High Production Volume Information System (HPVIS)

Data.gov (United States)

U.S. Environmental Protection Agency — The High Production Volume Information System (HPVIS) provides access to select health and environmental effect information on chemicals that are manufactured in...

High tidal volume ventilation in infant mice.

Science.gov (United States)

Cannizzaro, Vincenzo; Zosky, Graeme R; Hantos, Zoltán; Turner, Debra J; Sly, Peter D

2008-06-30

Infant mice were ventilated with either high tidal volume (V(T)) with zero end-expiratory pressure (HVZ), high V(T) with positive end-expiratory pressure (PEEP) (HVP), or low V(T) with PEEP. Thoracic gas volume (TGV) was determined plethysmographically and low-frequency forced oscillations were used to measure the input impedance of the respiratory system. Inflammatory cells, total protein, and cytokines in bronchoalveolar lavage fluid (BALF) and interleukin-6 (IL-6) in serum were measured as markers of pulmonary and systemic inflammatory response, respectively. Coefficients of tissue damping and tissue elastance increased in all ventilated mice, with the largest rise seen in the HVZ group where TGV rapidly decreased. BALF protein levels increased in the HVP group, whereas serum IL-6 rose in the HVZ group. PEEP keeps the lungs open, but provides high volumes to the entire lungs and induces lung injury. Compared to studies in adult and non-neonatal rodents, infant mice demonstrate a different response to similar ventilation strategies underscoring the need for age-specific animal models.

Best Practices During Hip Arthroscopy: Aggregate Recommendations of High-Volume Surgeons.

Science.gov (United States)

Gupta, Asheesh; Suarez-Ahedo, Carlos; Redmond, John M; Gerhardt, Michael B; Hanypsiak, Bryan; Stake, Christine E; Finch, Nathan A; Domb, Benjamin G

2015-09-01

To survey surgeons who perform a high volume of hip arthroscopy procedures regarding their operative technique, type of procedure, and postoperative management. We conducted a cross-sectional survey of 27 high-volume orthopaedic surgeons specializing in hip arthroscopy to report their preferences and practices related to their operative practice and postoperative rehabilitation protocol. All participants completed the survey in person in an anonymous fashion during a meeting of the American Hip Institute. All surgeons perform hip arthroscopy with the patient in the supine position, accessing the central compartment of the hip initially, using intraoperative fluoroscopy. All surgeons perform labral repair (100%), with the majority performing labral reconstructions (77.8%) and gluteus medius repairs (81.5%). There is variability in the type of anchors used during labral repair. Most surgeons perform capsular closure in most cases (88.9%), inject either intra-articular cortisone or platelet-rich plasma at the conclusion of the procedure (59%), and prescribe a postoperative hip brace for some or all patients (59%). There is considerable variability in rehabilitation protocols. All surgeons routinely prescribe postoperative heterotopic ossification prophylaxis to their patients, with most surgeons (88.9%) prescribing a nonsteroidal anti-inflammatory medication for 3 weeks. Forty percent of the respondents use the modified Harris Hip Score as the most important outcome measure. Consistent practices such as use of intraoperative fluoroscopy, heterotopic ossification prophylaxis, and labral repair skills were identified by surveying 27 hip arthroscopy surgeons at high-volume centers. Most of the surgeons performed routine capsular closure unless underlying conditions precluded capsular release or plication. The survey identified higher variability between surgeons regarding postoperative rehabilitation protocols and use of intra-articular pharmacologic injections at the

Effective moduli of high volume fraction particulate composites

International Nuclear Information System (INIS)

Kwon, P.; Dharan, C.K.H.

1995-01-01

Predictions using current micromechanics theories for the effective moduli of particulate-reinforced composites tend to break down at high volume fractions of the reinforcing phase. The predictions are usually well below experimentally measured values of the Young's modulus for volume fractions exceeding about 0.6. In this paper, the concept of contiguity, which is a measure of phase continuity, is applied to Mori-Tanaka micromechanics theory. It is shown that contiguity of the second phase increases with volume fraction, leading eventually to a reversal in the roles of the inclusion and matrix. In powder metallurgy practice, it is well known that at high volume fractions, sintering and consolidation of the reinforcement make it increasingly continuous and more like the matrix phase, while the former matrix tends to become more like the inclusion phase. The concept of contiguity applied to micromechanics theory results in very good agreement between the predicted Young's modulus and experimental data on tungsten carbide particulate-reinforced cobalt

Study on the High Volume Reduction of Radioactive Wastes

Energy Technology Data Exchange (ETDEWEB)

Kim, Ki Hong; Sik, Kang Il; Seok, Hong Dae [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Ho, Jeon Gil [RADIN Co. Ltd., Daejeon (Korea, Republic of)

2013-10-15

The solidification of radioactive wastes by the mixing method always increases their volume due to the limitation of incorporation ratio (waste/solidification agent). But if the powdered wastes can be compacted as the high density pellets and also the pellets can be filled up in a waste drum as much as possible while solidifying them with a very sticky solidification agent including a void formed in the filling step of pellets, it might be more desirable to reduce the waste volume as compared with the mixing method. So in this study, we designed and manufactured a high volume reduction machine which has the special size and shape of a pellet pocket, which the pellets can be extracted from easily and filled up in a large amount in drum, a pressurizing device to press 2 rolls, and the uniform feeding device of powder to the roll tyre. Some operational parameters which affect the formation of pellets from a powder were investigated, and then the volume reduction of a powder was evaluated. The briquetting machine, popular in general industry, was modified to apply for the volume reduction of the powered radioactive wastes (dried concentrate, sludge, spent ion-exchange resin, ash, depleted uranium powder, and etc.). In this developed high volume reduction machine, the capacity was 25 ∼ 62.5 kg/h at the optimum conditions, and the estimated volume reduction was about 2.95 (2.74/0.93) on the basis of between a powder (bulk density = 0.93 g/cm{sup 3}) and the pellet (2.74 g/cm{sup 3}). But on the basis of 200L drum, the calculated volume reduction was about 1.34 in consideration of a void volume originated in the filling step of the pellets.

High lung volume increases stress failure in pulmonary capillaries

Science.gov (United States)

Fu, Z.; Costello, M. L.; Tsukimoto, K.; Prediletto, R.; Elliott, A. R.; Mathieu-Costello, O.; West, J. B.

1992-01-01

We previously showed that when pulmonary capillaries in anesthetized rabbits are exposed to a transmural pressure (Ptm) of approximately 40 mmHg, stress failure of the walls occurs with disruption of the capillary endothelium, alveolar epithelium, or sometimes all layers. The present study was designed to test whether stress failure occurred more frequently at high than at low lung volumes for the same Ptm. Lungs of anesthetized rabbits were inflated to a transpulmonary pressure of 20 cmH2O, perfused with autologous blood at 32.5 or 2.5 cmH2O Ptm, and fixed by intravascular perfusion. Samples were examined by both transmission and scanning electron microscopy. The results were compared with those of a previous study in which the lung was inflated to a transpulmonary pressure of 5 cmH2O. There was a large increase in the frequency of stress failure of the capillary walls at the higher lung volume. For example, at 32.5 cmH2O Ptm, the number of endothelial breaks per millimeter cell lining was 7.1 +/- 2.2 at the high lung volume compared with 0.7 +/- 0.4 at the low lung volume. The corresponding values for epithelium were 8.5 +/- 1.6 and 0.9 +/- 0.6. Both differences were significant (P less than 0.05). At 52.5 cmH2O Ptm, the results for endothelium were 20.7 +/- 7.6 (high volume) and 7.1 +/- 2.1 (low volume), and the corresponding results for epithelium were 32.8 +/- 11.9 and 11.4 +/- 3.7. At 32.5 cmH2O Ptm, the thickness of the blood-gas barrier was greater at the higher lung volume, consistent with the development of more interstitial edema. Ballooning of the epithelium caused by accumulation of edema fluid between the epithelial cell and its basement membrane was seen at 32.5 and 52.5 cmH2O Ptm. At high lung volume, the breaks tended to be narrower and fewer were oriented perpendicular to the axis of the pulmonary capillaries than at low lung volumes. Transmission and scanning electron microscopy measurements agreed well. Our findings provide a physiological

High Volume Manufacturing and Field Stability of MEMS Products

Science.gov (United States)

Martin, Jack

Low volume MEMS/NEMS production is practical when an attractive concept is implemented with business, manufacturing, packaging, and test support. Moving beyond this to high volume production adds requirements on design, process control, quality, product stability, market size, market maturity, capital investment, and business systems. In a broad sense, this chapter uses a case study approach: It describes and compares the silicon-based MEMS accelerometers, pressure sensors, image projection systems, and gyroscopes that are in high volume production. Although they serve several markets, these businesses have common characteristics. For example, the manufacturing lines use automated semiconductor equipment and standard material sets to make consistent products in large quantities. Standard, well controlled processes are sometimes modified for a MEMS product. However, novel processes that cannot run with standard equipment and material sets are avoided when possible. This reliance on semiconductor tools, as well as the organizational practices required to manufacture clean, particle-free products partially explains why the MEMS market leaders are integrated circuit manufacturers. There are other factors. MEMS and NEMS are enabling technologies, so it can take several years for high volume applications to develop. Indeed, market size is usually a strong function of price. This becomes a vicious circle, because low price requires low cost - a result that is normally achieved only after a product is in high volume production. During the early years, IC companies reduced cost and financial risk by using existing facilities for low volume MEMS production. As a result, product architectures are partially determined by capabilities developed for previous products. This chapter includes a discussion of MEMS product architecture with particular attention to the impact of electronic integration, packaging, and surfaces. Packaging and testing are critical, because they are

An Experimental Study of High Strength-High Volume Fly Ash Concrete for Sustainable Construction Industry

Science.gov (United States)

Kate, Gunavant K.; Thakare, Sunil B., Dr.

2017-08-01

Concrete is the most widely used building material in the construction of infrastructures such as buildings, bridges, highways, dams, and many other facilities. This paper reports the development, the basic idea, the main properties of high strength-high volume fly ash with application in concrete associated with the development and implementation of Sustainable Properties of High Volume Fly Ash Concrete (HVFAC) Mixtures and Early Age Shrinkage and mechanical properties of concrete for 7,28,56 and 90days. Another alternative to make environment-friendly concrete is the development of high strength-high-volume fly ash concrete which is an synthesized from materials of geological origin or by-product materials such as fly ash which is rich in silicon and aluminum. In this paper 6 concrete mixtures were produced to evaluate the effect of key parameters on the mechanical properties of concrete and its behavior. The study key parameters are; binder material content, cement replacement ratios, and the steel fibers used to High Volume Fly Ash mixtures for increasing performance of concrete.

Paul Scherrer Institut Annual Report 2000: General Volume

International Nuclear Information System (INIS)

Salzmann, M.

2001-01-01

The Paul Scherrer Institute is a centre for multidisciplinary research in the natural and engineering sciences. It collaborates closely with universities, other research institutions, technical colleges, and industry, both in Switzerland and abroad. It is the largest research institute in Switzerland, with about 1'200 members of staff. Its particular areas of specialisation are solid-state research and material sciences, elementary particle physics and astrophysics, biology and medicine, and energy and environmental research. This annual report presents an overview of the work performed by the PSI research departments including information on new developments connected with the various accelerators and on the status of the Swiss Light Source project (SLS). Details on the organizational and financial structure of the Institute are also provided

Paul Scherrer Institut Annual Report 2001: General Volume

Energy Technology Data Exchange (ETDEWEB)

Salzmann, M. (ed.)

2002-07-01

The Paul Scherrer Institute is a centre for multidisciplinary research in the natural and engineering sciences. It collaborates closely with universities, other research institutions, technical colleges, and industry, both in Switzerland and abroad. It is the largest research institute in Switzerland, with about 1'200 members of staff. Its particular areas of specialisation are solid-state research and material sciences, elementary particle physics and astrophysics, biology and medicine, and energy and environmental research. This annual report presents an overview of the work performed by the PSI research departments including information on new developments connected with the various accelerators and on the status of the Swiss Light Source project (SLS). Details on the organizational and financial structure of the Institute are also provided.

Paul Scherrer Institut Annual Report 2000: General Volume

Energy Technology Data Exchange (ETDEWEB)

Salzmann, M [ed.

2001-07-01

The Paul Scherrer Institute is a centre for multidisciplinary research in the natural and engineering sciences. It collaborates closely with universities, other research institutions, technical colleges, and industry, both in Switzerland and abroad. It is the largest research institute in Switzerland, with about 1'200 members of staff. Its particular areas of specialisation are solid-state research and material sciences, elementary particle physics and astrophysics, biology and medicine, and energy and environmental research. This annual report presents an overview of the work performed by the PSI research departments including information on new developments connected with the various accelerators and on the status of the Swiss Light Source project (SLS). Details on the organizational and financial structure of the Institute are also provided.

Paul Scherrer Institut Annual Report 1999: General Volume

International Nuclear Information System (INIS)

Salzmann, M.

2000-01-01

The Paul Scherrer Institute is a centre for multidisciplinary research in the natural and engineering sciences. It collaborates closely with universities, other research institutions, technical colleges, and industry, both in Switzerland and abroad. It is the largest research institute in Switzerland, with about 1'200 members of staff. Its particular areas of specialisation are solid-state research and material sciences, elementary particle physics and astrophysics, biology and medicine, and energy and environmental research. This annual report presents an overview of the work performed by the PSI research departments including information on new developments connected with the various accelerators and on the status of the Swiss Light Source project (SLS). Details on the organizational and financial structure of the Institute are also provided

Paul Scherrer Institut Annual Report 1999: General Volume

Energy Technology Data Exchange (ETDEWEB)

Salzmann, M [ed.

2000-07-01

The Paul Scherrer Institute is a centre for multidisciplinary research in the natural and engineering sciences. It collaborates closely with universities, other research institutions, technical colleges, and industry, both in Switzerland and abroad. It is the largest research institute in Switzerland, with about 1'200 members of staff. Its particular areas of specialisation are solid-state research and material sciences, elementary particle physics and astrophysics, biology and medicine, and energy and environmental research. This annual report presents an overview of the work performed by the PSI research departments including information on new developments connected with the various accelerators and on the status of the Swiss Light Source project (SLS). Details on the organizational and financial structure of the Institute are also provided.

Paul Scherrer Institut Annual Report 2001: General Volume

Energy Technology Data Exchange (ETDEWEB)

Salzmann, M [ed.

2002-07-01

The Paul Scherrer Institute is a centre for multidisciplinary research in the natural and engineering sciences. It collaborates closely with universities, other research institutions, technical colleges, and industry, both in Switzerland and abroad. It is the largest research institute in Switzerland, with about 1'200 members of staff. Its particular areas of specialisation are solid-state research and material sciences, elementary particle physics and astrophysics, biology and medicine, and energy and environmental research. This annual report presents an overview of the work performed by the PSI research departments including information on new developments connected with the various accelerators and on the status of the Swiss Light Source project (SLS). Details on the organizational and financial structure of the Institute are also provided.

Paul Scherrer Institut Annual Report 2001: General Volume

International Nuclear Information System (INIS)

Salzmann, M.

2002-01-01

The Paul Scherrer Institute is a centre for multidisciplinary research in the natural and engineering sciences. It collaborates closely with universities, other research institutions, technical colleges, and industry, both in Switzerland and abroad. It is the largest research institute in Switzerland, with about 1'200 members of staff. Its particular areas of specialisation are solid-state research and material sciences, elementary particle physics and astrophysics, biology and medicine, and energy and environmental research. This annual report presents an overview of the work performed by the PSI research departments including information on new developments connected with the various accelerators and on the status of the Swiss Light Source project (SLS). Details on the organizational and financial structure of the Institute are also provided

Paul Scherrer Institut Annual Report 1999: General Volume

Energy Technology Data Exchange (ETDEWEB)

Salzmann, M. [ed.

2000-07-01

The Paul Scherrer Institute is a centre for multidisciplinary research in the natural and engineering sciences. It collaborates closely with universities, other research institutions, technical colleges, and industry, both in Switzerland and abroad. It is the largest research institute in Switzerland, with about 1'200 members of staff. Its particular areas of specialisation are solid-state research and material sciences, elementary particle physics and astrophysics, biology and medicine, and energy and environmental research. This annual report presents an overview of the work performed by the PSI research departments including information on new developments connected with the various accelerators and on the status of the Swiss Light Source project (SLS). Details on the organizational and financial structure of the Institute are also provided.

Paul Scherrer Institut Annual Report 2000: General Volume

Energy Technology Data Exchange (ETDEWEB)

Salzmann, M. [ed.

2001-07-01

The Paul Scherrer Institute is a centre for multidisciplinary research in the natural and engineering sciences. It collaborates closely with universities, other research institutions, technical colleges, and industry, both in Switzerland and abroad. It is the largest research institute in Switzerland, with about 1'200 members of staff. Its particular areas of specialisation are solid-state research and material sciences, elementary particle physics and astrophysics, biology and medicine, and energy and environmental research. This annual report presents an overview of the work performed by the PSI research departments including information on new developments connected with the various accelerators and on the status of the Swiss Light Source project (SLS). Details on the organizational and financial structure of the Institute are also provided.

High volume medical web sites.

Science.gov (United States)

Elliott, B; Elliott, G

2000-01-01

In 1998, 22 million individuals reported surfing the web for medical information, and this number will increase to over 30 million by 2000. Fifteen of the highest volume medical web sites are described in this paper. Sponsorship and/or ownership of the fifteen sites varied. The government sponsors one, and some are the products of well-known educational institutions. One site is supported by a consumer health organization, and the American Medical Association was in the top 15. However, the most common owners are commercial, for-profit businesses. Attributes of the ideal site were categorized, and include a robust privacy and disclosure statement with an emphasis on education and an appropriate role for advertising. The covering of Complementary and Alternative Medicine (CAM) should be in a balanced and unbiased manner. There has to be an emphasis on knowledge based evidence as opposed to testimonials, and sources should be timely and reviewed. Bibliographies of authors need to be available. Hyperlinking to other web resources is valuable, as even the largest of sites cannot come close to covering all of medicine.

High volume improves outcomes: The argument for centralization of rectal cancer surgery.

Science.gov (United States)

Aquina, Christopher T; Probst, Christian P; Becerra, Adan Z; Iannuzzi, James C; Kelly, Kristin N; Hensley, Bradley J; Rickles, Aaron S; Noyes, Katia; Fleming, Fergal J; Monson, John R T

2016-03-01

Centralization of care to "centers of excellence" in Europe has led to improved oncologic outcomes; however, little is known regarding the impact of nonmandated regionalization of rectal cancer care in the United States. The Statewide Planning and Research Cooperative System (SPARCS) was queried for elective abdominoperineal and low anterior resections for rectal cancer from 2000 to 2011 in New York with the use of International Classification of Diseases, Ninth Revision codes. Surgeon volume and hospital volume were grouped into quartiles, and high-volume surgeons (≥ 10 resections/year) and hospitals (≥ 25 resections/year) were defined as the top quartile of annual caseload of rectal cancer resection and compared with the bottom 3 quartiles during analyses. Bivariate and multilevel regression analyses were performed to assess factors associated with restorative procedures, 30-day mortality, and temporal trends in these endpoints. Among 7,798 rectal cancer resections, the overall rate of no-restorative proctectomy and 30-day mortality decreased by 7.7% and 1.2%, respectively, from 2000 to 2011. In addition, there was a linear increase in the proportion of cases performed by both high-volume surgeons and high-volume hospitals and a decrease in the number of surgeons and hospitals performing rectal cancer surgery. High-volume surgeons at high-volume hospitals were associated independently with both less nonrestorative proctectomies (odds ratio 0.65, 95% confidence interval 0.48-0.89) and mortality (odds ratio 0.43, 95% confidence interval 0.21-0.87) rates. No patterns of significant improvement within the volume strata of the surgeon and hospitals were observed over time. This study suggests that the current trend toward regionalization of rectal cancer care to high-volume surgeons and high-volume centers has led to improved outcomes. These findings have implications regarding the policy of health care delivery in the United States, supporting referral to high-volume

Unsupervised Learning Through Randomized Algorithms for High-Volume High-Velocity Data (ULTRA-HV).

Energy Technology Data Exchange (ETDEWEB)

Pinar, Ali [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Kolda, Tamara G. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Carlberg, Kevin Thomas [Wake Forest Univ., Winston-Salem, MA (United States); Ballard, Grey [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Mahoney, Michael [Univ. of California, Berkeley, CA (United States)

2018-01-01

Through long-term investments in computing, algorithms, facilities, and instrumentation, DOE is an established leader in massive-scale, high-fidelity simulations, as well as science-leading experimentation. In both cases, DOE is generating more data than it can analyze and the problem is intensifying quickly. The need for advanced algorithms that can automatically convert the abundance of data into a wealth of useful information by discovering hidden structures is well recognized. Such efforts however, are hindered by the massive volume of the data and its high velocity. Here, the challenge is developing unsupervised learning methods to discover hidden structure in high-volume, high-velocity data.

Ribbon scanning confocal for high-speed high-resolution volume imaging of brain.

Directory of Open Access Journals (Sweden)

Alan M Watson

Full Text Available Whole-brain imaging is becoming a fundamental means of experimental insight; however, achieving subcellular resolution imagery in a reasonable time window has not been possible. We describe the first application of multicolor ribbon scanning confocal methods to collect high-resolution volume images of chemically cleared brains. We demonstrate that ribbon scanning collects images over ten times faster than conventional high speed confocal systems but with equivalent spectral and spatial resolution. Further, using this technology, we reconstruct large volumes of mouse brain infected with encephalitic alphaviruses and demonstrate that regions of the brain with abundant viral replication were inaccessible to vascular perfusion. This reveals that the destruction or collapse of large regions of brain micro vasculature may contribute to the severe disease caused by Venezuelan equine encephalitis virus. Visualization of this fundamental impact of infection would not be possible without sampling at subcellular resolution within large brain volumes.

A comparative study of self-consolidating concretes incorporating high-volume natural pozzolan or high-volume fly ash

KAUST Repository

Celik, Kemal; Meral, Cagla; Mancio, Mauricio; Mehta, P. Kumar; Monteiro, Paulo J.M.

2014-01-01

The purpose of this study is to compare the effects of Portland cement replacement on the strength and durability of self-consolidating concretes (SSC). The two replacement materials used are high-volume natural pozzolan (HVNP), a Saudi Arabian aluminum-silica rich basaltic glass and high-volume Class-F fly ash (HVFAF), from Jim Bridger Power Plant, Wyoming, US. As an extension of the study, limestone filler (LF) is also used to replace Portland cement, alongside HVNP or HVFAF, forming ternary blends. Along with compressive strength tests, non-steady state chloride migration and gas permeability tests were performed, as durability indicators, on SCC specimens. The results were compared to two reference concretes; 100% ordinary Portland cement (OPC) and 85% OPC - 15% LF by mass. The HVNP and HVFAF concrete mixes showed strength and durability results comparable to those of the reference concretes; identifying that both can effectively be used to produce low-cost and environmental friendly SCC. © 2013 Elsevier Ltd. All rights reserved.

A comparative study of self-consolidating concretes incorporating high-volume natural pozzolan or high-volume fly ash

KAUST Repository

Celik, Kemal

2014-09-01

The purpose of this study is to compare the effects of Portland cement replacement on the strength and durability of self-consolidating concretes (SSC). The two replacement materials used are high-volume natural pozzolan (HVNP), a Saudi Arabian aluminum-silica rich basaltic glass and high-volume Class-F fly ash (HVFAF), from Jim Bridger Power Plant, Wyoming, US. As an extension of the study, limestone filler (LF) is also used to replace Portland cement, alongside HVNP or HVFAF, forming ternary blends. Along with compressive strength tests, non-steady state chloride migration and gas permeability tests were performed, as durability indicators, on SCC specimens. The results were compared to two reference concretes; 100% ordinary Portland cement (OPC) and 85% OPC - 15% LF by mass. The HVNP and HVFAF concrete mixes showed strength and durability results comparable to those of the reference concretes; identifying that both can effectively be used to produce low-cost and environmental friendly SCC. © 2013 Elsevier Ltd. All rights reserved.

High speed analysis of high pressure combustion in a constant volume cell

NARCIS (Netherlands)

Frijters, P.J.M.; Klein-Douwel, R.J.H.; Manski, S.S.; Somers, L.M.T.; Baert, R.S.G.; Dias, V.

2005-01-01

A combustion process with N2, O2 and C2H4 as fuel used in an opticallyaccessible, high pressure, high temperature, constant volume cell forresearch on diesel fuel spray formation, is studied. The flame frontspeed Vf,HS is determined using high speed imaging. The pressure traceof the combustion

Indigenous high volume air sampler

International Nuclear Information System (INIS)

Kotrappa, P.; Setty, N.P.N.; Raghunath, B.; Sivasubrahmanyam, P.S.

1978-01-01

A high volume air sampler for use in assessing concentrations of low levels of air borne particulates has been fabricated. The sampler will be of use in radioactive installations, conventional industries and environmental pollution analysis. It is comparable in performance with the imported Staplex air samplers. A turbine and motor system similar to the one found in conventional vacuum cleaners is used in its design. The sampler units can be produced in large numbers. (M.G.B.)

Indian Institute of Technology, Guwahat

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 10; Issue 1. Refresher Course in Experimental Physics – Indian Institute of Technology, ... Information and Announcements Volume 10 Issue 1 January 2005 pp 96-96 ...

SCC with high volume of fly ash content

Directory of Open Access Journals (Sweden)

Bakhrakh Anton

2017-01-01

Full Text Available Self-compacting concrete is a very perspective building material. It provides great benefits during the construction of heavily reinforced buildings. SCC has outstanding properties such as high flowability, dense structure and high strength due to specific quality of aggregates, fillers, their proportion in mix, use of polycarboxylate-based superplasticizers. Main disadvantages of SCC are high price and the difficulty of obtaining a proper mix. Use of fillers, such as fly ash type F, is a way to make SCC cheaper by replacing part of cement. Fly ash also provides some technological and operating advantages. In this paper the influence of high volume (60% from cement fly ash type F on the properties of concrete mixture and hardened concrete is investigated. The result of the work shows the possibility of reduction the cost of SCC using ordinary fillers and high amount of fly ash. The investigated SCC has low speed of hardening (7-day compressive strength at the range of 41.8 MPa and high volume of entrained air content (3.5%.

Inter fraction variations in rectum and bladder volumes and dose distributions during high dose rate brachytherapy treatment of the uterine cervix investigated by repetitive CT-examinations

International Nuclear Information System (INIS)

Hellebust, Taran Paulsen; Dale, Einar; Skjoensberg, Ane; Olsen, Dag Rune

2001-01-01

Purpose: To evaluate variation of dose to organs at risk for patients receiving fractionated high dose rate gynaecological brachytherapy by using CT-based 3D treatment planning and dose-volume histograms (DVH). Materials and methods: Fourteen patients with cancer of the uterine cervix underwent three to six CT examinations (mean 4.9) during their course of high-dose-rate brachytherapy using radiographically compatible applicators. The rectal and bladder walls were delineated and DVHs were calculated. Results: Inter fraction variation of the bladder volume (CV mean =44.1%) was significantly larger than the inter fraction variation of the mean dose (CV mean =19.9%, P=0.005) and the maximum dose (CV mean =17.5%, P=0.003) of the bladder wall. The same trend was seen for rectum, although the figures were not significantly different. Performing CT examinations at four of seven brachytherapy fractions reduced the uncertainty to 4 and 7% for the bladder and rectal doses, respectively. A linear regression analysis showed a significant, negative relationship between time after treatment start and the whole bladder volume (P=0.018), whereas no correlation was found for the rectum. For both rectum and bladder a linear regression analysis revealed a significant, negative relationship between the whole volume and median dose (P<0.05). Conclusion: Preferably a CT examination should be provided at every fraction. However, this is logistically unfeasible in most institutions. To obtain reliable DVHs the patients will in the future undergo 3-4 CT examinations during the course of brachytherapy at our institution. Since this study showed an association between large bladder volumes and dose reductions, the patients will be treated with a standardized bladder volume

High resolution gas volume change sensor

International Nuclear Information System (INIS)

Dirckx, Joris J. J.; Aernouts, Jef E. F.; Aerts, Johan R. M.

2007-01-01

Changes of gas quantity in a system can be measured either by measuring pressure changes or by measuring volume changes. As sensitive pressure sensors are readily available, pressure change is the commonly used technique. In many physiologic systems, however, buildup of pressure influences the gas exchange mechanisms, thus changing the gas quantity change rate. If one wants to study the gas flow in or out of a biological gas pocket, measurements need to be done at constant pressure. In this article we present a highly sensitive sensor for quantitative measurements of gas volume change at constant pressure. The sensor is based on optical detection of the movement of a droplet of fluid enclosed in a capillary. The device is easy to use and delivers gas volume data at a rate of more than 15 measurements/s and a resolution better than 0.06 μl. At the onset of a gas quantity change the sensor shows a small pressure artifact of less than 15 Pa, and at constant change rates the pressure artifact is smaller than 10 Pa or 0.01% of ambient pressure

[Conceptualization of knowledge management in medium and high complexity health institutions].

Science.gov (United States)

Arboleda-Posada, Gladys I

2016-06-01

Objective To identify the familiarization, conceptualization and incorporation of employees of medium and high complexity health institutions in the Valle de Aburrá, Colombia into the strategic knowledge management platform in 2011. Methodology Cross sectional study. The study was carried out by applying surveys to 224 employees to assess knowledge management. The population included staff who working in the Health Providing Institutions (IPS) of high (52) and medium complexity (322) in the Valle de Aburrá in 2011. In both the public and private institutions surveyed, 38.8 % of the respondents said they were not familiar with knowledge management. Among those who had administrative training, the ignorance was less than among care workers. It was also noted that as the level of education increased, knowledge of the concept was greater. A high proportion (65.2 % ) of respondents placed the concept in line with the creation, organization, storage, retrieval, transfer and application of knowledge systematically. 78.7 % of respondents from public institutions said that knowledge management was part of the strategic platform of the institution. 58.3 % from private institutions said the same. Conclusions In general terms the concept of knowledge management is not well conceived or familiar to the staff working in these institutions. The study confirmed a lack of empowerment in the field to promote the development of new ideas and to ensure that they become service innovations or processes that contribute to the development of institutional knowledge.

The Wildlife Institute of India

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 1; Issue 9. Careers in Nature Conservation: The Wildlife Institute of India. T R Shankar Raman. Information and Announcements Volume 1 Issue 9 September 1996 pp 89-93 ...

Towards high-resolution positron emission tomography for small volumes

International Nuclear Information System (INIS)

McKee, B.T.A.

1982-01-01

Some arguments are made regarding the medical usefulness of high spatial resolution in positron imaging, even if limited to small imaged volumes. Then the intrinsic limitations to spatial resolution in positron imaging are discussed. The project to build a small-volume, high resolution animal research prototype (SHARP) positron imaging system is described. The components of the system, particularly the detectors, are presented and brief mention is made of data acquisition and image reconstruction methods. Finally, some preliminary imaging results are presented; a pair of isolated point sources and 18 F in the bones of a rabbit. Although the detector system is not fully completed, these first results indicate that the goals of high sensitivity and high resolution (4 mm) have been realized. (Auth.)

Effect of high-volume systematic local infiltration analgesia in Caesarean section

DEFF Research Database (Denmark)

Larsen, Klaus Richter; Kristensen, B B; Rasmussen, M A

2015-01-01

BACKGROUND: Pain after Caesarean section is often treated with opioids with a risk of side effects. Wound infiltration with local anaesthetics is effective and has few side effects, but volume vs. dose concentration has not been examined. METHODS: Ninety patients scheduled for elective Caesarean...... found concerning time spent in the PACU, to first mobilisation or in number of women with nausea/vomiting (P ≥ 0.05). No complications related to ropivacaine were observed. CONCLUSIONS: Systematic infiltration with a high concentration, low volume compared with low concentration, high volume showed...

Read-only high accuracy volume holographic optical correlator

Science.gov (United States)

Zhao, Tian; Li, Jingming; Cao, Liangcai; He, Qingsheng; Jin, Guofan

2011-10-01

A read-only volume holographic correlator (VHC) is proposed. After the recording of all of the correlation database pages by angular multiplexing, a stand-alone read-only high accuracy VHC will be separated from the VHC recording facilities which include the high-power laser and the angular multiplexing system. The stand-alone VHC has its own low power readout laser and very compact and simple structure. Since there are two lasers that are employed for recording and readout, respectively, the optical alignment tolerance of the laser illumination on the SLM is very sensitive. The twodimensional angular tolerance is analyzed based on the theoretical model of the volume holographic correlator. The experimental demonstration of the proposed read-only VHC is introduced and discussed.

Improved Short-Term Outcomes following Orthognathic Surgery Are Associated with High-Volume Centers.

Science.gov (United States)

Berlin, Nicholas L; Tuggle, Charles T; Steinbacher, Derek M

2016-08-01

Previous studies assessing outcomes following orthognathic surgery rely primarily on single-center/surgeon experience. In addition to issues of generalizability, these studies are limited in evaluating the effect of operative volume on patient outcomes. Orthognathic procedures were identified in the 1999 to 2011 Healthcare Cost and Utilization Project Nationwide Inpatient Sample. Outcomes included occurrence of any in-hospital complication, extended length of stay (>2 days), and increased costs (>$10,784). High-volume hospitals were defined as the 90th percentile of case volume or higher (>31 cases/year). Univariate and multivariate analyses were conducted to identify independent predictors of outcomes. Trend analyses were performed to assess changes in the annual rate of patients treated at high-volume hospitals over the study period. Among 101,692 orthognathic surgery patients, 19.6 percent underwent concurrent ancillary procedures (i.e., genioplasty, rhinoplasty, or septoplasty), and 37.6 percent underwent double-jaw surgery. Fifty-three percent were treated at high-volume hospitals. High-volume hospitals more often performed ancillary procedures (21.4 percent versus 17.4 percent; p surgery (41.3 percent versus 33.4 percent; p orthognathic cases nationwide are performed at a small number of high-volume hospitals. These hospitals discharge patients earlier, perform more complex procedures, and have fewer complications. Risk, III.

Low-volume high-intensity swim training is superior to high-volume low-intensity training in relation to insulin sensitivity and glucose control in inactive middle-aged women.

Science.gov (United States)

Connolly, Luke J; Nordsborg, Nikolai B; Nyberg, Michael; Weihe, Pál; Krustrup, Peter; Mohr, Magni

2016-10-01

We tested the hypothesis that low-volume high-intensity swimming has a larger impact on insulin sensitivity and glucose control than high-volume low-intensity swimming in inactive premenopausal women with mild hypertension. Sixty-two untrained premenopausal women were randomised to an inactive control (n = 20; CON), a high-intensity low-volume (n = 21; HIT) or a low-intensity high-volume (n = 21; LIT) training group. During the 15-week intervention period, HIT performed 3 weekly 6-10 × 30-s all-out swimming intervals (average heart rate (HR) = 86 ± 3 % HRmax) interspersed by 2-min recovery periods and LIT swam continuously for 1 h at low intensity (average HR = 73 ± 3 % HRmax). Fasting blood samples were taken and an oral glucose tolerance test (OGTT) was conducted pre- and post-intervention. After HIT, resting plasma [insulin] was lowered (17 ± 34 %; P high-intensity intermittent swimming is an effective and time-efficient training strategy for improving insulin sensitivity, glucose control and biomarkers of vascular function in inactive, middle-aged mildly hypertensive women.

High volume tidal or current flow harnessing system

Energy Technology Data Exchange (ETDEWEB)

Gorlov, A.M.

1984-08-07

Apparatus permitting the utilization of large volumes of water in the harnessing and extracting of a portion of the power generated by the rise and fall of ocean tides, ocean currents, or flowing rivers includes the provision of a dam, and a specialized single cavity chamber of limited size as compared with the water head enclosed by the dam, and an extremely high volume gating system in which all or nearly all of the water between the high and low levels on either side of the dam is cyclically gated through the single chamber from one side of the dam to the other so as to alternately provide positive air pressure and a partial vacuum within the single chamber. In one embodiment, the specialized chamber has a barrier at the bottom which divides the bottom of the chamber in half, large ports at the bottom of the chamber to permit inflow and outflow of high volumes of water, and ganged structures having a higher total area than that of corresponding ports, in which the structures form sluice gates to selectively seal off and open different sets of ports. In another embodiment, a single chamber is used without a barrier. In this embodiment, vertical sluice gates are used which may be activated automatically by pressures acting on the sluice gates as a result of ingested and expelled water.

High-level waste borosilicate glass: A compendium of corrosion characteristics. Volume 2

International Nuclear Information System (INIS)

Cunnane, J.C.

1994-03-01

The objective of this document is to summarize scientific information pertinent to evaluating the extent to which high-level waste borosilicate glass corrosion and the associated radionuclide release processes are understood for the range of environmental conditions to which waste glass may be exposed in service. Alteration processes occurring within the bulk of the glass (e.g., devitrification and radiation-induced changes) are discussed insofar as they affect glass corrosion.This document is organized into three volumes. Volumes I and II represent a tiered set of information intended for somewhat different audiences. Volume I is intended to provide an overview of waste glass corrosion, and Volume 11 is intended to provide additional experimental details on experimental factors that influence waste glass corrosion. Volume III contains a bibliography of glass corrosion studies, including studies that are not cited in Volumes I and II. Volume I is intended for managers, decision makers, and modelers, the combined set of Volumes I, II, and III is intended for scientists and engineers working in the field of high-level waste

High-level waste borosilicate glass: A compendium of corrosion characteristics. Volume 2

Energy Technology Data Exchange (ETDEWEB)

Cunnane, J.C. [comp.; Bates, J.K.; Bradley, C.R. [Argonne National Lab., IL (United States)] [and others

1994-03-01

The objective of this document is to summarize scientific information pertinent to evaluating the extent to which high-level waste borosilicate glass corrosion and the associated radionuclide release processes are understood for the range of environmental conditions to which waste glass may be exposed in service. Alteration processes occurring within the bulk of the glass (e.g., devitrification and radiation-induced changes) are discussed insofar as they affect glass corrosion.This document is organized into three volumes. Volumes I and II represent a tiered set of information intended for somewhat different audiences. Volume I is intended to provide an overview of waste glass corrosion, and Volume 11 is intended to provide additional experimental details on experimental factors that influence waste glass corrosion. Volume III contains a bibliography of glass corrosion studies, including studies that are not cited in Volumes I and II. Volume I is intended for managers, decision makers, and modelers, the combined set of Volumes I, II, and III is intended for scientists and engineers working in the field of high-level waste.

Assessing the quality of the volume-outcome relationship in uro-oncology.

Science.gov (United States)

Mayer, Erik K; Purkayastha, Sanjay; Athanasiou, Thanos; Darzi, Ara; Vale, Justin A

2009-02-01

To assess systematically the quality of evidence for the volume-outcome relationship in uro-oncology, and thus facilitate the formulating of health policy within this speciality, as 'Implementation of Improving Outcome Guidance' has led to centralization of uro-oncology based on published studies that have supported a 'higher volume-better outcome' relationship, but improved awareness of methodological drawbacks in health service research has questioned the strength of this proposed volume-outcome relationship. We systematically searched previous relevant reports and extracted all articles from 1980 onwards assessing the volume-outcome relationship for cystectomy, prostatectomy and nephrectomy at the institution and/or surgeon level. Studies were assessed for their methodological quality using a previously validated rating system. Where possible, meta-analytical methods were used to calculate overall differences in outcome measures between low and high volume healthcare providers. In all, 22 studies were included in the final analysis; 19 of these were published in the last 5 years. Only four studies appropriately explored the effect of both the institution and surgeon volume on outcome measures. Mortality and length of stay were the most frequently measured outcomes. The median total quality scores within each of the operation types were 8.5, 9 and 8 for cystectomy, prostatectomy and nephrectomy, respectively (possible maximum score 18). Random-effects modelling showed a higher risk of mortality in low-volume institutions than in higher-volume institutions for both cystectomy and nephrectomy (odds ratio 1.88, 95% confidence interval 1.54-2.29, and 1.28, 1.10-1.49, respectively). The methodological quality of volume-outcome research as applied to cystectomy, prostatectomy and nephrectomy is only modest at best. Accepting several limitations, pooled analysis confirms a higher-volume, lower-mortality relationship for cystectomy and nephrectomy. Future research should

The relationship between patient volume and mortality in American trauma centres: a systematic review of the evidence.

Science.gov (United States)

Caputo, Lisa M; Salottolo, Kristin M; Slone, Denetta Sue; Mains, Charles W; Bar-Or, David

2014-03-01

To synthesise published and unpublished findings examining the relationship between institutional trauma centre volume or trauma patient volume per surgeon and mortality. Evidence on the relationship between patient volume and survival in trauma patients is inconclusive in the literature and remains controversial. A literature search was performed to identify studies published between 1976 and 2013 via MEDLINE (Pubmed) and the Cumulative Index to Nursing and Allied Health Literature (EbscoHost) as well as footnote chasing. Abstracts from appropriate conferences and ProQuest Dissertations and Theses were also searched. Inclusion criteria required studies to be original research published in English that examined the relationship between mortality and either institutional or per surgeon volume in American trauma centres. We employed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Statement checklist and flowchart. The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach was employed to rate the quality of the evidence. Of 1392 studies reviewed, 19 studies met defined inclusion criteria; all studies were retrospective. The definition of volume was heterogeneous across the studies. Patient population and analysis methods also varied across the studies. Sixteen studies (84%) examined the relationship between institutional trauma centre volume and mortality. Of the 16 studies, 12 examined the volume of severely injured patients and eight examined overall trauma patient volume. High institutional volume was associated with at least somewhat improved mortality in ten of 16 studies (63%); however, nearly half of these studies found only some subpopulations experienced benefits. In the remaining six studies, volume was not associated with any benefits. Four studies (25%) analysed the impact of surgeon volume on mortality. High volume per surgeon was associated with improved mortality in only one of four studies

High energy physics: Experimental, theoretical and phenomenology institute

International Nuclear Information System (INIS)

Barger, V.; Camerini, U.; Carlsmith, D.; Durand, B.; Durand, L.; Erwin, A.; Fry, W.; Goebel, C.; Halzen, F.; Loveless, R.; March, R.; Morse, R.; Olsson, M.; Pondrom, L.; Prepost, R.; Reeder, D.; Sheaff, M.; Smith, W.; Thompson, M.; Wu, S.L.

1991-01-01

This report discusses research in the following task: hadron physics at Fermilab; Lepton hadron scattering; electromagnetic ampersand weak interactions at the Stanford Linear Accelerator Center - SLAC; hyperon beam program - hadroproduction of heavy beam flavors at Fermilab; ultra high energy colliding beam physics; Institute for high energy physics phenomenology; weak ampersand electromagnetic interactions using PETRA at DESY ampersand LEP at CERN; theoretical high energy physics; DUMAND; study of ultra high energy gamma rays; data analysis facility; and R ampersand D for major subsystems for the SSC detectors

The deflation limb of the pressure-volume relationship in infants during high-frequency ventilation.

Science.gov (United States)

Tingay, David G; Mills, John F; Morley, Colin J; Pellicano, Anastasia; Dargaville, Peter A

2006-02-15

The importance of applying high-frequency oscillatory ventilation with a high lung volume strategy in infants is well established. Currently, a lack of reliable methods for assessing lung volume limits clinicians' ability to achieve the optimum volume range. To map the pressure-volume relationship of the lung during high-frequency oscillatory ventilation in infants, to determine at what point ventilation is being applied clinically, and to describe the relationship between airway pressure, lung volume, and oxygenation. In 12 infants, a partial inflation limb and the deflation limb of the pressure-volume relationship were mapped using a quasi-static lung volume optimization maneuver. This involved stepwise airway pressure increments to total lung capacity, followed by decrements until the closing pressure of the lung was identified. Lung volume and oxygen saturation were recorded at each airway pressure. Lung volume was measured using respiratory inductive plethysmography. A distinct deflation limb could be mapped in each infant. Overall, oxygenation and lung volume were improved by applying ventilation on the deflation limb. Maximal lung volume and oxygenation occurred on the deflation limb at a mean airway pressure of 3 and 5 cm H(2)O below the airway pressure approximating total lung capacity, respectively. Using current ventilation strategies, all infants were being ventilated near the inflation limb. It is possible to delineate the deflation limb in infants receiving high-frequency oscillatory ventilation; in doing so, greater lung volume and oxygenation can be achieved, often at lower airway pressures.

Compression Behavior of Confined Columns with High-Volume Fly Ash Concrete

Directory of Open Access Journals (Sweden)

Sung-Won Yoo

2017-01-01

Full Text Available The use of fly ash in ordinary concrete provides practical benefits to concrete structures, such as a gain in long-term strength, reduced hydration heat, improved resistance to chloride, and enhanced workability. However, few studies with high-volume fly ash (HVFA concrete have been conducted that focus on the structural applications such as a column. Thus, there is a need to promote field applications of HVFA concrete as a sustainable construction material. To this end, this study investigated the compressive behavior of reinforced concrete columns that contain HVFA with a 50 percent replacement rate. Six columns were fabricated for this study. The study variables were the HVFA replacement rate, tied steel ratio, and tie steel spacing. The computed ultimate strength by the American Concrete Institute (ACI code conservatively predicted the measured values, and, thus, the existing equation in the ACI code is feasible for confined RC columns that contain HVFA. In addition, an analysis model was calibrated based on the experimental results and is recommended for predicting the stress-strain relationship of confined reinforced concrete columns that contain HVFA.

Deep Learning Algorithm for Auto-Delineation of High-Risk Oropharyngeal Clinical Target Volumes With Built-In Dice Similarity Coefficient Parameter Optimization Function.

Science.gov (United States)

Cardenas, Carlos E; McCarroll, Rachel E; Court, Laurence E; Elgohari, Baher A; Elhalawani, Hesham; Fuller, Clifton D; Kamal, Mona J; Meheissen, Mohamed A M; Mohamed, Abdallah S R; Rao, Arvind; Williams, Bowman; Wong, Andrew; Yang, Jinzhong; Aristophanous, Michalis

2018-06-01

Automating and standardizing the contouring of clinical target volumes (CTVs) can reduce interphysician variability, which is one of the largest sources of uncertainty in head and neck radiation therapy. In addition to using uniform margin expansions to auto-delineate high-risk CTVs, very little work has been performed to provide patient- and disease-specific high-risk CTVs. The aim of the present study was to develop a deep neural network for the auto-delineation of high-risk CTVs. Fifty-two oropharyngeal cancer patients were selected for the present study. All patients were treated at The University of Texas MD Anderson Cancer Center from January 2006 to August 2010 and had previously contoured gross tumor volumes and CTVs. We developed a deep learning algorithm using deep auto-encoders to identify physician contouring patterns at our institution. These models use distance map information from surrounding anatomic structures and the gross tumor volume as input parameters and conduct voxel-based classification to identify voxels that are part of the high-risk CTV. In addition, we developed a novel probability threshold selection function, based on the Dice similarity coefficient (DSC), to improve the generalization of the predicted volumes. The DSC-based function is implemented during an inner cross-validation loop, and probability thresholds are selected a priori during model parameter optimization. We performed a volumetric comparison between the predicted and manually contoured volumes to assess our model. The predicted volumes had a median DSC value of 0.81 (range 0.62-0.90), median mean surface distance of 2.8 mm (range 1.6-5.5), and median 95th Hausdorff distance of 7.5 mm (range 4.7-17.9) when comparing our predicted high-risk CTVs with the physician manual contours. These predicted high-risk CTVs provided close agreement to the ground-truth compared with current interobserver variability. The predicted contours could be implemented clinically, with only

High-volume recycled materials for sustainable pavement construction.

Science.gov (United States)

2017-05-01

The main objective of this research is to evaluate the feasibility of using high-volume recycled materials for concrete production in rigid pavement. The goal was to replace 50% of the solids with recycled materials and industrial by-products. The pe...

The journal that spawned an institution

International Nuclear Information System (INIS)

Anon.

1979-01-01

When in 1958 an announcement was made in the Nuclear Energy Engineer that a foundling-committee had been set up to form the Institution of Nuclear Engineers, the journal was already into volume 12. Five members of the Institution's Publishing Committee here give their impressions of the Journal during the first five formative years of the Institution. (U.K.)

Volumizing effects of a smooth, highly cohesive, viscous 20-mg/mL hyaluronic acid volumizing filler: prospective European study

Directory of Open Access Journals (Sweden)

Hoffmann Klaus

2009-08-01

Full Text Available Abstract Background Facial volume loss contributes significantly to facial aging. The 20-mg/mL hyaluronic acid (HA formulation used in this study is a smooth, highly cohesive, viscous, fully reversible, volumizing filler indicated to restore facial volume. This first prospective study evaluated use in current aesthetic clinical practice. Methods A pan-European evaluation conducted under guidelines of the World Association of Opinion and Marketing Research, the trial comprised a baseline visit (visit 1 and a follow-up (visit 2 at 14 ± 7 days posttreatment. Physicians photographed patients at each visit. Each patient was treated with the 20-mg/mL HA volumizing filler as supplied in standard packaging. Procedural details, aesthetic outcomes, safety, and physician and patient ratings of their experience were recorded. Results Fifteen physicians and 70 patients (91% female; mean age: 50 years participated. Mean volume loss at baseline was 3.7 (moderate on the Facial Volume Loss Scale. Local anesthesia was used in 64.3% of cases. Most injections (85% were administered with needles rather than cannulas. Of the 208 injections, 59% were in the malar region, primarily above the periosteum. Subcutaneous injections were most common for other sites. The mean total injection volume per patient was 4.6 mL. The mean volume loss score declined significantly (P Conclusion The 20-mg/mL smooth, highly cohesive, viscous, volumizing HA filler was effective, well tolerated, and easy to use in current clinical practice. Participants were very likely to recommend this product to colleagues and friends, and patients would be very or quite likely to request this product for future treatments.

llonnl institution of (6rtnt Jnritain.

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 2; Issue 12. Royal Institution of Great Britain - Weekly Evening Meeting. Joseph John Thomson. Classics Volume 2 Issue 12 December 1997 pp 92-106. Fulltext. Click here to view fulltext PDF. Permanent link:

Powder metallurgical high performance materials. Proceedings. Volume 4: late papers

Energy Technology Data Exchange (ETDEWEB)

Kneringer, G; Roedhammer, P; Wildner, H [eds.

2001-07-01

This is the fourth volume (late papers) of the 15th International Plansee seminar 2001 which general theme was 'Powder metallurgical high performance materials'. The seminar looked beyond the refractory metals and cemented carbides, which remain as its focus, to novel classes of materials, such as intermetallic compounds, with potential for high temperature applications. This volume 4 contains papers dealing with high performance P/M metals (ITER and fusion reactors, solid targets, materials microstructure, novel alloys, etc.), P/M hard materials ( production and characterization, tungsten carbides, titanium carbides, microstructural design, coatings composition and performance, etc.) and general topics. From 37 papers 24 correspond to INIS subject scope and they were indexed separately. (nevyjel)

Powder metallurgical high performance materials. Proceedings. Volume 4: late papers

International Nuclear Information System (INIS)

Kneringer, G.; Roedhammer, P.; Wildner, H.

2001-01-01

This is the fourth volume (late papers) of the 15th International Plansee seminar 2001 which general theme was 'Powder metallurgical high performance materials'. The seminar looked beyond the refractory metals and cemented carbides, which remain as its focus, to novel classes of materials, such as intermetallic compounds, with potential for high temperature applications. This volume 4 contains papers dealing with high performance P/M metals (ITER and fusion reactors, solid targets, materials microstructure, novel alloys, etc.), P/M hard materials ( production and characterization, tungsten carbides, titanium carbides, microstructural design, coatings composition and performance, etc.) and general topics. From 37 papers 24 correspond to INIS subject scope and they were indexed separately. (nevyjel)

Perspectives on High School Reform. NCREL Viewpoints, Volume 13

Science.gov (United States)

Learning Point Associates / North Central Regional Educational Laboratory (NCREL), 2005

2005-01-01

Viewpoints is a multimedia package containing two audio CDs and a brief, informative booklet. This volume of Viewpoints focuses on issues related to high school reform. This booklet offers background information explaining the issues surrounding high school reform with perspectives from research, policy, and practice. It also provides a list of…

High-Temperature-High-Volume Lifting for Enhanced Geothermal Systems

Energy Technology Data Exchange (ETDEWEB)

Turnquist, Norman [GE Global Research, Munchen (Germany); Qi, Xuele [GE Global Research, Munchen (Germany); Raminosoa, Tsarafidy [GE Global Research, Munchen (Germany); Salas, Ken [GE Global Research, Munchen (Germany); Samudrala, Omprakash [GE Global Research, Munchen (Germany); Shah, Manoj [GE Global Research, Munchen (Germany); Van Dam, Jeremy [GE Global Research, Munchen (Germany); Yin, Weijun [GE Global Research, Munchen (Germany); Zia, Jalal [GE Global Research, Munchen (Germany)

2013-12-20

This report summarizes the progress made during the April 01, 2010 – December 30, 2013 period under Cooperative Agreement DE-EE0002752 for the U.S. Department of Energy entitled “High-Temperature-High-Volume Lifting for Enhanced Geothermal Systems.” The overall objective of this program is to advance the technology for well fluids lifting systems to meet the foreseeable pressure, temperature, and longevity needs of the Enhanced Geothermal Systems (EGS) industry for the coming ten years. In this program, lifting system requirements for EGS wells were established via consultation with industry experts and site visits. A number of artificial lift technologies were evaluated with regard to their applicability to EGS applications; it was determined that a system based on electric submersible pump (ESP) technology was best suited to EGS. Technical barriers were identified and a component-level technology development program was undertaken to address each barrier, with the most challenging being the development of a power-dense, small diameter motor that can operate reliably in a 300°C environment for up to three years. Some of the targeted individual component technologies include permanent magnet motor construction, high-temperature insulation, dielectrics, bearings, seals, thrust washers, and pump impellers/diffusers. Advances were also made in thermal management of electric motors. In addition to the overall system design for a full-scale EGS application, a subscale prototype was designed and fabricated. Like the full-scale design, the subscale prototype features a novel “flow-through-the-bore” permanent magnet electric motor that combines the use of high temperature materials with an internal cooling scheme that limits peak internal temperatures to <330°C. While the full-scale high-volume multi-stage pump is designed to lift up to 80 kg/s of process water, the subscale prototype is based on a production design that can pump 20 kg/s and has been modified

Transhiatal esophagectomy in a high volume institution

Directory of Open Access Journals (Sweden)

Strauss Dirk C

2008-08-01

Full Text Available Abstract Background The optimal operative approach for carcinoma at the lower esophagus and esophagogastric junction remains controversial. The aim of this study was to assess a single unit experience of transhiatal esophagectomy in an era when the use of systemic oncological therapies has increased dramatically. Study Design Between January 2000 and November 2006, 215 consecutive patients (182 males, 33 females, median age = 65 years underwent transhiatal esophagectomy; invasive malignancy was detected preoperatively in 188 patients. 90 patients (42% received neoadjuvant chemotherapy. Prospective data was obtained for these patients and cross-referenced with cancer registry survival data. Results There were 2 in-hospital deaths (0.9%. Major complications included: respiratory complications in 65 patients (30%, cardiovascular complications in 31 patients (14% and clinically apparent anastomotic leak in 12 patients (6%. Median length of hospital stay was 14 days. The radicality of resection was inversely related to T stage: an R0 resection was achieved in 98–100% of T0/1 tumors and only 14% of T4 tumors. With a median follow up of 26 months, one and five year survival rates were estimated at 81% and 48% respectively. Conclusion Transhiatal esophagectomy is an effective operative approach for tumors of the infracarinal esophagus and the esophagogastric junction. It is associated with low mortality and morbidity and a five survival rate of nearly 50% when combined with neoadjuvant chemotherapy.

Moderator's view: High-volume plasma exchange: pro, con and consensus.

Science.gov (United States)

Kaplan, Andre A

2017-09-01

I have been asked to comment on the pro and con opinions regarding high-volume plasma exchange. The authors of both positions have provided cogent arguments and a reasonable approach to choosing the exchange volume for any given therapeutic plasma exchange. The major issue of relevance in this discussion is the nature of the toxins targeted for removal. These parameters include molecular weight, the apparent volume of distribution, the degree of protein binding, the biologic and chemical half-life, and the severity and rapidity of its toxicity. © The Author 2017. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.

Effect of operator and institutional volume on clinical outcomes after percutaneous coronary interventions performed in Canada and the United States: a brief report from the Enhanced Suppression of the Platelet glycoprotein IIb/IIIa Receptor with Integrilin Therapy (ESPRIT) study.

Science.gov (United States)

Madan, Mina; Nikhil, Janarthan; Hellkamp, Anne S; Pieper, Karen S; Labinaz, Marino; Cohen, E A; Buller, Christopher E; Cantor, Warren J; Seidelin, Peter; Ducas, John; Carere, Ronald G; Natarajan, Madhu K; O'Shea, J Conor; Tcheng, James E

2009-08-01

The Enhanced Suppression of the Platelet glycoprotein IIb/IIIa Receptor with Integrilin Therapy (ESPRIT) trial compared the use of eptifibatide with placebo in 2064 coronary intervention patients. It was previously reported that Canadian patients had reduced rates of 30-day and one-year death, myocardial infarction (MI) or target vessel revascularization (TVR) compared with patients in the United States (US). To examine whether operator or institutional volume differences explain the regional variation in clinical outcome. Each site received an operator and institutional volume survey. Fifty-seven sites (62%) returned complete data on 1338 patients. In this smaller cohort, Canadian patients had reduced rates of 30-day and one-year death, MI or TVR compared with US patients (6.3% versus 10.3% and 14.9% versus 20.1%, respectively; PESPRIT study, institutional volume was associated with a modest reduction in risk of death, MI or TVR over short- and long-term follow-up periods. The Canadian and US investigators and institutions selected in ESPRIT had similar annual procedural volumes. Therefore, volume variables did not explain the differential risk of clinical events observed for patients enrolled in the two countries.

Case mix-adjusted cost of colectomy at low-, middle-, and high-volume academic centers.

Science.gov (United States)

Chang, Alex L; Kim, Young; Ertel, Audrey E; Hoehn, Richard S; Wima, Koffi; Abbott, Daniel E; Shah, Shimul A

2017-05-01

Efforts to regionalize surgery based on thresholds in procedure volume may have consequences on the cost of health care delivery. This study aims to delineate the relationship between hospital volume, case mix, and variability in the cost of operative intervention using colectomy as the model. All patients undergoing colectomy (n = 90,583) at 183 academic hospitals from 2009-2012 in The University HealthSystems Consortium Database were studied. Patient and procedure details were used to generate a case mix-adjusted predictive model of total direct costs. Observed to expected costs for each center were evaluated between centers based on overall procedure volume. Patient and procedure characteristics were significantly different between volume tertiles. Observed costs at high-volume centers were less than at middle- and low-volume centers. According to our predictive model, high-volume centers cared for a less expensive case mix than middle- and low-volume centers ($12,786 vs $13,236 and $14,497, P case mix at low-volume centers, which may lead to perceived poor performance at these centers. Copyright © 2016 Elsevier Inc. All rights reserved.

The effect of chronic erythrocytic polycythemia and high altitude upon plasma and blood volumes.

Science.gov (United States)

Burton, R. R.; Smith, A. H.

1972-01-01

Comparison of two kinds of physiological chronic erythrocytic polycythemias in order to differentiate the specific effect of erythrocytic polycythemia from the general effects of high altitude upon the plasma volume. The two kinds were produced hormonally in female chickens, at sea level, or by protracted high-altitude exposures. It appears that the vascular system of the body may account for an increase in red blood cell mass either by reduction in plasma volume, or by no change in plasma volume, resulting in differential changes in total blood volumes.

Presentation of the High-Flux Reactor of the Institut Laue-Langevin

International Nuclear Information System (INIS)

Guyon, H.

2006-01-01

Full text of publication follows: The High-Flux Reactor (HFR) of the Institut Laue-Langevin is the world's most intense source of neutrons for fundamental research. Thanks to its extremely compact core, which is made up of a single fuel element, the HFR is capable of producing a neutron flux of up to 1.5.10 15 n.cm -2 .s -1 with a moderate power output of 58 MW. Its heavy water reflector thermalizes these neutrons, giving them a wave length of the order of one angstrom. They then become an excellent tool for exploring the atomic structure of matter. In order to provide a full neutron spectrum, the reactor is also equipped with a hot source (a block of graphite heated to 2000 deg. C) and two cold sources (a volume of liquid deuterium at 25 K). All the reactor's components can be replaced and adapted in order to keep pace with both changing scientific needs and changing safety requirements. For example, in 1992 the reactor block was replaced, a second cold source was installed in 1985, and the beam tubes are replaced at regularly intervals and are also occasionally modified. In the same way, the reactor's civil engineering structures are currently being reinforced in order to comply with the reassessment of the reference earthquake spectra. Finally, the Institut Laue-Langevin's reactor is equipped with three solid containment barriers: - the fuel cladding: during the 35 years the reactor has been in operation, a cladding failure has never been detected; - the leak-tight primary cooling system: this is partly submerged in a pool which provides radiological shielding; - the double-wall containment: an overpressure of air is maintained between the inner reinforced concrete wall and the outer metal wall. The High-Flux Reactor is therefore all set to provide the scientific community with top quality service for the next 20 years to come, on a site which: - is home to the brightest synchrotron in the world (ESRF); - benefits from the microbiology expertise of the EMBL

Presentation of the High-Flux Reactor of the Institut Laue-Langevin

Energy Technology Data Exchange (ETDEWEB)

Guyon, H. [Institut Laue-Langevin, Grenoble (France)

2006-07-01

Full text of publication follows: The High-Flux Reactor (HFR) of the Institut Laue-Langevin is the world's most intense source of neutrons for fundamental research. Thanks to its extremely compact core, which is made up of a single fuel element, the HFR is capable of producing a neutron flux of up to 1.5.10{sup 15} n.cm{sup -2}.s{sup -1} with a moderate power output of 58 MW. Its heavy water reflector thermalizes these neutrons, giving them a wave length of the order of one angstrom. They then become an excellent tool for exploring the atomic structure of matter. In order to provide a full neutron spectrum, the reactor is also equipped with a hot source (a block of graphite heated to 2000 deg. C) and two cold sources (a volume of liquid deuterium at 25 K). All the reactor's components can be replaced and adapted in order to keep pace with both changing scientific needs and changing safety requirements. For example, in 1992 the reactor block was replaced, a second cold source was installed in 1985, and the beam tubes are replaced at regularly intervals and are also occasionally modified. In the same way, the reactor's civil engineering structures are currently being reinforced in order to comply with the reassessment of the reference earthquake spectra. Finally, the Institut Laue-Langevin's reactor is equipped with three solid containment barriers: - the fuel cladding: during the 35 years the reactor has been in operation, a cladding failure has never been detected; - the leak-tight primary cooling system: this is partly submerged in a pool which provides radiological shielding; - the double-wall containment: an overpressure of air is maintained between the inner reinforced concrete wall and the outer metal wall. The High-Flux Reactor is therefore all set to provide the scientific community with top quality service for the next 20 years to come, on a site which: - is home to the brightest synchrotron in the world (ESRF); - benefits from the

High energy physicists and graduate students. 1978 census

Energy Technology Data Exchange (ETDEWEB)

None

1978-11-01

This listing of physicists and students associated with the U.S. high-energy physics program was obtained by asking the research groups, laboratories, and other agencies involved to update previous information. The first part of this volume is an alphabetical listing and includes only the name, rank, and institution of high-energy physicists and graduate students. The second part of the volume is arranged by institution. Within each institution, the faculty (or permanent staff) and the graduate students are presented in separate alphabetical lists. For each person the entry indicates the year and institution of highest degree, rank and institutional affiliation with starting dates, up to three items selected from a list of research specialties, and sources of federal support. For the graduate students, there is also indicated an estimated date for their degree. Where appropriate, a person is listed at more than one institution. Except as noted in the headings, the information is intended to indicate the situation as of January 1, 1978. (RWR)

High energy physicists and graduate students. 1978 census

International Nuclear Information System (INIS)

1978-11-01

This listing of physicists and students associated with the U.S. high-energy physics program was obtained by asking the research groups, laboratories, and other agencies involved to update previous information. The first part of this volume is an alphabetical listing and includes only the name, rank, and institution of high-energy physicists and graduate students. The second part of the volume is arranged by institution. Within each institution, the faculty (or permanent staff) and the graduate students are presented in separate alphabetical lists. For each person the entry indicates birthdate, the year and institution of highest degree, rank and institutional affiliation with starting dates, up to three items selected from a list of research specialties, and sources of federal support. For the graduate students, there is also indicated an estimated date for their degree. Where appropriate, a person is listed at more than one institution. Except as noted in the headings, the information is intended to indicate the situation as of January 1, 1978

Salvage Treatment for Recurrent Intracranial Germinoma After Reduced-Volume Radiotherapy: A Single-Institution Experience and Review of the Literature

International Nuclear Information System (INIS)

Hu, Yu-Wen; Huang, Pin-I; Wong, Tai-Tong; Ho, Donald Ming-Tak; Chang, Kai-Ping; Guo, Wan-Yuo; Chang, Feng-Chi; Shiau, Cheng-Yin; Liang, Muh-Lii; Lee, Yi-Yen

2012-01-01

Purpose: Intracranial germinomas (IGs) are highly curable with radiotherapy (RT). However, recurrence still occurs, especially when limited-field RT is applied, and the optimal salvage therapy remains controversial. Methods and Materials: Between January 1989 and December 2010, 14 patients with clinically or pathologically diagnosed recurrent IGs after RT were reviewed at our institution. Of these, 11 received focal-field RT, and the other 3 received whole-brain irradiation, whole-ventricle irradiation, and Gamma Knife radiosurgery as the respective first course of RT. In addition, we identified from the literature 88 patients with recurrent IGs after reduced-volume RT, in whom the details of salvage therapy were recorded. Results: The median time to recurrence was 30.3 months (range, 3.8–134.9 months). One patient did not receive further treatment and was lost during follow-up. Of the patients, 7 underwent salvage with craniospinal irradiation (CSI) plus chemotherapy (CT), 4 with CSI alone, 1 with whole-brain irradiation plus CT, and 1 with Gamma Knife radiosurgery. The median follow-up time was 105.1 months (range, 24.2–180.9 months). Three patients died without evidence of disease progression: two from second malignancies and one from unknown cause. The others remained disease free. The 3-year survival rate after recurrence was 83.3%. A total of 102 patients from our study and the literature review were analyzed to determine the factors affecting prognosis and outcomes. After recurrence, the 5-year survival rates were 71% and 92.9% for all patients and for those receiving salvage CSI, respectively. Univariate analysis showed that initial RT volume, initial RT dose, initial CT, and salvage RT type were significant prognostic predictors of survival. On multivariable analysis, salvage CSI was the most significant factor (p = 0.03). Conclusions: Protracted follow-up is recommended because late recurrence is not uncommon. CSI with or without CT is an effective

Highly Insulating Windows Volume Purchase Program Final Report

Energy Technology Data Exchange (ETDEWEB)

None

2013-04-01

This report documents the development, execution outcomes and lessons learned of the Highly Insulating Windows Volume Purchase (WVP) Program carried out over a three-year period from 2009 through 2012. The primary goals of the program were met: 1) reduce the incremental cost of highly insulating windows compared to ENERGY STAR windows; and 2) raise the public and potential buyers’ awareness of highly insulating windows and their benefits. A key outcome of the program is that the 2013 ENERGY STAR Most Efficient criteria for primary residential windows were adopted from the technical specifications set forth in the WVP program.

High volume fly ash RCC for dams - I : mixture optimization and mechanical properties

Energy Technology Data Exchange (ETDEWEB)

Jacobsen, S. [PEAB Construction Co., Oslo (Norway); Lahus, O. [Norwegian Building Research Inst., Oslo (Norway)

2001-07-01

Roller compacted concretes (RCC) were developed for the Norwegian Skjerka hydropower project. RCCs were developed to have a high-volume fly ash content to address environmental issues, including the reduction of carbon dioxide emissions associated with dam construction. They also makes good use of waste product and conserve natural resources. This study examined a series of mixtures to determine the appropriateness of using RCC as a competing alternative to the traditional rock fill dam proposed for the Skjerka hydropower project. The main advantage of RCC is speed, allowing a relatively large dam to be constructed in just one summer season, saving financial costs and providing early return on the investment. In addition, fly ash can be used in the structure, using clean and renewable energy. Several procedures to proportion RCC mixtures were proposed, including the optimal paste volume method which is based on the assumption that an optimal RCC should have just enough paste to fill the space between particles when the granular skeleton has reached its maximum density under compaction. With this assumption, RCC tests began in 1998 in the laboratories of the Norwegian Building Research Institute. An ordinary portland cement was used and combined with ordinary low lime fly ash. Both coarse and fine aggregate were used. The tests determined the optimum paste-mortar ratio, the content of coarse aggregates and the production of specimens for test on hardened and fresh concrete. The study showed that the compressive strength of RCC increased with increasing cement/(cement + fly ash) ratio. The permeability coefficient decreased with increasing cement-content and increasing cement/(cement + fly ash) ratio due to the slow pozzolanic reaction of fly ash making a more open pore structure. It was concluded that an optimized mixture can result in a high performance RCC in terms of fresh and hardened concrete properties. 15 refs., 5 tabs., 11 figs.

Verification and validation guidelines for high integrity systems. Volume 1

Energy Technology Data Exchange (ETDEWEB)

Hecht, H.; Hecht, M.; Dinsmore, G.; Hecht, S.; Tang, D. [SoHaR, Inc., Beverly Hills, CA (United States)

1995-03-01

High integrity systems include all protective (safety and mitigation) systems for nuclear power plants, and also systems for which comparable reliability requirements exist in other fields, such as in the process industries, in air traffic control, and in patient monitoring and other medical systems. Verification aims at determining that each stage in the software development completely and correctly implements requirements that were established in a preceding phase, while validation determines that the overall performance of a computer system completely and correctly meets system requirements. Volume I of the report reviews existing classifications for high integrity systems and for the types of errors that may be encountered, and makes recommendations for verification and validation procedures, based on assumptions about the environment in which these procedures will be conducted. The final chapter of Volume I deals with a framework for standards in this field. Volume II contains appendices dealing with specific methodologies for system classification, for dependability evaluation, and for two software tools that can automate otherwise very labor intensive verification and validation activities.

Verification and validation guidelines for high integrity systems. Volume 1

International Nuclear Information System (INIS)

Hecht, H.; Hecht, M.; Dinsmore, G.; Hecht, S.; Tang, D.

1995-03-01

High integrity systems include all protective (safety and mitigation) systems for nuclear power plants, and also systems for which comparable reliability requirements exist in other fields, such as in the process industries, in air traffic control, and in patient monitoring and other medical systems. Verification aims at determining that each stage in the software development completely and correctly implements requirements that were established in a preceding phase, while validation determines that the overall performance of a computer system completely and correctly meets system requirements. Volume I of the report reviews existing classifications for high integrity systems and for the types of errors that may be encountered, and makes recommendations for verification and validation procedures, based on assumptions about the environment in which these procedures will be conducted. The final chapter of Volume I deals with a framework for standards in this field. Volume II contains appendices dealing with specific methodologies for system classification, for dependability evaluation, and for two software tools that can automate otherwise very labor intensive verification and validation activities

Self compacting concrete incorporating high-volumes of fly ash

Energy Technology Data Exchange (ETDEWEB)

Bouzoubaa, N. [Natural Resources Canada, Ottawa, ON (Canada). International Centre for Sustainable Development of Cement and Concrete; Lachemi, M. [Ryerson Polytechnic Univ., Toronto, ON (Canada). Dept. of Civil Engineering

2004-07-01

Self-compacting concrete (SCC) is now widely used in reinforced concrete structures. Fine materials such as fly ash ensure that the concrete has the necessary properties of high fluidity and cohesiveness. An experimental study was conducted in which 9 SCC mixtures and one control concrete were produced in order to evaluate SCC made with high-volumes of fly ash. The content of the cementitious materials remained constant at 400 kg/cubic metre, but the ratio of water to cementitious material ranged from 0.35 to 0.45. The viscosity and stability of the fresh concrete was determined for self-compacting mixtures of 40, 50 and 60 per cent Class F fly ash. The compressive strength and drying shrinkage were also determined for the hardened concretes. Results showed that the SCCs developed a 28-day compressive strength ranging from 26 to 48 MPa. It was concluded that high-volumes of Class F fly ash could offer the following advantages to an SCC: reduced construction time and labour cost; eliminate the need for vibration; reduce noise pollution; improve the filling capacity of highly congested structural members; and, ensure good structural performance. 19 refs., 8 tabs., 2 figs.

Is the Distance Worth It? Patients With Rectal Cancer Traveling to High-Volume Centers Experience Improved Outcomes.

Science.gov (United States)

Xu, Zhaomin; Becerra, Adan Z; Justiniano, Carla F; Boodry, Courtney I; Aquina, Christopher T; Swanger, Alex A; Temple, Larissa K; Fleming, Fergal J

2017-12-01

It is unclear whether traveling long distances to high-volume centers would compensate for travel burden among patients undergoing rectal cancer resection. The purpose of this study was to determine whether operative volume outweighs the advantages of being treated locally by comparing the outcomes of patients with rectal cancer treated at local, low-volume centers versus far, high-volume centers. This was a population-based study. The National Cancer Database was queried for patients with rectal cancer. Patients with stage II or III rectal cancer who underwent surgical resection between 2006 and 2012 were included. The outcomes of interest were margins, lymph node yield, receipt of neoadjuvant chemoradiation, adjuvant chemotherapy, readmission within 30 days, 30-day and 90-day mortality, and 5-year overall survival. A total of 18,605 patients met inclusion criteria; 2067 patients were in the long-distance/high-volume group and 1362 in the short-distance/low-volume group. The median travel distance was 62.6 miles for the long-distance/high-volume group and 2.3 miles for the short-distance/low-volume group. Patients who were younger, white, privately insured, and stage III were more likely to have traveled to a high-volume center. When controlled for patient factors, stage, and hospital factors, patients in the short-distance/low-volume group had lower odds of a lymph node yield ≥12 (OR = 0.51) and neoadjuvant chemoradiation (OR = 0.67) and higher 30-day (OR = 3.38) and 90-day mortality (OR = 2.07) compared with those in the long-distance/high-volume group. The short-distance/low-volume group had a 34% high risk of overall mortality at 5 years compared with the long-distance/high-volume group. We lacked data regarding patient and physician decision making and surgeon-specific factors. Our results indicate that when controlled for patient, tumor, and hospital factors, patients who traveled a long distance to a high-volume center had improved lymph node yield

High-pressure-assisted synthesis of high-volume ZnGeP2 polycrystalline

Science.gov (United States)

Huang, Changbao; Wu, Haixin; Xiao, Ruichun; Chen, Shijing; Ma, Jiaren

2018-06-01

The pnictide and chalcogenide semiconductors are promising materials for the applications in the field of photoelectric. High-purity and high-volume polycrystalline required in the real-world applications is hard to be synthesized due to the high vapor pressure of phosphorus and sulfur components at high temperature. A new high-pressure-resisted method was used to investigate the synthesis of the nonlinear-optical semiconductor ZnGeP2. The high-purity ZnGeP2 polycrystalline material of approximately 500 g was synthesized in one run, which enables the preparation of nominally stoichiometric material. Since increasing internal pressure resistance of quartz crucible and reducing the reaction space, the high-pressure-resisted method can be used to rapidly synthesize other pnictide and chalcogenide semiconductors and control the components ratio.

High tidal volume decreases adult respiratory distress syndrome, atelectasis, and ventilator days compared with low tidal volume in pediatric burned patients with inhalation injury.

Science.gov (United States)

Sousse, Linda E; Herndon, David N; Andersen, Clark R; Ali, Arham; Benjamin, Nicole C; Granchi, Thomas; Suman, Oscar E; Mlcak, Ronald P

2015-04-01

Inhalation injury, which is among the causes of acute lung injury and acute respiratory distress syndrome (ARDS), continues to represent a significant source of mortality in burned patients. Inhalation injury often requires mechanical ventilation, but the ideal tidal volume strategy is not clearly defined in burned pediatric patients. The aim of this study was to determine the effects of low and high tidal volume on the number of ventilator days, ventilation pressures, and incidence of atelectasis, pneumonia, and ARDS in pediatric burned patients with inhalation injury within 1 year post burn injury. From 1986 to 2014, inhalation injury was diagnosed by bronchoscopy in pediatric burned patients (n = 932). Patients were divided into 3 groups: unventilated (n = 241), high tidal volume (HTV, 15 ± 3 mL/kg, n = 190), and low tidal volume (LTV, 9 ± 3 mL/kg, n = 501). High tidal volume was associated with significantly decreased ventilator days (p tidal volume significantly decreases ventilator days and the incidence of both atelectasis and ARDS compared with low tidal volume in pediatric burned patients with inhalation injury. Therefore, the use of HTV may interrupt sequences leading to lung injury in our patient population. Copyright © 2015 American College of Surgeons. Published by Elsevier Inc. All rights reserved.

Durability properties of high volume fly ash self compacting concretes

Energy Technology Data Exchange (ETDEWEB)

P. Dinakar; K.G. Babu; Manu Santhanam [Indian Institute of Technology, Chennai (India). Building Technology Division

2008-11-15

This paper presents an experimental study on the durability properties of self compacting concretes (SCCs) with high volume replacements of fly ash. Eight fly ash self compacting concretes of various strength grades were designed at desired fly ash percentages of 0, 10, 30, 50, 70 and 85%, in comparison with five different mixtures of normal vibrated concretes (NCs) at equivalent strength grades. The durability properties were studied through the measurement of permeable voids, water absorption, acid attack and chloride permeation. The results indicated that the SCCs showed higher permeable voids and water absorption than the vibrated normal concretes of the same strength grades. However, in acid attack and chloride diffusion studies the high volume fly ash SCCs had significantly lower weight losses and chloride ion diffusion.

Commonplace Intersections within a High School Mathematics Leadership Institute

Science.gov (United States)

Sack, Jacqueline J.

2008-01-01

This narrative inquiry weaves Schwab's commonplaces of curriculum and Clandinin, Pushor, and Murray Orr's narrative commonplaces through stories of conflict between a professional developer and 30 high school lead teachers. In her role as manager of a mathematics leadership institute situated between two urban public school districts and a…

High energy physicists and graduate students: 1981 census

International Nuclear Information System (INIS)

1982-02-01

This listing of physicists and students associated with the US high energy physics program has been compiled in the Division of High Energy Physics of the Office of Energy Research of the US Department of Energy. This listing has been obtained by asking the research groups, laboratories, and other agencies involved to update previous information. This volume is in two parts. The first part is an alphabetical listing and includes only the name, rank, and institution of high energy physicists and graduate students. The second part of the volume is arranged by institution. Within each institution, the faculty (or permanent staff) and the graduate students are presented in separate alphabetical lists. For each person the entry indicates their birthdate, the year and institution of their highest degree, their rank and institutional affiliation with starting dates, up to three items selected from a list of research specialties, and their sources of federal support. For the graduate students, there is also indicated an estimated date for their degree. Where appropriate, a person is listed at more than one institution. Except as noted in the headings, the information is intended to indicate the situation as of January 1, 1981

Volume measurement variability in three-dimensional high-frequency ultrasound images of murine liver metastases

International Nuclear Information System (INIS)

Wirtzfeld, L A; Graham, K C; Groom, A C; MacDonald, I C; Chambers, A F; Fenster, A; Lacefield, J C

2006-01-01

The identification and quantification of tumour volume measurement variability is imperative for proper study design of longitudinal non-invasive imaging of pre-clinical mouse models of cancer. Measurement variability will dictate the minimum detectable volume change, which in turn influences the scheduling of imaging sessions and the interpretation of observed changes in tumour volume. In this paper, variability is quantified for tumour volume measurements from 3D high-frequency ultrasound images of murine liver metastases. Experimental B16F1 liver metastases were analysed in different size ranges including less than 1 mm 3 , 1-4 mm 3 , 4-8 mm 3 and 8-70 mm 3 . The intra- and inter-observer repeatability was high over a large range of tumour volumes, but the coefficients of variation (COV) varied over the volume ranges. The minimum and maximum intra-observer COV were 4% and 14% for the 1-4 mm 3 and 3 tumours, respectively. For tumour volumes measured by segmenting parallel planes, the maximum inter-slice distance that maintained acceptable measurement variability increased from 100 to 600 μm as tumour volume increased. Comparison of free breathing versus ventilated animals demonstrated that respiratory motion did not significantly change the measured volume. These results enable design of more efficient imaging studies by using the measured variability to estimate the time required to observe a significant change in tumour volume

Paul Scherrer Institut Annual Report 1998: General Volume

International Nuclear Information System (INIS)

Salzmann, M.

1999-01-01

This annual report presents an overview of the work performed by the PSI research departments including information on new developments connected with the various accelerators and on the status of the Swiss Light Source project (SLS). Details on the organizational and financial structure of the Institute are also provided

The study of multi-institutional collaborations in high-energy physics

International Nuclear Information System (INIS)

1991-01-01

Since World War II, the organizational framework for scientific research is increasingly the multi-institutional collaboration, especially in high-energy physics. A broad preliminary survey, into the functioning of research collaborations involving three or more institutions is described. The study is designed to identify patterns of collaborations, define the scope of the documentation problems, field-test possible solutions, recommend future actions, and build an archives of oral history interviews and other resources for scholarly use. Once the study is completed, its findings will be used to promote systems to document significant collaborative research

The study of multi-institutional collaborations in high-energy physics

Energy Technology Data Exchange (ETDEWEB)

Warnow-Blewett, Joan

1991-01-01

Since World War II, the organizational framework for scientific research is increasingly the multi-institutional collaboration, especially in high-energy physics. A broad preliminary survey, into the functioning of research collaborations involving three or more institutions is described. The study is designed to identify patterns of collaborations, define the scope of the documentation problems, field-test possible solutions, recommend future actions, and build an archives of oral history interviews and other resources for scholarly use. Once the study is completed, its findings will be used to promote systems to document significant collaborative research.

Comparison of the outcomes for laparoscopic gastrectomy performed by the same surgeon between a low-volume hospital and a high-volume center.

Science.gov (United States)

Kim, Min Gyu; Kwon, Sung Joon

2014-05-01

The volume-outcome relationship in laparoscopic surgery is controversial. This study was designed to identify differences in laparoscopic gastrectomy outcomes between a low-volume hospital and a high-volume center and to provide guidelines for overcoming the problems associated with a low-volume hospital. From April 2009 to November 2012, one surgeon performed 134 totally laparoscopic distal gastrectomies (TLDGs) at a high-volume center (HVC; ASAN Medical Center) and at a low-volume hospital (LVH; Hanyang University Guri Hospital). All laparoscopically assisted gastrectomies were excluded from this study. During the early period of laparoscopic gastrectomy at the low-volume hospital, TLDG with Roux-en-Y gastrojejunostomy (RYGJ) was performed according to the surgeon's choice. The reconstruction method was classified as gastroduodenostomy (GD) or RYGJ. Early surgical outcomes achieved at the LVH were investigated and compared with those obtained at the HVC. The early surgical outcomes differed significantly between the two hospitals. In particular, the postoperative complication rate for the patients who underwent TLDG RYGJ at the LVH was higher than at the HVC (LVH 15.4 % vs. HVC 0 %; p = 0.037). Furthermore, significant differences were observed in the mean operation time (TLDG GD: LVH 141.0 min vs. HVC 117.4 min, p = 0.001; TLDG RYGJ: LVH 186.3 min vs. HVC 134.6 min, p = 0.009) and length of hospital stay (TLDG GD: LVH 8.1 days vs. HVC 7.2 days, p = 0.044; TLDG RYGJ: LVH 11.5 day vs. HVC 6.8 day, p = 0.009). Although all the operations were performed by one experienced surgeon, the early surgical outcomes differed significantly between the low- and high-volume hospitals. Low-volume hospitals often lack well-trained surgical professionals such as first assistants and scrub nurses. Therefore, the authors recommend that a surgeon who works at an LVH should assess potential personnel shortages and find a solution before operating.

The NATO Advanced Study Institute on New Vistas in Electro-Nuclear Physics

CERN Document Server

Caplan, H S; Dressler, E T; The NATO Advanced Study Institute on New Vistas in Electro-Nuclear Physics

1986-01-01

The NATO Advanced Study Institute "New Vistas in Electro-Nuclear Physics" was held in Banff, Alberta, Canada from August 22 to September 4, 1985. This volume con­ tains the lecture notes from that Institute. The idea to organize this Institute coincided with the award of funding for a pulse stretcher ring at the University of Saskatchewan's Linear Accelerator Laboratory. This together with the high level of interest in electron accelerators worldwide convinced us that it was an appropriate time to discuss the physics to be learned with such machines. In particular that physics which requires high energy and/or high duty cycle accelerators for its extraction was intended to be the focus of the Institute. Thus the scope of the lec­ tures was wide, with topics ranging from the structure of the trinucleons to quark models of nucleons, QCD, and QHD. The theme however was that we are just trying to under­ stand the nucleus and that the electromagnetic probe can serve as a powerful tool in such a quest.

Applications of NAA at Institute of High Energy Physics

International Nuclear Information System (INIS)

Zhang Zhiyong; Chai Zhifang

2003-01-01

Recent achievements in application studies of neutron activation analysis (NAA) at Institute of High Energy Physics, The Chinese Academy of Sciences are briefly described. A small number of selected areas and problems, particularly in life sciences, are highlighted because they present challenges for NAA and its prospects in the future. (author)

Applications of NAA at Institute of High Energy Physics

Energy Technology Data Exchange (ETDEWEB)

Zhiyong, Zhang; Zhifang, Chai [Chinese Academy of Sciences, Institute of High Energy Physics, Beijing (China)

2003-03-01

Recent achievements in application studies of neutron activation analysis (NAA) at Institute of High Energy Physics, The Chinese Academy of Sciences are briefly described. A small number of selected areas and problems, particularly in life sciences, are highlighted because they present challenges for NAA and its prospects in the future. (author)

Excess Molar Volumes of the Heptane ů 1-Chloropentane System at High Pressures and Elevated Temperatures

Czech Academy of Sciences Publication Activity Database

Linek, Jan; Morávková, Lenka

2001-01-01

Roč. 55, č. 6 (2001), s. 382-385 ISSN 0366-6352. [28th International Conference of SSCHE. Tatranské Matliare, 21.05.2001-25.05.2001] R&D Projects: GA ČR GA203/00/0600 Institutional research plan: CEZ:AV0Z4072921 Keywords : measurement * excess molar volumes * apparatus Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 0.349, year: 2001

Nuclear physics and High Energy Physics Institute: 1988 to 1989 progress report

International Nuclear Information System (INIS)

1990-01-01

The 1988 to 1989 progress report of the Nuclear Physics and High Energy Physics National Institute (France) is presented. The main objectives of the Institute research programs are the identification of the fundamental components of matter, the study of the properties and interactions between quarks and leptons. The results and the experiments presented are: Z O event at LEP, hadron spectroscopy, CP violation, standard model, sixth quark, heavy ions at CERN, thermistocle experiment, high spin, exotic nuclei. The research and developments concerning instruments are also reported [fr

Impact of institutional volume and experience with CT interpretation on sizing of transcatheter aortic valves: A multicenter retrospective study

Energy Technology Data Exchange (ETDEWEB)

Verma, Divya Ratan [Cardiovascular Institute, Banner University Medical Center, Phoenix, AZ (United States); Division of Interventional Cardiology, Banner University Medical Center, Phoenix, AZ (United States); Pershad, Yash [Department of Radiology, Banner University Medical Center, Phoenix, AZ (United States); Pershad, Ashish [Cardiovascular Institute, Banner University Medical Center, Phoenix, AZ (United States); Division of Interventional Cardiology, Banner University Medical Center, Phoenix, AZ (United States); Fang, Kenith [Cardiovascular Institute, Banner University Medical Center, Phoenix, AZ (United States); Division of Cardiothoracic Surgery, Banner University Medical Center, Phoenix, AZ (United States); Gellert, George [Cardiovascular Institute, Banner University Medical Center, Phoenix, AZ (United States); Department of Anesthesiology, Banner University Medical Center, Phoenix, AZ (United States); Morris, Michael F., E-mail: mfmorris@mail.arizona.edu [Cardiovascular Institute, Banner University Medical Center, Phoenix, AZ (United States); Department of Radiology, Banner University Medical Center, Phoenix, AZ (United States)

2016-12-15

Background: Computed tomography (CT) has become the standard imaging modality for pre-procedural aortic annular sizing prior to transcatheter aortic valve replacement (TAVR). We hypothesized that the accuracy of CT derived annular measurements would be greater at sites with higher TAVR procedural volume. Methods: Within a large integrated health system, TAVR was performed at low (<40 cases), intermediate (40–75 cases), and high-volume sites (>75 cases). 181 patients underwent TAVR with a Sapien XT transcatheter heart valve (THV). Two blinded experienced readers independently remeasured the annulus on CT and compared their measurements to site reported measurements. Hypothetical THV sizes were chosen based on measurements from site CT reports and independent readers’ measurements, and compared to the implanted THV size. Results: Correlation between site reported measurements and independent readers measurements of mean annulus size varied between low-volume (r = 0.31, p = 0.18), intermediate-volume (r = 0.34, p = 0.01), and high-volume sites (r = 0.96, p < 0.01). On multivariate analysis, interpretation of ≥20 CT scans (OR 0.29; 95% CI 0.03–0.81; p 0.02) and high-volume site (OR 0.16; 95% CI 0.10–0.82; p 0.02) were associated with reduced mismatch between the site predicted THV size and independent readers predicted THV size. Mismatch between site predicted THV size and implanted THV size was associated with a worse 30-day composite of mortality, dialysis-dependent renal failure, cerebrovascular accident, new permanent pacemaker, and hospital readmission (55.3 vs. 38.7%; p = 0.05). Conclusions: Accuracy of CT aortic annular sizing is improved with higher individual experience and site TAVR volume. These findings should be confirmed in larger, prospective studies. - Highlights: • Accuracy of CT aortic annular sizing is improved with higher individual experience and site TAVR volume. • CT readers with experience interpreting ≥20 pre-TAVR CT scans had

Volume and outcome of organ transplantation

NARCIS (Netherlands)

Banta, H.D.; Engel, G.L.; Schersten, T.

1992-01-01

In general, technically demanding medical procedures are associated with better outcomes when they are carried out in institutions and by physicians with higher volumes of practice. This paper examines the evidence for a volume-outcome relationship in the case of organ transplantation. Although few

Service expectations from high- and low-volume customers in the alcoholic beverage industry

Directory of Open Access Journals (Sweden)

Jacques Beukes

2013-08-01

Research purpose: This research study investigated the relationship between the volume a customer buys from an alcoholic beverage supply company and what influence this volume has on their customer service expectations. Motivation for the study: The main purpose of this study was to evaluate what influence the volume an organisation buys from alcoholic beverage suppliers has on their service quality expectations. Research design, approach and method: A non-probability judgement sample method was used, with a sample size of 220 respondents. The questionnaire requested respondents (high- and low-volume to rank their customer service expectations and opinions with reference to Parasuraman’s service delivery dimensions. Ranking was done using a five-point Likert scale. Main findings: The findings of the study indicated that both the high- and low-volume customers felt that alcoholic beverage supply companies had to deliver on all five service delivery dimensions but failed to do so to full satisfaction. Practical and managerial implications: It is recommended that the alcoholic beverage supply companies should address the problem areas identified in this study to avoid defection of customers. Contribution and value add: This may assist alcoholic beverage supply companies to better understand the customers’ demographic profiles. The study also revealed that the satisfaction level experienced by customers in both sections of the study (high- and low-demand, with a considerable gap between expectations and opinions within the empathy dimension.

Editorial Volume 9, Issue 2 2018

Directory of Open Access Journals (Sweden)

Karen Nelson

2018-03-01

Full Text Available Welcome to our second issue for 2018.  In February we opened the year with the publication of Volume 9(1, a special issue dedicated to the top papers from the 6th Biennial National Association of Enabling Educators of Australia (NAEEA Conference which was hosted by Southern Cross University at the Gold Coast, Australia in December 2017.   Shortly after this Conference, the Australian Government announced that undergraduate funding was to be capped at 2017 levels, effectively stopping the demand driven funding system for high education in Australia.  With that backdrop Volume 9(1 was a timely opportunity to consider the impact of disruption, and as perceptions of the value of higher education are challenged, to reiterate the value of supporting access and equity to higher education institutions.

Responses to Hugh Heclo's "On Thinking Institutionally"

Science.gov (United States)

Fennell, Robert C.; Ascough, Richard S.; Liew, Tat-siong Benny; McLain, Michael; Westfield, Nancy Lynne

2010-01-01

Hugh Heclo's recent book "On Thinking Institutionally" (Paradigm Publishers, 2008) analyzes changes that have taken place in the past half century in how North Americans tend to think and act in institutions. The volume is receiving particular attention as it can be applied to higher education and to religious denominations, and so deserves…

Perioperative mortality in cats and dogs undergoing spay or castration at a high-volume clinic.

Science.gov (United States)

Levy, J K; Bard, K M; Tucker, S J; Diskant, P D; Dingman, P A

2017-06-01

High volume spay-neuter (spay-castration) clinics have been established to improve population control of cats and dogs to reduce the number of animals admitted to and euthanazed in animal shelters. The rise in the number of spay-neuter clinics in the USA has been accompanied by concern about the quality of animal care provided in high volume facilities, which focus on minimally invasive, time saving techniques, high throughput and simultaneous management of multiple animals under various stages of anesthesia. The aim of this study was to determine perioperative mortality for cats and dogs in a high volume spay-neuter clinic in the USA. Electronic medical records and a written mortality log were used to collect data for 71,557 cats and 42,349 dogs undergoing spay-neuter surgery from 2010 to 2016 at a single high volume clinic in Florida. Perioperative mortality was defined as deaths occurring in the 24h period starting with the administration of the first sedation or anesthetic drugs. Perioperative mortality was reported for 34 cats and four dogs for an overall mortality of 3.3 animals/10,000 surgeries (0.03%). The risk of mortality was more than twice as high for females (0.05%) as for males (0.02%) (P=0.008) and five times as high for cats (0.05%) as for dogs (0.009%) (P=0.0007). High volume spay-neuter surgery was associated with a lower mortality rate than that previously reported in low volume clinics, approaching that achieved in human surgery. This is likely to be due to the young, healthy population of dogs and cats, and the continuous refinement of techniques based on experience and the skills and proficiency of teams that specialize in a limited spectrum of procedures. Copyright © 2017 Elsevier Ltd. All rights reserved.

Low-load high volume resistance exercise stimulates muscle protein synthesis more than high-load low volume resistance exercise in young men.

Directory of Open Access Journals (Sweden)

Nicholas A Burd

Full Text Available BACKGROUND: We aimed to determine the effect of resistance exercise intensity (%1 repetition maximum-1RM and volume on muscle protein synthesis, anabolic signaling, and myogenic gene expression. METHODOLOGY/PRINCIPAL FINDINGS: Fifteen men (21+/-1 years; BMI=24.1+/-0.8 kg/m2 performed 4 sets of unilateral leg extension exercise at different exercise loads and/or volumes: 90% of repetition maximum (1RM until volitional failure (90FAIL, 30% 1RM work-matched to 90%FAIL (30WM, or 30% 1RM performed until volitional failure (30FAIL. Infusion of [ring-13C6] phenylalanine with biopsies was used to measure rates of mixed (MIX, myofibrillar (MYO, and sarcoplasmic (SARC protein synthesis at rest, and 4 h and 24 h after exercise. Exercise at 30WM induced a significant increase above rest in MIX (121% and MYO (87% protein synthesis at 4 h post-exercise and but at 24 h in the MIX only. The increase in the rate of protein synthesis in MIX and MYO at 4 h post-exercise with 90FAIL and 30FAIL was greater than 30WM, with no difference between these conditions; however, MYO remained elevated (199% above rest at 24 h only in 30FAIL. There was a significant increase in AktSer473 at 24h in all conditions (P=0.023 and mTORSer2448 phosphorylation at 4 h post-exercise (P=0.025. Phosporylation of Erk1/2Tyr202/204, p70S6KThr389, and 4E-BP1Thr37/46 increased significantly (P<0.05 only in the 30FAIL condition at 4 h post-exercise, whereas, 4E-BP1Thr37/46 phosphorylation was greater 24 h after exercise than at rest in both 90FAIL (237% and 30FAIL (312% conditions. Pax7 mRNA expression increased at 24 h post-exercise (P=0.02 regardless of condition. The mRNA expression of MyoD and myogenin were consistently elevated in the 30FAIL condition. CONCLUSIONS/SIGNIFICANCE: These results suggest that low-load high volume resistance exercise is more effective in inducing acute muscle anabolism than high-load low volume or work matched resistance exercise modes.

Homi Bhabha Centre for Science Education, Tata Institute of ...

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 22; Issue 2. Homi Bhabha Centre for Science Education, Tata Institute of Fundamental Research (A Deemed University). Information and Announcements Volume 22 Issue 2 February 2017 pp 189-189 ...

US evaluation of volume brain lesions produced by high-intensity focused US

International Nuclear Information System (INIS)

Chua, R.V.; Chua, G.T.; Fry, F.J.; Franklin, T.D.; Wills, E.R.; Hastings, J.S.; Sanghui, N.T.

1987-01-01

Eighteen volume brain lesions produced by high-intensity focused US in the right cerebral hemispheres of research canines were evaluated by diagnostic US from immediately after ablation up to 62 days later. Animals were killed and perfused for whole-brain recovery. US evaluation of whole-brain specimens was performed. Histologic analysis of brain sections verified lesion placement, size, and tissue response to US. These sections were compared with US studies for correlation data. Correlation data suggest that US visualization may aid in accurate placement of volume brain lesions and in evaluation of effects of high-intensity focuses US in normal brain

Paul Scherrer Institut Annual Report 1998: General Volume

Energy Technology Data Exchange (ETDEWEB)

Salzmann, M [ed.

1999-09-01

This annual report presents an overview of the work performed by the PSI research departments including information on new developments connected with the various accelerators and on the status of the Swiss Light Source project (SLS). Details on the organizational and financial structure of the Institute are also provided This annual report is also available in German under the title `PSI Jahresbericht 1998; Allgemeiner Teil`.figs.

Secure data storage by three-dimensional absorbers in highly scattering volume medium

International Nuclear Information System (INIS)

Matoba, Osamu; Matsuki, Shinichiro; Nitta, Kouichi

2008-01-01

A novel data storage in a volume medium with highly scattering coefficient is proposed for data security application. Three-dimensional absorbers are used as data. These absorbers can not be measured by interferometer when the scattering in a volume medium is strong enough. We present a method to reconstruct three-dimensional absorbers and present numerical results to show the effectiveness of the proposed data storage.

Functionality and Performance Visualization of the Distributed High Quality Volume Renderer (HVR)

KAUST Repository

Shaheen, Sara

2012-07-01

Volume rendering systems are designed to provide means to enable scientists and a variety of experts to interactively explore volume data through 3D views of the volume. However, volume rendering techniques are computationally intensive tasks. Moreover, parallel distributed volume rendering systems and multi-threading architectures were suggested as natural solutions to provide an acceptable volume rendering performance for very large volume data sizes, such as Electron Microscopy data (EM). This in turn adds another level of complexity when developing and manipulating volume rendering systems. Given that distributed parallel volume rendering systems are among the most complex systems to develop, trace and debug, it is obvious that traditional debugging tools do not provide enough support. As a consequence, there is a great demand to provide tools that are able to facilitate the manipulation of such systems. This can be achieved by utilizing the power of compute graphics in designing visual representations that reflect how the system works and that visualize the current performance state of the system.The work presented is categorized within the field of software Visualization, where Visualization is used to serve visualizing and understanding various software. In this thesis, a number of visual representations that reflect a number of functionality and performance aspects of the distributed HVR, a high quality volume renderer system that uses various techniques to visualize large volume sizes interactively. This work is provided to visualize different stages of the parallel volume rendering pipeline of HVR. This is along with means of performance analysis through a number of flexible and dynamic visualizations that reflect the current state of the system and enables manipulation of them at runtime. Those visualization are aimed to facilitate debugging, understanding and analyzing the distributed HVR.

Back-end interconnection. A generic concept for high volume manufacturing

Energy Technology Data Exchange (ETDEWEB)

Bosman, J.; Budel, T.; De Kok, C.J.G.M.

2013-10-15

The general method to realize series connection in thin film PV modules is monolithical interconnection through a sequence of laser scribes (P1, P2 and P3) and layer depositions. This method however implies that the deposition processes are interrupted several times, an undesirable situation in high volume processing. In order to eliminate this drawback we focus our developments on the so called 'back-end interconnection concept' in which series interconnection takes place AFTER the deposition of the functional layers of the thin film PV device. The process of making a back-end interconnection combines laser scribing, curing, sintering and inkjet processes. These different processes interacts with each other and are investigated in order to create processing strategies that are robust to ensure high volume production. The generic approach created a technology base that can be applied to any thin film PV technology.

100th anniversary of the birth of I Ya Pomeranchuk (Extended session of the all-institute seminar at the Alikhanov Institute for Theoretical and Experimental Physics, 5 - 6 June 2013)

Science.gov (United States)

2014-02-01

On 5 - 6 June 2013, an extended session of the all-institute seminar was held at the Russian Federation State Scientific Center 'Alikhanov Institute for Theoretical and Experimental Physics' (ITEP). It was devoted to the 100th anniversary of the birth of Academician Isaak Yakovlevich Pomeranchuk, the founder of the Theory Department of ITEP. The announced agenda of the session on the ITEP website http://www.itep.ru/rus/Pomeranchuk100.html contained the following reports: (1) Gershtein S S (SRC 'Institute for High Energy Physics', Protvino, Moscow region) "I Ya Pomeranchuk and the large accelerator";(2) Keldysh L V (Lebedev Physical Institute, RAS (FIAN), Moscow) "Dynamic tunneling";(3) Vaks V G (National Research Centre 'Kurchatov Institute' (NRC KI), Moscow) "Brief reminiscences";(4) Smilga A V (Laboratoire Physique Subatomique et des technologies associées, Université de Nantes, France) "Vacuum structure in 3D supersymmetric gauge theories";(5) Khriplovich I B (Budker Institute of Nuclear Physics, SB RAS, Novosibirsk) "Gravitational four-fermion interaction and early Universe dynamics";(6) Dremin I M (FIAN, Moscow) "Elastic scattering of hadrons";(7) Belavin A A (Landau Institute of Theoretical Physics, RAS, Moscow) "Correlators in minimal string models";(8) Voloshin M B (Theoretical Physics Institute, University of Minnesota, USA) "Exotic quarkonium";(9) Nekrasov N A (Institut des hautes études scientifiques (IHES), France) "BPS/CFT correspondence";(10) Zarembo K (Uppsala Universitet, Sweden) "Exact results in supersymmetric theories and AdS/CFT correspondence";(11) Gorsky A S (ITEP, Moscow) "Baryon as a dyon instanton";(12) Blinnikov S I (ITEP, Moscow) "Mirror substance and other models for dark matter";(13) Rubakov V A (Institute for Nuclear Research, RAS, Moscow) "Test-tube Universe";(14) Kancheli O V (ITEP, Moscow) "50 years of reggistics";(15) Shevchenko V I (NRC KI) "In search of the chiral magnetic effect";(16) Kirilin V P (ITEP, Moscow) "Anomalies and

Do high-volume hospitals and surgeons provide better care in urologic oncology?

Science.gov (United States)

Eastham, James A

2009-01-01

Studies focusing primarily on hospital or surgical volume as a surrogate for surgical experience have found substantial variations in outcomes. Increasing surgical experience has been shown to improve outcomes after multiple procedures, including esophagectomy, pancreatectomy, and primary surgery for colon and breast cancer. More recently, evidence has been presented that surgical volume/experience affects quality of life and cancer control outcomes after urologic oncology procedures. Although most of these data pertain to radical prostatectomy, similar conclusions have been reached for radical cystectomy, retroperitoneal lymph node dissection, and management of renal cell carcinoma. This review highlights data indicating that high-volume surgeons and hospitals provide better care for radical prostatectomy.

Low versus high volume of culture medium during embryo transfer: a randomized clinical trial.

Science.gov (United States)

Sigalos, George Α; Michalopoulos, Yannis; Kastoras, Athanasios G; Triantafyllidou, Olga; Vlahos, Nikos F

2018-04-01

The aim of this prospective randomized control trial was to evaluate if the use of two different volumes (20-25 vs 40-45 μl) of media used for embryo transfer affects the clinical outcomes in fresh in vitro fertilization (IVF) cycles. In total, 236 patients were randomized in two groups, i.e., "low volume" group (n = 118) transferring the embryos with 20-25 μl of medium and "high volume" group (n = 118) transferring the embryos with 40-45 μl of medium. The clinical pregnancy, implantation, and ongoing pregnancy rates were compared between the two groups. No statistically significant differences were observed in clinical pregnancy (46.8 vs 54.3%, p = 0.27), implantation (23.7 vs 27.8%, p = 0.30), and ongoing pregnancy (33.3 vs 40.0%, p = 0.31) rates between low and high volume group, respectively. Higher volume of culture medium to load the embryo into the catheter during embryo transfer does not influence the clinical outcome in fresh IVF cycles. NCT03350646.

Resistance to Corrosion of Reinforcement of High Volume Fly Ash Concrete

International Nuclear Information System (INIS)

Kwon, S. O.; Bae, S. H.; Lee, H. J.; Lee, K. M.; Jung, S. H.

2014-01-01

Due to the increasing of interest about the eco-friendly concrete, it is increased to use concretes containing by-products of industry such as fly ash(FA), ground granulated blast furnace slag(GGBFS), silica fume(SF), and etc. Especially, these are well known for improving the resistances to reinforcement corrosion in concrete and decreasing chloride ion penetration. The purpose of this experimental research is to evaluate the resistance against corrosion of reinforcement of high volume fly ash(HVFA) concrete which is replaced with high volume fly ash for cement volume. For this purpose, the concrete test specimens were made for various strength level and replacement ratio of FA, and then the compressive strength and diffusion coefficient for chloride ion of them were measured for 28, 91, and 182 days, respectively. Also, corrosion monitoring by half cell potential method was carried out for the made lollypop concrete test specimens to detect the time of corrosion initiation for reinforcement in concrete. As a result, it was observed from the test results that the compressive strength of HVFA concrete was decreased with increasing replacement ratio of FA but long-term resistances against reinforcement corrosion and chloride ion penetration of that were increased

Protein-bound toxins: added value in their removal with high convective volumes.

Science.gov (United States)

Abad, Soraya; Vega, Almudena; Quiroga, Borja; Arroyo, David; Panizo, Nayara; Reque, Javier Eduardo; López-Gómez, Juan Manuel

Chronic kidney disease is associated with an increased risk of cardiovascular events. In recent years, protein-bound toxins have become more important due to their association with increased morbidity and mortality, characterised by inadequate clearance during dialysis. The purpose of this study is to assess the influence of high convective volumes on postdilution online haemodiafiltration (OL-HDF) on the removal of medium-sized molecules, small molecules and protein-bound molecules. In forty postdilutional OL-HDF sessions, the reduction rates of toxins of different molecular weights were measured in 13 patients, including protein-bound molecules such as p-cresyl sulphate, indoxyl sulphate and homocysteine. Total convective volume was 28.3 (5.1) litres (range 16.3-38.0 litres). Mean reduction rate of protein-bound molecules was 44.4% (15.7%), 48.7% (14.1%) and 58.6% (8.8%) for p-cresyl sulphate, indoxyl sulphate and homocysteine, respectively. Moreover, a statistically significant direct association was found between the reduction rates of all three molecules, the replacement volume and the Kt/V. High convective volumes during postdilution OL-HDF are associated with increased removal of protein-bound uraemic toxins. Copyright © 2016 Sociedad Española de Nefrología. Published by Elsevier España, S.L.U. All rights reserved.

High-volume intensive training course: a new paradigm for video-assisted thoracoscopic surgery education.

Science.gov (United States)

Sihoe, Alan D L; Gonzalez-Rivas, Diego; Yang, Timothy Y; Zhu, Yuming; Jiang, Gening

2018-03-27

The emergence of ultra-high-volume centres promises new opportunities for thoracic surgical training. The goal of this study was to investigate the effectiveness of a novel observership course in teaching video-assisted thoracoscopic surgery (VATS) at an ultra-high-volume centre. Two-week courses in VATS at a specialist unit now performing >10 000 major lung resections annually (>50 daily on average) were attended by 230 surgeons from around the world from 2013 to 2016. An online survey preserving responder anonymity was completed by 156 attendees (67.8%). Attendees included 37% from Western Europe, 18% from Eastern Europe and 17% from Latin America. Experience with open thoracic surgery for more than 5 years was reported by 67%, but 79% had less than 5 years of VATS lobectomy experience. During the course, 70% observed over 30 uniportal VATS operations (including 38% observing over 50), and 69% attended an animal wet lab. Although 72% of the responders attended the course less than 12 months ago, the number of ports used (P < 0.001), operation times (P < 0.001) and conversion rates (P < 0.001) reported by the responders were reduced significantly after the course. Improvements in the problem areas of tissue retraction, instrumentation, stapler application and coordination with the assistant during VATS were reported by 56%, 57%, 58% and 53%, respectively. Of those who had attended other VATS courses previously, 87% preferred the training from this high-volume course. High-volume intensive observership training at an ultra-high-volume centre may improve VATS proficiency in a short period of time, and may provide a time-efficient modality for future thoracic surgical training.

Preferential effects of low volume versus high volume replacement with crystalloid fluid in a hemorrhagic shock model in pigs.

Science.gov (United States)

Ponschab, Martin; Schöchl, Herbert; Keibl, Claudia; Fischer, Henrik; Redl, Heinz; Schlimp, Christoph J

2015-10-06

Fluid resuscitation is a core stone of hemorrhagic shock therapy, and crystalloid fluids seem to be associated with lower mortality compared to colloids. However, as redistribution starts within minutes, it has been suggested to replace blood loss with a minimum of a three-fold amount of crystalloids. The hypothesis was that in comparison to high volume (HV), a lower crystalloid volume (LV) achieves a favorable coagulation profile and exerts sufficient haemodynamics in the acute phase of resuscitation. In 24 anaesthetized pigs, controlled arterial blood loss of 50 % of the estimated blood volume was either (n = 12) replaced with a LV (one-fold) or a HV (three-fold) volume of a balanced, acetated crystalloid solution at room temperature. Hemodynamic parameters, dilution effects and coagulation profile by standard coagulation tests and thromboelastometry at baseline and after resuscitation were determined in both groups. LV resuscitation increased MAP significantly less compared to the HV, 61 ± 7 vs. 82 ± 14 mmHg (p controlled blood loss, a one fold LV crystalloid replacement strategy is sufficient to adequately raise blood pressure up to a mean arterial pressure >50 mm Hg. The concept of damage control resuscitation (DCR) with permissive hypotension may be better met by using LV as compared to a three fold HV resuscitation strategy. High volume administration of an acetated balanced crystalloid does not lead to hyperchloraemic acidosis, but may negatively influence clinical parameters, such as higher blood pressure, lower body temperature and impaired coagulation parameters, which could potentially increase bleeding after trauma. Replacement of acute blood loss with just an equal amount of an acetated balanced crystalloid appears to be the preferential treatment strategy in the acute phase after controlled bleeding.

Impact of institutional volume and experience with CT interpretation on sizing of transcatheter aortic valves: A multicenter retrospective study

International Nuclear Information System (INIS)

Verma, Divya Ratan; Pershad, Yash; Pershad, Ashish; Fang, Kenith; Gellert, George; Morris, Michael F.

2016-01-01

Background: Computed tomography (CT) has become the standard imaging modality for pre-procedural aortic annular sizing prior to transcatheter aortic valve replacement (TAVR). We hypothesized that the accuracy of CT derived annular measurements would be greater at sites with higher TAVR procedural volume. Methods: Within a large integrated health system, TAVR was performed at low ( 75 cases). 181 patients underwent TAVR with a Sapien XT transcatheter heart valve (THV). Two blinded experienced readers independently remeasured the annulus on CT and compared their measurements to site reported measurements. Hypothetical THV sizes were chosen based on measurements from site CT reports and independent readers’ measurements, and compared to the implanted THV size. Results: Correlation between site reported measurements and independent readers measurements of mean annulus size varied between low-volume (r = 0.31, p = 0.18), intermediate-volume (r = 0.34, p = 0.01), and high-volume sites (r = 0.96, p < 0.01). On multivariate analysis, interpretation of ≥20 CT scans (OR 0.29; 95% CI 0.03–0.81; p 0.02) and high-volume site (OR 0.16; 95% CI 0.10–0.82; p 0.02) were associated with reduced mismatch between the site predicted THV size and independent readers predicted THV size. Mismatch between site predicted THV size and implanted THV size was associated with a worse 30-day composite of mortality, dialysis-dependent renal failure, cerebrovascular accident, new permanent pacemaker, and hospital readmission (55.3 vs. 38.7%; p = 0.05). Conclusions: Accuracy of CT aortic annular sizing is improved with higher individual experience and site TAVR volume. These findings should be confirmed in larger, prospective studies. - Highlights: • Accuracy of CT aortic annular sizing is improved with higher individual experience and site TAVR volume. • CT readers with experience interpreting ≥20 pre-TAVR CT scans had significantly improved accuracy in identifying the annulus. �

High Energy Performance Tests of Large Volume LaBr{sub 3}:Ce Detector

Energy Technology Data Exchange (ETDEWEB)

Naqvi, A.A.; Gondal, M.A.; Khiari, F.Z.; Dastageer, M.A. [Department of Physics, King Fahd University of Petroleum and Minerals, Dhahran (Saudi Arabia); Maslehuddin, M.M. [Center for Engineering Research, King Fahd University of Petroleum and Minerals, Dhahran (Saudi Arabia); Al-Amoudi, O.S.B. [Department of Civil Engineering, King Fahd University of Petroleum and Minerals, Dhahran (Saudi Arabia)

2015-07-01

High energy prompt gamma ray tests of a large volume cylindrical 100 mm x 100 mm (height x diameter) LaBr{sub 3}:Ce detector were carried out using a portable neutron generator-based Prompt Gamma Neutron Activation Analysis (PGNAA) setup. In this study prompt gamma-rays yield were measured from water samples contaminated with toxic elements such nickel, chromium and mercury compounds with gamma ray energies up to 10 MeV. The experimental yield of prompt gamma-rays from toxic elements were compared with the results of Monte Carlo calculations. In spite of its higher intrinsic background due to its larger volume, an excellent agreement between the experimental and calculated yields of high energy gamma-rays from Ni, Cr and Hg samples has been achieved for the large volume LaBr{sub 3}:Ce detector. (authors)

A reliable and consistent production technology for high volume compacted graphite iron castings

Directory of Open Access Journals (Sweden)

Liu Jincheng

2014-07-01

Full Text Available The demands for improved engine performance, fuel economy, durability, and lower emissions provide a continual challenge for engine designers. The use of Compacted Graphite Iron (CGI has been established for successful high volume series production in the passenger vehicle, commercial vehicle and industrial power sectors over the last decade. The increased demand for CGI engine components provides new opportunities for the cast iron foundry industry to establish efficient and robust CGI volume production processes, in China and globally. The production window range for stable CGI is narrow and constantly moving. Therefore, any one step single addition of magnesium alloy and the inoculant cannot ensure a reliable and consistent production process for complicated CGI engine castings. The present paper introduces the SinterCast thermal analysis process control system that provides for the consistent production of CGI with low nodularity and reduced porosity, without risking the formation of flake graphite. The technology is currently being used in high volume Chinese foundry production. The Chinese foundry industry can develop complicated high demand CGI engine castings with the proper process control technology.

Is an institute for the study of high-level radioactive waste disposal needed in southern Nevada?

International Nuclear Information System (INIS)

Blanchard, M.B.; Robison, A.C.; Baepler, D.H.

1993-01-01

This paper examines key questions about the need for a formal institute that would study storage and disposal concepts for high-level radioactive waste (HLRW) in the United States and throughout the world. The questions that have been analyzed so far include: Why is an institute needed? What could this institute do to achieve the goal? How could an institute of this nature work? When could an institute form and begin functioning to meet the goals? Where could an institute be located?

Reduction on high level radioactive waste volume and geological repository footprint with high burn-up and high thermal efficiency of HTGR

Energy Technology Data Exchange (ETDEWEB)

Fukaya, Yuji, E-mail: fukaya.yuji@jaea.go.jp; Nishihara, Tetsuo

2016-10-15

Highlights: • We evaluate the number of canisters and its footprint for HTGR. • We proposed new waste loading method for direct disposal of HTGR. • HTGR can significantly reduce HLW volume compared with LWR. - Abstract: Reduction on volume of High Level radioactive Waste (HLW) and footprint in a geological repository due to high burn-up and high thermal efficiency of High Temperature Gas-cooled Reactor (HTGR) has been investigated. A helium-cooled and graphite-moderated commercial HTGR was designed as a Gas Turbine High Temperature Reactor (GTHTR300), and that has particular features such as significantly high burn-up of approximately 120 GWd/t, high thermal efficiency around 50%, and pin-in-block type fuel. The pin-in-block type fuel was employed to reduce processed graphite volume in reprocessing. By applying the feature, effective waste loading method for direct disposal is proposed in this study. By taking into account these feature, the number of HLW canister generations and its repository footprint are evaluated by burn-up fuel composition, thermal calculation and criticality calculation in repository. As a result, it is found that the number of canisters and its repository footprint per electricity generation can be reduced by 60% compared with Light Water Reactor (LWR) representative case for direct disposal because of the higher burn-up, higher thermal efficiency, less TRU generation, and effective waste loading proposed in this study for HTGR. But, the reduced ratios change to 20% and 50% if the long term durability of LWR canister is guaranteed. For disposal with reprocessing, the number of canisters and its repository footprint per electricity generation can be reduced by 30% compared with LWR because of the 30% higher thermal efficiency of HTGR.

Trading volume and the number of trades : a comparative study using high frequency data

OpenAIRE

Izzeldin, Marwan

2007-01-01

Trading volume and the number of trades are both used as proxies for market activity, with disagreement as to which is the better proxy for market activity. This paper investigates this issue using high frequency data for Cisco and Intel in 1997. A number of econometric methods are used, including GARCH augmented with lagged trading volume and number of trades, tests based on moment restrictions, regression analysis of volatility on volume and trades, normality of returns when standardized by...

High-pitch dual-source CT coronary angiography with low volumes of contrast medium

International Nuclear Information System (INIS)

Lembcke, Alexander; Hein, Patrick A.; Knobloch, Gesine; Durmus, Tahir; Hamm, Bernd; Schwenke, Carsten; Huppertz, Alexander

2014-01-01

To assess the effect of lower volumes of contrast medium (CM) on image quality in high-pitch dual-source computed tomography coronary angiography (CTCA). One-hundred consecutive patients (body weight 65-85 kg, stable heart rate ≤65 bpm, cardiac index ≥2.5 L/min/m 2 ) referred for CTCA were prospectively enrolled. Patients were randomly assigned to one of five groups of different CM volumes (G 30 , 30 mL; G 40 , 40 mL; G 50 , 50 mL; G 60 , 60 mL; G 70 , 70 mL; flow rate 5 mL/s each, iodine content 370 mg/mL). Attenuation within the proximal and distal coronary artery segments was analysed. Mean attenuation for men and women ranged from 345.0 and 399.1 HU in G 30 to 478.2 and 571.8 HU in G 70 . Mean attenuation values were higher in groups with higher CM volumes (P 30 , G 40 , G 50 , G 60 and G 70 were 89 %, 95 %, 98 %, 98 % and 99 %. CM volume of 30 mL in women and 40 mL in men proved to be sufficient to guarantee attenuation of at least 300 HU. In selected patients high-pitch dual-source CTCA can be performed with CM volumes of 40 mL in men or 30 mL in women. (orig.)

The current status of emergency operations at a high-volume cancer center.

Science.gov (United States)

Komori, Koji; Kimura, Kenya; Kinoshita, Takashi; Ito, Seiji; Abe, Tetsuya; Senda, Yoshiki; Misawa, Kazunari; Ito, Yuichi; Uemura, Norihisa; Natsume, Seiji; Kawai, Ryosuke; Kawakami, Jiro; Asano, Tomonari; Iwata, Yoshinori; Kurahashi, Shintaro; Tsutsuyama, Masayuki; Shigeyoshi, Itaru; Shimizu, Yasuhiro

2014-01-01

This study aimed to assess the pathogenic causes, clinical conditions, surgical procedures, in-hospital mortality, and operative death associated with emergency operations at a high-volume cancer center. Although many reports have described the contents, operative procedures, and prognosis of elective surgeries in high-volume cancer centers, emergency operations have not been studied in sufficient detail. We retrospectively enrolled 28 consecutive patients who underwent emergency surgery. Cases involving operative complications were excluded. The following surgical procedures were performed during emergency operations: closure in 3 cases (10.7%), diversion in 22 cases (78.6%), ileus treatment in 2 cases (7.1%), and hemostasis in 1 case (3.6%). Closure alone was performed only once for peritonitis. Diversion was performed in 17 cases (77.3%) of peritonitis, 4 cases (18.2%) of stenosis of the gastrointestinal tract, and 1 case (4.5%) of bleeding. There was a significant overall difference (P = 0.001). The frequency of emergency operations was very low at a high-volume cancer center. However, the recent shift in treatment approaches toward nonoperative techniques may enhance the status of emergency surgical procedures. The results presented in this study will help prepare for emergency situations and resolve them as quickly and efficiently as possible.

Automated high speed volume computed tomography for inline quality control

International Nuclear Information System (INIS)

Hanke, R.; Kugel, A.; Troup, P.

2004-01-01

Increasing complexity of innovative products as well as growing requirements on quality and reliability call for more detailed knowledge about internal structures of manufactured components rather by 100 % inspection than just by sampling test. A first-step solution, like radioscopic inline inspection machines, equipped with automated data evaluation software, have become state of the art in the production floor during the last years. However, these machines provide just ordinary two-dimensional information and deliver no volume data e.g. to evaluate exact position or shape of detected defects. One way to solve this problem is the application of X-ray computed tomography (CT). Compared to the performance of the first generation medical scanners (scanning times of many hours), today, modern Volume CT machines for industrial applications need about 5 minutes for a full object scan depending on the object size. Of course, this is still too long to introduce this powerful method into the inline production quality control. In order to gain acceptance, the scanning time including subsequent data evaluation must be decreased significantly and adapted to the manufacturing cycle times. This presentation demonstrates the new technical set up, reconstruction results and the methods for high-speed volume data evaluation of a new fully automated high-speed CT scanner with cycle times below one minute for an object size of less than 15 cm. This will directly create new opportunities in design and construction of more complex objects. (author)

Analysis of the high water wave volume for the Sava River near Zagreb

Science.gov (United States)

Trninic, Dusan

2010-05-01

The paper analyses volumes of the Sava River high water waves near Zagreb during the period: 1926-2008 (N = 83 years), which is needed for more efficient control of high and flood waters. The primary Sava flood control structures in the City of Zagreb are dikes built on both riverbanks, and the Odra Relief Canal with lateral spillway upstream from the City of Zagreb. Intensive morphological changes in the greater Sava area near Zagreb, and anthropological and climate variations and changes at the Sava catchment up to the Zagreb area require detailed analysis of the water wave characteristics. In one analysis, maximum annual volumes are calculated for high water waves with constant duration of: 10, 20, 30, 40, 50 and 60 days. Such calculations encompass total quantity of water (basic and surface runoff). The log Pearson III distribution is adapted for this series of maximum annual volumes. Based on the results obtained, the interrelations are established between the wave volume as function of duration and occurrence probability. In addition to the analysis of maximum volumes of constant duration, it is interesting to carry out the analyses of maximum volume in excess of the reference discharge since it is very important for the flood control. To determine the reference discharges, a discharge of specific duration is used from an average discharge duration curve. The adopted reference discharges have durations of 50, 40, 30, 20 and 10%. Like in the previous case, log Pearson III distribution is adapted to the maximum wave data series. For reference discharge Q = 604 m3/s (duration 10%), a linear trend is calculated of maximum annual volumes exceeding the reference discharge for the Sava near Zagreb during the analyzed period. The analysis results show a significant decrease trend. A similar analysis is carried out for the following three reference discharges: regular flood control measures at the Sava near Zagreb, which are proclaimed when the water level is 350 cm

Fetal lung volume measurement by MRI with high-speed imaging systems

Energy Technology Data Exchange (ETDEWEB)

Osada, Hisao; Kaku, Kenshi [Chiba Univ. (Japan). Hospital

2002-08-01

Although ultrasonography is widely used for fetal morphologic observation, magnetic resonance imaging (MRI) has gained popularity as a new prenatal diagnostic method with recent introduction of high-speed imaging systems. Infants with lung hypoplasia affecting respiratory function require intensive management starting immediately after birth. Therefore, accurate prenatal differential diagnosis and severity evaluation are extremely important for these fetuses. The aim of this study is to measure fetal lung volume using a computer-based, three-dimensional MRI imaging system and to evaluate the possibility of clinical applications of this procedure. A total of 96 fetuses were evaluated, all were morphologically abnormal, and MRI was done for advanced assessment from 24 to 39 weeks gestation. Three-directional views of fetal chest were imaged by Signa Horizon, 1.5 Tesla, version 5.6 (General Electronics) with the following conditions; coil: TORSO coil, sequence: SSFSE (single shot fast spin echo), slice thickness: 5 mm, and imaging speed: 2 seconds/slice. To calculate the lung volume and create three-dimensional image, the lung area in each slice was traced out, then multiplied using computer image processing. Simultaneously, the volumes of all slices were summed to give the volume of each lung. Linear regression analysis and analysis of covariance (ANCOVA) were used for statistical analyses. In all cases, clear images were obtained, and were adequate for three-dimensional evaluation of the fetal lung. Thirty-five fetuses had poor outcomes, such as intrauterine fetal death, neonatal death, and intensive respiratory care. Regression lines of lung volume versus gestational week were calculated for these fetuses with poor outcome and 61 other fetuses with good outcome. ANCOVA, with gestational week as a covariant, revealed a significant intergroup difference in the lung volume (p<0.001). Similarly, regression lines of lung volume versus fetal body weight estimated by

Effect of high and low ultrafiltration volume during hemodialysis on relative blood volume

NARCIS (Netherlands)

Dasselaar, JJ; de Jong, PE; Huisman, RM; Franssen, CFM

2006-01-01

Achieving an optimal posthemodialysis hydration status may be difficult because objective criteria for dry weight are lacking. Both relative blood volume changes (Delta RBV) at the end of hemodialysis and Delta RBV normalized for ultrafiltration volume (Delta RBV/UF ratio) have been reported to

Lean Production Control at a High-Variety, Low-Volume Parts Manufacturer

NARCIS (Netherlands)

Bokhorst, Jos A. C.; Slomp, Jannes

2010-01-01

Eaton Electric General Supplies, a parts manufacturing unit that supplies parts for Eaton's electrical business unit, implemented several lean control elements in its high-variety, low-volume production units. These control elements include a constant work-in-process mechanism to limit and control

A flexible and accurate digital volume correlation method applicable to high-resolution volumetric images

Science.gov (United States)

Pan, Bing; Wang, Bo

2017-10-01

Digital volume correlation (DVC) is a powerful technique for quantifying interior deformation within solid opaque materials and biological tissues. In the last two decades, great efforts have been made to improve the accuracy and efficiency of the DVC algorithm. However, there is still a lack of a flexible, robust and accurate version that can be efficiently implemented in personal computers with limited RAM. This paper proposes an advanced DVC method that can realize accurate full-field internal deformation measurement applicable to high-resolution volume images with up to billions of voxels. Specifically, a novel layer-wise reliability-guided displacement tracking strategy combined with dynamic data management is presented to guide the DVC computation from slice to slice. The displacements at specified calculation points in each layer are computed using the advanced 3D inverse-compositional Gauss-Newton algorithm with the complete initial guess of the deformation vector accurately predicted from the computed calculation points. Since only limited slices of interest in the reference and deformed volume images rather than the whole volume images are required, the DVC calculation can thus be efficiently implemented on personal computers. The flexibility, accuracy and efficiency of the presented DVC approach are demonstrated by analyzing computer-simulated and experimentally obtained high-resolution volume images.

Ischemic Volume and Neurological Deficit: Correlation of Computed Tomography Perfusion with the National Institutes of Health Stroke Scale Score in Acute Ischemic Stroke.

Science.gov (United States)

Furlanis, Giovanni; Ajčević, Miloš; Stragapede, Lara; Lugnan, Carlo; Ridolfi, Mariana; Caruso, Paola; Naccarato, Marcello; Ukmar, Maja; Manganotti, Paolo

2018-04-30

The National Institutes of Health Stroke Scale (NIHSS) is the most adopted stroke patients' evaluation tool in emergency settings to assess the severity of stroke and to determine the patients' eligibility for specific treatments. Computed tomography perfusion (CTP) is crucial to identify salvageable tissue that can benefit from the reperfusion treatment. The aim of this study is to identify the relation between the NIHSS scores and the hypoperfused volumes evaluated by CTP in patients with hyperacute ischemic stroke. This retrospective study was conducted on 105 patients with ischemic stroke who underwent NIHSS assessment and CTP in the hyperacute phase. Hypoperfused volume was evaluated by CTP maps processed with semi-automatic algorithm. An analysis was conducted to determine the degree of correlation between the NIHSS scores and the ischemic lesion volumes and to investigate the relation between the anterior and the posterior circulation strokes, as well as between the right and the left hemispheric strokes. A significant correlation was found between ischemic volume and NIHSS score at baseline (r = .82; P correlation was identified in the anterior circulation stroke (r = .76; P correlated for the left and the right hemispheric strokes (r = .83 and .81; P correlation between the baseline NIHSS score and the ischemic volume estimated by CTP. We confirmed that NIHSS is a reliable predictor of perfusion deficits in acute ischemic stroke. CTP allows fast imaging assessment in the hyperacute phase. The results highlight the importance of these diagnostic tools in the assessment of stroke severity and in acute decision-making. Copyright © 2018 National Stroke Association. Published by Elsevier Inc. All rights reserved.

2016 Billion-Ton Report: Environmental Sustainability Effects of Select Scenarios from Volume 1 (Volume 2)

Energy Technology Data Exchange (ETDEWEB)

Efroymson, R. A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Langholtz, M. H. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Johnson, K. E. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Stokes, B. J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

2017-01-13

On behalf of all the authors and contributors, it is a great privilege to present the 2016 Billion-Ton Report (BT16), volume 2: Environmental Sustainability Effects of Select Scenarios from volume 1. This report represents the culmination of several years of collaborative effort among national laboratories, government agencies, academic institutions, and industry. BT16 was developed to support the U.S. Department of Energy’s efforts towards national goals of energy security and associated quality of life.

Development of alkali activated cements and concrete mixture design with high volumes of red mud

OpenAIRE

Krivenko, Pavel; Kovalchuk, Oleksandr; Pasko, Anton; Croymans, Tom; Hutt, Mikael; Lutter, Guillaume; Vandevenne, Niels; Schreurs, Sonja; Schroeyers, Wouter

2017-01-01

Dedicated cement compositions were formulated to enable the incorporation of large volume fractions of red mud in alkali activated cements, taking into account the role of the aluminosilicate phase in the processes of hydration and hardening. High volume red mud alkali activated cements were synthesized using a proper combination of red mud, low basic aluminosilicate compounds with a glass phase (blast-furnace slag) and additives selected from high-basic Ca-containing cements with a crystalli...

High-volume ovarian cancer care: survival impact and disparities in access for advanced-stage disease.

Science.gov (United States)

Bristow, Robert E; Chang, Jenny; Ziogas, Argyrios; Randall, Leslie M; Anton-Culver, Hoda

2014-02-01

To characterize the impact of hospital and physician ovarian cancer case volume on survival for advanced-stage disease and investigate socio-demographic variables associated with access to high-volume providers. Consecutive patients with stage IIIC/IV epithelial ovarian cancer (1/1/96-12/31/06) were identified from the California Cancer Registry. Disease-specific survival analysis was performed using Cox-proportional hazards model. Multivariate logistic regression analyses were used to evaluate for differences in access to high-volume hospitals (HVH) (≥20 cases/year), high-volume physicians (HVP) (≥10 cases/year), and cross-tabulations of high- or low-volume hospital (LVH) and physician (LVP) according to socio-demographic variables. A total of 11,865 patients were identified. The median ovarian cancer-specific survival for all patients was 28.2 months, and on multivariate analysis the HVH/HVP provider combination (HR = 1.00) was associated with superior ovarian cancer-specific survival compared to LVH/LVP (HR = 1.31, 95%CI = 1.16-1.49). Overall, 2119 patients (17.9%) were cared for at HVHs, and 1791 patients (15.1%) were treated by HVPs. Only 4.3% of patients received care from HVH/HVP, while 53.1% of patients were treated by LVH/LVP. Both race and socio-demographic characteristics were independently associated with an increased likelihood of being cared for by the LVH/LVP combination and included: Hispanic race (OR = 1.72, 95%CI = 1.22-2.42), Asian/Pacific Islander race (OR = 1.57, 95%CI = 1.07-2.32), Medicaid insurance (OR = 2.51, 95%CI = 1.46-4.30), and low socioeconomic status (OR = 2.84, 95%CI = 1.90-4.23). Among patients with advanced-stage ovarian cancer, the provider combination of HVH/HVP is an independent predictor of improved disease-specific survival. Access to high-volume ovarian cancer providers is limited, and barriers are more pronounced for patients with low socioeconomic status, Medicaid insurance, and racial minorities. Copyright © 2013

The ultrasound-guided retrolaminar block: volume-dependent injectate distribution

Directory of Open Access Journals (Sweden)

Damjanovska M

2018-02-01

Full Text Available Marija Damjanovska,1 Tatjana Stopar Pintaric,1,2 Erika Cvetko,2 Kamen Vlassakov3 1Clinical Department of Anesthesiology and Intensive Therapy, University Medical Centre Ljubljana, Ljubljana, Slovenia; 2Institute of Anatomy, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia; 3Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA Purpose: The ultrasound-guided retrolaminar block is one of the newer and simpler alternatives to the traditional, often technically challenging, paravertebral (PV block. Its feasibility, safety, and efficacy have already been clinically demonstrated in patients with multiple rib fractures using higher volumes of local anesthetic, when compared with the traditional approach. The primary aim of this observational anatomical study was to assess the spread of local anesthetic from the retrolaminar injection point to the PV space and its volume dependence. Second, we assessed the incidence of epidural and contralateral PV spread in the both groups.Methods: Ten fresh porcine cadavers were randomized into 2 groups (n=5 each to receive ultrasound-guided retrolaminar injections at Th4-Th5 level with either 10 mL (low-volume group or 30 mL (high-volume group of 2% lidocaine and methylene blue mixture. After the procedure, the cadavers were dissected and frozen. Cross-section cuts (~1 cm thick were performed to evaluate the injectate spread.Results: In the high-volume group, injectate spread from the retrolaminar to the PV space was observed in all specimens (5 out of 5; 100%, while in the low-volume group, no apparent spread to the PV space was found (0 out of 5; 0%. No epidural or contralateral PV spread was observed in any of the specimens.Conclusion: Following ultrasound-guided retrolaminar injections in fresh porcine cadavers, injectate spread from the retrolaminar tissue plane to the PV space is strongly volume dependent

High-level waste borosilicate glass: A compendium of corrosion characteristics. Volume 3

International Nuclear Information System (INIS)

Cunnane, J.C.

1994-03-01

The objective of this document is to summarize scientific information pertinent to evaluating the extent to which high-level waste borosilicate glass corrosion and the associated radionuclide release processes are understood for the range of environmental conditions to which waste glass may be exposed in service. Alteration processes occurring within the bulk of the glass (e.g., devitrification and radiation-induced changes) are discussed insofar as they affect glass corrosion. Volume III contains a bibliography of glass corrosion studies, including studies that are not cited in Volumes I and II

High-level waste borosilicate glass: A compendium of corrosion characteristics. Volume 3

Energy Technology Data Exchange (ETDEWEB)

Cunnane, J.C. [comp.; Bates, J.K.; Bradley, C.R. [Argonne National Lab., IL (United States)] [and others

1994-03-01

The objective of this document is to summarize scientific information pertinent to evaluating the extent to which high-level waste borosilicate glass corrosion and the associated radionuclide release processes are understood for the range of environmental conditions to which waste glass may be exposed in service. Alteration processes occurring within the bulk of the glass (e.g., devitrification and radiation-induced changes) are discussed insofar as they affect glass corrosion. Volume III contains a bibliography of glass corrosion studies, including studies that are not cited in Volumes I and II.

Exploring Institutional Transformations to Address High-End Climate Change in Iberia

Directory of Open Access Journals (Sweden)

Joan David Tàbara

2018-01-01

Full Text Available Either meeting the UNFCCC Paris agreement to limit global average warming below the 2–1.5 °C threshold, or going beyond it entails huge challenges in terms of institutional innovation and transformation. This research describes a participatory integrated assessment process aimed at exploring the options, opportunities, necessary capacities and implications for institutional co-operation and innovation in the Iberian Peninsula under High-End Climate Change (HECC. Using in-depth interviews and a novel participatory research approach, different scenario narratives and pathways about the future of Iberia have been identified using Shared Socio-economic Pathways (SSPs. Special attention is given to the knowledge and policy options needed to implement cross-border organizational changes and co-operation mechanisms that would support the Integrated Climate Governance of the Tagus and Guadiana river basins. We show that a wealth of institutional innovation pathways and specific options and solutions exist not only to reduce GHG emissions (mitigation and the negative impacts of climate change (adaptation, but, above all, to generate new forms of social-ecological system interactions aligned with sustainability (transformation. In particular, and depending on which scenario contexts unfold in the future in Iberia, different kinds of institutional and governance capacities and clusters of solutions may be needed in order to achieve transformation.

System of the advanced volume reduction facilities for LLW at JAERI

International Nuclear Information System (INIS)

Higuchi, Hidekazu; Monma, Toshiyuki; Nakashio, Nobuyuki; Kozawa, Kazushige; Touhei, Toshio; Sudou, Tomoyuki; Mitsuda, Motoyuki; Kurosawa, Shigenobu; Henmi, Kou; Ishikawa, Joji; Kato, Mitsugu; Sato, Motoaki

2005-01-01

The Japan Atomic Energy Research Institute (JAERI) constructed the Advanced Volume Reduction Facilities (AVRF), in which volume reduction techniques are applied and achieved high volume reduction ratio, homogenization and stabilization by means of melting or super compaction processes for low level solid wastes. It will be able to produce waste packages for final disposal and to reduce the amount of the wastes by operating the AVRF. The AVRF consist of the Waste Size Reduction and Storage Facilities (WSRSF) and the Waste Volume Reduction Facilities (WVRF); the former have cutting installations for large size wastes and the latter have melting units and a super compactor. Cutting installations in the WSRSF have been operating since June 1999. Radioactive wastes treated so far amount to 600 m 3 and the volume reduction ratio is from 1/2 to 1/3. The WVRF have been operating with non-radioactive wastes since February 2003 for the training and the homogeneity investigation in the melting processes. The operation with radioactive wastes will start in FY2005. (author)

Provider volume and outcomes for abdominal aortic aneurysm repair, carotid endarterectomy, and lower extremity revascularization procedures.

LENUS (Irish Health Repository)

Killeen, Shane D

2012-02-03

BACKGROUND: Intuitively, vascular procedures performed by high-volume vascular subspecialists working at high-volume institutions should be associated with improved patient outcome. Although a large number of studies assess the relationship between volume and outcome, a single contemporary compilation of such studies is lacking. METHODS: A review of the English language literature was performed incorporating searches of the Medline, EMBASE, and Cochrane collaboration databases for abdominal aortic aneurysm repair (elective and emergent), carotid endarterectomy, and arterial lower limb procedures for any volume outcome relationship. Studies were included if they involved a patient cohort from 1980 onwards, were community or population based, and assessed health outcomes (mortality and morbidity) as a dependent variable and volume as an independent variable. RESULTS: We identified 74 relevant studies, and 54 were included. All showed either an inverse relationship of variable magnitude between provider volume and mortality, or no volume-outcome effect. The reduction in the risk-adjusted mortality rate (RAMR) for high-volume providers was 3% to 11% for elective abdominal aortic aneurysm (AAA) repair, 2.5 to 5% for emergent AAA repair, 0.7% to 4.7% carotid endarterectomy, and 0.3% to 0.9% for lower limb arterial bypass procedures. Subspeciality training also conferred a considerable morbidity and mortality benefit for emergent AAA repair, carotid endarterectomy, and lower limb arterial procedures. CONCLUSION: High-volume providers have significantly better outcomes for vascular procedures both in the elective and emergent setting. Subspeciality training also has a considerable impact. These data provide further evidence for the specialization of vascular services, whereby vascular procedures should generally be preformed by high-volume, speciality trained providers.

Institut Max von Laue-Paul Langevin

International Nuclear Information System (INIS)

Whereas the first volume of the Annual Report gives a general survey of the activities of the different sections of the ILL (Institut Laue-Langevin), this second volume titled Annex to the 1975 annual report is dealing in more details with the scientific work carried out at the ILL from November the 1st 1974 to October the 1st 1975. Scientific works for which reports are available are presented grouped as possible, by college: theory; nuclear physics; excitations; structures; liquids, gas and amorphous materials; imperfections; physical biochemistry; and chemistry [fr

High-pitch dual-source CT coronary angiography with low volumes of contrast medium

Energy Technology Data Exchange (ETDEWEB)

Lembcke, Alexander; Hein, Patrick A.; Knobloch, Gesine; Durmus, Tahir; Hamm, Bernd [Charite - University Medicine Berlin, Department of Radiology, Berlin (Germany); Schwenke, Carsten [SCO:SSiS - Schwenke Consulting, Berlin (Germany); Huppertz, Alexander [Charite - University Medicine Berlin, Department of Radiology, Berlin (Germany); ISI - Imaging Science Institute Charite, Berlin (Germany)

2014-01-15

To assess the effect of lower volumes of contrast medium (CM) on image quality in high-pitch dual-source computed tomography coronary angiography (CTCA). One-hundred consecutive patients (body weight 65-85 kg, stable heart rate ≤65 bpm, cardiac index ≥2.5 L/min/m{sup 2}) referred for CTCA were prospectively enrolled. Patients were randomly assigned to one of five groups of different CM volumes (G{sub 30}, 30 mL; G{sub 40}, 40 mL; G{sub 50}, 50 mL; G{sub 60}, 60 mL; G{sub 70}, 70 mL; flow rate 5 mL/s each, iodine content 370 mg/mL). Attenuation within the proximal and distal coronary artery segments was analysed. Mean attenuation for men and women ranged from 345.0 and 399.1 HU in G{sub 30} to 478.2 and 571.8 HU in G{sub 70}. Mean attenuation values were higher in groups with higher CM volumes (P < 0.0001) and higher in women than in men (P < 0.0001). The proportions of segments with attenuation of at least 300 HU in G{sub 30}, G{sub 40}, G{sub 50}, G{sub 60} and G{sub 70} were 89 %, 95 %, 98 %, 98 % and 99 %. CM volume of 30 mL in women and 40 mL in men proved to be sufficient to guarantee attenuation of at least 300 HU. In selected patients high-pitch dual-source CTCA can be performed with CM volumes of 40 mL in men or 30 mL in women. (orig.)

Extended Excluded Volume: Its Origin and Consequences

Czech Academy of Sciences Publication Activity Database

Nezbeda, Ivo; Rouha, M.

2013-01-01

Roč. 85, č. 1 (2013), s. 201-210 ISSN 0033-4545. [International Conference on Solution Chemistry (ICSC-32) /32./. La Grande Motte, 28.08.2011-02.09.2011] R&D Projects: GA AV ČR IAA400720802 Institutional support: RVO:67985858 Keywords : excluded volume * partial molar volume * primitive models Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 3.112, year: 2013

Performance enhancement of direct ethanol fuel cell using Nafion composites with high volume fraction of titania

Science.gov (United States)

Matos, B. R.; Isidoro, R. A.; Santiago, E. I.; Fonseca, F. C.

2014-12-01

The present study reports on the performance enhancement of direct ethanol fuel cell (DEFC) at 130 °C with Nafion-titania composite electrolytes prepared by sol-gel technique and containing high volume fractions of the ceramic phase. It is found that for high volume fractions of titania (>10 vol%) the ethanol uptake of composites is largely reduced while the proton conductivity at high-temperatures is weakly dependent on the titania content. Such tradeoff between alcohol uptake and conductivity resulted in a boost of DEFC performance at high temperatures using Nafion-titania composites with high fraction of the inorganic phase.

Survival rate in nasopharyngeal carcinoma improved by high caseload volume: a nationwide population-based study in Taiwan

International Nuclear Information System (INIS)

Lee, Ching-Chih; Hung, Shih-Kai; Huang, Tze-Ta; Lee, Moon-Sing; Su, Yu-Chieh; Chou, Pesus; Hsiao, Shih-Hsuan; Chiou, Wen-Yen; Lin, Hon-Yi; Chien, Sou-Hsin

2011-01-01

Positive correlation between caseload and outcome has previously been validated for several procedures and cancer treatments. However, there is no information linking caseload and outcome of nasopharyngeal carcinoma (NPC) treatment. We used nationwide population-based data to examine the association between physician case volume and survival rates of patients with NPC. Between 1998 and 2000, a total of 1225 patients were identified from the Taiwan National Health Insurance Research Database. Survival analysis, the Cox proportional hazards model, and propensity score were used to assess the relationship between 10-year survival rates and physician caseloads. As the caseload of individual physicians increased, unadjusted 10-year survival rates increased (p < 0.001). Using a Cox proportional hazard model, patients with NPC treated by high-volume physicians (caseload ≥ 35) had better survival rates (p = 0.001) after adjusting for comorbidities, hospital, and treatment modality. When analyzed by propensity score, the adjusted 10-year survival rate differed significantly between patients treated by high-volume physicians and patients treated by low/medium-volume physicians (75% vs. 61%; p < 0.001). Our data confirm a positive volume-outcome relationship for NPC. After adjusting for differences in the case mix, our analysis found treatment of NPC by high-volume physicians improved 10-year survival rate

Positive and negative volume-outcome relationships in the geriatric trauma population.

Science.gov (United States)

Matsushima, Kazuhide; Schaefer, Eric W; Won, Eugene J; Armen, Scott B; Indeck, Matthew C; Soybel, David I

2014-04-01

In trauma populations, improvements in outcome are documented in institutions with higher case volumes. However, it is not known whether improved outcomes are attributable to the case volume within specific higher-risk groups, such as the elderly, or to the case volume among all trauma patients treated by an institution. To test the hypothesis that outcomes of trauma care for geriatric patients are affected differently by the volume of geriatric cases and nongeriatric cases of an institution. This retrospective cohort study using a statewide trauma registry was set in state-designated levels 1 and 2 trauma centers in Pennsylvania. It included 39 431 eligible geriatric trauma patients (aged >65 years) in the Pennsylvania Trauma Outcomes Study. In-hospital mortality, major complications, and mortality after major complications (failure to rescue). Between 2001 and 2010, 39 431 geriatric trauma patients and 105 046 nongeriatric patients were captured in a review of outcomes in 20 state-designated levels 1 and 2 trauma centers. Larger volumes of geriatric trauma patients were significantly associated with lower odds of in-hospital mortality, major complications, and failure to rescue. In contrast, larger nongeriatric trauma volumes were significantly associated with higher odds of major complications in geriatric patients. Higher rates of in-hospital mortality, major complications, and failure to rescue were associated with lower volumes of geriatric trauma care and paradoxically with higher volumes of trauma care for younger patients. These findings offer the possibility that outcomes might be improved with differentiated pathways of care for geriatric trauma patients.

Status on RF superconductivity at the institute for high energy physics

International Nuclear Information System (INIS)

Sevryukova, L.M.

2003-01-01

The development of SC cavities started at the Institute for High Energy Physics in September 1980 when the group of technology and study of SC cavities of the Research Institute of Nuclear Physics at Tomsk Polytechnic Institute moved there. At first the group worked at the Linear Accelerator Division, then later, in March 1993 the Federate Problem Laboratory for Technology and Study of the superconducting cavities of the Russian Atomic Ministry was founded at IHEP. The main goal of the SC cavity investigation is to study and develop the suppression methods for emission effects and conditions for thermomagnetic breakdown creation to increase the accelerating fields at SC cavities; also developing the experimental equipment to answer this goal. In this report the following items are enlightened in short: 1. Study and development of methods to suppress emission effects in SC cavities; 2. Study and development of methods to increase the threshold of the thermomagnetic breakdown. 3. Study of new materials and technologies. 4. SVAAP (SC accelerator for the applied purposes) project development. (author)

Financial institutions as an example of institutions of public trust

OpenAIRE

Agata Jakubowska

2013-01-01

Financial institutions are commonly known as institutions of public trust and they are fundamental for activities of other economic entities. The level of trust determines the competitive position of financial institutions. That is why care about the best standards is the most important task for these institutions. Financial institutions are called institutions of public trust and thus high professionalism and more responsibility is demanded from them. This article presents basic problems con...

Volume Bragg grating narrowed high-power and highly efficient cladding-pumped Raman fiber laser.

Science.gov (United States)

Liu, Jun; Yao, Weichao; Zhao, Chujun; Shen, Deyuan; Fan, Dianyuan

2014-12-10

High-power and highly efficient operation of a single-mode cladding-pumped Raman fiber laser with narrow lasing bandwidth is demonstrated. The spectral narrowing was realized by an external cavity containing a volume Bragg grating with a center wavelength of 1658 nm. A maximum output power of 10.4 W at 1658.3 nm with a spectral linewidth (FWHM) of ∼0.1  nm was obtained for the launched pump power of 18.4 W, corresponding to a slope efficiency of 109% with respect to the launched pump power. Lasing characteristics of free-running operation are also evaluated and discussed.

An introduction to the HighARCS Integrated Action Plans, with an institutions, policies and conflicts perspective

DEFF Research Database (Denmark)

Lund, Søren

This report is an introduction focused on institutions, policies and conflicts aspects, for the Integrated Action Plans (IAPs) produced by the HighARCS project for the 5 sites in China, India and Vietnam......This report is an introduction focused on institutions, policies and conflicts aspects, for the Integrated Action Plans (IAPs) produced by the HighARCS project for the 5 sites in China, India and Vietnam...

Adjustable mounting device for high-volume production of beam-shaping systems for high-power diode lasers

Science.gov (United States)

Haag, Sebastian; Bernhardt, Henning; Rübenach, Olaf; Haverkamp, Tobias; Müller, Tobias; Zontar, Daniel; Brecher, Christian

2015-02-01

In many applications for high-power diode lasers, the production of beam-shaping and homogenizing optical systems experience rising volumes and dynamical market demands. The automation of assembly processes on flexible and reconfigurable machines can contribute to a more responsive and scalable production. The paper presents a flexible mounting device designed for the challenging assembly of side-tab based optical systems. It provides design elements for precisely referencing and fixating two optical elements in a well-defined geometric relation. Side tabs are presented to the machine allowing the application of glue and a rotating mechanism allows the attachment to the optical elements. The device can be adjusted to fit different form factors and it can be used in high-volume assembly machines. The paper shows the utilization of the device for a collimation module consisting of a fast-axis and a slow-axis collimation lens. Results regarding the repeatability and process capability of bonding side tab assemblies as well as estimates from 3D simulation for overall performance indicators achieved such as cycle time and throughput will be discussed.

Forty years of the Institute for Nuclear Research (Scientific session of the Physical Sciences Division of the Russian Academy of Sciences, 22 December 2010)

International Nuclear Information System (INIS)

2011-01-01

On 22 December 2010, the scientific session of the Physical Sciences Division of the Russian Academy of Sciences (RAS), devoted to the 40th anniversary of the Institute for Nuclear Research, RAS, was held at the Institute for Nuclear Research, RAS in Troitsk. The agenda of the session announced on the website www.gpad.ac.ru of the RAS Physical Sciences Division listed the following reports: (1) Matveev V A (Institute for Nuclear Research, RAS, Moscow) ''Introductory word''; (2) Gavrin V N (Institute for Nuclear Research, RAS, Moscow) ''Contribution of the SAGE results to the understanding of solar physics and neutrino physics''; (3) Domogatsky G V (Institute for Nuclear Research, RAS, Moscow) ''Baikal neutrino experiment''; (4) Tkachev I I (Institute for Nuclear Research, RAS, Moscow) ''Observation of the Greisen - Zatsepin - Kuz'min effect at the Telescope Array Observatory''; (5) Kudenko Yu G (Institute for Nuclear Research, RAS, Moscow) ''Neutrino T2K experiment: the first results''; (6) Sadykov R A (Institute for Nuclear Research, RAS, Moscow) ''Fields of study of condensed media at the neutron facility at the INR, RAS''; (7) Zhuikov B L (Institute for Nuclear Research, RAS, Moscow) ''Production of isotopes at the INR, RAS: reality and prospects''. The papers written on the base of reports 1-5 and 7 are published below. In addition, the paper ''High-power diode-pumped alkali lasers'' by A M Shalagin is published. The paper is based on the report presented at the scientific session of the General Assembly of the Physical Sciences Division, RAS (13 December 2010) devoted to the 50th anniversary of the laser, the main materials of the session having been published in Usp. Fiz. Nauk 181 (8) 867 (2011) [Phys. Usp. 54 837 (2011)]. . Institute for Nuclear Research of the Russian Academy of Sciences turns 40, V A Matveev Physics-Uspekhi, 2011, Volume 54, Number 9, Pages 939-940 . The Russian-American gallium experiment SAGE, V N Gavrin Physics-Uspekhi, 2011, Volume 54

Is orbital volume associated with eyeball and visual cortex volume in humans?

Science.gov (United States)

Pearce, Eiluned; Bridge, Holly

2013-01-01

In humans orbital volume increases linearly with absolute latitude. Scaling across mammals between visual system components suggests that these larger orbits should translate into larger eyes and visual cortices in high latitude humans. Larger eyes at high latitudes may be required to maintain adequate visual acuity and enhance visual sensitivity under lower light levels. To test the assumption that orbital volume can accurately index eyeball and visual cortex volumes specifically in humans. Structural Magnetic Resonance Imaging (MRI) techniques are employed to measure eye and orbit (n = 88) and brain and visual cortex (n = 99) volumes in living humans. Facial dimensions and foramen magnum area (a proxy for body mass) were also measured. A significant positive linear relationship was found between (i) orbital and eyeball volumes, (ii) eyeball and visual cortex grey matter volumes and (iii) different visual cortical areas, independently of overall brain volume. In humans the components of the visual system scale from orbit to eye to visual cortex volume independently of overall brain size. These findings indicate that orbit volume can index eye and visual cortex volume in humans, suggesting that larger high latitude orbits do translate into larger visual cortices.

High Productivity DRIE solutions for 3D-SiP and MEMS Volume Manufacturing

International Nuclear Information System (INIS)

Puech, M; Thevenoud, J M; Launay, N; Arnal, N; Godinat, P; Andrieu, B; Gruffat, J M

2006-01-01

Emerging 3D-SiP technologies and high volume MEMS applications require high productivity mass production DRIE systems. The Alcatel DRIE product range has recently been optimised to reach the highest process and hardware production performances. A study based on sub-micron high aspect ratio structures encountered in the most stringent 3D-SiP has been carried out. The optimization of the Bosch process parameters has resulted in ultra high silicon etch rates, with unrivalled uniformity and repeatability leading to excellent process. In parallel, most recent hardware and proprietary design optimization including vacuum pumping lines, process chamber, wafer chucks, pressure control system, gas delivery are discussed. These improvements have been monitored in a mass production environment for a mobile phone application. Field data analysis shows a significant reduction of cost of ownership thanks to increased throughput and much lower running costs. These benefits are now available for all 3D-SiP and high volume MEMS applications. The typical etched patterns include tapered trenches for CMOS imagers, through silicon via holes for die stacking, well controlled profile angle for 3D high precision inertial sensors, and large exposed area features for inkjet printer heads and Silicon microphones

Evaluation of dose-volume histograms after prostate seed implantation. 4-year experience

International Nuclear Information System (INIS)

Hoinkis, C.; Lehmann, D.; Winkler, C.; Herrmann, T.; Hakenberg, O.W.; Wirth, M.P.

2004-01-01

Background and purpose: permanent interstitial brachytherapy by seed implantation is a treatment alternative for low-volume low-risk prostate cancer and a complex interdisciplinary treatment with a learning curve. Dose-volume histograms are used to assess postimplant quality. The authors evaluated their learning curve based on dose-volume histograms and analyzed factors influencing implantation quality. Patients and methods: since 1999, 38 patients with a minimum follow-up of 6 months were treated at the authors' institution with seed implantation using palladium-103 or iodine-125, initially using the preplan method and later real-time planning. Postimplant CT was performed after 4 weeks. The dose-volume indices D90, V100, V150, the D max of pre- and postplans, and the size and position of the volume receiving the prescribed dose (high-dose volume) of the postplans were evaluated. In six patients, postplan imaging both by CT and MRI was used and prostate volumes were compared with preimplant transrectal ultrasound volumes. The first five patients were treated under external supervision. Results: patients were divided into three consecutive groups for analysis of the learning curve (group 1: n = 5 patients treated under external supervision; group 2: n = 13 patients; group 3: n = 20 patients). D90 post for the three groups were 79.3%, 74.2%, and 99.9%, the V100 post were 78.6%, 73.5%, and 88.2%, respectively. The relationship between high-dose volume and prostate volume showed a similar increase as the D90, while the relationship between high-dose volume lying outside the prostate and prostate volume remained constant. The ratio between prostate volumes from transrectal ultrasound and CT imaging decreased with increasing D90 post , while the preplanning D90 and V100 remained constant. The different isotopes used, the method of planning, and the implanted activity per prostate volume did not influence results. Conclusion: a learning curve characterized by an increase

AIP study of multi-institutional collaborations: Phase 1, high-energy physics

International Nuclear Information System (INIS)

Warnow-Blewett, J.; Weart, S.R.

1992-01-01

Although the multi-institutional collaboration is increasingly the organizational framework for scientific research, it has received only incidental attention from scholars. Without a dedicated effort to understand the process of collaborative research, even the records necessary for efficient administration, for historical and: studies, and for posterity, will be largely scattered or destroyed. The Center for History of Physics of the American Institute of Physics (AIP) is working to redress this situation with a multi-stage investigation. The aim is to identify patterns of collaborations, define the scope of the documentation problems, field test possible solutions, and recommend future actions. The first phase of the study addressed high-energy physics. The two-year study of high-energy physics research focused on experiments approved between 1973 and 1984 at five of the world's major accelerator laboratories. A broad-scale picture of changes in the structure of collaborations was obtained by using databases on high energy physics experiments and publications, At a more detailed level, the project conducted interviews on 24 selected experimental collaborations. Still more detailed ''probes'' of some highly significant collaborations featured historical research as well as many additional interviews and work to preserve records. Some 300 interviews were analyzed to identify patterns of collaborative research and records creation, retention, and location. Meanwhile project staff surveyed the records-keeping practices of key physicists and made numerous site visits to accelerator facilities and university archives to discuss archival issues and records policies

THE ANALYSIS OF HIGH SCHOOL STUDENTS`BEHAVIOUR IN THE SELECTION OF HIGHER EDUCATION INSTITUTIONS

Directory of Open Access Journals (Sweden)

Irina SUSANU

2014-06-01

Full Text Available The paper is to examine the Romanian education system and it focuses on the most important aspects of the education marketing and marketing research. A survey instrument was designed to include the research upon high school student’s behavior in selecting a higher education institution. The results shown that the Romanian education system has some drawbacks, the most important being the weak implementation of marketing in the education institutions. Therefore, the purpose of the marketing researches is to establish a connection between the public which education services are dedicated to and the necessary information used to select a higher education institution.

High-energy molecular lasers self-controlled volume-discharge lasers and applications

CERN Document Server

Apollonov, V V

2016-01-01

This book displays the physics and design of high-power molecular lasers. The lasers described are self-controlled volume-discharge lasers. The book explains self-sustained discharge lasers, self-initiated discharge lasers and technical approaches to laser design. Important topics discussed are laser efficiency, laser beam quality and electric field homogeneity. The book contains many new innovative applications.

Summer Research Program - 1998 High School Apprenticeship Program. Volume 14. Phillips Laboratory

National Research Council Canada - National Science Library

Moore, Gary

1998-01-01

The United States Air Force Summer Research Program (USAF-SRP) is designed to introduce university, college, and technical institute faculty members, graduate students, and high school students to Air Force research...

Summer Research Program - 1998 High School Apprenticeship Program Volume 13 Rome Laboratory

National Research Council Canada - National Science Library

Moore, Gary

1998-01-01

The United States Air Force Summer Research Program (USAF-SRP) is designed to introduce university, college, and technical institute faculty members, graduate students, and high school students to Air Force research...

Summer Research Program - 1997 High School Apprenticeship Program. Volume 14, Rome Laboratory

National Research Council Canada - National Science Library

Moore, Gary

1997-01-01

The United States Air Force Summer Research Program (USAF-SRP) is designed to introduce university, college, and technical institute faculty members, graduate students, and high school students to Air Force research...

Summer Research Program - 1996 High School Apprenticeship Program Volume 13 Phillips Laboratory

National Research Council Canada - National Science Library

Moore, Gary

1996-01-01

The United States Air Force Summer Research Program (USAF-SRP) is designed to introduce university, college, and technical institute faculty members, graduate students, and high school students to Air Force research...

High volume ultrasound guided injections at the interface between the patellar tendon and Hoffa's body are effective in chronic patellar tendinopathy: A pilot study.

Science.gov (United States)

Crisp, Tom; Khan, Faisal; Padhiar, Nat; Morrissey, Dylan; King, John; Jalan, Rosy; Maffulli, Nicola; Frcr, Otto Chan

2008-01-01

To evaluate a novel conservative management modality for patellar tendinopathy. We recruited nine patients with patellar tendinopathy who had failed conservative management and showed evidence of neovascularisation on power Doppler scanning. A high volume ultrasound guided injection at the interface between the patellar tendon and Hoffa's body. The injection contained 10 ml 0.5% Bupivacaine, 25 mg Hydrocortisone, and between 12 and 40 ml normosaline. 100 mm visual analogue scales (VAS) for pain and for function, and Victorian Institute of Sport Assessment - Patellar tendon (VISA-P) questionnaires at an average of 9 months from the injection. All but one patient (whose pain was unchanged) improved (p = 0.028). The mean improvement in function 2 weeks after injection was 58 mm on VAS (interquartile range 27 - 88, p = 0.018). The mean improvement in pain 2 weeks after injection was 56 mm on a VAS scale (interquartile range 32 - 80, p = 0.018). At a mean follow up of 9 months, an improvement of 22 points from a baseline score of 46 on the VISA-P questionnaire (100 being normal) was established. High volume injections to mechanically disrupt the neovascularisation in patellar tendinopathy are helpful in the management of this condition. Controlled trials would be warranted to investigate in a more conclusive fashion this management modality.

77 FR 21065 - Certain High Production Volume Chemicals; Test Rule and Significant New Use Rule; Fourth Group of...

Science.gov (United States)

2012-04-09

... 2070-AJ66 Certain High Production Volume Chemicals; Test Rule and Significant New Use Rule; Fourth... an opportunity to comment on a proposed test rule for 23 high production volume (HPV) chemical... necessary, to prohibit or limit that activity before it occurs. The opportunity to present oral comment was...

Association Between Treatment at a High-Volume Facility and Improved Survival for Radiation-Treated Men With High-Risk Prostate Cancer

Energy Technology Data Exchange (ETDEWEB)

Chen, Yu-Wei [Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women' s Hospital, Boston, Massachusetts (United States); Mahal, Brandon A. [Department of Medicine, Brigham and Women' s Hospital, Boston, Massachusetts (United States); Harvard Medical School, Boston, Massachusetts (United States); Muralidhar, Vinayak [Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women' s Hospital, Boston, Massachusetts (United States); Harvard Medical School, Boston, Massachusetts (United States); Nezolosky, Michelle [Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women' s Hospital, Boston, Massachusetts (United States); Beard, Clair J. [Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women' s Hospital, Boston, Massachusetts (United States); Harvard Medical School, Boston, Massachusetts (United States); Den, Robert B. [Department of Radiation Oncology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania (United States); Feng, Felix Y. [Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, Michigan (United States); Hoffman, Karen E. [Department of Radiation Oncology, the University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Martin, Neil E.; Orio, Peter F. [Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women' s Hospital, Boston, Massachusetts (United States); Harvard Medical School, Boston, Massachusetts (United States); Nguyen, Paul L., E-mail: pnguyen@LROC.harvard.edu [Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women' s Hospital, Boston, Massachusetts (United States); Harvard Medical School, Boston, Massachusetts (United States)

2016-03-15

Purpose: Although the association between higher hospital volume and improved outcomes has been well-documented in surgery, there is little data about whether this effect exists for radiation-treated patients. We investigated whether treatment at a radiation facility that treats a high volume of prostate cancer patients is associated with improved survival for men with high-risk prostate cancer. Methods and Materials: We used the National Cancer Database (NCDB) to identity patients diagnosed with prostate cancer from 2004 to 2006. The radiation case volume (RCV) of each hospital was based on its number of radiation-treated prostate cancer patients. We used propensity-score based analysis to compare the overall survival (OS) of high-risk prostate cancer patients in high versus low RCV hospitals. Primary endpoint is overall survival. Covariates adjusted for were tumor characteristics, sociodemographic factors, radiation type, and use of androgen deprivation therapy (ADT). Results: A total of 19,565 radiation-treated high-risk patients were identified. Median follow-up was 81.0 months (range: 1-108 months). When RCV was coded as a continuous variable, each increment of 100 radiation-managed patients was associated with improved OS (adjusted hazard ratio [AHR]: 0.97; 95% confidence interval [CI]: 0.95-0.98; P<.0001) after adjusting for known confounders. For illustrative purposes, when RCV was dichotomized at the 80th percentile (43 patients/year), high RCV was associated with improved OS (7-year overall survival 76% vs 74%, log-rank test P=.0005; AHR: 0.91, 95% CI: 0.86-0.96, P=.0005). This association remained significant when RCV was dichotomized at 75th (37 patients/year), 90th (60 patients/year), and 95th (84 patients/year) percentiles but not the 50th (19 patients/year). Conclusions: Our results suggest that treatment at centers with higher prostate cancer radiation case volume is associated with improved OS for radiation-treated men with high-risk prostate

Just-in-Time Training for High-Risk Low-Volume Therapies: An Approach to Ensure Patient Safety.

Science.gov (United States)

Helman, Stephanie; Lisanti, Amy Jo; Adams, Ann; Field, Cynthia; Davis, Katherine Finn

2016-01-01

High-risk low-volume therapies are those therapies that are practiced infrequently and yet carry an increased risk to patients because of their complexity. Staff nurses are required to competently manage these therapies to treat patients' unique needs and optimize outcomes; however, maintaining competence is challenging. This article describes implementation of Just-in-Time Training, which requires validation of minimum competency of bedside nurses managing high-risk low-volume therapies through direct observation of a return-demonstration competency checklist.

High Center Volume Does Not Mitigate Risk Associated with Using High Donor Risk Organs in Liver Transplantation.

Science.gov (United States)

Beal, Eliza W; Black, Sylvester M; Mumtaz, Khalid; Hayes, Don; El-Hinnawi, Ashraf; Washburn, Kenneth; Tumin, Dmitry

2017-09-01

High-risk donor allografts increase access to liver transplant, but potentially reduce patient and graft survival. It is unclear whether the risk associated with using marginal donor livers is mitigated by increasing center experience. The United Network for Organ Sharing registry was queried for adult first-time liver transplant recipients between 2/2002 and 12/2015. High donor risk was defined as donor risk index >1.9, and 1-year patient and graft survival were compared according to donor risk index in small and large centers. Multivariable Cox regression estimated the hazard ratio (HR) associated with using high-risk donor organs, according to a continuous measure of annual center volume. The analysis included 51,770 patients. In 67 small and 67 large centers, high donor risk index predicted increased mortality (p = 0.001). In multivariable analysis, high-donor risk index allografts predicted greater mortality hazard at centers performing 20 liver transplants per year (HR 1.35; 95% CI 1.22, 1.49; p donor risk index and center volume was not statistically significant (p = 0.747), confirming that the risk associated with using marginal donor livers was comparable between smaller and larger centers. Results were consistent when examining graft loss. At both small and large centers, high-risk donor allografts were associated with reduced patient and graft survival after liver transplant. Specific strategies to mitigate the risk of liver transplant involving high-risk donors are needed, in addition to accumulation of center expertise.

VOLUME STUDY WITH HIGH DENSITY OF PARTICLES BASED ON CONTOUR AND CORRELATION IMAGE ANALYSIS

Directory of Open Access Journals (Sweden)

Tatyana Yu. Nikolaeva

2014-11-01

Full Text Available The subject of study is the techniques of particle statistics evaluation, in particular, processing methods of particle images obtained by coherent illumination. This paper considers the problem of recognition and statistical accounting for individual images of small scattering particles in an arbitrary section of the volume in case of high concentrations. For automatic recognition of focused particles images, a special algorithm for statistical analysis based on contouring and thresholding was used. By means of the mathematical formalism of the scalar diffraction theory, coherent images of the particles formed by the optical system with high numerical aperture were simulated. Numerical testing of the method proposed for the cases of different concentrations and distributions of particles in the volume was performed. As a result, distributions of density and mass fraction of the particles were obtained, and the efficiency of the method in case of different concentrations of particles was evaluated. At high concentrations, the effect of coherent superposition of the particles from the adjacent planes strengthens, which makes it difficult to recognize images of particles using the algorithm considered in the paper. In this case, we propose to supplement the method with calculating the cross-correlation function of particle images from adjacent segments of the volume, and evaluating the ratio between the height of the correlation peak and the height of the function pedestal in the case of different distribution characters. The method of statistical accounting of particles considered in this paper is of practical importance in the study of volume with particles of different nature, for example, in problems of biology and oceanography. Effective work in the regime of high concentrations expands the limits of applicability of these methods for practically important cases and helps to optimize determination time of the distribution character and

An Approach to Energy Education for High School, Junior High School and Elementary School Students at Aichi Institute of Technology

Science.gov (United States)

Yukita, Kazuto; Ichiyanagi, Katsuhiro; Mori, Tsuyoshi; Goto, Yasuyuki

This paper discusses the methods of implementation and improvement adopted in the energy education program of “Marugoto Taiken World” (“Total Experience World”) at Aichi Institute of Technology. The program, which is aimed at high school, junior high school and elementary school students, has been carried on at Aichi Institute of Technology for a number of years now, and the authors have been involved in the energy education project for the past four years. During that time, the following four courses have been held : 1) Let's use wind power to generate electricity, 2) Let's use flowers to build a solar battery, 3) Let's use bottles to build a fuel cell battery, 4) Let's make all sorts of batteries.

High-level waste storage tank farms/242-A evaporator Standards/Requirements Identification Document (S/RID), Volume 4

Energy Technology Data Exchange (ETDEWEB)

1994-04-01

The High-Level Waste Storage Tank Farms/242-A Evaporator Standards/Requirements Identification Document (S/RID) is contained in multiple volumes. This document (Volume 4) presents the standards and requirements for the following sections: Radiation Protection and Operations.

High-level waste storage tank farms/242-A evaporator Standards/Requirements Identification Document (S/RID), Volume 4

International Nuclear Information System (INIS)

1994-04-01

The High-Level Waste Storage Tank Farms/242-A Evaporator Standards/Requirements Identification Document (S/RID) is contained in multiple volumes. This document (Volume 4) presents the standards and requirements for the following sections: Radiation Protection and Operations

Computerized 50 liter volume calibration system

International Nuclear Information System (INIS)

Proffitt, T.H.

1990-01-01

A system has been designed for the Savannah River Site that will be used to calibrate product shipping containers. For accountability purposes, it is necessary that these containers be calibrated to a very high precision. The Computerized 50 Liter Volume Calibration System (CVCS), which is based on the Ideal Gas Law (IGL), will use reference volumes with precision of no less ±0.03%, and helium to calibrate the containers to have a total error of no greater than ±0.10%. A statistical interpretation of the system has given a theoretical total calculated error of ±0.08%. Tests with the system will be performed once fabrication is complete to experimentally verify the calculated error. Since the total error was calculated using the worst case scenario, the actual error should be significantly less than the calculated value. The computer controlled, totally automated system is traceable to the National Institute of Standards and Technology. The design, calibration procedure, and statistical interpretation of the system will be discussed. 1 ref

Laboratory Investigations on Mechanical Properties of High Volume Fly Ash Concrete and Composite Sections

OpenAIRE

Aravindkumar B. Harwalkar; S. S. Awanti

2013-01-01

Use of fly ash as a supplementary cementing material in large volumes can bring both technological and economic benefits for concrete industry. In this investigation mix proportions for high volume fly ash concrete were determined at cement replacement levels of 50%, 55%, 60% and 65% with low calcium fly ash. Flexural and compressive strengths of different mixes were measured at ages of 7, 28 and 90 days. Flexural strength of composite section prepared from pavement quali...

Characteristics of potential repository wastes: Volume 4, Appendix 4A, Nuclear reactors at educational institutions of the United States; Appendix 4B, Data sheets for nuclear reactors at educational institutions; Appendix 4C, Supplemental data for Fort St. Vrain spent fuel; Appendix 4D, Supplemental data for Peach Bottom 1 spent fuel; Appendix 4E, Supplemental data for Fast Flux Test Facility

International Nuclear Information System (INIS)

1992-07-01

Volume 4 contains the following appendices: nuclear reactors at educational institutions in the United States; data sheets for nuclear reactors at educational institutions in the United States(operational reactors and shut-down reactors); supplemental data for Fort St. Vrain spent fuel; supplemental data for Peach Bottom 1 spent fuel; and supplemental data for Fast Flux Test Facility

High-level waste storage tank farms/242-A evaporator Standards/Requirements Identification Document (S/RID), Volume 5

International Nuclear Information System (INIS)

1994-04-01

The High-Level Waste Storage Tank Farms/242-A Evaporator Standards/Requirements Identification Document (S/RID) is contained in multiple volumes. This document (Volume 5) outlines the standards and requirements for the Fire Protection and Packaging and Transportation sections

Optimal hypofractionated conformal radiotherapy for large brain metastases in patients with high risk factors: a single-institutional prospective study

International Nuclear Information System (INIS)

Inoue, Hiroshi K; Sato, Hiro; Suzuki, Yoshiyuki; Saitoh, Jun-ichi; Noda, Shin-ei; Seto, Ken-ichi; Torikai, Kota; Sakurai, Hideyuki; Nakano, Takashi

2014-01-01

A single-institutional prospective study of optimal hypofractionated conformal radiotherapy for large brain metastases with high risk factors was performed based on the risk prediction of radiation-related complications. Eighty-eight patients with large brain metastases ≥10 cm 3 in critical areas treated from January 2010 to February 2014 using the CyberKnife were evaluated. The optimal dose and number of fractions were determined based on the surrounding brain volume circumscribed with a single dose equivalent (SDE) of 14 Gy (V14) to be less than 7 cm 3 for individual lesions. Univariate and multivariate analyses were conducted. As a result of optimal treatment, 92 tumors ranging from 10 to 74.6 cm 3 (median, 16.2 cm 3 ) in volume were treated with a median prescribed isodose of 57% and a median fraction number of five. In order to compare the results according to the tumor volume, the tumors were divided into the following three groups: 1) 10–19.9 cm 3 , 2) 20–29.9 cm 3 and 3) ≥30 cm 3 . The lesions were treated with a median prescribed isodose of 57%, 56% and 55%, respectively, and the median fraction number was five in all three groups. However, all tumors ≥20 cm 3 were treated with ≥ five fractions. The median SDE of the maximum dose in the three groups was 47.2 Gy, 48.5 Gy and 46.5 Gy, respectively. Local tumor control was obtained in 90.2% of the patients, and the median survival was nine months, with a median follow-up period of seven months (range, 3-41 months). There were no significant differences in the survival rates among the three groups. Six tumors exhibited marginal recurrence 7-36 months after treatment. Ten patients developed symptomatic brain edema or recurrence of pre-existing edema, seven of whom required osmo-steroid therapy. No patients developed radiation necrosis requiring surgical resection. Our findings demonstrate that the administration of optimal hypofractionated conformal radiotherapy based on the dose-volume prediction

EUV mask defect inspection and defect review strategies for EUV pilot line and high volume manufacturing

Science.gov (United States)

Chan, Y. David; Rastegar, Abbas; Yun, Henry; Putna, E. Steve; Wurm, Stefan

2010-04-01

Reducing mask blank and patterned mask defects is the number one challenge for extreme ultraviolet lithography. If the industry succeeds in reducing mask blank defects at the required rate of 10X every year for the next 2-3 years to meet high volume manufacturing defect requirements, new inspection and review tool capabilities will soon be needed to support this goal. This paper outlines the defect inspection and review tool technical requirements and suggests development plans to achieve pilot line readiness in 2011/12 and high volume manufacturing readiness in 2013. The technical specifications, tooling scenarios, and development plans were produced by a SEMATECH-led technical working group with broad industry participation from material suppliers, tool suppliers, mask houses, integrated device manufacturers, and consortia. The paper summarizes this technical working group's assessment of existing blank and mask inspection/review infrastructure capabilities to support pilot line introduction and outlines infrastructure development requirements and tooling strategies to support high volume manufacturing.

TTI Phase 2 Institutional Support: Indian Institute of Dalit Studies ...

International Development Research Centre (IDRC) Digital Library (Canada)

This funding will enhance the Indian Institute of Dalit Studies' (IIDS) role as a credible public policy institution in India by strengthening its ability to provide high-quality, influential, and policy-relevant research. About the Indian Institute of Dalit Studies IIDS is a social sciences research centre with a focus on development ...

Proceedings of the 1984 workshop on high-energy excitations in condensed matter. Volume II

International Nuclear Information System (INIS)

Silver, R.N.

1984-12-01

This volume covers electronic excitations, momentum distributions, high energy photons, and a wrap-up session. Abstracts of individual items from the conference were prepared separately for the data base

Scoping studies to reduce ICPP high-level radioactive waste volumes for final disposal

International Nuclear Information System (INIS)

Knecht, D.A.; Berreth, J.R.; Chipman, N.A.; Cole, H.S.; Geczi, L.S.; Kerr, W.B.; Staples, B.A.

1985-08-01

This report presents the results of scoping studies carried out to determine the feasibility of the following candidate options to reduce high-level waste volume: (1) low-fluoride, low-volume glass, (2) glass-ceramic and ceramic, (3) Modified Zirflex, (4) inerts removal by neutralization, and (5) modified Fluorinel processes. The results of the scoping studies show that the glass-ceramic/ceramic waste forms and neutralization process with potential HLW volume reductions ranging from 60 to 80% appear feasible, based on laboratory-scale tests. The presently used Fluorinel process modified by reducing HF usage also appears to be feasible and could result in up to a 10% potential volume reduction. If the current process start-up tests verify the practicality, reduced HF usage will be implemented. The low-volume glass and Modified Zirflex processes may also be feasible, based on laboratory tests, but would require significantly more process development and/or modifications and could result in only a 20 to 30% potential volume reduction. Based on these scoping studies, it is recommended that (1) the glass-ceramic/ceramic and neutralization processes be developed further, (2) reduced HF use for the Modified Fluorinel process be implemented as soon as practical and other options reducing chemical usage for criticality control be evaluated, (3) basic development for the glass process be continued as a back-up technology, and (4) laboratory-scale radioactive fuel dissolution testing for the Modified Zirflex process be completed with further process development discontinued unless needed in the future

Communications Strategies on Alcohol and Highway Safety. Volume II. High School Youth. Final Report.

Science.gov (United States)

Grey Advertising, Inc., New York, NY.

The second part of a two-part, two volume study deals with high school youth and identifies target populations and communications strategies for encouraging personal action steps to prevent drunk driving. Data, collected from interviews and questionnaires, are summarized and presented in tabular form. One fourth of high schoolers in a…

High-level waste storage tank farms/242-A evaporator Standards/Requirements Identification Document (S/RID), Volume 2

International Nuclear Information System (INIS)

1994-04-01

The High-Level Waste Storage Tank Farms/242-A Evaporator Standards/Requirements Document (S/RID) is contained in multiple volumes. This document (Volume 2) presents the standards and requirements for the following sections: Quality Assurance, Training and Qualification, Emergency Planning and Preparedness, and Construction

High-level waste storage tank farms/242-A evaporator Standards/Requirements Identification Document (S/RID), Volume 2

Energy Technology Data Exchange (ETDEWEB)

1994-04-01

The High-Level Waste Storage Tank Farms/242-A Evaporator Standards/Requirements Document (S/RID) is contained in multiple volumes. This document (Volume 2) presents the standards and requirements for the following sections: Quality Assurance, Training and Qualification, Emergency Planning and Preparedness, and Construction.

Bones and Brexit: The Past and the Future Introduction to PIA Volume 26/27

Directory of Open Access Journals (Sweden)

Clare Lewis

2017-12-01

Full Text Available On behalf of the editorial team we are delighted to introduce volumes 26 & 27 of Papers from the Institute of Archaeology. The contributions in this joint volume were intentionally edited together to encompass the diverse range of research undertaken at UCL Institute of Archaeology. The context to this research environment is provided in the forum covering archaeological and heritage sector implications of Britain’s vote in 2016 to leave the European Union. We also introduce three new projects in this joint volume as a new dynamic to Papers from the Institute of Archaeology. The interview has an audio recording accessible in the online version, the winning poster from our poster competition accompanies this editorial, and the first of a series of ‘Postcards from Qatar’ is also presented.

Porosity of Self-Compacting Concrete (SCC) incorporating high volume fly ash

Science.gov (United States)

Kristiawan, S. A.; Sunarmasto; Murti, G. Y.

2017-02-01

Degradation of concrete could be triggered by the presence of aggressive agents from the environment into the body of concrete. The penetration of these agents is influenced by the pore characteristics of the concrete. Incorporating a pozzolanic material such as fly ash could modify the pore characteristic of the concrete. This research aims to investigate the influence of incorporating fly ash at high volume level on the porosity of Self-Compacting Concrete (SCC). Laboratory investigations were carried out following the ASTM C642 for measuring density and volume of permeable pores (voids) of the SCC with varying fly ash contents (50-70% by weight of total binder). In addition, a measurement of permeable voids by saturation method was carried out to obtain an additional volume of voids that could not be measured by the immersion and boiling method of ASTM C642. The results show that the influence of fly ash content on the porosity appears to be dependent on age of SCC. At age less than 56 d, fly ash tends to cause an increase of voids but at 90 d of age it reduces the pores. The additional pores that can be penetrated by vacuum saturation method counts about 50% of the total voids.

Reachable volume RRT

KAUST Repository

McMahon, Troy

2015-05-01

© 2015 IEEE. Reachable volumes are a new technique that allows one to efficiently restrict sampling to feasible/reachable regions of the planning space even for high degree of freedom and highly constrained problems. However, they have so far only been applied to graph-based sampling-based planners. In this paper we develop the methodology to apply reachable volumes to tree-based planners such as Rapidly-Exploring Random Trees (RRTs). In particular, we propose a reachable volume RRT called RVRRT that can solve high degree of freedom problems and problems with constraints. To do so, we develop a reachable volume stepping function, a reachable volume expand function, and a distance metric based on these operations. We also present a reachable volume local planner to ensure that local paths satisfy constraints for methods such as PRMs. We show experimentally that RVRRTs can solve constrained problems with as many as 64 degrees of freedom and unconstrained problems with as many as 134 degrees of freedom. RVRRTs can solve problems more efficiently than existing methods, requiring fewer nodes and collision detection calls. We also show that it is capable of solving difficult problems that existing methods cannot.

Reachable volume RRT

KAUST Repository

McMahon, Troy; Thomas, Shawna; Amato, Nancy M.

2015-01-01

© 2015 IEEE. Reachable volumes are a new technique that allows one to efficiently restrict sampling to feasible/reachable regions of the planning space even for high degree of freedom and highly constrained problems. However, they have so far only been applied to graph-based sampling-based planners. In this paper we develop the methodology to apply reachable volumes to tree-based planners such as Rapidly-Exploring Random Trees (RRTs). In particular, we propose a reachable volume RRT called RVRRT that can solve high degree of freedom problems and problems with constraints. To do so, we develop a reachable volume stepping function, a reachable volume expand function, and a distance metric based on these operations. We also present a reachable volume local planner to ensure that local paths satisfy constraints for methods such as PRMs. We show experimentally that RVRRTs can solve constrained problems with as many as 64 degrees of freedom and unconstrained problems with as many as 134 degrees of freedom. RVRRTs can solve problems more efficiently than existing methods, requiring fewer nodes and collision detection calls. We also show that it is capable of solving difficult problems that existing methods cannot.

Effect of High-Temperature Curing Methods on the Compressive Strength Development of Concrete Containing High Volumes of Ground Granulated Blast-Furnace Slag

Directory of Open Access Journals (Sweden)

Wonsuk Jung

2017-01-01

Full Text Available This paper investigates the effect of the high-temperature curing methods on the compressive strength of concrete containing high volumes of ground granulated blast-furnace slag (GGBS. GGBS was used to replace Portland cement at a replacement ratio of 60% by binder mass. The high-temperature curing parameters used in this study were the delay period, temperature rise, peak temperature (PT, peak period, and temperature down. Test results demonstrate that the compressive strength of the samples with PTs of 65°C and 75°C was about 88% higher than that of the samples with a PT of 55°C after 1 day. According to this investigation, there might be optimum high-temperature curing conditions for preparing a concrete containing high volumes of GGBS, and incorporating GGBS into precast concrete mixes can be a very effective tool in increasing the applicability of this by-product.

Biotreatment of produced waters for volume reduction and contaminant removal

Energy Technology Data Exchange (ETDEWEB)

Negri, M.C.; Hinchman, R.R. [Argonne National Lab., IL (United States); Mollock, J. [Devon Energy Corp., Oklahoma City, OK (United States)

1997-10-01

Produced water is wastewater that is brought to the surface from natural gas wells during natural gas production. Its constituents, mostly salt, with traces of hydrocarbons and heavy metals, are a significant disposal problem. Argonne National Laboratory (ANL), in partnership with the Gas Research Institute (GRI), has developed a low-cost, low-tech method, in which green plants are used to reduce the volume of produced water. The authors have designed an engineered bioreactor system, which is modeled after natural saline wetland ecosystems. The plant bioreactor system maximizes plant evapotranspiration to reduce wastewater volume and, concurrently, may function as a biological filter to enhance contaminant degradation and immobilization in the root/rhizosphere zone. Halophyte plant species having high salt tolerance and high transpiration rates were selected after they tested them in greenhouse experiments. Models obtained by using their greenhouse findings reduced the volume of the wastewater (up to 6% salt) by 75% in about 8 days. A field demonstration of the bioreactor, designed on the basis of the results from the greenhouse study, is successfully under way at a natural gas well site in Oklahoma. The process could offer the petroleum industry a low-cost biological alternative to existing expensive options.

76 FR 28807 - High Pressure Steel Cylinders From China; Institution of Antidumping and Countervailing Duty...

Science.gov (United States)

2011-05-18

... the United States is materially retarded, by reason of imports from China of High Pressure Steel... INTERNATIONAL TRADE COMMISSION [Investigation Nos. 701-TA-480 and 731-TA-1188 (Preliminary)] High Pressure Steel Cylinders From China; Institution of Antidumping and Countervailing Duty Investigations and...

Survival rate in nasopharyngeal carcinoma improved by high caseload volume: a nationwide population-based study in Taiwan

Directory of Open Access Journals (Sweden)

Chou Pesus

2011-08-01

Full Text Available Abstract Background Positive correlation between caseload and outcome has previously been validated for several procedures and cancer treatments. However, there is no information linking caseload and outcome of nasopharyngeal carcinoma (NPC treatment. We used nationwide population-based data to examine the association between physician case volume and survival rates of patients with NPC. Methods Between 1998 and 2000, a total of 1225 patients were identified from the Taiwan National Health Insurance Research Database. Survival analysis, the Cox proportional hazards model, and propensity score were used to assess the relationship between 10-year survival rates and physician caseloads. Results As the caseload of individual physicians increased, unadjusted 10-year survival rates increased (p p = 0.001 after adjusting for comorbidities, hospital, and treatment modality. When analyzed by propensity score, the adjusted 10-year survival rate differed significantly between patients treated by high-volume physicians and patients treated by low/medium-volume physicians (75% vs. 61%; p Conclusions Our data confirm a positive volume-outcome relationship for NPC. After adjusting for differences in the case mix, our analysis found treatment of NPC by high-volume physicians improved 10-year survival rate.

Contradictions in the American dream: High educational aspirations and perceptions of deteriorating institutional support.

Science.gov (United States)

Aronson, Pamela

2017-02-01

This study examines contradictions in the "American Dream" during the Great Recession: young adults maintained high educational aspirations, yet perceived little opportunity for their educational achievements to help them fulfil their dreams of financial prosperity and work stability. Based on in-depth interviews with 85 young college students and recent graduates, this study found that college enrolment was propelled by the recession, as a college degree, and often a graduate or professional degree, was perceived as an increasingly necessary credential. Despite these high educational aspirations, students and recent graduates were fearful about their capacity to find future work and they expressed concerns about the collapse of employment opportunity. Many were also wary of educational institutions, which they viewed as unable to prepare them for a shrinking job market. These perceptions reveal a contradiction in the "American Dream:" although young adults have high aspirations and achievements, they have lost confidence in the educational and work institutions upon which they must depend. © 2016 International Union of Psychological Science.

Summer Research Program - 1996 High School Apprenticeship Program Volume 15A Wright Laboratory

National Research Council Canada - National Science Library

Moore, Gary

1996-01-01

The United States Air Force Summer Research Program (USAF-SRP) is designed to introduce university, college, and technical institute faculty members, graduate students, and high school students to Air Force research...

Summer Research Program - 1996 High School Apprenticeship Program. Volume 12B, Armstrong Laboratory

National Research Council Canada - National Science Library

Moore, Gary

1996-01-01

The United States Air Force Summer Research Program (USAF-SRP) is designed to introduce university, college, and technical institute faculty members, graduate students, and high school students to Air Force research...

Summer Research Program - 1998 High School Apprenticeship Program Volume 15C Wright Laboratory

National Research Council Canada - National Science Library

Moore, Gary

1998-01-01

The United States Air Force Summer Research Program (USAF-SRP) is designed to introduce university, college, and technical institute faculty members, graduate students, and high school students to Air Force research...

Summer Research Program - 1998 High School Apprenticeship Program Volume 15B Wright Laboratory

National Research Council Canada - National Science Library

Moore, Gary

1998-01-01

The United States Air Force Summer Research Program (USAF-SRP) is designed to introduce university, college, and technical institute faculty members, graduate students, and high school students to Air Force research...

High initial tidal volumes in emergency department patients at risk for acute respiratory distress syndrome.

Science.gov (United States)

Allison, Michael G; Scott, Michael C; Hu, Kami M; Witting, Michael D; Winters, Michael E

2015-04-01

Emergency department (ED) patients are at high risk for the acute respiratory distress syndrome (ARDS). Settings only 1 mL/kg above recommended tidal volumes confers harm for these patients. The purpose of this study was to determine whether ED physicians routinely initiate mechanical ventilation with low tidal volumes in patients at risk for ARDS. We retrospectively reviewed the charts of all adult patients who were intubated in an urban, academic ED. The charts were analyzed to identify patients in whom ARDS developed within 48 hours after ED admission. Patients were eligible for inclusion if they had bilateral infiltrates on imaging, had a Pao2/Fio2 ratio less than 300 mm Hg and did not have heart failure contributing to their presentation. The tidal volumes set in the ED were then compared with the recommended tidal volume of 6 mL/kg of predicted body weight. The initial tidal volumes set in the ED were higher than recommended by an average of 80 mL (95% confidence interval, 60-110, P tidal volume ventilation setting. In an academic, tertiary hospital, newly intubated ED patients in whom ARDS developed within 48 hours after intubation were ventilated with tidal volumes that exceeded recommendations by an average of 1.5 mL/kg. Copyright © 2014 Elsevier Inc. All rights reserved.

High level waste storage tank farms/242-A evaporator Standards/Requirements Identification Document (S/RID), Volume 6

Energy Technology Data Exchange (ETDEWEB)

1994-04-01

The High-Level Waste Storage Tank Farms/242-A Evaporator Standards/Requirements Identification Document (S/RID) is contained in multiple volumes. This document (Volume 6) outlines the standards and requirements for the sections on: Environmental Restoration and Waste Management, Research and Development and Experimental Activities, and Nuclear Safety.

High level waste storage tank farms/242-A evaporator Standards/Requirements Identification Document (S/RID), Volume 6

International Nuclear Information System (INIS)

1994-04-01

The High-Level Waste Storage Tank Farms/242-A Evaporator Standards/Requirements Identification Document (S/RID) is contained in multiple volumes. This document (Volume 6) outlines the standards and requirements for the sections on: Environmental Restoration and Waste Management, Research and Development and Experimental Activities, and Nuclear Safety

Comments on H- volume production in Cs-seeded ion sources. Appendix I

International Nuclear Information System (INIS)

Peterson, J.R.

1986-01-01

Considerable interest was generated at the IAEA Negative Ion Beam Workshop in Grenoble, France, in March, 1985, by a report from the Kurchatov Institute on the development of a 2-ampere steady-state H - ion source, in which the ions were volume-produced in a discharge in H 2 , seeded with Cs vapor. The mechanism primarily responsible for this remarkably high current from a volume production source was not yet understood, but it was tentatively presumed to involve the collisional energy transfer from electronically excited Cs 6p atoms into H 2 vibrations. In any case, it was apparently different from the surface-plasma interactions that have been assumed to control the H - production in the Dudnikov-Dimov type sources

Dose volume assessment of high dose rate 192IR endobronchial implants

International Nuclear Information System (INIS)

Cheng, B. Saw; Korb, Leroy J.; Pawlicki, Todd; Wu, Andrew

1996-01-01

Purpose: To study the dose distributions of high dose rate (HDR) endobronchial implants using the dose nonuniformity ratio (DNR) and three volumetric irradiation indices. Methods and Materials: Multiple implants were configured by allowing a single HDR 192 Ir source to step through a length of 6 cm along an endobronchial catheter. Dwell times were computed to deliver a dose of 5 Gy to points 1 cm away from the catheter axis. Five sets of source configurations, each with different dwell position spacings from 0.5 to 3.0 cm, were evaluated. Three-dimensional (3D) dose distributions were then generated for each source configuration. Differential and cumulative dose-volume curves were generated to quantify the degree of target volume coverage, dose nonuniformity within the target volume, and irradiation of tissues outside the target volume. Evaluation of the implants were made using the DNR and three volumetric irradiation indices. Results: The observed isodose distributions were not able to satisfy all the dose constraints. The ability to optimally satisfy the dose constraints depended on the choice of dwell position spacing and the specification of the dose constraint points. The DNR and irradiation indices suggest that small dwell position spacing does not result in a more homogeneous dose distribution for the implant. This study supports the existence of a relationship between the dwell position spacing and the distance from the catheter axis to the reference dose or dose constraint points. Better dose homogeneity for an implant can be obtained if the spacing of the dwell positions are about twice the distance from the catheter axis to the reference dose or dose constraint points

PATRAM '80. Proceedings. Volume 1

International Nuclear Information System (INIS)

Huebner, H.W.

1980-01-01

Volume 1 contains papers from the following sessions: Plenary Session; Regulations, Licensing and Standards; LMFBR Systems Concepts; Risk/Safety Assessment I; Systems and Package Design; US Institutional Issues; Risk/Safety Assessment II; Leakage, Leak Rate and Seals; Poster Session A; Operations and Systems Experience I; Manufacturing Processes and Materials; and Quality Assurance and Maintenance. Individual papers were processed. (LM)

A Study on the Evaluation of Field Application of High-Fluidity Concrete Containing High Volume Fly Ash

Directory of Open Access Journals (Sweden)

Yun-Wang Choi

2015-01-01

Full Text Available In the recent concrete industry, high-fluidity concrete is being widely used for the pouring of dense reinforced concrete. Normally, in the case of high-fluidity concrete, it includes high binder contents, so it is necessary to replace part of the cement through admixtures such as fly ash to procure economic feasibility and durability. This study shows the mechanical properties and field applicability of high-fluidity concrete using mass of fly ash as alternative materials of cement. The high-fluidity concrete mixed with 50% fly ash was measured to manufacture concrete that applies low water/binder ratio to measure the mechanical characteristics as compressive strength and elastic modulus. Also, in order to evaluate the field applicability, high-fluidity concrete containing high volume fly ash was evaluated for fluidity, compressive strength, heat of hydration, and drying shrinkage of concrete.

Institute of Nuclear Materials Management 36. annual meeting: Proceedings. Volume 24

International Nuclear Information System (INIS)

Anon.

1995-01-01

The sessions at this meeting covered the following topics: international safeguards; physical protection; material control and accountability (MC and A) training; waste overview; nonproliferation and arms control -- US/former Soviet Union; MC and A/physical protection -- SNM storage; spent fuel storage; physical protection -- intrusion sensors and access delay; MC and A -- gamma ray and holdup measurements; MC and A -- neutron based measurements; MC and A/nonproliferation and arms control -- fissile materials disposition; low level waste; packaging and transportation; international safeguards and nonproliferation and arms control -- IAEA verification in the US; international safeguards and physical protection -- video systems; poster and demonstrations; international safeguards and physical protection -- T.I.D.'s, tags and seals; high level wastes and mixed waste; MC and A -- bulk measurements; MC and A and physical protection -- policy; nonproliferation and arms control -- detection and monitoring techniques; nonproliferation and arms control -- US-Russian lab-to-lab safeguards cooperation; MC and A -- information systems; physical protection and MC and A -- vulnerability assessments; waste management -- measurement; international safeguards -- integrated and remote monitoring systems; MC and A -- material control and accountability and indicators; nonproliferation and arms control -- treaties and analysis; nonproliferation and arms control -- plutonium/HEU nonproliferation; MC and A -- measurement control and verification; and international safeguards and nonproliferation and arms control -- environmental monitoring and export control. Separate abstracts were prepared for some of the papers in this volume

Natural gas annual 1994: Volume 2

International Nuclear Information System (INIS)

1995-11-01

The Natural Gas Annual provides information on the supply and disposition of natural gas to a wide audience including industry, consumers, Federal and State agencies, and educational institutions. This report, Volume 2, presents historical data fro the Nation from 1930 to 1994, and by State from 1967 to 1994

Natural gas annual 1994: Volume 2

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-11-01

The Natural Gas Annual provides information on the supply and disposition of natural gas to a wide audience including industry, consumers, Federal and State agencies, and educational institutions. This report, Volume 2, presents historical data fro the Nation from 1930 to 1994, and by State from 1967 to 1994.

Forschungszentrum Rossendorf, Institute of Ion Beam Physics and Materials Research. Annual Report 1994

International Nuclear Information System (INIS)

Moeller, W.; Wieser, E.; Kirch, S.

1995-03-01

This volume contains the 1994 annual report describing the scientific activity of the Institute of Ion Beam Physics and Material Research (Forschungszentrum Rossendorf, FZR). This institute is devoted to the application of ion beams for the modification and analysis of near-surface layers of solids. (MSA)

8th International Summer Institute in Surface Science

CERN Document Server

Howe, Russell

1988-01-01

This volume contains review articles written by the invited speakers at the eighth International Summer Institute in Surface Science (ISISS 1987), held at the University of Wisconsin-Milwaukee in August of 1987. During the course of ISISS, invited speakers, all internationally recognized experts in the various fields of surface science, present tutorial review lectures. In addition, these experts are asked to write review articles on their lecture topic. Former ISISS speakers serve as advisors concerning the selection of speakers and lecture topics. Em­ phasis is given to those areas which have not been covered in depth by recent Summer Institutes, as well as to areas which have recently gained in significance and in which important progress has been made. Because of space limitations, no individual volume of Chemistry and Physics of Solid Surfaces can possibly cover the whole area of modem surface science, or even give a complete survey of recent pro­ gress in the field. However, an attempt is made to pres...

7th International Summer Institute in Surface Science

CERN Document Server

Howe, Russell

1986-01-01

This volume contains review articles which were written by the invited speak­ ers of the seventh International Summer Institute in Surface Science (ISISS), held at the University of Wisconsin - Milwaukee in July 1985. The form of ISISS is a set of tutorial review lectures presented over a one-week period by internationally recognized experts on various aspects of surface science. Each speaker is asked, in addition, to write a review article on his lecture topic. No single volume in the series Chemistry and Physics of Solid Surfaces can possibly cover the entire field of modern surface science. However, the series as a whole is intended to provide experts and students alike with a comprehensive set of reviews and literature references, particularly empha­ sizing the gas-solid interface. The collected articles from previous Summer Institutes have been published under the following titles: Surface Science: Recent Progress and Perspectives, Crit. Rev. Solid State Sci. 4, 125-559 (1974) Chemistry and Physics of ...

Volume doubling time and growth rate of renal cell carcinoma determined by helical CT: a single-institution experience

International Nuclear Information System (INIS)

Lee, Ji Young; Kim, Chan Kyo; Choi, Dongil; Park, Byung Kwan

2008-01-01

The purpose of this study was to retrospectively evaluate the volume doubling time (VDT) and growth rate of renal cell carcinomas (RCC) on a serial computed tomography (CT) scan. Thirty pathologically proven RCCs were reviewed with helical CT. Each tumor underwent at least two CT scans. Tumor volume was determined using an area measuring tool and the summation-of-areas technique. Growth rate was evaluated in terms of diameter and volume changes. VDT and volume growth rate were compared in relation to several factors (initial diameter, initial volume, diameter growth rate, volume growth rate, tumor grade, tumor subtype, sex or age). Mean VDT of RCCs was 505 days. Mean diameter and volume growth rate were 0.59 cm/year and 19.1 cm 3 /year, respectively. For volume and diameter growth rate, tumors ≤4 cm showed lower rates than those >4 cm (P 0.05). Volume growth rate was moderately to strongly positively correlated with initial diameter, initial volume and diameter growth rate (P < 0.05). In conclusion, small RCCs grew at a slow rate both diametrically and volumetrically. More accurate assessment of tumor growth rate and VDT may be helpful to understand the natural history of RCC. (orig.)

Volume measurement of thalami in normal Chinese Han nationality adults by the high-resolution MRI

International Nuclear Information System (INIS)

Ma Shuai; Chen Nan; Guo Yulin

2012-01-01

Objective: To measure the volume of thalamus in 1000 healthy Chinese Han nationality adults, and to analyze the relationship between thalamic volume and age, sex, weight and cerebral volume, to provide reliable data for the construction of database of Chinese adults' digital standard brain. Methods: Totally 1000 healthy Chinese adults of Han nationality aged from 18 to 80 years were recruited.They were divided into 5 groups by age: 18-30, 31-40, 41-50, 51-60 and 61-80 years. Each group included 100 males and 100 females. Brain images were obtained on a 1.5 T MR, and the outline of thalami was drawn with Aquariusws software. Then the thalamic volume was calculated automatically. The volumes of left and right thalamus were compared by paired sample t-test. Thalamic volumes of the same side were compared between males and females by independent sample t-test. And thalamic volumes of different age groups were compared by one-way ANOVA. The relationships between thalamic volume and age, sex, weight and cerebral volume were analyzed respectively. Results: The males' standardized volumes of left and right thalamus of healthy Chinese Han nationality adults were (5776 ± 780), (5655 ± 759) mm 3 , and they were (5464 ±573), (5360 ± 542) mm 3 for female. The males' thalamic volume was more than the females' on the same side (t=2.245, 2.200, P<0.01). The left thalamic volumes of various age groups were (6180 ± 534), (6047 ± 562), (5426 ± 471), (5552 ± 526), (4866 ± 552) mm 3 , respectively, while the right thalamic volumes of the 5 groups were (6069 ± 532), (5895 ± 539), (5357 ± 480), (5396 ± 445),(4791 ± 558)mm 3 , respectively. There were statistically significant difference among the 5 groups (F=165.686, 165.235, P<0.01). The left and right thalamic volume were all negatively correlated with age (r=-0.633, -0.645, P<0.05). Conclusions: With high resolution 1.5 T MR scanner,grey matter and white matter can be depicted clearly and the outline

Survey of Biomass Gasification, Volume II: Principles of Gasification

Energy Technology Data Exchange (ETDEWEB)

Reed, T.B. (comp.)

1979-07-01

Biomass can be converted by gasification into a clean-burning gaseous fuel that can be used to retrofit existing gas/oil boilers, to power engines, to generate electricity, and as a base for synthesis of methanol, gasoline, ammonia, or methane. This survey describes biomass gasification, associated technologies, and issues in three volumes. Volume I contains the synopsis and executive summary, giving highlights of the findings of the other volumes. In Volume II the technical background necessary for understanding the science, engineering, and commercialization of biomass is presented. In Volume III the present status of gasification processes is described in detail, followed by chapters on economics, gas conditioning, fuel synthesis, the institutional role to be played by the federal government, and recommendations for future research and development.

Water Stress from High-Volume Hydraulic Fracturing Potentially Threatens Aquatic Biodiversity and Ecosystem Services in Arkansas, United States.

Science.gov (United States)

Entrekin, Sally; Trainor, Anne; Saiers, James; Patterson, Lauren; Maloney, Kelly; Fargione, Joseph; Kiesecker, Joseph; Baruch-Mordo, Sharon; Konschnik, Katherine; Wiseman, Hannah; Nicot, Jean-Philippe; Ryan, Joseph N

2018-02-20

Demand for high-volume, short duration water withdrawals could create water stress to aquatic organisms in Fayetteville Shale streams sourced for hydraulic fracturing fluids. We estimated potential water stress using permitted water withdrawal volumes and actual water withdrawals compared to monthly median, low, and high streamflows. Risk for biological stress was considered at 20% of long-term median and 10% of high- and low-flow thresholds. Future well build-out projections estimated potential for continued stress. Most water was permitted from small, free-flowing streams and "frack" ponds (dammed streams). Permitted 12-h pumping volumes exceeded median streamflow at 50% of withdrawal sites in June, when flows were low. Daily water usage, from operator disclosures, compared to median streamflow showed possible water stress in 7-51% of catchments from June-November, respectively. If 100% of produced water was recycled, per-well water use declined by 25%, reducing threshold exceedance by 10%. Future water stress was predicted to occur in fewer catchments important for drinking water and species of conservation concern due to the decline in new well installations and increased use of recycled water. Accessible and precise withdrawal and streamflow data are critical moving forward to assess and mitigate water stress in streams that experience high-volume withdrawals.

Water stress from high-volume hydraulic fracturing potentially threatens aquatic biodiversity and ecosystem services in Arkansas, United States

Science.gov (United States)

Entrekin, Sally; Trainor, Anne; Saiers, James; Patterson, Lauren; Maloney, Kelly O.; Fargione, Joseph; Kiesecker, Joseph M.; Baruch-Mordo, Sharon; Konschnik, Katherine E.; Wiseman, Hannah; Nicot, Jean-Philippe; Ryan, Joseph N.

2018-01-01

Demand for high-volume, short duration water withdrawals could create water stress to aquatic organisms in Fayetteville Shale streams sourced for hydraulic fracturing fluids. We estimated potential water stress using permitted water withdrawal volumes and actual water withdrawals compared to monthly median, low, and high streamflows. Risk for biological stress was considered at 20% of long-term median and 10% of high- and low-flow thresholds. Future well build-out projections estimated potential for continued stress. Most water was permitted from small, free-flowing streams and “frack” ponds (dammed streams). Permitted 12-h pumping volumes exceeded median streamflow at 50% of withdrawal sites in June, when flows were low. Daily water usage, from operator disclosures, compared to median streamflow showed possible water stress in 7–51% of catchments from June–November, respectively. If 100% of produced water was recycled, per-well water use declined by 25%, reducing threshold exceedance by 10%. Future water stress was predicted to occur in fewer catchments important for drinking water and species of conservation concern due to the decline in new well installations and increased use of recycled water. Accessible and precise withdrawal and streamflow data are critical moving forward to assess and mitigate water stress in streams that experience high-volume withdrawals.

High failure rates after (131)I therapy in Graves hyperthyroidism patients with large thyroid volumes, high iodine uptake, and high iodine turnover.

Science.gov (United States)

de Jong, Jeroen A F; Verkooijen, Helena M; Valk, Gerlof D; Zelissen, Pierre M J; de Keizer, Bart

2013-06-01

The objective of this study was to identify patient characteristics positively and independently associated with I-iodide treatment failure in a large cohort of patients with Graves hyperthyroidism treated with either a calculated "standard" activity of 3.7 MBq/mL (0.1 mCi) or 7.4 MBq/mL (0.2 mCi) of thyroid volume. Data on 385 consecutive patients were prospectively collected. Clinical treatment outcome up to 1 year in relation to thyroid volume, 5- and 24-hour I uptake, 5/24-hour I uptake ratio, and the administered activity of radioiodine were analyzed. Overall treatment results were hypothyroidism in 46%, euthyroidism in 29%, and recurrent hyperthyroidism in 26% of patients. Thyroid volume (P = 0.000), 5/24-hour uptake ratio (P = 0.000), and 5- and 24-hour uptake alone (respectively, P = 0.000 and P = 0.002) were significantly associated with therapy outcome. Patients with a combination of a thyroid volume greater than 50 mL and a 5/24-hour uptake ratio 0.8 or greater showed treatment failure in 70% and 42% (respectively, 3.7 MBq/mL, n = 20; and 7.4 MBq/mL, n = 41).Thyroid volume and 5/24-hour uptake ratio were positively and independently associated with recurrent hyperthyroidism (respectively, odds ratio [OR], 5.3; 95% confidence interval [CI], 2.39-11.76; and OR, 2.97; 95% CI, 1.59-5.59). Higher activities of 7.4 MBq/mL I were associated with a lower risk of treatment failure (OR, 0.34; 95% CI, 0.18-0.62). Large thyroid volumes and high 5/24-hour uptake ratios are positively and independently associated with recurrent hyperthyroidism following I therapy in Graves hyperthyroidism. Higher success rates can be achieved when account is taken of these poor prognostic factors. In consequence, these patients should be treated with activities greater than 7.4 MBq/mL.

History of CERN. Volume 3

International Nuclear Information System (INIS)

Krige, J.

1996-01-01

The present volume continues the story of the history of the European Organization for Nuclear Research (CERN) in Geneva, Switzerland, concentrating on the years between the mid 1960s and the late 1970s. Whereas the first two volumes were the product of a team of historians, this book is rather a collection of studies by authors with very different professional backgrounds and institutional locations. It also differs from the predecessor volumes in the fact that it consists of distinct case studies dealing with a number of issues deemed important. The first part of this volume, containing contributions by historians of science, perceives the laboratory as being at the node of a complex of interconnected relationships between scientists and science managers on the staff, the users in the member states, and the governments which were called upon to finance the laboratory. In part 2 the physical results, obtained at CERN, are surveyed, while in part 3 two chapters are presented, one on engineering and technology, and the other on the research and development of electronic position detectors

PATRAM '80. Proceedings. Volume 2

International Nuclear Information System (INIS)

Huebner, H.W.

1980-01-01

Volume 2 contains papers from the following sessions: Safeguards-Related Problems; Neutronics and Criticality; Operations and Systems Experience II; Plutonium Systems; Intermediate Storage in Casks; Operations and Systems Planning; Institutional Issues; Structural and Thermal Evaluation I; Poster Session B; Extended Testing I; Structural and Thermal Evaluation II; Extended Testing II; and Emergency Preparedness and Response. Individual papers were processed. (LM)

Amygdalar, hippocampal, and thalamic volumes in youth at high risk for development of bipolar disorder.

Science.gov (United States)

Karchemskiy, Asya; Garrett, Amy; Howe, Meghan; Adleman, Nancy; Simeonova, Diana I; Alegria, Dylan; Reiss, Allan; Chang, Kiki

2011-12-30

Children of parents with bipolar disorder (BD), especially those with attention deficit hyperactivity disorder (ADHD) and symptoms of depression or mania, are at significantly high risk for developing BD. As we have previously shown amygdalar reductions in pediatric BD, the current study examined amygdalar volumes in offspring of parents (BD offspring) who have not yet developed a full manic episode. Youth participating in the study included 22 BD offspring and 22 healthy controls of comparable age, gender, handedness, and IQ. Subjects had no history of a manic episode, but met criteria for ADHD and moderate mood symptoms. MRI was performed on a 3T GE scanner, using a 3D volumetric spoiled gradient echo series. Amygdalae were manually traced using BrainImage Java software on positionally normalized brain stacks. Bipolar offspring had similar amygdalar volumes compared to the control group. Exploratory analyses yielded no differences in hippocampal or thalamic volumes. Bipolar offspring do not show decreased amygdalar volume, possibly because these abnormalities occur after more prolonged illness rather than as a preexisting risk factor. Longitudinal studies are needed to determine whether amygdalar volumes change during and after the development of BD. 2011 Elsevier Ireland Ltd. All rights reserved.

Zooplankton biomass data (displacement volume, wet mass, and dry mass) collected by the Sea Fisheries Research Institute (SFRI) in the active upwelling zone on the west coast of South Africa 1969-12-02 to 1969-12-16 (NODC Accession 0071850)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Zooplankton biomass data (displacement volume, wet mass, and dry mass) collected by South African the Sea Fisheries Research Institute (SFRI) during SFRI upwelling...

Statistical evaluation of the mechanical properties of high-volume class F fly ash concretes

KAUST Repository

Yoon, Seyoon; Monteiro, Paulo J.M.; Macphee, Donald E.; Glasser, Fredrik P.; Imbabi, Mohammed Salah-Eldin

2014-01-01

the authors experimentally and statistically investigated the effects of mix-design factors on the mechanical properties of high-volume class F fly ash concretes. A total of 240 and 32 samples were produced and tested in the laboratory to measure compressive

Cross-correlations in volume space: Differences between buy and sell volumes

Science.gov (United States)

Lee, Sun Young; Hwang, Dong Il; Kim, Min Jae; Koh, In Gyu; Kim, Soo Yong

2011-03-01

We study the cross-correlations of buy and sell volumes on the Korean stock market in high frequency. We observe that the pulling effects of volumes are as small as that of returns. The properties of the correlations of buy and sell volumes differ. They are explained by the degree of synchronization of stock volumes. Further, the pulling effects on the minimal spanning tree are studied. In minimal spanning trees with directed links, the large pulling effects are clustered at the center, not uniformly distributed. The Epps effect of buy and sell volumes are observed. The reversal of the cross-correlations of buy and sell volumes is also detected.

Ageless Aluminum-Cerium-Based Alloys in High-Volume Die Casting for Improved Energy Efficiency

Science.gov (United States)

Stromme, Eric T.; Henderson, Hunter B.; Sims, Zachary C.; Kesler, Michael S.; Weiss, David; Ott, Ryan T.; Meng, Fanqiang; Kassoumeh, Sam; Evangelista, James; Begley, Gerald; Rios, Orlando

2018-04-01

Strong chemical reactions between Al and Ce lead to the formation of intermetallics with exceptional thermal stability. The rapid formation of intermetallics directly from the liquid phase during solidification of Al-Ce alloys leads to an ultrafine microconstituent structure that effectively strengthens as-cast alloys without further microstructural optimization via thermal processing. Die casting is a high-volume manufacturing technology that accounts for greater than 40% of all cast Al products, whereas Ce is highly overproduced as a waste product of other rare earth element (REE) mining. Reducing heat treatments would stimulate significant improvements in manufacturing energy efficiency, exceeding (megatonnes/year) per large-scale heat-treatment line. In this study, multiple compositions were evaluated with wedge mold castings to test the sensitivity of alloys to the variable solidification rate inherent in high-pressure die casting. Once a suitable composition was determined, it was successfully demonstrated at 800 lbs/h in a 600-ton die caster, after which the as-die cast parts performed similarly to ubiquitous A380 in the same geometry without requiring heat treatment. This work demonstrates the compatibility of Al REE alloys with high-volume die-casting applications with minimal heat treatments.

Ageless Aluminum-Cerium-Based Alloys in High-Volume Die Casting for Improved Energy Efficiency

Science.gov (United States)

Stromme, Eric T.; Henderson, Hunter B.; Sims, Zachary C.; Kesler, Michael S.; Weiss, David; Ott, Ryan T.; Meng, Fanqiang; Kassoumeh, Sam; Evangelista, James; Begley, Gerald; Rios, Orlando

2018-06-01

Strong chemical reactions between Al and Ce lead to the formation of intermetallics with exceptional thermal stability. The rapid formation of intermetallics directly from the liquid phase during solidification of Al-Ce alloys leads to an ultrafine microconstituent structure that effectively strengthens as-cast alloys without further microstructural optimization via thermal processing. Die casting is a high-volume manufacturing technology that accounts for greater than 40% of all cast Al products, whereas Ce is highly overproduced as a waste product of other rare earth element (REE) mining. Reducing heat treatments would stimulate significant improvements in manufacturing energy efficiency, exceeding (megatonnes/year) per large-scale heat-treatment line. In this study, multiple compositions were evaluated with wedge mold castings to test the sensitivity of alloys to the variable solidification rate inherent in high-pressure die casting. Once a suitable composition was determined, it was successfully demonstrated at 800 lbs/h in a 600-ton die caster, after which the as-die cast parts performed similarly to ubiquitous A380 in the same geometry without requiring heat treatment. This work demonstrates the compatibility of Al REE alloys with high-volume die-casting applications with minimal heat treatments.

Adoption of lean principles in a high-volume molecular diagnostic microbiology laboratory.

Science.gov (United States)

Mitchell, P Shawn; Mandrekar, Jayawant N; Yao, Joseph D C

2014-07-01

Clinical laboratories are constantly facing challenges to do more with less, enhance quality, improve test turnaround time, and reduce operational expenses. Experience with adopting and applying lean concepts and tools used extensively in the manufacturing industry is described for a high-volume clinical molecular microbiology laboratory, illustrating how operational success and benefits can be achieved. Copyright © 2014, American Society for Microbiology. All Rights Reserved.

Reference book for the nitrogen industry worker in two volumes, volume 1

Science.gov (United States)

1982-05-01

The first volume presents the physical and chemical properties of gaseous and liquid substances used and obtained at the nitrogen industry enterprises. It describes the different methods for producing and purifying production gases (nitrogen-hydrogen mixture, gas synthesis). It examines the physical and chemical properties of the processes of amonia and methanol synthesis, the industrial plans and the principles for automating them. Certain methods are given for technological calculations, characteristics of the catalysts are presented, and the employed equipment is described. It is designed for engineering-technical workers of enterprises of the nitrogen and other sectors of industry, for specialists working in the scientific research and planning institutes, design offices and other organizations, as well as for teachers of higher educational institutions and students specializing in the field of the technology of inorganic products.

Characterization of segmented large volume, high purity germanium detectors

International Nuclear Information System (INIS)

Bruyneel, B.

2006-01-01

γ-ray tracking in future HPGe arrays like AGATA will rely on pulse shape analysis (PSA) of multiple γ-interactions. For this purpose, a simple and fast procedure was developed which enabled the first full characterization of a segmented large volume HPGe detector. An analytical model for the hole mobility in a Ge crystal lattice was developed to describe the hole drift anisotropy with experimental velocity values along the crystal axis as parameters. The new model is based on the drifted Maxwellian hole distribution in Ge. It is verified by reproducing successfully experimental longitudinal hole anisotropy data. A comparison between electron and hole mobility shows large differences for the longitudinal and tangential velocity anisotropy as a function of the electrical field orientation. Measurements on a 12 fold segmented, n-type, large volume, irregular shaped HPGe detector were performed in order to determine the parameters of anisotropic mobility for electrons and holes as charge carriers created by γ-ray interactions. To characterize the electron mobility the complete outer detector surface was scanned in small steps employing photopeak interactions at 60 keV. A precise measurement of the hole drift anisotropy was performed with 356 keV rays. The drift velocity anisotropy and crystal geometry cause considerable rise time differences in pulse shapes depending on the position of the spatial charge carrier creation. Pulse shapes of direct and transient signals are reproduced by weighting potential calculations with high precision. The measured angular dependence of rise times is caused by the anisotropic mobility, crystal geometry, changing field strength and space charge effects. Preamplified signals were processed employing digital spectroscopy electronics. Response functions, crosstalk contributions and averaging procedures were taken into account implying novel methods due to the segmentation of the Ge-crystal and the digital electronics. The results are

Characterization of segmented large volume, high purity germanium detectors

Energy Technology Data Exchange (ETDEWEB)

Bruyneel, B. [Koeln Univ. (Germany). Inst. fuer Kernphysik

2006-07-01

{gamma}-ray tracking in future HPGe arrays like AGATA will rely on pulse shape analysis (PSA) of multiple {gamma}-interactions. For this purpose, a simple and fast procedure was developed which enabled the first full characterization of a segmented large volume HPGe detector. An analytical model for the hole mobility in a Ge crystal lattice was developed to describe the hole drift anisotropy with experimental velocity values along the crystal axis as parameters. The new model is based on the drifted Maxwellian hole distribution in Ge. It is verified by reproducing successfully experimental longitudinal hole anisotropy data. A comparison between electron and hole mobility shows large differences for the longitudinal and tangential velocity anisotropy as a function of the electrical field orientation. Measurements on a 12 fold segmented, n-type, large volume, irregular shaped HPGe detector were performed in order to determine the parameters of anisotropic mobility for electrons and holes as charge carriers created by {gamma}-ray interactions. To characterize the electron mobility the complete outer detector surface was scanned in small steps employing photopeak interactions at 60 keV. A precise measurement of the hole drift anisotropy was performed with 356 keV rays. The drift velocity anisotropy and crystal geometry cause considerable rise time differences in pulse shapes depending on the position of the spatial charge carrier creation. Pulse shapes of direct and transient signals are reproduced by weighting potential calculations with high precision. The measured angular dependence of rise times is caused by the anisotropic mobility, crystal geometry, changing field strength and space charge effects. Preamplified signals were processed employing digital spectroscopy electronics. Response functions, crosstalk contributions and averaging procedures were taken into account implying novel methods due to the segmentation of the Ge-crystal and the digital electronics

Evolving progress in oncologic and operative outcomes for esophageal and junctional cancer: lessons from the experience of a high-volume center.

LENUS (Irish Health Repository)

Reynolds, John V

2012-05-01

Modern series from high-volume esophageal centers report an approximate 40% 5-year survival in patients treated with curative intent and postoperative mortality rates of less than 4%. An objective analysis of factors that underpin current benchmarks within high-volume centers has not been performed.

Plasma uric acid and tumor volume are highly predictive of outcome in nasopharyngeal carcinoma patients receiving intensity modulated radiotherapy

International Nuclear Information System (INIS)

Lin, Hui; Lin, Huan-Xin; Ge, Nan; Wang, Hong-Zhi; Sun, Rui; Hu, Wei-Han

2013-01-01

The combined predictive value of plasma uric acid and primary tumor volume in nasopharyngeal carcinoma (NPC) patients receiving intensity modulated radiation therapy (IMRT) has not yet been determined. In this retrospective study, plasma uric acid level was measured after treatment in 130 histologically-proven NPC patients treated with IMRT. Tumor volume was calculated from treatment planning CT scans. Overall (OS), progression-free (PFS) and distant metastasis-free (DMFS) survival were compared using Kaplan-Meier analysis and the log rank test, and Cox multivariate and univariate regression models were created. Patients with a small tumor volume (<27 mL) had a significantly better DMFS, PFS and OS than patients with a large tumor volume. Patients with a high post-treatment plasma uric acid level (>301 μmol/L) had a better DMFS, PFS and OS than patients with a low post-treatment plasma uric acid level. Patients with a small tumor volume and high post-treatment plasma uric acid level had a favorable prognosis compared to patients with a large tumor volume and low post-treatment plasma uric acid level (7-year overall OS, 100% vs. 48.7%, P <0.001 and PFS, 100% vs. 69.5%, P <0.001). Post-treatment plasma uric acid level and pre-treatment tumor volume have predictive value for outcome in NPC patients receiving IMRT. NPC patients with a large tumor volume and low post-treatment plasma uric acid level may benefit from additional aggressive treatment after IMRT

Volume of hospital is important for the prognosis of high-risk patients with nonvariceal upper gastrointestinal bleeding (NVUGIB).

Science.gov (United States)

Choi, Jin Woo; Jeon, Seong Woo; Kwon, Jung Gu; Lee, Dong Wook; Ha, Chang Yoon; Cho, Kwang Bum; Jang, Byung Ik; Park, Jung Bae; Park, Youn Sun

2017-08-01

Nonvariceal upper gastrointestinal bleeding (NVUGIB) is a potentially life-threatening hospital emergency requiring hemodynamic stabilization and resuscitation. This study is carried out to determine whether hospital volume can influence outcome in patients with NVUGIB. This is a retrospective study with a prospective cohort database (KCT 0000514. cris.nih.go.kr). Eight teaching hospitals were divided into two different groups: high-volume centers (HVC, ≥60 NVUGIB patients/year, four clinics) and low-volume centers (LVC, bleeding after treatment, re-bleeding, necessity for surgical/other retreatments, and death within 30 days. Similar baseline characters for patients were observed in both groups. There was a significant difference in the incidence of poor outcome between the HVC and LVC groups (9.06 vs. 13.69%, P = 0.014). The incidence rate of poor outcome in high-risk patients (Rockall score ≥8) in HVC was lower than that in high-risk patients in LVC (16.07 vs. 26.92%, P = 0.048); however, there was no significant difference in poor outcome in the lower-risk patients in either group (8.72 vs. 10.42%, P = 0.370). Significant correlation between hospital volume and outcome in NVUGIB patients was observed. Referral to HVC for the management of high-risk NVUGIB patients should be considered in clinical practice.

Machine vision for high-precision volume measurement applied to levitated containerless material processing

International Nuclear Information System (INIS)

Bradshaw, R.C.; Schmidt, D.P.; Rogers, J.R.; Kelton, K.F.; Hyers, R.W.

2005-01-01

By combining the best practices in optical dilatometry with numerical methods, a high-speed and high-precision technique has been developed to measure the volume of levitated, containerlessly processed samples with subpixel resolution. Containerless processing provides the ability to study highly reactive materials without the possibility of contamination affecting thermophysical properties. Levitation is a common technique used to isolate a sample as it is being processed. Noncontact optical measurement of thermophysical properties is very important as traditional measuring methods cannot be used. Modern, digitally recorded images require advanced numerical routines to recover the subpixel locations of sample edges and, in turn, produce high-precision measurements

Development of a high-order finite volume method with multiblock partition techniques

Directory of Open Access Journals (Sweden)

E. M. Lemos

2012-03-01

Full Text Available This work deals with a new numerical methodology to solve the Navier-Stokes equations based on a finite volume method applied to structured meshes with co-located grids. High-order schemes used to approximate advective, diffusive and non-linear terms, connected with multiblock partition techniques, are the main contributions of this paper. Combination of these two techniques resulted in a computer code that involves high accuracy due the high-order schemes and great flexibility to generate locally refined meshes based on the multiblock approach. This computer code has been able to obtain results with higher or equal accuracy in comparison with results obtained using classical procedures, with considerably less computational effort.

High-level waste storage tank farms/242-A evaporator Standards/Requirements Identification Document (S/RID), Volume 7. Revision 1

Energy Technology Data Exchange (ETDEWEB)

Burt, D.L.

1994-04-01

The High-Level Waste Storage Tank Farms/242-A Evaporator Standards/Requirements Identification Document (S/RID) is contained in multiple volumes. This document (Volume 7) presents the standards and requirements for the following sections: Occupational Safety and Health, and Environmental Protection.

High-level waste storage tank farms/242-A evaporator Standards/Requirements Identification Document (S/RID), Volume 7. Revision 1

International Nuclear Information System (INIS)

Burt, D.L.

1994-04-01

The High-Level Waste Storage Tank Farms/242-A Evaporator Standards/Requirements Identification Document (S/RID) is contained in multiple volumes. This document (Volume 7) presents the standards and requirements for the following sections: Occupational Safety and Health, and Environmental Protection

Summer Research Program - 1998 High School Apprenticeship Program Final Reports. Volume 12, Armstrong Laboratory

National Research Council Canada - National Science Library

Moore, Gary

1998-01-01

The United States Air Force Summer Research Program (USAF-SRP) is designed to introduce university, college, and technical institute faculty members, graduate students, and high school students to Air Force research...

Summer Research Program - 1996 High School Apprenticeship Program. Volume 16, Arnold Engineering Development Center

National Research Council Canada - National Science Library

Moore, Gary

1996-01-01

The United States Air Force Summer Research Program (USAF-SRP) is designed to introduce university, college, and technical institute faculty members, graduate students, and high school students to Air Force research...

Summer Research Program - 1997 High School Appenticeship Program Volume 16 Arnold Engineering Development Center

National Research Council Canada - National Science Library

Moore, Gary

1997-01-01

The United States Air Force Summer Research Program (USAF-SRP) is designed to introduce university, college, and technical institute faculty members, graduate students, and high school students to Air Force research...

Association Between Treatment at High-Volume Facilities and Improved Overall Survival in Soft Tissue Sarcomas.

Science.gov (United States)

Venigalla, Sriram; Nead, Kevin T; Sebro, Ronnie; Guttmann, David M; Sharma, Sonam; Simone, Charles B; Levin, William P; Wilson, Robert J; Weber, Kristy L; Shabason, Jacob E

2018-03-15

Soft tissue sarcomas (STS) are rare malignancies that require complex multidisciplinary management. Therefore, facilities with high sarcoma case volume may demonstrate superior outcomes. We hypothesized that STS treatment at high-volume (HV) facilities would be associated with improved overall survival (OS). Patients aged ≥18 years with nonmetastatic STS treated with surgery and radiation therapy at a single facility from 2004 through 2013 were identified from the National Cancer Database. Facilities were dichotomized into HV and low-volume (LV) cohorts based on total case volume over the study period. OS was assessed using multivariable Cox regression with propensity score-matching. Patterns of care were assessed using multivariable logistic regression analysis. Of 9025 total patients, 1578 (17%) and 7447 (83%) were treated at HV and LV facilities, respectively. On multivariable analysis, high educational attainment, larger tumor size, higher grade, and negative surgical margins were statistically significantly associated with treatment at HV facilities; conversely, black race and non-metropolitan residence were negative predictors of treatment at HV facilities. On propensity score-matched multivariable analysis, treatment at HV facilities versus LV facilities was associated with improved OS (hazard ratio, 0.87, 95% confidence interval, 0.80-0.95; P = .001). Older age, lack of insurance, greater comorbidity, larger tumor size, higher tumor grade, and positive surgical margins were associated with statistically significantly worse OS. In this observational cohort study using the National Cancer Database, receipt of surgery and radiation therapy at HV facilities was associated with improved OS in patients with STS. Potential sociodemographic disparities limit access to care at HV facilities for certain populations. Our findings highlight the importance of receipt of care at HV facilities for patients with STS and warrant further study into improving access to

Models for high cell density bioreactors must consider biomass volume fraction: Cell recycle example.

Science.gov (United States)

Monbouquette, H G

1987-06-01

Intrinsic models, which take into account biomass volume fraction, must be formulated for adequate simulation of high-biomass-density fermentations with cell recycle. Through comparison of corresponding intrinsic and non-intrinsic models in dimensionless form, constraints for non-intrinsic model usage in terms of biokinetic and fermenter operating parameters can be identified a priori. Analysis of a simple product-inhibition model indicates that the non-intrinsic approach is suitable only when the attainable biomass volume fraction in the fermentation broth is less than about 0.10. Inappropriate application of a non-intrinsic model can lead to gross errors in calculated substrate and product concentrations, substrate conversion, and volumetric productivity.

Models for high cell density bioreactors must consider biomass volume fraction: cell recycle example

Energy Technology Data Exchange (ETDEWEB)

Monbouquette, H.G.

1987-06-01

Intrinsic models, which take into account biomass volume fraction, must be formulated for adequate simulation of high-biomass-density fermentations with cell recycle. Through comparison of corresponding intrinsic and non-intrinsic models in dimensionless form, constraints for non-intrinsic model usage in terms of biokinetic and fermenter operating parameters can be identified a priori. Analysis of a simple product-inhibition model indicates that the non-intrinsic approach is suitable only when the attainable biomass volume fraction in the fermentation broth is less than about 0.10. Inappropriate application of a non-intrinsic model can lead to gross errors in calculated substrate and product concentrations, substrate conversion, and volumetric productivity. (Refs. 14).

Operating manual for the High Flux Isotope Reactor. Volume I. Description of the facility

Energy Technology Data Exchange (ETDEWEB)

1982-09-01

This volume contains a comprehensive description of the High Flux Isotope Reactor Facility. Its primary purpose is to supplement the detailed operating procedures, providing the reactor operators with background information on the various HFIR systems. The detailed operating procdures are presented in another report.

Operating manual for the High Flux Isotope Reactor. Volume I. Description of the facility

International Nuclear Information System (INIS)

1982-09-01

This volume contains a comprehensive description of the High Flux Isotope Reactor Facility. Its primary purpose is to supplement the detailed operating procedures, providing the reactor operators with background information on the various HFIR systems. The detailed operating procdures are presented in another report

76 FR 1067 - Testing of Certain High Production Volume Chemicals; Second Group of Chemicals

Science.gov (United States)

2011-01-07

... Mfg & NOES (number based criteria based criteria significant chemicals (lbs) industrial of workers... 2070-AD16 Testing of Certain High Production Volume Chemicals; Second Group of Chemicals AGENCY... section 4(a)(1)(B) of the Toxic Substances Control Act (TSCA) to require manufacturers, importers, and...

Natural gas annual 1992. Volume 2

Energy Technology Data Exchange (ETDEWEB)

1993-11-22

This document provides information on the supply and disposition of natural gas to a wide audience including industry, consumers, Federal and State agencies, and educational institutions. This report, Volume 2, presents historical data for the Nation from 1930 to 1992, and by State from 1967 to 1992. The Supplement of this report presents profiles of selected companies.

Glass Property Data and Models for Estimating High-Level Waste Glass Volume

Energy Technology Data Exchange (ETDEWEB)

Vienna, John D.; Fluegel, Alexander; Kim, Dong-Sang; Hrma, Pavel R.

2009-10-05

This report describes recent efforts to develop glass property models that can be used to help estimate the volume of high-level waste (HLW) glass that will result from vitrification of Hanford tank waste. The compositions of acceptable and processable HLW glasses need to be optimized to minimize the waste-form volume and, hence, to save cost. A database of properties and associated compositions for simulated waste glasses was collected for developing property-composition models. This database, although not comprehensive, represents a large fraction of data on waste-glass compositions and properties that were available at the time of this report. Glass property-composition models were fit to subsets of the database for several key glass properties. These models apply to a significantly broader composition space than those previously publised. These models should be considered for interim use in calculating properties of Hanford waste glasses.

Glass Property Data and Models for Estimating High-Level Waste Glass Volume

International Nuclear Information System (INIS)

Vienna, John D.; Fluegel, Alexander; Kim, Dong-Sang; Hrma, Pavel R.

2009-01-01

This report describes recent efforts to develop glass property models that can be used to help estimate the volume of high-level waste (HLW) glass that will result from vitrification of Hanford tank waste. The compositions of acceptable and processable HLW glasses need to be optimized to minimize the waste-form volume and, hence, to save cost. A database of properties and associated compositions for simulated waste glasses was collected for developing property-composition models. This database, although not comprehensive, represents a large fraction of data on waste-glass compositions and properties that were available at the time of this report. Glass property-composition models were fit to subsets of the database for several key glass properties. These models apply to a significantly broader composition space than those previously publised. These models should be considered for interim use in calculating properties of Hanford waste glasses.

Minimization of storage and disposal volumes by treatment of liquids by highly selective ion exchangers

International Nuclear Information System (INIS)

Tusa, E.; Harjula, R.; Lehto, J.

2000-01-01

Novel highly selective inorganic ion exchangers provide new efficient methods for the treatment of nuclear waste liquids. These methods have several advantages compared to conventional technologies such as evaporation, direct solidification or treatment by organic ion exchange resins. Due to high selectivity, the radionuclides can be concentrated to a very small volume even from high-salt effluents. This means that the volume waste will be very small compared to other methods, which brings considerable savings in the cost of intermediate storage and final disposal. Process equipment are highly compact and require little supervision, which brings down the capital and operation costs. The new selective inorganic ion exchangers CsTreat, SrTreat and CoTreat (manufactured by Fortum Engineering Ltd., Finland) have the highest selectivities and processing capacities, exceeding those of zeolites by several orders of magnitude. The materials are now in use in a number of nuclear sites worldwide, including those in the USA, Europe and Japan. Installations include mobile and stationary systems. Considerable experience has been gained in the use of these new materials. Lessons learned, as well as advantages and economic benefits of these highly selective exchangers will be discussed in this paper. (authors)

Thermosetting resins with high fractions of free volume and inherently low dielectric constants.

Science.gov (United States)

Lin, Liang-Kai; Hu, Chien-Chieh; Su, Wen-Chiung; Liu, Ying-Ling

2015-08-18

This work demonstrates a new class of thermosetting resins, based on Meldrum's acid (MA) derivatives, which have high fractions of free volume and inherently low k values of about 2.0 at 1 MHz. Thermal decomposition of the MA groups evolves CO2 and acetone to create air-trapped cavities so as to reduce the dielectric constants.

Energy Research Advisory Board, Civilian Nuclear Power Panel: Subpanel 3 report, Institutional challenges: Volume IV

International Nuclear Information System (INIS)

1986-10-01

The Institutional Challenges Subpanel of the Energy Research Advisory Board's Civilian Nuclear Power Panel was charged with the task of addressing the institutional issues that affect the future of nuclear power in the United States. Barriers created by non-technical issues are generally considered to be primary obstacles to revitalizing the nuclear fission option as part of a robust supply for future electrical generation. The Subpanel examined the following categories of institutional issues: (1) Administration Policy and Leadership, (2) Licensing Reform, (3) Standardized Designs, (4) Shared Financial Risk, (5) State and Economic Regulation, (6) Waste Disposal, and (7) Public Perception. The Subpanel concluded that the Administration and Congress have the opportunity and responsibility to provide leadership in resolving these difficulties. The main report provides information on the background and current situation for each institutional issue and concludes with the set of recommendations for action

Use of the SONET Score to Evaluate High Volume Emergency Department Overcrowding: A Prospective Derivation and Validation Study

Directory of Open Access Journals (Sweden)

Hao Wang

2015-01-01

Full Text Available Background. The accuracy and utility of current Emergency Department (ED crowding estimation tools remain uncertain in EDs with high annual volumes. We aimed at deriving a more accurate tool to evaluate overcrowding in a high volume ED setting and determine the association between ED overcrowding and patient care outcomes. Methods. A novel scoring tool (SONET: Severely overcrowded-Overcrowded-Not overcrowded Estimation Tool was developed and validated in two EDs with both annual volumes exceeding 100,000. Patient care outcomes including the number of left without being seen (LWBS patients, average length of ED stay, ED 72-hour returns, and mortality were compared under the different crowding statuses. Results. The total number of ED patients, the number of mechanically ventilated patients, and patient acuity levels were independent risk factors affecting ED overcrowding. SONET was derived and found to better differentiate severely overcrowded, overcrowded, and not overcrowded statuses with similar results validated externally. In addition, SONET scores correlated with increased length of ED stay, number of LWBS patients, and ED 72-hour returns. Conclusions. SONET might be a better fit to determine high volume ED overcrowding. ED overcrowding negatively impacts patient care operations and often produces poor patient perceptions of standardized care delivery.

XV and XVI SERC Main Schools in Theoretical High Energy Physics held at the Saha Institute of Nuclear Physics and Harish-Chandra Research Institute

CERN Document Server

2005-01-01

Current research in High Energy Physics focuses on a number of enigmatic issues that go beyond the very successful Standard Model of particle physics. Among these are the problem of neutrino mass, the (as yet) unobserved Higgs particle, the quark-gluon plasma, quantum aspects of gravity, and the so--called hierarchy problem. Satisfactory resolution of these important questions will take much research effort in both theory and experiment. The Science & Engineering Research Council, Department of Science & Technology has sponsored a series of SERC Schools in Theoretical High Energy Physics over the past several years, to provide instruction and training to graduate students working for research degrees. This book is an outcome of the schools held at the Saha Institute of Nuclear Physics, Kolkata in 2000, and at the Harish-Chandra Research Institute, Allahabad in 2001. Based on lectures by active researchers in the field---Rajiv Gavai, Debashis Ghoshal, Dileep Jatkar, Anjan Joshipura, Biswarup Mukhopadhy...

High spatiotemporal resolution measurement of regional lung air volumes from 2D phase contrast x-ray images.

Science.gov (United States)

Leong, Andrew F T; Fouras, Andreas; Islam, M Sirajul; Wallace, Megan J; Hooper, Stuart B; Kitchen, Marcus J

2013-04-01

Described herein is a new technique for measuring regional lung air volumes from two-dimensional propagation-based phase contrast x-ray (PBI) images at very high spatial and temporal resolution. Phase contrast dramatically increases lung visibility and the outlined volumetric reconstruction technique quantifies dynamic changes in respiratory function. These methods can be used for assessing pulmonary disease and injury and for optimizing mechanical ventilation techniques for preterm infants using animal models. The volumetric reconstruction combines the algorithms of temporal subtraction and single image phase retrieval (SIPR) to isolate the image of the lungs from the thoracic cage in order to measure regional lung air volumes. The SIPR algorithm was used to recover the change in projected thickness of the lungs on a pixel-by-pixel basis (pixel dimensions ≈ 16.2 μm). The technique has been validated using numerical simulation and compared results of measuring regional lung air volumes with and without the use of temporal subtraction for removing the thoracic cage. To test this approach, a series of PBI images of newborn rabbit pups mechanically ventilated at different frequencies was employed. Regional lung air volumes measured from PBI images of newborn rabbit pups showed on average an improvement of at least 20% in 16% of pixels within the lungs in comparison to that measured without the use of temporal subtraction. The majority of pixels that showed an improvement was found to be in regions occupied by bone. Applying the volumetric technique to sequences of PBI images of newborn rabbit pups, it is shown that lung aeration at birth can be highly heterogeneous. This paper presents an image segmentation technique based on temporal subtraction that has successfully been used to isolate the lungs from PBI chest images, allowing the change in lung air volume to be measured over regions as small as the pixel size. Using this technique, it is possible to measure

Volume and Surface-Enhanced Volume Negative Ion Sources

International Nuclear Information System (INIS)

Stockli, M P

2013-01-01

H - volume sources and, especially, caesiated H - volume sources are important ion sources for generating high-intensity proton beams, which then in turn generate large quantities of other particles. This chapter discusses the physics and technology of the volume production and the caesium-enhanced (surface) production of H - ions. Starting with Bacal's discovery of the H - volume production, the chapter briefly recounts the development of some H - sources, which capitalized on this process to significantly increase the production of H - beams. Another significant increase was achieved in the 1990s by adding caesiated surfaces to supplement the volume-produced ions with surface-produced ions, as illustrated with other H - sources. Finally, the focus turns to some of the experience gained when such a source was successfully ramped up in H - output and in duty factor to support the generation of 1 MW proton beams for the Spallation Neutron Source. (author)

Three-dimensional reconstruction volume: a novel method for volume measurement in kidney cancer.

Science.gov (United States)

Durso, Timothy A; Carnell, Jonathan; Turk, Thomas T; Gupta, Gopal N

2014-06-01

The role of volumetric estimation is becoming increasingly important in the staging, management, and prognostication of benign and cancerous conditions of the kidney. We evaluated the use of three-dimensional reconstruction volume (3DV) in determining renal parenchymal volumes (RPV) and renal tumor volumes (RTV). We compared 3DV with the currently available methods of volume assessment and determined its interuser reliability. RPV and RTV were assessed in 28 patients who underwent robot-assisted laparoscopic partial nephrectomy for kidney cancer. Patients with a preoperative creatinine level of kidney pre- and postsurgery overestimated 3D reconstruction volumes by 15% to 102% and 12% to 101%, respectively. In addition, volumes obtained from 3DV displayed high interuser reliability regardless of experience. 3DV provides a highly reliable way of assessing kidney volumes. Given that 3DV takes into account visible anatomy, the differences observed using previously published methods can be attributed to the failure of geometry to accurately approximate kidney or tumor shape. 3DV provides a more accurate, reproducible, and clinically useful tool for urologists looking to improve patient care using analysis related to volume.

Institute of Bioinorganic and Radiopharmaceutical Chemistry. Annual report 1992

International Nuclear Information System (INIS)

Johannsen, B.

1993-04-01

The Institute of Bioinorganic and Radiopharmaceutical Chemistry of the Rossendorf Research Center (FZR) presents its 1992 anual report in order to in form on research activities in the first year of its existence. This volume contains 27 individual reports devoted to various aspects of radiotracers for nuclear medicine. (BBR)

PIEZOELECTRIC WAVEGUIDE SENSOR FOR MEASURING PULSE PRESSURE IN CLOSED LIQUID VOLUMES AT HIGH VOLTAGE ELECTRIC DISCHARGE

Directory of Open Access Journals (Sweden)

V. G. Zhekul

2017-10-01

Full Text Available Purpose. Investigations of the characteristics of pressure waves presuppose the registration of the total profile of the pressure wave at a given point in space. For these purposes, various types of «pressure to the electrical signal» transmitters (sensors are used. Most of the common sensors are unsuitable for measuring the pulse pressure in a closed water volume at high hydrostatic pressures, in particular to study the effect of a powerful high-voltage pulse discharge on increasing the inflow of minerals and drinking water in wells. The purpose of the work was to develop antijamming piezoelectric waveguide sensor for measuring pulse pressure at a close distance from a high-voltage discharge channel in a closed volume of a liquid. Methodology. We have applied the calibration method as used as a secondary standard, the theory of electrical circuits. Results. We have selected the design and the circuit solution of the waveguide pressure sensor. We have developed a waveguide pulse-pressure sensor DTX-1 with a measuring loop. This sensor makes it possible to study the spectral characteristics of pressure waves of high-voltage pulse discharge in closed volumes of liquid at a hydrostatic pressure of up to 20 MPa and a temperature of up to 80 °C. The sensor can be used to study pressure waves with a maximum amplitude value of up to 150 MPa and duration of up to 80 µs. According to the results of the calibration, the sensitivity of the developed sensor DTX-1 with a measuring loop is 0.0346 V/MPa. Originality. We have further developed the theory of designing the waveguide piezoelectric pulse pressure sensors for measuring the pulse pressure at a close distance from a high-voltage discharge channel in a closed fluid volume by controlling the attenuation of the amplitude of the pressure signal. Practical value. We have developed, created, calibrated, used in scientific research waveguide pressure pulse sensors DTX-1. We propose sensors DTX-1 for sale

High lung cancer surgical procedure volume is associated with shorter length of stay and lower risks of re-admission and death

DEFF Research Database (Denmark)

Møller, Henrik; Riaz, Sharma P; Holmberg, Lars

2016-01-01

It is debated whether treating cancer patients in high-volume surgical centres can lead to improvement in outcomes, such as shorter length of hospital stay, decreased frequency and severity of post-operative complications, decreased re-admission, and decreased mortality. The dataset for this anal......It is debated whether treating cancer patients in high-volume surgical centres can lead to improvement in outcomes, such as shorter length of hospital stay, decreased frequency and severity of post-operative complications, decreased re-admission, and decreased mortality. The dataset...... to their geographical population. Higher volume hospitals had shorter length of stay and the odds of re-admission were 15% lower in the highest hospital volume quintile compared with the lowest quintile. Mortality risks were 1% after 30 d and 3% after 90 d. Patients from hospitals in the highest volume quintile had...

Enlarged Halden programme group meeting on high burn-up fuel performance, safety and reliability and degradation of in-core materials and water chemistry effects and man-machine systems research. Volume II

International Nuclear Information System (INIS)

1999-01-01

Academy of Sciences, KFKI Atomic Energy Research Institute, the N.V. KEMA, the Netherlands, the Russian Research Centre 'Kurchatov Institute', the Slovakian VUJE - Nuclear Power Plant Research Institute, and from USA: the ABB Combustion Engineering Inc., the Electric Power Research Institute (EPRI), and the General Electric Co. The right to utilise information originating from the research work of the Halden Project is limited to persons and undertakings specifically given this right by one of these Project member organisations. The activities in the area of fuel and materials performance are based on extensive in-reactor measurements. The programmes are expanding in the areas of fuel performance at extended burn-ups, waterside corrosion and material testing in general. Development of in-core instruments is an important activity in support of the experimental programmes. The research programme at the Halden Project addresses the research needs of the nuclear industry in connection with introduction of digital I and C systems in NPPs. The programme provides information supporting design and licensing of upgraded, computer-based control room systems, and demonstrates the benefits of such systems through validation experiments in Halden's experimental research facility, HAMMLAB and pilot installations in NPPs. The Enlarged Halden Programme Group Meeting at Loen, Norway, was arranged to provide an opportunity to present results of work carried out at Halden and within participating organisations, and to encourage comments and impulses related to future Halden Project work. This HPR-351 relates to the fuel and materials part of the meeting and is divided in two volumes, HPR-351 Volume I and HPR-351 Volume II. The corresponding collection of papers in the man-machine area are given in one volume, HPR-352 Volume I. The overall programme of the Loen Enlarged Meeting covering the Fuel and Materials Research is given in the following pages. The papers with denomination HWR have

Survival in pediatric lung transplantation: The effect of center volume and expertise.

Science.gov (United States)

Khan, Muhammad S; Zhang, Wei; Taylor, Rachel A; Dean McKenzie, E; Mallory, George B; Schecter, Marc G; Morales, David L S; Heinle, Jeffrey S; Adachi, Iki

2015-08-01

Institutional operative volume has been shown to impact outcomes of various procedures including lung transplantation (LTx). We sought to determine whether this holds true with pediatric LTx by comparing outcomes of adult centers (with larger overall volume) to those of pediatric centers (with smaller volume but more pediatric-specific experience). A retrospective analysis of the Organ Procurement and Transplant Network data was performed. Centers were categorized as either adult (LTx volume predominantly in adult patients), high-volume pediatric (HVP, ≥4 LTxs/year), or low-volume pediatric (LVP, HVP 3 [5%], LVP 8 [13%]). Although adult centers had larger overall LTx volume, their pediatric experiences were severely limited (median 1/year). In younger children, HVP centers were significantly better than LVP centers for patient survival (half-life: 7.3 vs 2.9 years, p = 0.002). Similarly, in older children and adolescents, HVP centers were significantly better than adult centers for patient survival (half-life: 4.6 vs 2.5 years, p = 0.001). Of note, even LVP centers tended to have longer patient survival than adult centers (p = 0.064). Multivariable analysis identified adult centers as an independent risk factor for graft failure (hazard ratio: 1.5, p < 0.001) as with LVP (hazard ratio: 1.3, p = 0.0078). Despite larger overall clinical volume, outcomes among pediatric LTx recipients in adult centers are not superior to those of pediatric centers. Not only center volume but pediatric-specific experience has an impact on outcomes in pediatric LTx. Copyright © 2015 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.

Pediatric blood volumes: a one-page reference guide.

Science.gov (United States)

Smiley, J; Reitan, J

1998-10-01

At our institution, a multidisciplinary team met to work out a blood volume policy for our pediatric patients' laboratory testing. Because we are a cancer center, many of our patients are on protocols and/or are in the hospital for an extended period of time. These factors result in multiple blood draws. It is important to manage the volumes used so that we do not compromise the hematological status of our pediatric patients. The concerns of nurses and laboratory technologists were discussed and a three-tiered system was designed consisting of adult volumes, volumes for inflexibility to verify or add to the original order without resticking the patient increase at each tier. It is imperative to the overall quality of care for all patients that discretion is used when following these guidelines. When it is medically prudent to restrict the blood volumes taken from any patient, it should be done. However, when it is not medically necessary, the increased costs and potential decrease in the quality of laboratory service outweighs the desire to use smaller blood volumes.

High Power Microwave Tubes: Basics and Trends, Volume 2

Science.gov (United States)

Kesari, Vishal; Basu, B. N.

2018-01-01

Volume 2 of the book begins with chapter 6, in which we have taken up conventional MWTs (such as TWTs, klystrons, including multi-cavity and multi-beam klystrons, klystron variants including reflex klystron, IOT, EIK, EIO and twystron, and crossed-field tubes, namely, magnetron, CFA and carcinotron). In chapter 7, we have taken up fast-wave tubes (such as gyrotron, gyro-BWO, gyro-klystron, gyro-TWT, CARM, SWCA, hybrid gyro-tubes and peniotron). In chapter 8, we discuss vacuum microelectronic tubes (such as klystrino module, THz gyrotron and clinotron BWO); plasma-assisted tubes (such as PWT, plasma-filled TWT, BWO, including PASOTRON, and gyrotron); and HPM (high power microwave) tubes (such as relativistic TWT, relativistic BWO, RELTRON (variant of relativistic klystron), relativistic magnetron, high power Cerenkov tubes including SWO, RDG or orotron, MWCG and MWDG, bremsstrahlung radiation type tube, namely, vircator, and M-type tube MILO). In Chapter 9, we provide handy information about the frequency and power ranges of common MWTs, although more such information is provided at relevant places in the rest of the book as and where necessary. Chapter 10 is an epilogue that sums up the authors' attempt to bring out the various aspects of the basics of and trends in high power MWTs.

Effects of Physician Volume on Readmission and Mortality in Elderly Patients with Heart Failure: Nationwide Cohort Study.

Science.gov (United States)

Lee, Joo Eun; Park, Eun Cheol; Jang, Suk Yong; Lee, Sang Ah; Choy, Yoon Soo; Kim, Tae Hyun

2018-03-01

Readmission and mortality rates of patients with heart failure are good indicators of care quality. To determine whether hospital resources are associated with care quality for cardiac patients, we analyzed the effect of number of physicians and the combined effects of number of physicians and beds on 30-day readmission and 1-year mortality. We used national cohort sample data of the National Health Insurance Service (NHIS) claims in 2002-2013. Subjects comprised 2345 inpatients (age: >65 years) admitted to acute-care hospitals for heart failure. A multivariate Cox regression was used. Of the 2345 patients hospitalized with heart failure, 812 inpatients (34.6%) were readmitted within 30 days and 190 (8.1%) had died within a year. Heart-failure patients treated at hospitals with low physician volumes had higher readmission and mortality rates than high physician volumes [30-day readmission: hazard ratio (HR)=1.291, 95% confidence interval (CI)=1.020-1.633; 1-year mortality: HR=2.168, 95% CI=1.415-3.321]. Patients admitted to hospitals with low or middle bed and physician volume had higher 30-day readmission and 1-year mortality rates than those admitted to hospitals with high volume (30-day readmission: HR=2.812, 95% CI=1.561-5.066 for middle-volume beds & low-volume physicians, 1-year mortality: HR=8.638, 95% CI=2.072-36.02 for middle-volume beds & low-volume physicians). Physician volume is related to lower readmission and mortality for heart failure. Of interest, 30-day readmission and 1-year mortality were significantly associated with the combined effects of physician and institution bed volume. © Copyright: Yonsei University College of Medicine 2018

Development of Small-Volume, High-Precision, and Reliable Cryogenic Linear Actuators by Using Novel Intermetallic Compounds

Data.gov (United States)

National Aeronautics and Space Administration — Space missions often involve ultra-cold environments, and cryogenic actuators must be mechanically robust for long-term cyclic work, generate high power per volume,...

A high volume, batch mode {sup 129}Xe polarizer

Energy Technology Data Exchange (ETDEWEB)

Wojna-Pelczar, Anna, E-mail: anna.wojna.pelczar@mail.muni.cz [Central European Institute of Technology, Masaryk University, Brno (Czech Republic); Formerly: Marian Smoluchowski Institute of Physics, Jagiellonian University, Kraków (Poland); Pałasz, Tadeusz [Marian Smoluchowski Institute of Physics, Jagiellonian University, Kraków (Poland)

2017-06-01

Numerous designs of optical gas polarizers have been proposed, broadening possible applications of the hyperpolarized gases as contrast agents in magnetic resonance imaging. We present a home–made {sup 129}Xe polarizer based on the spin exchange optical pumping method. The polarizer operates under 1 bar of the gas mixture (at the maximum temperature of 160 °C) in a high volume optical cell (5025 cm{sup 3}). Approximately 100 cm{sup 3} of {sup 129}Xe polarized at 1.50±0.37% is produced in a single cycle of polarization. Operation under standard pressure imposes polarization transfer mainly via van der Waals molecules, resulting in the efficient spin exchange between rubidium and {sup 129}Xe atoms. The design, construction and operation of the polarizer are described in details.

Effect of uncertainty in pore volumes on the uncertainty in amount adsorbed at high-pressures on activated carbon cloth

International Nuclear Information System (INIS)

Pendleton, Ph.; Badalyan, A.

2005-01-01

Activated carbon cloth (ACC) is a good adsorbent for high rate adsorption of volatile organic carbons [1] and as a storage media for methane [2]. It has been shown [2] that the capacity of ACC to adsorb methane, in the first instance, depends on its micropore volume. One way of increasing this storage capacity is to increase micropore volume [3]. Therefore, the uncertainty in the determination of ACC micropore volume becomes a very important factor, since it affects the uncertainty of amount adsorbed at high-pressures, which usually accompany storage of methane on ACC. Recently, we developed a method for the calculation of experimental uncertainty in micropore volume using low pressure nitrogen adsorption data at 77 K for FM1/250 ACC (ex. Calgon, USA). We tested several cubic equations of state (EOS) and multiple parameter (EOS) to determine the amount of high-pressure nitrogen adsorbed, and compared these data with amounts calculated via interpolated NIST density data. The amount adsorbed calculated from interpolated NIST density data exhibit the lowest propagated combined uncertainty. Values of relative combined standard uncertainty for FM1/250 calculated using a weighted, mean-least-squares method applied to the low-pressure nitrogen adsorption data (Fig. 1) gave 3.52% for the primary micropore volume and 1.63% for the total micropore volume. Our equipment allows the same sample to be exposed to nitrogen (and other gases) at pressures from 10 -4 Pa to 17-MPa in the temperature range from 176 to 252 K. The maximum uptake of nitrogen was 356-mmol/g at 201.92 K and 15.8-MPa (Fig. 2). The delivery capacity of ACC is determined by the amount of adsorbed gas recovered when the pressure is reduced from that for maximum adsorption to 0.1-MPa [2]. In this regard, the total micropore volume becomes an important parameter in determining the amount of gas delivered during desorption. In the present paper we will discuss the effect of uncertainty in micropore volume

A high volume cost efficient production macrostructuring process. [for silicon solar cell surface treatment

Science.gov (United States)

Chitre, S. R.

1978-01-01

The paper presents an experimentally developed surface macro-structuring process suitable for high volume production of silicon solar cells. The process lends itself easily to automation for high throughput to meet low-cost solar array goals. The tetrahedron structure observed is 0.5 - 12 micron high. The surface has minimal pitting with virtually no or very few undeveloped areas across the surface. This process has been developed for (100) oriented as cut silicon. Chemi-etched, hydrophobic and lapped surfaces were successfully texturized. A cost analysis as per Samics is presented.

Paul Scherrer Institute Scientific Report 2000. Volume III: Condensed Matter Research with Neutrons

Energy Technology Data Exchange (ETDEWEB)

Schefer, Juerg; Castellazzi, Denise; Shea-Braun, Margit [eds.

2001-07-01

This year started with a highlight for the Swiss Spallation Neutron Source SINQ located at PSI: The thermal neutron flux exceeded the value of 10{sup 14} n cm{sup -2} s{sup 1} which may be considered as the critical limit for an advanced medium-flux neutron source. The excellent performance attracted a large number of external users to participate at the neutron scattering programme. The major part of this annual report gives an overview on the scientific activities of the staff members of the Laboratory of Neutron Scattering (jointly operated with the Swiss Federal Institute of Technology, ETH Zurich). The research topics covered diverse areas such as strongly correlated electron systems including high-temperature superconductors, low-dimensional and quantum magnetism, materials research on soft and hard matter including multilayers. Progress in 2000 in these topical areas as well as the activities of the Condensed Matter Theory Group, and the Group for Low Temperature Facilities, is described in this report. A list of scientific publications in 2000 is also provided.

Paul Scherrer Institute Scientific Report 1999. Volume III: Condensed Matter Research with Neutrons

Energy Technology Data Exchange (ETDEWEB)

Schefer, Juerg; Castellazzi, Denise; Shea-Braun, Margit [eds.

2000-07-01

This year was a period of consolidation of the operation at the spallation source of PSI and its scientific exploitation at an increasing number of instruments. The major part of this annual report gives an overview of the research activities in the Laboratory of Neutron Scattering (jointly operated with the Swiss Federal Institute of Technology, ETH Zurich) of our department, mainly emphasizing highly correlated electron systems and the investigation of magnetism. The activities on multilayers and surfaces, a basic research object by itself, is however also to a large extent motivated by the development of optical components for neutron- and X-ray instrumentation. While most of the solid-state work has been done with neutrons, some contributions deal with other probes, like muons and synchrotron light, exploiting the unique possibilities at PSI, to take advantage of the complementary nature of the different probes. Progress in 1999 in these topical areas as well as the activities of the Condensed Matter Theory Group, and the Group for Low Temperature Facilities, is described in this report. A list of scientific publications in 1999 is also provided.

Paul Scherrer Institute Scientific Report 2000. Volume III: Condensed Matter Research with Neutrons

International Nuclear Information System (INIS)

Schefer, Juerg; Castellazzi, Denise; Shea-Braun, Margit

2001-01-01

This year started with a highlight for the Swiss Spallation Neutron Source SINQ located at PSI: The thermal neutron flux exceeded the value of 10 14 n cm -2 s 1 which may be considered as the critical limit for an advanced medium-flux neutron source. The excellent performance attracted a large number of external users to participate at the neutron scattering programme. The major part of this annual report gives an overview on the scientific activities of the staff members of the Laboratory of Neutron Scattering (jointly operated with the Swiss Federal Institute of Technology, ETH Zurich). The research topics covered diverse areas such as strongly correlated electron systems including high-temperature superconductors, low-dimensional and quantum magnetism, materials research on soft and hard matter including multilayers. Progress in 2000 in these topical areas as well as the activities of the Condensed Matter Theory Group, and the Group for Low Temperature Facilities, is described in this report. A list of scientific publications in 2000 is also provided

Paul Scherrer Institute Scientific Report 1999. Volume III: Condensed Matter Research with Neutrons

International Nuclear Information System (INIS)

Schefer, Juerg; Castellazzi, Denise; Shea-Braun, Margit

2000-01-01

This year was a period of consolidation of the operation at the spallation source of PSI and its scientific exploitation at an increasing number of instruments. The major part of this annual report gives an overview of the research activities in the Laboratory of Neutron Scattering (jointly operated with the Swiss Federal Institute of Technology, ETH Zurich) of our department, mainly emphasizing highly correlated electron systems and the investigation of magnetism. The activities on multilayers and surfaces, a basic research object by itself, is however also to a large extent motivated by the development of optical components for neutron- and X-ray instrumentation. While most of the solid-state work has been done with neutrons, some contributions deal with other probes, like muons and synchrotron light, exploiting the unique possibilities at PSI, to take advantage of the complementary nature of the different probes. Progress in 1999 in these topical areas as well as the activities of the Condensed Matter Theory Group, and the Group for Low Temperature Facilities, is described in this report. A list of scientific publications in 1999 is also provided

Nuclear legislation analytical study. Regulatory and institutional framework for nuclear activities in OECD member countries. Volume II

International Nuclear Information System (INIS)

1984-01-01

This study is part of a series of analytical studies of the major aspects of nuclear legislation in OECD Member countries and is published in two volumes. This volume II of the study is a revision and an expansion of a 1969 study concerning the organisation and general regime governing nuclear activities. The national studies were prepared, to the extent possible, following a standard plan for all countries to facilitate information retrieval and comparison. This volume also contains tables of international conventions of relevance to the nuclear field. (NEA) [fr

2nd Anniversary Symposium of the Institute of Mathematical Sciences Madras, India

CERN Document Server

1995-01-01

The second volume of this series is devoted to the Proceedings of the Second Anniversary Symposium under the chairmanship of the Niels Bohr Visiting Professor of the year - Professor L. Rosenfeld, Deputy Director of NORDIT A, Copenhagen, and the Editor of Nuclear Physics. With particular appropriateness, the Symposium was inaugu­ rated by the Honorable C. Subramaniam, Union Cabinet Minister, the founding father of the Institute. The meeting was characterized by two features: (1) the enlargement of the scope of the discussions in theoretical physics, with the inclusion of many-body problems and statistical mechanics! (2) Seminars on pure mathematics, stimulated by the prdence and participation of Professor Marshall H. Stone of Chicago as the First Ramanujan Visit­ ing Professor at the Institute. The year 1963 marked a new stage in the development of high­ energy physics - the first successes of SU (3) symmetry and the eight­ fold way had such an impact on the scientific world that the hard, unyielding doma...

Dual Enrollment Programs and Courses for High School Students at Postsecondary Institutions: 2010-11. First Look. NCES 2013-002

Science.gov (United States)

Marken, Stephanie; Gray, Lucinda; Lewis, Laurie

2013-01-01

This report provides descriptive national data on the prevalence and characteristics of dual enrollment programs at postsecondary institutions in the United States. For this survey, dual enrollment refers to high school students earning college credits for courses taken through a postsecondary institution. The National Center for Education…

Paul Scherrer Institute Scientific Report 1999. Volume II: Life Sciences

Energy Technology Data Exchange (ETDEWEB)

Jaussi, Rolf; Gschwend, Beatrice [eds.

2000-07-01

The existing activities of the Department of Life Sciences have grown out of the specific know how and the unique experimental possibilities available at PSI. Primarily, these have been and are complex facilities for using particle beams (protons, neutrons) on the one hand and know how in the production, handling and chemistry of radionuclides on the other. The common theme of the department has thus been the study and use of various types of radiation in therapy and diagnostics of human disease and in particular of cancer. The four units active in this area are: The major activity in the Radiation Medicine unit is Proton Therapy, which aims to further develop and optimise the world-wide unique spot scanning facility for irradiating malignant tumours with minimal damage to surrounding healthy tissues, including the established OPTIS program for the treatment of eye tumours. The Centre for Radiopharmaceutical Science represents a joint activity of PSI with the Swiss Federal Institute of Technology (ETHZ) and the University of Zurich. Its major goals are the development of novel tumour targeted radioconjugates for cancer diagnosis and therapy and the production and evaluation of new PET (positron emission tomography) radiotracers for various applications in neuro physiology and drug development. The Institute of Medical Radiobiology analyses questions of the molecular biology of DNA repair. It is a joint activity of PSI and the University of Zurich. The Structural Biology unit is currently being established. A strong in-house research activity in macromolecular crystallography will complement the more user-oriented protein crystallography beam line, which is being built at the Swiss Light Source (SLS). In particular, tumour targeting by molecular vehicles and DNA repair are areas where structural information can provide important insights. Progress in 1999 in these topical areas is described in this report. A list of scientific publications in 1999 is also provided.

Paul Scherrer Institute Scientific Report 1999. Volume II: Life Sciences

International Nuclear Information System (INIS)

Jaussi, Rolf; Gschwend, Beatrice

2000-01-01

The existing activities of the Department of Life Sciences have grown out of the specific know how and the unique experimental possibilities available at PSI. Primarily, these have been and are complex facilities for using particle beams (protons, neutrons) on the one hand and know how in the production, handling and chemistry of radionuclides on the other. The common theme of the department has thus been the study and use of various types of radiation in therapy and diagnostics of human disease and in particular of cancer. The four units active in this area are: The major activity in the Radiation Medicine unit is Proton Therapy, which aims to further develop and optimise the world-wide unique spot scanning facility for irradiating malignant tumours with minimal damage to surrounding healthy tissues, including the established OPTIS program for the treatment of eye tumours. The Centre for Radiopharmaceutical Science represents a joint activity of PSI with the Swiss Federal Institute of Technology (ETHZ) and the University of Zurich. Its major goals are the development of novel tumour targeted radioconjugates for cancer diagnosis and therapy and the production and evaluation of new PET (positron emission tomography) radiotracers for various applications in neuro physiology and drug development. The Institute of Medical Radiobiology analyses questions of the molecular biology of DNA repair. It is a joint activity of PSI and the University of Zurich. The Structural Biology unit is currently being established. A strong in-house research activity in macromolecular crystallography will complement the more user-oriented protein crystallography beam line, which is being built at the Swiss Light Source (SLS). In particular, tumour targeting by molecular vehicles and DNA repair are areas where structural information can provide important insights. Progress in 1999 in these topical areas is described in this report. A list of scientific publications in 1999 is also provided

Strategic planning in a highly specialized orthopaedic institution

Directory of Open Access Journals (Sweden)

Vukašinović Zoran

2009-01-01

Full Text Available Introduction. The Institute for Orthopaedic Surgery 'Banjica' in Belgrade provides tertiary healthcare services on national level. After decades of constant development, a recent decline coincided with the decade of great social and governmental disturbance, the transition period after the dissociation of former Yugoslavia. Objective. In order to overcome the crisis, we used modern management methods to define problems in the institution management, and to propose appropriate strategies. Methods. A survey that included 100 employees (17.67% was carried out, followed by descriptive statistical analysis, PEST and SWOT analyses. Results The impact of political fluctuations, ageing of population, financing model, obsolete medical technology was evaluated. Various personal and interpersonal factors were assessed: the quality of medical service (3.59±0.76, mark 1-5; relations among health service participants (3.39±0.78; occupational conditions (not good-91%; human, financial and other resources; professional cooperation, stimulation; rivalry and mobbing (declared in 56%; public informing, institution image (rank 3.70±0.88 and PR activities (new to 78%. 93% declared to give maximum effort at work. Conclusion. Using these results, we defined several strategic objectives. These include strengthening scientific activities, general orientation to specific and exclusive pathological conditions and treatment methods, improvement of management transparency, introduction of quality-based stimulation of workers, support of promotional and PR activities.

Institutional Review Boards at Very High Research Activity Universities: An Opportunity for Social Workers

Science.gov (United States)

Cannon, Clare; Buttell, Frederick

2015-01-01

Objectives: This study investigated to what degree social work was represented in the position of chair of social-behavioral institutional review boards (IRBs) at very high research activity (VHRA) universities in the United States. Method: We collected data on IRB rosters for all 108 schools designated by the Carnegie Foundation as VHRAs in the…

Nuclear carrier business volume projections, 1980-2000

International Nuclear Information System (INIS)

Lebo, R.G.; McKeown, M.S.; Rhyne, W.R.

1980-05-01

The expected number of shipments of commodities in the nuclear fuel cycle are projected for the years 1980 thru 2000. Projections are made for: yellowcake (U 3 O 8 ); natural, enriched and reprocessed uranium hexafluoride (UF 6 ); uranium dioxide powder (UO 2 ); plutonium dioxide powder (PuO 2 ); fresh UO 2 and mixed oxide (MOX) fuel; spent UO 2 fuel; low-level waste (LLW); transuranic (TRU) waste; high-activity TRU waste; high-level waste (HLW), and cladding hulls. Projections are also made for non-fuel cycle commodities such as defense TRU wastes and institutional wastes, since they also are shipped by the commercial transportation industry. Projections of waste shipments from LWRs are based on the continuation of current volume reduction and solidification techniques now used by the utility industry. Projections are also made based on a 5% per year reduction in LWR waste volume shipped which is assumed to occur as a result of increased implementation of currently available volume reduction systems. This assumption results in a net 64% decrease in the total waste shipped by the year 2000. LWR waste shipment projections, and essentially all other projections for fuel cycle commodities covered in this report, are normalized to BWR and PWR generating capacity projections set forth by the Department of Energy (DOE) in their low-growth projection of April, 1979. Therefore these commodity shipment projections may be altered to comply with future changes in generating capacity projections. Projected shipments of waste from the reprocessing of spent UO 2 fuel are based on waste generation rates proposed by Nuclear Fuels Services, Allied-General Nuclear Services, Exxon Nuclear, and the DOE. Reprocessing is assumed to begin again in 1990, with mixed oxide fresh fuel available for shipment by 1991

Nigeria : Financial Sector Review, Volume 3. Non-Bank Financial Institutions and Markets

OpenAIRE

World Bank

2000-01-01

This report is a comprehensive review of the Nigerian financial system, covering the following areas: i) macro-financial environment; ii) safety and soundness of the banking system; iii) banking supervision; iv) development finance institutions; v) community banks and commercial banks' rural operations; vi) insurance and pensions; vii) housing finance; viii) money and capital markets; and ...

The institutional arrangements of innovation: Antecedents and performance effects of trust in high-tech alliances

NARCIS (Netherlands)

Jong, G.; Klein Woolthuis, R.J.A.

2008-01-01

In this study we investigate the institutional arrangements of innovation processes in high-tech alliances, focusing on the role of trust. A major strength of the research is the opportunity to address antecedents as well as performance effects of trust. The antecedents of interorganizational trust

Damping behavior of polymer composites with high volume fraction of NiMnGa powders

Science.gov (United States)

Sun, Xiaogang; Song, Jie; Jiang, Hong; Zhang, Xiaoning; Xie, Chaoying

2011-03-01

Polymer composites inserted with high volume fraction (up to 70 Vol%) of NiMnGa powders were fabricated and their damping behavior was investigated by dynamic mechanical analysis. It is found that the polymer matrix has little influence on the transformation temperatures of NiMnGa powders. A damping peak appears for NiMnGa/epoxy resin (EP) composites accompanying with the martensitic transformation or reverse martensitic transformation of NiMnGa powders during cooling or heating. The damping capacity for NiMnGa/EP composites increases linearly with the increase of volume fraction of NiMnGa powders and, decreases dramatically as the test frequency increases. The fracture strain of NiMnGa/EP composites decrease with the increase of NiMnGa powders.

Summer Research Program - 1997. High School Apprenticeship Program. Final Reports, Volume 12A, Armstrong Laboratory

National Research Council Canada - National Science Library

Moore, Gary

1997-01-01

The United States Air Force Summer Research Program (USAF-SRP) is designed to introduce university, college, and technical institute faculty members, graduate students, and high school students to Air Force research...

Summer Research Program - 1997. High School Apprenticeship Program. Final Reports Volume 15B, Wright Laboratory

National Research Council Canada - National Science Library

Moore, Gary

1997-01-01

The United States Air Force Summer Research Program (USAF-SRP) is designed to introduce university, college, and technical institute faculty members, graduate students, and high school students to Air Force research...

Summer Research Program - 1996. High School Apprenticeship Program Final Reports. Volume 15B, Wright Laboratory

National Research Council Canada - National Science Library

Moore, Gary

1996-01-01

The United States Air Force Summer Research Program (USAF-SRP) is designed to introduce university, college, and technical institute faculty members, graduate students, and high school students to Air Force research...

Summer Research Program - 1997. High School Apprenticeship Program Final Reports. Volume 15A, Wright Laboratory

National Research Council Canada - National Science Library

Moore, Gary

1997-01-01

The United States Air Force Summer Research Program (USAF-SRP) is designed to introduce university, college, and technical institute faculty members, graduate students, and high school students to Air Force research...

Summer Research Program - 1997. High School Apprenticeship Program. Final Reports. Volume 15C, Wright Laboratory

National Research Council Canada - National Science Library

Moore, Gary

1997-01-01

The United States Air Force Summer Research Program (USAF-SRP) is designed to introduce university, college, and technical institute faculty members, graduate students, and high school students to Air Force research...

Integral dose and evaluation of irradiated tissue volume

International Nuclear Information System (INIS)

Sivachenko, T.P.; Kalina, V.K.; Belous, A.K.; Gaevskij, V.I.

1984-01-01

Two parameters having potentialities of radiotherapy planning improvement are under consideration. One of these two parameters in an integral dose. An efficiency of application of special tables for integral dose estimation is noted. These tables were developed by the Kiev Physician Improvement Institute and the Cybernetics Institute of the Ukrainian SSR Academy of Science. The meaning of the term of ''irradiated tissue volume'' is specified, and the method of calculation of the irradiated tissue effective mass is considered. It is possible to evaluate with higher accuracy tolerance doses taking into account the irradiated mass

Information and Communication Technologies in Africa Volume 1 ...

International Development Research Centre (IDRC) Digital Library (Canada)

Volume 1 looks at the introduction, adoption, and utilization of ICTs at the community level. In various contexts – geographical, technological, socioeconomic, cultural, and institutional – the book explores the questions of community participation. It looks at how communities in sub-Saharan Africa have reacted to the changes ...

Development of Automatic Visceral Fat Volume Calculation Software for CT Volume Data

Directory of Open Access Journals (Sweden)

Mitsutaka Nemoto

2014-01-01

Full Text Available Objective. To develop automatic visceral fat volume calculation software for computed tomography (CT volume data and to evaluate its feasibility. Methods. A total of 24 sets of whole-body CT volume data and anthropometric measurements were obtained, with three sets for each of four BMI categories (under 20, 20 to 25, 25 to 30, and over 30 in both sexes. True visceral fat volumes were defined on the basis of manual segmentation of the whole-body CT volume data by an experienced radiologist. Software to automatically calculate visceral fat volumes was developed using a region segmentation technique based on morphological analysis with CT value threshold. Automatically calculated visceral fat volumes were evaluated in terms of the correlation coefficient with the true volumes and the error relative to the true volume. Results. Automatic visceral fat volume calculation results of all 24 data sets were obtained successfully and the average calculation time was 252.7 seconds/case. The correlation coefficients between the true visceral fat volume and the automatically calculated visceral fat volume were over 0.999. Conclusions. The newly developed software is feasible for calculating visceral fat volumes in a reasonable time and was proved to have high accuracy.

High-volume infiltration analgesia in total knee arthroplasty: a randomized, double-blind, placebo-controlled trial

DEFF Research Database (Denmark)

Andersen, L.O.; Husted, H.; Otte, K.S.

2008-01-01

with a detailed description of the infiltration technique. METHODS: In a randomized, double-blind, placebo-controlled trial in 12 patients undergoing bilateral knee arthroplasty, saline or high-volume (170 ml) ropivacaine (0.2%) with epinephrine was infiltrated around each knee, with repeated doses administered...

A lean production control system for high-variety/low-volume environments : a case study implementation

NARCIS (Netherlands)

Slomp, J.; Bokhorst, J.A.C.; Germs, R.

2009-01-01

Due to the success of lean manufacturing, many companies are interested in implementing a lean production control system. Lean production control principles include the levelling of production, the use of pull mechanisms and takt time control. These principles have mainly been applied in high volume

The study of multi-institutional collaborations in high-energy physics. Progress report, January 1989--March 1991

Energy Technology Data Exchange (ETDEWEB)

1991-12-31

Since World War II, the organizational framework for scientific research is increasingly the multi-institutional collaboration, especially in high-energy physics. A broad preliminary survey, into the functioning of research collaborations involving three or more institutions is described. The study is designed to identify patterns of collaborations, define the scope of the documentation problems, field-test possible solutions, recommend future actions, and build an archives of oral history interviews and other resources for scholarly use. Once the study is completed, its findings will be used to promote systems to document significant collaborative research.

Industrial based volume manufacturing of lightweight aluminium alloy panel components with high-strength and complex-shape for car body and chassis structures

Science.gov (United States)

Anyasodor, Gerald; Koroschetz, Christian

2017-09-01

To achieve the high volume manufacture of lightweight passenger cars at economic cost as required in the automotive industry, low density materials and new process route will be needed. While high strength aluminium alloy grades: AA7075 and AA6082 may provide the alternative material solution, hot stamping process used for high-strength and ultrahigh strength steels such as boron steel 22mnb5 can enable the volume manufacture of panel components with high-strength and complex-shape for car body and chassis structures. These aluminium alloy grades can be used to manufacture panel components with possible yield strengths ≥ 500 MPa. Due to the differences in material behaviors, hot stamping process of 22mnb5 cannot be directly applied to high strength aluminium alloy grades. Despite recorded successes in laboratories, researches and niche hot forming processes of high strength aluminium alloy grades, not much have been achieved for adequate and efficient volume manufacturing system applicable in the automotive industry. Due to lack of such system and based on expert knowledge in hot stamping production-line, AP&T presents in this paper a hot stamping processing route for high strength aluminium alloys been suitable for production-line development and volume manufacturing.

Institutional applications of solar total-energy systems. Draft final report. Volume 2. Appendixes

Energy Technology Data Exchange (ETDEWEB)

None

1978-07-01

The appendices present the analytical basis for the analysis of solar total energy (STE) systems. A regional-climate model and a building-load requirements model are developed, along with fuel-price scenarios. Life-cycle costs are compared for conventional-utility, total energy, and STE systems. Thermal STE system design trade-offs are performed and thermal STE system performance is determined. The sensitivity of STE competitiveness to fuel prices is examined. The selection of the photovoltaic array is briefly discussed. The institutional-sector decision processes are analyzed. Hypothetical regional back-up rates and electrical-energy costs are calculated. The algorithms and equations used in operating the market model are given, and a general methodology is developed for projecting the size of the market for STE systems and applied to each of 8 institutional subsectors. (LEW)

Low-volume plus ascorbic acid vs high-volume plus simethicone bowel preparation before colonoscopy

Science.gov (United States)

Pontone, Stefano; Angelini, Rita; Standoli, Monica; Patrizi, Gregorio; Culasso, Franco; Pontone, Paolo; Redler, Adriano

2011-01-01

AIM: To investigate the effectiveness of low-volume plus ascorbic acid [polyethylene glycol plus ascorbic acid (PEG + Asc)] and high-volume plus simethicone [polyethylene glycol plus simethicone (PEG + Sim)] bowel preparations. METHODS: A total of one hundred and forty-four outpatients (76 males), aged from 20 to 84 years (median age 59.5 years), who attended our Department, were divided into two groups, age and sex matched, and underwent colonoscopy. Two questionnaires, one for patients reporting acceptability and the other for endoscopists evaluating bowel cleansing effectiveness according to validated scales, were completed. Indications, timing of examination and endoscopical findings were recorded. Biopsy forceps were used as a measuring tool in order to determine polyp endoscopic size estimation. Difficulty in completing the preparation was rated in a 5-point Likert scale (1 = easy to 5 = unable). Adverse experiences (fullness, cramps, nausea, vomiting, abdominal pain, headache and insomnia), number of evacuations and types of activities performed during preparation (walking or resting in bed) were also investigated. RESULTS: Seventy-two patients were selected for each group. The two groups were age and sex matched as well as being comparable in terms of medical history and drug therapies taken. Fourteen patients dropped out from the trial because they did not complete the preparation procedure. Ratings of global bowel cleansing examinations were considered to be adequate in 91% of PEG + Asc and 88% of PEG + Sim patients. Residual Stool Score indicated similar levels of amount and consistency of residual stool; there was a significant difference in the percentage of bowel wall visualization in favour of PEG + Sim patients. In the PEG + Sim group, 12 adenomas ≤ 10 mm diameter (5/left colon + 7/right colon) vs 9 (8/left colon + 1/right colon) in the PEG + Asc group were diagnosed. Visualization of small lesions seems to be one of the primary advantages of the

Energy conservation measures in an institutional building in sub-tropical climate in Australia

International Nuclear Information System (INIS)

Rahman, M.M.; Rasul, M.G.; Khan, M.M.K.

2010-01-01

In this study, various energy conservation measures (ECMs) on heating, ventilating and air conditioning (HVAC) and lighting systems for a four-storied institutional building in sub-tropical (hot and humid climate) Queensland, Australia are evaluated using the simulation software called DesignBuilder (DB). Base case scenario of energy consumption profiles of existing systems are analysed and simulated first then, the simulated results are verified by on-site measured data. Three categories of ECMs, namely major investment ECMs (variable air volume (VAV) systems against constant air volume (CAV); and low coefficient of performance (COP) chillers against high COP chillers); minor investment ECMs (photo electric dimming control system against general lighting, and double glazed low emittance windows against single-glazed windows) and zero investment ECMs (reset heating and cooling set point temperatures) are evaluated. It is found that the building considered in this study can save up to 41.87% energy without compromising occupancies thermal comfort by implementing the above mentioned ECMs into the existing system.

Risk factors for radiation pneumonitis after stereotactic radiation therapy for lung tumours: clinical usefulness of the planning target volume to total lung volume ratio.

Science.gov (United States)

Ueyama, Tomoko; Arimura, Takeshi; Takumi, Koji; Nakamura, Fumihiko; Higashi, Ryutaro; Ito, Soichiro; Fukukura, Yoshihiko; Umanodan, Tomokazu; Nakajo, Masanori; Koriyama, Chihaya; Yoshiura, Takashi

2018-06-01

To identify risk factors for symptomatic radiation pneumonitis (RP) after stereotactic radiation therapy (SRT) for lung tumours. We retrospectively evaluated 68 lung tumours in 63 patients treated with SRT between 2011 and 2015. RP was graded according to the National Cancer Institute-Common Terminology Criteria for Adverse Events version 4.0. SRT was delivered at 7.0-12.0 Gy per each fraction, once daily, to a total of 48-64 Gy (median, 50 Gy). Univariate analysis was performed to assess patient- and treatment-related factors, including age, sex, smoking index (SI), pulmonary function, tumour location, serum Krebs von den Lungen-6 value (KL-6), dose-volume metrics (V5, V10, V20, V30, V40 and VS5), homogeneity index of the planning target volume (PTV), PTV dose, mean lung dose (MLD), contralateral MLD and V2, PTV volume, lung volume and the PTV/lung volume ratio (PTV/Lung). Performance of PTV/Lung in predicting symptomatic RP was also analysed using receiver operating characteristic (ROC) analysis. The median follow-up period was 21 months. 10 of 63 patients (15.9%) developed symptomatic RP after SRT. On univariate analysis, V10, V20, PTV volume and PTV/Lung were significantly associated with occurrence of RP  ≥Grade 2. ROC curves indicated that symptomatic RP could be predicted using PTV/Lung [area under curve (AUC): 0.88, confidence interval (CI: 0.78-0.95), cut-off value: 1.09, sensitivity: 90.0% and specificity: 72.4%]. PTV/Lung is a good predictor of symptomatic RP after SRT. Advances in knowledge: The cases with high PTV/Lung should be carefully monitored with caution for the occurrence of RP after SRT.

Transient analysis of electromagnetic wave interactions on high-contrast scatterers using volume electric field integral equation

KAUST Repository

Sayed, Sadeed Bin; Ulku, Huseyin Arda; Bagci, Hakan

2014-01-01

A marching on-in-time (MOT)-based time domain volume electric field integral equation (TD-VEFIE) solver is proposed for accurate and stable analysis of electromagnetic wave interactions on high-contrast scatterers. The stability is achieved using

Immobilization of defense high-level waste: an assessment of technological strategies and potential regulatory goals. Volume II

International Nuclear Information System (INIS)

1979-06-01

This volume contains the following appendices: selected immobilization processes, directory of selected European organizations involved in HLW management, U.S. high-level waste inventories, and selected European HLW program

High-Volume Production of Lightweight Multijunction Solar Cells

Science.gov (United States)

Youtsey, Christopher

2015-01-01

MicroLink Devices, Inc., has transitioned its 6-inch epitaxial lift-off (ELO) solar cell fabrication process into a manufacturing platform capable of sustaining large-volume production. This Phase II project improves the ELO process by reducing cycle time and increasing the yield of large-area devices. In addition, all critical device fabrication processes have transitioned to 6-inch production tool sets designed for volume production. An emphasis on automated cassette-to-cassette and batch processes minimizes operator dependence and cell performance variability. MicroLink Devices established a pilot production line capable of at least 1,500 6-inch wafers per month at greater than 80 percent yield. The company also increased the yield and manufacturability of the 6-inch reclaim process, which is crucial to reducing the cost of the cells.

A hybrid plasmonic microresonator with high quality factor and small mode volume

International Nuclear Information System (INIS)

Lu, Qijing; Chen, Daru; Wu, Genzhu; Peng, Baojin; Xu, Jiancheng

2012-01-01

We propose a novel hybrid plasmonic microcavity which is composed of a silver nanoring and a silica toroidal microcavity. The hybrid mode of the proposed hybrid plasmonic microcavity due to the coupling between the surface plasmon polaritons (SPPs) and the dielectric mode is demonstrated with a high quality factor (>1000) and an ultrasmall mode volume (∼0.8 μm 3 ). This microcavity shows great potential in fundamental studies of nonlinear optics and cavity quantum electrodynamics (cQED) and applications in low-threshold plasmonic microlasers. (paper)

NATO Advanced Study Institute on Superconducting Electronics

CERN Document Server

Nisenhoff, Martin; Superconducting Electronics

1989-01-01

The genesis of the NATO Advanced Study Institute (ASI) upon which this volume is based, occurred during the summer of 1986 when we came to the realization that there had been significant progress during the early 1980's in the field of superconducting electronics and in applications of this technology. Despite this progress, there was a perception among many engineers and scientists that, with the possible exception of a limited number of esoteric fundamental studies and applications (e.g., the Josephson voltage standard or the SQUID magnetometer), there was no significant future for electronic systems incorporating superconducting elements. One of the major reasons for this perception was the aversion to handling liquid helium or including a closed-cycle helium liquefier. In addition, many critics felt that IBM's cancellation of its superconducting computer project in 1983 was "proof" that superconductors could not possibly compete with semiconductors in high-speed signal processing. From our persp...

A high-throughput platform for low-volume high-temperature/pressure sealed vessel solvent extractions

Energy Technology Data Exchange (ETDEWEB)

Damm, Markus [Christian Doppler Laboratory for Microwave Chemistry (CDLMC) and Institute of Chemistry, Karl-Franzens-University Graz, Heinrichstrasse 28, A-8010 Graz (Austria); Kappe, C. Oliver, E-mail: oliver.kappe@uni-graz.at [Christian Doppler Laboratory for Microwave Chemistry (CDLMC) and Institute of Chemistry, Karl-Franzens-University Graz, Heinrichstrasse 28, A-8010 Graz (Austria)

2011-11-30

Highlights: Black-Right-Pointing-Pointer Parallel low-volume coffee extractions in sealed-vessel HPLC/GC vials. Black-Right-Pointing-Pointer Extractions are performed at high temperatures and pressures (200 Degree-Sign C/20 bar). Black-Right-Pointing-Pointer Rapid caffeine determination from the liquid phase. Black-Right-Pointing-Pointer Headspace analysis of volatiles using solid-phase microextraction (SPME). - Abstract: A high-throughput platform for performing parallel solvent extractions in sealed HPLC/GC vials inside a microwave reactor is described. The system consist of a strongly microwave-absorbing silicon carbide plate with 20 cylindrical wells of appropriate dimensions to be fitted with standard HPLC/GC autosampler vials serving as extraction vessels. Due to the possibility of heating up to four heating platforms simultaneously (80 vials), efficient parallel analytical-scale solvent extractions can be performed using volumes of 0.5-1.5 mL at a maximum temperature/pressure limit of 200 Degree-Sign C/20 bar. Since the extraction and subsequent analysis by either gas chromatography or liquid chromatography coupled with mass detection (GC-MS or LC-MS) is performed directly from the autosampler vial, errors caused by sample transfer can be minimized. The platform was evaluated for the extraction and quantification of caffeine from commercial coffee powders assessing different solvent types, extraction temperatures and times. For example, 141 {+-} 11 {mu}g caffeine (5 mg coffee powder) were extracted during a single extraction cycle using methanol as extraction solvent, whereas only 90 {+-} 11 were obtained performing the extraction in methylene chloride, applying the same reaction conditions (90 Degree-Sign C, 10 min). In multiple extraction experiments a total of {approx}150 {mu}g caffeine was extracted from 5 mg commercial coffee powder. In addition to the quantitative caffeine determination, a comparative qualitative analysis of the liquid phase coffee

A high-throughput platform for low-volume high-temperature/pressure sealed vessel solvent extractions

International Nuclear Information System (INIS)

Damm, Markus; Kappe, C. Oliver

2011-01-01

Highlights: ► Parallel low-volume coffee extractions in sealed-vessel HPLC/GC vials. ► Extractions are performed at high temperatures and pressures (200 °C/20 bar). ► Rapid caffeine determination from the liquid phase. ► Headspace analysis of volatiles using solid-phase microextraction (SPME). - Abstract: A high-throughput platform for performing parallel solvent extractions in sealed HPLC/GC vials inside a microwave reactor is described. The system consist of a strongly microwave-absorbing silicon carbide plate with 20 cylindrical wells of appropriate dimensions to be fitted with standard HPLC/GC autosampler vials serving as extraction vessels. Due to the possibility of heating up to four heating platforms simultaneously (80 vials), efficient parallel analytical-scale solvent extractions can be performed using volumes of 0.5–1.5 mL at a maximum temperature/pressure limit of 200 °C/20 bar. Since the extraction and subsequent analysis by either gas chromatography or liquid chromatography coupled with mass detection (GC–MS or LC–MS) is performed directly from the autosampler vial, errors caused by sample transfer can be minimized. The platform was evaluated for the extraction and quantification of caffeine from commercial coffee powders assessing different solvent types, extraction temperatures and times. For example, 141 ± 11 μg caffeine (5 mg coffee powder) were extracted during a single extraction cycle using methanol as extraction solvent, whereas only 90 ± 11 were obtained performing the extraction in methylene chloride, applying the same reaction conditions (90 °C, 10 min). In multiple extraction experiments a total of ∼150 μg caffeine was extracted from 5 mg commercial coffee powder. In addition to the quantitative caffeine determination, a comparative qualitative analysis of the liquid phase coffee extracts and the headspace volatiles was performed, placing special emphasis on headspace analysis using solid-phase microextraction (SPME

Disposable photonic integrated circuits for evanescent wave sensors by ultra-high volume roll-to-roll method.

Science.gov (United States)

Aikio, Sanna; Hiltunen, Jussi; Hiitola-Keinänen, Johanna; Hiltunen, Marianne; Kontturi, Ville; Siitonen, Samuli; Puustinen, Jarkko; Karioja, Pentti

2016-02-08

Flexible photonic integrated circuit technology is an emerging field expanding the usage possibilities of photonics, particularly in sensor applications, by enabling the realization of conformable devices and introduction of new alternative production methods. Here, we demonstrate that disposable polymeric photonic integrated circuit devices can be produced in lengths of hundreds of meters by ultra-high volume roll-to-roll methods on a flexible carrier. Attenuation properties of hundreds of individual devices were measured confirming that waveguides with good and repeatable performance were fabricated. We also demonstrate the applicability of the devices for the evanescent wave sensing of ambient refractive index. The production of integrated photonic devices using ultra-high volume fabrication, in a similar manner as paper is produced, may inherently expand methods of manufacturing low-cost disposable photonic integrated circuits for a wide range of sensor applications.

To what extent do long-duration high-volume dam releases influence river-aquifer interactions? A case study in New South Wales, Australia

Science.gov (United States)

Graham, P. W.; Andersen, M. S.; McCabe, M. F.; Ajami, H.; Baker, A.; Acworth, I.

2015-03-01

Long-duration high-volume dam releases are unique anthropogenic events with no naturally occurring equivalents. The impact from such dam releases on a downstream Quaternary alluvial aquifer in New South Wales, Australia, is assessed. It is observed that long-duration (>26 days), high-volume dam releases (>8,000 ML/day average) result in significant variations in river-aquifer interactions. These variations include a flux from the river to the aquifer up to 6.3 m3/day per metre of bank (at distances of up to 330 m from the river bank), increased extent and volume of recharge/bank storage, and a long-term (>100 days) reversal of river-aquifer fluxes. In contrast, during lower-volume events (bank. A groundwater-head prediction model was constructed and river-aquifer fluxes were calculated; however, predicted fluxes from this method showed poor correlation to fluxes calculated using actual groundwater heads. Long-duration high-volume dam releases have the potential to skew estimates of long-term aquifer resources and detrimentally alter the chemical and physical properties of phreatic aquifers flanking the river. The findings have ramifications for improved integrated management of dam systems and downstream aquifers.

Paul Scherrer Institute Scientific Report 2000. Volume II: Life Sciences

Energy Technology Data Exchange (ETDEWEB)

Jaussi, Rolf; Gschwend, Beatrice [eds.

2001-07-01

The existing activities of the Department of Life Sciences have grown out of the specific know-how and the unique experimental possibilities available at PSI. Primarily, these have been and are complex facilities for using particle beams (protons, neutrons) on the one hand and know-how in the production, handling and chemistry of radionuclides on the other. The common theme of the department has thus been the study and use of various types of radiation in therapy and diagnostics of human disease and in particular of cancer. The four units active in this area are: The major activity in the Radiation Medicine unit is Proton Therapy, which aims to further develop and optimise the world-wide unique spot scanning facility for irradiating malignant tumours with minimal damage to surrounding healthy tissues, including the established OPTIS program for the treatment of eye tumours. The Centre for Radiopharmaceutical Science represents a joint activity of PSI with the Swiss Federal Institute of Technology (ETHZ) and the University of Zurich. Its major goals are the development of novel tumour targeted radioconjugates for cancer diagnosis and therapy and the production and evaluation of new PET (positron emission tomography) radiotracers for various applications in neuro physiology and drug development. The Institute of Medical Radiobiology analyses questions of the molecular biology of DNA repair. It is a joint activity of PSI and the University of Zurich. The newly established Structural Biology group is still in the build-up phase. A strong in-house research activity in macromolecular crystallography will complement the more user-oriented protein crystallography beam line, which is being built at the Swiss Light Source (SLS). In particular, tumour targeting by molecular vehicles and DNA repair are areas where structural information can provide important insights. Progress in 2000 in these topical areas is described in this report. A list of scientific publications in 2000

Paul Scherrer Institute Scientific Report 2000. Volume II: Life Sciences

International Nuclear Information System (INIS)

Jaussi, Rolf; Gschwend, Beatrice

2001-01-01

The existing activities of the Department of Life Sciences have grown out of the specific know-how and the unique experimental possibilities available at PSI. Primarily, these have been and are complex facilities for using particle beams (protons, neutrons) on the one hand and know-how in the production, handling and chemistry of radionuclides on the other. The common theme of the department has thus been the study and use of various types of radiation in therapy and diagnostics of human disease and in particular of cancer. The four units active in this area are: The major activity in the Radiation Medicine unit is Proton Therapy, which aims to further develop and optimise the world-wide unique spot scanning facility for irradiating malignant tumours with minimal damage to surrounding healthy tissues, including the established OPTIS program for the treatment of eye tumours. The Centre for Radiopharmaceutical Science represents a joint activity of PSI with the Swiss Federal Institute of Technology (ETHZ) and the University of Zurich. Its major goals are the development of novel tumour targeted radioconjugates for cancer diagnosis and therapy and the production and evaluation of new PET (positron emission tomography) radiotracers for various applications in neuro physiology and drug development. The Institute of Medical Radiobiology analyses questions of the molecular biology of DNA repair. It is a joint activity of PSI and the University of Zurich. The newly established Structural Biology group is still in the build-up phase. A strong in-house research activity in macromolecular crystallography will complement the more user-oriented protein crystallography beam line, which is being built at the Swiss Light Source (SLS). In particular, tumour targeting by molecular vehicles and DNA repair are areas where structural information can provide important insights. Progress in 2000 in these topical areas is described in this report. A list of scientific publications in 2000

[Evaluation of tidal volume delivered by ventilators during volume-controlled ventilation].

Science.gov (United States)

Zhou, Juan; Yan, Yong; Cao, Desen

2014-12-01

To study the ways which ensure the delivery of enough tidal volume to patients under various conditions close to the demand of the physician. The volume control ventilation model was chosen, and the simulation lung type was active servo lung ASL 5000 or Michigan lung 1601. The air resistance, air compliance and lung type in simulation lungs were set. The tidal volume was obtained from flow analyzer PF 300. At the same tidal volume, the displaying values of tidal volume of E5, Servo i, Evital 4, and Evital XL ventilators with different lung types of patient, compliance of gas piping, leakage, gas types, etc. were evaluated. With the same setting tidal volume of a same ventilator, the tidal volume delivered to patients was different with different lung types of patient, compliance of gas piping, leakage, gas types, etc. Reducing compliance and increasing resistance of the patient lungs caused high peak airway pressure, the tidal volume was lost in gas piping, and the tidal volume be delivered to the patient lungs was decreased. If the ventilator did not compensate to leakage, the tidal volume delivered to the patient lungs was decreased. When the setting gas type of ventilator did not coincide with that applying to the patient, the tidal volume be delivered to the patient lungs might be different with the setting tidal volume of ventilator. To ensure the delivery of enough tidal volume to patients close to the demand of the physician, containable factors such as the compliance of gas piping, leakage, and gas types should be controlled.

Sampling of high amounts of bioaerosols using a high-volume electrostatic field sampler

DEFF Research Database (Denmark)

Madsen, A. M.; Sharma, Anoop Kumar

2008-01-01

For studies of the biological effects of bioaerosols, large samples are necessary. To be able to sample enough material and to cover the variations in aerosol content during and between working days, a long sampling time is necessary. Recently, a high-volume transportable electrostatic field...... and 315 mg dust (net recovery of the lyophilized dust) was sampled during a period of 7 days, respectively. The sampling rates of the electrostatic field samplers were between 1.34 and 1.96 mg dust per hour, the value for the Gravikon was between 0.083 and 0.108 mg dust per hour and the values for the GSP...... samplers were between 0.0031 and 0.032 mg dust per hour. The standard deviations of replica samplings and the following microbial analysis using the electrostatic field sampler and GSP samplers were at the same levels. The exposure to dust in the straw storage was 7.7 mg m(-3) when measured...

Measuring the volume of cingulate cortex in Chinese normal adults of the Han nationality on the high-resolution MRI

International Nuclear Information System (INIS)

Zhang Chao; Chen Nan; Wang Xing; Li Kuncheng; Zhou Xin; Zhuo Yan; Chen Lin

2010-01-01

correlated with age (r=-0.330, -0.324, -0.169, -0.243, P<0.05), though the correlation coefficient is not high. Conclusions: Cingulate cortex volume could be accurately measured on the high-resolution MRI with 3D volume analysis software, which can provide morphological data for the construction of database for Chinese Standard Brain. The results may provide normal range for the diagnosis of the volumetric deficits of cingulate cortex. (authors)

[Effect of different volumes of fluid resuscitation on hemorrhagic shock with pulmonary edema at high altitude in the unacclimated rat].

Science.gov (United States)

Liu, Liang-ming; Hu, De-yao; Liu, Jian-cang; Li, Ping; Liu, Hou-dong; Xiao, Nan; Zhou, Xue-wu; Tian, Kun-lun; Huo, Xiao-ping; Shi, Quan-gui; He, Yan-mei; Yin, Zuo-ming

2003-05-01

To study the effects of different volumes of fluid resuscitation on hemorrhagic shock with pulmonary edema at high altitude in the unacclimated rat. One hundred and twenty-six SD rats transported to Lasa, Tibet, 3 760 meters above the sea level, were anesthetized one week later with sodium pentobarbital (30 mg/kg, intraperitoneal). Hemorrhagic shock with pulmonary edema model was induced by hemorrhage (50 mm Hg for 1 hour, 1 mmHg=0.133 kPa) plus intravenous injection of oleic acid (50 microl/kg). Experiments were then conducted in two parts. Sixty-three rats in part I were equally divided into nine groups (n=7): normal control, hemorrhagic shock control, hemorrhagic shock with pulmonary edema (HSPE) without fluid infusion, HSPE plus infusing lactated Ringer's solution (LR) with 0.5-, 1-, 1.5-, 2- or 3- fold volume shed blood, and 1 volume of LR plus mannitol (10 ml/kg). Hemodynamic parameters including mean arterial blood pressure (MAP), left intraventricular systolic pressure (LVSP) and the maximal change rate of intraventricular pressure rise or decline (+/- dp/dt max) were observed at 15, 30, 60 and 120 minutes after infusion, blood gases were measured at 30 and 120 minutes after infusion and the water content of lung and brain was determined at 120 minutes after infusion. In part II, additional 63 rats were used to observe the effect of different volumes of fluid resuscitation on survival time of HSPE rats. 0.5 volume of LR infusion significantly improved MAP, LVSP and +/- dp/dt max, prolonged the survival time of HSPE animals (all P<0.01), while it did not increase the water content of lung and brain and had no marked influence on blood gases. One volume of LR infusion slightly improved hemodynamic parameters, prolonged the survival time and increased the water content of lung. More than 1 volume of LR infusion including 1.5-, 2- and 3- fold volume LR deteriorated the hemodynamic parameters and decreased the survival time of shocked animal, meanwhile they

High-voltage electrode optimization towards uniform surface treatment by a pulsed volume discharge

International Nuclear Information System (INIS)

Ponomarev, A V; Pedos, M S; Scherbinin, S V; Mamontov, Y I; Ponomarev, S V

2015-01-01

In this study, the shape and material of the high-voltage electrode of an atmospheric pressure plasma generation system were optimised. The research was performed with the goal of achieving maximum uniformity of plasma treatment of the surface of the low-voltage electrode with a diameter of 100 mm. In order to generate low-temperature plasma with the volume of roughly 1 cubic decimetre, a pulsed volume discharge was used initiated with a corona discharge. The uniformity of the plasma in the region of the low-voltage electrode was assessed using a system for measuring the distribution of discharge current density. The system's low-voltage electrode - collector - was a disc of 100 mm in diameter, the conducting surface of which was divided into 64 radially located segments of equal surface area. The current at each segment was registered by a high-speed measuring system controlled by an ARM™-based 32-bit microcontroller. To facilitate the interpretation of results obtained, a computer program was developed to visualise the results. The program provides a 3D image of the current density distribution on the surface of the low-voltage electrode. Based on the results obtained an optimum shape for a high-voltage electrode was determined. Uniformity of the distribution of discharge current density in relation to distance between electrodes was studied. It was proven that the level of non-uniformity of current density distribution depends on the size of the gap between electrodes. Experiments indicated that it is advantageous to use graphite felt VGN-6 (Russian abbreviation) as the material of the high-voltage electrode's emitting surface. (paper)

Volume holographic memory

Directory of Open Access Journals (Sweden)

Cornelia Denz

2000-05-01

Full Text Available Volume holography represents a promising alternative to existing storage technologies. Its parallel data storage leads to high capacities combined with short access times and high transfer rates. The design and realization of a compact volume holographic storage demonstrator is presented. The technique of phase-coded multiplexing implemented to superimpose many data pages in a single location enables to store up to 480 holograms per storage location without any moving parts. Results of analog and digital data storage are shown and real time optical image processing is demonstrated.

Risk adjustment for case mix and the effect of surgeon volume on morbidity.

Science.gov (United States)

Maas, Matthew B; Jaff, Michael R; Rordorf, Guy A

2013-06-01

Retrospective studies of large administrative databases have shown higher mortality for procedures performed by low-volume surgeons, but the adequacy of risk adjustment in those studies is in doubt. To determine whether the relationship between surgeon volume and outcomes is an artifact of case mix using a prospective sample of carotid endarterectomy cases. Observational cohort study from January 1, 2008, through December 31, 2010, with preoperative, immediate postoperative, and 30-day postoperative assessments acquired by independent monitors. Urban, tertiary academic medical center. All 841 patients who underwent carotid endarterectomy performed by a vascular surgeon or cerebrovascular neurosurgeon at the institution. Carotid endarterectomy without another concurrent surgery. Stroke, death, and other surgical complications occurring within 30 days of surgery along with other case data. A low-volume surgeon performed 40 or fewer cases per year. Variables used in a comparison administrative database study, as well as variables identified by our univariate analysis, were used for adjusted analyses to assess for an association between low-volume surgeons and the rate of stroke and death as well as other complications. RESULTS The rate of stroke and death was 6.9% for low-volume surgeons and 2.0% for high-volume surgeons (P = .001). Complications were similarly higher (13.4% vs 7.2%, P = .008). Low-volume surgeons performed more nonelective cases. Low-volume surgeons were significantly associated with stroke and death in the unadjusted analysis as well as after adjustment with variables used in the administrative database study (odds ratio, 3.61; 95% CI, 1.70-7.67, and odds ratio, 3.68; 95% CI, 1.72-7.89, respectively). However, adjusting for the significant disparity of American Society of Anesthesiologists Physical Status classification in case mix eliminated the effect of surgeon volume on the rate of stroke and death (odds ratio, 1.65; 95% CI, 0.59-4.64) and other

Increased cartilage volume after injection of hyaluronic acid in osteoarthritis knee patients who underwent high tibial osteotomy.

Science.gov (United States)

Chareancholvanich, Keerati; Pornrattanamaneewong, Chaturong; Narkbunnam, Rapeepat

2014-06-01

High tibial osteotomy (HTO) is a surgical procedure used to correct abnormal mechanical loading of the knee joint; additionally, intra-articular hyaluronic acid injections have been shown to restore the viscoelastic properties of synovial fluid and balance abnormal biochemical processes. It was hypothesized that combining HTO with intra-articular hyaluronic acid injections would have benefit to improve the cartilage volume of knee joints. Forty patients with medial compartment knee osteoarthritis (OA) were randomly placed into 1 of 2 groups. The study group (n = 20) received 2 cycles (at 6-month intervals) of 5 weekly intra-articular hyaluronic acid injections after HTO operation. The control group (n = 20) did not receive any intra-articular injections after HTO surgery. Cartilage volume (primary outcome) was assessed by magnetic resonance imaging (MRI) pre-operatively and 1 year post-operatively. Treatment efficacy (secondary outcomes) was evaluated with the Western Ontario and McMaster Universities OA Index (WOMAC) and by the comparison of the total rescue medication (paracetamol/diclofenac) used (weeks 6, 12, 24, 48). MRI studies showed a significant increase in total cartilage volume (p = 0.033), lateral femoral cartilage volume (p = 0.044) and lateral tibial cartilage volume (p = 0.027) in the study group. Cartilage volume loss was detected at the lateral tibial plateau in the control group. There were significant improvements after surgery in both groups for all subscales of WOMAC scores (p hyaluronic acid injections may be beneficial for increasing total cartilage volume and preventing the loss of lateral tibiofemoral joint cartilage after HTO. Therapeutic study, Level I.

Risky Business: An Integrated Institutional Theory for Understanding High-Risk Decision Making in Higher Education

Science.gov (United States)

Turner, Lauren A.; Angulo, A. J.

2018-01-01

Lauren A. Turner and A. J. Angulo explore how institutional theory can be applied to explain variance in higher education organizational strategies. Given strong regulatory, normative, and cultural-cognitive pressures to conform, they ask, why do some colleges engage in high-risk decision making? To answer this, they bring together classic and…

Investigation of high-current low pressure quasistationary volume discharge in cross-field ExH

International Nuclear Information System (INIS)

Bashutin, O.A.; Vovchenko, E.D.; Kirnev, G.S.

1995-01-01

Different types of high current discharge permitted to create large volume of high density homogeneous plasma are widely used in modern technique. Such discharges are applied as plasma emitters of charged particles and also in various technologies for sputtering, implantation and etching of materials. The results of a plasma electron density dynamics investigation of low pressure quasistationary volume discharge in cross-field E x H is described in this paper. The discharge was created in a quadrupole magnetic system with special form electrodes and has following characteristics current up to 1,8 kA, voltage on the interval 80-120 V, existence time up to 1,5 ms. The discharge conserves diffusive character of plasma and cathode layer on all current range. On a first research stage plasma parameters of discharge were determined by means of Langmuir probe, that could been used in central discharge region only, where magnetic field was equal to zero. An obtained plasma density was reached 1,5*10 15 cm -3 with electron temperature T e =10 eV. The research of discharge plasma in regions with magnetic field had required to use interferometric measurement technique

Cerebral gray matter volume losses in essential tremor: A case-control study using high resolution tissue probability maps.

Science.gov (United States)

Cameron, Eric; Dyke, Jonathan P; Hernandez, Nora; Louis, Elan D; Dydak, Ulrike

2018-03-10

Essential tremor (ET) is increasingly recognized as a multi-dimensional disorder with both motor and non-motor features. For this reason, imaging studies are more broadly examining regions outside the cerebellar motor loop. Reliable detection of cerebral gray matter (GM) atrophy requires optimized processing, adapted to high-resolution magnetic resonance imaging (MRI). We investigated cerebral GM volume loss in ET cases using automated segmentation of MRI T1-weighted images. MRI was acquired on 47 ET cases and 36 controls. Automated segmentation and voxel-wise comparisons of volume were performed using Statistical Parametric Mapping (SPM) software. To improve upon standard protocols, the high-resolution International Consortium for Brain Mapping (ICBM) 2009a atlas and tissue probability maps were used to process each subject image. Group comparisons were performed: all ET vs. Controls, ET with head tremor (ETH) vs. Controls, and severe ET vs. An analysis of variance (ANOVA) was performed between ET with and without head tremor and controls. Age, sex, and Montreal Cognitive Assessment (MoCA) score were regressed out from each comparison. We were able to consistently identify regions of cerebral GM volume loss in ET and in ET subgroups in the posterior insula, superior temporal gyri, cingulate cortex, inferior frontal gyri and other occipital and parietal regions. There were no significant increases in GM volume in ET in any comparisons with controls. This study, which uses improved methodologies, provides evidence that GM volume loss in ET is present beyond the cerebellum, and in fact, is widespread throughout the cerebrum as well. Copyright © 2018 Elsevier Ltd. All rights reserved.

Full commitment of top management in Macedonian High Education Institutions

OpenAIRE

Taskov, Nako; Mitreva, Elizabeta; Sazdova, Julijana; Dimitrov, Nikola; Metodijeski, Dejan

2014-01-01

Purpose: This paper presents an analysis regarding the condition of Macedonian higher education institutions through one of the criteria for receiving a European Quality Award in the direction of the activities undertaken in relation to achieve the planned satisfaction of all those who have financial interest in it. Methodology: The research is designed as an attempt to depict the existing condition within Ten Macedonian higher education institutions regarding quality system design and ...

COOMET.RI(II)-S1.Rn-222 (169/UA/98): Rn-222 volume activity comparison

International Nuclear Information System (INIS)

Skliarov, V.; Rottger, A.; Honig, A.; Korostin, S.; Kuznetsov, S.; Lapenas, A.; Milevsky, V.; Ivaniukovich, A.; Kharitonov, I.; Sepman, S.

2009-01-01

According to a first program, a supplementary comparison of Rn-222 volume activity was drawn up as a bilateral supplementary comparison between NSC 'Institute of Metrology', Ukraine, and VNIIFTRI, Russia. It took place in March 2005. In April 2005, at the 5. meeting of COOMET held in Braunschweig (Germany), representatives of these institutes exchanged data which showed the comparability of the national standards of Ukraine and Russia for the check points. During the discussion of the procedure some other institutes decided to join the comparison program, which was extended to BelGIM (Belarus), PTB (Germany), VNIIM (Russia) and RMTC (Latvia). The national standards of volume activity of radon-222 were thus calibrated using one standard radon radiometer as the transfer standard. Results are shown in the Final Report of the comparison. (authors)

COOMET.RI(II)-S1.Rn-222 (169/UA/98): Rn-222 volume activity comparison

Energy Technology Data Exchange (ETDEWEB)

Skliarov, V. [National Scientific Centre, Institute of Metrology (NSC IM), Kharkiv (Ukraine); Rottger, A.; Honig, A. [Physikalisch-Technische Bundesanstalt (PTB), Braunschweig (Germany); Korostin, S.; Kuznetsov, S. [All-Russian Scientific Research Institute of Physical, Technical and Radio Measurements (VNIIFTRI), Moscow Region, Mendeleyevo (Russian Federation); Lapenas, A. [Latvian National Metrology Centre Ltd, Radiation Metrology and Testing Centre (RMTC), Salaspils (Latvia); Milevsky, V.; Ivaniukovich, A. [Belarussian State Institute of Metrology (BelGIM), Minsk (Belarus); Kharitonov, I.; Sepman, S. [D I Mendeleyev Institute of metrology (VNIIM), Saint Petersburg (Russian Federation)

2009-06-15

According to a first program, a supplementary comparison of Rn-222 volume activity was drawn up as a bilateral supplementary comparison between NSC 'Institute of Metrology', Ukraine, and VNIIFTRI, Russia. It took place in March 2005. In April 2005, at the 5. meeting of COOMET held in Braunschweig (Germany), representatives of these institutes exchanged data which showed the comparability of the national standards of Ukraine and Russia for the check points. During the discussion of the procedure some other institutes decided to join the comparison program, which was extended to BelGIM (Belarus), PTB (Germany), VNIIM (Russia) and RMTC (Latvia). The national standards of volume activity of radon-222 were thus calibrated using one standard radon radiometer as the transfer standard. Results are shown in the Final Report of the comparison. (authors)

Pore volume is most highly correlated with the visual assessment of skin pores.

Science.gov (United States)

Kim, S J; Shin, M K; Back, J H; Koh, J S

2014-11-01

Many studies have been focused on evaluating assessment techniques for facial pores amid growing attention on skin care. Ubiquitous techniques used to assess the size of facial pores include visual assessment, cross-section images of the skin surface, and profilometric analysis of silicone replica of the facial skin. In addition, there are indirect assessment methods, including observation of pores based on confocal laser scanning microscopy and the analysis of sebum secretion and skin elasticity. The aim of this study was to identify parameters useful in estimating pore of surface in normal skin. The severity of pores on the cheek area by frontal optical images was divided on a 0-6 scale with '0' being faint and small pore and '6' being obvious and large pore. After the photos of the frontal cheek of 32 women aged between 35 and 49 were taken, the size of their pores was measured on a 0-6 scale; and the correlation between visual grading of pore and various evaluations (pore volume by 3-D image, pore area and number by Optical Image Analyzer) contributing to pore severity investigated using direct, objective, and noninvasive evaluations. The visual score revealed that the size of pores was graded on a 1-6 scale. Visual grading of pore was highly correlated with pore volume measured from 3-D images and pore area measured from 2-D optical images in the order (P pore was also slightly correlated with the number of pores in size of over 0.04 mm(2) (P pore score and pore volume can be explained by 3-D structural characteristics of pores. It is concluded that pore volume and area serve as useful parameters in estimating pore of skin surface. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Brief report: Volume dependence of Grüneisen parameter for solids

Indian Academy of Sciences (India)

Brief report: Volume dependence of Grüneisen parameter for solids under extreme ... Shivalik Institute of Engineering and Technology, Aliyaspur, Ambala 133 206, India ... Accepted: 1 October 2015; Final version published online: 9 July 2016 ...

Can the Concept of Integrative and Segregative Institutions Contribute to the Framing of Institutions of Sustainability?

Directory of Open Access Journals (Sweden)

Konrad Hagedorn

2015-01-01

Full Text Available This paper begins with the question “What is special about those institutions that bring about sustainability”? In an attempt to answer this, I use the Institutions of Sustainability (IoS framework, which structures sustainability analytically according to four main categories, namely: transactions, actors, institutions and governance structures. I then argue that sustainability has to do with balancing two sorts of costs an actor may face while being constrained by institutions. One is the costs from the integrative effects of institutions on his individual decision making. The other is the costs from the segregative effect of institutions. In this way, sustainability can be understood as societies’ compromise between institutions that integrate individual actors’ decisions in a wider system, holding them fully responsible for more or less all of the effects of their choices and those institutions that partly free individual decision makers from parts of such responsibilities. If a governance problem is characterized by a high degree of “decomposability”, segregative rules may be sufficient. The more a governance problem is characterized by complexity due to low modularity and high functional interdependencies, the more accurate integrative rules may be. The paper concludes by identifying “sustainability area of institutional embedding” as a regulative idea in understanding sustainability.

Formal Institutions and Subjective Wellbeing

DEFF Research Database (Denmark)

Bjørnskov, Christian; Dreher, Axel; Fischer, Justina A.V.

2010-01-01

A long tradition in economics explores the association between the quality of formal institutions and economic performance. The literature on the relationship between such institutions and happiness is, however, rather limited, and inconclusive. In this paper, we revisit the findings from recent...... cross-country studies on the institution-happiness association. Our findings suggest that their conclusions are qualitatively rather insensitive to the specific measure of 'happiness' used, while the associations between formal institutions and subjective well-being differ among poor and rich countries....... Separating different types of institutional quality, we find that in low-income countries the effects of economic-judicial institutions on happiness dominate those of political institutions, while analyses restricted to middle- and high-income countries show strong support for an additional beneficial effect...

The high throughput biomedicine unit at the institute for molecular medicine Finland: high throughput screening meets precision medicine.

Science.gov (United States)

Pietiainen, Vilja; Saarela, Jani; von Schantz, Carina; Turunen, Laura; Ostling, Paivi; Wennerberg, Krister

2014-05-01

The High Throughput Biomedicine (HTB) unit at the Institute for Molecular Medicine Finland FIMM was established in 2010 to serve as a national and international academic screening unit providing access to state of the art instrumentation for chemical and RNAi-based high throughput screening. The initial focus of the unit was multiwell plate based chemical screening and high content microarray-based siRNA screening. However, over the first four years of operation, the unit has moved to a more flexible service platform where both chemical and siRNA screening is performed at different scales primarily in multiwell plate-based assays with a wide range of readout possibilities with a focus on ultraminiaturization to allow for affordable screening for the academic users. In addition to high throughput screening, the equipment of the unit is also used to support miniaturized, multiplexed and high throughput applications for other types of research such as genomics, sequencing and biobanking operations. Importantly, with the translational research goals at FIMM, an increasing part of the operations at the HTB unit is being focused on high throughput systems biological platforms for functional profiling of patient cells in personalized and precision medicine projects.

Challenges and solutions for high-volume testing of silicon photonics

Science.gov (United States)

Polster, Robert; Dai, Liang Yuan; Oikonomou, Michail; Cheng, Qixiang; Rumley, Sebastien; Bergman, Keren

2018-02-01

The first generation of silicon photonic products is now commercially available. While silicon photonics possesses key economic advantages over classical photonic platforms, it has yet to become a commercial success because these advantages can be fully realized only when high-volume testing of silicon photonic devices is made possible. We discuss the costs, challenges, and solutions of photonic chip testing as reported in the recent research literature. We define and propose three underlying paradigms that should be considered when creating photonic test structures: Design for Fast Coupling, Design for Minimal Taps, and Design for Parallel Testing. We underline that a coherent test methodology must be established prior to the design of test structures, and demonstrate how an optimized methodology dramatically reduces the burden when designing for test, by reducing the needed complexity of test structures.

Assessing the Potential for Rooftop Rainwater Harvesting from Large Public Institutions.

Science.gov (United States)

Adugna, Dagnachew; Jensen, Marina Bergen; Lemma, Brook; Gebrie, Geremew Sahilu

2018-02-14

As in many other cities, urbanization coupled with population growth worsens the water supply problem of Addis Ababa, Ethiopia, with a water supply deficit of 41% in 2016. To investigate the potential contribution of rooftop rainwater harvesting (RWH) from large public institutions, 320 such institutions were selected and grouped into 11 categories, from which 25-30% representative 588 rooftops were digitalized and the potential RWH volume computed based on a ten-year rainfall dataset. When comparing the resulting RWH potential with the water consumption, up to 2.3% of the annual, potable water supply can be provided. If reused only within one's own institution, the self-sufficiency varies from 0.9 to 649%. Non-uniform rainfall patterns add uncertainty to these numbers, since the size of the storage tank becomes critical for coverage in the dry season from October to May. Despite the low replacement potential at the city level, RWH from large institutions will enable a significant volume of potable water to be transferred to localities critically suffering from water shortage. Further, large institutions may demonstrate how RWH can be practiced, thus acting as a frontrunner for the dissemination of RWH to other types of rooftops. To narrow the water supply gap, considering rooftop RWH as an alternative water supply source is recommended. However, the present study assumed that financial constraints to install large sized storage tanks are considered as a possible challenge. Thus, future research is needed to investigate the cost-benefit balance along with the invention of a cheap storage tank as they may affect the potential contribution of RWH from rooftops.

Assessing the Potential for Rooftop Rainwater Harvesting from Large Public Institutions

Directory of Open Access Journals (Sweden)

Dagnachew Adugna

2018-02-01

Full Text Available As in many other cities, urbanization coupled with population growth worsens the water supply problem of Addis Ababa, Ethiopia, with a water supply deficit of 41% in 2016. To investigate the potential contribution of rooftop rainwater harvesting (RWH from large public institutions, 320 such institutions were selected and grouped into 11 categories, from which 25–30% representative 588 rooftops were digitalized and the potential RWH volume computed based on a ten-year rainfall dataset. When comparing the resulting RWH potential with the water consumption, up to 2.3% of the annual, potable water supply can be provided. If reused only within one’s own institution, the self-sufficiency varies from 0.9 to 649%. Non-uniform rainfall patterns add uncertainty to these numbers, since the size of the storage tank becomes critical for coverage in the dry season from October to May. Despite the low replacement potential at the city level, RWH from large institutions will enable a significant volume of potable water to be transferred to localities critically suffering from water shortage. Further, large institutions may demonstrate how RWH can be practiced, thus acting as a frontrunner for the dissemination of RWH to other types of rooftops. To narrow the water supply gap, considering rooftop RWH as an alternative water supply source is recommended. However, the present study assumed that financial constraints to install large sized storage tanks are considered as a possible challenge. Thus, future research is needed to investigate the cost-benefit balance along with the invention of a cheap storage tank as they may affect the potential contribution of RWH from rooftops.

1997 Summer Research Program (SRP), High School Apprenticeship Program (HSAP), Final Reports, Volume 13, Phillips Laboratory

National Research Council Canada - National Science Library

Moore, Gary

1997-01-01

The United States Air Force Summer Research Program (USAF-SRP) is designed to introduce university, college, and technical institute faculty members, graduate students, and high school students to Air Force research...

Variation in critical care unit admission rates and outcomes for patients with acute coronary syndromes or heart failure among high- and low-volume cardiac hospitals.

Science.gov (United States)

van Diepen, Sean; Bakal, Jeffrey A; Lin, Meng; Kaul, Padma; McAlister, Finlay A; Ezekowitz, Justin A

2015-02-27

Little is known about cross-hospital differences in critical care units admission rates and related resource utilization and outcomes among patients hospitalized with acute coronary syndromes (ACS) or heart failure (HF). Using a population-based sample of 16,078 patients admitted to a critical care unit with a primary diagnosis of ACS (n=14,610) or HF (n=1467) between April 1, 2003 and March 31, 2013 in Alberta, Canada, we stratified hospitals into high (>250), medium (200 to 250), or low (<200) volume based on their annual volume of all ACS and HF hospitalization. The percentage of hospitalized patients admitted to critical care units varied across low, medium, and high-volume hospitals for both ACS and HF as follows: 77.9%, 81.3%, and 76.3% (P<0.001), and 18.0%, 16.3%, and 13.0% (P<0.001), respectively. Compared to low-volume units, critical care patients with ACS and HF admitted to high-volume hospitals had shorter mean critical care stays (56.6 versus 95.6 hours, P<0.001), more critical care procedures (1.9 versus 1.2 per patient, <0.001), and higher resource-intensive weighting (2.8 versus 1.5, P<0.001). No differences in in-hospital mortality (5.5% versus 6.2%, adjusted odds ratio 0.93; 95% CI, 0.61 to 1.41) were observed between high- and low-volume hospitals; however, 30-day cardiovascular readmissions (4.6% versus 6.8%, odds ratio 0.77; 95% CI, 0.60 to 0.99) and cardiovascular emergency-room visits (6.6% versus 9.5%, odds ratio 0.80; 95% CI, 0.69 to 0.94) were lower in high-volume compared to low-volume hospitals. Outcomes stratified by ACS or HF admission diagnosis were similar. Cardiac patients hospitalized in low-volume hospitals were more frequently admitted to critical care units and had longer hospitals stays despite lower resource-intensive weighting. These findings may provide opportunities to standardize critical care utilization for ACS and HF patients across high- and low-volume hospitals. © 2015 The Authors. Published on behalf of the American

ACUTE EFFECTS OF STATIC STRETCHING, DYNAMIC EXERCISES, AND HIGH VOLUME UPPER EXTREMITY PLYOMETRIC ACTIVITY ON TENNIS SERVE PERFORMANCE

Directory of Open Access Journals (Sweden)

Ertugrul Gelen

2012-12-01

Full Text Available The purpose of this study was to compare the acute effects of static stretching; dynamic exercises and high volume upper extremity plyometric activity on tennis serve performance. Twenty-six elite young tennis players (15.1 ± 4.2 years, 167.9 ± 5.8 cm and 61.6 ± 8.1 kg performed 4 different warm-up (WU routines in a random order on non-consecutive days. The WU methods consisted of traditional WU (jogging, rally and serve practice (TRAD; traditional WU and static stretching (TRSS; traditional WU and dynamic exercise (TRDE; and traditional WU and high volume upper extremity plyometric activity (TRPLYP. Following each WU session, subjects were tested on a tennis serve ball speed test. TRAD, TRSS, TRDE and TRPLYO were compared by repeated measurement analyses of variance and post-hoc comparisons. In this study a 1 to 3 percent increase in tennis serve ball speed was recorded in TRDE and TRPLYO when compared to TRAD (p 0.05. ICCs for ball speed showed strong reliability (0.82 to 0.93 for the ball speed measurements.The results of this study indicate that dynamic and high volume upper extremity plyometric WU activities are likely beneficial to serve speed of elite junior tennis players.

High-Q Fabry–Pérot Micro-Cavities for High-Sensitivity Volume Refractometry

Directory of Open Access Journals (Sweden)

Noha Gaber

2018-01-01

Full Text Available This work reports a novel structure for a Fabry–Pérot micro cavity that combines the highest reported quality factor for an on-chip Fabry–Pérot resonator that exceeds 9800, and a very high sensitivity for an on-chip volume refractometer based on a Fabry–Pérot cavity that is about 1000 nm/refractive index unit (RIU. The structure consists of two cylindrical Bragg micromirrors that achieve confinement of the Gaussian beam in the plan parallel to the chip substrate, while for the perpendicular plan, external fiber rod lenses (FRLs are placed in the optical path of the input and the output of the cavity. This novel structure overcomes number of the drawbacks presented in previous designs. The analyte is passed between the mirrors, enabling its detection from the resonance peak wavelengths of the transmission spectra. Mixtures of ethanol and deionized (DI-water with different ratios are used as analytes with different refractive indices to exploit the device as a micro-opto-fluidic refractometer. The design criteria are detailed and the modeling is based on Gaussian-optics equations, which depicts a scenario closer to reality than the usually used ray-optics modeling.

Using electrochemical separation to reduce the volume of high-level nuclear waste

International Nuclear Information System (INIS)

Slater, S.A.; Gay, E.C.

1998-01-01

Argonne National Laboratory (ANL) has developed an electrochemical separation technique called electrorefining that will treat a variety of metallic spent nuclear fuel and reduce the volume of high-level nuclear waste that requires disposal. As part of that effort, ANL has developed a high throughput electrorefiner (HTER) that has a transport rate approximately three times faster than electrorefiners previously developed at ANL. This higher rate is due to the higher electrode surface area, a shorter transport path, and more efficient mixing, which leads to smaller boundary layers about the electrodes. This higher throughput makes electrorefining an attractive option in treating Department of Energy spent nuclear fuels. Experiments have been done to characterize the HTER, and a simulant metallic fuel has been successfully treated. The HTER design and experimental results is discussed

Modelling of high-enthalpy, high-Mach number flows

International Nuclear Information System (INIS)

Degrez, G; Lani, A; Panesi, M; Chazot, O; Deconinck, H

2009-01-01

A review is made of the computational models of high-enthalpy flows developed over the past few years at the von Karman Institute and Universite Libre de Bruxelles, for the modelling of high-enthalpy hypersonic (re-)entry flows. Both flows in local thermo-chemical equilibrium (LTE) and flows in thermo-chemical non-equilibrium (TCNEQ) are considered. First, the physico-chemical models are described, i.e. the set of conservation laws, the thermodynamics, transport phenomena and chemical kinetics models. Particular attention is given to the correct modelling of elemental (LTE flows) and species (chemical non-equilibrium-CNEQ-flows) transport. The numerical algorithm, based on a state-of-the-art finite volume discretization, is then briefly described. Finally, selected examples are included to illustrate the capabilities of the developed solver. (review article)

High-Flux Hemodialysis and High-Volume Hemodiafiltration Improve Serum Calcification Propensity.

Directory of Open Access Journals (Sweden)

Marijke Dekker

Full Text Available Calciprotein particles (CPPs may play an important role in the calcification process. The calcification propensity of serum (T50 is highly predictive of all-cause mortality in chronic kidney disease patients. Whether T50 is therapeutically improvable, by high-flux hemodialysis (HD or hemodiafiltration (HDF, has not been studied yet.We designed a cross-sectional single center study, and included stable prevalent in-center dialysis patients on HD or HDF. Patients were divided into two groups based on dialysis modality, were on a thrice-weekly schedule, had a dialysis vintage of > 3 months and vascular access providing a blood flow rate > 300 ml/min. Calcification propensity of serum was measured by the time of transformation from primary to secondary CPP (T50 test, by time-resolved nephelometry.We included 64 patients, mean convective volume was 21.7L (SD 3.3L. In the pooled analysis, T50 levels increased in both the HD and HDF group with pre- and post-dialysis (mean (SD of 244(64 - 301(57 and 253(55 - 304(61 min respectively (P = 0.43(HD vs. HDF. The mean increase in T50 was 26.29% for HD and 21.97% for HDF patients (P = 0.61 (HD vs. HDF. The delta values (Δ of calcium, phosphate and serum albumin were equal in both groups. Baseline T50 was negatively correlated with phosphate, and positively correlated with serum magnesium and fetuin-A. The ΔT50 was mostly influenced by Δ phosphate (r = -0.342; P = 0.002 HD and r = -0.396; P<0.001 HDF in both groups.HD and HDF patients present with same baseline T50 calcification propensity values pre-dialysis. Calcification propensity is significantly improved during both HD and HDF sessions without significant differences between both modalities.

High-speed volume measurement system

Energy Technology Data Exchange (ETDEWEB)

Lane, Michael H.; Doyle, Jr., James L.; Brinkman, Michael J.

2018-01-30

Disclosed is a volume sensor having a first axis, a second axis, and a third axis, each axis including a laser source configured to emit a beam; a parallel beam generating assembly configured to receive the beam and split the beam into a first parallel beam and a second parallel beam, a beam-collimating assembly configured to receive the first parallel beam and the second parallel beam and output a first beam sheet and a second beam sheet, the first beam sheet and the second beam sheet being configured to traverse the object aperture; a first collecting lens and a second collecting lens; and a first photodetector and a second photodetector, the first photodetector and the second photodetector configured to output an electrical signal proportional to the object; wherein the first axis, the second axis, and the third axis are arranged at an angular offset with respect to each other.

Current calibration, treatment, and treatment planning techniques among institutions participating in the Children's Oncology Group

International Nuclear Information System (INIS)

Urie, Marcia; FitzGerald, T.J.; Followill, David; Laurie, Fran; Marcus, Robert; Michalski, Jeff

2003-01-01

Purpose: To report current technology implementation, radiation therapy physics and treatment planning practices, and results of treatment planning exercises among 261 institutions belonging to the Children's Oncology Group (COG). Methods and Materials: The Radiation Therapy Committee of the newly formed COG mandated that each institution demonstrate basic physics and treatment planning abilities by satisfactorily completing a questionnaire and four treatment planning exercises designed by the Quality Assurance Review Center. The planning cases are (1) a maxillary sinus target volume (for two-dimensional planning), (2) a Hodgkin's disease mantle field (for irregular-field and off-axis dose calculations), (3) a central axis blocked case, and (4) a craniospinal irradiation case. The questionnaire and treatment plans were submitted (as of 1/30/02) by 243 institutions and completed satisfactorily by 233. Data from this questionnaire and analyses of the treatment plans with monitor unit calculations are presented. Results: Of the 243 clinics responding, 54% use multileaf collimators routinely, 94% use asymmetric jaws routinely, and 13% use dynamic wedges. Nearly all institutions calibrate their linear accelerators following American Association of Physicists in Medicine protocols, currently 16% with TG-51 and 81% with TG-21 protocol. Treatment planning systems are relied on very heavily for all calculations, including monitor units. Techniques and results of each of the treatment planning exercises are presented. Conclusions: Together, these data provide a unique compilation of current (2001) radiation therapy practices in institutions treating pediatric patients. Overall, the COG facilities have the equipment and the personnel to perform high-quality radiation therapy. With ongoing quality assurance review, radiation therapy compliance with COG protocols should be high

Cranial Tumor Surgical Outcomes at a High-Volume Academic Referral Center.

Science.gov (United States)

Brown, Desmond A; Himes, Benjamin T; Major, Brittny T; Mundell, Benjamin F; Kumar, Ravi; Kall, Bruce; Meyer, Fredric B; Link, Michael J; Pollock, Bruce E; Atkinson, John D; Van Gompel, Jamie J; Marsh, W Richard; Lanzino, Giuseppe; Bydon, Mohamad; Parney, Ian F

2018-01-01

To determine adverse event rates for adult cranial neuro-oncologic surgeries performed at a high-volume quaternary academic center and assess the impact of resident participation on perioperative complication rates. All adult patients undergoing neurosurgical intervention for an intracranial neoplastic lesion between January 1, 2009, and December 31, 2013, were included. Cases were categorized as biopsy, extra-axial/skull base, intra-axial, or transsphenoidal. Complications were categorized as neurologic, medical, wound, mortality, or none and compared for patients managed by a chief resident vs a consultant neurosurgeon. A total of 6277 neurosurgical procedures for intracranial neoplasms were performed. After excluding radiosurgical procedures and pediatric patients, 4151 adult patients who underwent 4423 procedures were available for analysis. Complications were infrequent, with overall rates of 9.8% (435 of 4423 procedures), 1.7% (73 of 4423), and 1.4% (63 of 4423) for neurologic, medical, and wound complications, respectively. The rate of perioperative mortality was 0.3% (14 of 4423 procedures). Case performance and management by a chief resident did not negatively impact outcome. In our large-volume brain tumor practice, rates of complications were low, and management of cases by chief residents in a semiautonomous manner did not negatively impact surgical outcomes. Copyright © 2017 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.

NATO Advanced Study Institute on Atoms in Strong Fields

CERN Document Server

Clark, Charles; Nayfeh, Munir

1990-01-01

This book collects the lectures given at the NATO Advanced Study Institute on "Atoms in Strong Fields", which took place on the island of Kos, Greece, during the two weeks of October 9-21,1988. The designation "strong field" applies here to an external electromagnetic field that is sufficiently strong to cause highly nonlinear alterations in atomic or molecular struc­ ture and dynamics. The specific topics treated in this volume fall into two general cater­ gories, which are those for which strong field effects can be studied in detail in terrestrial laboratories: the dynamics of excited states in static or quasi-static electric and magnetic fields; and the interaction of atoms and molecules with intense laser radiation. In both areas there exist promising opportunities for research of a fundamental nature. An electric field of even a few volts per centimeter can be very strong on the atom­ ic scale, if it acts upon a weakly bound state. The study of Rydberg states with high reso­ lution laser spectroscop...

Hospital volume and adverse events following esophageal endoscopic submucosal dissection in Japan.

Science.gov (United States)

Odagiri, Hiroyuki; Yasunaga, Hideo; Matsui, Hiroki; Matsui, Shigeru; Fushimi, Kiyohide; Kaise, Mitsuru

2017-04-01

Background and study aims  Esophageal endoscopic submucosal dissection (ESD) has gradually acquired popularity as a minimally invasive surgery for early cancers not only in Japan, but also in other countries. However, most reported outcomes have been based on relatively small samples of patients from specialized centers. Therefore, the association between hospital volume and the rate of adverse events following esophageal ESD has been poorly understood. Patients and methods  Using a nationwide administrative database in Japan, we identified patients who underwent esophageal ESD between 1 July 2007 and 31 March 2013. Hospital volume was defined as the number of esophageal ESD procedures performed per year at each hospital and was categorized into quartiles. Results  In total, 12 899 esophageal ESD procedures at 699 institutions were identified during the study period. Perforation and perforation-related disorders were observed in 422 patients (3.3 %), and one patient died after perforation. There was a significant association between a lower hospital volume and a higher proportion of adverse events following esophageal ESD. Although not statistically significant, a similar tendency was observed in the occurrence of blood transfusion within 1 week after ESD and all-cause in-hospital death. Multivariable logistic regression analysis showed that hospitals with very high case volumes were less likely to experience adverse events following esophageal ESD than hospitals with very low volumes. Conclusions  The proportion of perforation and perforation-related disorders following esophageal ESD was permissibly low, and there was a linear association between higher hospital volume and lower rates of adverse events following esophageal ESD. © Georg Thieme Verlag KG Stuttgart · New York.

High intensity and reduced volume training attenuates stress and recovery levels in elite swimmers

DEFF Research Database (Denmark)

Elbe, Anne-Marie; Rasmussen, Camilla P; Nielsen, Glen

2016-01-01

This study investigated the effect of increased high-intensity interval training (HIT) at the expense of total training volume on the stress and recovery levels of elite swimmers. Forty-one elite swimmers participated in the study and were randomly assigned to either a HIT or a control group (CON....... The Recovery Stress Questionnaire - Sport was used to measure the swimmers' stress and recovery levels. After the 12 week intervention, the general stress level was 16.6% (2.6-30.7%; mean and 95% CI) lower and the general recovery level was 6.5% (0.7-12.4%) higher in HIT compared to the CON, after adjusting...... for baseline values. No significant effects could be observed in sports-specific stress or sports-specific recovery. The results indicate that increasing training intensity and reducing training volume for 12 weeks can reduce general stress and increase general recovery levels in competitive swimmers....

Excluded volume effects caused by high concentration addition of acid generators in chemically amplified resists used for extreme ultraviolet lithography

Science.gov (United States)

Kozawa, Takahiro; Watanabe, Kyoko; Matsuoka, Kyoko; Yamamoto, Hiroki; Komuro, Yoshitaka; Kawana, Daisuke; Yamazaki, Akiyoshi

2017-08-01

The resolution of lithography used for the high-volume production of semiconductor devices has been improved to meet the market demands for highly integrated circuits. With the reduction in feature size, the molecular size becomes non-negligible in the resist material design. In this study, the excluded volume effects caused by adding high-concentration acid generators were investigated for triphenylsulfonium nonaflate. The resist film density was measured by X-ray diffractometry. The dependences of absorption coefficient and protected unit concentration on acid generator weight ratio were calculated from the measured film density. Using these values, the effects on the decomposition yield of acid generators, the protected unit fluctuation, and the line edge roughness (LER) were evaluated by simulation on the basis of sensitization and reaction mechanisms of chemically amplified extreme ultraviolet resists. The positive effects of the increase in acid generator weight ratio on LER were predominant below the acid generator weight ratio of 0.3, while the negative effects became equivalent to the positive effects above the acid generator weight ratio of 0.3 owing to the excluded volume effects.

Leading Contributors to the Research Consortium's Annual Program, 1992-2011: High-Visibility Institutions, Researchers, and Topics

Science.gov (United States)

Cardinal, Bradley J.; Lee, Hyo

2013-01-01

Between 1992-2011, peer-reviewed research on the Research Consortium's annual program has been published in abstract form in the "Research Quarterly for Exercise and Sport". On the basis of frequency, high-visibility institutions, researchers, and sub-disciplinary categories were identified. Data were extracted from each abstract (N =…

NATO Advanced Study Institute on Instabilities and Chaos in Quantum Optics

CERN Document Server

Arecchi, F; Lugiato, L; Instabilities and Chaos in Quantum Optics II

1988-01-01

This volume contains tutorial papers from the lectures and seminars presented at the NATO Advanced Study Institute on "Instabilities and Chaos in Quantum Optics", held at the "Il Ciocco" Conference Center, Castelvecchio Pascoli, Lucca, Italy, June 28-July 7, 1987. The title of the volume is designated Instabilities and Chaos in Quantum Optics II, because of the nearly coincident publication of a collection of articles on research in this field edited by F.T. Arecchi and R.G. Harrison [Instabilities and Chaos in Quantum Optics, (Springer, Berlin, 1987) 1. That volume provides more detailed information about some of these topics. Together they will serve as a comprehensive and tutorial pair of companion volumes. This school was directed by Prof. Massimo Inguscio, of the Department of Physics, University of Naples, Naples, Italy to whom we express our gratitude on behalf of all lecturers and students. The Scientific Advisory Committee consisted of N.B. Abraham of Bryn Mawr College; F.T. Arecchi of the National I...

High-resolution surface and volume-based in vivo atlas of the serotonin system in the healthy brain

DEFF Research Database (Denmark)

Beliveau, Vincent; Ganz, Melanie; Svarer, Claus

) was performed using the FS PET pipeline [7] with a Multilinear Reference Tissue Model 2 [8] for all tracers, using a high-binding region for estimating k2', with the exception of [18F]Altanserin for which steady-state quantification (BPP) was used. The individual BP maps were then averaged for each tracer...... to create the final maps. Results: Surface and volume-based average BPND and BPP maps were created for all tracers (Figures 1-4). The availability of structural MRI enabled us to perform accurate normalization in both surface and volume, a quality previously absent from similar work [9]. These maps...

ESTIMATION OF STAND HEIGHT AND FOREST VOLUME USING HIGH RESOLUTION STEREO PHOTOGRAPHY AND FOREST TYPE MAP

Directory of Open Access Journals (Sweden)

K. M. Kim

2016-06-01

Full Text Available Traditional field methods for measuring tree heights are often too costly and time consuming. An alternative remote sensing approach is to measure tree heights from digital stereo photographs which is more practical for forest managers and less expensive than LiDAR or synthetic aperture radar. This work proposes an estimation of stand height and forest volume(m3/ha using normalized digital surface model (nDSM from high resolution stereo photography (25cm resolution and forest type map. The study area was located in Mt. Maehwa model forest in Hong Chun-Gun, South Korea. The forest type map has four attributes such as major species, age class, DBH class and crown density class by stand. Overlapping aerial photos were taken in September 2013 and digital surface model (DSM was created by photogrammetric methods(aerial triangulation, digital image matching. Then, digital terrain model (DTM was created by filtering DSM and subtracted DTM from DSM pixel by pixel, resulting in nDSM which represents object heights (buildings, trees, etc.. Two independent variables from nDSM were used to estimate forest stand volume: crown density (% and stand height (m. First, crown density was calculated using canopy segmentation method considering live crown ratio. Next, stand height was produced by averaging individual tree heights in a stand using Esri’s ArcGIS and the USDA Forest Service’s FUSION software. Finally, stand volume was estimated and mapped using aerial photo stand volume equations by species which have two independent variables, crown density and stand height. South Korea has a historical imagery archive which can show forest change in 40 years of successful forest rehabilitation. For a future study, forest volume change map (1970s–present will be produced using this stand volume estimation method and a historical imagery archive.

Building a New South Africa Volume 1 : Economic Policy | IDRC ...

International Development Research Centre (IDRC) Digital Library (Canada)

Couverture du livre Building a New South Africa Volume 1 : Economic Policy. Editor(s): ... Findings from an IDRC-supported program figure prominently at the annual conference of McGill's Institute for the Study of International Development. ... Special journal issue highlights IDRC-supported findings on women's paid work.

Frontiers in pulse-power-based high energy density plasma physics and its applications

International Nuclear Information System (INIS)

Horioka, Kazuhiko

2008-03-01

The papers in this volume of report were presented at the Symposium on Frontiers in Pulse-power-based High Energy Density Physics' held by National Institute for Fusion Science. The topics include the present status of high energy density plasma researches, extreme ultraviolet sources, intense radiation sources, high power ion beams, and R and D of related pulse power technologies. The 13 of the presented papers are indexed individually. (J.P.N.)

Institutional Support : Institute of Statistical, Social and Economic ...

International Development Research Centre (IDRC) Digital Library (Canada)

The Institute of Statistical, Social and Economic Research (ISSER) established in 1969 is a semi-autonomous university-based research centre located at the University of Ghana, Legon, Accra. ISSER has a strong track record of undertaking high-quality policy-relevant research. This grant - the largest being awarded under ...

To what extent do long-duration high-volume dam releases influence river–aquifer interactions? A case study in New South Wales, Australia

KAUST Repository

Graham, Peter W.

2014-11-20

Long-duration high-volume dam releases are unique anthropogenic events with no naturally occurring equivalents. The impact from such dam releases on a downstream Quaternary alluvial aquifer in New South Wales, Australia, is assessed. It is observed that long-duration (>26 days), high-volume dam releases (>8,000 ML/day average) result in significant variations in river–aquifer interactions. These variations include a flux from the river to the aquifer up to 6.3 m3/day per metre of bank (at distances of up to 330 m from the river bank), increased extent and volume of recharge/bank storage, and a long-term (>100 days) reversal of river–aquifer fluxes. In contrast, during lower-volume events (<2,000 ML/day average) the flux was directed from the aquifer to the river at rates of up to 1.6 m3/day per metre of bank. A groundwater-head prediction model was constructed and river–aquifer fluxes were calculated; however, predicted fluxes from this method showed poor correlation to fluxes calculated using actual groundwater heads. Long-duration high-volume dam releases have the potential to skew estimates of long-term aquifer resources and detrimentally alter the chemical and physical properties of phreatic aquifers flanking the river. The findings have ramifications for improved integrated management of dam systems and downstream aquifers.

Nuclear legislation. Analytical study. Regulatory and Institutional framework for nuclear activities in OECD Member countries. Volume I

International Nuclear Information System (INIS)

1983-01-01

This study is part of a series of analytical studies of the major aspects of nuclear legislation in OECD Member countries and is published in two volumes. This Volume I of the study is a revision and an expansion of a 1969 study concerning the organisation and general regime governing nuclear activities. The national studies were prepared, to the extent possible, following a standard plan for all countries to facilitate information retrieval and comparison. (NEA) [fr

Influence of high volumes of ultra-fine additions on self-compacting concrete[ACI SP-239

Energy Technology Data Exchange (ETDEWEB)

Cioffi, R. [Naples Univ., Naples (Italy). Faculty of Engineering; Colangelo, F. [Naples Univ., Naples (Italy). Dept. of Technologies; Caputo, D.; Liguori, B. [Naples Univ., Naples (Italy). Dept. of Materials and Production Engineering

2006-07-01

The addition of fine minerals can reduce water demand and increase the slump characteristics of concrete. This paper examined the influence of high volumes of ultra-fine fly ash, raw fly ash, silica fume and natural zeolites on the properties of self-compacting concrete (SCC). Three samples of SCC were prepared using various mineral additions to determine normal slump and J-ring slump flows of fresh concrete as well as the compressive strength and elastic modulus properties of hardened concrete. Cement and crushed limestone natural aggregates were used. The fly ash, silica fume and natural zeolites were subjected to wet high energy milling. The rotating speed, milling time, water-to-solid ratio, and size of milling media were optimized to obtain powders with varying qualities. Results of the study showed that values for the normal slump flow ranged between 604 and 785 mm, while the differences with the J-ring slump flow were less than 30 mm. The samples were then tested to evaluate the mechanical properties of the hardened concrete after 7 and 28 curing days. The modulus of elasticity and compressive strength showed improvements in the concretes containing the ultra-fine fly ash. No segregation phenomena were observed in the case of the cylindrical column specimens. It was concluded that all the specimens provided environmentally sustainable, high workability concretes which can be successfully prepared with the addition of high volumes of minerals. 17 refs., 5 tabs., 6 figs.

Book Review: Lobbying the European Union: Institutions, Actors and Issues, David Coen and Jeremy Richardson (eds.

Directory of Open Access Journals (Sweden)

Alexandra Pop

2013-03-01

Full Text Available The volume "Lobbying the European Union: Institutions, Actors and Issues", collects 16 articles on interest group politics at EU level, focusing on the main elements of European lobbying - the existing relations between the EU institutions and the special interests, the main differences between NGO and business lobbying, the specific lobbying strategies adopted in EU's main policy sectors or lobbying regulations. The volume captures the main changes that took place on the European lobbying scene in the last two decades, period in which most EU institutions developed new points of access for lobbyists, while the interest groups became more specialized. The success of an EU lobbying campaign seems to be determined by a combination of various factors such as: a good knowledge of the EU environment, a wise usage of both financial resources and expertise, direct lobbying complemented by an efficient usage of domestic routes and the capability of creating smart alliances.

34. annual conference Ontario Petroleum Institute

International Nuclear Information System (INIS)

1995-01-01

A total of 18 papers, dealing with a variety of issues relevant to the petroleum industry, such as marketing strategies, feasibility studies and exploration technologies, were combined in this volume of proceedings of the 34th annual conference of the Ontario Petroleum Institute. Some of the papers presented case studies of hydrocarbon reserves in North America, along with their depositional histories. Oil yields and resource potential of fractured reservoirs was the subject of some presentations. Studies of cores from drilling sites and complete stratigraphic columns of some oil fields were also presented. (Papers are paged individually). refs., tabs., figs

Systems Sustainability: Implementation of Enhanced Maintenance Programs at the Kurchatov Institute, the All-Russian Research Institute of Experimental physics (VNIIEF) and the All-Russian Scientific Institute for Technical Physics (VNIITF)

International Nuclear Information System (INIS)

Coppinger, M.; Pikula, M.; Randolph, J.D.; Windham, M.

1999-01-01

Implementation of quality maintenance programs is essential to enhancing sustainable continuous operations of United States funded Materials Protection, Control and Accountability (MPC and A) equipment/systems upgrades at various Russian nuclear facilities. An effective maintenance program is expected to provide assurances to both parties for achieving maximum continuous systems operations with minimum down time. To be effective, the program developed must focus on minimum down time for any part of a system. Minimum down time is realized through the implementation of a quality maintenance program that includes preventative maintenance, necessary diagnostic tools, properly trained technical staff, and an in-house inventory of required spare parts for repairing the impacted component of the system. A centralized maintenance management program is logistically essential for the success of this effort because of the large volume of MPC and A equipment/systems installed at those sites. This paper will discuss current programs and conditions at the Russian Research Center-Kurchatov Institute, the All-Russian Scientific Institute for Technical Physics and the All-Russian Research Institute of Experimental Physics and will address those steps necessary to implement an upgraded program at those sites

Partial Molar Volume of Methanol in Water: Effect of Polarizability

Czech Academy of Sciences Publication Activity Database

Moučka, F.; Nezbeda, Ivo

2009-01-01

Roč. 74, č. 4 (2009), s. 559-563 ISSN 0010-0765 R&D Projects: GA AV ČR IAA400720802 Institutional research plan: CEZ:AV0Z40720504 Keywords : water–methanol mixtures * partial molar volume * polarizability Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 0.856, year: 2009

Paul Scherrer Institute Scientific Report 1998. Volume III: Condensed Matter Research with Neutrons

International Nuclear Information System (INIS)

Schefer, Juerg; Castellazzi, Denise; Bucher-Zimmermann, Claudia

1999-01-01

As a consequence of a major reorganisation at PSI, a new department has been formed with the groups focussing on research of condensed matter. The activities of the Laboratory of Neutron Scattering (jointly operated with the Swiss Federal Institute of Technology, ETH Zuerich), the Condensed Matter Theory Group, and the Group for Low Temperature Facilities, are described in this annual report

Organ donation in the ICU: A document analysis of institutional policies, protocols, and order sets.

Science.gov (United States)

Oczkowski, Simon J W; Centofanti, John E; Durepos, Pamela; Arseneau, Erika; Kelecevic, Julija; Cook, Deborah J; Meade, Maureen O

2018-04-01

To better understand how local policies influence organ donation rates. We conducted a document analysis of our ICU organ donation policies, protocols and order sets. We used a systematic search of our institution's policy library to identify documents related to organ donation. We used Mindnode software to create a publication timeline, basic statistics to describe document characteristics, and qualitative content analysis to extract document themes. Documents were retrieved from Hamilton Health Sciences, an academic hospital system with a high volume of organ donation, from database inception to October 2015. We retrieved 12 active organ donation documents, including six protocols, two policies, two order sets, and two unclassified documents, a majority (75%) after the introduction of donation after circulatory death in 2006. Four major themes emerged: organ donation process, quality of care, patient and family-centred care, and the role of the institution. These themes indicate areas where documented institutional standards may be beneficial. Further research is necessary to determine the relationship of local policies, protocols, and order sets to actual organ donation practices, and to identify barriers and facilitators to improving donation rates. Copyright © 2017 Elsevier Ltd. All rights reserved.

A new model for volume recombination in plane-parallel chambers in pulsed fields of high dose-per-pulse.

Science.gov (United States)

Gotz, M; Karsch, L; Pawelke, J

2017-11-01

In order to describe the volume recombination in a pulsed radiation field of high dose-per-pulse this study presents a numerical solution of a 1D transport model of the liberated charges in a plane-parallel ionization chamber. In addition, measurements were performed on an Advanced Markus ionization chamber in a pulsed electron beam to obtain suitable data to test the calculation. The experiment used radiation pulses of 4 μs duration and variable dose-per-pulse values up to about 1 Gy, as well as pulses of variable duration up to 308 [Formula: see text] at constant dose-per-pulse values between 85 mGy and 400 mGy. Those experimental data were compared to the developed numerical model and existing descriptions of volume recombination. At low collection voltages the observed dose-per-pulse dependence of volume recombination can be approximated by the existing theory using effective parameters. However, at high collection voltages large discrepancies are observed. The developed numerical model shows much better agreement with the observations and is able to replicate the observed behavior over the entire range of dose-per-pulse values and collection voltages. Using the developed numerical model, the differences between observation and existing theory are shown to be the result of a large fraction of the charge being collected as free electrons and the resultant distortion of the electric field inside the chamber. Furthermore, the numerical solution is able to calculate recombination losses for arbitrary pulse durations in good agreement with the experimental data, an aspect not covered by current theory. Overall, the presented numerical solution of the charge transport model should provide a more flexible tool to describe volume recombination for high dose-per-pulse values as well as for arbitrary pulse durations and repetition rates.

Feasibility of disposal of high-level radioactive waste into the seabed. Volume 1: Overview of research and conclusions

International Nuclear Information System (INIS)

1988-01-01

One of the options suggested for disposal of high-level radioactive waste resulting from the generation of nuclear power is burial beneath the deep ocean floor in geologically stable sediment formations which have no economic value. The 8-volume series provides an assessment of the technical feasibility and radiological safety of this disposal concept on the results obtained by ten years of co-operation and information exchange among the Member countries participating in the NEA Seabed Working Group. This volume provides an overview of the research and a summary of the results

Institutions, Anomie, and Violent Crime: Clarifying and Elaborating Institutional-Anomie Theory

Directory of Open Access Journals (Sweden)

Richard Rosenfeld

2008-11-01

Full Text Available A limited but accumulating body of research and theoretical commentary offers support for core claims of the “institutional-anomie theory” of crime (IAT and points to areas needing further development. In this paper, which focuses on violent crime, we clarify the concept of social institutions, elaborate the cultural component of IAT, derive implications for individual behavior, summarize empirical applications, and propose directions for future research. Drawing on Talcott Parsons, we distinguish the “subjective” and “objective” dimensions of institutional dynamics and discuss their interrelationship. We elaborate on the theory’s cultural component with reference to Durkheim’s distinction between “moral” and “egoistic” individualism and propose that a version of the egoistic type characterizes societies in which the economy dominates the institutional structure, anomie is rampant, and levels of violent crime are high. We also offer a heuristic model of IAT that integrates macro- and individual levels of analysis. Finally, we discuss briefly issues for the further theoretical elaboration of this macro-social perspective on violent crime. Specifically, we call attention to the important tasks of explaining the emergence of economic dominance in the institutional balance of power and of formulating an institutional account for distinctive punishment practices, such as the advent of mass incarceration in the United States.

Changes of the liver volume and the Child-Pugh score after high dose hypofractionated radiotherapy in patients with small hepatocellular carcinoma

International Nuclear Information System (INIS)

Kim, Young Il; Park, Hee Chul; Lim, Do Hoon; Park, Hyo Jung; Park, Su Yeon; Kim, Jin Sung; Han, Young Yih; Kang, Sang Won; Paik, Seung Woon

2012-01-01

To investigate the safety of high dose hypofractionated radiotherapy (RT) in patients with small hepatocellular carcinoma (HCC) in terms of liver volumetric changes and clinical liver function. We retrospectively reviewed 16 patients with small HCC who were treated with high dose hypofractionated RT between 2006 and 2009. The serial changes of the liver volumetric parameter were analyzed from pre-RT and follow-up (FU) computed tomography (CT) scans. We estimated linear time trends of whole liver volume using a linear mixed model. The serial changes of the Child-Pugh (CP) scores were also analyzed in relation to the volumetric changes. Mean pre-RT volume of entire liver was 1,192.2 mL (range, 502.6 to 1,310.2 mL) and mean clinical target volume was 14.7 mL (range, 1.56 to 70.07 mL). Fourteen (87.5%) patients had 4 FU CT sets and 2 (12.5%) patients had 3 FU CT sets. Mean interval between FU CT acquisition was 2.5 months. After considering age, gender and the irradiated liver volume as a fixed effects, the mixed model analysis confirmed that the change in liver volume is not significant throughout the time course of FU periods. Majority of patients had a CP score change less than 2 except in 1 patient who had CP score change more than 3. The high dose hypofractionated RT for small HCC is relatively safe and feasible in terms of liver volumetric changes and clinical liver function.

Fast and effective determination of strontium-90 in high volumes water samples

International Nuclear Information System (INIS)

Basarabova, B.; Dulanska, S.

2014-01-01

A simple and fast method was developed for determination of 90 Sr in high volumes of water samples from vicinity of nuclear power facilities. Samples were taken from the environment near Nuclear Power Plants in Jaslovske Bohunice and Mochovce in Slovakia. For determination of 90 Sr was used solid phase extraction using commercial sorbent Analig R Sr-01 from company IBC Advanced Technologies, Inc.. Determination of 90 Sr was performed with dilute solution of HNO 3 (1.5-2 M) and also tested in base medium with NaOH. For elution of 90 Sr was used eluent EDTA with pH in range 8-9. To achieve fast determination, automation was applied, which brings significant reduction of separation time. Concentration of water samples with evaporation was not necessary. Separation was performed immediately after filtration of analyzed samples. The aim of this study was development of less expensive, time unlimited and energy saving method for determination of 90 Sr in comparison with conventional methods. Separation time for fast-flow with volume of 10 dm 3 of water samples was 3.5 hours (flow-rate approximately 3.2 dm 3 / 1 hour). Radiochemical strontium yield was traced by using radionuclide 85 Sr. Samples were measured with HPGe detector (High-purity Germanium detector) at energy E φ = 514 keV. By using Analig R Sr-01 yields in range 72 - 96 % were achieved. Separation based on solid phase extraction using Analig R Sr-01 employing utilization of automation offers new, fast and effective method for determination of 90 Sr in water matrix. After ingrowth of yttrium samples were measured by Liquid Scintillation Spectrometer Packard Tricarb 2900 TR with software Quanta Smart. (authors)

Non-equilibrium Inertial Separation Array for High-throughput, Large-volume Blood Fractionation.

Science.gov (United States)

Mutlu, Baris R; Smith, Kyle C; Edd, Jon F; Nadar, Priyanka; Dlamini, Mcolisi; Kapur, Ravi; Toner, Mehmet

2017-08-30

Microfluidic blood processing is used in a range of applications from cancer therapeutics to infectious disease diagnostics. As these applications are being translated to clinical use, processing larger volumes of blood in shorter timescales with high-reliability and robustness is becoming a pressing need. In this work, we report a scaled, label-free cell separation mechanism called non-equilibrium inertial separation array (NISA). The NISA mechanism consists of an array of islands that exert a passive inertial lift force on proximate cells, thus enabling gentler manipulation of the cells without the need of physical contact. As the cells follow their size-based, deterministic path to their equilibrium positions, a preset fraction of the flow is siphoned to separate the smaller cells from the main flow. The NISA device was used to fractionate 400 mL of whole blood in less than 3 hours, and produce an ultrapure buffy coat (96.6% white blood cell yield, 0.0059% red blood cell carryover) by processing whole blood at 3 mL/min, or ∼300 million cells/second. This device presents a feasible alternative for fractionating blood for transfusion, cellular therapy and blood-based diagnostics, and could significantly improve the sensitivity of rare cell isolation devices by increasing the processed whole blood volume.

Large-volume heat storage tank made of GFK; Grosswaermespeichertank aus GFK

Energy Technology Data Exchange (ETDEWEB)

Buehl, J.; Schultheis, P. [Technische Univ. Ilmenau (Germany). Fachgebiet Technische Thermodynamik

1998-12-31

The Technical University of Ilmenau, the company Verbundwerkstoff- und Kunststoffanwendungstechnik Schoenbrunn, the Institute for Aerospace and Light-weight construction of Dresden University with its approved testing facilities for plastics and the Institute for Construction Engineering in Berlin and several other institutions co-operated since 1996 in developing a concept for a series of long-term heat storage tanks up to 6,000 cubic metres storage volume made of plastic (GFK components) with a combined thermal insulation. A model tank (sandwich body with proportional thermal insulation layer and selected mixed laminates) with a volume of 1.5 cubic metres was built and installed in November 1996. The tank has been continuously operated at various test levels. The experiment proves the longevity of the materials used. (orig.) [Deutsch] In Zusammenarbeit der TU Ilmenau mit der Fa. Verbundwerkstoff - und Kunststoffanwendungstechnik Schoenbrunn und dem Institut fuer Luftfahrttechnik und Leichtbau Dresden, seiner akkredierten Pruefstelle fuer Kunststoffe, in Abstimmung mit dem Institut fuer Bautechnik Berlin und weiteren Einrichtungen und Partnern wird seit 1996 an einem Konzept fuer eine Typenreihe Langzeitwaermespeicher bis vorerst 6.000 m{sup 3} Speichervolumen aus Kunststoff (GFK-Komponenten) und kombinierter integrierter thermischer Isolation gearbeitet. Im Vorfeld dieser Entwicklung wurde auf der Basis vorausgewaehlter Materialien und Kompositionen ein Musterspeicher (ein Sandwich - Modellkoerper mit proportionaler Waermedaemmschicht sowie ausgewaehlten Mischlaminaten) mit einem Speichervolumen von 1,5 m{sup 3} realisiert. Dieser Musterspeicher wurde im November 1996 installiert und wird seither kontinuierlich in den entsprechenden Erprobungsstufen betrieben. Der Nachweis der Langlebigkeit der eingesetzten Materialien wurde experimentell erbracht. (orig.)

Investigation of tDCS volume conduction effects in a highly realistic head model

Science.gov (United States)

Wagner, S.; Rampersad, S. M.; Aydin, Ü.; Vorwerk, J.; Oostendorp, T. F.; Neuling, T.; Herrmann, C. S.; Stegeman, D. F.; Wolters, C. H.

2014-02-01

Objective. We investigate volume conduction effects in transcranial direct current stimulation (tDCS) and present a guideline for efficient and yet accurate volume conductor modeling in tDCS using our newly-developed finite element (FE) approach. Approach. We developed a new, accurate and fast isoparametric FE approach for high-resolution geometry-adapted hexahedral meshes and tissue anisotropy. To attain a deeper insight into tDCS, we performed computer simulations, starting with a homogenized three-compartment head model and extending this step by step to a six-compartment anisotropic model. Main results. We are able to demonstrate important tDCS effects. First, we find channeling effects of the skin, the skull spongiosa and the cerebrospinal fluid compartments. Second, current vectors tend to be oriented towards the closest higher conducting region. Third, anisotropic WM conductivity causes current flow in directions more parallel to the WM fiber tracts. Fourth, the highest cortical current magnitudes are not only found close to the stimulation sites. Fifth, the median brain current density decreases with increasing distance from the electrodes. Significance. Our results allow us to formulate a guideline for volume conductor modeling in tDCS. We recommend to accurately model the major tissues between the stimulating electrodes and the target areas, while for efficient yet accurate modeling, an exact representation of other tissues is less important. Because for the low-frequency regime in electrophysiology the quasi-static approach is justified, our results should also be valid for at least low-frequency (e.g., below 100 Hz) transcranial alternating current stimulation.

Rheology and setting of high volume fly ash mixtures

Energy Technology Data Exchange (ETDEWEB)

Dale P. Bentz; Chiara F. Ferraris [National Institute of Standards and Technology, Gaithersburg, MD (United States). Building and Fire Research Laboratory

2010-04-15

While high volume fly ash (HVFA) concretes can be designed and produced to meet 28-d strength requirements and often even exceed the durability performance of conventional concretes, a persistent problem is the potentially long delay in setting time that produces concurrently long delays in finishing the concrete in the field. Previous isothermal calorimetry studies on two different powder additions, namely calcium hydroxide and a rapid set cement, have shown that these powders can mitigate excessive retardation of the hydration reactions. In this paper, rheological measurements and conventional Vicat setting time studies are conducted to verify that these powder additions do indeed reduce setting times in paste systems based on both ASTM Class C and ASTM Class F fly ashes. The reductions depend on the class of fly ash and suggest that trial mixtures would be a necessity to apply these technologies to each specific fly ash/cement/admixture combination being employed in the field. Potentially, for such screening studies, the rheological measurement of yield stress may provide a faster indication of setting (and finishability) than conventional Vicat needle penetration measurements on pastes.

Structural Aspects, Institutional Aspects, and Actors in the Organizational Field of Textbook Publishing : a case study on high school “Contemporary Society”

OpenAIRE

小原, 明恵

2016-01-01

The purpose of this paper is to clarify the organizational field of high school “Contemporary Society” textbook publishing using triadic relationship among structure, institutions, and actors as an analytical framework. Firstly, the Course of Study for high school “Contemporary Society” is explained as the institutional aspect of textbook publishing field. Secondly, the structural aspects of textbook publishing industry such as the market size, the number of publishers and textbooks, and the ...

Aperiodic Volume Optics

Science.gov (United States)

Gerke, Tim D.

Presented in this thesis is an investigation into aperiodic volume optical devices. The three main topics of research and discussion are the aperiodic volume optical devices that we call computer-generated volume holograms (CGVH), defects within periodic 3D photonic crystals, and non-periodic, but ordered 3D quasicrystals. The first of these devices, CGVHs, are designed and investigated numerically and experimentally. We study the performance of multi-layered amplitude computer-generated volume holograms in terms of efficiency and angular/frequency selectivity. Simulation results show that such aperiodic devices can increase diffraction efficiency relative to periodic amplitude volume holograms while maintaining angular and wavelength selectivity. CGVHs are also designed as voxelated volumes using a new projection optimization algorithm. They are investigated using a volumetric diffraction simulation and a standard 3D beam propagation technique as well as experimentally. Both simulation and experiment verify that the structures function according to their design. These represent the first diffractive structures that have the capacity for generating arbitrary transmission and reflection wave fronts and that provide the ability for multiplexing arbitrary functionality given different illumination conditions. Also investigated and discussed in this thesis are 3D photonic crystals and quasicrystals. We demonstrate that these devices can be fabricated using a femtosecond laser direct writing system that is particularly appropriate for fabrication of such arbitrary 3D structures. We also show that these devices can provide 3D partial bandgaps which could become complete bandgaps if fabricated using high index materials or by coating lower index materials with high index metals. Our fabrication method is particularly suited to the fabrication of engineered defects within the periodic or quasi-periodic systems. We demonstrate the potential for fabricating defects within

One hundred years at the intersection of chemistry and physics the Fritz Haber Institute of the Max Planck Society, 1911-2011

CERN Document Server

Hoffmann, Dieter; Steinhauser, Thomas; James, Jeremiah

2011-01-01

This volume, occasioned by the centenary of the Fritz Haber Institute, formerly the Institute for Physical Chemistry and Electrochemistry, covers the Institute's scientific and institutional history from its founding in 1911 as one the earliest institutes of the Kaiser Wilhelm Society, through its renaming for its founding director in 1952 and incorporation in the Max Planck Society, until the present. The Institute's pace-setting research in physical chemistry and chemical physics has been shaped by dozens of distinguished scientists, among them seven Nobel Laureates.

1997 Summer Research Program (SRP), High School Apprenticeship Program (HSAP), Final Reports, Volume 12B, Armstrong Laboratory

National Research Council Canada - National Science Library

Moore, Gary

1997-01-01

The United States Air Force Summer Research Program (USAF-SRP) is designed to introduce university, college, and technical institute faculty members, graduate students, and high school students to Air Force research...

6th International Conference on High Performance Scientific Computing

CERN Document Server

Phu, Hoang; Rannacher, Rolf; Schlöder, Johannes

2017-01-01

This proceedings volume highlights a selection of papers presented at the Sixth International Conference on High Performance Scientific Computing, which took place in Hanoi, Vietnam on March 16-20, 2015. The conference was jointly organized by the Heidelberg Institute of Theoretical Studies (HITS), the Institute of Mathematics of the Vietnam Academy of Science and Technology (VAST), the Interdisciplinary Center for Scientific Computing (IWR) at Heidelberg University, and the Vietnam Institute for Advanced Study in Mathematics, Ministry of Education The contributions cover a broad, interdisciplinary spectrum of scientific computing and showcase recent advances in theory, methods, and practical applications. Subjects covered numerical simulation, methods for optimization and control, parallel computing, and software development, as well as the applications of scientific computing in physics, mechanics, biomechanics and robotics, material science, hydrology, biotechnology, medicine, transport, scheduling, and in...

Volume and composition of emboli in neuroprotected stenting of the carotid artery.

Science.gov (United States)

Piñero, P; González, A; Martínez, E; Mayol, A; Rafel, E; González-Marcos, J R; Moniche, F; Cayuela, A; Gil-Peralta, A

2009-03-01

Periprocedural microembolization is a major and permanent risk for patients treated by angioplasty and stent placement of high-grade carotid stenoses. Little is known however about the characteristics and significance of these embolized particles. Our aim was to assess the volume and composition of debris captured by filters during carotid angioplasty and stent placement (CAS) of severe internal carotid artery (ICA) stenoses. Institutional review board approval and informed consent from all subjects were obtained. Two hundred one patients (mean age, 66.2 years; range, 35-82 years) with > or = 70% stenosis of the ICA underwent filter-protected CAS. Ultrastructural and semiquantitative analysis of the volume of filters was obtained. Multifactorial statistical analysis was performed to determine factors related to debris volume and composition. Transient ischemic attack occurred in 6 patients (3%), and a major stroke, in 1 (0.5%). Debris was found in 117 filters (58.2%), with volume <1 lambda (0.001 mL) in 71%. The number of balloon dilations, age older than 65 years, and calcified plaques in pre-CAS angiography were significantly associated with the presence of particulates inside the filters (P < .03, P < .004, and P < .05, respectively). Vessel wall and atheromatous plaques are the main source of microemboli during CAS. Embolization is mainly related to the number of balloon dilations during CAS. Planning a proper and individualized strategy for the procedure in each patient is essential to minimize the potential effects of manipulation during CAS.

Paul Scherrer Institute Scientific Report 1998. Volume III: Condensed Matter Research with Neutrons

Energy Technology Data Exchange (ETDEWEB)

Schefer, Juerg; Castellazzi, Denise; Bucher-Zimmermann, Claudia [eds.

1999-09-01

As a consequence of a major reorganisation at PSI, a new department has been formed with the groups focussing on research of condensed matter. The activities of the Laboratory of Neutron Scattering (jointly operated with the Swiss Federal Institute of Technology, ETH Zuerich), the Condensed Matter Theory Group, and the Group for Low Temperature Facilities, are described in this annual report figs., tabs., refs.

Middleware Proxy: A Request-Driven Messaging Broker For High Volume Data Distribution

CERN Document Server

Sliwinski, W; Dworak, A

2014-01-01

Nowadays, all major infrastructures and data centres (commercial and scientific) make an extensive use of the publish-subscribe messaging paradigm, which helps to decouple the message sender (publisher) from the message receiver (consumer). This paradigm is also heavily used in the CERN Accelerator Control system, in Proxy broker - critical part of the Controls Middleware (CMW) project. Proxy provides the aforementioned publish-subscribe facility and also supports execution of synchronous read and write operations. Moreover, it enables service scalability and dramatically reduces the network resources and overhead (CPU and memory) on publisher machine, required to serve all subscriptions. Proxy was developed in modern C++, using state of the art programming techniques (e.g. Boost) and following recommended software patterns for achieving low-latency and high concurrency. The outstanding performance of the Proxy infrastructure was confirmed during the last 3 years by delivering the high volume of LHC equipment...

Institutions, public debt and growth in Europe

Directory of Open Access Journals (Sweden)

Klaus Masuch

2017-06-01

Full Text Available This paper provides empirical evidence that supports the view that the quality of institutions is an important determinant of long-term growth in European countries. It shows that an initial high government debt level coupled with institutional quality below the EU average tends to be associated with particularly poor longterm real growth performance. Interestingly, the detrimental effect of high debt levels on long-term growth seems cushioned by the presence of very sound institutions. The paper offers some evidence that sound institutions may be particularly important for long-term growth in countries in which the exchange rate tool is no longer available and less so in countries with flexible exchange rate regimes. The empirical findings on the importance of institutions are robust to various measures of output growth, different measures of institutional indicators, different sample sizes, different country groupings and to the inclusions of additional control variables.

High-dose preoperative chemoradiotherapy in esophageal cancer patients does not increase postoperative pulmonary complications: Correlation with dose-volume histogram parameters

International Nuclear Information System (INIS)

Hurmuzlu, Meysan; Ovrebo, Kjell; Wentzel-Larsen, Tore; Muren, Ludvig Paul; Viste, Asgaut; Smaaland, Rune

2010-01-01

Purpose: To investigate the association of high-dose preoperative chemoradiotherapy (CRT) and dose-volume histogram (DVH) parameters of lungs with incidence of postoperative pulmonary complications and to identify predictive clinical factors of pulmonary complications. Methods: Data of 65 patients were collected retrospectively. Thirty-five patients underwent transthoracic esophagectomy (TTE) alone and 30 received cisplatin and 5-fluorouracil, concomitant with radiotherapy, median dose 66 Gy, and followed by TTE. From the DVH for each lung alone and for both lungs together as one organ we generated total lung volume, mean radiotherapy dose, relative and absolute volumes receiving more than a threshold dose, and relative and absolute volumes receiving less than a threshold dose. Postoperative pulmonary complications were defined as pneumonia or respiratory failure. Results: Sixty percent of the patients in the TTE alone group had postoperative pulmonary complications versus 63% in the CRT + TTE group. Postoperative mortality was 8.6% and 16.7% in the respective patient groups (p = NS). None of the DVH parameters was associated with postoperative pulmonary complications. Squamous cell carcinoma was an adverse factor related to increased postoperative pulmonary complications. Conclusion: High-dose preoperative CRT was not associated with increased postoperative pulmonary complications in this cohort of esophageal cancer patients.

Quantifying volume loss from ice cliffs on debris-covered glaciers using high-resolution terrestrial and aerial photogrammetry

NARCIS (Netherlands)

Brun, Fanny; Buri, Pascal; Miles, Evan S.; Wagnon, Patrick; Steiner, J.F.; Berthier, Etienne; Ragettli, S.; Kraaijenbrink, P.D.A.; Immerzeel, W.W.; Pellicciotti, Francesca

Mass losses originating from supraglacial ice cliffs at the lower tongues of debris-covered glaciers are a potentially large component of the mass balance, but have rarely been quantified. In this study, we develop a method to estimate ice cliff volume losses based on high-resolution topographic

Pozzolanic Activity Assessment of LUSI (LUmpur SIdoarjo) Mud in Semi High Volume Pozzolanic Mortar

Science.gov (United States)

Hardjito, Djwantoro; Antoni; Wibowo, Gunadi M.; Christianto, Danny

2012-01-01

LUSI mud obtained from the mud volcano in Sidoarjo, Indonesia, is a viable aluminosilicate material to be utilized as pozzolanic material. LUSI is an abbreviation of the local name of the mud, i.e., Lumpur Sidoarjo, meaning Sidoarjo mud. This paper reports the results of an investigation to assess the pozzolanic activity of LUSI mud, especially in semi high volume pozzolanic mortar. In this case, the amount of mud incorporated is between 30% to 40% of total cementitious material, by mass. The content of SiO2 in the mud is about 30%, whilst the total content of SiO2, Fe2O3 and Al2O3 is more than 70%. Particle size and degree of partial cement replacement by treated LUSI mud affect the compressive strength, the strength activity index (SAI), the rate of pozzolanic activity development, and the workability of mortar incorporating LUSI mud. Manufacturing semi high volume LUSI mud mortar, up to at least 40% cement replacement, is a possibility, especially with a smaller particle size of LUSI mud, less than 63 μm. The use of a larger percentage of cement replacement by LUSI mud does not show any adverse effect on the water demand, as the flow of the fresh mortar increased with the increase of percentage of LUSI mud usage.

A Japanese prospective multi-institutional feasibility study on accelerated partial breast irradiation using interstitial brachytherapy: treatment planning and quality assurance

International Nuclear Information System (INIS)

Otani, Yuki; Nose, Takayuki; Dokiya, Takushi; Saeki, Toshiaki; Kumazaki, Yu

2015-01-01

In Japan, breast-conserving surgery with closed cavity has generally been performed for breast cancer patients, and accelerated partial breast irradiation (APBI) is considered difficult because Asian females generally have smaller breast sizes than Western females. Therefore, common identification of target and treatment plan method in APBI is required. A prospective multicenter study was conducted in Japan to determine institutional compliance with APBI using high-dose-rate interstitial brachytherapy (ISBT) designed for Japanese female patients. For this study, 46 patients were recruited at eight institutions from January 2009 to December 2011. The reproducibility of the ISBT–APBI plan was evaluated using three criteria: (1) minimum clinical target volume dose with a clip dose ≥ 6 Gy/fraction, (2) irradiated volume constraint of 40-150 cm 3 , and (3) uniformity of dose distribution, expressed as the dose non-uniformity ratio (DNR, V150/V100) < 0.35. The ISBT–APBI plan for each patient was considered reproducible when all three criteria were met. When the number of non-reproducible patients was ≤ 4 at study completion, APBI at this institution was considered statistically reproducible. Half of the patients (52 %) had a small bra size (A/B cup). The mean values of the dose-constrained parameters were as follows: Vref, 117 cm 3 (range, 40-282), DNR, 0.30 (range, 0.22-0.51), and clip dose, 784 cGy (range, 469-3146). A total of 43/46 treatment plans were judged to be compliant and ISBT–APBI was concluded to be reproducible. This study showed that multi-institutional ISBT–APBI treatment plan was reproducible for small breast patient with closed cavity

TTI Phase 2 Institutional Support: Sustainable Development Policy ...

International Development Research Centre (IDRC) Digital Library (Canada)

TTI Phase 2 Institutional Support: Sustainable Development Policy Institute. This funding will strengthen the Sustainable Development Policy Institute's (SDPI) role as a credible public policy institution in Pakistan by enhancing its ability to provide high-quality, influential, and policy-relevant research. About the Sustainable ...

Comparison of different volumes of high intensity interval training on cardiac autonomic function in sedentary young women.

Science.gov (United States)

Bhati, Pooja; Bansal, Vishal; Moiz, Jamal Ali

2017-08-24

Purpose The present study was conducted to compare the effects of low volume of high intensity interval training (LVHIIT) and high volume of high intensity interval training (HVHIIT) on heart rate variability (HRV) as a primary outcome measure, and on maximum oxygen consumption (VO2max), body composition, and lower limb muscle strength as secondary outcome measures, in sedentary young women. Methods Thirty-six participants were recruited in this study. The LVHIIT group (n = 17) performed one 4-min bout of treadmill running at 85%-95% maximum heart rate (HRmax), followed by 3 min of recovery by running at 70% HRmax, three times per week for 6 weeks. The HVHIIT group (n = 15) performed four times 4-min bouts of treadmill running at 85%-95% HRmax, interspersed with 3-min of recovery by running at 70% HRmax, 3 times per week for 6 weeks. All criterion measures were measured before and after training in both the groups. Results Due to attrition of four cases, data of 32 participants was used for analysis. A significant increase in high frequency (HF) power (p high frequency power (LF/HF) ratio (p body composition, and muscle strength. Conclusion The study results suggest that both LVHIIT and HVHIIT are equally effective in improving VO2max, body composition, and muscle strength, in sedentary young women. However, HVHIIT induces parasympathetic dominance as well, as measured by HRV.

Small-Volume Injections: Evaluation of Volume Administration Deviation From Intended Injection Volumes.

Science.gov (United States)

Muffly, Matthew K; Chen, Michael I; Claure, Rebecca E; Drover, David R; Efron, Bradley; Fitch, William L; Hammer, Gregory B

2017-10-01

In the perioperative period, anesthesiologists and postanesthesia care unit (PACU) nurses routinely prepare and administer small-volume IV injections, yet the accuracy of delivered medication volumes in this setting has not been described. In this ex vivo study, we sought to characterize the degree to which small-volume injections (≤0.5 mL) deviated from the intended injection volumes among a group of pediatric anesthesiologists and pediatric postanesthesia care unit (PACU) nurses. We hypothesized that as the intended injection volumes decreased, the deviation from those intended injection volumes would increase. Ten attending pediatric anesthesiologists and 10 pediatric PACU nurses each performed a series of 10 injections into a simulated patient IV setup. Practitioners used separate 1-mL tuberculin syringes with removable 18-gauge needles (Becton-Dickinson & Company, Franklin Lakes, NJ) to aspirate 5 different volumes (0.025, 0.05, 0.1, 0.25, and 0.5 mL) of 0.25 mM Lucifer Yellow (LY) fluorescent dye constituted in saline (Sigma Aldrich, St. Louis, MO) from a rubber-stoppered vial. Each participant then injected the specified volume of LY fluorescent dye via a 3-way stopcock into IV tubing with free-flowing 0.9% sodium chloride (10 mL/min). The injected volume of LY fluorescent dye and 0.9% sodium chloride then drained into a collection vial for laboratory analysis. Microplate fluorescence wavelength detection (Infinite M1000; Tecan, Mannedorf, Switzerland) was used to measure the fluorescence of the collected fluid. Administered injection volumes were calculated based on the fluorescence of the collected fluid using a calibration curve of known LY volumes and associated fluorescence.To determine whether deviation of the administered volumes from the intended injection volumes increased at lower injection volumes, we compared the proportional injection volume error (loge [administered volume/intended volume]) for each of the 5 injection volumes using a linear

Snow cover volumes dynamic monitoring during melting season using high topographic accuracy approach for a Lebanese high plateau witness sinkhole

Science.gov (United States)

Abou Chakra, Charbel; Somma, Janine; Elali, Taha; Drapeau, Laurent

2017-04-01

Climate change and its negative impact on water resource is well described. For countries like Lebanon, undergoing major population's rise and already decreasing precipitations issues, effective water resources management is crucial. Their continuous and systematic monitoring overs long period of time is therefore an important activity to investigate drought risk scenarios for the Lebanese territory. Snow cover on Lebanese mountains is the most important water resources reserve. Consequently, systematic observation of snow cover dynamic plays a major role in order to support hydrologic research with accurate data on snow cover volumes over the melting season. For the last 20 years few studies have been conducted for Lebanese snow cover. They were focusing on estimating the snow cover surface using remote sensing and terrestrial measurement without obtaining accurate maps for the sampled locations. Indeed, estimations of both snow cover area and volumes are difficult due to snow accumulation very high variability and Lebanese mountains chains slopes topographic heterogeneity. Therefore, the snow cover relief measurement in its three-dimensional aspect and its Digital Elevation Model computation is essential to estimate snow cover volume. Despite the need to cover the all lebanese territory, we favored experimental terrestrial topographic site approaches due to high resolution satellite imagery cost, its limited accessibility and its acquisition restrictions. It is also most challenging to modelise snow cover at national scale. We therefore, selected a representative witness sinkhole located at Ouyoun el Siman to undertake systematic and continuous observations based on topographic approach using a total station. After four years of continuous observations, we acknowledged the relation between snow melt rate, date of total melting and neighboring springs discharges. Consequently, we are able to forecast, early in the season, dates of total snowmelt and springs low

Measuring the volume of temporal lobe in healthy Chinese adults of the Han nationality on the high-resolution MRI

International Nuclear Information System (INIS)

Jia Kefeng; Wu Li; Duan Hui; Han Dan; Chen Nan; Li Kuncheng

2010-01-01

Objective: To explore the morphological features of temporal lobe of healthy Chinese Han adults on the high-resolution MRI and provide morphological data of temporal lobe for the construction of database for Chinese Standard Brain. Methods: This is a clinical multi-center study. Three hundred healthy Chinese volunteers (male 150, and female 150) recruited from 15 hospitals were divided equally into five groups according to their age, i.e., 18-30 (Group A), 31-40 (Group B), 41-50 (Group C), 51- 60(Group D), 61-70(Group E). All subjects were scanned using T 1 WI 3D MPRAGE sequence and volumes of standardized temporal lobe were collected. The bilateral volumes of standardized temporal lobe were compared by variance analysis between male and female subjects and among five age groups. Results: The mean volumes of left and right temporal lobe were (97 126±15 703) mm 3 and (97 015 ± 15 545) mm 3 respectively for men, and (95 123 ± 14 564) mm 3 and (96 423 ± 13 407) mm 3 for women. The difference temporal lobe volume between male and female wasn't significant on the same side (F=1.336, 0.127, P= 0.249, 0.722). The left temporal lobe volumes of Group A-E were (93 873±13 351), (95 566± 11 964), (10 1890 ± 14 511), (93 972 ± 14 050) and (95 636 ± 19 864) mm 3 respectively, and those on the right side were (93 409 ± 10 984), (98 158 ± 16 392), (102 079 ± 15 112), (95 448 ± 11 123) and (94 658 ± 16 928) mm 3 . There were significant differences among 5 groups between left and right temporal lobe volume(F=2.940, 3.514, P=0.021, 0.008). Further pairwise comparison revealed that left and right temporal lobe volume in Group C is higher than those of Group A and D (P 0.05). Conclusion: High-resolution MRI could offer detailed images and precise morphological data of temporal lobe, which provides morphological data of temporal lobe for the construction of database for Chinese Standard Brain. (authors)

Feasibility of disposal of high-level radioactive waste into the seabed. Volume 4: Engineering

International Nuclear Information System (INIS)

Hickerson, J.; Freeman, T.J.; Boisson, J.Y.; Murray, C.N.; Gera, F.; Nakamura, H.; Nieuwenhuis, J.D.; Schaller, K.H.

1988-01-01

One of the options suggested for disposal of high-level radioactive waste resulting from the generation of nuclear power is burial beneath the deep ocean floor in geologically stable sediment formations which have no economic value. The 8-volume series provides an assessment of the technical feasibility and radiological safety of this disposal concept based on the results obtained by ten years of co-operation and information exchange among the Member countries participating in the NEA Seabed Working Group. This report summarizes work performed to develop and evaluate engineering methods of emplacing high level radioactive waste in stable, deep ocean sediments. It includes results of desktop studies, laboratory experiments and field tests conducted in deep water

Natural gas annual 1992: Volume 1

Energy Technology Data Exchange (ETDEWEB)

1993-11-22

This document provides information on the supply and disposition of natural gas to a wide audience including industry, consumers, Federal and State agencies, and education institutions. The 1992 data are presented in a sequence that follows natural gas (including supplemental supplies) from its production top its end use. Tables summarizing natural gas supply and disposition from 1988 to 1992 are given for each Census Division and each State. Annual historical data are shown at the national level. Volume 2 of this report presents State-level historical data.

The proposed EROSpace institute, a national center operated by space grant universities

Science.gov (United States)

Smith, Paul L.; Swiden, LaDell R.; Waltz, Frederick A.

1993-01-01

The "EROSpace Institute" is a proposed visiting scientist program in associated with the U.S. Geological Survey's EROS Data Center (EDC). The Institute would be operated by a consortium of universities, possible drawn from NASA's Space Grant College and Fellowship Program consortia and the group of 17 capability-enhancement consortia, or perhaps from consortia though out the nation with a topical interest in remote sensing. The National Center for Atmospheric Research or the Goddard Institute for Space Studies provide models for the structure of such an institute. The objectives of the Institute are to provide ready access to the body of data housed at the EDC and to increase the cadre of knowledgeable and trained scientists able to deal with the increasing volume of remote sensing data to become available from the Earth Observing System. The Institute would have a staff of about 100 scientists at any one time, about half permanent staff, and half visiting scientists. The latter would include graduate and undergraduate students, as well as faculty on temporary visits, summer fellowships, or sabbatical leaves. The Institute would provide office and computing facilities, as well as Internet linkages to the home institutions so that scientists could continue to participate in the program from their home base.

Performance Assessment Institute-NV

Energy Technology Data Exchange (ETDEWEB)

Lombardo, Joesph [Univ. of Nevada, Las Vegas, NV (United States)

2012-12-31

The National Supercomputing Center for Energy and the Environment’s intention is to purchase a multi-purpose computer cluster in support of the Performance Assessment Institute (PA Institute). The PA Institute will serve as a research consortium located in Las Vegas Nevada with membership that includes: national laboratories, universities, industry partners, and domestic and international governments. This center will provide a one-of-a-kind centralized facility for the accumulation of information for use by Institutions of Higher Learning, the U.S. Government, and Regulatory Agencies and approved users. This initiative will enhance and extend High Performance Computing (HPC) resources in Nevada to support critical national and international needs in "scientific confirmation". The PA Institute will be promoted as the leading Modeling, Learning and Research Center worldwide. The program proposes to utilize the existing supercomputing capabilities and alliances of the University of Nevada Las Vegas as a base, and to extend these resource and capabilities through a collaborative relationship with its membership. The PA Institute will provide an academic setting for interactive sharing, learning, mentoring and monitoring of multi-disciplinary performance assessment and performance confirmation information. The role of the PA Institute is to facilitate research, knowledge-increase, and knowledge-sharing among users.

Novel reprocessing methods with nuclide separation for volume reduction of high level radioactive waste

International Nuclear Information System (INIS)

Suzuki, Tatsuya

2015-01-01

We have proposed the reprocessing system with nuclide separation processes based on the chromatographic technique in the hydrochloric acid solution system. Our proposing system consists of the dissolution process, the reprocessing process, the MA separation process, and nuclide separation processes. In our proposing processes, the pyridine resin is used as a main separation media. We expect that our proposing will contribute to that volume reduction of high level radioactive waste by combining the transmutation techniques, usage of valuable elements, and so on. (author)

Volume of high-risk intratumoral subregions at multi-parametric MR imaging predicts overall survival and complements molecular analysis of glioblastoma

Energy Technology Data Exchange (ETDEWEB)

Cui, Yi; Li, Ruijiang [Stanford University, Department of Radiation Oncology, Palo Alto, CA (United States); Hokkaido University, Global Station for Quantum Medical Science and Engineering, Global Institution for Collaborative Research and Education, Hokkaido (Japan); Ren, Shangjie [Tianjin University, School of Electrical Engineering and Automation, Tianjin Shi (China); Tha, Khin Khin; Shirato, Hiroki [Hokkaido University, Global Station for Quantum Medical Science and Engineering, Global Institution for Collaborative Research and Education, Hokkaido (Japan); Hokkaido University, Department of Radiology and Nuclear Medicine, Hokkaido (Japan); Wu, Jia [Stanford University, Department of Radiation Oncology, Palo Alto, CA (United States)

2017-09-15

To develop and validate a volume-based, quantitative imaging marker by integrating multi-parametric MR images for predicting glioblastoma survival, and to investigate its relationship and synergy with molecular characteristics. We retrospectively analysed 108 patients with primary glioblastoma. The discovery cohort consisted of 62 patients from the cancer genome atlas (TCGA). Another 46 patients comprising 30 from TCGA and 16 internally were used for independent validation. Based on integrated analyses of T1-weighted contrast-enhanced (T1-c) and diffusion-weighted MR images, we identified an intratumoral subregion with both high T1-c and low ADC, and accordingly defined a high-risk volume (HRV). We evaluated its prognostic value and biological significance with genomic data. On both discovery and validation cohorts, HRV predicted overall survival (OS) (concordance index: 0.642 and 0.653, P < 0.001 and P = 0.038, respectively). HRV stratified patients within the proneural molecular subtype (log-rank P = 0.040, hazard ratio = 2.787). We observed different OS among patients depending on their MGMT methylation status and HRV (log-rank P = 0.011). Patients with unmethylated MGMT and high HRV had significantly shorter survival (median survival: 9.3 vs. 18.4 months, log-rank P = 0.002). Volume of the high-risk intratumoral subregion identified on multi-parametric MRI predicts glioblastoma survival, and may provide complementary value to genomic information. (orig.)

EUV source development for high-volume chip manufacturing tools

Science.gov (United States)

Stamm, Uwe; Yoshioka, Masaki; Kleinschmidt, Jürgen; Ziener, Christian; Schriever, Guido; Schürmann, Max C.; Hergenhan, Guido; Borisov, Vladimir M.

2007-03-01

Xenon-fueled gas discharge produced plasma (DPP) sources were integrated into Micro Exposure Tools already in 2004. Operation of these tools in a research environment gave early learning for the development of EUV sources for Alpha and Beta-Tools. Further experiments with these sources were performed for basic understanding on EUV source technology and limits, especially the achievable power and reliability. The intermediate focus power of Alpha-Tool sources under development is measured to values above 10 W. Debris mitigation schemes were successfully integrated into the sources leading to reasonable collector mirror lifetimes with target of 10 billion pulses due to the effective debris flux reduction. Source collector mirrors, which withstand the radiation and temperature load of Xenon-fueled sources, have been developed in cooperation with MediaLario Technologies to support intermediate focus power well above 10 W. To fulfill the requirements for High Volume chip Manufacturing (HVM) applications, a new concept for HVM EUV sources with higher efficiency has been developed at XTREME technologies. The discharge produced plasma (DPP) source concept combines the use of rotating disk electrodes (RDE) with laser exited droplet targets. The source concept is called laser assisted droplet RDE source. The fuel of these sources has been selected to be Tin. The conversion efficiency achieved with the laser assisted droplet RDE source is 2-3x higher compared to Xenon. Very high pulse energies well above 200 mJ / 2π sr have been measured with first prototypes of the laser assisted droplet RDE source. If it is possible to maintain these high pulse energies at higher repetition rates a 10 kHz EUV source could deliver 2000 W / 2π sr. According to the first experimental data the new concept is expected to be scalable to an intermediate focus power on the 300 W level.

Hippocampus and amygdala volumes in children and young adults at high-risk of schizophrenia: research synthesis.

Science.gov (United States)

Ganzola, Rossana; Maziade, Michel; Duchesne, Simon

2014-06-01

Studies have reported hippocampal and amygdala volume abnormalities in schizophrenic patients. It is necessary to explore the potential for these structures as early disease markers in subjects at high risk (HR) of schizophrenia. We performed a review of 29 magnetic resonance imaging (MRI) studies measuring hippocampal and amygdala volumes in subjects at HR for schizophrenia. We reclassified subjects in 3 new HR categories: presence of only risk symptoms (psychotic moderate symptoms), presence of only risk factors (genetic, developmental or environmental), and presence of combined risk symptoms/factors. Hippocampal volume reductions were detected in subjects with first episode (FE) of psychosis, in all young adults and in adolescents at HR of schizophrenia. The loss of tissue was mainly located in the posterior part of hippocampus and the right side seems more vulnerable in young adults with only risk symptoms. Instead, the anterior sector seems more involved in HR subjects with genetic risks. Abnormal amygdala volumes were found in FE subjects, in children with combined risk symptoms/factors and in older subjects using different inclusion criteria, but not in young adults. Hippocampal and amygdala abnormalities may be present before schizophrenia onset. Further studies should be conducted to clarify whether these abnormalities are causally or effectually related to neurodevelopment. Shape analysis could clarify the impact of environmental, genetic, and developmental factors on the medial temporal structures during the evolution of this disease. Copyright © 2014 Elsevier B.V. All rights reserved.

Provider volume and outcomes for oncological procedures.

LENUS (Irish Health Repository)

Killeen, S D

2012-02-03

BACKGROUND: Oncological procedures may have better outcomes if performed by high-volume providers. METHODS: A review of the English language literature incorporating searches of the Medline, Embase and Cochrane collaboration databases was performed. Studies were included if they involved a patient cohort from 1984 onwards, were community or population based, and assessed health outcome as a dependent variable and volume as an independent variable. The studies were also scored quantifiably to assess generalizability with respect to any observed volume-outcome relationship and analysed according to organ system; numbers needed to treat were estimated where possible. RESULTS: Sixty-eight relevant studies were identified and a total of 41 were included, of which 13 were based on clinical data. All showed either an inverse relationship, of variable magnitude, between provider volume and mortality, or no volume-outcome effect. All but two clinical reports revealed a statistically significant positive relationship between volume and outcome; none demonstrated the opposite. CONCLUSION: High-volume providers have a significantly better outcome for complex cancer surgery, specifically for pancreatectomy, oesphagectomy, gastrectomy and rectal resection.

Volume of the crocodilian brain and endocast during ontogeny

Czech Academy of Sciences Publication Activity Database

Jirák, D.; Janáček, Jiří

2017-01-01

Roč. 12, č. 6 (2017), č. článku e0178491. E-ISSN 1932-6203 R&D Projects: GA ČR(CZ) GAP302/12/1207; GA ČR(CZ) GA13-12412S Institutional support: RVO:67985823 Keywords : brain volume * endoneurocranium * crocodilians * magnetic resonance imaging Subject RIV: EA - Cell Biology OBOR OECD: Developmental biology Impact factor: 2.806, year: 2016

High frequency oscillatory ventilation with lung volume optimization in very low birth weight newborns – a nine-year experience

Directory of Open Access Journals (Sweden)

José Nona

2009-09-01

Full Text Available Objective: To evaluate the clinical outcome of very low birth weight newborns, submitted to high frequency oscillatory ventilation with a strategy of early lung volume optimization. Methods: Descriptive prospective study in a nine-year period, between 1999 January 1st to 2008 January 1st. All the very low birth weight newborns were born in Dr. Alfredo da Costa Maternity, Lisbon, Portugal, were admitted to the Neonatal Intensive Care Unit and submitted to high frequency oscillatory ventilation with early lung volume optimization; these newborns were followed-up since birth and their charts were analyzed periodically until hospital discharge. Rresults: From a total population of 730 very low birth weight inborns, 117 babies died (16% and 613 survived (84%. The median of birth weight was 975 g and the gestational age median was 28 weeks. For the survivors, the median ventilation and oxygenation times were 3 and 18 days, respectively. The incidence of chronic lung disease was 9.5%, with nine newborns discharged on oxygen therapy. The incidence of intraventricular hemorrhage III – IV (total population group was 11.5% and the incidence of retinopathy of prematurity grade 3 or higher was 8.0%. Cconclusions: High frequency oscillatory ventilation with early lung volume optimization strategy reduced the need of respiratory support, and improved pulmonary and global outcomes in very low birth weight infants with respiratory distress syndrome.

Determination of radionuclide concentrations in ground level air using the ASS-500 high volume sampler

International Nuclear Information System (INIS)

Frenzel, E.; Arnold, D.; Wershofen, H.

1996-01-01

A method for determination of radionuclide concentrations in air aerosol samples collected by the high volume aerosol sampler ASS-500 was elaborated. The aerosol sampling station ASS-500 is a Stand alone, all-weather proofed instrument. It is designed for representative sampling of airborne radionuclides from ground level air at a height of about 1.5 m above ground level. The ASS-500 station enables continuous air monitoring both normal and emergency Situations. The collection of aerosols on the Petrianov FPP-15-1.5 type filter out of an air volume of about 100,000 m 3 (sampling period 1 wk) or of about 250,000 m 3 (sampling period 3 wk) admits accurate spectrometric low level measurements of natural and artificial radionuclides. The achieved detection limit is 0.5 μBq m -3 and 0.2 μBq m -3 for 137 Cs, respectively. A new developed air flow Meter system allows to enhance the collected air volume to about 150,000 m 3 per week and lowers the detection limit to -3 for 137 Cs for weekly collected aerosol samples. In Poland the CLOR uses 9 Stations ASS-500 at different sites as atmospheric radioactivity control system. On the basis of spectrometric measurements of natural and artificial radionuclides in the collected aerosol samples at the different sites, CLOR establishes a weekly report about the radiological situation at Poland for responsible authorities. The very low achievable detection limit of the Station ASS-500 due 10 the high air flow fate and the long possible sampling period were the key argument for other government radiation protection authorities in Europe to introduce the Station ASS-500 into their low level radionuclide atmospheric monitoring programs (Austria, Belarus, France, Germany, Iceland, Spain, Switzerland, Ukraine)

Market development study for active solar thermal systems in the institutional, commercial and industrial sectors : final report

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-03-01

Promising market opportunities for the sale of Active Solar Thermal Systems (ASTS) in the institutional, commercial and industrial sectors of the Canadian economy were examined in an effort to identify the main factors for success and the barriers to development of the ASTS market. This report described some of the action plans which could help Natural Resources Canada and the industry to develop these markets. It was noted that a promising ASTS application should have a substantial market. Some of the promising applications for ASTS include air heating applications such as: (1) make-up air to an industrial facility, particularly one that requires a high rate of air flow or air layer destratification, such as in welding operations, paint shops or vehicle maintenance facilities, (2) ventilation to a high-walled commercial or institutional building that requires high air flow such as in schools, recreational facilities, multi-residential or retail buildings, and (3) slow drying applications for crops, lumber or other materials. Promising water heating applications include: (1) high volume low temperature rise applications such as in swimming pools, (2) domestic hot water to high density accommodations such as in hotels, multi-unit dwellings, college residences and military barracks, (3) domestic hot water to an isolated location such as campgrounds or lodges, and (4) process hot water used for water washing in industry, restaurants, farms and car washes. This study concluded that there are many opportunities for sales of ASTS to the institutional, commercial and industrial sectors, but combined efforts are needed by committed members of the community to take advantage of these opportunities. 15 refs., 11 tabs., 2 figs., 4 append.

Multiphase volume-preserving interface motions via localized signed distance vector scheme

Czech Academy of Sciences Publication Activity Database

Muhammad, R. Z.; Švadlenka, Karel

2015-01-01

Roč. 8, č. 5 (2015), s. 969-988 ISSN 1937-1632 Institutional support: RVO:67985840 Keywords : multiphase mean curvature flow * vector-valued signed distance * volume preservation Subject RIV: BA - General Mathematics Impact factor: 0.737, year: 2015 http://www.aimsciences.org/journals/displayArticlesnew.jsp?paperID=11386

Uranium milling, project M-25. Volume I. summary and text. Final generic environmental impact statement

International Nuclear Information System (INIS)

1980-09-01

The Final Generic Environmental Impact Statement (GEIS) on Uranium Milling focuses primarily upon the matter of mill tailings disposal. It evaluates both the costs and benefits of alternative tailings disposal modes and draws conclusions about criteria which should be incorporated into regulations. Both institutional and technical controls are evaluated. Health impacts considered were both short and long term. Restatement and resolution of all public comments received on the draft (GEIS) are presented. There are three volumes: Volume I is the main text and Volumes II and III are supporting appendices

Assessment of interpatient heterogeneity in tumor radiosensitivity for nonsmall cell lung cancer using tumor-volume variation data

Energy Technology Data Exchange (ETDEWEB)

Chvetsov, Alexei V., E-mail: chvetsov2@gmail.com; Schwartz, Jeffrey L.; Mayr, Nina [Department of Radiation Oncology, University of Washington, 1959 NE Pacific Street, Seattle, Washington 98195-6043 (United States); Yartsev, Slav [London Regional Cancer Program, London Health Sciences Centre, 790 Commissioners Road East, London, Ontario 46A 4L6 (Canada)

2014-06-15

Purpose: In our previous work, the authors showed that a distribution of cell surviving fractionsS{sub 2} in a heterogeneous group of patients could be derived from tumor-volume variation curves during radiotherapy for head and neck cancer. In this research study, the authors show that this algorithm can be applied to other tumors, specifically in nonsmall cell lung cancer. This new application includes larger patient volumes and includes comparison of data sets obtained at independent institutions. Methods: Our analysis was based on two data sets of tumor-volume variation curves for heterogeneous groups of 17 patients treated for nonsmall cell lung cancer with conventional dose fractionation. The data sets were obtained previously at two independent institutions by using megavoltage computed tomography. Statistical distributions of cell surviving fractionsS{sub 2} and clearance half-lives of lethally damaged cells T{sub 1/2} have been reconstructed in each patient group by using a version of the two-level cell population model of tumor response and a simulated annealing algorithm. The reconstructed statistical distributions of the cell surviving fractions have been compared to the distributions measured using predictive assays in vitro. Results: Nonsmall cell lung cancer presents certain difficulties for modeling surviving fractions using tumor-volume variation curves because of relatively large fractional hypoxic volume, low gradient of tumor-volume response, and possible uncertainties due to breathing motion. Despite these difficulties, cell surviving fractionsS{sub 2} for nonsmall cell lung cancer derived from tumor-volume variation measured at different institutions have similar probability density functions (PDFs) with mean values of 0.30 and 0.43 and standard deviations of 0.13 and 0.18, respectively. The PDFs for cell surviving fractions S{sub 2} reconstructed from tumor volume variation agree with the PDF measured in vitro. Conclusions: The data obtained

Rowing increases stroke volume and cardiac output to a greater extent than cycling

Czech Academy of Sciences Publication Activity Database

Horn, P.; Ošťádal, P.; Ošťádal, Bohuslav

2015-01-01

Roč. 64, č. 2 (2015), s. 203-207 ISSN 0862-8408 Institutional support: RVO:67985823 Keywords : cardiac output * cycling * heart rate * stroke volume Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery Impact factor: 1.643, year: 2015

77 FR 28281 - Withdrawal of Revocation of TSCA Section 4 Testing Requirements for One High Production Volume...

Science.gov (United States)

2012-05-14

... Withdrawal of Revocation of TSCA Section 4 Testing Requirements for One High Production Volume Chemical...]amino]- (CAS No. 1324-76-1), also known as C.I. Pigment Blue 61. EPA received an adverse comment regarding C.I. Pigment Blue 61. This document withdraws the revocation of testing requirements for C.I...

Measuring the volume of insula in healthy Chinese adults of the Han nationality on the high-resolution MRI

International Nuclear Information System (INIS)

Qi Guangrui; Guo Yulin; Lai Yanbo; Gong Rui; Zhu Kai; Zhao Dan; Chen Nan; Wang Xing; Li Kuncheng; Zhuo Yan; Chen Lin

2010-01-01

volume (F= -0.361, -0.337, P 3 , the right were (8694 ± 1005), (8136 ± 1100), (8034 ± 910), (7496 ± 990), (6989 ± 932) mm 3 , there were significant differences among 5 groups between left and right insula volume (F= -0.490, -0.512, P<0.01). There was significant negative correlation between the volume and age( before standarizded: r= -0.361, -0.337, after standardized r=-0.490, -0.512, P<0.05). Before and after standardized, there was significant correlation between the volume of right and left insula and cerebral volume (r=0.470,0.459, P<0.05). Before and after standardized, there was significant correlation between the volume of right and left insula and weight(r =0.141,0.092,P<0.05). Conclusions: 1.5 T MR scanner has high resolution, for distinguishing the white matter from the gray matter, and provide morphological data of insula for the construction of database for Chinese Standard Brain. (authors)

[Target volume margins for lung cancer: internal target volume/clinical target volume].

Science.gov (United States)

Jouin, A; Pourel, N

2013-10-01

The aim of this study was to carry out a review of margins that should be used for the delineation of target volumes in lung cancer, with a focus on margins from gross tumour volume (GTV) to clinical target volume (CTV) and internal target volume (ITV) delineation. Our review was based on a PubMed literature search with, as a cornerstone, the 2010 European Organisation for Research and Treatment of Cancer (EORTC) recommandations by De Ruysscher et al. The keywords used for the search were: radiotherapy, lung cancer, clinical target volume, internal target volume. The relevant information was categorized under the following headings: gross tumour volume definition (GTV), CTV-GTV margin (first tumoural CTV then nodal CTV definition), in field versus elective nodal irradiation, metabolic imaging role through the input of the PET scanner for tumour target volume and limitations of PET-CT imaging for nodal target volume definition, postoperative radiotherapy target volume definition, delineation of target volumes after induction chemotherapy; then the internal target volume is specified as well as tumoural mobility for lung cancer and respiratory gating techniques. Finally, a chapter is dedicated to planning target volume definition and another to small cell lung cancer. For each heading, the most relevant and recent clinical trials and publications are mentioned. Copyright © 2013. Published by Elsevier SAS.

Institutional path dependence and environmental water recovery in Australia’s Murray-Darling Basin

Directory of Open Access Journals (Sweden)

Graham R. Marshall

2016-10-01

Full Text Available The concept of institutional path dependence offers useful ways of understanding the trajectories of water policy reforms and how past institutional arrangements, policy paradigms and development patterns constrain current and future choices and limit institutional adaptability. The value of this concept is demonstrated through an analysis of environmental water recovery in Australia’s Murray-Darling Basin, where while significant water volumes have been reallocated to the environment, the costs have also been significant. While there are significant lessons from the Australian experience, attempts to emulate the approach involve substantive risks and may be prohibitively costly for less wealthy nations. Context-specific institutional analysis is emphasised as fundamental to water reform and critical for reform architecture and sequencing. A key finding is that while crisis can provide powerful catalysts for institutional innovation, institutional path dependence in the absence of active and disruptive policy entrepreneurs fosters a strong tendency to reinforce the status quo and limit innovation, potentially exposing social-ecological systems to greater shocks due to climate change and other sources of escalating uncertainty.

Growth Curve Models and Applications : Indian Statistical Institute

CERN Document Server

2017-01-01

Growth curve models in longitudinal studies are widely used to model population size, body height, biomass, fungal growth, and other variables in the biological sciences, but these statistical methods for modeling growth curves and analyzing longitudinal data also extend to general statistics, economics, public health, demographics, epidemiology, SQC, sociology, nano-biotechnology, fluid mechanics, and other applied areas.   There is no one-size-fits-all approach to growth measurement. The selected papers in this volume build on presentations from the GCM workshop held at the Indian Statistical Institute, Giridih, on March 28-29, 2016. They represent recent trends in GCM research on different subject areas, both theoretical and applied. This book includes tools and possibilities for further work through new techniques and modification of existing ones. The volume includes original studies, theoretical findings and case studies from a wide range of app lied work, and these contributions have been externally r...

Comparison of T2 and FLAIR imaging for target delineation in high grade gliomas

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Miller Robert W

2010-01-01

Full Text Available Abstract Background FLAIR and T2 weighted MRIs are used based on institutional preference to delineate high grade gliomas and surrounding edema for radiation treatment planning. Although these sequences have inherent physical differences there is limited data on the clinical and dosimetric impact of using either or both sequences. Methods 40 patients with high grade gliomas consecutively treated between 2002 and 2008 of which 32 had pretreatment MRIs with T1, T2 and FLAIR available for review were selected for this study. These MRIs were fused with the treatment planning CT. Normal structures, clinical tumor volume (CTV and planning tumor volume (PTV were then defined on the T2 and FLAIR sequences. A Venn diagram analysis was performed for each pair of tumor volumes as well as a fractional component analysis to assess the contribution of each sequence to the union volume. For each patient the tumor volumes were compared in terms of total volume in cubic centimeters as well as anatomic location using a discordance index. The overlap of the tumor volumes with critical structures was calculated as a measure of predicted toxicity. For patients with MRI documented failures, the tumor volumes obtained using the different sequences were compared with the recurrent gross tumor volume (rGTV. Results The FLAIR CTVs and PTVs were significantly larger than the T2 CTVs and PTVs (p Conclusions Although both T2 and FLAIR MRI sequences are used to define high grade glial neoplasm and surrounding edema, our results show that the volumes generated using these techniques are different and not interchangeable. These differences have bearing on the use of intensity modulated radiation therapy (IMRT and highly conformal treatment as well as on future clinical trials where the bias of using one technique over the other may influence the study outcome.

High-Efficiency Volume Reflection of an Ultrarelativistic Proton Beam with a Bent Silicon Crystal

CERN Document Server

Scandale, Walter; Carnera, Alberto; Della Mea, Gianantonio; De Salvador, Davide; Milan, Riccardo; Vomiero, Alberto; Baricordi, Stefano; Dalpiaz, Pietro; Fiorini, Massimiliano; Guidi, Vincenzo; Martinelli,Giuliano; Mazzolari, Andrea; Milan, Emiliano; Ambrosi, Giovanni; Azzarello, Philipp; Battiston, Roberto; Bertucci, Bruna; Burger, William J; Ionica, Maria; Zuccon, Paolo; Cavoto, Gianluca; Santacesaria, Roberta; Valente, Paolo; Vallazza, Erik; Afonin, Alexander G; Baranov, Vladimir T; Chesnokov, Yury A; Kotov, Vladilen I; Maisheev, Vladimir A; Yaznin, Igor A; Afansiev, Sergey V; Kovalenko, Alexander D; Taratin, Alexander M; Denisov, Alexander S; Gavrikov, Yury A; Ivanov, Yuri M; Ivochkin, Vladimir G; Kosyanenko, Sergey V; Petrunin, Anatoli A; Skorobogatov, Vyacheslav V; Suvorov, Vsevolod M; Bolognini, Davide; Foggetta,Luca; Hasan, Said; Prest, Michela

2007-01-01

The volume reflection phenomenon was detected while investigating 400 GeV proton interactions with bent silicon crystals in the external beam H8 of the CERN Super Proton Synchrotron. Such a process was observed for a wide interval of crystal orientations relative to the beam axis, and its efficiency exceeds 95%, thereby surpassing any previously observed value. These observations suggest new perspectives for the manipulation of high-energy beams, e.g., for collimation and extraction in new-generation hadron colliders, such as the CERN Large Hadron Collider.

Sustainability in Canadian Post-Secondary Institutions: The Interrelationships among Sustainability Initiatives and Geographic and Institutional Characteristics

Science.gov (United States)

Beveridge, Dan; McKenzie, Marcia; Vaughter, Philip; Wright, Tarah

2015-01-01

Purpose: This paper aims to report on a census of high-level sustainability initiatives at all accredited post-secondary institutions in Canada by documenting the institutions that have undertaken sustainability assessments, have signed one or more sustainability declarations, have sustainability offices or officers or have sustainability…

Influence of Utilization of High-Volumes of Class F Fly Ash on the Abrasion Resistance of Concrete

Directory of Open Access Journals (Sweden)

William PRINCE

2007-01-01

Full Text Available Utilization of large volumes of fly ash in various concrete applications is a becoming a more general practice in an efforts towards using large quantities of fly ash. Around the world, Class C or Class F or both as available have been used in high volumes in cement-based materials. In India, majority of fly generated is of Class F type as per ASTM C 618. Yearly fly ash generation in India is approximately 95 million tonnes. Out of which around 15-20% is utilized in cement production and cement/concrete related activities. In order to increase its percentage utilization, an investigation was carried out to use it in concrete.In this paper, abrasion resistance of high volume fly ash (HVFA concretes made with 35, 45, 55, and 65% of cement replacement was evaluated in terms of its relation with compressive strength. Comparison was made between ordinary Portland cement and fly ash concrete. Test results indicated that abrasion resistance of concrete having cement replacement up to 35 percent was comparable to the normal concrete mix with out fly ash. Beyond 35% cement replacement, fly ash concretes exhibited slightly lower resistance to abrasion relative to non-fly ash concretes. Test results further indicated that abrasion resistance of concrete is closely related with compressive strength, and had a very good correlation between abrasion resistance and compressive strength (R2 value between 0.9018 and 0.9859 depending upon age.

Measuring the volume of caudate nucleus in healthy Chinese adults of the Han nationality on the high-resolution MRI

International Nuclear Information System (INIS)

Ni Mingfei; Chen Nan; Wang Xing; Wu Jianlin; Li Kuncheng; Zhou Xin; Zhou Yan; Chen Lin

2010-01-01

Objective: To explore the normal range of the caudate nucleus' volume in Chinese adults of the Han nationality and provide morphological data for the construction of database for Chinese Standard Brain. Methods: This was a clinical multi-center study. One thousand Chinese healthy volunteers (age range =18 to 70) recruited from 16 hospitals were divided into 5 groups, i.e, Group A (age range = 18 to 30), B (age range =31 to 40), C (age range =41 to 50), D (age range =51 to 60), and E (age range =61 to 70). Each group contained 100 males and 100 females. All of the volunteers were scanned by MR using T 1 weighted three-dimensional magnetization prepared rapid acquisition gradient echo sequence. The volume of caudate was measured manually using 3D volume analysis software. The difference of volumes of the caudate between male and female were analyzed by independent sample t-test, and among age groups by ANOVA. Pearson's correlation coefficient was used to characterize the relationship between volumes and age. The differences of measurements between left and right caudate nucleus were analyzed by paired t test. Results: (1) The mean volume of bilateral caudate nucleus in healthy Chinese adults was (10.973± 1.647) cm 3 . The mean volume of the the male's left and right caudate nucleus were (5.656±0.860) and (5.671±0.855) cm 3 respectively,no significant differences were found between the volume of left and right caudate nucleus (t=1.230, P>0.05). The mean volume of the the female's left and right caudate nucleus were (5.287±0.774) and (5.331±0.766) cm 3 respectively, and the right's was larger than the left's with significant differences (t=3.999, P<0.01); (2) Pearson correlation analysis showed a significant negative correlation between the nucleus volume and age (male and female's, left and right) (r=-0.561, -0.568, -0.548, -0.552, P<0.05). Conclusion: With high-resolution MRI and 3D volumetric analytic software (Midob), the volume of the caudate nucleus can be

Estimation of mean tree stand volume using high-resolution aerial RGB imagery and digital surface model, obtained from sUAV and Trestima mobile application

Directory of Open Access Journals (Sweden)

G. K. Rybakov

2017-06-01

Full Text Available This study considers a remote sensing technique for mean volume estimation based on a very high-resolution (VHR aerial RGB imagery obtained using a small-sized unmanned aerial vehicle (sUAV and a high-resolution photogrammetric digital surface model (DSM as well as an innovative technology for field measurements (Trestima. The study area covers approx. 220 ha of forestland in Finland. The work concerns the entire process from remote sensing and field data acquisition to statistical analysis and forest volume wall-to-wall mapping. The study showed that the VHR aerial imagery and the high-resolution DSM produced based on the application of the sUAV have good prospects for forest inventory. For the sUAV based estimation of forest variables such as Height, Basal Area and mean Volume, Root Mean Square Error constituted 6.6 %, 22.6 % and 26.7 %, respectively. Application of Trestima for estimation of the mean volume of the standing forest showed minor difference over the existing Forest Management Plan at all the selected forest compartments. Simultaneously, the results of the study confirmed that the technologies and the tools applied at this work could be a reliable and potentially cost-effective means of forest data acquisition with high potential of operational use.

NATO Advanced Study Institute on Physics of New Laser Sources

CERN Document Server

Arecchi, F; Mooradian, Aram; Sona, Alberto

1985-01-01

This volume contains the lectures and seminars presented at the NATO Advanced Study Institute on "Physics of New Laser Sources", the twelfth course of the Europhysics School of Quantum Electronics, held under the supervision of the Quantum Electronics Division of the European Physical Society. The Institute was held at Centro "I Cappuccini" San Miniato, Tuscany, July 11-21, 1984. The Europhysics School of Quantum Electronics was started in 1970 with the aim of providing instruction for young researchers and advanced students already engaged in the area of quantum electronics or for those wishing to switch into this area after working previously in other areas. From the outset, the School has been under the direction of Prof. F. T. Arecchi, then at the University of Pavia, now at the University of Florence, and Dr. D. Roess of Heraeus, Hanau. In 1981, Prof. H. Walther, University of Munich and Max-Planck Institut fur Quantenoptik joined as co-director. Each year the Directors choose a subj~ct of particular int...

Impact of Case Volume on Outcomes of Ureteroscopy for Ureteral Stones

DEFF Research Database (Denmark)

Kandasami, Sangam V; Mamoulakis, Charalampos; El-Nahas, Ahmed R

2014-01-01

of case volume on the outcomes of URS for ureteral stones. DESIGN, SETTING, AND PARTICIPANTS: The URS Global Study collected prospective data on consecutive patients with urinary stones treated with URS at 114 centres worldwide for 1 yr. Centres were identified as low or high volume based on the median...... overall annual case volume. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Pre- and intraoperative characteristics, and postoperative outcomes in patients at low- and high-volume centres were compared. The relationships between case volume and stone-free rate (SFR), stone burden, complications...... SFR was 91.9% and 86.3% at high- and low-volume centres, respectively (pstone-free outcome increased with increasing case volume (p

Polarized training has greater impact on key endurance variables than threshold, high intensity or high volume training

Directory of Open Access Journals (Sweden)

Thomas eStöggl

2014-02-01

Full Text Available Endurance athletes integrate four conditioning concepts in their training programs: high-volume training (HVT, ‘threshold-training’ (THR, high-intensity interval training (HIIT and a combination of these aforementioned concepts known as polarized training (POL. The purpose of this study was to explore which of these four training concepts provides the greatest response on key components of endurance performance in well-trained endurance athletes. Methods: Forty eight runners, cyclists, triathletes and cross-country skiers (peak oxygen uptake: (VO2peak: 62.6±7.1 mL∙min-1∙kg-1 were randomly assigned to one of four groups performing over nine weeks. An incremental test, work economy and a VO2peak tests were performed. Training intensity was heart rate controlled. Results: POL demonstrated the greatest increase in VO2peak (+6.8 ml∙min∙kg-1 or 11.7%, P0.05. Conclusion: POL resulted in the greatest improvements in most key variables of endurance performance in well-trained endurance athletes. THR or HVT did not lead to further improvements in performance related variables.

High concentration tritium gas measurement with small volume ionization chambers for fusion fuel gas monitors

International Nuclear Information System (INIS)

Uda, Tatsuhiko; Okuno, Kenji; Matsuda, Yuji; Naruse, Yuji

1991-01-01

To apply ionization chambers to fusion fuel gas processing systems, high concentration tritium gas was experimentally measured with small volume 0.16 and 21.6 cm 3 ionization chambers. From plateau curves, the optimum electric field strength was obtained as 100∼200 V/cm. Detection efficiency was confirmed as dependent on the ionization ability of the filled gas, and moreover on its stopping power, because when the range of the β-rays was shortened, the probability of energy loss by collisions with the electrode and chamber wall increased. Loss of ions by recombination was prevented by using a small volume ionization chamber. For example the 0.16 cm 3 ionization chamber gave measurement with linearity to above 40% tritium gas. After the tritium gas measurements, the concentration levels inside the chamber were estimated from their memory currents. Although more than 1/4,000 of the maximum, current was observed as a memory effect, the smaller ionization chamber gave a smaller memory effect. (author)

Strategic planning for clinical services: the University of Texas M.D. Anderson Hospital and Tumor Institute.

Science.gov (United States)

Anderson, R W

1986-09-01

A formal, hospitalwide strategic-planning process provides structure for the pharmacy's plans for implementing clinical services. The state-supported clinical cancer and research center began a formal strategic-planning process in 1981. The institution's planning report, prepared every two years and covering three two-year periods, drives the institution's budget through the state's biennial budget process. The report focuses on each department's responsibilities, areas of service, and relationship to the mission of the institution. Through the long-range planning process, upper-level administrators learned that pharmacy was eager not only to provide high-volume drug distribution services but also to assume direct patient-care and research responsibilities. This prompted an organizational change for pharmacy from a hospital department to a clinical division. The division of pharmacy now consists of three professional departments (patient care, pharmacy research, and pharmacy academic programs) and an administrative support service area. Services offered by each of the three departments are discussed, along with specific initiatives planned for the years 1987-1993. Within the next few years, all managers will come from the ranks of clinical practitioners; nonpharmacists will oversee financial and human resource functions. The division encourages existing pharmacy staff members to enhance their clinical skills through staff development programs. Strategic planning serves the dual purposes of structuring plans for implementing clinical pharmacy services and communicating pharmacy's goals within the institution.

Short-term moderate intensive high volume training program provides aerobic endurance benefit in wheelchair basketball players.

Science.gov (United States)

Skucas, Kestutis; Pokvytyte, Vaida

2017-04-01

The aim of this paper was to investigate the effect of short-term period, moderate intensity and high volume endurance training on physiological variables in elite wheelchair basketball players. Eight wheelchair basketball players were examined. The subjects participated in a two-week intervention program of mainly two training types: wheelchair basketball and wheelchair driving endurance training. The subjects performed the continuously increasing cycling exercise (CCE) at the constant 60 rpm arm cranking speed at the beginning of the program and after two weeks of the program. The initial workload was 20 W, then the workload was increased by 2 W every 5 seconds until fatigue. The post training of the wheelchair basketball group in the study showed a significant improvement in the peak oxygen uptake (VO2peak) and the peak power output (POpeak). VO2peak increased by 9% from 2.32±0.16 L/min to 2.53±0.2 L/min (Pbasketball squad had relatively high levels of aerobic fitness prior to participating in the endurance training program. Nevertheless, the high-volume, moderate-intensity, short-term training program, which evolved over the two-weeks period, resulted in the improvement of the athlete's aerobic endurance. The ventilatory threshold (VT) and the second ventilatory threshold (VT2) are good markers for aerobic capacity of wheelchair athletes.

Intenational conference on high-energy physics. Volume 2. Sessions IV to VIII. [Geneva, June 27-July 4, 1979

Energy Technology Data Exchange (ETDEWEB)

1980-02-01

Volume 2 of the conference proceedings contains sessions on hadron physics, charged-lepton physics, the p-p-bar collider at CERN, future European accelerator possibilities, parallel discussion sessions (on high-energy) hadron-induced reactions, deep inelastic phenomena, hadron spectroscopy, weak ineractions and gauge theories, and quark confinement), and a closing session on gauge appreciation of developments in particle physics. A list of participants is also included. Three of the papers in this volume have already been cited in ERA, and can be found as reference to the entry CONF-790642-- in the Report Number Index. The remaining 36 will be processed as they are received on the Atomindex tape. (RWR)

Exploring the relation between process design and efficiency in high-volume cataract pathways from a lean thinking perspective

NARCIS (Netherlands)

van Vliet, Ellen J.; Bredenhoff, E.; Bredenhoff, Eelco; Sermeus, Walter; Kop, Lucas M.; Sol, Johannes C.A.; van Harten, Willem H.

2011-01-01

Objective: To compare process designs of three high-volume cataract pathways in a lean thinking framework and to explore how efficiency in terms of lead times, hospital visits and costs is related to process design. Design: International retrospective comparative benchmark study with a mixed-method

Endoscopic surgery versus conservative treatment for the moderate-volume hematoma in spontaneous basal ganglia hemorrhage (ECMOH: study protocol for a randomized controlled trial

Directory of Open Access Journals (Sweden)

Zan Xin

2012-06-01

Full Text Available Abstract Background Spontaneous intracerebral hemorrhage is a disease with high morbidity, high disability rate, high mortality, and high economic burden. Whether patients can benefit from surgical evacuation of hematomas is still controversial, especially for those with moderate-volume hematomas in the basal ganglia. This study is designed to compare the efficacy of endoscopic surgery and conservative treatment for the moderate-volume hematoma in spontaneous basal ganglia hemorrhage. Methods Patients meet the criteria will be randomized into the endoscopic surgery group (endoscopic surgery for hematoma evacuation and the best medical treatment or the conservative treatment group (the best medical treatment. Patients will be followed up at 1, 3, and 6 months after initial treatment. The primary outcomes include the Extended Glasgow Outcome Scale and the Modified Rankin Scale. The secondary outcomes consist of the National Institutes of Health Stroke Scale and the mortality. The Barthel Index(BI will also be evaluated. The sample size is 100 patients. Discussion The ECMOH trial is a randomized controlled trial designed to evaluate if endoscopic surgery is better than conservative treatment for patients with moderate-volume hematomas in the basal ganglia. Trial registration Chinese Clinical Trial Registry: ChiCTR-TRC-11001614 (http://www.chictr.org/en/proj/show.aspx?proj=1618

The Effects of Design Strength, Fly Ash Content and Curing Method on Compressive Strength of High Volume Fly Ash Concrete: A Design of Experimental

OpenAIRE

Solikin Mochamad; Setiawan Budi

2017-01-01

High volume fly ash concrete becomes one of alternatives to produce green concrete as it uses waste material and significantly reduces the utilization of Portland cement in concrete production. Although using less cement, its compressive strength is comparable to ordinary Portland cement (hereafter OPC) and the its durability increases significantly. This paper reports investigation on the effect of design strength, fly ash content and curing method on compressive strength of High Volume Fly ...

Volume of a laser-induced microjet

Science.gov (United States)

Kawamoto, Sennosuke; Hayasaka, Keisuke; Noguchi, Yuto; Tagawa, Yoshiyuki

2015-11-01

Needle-free injection systems are of great importance for medical treatments. In spite of their great potential, these systems are not commonly used. One of the common problems is strong pain caused by diffusion shape of the jet. To solve this problem, the usage of a high-speed highly-focused microjet as needle-free injection system is expected. It is thus crucial to control important indicators such as ejected volume of the jet for its safe application. We conduct experiments to reveal which parameter influences mostly the ejected volume. In the experiments, we use a glass tube of an inner diameter of 500 micro-meter, which is filled with the liquid. One end is connected to a syringe and the other end is opened. Radiating the pulse laser instantaneously vapors the liquid, followed by the generation of a shockwave. We find that the maximum volume of a laser-induced bubble is approximately proportional to the ejected volume. It is also found that the occurrence of cavitation does not affect the ejected volume while it changes the jet velocity.

Dosimetric Coverage of the Prostate, Normal Tissue Sparing, and Acute Toxicity with High-Dose-Rate Brachytherapy for Large Prostate Volumes

Directory of Open Access Journals (Sweden)

George Yang

2015-06-01

Full Text Available ABSTRACTPurposeTo evaluate dosimetric coverage of the prostate, normal tissue sparing, and acute toxicity with HDR brachytherapy for large prostate volumes.Materials and MethodsOne hundred and two prostate cancer patients with prostate volumes >50 mL (range: 5-29 mL were treated with high-dose-rate (HDR brachytherapy ± intensity modulated radiation therapy (IMRT to 4,500 cGy in 25 daily fractions between 2009 and 2013. HDR brachytherapy monotherapy doses consisted of two 1,350-1,400 cGy fractions separated by 2-3 weeks, and HDR brachytherapy boost doses consisted of two 950-1,150 cGy fractions separated by 4 weeks. Twelve of 32 (38% unfavorable intermediate risk, high risk, and very high risk patients received androgen deprivation therapy. Acute toxicity was graded according to the Common Terminology Criteria for Adverse Events (CTCAE version 4.ResultsMedian follow-up was 14 months. Dosimetric goals were achieved in over 90% of cases. Three of 102 (3% patients developed Grade 2 acute proctitis. No variables were significantly associated with Grade 2 acute proctitis. Seventeen of 102 (17% patients developed Grade 2 acute urinary retention. American Urological Association (AUA symptom score was the only variable significantly associated with Grade 2 acute urinary retention (p=0.04. There was no ≥ Grade 3 acute toxicity.ConclusionsDosimetric coverage of the prostate and normal tissue sparing were adequate in patients with prostate volumes >50 mL. Higher pre-treatment AUA symptom scores increased the relative risk of Grade 2 acute urinary retention. However, the overall incidence of acute toxicity was acceptable in patients with large prostate volumes.

Dosimetric coverage of the prostate, normal tissue sparing, and acute toxicity with high-dose-rate brachytherapy for large prostate volumes

Energy Technology Data Exchange (ETDEWEB)

Yang, George; Strom, Tobin J.; Shrinath, Kushagra; Mellon, Eric A.; Fernandez, Daniel C.; Biagioli, Matthew C. [Department of Radiation Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL (United States); Wilder, Richard B., E-mail: mcbiagioli@yahoo.com [Cancer Treatment Centers of America, Newnan, GA (United States)

2015-05-15

Purpose: to evaluate dosimetric coverage of the prostate, normal tissue sparing, and acute toxicity with HDR brachytherapy for large prostate volumes. Materials and methods: one hundred and two prostate cancer patients with prostate volumes >50 mL (range: 5-29 mL) were treated with high-dose-rate (HDR) brachytherapy ± intensity modulated radiation therapy (IMRT) to 4,500 cGy in 25 daily fractions between 2009 and 2013. HDR brachytherapy monotherapy doses consisted of two 1,350-1,400 cGy fractions separated by 2-3 weeks, and HDR brachytherapy boost doses consisted of two 950-1,150 cGy fractions separated by 4 weeks. Twelve of 32 (38%) unfavorable intermediate risk, high risk, and very high risk patients received androgen deprivation therapy. Acute toxicity was graded according to the Common Terminology Criteria for Adverse Events (CTCAE) version 4. Results: median follow-up was 14 months. Dosimetric goals were achieved in over 90% of cases. Three of 102 (3%) patients developed Grade 2 acute proctitis. No variables were significantly associated with Grade 2 acute proctitis. Seventeen of 102 (17%) patients developed Grade 2 acute urinary retention. American Urological Association (AUA) symptom score was the only variable significantly associated with Grade 2 acute urinary retention (p-0.04). There was no ≥ Grade 3 acute toxicity. Conclusions: dosimetric coverage of the prostate and normal tissue sparing were adequate in patients with prostate volumes >50 mL. Higher pre-treatment AUA symptom scores increased the relative risk of Grade 2 acute urinary retention. However, the overall incidence of acute toxicity was acceptable in patients with large prostate volumes. (author)

Deprivation and non-institutional political participation

DEFF Research Database (Denmark)

Ejrnæs, Anders

2017-01-01

This article examines how the relationship between perceived economic deprivation (PED) and non-institutional forms of political activity interacted with institutional trust during the economic crisis in 24 European countries. Using multi-level regression analysis, two broad questions are addressed......: (1) does PED have an impact on the level of non-institutional political participation among European citizens? And (2) does the level of institutional trust within countries have an impact on the relationship between PED and political activity among European citizens? The empirical analyses are based...... the opposite correlation on an individual level within the countries. Second, the analysis provides evidence that the institutional context shapes the connection between PED and political participation on the individual level. In countries with a high level of institutional trust, economically deprived...

Approaches to Identification of Institutions in Institutional Economics

Directory of Open Access Journals (Sweden)

Igor M. Shiriaev

2017-03-01

Full Text Available The paper deals with the methodology for identification of institutions from institutional economics perspective. The differences between the perspectives provided by old and new institutional economics are highlighted. These differences are interpreted in the context of compared pragmatist and postpositivist methodologies. This paper applies to the post-positivist approach to the identification of institutions. One example of institution is provided by power-property institution. Identification of this institution in the historical and economic research is based on several theoretical generalizations and supported by array of historical facts. Another example is provided by identification of institution and institutional change in higher education based on discourse analysis and interviews with the main actors. In this paper, the regulatory institutions of higher education are analyzed as well. The concept of power-property institution is extended to the higher education by proposing hypotheses on the functioning of state governing-regulating institution in this sphere. This institution prescribes the actors to behave in accordance with the objectives of public policy, which can only be implemented in the form of bureaucratization of higher education. The paper describes the behavioral regularity generated by an identified institution. Functioning of the governing-regulating institution in higher education is illustrated by examples of behavioral regularities emerging from activities in accordance with this institution. The paper also shows the possibility of falsification of proposed hypothesis.

The competitive advantage of sanctioning institutions.

Science.gov (United States)

Gürerk, Ozgür; Irlenbusch, Bernd; Rockenbach, Bettina

2006-04-07

Understanding the fundamental patterns and determinants of human cooperation and the maintenance of social order in human societies is a challenge across disciplines. The existing empirical evidence for the higher levels of cooperation when altruistic punishment is present versus when it is absent systematically ignores the institutional competition inherent in human societies. Whether punishment would be deliberately adopted and would similarly enhance cooperation when directly competing with nonpunishment institutions is highly controversial in light of recent findings on the detrimental effects of punishment. We show experimentally that a sanctioning institution is the undisputed winner in a competition with a sanction-free institution. Despite initial aversion, the entire population migrates successively to the sanctioning institution and strongly cooperates, whereas the sanction-free society becomes fully depopulated. The findings demonstrate the competitive advantage of sanctioning institutions and exemplify the emergence and manifestation of social order driven by institutional selection.

Effects of 12 weeks high-intensity & reduced-volume training in elite athletes

DEFF Research Database (Denmark)

Kilen, Anders; Larsson, Tanja Hultengren; Jørgensen, Majke

2014-01-01

It was investigated if high-intensity interval training (HIT) at the expense of total training volume improves performance, maximal oxygen uptake and swimming economy. 41 elite swimmers were randomly allocated to a control (CON) or HIT group. For 12 weeks both groups trained ∼12 h per week. HIT c...... (3.8±0.7 vs. 3.8±0.7 l O2×min-1; n = 11) group. Oxygen uptake determined at fixed submaximal speed was not significantly affected in either group by the intervention. Body fat % tended to increase (P = 0.09) in the HIT group (15.4±1.6% vs. 16.3±1.6%; P = 0.09; n = 16) and increased (P...

High Patient Satisfaction of a Hyaluronic Acid Filler Producing Enduring Full-Facial Volume Restoration: An 18-Month Open Multicenter Study.

Science.gov (United States)

Talarico, Sergio; Meski, Ana P; Buratini, Laura; Manela-Azulay, Mônica; Simpson, Helen; Sidou, Farzaneh; Kerrouche, Nabil

2015-12-01

Volume restoration is an essential part of facial rejuvenation. To assess long-term full-facial volume restoration using HAEL Volume Lidocaine hyaluronic acid filler. An 18-month open study in 60 subjects with at least Grade 2 on the 4-point volume loss scale (VLS) for full face and at least 2 indications affected among chin, temporal areas, jawline, cheeks, cheekbones, and nasolabial folds (NLF). Performance was assessed by VLS, Lemperle rating scale (LRS), investigator Global Aesthetic Improvement Scale (GAIS), and 3-dimensional (3D) imaging. Most subjects (71.6%) had 3 or 4 indications injected, most commonly cheekbones (96.7%) and NLF (93.3%). At 18 months, at least a 1-grade improvement in VLS was observed for full face (68.3% of subjects), chin (77.8%), temporal areas (73.7%), cheeks (66.6%), cheekbones (58.6%), jawline (43.1%), and NLF (71.4%; LRS). For all indications, more than 60% of the volume gained at 3 weeks was sustained at 18 months based on 3D digital imaging. At 18 months, 95.0% of subjects had improved full-face GAIS and all subjects were satisfied with their aesthetic outcome. One subject (1.6%) had treatment-related adverse events. Full-facial volume restoration was well sustained over 18 months with high patient satisfaction and good tolerability.

Current practice of incineration of low-level institutional radioactive waste

International Nuclear Information System (INIS)