Data Exchange (ETDEWEB)

    Sun Jinyan; Zhai Jiahuan; Gong Hui [Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics-Huazhong University of Science and Technology, Wuhan 430074 (China); Song Ranran; Zou Li, E-mail: huigong@mail.hust.edu.cn [Department of Child and Adolescent Health and Maternal Care, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430074 (China)

    2011-01-01

    Behavioral studies have investigated the performance of children with developmental dyslexia in conflict resolution, a function connected with the prefrontal cortex (PFC) closely. However, little is known about the prefrontal activation in conflict resolution for dyslexic children. In the present study, the involvement of the PFC in resolving conflict was evaluated for Chinese dyslexic children by means of near-infrared spectroscopy (NIRS). The NIRS instrument is a portable, continuous-wave system and can measure concentration changes of hemodynamic parameters (including oxy-, deoxy-, and total hemoglobin). Considering better sensitivity, the oxy-hemoglobin (oxy-Hb) was chosen to indicate the prefrontal activation. Ten dyslexic children and 11 normal children were recruited to perform the Chinese-character color-word Stroop task, which included the neutral and color (incongruent) tasks. In behavioral performance, both groups showed significant Stroop effect, longer response time or higher error rate for the color task. In particular, the Stroop interference effect was marginally larger for dyslexic children than normal children in response time. What's more, the two groups showed distinct pattern of oxy-Hb activation during the Stroop tasks. The normal group recruited the bilateral PFC to perform the tasks, while the dyslexic group couldn't activate the bilateral PFC in the difficult color task. Moreover, significantly less color Stroop effect was found in the left PFC for the dyslexic group, showing their disability in coping with the Stroop interference. These findings suggest that the PFC is dysfunctional in conflict resolution for Chinese dyslexic children and that NIRS can be an effective tool in neurological research and clinical application.

  14. Genetic variants in EPAS1 contribute to adaptation to high-altitude hypoxia in Sherpas.

    Directory of Open Access Journals (Sweden)

    Masayuki Hanaoka

    Full Text Available Sherpas comprise a population of Tibetan ancestry in the Himalayan region that is renowned for its mountaineering prowess. The very small amount of available genetic information for Sherpas is insufficient to explain their physiological ability to adapt to high-altitude hypoxia. Recent genetic evidence has indicated that natural selection on the endothelial PAS domain protein 1 (EPAS1 gene was occurred in the Tibetan population during their occupation in the Tibetan Plateau for millennia. Tibetan-specific variations in EPAS1 may regulate the physiological responses to high-altitude hypoxia via a hypoxia-inducible transcription factor pathway. We examined three significant tag single-nucleotide polymorphisms (SNPs, rs13419896, rs4953354, and rs4953388 in the EPAS1 gene in Sherpas, and compared these variants with Tibetan highlanders on the Tibetan Plateau as well as with non-Sherpa lowlanders. We found that Sherpas and Tibetans on the Tibetan Plateau exhibit similar patterns in three EPAS1 significant tag SNPs, but these patterns are the reverse of those in non-Sherpa lowlanders. The three SNPs were in strong linkage in Sherpas, but in weak linkage in non-Sherpas. Importantly, the haplotype structured by the Sherpa-dominant alleles was present in Sherpas but rarely present in non-Sherpas. Surprisingly, the average level of serum erythropoietin in Sherpas at 3440 m was equal to that in non-Sherpas at 1300 m, indicating a resistant response of erythropoietin to high-altitude hypoxia in Sherpas. These observations strongly suggest that EPAS1 is under selection for adaptation to the high-altitude life of Tibetan populations, including Sherpas. Understanding of the mechanism of hypoxia tolerance in Tibetans is expected to provide lights to the therapeutic solutions of some hypoxia-related human diseases, such as cardiovascular disease and cancer.

  15. Optimization of mooseer (A. hirtifolium Boiss.) dehydration under infrared conditions.

    Science.gov (United States)

    Chayjan, Reza Amiri; Fealekari, Mosayeb

    2017-01-01

    In recent years, infrared drying has gained popularity as an alternative drying method for a va- riety of agricultural products. The use of infrared radiation technology in drying agricultural products has several advantages. These may include decreased drying time, high energy efficiency, high-quality finished products and uniform temperature in the product. With intermittent infrared and convection heating of a thick porous material, the drying time can be reduced compared to convection alone, while keeping good food quality and high energy efficiency. Response surface methodology (RSM) was employed to optimize the drying con- ditions of mooseer under infrared-convective drying. Experiments were performed at air temperatures of  40, 55 and 70°C, infrared powers of 500, 1000 and 1500 W, air velocities of 0.5, 1.5 and 2.5 m/s and slice thicknesses of 2, 4, and 6 mm. In this study, effective moisture diffusivity (Deff), shrinkage, color changes and specific energy consumption (SEC) were investigated. The central composite design (CCD) was selected for the design and optimization of the process. Deff was obtained between 1.4×10 and 3.57×10    m /s. With increasing air temperature and slice –10                                  –9       2 thickness, Deff also increased. The level of shrinkage rose as slice thickness increased. The highest and lowest values of color changes were calculated at air temperatures of 70°C (52.3%) and 40°C (5.65%), respectively. Increasing air velocity led to an increase in SEC. Optimum conditions for mooseer drying were achieved at air temperature of 70°C, infrared power of 867.46, air velocity of 0.59 m/s and slice thickness of 2 mm. At this point, Deff, shrinkage, color changes and SEC was obtained as 1.32×10–9 m2/s, 29.58%, 17.62% and 4.64 MJ/kg, respectively. The desir- ability value of 0.689 was achieved for the drying process.  .

  16. Using cuttlefish ink as an additive to produce -non-iridescent structural colors of high color visibility.

    Science.gov (United States)

    Zhang, Yafeng; Dong, Biqin; Chen, Ang; Liu, Xiaohan; Shi, Lei; Zi, Jian

    2015-08-26

    Non-iridescent structural colors of high color visibility are produced by amorphous photonic structures, in which -natural cuttlefish ink is used as an additive to break down the long-range order of the structures. The color hue and its spectral purity can be tuned by adjusting the diameter of the polystyrene (PS) spheres and the proportion of ink particles. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. Far infrared observations of the galactic center

    International Nuclear Information System (INIS)

    Gatley, I.

    1977-01-01

    Maps of a region 10' in diameter around the galactic center made simultaneously in three wavelength bands at 30 μm, 50 μm, and 100 μm with approximately 1' resolution are presented, and the distribution of far infrared luminosity and color temperature across this region is derived. The position of highest far infrared surface brightness coincides with the peak of the late-type stellar distribution and with the H II region Sgr A West. The high spatial and temperature resolution of the data is used to identify features of the far infrared maps with known sources of near infrared, radio continuum, and molecular emission. The emission mechanism and energy sources for the far infrared radiation are anslyzed qualitatively, and it is concluded that all of the observed far infrared radiation from the galactic center region can be attributed to thermal emission from dust heated both by the late-type stars and by the ultraviolet sources which ionize the H II regions. A self-consistent model for the far infrared emission from the galactic center region is presented. It is found that the visual extinction across the central 10 pc of the galaxy is only about 3 magnitudes, and that the dust density is fairly uniform in this region. An upper limit of 10 7 L/sub mass/ is set on the luminosity of any presently unidentified source of 0.1 to 1 μm radiation at the galactic center. Additional maps in the vicinity of the source Sgr B2 and observations of Sgr C bring the total number of H II regions within 1 0 of the galactic center studied by the present experiment to nine. The far infrared luminosity, color temperature and optical depth of these regions and the ratio of infrared flux to radio continuum flux lie in the range characteristic of spiral arm H II regions. The far infrared results are therefore consistent with the data that the galactic center H II regions are ionized by luminous, early type stars

  18. Influence of colorant and film thickness on thermal aging characteristics of oxo-biodegradable plastic bags

    Science.gov (United States)

    Leuterio, Giselle Lou D.; Pajarito, Bryan B.; Domingo, Carla Marie C.; Lim, Anna Patricia G.

    2016-05-01

    Functional, lightweight, strong and cheap plastic bags incorporated with pro-oxidants undergo accelerated degradation under exposure to heat and oxygen. This work investigated the effect of colorant and film thickness on thermal aging characteristics of commercial oxo-biodegradable plastic bag films at 70 °C. Degradation is monitored through changes in infrared absorption, weight, and tensile properties of thermally aged films. The presence of carbonyl band in infrared spectrum after 672 h of thermal aging supports the degradation behavior of exposed films. Results show that incorporation of colorant and increasing thickness exhibit low maximum weight uptake. Titanium dioxide as white colorant in films lowers the susceptibility of films to oxygen uptake but enhances physical degradation. Higher amount of pro-oxidant loading also contributes to faster degradation. Opaque films are characterized by low tensile strength and high elastic modulus. Decreasing the thickness contributes to lower tensile strength of films. Thermally aged films with colorant and low thickness promote enhanced degradation.

  19. Oviposition of aquatic insects in a tropical high altitude stream.

    Science.gov (United States)

    Rios-Touma, Blanca; Encalada, A C; Prat, N

    2012-12-01

    The persistence of aquatic insect populations in streams depends on the recruitment of larval populations from egg masses deposited by adults, especially after disturbance. However, recruitment of aquatic populations by oviposition is a process that remains unstudied in streams and rivers. The objectives of our study were to document flying and oviposition patterns of aquatic insects in a high altitude tropical stream during both dry and wet seasons. In particular we studied 1) richness and abundance of adult forms of aquatic insects flying and ovipositing; 2) number of eggs (oviposition pattern), egg mass identity, and morphology; and 3) substrate preferences by ovipositing females. We found 2,383 aquatic insects corresponding to 28 families, with dipterans representing 89% of total individuals collected. Adult insects had lower richness (28 taxa) than larval diversity (up to 52 taxa) and distinct community composition. Richness and relative abundance of most taxa (adults) were not significantly different between seasons, behaviors, diel period, or all three. During both sampling periods we found females with eggs in a total of 15 different families (13 in the dry season and 14 in the wet season). There were no significant differences in the proportion of females with eggs between seasons, diel periods, or different behaviors (flying versus ovipositing traps) of the different female taxa. Few types of egg masses were found in rocks at the stream during both seasons, and most egg masses found corresponded to families Baetidae and Chironomidae. Finally, we provide the first description of eggs masses (size, shape, color, and number of eggs per female) of gravid females (10 taxa) and those found in the stream substrate (six taxa) of Andean macroinvertebrates. This is the first study reporting oviposition, adult diversity, and oviposition patterns of aquatic insects in the Andean region.

  20. Moessbauer studies of hemoglobin in high altitude polycythemia

    International Nuclear Information System (INIS)

    Zhang Xiufang; Shen Linming; Chen Songsen; Ao Zhaohui; Liu Yuanyuan; Gao Naifei; Zheng Yuanming; Shong Liangquan

    1990-01-01

    The Moessbauer spectra have been measured in erythrocytes from normal adults and the patients with high altitude polycythemia (HAPC). The results indicated that two subspectra ''a'' and ''b'', corresponding to oxy- and deoxyhemoglobin respectively, were present in all blood samples, and a third subspectrum ''c'' was found to exist in almost all samples from the patients. The parameters of the third subspectra ''c1'' in most samples from the patients were similar to those of carbon monoxyhemoglobin. The components were considered to be the denatured hemoglobin in RBCs (red blood cells). Together with clinical analysis, a possible mechanism of HAPC has been discussed. (orig.)

  1. New Heights with High-Altitude Balloon Launches for Effective Student Learning and Environmental Awareness

    Science.gov (United States)

    Voss, H. D.; Dailey, J. F.; Takehara, D.; Krueger, J. M.

    2009-12-01

    Over a seven-year period Taylor University, an undergraduate liberal art school, has successfully launched and recovered over 200 sophisticated student payloads to altitudes between 20-33 km (100% success with rapid recovery) with flight times between 2 to 6 hrs. All of the payloads included two GPS tracking systems, cameras and monitors, a 110 kbit down link, an uplink command capability for educational experiments (K-12 and undergrad). Launches were conducted during the day and night, with multiple balloons, with up to 10 payloads for experiments, and under varying weather and upper atmospheric conditions. The many launches in a short period of time allowed the payload bus design to evolve toward increased performance, reliability, standardization, simplicity, and modularity for low-cost launch services. Through NSF and NASA grants, the program has expanded leading to over 50 universities trained at workshops to implement high altitude balloon launches in the classroom. A spin-off company (StraoStar Systems LLC) now sells the high-altitude balloon system and facilitates networking between schools. This high-altitude balloon program helps to advance knowledge and understanding across disciplines by giving students and faculty rapid and low-cost access to earth/ecology remote sensing from high altitude, insitu and limb atmospheric measurements, near-space stratosphere measurements, and IR/UV/cosmic ray access to the heavens. This new capability is possible by exposing students to recent advances in MEMS technology, nanotechnology, wireless telecommunication systems, GPS, DSPs and other microchip miniaturizations to build collaboration among science faculty, and provides quantitative assessment of the learning outcomes. Furthermore this program has generated many front page news reports along with significant TV coverage because of its connection to hands-on learning for students and adults of all ages, connection to understanding climate change and ways to mitigate

  2. The effect of α1 -adrenergic blockade on post-exercise brachial artery flow-mediated dilatation at sea level and high altitude.

    Science.gov (United States)

    Tymko, Michael M; Tremblay, Joshua C; Hansen, Alex B; Howe, Connor A; Willie, Chris K; Stembridge, Mike; Green, Daniel J; Hoiland, Ryan L; Subedi, Prajan; Anholm, James D; Ainslie, Philip N

    2017-03-01

    Our objective was to quantify endothelial function (via brachial artery flow-mediated dilatation) at sea level (344 m) and high altitude (3800 m) at rest and following both maximal exercise and 30 min of moderate-intensity cycling exercise with and without administration of an α 1 -adrenergic blockade. Brachial endothelial function did not differ between sea level and high altitude at rest, nor following maximal exercise. At sea level, endothelial function decreased following 30 min of moderate-intensity exercise, and this decrease was abolished with α 1 -adrenergic blockade. At high altitude, endothelial function did not decrease immediately after 30 min of moderate-intensity exercise, and administration of α 1 -adrenergic blockade resulted in an increase in flow-mediated dilatation. Our data indicate that post-exercise endothelial function is modified at high altitude (i.e. prolonged hypoxaemia). The current study helps to elucidate the physiological mechanisms associated with high-altitude acclimatization, and provides insight into the relationship between sympathetic nervous activity and vascular endothelial function. We examined the hypotheses that (1) at rest, endothelial function would be impaired at high altitude compared to sea level, (2) endothelial function would be reduced to a greater extent at sea level compared to high altitude after maximal exercise, and (3) reductions in endothelial function following moderate-intensity exercise at both sea level and high altitude are mediated via an α 1 -adrenergic pathway. In a double-blinded, counterbalanced, randomized and placebo-controlled design, nine healthy participants performed a maximal-exercise test, and two 30 min sessions of semi-recumbent cycling exercise at 50% peak output following either placebo or α 1 -adrenergic blockade (prazosin; 0.05 mg kg  -1 ). These experiments were completed at both sea-level (344 m) and high altitude (3800 m). Blood pressure (finger photoplethysmography

  3. Correlations between the simulated military tasks performance and physical fitness tests at high altitude

    Directory of Open Access Journals (Sweden)

    Eduardo Borba Neves

    2017-11-01

    Full Text Available The aim of this study was to investigate the Correlations between the Simulated Military Tasks Performance and Physical Fitness Tests at high altitude. This research is part of a project to modernize the physical fitness test of the Colombian Army. Data collection was performed at the 13th Battalion of Instruction and Training, located 30km south of Bogota D.C., with a temperature range from 1ºC to 23ºC during the study period, and at 3100m above sea level. The sample was composed by 60 volunteers from three different platoons. The volunteers start the data collection protocol after 2 weeks of acclimation at this altitude. The main results were the identification of a high positive correlation between the 3 Assault wall in succession and the Simulated Military Tasks performance (r = 0.764, p<0.001, and a moderate negative correlation between pull-ups and the Simulated Military Tasks performance (r = -0.535, p<0.001. It can be recommended the use of the 20-consecutive overtaking of the 3 Assault wall in succession as a good way to estimate the performance in operational tasks which involve: assault walls, network of wires, military Climbing Nets, Tarzan jump among others, at high altitude.

  4. Infrared observations of RS CVn stars

    Science.gov (United States)

    Berriman, G.; De Campli, W. M.; Werner, M. W.; Hatchett, S. P.

    1983-01-01

    The paper presents infrared photometry of the RS CVn binary stars AR Lac (1.2-10 microns) and MM Her (1.2-3.5 microns) as they egressed from their primary and secondary eclipses; of the eclipsing systems RS CVn and Z Her at maximum light (1.2-10 microns) and of the non-eclipsing systems UX Ari and HR 1099 (1.2-10 microns). An analysis of these and published V data based on flux ratio diagrams (linear analogues of color-color diagrams) shows that G and K stars supply the infrared light of these systems. In AR Lac, the combined light of a G5-K0 subgiant and either a late F dwarf or an early F subgiant can account for the observed visual and infrared light curves. None of these systems shows infrared emission from circumstellar matter. This result is simply understood: dust grains would not be expected to form in the physical conditions surrounding the subgiant, and the corona and chromosphere (whose properties have been deduced from spectroscopic X-ray observations) should not produce appreciable infrared emission.

  5. New interpretations of the Fort Clark State Historic Site based on aerial color and thermal infrared imagery

    Science.gov (United States)

    Heller, Andrew Roland

    The Fort Clark State Historic Site (32ME2) is a well known site on the upper Missouri River, North Dakota. The site was the location of two Euroamerican trading posts and a large Mandan-Arikara earthlodge village. In 2004, Dr. Kenneth L. Kvamme and Dr. Tommy Hailey surveyed the site using aerial color and thermal infrared imagery collected from a powered parachute. Individual images were stitched together into large image mosaics and registered to Wood's 1993 interpretive map of the site using Adobe Photoshop. The analysis of those image mosaics resulted in the identification of more than 1,500 archaeological features, including as many as 124 earthlodges.

  6. Search for bright stars with infrared excess

    Energy Technology Data Exchange (ETDEWEB)

    Raharto, Moedji, E-mail: moedji@as.itb.ac.id [Astronomy Research Division, Faculty of Mathematics and Natural Sciences, Institut Teknologi Bandung, Jl. Ganesha 10, Bandung 40132 (Indonesia)

    2014-03-24

    Bright stars, stars with visual magnitude smaller than 6.5, can be studied using small telescope. In general, if stars are assumed as black body radiator, then the color in infrared (IR) region is usually equal to zero. Infrared data from IRAS observations at 12 and 25μm (micron) with good flux quality are used to search for bright stars (from Bright Stars Catalogues) with infrared excess. In magnitude scale, stars with IR excess is defined as stars with IR color m{sub 12}−m{sub 25}>0; where m{sub 12}−m{sub 25} = −2.5log(F{sub 12}/F{sub 25})+1.56, where F{sub 12} and F{sub 25} are flux density in Jansky at 12 and 25μm, respectively. Stars with similar spectral type are expected to have similar color. The existence of infrared excess in the same spectral type indicates the existence of circum-stellar dust, the origin of which is probably due to the remnant of pre main-sequence evolution during star formation or post AGB evolution or due to physical process such as the rotation of those stars.

  7. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the North Bamyan mineral district in Afghanistan

    Science.gov (United States)

    Davis, Philip A.; Davis, Philip A.

    2013-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the North Bamyan mineral district, which has copper deposits. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420–500 nanometer, nm), green (520–600 nm), red (610–690 nm), and near-infrared (760–890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520–770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency (©JAXA,2006,2007, 2008), but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that original image values cannot be recreated from this DS. As such

  8. Local-area-enhanced, 2.5-meter resolution natural-color and color-infrared satellite-image mosaics of the South Bamyan mineral district in Afghanistan

    Science.gov (United States)

    Davis, Philip A.; Davis, Philip A.

    2013-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Department of Defense Task Force for Business and Stability Operations, prepared databases for mineral-resource target areas in Afghanistan. The purpose of the databases is to (1) provide useful data to ground-survey crews for use in performing detailed assessments of the areas and (2) provide useful information to private investors who are considering investment in a particular area for development of its natural resources. The set of satellite-image mosaics provided in this Data Series (DS) is one such database. Although airborne digital color-infrared imagery was acquired for parts of Afghanistan in 2006, the image data have radiometric variations that preclude their use in creating a consistent image mosaic for geologic analysis. Consequently, image mosaics were created using ALOS (Advanced Land Observation Satellite; renamed Daichi) satellite images, whose radiometry has been well determined (Saunier, 2007a,b). This part of the DS consists of the locally enhanced ALOS image mosaics for the South Bamyan mineral district, which has areas with a spectral reflectance anomaly that require field investigation. ALOS was launched on January 24, 2006, and provides multispectral images from the AVNIR (Advanced Visible and Near-Infrared Radiometer) sensor in blue (420–500 nanometer, nm), green (520–600 nm), red (610–690 nm), and near-infrared (760–890 nm) wavelength bands with an 8-bit dynamic range and a 10-meter (m) ground resolution. The satellite also provides a panchromatic band image from the PRISM (Panchromatic Remote-sensing Instrument for Stereo Mapping) sensor (520–770 nm) with the same dynamic range but a 2.5-m ground resolution. The image products in this DS incorporate copyrighted data provided by the Japan Aerospace Exploration Agency (©JAXA,2006,2007, 2008),but the image processing has altered the original pixel structure and all image values of the JAXA ALOS data, such that

  9. Station-keeping of a high-altitude balloon with electric propulsion and wireless power transmission: A concept study

    Science.gov (United States)

    van Wynsberghe, Erinn; Turak, Ayse

    2016-11-01

    A stable, ultra long-duration high-altitude balloon (HAB) platform which can maintain stationary position would represent a new paradigm for telecommunications and high-altitude observation and transmission services, with greatly reduced cost and complexity compared to existing technologies including satellites, telecom towers, and unmanned aerial vehicles (UAVs). This contribution proposes a lightweight superpressure balloon platform for deployment to an altitude of 25 km. Electrohydrodynamic (EHD) thrusters are presented to maintain position by overcoming stratospheric winds. Critical to maintaining position is a continual supply of electrical power to operate the on-board propulsion system. One viable solution is to deliver power wirelessly to a high-altitude craft from a ground-based transmitter. Microwave energy, not heavily attenuated by the atmosphere, can be provided remotely from a ground-based generator (magnetron, klystron, etc.) and steered electrically with an antenna array (phased array) at a designated frequency (such as 2.45 or 5.8 GHz). A rectifying antenna ("rectenna") on the bottom of the balloon converts waves into direct current for on-board use. Preliminary mission architecture, energy requirements, and safety concerns for a proposed system are presented along with recommended future work.

  10. High-altitude electromagnetic pulse environment over the lossy ground

    International Nuclear Information System (INIS)

    Xie Yanzhao; Wang Zanji

    2003-01-01

    The electromagnetic field above ground produced by an incident high-altitude electromagnetic pulse plane wave striking the ground plane was described in this paper in terms of the Fresnel reflection coefficients and the numerical FFT. The pulse reflected from the ground plane always cancel the incident field for the horizontal field component, but the reflected field adds to the incident for the vertical field component. The results of several cases for variations in the observation height, angle of incidence and lossy ground electrical parameters were also presented showing different e-field components above the earth

  11. Effects of high altitude training on exercise capacity: fact or myth.

    Science.gov (United States)

    de Paula, Paula; Niebauer, Josef

    2012-03-01

    High altitude training has become a mainstay in endurance sports, with live high-train low as the current protocol of choice. Athletes either live or sleep in artificial or natural hypoxic conditions with the aim to increase serum erythropoietin concentrations, which are thought to improve maximum oxygen uptake and thus exercise performance. Changes, however, are not very striking and only apparent in so-called responders, who are not a well-defined group and may be as little as 50% of the trained study population. Whereas some studies show minor improvement, others report no change or even worsening. Furthermore, the mechanisms behind the proposed beneficial changes remain obscure and are far from being proven. There is an evident lack of sufficiently powered randomized, double-blinded studies, with training protocols that are identical for all groups and groups that are indeed comparable. Several studies discriminate between responders and non-responders, without clearly assessing the characteristics of the so-called responders. Until this has been done, it remains unclear if such a group really exists and how these subjects are characterized. This, however, would be of immense value, so protocols could be tailored to athletes' needs. Taken together, the current literature on natural or artificial hypoxia somewhat documents improved performance at high but not low altitude.

  12. Application of altitude/hypoxic training by elite athletes.

    Science.gov (United States)

    Wilber, Randall L

    2007-09-01

    At the Olympic level, differences in performance are typically less than 0.5%. This helps explain why many contemporary elite endurance athletes in summer and winter sport incorporate some form of altitude/hypoxic training within their year-round training plan, believing that it will provide the "competitive edge" to succeed at the Olympic level. The purpose of this paper is to describe the practical application of altitude/hypoxic training as used by elite athletes. Within the general framework of the paper, both anecdotal and scientific evidence will be presented relative to the efficacy of several contemporary altitude/hypoxic training models and devices currently used by Olympic-level athletes for the purpose of legally enhancing performance. These include the three primary altitude/hypoxic training models: 1) live high+train high (LH+TH), 2) live high+train low (LH+TL), and 3) live low+train high (LL+TH). The LH+TL model will be examined in detail and will include its various modifications: natural/terrestrial altitude, simulated altitude via nitrogen dilution or oxygen filtration, and hypobaric normoxia via supplemental oxygen. A somewhat opposite approach to LH+TL is the altitude/hypoxic training strategy of LL+TH, and data regarding its efficacy will be presented. Recently, several of these altitude/hypoxic training strategies and devices underwent critical review by the World Anti-Doping Agency (WADA) for the purpose of potentially banning them as illegal performance-enhancing substances/methods. This paper will conclude with an update on the most recent statement from WADA regarding the use of simulated altitude devices.

  13. Endurance training at altitude.

    Science.gov (United States)

    Saunders, Philo U; Pyne, David B; Gore, Christopher J

    2009-01-01

    Since the 1968 Olympic Games when the effects of altitude on endurance performance became evident, moderate altitude training ( approximately 2000 to 3000 m) has become popular to improve competition performance both at altitude and sea level. When endurance athletes are exposed acutely to moderate altitude, a number of physiological responses occur that can comprise performance at altitude; these include increased ventilation, increased heart rate, decreased stroke volume, reduced plasma volume, and lower maximal aerobic power ((.)Vo(2max)) by approximately 15% to 20%. Over a period of several weeks, one primary acclimatization response is an increase in the volume of red blood cells and consequently of (.)Vo(2max). Altitudes > approximately 2000 m for >3 weeks and adequate iron stores are required to elicit these responses. However, the primacy of more red blood cells for superior sea-level performance is not clear-cut since the best endurance athletes in the world, from Ethiopia (approximately 2000 to 3000 m), have only marginally elevated hemoglobin concentrations. The substantial reduction in (.)Vo(2max) of athletes at moderate altitude implies that their training should include adequate short-duration (approximately 1 to 2 min), high-intensity efforts with long recoveries to avoid a reduction in race-specific fitness. At the elite level, athlete performance is not dependent solely on (.)Vo(2max), and the "smallest worthwhile change" in performance for improving race results is as little as 0.5%. Consequently, contemporary statistical approaches that utilize the concept of the smallest worthwhile change are likely to be more appropriate than conventional statistical methods when attempting to understand the potential benefits and mechanisms of altitude training.

  14. [Relationship between occupational stress and working ability of workers in a petroleum processing enterprise in high altitude area].

    Science.gov (United States)

    Ma, X M; Kang, H L; Shi, C B; Li, Y; Wu, Y F; Liu, Z H; Wang, G; Lei, H Y

    2017-12-20

    Objective: To investigate the relationship between occupational stress and working ability of workers in a petroleum processing enterprise in a high altitude area. Methods: A total of 728 workers in a petroleum processing enterprise at an altitude of 2850 m were subjected to a survey using Occupational Stress Inventory (OSI) , Work Ability Index (WAI) Scale, Occupational Role Questionnaire (ORQ) , Personal Strain Questionnaire (PSQ) , and Personal Resource Questionnaire (PRQ) from May 2014 to August 2016. Results: Of the 728 workers, 55 (7.6%) had a poor working ability, moderate in 262 (35.9%) , and good in 411 (56.5%). There were significant differences in WAI between the workers with different types of work, sexes, ages, and working years ( P occupational stress groups ( P Occupational stress is an influencing factor for the working ability of workers in the petroleum processing enterprise in the high altitude area. Hypoxia in high altitude area may further reduce the working ability. In order to reduce occupational stress and improve work ability, it should be considered to strengthen skills training, improve the working environment, and pay attention to mental health.

  15. High-visibility infrared beacons for IFF and combat ID

    Science.gov (United States)

    Pralle, Martin; Puscasu, Irina; Johnson, Edward; Loges, Peter; Melnyk, James

    2005-05-01

    A new kind of Identification Friend or Foe (IFF) infrared beacon has been demonstrated. The omni-directional beacon consists of a pyramidal array of 1W pulsIR thermal light sources. Operating at a total power of 84W, the beacon can be used to track and identify surface vehicles and personnel with a recognition range of up to 6 miles on the battlefield and in urban environments or the marine boundary layer. Advanced photonic technology enables the beacon to be seen only while using a 3-5 μm or 8-12 μm thermal imaging system. There is no visible or near-IR emission to betray the location of the beacon. The beacon is rugged and will operate from -40 to 50°C ambient temperature, 0-100% relative humidity, 0 - 10,000 ft altitude, and meets MIL-STD 810F and MIL-STD 461E.

  16. The differing magnitude distributions of the two Jupiter Trojan color populations

    Energy Technology Data Exchange (ETDEWEB)

    Wong, Ian; Brown, Michael E. [Division of Geological and Planetary Sciences, California Institute of Technology Pasadena, CA 91125 (United States); Emery, Joshua P., E-mail: iwong@caltech.edu [Department of Earth and Planetary Sciences, University of Tennessee Knoxville, TN 37996 (United States)

    2014-12-01

    The Jupiter Trojans are a significant population of minor bodies in the middle solar system that have garnered substantial interest in recent years. Several spectroscopic studies of these objects have revealed notable bimodalities with respect to near-infrared spectra, infrared albedo, and color, which suggest the existence of two distinct groups among the Trojan population. In this paper, we analyze the magnitude distributions of these two groups, which we refer to as the red and less red color populations. By compiling spectral and photometric data from several previous works, we show that the observed bimodalities are self-consistent and categorize 221 of the 842 Trojans with absolute magnitudes in the range H<12.3 into the two color populations. We demonstrate that the magnitude distributions of the two color populations are distinct to a high confidence level (>95%) and fit them individually to a broken power law, with special attention given to evaluating and correcting for incompleteness in the Trojan catalog as well as incompleteness in our categorization of objects. A comparison of the best-fit curves shows that the faint-end power-law slopes are markedly different for the two color populations, which indicates that the red and less red Trojans likely formed in different locations. We propose a few hypotheses for the origin and evolution of the Trojan population based on the analyzed data.

  17. Wilderness medicine at high altitude: recent developments in the field

    OpenAIRE

    Shah, Neeraj M; Hussain, Sidra; Cooke, Mark; O’Hara, John P; Mellor, Adrian

    2015-01-01

    Neeraj M Shah,1 Sidra Hussain,2 Mark Cooke,3 John P O’Hara,3 Adrian Mellor3,4 1Division of Asthma, Allergy and Lung Biology, King’s College London, UK; 2School of Medicine, University College London, London, UK; 3Research Institute for Sport, Physical Activity and Leisure, Leeds Beckett University, Leeds, UK; 4Academic Department of Military Anaesthesia and Critical Care, Royal Centre for Defence Medicine, Birmingham, UK Abstract: Travel to high altitude is increasingly p...

  18. Large high altitude air shower observatory (LHAASO) project

    International Nuclear Information System (INIS)

    He Huihai

    2010-01-01

    The Large High Altitude Air Shower Observatory (LHAASO) project focuses mainly on the study of 40 GeV-1 PeV gamma ray astronomy and 10 TeV-1 EeV cosmic ray physics. It consists of a 1 km 2 extensive air shower array with 40 000 m 2 muon detectors, 90,000m 2 water Cerenkov detector array, 5 000 m 2 shower core detector array and an air Cerenkov/fluorescence telescope array. Prototype detectors are designed with some of them already in operation. A prototype array of 1% size of LHAASO will be built at the Yangbajing Cosmic Ray Observatory and used to coincidently measure cosmic rays with the ARGO-YBJ experiment. (authors)

  19. Gamut mapping in a high-dynamic-range color space

    Science.gov (United States)

    Preiss, Jens; Fairchild, Mark D.; Ferwerda, James A.; Urban, Philipp

    2014-01-01

    In this paper, we present a novel approach of tone mapping as gamut mapping in a high-dynamic-range (HDR) color space. High- and low-dynamic-range (LDR) images as well as device gamut boundaries can simultaneously be represented within such a color space. This enables a unified transformation of the HDR image into the gamut of an output device (in this paper called HDR gamut mapping). An additional aim of this paper is to investigate the suitability of a specific HDR color space to serve as a working color space for the proposed HDR gamut mapping. For the HDR gamut mapping, we use a recent approach that iteratively minimizes an image-difference metric subject to in-gamut images. A psychophysical experiment on an HDR display shows that the standard reproduction workflow of two subsequent transformations - tone mapping and then gamut mapping - may be improved by HDR gamut mapping.

  20. High resolution color imagery for orthomaps and remote sensing

    Energy Technology Data Exchange (ETDEWEB)

    Fricker, Peter [Leica Geosystems GIS and Mapping, LLC (Switzerland); Gallo, M. Guillermo [Leica Geosystems GIS and Mapping, LLC (United States)

    2005-07-01

    The ADS40 Airborne Digital Pushbroom Sensor is currently the only commercial sensor capable of acquiring color and false color strip images in the low decimeter range at the same high resolution as the black and white stereo images. This high resolution of 12,000 pixels across the entire swath and 100% forward overlap in the image strips result in high quality DSM's, True Ortho's and at the same time allow unbiased remote sensing applications due to color strip images unchanged by pan-sharpening. The paper gives details on how the pushbroom sensor achieves these seemingly difficult technical challenges. It describes how a variety of mapping applications benefit from this sensor, a sensor which acts as a satellite pushbroom sensor within the airborne environment. (author)

  1. Radiation doses at high altitudes and during space flights

    International Nuclear Information System (INIS)

    Spurny, F.

    2001-01-01

    There are three main sources of radiation exposure during space flights and at high altitudes--galactic cosmic radiation, solar cosmic radiation and radiation of the earth's radiation belt. Their basic characteristics are presented in the first part of this paper.Man's exposure during space flights is discussed in the second part of the paper. Particular attention is devoted to the quantitative and qualitative characteristics of the radiation exposure on near-earth orbits: both theoretical estimation as well as experimental data are presented. Some remarks on radiation protection rules on-board space vehicles are also given.The problems connected with the radiation protection of air crew and passengers of subsonic and supersonic air transport are discussed in the last part of the paper. General characteristics of on-board radiation fields and their variations with flight altitude, geomagnetic parameters of a flight and the solar activity are presented, both based on theoretical estimates and experimental studies. The questions concerning air crew and passenger radiation protection arising after the publication of ICRP 60 recommendation are also discussed. Activities of different institutions relevant to the topic are mentioned; strategies to manage and check this type of radiation exposure are presented and discussed. Examples of results based on the author's personal experience are given, analyzed and discussed. (author)

  2. Reaching High Altitudes on Mars with an Inflatable Hypersonic Drag Balloon (Ballute)

    CERN Document Server

    Griebel, Hannes

    2010-01-01

    The concept of probing the atmosphere of planet Mars by means of a hypersonic drag balloon, a device known as a “ballute”, is a novel approach to planetary science. In this concept, the probe deploys an inflatable drag body out in space and may then enter the atmosphere either once or several times until it slowly descends towards the ground, taking continuous atmospheric and other readings across a large altitude and ground range. Hannes Griebel discusses the theory behind such a mission along with experience gained during its practical implementation, such as mission design, manufacturing, packing and deployment techniques as well as ground and flight tests. The author also studies other ballute applications, specifically emergency low Earth orbit recovery and delivering payloads to high altitude landing sites on Mars.

  3. Acute and Chronic Altitude-Induced Cognitive Dysfunction in Children and Adolescents.

    Science.gov (United States)

    Rimoldi, Stefano F; Rexhaj, Emrush; Duplain, Hervé; Urben, Sébastien; Billieux, Joël; Allemann, Yves; Romero, Catherine; Ayaviri, Alejandro; Salinas, Carlos; Villena, Mercedes; Scherrer, Urs; Sartori, Claudio

    2016-02-01

    To assess whether exposure to high altitude induces cognitive dysfunction in young healthy European children and adolescents during acute, short-term exposure to an altitude of 3450 m and in an age-matched European population permanently living at this altitude. We tested executive function (inhibition, shifting, and working memory), memory (verbal, short-term visuospatial, and verbal episodic memory), and speed processing ability in: (1) 48 healthy nonacclimatized European children and adolescents, 24 hours after arrival at high altitude and 3 months after return to low altitude; (2) 21 matched European subjects permanently living at high altitude; and (3) a matched control group tested twice at low altitude. Short-term hypoxia significantly impaired all but 2 (visuospatial memory and processing speed) of the neuropsychological abilities that were tested. These impairments were even more severe in the children permanently living at high altitude. Three months after return to low altitude, the neuropsychological performances significantly improved and were comparable with those observed in the control group tested only at low altitude. Acute short-term exposure to an altitude at which major tourist destinations are located induces marked executive and memory deficits in healthy children. These deficits are equally marked or more severe in children permanently living at high altitude and are expected to impair their learning abilities. Copyright © 2016 Elsevier Inc. All rights reserved.

  4. Protective effect of total flavonoids of seabuckthorn (Hippophae rhamnoides) in simulated high-altitude polycythemia in rats.

    Science.gov (United States)

    Zhou, Ji-Yin; Zhou, Shi-Wen; Du, Xiao-Huang; Zeng, Sheng-Ya

    2012-09-28

    Seabuckthorn (Hippophae rhamnoides L.) has been used to treat high altitude diseases. The effects of five-week treatment with total flavonoids of seabuckthorn (35, 70, 140 mg/kg, ig) on cobalt chloride (5.5 mg/kg, ip)- and hypobaric chamber (simulating 5,000 m)-induced high-altitude polycythemia in rats were measured. Total flavonoids decreased red blood cell number, hemoglobin, hematocrit, mean corpuscular hemoglobin levels, span of red blood cell electrophoretic mobility, aggregation index of red blood cell, plasma viscosity, whole blood viscosity, and increased deformation index of red blood cell, erythropoietin level in serum. Total flavonoids increased pH, pO₂, Sp(O₂), pCO₂ levels in arterial blood, and increased Na⁺, HCO₃⁻, Cl⁻, but decreased K⁺ concentrations. Total flavonoids increased mean arterial pressure, left ventricular systolic pressure, end-diastolic pressure, maximal rate of rise and decrease, decreased heart rate and protected right ventricle morphology. Changes in hemodynamic, hematologic parameters, and erythropoietin content suggest that administration of total flavonoids from seabuckthorn may be useful in the prevention of high altitude polycythaemia in rats.

  5. Altitude and endurance training.

    Science.gov (United States)

    Rusko, Heikki K; Tikkanen, Heikki O; Peltonen, Juha E

    2004-10-01

    The benefits of living and training at altitude (HiHi) for an improved altitude performance of athletes are clear, but controlled studies for an improved sea-level performance are controversial. The reasons for not having a positive effect of HiHi include: (1) the acclimatization effect may have been insufficient for elite athletes to stimulate an increase in red cell mass/haemoglobin mass because of too low an altitude (altitude training period (training effect at altitude may have been compromised due to insufficient training stimuli for enhancing the function of the neuromuscular and cardiovascular systems; and (3) enhanced stress with possible overtraining symptoms and an increased frequency of infections. Moreover, the effects of hypoxia in the brain may influence both training intensity and physiological responses during training at altitude. Thus, interrupting hypoxic exposure by training in normoxia may be a key factor in avoiding or minimizing the noxious effects that are known to occur in chronic hypoxia. When comparing HiHi and HiLo (living high and training low), it is obvious that both can induce a positive acclimatization effect and increase the oxygen transport capacity of blood, at least in 'responders', if certain prerequisites are met. The minimum dose to attain a haematological acclimatization effect is > 12 h a day for at least 3 weeks at an altitude or simulated altitude of 2100-2500 m. Exposure to hypoxia appears to have some positive transfer effects on subsequent training in normoxia during and after HiLo. The increased oxygen transport capacity of blood allows training at higher intensity during and after HiLo in subsequent normoxia, thereby increasing the potential to improve some neuromuscular and cardiovascular determinants of endurance performance. The effects of hypoxic training and intermittent short-term severe hypoxia at rest are not yet clear and they require further study.

  6. Space Based Infrared System High (SBIRS High)

    Science.gov (United States)

    2015-12-01

    elements (five SMGTs) for the S2E2 Mobile Ground System. ​ SBIRS Block Buy (GEO 5-6) The GEO 5-6 Tech Refresh (TR) Engineering Change Proposal was...Selected Acquisition Report (SAR) RCS: DD-A&T(Q&A)823-210 Space Based Infrared System High ( SBIRS High) As of FY 2017 President’s Budget Defense...Acquisition Management Information Retrieval (DAMIR) March 23, 2016 11:24:26 UNCLASSIFIED SBIRS High December 2015 SAR March 23, 2016 11:24:26

  7. Event-Based Color Segmentation With a High Dynamic Range Sensor

    Directory of Open Access Journals (Sweden)

    Alexandre Marcireau

    2018-04-01

    Full Text Available This paper introduces a color asynchronous neuromorphic event-based camera and a methodology to process color output from the device to perform color segmentation and tracking at the native temporal resolution of the sensor (down to one microsecond. Our color vision sensor prototype is a combination of three Asynchronous Time-based Image Sensors, sensitive to absolute color information. We devise a color processing algorithm leveraging this information. It is designed to be computationally cheap, thus showing how low level processing benefits from asynchronous acquisition and high temporal resolution data. The resulting color segmentation and tracking performance is assessed both with an indoor controlled scene and two outdoor uncontrolled scenes. The tracking's mean error to the ground truth for the objects of the outdoor scenes ranges from two to twenty pixels.

  8. A New Infrared Color Criterion for the Selection of 0 < z < 7 AGNs: Application to Deep Fields and Implications for JWST Surveys

    Science.gov (United States)

    Messias, H.; Afonso, J.; Salvato, M.; Mobasher, B.; Hopkins, A. M.

    2012-08-01

    It is widely accepted that observations at mid-infrared (mid-IR) wavelengths enable the selection of galaxies with nuclear activity, which may not be revealed even in the deepest X-ray surveys. Many mid-IR color-color criteria have been explored to accomplish this goal and tested thoroughly in the literature. Besides missing many low-luminosity active galactic nuclei (AGNs), one of the main conclusions is that, with increasing redshift, the contamination by non-active galaxies becomes significant (especially at z >~ 2.5). This is problematic for the study of the AGN phenomenon in the early universe, the main goal of many of the current and future deep extragalactic surveys. In this work new near- and mid-IR color diagnostics are explored, aiming for improved efficiency—better completeness and less contamination—in selecting AGNs out to very high redshifts. We restrict our study to the James Webb Space Telescope wavelength range (0.6-27 μm). The criteria are created based on the predictions by state-of-the-art galaxy and AGN templates covering a wide variety of galaxy properties, and tested against control samples with deep multi-wavelength coverage (ranging from the X-rays to radio frequencies). We show that the colors Ks - [4.5], [4.5] - [8.0], and [8.0] - [24] are ideal as AGN/non-AGN diagnostics at, respectively, z ~ 2.5-3. However, when the source redshift is unknown, these colors should be combined. We thus develop an improved IR criterion (using Ks and IRAC bands, KI) as a new alternative at z 50%-90% level of successful AGN selection). We also propose KIM (using Ks , IRAC, and MIPS 24 μm bands, KIM), which aims to select AGN hosts from local distances to as far back as the end of reionization (0 ~ 2.5. Overall, KIM shows a ~30%-40% completeness and a >70%-90% level of successful AGN selection. KI and KIM are built to be reliable against a ~10%-20% error in flux, are based on existing filters, and are suitable for immediate use.

  9. Agroforestry systems, nutrients in litter and microbial activity in soils cultivated with coffee at high altitude

    Directory of Open Access Journals (Sweden)

    Krystal de Alcantara Notaro

    2014-04-01

    Full Text Available Agroforestry systems are an alternative option for sustainable production management. These systems contain trees that absorb nutrients from deeper layers of the soil and leaf litter that help improve the soil quality of the rough terrain in high altitude areas, which are areas extremely susceptible to environmental degradation. The aim of this study was to characterize the stock and nutrients in litter, soil activity and the population of microorganisms in coffee (Coffea arabica L. plantations under high altitude agroforestry systems in the semi-arid region of the state of Pernambuco, Brazil. Samples were collected from the surface litter together with soil samples taken at two depths (0-10 and 10-20 cm from areas each subject to one of the following four treatments: agroforestry system (AS, native forest (NF, biodynamic system (BS and coffee control (CT.The coffee plantation had been abandoned for nearly 15 years and, although there had been no management or harvesting, still contained productive coffee plants. The accumulation of litter and mean nutrient content of the litter, the soil nutrient content, microbial biomass carbon, total carbon, total nitrogen, C/N ratio, basal respiration, microbial quotient, metabolic quotient and microbial populations (total bacteria, fluorescent bacteria group, total fungi and Trichoderma spp. were all analyzed. The systems thatwere exposed to human intervention (A and BS differed in their chemical attributes and contained higher levels of nutrients when compared to NF and CT. BS for coffee production at high altitude can be used as a sustainable alternative in the high altitude zones of the semi-arid region in Brazil, which is an area that is highly susceptible to environmental degradation.

  10. Performance changes during a weeklong high-altitude alpine ski-racing training camp in lowlander young athletes.

    Science.gov (United States)

    Hydren, Jay R; Kraemer, William J; Volek, Jeff S; Dunn-Lewis, Courtenay; Comstock, Brett A; Szivak, Tunde K; Hooper, David R; Denegar, Craig R; Maresh, Carl M

    2013-04-01

    Thousands of youth athletes travel to high altitude to participate in lift-access alpine sports. The purpose of this study was to examine the impact of acute high-altitude exposure on balance, choice reaction time, power, quickness, flexibility, strength endurance, and V[Combining Dot Above]O2max in youth lowlander athletes during a weeklong preseason training camp in Summit County, CO, USA. Eleven youth ski racers (4 boys and 7 girls; age, 13.7 ± 0.5 years; height, 157.2 ± 12.6 cm; weight, 52.4 ± 6.8 kg) with 7.7 ± 2.2 skiing years of experience participated in baseline testing at 160 m one week before the camp and a set of daily tests in the morning and afternoon at 2,828 m and skied between 3,328 and 3,802 m during a 6-day camp. Balance and choice reaction time tests were stagnant or improved slightly during the first 3 days and then improved on days 4 and 6. Vertical jump, flexibility, T-agility test, and push-ups in 1 minute improved on day 6. The number of sit-ups in 1 minute did not improve, and scores on the multistage fitness test decreased 20.34%. There was no effect of Lake Louise acute mountain sickness (AMS) questionnaire scores on performance variables measured. Athletes sojourning to high altitude for ski camps can train on immediate ascent but should slowly increase training volume over the first 3 days. Athletes should expect improvements in balance and reaction time 3-6 days into acclimatization. Coaches and athletes should expect about 20% of youth lowlander athletes to have signs and symptoms of AMS during the first 3 days of altitude exposure for alpine lift access sports at altitudes of up to 3,800 m.

  11. Factors associated with poor balance ability in older adults of nine high-altitude communities.

    Science.gov (United States)

    Urrunaga-Pastor, Diego; Moncada-Mapelli, Enrique; Runzer-Colmenares, Fernando M; Bailon-Valdez, Zaira; Samper-Ternent, Rafael; Rodriguez-Mañas, Leocadio; Parodi, Jose F

    2018-05-01

    Poor balance ability in older adults result in multiple complications. Poor balance ability has not been studied among older adults living at high altitudes. In this study, we analysed factors associated with poor balance ability by using the Functional Reach (FR) among older adults living in nine high-altitude communities. Analytical cross-sectional study, carried out in inhabitants aged 60 or over from nine high-altitude Andean communities of Peru during 2013-2016. FR was divided according to the cut-off point of 8 inches (20.32 cm) and two groups were generated: poor balance ability (FR less or equal than 20.32 cm) and good balance ability (greater than 20.32 cm). Additionally, we collected socio-demographic, medical, functional and cognitive assessment information. Poisson regression models were constructed to identify factors associated with poor balance ability. Prevalence ratio (PR) with 95% confidence intervals (95CI%) are presented. A total of 365 older adults were studied. The average age was 73.0 ± 6.9 years (range: 60-91 years), and 180 (49.3%) participants had poor balance ability. In the adjusted Poisson regression analysis, the factors associated with poor balance ability were: alcohol consumption (PR = 1.35; 95%CI: 1.05-1.73), exhaustion (PR = 2.22; 95%CI: 1.49-3.31), gait speed (PR = 0.67; 95%CI: 0.50-0.90), having had at least one fall in the last year (PR = 2.03; 95%CI: 1.19-3.46), having at least one comorbidity (PR = 1.60; 95%CI: 1.10-2.35) and having two or more comorbidities (PR = 1.61; 95%CI: 1.07-2.42) compared to none. Approximately a half of the older adults from these high-altitude communities had poor balance ability. Interventions need to be designed to target these balance issues and prevent adverse events from concurring to these individuals. Copyright © 2018 Elsevier B.V. All rights reserved.

  12. Reducing pulmonary injury by hyperbaric oxygen preconditioning during simulated high altitude exposure in rats.

    Science.gov (United States)

    Li, Zhuo; Gao, Chunjin; Wang, Yanxue; Liu, Fujia; Ma, Linlin; Deng, Changlei; Niu, Ko-Chi; Lin, Mao-Tsun; Wang, Chen

    2011-09-01

    Hyperbaric oxygen preconditioning (HBO₂P + HAE) has been found to be beneficial in preventing the occurrence of ischemic damage to brain, spinal cord, heart, and liver in several disease models. In addition, pulmonary inflammation and edema are associated with a marked reduction in the expression levels of both aquaporin (AQP) 1 and AQP5 in the lung. Here, the aims of this study are first to ascertain whether acute lung injury can be induced by simulated high altitude in rats and second to assess whether HBO2P + HAE is able to prevent the occurrence of the proposed high altitude-induced ALI. Rats were randomly divided into the following three groups: the normobaric air (NBA; 21% O₂ at 1 ATA) group, the HBO₂P + high altitude exposure (HAE) group, and the NBA + HAE group. In HBO₂P + HAE group, animals received 100% O₂ at 2.0 ATA for 1 hour per day, for five consecutive days. In HAE groups, animals were exposed to a simulated HAE of 6,000 m in a hypobaric chamber for 24 hours. Right after being taken out to the ambient, animals were anesthetized generally and killed and thoroughly exsanguinated before their lungs were excised en bloc. The lungs were used for both histologic and molecular evaluation and analysis. In NBA + HAE group, the animals displayed higher scores of alveolar edema, neutrophil infiltration, and hemorrhage compared with those of NBA controls. In contrast, the levels of both AQP1 and AQP5 proteins and mRNA expression in the lung in the NBA + HAE group were significantly lower than those of NBA controls. However, the increased lung injury scores and the decreased levels of both AQP1 and AQP5 proteins and mRNA expression in the lung caused by HAE was significantly reduced by HBO₂P + HAE. Our results suggest that high altitude pulmonary injury may be prevented by HBO2P + HAE in rats.

  13. High-speed high-sensitivity infrared spectroscopy using mid-infrared swept lasers (Conference Presentation)

    Science.gov (United States)

    Childs, David T. D.; Groom, Kristian M.; Hogg, Richard A.; Revin, Dmitry G.; Cockburn, John W.; Rehman, Ihtesham U.; Matcher, Stephen J.

    2016-03-01

    Infrared spectroscopy is a highly attractive read-out technology for compositional analysis of biomedical specimens because of its unique combination of high molecular sensitivity without the need for exogenous labels. Traditional techniques such as FTIR and Raman have suffered from comparatively low speed and sensitivity however recent innovations are challenging this situation. Direct mid-IR spectroscopy is being speeded up by innovations such as MEMS-based FTIR instruments with very high mirror speeds and supercontinuum sources producing very high sample irradiation levels. Here we explore another possible method - external cavity quantum cascade lasers (EC-QCL's) with high cavity tuning speeds (mid-IR swept lasers). Swept lasers have been heavily developed in the near-infrared where they are used for non-destructive low-coherence imaging (OCT). We adapt these concepts in two ways. Firstly by combining mid-IR quantum cascade gain chips with external cavity designs adapted from OCT we achieve spectral acquisition rates approaching 1 kHz and demonstrate potential to reach 100 kHz. Secondly we show that mid-IR swept lasers share a fundamental sensitivity advantage with near-IR OCT swept lasers. This makes them potentially able to achieve the same spectral SNR as an FTIR instrument in a time x N shorter (N being the number of spectral points) under otherwise matched conditions. This effect is demonstrated using measurements of a PDMS sample. The combination of potentially very high spectral acquisition rates, fundamental SNR advantage and the use of low-cost detector systems could make mid-IR swept lasers a powerful technology for high-throughput biomedical spectroscopy.

  14. The effect of α1‐adrenergic blockade on post‐exercise brachial artery flow‐mediated dilatation at sea level and high altitude

    Science.gov (United States)

    Tremblay, Joshua C.; Hansen, Alex B.; Howe, Connor A.; Willie, Chris K.; Stembridge, Mike; Green, Daniel J.; Hoiland, Ryan L.; Subedi, Prajan; Anholm, James D.; Ainslie, Philip N.

    2016-01-01

    Key points Our objective was to quantify endothelial function (via brachial artery flow‐mediated dilatation) at sea level (344 m) and high altitude (3800 m) at rest and following both maximal exercise and 30 min of moderate‐intensity cycling exercise with and without administration of an α1‐adrenergic blockade.Brachial endothelial function did not differ between sea level and high altitude at rest, nor following maximal exercise.At sea level, endothelial function decreased following 30 min of moderate‐intensity exercise, and this decrease was abolished with α1‐adrenergic blockade. At high altitude, endothelial function did not decrease immediately after 30 min of moderate‐intensity exercise, and administration of α1‐adrenergic blockade resulted in an increase in flow‐mediated dilatation.Our data indicate that post‐exercise endothelial function is modified at high altitude (i.e. prolonged hypoxaemia). The current study helps to elucidate the physiological mechanisms associated with high‐altitude acclimatization, and provides insight into the relationship between sympathetic nervous activity and vascular endothelial function. Abstract We examined the hypotheses that (1) at rest, endothelial function would be impaired at high altitude compared to sea level, (2) endothelial function would be reduced to a greater extent at sea level compared to high altitude after maximal exercise, and (3) reductions in endothelial function following moderate‐intensity exercise at both sea level and high altitude are mediated via an α1‐adrenergic pathway. In a double‐blinded, counterbalanced, randomized and placebo‐controlled design, nine healthy participants performed a maximal‐exercise test, and two 30 min sessions of semi‐recumbent cycling exercise at 50% peak output following either placebo or α1‐adrenergic blockade (prazosin; 0.05 mg kg −1). These experiments were completed at both sea‐level (344 m) and high altitude (3800

  15. Changes in labial capillary density on ascent to and descent from high altitude [version 1; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Edward Gilbert-Kawai

    2016-08-01

    Full Text Available Present knowledge of how the microcirculation is altered by prolonged exposure to hypoxia at high altitude is incomplete and modification of existing analytical techniques may improve our knowledge considerably. We set out to use a novel simplified method of measuring in vivo capillary density during an expedition to high altitude using a CytoCam incident dark field imaging video-microscope. The simplified method of data capture involved recording one-second images of the mucosal surface of the inner lip to reveal data about microvasculature density in ten individuals. This was done on ascent to, and descent from, high altitude. Analysis was conducted offline by two independent investigators blinded to the participant identity, testing conditions and the imaging site.  Additionally we monitored haemoglobin concentration and haematocrit data to see if we could support or refute mechanisms of altered density relating to vessel recruitment. Repeated sets of paired values were compared using Kruskall Wallis Analysis of Variance tests, whilst comparisons of values between sites was by related samples Wilcoxon Signed Rank Test. Correlation between different variables was performed using Spearman’s rank correlation coefficient, and concordance between analysing investigators using intra-class correlation coefficient. There was a significant increase in capillary density from London on ascent to high altitude; median capillaries per field of view area increased from 22.8 to 25.3 (p=0.021. There was a further increase in vessel density during the six weeks spent at altitude (25.3 to 32.5, p=0.017. Moreover, vessel density remained high on descent to Kathmandu (31.0 capillaries per field of view area, despite a significant decrease in haemoglobin concentration and haematocrit. Using a simplified technique, we have demonstrated an increase in capillary density on early and sustained exposure to hypobaric hypoxia at thigh altitude, and that this remains

  16. NeuroSeek dual-color image processing infrared focal plane array

    Science.gov (United States)

    McCarley, Paul L.; Massie, Mark A.; Baxter, Christopher R.; Huynh, Buu L.

    1998-09-01

    Several technologies have been developed in recent years to advance the state of the art of IR sensor systems including dual color affordable focal planes, on-focal plane array biologically inspired image and signal processing techniques and spectral sensing techniques. Pacific Advanced Technology (PAT) and the Air Force Research Lab Munitions Directorate have developed a system which incorporates the best of these capabilities into a single device. The 'NeuroSeek' device integrates these technologies into an IR focal plane array (FPA) which combines multicolor Midwave IR/Longwave IR radiometric response with on-focal plane 'smart' neuromorphic analog image processing. The readout and processing integrated circuit very large scale integration chip which was developed under this effort will be hybridized to a dual color detector array to produce the NeuroSeek FPA, which will have the capability to fuse multiple pixel-based sensor inputs directly on the focal plane. Great advantages are afforded by application of massively parallel processing algorithms to image data in the analog domain; the high speed and low power consumption of this device mimic operations performed in the human retina.

  17. VT Data - VTORTHO Color Imagery (0.15m) 2017, Addison County

    Data.gov (United States)

    Vermont Center for Geographic Information — (Link to Metadata) This metadata record describes the acquisition and production of 15 centimeter ground sample distance (GSD) natural color and color infrared...

  18. Effects of High Altitude on Sleep and Respiratory System and Theirs Adaptations

    Directory of Open Access Journals (Sweden)

    Turhan San

    2013-01-01

    Full Text Available High-altitude (HA environments have adverse effects on the normal functioning body of people accustomed to living at low altitudes because of the change in barometric pressure which causes decrease in the amount of oxygen leading to hypobaric hypoxia. Sustained exposure to hypoxia has adverse effects on body weight, muscle structure and exercise capacity, mental functioning, and sleep quality. The most important step of acclimatization is the hyperventilation which is achieved by hypoxic ventilatory response of the peripheral chemoreceptors. Hyperventilation results in increase in arterial carbondioxide concentration. Altitude also affects sleep and cardiac output, which is the other determinant of oxygen delivery. Upon initial exposure to HA, the resting pulse rate increases rapidly, but with acclimatization, heart rate and cardiac output tend to fall. Another important component that leads to decrease in cardiac output is the reduction in the stroke volume with acclimatization. During sleep at HA, the levels of CO2 in the blood can drop very low and this can switch off the drive to breathe. Only after the body senses a further drop in O2 levels breathing is started again. Periodic breathing is thought to result from instability in the control system through the hypoxic drive or the response to CO2.

  19. NEAR-INFRARED LINEAR POLARIZATION OF ULTRACOOL DWARFS

    International Nuclear Information System (INIS)

    Zapatero Osorio, M. R.; Bejar, V. J. S.; Rebolo, R.; Acosta-Pulido, J. A.; Manchado, A.; Pena Ramirez, K.; Goldman, B.; Caballero, J. A.

    2011-01-01

    We report on near-infrared J- and H-band linear polarimetric photometry of eight ultracool dwarfs (two late-M, five L0-L7.5, and one T2.5) with known evidence for photometric variability due to dust clouds, anomalous red infrared colors, or low-gravity atmospheres. The polarimetric data were acquired with the LIRIS instrument on the William Herschel Telescope. We also provide mid-infrared photometry in the interval 3.4-24 μm for some targets obtained with Spitzer and WISE, which has allowed us to confirm the peculiar red colors of five sources in the sample. We can impose modest upper limits of 0.9% and 1.8% on the linear polarization degree for seven targets with a confidence of 99%. Only one source, 2MASS J02411151-0326587 (L0), appears to be strongly polarized (P ∼ 3%) in the J band with a significance level of P/σ P ∼ 10. The likely origin of its linearly polarized light and rather red infrared colors may reside in a surrounding disk with an asymmetric distribution of grains. Given its proximity (66 ± 8 pc), this object becomes an excellent target for the direct detection of the disk.

  20. The Vortex Formerly Known as White Oval BA: Temperature Structure, CloudProperties and Dynamical Simulation

    Science.gov (United States)

    Orton, Glenn S.; Yanamandra-Fisher, P. A.; Parrish, P. D.; Mousis, O.; Pantin, E.; Fuse, T.; Fujiyoshi, T.; Simon-Miller, A.; Morales-Juberias, R.; Tollestrup, E.; Connelley, M.; Trujillo, C.; Hora, J.; Irwin, P.; Fletcher, L.; Hill, D.; Kollmansberger, S.

    2006-09-01

    White Oval BA, constituted from 3 predecessor vortices (known as Jupiter's "classical" White Ovals) after successive mergers in 1998 and 2000, became second-largest vortex in the atmosphere of Jupiter (and possibly the solar system) at the time of its formation. While it continues in this distinction,it required a name change after a 2005 December through 2006 February transformation which made it appear visually the same color as the Great Red Spot. Our campaign to understand the changes involved examination of the detailed color and wind field using Hubble Space Telescope instrumentation on several orbits in April. The field of temperatures, ammonia distribution and clouds were also examined using the mid-infrared VISIR camera/spectrometer on ESO's 8.2-m Very Large Telescope, the NASA Infrared telescope with the mid-infrared MIRSI instrument and the refurbished near-infrared facility camera NSFCam2. High-resolution images of the Oval were made before the color change with the COMICS mid-infrared facility on the 8.2-m Subaru telescope.We are using these images, togther with images acquired at the IRTF and with the Gemini/North NIRI near-infrared camera between January, 2005, and August, 2006, to characterize the extent to which changes in storm strength (vorticity, postive vertical motion) influenced (i) the depth from which colored cloud particles may have been "dredged up" from depth or (ii) the altitude to which particles may have been lofted and subject to high-energy UV radiation which caused a color change, as alternative explanations for the phenomenon. Clues to this will provide clues to the chemistry of Jupiter's cloud system and its well-known colors in general. The behavior of Oval BA, its interaction with the Great Red Spot in particular,are also being compared with dynamical models run with the EPIC code.

  1. Grappling the High Altitude for Safe Edible Bamboo Shoots with Rich Nutritional Attributes and Escaping Cyanogenic Toxicity

    Directory of Open Access Journals (Sweden)

    Sayanika Devi Waikhom

    2013-01-01

    Full Text Available Consumption of bamboo species with high level of total cyanogenic content (TCC in Asia by many ethnic groups is significantly associated with food poisoning and occasionally Konzo (a neurological disorder. Adequate characterization of edible bamboo species with low level of TCC and high nutritious attributes is required for consumer’s safety as well as for the conservation of the gene pool. Here, we employed morphological descriptors, atomic absorption spectrophotometer, RAPD, and trnL-F intergenic spacer to characterize 15 indigenous edible bamboo species of north-east India. The study indicates that morphologically and genetically evolved edible bamboo species having large and robust bamboo-shoot texture and growing at low altitude contain high level of TCC, low antioxidant properties, and low levels of beneficial macronutrients and micronutrients. Importantly, Dendrocalamus species are shown to be rich in TCC irrespective of the growing altitude while Bambusa species are found to have moderate level of TCC. The findings clearly demonstrated that Chimonobambusa callosa growing at high altitude represents safe edible bamboo species with nutritious attributes.

  2. Imaging Findings of a Survivor of Avalanche without Any Life Support at Very High Altitude and Extreme Low Temperatures

    Directory of Open Access Journals (Sweden)

    Abhishek Dwivedi

    2016-10-01

    Full Text Available Survival at high altitude is very challenging and in spite of adequate training and acclimatization, injuries are frequent. The fate of mountaineers and soldiers at such areas largely depends on the mercy of the climate. An avalanche causes physical trauma, cold injury and asphyxia to the victim. The patient in our report had diffuse cerebral edema, bilateral pulmonary consolidation and pneumothorax. In spite of the best efforts the victim succumbed to the injuries. There are many incidents of high altitude accidents in India. This case report is of a soldier deployed at the high altitude, is a lone ever reported survivor above 5000 meters, under 35 feet snow and below - 45°C for greater than 5 days of exposure to an avalanche

  3. Exercise and Training at Altitudes: Physiological Effects and Protocols

    Directory of Open Access Journals (Sweden)

    Olga Cecilia Vargas Pinilla

    2014-01-01

    Full Text Available An increase in altitude leads to a proportional fall in the barometric pressure, and a decrease in atmospheric oxygen pressure, producing hypobaric hypoxia that affects, in different degrees, all body organs, systems and functions. The chronically reduced partial pressure of oxygen causes that individuals adapt and adjust to physiological stress. These adaptations are modulated by many factors, including the degree of hypoxia related to altitude, time of exposure, exercise intensity and individual conditions. It has been established that exposure to high altitude is an environmental stressor that elicits a response that contributes to many adjustments and adaptations that influence exercise capacity and endurance performance. These adaptations include in crease in hemoglobin concentration, ventilation, capillary density and tissue myoglobin concentration. However, a negative effect in strength and power is related to a decrease in muscle fiber size and body mass due to the decrease in the training intensity. Many researches aim at establishing how training or living at high altitudes affects performance in athletes. Training methods, such as living in high altitudes training low, and training high-living in low altitudes have been used to research the changes in the physical condition in athletes and how the physiological adaptations to hypoxia can enhanceperformance at sea level. This review analyzes the literature related to altitude training focused on how physiological adaptations to hypoxic environments influence performance, and which protocols are most frequently used to train in high altitudes.

  4. Excessive Iron Availability Caused by Disorders of Interleukin-10 and Interleukin-22 Contributes to High Altitude Polycythemia

    Directory of Open Access Journals (Sweden)

    Yun-Sheng Liu

    2018-05-01

    Full Text Available Background: Because the pathogenesis of high altitude polycythemia (HAPC is unclear, the aim of the present study was to explore whether abnormal iron metabolism is involved in the pathogenesis of HAPC and the possible cause.Methods: We examined the serum levels of iron, total iron binding capacity, soluble transferrin receptor (sTfR, ferritin, and hepcidin as well as erythropoietin (EPO and inflammation-related cytokines in 20 healthy volunteers at sea level, 36 healthy high-altitude migrants, and 33 patients with HAPC. Mice that were exposed to a simulated hypoxic environment at an altitude of 5,000 m for 4 weeks received exogenous iron or intervention on cytokines, and the iron-related and hematological indices of peripheral blood and bone marrow were detected. The in vitro effects of some cytokines on hematopoietic cells were also observed.Results: Iron mobilization and utilization were enhanced in people who had lived at high altitudes for a long time. Notably, both the iron storage in ferritin and the available iron in the blood were elevated in patients with HAPC compared with the healthy high-altitude migrants. The correlation analysis indicated that the decreased hepcidin may have contributed to enhanced iron availability in HAPC, and decreased interleukin (IL-10 and IL-22 were significantly associated with decreased hepcidin. The results of the animal experiments confirmed that a certain degree of iron redundancy may promote bone marrow erythropoiesis and peripheral red blood cell production in hypoxic mice and that decreased IL-10 and IL-22 stimulated iron mobilization during hypoxia by affecting hepcidin expression.Conclusion: These data demonstrated, for the first time, that an excess of obtainable iron caused by disordered IL-10 and IL-22 was involved in the pathogenesis of some HAPC patients. The potential benefits of iron removal and immunoregulation for the prevention and treatment of HAPC deserve further research.

  5. Altitude training considerations for the winter sport athlete.

    Science.gov (United States)

    Chapman, Robert F; Stickford, Jonathon L; Levine, Benjamin D

    2010-03-01

    Winter sports events routinely take place at low to moderate altitudes, and nearly all Winter Olympic Games have had at least one venue at an altitude >1000 m. The acute and chronic effects of altitude can have a substantial effect on performance outcomes. Acutely, the decline in oxygen delivery to working muscle decreases maximal oxygen uptake, negatively affecting performance in endurance events, such as cross-country skiing and biathlon. The reduction in air resistance at altitude can dramatically affect sports involving high velocities and technical skill components, such as ski jumping, speed skating, figure skating and ice hockey. Dissociation between velocity and sensations usually associated with work intensity (ventilation, metabolic signals in skeletal muscle and heart rate) may impair pacing strategy and make it difficult to determine optimal race pace. For competitions taking place at altitude, a number of strategies may be useful, depending on the altitude of residence of the athlete and ultimate competition altitude, as follows. First, allow extra time and practice (how much is yet undetermined) for athletes to adjust to the changes in projectile motion; hockey, shooting, figure skating and ski jumping may be particularly affected. These considerations apply equally in the reverse direction; that is, for athletes practising at altitude but competing at sea level. Second, allow time for acclimatization for endurance sports: 3-5 days if possible, especially for low altitude (500-2000 m); 1-2 weeks for moderate altitude (2000-3000 m); and at least 2 weeks if possible for high altitude (>3000 m). Third, increase exercise-recovery ratios as much as possible, with 1:3 ratio probably optimal, and consider more frequent substitutions for sports where this is allowed, such as ice hockey. Fourth, consider the use of supplemental O(2) on the sideline (ice hockey) or in between heats (skating and Alpine skiing) to facilitate recovery. For competitions at sea

  6. Surname-inferred Andean ancestry is associated with child stature and limb lengths at high altitude in Peru, but not at sea level.

    Science.gov (United States)

    Pomeroy, Emma; Wells, Jonathan C K; Stanojevic, Sanja; Miranda, J Jaime; Moore, Lorna G; Cole, Tim J; Stock, Jay T

    2015-01-01

    Native Andean ancestry gives partial protection from reduced birthweight at high altitude in the Andes compared with European ancestry. Whether Andean ancestry is also associated with body proportions and greater postnatal body size at altitude is unknown. Therefore, we tested whether a greater proportion of Andean ancestry is associated with stature and body proportions among Peruvian children at high and low altitude. Height, head circumference, head-trunk height, upper and lower limb lengths, and tibia, ulna, hand and foot lengths, were measured in 133 highland and 169 lowland children aged 6 months to 8.5 years. For highland and lowland groups separately, age-sex-adjusted anthropometry z scores were regressed on the number of indigenous parental surnames as a proxy for Andean ancestry, adjusting for potential confounders (maternal age and education, parity, altitude [highlands only]). Among highland children, greater Andean ancestry was negatively associated with stature and tibia, ulna, and lower limb lengths, independent of negative associations with greater altitude for these measurements. Relationships were strongest for tibia length: each additional Andean surname or 1,000 m increase at altitude among highland children was associated with 0.18 and 0.65 z score decreases in tibia length, respectively. Anthropometry was not significantly associated with ancestry among lowland children. Greater Andean ancestry is associated with shorter stature and limb measurements at high but not low altitude. Gene-environment interactions between high altitude and Andean ancestry may exacerbate the trade-off between chest dimensions and stature that was proposed previously, though we could not test this directly. © 2015 Wiley Periodicals, Inc.

  7. Hemoglobin and hematocrit values of Saudi newborns in the high altitude of Abha, Saudi Arabia

    International Nuclear Information System (INIS)

    Bassuni, W.; Asindi, A.A.; Mustafa, F.S.; Hassan, B.; Din, Z.S.; Kumar, R.K.

    1996-01-01

    A study was designed to determine the red cell values (hemoglobin and hematocrit) of neonates born in the high altitude of Abha and to compare these values with known values of other lowland areas of Saudi Arabia. From the cord blood of 587 normal, appropriate for gestational age and term infants born in 1993 in Abha Maternity Hospital, the ranges of Hb and Hct were 130 to 240 g/L and 0.24 to 0.79 L/L respectively. The mean Hb was 187 g/L. There was no significant difference between the male and female values. Also, 17% of the infants in this study were polycythemic, while no polycythemia was recorded in these lowland areas and only 2% to 4% in the general global newborn population. It was therefore revealed that Abha newborns had higher red cell values at the birth when compared to other newborns in the low altitude areas of Riyadh and Jeddah (P<0.001). We postulate that high altitude (2700 meters above sea level) of Abha, and therefore its relative hypoxia, has induced high red cell values in infants born in the city. The phenomenon therefore warrants the adoption of higher red cell reference values and not necessarily those already documented in other Saudi new born populations. (author)

  8. Infrared color gradient in the inner coma of Comet Halley

    International Nuclear Information System (INIS)

    Campins, H.; Rieke, M.J.; Rieke, G.H.

    1989-01-01

    A well-defined gradient is noted in the J-H and H-K colors of near-IR images obtained for Comet Halley in November, 1985, within about 8000 km of the nucleus; the bluest colors are at the photocenter, in conjunction with surface brightness profiles that are steeper than those expected. The color gradient and the brightness profiles are both explainable by the present analysis in terms of the presence of volatile, dirty-ice grains in the inner coma. An outburst of Rayleigh-scattering dust particles (unsupported by spacecraft measurements obtained to date) may also account for the observational data. 27 references

  9. Correction for reflected sky radiance in low-altitude coastal hyperspectral images.

    Science.gov (United States)

    Kim, Minsu; Park, Joong Yong; Kopilevich, Yuri; Tuell, Grady; Philpot, William

    2013-11-10

    Low-altitude coastal hyperspectral imagery is sensitive to reflections of sky radiance at the water surface. Even in the absence of sun glint, and for a calm water surface, the wide range of viewing angles may result in pronounced, low-frequency variations of the reflected sky radiance across the scan line depending on the solar position. The variation in reflected sky radiance can be obscured by strong high-spatial-frequency sun glint and at high altitude by path radiance. However, at low altitudes, the low-spatial-frequency sky radiance effect is frequently significant and is not removed effectively by the typical corrections for sun glint. The reflected sky radiance from the water surface observed by a low-altitude sensor can be modeled in the first approximation as the sum of multiple-scattered Rayleigh path radiance and the single-scattered direct-solar-beam radiance by the aerosol in the lower atmosphere. The path radiance from zenith to the half field of view (FOV) of a typical airborne spectroradiometer has relatively minimal variation and its reflected radiance to detector array results in a flat base. Therefore the along-track variation is mostly contributed by the forward single-scattered solar-beam radiance. The scattered solar-beam radiances arrive at the water surface with different incident angles. Thus the reflected radiance received at the detector array corresponds to a certain scattering angle, and its variation is most effectively parameterized using the downward scattering angle (DSA) of the solar beam. Computation of the DSA must account for the roll, pitch, and heading of the platform and the viewing geometry of the sensor along with the solar ephemeris. Once the DSA image is calculated, the near-infrared (NIR) radiance from selected water scan lines are compared, and a relationship between DSA and NIR radiance is derived. We then apply the relationship to the entire DSA image to create an NIR reference image. Using the NIR reference image

  10. Snow chemistry of high altitude glaciers in the French Alps

    OpenAIRE

    MAUPETIT, FRANÇOIS; DELMAS, ROBERT J.

    2011-01-01

    Snow samples were collected as snowcores in the accumulation zone of four high altitude glaciers (2980–3540 m.a.s.l.) from each of the 4 highest mountain areas of the French Alps, during 3 consecutive years: 1989, 1990 and 1991. Sampling was performed in spring (∼ May), before the onset of late spring–summer percolation. The accumulated snow therefore reflects winter and spring conditions. A complementary sampling of fresh-snow was performed on an event basis, on one of the studied glaciers, ...

  11. Lower obesity rate during residence at high altitude among a military population with frequent migration: a quasi experimental model for investigating spatial causation.

    Directory of Open Access Journals (Sweden)

    Jameson D Voss

    Full Text Available We sought to evaluate whether residence at high altitude is associated with the development of obesity among those at increased risk of becoming obese. Obesity, a leading global health priority, is often refractory to care. A potentially novel intervention is hypoxia, which has demonstrated positive long-term metabolic effects in rats. Whether or not high altitude residence confers benefit in humans, however, remains unknown. Using a quasi-experimental, retrospective study design, we observed all outpatient medical encounters for overweight active component enlisted service members in the U.S. Army or Air Force from January 2006 to December 2012 who were stationed in the United States. We compared high altitude (>1.96 kilometers above sea level duty assignment with low altitude (<0.98 kilometers. The outcome of interest was obesity related ICD-9 codes (278.00-01, V85.3x-V85.54 by Cox regression. We found service members had a lower hazard ratio (HR of incident obesity diagnosis if stationed at high altitude as compared to low altitude (HR 0.59, 95% confidence interval [CI] 0.54-0.65; p<0.001. Using geographic distribution of obesity prevalence among civilians throughout the U.S. as a covariate (as measured by the Centers for Disease Control and Prevention and the REGARDS study also predicted obesity onset among service members. In conclusion, high altitude residence predicts lower rates of new obesity diagnoses among overweight service members in the U.S. Army and Air Force. Future studies should assign exposure using randomization, clarify the mechanism(s of this relationship, and assess the net balance of harms and benefits of high altitude on obesity prevention.

  12. Characteristics of high altitude oxygen ion energization and outflow as observed by Cluster: a statistical study

    Energy Technology Data Exchange (ETDEWEB)

    Nilsson, H.; Waara, M.; Arvelius, S.; Yamauchi, M.; Lundin, R. [Inst. of Space Physics, Kiruna (Sweden); Marghitu, O. [Max-Planck-Inst. fuer Extraterrestriche Physik, Garching (Germany); Inst. for Space Sciences, Bucharest (Romania); Bouhram, M. [Max-Planck-Inst. fuer Extraterrestriche Physik, Garching (Germany); CETP-CNRS, Saint-Maur (France); Hobara, Y. [Inst. of Space Physics, Kiruna (Sweden); Univ. of Sheffield, Sheffield (United Kingdom); Reme, H.; Sauvaud, J.A.; Dandouras, I. [Centre d' Etude Spatiale des Rayonnements, Toulouse (France); Balogh, A. [Imperial Coll. of Science, Technology and Medicine, London (United Kingdom); Kistler, L.M. [Univ. of New Hampshire, Durham (United States); Klecker, B. [Max-Planck-Inst. fuer Extraterrestriche Physik, Garching (Germany); Carlson, C.W. [Space Science Lab., Univ. of California, Berkeley (United States); Bavassano-Cattaneo, M.B. [Ist. di Fisica dello Spazio Interplanetario, Roma (Italy); Korth, A. [Max-Planck-Inst. fuer Sonnensystemforschung, Katlenburg-Lindau (Germany)

    2006-07-01

    The results of a statistical study of oxygen ion outflow using cluster data obtained at high altitude above the polar cap is reported. Moment data for both hydrogen ions (H{sup +}) and oxygen ions (O{sup +}) from 3 years (2001-2003) of spring orbits (January to May) have been used. The altitudes covered were mainly in the range 5-12 R{sub E} geocentric distance. It was found that O{sup +} is significantly transversely energized at high altitudes, indicated both by high perpendicular temperatures for low magnetic field values as well as by a tendency towards higher perpendicular than parallel temperature distributions for the highest observed temperatures. The O{sup +} parallel bulk velocity increases with altitude in particular for the lowest observed altitude intervals. O{sup +} parallel bulk velocities in excess of 60 km s{sup -1} were found mainly at higher altitudes corresponding to magnetic field strengths of less than 100 nT. For the highest observed parallel bulk velocities of O{sup +} the thermal velocity exceeds the bulk velocity, indicating that the beam-like character of the distribution is lost. The parallel bulk velocity of the H{sup +} and O{sup +} was found to typically be close to the same throughout the observation interval when the H{sup +} bulk velocity was calculated for all pitch-angles. When the H{sup +} bulk velocity was calculated for upward moving particles only the H{sup +} parallel bulk velocity was typically higher than that of O{sup +}. The parallel bulk velocity is close to the same for a wide range of relative abundance of the two ion species, including when the O{sup +} ions dominates. The thermal velocity of O{sup +} was always well below that of H{sup +}. Thus perpendicular energization that is more effective for O{sup +} takes place, but this is not enough to explain the close to similar parallel velocities. Further parallel acceleration must occur. The results presented constrain the models of perpendicular heating and parallel

  13. Characteristics of high altitude oxygen ion energization and outflow as observed by Cluster: a statistical study

    Directory of Open Access Journals (Sweden)

    H. Nilsson

    2006-05-01

    Full Text Available The results of a statistical study of oxygen ion outflow using Cluster data obtained at high altitude above the polar cap is reported. Moment data for both hydrogen ions (H+ and oxygen ions (O+ from 3 years (2001-2003 of spring orbits (January to May have been used. The altitudes covered were mainly in the range 5–12 RE geocentric distance. It was found that O+ is significantly transversely energized at high altitudes, indicated both by high perpendicular temperatures for low magnetic field values as well as by a tendency towards higher perpendicular than parallel temperature distributions for the highest observed temperatures. The O+ parallel bulk velocity increases with altitude in particular for the lowest observed altitude intervals. O+ parallel bulk velocities in excess of 60 km s-1 were found mainly at higher altitudes corresponding to magnetic field strengths of less than 100 nT. For the highest observed parallel bulk velocities of O+ the thermal velocity exceeds the bulk velocity, indicating that the beam-like character of the distribution is lost. The parallel bulk velocity of the H+ and O+ was found to typically be close to the same throughout the observation interval when the H+ bulk velocity was calculated for all pitch-angles. When the H+ bulk velocity was calculated for upward moving particles only the H+ parallel bulk velocity was typically higher than that of O+. The parallel bulk velocity is close to the same for a wide range of relative abundance of the two ion species, including when the O+ ions dominates. The thermal velocity of O+ was always well below that of H+. Thus perpendicular energization that is more effective for O+ takes place, but this is not enough to explain the close to similar parallel velocities. Further parallel acceleration must occur. The results presented constrain the models of perpendicular heating and parallel acceleration. In particular centrifugal acceleration of the outflowing ions, which may

  14. Incidence and care of environmental dermatoses in the high-altitude region of Ladakh, India

    Directory of Open Access Journals (Sweden)

    G K Singh

    2013-01-01

    Full Text Available Background : Low humidity, high-velocity wind, excessive ultraviolet (UV exposure, and extreme cold temperature are the main causes of various types of environmental dermatoses in high altitudes. Materials and Methods: A retrospective study was carried out in patients visiting the lone dermatology department in Ladakh between July 2009 and June 2010. The aim was to identify the common environmental dermatoses in high altitudes so that they can be treated easily or prevented. The patients were divided into three demographic groups, namely, lowlanders, Ladakhis (native highlanders, and tourists. Data was analyzed in a tabulated fashion. Results: A total of 1,567 patients with skin ailments were seen, of whom 965 were lowlanders, 512 native Ladakhis, and 90 were tourists. The skin disorders due to UV rays, dry skin, and papular urticaria were common among all groups. The frequency of melasma ( n = 42; 49.4%, chronic actinic dermatitis (CAD ( n = 18; 81.81% of total CAD cases, and actinic cheilitis ( n = 3; 100% was much higher among the native Ladakhis. The frequency of cold-related injuries was much lesser among Ladakhis ( n = 1; 1.19% than lowlanders ( n = 70; 83.33% and tourists ( n = 13; 15.47% ( P < 0.05. Conclusion: Dryness of skin, tanning, acute or chronic sunburn, polymorphic light reaction, CAD, insect bite reactions, chilblain, and frostbite are common environmental dermatoses of high altitudes. Avoidance of frequent application of soap, application of adequate and suitable emollient, use of effective sunscreen, and wearing of protective clothing are important guidelines for skin care in this region.

  15. Galileo infrared imaging spectroscopy measurements at venus

    Science.gov (United States)

    Carlson, R.W.; Baines, K.H.; Encrenaz, Th.; Taylor, F.W.; Drossart, P.; Kamp, L.W.; Pollack, James B.; Lellouch, E.; Collard, A.D.; Calcutt, S.B.; Grinspoon, D.; Weissman, P.R.; Smythe, W.D.; Ocampo, A.C.; Danielson, G.E.; Fanale, F.P.; Johnson, T.V.; Kieffer, H.H.; Matson, D.L.; McCord, T.B.; Soderblom, L.A.

    1991-01-01

    During the 1990 Galileo Venus flyby, the Near Infrared Mapping Spectrometer investigated the night-side atmosphere of Venus in the spectral range 0.7 to 5.2 micrometers. Multispectral images at high spatial resolution indicate substantial cloud opacity variations in the lower cloud levels, centered at 50 kilometers altitude. Zonal and meridional winds were derived for this level and are consistent with motion of the upper branch of a Hadley cell. Northern and southern hemisphere clouds appear to be markedly different. Spectral profiles were used to derive lower atmosphere abundances of water vapor and other species.

  16. Protective effects of Astragalus-Lilygranules on intestinal mucosal barrier of mice in high altitude hypoxia

    Directory of Open Access Journals (Sweden)

    Ling LI

    2016-10-01

    Full Text Available Objective  To investigate the protective effect of Astragalus-Lily Granules on intestinal mucosa and intestinal flora homeostasis in mice under high altitude hypoxia condition. Methods  We put mice into high altitude hypoxia cabin to establish high altitude hypoxia model mice. Sixty Kunming mice were randomly divided into control group, model group, Astragalus-Lily particles (ALP low, medium and high dose groups [1.75, 3.5, 7g/(kg•d] respectively. After three days of routine feeding, the ALP mice received drug by intragastric administration, once a day for continuous 17 days,control group and model group were given double distilled water in same volume. From the 15th day, all the mice but control group were exposed to simulated high altitude hypoxia condition for 3 days in a high altitude hypoxia cabin after they were gavaged for half an hour daily. By the 18th day, the fresh mouse feces were collected and smeared to observe the changes of microflora. The pathological changes of intestinal tissues were observed by HE staining and the expression of HIF-1αprotein in intestines was detected by immunohistochemistry. Results  The enterococci and gram negative bacteria showed a higher proportion (65.2%±2.4% and 56.7%±3.3%, respectively in the model group compared with the control group (24.7%±1.2%, 23.2%±1.5%, respectively, P<0.05. The pathological score of intestinal mucosal necrosis and edema (3.10±0.99, 3.30±0.67 respectively and inflammatory cell count (15.93±3.30, 16.40±3.97/ HP respectively was higher compared with the model group (0.70±0.67, 0.80±0.78; 4.07±2.12, 4.28±2.16/HP respectively; P<0.05. HIF-1αexpression increased significantly compared with the model group (P<0.05. The enterococci (46.7%±2.0%, 32.0%±2.6% respectively and gram negative bacteria rate (34.2%±1.6%, 38.0%±2.8% respectively in the ALP medium and high dose groups were lower compared with the model group (24.7%±1.2%, 23.2%±1.5% respectively, P<0

  17. High-altitude and high-latitude O+ and H+ outflows: the effect of finite electromagnetic turbulence wavelength

    Directory of Open Access Journals (Sweden)

    I. A. Barghouthi

    2007-11-01

    , consistent with the observations of H+ and O+ ions in the auroral region at high altitudes.

  18. Adaptive remodeling of skeletal muscle energy metabolism in high-altitude hypoxia: Lessons from AltitudeOmics.

    Science.gov (United States)

    Chicco, Adam J; Le, Catherine H; Gnaiger, Erich; Dreyer, Hans C; Muyskens, Jonathan B; D'Alessandro, Angelo; Nemkov, Travis; Hocker, Austin D; Prenni, Jessica E; Wolfe, Lisa M; Sindt, Nathan M; Lovering, Andrew T; Subudhi, Andrew W; Roach, Robert C

    2018-05-04

    Metabolic responses to hypoxia play important roles in cell survival strategies and disease pathogenesis in humans. However, the homeostatic adjustments that balance changes in energy supply and demand to maintain organismal function under chronic low oxygen conditions remain incompletely understood, making it difficult to distinguish adaptive from maladaptive responses in hypoxia-related pathologies. We integrated metabolomic and proteomic profiling with mitochondrial respirometry and blood gas analyses to comprehensively define the physiological responses of skeletal muscle energy metabolism to 16 days of high-altitude hypoxia (5260 m) in healthy volunteers from the AltitudeOmics project. In contrast to the view that hypoxia down-regulates aerobic metabolism, results show that mitochondria play a central role in muscle hypoxia adaptation by supporting higher resting phosphorylation potential and enhancing the efficiency of long-chain acylcarnitine oxidation. This directs increases in muscle glucose toward pentose phosphate and one-carbon metabolism pathways that support cytosolic redox balance and help mitigate the effects of increased protein and purine nucleotide catabolism in hypoxia. Muscle accumulation of free amino acids favor these adjustments by coordinating cytosolic and mitochondrial pathways to rid the cell of excess nitrogen, but might ultimately limit muscle oxidative capacity in vivo Collectively, these studies illustrate how an integration of aerobic and anaerobic metabolism is required for physiological hypoxia adaptation in skeletal muscle, and highlight protein catabolism and allosteric regulation as unexpected orchestrators of metabolic remodeling in this context. These findings have important implications for the management of hypoxia-related diseases and other conditions associated with chronic catabolic stress. © 2018 by The American Society for Biochemistry and Molecular Biology, Inc.

  19. Serum creatine kinase elevations in ultramarathon runners at high altitude.

    Science.gov (United States)

    Magrini, Danielle; Khodaee, Morteza; San-Millán, Iñigo; Hew-Butler, Tamara; Provance, Aaron J

    2017-05-01

    Creatine kinase (CK) is a sensitive enzyme marker for muscle damage in athletes. Elevated CK levels have been reported in many endurance physical activities. The consequence and possible long-term sequela of the CK elevation in athletes is unknown. There is a paucity of literature stating actual numerical values of CK associated with competing in an ultramarathon with extreme environmental conditions. Our hypothesis was that the serum CK levels increase significantly as a result of running a 161 km ultramarathon at high altitude. This was a prospective observational study of participants of the Leadville 100 ultramarathon race in Leadville, Colorado at high altitude (2800-3840 m) in August 2014. We collected blood samples from sixty-four volunteer runners before and eighty-three runners immediately after the race. Out of 669 athletes who started the race, 352 successfully completed the race in less than the 30-hour cut-off time (52%). The majority of runners were male (84%). We were able to collect both pre- and post-race blood samples from 36 runners. Out of these 36 runners, the mean pre-race CK was increased from 126 ± 64 U/L to 14,569 ± 14,729 U/L (p athletes' age, BMI, or finishing time. Significant elevation of CK level occurs as a result of running ultramarathons. The majority of athletes with significantly elevated CK levels were asymptomatic and required no major medical attention.

  20. Beta-fibrinogen allele frequencies in Peruvian Quechua, a high-altitude native population.

    Science.gov (United States)

    Rupert, J L; Devine, D V; Monsalve, M V; Hochachka, P W

    1999-06-01

    Elevated hematocrits, which are found in many high-altitude populations, increase the oxygen-carrying capacity of blood and may represent an adaptation to hypoxic environments. However, as high hematocrit increases blood viscosity, which in turn is associated with hypertension and heart disease, it may be advantageous for high-altitude populations to limit other factors that contribute to increased blood viscosity. One such factor is the plasma concentration of the coagulation protein fibrinogen. Several common polymorphisms in the beta-fibrinogen gene have been identified that affect fibrinogen concentrations. We determined the allele frequencies of three of these polymorphisms (G/A-455(HaeIII), C/T-148(HindIII), and G/A+448(MnlI)) in sample groups drawn from three populations: Quechua-speaking natives living at over 3,200 m in the Peruvian Andes, North American natives (Na-Dene) from coastal British Columbia, and Caucasian North Americans. The frequencies of the alleles previously shown to be associated with increased fibrinogen levels were so low in the Quechuas that their presence could be accounted for solely by genetic admixture with Caucasians. Frequencies in the Na-Dene, a Native American group unrelated to the Quechua, were not significantly different from those in Caucasians.

  1. Mössbauer studies of hemoglobin in high altitude polycythemia

    Science.gov (United States)

    Xiufang, Zhang; Linming, Shen; Songsen, Chen; Yuanyuan, Liu; Naifei, Gao; Yuanming, Zheng; Zhaohui, Ao; Liangquan, Shong

    1990-07-01

    The Mössbauer spectra have been measured in erythrocytes from normal adults and the patients with high altitude polycythemia (HAPC). The results indicated that two subspectra “a” and “b”, corresponding to oxy- and deoxyhemoglobin respectively, were present in all blood samples, and a third subspectrum “c” was found to exist in almost all samples from the patients. The parameters of the third subspectra “cl” in most samples from the patients were similar to those of carbon monoxyhemoglobin. The components were considered to be the denatured hemoglobin in RBCs (red blood cells). Together with clinical analysis, a possible mechanism of HAPC has been discussed.

  2. Adjustment of measurement errors to reconcile precipitation distribution in the high-altitude Indus basin

    NARCIS (Netherlands)

    Dahri, Zakir Hussain; Moors, Eddy; Ludwig, Fulco; Ahmad, Shakil; Khan, Asif; Ali, Irfan; Kabat, Pavel

    2018-01-01

    Precipitation in the high-altitude Indus basin governs its renewable water resources affecting water, energy and food securities. However, reliable estimates of precipitation climatology and associated hydrological implications are seriously constrained by the quality of observed data. As such,

  3. WCDMA Uplink Interference Assessment from Multiple High Altitude Platform Configurations

    Directory of Open Access Journals (Sweden)

    Grace D

    2008-01-01

    Full Text Available Abstract We investigate the possibility of multiple high altitude platform (HAP coverage of a common cell area using a wideband code division multiple access (WCDMA system. In particular, we study the uplink system performance of the system. The results show that depending on the traffic demand and the type of service used, there is a possibility of deploying 3–6 HAPs covering the same cell area. The results also show the effect of cell radius on performance and the position of the multiple HAP base stations which give the worst performance.

  4. Infrared absorption spectroscopy and chemical kinetics of free radicals

    Energy Technology Data Exchange (ETDEWEB)

    Curl, R.F.; Glass, G.P. [Rice Univ., Houston, TX (United States)

    1993-12-01

    This research is directed at the detection, monitoring, and study of chemical kinetic behavior by infrared absorption spectroscopy of small free radical species thought to be important intermediates in combustion. During the last year, infrared kinetic spectroscopy using excimer laser flash photolysis and color-center laser probing has been employed to study the high resolution spectrum of HCCN, the rate constant of the reaction between ethynyl (C{sub 2}H) radical and H{sub 2} in the temperature region between 295 and 875 K, and the recombination rate of propargyl (CH{sub 2}CCH) at room temperature.

  5. A Strong High Altitude Narrow Jet At Saturn'S Equator From Cassini/ISS Images

    Science.gov (United States)

    Garcia-Melendo, Enrique; Sánchez-Lavega, A.; Legarreta, J.; Pérez-Hoyos, S.; Hueso, R.

    2010-10-01

    The intense equatorial eastward jets observed at cloud level in Jupiter and Saturn, represent a major challenge for geophysical fluid dynamics. Saturn's equatorial jet is of particular interest in view of its three dimensional structure, suspected large temporal variability, and related stratospheric semiannual oscillation. Here we report the discovery at the upper cloud level of an extremely narrow and strong jet centered in the middle of the broad equatorial jet. Previously published works on Saturn's equatorial winds at cloud level provided only a partial coverage. Automatic correlation of brightness scans and manually tracked cloud features, retrieved from images obtained by the Cassini Imaging Science Subsystem (ISS), show that the jet reaches 430 ms-1 with a peak speed difference of 180 ms-1 relative to nearby latitudes at 60 mbar and 390 ms-1 at depths > 500 mbar. Images were obtained in two filters: MT3, centred at the 889nm strong methane absorption band, and CB3 centred at the near infrared 939nm continuum, which are sensitive to different altitude levels at the upper clouds and hazes. Contrarily to what is observed in other latitudes, its velocity increases with altitude. Our findings helps to extend the view we have of the equatorial stratospheric dynamics of fast rotating planets beyond the best known terrestrial environment, and extract more general consequences of the interaction between waves and mean flow. It remains to be known if this equatorial jet structure, now determined in detail in three dimensions, is permanent or variable with the seasonal solar insolation cycle, including the variable shadow cast by the rings. EGM, ASL, JL, SPH, and RH have been funded by the Spanish MICIIN AYA2009-10701 with FEDER support and ASL, JL, SPH, and RH by Grupos Gobierno Vasco IT-464-07

  6. Research on infrared radiation characteristics of Pyromark1200 high-temperature coating

    Science.gov (United States)

    Song, Xuyao; Huan, Kewei; Dong, Wei; Wang, Jinghui; Zang, Yanzhe; Shi, Xiaoguang

    2014-11-01

    Pyromark 1200 (Tempil Co, USA), which is a type of high-temperature high-emissivity coating, is silicon-based with good thermal radiation performance. Its stably working condition is at the temperature range 589~922 K thus a wide range of applications in industrial, scientific research, aviation, aerospace and other fields. Infrared emissivity is one of the most important factors in infrared radiation characteristics. Data on infrared spectral emissivity of Pyromark 1200 is in shortage, as well as the reports on its infrared radiation characteristics affected by its spray painting process, microstructure and thermal process. The results of this research show that: (1) The coating film critical thickness on the metal base is 10μm according to comparison among different types of spray painting process, coating film thickness, microstructure, which would influence the infrared radiation characteristics of Pyromark 1200 coating. The infrared spectral emissivity will attenuate when the coating film thickness is lower or much higher than that. (2) Through measurements, the normal infrared radiation characteristics is analyzed within the range at the temperature range 573~873 K under normal atmospheric conditions, and the total infrared spectral emissivity of Pyromark 1200 coating is higher than 0.93 in the 3~14 μm wavelength range. (3) The result of 72-hour aging test at the temperature 673 K which studied the effect of thermal processes on the infrared radiation characteristics of the coating shows that the infrared spectral emissivity variation range is approximately 0.01 indicating that Pyromark 1200 coating is with good stability. Compared with Nextel Velvet Coating (N-V-C) which is widely used in optics field, Pyromark 1200 high-temperature coating has a higher applicable temperature and is more suitable for spraying on the material surface which is in long-term operation under high temperature work conditions and requires high infrared spectral emissivity.

  7. Oxidative stress at high altitude: genotype–phenotype correlations

    Directory of Open Access Journals (Sweden)

    Pandey P

    2014-05-01

    Full Text Available Priyanka Pandey,1,2 MA Qadar Pasha1,2 1CSIR-Institute of Genomics and Integrative Biology, Delhi, India; 2Department of Biotechnology, University of Pune, Ganeshkhind, Pune, India Abstract: It has been well-documented that the hypobaric hypoxic environment at high altitude (HA causes stress to both the permanent residents of HA and the sojourners. This oxidative stress primarily disturbs the oxygen-sensing and vascular homeostasis pathways, thereby upsetting normal human physiology, especially in sojourners. These environmental challenges have caused dynamic evolutionary changes within natives of HA, allowing them to develop adaptive plasticity. This review focuses on the genomic and biochemical features of the molecules involved in the oxygen-sensing and vascular homeostasis pathways with respect to HA pulmonary edema (HAPE and adaptation. We review the role of genetic markers such as HIF-prolyl hydroxylase 2, endothelial PAS domain-containing protein 1, endothelial nitric oxide synthase, endothelin 1, cytochrome b-245 alpha polypeptide, and glutathione S-transferase pi 1, as well as three circulatory biomarkers (nitric oxide, endothelin 1, and 8-iso-prostaglandin F2α, by highlighting approaches such as candidate gene and genome-wide, adopted in deciphering the pathways. A disagreement between the two approaches has also been highlighted. In addition, we discuss that an overrepresentation of wild-type alleles in HA natives and mutant alleles of same polymorphisms in HAPE patients implies that the allelic variants at the same locus are involved in adaptation and HAPE, respectively. Moreover, healthy sojourners present a number of genomic features similar to HA natives, further strengthening the concept of genetic predisposition. A trend in correlation between protective and risk alleles and altered levels of circulatory markers clearly documents the phenomenon of genotype–phenotype correlations. We conclude that the genetic and biochemical

  8. Serum irisin and myostatin levels after 2 weeks of high-altitude climbing.

    Directory of Open Access Journals (Sweden)

    Ewa Śliwicka

    Full Text Available Exposure to high-altitude hypoxia causes physiological and metabolic adaptive changes by disturbing homeostasis. Hypoxia-related changes in skeletal muscle affect the closely interconnected energy and regeneration processes. The balance between protein synthesis and degradation in the skeletal muscle is regulated by several molecules such as myostatin, cytokines, vitamin D, and irisin. This study investigates changes in irisin and myostatin levels in male climbers after a 2-week high-altitude expedition, and their association with 25(OHD and indices of inflammatory processes. The study was performed in 8 men aged between 23 and 31 years, who participated in a 2-week climbing expedition in the Alps. The measurements of body composition and serum concentrations of irisin, myostatin, 25(OHD, interleukin-6, myoglobin, high-sensitivity C-reactive protein, osteoprotegerin, and high-sensitivity soluble receptor activator of NF-κB ligand (sRANKL were performed before and after expedition. A 2-week exposure to hypobaric hypoxia caused significant decrease in body mass, body mass index (BMI, free fat mass and irisin, 25-Hydroxyvitamin D levels. On the other hand, significant increase in the levels of myoglobin, high-sensitivity C-reactive protein, interleukin-6, and osteoprotegerin were noted. The observed correlations of irisin with 25(OHD levels, as well as myostatin levels with inflammatory markers and the OPG/RANKL ratio indicate that these myokines may be involved in the energy-related processes and skeletal muscle regeneration in response to 2-week exposure to hypobaric hypoxia.

  9. Serum irisin and myostatin levels after 2 weeks of high-altitude climbing.

    Science.gov (United States)

    Śliwicka, Ewa; Cisoń, Tomasz; Kasprzak, Zbigniew; Nowak, Alicja; Pilaczyńska-Szcześniak, Łucja

    2017-01-01

    Exposure to high-altitude hypoxia causes physiological and metabolic adaptive changes by disturbing homeostasis. Hypoxia-related changes in skeletal muscle affect the closely interconnected energy and regeneration processes. The balance between protein synthesis and degradation in the skeletal muscle is regulated by several molecules such as myostatin, cytokines, vitamin D, and irisin. This study investigates changes in irisin and myostatin levels in male climbers after a 2-week high-altitude expedition, and their association with 25(OH)D and indices of inflammatory processes. The study was performed in 8 men aged between 23 and 31 years, who participated in a 2-week climbing expedition in the Alps. The measurements of body composition and serum concentrations of irisin, myostatin, 25(OH)D, interleukin-6, myoglobin, high-sensitivity C-reactive protein, osteoprotegerin, and high-sensitivity soluble receptor activator of NF-κB ligand (sRANKL) were performed before and after expedition. A 2-week exposure to hypobaric hypoxia caused significant decrease in body mass, body mass index (BMI), free fat mass and irisin, 25-Hydroxyvitamin D levels. On the other hand, significant increase in the levels of myoglobin, high-sensitivity C-reactive protein, interleukin-6, and osteoprotegerin were noted. The observed correlations of irisin with 25(OH)D levels, as well as myostatin levels with inflammatory markers and the OPG/RANKL ratio indicate that these myokines may be involved in the energy-related processes and skeletal muscle regeneration in response to 2-week exposure to hypobaric hypoxia.

  10. Airborne Mission Concept for Coastal Ocean Color and Ecosystems Research

    Science.gov (United States)

    Guild, Liane S.; Hooker, Stanford B.; Morrow, John H.; Kudela, Raphael M.; Palacios, Sherry L.; Torres Perez, Juan L.; Hayashi, Kendra; Dunagan, Stephen E.

    2016-01-01

    NASA airborne missions in 2011 and 2013 over Monterey Bay, CA, demonstrated novel above- and in-water calibration and validation measurements supporting a combined airborne sensor approach (imaging spectrometer, microradiometers, and a sun photometer). The resultant airborne data characterize contemporaneous coastal atmospheric and aquatic properties plus sea-truth observations from state-of-the-art instrument systems spanning a next-generation spectral domain (320-875 nm). This airborne instrument suite for calibration, validation, and research flew at the lowest safe altitude (ca. 100 ft or 30 m) as well as higher altitudes (e.g., 6,000 ft or 1,800 m) above the sea surface covering a larger area in a single synoptic sortie than ship-based measurements at a few stations during the same sampling period. Data collection of coincident atmospheric and aquatic properties near the sea surface and at altitude allows the input of relevant variables into atmospheric correction schemes to improve the output of corrected imaging spectrometer data. Specific channels support legacy and next-generation satellite capabilities, and flights are planned to within 30 min of satellite overpass. This concept supports calibration and validation activities of ocean color phenomena (e.g., river plumes, algal blooms) and studies of water quality and coastal ecosystems. The 2011 COAST mission flew at 100 and 6,000 ft on a Twin Otter platform with flight plans accommodating the competing requirements of the sensor suite, which included the Coastal-Airborne In-situ Radiometers (C-AIR) for the first time. C-AIR (Biospherical Instruments Inc.) also flew in the 2013 OCEANIA mission at 100 and 1,000 ft on the Twin Otter below the California airborne simulation of the proposed NASA HyspIRI satellite system comprised of an imaging spectrometer and thermal infrared multispectral imager on the ER-2 at 65,000 ft (20,000 m). For both missions, the Compact-Optical Profiling System (Biospherical

  11. Plasmonic color metasurfaces fabricated by a high speed roll-to-roll method

    DEFF Research Database (Denmark)

    Murthy, Swathi; Pranov, Henrik; Feidenhans'l, Nikolaj Agentoft

    2017-01-01

    Lab-scale plasmonic color printing using nano-structured and subsequently metallized surfaces have been demonstrated to provide vivid colors. However, upscaling these structures for large area manufacturing is extremely challenging due to the requirement of nanometer precision of metal thickness....... In this study, we have investigated a plasmonic color meta-surface design that can be easily upscaled. We have demonstrated the feasibility of fabrication of these plasmonic color surfaces by a high-speed roll-to-roll method, comprising roll-to-roll extrusion coating at 10 m min-1 creating a polymer foil having...... 100 nm deep pits of varying sub-wavelength diameter and pitch length. Subsequently this polymer foil was metallized and coated also by high-speed roll-to-roll methods. The perceived colors have high tolerance towards the thickness of the metal layer, when this thickness exceeds the depths of the pits...

  12. Bimodal star formation - constraints from galaxy colors at high redshift

    International Nuclear Information System (INIS)

    Wyse, R.F.G.; Silk, J.

    1987-01-01

    The possibility that at early epochs the light from elliptical galaxies is dominated by stars with an initial mass function (IMF) which is deficient in low-mass stars, relative to the solar neighborhood is investigated. V-R colors for the optical counterparts of 3CR radio sources offer the most severe constraints on the models. Reasonable fits are obtained to both the blue, high-redshift colors and the redder, low-redshift colors with a model galaxy which forms with initially equal star formation rates in each of two IMF modes: one lacking low-mass stars, and one with stars of all masses. The net effect is that the time-integrated IMF has twice as many high-mass stars as the solar neighborhood IMF, relative to low mass stars. A conventional solar neighborhood IMF does not simultaneously account for both the range in colors at high redshift and the redness of nearby ellipticals, with any single star formation epoch. Models with a standard IMF require half the stellar population to be formed in a burst at low redshift z of about 1. 38 references

  13. Highway pavement performance test for colored thin anti-skidding layers

    Science.gov (United States)

    Gao, Wei; Cui, Wei; Xu, Ming

    2018-03-01

    Based on the actual service condition of highway pavement colored thin anti-skidding layers, with materials of color quartz sand and two-component acrylic resin as basis, we designed such tests as the bond strength, shearing strength, tear strength, fatigue performance and aggregate polished value, and included the freeze-thaw cycle and de-icing salt and other factors in the experiment, connecting with the climate characteristics of circumpolar latitude and low altitude in Heilongjiang province. Through the pavement performance test, it is confirmed that the colored thin anti-skidding layers can adapt to cold and humid climate conditions, and its physical mechanical properties are good.

  14. High-Altitude Platforms - Present Situation and Technology Trends

    Directory of Open Access Journals (Sweden)

    Flavio Araripe D'Oliveira

    2016-07-01

    Full Text Available High-altitude platforms (HAPs are aircraft, usually unmanned airships or airplanes positioned above 20 km, in the stratosphere, in order to compose a telecommunications network or perform remote sensing. In the 1990 and 2000 decades, several projects were launched, but very few had continued. In 2014, 2 major Internet companies (Google and Facebook announced investments in new HAP projects to provide Internet access in regions without communication infrastructure (terrestrial or satellite, bringing back attention to the development of HAP. This article aims to survey the history of HAPs, the current state-of-the-art (April 2016, technology trends and challenges. The main focus of this review will be on technologies directly related to the aerial platform, inserted in the aeronautical engineering field of knowledge, not detailing aspects of the telecommunications area.

  15. Serum immunoreactive erythropoietin in high altitude natives with and without excessive erythrocytosis.

    Science.gov (United States)

    León-Velarde, F; Monge, C C; Vidal, A; Carcagno, M; Criscuolo, M; Bozzini, C E

    1991-05-01

    We report the estimation of blood hemoglobin (Hb), arterial blood oxygen saturation (SaO2), and serum immunoreactive erythropoietin (siEPO) in a group of Peruvian workers residing in Cerro de Pasco at 4300 m showing "excessive erythrocytosis" (EE, Monge's disease, chronic mountain sickness). These estimates were compared with those of humans residing either in Cerro de Pasco and showing "normal erythrocytosis" (NE) or in Lima (sea level, SL) to determine whether Hb and SaO2 are related to siEPO in high altitude (HA) natives with NE or EE. The three parameters showed statistically significant differences between HA and SL groups--the values in SL being lower. Significant differences were also found between NE and EE groups in Hb and SaO2. There was no statistical difference in siEPo between the two groups. The results indicate, therefore, that HA residents who develop EE are not distinguishable from residents who develop NE on the basis of estimates of siEPO. As a result, siEPO and Hb do not show a dose-response relationship in HA residents, and variation in EPO does not explain the striking variation in Hb at high altitudes.

  16. Haematology and erythrocyte metabolism in man at high altitude: an Aymara-Quechua comparison.

    Science.gov (United States)

    Arnaud, J; Gutierrez, N; Tellez, W; Vergnes, H

    1985-07-01

    In the course of haematological and biological investigations among Aymara and Quechua populations in Bolivia, an anthropological study of the erythrocytary respiratory function was carried out on the two groups at two altitudes: 3,600 m and 450 m. A difference in the intensity of the biological variations of the two populations is observed at high altitude. In the Quechuas, as in any lowland native, the adaptative phenomena are totally and quickly reversible. In the Aymaras, we detected the existence of more marked haematological and biochemical characters: moderate polycythemia, hyperhaemoglobinemia, microcytosis, metabolical hyperactivity with accumulation of 2-3 di-phosphoglycerate and ATP, and methaemoglobinemia with a drop in the activity of the methaemoglobin reductases. The Aymaras preserve some of those characters (methaemoglobinemia excepted) when they settle in lowlands.

  17. ABOUT TRANSITION ALTITUDE IN RUSSIAN FEDERATION

    Directory of Open Access Journals (Sweden)

    2016-01-01

    Full Text Available This article is about establishing a common transition altitude over all territory of Russian Federation. The main objective is to prove the necessity of a common transition altitude in Russian airspace and to define, which variant of tran- sition altitude (low, medium, high is the most suitable to be implemented in Russia. ICAO and IFALPA points of view, data and experience from different states and regions all over the world were examined in order to show all the advantages and disadvantages of different approaches towards common transition altitude. The research showed that the most appro- priate common transition altitude in Russia will be 10000 feet (3050 meters, it will cover almost all the international aero- dromes and regions in the country. Only several exceptions are needed in mountainous areas. This article can be used to further study of the possibility of implementation of common transition altitude, because it can’t take into consideration all the local features of all the FIRs (Flight Information Regions in Russia. The conclusion is establishing a common transi- tion altitude over such a big part of the world as Russian Federation will lead to improvement of the flight safety, harmoni- zation with ICAO and IFALPA policies and flexibility in airspace design.

  18. HIGH RESOLUTION NEAR-INFRARED SURVEY OF THE PIPE NEBULA. I. A DEEP INFRARED EXTINCTION MAP OF BARNARD 59

    International Nuclear Information System (INIS)

    Roman-Zuniga, Carlos G.; Alves, Joao F.; Lada, Charles J.

    2009-01-01

    We present our analysis of a fully sampled, high resolution dust extinction map of the Barnard 59 complex in the Pipe Nebula. The map was constructed with the infrared color excess technique applied to a photometric catalog that combines data from both ground and space based observations. The map resolves for the first time the high density center of the main core in the complex, which is associated with the formation of a small cluster of stars. We found that the central core in Barnard 59 shows an unexpected lack of significant substructure consisting of only two significant fragments. Overall, the material appears to be consistent with being a single, large core with a density profile that can be well fit by a King model. A series of NH 3 pointed observations toward the high column density center of the core appear to show that the core is still thermally dominated, with subsonic non-thermal motions. The stars in the cluster could be providing feedback to support the core against collapse, but the relatively narrow radio lines suggest that an additional source of support, for example, a magnetic field, may be required to stabilize the core. Outside the central core our observations reveal the structure of peripheral cores and resolve an extended filament into a handful of significant substructures whose spacing and masses appear to be consistent with Jeans fragmentation.

  19. Trekking at high altitudes. How safe is it for your patients?

    Science.gov (United States)

    Houston, C S

    1990-07-01

    Even healthy persons may experience some form of altitude illness when they hike or ski in high mountains. Therefore, it is imperative that those with compromised cardiac or pulmonary function take extra precautions by allowing time for ascent, by recognizing and accepting their limitations, and by descending promptly at the first sign of trouble. Certain medications, such as anticoagulants and strong tranquilizers, are probably best discontinued at higher elevations. In all caes, preventive and treatment measures should be available.

  20. MAPPING NON-INDIGENOUS EELGRASS ZOSTERA JAPONICA, ASSOCIATED MACROALGAE AND EMERGENT AQUATIC VEGETARIAN HABITATS IN A PACIFIC NORTHWEST ESTUARY USING NEAR-INFRARED COLOR AERIAL PHOTOGRAPHY AND A HYBRID IMAGE CLASSIFICATION TECHNIQUE

    Science.gov (United States)

    We conducted aerial photographic surveys of Oregon's Yaquina Bay estuary during consecutive summers from 1997 through 2001. Imagery was obtained during low tide exposures of intertidal mudflats, allowing use of near-infrared color film to detect and discriminate plant communitie...

  1. The HAMMER: High altitude multiple mission environmental researcher

    Science.gov (United States)

    Hayashi, Darren; Zylla, Cara; Amaro, Ernesto; Colin, Phil; Klause, Thomas; Lopez, Bernardo; Williamson, Danna

    1991-01-01

    At the equator, the ozone layer ranges from 65,000 to 130,000+ feet which is beyond the capabilities of the ER-2, NASA's current high altitude reconnaissance aircraft. The Universities Space Research Association, in cooperation with NASA, is sponsoring an undergraduate program which is geared to designing an aircraft that can study the ozone layer at the equator. This aircraft must be able to satisfy four mission profiles. Mission one is a polar mission which ranges from Chile to the South Pole and back to Chile, a total range of 6000 n. mi. at 100,000 feet with a 2500 lb. payload. The second mission is also a polar mission with a decreased altitude of 70,000 feet and an increased payload of 4000 lb. For the third mission, the aircraft will take-off at NASA Ames, cruise at 100,000 feet carrying a 2500 lb. payload, and land in Puerto Montt, Chile. The final mission requires the aircraft to take-off at NASA Ames, cruise at 100,000 feet with a 1000 lb. payload, make an excursion to 120,000 feet, and land at Howard AFB, Panama. All three missions require that a subsonic Mach number is maintained due to constraints imposed by the air sampling equipment. The aircraft need not be manned for all four missions. Three aircraft configurations were determined to be the most suitable for meeting the above requirements. The performance of each configuration is analyzed to investigate the feasibility of the project requirements. In the event that a requirement can not be obtained within the given constraints, recommendations for proposal modifications are given.

  2. Satellite Ocean Color Sensor Design Concepts and Performance Requirements

    Science.gov (United States)

    McClain, Charles R.; Meister, Gerhard; Monosmith, Bryan

    2014-01-01

    In late 1978, the National Aeronautics and Space Administration (NASA) launched the Nimbus-7 satellite with the Coastal Zone Color Scanner (CZCS) and several other sensors, all of which provided major advances in Earth remote sensing. The inspiration for the CZCS is usually attributed to an article in Science by Clarke et al. who demonstrated that large changes in open ocean spectral reflectance are correlated to chlorophyll-a concentrations. Chlorophyll-a is the primary photosynthetic pigment in green plants (marine and terrestrial) and is used in estimating primary production, i.e., the amount of carbon fixed into organic matter during photosynthesis. Thus, accurate estimates of global and regional primary production are key to studies of the earth's carbon cycle. Because the investigators used an airborne radiometer, they were able to demonstrate the increased radiance contribution of the atmosphere with altitude that would be a major issue for spaceborne measurements. Since 1978, there has been much progress in satellite ocean color remote sensing such that the technique is well established and is used for climate change science and routine operational environmental monitoring. Also, the science objectives and accompanying methodologies have expanded and evolved through a succession of global missions, e.g., the Ocean Color and Temperature Sensor (OCTS), the Seaviewing Wide Field-of-view Sensor (SeaWiFS), the Moderate Resolution Imaging Spectroradiometer (MODIS), the Medium Resolution Imaging Spectrometer (MERIS), and the Global Imager (GLI). With each advance in science objectives, new and more stringent requirements for sensor capabilities (e.g., spectral coverage) and performance (e.g., signal-to-noise ratio, SNR) are established. The CZCS had four bands for chlorophyll and aerosol corrections. The Ocean Color Imager (OCI) recommended for the NASA Pre-Aerosol, Cloud, and Ocean Ecosystems (PACE) mission includes 5 nanometers hyperspectral coverage from 350 to

  3. Appendix C: A comparative study of small scale remotely sensed data for monitoring clearcutting in hardwood forests. M.S. Thesis; [Allegheny National Forest, Pennsylvania and the Adirondacks, New York

    Science.gov (United States)

    Hafker, W. R.

    1980-01-01

    Manual photointerpretation techniques were used to analyze images acquired by high altitude aircraft, the Skylab multispectral and Earth terrain camera (ETC), the LANDSAT multispectral scanner, and the LANDSAT-3 return beam vidicon camera. A color-additive viewer, and digital image analysis were also used on the LANDSAT MSS imagery. The value of each type of remotely sensed data was judged by the ease and accuracy of clearcut identification, and by the amount of detail discernible, especially regarding revegetation. Results of a site study in the Allegheny National Forest, Pennsylvania indicate that high altitude aerial photography, especially color infrared photography acquired during the growing season, is well suited for identifying clearcuts and assessing revegetation. Although photographs acquired with Skylab's ETC also yielded good results, only incomplete inventories of clearcuts could be made using LANDSAT imagery. Results for the Adirondack region of New York State were similar for the aircraft and satellite photography, but even less satisfactory for the LANDSAT imagery.

  4. Changes in balance and joint position sense during a 12-day high altitude trek: The British Services Dhaulagiri medical research expedition.

    Directory of Open Access Journals (Sweden)

    Sarah B Clarke

    Full Text Available Postural control and joint position sense are essential for safely undertaking leisure and professional activities, particularly at high altitude. We tested whether exposure to a 12-day trek with a gradual ascent to high altitude impairs postural control and joint position sense. This was a repeated measures observational study of 12 military service personnel (28±4 years. Postural control (sway velocity measured by a portable force platform during standing balance, a Sharpened Romberg Test and knee joint position sense were measured, in England (113m elevation and at 3 research camps (3619m, 4600m and 5140m on a 12-day high altitude trek in the Dhaulagiri region of Nepal. Pulse oximetry, and Lake Louise scores were also recorded on the morning and evening of each trek day. Data were compared between altitudes and relationships between pulse oximetry, Lake Louise score, and sway velocity were explored. Total sway velocity during standing balance with eyes open (p = 0.003, d = 1.9 and during Sharpened Romberg test with eyes open (p = 0.007, d = 1.6 was significantly greater at altitudes of 3619m and 5140m when compared with sea level. Anterior-posterior sway velocity during standing balance with eyes open was also significantly greater at altitudes of 3619m and 5140m when compared with sea level (p = 0.001, d = 1.9. Knee joint position sense was not altered at higher altitudes. There were no significant correlations between Lake Louise scores, pulse oximetry and postural sway. Despite a gradual ascent profile, exposure to 3619 m was associated with impairments in postural control without impairment in knee joint position sense. Importantly, these impairments did not worsen at higher altitudes of 4600 m or 5140 m. The present findings should be considered during future trekking expeditions when developing training strategies targeted to manage impairments in postural control that occur with increasing altitude.

  5. Changes in balance and joint position sense during a 12-day high altitude trek: The British Services Dhaulagiri medical research expedition.

    Science.gov (United States)

    Clarke, Sarah B; Deighton, Kevin; Newman, Caroline; Nicholson, Gareth; Gallagher, Liam; Boos, Christopher J; Mellor, Adrian; Woods, David R; O'Hara, John P

    2018-01-01

    Postural control and joint position sense are essential for safely undertaking leisure and professional activities, particularly at high altitude. We tested whether exposure to a 12-day trek with a gradual ascent to high altitude impairs postural control and joint position sense. This was a repeated measures observational study of 12 military service personnel (28±4 years). Postural control (sway velocity measured by a portable force platform) during standing balance, a Sharpened Romberg Test and knee joint position sense were measured, in England (113m elevation) and at 3 research camps (3619m, 4600m and 5140m) on a 12-day high altitude trek in the Dhaulagiri region of Nepal. Pulse oximetry, and Lake Louise scores were also recorded on the morning and evening of each trek day. Data were compared between altitudes and relationships between pulse oximetry, Lake Louise score, and sway velocity were explored. Total sway velocity during standing balance with eyes open (p = 0.003, d = 1.9) and during Sharpened Romberg test with eyes open (p = 0.007, d = 1.6) was significantly greater at altitudes of 3619m and 5140m when compared with sea level. Anterior-posterior sway velocity during standing balance with eyes open was also significantly greater at altitudes of 3619m and 5140m when compared with sea level (p = 0.001, d = 1.9). Knee joint position sense was not altered at higher altitudes. There were no significant correlations between Lake Louise scores, pulse oximetry and postural sway. Despite a gradual ascent profile, exposure to 3619 m was associated with impairments in postural control without impairment in knee joint position sense. Importantly, these impairments did not worsen at higher altitudes of 4600 m or 5140 m. The present findings should be considered during future trekking expeditions when developing training strategies targeted to manage impairments in postural control that occur with increasing altitude.

  6. Long-Term Intermittent Exposure to High Altitude Elevates Asymmetric Dimethylarginine in First Exposed Young Adults.

    Science.gov (United States)

    Lüneburg, Nicole; Siques, Patricia; Brito, Julio; De La Cruz, Juan José; León-Velarde, Fabiola; Hannemann, Juliane; Ibanez, Cristian; Böger, Rainer H

    2017-09-01

    Lüneburg, Nicole, Patricia Siques, Julio Brito, Juan José De La Cruz, Fabiola León-Velarde, Juliane Hannemann, Cristian Ibanez, and Rainer Böger. Long-term intermittent exposure to high altitude elevates asymmetric dimethylarginine in first exposed young adults. High Alt Med Biol. 18:226-233, 2017.-Hypoxia-induced dysregulation of pulmonary and cerebral circulation may be related to an impaired nitric oxide (NO) pathway. We investigated the effect of chronic intermittent hypobaric hypoxia (CIH) on metabolites of the NO pathway. We measured asymmetric and symmetric dimethylarginine (ADMA and SDMA) and monomethyl-L-arginine (L-NMMA) and assessed their associations with acclimatization in male draftees (n = 72) undergoing CIH shifts at altitude (3550 m) during 3 months. Sixteen Andean natives living at altitude (3675 m) (chronic hypobaric hypoxia [CH]) were included for comparison. In CIH, ADMA and L-NMMA plasma concentrations increased from 1.14 ± 0.04 to 1.95 ± 0.09 μmol/L (mean ± SE) and from 0.22 ± 0.07 to 0.39 ± 0.03 μmol/L, respectively, (p < 0.001 for both) after 3 months, whereas SDMA did not change. The concentrations of ADMA and L-NMMA were higher in CH (3.48 ± 0.07, 0.53 ± 0.08 μmol/L; p < 0.001) as compared with CIH. In both CIH and CH, ADMA correlated with hematocrit (r 2  = 0.07, p < 0.05; r 2  = 0.26; p < 0.01). In CIH, an association of ADMA levels with poor acclimatization status was observed. We conclude that the endogenous NO synthase inhibitors, ADMA and L-NMMA, are elevated in hypoxia. This may contribute to impaired NO production at altitude and may also be predictive of altitude-associated health impairment.

  7. Four Weeks of Classical Altitude Training Increases Resting Metabolic Rate in Highly Trained Middle-Distance Runners.

    Science.gov (United States)

    Woods, Amy L; Sharma, Avish P; Garvican-Lewis, Laura A; Saunders, Philo U; Rice, Anthony J; Thompson, Kevin G

    2017-02-01

    High altitude exposure can increase resting metabolic rate (RMR) and induce weight loss in obese populations, but there is a lack of research regarding RMR in athletes at moderate elevations common to endurance training camps. The present study aimed to determine whether 4 weeks of classical altitude training affects RMR in middle-distance runners. Ten highly trained athletes were recruited for 4 weeks of endurance training undertaking identical programs at either 2200m in Flagstaff, Arizona (ALT, n = 5) or 600m in Canberra, Australia (CON, n = 5). RMR, anthropometry, energy intake, and hemoglobin mass (Hb mass ) were assessed pre- and posttraining. Weekly run distance during the training block was: ALT 96.8 ± 18.3km; CON 103.1 ± 5.6km. A significant interaction for Time*Group was observed for absolute (kJ.day -1 ) (F-statistic, p-value: F (1,8) =13.890, p = .01) and relative RMR (F (1,8) =653.453, p = .003) POST-training. No significant changes in anthropometry were observed in either group. Energy intake was unchanged (mean ± SD of difference, ALT: 195 ± 3921kJ, p = .25; CON: 836 ± 7535kJ, p = .75). A significant main effect for time was demonstrated for total Hb mass (g) (F (1,8) =13.380, p = .01), but no significant interactions were observed for either variable [Total Hb mass (g): F (1,8) =1.706, p = .23; Relative Hb mass (g.kg -1 ): F (1,8) =0.609, p = .46]. These novel findings have important practical application to endurance athletes routinely training at moderate altitude, and those seeking to optimize energy management without compromising training adaptation. Altitude exposure may increase RMR and enhance training adaptation,. During training camps at moderate altitude, an increased energy intake is likely required to support an increased RMR and provide sufficient energy for training and performance.

  8. A randomly-controlled study on the cardiac function at the early stage of return to the plains after short-term exposure to high altitude.

    Directory of Open Access Journals (Sweden)

    Qiquan Zhou

    Full Text Available High altitude acclimatization and adaptation mechanisms have been well clarified, however, high altitude de-adaptation mechanism remains unclear. In this study, we conducted a controlled study on cardiac functions in 96 healthy young male who rapidly entered the high altitude (3700 m and returned to the plains (1500 m after 50 days. Ninety eight healthy male who remained at low altitude were recruited as control group. The mean pulmonary arterial pressure (mPAP, left ventricular ejection fraction (LVEF, left ventricular fraction shortening (LVFS, cardiac function index (Tei index were tested. Levels of serum creatine kinase isoform MB (CK-MB, lactate dehydrogenase isoenzyme-1 (LDH-1, endothelin-1 (ET-1, nitrogen oxide (NO, serum hypoxia-inducible factor-1α (HIF-1α, 8-iso-prostaglandin F(2α (8-iso PGF(2α, superoxide dismutase (SOD and malonaldehyde (MDA were measured at an altitude of 3700 m and 1500 m respectively. The results showed that after short-term exposure to high altitude mPAP and Tei index increased significantly, while LVEF and LVFS decreased significantly. These changes were positively correlated with altitude. On the 15(th day after the subjects returned to low altitude, mPAP, LVEF and LVFS levels returned to the same level as those of the control subjects, but the Tei index in the returned subjects was still significantly higher than that in the control subjects (P<0.01. We also found that changes in Tei index was positively correlated with mPAP, ET-1, HIF-1α and 8-iso PGF(2α levels, and negatively correlated with the level of NO, LVEF, LVFS, CK-MB and LDH-1. These findings suggest that cardiac function de-adapts when returning to the plains after short-term exposure to high altitude and the function recovery takes a relatively long time.

  9. Galling Insects of the Brazilian Páramos: Species Richness and Composition Along High-Altitude Grasslands.

    Science.gov (United States)

    Coelho, Marcel S; Carneiro, Marco Antônio Alves; Branco, Cristina A; Borges, Rafael Augusto Xavier; Fernandes, G Wilson

    2017-12-08

    In this work, we investigated the factors that determine the distribution of galling insects in high-altitude grasslands, locally called 'campos de altitude' of Mantiqueira Range and tested whether 1) richness of galling insects decreases with altitude, 2) galling insect richness increases with plant richness, 3) variation in galling insect diversity is predominantly a consequence of its β component, and 4) turnover is the main mechanism driving the beta diversity of both galling insects and plants. Galling insect richness did not exhibit a negative relationship with altitude, but it did increase with plant richness. The additive partition of regional richness (γ) into its local and beta components showed that local diversity (α) of galling insects and plants was relatively low in relation to regional diversity; the β component incorporated most of the regional diversity. This pattern was also found in the multiscale analysis of the additive partition for galling insects and plants. The beta diversity of galling insects and plants was driven predominantly by the process of turnover and minimally by nesting. The results reported here point out that the spatial distribution of galling insects is best explained by historical factors, such as the distribution of genera and species of key host plants, as well as their relation to habitat, than ecological effects such as hygrothermal stress - here represented by altitude. © The Authors 2017. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  10. Ecophysiological Responses of Three Tree Species to a High-Altitude Environment in the Southeastern Tibetan Plateau

    Directory of Open Access Journals (Sweden)

    Jirui Gong

    2018-01-01

    Full Text Available This paper measured the ecophysiological responses of Populus cathayana Rehd., Salix longistamina C. Wang et P. Y. Fu., and Ulmus pumila L. to high altitude in the Tibetan Plateau based on changes in water relations, gas exchange, and chlorophyll fluorescence. P. cathayana and U. pumila have higher survival rates than S. longistamina, but the latter has highest biomass. S. longistamina has higher water-use efficiency (WUE, lower transpiration rates (E, higher water potential (Ψ, highest light saturation point (LSP and higher photosystem II (PSII photochemistry efficiency (Fv’/Fm’ and non-photochemistry quenching (NPQ than the other species, and is thus adapted to its habitat for afforestation. U. pumila has lower E, light compensation point (LCP, dark respiration (Rd, Fv’/Fm’ and electron transport rate (ETR, with higher Ψ, apparent quantum yield (AQY, net photosynthetic rate (Pn and non-photochemical quenching (NPQ, which helps it maintain water balance and utilize weak light to survive at high altitude. Relative low WUE, Ψ, Rd, NPQ, with high E, Pn, Fv’/Fm’ and biomass, imply that P. cathayana is more suitable for shelterbelt forests than for a semi-arid habitat. These three species can adapt to high-altitude conditions by different physiological mechanisms and morphological characteristics, which can provide a theoretical basis for afforestation and forest management in the Qinghai Tibetan Plateau.

  11. Cerebral pressure-flow relationship in lowlanders and natives at high altitude.

    Science.gov (United States)

    Smirl, Jonathan D; Lucas, Samuel J E; Lewis, Nia C S; duManoir, Gregory R; Dumanior, Gregory R; Smith, Kurt J; Bakker, Akke; Basnyat, Aperna S; Ainslie, Philip N

    2014-02-01

    We investigated if dynamic cerebral pressure-flow relationships in lowlanders are altered at high altitude (HA), differ in HA natives and after return to sea level (SL). Lowlanders were tested at SL (n=16), arrival to 5,050 m, after 2-week acclimatization (with and without end-tidal PO2 normalization), and upon SL return. High-altitude natives (n=16) were tested at 5,050 m. Testing sessions involved resting spontaneous and driven (squat-stand maneuvers at very low (VLF, 0.05 Hz) and low (LF, 0.10 Hz) frequencies) measures to maximize blood pressure (BP) variability and improve assessment of the pressure-flow relationship using transfer function analysis (TFA). Blood flow velocity was assessed in the middle (MCAv) and posterior (PCAv) cerebral arteries. Spontaneous VLF and LF phases were reduced and coherence was elevated with acclimatization to HA (Pflow coupling. However, when BP was driven, both the frequency- and time-domain metrics were unaltered and comparable with HA natives. Acute mountain sickness was unrelated to TFA metrics. In conclusion, the driven cerebral pressure-flow relationship (in both frequency and time domains) is unaltered at 5,050 m in lowlanders and HA natives. Our findings indicate that spontaneous changes in TFA metrics do not necessarily reflect physiologically important alterations in the capacity of the brain to regulate BP.

  12. Characteristics of high altitude oxygen ion energization and outflow as observed by Cluster: a statistical study

    Directory of Open Access Journals (Sweden)

    H. Nilsson

    2006-05-01

    Full Text Available The results of a statistical study of oxygen ion outflow using Cluster data obtained at high altitude above the polar cap is reported. Moment data for both hydrogen ions (H+ and oxygen ions (O+ from 3 years (2001-2003 of spring orbits (January to May have been used. The altitudes covered were mainly in the range 5–12 RE geocentric distance. It was found that O+ is significantly transversely energized at high altitudes, indicated both by high perpendicular temperatures for low magnetic field values as well as by a tendency towards higher perpendicular than parallel temperature distributions for the highest observed temperatures. The O+ parallel bulk velocity increases with altitude in particular for the lowest observed altitude intervals. O+ parallel bulk velocities in excess of 60 km s-1 were found mainly at higher altitudes corresponding to magnetic field strengths of less than 100 nT. For the highest observed parallel bulk velocities of O+ the thermal velocity exceeds the bulk velocity, indicating that the beam-like character of the distribution is lost. The parallel bulk velocity of the H+ and O+ was found to typically be close to the same throughout the observation interval when the H+ bulk velocity was calculated for all pitch-angles. When the H+ bulk velocity was calculated for upward moving particles only the H+ parallel bulk velocity was typically higher than that of O+. The parallel bulk velocity is close to the same for a wide range of relative abundance of the two ion species, including when the O+ ions dominates. The thermal velocity of O+ was always well below that of H+. Thus perpendicular energization that is more effective for O+ takes place, but this is not enough to explain the close to similar parallel velocities. Further

  13. Development and testing of airfoils for high-altitude aircraft

    Science.gov (United States)

    Drela, Mark (Principal Investigator)

    1996-01-01

    Specific tasks included airfoil design; study of airfoil constraints on pullout maneuver; selection of tail airfoils; examination of wing twist; test section instrumentation and layout; and integrated airfoil/heat-exchanger tests. In the course of designing the airfoil, specifically for the APEX test vehicle, extensive studies were made over the Mach and Reynolds number ranges of interest. It is intended to be representative of airfoils required for lightweight aircraft operating at extreme altitudes, which is the primary research objective of the APEX program. Also considered were thickness, pitching moment, and off-design behavior. The maximum ceiling parameter M(exp 2)C(sub L) value achievable by the Apex-16 airfoil was found to be a strong constraint on the pullout maneuver. The NACA 1410 and 2410 airfoils (inverted) were identified as good candidates for the tail, with predictable behavior at low Reynolds numbers and good tolerance to flap deflections. With regards to wing twist, it was decided that a simple flat wing was a reasonable compromise. The test section instrumentation consisted of surface pressure taps, wake rakes, surface-mounted microphones, and skin-friction gauges. Also, a modest wind tunnel test was performed for an integrated airfoil/heat-exchanger configuration, which is currently on Aurora's 'Theseus' aircraft. Although not directly related to the APEX tests, the aerodynamics or heat exchangers has been identified as a crucial aspect of designing high-altitude aircraft and hence is relevant to the ERAST program.

  14. Colorization-Based RGB-White Color Interpolation using Color Filter Array with Randomly Sampled Pattern.

    Science.gov (United States)

    Oh, Paul; Lee, Sukho; Kang, Moon Gi

    2017-06-28

    Recently, several RGB-White (RGBW) color filter arrays (CFAs) have been proposed, which have extra white (W) pixels in the filter array that are highly sensitive. Due to the high sensitivity, the W pixels have better SNR (Signal to Noise Ratio) characteristics than other color pixels in the filter array, especially, in low light conditions. However, most of the RGBW CFAs are designed so that the acquired RGBW pattern image can be converted into the conventional Bayer pattern image, which is then again converted into the final color image by using conventional demosaicing methods, i.e., color interpolation techniques. In this paper, we propose a new RGBW color filter array based on a totally different color interpolation technique, the colorization algorithm. The colorization algorithm was initially proposed for colorizing a gray image into a color image using a small number of color seeds. Here, we adopt this algorithm as a color interpolation technique, so that the RGBW color filter array can be designed with a very large number of W pixels to make the most of the highly sensitive characteristics of the W channel. The resulting RGBW color filter array has a pattern with a large proportion of W pixels, while the small-numbered RGB pixels are randomly distributed over the array. The colorization algorithm makes it possible to reconstruct the colors from such a small number of RGB values. Due to the large proportion of W pixels, the reconstructed color image has a high SNR value, especially higher than those of conventional CFAs in low light condition. Experimental results show that many important information which are not perceived in color images reconstructed with conventional CFAs are perceived in the images reconstructed with the proposed method.

  15. An Undergraduate-Built Prototype Altitude Determination System (PADS) for High Altitude Research Balloons.

    Science.gov (United States)

    Verner, E.; Bruhweiler, F. C.; Abot, J.; Casarotto, V.; Dichoso, J.; Doody, E.; Esteves, F.; Morsch Filho, E.; Gonteski, D.; Lamos, M.; Leo, A.; Mulder, N.; Matubara, F.; Schramm, P.; Silva, R.; Quisberth, J.; Uritsky, G.; Kogut, A.; Lowe, L.; Mirel, P.; Lazear, J.

    2014-12-01

    In this project a multi-disciplinary undergraduate team from CUA, comprising majors in Physics, Mechanical Engineering, Electrical Engineering, and Biology, design, build, test, fly, and analyze the data from a prototype attitude determination system (PADS). The goal of the experiment is to determine if an inexpensive attitude determination system could be built for high altitude research balloons using MEMS gyros. PADS is a NASA funded project, built by students with the cooperation of CUA faculty, Verner, Bruhweiler, and Abot, along with the contributed expertise of researchers and engineers at NASA/GSFC, Kogut, Lowe, Mirel, and Lazear. The project was initiated through a course taught in CUA's School of Engineering, which was followed by a devoted effort by students during the summer of 2014. The project is an experiment to use 18 MEMS gyros, similar to those used in many smartphones, to produce an averaged positional error signal that could be compared with the motion of the fixed optical system as recorded through a string of optical images of stellar fields to be stored on a hard drive flown with the experiment. The optical system, camera microprocessor, and hard drive are enclosed in a pressure vessel, which maintains approximately atmospheric pressure throughout the balloon flight. The experiment uses multiple microprocessors to control the camera exposures, record gyro data, and provide thermal control. CUA students also participated in NASA-led design reviews. Four students traveled to NASA's Columbia Scientific Balloon Facility in Palestine, Texas to integrate PADS into a large balloon gondola containing other experiments, before being shipped, then launched in mid-August at Ft. Sumner, New Mexico. The payload is to fly at a float altitude of 40-45,000 m, and the flight last approximately 15 hours. The payload is to return to earth by parachute and the retrieved data are to be analyzed by CUA undergraduates. A description of the instrument is presented

  16. Classical altitude training.

    Science.gov (United States)

    Friedmann-Bette, B

    2008-08-01

    For more than 40 years, the effects of classical altitude training on sea-level performance have been the subject of many scientific investigations in individual endurance sports. To our knowledge, no studies have been performed in team sports like football. Two well-controlled studies showed that living and training at an altitude of >or=1800-2700 m for 3-4 weeks is superior to equivalent training at sea level in well-trained athletes. Most of the controlled studies with elite athletes did not reveal such an effect. However, the results of some uncontrolled studies indicate that sea-level performance might be enhanced after altitude training also in elite athletes. Whether hypoxia provides an additional stimulus for muscular adaptation, when training is performed with equal intensity compared with sea-level training is not known. There is some evidence for an augmentation of total hemoglobin mass after classical altitude training with duration >or=3 weeks at an altitude >or=2000 m due to altitude acclimatization. Considerable individual variation is observed in the erythropoietic response to hypoxia and in the hypoxia-induced reduction of aerobic performance capacity during training at altitude, both of which are thought to contribute to inter-individual variation in the improvement of sea-level performance after altitude training.

  17. A MID-INFRARED VIEW OF THE HIGH MASS STAR FORMATION REGION W51A

    Energy Technology Data Exchange (ETDEWEB)

    Barbosa, C. L. [Laboratório Nacional de Astrofísica, R. dos Estados Unidos, Bairro das Nações, CEP 37504-364, Itajubá—MG (Brazil); Blum, R. D. [National Optical Astronomy Observatory, Tucson, AZ 85719 (United States); Damineli, A. [Instituto de Astronomia, Geofísica e Ciências Atmosféricas, Universidade de São Paulo, R. do Matão, 1226, Cid. Universitária, São Paulo 05508-900 (Brazil); Conti, P. S. [JILA, University of Colorado, Boulder, CO 80309-0440 (United States); Gusmão, D. M., E-mail: cassio.barbosa@pq.cnpq.br, E-mail: rblum@noao.edu, E-mail: augusto.damineli@iag.usp.br, E-mail: pconti@jila.colorado.edu, E-mail: danilo@univap.br [IP and D—Universidade do Vale do Paraíba, Av. Shishima Hifumi, 2911. São José dos Campos, SP, 12244-000 (Brazil)

    2016-07-01

    In this paper we present the results of a mid-infrared study of G49.5-0.4, or W51A, part of the massive starbirth complex W51. Combining public data from the Spitzer IRAC camera, and Gemini mid-infrared camera T-ReCS at 7.73, 9.69, 12.33, and 24.56 μ m, with a spatial resolution of ∼0.″5, we have identified the mid-infrared counterparts of eight ultracompact H ii regions, showing that two radio sources are deeply embedded in molecular clouds and another is a cloud of ionized gas. From the T-ReCS data we have unveiled the central core of the W51 region, revealing massive young stellar candidates. We modeled the spectral energy distribution of the detected sources. The results suggest that the embedded objects are sources with spectral types ranging from B3 to O5, but the majority of the fits indicate stellar objects with B1 spectral types. We also present an extinction map of IRS 2, showing that a region with lower extinction corresponds to the region where a proposed jet of gas has impacted the foreground cloud. From this map, we also derived the total extinction toward the enigmatic source IRS 2E, which amounts to ∼60 mag in the V band. We calculated the color temperature due to thermal emission of the circumstellar dust of the detected sources; the temperatures are in the interval of ∼100–150 K, which corresponds to the emission of dust located at 0.1 pc from the central source. Finally, we show a possible mid-infrared counterpart of a detected source at millimeter wavelengths that was found by Zapata et al. to be a massive young stellar object undergoing a high accretion rate.

  18. Dietary Recommendations for Cyclists during Altitude Training.

    Science.gov (United States)

    Michalczyk, Małgorzata; Czuba, Miłosz; Zydek, Grzegorz; Zając, Adam; Langfort, Józef

    2016-06-18

    The concept of altitude or hypoxic training is a common practice in cycling. However, several strategies for training regimens have been proposed, like "live high, train high" (LH-TH), "live high, train low" (LH-TL) or "intermittent hypoxic training" (IHT). Each of them combines the effect of acclimatization and different training protocols that require specific nutrition. An appropriate nutrition strategy and adequate hydration can help athletes achieve their fitness and performance goals in this unfriendly environment. In this review, the physiological stress of altitude exposure and training will be discussed, with specific nutrition recommendations for athletes training under such conditions. However, there is little research about the nutrition demands of athletes who train at moderate altitude. Our review considers energetic demands and body mass or body composition changes due to altitude training, including respiratory and urinary water loss under these conditions. Carbohydrate intake recommendations and hydration status are discussed in detail, while iron storage and metabolism is also considered. Last, but not least the risk of increased oxidative stress under hypoxic conditions and antioxidant supplementation suggestions are presented.

  19. Women at Altitude: Effects of Menstrual Cycle Phase and Alpha-Adrenergic Blockade on High Altitude Acclimatization

    National Research Council Canada - National Science Library

    Moore, Lorna

    1998-01-01

    .... Results indicated that the effects of the menstrual cycle were modest. In year 2, we evaluated the safety and efficacy of administering an a-adrenergic blocker and made selected observations during a brief exposure to an altitude of 4300 m...

  20. High altitude headache and acute mountain sickness at moderate elevations in a military population during battalion-level training exercises.

    Science.gov (United States)

    Norris, Jacob N; Viirre, Erik; Aralis, Hilary; Sracic, Michael K; Thomas, Darren; Gertsch, Jeffery H

    2012-08-01

    Few studies have evaluated high altitude headache (HAH) and acute mountain sickness (AMS) in military populations training at moderate (1,500-2,500 m) to high altitudes (>2,500 m). In the current study, researchers interviewed active duty personnel training at Marine Corps Mountain Warfare Training Center. Participants were asked about HAH and AMS symptoms, potential risk factors, and medications used. In a sample of 192 U.S. Navy and Marine Corps personnel, 14.6% reported AMS (Lake Louise Criteria > or = 3) and 28.6% reported HAH. Dehydration and recent arrival at altitude (defined as data collected on days 2-3) were significantly associated with AMS; decreased sleep allowance was significantly associated with HAH. Although ibuprofen/Motrin users were more likely to screen positive for AMS, among AMS-positive participants, ibuprofen/Motrin users had decreased likelihood of reporting robust AMS relative to non-ibuprofen/Motrin users (p altitude. Further, ibuprofen/Motrin may be a reasonable treatment for the symptoms of AMS and HAH, although further study is warranted.