WorldWideScience

Sample records for high density fiberoptic

  1. Fiber optic chemical sensors: The evolution of high- density fiber-optic DNA microarrays

    Science.gov (United States)

    Ferguson, Jane A.

    2001-06-01

    Sensors were developed for multianalyte monitoring, fermentation monitoring, lactate analysis, remote oxygen detection for use in bioremediation monitoring and in a fuel spill clean-up project, heavy metal analysis, and high density DNA microarrays. The major focus of this thesis involved creating and improving high-density DNA gene arrays. Fiber optic sensors are created using fluorescent indicators, polymeric supports, and optical fiber substrates. The fluorescent indicator is entrapped in a polymer layer and attached to the tip of the optical fiber. The tip of the fiber bearing the sensing layer (the distal end) is placed in the sample of interest while the other end of the fiber (the proximal end) is connected to an analysis system. Any length of fiber can be used without compromising the integrity or sensitivity of the system. A fiber optic oxygen sensor was designed incorporating an oxygen sensitive fluorescent dye and a gas permeable polymer attached to an optical fiber. The construction simplicity and ruggedness of the sensor enabled its deployment for in situ chemical oxidation and bioremediation studies. Optical fibers were also used as the substrate to detect biomolecules in solution. To monitor bioprocesses, the production of the analyte of interest must be coupled with a species that is optically measurable. For example, oxygen is consumed in many metabolic functions. The fiber optic oxygen sensor is equipped with an additional sensing layer. Upon contact with a specific biochemical in the sample, a reaction occurs in the additional sensing layer that either consumes or produces oxygen. This dual layer system was used to monitor the presence of lactate, an important metabolite for clinical and bioprocess analysis. In many biological and environmental systems, the generation of one species occurs coincidentally with the generation or consumption of another species. A multianalyte sensor was prepared that can monitor the simultaneous activity of pH, CO2

  2. High Temperature Fiberoptic Thermal Imaging System Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The proposed Phase 1 program will fabricate and demonstrate a small diameter single fiber endoscope that can perform high temperature thermal imaging in a jet engine...

  3. Design of high-capacity fiber-optic transport systems

    Science.gov (United States)

    Liao, Zhi Ming

    2001-08-01

    We study the design of fiber-optic transport systems and the behavior of fiber amplifiers/lasers with the aim of achieving higher capacities with larger amplifier spacing. Solitons are natural candidates for transmitting short pulses for high-capacity fiber-optic networks because of its innate ability to use two of fiber's main defects, fiber dispersion and fiber nonlinearity to balance each other. In order for solitons to retain its dynamic nature, amplifiers must be placed periodically to restore powers to compensate for fiber loss. Variational analysis is used to study the long-term stability of a periodical- amplifier system. A new regime of operation is identified which allows the use of a much longer amplifier spacing. If optical fibers are the blood vessels of an optical communication system, then the optical amplifier based on erbium-doped fiber is the heart. Optical communication systems can avoid the use of costly electrical regenerators to maintain system performance by being able to optically amplify the weakened signals. The length of amplifier spacing is largely determined by the gain excursion experienced by the solitons. We propose, model, and demonstrate a distributed erbium-doped fiber amplifier which can drastically reduce the amount of gain excursion experienced by the solitons, therefore allowing a much longer amplifier spacing and superior stability. Dispersion management techniques have become extremely valuable tools in the design of fiber-optic communication systems. We have studied in depth the advantage of different arnplification schemes (lumped and distributed) for various dispersion compensation techniques. We measure the system performance through the Q factor to evaluate the added advantage of effective noise figure and smaller gain excursion. An erbium-doped fiber laser has been constructed and characterized in an effort to develop a test bed to study transmission systems. The presence of mode-partition noise in an erbium

  4. Application and the key technology on high power fiber-optic laser in laser weapon

    Science.gov (United States)

    Qu, Zhou; Li, Qiushi; Meng, Haihong; Sui, Xin; Zhang, Hongtao; Zhai, Xuhua

    2014-12-01

    The soft-killing laser weapon plays an important role in photoelectric defense technology. It can be used for photoelectric detection, search, blinding of photoelectric sensor and other devices on fire control and guidance devices, therefore it draws more and more attentions by many scholars. High power fiber-optic laser has many virtues such as small volume, simple structure, nimble handling, high efficiency, qualified light beam, easy thermal management, leading to blinding. Consequently, it may be used as the key device of soft-killing laser weapon. The present study introduced the development of high power fiber-optic laser and its main features. Meanwhile the key technology of large mode area (LMA) optical fiber design, the beam combination technology, double-clad fiber technology and pumping optical coupling technology was stated. The present study is aimed to design high doping LMA fiber, ensure single mode output by increasing core diameter and decrease NA. By means of reducing the spontaneous emission particle absorbed by fiber core and Increasing the power density in the optical fiber, the threshold power of nonlinear effect can increase, and the power of single fiber will be improved. Meantime, high power will be obtained by the beam combination technology. Application prospect of high power fiber laser in photoelectric defense technology was also set forth. Lastly, the present study explored the advantages of high power fiber laser in photoelectric defense technology.

  5. A design of High-precision High-Voltage Fiber-Optic Analog Signal Isolation Converter

    Institute of Scientific and Technical Information of China (English)

    李建伟; 许留伟; 刘小宁; 杨雷

    2002-01-01

    This paper introduces a design of high-prectison high-voltage fiber-optic analog sig-nal isoaltion converter based on the technology of Voltage-to-Fequency (V/F)and Frequency -to Voltage(F/V) conversion It describes the principle ,system configuration and hardware design

  6. Design of a fiber-optic transmitter for microwave analog transmission with high phase stability

    Science.gov (United States)

    Logan, R. T., Jr.; Lutes, G. F.; Primas, L. E.; Maleki, L.

    1990-01-01

    The principal considerations in the design of fiber-optic transmitters for highly phase-stable radio frequency and microwave analog transmission are discussed. Criteria for a fiber-optic transmitter design with improved amplitude and phase-noise performance are developed through consideration of factors affecting the phase noise, including low-frequency laser-bias supply noise, the magnitude and proximity of external reflections into the laser, and temperature excursions of the laser-transmitter package.

  7. Proven high-reliability assembly methods applied to avionics fiber-optics high-speed transceivers

    Science.gov (United States)

    Lauzon, Jocelyn; Leduc, Lorrain; Bessette, Daniel; Bélanger, Nicolas; Larose, Robert; Dion, Bruno

    2012-06-01

    Harsh environment avionics applications require operating temperature ranges that can extend to, and exceed -50 to 115°C. For obvious maintenance, management and cost arguments, product lifetimes as long as 20 years are also sought. This leads to mandatory long-term hermeticity that cannot be obtained with epoxy or silicone sealing; but only with glass seal or metal solder or brazing. A hermetic design can indirectly result in the required RF shielding of the component. For fiber-optics products, these specifications need to be compatible with the smallest possible size, weight and power consumption. The products also need to offer the best possible high-speed performances added to the known EMI immunity in the transmission lines. Fiber-optics transceivers with data rates per fiber channel up to 10Gbps are now starting to be offered on the market for avionics applications. Some of them are being developed by companies involved in the "normal environment" telecommunications market that are trying to ruggedize their products packaging in order to diversify their customer base. Another approach, for which we will present detailed results, is to go back to the drawing boards and design a new product that is adapted to proven MIL-PRF-38534 high-reliability packaging assembly methods. These methods will lead to the introduction of additional requirements at the components level; such as long-term high-temperature resistance for the fiber-optic cables. We will compare both approaches and demonstrate the latter, associated with the redesign, is the preferable one. The performance of the fiber-optic transceiver we have developed, in terms of qualification tests such as temperature cycling, constant acceleration, hermeticity, residual gaz analysis, operation under random vibration and mechanical shocks and accelerated lifetime tests will be presented. The tests are still under way, but so far, we have observed no performance degradation of such a product after more than

  8. Constellation Shaping for Fiber-optic Channels with QAM and High Spectral Efficiency

    DEFF Research Database (Denmark)

    Yankov, Metodi Plamenov; Zibar, Darko; Larsen, Knud J.;

    2014-01-01

    In this letter the fiber-optic communication channel with Quadrature Amplitude Modulation (QAM) input constella- tion is treated. Using probabilistic shaping, we show that high order QAM constellations can achieve and slightly exceed the lower bound on the channel capacity, set by ring constellat......In this letter the fiber-optic communication channel with Quadrature Amplitude Modulation (QAM) input constella- tion is treated. Using probabilistic shaping, we show that high order QAM constellations can achieve and slightly exceed the lower bound on the channel capacity, set by ring...... constellations in [1]. We then propose a mapping function for turbo coded bit interleaved coded modulation based on optimization of the mu- tual information between the channel input and output. Using this mapping, spectral efficiency as high as 6.5 bits/s/Hz/polarization is achieved on a simulated single...

  9. Constellation Shaping for Fiber-optic Channels with QAM and High Spectral Efficiency

    DEFF Research Database (Denmark)

    Yankov, Metodi Plamenov; Zibar, Darko; Larsen, Knud J.

    2014-01-01

    channel long-haul fiber-optical link excluding the pilot overhead, used for synchronization, and taking into account frequency and phase mismatch impairments, as well as laser phase noise and analog-to-digital conversion quantization impairments. The simulations suggest that major improvements can......In this letter the fiber-optic communication channel with Quadrature Amplitude Modulation (QAM) input constella- tion is treated. Using probabilistic shaping, we show that high order QAM constellations can achieve and slightly exceed the lower bound on the channel capacity, set by ring...... constellations in [1]. We then propose a mapping function for turbo coded bit interleaved coded modulation based on optimization of the mu- tual information between the channel input and output. Using this mapping, spectral efficiency as high as 6.5 bits/s/Hz/polarization is achieved on a simulated single...

  10. Rad-Tolerant, Thermally Stable, High-Speed Fiber-Optic Network for Harsh Environments

    Science.gov (United States)

    Leftwich, Matt; Hull, Tony; Leary, Michael; Leftwich, Marcus

    2013-01-01

    Future NASA destinations will be challenging to get to, have extreme environmental conditions, and may present difficulty in retrieving a spacecraft or its data. Space Photonics is developing a radiation-tolerant (rad-tolerant), high-speed, multi-channel fiber-optic transceiver, associated reconfigurable intelligent node communications architecture, and supporting hardware for intravehicular and ground-based optical networking applications. Data rates approaching 3.2 Gbps per channel will be achieved.

  11. A Miniature Fiber-Optic Sensor for High-Resolution and High-Speed Temperature Sensing in Ocean Environment

    Science.gov (United States)

    2015-11-05

    fiber-optic sensor for high-resolution and high-speed temperature sensing in ocean environment Guigen Liu1, Ming Han1,* Weilin Hou2, Silvia Matt2... sensor performance. In this paper, we present an optical fiber sensor for the high-resolution and high-speed temperature profiling. The developed sensor ...silicon, such as large thermal diffusivity, notable thermo-optic effects and thermal expansion coefficients of silicon, the proposed sensor exhibits

  12. Miniaturized Fiber-Optic Fabry-Perot Interferometer for Highly Sensitive Refractive Index Measurement

    Institute of Scientific and Technical Information of China (English)

    Ming Deng; Tao Zhu; Yun-Jiang Rao; Hong Li

    2008-01-01

    This paper presents a novel miniaturized fiber-optic Fabry-Peort interferometer (FPI) for highly sensitive refractive index measurement. This device was tested for the refractive indices of various liquids including acetone and ethanol at room temperature. The sensitivity for measurement of refractive index change of ethanol is 1138 nm/RIU at the wavelength of 1550 nm. In addition, the sensor fabrication is simple including only cleaving, splicing, and etching. The signal is stable with high visibility. Therefore, it provides a valuable tool in biological and chemical applications.

  13. High-temperature fiber-optic Fabry-Perot interferometric sensors

    Energy Technology Data Exchange (ETDEWEB)

    Ding, Wenhui; Jiang, Yi; Gao, Ran, E-mail: bitjy@bit.edu.cn [School of Optoelectronics, Beijing Institute of Technology, Beijing 100081 (China); Liu, Yuewu [Key Laboratory for Mechanics in Fluid Solid Coupling Systems, Institute of Mechanics, Chinese Academy of Science, Beijing 100190 (China)

    2015-05-15

    A photonic crystal fiber (PCF) based high-temperature fiber-optic sensor is proposed and experimentally demonstrated. The sensor head is a Fabry-Perot cavity manufactured with a short section of endless single-mode photonic crystal fiber (ESM PCF). The interferometric spectrum of the Fabry-Perot interferometer is collected by a charge coupled device linear array based micro spectrometer. A high-resolution demodulation algorithm is used to interrogate the peak wavelengths. Experimental results show that the temperature range of 1200 °C and the temperature resolution of 1 °C are achieved.

  14. High-temperature fiber-optic Fabry-Perot interferometric sensors.

    Science.gov (United States)

    Ding, Wenhui; Jiang, Yi; Gao, Ran; Liu, Yuewu

    2015-05-01

    A photonic crystal fiber (PCF) based high-temperature fiber-optic sensor is proposed and experimentally demonstrated. The sensor head is a Fabry-Perot cavity manufactured with a short section of endless single-mode photonic crystal fiber (ESM PCF). The interferometric spectrum of the Fabry-Perot interferometer is collected by a charge coupled device linear array based micro spectrometer. A high-resolution demodulation algorithm is used to interrogate the peak wavelengths. Experimental results show that the temperature range of 1200 °C and the temperature resolution of 1 °C are achieved.

  15. Measurements of High Energy X-Ray Dose Distributions Using Multi-Dimensional Fiber-Optic Radiation Detectors

    Science.gov (United States)

    Jang, Kyoung Won; Cho, Dong Hyun; Shin, Sang Hun; Lee, Bongsoo; Chung, Soon-Cheol; Tack, Gye-Rae; Yi, Jeong Han; Kim, Sin; Cho, Hyosung

    In this study, we have fabricated multi-dimensional fiber-optic radiation detectors with organic scintillators, plastic optical fibers and photo-detectors such as photodiode array and a charge-coupled device. To measure the X-ray dose distributions of the clinical linear accelerator in the tissue-equivalent medium, we have fabricated polymethylmethacrylate phantoms which have one-dimensional and two-dimensional fiber-optic detector arrays inside. The one-dimensional and two-dimensional detector arrays can be used to measure percent depth doses and surface dose distributions of high energy X-ray in the phantom respectively.

  16. High Density Matter

    Directory of Open Access Journals (Sweden)

    Stone J.R.

    2013-12-01

    Full Text Available The microscopic composition and properties of matter at super-saturation densities have been the subject of intense investigation for decades. The scarcity of experimental and observational data has led to the necessary reliance on theoretical models. There remains great uncertainty in these models which, of necessity, have to go beyond the over-simple assumption that high density matter consists only of nucleons and leptons. Heavy strange baryons, mesons and quark matter in different forms and phases have to be included to fulfil basic requirements of fundamental laws of physics. In this contribution latest developments in construction of the Equation of State (EoS of high-density matter at zero and finite temperature assuming different composition of matter will be discussed. Critical comparison of model EoS with available experimental data from heavy ion collisions and observations on neutron stars, including gravitational mass, radii and cooling patterns and data on X-ray burst sources and low mass X-ray binaries are made. Fundamental differences between the EoS of low-density, high temperature matter, such as is created in heavy ion collisions and of high-density, low temperature compact objects is discussed.

  17. High-Frequency Flush Mounted Miniature LOX Fiber-Optic Pressure Sensor II Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Luna Innovations has teamed with the University of Alabama, Huntsville, to develop a miniature flush-mounted fiber-optic pressure sensor that will allow accurate,...

  18. High-Frequency Flush Mounted Miniature LOX Fiber-Optic Pressure Sensor Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Luna Innovations is teaming with the University of Alabama, Huntsville, to develop a miniature flush-mounted fiber-optic pressure sensor that will allow accurate,...

  19. Diagnostics of two-phase flows with high concentration of a solid dispersed phase using fiber-optic sensors

    Science.gov (United States)

    Evseev, A. R.

    2016-10-01

    This paper is focused on the physical modeling of two-phase flows with high concentration of the dispersed phase. The fiber-optical sensors and their calibration procedure were developed for bubble concentration measurements in the fluidized bed apparatus (FB). Distributions of bubble concentration in the 2D and 3D FB apparatuses, which determine the quality of fluidization and local density of filling material, were obtained. The techniques of particle velocity and concentration measurements in the circulating fluidized bed (CFB) was developed using three-fiber sensor (the differential scheme of LDA) operated in backscattering regime. Sensor operation was analyzed and the main systematic measurement errors were determined; the original construction of the sensor was designed. The data on the velocity and concentration profiles of dispersed phase in a large-scale CFB apparatus were obtained for fluidization of particles by air. It was found that with increasing circulation velocity in the CFB apparatus, the particle concentration increases in the near-wall region much higher than in the flow core. The method of particle velocity measurements in a liquid was developed using the laser Doppler fiber anemometer (LDFA-1), operating in the backscattering regime. The signal to noise ratio was obtained for particles of different size and material in test measurements. The rates of consolidated precipitation of cryolite particles in a sedimentation apparatus with the inclined walls were measured.

  20. An arc tangent function demodulation method of fiber-optic Fabry-Perot high-temperature pressure sensor

    Science.gov (United States)

    Ren, Qianyu; Li, Junhong; Hong, Yingping; Jia, Pinggang; Xiong, Jijun

    2017-09-01

    A new demodulation algorithm of the fiber-optic Fabry-Perot cavity length based on the phase generated carrier (PGC) is proposed in this paper, which can be applied in the high-temperature pressure sensor. This new algorithm based on arc tangent function outputs two orthogonal signals by utilizing an optical system, which is designed based on the field-programmable gate array (FPGA) to overcome the range limit of the original PGC arc tangent function demodulation algorithm. The simulation and analysis are also carried on. According to the analysis of demodulation speed and precision, the simulation of different numbers of sampling points, and measurement results of the pressure sensor, the arc tangent function demodulation method has good demodulation results: 1 MHz processing speed of single data and less than 1% error showing practical feasibility in the fiber-optic Fabry-Perot cavity length demodulation of the Fabry-Perot high-temperature pressure sensor.

  1. Highly sensitive fiber-optic accelerometer by grating inscription in specific core dip fiber.

    Science.gov (United States)

    Rong, Qiangzhou; Guo, Tuan; Bao, Weijia; Shao, Zhihua; Peng, Gang-Ding; Qiao, Xueguang

    2017-09-19

    A highly sensitive fiber-optic accelerometer based on detecting the power output of resonances from the core dip is demonstrated. The sensing probe comprises a compact structure, hereby a short section of specific core (with a significant core dip) fiber stub containing a straight fiber Bragg grating is spliced to another single-mode fiber via a core self-alignment process. The femtosecond laser side-illumination technique was utilized to ensure that the grating inscription region is precisely positioned and compact in size. Two well-defined core resonances were achieved in reflection: one originates from the core dip and the other originates from fiber core. The key point is that only one of these two reflective resonances exhibits a high sensitivity to fiber bend (and vibration), whereas the other is immune to it. For low frequency (core mode reflection. Moreover, the sensor simultaneously provides an inherent power reference to eliminate unwanted power fluctuations from the light source and transmission lines, thus providing a means of evaluating weak seismic wave at low frequency.

  2. MEMS fiber-optic Fabry-Perot pressure sensor for high temperature application

    Science.gov (United States)

    Fang, G. C.; Jia, P. G.; Cao, Q.; Xiong, J. J.

    2016-10-01

    We design and demonstrate a fiber-optic Fabry-Perot pressure sensor (FOFPPS) for high-temperature sensing by employing micro-electro-mechanical system (MEMS) technology. The FOFPPS is fabricated by anodically bonding the silicon wafer and the Pyrex glass together and fixing the facet of the optical fiber in parallel with the silicon surface by glass frit and organic adhesive. The silicon wafer can be reduced through dry etching technology to construct the sensitive diaphragm. The length of the cavity changes with the deformation of the diaphragm due to the loaded pressure, which leads to a wavelength shift of the interference spectrum. The pressure can be gauged by measuring the wavelength shift. The pressure experimental results show that the sensor has linear pressure sensitivities ranging from 0 kPa to 600 kPa at temperature range between 20°C to 300°C. The pressure sensitivity at 300°C is approximately 27.63 pm/kPa. The pressure sensitivities gradually decrease with increasing the temperature. The sensor also has a linear thermal drift when temperature changes from 20°C - 300°C.

  3. High-sensitivity four-layer polymer fiber-optic evanescent wave sensor.

    Science.gov (United States)

    Xin, Xin; Zhong, Nianbing; Liao, Qiang; Cen, Yanyan; Wu, Ruohua; Wang, Zhengkun

    2017-05-15

    We present a novel four-layer structure consisting of bottom, second, third, and surface layers in the sensing region, for a D-shaped step-index fiber-optic evanescent wave (FOEW) sensor. To reduce the background noise, the surface of the longitudinal section in the D-shaped region is coated with a light-absorbing film. We check the morphologies of the second and surface layers, examine the refractive indices (RIs) of the third and surface layers, and analyze the composition of the surface layer. We also investigate the effects of the thicknesses and RIs of the third and surface layers and the LA film on the light transmission and sensitivity of the FOEW sensors. The results highlight the very good sensitivity of the proposed FOEW sensor with a four-layer structure, which reached -0.077 (μg/l)(-1) in the detection of the target antibody; the sensitivity of the novel FOEW sensor was 7.60 and 1.52 times better than that of a conventional sensor with a core-cladding structure and an FOEW sensor with a three-layer structure doped with GeO2. The applications of this high-sensitivity FOEW sensor can be extended to biodefense, disease diagnosis, and biomedical and biochemical analysis.

  4. Flexible Fiber-Optic High-Speed Imaging of Vocal Fold Vibration: A Preliminary Report.

    Science.gov (United States)

    Woo, Peak; Baxter, Peter

    2017-03-01

    High-speed video (HSV) imaging of vocal fold vibration has been possible only through the rigid endoscope. This study reports that a fiberscope-based high-speed imaging system may allow HSV imaging of naturalistic voicing. Twenty-two subjects were recorded using a commercially available black and white high-speed camera (Photron Motion Tools, 256 × 120 pixel, 2000 frames per second, 8 second acquisition time). The camera gain is set to +6 db. The camera is coupled to a standard fiber-optic laryngoscope (Olympus ENF P-4) with a 300-W Xenon light. Image acquisition was done by asking the subject to perform repeated phonation at modal phonation. Video images were processed using commercial video editing and video noise reduction software (After effects, Magix, and Neat Video 4.1). After video processing, the video images were analyzed using digital kymography (DKG). The HSV black and white video acquired by the camera is gray and lacks contrast. By adjustment of image contrast, brightness, and gamma and using noise reduction software, the flexible laryngoscopy image can be converted to video image files suitable for DKG and waveform analysis. The increased noise still makes edge tracking for objective analysis difficult, but subjective analysis of DKG plot is possible. This is the first report of HSV acquisition in an unsedated patient using a fiberscope. Image enhancement and noise reduction can enhance the HSV to allow extraction of the digital kymogram. Further image enhancement may allow for objective analysis of the vibratory waveform. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  5. Monolithic, High-Speed Fiber-Optic Switching Array for Lidar

    Science.gov (United States)

    Suckow, Will; Roberts, Tony; Switzer, Gregg; Terwilliger, Chelle

    2011-01-01

    Current fiber switch technologies use mechanical means to redirect light beams, resulting in slow switch time, as well as poor reliability due to moving parts wearing out quickly at high speeds. A non-mechanical ability to switch laser output into one of multiple fibers within a fiber array can provide significant power, weight, and costs savings to an all-fiber system. This invention uses an array of crystals that act as miniature prisms to redirect light as an electric voltage changes the prism s properties. At the heart of the electro-optic fiber-optic switch is an electro- optic crystal patterned with tiny prisms that can deflect the beam from the input fiber into any one of the receiving fibers arranged in a linear array when a voltage is applied across the crystal. Prism boundaries are defined by a net dipole moment in the crystal lattice that has been poled opposite to the surrounding lattice fabricated using patterned, removable microelectrodes. When a voltage is applied across the crystal, the resulting electric field changes the index of refraction within the prism boundaries relative to the surrounding substrate, causing light to deflect slightly according to Snell s Law. There are several materials that can host the necessary monolithic poled pattern (including, but not limited to, SLT, KTP, LiNbO3, and Mg:LiNbO3). Be cause this is a solid-state system without moving parts, it is very fast, and does not wear down easily. This invention is applicable to all fiber networks, as well as industries that use such networks. The unit comes in a compact package, can handle both low and high voltages, and has a high reliability (100,000 hours without maintenance).

  6. Fiber-Optical Parametric Amplification of Sub-Picosecond Pulses for High-Speed Optical Communications

    DEFF Research Database (Denmark)

    Lali-Dastjerdi, Zohreh; Cristofori, Valentina; Rottwitt, Karsten

    2015-01-01

    This article reviews recent results of amplification of short optical pulses using fiber-optical parametric amplifiers. This includes chirped-pulse amplification of 400 fs pulses, error-free amplification of a 640-Gbit/s optical time-division multiplexed signal with less than a 1-dB power penalty...

  7. High Density QCD

    CERN Document Server

    Ducati, M B G

    2001-01-01

    The dynamics of high partonic density QCD is presented considering, in the double logarithm approximation, the parton recombination mechanism built in the AGL formalism, developed including unitarity corrections for the nucleon as well for nucleus. It is shown that these corrections are under theoretical control. The resulting non linear evolution equation is solved in the asymptotic regime, and a comprehensive phenomenology concerning Deep Inelastic Scattering like $F_2$, $F_L$, $F_2^c$. $\\partial F_2/ \\partial \\ln Q^2$, $\\partial F^A_2/ \\partial \\ln Q^2$, etc, is presented. The connection of our formalism with the DGLAP and BFKL dynamics, and with other perturbative (K) and non-perturbative (MV-JKLW) approaches is analised in detail. The phenomena of saturation due to shadowing corrections and the relevance of this effect in ion physics and heavy quark production is emphasized. The implications to e-RHIC, HERA-A, and LHC physics and some open questions are mentioned.

  8. A High Sensitivity and Wide Dynamic Range Fiber-Optic Sensor for Low-Concentration VOC Gas Detection

    Directory of Open Access Journals (Sweden)

    Md. Rajibur Rahaman Khan

    2014-12-01

    Full Text Available In this paper, we propose a volatile organic compound (VOC gas sensing system with high sensitivity and a wide dynamic range that is based on the principle of the heterodyne frequency modulation method. According to this method, the time period of the sensing signal shift when Nile Red containing a VOC-sensitive membrane of a fiber-optic sensing element comes into contact with a VOC. This sensing membrane produces strong, fast and reversible signals when exposed to VOC gases. The response and recovery times of the proposed sensing system were less than 35 s, and good reproducibility and accuracy were obtained.

  9. A High Sensitivity and Wide Dynamic Range Fiber-Optic Sensor for Low-Concentration VOC Gas Detection

    Science.gov (United States)

    Khan, Md. Rajibur Rahaman; Kang, Shin-Won

    2014-01-01

    In this paper, we propose a volatile organic compound (VOC) gas sensing system with high sensitivity and a wide dynamic range that is based on the principle of the heterodyne frequency modulation method. According to this method, the time period of the sensing signal shift when Nile Red containing a VOC-sensitive membrane of a fiber-optic sensing element comes into contact with a VOC. This sensing membrane produces strong, fast and reversible signals when exposed to VOC gases. The response and recovery times of the proposed sensing system were less than 35 s, and good reproducibility and accuracy were obtained. PMID:25490592

  10. Highly Sensitive Fiber-Optic Faraday-Effect Magnetic Field Sensor Based on Yttrium Iron Garnet

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    The principle and performance of a fiber-optic Faraday-effect magnetic-field sensor based on an yttrium iron garnet (YIG) and two flux concentrations are described. A single polarization maintaining optical fiber links the sensor head to the source and detection system, in which the technique of phase shift cancellation is used to cancel the phase shift that accumulate in the optical fiber. Flux concentrators were exploited to enhance the YIG crystal magneto optic sensitivity .The sensor system exhibited a noise-equivalent field of 8 and a 3 dB bandwidth of ~10 MHz.

  11. High density photovoltaic

    Energy Technology Data Exchange (ETDEWEB)

    Haigh, R.E.; Jacobson, G.F.; Wojtczuk, S. [Spire Corp., Bedford, MA (United States)

    1997-10-14

    Photovoltaic technology can directly generate high voltages in a solid state material through the series interconnect of many photovoltaic diodes. We are investigating the feasibility of developing an electrically isolated, high-voltage power supply using miniature photovoltaic devices that convert optical energy to electrical energy.

  12. High Energy Density Capacitors Project

    Data.gov (United States)

    National Aeronautics and Space Administration — NASA?s future space science missions cannot be realized without the state of the art energy storage devices which require high energy density, high reliability, and...

  13. A high sensitive fiber-optic strain sensor with tunable temperature sensitivity for temperature-compensation measurement

    Science.gov (United States)

    Hu, Jie; Huang, Hui; Bai, Min; Zhan, Tingting; Yang, Zhibo; Yu, Yan; Qu, Bo

    2017-02-01

    A high sensitive fiber-optic strain sensor, which consists of a cantilever, a tandem rod and a fiber collimator, was proposed. The tandem rod, which transfer the applied strain to the cantilever, was used for tuning the temperature sensitivity from ‑0.15 to 0.19 dB/°C via changing the length ratio of the rods. Moreover, due to the small beam divergence of the collimator, high strain sensitivity can be realized via incident-angle sensitive detection-mechanism. A strain detection-range of 1.1 × 103 με (with a sensing length of 21.5 mm), a detection limit of 5.7 × 10‑3 με, and a maximum operating frequency of 1.18 KHz were demonstrated. This sensor is promising for compensating the thermal-expansion of various target objects.

  14. Fabrication of All-SiC Fiber-Optic Pressure Sensors for High-Temperature Applications

    Directory of Open Access Journals (Sweden)

    Yonggang Jiang

    2016-10-01

    Full Text Available Single-crystal silicon carbide (SiC-based pressure sensors can be used in harsh environments, as they exhibit stable mechanical and electrical properties at elevated temperatures. A fiber-optic pressure sensor with an all-SiC sensor head was fabricated and is herein proposed. SiC sensor diaphragms were fabricated via an ultrasonic vibration mill-grinding (UVMG method, which resulted in a small grinding force and low surface roughness. The sensor head was formed by hermetically bonding two layers of SiC using a nickel diffusion bonding method. The pressure sensor illustrated a good linearity in the range of 0.1–0.9 MPa, with a resolution of 0.27% F.S. (full scale at room temperature.

  15. Design, analysis, and initial testing of a fiber-optic shear gage for three-dimensional, high-temperature flows

    Science.gov (United States)

    Orr, Matthew W.

    This investigation concerns the design, analysis, and initial testing of a new, two-component wall shear gage for 3D, high-temperature flows. This gage is a direct-measuring, non-nulling design with a round head surrounded by a small gap. Two flexure wheels are used to allow small motions of the floating head. Fiber-optic displacement sensors measure how far the polished faces of counterweights on the wheels move in relation to a fixed housing as the primary measurement system. No viscous damping was required. The gage has both fiber-optic instrumentation and strain gages mounted on the flexures for validation of the newer fiber optics. The sensor is constructed of Haynes RTM 230RTM, a high-temperature nickel alloy. The gage housing is made of 316 stainless steel. All components of the gage in pure fiber-optic form can survive to a temperature of 1073 K. The bonding methods of the backup strain gages limit their maximum temperature to 473 K. The dynamic range of the gage is from 0--500 Pa (0--10g) and higher shears can be measured by changing the floating head size. Extensive use of finite element modeling was critical to the design and analysis of the gage. Static structural, modal, and thermal analyses were performed on the flexures using the ANSYS finite element package. Static finite element analysis predicted the response of the flexures to a given load, and static calibrations using a direct force method confirmed these results. Finite element modal analysis results were within 16.4% for the first mode and within 30% for the second mode when compared with the experimentally determined modes. Vibration characteristics of the gage were determined from experimental free vibration data after the gage was subjected to an impulse. Uncertainties in the finished geometry make this level of error acceptable. A transient thermal analysis examined the effects of a very high heat flux on the exposed head of the gage. The 100,000 W/m2 heat flux used in this analysis is

  16. Highly Sensitive Temperature Sensors Based on Fiber-Optic PWM and Capacitance Variation Using Thermochromic Sensing Membrane.

    Science.gov (United States)

    Khan, Md Rajibur Rahaman; Kang, Shin-Won

    2016-07-09

    In this paper, we propose a temperature/thermal sensor that contains a Rhodamine-B sensing membrane. We applied two different sensing methods, namely, fiber-optic pulse width modulation (PWM) and an interdigitated capacitor (IDC)-based temperature sensor to measure the temperature from 5 °C to 100 °C. To the best of our knowledge, the fiber-optic PWM-based temperature sensor is reported for the first time in this study. The proposed fiber-optic PWM temperature sensor has good sensing ability; its sensitivity is ~3.733 mV/°C. The designed temperature-sensing system offers stable sensing responses over a wide dynamic range, good reproducibility properties with a relative standard deviation (RSD) of ~0.021, and the capacity for a linear sensing response with a correlation coefficient of R² ≈ 0.992 over a wide sensing range. In our study, we also developed an IDC temperature sensor that is based on the capacitance variation principle as the IDC sensing element is heated. We compared the performance of the proposed temperature-sensing systems with different fiber-optic temperature sensors (which are based on the fiber-optic wavelength shift method, the long grating fiber-optic Sagnac loop, and probe type fiber-optics) in terms of sensitivity, dynamic range, and linearity. We observed that the proposed sensing systems have better sensing performance than the above-mentioned sensing system.

  17. High Energy Density Laboratory Astrophysics

    CERN Document Server

    Lebedev, Sergey V

    2007-01-01

    During the past decade, research teams around the world have developed astrophysics-relevant research utilizing high energy-density facilities such as intense lasers and z-pinches. Every two years, at the International conference on High Energy Density Laboratory Astrophysics, scientists interested in this emerging field discuss the progress in topics covering: - Stellar evolution, stellar envelopes, opacities, radiation transport - Planetary Interiors, high-pressure EOS, dense plasma atomic physics - Supernovae, gamma-ray bursts, exploding systems, strong shocks, turbulent mixing - Supernova remnants, shock processing, radiative shocks - Astrophysical jets, high-Mach-number flows, magnetized radiative jets, magnetic reconnection - Compact object accretion disks, x-ray photoionized plasmas - Ultrastrong fields, particle acceleration, collisionless shocks. These proceedings cover many of the invited and contributed papers presented at the 6th International Conference on High Energy Density Laboratory Astrophys...

  18. Saturation and High Density QCD

    OpenAIRE

    Mueller, A. H.

    2005-01-01

    Recent progress in understanding general properties of high energy scattering near the unitarity limit, where high density gluon components of the wavefunction are dominant, is reviewed. The similarity of the QCD problem and that of reaction-diffusion processes in statistical physics is emphasized. The energy dependence of the saturation momentum and the status of geometric scaling are discussed.

  19. In Site Analysis of a High Temperature Cure Reaction in Real Time Using Modulated Fiber-Optic FT-Raman Spectroscopy

    Science.gov (United States)

    Cooper, John; Aust, Jeffrey F.; Wise, Kent L.; Jensen, Brian J.

    1999-01-01

    The vibrational spectrum of a high temperature (330 C) polymerization reaction was successfully monitored in real time using a modulated fiber-optic FT-Raman spectrometer. A phenylethynyl terminated monomer was cured, and spectral evidence for two different reaction products was acquired. The products are a conjugated polyene chain and a cyclized trimer. This is the first report describing the use of FT-Raman spectroscopy to monitor a high temperature (greater than 250 C) reaction in real time.

  20. A novel fiber-optic temperature sensor based on high temperature-dependent optical properties of ZnO film on sapphire fiber-ending

    Energy Technology Data Exchange (ETDEWEB)

    Cai Pinggen; Zhen Dong; Xu Xiaojun; Liu Yulin [Department of Applied Physics, Zhejiang University of Technology, 18 Chaowang Road, Hangzhou 310014, Zhejiang Province (China); Chen Naibo [Department of Science, Zhijiang College of Zhejiang University of Technology, Hangzhou 310024 (China); Wei Gaorao [Department of Applied Physics, Zhejiang University of Technology, 18 Chaowang Road, Hangzhou 310014, Zhejiang Province (China); Sui Chenghua, E-mail: suich@zjut.edu.cn [Department of Applied Physics, Zhejiang University of Technology, 18 Chaowang Road, Hangzhou 310014, Zhejiang Province (China)

    2010-07-25

    We report the growth of high-quality thin films of ZnO via an electron-beam evaporation technique. Studies of the transmittance spectra have revealed a sharp optical absorption edge and a significant redshift. After annealing at 673 K, the ZnO films again demonstrated a sharp absorption edge in a manner similar to the as-deposited samples. This illustrates the excellent thermal stability of the thin films and, as such, demonstrates their potential as fiber-optic temperature sensors. Utilizing the influence of optical absorption spectra at different temperatures, a novel fiber-optic temperature sensor based on this material has been designed and tested. This technique could offer a simple, robust and cost-effective method to be used in high temperature sensing applications.

  1. Enhancing thermal reliability of fiber-optic sensors for bio-inspired applications at ultra-high temperatures

    Science.gov (United States)

    Kang, Donghoon; Kim, Heon-Young; Kim, Dae-Hyun

    2014-07-01

    The rapid growth of bio-(inspired) sensors has led to an improvement in modern healthcare and human-robot systems in recent years. Higher levels of reliability and better flexibility, essential features of these sensors, are very much required in many application fields (e.g. applications at ultra-high temperatures). Fiber-optic sensors, and fiber Bragg grating (FBG) sensors in particular, are being widely studied as suitable sensors for improved structural health monitoring (SHM) due to their many merits. To enhance the thermal reliability of FBG sensors, thermal sensitivity, generally expressed as αf + ξf and considered a constant, should be investigated more precisely. For this purpose, the governing equation of FBG sensors is modified using differential derivatives between the wavelength shift and the temperature change in this study. Through a thermal test ranging from RT to 900 °C, the thermal sensitivity of FBG sensors is successfully examined and this guarantees thermal reliability of FBG sensors at ultra-high temperatures. In detail, αf + ξf has a non-linear dependence on temperature and varies from 6.0 × 10-6 °C-1 (20 °C) to 10.6 × 10-6 °C-1 (650 °C). Also, FBGs should be carefully used for applications at ultra-high temperatures due to signal disappearance near 900 °C.

  2. High-density multicore fibers

    DEFF Research Database (Denmark)

    Takenaga, K.; Matsuo, S.; Saitoh, K.;

    2016-01-01

    High-density single-mode multicore fibers were designed and fabricated. A heterogeneous 30-core fiber realized a low crosstalk of −55 dB. A quasi-single-mode homogeneous 31-core fiber attained the highest core count as a single-mode multicore fiber....

  3. High density matter at RHIC

    Indian Academy of Sciences (India)

    Thomas S Ullrich

    2004-02-01

    QCD predicts a phase transition between hadronic matter and a quark-gluon plasma at high energy density. The relativistic heavy ion collider (RHIC) at Brookhaven National Laboratory is a new facility dedicated to the experimental study of matter under extreme conditions. Already the first round of experimental results at RHIC indicated that the conditions to create a new state of matter are indeed reached in the collisions of heavy nuclei. Studies of particle spectra and their correlations at low transverse momenta provide evidence of strong pressure gradients in the highly interacting dense medium and hint that we observe a system in thermal equilibrium. Recent runs with high statistics allow us to explore the regime of hard-scattering processes where the suppression of hadrons at large transverse momentum, and quenching of di-jets are observed thus providing further evidence for extreme high density matter created in collisions at RHIC.

  4. A Highly Sensitive Fiber-Optic Fabry-Perot Interferometer Based on Internal Reflection Mirrors for Refractive Index Measurement.

    Science.gov (United States)

    Li, Xuefeng; Shao, Yujiao; Yu, Yuan; Zhang, Yin; Wei, Shaowen

    2016-05-31

    In this study, a new type of highly sensitive fiber-optic Fabry-Perot interferometer (FFPI) is proposed with a high sensitivity on a wide refractive index (RI) measurement range based on internal reflection mirrors of micro-cavity. The sensor head consists of a single-mode fiber (SMF) with an open micro-cavity. Since light reflections of gold thin films are not affected by the RI of different measuring mediums, the sensor is designed to improve the fringe visibility of optical interference through sputtering the gold films of various thicknesses on the inner surfaces of the micro-cavity, as a semi-transparent mirror (STM) and a total-reflection mirror (TRM). Experiments have been carried out to verify the feasibility of the sensor's design. It is shown that the fabricated sensor has strong interference visibility exceeding 15 dB over a wide measurement range of RI, and the sensor sensitivity is higher than 1160 nm/RIU, and RI resolution is better than 1.0 × 10(-6) RIU.

  5. High density fluoride glass calorimeter

    Science.gov (United States)

    Xie, Q.; Scheltzbaum, J.; Akgun, U.

    2014-04-01

    The unprecedented radiation levels in current Large Hadron Collider runs, and plans to even increase the luminosity creates a need for new detector technologies to be investigated. Quartz plates to replace the plastic scintillators in current LHC calorimeters have been proposed in recent reports. Quartz based Cherenkov calorimeters can solve the radiation damage problem, however light production and transfer have proven to be challenging. This report summarizes the results from a computational study on the performance of a high-density glass calorimeter. High-density, scintillating, fluoride glass, CHG3, was used as the active material. This glass has been developed specifically for hadron collider experiments, and is known for fast response time, in addition to high light yield. Here, the details of a Geant4 model for a sampling calorimeter prototype with 20 layers, and its hadronic as well as electromagnetic performances are reported.

  6. Advanced Components For Fiber-Optical Systems

    Science.gov (United States)

    Depaula, Ramon; Stowe, David W.

    1989-01-01

    Paper reviews statuses of some advanced passive and active optical components for use with optical fibers. Emphasis on highly birefringent components controling polarization, because control of polarization critical in applications as fiber-optical gyroscopes, interferometric sensors, and coherent communications.

  7. High energy density aluminum battery

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Gilbert M.; Paranthaman, Mariappan Parans; Dai, Sheng; Dudney, Nancy J.; Manthiram, Arumugan; McIntyre, Timothy J.; Sun, Xiao-Guang; Liu, Hansan

    2016-10-11

    Compositions and methods of making are provided for a high energy density aluminum battery. The battery comprises an anode comprising aluminum metal. The battery further comprises a cathode comprising a material capable of intercalating aluminum or lithium ions during a discharge cycle and deintercalating the aluminum or lithium ions during a charge cycle. The battery further comprises an electrolyte capable of supporting reversible deposition and stripping of aluminum at the anode, and reversible intercalation and deintercalation of aluminum or lithium at the cathode.

  8. High energy density aluminum battery

    Science.gov (United States)

    Brown, Gilbert M.; Paranthaman, Mariappan Parans; Dai, Sheng; Dudney, Nancy J.; Manthiram, Arumugan; McIntyre, Timothy J.; Sun, Xiao-Guang; Liu, Hansan

    2016-10-11

    Compositions and methods of making are provided for a high energy density aluminum battery. The battery comprises an anode comprising aluminum metal. The battery further comprises a cathode comprising a material capable of intercalating aluminum or lithium ions during a discharge cycle and deintercalating the aluminum or lithium ions during a charge cycle. The battery further comprises an electrolyte capable of supporting reversible deposition and stripping of aluminum at the anode, and reversible intercalation and deintercalation of aluminum or lithium at the cathode.

  9. Simultaneous fingerprint and high-wavenumber fiber-optic Raman spectroscopy improves in vivo diagnosis of esophageal squamous cell carcinoma at endoscopy

    Science.gov (United States)

    Wang, Jianfeng; Lin, Kan; Zheng, Wei; Yu Ho, Khek; Teh, Ming; Guan Yeoh, Khay; Huang, Zhiwei

    2015-01-01

    This work aims to evaluate clinical value of a fiber-optic Raman spectroscopy technique developed for in vivo diagnosis of esophageal squamous cell carcinoma (ESCC) during clinical endoscopy. We have developed a rapid fiber-optic Raman endoscopic system capable of simultaneously acquiring both fingerprint (FP)(800–1800 cm−1) and high-wavenumber (HW)(2800–3600 cm−1) Raman spectra from esophageal tissue in vivo. A total of 1172 in vivo FP/HW Raman spectra were acquired from 48 esophageal patients undergoing endoscopic examination. The total Raman dataset was split into two parts: 80% for training; while 20% for testing. Partial least squares-discriminant analysis (PLS-DA) and leave-one patient-out, cross validation (LOPCV) were implemented on training dataset to develop diagnostic algorithms for tissue classification. PLS-DA-LOPCV shows that simultaneous FP/HW Raman spectroscopy on training dataset provides a diagnostic sensitivity of 97.0% and specificity of 97.4% for ESCC classification. Further, the diagnostic algorithm applied to the independent testing dataset based on simultaneous FP/HW Raman technique gives a predictive diagnostic sensitivity of 92.7% and specificity of 93.6% for ESCC identification, which is superior to either FP or HW Raman technique alone. This work demonstrates that the simultaneous FP/HW fiber-optic Raman spectroscopy technique improves real-time in vivo diagnosis of esophageal neoplasia at endoscopy. PMID:26243571

  10. In Situ Analysis of a High-Temperature Cure Reaction in Real Time Using Modulated Fiber-Optic FT-Raman Spectroscopy

    Science.gov (United States)

    Aust, Jeffrey F.; Cooper, John B.; Wise, Kent L.; Jensen, Brian J.

    1999-01-01

    The vibrational spectrum of a high-temperature (330 C) polymerization reaction was successfully monitored in real time with the use of a modulated fiber-optic Fourier transform (FT)-Raman spectrometer. A phenylethynyl-terminated monomer was cured, and spectral evidence for two different reaction products was acquired. The products are a conjugated polyene chain and a cyclized trimer. This is the first report describing the use of FT-Raman spectroscopy to monitor a high temperature (greater than 250 C) reaction in real time.

  11. A Fiber-Optic Sensor for Acoustic Emission Detection in a High Voltage Cable System

    Directory of Open Access Journals (Sweden)

    Tongzhi Zhang

    2016-11-01

    Full Text Available We have proposed and demonstrated a Michelson interferometer-based fiber sensor for detecting acoustic emission generated from the partial discharge (PD of the accessories of a high-voltage cable system. The developed sensor head is integrated with a compact and relatively high sensitivity cylindrical elastomer. Such a sensor has a broadband frequency response and a relatively high sensitivity in a harsh environment under a high-voltage electric field. The design and fabrication of the sensor head integrated with the cylindrical elastomer is described, and a series of experiments was conducted to evaluate the sensing performance. The experimental results demonstrate that the sensitivity of our developed sensor for acoustic detection of partial discharges is 1.7 rad / ( m ⋅ Pa . A high frequency response up to 150 kHz is achieved. Moreover, the relatively high sensitivity for the detection of PD is verified in both the laboratory environment and gas insulated switchgear. The obtained results show the great potential application of a Michelson interferometer-based fiber sensor integrated with a cylindrical elastomer for in-situ monitoring high-voltage cable accessories for safety work.

  12. A Fiber-Optic Sensor for Acoustic Emission Detection in a High Voltage Cable System.

    Science.gov (United States)

    Zhang, Tongzhi; Pang, Fufei; Liu, Huanhuan; Cheng, Jiajing; Lv, Longbao; Zhang, Xiaobei; Chen, Na; Wang, Tingyun

    2016-11-30

    We have proposed and demonstrated a Michelson interferometer-based fiber sensor for detecting acoustic emission generated from the partial discharge (PD) of the accessories of a high-voltage cable system. The developed sensor head is integrated with a compact and relatively high sensitivity cylindrical elastomer. Such a sensor has a broadband frequency response and a relatively high sensitivity in a harsh environment under a high-voltage electric field. The design and fabrication of the sensor head integrated with the cylindrical elastomer is described, and a series of experiments was conducted to evaluate the sensing performance. The experimental results demonstrate that the sensitivity of our developed sensor for acoustic detection of partial discharges is 1.7 rad / ( m ⋅ Pa ) . A high frequency response up to 150 kHz is achieved. Moreover, the relatively high sensitivity for the detection of PD is verified in both the laboratory environment and gas insulated switchgear. The obtained results show the great potential application of a Michelson interferometer-based fiber sensor integrated with a cylindrical elastomer for in-situ monitoring high-voltage cable accessories for safety work.

  13. Monolithic, High-Speed Fiber-Optic Switching Array for Lidar Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This NASA SBIR Phase II effort will develop a 1 x 10 prototype non-mechanical fiber optic switch for use with high power lasers. The proposed optical device is a...

  14. Fiber-Optic Etalon Pressure Sensor System with High Thermal and Mechanical Stabilities Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Atmospheric pressure sensing in particular is of critical importance to any attemp of Mars landing. Pressure sensing has traditionally always drawn high interest...

  15. Intelligent Monitoring System with High Temperature Distributed Fiberoptic Sensor for Power Plant Combustion Processes

    Energy Technology Data Exchange (ETDEWEB)

    Kwang Y. Lee; Stuart S. Yin; Andre Boehman

    2006-09-26

    The objective of the proposed work is to develop an intelligent distributed fiber optical sensor system for real-time monitoring of high temperature in a boiler furnace in power plants. Of particular interest is the estimation of spatial and temporal distributions of high temperatures within a boiler furnace, which will be essential in assessing and controlling the mechanisms that form and remove pollutants at the source, such as NOx. The basic approach in developing the proposed sensor system is three fold: (1) development of high temperature distributed fiber optical sensor capable of measuring temperatures greater than 2000 C degree with spatial resolution of less than 1 cm; (2) development of distributed parameter system (DPS) models to map the three-dimensional (3D) temperature distribution for the furnace; and (3) development of an intelligent monitoring system for real-time monitoring of the 3D boiler temperature distribution. Under Task 1, we have set up a dedicated high power, ultrafast laser system for fabricating in-fiber gratings in harsh environment optical fibers, successfully fabricated gratings in single crystal sapphire fibers by the high power laser system, and developed highly sensitive long period gratings (lpg) by electric arc. Under Task 2, relevant mathematical modeling studies of NOx formation in practical combustors have been completed. Studies show that in boiler systems with no swirl, the distributed temperature sensor may provide information sufficient to predict trends of NOx at the boiler exit. Under Task 3, we have investigated a mathematical approach to extrapolation of the temperature distribution within a power plant boiler facility, using a combination of a modified neural network architecture and semigroup theory. Given a set of empirical data with no analytic expression, we first developed an analytic description and then extended that model along a single axis.

  16. Intelligent Monitoring System With High Temperature Distributed Fiberoptic Sensor For Power Plant Combustion Processes

    Energy Technology Data Exchange (ETDEWEB)

    Kwang Y. Lee; Stuart S. Yin; Andre Boheman

    2005-12-26

    The objective of the proposed work is to develop an intelligent distributed fiber optical sensor system for real-time monitoring of high temperature in a boiler furnace in power plants. Of particular interest is the estimation of spatial and temporal distributions of high temperatures within a boiler furnace, which will be essential in assessing and controlling the mechanisms that form and remove pollutants at the source, such as NOx. The basic approach in developing the proposed sensor system is three fold: (1) development of high temperature distributed fiber optical sensor capable of measuring temperatures greater than 2000 C degree with spatial resolution of less than 1 cm; (2) development of distributed parameter system (DPS) models to map the three-dimensional (3D) temperature distribution for the furnace; and (3) development of an intelligent monitoring system for real-time monitoring of the 3D boiler temperature distribution. Under Task 1, we set up a dedicated high power, ultrafast laser system for fabricating in-fiber gratings in harsh environment optical fibers, successfully fabricated gratings in single crystal sapphire fibers by the high power laser system, and developed highly sensitive long period gratings (lpg) by electric arc. Under Task 2, relevant mathematical modeling studies of NOx formation in practical combustors. Studies show that in boiler systems with no swirl, the distributed temperature sensor may provide information sufficient to predict trends of NOx at the boiler exit. Under Task 3, we investigate a mathematical approach to extrapolation of the temperature distribution within a power plant boiler facility, using a combination of a modified neural network architecture and semigroup theory. The 3D temperature data is furnished by the Penn State Energy Institute using FLUENT. Given a set of empirical data with no analytic expression, we first develop an analytic description and then extend that model along a single axis. Extrapolation

  17. INTELLIGENT MONITORING SYSTEM WITH HIGH TEMPERATURE DISTRIBUTED FIBEROPTIC SENSOR FOR POWER PLANT COMBUSTION PROCESSES

    Energy Technology Data Exchange (ETDEWEB)

    Kwang Y. Lee; Stuart S. Yin; Andre Boheman

    2004-12-26

    The objective of the proposed work is to develop an intelligent distributed fiber optical sensor system for real-time monitoring of high temperature in a boiler furnace in power plants. Of particular interest is the estimation of spatial and temporal distributions of high temperatures within a boiler furnace, which will be essential in assessing and controlling the mechanisms that form and remove pollutants at the source, such as NOx. The basic approach in developing the proposed sensor system is three fold: (1) development of high temperature distributed fiber optical sensor capable of measuring temperatures greater than 2000 C degree with spatial resolution of less than 1 cm; (2) development of distributed parameter system (DPS) models to map the three-dimensional (3D) temperature distribution for the furnace; and (3) development of an intelligent monitoring system for real-time monitoring of the 3D boiler temperature distribution. Under Task 1, improvement was made on the performance of in-fiber grating fabricated in single crystal sapphire fibers, test was performed on the grating performance of single crystal sapphire fiber with new fabrication methods, and the fabricated grating was applied to high temperature sensor. Under Task 2, models obtained from 3-D modeling of the Demonstration Boiler were used to study relationships between temperature and NOx, as the multi-dimensionality of such systems are most comparable with real-life boiler systems. Studies show that in boiler systems with no swirl, the distributed temperature sensor may provide information sufficient to predict trends of NOx at the boiler exit. Under Task 3, we investigate a mathematical approach to extrapolation of the temperature distribution within a power plant boiler facility, using a combination of a modified neural network architecture and semigroup theory. The 3D temperature data is furnished by the Penn State Energy Institute using FLUENT. Given a set of empirical data with no analytic

  18. High-resolution fiber-optic microendoscopy for in situ cellular imaging.

    Science.gov (United States)

    Pierce, Mark; Yu, Dihua; Richards-Kortum, Rebecca

    2011-01-11

    Many biological and clinical studies require the longitudinal study and analysis of morphology and function with cellular level resolution. Traditionally, multiple experiments are run in parallel, with individual samples removed from the study at sequential time points for evaluation by light microscopy. Several intravital techniques have been developed, with confocal, multiphoton, and second harmonic microscopy all demonstrating their ability to be used for imaging in situ. With these systems, however, the required infrastructure is complex and expensive, involving scanning laser systems and complex light sources. Here we present a protocol for the design and assembly of a high-resolution microendoscope which can be built in a day using off-the-shelf components for under US$5,000. The platform offers flexibility in terms of image resolution, field-of-view, and operating wavelength, and we describe how these parameters can be easily modified to meet the specific needs of the end user. We and others have explored the use of the high-resolution microendoscope (HRME) in in vitro cell culture, in excised and living animal tissues, and in human tissues in vivo. Users have reported the use of several different fluorescent contrast agents, including proflavine, benzoporphyrin-derivative monoacid ring A (BPD-MA), and fluoroscein, all of which have received full, or investigational approval from the FDA for use in human subjects. High-resolution microendoscopy, in the form described here, may appeal to a wide range of researchers working in the basic and clinical sciences. The technique offers an effective and economical approach which complements traditional benchtop microscopy, by enabling the user to perform high-resolution, longitudinal imaging in situ.

  19. INTELLIGENT MONITORING SYSTEM WITH HIGH TEMPERATURE DISTRIBUTED FIBEROPTIC SENSOR FOR POWER PLANT COMBUSTION PROCESSES

    Energy Technology Data Exchange (ETDEWEB)

    Kwang Y. Lee; Stuart S. Yin; Andre Boheman

    2003-12-26

    The objective of the proposed work is to develop an intelligent distributed fiber optical sensor system for real-time monitoring of high temperature in a boiler furnace in power plants. Of particular interest is the estimation of spatial and temporal distributions of high temperatures within a boiler furnace, which will be essential in assessing and controlling the mechanisms that form and remove pollutants at the source, such as NOx. The basic approach in developing the proposed sensor system is three fold: (1) development of high temperature distributed fiber optical sensor capable of measuring temperatures greater than 2000 C degree with spatial resolution of less than 1 cm; (2) development of distributed parameter system (DPS) models to map the three-dimensional (3D) temperature distribution for the furnace; and (3) development of an intelligent monitoring system for real-time monitoring of the 3D boiler temperature distribution. Under Task 1, the efforts focused on developing an innovative high temperature distributed fiber optic sensor by fabricating in-fiber gratings in single crystal sapphire fibers. So far, our major accomplishments include: Successfully grown alumina cladding layers on single crystal sapphire fibers, successfully fabricated in-fiber gratings in single crystal sapphire fibers, and successfully developed a high temperature distributed fiber optic sensor. Under Task 2, the emphasis has been on putting into place a computational capability for simulation of combustors. A PC workstation was acquired with dual Xeon processors and sufficient memory to support 3-D calculations. An existing license for Fluent software was expanded to include two PC processes, where the existing license was for a Unix workstation. Under Task 3, intelligent state estimation theory is being developed which will map the set of 1D (located judiciously within a 3D environment) measurement data into a 3D temperature profile. This theory presents a semigroup

  20. Density limits investigation and high density operation in EAST tokamak

    Science.gov (United States)

    Zheng, Xingwei; Li, Jiangang; Hu, Jiansheng; Liu, Haiqing; Jie, Yinxian; Wang, Shouxin; Li, Jiahong; Duan, Yanming; Li, Miaohui; Li, Yongchun; Zhang, Ling; Ye, Yang; Yang, Qingquan; Zhang, Tao; Cheng, Yingjie; Xu, Jichan; Wang, Liang; Xu, Liqing; Zhao, Hailin; Wang, Fudi; Lin, Shiyao; Wu, Bin; Lyu, Bo; Xu, Guosheng; Gao, Xiang; Shi, Tonghui; He, Kaiyang; Lan, Heng; Chu, Nan; Cao, Bin; Sun, Zhen; Zuo, Guizhong; Ren, Jun; Zhuang, Huidong; Li, Changzheng; Yuan, Xiaolin; Yu, Yaowei; Wang, Houyin; Chen, Yue; Wu, Jinhua; EAST Team

    2016-05-01

    Increasing the density in a tokamak is limited by the so-called density limit, which is generally performed as an appearance of disruption causing loss of plasma confinement, or a degradation of high confinement mode which could further lead to a H  →  L transition. The L-mode and H-mode density limit has been investigated in EAST tokamak. Experimental results suggest that density limits could be triggered by either edge cooling or excessive central radiation. The L-mode density limit disruption is generally triggered by edge cooling, which leads to the current profile shrinkage and then destabilizes a 2/1 tearing mode, ultimately resulting in a disruption. The L-mode density limit scaling agrees well with the Greenwald limit in EAST. The observed H-mode density limit in EAST is an operational-space limit with a value of 0.8∼ 0.9{{n}\\text{GW}} . High density H-mode heated by neutral beam injection (NBI) and lower hybrid current drive (LHCD) are analyzed, respectively. The constancy of the edge density gradients in H-mode indicates a critical limit caused perhaps by e.g. ballooning induced transport. The maximum density is accessed at the H  →  L transition which is generally caused by the excessive core radiation due to high Z impurities (Fe, Cu). Operating at a high density (>2.8× {{10}19} {{\\text{m}}-3} ) is favorable for suppressing the beam shine through NBI. High density H-mode up to 5.3× {{10}19}{{\\text{m}}-3}~≤ft(∼ 0.8{{n}\\text{GW}}\\right) could be sustained by 2 MW 4.6 GHz LHCD alone, and its current drive efficiency is studied. Statistics show that good control of impurities and recycling facilitate high density operation. With careful control of these factors, high density up to 0.93{{n}\\text{GW}} stable H-mode operation was carried out heated by 1.7 MW LHCD and 1.9 MW ion cyclotron resonance heating with supersonic molecular beam injection fueling.

  1. Buying Fiber-Optic Networks.

    Science.gov (United States)

    Fickes, Michael

    2003-01-01

    Describes consortia formed by college and university administrators to buy, manage, and maintain their own fiber-optic networks with the goals of cutting costs of leasing fiber-optic cable and planning for the future. Growth capacity is the real advantage of owning fiber-optic systems. (SLD)

  2. Simultaneous fingerprint and high-wavenumber fiber-optic Raman spectroscopy enhances real-time in vivo diagnosis of adenomatous polyps during colonoscopy.

    Science.gov (United States)

    Bergholt, Mads Sylvest; Lin, Kan; Wang, Jianfeng; Zheng, Wei; Xu, Hongzhi; Huang, Qingwen; Ren, Jian-Lin; Ho, Khek Yu; Teh, Ming; Srivastava, Supriya; Wong, Benjamin; Yeoh, Khay Guan; Huang, Zhiwei

    2016-04-01

    Colorectal cancer can be prevented if detected early (e.g., precancerous polyps-adenoma). Endoscopic differential diagnosis of hyperplastic polyps (that have little or no risk of malignant transformation) and adenomas (that have prominent malignant latency) remains an unambiguous clinical challenge. Raman spectroscopy is an optical vibrational technique capable of probing biomolecular changes of tissue associated with neoplastic transformation. This work aims to apply a fiber-optic simultaneous fingerprint (FP) and high wavenumber (HW) Raman spectroscopy technique for real-time in vivo assessment of adenomatous polyps during clinical colonoscopy. We have developed a fiber-optic Raman endoscopic technique capable of simultaneously acquiring both the FP (i.e., 800-1800 cm(-1)) and HW (i.e., 2800-3600 cm(-1)) Raman spectra from colorectal tissue subsurface (Raman spectra were acquired from 50 patients with 17 colorectal polyps during clinical colonoscopy. Prominent Raman spectral differences (p Raman endoscopy provides a diagnostic sensitivity of 90.9% and specificity of 83.3% for differentiating adenoma from hyperplastic polyps, which is superior to either the FP or HW Raman technique alone. This study shows that simultaneous FP/HW Raman spectroscopy technique has the potential to be a clinically powerful tool for improving early diagnosis of adenomatous polyps in vivo during colonoscopic examination. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. Development of a polymer based fiberoptic magnetostrictive metal detector system.

    Science.gov (United States)

    Hua, Wei Shu; Hooks, Joshua Rosenberg; Wu, Wen Jong; Wang, Wei Chih

    2010-10-01

    This paper presents a new metal detector using a fiberoptic magnetostriction sensor. The metal sensor uses a fiber-optic Mach-Zehnder interferometer with a newly developed ferromagnetic polymer as the magnetostrictive sensing material. This polymeric magnetostrictive fiberoptic metal sensor is simple to fabricate, small in size, and resistant to RF interference (which is common in typical electromagnetic type metal detectors). Metal detection is based on disruption of the magnetic flux density across the magnetostriction sensor. In this paper, characteristics of the material being sensed and magnetic properties of the ferromagnetic polymers will be discussed.

  4. High-density lipoprotein cholesterol: How High

    Directory of Open Access Journals (Sweden)

    G Rajagopal

    2012-01-01

    Full Text Available The high-density lipoprotein cholesterol (HDL-C is considered anti-atherogenic good cholesterol. It is involved in reverse transport of lipids. Epidemiological studies have found inverse relationship of HDL-C and coronary heart disease (CHD risk. When grouped according to HDL-C, subjects having HDL-C more than 60 mg/dL had lesser risk of CHD than those having HDL-C of 40-60 mg/dL, who in turn had lesser risk than those who had HDL-C less than 40 mg/dL. No upper limit for beneficial effect of HDL-C on CHD risk has been identified. The goals of treating patients with low HDL-C have not been firmly established. Though many drugs are known to improve HDL-C concentration, statins are proven to improve CHD risk and mortality. Cholesteryl ester transfer protein (CETP is involved in metabolism of HDL-C and its inhibitors are actively being screened for clinical utility. However, final answer is still awaited on CETP-inhibitors.

  5. Highly spatially resolved velocity measurements of a turbulent channel flow by a fiber-optic heterodyne laser-Doppler velocity-profile sensor

    Energy Technology Data Exchange (ETDEWEB)

    Shirai, K.; Pfister, T.; Buettner, L.; Czarske, J. [Dresden University of Technology (TU Dresden), Department of Electrical Engineering and Information Technology, Chair for Measurement and Testing Techniques, Dresden (Germany); Mueller, H. [Physikalisch-Technische Bundesanstalt Braunschweig (PTB), Department 1.4 Gas Flow, Braunschweig (Germany); Becker, S.; Lienhart, H.; Durst, F. [Institute of Fluid Mechanics (LSTM), Friedrich-Alexander-University Erlangen-Nuernberg, Erlangen (Germany)

    2006-03-15

    Velocity measurements with a high spatial resolution are important in turbulent flow research. In this paper, we report on the development of a new fiber-optic laser-Doppler velocity-profile sensor exhibiting a spatial resolution of up to 5 {mu}m and its application to turbulent boundary layers. The sensor developed in the present work employs a frequency-division-multiplexing technique in order to separate two measurement signals from the two fringe systems. Velocity measurements close to zero at the solid wall were realized using heterodyne technique. The use of fiber optics improved a robustness of the sensor. The measurement accuracy of the sensor was experimentally investigated with respect to the spatial resolution and velocity. Universal velocity profile of a turbulent flow was obtained in a fully developed channel flow. Mean and fluctuating velocity are presented with a high spatial resolution. (orig.)

  6. Importing low-density ideas to high-density revitalisation

    DEFF Research Database (Denmark)

    Anrholtz, Jens; Ibsen, Christian Lyhne; Ibsen, Flemming

    2016-01-01

    Why did union officials from a high-union-density country like Denmark choose to import an organising strategy from low-density countries such as the US and the UK? Drawing on in-depth interviews with key union officials and internal documents, the authors of this article argue two key points. Fi...... cherry-pick some elements while leaving fundamental aspects out. The study nevertheless indicates that a lack of coherency and model-fit to Danish industrial relations might hamper the positive effects of the organising strategy....

  7. High Energy Density Capacitors Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Capacitor size and reliability are often limiting factors in pulse power, high speed switching, and power management and distribution (PMAD) systems. T/J...

  8. Cascaded fiber-optic Fabry-Perot interferometers with Vernier effect for highly sensitive measurement of axial strain and magnetic field.

    Science.gov (United States)

    Zhang, Peng; Tang, Ming; Gao, Feng; Zhu, Benpeng; Fu, Songnian; Ouyang, Jun; Shum, Perry Ping; Liu, Deming

    2014-08-11

    We report a highly sensitive fiber-optic sensor based on two cascaded intrinsic fiber Fabry-Perot interferometers (IFFPIs). The cascaded IFFPIs have different free spectral ranges (FSRs) and are formed by a short section of hollow core photonic crystal fiber sandwiched by two single mode fibers. With the superposition of reflective spectrum with different FSRs, the Vernier effect will be generated in the proposed sensor and we found that the strain sensitivity of the proposed sensor can be improved from 1.6 pm/με for a single IFFPI sensor to 47.14 pm/με by employing the Vernier effect. The sensor embed with a metglas ribbon can be also used to measure the magnetic field according to the similar principle. The sensitivity of the magnetic field measurement is achieved to be 71.57 pm/Oe that is significantly larger than the 2.5 pm/Oe for a single IFFPI sensor.

  9. Charging a Battery-Powered Device with a Fiber-Optically Connected Photonic Power System for Achieving High-Voltage Isolation

    Energy Technology Data Exchange (ETDEWEB)

    Lizon, David C [Los Alamos National Laboratory; Gioria, Jack G [Los Alamos National Laboratory; Dale, Gregory E [Los Alamos National Laboratory; Snyder, Hans R [Los Alamos National Laboratory

    2008-01-01

    This paper describes the development and testing of a system to provide isolated power to the cathode-subsystem electronics of an x-ray tube. These components are located at the cathode potential of several hundred kilovolts, requiring a supply of power isolated from this high voltage. In this design a fiber-optically connected photonic power system (PPS) is used to recharge a lithium-ion battery pack, which will subsequently supply power to the cathode-subsystem electronics. The suitability of the commercially available JDSU PPS for this application is evaluated. The output of the ppe converter is characterized. The technical aspects of its use for charging a variety of Li-Ion batteries are discussed. Battery charge protection requirements and safety concerns are also addressed.

  10. Electronic DC transformer with high power density

    NARCIS (Netherlands)

    Pavlovský, M.

    2006-01-01

    This thesis is concerned with the possibilities of increasing the power density of high-power dc-dc converters with galvanic isolation. Three cornerstones for reaching high power densities are identified as: size reduction of passive components, reduction of losses particularly in active components

  11. High regression rate, high density hybrid fuels Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This SBIR program will investigate high energy density novel nanofuels combined with high density binders for use with an N2O oxidizer. Terves has developed...

  12. High energy density lithium batteries

    CERN Document Server

    Aifantis, Katerina E; Kumar, R Vasant

    2010-01-01

    Cell phones, portable computers and other electronic devices crucially depend on reliable, compact yet powerful batteries. Therefore, intensive research is devoted to improving performance and reducing failure rates. Rechargeable lithium-ion batteries promise significant advancement and high application potential for hybrid vehicles, biomedical devices, and everyday appliances. This monograph provides special focus on the methods and approaches for enhancing the performance of next-generation batteries through the use of nanotechnology. Deeper understanding of the mechanisms and strategies is

  13. Fiberoptic metal detector capable of profile detection

    OpenAIRE

    Hua, Wei-Shu; Hooks, Joshua R.; Erwin, Nicholas A.; Wu, Wen-Jong; Wang, Wei-Chih

    2011-01-01

    The purpose of this paper is to develop a novel ferromagnetic polymeric metal detector system by using a fiber-optic Mach-Zehnder interferometer with a newly developed ferromagnetic polymer as the magnetostrictive sensing device. This ferromagnetic polymeric metal detector system is simple to fabricate, small in size, and resistant to RF interference (which is common in typical electromagnetic type metal detectors). Metal detection is made possible by disrupting the magnetic flux density pres...

  14. Density Estimation Trees in High Energy Physics

    CERN Document Server

    Anderlini, Lucio

    2015-01-01

    Density Estimation Trees can play an important role in exploratory data analysis for multidimensional, multi-modal data models of large samples. I briefly discuss the algorithm, a self-optimization technique based on kernel density estimation, and some applications in High Energy Physics.

  15. Fiber-Optic Sensor Facility

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Constructs and evaluates fiber-optic sensors for a variety of measurands. These measurands include acoustic, pressure, magnetic, and electric field as well...

  16. Institute for High Energy Density Science

    Energy Technology Data Exchange (ETDEWEB)

    Wootton, Alan [Univ. of Texas, Austin, TX (United States)

    2017-01-13

    The project objective was for the Institute of High Energy Density Science (IHEDS) at the University of Texas at Austin to help grow the High Energy Density (HED) science community, by connecting academia with the Z Facility (Z) and associated staff at Sandia National Laboratories (SNL). IHEDS was originally motivated by common interests and complementary capabilities at SNL and the University of Texas System (UTX), in 2008.

  17. Strongly Interacting Matter at High Energy Density

    Energy Technology Data Exchange (ETDEWEB)

    McLerran,L.

    2008-09-07

    This lecture concerns the properties of strongly interacting matter (which is described by Quantum Chromodynamics) at very high energy density. I review the properties of matter at high temperature, discussing the deconfinement phase transition. At high baryon density and low temperature, large N{sub c} arguments are developed which suggest that high baryonic density matter is a third form of matter, Quarkyonic Matter, that is distinct from confined hadronic matter and deconfined matter. I finally discuss the Color Glass Condensate which controls the high energy limit of QCD, and forms the low x part of a hadron wavefunction. The Glasma is introduced as matter formed by the Color Glass Condensate which eventually thermalizes into a Quark Gluon Plasma.

  18. Spin polarization in high density quark matter

    DEFF Research Database (Denmark)

    Bohr, Henrik; Panda, Prafulla K.; Providênci, Constanca

    2013-01-01

    We investigate the occurrence of a ferromagnetic phase transition in high density hadronic matter (e.g., in the interior of a neutron star). This could be induced by a four-fermion interaction analogous to the one which is responsible for chiral symmetry breaking in the Nambu-Jona-Lasinio model......, to which it is related through a Fierz transformation. Flavor SU(2) and flavor SU(3) quark matter are considered. A second-order phase transition is predicted at densities about 5 times the normal nuclear matter density. It is also found that in flavor SU(3) quark matter, a first-order transition from...

  19. The high density Z-pinch

    Energy Technology Data Exchange (ETDEWEB)

    McCall, G.H.

    1988-01-01

    During the past few years techniques have been developed for producing pinches in solid deuterium. The conditions which exist in these plasmas are quiet different from those produced earlier. The pinch is formed from a fiber of solid deuterium rather than from a low density gas, and the current is driven by a low impedance, high voltage pulse generator. Because of the high initial density, it is not necessary to compress the pinch to reach thermonuclear conditions, and the confinement time required for energy production is much shorter than for a gas. The experimental results, which have been verified by experiments performed at higher current were quite surprising and encouraging. The pinch appeared to be stable for a time much longer than the Alfven radial transit time. In this paper, however, I argue that the pinch is not strictly stable, but it does not appear to disassemble in a catastrophic fashion. It appears that there may be a distinction between stability and confinement in the high density pinch. In the discussion below I will present the status of the high density Z-pinch experiments at laboratories around the world, and I will describe some of the calculational and experimental results. I will confine my remarks to recent work on the high density pinch. 17 refs. 10 figs.

  20. A high-sensitivity fiber-optic evanescent wave sensor with a three-layer structure composed of Canada balsam doped with GeO2.

    Science.gov (United States)

    Zhong, Nianbing; Zhao, Mingfu; Zhong, Lianchao; Liao, Qiang; Zhu, Xun; Luo, Binbin; Li, Yishan

    2016-11-15

    In this paper, we present a high-sensitivity polymer fiber-optic evanescent wave (FOEW) sensor with a three-layer structure that includes bottom, inter-, and surface layers in the sensing region. The bottom layer and inter-layer are POFs composed of standard cladding and the core of the plastic optical fiber, and the surface layer is made of dilute Canada balsam in xylene doped with GeO2. We examine the morphology of the doped GeO2, the refractive index and composition of the surface layer and the surface luminous properties of the sensing region. We investigate the effects of the content and morphology of the GeO2 particles on the sensitivity of the FOEW sensors by using glucose solutions. In addition, we examine the response of sensors incubated with staphylococcal protein A plus mouse IgG isotype to goat anti-mouse IgG solutions. Results indicate very good sensitivity of the three-layer FOEW sensor, which showed a 3.91-fold improvement in the detection of the target antibody relative to a conventional sensor with a core-cladding structure, and the novel sensor showed a lower limit of detection of 0.2ng/l and a response time around 320s. The application of this high-sensitivity FOEW sensor can be extended to biodefense, disease diagnosis, biomedical and biochemical analysis.

  1. Development and Beam-Shape Analysis of an Integrated Fiber-Optic Confocal Probe for High-Precision Central Thickness Measurement of Small-Radius Lenses

    Directory of Open Access Journals (Sweden)

    Boonsong Sutapun

    2015-04-01

    Full Text Available This work describes a new design of a fiber-optic confocal probe suitable for measuring the central thicknesses of small-radius optical lenses or similar objects. The proposed confocal probe utilizes an integrated camera that functions as a shape-encoded position-sensing device. The confocal signal for thickness measurement and beam-shape data for off-axis measurement can be simultaneously acquired using the proposed probe. Placing the probe’s focal point off-center relative to a sample’s vertex produces a non-circular image at the camera’s image plane that closely resembles an ellipse for small displacements. We were able to precisely position the confocal probe’s focal point relative to the vertex point of a ball lens with a radius of 2.5 mm, with a lateral resolution of 1.2 µm. The reflected beam shape based on partial blocking by an aperture was analyzed and verified experimentally. The proposed confocal probe offers a low-cost, high-precision technique, an alternative to a high-cost three-dimensional surface profiler, for tight quality control of small optical lenses during the manufacturing process.

  2. High Density Metamaterials for Visible Light

    Science.gov (United States)

    2016-11-28

    Split Ring Resonator Metamaterials with Fundamental Magnetic Resonance in the Middle Visible Spectrum,” Adv. Opt. Mater., vol. 2, no. 3, pp. 280–285...AFRL-AFOSR-JP-TR-2016-0097 High density metamaterials for visible light Dao Hua Zhang NANYANG TECHNOLOGICAL UNIVERSITY Final Report 11/28/2016...COVERED (From - To)  16 Jul 2014 to 15 Jul 2016 4. TITLE AND SUBTITLE High density metamaterials for visible light 5a.  CONTRACT NUMBER 5b.  GRANT

  3. A quarksonic matter at high isospin density

    CERN Document Server

    Cao, Gaoqing; Huang, Xu-Guang

    2016-01-01

    Analogous to the quarkyonic matter at high baryon density in which the quark Fermi seas and the baryonic excitations coexist, it is argued that a "quarksonic matter" phase appears at high isospin density where the quark (antiquark) Fermi seas and the mesonic excitations coexist. We explore this phase in detail in both large $N_c$ and asymptotically free limits: In large $N_c$ limit, we sketch a phase diagram for the quarksonic matter. In the asymptotically free limit, we study the pion superfluidity and thermodynamics of the quarksonic matter by using both perturbative calculations and effective model.

  4. High energy density in multisoliton collisions

    Science.gov (United States)

    Saadatmand, Danial; Dmitriev, Sergey V.; Kevrekidis, Panayotis G.

    2015-09-01

    Solitons are very effective in transporting energy over great distances and collisions between them can produce high energy density spots of relevance to phase transformations, energy localization and defect formation among others. It is then important to study how energy density accumulation scales in multisoliton collisions. In this study, we demonstrate that the maximal energy density that can be achieved in collision of N slowly moving kinks and antikinks in the integrable sine-Gordon field, remarkably, is proportional to N2, while the total energy of the system is proportional to N . This maximal energy density can be achieved only if the difference between the number of colliding kinks and antikinks is minimal, i.e., is equal to 0 for even N and 1 for odd N and if the pattern involves an alternating array of kinks and antikinks. Interestingly, for odd (even) N the maximal energy density appears in the form of potential (kinetic) energy, while kinetic (potential) energy is equal to zero. The results of the present study rely on the analysis of the exact multisoliton solutions for N =1 ,2 , and 3 and on the numerical simulation results for N =4 ,5 ,6 , and 7. The effect of weak Hamiltonian and non-Hamiltonian perturbations on the maximal energy density in multikink collisions is also discussed as well as that of the collision relative phase. Based on these results one can speculate that the soliton collisions in the sine-Gordon field can, in principle, controllably produce very high energy density. This can have important consequences for many physical phenomena described by the Klein-Gordon equations.

  5. Supernovae and high density nuclear matter

    Energy Technology Data Exchange (ETDEWEB)

    Kahana, S.

    1986-01-01

    The role of the nuclear equation of state (EOS) in producing prompt supernova explosions is examined. Results of calculations of Baron, Cooperstein, and Kahana incorporating general relativity and a new high density EOS are presented, and the relevance of these calculations to laboratory experiments with heavy ions considered. 31 refs., 6 figs., 2 tabs.

  6. High Gluon Densities in Heavy Ions Collisions

    CERN Document Server

    Blaizot, Jean-Paul

    2016-01-01

    The early stages of heavy ion collisions are dominated by high density systems of gluons that carry each a small fraction $x$ of the momenta of the colliding nucleons. A distinguishing feature of such systems is the phenomenon of "saturation" which tames the expected growth of the gluon density as the energy of the collision increases. The onset of saturation occurs at a particular transverse momentum scale, the "saturation momentum", that emerges dynamically and that marks the onset of non-linear gluon interactions. At high energy, and for large nuclei, the saturation momentum is large compared to the typical hadronic scale, making high density gluons amenable to a description with weak coupling techniques. This paper reviews some of the challenges faced in the study of such dense systems of small $x$ gluons, and of the progress made in addressing them. The focus is on conceptual issues, and the presentation is both pedagogical, and critical. Examples where high gluon density could play a visible role in hea...

  7. High Density GEOSAT/GM Altimeter Data

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The high density Geosat/GM altimeter data south of 30 S have finally arrived. In addition, ERS-1 has completed more than 6 cycles of its 35-day repeat track. These...

  8. Two-color QCD at high density

    Energy Technology Data Exchange (ETDEWEB)

    Boz, Tamer; Skullerud, Jon-Ivar [Department of Mathematical Physics, Maynooth University, Maynooth, Co. Kildare (Ireland); Centre for the Subatomic Structure of Matter, Adelaide University, Adelaide, SA 5005 (Australia); Giudice, Pietro [Universität Münster, Institut für Theoretische Physik, Münster (Germany); Hands, Simon [Department of Physics, College of Science, Swansea University, Swansea (United Kingdom); Williams, Anthony G. [Centre for the Subatomic Structure of Matter, Adelaide University, Adelaide, SA 5005 (Australia)

    2016-01-22

    QCD at high chemical potential has interesting properties such as deconfinement of quarks. Two-color QCD, which enables numerical simulations on the lattice, constitutes a laboratory to study QCD at high chemical potential. Among the interesting properties of two-color QCD at high density is the diquark condensation, for which we present recent results obtained on a finer lattice compared to previous studies. The quark propagator in two-color QCD at non-zero chemical potential is referred to as the Gor’kov propagator. We express the Gor’kov propagator in terms of form factors and present recent lattice simulation results.

  9. Fiberoptic metal detector capable of profile detection

    Science.gov (United States)

    Hua, Wei-Shu; Hooks, Joshua R.; Erwin, Nicholas A.; Wu, Wen-Jong; Wang, Wei-Chih

    2011-04-01

    The purpose of this paper is to develop a novel ferromagnetic polymeric metal detector system by using a fiber-optic Mach-Zehnder interferometer with a newly developed ferromagnetic polymer as the magnetostrictive sensing device. This ferromagnetic polymeric metal detector system is simple to fabricate, small in size, and resistant to RF interference (which is common in typical electromagnetic type metal detectors). Metal detection is made possible by disrupting the magnetic flux density present on the magnetostrictive sensor. This paper discusses the magnetic properties of the ferromagnetic polymers. In addition, the preliminary results of successful sensing of different geometrical metal shapes will be discussed.

  10. Fiberoptic metal detector capable of profile detection.

    Science.gov (United States)

    Hua, Wei-Shu; Hooks, Joshua R; Erwin, Nicholas A; Wu, Wen-Jong; Wang, Wei-Chih

    2011-03-31

    The purpose of this paper is to develop a novel ferromagnetic polymeric metal detector system by using a fiber-optic Mach-Zehnder interferometer with a newly developed ferromagnetic polymer as the magnetostrictive sensing device. This ferromagnetic polymeric metal detector system is simple to fabricate, small in size, and resistant to RF interference (which is common in typical electromagnetic type metal detectors). Metal detection is made possible by disrupting the magnetic flux density present on the magnetostrictive sensor. This paper discusses the magnetic properties of the ferromagnetic polymers. In addition, the preliminary results of successful sensing of different geometrical metal shapes will be discussed.

  11. Method of high-density foil fabrication

    Energy Technology Data Exchange (ETDEWEB)

    Blue, Craig A.; Sikka, Vinod K.; Ohriner, Evan K.

    2003-12-16

    A method for preparing flat foils having a high density includes the steps of mixing a powdered material with a binder to form a green sheet. The green sheet is exposed to a high intensity radiative source adapted to emit radiation of wavelengths corresponding to an absorption spectrum of the powdered material. The surface of the green sheet is heated while a lower sub-surface temperature is maintained. An apparatus for preparing a foil from a green sheet using a radiation source is also disclosed.

  12. HIGH DENSITY QCD WITH HEAVY-IONS

    CERN Multimedia

    The Addendum 1 to Volume 2 of the CMS Physics TDR has been published The Heavy-Ion analysis group completed the writing of a TDR summarizing the CMS plans in using heavy ion collisions to study high density QCD. The document was submitted to the LHCC in March and presented in the Open Session of the LHCC on May 9th. The study of heavy-ion physics at the LHC is promising to be very exciting. LHC will open a new energy frontier in ultra-relativistic heavy-ion physics. The collision energy of heavy nuclei at sNN = 5.5 TeV will be thirty times larger than what is presently available at RHIC. We will certainly probe quark and gluon matter at unprecedented values of energy density. The prime goal of this research programme is to study the fundamental theory of the strong interaction - Quantum Chromodynamics (QCD) - in extreme conditions of temperature, density and parton momentum fraction (low-x). Such studies, with impressive experimental and theoretical advances in recent years thanks to the wealth of high-qua...

  13. High Spectral Density Optical Communication Technologies

    CERN Document Server

    Nakazawa, Masataka; Miyazaki, Tetsuya

    2010-01-01

    The latest hot topics of high-spectral density optical communication systems using digital coherent optical fibre communication technologies are covered by this book. History and meaning of a "renaissance" of the technology, requirements to the Peta-bit/s class "new generation network" are also covered in the first part of this book. The main topics treated are electronic and optical devices, digital signal processing including forward error correction, modulation formats as well as transmission and application systems. The book serves as a reference to researchers and engineers.

  14. Beyond the local density approximation : improving density functional theory for high energy density physics applications.

    Energy Technology Data Exchange (ETDEWEB)

    Mattsson, Ann Elisabet; Modine, Normand Arthur; Desjarlais, Michael Paul; Muller, Richard Partain; Sears, Mark P.; Wright, Alan Francis

    2006-11-01

    A finite temperature version of 'exact-exchange' density functional theory (EXX) has been implemented in Sandia's Socorro code. The method uses the optimized effective potential (OEP) formalism and an efficient gradient-based iterative minimization of the energy. The derivation of the gradient is based on the density matrix, simplifying the extension to finite temperatures. A stand-alone all-electron exact-exchange capability has been developed for testing exact exchange and compatible correlation functionals on small systems. Calculations of eigenvalues for the helium atom, beryllium atom, and the hydrogen molecule are reported, showing excellent agreement with highly converged quantumMonte Carlo calculations. Several approaches to the generation of pseudopotentials for use in EXX calculations have been examined and are discussed. The difficult problem of finding a correlation functional compatible with EXX has been studied and some initial findings are reported.

  15. Recycling of irradiated high-density polyethylene

    Science.gov (United States)

    Navratil, J.; Manas, M.; Mizera, A.; Bednarik, M.; Stanek, M.; Danek, M.

    2015-01-01

    Radiation crosslinking of high-density polyethylene (HDPE) is a well-recognized modification of improving basic material characteristics. This research paper deals with the utilization of electron beam irradiated HDPE (HDPEx) after the end of its lifetime. Powder of recycled HDPEx (irradiation dose 165 kGy) was used as a filler into powder of virgin low-density polyethylene (LDPE) in concentrations ranging from 10% to 60%. The effect of the filler on processability and mechanical behavior of the resulting mixtures was investigated. The results indicate that the processability, as well as mechanical behavior, highly depends on the amount of the filler. Melt flow index dropped from 13.7 to 0.8 g/10 min comparing the lowest and the highest concentration; however, the higher shear rate the lower difference between each concentration. Toughness and hardness, on the other hand, grew with increasing addition of the recycled HDPEx. Elastic modulus increased from 254 to 450 MPa and material hardness increased from 53 to 59 ShD. These results indicate resolving the problem of further recycling of irradiated polymer materials while taking advantage of the improved mechanical properties.

  16. High Energy Density aluminum/oxygen cell

    Science.gov (United States)

    Rudd, E. J.; Gibbons, D. W.

    An alternative to a secondary battery as the power source for vehicle propulsion is a fuel cell, an example of which is the metal/air cell using metals such as aluminum, zinc, or iron. Aluminum is a particularly attractive candidate, with high energy and power densities, environmentally acceptable and having a large, established industrial base for production and distribution. An aluminum/oxygen system is currently under development for a prototype unmanned, undersea vehicle (UUV) for the US navy and recent work has focussed upon low corrosion aluminum alloys, and an electrolyte management system for processing the by-products of the energy-producing reactions. This paper summarizes the progress made in both areas. Anode materials capable of providing high utilization factors over current densities ranging from 5 to 150 mA/cm 2 have been identified, such materials being essential to realize mission life for the UUV. With respect to the electrolyte management system, a filter/precipitator unit has been successfully operated for over 250 h in a large scale, half-cell system.

  17. Fiber-optic flow sensors for high-temperature environment operation up to 800°C.

    Science.gov (United States)

    Chen, Rongzhang; Yan, Aidong; Wang, Qingqing; Chen, Kevin P

    2014-07-01

    This Letter presents an all-optical high-temperature flow sensor based on hot-wire anemometry. High-attenuation fibers (HAFs) were used as the heating elements. High-temperature-stable regenerated fiber Bragg gratings were inscribed in HAFs and in standard telecom fibers as temperature sensors. Using in-fiber light as both the heating power source and the interrogation light source, regenerative fiber Bragg grating sensors were used to gauge the heat transfer from an optically powered heating element induced by the gas flow. Reliable gas flow measurements were demonstrated between 0.066  m/s and 0.66  m/s from the room temperature to 800°C. This Letter presents a compact, low-cost, and multiflexible approach to measure gas flow for high-temperature harsh environments.

  18. Fiber-optic Michelson interferometer with high sensitivity based on a liquid-filled photonic crystal fiber

    Science.gov (United States)

    Hsu, Jui-Ming; Horng, Jing-Shyang; Hsu, Chia-Ling; Lee, Cheng-Ling

    2014-11-01

    This study proposes an ultracompact and highly sensitive liquid-filled photonic crystal fiber Michelson interferometer (LF-PCFMI) based on material dispersion engineering. Numerical simulations and experimental measurements are performed in the work, and both of their results show that the temperature sensitivity can be more greatly improved than those of conventional photonic crystal fiber interferometers (PCFIs). The experimental results indicate that a very high sensitivity with interference wavelength shifts of almost 27 nm within temperature variation of 5 °C has been achieved by the configuration. Numerical analysis for the proposed LF-PCFMI also exhibits a good agreement with the results of the experimental measurements.

  19. High-Frequency Fiber-Optic Ultrasonic Sensor Using Air Micro-Bubble for Imaging of Seismic Physical Models

    Directory of Open Access Journals (Sweden)

    Tingting Gang

    2016-12-01

    Full Text Available A micro-fiber-optic Fabry-Perot interferometer (FPI is proposed and demonstrated experimentally for ultrasonic imaging of seismic physical models. The device consists of a micro-bubble followed by the end of a single-mode fiber (SMF. The micro-structure is formed by the discharging operation on a short segment of hollow-core fiber (HCF that is spliced to the SMF. This micro FPI is sensitive to ultrasonic waves (UWs, especially to the high-frequency (up to 10 MHz UW, thanks to its ultra-thin cavity wall and micro-diameter. A side-band filter technology is employed for the UW interrogation, and then the high signal-to-noise ratio (SNR UW signal is achieved. Eventually the sensor is used for lateral imaging of the physical model by scanning UW detection and two-dimensional signal reconstruction.

  20. Ground state of high-density matter

    Science.gov (United States)

    Copeland, ED; Kolb, Edward W.; Lee, Kimyeong

    1988-01-01

    It is shown that if an upper bound to the false vacuum energy of the electroweak Higgs potential is satisfied, the true ground state of high-density matter is not nuclear matter, or even strange-quark matter, but rather a non-topological soliton where the electroweak symmetry is exact and the fermions are massless. This possibility is examined in the standard SU(3) sub C tensor product SU(2) sub L tensor product U(1) sub Y model. The bound to the false vacuum energy is satisfied only for a narrow range of the Higgs boson masses in the minimal electroweak model (within about 10 eV of its minimum allowed value of 6.6 GeV) and a somewhat wider range for electroweak models with a non-minimal Higgs sector.

  1. Nanotechnology for Synthetic High Density Lipoproteins

    Science.gov (United States)

    Luthi, Andrea J.; Patel, Pinal C.; Ko, Caroline H.; Mutharasan, R. Kannan; Mirkin, Chad A.; Thaxton, C. Shad

    2014-01-01

    Atherosclerosis is the disease mechanism responsible for coronary heart disease (CHD), the leading cause of death worldwide. One strategy to combat atherosclerosis is to increase the amount of circulating high density lipoproteins (HDL), which transport cholesterol from peripheral tissues to the liver for excretion. The process, known as reverse cholesterol transport, is thought to be one of the main reasons for the significant inverse correlation observed between HDL blood levels and the development of CHD. This article highlights the most common strategies for treating atherosclerosis using HDL. We further detail potential treatment opportunities that utilize nanotechnology to increase the amount of HDL in circulation. The synthesis of biomimetic HDL nanostructures that replicate the chemical and physical properties of natural HDL provides novel materials for investigating the structure-function relationships of HDL and for potential new therapeutics to combat CHD. PMID:21087901

  2. High power density carbonate fuel cell

    Energy Technology Data Exchange (ETDEWEB)

    Yuh, C.; Johnsen, R.; Doyon, J.; Allen, J. [Energy Research Corp., Danbury, CT (United States)

    1996-12-31

    Carbonate fuel cell is a highly efficient and environmentally clean source of power generation. Many organizations worldwide are actively pursuing the development of the technology. Field demonstration of multi-MW size power plant has been initiated in 1996, a step toward commercialization before the turn of the century, Energy Research Corporation (ERC) is planning to introduce a 2.85MW commercial fuel cell power plant with an efficiency of 58%, which is quite attractive for distributed power generation. However, to further expand competitive edge over alternative systems and to achieve wider market penetration, ERC is exploring advanced carbonate fuel cells having significantly higher power densities. A more compact power plant would also stimulate interest in new markets such as ships and submarines where space limitations exist. The activities focused on reducing cell polarization and internal resistance as well as on advanced thin cell components.

  3. Impact of fiber-optic laryngoscopy on the weaning process from mechanical ventilation in high-risk patients for postextubation stridor

    Science.gov (United States)

    Lemyze, Malcolm; Durville, Emmanuelle; Meddour, Mehdi; Jonard, Marie; Temime, Johanna; Barailler, Stéphanie; Thevenin, Didier; Mallat, Jihad

    2017-01-01

    Abstract The objective of this study was to assess the impact of fiber-optic laryngoscopy (FOL) on the weaning process from mechanical ventilation in critically ill patients with a positive cuff leak test (CLT) as compared with the current recommended strategy based on corticosteroids. In this prospective observational pilot study conducted over a 1-year period in a 15-bed ICU, CLT was systematically performed before extubation in all intubated patients having passed a spontaneous breathing trial (SBT). After the endotracheal tube cuff was deflated, cuff leak volume (CLVol) was assessed during assisted controlled ventilation. When CLT was positive (CLVol < 110 mL), patients either were evaluated using FOL by our half-time FOL-practitioner when present, or received corticosteroids. Among the 233 patients included, 34 (14.6%) had a positive CLT that hampered extubation. Seventeen were treated by corticosteroids and 17 were evaluated by FOL. In the corticosteroids group, the CLVol was still <110 mL at 24 hours in 9 patients (53%). Corticosteroids strategy merely prolonged the total duration of mechanical ventilation (7 [4–11] vs 4 [2–6] days, P = 0.01) by increasing the time between successful SBT and the moment when extubation was effectively achieved (30 [24–60] vs 1.5 [1–2] hours, P < 0.001). This resulted in 2 self-extubations (12%) and 9 FOL-guided extubations (53%) in the corticosteroids group. Massive swelling of the arytenoids was the most common feature shown by FOL. The patients evaluated by FOL who exhibited the thin anterior V-shaped opening of the vocal cords—the V sign—(n = 26, 100%) were immediately extubated without any stridor or respiratory failure afterward. In this pilot study, a FOL-based extubation strategy was feasible and reliable, and significantly reduced the duration of mechanical ventilation in patients with a positive CLT. We describe the “V sign” of FOL that safely allows a successful prompt extubation

  4. Feasibility of Ultra-Thin Fiber-Optic Dosimeters for Radiotherapy Dosimetry

    Directory of Open Access Journals (Sweden)

    Bongsoo Lee

    2015-11-01

    Full Text Available In this study, prototype ultra-thin fiber-optic dosimeters were fabricated using organic scintillators, wavelength shifting fibers, and plastic optical fibers. The sensor probes of the ultra-thin fiber-optic dosimeters consisted of very thin organic scintillators with thicknesses of 100, 150 and 200 μm. These types of sensors cannot only be used to measure skin or surface doses but also provide depth dose measurements with high spatial resolution. With the ultra-thin fiber-optic dosimeters, surface doses for gamma rays generated from a Co-60 therapy machine were measured. Additionally, percentage depth doses in the build-up regions were obtained by using the ultra-thin fiber-optic dosimeters, and the results were compared with those of external beam therapy films and a conventional fiber-optic dosimeter.

  5. Abnormal high density lipoproteins in cerebrotendinous xanthomatosis

    Energy Technology Data Exchange (ETDEWEB)

    Shore, V. (Lawrence Livermore Lab., CA); Salen, G.; Cheng, F.W.; Forte, T.; Shefer, S.; Tint, G.S.

    1981-11-01

    The plasma lipoprotein profiles and high density lipoproteins (HDL) were characterized in patients with the genetic disease cerebrotendinous xanthomatosis (CTX). The mean HDL-cholesterol concentration in the CTX plasmas was 14.5 +/- 3.2 mg/dl, about one-third the normal value. The low HDL-cholesterol reflects a low concentration and an abnormal lipid composition of the plasma HDL. Relative to normal HDL, the cholesteryl esters are low, free cholesterol and phospholipids essentially normal, and triglycerides increased. The ratio of apoprotein (apo) to total cholesterol in the HDL of CTX was two to three times greater than normal. In the CTX HDL, the ratio of apoAI to apoAII was high, the proportion of apoC low, and a normally minor form of apoAI increased relative to other forms. The HDL in electron micrographs appeared normal morphologically and in particle size. The adnormalities in lipoprotein distribution profiles and composition of the plasma HDL result from metabolic defects that are not understood but may be linked to the genetic defect in bile acid synthesis in CTX. As a consequence, it is probable that the normal functions of the HDL, possibly including modulation of LDL-cholesterol uptake and the removal of excess cholesterol from peripheral tissues, are perturbed significantly in this disease.

  6. Adaptive Holographic Fiber-Optic Interferometer

    Science.gov (United States)

    Kozhevnikov, Nikolai M.; Lipovskaya, Margarita J.

    1990-04-01

    Interaction of phase-modulated light beams in photorefractive local inertial responce media was analysed. Interaction of this type allows to registrate phase-modulated signals adaptively under low frequency phase disturbtion. The experiments on multimode fiber-optic interferometer with demodulation element based on photorefractive bacteriorhodopsin-doped polimer film are described. As the writing of dynamic phase hologram is an inertial process the signal fluctuations with the frequencies up to 100 Hz can be canceled. The hologram efficiencies are enough to registrate high frequency phase shifts ~10-4 radn.

  7. High Energy Density Capacitors for Pulsed Power Applications

    Science.gov (United States)

    2009-07-01

    high energy density energy storage capacitors. High efficency capacitors are available with energy densities as high as 3 J/cc for 1000 shots or...GENERAL ATOMICS ENERGY PRODUCTS Engineering Bulletin HIGH ENERGY DENSITY CAPACITORS FOR PULSED POWER APPLICATIONS Fred MacDougall, Joel...00-2009 4. TITLE AND SUBTITLE High Energy Density Capacitors for Pulsed Power Applications 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM

  8. Dignostic Yield of Fiberoptic Bronchoscopy in a Teaching Hospital

    Directory of Open Access Journals (Sweden)

    Rajinder Singh

    2008-10-01

    Full Text Available Fiberoptic bronchoscopy is minimally invasive procedure which can be performed on outpatient basis.Thestudy is a reterospective review of the data at a tertiary center and compares the diganostic yield of thepatients (n=720, who underwent FB at our pulmonary unit with the data from international centers. Thediagnostic yield of the FB was high(70% with good selection of the patients and growth was the mostcommon finding followed by infections.FB was normal in 218(30% patients. Flexible fiberoptic bronchoscopyis a useful diagnostic tool with a low rate of complications. The diagnostic yield in our institution is alsmostsimilar to that reported in other series.

  9. Nanobiotechnology applications of reconstituted high density lipoprotein.

    Science.gov (United States)

    Ryan, Robert O

    2010-12-01

    High-density lipoprotein (HDL) plays a fundamental role in the Reverse Cholesterol Transport pathway. Prior to maturation, nascent HDL exist as disk-shaped phospholipid bilayers whose perimeter is stabilized by amphipathic apolipoproteins. Methods have been developed to generate reconstituted (rHDL) in vitro and these particles have been used in a variety of novel ways. To differentiate between physiological HDL particles and non-natural rHDL that have been engineered to possess additional components/functions, the term nanodisk (ND) is used. In this review, various applications of ND technology are described, such as their use as miniature membranes for solubilization and characterization of integral membrane proteins in a native like conformation. In other work, ND harboring hydrophobic biomolecules/drugs have been generated and used as transport/delivery vehicles. In vitro and in vivo studies show that drug loaded ND are stable and possess potent biological activity. A third application of ND is their use as a platform for incorporation of amphiphilic chelators of contrast agents, such as gadolinium, used in magnetic resonance imaging. Thus, it is demonstrated that the basic building block of plasma HDL can be repurposed for alternate functions.

  10. Photovoltaic retinal prosthesis with high pixel density

    Science.gov (United States)

    Mathieson, Keith; Loudin, James; Goetz, Georges; Huie, Philip; Wang, Lele; Kamins, Theodore I.; Galambos, Ludwig; Smith, Richard; Harris, James S.; Sher, Alexander; Palanker, Daniel

    2012-06-01

    Retinal degenerative diseases lead to blindness due to loss of the `image capturing' photoreceptors, while neurons in the `image-processing' inner retinal layers are relatively well preserved. Electronic retinal prostheses seek to restore sight by electrically stimulating the surviving neurons. Most implants are powered through inductive coils, requiring complex surgical methods to implant the coil-decoder-cable-array systems that deliver energy to stimulating electrodes via intraocular cables. We present a photovoltaic subretinal prosthesis, in which silicon photodiodes in each pixel receive power and data directly through pulsed near-infrared illumination and electrically stimulate neurons. Stimulation is produced in normal and degenerate rat retinas, with pulse durations of 0.5-4 ms, and threshold peak irradiances of 0.2-10 mW mm-2, two orders of magnitude below the ocular safety limit. Neural responses were elicited by illuminating a single 70 µm bipolar pixel, demonstrating the possibility of a fully integrated photovoltaic retinal prosthesis with high pixel density.

  11. Galaxy interactions II: High density environments

    CERN Document Server

    Alonso, Sol; Padilla, Nelson; Lambas, Diego G

    2011-01-01

    With the aim to assess the role of dense environments in galaxy interactions, properties we present an analysis of close galaxy pairs in groups and clusters, obtained from the Sloan Digital Sky Survey Data Release 7 (SDSS-DR7). We identified pairs that reside in groups by cross-correlating the total galaxy pair catalogue with the SDSS-DR7 group catalogue from Zapata et al. (2009). We classify pair galaxies according to the intensity of interaction. We analysed the effect of high density environments on different classes of galaxy-galaxy interactions and we have also studied the impact of the group global environment on pair galaxies. We find that galaxy pairs are more concentrated towards the group centres with respect to the other group galaxy members, and disturbed pairs show a preference to contain the brightest galaxy in the groups. The color-magnitude relation exhibits significant differences between pair galaxies and the control sample, consisting in color tails with a clear excess of extremely blue and...

  12. Strangeness production in high density baryon matter

    CERN Document Server

    Ganz, R E

    1999-01-01

    Strangeness production in heavy-ion collisions, when compared to proton proton collisions, is potentially a sensitive probe for collective energy deposition and therefore for reaction mechanisms in general. It may therefore provide insight into possible QGP formation in dense nuclear matter. To establish an understanding of the observed yields, a systematic study of high density baryon matter at different beam energies is essential. This might also reveal possible discontinuities in the energy dependence of the reaction mechanism. We present preliminary results for kaon production in Au+Au collisions at beam kinetic energies of 6, 8, and 10.7 GeV/u obtained by the E917 experiment at the AGS (BNL). These measurements complement those carried out by the E866 collaboration at 2, 4, and 10.7 GeV/u with a significantly enlarged data sample. In both experiments a large range of rapidities was covered by taking data at different angular settings of the magnetic spectrometer.

  13. High-density electroencephalography developmental neurophysiological trajectories.

    Science.gov (United States)

    Dan, Bernard; Pelc, Karine; Cebolla, Ana M; Cheron, Guy

    2015-04-01

    Efforts to document early changes in the developing brain have resulted in the construction of increasingly accurate structural images based on magnetic resonance imaging (MRI) in newborn infants. Tractography diagrams obtained through diffusion tensor imaging have focused on white matter microstructure, with particular emphasis on neuronal connectivity at the level of fibre tract systems. Electroencephalography (EEG) provides a complementary approach with more direct access to brain electrical activity. Its temporal resolution is excellent, and its spatial resolution can be enhanced to physiologically relevant levels, through the combination of high-density recordings (e.g. by using 64 channels in newborn infants) and mathematical models (e.g. inverse modelling computation), to identify generators of different oscillation bands and synchrony patterns. The integration of functional and structural topography of the neonatal brain provides insights into typical brain organization, and the deviations seen in particular contexts, for example the effect of hypoxic-ischaemic insult in terms of damage, eventual reorganization, and functional changes. Endophenotypes can then be used for pathophysiological reasoning, management planning, and outcome measurements, and allow a longitudinal approach to individual developmental trajectories. © The Authors. Journal compilation © 2015 Mac Keith Press.

  14. 14 CFR 93.123 - High density traffic airports.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false High density traffic airports. 93.123... (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES High Density Traffic Airports § 93.123 High density traffic airports. (a) Each of the following airports is designated as a...

  15. High-altitude atomic nitrogen densities

    Science.gov (United States)

    Oran, E. S.; Strobel, D. F.; Mauersberger, K.

    1978-01-01

    Theoretical calculations of the seasonal and diurnal variations of atomic nitrogen are compared with measurements made by the open source neutral mass spectrometer on the AE-C satellite. With the simultaneous measurements of molecular nitrogen and atomic oxygen densities as input, model calculations of odd nitrogen densities predict the same trends in atomic nitrogen as those observed. From these comparisons it is inferred that horizontal transport significantly reduces the diurnal variation of atomic nitrogen. Estimates are given of the sensitivity of atomic nitrogen densities to variations in the photoelectron flux, the neutral temperatures, and the neutral winds.

  16. Alternative Approaches to High Energy Density Fusion

    Science.gov (United States)

    Hammer, J.

    2016-10-01

    This paper explores selected approaches to High Energy Density (HED) fusion, beginning with discussion of ignition requirements at the National Ignition Facility (NIF). The needed improvements to achieve ignition are closely tied to the ability to concentrate energy in the implosion, manifested in the stagnation pressure, Pstag. The energy that must be assembled in the imploded state to ignite varies roughly as Pstag-2, so among other requirements, there is a premium on reaching higher Pstag to achieve ignition with the available laser energy. The U.S. inertial confinement fusion program (ICF) is pursuing higher Pstag on NIF through improvements to capsule stability and symmetry. One can argue that recent experiments place an approximate upper bound on the ultimate ignition energy requirement. Scaling the implosions consistently in spatial, temporal and energy scales shows that implosions of the demonstrated quality ignite robustly at 9-15 times the current energy of NIF. While lasers are unlikely to reach that bounding energy, it appears that pulsed-power sources could plausibly do so, giving a range of paths forward for ICF depending on success in improving energy concentration. In this paper, I show the scaling arguments then discuss topics from my own involvement in HED fusion. The recent Viewfactor experiments at NIF have shed light on both the observed capsule drive deficit and errors in the detailed modelling of hohlraums. The latter could be important factors in the inability to achieve the needed symmetry and energy concentration. The paper then recounts earlier work in Fast Ignition and the uses of pulsed-power for HED and fusion applications. It concludes with a description of a method for improving pulsed-power driven hohlraums that could potentially provide a factor of 10 in energy at NTF-like drive conditions and reach the energy bound for indirect drive ICF.

  17. High current density cathode for electrorefining in molten electrolyte

    Science.gov (United States)

    Li, Shelly X.

    2010-06-29

    A high current density cathode for electrorefining in a molten electrolyte for the continuous production and collection of loose dendritic or powdery deposits. The high current density cathode eliminates the requirement for mechanical scraping and electrochemical stripping of the deposits from the cathode in an anode/cathode module. The high current density cathode comprises a perforated electrical insulated material coating such that the current density is up to 3 A/cm.sup.2.

  18. High Density Lipoprotein Metabolism in Man

    Science.gov (United States)

    Blum, Conrad B.; Levy, Robert I.; Eisenberg, Shlomo; Hall, Marshall; Goebel, Robert H.; Berman, Mones

    1977-01-01

    The turnover of 125I-high density lipoprotein (HDL) was examined in a total of 14 studies in eight normal volunteers in an attempt to determine the metabolic relationship between apolipoproteins A-I (apoA-I) and A-II (apoA-II) of HDL and to define further some of the determinants of HDL metabolism. All subjects were first studied under conditions of an isocaloric balanced diet (40% fat, 40% carbohydrate). Four were then studied with an 80% carbohydrate diet, and two were studied while receiving nicotinic acid (1 g three times daily) and ingesting the same isocaloric balanced diet. The decay of autologous 125I-HDL and the appearance of urinary radioactivity were followed for at least 2 wk in each study. ApoA-I and apoA-II were isolated by Sephadex G-200 chromatography from serial plasma samples in each study. The specific activities of these peptides were then measured directly. It was found that the decay of specific activity of apoA-I and apoA-II were parallel to one another in all studies. The mean half-life of the terminal portion of decay was 5.8 days during the studies with a balanced diet. Mathematical modeling of the decay of plasma radioactivity and appearance of urinary radioactivity was most consistent with a two-compartment model. One compartment is within the plasma and exchanges with a nonplasma component. Catabolism occurs from both of these compartments. With a balanced isocaloric diet, the mean synthetic rate for HDL protein was 8.51 mg/kg per day. HDL synthesis was not altered by the high carbohydrate diet and was only slightly decreased by nicotinic acid treatment. These perturbations had effects on HDL catabolic pathways that were reciprocal in many respects. With an 80% carbohydrate diet, the rate of catabolism from the plasma compartment rose by a mean of 39.1%; with nicotinic acid treatment, it fell by 42.2%. Changes in the rate of catabolism from the second compartment were generally opposite those in the rate of catabolism from the plasma

  19. Variable kernel density estimation in high-dimensional feature spaces

    CSIR Research Space (South Africa)

    Van der Walt, Christiaan M

    2017-02-01

    Full Text Available Estimating the joint probability density function of a dataset is a central task in many machine learning applications. In this work we address the fundamental problem of kernel bandwidth estimation for variable kernel density estimation in high...

  20. Observable to explore high density behaviour of symmetry energy

    CERN Document Server

    Sood, Aman D

    2011-01-01

    We aim to see the sensitivity of collective transverse in-plane flow to symmetry energy at low as well as high densities and also to see the effect of different density dependencies of symmetry energy on the same.

  1. Synchrotron radiation absorber for high density loads

    Science.gov (United States)

    Anashin, V. V.; Kuzminych, V. S.; Trakhtenberg, E. M.; Zholents, A. A.

    1991-10-01

    A design of a special synchrotron radiation absorber for the storage ring VEPP-4M is presented. The density of the synchrotron radiation power on the absorber surface is up to 500 W/mm 2. The absorber is made from a beryllium plate, brazed inside to the copper vacuum chamber, which is intensively water-cooled from outside.

  2. High density and high temperature plasmas in Large Helical Device

    Science.gov (United States)

    Komori, Akio

    2010-11-01

    Recently a new confinement regime called Super Dense Core (SDC) mode was discovered in Large Helical Device (LHD). An extremely high density core region with more than ~ 1 × 1021 m-3 is obtained with the formation of an Internal Diffusion Barrier (IDB). The density gradient at the IDB is very high and the particle confinement in the core region is ~ 0.2 s. It is expected, for the future reactor, that the IDB-SDC mode has a possibility to achieve the self-ignition condition with lower temperature than expected before. Conventional approaches to increase the temperature have also been tried in LHD. For the ion heating, the perpendicular neutral beam injection effectively increased the ion temperature up to 5.6 keV with the formation of the internal transport barrier (ITB). In the electron heating experiments with 77 GHz gyrotrons, the highest electron temperature more than 15 keV was achieved, where plasmas are in the neoclassical regime.

  3. High density and high temperature plasmas in Large Helical Device

    Energy Technology Data Exchange (ETDEWEB)

    Komori, Akio, E-mail: komori@LHD.nifs.ac.jp [National Institute for Fusion Science, 322-6 Oroshi, Toki, Gifu 509-5292 (Japan)

    2010-11-01

    Recently a new confinement regime called Super Dense Core (SDC) mode was discovered in Large Helical Device (LHD). An extremely high density core region with more than {approx} 1 x 10{sup 21} m{sup -3} is obtained with the formation of an Internal Diffusion Barrier (IDB). The density gradient at the IDB is very high and the particle confinement in the core region is {approx} 0.2 s. It is expected, for the future reactor, that the IDB-SDC mode has a possibility to achieve the self-ignition condition with lower temperature than expected before. Conventional approaches to increase the temperature have also been tried in LHD. For the ion heating, the perpendicular neutral beam injection effectively increased the ion temperature up to 5.6 keV with the formation of the internal transport barrier (ITB). In the electron heating experiments with 77 GHz gyrotrons, the highest electron temperature more than 15 keV was achieved, where plasmas are in the neoclassical regime.

  4. Highly Compressed Ion Beams for High Energy Density Science

    CERN Document Server

    Friedman, Alex; Briggs, Richard J; Callahan, Debra; Caporaso, George; Celata, C M; Davidson, Ronald C; Faltens, Andy; Grant-Logan, B; Grisham, Larry; Grote, D P; Henestroza, Enrique; Kaganovich, Igor D; Lee, Edward; Lee, Richard; Leitner, Matthaeus; Nelson, Scott D; Olson, Craig; Penn, Gregory; Reginato, Lou; Renk, Tim; Rose, David; Sessler, Andrew M; Staples, John W; Tabak, Max; Thoma, Carsten H; Waldron, William; Welch, Dale; Wurtele, Jonathan; Yu, Simon

    2005-01-01

    The Heavy Ion Fusion Virtual National Laboratory (HIF-VNL) is developing the intense ion beams needed to drive matter to the High Energy Density (HED) regimes required for Inertial Fusion Energy (IFE) and other applications. An interim goal is a facility for Warm Dense Matter (WDM) studies, wherein a target is heated volumetrically without being shocked, so that well-defined states of matter at 1 to 10 eV are generated within a diagnosable region. In the approach we are pursuing, low to medium mass ions with energies just above the Bragg peak are directed onto thin target "foils," which may in fact be foams or "steel wool" with mean densities 1% to 100% of solid. This approach complements that being pursued at GSI, wherein high-energy ion beams deposit a small fraction of their energy in a cylindrical target. We present the requirements for warm dense matter experiments, and describe suitable accelerator concepts, including novel broadband traveling wave pulse-line, drift-tube linac, RF, and single-gap approa...

  5. Development of high temperature superconductors having high critical current density

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Gye Wong; Kim, C. J.; Lee, H.G.; Kwon, S. C.; Lee, H. J.; Kim, K. B.; Park, J. Y.; Jung, C. H

    2000-08-01

    Fabrication of high T{sub c} superconductors and its applications for electric power device were carried out for developing superconductor application technologies. High quality YBCO superconductors was fabricated by melt texture growth, top-seeded melt growth process and multi-seeded melt growth process and the properties was compared. The critical current density of the melt processed YBCO superconductors was about few 10,000 A/cm{sup 2} and the levitation force was 50 N. The processing time needed for the growth of the 123 single grain was greatly reduced by applying multi-seeding without no significant degradation of the levitation force. The multi-seeded melt growth process was confirmed as a time-saving and cost-effective method for the fabrication of bulk superconductors with controlled crystallographic orientation.

  6. Sputtered thin films for high density tape recording

    NARCIS (Netherlands)

    Nguyen, L.T.

    This thesis describes the investigation of sputtered thin film media for high density tape recording. As discussed in Chapter 1, to meet the tremendous demand of data storage, the density of recording tape has to be increased continuously. For further increasing the bit density the key factors are:

  7. Sputtered thin films for high density tape recording

    NARCIS (Netherlands)

    Nguyen, L.T.

    2004-01-01

    This thesis describes the investigation of sputtered thin film media for high density tape recording. As discussed in Chapter 1, to meet the tremendous demand of data storage, the density of recording tape has to be increased continuously. For further increasing the bit density the key factors are:

  8. High power densities from high-temperature material interactions

    Energy Technology Data Exchange (ETDEWEB)

    Morris, J.F.

    1981-01-01

    Thermionic energy conversion (TEC) and metallic-fluid heat pipes (MFHPs) offer important and unique advantages in terrestrial and space energy processing. And they are well suited to serve together synergistically. TEC and MFHPs operate through working-fluid vaporization, condensation cycles that accept great thermal power densities at high temperatures. TEC and MFHPs have apparently simple, isolated performance mechanisms that are somewhat similar. And they also have obviously difficult, complected material problems that again are somewhat similar. Intensive investigation reveals that aspects of their operating cycles and material problems tend to merge: high-temperature material effects determine the level and lifetime of performance. Simplified equations verify the preceding statement for TEC and MFHPs. Material properties and interactions exert primary influences on operational effectiveness. And thermophysicochemical stabilities dictate operating temperatures which regulate the thermoemissive currents of TEC and the vaporization flow rates of MFHPs. Major high-temperature material problems of TEC and MFHPs have been solved. These solutions lead to productive, cost-effective applications of current TEC and MFHPs - and point to significant improvements with anticipated technological gains.

  9. High density semiconductor nanodots by direct laser fabrication

    Science.gov (United States)

    Haghizadeh, Anahita; Yang, Haeyeon

    2016-03-01

    We report a direct method of fabricating high density nanodots on the GaAs(001) surfaces using laser irradiations on the surface. Surface images indicate that the large clumps are not accompanied with the formation of nanodots even though its density is higher than the critical density above which detrimental large clumps begin to show up in the conventional Stranski-Krastanov growth technique. Atomic force microscopy is used to image the GaAs(001) surfaces that are irradiated by high power laser pulses interferentially. The analysis suggests that high density quantum dots be fabricated directly on semiconductor surfaces.

  10. Heat transfer in high density electronics packaging

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    In order to get an insight into the thermal characteristic and to evaluate the thermal reliability of the "System in Packaging"(SIP), a new solution of electronics packaging, a heat transfer model of SIP was developed to predict the heat dissipation capacity and to investigate the effect of different factors on the temperature distribution in the electronics. The affecting parameters under consideration include the thermophysical properties of the substrates, the coefficient of convection heat transfer, the thickness of the chip, and the density of power dissipation. ALGOR, a kind of finite element analysis software,was used to do the model simulation. Based on the sinulation and analysis of the heat conduction and convection resistance, criteria for the thermal design were established and possible measurement for enhancing power dissipation was provided, The results show that the heat transfer model provides a new and effective way to the thermal design and thermal analysis of SIP and to the mechanical analysis for the further investigation of SIP.

  11. Sampling impairments influence over stealthy fiber-optic signal decryption

    Science.gov (United States)

    Yeminy, Tomer; Sadot, Dan; Zalevsky, Zeev

    2013-03-01

    Recently we have proposed a method for temporal and spectral stealthy fiber-optic communications. In this technique the signal is spread in the time domain below the noise level and the power spectral density of the signal is spread beneath the noise level in the frequency domain. The power spectral density of the signal is reconstructed by means of sampling which results in coherent addition of the encrypted signal spectral replicas. Hence, the sampling quality plays a major role in the ability to successfully decrypt the received covert signal. In this paper, we mathematically and numerically analyze the effect of sampling impairments over the decryption performance.

  12. Fiber-optic communication systems

    CERN Document Server

    Agrawal, Govind P

    2010-01-01

    This book provides a comprehensive account of fiber-optic communication systems. The 3rd edition of this book is used worldwide as a textbook in many universities. This 4th edition incorporates recent advances that have occurred, in particular two new chapters. One deals with the advanced modulation formats (such as DPSK, QPSK, and QAM) that are increasingly being used for improving spectral efficiency of WDM lightwave systems. The second chapter focuses on new techniques such as all-optical regeneration that are under development and likely to be used in future communication systems. All othe

  13. MAC Support for High Density Wireless Sensor Networks

    NARCIS (Netherlands)

    Taddia, C.; Meratnia, Nirvana; van Hoesel, L.F.W.; Mazzini, G.; Havinga, Paul J.M.

    Large scale and high density networks of tiny sensor nodes offer promising solutions for event detection and actuating applications. In this paper we address the effect of high density of wireless sensor network performance with a specific MAC protocol, the Lightweight Medium Access Control (LMAC).

  14. High-density carbon ablator ignition path with low-density gas-filled rugby hohlraum

    Science.gov (United States)

    Amendt, Peter; Ho, Darwin D.; Jones, Ogden S.

    2015-04-01

    A recent low gas-fill density (0.6 mg/cc 4He) cylindrical hohlraum experiment on the National Ignition Facility has shown high laser-coupling efficiency (>96%), reduced phenomenological laser drive corrections, and improved high-density carbon capsule implosion symmetry [Jones et al., Bull. Am. Phys. Soc. 59(15), 66 (2014)]. In this Letter, an ignition design using a large rugby-shaped hohlraum [Amendt et al., Phys. Plasmas 21, 112703 (2014)] for high energetics efficiency and symmetry control with the same low gas-fill density (0.6 mg/cc 4He) is developed as a potentially robust platform for demonstrating thermonuclear burn. The companion high-density carbon capsule for this hohlraum design is driven by an adiabat-shaped [Betti et al., Phys. Plasmas 9, 2277 (2002)] 4-shock drive profile for robust high gain (>10) 1-D ignition performance and large margin to 2-D perturbation growth.

  15. High-density carbon ablator ignition path with low-density gas-filled rugby hohlraum

    Energy Technology Data Exchange (ETDEWEB)

    Amendt, Peter; Ho, Darwin D.; Jones, Ogden S. [Lawrence Livermore National Laboratory, Livermore, California 94551 (United States)

    2015-04-15

    A recent low gas-fill density (0.6 mg/cc {sup 4}He) cylindrical hohlraum experiment on the National Ignition Facility has shown high laser-coupling efficiency (>96%), reduced phenomenological laser drive corrections, and improved high-density carbon capsule implosion symmetry [Jones et al., Bull. Am. Phys. Soc. 59(15), 66 (2014)]. In this Letter, an ignition design using a large rugby-shaped hohlraum [Amendt et al., Phys. Plasmas 21, 112703 (2014)] for high energetics efficiency and symmetry control with the same low gas-fill density (0.6 mg/cc {sup 4}He) is developed as a potentially robust platform for demonstrating thermonuclear burn. The companion high-density carbon capsule for this hohlraum design is driven by an adiabat-shaped [Betti et al., Phys. Plasmas 9, 2277 (2002)] 4-shock drive profile for robust high gain (>10) 1-D ignition performance and large margin to 2-D perturbation growth.

  16. Quantum Phenomena in High Energy Density Plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Murnane, Margaret [Univ. of Colorado, Boulder, CO (United States); Kapteyn, Henry [Univ. of Colorado, Boulder, CO (United States)

    2017-05-10

    The possibility of implementing efficient (phase matched) HHG upconversion of deep- UV lasers in multiply-ionized plasmas, with potentially unprecedented conversion efficiency is a fascinating prospect. HHG results from the extreme nonlinear response of matter to intense laser light:high harmonics are radiated as a result of a quantum coherent electron recollision process that occurs during laser field ionization of an atom. Under current support from this grant in work published in Science in 2015, we discovered a new regime of bright HHG in highly-ionized plasmas driven by intense UV lasers, that generates bright harmonics to photon energies >280eV

  17. Frequency-Shifted Interferometry — A Versatile Fiber-Optic Sensing Technique

    Directory of Open Access Journals (Sweden)

    Fei Ye

    2014-06-01

    Full Text Available Fiber-optic sensing is a field that is developing at a fast pace. Novel fiber-optic sensor designs and sensing principles constantly open doors for new opportunities. In this paper, we review a fiber-optic sensing technique developed in our research group called frequency-shifted interferometry (FSI. This technique uses a continuous-wave light source, an optical frequency shifter, and a slow detector. We discuss the operation principles of several FSI implementations and show their applications in fiber length and dispersion measurement, locating weak reflections along a fiber link, fiber-optic sensor multiplexing, and high-sensitivity cavity ring-down measurement. Detailed analysis of FSI system parameters is also presented.

  18. Application of a high density adsorbent in expanded bed adsorption ...

    African Journals Online (AJOL)

    PRECIOUS

    2010-01-11

    Jan 11, 2010 ... The high density of the adsorbent allowed the EBA to be operated at linear velocity as high as 657 cm/h ... through precipitation and even dialyzed before sample ... In EBA process, upward fluidized stationary phase with.

  19. Response of thermosphere density to high-latitude forcing

    Science.gov (United States)

    Yamazaki, Y.; Kosch, M. J.; Vickers, H.; Sutton, E. K.; Ogawa, Y.

    2014-12-01

    Solar wind-magnetospheric disturbances cause enhancements in the energy input to the high-latitude upper atmosphere through particle precipitation and Joule heating. As the upper atmosphere is heated and expanded during geomagnetically disturbed periods, the neutral density in the thermosphere increases at a fixed altitude. Conversely, the thermosphere contracts during the recovery phase of the disturbance, resulting in a decrease of the density. The main objectives of this study are (1) to determine the morphology of the global thermospheric density response to high-latitude forcing, and (2) to determine the recovery speed of the thermosphere density after geomagnetic disturbances. For (1), we use thermospheric density data measured by the Challenging Minisatellite Payload (CHAMP) satellite during 2000-2010. It is demonstrated that the density enhancement during disturbed periods occurs first in the dayside cusp region, and the density at other regions slowly follows it. The reverse process is observed when geomagnetic activity ceases; the density enhancement in the cusp region fades away first, then the global density slowly goes back to the quiet level. For (2), we analyze EISCAT Svalbard radar and Tromso UHF radar data to estimate thermospheric densities during the recovery phase of geomagnetic disturbances. We attempt to determine the time constant for the density recovery both inside and outside the cusp region.

  20. Nuclear Level Density at High Spin and Excitation Energy

    Institute of Scientific and Technical Information of China (English)

    A.N. Behkami; Z. Kargar

    2001-01-01

    The intensive studies of equilibrium processes in heavy-ion reaction have produced a need for information on nuclear level densities at high energies and spins. The Fermi gas level density is often used in investigation of heavy-ion reaction studies. Some papers have claimed that nuclear level densities might deviate substantially from the Fermi gas predications at excitations related to heavy-ion reactions. The formulae of calculation of the nuclear level density based on the theory of superconductivity are presented, special attention is paid to the dependence of the level density on the angular momentum. The spin-dependent nuclear level density is evaluated using the pairing interaction. The resulting level density for an average spin of 52h is evaluated for 155Er and compared with experimental data. Excellent agreement between experiment and theory is obtained.``

  1. Breast density estimation from high spectral and spatial resolution MRI.

    Science.gov (United States)

    Li, Hui; Weiss, William A; Medved, Milica; Abe, Hiroyuki; Newstead, Gillian M; Karczmar, Gregory S; Giger, Maryellen L

    2016-10-01

    A three-dimensional breast density estimation method is presented for high spectral and spatial resolution (HiSS) MR imaging. Twenty-two patients were recruited (under an Institutional Review Board--approved Health Insurance Portability and Accountability Act-compliant protocol) for high-risk breast cancer screening. Each patient received standard-of-care clinical digital x-ray mammograms and MR scans, as well as HiSS scans. The algorithm for breast density estimation includes breast mask generating, breast skin removal, and breast percentage density calculation. The inter- and intra-user variabilities of the HiSS-based density estimation were determined using correlation analysis and limits of agreement. Correlation analysis was also performed between the HiSS-based density estimation and radiologists' breast imaging-reporting and data system (BI-RADS) density ratings. A correlation coefficient of 0.91 ([Formula: see text]) was obtained between left and right breast density estimations. An interclass correlation coefficient of 0.99 ([Formula: see text]) indicated high reliability for the inter-user variability of the HiSS-based breast density estimations. A moderate correlation coefficient of 0.55 ([Formula: see text]) was observed between HiSS-based breast density estimations and radiologists' BI-RADS. In summary, an objective density estimation method using HiSS spectral data from breast MRI was developed. The high reproducibility with low inter- and low intra-user variabilities shown in this preliminary study suggest that such a HiSS-based density metric may be potentially beneficial in programs requiring breast density such as in breast cancer risk assessment and monitoring effects of therapy.

  2. Ultra high energy density and fast discharge nanocomposite capacitors

    Science.gov (United States)

    Tang, Haixiong; Sodano, Henry A.

    2013-04-01

    Nanocomposites containing high dielectric permittivity ceramics embedded in high breakdown strength polymers are currently of considerable interest as a solution for the development of high energy density capacitors. However, the improvement of dielectric permittivity comes at expense of the breakdown strength leading to limit the final energy density. Here, an ultra-high energy density nanocomposite was fabricated based on high aspect ratio barium strontium titanate nanowires. The pyroelectric phase Ba0.2Sr0.8TiO3 was chosen for the nanowires combined with quenched PVDF to fabricate high energy density nanocomposite. The energy density with 7.5% Ba0.2Sr0.8TiO3 nanowires reached 14.86 J/cc at 450 MV/m, which represented a 42.9% increase in comparison to the PVDF with an energy density of 10.4 J/cc at the same electric field. The capacitors have 1138% greater than higher energy density than commercial biaxial oriented polypropylene capacitors (1.2 J/cc at 640). These results demonstrate that the high aspect ratio nanowires can be used to produce nanocomposite capacitors with greater performance than the neat polymers thus providing a novel process for the development of future pulsed-power capacitors.

  3. Fiber-optic sensor applications in civil and geotechnical engineering

    Science.gov (United States)

    Habel, Wolfgang R.; Krebber, Katerina

    2011-09-01

    Different types of fiber-optic sensors based on glass or polymeric fibers are used to evaluate material behavior or to monitor the integrity and long-term stability of load-bearing structure components. Fiber-optic sensors have been established as a new and innovative measurement technology in very different fields, such as material science, civil engineering, light-weight structures, geotechnical areas as well as chemical and high-voltage substations. Very often, mechanical quantities such as deformation, strain or vibration are requested. However, measurement of chemical quantities in materials and structure components, such as pH value in steel reinforced concrete members also provides information about the integrity of concrete structures. A special fiber-optic chemical sensor for monitoring the alkaline state (pH value) of the cementitious matrix in steel-reinforced concrete structures with the purpose of early detection of corrosion-initiating factors is described. The paper presents the use of several fiber-optic sensor technologies in engineering. One example concerns the use of highly resolving concrete-embeddable fiber Fabry-Perot acoustic emission (AE) sensors for the assessment of the bearing behaviour of large concrete piles in existing foundations or during and after its installation. Another example concerns fiber Bragg grating (FBG) sensors attached to anchor steels (micro piles) to measure the strain distribution in loaded soil anchors. Polymer optical fibers (POF) can be — because of their high elasticity and high ultimate strain — well integrated into textiles to monitor their deformation behaviour. Such "intelligent" textiles are capable of monitoring displacement of soil or slopes, critical mechanical deformation in geotechnical structures (dikes, dams, and embankments) as well as in masonry structures during and after earthquakes.

  4. 128x128 Ultra-High Density Optical Interconnect Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Future NASA programs like Tertiary Planet Finder (TPF) require high-density deformable mirrors with up to 16,000 actuators to enable direct imaging of planets around...

  5. 128x128 Ultra-High Density Optical Interconnect Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Future NASA programs like Tertiary Planet Finder (TPF) require high density deformable mirrors with upto 16,000 actuators to enable direct imaging of planets around...

  6. High current density nanofilament cathodes for microwave amplifiers

    NARCIS (Netherlands)

    Schnell, J-P.; Minoux, E.; Gangloff, L.; Vincent, P.; Legagneux, P.; Dieumegard, D.; David, J.-F.; Peauger, F.; Hudanski, L.; Teo, K.B.K.; Lacerda, R.; Chhowalla, M.; Hasko, D.G.; Ahmed, H.; Amaratunga, G.A.J.; Milne, W.I.; Vila, L.; Dauginet-De Pra, L.; Demoustier-Champagne, S.; Ferain, E.; Legras, R.; Piraux, L.; Gröening, O.; Raedt, H. De; Michielsen, K.

    2004-01-01

    We study high current density nanofilament cathodes for microwave amplifiers. Two different types of aligned nanofilament array have been studied: first, metallic nanowires grown by electrodeposition into nanoporous templates at very low temperature (T

  7. High energy density nanocomposite capacitors using non-ferroelectric nanowires

    Science.gov (United States)

    Tang, Haixiong; Sodano, Henry A.

    2013-02-01

    A high energy density nanocomposite capacitor is fabricated by incorporating high aspect ratio functionalized TiO2 nanowires (NWs) into a polyvinylidene-fluoride matrix. These nanocomposites exhibited energy density as high as 12.4 J/cc at 450 MV/m, which is nine times larger than commercial biaxially oriented polypropylene polypropylene capacitors (1.2 J/cc at 640 MV/m). Also, the power density can reach 1.77 MW/cc with a discharge speed of 2.89 μs. The results presented here demonstrate that nanowires can be used to develop nanocomposite capacitors with high energy density and fast discharge speed for future pulsed-power applications.

  8. The usefulness of total cholesterol and high density lipoprotein ...

    African Journals Online (AJOL)

    The usefulness of total cholesterol and high density lipoprotein - cholesterol ratio in ... cholesterol and/or highdensity lipoprotein cholesterol/total cholesterol ratios in the interpretation of lipid profile result in clinical practice. ... Article Metrics.

  9. Spontaneous magnetization in high-density quark matter

    DEFF Research Database (Denmark)

    Tsue, Yasuhiko; da Providência, João; Providência, Constanca;

    2015-01-01

    It is shown that spontaneous magnetization occurs due to the anomalous magnetic moments of quarks in high-density quark matter under the tensor-type four-point interaction. The spin polarized condensate for each flavor of quark appears at high baryon density, which leads to the spontaneous...... magnetization due to the anomalous magnetic moments of quarks. The implications for the strong magnetic field in compact stars is discussed....

  10. Workshop on extremely high energy density plasmas and their diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Ishii, Shozo (ed.)

    2001-09-01

    Compiled are the papers presented at the workshop on 'Extremely High Energy Density Plasmas and Their Diagnostics' held at National Institute for Fusion Science. The papers cover physics and applications of extremely high-energy density plasmas such as dense z-pinch, plasma focus, and intense pulsed charged beams. Separate abstracts were presented for 7 of the papers in this report. The remaining 25 were considered outside the subject scope of INIS. (author)

  11. Fifth International Conference on High Energy Density Physics

    Energy Technology Data Exchange (ETDEWEB)

    Beg, Farhat

    2017-07-05

    The Fifth International Conference on High Energy Density Physics (ICHED 2015) was held in the Catamaran Hotel in San Diego from August 23-27, 2015. This meeting was the fifth in a series which began in 2008 in conjunction with the April meeting of the American Physical Society (APS). The main goal of this conference has been to bring together researchers from all fields of High Energy Density Science (HEDS) into one, unified meeting.

  12. Fabrication of very high density fuel pellets of thorium dioxide

    Science.gov (United States)

    Shiratori, Tetsuo; Fukuda, Kosaku

    1993-06-01

    Very high density ThO 2 pellets were prepared without binders and lubricants from the ThO 2 powder originated by the thorium oxalate, which was aimed to simplify the fabrication process by skipping a preheat treatment. The as-received ThO 2 powder with a surface area of 4.56 m 2/g was ball-milled up to about 9 m 2/g in order to increase the green pellet density as high as possible. Both of the single-sided and the double-sided pressing were tested in the range from 2 to 5 t/cm 2 in the green pellet formation. Sintering temperature was such low as 1550°C. The pellet prepared in this experiment had a very high density in the range from about 96 to 98% TD without any cracks, in which a difference of the pellet density was not recognized in the single-sided pressing methods.

  13. High-density scintillating glasses for a proton imaging detector

    Science.gov (United States)

    Tillman, I. J.; Dettmann, M. A.; Herrig, V.; Thune, Z. L.; Zieser, A. J.; Michalek, S. F.; Been, M. O.; Martinez-Szewczyk, M. M.; Koster, H. J.; Wilkinson, C. J.; Kielty, M. W.; Jacobsohn, L. G.; Akgun, U.

    2017-06-01

    High-density scintillating glasses are proposed for a novel proton-imaging device that can improve the accuracy of the hadron therapy. High-density scintillating glasses are needed to build a cost effective, compact calorimeter that can be attached to a gantry. This report summarizes the study on Europium, Terbium, and Cerium-doped scintillating glasses that were developed containing heavy elements such as Lanthanum, Gadolinium, and Tungsten. The density of the samples reach up to 5.9 g/cm3, and their 300-600 nm emission overlaps perfectly with the peak cathode sensitivity of the commercial photo detectors. The developed glasses do not require any special quenching and can be poured easily, which makes them a good candidate for production in various geometries. Here, the glass making conditions, preliminary tests on optical and physical properties of these scintillating, high-density, oxide glasses developed for a novel medical imaging application are reported.

  14. Stability of high cell density brewery fermentations during serial repitching.

    Science.gov (United States)

    Verbelen, Pieter J; Dekoninck, Tinne M L; Van Mulders, Sebastiaan E; Saerens, Sofie M G; Delvaux, Filip; Delvaux, Freddy R

    2009-11-01

    The volumetric productivity of the beer fermentation process can be increased by using a higher pitching rate (i.e. higher inoculum size). However, the decreased yeast net growth observed in these high cell density brewery fermentations can adversely affect the physiological stability throughout subsequent yeast generations. Therefore, different O(2) conditions (wort aeration and yeast preoxygenation) were applied to high cell density fermentation and eight generations of fermentations were evaluated together with conventional fermentations. Freshly propagated high cell density populations adapted faster to the fermentative conditions than normal cell density populations. Preoxygenating the yeast was essential for the yeast physiological and beer flavor compound stability of high cell density fermentations during serial repitching. In contrast, the use of non-preoxygenated yeast resulted in inadequate growth which caused (1) insufficient yield of biomass to repitch all eight generations, (2) a 10% decrease in viability, (3) a moderate increase of yeast age, (4) and a dramatic increase of the unwanted flavor compounds acetaldehyde and total diacetyl during the sequence of fermentations. Therefore, to achieve sustainable high cell density fermentations throughout the economical valuable process of serial repitching, adequate yeast growth is essential.

  15. Beyond high-density lipoprotein cholesterol levels evaluating high-density lipoprotein function as influenced by novel therapeutic approaches

    National Research Council Canada - National Science Library

    deGoma, Emil M; deGoma, Rolando L; Rader, Daniel J

    2008-01-01

    A number of therapeutic strategies targeting high-density lipoprotein (HDL) cholesterol and reverse cholesterol transport are being developed to halt the progression of atherosclerosis or even induce regression...

  16. Comparison of low density and high density pedicle screw instrumentation in Lenke 1 adolescent idiopathic scoliosis.

    Science.gov (United States)

    Shen, Mingkui; Jiang, Honghui; Luo, Ming; Wang, Wengang; Li, Ning; Wang, Lulu; Xia, Lei

    2017-08-02

    The correlation between implant density and deformity correction has not yet led to a precise conclusion in adolescent idiopathic scoliosis (AIS). The aim of this study was to evaluate the effects of low density (LD) and high density (HD) pedicle screw instrumentation in terms of the clinical, radiological and Scoliosis Research Society (SRS)-22 outcomes in Lenke 1 AIS. We retrospectively reviewed 62 consecutive Lenke 1 AIS patients who underwent posterior spinal arthrodesis using all-pedicle screw instrumentation with a minimum follow-up of 24 months. The implant density was defined as the number of screws per spinal level fused. Patients were then divided into two groups according to the average implant density for the entire study. The LD group (n = 28) had fewer than 1.61 screws per level, while the HD group (n = 34) had more than 1.61 screws per level. The radiographs were analysed preoperatively, postoperatively and at final follow-up. The perioperative and SRS-22 outcomes were also assessed. Independent sample t tests were used between the two groups. Comparisons between the two groups showed no significant differences in the correction of the main thoracic curve and thoracic kyphosis, blood transfusion, hospital stay, and SRS-22 scores. Compared with the HD group, there was a decreased operating time (278.4 vs. 331.0 min, p = 0.004) and decreased blood loss (823.6 vs. 1010.9 ml, p = 0.048), pedicle screws needed (15.1 vs. 19.6, p density and high density pedicle screw instrumentation achieved satisfactory deformity correction in Lenke 1 AIS patients. However, the operating time and blood loss were reduced, and the implant costs were decreased with the use of low screw density constructs.

  17. High dislocation density of tin induced by electric current

    Energy Technology Data Exchange (ETDEWEB)

    Liao, Yi-Han; Liang, Chien-Lung; Lin, Kwang-Lung, E-mail: matkllin@mail.ncku.edu.tw [Department of Material Science and Engineering, National Cheng Kung University, Tainan 70101, Taiwan, R. O. C (China); Wu, Albert T. [Department of Chemical and Material Engineering, National Central University, Jhongli 32001, Taiwan, R. O. C (China)

    2015-12-15

    A dislocation density of as high as 10{sup 17} /m{sup 2} in a tin strip, as revealed by high resolution transmission electron microscope, was induced by current stressing at 6.5 x 10{sup 3} A/ cm{sup 2}. The dislocations exist in terms of dislocation line, dislocation loop, and dislocation aggregates. Electron Backscattered Diffraction images reflect that the high dislocation density induced the formation of low deflection angle subgrains, high deflection angle Widmanstätten grains, and recrystallization. The recrystallization gave rise to grain refining.

  18. Fiber-Optic Micrometeoroid/Orbital Debris Impact Detector System

    Science.gov (United States)

    Christiansen, Eric L.; Tennyson, R. C.; Morison, W. D.

    2012-01-01

    A document describes a reliable, lightweight micrometeoroid/orbital debris (MMOD) detection system that can be located at strategic positions of "high consequence" to provide real-time warning of a penetration, its location, and the extent of the damage to a spacecraft. The concept is to employ fiber-optic sensors to detect impact damage and penetration of spacecraft structures. The fibers are non-electrical, employ light waves, and are immune to electromagnetic interference. The fiber-optic sensor array can be made as a stand-alone product, being bonded to a flexible membrane material or a structure that is employed as a MMOD shield material. The optical sensors can also be woven into hybrid MMOD shielding fabrics. The glass fibers of the fiber-optic sensor provide a dual purpose in contributing to the breakup of MMOD projectiles. The grid arrays can be made in a modular configuration to provide coverage over any area desired. Each module can be connected to a central scanner instrument and be interrogated in a continuous or periodic mode.

  19. Noise reduction in muon tomography for detecting high density objects

    CERN Document Server

    Benettoni, M; Bonomi, G; Calvagno, G; Calvini, P; Checchia, P; Cortelazzo, G; Cossutta, L; Donzella, A; Furlan, M; Gonella, F; Pegoraro, M; Garola, A Rigoni; Ronchese, P; Squarcia, S; Subieta, M; Vanini, S; Viesti, G; Zanuttigh, P; Zenoni, A; Zumerle, G

    2013-01-01

    The muon tomography technique, based on multiple Coulomb scattering of cosmic ray muons, has been proposed as a tool to detect the presence of high density objects inside closed volumes. A new and innovative method is presented in this paper to handle the density fluctuations (noise) of reconstructed images, that are a known problem of this technique. The effectiveness of our method is evaluated using experimental data obtained with a muon tomography prototype located at Legnaro National Laboratories (LNL) of the Istituto Nazionale di Fisica Nucleare (INFN). The results reported in this paper, obtained with real cosmic ray data, show that with appropriate image filtering and muon momentum classification, the muon tomography technique can detect in short times high density materials, such as lead, when surrounded by light or medium density material. A comparison with algorithms published in literature is also presented.

  20. Noise reduction in muon tomography for detecting high density objects

    Science.gov (United States)

    Benettoni, M.; Bettella, G.; Bonomi, G.; Calvagno, G.; Calvini, P.; Checchia, P.; Cortelazzo, G.; Cossutta, L.; Donzella, A.; Furlan, M.; Gonella, F.; Pegoraro, M.; Rigoni Garola, A.; Ronchese, P.; Squarcia, S.; Subieta, M.; Vanini, S.; Viesti, G.; Zanuttigh, P.; Zenoni, A.; Zumerle, G.

    2013-12-01

    The muon tomography technique, based on multiple Coulomb scattering of cosmic ray muons, has been proposed as a tool to detect the presence of high density objects inside closed volumes. In this paper a new and innovative method is presented to handle the density fluctuations (noise) of reconstructed images, a well known problem of this technique. The effectiveness of our method is evaluated using experimental data obtained with a muon tomography prototype located at the Legnaro National Laboratories (LNL) of the Istituto Nazionale di Fisica Nucleare (INFN). The results reported in this paper, obtained with real cosmic ray data, show that with appropriate image filtering and muon momentum classification, the muon tomography technique can detect high density materials, such as lead, albeit surrounded by light or medium density material, in short times. A comparison with algorithms published in literature is also presented.

  1. High energy density interpenetrating networks from ionic networks and silicone

    DEFF Research Database (Denmark)

    Yu, Liyun; Madsen, Frederikke Bahrt; Hvilsted, Søren

    2015-01-01

    The energy density of dielectric elastomers (DEs) is sought increased for better exploitation of the DE technology since an increased energy density means that the driving voltage for a certain strain can be lowered in actuation mode or alternatively that more energy can be harvested in generator...... mode. One way to increase the energy density is to increase dielectric permittivity of the elastomer. A novel silicone elastomer system with high dielectric permittivity was prepared through the development of interpenetrating networks from ionically assembled silicone polymers and covalently...

  2. Solid Oxide Electrolysis Cells: Degradation at High Current Densities

    DEFF Research Database (Denmark)

    Knibbe, Ruth; Traulsen, Marie Lund; Hauch, Anne;

    2010-01-01

    The degradation of Ni/yttria-stabilized zirconia (YSZ)-based solid oxide electrolysis cells operated at high current densities was studied. The degradation was examined at 850°C, at current densities of −1.0, −1.5, and −2.0 A/cm2, with a 50:50 (H2O:H2) gas supplied to the Ni/YSZ hydrogen electrode...

  3. BCS Theory of Hadronic Matter at High Densities

    DEFF Research Database (Denmark)

    Bohr, Henrik; Panda, Prafulla K.; Providencia, Constanca

    2012-01-01

    The equilibrium between the so-called 2SC and CFL phases of strange quark matter at high densities is investigated in the framework of a simple schematic model of the NJL type. Equal densities are assumed for quarks u, d and s. The 2SC phase is here described by a color-flavor symmetric state...... than is usual in NJL type models. This should be adequate if the relevant chemical potential does not exceed 0.6 GeV....

  4. Development of plasma bolometers using fiber-optic temperature sensors

    Science.gov (United States)

    Reinke, M. L.; Han, M.; Liu, G.; van Eden, G. G.; Evenblij, R.; Haverdings, M.; Stratton, B. C.

    2016-11-01

    Measurements of radiated power in magnetically confined plasmas are important for exhaust studies in present experiments and expected to be a critical diagnostic for future fusion reactors. Resistive bolometer sensors have long been utilized in tokamaks and helical devices but suffer from electromagnetic interference (EMI). Results are shown from initial testing of a new bolometer concept based on fiber-optic temperature sensor technology. A small, 80 μm diameter, 200 μm long silicon pillar attached to the end of a single mode fiber-optic cable acts as a Fabry-Pérot cavity when broadband light, λo ˜ 1550 nm, is transmitted along the fiber. Changes in temperature alter the optical path length of the cavity primarily through the thermo-optic effect, resulting in a shift of fringes reflected from the pillar detected using an I-MON 512 OEM spectrometer. While initially designed for use in liquids, this sensor has ideal properties for use as a plasma bolometer: a time constant, in air, of ˜150 ms, strong absorption in the spectral range of plasma emission, immunity to local EMI, and the ability to measure changes in temperature remotely. Its compact design offers unique opportunities for integration into the vacuum environment in places unsuitable for a resistive bolometer. Using a variable focus 5 mW, 405 nm, modulating laser, the signal to noise ratio versus power density of various bolometer technologies are directly compared, estimating the noise equivalent power density (NEPD). Present tests show the fiber-optic bolometer to have NEPD of 5-10 W/m2 when compared to those of the resistive bolometer which can achieve coatings, along with improving the spectral resolution of the interrogator.

  5. Mendelian Disorders of High-Density Lipoprotein Metabolism

    NARCIS (Netherlands)

    Oldoni, Federico; Sinke, Richard J.; Kuivenhoven, Jan Albert

    2014-01-01

    High-density lipoproteins (HDLs) are a highly heterogeneous and dynamic group of the smallest and densest lipoproteins present in the circulation. This review provides the current molecular insight into HDL metabolism led by articles describing mutations in genes that have a large affect on HDL chol

  6. Quark matter at high density based on an extended confined isospin-density-dependent mass model

    Science.gov (United States)

    Qauli, A. I.; Sulaksono, A.

    2016-01-01

    We investigate the effect of the inclusion of relativistic Coulomb terms in a confined-isospin-density-dependent-mass (CIDDM) model of strange quark matter (SQM). We found that if we include the Coulomb term in scalar density form, the SQM equation of state (EOS) at high densities is stiffer but if we include the Coulomb term in vector density form it is softer than that of the standard CIDDM model. We also investigate systematically the role of each term of the extended CIDDM model. Compared with what was reported by Chu and Chen [Astrophys. J. 780, 135 (2014)], we found the stiffness of SQM EOS is controlled by the interplay among the oscillator harmonic, isospin asymmetry and Coulomb contributions depending on the parameter's range of these terms. We have found that the absolute stable condition of SQM and the mass of 2 M⊙ pulsars can constrain the parameter of oscillator harmonic κ1≈0.53 in the case the Coulomb term is excluded. If the Coulomb term is included, for the models with their parameters are consistent with SQM absolute stability condition, the 2.0 M⊙ constraint more prefers the maximum mass prediction of the model with the scalar Coulomb term than that of the model with the vector Coulomb term. On the contrary, the high densities EOS predicted by the model with the vector Coulomb is more compatible with the recent perturbative quantum chromodynamics result [1] than that predicted by the model with the scalar Coulomb. Furthermore, we also observed the quark composition in a very high density region depends quite sensitively on the kind of Coulomb term used.

  7. High-density turbidity currents: Are they sandy debris flows?

    Energy Technology Data Exchange (ETDEWEB)

    Shanmugam, G. [Mobil Exploration and Producing Technical Center, Dallas, TX (United States)

    1996-01-01

    Conventionally, turbidity currents are considered as fluidal flows in which sediment is supported by fluid turbulence, whereas debris flows are plastic flows in which sediment is supported by matrix strength, dispersive pressure, and buoyant lift. The concept of high-density turbidity current refers to high-concentration, commonly non-turbulent, flows of fluids in which sediment is supported mainly by matrix strength, dispersive pressure, and buoyant lift. The conventional wisdom that traction carpets with entrained turbulent clouds on top represent high-density turbidity currents is a misnomer because traction carpets are neither fluidal nor turbulent. Debris flows may also have entrained turbulent clouds on top. The traction carpet/debris flow and the overriding turbulent clouds are two separate entities in terms of flow rheology and sediment-support mechanism. In experimental and theoretical studies, which has linked massive sands and floating clasts to high-density turbidity currents, the term high-density turbidity current has actually been used for laminar flows. In alleviating this conceptual problem, sandy debris flow is suggested as a substitute for high-density turbidity current. Sandy debris flows represent a continuous spectrum of processes between cohesive and cohesionless debris flows. Commonly they are rheologically plastic. They may occur with or without entrained turbulent clouds on top. Their sediment-support mechanisms include matrix strength, dispersive pressure, and buoyant lift. They are characterized by laminar flow conditions, a moderate to high grain concentration, and a low to moderate mud content. Although flows evolve and transform during the course of transport in density-stratified flows, the preserved features in a deposit are useful to decipher only the final stages of deposition. At present, there are no established criteria to decipher transport mechanism from the depositional record.

  8. High density data storage principle, technology, and materials

    CERN Document Server

    Zhu, Daoben

    2009-01-01

    The explosive increase in information and the miniaturization of electronic devices demand new recording technologies and materials that combine high density, fast response, long retention time and rewriting capability. As predicted, the current silicon-based computer circuits are reaching their physical limits. Further miniaturization of the electronic components and increase in data storage density are vital for the next generation of IT equipment such as ultra high-speed mobile computing, communication devices and sophisticated sensors. This original book presents a comprehensive introduction to the significant research achievements on high-density data storage from the aspects of recording mechanisms, materials and fabrication technologies, which are promising for overcoming the physical limits of current data storage systems. The book serves as an useful guide for the development of optimized materials, technologies and device structures for future information storage, and will lead readers to the fascin...

  9. Using high-resolution fiber-optic distributed temperature sensing to measure spatially resolved speed and temperature of airflows in a shallow gully

    Science.gov (United States)

    Thomas, Christoph; Sayde, Chadi; Selker, John

    2015-04-01

    We present a novel observational technique that was applied to study transient shallow cold-air drainages and pools in undulating terrain in weak-wind conditions. Wind speed and air temperature at thousands of closely co-located locations were measured simultaneously at high spatial (0.25m) and temporal (5s) resolution using paired passive and actively heated optical fibers with a distributed temperature sensing system (DTS). The fibers were deployed in a transect across a shallow gully with a total length of 230 m at three levels (0.5, 1, and 2m above ground level) during the Shallow Cold Pool (SCP) Experiment in Northern Colorado, USA in October and November 2012. While we previously demonstrated that air temperature and the thermal structure of the near-surface turbulence can be observed with the DTS technique (Thomas et al., 2012, Zeeman et al., 2014), the novelty here consists of additionally measuring wind speed on horizontal scales of several hundreds of meters with fine resolution. Analogous to a hot-wire anemometer, the approach is based on the principal of velocity-dependent heat transfer from a heated surface. We present the theoretical basis for the DTS wind and temperature measurements and validate it against point observations from sonic anemometers and thermo-hygrometers. A space-time analysis of the near-surface gully flow and temperature field is presented based upon the observations subject to an orthogonal multi-resolution decomposition for selected cases. The temporal variability of near-surface air temperature was largest half-way up the slope caused be shifts of the very sharp thermal boundary between the density driven cold-air drainage flow in the gully bottom and the lower density air on the slopes, which was significantly warmed by enhanced downward mixing of sensible heat in the lee of the gully shoulder. Stationary horizontal temperature gradients at this thermal boundary amounted to 6 to 8 K m-1 and persisted for several hours unless

  10. Smart-phone based computational microscopy using multi-frame contact imaging on a fiber-optic array.

    Science.gov (United States)

    Navruz, Isa; Coskun, Ahmet F; Wong, Justin; Mohammad, Saqib; Tseng, Derek; Nagi, Richie; Phillips, Stephen; Ozcan, Aydogan

    2013-10-21

    We demonstrate a cellphone based contact microscopy platform, termed Contact Scope, which can image highly dense or connected samples in transmission mode. Weighing approximately 76 grams, this portable and compact microscope is installed on the existing camera unit of a cellphone using an opto-mechanical add-on, where planar samples of interest are placed in contact with the top facet of a tapered fiber-optic array. This glass-based tapered fiber array has ~9 fold higher density of fiber optic cables on its top facet compared to the bottom one and is illuminated by an incoherent light source, e.g., a simple light-emitting-diode (LED). The transmitted light pattern through the object is then sampled by this array of fiber optic cables, delivering a transmission image of the sample onto the other side of the taper, with ~3× magnification in each direction. This magnified image of the object, located at the bottom facet of the fiber array, is then projected onto the CMOS image sensor of the cellphone using two lenses. While keeping the sample and the cellphone camera at a fixed position, the fiber-optic array is then manually rotated with discrete angular increments of e.g., 1-2 degrees. At each angular position of the fiber-optic array, contact images are captured using the cellphone camera, creating a sequence of transmission images for the same sample. These multi-frame images are digitally fused together based on a shift-and-add algorithm through a custom-developed Android application running on the smart-phone, providing the final microscopic image of the sample, visualized through the screen of the phone. This final computation step improves the resolution and also removes spatial artefacts that arise due to non-uniform sampling of the transmission intensity at the fiber optic array surface. We validated the performance of this cellphone based Contact Scope by imaging resolution test charts and blood smears.

  11. Frontiers for Discovery in High Energy Density Physics

    Energy Technology Data Exchange (ETDEWEB)

    Davidson, R. C.; Katsouleas, T.; Arons, J.; Baring, M.; Deeney, C.; Di Mauro, L.; Ditmire, T.; Falcone, R.; Hammer, D.; Hill, W.; Jacak, B.; Joshi, C.; Lamb, F.; Lee, R.; Logan, B. G.; Melissinos, A.; Meyerhofer, D.; Mori, W.; Murnane, M.; Remington, B.; Rosner, R.; Schneider, D.; Silvera, I.; Stone, J.; Wilde, B.; Zajc. W.

    2004-07-20

    The report is intended to identify the compelling research opportunities of high intellectual value in high energy density physics. The opportunities for discovery include the broad scope of this highly interdisciplinary field that spans a wide range of physics areas including plasma physics, laser and particle beam physics, nuclear physics, astrophysics, atomic and molecular physics, materials science and condensed matter physics, intense radiation-matter interaction physics, fluid dynamics, and magnetohydrodynamics

  12. Development of plasma bolometers using fiber-optic temperature sensors

    Energy Technology Data Exchange (ETDEWEB)

    Reinke, M. L., E-mail: reinkeml@ornl.gov [Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831 (United States); Han, M.; Liu, G. [University of Nebraska-Lincoln, Lincoln, Nebraska 68588 (United States); Eden, G. G. van [Dutch Institute for Fundamental Energy Research, De Zaale 20, 5612 AJ Eindhoven (Netherlands); Evenblij, R.; Haverdings, M. [Technobis, Pyrietstraat 2, 1812 SC Alkmaar (Netherlands); Stratton, B. C. [Princeton Plasma Physics Laboratory, P.O. Box 451, Princeton, New Jersey 08543 (United States)

    2016-11-15

    Measurements of radiated power in magnetically confined plasmas are important for exhaust studies in present experiments and expected to be a critical diagnostic for future fusion reactors. Resistive bolometer sensors have long been utilized in tokamaks and helical devices but suffer from electromagnetic interference (EMI). Results are shown from initial testing of a new bolometer concept based on fiber-optic temperature sensor technology. A small, 80 μm diameter, 200 μm long silicon pillar attached to the end of a single mode fiber-optic cable acts as a Fabry–Pérot cavity when broadband light, λ{sub o} ∼ 1550 nm, is transmitted along the fiber. Changes in temperature alter the optical path length of the cavity primarily through the thermo-optic effect, resulting in a shift of fringes reflected from the pillar detected using an I-MON 512 OEM spectrometer. While initially designed for use in liquids, this sensor has ideal properties for use as a plasma bolometer: a time constant, in air, of ∼150 ms, strong absorption in the spectral range of plasma emission, immunity to local EMI, and the ability to measure changes in temperature remotely. Its compact design offers unique opportunities for integration into the vacuum environment in places unsuitable for a resistive bolometer. Using a variable focus 5 mW, 405 nm, modulating laser, the signal to noise ratio versus power density of various bolometer technologies are directly compared, estimating the noise equivalent power density (NEPD). Present tests show the fiber-optic bolometer to have NEPD of 5-10 W/m{sup 2} when compared to those of the resistive bolometer which can achieve <0.5 W/m{sup 2} in the laboratory, but this can degrade to 1-2 W/m{sup 2} or worse when installed on a tokamak. Concepts are discussed to improve the signal to noise ratio of this new fiber-optic bolometer by reducing the pillar height and adding thin metallic coatings, along with improving the spectral resolution of the interrogator.

  13. Study of Volumetrically Heated Ultra-High Energy Density Plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Rocca, Jorge J. [Colorado State Univ., Fort Collins, CO (United States)

    2016-10-27

    Heating dense matter to millions of degrees is important for applications, but requires complex and expensive methods. The major goal of the project was to demonstrate using a compact laser the creation of a new ultra-high energy density plasma regime characterized by simultaneous extremely high temperature and high density, and to study it combining experimental measurements and advanced simulations. We have demonstrated that trapping of intense femtosecond laser pulses deep within ordered nanowire arrays can heat near solid density matter into a new ultra hot plasma regime. Extreme electron densities, and temperatures of several tens of million degrees were achieved using laser pulses of only 0.5 J energy from a compact laser. Our x-ray spectra and simulations showed that extremely highly ionized plasma volumes several micrometers in depth are generated by irradiation of gold and Nickel nanowire arrays with femtosecond laser pulses of relativistic intensities. We obtained extraordinarily high degrees of ionization (e.g. we peeled 52 electrons from gold atoms, and up to 26 electrons from nickel atoms). In the process we generated Gigabar pressures only exceeded in the central hot spot of highly compressed thermonuclear fusion plasmas.. The plasma created after the dissolved wires expand, collide, and thermalize, is computed to have a thermal energy density of 0.3 GJ cm-3 and a pressure of 1-2 Gigabar. These are pressures only exceeded in highly compressed thermonuclear fusion plasmas. Scaling these results to higher laser intensities promises to create plasmas with temperatures and pressures exceeding those in the center of the sun.

  14. High density operation for reactor-relevant power exhaust

    Science.gov (United States)

    Wischmeier, M.

    2015-08-01

    With increasing size of a tokamak device and associated fusion power gain an increasing power flux density towards the divertor needs to be handled. A solution for handling this power flux is crucial for a safe and economic operation. Using purely geometric arguments in an ITER-like divertor this power flux can be reduced by approximately a factor 100. Based on a conservative extrapolation of current technology for an integrated engineering approach to remove power deposited on plasma facing components a further reduction of the power flux density via volumetric processes in the plasma by up to a factor of 50 is required. Our current ability to interpret existing power exhaust scenarios using numerical transport codes is analyzed and an operational scenario as a potential solution for ITER like divertors under high density and highly radiating reactor-relevant conditions is presented. Alternative concepts for risk mitigation as well as strategies for moving forward are outlined.

  15. Origins and Impacts of High-Density Symmetry Energy

    CERN Document Server

    Li, Bao-An

    2016-01-01

    What is nuclear symmetry energy? Why is it important? What do we know about it? Why is it so uncertain especially at high densities? Can the total symmetry energy or its kinetic part be negative? What are the effects of three-body and/or tensor force on symmetry energy? How can we probe the density dependence of nuclear symmetry energy with terrestrial nuclear experiments? What observables of heavy-ion reactions are sensitive to the high-density behavior of nuclear symmetry energy? How does the symmetry energy affect properties of neutron stars, gravitational waves and our understanding about the nature of strong-field gravity? In this lecture, we try to answer these questions as best as we can based on some of our recent work and/or understanding of research done by others. This note summarizes the main points of the lecture.

  16. Preparation of spherical cobalt carbonate powder with high tap density

    Institute of Scientific and Technical Information of China (English)

    XIAO Jin; WANG Jian-feng; LIU Yong-dong; LI Jie; LIU Ye-xiang

    2006-01-01

    Spherical cobalt carbonate with high tap density, good crystallization and uniform particle size was prepared by controlled chemical crystal method using cobalt chloride and ammonium bicarbonate as cobalt source and precipitator. The effects of pH value and reaction time on crystallization and physical properties of cobalt carbonate were studied. The results show that the key factors influencing the preparation process of spherical cobalt carbonate with high tap density and good crystallization are how to control pH value (7.25 ± 0.05) and keep some reaction time (about 10 h). Co4O3 was prepared by sintering spherical morphology CoCO3 samples at varied temperatures. The results show that as the decomposition temperature increases, the as-obtained Co4O3 products with porous structure transform into polyhedral structure with glazed surface, and simultaneously the cobalt content and tap density increase. However, the specific surface area shows a trend of decrease.

  17. 21 CFR 870.1230 - Fiberoptic oximeter catheter.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Fiberoptic oximeter catheter. 870.1230 Section 870...) MEDICAL DEVICES CARDIOVASCULAR DEVICES Cardiovascular Diagnostic Devices § 870.1230 Fiberoptic oximeter catheter. (a) Identification. A fiberoptic oximeter catheter is a device used to estimate the...

  18. 21 CFR 876.4530 - Gastroenterology-urology fiberoptic retractor.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Gastroenterology-urology fiberoptic retractor. 876... SERVICES (CONTINUED) MEDICAL DEVICES GASTROENTEROLOGY-UROLOGY DEVICES Surgical Devices § 876.4530 Gastroenterology-urology fiberoptic retractor. (a) Identification. A gastroenterology-urology fiberoptic...

  19. Theoretical Study on the High Energy Density Compound Hexanitrohexaazatricyclotetradecanedifuroxan

    Institute of Scientific and Technical Information of China (English)

    QIU Ling; XIAO He-Ming; ZHU Wei-Hua; JU Xue-Hai; GONG Xue-Dong

    2006-01-01

    Density functional theory (DFT) has been employed to study the molecular geometries, electronic structures,infrared (IR) spectra, and thermodynamic properties of the high energy density compound hexanitrohexaazatricyclotetradecanedifuroxan (HHTTD) at the B3LYP/6-31G** level of theory. The calculated results showthattherearefourconformationalisomers (a, β, γ and δ) for HHTTD, and the relative stabilities of four conformers were assessed based on the calculated total energies and the energy-gaps between the frontier molecular orbitals. The computed harmonic vibrational frequencies are in reasonable agreement with the available experimental data. Thermodynamic properties derived from the IR spectra on the basis of statistical thermodynamic principles are linearly correlated with the temperature. Detonation performances were evaluated by using the Kamlet-Jacobsequationsbasedonthecalculated densities and heats of formation. It was found that four HHTTD isomers with the predicted densities of ca. 2 g·cm-3, detonation velocities near 10 km·s-1, and detonation pressures over 45 Gpa, may be novel potential candidates of high energy density materials (HEDM). These results may provide basic information for the molecular designof HEDM.

  20. A high energy density relaxor antiferroelectric pulsed capacitor dielectric

    Energy Technology Data Exchange (ETDEWEB)

    Jo, Hwan Ryul; Lynch, Christopher S. [Department of Mechanical and Aerospace Engineering, University of California, Los Angeles (UCLA), Los Angeles, California 90095 (United States)

    2016-01-14

    Pulsed capacitors require high energy density and low loss, properties that can be realized through selection of composition. Ceramic (Pb{sub 0.88}La{sub 0.08})(Zr{sub 0.91}Ti{sub 0.09})O{sub 3} was found to be an ideal candidate. La{sup 3+} doping and excess PbO were used to produce relaxor antiferroelectric behavior with slim and slanted hysteresis loops to reduce the dielectric hysteresis loss, to increase the dielectric strength, and to increase the discharge energy density. The discharge energy density of this composition was found to be 3.04 J/cm{sup 3} with applied electric field of 170 kV/cm, and the energy efficiency, defined as the ratio of the discharge energy density to the charging energy density, was 0.920. This high efficiency reduces the heat generated under cyclic loading and improves the reliability. The properties were observed to degrade some with temperature increase above 80 °C. Repeated electric field cycles up to 10 000 cycles were applied to the specimen with no observed performance degradation.

  1. A high current density DC magnetohydrodynamic (MHD) micropump

    NARCIS (Netherlands)

    Homsy, Alexandra; Koster, Sander; Eijkel, Jan C.T.; Berg, van den Albert; Lucklum, F.; Verpoorte, E.; Rooij, de Nico F.

    2005-01-01

    This paper describes the working principle of a DC magnetohydrodynamic (MHD) micropump that can be operated at high DC current densities (J) in 75-µm-deep microfluidic channels without introducing gas bubbles into the pumping channel. The main design feature for current generation is a micromachined

  2. A high current density DC magnetohydrodynamic (MHD) micropump

    NARCIS (Netherlands)

    Homsy, A; Koster, Sander; Eijkel, JCT; van den Berg, A; Lucklum, F; Verpoorte, E; de Rooij, NF

    2005-01-01

    This paper describes the working principle of a DC magnetohydrodynamic (MHD) micropump that can be operated at high DC current densities (J) in 75-mu m-deep microfluidic channels without introducing gas bubbles into the pumping channel. The main design feature for current generation is a micromachin

  3. Intraocular inflammation following endotamponade with high-density silicone oil.

    NARCIS (Netherlands)

    Theelen, T.; Tilanus, M.A.D.; Klevering, B.J.

    2004-01-01

    BACKGROUND: The use of a mixture of silicone oil and partially fluorinated alkanes (high-density silicone oil) has recently been suggested as intraocular tamponade in complicated retinal detachment of the inferior quadrants. We describe a series of patients who developed a clinical picture resemblin

  4. Two-Dimensional Super High Density Multi-Fiber Connector

    Institute of Scientific and Technical Information of China (English)

    Takashi Shigenaga; Katsuki Suematsu; Masao Shinoda; Takayuki Ando

    2003-01-01

    We have developed 32-fiber and 60-fiber super high density multi fiber connector. This 32-fiber connector can be applicable for single-mode fiber and 60-fiber connector for multi-mode fiber. We have also established PC (physical contact) connection technology by optimizing polishing condition and clamping force.

  5. Interaction effects in high density magnetic particulate media

    Energy Technology Data Exchange (ETDEWEB)

    Cerchez, Mihai; Stoleriu, Laurentiu; Stancu, Alexandru

    2004-01-01

    The paper presents a micromagnetic study of the particulate high density recording media. The main difference in the behavior of such a system is the appearance of magnetic clusters which lead to a different behavior of the system. New hypotheses for interpreting such systems are presented.

  6. Metabolism of high density lipoproteins in liver cancer

    Institute of Scientific and Technical Information of China (English)

    Jing-Ting Jiang; Ning Xu; Chang-Ping Wu

    2007-01-01

    Liver plays a vital role in the production and catabolism of plasma lipoproteins. It depends on the integrity of cellular function of liver, which ensures homeostasis of lipid and lipoprotein metabolism. When liver cancer occurs these processes are impaired and high-density lipoproteins are changed.

  7. High Energy Density Physics and Exotic Acceleration Schemes

    Science.gov (United States)

    Cowan, Thomas; Colby, Eric

    2002-12-01

    We summarize the reported results and the principal technical discussions that occurred in our Working Group on High Energy Density Physics and Exotic Acceleration Schemes at the 2002 workshop on Advanced Accelerator Concepts at the Mandalay Beach resort, June 22-28, 2002.

  8. Intraocular inflammation following endotamponade with high-density silicone oil.

    NARCIS (Netherlands)

    Theelen, T.; Tilanus, M.A.D.; Klevering, B.J.

    2004-01-01

    BACKGROUND: The use of a mixture of silicone oil and partially fluorinated alkanes (high-density silicone oil) has recently been suggested as intraocular tamponade in complicated retinal detachment of the inferior quadrants. We describe a series of patients who developed a clinical picture

  9. A Novel Anti-Inflammatory Effect for High Density Lipoprotein.

    Directory of Open Access Journals (Sweden)

    Scott J Cameron

    Full Text Available High density lipoprotein has anti-inflammatory effects in addition to mediating reverse cholesterol transport. While many of the chronic anti-inflammatory effects of high density lipoprotein (HDL are attributed to changes in cell adhesion molecules, little is known about acute signal transduction events elicited by HDL in endothelial cells. We now show that high density lipoprotein decreases endothelial cell exocytosis, the first step in leukocyte trafficking. ApoA-I, a major apolipoprotein of HDL, mediates inhibition of endothelial cell exocytosis by interacting with endothelial scavenger receptor-BI which triggers an intracellular protective signaling cascade involving protein kinase C (PKC. Other apolipoproteins within the HDL particle have only modest effects upon endothelial exocytosis. Using a human primary culture of endothelial cells and murine apo-AI knockout mice, we show that apo-AI prevents endothelial cell exocytosis which limits leukocyte recruitment. These data suggest that high density lipoprotein may inhibit diseases associated with vascular inflammation in part by blocking endothelial exocytosis.

  10. High follicle density does not decrease sweat gland density in Huacaya alpacas.

    Science.gov (United States)

    Moore, K E; Maloney, S K; Blache, D

    2015-01-01

    When exposed to high ambient temperatures, mammals lose heat evaporatively by either sweating from glands in the skin or by respiratory panting. Like other camelids, alpacas are thought to evaporate more water by sweating than panting, despite a thick fleece, unlike sheep which mostly pant in response to heat stress. Alpacas were brought to Australia to develop an alternative fibre industry to sheep wool. In Australia, alpacas can be exposed to ambient temperatures higher than in their native South America. As a young industry there is a great deal of variation in the quality and quantity of the fleece produced in the national flock. There is selection pressure towards animals with finer and denser fleeces. Because the fibre from secondary follicles is finer than that from primary follicles, selecting for finer fibres might alter the ratio of primary and secondary follicles. In turn the selection might alter sweat gland density because the sweat glands are associated with the primary follicle. Skin biopsy and fibre samples were obtained from the mid-section of 33 Huacaya alpacas and the skin sections were processed into horizontal sections at the sebaceous gland level. Total, primary, and secondary follicles and the number of sweat gland ducts were quantified. Fibre samples from each alpaca were further analysed for mean fibre diameter. The finer-fibred animals had a higher total follicle density (P<0.001) and more sweat glands (P<0.001) than the thicker-fibred animals. The fibre diameter and total follicle density were negatively correlated (R(2)=0.56, P<0.001). Given that the finer-fibred animals had higher follicle density and more sweat glands than animals with thicker fibres, we conclude that alpacas with high follicle density should not be limited for potential sweating ability. Copyright © 2014 Elsevier Ltd. All rights reserved.

  11. Interfacial Tension and Surface Pressure of High Density Lipoprotein, Low Density Lipoprotein, and Related Lipid Droplets

    DEFF Research Database (Denmark)

    Ollila, O. H. S.; Lamberg, A.; Lehtivaara, M.

    2012-01-01

    Lipid droplets play a central role in energy storage and metabolism on a cellular scale. Their core is comprised of hydrophobic lipids covered by a surface region consisting of amphiphilic lipids and proteins. For example, high and low density lipoproteins (HDL and LDL, respectively) are essentia...... of interfacial tension becomes significant for particles with a radius of similar to 5 nm, when the area per molecule in the surface region is...

  12. Extreme states of matter high energy density physics

    CERN Document Server

    Fortov, Vladimir E

    2016-01-01

    With its many beautiful colour pictures, this book gives fascinating insights into the unusual forms and behaviour of matter under extremely high pressures and temperatures. These extreme states are generated, among other things, by strong shock, detonation and electric explosion waves, dense laser beams,electron and ion beams, hypersonic entry of spacecraft into dense atmospheres of planets, and in many other situations characterized by extremely high pressures and temperatures.Written by one of the world's foremost experts on the topic, this book will inform and fascinate all scientists dealing with materials properties and physics, and also serve as an excellent introduction to plasma-, shock-wave and high-energy-density physics for students and newcomers seeking an overview. This second edition is thoroughly revised and expanded, in particular with new material on high energy-density physics, nuclear explosions and other nuclear transformation processes.

  13. Quark Matter at High Density based on Extended Confined-isospin-density-dependent-mass Model

    CERN Document Server

    Qauli, A I

    2016-01-01

    We investigate the effect of the inclusion of relativistic Coulomb terms in a confined-isospin-density-dependent-mass (CIDDM) model of strange quark matter (SQM). We found that if we include Coulomb term in scalar density form, SQM equation of state (EOS) at high densities is stiffer but if we include Coulomb term in vector density form is softer than that of standard CIDDM model. We also investigate systematically the role of each term of the extended CIDDM model. Compared with what was reported in Ref.~\\cite {ref:isospin}, we found the stiffness of SQM EOS is controlled by the interplay among the the oscillator harmonic, isospin asymmetry and Coulomb contributions depending on the parameter's range of these terms. We have found that the absolute stable condition of SQM and the mass of 2 $M_\\odot$ pulsars can constrain the parameter of oscillator harmonic $\\kappa_1$ $\\approx 0.53$ in the case Coulomb term excluded. If the Coulomb term is included, for the models with their parameters are consistent with SQM ...

  14. High-Density Stacked Ru Nanocrystals for Nonvolatile Memory Application

    Institute of Scientific and Technical Information of China (English)

    MAO Ping; ZHANG Zhi-Gang; PAN Li-Yang; XU Jun; CHEN Pei-Yi

    2009-01-01

    @@ Stacked ruthenium (Ru) nanocrystals (NCs) are formed by rapid thermal annealing for the whole gate stacks and embedded in memory structure, which is compatible with conventional CMOS technology. Ru NCs with high density (3×1012 cm-2 ), small size (2-4 nm) and good uniformity both in aerial distribution and morphology are formed. Attributed to the higher surface trap density, a memory window of 5.2 V is obtained with stacked Ru NCs in comparison to that of 3.5 V with single-layer samples. The stacked Ru NCs device also exhibits much better retention performance because of Coulomb blockade and vertical uniformity between stacked Ru NCs.

  15. Calibration and deployment of a fiber-optic sensing system for monitoring debris flows.

    Science.gov (United States)

    Huang, Ching-Jer; Chu, Chung-Ray; Tien, Tsung-Mo; Yin, Hsiao-Yuen; Chen, Ping-Sen

    2012-01-01

    This work presents a novel fiber-optic sensing system, capable of monitoring debris flows or other natural hazards that produce ground vibrations. The proposed sensing system comprises a demodulator (BraggSCOPE, FS5500), which includes a broadband light source and a data logger, a four-port coupler and four Fiber Bragg Grating (FBG) accelerometers. Based on field tests, the performance of the proposed fiber-optic sensing system is compared with that of a conventional sensing system that includes a geophone or a microphone. Following confirmation of the reliability of the proposed sensing system, the fiber-optic sensing systems are deployed along the Ai-Yu-Zi and Chu-Shui Creeks in Nautou County of central Taiwan for monitoring debris flows. Sensitivity test of the deployed fiber-optic sensing system along the creek banks is also performed. Analysis results of the seismic data recorded by the systems reveal in detail the frequency characteristics of the artificially generated ground vibrations. Results of this study demonstrate that the proposed fiber-optic sensing system is highly promising for use in monitoring natural disasters that generate ground vibrations.

  16. High-Sensitivity Measurement of Density by Magnetic Levitation.

    Science.gov (United States)

    Nemiroski, Alex; Kumar, A A; Soh, Siowling; Harburg, Daniel V; Yu, Hai-Dong; Whitesides, George M

    2016-03-01

    This paper presents methods that use Magnetic Levitation (MagLev) to measure very small differences in density of solid diamagnetic objects suspended in a paramagnetic medium. Previous work in this field has shown that, while it is a convenient method, standard MagLev (i.e., where the direction of magnetization and gravitational force are parallel) cannot resolve differences in density mm) because (i) objects close in density prevent each other from reaching an equilibrium height due to hard contact and excluded volume, and (ii) using weaker magnets or reducing the magnetic susceptibility of the medium destabilizes the magnetic trap. The present work investigates the use of weak magnetic gradients parallel to the faces of the magnets as a means of increasing the sensitivity of MagLev without destabilization. Configuring the MagLev device in a rotated state (i.e., where the direction of magnetization and gravitational force are perpendicular) relative to the standard configuration enables simple measurements along the axes with the highest sensitivity to changes in density. Manipulating the distance of separation between the magnets or the lengths of the magnets (along the axis of measurement) enables the sensitivity to be tuned. These modifications enable an improvement in the resolution up to 100-fold over the standard configuration, and measurements with resolution down to 10(-6) g/cm(3). Three examples of characterizing the small differences in density among samples of materials having ostensibly indistinguishable densities-Nylon spheres, PMMA spheres, and drug spheres-demonstrate the applicability of rotated Maglev to measuring the density of small (0.1-1 mm) objects with high sensitivity. This capability will be useful in materials science, separations, and quality control of manufactured objects.

  17. Rf Gun with High-Current Density Field Emission Cathode

    Energy Technology Data Exchange (ETDEWEB)

    Jay L. Hirshfield

    2005-12-19

    High current-density field emission from an array of carbon nanotubes, with field-emission-transistor control, and with secondary electron channel multiplication in a ceramic facing structure, have been combined in a cold cathode for rf guns and diode guns. Electrodynamic and space-charge flow simulations were conducted to specify the cathode configuration and range of emission current density from the field emission cold cathode. Design of this cathode has been made for installation and testing in an existing S-band 2-1/2 cell rf gun. With emission control and modulation, and with current density in the range of 0.1-1 kA/cm2, this cathode could provide performance and long-life not enjoyed by other currently-available cathodes

  18. Collapsing Bubble in Metal for High Energy Density Physics Study

    Energy Technology Data Exchange (ETDEWEB)

    Ng, S F; Barnard, J J; Leung, P T; Yu, S S

    2011-04-13

    This paper presents a new idea to produce matter in the high energy density physics (HEDP) regime in the laboratory using an intense ion beam. A gas bubble created inside a solid metal may collapse by driving it with an intense ion beam. The melted metal will compress the gas bubble and supply extra energy to it. Simulations show that the spherical implosion ratio can be about 5 and at the stagnation point, the maximum density, temperature and pressure inside the gas bubble can go up to nearly 2 times solid density, 10 eV and a few megabar (Mbar) respectively. The proposed experiment is the first to permit access into the Mbar regime with existing or near-term ion facilities, and opens up possibilities for new physics gained through careful comparisons of simulations with measurements of quantities like stagnation radius, peak temperature and peak pressure at the metal wall.

  19. Indication for fiberoptic bronchoscopy in HIV-infected patients suspected for Pneumocystis carinii pneumonia

    DEFF Research Database (Denmark)

    Orholm, M; Lundgren, Jens Dilling; Nielsen, T L;

    1990-01-01

    During a six-month period, 40 consecutive fiberoptic bronchoscopic procedures including bronchoalveolar lavage, bronchial brushing and forceps biopsy were performed in local anaesthesia on 34 HIV-infected males presenting symptoms compatible with Pneumocystis carinii pneumonia. In 23 examinations...... did not differ with regard to history, clinical examination, immunology, serology or chest radiograph. We conclude that fiberoptic bronchoscopy should be performed on wide indications in HIV-infected patients with symptoms compatible with P. carinii pneumonia. The procedure is easily performed......, it is safe, and it is highly sensitive. The advantage of an early diagnosis compensates for a rather high frequency of negative examinations....

  20. Mobile fiber-optic laser Doppler anemometer.

    Science.gov (United States)

    Stieglmeier, M; Tropea, C

    1992-07-20

    A laser Doppler anemometer (LDA) has been developed that combines the compactness and low power consumption of laser diodes and avalanche photodiodes with the flexibility and possibility of miniaturization by using fiber-optic probes. The system has been named DFLDA for laser diode fiber LDA and is especially suited for mobile applications, for example, in trains, airplanes, or automobiles. Optimization considerations of fiber-optic probes are put forward and several probe examples are described in detail. Measurement results from three typical applications are given to illustrate the use of the DFLDA. Finally, a number of future configurations of the DFLDA concept are discussed.

  1. High energy-density science on the National Ignition Facility

    Energy Technology Data Exchange (ETDEWEB)

    Campbell, E.M.; Cauble, R.; Remington, B.A.

    1997-08-01

    The National Ignition Facility, as well as its French counterpart Le Laser Megajoule, have been designed to confront one of the most difficult and compelling problem in shock physics - the creation of a hot, compassed DT plasma surrounded and confined by cold, nearly degenerate DT fuel. At the same time, these laser facilities will present the shock physics community with unique tools for the study of high energy density matter at states unreachable by any other laboratory technique. Here we describe how these lasers can contribute to investigations of high energy density in the area of material properties and equations of state, extend present laboratory shock techniques such as high-speed jets to new regimes, and allow study of extreme conditions found in astrophysical phenomena.

  2. Rationally designed polyimides for high-energy density capacitor applications.

    Science.gov (United States)

    Ma, Rui; Baldwin, Aaron F; Wang, Chenchen; Offenbach, Ido; Cakmak, Mukerrem; Ramprasad, Rampi; Sotzing, Gregory A

    2014-07-01

    Development of new dielectric materials is of great importance for a wide range of applications for modern electronics and electrical power systems. The state-of-the-art polymer dielectric is a biaxially oriented polypropylene (BOPP) film having a maximal energy density of 5 J/cm(3) and a high breakdown field of 700 MV/m, but with a limited dielectric constant (∼2.2) and a reduced breakdown strength above 85 °C. Great effort has been put into exploring other materials to fulfill the demand of continuous miniaturization and improved functionality. In this work, a series of polyimides were investigated as potential polymer materials for this application. Polyimide with high dielectric constants of up to 7.8 that exhibits low dissipation factors (<1%) and high energy density around 15 J/cm(3), which is 3 times that of BOPP, was prepared. Our syntheses were guided by high-throughput density functional theory calculations for rational design in terms of a high dielectric constant and band gap. Correlations of experimental and theoretical results through judicious variations of polyimide structures allowed for a clear demonstration of the relationship between chemical functionalities and dielectric properties.

  3. Average density and porosity of high-strength lightweight concrete

    Directory of Open Access Journals (Sweden)

    A.S. Inozemtcev

    2014-11-01

    Full Text Available The analysis results of high-strength lightweight concrete (HSLWC structure are presented in this paper. The X-ray tomography, optical microscopy and other methods are used for researching of average density and porosity. It has been revealed that mixtures of HSLWC with density 1300…1500 kg/m3 have a homogeneous structure. The developed concrete has a uniform distribution of the hollow filler and a uniform layer of cement-mineral matrix. The highly saturated gas phase which is divided by denser large particles of quartz sand and products of cement hydration in the contact area allow forming a composite material with low average density, big porosity (up to 40% and high strength (compressive strength is more than 40 MPa. Special modifiers increase adhesion, compacts structure in the contact area, decrease water absorption of high-strength lightweight concrete (up to 1 % and ensure its high water resistance (water resistance coefficient is more than 0.95.

  4. High power density yeast catalyzed microbial fuel cells

    Science.gov (United States)

    Ganguli, Rahul

    Microbial fuel cells leverage whole cell biocatalysis to convert the energy stored in energy-rich renewable biomolecules such as sugar, directly to electrical energy at high efficiencies. Advantages of the process include ambient temperature operation, operation in natural streams such as wastewater without the need to clean electrodes, minimal balance-of-plant requirements compared to conventional fuel cells, and environmentally friendly operation. These make the technology very attractive as portable power sources and waste-to-energy converters. The principal problem facing the technology is the low power densities compared to other conventional portable power sources such as batteries and traditional fuel cells. In this work we examined the yeast catalyzed microbial fuel cell and developed methods to increase the power density from such fuel cells. A combination of cyclic voltammetry and optical absorption measurements were used to establish significant adsorption of electron mediators by the microbes. Mediator adsorption was demonstrated to be an important limitation in achieving high power densities in yeast-catalyzed microbial fuel cells. Specifically, the power densities are low for the length of time mediator adsorption continues to occur. Once the mediator adsorption stops, the power densities increase. Rotating disk chronoamperometry was used to extract reaction rate information, and a simple kinetic expression was developed for the current observed in the anodic half-cell. Since the rate expression showed that the current was directly related to microbe concentration close to the electrode, methods to increase cell mass attached to the anode was investigated. Electrically biased electrodes were demonstrated to develop biofilm-like layers of the Baker's yeast with a high concentration of cells directly connected to the electrode. The increased cell mass did increase the power density 2 times compared to a non biofilm fuel cell, but the power density

  5. High energy density capacitors for low cost applications

    Science.gov (United States)

    Iyore, Omokhodion David

    Polyvinylidene fluoride (PVDF) and its copolymers with trifluoroethylene, hexafluoropropylene and chlorotrifluoroethylene are the most widely investigated ferroelectric polymers, due to their relatively high electromechanical properties and potential to achieve high energy density. [Bauer, 2010; Zhou et al., 2009] The research community has focused primarily on melt pressed or extruded films of PVDF-based polymers to obtain the highest performance with energy density up to 25 Jcm-3. [Zhou et al., 2009] Solution processing offers an inexpensive, low temperature alternative, which is also easily integrated with flexible electronics. This dissertation focuses on the fabrication of solution-based polyvinylidene fluoride-hexafluoropropylene metal-insulator-metal capacitors on flexible substrates using a photolithographic process. Capacitors were optimized for maximum energy density, high dielectric strength and low leakage current density. It is demonstrated that with the right choice of solvent, electrodes, spin-casting and annealing conditions, high energy density thin film capacitors can be fabricated repeatably and reproducibly. The high electric field dielectric constants were measured and the reliabilities of the polymer capacitors were also evaluated via time-zero breakdown and time-dependent breakdown techniques. Chapter 1 develops the motivation for this work and provides a theoretical overview of dielectric materials, polarization, leakage current and dielectric breakdown. Chapter 2 is a literature review of polymer-based high energy density dielectrics and covers ferroelectric polymers, highlighting PVDF and some of its derivatives. Chapter 3 summarizes some preliminary experimental work and presents materials and electrical characterization that support the rationale for materials selection and process development. Chapter 4 discusses the fabrication of solution-processed PVDF-HFP and modification of its properties by photo-crosslinking. It is followed by a

  6. The High Density Region of QCD from an Effective Model

    CERN Document Server

    De Pietri, R; Seiler, E; Stamatescu, I O

    2007-01-01

    We study the high density region of QCD within an effective model obtained in the frame of the hopping parameter expansion and choosing Polyakov-type loops as the main dynamical variables representing the fermionic matter. This model still shows the so-called sign problem, a difficulty peculiar to non-zero chemical potential, but it permits the development of algorithms which ensure a good overlap of the simulated Monte Carlo ensemble with the true one. We review the main features of the model and present results concerning the dependence of various observables on the chemical potential and on the temperature, in particular of the charge density and the Polykov loop susceptibility, which may be used to characterize the various phases expected at high baryonic density. In this way, we obtain information about the phase structure of the model and the corresponding phase transitions and cross over regions, which can be considered as hints about the behaviour of non-zero density QCD.

  7. High Energy Density Regenerative Fuel Cell Systems for Terrestrial Applications

    Science.gov (United States)

    Burke, Kenneth A.

    1999-01-01

    Regenerative Fuel Cell System (RFCS) technology for energy storage has been a NASA power system concept for many years. Compared to battery-based energy storage systems, RFCS has received relatively little attention or resources for development because the energy density and electrical efficiency were not sufficiently attractive relative to advanced battery systems. Even today, RFCS remains at a very low technology readiness level (TRL of about 2 indicating feasibility has been demonstrated). Commercial development of the Proton Exchange Membrane (PEM) fuel cells for automobiles and other terrestrial applications and improvements in lightweight pressure vessel design to reduce weight and improve performance make possible a high energy density RFCS energy storage system. The results from this study of a lightweight RFCS energy storage system for a remotely piloted, solar-powered, high altitude aircraft indicate an energy density up to 790 w-h/kg with electrical efficiency of 53.4% is attainable. Such an energy storage system would allow a solar-powered aircraft to carry hundreds of kilograms of payload and remain in flight indefinitely for use in atmospheric research, earth observation, resource mapping. and telecommunications. Future developments in the areas of hydrogen and oxygen storage, pressure vessel design, higher temperature and higher- pressure fuel cell operation, unitized regenerative fuel cells, and commercial development of fuel cell technology will improve both the energy density and electrical efficiency of the RFCS.

  8. High-density housing that works for all

    Energy Technology Data Exchange (ETDEWEB)

    Hasan, Arif

    2010-03-15

    In an urbanising world, the way people fit into cities is vastly important - socially, economically, environmentally, even psychologically. So density, or the number of people living in a given area, is central to urban design and planning. Both governments and markets tend to get density wrong, leading to overcrowding, urban sprawl or often both. A case in point are the high-rise buildings springing up throughtout urban Asia - perceived as key features of that widely touted concept, the 'world-class city'. While some may offer a viable solution to land pressures and density requirements, many built to house evicted or resettled 'slum' dwellers are a social and economic nightmare - inconveniently sited, overcrowded and costly. New evidence from Karachi, Pakistan, reveals a real alternative. Poor people can create liveable high-density settlements as long as community control, the right technical assistance and flexible designs are in place. A city is surely 'world-class' only when it is cosmopolitan – built to serve all, including the poorest.

  9. Design of High Power Density Amplifiers: Application to Ka Band

    Science.gov (United States)

    Passi, Davide; Leggieri, Alberto; Di Paolo, Franco; Bartocci, Marco; Tafuto, Antonio

    2017-06-01

    Recent developments in the design of high-power-high-frequency amplifiers are assessed in this paper by the analysis and measurements of a high power density amplifier operating in the Ka Band. Design procedure is presented and a technical investigation is reported. The proposed device has shown over 23% of useful frequency bandwidth. It is an ensemble of 16 monolithic solid state power amplifiers that employees mixed technologies as spatial and planar combiners. Test performed have given maximum delivered power of 47.2 dBm.

  10. Fiber-Optic Network Architectures for Onboard Avionics Applications Investigated

    Science.gov (United States)

    Nguyen, Hung D.; Ngo, Duc H.

    2003-01-01

    This project is part of a study within the Advanced Air Transportation Technologies program undertaken at the NASA Glenn Research Center. The main focus of the program is the improvement of air transportation, with particular emphasis on air transportation safety. Current and future advances in digital data communications between an aircraft and the outside world will require high-bandwidth onboard communication networks. Radiofrequency (RF) systems, with their interconnection network based on coaxial cables and waveguides, increase the complexity of communication systems onboard modern civil and military aircraft with respect to weight, power consumption, and safety. In addition, safety and reliability concerns from electromagnetic interference between the RF components embedded in these communication systems exist. A simple, reliable, and lightweight network that is free from the effects of electromagnetic interference and capable of supporting the broadband communications needs of future onboard digital avionics systems cannot be easily implemented using existing coaxial cable-based systems. Fiber-optical communication systems can meet all these challenges of modern avionics applications in an efficient, cost-effective manner. The objective of this project is to present a number of optical network architectures for onboard RF signal distribution. Because of the emergence of a number of digital avionics devices requiring high-bandwidth connectivity, fiber-optic RF networks onboard modern aircraft will play a vital role in ensuring a low-noise, highly reliable RF communication system. Two approaches are being used for network architectures for aircraft onboard fiber-optic distribution systems: a hybrid RF-optical network and an all-optical wavelength division multiplexing (WDM) network.

  11. Fiber-optic analog-to-NRZ binary conversion

    Science.gov (United States)

    Siahmakoun, A.; Reeves, E.

    2015-03-01

    A novel photonic analog-to-binary converter based on the first-order asynchronous delta-sigma modulation (ADSM) has been theoretically investigated and experimentally demonstrated. A fiber-optic prototype ADSM system is constructed and characterized. Delta-sigma modulation is a straightforward approach to A/D conversion because in this case an external clocking is not required and demodulation can be simply performed via a low-pass filtering process. To improve signal-to-noise ratio and thus system ENOB, a non-interferometric optical implementation has been constructed. The ADSM is comprised of three photonic devices: an inverted output photonic leaky integrator, bistable quantizer, and positive corrective feedback. The photonic integrator which is a recirculating loop performs the oversampling of an analog input using the cross-gain modulation in an SOA. We will show that the photonic ADSM produces an inverted non-return-to-zero (NRZ) pulse-density modulated output describing an input analog signal. This fiber-optic ADSM converts up to 7.6 MHz analog input at about 30 MS/s and effective ENOB of 6.

  12. The use of low density high accuracy (LDHA) data for correction of high density low accuracy (HDLA) point cloud

    Science.gov (United States)

    Rak, Michal Bartosz; Wozniak, Adam; Mayer, J. R. R.

    2016-06-01

    Coordinate measuring techniques rely on computer processing of coordinate values of points gathered from physical surfaces using contact or non-contact methods. Contact measurements are characterized by low density and high accuracy. On the other hand optical methods gather high density data of the whole object in a short time but with accuracy at least one order of magnitude lower than for contact measurements. Thus the drawback of contact methods is low density of data, while for non-contact methods it is low accuracy. In this paper a method for fusion of data from two measurements of fundamentally different nature: high density low accuracy (HDLA) and low density high accuracy (LDHA) is presented to overcome the limitations of both measuring methods. In the proposed method the concept of virtual markers is used to find a representation of pairs of corresponding characteristic points in both sets of data. In each pair the coordinates of the point from contact measurements is treated as a reference for the corresponding point from non-contact measurement. Transformation enabling displacement of characteristic points from optical measurement to their match from contact measurements is determined and applied to the whole point cloud. The efficiency of the proposed algorithm was evaluated by comparison with data from a coordinate measuring machine (CMM). Three surfaces were used for this evaluation: plane, turbine blade and engine cover. For the planar surface the achieved improvement was of around 200 μm. Similar results were obtained for the turbine blade but for the engine cover the improvement was smaller. For both freeform surfaces the improvement was higher for raw data than for data after creation of mesh of triangles.

  13. A Tale of Two Electrons: Correlation at High Density

    CERN Document Server

    Loos, Pierre-François

    2010-01-01

    We review our recent progress in the determination of the high-density correlation energy $\\Ec$ in two-electron systems. Several two-electron systems are considered, such as the well known helium-like ions (helium), and the Hooke's law atom (hookium). We also present results regarding two electrons on the surface of a sphere (spherium), and two electrons trapped in a spherical box (ballium). We also show that, in the large-dimension limit, the high-density correlation energy of two opposite-spin electrons interacting {\\em via} a Coulomb potential is given by $\\Ec \\sim -1/(8D^2)$ for any radial external potential $V(r)$, where $D$ is the dimensionality of the space. This result explains the similarity of $\\Ec$ in the previous two-electron systems for $D=3$.

  14. Lithium-Based High Energy Density Flow Batteries

    Science.gov (United States)

    Bugga, Ratnakumar V. (Inventor); West, William C. (Inventor); Kindler, Andrew (Inventor); Smart, Marshall C. (Inventor)

    2014-01-01

    Systems and methods in accordance with embodiments of the invention implement a lithium-based high energy density flow battery. In one embodiment, a lithium-based high energy density flow battery includes a first anodic conductive solution that includes a lithium polyaromatic hydrocarbon complex dissolved in a solvent, a second cathodic conductive solution that includes a cathodic complex dissolved in a solvent, a solid lithium ion conductor disposed so as to separate the first solution from the second solution, such that the first conductive solution, the second conductive solution, and the solid lithium ionic conductor define a circuit, where when the circuit is closed, lithium from the lithium polyaromatic hydrocarbon complex in the first conductive solution dissociates from the lithium polyaromatic hydrocarbon complex, migrates through the solid lithium ionic conductor, and associates with the cathodic complex of the second conductive solution, and a current is generated.

  15. Self-assembled random arrays: high-performance imaging and genomics applications on a high-density microarray platform

    Science.gov (United States)

    Barker, David L.; Theriault, Greg; Che, Diping; Dickinson, Todd; Shen, Richard; Kain, Robert C.

    2003-07-01

    Illumina is developing a BeadArrayTM technology that supports SNP genotyping, mRNA expression analysis and protein expression analysis on the same platform. We use fiber-optic bundles with a density of approximately 40,000 fibers/mm2. At hte end of each fiber, a derivatized silica bead forms an array element for reading out a genotyping or expression assay data point. Each bead contains oligonucleotide probes that hybridize with high specificity to complementary sequences in a complex nucleic acid mixture. We derivatize the beads in bulk, pool them to form a quality-controlled source of microarray elements, and allow them to assemble spontaneously into pits etched into the end of each optical fiber bundle. We load our fiber bundles, containing 49,777 fibers, with up to 1520 different bead types. The presence of many beads of each type greatly improves the accuracy of each assay. As the final step in our manufacturing process, we decode the identity of each bead by a series of rapid hybridizations with fluroescent oligos. Decoding accuracy and the number of beads of each type is recorded for each array. Decoding also serves as a quality control procedure for the performance of each element in the array. To facilitate high-throughput analysis of many samples, the fiber bundles are arranged in an array matrix (SentrixTM arrays). Using a 96-bundle array matrix, up to 1520 assays can be performed on each of 96 samples simultaneously for a total of 145,920 assays. Using a 384-bundle array matrix, up to 583,680 assays can be performed simultaneously. The BeadArray platform is the highest density microarray in commercial use, requiring development of a high-performance array scanner. To meet this need, we developed the SherlockTM system, a laser-scanning confocal imaging system that automatically scans all 96 bundles of an array matrix at variable resolution down to 0.8 micron. The system scans with both 532 and 635 nm lasers simultaneously, collecting two fluorescence

  16. High energy density capacitor testing for the AFWL SHIVA

    Science.gov (United States)

    Smith, D. L.; Reinovsky, R. E.

    Lifetime testing and analysis of small samples of high energy density (HED) discharge capacitors at the AFWL were conducted to find a component suitable for upgrading the SHIVA capacitor bank to a 6 MJ facility. Evaluation was performed with discharge conditions of approximately 250 kA per capacitor at 60 to 70% reversal and 2 microsec quarter period. Dielectric systems including Kraft paper with caster oil impregnant and Kraft paper, polypropylene with DiOctyl Phthalate (DOP) impregnant were tested.

  17. Polypropylene-(high density polyethylene) precipitation from stirred solutions

    OpenAIRE

    Esperidião,Maria Cecília Azevedo; Galembeck,Fernando

    1993-01-01

    Texto completo: acesso restrito. p.993–997 The fast precipitation of mixtures of polypropylene (PP) with high density polyethylene (HDPE) from decalin solutions is affected by the stirring rate of the solutions. With fast stirring, two types of precipitates were obtained viz. globules dispersed in the liquid phase and fibres adhering to the stirrer. Studies by i.r., WAXD, DSC and optical microscopy indicated that the fibrous precipitate is more birefringent, richer in HDPE and richer in th...

  18. Flexible and Lightweight Fuel Cell with High Specific Power Density.

    Science.gov (United States)

    Ning, Fandi; He, Xudong; Shen, Yangbin; Jin, Hehua; Li, Qingwen; Li, Da; Li, Shuping; Zhan, Yulu; Du, Ying; Jiang, Jingjing; Yang, Hui; Zhou, Xiaochun

    2017-06-27

    Flexible devices have been attracting great attention recently due to their numerous advantages. But the energy densities of current energy sources are still not high enough to support flexible devices for a satisfactory length of time. Although proton exchange membrane fuel cells (PEMFCs) do have a high-energy density, traditional PEMFCs are usually too heavy, rigid, and bulky to be used in flexible devices. In this research, we successfully invented a light and flexible air-breathing PEMFC by using a new design of PEMFC and a flexible composite electrode. The flexible air-breathing PEMFC with 1 × 1 cm(2) working area can be as light as 0.065 g and as thin as 0.22 mm. This new PEMFC exhibits an amazing specific volume power density as high as 5190 W L(-1), which is much higher than traditional (air-breathing) PEMFCs. Also outstanding is that the flexible PEMFC retains 89.1% of its original performance after being bent 600 times, and it retains its original performance after being dropped five times from a height of 30 m. Moreover, the research has demonstrated that when stacked, the flexible PEMFCs are also useful in mobile applications such as mobile phones. Therefore, our research shows that PEMFCs can be made light, flexible, and suitable for applications in flexible devices. These innovative flexible PEMFCs may also notably advance the progress in the PEMFC field, because flexible PEMFCs can achieve high specific power density with small size, small volume, low weight, and much lower cost; they are also much easier to mass produce.

  19. Anti-Ferroelectric Ceramics for High Energy Density Capacitors

    Directory of Open Access Journals (Sweden)

    Aditya Chauhan

    2015-11-01

    Full Text Available With an ever increasing dependence on electrical energy for powering modern equipment and electronics, research is focused on the development of efficient methods for the generation, storage and distribution of electrical power. In this regard, the development of suitable dielectric based solid-state capacitors will play a key role in revolutionizing modern day electronic and electrical devices. Among the popular dielectric materials, anti-ferroelectrics (AFE display evidence of being a strong contender for future ceramic capacitors. AFE materials possess low dielectric loss, low coercive field, low remnant polarization, high energy density, high material efficiency, and fast discharge rates; all of these characteristics makes AFE materials a lucrative research direction. However, despite the evident advantages, there have only been limited attempts to develop this area. This article attempts to provide a focus to this area by presenting a timely review on the topic, on the relevant scientific advancements that have been made with respect to utilization and development of anti-ferroelectric materials for electric energy storage applications. The article begins with a general introduction discussing the need for high energy density capacitors, the present solutions being used to address this problem, and a brief discussion of various advantages of anti-ferroelectric materials for high energy storage applications. This is followed by a general description of anti-ferroelectricity and important anti-ferroelectric materials. The remainder of the paper is divided into two subsections, the first of which presents various physical routes for enhancing the energy storage density while the latter section describes chemical routes for enhanced storage density. This is followed by conclusions and future prospects and challenges which need to be addressed in this particular field.

  20. A Study on the Response Characteristics of a Fiber-Optic Radiation Sensor Model Based on Cerenkov Principle

    Energy Technology Data Exchange (ETDEWEB)

    Han, Hwa Jeong; Kim, Beom Kyu; Park, Byung Gi [Soonchunhyang Univ., Asan (Korea, Republic of)

    2016-10-15

    In recent year, various fiber-optic radiation sensors using Cerenkov principle have been developed without employing any scintillators for measuring high-energy photon, electron, etc. The main advantages of the optical fibers are the remote transmission of the light signal and immunity to pressure and electromagnetic waves. Therefore, the sensors utilizing the optical fibers can be used in hazardous radiation environments, such as the high-level radiation areas of a nuclear facility. The study to be simulated a fiber-optic radiation sensor based on Cerenkov principle and to be analyzed the response characteristics of the sensor. For the aforementioned study, the GEANT simulation toolkit was used. It is able to take into all the optical properties of fibers and is found to be appropriate to realistically describe the response of fiber-optic radiation sensor. In the recently, the fiber-optic radiation sensor have been developed in nuclear industry. Because sensor can detect gamma ray in harsh nuclear environments. In this study, we analyzed response characteristics of the fiber-optic radiation sensor. We have simulated the Monte Carlo model, for detecting the Cerenkov radiation using the fiber-optic radiation sensor. And the y-axis distribution of Cerenkov photons was obtained using output file. Simulation is performed with reference to the method of the previous research, and then the simulation results exhibited a good agreement with the previous research.

  1. Field trial of composite fiber-optic overhead ground wire

    Science.gov (United States)

    Kubota, S.; Kawahira, H.; Nakajima, T.; Matsubara, I.; Saito, Y.; Kitayama, Y.

    A composite fiber-optic ground wire (OPGW), which provides additional communication capabilities for system protection and control of overhead power transmission systems has been developed. After laboratory tests, the OPGW was strung along a live power transmission line in a mountainous region and has been confirmed to have sufficient performance to establish a high-speed digital transmission network able to withstand actual conditions. The field line, constructed substantially by existing techniques, has proved that the new OPGW, accessories such as clamps and joint boxes, installation technique, and on-tower splicing method can be effectively utilized to produce a protection and control system with extremely stable characteristics.

  2. Nanostructured thin solid oxide fuel cells with high power density.

    Science.gov (United States)

    Ignatiev, Alex; Chen, Xin; Wu, Naijuan; Lu, Zigui; Smith, Laverne

    2008-10-28

    Nanostructured thin film solid oxide fuel cells (SOFC) have been developed for reduced temperature operation, with high power density, and to be self reforming. A thin film electrolyte (1-2 microm thickness), e.g., yttria-stabilized zirconia (YSZ), is deposited on a nickel foil substrate. The electrolyte thin film is polycrystalline when deposited on a polycrystalline nickel foil substrate, and is (100) textured when deposited on an atomically textured nickel foil substrate. The Ni foil substrate is then converted into a porous SOFC anode by photolithographic patterning and etching to develop porosity. A composite La(0.5)Sr(0.5)CoO(3) cathode is then deposited on the thin film electrolyte. The resultant thin film hetero structure fuel cells have operated at a significantly reduced temperature: as low as 470 degrees C, with a maximum power density of 140 mW cm(-2) at 575 degrees C, and an efficiency of >50%. This drastic reduction in operating temperature for an SOFC now also allows for the use of hydrocarbon fuels without the need for a separate reformer as the nickel anode effectively dissociates hydrocarbons within this temperature range. These nanostructured fuel cells show excellent potential for high power density, small volume, high efficiency fuel cells for power generation applications.

  3. High Energy Density Physics and Exotic Acceleration Schemes

    Energy Technology Data Exchange (ETDEWEB)

    Cowan, T.; /General Atomics, San Diego; Colby, E.; /SLAC

    2005-09-27

    The High Energy Density and Exotic Acceleration working group took as our goal to reach beyond the community of plasma accelerator research with its applications to high energy physics, to promote exchange with other disciplines which are challenged by related and demanding beam physics issues. The scope of the group was to cover particle acceleration and beam transport that, unlike other groups at AAC, are not mediated by plasmas or by electromagnetic structures. At this Workshop, we saw an impressive advancement from years past in the area of Vacuum Acceleration, for example with the LEAP experiment at Stanford. And we saw an influx of exciting new beam physics topics involving particle propagation inside of solid-density plasmas or at extremely high charge density, particularly in the areas of laser acceleration of ions, and extreme beams for fusion energy research, including Heavy-ion Inertial Fusion beam physics. One example of the importance and extreme nature of beam physics in HED research is the requirement in the Fast Ignitor scheme of inertial fusion to heat a compressed DT fusion pellet to keV temperatures by injection of laser-driven electron or ion beams of giga-Amp current. Even in modest experiments presently being performed on the laser-acceleration of ions from solids, mega-amp currents of MeV electrons must be transported through solid foils, requiring almost complete return current neutralization, and giving rise to a wide variety of beam-plasma instabilities. As keynote talks our group promoted Ion Acceleration (plenary talk by A. MacKinnon), which historically has grown out of inertial fusion research, and HIF Accelerator Research (invited talk by A. Friedman), which will require impressive advancements in space-charge-limited ion beam physics and in understanding the generation and transport of neutralized ion beams. A unifying aspect of High Energy Density applications was the physics of particle beams inside of solids, which is proving to

  4. Standing waves in fiber-optic interferometers

    NARCIS (Netherlands)

    De Haan, V.; Santbergen, R.; Tijssen, M.; Zeman, M.

    2011-01-01

    A study is presented giving the response of three types of fiber-optic interferometers by which a standing wave through an object is investigated. The three types are a Sagnac, Mach–Zehnder and Michelson–Morley interferometer. The response of the Mach–Zehnder interferometer is similar to the Sagnac

  5. Overview of Fiber-Optical Sensors

    Science.gov (United States)

    Depaula, Ramon P.; Moore, Emery L.

    1987-01-01

    Design, development, and sensitivity of sensors using fiber optics reviewed. State-of-the-art and probable future developments of sensors using fiber optics described in report including references to work in field. Serves to update previously published surveys. Systems incorporating fiber-optic sensors used in medical diagnosis, navigation, robotics, sonar, power industry, and industrial controls.

  6. High energy density Z-pinch plasmas using flow stabilization

    Energy Technology Data Exchange (ETDEWEB)

    Shumlak, U., E-mail: shumlak@uw.edu; Golingo, R. P., E-mail: shumlak@uw.edu; Nelson, B. A., E-mail: shumlak@uw.edu; Bowers, C. A., E-mail: shumlak@uw.edu; Doty, S. A., E-mail: shumlak@uw.edu; Forbes, E. G., E-mail: shumlak@uw.edu; Hughes, M. C., E-mail: shumlak@uw.edu; Kim, B., E-mail: shumlak@uw.edu; Knecht, S. D., E-mail: shumlak@uw.edu; Lambert, K. K., E-mail: shumlak@uw.edu; Lowrie, W., E-mail: shumlak@uw.edu; Ross, M. P., E-mail: shumlak@uw.edu; Weed, J. R., E-mail: shumlak@uw.edu [Aerospace and Energetics Research Program, University of Washington, Seattle, Washington, 98195-2250 (United States)

    2014-12-15

    The ZaP Flow Z-Pinch research project[1] at the University of Washington investigates the effect of sheared flows on MHD instabilities. Axially flowing Z-pinch plasmas are produced that are 100 cm long with a 1 cm radius. The plasma remains quiescent for many radial Alfvén times and axial flow times. The quiescent periods are characterized by low magnetic mode activity measured at several locations along the plasma column and by stationary visible plasma emission. Plasma evolution is modeled with high-resolution simulation codes – Mach2, WARPX, NIMROD, and HiFi. Plasma flow profiles are experimentally measured with a multi-chord ion Doppler spectrometer. A sheared flow profile is observed to be coincident with the quiescent period, and is consistent with classical plasma viscosity. Equilibrium is determined by diagnostic measurements: interferometry for density; spectroscopy for ion temperature, plasma flow, and density[2]; Thomson scattering for electron temperature; Zeeman splitting for internal magnetic field measurements[3]; and fast framing photography for global structure. Wall stabilization has been investigated computationally and experimentally by removing 70% of the surrounding conducting wall to demonstrate no change in stability behavior.[4] Experimental evidence suggests that the plasma lifetime is only limited by plasma supply and current waveform. The flow Z-pinch concept provides an approach to achieve high energy density plasmas,[5] which are large, easy to diagnose, and persist for extended durations. A new experiment, ZaP-HD, has been built to investigate this approach by separating the flow Z-pinch formation from the radial compression using a triaxial-electrode configuration. This innovation allows more detailed investigations of the sheared flow stabilizing effect, and it allows compression to much higher densities than previously achieved on ZaP by reducing the linear density and increasing the pinch current. Experimental results and

  7. Hydrodynamic Instabilities in High-Energy-Density Settings

    Science.gov (United States)

    Smalyuk, Vladimir

    2016-10-01

    Our understanding of hydrodynamic instabilities, such as the Rayleigh-Taylor (RT), Richtmyer-Meshkov (RM), and Kelvin-Helmholtz (KH) instabilities, in high-energy-density (HED) settings over past two decades has progressed enormously. The range of conditions where hydrodynamic instabilities are experimentally observed now includes direct and indirect drive inertial confinement fusion (ICF) where surprises continue to emerge, linear and nonlinear regimes, classical interfaces vs. stabilized ablation fronts, tenuous ideal plasmas vs. high density Fermi degenerate plasmas, bulk fluid interpenetration vs. mixing down to the atomic level, in the presence of magnetic fields and/or intense radiation, and in solid state plastic flow at high pressures and strain rates. Regimes in ICF can involve extreme conditions of matter with temperatures up to kilovolts, densities of a thousand times solid densities, and time scales of nanoseconds. On the other hand, scaled conditions can be generated that map to exploding stars (supernovae) with length and time scales of millions of kilometers and hours to days or even years of instability evolution, planetary formation dynamics involving solid-state plastic flow which severely modifies the RT growth and continues to challenge reliable theoretical descriptions. This review will look broadly at progress in probing and understanding hydrodynamic instabilities in these very diverse HED settings, and then will examine a few cases in more depth to illustrate the detailed science involved. Experimental results on large-scale HED facilities such as the Omega, Nike, Gekko, and Shenguang lasers will be reviewed and the latest developments at the National Ignition Facility (NIF) and Z machine will be covered. Finally, current overarching questions and challenges will be summarized to motivate research directions for future. This work was performed under the auspices of the U.S. Department of Energy by LLNL under Contract DE-AC52-07NA27344.

  8. Aromatic Polyurea Possessing High Electrical Energy Density and Low Loss

    Science.gov (United States)

    Thakur, Yash; Lin, Minren; Wu, Shan; Zhang, Q. M.

    2016-10-01

    We report the development of a dielectric polymer, poly (ether methyl ether urea) (PEMEU), which possesses a dielectric constant of 4 and is thermally stable up to 150°C. The experimental results show that the ether units are effective in softening the rigid polymer and making it thermally processable, while the high dipole moment of urea units and glass structure of the polymer leads to a low dielectric loss and low conduction loss. As a result, PEMEU high quality thin films can be fabricated which exhibit exceptionally high breakdown field of >1.5 GV/m, and a low conduction loss at fields up to the breakdown. Consequently, the PEMEU films exhibit a high charge-discharge efficiency of 90% and a high discharged energy density of 36 J/cm3.

  9. High power density reactors based on direct cooled particle beds

    Science.gov (United States)

    Powell, J. R.; Horn, F. L.

    Reactors based on direct cooled High Temperature Gas Cooled Reactor (HTGR) type particle fuel are described. The small diameter particle fuel is packed between concentric porous cylinders to make annular fuel elements, with the inlet coolant gas flowing inwards. Hot exit gas flows out along the central channel of each element. Because of the very large heat transfer area in the packed beds, power densities in particle bed reactors (PBRs) are extremely high resulting in compact, lightweight systems. Coolant exit temperatures are high, because of the ceramic fuel temperature capabilities, and the reactors can be ramped to full power and temperature very rapidly. PBR systems can generate very high burst power levels using open cycle hydrogen coolant, or high continuous powers using closed cycle helium coolant. PBR technology is described and development requirements assessed.

  10. High-density cervical ureaplasma urealyticum colonization in pregnant women

    Directory of Open Access Journals (Sweden)

    Ranđelović Gordana

    2006-01-01

    Full Text Available Background/aim: Ureaplasma urealyticum, a common commensal of the female lower genital tract, has been observed as an important opportunistic pathogen during pregnancy. The aims of this study were to determine the degree of cervical colonization with U. urealyticum in pregnant women with risk pregnancy and in pregnant women with normal term delivery and to evaluate the correlation between high-density cervical U. urealyticum colonization and premature rupture of membranes (PROM as well. Methods. This research was conducted on the samples comprising 130 hospitalized pregnant women with threatening preterm delivery and premature rupture of membranes. The control group consisted of 39 pregnant women with term delivery without PROM. In addition to standard bacteriological examination and performing direct immunofluorescence test to detect Chlamydia trachomatis, cervical swabs were also examined for the presence of U. urealyticum and Mycoplasma hominis by commercially available Mycofast Evolution 2 test (International Microbio, France. Results. The number of findings with isolated high-density U. urealyticum in the target group was 69 (53.08%, while in the control group was 14 (35.90%. Premature rupture of membranes (PROM occurred in 43 (33.08% examinees: 29 were pPROM, and 14 were PROM. The finding of U.urealyticum ≥104 was determined in 25 (58.14% pregnant women with rupture, 17 were pPROM, and 8 were PROM. There was statistically significant difference in the finding of high-density U. urealyticum between the pregnant women with PROM and the control group (χ² = 4.06, p < 0.05. U. urealyticum was predominant bacterial species found in 62.79% of isolates in the PROM cases, while in 32.56% it was isolated alone. Among the 49 pregnant women with preterm delivery, pPROM occurred in 29 (59.18% examinees, and in 70.83% of pregnant women with findings of high-density U. urealyticum pPROM was observed. Conclusion. Cervical colonization with U

  11. High Density Thermal Energy Storage with Supercritical Fluids

    Science.gov (United States)

    Ganapathi, Gani B.; Wirz, Richard

    2012-01-01

    A novel approach to storing thermal energy with supercritical fluids is being investigated, which if successful, promises to transform the way thermal energy is captured and utilized. The use of supercritical fluids allows cost-affordable high-density storage with a combination of latent heat and sensible heat in the two-phase as well as the supercritical state. This technology will enhance penetration of several thermal power generation applications and high temperature water for commercial use if the overall cost of the technology can be demonstrated to be lower than the current state-of-the-art molten salt using sodium nitrate and potassium nitrate eutectic mixtures.

  12. Areal density optimizations for heat-assisted magnetic recording of high-density media

    Science.gov (United States)

    Vogler, Christoph; Abert, Claas; Bruckner, Florian; Suess, Dieter; Praetorius, Dirk

    2016-06-01

    Heat-assisted magnetic recording (HAMR) is hoped to be the future recording technique for high-density storage devices. Nevertheless, there exist several realization strategies. With a coarse-grained Landau-Lifshitz-Bloch model, we investigate in detail the benefits and disadvantages of a continuous and pulsed laser spot recording of shingled and conventional bit-patterned media. Additionally, we compare single-phase grains and bits having a bilayer structure with graded Curie temperature, consisting of a hard magnetic layer with high TC and a soft magnetic one with low TC, respectively. To describe the whole write process as realistically as possible, a distribution of the grain sizes and Curie temperatures, a displacement jitter of the head, and the bit positions are considered. For all these cases, we calculate bit error rates of various grain patterns, temperatures, and write head positions to optimize the achievable areal storage density. Within our analysis, shingled HAMR with a continuous laser pulse moving over the medium reaches the best results and thus has the highest potential to become the next-generation storage device.

  13. Path to Efficient Lower Hybrid Current Drive at High Density

    Science.gov (United States)

    Baek, S. G.; Bonoli, P. T.; Brunner, D.; Faust, I.; Labombard, B. L.; Parker, R. R.; Shiraiwa, S.; Wallace, G. M.; Wukitch, S.

    2015-11-01

    Recovery of lower hybrid current drive (LHCD) efficiency at high density was demonstrated on Alcator C-Mod by modifying the scrape-off layer (SOL) plasma. RF probe measurements around the C-Mod tokamak indicate that the LH wave amplitude at the high field side wall significantly attenuates with plasma density. This is interpreted as enhanced collisional loss due to the increase in the SOL density and width. By taking advantage of the narrower SOL width by doubling plasma current to 1.1 MA, it is found that the LH wave amplitude maintains its strength, and an effective current drive is extended to above 1x10e20 m-3. An order of magnitude increase in non-thermal Bremsstrahlung emission is consistent with ray-tracing results which take into account the change of SOL profiles with current. In the coming campaign, a further investigation on the role of the SOL plasma is planned by raising plasma current above 1.1 MA. This will be aided with newly developed RF magnetic loop antennas mounted on a radially movable probe head. This system is expected to intercept the LH resonance cone on the first pass, allowing us to measure radial profiles of both the wave amplitude and dominant parallel wavenumber in the SOL for the first time. These data will be compared with the GENRAY ray-tracing code. Work supported by USDoE awards DE-FC02-99ER54512.

  14. Patterned Platinum Etching Studies in an Argon High Density Plasma

    Science.gov (United States)

    Delprat, Sébastien; Chaker, Mohamed; Margot, Joëlle; Pépin, Henri; Tan, Liang; Smy, Tom

    1998-10-01

    A high-density surface-wave Ar plasma operated in the low pressure regime is used to study pure physical etching characteristics of platinum thin films. The platinum samples are RF biased so as to obtain a maximum DC self-bias voltage of 150 V. The sputter-etching characteristics are investigated as a function of the magnetic field intensity, the self-bias voltage and the gas pressure. At 1 mtorr, the etch rate is found to be a unique linear function of both the self-bias voltage and the ion density, independently of the magnetic field intensity value. However, even though the ion density increases, the etch rate is found to decrease with increasing pressure. In the low pressure regime, etch rates as high as 2000 A/min are obtained with a good selectivity over resist. Without any optimization of the etching process, we were able to etch 0.5 micron Pt trenches, 0.6 micron thick yielding fence-free profiles and sidewall angles (75º) that already meets the present industrial requirements of NVRAM technology.

  15. High Power Density Power Electronic Converters for Large Wind Turbines

    DEFF Research Database (Denmark)

    Senturk, Osman Selcuk

    In large wind turbines (in MW and multi-MW ranges), which are extensively utilized in wind power plants, full-scale medium voltage (MV) multi-level (ML) voltage source converters (VSCs) are being more preferably employed nowadays for interfacing these wind turbines with electricity grids...... assessments of these specific VSCs so that their power densities and reliabilities are quantitatively determined, which requires extensive utilization of the electro-thermal models of the VSCs under investigation. In this thesis, the three-level neutral-point-clamped VSCs (3L-NPC-VSCs), which are classified......-HB-VSCs). As the switch technology for realizing these 3L-VSCs, press-pack IGBTs are chosen to ensure high power density and reliability. Based on the selected 3L-VSCs and switch technology, the converter electro-thermal models are developed comprehensively, implemented practically, and validated via a full-scale 3L...

  16. Microelectromechanical high-density energy storage/rapid release system

    Science.gov (United States)

    Rodgers, M. Steven; Allen, James J.; Meeks, Kent D.; Jensen, Brian D.; Miller, Samuel L.

    1999-08-01

    One highly desirable characteristic of electrostatically driven microelectromechanical systems (MEMS) is that they consume very little power. The corresponding drawback is that the force they produce may be inadequate for many applications. It has previously been demonstrated that gear reduction units or microtransmissions can substantially increase the torque generated by microengines. Operating speed, however, is also reduced by the transmission gear ratio. Some applications require both high speed and high force. If this output is only required for a limited period of time, then energy could be stored in a mechanical system and rapidly released upon demand. We have designed, fabricated, and demonstrated a high-density energy storage/rapid release system that accomplishes this task. Built using a 5-level surface micromachining technology, the assembly closely resembles a medieval crossbow. Energy releases on the order of tens of nanojoules have already been demonstrated, and significantly higher energy systems are under development.

  17. Toward Low-Cost, High-Energy Density, and High-Power Density Lithium-Ion Batteries

    Science.gov (United States)

    Li, Jianlin; Du, Zhijia; Ruther, Rose E.; AN, Seong Jin; David, Lamuel Abraham; Hays, Kevin; Wood, Marissa; Phillip, Nathan D.; Sheng, Yangping; Mao, Chengyu; Kalnaus, Sergiy; Daniel, Claus; Wood, David L.

    2017-06-01

    Reducing cost and increasing energy density are two barriers for widespread application of lithium-ion batteries in electric vehicles. Although the cost of electric vehicle batteries has been reduced by 70% from 2008 to 2015, the current battery pack cost (268/kWh in 2015) is still >2 times what the USABC targets (125/kWh). Even though many advancements in cell chemistry have been realized since the lithium-ion battery was first commercialized in 1991, few major breakthroughs have occurred in the past decade. Therefore, future cost reduction will rely on cell manufacturing and broader market acceptance. This article discusses three major aspects for cost reduction: (1) quality control to minimize scrap rate in cell manufacturing; (2) novel electrode processing and engineering to reduce processing cost and increase energy density and throughputs; and (3) material development and optimization for lithium-ion batteries with high-energy density. Insights on increasing energy and power densities of lithium-ion batteries are also addressed.

  18. Toward Low-Cost, High-Energy Density, and High-Power Density Lithium-Ion Batteries

    Science.gov (United States)

    Li, Jianlin; Du, Zhijia; Ruther, Rose E.; AN, Seong Jin; David, Lamuel Abraham; Hays, Kevin; Wood, Marissa; Phillip, Nathan D.; Sheng, Yangping; Mao, Chengyu; Kalnaus, Sergiy; Daniel, Claus; Wood, David L.

    2017-09-01

    Reducing cost and increasing energy density are two barriers for widespread application of lithium-ion batteries in electric vehicles. Although the cost of electric vehicle batteries has been reduced by 70% from 2008 to 2015, the current battery pack cost (268/kWh in 2015) is still >2 times what the USABC targets (125/kWh). Even though many advancements in cell chemistry have been realized since the lithium-ion battery was first commercialized in 1991, few major breakthroughs have occurred in the past decade. Therefore, future cost reduction will rely on cell manufacturing and broader market acceptance. This article discusses three major aspects for cost reduction: (1) quality control to minimize scrap rate in cell manufacturing; (2) novel electrode processing and engineering to reduce processing cost and increase energy density and throughputs; and (3) material development and optimization for lithium-ion batteries with high-energy density. Insights on increasing energy and power densities of lithium-ion batteries are also addressed.

  19. Multifractal analysis of high resolution solar wind proton density measurements

    Science.gov (United States)

    Sorriso-Valvo, Luca; Carbone, Francesco; Leonardis, Ersilia; Chen, Christopher H. K.; Šafránková, Jana; Němeček, Zdenek

    2017-03-01

    The solar wind is a highly turbulent medium, with a high level of field fluctuations throughout a broad range of scales. These include an inertial range where a turbulent cascade is assumed to be active. The solar wind cascade shows intermittency, which however may depend on the wind conditions. Recent observations have shown that ion-scale magnetic turbulence is almost self-similar, rather than intermittent. A similar result was observed for the high resolution measurements of proton density provided by the spacecraft Spektr-R. Intermittency may be interpreted as the result of the multifractal properties of the turbulent cascade. In this perspective, this paper is devoted to the description of the multifractal properties of the high resolution density measurements. In particular, we have used the standard coarse-graining technique to evaluate the generalized dimensions Dq , and from these the multifractal spectrum f (α) , in two ranges of scale. A fit with the p-model for intermittency provided a quantitative measure of multifractality. Such indicator was then compared with alternative measures: the width of the multifractal spectrum, the peak of the kurtosis, and its scaling exponent. The results indicate that the small-scale fluctuations are multifractal, and suggest that different measures of intermittency are required to fully understand the small scale cascade.

  20. Ultra-Stretchable Interconnects for High-Density Stretchable Electronics

    Directory of Open Access Journals (Sweden)

    Salman Shafqat

    2017-09-01

    Full Text Available The exciting field of stretchable electronics (SE promises numerous novel applications, particularly in-body and medical diagnostics devices. However, future advanced SE miniature devices will require high-density, extremely stretchable interconnects with micron-scale footprints, which calls for proven standardized (complementary metal-oxide semiconductor (CMOS-type process recipes using bulk integrated circuit (IC microfabrication tools and fine-pitch photolithography patterning. Here, we address this combined challenge of microfabrication with extreme stretchability for high-density SE devices by introducing CMOS-enabled, free-standing, miniaturized interconnect structures that fully exploit their 3D kinematic freedom through an interplay of buckling, torsion, and bending to maximize stretchability. Integration with standard CMOS-type batch processing is assured by utilizing the Flex-to-Rigid (F2R post-processing technology to make the back-end-of-line interconnect structures free-standing, thus enabling the routine microfabrication of highly-stretchable interconnects. The performance and reproducibility of these free-standing structures is promising: an elastic stretch beyond 2000% and ultimate (plastic stretch beyond 3000%, with <0.3% resistance change, and >10 million cycles at 1000% stretch with <1% resistance change. This generic technology provides a new route to exciting highly-stretchable miniature devices.

  1. Pistachio intake increases high density lipoprotein levels and inhibits low-density lipoprotein oxidation in rats.

    Science.gov (United States)

    Aksoy, Nur; Aksoy, Mehmet; Bagci, Cahit; Gergerlioglu, H Serdar; Celik, Hakim; Herken, Emine; Yaman, Abdullah; Tarakcioglu, Mehmet; Soydinc, Serdar; Sari, Ibrahim; Davutoglu, Vedat

    2007-05-01

    There is increasing evidence that nuts have protective effects against coronary artery disease by improving lipid profile and inhibiting lipid oxidation. However, data about pistachio nuts are limited, and to our knowledge, there is no study investigating the effects of pistachio intake on lipid oxidation and serum antioxidant levels. This study, therefore, sought to determine the effects of pistachio intake on serum lipids and determine whether consumption of pistachio would alter serum antioxidant levels. Rats were randomly divided into three groups (n=12 for each): control group fed basic diet for 10 weeks and treated groups fed basic diet plus pistachio which constituted 20% and 40% of daily caloric intake, respectively. Consumption of pistachio as 20% of daily caloric intake increased high-density lipoprotein (HDL) levels and decreased total cholesterol (TC)/HDL ratio, compared with those not taking pistachio. However, TC, low-density lipoprotein (LDL) cholesterol and triglyceride levels were unaffected by pistachio consumption. Consumption of pistachio as 20% of daily caloric intake increased serum paraoxonase activity by 35% and arylesterase activity by 60%, which are known to inhibit LDL cholesterol oxidation, compared with the control group. However, increased antioxidant activity was blunted when pistachio intake was increased to 40% of daily caloric intake. In conclusion, the present results show that consumption of pistachio as 20% of daily caloric intake leads to significant improvement in HDL and TC/HDL ratio and inhibits LDL cholesterol oxidation. These results suggest that pistachio may be beneficial for both prevention and treatment of coronary artery disease.

  2. High energy density capacitors using nano-structure multilayer technology

    Energy Technology Data Exchange (ETDEWEB)

    Barbee, T.W. Jr.; Johnson, G.W.; O`Brien, D.W.

    1992-08-01

    Today, many pulse power and industrial applications are limited by capacitor performance. While incremental improvements are anticipated from existing capacitor technologies, significant advances are needed in energy density to enable these applications for both the military and for American economic competitiveness. We propose a program to research and develop a novel technology for making high voltage, high energy density capacitors. Nano-structure multilayer technologies developed at LLNL may well provide a breakthrough in capacitor performance. Our controlled sputtering techniques are capable of laying down extraordinarily smooth sub-micron layers of dielectric and conductor materials. With this technology, high voltage capacitors with an order of magnitude improvement in energy density may be achievable. Well-understood dielectrics and new materials will be investigated for use with this technology. Capacitors developed by nano-structure multilayer technology are inherently solid state, exhibiting extraordinary mechanical and thermal properties. The conceptual design of a Notepad capacitor is discussed to illustrate capacitor and capacitor bank design and performance with this technology. We propose a two phase R&D program to address DNA`s capacitor needs for electro-thermal propulsion and similar pulse power programs. Phase 1 will prove the concept and further our understanding of dielectric materials and design tradeoffs with multilayers. Nano-structure multilayer capacitors will be developed and characterized. As our materials research and modeling prove successful, technology insertion in our capacitor designs will improve the possibility for dramatic performance improvements. In Phase 2, we will make Notepad capacitors, construct a capacitor bank and demonstrate its performance in a meaningful pulse power application. We will work with industrial partners to design full scale manufacturing and move this technology to industry for volume production.

  3. The Pulsed High Density Experiment (PHDX) Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Slough, John P. [Univ. of Washington, Seattle, WA (United States); Andreason, Samuel [Univ. of Washington, Seattle, WA (United States)

    2017-04-27

    The purpose of this paper is to present the conclusions that can be drawn from the Field Reversed Configuration (FRC) formation experiments conducted on the Pulsed High Density experiment (PHD) at the University of Washington. The experiment is ongoing. The experimental goal for this first stage of PHD was to generate a stable, high flux (>10 mWb), high energy (>10 KJ) target FRC. Such results would be adequate as a starting point for several later experiments. This work focuses on experimental implementation and the results of the first four month run. Difficulties were encountered due to the initial on-axis plasma ionization source. Flux trapping with this ionization source acting alone was insufficient to accomplish experimental objectives. Additional ionization methods were utilized to overcome this difficulty. A more ideal plasma source layout is suggested and will be explored during a forthcoming work.

  4. [Residual risk: The roles of triglycerides and high density lipoproteins].

    Science.gov (United States)

    Grammer, Tanja; Kleber, Marcus; Silbernagel, Günther; Scharnagl, Hubert; März, Winfried

    2016-06-01

    In clinical trials, the reduction of LDL-cholesterol (LDL-C) with statins reduces the incidence rate of cardiovascular events by approximately one third. This means, that a sizeable "residual risk" remains. Besides high lipoprotein (a), disorders in the metabolism of triglyceride-rich lipoproteins and high density liproteins have been implicated as effectors of the residual risk. Both lipoprotein parameters correlate inversely with each other. Therefore, the etiological contributions of triglycerides and / or of HDL for developing cardiovascular disease can hardly be estimated from either observational studies or from intervention studies. The largely disappointing results of intervention studies with inhibitors of the cholesteryl ester transfer protein and in particular the available set of genetically-epidemiological studies suggest that in the last decade, the importance of HDL cholesterol has been overvalued, while the importance of triglycerides has been underestimated. High triglycerides not always atherogenic, but only if they are associated with the accumulation relatively cholesterol-enriched, incompletely catabolized remnants of chylomicrons and very low density lipoproteins (familial type III hyperlipidemia, metabolic syndrome, diabetes mellitus). The normalization of the concentration of triglycerides and remnants by inhibiting the expression of apolipoprotein C3 is hence a new, promising therapeutic target.

  5. Metal hydrides based high energy density thermal battery

    Energy Technology Data Exchange (ETDEWEB)

    Fang, Zhigang Zak, E-mail: zak.fang@utah.edu [Department of Metallurgical Engineering, The University of Utah, 135 South 1460 East, Room 412, Salt Lake City, UT 84112-0114 (United States); Zhou, Chengshang; Fan, Peng [Department of Metallurgical Engineering, The University of Utah, 135 South 1460 East, Room 412, Salt Lake City, UT 84112-0114 (United States); Udell, Kent S. [Department of Metallurgical Engineering, The University of Utah, 50 S. Central Campus Dr., Room 2110, Salt Lake City, UT 84112-0114 (United States); Bowman, Robert C. [Department of Metallurgical Engineering, The University of Utah, 135 South 1460 East, Room 412, Salt Lake City, UT 84112-0114 (United States); Vajo, John J.; Purewal, Justin J. [HRL Laboratories, LLC, 3011 Malibu Canyon Road, Malibu, CA 90265 (United States); Kekelia, Bidzina [Department of Metallurgical Engineering, The University of Utah, 50 S. Central Campus Dr., Room 2110, Salt Lake City, UT 84112-0114 (United States)

    2015-10-05

    Highlights: • The principle of the thermal battery using advanced metal hydrides was demonstrated. • The thermal battery used MgH{sub 2} and TiMnV as a working pair. • High energy density can be achieved by the use of MgH{sub 2} to store thermal energy. - Abstract: A concept of thermal battery based on advanced metal hydrides was studied for heating and cooling of cabins in electric vehicles. The system utilized a pair of thermodynamically matched metal hydrides as energy storage media. The pair of hydrides that was identified and developed was: (1) catalyzed MgH{sub 2} as the high temperature hydride material, due to its high energy density and enhanced kinetics; and (2) TiV{sub 0.62}Mn{sub 1.5} alloy as the matching low temperature hydride. Further, a proof-of-concept prototype was built and tested, demonstrating the potential of the system as HVAC for transportation vehicles.

  6. Multi-targeting single fiber-optic biosensor based on evanescent wave and quantum dots

    NARCIS (Netherlands)

    Zhang, Y.; Zeng, Q.; Sun, Y.; Liu, X.; Tu, L.; Kong, X.; Buma, W.J.; Zhang, H.

    2010-01-01

    Highly sensitive, multi-analyte assay is a long-standing challenge for a single fiber-optic evanescent wave biosensor (FOB). In this paper, we report the first realization of such kind of FOB using CdSe/ZnS core/shell quantum dots (QDs) as labels. A direct binding assay model between antibody and an

  7. A New Hard Switching Bidirectional Converter With High Power Density

    Directory of Open Access Journals (Sweden)

    Bahador Fani

    2010-01-01

    Full Text Available In this paper, a new isolated dc-dc bidirectional converter is proposed. This converter consists of two transformers (flyback and forward and only one switch in primary side and one switch in secondary side of transformers. In this converter energy transfers to the output in both on and off switch states so power density of this converter is high This converter controlled by PWM signal. Also this converter operates over a wide input voltage range. Theoretical analysis is presented and computer simulation and experimental results verify the converter analysis.

  8. On high-order perturbative calculations at finite density

    CERN Document Server

    Ghisoiu, Ioan

    2017-01-01

    We discuss the prospects of performing high-order perturbative calculations in systems characterized by a vanishing temperature but finite density. In particular, we show that the determination of generic Feynman integrals containing fermionic chemical potentials can be reduced to the evaluation of three-dimensional phase space integrals over vacuum on-shell amplitudes. Applications of these rules will be discussed in the context of the thermodynamics of cold and dense QCD, where it is argued that they facilitate an extension of the Equation of State of cold quark matter to higher perturbative orders.

  9. On high-order perturbative calculations at finite density

    Science.gov (United States)

    Ghişoiu, Ioan; Gorda, Tyler; Kurkela, Aleksi; Romatschke, Paul; Säppi, Matias; Vuorinen, Aleksi

    2017-02-01

    We discuss the prospects of performing high-order perturbative calculations in systems characterized by a vanishing temperature but finite density. In particular, we show that the determination of generic Feynman integrals containing fermionic chemical potentials can be reduced to the evaluation of three-dimensional phase space integrals over vacuum on-shell amplitudes - a result reminiscent of a previously proposed "naive real-time formalism" for vacuum diagrams. Applications of these rules are discussed in the context of the thermodynamics of cold and dense QCD, where it is argued that they facilitate an extension of the Equation of State of cold quark matter to higher perturbative orders.

  10. Ultra High Energy Density Cathodes with Carbon Nanotubes

    Science.gov (United States)

    2013-12-10

    34Enhanced Capacity and Rate Capability of Carbon Nanotube Based Anodes with Titanium Contacts for Lithium Ion Batteries," ACS Nano, vol. 4, pp. 6121- 6131...2010/10/26 2010. [2] S. L. Chou, et al., "Silicon/Single-Walled Carbon Nanotube Composite Paper as a Flexible Anode Material for Lithium Ion...AFRL-RV-PS- AFRL-RV-PS- TR-2013-0170 TR-2013-0170 ULTRA HIGH ENERGY DENSITY CATHODES WITH CARBON NANOTUBES Brian J. Landi, et al. Rochester

  11. High density QCD and entropy production at heavy ion colliders

    CERN Document Server

    Kinder-Geiger, Klaus

    1994-01-01

    The role of entropy production in the context of probing QCD properties at high densities and finite temperatures in ultra-relativistic collisions of heavy nuclei is inspected. It is argued that the entropy generated in these reactions provides a powerful tool to investigate the space-time evolution and the question whether and how a deconfined plasma of quarks and gluons is formed. I will address the questions how entropy is produced, and how it is measurable. The uncertainties in predicting the different contributions to the total entropy and particle multiplicities during the course of heavy ion collisions are also discussed.

  12. Method for providing a low density high strength polyurethane foam

    Science.gov (United States)

    Whinnery, Jr., Leroy L.; Goods, Steven H.; Skala, Dawn M.; Henderson, Craig C.; Keifer, Patrick N.

    2013-06-18

    Disclosed is a method for making a polyurethane closed-cell foam material exhibiting a bulk density below 4 lbs/ft.sup.3 and high strength. The present embodiment uses the reaction product of a modified MDI and a sucrose/glycerine based polyether polyol resin wherein a small measured quantity of the polyol resin is "pre-reacted" with a larger quantity of the isocyanate in a defined ratio such that when the necessary remaining quantity of the polyol resin is added to the "pre-reacted" resin together with a tertiary amine catalyst and water as a blowing agent, the polymerization proceeds slowly enough to provide a stable foam body.

  13. The physics of ultra-high-density magnetic recording

    CERN Document Server

    Ek, Johannes; Weller, Dieter

    2001-01-01

    In this book, 17 experts in magnetic recording focus on the underlying physical mechanisms that play crucial roles in medium and transducer development for high areal density disk drives. In 11 chapters, an examination is made of the fundamental physical concepts and their impact on recording mechanisms, with special emphasis on thin-film longitudinal, perpendicular, patterned and nanoparticle media. Theoretical and experimental investigations are presented which serve to enhance our basic understanding of thin-film dynamics, medium dynamics and thermal effects. Fundamental aspects of magnetotransport are discussed and an overview is given of recording head designs.

  14. Antarctic marine gravity field from high-density satellite altimetry

    Science.gov (United States)

    Sandwell, David T.

    1992-01-01

    High-density (about 2-km profile spacing) Geosat/GM altimetry profiles were obtained for Antarctic waters (6-deg S to 72 deg S) and converted to vertical gravity gradient, using Laplace's equation to directly calculate gravity gradient from vertical deflection grids and Fourier analysis to construct gravity anomalies from two vertical deflection grids. The resultant gravity grids have resolution and accuracy comparable to shipboard gravity profiles. The obtained gravity maps display many interesting and previously uncharted features, such as a propagating rift wake and a large 'leaky transform' along the Pacific-Antarctic Rise.

  15. A Cherenkov Radiation Detector with High Density Aerogels

    CERN Document Server

    Cremaldi, Lucien; Sonnek, Peter; Summers, Donald J; Reidy, Jim

    2009-01-01

    We have designed a threshold Cherenkov detector at the Rutherford-Appleton Laboratory to identify muons with momenta between 230 and 350 MeV/c. We investigated the properties of three aerogels for the design. The nominal indexes of refraction were n = 1.03, 1.07, 1.12, respectively. Two of the samples are of high density aerogel not commonly used for Cherenkov light detection. We present results of an examination of some optical properties of the aerogel samples and present basic test beam results.

  16. Biomimetic High Density Lipoprotein Nanoparticles For Nucleic Acid Delivery

    Science.gov (United States)

    McMahon, Kaylin M.; Mutharasan, R. Kannan; Tripathy, Sushant; Veliceasa, Dorina; Bobeica, Mariana; Shumaker, Dale K.; Luthi, Andrea J.; Helfand, Brian T.; Ardehali, Hossein; Mirkin, Chad A.; Volpert, Olga; Thaxton, C. Shad

    2014-01-01

    We report a gold nanoparticle-templated high density lipoprotein (HDL AuNP) platform for gene therapy which combines lipid-based nucleic acid transfection strategies with HDL biomimicry. For proof-of-concept, HDL AuNPs are shown to adsorb antisense cholesterylated DNA. The conjugates are internalized by human cells, can be tracked within cells using transmission electron microscopy (TEM), and regulate target gene expression. Overall, the ability to directly image the AuNP core within cells, the chemical tailorability of the HDL AuNP platform, and the potential for cell-specific targeting afforded by HDL biomimicry make this platform appealing for nucleic acid delivery. PMID:21319839

  17. Wide-Dynamic-Range Cantilever Magnetometry Using a Fiber-Optic Interferometer and its Application to High-frequency Electron Spin Resonance Spectroscopy

    CERN Document Server

    Takahashi, Hideyuki; Ohmichi, Eiji; Ohta, Hitoshi

    2016-01-01

    We present a method of broadening the dynamic range of optical interferometric detection of cantilever displacement. The key idea of this system is to use a wavelength-tunable laser source. The wavelength is subject to proportional-integral control, which is used to keep the cavity detuning constant during a measurement. Under this control, the change in wavelength is proportional to the cantilever displacement. Using this technique, we can measure large displacements ($>1\\ \\mathrm{\\mu m}$) without degradation of sensitivity. We apply this technique to high-frequency electron spin resonance spectroscopy and succeed in removing an irregular background signal that arises from the constantly varying sensitivity of the interferometer.

  18. Wide-dynamic-range cantilever magnetometry using a fiber-optic interferometer and its application to high-frequency electron spin resonance spectroscopy

    Science.gov (United States)

    Takahashi, Hideyuki; Okamoto, Tsubasa; Ohmichi, Eiji; Ohta, Hitoshi

    2016-12-01

    We present a method of broadening the dynamic range of optical interferometric detection of cantilever displacement. The key idea of this method is the use of a wavelength-tunable laser source. The wavelength is subject to proportional-integral control, which is used to keep the cavity detuning constant. Under this control, the change in wavelength is proportional to the cantilever displacement. Using this technique, we can measure large displacements (>1 µm) without degrading the sensitivity. We apply this technique to high-frequency electron spin resonance spectroscopy and succeed in removing an irregular background signal that arises from the constantly varying sensitivity of the interferometer.

  19. Computational imaging through a fiber-optic bundle

    Science.gov (United States)

    Lodhi, Muhammad A.; Dumas, John Paul; Pierce, Mark C.; Bajwa, Waheed U.

    2017-05-01

    Compressive sensing (CS) has proven to be a viable method for reconstructing high-resolution signals using low-resolution measurements. Integrating CS principles into an optical system allows for higher-resolution imaging using lower-resolution sensor arrays. In contrast to prior works on CS-based imaging, our focus in this paper is on imaging through fiber-optic bundles, in which manufacturing constraints limit individual fiber spacing to around 2 μm. This limitation essentially renders fiber-optic bundles as low-resolution sensors with relatively few resolvable points per unit area. These fiber bundles are often used in minimally invasive medical instruments for viewing tissue at macro and microscopic levels. While the compact nature and flexibility of fiber bundles allow for excellent tissue access in-vivo, imaging through fiber bundles does not provide the fine details of tissue features that is demanded in some medical situations. Our hypothesis is that adapting existing CS principles to fiber bundle-based optical systems will overcome the resolution limitation inherent in fiber-bundle imaging. In a previous paper we examined the practical challenges involved in implementing a highly parallel version of the single-pixel camera while focusing on synthetic objects. This paper extends the same architecture for fiber-bundle imaging under incoherent illumination and addresses some practical issues associated with imaging physical objects. Additionally, we model the optical non-idealities in the system to get lower modelling errors.

  20. Biominetic High Density Lipoproteins for the Delivery of Therapeutic Oligonucleotides

    Science.gov (United States)

    Tripathy, Sushant

    Advances in nanotechnology have brought about novel inorganic and hybrid nanoparticles with unique physico-chemical properties that make them suitable for a broad range of applications---from nano-circuitry to drug delivery. A significant part of those advancements have led to ground-breaking discoveries that have changed the approaches to formulation of therapeutics against diseases, such as cancer. Now-a-days the focus does not lie solely on finding a candidate small-molecule therapeutic with minimal adverse effects, but researchers are looking up to nanoparticles to improve biodistribution and biocompatibility profile of clinically proven therapeutics. The plethora of conjugation chemistries offered by currently extant inorganic nanoparticles have, in recent years, led to great leaps in the field of biomimicry---a modality that promises high biocompatibility. Further, in the pursuit of highly specific therapeutic molecules, researchers have turned to silencing oligonucleotides and some have already brought together the strengths of nanoparticles and silencing oligonucleotides in search of an efficacious therapy for cancer with minimal adverse effects. This dissertation work focuses on such a biomimetic platform---a gold nanoparticle based high density lipoprotein biomimetic (HDL NP), for the delivery of therapeutic oligonucleotides. The first chapter of this body of work introduces the molecular target of the silencing oligonucleotides---VEGFR2, and its role in the progression of solid tumor cancers. The background information also covers important aspects of natural high density lipoproteins (HDL), especially their innate capacity to bind and deliver exogenous and endogenous silencing oligonucleotides to tissues that express their high affinity receptor SRB1. We subsequently describe the synthesis of the biomimetic HDL NP and its oligonucleotide conjugates, and establish their biocompatibility. Further on, experimental data demonstrate the efficacy of silencing

  1. Simulating deposition of high density tailings using smoothed particle hydrodynamics

    Science.gov (United States)

    Babaoglu, Yagmur; Simms, Paul H.

    2017-08-01

    Tailings are a slurry of silt-sized residual material derived from the milling of rock. High density (HD) tailings are tailings that have been sufficiently dewatered to a point where they exhibit a yield stress upon deposition. They form gently sloped stacks on the surface when deposited; this eliminates or minimizes the need for dams or embankments for containment. Understanding the flow behaviour of high density tailings is essential for estimating the final stack geometry and overall slope angle. This paper focuses on modelling the flow behaviour of HD tailings using smoothed particle hydrodynamics (SPH) method incorporating a `bi-viscosity' model to simulate the non-Newtonian behaviour. The model is validated by comparing the numerical results with bench scale experiments simulating single or multi-layer deposits in two-dimensions. The results indicate that the model agreed fairly well with the experimental work, excepting some repulsion of particles away from the bottom boundary closer to the toe of the deposits. Novel aspects of the work, compared to other simulation of Bingham fluids by SPH, are the simulation of multilayer deposits and the use of a stopping criteria to characterize the rest state.

  2. Multiple parton interactions in high-density QCD matter

    CERN Document Server

    Srivastava, D K; Srivastava, Dinesh K.; Geiger, Klaus

    1999-01-01

    Multiple interactions of quarks and gluons in high-energy heavy-ion collisions may give rise to interesting phemomena of color charges propagating in high-density QCD matter. We study the dynamics of multi-parton systems produced in nucleus-nucleus collisions at energies corresponding the the CERN SPS and the future BNL RHIC experiments. Due to the complexity of the multi-particle dynamics we choose to employ the parton cascade model in order to simulate the development of multiple parton scatterings and associated stimulated emision processes. Our results indicate a non-linear increase with nuclear mass A of, e.g., parton multiplicity, energy density, strangeness, and contrast a linear A-scaling as in Glauber-type approaches. If multiple interactions are suppressed and only single parton scatterings (no re-interactions) are considered, we recover such a linear behavior. It remains to be studied whether these results on the parton level can be experimentally seen in final-state observables, such as the charge...

  3. Development Status of High-Thrust Density Electrostatic Engines

    Science.gov (United States)

    Patterson, Michael J.; Haag, Thomas W.; Foster, John E.; Young, Jason A.; Crofton, Mark W.

    2017-01-01

    Ion thruster technology offers the highest performance and efficiency of any mature electric propulsion thruster. It has by far the highest demonstrated total impulse of any technology option, demonstrated at input power levels appropriate for primary propulsion. It has also been successfully implemented for primary propulsion in both geocentric and heliocentric environments, with excellent ground/in-space correlation of both its performance and life. Based on these attributes there is compelling reasoning to continue the development of this technology: it is a leading candidate for high power applications; and it provides risk reduction for as-yet unproven alternatives. As such it is important that the operational limitations of ion thruster technology be critically examined and in particular for its application to primary propulsion its capabilities relative to thrust the density and thrust-to-power ratio be understood. This publication briefly addresses some of the considerations relative to achieving high thrust density and maximizing thrust-to-power ratio with ion thruster technology, and discusses the status of development work in this area being executed under a collaborative effort among NASA Glenn Research Center, the Aerospace Corporation, and the University of Michigan.

  4. Strongly Interacting Matter at Very High Energy Density

    Energy Technology Data Exchange (ETDEWEB)

    McLerran, L.

    2011-06-05

    The authors discuss the study of matter at very high energy density. In particular: what are the scientific questions; what are the opportunities to makes significant progress in the study of such matter and what facilities are now or might be available in the future to answer the scientific questions? The theoretical and experimental study of new forms of high energy density matter is still very much a 'wild west' field. There is much freedom for developing new concepts which can have order one effects on the way we think about such matter. It is also a largely 'lawless' field, in that concepts and methods are being developed as new information is generated. There is also great possibility for new experimental discovery. Most of the exciting results from RHIC experiments were unanticipated. The methods used for studying various effects like flow, jet quenching, the ridge, two particle correlations etc. were developed as experiments evolved. I believe this will continue to be the case at LHC and as we use existing and proposed accelerators to turn theoretical conjecture into tangible reality. At some point this will no doubt evolve into a precision science, and that will make the field more respectable, but for my taste, the 'wild west' times are the most fun.

  5. High Energy Density Science at the Linac Coherent Light Source

    Energy Technology Data Exchange (ETDEWEB)

    Lee, R W

    2007-10-19

    High energy density science (HEDS), as a discipline that has developed in the United States from National Nuclear Security Agency (NNSA)-sponsored laboratory research programs, is, and will remain, a major component of the NNSA science and technology strategy. Its scientific borders are not restricted to NNSA. 'Frontiers in High Energy Density Physics: The X-Games of Contemporary Science' identified numerous exciting scientific opportunities in this field, while pointing to the need for a overarching interagency plan for its evolution. Meanwhile, construction of the first x-ray free-electron laser, the Office-of-Science-funded Linear Coherent Light Source-LCLS: the world's first free electron x-ray laser, with 100-fsec time resolution, tunable x-ray energies, a high rep rate, and a 10 order-of-magnitude increase in brightness over any other x-ray source--led to the realization that the scientific needs of NNSA and the broader scientific community could be well served by an LCLS HEDS endstation employing both short-pulse and high-energy optical lasers. Development of this concept has been well received in the community. NNSA requested a workshop on the applicability of LCLS to its needs. 'High Energy Density Science at the LCLS: NNSA Defense Programs Mission Need' was held in December 2006. The workshop provided strong support for the relevance of the endstation to NNSA strategic requirements. The range of science that was addressed covered a wide swath of the vast HEDS phase space. The unique possibilities provided by the LCLS in areas of intense interest to NNSA Defense Programs were discussed. The areas of focus included warm dense matter and equations of state, hot dense matter, and behavior of high-pressure materials under conditions of high strain-rate and extreme dynamic loading. Development of new and advanced diagnostic techniques was also addressed. This report lays out the relevant science, as brief summaries (Ch. II), expanded

  6. Diagnostics for ion beam driven high energy density physics experiments.

    Science.gov (United States)

    Bieniosek, F M; Henestroza, E; Lidia, S; Ni, P A

    2010-10-01

    Intense beams of heavy ions are capable of heating volumetric samples of matter to high energy density. Experiments are performed on the resulting warm dense matter (WDM) at the NDCX-I ion beam accelerator. The 0.3 MeV, 30 mA K(+) beam from NDCX-I heats foil targets by combined longitudinal and transverse neutralized drift compression of the ion beam. Both the compressed and uncompressed parts of the NDCX-I beam heat targets. The exotic state of matter (WDM) in these experiments requires specialized diagnostic techniques. We have developed a target chamber and fielded target diagnostics including a fast multichannel optical pyrometer, optical streak camera, laser Doppler-shift interferometer (Velocity Interferometer System for Any Reflector), beam transmission diagnostics, and high-speed gated cameras. We also present plans and opportunities for diagnostic development and a new target chamber for NDCX-II.

  7. Diagnostics for ion beam driven high energy density physics experimentsa)

    Science.gov (United States)

    Bieniosek, F. M.; Henestroza, E.; Lidia, S.; Ni, P. A.

    2010-10-01

    Intense beams of heavy ions are capable of heating volumetric samples of matter to high energy density. Experiments are performed on the resulting warm dense matter (WDM) at the NDCX-I ion beam accelerator. The 0.3 MeV, 30 mA K+ beam from NDCX-I heats foil targets by combined longitudinal and transverse neutralized drift compression of the ion beam. Both the compressed and uncompressed parts of the NDCX-I beam heat targets. The exotic state of matter (WDM) in these experiments requires specialized diagnostic techniques. We have developed a target chamber and fielded target diagnostics including a fast multichannel optical pyrometer, optical streak camera, laser Doppler-shift interferometer (Velocity Interferometer System for Any Reflector), beam transmission diagnostics, and high-speed gated cameras. We also present plans and opportunities for diagnostic development and a new target chamber for NDCX-II.

  8. A Fiber-Optic Sensor for Leak Detection in a Space Environment

    Science.gov (United States)

    Sinko, John E.; Korman, Valentin; Hendrickson, Adam; Polzin, Kurt A.

    2009-01-01

    A miniature fiber-optic, laser-based, interferometric leak detector is presented for application as a means to detect on-orbit gas leaks. The sensor employs a fiber-coupled modified Michelson interferometer to detect gas leaks by measuring an increase in gas density in the sensing region. Monitoring changes in the fringe pattern output by the interferometer allows for direct measurement of the gas density in the sensing region and, under the assumption of an equation of state, this can be used to obtain a pressure measurement. Measurements obtained over a pressure range from 20 mtorr to 760 torr using a prototypical interferometer on working gases of air, nitrogen, argon, and helium generally exhibit agreement with a theoretical prediction of the pressure increase required before an interference fringe completely moves over the detector. Additional measurements performed on various gases demonstrate the range of detectable species, measuring sub-torr pressure changes in the process. A high-fidelity measurement places the ultimate pressure resolution for this particular sensor configuration in the 10 mtorr range. Time-resolved data prove the capability of this sensor to detect fast gas flow phenomena associated with transients and pressure waves.

  9. Standing waves in fiber-optic interferometers.

    Science.gov (United States)

    de Haan, V; Santbergen, R; Tijssen, M; Zeman, M

    2011-10-10

    A study is presented giving the response of three types of fiber-optic interferometers by which a standing wave through an object is investigated. The three types are a Sagnac, Mach-Zehnder and Michelson-Morley interferometer. The response of the Mach-Zehnder interferometer is similar to the Sagnac interferometer. However, the Sagnac interferometer is much harder to study because of the fact that one input port and output port coincide. Further, the Mach-Zehnder interferometer has the advantage that the output ports are symmetric, reducing the systematic effects. Examples of standing wave light absorption in several simple objects are given. Attention is drawn to the influence of standing waves in fiber-optic interferometers with weak-absorbing layers incorporated. A method is described for how these can be theoretically analyzed and experimentally measured. Further experiments are needed for a thorough comparison between theory and experiment.

  10. Low-cost fiber-optic chemochromic hydrogen detector

    Energy Technology Data Exchange (ETDEWEB)

    Benson, D.K.; Tracy, C.E.; Hishmeh, G.; Ciszek, P.; Lee, S.H. [National Renewable Energy Lab., Golden, CO (United States)

    1998-08-01

    The ability to detect hydrogen gas leaks economically and with inherent safety is an important technology that could facilitate commercial acceptance of hydrogen fuel in various applications. In particular, hydrogen fueled passenger vehicles will require hydrogen leak detectors to signal the activation of safety devices such as shutoff valves, ventilating fans, alarms, etc. Such detectors may be required in several locations within a vehicle--wherever a leak could pose a safety hazard. It is therefore important that the detectors be very economical. This paper reports progress on the development of low-cost fiber-optic hydrogen detectors intended to meet the needs of a hydrogen-fueled passenger vehicle. In the design, the presence of hydrogen in air is sensed by a thin-film coating at the end of a polymer optical fiber. When the coating reacts reversibly with the hydrogen, its optical properties are changed. Light from a central electro-optic control unit is projected down the optical fiber where it is reflected from the sensor coating back to central optical detectors. A change in the reflected intensity indicates the presence of hydrogen. The fiber-optic detector offers inherent safety by removing all electrical power from the leak sites and offers reduced signal processing problems by minimizing electromagnetic interference. Critical detector performance requirements include high selectivity, response speed and durability as well as potential for low-cost production.

  11. Exploring high-density baryonic matter: Maximum freeze-out density

    Energy Technology Data Exchange (ETDEWEB)

    Randrup, Joergen [Lawrence Berkeley National Laboratory, Nuclear Science Division, Berkeley, CA (United States); Cleymans, Jean [University of Cape Town, UCT-CERN Research Centre and Department of Physics, Rondebosch (South Africa)

    2016-08-15

    The hadronic freeze-out line is calculated in terms of the net baryon density and the energy density instead of the usual T and μ{sub B}. This analysis makes it apparent that the freeze-out density exhibits a maximum as the collision energy is varied. This maximum freeze-out density has μ{sub B} = 400 - 500 MeV, which is above the critical value, and it is reached for a fixed-target bombarding energy of 20-30 GeV/N well within the parameters of the proposed NICA collider facility. (orig.)

  12. Development of high energy density electrical double layer capacitors

    Science.gov (United States)

    Devarajan, Thamarai selvi

    Electrochemical Double Layer capacitors (EDLCs) have shown themselves as a viable energy storage alternative. EDLCs have high power density, faster charge/discharge, wide operating temperature and long cycle life compared to batteries since it stores charge by physical separation. Despites all their advantages, their low energy density stand as a bottleneck for capacitors. This research aims to increase the energy density of EDLC without compromising the power density. Energy is proportional to the square of cell voltage. Cell voltage is mainly dependent on electrolyte breakdown. Electrolytes also provide ions for charge separation and conduction. Therefore various electrolytes (Solutes and Solvents) which can give high concentration, solubility and decomposition potential were characterized in the first part of the research. In that study, a novel ionic liquid OPBF4 had higher capacitance and comparable voltage window compared to commercial TEABF4 in Acetonitrile. However, the increased polarity of the fixed ring O-atom and the ion-ion interaction in OPBF4 was responsible for lowering its conductivity. Oxygenated ionic compounds with alkyl groups had lower stability due to beta elimination between two electron withdrawing atoms. Volume based thermodynamics and quantum chemical calculations were used to calculate ion size, HOMO/LUMO energies, and free energy changes and establish relationship with capacitance, redox potential and melting points respectively. In addition free energy of fusion was used to predict the melting point. Ion size had correlation with capacitance due to compact double layer formation. Free energy changes did not explain the differences in melting point and predicted dielectric constant was inconsistent with the polarity. This is presumably due to using Van der Waals volume instead of crystal structure volume and insufficient incorporation of polarization term. The HOMO/LUMO energies gave direct relation between oxidation and reduction

  13. Perpendicular patterned media for high density magnetic storage

    Science.gov (United States)

    Wong, Joyce Y.

    2000-11-01

    Current longitudinal thin-film media in magnetic hard- disk drives are facing an oncoming limit caused by the superparamagnetic effect, in which the individual grains in the medium become so small that they are no longer stable against thermal fluctuation. This situation is undesirable as the stored information may be lost within an unexpectedly short time frame. There have been several proposed solutions in addressing the superparamagnetic limit, and one of them is perpendicular patterned media. In this approach, a periodic array of magnetic pillars is defined lithographically on a non-magnetic substrate. Binary data of ``1'' or ``0'' can be stored in each of these elements, which have two possible magnetization directions perpendicular to the plane of the medium. In our perpendicular patterned media design, Ni columns of 150-230nm diameter with a 6:1 aspect ratio are embedded in an (AlGa)2O 3/GaAs substrate. The fabrication procedure uses a combination of high resolution electron beam lithography, dry etching, and electroplating. The high aspect ratio in the column is achieved by taking advantage of the high etching rate and selectivity of AlGaAs/GaAs over (AlGa)2O 3 in the Cl2 chemically assisted ion beam etching process. In addition to being a robust etching mask, the (AlGa)2O3 layer also plays an important role in the chemical mechanical polishing procedure to remove the overplated Ni mushrooms. Once the Ni columns are fabricated, magnetic characterization is performed using magnetic force microscopy and scanning magnetoresistance microscopy. The former measurement confirms that the electroplated Ni columns are magnetic while the latter determines whether the individual columns are stable enough to retain the recorded information. We have successfully demonstrated recording in our 170nm diameter Ni column array arranged in a square format using a commercial read/write head. This is the first demonstration of single magnetic column per bit data storage in a

  14. High Stocking Density Controls Phillyrea Angustifolia in Mediterranean Grasslands

    Science.gov (United States)

    Mesléard, François; Yavercovski, Nicole; Lefebvre, Gaétan; Willm, Loic; Bonis, Anne

    2017-03-01

    Extensive grazing applied in the form of low instantaneous pressure over a long period is a widespread management practice in protected areas. However this kind of stocking method does not always achieve the expected results, in particular because it fails to limit colonization by woody plants.This is the case in the relict xero-halophytic grasslands of the northern Mediterranean coastal region, subjected to widespread colonization by the shrub Phillyrea angustifolia despite the presence of extensive grazing. In this study, we investigated, for an equal annual stocking rate, the respective impact of high stocking density applied over a short period (mob grazing) and low stocking density applied over a long period on both P. angustifolia and herbaceous cover, using an in situ experimental design run for 7 years. Only mob grazing was effective both in controlling the establishment and increasing the mortality of P. angustifolia individuals. We did not find any difference after the 7 years of experimentation between the two stocking methods with regard to the herbaceous community parameters tested: species richness, diversity, evenness, contribution of annual characteristic species. By contrast, the exclusion of domestic grazing led to a strong reduction of these values.The use of mob grazing may be well suited for meeting conservation goals such as maintaining open habitats in these grasslands.

  15. High density collinear holographic data storage system (Conference Presentation)

    Science.gov (United States)

    Tan, Xiaodi; Horimai, Hideyoshi; Arai, Ryo; Ikeda, Junichi; Inoue, Mitsuteru; Lin, Xiao; Xu, Ke; Liu, Jinpeng; Huang, Yong

    2016-09-01

    Collinear holography has been good candidate for a volumetric recording technology of holographic data storage system (HDSS), because of there are not only large storage capacities, high transfer rates, but also the unique configuration, in which the information and reference beams are modulated co-axially by the same spatial light modulator, as a new read/write method for HDSS are very promising. The optical pickup can be designed as small as DVDs, and can be placed on one side of the recording media (disc). In the disc structure, the preformatted reflective layer is used for the focus/tracking servo and reading address information, and a dichroic mirror layer is used for detecting holographic recording information without interfering with the preformatted information. A 2-dimensional digital page data format is used and the shift-multiplexing method is employed to increase recording density. As servo technologies are being introduced to control the objective lens to be maintained precisely to the disc in the recording and reconstructing process, a vibration isolator is no longer necessary. In this paper, we introduced the principle of the collinear holography and its media structure of disc. Some results of experimental and theoretical studies suggest that it is a very effective method. We also discussed some methods to increase the recording density and data transfer rates of collinear holography using phase modulated page data format.

  16. High Current Density 2D/3D Esaki Tunnel Diodes

    CERN Document Server

    Krishnamoorthy, Sriram; Lee, Choong Hee; Zhang, Yuewei; McCulloch, William D; Johnson, Jared M; Hwang, Jinwoo; Wu, Yiying; Rajan, Siddharth

    2016-01-01

    The integration of two-dimensional materials such as transition metal dichalcogenides with bulk semiconductors offer interesting opportunities for 2D/3D heterojunction-based novel device structures without any constraints of lattice matching. By exploiting the favorable band alignment at the GaN/MoS2 heterojunction, an Esaki interband tunnel diode is demonstrated by transferring large area, Nb-doped, p-type MoS2 onto heavily n-doped GaN. A peak current density of 446 A/cm2 with repeatable room temperature negative differential resistance, peak to valley current ratio of 1.2, and minimal hysteresis was measured in the MoS2/GaN non-epitaxial tunnel diode. A high current density of 1 kA/cm2 was measured in the Zener mode (reverse bias) at -1 V bias. The GaN/MoS2 tunnel junction was also modeled by treating MoS2 as a bulk semiconductor, and the electrostatics at the 2D/3D interface was found to be crucial in explaining the experimentally observed device characteristics.

  17. Formation of FRCs on the Pulsed High Density Experiment

    Science.gov (United States)

    Andreason, Samuel; Slough, John

    2008-11-01

    The Pulsed High Density (PHD) experiment has been reassembled at a new facility with sufficient space to continue through the full acceleration and compression stages to reach breakeven. The intention here is to produce a large FRC, but remain in the kinetic regime where the FRC is stable and the transport sufficiently low that a Q > 1 plasma can be attained at moderate densities ˜ 10^23 m-3. During reassembly a more complete analysis of previous experimental results has been made. One of the issues in the early phase of the experiment was inefficient flux trapping during field reversal due to the large scale of the FRC source (0.4 m radius). The on-axis seed plasma was unable to diffuse out to the walls on a timescale commensurate with the introduction of bias fields. This resulted in more than half of the initial bias flux lost before sheath formation halted flux loss. An annular array of plasma sources has been constructed that solves this problem and greatly enhances the flux retention. Dynamic formation has been employed on PHD and analysis tools capable of interpreting the magnetic loop diagnostic array have been developed. Results with comparison to numerical models will be presented.

  18. OLEOPHOBIC AND HYDROPHOBIC FEATURE EXPERIMENTS OF FLUORINATED HIGH DENSITY POLYETHYLENE

    Institute of Scientific and Technical Information of China (English)

    杨宏伟; 魏贤勇; 费逸伟; 孙世安; 李晓越

    2013-01-01

    The surface performances of directly fluorinated high density polyethylene (HDPE) are studied with Fourier transform infrared (FT-IR) spectra ,scanning electron microscopy (SEM) and contact angle (CA) system . The SEM images show that there is a three-layer structure called the reaction ,virgin and boundary layer structure . The depth of fluorinated layer is 5.75 μm with 1 h fluorination time and 7.86 μm with 2 h . The depths are 5.46 μm and 5.07 μm when fluorine density is 2% and 1% ,respectively .CA indicates that the HDPE surface property becomes more hydrophobic with the increasing water contact angle from 78.5° to 104.5° .Oleophobic and hydrophobic features of HDPE are identified by comparison of mass change experiments .It is shown that the in-crement rate of fluorinated HDPE is much lower than that of un-fluorinated HDPE filled in neither distilled water nor jet fuel .

  19. Strongly interacting matter at high densities with a soliton model

    Science.gov (United States)

    Johnson, Charles Webster

    1998-12-01

    One of the major goals of modern nuclear physics is to explore the phase diagram of strongly interacting matter. The study of these 'extreme' conditions is the primary motivation for the construction of the Relativistic Heavy Ion Collider (RHIC) at Brookhaven National Laboratory which will accelerate nuclei to a center of mass (c.m.) energy of about 200 GeV/nucleon. From a theoretical perspective, a test of quantum chromodynamics (QCD) requires the expansion of the conditions examined from one phase point to the entire phase diagram of strongly-interacting matter. In the present work we focus attention on what happens when the density is increased, at low excitation energies. Experimental results from the Brookhaven Alternating Gradient Synchrotron (AGS) indicate that this regime may be tested in the 'full stopping' (maximum energy deposition) scenario achieved at the AGS having a c.m. collision energy of about 2.5 GeV/nucleon for two equal- mass heavy nuclei. Since the solution of QCD on nuclear length-scales is computationally prohibitive even on today's most powerful computers, progress in the theoretical description of high densities has come through the application of models incorporating some of the essential features of the full theory. The simplest such model is the MIT bag model. We use a significantly more sophisticated model, a nonlocal confining soliton model developed in part at Kent. This model has proven its value in the calculation of the properties of individual mesons and nucleons. In the present application, the many-soliton problem is addressed with the same model. We describe nuclear matter as a lattice of solitons and apply the Wigner-Seitz approximation to the lattice. This means that we consider spherical cells with one soliton centered in each, corresponding to the average properties of the lattice. The average density is then varied by changing the size of the Wigner-Seitz cell. To arrive at a solution, we need to solve a coupled set of

  20. A ferroelectric DRAM cell for high-density NVRAM's

    Science.gov (United States)

    Moazzami, Reza; Hu, Chenming; Shepherd, William H.

    1990-10-01

    The operation of a ferroelectric DRAM (dynamic random-access memory) cell for nonvolatile RAM (NVRAM) applications is described. Because polarization reversal only occurs during nonvolatile store/recall operations and not during read/write operations, ferroelectric fatigue is not a serious endurance problem. For a 3-V power supply, the worst-case effective silicon dioxide thickness of the unoptimized lead zirconate titanate film studied is less than 1.7 nm. The resistivity and endurance properties of ferroelectric films can be optimized by modifying the composition of the film. This cell can be the basis of a very-high-density NVRAM with practically no read/write cycle limit and at least 10 to the 10th nonvolatile store/recall cycles.

  1. [Cholesterol in serum high density lipoprotein fraction (author's transl)].

    Science.gov (United States)

    Schatz, C; Jeanblanc, B; Offner, M

    1980-11-22

    The risk of atheroma can be assessed and valid epidemiological surveys can be carried out by measuring cholesterol in serum high density lipoprotein fraction (HDL) and calculating the HDL cholesterol: VLDL + LDL ratio. This was done in 39 patients free from surgically confirmed atheromatous lesions and in 51 patients presenting with such lesions. Of the four different techniques used for separation in these patients (ultracentrifugation, precipitation with heparin-Mn2+, precipitation with phosphotungstate-Mg2+ and electrophoresis), precipitation with phosphotungstate-Mg/2+ seems to be the most suitable, since there is no degradation of the HDL fraction as during electrophoresis on polyacrylamide gel, and less floculation of the supernatant after separation. Contrary to ultracentrifugation, which requires sophisticated equipment and good technical skill, the technique is easily carried out.

  2. High-density polyethylene dosimetry by transvinylene FTIR analysis

    DEFF Research Database (Denmark)

    McLaughlin, W.L.; Silverman, J.; Al-Sheikhly, M.

    1999-01-01

    . The transvinylene response in air to gamma radiation is linear with dose and has relatively low yield compared with the response to electrons, whereas the response in deaerated polyethylene samples is also linear, but is more sensitive, and has negligible dose-rate dependence in its response to gamma rays...... and electrons. The useful dose range of 0.053 cm thick high-density polyethylene film (rho = 0.961 g cm(-3); melt index = 0.8 dg min(-1)), for irradiations by (60)Co gamma radiation and 2.0 and 0.4 MeV electron beams in deaerated atmosphere (Na gas), is about 50-10(3) kGy for FTIR transvinylene...

  3. 5th International conference on High Energy Density Laboratory Astrophysics

    CERN Document Server

    Kyrala, G.A

    2005-01-01

    During the past several years, research teams around the world have developed astrophysics-relevant utilizing high energy-density facilities such as intense lasers and z-pinches. Research is underway in many areas, such as compressible hydrodynamic mixing, strong shock phenomena, radiation flow, radiative shocks and jets, complex opacities, equations o fstat, and relativistic plasmas. Beyond this current research and the papers it is producing, plans are being made for the application, to astrophysics-relevant research, of the 2 MJ National Ignition Facility (NIF) laser at Lawrence Livermore National Laboratory; the 600 kj Ligne d'Intergration Laser (LIL) and the 2 MJ Laser Megajoule (LMJ) in Bordeaux, France; petawatt-range lasers now under construction around the world; and current and future Z pinches. The goal of this conference and these proceedings is to continue focusing and attention on this emerging research area. The conference brought together different scientists interested in this emerging new fi...

  4. Scoping study. High density polyethylene (HDPE) in salstone service

    Energy Technology Data Exchange (ETDEWEB)

    Phifer, Mark A. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2005-02-18

    An evaluation of the use of high density polyethylene (HDPE) geomembranes in Saltstone service has been conducted due to the potential benefits that could be derived from such usage. HDPE is one of the simplest hydrocarbon polymers and one of the most common polymers utilized in the production of geomembranes, which means that its costs are relatively low. Additionally, HDPE geomembranes have an extremely low permeability and an extremely low water vapor diffusional flux, which means that it is a good barrier to contaminant transport. The primary consideration in association with HDPE geomembranes in Saltstone service is the potential impact of Saltstone on the degradation of the HDPE geomembranes. Therefore, the evaluation documented herein has primarily focused upon the potential HDPE degradation in Saltstone service.

  5. The alterations in high density polyethylene properties with gamma irradiation

    Science.gov (United States)

    Zaki, M. F.; Elshaer, Y. H.; Taha, Doaa. H.

    2017-10-01

    In the present investigation, high density polyethylene (HDPE) polymer has been used to study the alterations in its properties under gamma-irradiation. Physico-chemical properties have been investigated with different spectroscopy techniques, Fourier Transform Infrared spectroscopy (FTIR), X-ray diffraction (XRD), biocompatibility properties, as well as, mechanical properties change. The FT-IR analysis shows the formation of new band at 1716 cm-1 that is attributed to the oxidation of irradiated polymer chains, which is due to the formation of carbonyl groups (C˭O). XRD patterns show that a decrease in the crystallite size and increase in the Full Width at Half Maximum (FWHM). This means that the crystallinity of irradiated samples is decreased with increase in gamma dose. The contact angle measurements show an increase in the surface free energy as the gamma irradiation increases. The measurements of mechanical properties of irradiated HDPE samples were discussed.

  6. Ultracold molecular Rydberg physics in a high density environment

    CERN Document Server

    Eiles, Matthew T; Robicheaux, F; Greene, Chris H

    2016-01-01

    Sufficiently high densities in Bose-Einstein condensates provide favorable conditions for the production of ultralong-range polyatomic molecules consisting of one Rydberg atom and a number of neutral ground state atoms. The chemical binding properties and electronic wave functions of these exotic molecules are investigated analytically via hybridized diatomic states. The effects of the molecular geometry on the system's properties are studied through comparisons of the adiabatic potential curves and electronic structures for both symmetric and randomly configured molecular geometries. General properties of these molecules with increasing numbers of constituent atoms and in different geometries are presented. These polyatomic states have spectral signatures that lead to non-Lorentzian line-profiles.

  7. Single-Readout High-Density Memristor Crossbar

    KAUST Repository

    Zidan, M. A.

    2016-01-07

    High-density memristor-crossbar architecture is a very promising technology for future computing systems. The simplicity of the gateless-crossbar structure is both its principal advantage and the source of undesired sneak-paths of current. This parasitic current could consume an enormous amount of energy and ruin the readout process. We introduce new adaptive-threshold readout techniques that utilize the locality and hierarchy properties of the computer-memory system to address the sneak-paths problem. The proposed methods require a single memory access per pixel for an array readout. Besides, the memristive crossbar consumes an order of magnitude less power than state-of-the-art readout techniques.

  8. Characterization of high density through silicon vias with spectral reflectometry.

    Science.gov (United States)

    Ku, Yi-Sha; Huang, Kuo Cheng; Hsu, Weite

    2011-03-28

    Measurement and control is an important step for production-worthy through silicon vias etch. We demonstrate the use and enhancement of an existing wafer metrology tool, spectral reflectometer by implementing novel theoretical model and measurement algorithm for high density through-silicon via (HDTSV) inspection. It is capable of measuring depth and depth variations of array vias by Discrete Fourier Transform (DFT) analysis in one shot measurement. Surface roughness of via bottom can also be extracted by scattering model fitting. Our non-destructive solution can measure TSV profile diameters as small as 5 μm and aspect ratios greater than 13:1. The measurement precision is in the range of 0.02 μm. Metrology results from actual 3D interconnect processing wafers are presented.

  9. Ultra-high current density thin-film Si diode

    Science.gov (United States)

    Wang, Qi

    2008-04-22

    A combination of a thin-film .mu.c-Si and a-Si:H containing diode structure characterized by an ultra-high current density that exceeds 1000 A/cm.sup.2, comprising: a substrate; a bottom metal layer disposed on the substrate; an n-layer of .mu.c-Si deposited the bottom metal layer; an i-layer of .mu.c-Si deposited on the n-layer; a buffer layer of a-Si:H deposited on the i-layer, a p-layer of .mu.c-Si deposited on the buffer layer; and a top metal layer deposited on the p-layer.

  10. Sulfurized activated carbon for high energy density supercapacitors

    Science.gov (United States)

    Huang, Yunxia; Candelaria, Stephanie L.; Li, Yanwei; Li, Zhimin; Tian, Jianjun; Zhang, Lili; Cao, Guozhong

    2014-04-01

    Sulfurized activated carbon (SAC), made by coating the pore surface with thiophenic sulfur functional groups from the pyrolysis of sulfur flakes, were characterized and tested for supercapacitor applications. From X-ray photoelectron spectroscopy (XPS), the sulfur content in the SAC was found to be 2.7 at%. Electrochemical properties from potentiostatic and galvanostatic measurements, and electrochemical impedance spectroscopy (EIS) were used to evaluate the effect of sulfur on porous carbon electrodes. The SAC electrode exhibits better conductivity, and an obvious increase in specific capacitance that is almost 40% higher than plain activated carbons (ACs) electrode at a high current density of 1.4 A g-1. The proposed mechanism for improved conductivity and capacitive performance due to the sulfur functional groups on ACs will be discussed.

  11. High-density avalanche chambers for positron emission tomography

    Energy Technology Data Exchange (ETDEWEB)

    Manfrass, P.; Enghardt, W.; Fromm, W.D.; Wohlfarth, D.; Hohmuth, K.

    1988-12-15

    A positron tomograph for radiopharmaceutical and medical research is under construction. In its final stage it will cover six high-density avalanche chambers (HIDAC) in a hexagonal arrangement. Each detector with a sensitive area of 50x28 cm/sup 2/ will consist of a stack of four pairs of multihole photon-to-electron converters with a multiwire proportional counter (MWPC) in between. An experimental investigation of detector properties as time and spatial resolutions as well as detector efficiency in dependence to converter structure, electric field strength and counting gas mixture preceded the final design of these detectors. Results of these studies are outlined. Furthermore, longitudinal tomograms taken with a stationary test camera are presented.

  12. High-density percutaneous chronic connector for neural prosthetics

    Science.gov (United States)

    Shah, Kedar G.; Bennett, William J.; Pannu, Satinderpall S.

    2015-09-22

    A high density percutaneous chronic connector, having first and second connector structures each having an array of magnets surrounding a mounting cavity. A first electrical feedthrough array is seated in the mounting cavity of the first connector structure and a second electrical feedthrough array is seated in the mounting cavity of the second connector structure, with a feedthrough interconnect matrix positioned between a top side of the first electrical feedthrough array and a bottom side of the second electrical feedthrough array to electrically connect the first electrical feedthrough array to the second electrical feedthrough array. The two arrays of magnets are arranged to attract in a first angular position which connects the first and second connector structures together and electrically connects the percutaneously connected device to the external electronics, and to repel in a second angular position to facilitate removal of the second connector structure from the first connector structure.

  13. CENTER FOR PULSED POWER DRIVEN HIGH ENERGY DENSITY PLASMA STUDIES

    Energy Technology Data Exchange (ETDEWEB)

    Professor Bruce R. Kusse; Professor David A. Hammer

    2007-04-18

    This annual report summarizes the activities of the Cornell Center for Pulsed-Power-Driven High-Energy-Density Plasma Studies, for the 12-month period October 1, 2005-September 30, 2006. This period corresponds to the first year of the two-year extension (awarded in October, 2005) to the original 3-year NNSA/DOE Cooperative Agreement with Cornell, DE-FC03-02NA00057. As such, the period covered in this report also corresponds to the fourth year of the (now) 5-year term of the Cooperative Agreement. The participants, in addition to Cornell University, include Imperial College, London (IC), the University of Nevada, Reno (UNR), the University of Rochester (UR), the Weizmann Institute of Science (WSI), and the P.N. Lebedev Physical Institute (LPI), Moscow. A listing of all faculty, technical staff and students, both graduate and undergraduate, who participated in Center research activities during the year in question is given in Appendix A.

  14. Methods and systems for rapid prototyping of high density circuits

    Science.gov (United States)

    Palmer, Jeremy A.; Davis, Donald W.; Chavez, Bart D.; Gallegos, Phillip L.; Wicker, Ryan B.; Medina, Francisco R.

    2008-09-02

    A preferred embodiment provides, for example, a system and method of integrating fluid media dispensing technology such as direct-write (DW) technologies with rapid prototyping (RP) technologies such as stereolithography (SL) to provide increased micro-fabrication and micro-stereolithography. A preferred embodiment of the present invention also provides, for example, a system and method for Rapid Prototyping High Density Circuit (RPHDC) manufacturing of solderless connectors and pilot devices with terminal geometries that are compatible with DW mechanisms and reduce contact resistance where the electrical system is encapsulated within structural members and manual electrical connections are eliminated in favor of automated DW traces. A preferred embodiment further provides, for example, a method of rapid prototyping comprising: fabricating a part layer using stereolithography and depositing thermally curable media onto the part layer using a fluid dispensing apparatus.

  15. Thermolysis of High-Density Polyethylene to Petroleum Products

    Directory of Open Access Journals (Sweden)

    Sachin Kumar

    2013-01-01

    Full Text Available Thermal degradation of plastic polymers is becoming an increasingly important method for the conversion of plastic materials into valuable chemicals and oil products. In this work, virgin high-density polyethylene (HDPE was chosen as a material for pyrolysis. A simple pyrolysis reactor system has been used to pyrolyse virgin HDPE with an objective to optimize the liquid product yield at a temperature range of 400°C to 550°C. The chemical analysis of the HDPE pyrolytic oil showed the presence of functional groups such as alkanes, alkenes, alcohols, ethers, carboxylic acids, esters, and phenyl ring substitution bands. The composition of the pyrolytic oil was analyzed using GC-MS, and it was found that the main constituents were n-Octadecane, n-Heptadecane, 1-Pentadecene, Octadecane, Pentadecane, and 1-Nonadecene. The physical properties of the obtained pyrolytic oil were close to those of mixture of petroleum products.

  16. Flexible asymmetric supercapacitors with high energy and high power density in aqueous electrolytes.

    Science.gov (United States)

    Cheng, Yingwen; Zhang, Hongbo; Lu, Songtao; Varanasi, Chakrapani V; Liu, Jie

    2013-02-07

    Supercapacitors with both high energy and high power densities are critical for many practical applications. In this paper, we discuss the design and demonstrate the fabrication of flexible asymmetric supercapacitors based on nanocomposite electrodes of MnO(2), activated carbon, carbon nanotubes and graphene. The combined unique properties of each of these components enable highly flexible and mechanically strong films that can serve as electrodes directly without using any current collectors or binders. Using these flexible electrodes and a roll-up approach, asymmetric supercapacitors with 2 V working voltage were successfully fabricated. The fabricated device showed excellent rate capability, with 78% of the original capacitance retained when the scan rate was increased from 2 mV s(-1) to 500 mV s(-1). Owing to the unique composite structure, these supercapacitors were able to deliver high energy density (24 W h kg(-1)) under high power density (7.8 kW kg(-1)) conditions. These features could enable supercapacitor based energy storage systems to be very attractive for a variety of critical applications, such as the power sources in hybrid electric vehicles and the back-up powers for wind and solar energy, where both high energy density and high power density are required.

  17. Extended MHD Effects in High Energy Density Experiments

    Science.gov (United States)

    Seyler, Charles

    2016-10-01

    The MHD model is the workhorse for computational modeling of HEDP experiments. Plasma models are inheritably limited in scope, but MHD is expected to be a very good model for studying plasmas at the high densities attained in HEDP experiments. There are, however, important ways in which MHD fails to adequately describe the results, most notably due to the omission of the Hall term in the Ohm's law (a form of extended MHD or XMHD). This talk will discuss these failings by directly comparing simulations of MHD and XMHD for particularly relevant cases. The methodology is to simulate HEDP experiments using a Hall-MHD (HMHD) code based on a highly accurate and robust Discontinuous Galerkin method, and by comparison of HMHD to MHD draw conclusions about the impact of the Hall term. We focus on simulating two experimental pulsed power machines under various scenarios. We examine the MagLIF experiment on the Z-machine at Sandia National Laboratories and liner experiments on the COBRA machine at Cornell. For the MagLIF experiment we find that power flow in the feed leads to low density plasma ablation into the region surrounding the liner. The inflow of this plasma compresses axial magnetic flux onto the liner. In MHD this axial flux tends to resistively decay, whereas in HMHD a force-free current layer sustains the axial flux on the liner leading to a larger ratio of axial to azimuthal flux. During the liner compression the magneto-Rayleigh-Taylor instability leads to helical perturbations due to minimization of field line bending. Simulations of a cylindrical liner using the COBRA machine parameters can under certain conditions exhibit amplification of an axial field due to a force-free low-density current layer separated by some distance from the liner. This results in a configuration in which there is predominately axial field on the liner inside the current layer and azimuthal field outside the layer. We are currently attempting to experimentally verify the simulation

  18. Modulation of low-density lipoprotein-induced inhibition of intercellular communication by antioxidants and high-density lipoproteins

    NARCIS (Netherlands)

    Zwijsen, R M; de Haan, L. H. J.; Kuivenhoven, J A; Nusselder, I C

    1991-01-01

    In order to study the capacity of antioxidants and high-density lipoproteins (HDL) to modulate the effects of low-density lipoprotein (LDL) on intercellular communication, arterial smooth muscle cells and a dye transfer method were used. LDL, in contrast to HDL, inhibited the communication between a

  19. Modulation of low-density lipoprotein-induced inhibition of intercellular communication by antioxidants and high-density lipoproteins

    NARCIS (Netherlands)

    Zwijsen, R M; de Haan, L. H. J.; Kuivenhoven, J A; Nusselder, I C

    In order to study the capacity of antioxidants and high-density lipoproteins (HDL) to modulate the effects of low-density lipoprotein (LDL) on intercellular communication, arterial smooth muscle cells and a dye transfer method were used. LDL, in contrast to HDL, inhibited the communication between

  20. Numerical methods for high-dimensional probability density function equations

    Science.gov (United States)

    Cho, H.; Venturi, D.; Karniadakis, G. E.

    2016-01-01

    In this paper we address the problem of computing the numerical solution to kinetic partial differential equations involving many phase variables. These types of equations arise naturally in many different areas of mathematical physics, e.g., in particle systems (Liouville and Boltzmann equations), stochastic dynamical systems (Fokker-Planck and Dostupov-Pugachev equations), random wave theory (Malakhov-Saichev equations) and coarse-grained stochastic systems (Mori-Zwanzig equations). We propose three different classes of new algorithms addressing high-dimensionality: The first one is based on separated series expansions resulting in a sequence of low-dimensional problems that can be solved recursively and in parallel by using alternating direction methods. The second class of algorithms relies on truncation of interaction in low-orders that resembles the Bogoliubov-Born-Green-Kirkwood-Yvon (BBGKY) framework of kinetic gas theory and it yields a hierarchy of coupled probability density function equations. The third class of algorithms is based on high-dimensional model representations, e.g., the ANOVA method and probabilistic collocation methods. A common feature of all these approaches is that they are reducible to the problem of computing the solution to high-dimensional equations via a sequence of low-dimensional problems. The effectiveness of the new algorithms is demonstrated in numerical examples involving nonlinear stochastic dynamical systems and partial differential equations, with up to 120 variables.

  1. Numerical methods for high-dimensional probability density function equations

    Energy Technology Data Exchange (ETDEWEB)

    Cho, H. [Department of Mathematics, University of Maryland College Park, College Park, MD 20742 (United States); Venturi, D. [Department of Applied Mathematics and Statistics, University of California Santa Cruz, Santa Cruz, CA 95064 (United States); Karniadakis, G.E., E-mail: gk@dam.brown.edu [Division of Applied Mathematics, Brown University, Providence, RI 02912 (United States)

    2016-01-15

    In this paper we address the problem of computing the numerical solution to kinetic partial differential equations involving many phase variables. These types of equations arise naturally in many different areas of mathematical physics, e.g., in particle systems (Liouville and Boltzmann equations), stochastic dynamical systems (Fokker–Planck and Dostupov–Pugachev equations), random wave theory (Malakhov–Saichev equations) and coarse-grained stochastic systems (Mori–Zwanzig equations). We propose three different classes of new algorithms addressing high-dimensionality: The first one is based on separated series expansions resulting in a sequence of low-dimensional problems that can be solved recursively and in parallel by using alternating direction methods. The second class of algorithms relies on truncation of interaction in low-orders that resembles the Bogoliubov–Born–Green–Kirkwood–Yvon (BBGKY) framework of kinetic gas theory and it yields a hierarchy of coupled probability density function equations. The third class of algorithms is based on high-dimensional model representations, e.g., the ANOVA method and probabilistic collocation methods. A common feature of all these approaches is that they are reducible to the problem of computing the solution to high-dimensional equations via a sequence of low-dimensional problems. The effectiveness of the new algorithms is demonstrated in numerical examples involving nonlinear stochastic dynamical systems and partial differential equations, with up to 120 variables.

  2. Probucol alleviates atherosclerosis and improves high density lipoprotein function

    Directory of Open Access Journals (Sweden)

    Zhong Jian-Kai

    2011-11-01

    Full Text Available Abstract Background Probucol is a unique hypolipidemic agent that decreases high density lipoprotein cholesterol (HDL-C. However, it is not definite that whether probucol hinders the progression of atherosclerosis by improving HDL function. Methods Eighteen New Zealand White rabbits were randomly divided into the control, atherosclerosis and probucol groups. Control group were fed a regular diet; the atherosclerosis group received a high fat diet, and the probucol group received the high fat diet plus probucol. Hepatocytes and peritoneal macrophages were isolated for [3H] labeled cholesterol efflux rates and expression of ABCA1 and SR-B1 at gene and protein levels; venous blood was collected for serum paraoxonase 1, myeloperoxidase activity and lipid analysis. Aorta were prepared for morphologic and immunohistochemical analysis after 12 weeks. Results Compared to the atherosclerosis group, the paraoxonase 1 activity, cholesterol efflux rates, expression of ABCA1 and SR-BI in hepatocytes and peritoneal macrophages, and the level of ABCA1 and SR-BI in aortic lesions were remarkably improved in the probucol group, But the serum HDL cholesterol concentration, myeloperoxidase activity, the IMT and the percentage plaque area of aorta were significantly decreased. Conclusion Probucol alleviated atherosclerosis by improving HDL function. The mechanisms include accelerating the process of reverse cholesterol transport, improving the anti-inflammatory and anti-oxidant functions.

  3. Acrolein impairs the cholesterol transport functions of high density lipoproteins.

    Science.gov (United States)

    Chadwick, Alexandra C; Holme, Rebecca L; Chen, Yiliang; Thomas, Michael J; Sorci-Thomas, Mary G; Silverstein, Roy L; Pritchard, Kirkwood A; Sahoo, Daisy

    2015-01-01

    High density lipoproteins (HDL) are considered athero-protective, primarily due to their role in reverse cholesterol transport, where they transport cholesterol from peripheral tissues to the liver for excretion. The current study was designed to determine the impact of HDL modification by acrolein, a highly reactive aldehyde found in high abundance in cigarette smoke, on the cholesterol transport functions of HDL. HDL was chemically-modified with acrolein and immunoblot and mass spectrometry analyses confirmed apolipoprotein crosslinking, as well as acrolein adducts on apolipoproteins A-I and A-II. The ability of acrolein-modified HDL (acro-HDL) to serve as an acceptor of free cholesterol (FC) from COS-7 cells transiently expressing SR-BI was significantly decreased. Further, in contrast to native HDL, acro-HDL promotes higher neutral lipid accumulation in murine macrophages as judged by Oil Red O staining. The ability of acro-HDL to mediate efficient selective uptake of HDL-cholesteryl esters (CE) into SR-BI-expressing cells was reduced compared to native HDL. Together, the findings from our studies suggest that acrolein modification of HDL produces a dysfunctional particle that may ultimately promote atherogenesis by impairing functions that are critical in the reverse cholesterol transport pathway.

  4. SELDI-TOF mass spectrometry of High-Density Lipoprotein

    Directory of Open Access Journals (Sweden)

    Rezaee Farhad

    2007-09-01

    Full Text Available Abstract Background High-Density Lipoprotein (HDL, one of the main plasma lipoproteins, serves as a docking station for proteins involved in inflammation, coagulation, and lipid metabolism. Methods To elucidate the protein composition of HDL, we employed SELDI-TOF mass spectrometry as a potential high-throughput proteomic candidate for protein profiling of HDL. HDL derived from normolipemic individuals was captured on PS20 protein-chips using covalently bound antibodies against apo A-I or A-II. Results After optimisation, on-chip capture of HDL particles directly from plasma or from pre-purified HDL resulted in comparable fingerprints confirming specific capture of HDL. Depending on the capture antibody some differences in the fingerprint were observed. The most detailed fingerprint was observed up to 50 kDa; approximately 95 peaks were detected in the 3–50 kDa molecular mass range. Between 50 and 160 kDa, 27 more peaks were detected. Conclusion Based on these results, SELDI-TOF MS may be a suitable high-throughput candidate for HDL protein profiling and marker search. This approach may be used to i investigate the underlying mechanisms that lead to increased atherothrombotic risk and ii to investigate the atherothrombotic state of an individual.

  5. High-Density Infrared Surface Treatments of Refractories

    Energy Technology Data Exchange (ETDEWEB)

    Tiegs, T.N.

    2005-03-31

    Refractory materials play a crucial role in all energy-intensive industries and are truly a crosscutting technology for the Industries of the Future (IOF). One of the major mechanisms for the degradation of refractories and a general decrease in their performance has been the penetration and corrosion by molten metals or glass. Methods and materials that would reduce the penetration, wetting, and corrosive chemistry would significantly improve refractory performance and also maintain the quality of the processed liquid, be it metal or glass. This report presents the results of an R&D project aimed at investigating the use of high-density infrared (HDI) heating to surface treat refractories to improve their performance. The project was a joint effort between Oak Ridge National Laboratory (ORNL) and the University of Missouri-Rolla (UMR). HDI is capable of heating the near-surface region of materials to very high temperatures where sintering, diffusion, and melting can occur. The intended benefits of HDI processing of refractories were to (1) reduce surface porosity (by essentially sealing the surface to prevent liquid penetration), (2) allow surface chemistry changes to be performed by bonding an adherent coating onto the underlying refractory (in order to inhibit wetting and/or improve corrosion resistance), and (3) produce noncontact refractories with high-emissivity surface coatings.

  6. Cyclic Oxidation of High Mo, Reduced Density Superalloys

    Directory of Open Access Journals (Sweden)

    James L. Smialek

    2015-11-01

    Full Text Available Cyclic oxidation was characterized as part of a statistically designed, 12-alloy compositional study of 2nd generation single crystal superalloys as part of a broader study to co-optimize density, creep strength, and cyclic oxidation. The primary modification was a replacement of 5 wt. % W by 7% or 12% Mo for density reductions of 2%–7%. Compositions at two levels of Mo, Cr, Co, and Re were produced, along with a midpoint composition. Initially, polycrystalline vacuum induction samples were screened in 1100 °C cyclic furnace tests using 1 h cycles for 200 h. The behavior was primarily delimited by Cr content, producing final weight changes of −40 mg/cm2 to −10 mg/cm2 for 0% Cr alloys and −2 mg/cm2 to +1 mg/cm2 for 5% Cr alloys. Accordingly, a multiple linear regression fit yielded an equation showing a strong positive Cr effect and lesser negative effects of Co and Mo. The results for 5% Cr alloys compare well to −1 mg/cm2, and +0.5 mg/cm2 for Rene′ N4 and Rene′ N5 (or Rene′ N6, respectively. Scale phases commonly identified were Al2O3, NiAl2O4, NiTa2O6, and NiO, with (Ni,CoMoO4 found only on the least resistant alloys having 0% Cr and 12% Mo. Scale microstructures were complex and reflected variations in the regional spallation history. Large faceted NiO grains and fine NiTa2O6 particles distributed along NiAl2O4 grain boundaries were typical distinctive features. NiMoO4 formation, decomposition, and volatility occurred for a few high Mo compositions. A creep, density, phase stability, and oxidation balanced 5% Cr, 10% Co, 7% Mo, and 3% Re alloy was selected to be taken forward for more extensive evaluations in single crystal form.

  7. Effects of gamma irradiation on polypropylene, polypropylene + high density polyethylene and polypropylene + high density polyethylene + wood flour

    Energy Technology Data Exchange (ETDEWEB)

    Reyes, J.; Albano, C.; Davidson, E.; Poleo, R. [Universidad Central de Venezuela, Caracas (Venezuela). Escuela de Quimica; Gonzalez, J.; Ichazo, M. [Universidad Simon Bolivar, Dept. de Mecanica, Caracas (Venezuela); Chipara, M. [Research Institute for Electrotechnics, Bucharest (Romania)

    2001-04-01

    The effect of the gamma-irradiation on the mechanical properties of the composites, Polypropylene (PP), PP+high density Polyethylene (HDPE), PP+ HDPE+wood flour, where HDPE is virgin and recycled, was studied. This paper discusses the behavior of the composites after exposure to various doses of gamma irradiation (1-7 MRads) in the presence of oxygen. The dependence of mechanical properties on the integral dose for a constant dose rate of 0.48 MRads/h confirms the influence of the irradiation. Strong effects on the elongation at break and break strength is noticed. The mathematical analysis suggests for the PP+r-HDPE a bimolecular process of the elongation at break. On the order hand, for the PP+HDPE a complex process is represented for a three exponential equation. (orig.)

  8. Individual tree detection based on densities of high points of high resolution airborne lidar

    NARCIS (Netherlands)

    Abd Rahman, M.Z.; Gorte, B.G.H.

    2008-01-01

    The retrieval of individual tree location from Airborne LiDAR has focused largely on utilizing canopy height. However, high resolution Airborne LiDAR offers another source of information for tree detection. This paper presents a new method for tree detection based on high points’ densities from a

  9. Tree crown delineation from high resolution airborne LiDAR based on densities of high points

    NARCIS (Netherlands)

    Rahman, M.Z.A.; Gorte, B.G.H.

    2009-01-01

    Tree detection and tree crown delineation from Airborne LiDAR has been focusing mostly on utilizing the canopy height model (CHM). This paper presents a method for individual tree crown delineation based on densities of high points (DHP) from the high resolution Airborne LiDAR. The DHP method relies

  10. High-density myoelectric pattern recognition toward improved stroke rehabilitation.

    Science.gov (United States)

    Zhang, Xu; Zhou, Ping

    2012-06-01

    Myoelectric pattern-recognition techniques have been developed to infer user's intention of performing different functional movements. Thus electromyogram (EMG) can be used as control signals of assisted devices for people with disabilities. Pattern-recognition-based myoelectric control systems have rarely been designed for stroke survivors. Aiming at developing such a system for improved stroke rehabilitation, this study assessed detection of the affected limb's movement intention using high-density surface EMG recording and pattern-recognition techniques. Surface EMG signals comprised of 89 channels were recorded from 12 hemiparetic stroke subjects while they tried to perform 20 different arm, hand, and finger/thumb movements involving the affected limb. A series of pattern-recognition algorithms were implemented to identify the intended tasks of each stroke subject. High classification accuracies (96.1% ± 4.3%) were achieved, indicating that substantial motor control information can be extracted from paretic muscles of stroke survivors. Such information may potentially facilitate improved stroke rehabilitation.

  11. High-Density Carbon (HDC) Ablator for NIC Ignition Capsules

    Science.gov (United States)

    Ho, D.; Haan, S.; Salmonson, J.; Milovich, J.; Callahan, D.

    2012-10-01

    HDC ablators show high performance based on simulations, despite the fact that the shorter pulses for HDC capsules result in higher M-band radiation compared to that for plastic capsules. HDC capsules have good 1-D performance because HDC has relatively high density (3.5 g/cc), which results in a thinner ablator that absorbs more radiation. HDC ablators have good 2-D performance because the ablator surface is more than an order-of-magnitude smoother than Be or plastic ablators. Refreeze of the ablator near the fuel region can be avoided by appropriate dopant placement. Here we present two HDC ignition designs doped with W and Si. For the design with maximum W concentration of 1.0 at% (and respectively with maximum Si concentration of 2.0 at%): peak velocity = 0.395 (0.397) mm/ns, mass weighted fuel entropy = 0.463 (0.469) kJ/mg/eV, peak core hydrodynamic stagnation pressure = 690 (780) Gbar, and yield = 17.3 (20.2) MJ. 2-D simulations show that yield is close to 80% YoC even with 2.5x of nominal surface roughness on all surfaces. The clean fuel fraction is about 75% at peak velocity. Doping HDC with the required concentration of W and Si is in progress. A first undoped HDC Symcap is scheduled to be fielded later this year.

  12. Altered activation of endothelial anti- and proapoptotic pathways by high-density lipoprotein from patients with coronary artery disease: role of high-density lipoprotein-proteome remodeling

    National Research Council Canada - National Science Library

    Riwanto, Meliana; Rohrer, Lucia; Roschitzki, Bernd; Besler, Christian; Mocharla, Pavani; Mueller, Maja; Perisa, Damir; Heinrich, Kathrin; Altwegg, Lukas; von Eckardstein, Arnold; Lüscher, Thomas F; Landmesser, Ulf

    2013-01-01

    ...). High-density lipoprotein from healthy subjects (HDL(Healthy)) has been proposed to exert endothelial antiapoptotic effects that may represent an important antiatherogenic property of the lipoprotein...

  13. Symmetry energy systematics and its high density behavior

    CERN Document Server

    Chen, Lie-Wen

    2015-01-01

    We explore the systematics of the density dependence of nuclear matter symmetry energy in the ambit of microscopic calculations with various energy density functionals, and find that the symmetry energy from subsaturation density to supra-saturation density can be well determined by three characteristic parameters of the symmetry energy at saturation density $\\rho_0 $, i.e., the magnitude $E_{\\text{sym}}({\\rho_0 })$, the density slope $L$ and the density curvature $K_{\\text{sym}}$. This finding opens a new window to constrain the supra-saturation density behavior of the symmetry energy from its (sub-)saturation density behavior. In particular, we obtain $L=46.7 \\pm 12.8$ MeV and $K_{\\text{sym}}=-166.9 \\pm 168.3$ MeV as well as $E_{\\text{sym}}({2\\rho _{0}}) \\approx 40.2 \\pm 12.8$ MeV and $L({2\\rho _{0}}) \\approx 8.9 \\pm 108.7$ MeV based on the present knowledge of $E_{\\text{sym}}({\\rho_{0}}) = 32.5 \\pm 0.5$ MeV, $E_{\\text{sym}}({\\rho_c}) = 26.65 \\pm 0.2$ MeV and $L({\\rho_c}) = 46.0 \\pm 4.5$ MeV at $\\rho_{\\rm{c...

  14. Magnetic Shielding Method and Experiment Study of Inertial Measurement Unit Based on High Precision Fiber-optic Gyroscope%高精度光纤IMU的磁屏蔽方法及实验研究

    Institute of Scientific and Technical Information of China (English)

    李金涛; 房建成

    2011-01-01

    惯性测量单元(IMU)是位置姿态系统(POS)的核心部分,IMU的精度很大程度上决定着POS精度.由于高精度光纤陀螺(FOG)的光纤线圈对磁场敏感,基于高精度FOG的IMU精度会受磁场影响而降低.本文研究了FOG磁敏感性机理,通过实验得出高精度光纤IMU对磁场敏感的结论.采用电磁场有限元分析软件Ansoft Maxwell研究了磁屏蔽体采用不同材料、不同厚度时的磁屏蔽效能(SE),并进行了IMU磁屏蔽结构设计.通过亥姆霍兹线圈测试得到的磁屏蔽体实际屏蔽效能最高为48.20 dB,与有限元分析结果基本一致.转台环境测试表明:屏蔽体使FOG漂移减小到9%以上;亥姆霍兹线圈测试表明:通过磁屏蔽使FOG零偏磁敏感度衰减2~21 dB,漂移磁敏感度衰减9~23 dB,对提高光纤IMU测试和应用精度以及机载环境适应性有重要意义.%The inertial measurement unit (IMU) is the core of a position and orientation system (POS), whose accuracy has a crucial impact on POS accuracy. But the IMU accuracy based on high precision fiber-optic gyroscope (FOG) is degraded because of the sensitivity of the FOG fiber coil to the magnetic field. This paper studied the magnetic sensitivity mechanism of the FOG. And through experimental study reached the conclusion that the IMU based on a high precision FOG is also sensitive to the magnetic field. An IMU shielding is designed, and its shielding effectiveness (SE) is analyzed by electromagnetic field finite element analysis software Ansoft Maxwell for different materials with different thicknesses. The best SE of 48.20 Db is achieved with a Helmholtz coil test, which is consistent with the results of the finite element analysis. The turn table test shows that a reduction of over 9% of the FOG drift is achieved with the enclosure. The Helmholtz coil test with magnetic shielding demonstrates that the bias and drift magnetic sensitivity of the FOG are decreased by 2-21 Db and 9-23 Db

  15. Increased illumination uniformity and reduced photodamage offered by the Lissajous scanning in fiber-optic two-photon endomicroscopy.

    Science.gov (United States)

    Liang, Wenxuan; Murari, Kartikeya; Zhang, Yuying; Chen, Yongping; Li, Ming-Jun; Li, Xingde

    2012-02-01

    We compare the illumination uniformity and the associated effects of the spiral and Lissajous scanning patterns that are commonly used in an endomicroscope. Theoretical analyses and numerical simulations were first performed to quantitatively investigate the area illumination density in the spiral scanning pattern. The results revealed the potential problem of manifest photodamage due to the very high illumination density in the center of the spiral scan. Similar analyses of the Lissajous scanning pattern, which can be conveniently implemented on the same endomicroscope with no hardware modifications, showed a more uniform illumination density with about an 80-fold reduction in the peak illumination density. To underscore the benefit offered by the improved illumination uniformity, we conducted in vitro two-photon fluorescence imaging of cultured cells stained with a LIVE/DEAD viability assay using our home-built, fiber-optic, two-channel endomicroscopy system. Both the spiral and the Lissajous scans were implemented. Our experimental results showed that cells near the spiral scan center experienced obvious photodamage, whereas cells remained alive over the entire region under the Lissajous beam scanning, confirming the predicted advantage offered by the Lissajous scan over this spiral scan in an endomicroscopy setting.

  16. Fiber-optic Michelson interferometer using an optical power divider.

    Science.gov (United States)

    Imai, M; Ohashi, T; Ohtsuka, Y

    1980-10-01

    A fiber-optic interferometer consisting of a multimode fiber-optical power divider was constructed in the Michelson arrangement and applied to measure a micrometer-order displacement of the vibrating object based on an optical homodyne technique. Improvement in the sensitivity of the apparatus is discussed from the viewpoint of increasing the minimum detectable beat signal.

  17. Fiber-optic interferometric acoustic sensors for wind tunnel applications

    Science.gov (United States)

    Cho, Y. C.

    1993-01-01

    Progress in developing fiber-optic interferometric sensors for aeroacoustic measurements in wind tunnels, performed under the NASA program, is reported. Preliminary results show that the fiber-optic interferometer sensor array is a powerful instrument for solving complex acoustic measurement problems in wind tunnels, which cannot be resolved with the conventional transducer technique.

  18. Fiber-optic interferometric acoustic sensors for wind tunnel applications

    Science.gov (United States)

    Cho, Y. C.

    1993-01-01

    Progress in developing fiber-optic interferometric sensors for aeroacoustic measurements in wind tunnels, performed under the NASA program, is reported. Preliminary results show that the fiber-optic interferometer sensor array is a powerful instrument for solving complex acoustic measurement problems in wind tunnels, which cannot be resolved with the conventional transducer technique.

  19. High-density lipoprotein proteome dynamics in human endotoxemia

    Directory of Open Access Journals (Sweden)

    Stroes Erik SG

    2011-06-01

    Full Text Available Abstract Background A large variety of proteins involved in inflammation, coagulation, lipid-oxidation and lipid metabolism have been associated with high-density lipoprotein (HDL and it is anticipated that changes in the HDL proteome have implications for the multiple functions of HDL. Here, SELDI-TOF mass spectrometry (MS was used to study the dynamic changes of HDL protein composition in a human experimental low-dose endotoxemia model. Ten healthy men with low HDL cholesterol (0.7+/-0.1 mmol/L and 10 men with high HDL cholesterol levels (1.9+/-0.4 mmol/L were challenged with endotoxin (LPS intravenously (1 ng/kg bodyweight. We previously showed that subjects with low HDL cholesterol are more susceptible to an inflammatory challenge. The current study tested the hypothesis that this discrepancy may be related to differences in the HDL proteome. Results Plasma drawn at 7 time-points over a 24 hour time period after LPS challenge was used for direct capture of HDL using antibodies against apolipoprotein A-I followed by subsequent SELDI-TOF MS profiling. Upon LPS administration, profound changes in 21 markers (adjusted p-value Conclusions This study shows that the semi-quantitative differences in the HDL proteome as assessed by SELDI-TOF MS cannot explain why subjects with low HDL cholesterol are more susceptible to a challenge with LPS than those with high HDL cholesterol. Instead the results indicate that hierarchical clustering could be useful to predict HDL functionality in acute phase responses towards LPS.

  20. High density plasmas and new diagnostics: An overview (invited)

    Energy Technology Data Exchange (ETDEWEB)

    Celona, L., E-mail: celona@lns.infn.it; Gammino, S.; Mascali, D. [Istituto Nazionale di Fisica Nucleare—Laboratori Nazionali del Sud, Via S. Sofia 62, 95123 Catania (Italy)

    2016-02-15

    One of the limiting factors for the full understanding of Electron Cyclotron Resonance Ion Sources (ECRISs) fundamental mechanisms consists of few types of diagnostic tools so far available for such compact machines. Microwave-to-plasma coupling optimisation, new methods of density overboost provided by plasma wave generation, and magnetostatic field tailoring for generating a proper electron energy distribution function, suitable for optimal ion beams formation, require diagnostic tools spanning across the entire electromagnetic spectrum from microwave interferometry to X-ray spectroscopy; these methods are going to be implemented including high resolution and spatially resolved X-ray spectroscopy made by quasi-optical methods (pin-hole cameras). The ion confinement optimisation also requires a complete control of cold electrons displacement, which can be performed by optical emission spectroscopy. Several diagnostic tools have been recently developed at INFN-LNS, including “volume-integrated” X-ray spectroscopy in low energy domain (2-30 keV, by using silicon drift detectors) or high energy regime (>30 keV, by using high purity germanium detectors). For the direct detection of the spatially resolved spectral distribution of X-rays produced by the electronic motion, a “pin-hole camera” has been developed also taking profit from previous experiences in the ECRIS field. The paper will give an overview of INFN-LNS strategy in terms of new microwave-to-plasma coupling schemes and advanced diagnostics supporting the design of new ion sources and for optimizing the performances of the existing ones, with the goal of a microwave-absorption oriented design of future machines.

  1. High density plasmas and new diagnostics: An overview (invited).

    Science.gov (United States)

    Celona, L; Gammino, S; Mascali, D

    2016-02-01

    One of the limiting factors for the full understanding of Electron Cyclotron Resonance Ion Sources (ECRISs) fundamental mechanisms consists of few types of diagnostic tools so far available for such compact machines. Microwave-to-plasma coupling optimisation, new methods of density overboost provided by plasma wave generation, and magnetostatic field tailoring for generating a proper electron energy distribution function, suitable for optimal ion beams formation, require diagnostic tools spanning across the entire electromagnetic spectrum from microwave interferometry to X-ray spectroscopy; these methods are going to be implemented including high resolution and spatially resolved X-ray spectroscopy made by quasi-optical methods (pin-hole cameras). The ion confinement optimisation also requires a complete control of cold electrons displacement, which can be performed by optical emission spectroscopy. Several diagnostic tools have been recently developed at INFN-LNS, including "volume-integrated" X-ray spectroscopy in low energy domain (2-30 keV, by using silicon drift detectors) or high energy regime (>30 keV, by using high purity germanium detectors). For the direct detection of the spatially resolved spectral distribution of X-rays produced by the electronic motion, a "pin-hole camera" has been developed also taking profit from previous experiences in the ECRIS field. The paper will give an overview of INFN-LNS strategy in terms of new microwave-to-plasma coupling schemes and advanced diagnostics supporting the design of new ion sources and for optimizing the performances of the existing ones, with the goal of a microwave-absorption oriented design of future machines.

  2. Ultra-high Density SNParray in Neuroblastoma Molecular Diagnostics

    Directory of Open Access Journals (Sweden)

    Inge M. Ambros

    2014-08-01

    Full Text Available Neuroblastoma serves as a paradigm for applying tumor genomic data for determining patient prognosis and thus for treatment allocation. MYCN status, i.e. amplified vs. non-amplified, was one of the very first biomarkers in oncology to discriminate aggressive from less aggressive or even favorable clinical courses of neuroblastoma. However, MYCN amplification is by far not the only genetic change associated with unfavorable clinical courses: so called segmental chromosomal aberrations, i.e. gains or losses of chromosomal fragments, can also indicate tumor aggressiveness. The clinical use of these genomic aberrations has, however, been hampered for many years by methodical and interpretational problems. Only after reaching worldwide consensus on markers, methodology, and data interpretation, information on SCAs has recently been implemented in clinical studies. Now, a number of collaborative studies within COG, GPOH and SIOPEN use genomic information to stratify therapy for patients with localized and metastatic disease. Recently, new types of DNA based aberrations influencing the clinical behavior of neuroblastomas have been described. Deletions or mutations of genes like ATRX and a phenomenon referred to as chromothripsis are all assumed to correlate with an unfavorable clinical behavior. However, these genomic aberrations need to be scrutinized in larger studies applying the most appropriate techniques. Single nucleotide polymorphism (SNP arrays have proven successful in deciphering genomic aberrations of cancer cells; these techniques, however, are usually not applied in the daily routine. Here, we present an ultra-high density (UHD SNParray technique which is, because of its high specificity and sensitivity and the combined copy number and allele information, highly appropriate for the genomic diagnosis of neuroblastoma and other malignancies.

  3. Double-lumen endotracheal tube positioning: Bag compliance Vs. fiberoptic bronchoscopy

    Directory of Open Access Journals (Sweden)

    MR Hoseini

    2012-11-01

    Full Text Available Background: Lung separation is the basis of thoracic anesthesia, which is performed by different instruments. Checking probable malpositioning of tracheal tube needs fiberoptic bronchoscopy. The aim of this study was to compare respirator suggested compliance with fiberoptic findings in detecting major tracheal tube malpositioning.Methods: A total of 256 patients undergoing thoracic surgery with double-lumen tracheal tube insertion in Imam Khomeini Hospital, Tehran, Iran, during 2010-11 were divided into three groups (n=86. We used left-sided double-lumen tube (DLT for left or right-sided surgeries (groups 1 and 2, and right-sided DLT for left-sided surgeries (group 3. The position of the tubes was evaluated and compared using bag compliance versus fiberoptic bronchoscopy.Results: The mean age of the study population was 44.7±13.4 (16-73 years, while 155 (59.9% were male. The sensitivity, specificity, positive and negative predictive values, and the accuracy of bag compliance test for left-sided DLT in supine position were 40% (95% CI: 20-60%, 99% (95% CI: 96-99%, 84% (95% CI: 54-94% 92% (95% CI: 88-95% and 92% (95% CI: 87-95%, respectively. The above-mentioned variables for lateral decubitus position respectively were 27%, 98%, 76%, 89%, and 88%. Malpositioning was more prevalent in right-sided DLTs (P=0.02.Conclusion: Based on the results of this study, and the high specificity, positive predictive value, and accuracy of bag compliance test, its use is encouraged as an alternative to fiberoptic bronchoscopy for checking DLT position, specially, in emergent surgeries or when fiberoptic bronchoscopy is unreachable due to lack of expertise or personnel.

  4. Plasma behaviour at high beta and high density in the Madison Symmetric Torus RFP

    Energy Technology Data Exchange (ETDEWEB)

    Wyman, M. [University of Wisconsin, Madison; Chapman, B. E. [University of Wisconsin, Madison; Ahn, J. W. [University of Wisconsin, Madison; Almagri, A. F. [University of Wisconsin, Madison; Anderson, J. [University of Wisconsin, Madison; Bonomo, F. [Consorzio RFX, Italy; Bower, D L [University of California, Los Angeles; Combs, Stephen Kirk [ORNL; Craig, D. [University of Wisconsin, Madison; Foust, Charles R [ORNL

    2009-01-01

    Pellet fuelling of improved confinement Madison Symmetric Torus (MST) plasmas has resulted in high density and high plasma beta. The density in improved confinement discharges has been increased fourfold, and a record plasma beta (beta(tot) = 26%) for the improved confinement reversed-field pinch (RFP) has been achieved. At higher beta, a new regime for instabilities is accessed in which local interchange and global tearing instabilities are calculated to be linearly unstable, but experimentally, no severe effect, e. g., a disruption, is observed. The tearing instability, normally driven by the current gradient, is driven by the pressure gradient in this case, and there are indications of increased energy transport ( as compared with low-density improved confinement). Pellet fuelling is also compared with enhanced edge fuelling of standard confinement RFP discharges for the purpose of searching for a density limit in MST. In standard-confinement discharges, pellet fuelling peaks the density profile where edge fuelling cannot, but transport appears unchanged. For a limited range of plasma current, MST discharges with edge fuelling are constrained to a maximum density corresponding to the Greenwald limit. This limit is surpassed in pellet-fuelled improved confinement discharges.

  5. Fundamental properties of high-quality carbon nanofoam: from low to high density

    Directory of Open Access Journals (Sweden)

    Natalie Frese

    2016-12-01

    Full Text Available Highly uniform samples of carbon nanofoam from hydrothermal sucrose carbonization were studied by helium ion microscopy (HIM, X-ray photoelectron spectroscopy (XPS, and Raman spectroscopy. Foams with different densities were produced by changing the process temperature in the autoclave reactor. This work illustrates how the geometrical structure, electron core levels, and the vibrational signatures change when the density of the foams is varied. We find that the low-density foams have very uniform structure consisting of micropearls with ≈2–3 μm average diameter. Higher density foams contain larger-sized micropearls (≈6–9 μm diameter which often coalesced to form nonspherical μm-sized units. Both, low- and high-density foams are comprised of predominantly sp2-type carbon. The higher density foams, however, show an advanced graphitization degree and a stronger sp3-type electronic contribution, related to the inclusion of sp3 connections in their surface network.

  6. High energy density interpenetrating networks from ionic networks and silicone

    DEFF Research Database (Denmark)

    Yu, Liyun; Madsen, Frederikke Bahrt; Hvilsted, Søren;

    2015-01-01

    The energy density of dielectric elastomers (DEs) is sought increased for better exploitation of the DE technology since an increased energy density means that the driving voltage for a certain strain can be lowered in actuation mode or alternatively that more energy can be harvested in generator...

  7. Matter composition at high density by effective scaled lagrangian

    Energy Technology Data Exchange (ETDEWEB)

    Hyun, Chang Ho; Min, Dong Pil [Dept. of Physics, Seoul National Univ., Seoul (Korea, Republic of)

    1998-06-01

    We investigate the matter composition at around the neutron star densities with a model lagrangian satisfying Brown-Rho scaling law. We calculate the neutron star properties such as maximum mass, radius, hyperon compositions and central density. We compare our results with those of Walecka model. (orig.)

  8. Calvarial reconstruction using high-density porous polyethylene cranial hemispheres

    Directory of Open Access Journals (Sweden)

    Nitin J Mokal

    2011-01-01

    Full Text Available Aims: Cranial vault reconstruction can be performed with a variety of autologous or alloplastic materials. We describe our experience using high-density porous polyethylene (HDPE cranial hemisphere for cosmetic and functional restoration of skull defects. The porous nature of the implant allows soft tissue ingrowth, which decreases the incidence of infection. Hence, it can be used in proximity to paranasal sinuses and where previous alloplastic cranioplasties have failed due to implant infection. Materials and Methods: We used the HDPE implant in seven patients over a three-year period for reconstruction of moderate to large cranial defects. Two patients had composite defects, which required additional soft tissue in the form of free flap and tissue expansion. Results: In our series, decompressive craniectomy following trauma was the commonest aetiology and all defects were located in the fronto-parieto-temporal region. The defect size was 10 cm on average in the largest diameter. All patients had good post-operative cranial contour and we encountered no infections, implant exposure or implant migration. Conclusions: Our results indicate that the biocompatibility and flexibility of the HDPE cranial hemisphere implant make it an excellent alternative to existing methods of calvarial reconstruction.

  9. Stability of discoidal high-density lipoprotein particles

    Science.gov (United States)

    Maleki, Mohsen; Fried, Eliot

    Motivated by experimental and numerical studies revealing that discoidal high-density lipoprotein (HDL) particles may adopt flat elliptical and nonplanar saddle-like configurations, it is hypothesized that these might represent stabilized configurations of initially unstable flat circular particles. A variational description is developed to explore the stability of a flat circular discoidal HDL particle. While the lipid bilayer is modeled as two-dimensional fluid film endowed with surface tension and bending elasticity, the apoA-I belt is modeled as one-dimensional inextensible twist-free chain endowed with bending elasticity. Stability is investigated using the second variation of the underlying energy functional. Various planar and nonplanar instability modes are predicted and corresponding nondimensional critical values of salient dimensionless parameters are obtained. The results predict that the first planar and nonplanar unstable modes occur due to in-plane elliptical and transverse saddle-like perturbations. Based on available data, detailed stability diagrams indicate the range of input parameters for which a flat circular discoidal HDL particle is linearly stable or unstable.

  10. High-density matter: current status and future challenges

    Science.gov (United States)

    Stone, J. R.

    2015-05-01

    There are many fascinating processes in the Universe which we observe in more and more in detail thanks to increasingly sophisticated technology. One of the most interesting phenomena is the life cycle of stars, their birth, evolution and death. If the stars are massive enough, they end their lives in the core-collapse supernova explosion, the one of the most violent events in the Universe. As the result, the densest objects in the Universe, neutron stars and/or black holes are created. Naturally, the physical basis of these events should be understood in line with observation. The current status of our knowledge of processes in the life of stars is far from adequate for their true understanding. We show that although many models have been constructed their detailed ability to describe observations is limited or non-existent. Furthermore the general failure of all models means that we cannot tell which are heading in the right direction. A possible way forward in modeling of high-density matter is outlined, exemplified by the quark-meson-coupling model (QMC). This model has a natural explanation for the saturation of nuclear forces and depends on very few adjustable parameters, strongly constrained by the underlying physics. Latest QMC results for compact objects and finite nuclei are presented.

  11. Properties of Raphia Palm Interspersed Fibre Filled High Density Polyethylene

    Directory of Open Access Journals (Sweden)

    Henry C. Obasi

    2013-01-01

    Full Text Available Blends of nonbiodegradable and biodegradable polymers can promote a reduction in the volume of plastic waste when they undergo partial degradation. In this study, properties of raphia palm interspersed fibre (RPIF filled high density polyethylene (HDPE have been investigated at different levels of filler loadings, 0 to 60 wt.%. Maleic anhydride-graft polyethylene was used as a compatibilizer. Raphia palm interspersed fibre was prepared by grinding and sieved to a particle size of 150 µm. HDPE blends were prepared in a corotating twin screw extruder. Results showed that the tensile strength and elongation at break of the blends decreased with increase in RPI loadings and addition of MA-g-PE was found to improve these properties. However, the Young’s modulus increased with increase in the amount of RPI into HDPE and compatibilization further increased the Young’s modulus. The water absorption indices and weight loss for RPI/HDPE composites were found to increase with RPI loadings but were decreased on addition of MA-g-PE.

  12. Anti-Viral Antibody Profiling by High Density Protein Arrays

    Science.gov (United States)

    Bian, Xiaofang; Wiktor, Peter; Kahn, Peter; Brunner, Al; Khela, Amritpal; Karthikeyan, Kailash; Barker, Kristi; Yu, Xiaobo; Magee, Mitch; Wasserfall, Clive H.; Gibson, David; Rooney, Madeleine E; Qiu, Ji; LaBaer, Joshua

    2015-01-01

    Viral infections elicit anti-viral antibodies and have been associated with various chronic diseases. Detection of these antibodies can facilitate diagnosis, treatment of infection and understanding of the mechanisms of virus associated diseases. In this work, we assayed anti-viral antibodies using a novel high density-nucleic acid programmable protein array (HD-NAPPA) platform. Individual viral proteins were expressed in situ directly from plasmids encoding proteins in an array of microscopic reaction chambers. Quality of protein display and serum response was assured by comparing intra- and inter- array correlation within or between printing batches with average correlation coefficients of 0.91 and 0.96, respectively. HD-NAPPA showed higher signal to background (S/B) ratio compared with standard NAPPA on planar glass slides and ELISA. Antibody responses to 761 antigens from 25 different viruses were profiled among patients with juvenile idiopathic arthritis (JIA) and type 1 diabetes (T1D). Common as well as unique antibody reactivity patterns were detected between patients and healthy controls. We believe HD-viral-NAPPA will enable the study of host-pathogen interactions at unprecedented dimensions and elucidate the role of pathogen infections in disease development. PMID:25758251

  13. High-density matter: current status and future challenges

    Directory of Open Access Journals (Sweden)

    Stone J. R.

    2015-01-01

    Full Text Available There are many fascinating processes in the Universe which we observe in more and more in detail thanks to increasingly sophisticated technology. One of the most interesting phenomena is the life cycle of stars, their birth, evolution and death. If the stars are massive enough, they end their lives in the core-collapse supernova explosion, the one of the most violent events in the Universe. As the result, the densest objects in the Universe, neutron stars and/or black holes are created. Naturally, the physical basis of these events should be understood in line with observation. The current status of our knowledge of processes in the life of stars is far from adequate for their true understanding. We show that although many models have been constructed their detailed ability to describe observations is limited or non-existent. Furthermore the general failure of all models means that we cannot tell which are heading in the right direction. A possible way forward in modeling of high-density matter is outlined, exemplified by the quark-meson-coupling model (QMC. This model has a natural explanation for the saturation of nuclear forces and depends on very few adjustable parameters, strongly constrained by the underlying physics. Latest QMC results for compact objects and finite nuclei are presented.

  14. Effect of substrates on crystallization of high density polyethylene

    Institute of Scientific and Technical Information of China (English)

    范毓润; 林渊; 阮绵照

    2008-01-01

    The experimental observations about remarkable influence of the substrates on the isothermal crystallization rate of a high density polyethylene(HDPE) were presented.Two methods were used to characterize the crystallization rate:the change of turbidity of the HDPE specimen and the changes of the complex viscosity and storage modulus measured by a rotational rheometer,which gave consistent results showing that the isothermal crystallization rate decreased in sequence as the specimen contacted with aluminum,brass and stainless steel plates,respectively.As to the dominant influence factor,the chemical composition of the substrates can be excluded via insulating the plate by an aluminum foil.Instead,we propose the plate’s ability of removing the latent heat of crystallization from the specimen.Rheological measurement is sensitive to the crystallization process.The colloid like model proposed by BOUTAHAR et al for the crystallization of HDPE gives reasonable predictions of the crystallized fraction from the measured storage modulus.

  15. Upgrading of biorenewables to high energy density fuels

    Energy Technology Data Exchange (ETDEWEB)

    Gordon, John C [Los Alamos National Laboratory; Batista, Enrique R [Los Alamos National Laboratory; Chen, Weizhong [Los Alamos National Laboratory; Currier, Robert P [Los Alamos National Laboratory; Dirmyer, Matthew R [Los Alamos National Laboratory; John, Kevin D [Los Alamos National Laboratory; Kim, Jin K [Los Alamos National Laboratory; Keith, Jason [Los Alamos National Laboratory; Martin, Richard L [Los Alamos National Laboratory; Pierpont, Aaron W [Los Alamos National Laboratory; Silks Ill, L. A. " " Pete [Los Alamos National Laboratory; Smythe, Mathan C [Los Alamos National Laboratory; Sutton, Andrew D [Los Alamos National Laboratory; Taw, Felicia L [Los Alamos National Laboratory; Trovitch, Ryan J [Los Alamos National Laboratory; Vasudevan, Kalyan V [Los Alamos National Laboratory; Waidmann, Christopher R [Los Alamos National Laboratory; Wu, Ruilian [Los Alamos National Laboratory; Baker, R. Thomas [UNIV OF OTTAWWA; Schlaf, Marcel [UNIV OF GUELPH

    2010-12-07

    According to a recent report, lignocellulose is the most abundant renewable biological resource on earth, with an annual production of {approx} 200 x 10{sup 9} tons. Conversion of lignocellulosics derived from wood, agricultural wastes, and woody grasses into liquid fuels and value-added chemical feedstocks is an active area of research that has seen an explosion of effort due to the need to replace petroleum based sources. The carbohydrates D-glucose (C{sub 6}), L-arabinose (C{sub 5}), and D-xylose (C{sub 5}) are readily obtained from the hydrolysis of lignocellulose and constitute the most abundant renewable organic carbon source on the planet. Because they are naturally produced on such a large scale, these sugars have the greatest potential to displace petrochemical derived transportation fuel. Recent efforts in our laboratories aimed towards the production of high energy density transportation fuels from carbohydrates have been structured around the parameters of selective carbohydrate carbon chain extension chemistries, low reaction temperatures, and the desired use of water or neat substrate as the solvent. Some of our efforts in this regard will be presented.

  16. Nuclear isomers as ultra-high-energy-density materials

    Science.gov (United States)

    Poppe, C. H.; Weiss, M. S.; Anderson, J. D.

    1992-09-01

    A major energy advance could result if the enormous potential of nuclear energy storage could be tapped without the penalty of radioactive by-products. Recent research has uncovered a new method for nuclear energy storage with high energy density and no residual radioactivity. Nuclear isomers are metastable states of atomic nuclei which release their energy in a prompt burst of electromagnetic radiation; in many cases the product remaining after decay of isomer is stable and no activity is produced by the electromagnetic decay. Two kinds of nuclear isomers are known: spin isomers and shape isomers. The former lacks a release mechanism. Theory has predicted the existence of shape isomers in the mass range around mercury and gold where decay by fission is prohibited. Experiments on the existence of fissionless shape isomers have resulted in evidence for 27 different shape isomers in isotopes of mercury, lead, and thallium. Three potential candidates for release mechanisms have been identified to date: neutron catalysis (Hf- 178), laser-electron-nuclear coupling (Th-229), and Stark-shift-induced mixing (speculative). Ways of producing nonfissioning shape isomers are discussed.

  17. High Density Lipoprotein: A Therapeutic Target in Type 2 Diabetes

    Directory of Open Access Journals (Sweden)

    Philip J. Barter

    2013-09-01

    Full Text Available High density lipoproteins (HDLs have a number of properties that have the potential to inhibit the development of atherosclerosis and thus reduce the risk of having a cardiovascular event. These protective effects of HDLs may be reduced in patients with type 2 diabetes, a condition in which the concentration of HDL cholesterol is frequently low. In addition to their potential cardioprotective properties, HDLs also increase the uptake of glucose by skeletal muscle and stimulate the synthesis and secretion of insulin from pancreatic β cells and may thus have a beneficial effect on glycemic control. This raises the possibility that a low HDL concentration in type 2 diabetes may contribute to a worsening of diabetic control. Thus, there is a double case for targeting HDLs in patients with type 2 diabetes: to reduce cardiovascular risk and also to improve glycemic control. Approaches to raising HDL levels include lifestyle factors such as weight reduction, increased physical activity and stopping smoking. There is an ongoing search for HDL-raising drugs as agents to use in patients with type 2 diabetes in whom the HDL level remains low despite lifestyle interventions.

  18. High-density lipoprotein endocytosis in endothelial cells

    Institute of Scientific and Technical Information of China (English)

    Stefanie; Fruhwürth; Margit; Pavelka; Robert; Bittman; Werner; J; Kovacs; Katharina; M; Walter; Clemens; Rhrl; Herbert; Stangl

    2013-01-01

    AIM: To describe the way stations of high-density lipoprotein(HDL) uptake and its lipid exchange in endothelial cells in vitro and in vivo. METHODS: A combination of fluorescence microscopy using novel fluorescent cholesterol surrogates and electron microscopy was used to analyze HDL endocytosis in great detail in primary human endothelial cells. Further, HDL uptake was quantified using radio-labeled HDL particles. To validate the in vitro findings mice were injected with fluorescently labeled HDL and particle uptake in the liver was analyzed using fluorescencemicroscopy. RESULTS: HDL uptake occurred via clathrin-coated pits, tubular endosomes and multivesicular bodies in human umbilical vein endothelial cells. During uptake and resecretion, HDL-derived cholesterol was exchanged at a faster rate than cholesteryl oleate, resembling the HDL particle pathway seen in hepatic cells. In addition, lysosomes were not involved in this process and thus HDL degradation was not detectable. In vivo, we found HDL mainly localized in mouse hepatic endothelial cells. HDL was not detected in parenchymal liver cells, indicating that lipid transfer from HDL to hepatocytes occurs primarily via scavenger receptor, class B, type Ⅰ mediated selective uptake without concomitant HDL endocytosis. CONCLUSION: HDL endocytosis occurs via clathrincoated pits, tubular endosomes and multivesicular bodies in human endothelial cells. Mouse endothelial cells showed a similar HDL uptake pattern in vivo indicating that the endothelium is one major site of HDL endocytosis and transcytosis.

  19. Crystallographic alignment of high-density gallium nitride nanowire arrays.

    Science.gov (United States)

    Kuykendall, Tevye; Pauzauskie, Peter J; Zhang, Yanfeng; Goldberger, Joshua; Sirbuly, Donald; Denlinger, Jonathan; Yang, Peidong

    2004-08-01

    Single-crystalline, one-dimensional semiconductor nanostructures are considered to be one of the critical building blocks for nanoscale optoelectronics. Elucidation of the vapour-liquid-solid growth mechanism has already enabled precise control over nanowire position and size, yet to date, no reports have demonstrated the ability to choose from different crystallographic growth directions of a nanowire array. Control over the nanowire growth direction is extremely desirable, in that anisotropic parameters such as thermal and electrical conductivity, index of refraction, piezoelectric polarization, and bandgap may be used to tune the physical properties of nanowires made from a given material. Here we demonstrate the use of metal-organic chemical vapour deposition (MOCVD) and appropriate substrate selection to control the crystallographic growth directions of high-density arrays of gallium nitride nanowires with distinct geometric and physical properties. Epitaxial growth of wurtzite gallium nitride on (100) gamma-LiAlO(2) and (111) MgO single-crystal substrates resulted in the selective growth of nanowires in the orthogonal [1\\[Evec]0] and [001] directions, exhibiting triangular and hexagonal cross-sections and drastically different optical emission. The MOCVD process is entirely compatible with the current GaN thin-film technology, which would lead to easy scale-up and device integration.

  20. Survival of charged rho condensation at high temperature and density

    CERN Document Server

    Liu, Hao; Huang, Mei

    2015-01-01

    The charged vector $\\rho$ mesons in the presence of external magnetic fields at finite temperature $T$ and chemical potential $\\mu$ have been investigated in the framework of the Nambu--Jona-Lasinio model. We compute the masses of charged $\\rho$ mesons numerically as a function of the magnetic field for different values of temperature and chemical potential. The self-energy of the $\\rho$ meson contains the quark-loop contribution, i.e. the leading order contribution in $1/N_c$ expansion. The charged $\\rho$ meson mass decreases with the magnetic field and drops to zero at a critical magnetic field $eB_c$, which means that the charged vector meson condensation, i.e. the electromagnetic superconductor can be induced above the critical magnetic field. Surprisingly, it is found that the charged $\\rho$ condensation can even survive at high temperature and density. At zero temperature, the critical magnetic field just increases slightly with the chemical potential, which indicates that the charged $\\rho$ condensatio...

  1. Low fasting low high-density lipoprotein and postprandial lipemia

    Directory of Open Access Journals (Sweden)

    Sorodila Konstandina

    2004-07-01

    Full Text Available Abstract Background Low levels of high density lipoprotein (HDL cholesterol and disturbed postprandial lipemia are associated with coronary heart disease. In the present study, we evaluated the variation of triglyceride (TG postprandially in respect to serum HDL cholesterol levels. Results Fifty two Greek men were divided into 2 main groups: a the low HDL group (HDL p = 0.002. The low HDL group had significantly higher TG at 4, 6 and 8 h postprandially compared to the controls (p = 0.006, p = 0.002, and p p = 0.017 compared to the matched-control group. ROC analysis showed that fasting TG ≥ 121 mg/dl have 100% sensitivity and 81% specificity for an abnormal TG response (auc = 0.962, p Conclusions The delayed TG clearance postprandially seems to result in low HDL cholesterol even in subjects with low fasting TG. The fasting TG > 121 mg/dl are predictable for abnormal response to fatty meal.

  2. High-density lipoprotein (HDL) metabolism and bone mass.

    Science.gov (United States)

    Papachristou, Nicholaos I; Blair, Harry C; Kypreos, Kyriakos E; Papachristou, Dionysios J

    2017-05-01

    It is well appreciated that high-density lipoprotein (HDL) and bone physiology and pathology are tightly linked. Studies, primarily in mouse models, have shown that dysfunctional and/or disturbed HDL can affect bone mass through many different ways. Specifically, reduced HDL levels have been associated with the development of an inflammatory microenvironment that affects the differentiation and function of osteoblasts. In addition, perturbation in metabolic pathways of HDL favors adipoblastic differentiation and restrains osteoblastic differentiation through, among others, the modification of specific bone-related chemokines and signaling cascades. Increased bone marrow adiposity also deteriorates bone osteoblastic function and thus bone synthesis, leading to reduced bone mass. In this review, we present the current knowledge and the future directions with regard to the HDL-bone mass connection. Unraveling the molecular phenomena that underline this connection will promote the deeper understanding of the pathophysiology of bone-related pathologies, such as osteoporosis or bone metastasis, and pave the way toward the development of novel and more effective therapies against these conditions. © 2017 Society for Endocrinology.

  3. Preface to Special Topic: High-Energy Density Laboratory Astrophysics

    Energy Technology Data Exchange (ETDEWEB)

    Glenzer, Siegfried H.; /SLAC

    2017-04-01

    In the 1990s, when the large inertial confinement fusion facilities in the United States became accessible for discovery-class research, physicists soon realized that the combination of these energetic drivers with precision plasmas diagnostics would allow the unprecedented experimental study of astrophysical problems. These facilities routinely produce states of matter in the high-energy density physics regime, i.e., pressures above a million atmospheres, 1011 J/m3, and employ a suite of temporally and spatially resolving imaging and scattering measurements that were originally developed to understand the behavior of inertial confinement fusion plasmas. These capabilities bring to the field of astrophysics critical experimental tests of simulations in relevant regimes that are far from the conditions that can otherwise be routinely produced on earth.5 These astrophysical motivated studies are now finding their way into the laboratory plasma community. Further, laboratory astrophysics helped to motivate the development of new precision experimental capabilities; the latest being the world-class Linac Coherent Light Source (LCLS) x-ray laser at the Matter in Extreme Conditions instrument at Stanford that is dedicated to fundamental research.

  4. Iatrogenic severe depression of high-density lipoprotein cholesterol.

    Science.gov (United States)

    Mymin, D; Dembinski, T; Friesen, M H

    2009-07-01

    The authors present 5 cases of paradoxical depression of high-density lipoprotein (HDL) cholesterol induced by fibrate drugs. In a 24-month review of all cases seen in one physician's practice at the Winnipeg Health Sciences Centre Lipid Clinic, 492 patients made a total of 1187 visits. Sixty-eight of them were given a fibrate drug (14%). Ten patients had HDL cholesterol levels that were less than 0.5 mmol/L (2%), and of these, 5 cases were due to exposure to fenofibrate (1%). These 5 cases comprised 7.4% of the 68 patients who were given any fibrate drug during that period. Mean levels were as follows: HDL cholesterol on fenofibrate 0.27, off fenofibrate 1.0 mmol/L and apo A1 on fenofibrate 0.41, off fenofibrate 1.17 g/L. A literature review revealed documented cases in 37 patients involving fibrates alone or in combination with other drugs known to cause decreased HDL cholesterol levels. In 13 patients, exposure was to fibrate therapy alone; in those exposed to combinations, the effect was clearly attributable to fibrates in 9; in 14, the nonfibrates (mostly rosiglitazone) were the attributable drugs; and in 1, it was impossible to tell. Thus, fibrate therapy should always be suspected as a cause of profoundly depressed HDL cholesterol.

  5. Properties of recycled high density polyethylene and coffee dregs composites

    Directory of Open Access Journals (Sweden)

    Sibele Piedade Cestari

    2013-01-01

    Full Text Available Composites of recycled high density polyethylene (HDPE-R and coffee dregs (COFD were elaborated. The blends were made at the proportions of 100-0, 90-10, 80-20, 70-30, 60-40, 50-50 and 40-60% polymer-filler ratio. The materials were evaluated through scanning electron microscopy (SEM, differential scanning calorimetry (DSC, thermogravimetry/derivative thermogravimetry (TGA, and compressive resistance test. The compounding was done using a two-stage co-kneader system extruder, and then cylindrical specimens were injection molded. All composites had a fine dispersion of the COFD into the polymeric matrix. The composites degraded in two steps. The first one was in a temperature lower than the neat HDPE, but higher than the average processing temperature of the polymer. The melting temperature and the degree of crystallinity of the composites resulted similar to the neat HDPE ones. The compressive moduli of the composites resulted similar to the neat polymer one. The results show that these composites have interesting properties as a building material.

  6. Improving Robotic Assembly of Planar High Energy Density Targets

    Science.gov (United States)

    Dudt, D.; Carlson, L.; Alexander, N.; Boehm, K.

    2016-10-01

    Increased quantities of planar assemblies for high energy density targets are needed with higher shot rates being implemented at facilities such as the National Ignition Facility and the Matter in Extreme Conditions station of the Linac Coherent Light Source. To meet this growing demand, robotics are used to reduce assembly time. This project studies how machine vision and force feedback systems can be used to improve the quantity and quality of planar target assemblies. Vision-guided robotics can identify and locate parts, reducing laborious manual loading of parts into precision pallets and associated teaching of locations. On-board automated inspection can measure part pickup offsets to correct part drop-off placement into target assemblies. Force feedback systems can detect pickup locations and apply consistent force to produce more uniform glue bond thickness, thus improving the performance of the targets. System designs and performance evaluations will be presented. Work supported in part by the US DOE under the Science Undergraduate Laboratory Internships Program (SULI) and ICF Target Fabrication DE-NA0001808.

  7. A system verification platform for high-density epiretinal prostheses.

    Science.gov (United States)

    Chen, Kuanfu; Lo, Yi-Kai; Yang, Zhi; Weiland, James D; Humayun, Mark S; Liu, Wentai

    2013-06-01

    Retinal prostheses have restored light perception to people worldwide who have poor or no vision as a consequence of retinal degeneration. To advance the quality of visual stimulation for retinal implant recipients, a higher number of stimulation channels is expected in the next generation retinal prostheses, which poses a great challenge to system design and verification. This paper presents a system verification platform dedicated to the development of retinal prostheses. The system includes primary processing, dual-band power and data telemetry, a high-density stimulator array, and two methods for output verification. End-to-end system validation and individual functional block characterization can be achieved with this platform through visual inspection and software analysis. Custom-built software running on the computers also provides a good way for testing new features before they are realized by the ICs. Real-time visual feedbacks through the video displays make it easy to monitor and debug the system. The characterization of the wireless telemetry and the demonstration of the visual display are reported in this paper using a 256-channel retinal prosthetic IC as an example.

  8. Liquid lithium for high power density fragmentation targets

    Science.gov (United States)

    Nolen, J. A.; Reed, C. B.; Hassanein, A.; Morrissey, D. J.; Ottarson, J. H.; Sherrill, B. M.

    2001-10-01

    Windowless liquid lithium targets for in-flight fragmentation or fission of high power heavy ion beams are being developed for the U.S. RIA project. With uranium beam power of 100 kW and a beam spot diameter of 1 mm the power density in the target is over 1 MW/cm3. Thermal analysis for this example indicates a very low peak temperature for the lithium when flowing at a linear velocity of 10 m/s. A vacuum test chamber is under construction at Argonne at an existing liquid lithium facility to demonstrate a 2 cm thick windowless target. As a first step towards using liquid lithium target technology at a nuclear physics fragmentation facility, a lower power target is being constructed for use at the NSCL. This target will use beryllium windows with flowing lithium. It is designed for beams between oxygen and calcium with beam power above 3 kW. The tapered beryllium windows are each 1 mm thick for the calcium beams and 7 mm thick for the oxygen beams. The lithium is 5 mm thick. This gives an overall target thickness ranging from about 1 g/cm2 to 3 g/cm2 which is adjusted by moving the target vertically. The designs of these targets and the status of the prototypes will be discussed.

  9. High density 3D printed microfluidic valves, pumps, and multiplexers.

    Science.gov (United States)

    Gong, Hua; Woolley, Adam T; Nordin, Gregory P

    2016-07-07

    In this paper we demonstrate that 3D printing with a digital light processor stereolithographic (DLP-SLA) 3D printer can be used to create high density microfluidic devices with active components such as valves and pumps. Leveraging our previous work on optical formulation of inexpensive resins (RSC Adv., 2015, 5, 106621), we demonstrate valves with only 10% of the volume of our original 3D printed valves (Biomicrofluidics, 2015, 9, 016501), which were already the smallest that have been reported. Moreover, we show that incorporation of a thermal initiator in the resin formulation along with a post-print bake can dramatically improve the durability of 3D printed valves up to 1 million actuations. Using two valves and a valve-like displacement chamber (DC), we also create compact 3D printed pumps. With 5-phase actuation and a 15 ms phase interval, we obtain pump flow rates as high as 40 μL min(-1). We also characterize maximum pump back pressure (i.e., maximum pressure the pump can work against), maximum flow rate (flow rate when there is zero back pressure), and flow rate as a function of the height of the pump outlet. We further demonstrate combining 5 valves and one DC to create a 3-to-2 multiplexer with integrated pump. In addition to serial multiplexing, we also show that the device can operate as a mixer. Importantly, we illustrate the rapid fabrication and test cycles that 3D printing makes possible by implementing a new multiplexer design to improve mixing, and fabricate and test it within one day.

  10. Experimental study of high density foods for the Space Operations Center

    Science.gov (United States)

    Ahmed, S. M.

    1981-01-01

    The experimental study of high density foods for the Space Operations Center is described. A sensory evaluation of the high density foods was conducted first to test the acceptability of the products. A shelf-life study of the high density foods was also conducted for three different time lengths at three different temperatures. The nutritional analysis of the high density foods is at present incomplete.

  11. High Density Nano-Electrode Array for Radiation Detection

    Energy Technology Data Exchange (ETDEWEB)

    Mano Misra

    2010-05-07

    Bulk single crystals of Cd1-xZnxTe (x=0.04 to x=0.2) compound semiconductor is used for room temperature radiation detection. The production of large volume of Cd1-xZnxTe with low defect density is expensive. As a result there is a growing research interest in the production of nanostructured compound semiconductors such as Cd1-xZnxTe in an electrochemical route. In this investigation, Cd1-xZnxTe ternary compound semiconductor, referred as CZT, was electrodeposited in the form of nanowires onto a TiO2 nanotubular template from propylene carbonate as the non-aqueous electrolyte, using a pulse-reverse electrodeposition process at 130 ºC. The template acted as a support in growing ordered nanowire of CZT which acts as a one dimensional conductor. Cyclic Voltammogram (CV) studies were conducted in determining the potentials for the growth of nanowires of uniform stoichiometry. The morphologies and composition of CZT were characterized by using SEM, TEM and XRD. The STEM mapping carried out on the nanowires showed the uniform distribution of Cd, Zn and Te elements. TEM image showed that the nanowires were polycrystalline in nature. The Mott-Schottky analysis carried on the nanowires showed that the nanowires were a p-type semiconductor. The carrier density, band gap and resistivity of the Cd0.9Zn0.1Te nanowires were 4.29x1013 cm-3, 1.56 eV and 2.76x1011Ω-cm respectively. The high resistivity was attributed to the presence of deep defect states such as cadmium vacancies or Te antisites which were created by the anodic cycle of the pulse-reverse electrodeposition process. Stacks of series connected CZT nanowire arrays were tested with different bias potentials. The background current was in the order of tens of picoamperes. When exposed to radiation source Amerecium-241 (60 KeV, 4 μCi), the stacked CZT nanowires arrays showed sensing behavior. The sensitivity of the nanowire arrays increased as the number of stacks increased. The preliminary results indicate that the

  12. High-Density Plasma Reactors: Simulations for Design

    Science.gov (United States)

    Hash, David B.; Meyyappan, Meyya; Arnold, James O. (Technical Monitor)

    1998-01-01

    The development of improved and more efficient plasma reactors is a costly process for the semiconductor industry. Until five years ago, the Industry made most of its advancements through a trial and error approach. More recently, the role of computational modeling in the design process has increased. Both conventional computational fluid dynamics (CFD) techniques like Navier-Stokes solvers as well as particle simulation methods are used to model plasma reactor flowfields. However, since high-density plasma reactors generally operate at low gas pressures on the order of 1 to 10 mTorr, a particle simulation may be necessary because of the failure of CFD techniques to model rarefaction effects. The direct simulation Monte Carlo method is the most widely accepted and employed particle simulation tool and has previously been used to investigate plasma reactor flowfields. A plasma DSMC code is currently under development at NASA Ames Research Center with its foundation as the object-oriented parallel Cornell DSMC code, MONACO. The present investigation is a follow up of a neutral flow investigation of the effects of process parameters as well as reactor design on etch rate and etch rate uniformity. The previous work concentrated on silicon etch of a chlorine flow in a configuration typical of electron cyclotron resonance (ECR) or helical resonator type reactors. The effects of the plasma on the dissociation chemistry were modeled by making assumptions about the electron temperature and number density. The electrons or ions themselves were not simulated.The present work extends these results by simulating the charged species.The electromagnetic fields are calculated such that power deposition is modeled self-consistently. Electron impact reactions are modeled along with mechanisms for charge exchange. An bipolar diffusion assumption is made whereby electrons remain tied to the ions. However, the velocities of tile electrons are allowed to be modified during collisions

  13. High thermal power density heat transfer apparatus providing electrical isolation at high temperature using heat pipes

    Science.gov (United States)

    Morris, J. F. (Inventor)

    1985-01-01

    This invention is directed to transferring heat from an extremely high temperature source to an electrically isolated lower temperature receiver. The invention is particularly concerned with supplying thermal power to a thermionic converter from a nuclear reactor with electric isolation. Heat from a high temperature heat pipe is transferred through a vacuum or a gap filled with electrically nonconducting gas to a cooler heat pipe. If the receiver requires gratr thermal power density, geometries are used with larger heat pipe areas for transmitting and receiving energy than the area for conducting the heat to the thermionic converter. In this way the heat pipe capability for increasing thermal power densities compensates for the comparative low thermal power densities through the electrically nonconducting gap between the two heat pipes.

  14. High current density stability of ohmic contacts to silicon carbide

    Science.gov (United States)

    Downey, Brian P.

    The materials properties of SiC, such as wide bandgap, high breakdown electric field, and good thermal conductivity, make it an appealing option for high temperature and high power applications. The replacement of Si devices with SiC components could lead to a reduction in device size, weight, complexity, and cooling requirements along with an increase in device efficiency. One area of concern under high temperature or high current operation is the stability of the ohmic contacts. Ohmic contact degradation can cause an increase in parasitic resistance, which can diminish device performance. While contact studies have primarily focused on the high temperature stability of ohmic contacts to SiC, different failure mechanisms may arise under high current density stressing due to the influence of electromigration. In addition, preferential degradation may occur at the anode or cathode due to the directionality of current flow, known as a polarity effect. The failure mechanisms of ohmic contacts to p-type SiC under high current density stressing are explored. Complementary materials characterization techniques were used to analyze contact degradation, particularly the use of cross-sections prepared by focused ion beam for imaging using field emission scanning electron microscopy and elemental analysis using Auger electron spectroscopy. Initially the degradation of commonly studied Ni and Al-based contacts was investigated under continuous DC current. The contact metallization included a bond pad consisting of a TiW diffusion barrier and thick Au overlayer. The Ni contacts were found to degrade due to the growth of voids within the ohmic contact layer, which were initially produced during the high temperature Ni/SiC ohmic contact anneal. The Al-based contacts degraded due to the movement of Al from the ohmic contact layer to the surface of the Au bond pad, and the movement of Au into the ohmic contact layer from the bond pad. The inequality of Al and Au fluxes generated

  15. Miniaturized fiber-optic Michelson-type interferometric sensors

    Science.gov (United States)

    Murphy, Kent A.; Miller, William V., III; Tran, Tuan A.; Vengsarkar, Ashish M.; Claus, Richard O.

    1991-01-01

    A novel, miniaturized Michelson-type fiber-optic interferometric sensor that is relatively insensitive to temperature drifts is presented. A fused-biconical tapered coupler is cleaved immediately after the coupled length and polished down to the region of the fused cladding, but short of the interaction region. The end of one core is selectively coated with a reflective surface and is used as the reference arm; the other core serves as the sensing arm. The detection of surface acoustic waves, microdisplacements, and magnetic fields is reported. The sensor is shown to be highly stable in comparison to a classic homodyne, uncompensated Michelson interferometer, and signal-to-noise ratios of 65 dB have been obtained.

  16. Integration of high capacity materials into interdigitated mesostructured electrodes for high energy and high power density primary microbatteries

    Science.gov (United States)

    Pikul, James H.; Liu, Jinyun; Braun, Paul V.; King, William P.

    2016-05-01

    Microbatteries are increasingly important for powering electronic systems, however, the volumetric energy density of microbatteries lags behind that of conventional format batteries. This paper reports a primary microbattery with energy density 45.5 μWh cm-2 μm-1 and peak power 5300 μW cm-2 μm-1, enabled by the integration of large volume fractions of high capacity anode and cathode chemistry into porous micro-architectures. The interdigitated battery electrodes consist of a lithium metal anode and a mesoporous manganese oxide cathode. The key enabler of the high energy and power density is the integration of the high capacity manganese oxide conversion chemistry into a mesostructured high power interdigitated bicontinuous cathode architecture and an electrodeposited dense lithium metal anode. The resultant energy density is greater than previously reported three-dimensional microbatteries and is comparable to commercial conventional format lithium-based batteries.

  17. Chemically and Thermally Stable High Energy Density Silicone Composites Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Thermal energy storage systems with 300 ? 1000 kJ/kg energy density through either phase changes or chemical heat absorption are sought by NASA. This proposed effort...

  18. High-energy side-peak emission of exciton-polariton condensates in high density regime.

    Science.gov (United States)

    Horikiri, Tomoyuki; Yamaguchi, Makoto; Kamide, Kenji; Matsuo, Yasuhiro; Byrnes, Tim; Ishida, Natsuko; Löffler, Andreas; Höfling, Sven; Shikano, Yutaka; Ogawa, Tetsuo; Forchel, Alfred; Yamamoto, Yoshihisa

    2016-05-19

    In a standard semiconductor laser, electrons and holes recombine via stimulated emission to emit coherent light, in a process that is far from thermal equilibrium. Exciton-polariton condensates-sharing the same basic device structure as a semiconductor laser, consisting of quantum wells coupled to a microcavity-have been investigated primarily at densities far below the Mott density for signatures of Bose-Einstein condensation. At high densities approaching the Mott density, exciton-polariton condensates are generally thought to revert to a standard semiconductor laser, with the loss of strong coupling. Here, we report the observation of a photoluminescence sideband at high densities that cannot be accounted for by conventional semiconductor lasing. This also differs from an upper-polariton peak by the observation of the excitation power dependence in the peak-energy separation. Our interpretation as a persistent coherent electron-hole-photon coupling captures several features of this sideband, although a complete understanding of the experimental data is lacking. A full understanding of the observations should lead to a development in non-equilibrium many-body physics.

  19. Transport analysis of high radiation and high density plasmas in the ASDEX Upgrade tokamak

    Directory of Open Access Journals (Sweden)

    Casali L.

    2014-01-01

    Full Text Available Future fusion reactors, foreseen in the “European road map” such as DEMO, will operate under more demanding conditions compared to present devices. They will require high divertor and core radiation by impurity seeding to reduce heat loads on divertor target plates. In addition, DEMO will have to work at high core densities to reach adequate fusion performance. The performance of fusion reactors depends on three essential parameters: temperature, density and energy confinement time. The latter characterizes the loss rate due to both radiation and transport processes. The DEMO foreseen scenarios described above were not investigated so far, but are now addressed at the ASDEX Upgrade tokamak. In this work we present the transport analysis of such scenarios. Plasma with high radiation by impurity seeding: transport analysis taking into account the radiation distribution shows no change in transport during impurity seeding. The observed confinement improvement is an effect of higher pedestal temperatures which extend to the core via stiffness. A non coronal radiation model was developed and compared to the bolometric measurements in order to provide a reliable radiation profile for transport calculations. High density plasmas with pellets: the analysis of kinetic profiles reveals a transient phase at the start of the pellet fuelling due to a slower density build up compared to the temperature decrease. The low particle diffusion can explain the confinement behaviour.

  20. Differential analysis for high density tiling microarray data

    Directory of Open Access Journals (Sweden)

    Kapranov Philipp

    2007-09-01

    Full Text Available Abstract Background High density oligonucleotide tiling arrays are an effective and powerful platform for conducting unbiased genome-wide studies. The ab initio probe selection method employed in tiling arrays is unbiased, and thus ensures consistent sampling across coding and non-coding regions of the genome. These arrays are being increasingly used to study the associated processes of transcription, transcription factor binding, chromatin structure and their association. Studies of differential expression and/or regulation provide critical insight into the mechanics of transcription and regulation that occurs during the developmental program of a cell. The time-course experiment, which comprises an in-vivo system and the proposed analyses, is used to determine if annotated and un-annotated portions of genome manifest coordinated differential response to the induced developmental program. Results We have proposed a novel approach, based on a piece-wise function – to analyze genome-wide differential response. This enables segmentation of the response based on protein-coding and non-coding regions; for genes the methodology also partitions differential response with a 5' versus 3' versus intra-genic bias. Conclusion The algorithm built upon the framework of Significance Analysis of Microarrays, uses a generalized logic to define regions/patterns of coordinated differential change. By not adhering to the gene-centric paradigm, discordant differential expression patterns between exons and introns have been identified at a FDR of less than 12 percent. A co-localization of differential binding between RNA Polymerase II and tetra-acetylated histone has been quantified at a p-value -13. The prototype R code has been made available as supplementary material [see Additional file 1]. Additional file 1 gsam_prototypercode.zip. File archive comprising of prototype R code for gSAM implementation including readme and examples. Click here for file

  1. Differential analysis for high density tiling microarray data.

    Science.gov (United States)

    Ghosh, Srinka; Hirsch, Heather A; Sekinger, Edward A; Kapranov, Philipp; Struhl, Kevin; Gingeras, Thomas R

    2007-09-24

    High density oligonucleotide tiling arrays are an effective and powerful platform for conducting unbiased genome-wide studies. The ab initio probe selection method employed in tiling arrays is unbiased, and thus ensures consistent sampling across coding and non-coding regions of the genome. These arrays are being increasingly used to study the associated processes of transcription, transcription factor binding, chromatin structure and their association. Studies of differential expression and/or regulation provide critical insight into the mechanics of transcription and regulation that occurs during the developmental program of a cell. The time-course experiment, which comprises an in-vivo system and the proposed analyses, is used to determine if annotated and un-annotated portions of genome manifest coordinated differential response to the induced developmental program. We have proposed a novel approach, based on a piece-wise function - to analyze genome-wide differential response. This enables segmentation of the response based on protein-coding and non-coding regions; for genes the methodology also partitions differential response with a 5' versus 3' versus intra-genic bias. The algorithm built upon the framework of Significance Analysis of Microarrays, uses a generalized logic to define regions/patterns of coordinated differential change. By not adhering to the gene-centric paradigm, discordant differential expression patterns between exons and introns have been identified at a FDR of less than 12 percent. A co-localization of differential binding between RNA Polymerase II and tetra-acetylated histone has been quantified at a p-value < 0.003; it is most significant at the 5' end of genes, at a p-value < 10-13. The prototype R code has been made available as supplementary material [see Additional file 1].

  2. Atlas Pulsed Power Facility for High Energy Density Physics Experiments

    Energy Technology Data Exchange (ETDEWEB)

    Miller, R.B.; Ballard, E.O.; Barr, G.W.; Bowman, D.W.; Chochrane, J.C.; Davis, H.A.; Elizondo, J.M.; Gribble, R.F.; Griego, J.R.; Hicks, R.D.; Hinckley, W.B.; Hosack, K.W.; Nielsen, K.E.; Parker, J.V.; Parsons, M.O.; Rickets, R.L.; Salazar, H.R.; Sanchez, P.G.; Scudder, D.W.; Shapiro, C.; Thompson, M.C.; Trainor, R.J.; Valdez, G.A.; Vigil, B.N.; Watt, R.G.; Wysock, F.J.

    1999-06-07

    The Atlas facility, now under construction at Los Alamos National Laboratory (LANL), will provide a unique capability for performing high-energy-density experiments in support of weapon-physics and basic-research programs. It is intended to be an international user facility, providing opportunities for researchers from national laboratories and academic institutions around the world. Emphasizing institutions around the world. Emphasizing hydrodynamic experiments, Atlas will provide the capability for achieving steady shock pressures exceeding 10-Mbar in a volume of several cubic centimeters. In addition, the kinetic energy associated with solid liner implosion velocities exceeding 12 km/s is sufficient to drive dense, hydrodynamic targets into the ionized regime, permitting the study of complex issues associated with strongly-coupled plasmas. The primary element of Atlas is a 23-MJ capacitor bank, comprised of 96 separate Marx generators housed in 12 separate oil-filled tanks, surrounding a central target chamber. Each tank will house two, independently-removable maintenance units, with each maintenance unit consisting of four Marx modules. Each Marx module has four capacitors that can each be charged to a maximum of 60 kilovolts. When railgap switches are triggered, the marx modules erect to a maximum of 240 kV. The parallel discharge of these 96 Marx modules will deliver a 30-MA current pulse with a 4-5-{micro}s risetime to a cylindrical, imploding liner via 24 vertical, tri-plate, oil-insulated transmission lines. An experimental program for testing and certifying all Marx and transmission line components has been completed. A complete maintenance module and its associated transmission line (the First Article) are now under construction and testing. The current Atlas schedule calls for construction of the machine to be complete by August, 2000. Acceptance testing is scheduled to begin in November, 2000, leading to initial operations in January, 2001.

  3. Surface interactions involved in flashover with high density electronegative gases.

    Energy Technology Data Exchange (ETDEWEB)

    Hodge, Keith Conquest; Warne, Larry Kevin; Jorgenson, Roy Eberhardt; Wallace, Zachariah Red; Lehr, Jane Marie

    2010-01-01

    This report examines the interactions involved with flashover along a surface in high density electronegative gases. The focus is on fast ionization processes rather than the later time ionic drift or thermalization of the discharge. A kinetic simulation of the gas and surface is used to examine electron multiplication and includes gas collision, excitation and ionization, and attachment processes, gas photoionization and surface photoemission processes, as well as surface attachment. These rates are then used in a 1.5D fluid ionization wave (streamer) model to study streamer propagation with and without the surface in air and in SF6. The 1.5D model therefore includes rates for all these processes. To get a better estimate for the behavior of the radius we have studied radial expansion of the streamer in air and in SF6. The focus of the modeling is on voltage and field level changes (with and without a surface) rather than secondary effects, such as, velocities or changes in discharge path. An experiment has been set up to carry out measurements of threshold voltages, streamer velocities, and other discharge characteristics. This setup includes both electrical and photographic diagnostics (streak and framing cameras). We have observed little change in critical field levels (where avalanche multiplication sets in) in the gas alone versus with the surface. Comparisons between model calculations and experimental measurements are in agreement with this. We have examined streamer sustaining fields (field which maintains ionization wave propagation) in the gas and on the surface. Agreement of the gas levels with available literature is good and agreement between experiment and calculation is good also. Model calculations do not indicate much difference between the gas alone versus the surface levels. Experiments have identified differences in velocity between streamers on the surface and in the gas alone (the surface values being larger).

  4. High-density lipoprotein and atherosclerosis: Roles of lipid transporters

    Institute of Scientific and Technical Information of China (English)

    Yoshinari; Uehara; Keijiro; Saku

    2014-01-01

    Various previous studies have found a negative cor-relation between the risk of cardiovascular events and serum high-density lipoprotein(HDL) cholesterol levels. The reverse cholesterol transport, a pathway of choles-terol from peripheral tissue to liver which has several potent antiatherogenic properties. For instance, the particles of HDL mediate to transport cholesterol from cells in arterial tissues, particularly from atherosclerotic plaques, to the liver. Both ATP-binding cassette trans-porters(ABC) A1 and ABCG1 are membrane cholesterol transporters and have been implicated in mediating cholesterol effluxes from cells in the presence of HDL and apolipoprotein A-I, a major protein constituent of HDL. Previous studies demonstrated that ABCA1 and ABCG1 or the interaction between ABCA1 and ABCG1 exerted antiatherosclerotic effects. As a therapeutic approach for increasing HDL cholesterol levels, much focus has been placed on increasing HDL cholesterol levels as well as enhancing HDL biochemical functions. HDL therapies that use injections of reconstituted HDL, apoA-I mimetics, or full-length apoA-I have shown dramatic effectiveness. In particular, a novel apoA-I mi-metic peptide, Fukuoka University ApoA-I Mimetic Pep-tide, effectively removes cholesterol via specific ABCA1 and other transporters, such as ABCG1, and has an an-tiatherosclerotic effect by enhancing the biological func-tions of HDL without changing circulating HDL choles-terol levels. Thus, HDL-targeting therapy has significant atheroprotective potential, as it uses lipid transporter-targeting agents, and may prove to be a therapeutic tool for atherosclerotic cardiovascular diseases.

  5. Self-sustained focusing of high-density streaming plasma

    Science.gov (United States)

    Bugaev, A.; Dobrovolskiy, A.; Goncharov, A.; Gushenets, V.; Litovko, I.; Naiko, I.; Oks, E.

    2017-01-01

    We describe our observations of the transport through an electrostatic plasma lens of a wide-aperture, high-current, low energy, metal-ion plasma flow produced by a cathodic arc discharge. The lens input aperture was 80 mm, the length of the lens was 140 mm, and there were three electrostatic ring electrodes located in a magnetic field formed by permanent magnets. The lens outer electrodes were grounded and the central electrode was biased up to -3 kV. The plasma was a copper plasma with directed (streaming) ion energy 20-40 eV, and the equivalent ion current was up to several amperes depending on the potential applied to the central lens electrode. We find that when the central lens electrode is electrically floating, the current density of the plasma flow at the lens focus increases by up to 40%-50%, a result that is in good agreement with a theoretical treatment based on plasma-optical principles of magnetic insulation of electrons and equipotentialization along magnetic field lines. When the central lens electrode is biased negatively, an on-axis stream of energetic electrons is formed, which can also provide a mechanism for focusing of the plasma flow. Optical emission spectra under these conditions show an increase in intensity of lines corresponding to both copper atoms and singly charged copper ions, indicating the presence of fast electrons within the lens volume. These energetic electrons, as well as accumulating on-axis and providing ion focusing, can also assist in reducing the microdroplet component in the dense, low-temperature, metal plasma.

  6. Compensated readout for high-density MOS-gated memristor crossbar array

    KAUST Repository

    Zidan, Mohammed A.

    2015-01-01

    Leakage current is one of the main challenges facing high-density MOS-gated memristor arrays. In this study, we show that leakage current ruins the memory readout process for high-density arrays, and analyze the tradeoff between the array density and its power consumption. We propose a novel readout technique and its underlying circuitry, which is able to compensate for the transistor leakage-current effect in the high-density gated memristor array.

  7. The viscosity and density of sour gas fluids at high temperatures and high pressures

    Energy Technology Data Exchange (ETDEWEB)

    Giri, B.R.; Marriott, R.A.; Blais, P.; Clark, P.D. [Alberta Sulphur Research Ltd., Calgary, AB (Canada); Calgary Univ., AB (Canada). Dept. of Chemistry

    2010-01-15

    This poster session discussed an experiment designed to measure the viscosity and density of sour gas fluids at high temperatures and pressures. An option for disposing acid gases while enhancing the production of oil and gas fields is the re-injection of gases rich in hydrogen sulphide/carbon dioxide (H{sub 2}S/CO{sub 2}) into reservoirs up to very high pressures, but issues with respect to corrosion, compression, pumping, and transport need addressing, and the reliable high-density/high-pressure data needed to arrive at an optimum process concept and the design of pumps, compressors, and transport lines had up to this point been lacking. The experimental set up involved the use of a Vibrating Tube Densimeter and a Cambridge Viscometer. Working with toxic gases at very high pressures and obtaining highly accurate data in a wide range of conditions were two of the challenges faced during the experiment. The experiment resulted in physical property measurement systems being recalibrated and a new daily calibration routine being adopted for accuracy. The densities and viscosities of pure CO{sub 2} and sulphur dioxide (SO{sub 2}) in a wide pressure and temperature range were determined. 1 tab., 9 figs.

  8. Preparing to perform an awake fiberoptic intubation.

    LENUS (Irish Health Repository)

    Walsh, M E

    2012-02-03

    Fiberoptically guided tracheal intubation represents one of the most important advances in airway management to occur in the past thirty years. Perhaps its most important role is in management of the anticipated difficult airway. This is a situation in which the dangers of encountering the life-threatening "can\\'t intubate, can\\'t ventilate" situation can be avoided by placement of an endotracheal tube while the patient is awake. Although skill at the procedure of endoscopy is obviously necessary in this setting, these authors hold that success or failure of the technique frequently depends on the adequacy of preparation. These measures include 1) pre-operative assessment of the patient; 2) careful explanation of what lies in store; 3) "setting the stage"; 4) preparing the equipment to be used; and 5) preparing the patient (antisialogue, sedation, application of topical anesthesia to the upper airway). If these preparatory measures are carried out meticulously, the likelihood of performing a successful and comfortable awake fiberoptic tracheal intubation is greatly increased.

  9. High Current, High Density Arc Plasma as a New Source for WiPAL

    Science.gov (United States)

    Waleffe, Roger; Endrizzi, Doug; Myers, Rachel; Wallace, John; Clark, Mike; Forest, Cary; WiPAL Team

    2016-10-01

    The Wisconsin Plasma Astrophysics Lab (WiPAL) has installed a new array of nineteen plasma sources (plasma guns) on its 3 m diameter, spherical vacuum vessel. Each gun is a cylindrical, molybdenum, washer-stabilized, arc plasma source. During discharge, the guns are maintained at 1.2 kA across 100 V for 10 ms by the gun power supply establishing a high density plasma. Each plasma source is fired independently allowing for adjustable plasma parameters, with densities varying between 1018 -1019 m-3 and electron temperatures of 5-15 eV. Measurements were characterized using a 16 tip Langmuir probe. The plasma source will be used as a background plasma for the magnetized coaxial plasma gun (MCPG), the Terrestrial Reconnection Experiment (TREX), and as the plasma source for a magnetic mirror experiment. Temperature, density, and confinement results will be presented. This work is supported by the DoE and the NSF.

  10. Aspiration in children and adolescents with neurogenic dysphagia: comparison of clinical judgment and fiberoptic endoscopic evaluation of swallowing.

    Science.gov (United States)

    Beer, Sabrina; Hartlieb, Till; Müller, Arnd; Granel, Michael; Staudt, Martin

    2014-12-01

    A total of 30 children and adolescents with dysphagia due to various chronic neurological disorders were assessed for their risk of aspiration. This assessment was performed clinically by experienced speech and swallowing therapists, and verified thereafter by fiberoptic endoscopy. We found the clinical judgment to be correct in only 70% (for aspiration of saliva), 55% (of puree), and 67% (of thin liquids). We conclude that, because of this unacceptably high error rate of clinical assessment, a fiberoptic evaluation of swallowing is a necessary diagnostic step both for the planning of therapy and for the development of feeding strategies in children and adolescents with neurogenic dysphagia. Georg Thieme Verlag KG Stuttgart · New York.

  11. Particle control in high power, high density long pulses on Tore Supra

    Energy Technology Data Exchange (ETDEWEB)

    Bucalossi, J.; Brosset, C.; Dufour, E.; Loarer, T.; Pegourie, B.; Tsitrone, E.; Basiuk, V.; Bremond, S.; Chantant, M.; Colas, L.; Commaux, N.; Geraud, A.; Grosman, A.; Guirlet, R.; Gunn, J.; Hertout, P.; Hoang, G.T.; Kazarian, F.; Mazon, D.; Maget, P.; Mitteau, R.; Monier-Garbet, P.; Moreau, P.; Saint-Laurent, F.; Schunke, B.; Vallet, J.C

    2005-07-01

    The plasma density and impurity level (Z(eff) {approx} 2) are perfectly controlled all along the 6 minute long discharges, the main limitation coming from the LH (lower hybrid) power source. After 60 s, the particle injection rate and the particle exhaust rate are constant. Therefore the retention rate, defined as the difference between these 2 quantities, is also constant at about 3.10{sup 20} D/s. These discharges were performed at low density and with LHCD (lower hybrid current drive). A new scenario has been recently developed combining ICRH (ion cyclotron resonance heating) and LHCD up to a total power of 10 MW at higher density and limited in time to 60 s by the capability of the ICRH heating systems. The infrared imaging protection system reveals lots of hot spots on the plasma facing components. These localized heat loads are attributed mainly to the fast particles which are accelerated in the near field generated by the IC and LH launchers. The gas injection rate necessary to maintain the plasma density in the high power high density scenarios (LHCD + ICRH) is substantially increased (up to a factor 3). Particle balance analysis based on pressure measurements shows that the absolute in-vessel retention rate, computed after 30 s of plasma is roughly equivalent in both scenarios (3.10{sup 20} D/s), whatever the ICRH power (from 0 to 4 MW) and the line integrated plasma density (from 2.5 to 4.10{sup 19} m{sup -2}) are. This result could indicate that the retention mechanisms could be dominated by wall processes such as diffusion in carbon porosities rather than plasma processes such as co-deposition, dependent on edge conditions. (A.C.)

  12. Ultra-high cell-density silicon photomultipliers with high detection efficiency

    Science.gov (United States)

    Acerbi, Fabio; Gola, Alberto; Regazzoni, Veronica; Paternoster, Giovanni; Borghi, Giacomo; Piemonte, Claudio; Zorzi, Nicola

    2017-05-01

    Silicon photomultipliers (SiPMs) are arrays of many single-photon avalanche diodes (SPADs), all connected in parallel. Each SPAD is sensitive to single photons and the SiPM gives an output proportional to the number of detected photons. These sensors are becoming more and more popular in different applications, from high-energy physics to spectroscopy, and they have been significantly improved over last years, decreasing the noise, increasing the cell fill-factor (FF) and thus achieving very high photon-detection efficiency (PDE). In FBK (Trento, Italy), we developed new SiPM technologies with high-density (HD) and, more recently, ultra-high-density (UHD) of cells (i.e. density of SPADs). These technologies employ deep-trenches between cells, for electrical and optical isolation. As an extreme case the smallest-cell, SiPM, i.e. with 5μm cell pitch, has about 40000 SPADs per squared millimeter. Such small SPAD dimensions gives a significantly high dynamic range to the SiPM. These small-cells SiPM have a lower correlated noise (including lower afterpulsing probability) and a faster recharge time (in the order of few nanoseconds), and they also preserve a very good detection efficiency (despite the small SPAD dimension).

  13. High energy-density liquid rocket fuel performance

    Science.gov (United States)

    Rapp, Douglas C.

    1990-01-01

    A fuel performance database of liquid hydrocarbons and aluminum-hydrocarbon fuels was compiled using engine parametrics from the Space Transportation Engine Program as a baseline. Propellant performance parameters are introduced. General hydrocarbon fuel performance trends are discussed with respect to hydrogen-to-carbon ratio and heat of formation. Aluminum-hydrocarbon fuel performance is discussed with respect to aluminum metal loading. Hydrocarbon and aluminum-hydrocarbon fuel performance is presented with respect to fuel density, specific impulse and propellant density specific impulse.

  14. Current-voltage curve of a bipolar membrane at high current density

    NARCIS (Netherlands)

    Aritomi, T.; Boomgaard, van den Th.; Strathmann, H.

    1996-01-01

    The potential drop across a bipolar membrane was measured as a function of the applied current density. As a result, an inflection point was observed in the obtained current-voltage curve at high current density. This inflection point indicates that at high current densities water supply from outsid

  15. Current-voltage curve of a bipolar membrane at high current density

    NARCIS (Netherlands)

    Aritomi, T.; van den Boomgaard, Anthonie; Strathmann, H.

    1996-01-01

    The potential drop across a bipolar membrane was measured as a function of the applied current density. As a result, an inflection point was observed in the obtained current-voltage curve at high current density. This inflection point indicates that at high current densities water supply from

  16. OXIDATION OF DRY HYDROCARBONS AT HIGH-POWER DENSITY ANODES

    Energy Technology Data Exchange (ETDEWEB)

    K.Krist; O. Spaldon-Stewart; R. Remick

    2004-03-01

    This work builds upon discoveries by the University of Pennsylvania and others pertaining to the oxidation of dry hydrocarbon fuels in high temperature solid oxide fuel cells. The work reported here was restricted primarily to dry methane and confirms that YSZ-based cells, having ceria in the anode as a catalyst and copper in the anode as a current collector, can operate on dry methane for extended periods. Thirty-three lab-scale cells of various designs were fabricated and operated under a variety of conditions. The longest-lived cell gave stable performance on dry methane at 800 C for over 305 hours. Only slight carbon deposition was noted at the completion of the test. A corresponding nickel/YSZ-based anode would have lasted for less than an hour under these test conditions (which included open circuit potential measurements) before carbon fouling essentially destroyed the cell. The best performing cell achieved 112 mW/cm{sub 2} on dry methane at 800 C. Several problems were encountered with carbon fouling and declining open circuit voltages in many of the test cells after switching from operation on hydrogen to dry methane. Although not rigorously confirmed by experimentation, the results suggested that air infiltration through less than perfect perimeter seals or pinholes in the electrolytes, or both gave rise to conditions that caused the carbon fouling and OCV decline. Small amounts of air reacting with methane in a partial oxidation reaction could produce carbon monoxide that, in turn, would deposit the carbon. If this mechanism is confirmed, it implies that near perfect hardware is required for extended operation. Some evidence was also found for the formation of electrical shorts, probably from carbon deposits bridging the electrolyte. Work with odorized methane and with methane containing 100-ppm hydrogen sulfide confirmed that copper is stable at 800 C in dry hydrocarbon fuels in the presence of sulfur. In a number of cases, but not exclusively, the

  17. Biofuels Barrier Properties of Polyamide 6 and High Density Polyethylene

    Directory of Open Access Journals (Sweden)

    Fillot L.-A.

    2015-02-01

    Full Text Available In this paper, a comparison of the biofuels barrier properties of PolyAmide 6 (PA6 and High Density PolyEthylene (HDPE is presented. Model fuels were prepared as mixtures of toluene, isooctane and ethanol, the ethanol volume fraction varying between 0% and 100%. Barrier properties were determined at 40°C by gravimetric techniques or gas chromatography measurements, and it was shown that polyamide 6 permeability is lower than that of polyethylene on a wide range of ethanol contents up to 85% of ethanol (E85 in the biofuel, permeability of PA6 being 100 times lower than that of HDPE for low ethanol content fuels (E5, E0. The time-lags were also compared, and on the whole range of ethanol contents, HDPE permeation kinetics appears to be much faster than that of PA6, the time lag for a 1 mm thick specimens in presence of E10 being 50 days for PA6 and 0.5 days for HDPE. The compositions of the solvent fluxes were analyzed by FID gas chromatography, and it turned out that the solvent flux was mainly made up of ethanol (minimum 95% in the case of PA6, whereas in the case of HDPE, solvent flux was mainly made up of hydrocarbons. The implication of this difference in the solvent flux composition is discussed in the present article, and a side effect called the “fuel exhaustion process” is presented. The influence of the sample thickness was then studied, and for the different biofuels compositions, the pervaporation kinetics of polyamide 6 appeared to evolve with the square of the thickness, a long transitory regime being highlighted in the case of PA6. This result implies that the time needed to characterize the steady state permeability of thick PA6 parts such as fuel tanks can be very long (one year or more, this duration being far superior to the Euros 5 or Euro 6 standard emission measurements time scale. The influence of temperature on the permeability was finally assessed, and the activation energy that is the signature of the temperature

  18. Human endothelial progenitor cells internalize high-density lipoprotein.

    Science.gov (United States)

    Srisen, Kaemisa; Röhrl, Clemens; Meisslitzer-Ruppitsch, Claudia; Ranftler, Carmen; Ellinger, Adolf; Pavelka, Margit; Neumüller, Josef

    2013-01-01

    Endothelial progenitor cells (EPCs) originate either directly from hematopoietic stem cells or from a subpopulation of monocytes. Controversial views about intracellular lipid traffic prompted us to analyze the uptake of human high density lipoprotein (HDL), and HDL-cholesterol in human monocytic EPCs. Fluorescence and electron microscopy were used to investigate distribution and intracellular trafficking of HDL and its associated cholesterol using fluorescent surrogates (bodipy-cholesterol and bodipy-cholesteryl oleate), cytochemical labels and fluorochromes including horseradish peroxidase and Alexa Fluor® 568. Uptake and intracellular transport of HDL were demonstrated after internalization periods from 0.5 to 4 hours. In case of HDL-Alexa Fluor® 568, bodipy-cholesterol and bodipy-cholesteryl oleate, a photooxidation method was carried out. HDL-specific reaction products were present in invaginations of the plasma membrane at each time of treatment within endocytic vesicles, in multivesicular bodies and at longer periods of uptake, also in lysosomes. Some HDL-positive endosomes were arranged in form of "strings of pearl"- like structures. HDL-positive multivesicular bodies exhibited intensive staining of limiting and vesicular membranes. Multivesicular bodies of HDL-Alexa Fluor® 568-treated EPCs showed multilamellar intra-vacuolar membranes. At all periods of treatment, labeled endocytic vesicles and organelles were apparent close to the cell surface and in perinuclear areas around the Golgi apparatus. No HDL-related particles could be demonstrated close to its cisterns. Electron tomographic reconstructions showed an accumulation of HDL-containing endosomes close to the trans-Golgi-network. HDL-derived bodipy-cholesterol was localized in endosomal vesicles, multivesicular bodies, lysosomes and in many of the stacked Golgi cisternae and the trans-Golgi-network Internalized HDL-derived bodipy-cholesteryl oleate was channeled into the lysosomal intraellular

  19. Human endothelial progenitor cells internalize high-density lipoprotein.

    Directory of Open Access Journals (Sweden)

    Kaemisa Srisen

    Full Text Available Endothelial progenitor cells (EPCs originate either directly from hematopoietic stem cells or from a subpopulation of monocytes. Controversial views about intracellular lipid traffic prompted us to analyze the uptake of human high density lipoprotein (HDL, and HDL-cholesterol in human monocytic EPCs. Fluorescence and electron microscopy were used to investigate distribution and intracellular trafficking of HDL and its associated cholesterol using fluorescent surrogates (bodipy-cholesterol and bodipy-cholesteryl oleate, cytochemical labels and fluorochromes including horseradish peroxidase and Alexa Fluor® 568. Uptake and intracellular transport of HDL were demonstrated after internalization periods from 0.5 to 4 hours. In case of HDL-Alexa Fluor® 568, bodipy-cholesterol and bodipy-cholesteryl oleate, a photooxidation method was carried out. HDL-specific reaction products were present in invaginations of the plasma membrane at each time of treatment within endocytic vesicles, in multivesicular bodies and at longer periods of uptake, also in lysosomes. Some HDL-positive endosomes were arranged in form of "strings of pearl"- like structures. HDL-positive multivesicular bodies exhibited intensive staining of limiting and vesicular membranes. Multivesicular bodies of HDL-Alexa Fluor® 568-treated EPCs showed multilamellar intra-vacuolar membranes. At all periods of treatment, labeled endocytic vesicles and organelles were apparent close to the cell surface and in perinuclear areas around the Golgi apparatus. No HDL-related particles could be demonstrated close to its cisterns. Electron tomographic reconstructions showed an accumulation of HDL-containing endosomes close to the trans-Golgi-network. HDL-derived bodipy-cholesterol was localized in endosomal vesicles, multivesicular bodies, lysosomes and in many of the stacked Golgi cisternae and the trans-Golgi-network Internalized HDL-derived bodipy-cholesteryl oleate was channeled into the lysosomal

  20. Test of high density UC targets development at Gatchina for neutron rich radioactive beam facilities

    CERN Document Server

    Lhersonneau, G; Lanchais, A; Rizzi, V; Tecchio, L.B; Bajeat, O; Essabaa, S; Lau, C; Cheikh Mhamed, M; Roussière, B; Barzakh, A.E; Fedorov, D.V; lonan, A.M; lvanov, V.S; Mezilev, K.A; Moroz, F.V; Orlov, S.YU; Panteleevc, V.N; Volkovc, YU.M; Dubois, M; Eléon, C; Gaubert, G; Jardin, P; Leroy, R; Saint Laurent, M.G; Villari, A.C.C; Stroe, L; 10.1016/j.nimb.2008.05.033

    2008-01-01

    Production of on-line mass separator neutron rich isotopes using fission induced by 1 GeV protons on high density uranium carbide has been investigate and results compared with the low density targets yields.

  1. Stability Of Rubble Mound Breakwaters Using High Density Rock

    DEFF Research Database (Denmark)

    Burcharth, H. F.; Beck, J. B.

    2000-01-01

    The present paper discusses the effect of mass density on stability of rubble mound breakwaters. A short literature review of existing knowledge is give to establish a background for the ongoing research. Furthermore, several model tests are described in which the stability of rubble mound breakw...

  2. Formation of Los Angeles's low density and high car dependence

    Institute of Scientific and Technical Information of China (English)

    DAI Te-qi; JIN Feng-jun

    2009-01-01

    As a typical car-dependent city, Los Angeles (LA) is extensively used as an example in research to illustrate car influences on city form. Focusing on the features of LA's geologic conditions and civil circumstances, we argued that the relationship between LA's low-density pattern and car dependence is more involved than previously deemed simple causality. The low density should be primarily credited to the spacious requirement of the mining industry, frequent earthquakes and multiethnic population of the city. Oil reserves in LA fueled its economic boom and fast urbanization that coincided with the start of mass production of cheap cars, and cars became medium-priced consumables for average families. Politicians preference for short construction-peried projects enabled fast establishment of LA's highway infrastructure. The popularity of car use in return faciliatated further development of the low-density pattern of the city. The low-density urban form and car dependence created environmental and social problems for LA. Looking at P. R. China's motorization and urban development, we found that the trajectory of Beijing's motorization between 1978 and 2003 coincides with that of the U.S. in the 1910s and 1920s. Lessons from LA's urban and transportation development should be suggestive to China's urban and transportation planning.

  3. Patterned magnetic thin films for ultra high density recording

    NARCIS (Netherlands)

    Lodder, J.C.; Haast, M.A.M.; Abelmann, L.; Hadjipanayis, G.C.

    2001-01-01

    The areal bit density of magnetic disk recording has increased since 1990 60% per year and even in the last years 100%. Extrapolation of these rates leads to recording parameters not likely to be achieved without changes in the present way of storing hard disk data. One of the possible solutions is

  4. Fiber-Optic Chemical Sensors and Fiber-Optic Bio-Sensors

    Directory of Open Access Journals (Sweden)

    Marie Pospíšilová

    2015-09-01

    Full Text Available This review summarizes principles and current stage of development of fiber-optic chemical sensors (FOCS and biosensors (FOBS. Fiber optic sensor (FOS systems use the ability of optical fibers (OF to guide the light in the spectral range from ultraviolet (UV (180 nm up to middle infrared (IR (10 μm and modulation of guided light by the parameters of the surrounding environment of the OF core. The introduction of OF in the sensor systems has brought advantages such as measurement in flammable and explosive environments, immunity to electrical noises, miniaturization, geometrical flexibility, measurement of small sample volumes, remote sensing in inaccessible sites or harsh environments and multi-sensing. The review comprises briefly the theory of OF elaborated for sensors, techniques of fabrications and analytical results reached with fiber-optic chemical and biological sensors.

  5. ADX: a high field, high power density, Advanced Divertor test eXperiment

    Science.gov (United States)

    Vieira, R.; Labombard, B.; Marmar, E.; Irby, J.; Shiraiwa, S.; Terry, J.; Wallace, G.; Whyte, D. G.; Wolfe, S.; Wukitch, S.; ADX Team

    2014-10-01

    The MIT PSFC and collaborators are proposing an advanced divertor experiment (ADX) - a tokamak specifically designed to address critical gaps in the world fusion research program on the pathway to FNSF/DEMO. This high field (6.5 tesla, 1.5 MA), high power density (P/S ~ 1.5 MW/m2) facility would utilize Alcator magnet technology to test innovative divertor concepts for next-step DT fusion devices (FNSF, DEMO) at reactor-level boundary plasma pressures and parallel heat flux densities while producing high performance core plasma conditions. The experimental platform would also test advanced lower hybrid current drive (LHCD) and ion-cyclotron range of frequency (ICRF) actuators and wave physics at the plasma densities and magnetic field strengths of a DEMO, with the unique ability to deploy launcher structures both on the low-magnetic-field side and the high-field side - a location where energetic plasma-material interactions can be controlled and wave physics is most favorable for efficient current drive, heating and flow drive. This innovative experiment would perform plasma science and technology R&D necessary to inform the conceptual development and accelerate the readiness-for-deployment of FNSF/DEMO - in a timely manner, on a cost-effective research platform. Supported by DE-FC02-99ER54512.

  6. Partially reduced graphene oxide based FRET on fiber-optic interferometer for biochemical detection

    Science.gov (United States)

    Yao, B. C.; Wu, Y.; Yu, C. B.; He, J. R.; Rao, Y. J.; Gong, Y.; Fu, F.; Chen, Y. F.; Li, Y. R.

    2016-03-01

    Fluorescent resonance energy transfer (FRET) with naturally exceptional selectivity is a powerful technique and widely used in chemical and biomedical analysis. However, it is still challenging for conventional FRET to perform as a high sensitivity compact sensor. Here we propose a novel ‘FRET on Fiber’ concept, in which a partially reduced graphene oxide (prGO) film is deposited on a fiber-optic modal interferometer, acting as both the fluorescent quencher for the FRET and the sensitive cladding for optical phase measurement due to refractive index changes in biochemical detection. The target analytes induced fluorescence recovery with good selectivity and optical phase shift with high sensitivity are measured simultaneously. The functionalized prGO film coated on the fiber-optic interferometer shows high sensitivities for the detections of metal ion, dopamine and single-stranded DNA (ssDNA), with detection limits of 1.2 nM, 1.3 μM and 1 pM, respectively. Such a prGO based ‘FRET on fiber’ configuration, bridging the FRET and the fiber-optic sensing technology, may serve as a platform for the realization of series of integrated ‘FRET on Fiber’ sensors for on-line environmental, chemical, and biomedical detection, with excellent compactness, high sensitivity, good selectivity and fast response

  7. Guiding and collimating the fast electrons by using a low-density-core target with buried high density layers

    Science.gov (United States)

    Lv, Chong; Wan, Feng; Hou, Ya-Juan; Jia, Mo-Ran; Sang, Hai-Bo; Xie, Bai-Song; Liu, Shi-Bing

    2017-02-01

    A low-density-core target with buried high density layers is proposed to improve the transport of fast electrons and involved problems are investigated by using two-dimensional particle-in-cell simulations. It is demonstrated that this target can collimate the fast electrons efficiently and lead to a better beam quality. The enhancement is attributed to the weakening of the two stream instability and the better collimation by the self-generated multilayer megagauss magnetic field as well as the baroclinic magnetic field. Comparing this to that without buried high density layers, the energy flux of fast electrons is increased by a factor of about 1.8 and has a narrower transverse distribution in space. Besides, the dependence of the efficiency on the target parameters is examined, and the optimal target parameters are also obtained. Such a target can be useful to many applications, such as fast ignition in inertial fusion.

  8. Cooling Concepts for High Power Density Magnetic Devices

    Science.gov (United States)

    Biela, Juergen; Kolar, Johann W.

    In the area or power electronics there is a general trend to higher power densities. In order to increase the power density the systems must be designed optimally concerning topology, semiconductor selection, etc. and the volume of the components must be decreased. The decreasing volume comes along with a reduced surface for cooling. Consequently, new cooling methods are required. In the paper an indirect air cooling system for magnetic devices which combines the transformer with a heat sink and a heat transfer component is presented. Moreover, an analytic approach for calculating the temperature distribution is derived and validated by measurements. Based on these equations a transformer with an indirect air cooling system is designed for a 10kW telecom power supply.

  9. High Volumetric Energy Density Hybrid Supercapacitors Based on Reduced Graphene Oxide Scrolls.

    Science.gov (United States)

    Rani, Janardhanan R; Thangavel, Ranjith; Oh, Se-I; Woo, Jeong Min; Chandra Das, Nayan; Kim, So-Yeon; Lee, Yun-Sung; Jang, Jae-Hyung

    2017-07-12

    The low volumetric energy density of reduced graphene oxide (rGO)-based electrodes limits its application in commercial electrochemical energy storage devices that require high-performance energy storage capacities in small volumes. The volumetric energy density of rGO-based electrode materials is very low due to their low packing density. A supercapacitor with enhanced packing density and high volumetric energy density is fabricated using doped rGO scrolls (GFNSs) as the electrode material. The restacking of rGO sheets is successfully controlled through synthesizing the doped scroll structures while increasing the packing density. The fabricated cell exhibits an ultrahigh volumetric energy density of 49.66 Wh/L with excellent cycling stability (>10 000 cycles). This unique design strategy for the electrode material has significant potential for the future supercapacitors with high volumetric energy densities.

  10. Fiberoptic bronchoscopy-assisted endotracheal intubation in a patient with a large tracheal tumor.

    Science.gov (United States)

    Pang, Lei; Feng, Yan-Hua; Ma, Hai-Chun; Dong, Su

    2015-04-01

    In the event of a high degree of airway obstruction, endotracheal intubation can be impossible and even dangerous, because it can cause complete airway obstruction, especially in patients with high tracheal lesions. However, a smaller endotracheal tube under the guidance of a bronchoscope can be insinuated past obstructive tumor in most noncircumferential cases. Here we report a case of successful fiberoptic bronchoscopy-assisted endotracheal intubation in a patient undergoing surgical resection of a large, high tracheal tumor causing severe tracheal stenosis. A 42-year-old Chinese man presented with dyspnea, intermittent irritable cough, and sleep deprivation for one and a half years. X-rays and computed tomography scan of the chest revealed an irregular pedunculated soft tissue mass within the tracheal lumen. The mass occupied over 90% of the lumen and caused severe tracheal stenosis. Endotracheal intubation was done to perform tracheal tumor resection under general anesthesia. After several failed conventional endotracheal intubation attempts, fiberoptic bronchoscopy-assisted intubation was successful. The patient received mechanical ventilation and then underwent tumor resection and a permanent tracheostomy. This case provides evidence of the usefulness of the fiberoptic bronchoscopy-assisted intubation technique in management of an anticipated difficult airway and suggests that tracheal intubation can be performed directly in patients with a tracheal tumor who can sleep in the supine position, even if they have occasional sleep deprivation and severe tracheal obstruction as revealed by imaging techniques.

  11. Publications of Proceedings for the RF 2005 7th Workshop on High Energy Density and High Power RF

    Energy Technology Data Exchange (ETDEWEB)

    Luhmann, Jr, N C

    2006-01-01

    The University of California, Davis hosted the High Energy Density and High Power RF 7th Workshop on High Energy Density and High Power RF in Kalamata, Greece, 13-17 June, 2005. The Proceedings cost was supported by these funds from the U.S. Department of Energy. The Proceedings was published through the American Institute of Physics.

  12. Fiber-optic Doppler velocimeter based on a dual-polarization fiber grating laser

    Science.gov (United States)

    Kuang, Zeyuang; Cheng, Linghao; Liang, Yizhi; Liang, Hao; Guan, Bai-Ou

    2015-07-01

    A fiber-optic Doppler velocimeter based on a dual-polarization fiber grating laser is demonstrated. The fiber grating laser produces two orthogonally polarized laser outputs with their frequency difference proportional to the intra-cavity birefringence. When the laser outputs are reflected from a moving targets, the laser frequencies will be shifted due to the Doppler effect. It shows that the frequency difference between the beat note of the laser outputs and the beat note of the reflected lasers is proportional to the velocity. The proposed fiber-optic Doppler velocimeter shows a high sensitivity of 0.64 MHz/m/s and is capable of measurement of wide range of velocity.

  13. Extract of mangosteen increases high density lipoprotein levels in rats fed high lipid

    Directory of Open Access Journals (Sweden)

    Dwi Laksono Adiputro

    2015-12-01

    Full Text Available BACKGROUND In cardiovascular medicine, Garcinia mangostana has been used as an antioxidant to inhibit oxidation of low density lipoproteins and as an antiobesity agent. The effect of Garcinia mangostana on hyperlipidemia is unknown. The aim of this study was to evaluate the effect of an ethanolic extract of Garcinia mangostana pericarp on lipid profile in rats fed a high lipid diet. METHODS A total of 40 rats were divided into five groups control, high lipid diet, and high lipid diet + ethanolic extract of Garcinia mangostana pericarp at dosages of 200, 400, and 800 mg/kg body weight. The control group received a standard diet for 60 days. The high lipid diet group received standard diet plus egg yolk, goat fat, cholic acid, and pig fat for 60 days with or without ethanolic extract of Garcinia mangostana pericarp by the oral route. After 60 days, rats were anesthesized with ether for collection of blood by cardiac puncture. Analysis of blood lipid profile comprised colorimetric determination of cholesterol, triglyceride, low density lipoprotein (LDL, and high density lipoprotein (HDL. RESULTS From the results of one-way ANOVA it was concluded that there were significant between-group differences in cholesterol, trygliceride, LDL, and HDL levels (p=0.000. Ethanolic extract of Garcinia mangostana pericarp significantly decreased cholesterol, trygliceride, and LDL levels, starting at 400 mg/kg body weight (p=0.000. Ethanolic extract of Garcinia mangostana pericarp significantly increased HDL level starting at 200 mg/kg body weight (p=0.000. CONCLUSION Ethanolic extract of Garcinia mangostana pericarp has a beneficial effect on lipid profile in rats on a high lipid diet.

  14. Reliability of High I/O High Density CCGA Interconnect Electronic Packages under Extreme Thermal Environment

    Science.gov (United States)

    Ramesham, Rajeshuni

    2012-01-01

    This paper provides the experimental test results of advanced CCGA packages tested in extreme temperature thermal environments. Standard optical inspection and x-ray non-destructive inspection tools were used to assess the reliability of high density CCGA packages for deep space extreme temperature missions. Ceramic column grid array (CCGA) packages have been increasing in use based on their advantages such as high interconnect density, very good thermal and electrical performances, compatibility with standard surface-mount packaging assembly processes, and so on. CCGA packages are used in space applications such as in logic and microprocessor functions, telecommunications, payload electronics, and flight avionics. As these packages tend to have less solder joint strain relief than leaded packages or more strain relief over lead-less chip carrier packages, the reliability of CCGA packages is very important for short-term and long-term deep space missions. We have employed high density CCGA 1152 and 1272 daisy chained electronic packages in this preliminary reliability study. Each package is divided into several daisy-chained sections. The physical dimensions of CCGA1152 package is 35 mm x 35 mm with a 34 x 34 array of columns with a 1 mm pitch. The dimension of the CCGA1272 package is 37.5 mm x 37.5 mm with a 36 x 36 array with a 1 mm pitch. The columns are made up of 80% Pb/20%Sn material. CCGA interconnect electronic package printed wiring polyimide boards have been assembled and inspected using non-destructive x-ray imaging techniques. The assembled CCGA boards were subjected to extreme temperature thermal atmospheric cycling to assess their reliability for future deep space missions. The resistance of daisy-chained interconnect sections were monitored continuously during thermal cycling. This paper provides the experimental test results of advanced CCGA packages tested in extreme temperature thermal environments. Standard optical inspection and x-ray non

  15. Reliability of High I/O High Density CCGA Interconnect Electronic Packages under Extreme Thermal Environment

    Science.gov (United States)

    Ramesham, Rajeshuni

    2012-01-01

    This paper provides the experimental test results of advanced CCGA packages tested in extreme temperature thermal environments. Standard optical inspection and x-ray non-destructive inspection tools were used to assess the reliability of high density CCGA packages for deep space extreme temperature missions. Ceramic column grid array (CCGA) packages have been increasing in use based on their advantages such as high interconnect density, very good thermal and electrical performances, compatibility with standard surface-mount packaging assembly processes, and so on. CCGA packages are used in space applications such as in logic and microprocessor functions, telecommunications, payload electronics, and flight avionics. As these packages tend to have less solder joint strain relief than leaded packages or more strain relief over lead-less chip carrier packages, the reliability of CCGA packages is very important for short-term and long-term deep space missions. We have employed high density CCGA 1152 and 1272 daisy chained electronic packages in this preliminary reliability study. Each package is divided into several daisy-chained sections. The physical dimensions of CCGA1152 package is 35 mm x 35 mm with a 34 x 34 array of columns with a 1 mm pitch. The dimension of the CCGA1272 package is 37.5 mm x 37.5 mm with a 36 x 36 array with a 1 mm pitch. The columns are made up of 80% Pb/20%Sn material. CCGA interconnect electronic package printed wiring polyimide boards have been assembled and inspected using non-destructive x-ray imaging techniques. The assembled CCGA boards were subjected to extreme temperature thermal atmospheric cycling to assess their reliability for future deep space missions. The resistance of daisy-chained interconnect sections were monitored continuously during thermal cycling. This paper provides the experimental test results of advanced CCGA packages tested in extreme temperature thermal environments. Standard optical inspection and x-ray non

  16. Fabrication of fiber-optic localized surface plasmon resonance sensor and its application to detect antibody-antigen reaction of interferon-gamma

    Science.gov (United States)

    Jeong, Hyeon-Ho; Erdene, Norov; Lee, Seung-Ki; Jeong, Dae-Hong; Park, Jae-Hyoung

    2011-12-01

    A fiber-optic localized surface plasmon (FO LSPR) sensor was fabricated by gold nanoparticles (Au NPs) immobilized on the end-face of an optical fiber. When Au NPs were formed on the end-face of an optical fiber by chemical reaction, Au NPs aggregation occurred and the Au NPs were immobilized in various forms such as monomers, dimers, trimers, etc. The component ratio of the Au NPs on the end-face of the fabricated FO LSPR sensor was slightly changed whenever the sensors were fabricated in the same condition. Including this phenomenon, the FO LSPR sensor was fabricated with high sensitivity by controlling the density of Au NPs. Also, the fabricated sensors were measured for the resonance intensity for the different optical systems and analyzed for the effect on sensitivity. Finally, for application as a biosensor, the sensor was used for detecting the antibody-antigen reaction of interferon-gamma.

  17. Effects of high density on spacing behaviour and reproduction in Akodon azarae: A fencing experiment

    Science.gov (United States)

    Ávila, Belén; Bonatto, Florencia; Priotto, José; Steinmann, Andrea R.

    2016-01-01

    We studied the short term spacing behavioural responses of Pampean grassland mouse (Akodon azarae) with regard to population density in four 0.25 ha enclosures (two control and two experimental) in the 2011 breeding season. Based on the hypothesis that A. azarae breeding females exhibit spacing behaviour, and breeding males show a fusion spatial response, we tested the following predictions: (1) home range size and intrasexual overlap degree of females are independent of population density values; (2) at high population density, home range size of males decreases and the intrasexual home range overlap degree increases. To determine if female reproductive success decreases at high population density, we analyzed pregnancy rate, size and weight of litters, and period until fecundation in both low and high enclosure population density. We found that both males and females varied their home range size in relation to population density. Although male home ranges were always bigger than those of females in populations with high density, home range sizes of both sexes decreased. Females kept exclusive home ranges independent of density values meanwhile males decreased home range overlap in high breeding density populations. Although females produced litters of similar size in both treatments, weight of litter, pregnant rate and period until fecundation varied in relation to population density. Our results did not support the hypothesis that at high density females of A. azarae exhibit spacing behaviour neither that males exhibit a fusion spatial response.

  18. Effect of discrete track medium at high areal density

    Science.gov (United States)

    Kaizu, Akimasa; Soeno, Yoshikazu; Tagami, Katsumichi

    The degradation of SNR caused by the higher uniaxial crystalline anisotropy field (Hk) of medium and small write fields of narrower write width is one of the problems for achieving higher areal density. The SNR dependence on Hk of a medium with different write fields of head using the discrete track medium (DTM) is investigated by using micromagnetics simulation. As a result, the curves of SNR as a function of Hk have peak values. In DTM, the peak values of SNR are almost constant at any Hk of the medium and different write fields. Higher SNR is realized even at low Hk and small write field in DTM.

  19. Implementing an Inexpensive and Accurate Introductory Gas Density Activity with High School Students

    Science.gov (United States)

    Cunningham, W. Patrick; Joseph, Christopher; Morey, Samantha; Santos Romo, Ana; Shope, Cullen; Strang, Jonathan; Yang, Kevin

    2015-01-01

    A simplified activity examined gas density while employing cost-efficient syringes in place of traditional glass bulbs. The exercise measured the density of methane, with very good accuracy and precision, in both first-year high school and AP chemistry settings. The participating students were tasked with finding the density of a gas. The…

  20. Cultivar and Tree Density As Key Factors in the Long-Term Performance of Super High-Density Olive Orchards.

    Science.gov (United States)

    Díez, Concepción M; Moral, Juan; Cabello, Diego; Morello, Pablo; Rallo, Luis; Barranco, Diego

    2016-01-01

    Super high-density (SHD) olive orchards are rapidly expanding since the first plantation was set up in Spain in the 1990s. Because there are no long-term studies characterizing these systems, it is unknown if densities above a certain threshold could trigger competition among fully-grown trees, compromising their development. Over 14 years we have evaluated the performance of the major olive cultivars currently planted in SHD systems ("Arbequina," Arbequina IRTA-i·18, "Arbosana," "Fs-17," and "Koroneiki") and nine SHD designs ranging from 780 to 2254 trees ha(-1) for the cultivar "Arbequina." Remarkably, the accumulated fruit and oil production of the five cultivars increased linearly over time. Our data indicated the favorable long-term performance of the evaluated cultivars with an average annual oil production of 2.3 t ha(-1). Only "Fs-17" did not perform well to the SHD system in our conditions and it yielded about half (1.2 t ha(-1)) of the other cultivars. In the density trial for "Arbequina," both fruit and oil accumulated production increased over time as a function of tree density. Thus, the accumulated oil yield ranged from 16.1 t ha(-1) for the lowest density (780 trees ha(-1)) to 29.9 t ha(-1) for the highest (2254 trees ha(-1)). In addition, we note that the accumulated production per surface unit showed a better correlation with the hedgerow length than the tree density. Thus, the current planting designs of SHD olive orchards can be further improved taking this parameter into account. Despite observations that some irregular patterns of crop distribution have arisen, our olive hedgerows are still fully productive after 14 years of planting. This result contradicts previous experiences that showed declines in production 7 or 8 years after planting due to high vigor, shading, and limited ventilation.

  1. Towards High Density 3-D Memory in Diamond

    Science.gov (United States)

    Henshaw, Jacob; Dhomkar, Siddharth; Meriles, Carlos; Jayakumar, Harishankar

    The nitrogen-vacancy (NV) center in diamond is presently the focus of widespread attention for applications ranging from quantum information processing to nanoscale metrology. Of great utility is the ability to optically initialize the NV charge state, which has an immediate impact on the center's light emission properties. Here, we use two-color microscopy in NV-rich, type-1b diamond to demonstrate fluorescence-encoded long-term storage of classical information. As a proof of principle, we write, reset, and rewrite various patterns with 2-D binary bit density comparable to present DVD-ROM technology. The strong fluorescence signal originating from the diffraction-limited bit volume allows us to transition from binary to multi-valued encoding, which translates into a significant storage capacity boost. Finally, we show that our technique preserves information written on different planes of the diamond crystal and thus serves as a platform for three-dimensional storage. Substantial enhancement in the bit density could be achieved with the aid of super resolution microscopy techniques already employed to discriminate between NVs with sub-diffraction, nanometer accuracy, a regime where the storage capacity could exceed 1017 bytes/cm3 We acknowledge support from the National Science Foundation through Grant NSF-1314205.

  2. High energy density supercapacitors using macroporous kitchen sponges

    KAUST Repository

    Chen, Wei

    2012-01-01

    Macroporous, low-cost and recyclable kitchen sponges are explored as effective electrode platforms for supercapacitor devices. A simple and scalable process has been developed to fabricate MnO 2-carbon nanotube (CNT)-sponge supercapacitor electrodes using ordinary kitchen sponges. Two organic electrolytes (1 M of tetraethylammonium tetrafluoroborate (Et 4NBF 4) in propylene carbonate (PC), 1 M of LiClO 4 in PC) are utilized with the sponge-based electrodes to improve the energy density of the symmetrical supercapacitors. Compared to aqueous electrolyte (1 M of Na 2SO 4 in H 2O), the energy density of supercapacitors tripled in Et 4NBF 4 electrolyte, and further increased by six times in LiClO 4 electrolyte. The long-term cycling performance in different electrolytes was examined and the morphology changes of the electrode materials were also studied. The good electrochemical performance in both aqueous and organic electrolytes indicates that the MnO 2-CNT-sponge is a promising low-cost electrode for energy storage systems. © 2012 The Royal Society of Chemistry.

  3. Multimode fiber for high-density optical interconnects

    Science.gov (United States)

    Bickham, Scott R.; Ripumaree, Radawan; Chalk, Julie A.; Paap, Mark T.; Hurley, William C.; McClure, Randy L.

    2017-02-01

    Data centers (DCs) are facing the challenge of delivering more capacity over longer distances. As line rates increase to 25 Gb/s and higher, DCs are being challenged with signal integrity issues due to the long electrical traces that require retiming. In addition, the density of interconnects on the front panel is limited by the size and power dissipation requirements of the pluggable modules. One proposal to overcome these issues is to use embedded optical transceivers in which optical fibers are used to transport data to and from the front panel. These embedded modules will utilize arrays of VCSEL or silicon-photonic transceivers, and in both cases, the capacity may be limited by the density of the optical connections on the chip. To address this constraint, we have prototyped optical fibers in which the glass and coating diameters are reduced to 80 and 125 microns, respectively. These smaller diameters enable twice as many optical interconnects in the same footprint, and this in turn will allow the transceiver arrays to be collinearly located on small chips with dimensions on the order of (5x5mm2)1,2. We have also incorporated these reduced diameter fibers into small, flexible 8-fiber ribbon cables which can simplify routing constraints inside modules and optical backplanes.

  4. Advanced Cathode Material For High Energy Density Lithium-Batteries Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Advanced cathode materials having high red-ox potential and high specific capacity offer great promise to the development of high energy density lithium-based...

  5. High Energy Density and High Temperature Multilayer Capacitor Films for Electric Vehicle Applications

    Science.gov (United States)

    Treufeld, Imre; Song, Michelle; Zhu, Lei; Baer, Eric; Snyder, Joe; Langhe, Deepak

    2015-03-01

    Multilayer films (MLFs) with high energy density and high temperature capability (>120 °C) have been developed at Case Western Reserve University. Such films offer a potential solution for electric car DC-link capacitors, where high ripple currents and high temperature tolerance are required. The current state-of-the-art capacitors used in electric cars for converting DC to AC use biaxially oriented polypropylene (BOPP), which can only operate at temperatures up to 85 °C requiring an external cooling system. The polycarbonate (PC)/poly(vinylidene fluoride) (PVDF) MLFs have a higher permittivity compared to that of BOPP (2.3), leading to higher energy density. They have good mechanical stability and reasonably low dielectric losses at 120 °C. Nonetheless, our preliminary dielectric measurements show that the MLFs exhibit appreciable dielectric losses (20%) at 120 °C, which would, despite all the other advantages, make them not suitable for practical applications. Our preliminary data showed that dielectric losses of the MLFs at 120 °C up to 400 MV/m and 1000 Hz originate mostly from impurity ionic conduction. This work is supported by the NSF PFI/BIC Program (IIP-1237708).

  6. Oil-sealed femtoliter fiber-optic arrays for single molecule analysis.

    Science.gov (United States)

    Zhang, Huaibin; Nie, Shuai; Etson, Candice M; Wang, Raymond M; Walt, David R

    2012-06-21

    This paper describes a novel method for fabricating and sealing high-density arrays of femtoliter reaction chambers. We chemically etch one end of a 2.3 mm diameter glass optical fiber bundle to create an array of microwells. We then use a contact printing method to selectively modify the surface of the material between microwells with a hydrophobic silane. This modification makes it possible to fill the wells with aqueous solution and then seal them with a droplet of oil, forming an array of isolated reaction chambers. Individual β-galactosidase molecules trapped in these reaction chambers convert a substrate into a fluorescent product that can be readily detected because a high local concentration of product is achieved. This binary readout can be used for ultra-sensitive measurements of enzyme concentration. We observed that the percentage of wells showing enzyme activity was linearly dependent on the concentration of soluble β-galactosidase in the picomolar range. A similar response was also observed for streptavidin-β-galactosidase captured by biotinylated beads. These arrays are also suitable for performing single-molecule kinetics studies on hundreds to thousands of enzyme molecules simultaneously. We observed a broad distribution of catalytic rates for individual β-galactosidase molecules trapped in the microwells, in agreement with previous studies using similar arrays that were mechanically sealed. We have further demonstrated that this femtoliter fiber-optic array can be integrated into a PDMS microfluidic channel system and sealed with oil on-chip, creating an easy to use and high-throughput device for single-molecule analysis.

  7. Oil-sealed femtoliter fiber-optic arrays for single molecule analysis†‡

    Science.gov (United States)

    Zhang, Huaibin; Nie, Shuai; Etson, Candice M.; Wang, Raymond M.

    2012-01-01

    This paper describes a novel method for fabricating and sealing high-density arrays of femtoliter reaction chambers. We chemically etch one end of a 2.3 mm diameter glass optical fiber bundle to create an array of microwells. We then use a contact printing method to selectively modify the surface of the material between microwells with a hydrophobic silane. This modification makes it possible to fill the wells with aqueous solution and then seal them with a droplet of oil, forming an array of isolated reaction chambers. Individual β-galactosidase molecules trapped in these reaction chambers convert a substrate into a fluorescent product that can be readily detected because a high local concentration of product is achieved. This binary readout can be used for ultra-sensitive measurements of enzyme concentration. We observed that the percentage of wells showing enzyme activity was linearly dependent on the concentration of soluble β-galactosidase in the picomolar range. A similar response was also observed for streptavidin-β-galactosidase captured by biotinylated beads. These arrays are also suitable for performing single-molecule kinetics studies on hundreds to thousands of enzyme molecules simultaneously. We observed a broad distribution of catalytic rates for individual β-galactosidase molecules trapped in the microwells, in agreement with previous studies using similar arrays that were mechanically sealed. We have further demonstrated that this femtoliter fiber-optic array can be integrated into a PDMS microfluidic channel system and sealed with oil on-chip, creating an easy to use and high-throughput device for single-molecule analysis. PMID:22311152

  8. Constraining cloud parameters using high density gas tracers in galaxies

    CERN Document Server

    Kazandjian, M V; Meijerink, R; Israel, F P; Coppola, C M; Rosenberg, M J F; Spaans, M

    2016-01-01

    Far-infrared molecular emission is an important tool used to understand the excitation mechanisms of the gas in the inter-stellar medium of star-forming galaxies. In the present work, we model the emission from rotational transitions with critical densities n >~ 10^4 cm-3. We include 4-3 ~ 30 in order to obtain significant emission from n > 10^4 cm-3 gas. Such Mach numbers are expected in star-forming galaxies, LIRGS, and ULIRGS. By fitting line ratios of HCN(1-0), HNC(1-0), and HCO+(1-0) for a sample of LIRGS and ULIRGS using mechanically heated PDRs, we constrain the Mach number of these galaxies to 29 < M < 77.

  9. Hard Loops, Soft Loops, and High Density Effective Field Theory

    CERN Document Server

    Schäfer, T

    2003-01-01

    We study several issues related to the use of effective field theories in QCD at large baryon density. We show that the power counting is complicated by the appearance of two scales inside loop integrals. Hard dense loops involve the large scale $mu^2$ and lead to phenomena such as screening and damping at the scale $gmu$. Soft loops only involve small scales and lead to superfluidity and non-Fermi liquid behavior at exponentially small scales. Four-fermion operators in the effective theory are suppressed by powers of $1/mu$, but they get enhanced by hard loops. As a consequence their contribution to the pairing gap is only suppressed by powers of the coupling constant, and not powers of $1/mu$. We determine the coefficients of four-fermion operators in the effective theory by matching quark-quark scattering amplitudes. Finally, we introduce a perturbative scheme for computing corrections to the gap parameter in the superfluid phase

  10. High Energy Density Physics:. the Laser Field of Tomorrow

    Science.gov (United States)

    Freeman, Richard R.

    2013-03-01

    Ever since its invention, the laser has become an increasingly important tool for physics research. Indeed, the laser has made it possible to not only study many extant physical phenomena, but also to actually produce matter in conditions that don't exist in nature, or more precisely, don't exist on the earth. In this lecture, I discuss how the development of lasers that produce ultra-short (˜fsec) and ultra-intense (≥1020 W/cm2) laser pulses actually produce plasmas that are at a density and temperature that exist only in stars. In doing so I discuss some of the basics of these extreme pulses interacting with electrons, yielding surprisingly intriguing physical phenomena. Finally, I argue that this field is an essential element in any comprehensive physical research endeavor, explicitly citing its fundamental relationship with the development of clean, unlimited fusion energy power.

  11. Multiscale functional connectivity estimation on low-density neuronal cultures recorded by high-density CMOS Micro Electrode Arrays.

    Science.gov (United States)

    Maccione, Alessandro; Garofalo, Matteo; Nieus, Thierry; Tedesco, Mariateresa; Berdondini, Luca; Martinoia, Sergio

    2012-06-15

    We used electrophysiological signals recorded by CMOS Micro Electrode Arrays (MEAs) at high spatial resolution to estimate the functional-effective connectivity of sparse hippocampal neuronal networks in vitro by applying a cross-correlation (CC) based method and ad hoc developed spatio-temporal filtering. Low-density cultures were recorded by a recently introduced CMOS-MEA device providing simultaneous multi-site acquisition at high-spatial (21 μm inter-electrode separation) as well as high-temporal resolution (8 kHz per channel). The method is applied to estimate functional connections in different cultures and it is refined by applying spatio-temporal filters that allow pruning of those functional connections not compatible with signal propagation. This approach permits to discriminate between possible causal influence and spurious co-activation, and to obtain detailed maps down to cellular resolution. Further, a thorough analysis of the links strength and time delays (i.e., amplitude and peak position of the CC function) allows characterizing the inferred interconnected networks and supports a possible discrimination of fast mono-synaptic propagations, and slow poly-synaptic pathways. By focusing on specific regions of interest we could observe and analyze microcircuits involving connections among a few cells. Finally, the use of the high-density MEA with low density cultures analyzed with the proposed approach enables to compare the inferred effective links with the network structure obtained by staining procedures.

  12. Murray secretion scale and fiberoptic endoscopic evaluation of swallowing in predicting aspiration in dysphagic patients.

    Science.gov (United States)

    Kuo, Chia-Wei; Allen, Clint Tanner; Huang, Chu-Chun; Lee, Chia-Jung

    2017-06-01

    The objective of this retrospective review is to evaluate the ability of the Murray secretion scale to predict aspiration as determined by fiberoptic endoscopic evaluation of swallowing. Patients with dysphagia undergoing a fiberoptic endoscopic evaluation of swallowing study between January 2013 and November 2015 from a single, tertiary care institution were retrospectively reviewed. The Murray secretion scale and penetration aspiration scale on fiberoptic endoscopic evaluation of swallowing examination were determined. Spearman's correlation analysis, sensitivity, specificity, predictive values, and relative risk evaluating the relationship between the Murray secretion scale and aspiration on fiberoptic endoscopic evaluation of swallowing were calculated. Subgroups of head and neck cancer patients, penetration group, and aspiration group were also analyzed. The mean age of the cases (N = 212) was 62.4 years. Eighty percent were male. There was a strong correlation between Murray secretion scale grade and penetration aspiration scale score (r = 0.785, p Murray secretion scale grade 2 or higher in predicting aspiration were 74 and 90%, respectively. Individuals with a Murray secretion scale grade of 2 or higher were 13.6 times more likely to aspirate than patients with a lower Murray secretion scale grade. All subgroups showed similar trend. Determination of a Murray secretion scale grade, determined by flexible nasopharyngoscopy, may predict patients at high risk for aspiration. In clinical scenarios where more complete assessments of aspiration risk are immediately impossible or impractical, the Murray secretion scale grade may add valuable information to assist in clinical decision-making in patients with dysphagia.

  13. High performance power-configurable preamplifier in a high-density paralleloptical receiver

    Institute of Scientific and Technical Information of China (English)

    Wang Xiaoxia; Wang Zhigong

    2012-01-01

    A power-configurable high performance preamplifier was implemented in standard 180-nm CMOS technology for 12 × 10 Gb/s high-density ultra-high speed parallel optical communication system.With critical limitations on power consumption,area and fabrication cost,the preamplifier achieves high performance,e.g.high bandwidth,high trans-impedance gain,low noise and high stability.A novel feed-forward common gate (FCG)stage is adopted to alleviate contradictions on trans-impedance gain and bandwidth by using a low headroom consuming approach to isolate a large input capacitance and using complex pole peaking techniques to substitute inductors to achieve bandwidth extension.A multi-supply power-configurable scheme was employed to avoid wasteful power caused by a pessimistic estimation of process-voltage-temperature (PVT) variation.Two representative samples provide a trans-impedance gain of 53.9 dBΩ,a 3-dB bandwidth of 6.8 GHz,a power dissipation of 6.26 mW without power-configuration and a trans-impedance gain of 52.1 dBΩ,a 3-dB bandwidth of 8.1 GHz,a power dissipation of 6.35 mW with power-configuration,respectively.The measured average input-referred noise-current spectral density is no more than 28 pA/√Hz.The chip area is only 0.08 × 0.08 mm2.

  14. Particle control in high power, high density long pulse operation on Tore Supra

    Energy Technology Data Exchange (ETDEWEB)

    Bucalossi, J.; Brosset, C.; Dufour, E.; Loarer, T.; Monier-Garbet, P.; Pegourie, B.; Tsitrone, E.; Basiuk, V.; Bremond, S.; Chantant, M.; Colas, L.; Commaux, N.; Geraud, A.; Guirlet, R.; Gunn, J.; Hertout, P.; Hoang, G. T.; Kazarian, F.; Mazon, D.; Maget, P.; Mitteau, R.; Moreau, P.; Saint-Laurent, F.; Schunke, B.; Vallet, J. C.

    2005-07-01

    Long pulse operation, and the related issues such as non inductive current drive, particle control and power exhaust, is a crucial point to investigate for next step machines. In the Tore Supra tokamak, equipped with superconducting magnets and actively cooled plasma facing components discharge up to 6 minutes, coupling 1 GJ of energy to the plasma, have already been obtained with 3 MW of LHCD at low density (%50 n{sub C}W). A new scenario has been recently developed combining ICRH and LHCD up to a total power of 8.5 MW at high density (90% n{sub G}W), limited in time to 60 s by the capability of the ICRH heating systems (500 MJ of injected/extracted energy). This paper describes the new operating conditions and compares the results obtained in both scenarios with a special focus on particle control. The density is still maintained by a feedback loop on the gas injection system and do not exhibit any uncontrolled excursions. The radiated power fraction is stable and remains below 30% all along the discharges. In comparison with the previous low density long duration discharges, the gas injection rate necessary to maintain the stationary plasma density is increased by a factor up to 3. The edge electron temperature and density measured by a reciprocating probes are also significantly different, signifying as expected a higher recycling flux. On the other hand, particle balance analyses based on pressure measurements show that the absolute in vessel retention rate is roughly equivalent in both scenarios. This indicates that the retention mechanisms could be dominated by wall processes such as diffusion in carbon porosities rather than plasma processes, dependent on edge conditions, such as codeposition. Moreover, analysis of carbon deposits originating from different locations inside the vessel reveal relatively low deuterium content, unable to account for the large deuterium in-vessel retention worked out from particle balance. Finally, particle control with more

  15. Development and Testing of a Post-Installable Deepwater Monitoring System Using Fiber-Optic Sensors

    Science.gov (United States)

    Seaman, Calvin H.; Brower, David V.; Le, Suy Q.; Tang, Henry H.

    2015-01-01

    This paper addresses the design and development of a fiber-optic monitoring system that can be deployed on existing deepwater risers and flowlines; and provides a summary of test article fabrication and the subsequent laboratory testing performed at the National Aeronautics and Space Administration-Johnson Space Center (NASA-JSC). A major challenge of a post-installed instrumentation system is to ensure adequate coupling between the instruments and the riser or flowline of interest. This work investigates the sensor coupling for pipelines that are suspended in a water column (from topside platform to seabed) using a fiber-optic sensor clamp and subsea bonding adhesive. The study involved the design, fabrication, and test of several prototype clamps that contained fiber-optic sensors. A mold was produced by NASA using 3-D printing methods that allowed the casting of polyurethane clamp test articles to accommodate 4-inch and 8-inch diameter pipes. The prototype clamps were installed with a subsea adhesive in a "wet" environment and then tested in the NASA Structures Test Laboratory (STL). The tension, compression, and bending test data showed that the prototype sensor clamps achieved good structural coupling, and could provide high quality strain measurement for active monitoring.

  16. Influence of PDMS encapsulation on the sensitivity and frequency range of fiber-optic interferometer

    Science.gov (United States)

    Nedoma, Jan; Fajkus, Marcel; Vasinek, Vladimir

    2016-10-01

    Fiber-optic sensors are one of the dynamically developing areas of photonics and photonic applications. This group of sensors can also include fiber-optic interferometers which enable very sensitive sensing. They are entirely passive regarding power supply, and immune to electromagnetic interference. This type of sensor is dependent on the phase change. It mostly used in the field which requires high measurement accuracy. We can achieve a change of sensitivity in the order of 10-8. The fundamental problem of fiber-optic interferometry is a design and imposition (encapsulation) of the measuring arm and reference arm of the interferometer. Polydimethylsiloxane elastomer (PDMS) is one of the possibilities to encapsulation of the sensory arm. Two-component PDMS Sylgard 184 is used type. The article analyzes the effect of encapsulation into a PDMS of the measuring arm of the interferometer to frequency response and sensitivity of the Mach-Zehnder interferometer with the division of power in a ratio of 1:1 (measuring arm and reference arm). Input power set to a reference value of 1 mW, this value was constant for all performed experimental measurements. The generator of a harmonic signal with fixed amplitude signal used for analysis of the frequency characteristic of the interferometer. The application written in LabView development environment, evaluated the amplitude-frequency spectra of the signal. Repeated test of assembled prototype verified the measured results.

  17. High-density lipoprotein particles, coronary heart disease, and niacin

    Science.gov (United States)

    In clinical trials, the use of statins in patients with high risk for cardiovascular disease (CVD) has resulted in a 25% to 40% decrease in major clinical events. However, despite a marked reduction (up to 60%) in LDL-C, approximately 50% (or more) of patients continue to have CVD events. This high ...

  18. Density-based retrieval from high-similarity image databases

    DEFF Research Database (Denmark)

    Hansen, Michael Edberg; Carstensen, Jens Michael

    2004-01-01

    Many image classification problems can fruitfully be thought of as image retrieval in a "high similarity image database" (HSID) characterized by being tuned towards a specific application and having a high degree of visual similarity between entries that should be distinguished. We introduce...

  19. High critical current densities in industrial scale composites made from high homogeneity NB 46. 5 TI

    Energy Technology Data Exchange (ETDEWEB)

    Larbalestier, D.C.; Hemachalam, K.; Lee, P.; McDonald, W.K.; O' Larey, P.; Scanlan, R.; Starch, W.; Taylor, C.; Warnes, W.; West, A.W.; Zeitlin, B.

    1985-03-01

    Recent work in our group on the fabricationmicrostructure-superconducting properties of composites of Nb-Ti has produced much new information about the precipitate morphology and origins of high critical current density (J /SUB c/ ) in these materials./sup 1 -4/ Precipitation of Ti-rich phase is seen to commence as a grain boundary film 2 - 4 nm thick, the film then developing into approximately equiaxed particles of ..cap alpha..-Ti at the boundary triple points. The typical size of such precipitates is 50 - 100 nm. Controlled drawing of such a structure produces an array of locally ordered ribbon precipitates. These precipitates are typically 3 - 5 nm thick by 100 - 300 nm long (when observed in transverse section). Their length in longitudinal section appears to be several hundred nm, indicating great ductility in these small ..cap alpha..-Ti precipitates. The typical separation of the precipitates is 20 - 30 nm. Thus the dimensions of the precipitate array are quite comparable to that of the flux lattice since the fluxoid separation is 22 nm at 5 T and the fluxoid diameter of Nb 46.5 wt% Ti is approximately 10 nm. The flux pinning behavior of these precipitate structures is expected to be complex: /SUP 2.4/ the defect density is very high, the precipitate morphology has a very high aspect ratio and the extreme thinness of the precipitates must permit some superconductivity to be induced in them by the proximity effect./sup 5/

  20. High-density operation of the Proto-MPEX High Intensity Plasma Source

    Science.gov (United States)

    Caughman, J. B. O.; Goulding, R. H.; Biewer, T. M.; Bigelow, T. S.; Campbell, I. H.; Caneses, J.; Diem, S. J.; Martin, E. H.; Parish, C. M.; Rapp, J.; Ray, H. B.; Shaw, G. C.; Showers, M. A.; Donovan, D.; Piotrowicz, P. A.; Martin, D. C.

    2016-10-01

    The Prototype Materials Plasma Experiment (Proto-MPEX) is a linear high-intensity RF plasma source that combines a high-density helicon plasma generator with ion and electron heating sections. It is being used to study the physics of heating over-dense plasmas in a linear configuration with the goal of delivering a plasma heat flux of 10 MW/m2 at a target. The helicon plasma is produced by coupling 13.56 MHz RF power at levels of >100 kW. A 30 kW ion cyclotron antenna has recently been installed, and microwaves at 28 GHz ( 150 kW) are coupled to the electrons in the over-dense helicon plasma via Electron Bernstein Waves (EBW). High plasma densities near the target have been produced in D ( 5 x1019/m3) , and electron temperatures range from 3 to >10 eV, depending on the source parameters. IR camera images of the target plate indicate plasma heat depositions >10 MW/m2 for some operating conditions. Details of the experimental results of the operational domain with respect to Te and ne as well as results from initial plasma material interaction tests will be presented. ORNL is managed by UT-Battelle, LLC, for the U.S. DOE under contract DE-AC-05-00OR22725.

  1. Kaon condensation in neutron stars and high density behaviour of nuclear symmetry energy

    CERN Document Server

    Kubis, S

    1999-01-01

    We study the influence of a high density behaviour of the nuclear symmetry energy on a kaon condensation in neutron stars. We find that the symmetry energy typical for several realistic nuclear potentials, which decreases at high densities, inhibits kaon condensation for weaker kaon-nucleon couplings. There exists a threshold coupling above which the kaon condensate forms at densities exceeding some critical value. This is in contrast to the case of rising symmetry energy, as e.g. for relativistic mean field models, when the kaon condensate can form for any coupling at a sufficiently high density. Properties of the condensate are also different in both cases.

  2. High current density sheet-like electron beam generator

    Science.gov (United States)

    Chow-Miller, Cora; Korevaar, Eric; Schuster, John

    Sheet electron beams are very desirable for coupling to the evanescent waves in small millimeter wave slow-wave circuits to achieve higher powers. In particular, they are critical for operation of the free-electron-laser-like Orotron. The program was a systematic effort to establish a solid technology base for such a sheet-like electron emitter system that will facilitate the detailed studies of beam propagation stability. Specifically, the effort involved the design and test of a novel electron gun using Lanthanum hexaboride (LaB6) as the thermionic cathode material. Three sets of experiments were performed to measure beam propagation as a function of collector current, beam voltage, and heating power. The design demonstrated its reliability by delivering 386.5 hours of operation throughout the weeks of experimentation. In addition, the cathode survived two venting and pump down cycles without being poisoned or losing its emission characteristics. A current density of 10.7 A/sq cm. was measured while operating at 50 W of ohmic heating power. Preliminary results indicate that the nearby presence of a metal plate can stabilize the beam.

  3. Investigation of heavy current discharges with high initial gas density

    Energy Technology Data Exchange (ETDEWEB)

    Budin, A.; Bogomaz, A.; Kolikov, V.; Kuprin, A.; Leontiev, V.; Rutberg, P.; Shirokov, N. [Institute of Problems of Electrophysics of Russian Academy of Sciences, Dvortsovayanab., 18, St. Petersburg, 191065 (Russia)

    1996-05-01

    Piezoelectric pressure transducers, with noise immunity and time resolution of 0,5 {mu}s were used to measure pulse pressures of 430 MPa along the axis of an electrical discharge channel. Initial concentration of He was 2,7{center_dot}10{sup 21}cm{sup {minus}3}, dI/dt=6{center_dot}10{sup 11}A/s, and I{sub max}=560kA. Shock waves with amplitudes exceeding the pressure along the axis, were detected by a pressure transducer on the wall of the discharge chamber. Typical shock velocities were 2{center_dot}4km/s. Average pressure measurements along the discharge axis at different radii were used to estimate the current density distribution along the canal radius. The presence of the shock waves, promoting the additional hydrogen heating in the discharge chamber, has been registered during the discharge in hydrogen for I{sub max}{approximately}1MA and an initial concentration of 10{sup 21}cm{sup {minus}3}. {copyright} {ital 1996 American Institute of Physics.}

  4. High current density contacts for photoconductive semiconductor switches

    Energy Technology Data Exchange (ETDEWEB)

    Baca, A.G.; Hjalmarson, H.P.; Loubriel, G.M.; McLaughlin, D.L.; Zutavern, F.J.

    1993-08-01

    The current densities implied by current filaments in GaAs photoconductive semiconductor switches (PCSS) are in excess of 1 MA/cm{sup 2}. As the lateral switches are tested repeatedly, damage accumulates at the contacts until electrical breakdown occurs across the surface of the insulating region. In order to improve the switch lifetime, the incorporation of n- and p-type ohmic contacts in lateral switches as well as surface geometry modifications have been investigated. By using p-type AuBe ohmic contacts at the anode and n-type AuGe ohmic contacts at the cathode, contact lifetime improvements of 5--10x were observed compared to switches with n-type contacts at both anode and cathode. Failure analysis on samples operated for 1--1,000 shots show that extensive damage still exists for at least one contact on all switches observed and that temperatures approaching 500{degrees}C are can be reached. However, the n-type AuGe cathode is often found to have no damage observable by scanning electron microscopy (SEM). The observed patterns of contact degradation indicate directions for future contact improvements in lateral switches.

  5. High Energy Density Lithium Air Batteries for Oxygen Concentrators Project

    Data.gov (United States)

    National Aeronautics and Space Administration — For NASA's Exploration Medical Capabilities mission, extremely high specific energy power sources, with specific energy over 2000 Wh/kg, are urgently sought after....

  6. Fabrication of very-low-density, high-stiffness carbon fiber/aluminum hybridized composite with ultra-low density and high stiffness (M-11)

    Science.gov (United States)

    Suzuki, Tomoo

    1993-01-01

    Fabrication of a composite material with ultra-low density and high stiffness in microgravity is the objective of the investigation. The composite structure to be obtained is a random three-dimensional array of high modulus, short carbon fibers bonded at contact points by an aluminum alloy coated on the fibers. The material is highly porous and thus has a very low density. The motivation toward the investigation, simulation experiments, choice of the component materials, and on-flight experiment during ballistic trajectory of a NASDA rocket, are described.

  7. Experiment to measure oxygen opacity at high density and temperature

    Science.gov (United States)

    Keiter, Paul; Mussack, Katie; Orban, Chris; Colgan, James; Ducret, Jean-Eric; Fontes, Christopher J.; Guzik, Joyce Ann; Heeter, Robert F.; Kilcrease, Dave; Le Pennec, Maelle; Mancini, Roberto; Perry, Ted; Turck-Chièze, Sylvaine; Trantham, Matt

    2017-06-01

    In recent years, there has been a debate over the abundances of heavy elements (Z >2) in the solar interior. Recent solar atmosphere models [Asplund 2009] find a significantly lower abundance for C, N, and O compared to models used roughly a decade ago. This discrepancy has led to an investigation of opacities through laboratory experiments and improved opacity models for many of the larger contributors to the sun’s opacity, including iron and oxygen. Recent opacity measurements of iron disagree with opacity model predictions [Bailey et al, 2015]. Although these results are still controversial, repeated scrutiny of the experiment and data has not produced a conclusive reason for the discrepancy. New models have been implemented in the ATOMIC opacity code for C, O and Fe to address the solar abundance issue [Colgan, 2013]. Armstrong et al [2014] have also implemented changes in the ATOMIC code for low-Z elements. However, no data currently exists to test the low-Z material models in the regime relevant to the solar convection zone. We present an experimental design using the opacity platform developed at the National Ignition Facility to study the oxygen opacity at densities and temperatures near the solar convection zone conditions.This work is funded by the U.S. DOE, through the NNSA-DS and SC-OFES Joint Program in HEDPLP, grant No. DE-NA0001840, and the NLUF Program, grant No. DE-NA0000850, and through LLE, University of Rochester by the NNSA/OICF under Agreement No. DE-FC52-08NA28302.

  8. High power density self-cooled lithium-vanadium blanket.

    Energy Technology Data Exchange (ETDEWEB)

    Gohar, Y.; Majumdar, S.; Smith, D.

    1999-07-01

    A self-cooled lithium-vanadium blanket concept capable of operating with 2 MW/m{sup 2} surface heat flux and 10 MW/m{sup 2} neutron wall loading has been developed. The blanket has liquid lithium as the tritium breeder and the coolant to alleviate issues of coolant breeder compatibility and reactivity. Vanadium alloy (V-4Cr-4Ti) is used as the structural material because it can accommodate high heat loads. Also, it has good mechanical properties at high temperatures, high neutron fluence capability, low degradation under neutron irradiation, good compatibility with the blanket materials, low decay heat, low waste disposal rating, and adequate strength to accommodate the electromagnetic loads during plasma disruption events. Self-healing electrical insulator (CaO) is utilized to reduce the MHD pressure drop. A poloidal coolant flow with high velocity at the first wall is used to reduce the peak temperature of the vanadium structure and to accommodate high surface heat flux. The blanket has a simple blanket configuration and low coolant pressure to reduce the fabrication cost, to improve the blanket reliability, and to increase confidence in the blanket performance. Spectral shifter, moderator, and reflector are utilized to improve the blanket shielding capability and energy multiplication, and to reduce the radial blanket thickness. Natural lithium is used to avoid extra cost related to the lithium enrichment process.

  9. Heating and Life Problem of High Power Density Induction Motor

    Institute of Scientific and Technical Information of China (English)

    李立毅; 崔淑梅; 宋立伟; 胡余生

    2004-01-01

    An induction motor with its speed modulated by frequency features wide transfer speed range, high systematic efficiency, simple structure and long life, and it therefore becomes one of the best driving motors used in electrical vehicles. The present research trend of it is high power, high speed, high efficiency and long life. How to meet the above requirements by using the electromagnetic design, structure design and heat design, becomes a matter that needs to be resolved now. In this paper, the characters of the motor in operation are analyzed, all kinds of factors that relate to life are laid out, its heating and loss are discussed and analyzed.The key reasons affecting the motor life are presented, and different characters of a high induction motor are compared with these of a general induction motor. A design idea is described, that is: we should consider how to improve the efficiency and reliability as well as how to reduce the heating by changing the electromagnet,structure, dissipation and operation of the motor. How to reduce its losses and to improve its dissipation has been presented in the paper.

  10. High power density self-cooled lithium-vanadium blanket.

    Energy Technology Data Exchange (ETDEWEB)

    Gohar, Y.; Majumdar, S.; Smith, D.

    1999-07-01

    A self-cooled lithium-vanadium blanket concept capable of operating with 2 MW/m{sup 2} surface heat flux and 10 MW/m{sup 2} neutron wall loading has been developed. The blanket has liquid lithium as the tritium breeder and the coolant to alleviate issues of coolant breeder compatibility and reactivity. Vanadium alloy (V-4Cr-4Ti) is used as the structural material because it can accommodate high heat loads. Also, it has good mechanical properties at high temperatures, high neutron fluence capability, low degradation under neutron irradiation, good compatibility with the blanket materials, low decay heat, low waste disposal rating, and adequate strength to accommodate the electromagnetic loads during plasma disruption events. Self-healing electrical insulator (CaO) is utilized to reduce the MHD pressure drop. A poloidal coolant flow with high velocity at the first wall is used to reduce the peak temperature of the vanadium structure and to accommodate high surface heat flux. The blanket has a simple blanket configuration and low coolant pressure to reduce the fabrication cost, to improve the blanket reliability, and to increase confidence in the blanket performance. Spectral shifter, moderator, and reflector are utilized to improve the blanket shielding capability and energy multiplication, and to reduce the radial blanket thickness. Natural lithium is used to avoid extra cost related to the lithium enrichment process.

  11. On The Use Of High-Density Rock In Rubble Mound Breakwaters

    DEFF Research Database (Denmark)

    Helgason, Einar; Burcharth, H. F.

    2005-01-01

    Natural rock with high density is widely used in the Scandinavian countries. However, the use of natural rock with density higher than 2:9t=m3 is ordinarily associated with some kind of problem solving, e.g. where normal density stones have to be replaced with heavier stones without increasing...... the construction volume or layer thickness. Most common design formulae do not give a clear conclusion on the in°uence of the rock density on the stability. The present paper presents results of small and large scale model tests in which is used rock with different densities. It is shown that the positive effect...

  12. High Energy Density Battery Lithium Thionyl Chloride Improved Reverse Voltage Design.

    Science.gov (United States)

    1981-12-01

    BATTERY LITHIUM THIONYL CHLORIDE IMPROVED R-ETC(U) DEC 81 A E ZOLLA N660011-C-0310...HIGH ENERGY DENSITY BATTERY LITHIUM THIONYL CHLORIDE IMPROVED REVERSE VOLTAGE DESIGN Dr. A. E. Zolla Altus Corporation C:1 1610 Crane Court San Jose...reverse aide If necesary and identify by block number) Lithium Battery Lithium Thionyl Chloride High Energy Density Battery Voltage Reversal Battery

  13. Low voltage electroosmotic pump for high density integration into microfabricated fluidic systems

    NARCIS (Netherlands)

    Heuck, F.C.A.; Staufer, U.

    2011-01-01

    A low voltage electroosmotic (eo) pump suitable for high density integration into microfabricated fluidic systems has been developed. The high density integration of the eo pump required a small footprint as well as a specific on-chip design to ventilate the electrolyzed gases emerging at the platin

  14. Maize canopy architecture and adaptation to high plant density in long term selection programs

    Science.gov (United States)

    Grain yield since the 1930s has increased more than five-fold in large part due to improvements in adaptation to high plant density. Changes to plant architecture that associated with improved light interception have made a major contribution to improved adaptation to high plant density. Improved ...

  15. Density-based retrieval from high-similarity image databases

    DEFF Research Database (Denmark)

    Hansen, Michael Edberg; Carstensen, Jens Michael

    2004-01-01

    Many image classification problems can fruitfully be thought of as image retrieval in a "high similarity image database" (HSID) characterized by being tuned towards a specific application and having a high degree of visual similarity between entries that should be distinguished. We introduce...... a method for HSID retrieval using a similarity measure based on a linear combination of Jeffreys-Matusita distances between distributions of local (pixelwise) features estimated from a set of automatically and consistently defined image regions. The weight coefficients are estimated based on optimal...... retrieval performance. Experimental results on the difficult task of visually identifying clones of fungal colonies grown in a petri dish and categorization of pelts show a high retrieval accuracy of the method when combined with standardized sample preparation and image acquisition....

  16. High-resolution 17-75 keV backlighters for high energy density experiments

    Science.gov (United States)

    Park, H.-S.; Maddox, B. R.; Giraldez, E.; Hatchett, S. P.; Hudson, L. T.; Izumi, N.; Key, M. H.; Le Pape, S.; MacKinnon, A. J.; MacPhee, A. G.; Patel, P. K.; Phillips, T. W.; Remington, B. A.; Seely, J. F.; Tommasini, R.; Town, R.; Workman, J.; Brambrink, E.

    2008-07-01

    17-75keV one- and two-dimensional high-resolution (1017W /cm2. High-resolution point projection one- and two-dimensional radiography has been achieved using microfoil and microwire targets attached to low-Z substrate materials. The microwire size was 10μm×10μm×300μm on a 300μm×300μm×5μm polystyrene substrate. The radiography experiments were performed using the Titan laser at Lawrence Livermore National Laboratory. The results show that the resolution is dominated by the microwire target size and there is very little degradation from the plasma plume, implying that the high-energy x-ray photons are generated mostly within the microwire volume. There are enough Kα photons created with a 300J, 1-ω, 40ps pulse laser from these small volume targets, and that the signal-to-noise ratio is sufficiently high, for single shot radiography experiments. This unique technique will be used on future high energy density experiments at many new high-power laser facilities.

  17. High precision (14 bit), high density (octal) analog to digital converter for spectroscopy applications

    Science.gov (United States)

    Subramaniam, E. T.; Jain, Mamta; Bhowmik, R. K.; Tripon, Michel

    2008-10-01

    Nuclear and particle physics experiments with large number of detectors require signal processing and data collection strategies that call for the ability to collect large amount of data while not sacrificing the precision and accuracy of the data being collected. This paper deals with the development of a high precision pulse peak detection, analog to digital converter (ADC) module with eight independent channels in plug-in daughter card motherboard model, best suited for spectroscopy experiments. This module provides multiple channels without cross-talk and of 14 bit resolution, while maintaining high density (each daughter card has an area of just 4.2″×0.51″) and exhibiting excellent integral nonlinearity (≤±2 mV or ±0.02% full scale reading) and differential nonlinearity (≤±1%). It was designed, developed and tested, in house, and gives added advantages of cost effectiveness and ease of maintenance.

  18. Exploration of highly accelerated magnetic resonance elastography using high-density array coils

    Science.gov (United States)

    Bosshard, John C.; Yallapragada, Naresh; McDougall, Mary P.

    2017-01-01

    Background Magnetic resonance elastography (MRE) measures tissue mechanical properties by applying a shear wave and capturing its propagation using magnetic resonance imaging (MRI). By using high density array coils, MRE images are acquired using single echo acquisition (SEA) and at high resolutions with significantly reduced scan times. Methods Sixty-four channel uniplanar and 32×32 channel biplanar receive arrays are used to acquire MRE wave image sets from agar samples containing regions of varying stiffness. A mechanical actuator triggered by a stepped delay time introduces vibrations into the sample while a motion sensitizing gradient encodes micrometer displacements into the phase. SEA imaging is used to acquire each temporal offset in a single echo, while multiple echoes from the same array are employed for highly accelerated imaging at high resolutions. Additionally, stiffness variations as a function of temperature are studied by using a localized heat source above the sample. A custom insertable gradient coil is employed for phase compensation of SEA imaging with the biplanar array to allow imaging of multiple slices. Results SEA MRE images show a mechanical shear wave propagating into and across agar samples. A set of 720 images was obtained in 720 echoes, plus a single reference scan for both harmonic and transient MRE. A set of 2,950 wave image frames was acquired from pairs of SEA images captured during heating, showing the change in mechanical wavelength with the change in agar properties. A set of 240 frames was acquired from two slices simultaneously using the biplanar array, with phase images processed into displacement maps. Combining the narrow sensitivity patterns and SNR advantage of the SEA array coil geometry allowed acquisition of a data set with a resolution of 156 µm × 125 µm × 1,000 µm in only 64 echoes, demonstrating high resolution and high acceleration factors. Conclusions MRE using high-density arrays offers the unique ability

  19. High-Density Noncovalent Functionalization of DNA by Electrostatic Interactions

    NARCIS (Netherlands)

    Chen, Wei; Gerasimov, Jennifer Y; Zhao, Pei; Liu, Kai; Herrmann, Andreas

    2015-01-01

    Preserving DNA hybridization in organic solvents could someday serve to significantly extend the applicability of DNA-based technologies. Here, we present a method that can be used to solubilize double-stranded DNA at high concentrations in organic media. This method requires first precipitating a

  20. Processor for high-density digital tape-recorded signals

    Science.gov (United States)

    Ashlock, J. C.

    1973-01-01

    Linear filter and detection theory can bear on problem of reconstructing recorded bit stream. Problem can be taken from realm of nonlinear problems even though basic record process is still recognized as highly nonlinear. Digital tape recorder can be modeled as particular type of linear communication channel with intersymbol interference.

  1. Tree filtering for high density airborne LiDAR data

    NARCIS (Netherlands)

    Abd Rahman, M.Z.; Gorte, B.G.H.

    2008-01-01

    A high resolution Airborne LiDAR data creates better opportunity for an individual tree measurement and provides valuable results for more precise forest inventory. This paper presents tree filtering approach that able to separate dominant tree and undergrowth vegetation. The results can be used for

  2. High energy density battery based on complex hydrides

    Science.gov (United States)

    Zidan, Ragaiy

    2016-04-26

    A battery and process of operating a battery system is provided using high hydrogen capacity complex hydrides in an organic non-aqueous solvent that allows the transport of hydride ions such as AlH.sub.4.sup.- and metal ions during respective discharging and charging steps.

  3. High energy density battery based on complex hydrides

    Energy Technology Data Exchange (ETDEWEB)

    Zidan, Ragaiy

    2016-04-26

    A battery and process of operating a battery system is provided using high hydrogen capacity complex hydrides in an organic non-aqueous solvent that allows the transport of hydride ions such as AlH.sub.4.sup.- and metal ions during respective discharging and charging steps.

  4. Tree filtering for high density airborne LiDAR data

    NARCIS (Netherlands)

    Abd Rahman, M.Z.; Gorte, B.G.H.

    2008-01-01

    A high resolution Airborne LiDAR data creates better opportunity for an individual tree measurement and provides valuable results for more precise forest inventory. This paper presents tree filtering approach that able to separate dominant tree and undergrowth vegetation. The results can be used for

  5. Density functional calculations for a high energy density compound of formula C6H 6-n (NO 2) n.

    Science.gov (United States)

    Chi, Wei-Jie; Li, Lu-Lin; Li, Bu-Tong; Wu, Hai-Shun

    2012-08-01

    A series of polynitroprismanes, C(6)H(6-n )(NO(2))(n) (n = 1-6) intended for use as high energy density compounds (HEDCs) were designed computationally. Their electronic structures, heats of formation, interactions between nitro groups, specific enthalpies of combustion, bond dissociation energies, and explosive performances (detonation velocities and detonation pressures) were calculated using density functional theory (DFT) with the 6-311 G** basis set. The results showed that all of the polynitroprismanes had high positive heats of formation that increased with the number of substitutions for the prismane derivatives, while the specific enthalpy of combustion decreased as the number of nitro groups increased. In addition, the range of enthalpy of combustion reducing is getting smaller. Interactions between ortho (vicinal) groups deviate from the group additivity rule and decrease as the number of nitro groups increases. In terms of thermodynamic stability, all of the polynitroprismanes had higher bond dissociation energies (BDEs) than RDX and HMX. Detonation velocities and detonation pressures were estimated using modified Kamlet-Jacobs equations based on the heat of detonation (Q) and the theoretical density of the molecule (ρ). It was found that ρ, D, and P are strongly linearly related to the number of nitro groups. Taking both their energetic properties and thermal stabilities into account, pentanitroprismane and hexanitroprismane are potential candidate HEDCs.

  6. Fiber-Optic Temperature and Pressure Sensors Applied to Radiofrequency Thermal Ablation in Liver Phantom: Methodology and Experimental Measurements

    Directory of Open Access Journals (Sweden)

    Daniele Tosi

    2015-01-01

    Full Text Available Radiofrequency thermal ablation (RFA is a procedure aimed at interventional cancer care and is applied to the treatment of small- and midsize tumors in lung, kidney, liver, and other tissues. RFA generates a selective high-temperature field in the tissue; temperature values and their persistency are directly related to the mortality rate of tumor cells. Temperature measurement in up to 3–5 points, using electrical thermocouples, belongs to the present clinical practice of RFA and is the foundation of a physical model of the ablation process. Fiber-optic sensors allow extending the detection of biophysical parameters to a vast plurality of sensing points, using miniature and noninvasive technologies that do not alter the RFA pattern. This work addresses the methodology for optical measurement of temperature distribution and pressure using four different fiber-optic technologies: fiber Bragg gratings (FBGs, linearly chirped FBGs (LCFBGs, Rayleigh scattering-based distributed temperature system (DTS, and extrinsic Fabry-Perot interferometry (EFPI. For each instrument, methodology for ex vivo sensing, as well as experimental results, is reported, leading to the application of fiber-optic technologies in vivo. The possibility of using a fiber-optic sensor network, in conjunction with a suitable ablation device, can enable smart ablation procedure whereas ablation parameters are dynamically changed.

  7. High Energy Density Solid State Li-ion Battery with Enhanced Safety Project

    Data.gov (United States)

    National Aeronautics and Space Administration — We propose to develop an all solid state Li-ion battery which is capable of delivering high energy density, combined with high safety over a wide operating...

  8. Nanomaterials Enabled High Energy and Power Density Li-ion Batteries Project

    Data.gov (United States)

    National Aeronautics and Space Administration — There is a need for high energy (~ 200 Wh/kg) and high power (> 500 W/kg) density rechargeable Li-ion batteries that are safe and reliable for several space and...

  9. Cultivar and Tree Density As Key Factors in the Long-Term Performance of Super High-Density Olive Orchards

    Science.gov (United States)

    Díez, Concepción M.; Moral, Juan; Cabello, Diego; Morello, Pablo; Rallo, Luis; Barranco, Diego

    2016-01-01

    Super high-density (SHD) olive orchards are rapidly expanding since the first plantation was set up in Spain in the 1990s. Because there are no long-term studies characterizing these systems, it is unknown if densities above a certain threshold could trigger competition among fully-grown trees, compromising their development. Over 14 years we have evaluated the performance of the major olive cultivars currently planted in SHD systems (“Arbequina,” Arbequina IRTA-i·18, “Arbosana,” “Fs-17,” and “Koroneiki”) and nine SHD designs ranging from 780 to 2254 trees ha−1 for the cultivar “Arbequina.” Remarkably, the accumulated fruit and oil production of the five cultivars increased linearly over time. Our data indicated the favorable long-term performance of the evaluated cultivars with an average annual oil production of 2.3 t ha−1. Only “Fs-17” did not perform well to the SHD system in our conditions and it yielded about half (1.2 t ha−1) of the other cultivars. In the density trial for “Arbequina,” both fruit and oil accumulated production increased over time as a function of tree density. Thus, the accumulated oil yield ranged from 16.1 t ha−1 for the lowest density (780 trees ha−1) to 29.9 t ha−1 for the highest (2254 trees ha−1). In addition, we note that the accumulated production per surface unit showed a better correlation with the hedgerow length than the tree density. Thus, the current planting designs of SHD olive orchards can be further improved taking this parameter into account. Despite observations that some irregular patterns of crop distribution have arisen, our olive hedgerows are still fully productive after 14 years of planting. This result contradicts previous experiences that showed declines in production 7 or 8 years after planting due to high vigor, shading, and limited ventilation. PMID:27602035

  10. ADX: a high field, high power density, advanced divertor and RF tokamak

    Science.gov (United States)

    LaBombard, B.; Marmar, E.; Irby, J.; Terry, J. L.; Vieira, R.; Wallace, G.; Whyte, D. G.; Wolfe, S.; Wukitch, S.; Baek, S.; Beck, W.; Bonoli, P.; Brunner, D.; Doody, J.; Ellis, R.; Ernst, D.; Fiore, C.; Freidberg, J. P.; Golfinopoulos, T.; Granetz, R.; Greenwald, M.; Hartwig, Z. S.; Hubbard, A.; Hughes, J. W.; Hutchinson, I. H.; Kessel, C.; Kotschenreuther, M.; Leccacorvi, R.; Lin, Y.; Lipschultz, B.; Mahajan, S.; Minervini, J.; Mumgaard, R.; Nygren, R.; Parker, R.; Poli, F.; Porkolab, M.; Reinke, M. L.; Rice, J.; Rognlien, T.; Rowan, W.; Shiraiwa, S.; Terry, D.; Theiler, C.; Titus, P.; Umansky, M.; Valanju, P.; Walk, J.; White, A.; Wilson, J. R.; Wright, G.; Zweben, S. J.

    2015-05-01

    The MIT Plasma Science and Fusion Center and collaborators are proposing a high-performance Advanced Divertor and RF tokamak eXperiment (ADX)—a tokamak specifically designed to address critical gaps in the world fusion research programme on the pathway to next-step devices: fusion nuclear science facility (FNSF), fusion pilot plant (FPP) and/or demonstration power plant (DEMO). This high-field (⩾6.5 T, 1.5 MA), high power density facility (P/S ˜ 1.5 MW m-2) will test innovative divertor ideas, including an ‘X-point target divertor’ concept, at the required performance parameters—reactor-level boundary plasma pressures, magnetic field strengths and parallel heat flux densities entering into the divertor region—while simultaneously producing high-performance core plasma conditions that are prototypical of a reactor: equilibrated and strongly coupled electrons and ions, regimes with low or no torque, and no fuelling from external heating and current drive systems. Equally important, the experimental platform will test innovative concepts for lower hybrid current drive and ion cyclotron range of frequency actuators with the unprecedented ability to deploy launch structures both on the low-magnetic-field side and the high-magnetic-field side—the latter being a location where energetic plasma-material interactions can be controlled and favourable RF wave physics leads to efficient current drive, current profile control, heating and flow drive. This triple combination—advanced divertors, advanced RF actuators, reactor-prototypical core plasma conditions—will enable ADX to explore enhanced core confinement physics, such as made possible by reversed central shear, using only the types of external drive systems that are considered viable for a fusion power plant. Such an integrated demonstration of high-performance core-divertor operation with steady-state sustainment would pave the way towards an attractive pilot plant, as envisioned in the ARC concept

  11. High population density enhances recruitment and survival of a harvested coral reef fish.

    Science.gov (United States)

    Wormald, Clare L; Steele, Mark A; Forrester, Graham E

    2013-03-01

    A negative relationship between population growth and population density (direct density dependence) is necessary for population regulation and is assumed in most models of harvested populations. Experimental tests for density dependence are lacking for large-bodied, harvested fish because of the difficulty of manipulating population density over large areas. We studied a harvested coral reef fish, Lutjanus apodus (schoolmaster snapper), using eight large, isolated natural reefs (0.4-1.6 ha) in the Bahamas as replicates. An initial observational test for density dependence was followed by a manipulation of population density. The manipulation weakened an association between density and shelter-providing habitat features and revealed a positive effect of population density on recruitment and survival (inverse density dependence), but no effect of density on somatic growth. The snappers on an individual reef were organized into a few shoals, and we hypothesize that large shoals on high-density reefs were less vulnerable to large piscivores (groupers and barracudas) than the small shoals on low-density reefs. Reductions in predation risk for individuals in large social groups are well documented, but because snapper shoals occupied reefs the size of small marine reserves, these ecological interactions may influence the outcome of management actions.

  12. Stability of serum high-density lipoprotein-microRNAs for preanalytical conditions.

    Science.gov (United States)

    Ishikawa, Hiroaki; Yamada, Hiroya; Taromaru, Nao; Kondo, Kanako; Nagura, Ayuri; Yamazaki, Mirai; Ando, Yoshitaka; Munetsuna, Eiji; Suzuki, Koji; Ohashi, Koji; Teradaira, Ryoji

    2017-01-01

    Background Recently, several studies have shown that microRNAs are present in high-density lipoprotein, and high-density lipoprotein-microRNA may be a promising disease biomarker. We investigated the stability of high-density lipoprotein-microRNAs in different storage conditions as this is an important issue for its application to the field of clinical research. Methods microRNAs were extracted from the high-density lipoprotein fraction that was purified from the serum. miR-135 a and miR-223, which are known to be present in high-density lipoprotein, were quantified by quantitative real-time PCR. The influence of preanalytical parameters on the analysis of high-density lipoprotein-miRNAs was examined by the effect of RNase, storage conditions, and freezing and thawing. Results The concentrations of microRNA in high-density lipoprotein were not altered by RNase A treatment (0-100 U/mL). No significant change in these microRNAs was observed after storing serum at room temperature or 4℃ for 0-24 h, and there was a similar result in the cryopreservation for up to two weeks. Also, high-density lipoprotein-microRNAs were stable for, at least, up to five freeze-thaw cycles. Conclusions These results demonstrated that high-density lipoprotein-microRNAs are relatively resistant to various storage conditions. This study provides new and important information on the stability of high-density lipoprotein-microRNAs.

  13. Effect of fiberoptic bronchoscope compared with direct laryngoscope on hemodynamic responses to orotracheal intubation

    Institute of Scientific and Technical Information of China (English)

    ZHANG Guo-hua; XUE Fu-shan; LI Ping; SUN Hai-yan; LIU Kun-peng; XU Ya-chao; LIU Yi; SUN Hai-tao

    2007-01-01

    @@ Fiberoptic bronchoscope (FOB) is an important instrument for respiratory, disorder examination and difficult airway management.1 The fiberoptic intubation can avoid the mechanical stimulus to oropharyngolaryngeal structures thereby it is likely to attenuate hemodynamic responses during orotracheal intubation.

  14. Evidence of the existence of the high-density and low-density phases in deeply-cooled confined heavy water under high pressures

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Zhe; Chen, Sow-Hsin, E-mail: sowhsin@mit.edu [Department of Nuclear Science and Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 (United States); Liu, Kao-Hsiang [Department of Nuclear Science and Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 (United States); Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei 10617, Taiwan (China); Harriger, Leland; Leão, Juscelino B. [National Institute of Standards and Technology Center for Neutron Research, National Institute of Standards and Technology, Gaithersburg, Maryland 20899 (United States)

    2014-07-07

    The average density of D{sub 2}O confined in a nanoporous silica matrix (MCM-41-S) is studied with neutron scattering. We find that below ∼210 K, the pressure-temperature plane of the system can be divided into two regions. The average density of the confined D{sub 2}O in the higher-pressure region is about 16% larger than that in the lower-pressure region. These two regions could represent the so-called “low-density liquid” and “high-density liquid” phases. The dividing line of these two regions, which could represent the associated 1st order liquid-liquid transition line, is also determined.

  15. Portable fiber-optic taper coupled optical microscopy platform

    Science.gov (United States)

    Wang, Weiming; Yu, Yan; Huang, Hui; Ou, Jinping

    2017-04-01

    The optical fiber taper coupled with CMOS has advantages of high sensitivity, compact structure and low distortion in the imaging platform. So it is widely used in low light, high speed and X-ray imaging systems. In the meanwhile, the peculiarity of the coupled structure can meet the needs of the demand in microscopy imaging. Toward this end, we developed a microscopic imaging platform based on the coupling of cellphone camera module and fiber optic taper for the measurement of the human blood samples and ascaris lumbricoides. The platform, weighing 70 grams, is based on the existing camera module of the smartphone and a fiber-optic array which providing a magnification factor of 6x.The top facet of the taper, on which samples are placed, serves as an irregular sampling grid for contact imaging. The magnified images of the sample, located on the bottom facet of the fiber, are then projected onto the CMOS sensor. This paper introduces the portable medical imaging system based on the optical fiber coupling with CMOS, and theoretically analyzes the feasibility of the system. The image data and process results either can be stored on the memory or transmitted to the remote medical institutions for the telemedicine. We validate the performance of this cell-phone based microscopy platform using human blood samples and test target, achieving comparable results to a standard bench-top microscope.

  16. ICRF array module development and optimization for high power density

    Energy Technology Data Exchange (ETDEWEB)

    Ryan, P.M.; Swain, D.W.

    1997-02-01

    This report describes the analysis and optimization of the proposed International Thermonuclear Experimental Reactor (ITER) Antenna Array for the ion cyclotron range of frequencies (ICRF). The objectives of this effort were to: (1) minimize the applied radiofrequency rf voltages occurring in vacuum by proper layout and shape of components, limit the component`s surface/volumes where the rf voltage is high; (2) study the effects of magnetic insulation, as applied to the current design; (3) provide electrical characteristics of the antenna for the development and analysis of tuning, arc detection/suppression, and systems for discriminating between arcs and edge-localized modes (ELMs); (4) maintain close interface with mechanical design.

  17. High-density QCD with CMS at the LHC

    CERN Document Server

    d'Enterria, David

    2008-01-01

    The capabilities of the CMS experiment to explore the rich heavy-ion physics programme offered by the CERN Large Hadron Collider (LHC) are summarised. Various representative measurements in Pb-Pb collisions at $\\sqrt(s)$ = 5.5 TeV are covered. These include "bulk" observables -- charged hadron multiplicity, low-$p_{T}$ inclusive hadron spectra and elliptic flow -- which provide information on the collective properties of the system; as well as perturbative processes -- high-$p_{T}$ hadrons, jets, $\\gamma$-jet and quarkonia production -- which yield "tomographic" information of the densest phases of the reaction.

  18. Synthesis of Novel High Energy Density Materials Using Nitrocarbenes

    Science.gov (United States)

    1992-02-21

    synthesis is our finding that the combination of titanium tetrachloride/methylene bromide/zinc smoothly converts the caged diketone to the bismethylene...AD-A248 465 AO PAGE ft 07ŕ Februa re 21 , 992uq" Final~o Repotm 8//9 -12319 4. TITLE AND SUBTITLE S. FUNOING NUMBERS Synthesis of Novel High Energy...theory to predict the structures and energies of potential energetic molecules and to guide the synthesis of the more promising candidate molecules, 2

  19. Drift waves in a high-density cylindrical helicon discharge

    DEFF Research Database (Denmark)

    Schröder, C.; Grulke, O.; Klinger, T.

    2005-01-01

    of the background plasma parameters. All experimentally observed features of the instability are found to be consistent with drift waves. A linear nonlocal numerical model for drift modes, based on the two-fluid description of a plasma, is used for comparison between the experimental observations and theory....... Comparing numerical and experimental frequencies, it is found that the experimentally observed frequencies are consistent with drift waves. The numerical results show that the high electron collision frequencies provide the strongest destabilization mechanism in the helicon plasma. (c) 2005 American...

  20. On The Use Of High-Density Rock In Rubble Mound Breakwaters

    DEFF Research Database (Denmark)

    Helgason, Einar; Burcharth, H. F.

    2005-01-01

    Natural rock with high density is widely used in the Scandinavian countries. However, the use of natural rock with density higher than 2:9t=m3 is ordinarily associated with some kind of problem solving, e.g. where normal density stones have to be replaced with heavier stones without increasing th...... on stability from the increased density is overestimated by conventional armour stability formulae in case of steep slopes. The infuence of the density depends on the slope angle and the type of armour units....... the construction volume or layer thickness. Most common design formulae do not give a clear conclusion on the in°uence of the rock density on the stability. The present paper presents results of small and large scale model tests in which is used rock with different densities. It is shown that the positive effect...

  1. Fiber-optically sensorized composite wing

    Science.gov (United States)

    Costa, Joannes M.; Black, Richard J.; Moslehi, Behzad; Oblea, Levy; Patel, Rona; Sotoudeh, Vahid; Abouzeida, Essam; Quinones, Vladimir; Gowayed, Yasser; Soobramaney, Paul; Flowers, George

    2014-04-01

    Electromagnetic interference (EMI) immune and light-weight, fiber-optic sensor based Structural Health Monitoring (SHM) will find increasing application in aerospace structures ranging from aircraft wings to jet engine vanes. Intelligent Fiber Optic Systems Corporation (IFOS) has been developing multi-functional fiber Bragg grating (FBG) sensor systems including parallel processing FBG interrogators combined with advanced signal processing for SHM, structural state sensing and load monitoring applications. This paper reports work with Auburn University on embedding and testing FBG sensor arrays in a quarter scale model of a T38 composite wing. The wing was designed and manufactured using fabric reinforced polymer matrix composites. FBG sensors were embedded under the top layer of the composite. Their positions were chosen based on strain maps determined by finite element analysis. Static and dynamic testing confirmed expected response from the FBGs. The demonstrated technology has the potential to be further developed into an autonomous onboard system to perform load monitoring, SHM and Non-Destructive Evaluation (NDE) of composite aerospace structures (wings and rotorcraft blades). This platform technology could also be applied to flight testing of morphing and aero-elastic control surfaces.

  2. Advanced Polymer Electrolytes for High-energy-density Power Sources

    Institute of Scientific and Technical Information of China (English)

    D. Golodnitsky; E. Livshits; R. Kovarsky; E. Peled

    2005-01-01

    @@ 1Introduction The preparation of highly controlled thin films of lithium ion conducting organic materials is becoming a challenging but rewarding goal in view of obtaining high-performance technological devices like solid-state polymer batteries and capacitors. The classical polymer electrolyte consists of organic macromolecules (usually polyether polymer) that are doped with inorganic (typically lithium) salts. Poly(ethylene oxide) (PEO) is the most commonly employed polymer in PEs because of the peculiar array in the (-CH2-CH2-O-)n chain providing the ability to solvate low-lattice-energy lithium salts. For three decades the major research attention was focused on amorphous polymer electrolytes in the belief that ionic conductivity occurs in a manner somewhat analogous to gas diffusion through polymer membranes. Segmental motion of the polymer chains continuously creates free volume, into which the ions migrate, and this process allows ions to progress across the electrolyte. Such a view was established by a number of experiments, and denied the possibility of ionic conductivity in crystalline polymer phases. This concept has been recently overturned by our group, demonstrating that conductivity comes about as a result of permanent conducting pathways for the movement of ions.

  3. Expansion of Endothelial Progenitor Cells in High Density Dot Culture of Rat Bone Marrow Cells

    Science.gov (United States)

    Wang, Ling; Kretlow, James D.; Zhou, Guangdong; Cao, Yilin; Liu, Wei; Zhang, Wen Jie

    2014-01-01

    In vitro expansion of endothelial progenitor cells (EPCs) remains a challenge in stem cell research and its application. We hypothesize that high density culture is able to expand EPCs from bone marrow by mimicking cell-cell interactions of the bone marrow niche. To test the hypothesis, rat bone marrow cells were either cultured in high density (2×105 cells/cm2) by seeding total 9×105 cells into six high density dots or cultured in regular density (1.6×104 cells/cm2) with the same total number of cells. Flow cytometric analyses of the cells cultured for 15 days showed that high density cells exhibited smaller cell size and higher levels of marker expression related to EPCs when compared to regular density cultured cells. Functionally, these cells exhibited strong angiogenic potentials with better tubal formation in vitro and potent rescue of mouse ischemic limbs in vivo with their integration into neo-capillary structure. Global gene chip and ELISA analyses revealed up-regulated gene expression of adhesion molecules and enhanced protein release of pro-angiogenic growth factors in high density cultured cells. In summary, high density cell culture promotes expansion of bone marrow contained EPCs that are able to enhance tissue angiogenesis via paracrine growth factors and direct differentiation into endothelial cells. PMID:25254487

  4. Learning curves and effect of high-fidelity simulation-based training with virtual reality simulator in flexible fiberoptic intubation%高仿真模拟训练在纤维支气管镜插管教学中的应用及学习曲线研究

    Institute of Scientific and Technical Information of China (English)

    姜柏林; 赵莹; 鞠辉; 姚兰; 冯艺

    2016-01-01

    目的:拟合高仿真模拟教学中纤维支气管镜插管的学习曲线,验证高仿真模拟教学的教学效果。方法选择在北京大学人民医院接受住院医师第一阶段培训,且无纤支镜插管经验的45名麻醉学住院医师作为本研究对象,将其随机分为两组:实验组25人,对照组20人。实验组和对照组医师均观看教学短片,观摩纤支镜插管操作。实验组医师采用 Simbionix GI-Bronch Mentor虚拟真实模拟平台完成25次纤支镜置入气道的模拟操作,对照组医师不进行模拟操作。两组医师均在模拟人头上进行5次考核。记录实验组医师每次模拟培训的操作时间,拟合学习曲线。对比两组医师操作时间和纤支镜操作能力评分。对比实验组医师培训前后的信心评分。结果学习曲线拟合的专业级操作时间为9.3(8.7,10.0)秒,19(15,26)次操作后学习曲线进入平台期。实验组医师的操作时间及操作能力评分均优于对照组医师,F =24.993、P <0.001,F=107.357、P <0.001,差异具有统计学意义。培训后,实验组医师信心评分高于培训前,t =10.708,P <0.001,差异具有统计学意义。结论高仿真模拟教学可以使无纤支镜使用经验的初学者快速通过学习曲线的陡峭段,达到专业级操作时间。19次训练和操作时间趋近9.0秒,可以结合使用,作为达到学习目标的终点设置。%Objective To evaluate the learning curves of residents performing flexible fiberoptic intubation in high-fidelity simulation environment,and assess the effects of training.Methods A total of 45 anesthesia residents in their first stage of training in anesthesiology with no experience in flexible fiber-optic intubation at Peking University People’s Hospital were enrolled in the study,and were divided into two groups randomly:the simulator group (25 residents),and the control group (20

  5. Comparison of combined application of fiberoptic ductoscopy and high - frequency ultrasonography with traditional orientation method in the surgery of intraductal papilloma%乳管内窥镜联合高频超声定位法与传统定位法在乳头状瘤手术中的应用比较

    Institute of Scientific and Technical Information of China (English)

    刘巧刿; 周成礼; 屈淑娥; 孙德胜; 于志强; 韦伟

    2011-01-01

    目的 研究乳管内窥镜与高频超声在乳头状瘤术前联合应用的临床意义.方法 将有母乳喂养需求的73例乳腺导管内乳头状瘤患者随机分为两组,对照组33例采用传统美蓝定位法或乳管扩张器定位法手术,研究组40例采用乳管镜联合高频超声定位法进行肿瘤手术,比较乳管镜联合高频超声定位法与传统定位法的误诊率,观察和比较患者产后乳汁分泌情况.结果 两组患者比较,研究组误诊率(7.50%)明显低于对照组(24.24%),术后研究组10例、对照组8例正常哺乳,乳汁分泌正常率分别为90.00%和37.50%.结论 乳管内窥镜联合高频超声定位法比传统的定位法在乳腺中小导管内乳头状瘤的手术治疗中具有更优势的效果,不仅能够减少手术损伤、获得准确定位,还能最大程度地满足哺乳期妇女正常产奶的愿望,并保持乳房对称与完好曲线,适合于临床推广.%Objective To investigate the clinical significance of fiberoptic ductoscopy combined with high - frequency ultrasound localization in intraductal papilloma surgery.Methods Seventy - three intraductal papilloma patients who demanded breasffeeding were randomly divided into two groups for tumor surgery: 33 patients ( control group ) treated by conventional methylene blue localization method or lacteal tube expander localization method, 40 patients ( study group ) treated by fiberoptic ductoscopy combined with high - frequency ultrasonography localization method.Misdiagnosis rate and postpartum milk production were compared between two groups.Results The misdiagnosis rate in study group ( 7.50% ) was significantly lower than control group ( 24.24% ), and the rate of normal milk secretion in study group ( 90.00% ) was significantly higher than control group ( 37.50% ) ( P < 0.05 ).Conclusion The fiberoptic ductoscopy combined with high - frequency ultrasound localization method has many advantages including accurate

  6. A High Power Density DC-DC Converter for Distributed PV Architectures

    Energy Technology Data Exchange (ETDEWEB)

    Agamy, Mohammed S; Chi, Song; Elasser, Ahmed; Harfman-Todorovic, Maja; Jiang, Yan; Mueller, Frank; Tao, Fengfeng

    2012-06-01

    In order to maximize solar energy harvesting capabilities, power converters have to be designed for high efficiency and good MPPT and voltage/current performance. When many converters are used in distributed systems, power density also becomes an important factor as it allows for simpler system integration. In this paper a high power density string dc-dc converter suitable for distributed medium to large scale PV installation is presented. A simple partial power processing topology, implemented with all silicon carbide devices provides high efficiency as well as high power density. A 3.5kW, 100kHz converter is designed and tested to verify the proposed methods.

  7. A carbon nanotube field emission cathode with high current density and long-term stability

    Science.gov (United States)

    Calderón-Colón, Xiomara; Geng, Huaizhi; Gao, Bo; An, Lei; Cao, Guohua; Zhou, Otto

    2009-08-01

    Carbon nanotube (CNT) field emitters are now being evaluated for a wide range of vacuum electronic applications. However, problems including short lifetime at high current density, instability under high voltage, poor emission uniformity, and pixel-to-pixel inconsistency are still major obstacles for device applications. We developed an electrophoretic process to fabricate composite CNT films with controlled nanotube orientation and surface density, and enhanced adhesion. The cathodes have significantly enhanced macroscopic field emission current density and long-term stability under high operating voltages. The application of this CNT electron source for high-resolution x-ray imaging is demonstrated.

  8. High density THz frequency comb produced by coherent synchrotron radiation

    CERN Document Server

    Tammaro, S; Roy, P; Lampin, J -F; Ducournau, G; Cuisset, A; Hindle, F; Mouret, G

    2014-01-01

    Frequency combs (FC) have radically changed the landscape of frequency metrology and high-resolution spectroscopy investigations extending tremendously the achievable resolution while increasing signal to noise ratio. Initially developed in the visible and near-IR spectral regions, the use of FC has been expanded to mid-IR, extreme ultra-violet and X-ray. Significant effort is presently dedicated to the generation of FC at THz frequencies. One solution based on converting a stabilized optical frequency comb using a photoconductive terahertz emitter, remains hampered by the low available THz power. Another approach is based on active mode locked THz quantum-cascade-lasers providing intense FC over a relatively limited spectral extension. Alternatively, here we show that dense powerful THz FC is generated over one decade of frequency by coherent synchrotron radiation (CSR). In this mode, the entire ring behaves in a similar fashion to a THz resonator wherein electron bunches emit powerful THz pulses quasi-synch...

  9. Non-Boussinesq turbulent buoyant jet of a low-density gas leaks into high-density ambient

    KAUST Repository

    El-Amin, Mohamed

    2010-12-01

    In this article, we study the problem of low-density gas jet injected into high-density ambient numerically which is important in applications such as fuel injection and leaks. It is assumed that the local rate of entrainment is consisted of two components; one is the component of entrainment due to jet momentum while the other is the component of entrainment due to buoyancy. The integral models of the mass, momentum and concentration fluxes are obtained and transformed to a set of ordinary differential equations using some similarity transformations. The resulting system is solved to determine the centerline quantities which are used to get the mean axial velocity, mean concentration and mean density of the jet. Therefore, the centerline and mean quantities are used together with the governing equation to determine some important turbulent quantities such as, cross-stream velocity, Reynolds stress, velocity- concentration correlation, turbulent eddy viscosity and turbulent eddy diffusivity. Throughout this paper the developed model is verified by comparing the present results with experimental results and jet/plume theory from the literature. © 2010 Elsevier Inc. All rights reserved.

  10. Compatibility of advanced tokamak plasma with high density and high radiation loss operation in JT-60U

    Science.gov (United States)

    Takenaga, H.; Asakura, N.; Kubo, H.; Higashijima, S.; Konoshima, S.; Nakano, T.; Oyama, N.; Porter, G. D.; Rognlien, T. D.; Rensink, M. E.; Ide, S.; Fujita, T.; Takizuka, T.; Kamada, Y.; Miura, Y.; JT-60 Team

    2005-12-01

    Compatibility of advanced tokamak plasmas with high density and high radiation loss has been investigated in both reversed shear (RS) plasmas and high βp H-mode plasmas with a weak positive shear on JT-60U. In the RS plasmas, the operating regime is extended to high density above the Greenwald density (nGW) with high confinement (HHy2 > 1) and high radiation loss fraction (frad > 0.9) by tailoring the internal transport barriers (ITBs). With a small plasma-wall gap, the radiation loss in the main plasma (inside the magnetic separatrix) reaches 80% of the heating power due to metal impurity accumulation. However, high confinement of HHy2 = 1.2 is sustained even with such a large radiation loss in the main plasma. By neon seeding, the divertor radiation loss is enhanced from 20% to 40% of the total radiation loss. In the high βp H-mode plasmas, high confinement (HHy2 = 0.96) is maintained at high density ( \\bar{n}_{\\rme}/n_GW=0.92 ) with high radiation loss fraction (frad ~ 1) by utilizing high-field-side pellets and argon (Ar) injection. The high \\bar{n}_{\\rme}/n_GW is attributed to the formation of strong density ITB. Strong core-edge parameter linkage for confinement improvement is observed, where the pedestal pressure and the core plasma confinement increase together. The measured radiation profile including contributions from all impurities in the main plasma is peaked, and the central radiation is ascribed to the contribution from Ar accumulated inside the ITB. Impurity transport analyses indicate that the Ar density profile, twice as peaked as the electron density profile, which is the same level as that observed in the high βp H-mode plasma, can yield an acceptable radiation profile even with a peaked density profile in a fusion reactor.

  11. Ion density and dielectric breakdown in the afterglow of a high-current arc discharge

    Energy Technology Data Exchange (ETDEWEB)

    Rutgers, W.R.; Verhagen, F.C.M.; De Zeeuw, W.A.

    1984-01-01

    The ion density in the afterglow of a high-current atmospheric arc-discharge and electrical breakdown have been investigated in atomic (argon), molecular (nitrogen) and electronegative (carbon dioxide) media. From the decay with time of the ion density, effective recombination coefficients can be calculated. When the ion density is reduced to values below 2 x 10/sup 17/m/sup -3/, the afterglow plasma changes from a resistive into a dielectric medium. (J.C.R.)

  12. A high-density screen for linkage in multiple sclerosis.

    Science.gov (United States)

    Sawcer, Stephen; Ban, Maria; Maranian, Mel; Yeo, Tai Wai; Compston, Alastair; Kirby, Andrew; Daly, Mark J; De Jager, Philip L; Walsh, Emily; Lander, Eric S; Rioux, John D; Hafler, David A; Ivinson, Adrian; Rimmler, Jacqueline; Gregory, Simon G; Schmidt, Silke; Pericak-Vance, Margaret A; Akesson, Eva; Hillert, Jan; Datta, Pameli; Oturai, Annette; Ryder, Lars P; Harbo, Hanne F; Spurkland, Anne; Myhr, Kjell-Morten; Laaksonen, Mikko; Booth, David; Heard, Robert; Stewart, Graeme; Lincoln, Robin; Barcellos, Lisa F; Hauser, Stephen L; Oksenberg, Jorge R; Kenealy, Shannon J; Haines, Jonathan L

    2005-09-01

    To provide a definitive linkage map for multiple sclerosis, we have genotyped the Illumina BeadArray linkage mapping panel (version 4) in a data set of 730 multiplex families of Northern European descent. After the application of stringent quality thresholds, data from 4,506 markers in 2,692 individuals were included in the analysis. Multipoint nonparametric linkage analysis revealed highly significant linkage in the major histocompatibility complex (MHC) on chromosome 6p21 (maximum LOD score [MLS] 11.66) and suggestive linkage on chromosomes 17q23 (MLS 2.45) and 5q33 (MLS 2.18). This set of markers achieved a mean information extraction of 79.3% across the genome, with a Mendelian inconsistency rate of only 0.002%. Stratification based on carriage of the multiple sclerosis-associated DRB1*1501 allele failed to identify any other region of linkage with genomewide significance. However, ordered-subset analysis suggested that there may be an additional locus on chromosome 19p13 that acts independent of the main MHC locus. These data illustrate the substantial increase in power that can be achieved with use of the latest tools emerging from the Human Genome Project and indicate that future attempts to systematically identify susceptibility genes for multiple sclerosis will have to involve large sample sizes and an association-based methodology.

  13. High herbivore density associated with vegetation diversity in interglacial ecosystems.

    Science.gov (United States)

    Sandom, Christopher J; Ejrnæs, Rasmus; Hansen, Morten D D; Svenning, Jens-Christian

    2014-03-18

    The impact of large herbivores on ecosystems before modern human activities is an open question in ecology and conservation. For Europe, the controversial wood-pasture hypothesis posits that grazing by wild large herbivores supported a dynamic mosaic of vegetation structures at the landscape scale under temperate conditions before agriculture. The contrasting position suggests that European temperate vegetation was primarily closed forest with relatively small open areas, at most impacted locally by large herbivores. Given the role of modern humans in the world-wide decimations of megafauna during the late Quaternary, to resolve this debate it is necessary to understand herbivore-vegetation interactions before these losses. Here, a synthetic analysis of beetle fossils from Great Britain shows that beetles associated with herbivore dung were better represented during the Last Interglacial (132,000-110,000 y B.P., before modern human arrival) than in the early Holocene (10,000-5,000 y B.P.). Furthermore, beetle assemblages indicate closed and partially closed forest in the early Holocene but a greater mixture of semiopen vegetation and forest in the Last Interglacial. Hence, abundant and diverse large herbivores appear to have been associated with high structural diversity of vegetation before the megafauna extinctions at the end of the Pleistocene. After these losses and in the presence of modern humans, large herbivores generally were less abundant, and closed woodland was more prevalent in the early Holocene. Our findings point to the importance of the formerly rich fauna of large herbivores in sustaining structurally diverse vegetation in the temperate forest biome and provide support for recent moves toward rewilding-based conservation management.

  14. Anatomical traits related to stress in high density populations of Typha angustifolia L. (Typhaceae).

    Science.gov (United States)

    Corrêa, F F; Pereira, M P; Madail, R H; Santos, B R; Barbosa, S; Castro, E M; Pereira, F J

    2017-03-01

    Some macrophytes species show a high growth potential, colonizing large areas on aquatic environments. Cattail (Typha angustifolia L.) uncontrolled growth causes several problems to human activities and local biodiversity, but this also may lead to competition and further problems for this species itself. Thus, the objective of this study was to investigate anatomical modifications on T. angustifolia plants from different population densities, once it can help to understand its biology. Roots and leaves were collected from natural populations growing under high and low densities. These plant materials were fixed and submitted to usual plant microtechnique procedures. Slides were observed and photographed under light microscopy and images were analyzed in the UTHSCSA-Imagetool software. The experimental design was completely randomized with two treatments and ten replicates, data were submitted to one-way ANOVA and Scott-Knott test at p<0.05. Leaves from low density populations showed higher stomatal density and index. These modifications on stomatal characteristics were more evident on the leaf abaxial surface. Plants from low density populations showed thicker mesophyll and higher proportion of aerenchymal area. Roots from low density populations showed a higher proportion of the vascular cylinder. Whereas, plants from higher density populations showed greater thickness of the endodermis, exodermis, phloem and root cortex. Higher density populations showed a higher proportion of aerenchymal gaps in the root cortex. Therefore, cattail plants from populations growing under high density population show anatomical traits typical of plants under stress, which promotes the development of less functional anatomical modifications to aquatic environments.

  15. Effects of Electron Screening on Electron Capture Rates in High Density Presupernova Core

    Institute of Scientific and Technical Information of China (English)

    蒋广飞; 彭秋和; 邹志刚

    2003-01-01

    Considering that the electron capture rate can be greatly reduced by the electron screening effect in the regime of high temperature and high density, we calculate the effect of electron screening on the electron capture rate for two important elements 56Ni and 55Co in the high density condition of a pre-supernova star. The effect of electron screening is so effective that the electron capture rate may be reduced to about 20%.

  16. Development of novel cathodes for high energy density lithium batteries

    Science.gov (United States)

    Bhargav, Amruth

    Lithium based batteries have become ubiquitous with our everyday life. They have propelled a generation of smart personal electronics and electric transport. Their use is now percolating to various fields as a source of energy to facilitate the operation of devices from nanoscale to mega scale. This need for a portable energy source has led to tremendous scientific interest in this field to develop electrochemical devices like batteries with higher capacities, longer cycle life and increased safety at a low cost. To this end, the research presented in this thesis focuses on two emerging and promising technologies called lithium-oxygen (Li-O2) and lithium-sulfur (Li-S) batteries. These batteries can offer an order of magnitude higher capacities through cheap, environmentally safe and abundant elements namely oxygen and sulfur. The first work introduces the concept of closed system lithium-oxygen batteries wherein the cell contains the discharge product of Li-O2 batteries namely, lithium peroxide (Li2O2) as the starting active material. The reversibility of this system is analyzed along with its rate performance. The possible use of such a cathode in a full cell is explored. Also, this concept is used to verify if all the lithium can be extracted from the cathode in the first charge. In the following work, lithium peroxide is chemically synthesized and deposited in a carbon nanofiber matrix. This forms a free standing cathode that shows high reversibility. It can be cycled up to 20 times and while using capacity control protocol, a cycle life of 50 is obtained. The cause of cell degradation and failure is also analyzed. In the work on full cell lithium-sulfur system, a novel electrolyte is developed that can support reversible lithium insertion and extraction from a graphite anode. A method to deposit solid lithium polysulfide is developed for the cathode. Coupling a lithiated graphite anode with the cathode using the new electrolyte yields a full cell whose

  17. Novel adaptive fiber-optics collimator for coherent beam combination.

    Science.gov (United States)

    Zhi, Dong; Ma, Pengfei; Ma, Yanxing; Wang, Xiaolin; Zhou, Pu; Si, Lei

    2014-12-15

    In this manuscript, we experimentally validate a novel design of adaptive fiber-optics collimator (AFOC), which utilizes two levers to enlarge the movable range of the fiber end cap. The enlargement of the range makes the new AFOC possible to compensate the end-cap/tilt aberration in fiber laser beam combining system. The new AFOC based on flexible hinges and levers was fabricated and the performance of the new AFOC was tested carefully, including its control range, frequency response and control accuracy. Coherent beam combination (CBC) of two 5-W fiber amplifiers array with simultaneously end-cap/tilt control and phase-locking control was implemented successfully with the novel AFOC. Experimental results show that the average normalized power in the bucket (PIB) value increases from 0.311 to 0.934 with active phasing and tilt aberration compensation simultaneously, and with both controls on, the fringe contrast improves to more than 82% from 0% for the case with both control off. This work presents a promising structure for tilt aberration control in high power CBC system.

  18. Fiber-Optic Surface Temperature Sensor Based on Modal Interference

    Directory of Open Access Journals (Sweden)

    Frédéric Musin

    2016-07-01

    Full Text Available Spatially-integrated surface temperature sensing is highly useful when it comes to controlling processes, detecting hazardous conditions or monitoring the health and safety of equipment and people. Fiber-optic sensing based on modal interference has shown great sensitivity to temperature variation, by means of cost-effective image-processing of few-mode interference patterns. New developments in the field of sensor configuration, as described in this paper, include an innovative cooling and heating phase discrimination functionality and more precise measurements, based entirely on the image processing of interference patterns. The proposed technique was applied to the measurement of the integrated surface temperature of a hollow cylinder and compared with a conventional measurement system, consisting of an infrared camera and precision temperature probe. As a result, the optical technique is in line with the reference system. Compared with conventional surface temperature probes, the optical technique has the following advantages: low heat capacity temperature measurement errors, easier spatial deployment, and replacement of multiple angle infrared camera shooting and the continuous monitoring of surfaces that are not visually accessible.

  19. Tri-Axial MRI Compatible Fiber-optic Force Sensor

    Science.gov (United States)

    Tan, U-Xuan; Yang, Bo; Gullapalli, Rao; Desai, Jaydev P.

    2011-01-01

    Magnetic resonance imaging (MRI) has been gaining popularity over standard imaging modalities like ultrasound and CT because of its ability to provide excellent soft-tissue contrast. However, due to the working principle of MRI, a number of conventional force sensors are not compatible. One popular solution is to develop a fiber-optic force sensor. However, the measurements along the principal axes of a number of these force sensors are highly cross-coupled. One of the objectives of this paper is to minimize this coupling effect. In addition, this paper describes the design of elastic frame structures that are obtained systematically using topology optimization techniques for maximizing sensor resolution and sensor bandwidth. Through the topology optimization approach, we ensure that the frames are linked from the input to output. The elastic frame structures are then fabricated using polymers materials, such as ABS and Delrin®, as they are ideal materials for use in MRI environment. However, the hysteresis effect seen in the displacement-load graph of plastic materials is known to affect the accuracy. Hence, this paper also proposes modeling and addressing this hysteretic effect using Prandtl-Ishlinskii play operators. Finally, experiments are conducted to evaluate the sensor’s performance, as well as its compatibility in MRI under continuous imaging. PMID:21666783

  20. Cardiac arrhythmias during fiberoptic bronchoscopy and relation with oxygen saturation

    Directory of Open Access Journals (Sweden)

    Hassan G

    2005-01-01

    Full Text Available To evaluate the occurrence of electrocardiographic abnormalities during fiberoptic bronchoscopy, in relation to specific stages of the procedures, patients′ age, sex, smoking, pre-existing lung disease, premedication and oxygen saturation, a prospective study was conducted on 56 patients aged 35 to 75 (mean 62 years without pre-existing cardiovascular disease. Patients were connected to a 12-lead computerized electrocardiographic recorder and pulse oximeter. Fall of oxygen saturation from mean of 95.12% before the procedure to below 80% was observed in 12 (21.4% patients and below 75% in 5 (8.9% patients, at various stages. Statistically highly significant (p < 0.001 fall of oxygen saturation was observed during the procedures while bronchoscope was introduced into the airways and tracheobronchial tree examined. Major disturbances of cardiac rhythm (i.e. atrial, ventricular or both developed in 23 (41.07% patients. Out of these, sinus tachycardia was noted in 16 (69.5%, ventricular premature complexes in 5 (21.7% and paroxysmal supraventricular tachycardia in 2 (8.6% patients. Arrhythmias were most frequent in association with periods of maximum oxygen desaturation in 18 (78.2% of these 23 patients. Oxygen desaturation persisted for more than half an hour in 38 (67.8% of the 56 patients. However, no correlation was observed between the frequency of arrhythmias during bronchoscopy and patients′ age, sex pre-medication or pre-existing pulmonary disease.

  1. A Fiber-Optic Aircraft Lightning Current Measurement Sensor

    Science.gov (United States)

    Nguyen, Truong X.; Ely, Jay J.; Szatkowski, George N.

    2013-01-01

    A fiber-optic current sensor based on the Faraday Effect is developed for aircraft installations. It can measure total lightning current amplitudes and waveforms, including continuing current. Additional benefits include being small, lightweight, non-conducting, safe from electromagnetic interference, and free of hysteresis and saturation. The Faraday Effect causes light polarization to rotate in presence of magnetic field in the direction of light propagation. Measuring the total induced light polarization change yields the total current enclosed. The system operates at 1310nm laser wavelength and can measure approximately 300 A - 300 kA, a 60 dB range. A reflective polarimetric scheme is used, where the light polarization change is measured after a round-trip propagation through the fiber. A two-detector setup measures the two orthogonal polarizations for noise subtraction and improved dynamic range. The current response curve is non-linear and requires a simple spline-fit correction. Effects of high current were achieved in laboratory using combinations of multiple fiber and wire loops. Good result comparisons against reference sensors were achieved up to 300 kA. Accurate measurements on a simulated aircraft fuselage and an internal structure illustrate capabilities that maybe difficult with traditional sensors. Also tested at a commercial lightning test facility from 20 kA to 200 kA, accuracy within 3-10% was achieved even with non-optimum setups.

  2. High-density lipoprotein cholesterol on a roller coaster: where will the ride end?

    Science.gov (United States)

    Kronenberg, Florian

    2016-04-01

    Bowe et al. report an association between low high-density lipoprotein cholesterol concentrations and various incident chronic kidney disease end points in a cohort of almost 2 million US veterans followed for 9 years. These impressive data should be a starting point for further investigations including genetic epidemiologic investigations as well as post hoc analyses of interventional trials that target high-density lipoprotein cholesterol and, finally, studies that focus on the functionality of high-density lipoprotein particles.

  3. Should we change our lipid management strategies to focus on non-high-density lipoprotein cholesterol?

    NARCIS (Netherlands)

    J.S. Rana; S.M. Boekholdt

    2010-01-01

    Purpose of review Despite aggressive low-density lipoprotein cholesterol lowering, patients continue to be at significant risk of cardiovascular events. Assessment of non-high-density lipoprotein cholesterol (non-HDL-C) provides a measure of cholesterol contained in all atherogenic particles. In the

  4. A high plant density reduces the ability of maize to use soil nitrogen.

    Science.gov (United States)

    Yan, Peng; Pan, Junxiao; Zhang, Wenjie; Shi, Junfang; Chen, Xinping; Cui, Zhenling

    2017-01-01

    Understanding the physiological changes associated with high grain yield and high N use efficiency (NUE) is important when increasing the plant density and N rate to develop optimal agronomic management. We tested the hypothesis that high plant densities resulting in crowding stress reduce the ability of plants to use the N supply post-silking, thus decreasing the grain yield and NUE. In 2013 and 2014, a field experiment, with five N-application rates and three plant densities (6.0, 7.5, and 9.0 plants m-2), was conducted in the North China Plain (NCP). The calculated maximum grain yield and agronomic use efficiency (AEN) at a density of 7.5 plants m-2 were 12.4 Mg ha-1 and 39.3 kg kg-1, respectively, which were significantly higher than the values obtained at densities of 6.0 (11.3 Mg ha-1 and 30.2 kg kg-1) and 9.0 plant m-2 (11.7 Mg ha-1 and 27.8 kg kg-1). A high plant density of 9.0 plants m-2 decreased the post-silking N accumulation, leaf N concentration and net photosynthesis, which reduced the post-silking dry matter production, resulting in a low yield and NUE. Although a relatively low grain yield was observed at a density of 9.0 plants m-2, the optimal N rate increased from 150 to 186 kg N ha-1 at a density of 7.5 plants m-2. These results indicate that high plant densities with crowding stress reduce the ability of plants to use soil N during the post-silking period, and high rate of N fertilizer was needed to increase grain yield. We conclude that selecting the appropriate plant density combined with optimal N management could increase grain yields and the NUE in the NCP.

  5. Growth of high-density horizontally aligned SWNT arrays using Trojan catalysts.

    Science.gov (United States)

    Hu, Yue; Kang, Lixing; Zhao, Qiuchen; Zhong, Hua; Zhang, Shuchen; Yang, Liangwei; Wang, Zequn; Lin, Jingjing; Li, Qingwen; Zhang, Zhiyong; Peng, Lianmao; Liu, Zhongfan; Zhang, Jin

    2015-01-20

    Single-walled carbon nanotube (SWNT)-based electronics have been regarded as one of the most promising candidate technologies to replace or supplement silicon-based electronics in the future. These applications require high-density horizontally aligned SWNT arrays. During the past decade, significant efforts have been directed towards growth of high-density SWNT arrays. However, obtaining SWNT arrays with suitable density and quality still remains a big challenge. Herein, we develop a rational approach to grow SWNT arrays with ultra-high density using Trojan catalysts. The density can be as high as 130 SWNTs μm(-1). Field-effect transistors fabricated with our SWNT arrays exhibit a record drive current density of -467.09 μA μm(-1) and an on-conductance of 233.55 μS μm(-1). Radio frequency transistors fabricated on these samples exhibit high intrinsic fT and fMAX of 6.94 and 14.01 GHz, respectively. These results confirm our high-density SWNT arrays are strong candidates for applications in electronics.

  6. PRODUCTION OF HIGH DENSITY PARTICLEBOARD USING MELAMINE-UREA-FORMALDEHYDE RESIN

    Directory of Open Access Journals (Sweden)

    Setsuo Iwakiri

    2005-12-01

    Full Text Available This research was developed aiming to evaluate the effects of board density and melamine-urea-formaldehyde resin onthe properties of particleboard for semi-structural applications. The boards were manufactured with nominal density of 0.65 g/cm³and 0.90 g/cm³ using urea-formaldehyde resin as control and melamine-urea-formaldehyde. The results showed a better dimensionallystability and mechanical properties of the boards manufactured with higher density and MUF resin content. The fine furnish usedfor external layer of particleboard in the industrial process, could be used for high density homogeneous board to semi-strucuturaluses, such as flooring applications.

  7. Interferometric measurement of injection nozzles using ultra-small fiber-optical probes

    Institute of Scientific and Technical Information of China (English)

    Tilo Pfeifer; Robert Schmitt; Niels K(o)nig; Guilherme Francisco Mallmann

    2011-01-01

    The measurement of boreholes with diameters smaller than 500 pm is a demanding task that cannot be performed using state-of-the-art production metrology.In this letter,a miniaturized fiber probe with a diameter of 80 pm is presented.A probe is used for low-coherence interferometry to conduct highly precise measurements of form deviations of small boreholes.Measurements conducted in nozzles are also presented.The results prove the potential of the fiber-optical sensor for quality inspection of high-precision parts,such as injection nozzles,for common-rail diesel engines.

  8. HIGH SPEED INJECTION MOLDING OF HIGH DENSITY POLYETHYLENE - EFFECTS OF INJECTION SPEED ON STRUCTURE AND PROPERTIES

    Institute of Scientific and Technical Information of China (English)

    Kun Jiang; Feng Chen; Qiang Fu; Fei-long Yu; Run Su; Jing-hui Yang; Tian-nan Zhou; Jian Gao; Hua Deng; Ke Wang; Qin Zhang

    2011-01-01

    Thin wall samples of high density polyethylene (HDPE) were prepared via injection molding with differentinjection speeds ranging from 100 mm/s to 1200 mm/s. A significant decrease in the tensile strength and Young's moduluswas observed with increasing injection speed. In order to investigate the mechanism behind this decrease, the orientation,molecular weight, molecular weight distribution, melt flow rate, crystallinity and crystal morphology of HDPE werecharacterized using two-dimensional wide-angle X-ray diffraction (2D-WAXD), gel permeation chromatography (GPC),capillary rheometry and differential scanning calorimetry (DSC), respectively. It is demonstrated that the orientation,molecular weight, molecular weight distribution, melt flow rate and crystallinity have no obvious change with increasinginjection speed. Nevertheless, the content of extended chain crystals or large folded chain crystals was found to decreasewith increasing injection speed. Therefore, it is concluded that the decrease in tensile properties is mainly contributed by the reduced content of extended chain crystals or large folded chain crystals. This study provides industry with valuableinformation for the application of high speed injection molding.

  9. High Current Density, Long Life Cathodes for High Power RF Sources

    Energy Technology Data Exchange (ETDEWEB)

    Ives, Robert Lawrence [Calabazas Creek Research,, Inc.; Collins, George [Calabazas Creek Research, Inc.; Falce, Lou [Consultant; Schwartzkopf, Steve [Ron Witherspoon, Inc.; Busbaher, Daniel [Semicon Associates

    2014-01-22

    This program was tasked with improving the quality and expanding applications for Controlled Porosity Reservoir (CPR) cathodes. Calabazas Creek Research, Inc. (CCR) initially developed CPR cathodes on a DOE-funded SBIR program to improve cathodes for magnetron injection guns. Subsequent funding was received from the Defense Advanced Research Projects Agency. The program developed design requirements for implementation of the technology into high current density cathodes for high frequency applications. During Phase I of this program, CCR was awarded the prestigious 2011 R&D100 award for this technology. Subsequently, the technology was presented at numerous technical conferences. A patent was issued for the technology in 2009. These cathodes are now marketed by Semicon Associates, Inc. in Lexington, KY. They are the world’s largest producer of cathodes for vacuum electron devices. During this program, CCR teamed with Semicon Associates, Inc. and Ron Witherspoon, Inc. to improve the fabrication processes and expand applications for the cathodes. Specific fabrications issues included the quality of the wire winding that provides the basic structure and the sintering to bond the wires into a robust, cohesive structure. The program also developed improved techniques for integrating the resulting material into cathodes for electron guns.

  10. STUDY ON HIGH WELD STRENGTH OF IMPACT PROPYLENE COPOLYMER/HIGH DENSITY POLYETHYLENE LAMINATES

    Institute of Scientific and Technical Information of China (English)

    Chun-hui Zhang; Rui-fen Chen; Feng Chen; Yong-gang Shangguan; Qiang Zheng; Guo-hua Hu

    2011-01-01

    The impact propylene copolymer (IPC) and isotactic polypropylene (iPP) were separately selected to prepare laminates with high density polyethylene (HDPE) by hot press. The peel forces of IPC/HDPE and iPP/HDPE laminates were examined, and it was found that the welded joint strength in IPC/HDPE laminate was dramatically higher than that of iPP/HDPE laminate. According to the special microstructure of IPC, the co-crystallization of the ethylene segments in ethylene-propylene block copolymer (EbP) component of IPC and the PE chain in HDPE was proposed to explain the highstrength welding. The DSC results indicated that there indeed existed some interaction between IPC and HDPE, and the crystallizable PE component in IPC could affect the crystallization of HDPE. The scanning electron microscope (SEM) observations of IPC/HDPE blends demonstrated that HDPE tended to stay with the PE-rich EbP chains to form the dispersed phase, indicating the good miscibility between HDPE and EbP components of IPC. According to the above results, the effect of co-crystallization of the PE components of theIPC and HDPE on the high weld strength of IPC/HDPE laminate was confirmed.

  11. High-resolution spectroscopy and high-density monitoring in X-rays of Novae

    CERN Document Server

    Ness, Jan-Uwe

    2012-01-01

    The 21st century X-ray observatories XMM-Newton, Chandra, and Swift gave us completely new insights into the X-ray behaviour of nova outbursts. These new-generation X-ray observatories provide particularly high spectral resolution and high density in monitoring campaigns, simultaneously in X-rays and UV/optical. The entire evolution of several nova outbursts has been observed with the Swift XRT and UVOT instruments, allowing studies of the gradual shift of the peak of the SED from UV to X-rays, time scales to the onset and duration of the X-ray brightest supersoft source (SSS) phase, and pre- and post-SSS X-ray emission. In addition, XMM-Newton and Chandra observations can efficiently be scheduled, allowing deeper studies of strategically chosen evolutionary stages. Before Swift joined in 2005, Chandra and XMM-Newton blind shots in search of SSS emission unavoidably led to some underexposed observations taken before and/or after the SSS phase. More systematic Swift studies reduced this number while increasing...

  12. Fiber-Optic Terahertz Data-Communication Networks

    Science.gov (United States)

    Chua, Peter L.; Lambert, James L.; Morookian, John M.; Bergman, Larry A.

    1994-01-01

    Network protocols implemented in optical domain. Fiber-optic data-communication networks utilize fully available bandwidth of single-mode optical fibers. Two key features of method: use of subpicosecond laser pulses as carrier signals and spectral phase modulation of pulses for optical implementation of code-division multiple access as multiplexing network protocol. Local-area network designed according to concept offers full crossbar functionality, security of data in transit through network, and capacity about 100 times that of typical fiber-optic local-area network in current use.

  13. Ionic Wind Phenomenon and Charge Carrier Mobility in Very High Density Argon Corona Discharge Plasma

    Science.gov (United States)

    Nur, M.; Bonifaci, N.; Denat, A.

    2014-04-01

    Wind ions phenomenon has been observed in the high density argon corona discharge plasma. Corona discharge plasma was produced by point to plane electrodes and high voltage DC. Light emission from the recombination process was observed visually. The light emission proper follow the electric field lines that occur between point and plane electrodes. By using saturation current, the mobilities of non-thermal electrons and ions have been obtained in argon gas and liquid with variation of density from 2,5 1021 to 2 1022 cm-3. In the case of ions, we found that the behaviour of the apparent mobility inversely proportional to the density or follow the Langevin variation law. For non-thermal electron, mobility decreases and approximately follows a variation of Langevin type until the density <= 0,25 the critical density of argon.

  14. Effects of discharge current and voltage on the high density of metastable helium atoms

    Institute of Scientific and Technical Information of China (English)

    FengXian-Ping; DAndruczyk; BWJames; KTakiyama; SNamba; TOda

    2003-01-01

    Both hollow-cathode and Penning-type discharges were adopted toexcite helium atoms to a metastable state. Experimental data indicate that Penning discharge is more suitable for generating high fractions of metastables in a low-density helium hean for laser-induced fluorescence technique in measuring electric fields at the edge of a plasma. The metastable density increases with increasing helium gas pressure in the range of 1.33×10-2-66.7Pa. The highest metastable density of 3.8×1016m-3 is observed at a static gas pressure of 66.7Pa. An approximately linear relationship between the density of metastable helium atoms and the plasma discharge current is observed. Magnetic field plays a very important role in producing a high density of metastable atoms in Penning discharge.

  15. Effects of discharge current and voltage on the high density of metastable helium atoms

    Institute of Scientific and Technical Information of China (English)

    Feng Xian-Ping(冯贤平); D Andruczyk; B W James; K Takiyama; S Namba; T Oda

    2003-01-01

    Both hollow-cathode and Penning-type discharges were adopted to excite helium atoms to a metastable state.Experimental data indicate that Penning discharge is more suitable for generating high fractions of metastables in a low-density helium beam for laser-induced fluorescence technique in measuring electric fields at the edge of a plasma.The metastable density increases with increasing helium gas pressure in the range of 1.33× 10-2-66.7Pa. The highest metastable density of 3.8 × 1016m-3 is observed at a static gas pressure of 66.7Pa. An approximately linear relationship between the density of metastable helium atoms and the plasma discharge current is observed. Magnetic field plays a very important role in producing a high density of metastable atoms in Penning discharge.

  16. Density manifolds, geometric measures and high-energy physics in transfinite dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Nada, S.I. [Mathematics Department, Faculty of Science, Qatar University, Doha (Qatar)], E-mail: snada@qu.edu.qa

    2009-11-15

    We discuss certain manifolds with density. Furthermore, we outline natural connections leading to E-infinity theory and high-energy physics from a geometric measure and transfinite dimensional theoretical viewpoints.

  17. Single Crystal Piezoelectric Deformable Mirrors with High Actuator Density and Large Stroke Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Single crystal piezoelectric deformable mirrors with high actuator density, fine pitch, large stroke and no floating wires will be developed for future NASA science...

  18. Foundations of high-energy-density physics physical processes of matter at extreme conditions

    CERN Document Server

    Larsen, Jon

    2017-01-01

    High-energy-density physics explores the dynamics of matter at extreme conditions. This encompasses temperatures and densities far greater than we experience on Earth. It applies to normal stars, exploding stars, active galaxies, and planetary interiors. High-energy-density matter is found on Earth in the explosion of nuclear weapons and in laboratories with high-powered lasers or pulsed-power machines. The physics explored in this book is the basis for large-scale simulation codes needed to interpret experimental results whether from astrophysical observations or laboratory-scale experiments. The key elements of high-energy-density physics covered are gas dynamics, ionization, thermal energy transport, and radiation transfer, intense electromagnetic waves, and their dynamical coupling. Implicit in this is a fundamental understanding of hydrodynamics, plasma physics, atomic physics, quantum mechanics, and electromagnetic theory. Beginning with a summary of the topics and exploring the major ones in depth, thi...

  19. Assessing the functional properties of high-density lipoproteins : an emerging concept in cardiovascular research

    NARCIS (Netherlands)

    Triolo, Michela; Annema, Wijtske; Dullaart, Robin P. F.; Tietge, Uwe J. F.

    2013-01-01

    Although plasma concentrations of high-density lipoprotein (HDL) cholesterol correlate inversely with the incidence of atherosclerotic cardiovascular disease, results from recent epidemiological, genetic and pharmacological intervention studies resulted in a shift of concept. Rather than HDL cholest

  20. High Density Lipoproteins and Arteriosclerosis: Role of Cholesterol Efflux and Reverse Cholesterol Transport

    National Research Council Canada - National Science Library

    von Eckardstein, Arnold; Nofer, Jerzy Roch; Assmann, Gerd

    2001-01-01

    Abstract—High density lipoprotein (HDL) cholesterol is an important risk factor for coronary heart disease, and HDL exerts various potentially antiatherogenic properties, including the mediation of reverse transport of cholesterol...