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Sample records for high accuracy integrated

  1. Two high accuracy digital integrators for Rogowski current transducers

    Science.gov (United States)

    Luo, Pan-dian; Li, Hong-bin; Li, Zhen-hua

    2014-01-01

    The Rogowski current transducers have been widely used in AC current measurement, but their accuracy is mainly subject to the analog integrators, which have typical problems such as poor long-term stability and being susceptible to environmental conditions. The digital integrators can be another choice, but they cannot obtain a stable and accurate output for the reason that the DC component in original signal can be accumulated, which will lead to output DC drift. Unknown initial conditions can also result in integral output DC offset. This paper proposes two improved digital integrators used in Rogowski current transducers instead of traditional analog integrators for high measuring accuracy. A proportional-integral-derivative (PID) feedback controller and an attenuation coefficient have been applied in improving the Al-Alaoui integrator to change its DC response and get an ideal frequency response. For the special design in the field of digital signal processing, the improved digital integrators have better performance than analog integrators. Simulation models are built for the purpose of verification and comparison. The experiments prove that the designed integrators can achieve higher accuracy than analog integrators in steady-state response, transient-state response, and temperature changing condition.

  2. Integral equation models for image restoration: high accuracy methods and fast algorithms

    International Nuclear Information System (INIS)

    Lu, Yao; Shen, Lixin; Xu, Yuesheng

    2010-01-01

    Discrete models are consistently used as practical models for image restoration. They are piecewise constant approximations of true physical (continuous) models, and hence, inevitably impose bottleneck model errors. We propose to work directly with continuous models for image restoration aiming at suppressing the model errors caused by the discrete models. A systematic study is conducted in this paper for the continuous out-of-focus image models which can be formulated as an integral equation of the first kind. The resulting integral equation is regularized by the Lavrentiev method and the Tikhonov method. We develop fast multiscale algorithms having high accuracy to solve the regularized integral equations of the second kind. Numerical experiments show that the methods based on the continuous model perform much better than those based on discrete models, in terms of PSNR values and visual quality of the reconstructed images

  3. High-accuracy numerical integration of charged particle motion – with application to ponderomotive force

    International Nuclear Information System (INIS)

    Furukawa, Masaru; Ohkawa, Yushiro; Matsuyama, Akinobu

    2016-01-01

    A high-accuracy numerical integration algorithm for a charged particle motion is developed. The algorithm is based on the Hamiltonian mechanics and the operator decomposition. The algorithm is made to be time-reversal symmetric, and its order of accuracy can be increased to any order by using a recurrence formula. One of the advantages is that it is an explicit method. An effective way to decompose the time evolution operator is examined; the Poisson tensor is decomposed and non-canonical variables are adopted. The algorithm is extended to a time dependent fields' case by introducing the extended phase space. Numerical tests showing the performance of the algorithm are presented. One is the pure cyclotron motion for a long time period, and the other is a charged particle motion in a rapidly oscillating field. (author)

  4. Depth extraction method with high accuracy in integral imaging based on moving array lenslet technique

    Science.gov (United States)

    Wang, Yao-yao; Zhang, Juan; Zhao, Xue-wei; Song, Li-pei; Zhang, Bo; Zhao, Xing

    2018-03-01

    In order to improve depth extraction accuracy, a method using moving array lenslet technique (MALT) in pickup stage is proposed, which can decrease the depth interval caused by pixelation. In this method, the lenslet array is moved along the horizontal and vertical directions simultaneously for N times in a pitch to get N sets of elemental images. Computational integral imaging reconstruction method for MALT is taken to obtain the slice images of the 3D scene, and the sum modulus (SMD) blur metric is taken on these slice images to achieve the depth information of the 3D scene. Simulation and optical experiments are carried out to verify the feasibility of this method.

  5. Development of a switched integrator amplifier for high-accuracy optical measurements

    International Nuclear Information System (INIS)

    Mountford, John; Porrovecchio, Geiland; Smid, Marek; Smid, Radislav

    2008-01-01

    In the field of low flux optical measurements, the development and use of large area silicon detectors is becoming more frequent. The current/voltage conversion of their photocurrent presents a set of problems for traditional transimpedance amplifiers. The switched integration principle overcomes these limitations. We describe the development of a fully characterized current-voltage amplifier using the switched integrator technique. Two distinct systems have been developed in parallel at the United Kingdom's National Physical Laboratory (NPL) and Czech Metrology Institute (CMI) laboratories. We present the circuit theory and best practice in the design and construction of switched integrators. In conclusion the results achieved and future developments are discussed

  6. Development of a switched integrator amplifier for high-accuracy optical measurements.

    Science.gov (United States)

    Mountford, John; Porrovecchio, Geiland; Smid, Marek; Smid, Radislav

    2008-11-01

    In the field of low flux optical measurements, the development and use of large area silicon detectors is becoming more frequent. The current/voltage conversion of their photocurrent presents a set of problems for traditional transimpedance amplifiers. The switched integration principle overcomes these limitations. We describe the development of a fully characterized current-voltage amplifier using the switched integrator technique. Two distinct systems have been developed in parallel at the United Kingdom's National Physical Laboratory (NPL) and Czech Metrology Institute (CMI) laboratories. We present the circuit theory and best practice in the design and construction of switched integrators. In conclusion the results achieved and future developments are discussed.

  7. High construal level can help negotiators to reach integrative agreements: The role of information exchange and judgement accuracy.

    Science.gov (United States)

    Wening, Stefanie; Keith, Nina; Abele, Andrea E

    2016-06-01

    In negotiations, a focus on interests (why negotiators want something) is key to integrative agreements. Yet, many negotiators spontaneously focus on positions (what they want), with suboptimal outcomes. Our research applies construal-level theory to negotiations and proposes that a high construal level instigates a focus on interests during negotiations which, in turn, positively affects outcomes. In particular, we tested the notion that the effect of construal level on outcomes was mediated by information exchange and judgement accuracy. Finally, we expected the mere mode of presentation of task material to affect construal levels and manipulated construal levels using concrete versus abstract negotiation tasks. In two experiments, participants negotiated in dyads in either a high- or low-construal-level condition. In Study 1, high-construal-level dyads outperformed dyads in the low-construal-level condition; this main effect was mediated by information exchange. Study 2 replicated both the main and mediation effects using judgement accuracy as mediator and additionally yielded a positive effect of a high construal level on a second, more complex negotiation task. These results not only provide empirical evidence for the theoretically proposed link between construal levels and negotiation outcomes but also shed light on the processes underlying this effect. © 2015 The British Psychological Society.

  8. Cost-effective improvements of a rotating platform by integration of a high-accuracy inclinometer and encoders for attitude evaluation

    International Nuclear Information System (INIS)

    Wen, Chenyang; He, Shengyang; Hu, Peida; Bu, Changgen

    2017-01-01

    Attitude heading reference systems (AHRSs) based on micro-electromechanical system (MEMS) inertial sensors are widely used because of their low cost, light weight, and low power. However, low-cost AHRSs suffer from large inertial sensor errors. Therefore, experimental performance evaluation of MEMS-based AHRSs after system implementation is necessary. High-accuracy turntables can be used to verify the performance of MEMS-based AHRSs indoors, but they are expensive and unsuitable for outdoor tests. This study developed a low-cost two-axis rotating platform for indoor and outdoor attitude determination. A high-accuracy inclinometer and encoders were integrated into the platform to improve the achievable attitude test accuracy. An attitude error compensation method was proposed to calibrate the initial attitude errors caused by the movements and misalignment angles of the platform. The proposed attitude error determination method was examined through rotating experiments, which showed that the standard deviations of the pitch and roll errors were 0.050° and 0.090°, respectively. The pitch and roll errors both decreased to 0.024° when the proposed attitude error determination method was used. This decrease validates the effectiveness of the compensation method. Experimental results demonstrated that the integration of the inclinometer and encoders improved the performance of the low-cost, two-axis, rotating platform in terms of attitude accuracy. (paper)

  9. A New Image Processing Procedure Integrating PCI-RPC and ArcGIS-Spline Tools to Improve the Orthorectification Accuracy of High-Resolution Satellite Imagery

    Directory of Open Access Journals (Sweden)

    Hongying Zhang

    2016-10-01

    Full Text Available Given the low accuracy of the traditional remote sensing image processing software when orthorectifying satellite images that cover mountainous areas, and in order to make a full use of mutually compatible and complementary characteristics of the remote sensing image processing software PCI-RPC (Rational Polynomial Coefficients and ArcGIS-Spline, this study puts forward a new operational and effective image processing procedure to improve the accuracy of image orthorectification. The new procedure first processes raw image data into an orthorectified image using PCI with RPC model (PCI-RPC, and then the orthorectified image is further processed using ArcGIS with the Spline tool (ArcGIS-Spline. We used the high-resolution CBERS-02C satellite images (HR1 and HR2 scenes with a pixel size of 2 m acquired from Yangyuan County in Hebei Province of China to test the procedure. In this study, when separately using PCI-RPC and ArcGIS-Spline tools directly to process the HR1/HR2 raw images, the orthorectification accuracies (root mean square errors, RMSEs for HR1/HR2 images were 2.94 m/2.81 m and 4.65 m/4.41 m, respectively. However, when using our newly proposed procedure, the corresponding RMSEs could be reduced to 1.10 m/1.07 m. The experimental results demonstrated that the new image processing procedure which integrates PCI-RPC and ArcGIS-Spline tools could significantly improve image orthorectification accuracy. Therefore, in terms of practice, the new procedure has the potential to use existing software products to easily improve image orthorectification accuracy.

  10. High accuracy FIONA-AFM hybrid imaging

    International Nuclear Information System (INIS)

    Fronczek, D.N.; Quammen, C.; Wang, H.; Kisker, C.; Superfine, R.; Taylor, R.; Erie, D.A.; Tessmer, I.

    2011-01-01

    Multi-protein complexes are ubiquitous and play essential roles in many biological mechanisms. Single molecule imaging techniques such as electron microscopy (EM) and atomic force microscopy (AFM) are powerful methods for characterizing the structural properties of multi-protein and multi-protein-DNA complexes. However, a significant limitation to these techniques is the ability to distinguish different proteins from one another. Here, we combine high resolution fluorescence microscopy and AFM (FIONA-AFM) to allow the identification of different proteins in such complexes. Using quantum dots as fiducial markers in addition to fluorescently labeled proteins, we are able to align fluorescence and AFM information to ≥8 nm accuracy. This accuracy is sufficient to identify individual fluorescently labeled proteins in most multi-protein complexes. We investigate the limitations of localization precision and accuracy in fluorescence and AFM images separately and their effects on the overall registration accuracy of FIONA-AFM hybrid images. This combination of the two orthogonal techniques (FIONA and AFM) opens a wide spectrum of possible applications to the study of protein interactions, because AFM can yield high resolution (5-10 nm) information about the conformational properties of multi-protein complexes and the fluorescence can indicate spatial relationships of the proteins in the complexes. -- Research highlights: → Integration of fluorescent signals in AFM topography with high (<10 nm) accuracy. → Investigation of limitations and quantitative analysis of fluorescence-AFM image registration using quantum dots. → Fluorescence center tracking and display as localization probability distributions in AFM topography (FIONA-AFM). → Application of FIONA-AFM to a biological sample containing damaged DNA and the DNA repair proteins UvrA and UvrB conjugated to quantum dots.

  11. Integration of PET-CT and cone-beam CT for image-guided radiotherapy with high image quality and registration accuracy

    Science.gov (United States)

    Wu, T.-H.; Liang, C.-H.; Wu, J.-K.; Lien, C.-Y.; Yang, B.-H.; Huang, Y.-H.; Lee, J. J. S.

    2009-07-01

    Hybrid positron emission tomography-computed tomography (PET-CT) system enhances better differentiation of tissue uptake of 18F-fluorodeoxyglucose (18F-FDG) and provides much more diagnostic value in the non-small-cell lung cancer and nasopharyngeal carcinoma (NPC). In PET-CT, high quality CT images not only offer diagnostic value on anatomic delineation of the tissues but also shorten the acquisition time for attenuation correction (AC) compared with PET-alone imaging. The linear accelerators equipped with the X-ray cone-beam computed tomography (CBCT) imaging system for image-guided radiotherapy (IGRT) provides excellent verification on position setup error. The purposes of our study were to optimize the CT acquisition protocols of PET-CT and to integrate the PET-CT and CBCT for IGRT. The CT imaging parameters were modified in PET-CT for increasing the image quality in order to enhance the diagnostic value on tumour delineation. Reproducibility and registration accuracy via bone co-registration algorithm between the PET-CT and CBCT were evaluated by using a head phantom to simulate a head and neck treatment condition. Dose measurement in computed tomography dose index (CTDI) was also estimated. Optimization of the CT acquisition protocols of PET-CT was feasible in this study. Co-registration accuracy between CBCT and PET-CT on axial and helical modes was in the range of 1.06 to 2.08 and 0.99 to 2.05 mm, respectively. In our result, it revealed that the accuracy of the co-registration with CBCT on helical mode was more accurate than that on axial mode. Radiation doses in CTDI were 4.76 to 18.5 mGy and 4.83 to 18.79 mGy on axial and helical modes, respectively. Registration between PET-CT and CBCT is a state-of-the-art registration technology which could provide much information on diagnosis and accurate tumour contouring on radiotherapy while implementing radiotherapy procedures. This novelty technology of PET-CT and cone-beam CT integration for IGRT may have a

  12. Integration of PET-CT and cone-beam CT for image-guided radiotherapy with high image quality and registration accuracy

    International Nuclear Information System (INIS)

    Wu, T-H; Liang, C-H; Wu, J-K; Lien, C-Y; Yang, B-H; Lee, J J S; Huang, Y-H

    2009-01-01

    Hybrid positron emission tomography-computed tomography (PET-CT) system enhances better differentiation of tissue uptake of 18 F-fluorodeoxyglucose ( 18 F-FDG) and provides much more diagnostic value in the non-small-cell lung cancer and nasopharyngeal carcinoma (NPC). In PET-CT, high quality CT images not only offer diagnostic value on anatomic delineation of the tissues but also shorten the acquisition time for attenuation correction (AC) compared with PET-alone imaging. The linear accelerators equipped with the X-ray cone-beam computed tomography (CBCT) imaging system for image-guided radiotherapy (IGRT) provides excellent verification on position setup error. The purposes of our study were to optimize the CT acquisition protocols of PET-CT and to integrate the PET-CT and CBCT for IGRT. The CT imaging parameters were modified in PET-CT for increasing the image quality in order to enhance the diagnostic value on tumour delineation. Reproducibility and registration accuracy via bone co-registration algorithm between the PET-CT and CBCT were evaluated by using a head phantom to simulate a head and neck treatment condition. Dose measurement in computed tomography dose index (CTDI) was also estimated. Optimization of the CT acquisition protocols of PET-CT was feasible in this study. Co-registration accuracy between CBCT and PET-CT on axial and helical modes was in the range of 1.06 to 2.08 and 0.99 to 2.05 mm, respectively. In our result, it revealed that the accuracy of the co-registration with CBCT on helical mode was more accurate than that on axial mode. Radiation doses in CTDI were 4.76 to 18.5 mGy and 4.83 to 18.79 mGy on axial and helical modes, respectively. Registration between PET-CT and CBCT is a state-of-the-art registration technology which could provide much information on diagnosis and accurate tumour contouring on radiotherapy while implementing radiotherapy procedures. This novelty technology of PET-CT and cone-beam CT integration for IGRT may have a

  13. High current high accuracy IGBT pulse generator

    International Nuclear Information System (INIS)

    Nesterov, V.V.; Donaldson, A.R.

    1995-05-01

    A solid state pulse generator capable of delivering high current triangular or trapezoidal pulses into an inductive load has been developed at SLAC. Energy stored in a capacitor bank of the pulse generator is switched to the load through a pair of insulated gate bipolar transistors (IGBT). The circuit can then recover the remaining energy and transfer it back to the capacitor bank without reversing the capacitor voltage. A third IGBT device is employed to control the initial charge to the capacitor bank, a command charging technique, and to compensate for pulse to pulse power losses. The rack mounted pulse generator contains a 525 μF capacitor bank. It can deliver 500 A at 900V into inductive loads up to 3 mH. The current amplitude and discharge time are controlled to 0.02% accuracy by a precision controller through the SLAC central computer system. This pulse generator drives a series pair of extraction dipoles

  14. High accuracy step gauge interferometer

    Science.gov (United States)

    Byman, V.; Jaakkola, T.; Palosuo, I.; Lassila, A.

    2018-05-01

    Step gauges are convenient transfer standards for the calibration of coordinate measuring machines. A novel interferometer for step gauge calibrations implemented at VTT MIKES is described. The four-pass interferometer follows Abbe’s principle and measures the position of the inductive probe attached to a measuring head. The measuring head of the instrument is connected to a balanced boom above the carriage by a piezo translation stage. A key part of the measuring head is an invar structure on which the inductive probe and the corner cubes of the measuring arm of the interferometer are attached. The invar structure can be elevated so that the probe is raised without breaking the laser beam. During probing, the bending of the probe and the interferometer readings are recorded and the measurement face position is extrapolated to zero force. The measurement process is fully automated and the face positions of the steps can be measured up to a length of 2 m. Ambient conditions are measured continuously and the refractive index of air is compensated for. Before measurements the step gauge is aligned with an integrated 2D coordinate measuring system. The expanded uncertainty of step gauge calibration is U=\\sqrt{{{(64 nm)}2}+{{(88× {{10}-9}L)}2}} .

  15. Improved patient repositioning accuracy by integrating an additional jaw fixation into a high precision face mask system in stereotactic radiotherapy of the head

    International Nuclear Information System (INIS)

    Lopatta, E.; Liesenfeld, S.M.; Bank, P.; Guenther, R.; Wiezorek, T.; Wendt, T.G.; Wurm, R.

    2003-01-01

    Background: For high precision radiotherapy of the neurocranium a precise, reproducible positioning technique is the basic pre-requisite. The aim of this study was to assess the influence of a modification of the commercially available stereotactical BrainLab trademark -head mask system on accuracy in patient positioning during fractionated radiotherapy. Material and Methods: 29 patients were treated with stereotactic radiotherapy of the head. Immobilization was provided by a two layer thermoplastic mask system (BrainLab trademark). 18 of these patients received an additional custom made fixation either of the upper jaw (OKF) or of the mandibula (UKF). The positioning accuracy was assessed by measurements of the shifting of anatomical landmarks in relation to therigid mask system on biplanar simulator films using a digital imaging system. Before each measurement a fine adjustment of the simulator to an optical ring system was performed. The reference radiographs were done just before CT-planning. During a 2-7 weeks lasting course of radiotherapy displacement measurements in relation to the reference images for all three dimensions (z, y and x) were done once a week. In 29 patients 844 measurements were analyzed. Results: An additional jaw fixation improves the reproducibility of patient positioning significantly in all three spatial dimensions. The standard deviation in lateral direction (x) was 0.6 mm with jaw fixation vs. 0.7 mm without jaw fixation (p [de

  16. High Accuracy Transistor Compact Model Calibrations

    Energy Technology Data Exchange (ETDEWEB)

    Hembree, Charles E. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Mar, Alan [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Robertson, Perry J. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)

    2015-09-01

    Typically, transistors are modeled by the application of calibrated nominal and range models. These models consists of differing parameter values that describe the location and the upper and lower limits of a distribution of some transistor characteristic such as current capacity. Correspond- ingly, when using this approach, high degrees of accuracy of the transistor models are not expected since the set of models is a surrogate for a statistical description of the devices. The use of these types of models describes expected performances considering the extremes of process or transistor deviations. In contrast, circuits that have very stringent accuracy requirements require modeling techniques with higher accuracy. Since these accurate models have low error in transistor descriptions, these models can be used to describe part to part variations as well as an accurate description of a single circuit instance. Thus, models that meet these stipulations also enable the calculation of quantifi- cation of margins with respect to a functional threshold and uncertainties in these margins. Given this need, new model high accuracy calibration techniques for bipolar junction transis- tors have been developed and are described in this report.

  17. High accuracy 3-D laser radar

    DEFF Research Database (Denmark)

    Busck, Jens; Heiselberg, Henning

    2004-01-01

    We have developed a mono-static staring 3-D laser radar based on gated viewing with range accuracy below 1 m at 10 m and 1 cm at 100. We use a high sensitivity, fast, intensified CCD camera, and a Nd:Yag passively Q-switched 32.4 kHz pulsed green laser at 532 nm. The CCD has 752x582 pixels. Camera...

  18. High accuracy satellite drag model (HASDM)

    Science.gov (United States)

    Storz, Mark F.; Bowman, Bruce R.; Branson, Major James I.; Casali, Stephen J.; Tobiska, W. Kent

    The dominant error source in force models used to predict low-perigee satellite trajectories is atmospheric drag. Errors in operational thermospheric density models cause significant errors in predicted satellite positions, since these models do not account for dynamic changes in atmospheric drag for orbit predictions. The Air Force Space Battlelab's High Accuracy Satellite Drag Model (HASDM) estimates and predicts (out three days) a dynamically varying global density field. HASDM includes the Dynamic Calibration Atmosphere (DCA) algorithm that solves for the phases and amplitudes of the diurnal and semidiurnal variations of thermospheric density near real-time from the observed drag effects on a set of Low Earth Orbit (LEO) calibration satellites. The density correction is expressed as a function of latitude, local solar time and altitude. In HASDM, a time series prediction filter relates the extreme ultraviolet (EUV) energy index E10.7 and the geomagnetic storm index ap, to the DCA density correction parameters. The E10.7 index is generated by the SOLAR2000 model, the first full spectrum model of solar irradiance. The estimated and predicted density fields will be used operationally to significantly improve the accuracy of predicted trajectories for all low-perigee satellites.

  19. Fast and High Accuracy Wire Scanner

    CERN Document Server

    Koujili, M; Koopman, J; Ramos, D; Sapinski, M; De Freitas, J; Ait Amira, Y; Djerdir, A

    2009-01-01

    Scanning of a high intensity particle beam imposes challenging requirements on a Wire Scanner system. It is expected to reach a scanning speed of 20 m.s-1 with a position accuracy of the order of 1 μm. In addition a timing accuracy better than 1 millisecond is needed. The adopted solution consists of a fork holding a wire rotating by a maximum of 200°. Fork, rotor and angular position sensor are mounted on the same axis and located in a chamber connected to the beam vacuum. The requirements imply the design of a system with extremely low vibration, vacuum compatibility, radiation and temperature tolerance. The adopted solution consists of a rotary brushless synchronous motor with the permanent magnet rotor installed inside of the vacuum chamber and the stator installed outside. The accurate position sensor will be mounted on the rotary shaft inside of the vacuum chamber, has to resist a bake-out temperature of 200°C and ionizing radiation up to a dozen of kGy/year. A digital feedback controller allows maxi...

  20. Gamma-Ray Peak Integration: Accuracy and Precision

    International Nuclear Information System (INIS)

    Richard M. Lindstrom

    2000-01-01

    The accuracy of singlet gamma-ray peak areas obtained by a peak analysis program is immaterial. If the same algorithm is used for sample measurement as for calibration and if the peak shapes are similar, then biases in the integration method cancel. Reproducibility is the only important issue. Even the uncertainty of the areas computed by the program is trivial because the true standard uncertainty can be experimentally assessed by repeated measurements of the same source. Reproducible peak integration was important in a recent standard reference material certification task. The primary tool used for spectrum analysis was SUM, a National Institute of Standards and Technology interactive program to sum peaks and subtract a linear background, using the same channels to integrate all 20 spectra. For comparison, this work examines other peak integration programs. Unlike some published comparisons of peak performance in which synthetic spectra were used, this experiment used spectra collected for a real (though exacting) analytical project, analyzed by conventional software used in routine ways. Because both components of the 559- to 564-keV doublet are from 76 As, they were integrated together with SUM. The other programs, however, deconvoluted the peaks. A sensitive test of the fitting algorithm is the ratio of reported peak areas. In almost all the cases, this ratio was much more variable than expected from the reported uncertainties reported by the program. Other comparisons to be reported indicate that peak integration is still an imperfect tool in the analysis of gamma-ray spectra

  1. Electron ray tracing with high accuracy

    International Nuclear Information System (INIS)

    Saito, K.; Okubo, T.; Takamoto, K.; Uno, Y.; Kondo, M.

    1986-01-01

    An electron ray tracing program is developed to investigate the overall geometrical and chromatic aberrations in electron optical systems. The program also computes aberrations due to manufacturing errors in lenses and deflectors. Computation accuracy is improved by (1) calculating electrostatic and magnetic scalar potentials using the finite element method with third-order isoparametric elements, and (2) solving the modified ray equation which the aberrations satisfy. Computation accuracy of 4 nm is achieved for calculating optical properties of the system with an electrostatic lens

  2. High accuracy in silico sulfotransferase models.

    Science.gov (United States)

    Cook, Ian; Wang, Ting; Falany, Charles N; Leyh, Thomas S

    2013-11-29

    Predicting enzymatic behavior in silico is an integral part of our efforts to understand biology. Hundreds of millions of compounds lie in targeted in silico libraries waiting for their metabolic potential to be discovered. In silico "enzymes" capable of accurately determining whether compounds can inhibit or react is often the missing piece in this endeavor. This problem has now been solved for the cytosolic sulfotransferases (SULTs). SULTs regulate the bioactivities of thousands of compounds--endogenous metabolites, drugs and other xenobiotics--by transferring the sulfuryl moiety (SO3) from 3'-phosphoadenosine 5'-phosphosulfate to the hydroxyls and primary amines of these acceptors. SULT1A1 and 2A1 catalyze the majority of sulfation that occurs during human Phase II metabolism. Here, recent insights into the structure and dynamics of SULT binding and reactivity are incorporated into in silico models of 1A1 and 2A1 that are used to identify substrates and inhibitors in a structurally diverse set of 1,455 high value compounds: the FDA-approved small molecule drugs. The SULT1A1 models predict 76 substrates. Of these, 53 were known substrates. Of the remaining 23, 21 were tested, and all were sulfated. The SULT2A1 models predict 22 substrates, 14 of which are known substrates. Of the remaining 8, 4 were tested, and all are substrates. The models proved to be 100% accurate in identifying substrates and made no false predictions at Kd thresholds of 100 μM. In total, 23 "new" drug substrates were identified, and new linkages to drug inhibitors are predicted. It now appears to be possible to accurately predict Phase II sulfonation in silico.

  3. RTX Correction Accuracy and Real-Time Data Processing of the New Integrated SeismoGeodetic System with Real-Time Acceleration and Displacement Measurements for Earthquake Characterization Based on High-Rate Seismic and GPS Data

    Science.gov (United States)

    Zimakov, L. G.; Raczka, J.; Barrientos, S. E.

    2016-12-01

    We will discuss and show the results obtained from an integrated SeismoGeodetic System, model SG160-09, installed in the Chile (Chilean National Network), Italy (University of Naples Network), and California. The SG160-09 provides the user high rate GNSS and accelerometer data, full epoch-by-epoch measurement integrity and the ability to create combined GNSS and accelerometer high-rate (200Hz) displacement time series in real-time. The SG160-09 combines seismic recording with GNSS geodetic measurement in a single compact, ruggedized case. The system includes a low-power, 220-channel GNSS receiver powered by the latest Trimble-precise Maxwell™6 technology and supports tracking GPS, GLONASS and Galileo signals. The receiver incorporates on-board GNSS point positioning using Real-Time Precise Point Positioning (PPP) technology with satellite clock and orbit corrections delivered over IP networks. The seismic recording includes an ANSS Class A, force balance accelerometer with the latest, low power, 24-bit A/D converter, producing high-resolution seismic data. The SG160-09 processor acquires and packetizes both seismic and geodetic data and transmits it to the central station using an advanced, error-correction protocol providing data integrity between the field and the processing center. The SG160-09 has been installed in three seismic stations in different geographic locations with different Trimble global reference stations coverage The hardware includes the SG160-09 system, external Zephyr Geodetic-2 GNSS antenna, both radio and high-speed Internet communication media. Both acceleration and displacement data was transmitted in real-time to the centralized Data Acquisition Centers for real-time data processing. Command/Control of the field station and real-time GNSS position correction are provided via the Pivot platform. Data from the SG160-09 system was used for seismic event characterization along with data from traditional seismic and geodetic stations

  4. High accuracy autonomous navigation using the global positioning system (GPS)

    Science.gov (United States)

    Truong, Son H.; Hart, Roger C.; Shoan, Wendy C.; Wood, Terri; Long, Anne C.; Oza, Dipak H.; Lee, Taesul

    1997-01-01

    The application of global positioning system (GPS) technology to the improvement of the accuracy and economy of spacecraft navigation, is reported. High-accuracy autonomous navigation algorithms are currently being qualified in conjunction with the GPS attitude determination flyer (GADFLY) experiment for the small satellite technology initiative Lewis spacecraft. Preflight performance assessments indicated that these algorithms are able to provide a real time total position accuracy of better than 10 m and a velocity accuracy of better than 0.01 m/s, with selective availability at typical levels. It is expected that the position accuracy will be increased to 2 m if corrections are provided by the GPS wide area augmentation system.

  5. Systematic Calibration for Ultra-High Accuracy Inertial Measurement Units

    Directory of Open Access Journals (Sweden)

    Qingzhong Cai

    2016-06-01

    Full Text Available An inertial navigation system (INS has been widely used in challenging GPS environments. With the rapid development of modern physics, an atomic gyroscope will come into use in the near future with a predicted accuracy of 5 × 10−6°/h or better. However, existing calibration methods and devices can not satisfy the accuracy requirements of future ultra-high accuracy inertial sensors. In this paper, an improved calibration model is established by introducing gyro g-sensitivity errors, accelerometer cross-coupling errors and lever arm errors. A systematic calibration method is proposed based on a 51-state Kalman filter and smoother. Simulation results show that the proposed calibration method can realize the estimation of all the parameters using a common dual-axis turntable. Laboratory and sailing tests prove that the position accuracy in a five-day inertial navigation can be improved about 8% by the proposed calibration method. The accuracy can be improved at least 20% when the position accuracy of the atomic gyro INS can reach a level of 0.1 nautical miles/5 d. Compared with the existing calibration methods, the proposed method, with more error sources and high order small error parameters calibrated for ultra-high accuracy inertial measurement units (IMUs using common turntables, has a great application potential in future atomic gyro INSs.

  6. MUSCLE: multiple sequence alignment with high accuracy and high throughput.

    Science.gov (United States)

    Edgar, Robert C

    2004-01-01

    We describe MUSCLE, a new computer program for creating multiple alignments of protein sequences. Elements of the algorithm include fast distance estimation using kmer counting, progressive alignment using a new profile function we call the log-expectation score, and refinement using tree-dependent restricted partitioning. The speed and accuracy of MUSCLE are compared with T-Coffee, MAFFT and CLUSTALW on four test sets of reference alignments: BAliBASE, SABmark, SMART and a new benchmark, PREFAB. MUSCLE achieves the highest, or joint highest, rank in accuracy on each of these sets. Without refinement, MUSCLE achieves average accuracy statistically indistinguishable from T-Coffee and MAFFT, and is the fastest of the tested methods for large numbers of sequences, aligning 5000 sequences of average length 350 in 7 min on a current desktop computer. The MUSCLE program, source code and PREFAB test data are freely available at http://www.drive5. com/muscle.

  7. The diagnostic accuracy of integrated positron emission tomography ...

    African Journals Online (AJOL)

    The PET-CT findings, including maximum standardised uptake value (SUVmax), were compared with the gold standard (tissue or microbiological diagnosis). The sensitivity, specificity, positive and negative predictive values and diagnostic accuracy for malignant disease were calculated according to the SUVmax cut-off of ...

  8. Determination of UAV position using high accuracy navigation platform

    Directory of Open Access Journals (Sweden)

    Ireneusz Kubicki

    2016-07-01

    Full Text Available The choice of navigation system for mini UAV is very important because of its application and exploitation, particularly when the installed on it a synthetic aperture radar requires highly precise information about an object’s position. The presented exemplary solution of such a system draws attention to the possible problems associated with the use of appropriate technology, sensors, and devices or with a complete navigation system. The position and spatial orientation errors of the measurement platform influence on the obtained SAR imaging. Both, turbulences and maneuvers performed during flight cause the changes in the position of the airborne object resulting in deterioration or lack of images from SAR. Consequently, it is necessary to perform operations for reducing or eliminating the impact of the sensors’ errors on the UAV position accuracy. You need to look for compromise solutions between newer better technologies and in the field of software. Keywords: navigation systems, unmanned aerial vehicles, sensors integration

  9. High accuracy wavelength calibration for a scanning visible spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Scotti, Filippo; Bell, Ronald E. [Princeton Plasma Physics Laboratory, Princeton, New Jersey 08543 (United States)

    2010-10-15

    Spectroscopic applications for plasma velocity measurements often require wavelength accuracies {<=}0.2 A. An automated calibration, which is stable over time and environmental conditions without the need to recalibrate after each grating movement, was developed for a scanning spectrometer to achieve high wavelength accuracy over the visible spectrum. This method fits all relevant spectrometer parameters using multiple calibration spectra. With a stepping-motor controlled sine drive, an accuracy of {approx}0.25 A has been demonstrated. With the addition of a high resolution (0.075 arc sec) optical encoder on the grating stage, greater precision ({approx}0.005 A) is possible, allowing absolute velocity measurements within {approx}0.3 km/s. This level of precision requires monitoring of atmospheric temperature and pressure and of grating bulk temperature to correct for changes in the refractive index of air and the groove density, respectively.

  10. The use of low density high accuracy (LDHA) data for correction of high density low accuracy (HDLA) point cloud

    Science.gov (United States)

    Rak, Michal Bartosz; Wozniak, Adam; Mayer, J. R. R.

    2016-06-01

    Coordinate measuring techniques rely on computer processing of coordinate values of points gathered from physical surfaces using contact or non-contact methods. Contact measurements are characterized by low density and high accuracy. On the other hand optical methods gather high density data of the whole object in a short time but with accuracy at least one order of magnitude lower than for contact measurements. Thus the drawback of contact methods is low density of data, while for non-contact methods it is low accuracy. In this paper a method for fusion of data from two measurements of fundamentally different nature: high density low accuracy (HDLA) and low density high accuracy (LDHA) is presented to overcome the limitations of both measuring methods. In the proposed method the concept of virtual markers is used to find a representation of pairs of corresponding characteristic points in both sets of data. In each pair the coordinates of the point from contact measurements is treated as a reference for the corresponding point from non-contact measurement. Transformation enabling displacement of characteristic points from optical measurement to their match from contact measurements is determined and applied to the whole point cloud. The efficiency of the proposed algorithm was evaluated by comparison with data from a coordinate measuring machine (CMM). Three surfaces were used for this evaluation: plane, turbine blade and engine cover. For the planar surface the achieved improvement was of around 200 μm. Similar results were obtained for the turbine blade but for the engine cover the improvement was smaller. For both freeform surfaces the improvement was higher for raw data than for data after creation of mesh of triangles.

  11. High-accuracy measurements of the normal specular reflectance

    International Nuclear Information System (INIS)

    Voarino, Philippe; Piombini, Herve; Sabary, Frederic; Marteau, Daniel; Dubard, Jimmy; Hameury, Jacques; Filtz, Jean Remy

    2008-01-01

    The French Laser Megajoule (LMJ) is designed and constructed by the French Commissariata l'Energie Atomique (CEA). Its amplifying section needs highly reflective multilayer mirrors for the flash lamps. To monitor and improve the coating process, the reflectors have to be characterized to high accuracy. The described spectrophotometer is designed to measure normal specular reflectance with high repeatability by using a small spot size of 100 μm. Results are compared with ellipsometric measurements. The instrument can also perform spatial characterization to detect coating nonuniformity

  12. High accuracy 3D electromagnetic finite element analysis

    International Nuclear Information System (INIS)

    Nelson, E.M.

    1996-01-01

    A high accuracy 3D electromagnetic finite element field solver employing quadratic hexahedral elements and quadratic mixed-order one-form basis functions will be described. The solver is based on an object-oriented C++ class library. Test cases demonstrate that frequency errors less than 10 ppm can be achieved using modest workstations, and that the solutions have no contamination from spurious modes. The role of differential geometry and geometrical physics in finite element analysis will also be discussed

  13. High accuracy 3D electromagnetic finite element analysis

    International Nuclear Information System (INIS)

    Nelson, Eric M.

    1997-01-01

    A high accuracy 3D electromagnetic finite element field solver employing quadratic hexahedral elements and quadratic mixed-order one-form basis functions will be described. The solver is based on an object-oriented C++ class library. Test cases demonstrate that frequency errors less than 10 ppm can be achieved using modest workstations, and that the solutions have no contamination from spurious modes. The role of differential geometry and geometrical physics in finite element analysis will also be discussed

  14. Why is a high accuracy needed in dosimetry

    International Nuclear Information System (INIS)

    Lanzl, L.H.

    1976-01-01

    Dose and exposure intercomparisons on a national or international basis have become an important component of quality assurance in the practice of good radiotherapy. A high degree of accuracy of γ and x radiation dosimetry is essential in our international society, where medical information is so readily exchanged and used. The value of accurate dosimetry lies mainly in the avoidance of complications in normal tissue and an optimal degree of tumor control

  15. A High-Throughput, High-Accuracy System-Level Simulation Framework for System on Chips

    Directory of Open Access Journals (Sweden)

    Guanyi Sun

    2011-01-01

    Full Text Available Today's System-on-Chips (SoCs design is extremely challenging because it involves complicated design tradeoffs and heterogeneous design expertise. To explore the large solution space, system architects have to rely on system-level simulators to identify an optimized SoC architecture. In this paper, we propose a system-level simulation framework, System Performance Simulation Implementation Mechanism, or SPSIM. Based on SystemC TLM2.0, the framework consists of an executable SoC model, a simulation tool chain, and a modeling methodology. Compared with the large body of existing research in this area, this work is aimed at delivering a high simulation throughput and, at the same time, guaranteeing a high accuracy on real industrial applications. Integrating the leading TLM techniques, our simulator can attain a simulation speed that is not slower than that of the hardware execution by a factor of 35 on a set of real-world applications. SPSIM incorporates effective timing models, which can achieve a high accuracy after hardware-based calibration. Experimental results on a set of mobile applications proved that the difference between the simulated and measured results of timing performance is within 10%, which in the past can only be attained by cycle-accurate models.

  16. Achieving High Accuracy in Calculations of NMR Parameters

    DEFF Research Database (Denmark)

    Faber, Rasmus

    quantum chemical methods have been developed, the calculation of NMR parameters with quantitative accuracy is far from trivial. In this thesis I address some of the issues that makes accurate calculation of NMR parameters so challenging, with the main focus on SSCCs. High accuracy quantum chemical......, but no programs were available to perform such calculations. As part of this thesis the CFOUR program has therefore been extended to allow the calculation of SSCCs using the CC3 method. CC3 calculations of SSCCs have then been performed for several molecules, including some difficult cases. These results show...... vibrations must be included. The calculation of vibrational corrections to NMR parameters has been reviewed as part of this thesis. A study of the basis set convergence of vibrational corrections to nuclear shielding constants has also been performed. The basis set error in vibrational correction...

  17. High accuracy digital aging monitor based on PLL-VCO circuit

    International Nuclear Information System (INIS)

    Zhang Yuejun; Jiang Zhidi; Wang Pengjun; Zhang Xuelong

    2015-01-01

    As the manufacturing process is scaled down to the nanoscale, the aging phenomenon significantly affects the reliability and lifetime of integrated circuits. Consequently, the precise measurement of digital CMOS aging is a key aspect of nanoscale aging tolerant circuit design. This paper proposes a high accuracy digital aging monitor using phase-locked loop and voltage-controlled oscillator (PLL-VCO) circuit. The proposed monitor eliminates the circuit self-aging effect for the characteristic of PLL, whose frequency has no relationship with circuit aging phenomenon. The PLL-VCO monitor is implemented in TSMC low power 65 nm CMOS technology, and its area occupies 303.28 × 298.94 μm 2 . After accelerating aging tests, the experimental results show that PLL-VCO monitor improves accuracy about high temperature by 2.4% and high voltage by 18.7%. (semiconductor integrated circuits)

  18. A high accuracy land use/cover retrieval system

    Directory of Open Access Journals (Sweden)

    Alaa Hefnawy

    2012-03-01

    Full Text Available The effects of spatial resolution on the accuracy of mapping land use/cover types have received increasing attention as a large number of multi-scale earth observation data become available. Although many methods of semi automated image classification of remotely sensed data have been established for improving the accuracy of land use/cover classification during the past 40 years, most of them were employed in single-resolution image classification, which led to unsatisfactory results. In this paper, we propose a multi-resolution fast adaptive content-based retrieval system of satellite images. Through our proposed system, we apply a Super Resolution technique for the Landsat-TM images to have a high resolution dataset. The human–computer interactive system is based on modified radial basis function for retrieval of satellite database images. We apply the backpropagation supervised artificial neural network classifier for both the multi and single resolution datasets. The results show significant improved land use/cover classification accuracy for the multi-resolution approach compared with those from single-resolution approach.

  19. High Accuracy Piezoelectric Kinemometer; Cinemometro piezoelectrico de alta exactitud (VUAE)

    Energy Technology Data Exchange (ETDEWEB)

    Jimenez Martinez, F. J.; Frutos, J. de; Pastor, C.; Vazquez Rodriguez, M.

    2012-07-01

    We have developed a portable computerized and low consumption, our system is called High Accuracy Piezoelectric Kinemometer measurement, herein VUAE. By the high accuracy obtained by VUAE it make able to use the VUAE to obtain references measurements of system for measuring Speeds in Vehicles. Therefore VUAE could be used how reference equipment to estimate the error of installed kinemometers. The VUAE was created with n (n=2) pairs of ultrasonic transmitter-receiver, herein E-Rult. The transmitters used in the n couples E-Rult generate n ultrasonic barriers and receivers receive the echoes when the vehicle crosses the barriers. Digital processing of the echoes signals let us to obtain acceptable signals. Later, by mean of cross correlation technics is possible make a highly exact estimation of speed of the vehicle. The log of the moments of interception and the distance between each of the n ultrasounds allows for a highly exact estimation of speed of the vehicle. VUAE speed measurements were compared to a speed reference system based on piezoelectric cables. (Author) 11 refs.

  20. High accuracy 3D electromagnetic finite element analysis

    International Nuclear Information System (INIS)

    Nelson, E.M.

    1997-01-01

    A high accuracy 3D electromagnetic finite element field solver employing quadratic hexahedral elements and quadratic mixed-order one-form basis functions will be described. The solver is based on an object-oriented C++ class library. Test cases demonstrate that frequency errors less than 10 ppm can be achieved using modest workstations, and that the solutions have no contamination from spurious modes. The role of differential geometry and geometrical physics in finite element analysis will also be discussed. copyright 1997 American Institute of Physics

  1. Improved patient repositioning accuracy by integrating an additional jaw fixation into a high precision face mask system in stereotactic radiotherapy of the head; Verbesserte lagerungsreproduzierbarkeit eines nichtinvasiven hochpraezisionsmaskensystems in der stereotaktischen Radiotherapie durch eine integrierte kieferfixierung

    Energy Technology Data Exchange (ETDEWEB)

    Lopatta, E.; Liesenfeld, S.M.; Bank, P.; Guenther, R.; Wiezorek, T.; Wendt, T.G. [Klinik fuer Radiologie, Abt. fuer Strahlentherapie, Friedrich-Schiller-Univ. Jena (Germany); Wurm, R. [Campus Charite Mitte, Klinik fuer Strahlentherapie, Berlin (Germany)

    2003-08-01

    Background: For high precision radiotherapy of the neurocranium a precise, reproducible positioning technique is the basic pre-requisite. The aim of this study was to assess the influence of a modification of the commercially available stereotactical BrainLab {sup trademark} -head mask system on accuracy in patient positioning during fractionated radiotherapy. Material and Methods: 29 patients were treated with stereotactic radiotherapy of the head. Immobilization was provided by a two layer thermoplastic mask system (BrainLab trademark). 18 of these patients received an additional custom made fixation either of the upper jaw (OKF) or of the mandibula (UKF). The positioning accuracy was assessed by measurements of the shifting of anatomical landmarks in relation to therigid mask system on biplanar simulator films using a digital imaging system. Before each measurement a fine adjustment of the simulator to an optical ring system was performed. The reference radiographs were done just before CT-planning. During a 2-7 weeks lasting course of radiotherapy displacement measurements in relation to the reference images for all three dimensions (z, y and x) were done once a week. In 29 patients 844 measurements were analyzed. Results: An additional jaw fixation improves the reproducibility of patient positioning significantly in all three spatial dimensions. The standard deviation in lateral direction (x) was 0.6 mm with jaw fixation vs. 0.7 mm without jaw fixation (p < 0.001); in longitudinal direction (z) (measured in 0 radiographs) 0.5 mm vs. 1.3 mm (p < 0.001); in longitudinal direction measured in 90 (orig.) [German] Hintergrund: Eine Grundvoraussetzung fuer die Praezisionsbestrahlung im Bereich des Neurokraniums ist eine genaue, reproduzierbare Lagerungstechnik. Die vorliegende Arbeit untersucht den Einfluss einer Modifikation am kommerziell erhaeltlichen stereotaktischen BrainLab trademark -Kopfmaskensystem auf die Lagerungsgenauigkeit waehrend einer fraktionierten

  2. High-accuracy mass spectrometry for fundamental studies.

    Science.gov (United States)

    Kluge, H-Jürgen

    2010-01-01

    Mass spectrometry for fundamental studies in metrology and atomic, nuclear and particle physics requires extreme sensitivity and efficiency as well as ultimate resolving power and accuracy. An overview will be given on the global status of high-accuracy mass spectrometry for fundamental physics and metrology. Three quite different examples of modern mass spectrometric experiments in physics are presented: (i) the retardation spectrometer KATRIN at the Forschungszentrum Karlsruhe, employing electrostatic filtering in combination with magnetic-adiabatic collimation-the biggest mass spectrometer for determining the smallest mass, i.e. the mass of the electron anti-neutrino, (ii) the Experimental Cooler-Storage Ring at GSI-a mass spectrometer of medium size, relative to other accelerators, for determining medium-heavy masses and (iii) the Penning trap facility, SHIPTRAP, at GSI-the smallest mass spectrometer for determining the heaviest masses, those of super-heavy elements. Finally, a short view into the future will address the GSI project HITRAP at GSI for fundamental studies with highly-charged ions.

  3. Read-only high accuracy volume holographic optical correlator

    Science.gov (United States)

    Zhao, Tian; Li, Jingming; Cao, Liangcai; He, Qingsheng; Jin, Guofan

    2011-10-01

    A read-only volume holographic correlator (VHC) is proposed. After the recording of all of the correlation database pages by angular multiplexing, a stand-alone read-only high accuracy VHC will be separated from the VHC recording facilities which include the high-power laser and the angular multiplexing system. The stand-alone VHC has its own low power readout laser and very compact and simple structure. Since there are two lasers that are employed for recording and readout, respectively, the optical alignment tolerance of the laser illumination on the SLM is very sensitive. The twodimensional angular tolerance is analyzed based on the theoretical model of the volume holographic correlator. The experimental demonstration of the proposed read-only VHC is introduced and discussed.

  4. Amplitude Integrated Electroencephalography Compared With Conventional Video EEG for Neonatal Seizure Detection: A Diagnostic Accuracy Study.

    Science.gov (United States)

    Rakshasbhuvankar, Abhijeet; Rao, Shripada; Palumbo, Linda; Ghosh, Soumya; Nagarajan, Lakshmi

    2017-08-01

    This diagnostic accuracy study compared the accuracy of seizure detection by amplitude-integrated electroencephalography with the criterion standard conventional video EEG in term and near-term infants at risk of seizures. Simultaneous recording of amplitude-integrated EEG (2-channel amplitude-integrated EEG with raw trace) and video EEG was done for 24 hours for each infant. Amplitude-integrated EEG was interpreted by a neonatologist; video EEG was interpreted by a neurologist independently. Thirty-five infants were included in the analysis. In the 7 infants with seizures on video EEG, there were 169 seizure episodes on video EEG, of which only 57 were identified by amplitude-integrated EEG. Amplitude-integrated EEG had a sensitivity of 33.7% for individual seizure detection. Amplitude-integrated EEG had an 86% sensitivity for detection of babies with seizures; however, it was nonspecific, in that 50% of infants with seizures detected by amplitude-integrated EEG did not have true seizures by video EEG. In conclusion, our study suggests that amplitude-integrated EEG is a poor screening tool for neonatal seizures.

  5. An ultrahigh-accuracy Miniature Dew Point Sensor based on an Integrated Photonics Platform

    Science.gov (United States)

    Tao, Jifang; Luo, Yu; Wang, Li; Cai, Hong; Sun, Tao; Song, Junfeng; Liu, Hui; Gu, Yuandong

    2016-07-01

    The dew point is the temperature at which vapour begins to condense out of the gaseous phase. The deterministic relationship between the dew point and humidity is the basis for the industry-standard “chilled-mirror” dew point hygrometers used for highly accurate humidity measurements, which are essential for a broad range of industrial and metrological applications. However, these instruments have several limitations, such as high cost, large size and slow response. In this report, we demonstrate a compact, integrated photonic dew point sensor (DPS) that features high accuracy, a small footprint, and fast response. The fundamental component of this DPS is a partially exposed photonic micro-ring resonator, which serves two functions simultaneously: 1) sensing the condensed water droplets via evanescent fields and 2) functioning as a highly accurate, in situ temperature sensor based on the thermo-optic effect (TOE). This device virtually eliminates most of the temperature-related errors that affect conventional “chilled-mirror” hygrometers. Moreover, this DPS outperforms conventional “chilled-mirror” hygrometers with respect to size, cost and response time, paving the way for on-chip dew point detection and extension to applications for which the conventional technology is unsuitable because of size, cost, and other constraints.

  6. Epistemic and aleatory uncertainties in integrated deterministic and probabilistic safety assessment: Tradeoff between accuracy and accident simulations

    International Nuclear Information System (INIS)

    Karanki, D.R.; Rahman, S.; Dang, V.N.; Zerkak, O.

    2017-01-01

    The coupling of plant simulation models and stochastic models representing failure events in Dynamic Event Trees (DET) is a framework used to model the dynamic interactions among physical processes, equipment failures, and operator responses. The integration of physical and stochastic models may additionally enhance the treatment of uncertainties. Probabilistic Safety Assessments as currently implemented propagate the (epistemic) uncertainties in failure probabilities, rates, and frequencies; while the uncertainties in the physical model (parameters) are not propagated. The coupling of deterministic (physical) and probabilistic models in integrated simulations such as DET allows both types of uncertainties to be considered. However, integrated accident simulations with epistemic uncertainties will challenge even today's high performance computing infrastructure, especially for simulations of inherently complex nuclear or chemical plants. Conversely, intentionally limiting computations for practical reasons would compromise accuracy of results. This work investigates how to tradeoff accuracy and computations to quantify risk in light of both uncertainties and accident dynamics. A simple depleting tank problem that can be solved analytically is considered to examine the adequacy of a discrete DET approach. The results show that optimal allocation of computational resources between epistemic and aleatory calculations by means of convergence studies ensures accuracy within a limited budget. - Highlights: • Accident simulations considering uncertainties require intensive computations. • Tradeoff between accuracy and accident simulations is a challenge. • Optimal allocation between epistemic & aleatory computations ensures the tradeoff. • Online convergence gives an early indication of computational requirements. • Uncertainty propagation in DDET is examined on a tank problem solved analytically.

  7. Synchrotron accelerator technology for proton beam therapy with high accuracy

    International Nuclear Information System (INIS)

    Hiramoto, Kazuo

    2009-01-01

    Proton beam therapy was applied at the beginning to head and neck cancers, but it is now extended to prostate, lung and liver cancers. Thus the need for a pencil beam scanning method is increasing. With this method radiation dose concentration property of the proton beam will be further intensified. Hitachi group has supplied a pencil beam scanning therapy system as the first one for M. D. Anderson Hospital in United States, and it has been operational since May 2008. Hitachi group has been developing proton therapy system to correspond high-accuracy proton therapy to concentrate the dose in the diseased part which is located with various depths, and which sometimes has complicated shape. The author described here on the synchrotron accelerator technology that is an important element for constituting the proton therapy system. (K.Y.)

  8. High accuracy mantle convection simulation through modern numerical methods

    KAUST Repository

    Kronbichler, Martin

    2012-08-21

    Numerical simulation of the processes in the Earth\\'s mantle is a key piece in understanding its dynamics, composition, history and interaction with the lithosphere and the Earth\\'s core. However, doing so presents many practical difficulties related to the numerical methods that can accurately represent these processes at relevant scales. This paper presents an overview of the state of the art in algorithms for high-Rayleigh number flows such as those in the Earth\\'s mantle, and discusses their implementation in the Open Source code Aspect (Advanced Solver for Problems in Earth\\'s ConvecTion). Specifically, we show how an interconnected set of methods for adaptive mesh refinement (AMR), higher order spatial and temporal discretizations, advection stabilization and efficient linear solvers can provide high accuracy at a numerical cost unachievable with traditional methods, and how these methods can be designed in a way so that they scale to large numbers of processors on compute clusters. Aspect relies on the numerical software packages deal.II and Trilinos, enabling us to focus on high level code and keeping our implementation compact. We present results from validation tests using widely used benchmarks for our code, as well as scaling results from parallel runs. © 2012 The Authors Geophysical Journal International © 2012 RAS.

  9. Gene masking - a technique to improve accuracy for cancer classification with high dimensionality in microarray data.

    Science.gov (United States)

    Saini, Harsh; Lal, Sunil Pranit; Naidu, Vimal Vikash; Pickering, Vincel Wince; Singh, Gurmeet; Tsunoda, Tatsuhiko; Sharma, Alok

    2016-12-05

    High dimensional feature space generally degrades classification in several applications. In this paper, we propose a strategy called gene masking, in which non-contributing dimensions are heuristically removed from the data to improve classification accuracy. Gene masking is implemented via a binary encoded genetic algorithm that can be integrated seamlessly with classifiers during the training phase of classification to perform feature selection. It can also be used to discriminate between features that contribute most to the classification, thereby, allowing researchers to isolate features that may have special significance. This technique was applied on publicly available datasets whereby it substantially reduced the number of features used for classification while maintaining high accuracies. The proposed technique can be extremely useful in feature selection as it heuristically removes non-contributing features to improve the performance of classifiers.

  10. High accuracy magnetic field mapping of the LEP spectrometer magnet

    CERN Document Server

    Roncarolo, F

    2000-01-01

    The Large Electron Positron accelerator (LEP) is a storage ring which has been operated since 1989 at the European Laboratory for Particle Physics (CERN), located in the Geneva area. It is intended to experimentally verify the Standard Model theory and in particular to detect with high accuracy the mass of the electro-weak force bosons. Electrons and positrons are accelerated inside the LEP ring in opposite directions and forced to collide at four locations, once they reach an energy high enough for the experimental purposes. During head-to-head collisions the leptons loose all their energy and a huge amount of energy is concentrated in a small region. In this condition the energy is quickly converted in other particles which tend to go away from the interaction point. The higher the energy of the leptons before the collisions, the higher the mass of the particles that can escape. At LEP four large experimental detectors are accommodated. All detectors are multi purpose detectors covering a solid angle of alm...

  11. Accuracy assessment of high-rate GPS measurements for seismology

    Science.gov (United States)

    Elosegui, P.; Davis, J. L.; Ekström, G.

    2007-12-01

    Analysis of GPS measurements with a controlled laboratory system, built to simulate the ground motions caused by tectonic earthquakes and other transient geophysical signals such as glacial earthquakes, enables us to assess the technique of high-rate GPS. The root-mean-square (rms) position error of this system when undergoing realistic simulated seismic motions is 0.05~mm, with maximum position errors of 0.1~mm, thus providing "ground truth" GPS displacements. We have acquired an extensive set of high-rate GPS measurements while inducing seismic motions on a GPS antenna mounted on this system with a temporal spectrum similar to real seismic events. We found that, for a particular 15-min-long test event, the rms error of the 1-Hz GPS position estimates was 2.5~mm, with maximum position errors of 10~mm, and the error spectrum of the GPS estimates was approximately flicker noise. These results may however represent a best-case scenario since they were obtained over a short (~10~m) baseline, thereby greatly mitigating baseline-dependent errors, and when the number and distribution of satellites on the sky was good. For example, we have determined that the rms error can increase by a factor of 2--3 as the GPS constellation changes throughout the day, with an average value of 3.5~mm for eight identical, hourly-spaced, consecutive test events. The rms error also increases with increasing baseline, as one would expect, with an average rms error for a ~1400~km baseline of 9~mm. We will present an assessment of the accuracy of high-rate GPS based on these measurements, discuss the implications of this study for seismology, and describe new applications in glaciology.

  12. Accuracy assessment of cadastral maps using high resolution aerial photos

    Directory of Open Access Journals (Sweden)

    Alwan Imzahim

    2018-01-01

    Full Text Available A cadastral map is a map that shows the boundaries and ownership of land parcels. Some cadastral maps show additional details, such as survey district names, unique identifying numbers for parcels, certificate of title numbers, positions of existing structures, section or lot numbers and their respective areas, adjoining and adjacent street names, selected boundary dimensions and references to prior maps. In Iraq / Baghdad Governorate, the main problem is that the cadastral maps are georeferenced to a local geodetic datum known as Clark 1880 while the widely used reference system for navigation purpose (GPS and GNSS and uses Word Geodetic System 1984 (WGS84 as a base reference datum. The objective of this paper is to produce a cadastral map with scale 1:500 (metric scale by using aerial photographs 2009 with high ground spatial resolution 10 cm reference WGS84 system. The accuracy assessment for the cadastral maps updating approach to urban large scale cadastral maps (1:500-1:1000 was ± 0.115 meters; which complies with the American Social for Photogrammetry and Remote Sensing Standards (ASPRS.

  13. Modified sine bar device measures small angles with high accuracy

    Science.gov (United States)

    Thekaekara, M.

    1968-01-01

    Modified sine bar device measures small angles with enough accuracy to calibrate precision optical autocollimators. The sine bar is a massive bar of steel supported by two cylindrical rods at one end and one at the other.

  14. Talk about high integrity container

    International Nuclear Information System (INIS)

    Luo Shanggeng

    2009-01-01

    The high integrity container (HIC) has been paid great attention to recently in China. The reason and the comparison of advantages and disadvantages are described in this article. The characteristics and fabrications of some foreign HIC and their test procedures have been introduced. Finally, some opinion and discussion related to develop HIC are put forward, too. (author)

  15. Integrated three-dimensional digital assessment of accuracy of anterior tooth movement using clear aligners

    OpenAIRE

    Zhang, Xiao-Juan; He, Li; Guo, Hong-Ming; Tian, Jie; Bai, Yu-Xing; Li, Song

    2015-01-01

    Objective To assess the accuracy of anterior tooth movement using clear aligners in integrated three-dimensional digital models. Methods Cone-beam computed tomography was performed before and after treatment with clear aligners in 32 patients. Plaster casts were laser-scanned for virtual setup and aligner fabrication. Differences in predicted and achieved root and crown positions of anterior teeth were compared on superimposed maxillofacial digital images and virtual models and analyzed by St...

  16. Measurement system with high accuracy for laser beam quality.

    Science.gov (United States)

    Ke, Yi; Zeng, Ciling; Xie, Peiyuan; Jiang, Qingshan; Liang, Ke; Yang, Zhenyu; Zhao, Ming

    2015-05-20

    Presently, most of the laser beam quality measurement system collimates the optical path manually with low efficiency and low repeatability. To solve these problems, this paper proposed a new collimated method to improve the reliability and accuracy of the measurement results. The system accuracy controlled the position of the mirror to change laser beam propagation direction, which can realize the beam perpendicularly incident to the photosurface of camera. The experiment results show that the proposed system has good repeatability and the measuring deviation of M2 factor is less than 0.6%.

  17. High-accuracy Subdaily ERPs from the IGS

    Science.gov (United States)

    Ray, J. R.; Griffiths, J.

    2012-04-01

    Since November 2000 the International GNSS Service (IGS) has published Ultra-rapid (IGU) products for near real-time (RT) and true real-time applications. They include satellite orbits and clocks, as well as Earth rotation parameters (ERPs) for a sliding 48-hr period. The first day of each update is based on the most recent GPS and GLONASS observational data from the IGS hourly tracking network. At the time of release, these observed products have an initial latency of 3 hr. The second day of each update consists of predictions. So the predictions between about 3 and 9 hr into the second half are relevant for true RT uses. Originally updated twice daily, the IGU products since April 2004 have been issued every 6 hr, at 3, 9, 15, and 21 UTC. Up to seven Analysis Centers (ACs) contribute to the IGU combinations. Two sets of ERPs are published with each IGU update, observed values at the middle epoch of the first half and predicted values at the middle epoch of the second half. The latency of the near RT ERPs is 15 hr while the predicted ERPs, based on projections of each AC's most recent determinations, are issued 9 hr ahead of their reference epoch. While IGU ERPs are issued every 6 hr, each set represents an integrated estimate over the surrounding 24 hr. So successive values are temporally correlated with about 75% of the data being common; this fact should be taken into account in user assimilations. To evaluate the accuracy of these near RT and predicted ERPs, they have been compared to the IGS Final ERPs, available about 11 to 17 d after data collection. The IGU products improved dramatically in the earlier years but since about 2008.0 the performance has been stable and excellent. During the last three years, RMS differences for the observed IGU ERPs have been about 0.036 mas and 0.0101 ms for each polar motion component and LOD respectively. (The internal precision of the reference IGS ERPs over the same period is about 0.016 mas for polar motion and 0

  18. Accuracy assessment of topographic mapping using UAV image integrated with satellite images

    International Nuclear Information System (INIS)

    Azmi, S M; Ahmad, Baharin; Ahmad, Anuar

    2014-01-01

    Unmanned Aerial Vehicle or UAV is extensively applied in various fields such as military applications, archaeology, agriculture and scientific research. This study focuses on topographic mapping and map updating. UAV is one of the alternative ways to ease the process of acquiring data with lower operating costs, low manufacturing and operational costs, plus it is easy to operate. Furthermore, UAV images will be integrated with QuickBird images that are used as base maps. The objective of this study is to make accuracy assessment and comparison between topographic mapping using UAV images integrated with aerial photograph and satellite image. The main purpose of using UAV image is as a replacement for cloud covered area which normally exists in aerial photograph and satellite image, and for updating topographic map. Meanwhile, spatial resolution, pixel size, scale, geometric accuracy and correction, image quality and information contents are important requirements needed for the generation of topographic map using these kinds of data. In this study, ground control points (GCPs) and check points (CPs) were established using real time kinematic Global Positioning System (RTK-GPS) technique. There are two types of analysis that are carried out in this study which are quantitative and qualitative assessments. Quantitative assessment is carried out by calculating root mean square error (RMSE). The outputs of this study include topographic map and orthophoto. From this study, the accuracy of UAV image is ± 0.460 m. As conclusion, UAV image has the potential to be used for updating of topographic maps

  19. Evaluating perceptual integration: uniting response-time- and accuracy-based methodologies.

    Science.gov (United States)

    Eidels, Ami; Townsend, James T; Hughes, Howard C; Perry, Lacey A

    2015-02-01

    This investigation brings together a response-time system identification methodology (e.g., Townsend & Wenger Psychonomic Bulletin & Review 11, 391-418, 2004a) and an accuracy methodology, intended to assess models of integration across stimulus dimensions (features, modalities, etc.) that were proposed by Shaw and colleagues (e.g., Mulligan & Shaw Perception & Psychophysics 28, 471-478, 1980). The goal was to theoretically examine these separate strategies and to apply them conjointly to the same set of participants. The empirical phases were carried out within an extension of an established experimental design called the double factorial paradigm (e.g., Townsend & Nozawa Journal of Mathematical Psychology 39, 321-359, 1995). That paradigm, based on response times, permits assessments of architecture (parallel vs. serial processing), stopping rule (exhaustive vs. minimum time), and workload capacity, all within the same blocks of trials. The paradigm introduced by Shaw and colleagues uses a statistic formally analogous to that of the double factorial paradigm, but based on accuracy rather than response times. We demonstrate that the accuracy measure cannot discriminate between parallel and serial processing. Nonetheless, the class of models supported by the accuracy data possesses a suitable interpretation within the same set of models supported by the response-time data. The supported model, consistent across individuals, is parallel and has limited capacity, with the participants employing the appropriate stopping rule for the experimental setting.

  20. Implementation of High Time Delay Accuracy of Ultrasonic Phased Array Based on Interpolation CIC Filter.

    Science.gov (United States)

    Liu, Peilu; Li, Xinghua; Li, Haopeng; Su, Zhikun; Zhang, Hongxu

    2017-10-12

    In order to improve the accuracy of ultrasonic phased array focusing time delay, analyzing the original interpolation Cascade-Integrator-Comb (CIC) filter, an 8× interpolation CIC filter parallel algorithm was proposed, so that interpolation and multichannel decomposition can simultaneously process. Moreover, we summarized the general formula of arbitrary multiple interpolation CIC filter parallel algorithm and established an ultrasonic phased array focusing time delay system based on 8× interpolation CIC filter parallel algorithm. Improving the algorithmic structure, 12.5% of addition and 29.2% of multiplication was reduced, meanwhile the speed of computation is still very fast. Considering the existing problems of the CIC filter, we compensated the CIC filter; the compensated CIC filter's pass band is flatter, the transition band becomes steep, and the stop band attenuation increases. Finally, we verified the feasibility of this algorithm on Field Programming Gate Array (FPGA). In the case of system clock is 125 MHz, after 8× interpolation filtering and decomposition, time delay accuracy of the defect echo becomes 1 ns. Simulation and experimental results both show that the algorithm we proposed has strong feasibility. Because of the fast calculation, small computational amount and high resolution, this algorithm is especially suitable for applications with high time delay accuracy and fast detection.

  1. Implementation of High Time Delay Accuracy of Ultrasonic Phased Array Based on Interpolation CIC Filter

    Directory of Open Access Journals (Sweden)

    Peilu Liu

    2017-10-01

    Full Text Available In order to improve the accuracy of ultrasonic phased array focusing time delay, analyzing the original interpolation Cascade-Integrator-Comb (CIC filter, an 8× interpolation CIC filter parallel algorithm was proposed, so that interpolation and multichannel decomposition can simultaneously process. Moreover, we summarized the general formula of arbitrary multiple interpolation CIC filter parallel algorithm and established an ultrasonic phased array focusing time delay system based on 8× interpolation CIC filter parallel algorithm. Improving the algorithmic structure, 12.5% of addition and 29.2% of multiplication was reduced, meanwhile the speed of computation is still very fast. Considering the existing problems of the CIC filter, we compensated the CIC filter; the compensated CIC filter’s pass band is flatter, the transition band becomes steep, and the stop band attenuation increases. Finally, we verified the feasibility of this algorithm on Field Programming Gate Array (FPGA. In the case of system clock is 125 MHz, after 8× interpolation filtering and decomposition, time delay accuracy of the defect echo becomes 1 ns. Simulation and experimental results both show that the algorithm we proposed has strong feasibility. Because of the fast calculation, small computational amount and high resolution, this algorithm is especially suitable for applications with high time delay accuracy and fast detection.

  2. Diagnostic accuracy of high-definition CT coronary angiography in high-risk patients

    International Nuclear Information System (INIS)

    Iyengar, S.S.; Morgan-Hughes, G.; Ukoumunne, O.; Clayton, B.; Davies, E.J.; Nikolaou, V.; Hyde, C.J.; Shore, A.C.; Roobottom, C.A.

    2016-01-01

    Aim: To assess the diagnostic accuracy of computed tomography coronary angiography (CTCA) using a combination of high-definition CT (HD-CTCA) and high level of reader experience, with invasive coronary angiography (ICA) as the reference standard, in high-risk patients for the investigation of coronary artery disease (CAD). Materials and methods: Three hundred high-risk patients underwent HD-CTCA and ICA. Independent experts evaluated the images for the presence of significant CAD, defined primarily as the presence of moderate (≥50%) stenosis and secondarily as the presence of severe (≥70%) stenosis in at least one coronary segment, in a blinded fashion. HD-CTCA was compared to ICA as the reference standard. Results: No patients were excluded. Two hundred and six patients (69%) had moderate and 178 (59%) had severe stenosis in at least one vessel at ICA. The sensitivity, specificity, positive predictive value, and negative predictive value were 97.1%, 97.9%, 99% and 93.9% for moderate stenosis, and 98.9%, 93.4%, 95.7% and 98.3%, for severe stenosis, on a per-patient basis. Conclusion: The combination of HD-CTCA and experienced readers applied to a high-risk population, results in high diagnostic accuracy comparable to ICA. Modern generation CT systems in experienced hands might be considered for an expanded role. - Highlights: • Diagnostic accuracy of High-Definition CT Angiography (HD-CTCA) has been assessed. • Invasive Coronary angiography (ICA) is the reference standard. • Diagnostic accuracy of HD-CTCA is comparable to ICA. • Diagnostic accuracy is not affected by coronary calcium or stents. • HD-CTCA provides a non-invasive alternative in high-risk patients.

  3. Effects of Dissolving Solutions on the Accuracy of an Electronic Apex Locator-Integrated Endodontic Handpiece

    Directory of Open Access Journals (Sweden)

    Yakup Ustun

    2013-01-01

    Full Text Available The effects of three dissolving agents on the accuracy of an electronic apex locator- (EAL- integrated endodontic handpiece during retreatment procedures were evaluated. The true lengths (TLs of 56 extracted incisor teeth were determined visually. Twenty teeth were filled with gutta-percha and a resin-based sealer (group A, 20 with gutta-percha and a zinc oxide/eugenol-based sealer (group B, and 16 roots were used as the control group (group C. All roots were prepared to TL. Guttasolv, Resosolv, and Endosolv E were used as the dissolving solutions. Two evaluations of the handpiece were performed: the apical accuracy during the auto reverse function (ARL and the apex locator function (EL alone. The ARL function of the handpiece gave acceptable results. There were significant differences between the EL mode measurements and the TL (P<0.05. In these comparisons, Tri Auto ZX EL mode measurements were significantly shorter than those of the TL.

  4. High-accuracy user identification using EEG biometrics.

    Science.gov (United States)

    Koike-Akino, Toshiaki; Mahajan, Ruhi; Marks, Tim K; Ye Wang; Watanabe, Shinji; Tuzel, Oncel; Orlik, Philip

    2016-08-01

    We analyze brain waves acquired through a consumer-grade EEG device to investigate its capabilities for user identification and authentication. First, we show the statistical significance of the P300 component in event-related potential (ERP) data from 14-channel EEGs across 25 subjects. We then apply a variety of machine learning techniques, comparing the user identification performance of various different combinations of a dimensionality reduction technique followed by a classification algorithm. Experimental results show that an identification accuracy of 72% can be achieved using only a single 800 ms ERP epoch. In addition, we demonstrate that the user identification accuracy can be significantly improved to more than 96.7% by joint classification of multiple epochs.

  5. High Accuracy Nonlinear Control and Estimation for Machine Tool Systems

    DEFF Research Database (Denmark)

    Papageorgiou, Dimitrios

    Component mass production has been the backbone of industry since the second industrial revolution, and machine tools are producing parts of widely varying size and design complexity. The ever-increasing level of automation in modern manufacturing processes necessitates the use of more...... sophisticated machine tool systems that are adaptable to different workspace conditions, while at the same time being able to maintain very narrow workpiece tolerances. The main topic of this thesis is to suggest control methods that can maintain required manufacturing tolerances, despite moderate wear and tear....... The purpose is to ensure that full accuracy is maintained between service intervals and to advice when overhaul is needed. The thesis argues that quality of manufactured components is directly related to the positioning accuracy of the machine tool axes, and it shows which low level control architectures...

  6. Methodology for GPS Synchronization Evaluation with High Accuracy

    OpenAIRE

    Li Zan; Braun Torsten; Dimitrova Desislava

    2015-01-01

    Clock synchronization in the order of nanoseconds is one of the critical factors for time based localization. Currently used time synchronization methods are developed for the more relaxed needs of network operation. Their usability for positioning should be carefully evaluated. In this paper we are particularly interested in GPS based time synchronization. To judge its usability for localization we need a method that can evaluate the achieved time synchronization with nanosecond accuracy. Ou...

  7. Methodology for GPS Synchronization Evaluation with High Accuracy

    OpenAIRE

    Li, Zan; Braun, Torsten; Dimitrova, Desislava Cvetanova

    2015-01-01

    Clock synchronization in the order of nanoseconds is one of the critical factors for time-based localization. Currently used time synchronization methods are developed for the more relaxed needs of network operation. Their usability for positioning should be carefully evaluated. In this paper, we are particularly interested in GPS-based time synchronization. To judge its usability for localization we need a method that can evaluate the achieved time synchronization with nanosecond accuracy. O...

  8. Image accuracy and representational enhancement through low-level, multi-sensor integration techniques

    International Nuclear Information System (INIS)

    Baker, J.E.

    1993-05-01

    Multi-Sensor Integration (MSI) is the combining of data and information from more than one source in order to generate a more reliable and consistent representation of the environment. The need for MSI derives largely from basic ambiguities inherent in our current sensor imaging technologies. These ambiguities exist as long as the mapping from reality to image is not 1-to-1. That is, if different 44 realities'' lead to identical images, a single image cannot reveal the particular reality which was the truth. MSI techniques can be divided into three categories based on the relative information content of the original images with that of the desired representation: (1) ''detail enhancement,'' wherein the relative information content of the original images is less rich than the desired representation; (2) ''data enhancement,'' wherein the MSI techniques axe concerned with improving the accuracy of the data rather than either increasing or decreasing the level of detail; and (3) ''conceptual enhancement,'' wherein the image contains more detail than is desired, making it difficult to easily recognize objects of interest. In conceptual enhancement one must group pixels corresponding to the same conceptual object and thereby reduce the level of extraneous detail. This research focuses on data and conceptual enhancement algorithms. To be useful in many real-world applications, e.g., autonomous or teleoperated robotics, real-time feedback is critical. But, many MSI/image processing algorithms require significant processing time. This is especially true of feature extraction, object isolation, and object recognition algorithms due to their typical reliance on global or large neighborhood information. This research attempts to exploit the speed currently available in state-of-the-art digitizers and highly parallel processing systems by developing MSI algorithms based on pixel rather than global-level features

  9. Thermal effects on human performance in office environment measured by integrating task speed and accuracy

    DEFF Research Database (Denmark)

    Lan, Li; Wargocki, Pawel; Lian, Zhiwei

    2014-01-01

    We have proposed a method in which the speed and accuracy can be integrated into one metric of human performance. This was achieved by designing a performance task in which the subjects receive feedback on their performance by informing them whether they have committed errors, and if did, they can......, 12 subjects performed tasks under two thermal conditions (neutral & warm) repeatedly. The tasks were presented with and without feedback on errors committed, as outlined above. The results indicate that there was a greater decrease in task performance due to thermal discomfort when feedback was given......, compared to the performance of tasks presented without feedback....

  10. Research on Horizontal Accuracy Method of High Spatial Resolution Remotely Sensed Orthophoto Image

    Science.gov (United States)

    Xu, Y. M.; Zhang, J. X.; Yu, F.; Dong, S.

    2018-04-01

    At present, in the inspection and acceptance of high spatial resolution remotly sensed orthophoto image, the horizontal accuracy detection is testing and evaluating the accuracy of images, which mostly based on a set of testing points with the same accuracy and reliability. However, it is difficult to get a set of testing points with the same accuracy and reliability in the areas where the field measurement is difficult and the reference data with high accuracy is not enough. So it is difficult to test and evaluate the horizontal accuracy of the orthophoto image. The uncertainty of the horizontal accuracy has become a bottleneck for the application of satellite borne high-resolution remote sensing image and the scope of service expansion. Therefore, this paper proposes a new method to test the horizontal accuracy of orthophoto image. This method using the testing points with different accuracy and reliability. These points' source is high accuracy reference data and field measurement. The new method solves the horizontal accuracy detection of the orthophoto image in the difficult areas and provides the basis for providing reliable orthophoto images to the users.

  11. Innovative Fiber-Optic Gyroscopes (FOGs) for High Accuracy Space Applications, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — NASA's future science and exploratory missions will require much lighter, smaller, and longer life rate sensors that can provide high accuracy navigational...

  12. High Accuracy Positioning using Jet Thrusters for Quadcopter

    Directory of Open Access Journals (Sweden)

    Pi ChenHuan

    2018-01-01

    Full Text Available A quadcopter is equipped with four additional jet thrusters on its horizontal plane and vertical to each other in order to improve the maneuverability and positioning accuracy of quadcopter. A dynamic model of the quadcopter with jet thrusters is derived and two controllers are implemented in simulation, one is a dual loop state feedback controller for pose control and another is an auxiliary jet thruster controller for accurate positioning. Step response simulations showed that the jet thruster can control the quadcopter with less overshoot compared to the conventional one. Over 10s loiter simulation with disturbance, the quadcopter with jet thruster decrease 85% of RMS error of horizontal disturbance compared to a conventional quadcopter with only a dual loop state feedback controller. The jet thruster controller shows the possibility for further accurate in the field of quadcopter positioning.

  13. High-accuracy contouring using projection moiré

    Science.gov (United States)

    Sciammarella, Cesar A.; Lamberti, Luciano; Sciammarella, Federico M.

    2005-09-01

    Shadow and projection moiré are the oldest forms of moiré to be used in actual technical applications. In spite of this fact and the extensive number of papers that have been published on this topic, the use of shadow moiré as an accurate tool that can compete with alternative devices poses very many problems that go to the very essence of the mathematical models used to obtain contour information from fringe pattern data. In this paper some recent developments on the projection moiré method are presented. Comparisons between the results obtained with the projection method and the results obtained by mechanical devices that operate with contact probes are presented. These results show that the use of projection moiré makes it possible to achieve the same accuracy that current mechanical touch probe devices can provide.

  14. High-integrity databases for helicopter operations

    Science.gov (United States)

    Pschierer, Christian; Schiefele, Jens; Lüthy, Juerg

    2009-05-01

    Helicopter Emergency Medical Service missions (HEMS) impose a high workload on pilots due to short preparation time, operations in low level flight, and landings in unknown areas. The research project PILAS, a cooperation between Eurocopter, Diehl Avionics, DLR, EADS, Euro Telematik, ESG, Jeppesen, the Universities of Darmstadt and Munich, and funded by the German government, approached this problem by researching a pilot assistance system which supports the pilots during all phases of flight. The databases required for the specified helicopter missions include different types of topological and cultural data for graphical display on the SVS system, AMDB data for operations at airports and helipads, and navigation data for IFR segments. The most critical databases for the PILAS system however are highly accurate terrain and obstacle data. While RTCA DO-276 specifies high accuracies and integrities only for the areas around airports, HEMS helicopters typically operate outside of these controlled areas and thus require highly reliable terrain and obstacle data for their designated response areas. This data has been generated by a LIDAR scan of the specified test region. Obstacles have been extracted into a vector format. This paper includes a short overview of the complete PILAS system and then focus on the generation of the required high quality databases.

  15. Integrated plasma control for high performance tokamaks

    International Nuclear Information System (INIS)

    Humphreys, D.A.; Deranian, R.D.; Ferron, J.R.; Johnson, R.D.; LaHaye, R.J.; Leuer, J.A.; Penaflor, B.G.; Walker, M.L.; Welander, A.S.; Jayakumar, R.J.; Makowski, M.A.; Khayrutdinov, R.R.

    2005-01-01

    Sustaining high performance in a tokamak requires controlling many equilibrium shape and profile characteristics simultaneously with high accuracy and reliability, while suppressing a variety of MHD instabilities. Integrated plasma control, the process of designing high-performance tokamak controllers based on validated system response models and confirming their performance in detailed simulations, provides a systematic method for achieving and ensuring good control performance. For present-day devices, this approach can greatly reduce the need for machine time traditionally dedicated to control optimization, and can allow determination of high-reliability controllers prior to ever producing the target equilibrium experimentally. A full set of tools needed for this approach has recently been completed and applied to present-day devices including DIII-D, NSTX and MAST. This approach has proven essential in the design of several next-generation devices including KSTAR, EAST, JT-60SC, and ITER. We describe the method, results of design and simulation tool development, and recent research producing novel approaches to equilibrium and MHD control in DIII-D. (author)

  16. Broadband EIT borehole measurements with high phase accuracy using numerical corrections of electromagnetic coupling effects

    International Nuclear Information System (INIS)

    Zhao, Y; Zimmermann, E; Wolters, B; Van Waasen, S; Huisman, J A; Treichel, A; Kemna, A

    2013-01-01

    Electrical impedance tomography (EIT) is gaining importance in the field of geophysics and there is increasing interest for accurate borehole EIT measurements in a broad frequency range (mHz to kHz) in order to study subsurface properties. To characterize weakly polarizable soils and sediments with EIT, high phase accuracy is required. Typically, long electrode cables are used for borehole measurements. However, this may lead to undesired electromagnetic coupling effects associated with the inductive coupling between the double wire pairs for current injection and potential measurement and the capacitive coupling between the electrically conductive shield of the cable and the electrically conductive environment surrounding the electrode cables. Depending on the electrical properties of the subsurface and the measured transfer impedances, both coupling effects can cause large phase errors that have typically limited the frequency bandwidth of field EIT measurements to the mHz to Hz range. The aim of this paper is to develop numerical corrections for these phase errors. To this end, the inductive coupling effect was modeled using electronic circuit models, and the capacitive coupling effect was modeled by integrating discrete capacitances in the electrical forward model describing the EIT measurement process. The correction methods were successfully verified with measurements under controlled conditions in a water-filled rain barrel, where a high phase accuracy of 0.8 mrad in the frequency range up to 10 kHz was achieved. The corrections were also applied to field EIT measurements made using a 25 m long EIT borehole chain with eight electrodes and an electrode separation of 1 m. The results of a 1D inversion of these measurements showed that the correction methods increased the measurement accuracy considerably. It was concluded that the proposed correction methods enlarge the bandwidth of the field EIT measurement system, and that accurate EIT measurements can now

  17. Accuracy optimization of high-speed AFM measurements using Design of Experiments

    DEFF Research Database (Denmark)

    Tosello, Guido; Marinello, F.; Hansen, Hans Nørgaard

    2010-01-01

    Atomic Force Microscopy (AFM) is being increasingly employed in industrial micro/nano manufacturing applications and integrated into production lines. In order to achieve reliable process and product control at high measuring speed, instrument optimization is needed. Quantitative AFM measurement...... results are influenced by a number of scan settings parameters, defining topography sampling and measurement time: resolution (number of profiles and points per profile), scan range and direction, scanning force and speed. Such parameters are influencing lateral and vertical accuracy and, eventually......, the estimated dimensions of measured features. The definition of scan settings is based on a comprehensive optimization that targets maximization of information from collected data and minimization of measurement uncertainty and scan time. The Design of Experiments (DOE) technique is proposed and applied...

  18. High Integrity Can Design Interfaces

    International Nuclear Information System (INIS)

    Shaber, E.L.

    1998-01-01

    The National Spent Nuclear Fuel Program is chartered with facilitating the disposition of DOE-owned spent nuclear fuel to allow disposal at a geologic repository. This is done through coordination with the repository program and by assisting DOE Site owners of SNF with needed information, standardized requirements, packaging approaches, etc. The High Integrity Can (HIC) will be manufactured to provide a substitute or barrier enhancement for normal fuel geometry and cladding. The can would be nested inside the DOE standardized canister which is designed to interface with the repository waste package. The HIC approach may provide the following benefits over typical canning approaches for DOE SNF. (a) It allows ready calculation and management of criticality issues for miscellaneous. (b) It segments and further isolates damaged or otherwise problem materials from normal SNF in the repository package. (c) It provides a very long term corrosion barrier. (d) It provides an extra internal pressure barrier for particulates, gaseous fission products, hydrogen, and water vapor. (e) It delays any potential release of fission products to the repository environment. (f) It maintains an additional level of fuel geometry control during design basis accidents, rock-fall, and seismic events. (g) When seal welded, it could provide the additional containment required for shipments involving plutonium content in excess of 20 Ci. (10 CFR 71.63.b) if integrated with an appropriate cask design. Long term corrosion protection is central to the HIC concept. The material selected for the HIC (Hastelloy C-22) has undergone extensive testing for repository service. The most severe theoretical interactions between iron, repository water containing chlorides and other repository construction materials have been tested. These expected chemical species have not been shown capable of corroding the selected HIC material. Therefore, the HIC should provide a significant barrier to DOE SNF dispersal

  19. Integrated three-dimensional digital assessment of accuracy of anterior tooth movement using clear aligners.

    Science.gov (United States)

    Zhang, Xiao-Juan; He, Li; Guo, Hong-Ming; Tian, Jie; Bai, Yu-Xing; Li, Song

    2015-11-01

    To assess the accuracy of anterior tooth movement using clear aligners in integrated three-dimensional digital models. Cone-beam computed tomography was performed before and after treatment with clear aligners in 32 patients. Plaster casts were laser-scanned for virtual setup and aligner fabrication. Differences in predicted and achieved root and crown positions of anterior teeth were compared on superimposed maxillofacial digital images and virtual models and analyzed by Student's t-test. The mean discrepancies in maxillary and mandibular crown positions were 0.376 ± 0.041 mm and 0.398 ± 0.037 mm, respectively. Maxillary and mandibular root positions differed by 2.062 ± 0.128 mm and 1.941 ± 0.154 mm, respectively. Crowns but not roots of anterior teeth can be moved to designated positions using clear aligners, because these appliances cause tooth movement by tilting motion.

  20. Compact, High Accuracy CO2 Monitor, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — This Small Business Innovative Research Phase I proposal seeks to develop a low cost, robust, highly precise and accurate CO2 monitoring system. This system will...

  1. Compact, High Accuracy CO2 Monitor, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — This Small Business Innovative Research Phase II proposal seeks to develop a low cost, robust, highly precise and accurate CO2 monitoring system. This system will...

  2. 45 CFR 61.15 - How to dispute the accuracy of Healthcare Integrity and Protection Data Bank information.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false How to dispute the accuracy of Healthcare Integrity and Protection Data Bank information. 61.15 Section 61.15 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION HEALTHCARE INTEGRITY AND PROTECTION DATA BANK FOR FINAL ADVERSE...

  3. An output amplitude configurable wideband automatic gain control with high gain step accuracy

    International Nuclear Information System (INIS)

    He Xiaofeng; Ye Tianchun; Mo Taishan; Ma Chengyan

    2012-01-01

    An output amplitude configurable wideband automatic gain control (AGC) with high gain step accuracy for the GNSS receiver is presented. The amplitude of an AGC is configurable in order to cooperate with baseband chips to achieve interference suppression and be compatible with different full range ADCs. And what's more, the gain-boosting technology is introduced and the circuit is improved to increase the step accuracy. A zero, which is composed by the source feedback resistance and the source capacity, is introduced to compensate for the pole. The AGC is fabricated in a 0.18 μm CMOS process. The AGC shows a 62 dB gain control range by 1 dB each step with a gain error of less than 0.2 dB. The AGC provides 3 dB bandwidth larger than 80 MHz and the overall power consumption is less than 1.8 mA, and the die area is 800 × 300 μm 2 . (semiconductor integrated circuits)

  4. Accuracy of Handheld Blood Glucose Meters at High Altitude

    NARCIS (Netherlands)

    de Mol, Pieter; Krabbe, Hans G.; de Vries, Suzanna T.; Fokkert, Marion J.; Dikkeschei, Bert D.; Rienks, Rienk; Bilo, Karin M.; Bilo, Henk J. G.

    2010-01-01

    Background: Due to increasing numbers of people with diabetes taking part in extreme sports (e. g., high-altitude trekking), reliable handheld blood glucose meters (BGMs) are necessary. Accurate blood glucose measurement under extreme conditions is paramount for safe recreation at altitude. Prior

  5. Innovative Fiber-Optic Gyroscopes (FOGs) for High Accuracy Space Applications, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — This project aims to develop a compact, highly innovative Inertial Reference/Measurement Unit (IRU/IMU) that pushes the state-of-the-art in high accuracy performance...

  6. Influence of diffuse reflectance measurement accuracy on the scattering coefficient in determination of optical properties with integrating sphere optics (a secondary publication).

    Science.gov (United States)

    Horibe, Takuro; Ishii, Katsunori; Fukutomi, Daichi; Awazu, Kunio

    2015-12-30

    An estimation error of the scattering coefficient of hemoglobin in the high absorption wavelength range has been observed in optical property calculations of blood-rich tissues. In this study, the relationship between the accuracy of diffuse reflectance measurement in the integrating sphere and calculated scattering coefficient was evaluated with a system to calculate optical properties combined with an integrating sphere setup and the inverse Monte Carlo simulation. Diffuse reflectance was measured with the integrating sphere using a small incident port diameter and optical properties were calculated. As a result, the estimation error of the scattering coefficient was improved by accurate measurement of diffuse reflectance. In the high absorption wavelength range, the accuracy of diffuse reflectance measurement has an effect on the calculated scattering coefficient.

  7. Impact of a highly detailed emission inventory on modeling accuracy

    Science.gov (United States)

    Taghavi, M.; Cautenet, S.; Arteta, J.

    2005-03-01

    During Expérience sur Site pour COntraindre les Modèles de Pollution atmosphérique et de Transport d'Emissions (ESCOMPTE) campaign (June 10 to July 14, 2001), two pollution events observed during an intensive measurement period (IOP2a and IOP2b) have been simulated. The comprehensive Regional Atmospheric Modeling Systems (RAMS) model, version 4.3, coupled online with a chemical module including 29 species is used to follow the chemistry of a polluted zone over Southern France. This online method takes advantage of a parallel code and use of the powerful computer SGI 3800. Runs are performed with two emission inventories: the Emission Pre Inventory (EPI) and the Main Emission Inventory (MEI). The latter is more recent and has a high resolution. The redistribution of simulated chemical species (ozone and nitrogen oxides) is compared with aircraft and surface station measurements for both runs at regional scale. We show that the MEI inventory is more efficient than the EPI in retrieving the redistribution of chemical species in space (three-dimensional) and time. In surface stations, MEI is superior especially for primary species, like nitrogen oxides. The ozone pollution peaks obtained from an inventory, such as EPI, have a large uncertainty. To understand the realistic geographical distribution of pollutants and to obtain a good order of magnitude in ozone concentration (in space and time), a high-resolution inventory like MEI is necessary. Coupling RAMS-Chemistry with MEI provides a very efficient tool able to simulate pollution plumes even in a region with complex circulations, such as the ESCOMPTE zone.

  8. Switched-capacitor techniques for high-accuracy filter and ADC design

    NARCIS (Netherlands)

    Quinn, P.J.; Roermund, van A.H.M.

    2007-01-01

    Switched capacitor (SC) techniques are well proven to be excellent candidates for implementing critical analogue functions with high accuracy, surpassing other analogue techniques when embedded in mixed-signal CMOS VLSI. Conventional SC circuits are primarily limited in accuracy by a) capacitor

  9. High accuracy laboratory spectroscopy to support active greenhouse gas sensing

    Science.gov (United States)

    Long, D. A.; Bielska, K.; Cygan, A.; Havey, D. K.; Okumura, M.; Miller, C. E.; Lisak, D.; Hodges, J. T.

    2011-12-01

    Recent carbon dioxide (CO2) remote sensing missions have set precision targets as demanding as 0.25% (1 ppm) in order to elucidate carbon sources and sinks [1]. These ambitious measurement targets will require the most precise body of spectroscopic reference data ever assembled. Active sensing missions will be especially susceptible to subtle line shape effects as the narrow bandwidth of these measurements will greatly limit the number of spectral transitions which are employed in retrievals. In order to assist these remote sensing missions we have employed frequency-stabilized cavity ring-down spectroscopy (FS-CRDS) [2], a high-resolution, ultrasensitive laboratory technique, to measure precise line shape parameters for transitions of O2, CO2, and other atmospherically-relevant species within the near-infrared. These measurements have led to new HITRAN-style line lists for both 16O2 [3] and rare isotopologue [4] transitions in the A-band. In addition, we have performed detailed line shape studies of CO2 transitions near 1.6 μm under a variety of broadening conditions [5]. We will address recent measurements in these bands as well as highlight recent instrumental improvements to the FS-CRDS spectrometer. These improvements include the use of the Pound-Drever-Hall locking scheme, a high bandwidth servo which enables measurements to be made at rates greater than 10 kHz [6]. In addition, an optical frequency comb will be utilized as a frequency reference, which should allow for transition frequencies to be measured with uncertainties below 10 kHz (3×10-7 cm-1). [1] C. E. Miller, D. Crisp, P. L. DeCola, S. C. Olsen, et al., J. Geophys. Res.-Atmos. 112, D10314 (2007). [2] J. T. Hodges, H. P. Layer, W. W. Miller, G. E. Scace, Rev. Sci. Instrum. 75, 849-863 (2004). [3] D. A. Long, D. K. Havey, M. Okumura, C. E. Miller, et al., J. Quant. Spectrosc. Radiat. Transfer 111, 2021-2036 (2010). [4] D. A. Long, D. K. Havey, S. S. Yu, M. Okumura, et al., J. Quant. Spectrosc

  10. The accuracy of QCD perturbation theory at high energies

    CERN Document Server

    Dalla Brida, Mattia; Korzec, Tomasz; Ramos, Alberto; Sint, Stefan; Sommer, Rainer

    2016-01-01

    We discuss the determination of the strong coupling $\\alpha_\\mathrm{\\overline{MS}}^{}(m_\\mathrm{Z})$ or equivalently the QCD $\\Lambda$-parameter. Its determination requires the use of perturbation theory in $\\alpha_s(\\mu)$ in some scheme, $s$, and at some energy scale $\\mu$. The higher the scale $\\mu$ the more accurate perturbation theory becomes, owing to asymptotic freedom. As one step in our computation of the $\\Lambda$-parameter in three-flavor QCD, we perform lattice computations in a scheme which allows us to non-perturbatively reach very high energies, corresponding to $\\alpha_s = 0.1$ and below. We find that perturbation theory is very accurate there, yielding a three percent error in the $\\Lambda$-parameter, while data around $\\alpha_s \\approx 0.2$ is clearly insufficient to quote such a precision. It is important to realize that these findings are expected to be generic, as our scheme has advantageous properties regarding the applicability of perturbation theory.

  11. A New Three-Dimensional High-Accuracy Automatic Alignment System For Single-Mode Fibers

    Science.gov (United States)

    Yun-jiang, Rao; Shang-lian, Huang; Ping, Li; Yu-mei, Wen; Jun, Tang

    1990-02-01

    In order to achieve the low-loss splices of single-mode fibers, a new three-dimension high-accuracy automatic alignment system for single -mode fibers has been developed, which includes a new-type three-dimension high-resolution microdisplacement servo stage driven by piezoelectric elements, a new high-accuracy measurement system for the misalignment error of the fiber core-axis, and a special single chip microcomputer processing system. The experimental results show that alignment accuracy of ±0.1 pin with a movable stroke of -±20μm has been obtained. This new system has more advantages than that reported.

  12. Surface integrity and part accuracy in reaming and tapping stainless steel with new vegetable based cutting oils

    DEFF Research Database (Denmark)

    Belluco, Walter; De Chiffre, Leonardo

    2002-01-01

    This paper presents an investigation on the effect of new formulations of vegetable oils on surface integrity and part accuracy in reaming and tapping operations with AISI 316L stainless steel. Surface integrity was assessed with measurements of roughness, microhardness, and using metallographic...... as part accuracy. Cutting fluids based on vegetable oils showed comparable or better performance than mineral oils. ÆÉ2002 Published by Elsevier Science Ltd....... techniques, while part accuracy was measured on a coordinate measuring machine. A widely diffused commercial mineral oil was used as reference for all measurements. Cutting fluid was found to have a significant effect on surface integrity and thickness of the strain hardened layer in the sub-surface, as well...

  13. Accuracy Assessment for the Three-Dimensional Coordinates by High-Speed Videogrammetric Measurement

    Directory of Open Access Journals (Sweden)

    Xianglei Liu

    2018-01-01

    Full Text Available High-speed CMOS camera is a new kind of transducer to make the videogrammetric measurement for monitoring the displacement of high-speed shaking table structure. The purpose of this paper is to validate the three-dimensional coordinate accuracy of the shaking table structure acquired from the presented high-speed videogrammetric measuring system. In the paper, all of the key intermediate links are discussed, including the high-speed CMOS videogrammetric measurement system, the layout of the control network, the elliptical target detection, and the accuracy validation of final 3D spatial results. Through the accuracy analysis, the submillimeter accuracy can be made for the final the three-dimensional spatial coordinates which certify that the proposed high-speed videogrammetric technique is a better alternative technique which can replace the traditional transducer technique for monitoring the dynamic response for the shaking table structure.

  14. Improving accuracy for identifying related PubMed queries by an integrated approach.

    Science.gov (United States)

    Lu, Zhiyong; Wilbur, W John

    2009-10-01

    PubMed is the most widely used tool for searching biomedical literature online. As with many other online search tools, a user often types a series of multiple related queries before retrieving satisfactory results to fulfill a single information need. Meanwhile, it is also a common phenomenon to see a user type queries on unrelated topics in a single session. In order to study PubMed users' search strategies, it is necessary to be able to automatically separate unrelated queries and group together related queries. Here, we report a novel approach combining both lexical and contextual analyses for segmenting PubMed query sessions and identifying related queries and compare its performance with the previous approach based solely on concept mapping. We experimented with our integrated approach on sample data consisting of 1539 pairs of consecutive user queries in 351 user sessions. The prediction results of 1396 pairs agreed with the gold-standard annotations, achieving an overall accuracy of 90.7%. This demonstrates that our approach is significantly better than the previously published method. By applying this approach to a one day query log of PubMed, we found that a significant proportion of information needs involved more than one PubMed query, and that most of the consecutive queries for the same information need are lexically related. Finally, the proposed PubMed distance is shown to be an accurate and meaningful measure for determining the contextual similarity between biological terms. The integrated approach can play a critical role in handling real-world PubMed query log data as is demonstrated in our experiments.

  15. High-accuracy determination for optical indicatrix rotation in ferroelectric DTGS

    OpenAIRE

    O.S.Kushnir; O.A.Bevz; O.G.Vlokh

    2000-01-01

    Optical indicatrix rotation in deuterated ferroelectric triglycine sulphate is studied with the high-accuracy null-polarimetric technique. The behaviour of the effect in ferroelectric phase is referred to quadratic spontaneous electrooptics.

  16. The accuracy of MRI in assessing graft integrity after anterior cruciate ligament reconstruction

    International Nuclear Information System (INIS)

    Nakayama, Yoshihito; Shirai, Yasumasa; Narita, Tetsuya; Mori, Atsushi; Kobayashi, Kaoru

    2001-01-01

    To evaluate the efficacy of MRI in assessing anterior cruciate ligament (ACL) reconstruction graft integrity, we compared MRI findings with arthroscopic findings in 52 patients who had undergone arthroscopically assisted ACL reconstruction using semitendinosus and gracilis tendons augmented by woven polyester. MRI and arthroscopy were carried out 12 months after the operation. The MR appearance of ACL grafts was categorized into 3 types by signal intensity and continuity of the ligament according to Rak's method: well-defined type: the graft was visualized as a smoothly continuous band with low signal over the entire course; intermediate type: signal intensity increased and a low-signal band was visualized only in part of the graft; indiscernible type: the graft was not identified through the joint cavity due to markedly increased signal intensity. When the MR appearance of intermediate or indiscernible types was defined as torn, the grafts were presumed to be torn in 9 patients whose arthroscopic findings were 7 intact and 2 torn grafts. All cases with intact MRI findings were intact on arthroscopic examination. Thus, the sensitivity, specificity and accuracy of MRI as an evaluative tool for ACL graft tears were 100%, 86% and 86.5%, respectively. (author)

  17. Review of The SIAM 100-Digit Challenge: A Study in High-Accuracy Numerical Computing

    International Nuclear Information System (INIS)

    Bailey, David

    2005-01-01

    authors take the reader on a wide-ranging tour of modern numerical mathematics, with enough background material so that even readers with little or no training in numerical analysis can follow. Here is a list of just a few of the topics visited: numerical quadrature (i.e., numerical integration), series summation, sequence extrapolation, contour integration, Fourier integrals, high-precision arithmetic, interval arithmetic, symbolic computing, numerical linear algebra, perturbation theory, Euler-Maclaurin summation, global minimization, eigenvalue methods, evolutionary algorithms, matrix preconditioning, random walks, special functions, elliptic functions, Monte-Carlo methods, and numerical differentiation.

  18. Reactor dosimetry integral reaction rate data in LMFBR Benchmark and standard neutron fields: status, accuracy and implications

    International Nuclear Information System (INIS)

    Fabry, A.; Ceulemans, H.; Vandeplas, P.; McElroy, W.N.; Lippincott, E.P.

    1977-01-01

    This paper provides conclusions that may be drawn regarding the consistency and accuracy of dosimetry cross-section files on the basis of integral reaction rate data measured in U.S. and European benchmark and standard neutron fields. In a discussion of the major experimental facilities CFRMF (Idaho Falls), BIGTEN (Los Alamos), ΣΣ (Mol, Bucharest), NISUS (London), TAPIRO (Roma), FISSION SPECTRA (NBS, Mol, PTB), attention is paid to quantifying the sensitivity of computed integral data relative to the presently evaluated accuracy of the various neutron spectral distributions. The status of available integral data is reviewed and the assigned uncertainties are appraised, including experience gained by interlaboratory comparisons. For all reactions studied and for the various neutron fields, the measured integral data are compared to the ones computed from the ENDF/B-IV and the SAND-II dosimetry cross-section libraries as well as to some other differential data in relevant cases. This comparison, together with the proposed sensitivity and accuracy assessments, is used, whenever possible, to establish how well the best cross-sections evaluated on the basis of differential measurements (category I dosimetry reactions) are reliable in terms of integral reaction rates prediction and, for those reactions for which discrepancies are indicated, in which energy range it is presumed that additional differential measurements might help. For the other reactions (category II), the inconsistencies and trends are examined. The need for further integral measurements and interlaboratory comparisons is also considered

  19. Diagnostic accuracy of medical imagings and an integrated statistical approach to diagnosis. With special attention to hepatocellular carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Kawahira, Kosaburo

    1985-05-01

    Twenty-two patients with hepatocellular carcinoma and 36 without were clinically studied using angiography, computed tomography (CT), ultrasound (US) and Tc-99m phytate scintigraphy (RI). Diagnoses were confirmed by biopsy, surgery or autopsy, in all 58 patients. The judgement of multi-readers was obtained, independently. For a diagnosis of hepatocellular carcinoma, angiography was the most useful. Sensitivity, specificity and accuracy of this modality were 0.67, 0.85 and 0.78, respectively. Specificity and accuracy of US were 0.84 and 0.67, respectively, thereby US was the second best modality. CT was more useful than than RI for a diagnosis of hepatocellular carcinoma, in this series. Diagnostic accuracy of the 4 modalities in the diagnosis of liver mass were also discussed. To integrate these 4 images for a diagnosis of hepatocellular carcinoma, a multivariate analysis was made. The diagnostic accuracy of the system was considerably higher than that of any single modality.

  20. 16 CFR Appendix A to Part 660 - Interagency Guidelines Concerning the Accuracy and Integrity of Information Furnished to Consumer...

    Science.gov (United States)

    2010-01-01

    ... evaluation of its own practices, consumer reporting agency practices of which the furnisher is aware... Accuracy and Integrity of Information Furnished to Consumer Reporting Agencies A Appendix A to Part 660... INFORMATION TO CONSUMER REPORTING AGENCIES (eff. 07-01-10) Pt. 660, App. A Appendix A to Part 660—Interagency...

  1. Location Accuracy of INS/Gravity-Integrated Navigation System on the Basis of Ocean Experiment and Simulation.

    Science.gov (United States)

    Wang, Hubiao; Wu, Lin; Chai, Hua; Bao, Lifeng; Wang, Yong

    2017-12-20

    An experiment comparing the location accuracy of gravity matching-aided navigation in the ocean and simulation is very important to evaluate the feasibility and the performance of an INS/gravity-integrated navigation system (IGNS) in underwater navigation. Based on a 1' × 1' marine gravity anomaly reference map and multi-model adaptive Kalman filtering algorithm, a matching location experiment of IGNS was conducted using data obtained using marine gravimeter. The location accuracy under actual ocean conditions was 2.83 nautical miles (n miles). Several groups of simulated data of marine gravity anomalies were obtained by establishing normally distributed random error N ( u , σ 2 ) with varying mean u and noise variance σ 2 . Thereafter, the matching location of IGNS was simulated. The results show that the changes in u had little effect on the location accuracy. However, an increase in σ 2 resulted in a significant decrease in the location accuracy. A comparison between the actual ocean experiment and the simulation along the same route demonstrated the effectiveness of the proposed simulation method and quantitative analysis results. In addition, given the gravimeter (1-2 mGal accuracy) and the reference map (resolution 1' × 1'; accuracy 3-8 mGal), location accuracy of IGNS was up to reach ~1.0-3.0 n miles in the South China Sea.

  2. Applying recursive numerical integration techniques for solving high dimensional integrals

    International Nuclear Information System (INIS)

    Ammon, Andreas; Genz, Alan; Hartung, Tobias; Jansen, Karl; Volmer, Julia; Leoevey, Hernan

    2016-11-01

    The error scaling for Markov-Chain Monte Carlo techniques (MCMC) with N samples behaves like 1/√(N). This scaling makes it often very time intensive to reduce the error of computed observables, in particular for applications in lattice QCD. It is therefore highly desirable to have alternative methods at hand which show an improved error scaling. One candidate for such an alternative integration technique is the method of recursive numerical integration (RNI). The basic idea of this method is to use an efficient low-dimensional quadrature rule (usually of Gaussian type) and apply it iteratively to integrate over high-dimensional observables and Boltzmann weights. We present the application of such an algorithm to the topological rotor and the anharmonic oscillator and compare the error scaling to MCMC results. In particular, we demonstrate that the RNI technique shows an error scaling in the number of integration points m that is at least exponential.

  3. Applying recursive numerical integration techniques for solving high dimensional integrals

    Energy Technology Data Exchange (ETDEWEB)

    Ammon, Andreas [IVU Traffic Technologies AG, Berlin (Germany); Genz, Alan [Washington State Univ., Pullman, WA (United States). Dept. of Mathematics; Hartung, Tobias [King' s College, London (United Kingdom). Dept. of Mathematics; Jansen, Karl; Volmer, Julia [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC; Leoevey, Hernan [Humboldt Univ. Berlin (Germany). Inst. fuer Mathematik

    2016-11-15

    The error scaling for Markov-Chain Monte Carlo techniques (MCMC) with N samples behaves like 1/√(N). This scaling makes it often very time intensive to reduce the error of computed observables, in particular for applications in lattice QCD. It is therefore highly desirable to have alternative methods at hand which show an improved error scaling. One candidate for such an alternative integration technique is the method of recursive numerical integration (RNI). The basic idea of this method is to use an efficient low-dimensional quadrature rule (usually of Gaussian type) and apply it iteratively to integrate over high-dimensional observables and Boltzmann weights. We present the application of such an algorithm to the topological rotor and the anharmonic oscillator and compare the error scaling to MCMC results. In particular, we demonstrate that the RNI technique shows an error scaling in the number of integration points m that is at least exponential.

  4. The effect of pattern overlap on the accuracy of high resolution electron backscatter diffraction measurements

    Energy Technology Data Exchange (ETDEWEB)

    Tong, Vivian, E-mail: v.tong13@imperial.ac.uk [Department of Materials, Imperial College London, Prince Consort Road, London SW7 2AZ (United Kingdom); Jiang, Jun [Department of Materials, Imperial College London, Prince Consort Road, London SW7 2AZ (United Kingdom); Wilkinson, Angus J. [Department of Materials, University of Oxford, Parks Road, Oxford OX1 3PH (United Kingdom); Britton, T. Ben [Department of Materials, Imperial College London, Prince Consort Road, London SW7 2AZ (United Kingdom)

    2015-08-15

    High resolution, cross-correlation-based, electron backscatter diffraction (EBSD) measures the variation of elastic strains and lattice rotations from a reference state. Regions near grain boundaries are often of interest but overlap of patterns from the two grains could reduce accuracy of the cross-correlation analysis. To explore this concern, patterns from the interior of two grains have been mixed to simulate the interaction volume crossing a grain boundary so that the effect on the accuracy of the cross correlation results can be tested. It was found that the accuracy of HR-EBSD strain measurements performed in a FEG-SEM on zirconium remains good until the incident beam is less than 18 nm from a grain boundary. A simulated microstructure was used to measure how often pattern overlap occurs at any given EBSD step size, and a simple relation was found linking the probability of overlap with step size. - Highlights: • Pattern overlap occurs at grain boundaries and reduces HR-EBSD accuracy. • A test is devised to measure the accuracy of HR-EBSD in the presence of overlap. • High pass filters can sometimes, but not generally, improve HR-EBSD measurements. • Accuracy of HR-EBSD remains high until the reference pattern intensity is <72%. • 9% of points near a grain boundary will have significant error for 200nm step size in Zircaloy-4.

  5. Future demands highly integrated solutions

    Energy Technology Data Exchange (ETDEWEB)

    Mangler, Andreas [Rutronik Elektronische Bauelemente GmbH, Ispringen (Germany). Strategic Marketing

    2010-07-01

    The future energy supply with a high number of decentral power plants depends on the use of innovative system technology. It is a precondition for a well-functioning grid and power management over all voltage levels. (orig.)

  6. Optimal design of a high accuracy photoelectric auto-collimator based on position sensitive detector

    Science.gov (United States)

    Yan, Pei-pei; Yang, Yong-qing; She, Wen-ji; Liu, Kai; Jiang, Kai; Duan, Jing; Shan, Qiusha

    2018-02-01

    A kind of high accuracy Photo-electric auto-collimator based on PSD was designed. The integral structure composed of light source, optical lens group, Position Sensitive Detector (PSD) sensor, and its hardware and software processing system constituted. Telephoto objective optical type is chosen during the designing process, which effectively reduces the length, weight and volume of the optical system, as well as develops simulation-based design and analysis of the auto-collimator optical system. The technical indicators of auto-collimator presented by this paper are: measuring resolution less than 0.05″; a field of view is 2ω=0.4° × 0.4° measuring range is +/-5' error of whole range measurement is less than 0.2″. Measuring distance is 10m, which are applicable to minor-angle precise measuring environment. Aberration analysis indicates that the MTF close to the diffraction limit, the spot in the spot diagram is much smaller than the Airy disk. The total length of the telephoto lens is only 450mm by the design of the optical machine structure optimization. The autocollimator's dimension get compact obviously under the condition of the image quality is guaranteed.

  7. High-accuracy drilling with an image guided light weight robot: autonomous versus intuitive feed control.

    Science.gov (United States)

    Tauscher, Sebastian; Fuchs, Alexander; Baier, Fabian; Kahrs, Lüder A; Ortmaier, Tobias

    2017-10-01

    Assistance of robotic systems in the operating room promises higher accuracy and, hence, demanding surgical interventions become realisable (e.g. the direct cochlear access). Additionally, an intuitive user interface is crucial for the use of robots in surgery. Torque sensors in the joints can be employed for intuitive interaction concepts. Regarding the accuracy, they lead to a lower structural stiffness and, thus, to an additional error source. The aim of this contribution is to examine, if an accuracy needed for demanding interventions can be achieved by such a system or not. Feasible accuracy results of the robot-assisted process depend on each work-flow step. This work focuses on the determination of the tool coordinate frame. A method for drill axis definition is implemented and analysed. Furthermore, a concept of admittance feed control is developed. This allows the user to control feeding along the planned path by applying a force to the robots structure. The accuracy is researched by drilling experiments with a PMMA phantom and artificial bone blocks. The described drill axis estimation process results in a high angular repeatability ([Formula: see text]). In the first set of drilling results, an accuracy of [Formula: see text] at entrance and [Formula: see text] at target point excluding imaging was achieved. With admittance feed control an accuracy of [Formula: see text] at target point was realised. In a third set twelve holes were drilled in artificial temporal bone phantoms including imaging. In this set-up an error of [Formula: see text] and [Formula: see text] was achieved. The results of conducted experiments show that accuracy requirements for demanding procedures such as the direct cochlear access can be fulfilled with compliant systems. Furthermore, it was shown that with the presented admittance feed control an accuracy of less then [Formula: see text] is achievable.

  8. Adaptive sensor-based ultra-high accuracy solar concentrator tracker

    Science.gov (United States)

    Brinkley, Jordyn; Hassanzadeh, Ali

    2017-09-01

    Conventional solar trackers use information of the sun's position, either by direct sensing or by GPS. Our method uses the shading of the receiver. This, coupled with nonimaging optics design allows us to achieve ultra-high concentration. Incorporating a sensor based shadow tracking method with a two stage concentration solar hybrid parabolic trough allows the system to maintain high concentration with acute accuracy.

  9. Enhancement accuracy of approximated solutions of the nonlinear singular integral equations of Chew-Low type

    International Nuclear Information System (INIS)

    Zhidkov, E.P.; Nguen Mong; Khoromskij, B.N.

    1979-01-01

    The ways of enhancement of the accuracy of approximate solutions of the Chew-Low type equation are considered. Difference schemes are proposed which allow one to obtain solution expansion in degrees of lattice step. On the basis of the expansion by the Richardson method the refinement of approximated solutions is made. Besides, the iteration process is constructed which reduces immediately to the solution of enhanced accuracy. The efficiency of the methods proposed is illustrated by numerical examples

  10. The research of digital circuit system for high accuracy CCD of portable Raman spectrometer

    Science.gov (United States)

    Yin, Yu; Cui, Yongsheng; Zhang, Xiuda; Yan, Huimin

    2013-08-01

    The Raman spectrum technology is widely used for it can identify various types of molecular structure and material. The portable Raman spectrometer has become a hot direction of the spectrometer development nowadays for its convenience in handheld operation and real-time detection which is superior to traditional Raman spectrometer with heavy weight and bulky size. But there is still a gap for its measurement sensitivity between portable and traditional devices. However, portable Raman Spectrometer with Shell-Isolated Nanoparticle-Enhanced Raman Spectroscopy (SHINERS) technology can enhance the Raman signal significantly by several orders of magnitude, giving consideration in both measurement sensitivity and mobility. This paper proposed a design and implementation of driver and digital circuit for high accuracy CCD sensor, which is core part of portable spectrometer. The main target of the whole design is to reduce the dark current generation rate and increase signal sensitivity during the long integration time, and in the weak signal environment. In this case, we use back-thinned CCD image sensor from Hamamatsu Corporation with high sensitivity, low noise and large dynamic range. In order to maximize this CCD sensor's performance and minimize the whole size of the device simultaneously to achieve the project indicators, we delicately designed a peripheral circuit for the CCD sensor. The design is mainly composed with multi-voltage circuit, sequential generation circuit, driving circuit and A/D transition parts. As the most important power supply circuit, the multi-voltage circuits with 12 independent voltages are designed with reference power supply IC and set to specified voltage value by the amplifier making up the low-pass filter, which allows the user to obtain a highly stable and accurate voltage with low noise. What's more, to make our design easy to debug, CPLD is selected to generate sequential signal. The A/D converter chip consists of a correlated

  11. Resonance integral calculations for high temperature reactors

    International Nuclear Information System (INIS)

    Blake, J.P.H.

    1960-02-01

    Methods of calculation of resonance integrals of finite dilution and temperature are given for both, homogeneous and heterogeneous geometries, together with results obtained from these methods as applied to the design of high temperature reactors. (author)

  12. Reduced Set of Virulence Genes Allows High Accuracy Prediction of Bacterial Pathogenicity in Humans

    Science.gov (United States)

    Iraola, Gregorio; Vazquez, Gustavo; Spangenberg, Lucía; Naya, Hugo

    2012-01-01

    Although there have been great advances in understanding bacterial pathogenesis, there is still a lack of integrative information about what makes a bacterium a human pathogen. The advent of high-throughput sequencing technologies has dramatically increased the amount of completed bacterial genomes, for both known human pathogenic and non-pathogenic strains; this information is now available to investigate genetic features that determine pathogenic phenotypes in bacteria. In this work we determined presence/absence patterns of different virulence-related genes among more than finished bacterial genomes from both human pathogenic and non-pathogenic strains, belonging to different taxonomic groups (i.e: Actinobacteria, Gammaproteobacteria, Firmicutes, etc.). An accuracy of 95% using a cross-fold validation scheme with in-fold feature selection is obtained when classifying human pathogens and non-pathogens. A reduced subset of highly informative genes () is presented and applied to an external validation set. The statistical model was implemented in the BacFier v1.0 software (freely available at ), that displays not only the prediction (pathogen/non-pathogen) and an associated probability for pathogenicity, but also the presence/absence vector for the analyzed genes, so it is possible to decipher the subset of virulence genes responsible for the classification on the analyzed genome. Furthermore, we discuss the biological relevance for bacterial pathogenesis of the core set of genes, corresponding to eight functional categories, all with evident and documented association with the phenotypes of interest. Also, we analyze which functional categories of virulence genes were more distinctive for pathogenicity in each taxonomic group, which seems to be a completely new kind of information and could lead to important evolutionary conclusions. PMID:22916122

  13. TotalReCaller: improved accuracy and performance via integrated alignment and base-calling.

    Science.gov (United States)

    Menges, Fabian; Narzisi, Giuseppe; Mishra, Bud

    2011-09-01

    Currently, re-sequencing approaches use multiple modules serially to interpret raw sequencing data from next-generation sequencing platforms, while remaining oblivious to the genomic information until the final alignment step. Such approaches fail to exploit the full information from both raw sequencing data and the reference genome that can yield better quality sequence reads, SNP-calls, variant detection, as well as an alignment at the best possible location in the reference genome. Thus, there is a need for novel reference-guided bioinformatics algorithms for interpreting analog signals representing sequences of the bases ({A, C, G, T}), while simultaneously aligning possible sequence reads to a source reference genome whenever available. Here, we propose a new base-calling algorithm, TotalReCaller, to achieve improved performance. A linear error model for the raw intensity data and Burrows-Wheeler transform (BWT) based alignment are combined utilizing a Bayesian score function, which is then globally optimized over all possible genomic locations using an efficient branch-and-bound approach. The algorithm has been implemented in soft- and hardware [field-programmable gate array (FPGA)] to achieve real-time performance. Empirical results on real high-throughput Illumina data were used to evaluate TotalReCaller's performance relative to its peers-Bustard, BayesCall, Ibis and Rolexa-based on several criteria, particularly those important in clinical and scientific applications. Namely, it was evaluated for (i) its base-calling speed and throughput, (ii) its read accuracy and (iii) its specificity and sensitivity in variant calling. A software implementation of TotalReCaller as well as additional information, is available at: http://bioinformatics.nyu.edu/wordpress/projects/totalrecaller/ fabian.menges@nyu.edu.

  14. An integrated open framework for thermodynamics of reactions that combines accuracy and coverage.

    Science.gov (United States)

    Noor, Elad; Bar-Even, Arren; Flamholz, Avi; Lubling, Yaniv; Davidi, Dan; Milo, Ron

    2012-08-01

    The laws of thermodynamics describe a direct, quantitative relationship between metabolite concentrations and reaction directionality. Despite great efforts, thermodynamic data suffer from limited coverage, scattered accessibility and non-standard annotations. We present a framework for unifying thermodynamic data from multiple sources and demonstrate two new techniques for extrapolating the Gibbs energies of unmeasured reactions and conditions. Both methods account for changes in cellular conditions (pH, ionic strength, etc.) by using linear regression over the ΔG(○) of pseudoisomers and reactions. The Pseudoisomeric Reactant Contribution method systematically infers compound formation energies using measured K' and pK(a) data. The Pseudoisomeric Group Contribution method extends the group contribution method and achieves a high coverage of unmeasured reactions. We define a continuous index that predicts the reversibility of a reaction under a given physiological concentration range. In the characteristic physiological range 3μM-3mM, we find that roughly half of the reactions in Escherichia coli's metabolism are reversible. These new tools can increase the accuracy of thermodynamic-based models, especially in non-standard pH and ionic strengths. The reversibility index can help modelers decide which reactions are reversible in physiological conditions. Freely available on the web at: http://equilibrator.weizmann.ac.il. Website implemented in Python, MySQL, Apache and Django, with all major browsers supported. The framework is open-source (code.google.com/p/milo-lab), implemented in pure Python and tested mainly on Linux. ron.milo@weizmann.ac.il Supplementary data are available at Bioinformatics online.

  15. An integrated open framework for thermodynamics of reactions that combines accuracy and coverage

    Science.gov (United States)

    Noor, Elad; Bar-Even, Arren; Flamholz, Avi; Lubling, Yaniv; Davidi, Dan; Milo, Ron

    2012-01-01

    Motivation: The laws of thermodynamics describe a direct, quantitative relationship between metabolite concentrations and reaction directionality. Despite great efforts, thermodynamic data suffer from limited coverage, scattered accessibility and non-standard annotations. We present a framework for unifying thermodynamic data from multiple sources and demonstrate two new techniques for extrapolating the Gibbs energies of unmeasured reactions and conditions. Results: Both methods account for changes in cellular conditions (pH, ionic strength, etc.) by using linear regression over the ΔG○ of pseudoisomers and reactions. The Pseudoisomeric Reactant Contribution method systematically infers compound formation energies using measured K′ and pKa data. The Pseudoisomeric Group Contribution method extends the group contribution method and achieves a high coverage of unmeasured reactions. We define a continuous index that predicts the reversibility of a reaction under a given physiological concentration range. In the characteristic physiological range 3μM–3mM, we find that roughly half of the reactions in Escherichia coli's metabolism are reversible. These new tools can increase the accuracy of thermodynamic-based models, especially in non-standard pH and ionic strengths. The reversibility index can help modelers decide which reactions are reversible in physiological conditions. Availability: Freely available on the web at: http://equilibrator.weizmann.ac.il. Website implemented in Python, MySQL, Apache and Django, with all major browsers supported. The framework is open-source (code.google.com/p/milo-lab), implemented in pure Python and tested mainly on Linux. Contact: ron.milo@weizmann.ac.il Supplementary Information: Supplementary data are available at Bioinformatics online. PMID:22645166

  16. High performance bio-integrated devices

    Science.gov (United States)

    Kim, Dae-Hyeong; Lee, Jongha; Park, Minjoon

    2014-06-01

    In recent years, personalized electronics for medical applications, particularly, have attracted much attention with the rise of smartphones because the coupling of such devices and smartphones enables the continuous health-monitoring in patients' daily life. Especially, it is expected that the high performance biomedical electronics integrated with the human body can open new opportunities in the ubiquitous healthcare. However, the mechanical and geometrical constraints inherent in all standard forms of high performance rigid wafer-based electronics raise unique integration challenges with biotic entities. Here, we describe materials and design constructs for high performance skin-mountable bio-integrated electronic devices, which incorporate arrays of single crystalline inorganic nanomembranes. The resulting electronic devices include flexible and stretchable electrophysiology electrodes and sensors coupled with active electronic components. These advances in bio-integrated systems create new directions in the personalized health monitoring and/or human-machine interfaces.

  17. A comparison of the accuracy of pixel based and object based classifications of integrated optical and LiDAR data

    Science.gov (United States)

    Gajda, Agnieszka; Wójtowicz-Nowakowska, Anna

    2013-04-01

    A comparison of the accuracy of pixel based and object based classifications of integrated optical and LiDAR data Land cover maps are generally produced on the basis of high resolution imagery. Recently, LiDAR (Light Detection and Ranging) data have been brought into use in diverse applications including land cover mapping. In this study we attempted to assess the accuracy of land cover classification using both high resolution aerial imagery and LiDAR data (airborne laser scanning, ALS), testing two classification approaches: a pixel-based classification and object-oriented image analysis (OBIA). The study was conducted on three test areas (3 km2 each) in the administrative area of Kraków, Poland, along the course of the Vistula River. They represent three different dominating land cover types of the Vistula River valley. Test site 1 had a semi-natural vegetation, with riparian forests and shrubs, test site 2 represented a densely built-up area, and test site 3 was an industrial site. Point clouds from ALS and ortophotomaps were both captured in November 2007. Point cloud density was on average 16 pt/m2 and it contained additional information about intensity and encoded RGB values. Ortophotomaps had a spatial resolution of 10 cm. From point clouds two raster maps were generated: intensity (1) and (2) normalised Digital Surface Model (nDSM), both with the spatial resolution of 50 cm. To classify the aerial data, a supervised classification approach was selected. Pixel based classification was carried out in ERDAS Imagine software. Ortophotomaps and intensity and nDSM rasters were used in classification. 15 homogenous training areas representing each cover class were chosen. Classified pixels were clumped to avoid salt and pepper effect. Object oriented image object classification was carried out in eCognition software, which implements both the optical and ALS data. Elevation layers (intensity, firs/last reflection, etc.) were used at segmentation stage due to

  18. Registration area and accuracy when integrating laser-scanned and maxillofacial cone-beam computed tomography images.

    Science.gov (United States)

    Sun, LiJun; Hwang, Hyeon-Shik; Lee, Kyung-Min

    2018-03-01

    The purpose of this study was to examine changes in registration accuracy after including occlusal surface and incisal edge areas in addition to the buccal surface when integrating laser-scanned and maxillofacial cone-beam computed tomography (CBCT) dental images. CBCT scans and maxillary dental casts were obtained from 30 patients. Three methods were used to integrate the images: R1, only the buccal and labial surfaces were used; R2, the incisal edges of the anterior teeth and the buccal and distal marginal ridges of the second molars were used; and R3, labial surfaces, including incisal edges of anterior teeth, and buccal surfaces, including buccal and distal marginal ridges of the second molars, were used. Differences between the 2 images were evaluated by color-mapping methods and average surface distances by measuring the 3-dimensional Euclidean distances between the surface points on the 2 images. The R1 method showed more discrepancies between the laser-scanned and CBCT images than did the other methods. The R2 method did not show a significant difference in registration accuracy compared with the R3 method. The results of this study indicate that accuracy when integrating laser-scanned dental images into maxillofacial CBCT images can be increased by including occlusal surface and incisal edge areas as registration areas. Copyright © 2017 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.

  19. Accuracy of hiatal hernia detection with esophageal high-resolution manometry

    NARCIS (Netherlands)

    Weijenborg, P. W.; van Hoeij, F. B.; Smout, A. J. P. M.; Bredenoord, A. J.

    2015-01-01

    The diagnosis of a sliding hiatal hernia is classically made with endoscopy or barium esophagogram. Spatial separation of the lower esophageal sphincter (LES) and diaphragm, the hallmark of hiatal hernia, can also be observed on high-resolution manometry (HRM), but the diagnostic accuracy of this

  20. High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast

    DEFF Research Database (Denmark)

    Gnad, Florian; de Godoy, Lyris M F; Cox, Jürgen

    2009-01-01

    Protein phosphorylation is a fundamental regulatory mechanism that affects many cell signaling processes. Using high-accuracy MS and stable isotope labeling in cell culture-labeling, we provide a global view of the Saccharomyces cerevisiae phosphoproteome, containing 3620 phosphorylation sites ma...

  1. High accuracy positioning using carrier-phases with the opensource GPSTK software

    OpenAIRE

    Salazar Hernández, Dagoberto José; Hernández Pajares, Manuel; Juan Zornoza, José Miguel; Sanz Subirana, Jaume

    2008-01-01

    The objective of this work is to show how using a proper GNSS data management strategy, combined with the flexibility provided by the open source "GPS Toolkit" (GPSTk), it is possible to easily develop both simple code-based processing strategies as well as basic high accuracy carrier-phase positioning techniques like Precise Point Positioning (PPP

  2. Very high-accuracy calibration of radiation pattern and gain of a near-field probe

    DEFF Research Database (Denmark)

    Pivnenko, Sergey; Nielsen, Jeppe Majlund; Breinbjerg, Olav

    2014-01-01

    In this paper, very high-accuracy calibration of the radiation pattern and gain of a near-field probe is described. An open-ended waveguide near-field probe has been used in a recent measurement of the C-band Synthetic Aperture Radar (SAR) Antenna Subsystem for the Sentinel 1 mission of the Europ...

  3. From journal to headline: the accuracy of climate science news in Danish high quality newspapers

    DEFF Research Database (Denmark)

    Vestergård, Gunver Lystbæk

    2011-01-01

    analysis to examine the accuracy of Danish high quality newspapers in quoting scientific publications from 1997 to 2009. Out of 88 articles, 46 contained inaccuracies though the majority was found to be insignificant and random. The study concludes that Danish broadsheet newspapers are ‘moderately...

  4. High-order passive photonic temporal integrators.

    Science.gov (United States)

    Asghari, Mohammad H; Wang, Chao; Yao, Jianping; Azaña, José

    2010-04-15

    We experimentally demonstrate, for the first time to our knowledge, an ultrafast photonic high-order (second-order) complex-field temporal integrator. The demonstrated device uses a single apodized uniform-period fiber Bragg grating (FBG), and it is based on a general FBG design approach for implementing optimized arbitrary-order photonic passive temporal integrators. Using this same design approach, we also fabricate and test a first-order passive temporal integrator offering an energetic-efficiency improvement of more than 1 order of magnitude as compared with previously reported passive first-order temporal integrators. Accurate and efficient first- and second-order temporal integrations of ultrafast complex-field optical signals (with temporal features as fast as approximately 2.5ps) are successfully demonstrated using the fabricated FBG devices.

  5. Functional knowledge transfer for high-accuracy prediction of under-studied biological processes.

    Directory of Open Access Journals (Sweden)

    Christopher Y Park

    Full Text Available A key challenge in genetics is identifying the functional roles of genes in pathways. Numerous functional genomics techniques (e.g. machine learning that predict protein function have been developed to address this question. These methods generally build from existing annotations of genes to pathways and thus are often unable to identify additional genes participating in processes that are not already well studied. Many of these processes are well studied in some organism, but not necessarily in an investigator's organism of interest. Sequence-based search methods (e.g. BLAST have been used to transfer such annotation information between organisms. We demonstrate that functional genomics can complement traditional sequence similarity to improve the transfer of gene annotations between organisms. Our method transfers annotations only when functionally appropriate as determined by genomic data and can be used with any prediction algorithm to combine transferred gene function knowledge with organism-specific high-throughput data to enable accurate function prediction. We show that diverse state-of-art machine learning algorithms leveraging functional knowledge transfer (FKT dramatically improve their accuracy in predicting gene-pathway membership, particularly for processes with little experimental knowledge in an organism. We also show that our method compares favorably to annotation transfer by sequence similarity. Next, we deploy FKT with state-of-the-art SVM classifier to predict novel genes to 11,000 biological processes across six diverse organisms and expand the coverage of accurate function predictions to processes that are often ignored because of a dearth of annotated genes in an organism. Finally, we perform in vivo experimental investigation in Danio rerio and confirm the regulatory role of our top predicted novel gene, wnt5b, in leftward cell migration during heart development. FKT is immediately applicable to many bioinformatics

  6. Technics study on high accuracy crush dressing and sharpening of diamond grinding wheel

    Science.gov (United States)

    Jia, Yunhai; Lu, Xuejun; Li, Jiangang; Zhu, Lixin; Song, Yingjie

    2011-05-01

    Mechanical grinding of artificial diamond grinding wheel was traditional wheel dressing process. The rotate speed and infeed depth of tool wheel were main technics parameters. The suitable technics parameters of metals-bonded diamond grinding wheel and resin-bonded diamond grinding wheel high accuracy crush dressing were obtained by a mount of experiment in super-hard material wheel dressing grind machine and by analysis of grinding force. In the same time, the effect of machine sharpening and sprinkle granule sharpening was contrasted. These analyses and lots of experiments had extent instruction significance to artificial diamond grinding wheel accuracy crush dressing.

  7. Comparison of the accuracy of the calibration model on the double and single integrating sphere systems

    CSIR Research Space (South Africa)

    Singh, A

    2011-05-01

    Full Text Available . In this instance the samples are made using different concentrations of intralipid and black ink. The total and diffuse transmittance and reflectance is measured on both setups and the accuracy of each model compared by evaluating the prediction errors...

  8. Integration of genomic information into sport horse breeding programs for optimization of accuracy of selection.

    Science.gov (United States)

    Haberland, A M; König von Borstel, U; Simianer, H; König, S

    2012-09-01

    Reliable selection criteria are required for young riding horses to increase genetic gain by increasing accuracy of selection and decreasing generation intervals. In this study, selection strategies incorporating genomic breeding values (GEBVs) were evaluated. Relevant stages of selection in sport horse breeding programs were analyzed by applying selection index theory. Results in terms of accuracies of indices (r(TI) ) and relative selection response indicated that information on single nucleotide polymorphism (SNP) genotypes considerably increases the accuracy of breeding values estimated for young horses without own or progeny performance. In a first scenario, the correlation between the breeding value estimated from the SNP genotype and the true breeding value (= accuracy of GEBV) was fixed to a relatively low value of r(mg) = 0.5. For a low heritability trait (h(2) = 0.15), and an index for a young horse based only on information from both parents, additional genomic information doubles r(TI) from 0.27 to 0.54. Including the conventional information source 'own performance' into the before mentioned index, additional SNP information increases r(TI) by 40%. Thus, particularly with regard to traits of low heritability, genomic information can provide a tool for well-founded selection decisions early in life. In a further approach, different sources of breeding values (e.g. GEBV and estimated breeding values (EBVs) from different countries) were combined into an overall index when altering accuracies of EBVs and correlations between traits. In summary, we showed that genomic selection strategies have the potential to contribute to a substantial reduction in generation intervals in horse breeding programs.

  9. High accuracy interface characterization of three phase material systems in three dimensions

    DEFF Research Database (Denmark)

    Jørgensen, Peter Stanley; Hansen, Karin Vels; Larsen, Rasmus

    2010-01-01

    Quantification of interface properties such as two phase boundary area and triple phase boundary length is important in the characterization ofmanymaterial microstructures, in particular for solid oxide fuel cell electrodes. Three-dimensional images of these microstructures can be obtained...... by tomography schemes such as focused ion beam serial sectioning or micro-computed tomography. We present a high accuracy method of calculating two phase surface areas and triple phase length of triple phase systems from subvoxel accuracy segmentations of constituent phases. The method performs a three phase...... polygonization of the interface boundaries which results in a non-manifold mesh of connected faces. We show how the triple phase boundaries can be extracted as connected curve loops without branches. The accuracy of the method is analyzed by calculations on geometrical primitives...

  10. Automated novel high-accuracy miniaturized positioning system for use in analytical instrumentation

    Science.gov (United States)

    Siomos, Konstadinos; Kaliakatsos, John; Apostolakis, Manolis; Lianakis, John; Duenow, Peter

    1996-01-01

    The development of three-dimensional automotive devices (micro-robots) for applications in analytical instrumentation, clinical chemical diagnostics and advanced laser optics, depends strongly on the ability of such a device: firstly to be positioned with high accuracy, reliability, and automatically, by means of user friendly interface techniques; secondly to be compact; and thirdly to operate under vacuum conditions, free of most of the problems connected with conventional micropositioners using stepping-motor gear techniques. The objective of this paper is to develop and construct a mechanically compact computer-based micropositioning system for coordinated motion in the X-Y-Z directions with: (1) a positioning accuracy of less than 1 micrometer, (the accuracy of the end-position of the system is controlled by a hard/software assembly using a self-constructed optical encoder); (2) a heat-free propulsion mechanism for vacuum operation; and (3) synchronized X-Y motion.

  11. High Accuracy Acoustic Relative Humidity Measurement inDuct Flow with Air

    Directory of Open Access Journals (Sweden)

    Cees van der Geld

    2010-08-01

    Full Text Available An acoustic relative humidity sensor for air-steam mixtures in duct flow is designed and tested. Theory, construction, calibration, considerations on dynamic response and results are presented. The measurement device is capable of measuring line averaged values of gas velocity, temperature and relative humidity (RH instantaneously, by applying two ultrasonic transducers and an array of four temperature sensors. Measurement ranges are: gas velocity of 0–12 m/s with an error of ±0.13 m/s, temperature 0–100 °C with an error of ±0.07 °C and relative humidity 0–100% with accuracy better than 2 % RH above 50 °C. Main advantage over conventional humidity sensors is the high sensitivity at high RH at temperatures exceeding 50 °C, with accuracy increasing with increasing temperature. The sensors are non-intrusive and resist highly humid environments.

  12. High accuracy acoustic relative humidity measurement in duct flow with air.

    Science.gov (United States)

    van Schaik, Wilhelm; Grooten, Mart; Wernaart, Twan; van der Geld, Cees

    2010-01-01

    An acoustic relative humidity sensor for air-steam mixtures in duct flow is designed and tested. Theory, construction, calibration, considerations on dynamic response and results are presented. The measurement device is capable of measuring line averaged values of gas velocity, temperature and relative humidity (RH) instantaneously, by applying two ultrasonic transducers and an array of four temperature sensors. Measurement ranges are: gas velocity of 0-12 m/s with an error of ± 0.13 m/s, temperature 0-100 °C with an error of ± 0.07 °C and relative humidity 0-100% with accuracy better than 2 % RH above 50 °C. Main advantage over conventional humidity sensors is the high sensitivity at high RH at temperatures exceeding 50 °C, with accuracy increasing with increasing temperature. The sensors are non-intrusive and resist highly humid environments.

  13. A proposal for limited criminal liability in high-accuracy endoscopic sinus surgery.

    Science.gov (United States)

    Voultsos, P; Casini, M; Ricci, G; Tambone, V; Midolo, E; Spagnolo, A G

    2017-02-01

    The aim of the present study is to propose legal reform limiting surgeons' criminal liability in high-accuracy and high-risk surgery such as endoscopic sinus surgery (ESS). The study includes a review of the medical literature, focusing on identifying and examining reasons why ESS carries a very high risk of serious complications related to inaccurate surgical manoeuvers and reviewing British and Italian legal theory and case-law on medical negligence, especially with regard to Italian Law 189/2012 (so called "Balduzzi" Law). It was found that serious complications due to inaccurate surgical manoeuvers may occur in ESS regardless of the skill, experience and prudence/diligence of the surgeon. Subjectivity should be essential to medical negligence, especially regarding high-accuracy surgery. Italian Law 189/2012 represents a good basis for the limitation of criminal liability resulting from inaccurate manoeuvres in high-accuracy surgery such as ESS. It is concluded that ESS surgeons should be relieved of criminal liability in cases of simple/ordinary negligence where guidelines have been observed. © Copyright by Società Italiana di Otorinolaringologia e Chirurgia Cervico-Facciale, Rome, Italy.

  14. High Accuracy Evaluation of the Finite Fourier Transform Using Sampled Data

    Science.gov (United States)

    Morelli, Eugene A.

    1997-01-01

    Many system identification and signal processing procedures can be done advantageously in the frequency domain. A required preliminary step for this approach is the transformation of sampled time domain data into the frequency domain. The analytical tool used for this transformation is the finite Fourier transform. Inaccuracy in the transformation can degrade system identification and signal processing results. This work presents a method for evaluating the finite Fourier transform using cubic interpolation of sampled time domain data for high accuracy, and the chirp Zeta-transform for arbitrary frequency resolution. The accuracy of the technique is demonstrated in example cases where the transformation can be evaluated analytically. Arbitrary frequency resolution is shown to be important for capturing details of the data in the frequency domain. The technique is demonstrated using flight test data from a longitudinal maneuver of the F-18 High Alpha Research Vehicle.

  15. High-Accuracy Spherical Near-Field Measurements for Satellite Antenna Testing

    DEFF Research Database (Denmark)

    Breinbjerg, Olav

    2017-01-01

    The spherical near-field antenna measurement technique is unique in combining several distinct advantages and it generally constitutes the most accurate technique for experimental characterization of radiation from antennas. From the outset in 1970, spherical near-field antenna measurements have...... matured into a well-established technique that is widely used for testing antennas for many wireless applications. In particular, for high-accuracy applications, such as remote sensing satellite missions in ESA's Earth Observation Programme with uncertainty requirements at the level of 0.05dB - 0.10d......B, the spherical near-field antenna measurement technique is generally superior. This paper addresses the means to achieving high measurement accuracy; these include the measurement technique per se, its implementation in terms of proper measurement procedures, the use of uncertainty estimates, as well as facility...

  16. A New Approach to High-accuracy Road Orthophoto Mapping Based on Wavelet Transform

    Directory of Open Access Journals (Sweden)

    Ming Yang

    2011-12-01

    Full Text Available Existing orthophoto map based on satellite photography and aerial photography is not precise enough for road marking. This paper proposes a new approach to high-accuracy orthophoto mapping. The approach uses inverse perspective transformation to process the image information and generates the orthophoto fragment. The offline interpolation algorithm is used to process the location information. It processes the dead reckoning and the EKF location information, and uses the result to transform the fragments to the global coordinate system. At last it uses wavelet transform to divides the image to two frequency bands and uses weighted median algorithm to deal with them separately. The result of experiment shows that the map produced with this method has high accuracy.

  17. Surgical Navigation Technology Based on Augmented Reality and Integrated 3D Intraoperative Imaging: A Spine Cadaveric Feasibility and Accuracy Study.

    Science.gov (United States)

    Elmi-Terander, Adrian; Skulason, Halldor; Söderman, Michael; Racadio, John; Homan, Robert; Babic, Drazenko; van der Vaart, Nijs; Nachabe, Rami

    2016-11-01

    A cadaveric laboratory study. The aim of this study was to assess the feasibility and accuracy of thoracic pedicle screw placement using augmented reality surgical navigation (ARSN). Recent advances in spinal navigation have shown improved accuracy in lumbosacral pedicle screw placement but limited benefits in the thoracic spine. 3D intraoperative imaging and instrument navigation may allow improved accuracy in pedicle screw placement, without the use of x-ray fluoroscopy, and thus opens the route to image-guided minimally invasive therapy in the thoracic spine. ARSN encompasses a surgical table, a motorized flat detector C-arm with intraoperative 2D/3D capabilities, integrated optical cameras for augmented reality navigation, and noninvasive patient motion tracking. Two neurosurgeons placed 94 pedicle screws in the thoracic spine of four cadavers using ARSN on one side of the spine (47 screws) and free-hand technique on the contralateral side. X-ray fluoroscopy was not used for either technique. Four independent reviewers assessed the postoperative scans, using the Gertzbein grading. Morphometric measurements of the pedicles axial and sagittal widths and angles, as well as the vertebrae axial and sagittal rotations were performed to identify risk factors for breaches. ARSN was feasible and superior to free-hand technique with respect to overall accuracy (85% vs. 64%, P dimensions, except for vertebral body axial rotation, were risk factors for larger breaches when performed with the free-hand method. ARSN without fluoroscopy was feasible and demonstrated higher accuracy than free-hand technique for thoracic pedicle screw placement. N/A.

  18. Progress in high index contrast integrated optics

    NARCIS (Netherlands)

    Baets, R.G.F.; Bienstman, P.; Bogaerts, W.; Brouckaert, J.; De Backere, P.; Dumon, P.; Roelkens, G.; Scheerlinck, S.; Smit, M.K.; Taillaert, D.; Van Campenhout, J.; Van Laere, F.; Thourhout, Van D.

    2007-01-01

    A large fraction of the recent innovation in integrated optics is enabled by the use of high index contrast structures and devices. The strong confinement achievable in such devices allows for dramatic performance benefits and downscaling. In this paper the progress in this field is reviewed.

  19. An Integrated Reverse Engineering Approach for Accuracy Control of Free-Form Objects

    Directory of Open Access Journals (Sweden)

    Pathak Vimal Kumar

    2016-12-01

    Full Text Available Computer-aided tools help in shortening and eradicating numerous repetitive tasks that reduces the gap between digital model and actual product. Use of these tools assists in realizing free-form objects such as custom fit products as described by a stringent interaction with the human body. Development of such a model presents a challenging situation for reverse engineering (RE which is not analogous with the requirement for generating simple geometric models. Hence, an alternating way of producing more accurate three-dimensional models is proposed. For creating accurate 3D models, point clouds are processed through filtering, segmentation, mesh smoothing and surface generation. These processes help in converting the initial unorganized point data into a 3D digital model and simultaneously influence the quality of model. This study provides an optimum balance for the best accuracy obtainable with maximum allowable deviation to lessen computer handling and processing time. A realistic non trivial case study of free-form prosthetic socket is considered. The accuracy obtained for the developed model is acceptable for the use in medical applications and FEM analysis.

  20. Identification and delineation of areas flood hazard using high accuracy of DEM data

    Science.gov (United States)

    Riadi, B.; Barus, B.; Widiatmaka; Yanuar, M. J. P.; Pramudya, B.

    2018-05-01

    Flood incidents that often occur in Karawang regency need to be mitigated. These expectations exist on technologies that can predict, anticipate and reduce disaster risks. Flood modeling techniques using Digital Elevation Model (DEM) data can be applied in mitigation activities. High accuracy DEM data used in modeling, will result in better flooding flood models. The result of high accuracy DEM data processing will yield information about surface morphology which can be used to identify indication of flood hazard area. The purpose of this study was to identify and describe flood hazard areas by identifying wetland areas using DEM data and Landsat-8 images. TerraSAR-X high-resolution data is used to detect wetlands from landscapes, while land cover is identified by Landsat image data. The Topography Wetness Index (TWI) method is used to detect and identify wetland areas with basic DEM data, while for land cover analysis using Tasseled Cap Transformation (TCT) method. The result of TWI modeling yields information about potential land of flood. Overlay TWI map with land cover map that produces information that in Karawang regency the most vulnerable areas occur flooding in rice fields. The spatial accuracy of the flood hazard area in this study was 87%.

  1. Accuracy of Estimating Highly Eccentric Binary Black Hole Parameters with Gravitational-wave Detections

    Science.gov (United States)

    Gondán, László; Kocsis, Bence; Raffai, Péter; Frei, Zsolt

    2018-03-01

    Mergers of stellar-mass black holes on highly eccentric orbits are among the targets for ground-based gravitational-wave detectors, including LIGO, VIRGO, and KAGRA. These sources may commonly form through gravitational-wave emission in high-velocity dispersion systems or through the secular Kozai–Lidov mechanism in triple systems. Gravitational waves carry information about the binaries’ orbital parameters and source location. Using the Fisher matrix technique, we determine the measurement accuracy with which the LIGO–VIRGO–KAGRA network could measure the source parameters of eccentric binaries using a matched filtering search of the repeated burst and eccentric inspiral phases of the waveform. We account for general relativistic precession and the evolution of the orbital eccentricity and frequency during the inspiral. We find that the signal-to-noise ratio and the parameter measurement accuracy may be significantly higher for eccentric sources than for circular sources. This increase is sensitive to the initial pericenter distance, the initial eccentricity, and the component masses. For instance, compared to a 30 {M}ȯ –30 {M}ȯ non-spinning circular binary, the chirp mass and sky-localization accuracy can improve by a factor of ∼129 (38) and ∼2 (11) for an initially highly eccentric binary assuming an initial pericenter distance of 20 M tot (10 M tot).

  2. High Quality Data for Grid Integration Studies

    Energy Technology Data Exchange (ETDEWEB)

    Clifton, Andrew; Draxl, Caroline; Sengupta, Manajit; Hodge, Bri-Mathias

    2017-01-22

    As variable renewable power penetration levels increase in power systems worldwide, renewable integration studies are crucial to ensure continued economic and reliable operation of the power grid. The existing electric grid infrastructure in the US in particular poses significant limitations on wind power expansion. In this presentation we will shed light on requirements for grid integration studies as far as wind and solar energy are concerned. Because wind and solar plants are strongly impacted by weather, high-resolution and high-quality weather data are required to drive power system simulations. Future data sets will have to push limits of numerical weather prediction to yield these high-resolution data sets, and wind data will have to be time-synchronized with solar data. Current wind and solar integration data sets are presented. The Wind Integration National Dataset (WIND) Toolkit is the largest and most complete grid integration data set publicly available to date. A meteorological data set, wind power production time series, and simulated forecasts created using the Weather Research and Forecasting Model run on a 2-km grid over the continental United States at a 5-min resolution is now publicly available for more than 126,000 land-based and offshore wind power production sites. The National Solar Radiation Database (NSRDB) is a similar high temporal- and spatial resolution database of 18 years of solar resource data for North America and India. The need for high-resolution weather data pushes modeling towards finer scales and closer synchronization. We also present how we anticipate such datasets developing in the future, their benefits, and the challenges with using and disseminating such large amounts of data.

  3. Examining the Influence of Treatment Integrity: Accuracy of Daily Report Card Intervention Implementation and Student Outcome

    Science.gov (United States)

    Vujnovic, Rebecca Kate

    2010-01-01

    Given the deficits associated with ADHD and the significant prevalence, it is important to explore evidence based treatments for ADHD in the classroom and the efficacy with which the classroom teachers implement such interventions. The current investigation is a secondary analysis to investigate the integrity of a Daily Report Card (DRC)…

  4. A Smart High Accuracy Silicon Piezoresistive Pressure Sensor Temperature Compensation System

    Directory of Open Access Journals (Sweden)

    Guanwu Zhou

    2014-07-01

    Full Text Available Theoretical analysis in this paper indicates that the accuracy of a silicon piezoresistive pressure sensor is mainly affected by thermal drift, and varies nonlinearly with the temperature. Here, a smart temperature compensation system to reduce its effect on accuracy is proposed. Firstly, an effective conditioning circuit for signal processing and data acquisition is designed. The hardware to implement the system is fabricated. Then, a program is developed on LabVIEW which incorporates an extreme learning machine (ELM as the calibration algorithm for the pressure drift. The implementation of the algorithm was ported to a micro-control unit (MCU after calibration in the computer. Practical pressure measurement experiments are carried out to verify the system’s performance. The temperature compensation is solved in the interval from −40 to 85 °C. The compensated sensor is aimed at providing pressure measurement in oil-gas pipelines. Compared with other algorithms, ELM acquires higher accuracy and is more suitable for batch compensation because of its higher generalization and faster learning speed. The accuracy, linearity, zero temperature coefficient and sensitivity temperature coefficient of the tested sensor are 2.57% FS, 2.49% FS, 8.1 × 10−5/°C and 29.5 × 10−5/°C before compensation, and are improved to 0.13%FS, 0.15%FS, 1.17 × 10−5/°C and 2.1 × 10−5/°C respectively, after compensation. The experimental results demonstrate that the proposed system is valid for the temperature compensation and high accuracy requirement of the sensor.

  5. Optical System Error Analysis and Calibration Method of High-Accuracy Star Trackers

    Directory of Open Access Journals (Sweden)

    Zheng You

    2013-04-01

    Full Text Available The star tracker is a high-accuracy attitude measurement device widely used in spacecraft. Its performance depends largely on the precision of the optical system parameters. Therefore, the analysis of the optical system parameter errors and a precise calibration model are crucial to the accuracy of the star tracker. Research in this field is relatively lacking a systematic and universal analysis up to now. This paper proposes in detail an approach for the synthetic error analysis of the star tracker, without the complicated theoretical derivation. This approach can determine the error propagation relationship of the star tracker, and can build intuitively and systematically an error model. The analysis results can be used as a foundation and a guide for the optical design, calibration, and compensation of the star tracker. A calibration experiment is designed and conducted. Excellent calibration results are achieved based on the calibration model. To summarize, the error analysis approach and the calibration method are proved to be adequate and precise, and could provide an important guarantee for the design, manufacture, and measurement of high-accuracy star trackers.

  6. Optical system error analysis and calibration method of high-accuracy star trackers.

    Science.gov (United States)

    Sun, Ting; Xing, Fei; You, Zheng

    2013-04-08

    The star tracker is a high-accuracy attitude measurement device widely used in spacecraft. Its performance depends largely on the precision of the optical system parameters. Therefore, the analysis of the optical system parameter errors and a precise calibration model are crucial to the accuracy of the star tracker. Research in this field is relatively lacking a systematic and universal analysis up to now. This paper proposes in detail an approach for the synthetic error analysis of the star tracker, without the complicated theoretical derivation. This approach can determine the error propagation relationship of the star tracker, and can build intuitively and systematically an error model. The analysis results can be used as a foundation and a guide for the optical design, calibration, and compensation of the star tracker. A calibration experiment is designed and conducted. Excellent calibration results are achieved based on the calibration model. To summarize, the error analysis approach and the calibration method are proved to be adequate and precise, and could provide an important guarantee for the design, manufacture, and measurement of high-accuracy star trackers.

  7. High-accuracy determination of the neutron flux at n{sub T}OF

    Energy Technology Data Exchange (ETDEWEB)

    Barbagallo, M.; Colonna, N.; Mastromarco, M.; Meaze, M.; Tagliente, G.; Variale, V. [Sezione di Bari, INFN, Bari (Italy); Guerrero, C.; Andriamonje, S.; Boccone, V.; Brugger, M.; Calviani, M.; Cerutti, F.; Chin, M.; Ferrari, A.; Kadi, Y.; Losito, R.; Versaci, R.; Vlachoudis, V. [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Tsinganis, A. [European Organization for Nuclear Research (CERN), Geneva (Switzerland); National Technical University of Athens (NTUA), Athens (Greece); Tarrio, D.; Duran, I.; Leal-Cidoncha, E.; Paradela, C. [Universidade de Santiago de Compostela, Santiago (Spain); Altstadt, S.; Goebel, K.; Langer, C.; Reifarth, R.; Schmidt, S.; Weigand, M. [Johann-Wolfgang-Goethe Universitaet, Frankfurt (Germany); Andrzejewski, J.; Marganiec, J.; Perkowski, J. [Uniwersytet Lodzki, Lodz (Poland); Audouin, L.; Leong, L.S.; Tassan-Got, L. [Centre National de la Recherche Scientifique/IN2P3 - IPN, Orsay (France); Becares, V.; Cano-Ott, D.; Garcia, A.R.; Gonzalez-Romero, E.; Martinez, T.; Mendoza, E. [Centro de Investigaciones Energeticas Medioambientales y Tecnologicas (CIEMAT), Madrid (Spain); Becvar, F.; Krticka, M.; Kroll, J.; Valenta, S. [Charles University, Prague (Czech Republic); Belloni, F.; Fraval, K.; Gunsing, F.; Lampoudis, C.; Papaevangelou, T. [Commissariata l' Energie Atomique (CEA) Saclay - Irfu, Gif-sur-Yvette (France); Berthoumieux, E.; Chiaveri, E. [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Commissariata l' Energie Atomique (CEA) Saclay - Irfu, Gif-sur-Yvette (France); Billowes, J.; Ware, T.; Wright, T. [University of Manchester, Manchester (United Kingdom); Bosnar, D.; Zugec, P. [University of Zagreb, Department of Physics, Faculty of Science, Zagreb (Croatia); Calvino, F.; Cortes, G.; Gomez-Hornillos, M.B.; Riego, A. [Universitat Politecnica de Catalunya, Barcelona (Spain); Carrapico, C.; Goncalves, I.F.; Sarmento, R.; Vaz, P. [Universidade Tecnica de Lisboa, Instituto Tecnologico e Nuclear, Instituto Superior Tecnico, Lisboa (Portugal); Cortes-Giraldo, M.A.; Praena, J.; Quesada, J.M.; Sabate-Gilarte, M. [Universidad de Sevilla, Sevilla (Spain); Diakaki, M.; Karadimos, D.; Kokkoris, M.; Vlastou, R. [National Technical University of Athens (NTUA), Athens (Greece); Domingo-Pardo, C.; Giubrone, G.; Tain, J.L. [CSIC-Universidad de Valencia, Instituto de Fisica Corpuscular, Valencia (Spain); Dressler, R.; Kivel, N.; Schumann, D.; Steinegger, P. [Paul Scherrer Institut, Villigen PSI (Switzerland); Dzysiuk, N.; Mastinu, P.F. [Laboratori Nazionali di Legnaro, INFN, Rome (Italy); Eleftheriadis, C.; Manousos, A. [Aristotle University of Thessaloniki, Thessaloniki (Greece); Ganesan, S.; Gurusamy, P.; Saxena, A. [Bhabha Atomic Research Centre (BARC), Mumbai (IN); Griesmayer, E.; Jericha, E.; Leeb, H. [Technische Universitaet Wien, Atominstitut, Wien (AT); Hernandez-Prieto, A. [European Organization for Nuclear Research (CERN), Geneva (CH); Universitat Politecnica de Catalunya, Barcelona (ES); Jenkins, D.G.; Vermeulen, M.J. [University of York, Heslington, York (GB); Kaeppeler, F. [Institut fuer Kernphysik, Karlsruhe Institute of Technology, Campus Nord, Karlsruhe (DE); Koehler, P. [Oak Ridge National Laboratory (ORNL), Oak Ridge (US); Lederer, C. [Johann-Wolfgang-Goethe Universitaet, Frankfurt (DE); University of Vienna, Faculty of Physics, Vienna (AT); Massimi, C.; Mingrone, F.; Vannini, G. [Universita di Bologna (IT); INFN, Sezione di Bologna, Dipartimento di Fisica, Bologna (IT); Mengoni, A.; Ventura, A. [Agenzia nazionale per le nuove tecnologie, l' energia e lo sviluppo economico sostenibile (ENEA), Bologna (IT); Milazzo, P.M. [Sezione di Trieste, INFN, Trieste (IT); Mirea, M. [Horia Hulubei National Institute of Physics and Nuclear Engineering - IFIN HH, Bucharest - Magurele (RO); Mondalaers, W.; Plompen, A.; Schillebeeckx, P. [Institute for Reference Materials and Measurements, European Commission JRC, Geel (BE); Pavlik, A.; Wallner, A. [University of Vienna, Faculty of Physics, Vienna (AT); Rauscher, T. [University of Basel, Department of Physics and Astronomy, Basel (CH); Roman, F. [European Organization for Nuclear Research (CERN), Geneva (CH); Horia Hulubei National Institute of Physics and Nuclear Engineering - IFIN HH, Bucharest - Magurele (RO); Rubbia, C. [European Organization for Nuclear Research (CERN), Geneva (CH); Laboratori Nazionali del Gran Sasso dell' INFN, Assergi (AQ) (IT); Weiss, C. [European Organization for Nuclear Research (CERN), Geneva (CH); Johann-Wolfgang-Goethe Universitaet, Frankfurt (DE)

    2013-12-15

    The neutron flux of the n{sub T}OF facility at CERN was measured, after installation of the new spallation target, with four different systems based on three neutron-converting reactions, which represent accepted cross sections standards in different energy regions. A careful comparison and combination of the different measurements allowed us to reach an unprecedented accuracy on the energy dependence of the neutron flux in the very wide range (thermal to 1 GeV) that characterizes the n{sub T}OF neutron beam. This is a pre-requisite for the high accuracy of cross section measurements at n{sub T}OF. An unexpected anomaly in the neutron-induced fission cross section of {sup 235}U is observed in the energy region between 10 and 30keV, hinting at a possible overestimation of this important cross section, well above currently assigned uncertainties. (orig.)

  8. Fission product model for BWR analysis with improved accuracy in high burnup

    International Nuclear Information System (INIS)

    Ikehara, Tadashi; Yamamoto, Munenari; Ando, Yoshihira

    1998-01-01

    A new fission product (FP) chain model has been studied to be used in a BWR lattice calculation. In attempting to establish the model, two requirements, i.e. the accuracy in predicting burnup reactivity and the easiness in practical application, are simultaneously considered. The resultant FP model consists of 81 explicit FP nuclides and two lumped pseudo nuclides having the absorption cross sections independent of burnup history and fuel composition. For the verification, extensive numerical tests covering over a wide range of operational conditions and fuel compositions have been carried out. The results indicate that the estimated errors in burnup reactivity are within 0.1%Δk for exposures up to 100GWd/t. It is concluded that the present model can offer a high degree of accuracy for FP representation in BWR lattice calculation. (author)

  9. High Accuracy Attitude Control System Design for Satellite with Flexible Appendages

    Directory of Open Access Journals (Sweden)

    Wenya Zhou

    2014-01-01

    Full Text Available In order to realize the high accuracy attitude control of satellite with flexible appendages, attitude control system consisting of the controller and structural filter was designed. When the low order vibration frequency of flexible appendages is approximating the bandwidth of attitude control system, the vibration signal will enter the control system through measurement device to bring impact on the accuracy or even the stability. In order to reduce the impact of vibration of appendages on the attitude control system, the structural filter is designed in terms of rejecting the vibration of flexible appendages. Considering the potential problem of in-orbit frequency variation of the flexible appendages, the design method for the adaptive notch filter is proposed based on the in-orbit identification technology. Finally, the simulation results are given to demonstrate the feasibility and effectiveness of the proposed design techniques.

  10. High-accuracy defect sizing for CRDM penetration adapters using the ultrasonic TOFD technique

    International Nuclear Information System (INIS)

    Atkinson, I.

    1995-01-01

    Ultrasonic time-of-flight diffraction (TOFD) is the preferred technique for critical sizing of throughwall orientated defects in a wide range of components, primarily because it is intrinsically more accurate than amplitude-based techniques. For the same reason, TOFD is the preferred technique for sizing the cracks in control rod drive mechanism (CRDM) penetration adapters, which have been the subject of much recent attention. Once the considerable problem of restricted access for the UT probes has been overcome, this inspection lends itself to very high accuracy defect sizing using TOFD. In qualification trials under industrial conditions, depth sizing to an accuracy of ≤ 0.5 mm has been routinely achieved throughout the full wall thickness (16 mm) of the penetration adapters, using only a single probe pair and without recourse to signal processing. (author)

  11. Highly integrated electronics for the star TPC

    Energy Technology Data Exchange (ETDEWEB)

    Arthur, A.A.; Bieser, F.; Hearn, W.; Kleinfelder, S.; Merrick, T.; Millaud, J.; Noggle, T.; Rai, G.; Ritter, H.G.; Wieman, H. [Lawrence Berkeley Laboratory, CA (United States)

    1991-12-31

    The concept for the STAR TPC front-end electronics is presented and the progress toward the development of a fully integrated solution is described. It is the goal of the R+D program to develop the complete electronics chain for the STAR central TPC detector at RHIC. It is obvious that solutions chosen e.g. for ALEPH are not adequate for the 150000 channels that need to be instrumented for readout. It will be necessary to perform all the signal processing, digitization and multiplexing directly on the detector in order to reduce per channel cost and the amount of cabling necessary to read out the information. We follow the approach chosen by the EOS TPC project, where the readout electronics on the detector consists of an integrated preamplifier, a hybrid shaping amplifier, an integrated switched capacitor array and a highly multiplexed ADC. The STAR electronics will be further integrated so that approximately 16 channels of the preamplifier, the shaper, the analog store and the ADC will be contained in two integrated circuits located directly on the pad plane.

  12. High accuracy of family history of melanoma in Danish melanoma cases

    DEFF Research Database (Denmark)

    Wadt, Karin A W; Drzewiecki, Krzysztof T; Gerdes, Anne-Marie

    2015-01-01

    The incidence of melanoma in Denmark has immensely increased over the last 10 years making Denmark a high risk country for melanoma. In the last two decades multiple public campaigns have sought to increase the awareness of melanoma. Family history of melanoma is a known major risk factor...... but previous studies have shown that self-reported family history of melanoma is highly inaccurate. These studies are 15 years old and we wanted to examine if a higher awareness of melanoma has increased the accuracy of self-reported family history of melanoma. We examined the family history of 181 melanoma...

  13. Automation, Operation, and Data Analysis in the Cryogenic, High Accuracy, Refraction Measuring System (CHARMS)

    Science.gov (United States)

    Frey, Bradley J.; Leviton, Douglas B.

    2005-01-01

    The Cryogenic High Accuracy Refraction Measuring System (CHARMS) at NASA's Goddard Space Flight Center has been enhanced in a number of ways in the last year to allow the system to accurately collect refracted beam deviation readings automatically over a range of temperatures from 15 K to well beyond room temperature with high sampling density in both wavelength and temperature. The engineering details which make this possible are presented. The methods by which the most accurate angular measurements are made and the corresponding data reduction methods used to reduce thousands of observed angles to a handful of refractive index values are also discussed.

  14. High transition temperature superconducting integrated circuit

    International Nuclear Information System (INIS)

    DiIorio, M.S.

    1985-01-01

    This thesis describes the design and fabrication of the first superconducting integrated circuit capable of operating at over 10K. The primary component of the circuit is a dc SQUID (Superconducting QUantum Interference Device) which is extremely sensitive to magnetic fields. The dc SQUID consists of two superconductor-normal metal-superconductor (SNS) Josephson microbridges that are fabricated using a novel step-edge process which permits the use of high transition temperature superconductors. By utilizing electron-beam lithography in conjunction with ion-beam etching, very small microbridges can be produced. Such microbridges lead to high performance dc SQUIDs with products of the critical current and normal resistance reaching 1 mV at 4.2 K. These SQUIDs have been extensively characterized, and exhibit excellent electrical characteristics over a wide temperature range. In order to couple electrical signals into the SQUID in a practical fashion, a planar input coil was integrated for efficient coupling. A process was developed to incorporate the technologically important high transition temperature superconducting materials, Nb-Sn and Nb-Ge, using integrated circuit techniques. The primary obstacles were presented by the metallurgical idiosyncrasies of the various materials, such as the need to deposit the superconductors at elevated temperatures, 800-900 0 C, in order to achieve a high transition temperature

  15. Thermal Stability of Magnetic Compass Sensor for High Accuracy Positioning Applications

    Directory of Open Access Journals (Sweden)

    Van-Tang PHAM

    2015-12-01

    Full Text Available Using magnetic compass sensors in angle measurements have a wide area of application such as positioning, robot, landslide, etc. However, one of the most phenomenal that affects to the accuracy of the magnetic compass sensor is the temperature. This paper presents two thermal stability schemes for improving performance of a magnetic compass sensor. The first scheme uses the feedforward structure to adjust the angle output of the compass sensor adapt to the variation of the temperature. The second scheme increases both the temperature working range and steady error performance of the sensor. In this scheme, we try to keep the temperature of the sensor is stable at the certain value (e.g. 25 oC by using a PID (proportional-integral-derivative controller and a heating/cooling generator. Many experiment scenarios have implemented to confirm the effectivity of these solutions.

  16. High-Accuracy Elevation Data at Large Scales from Airborne Single-Pass SAR Interferometry

    Directory of Open Access Journals (Sweden)

    Guy Jean-Pierre Schumann

    2016-01-01

    Full Text Available Digital elevation models (DEMs are essential data sets for disaster risk management and humanitarian relief services as well as many environmental process models. At present, on the hand, globally available DEMs only meet the basic requirements and for many services and modeling studies are not of high enough spatial resolution and lack accuracy in the vertical. On the other hand, LiDAR-DEMs are of very high spatial resolution and great vertical accuracy but acquisition operations can be very costly for spatial scales larger than a couple of hundred square km and also have severe limitations in wetland areas and under cloudy and rainy conditions. The ideal situation would thus be to have a DEM technology that allows larger spatial coverage than LiDAR but without compromising resolution and vertical accuracy and still performing under some adverse weather conditions and at a reasonable cost. In this paper, we present a novel single pass In-SAR technology for airborne vehicles that is cost-effective and can generate DEMs with a vertical error of around 0.3 m for an average spatial resolution of 3 m. To demonstrate this capability, we compare a sample single-pass In-SAR Ka-band DEM of the California Central Valley from the NASA/JPL airborne GLISTIN-A to a high-resolution LiDAR DEM. We also perform a simple sensitivity analysis to floodplain inundation. Based on the findings of our analysis, we argue that this type of technology can and should be used to replace large regions of globally available lower resolution DEMs, particularly in coastal, delta and floodplain areas where a high number of assets, habitats and lives are at risk from natural disasters. We conclude with a discussion on requirements, advantages and caveats in terms of instrument and data processing.

  17. Foot loading with an ankle-foot orthosis: the accuracy of an integrated physical strain trainer.

    Science.gov (United States)

    Pauser, Johannes; Jendrissek, Andreas; Brem, Matthias; Gelse, Kolja; Swoboda, Bernd; Carl, Hans-Dieter

    2012-07-01

    To investigate the value of a built-in physical strain trainer for the monitoring of partial weight bearing with an ankle-foot orthosis. 12 healthy volunteers were asked to perform three trials. Plantar peak pressure values from normal gait (trial one) were defined as 100% (baseline). The following trials were performed with the Vacoped® dynamic vacuum ankle orthosis worn in a neutral position with full weight bearing (trial two) and a restriction to 10% body weight (BW) (trial three), as monitored with an integrated physical strain trainer. Peak plantar pressure values were obtained using the pedar® X system. Peak pressure values were statistically significantly reduced wearing the Vacoped® shoe with full weight bearing for the hindfoot to 68% of the baseline (normal gait) and for the midfoot and forefoot to 83% and 60%, respectively. Limited weight bearing with 10% BW as controlled by physical strain trainer further reduced plantar peak pressure values for the hindfoot to 19%, for the midfoot to 43% of the baseline and the forefoot to 22% of the baseline. The Vacoped® vacuum ankle orthosis significantly reduces plantar peak pressure. The integrated physical strain trainer seems unsuitable to monitor a limitation to 10% BW adequately for the total foot. The concept of controlling partial weight bearing with the hindfoot-addressing device within the orthosis seems debatable but may be useful when the hindfoot in particular must be off-loaded.

  18. Accuracy of cell calculation methods used for analysis of high conversion light water reactor lattice

    International Nuclear Information System (INIS)

    Jeong, Chang-Joon; Okumura, Keisuke; Ishiguro, Yukio; Tanaka, Ken-ichi

    1990-01-01

    Validation tests were made for the accuracy of cell calculation methods used in analyses of tight lattices of a mixed-oxide (MOX) fuel core in a high conversion light water reactor (HCLWR). A series of cell calculations was carried out for the lattices referred from an international HCLWR benchmark comparison, with emphasis placed on the resonance calculation methods; the NR, IR approximations, the collision probability method with ultra-fine energy group. Verification was also performed for the geometrical modelling; a hexagonal/cylindrical cell, and the boundary condition; mirror/white reflection. In the calculations, important reactor physics parameters, such as the neutron multiplication factor, the conversion ratio and the void coefficient, were evaluated using the above methods for various HCLWR lattices with different moderator to fuel volume ratios, fuel materials and fissile plutonium enrichments. The calculated results were compared with each other, and the accuracy and applicability of each method were clarified by comparison with continuous energy Monte Carlo calculations. It was verified that the accuracy of the IR approximation became worse when the neutron spectrum became harder. It was also concluded that the cylindrical cell model with the white boundary condition was not so suitable for MOX fuelled lattices, as for UO 2 fuelled lattices. (author)

  19. Development of a metallic high integrity container

    International Nuclear Information System (INIS)

    Haelsig, R.T.

    1986-01-01

    Nuclear Packaging, a Pacific Nuclear Company, developed a metallic high integrity container (HIC) for the burial of low level radioactive waste. This class of container has received the most extensive review of any burial container licensed in the United States. It is also the first container that has been licensed to meet the requirements of Nuclear Regulatory Commission Regulations 10CFR61. The design and subsequent review considered 300 years corrosion at a depth of 55 feet with no degradation of container structural integrity. The design also included a technical requirement that the container possess a positive vent that would exclude moisture. The alloy that was selected, allows for significant flexibility in container size and configuration which is essential to accommodating the various waste forms. This allowed the development of containers in various sizes and with a variety of closures, that accommodate the internal dimensions of various shipping shields and help minimize radiation exposure during packaging operations. The material used in the metallic container is high corrosion resistant which reduces the need for strict chemical controls at the waste generating facility. This acts to ease the operational requirements in the treatment of several waste streams. The design result is a family of metallic High Integrity Containers (HIC)s that meet all the performance criteria imposed by the regulations, as well as provide a disposable waste container with good transportation efficiency and minimum operational constraints

  20. Accuracy of High-Resolution Ultrasonography in the Detection of Extensor Tendon Lacerations.

    Science.gov (United States)

    Dezfuli, Bobby; Taljanovic, Mihra S; Melville, David M; Krupinski, Elizabeth A; Sheppard, Joseph E

    2016-02-01

    Lacerations to the extensor mechanism are usually diagnosed clinically. Ultrasound (US) has been a growing diagnostic tool for tendon injuries since the 1990s. To date, there has been no publication establishing the accuracy and reliability of US in the evaluation of extensor mechanism lacerations in the hand. The purpose of this study is to determine the accuracy of US to detect extensor tendon injuries in the hand. Sixteen fingers and 4 thumbs in 4 fresh-frozen and thawed cadaveric hands were used. Sixty-eight 0.5-cm transverse skin lacerations were created. Twenty-seven extensor tendons were sharply transected. The remaining skin lacerations were used as sham dissection controls. One US technologist and one fellowship-trained musculoskeletal radiologist performed real-time dynamic US studies in and out of water bath. A second fellowship trained musculoskeletal radiologist subsequently reviewed the static US images. Dynamic and static US interpretation accuracy was assessed using dissection as "truth." All 27 extensor tendon lacerations and controls were identified correctly with dynamic imaging as either injury models that had a transected extensor tendon or sham controls with intact extensor tendons (sensitivity = 100%, specificity = 100%, positive predictive value = 1.0; all significantly greater than chance). Static imaging had a sensitivity of 85%, specificity of 89%, and accuracy of 88% (all significantly greater than chance). The results of the dynamic real time versus static US imaging were clearly different but did not reach statistical significance. Diagnostic US is a very accurate noninvasive study that can identify extensor mechanism injuries. Clinically suspected cases of acute extensor tendon injury scanned by high-frequency US can aid and/or confirm the diagnosis, with dynamic imaging providing added value compared to static. Ultrasonography, to aid in the diagnosis of extensor mechanism lacerations, can be successfully used in a reliable and

  1. Accuracy assessment of high frequency 3D ultrasound for digital impression-taking of prepared teeth

    Science.gov (United States)

    Heger, Stefan; Vollborn, Thorsten; Tinschert, Joachim; Wolfart, Stefan; Radermacher, Klaus

    2013-03-01

    Silicone based impression-taking of prepared teeth followed by plaster casting is well-established but potentially less reliable, error-prone and inefficient, particularly in combination with emerging techniques like computer aided design and manufacturing (CAD/CAM) of dental prosthesis. Intra-oral optical scanners for digital impression-taking have been introduced but until now some drawbacks still exist. Because optical waves can hardly penetrate liquids or soft-tissues, sub-gingival preparations still need to be uncovered invasively prior to scanning. High frequency ultrasound (HFUS) based micro-scanning has been recently investigated as an alternative to optical intra-oral scanning. Ultrasound is less sensitive against oral fluids and in principal able to penetrate gingiva without invasively exposing of sub-gingival preparations. Nevertheless, spatial resolution as well as digitization accuracy of an ultrasound based micro-scanning system remains a critical parameter because the ultrasound wavelength in water-like media such as gingiva is typically smaller than that of optical waves. In this contribution, the in-vitro accuracy of ultrasound based micro-scanning for tooth geometry reconstruction is being investigated and compared to its extra-oral optical counterpart. In order to increase the spatial resolution of the system, 2nd harmonic frequencies from a mechanically driven focused single element transducer were separated and corresponding 3D surface models were calculated for both fundamentals and 2nd harmonics. Measurements on phantoms, model teeth and human teeth were carried out for evaluation of spatial resolution and surface detection accuracy. Comparison of optical and ultrasound digital impression taking indicate that, in terms of accuracy, ultrasound based tooth digitization can be an alternative for optical impression-taking.

  2. Technical accuracy of a neuronavigation system measured with a high-precision mechanical micromanipulator.

    Science.gov (United States)

    Kaus, M; Steinmeier, R; Sporer, T; Ganslandt, O; Fahlbusch, R

    1997-12-01

    This study was designed to determine and evaluate the different system-inherent sources of erroneous target localization of a light-emitting diode (LED)-based neuronavigation system (StealthStation, Stealth Technologies, Boulder, CO). The localization accuracy was estimated by applying a high-precision mechanical micromanipulator to move and exactly locate (+/- 0.1 micron) the pointer at multiple positions in the physical three-dimensional space. The localization error was evaluated by calculating the spatial distance between the (known) LED positions and the LED coordinates measured by the neuronavigator. The results are based on a study of approximately 280,000 independent coordinate measurements. The maximum localization error detected was 0.55 +/- 0.29 mm, with the z direction (distance to the camera array) being the most erroneous coordinate. Minimum localization error was found at a distance of 1400 mm from the central camera (optimal measurement position). Additional error due to 1) mechanical vibrations of the camera tripod (+/- 0.15 mm) and the reference frame (+/- 0.08 mm) and 2) extrapolation of the pointer tip position from the LED coordinates of at least +/- 0.12 mm were detected, leading to a total technical error of 0.55 +/- 0.64 mm. Based on this technical accuracy analysis, a set of handling recommendations is proposed, leading to an improved localization accuracy. The localization error could be reduced by 0.3 +/- 0.15 mm by correct camera positioning (1400 mm distance) plus 0.15 mm by vibration-eliminating fixation of the camera. Correct handling of the probe during the operation may improve the accuracy by up to 0.1 mm.

  3. Accuracy of Coverage Survey Recall following an Integrated Mass Drug Administration for Lymphatic Filariasis, Schistosomiasis, and Soil-Transmitted Helminthiasis

    Science.gov (United States)

    Budge, Philip J.; Sognikin, Edmond; Akosa, Amanda; Mathieu, Els M.; Deming, Michael

    2016-01-01

    Background Achieving target coverage levels for mass drug administration (MDA) is essential to elimination and control efforts for several neglected tropical diseases (NTD). To ensure program goals are met, coverage reported by drug distributors may be validated through household coverage surveys that rely on respondent recall. This is the first study to assess accuracy in such surveys. Methodology/Principal Findings Recall accuracy was tested in a series of coverage surveys conducted at 1, 6, and 12 months after an integrated MDA in Togo during which three drugs (albendazole, ivermectin, and praziquantel) were distributed. Drug distribution was observed during the MDA to ensure accurate recording of persons treated during the MDA. Information was obtained for 506, 1131, and 947 persons surveyed at 1, 6, and 12 months, respectively. Coverage (defined as the percentage of persons taking at least one of the MDA medications) within these groups was respectively 88.3%, 87.4%, and 80.0%, according to the treatment registers; it was 87.9%, 91.4% and 89.4%, according to survey responses. Concordance between respondents and registers on swallowing at least one pill was >95% at 1 month and >86% at 12 months; the lower concordance at 12 months was more likely due to difficulty matching survey respondents with the year-old treatment register rather than inaccurate responses. Respondents generally distinguished between pills similar in appearance; concordance for recall of which pills were taken was over 80% in each survey. Significance In this population, coverage surveys provided remarkably consistent coverage estimates for up to one year following an integrated MDA. It is not clear if similar consistency will be seen in other settings, however, these data suggest that in some settings coverage surveys might be conducted as much as one year following an MDA without compromising results. This might enable integration of post-MDA coverage measurement into large, multipurpose

  4. Accuracy of Coverage Survey Recall following an Integrated Mass Drug Administration for Lymphatic Filariasis, Schistosomiasis, and Soil-Transmitted Helminthiasis.

    Science.gov (United States)

    Budge, Philip J; Sognikin, Edmond; Akosa, Amanda; Mathieu, Els M; Deming, Michael

    2016-01-01

    Achieving target coverage levels for mass drug administration (MDA) is essential to elimination and control efforts for several neglected tropical diseases (NTD). To ensure program goals are met, coverage reported by drug distributors may be validated through household coverage surveys that rely on respondent recall. This is the first study to assess accuracy in such surveys. Recall accuracy was tested in a series of coverage surveys conducted at 1, 6, and 12 months after an integrated MDA in Togo during which three drugs (albendazole, ivermectin, and praziquantel) were distributed. Drug distribution was observed during the MDA to ensure accurate recording of persons treated during the MDA. Information was obtained for 506, 1131, and 947 persons surveyed at 1, 6, and 12 months, respectively. Coverage (defined as the percentage of persons taking at least one of the MDA medications) within these groups was respectively 88.3%, 87.4%, and 80.0%, according to the treatment registers; it was 87.9%, 91.4% and 89.4%, according to survey responses. Concordance between respondents and registers on swallowing at least one pill was >95% at 1 month and >86% at 12 months; the lower concordance at 12 months was more likely due to difficulty matching survey respondents with the year-old treatment register rather than inaccurate responses. Respondents generally distinguished between pills similar in appearance; concordance for recall of which pills were taken was over 80% in each survey. In this population, coverage surveys provided remarkably consistent coverage estimates for up to one year following an integrated MDA. It is not clear if similar consistency will be seen in other settings, however, these data suggest that in some settings coverage surveys might be conducted as much as one year following an MDA without compromising results. This might enable integration of post-MDA coverage measurement into large, multipurpose, periodic surveys, thereby conserving resources.

  5. Accuracy of Coverage Survey Recall following an Integrated Mass Drug Administration for Lymphatic Filariasis, Schistosomiasis, and Soil-Transmitted Helminthiasis.

    Directory of Open Access Journals (Sweden)

    Philip J Budge

    2016-01-01

    Full Text Available Achieving target coverage levels for mass drug administration (MDA is essential to elimination and control efforts for several neglected tropical diseases (NTD. To ensure program goals are met, coverage reported by drug distributors may be validated through household coverage surveys that rely on respondent recall. This is the first study to assess accuracy in such surveys.Recall accuracy was tested in a series of coverage surveys conducted at 1, 6, and 12 months after an integrated MDA in Togo during which three drugs (albendazole, ivermectin, and praziquantel were distributed. Drug distribution was observed during the MDA to ensure accurate recording of persons treated during the MDA. Information was obtained for 506, 1131, and 947 persons surveyed at 1, 6, and 12 months, respectively. Coverage (defined as the percentage of persons taking at least one of the MDA medications within these groups was respectively 88.3%, 87.4%, and 80.0%, according to the treatment registers; it was 87.9%, 91.4% and 89.4%, according to survey responses. Concordance between respondents and registers on swallowing at least one pill was >95% at 1 month and >86% at 12 months; the lower concordance at 12 months was more likely due to difficulty matching survey respondents with the year-old treatment register rather than inaccurate responses. Respondents generally distinguished between pills similar in appearance; concordance for recall of which pills were taken was over 80% in each survey.In this population, coverage surveys provided remarkably consistent coverage estimates for up to one year following an integrated MDA. It is not clear if similar consistency will be seen in other settings, however, these data suggest that in some settings coverage surveys might be conducted as much as one year following an MDA without compromising results. This might enable integration of post-MDA coverage measurement into large, multipurpose, periodic surveys, thereby conserving

  6. An angle encoder for super-high resolution and super-high accuracy using SelfA

    Science.gov (United States)

    Watanabe, Tsukasa; Kon, Masahito; Nabeshima, Nobuo; Taniguchi, Kayoko

    2014-06-01

    Angular measurement technology at high resolution for applications such as in hard disk drive manufacturing machines, precision measurement equipment and aspherical process machines requires a rotary encoder with high accuracy, high resolution and high response speed. However, a rotary encoder has angular deviation factors during operation due to scale error or installation error. It has been assumed to be impossible to achieve accuracy below 0.1″ in angular measurement or control after the installation onto the rotating axis. Self-calibration (Lu and Trumper 2007 CIRP Ann. 56 499; Kim et al 2011 Proc. MacroScale; Probst 2008 Meas. Sci. Technol. 19 015101; Probst et al Meas. Sci. Technol. 9 1059; Tadashi and Makoto 1993 J. Robot. Mechatronics 5 448; Ralf et al 2006 Meas. Sci. Technol. 17 2811) and cross-calibration (Probst et al 1998 Meas. Sci. Technol. 9 1059; Just et al 2009 Precis. Eng. 33 530; Burnashev 2013 Quantum Electron. 43 130) technologies for a rotary encoder have been actively discussed on the basis of the principle of circular closure. This discussion prompted the development of rotary tables which achieve reliable and high accuracy angular verification. We apply these technologies for the development of a rotary encoder not only to meet the requirement of super-high accuracy but also to meet that of super-high resolution. This paper presents the development of an encoder with 221 = 2097 152 resolutions per rotation (360°), that is, corresponding to a 0.62″ signal period, achieved by the combination of a laser rotary encoder supplied by Magnescale Co., Ltd and a self-calibratable encoder (SelfA) supplied by The National Institute of Advanced Industrial Science & Technology (AIST). In addition, this paper introduces the development of a rotary encoder to guarantee ±0.03″ accuracy at any point of the interpolated signal, with respect to the encoder at the minimum resolution of 233, that is, corresponding to a 0.0015″ signal period after

  7. An angle encoder for super-high resolution and super-high accuracy using SelfA

    International Nuclear Information System (INIS)

    Watanabe, Tsukasa; Kon, Masahito; Nabeshima, Nobuo; Taniguchi, Kayoko

    2014-01-01

    Angular measurement technology at high resolution for applications such as in hard disk drive manufacturing machines, precision measurement equipment and aspherical process machines requires a rotary encoder with high accuracy, high resolution and high response speed. However, a rotary encoder has angular deviation factors during operation due to scale error or installation error. It has been assumed to be impossible to achieve accuracy below 0.1″ in angular measurement or control after the installation onto the rotating axis. Self-calibration (Lu and Trumper 2007 CIRP Ann. 56 499; Kim et al 2011 Proc. MacroScale; Probst 2008 Meas. Sci. Technol. 19 015101; Probst et al Meas. Sci. Technol. 9 1059; Tadashi and Makoto 1993 J. Robot. Mechatronics 5 448; Ralf et al 2006 Meas. Sci. Technol. 17 2811) and cross-calibration (Probst et al 1998 Meas. Sci. Technol. 9 1059; Just et al 2009 Precis. Eng. 33 530; Burnashev 2013 Quantum Electron. 43 130) technologies for a rotary encoder have been actively discussed on the basis of the principle of circular closure. This discussion prompted the development of rotary tables which achieve reliable and high accuracy angular verification. We apply these technologies for the development of a rotary encoder not only to meet the requirement of super-high accuracy but also to meet that of super-high resolution. This paper presents the development of an encoder with 2 21 = 2097 152 resolutions per rotation (360°), that is, corresponding to a 0.62″ signal period, achieved by the combination of a laser rotary encoder supplied by Magnescale Co., Ltd and a self-calibratable encoder (SelfA) supplied by The National Institute of Advanced Industrial Science and Technology (AIST). In addition, this paper introduces the development of a rotary encoder to guarantee ±0.03″ accuracy at any point of the interpolated signal, with respect to the encoder at the minimum resolution of 2 33 , that is, corresponding to a 0.0015″ signal period

  8. Ultra-high accuracy optical testing: creating diffraction-limitedshort-wavelength optical systems

    Energy Technology Data Exchange (ETDEWEB)

    Goldberg, Kenneth A.; Naulleau, Patrick P.; Rekawa, Senajith B.; Denham, Paul E.; Liddle, J. Alexander; Gullikson, Eric M.; Jackson, KeithH.; Anderson, Erik H.; Taylor, John S.; Sommargren, Gary E.; Chapman,Henry N.; Phillion, Donald W.; Johnson, Michael; Barty, Anton; Soufli,Regina; Spiller, Eberhard A.; Walton, Christopher C.; Bajt, Sasa

    2005-08-03

    Since 1993, research in the fabrication of extreme ultraviolet (EUV) optical imaging systems, conducted at Lawrence Berkeley National Laboratory (LBNL) and Lawrence Livermore National Laboratory (LLNL), has produced the highest resolution optical systems ever made. We have pioneered the development of ultra-high-accuracy optical testing and alignment methods, working at extreme ultraviolet wavelengths, and pushing wavefront-measuring interferometry into the 2-20-nm wavelength range (60-600 eV). These coherent measurement techniques, including lateral shearing interferometry and phase-shifting point-diffraction interferometry (PS/PDI) have achieved RMS wavefront measurement accuracies of 0.5-1-{angstrom} and better for primary aberration terms, enabling the creation of diffraction-limited EUV optics. The measurement accuracy is established using careful null-testing procedures, and has been verified repeatedly through high-resolution imaging. We believe these methods are broadly applicable to the advancement of short-wavelength optical systems including space telescopes, microscope objectives, projection lenses, synchrotron beamline optics, diffractive and holographic optics, and more. Measurements have been performed on a tunable undulator beamline at LBNL's Advanced Light Source (ALS), optimized for high coherent flux; although many of these techniques should be adaptable to alternative ultraviolet, EUV, and soft x-ray light sources. To date, we have measured nine prototype all-reflective EUV optical systems with NA values between 0.08 and 0.30 (f/6.25 to f/1.67). These projection-imaging lenses were created for the semiconductor industry's advanced research in EUV photolithography, a technology slated for introduction in 2009-13. This paper reviews the methods used and our program's accomplishments to date.

  9. Ultra-high accuracy optical testing: creating diffraction-limited short-wavelength optical systems

    International Nuclear Information System (INIS)

    Goldberg, Kenneth A.; Naulleau, Patrick P.; Rekawa, Senajith B.; Denham, Paul E.; Liddle, J. Alexander; Gullikson, Eric M.; Jackson, KeithH.; Anderson, Erik H.; Taylor, John S.; Sommargren, Gary E.; Chapman, Henry N.; Phillion, Donald W.; Johnson, Michael; Barty, Anton; Soufli, Regina; Spiller, Eberhard A.; Walton, Christopher C.; Bajt, Sasa

    2005-01-01

    Since 1993, research in the fabrication of extreme ultraviolet (EUV) optical imaging systems, conducted at Lawrence Berkeley National Laboratory (LBNL) and Lawrence Livermore National Laboratory (LLNL), has produced the highest resolution optical systems ever made. We have pioneered the development of ultra-high-accuracy optical testing and alignment methods, working at extreme ultraviolet wavelengths, and pushing wavefront-measuring interferometry into the 2-20-nm wavelength range (60-600 eV). These coherent measurement techniques, including lateral shearing interferometry and phase-shifting point-diffraction interferometry (PS/PDI) have achieved RMS wavefront measurement accuracies of 0.5-1-(angstrom) and better for primary aberration terms, enabling the creation of diffraction-limited EUV optics. The measurement accuracy is established using careful null-testing procedures, and has been verified repeatedly through high-resolution imaging. We believe these methods are broadly applicable to the advancement of short-wavelength optical systems including space telescopes, microscope objectives, projection lenses, synchrotron beamline optics, diffractive and holographic optics, and more. Measurements have been performed on a tunable undulator beamline at LBNL's Advanced Light Source (ALS), optimized for high coherent flux; although many of these techniques should be adaptable to alternative ultraviolet, EUV, and soft x-ray light sources. To date, we have measured nine prototype all-reflective EUV optical systems with NA values between 0.08 and 0.30 (f/6.25 to f/1.67). These projection-imaging lenses were created for the semiconductor industry's advanced research in EUV photolithography, a technology slated for introduction in 2009-13. This paper reviews the methods used and our program's accomplishments to date

  10. The use of high accuracy NAA for the certification of NIST botanical standard reference materials

    International Nuclear Information System (INIS)

    Becker, D.A.; Greenberg, R.R.; Stone, S.F.

    1992-01-01

    Neutron activation analysis is one of many analytical techniques used at the National Institute of Standards and Technology (NIST) for the certification of NIST Standard Reference Materials (SRMs). NAA competes favorably with all other techniques because of it's unique capabilities for high accuracy even at very low concentrations for many elements. In this paper, instrumental and radiochemical NAA results are described for 25 elements in two new NIST SRMs, SRM 1515 (Apple Leaves) and SRM 1547 (Peach Leaves), and are compared to the certified values for 19 elements in these two new botanical reference materials. (author) 7 refs.; 4 tabs

  11. High-accuracy critical exponents for O(N) hierarchical 3D sigma models

    International Nuclear Information System (INIS)

    Godina, J. J.; Li, L.; Meurice, Y.; Oktay, M. B.

    2006-01-01

    The critical exponent γ and its subleading exponent Δ in the 3D O(N) Dyson's hierarchical model for N up to 20 are calculated with high accuracy. We calculate the critical temperatures for the measure δ(φ-vector.φ-vector-1). We extract the first coefficients of the 1/N expansion from our numerical data. We show that the leading and subleading exponents agree with Polchinski equation and the equivalent Litim equation, in the local potential approximation, with at least 4 significant digits

  12. High-accuracy mass determination of unstable nuclei with a Penning trap mass spectrometer

    CERN Multimedia

    2002-01-01

    The mass of a nucleus is its most fundamental property. A systematic study of nuclear masses as a function of neutron and proton number allows the observation of collective and single-particle effects in nuclear structure. Accurate mass data are the most basic test of nuclear models and are essential for their improvement. This is especially important for the astrophysical study of nuclear synthesis. In order to achieve the required high accuracy, the mass of ions captured in a Penning trap is determined via their cyclotron frequency $ \

  13. A variational nodal diffusion method of high accuracy; Varijaciona nodalna difuziona metoda visoke tachnosti

    Energy Technology Data Exchange (ETDEWEB)

    Tomasevic, Dj; Altiparmarkov, D [Institut za Nuklearne Nauke Boris Kidric, Belgrade (Yugoslavia)

    1988-07-01

    A variational nodal diffusion method with accurate treatment of transverse leakage shape is developed and presented in this paper. Using Legendre expansion in transverse coordinates higher order quasi-one-dimensional nodal equations are formulated. Numerical solution has been carried out using analytical solutions in alternating directions assuming Legendre expansion of the RHS term. The method has been tested against 2D and 3D IAEA benchmark problem, as well as 2D CANDU benchmark problem. The results are highly accurate. The first order approximation yields to the same order of accuracy as the standard nodal methods with quadratic leakage approximation, while the second order reaches reference solution. (author)

  14. A new ultra-high-accuracy angle generator: current status and future direction

    Science.gov (United States)

    Guertin, Christian F.; Geckeler, Ralf D.

    2017-09-01

    Lack of an extreme high-accuracy angular positioning device available in the United States has left a gap in industrial and scientific efforts conducted there, requiring certain user groups to undertake time-consuming work with overseas laboratories. Specifically, in x-ray mirror metrology the global research community is advancing the state-of-the-art to unprecedented levels. We aim to fill this U.S. gap by developing a versatile high-accuracy angle generator as a part of the national metrology tool set for x-ray mirror metrology and other important industries. Using an established calibration technique to measure the errors of the encoder scale graduations for full-rotation rotary encoders, we implemented an optimized arrangement of sensors positioned to minimize propagation of calibration errors. Our initial feasibility research shows that upon scaling to a full prototype and including additional calibration techniques we can expect to achieve uncertainties at the level of 0.01 arcsec (50 nrad) or better and offer the immense advantage of a highly automatable and customizable product to the commercial market.

  15. Conductus makes high-Tc integrated circuit

    International Nuclear Information System (INIS)

    Anon.

    1991-01-01

    This paper reports that researchers at Conductus have successfully demonstrated what the company says is the world's first integrated circuit containing active devices made from high-temperature superconductors. The circuit is a SQUID magnetometer made from seven layers of material: three layers of yttrium-barium-copper oxide, two layers of insulating material, a seed layer to create grain boundaries for the Josephson junctions, and a layer of silver for making electrical contact to the device. The chip also contains vias, or pathways that make a superconducting contact between the superconducting layers otherwise separated by insulators. Conductus had previously announced the development of a SQUID magnetometer that featured a SQUID sensor and a flux transformer manufactured on separate chips. What makes this achievement important is that the company was able to put both components on the same chip, thus creating a simple integrated circuit on a single chip. This is still a long way from conventional semiconductor technology, with as many as a million components per chip, or even the sophisticated low-Tc superconducting chips made by the Japanese, but the SQUID magnetometer demonstrates all the elements and techniques necessary to build more complex high-temperature superconductor integrated circuits, making this an important first step

  16. High Accuracy, Miniature Pressure Sensor for Very High Temperatures, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — SiWave proposes to develop a compact, low-cost MEMS-based pressure sensor for very high temperatures and low pressures in hypersonic wind tunnels. Most currently...

  17. Integrated High Resolution Monitoring of Mediterranean vegetation

    Science.gov (United States)

    Cesaraccio, Carla; Piga, Alessandra; Ventura, Andrea; Arca, Angelo; Duce, Pierpaolo; Mereu, Simone

    2017-04-01

    The study of the vegetation features in a complex and highly vulnerable ecosystems, such as Mediterranean maquis, leads to the need of using continuous monitoring systems at high spatial and temporal resolution, for a better interpretation of the mechanisms of phenological and eco-physiological processes. Near-surface remote sensing techniques are used to quantify, at high temporal resolution, and with a certain degree of spatial integration, the seasonal variations of the surface optical and radiometric properties. In recent decades, the design and implementation of global monitoring networks involved the use of non-destructive and/or cheaper approaches such as (i) continuous surface fluxes measurement stations, (ii) phenological observation networks, and (iii) measurement of temporal and spatial variations of the vegetation spectral properties. In this work preliminary results from the ECO-SCALE (Integrated High Resolution Monitoring of Mediterranean vegetation) project are reported. The project was manly aimed to develop an integrated system for environmental monitoring based on digital photography, hyperspectral radiometry , and micrometeorological techniques during three years of experimentation (2013-2016) in a Mediterranean site of Italy (Capo Caccia, Alghero). The main results concerned the analysis of chromatic coordinates indices from digital images, to characterized the phenological patterns for typical shrubland species, determining start and duration of the growing season, and the physiological status in relation to different environmental drought conditions; then the seasonal patterns of canopy phenology, was compared to NEE (Net Ecosystem Exchange) patterns, showing similarities. However, maximum values of NEE and ER (Ecosystem respiration), and short term variation, seemed mainly tuned by inter annual pattern of meteorological variables, in particular of temperature recorded in the months preceding the vegetation green-up. Finally, green signals

  18. Design of high performance mechatronics high-tech functionality by multidisciplinary system integration

    CERN Document Server

    Munnig Schmidt, R; Rankers, A

    2014-01-01

    Since they entered our world around the middle of the 20th century, the application of mechatronics has enhanced our lives with functionality based on the integration of electronics, control systems and electric drives.This book deals with the special class of mechatronics that has enabled the exceptional levels of accuracy and speed of high-tech equipment applied in the semiconductor industry, realising the continuous shrink in detailing of micro-electronics and MEMS.As well as the more frequently presented standard subjects of dynamics, motion control, electronics and electromechanics, this

  19. The design of high performance mechatronics high-tech functionality by multidisciplinary system integration

    CERN Document Server

    Munnig Schmidt, R; van Eijk, J

    2011-01-01

    Since they entered our world around the middle of the 20th century, the application of mechatronics has enhanced our lives with functionality based on the integration of electronics, control systems and electric drives. This book deals with the special class of mechatronics that has enabled the exceptional levels of accuracy and speed of high-tech equipment applied in the semiconductor industry, realising the continuous shrink in detailing of micro-electronics and MEMS. As well as the more frequently presented standard subjects of dynamics, motion control, electronics and electromechanics, thi

  20. NiftyPET: a High-throughput Software Platform for High Quantitative Accuracy and Precision PET Imaging and Analysis.

    Science.gov (United States)

    Markiewicz, Pawel J; Ehrhardt, Matthias J; Erlandsson, Kjell; Noonan, Philip J; Barnes, Anna; Schott, Jonathan M; Atkinson, David; Arridge, Simon R; Hutton, Brian F; Ourselin, Sebastien

    2018-01-01

    We present a standalone, scalable and high-throughput software platform for PET image reconstruction and analysis. We focus on high fidelity modelling of the acquisition processes to provide high accuracy and precision quantitative imaging, especially for large axial field of view scanners. All the core routines are implemented using parallel computing available from within the Python package NiftyPET, enabling easy access, manipulation and visualisation of data at any processing stage. The pipeline of the platform starts from MR and raw PET input data and is divided into the following processing stages: (1) list-mode data processing; (2) accurate attenuation coefficient map generation; (3) detector normalisation; (4) exact forward and back projection between sinogram and image space; (5) estimation of reduced-variance random events; (6) high accuracy fully 3D estimation of scatter events; (7) voxel-based partial volume correction; (8) region- and voxel-level image analysis. We demonstrate the advantages of this platform using an amyloid brain scan where all the processing is executed from a single and uniform computational environment in Python. The high accuracy acquisition modelling is achieved through span-1 (no axial compression) ray tracing for true, random and scatter events. Furthermore, the platform offers uncertainty estimation of any image derived statistic to facilitate robust tracking of subtle physiological changes in longitudinal studies. The platform also supports the development of new reconstruction and analysis algorithms through restricting the axial field of view to any set of rings covering a region of interest and thus performing fully 3D reconstruction and corrections using real data significantly faster. All the software is available as open source with the accompanying wiki-page and test data.

  1. High-precision numerical integration of equations in dynamics

    Science.gov (United States)

    Alesova, I. M.; Babadzanjanz, L. K.; Pototskaya, I. Yu.; Pupysheva, Yu. Yu.; Saakyan, A. T.

    2018-05-01

    An important requirement for the process of solving differential equations in Dynamics, such as the equations of the motion of celestial bodies and, in particular, the motion of cosmic robotic systems is high accuracy at large time intervals. One of effective tools for obtaining such solutions is the Taylor series method. In this connection, we note that it is very advantageous to reduce the given equations of Dynamics to systems with polynomial (in unknowns) right-hand sides. This allows us to obtain effective algorithms for finding the Taylor coefficients, a priori error estimates at each step of integration, and an optimal choice of the order of the approximation used. In the paper, these questions are discussed and appropriate algorithms are considered.

  2. An integrated high performance fastbus slave interface

    International Nuclear Information System (INIS)

    Christiansen, J.; Ljuslin, C.

    1992-01-01

    A high performance Fastbus slave interface ASIC is presented. The Fastbus slave integrated circuit (FASIC) is a programmable device, enabling its direct use in many different applications. The FASIC acts as an interface between Fastbus and a 'standard' processor/memory bus. It can work stand-alone or together with a microprocessor. A set of address mapping windows can map Fastbus addresses to convenient memory addresses and at the same time act as address decoding logic. Data rates of 100 MBytes/s to Fastbus can be obtained using an internal FIFO buffer in the FASIC. (orig.)

  3. A generalized polynomial chaos based ensemble Kalman filter with high accuracy

    International Nuclear Information System (INIS)

    Li Jia; Xiu Dongbin

    2009-01-01

    As one of the most adopted sequential data assimilation methods in many areas, especially those involving complex nonlinear dynamics, the ensemble Kalman filter (EnKF) has been under extensive investigation regarding its properties and efficiency. Compared to other variants of the Kalman filter (KF), EnKF is straightforward to implement, as it employs random ensembles to represent solution states. This, however, introduces sampling errors that affect the accuracy of EnKF in a negative manner. Though sampling errors can be easily reduced by using a large number of samples, in practice this is undesirable as each ensemble member is a solution of the system of state equations and can be time consuming to compute for large-scale problems. In this paper we present an efficient EnKF implementation via generalized polynomial chaos (gPC) expansion. The key ingredients of the proposed approach involve (1) solving the system of stochastic state equations via the gPC methodology to gain efficiency; and (2) sampling the gPC approximation of the stochastic solution with an arbitrarily large number of samples, at virtually no additional computational cost, to drastically reduce the sampling errors. The resulting algorithm thus achieves a high accuracy at reduced computational cost, compared to the classical implementations of EnKF. Numerical examples are provided to verify the convergence property and accuracy improvement of the new algorithm. We also prove that for linear systems with Gaussian noise, the first-order gPC Kalman filter method is equivalent to the exact Kalman filter.

  4. A high accuracy algorithm of displacement measurement for a micro-positioning stage

    Directory of Open Access Journals (Sweden)

    Xiang Zhang

    2017-05-01

    Full Text Available A high accuracy displacement measurement algorithm for a two degrees of freedom compliant precision micro-positioning stage is proposed based on the computer micro-vision technique. The algorithm consists of an integer-pixel and a subpixel matching procedure. Series of simulations are conducted to verify the proposed method. The results show that the proposed algorithm possesses the advantages of high precision and stability, the resolution can attain to 0.01 pixel theoretically. In addition, the consuming time is reduced about 6.7 times compared with the classical normalized cross correlation algorithm. To validate the practical performance of the proposed algorithm, a laser interferometer measurement system (LIMS is built up. The experimental results demonstrate that the algorithm has better adaptability than that of the LIMS.

  5. Prediction of novel pre-microRNAs with high accuracy through boosting and SVM.

    Science.gov (United States)

    Zhang, Yuanwei; Yang, Yifan; Zhang, Huan; Jiang, Xiaohua; Xu, Bo; Xue, Yu; Cao, Yunxia; Zhai, Qian; Zhai, Yong; Xu, Mingqing; Cooke, Howard J; Shi, Qinghua

    2011-05-15

    High-throughput deep-sequencing technology has generated an unprecedented number of expressed short sequence reads, presenting not only an opportunity but also a challenge for prediction of novel microRNAs. To verify the existence of candidate microRNAs, we have to show that these short sequences can be processed from candidate pre-microRNAs. However, it is laborious and time consuming to verify these using existing experimental techniques. Therefore, here, we describe a new method, miRD, which is constructed using two feature selection strategies based on support vector machines (SVMs) and boosting method. It is a high-efficiency tool for novel pre-microRNA prediction with accuracy up to 94.0% among different species. miRD is implemented in PHP/PERL+MySQL+R and can be freely accessed at http://mcg.ustc.edu.cn/rpg/mird/mird.php.

  6. High Accuracy mass Measurement of the very Short-Lived Halo Nuclide $^{11}$Li

    CERN Multimedia

    Le scornet, G

    2002-01-01

    The archetypal halo nuclide $^{11}$Li has now attracted a wealth of experimental and theoretical attention. The most outstanding property of this nuclide, its extended radius that makes it as big as $^{48}$Ca, is highly dependent on the binding energy of the two neutrons forming the halo. New generation experiments using radioactive beams with elastic proton scattering, knock-out and transfer reactions, together with $\\textit{ab initio}$ calculations require the tightening of the constraint on the binding energy. Good metrology also requires confirmation of the sole existing precision result to guard against a possible systematic deviation (or mistake). We propose a high accuracy mass determintation of $^{11}$Li, a particularly challenging task due to its very short half-life of 8.6 ms, but one perfectly suiting the MISTRAL spectrometer, now commissioned at ISOLDE. We request 15 shifts of beam time.

  7. Computer modeling of oil spill trajectories with a high accuracy method

    International Nuclear Information System (INIS)

    Garcia-Martinez, Reinaldo; Flores-Tovar, Henry

    1999-01-01

    This paper proposes a high accuracy numerical method to model oil spill trajectories using a particle-tracking algorithm. The Euler method, used to calculate oil trajectories, can give adequate solutions in most open ocean applications. However, this method may not predict accurate particle trajectories in certain highly non-uniform velocity fields near coastal zones or in river problems. Simple numerical experiments show that the Euler method may also introduce artificial numerical dispersion that could lead to overestimation of spill areas. This article proposes a fourth-order Runge-Kutta method with fourth-order velocity interpolation to calculate oil trajectories that minimise these problems. The algorithm is implemented in the OilTrack model to predict oil trajectories following the 'Nissos Amorgos' oil spill accident that occurred in the Gulf of Venezuela in 1997. Despite lack of adequate field information, model results compare well with observations in the impacted area. (Author)

  8. Treatment accuracy of hypofractionated spine and other highly conformal IMRT treatments

    International Nuclear Information System (INIS)

    Sutherland, B.; Hanlon, P.; Charles, P.

    2011-01-01

    Full text: Spinal cord metastases pose difficult challenges for radiation treatment due to tight dose constraints and a concave PTY. This project aimed to thoroughly test the treatment accuracy of the Eclipse Treatment Planning System (TPS) for highly modulated IMRT treatments, in particular of the thoracic spine, using an Elekta Synergy Linear Accelerator. The increased understanding obtained through different quality assurance techniques allowed recommendations to be made for treatment site commissioning with improved accuracy at the Princess Alexandra Hospital (PAH). Three thoracic spine IMRT plans at the PAH were used for data collection. Complex phantom models were built using CT data, and fields simulated using Monte Carlo modelling. The simulated dose distributions were compared with the TPS using gamma analysis and DYH comparison. High resolution QA was done for all fields using the MatriXX ion chamber array, MapCHECK2 diode array shifted, and the EPlD to determine a procedure for commissioning new treatment sites. Basic spine simulations found the TPS overestimated absorbed dose to bone, however within spinal cord there was good agreement. High resolution QA found the average gamma pass rate of the fields to be 99.1 % for MatriXX, 96.5% for MapCHECK2 shifted and 97.7% for EPlD. Preliminary results indicate agreement between the TPS and delivered dose distributions higher than previously believed for the investigated IMRT plans. The poor resolution of the MatriXX, and normalisation issues with MapCHECK2 leads to probable recommendation of EPlD for future IMRT commissioning due to the high resolution and minimal setup required.

  9. High Accuracy, High Energy He-Erd Analysis of H,C, and T

    International Nuclear Information System (INIS)

    Browning, James F.; Langley, Robert A.; Doyle, Barney L.; Banks, James C.; Wampler, William R.

    1999-01-01

    A new analysis technique using high-energy helium ions for the simultaneous elastic recoil detection of all three hydrogen isotopes in metal hydride systems extending to depths of several microm's is presented. Analysis shows that it is possible to separate each hydrogen isotope in a heavy matrix such as erbium to depths of 5 microm using incident 11.48MeV 4 He 2 ions with a detection system composed of a range foil and ΔE-E telescope detector. Newly measured cross sections for the elastic recoil scattering of 4 He 2 ions from protons and deuterons are presented in the energy range 10 to 11.75 MeV for the laboratory recoil angle of 30degree

  10. PACMAN Project: A New Solution for the High-accuracy Alignment of Accelerator Components

    CERN Document Server

    Mainaud Durand, Helene; Buzio, Marco; Caiazza, Domenico; Catalán Lasheras, Nuria; Cherif, Ahmed; Doytchinov, Iordan; Fuchs, Jean-Frederic; Gaddi, Andrea; Galindo Munoz, Natalia; Gayde, Jean-Christophe; Kamugasa, Solomon; Modena, Michele; Novotny, Peter; Russenschuck, Stephan; Sanz, Claude; Severino, Giordana; Tshilumba, David; Vlachakis, Vasileios; Wendt, Manfred; Zorzetti, Silvia

    2016-01-01

    The beam alignment requirements for the next generation of lepton colliders have become increasingly challenging. As an example, the alignment requirements for the three major collider components of the CLIC linear collider are as follows. Before the first beam circulates, the Beam Position Monitors (BPM), Accelerating Structures (AS)and quadrupoles will have to be aligned up to 10 μm w.r.t. a straight line over 200 m long segments, along the 20 km of linacs. PACMAN is a study on Particle Accelerator Components' Metrology and Alignment to the Nanometre scale. It is an Innovative Doctoral Program, funded by the EU and hosted by CERN, providing high quality training to 10 Early Stage Researchers working towards a PhD thesis. The technical aim of the project is to improve the alignment accuracy of the CLIC components by developing new methods and tools addressing several steps of alignment simultaneously, to gain time and accuracy. The tools and methods developed will be validated on a test bench. This paper pr...

  11. High Accuracy Mass Measurement of the Dripline Nuclides $^{12,14}$Be

    CERN Multimedia

    2002-01-01

    State-of-the art, three-body nuclear models that describe halo nuclides require the binding energy of the halo neutron(s) as a critical input parameter. In the case of $^{14}$Be, the uncertainty of this quantity is currently far too large (130 keV), inhibiting efforts at detailed theoretical description. A high accuracy, direct mass deterlnination of $^{14}$Be (as well as $^{12}$Be to obtain the two-neutron separation energy) is therefore required. The measurement can be performed with the MISTRAL spectrometer, which is presently the only possible solution due to required accuracy (10 keV) and short half-life (4.5 ms). Having achieved a 5 keV uncertainty for the mass of $^{11}$Li (8.6 ms), MISTRAL has proved the feasibility of such measurements. Since the current ISOLDE production rate of $^{14}$Be is only about 10/s, the installation of a beam cooler is underway in order to improve MISTRAL transmission. The projected improvement of an order of magnitude (in each transverse direction) will make this measureme...

  12. Accuracy assessment of NOAA gridded daily reference evapotranspiration for the Texas High Plains

    Science.gov (United States)

    Moorhead, Jerry; Gowda, Prasanna H.; Hobbins, Michael; Senay, Gabriel; Paul, George; Marek, Thomas; Porter, Dana

    2015-01-01

    The National Oceanic and Atmospheric Administration (NOAA) provides daily reference evapotranspiration (ETref) maps for the contiguous United States using climatic data from North American Land Data Assimilation System (NLDAS). This data provides large-scale spatial representation of ETref, which is essential for regional scale water resources management. Data used in the development of NOAA daily ETref maps are derived from observations over surfaces that are different from short (grass — ETos) or tall (alfalfa — ETrs) reference crops, often in nonagricultural settings, which carries an unknown discrepancy between assumed and actual conditions. In this study, NOAA daily ETos and ETrs maps were evaluated for accuracy, using observed data from the Texas High Plains Evapotranspiration (TXHPET) network. Daily ETos, ETrs and the climatic data (air temperature, wind speed, and solar radiation) used for calculating ETref were extracted from the NOAA maps for TXHPET locations and compared against ground measurements on reference grass surfaces. NOAA ETrefmaps generally overestimated the TXHPET observations (1.4 and 2.2 mm/day ETos and ETrs, respectively), which may be attributed to errors in the NLDAS modeled air temperature and wind speed, to which reference ETref is most sensitive. Therefore, a bias correction to NLDAS modeled air temperature and wind speed data, or adjustment to the resulting NOAA ETref, may be needed to improve the accuracy of NOAA ETref maps.

  13. High Accuracy Beam Current Monitor System for CEBAF'S Experimental Hall A

    International Nuclear Information System (INIS)

    J. Denard; A. Saha; G. Lavessiere

    2001-01-01

    CEBAF accelerator delivers continuous wave (CW) electron beams to three experimental Halls. In Hall A, all experiments require continuous, non-invasive current measurements and a few experiments require an absolute accuracy of 0.2 % in the current range from 1 to 180 (micro)A. A Parametric Current Transformer (PCT), manufactured by Bergoz, has an accurate and stable sensitivity of 4 (micro)A/V but its offset drifts at the muA level over time preclude its direct use for continuous measurements. Two cavity monitors are calibrated against the PCT with at least 50 (micro)A of beam current. The calibration procedure suppresses the error due to PCT's offset drifts by turning the beam on and off, which is invasive to the experiment. One of the goals of the system is to minimize the calibration time without compromising the measurement's accuracy. The linearity of the cavity monitors is a critical parameter for transferring the accurate calibration done at high currents over the whole dynamic range. The method for measuring accurately the linearity is described

  14. Medication adherence assessment: high accuracy of the new Ingestible Sensor System in kidney transplants.

    Science.gov (United States)

    Eisenberger, Ute; Wüthrich, Rudolf P; Bock, Andreas; Ambühl, Patrice; Steiger, Jürg; Intondi, Allison; Kuranoff, Susan; Maier, Thomas; Green, Damian; DiCarlo, Lorenzo; Feutren, Gilles; De Geest, Sabina

    2013-08-15

    This open-label single-arm exploratory study evaluated the accuracy of the Ingestible Sensor System (ISS), a novel technology for directly assessing the ingestion of oral medications and treatment adherence. ISS consists of an ingestible event marker (IEM), a microsensor that becomes activated in gastric fluid, and an adhesive personal monitor (APM) that detects IEM activation. In this study, the IEM was combined to enteric-coated mycophenolate sodium (ECMPS). Twenty stable adult kidney transplants received IEM-ECMPS for a mean of 9.2 weeks totaling 1227 cumulative days. Eight patients prematurely discontinued treatment due to ECMPS gastrointestinal symptoms (n=2), skin intolerance to APM (n=2), and insufficient system usability (n=4). Rash or erythema due to APM was reported in 7 (37%) patients, all during the first month of use. No serious or severe adverse events and no rejection episode were reported. IEM detection accuracy was 100% over 34 directly observed ingestions; Taking Adherence was 99.4% over a total of 2824 prescribed IEM-ECMPS ingestions. ISS could detect accurately the ingestion of two IEM-ECMPS capsules taken at the same time (detection rate of 99.3%, n=2376). ISS is a promising new technology that provides highly reliable measurements of intake and timing of intake of drugs that are combined with the IEM.

  15. Combined Scintigraphy and Tumor Marker Analysis Predicts Unfavorable Histopathology of Neuroblastic Tumors with High Accuracy.

    Directory of Open Access Journals (Sweden)

    Wolfgang Peter Fendler

    Full Text Available Our aim was to improve the prediction of unfavorable histopathology (UH in neuroblastic tumors through combined imaging and biochemical parameters.123I-MIBG SPECT and MRI was performed before surgical resection or biopsy in 47 consecutive pediatric patients with neuroblastic tumor. Semi-quantitative tumor-to-liver count-rate ratio (TLCRR, MRI tumor size and margins, urine catecholamine and NSE blood levels of neuron specific enolase (NSE were recorded. Accuracy of single and combined variables for prediction of UH was tested by ROC analysis with Bonferroni correction.34 of 47 patients had UH based on the International Neuroblastoma Pathology Classification (INPC. TLCRR and serum NSE both predicted UH with moderate accuracy. Optimal cut-off for TLCRR was 2.0, resulting in 68% sensitivity and 100% specificity (AUC-ROC 0.86, p < 0.001. Optimal cut-off for NSE was 25.8 ng/ml, resulting in 74% sensitivity and 85% specificity (AUC-ROC 0.81, p = 0.001. Combination of TLCRR/NSE criteria reduced false negative findings from 11/9 to only five, with improved sensitivity and specificity of 85% (AUC-ROC 0.85, p < 0.001.Strong 123I-MIBG uptake and high serum level of NSE were each predictive of UH. Combined analysis of both parameters improved the prediction of UH in patients with neuroblastic tumor. MRI parameters and urine catecholamine levels did not predict UH.

  16. Enhancing the Accuracy of Advanced High Temperature Mechanical Testing through Thermography

    Directory of Open Access Journals (Sweden)

    Jonathan Jones

    2018-03-01

    Full Text Available This paper describes the advantages and enhanced accuracy thermography provides to high temperature mechanical testing. This technique is not only used to monitor, but also to control test specimen temperatures where the infra-red technique enables accurate non-invasive control of rapid thermal cycling for non-metallic materials. Isothermal and dynamic waveforms are employed over a 200–800 °C temperature range to pre-oxidised and coated specimens to assess the capability of the technique. This application shows thermography to be accurate to within ±2 °C of thermocouples, a standardised measurement technique. This work demonstrates the superior visibility of test temperatures previously unobtainable by conventional thermocouples or even more modern pyrometers that thermography can deliver. As a result, the speed and accuracy of thermal profiling, thermal gradient measurements and cold/hot spot identification using the technique has increased significantly to the point where temperature can now be controlled by averaging over a specified area. The increased visibility of specimen temperatures has revealed additional unknown effects such as thermocouple shadowing, preferential crack tip heating within an induction coil, and, fundamental response time of individual measurement techniques which are investigated further.

  17. High accuracy of family history of melanoma in Danish melanoma cases.

    Science.gov (United States)

    Wadt, Karin A W; Drzewiecki, Krzysztof T; Gerdes, Anne-Marie

    2015-12-01

    The incidence of melanoma in Denmark has immensely increased over the last 10 years making Denmark a high risk country for melanoma. In the last two decades multiple public campaigns have sought to increase the awareness of melanoma. Family history of melanoma is a known major risk factor but previous studies have shown that self-reported family history of melanoma is highly inaccurate. These studies are 15 years old and we wanted to examine if a higher awareness of melanoma has increased the accuracy of self-reported family history of melanoma. We examined the family history of 181 melanoma probands who reported 199 cases of melanoma in relatives, of which 135 cases where in first degree relatives. We confirmed the diagnosis of melanoma in 77% of all relatives, and in 83% of first degree relatives. In 181 probands we validated the negative family history of melanoma in 748 first degree relatives and found only 1 case of melanoma which was not reported in a 3 case melanoma family. Melanoma patients in Denmark report family history of melanoma in first and second degree relatives with a high level of accuracy with a true positive predictive value between 77 and 87%. In 99% of probands reporting a negative family history of melanoma in first degree relatives this information is correct. In clinical practice we recommend that melanoma diagnosis in relatives should be verified if possible, but even unverified reported melanoma cases in relatives should be included in the indication of genetic testing and assessment of melanoma risk in the family.

  18. High accuracy Primary Reference gas Mixtures for high-impact greenhouse gases

    Science.gov (United States)

    Nieuwenkamp, Gerard; Zalewska, Ewelina; Pearce-Hill, Ruth; Brewer, Paul; Resner, Kate; Mace, Tatiana; Tarhan, Tanil; Zellweger, Christophe; Mohn, Joachim

    2017-04-01

    Climate change, due to increased man-made emissions of greenhouse gases, poses one of the greatest risks to society worldwide. High-impact greenhouse gases (CO2, CH4 and N2O) and indirect drivers for global warming (e.g. CO) are measured by the global monitoring stations for greenhouse gases, operated and organized by the World Meteorological Organization (WMO). Reference gases for the calibration of analyzers have to meet very challenging low level of measurement uncertainty to comply with the Data Quality Objectives (DQOs) set by the WMO. Within the framework of the European Metrology Research Programme (EMRP), a project to improve the metrology for high-impact greenhouse gases was granted (HIGHGAS, June 2014-May 2017). As a result of the HIGHGAS project, primary reference gas mixtures in cylinders for ambient levels of CO2, CH4, N2O and CO in air have been prepared with unprecedented low uncertainties, typically 3-10 times lower than usually previously achieved by the NMIs. To accomplish these low uncertainties in the reference standards, a number of preparation and analysis steps have been studied and improved. The purity analysis of the parent gases had to be performed with lower detection limits than previously achievable. E.g., to achieve an uncertainty of 2•10-9 mol/mol (absolute) on the amount fraction for N2O, the detection limit for the N2O analysis in the parent gases has to be in the sub nmol/mol domain. Results of an OPO-CRDS analyzer set-up in the 5µm wavelength domain, with a 200•10-12 mol/mol detection limit for N2O, will be presented. The adsorption effects of greenhouse gas components at cylinder surfaces are critical, and have been studied for different cylinder passivation techniques. Results of a two-year stability study will be presented. The fit-for-purpose of the reference materials was studied for possible variation on isotopic composition between the reference material and the sample. Measurement results for a suit of CO2 in air

  19. Demonstrating High-Accuracy Orbital Access Using Open-Source Tools

    Science.gov (United States)

    Gilbertson, Christian; Welch, Bryan

    2017-01-01

    Orbit propagation is fundamental to almost every space-based analysis. Currently, many system analysts use commercial software to predict the future positions of orbiting satellites. This is one of many capabilities that can replicated, with great accuracy, without using expensive, proprietary software. NASAs SCaN (Space Communication and Navigation) Center for Engineering, Networks, Integration, and Communications (SCENIC) project plans to provide its analysis capabilities using a combination of internal and open-source software, allowing for a much greater measure of customization and flexibility, while reducing recurring software license costs. MATLAB and the open-source Orbit Determination Toolbox created by Goddard Space Flight Center (GSFC) were utilized to develop tools with the capability to propagate orbits, perform line-of-sight (LOS) availability analyses, and visualize the results. The developed programs are modular and can be applied for mission planning and viability analysis in a variety of Solar System applications. The tools can perform 2 and N-body orbit propagation, find inter-satellite and satellite to ground station LOS access (accounting for intermediate oblate spheroid body blocking, geometric restrictions of the antenna field-of-view (FOV), and relativistic corrections), and create animations of planetary movement, satellite orbits, and LOS accesses. The code is the basis for SCENICs broad analysis capabilities including dynamic link analysis, dilution-of-precision navigation analysis, and orbital availability calculations.

  20. Evaluation of solitary pulmonary nodules by integrated PET/CT: improved accuracy by FDG uptake pattern and CT findings

    International Nuclear Information System (INIS)

    Joon Young Choi; Kyung Soo Lee; O Jung Kwon; Young Mog Shim; Kyung-Han Lee; Yong Choi; Yearn Seong Choe; Byung-Tae Kim

    2004-01-01

    Objective: FDG PET is useful to differentiate malignancy from benign lesions in the evaluation of solitary pulmonary nodules (SPNs). However, FDG PET showed false positive results in benign inflammatory lesions such as tuberculosis and organizing pneumonia. Furthermore, malignant tumors such as adenocarcinoma (AC) with bronchioloalveolar carcinoma (BAC) type had lower FDG uptake than other cell types of non-small cell lung cancer. We investigated whether FDG uptake pattern and image findings of CT for attenuation correction could improve accuracy for evaluating SPNs over SUV in integrated PET/CT imaging using FDG. Methods: Forty patients (M:F = 23:17, mean age 58.2±9.4 yrs) with non-calcified SPNs (diameter on CT 30 mm, no significant mediastinal node enlargement, no atelectasis) were included. All subjects underwent integrated PET/CT imaging using FDG. One nuclear medicine physician and 1 chest radiologist interpreted the PET and non-contrast CT images for attenuation correction, respectively. On PET images, maximum SUV of SPN was acquired, and FDG uptake pattern was categorized as diffusely increased or heterogeneously increased with upper threshold of window setting adjusted to maximum SUV of each nodule. A radiologist interpreted SPNs as benign or malignant based on CT images with lung and mediastinai window settings blinded to PET findings. Results: On pathological exam, 30 SPNs were confirmed to be malignant (11 AC with non-BAC type, 8 AC with BAC type, 8 squamous cell carcinoma, 1 adenosquamous cell carcinoma, 1 neuroendocrine carcinoma, 1 large cell carcinoma), and 10 were benign (4 tuberculosis, 3 organizing pneumonia, 2 sclerosing pneumocytoma, 1 non-specific inflammation). All 5 nodules with max SUV 7.0 except one with tuberculoma had malignancy. When only nodules with diffusely increased uptake were considered malignant in indeterminate group with max SUV of 4.0 to 7.0, PET could diagnose 5 of 9 malignant nodules with one false positive nodule. In 6 of

  1. Study on the Accuracy Improvement of the Second-Kind Fredholm Integral Equations by Using the Buffa-Christiansen Functions with MLFMA

    Directory of Open Access Journals (Sweden)

    Yue-Qian Wu

    2016-01-01

    Full Text Available Former works show that the accuracy of the second-kind integral equations can be improved dramatically by using the rotated Buffa-Christiansen (BC functions as the testing functions, and sometimes their accuracy can be even better than the first-kind integral equations. When the rotated BC functions are used as the testing functions, the discretization error of the identity operators involved in the second-kind integral equations can be suppressed significantly. However, the sizes of spherical objects which were analyzed are relatively small. Numerical capability of the method of moments (MoM for solving integral equations with the rotated BC functions is severely limited. Hence, the performance of BC functions for accuracy improvement of electrically large objects is not studied. In this paper, the multilevel fast multipole algorithm (MLFMA is employed to accelerate iterative solution of the magnetic-field integral equation (MFIE. Then a series of numerical experiments are performed to study accuracy improvement of MFIE in perfect electric conductor (PEC cases with the rotated BC as testing functions. Numerical results show that the effect of accuracy improvement by using the rotated BC as the testing functions is greatly different with curvilinear or plane triangular elements but falls off when the size of the object is large.

  2. Recent high-accuracy measurements of the 1S0 neutron-neutron scattering length

    International Nuclear Information System (INIS)

    Howell, C.R.; Chen, Q.; Gonzalez Trotter, D.E.; Salinas, F.; Crowell, A.S.; Roper, C.D.; Tornow, W.; Walter, R.L.; Carman, T.S.; Hussein, A.; Gibbs, W.R.; Gibson, B.F.; Morris, C.; Obst, A.; Sterbenz, S.; Whitton, M.; Mertens, G.; Moore, C.F.; Whiteley, C.R.; Pasyuk, E.; Slaus, I.; Tang, H.; Zhou, Z.; Gloeckle, W.; Witala, H.

    2000-01-01

    This paper reports two recent high-accuracy determinations of the 1 S 0 neutron-neutron scattering length, a nn . One was done at the Los Alamos National Laboratory using the π - d capture reaction to produce two neutrons with low relative momentum. The neutron-deuteron (nd) breakup reaction was used in other measurement, which was conducted at the Triangle Universities Nuclear Laboratory. The results from the two determinations were consistent with each other and with previous values obtained using the π - d capture reaction. The value obtained from the nd breakup measurements is a nn = -18.7 ± 0.1 (statistical) ± 0.6 (systematic) fm, and the value from the π - d capture experiment is a nn = -18.50 ± 0.05 ± 0.53 fm. The recommended value is a nn = -18.5 ± 0.3 fm. (author)

  3. High accuracy amplitude and phase measurements based on a double heterodyne architecture

    International Nuclear Information System (INIS)

    Zhao Danyang; Wang Guangwei; Pan Weimin

    2015-01-01

    In the digital low level RF (LLRF) system of a circular (particle) accelerator, the RF field signal is usually down converted to a fixed intermediate frequency (IF). The ratio of IF and sampling frequency determines the processing required, and differs in various LLRF systems. It is generally desirable to design a universally compatible architecture for different IFs with no change to the sampling frequency and algorithm. A new RF detection method based on a double heterodyne architecture for wide IF range has been developed, which achieves the high accuracy requirement of modern LLRF. In this paper, the relation of IF and phase error is systematically analyzed for the first time and verified by experiments. The effects of temperature drift for 16 h IF detection are inhibited by the amplitude and phase calibrations. (authors)

  4. High-accuracy biodistribution analysis of adeno-associated virus variants by double barcode sequencing.

    Science.gov (United States)

    Marsic, Damien; Méndez-Gómez, Héctor R; Zolotukhin, Sergei

    2015-01-01

    Biodistribution analysis is a key step in the evaluation of adeno-associated virus (AAV) capsid variants, whether natural isolates or produced by rational design or directed evolution. Indeed, when screening candidate vectors, accurate knowledge about which tissues are infected and how efficiently is essential. We describe the design, validation, and application of a new vector, pTR-UF50-BC, encoding a bioluminescent protein, a fluorescent protein and a DNA barcode, which can be used to visualize localization of transduction at the organism, organ, tissue, or cellular levels. In addition, by linking capsid variants to different barcoded versions of the vector and amplifying the barcode region from various tissue samples using barcoded primers, biodistribution of viral genomes can be analyzed with high accuracy and efficiency.

  5. Accuracy and high-speed technique for autoprocessing of Young's fringes

    Science.gov (United States)

    Chen, Wenyi; Tan, Yushan

    1991-12-01

    In this paper, an accurate and high-speed method for auto-processing of Young's fringes is proposed. A group of 1-D sampled intensity values along three or more different directions are taken from Young's fringes, and the fringe spacings of each direction are obtained by 1-D FFT respectively. Two directions that have smaller fringe spacing are selected from all directions. The accurate fringe spacings along these two directions are obtained by using orthogonal coherent phase detection technique (OCPD). The actual spacing and angle of Young's fringes, therefore, can be calculated. In this paper, the principle of OCPD is introduced in detail. The accuracy of the method is evaluated theoretically and experimentally.

  6. DEVELOPMENT OF COMPLEXITY, ACCURACY, AND FLUENCY IN HIGH SCHOOL STUDENTS’ WRITTEN FOREIGN LANGUAGE PRODUCTION

    Directory of Open Access Journals (Sweden)

    Bouchaib Benzehaf

    2016-11-01

    Full Text Available The present study aims to longitudinally depict the dynamic and interactive development of Complexity, Accuracy, and Fluency (CAF in multilingual learners’ L2 and L3 writing. The data sources include free writing tasks written in L2 French and L3 English by 45 high school participants over a period of four semesters. CAF dimensions are measured using a variation of Hunt’s T-units (1964. Analysis of the quantitative data obtained suggests that CAF measures develop differently for learners’ L2 French and L3 English. They increase more persistently in L3 English, and they display the characteristics of a dynamic, non-linear system characterized by ups and downs particularly in L2 French. In light of the results, we suggest more and denser longitudinal data to explore the nature of interactions between these dimensions in foreign language development, particularly at the individual level.

  7. Accuracy of thick-walled hollows during piercing on three-high mill

    International Nuclear Information System (INIS)

    Potapov, I.N.; Romantsev, B.A.; Shamanaev, V.I.; Popov, V.A.; Kharitonov, E.A.

    1975-01-01

    The results of investigations are presented concerning the accuracy of geometrical dimensions of thick-walled sleeves produced by piercing on a 100-ton trio screw rolling mill MISiS with three schemes of fixing and centering the rod. The use of a spherical thrust journal for the rod and of a long centering bushing makes it possible to diminish the non-uniformity of the wall thickness of the sleeves by 30-50%. It is established that thick-walled sleeves with accurate geometrical dimensions (nonuniformity of the wall thickness being less than 10%) can be produced if the system sleeve - mandrel - rod is highly rigid and the rod has a two- or three-fold stability margin over the length equal to that of the sleeve being pierced. The process of piercing is expedient to be carried out with increased angles of feed (14-16 deg). Blanks have been made from steel 12Kh1MF

  8. Development of metallic high integrity containers

    International Nuclear Information System (INIS)

    Temus, C.J.; Porter, S.A.; Kent, J.D.; Goetsch, S.D.

    1985-01-01

    This paper presents the development program for metallic high integrity containers (HIC's). The need for a high strength, thin walled HIC became apparent with the implementation of 10 CFR 61 in late 1983. The existing containers that were in use at that time were made of either low strength material (polyethylene) or bulky, heavy material (concrete). Neither of these materials met the need for a high strength, volume and weight efficient container that could survive the deep burial environment of sites such as Hanford, Washington. Various alloys were considered for corrosion resistance for a 300 year life, high strength and toughness, and elastic stability to meet the requirements of 10 CFR 61. The alloy allowed for great flexibility in design to accommodate various waste forms. The containers were developed in various sizes with several different closures designed to minimize operator exposure during the loading operation. These design features provide the industry with efficient, disposable packages for a wide variety of waste forms. The paper describes the analytical methodology and prototype test program. The analytical methods included finite element modeling of the burial conditions, prediction of drop performance,and elastic stability analysis. Prototype testing included leak tests and drop tests at various container orientations from heights of up to 25 feet

  9. Innovative High-Accuracy Lidar Bathymetric Technique for the Frequent Measurement of River Systems

    Science.gov (United States)

    Gisler, A.; Crowley, G.; Thayer, J. P.; Thompson, G. S.; Barton-Grimley, R. A.

    2015-12-01

    Lidar (light detection and ranging) provides absolute depth and topographic mapping capability compared to other remote sensing methods, which is useful for mapping rapidly changing environments such as riverine systems. Effectiveness of current lidar bathymetric systems is limited by the difficulty in unambiguously identifying backscattered lidar signals from the water surface versus the bottom, limiting their depth resolution to 0.3-0.5 m. Additionally these are large, bulky systems that are constrained to expensive aircraft-mounted platforms and use waveform-processing techniques requiring substantial computation time. These restrictions are prohibitive for many potential users. A novel lidar device has been developed that allows for non-contact measurements of water depth down to 1 cm with an accuracy and precision of shallow to deep water allowing for shoreline charting, measuring water volume, mapping bottom topology, and identifying submerged objects. The scalability of the technique opens up the ability for handheld or UAS-mounted lidar bathymetric systems, which provides for potential applications currently unavailable to the community. The high laser pulse repetition rate allows for very fine horizontal resolution while the photon-counting technique permits real-time depth measurement and object detection. The enhanced measurement capability, portability, scalability, and relatively low-cost creates the opportunity to perform frequent high-accuracy monitoring and measuring of aquatic environments which is crucial for understanding how rivers evolve over many timescales. Results from recent campaigns measuring water depth in flowing creeks and murky ponds will be presented which demonstrate that the method is not limited by rough water surfaces and can map underwater topology through moderately turbid water.

  10. Innovative Technique for High-Accuracy Remote Monitoring of Surface Water

    Science.gov (United States)

    Gisler, A.; Barton-Grimley, R. A.; Thayer, J. P.; Crowley, G.

    2016-12-01

    Lidar (light detection and ranging) provides absolute depth and topographic mapping capability compared to other remote sensing methods, which is useful for mapping rapidly changing environments such as riverine systems and agricultural waterways. Effectiveness of current lidar bathymetric systems is limited by the difficulty in unambiguously identifying backscattered lidar signals from the water surface versus the bottom, limiting their depth resolution to 0.3-0.5 m. Additionally these are large, bulky systems that are constrained to expensive aircraft-mounted platforms and use waveform-processing techniques requiring substantial computation time. These restrictions are prohibitive for many potential users. A novel lidar device has been developed that allows for non-contact measurements of water depth down to 1 cm with an accuracy and precision of shallow to deep water allowing for shoreline charting, measuring water volume, mapping bottom topology, and identifying submerged objects. The scalability of the technique opens up the ability for handheld or UAS-mounted lidar bathymetric systems, which provides for potential applications currently unavailable to the community. The high laser pulse repetition rate allows for very fine horizontal resolution while the photon-counting technique permits real-time depth measurement and object detection. The enhanced measurement capability, portability, scalability, and relatively low-cost creates the opportunity to perform frequent high-accuracy monitoring and measuring of aquatic environments which is crucial for monitoring water resources on fast timescales. Results from recent campaigns measuring water depth in flowing creeks and murky ponds will be presented which demonstrate that the method is not limited by rough water surfaces and can map underwater topology through moderately turbid water.

  11. High-accuracy continuous airborne measurements of greenhouse gases (CO2 and CH4) during BARCA

    Science.gov (United States)

    Chen, H.; Winderlich, J.; Gerbig, C.; Hoefer, A.; Rella, C. W.; Crosson, E. R.; van Pelt, A. D.; Steinbach, J.; Kolle, O.; Beck, V.; Daube, B. C.; Gottlieb, E. W.; Chow, V. Y.; Santoni, G. W.; Wofsy, S. C.

    2009-12-01

    High-accuracy continuous measurements of greenhouse gases (CO2 and CH4) during the BARCA (Balanço Atmosférico Regional de Carbono na Amazônia) phase B campaign in Brazil in May 2009 were accomplished using a newly available analyzer based on the cavity ring-down spectroscopy (CRDS) technique. This analyzer was flown without a drying system or any in-flight calibration gases. Water vapor corrections associated with dilution and pressure-broadening effects for CO2 and CH4 were derived from laboratory experiments employing measurements of water vapor by the CRDS analyzer. Before the campaign, the stability of the analyzer was assessed by laboratory tests under simulated flight conditions. During the campaign, a comparison of CO2 measurements between the CRDS analyzer and a nondispersive infrared (NDIR) analyzer on board the same aircraft showed a mean difference of 0.22±0.09 ppm for all flights over the Amazon rain forest. At the end of the campaign, CO2 concentrations of the synthetic calibration gases used by the NDIR analyzer were determined by the CRDS analyzer. After correcting for the isotope and the pressure-broadening effects that resulted from changes of the composition of synthetic vs. ambient air, and applying those concentrations as calibrated values of the calibration gases to reprocess the CO2 measurements made by the NDIR, the mean difference between the CRDS and the NDIR during BARCA was reduced to 0.05±0.09 ppm, with the mean standard deviation of 0.23±0.05 ppm. The results clearly show that the CRDS is sufficiently stable to be used in flight without drying the air or calibrating in flight and the water corrections are fully adequate for high-accuracy continuous airborne measurements of CO2 and CH4.

  12. High-accuracy self-mixing interferometer based on single high-order orthogonally polarized feedback effects.

    Science.gov (United States)

    Zeng, Zhaoli; Qu, Xueming; Tan, Yidong; Tan, Runtao; Zhang, Shulian

    2015-06-29

    A simple and high-accuracy self-mixing interferometer based on single high-order orthogonally polarized feedback effects is presented. The single high-order feedback effect is realized when dual-frequency laser reflects numerous times in a Fabry-Perot cavity and then goes back to the laser resonator along the same route. In this case, two orthogonally polarized feedback fringes with nanoscale resolution are obtained. This self-mixing interferometer has the advantages of higher sensitivity to weak signal than that of conventional interferometer. In addition, two orthogonally polarized fringes are useful for discriminating the moving direction of measured object. The experiment of measuring 2.5nm step is conducted, which shows a great potential in nanometrology.

  13. An integrated high performance Fastbus slave interface

    International Nuclear Information System (INIS)

    Christiansen, J.; Ljuslin, C.

    1993-01-01

    A high performance CMOS Fastbus slave interface ASIC (Application Specific Integrated Circuit) supporting all addressing and data transfer modes defined in the IEEE 960 - 1986 standard is presented. The FAstbus Slave Integrated Circuit (FASIC) is an interface between the asynchronous Fastbus and a clock synchronous processor/memory bus. It can work stand-alone or together with a 32 bit microprocessor. The FASIC is a programmable device enabling its direct use in many different applications. A set of programmable address mapping windows can map Fastbus addresses to convenient memory addresses and at the same time act as address decoding logic. Data rates of 100 MBytes/sec to Fastbus can be obtained using an internal FIFO in the FASIC to buffer data between the two buses during block transfers. Message passing from Fastbus to a microprocessor on the slave module is supported. A compact (70 mm x 170 mm) Fastbus slave piggy back sub-card interface including level conversion between ECL and TTL signal levels has been implemented using surface mount components and the 208 pin FASIC chip

  14. Accuracy assessment of high resolution satellite imagery orientation by leave-one-out method

    Science.gov (United States)

    Brovelli, Maria Antonia; Crespi, Mattia; Fratarcangeli, Francesca; Giannone, Francesca; Realini, Eugenio

    Interest in high-resolution satellite imagery (HRSI) is spreading in several application fields, at both scientific and commercial levels. Fundamental and critical goals for the geometric use of this kind of imagery are their orientation and orthorectification, processes able to georeference the imagery and correct the geometric deformations they undergo during acquisition. In order to exploit the actual potentialities of orthorectified imagery in Geomatics applications, the definition of a methodology to assess the spatial accuracy achievable from oriented imagery is a crucial topic. In this paper we want to propose a new method for accuracy assessment based on the Leave-One-Out Cross-Validation (LOOCV), a model validation method already applied in different fields such as machine learning, bioinformatics and generally in any other field requiring an evaluation of the performance of a learning algorithm (e.g. in geostatistics), but never applied to HRSI orientation accuracy assessment. The proposed method exhibits interesting features which are able to overcome the most remarkable drawbacks involved by the commonly used method (Hold-Out Validation — HOV), based on the partitioning of the known ground points in two sets: the first is used in the orientation-orthorectification model (GCPs — Ground Control Points) and the second is used to validate the model itself (CPs — Check Points). In fact the HOV is generally not reliable and it is not applicable when a low number of ground points is available. To test the proposed method we implemented a new routine that performs the LOOCV in the software SISAR, developed by the Geodesy and Geomatics Team at the Sapienza University of Rome to perform the rigorous orientation of HRSI; this routine was tested on some EROS-A and QuickBird images. Moreover, these images were also oriented using the world recognized commercial software OrthoEngine v. 10 (included in the Geomatica suite by PCI), manually performing the LOOCV

  15. High-Accuracy Measurements of Total Column Water Vapor From the Orbiting Carbon Observatory-2

    Science.gov (United States)

    Nelson, Robert R.; Crisp, David; Ott, Lesley E.; O'Dell, Christopher W.

    2016-01-01

    Accurate knowledge of the distribution of water vapor in Earth's atmosphere is of critical importance to both weather and climate studies. Here we report on measurements of total column water vapor (TCWV) from hyperspectral observations of near-infrared reflected sunlight over land and ocean surfaces from the Orbiting Carbon Observatory-2 (OCO-2). These measurements are an ancillary product of the retrieval algorithm used to measure atmospheric carbon dioxide concentrations, with information coming from three highly resolved spectral bands. Comparisons to high-accuracy validation data, including ground-based GPS and microwave radiometer data, demonstrate that OCO-2 TCWV measurements have maximum root-mean-square deviations of 0.9-1.3mm. Our results indicate that OCO-2 is the first space-based sensor to accurately and precisely measure the two most important greenhouse gases, water vapor and carbon dioxide, at high spatial resolution [1.3 x 2.3 km(exp. 2)] and that OCO-2 TCWV measurements may be useful in improving numerical weather predictions and reanalysis products.

  16. A new device for liver cancer biomarker detection with high accuracy

    Directory of Open Access Journals (Sweden)

    Shuaipeng Wang

    2015-06-01

    Full Text Available A novel cantilever array-based bio-sensor was batch-fabricated with IC compatible MEMS technology for precise liver cancer bio-marker detection. A micro-cavity was designed in the free end of the cantilever for local antibody-immobilization, thus adsorption of the cancer biomarker is localized in the micro-cavity, and the adsorption-induced k variation can be dramatically reduced with comparison to that caused by adsorption of the whole lever. The cantilever is pizeoelectrically driven into vibration which is pizeoresistively sensed by Wheatstone bridge. These structural features offer several advantages: high sensitivity, high throughput, high mass detection accuracy, and small volume. In addition, an analytical model has been established to eliminate the effect of adsorption-induced lever stiffness change and has been applied to precise mass detection of cancer biomarker AFP, the detected AFP antigen mass (7.6 pg/ml is quite close to the calculated one (5.5 pg/ml, two orders of magnitude better than the value by the fully antibody-immobilized cantilever sensor. These approaches will promote real application of the cantilever sensors in early diagnosis of cancer.

  17. Design and Performance Evaluation of Real-time Endovascular Interventional Surgical Robotic System with High Accuracy.

    Science.gov (United States)

    Wang, Kundong; Chen, Bing; Lu, Qingsheng; Li, Hongbing; Liu, Manhua; Shen, Yu; Xu, Zhuoyan

    2018-05-15

    Endovascular interventional surgery (EIS) is performed under a high radiation environment at the sacrifice of surgeons' health. This paper introduces a novel endovascular interventional surgical robot that aims to reduce radiation to surgeons and physical stress imposed by lead aprons during fluoroscopic X-ray guided catheter intervention. The unique mechanical structure allowed the surgeon to manipulate the axial and radial motion of the catheter and guide wire. Four catheter manipulators (to manipulate the catheter and guide wire), and a control console which consists of four joysticks, several buttons and two twist switches (to control the catheter manipulators) were presented. The entire robotic system was established on a master-slave control structure through CAN (Controller Area Network) bus communication, meanwhile, the slave side of this robotic system showed highly accurate control over velocity and displacement with PID controlling method. The robotic system was tested and passed in vitro and animal experiments. Through functionality evaluation, the manipulators were able to complete interventional surgical motion both independently and cooperatively. The robotic surgery was performed successfully in an adult female pig and demonstrated the feasibility of superior mesenteric and common iliac artery stent implantation. The entire robotic system met the clinical requirements of EIS. The results show that the system has the ability to imitate the movements of surgeons and to accomplish the axial and radial motions with consistency and high-accuracy. Copyright © 2018 John Wiley & Sons, Ltd.

  18. A Robust High-Accuracy Ultrasound Indoor Positioning System Based on a Wireless Sensor Network.

    Science.gov (United States)

    Qi, Jun; Liu, Guo-Ping

    2017-11-06

    This paper describes the development and implementation of a robust high-accuracy ultrasonic indoor positioning system (UIPS). The UIPS consists of several wireless ultrasonic beacons in the indoor environment. Each of them has a fixed and known position coordinate and can collect all the transmissions from the target node or emit ultrasonic signals. Every wireless sensor network (WSN) node has two communication modules: one is WiFi, that transmits the data to the server, and the other is the radio frequency (RF) module, which is only used for time synchronization between different nodes, with accuracy up to 1 μ s. The distance between the beacon and the target node is calculated by measuring the time-of-flight (TOF) for the ultrasonic signal, and then the position of the target is computed by some distances and the coordinate of the beacons. TOF estimation is the most important technique in the UIPS. A new time domain method to extract the envelope of the ultrasonic signals is presented in order to estimate the TOF. This method, with the envelope detection filter, estimates the value with the sampled values on both sides based on the least squares method (LSM). The simulation results show that the method can achieve envelope detection with a good filtering effect by means of the LSM. The highest precision and variance can reach 0.61 mm and 0.23 mm, respectively, in pseudo-range measurements with UIPS. A maximum location error of 10.2 mm is achieved in the positioning experiments for a moving robot, when UIPS works on the line-of-sight (LOS) signal.

  19. High-accuracy optical extensometer based on coordinate transform in two-dimensional digital image correlation

    Science.gov (United States)

    Lv, Zeqian; Xu, Xiaohai; Yan, Tianhao; Cai, Yulong; Su, Yong; Zhang, Qingchuan

    2018-01-01

    In the measurement of plate specimens, traditional two-dimensional (2D) digital image correlation (DIC) is challenged by two aspects: (1) the slant optical axis (misalignment of the optical camera axis and the object surface) and (2) out-of-plane motions (including translations and rotations) of the specimens. There are measurement errors in the results measured by 2D DIC, especially when the out-of-plane motions are big enough. To solve this problem, a novel compensation method has been proposed to correct the unsatisfactory results. The proposed compensation method consists of three main parts: 1) a pre-calibration step is used to determine the intrinsic parameters and lens distortions; 2) a compensation panel (a rigid panel with several markers located at known positions) is mounted to the specimen to track the specimen's motion so that the relative coordinate transformation between the compensation panel and the 2D DIC setup can be calculated using the coordinate transform algorithm; 3) three-dimensional world coordinates of measuring points on the specimen can be reconstructed via the coordinate transform algorithm and used to calculate deformations. Simulations have been carried out to validate the proposed compensation method. Results come out that when the extensometer length is 400 pixels, the strain accuracy reaches 10 με no matter out-of-plane translations (less than 1/200 of the object distance) nor out-of-plane rotations (rotation angle less than 5°) occur. The proposed compensation method leads to good results even when the out-of-plane translation reaches several percents of the object distance or the out-of-plane rotation angle reaches tens of degrees. The proposed compensation method has been applied in tensile experiments to obtain high-accuracy results as well.

  20. A Robust High-Accuracy Ultrasound Indoor Positioning System Based on a Wireless Sensor Network

    Directory of Open Access Journals (Sweden)

    Jun Qi

    2017-11-01

    Full Text Available This paper describes the development and implementation of a robust high-accuracy ultrasonic indoor positioning system (UIPS. The UIPS consists of several wireless ultrasonic beacons in the indoor environment. Each of them has a fixed and known position coordinate and can collect all the transmissions from the target node or emit ultrasonic signals. Every wireless sensor network (WSN node has two communication modules: one is WiFi, that transmits the data to the server, and the other is the radio frequency (RF module, which is only used for time synchronization between different nodes, with accuracy up to 1 μs. The distance between the beacon and the target node is calculated by measuring the time-of-flight (TOF for the ultrasonic signal, and then the position of the target is computed by some distances and the coordinate of the beacons. TOF estimation is the most important technique in the UIPS. A new time domain method to extract the envelope of the ultrasonic signals is presented in order to estimate the TOF. This method, with the envelope detection filter, estimates the value with the sampled values on both sides based on the least squares method (LSM. The simulation results show that the method can achieve envelope detection with a good filtering effect by means of the LSM. The highest precision and variance can reach 0.61 mm and 0.23 mm, respectively, in pseudo-range measurements with UIPS. A maximum location error of 10.2 mm is achieved in the positioning experiments for a moving robot, when UIPS works on the line-of-sight (LOS signal.

  1. High accuracy electromagnetic field solvers for cylindrical waveguides and axisymmetric structures using the finite element method

    International Nuclear Information System (INIS)

    Nelson, E.M.

    1993-12-01

    Some two-dimensional finite element electromagnetic field solvers are described and tested. For TE and TM modes in homogeneous cylindrical waveguides and monopole modes in homogeneous axisymmetric structures, the solvers find approximate solutions to a weak formulation of the wave equation. Second-order isoparametric lagrangian triangular elements represent the field. For multipole modes in axisymmetric structures, the solver finds approximate solutions to a weak form of the curl-curl formulation of Maxwell's equations. Second-order triangular edge elements represent the radial (ρ) and axial (z) components of the field, while a second-order lagrangian basis represents the azimuthal (φ) component of the field weighted by the radius ρ. A reduced set of basis functions is employed for elements touching the axis. With this basis the spurious modes of the curl-curl formulation have zero frequency, so spurious modes are easily distinguished from non-static physical modes. Tests on an annular ring, a pillbox and a sphere indicate the solutions converge rapidly as the mesh is refined. Computed eigenvalues with relative errors of less than a few parts per million are obtained. Boundary conditions for symmetric, periodic and symmetric-periodic structures are discussed and included in the field solver. Boundary conditions for structures with inversion symmetry are also discussed. Special corner elements are described and employed to improve the accuracy of cylindrical waveguide and monopole modes with singular fields at sharp corners. The field solver is applied to three problems: (1) cross-field amplifier slow-wave circuits, (2) a detuned disk-loaded waveguide linear accelerator structure and (3) a 90 degrees overmoded waveguide bend. The detuned accelerator structure is a critical application of this high accuracy field solver. To maintain low long-range wakefields, tight design and manufacturing tolerances are required

  2. Model Accuracy Comparison for High Resolution Insar Coherence Statistics Over Urban Areas

    Science.gov (United States)

    Zhang, Yue; Fu, Kun; Sun, Xian; Xu, Guangluan; Wang, Hongqi

    2016-06-01

    The interferometric coherence map derived from the cross-correlation of two complex registered synthetic aperture radar (SAR) images is the reflection of imaged targets. In many applications, it can act as an independent information source, or give additional information complementary to the intensity image. Specially, the statistical properties of the coherence are of great importance in land cover classification, segmentation and change detection. However, compared to the amount of work on the statistical characters of SAR intensity, there are quite fewer researches on interferometric SAR (InSAR) coherence statistics. And to our knowledge, all of the existing work that focuses on InSAR coherence statistics, models the coherence with Gaussian distribution with no discrimination on data resolutions or scene types. But the properties of coherence may be different for different data resolutions and scene types. In this paper, we investigate on the coherence statistics for high resolution data over urban areas, by making a comparison of the accuracy of several typical statistical models. Four typical land classes including buildings, trees, shadow and roads are selected as the representatives of urban areas. Firstly, several regions are selected from the coherence map manually and labelled with their corresponding classes respectively. Then we try to model the statistics of the pixel coherence for each type of region, with different models including Gaussian, Rayleigh, Weibull, Beta and Nakagami. Finally, we evaluate the model accuracy for each type of region. The experiments on TanDEM-X data show that the Beta model has a better performance than other distributions.

  3. MODEL ACCURACY COMPARISON FOR HIGH RESOLUTION INSAR COHERENCE STATISTICS OVER URBAN AREAS

    Directory of Open Access Journals (Sweden)

    Y. Zhang

    2016-06-01

    Full Text Available The interferometric coherence map derived from the cross-correlation of two complex registered synthetic aperture radar (SAR images is the reflection of imaged targets. In many applications, it can act as an independent information source, or give additional information complementary to the intensity image. Specially, the statistical properties of the coherence are of great importance in land cover classification, segmentation and change detection. However, compared to the amount of work on the statistical characters of SAR intensity, there are quite fewer researches on interferometric SAR (InSAR coherence statistics. And to our knowledge, all of the existing work that focuses on InSAR coherence statistics, models the coherence with Gaussian distribution with no discrimination on data resolutions or scene types. But the properties of coherence may be different for different data resolutions and scene types. In this paper, we investigate on the coherence statistics for high resolution data over urban areas, by making a comparison of the accuracy of several typical statistical models. Four typical land classes including buildings, trees, shadow and roads are selected as the representatives of urban areas. Firstly, several regions are selected from the coherence map manually and labelled with their corresponding classes respectively. Then we try to model the statistics of the pixel coherence for each type of region, with different models including Gaussian, Rayleigh, Weibull, Beta and Nakagami. Finally, we evaluate the model accuracy for each type of region. The experiments on TanDEM-X data show that the Beta model has a better performance than other distributions.

  4. The One to Multiple Automatic High Accuracy Registration of Terrestrial LIDAR and Optical Images

    Science.gov (United States)

    Wang, Y.; Hu, C.; Xia, G.; Xue, H.

    2018-04-01

    The registration of ground laser point cloud and close-range image is the key content of high-precision 3D reconstruction of cultural relic object. In view of the requirement of high texture resolution in the field of cultural relic at present, The registration of point cloud and image data in object reconstruction will result in the problem of point cloud to multiple images. In the current commercial software, the two pairs of registration of the two kinds of data are realized by manually dividing point cloud data, manual matching point cloud and image data, manually selecting a two - dimensional point of the same name of the image and the point cloud, and the process not only greatly reduces the working efficiency, but also affects the precision of the registration of the two, and causes the problem of the color point cloud texture joint. In order to solve the above problems, this paper takes the whole object image as the intermediate data, and uses the matching technology to realize the automatic one-to-one correspondence between the point cloud and multiple images. The matching of point cloud center projection reflection intensity image and optical image is applied to realize the automatic matching of the same name feature points, and the Rodrigo matrix spatial similarity transformation model and weight selection iteration are used to realize the automatic registration of the two kinds of data with high accuracy. This method is expected to serve for the high precision and high efficiency automatic 3D reconstruction of cultural relic objects, which has certain scientific research value and practical significance.

  5. High-resolution CT of nontuberculous mycobacterium infection in adult CF patients: diagnostic accuracy

    International Nuclear Information System (INIS)

    McEvoy, Sinead; Lavelle, Lisa; Kilcoyne, Aoife; McCarthy, Colin; Dodd, Jonathan D.; DeJong, Pim A.; Loeve, Martine; Tiddens, Harm A.W.M.; McKone, Edward; Gallagher, Charles G.

    2012-01-01

    To determine the diagnostic accuracy of high-resolution computed tomography (HRCT) for the detection of nontuberculous mycobacterium infection (NTM) in adult cystic fibrosis (CF) patients. Twenty-seven CF patients with sputum-culture-proven NTM (NTM+) underwent HRCT. An age, gender and spirometrically matched group of 27 CF patients without NTM (NTM-) was included as controls. Images were randomly and blindly analysed by two readers in consensus and scored using a modified Bhalla scoring system. Significant differences were seen between NTM (+) and NTM (-) patients in the severity of the bronchiectasis subscore [45 % (1.8/4) vs. 35 % (1.4/4), P = 0.029], collapse/consolidation subscore [33 % (1.3/3) vs. 15 % (0.6/3)], tree-in-bud/centrilobular nodules subscore [43 % (1.7/3) vs. 25 % (1.0/3), P = 0.002] and the total CT score [56 % (18.4/33) vs. 46 % (15.2/33), P = 0.002]. Binary logistic regression revealed BMI, peribronchial thickening, collapse/consolidation and tree-in-bud/centrilobular nodules to be predictors of NTM status (R 2 = 0.43). Receiver-operator curve analysis of the regression model showed an area under the curve of 0.89, P < 0.0001. In adults with CF, seven or more bronchopulmonary segments showing tree-in-bud/centrilobular nodules on HRCT is highly suggestive of NTM colonisation. (orig.)

  6. High-resolution CT of nontuberculous mycobacterium infection in adult CF patients: diagnostic accuracy

    Energy Technology Data Exchange (ETDEWEB)

    McEvoy, Sinead; Lavelle, Lisa; Kilcoyne, Aoife; McCarthy, Colin; Dodd, Jonathan D. [St. Vincent' s University Hospital, Department of Radiology, Dublin (Ireland); DeJong, Pim A. [University Medical Center Utrecht, Department of Radiology, Utrecht (Netherlands); Loeve, Martine; Tiddens, Harm A.W.M. [Erasmus MC-Sophia Children' s Hospital, Department of Radiology, Department of Pediatric Pulmonology and Allergology, Rotterdam (Netherlands); McKone, Edward; Gallagher, Charles G. [St. Vincent' s University Hospital, Department of Respiratory Medicine and National Referral Centre for Adult Cystic Fibrosis, Dublin (Ireland)

    2012-12-15

    To determine the diagnostic accuracy of high-resolution computed tomography (HRCT) for the detection of nontuberculous mycobacterium infection (NTM) in adult cystic fibrosis (CF) patients. Twenty-seven CF patients with sputum-culture-proven NTM (NTM+) underwent HRCT. An age, gender and spirometrically matched group of 27 CF patients without NTM (NTM-) was included as controls. Images were randomly and blindly analysed by two readers in consensus and scored using a modified Bhalla scoring system. Significant differences were seen between NTM (+) and NTM (-) patients in the severity of the bronchiectasis subscore [45 % (1.8/4) vs. 35 % (1.4/4), P = 0.029], collapse/consolidation subscore [33 % (1.3/3) vs. 15 % (0.6/3)], tree-in-bud/centrilobular nodules subscore [43 % (1.7/3) vs. 25 % (1.0/3), P = 0.002] and the total CT score [56 % (18.4/33) vs. 46 % (15.2/33), P = 0.002]. Binary logistic regression revealed BMI, peribronchial thickening, collapse/consolidation and tree-in-bud/centrilobular nodules to be predictors of NTM status (R{sup 2} = 0.43). Receiver-operator curve analysis of the regression model showed an area under the curve of 0.89, P < 0.0001. In adults with CF, seven or more bronchopulmonary segments showing tree-in-bud/centrilobular nodules on HRCT is highly suggestive of NTM colonisation. (orig.)

  7. Rigorous Training of Dogs Leads to High Accuracy in Human Scent Matching-To-Sample Performance.

    Directory of Open Access Journals (Sweden)

    Sophie Marchal

    Full Text Available Human scent identification is based on a matching-to-sample task in which trained dogs are required to compare a scent sample collected from an object found at a crime scene to that of a suspect. Based on dogs' greater olfactory ability to detect and process odours, this method has been used in forensic investigations to identify the odour of a suspect at a crime scene. The excellent reliability and reproducibility of the method largely depend on rigor in dog training. The present study describes the various steps of training that lead to high sensitivity scores, with dogs matching samples with 90% efficiency when the complexity of the scents presented during the task in the sample is similar to that presented in the in lineups, and specificity reaching a ceiling, with no false alarms in human scent matching-to-sample tasks. This high level of accuracy ensures reliable results in judicial human scent identification tests. Also, our data should convince law enforcement authorities to use these results as official forensic evidence when dogs are trained appropriately.

  8. Spline-based high-accuracy piecewise-polynomial phase-to-sinusoid amplitude converters.

    Science.gov (United States)

    Petrinović, Davor; Brezović, Marko

    2011-04-01

    We propose a method for direct digital frequency synthesis (DDS) using a cubic spline piecewise-polynomial model for a phase-to-sinusoid amplitude converter (PSAC). This method offers maximum smoothness of the output signal. Closed-form expressions for the cubic polynomial coefficients are derived in the spectral domain and the performance analysis of the model is given in the time and frequency domains. We derive the closed-form performance bounds of such DDS using conventional metrics: rms and maximum absolute errors (MAE) and maximum spurious free dynamic range (SFDR) measured in the discrete time domain. The main advantages of the proposed PSAC are its simplicity, analytical tractability, and inherent numerical stability for high table resolutions. Detailed guidelines for a fixed-point implementation are given, based on the algebraic analysis of all quantization effects. The results are verified on 81 PSAC configurations with the output resolutions from 5 to 41 bits by using a bit-exact simulation. The VHDL implementation of a high-accuracy DDS based on the proposed PSAC with 28-bit input phase word and 32-bit output value achieves SFDR of its digital output signal between 180 and 207 dB, with a signal-to-noise ratio of 192 dB. Its implementation requires only one 18 kB block RAM and three 18-bit embedded multipliers in a typical field-programmable gate array (FPGA) device. © 2011 IEEE

  9. Fabrication of Phosphate Cement with High Integrity

    International Nuclear Information System (INIS)

    Yang, Jae Hwan; Lee, Chang Hwa; Heo, Cheol Min; Jeon, Min Ku; Kang, Kweon Ho

    2011-01-01

    As the development of industrial society has accelerated, hazardous wastes are generated as well. According to the 1986 statistics of U.S.A, each person made 40 tons of waste in America that year. Treatment of radioactive waste is one of the most important and serious problems related to waste treatments, because its radioactivity and decaying heat have harmful effects to human and environment for a long time. Nuclear developed countries have used conventional method of treatment such as vitrification or cementation in order to stabilize and solidify radioactive waste. Although the former guarantees the formation of high leaching resistant and durable waste form, it requires several hundred (or even more than one thousand) temperature to melt glass frit. This process generates secondary waste volatilized, as well as being non-economical. Cement technology played a role of immobilizing low and middle class wastes. It has advantages of low temperature setting, low cost, easy process, etc. The alkalinity of ordinary cement, however, constrains the utility of cement to the solidification of alkaline waste. In addition, leachability and mechanical strength of cements are not quite appropriate for the stabilization of high level waste. In this regard, chemically bonded phosphate cement(CBPC), which sets by an acid-base reaction, is a potentially expectable material for immobilization of radioactive waste. CBPC not only sets at room temperature, but also encapsulates various isotopes chemically. The performance of CBPC can be enhanced by the addition of fly ash, sand, wollastonite, etc. This study aims at fabricating the CBPC containing fly ash with high integrity. Morphology, microstructure, and compressive strength are evaluated using SEM, and digital compressing machine

  10. Design and simulation of high accuracy power supplies for injector synchrotron dipole magnets

    International Nuclear Information System (INIS)

    Fathizadeh, M.

    1991-01-01

    The ring magnet of the injector synchrotron consists of 68 dipole magnets. These magnets are connected in series and are energized from two feed points 180 degrees apart by two identical 12-phase power supplies. The current in the magnet will be raised linearly at about 1 kA level, and after a small transition period (1 ms to 10 ms typical) the current will be reduced to below the injection level of 60 A. The repetition time for the current waveform is 500 ms. A relatively fast voltage loop along with a high gain current loop are utilized to control the current in the magnet with the required accuracy. Only one regulator circuit is used to control the firing pulses of the two sets of identical 12-phase power supplies. Pspice software was used to design and simulate the power supply performance under ramping and investigate the effect of current changes on the utility voltage and input power factor. A current ripple of ±2x10 -4 and tracking error of ±5x10 -4 was needed. 3 refs., 5 figs

  11. High accuracy line positions of the ν 1 fundamental band of 14 N 2 16 O

    KAUST Repository

    Alsaif, Bidoor

    2018-03-08

    The ν1 fundamental band of N2O is examined by a novel spectrometer that relies on the frequency locking of an external-cavity quantum cascade laser around 7.8 μm to a near-infrared Tm:based frequency comb at 1.9 μm. Due to the large tunability, nearly 70 lines in the 1240 – 1310 cm−1 range of the ν1 band of N2O, from P(40) to R(31), are for the first time measured with an absolute frequency calibration and an uncertainty from 62 to 180 kHz, depending on the line. Accurate values of the spectroscopic constants of the upper state are derived from a fit of the line centers (rms ≈ 4.8 × 10−6 cm−1 or 144 kHz). The ν1 transitions presently measured in a Doppler regime validate high accuracy predictions based on sub-Doppler measurements of the ν3 and ν3-ν1 transitions.

  12. Coronary CT angiography using prospective ECG triggering. High diagnostic accuracy with low radiation dose

    International Nuclear Information System (INIS)

    Arnoldi, E.; Ramos-Duran, L.; Abro, J.A.; Costello, P.; Zwerner, P.L.; Schoepf, U.J.; Nikolaou, K.; Reiser, M.F.

    2010-01-01

    The purpose of this study was to evaluate the diagnostic performance of coronary CT angiography (coronary CTA) using prospective ECG triggering (PT) for the detection of significant coronary artery stenosis compared to invasive coronary angiography (ICA). A total of 20 patients underwent coronary CTA with PT using a 128-slice CT scanner (Definition trademark AS+, Siemens) and ICA. All coronary CTA studies were evaluated for significant coronary artery stenoses (≥50% luminal narrowing) by 2 observers in consensus using the AHA-15-segment model. Findings in CTA were compared to those in ICA. Coronary CTA using PT had 88% sensitivity in comparison to 100% with ICA, 95% to 88% specificity, 80% to 92% positive predictive value and 97% to 100% negative predictive value for diagnosing significant coronary artery stenosis on per segment per patient analysis, respectively. Mean effective radiation dose-equivalent of CTA was 2.6±1 mSv. Coronary CTA using PT enables non-invasive diagnosis of significant coronary artery stenosis with high diagnostic accuracy in comparison to ICA and is associated with comparably low radiation exposure. (orig.) [de

  13. High accuracy line positions of the ν1 fundamental band of 14N216O

    Science.gov (United States)

    AlSaif, Bidoor; Lamperti, Marco; Gatti, Davide; Laporta, Paolo; Fermann, Martin; Farooq, Aamir; Lyulin, Oleg; Campargue, Alain; Marangoni, Marco

    2018-05-01

    The ν1 fundamental band of N2O is examined by a novel spectrometer that relies on the frequency locking of an external-cavity quantum cascade laser around 7.8 μm to a near-infrared Tm:based frequency comb at 1.9 μm. Due to the large tunability, nearly 70 lines in the 1240-1310 cm-1 range of the ν1 band of N2O, from P(40) to R(31), are for the first time measured with an absolute frequency calibration and an uncertainty from 62 to 180 kHz, depending on the line. Accurate values of the spectroscopic constants of the upper state are derived from a fit of the line centers (rms ≈ 4.8 × 10-6 cm-1 or 144 kHz). The ν1 transitions presently measured in a Doppler regime validate high accuracy predictions based on sub-Doppler measurements of the ν3 and ν3-ν1 transitions.

  14. On the impact of improved dosimetric accuracy on head and neck high dose rate brachytherapy.

    Science.gov (United States)

    Peppa, Vasiliki; Pappas, Eleftherios; Major, Tibor; Takácsi-Nagy, Zoltán; Pantelis, Evaggelos; Papagiannis, Panagiotis

    2016-07-01

    To study the effect of finite patient dimensions and tissue heterogeneities in head and neck high dose rate brachytherapy. The current practice of TG-43 dosimetry was compared to patient specific dosimetry obtained using Monte Carlo simulation for a sample of 22 patient plans. The dose distributions were compared in terms of percentage dose differences as well as differences in dose volume histogram and radiobiological indices for the target and organs at risk (mandible, parotids, skin, and spinal cord). Noticeable percentage differences exist between TG-43 and patient specific dosimetry, mainly at low dose points. Expressed as fractions of the planning aim dose, percentage differences are within 2% with a general TG-43 overestimation except for the spine. These differences are consistent resulting in statistically significant differences of dose volume histogram and radiobiology indices. Absolute differences of these indices are however small to warrant clinical importance in terms of tumor control or complication probabilities. The introduction of dosimetry methods characterized by improved accuracy is a valuable advancement. It does not appear however to influence dose prescription or call for amendment of clinical recommendations for the mobile tongue, base of tongue, and floor of mouth patient cohort of this study. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  15. Design and simulation of high accuracy power supplies for injector synchrotron dipole magnets

    International Nuclear Information System (INIS)

    Fathizadeh, M.

    1991-01-01

    The ring magnet of the injector synchrotron consists of 68 dipole magnets. These magnets are connected in series and are energized from two feed points 180 degree apart by two identical 12-phase power supplies. The current in the magnet will be raised linearly to about 1 kA level, and after a small transition period (1 ms to 10 ms typical) the current will be reduced to below the injection level of 60 A. The repetition time for the current waveform is 500 ms. A relatively fast voltage loop along with a high gain current loop are utilized to control the current in the magnet with the required accuracy. Only one regulator circuit is used to control the firing pulses of the two sets of identical 12-phase power supplies. Pspice software was used to design and simulate the power supply performance under ramping and investigate the effect of current changes on the utility voltage and input power factor. A current ripple of ± 2 x 10 -4 and tracking error of ± 5 x 10 -4 was needed

  16. Quantitative accuracy of serotonergic neurotransmission imaging with high-resolution 123I SPECT

    International Nuclear Information System (INIS)

    Kuikka, J.T.

    2004-01-01

    Aim: Serotonin transporter (SERT) imaging can be used to study the role of regional abnormalities of neurotransmitter release in various mental disorders and to study the mechanism of action of therapeutic drugs or drugs' abuse. We examine the quantitative accuracy and reproducibility that can be achieved with high-resolution SPECT of serotonergic neurotransmission. Method: Binding potential (BP) of 123 I labeled tracer specific for midbrain SERT was assessed in 20 healthy persons. The effects of scatter, attenuation, partial volume, misregistration and statistical noise were estimated using phantom and human studies. Results: Without any correction, BP was underestimated by 73%. The partial volume error was the major component in this underestimation whereas the most critical error for the reproducibility was misplacement of region of interest (ROI). Conclusion: The proper ROI registration, the use of the multiple head gamma camera with transmission based scatter correction introduce more relevant results. However, due to the small dimensions of the midbrain SERT structures and poor spatial resolution of SPECT, the improvement without the partial volume correction is not great enough to restore the estimate of BP to that of the true one. (orig.) [de

  17. High Accuracy Ground-based near-Earth-asteroid Astrometry using Synthetic Tracking

    Science.gov (United States)

    Zhai, Chengxing; Shao, Michael; Saini, Navtej; Sandhu, Jagmit; Werne, Thomas; Choi, Philip; Ely, Todd A.; Jacobs, Chirstopher S.; Lazio, Joseph; Martin-Mur, Tomas J.; Owen, William M.; Preston, Robert; Turyshev, Slava; Michell, Adam; Nazli, Kutay; Cui, Isaac; Monchama, Rachel

    2018-01-01

    Accurate astrometry is crucial for determining the orbits of near-Earth-asteroids (NEAs). Further, the future of deep space high data rate communications is likely to be optical communications, such as the Deep Space Optical Communications package that is part of the baseline payload for the planned Psyche Discovery mission to the Psyche asteroid. We have recently upgraded our instrument on the Pomona College 1 m telescope, at JPL's Table Mountain Facility, for conducting synthetic tracking by taking many short exposure images. These images can be then combined in post-processing to track both asteroid and reference stars to yield accurate astrometry. Utilizing the precision of the current and future Gaia data releases, the JPL-Pomona College effort is now demonstrating precision astrometry on NEAs, which is likely to be of considerable value for cataloging NEAs. Further, treating NEAs as proxies of future spacecraft that carry optical communication lasers, our results serve as a measure of the astrometric accuracy that could be achieved for future plane-of-sky optical navigation.

  18. High-Resolution Integrated Optical System

    Science.gov (United States)

    Prakapenka, V. B.; Goncharov, A. F.; Holtgrewe, N.; Greenberg, E.

    2017-12-01

    Raman and optical spectroscopy in-situ at extreme high pressure and temperature conditions relevant to the planets' deep interior is a versatile tool for characterization of wide range of properties of minerals essential for understanding the structure, composition, and evolution of terrestrial and giant planets. Optical methods, greatly complementing X-ray diffraction and spectroscopy techniques, become crucial when dealing with light elements. Study of vibrational and optical properties of minerals and volatiles, was a topic of many research efforts in past decades. A great deal of information on the materials properties under extreme pressure and temperature has been acquired including that related to structural phase changes, electronic transitions, and chemical transformations. These provide an important insight into physical and chemical states of planetary interiors (e.g. nature of deep reservoirs) and their dynamics including heat and mass transport (e.g. deep carbon cycle). Optical and vibrational spectroscopy can be also very instrumental for elucidating the nature of the materials molten states such as those related to the Earth's volatiles (CO2, CH4, H2O), aqueous fluids and silicate melts, planetary ices (H2O, CH4, NH3), noble gases, and H2. The optical spectroscopy study performed concomitantly with X-ray diffraction and spectroscopy measurements at the GSECARS beamlines on the same sample and at the same P-T conditions would greatly enhance the quality of this research and, moreover, will provide unique new information on chemical state of matter. The advanced high-resolution user-friendly integrated optical system is currently under construction and expected to be completed by 2018. In our conceptual design we have implemented Raman spectroscopy with five excitation wavelengths (266, 473, 532, 660, 946 nm), confocal imaging, double sided IR laser heating combined with high temperature Raman (including coherent anti-Stokes Raman scattering) and

  19. The accuracy of the Gaussian-and-finite-element-Coulomb (GFC) method for the calculation of Coulomb integrals.

    Science.gov (United States)

    Przybytek, Michal; Helgaker, Trygve

    2013-08-07

    We analyze the accuracy of the Coulomb energy calculated using the Gaussian-and-finite-element-Coulomb (GFC) method. In this approach, the electrostatic potential associated with the molecular electronic density is obtained by solving the Poisson equation and then used to calculate matrix elements of the Coulomb operator. The molecular electrostatic potential is expanded in a mixed Gaussian-finite-element (GF) basis set consisting of Gaussian functions of s symmetry centered on the nuclei (with exponents obtained from a full optimization of the atomic potentials generated by the atomic densities from symmetry-averaged restricted open-shell Hartree-Fock theory) and shape functions defined on uniform finite elements. The quality of the GF basis is controlled by means of a small set of parameters; for a given width of the finite elements d, the highest accuracy is achieved at smallest computational cost when tricubic (n = 3) elements are used in combination with two (γ(H) = 2) and eight (γ(1st) = 8) Gaussians on hydrogen and first-row atoms, respectively, with exponents greater than a given threshold (αmin (G)=0.5). The error in the calculated Coulomb energy divided by the number of atoms in the system depends on the system type but is independent of the system size or the orbital basis set, vanishing approximately like d(4) with decreasing d. If the boundary conditions for the Poisson equation are calculated in an approximate way, the GFC method may lose its variational character when the finite elements are too small; with larger elements, it is less sensitive to inaccuracies in the boundary values. As it is possible to obtain accurate boundary conditions in linear time, the overall scaling of the GFC method for large systems is governed by another computational step-namely, the generation of the three-center overlap integrals with three Gaussian orbitals. The most unfavorable (nearly quadratic) scaling is observed for compact, truly three-dimensional systems

  20. Integrating advanced facades into high performance buildings

    International Nuclear Information System (INIS)

    Selkowitz, Stephen E.

    2001-01-01

    Glass is a remarkable material but its functionality is significantly enhanced when it is processed or altered to provide added intrinsic capabilities. The overall performance of glass elements in a building can be further enhanced when they are designed to be part of a complete facade system. Finally the facade system delivers the greatest performance to the building owner and occupants when it becomes an essential element of a fully integrated building design. This presentation examines the growing interest in incorporating advanced glazing elements into more comprehensive facade and building systems in a manner that increases comfort, productivity and amenity for occupants, reduces operating costs for building owners, and contributes to improving the health of the planet by reducing overall energy use and negative environmental impacts. We explore the role of glazing systems in dynamic and responsive facades that provide the following functionality: Enhanced sun protection and cooling load control while improving thermal comfort and providing most of the light needed with daylighting; Enhanced air quality and reduced cooling loads using natural ventilation schemes employing the facade as an active air control element; Reduced operating costs by minimizing lighting, cooling and heating energy use by optimizing the daylighting-thermal tradeoffs; Net positive contributions to the energy balance of the building using integrated photovoltaic systems; Improved indoor environments leading to enhanced occupant health, comfort and performance. In addressing these issues facade system solutions must, of course, respect the constraints of latitude, location, solar orientation, acoustics, earthquake and fire safety, etc. Since climate and occupant needs are dynamic variables, in a high performance building the facade solution have the capacity to respond and adapt to these variable exterior conditions and to changing occupant needs. This responsive performance capability

  1. Achieving numerical accuracy and high performance using recursive tile LU factorization with partial pivoting

    KAUST Repository

    Dongarra, Jack

    2013-09-18

    The LU factorization is an important numerical algorithm for solving systems of linear equations in science and engineering and is a characteristic of many dense linear algebra computations. For example, it has become the de facto numerical algorithm implemented within the LINPACK benchmark to rank the most powerful supercomputers in the world, collected by the TOP500 website. Multicore processors continue to present challenges to the development of fast and robust numerical software due to the increasing levels of hardware parallelism and widening gap between core and memory speeds. In this context, the difficulty in developing new algorithms for the scientific community resides in the combination of two goals: achieving high performance while maintaining the accuracy of the numerical algorithm. This paper proposes a new approach for computing the LU factorization in parallel on multicore architectures, which not only improves the overall performance but also sustains the numerical quality of the standard LU factorization algorithm with partial pivoting. While the update of the trailing submatrix is computationally intensive and highly parallel, the inherently problematic portion of the LU factorization is the panel factorization due to its memory-bound characteristic as well as the atomicity of selecting the appropriate pivots. Our approach uses a parallel fine-grained recursive formulation of the panel factorization step and implements the update of the trailing submatrix with the tile algorithm. Based on conflict-free partitioning of the data and lockless synchronization mechanisms, our implementation lets the overall computation flow naturally without contention. The dynamic runtime system called QUARK is then able to schedule tasks with heterogeneous granularities and to transparently introduce algorithmic lookahead. The performance results of our implementation are competitive compared to the currently available software packages and libraries. For example

  2. Achieving numerical accuracy and high performance using recursive tile LU factorization with partial pivoting

    KAUST Repository

    Dongarra, Jack; Faverge, Mathieu; Ltaief, Hatem; Luszczek, Piotr R.

    2013-01-01

    The LU factorization is an important numerical algorithm for solving systems of linear equations in science and engineering and is a characteristic of many dense linear algebra computations. For example, it has become the de facto numerical algorithm implemented within the LINPACK benchmark to rank the most powerful supercomputers in the world, collected by the TOP500 website. Multicore processors continue to present challenges to the development of fast and robust numerical software due to the increasing levels of hardware parallelism and widening gap between core and memory speeds. In this context, the difficulty in developing new algorithms for the scientific community resides in the combination of two goals: achieving high performance while maintaining the accuracy of the numerical algorithm. This paper proposes a new approach for computing the LU factorization in parallel on multicore architectures, which not only improves the overall performance but also sustains the numerical quality of the standard LU factorization algorithm with partial pivoting. While the update of the trailing submatrix is computationally intensive and highly parallel, the inherently problematic portion of the LU factorization is the panel factorization due to its memory-bound characteristic as well as the atomicity of selecting the appropriate pivots. Our approach uses a parallel fine-grained recursive formulation of the panel factorization step and implements the update of the trailing submatrix with the tile algorithm. Based on conflict-free partitioning of the data and lockless synchronization mechanisms, our implementation lets the overall computation flow naturally without contention. The dynamic runtime system called QUARK is then able to schedule tasks with heterogeneous granularities and to transparently introduce algorithmic lookahead. The performance results of our implementation are competitive compared to the currently available software packages and libraries. For example

  3. Factors Determining the Inter-observer Variability and Diagnostic Accuracy of High-resolution Manometry for Esophageal Motility Disorders.

    Science.gov (United States)

    Kim, Ji Hyun; Kim, Sung Eun; Cho, Yu Kyung; Lim, Chul-Hyun; Park, Moo In; Hwang, Jin Won; Jang, Jae-Sik; Oh, Minkyung

    2018-01-30

    Although high-resolution manometry (HRM) has the advantage of visual intuitiveness, its diagnostic validity remains under debate. The aim of this study was to evaluate the diagnostic accuracy of HRM for esophageal motility disorders. Six staff members and 8 trainees were recruited for the study. In total, 40 patients enrolled in manometry studies at 3 institutes were selected. Captured images of 10 representative swallows and a single swallow in analyzing mode in both high-resolution pressure topography (HRPT) and conventional line tracing formats were provided with calculated metrics. Assessments of esophageal motility disorders showed fair agreement for HRPT and moderate agreement for conventional line tracing (κ = 0.40 and 0.58, respectively). With the HRPT format, the k value was higher in category A (esophagogastric junction [EGJ] relaxation abnormality) than in categories B (major body peristalsis abnormalities with intact EGJ relaxation) and C (minor body peristalsis abnormalities or normal body peristalsis with intact EGJ relaxation). The overall exact diagnostic accuracy for the HRPT format was 58.8% and rater's position was an independent factor for exact diagnostic accuracy. The diagnostic accuracy for major disorders was 63.4% with the HRPT format. The frequency of major discrepancies was higher for category B disorders than for category A disorders (38.4% vs 15.4%; P < 0.001). The interpreter's experience significantly affected the exact diagnostic accuracy of HRM for esophageal motility disorders. The diagnostic accuracy for major disorders was higher for achalasia than distal esophageal spasm and jackhammer esophagus.

  4. DIRECT GEOREFERENCING : A NEW STANDARD IN PHOTOGRAMMETRY FOR HIGH ACCURACY MAPPING

    Directory of Open Access Journals (Sweden)

    A. Rizaldy

    2012-07-01

    Full Text Available Direct georeferencing is a new method in photogrammetry, especially in the digital camera era. Theoretically, this method does not require ground control points (GCP and the Aerial Triangulation (AT, to process aerial photography into ground coordinates. Compared with the old method, this method has three main advantages: faster data processing, simple workflow and less expensive project, at the same accuracy. Direct georeferencing using two devices, GPS and IMU. GPS recording the camera coordinates (X, Y, Z, and IMU recording the camera orientation (omega, phi, kappa. Both parameters merged into Exterior Orientation (EO parameter. This parameters required for next steps in the photogrammetric projects, such as stereocompilation, DSM generation, orthorectification and mosaic. Accuracy of this method was tested on topographic map project in Medan, Indonesia. Large-format digital camera Ultracam X from Vexcel is used, while the GPS / IMU is IGI AeroControl. 19 Independent Check Point (ICP were used to determine the accuracy. Horizontal accuracy is 0.356 meters and vertical accuracy is 0.483 meters. Data with this accuracy can be used for 1:2.500 map scale project.

  5. Towards Building Reliable, High-Accuracy Solar Irradiance Database For Arid Climates

    Science.gov (United States)

    Munawwar, S.; Ghedira, H.

    2012-12-01

    Middle East's growing interest in renewable energy has led to increased activity in solar technology development with the recent commissioning of several utility-scale solar power projects and many other commercial installations across the Arabian Peninsula. The region, lying in a virtually rainless sunny belt with a typical daily average solar radiation exceeding 6 kWh/m2, is also one of the most promising candidates for solar energy deployment. However, it is not the availability of resource, but its characterization and reasonably accurate assessment that determines the application potential. Solar irradiance, magnitude and variability inclusive, is the key input in assessing the economic feasibility of a solar system. The accuracy of such data is of critical importance for realistic on-site performance estimates. This contribution aims to identify the key stages in developing a robust solar database for desert climate by focusing on the challenges that an arid environment presents to parameterization of solar irradiance attenuating factors. Adjustments are proposed based on the currently available resource assessment tools to produce high quality data for assessing bankability. Establishing and maintaining ground solar irradiance measurements is an expensive affair and fairly limited in time (recently operational) and space (fewer sites) in the Gulf region. Developers within solar technology industry, therefore, rely on solar radiation models and satellite-derived data for prompt resource assessment needs. It is imperative that such estimation tools are as accurate as possible. While purely empirical models have been widely researched and validated in the Arabian Peninsula's solar modeling history, they are known to be intrinsically site-specific. A primal step to modeling is an in-depth understanding of the region's climate, identifying the key players attenuating radiation and their appropriate characterization to determine solar irradiance. Physical approach

  6. On the accuracy and reproducibility of a novel probabilistic atlas-based generation for calculation of head attenuation maps on integrated PET/MR scanners.

    Science.gov (United States)

    Chen, Kevin T; Izquierdo-Garcia, David; Poynton, Clare B; Chonde, Daniel B; Catana, Ciprian

    2017-03-01

    To propose an MR-based method for generating continuous-valued head attenuation maps and to assess its accuracy and reproducibility. Demonstrating that novel MR-based photon attenuation correction methods are both accurate and reproducible is essential prior to using them routinely in research and clinical studies on integrated PET/MR scanners. Continuous-valued linear attenuation coefficient maps ("μ-maps") were generated by combining atlases that provided the prior probability of voxel positions belonging to a certain tissue class (air, soft tissue, or bone) and an MR intensity-based likelihood classifier to produce posterior probability maps of tissue classes. These probabilities were used as weights to generate the μ-maps. The accuracy of this probabilistic atlas-based continuous-valued μ-map ("PAC-map") generation method was assessed by calculating the voxel-wise absolute relative change (RC) between the MR-based and scaled CT-based attenuation-corrected PET images. To assess reproducibility, we performed pair-wise comparisons of the RC values obtained from the PET images reconstructed using the μ-maps generated from the data acquired at three time points. The proposed method produced continuous-valued μ-maps that qualitatively reflected the variable anatomy in patients with brain tumor and agreed well with the scaled CT-based μ-maps. The absolute RC comparing the resulting PET volumes was 1.76 ± 2.33 %, quantitatively demonstrating that the method is accurate. Additionally, we also showed that the method is highly reproducible, the mean RC value for the PET images reconstructed using the μ-maps obtained at the three visits being 0.65 ± 0.95 %. Accurate and highly reproducible continuous-valued head μ-maps can be generated from MR data using a probabilistic atlas-based approach.

  7. On the accuracy and reproducibility of a novel probabilistic atlas-based generation for calculation of head attenuation maps on integrated PET/MR scanners

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Kevin T. [Massachusetts General Hospital and Harvard Medical School, Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Charlestown, MA (United States); Massachusetts Institute of Technology, Division of Health Sciences and Technology, Cambridge, MA (United States); Izquierdo-Garcia, David; Catana, Ciprian [Massachusetts General Hospital and Harvard Medical School, Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Charlestown, MA (United States); Poynton, Clare B. [Massachusetts General Hospital and Harvard Medical School, Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Charlestown, MA (United States); Massachusetts General Hospital, Department of Psychiatry, Boston, MA (United States); University of California, San Francisco, Department of Radiology and Biomedical Imaging, San Francisco, CA (United States); Chonde, Daniel B. [Massachusetts General Hospital and Harvard Medical School, Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Charlestown, MA (United States); Harvard University, Program in Biophysics, Cambridge, MA (United States)

    2017-03-15

    To propose an MR-based method for generating continuous-valued head attenuation maps and to assess its accuracy and reproducibility. Demonstrating that novel MR-based photon attenuation correction methods are both accurate and reproducible is essential prior to using them routinely in research and clinical studies on integrated PET/MR scanners. Continuous-valued linear attenuation coefficient maps (''μ-maps'') were generated by combining atlases that provided the prior probability of voxel positions belonging to a certain tissue class (air, soft tissue, or bone) and an MR intensity-based likelihood classifier to produce posterior probability maps of tissue classes. These probabilities were used as weights to generate the μ-maps. The accuracy of this probabilistic atlas-based continuous-valued μ-map (''PAC-map'') generation method was assessed by calculating the voxel-wise absolute relative change (RC) between the MR-based and scaled CT-based attenuation-corrected PET images. To assess reproducibility, we performed pair-wise comparisons of the RC values obtained from the PET images reconstructed using the μ-maps generated from the data acquired at three time points. The proposed method produced continuous-valued μ-maps that qualitatively reflected the variable anatomy in patients with brain tumor and agreed well with the scaled CT-based μ-maps. The absolute RC comparing the resulting PET volumes was 1.76 ± 2.33 %, quantitatively demonstrating that the method is accurate. Additionally, we also showed that the method is highly reproducible, the mean RC value for the PET images reconstructed using the μ-maps obtained at the three visits being 0.65 ± 0.95 %. Accurate and highly reproducible continuous-valued head μ-maps can be generated from MR data using a probabilistic atlas-based approach. (orig.)

  8. In-depth, high-accuracy proteomics of sea urchin tooth organic matrix

    Directory of Open Access Journals (Sweden)

    Mann Matthias

    2008-12-01

    Full Text Available Abstract Background The organic matrix contained in biominerals plays an important role in regulating mineralization and in determining biomineral properties. However, most components of biomineral matrices remain unknown at present. In sea urchin tooth, which is an important model for developmental biology and biomineralization, only few matrix components have been identified. The recent publication of the Strongylocentrotus purpuratus genome sequence rendered possible not only the identification of genes potentially coding for matrix proteins, but also the direct identification of proteins contained in matrices of skeletal elements by in-depth, high-accuracy proteomic analysis. Results We identified 138 proteins in the matrix of tooth powder. Only 56 of these proteins were previously identified in the matrices of test (shell and spine. Among the novel components was an interesting group of five proteins containing alanine- and proline-rich neutral or basic motifs separated by acidic glycine-rich motifs. In addition, four of the five proteins contained either one or two predicted Kazal protease inhibitor domains. The major components of tooth matrix were however largely identical to the set of spicule matrix proteins and MSP130-related proteins identified in test (shell and spine matrix. Comparison of the matrices of crushed teeth to intact teeth revealed a marked dilution of known intracrystalline matrix proteins and a concomitant increase in some intracellular proteins. Conclusion This report presents the most comprehensive list of sea urchin tooth matrix proteins available at present. The complex mixture of proteins identified may reflect many different aspects of the mineralization process. A comparison between intact tooth matrix, presumably containing odontoblast remnants, and crushed tooth matrix served to differentiate between matrix components and possible contributions of cellular remnants. Because LC-MS/MS-based methods directly

  9. Automated, high accuracy classification of Parkinsonian disorders: a pattern recognition approach.

    Directory of Open Access Journals (Sweden)

    Andre F Marquand

    Full Text Available Progressive supranuclear palsy (PSP, multiple system atrophy (MSA and idiopathic Parkinson's disease (IPD can be clinically indistinguishable, especially in the early stages, despite distinct patterns of molecular pathology. Structural neuroimaging holds promise for providing objective biomarkers for discriminating these diseases at the single subject level but all studies to date have reported incomplete separation of disease groups. In this study, we employed multi-class pattern recognition to assess the value of anatomical patterns derived from a widely available structural neuroimaging sequence for automated classification of these disorders. To achieve this, 17 patients with PSP, 14 with IPD and 19 with MSA were scanned using structural MRI along with 19 healthy controls (HCs. An advanced probabilistic pattern recognition approach was employed to evaluate the diagnostic value of several pre-defined anatomical patterns for discriminating the disorders, including: (i a subcortical motor network; (ii each of its component regions and (iii the whole brain. All disease groups could be discriminated simultaneously with high accuracy using the subcortical motor network. The region providing the most accurate predictions overall was the midbrain/brainstem, which discriminated all disease groups from one another and from HCs. The subcortical network also produced more accurate predictions than the whole brain and all of its constituent regions. PSP was accurately predicted from the midbrain/brainstem, cerebellum and all basal ganglia compartments; MSA from the midbrain/brainstem and cerebellum and IPD from the midbrain/brainstem only. This study demonstrates that automated analysis of structural MRI can accurately predict diagnosis in individual patients with Parkinsonian disorders, and identifies distinct patterns of regional atrophy particularly useful for this process.

  10. High accuracy of arterial spin labeling perfusion imaging in differentiation of pilomyxoid from pilocytic astrocytoma

    Energy Technology Data Exchange (ETDEWEB)

    Nabavizadeh, S.A.; Assadsangabi, R.; Hajmomenian, M.; Vossough, A. [Perelman School of Medicine of the University of Pennsylvania, Department of Radiology, Children' s Hospital of Philadelphia, Philadelphia, PA (United States); Santi, M. [Perelman School of Medicine of the University of Pennsylvania, Department of Pathology, Children' s Hospital of Philadelphia, Philadelphia, PA (United States)

    2015-05-01

    Pilomyxoid astrocytoma (PMA) is a relatively new tumor entity which has been added to the 2007 WHO Classification of tumors of the central nervous system. The goal of this study is to utilize arterial spin labeling (ASL) perfusion imaging to differentiate PMA from pilocytic astrocytoma (PA). Pulsed ASL and conventional MRI sequences of patients with PMA and PA in the past 5 years were retrospectively evaluated. Patients with history of radiation or treatment with anti-angiogenic drugs were excluded. A total of 24 patients (9 PMA, 15 PA) were included. There were statistically significant differences between PMA and PA in mean tumor/gray matter (GM) cerebral blood flow (CBF) ratios (1.3 vs 0.4, p < 0.001) and maximum tumor/GM CBF ratio (2.3 vs 1, p < 0.001). Area under the receiver operating characteristic (ROC) curves for differentiation of PMA from PA was 0.91 using mean tumor CBF, 0.95 using mean tumor/GM CBF ratios, and 0.89 using maximum tumor/GM CBF. Using a threshold value of 0.91, the mean tumor/GM CBF ratio was able to diagnose PMA with 77 % sensitivity, 100 % specificity, and a threshold value of 0.7, provided 88 % sensitivity and 86 % specificity. There was no statistically significant difference between the two tumors in enhancement pattern (p = 0.33), internal architecture (p = 0.15), or apparent diffusion coefficient (ADC) values (p = 0.07). ASL imaging has high accuracy in differentiating PMA from PA. The result of this study may have important applications in prognostication and treatment planning especially in patients with less accessible tumors such as hypothalamic-chiasmatic gliomas. (orig.)

  11. High accuracy subwavelength distance measurements: A variable-angle standing-wave total-internal-reflection optical microscope

    International Nuclear Information System (INIS)

    Haynie, A.; Min, T.-J.; Luan, L.; Mu, W.; Ketterson, J. B.

    2009-01-01

    We describe an extension of the total-internal-reflection microscopy technique that permits direct in-plane distance measurements with high accuracy (<10 nm) over a wide range of separations. This high position accuracy arises from the creation of a standing evanescent wave and the ability to sweep the nodal positions (intensity minima of the standing wave) in a controlled manner via both the incident angle and the relative phase of the incoming laser beams. Some control over the vertical resolution is available through the ability to scan the incoming angle and with it the evanescent penetration depth.

  12. High Temperature Integrated Thermoelectric Ststem and Materials

    Energy Technology Data Exchange (ETDEWEB)

    Mike S. H. Chu

    2011-06-06

    The final goal of this project is to produce, by the end of Phase II, an all ceramic high temperature thermoelectric module. Such a module design integrates oxide ceramic n-type, oxide ceramic p-type materials as thermoelectric legs and oxide ceramic conductive material as metalizing connection between n-type and p-type legs. The benefits of this all ceramic module are that it can function at higher temperatures (> 700 C), it is mechanically and functionally more reliable and it can be scaled up to production at lower cost. With this all ceramic module, millions of dollars in savings or in new opportunities recovering waste heat from high temperature processes could be made available. A very attractive application will be to convert exhaust heat from a vehicle to reusable electric energy by a thermoelectric generator (TEG). Phase I activities were focused on evaluating potential n-type and p-type oxide compositions as the thermoelectric legs. More than 40 oxide ceramic powder compositions were made and studied in the laboratory. The compositions were divided into 6 groups representing different material systems. Basic ceramic properties and thermoelectric properties of discs sintered from these powders were measured. Powders with different particles sizes were made to evaluate the effects of particle size reduction on thermoelectric properties. Several powders were submitted to a leading thermoelectric company for complete thermoelectric evaluation. Initial evaluation showed that when samples were sintered by conventional method, they had reasonable values of Seebeck coefficient but very low values of electrical conductivity. Therefore, their power factors (PF) and figure of merits (ZT) were too low to be useful for high temperature thermoelectric applications. An unconventional sintering method, Spark Plasma Sintering (SPS) was determined to produce better thermoelectric properties. Particle size reduction of powders also was found to have some positive benefits

  13. High-accuracy dosimetry study for intensity-modulated radiation therapy(IMRT) commissioning

    International Nuclear Information System (INIS)

    Jeong, Hae Sun

    2010-02-01

    Intensity-modulated radiation therapy (IMRT), an advanced modality of high-precision radiotherapy, allows for an increase in dose to the tumor volume without increasing the dose to nearby critical organs. In order to successfully achieve the treatment, intensive dosimetry with accurate dose verification is necessary. A dosimetry for IMRT, however, is a challenging task due to dosimetric ally unfavorable phenomena such as dramatic changes of the dose at the field boundaries, dis-equilibrium of the electrons, non-uniformity between the detector and the phantom materials, and distortion of scanner-read doses. In the present study, therefore, the LEGO-type multi-purpose dosimetry phantom was developed and used for the studies on dose measurements and correction. Phantom materials for muscle, fat, bone, and lung tissue were selected after considering mass density, atomic composition, effective atomic number, and photon interaction coefficients. The phantom also includes dosimeter holders for several different types of detectors including films, which accommodates a construction of different designs of phantoms as necessary. In order to evaluate its performance, the developed phantom was tested by measuring the point dose and the percent depth dose (PDD) for small size fields under several heterogeneous conditions. However, the measurements with the two types of dosimeter did not agree well for the field sizes less than 1 x 1 cm 2 in muscle and bone, and less than 3 x 3 cm 2 in air cavity. Thus, it was recognized that several studies on small fields dosimetry and correction methods for the calculation with a PMCEPT code are needed. The under-estimated values from the ion chamber were corrected with a convolution method employed to eliminate the volume effect of the chamber. As a result, the discrepancies between the EBT film and the ion chamber measurements were significantly decreased, from 14% to 1% (1 x 1 cm 2 ), 10% to 1% (0.7 x 0.7 cm 2 ), and 42% to 7% (0.5 x 0

  14. High-accuracy dosimetry study for intensity-modulated radiation therapy(IMRT) commissioning

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, Hae Sun

    2010-02-15

    Intensity-modulated radiation therapy (IMRT), an advanced modality of high-precision radiotherapy, allows for an increase in dose to the tumor volume without increasing the dose to nearby critical organs. In order to successfully achieve the treatment, intensive dosimetry with accurate dose verification is necessary. A dosimetry for IMRT, however, is a challenging task due to dosimetric ally unfavorable phenomena such as dramatic changes of the dose at the field boundaries, dis-equilibrium of the electrons, non-uniformity between the detector and the phantom materials, and distortion of scanner-read doses. In the present study, therefore, the LEGO-type multi-purpose dosimetry phantom was developed and used for the studies on dose measurements and correction. Phantom materials for muscle, fat, bone, and lung tissue were selected after considering mass density, atomic composition, effective atomic number, and photon interaction coefficients. The phantom also includes dosimeter holders for several different types of detectors including films, which accommodates a construction of different designs of phantoms as necessary. In order to evaluate its performance, the developed phantom was tested by measuring the point dose and the percent depth dose (PDD) for small size fields under several heterogeneous conditions. However, the measurements with the two types of dosimeter did not agree well for the field sizes less than 1 x 1 cm{sup 2} in muscle and bone, and less than 3 x 3 cm{sup 2} in air cavity. Thus, it was recognized that several studies on small fields dosimetry and correction methods for the calculation with a PMCEPT code are needed. The under-estimated values from the ion chamber were corrected with a convolution method employed to eliminate the volume effect of the chamber. As a result, the discrepancies between the EBT film and the ion chamber measurements were significantly decreased, from 14% to 1% (1 x 1 cm{sup 2}), 10% to 1% (0.7 x 0.7 cm{sup 2}), and 42

  15. High-accuracy and high-sensitivity spectroscopic measurement of dinitrogen pentoxide (N2O5) in an atmospheric simulation chamber using a quantum cascade laser.

    Science.gov (United States)

    Yi, Hongming; Wu, Tao; Lauraguais, Amélie; Semenov, Vladimir; Coeur, Cecile; Cassez, Andy; Fertein, Eric; Gao, Xiaoming; Chen, Weidong

    2017-12-04

    A spectroscopic instrument based on a mid-infrared external cavity quantum cascade laser (EC-QCL) was developed for high-accuracy measurements of dinitrogen pentoxide (N 2 O 5 ) at the ppbv-level. A specific concentration retrieval algorithm was developed to remove, from the broadband absorption spectrum of N 2 O 5 , both etalon fringes resulting from the EC-QCL intrinsic structure and spectral interference lines of H 2 O vapour absorption, which led to a significant improvement in measurement accuracy and detection sensitivity (by a factor of 10), compared to using a traditional algorithm for gas concentration retrieval. The developed EC-QCL-based N 2 O 5 sensing platform was evaluated by real-time tracking N 2 O 5 concentration in its most important nocturnal tropospheric chemical reaction of NO 3 + NO 2 ↔ N 2 O 5 in an atmospheric simulation chamber. Based on an optical absorption path-length of L eff = 70 m, a minimum detection limit of 15 ppbv was achieved with a 25 s integration time and it was down to 3 ppbv in 400 s. The equilibrium rate constant K eq involved in the above chemical reaction was determined with direct concentration measurements using the developed EC-QCL sensing platform, which was in good agreement with the theoretical value deduced from a referenced empirical formula under well controlled experimental conditions. The present work demonstrates the potential and the unique advantage of the use of a modern external cavity quantum cascade laser for applications in direct quantitative measurement of broadband absorption of key molecular species involved in chemical kinetic and climate-change related tropospheric chemistry.

  16. Analysis of the plasmodium falciparum proteome by high-accuracy mass spectrometry

    DEFF Research Database (Denmark)

    Lasonder, Edwin; Ishihama, Yasushi; Andersen, Jens S

    2002-01-01

    -accuracy (average deviation less than 0.02 Da at 1,000 Da) mass spectrometric proteome analysis of selected stages of the human malaria parasite Plasmodium falciparum. The analysis revealed 1,289 proteins of which 714 proteins were identified in asexual blood stages, 931 in gametocytes and 645 in gametes. The last...

  17. High-accuracy interferometric measurements of flatness and parallelism of a step gauge

    CSIR Research Space (South Africa)

    Kruger, OA

    2001-01-01

    Full Text Available The most commonly used method in the calibration of step gauges is the coordinate measuring machine (CMM), equipped with a laser interferometer for the highest accuracy. This paper describes a modification to a length-bar measuring machine...

  18. [Accuracy of placenta accreta prenatal diagnosis by ultrasound and MRI in a high-risk population].

    Science.gov (United States)

    Daney de Marcillac, F; Molière, S; Pinton, A; Weingertner, A-S; Fritz, G; Viville, B; Roedlich, M-N; Gaudineau, A; Sananes, N; Favre, R; Nisand, I; Langer, B

    2016-02-01

    Main objective was to compare accuracy of ultrasonography and MRI for antenatal diagnosis of placenta accreta. Secondary objectives were to specify the most common sonographic and RMI signs associated with diagnosis of placenta accreta. This retrospective study used data collected from all potential cases of placenta accreta (patients with an anterior placenta praevia with history of scarred uterus) admitted from 01/2010 to 12/2014 in a level III maternity unit in Strasbourg, France. High-risk patients beneficiated antenatally from ultrasonography and MRI. Sonographic signs registered were: abnormal placental lacunae, increased vascularity on color Doppler, absence of the retroplacental clear space, interrupted bladder line. MRI signs registered were: abnormal uterine bulging, intraplacental bands of low signal intensity on T2-weighted images, increased vascularity, heterogeneous signal of the placenta on T2-weighed, interrupted bladder line, protrusion of the placenta into the cervix. Diagnosis of placenta accreta was confirmed histologically after hysterectomy or clinically in case of successful conservative treatment. Twenty-two potential cases of placenta accreta were referred to our center and underwent both ultrasonography and MRI. All cases of placenta accreta had a placenta praevia associated with history of scarred uterus. Sensibility and specificity for ultrasonography were, respectively, 0.92 and 0.67, for MRI 0.84 and 0.78 without significant difference (p>0.05). The most relevant signs associated with diagnosis of placenta accreta in ultrasonography were increased vascularity on color Doppler (sensibility 0.85/specificity 0.78), abnormal placental lacunae (sensibility 0.92/specificity 0.55) and loss of retroplacental clear space (sensibility 0.76/specificity 1.0). The most relevant signs in MRI were: abnormal uterine bulging (sensitivity 0.92/specificity 0.89), dark intraplacental bands on T2-weighted images (sensitivity 0.83/specificity 0.80) or

  19. Automatic camera to laser calibration for high accuracy mobile mapping systems using INS

    Science.gov (United States)

    Goeman, Werner; Douterloigne, Koen; Gautama, Sidharta

    2013-09-01

    A mobile mapping system (MMS) is a mobile multi-sensor platform developed by the geoinformation community to support the acquisition of huge amounts of geodata in the form of georeferenced high resolution images and dense laser clouds. Since data fusion and data integration techniques are increasingly able to combine the complementary strengths of different sensor types, the external calibration of a camera to a laser scanner is a common pre-requisite on today's mobile platforms. The methods of calibration, nevertheless, are often relatively poorly documented, are almost always time-consuming, demand expert knowledge and often require a carefully constructed calibration environment. A new methodology is studied and explored to provide a high quality external calibration for a pinhole camera to a laser scanner which is automatic, easy to perform, robust and foolproof. The method presented here, uses a portable, standard ranging pole which needs to be positioned on a known ground control point. For calibration, a well studied absolute orientation problem needs to be solved. In many cases, the camera and laser sensor are calibrated in relation to the INS system. Therefore, the transformation from camera to laser contains the cumulated error of each sensor in relation to the INS. Here, the calibration of the camera is performed in relation to the laser frame using the time synchronization between the sensors for data association. In this study, the use of the inertial relative movement will be explored to collect more useful calibration data. This results in a better intersensor calibration allowing better coloring of the clouds and a more accurate depth mask for images, especially on the edges of objects in the scene.

  20. Accuracy of High-Resolution MRI with Lumen Distention in Rectal Cancer Staging and Circumferential Margin Involvement Prediction

    International Nuclear Information System (INIS)

    Iannicelli, Elsa; Di Renzo, Sara; Ferri, Mario; Pilozzi, Emanuela; Di Girolamo, Marco; Sapori, Alessandra; Ziparo, Vincenzo; David, Vincenzo

    2014-01-01

    To evaluate the accuracy of magnetic resonance imaging (MRI) with lumen distention for rectal cancer staging and circumferential resection margin (CRM) involvement prediction. Seventy-three patients with primary rectal cancer underwent high-resolution MRI with a phased-array coil performed using 60-80 mL room air rectal distention, 1-3 weeks before surgery. MRI results were compared to postoperative histopathological findings. The overall MRI T staging accuracy was calculated. CRM involvement prediction and the N staging, the accuracy, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were assessed for each T stage. The agreement between MRI and histological results was assessed using weighted-kappa statistics. The overall MRI accuracy for T staging was 93.6% (k = 0.85). The accuracy, sensitivity, specificity, PPV and NPV for each T stage were as follows: 91.8%, 86.2%, 95.5%, 92.6% and 91.3% for the group ≤ T2; 90.4%, 94.6%, 86.1%, 87.5% and 94% for T3; 98,6%, 85.7%, 100%, 100% and 98.5% for T4, respectively. The predictive CRM accuracy was 94.5% (k = 0.86); the sensitivity, specificity, PPV and NPV were 89.5%, 96.3%, 89.5%, and 96.3% respectively. The N staging accuracy was 68.49% (k = 0.4). MRI performed with rectal lumen distention has proved to be an effective technique both for rectal cancer staging and involved CRM predicting

  1. Accuracy of High-Resolution MRI with Lumen Distention in Rectal Cancer Staging and Circumferential Margin Involvement Prediction

    Energy Technology Data Exchange (ETDEWEB)

    Iannicelli, Elsa; Di Renzo, Sara [Radiology Institute, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant' Andrea Hospital, Rome 00189 (Italy); Department of Surgical and Medical Sciences and Translational Medicine, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant' Andrea Hospital, Rome 00189 (Italy); Ferri, Mario [Department of Surgical and Medical Sciences and Translational Medicine, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant' Andrea Hospital, Rome 00189 (Italy); Pilozzi, Emanuela [Department of Clinical and Molecular Sciences, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant' Andrea Hospital, Rome 00189 (Italy); Di Girolamo, Marco; Sapori, Alessandra [Radiology Institute, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant' Andrea Hospital, Rome 00189 (Italy); Department of Surgical and Medical Sciences and Translational Medicine, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant' Andrea Hospital, Rome 00189 (Italy); Ziparo, Vincenzo [Department of Surgical and Medical Sciences and Translational Medicine, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant' Andrea Hospital, Rome 00189 (Italy); David, Vincenzo [Radiology Institute, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant' Andrea Hospital, Rome 00189 (Italy); Department of Surgical and Medical Sciences and Translational Medicine, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant' Andrea Hospital, Rome 00189 (Italy)

    2014-07-01

    To evaluate the accuracy of magnetic resonance imaging (MRI) with lumen distention for rectal cancer staging and circumferential resection margin (CRM) involvement prediction. Seventy-three patients with primary rectal cancer underwent high-resolution MRI with a phased-array coil performed using 60-80 mL room air rectal distention, 1-3 weeks before surgery. MRI results were compared to postoperative histopathological findings. The overall MRI T staging accuracy was calculated. CRM involvement prediction and the N staging, the accuracy, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were assessed for each T stage. The agreement between MRI and histological results was assessed using weighted-kappa statistics. The overall MRI accuracy for T staging was 93.6% (k = 0.85). The accuracy, sensitivity, specificity, PPV and NPV for each T stage were as follows: 91.8%, 86.2%, 95.5%, 92.6% and 91.3% for the group ≤ T2; 90.4%, 94.6%, 86.1%, 87.5% and 94% for T3; 98,6%, 85.7%, 100%, 100% and 98.5% for T4, respectively. The predictive CRM accuracy was 94.5% (k = 0.86); the sensitivity, specificity, PPV and NPV were 89.5%, 96.3%, 89.5%, and 96.3% respectively. The N staging accuracy was 68.49% (k = 0.4). MRI performed with rectal lumen distention has proved to be an effective technique both for rectal cancer staging and involved CRM predicting.

  2. High-frequency analog integrated circuit design

    CERN Document Server

    1995-01-01

    To learn more about designing analog integrated circuits (ICs) at microwave frequencies using GaAs materials, turn to this text and reference. It addresses GaAs MESFET-based IC processing. Describes the newfound ability to apply silicon analog design techniques to reliable GaAs materials and devices which, until now, was only available through technical papers scattered throughout hundred of articles in dozens of professional journals.

  3. SFOL Pulse: A High Accuracy DME Pulse for Alternative Aircraft Position and Navigation

    Directory of Open Access Journals (Sweden)

    Euiho Kim

    2017-09-01

    Full Text Available In the Federal Aviation Administration’s (FAA performance based navigation strategy announced in 2016, the FAA stated that it would retain and expand the Distance Measuring Equipment (DME infrastructure to ensure resilient aircraft navigation capability during the event of a Global Navigation Satellite System (GNSS outage. However, the main drawback of the DME as a GNSS back up system is that it requires a significant expansion of the current DME ground infrastructure due to its poor distance measuring accuracy over 100 m. The paper introduces a method to improve DME distance measuring accuracy by using a new DME pulse shape. The proposed pulse shape was developed by using Genetic Algorithms and is less susceptible to multipath effects so that the ranging error reduces by 36.0–77.3% when compared to the Gaussian and Smoothed Concave Polygon DME pulses, depending on noise environment.

  4. Automatic J–A Model Parameter Tuning Algorithm for High Accuracy Inrush Current Simulation

    Directory of Open Access Journals (Sweden)

    Xishan Wen

    2017-04-01

    Full Text Available Inrush current simulation plays an important role in many tasks of the power system, such as power transformer protection. However, the accuracy of the inrush current simulation can hardly be ensured. In this paper, a Jiles–Atherton (J–A theory based model is proposed to simulate the inrush current of power transformers. The characteristics of the inrush current curve are analyzed and results show that the entire inrush current curve can be well featured by the crest value of the first two cycles. With comprehensive consideration of both of the features of the inrush current curve and the J–A parameters, an automatic J–A parameter estimation algorithm is proposed. The proposed algorithm can obtain more reasonable J–A parameters, which improve the accuracy of simulation. Experimental results have verified the efficiency of the proposed algorithm.

  5. [Method for evaluating the positional accuracy of a six-degrees-of-freedom radiotherapy couch using high definition digital cameras].

    Science.gov (United States)

    Takemura, Akihiro; Ueda, Shinichi; Noto, Kimiya; Kurata, Yuichi; Shoji, Saori

    2011-01-01

    In this study, we proposed and evaluated a positional accuracy assessment method with two high-resolution digital cameras for add-on six-degrees-of-freedom radiotherapy (6D) couches. Two high resolution digital cameras (D5000, Nikon Co.) were used in this accuracy assessment method. These cameras were placed on two orthogonal axes of a linear accelerator (LINAC) coordinate system and focused on the isocenter of the LINAC. Pictures of a needle that was fixed on the 6D couch were taken by the cameras during couch motions of translation and rotation of each axis. The coordinates of the needle in the pictures were obtained using manual measurement, and the coordinate error of the needle was calculated. The accuracy of a HexaPOD evo (Elekta AB, Sweden) was evaluated using this method. All of the mean values of the X, Y, and Z coordinate errors in the translation tests were within ±0.1 mm. However, the standard deviation of the Z coordinate errors in the Z translation test was 0.24 mm, which is higher than the others. In the X rotation test, we found that the X coordinate of the rotational origin of the 6D couch was shifted. We proposed an accuracy assessment method for a 6D couch. The method was able to evaluate the accuracy of the motion of only the 6D couch and revealed the deviation of the origin of the couch rotation. This accuracy assessment method is effective for evaluating add-on 6D couch positioning.

  6. Thermal Stability of Magnetic Compass Sensor for High Accuracy Positioning Applications

    OpenAIRE

    Van-Tang PHAM; Dinh-Chinh NGUYEN; Quang-Huy TRAN; Duc-Trinh CHU; Duc-Tan TRAN

    2015-01-01

    Using magnetic compass sensors in angle measurements have a wide area of application such as positioning, robot, landslide, etc. However, one of the most phenomenal that affects to the accuracy of the magnetic compass sensor is the temperature. This paper presents two thermal stability schemes for improving performance of a magnetic compass sensor. The first scheme uses the feedforward structure to adjust the angle output of the compass sensor adapt to the variation of the temperature. The se...

  7. A High-Accuracy Linear Conservative Difference Scheme for Rosenau-RLW Equation

    Directory of Open Access Journals (Sweden)

    Jinsong Hu

    2013-01-01

    Full Text Available We study the initial-boundary value problem for Rosenau-RLW equation. We propose a three-level linear finite difference scheme, which has the theoretical accuracy of Oτ2+h4. The scheme simulates two conservative properties of original problem well. The existence, uniqueness of difference solution, and a priori estimates in infinite norm are obtained. Furthermore, we analyze the convergence and stability of the scheme by energy method. At last, numerical experiments demonstrate the theoretical results.

  8. New perspectives for high accuracy SLR with second generation geodesic satellites

    Science.gov (United States)

    Lund, Glenn

    1993-01-01

    This paper reports on the accuracy limitations imposed by geodesic satellite signatures, and on the potential for achieving millimetric performances by means of alternative satellite concepts and an optimized 2-color system tradeoff. Long distance laser ranging, when performed between a ground (emitter/receiver) station and a distant geodesic satellite, is now reputed to enable short arc trajectory determinations to be achieved with an accuracy of 1 to 2 centimeters. This state-of-the-art accuracy is limited principally by the uncertainties inherent to single-color atmospheric path length correction. Motivated by the study of phenomena such as postglacial rebound, and the detailed analysis of small-scale volcanic and strain deformations, the drive towards millimetric accuracies will inevitably be felt. With the advent of short pulse (less than 50 ps) dual wavelength ranging, combined with adequate detection equipment (such as a fast-scanning streak camera or ultra-fast solid-state detectors) the atmospheric uncertainty could potentially be reduced to the level of a few millimeters, thus, exposing other less significant error contributions, of which by far the most significant will then be the morphology of the retroreflector satellites themselves. Existing geodesic satellites are simply dense spheres, several 10's of cm in diameter, encrusted with a large number (426 in the case of LAGEOS) of small cube-corner reflectors. A single incident pulse, thus, results in a significant number of randomly phased, quasi-simultaneous return pulses. These combine coherently at the receiver to produce a convolved interference waveform which cannot, on a shot to shot basis, be accurately and unambiguously correlated to the satellite center of mass. This paper proposes alternative geodesic satellite concepts, based on the use of a very small number of cube-corner retroreflectors, in which the above difficulties are eliminated while ensuring, for a given emitted pulse, the return

  9. A high-accuracy optical linear algebra processor for finite element applications

    Science.gov (United States)

    Casasent, D.; Taylor, B. K.

    1984-01-01

    Optical linear processors are computationally efficient computers for solving matrix-matrix and matrix-vector oriented problems. Optical system errors limit their dynamic range to 30-40 dB, which limits their accuray to 9-12 bits. Large problems, such as the finite element problem in structural mechanics (with tens or hundreds of thousands of variables) which can exploit the speed of optical processors, require the 32 bit accuracy obtainable from digital machines. To obtain this required 32 bit accuracy with an optical processor, the data can be digitally encoded, thereby reducing the dynamic range requirements of the optical system (i.e., decreasing the effect of optical errors on the data) while providing increased accuracy. This report describes a new digitally encoded optical linear algebra processor architecture for solving finite element and banded matrix-vector problems. A linear static plate bending case study is described which quantities the processor requirements. Multiplication by digital convolution is explained, and the digitally encoded optical processor architecture is advanced.

  10. High Accuracy Human Activity Recognition Based on Sparse Locality Preserving Projections.

    Science.gov (United States)

    Zhu, Xiangbin; Qiu, Huiling

    2016-01-01

    Human activity recognition(HAR) from the temporal streams of sensory data has been applied to many fields, such as healthcare services, intelligent environments and cyber security. However, the classification accuracy of most existed methods is not enough in some applications, especially for healthcare services. In order to improving accuracy, it is necessary to develop a novel method which will take full account of the intrinsic sequential characteristics for time-series sensory data. Moreover, each human activity may has correlated feature relationship at different levels. Therefore, in this paper, we propose a three-stage continuous hidden Markov model (TSCHMM) approach to recognize human activities. The proposed method contains coarse, fine and accurate classification. The feature reduction is an important step in classification processing. In this paper, sparse locality preserving projections (SpLPP) is exploited to determine the optimal feature subsets for accurate classification of the stationary-activity data. It can extract more discriminative activities features from the sensor data compared with locality preserving projections. Furthermore, all of the gyro-based features are used for accurate classification of the moving data. Compared with other methods, our method uses significantly less number of features, and the over-all accuracy has been obviously improved.

  11. High Accuracy Human Activity Recognition Based on Sparse Locality Preserving Projections.

    Directory of Open Access Journals (Sweden)

    Xiangbin Zhu

    Full Text Available Human activity recognition(HAR from the temporal streams of sensory data has been applied to many fields, such as healthcare services, intelligent environments and cyber security. However, the classification accuracy of most existed methods is not enough in some applications, especially for healthcare services. In order to improving accuracy, it is necessary to develop a novel method which will take full account of the intrinsic sequential characteristics for time-series sensory data. Moreover, each human activity may has correlated feature relationship at different levels. Therefore, in this paper, we propose a three-stage continuous hidden Markov model (TSCHMM approach to recognize human activities. The proposed method contains coarse, fine and accurate classification. The feature reduction is an important step in classification processing. In this paper, sparse locality preserving projections (SpLPP is exploited to determine the optimal feature subsets for accurate classification of the stationary-activity data. It can extract more discriminative activities features from the sensor data compared with locality preserving projections. Furthermore, all of the gyro-based features are used for accurate classification of the moving data. Compared with other methods, our method uses significantly less number of features, and the over-all accuracy has been obviously improved.

  12. High accuracy microwave frequency measurement based on single-drive dual-parallel Mach-Zehnder modulator

    DEFF Research Database (Denmark)

    Zhao, Ying; Pang, Xiaodan; Deng, Lei

    2011-01-01

    A novel approach for broadband microwave frequency measurement by employing a single-drive dual-parallel Mach-Zehnder modulator is proposed and experimentally demonstrated. Based on bias manipulations of the modulator, conventional frequency-to-power mapping technique is developed by performing a...... 10−3 relative error. This high accuracy frequency measurement technique is a promising candidate for high-speed electronic warfare and defense applications....

  13. Strategy for high-accuracy-and-precision retrieval of atmospheric methane from the mid-infrared FTIR network

    Directory of Open Access Journals (Sweden)

    R. Sussmann

    2011-09-01

    Full Text Available We present a strategy (MIR-GBM v1.0 for the retrieval of column-averaged dry-air mole fractions of methane (XCH4 with a precision <0.3% (1-σ diurnal variation, 7-min integration and a seasonal bias <0.14% from mid-infrared ground-based solar FTIR measurements of the Network for the Detection of Atmospheric Composition Change (NDACC, comprising 22 FTIR stations. This makes NDACC methane data useful for satellite validation and for the inversion of regional-scale sources and sinks in addition to long-term trend analysis. Such retrievals complement the high accuracy and precision near-infrared observations of the younger Total Carbon Column Observing Network (TCCON with time series dating back 15 years or so before TCCON operations began.

    MIR-GBM v1.0 is using HITRAN 2000 (including the 2001 update release and 3 spectral micro windows (2613.70–2615.40 cm−1, 2835.50–2835.80 cm−1, 2921.00–2921.60 cm−1. A first-order Tikhonov constraint is applied to the state vector given in units of per cent of volume mixing ratio. It is tuned to achieve minimum diurnal variation without damping seasonality. Final quality selection of the retrievals uses a threshold for the goodness of fit (χ2 < 1 as well as for the ratio of root-mean-square spectral noise and information content (<0.15%. Column-averaged dry-air mole fractions are calculated using the retrieved methane profiles and four-times-daily pressure-temperature-humidity profiles from National Center for Environmental Prediction (NCEP interpolated to the time of measurement.

    MIR-GBM v1.0 is the optimum of 24 tested retrieval strategies (8 different spectral micro-window selections, 3 spectroscopic line lists: HITRAN 2000, 2004, 2008. Dominant errors of the non-optimum retrieval strategies are systematic HDO/H2O-CH4 interference errors leading to a seasonal bias up to ≈5%. Therefore interference

  14. Accuracy and calibration of integrated radiation output indicators in diagnostic radiology: A report of the AAPM Imaging Physics Committee Task Group 190

    International Nuclear Information System (INIS)

    Lin, Pei-Jan P.; Schueler, Beth A.; Balter, Stephen; Strauss, Keith J.; Wunderle, Kevin A.; LaFrance, M. Terry; Kim, Don-Soo; Behrman, Richard H.; Shepard, S. Jeff; Bercha, Ishtiaq H.

    2015-01-01

    Due to the proliferation of disciplines employing fluoroscopy as their primary imaging tool and the prolonged extensive use of fluoroscopy in interventional and cardiovascular angiography procedures, “dose-area-product” (DAP) meters were installed to monitor and record the radiation dose delivered to patients. In some cases, the radiation dose or the output value is calculated, rather than measured, using the pertinent radiological parameters and geometrical information. The AAPM Task Group 190 (TG-190) was established to evaluate the accuracy of the DAP meter in 2008. Since then, the term “DAP-meter” has been revised to air kerma-area product (KAP) meter. The charge of TG 190 (Accuracy and Calibration of Integrated Radiation Output Indicators in Diagnostic Radiology) has also been realigned to investigate the “Accuracy and Calibration of Integrated Radiation Output Indicators” which is reflected in the title of the task group, to include situations where the KAP may be acquired with or without the presence of a physical “meter.” To accomplish this goal, validation test protocols were developed to compare the displayed radiation output value to an external measurement. These test protocols were applied to a number of clinical systems to collect information on the accuracy of dose display values in the field

  15. Accuracy and calibration of integrated radiation output indicators in diagnostic radiology: A report of the AAPM Imaging Physics Committee Task Group 190

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Pei-Jan P., E-mail: Pei-Jan.Lin@vcuhealth.org [Virginia Commonwealth University Medical Center, Richmond, Virginia 23298 (United States); Schueler, Beth A. [Mayo Clinic, Rochester, Minnesota 55905 (United States); Balter, Stephen [Columbia University Medical Center, New York, New York 10032 (United States); Strauss, Keith J. [Children’s Hospital Medical Center, Cincinnati, Ohio 45229 (United States); Wunderle, Kevin A. [Cleveland Clinic Foundation, Cleveland, Ohio 44195 (United States); LaFrance, M. Terry [Baystate Health Systems, Inc., Springfield, Massachusetts 01199 (United States); Kim, Don-Soo [Children’s Hospital Boston, Boston, Massachusetts 02115 (United States); Behrman, Richard H. [Boston University Medical Center, Boston, Massachusetts 02118 (United States); Shepard, S. Jeff [University of Texas MD Anderson Cancer Center, Houston, Texas 77096 (United States); Bercha, Ishtiaq H. [Children’s Hospital Colorado, Aurora, Colorado 80045 (United States)

    2015-12-15

    Due to the proliferation of disciplines employing fluoroscopy as their primary imaging tool and the prolonged extensive use of fluoroscopy in interventional and cardiovascular angiography procedures, “dose-area-product” (DAP) meters were installed to monitor and record the radiation dose delivered to patients. In some cases, the radiation dose or the output value is calculated, rather than measured, using the pertinent radiological parameters and geometrical information. The AAPM Task Group 190 (TG-190) was established to evaluate the accuracy of the DAP meter in 2008. Since then, the term “DAP-meter” has been revised to air kerma-area product (KAP) meter. The charge of TG 190 (Accuracy and Calibration of Integrated Radiation Output Indicators in Diagnostic Radiology) has also been realigned to investigate the “Accuracy and Calibration of Integrated Radiation Output Indicators” which is reflected in the title of the task group, to include situations where the KAP may be acquired with or without the presence of a physical “meter.” To accomplish this goal, validation test protocols were developed to compare the displayed radiation output value to an external measurement. These test protocols were applied to a number of clinical systems to collect information on the accuracy of dose display values in the field.

  16. THE EFFECT OF MODERATE AND HIGH-INTENSITY FATIGUE ON GROUNDSTROKE ACCURACY IN EXPERT AND NON-EXPERT TENNIS PLAYERS

    Directory of Open Access Journals (Sweden)

    Mark Lyons

    2013-06-01

    Full Text Available Exploring the effects of fatigue on skilled performance in tennis presents a significant challenge to the researcher with respect to ecological validity. This study examined the effects of moderate and high-intensity fatigue on groundstroke accuracy in expert and non-expert tennis players. The research also explored whether the effects of fatigue are the same regardless of gender and player's achievement motivation characteristics. 13 expert (7 male, 6 female and 17 non-expert (13 male, 4 female tennis players participated in the study. Groundstroke accuracy was assessed using the modified Loughborough Tennis Skills Test. Fatigue was induced using the Loughborough Intermittent Tennis Test with moderate (70% and high-intensities (90% set as a percentage of peak heart rate (attained during a tennis-specific maximal hitting sprint test. Ratings of perceived exertion were used as an adjunct to the monitoring of heart rate. Achievement goal indicators for each player were assessed using the 2 x 2 Achievement Goals Questionnaire for Sport in an effort to examine if this personality characteristic provides insight into how players perform under moderate and high-intensity fatigue conditions. A series of mixed ANOVA's revealed significant fatigue effects on groundstroke accuracy regardless of expertise. The expert players however, maintained better groundstroke accuracy across all conditions compared to the novice players. Nevertheless, in both groups, performance following high-intensity fatigue deteriorated compared to performance at rest and performance while moderately fatigued. Groundstroke accuracy under moderate levels of fatigue was equivalent to that at rest. Fatigue effects were also similar regardless of gender. No fatigue by expertise, or fatigue by gender interactions were found. Fatigue effects were also equivalent regardless of player's achievement goal indicators. Future research is required to explore the effects of fatigue on

  17. High accuracy prediction of beta-turns and their types using propensities and multiple alignments.

    Science.gov (United States)

    Fuchs, Patrick F J; Alix, Alain J P

    2005-06-01

    We have developed a method that predicts both the presence and the type of beta-turns, using a straightforward approach based on propensities and multiple alignments. The propensities were calculated classically, but the way to use them for prediction was completely new: starting from a tetrapeptide sequence on which one wants to evaluate the presence of a beta-turn, the propensity for a given residue is modified by taking into account all the residues present in the multiple alignment at this position. The evaluation of a score is then done by weighting these propensities by the use of Position-specific score matrices generated by PSI-BLAST. The introduction of secondary structure information predicted by PSIPRED or SSPRO2 as well as taking into account the flanking residues around the tetrapeptide improved the accuracy greatly. This latter evaluated on a database of 426 reference proteins (previously used on other studies) by a sevenfold crossvalidation gave very good results with a Matthews Correlation Coefficient (MCC) of 0.42 and an overall prediction accuracy of 74.8%; this places our method among the best ones. A jackknife test was also done, which gave results within the same range. This shows that it is possible to reach neural networks accuracy with considerably less computional cost and complexity. Furthermore, propensities remain excellent descriptors of amino acid tendencies to belong to beta-turns, which can be useful for peptide or protein engineering and design. For beta-turn type prediction, we reached the best accuracy ever published in terms of MCC (except for the irregular type IV) in the range of 0.25-0.30 for types I, II, and I' and 0.13-0.15 for types VIII, II', and IV. To our knowledge, our method is the only one available on the Web that predicts types I' and II'. The accuracy evaluated on two larger databases of 547 and 823 proteins was not improved significantly. All of this was implemented into a Web server called COUDES (French acronym

  18. Progress in the High Level Trigger Integration

    CERN Multimedia

    Cristobal Padilla

    2007-01-01

    During the week from March 19th to March 23rd, the DAQ/HLT group performed another of its technical runs. On this occasion the focus was on integrating the Level 2 and Event Filter triggers, with a much fuller integration of HLT components than had been done previously. For the first time this included complete trigger slices, with a menu to run the selection algorithms for muons, electrons, jets and taus at the Level-2 and Event Filter levels. This Technical run again used the "Pre-Series" system (a vertical slice prototype of the DAQ/HLT system, see the ATLAS e-news January issue for details). Simulated events, provided by our colleagues working in the streaming tests, were pre-loaded into the ROS (Read Out System) nodes. These are the PC's where the data from the detector is stored after coming out of the front-end electronics, the "first part of the TDAQ system" and the interface to the detectors. These events used a realistic beam interaction mixture and had been subjected to a Level-1 selection. The...

  19. Analysis of high accuracy, quantitative proteomics data in the MaxQB database.

    Science.gov (United States)

    Schaab, Christoph; Geiger, Tamar; Stoehr, Gabriele; Cox, Juergen; Mann, Matthias

    2012-03-01

    MS-based proteomics generates rapidly increasing amounts of precise and quantitative information. Analysis of individual proteomic experiments has made great strides, but the crucial ability to compare and store information across different proteome measurements still presents many challenges. For example, it has been difficult to avoid contamination of databases with low quality peptide identifications, to control for the inflation in false positive identifications when combining data sets, and to integrate quantitative data. Although, for example, the contamination with low quality identifications has been addressed by joint analysis of deposited raw data in some public repositories, we reasoned that there should be a role for a database specifically designed for high resolution and quantitative data. Here we describe a novel database termed MaxQB that stores and displays collections of large proteomics projects and allows joint analysis and comparison. We demonstrate the analysis tools of MaxQB using proteome data of 11 different human cell lines and 28 mouse tissues. The database-wide false discovery rate is controlled by adjusting the project specific cutoff scores for the combined data sets. The 11 cell line proteomes together identify proteins expressed from more than half of all human genes. For each protein of interest, expression levels estimated by label-free quantification can be visualized across the cell lines. Similarly, the expression rank order and estimated amount of each protein within each proteome are plotted. We used MaxQB to calculate the signal reproducibility of the detected peptides for the same proteins across different proteomes. Spearman rank correlation between peptide intensity and detection probability of identified proteins was greater than 0.8 for 64% of the proteome, whereas a minority of proteins have negative correlation. This information can be used to pinpoint false protein identifications, independently of peptide database

  20. Direct integration multiple collision integral transport analysis method for high energy fusion neutronics

    International Nuclear Information System (INIS)

    Koch, K.R.

    1985-01-01

    A new analysis method specially suited for the inherent difficulties of fusion neutronics was developed to provide detailed studies of the fusion neutron transport physics. These studies should provide a better understanding of the limitations and accuracies of typical fusion neutronics calculations. The new analysis method is based on the direct integration of the integral form of the neutron transport equation and employs a continuous energy formulation with the exact treatment of the energy angle kinematics of the scattering process. In addition, the overall solution is analyzed in terms of uncollided, once-collided, and multi-collided solution components based on a multiple collision treatment. Furthermore, the numerical evaluations of integrals use quadrature schemes that are based on the actual dependencies exhibited in the integrands. The new DITRAN computer code was developed on the Cyber 205 vector supercomputer to implement this direct integration multiple-collision fusion neutronics analysis. Three representative fusion reactor models were devised and the solutions to these problems were studied to provide suitable choices for the numerical quadrature orders as well as the discretized solution grid and to understand the limitations of the new analysis method. As further verification and as a first step in assessing the accuracy of existing fusion-neutronics calculations, solutions obtained using the new analysis method were compared to typical multigroup discrete ordinates calculations

  1. High accuracy navigation information estimation for inertial system using the multi-model EKF fusing adams explicit formula applied to underwater gliders.

    Science.gov (United States)

    Huang, Haoqian; Chen, Xiyuan; Zhang, Bo; Wang, Jian

    2017-01-01

    The underwater navigation system, mainly consisting of MEMS inertial sensors, is a key technology for the wide application of underwater gliders and plays an important role in achieving high accuracy navigation and positioning for a long time of period. However, the navigation errors will accumulate over time because of the inherent errors of inertial sensors, especially for MEMS grade IMU (Inertial Measurement Unit) generally used in gliders. The dead reckoning module is added to compensate the errors. In the complicated underwater environment, the performance of MEMS sensors is degraded sharply and the errors will become much larger. It is difficult to establish the accurate and fixed error model for the inertial sensor. Therefore, it is very hard to improve the accuracy of navigation information calculated by sensors. In order to solve the problem mentioned, the more suitable filter which integrates the multi-model method with an EKF approach can be designed according to different error models to give the optimal estimation for the state. The key parameters of error models can be used to determine the corresponding filter. The Adams explicit formula which has an advantage of high precision prediction is simultaneously fused into the above filter to achieve the much more improvement in attitudes estimation accuracy. The proposed algorithm has been proved through theory analyses and has been tested by both vehicle experiments and lake trials. Results show that the proposed method has better accuracy and effectiveness in terms of attitudes estimation compared with other methods mentioned in the paper for inertial navigation applied to underwater gliders. Copyright © 2016 ISA. Published by Elsevier Ltd. All rights reserved.

  2. Accuracy of applicator tip reconstruction in MRI-guided interstitial 192Ir-high-dose-rate brachytherapy of liver tumors

    International Nuclear Information System (INIS)

    Wybranski, Christian; Eberhardt, Benjamin; Fischbach, Katharina; Fischbach, Frank; Walke, Mathias; Hass, Peter; Röhl, Friedrich-Wilhelm; Kosiek, Ortrud; Kaiser, Mandy; Pech, Maciej; Lüdemann, Lutz; Ricke, Jens

    2015-01-01

    Background and purpose: To evaluate the reconstruction accuracy of brachytherapy (BT) applicators tips in vitro and in vivo in MRI-guided 192 Ir-high-dose-rate (HDR)-BT of inoperable liver tumors. Materials and methods: Reconstruction accuracy of plastic BT applicators, visualized by nitinol inserts, was assessed in MRI phantom measurements and in MRI 192 Ir-HDR-BT treatment planning datasets of 45 patients employing CT co-registration and vector decomposition. Conspicuity, short-term dislocation, and reconstruction errors were assessed in the clinical data. The clinical effect of applicator reconstruction accuracy was determined in follow-up MRI data. Results: Applicator reconstruction accuracy was 1.6 ± 0.5 mm in the phantom measurements. In the clinical MRI datasets applicator conspicuity was rated good/optimal in ⩾72% of cases. 16/129 applicators showed not time dependent deviation in between MRI/CT acquisition (p > 0.1). Reconstruction accuracy was 5.5 ± 2.8 mm, and the average image co-registration error was 3.1 ± 0.9 mm. Vector decomposition revealed no preferred direction of reconstruction errors. In the follow-up data deviation of planned dose distribution and irradiation effect was 6.9 ± 3.3 mm matching the mean co-registration error (6.5 ± 2.5 mm; p > 0.1). Conclusion: Applicator reconstruction accuracy in vitro conforms to AAPM TG 56 standard. Nitinol-inserts are feasible for applicator visualization and yield good conspicuity in MRI treatment planning data. No preferred direction of reconstruction errors were found in vivo

  3. Horizontal Positional Accuracy of Google Earth’s High-Resolution Imagery Archive

    Directory of Open Access Journals (Sweden)

    David Potere

    2008-12-01

    Full Text Available Google Earth now hosts high-resolution imagery that spans twenty percent of the Earth’s landmass and more than a third of the human population. This contemporary highresolution archive represents a significant, rapidly expanding, cost-free and largely unexploited resource for scientific inquiry. To increase the scientific utility of this archive, we address horizontal positional accuracy (georegistration by comparing Google Earth with Landsat GeoCover scenes over a global sample of 436 control points located in 109 cities worldwide. Landsat GeoCover is an orthorectified product with known absolute positional accuracy of less than 50 meters root-mean-squared error (RMSE. Relative to Landsat GeoCover, the 436 Google Earth control points have a positional accuracy of 39.7 meters RMSE (error magnitudes range from 0.4 to 171.6 meters. The control points derived from satellite imagery have an accuracy of 22.8 meters RMSE, which is significantly more accurate than the 48 control-points based on aerial photography (41.3 meters RMSE; t-test p-value < 0.01. The accuracy of control points in more-developed countries is 24.1 meters RMSE, which is significantly more accurate than the control points in developing countries (44.4 meters RMSE; t-test p-value < 0.01. These findings indicate that Google Earth highresolution imagery has a horizontal positional accuracy that is sufficient for assessing moderate-resolution remote sensing products across most of the world’s peri-urban areas.

  4. High capacity photonic integrated switching circuits

    NARCIS (Netherlands)

    Albores Mejia, A.

    2011-01-01

    As the demand for high-capacity data transfer keeps increasing in high performance computing and in a broader range of system area networking environments; reconfiguring the strained networks at ever faster speeds with larger volumes of traffic has become a huge challenge. Formidable bottlenecks

  5. Geometric Accuracy Investigations of SEVIRI High Resolution Visible (HRV Level 1.5 Imagery

    Directory of Open Access Journals (Sweden)

    Sultan Kocaman Aksakal

    2013-05-01

    Full Text Available GCOS (Global Climate Observing System is a long-term program for monitoring the climate, detecting the changes, and assessing their impacts. Remote sensing techniques are being increasingly used for climate-related measurements. Imagery of the SEVIRI instrument on board of the European geostationary satellites Meteosat-8 and Meteosat-9 are often used for the estimation of essential climate variables. In a joint project between the Swiss GCOS Office and ETH Zurich, geometric accuracy and temporal stability of 1-km resolution HRV channel imagery of SEVIRI have been evaluated over Switzerland. A set of tools and algorithms has been developed for the investigations. Statistical analysis and blunder detection have been integrated in the process for robust evaluation. The relative accuracy is evaluated by tracking large numbers of feature points in consecutive HRV images taken at 15-minute intervals. For the absolute accuracy evaluation, lakes in Switzerland and surroundings are used as reference. 20 lakes digitized from Landsat orthophotos are transformed into HRV images and matched via 2D translation terms at sub-pixel level. The algorithms are tested using HRV images taken on 24 days in 2008 (2 days per month. The results show that 2D shifts that are up to 8 pixels are present both in relative and absolute terms.

  6. High accuracy mapping with cartographic assessment for a fixed-wing remotely piloted aircraft system

    Science.gov (United States)

    Alves Júnior, Leomar Rufino; Ferreira, Manuel Eduardo; Côrtes, João Batista Ramos; de Castro Jorge, Lúcio André

    2018-01-01

    The lack of updated maps on large scale representations has encouraged the use of remotely piloted aircraft systems (RPAS) to generate maps for a wide range of professionals. However, some questions arise: do the orthomosaics generated by these systems have the cartographic precision required to use them? Which problems can be identified in stitching orthophotos to generate orthomosaics? To answer these questions, an aerophotogrammetric survey was conducted in an environmental conservation unit in the city of Goiânia. The flight plan was set up using the E-motion software, provided by Sensefly-a Swiss manufacturer of the RPAS Swinglet CAM used in this work. The camera installed in the RPAS was the Canon IXUS 220 HS, with the number of pixels in the sensor array of 12.1 megapixel, complementary metal oxide semiconductor 1 ∶ 2.3 ? (4000 × 3000 pixel), horizontal and vertical pixel sizes of 1.54 μm. Using the orthophotos, four orthomosaics were generated in the Pix4D mapper software. The first orthomosaic was generated without using the control points. The other three mosaics were generated using 4, 8, and 16 premarked ground control points. To check the precision and accuracy of the orthomosaics, 46 premarked targets were uniformly distributed in the block. The three-dimensional (3-D) coordinates of the premarked targets were read on the orthomosaic and compared with the coordinates obtained by the geodetic survey real-time kinematic positioning method using the global navigation satellite system receiver signals. The cartographic accuracy standard was evaluated by discrepancies between these coordinates. The bias was analyzed by the Student's t test and the accuracy by the chi-square probability considering the orthomosaic on a scale of 1 ∶ 250, in which 90% of the points tested must have a planimetric error of control points the scale was 10-fold smaller (1 ∶ 3000).

  7. High-accuracy resolver-to-digital conversion via phase locked loop based on PID controller

    Science.gov (United States)

    Li, Yaoling; Wu, Zhong

    2018-03-01

    The problem of resolver-to-digital conversion (RDC) is transformed into the problem of angle tracking control, and a phase locked loop (PLL) method based on PID controller is proposed in this paper. This controller comprises a typical PI controller plus an incomplete differential which can avoid the amplification of higher-frequency noise components by filtering the phase detection error with a low-pass filter. Compared with conventional ones, the proposed PLL method makes the converter a system of type III and thus the conversion accuracy can be improved. Experimental results demonstrate the effectiveness of the proposed method.

  8. KLEIN: Coulomb functions for real lambda and positive energy to high accuracy

    International Nuclear Information System (INIS)

    Barnett, A.R.

    1981-01-01

    KLEIN computes relativistic Schroedinger (Klein-Gordon) equation solutions, i.e. Coulomb functions for real lambda > - 1, Fsub(lambda)(eta,x), Gsub(lambda)(eta,x), F'sub(lambda)(eta,x) and G'sub(lambda)(eta,x) for real kappa > 0 and real eta, - 10 4 4 . Hence it is also suitable for Bessel and spherical Bessel functions. Accuracies are in the range 10 -14 -10 -16 in oscillating region, and approx. equal to 10 -30 on an extended precision compiler. The program is suitable for generating Klein-Gordon wavefunctions for matching in pion and kaon physics. (orig.)

  9. High school science fair and research integrity

    Science.gov (United States)

    Dalley, Simon; Shepherd, Karen; Reisch, Joan

    2017-01-01

    Research misconduct has become an important matter of concern in the scientific community. The extent to which such behavior occurs early in science education has received little attention. In the current study, using the web-based data collection program REDCap, we obtained responses to an anonymous and voluntary survey about science fair from 65 high school students who recently competed in the Dallas Regional Science and Engineering Fair and from 237 STEM-track, post-high school students (undergraduates, 1st year medical students, and 1st year biomedical graduate students) doing research at UT Southwestern Medical Center. Of the post-high school students, 24% had competed in science fair during their high school education. Science fair experience was similar overall for the local cohort of Dallas regional students and the more diverse state/national cohort of post-high school students. Only one student out of 122 reported research misconduct, in his case making up the data. Unexpectedly, post-high school students who did not participate in science fair anticipated that carrying out science fair would be much more difficult than actually was the case, and 22% of the post-high school students anticipated that science fair participants would resort to research misconduct to overcome obstacles. No gender-based differences between students’ science fair experiences or expectations were evident. PMID:28328976

  10. Improvement in reliability and accuracy of heater tube eddy current testing by integration with an appropriate destructive test

    International Nuclear Information System (INIS)

    Giovanelli, F.; Gabiccini, S.; Tarli, R.; Motta, P.

    1988-01-01

    A specially developed destructive test is described showing how the reliability and accuracy of a non-destructive technique can be improved if it is suitably accompanied by an appropriate destructive test. The experiment was carried out on samples of AISI 304L tubes from the low-pressure (LP) preheaters of a BWR 900 MW nuclear plant. (author)

  11. Cause and Cure - Deterioration in Accuracy of CFD Simulations With Use of High-Aspect-Ratio Triangular Tetrahedral Grids

    Science.gov (United States)

    Chang, Sin-Chung; Chang, Chau-Lyan; Venkatachari, Balaji Shankar

    2017-01-01

    Traditionally high-aspect ratio triangular/tetrahedral meshes are avoided by CFD re-searchers in the vicinity of a solid wall, as it is known to reduce the accuracy of gradient computations in those regions and also cause numerical instability. Although for certain complex geometries, the use of high-aspect ratio triangular/tetrahedral elements in the vicinity of a solid wall can be replaced by quadrilateral/prismatic elements, ability to use triangular/tetrahedral elements in such regions without any degradation in accuracy can be beneficial from a mesh generation point of view. The benefits also carry over to numerical frameworks such as the space-time conservation element and solution element (CESE), where triangular/tetrahedral elements are the mandatory building blocks. With the requirement of the CESE method in mind, a rigorous mathematical framework that clearly identities the reason behind the difficulties in use of such high-aspect ratio triangular/tetrahedral elements is presented here. As will be shown, it turns out that the degree of accuracy deterioration of gradient computation involving a triangular element is hinged on the value of its shape factor Gamma def = sq sin Alpha1 + sq sin Alpha2 + sq sin Alpha3, where Alpha1; Alpha2 and Alpha3 are the internal angles of the element. In fact, it is shown that the degree of accuracy deterioration increases monotonically as the value of Gamma decreases monotonically from its maximal value 9/4 (attained by an equilateral triangle only) to a value much less than 1 (associated with a highly obtuse triangle). By taking advantage of the fact that a high-aspect ratio triangle is not necessarily highly obtuse, and in fact it can have a shape factor whose value is close to the maximal value 9/4, a potential solution to avoid accuracy deterioration of gradient computation associated with a high-aspect ratio triangular grid is given. Also a brief discussion on the extension of the current mathematical framework to the

  12. Affine-Invariant Geometric Constraints-Based High Accuracy Simultaneous Localization and Mapping

    Directory of Open Access Journals (Sweden)

    Gangchen Hua

    2017-01-01

    Full Text Available In this study we describe a new appearance-based loop-closure detection method for online incremental simultaneous localization and mapping (SLAM using affine-invariant-based geometric constraints. Unlike other pure bag-of-words-based approaches, our proposed method uses geometric constraints as a supplement to improve accuracy. By establishing an affine-invariant hypothesis, the proposed method excludes incorrect visual words and calculates the dispersion of correctly matched visual words to improve the accuracy of the likelihood calculation. In addition, camera’s intrinsic parameters and distortion coefficients are adequate for this method. 3D measuring is not necessary. We use the mechanism of Long-Term Memory and Working Memory (WM to manage the memory. Only a limited size of the WM is used for loop-closure detection; therefore the proposed method is suitable for large-scale real-time SLAM. We tested our method using the CityCenter and Lip6Indoor datasets. Our proposed method results can effectively correct the typical false-positive localization of previous methods, thus gaining better recall ratios and better precision.

  13. The use of high accuracy NAA for the certification of NIST Standard Reference Materials

    International Nuclear Information System (INIS)

    Becker, D.A.; Greenberg, R.R.; Stone, S.

    1991-01-01

    Neutron activation analysis (NAA) is only one of many analytical techniques used at the National Institute of Standards and Technology (NIST) for the certification of NIST Standard Reference Materials (SRMs). We compete daily against all of the other available analytical techniques in terms of accuracy, precision, and the cost required to obtain that requisite accuracy and precision. Over the years, the authors have found that NAA can and does compete favorably with these other techniques because of its' unique capabilities for redundancy and quality assurance. Good examples are the two new NIST leaf SRMs, Apple Leaves (SRM 1515) and Peach Leaves (SRM 1547). INAA was used to measure the homogeneity of 12 elements in 15 samples of each material at the 100 mg sample size. In addition, instrumental and radiochemical NAA combined for 27 elemental determinations, out of a total of 54 elemental determinations made on each material with all NIST techniques combined. This paper describes the NIST NAA procedures used in these analyses, the quality assurance techniques employed, and the analytical results for the 24 elements determined by NAA in these new botanical SRMs. The NAA results are also compared to the final certified values for these SRMs

  14. High-accuracy 3-D modeling of cultural heritage: the digitizing of Donatello's "Maddalena".

    Science.gov (United States)

    Guidi, Gabriele; Beraldin, J Angelo; Atzeni, Carlo

    2004-03-01

    Three-dimensional digital modeling of Heritage works of art through optical scanners, has been demonstrated in recent years with results of exceptional interest. However, the routine application of three-dimensional (3-D) modeling to Heritage conservation still requires the systematic investigation of a number of technical problems. In this paper, the acquisition process of the 3-D digital model of the Maddalena by Donatello, a wooden statue representing one of the major masterpieces of the Italian Renaissance which was swept away by the Florence flood of 1966 and successively restored, is described. The paper reports all the steps of the acquisition procedure, from the project planning to the solution of the various problems due to range camera calibration and to material non optically cooperative. Since the scientific focus is centered on the 3-D model overall dimensional accuracy, a methodology for its quality control is described. Such control has demonstrated how, in some situations, the ICP-based alignment can lead to incorrect results. To circumvent this difficulty we propose an alignment technique based on the fusion of ICP with close-range digital photogrammetry and a non-invasive procedure in order to generate a final accurate model. In the end detailed results are presented, demonstrating the improvement of the final model, and how the proposed sensor fusion ensure a pre-specified level of accuracy.

  15. Vision-based algorithms for high-accuracy measurements in an industrial bakery

    Science.gov (United States)

    Heleno, Paulo; Davies, Roger; Correia, Bento A. B.; Dinis, Joao

    2002-02-01

    This paper describes the machine vision algorithms developed for VIP3D, a measuring system used in an industrial bakery to monitor the dimensions and weight of loaves of bread (baguettes). The length and perimeter of more than 70 different varieties of baguette are measured with 1-mm accuracy, quickly, reliably and automatically. VIP3D uses a laser triangulation technique to measure the perimeter. The shape of the loaves is approximately cylindrical and the perimeter is defined as the convex hull of a cross-section perpendicular to the baguette axis at mid-length. A camera, mounted obliquely to the measuring plane, captures an image of a laser line projected onto the upper surface of the baguette. Three cameras are used to measure the baguette length, a solution adopted in order to minimize perspective-induced measurement errors. The paper describes in detail the machine vision algorithms developed to perform segmentation of the laser line and subsequent calculation of the perimeter of the baguette. The algorithms used to segment and measure the position of the ends of the baguette, to sub-pixel accuracy, are also described, as are the algorithms used to calibrate the measuring system and compensate for camera-induced image distortion.

  16. 12 CFR Appendix E to Part 334 - Interagency Guidelines Concerning the Accuracy and Integrity of Information Furnished to Consumer...

    Science.gov (United States)

    2010-01-01

    ... the consumer reporting agency properly to identify the consumer. (l) Conducting a periodic evaluation... and Integrity of Information Furnished to Consumer Reporting Agencies E Appendix E to Part 334 Banks... and Integrity of Information Furnished to Consumer Reporting Agencies The FDIC encourages voluntary...

  17. 12 CFR Appendix E to Part 717 - Interagency Guidelines Concerning the Accuracy and Integrity of Information Furnished to Consumer...

    Science.gov (United States)

    2010-01-01

    ... the consumer reporting agency properly to identify the consumer. (l) Conducting a periodic evaluation... and Integrity of Information Furnished to Consumer Reporting Agencies E Appendix E to Part 717 Banks... Integrity of Information Furnished to Consumer Reporting Agencies The NCUA encourages voluntary furnishing...

  18. Interobserver Variability and Accuracy of High-Definition Endoscopic Diagnosis for Gastric Intestinal Metaplasia among Experienced and Inexperienced Endoscopists

    Science.gov (United States)

    Hyun, Yil Sik; Bae, Joong Ho; Park, Hye Sun; Eun, Chang Soo

    2013-01-01

    Accurate diagnosis of gastric intestinal metaplasia is important; however, conventional endoscopy is known to be an unreliable modality for diagnosing gastric intestinal metaplasia (IM). The aims of the study were to evaluate the interobserver variation in diagnosing IM by high-definition (HD) endoscopy and the diagnostic accuracy of this modality for IM among experienced and inexperienced endoscopists. Selected 50 cases, taken with HD endoscopy, were sent for a diagnostic inquiry of gastric IM through visual inspection to five experienced and five inexperienced endoscopists. The interobserver agreement between endoscopists was evaluated to verify the diagnostic reliability of HD endoscopy in diagnosing IM, and the diagnostic accuracy, sensitivity, and specificity were evaluated for validity of HD endoscopy in diagnosing IM. Interobserver agreement among the experienced endoscopists was "poor" (κ = 0.38) and it was also "poor" (κ = 0.33) among the inexperienced endoscopists. The diagnostic accuracy of the experienced endoscopists was superior to that of the inexperienced endoscopists (P = 0.003). Since diagnosis through visual inspection is unreliable in the diagnosis of IM, all suspicious areas for gastric IM should be considered to be biopsied. Furthermore, endoscopic experience and education are needed to raise the diagnostic accuracy of gastric IM. PMID:23678267

  19. Interobserver variability and accuracy of high-definition endoscopic diagnosis for gastric intestinal metaplasia among experienced and inexperienced endoscopists.

    Science.gov (United States)

    Hyun, Yil Sik; Han, Dong Soo; Bae, Joong Ho; Park, Hye Sun; Eun, Chang Soo

    2013-05-01

    Accurate diagnosis of gastric intestinal metaplasia is important; however, conventional endoscopy is known to be an unreliable modality for diagnosing gastric intestinal metaplasia (IM). The aims of the study were to evaluate the interobserver variation in diagnosing IM by high-definition (HD) endoscopy and the diagnostic accuracy of this modality for IM among experienced and inexperienced endoscopists. Selected 50 cases, taken with HD endoscopy, were sent for a diagnostic inquiry of gastric IM through visual inspection to five experienced and five inexperienced endoscopists. The interobserver agreement between endoscopists was evaluated to verify the diagnostic reliability of HD endoscopy in diagnosing IM, and the diagnostic accuracy, sensitivity, and specificity were evaluated for validity of HD endoscopy in diagnosing IM. Interobserver agreement among the experienced endoscopists was "poor" (κ = 0.38) and it was also "poor" (κ = 0.33) among the inexperienced endoscopists. The diagnostic accuracy of the experienced endoscopists was superior to that of the inexperienced endoscopists (P = 0.003). Since diagnosis through visual inspection is unreliable in the diagnosis of IM, all suspicious areas for gastric IM should be considered to be biopsied. Furthermore, endoscopic experience and education are needed to raise the diagnostic accuracy of gastric IM.

  20. Energy Systems High-Pressure Test Laboratory | Energy Systems Integration

    Science.gov (United States)

    Facility | NREL Energy Systems High-Pressure Test Laboratory Energy Systems High-Pressure Test Laboratory In the Energy Systems Integration Facility's High-Pressure Test Laboratory, researchers can safely test high-pressure hydrogen components. Photo of researchers running an experiment with a hydrogen fuel

  1. Hyperbolic Method for Dispersive PDEs: Same High-Order of Accuracy for Solution, Gradient, and Hessian

    Science.gov (United States)

    Mazaheri, Alireza; Ricchiuto, Mario; Nishikawa, Hiroaki

    2016-01-01

    In this paper, we introduce a new hyperbolic first-order system for general dispersive partial differential equations (PDEs). We then extend the proposed system to general advection-diffusion-dispersion PDEs. We apply the fourth-order RD scheme of Ref. 1 to the proposed hyperbolic system, and solve time-dependent dispersive equations, including the classical two-soliton KdV and a dispersive shock case. We demonstrate that the predicted results, including the gradient and Hessian (second derivative), are in a very good agreement with the exact solutions. We then show that the RD scheme applied to the proposed system accurately captures dispersive shocks without numerical oscillations. We also verify that the solution, gradient and Hessian are predicted with equal order of accuracy.

  2. High-accuracy energy formulas for the attractive two-site Bose-Hubbard model

    Science.gov (United States)

    Ermakov, Igor; Byrnes, Tim; Bogoliubov, Nikolay

    2018-02-01

    The attractive two-site Bose-Hubbard model is studied within the framework of the analytical solution obtained by the application of the quantum inverse scattering method. The structure of the ground and excited states is analyzed in terms of solutions of Bethe equations, and an approximate solution for the Bethe roots is given. This yields approximate formulas for the ground-state energy and for the first excited-state energy. The obtained formulas work with remarkable precision for a wide range of parameters of the model, and are confirmed numerically. An expansion of the Bethe state vectors into a Fock space is also provided for evaluation of expectation values, although this does not have accuracy similar to that of the energies.

  3. Accuracy and repeatability positioning of high-performancel athe for non-circular turning

    Directory of Open Access Journals (Sweden)

    Majda Paweł

    2017-11-01

    Full Text Available This paper presents research on the accuracy and repeatability of CNC axis positioning in an innovative lathe with an additional Xs axis. This axis is used to perform movements synchronized with the angular position of the main drive, i.e. the spindle, and with the axial feed along the Z axis. This enables the one-pass turning of non-circular surfaces, rope and trapezoidal threads, as well as the surfaces of rotary tools such as a gear cutting hob, etc. The paper presents and discusses the interpretation of results and the calibration effects of positioning errors in the lathe’s numerical control system. Finally, it shows the geometric characteristics of the rope thread turned at various spindle speeds, including before and after-correction of the positioning error of the Xs axis.

  4. Accuracy and repeatability positioning of high-performancel athe for non-circular turning

    Science.gov (United States)

    Majda, Paweł; Powałka, Bartosz

    2017-11-01

    This paper presents research on the accuracy and repeatability of CNC axis positioning in an innovative lathe with an additional Xs axis. This axis is used to perform movements synchronized with the angular position of the main drive, i.e. the spindle, and with the axial feed along the Z axis. This enables the one-pass turning of non-circular surfaces, rope and trapezoidal threads, as well as the surfaces of rotary tools such as a gear cutting hob, etc. The paper presents and discusses the interpretation of results and the calibration effects of positioning errors in the lathe's numerical control system. Finally, it shows the geometric characteristics of the rope thread turned at various spindle speeds, including before and after-correction of the positioning error of the Xs axis.

  5. A method of high accuracy clock synchronization by frequency following with VCXO

    International Nuclear Information System (INIS)

    Ma Yichao; Wu Jie; Zhang Jie; Song Hongzhi; Kong Yang

    2011-01-01

    In this paper, the principle of the synchronous protocol of the IEEE1588 is analyzed, and the factors that affect the accuracy of synchronization is summarized. Through the hardware timer in a microcontroller, we give the exactly the time when a package is sent or received. So synchronization of the distributed clocks can reach 1 μs in this way. Another method to improve precision of the synchronization is to replace the traditional fixed frequency crystal of the slave device, which needs to follow up the master clock, by an adjustable VCXO. So it is possible to fine tune the frequency of the distributed clocks, and reduce the drift of clock, which shows great benefit for the clock synchronization. A test measurement shows the synchronization of distribute clocks can be better than 10 ns using this method, which is more accurate than the method realized by software. (authors)

  6. Development of economically viable, highly integrated, highly modular SEGIS architecture.

    Energy Technology Data Exchange (ETDEWEB)

    Enslin, Johan (Petra Solar, Inc., South Plainfield, NJ); Hamaoui, Ronald (Petra Solar, Inc., South Plainfield, NJ); Gonzalez, Sigifredo; Haddad, Ghaith (Petra Solar, Inc., South Plainfield, NJ); Rustom, Khalid (Petra Solar, Inc., South Plainfield, NJ); Stuby, Rick (Petra Solar, Inc., South Plainfield, NJ); Kuran, Mohammad (Petra Solar, Inc., South Plainfield, NJ); Mark, Evlyn (Petra Solar, Inc., South Plainfield, NJ); Amarin, Ruba (Petra Solar, Inc., South Plainfield, NJ); Alatrash, Hussam (Petra Solar, Inc., South Plainfield, NJ); Bower, Ward Isaac; Kuszmaul, Scott S.; Sena-Henderson, Lisa; David, Carolyn; Akhil, Abbas Ali

    2012-03-01

    Initiated in 2008, the SEGIS initiative is a partnership involving the U.S. DOE, Sandia National Laboratories, private sector companies, electric utilities, and universities. Projects supported under the initiative have focused on the complete-system development of solar technologies, with the dual goal of expanding renewable PV applications and addressing new challenges of connecting large-scale solar installations in higher penetrations to the electric grid. Petra Solar, Inc., a New Jersey-based company, received SEGIS funds to develop solutions to two of these key challenges: integrating increasing quantities of solar resources into the grid without compromising (and likely improving) power quality and reliability, and moving the design from a concept of intelligent system controls to successful commercialization. The resulting state-of-the art technology now includes a distributed photovoltaic (PV) architecture comprising AC modules that not only feed directly into the electrical grid at distribution levels but are equipped with new functions that improve voltage stability and thus enhance overall grid stability. This integrated PV system technology, known as SunWave, has applications for 'Power on a Pole,' and comes with a suite of technical capabilities, including advanced inverter and system controls, micro-inverters (capable of operating at both the 120V and 240V levels), communication system, network management system, and semiconductor integration. Collectively, these components are poised to reduce total system cost, increase the system's overall value and help mitigate the challenges of solar intermittency. Designed to be strategically located near point of load, the new SunWave technology is suitable for integration directly into the electrical grid but is also suitable for emerging microgrid applications. SunWave was showcased as part of a SEGIS Demonstration Conference at Pepco Holdings, Inc., on September 29, 2011, and is presently

  7. Audiovisual Integration in High Functioning Adults with Autism

    Science.gov (United States)

    Keane, Brian P.; Rosenthal, Orna; Chun, Nicole H.; Shams, Ladan

    2010-01-01

    Autism involves various perceptual benefits and deficits, but it is unclear if the disorder also involves anomalous audiovisual integration. To address this issue, we compared the performance of high-functioning adults with autism and matched controls on experiments investigating the audiovisual integration of speech, spatiotemporal relations, and…

  8. STTR Phase I: Low-Cost, High-Accuracy, Whole-Building Carbon Dioxide Monitoring for Demand Control Ventilation

    Energy Technology Data Exchange (ETDEWEB)

    Hallstrom, Jason; Ni, Zheng Richard

    2018-05-15

    This STTR Phase I project assessed the feasibility of a new CO2 sensing system optimized for low-cost, high-accuracy, whole-building monitoring for use in demand control ventilation. The focus was on the development of a wireless networking platform and associated firmware to provide signal conditioning and conversion, fault- and disruptiontolerant networking, and multi-hop routing at building scales to avoid wiring costs. Early exploration of a bridge (or “gateway”) to direct digital control services was also explored. Results of the project contributed to an improved understanding of a new electrochemical sensor for monitoring indoor CO2 concentrations, as well as the electronics and networking infrastructure required to deploy those sensors at building scales. New knowledge was acquired concerning the sensor’s accuracy, environmental response, and failure modes, and the acquisition electronics required to achieve accuracy over a wide range of CO2 concentrations. The project demonstrated that the new sensor offers repeatable correspondence with commercial optical sensors, with supporting electronics that offer gain accuracy within 0.5%, and acquisition accuracy within 1.5% across three orders of magnitude variation in generated current. Considering production, installation, and maintenance costs, the technology presents a foundation for achieving whole-building CO2 sensing at a price point below $0.066 / sq-ft – meeting economic feasibility criteria established by the Department of Energy. The technology developed under this award addresses obstacles on the critical path to enabling whole-building CO2 sensing and demand control ventilation in commercial retrofits, small commercial buildings, residential complexes, and other highpotential structures that have been slow to adopt these technologies. It presents an opportunity to significantly reduce energy use throughout the United States a

  9. Contribution of Regional White Matter Integrity to Visuospatial Construction Accuracy, Organizational Strategy, and Memory for a Complex Figure in Abstinent Alcoholics.

    Science.gov (United States)

    Rosenbloom, Margaret J; Sassoon, Stephanie A; Pfefferbaum, Adolf; Sullivan, Edith V

    2009-12-01

    Visuospatial construction ability as used in drawing complex figures is commonly impaired in chronic alcoholics, but memory for such information can be enhanced by use of a holistic drawing strategy during encoding. We administered the Rey-Osterrieth Complex Figure Test (ROCFT) to 41 alcoholic and 38 control men and women and assessed the contribution of diffusion tensor imaging (DTI) measures of integrity of selected white matter tracts to ROCFT copy accuracy, copy strategy, and recall accuracy. Although alcoholics copied the figure less accurately than controls, a more holistic strategy at copy was associated with better recall in both groups. Greater radial diffusivity, reflecting compromised myelin integrity, in occipital forceps and external capsule was associated with poorer copy accuracy in both groups. Lower FA, reflecting compromised fiber microstructure in the inferior cingulate bundle, which links frontal and medial temporal episodic memory systems, was associated with piecemeal copy strategy and poorer immediate recall in the alcoholics. The correlations were generally modest and should be considered exploratory. To the extent that the inferior cingulate was relatively spared in alcoholics, it may have provided an alternative pathway to the compromised frontal system for successful copy strategy and, by extension, aided recall.

  10. The Effect of Ionospheric Variability on the Accuracy of High Frequency Position Location

    Science.gov (United States)

    1981-08-01

    these problems are not the major ones in radio source location 1H. Rishbeth and 0. K. Garriot, 1969, Introduction to Ionospheric Physics, Academic Press ...ionospheric distur- banca ; and (4) employ an integrated network of ionosondes. The firt option recognizes the basic constraints of the available ionospheric...Rishbeth, H., and 0. K. Garriot, 1969, Introduction to Ionospheric Physics, Academic Press , NY. 2. Georges, T. M., 1967, Ionospheric Effects of

  11. High-accuracy CFD prediction methods for fluid and structure temperature fluctuations at T-junction for thermal fatigue evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Qian, Shaoxiang, E-mail: qian.shaoxiang@jgc.com [EN Technology Center, Process Technology Division, JGC Corporation, 2-3-1 Minato Mirai, Nishi-ku, Yokohama 220-6001 (Japan); Kanamaru, Shinichiro [EN Technology Center, Process Technology Division, JGC Corporation, 2-3-1 Minato Mirai, Nishi-ku, Yokohama 220-6001 (Japan); Kasahara, Naoto [Nuclear Engineering and Management, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan)

    2015-07-15

    Highlights: • Numerical methods for accurate prediction of thermal loading were proposed. • Predicted fluid temperature fluctuation (FTF) intensity is close to the experiment. • Predicted structure temperature fluctuation (STF) range is close to the experiment. • Predicted peak frequencies of FTF and STF also agree well with the experiment. • CFD results show the proposed numerical methods are of sufficiently high accuracy. - Abstract: Temperature fluctuations generated by the mixing of hot and cold fluids at a T-junction, which is widely used in nuclear power and process plants, can cause thermal fatigue failure. The conventional methods for evaluating thermal fatigue tend to provide insufficient accuracy, because they were developed based on limited experimental data and a simplified one-dimensional finite element analysis (FEA). CFD/FEA coupling analysis is expected as a useful tool for the more accurate evaluation of thermal fatigue. The present paper aims to verify the accuracy of proposed numerical methods of simulating fluid and structure temperature fluctuations at a T-junction for thermal fatigue evaluation. The dynamic Smagorinsky model (DSM) is used for large eddy simulation (LES) sub-grid scale (SGS) turbulence model, and a hybrid scheme (HS) is adopted for the calculation of convective terms in the governing equations. Also, heat transfer between fluid and structure is calculated directly through thermal conduction by creating a mesh with near wall resolution (NWR) by allocating grid points within the thermal boundary sub-layer. The simulation results show that the distribution of fluid temperature fluctuation intensity and the range of structure temperature fluctuation are remarkably close to the experimental results. Moreover, the peak frequencies of power spectrum density (PSD) of both fluid and structure temperature fluctuations also agree well with the experimental results. Therefore, the numerical methods used in the present paper are

  12. Radiometric inter-sensor cross-calibration uncertainty using a traceable high accuracy reference hyperspectral imager

    Science.gov (United States)

    Gorroño, Javier; Banks, Andrew C.; Fox, Nigel P.; Underwood, Craig

    2017-08-01

    Optical earth observation (EO) satellite sensors generally suffer from drifts and biases relative to their pre-launch calibration, caused by launch and/or time in the space environment. This places a severe limitation on the fundamental reliability and accuracy that can be assigned to satellite derived information, and is particularly critical for long time base studies for climate change and enabling interoperability and Analysis Ready Data. The proposed TRUTHS (Traceable Radiometry Underpinning Terrestrial and Helio-Studies) mission is explicitly designed to address this issue through re-calibrating itself directly to a primary standard of the international system of units (SI) in-orbit and then through the extension of this SI-traceability to other sensors through in-flight cross-calibration using a selection of Committee on Earth Observation Satellites (CEOS) recommended test sites. Where the characteristics of the sensor under test allows, this will result in a significant improvement in accuracy. This paper describes a set of tools, algorithms and methodologies that have been developed and used in order to estimate the radiometric uncertainty achievable for an indicative target sensor through in-flight cross-calibration using a well-calibrated hyperspectral SI-traceable reference sensor with observational characteristics such as TRUTHS. In this study, Multi-Spectral Imager (MSI) of Sentinel-2 and Landsat-8 Operational Land Imager (OLI) is evaluated as an example, however the analysis is readily translatable to larger-footprint sensors such as Sentinel-3 Ocean and Land Colour Instrument (OLCI) and Visible Infrared Imaging Radiometer Suite (VIIRS). This study considers the criticality of the instrumental and observational characteristics on pixel level reflectance factors, within a defined spatial region of interest (ROI) within the target site. It quantifies the main uncertainty contributors in the spectral, spatial, and temporal domains. The resultant tool

  13. High Efficiency Lighting with Integrated Adaptive Control (HELIAC), Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — The proposed project is the continued development of the High Efficiency Lighting with Integrated Adaptive Control (HELIAC) system. Solar radiation is not a viable...

  14. High Efficiency Lighting with Integrated Adaptive Control (HELIAC), Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — The innovation of the proposed project is the development of High Efficiency Lighting with Integrated Adaptive Control (HELIAC) systems to drive plant growth. Solar...

  15. High resolution time integration for Sn radiation transport

    International Nuclear Information System (INIS)

    Thoreson, Greg; McClarren, Ryan G.; Chang, Jae H.

    2008-01-01

    First order, second order and high resolution time discretization schemes are implemented and studied for the S n equations. The high resolution method employs a rate of convergence better than first order, but also suppresses artificial oscillations introduced by second order schemes in hyperbolic differential equations. All three methods were compared for accuracy and convergence rates. For non-absorbing problems, both second order and high resolution converged to the same solution as the first order with better convergence rates. High resolution is more accurate than first order and matches or exceeds the second order method. (authors)

  16. The high accuracy data processing system of laser interferometry signals based on MSP430

    Science.gov (United States)

    Qi, Yong-yue; Lin, Yu-chi; Zhao, Mei-rong

    2009-07-01

    Generally speaking there are two orthogonal signals used in single-frequency laser interferometer for differentiating direction and electronic subdivision. However there usually exist three errors with the interferential signals: zero offsets error, unequal amplitude error and quadrature phase shift error. These three errors have a serious impact on subdivision precision. Based on Heydemann error compensation algorithm, it is proposed to achieve compensation of the three errors. Due to complicated operation of the Heydemann mode, a improved arithmetic is advanced to decrease the calculating time effectively in accordance with the special characteristic that only one item of data will be changed in each fitting algorithm operation. Then a real-time and dynamic compensatory circuit is designed. Taking microchip MSP430 as the core of hardware system, two input signals with the three errors are turned into digital quantity by the AD7862. After data processing in line with improved arithmetic, two ideal signals without errors are output by the AD7225. At the same time two original signals are turned into relevant square wave and imported to the differentiating direction circuit. The impulse exported from the distinguishing direction circuit is counted by the timer of the microchip. According to the number of the pulse and the soft subdivision the final result is showed by LED. The arithmetic and the circuit are adopted to test the capability of a laser interferometer with 8 times optical path difference and the measuring accuracy of 12-14nm is achieved.

  17. A new phase-shift microscope designed for high accuracy stitching interferometry

    International Nuclear Information System (INIS)

    Thomasset, Muriel; Idir, Mourad; Polack, François; Bray, Michael; Servant, Jean-Jacques

    2013-01-01

    Characterizing nanofocusing X-ray mirrors for the soon coming nano-imaging beamlines of synchrotron light sources motivates the development of new instruments with improved performances. The sensitivity and accuracy goal is now fixed well under the nm level and, at the same time, the spatial frequency range of the measurement should be pushed toward 50 mm −1 . SOLEIL synchrotron facility has therefore undertaken to equip with an interferential microscope suitable for stitching interferometry at this performance level. In order to keep control on the whole metrology chain it was decided to build a custom instrument in partnership with two small optics companies EOTECH and MBO. The new instrument is a Michelson micro-interferometer equipped with a custom-designed telecentric objective. It achieves the large depth of focus suitable for performing reliable calibrations and measurements. The concept has been validated with a predevelopment set-up, delivered in July 2010, which showed a static repeatability below 1 nm PV despite a non-thermally stabilized environment. The final instrument was delivered early this year and was installed inside SOLEIL's controlled environment facility, where thorough characterization tests are under way. Latest test results and first stitching measurements are presented

  18. Experimental study of very low permeability rocks using a high accuracy permeameter

    International Nuclear Information System (INIS)

    Larive, Elodie

    2002-01-01

    The measurement of fluid flow through 'tight' rocks is important to provide a better understanding of physical processes involved in several industrial and natural problems. These include deep nuclear waste repositories, management of aquifers, gas, petroleum or geothermal reservoirs, or earthquakes prevention. The major part of this work consisted of the design, construction and use of an elaborate experimental apparatus allowing laboratory permeability measurements (fluid flow) of very low permeability rocks, on samples at a centimetric scale, to constrain their hydraulic behaviour at realistic in-situ conditions. The accuracy permeameter allows the use of several measurement methods, the steady-state flow method, the transient pulse method, and the sinusoidal pore pressure oscillation method. Measurements were made with the pore pressure oscillation method, using different waveform periods, at several pore and confining pressure conditions, on different materials. The permeability of one natural standard, Westerly granite, and an artificial one, a micro-porous cement, were measured, and results obtained agreed with previous measurements made on these materials showing the reliability of the permeameter. A study of a Yorkshire sandstone shows a relationship between rock microstructure, permeability anisotropy and thermal cracking. Microstructure, porosity and permeability concepts, and laboratory permeability measurements specifications are presented, the permeameter is described, and then permeability results obtained on the investigated materials are reported [fr

  19. A study for high accuracy measurement of residual stress by deep hole drilling technique

    Science.gov (United States)

    Kitano, Houichi; Okano, Shigetaka; Mochizuki, Masahito

    2012-08-01

    The deep hole drilling technique (DHD) received much attention in recent years as a method for measuring through-thickness residual stresses. However, some accuracy problems occur when residual stress evaluation is performed by the DHD technique. One of the reasons is that the traditional DHD evaluation formula applies to the plane stress condition. The second is that the effects of the plastic deformation produced in the drilling process and the deformation produced in the trepanning process are ignored. In this study, a modified evaluation formula, which is applied to the plane strain condition, is proposed. In addition, a new procedure is proposed which can consider the effects of the deformation produced in the DHD process by investigating the effects in detail by finite element (FE) analysis. Then, the evaluation results obtained by the new procedure are compared with that obtained by traditional DHD procedure by FE analysis. As a result, the new procedure evaluates the residual stress fields better than the traditional DHD procedure when the measuring object is thick enough that the stress condition can be assumed as the plane strain condition as in the model used in this study.

  20. On a novel low cost high accuracy experimental setup for tomographic particle image velocimetry

    International Nuclear Information System (INIS)

    Discetti, Stefano; Ianiro, Andrea; Astarita, Tommaso; Cardone, Gennaro

    2013-01-01

    This work deals with the critical aspects related to cost reduction of a Tomo PIV setup and to the bias errors introduced in the velocity measurements by the coherent motion of the ghost particles. The proposed solution consists of using two independent imaging systems composed of three (or more) low speed single frame cameras, which can be up to ten times cheaper than double shutter cameras with the same image quality. Each imaging system is used to reconstruct a particle distribution in the same measurement region, relative to the first and the second exposure, respectively. The reconstructed volumes are then interrogated by cross-correlation in order to obtain the measured velocity field, as in the standard tomographic PIV implementation. Moreover, differently from tomographic PIV, the ghost particle distributions of the two exposures are uncorrelated, since their spatial distribution is camera orientation dependent. For this reason, the proposed solution promises more accurate results, without the bias effect of the coherent ghost particles motion. Guidelines for the implementation and the application of the present method are proposed. The performances are assessed with a parametric study on synthetic experiments. The proposed low cost system produces a much lower modulation with respect to an equivalent three-camera system. Furthermore, the potential accuracy improvement using the Motion Tracking Enhanced MART (Novara et al 2010 Meas. Sci. Technol. 21 035401) is much higher than in the case of the standard implementation of tomographic PIV. (paper)

  1. Task force for integral test of High Energy nuclear data

    Energy Technology Data Exchange (ETDEWEB)

    Oyama, Yukio [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1998-11-01

    According to completion of the JENDL-High Energy file for neutron nuclear cross sections up to 50 MeV, a task force for integral test of high energy nuclear data was organized to discuss a guide line for integral test activities. A status of existing differential and integral experiments and how to perform such a test were discussed in the task force. Here the purpose and outline of the task force is explained with some future problems raised in discussion among the task member. (author)

  2. An investigation of airborne GPS/INS for high accuracy position and velocity determination

    Energy Technology Data Exchange (ETDEWEB)

    Sun, H.; Cannon, M.E. [Calgary Univ., AB (Canada). Dept. of Geomatics Engineering; Owen, T.E.; Meindl, M.A. [Sandia National Labs., Albuquerque, NM (United States)

    1993-12-31

    An airborne test using a differential GPS-INS system in a Twin Otter was conducted by Sandia National Laboratories to assess the feasibility of using the integrated system for cm-level position and cm/s velocity. The INS is a miniaturized ring-laser gyro IMU jointly developed by Sandia and Honeywell while the GPS system consists of the NovAtel GPSCard{trademark}. INS position, velocity and attitude data were computed using Sandia`s SANDAC flight computer system and logged at 4 Hz and GPS data was acquired at a 1 Hz rate. The mission was approximately 2.5 hours in duration and the aircraft reached separations of up to 19 km from the base station. The data was post-processed using a centralized Kalman filter approach in which the double differenced carrier phase measurements are used to update the INS data. The INS position is in turn used to detect and correct GPS carrier phase cycle slips and also to bridge GPS outages. Results are presented for the GPS-only case and also for integrated GPS/INS.

  3. High accuracy 235U(n,f) data in the resonance energy region

    International Nuclear Information System (INIS)

    Paradela, C.; Duran, I.; Alvarez-Pol, H.; Tassan-Got, L.; Audouin, L.; Berthier, B.; Isaev, S.; Le Naour, C.; Stephan, C.; David, S.; Ferrant, L.; Tarrio, D.; Abbondanno, U.; Tagliente, G.; Terlizzi, R.; Aerts, G.; Andriamonje, S.; Berthoumieux, E.; Dridi, W.; Gunsing, F.; Pancin, S.J.; Perrot, L.; Plukis, A.; Alvarez-Velarde, F.; Cano-Ott, D.; Gonzalez-Romero, E.; Martinez, T.; Villamarin, D.; Andrzejewski, J.; Marganiec, J.; Badurek, G.; Jericha, E.; Lederer, C.; Leeb, H.; Baumann, P.; Kerveno, M.; Lukic, S.; Rudolf, G.; Becvar, F.; Embid-Segura, M.; Krticka, M.; Vincente, M.C.; Calvino, F.; Cortes, G.; Poch, A.; Pretel, C.; Calviani, M.; Cennini, P.; Chiaveri, E.; Dahlfors, M.; Ferrari, A.; Kadi, Y.; Rubbia, C.; Sarchiapone, L.; Vlachoudis, V.; Weiss, C.; Capote, R.; Quesada, J.; Carrapico, C.; Goncalves, I.F.; Salgado, J.; Santos, C.; Tavora, L.; Vaz, P.; Chepel, V.; Ferreira-Marques, R.; Lindote, A.; Colonna, N.; Marrone, S.; Couture, A.; Cox, J.; Wiesher, M.; Dillmann, I.; Heil, M.; Kaeppeler, F.; Mosconi, M.; Plag, R.; Voss, F.; Walter, S.; Wisshak, K.; Domingo-Pardo, C.; Tain, J.L.; Eleftheriadis, C.; Lampoudis, C.; Savvidis, I.; Fujii, K.; Milazzo, P.M.; Moreau, C.; Furman, W.; Konovalov, V.; Goverdovski, A.; Ketlerov, V.; Gramegna, F.; Mastinu, P.; Praena, J.; Guerrero, C.; Haight, R.; Koehler, P.; Reifarth, R.; Igashira, M.; Karadimos, D.; Vlastou, R.; Massimi, C.; Pavlopoulos, P.; Mengoni, A.; Plompen, A.; Rullhusen, P.; Rauscher, T.; Ventura, A.; Pavlik, A.

    2016-01-01

    The 235 U neutron-induced cross section is widely used as reference cross section for measuring other fission cross sections, but in the resonance region it is not considered as an IAEA standard because of the scarce experimental data covering the full region. In this work, we deal with a new analysis of the experimental data obtained with a detection setup based on parallel plate ionization chambers (PPACs) at the CERN n-TOF facility in the range from 1 eV to 10 keV. The relative cross section has been normalised to the IAEA value in the region between 7.8 and 11 eV, which is claimed as well-known. Its comparison with the last IAEA reference files and with the present version of the ENDF evaluation leads to the following conclusions: 1) there is very good agreement with the shape of the ENDF cross-section in the resolved resonance range, while showing a lower background; 2) the ENDF integral values, apart from a 2% difference in the normalisation value at 7.8-11.0 eV, show a sharp drop at the transition from the resolved to the unresolved resonance energy regions; And 3) There is a very good agreement with the IAEA integral-data set, provided that an offset of 0.09 barn is applied in the whole energy range

  4. Performance enhancement of low-cost, high-accuracy, state estimation for vehicle collision prevention system using ANFIS

    Science.gov (United States)

    Saadeddin, Kamal; Abdel-Hafez, Mamoun F.; Jaradat, Mohammad A.; Jarrah, Mohammad Amin

    2013-12-01

    In this paper, a low-cost navigation system that fuses the measurements of the inertial navigation system (INS) and the global positioning system (GPS) receiver is developed. First, the system's dynamics are obtained based on a vehicle's kinematic model. Second, the INS and GPS measurements are fused using an extended Kalman filter (EKF) approach. Subsequently, an artificial intelligence based approach for the fusion of INS/GPS measurements is developed based on an Input-Delayed Adaptive Neuro-Fuzzy Inference System (IDANFIS). Experimental tests are conducted to demonstrate the performance of the two sensor fusion approaches. It is found that the use of the proposed IDANFIS approach achieves a reduction in the integration development time and an improvement in the estimation accuracy of the vehicle's position and velocity compared to the EKF based approach.

  5. ISPA - a high accuracy X-ray and gamma camera Exhibition LEPFest 2000

    CERN Multimedia

    2000-01-01

    ISPA offers ... Ten times better resolution than Anger cameras High efficiency single gamma counting Noise reduction by sensitivity to gamma energy ...for Single Photon Emission Computed Tomography (SPECT)

  6. Gated viewing and high-accuracy three-dimensional laser radar

    DEFF Research Database (Denmark)

    Busck, Jens; Heiselberg, Henning

    2004-01-01

    , a high PRF of 32 kHz, and a high-speed camera with gate times down to 200 ps and delay steps down to 100 ps. The electronics and the software also allow for gated viewing with automatic gain control versus range, whereby foreground backscatter can be suppressed. We describe our technique for the rapid...

  7. 12 CFR Appendix E to Part 41 - Interagency Guidelines Concerning the Accuracy and Integrity of Information Furnished to Consumer...

    Science.gov (United States)

    2010-01-01

    ... identify the consumer. (l) Conducting a periodic evaluation of its own practices, consumer reporting agency... and Integrity of Information Furnished to Consumer Reporting Agencies E Appendix E to Part 41 Banks... Furnished to Consumer Reporting Agencies Effective Date Note: At 74 FR 31512, July 1, 2009, appendix E was...

  8. 12 CFR Appendix E to Part 571 - Interagency Guidelines Concerning the Accuracy and Integrity of Information Furnished to Consumer...

    Science.gov (United States)

    2010-01-01

    ... the consumer reporting agency properly to identify the consumer. (l) Conducting a periodic evaluation... and Integrity of Information Furnished to Consumer Reporting Agencies E Appendix E to Part 571 Banks... Information Furnished to Consumer Reporting Agencies OTS encourages voluntary furnishing of information to...

  9. High-accuracy measurement of ship velocities by DGPS; DGPS ni yoru sensoku keisoku no koseidoka ni tsuite

    Energy Technology Data Exchange (ETDEWEB)

    Yamaguchi, S; Koterayama, W [Kyushu Univ., Fukuoka (Japan). Research Inst. for Applied Mechanics

    1996-04-10

    The differential global positioning system (DGPS) can eliminate most of errors in ship velocity measurement by GPS positioning alone. Through two rounds of marine observations by towing an observation robot in summer 1995, the authors attempted high-accuracy measurement of ship velocities by DGPS, and also carried out both positioning by GPS alone and measurement using the bottom track of ADCP (acoustic Doppler current profiler). In this paper, the results obtained by these measurement methods were examined through comparison among them, and the accuracy of the measured ship velocities was considered. In DGPS measurement, both translocation method and interference positioning method were used. ADCP mounted on the observation robot allowed measurement of the velocity of current meter itself by its bottom track in shallow sea areas less than 350m. As the result of these marine observations, it was confirmed that the accuracy equivalent to that of direct measurement by bottom track is possible to be obtained by DGPS. 3 refs., 5 figs., 1 tab.

  10. An Integrated GNSS/INS/LiDAR-SLAM Positioning Method for Highly Accurate Forest Stem Mapping

    Directory of Open Access Journals (Sweden)

    Chuang Qian

    2016-12-01

    Full Text Available Forest mapping, one of the main components of performing a forest inventory, is an important driving force in the development of laser scanning. Mobile laser scanning (MLS, in which laser scanners are installed on moving platforms, has been studied as a convenient measurement method for forest mapping in the past several years. Positioning and attitude accuracies are important for forest mapping using MLS systems. Inertial Navigation Systems (INSs and Global Navigation Satellite Systems (GNSSs are typical and popular positioning and attitude sensors used in MLS systems. In forest environments, because of the loss of signal due to occlusion and severe multipath effects, the positioning accuracy of GNSS is severely degraded, and even that of GNSS/INS decreases considerably. Light Detection and Ranging (LiDAR-based Simultaneous Localization and Mapping (SLAM can achieve higher positioning accuracy in environments containing many features and is commonly implemented in GNSS-denied indoor environments. Forests are different from an indoor environment in that the GNSS signal is available to some extent in a forest. Although the positioning accuracy of GNSS/INS is reduced, estimates of heading angle and velocity can maintain high accurate even with fewer satellites. GNSS/INS and the LiDAR-based SLAM technique can be effectively integrated to form a sustainable, highly accurate positioning and mapping solution for use in forests without additional hardware costs. In this study, information such as heading angles and velocities extracted from a GNSS/INS is utilized to improve the positioning accuracy of the SLAM solution, and two information-aided SLAM methods are proposed. First, a heading angle-aided SLAM (H-aided SLAM method is proposed that supplies the heading angle from GNSS/INS to SLAM. Field test results show that the horizontal positioning accuracy of an entire trajectory of 800 m is 0.13 m and is significantly improved (by 70% compared to that

  11. Neutrino mass from cosmology: impact of high-accuracy measurement of the Hubble constant

    Energy Technology Data Exchange (ETDEWEB)

    Sekiguchi, Toyokazu [Institute for Cosmic Ray Research, University of Tokyo, Kashiwa 277-8582 (Japan); Ichikawa, Kazuhide [Department of Micro Engineering, Kyoto University, Kyoto 606-8501 (Japan); Takahashi, Tomo [Department of Physics, Saga University, Saga 840-8502 (Japan); Greenhill, Lincoln, E-mail: sekiguti@icrr.u-tokyo.ac.jp, E-mail: kazuhide@me.kyoto-u.ac.jp, E-mail: tomot@cc.saga-u.ac.jp, E-mail: greenhill@cfa.harvard.edu [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States)

    2010-03-01

    Non-zero neutrino mass would affect the evolution of the Universe in observable ways, and a strong constraint on the mass can be achieved using combinations of cosmological data sets. We focus on the power spectrum of cosmic microwave background (CMB) anisotropies, the Hubble constant H{sub 0}, and the length scale for baryon acoustic oscillations (BAO) to investigate the constraint on the neutrino mass, m{sub ν}. We analyze data from multiple existing CMB studies (WMAP5, ACBAR, CBI, BOOMERANG, and QUAD), recent measurement of H{sub 0} (SHOES), with about two times lower uncertainty (5 %) than previous estimates, and recent treatments of BAO from the Sloan Digital Sky Survey (SDSS). We obtained an upper limit of m{sub ν} < 0.2eV (95 % C.L.), for a flat ΛCDM model. This is a 40 % reduction in the limit derived from previous H{sub 0} estimates and one-third lower than can be achieved with extant CMB and BAO data. We also analyze the impact of smaller uncertainty on measurements of H{sub 0} as may be anticipated in the near term, in combination with CMB data from the Planck mission, and BAO data from the SDSS/BOSS program. We demonstrate the possibility of a 5σ detection for a fiducial neutrino mass of 0.1 eV or a 95 % upper limit of 0.04 eV for a fiducial of m{sub ν} = 0 eV. These constraints are about 50 % better than those achieved without external constraint. We further investigate the impact on modeling where the dark-energy equation of state is constant but not necessarily -1, or where a non-flat universe is allowed. In these cases, the next-generation accuracies of Planck, BOSS, and 1 % measurement of H{sub 0} would all be required to obtain the limit m{sub ν} < 0.05−0.06 eV (95 % C.L.) for the fiducial of m{sub ν} = 0 eV. The independence of systematics argues for pursuit of both BAO and H{sub 0} measurements.

  12. Challenges in high accuracy surface replication for micro optics and micro fluidics manufacture

    DEFF Research Database (Denmark)

    Tosello, Guido; Hansen, Hans Nørgaard; Calaon, Matteo

    2014-01-01

    Patterning the surface of polymer components with microstructured geometries is employed in optical and microfluidic applications. Mass fabrication of polymer micro structured products is enabled by replication technologies such as injection moulding. Micro structured tools are also produced...... by replication technologies such as nickel electroplating. All replication steps are enabled by a high precision master and high reproduction fidelity to ensure that the functionalities associated with the design are transferred to the final component. Engineered surface micro structures can be either...

  13. Management systems for high reliability organizations. Integration and effectiveness; Managementsysteme fuer Hochzuverlaessigkeitsorganisationen. Integration und Wirksamkeit

    Energy Technology Data Exchange (ETDEWEB)

    Mayer, Michael

    2015-03-09

    The scope of the thesis is the development of a method for improvement of efficient integrated management systems for high reliability organizations (HRO). A comprehensive analysis of severe accident prevention is performed. Severe accident management, mitigation measures and business continuity management are not included. High reliability organizations are complex and potentially dynamic organization forms that can be inherently dangerous like nuclear power plants, offshore platforms, chemical facilities, large ships or large aircrafts. A recursive generic management system model (RGM) was development based on the following factors: systemic and cybernetic Asepcts; integration of different management fields, high decision quality, integration of efficient methods of safety and risk analysis, integration of human reliability aspects, effectiveness evaluation and improvement.

  14. A content analysis of the quantity and accuracy of dietary supplement information found in magazines with high adolescent readership.

    Science.gov (United States)

    Shaw, Patricia; Zhang, Vivien; Metallinos-Katsaras, Elizabeth

    2009-02-01

    The objective of this study was to examine the quantity and accuracy of dietary supplement (DS) information through magazines with high adolescent readership. Eight (8) magazines (3 teen and 5 adult with high teen readership) were selected. A content analysis for DS was conducted on advertisements and editorials (i.e., articles, advice columns, and bulletins). Noted claims/cautions regarding DS were evaluated for accuracy using Medlineplus.gov and Naturaldatabase.com. Claims for dietary supplements with three or more types of ingredients and those in advertisements were not evaluated. Advertisements were evaluated with respect to size, referenced research, testimonials, and Dietary Supplement Health and Education Act of 1994 (DSHEA) warning visibility. Eighty-eight (88) issues from eight magazines yielded 238 DS references. Fifty (50) issues from five magazines contained no DS reference. Among teen magazines, seven DS references were found: five in the editorials and two in advertisements. In adult magazines, 231 DS references were found: 139 in editorials and 92 in advertisements. Of the 88 claims evaluated, 15% were accurate, 23% were inconclusive, 3% were inaccurate, 5% were partially accurate, and 55% were unsubstantiated (i.e., not listed in reference databases). Of the 94 DS evaluated in advertisements, 43% were full page or more, 79% did not have a DSHEA warning visible, 46% referred to research, and 32% used testimonials. Teen magazines contain few references to DS, none accurate. Adult magazines that have a high teen readership contain a substantial amount of DS information with questionable accuracy, raising concerns that this information may increase the chances of inappropriate DS use by adolescents, thereby increasing the potential for unexpected effects or possible harm.

  15. Interethnic differences in the accuracy of anthropometric indicators of obesity in screening for high risk of coronary heart disease

    Science.gov (United States)

    Herrera, VM; Casas, JP; Miranda, JJ; Perel, P; Pichardo, R; González, A; Sanchez, JR; Ferreccio, C; Aguilera, X; Silva, E; Oróstegui, M; Gómez, LF; Chirinos, JA; Medina-Lezama, J; Pérez, CM; Suárez, E; Ortiz, AP; Rosero, L; Schapochnik, N; Ortiz, Z; Ferrante, D; Diaz, M; Bautista, LE

    2009-01-01

    Background Cut points for defining obesity have been derived from mortality data among Whites from Europe and the United States and their accuracy to screen for high risk of coronary heart disease (CHD) in other ethnic groups has been questioned. Objective To compare the accuracy and to define ethnic and gender-specific optimal cut points for body mass index (BMI), waist circumference (WC) and waist-to-hip ratio (WHR) when they are used in screening for high risk of CHD in the Latin-American and the US populations. Methods We estimated the accuracy and optimal cut points for BMI, WC and WHR to screen for CHD risk in Latin Americans (n=18 976), non-Hispanic Whites (Whites; n=8956), non-Hispanic Blacks (Blacks; n=5205) and Hispanics (n=5803). High risk of CHD was defined as a 10-year risk ≥20% (Framingham equation). The area under the receiver operator characteristic curve (AUC) and the misclassification-cost term were used to assess accuracy and to identify optimal cut points. Results WHR had the highest AUC in all ethnic groups (from 0.75 to 0.82) and BMI had the lowest (from 0.50 to 0.59). Optimal cut point for BMI was similar across ethnic/gender groups (27 kg/m2). In women, cut points for WC (94 cm) and WHR (0.91) were consistent by ethnicity. In men, cut points for WC and WHR varied significantly with ethnicity: from 91 cm in Latin Americans to 102 cm in Whites, and from 0.94 in Latin Americans to 0.99 in Hispanics, respectively. Conclusion WHR is the most accurate anthropometric indicator to screen for high risk of CHD, whereas BMI is almost uninformative. The same BMI cut point should be used in all men and women. Unique cut points for WC and WHR should be used in all women, but ethnic-specific cut points seem warranted among men. PMID:19238159

  16. High accuracy and precision micro injection moulding of thermoplastic elastomers micro ring production

    DEFF Research Database (Denmark)

    Calaon, Matteo; Tosello, Guido; Elsborg, René

    2016-01-01

    The mass-replication nature of the process calls for fast monitoring of process parameters and product geometrical characteristics. In this direction, the present study addresses the possibility to develop a micro manufacturing platform for micro assembly injection moulding with real-time process....../product monitoring and metrology. The study represent a new concept yet to be developed with great potential for high precision mass-manufacturing of highly functional 3D multi-material (i.e. including metal/soft polymer) micro components. The activities related to HINMICO project objectives proves the importance...

  17. The integration of familiarity and recollection information in short-term recognition: modeling speed-accuracy trade-off functions.

    Science.gov (United States)

    Göthe, Katrin; Oberauer, Klaus

    2008-05-01

    Dual process models postulate familiarity and recollection as the basis of the recognition process. We investigated the time-course of integration of the two information sources to one recognition judgment in a working memory task. We tested 24 subjects with a response signal variant of the modified Sternberg recognition task (Oberauer, 2001) to isolate the time course of three different probe types indicating different combinations of familiarity and source information. We compared two mathematical models implementing different ways of integrating familiarity and recollection. Within each model, we tested three assumptions about the nature of the familiarity signal, with familiarity having (a) only positive values, indicating similarity of the probe with the memory list, (b) only negative values, indicating novelty, or (c) both positive and negative values. Both models provided good fits to the data. A model combining the outputs of both processes additively (Integration Model) gave an overall better fit to the data than a model based on a continuous familiarity signal and a probabilistic all-or-none recollection process (Dominance Model).

  18. High resolution integral holography using Fourier ptychographic approach.

    Science.gov (United States)

    Li, Zhaohui; Zhang, Jianqi; Wang, Xiaorui; Liu, Delian

    2014-12-29

    An innovative approach is proposed for calculating high resolution computer generated integral holograms by using the Fourier Ptychographic (FP) algorithm. The approach initializes a high resolution complex hologram with a random guess, and then stitches together low resolution multi-view images, synthesized from the elemental images captured by integral imaging (II), to recover the high resolution hologram through an iterative retrieval with FP constrains. This paper begins with an analysis of the principle of hologram synthesis from multi-projections, followed by an accurate determination of the constrains required in the Fourier ptychographic integral-holography (FPIH). Next, the procedure of the approach is described in detail. Finally, optical reconstructions are performed and the results are demonstrated. Theoretical analysis and experiments show that our proposed approach can reconstruct 3D scenes with high resolution.

  19. High Accuracy Three-dimensional Simulation of Micro Injection Moulded Parts

    DEFF Research Database (Denmark)

    Tosello, Guido; Costa, F. S.; Hansen, Hans Nørgaard

    2011-01-01

    Micro injection moulding (μIM) is the key replication technology for high precision manufacturing of polymer micro products. Data analysis and simulations on micro-moulding experiments have been conducted during the present validation study. Detailed information about the μIM process was gathered...

  20. High resolution time integration for SN radiation transport

    International Nuclear Information System (INIS)

    Thoreson, Greg; McClarren, Ryan G.; Chang, Jae H.

    2009-01-01

    First-order, second-order, and high resolution time discretization schemes are implemented and studied for the discrete ordinates (S N ) equations. The high resolution method employs a rate of convergence better than first-order, but also suppresses artificial oscillations introduced by second-order schemes in hyperbolic partial differential equations. The high resolution method achieves these properties by nonlinearly adapting the time stencil to use a first-order method in regions where oscillations could be created. We employ a quasi-linear solution scheme to solve the nonlinear equations that arise from the high resolution method. All three methods were compared for accuracy and convergence rates. For non-absorbing problems, both second-order and high resolution converged to the same solution as the first-order with better convergence rates. High resolution is more accurate than first-order and matches or exceeds the second-order method

  1. Museum genomics: low-cost and high-accuracy genetic data from historical specimens.

    Science.gov (United States)

    Rowe, Kevin C; Singhal, Sonal; Macmanes, Matthew D; Ayroles, Julien F; Morelli, Toni Lyn; Rubidge, Emily M; Bi, Ke; Moritz, Craig C

    2011-11-01

    Natural history collections are unparalleled repositories of geographical and temporal variation in faunal conditions. Molecular studies offer an opportunity to uncover much of this variation; however, genetic studies of historical museum specimens typically rely on extracting highly degraded and chemically modified DNA samples from skins, skulls or other dried samples. Despite this limitation, obtaining short fragments of DNA sequences using traditional PCR amplification of DNA has been the primary method for genetic study of historical specimens. Few laboratories have succeeded in obtaining genome-scale sequences from historical specimens and then only with considerable effort and cost. Here, we describe a low-cost approach using high-throughput next-generation sequencing to obtain reliable genome-scale sequence data from a traditionally preserved mammal skin and skull using a simple extraction protocol. We show that single-nucleotide polymorphisms (SNPs) from the genome sequences obtained independently from the skin and from the skull are highly repeatable compared to a reference genome. © 2011 Blackwell Publishing Ltd.

  2. Algorithm of dynamic regulation of a system of duct, for a high accuracy climatic system

    Science.gov (United States)

    Arbatskiy, A. A.; Afonina, G. N.; Glazov, V. S.

    2017-11-01

    Currently, major part of climatic system, are stationary in projected mode only. At the same time, many modern industrial sites, require constant or periodical changes in technological process. That is 80% of the time, the industrial site is not require ventilation system in projected mode and high precision of climatic parameters must maintain. While that not constantly is in use for climatic systems, which use in parallel for different rooms, we will be have a problem for balance of duct system. For this problem, was created the algorithm for quantity regulation, with minimal changes. Dynamic duct system: Developed of parallel control system of air balance, with high precision of climatic parameters. The Algorithm provide a permanent pressure in main duct, in different a flow of air. Therefore, the ending devises air flow have only one parameter for regulation - flaps open area. Precision of regulation increase and the climatic system provide high precision for temperature and humidity (0,5C for temperature, 5% for relative humidity). Result: The research has been made in CFD-system - PHOENICS. Results for velocity of air in duct, for pressure of air in duct for different operation mode, has been obtained. Equation for air valves positions, with different parameters for climate in room’s, has been obtained. Energy saving potential for dynamic duct system, for different types of a rooms, has been calculated.

  3. High-accuracy alignment based on atmospherical dispersion - technological approaches and solutions for the dual-wavelength transmitter

    International Nuclear Information System (INIS)

    Burkhard, Boeckem

    1999-01-01

    In the course of the progressive developments of sophisticated geodetic systems utilizing electromagnetic waves in the visible or near IR-range a more detailed knowledge of the propagation medium and coevally solutions of atmospherically induced limitations will become important. An alignment system based on atmospherical dispersion, called a dispersometer, is a metrological solution to the atmospherically induced limitations, in optical alignment and direction observations of high accuracy. In the dispersometer we are using the dual-wavelength method for dispersive air to obtain refraction compensated angle measurements, the detrimental impact of atmospheric turbulence notwithstanding. The principle of the dual-wavelength method utilizes atmospherical dispersion, i.e. the wavelength dependence of the refractive index. The difference angle between two light beams of different wavelengths, which is called the dispersion angle Δβ, is to first approximation proportional to the refraction angle: β IR ν(β blue - β IR ) = ν Δβ, this equation implies that the dispersion angle has to be measured at least 42 times more accurate than the desired accuracy of the refraction angle for the wavelengths used in the present dispersometer. This required accuracy constitutes one major difficulty for the instrumental performance in applying the dispersion effect. However, the dual-wavelength method can only be successfully used in an optimized transmitter-receiver combination. Beyond the above mentioned resolution requirement for the detector, major difficulties in instrumental realization arise in the availability of a suitable dual-wavelength laser light source, laser light modulation with a very high extinction ratio and coaxial emittance of mono-mode radiation at both wavelengths. Therefore, this paper focuses on the solutions of the dual-wavelength transmitter introducing a new hardware approach and a complete re-design of the in [1] proposed conception of the dual

  4. A practical procedure to improve the accuracy of radiochromic film dosimetry. A integration with a correction method of uniformity correction and a red/blue correction method

    International Nuclear Information System (INIS)

    Uehara, Ryuzo; Tachibana, Hidenobu; Ito, Yasushi; Yoshino, Shinichi; Matsubayashi, Fumiyasu; Sato, Tomoharu

    2013-01-01

    It has been reported that the light scattering could worsen the accuracy of dose distribution measurement using a radiochromic film. The purpose of this study was to investigate the accuracy of two different films, EDR2 and EBT2, as film dosimetry tools. The effectiveness of a correction method for the non-uniformity caused from EBT2 film and the light scattering was also evaluated. In addition the efficacy of this correction method integrated with the red/blue correction method was assessed. EDR2 and EBT2 films were read using a flatbed charge-coupled device scanner (EPSON 10000 G). Dose differences on the axis perpendicular to the scanner lamp movement axis were within 1% with EDR2, but exceeded 3% (Maximum: +8%) with EBT2. The non-uniformity correction method, after a single film exposure, was applied to the readout of the films. A corrected dose distribution data was subsequently created. The correction method showed more than 10%-better pass ratios in dose difference evaluation than when the correction method was not applied. The red/blue correction method resulted in 5%-improvement compared with the standard procedure that employed red color only. The correction method with EBT2 proved to be able to rapidly correct non-uniformity, and has potential for routine clinical intensity modulated radiation therapy (IMRT) dose verification if the accuracy of EBT2 is required to be similar to that of EDR2. The use of red/blue correction method may improve the accuracy, but we recommend we should use the red/blue correction method carefully and understand the characteristics of EBT2 for red color only and the red/blue correction method. (author)

  5. [A practical procedure to improve the accuracy of radiochromic film dosimetry: a integration with a correction method of uniformity correction and a red/blue correction method].

    Science.gov (United States)

    Uehara, Ryuzo; Tachibana, Hidenobu; Ito, Yasushi; Yoshino, Shinichi; Matsubayashi, Fumiyasu; Sato, Tomoharu

    2013-06-01

    It has been reported that the light scattering could worsen the accuracy of dose distribution measurement using a radiochromic film. The purpose of this study was to investigate the accuracy of two different films, EDR2 and EBT2, as film dosimetry tools. The effectiveness of a correction method for the non-uniformity caused from EBT2 film and the light scattering was also evaluated. In addition the efficacy of this correction method integrated with the red/blue correction method was assessed. EDR2 and EBT2 films were read using a flatbed charge-coupled device scanner (EPSON 10000G). Dose differences on the axis perpendicular to the scanner lamp movement axis were within 1% with EDR2, but exceeded 3% (Maximum: +8%) with EBT2. The non-uniformity correction method, after a single film exposure, was applied to the readout of the films. A corrected dose distribution data was subsequently created. The correction method showed more than 10%-better pass ratios in dose difference evaluation than when the correction method was not applied. The red/blue correction method resulted in 5%-improvement compared with the standard procedure that employed red color only. The correction method with EBT2 proved to be able to rapidly correct non-uniformity, and has potential for routine clinical IMRT dose verification if the accuracy of EBT2 is required to be similar to that of EDR2. The use of red/blue correction method may improve the accuracy, but we recommend we should use the red/blue correction method carefully and understand the characteristics of EBT2 for red color only and the red/blue correction method.

  6. Suspended Integrated Strip-line Transition Design for Highly Integrated Radar Systems

    Science.gov (United States)

    2017-03-01

    technology. The measured results show good correlation to the simulated results with a return loss and insertion loss of less than 10 dB and greater...SSS); Suspended Integrated Strip-line (SISL) RF packaging; Ultra-wideband (UWB). Introduction The next generation of highly integrated radar...RF Circuit Design,” Second Edition, Pearson Education, 2009. 3. B. Ma, A. Chousseaud, and S. Toutain, “A new design of compact planar microstrip

  7. Modelling and Control of Stepper Motors for High Accuracy Positioning Systems Used in Radioactive Environments

    CERN Document Server

    Picatoste Ruilope, Ricardo; Masi, Alessandro

    Hybrid Stepper Motors are widely used in open-loop position applications. They are the choice of actuation for the collimators in the Large Hadron Collider, the largest particle accelerator at CERN. In this case the positioning requirements and the highly radioactive operating environment are unique. The latter forces both the use of long cables to connect the motors to the drives which act as transmission lines and also prevents the use of standard position sensors. However, reliable and precise operation of the collimators is critical for the machine, requiring the prevention of step loss in the motors and maintenance to be foreseen in case of mechanical degradation. In order to make the above possible, an approach is proposed for the application of an Extended Kalman Filter to a sensorless stepper motor drive, when the motor is separated from its drive by long cables. When the long cables and high frequency pulse width modulated control voltage signals are used together, the electrical signals difer greatl...

  8. The study of optimization on process parameters of high-accuracy computerized numerical control polishing

    Science.gov (United States)

    Huang, Wei-Ren; Huang, Shih-Pu; Tsai, Tsung-Yueh; Lin, Yi-Jyun; Yu, Zong-Ru; Kuo, Ching-Hsiang; Hsu, Wei-Yao; Young, Hong-Tsu

    2017-09-01

    Spherical lenses lead to forming spherical aberration and reduced optical performance. Consequently, in practice optical system shall apply a combination of spherical lenses for aberration correction. Thus, the volume of the optical system increased. In modern optical systems, aspherical lenses have been widely used because of their high optical performance with less optical components. However, aspherical surfaces cannot be fabricated by traditional full aperture polishing process due to their varying curvature. Sub-aperture computer numerical control (CNC) polishing is adopted for aspherical surface fabrication in recent years. By using CNC polishing process, mid-spatial frequency (MSF) error is normally accompanied during this process. And the MSF surface texture of optics decreases the optical performance for high precision optical system, especially for short-wavelength applications. Based on a bonnet polishing CNC machine, this study focuses on the relationship between MSF surface texture and CNC polishing parameters, which include feed rate, head speed, track spacing and path direction. The power spectral density (PSD) analysis is used to judge the MSF level caused by those polishing parameters. The test results show that controlling the removal depth of single polishing path, through the feed rate, and without same direction polishing path for higher total removal depth can efficiently reduce the MSF error. To verify the optical polishing parameters, we divided a correction polishing process to several polishing runs with different direction polishing paths. Compare to one shot polishing run, multi-direction path polishing plan could produce better surface quality on the optics.

  9. High accuracy injection circuit for the calibration of a large pixel sensor matrix

    International Nuclear Information System (INIS)

    Quartieri, E.; Comotti, D.; Manghisoni, M.

    2013-01-01

    Semiconductor pixel detectors, for particle tracking and vertexing in high energy physics experiments as well as for X-ray imaging, in particular for synchrotron light sources and XFELs, require a large area sensor matrix. This work will discuss the design and the characterization of a high-linearity, low dispersion injection circuit to be used for pixel-level calibration of detector readout electronics in a large pixel sensor matrix. The circuit provides a useful tool for the characterization of the readout electronics of the pixel cell unit for both monolithic active pixel sensors and hybrid pixel detectors. In the latter case, the circuit allows for precise analogue test of the readout channel already at the chip level, when no sensor is connected. Moreover, it provides a simple means for calibration of readout electronics once the detector has been connected to the chip. Two injection techniques can be provided by the circuit: one for a charge sensitive amplification and the other for a transresistance readout channel. The aim of the paper is to describe the architecture and the design guidelines of the calibration circuit, which has been implemented in a 130 nm CMOS technology. Moreover, experimental results of the proposed injection circuit will be presented in terms of linearity and dispersion

  10. Accuracy of an automated system for tuberculosis detection on chest radiographs in high-risk screening.

    Science.gov (United States)

    Melendez, J; Hogeweg, L; Sánchez, C I; Philipsen, R H H M; Aldridge, R W; Hayward, A C; Abubakar, I; van Ginneken, B; Story, A

    2018-05-01

    Tuberculosis (TB) screening programmes can be optimised by reducing the number of chest radiographs (CXRs) requiring interpretation by human experts. To evaluate the performance of computerised detection software in triaging CXRs in a high-throughput digital mobile TB screening programme. A retrospective evaluation of the software was performed on a database of 38 961 postero-anterior CXRs from unique individuals seen between 2005 and 2010, 87 of whom were diagnosed with TB. The software generated a TB likelihood score for each CXR. This score was compared with a reference standard for notified active pulmonary TB using receiver operating characteristic (ROC) curve and localisation ROC (LROC) curve analyses. On ROC curve analysis, software specificity was 55.71% (95%CI 55.21-56.20) and negative predictive value was 99.98% (95%CI 99.95-99.99), at a sensitivity of 95%. The area under the ROC curve was 0.90 (95%CI 0.86-0.93). Results of the LROC curve analysis were similar. The software could identify more than half of the normal images in a TB screening setting while maintaining high sensitivity, and may therefore be used for triage.

  11. A three axis turntable's online initial state measurement method based on the high-accuracy laser gyro SINS

    Science.gov (United States)

    Gao, Chunfeng; Wei, Guo; Wang, Qi; Xiong, Zhenyu; Wang, Qun; Long, Xingwu

    2016-10-01

    As an indispensable equipment in inertial technology tests, the three-axis turntable is widely used in the calibration of various types inertial navigation systems (INS). In order to ensure the calibration accuracy of INS, we need to accurately measure the initial state of the turntable. However, the traditional measuring method needs a lot of exterior equipment (such as level instrument, north seeker, autocollimator, etc.), and the test processing is complex, low efficiency. Therefore, it is relatively difficult for the inertial measurement equipment manufacturers to realize the self-inspection of the turntable. Owing to the high precision attitude information provided by the laser gyro strapdown inertial navigation system (SINS) after fine alignment, we can use it as the attitude reference of initial state measurement of three-axis turntable. For the principle that the fixed rotation vector increment is not affected by measuring point, we use the laser gyro INS and the encoder of the turntable to provide the attitudes of turntable mounting plat. Through this way, the high accuracy measurement of perpendicularity error and initial attitude of the three-axis turntable has been achieved.

  12. High-accuracy measurement and compensation of grating line-density error in a tiled-grating compressor

    Science.gov (United States)

    Zhao, Dan; Wang, Xiao; Mu, Jie; Li, Zhilin; Zuo, Yanlei; Zhou, Song; Zhou, Kainan; Zeng, Xiaoming; Su, Jingqin; Zhu, Qihua

    2017-02-01

    The grating tiling technology is one of the most effective means to increase the aperture of the gratings. The line-density error (LDE) between sub-gratings will degrade the performance of the tiling gratings, high accuracy measurement and compensation of the LDE are of significance to improve the output pulses characteristics of the tiled-grating compressor. In this paper, the influence of LDE on the output pulses of the tiled-grating compressor is quantitatively analyzed by means of numerical simulation, the output beams drift and output pulses broadening resulting from the LDE are presented. Based on the numerical results we propose a compensation method to reduce the degradations of the tiled grating compressor by applying angular tilt error and longitudinal piston error at the same time. Moreover, a monitoring system is setup to measure the LDE between sub-gratings accurately and the dispersion variation due to the LDE is also demonstrated based on spatial-spectral interference. In this way, we can realize high-accuracy measurement and compensation of the LDE, and this would provide an efficient way to guide the adjustment of the tiling gratings.

  13. Direct Calculation of Permeability by High-Accurate Finite Difference and Numerical Integration Methods

    KAUST Repository

    Wang, Yi

    2016-07-21

    Velocity of fluid flow in underground porous media is 6~12 orders of magnitudes lower than that in pipelines. If numerical errors are not carefully controlled in this kind of simulations, high distortion of the final results may occur [1-4]. To fit the high accuracy demands of fluid flow simulations in porous media, traditional finite difference methods and numerical integration methods are discussed and corresponding high-accurate methods are developed. When applied to the direct calculation of full-tensor permeability for underground flow, the high-accurate finite difference method is confirmed to have numerical error as low as 10-5% while the high-accurate numerical integration method has numerical error around 0%. Thus, the approach combining the high-accurate finite difference and numerical integration methods is a reliable way to efficiently determine the characteristics of general full-tensor permeability such as maximum and minimum permeability components, principal direction and anisotropic ratio. Copyright © Global-Science Press 2016.

  14. High accuracy velocity control method for the french moving-coil watt balance

    International Nuclear Information System (INIS)

    Topcu, Suat; Chassagne, Luc; Haddad, Darine; Alayli, Yasser; Juncar, Patrick

    2004-01-01

    We describe a novel method of velocity control dedicated to the French moving-coil watt balance. In this project, a coil has to move in a magnetic field at a velocity of 2 mm s -1 with a relative uncertainty of 10 -9 over 60 mm. Our method is based on the use of both a heterodyne Michelson's interferometer, a two-level translation stage, and a homemade high frequency phase-shifting electronic circuit. To quantify the stability of the velocity, the output of the interferometer is sent into a frequency counter and the Doppler frequency shift is recorded. The Allan standard deviation has been used to calculate the stability and a σ y (τ) of about 2.2x10 -9 over 400 s has been obtained

  15. Real-time and high accuracy frequency measurements for intermediate frequency narrowband signals

    Science.gov (United States)

    Tian, Jing; Meng, Xiaofeng; Nie, Jing; Lin, Liwei

    2018-01-01

    Real-time and accurate measurements of intermediate frequency signals based on microprocessors are difficult due to the computational complexity and limited time constraints. In this paper, a fast and precise methodology based on the sigma-delta modulator is designed and implemented by first generating the twiddle factors using the designed recursive scheme. This scheme requires zero times of multiplications and only half amounts of addition operations by using the discrete Fourier transform (DFT) and the combination of the Rife algorithm and Fourier coefficient interpolation as compared with conventional methods such as DFT and Fast Fourier Transform. Experimentally, when the sampling frequency is 10 MHz, the real-time frequency measurements with intermediate frequency and narrowband signals have a measurement mean squared error of ±2.4 Hz. Furthermore, a single measurement of the whole system only requires approximately 0.3 s to achieve fast iteration, high precision, and less calculation time.

  16. A high-accuracy image registration algorithm using phase-only correlation for dental radiographs

    International Nuclear Information System (INIS)

    Ito, Koichi; Nikaido, Akira; Aoki, Takafumi; Kosuge, Eiko; Kawamata, Ryota; Kashima, Isamu

    2008-01-01

    Dental radiographs have been used for the accurate assessment and treatment of dental diseases. The nonlinear deformation between two dental radiographs may be observed, even if they are taken from the same oral regions of the subject. For an accurate diagnosis, the complete geometric registration between radiographs is required. This paper presents an efficient dental radiograph registration algorithm using Phase-Only Correlation (POC) function. The use of phase components in 2D (two-dimensional) discrete Fourier transforms of dental radiograph images makes possible to achieve highly robust image registration and recognition. Experimental evaluation using a dental radiograph database indicates that the proposed algorithm exhibits efficient recognition performance even for distorted radiographs. (author)

  17. Combination volumetric and gravimetric sorption instrument for high accuracy measurements of methane adsorption

    Science.gov (United States)

    Burress, Jacob; Bethea, Donald; Troub, Brandon

    2017-05-01

    The accurate measurement of adsorbed gas up to high pressures (˜100 bars) is critical for the development of new materials for adsorbed gas storage. The typical Sievert-type volumetric method introduces accumulating errors that can become large at maximum pressures. Alternatively, gravimetric methods employing microbalances require careful buoyancy corrections. In this paper, we present a combination gravimetric and volumetric system for methane sorption measurements on samples between ˜0.5 and 1 g. The gravimetric method described requires no buoyancy corrections. The tandem use of the gravimetric method allows for a check on the highest uncertainty volumetric measurements. The sources and proper calculation of uncertainties are discussed. Results from methane measurements on activated carbon MSC-30 and metal-organic framework HKUST-1 are compared across methods and within the literature.

  18. Accuracy of W' Recovery Kinetics in High Performance Cyclists - Modelling Intermittent Work Capacity.

    Science.gov (United States)

    Bartram, Jason C; Thewlis, Dominic; Martin, David T; Norton, Kevin I

    2017-10-16

    With knowledge of an individual's critical power (CP) and W' the SKIBA 2 model provides a framework with which to track W' balance during intermittent high intensity work bouts. There are fears the time constant controlling the recovery rate of W' (τ W' ) may require refinement to enable effective use in an elite population. Four elite endurance cyclists completed an array of intermittent exercise protocols to volitional exhaustion. Each protocol lasted approximately 3.5-6 minutes and featured a range of recovery intensities, set in relation to athlete's CPs (DCP). Using the framework of the SKIBA 2 model, the τ W ' values were modified for each protocol to achieve an accurate W' at volitional exhaustion. Modified τ W ' values were compared to equivalent SKIBA 2 τ W ' values to assess the difference in recovery rates for this population. Plotting modified τ W ' values against DCP showed the adjusted relationship between work-rate and recovery-rate. Comparing modified τ W' values against the SKIBA 2 τ W' values showed a negative bias of 112±46s (mean±95%CL), suggesting athlete's recovered W' faster than predicted by SKIBA 2 (p=0.0001). The modified τ W' to DCP relationship was best described by a power function: τ W' =2287.2∗D CP -0.688 (R 2 = 0.433). The current SKIBA 2 model is not appropriate for use in elite cyclists as it under predicts the recovery rate of W'. The modified τ W' equation presented will require validation, but appears more appropriate for high performance athletes. Individual τ W' relationships may be necessary in order to maximise the model's validity.

  19. Accuracy of Administrative Codes for Distinguishing Positive Pressure Ventilation from High-Flow Nasal Cannula.

    Science.gov (United States)

    Good, Ryan J; Leroue, Matthew K; Czaja, Angela S

    2018-06-07

    Noninvasive positive pressure ventilation (NIPPV) is increasingly used in critically ill pediatric patients, despite limited data on safety and efficacy. Administrative data may be a good resource for observational studies. Therefore, we sought to assess the performance of the International Classification of Diseases, Ninth Revision procedure code for NIPPV. Patients admitted to the PICU requiring NIPPV or heated high-flow nasal cannula (HHFNC) over the 11-month study period were identified from the Virtual PICU System database. The gold standard was manual review of the electronic health record to verify the use of NIPPV or HHFNC among the cohort. The presence or absence of a NIPPV procedure code was determined by using administrative data. Test characteristics with 95% confidence intervals (CIs) were generated, comparing administrative data with the gold standard. Among the cohort ( n = 562), the majority were younger than 5 years, and the most common primary diagnosis was bronchiolitis. Most (82%) required NIPPV, whereas 18% required only HHFNC. The NIPPV code had a sensitivity of 91.1% (95% CI: 88.2%-93.6%) and a specificity of 57.6% (95% CI: 47.2%-67.5%), with a positive likelihood ratio of 2.15 (95% CI: 1.70-2.71) and negative likelihood ratio of 0.15 (95% CI: 0.11-0.22). Among our critically ill pediatric cohort, NIPPV procedure codes had high sensitivity but only moderate specificity. On the basis of our study results, there is a risk of misclassification, specifically failure to identify children who require NIPPV, when using administrative data to study the use of NIPPV in this population. Copyright © 2018 by the American Academy of Pediatrics.

  20. Cadastral Database Positional Accuracy Improvement

    Science.gov (United States)

    Hashim, N. M.; Omar, A. H.; Ramli, S. N. M.; Omar, K. M.; Din, N.

    2017-10-01

    Positional Accuracy Improvement (PAI) is the refining process of the geometry feature in a geospatial dataset to improve its actual position. This actual position relates to the absolute position in specific coordinate system and the relation to the neighborhood features. With the growth of spatial based technology especially Geographical Information System (GIS) and Global Navigation Satellite System (GNSS), the PAI campaign is inevitable especially to the legacy cadastral database. Integration of legacy dataset and higher accuracy dataset like GNSS observation is a potential solution for improving the legacy dataset. However, by merely integrating both datasets will lead to a distortion of the relative geometry. The improved dataset should be further treated to minimize inherent errors and fitting to the new accurate dataset. The main focus of this study is to describe a method of angular based Least Square Adjustment (LSA) for PAI process of legacy dataset. The existing high accuracy dataset known as National Digital Cadastral Database (NDCDB) is then used as bench mark to validate the results. It was found that the propose technique is highly possible for positional accuracy improvement of legacy spatial datasets.

  1. Integrated differential high-voltage transmitting circuit for CMUTs

    DEFF Research Database (Denmark)

    Llimos Muntal, Pere; Larsen, Dennis Øland; Farch, Kjartan

    2015-01-01

    In this paper an integrated differential high-voltage transmitting circuit for capacitive micromachined ultrasonic transducers (CMUTs) used in portable ultrasound scanners is designed and implemented in a 0.35 μm high-voltage process. Measurements are performed on the integrated circuit in order...... to assess its performance. The circuit generates pulses at differential voltage levels of 60V, 80V and 100 V, a frequency up to 5MHz and a measured driving strength of 1.75 V/ns with the CMUT connected. The total on-chip area occupied by the transmitting circuit is 0.18 mm2 and the power consumption...

  2. Determination of the QCD Λ-parameter and the accuracy of perturbation theory at high energies

    International Nuclear Information System (INIS)

    Dalla Brida, Mattia; Fritzsch, Patrick; Korzec, Tomasz; Ramos, Alberto; Sint, Stefan; Sommer, Rainer; Humboldt-Universitaet, Berlin

    2016-04-01

    We discuss the determination of the strong coupling α_M_S(m_Z) or equivalently the QCD Λ-parameter. Its determination requires the use of perturbation theory in α_s(μ) in some scheme, s, and at some energy scale μ. The higher the scale μ the more accurate perturbation theory becomes, owing to asymptotic freedom. As one step in our computation of the Λ-parameter in three-flavor QCD, we perform lattice computations in a scheme which allows us to non-perturbatively reach very high energies, corresponding to α_s=0.1 and below. We find that (continuum) perturbation theory is very accurate there, yielding a three percent error in the Λ-parameter, while data around α_s∼0.2 is clearly insufficient to quote such a precision. It is important to realize that these findings are expected to be generic, as our scheme has advantageous properties regarding the applicability of perturbation theory.

  3. Determination of the QCD Λ-parameter and the accuracy of perturbation theory at high energies

    Energy Technology Data Exchange (ETDEWEB)

    Dalla Brida, Mattia [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC; Fritzsch, Patrick [Univ. Autonoma de Madrid (Spain). Inst. de Fisica Teorica UAM/CSIC; Korzec, Tomasz [Wuppertal Univ. (Germany). Dept. of Physics; Ramos, Alberto [CERN - European Organization for Nuclear Research, Geneva (Switzerland). Theory Div.; Sint, Stefan [Trinity College Dublin (Ireland). School of Mathematics; Sommer, Rainer [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC; Humboldt-Universitaet, Berlin (Germany). Inst. fuer Physik; Collaboration: ALPHA Collaboration

    2016-04-15

    We discuss the determination of the strong coupling α{sub MS}(m{sub Z}) or equivalently the QCD Λ-parameter. Its determination requires the use of perturbation theory in α{sub s}(μ) in some scheme, s, and at some energy scale μ. The higher the scale μ the more accurate perturbation theory becomes, owing to asymptotic freedom. As one step in our computation of the Λ-parameter in three-flavor QCD, we perform lattice computations in a scheme which allows us to non-perturbatively reach very high energies, corresponding to α{sub s}=0.1 and below. We find that (continuum) perturbation theory is very accurate there, yielding a three percent error in the Λ-parameter, while data around α{sub s}∼0.2 is clearly insufficient to quote such a precision. It is important to realize that these findings are expected to be generic, as our scheme has advantageous properties regarding the applicability of perturbation theory.

  4. High-accuracy X-ray detector calibration based on cryogenic radiometry

    Science.gov (United States)

    Krumrey, M.; Cibik, L.; Müller, P.

    2010-06-01

    Cryogenic electrical substitution radiometers (ESRs) are absolute thermal detectors, based on the equivalence of electrical power and radiant power. Their core piece is a cavity absorber, which is typically made of copper to achieve a short response time. At higher photon energies, the use of copper prevents the operation of ESRs due to increasing transmittance. A new absorber design for hard X-rays has been developed at the laboratory of the Physikalisch-Technische Bundesanstalt (PTB) at the electron storage ring BESSY II. The Monte Carlo simulation code Geant4 was applied to optimize its absorptance for photon energies of up to 60 keV. The measurement of the radiant power of monochromatized synchrotron radiation was achieved with relative standard uncertainties of less than 0.2 %, covering the entire photon energy range of three beamlines from 50 eV to 60 keV. Monochromatized synchrotron radiation of high spectral purity is used to calibrate silicon photodiodes against the ESR for photon energies up to 60 keV with relative standard uncertainties below 0.3 %. For some silicon photodiodes, the photocurrent is not linear with the incident radiant power.

  5. High-accuracy X-ray detector calibration based on cryogenic radiometry

    International Nuclear Information System (INIS)

    Krumrey, M.; Cibik, L.; Mueller, P.

    2010-01-01

    Cryogenic electrical substitution radiometers (ESRs) are absolute thermal detectors, based on the equivalence of electrical power and radiant power. Their core piece is a cavity absorber, which is typically made of copper to achieve a short response time. At higher photon energies, the use of copper prevents the operation of ESRs due to increasing transmittance. A new absorber design for hard X-rays has been developed at the laboratory of the Physikalisch-Technische Bundesanstalt (PTB) at the electron storage ring BESSY II. The Monte Carlo simulation code Geant4 was applied to optimize its absorptance for photon energies of up to 60 keV. The measurement of the radiant power of monochromatized synchrotron radiation was achieved with relative standard uncertainties of less than 0.2 %, covering the entire photon energy range of three beamlines from 50 eV to 60 keV. Monochromatized synchrotron radiation of high spectral purity is used to calibrate silicon photodiodes against the ESR for photon energies up to 60 keV with relative standard uncertainties below 0.3 %. For some silicon photodiodes, the photocurrent is not linear with the incident radiant power.

  6. High-accuracy local positioning network for the alignment of the Mu2e experiment.

    Energy Technology Data Exchange (ETDEWEB)

    Hejdukova, Jana B. [Czech Technical Univ., Prague (Czech Republic)

    2017-06-01

    This Diploma thesis describes the establishment of a high-precision local positioning network and accelerator alignment for the Mu2e physics experiment. The process of establishing new network consists of few steps: design of the network, pre-analysis, installation works, measurements of the network and making adjustments. Adjustments were performed using two approaches. First is a geodetic approach of taking into account the Earth’s curvature and the metrological approach of a pure 3D Cartesian system on the other side. The comparison of those two approaches is performed and evaluated in the results and compared with expected differences. The effect of the Earth’s curvature was found to be significant for this kind of network and should not be neglected. The measurements were obtained with Absolute Tracker AT401, leveling instrument Leica DNA03 and gyrotheodolite DMT Gyromat 2000. The coordinates of the points of the reference network were determined by the Least Square Meth od and the overall view is attached as Annexes.

  7. Diagnostic accuracy for X-ray chest in interstitial lung disease as confirmed by high resolution computed tomography (HRCT) chest

    International Nuclear Information System (INIS)

    Afzal, F.; Raza, S.; Shafique, M.

    2017-01-01

    Objective: To determine the diagnostic accuracy of x-ray chest in interstitial lung disease as confirmed by high resolution computed tomography (HRCT) chest. Study Design: A cross-sectional validational study. Place and Duration of Study: Department of Diagnostic Radiology, Combined Military Hospital Rawalpindi, from Oct 2013 to Apr 2014. Material and Method: A total of 137 patients with clinical suspicion of interstitial lung disease (ILD) aged 20-50 years of both genders were included in the study. Patients with h/o previous histopathological diagnosis, already taking treatment and pregnant females were excluded. All the patients had chest x-ray and then HRCT. The x-ray and HRCT findings were recorded as presence or absence of the ILD. Results: Mean age was 40.21 ± 4.29 years. Out of 137 patients, 79 (57.66 percent) were males and 58 (42.34 percent) were females with male to female ratio of 1.36:1. Chest x-ray detected ILD in 80 (58.39 percent) patients, out of which, 72 (true positive) had ILD and 8 (false positive) had no ILD on HRCT. Overall sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of chest x-ray in diagnosing ILD was 80.0 percent, 82.98 percent, 90.0 percent, 68.42 percent and 81.02 percent respectively. Conclusion: This study concluded that chest x-ray is simple, non-invasive, economical and readily available alternative to HRCT with an acceptable diagnostic accuracy of 81 percent in the diagnosis of ILD. (author)

  8. Social power and recognition of emotional prosody: High power is associated with lower recognition accuracy than low power.

    Science.gov (United States)

    Uskul, Ayse K; Paulmann, Silke; Weick, Mario

    2016-02-01

    Listeners have to pay close attention to a speaker's tone of voice (prosody) during daily conversations. This is particularly important when trying to infer the emotional state of the speaker. Although a growing body of research has explored how emotions are processed from speech in general, little is known about how psychosocial factors such as social power can shape the perception of vocal emotional attributes. Thus, the present studies explored how social power affects emotional prosody recognition. In a correlational study (Study 1) and an experimental study (Study 2), we show that high power is associated with lower accuracy in emotional prosody recognition than low power. These results, for the first time, suggest that individuals experiencing high or low power perceive emotional tone of voice differently. (c) 2016 APA, all rights reserved).

  9. High-accuracy detection of early Parkinson's Disease using multiple characteristics of finger movement while typing.

    Directory of Open Access Journals (Sweden)

    Warwick R Adams

    Full Text Available Parkinson's Disease (PD is a progressive neurodegenerative movement disease affecting over 6 million people worldwide. Loss of dopamine-producing neurons results in a range of both motor and non-motor symptoms, however there is currently no definitive test for PD by non-specialist clinicians, especially in the early disease stages where the symptoms may be subtle and poorly characterised. This results in a high misdiagnosis rate (up to 25% by non-specialists and people can have the disease for many years before diagnosis. There is a need for a more accurate, objective means of early detection, ideally one which can be used by individuals in their home setting. In this investigation, keystroke timing information from 103 subjects (comprising 32 with mild PD severity and the remainder non-PD controls was captured as they typed on a computer keyboard over an extended period and showed that PD affects various characteristics of hand and finger movement and that these can be detected. A novel methodology was used to classify the subjects' disease status, by utilising a combination of many keystroke features which were analysed by an ensemble of machine learning classification models. When applied to two separate participant groups, this approach was able to successfully discriminate between early-PD subjects and controls with 96% sensitivity, 97% specificity and an AUC of 0.98. The technique does not require any specialised equipment or medical supervision, and does not rely on the experience and skill of the practitioner. Regarding more general application, it currently does not incorporate a second cardinal disease symptom, so may not differentiate PD from similar movement-related disorders.

  10. A diabetes dashboard and physician efficiency and accuracy in accessing data needed for high-quality diabetes care.

    Science.gov (United States)

    Koopman, Richelle J; Kochendorfer, Karl M; Moore, Joi L; Mehr, David R; Wakefield, Douglas S; Yadamsuren, Borchuluun; Coberly, Jared S; Kruse, Robin L; Wakefield, Bonnie J; Belden, Jeffery L

    2011-01-01

    We compared use of a new diabetes dashboard screen with use of a conventional approach of viewing multiple electronic health record (EHR) screens to find data needed for ambulatory diabetes care. We performed a usability study, including a quantitative time study and qualitative analysis of information-seeking behaviors. While being recorded with Morae Recorder software and "think-aloud" interview methods, 10 primary care physicians first searched their EHR for 10 diabetes data elements using a conventional approach for a simulated patient, and then using a new diabetes dashboard for another. We measured time, number of mouse clicks, and accuracy. Two coders analyzed think-aloud and interview data using grounded theory methodology. The mean time needed to find all data elements was 5.5 minutes using the conventional approach vs 1.3 minutes using the diabetes dashboard (P dashboard (P dashboard (P dashboard improves both the efficiency and accuracy of acquiring data needed for high-quality diabetes care. Usability analysis tools can provide important insights into the value of optimizing physician use of health information technologies.

  11. High-accuracy self-calibration method for dual-axis rotation-modulating RLG-INS

    Science.gov (United States)

    Wei, Guo; Gao, Chunfeng; Wang, Qi; Wang, Qun; Long, Xingwu

    2017-05-01

    Inertial navigation system has been the core component of both military and civil navigation systems. Dual-axis rotation modulation can completely eliminate the inertial elements constant errors of the three axes to improve the system accuracy. But the error caused by the misalignment angles and the scale factor error cannot be eliminated through dual-axis rotation modulation. And discrete calibration method cannot fulfill requirements of high-accurate calibration of the mechanically dithered ring laser gyroscope navigation system with shock absorbers. This paper has analyzed the effect of calibration error during one modulated period and presented a new systematic self-calibration method for dual-axis rotation-modulating RLG-INS. Procedure for self-calibration of dual-axis rotation-modulating RLG-INS has been designed. The results of self-calibration simulation experiment proved that: this scheme can estimate all the errors in the calibration error model, the calibration precision of the inertial sensors scale factor error is less than 1ppm and the misalignment is less than 5″. These results have validated the systematic self-calibration method and proved its importance for accuracy improvement of dual -axis rotation inertial navigation system with mechanically dithered ring laser gyroscope.

  12. Thermionic integrated circuit technology for high power space applications

    International Nuclear Information System (INIS)

    Yadavalli, S.R.

    1984-01-01

    Thermionic triode and integrated circuit technology is in its infancy and it is emerging. The Thermionic triode can operate at relatively high voltages (up to 2000V) and at least tens of amperes. These devices, including their use in integrated circuitry, operate at high temperatures (800 0 C) and are very tolerant to nuclear and other radiations. These properties can be very useful in large space power applications such as that represented by the SP-100 system which uses a nuclear reactor. This paper presents an assessment of the application of thermionic integrated circuitry with space nuclear power system technology. A comparison is made with conventional semiconductor circuitry considering a dissipative shunt regulator for SP-100 type nuclear power system rated at 100 kW. The particular advantages of thermionic circuitry are significant reductions in size and mass of heat dissipation and radiation shield subsystems

  13. High-order boundary integral equation solution of high frequency wave scattering from obstacles in an unbounded linearly stratified medium

    Science.gov (United States)

    Barnett, Alex H.; Nelson, Bradley J.; Mahoney, J. Matthew

    2015-09-01

    We apply boundary integral equations for the first time to the two-dimensional scattering of time-harmonic waves from a smooth obstacle embedded in a continuously-graded unbounded medium. In the case we solve, the square of the wavenumber (refractive index) varies linearly in one coordinate, i.e. (Δ + E +x2) u (x1 ,x2) = 0 where E is a constant; this models quantum particles of fixed energy in a uniform gravitational field, and has broader applications to stratified media in acoustics, optics and seismology. We evaluate the fundamental solution efficiently with exponential accuracy via numerical saddle-point integration, using the truncated trapezoid rule with typically 102 nodes, with an effort that is independent of the frequency parameter E. By combining with a high-order Nyström quadrature, we are able to solve the scattering from obstacles 50 wavelengths across to 11 digits of accuracy in under a minute on a desktop or laptop.

  14. The Design of Integrated Information System for High Voltage Metering Lab

    Science.gov (United States)

    Ma, Yan; Yang, Yi; Xu, Guangke; Gu, Chao; Zou, Lida; Yang, Feng

    2018-01-01

    With the development of smart grid, intelligent and informatization management of high-voltage metering lab become increasingly urgent. In the paper we design an integrated information system, which automates the whole transactions from accepting instruments, make experiments, generating report, report signature to instrument claims. Through creating database for all the calibrated instruments, using two-dimensional code, integrating report templates in advance, establishing bookmarks and online transmission of electronical signatures, our manual procedures reduce largely. These techniques simplify the complex process of account management and report transmission. After more than a year of operation, our work efficiency improves about forty percent averagely, and its accuracy rate and data reliability are much higher as well.

  15. Location accuracy evaluation of lightning location systems using natural lightning flashes recorded by a network of high-speed cameras

    Science.gov (United States)

    Alves, J.; Saraiva, A. C. V.; Campos, L. Z. D. S.; Pinto, O., Jr.; Antunes, L.

    2014-12-01

    This work presents a method for the evaluation of location accuracy of all Lightning Location System (LLS) in operation in southeastern Brazil, using natural cloud-to-ground (CG) lightning flashes. This can be done through a multiple high-speed cameras network (RAMMER network) installed in the Paraiba Valley region - SP - Brazil. The RAMMER network (Automated Multi-camera Network for Monitoring and Study of Lightning) is composed by four high-speed cameras operating at 2,500 frames per second. Three stationary black-and-white (B&W) cameras were situated in the cities of São José dos Campos and Caçapava. A fourth color camera was mobile (installed in a car), but operated in a fixed location during the observation period, within the city of São José dos Campos. The average distance among cameras was 13 kilometers. Each RAMMER sensor position was determined so that the network can observe the same lightning flash from different angles and all recorded videos were GPS (Global Position System) time stamped, allowing comparisons of events between cameras and the LLS. The RAMMER sensor is basically composed by a computer, a Phantom high-speed camera version 9.1 and a GPS unit. The lightning cases analyzed in the present work were observed by at least two cameras, their position was visually triangulated and the results compared with BrasilDAT network, during the summer seasons of 2011/2012 and 2012/2013. The visual triangulation method is presented in details. The calibration procedure showed an accuracy of 9 meters between the accurate GPS position of the object triangulated and the result from the visual triangulation method. Lightning return stroke positions, estimated with the visual triangulation method, were compared with LLS locations. Differences between solutions were not greater than 1.8 km.

  16. Assessment of high precision, high accuracy Inductively Coupled Plasma-Optical Emission Spectroscopy to obtain concentration uncertainties less than 0.2% with variable matrix concentrations

    International Nuclear Information System (INIS)

    Rabb, Savelas A.; Olesik, John W.

    2008-01-01

    The ability to obtain high precision, high accuracy measurements in samples with complex matrices using High Performance Inductively Coupled Plasma-Optical Emission Spectroscopy (HP-ICP-OES) was investigated. The Common Analyte Internal Standard (CAIS) procedure was incorporated into the High Performance Inductively Coupled Plasma-Optical Emission Spectroscopy method to correct for matrix-induced changes in emission intensity ratios. Matrix matching and standard addition approaches to minimize matrix-induced errors when using High Performance Inductively Coupled Plasma-Optical Emission Spectroscopy were also assessed. The High Performance Inductively Coupled Plasma-Optical Emission Spectroscopy method was tested with synthetic solutions in a variety of matrices, alloy standard reference materials and geological reference materials

  17. Audiovisual integration of speech falters under high attention demands.

    Science.gov (United States)

    Alsius, Agnès; Navarra, Jordi; Campbell, Ruth; Soto-Faraco, Salvador

    2005-05-10

    One of the most commonly cited examples of human multisensory integration occurs during exposure to natural speech, when the vocal and the visual aspects of the signal are integrated in a unitary percept. Audiovisual association of facial gestures and vocal sounds has been demonstrated in nonhuman primates and in prelinguistic children, arguing for a general basis for this capacity. One critical question, however, concerns the role of attention in such multisensory integration. Although both behavioral and neurophysiological studies have converged on a preattentive conceptualization of audiovisual speech integration, this mechanism has rarely been measured under conditions of high attentional load, when the observers' attention resources are depleted. We tested the extent to which audiovisual integration was modulated by the amount of available attentional resources by measuring the observers' susceptibility to the classic McGurk illusion in a dual-task paradigm. The proportion of visually influenced responses was severely, and selectively, reduced if participants were concurrently performing an unrelated visual or auditory task. In contrast with the assumption that crossmodal speech integration is automatic, our results suggest that these multisensory binding processes are subject to attentional demands.

  18. Radiation response of high speed CMOS integrated circuits

    International Nuclear Information System (INIS)

    Yue, H.; Davison, D.; Jennings, R.F.; Lothongkam, P.; Rinerson, D.; Wyland, D.

    1987-01-01

    This paper studies the total dose and dose rate radiation response of the FCT family of high speed CMOS integrated circuits. Data taken on the devices is used to establish the dominant failure modes, and this data is further analyzed using one-sided tolerance factors for normal distribution statistical analysis

  19. The design of high performance weak current integrated amplifier

    International Nuclear Information System (INIS)

    Chen Guojie; Cao Hui

    2005-01-01

    A design method of high performance weak current integrated amplifier using ICL7650 operational amplifier is introduced. The operating principle of circuits and the step of improving amplifier's performance are illustrated. Finally, the experimental results are given. The amplifier has programmable measurement range of 10 -9 -10 -12 A, automatic zero-correction, accurate measurement, and good stability. (authors)

  20. Heat sinking of highly integrated photonic and electronic circuits

    NARCIS (Netherlands)

    van Rijn, M.B.J.; Smit, M.K.

    2017-01-01

    Dense integration of photonic and electronic circuits poses high requirements on thermal management. In this paper we present analysis of temperature distributions in PICs in InP membranes on top of a BiCMOS chip, which contain hot spots in both the photonic and the electronic layer (lasers, optical

  1. INCORPORATION OF DNA BARCODES INTO ASSESSMENTS OF THE BIOLOGICAL INTEGRITY OF AQUATIC ECOSYSTEMS: PRECISION, ACCURACY AND COST

    Science.gov (United States)

    Historically, water quality assessments in the United States primarily focused on water chemistry assays at or near discharge sources. As it has become clear that waters also can be highly impaired from dispersed (i.e., non-point source) chemicals and non-chemical impacts, direc...

  2. Integrated computer network high-speed parallel interface

    International Nuclear Information System (INIS)

    Frank, R.B.

    1979-03-01

    As the number and variety of computers within Los Alamos Scientific Laboratory's Central Computer Facility grows, the need for a standard, high-speed intercomputer interface has become more apparent. This report details the development of a High-Speed Parallel Interface from conceptual through implementation stages to meet current and future needs for large-scle network computing within the Integrated Computer Network. 4 figures

  3. Simplifying and expanding analytical capabilities for various classes of doping agents by means of direct urine injection high performance liquid chromatography high resolution/high accuracy mass spectrometry.

    Science.gov (United States)

    Görgens, Christian; Guddat, Sven; Thomas, Andreas; Wachsmuth, Philipp; Orlovius, Anne-Katrin; Sigmund, Gerd; Thevis, Mario; Schänzer, Wilhelm

    2016-11-30

    So far, in sports drug testing compounds of different classes are processed and measured using different screening procedures. The constantly increasing number of samples in doping analysis, as well as the large number of substances with doping related, pharmacological effects require the development of even more powerful assays than those already employed in sports drug testing, indispensably with reduced sample preparation procedures. The analysis of native urine samples after direct injection provides a promising analytical approach, which thereby possesses a broad applicability to many different compounds and their metabolites, without a time-consuming sample preparation. In this study, a novel multi-target approach based on liquid chromatography and high resolution/high accuracy mass spectrometry is presented to screen for more than 200 analytes of various classes of doping agents far below the required detection limits in sports drug testing. Here, classic groups of drugs as diuretics, stimulants, β 2 -agonists, narcotics and anabolic androgenic steroids as well as various newer target compounds like hypoxia-inducible factor (HIF) stabilizers, selective androgen receptor modulators (SARMs), selective estrogen receptor modulators (SERMs), plasma volume expanders and other doping related compounds, listed in the 2016 WADA prohibited list were implemented. As a main achievement, growth hormone releasing peptides could be implemented, which chemically belong to the group of small peptides (0.99), limit of detection (0.1-25ng/mL; 3'OH-stanozolol glucuronide: 50pg/mL; dextran/HES: 10μg/mL) and matrix effects. Copyright © 2016 Elsevier B.V. All rights reserved.

  4. The linear interplay of intrinsic and extrinsic noises ensures a high accuracy of cell fate selection in budding yeast

    Science.gov (United States)

    Li, Yongkai; Yi, Ming; Zou, Xiufen

    2014-01-01

    To gain insights into the mechanisms of cell fate decision in a noisy environment, the effects of intrinsic and extrinsic noises on cell fate are explored at the single cell level. Specifically, we theoretically define the impulse of Cln1/2 as an indication of cell fates. The strong dependence between the impulse of Cln1/2 and cell fates is exhibited. Based on the simulation results, we illustrate that increasing intrinsic fluctuations causes the parallel shift of the separation ratio of Whi5P but that increasing extrinsic fluctuations leads to the mixture of different cell fates. Our quantitative study also suggests that the strengths of intrinsic and extrinsic noises around an approximate linear model can ensure a high accuracy of cell fate selection. Furthermore, this study demonstrates that the selection of cell fates is an entropy-decreasing process. In addition, we reveal that cell fates are significantly correlated with the range of entropy decreases. PMID:25042292

  5. A direct indication of plasma potential diagnostic with fast time response and high accuracy based on a differential emissive probe

    International Nuclear Information System (INIS)

    Yao, W.E.; Hershkowitz; Intrator, T.

    1985-01-01

    The floating potential of the emissive probe has been used to directly measure the plasma potential. The authors have recently presented another method for directly indicating the plasma potential with a differential emissive probe. In this paper they describe the effects of probe size, plasma density and plasma potential fluctuation on plasma potential measurements and give methods for reducing errors. A control system with fast time response (α 20 μs) and high accuracy (the order of the probe temperature T/sub w//e) for maintaining a differential emissive probe at plasma potential has been developed. It can be operated in pulsed discharge plasma to measure plasma potential dynamic characteristics. A solid state optical coupler is employed to improve circuit performance. This system was tested experimentally by measuring the plasma potential in an argon plasma device an on the Phaedrus tandem mirror

  6. A high-accuracy extraction of the isoscalar πN scattering length from pionic deuterium data

    International Nuclear Information System (INIS)

    Phillips, Daniel R.; Baru, Vadim; Hanhart, Christoph; Nogga, Andreas; Hoferichter, Martin; Kubis, Bastian

    2010-01-01

    We present a high-accuracy calculation of the π(bar sign)d scattering length using chiral perturbation theory up to order (M π /m p ) 7/2 . For the first time isospin-violating corrections are included consistently. The resulting value of a π -bar d has a theoretical uncertainty of a few percent. We use it, together with data on pionic deuterium and pionic hydrogen atoms, to extract the isoscalar and isovector pion-nucleon scattering lengths from a combined analysis, and obtain a + (7.9±3.2)·10 -3 M π -1 and a-bar (86.3±1.0)·10 -3 M π -1 .

  7. A direct indication of plasma potential diagnostic with fast time response and high accuracy based on a differential emissive probe

    International Nuclear Information System (INIS)

    Yao, W.E.; Hershkowitz, N.; Intrator, T.

    1985-01-01

    The floating potential of the emissive probe has been used to directly measure the plasma potential. The authors have recently presented another method for directly indicating the plasma potential with a differential emissive probe. In this paper they describe the effects of probe size, plasma density and plasma potential fluctuation on plasma potential measurements and give methods for reducing errors. A control system with fast time response (≅ 20 μs) and high accuracy (the order of the probe temperature T/sub w//e) for maintaining a differential emissive probe at plasma potential has been developed. It can be operated in pulsed discharge plasma to measure plasma potential dynamic characteristics. A solid state optical coupler is employed to improve circuit performance. This system was tested experimentally by measuring the plasma potential in an argon plasma device and on the Phaedrus tandem mirror

  8. High accuracy determination of trace elements in NIST standard reference materials by isotope dilution ICP-MS

    International Nuclear Information System (INIS)

    Paulsen, P.J.; Beary, E.S.

    1996-01-01

    At NIST (National Institute of Standards and Technology), ICP-MS ID (inductively coupled mass spectrometry isotope dilution) has been used to certify a wide range of elements in a variety of materials with high accuracy. Both the chemical preparation and instrumental procedures are simpler than with other ID mass spectrometric techniques. The ICP-MS has picogram/ml detection limits for most elements using fixed operating parameters. Chemical separations are required only to remove an interference (from molecular ions as well as isobaric atoms), or to pre-concentrate the analyte. For example, chemical separations were required for the analysis of SRM 2711, Montana II Soil, but not for boron in peach leaves, SRM 1547.(3 refs., 3 tabs., 2 figs

  9. High throughput platforms for structural genomics of integral membrane proteins.

    Science.gov (United States)

    Mancia, Filippo; Love, James

    2011-08-01

    Structural genomics approaches on integral membrane proteins have been postulated for over a decade, yet specific efforts are lagging years behind their soluble counterparts. Indeed, high throughput methodologies for production and characterization of prokaryotic integral membrane proteins are only now emerging, while large-scale efforts for eukaryotic ones are still in their infancy. Presented here is a review of recent literature on actively ongoing structural genomics of membrane protein initiatives, with a focus on those aimed at implementing interesting techniques aimed at increasing our rate of success for this class of macromolecules. Copyright © 2011 Elsevier Ltd. All rights reserved.

  10. Integrated High-Rate Transition Radiation Detector and Tracking Chamber for the LHC

    CERN Multimedia

    2002-01-01

    % RD-6 \\\\ \\\\Over the past five years, RD-6 has developed a transition radiation detector and charged particle tracker for high rate operation at LHC. The detector elements are based on C-fibre reinforced kapton straw tubes of 4~mm diameter filled with a Xenon gas mixture. Detailed measurements with and without magnetic field have been performed in test beams, and in particular have demonstrated the possibility of operating straw tubes at very high rate (up to 20~MHz) with accurate drift-time measurement accuracy. A full-scale engineering prototype containing 10~000 straws is presently under assembly and will be accurately measured with a powerful X-ray tube. Integrated front-end electronics with fast readout have been designed and successfully operated in test beam. \\\\ \\\\Finally extensive simulations performed for ATLAS have shown that such a detector will provide powerful pattern recognition, accurate momentum measurements, efficient level-2 triggering and excellent electron identification, even at the highe...

  11. Integrative Production Technology for High-Wage Countries

    CERN Document Server

    2012-01-01

    Industrial production in high-wage countries like Germany is still at risk. Yet, there are many counter-examples in which producing companies dominate their competitors by not only compensating for their specific disadvantages in terms of factor costs (e.g. wages, energy, duties and taxes) but rather by minimising waste using synchronising integrativity as well as by obtaining superior adaptivity on alternating conditions. In order to respond to the issue of economic sustainability of industrial production in high-wage countries, the leading production engineering and material research scientists of RWTH Aachen University together with renowned companies have established the Cluster of Excellence “Integrative Production Technology for High-Wage Countries”. This compendium comprises the cluster’s scientific results as well as a selection of business and technology cases, in which these results have been successfully implemented into industrial practice in close cooperation with more than 30 companies of ...

  12. Fully integrated CMOS pixel detector for high energy particles

    International Nuclear Information System (INIS)

    Vanstraelen, G.; Debusschere, I.; Claeys, C.; Declerck, G.

    1989-01-01

    A novel type of position and energy sensitive, monolithic pixel array with integrated readout electronics is proposed. Special features of the design are a reduction of the number of output channels and of the amount of output data, and the use of transistors on the high resistivity silicon. The number of output channels for the detector array is reduced by handling in parallel a number of pixels, chosen as a function of the time resolution required for the system, and by the use of an address decoder. A further reduction of data is achieved by reading out only those pixels which have been activated. The pixel detector circuit will be realized in a 3 μm p-well CMOS process, which is optimized for the full integration of readout electronics and detector diodes on high resistivity Si. A retrograde well is formed by means of a high energy implantation, followed by the appropriate temperature steps. The optimization of the well shape takes into account the high substrate bias applied during the detector operation. The design is largely based on the use of MOS transistors on the high resistivity silicon itself. These have proven to perform as well as transistors on standard doped substrate. The basic building elements as well as the design strategy of the integrated pixel detector are presented in detail. (orig.)

  13. Snow cover volumes dynamic monitoring during melting season using high topographic accuracy approach for a Lebanese high plateau witness sinkhole

    Science.gov (United States)

    Abou Chakra, Charbel; Somma, Janine; Elali, Taha; Drapeau, Laurent

    2017-04-01

    Climate change and its negative impact on water resource is well described. For countries like Lebanon, undergoing major population's rise and already decreasing precipitations issues, effective water resources management is crucial. Their continuous and systematic monitoring overs long period of time is therefore an important activity to investigate drought risk scenarios for the Lebanese territory. Snow cover on Lebanese mountains is the most important water resources reserve. Consequently, systematic observation of snow cover dynamic plays a major role in order to support hydrologic research with accurate data on snow cover volumes over the melting season. For the last 20 years few studies have been conducted for Lebanese snow cover. They were focusing on estimating the snow cover surface using remote sensing and terrestrial measurement without obtaining accurate maps for the sampled locations. Indeed, estimations of both snow cover area and volumes are difficult due to snow accumulation very high variability and Lebanese mountains chains slopes topographic heterogeneity. Therefore, the snow cover relief measurement in its three-dimensional aspect and its Digital Elevation Model computation is essential to estimate snow cover volume. Despite the need to cover the all lebanese territory, we favored experimental terrestrial topographic site approaches due to high resolution satellite imagery cost, its limited accessibility and its acquisition restrictions. It is also most challenging to modelise snow cover at national scale. We therefore, selected a representative witness sinkhole located at Ouyoun el Siman to undertake systematic and continuous observations based on topographic approach using a total station. After four years of continuous observations, we acknowledged the relation between snow melt rate, date of total melting and neighboring springs discharges. Consequently, we are able to forecast, early in the season, dates of total snowmelt and springs low

  14. High-accuracy vibration sensor based on a Fabry-Perot interferometer with active phase-tracking technology.

    Science.gov (United States)

    Xia, Wei; Li, Chuncheng; Hao, Hui; Wang, Yiping; Ni, Xiaoqi; Guo, Dongmei; Wang, Ming

    2018-02-01

    A novel position-sensitive Fabry-Perot interferometer was constructed with direct phase modulation by a built-in electro-optic modulator. Pure sinusoidal phase modulation of the light was produced, and the first harmonic of the interference signal was extracted to dynamically maintain the interferometer phase to the most sensitive point of the interferogram. Therefore, the minute vibration of the object was coded on the variation of the interference signal and could be directly retrieved by the output voltage of a photodetector. The operating principle and the signal processing method for active feedback control of the interference phase have been demonstrated in detail. The developed vibration sensor was calibrated through a high-precision piezo-electric transducer and tested by a nano-positioning stage under a vibration magnitude of 60 nm and a frequency of 300 Hz. The active phase-tracking method of the system provides high immunity against environmental disturbances. Experimental results show that the proposed interferometer can effectively reconstruct tiny vibration waveforms with subnanometer resolution, paving the way for high-accuracy vibration sensing, especially for micro-electro-mechanical systems/nano-electro-mechanical systems and ultrasonic devices.

  15. High-Accuracy Tidal Flat Digital Elevation Model Construction Using TanDEM-X Science Phase Data

    Science.gov (United States)

    Lee, Seung-Kuk; Ryu, Joo-Hyung

    2017-01-01

    This study explored the feasibility of using TanDEM-X (TDX) interferometric observations of tidal flats for digital elevation model (DEM) construction. Our goal was to generate high-precision DEMs in tidal flat areas, because accurate intertidal zone data are essential for monitoring coastal environment sand erosion processes. To monitor dynamic coastal changes caused by waves, currents, and tides, very accurate DEMs with high spatial resolution are required. The bi- and monostatic modes of the TDX interferometer employed during the TDX science phase provided a great opportunity for highly accurate intertidal DEM construction using radar interferometry with no time lag (bistatic mode) or an approximately 10-s temporal baseline (monostatic mode) between the master and slave synthetic aperture radar image acquisitions. In this study, DEM construction in tidal flat areas was first optimized based on the TDX system parameters used in various TDX modes. We successfully generated intertidal zone DEMs with 57-m spatial resolutions and interferometric height accuracies better than 0.15 m for three representative tidal flats on the west coast of the Korean Peninsula. Finally, we validated these TDX DEMs against real-time kinematic-GPS measurements acquired in two tidal flat areas; the correlation coefficient was 0.97 with a root mean square error of 0.20 m.

  16. Highly integrated optical phased arrays: photonic integrated circuits for optical beam shaping and beam steering

    Science.gov (United States)

    Heck, Martijn J. R.

    2017-01-01

    Technologies for efficient generation and fast scanning of narrow free-space laser beams find major applications in three-dimensional (3D) imaging and mapping, like Lidar for remote sensing and navigation, and secure free-space optical communications. The ultimate goal for such a system is to reduce its size, weight, and power consumption, so that it can be mounted on, e.g. drones and autonomous cars. Moreover, beam scanning should ideally be done at video frame rates, something that is beyond the capabilities of current opto-mechanical systems. Photonic integrated circuit (PIC) technology holds the promise of achieving low-cost, compact, robust and energy-efficient complex optical systems. PICs integrate, for example, lasers, modulators, detectors, and filters on a single piece of semiconductor, typically silicon or indium phosphide, much like electronic integrated circuits. This technology is maturing fast, driven by high-bandwidth communications applications, and mature fabrication facilities. State-of-the-art commercial PICs integrate hundreds of elements, and the integration of thousands of elements has been shown in the laboratory. Over the last few years, there has been a considerable research effort to integrate beam steering systems on a PIC, and various beam steering demonstrators based on optical phased arrays have been realized. Arrays of up to thousands of coherent emitters, including their phase and amplitude control, have been integrated, and various applications have been explored. In this review paper, I will present an overview of the state of the art of this technology and its opportunities, illustrated by recent breakthroughs.

  17. Highly integrated optical phased arrays: photonic integrated circuits for optical beam shaping and beam steering

    Directory of Open Access Journals (Sweden)

    Heck Martijn J.R.

    2016-06-01

    Full Text Available Technologies for efficient generation and fast scanning of narrow free-space laser beams find major applications in three-dimensional (3D imaging and mapping, like Lidar for remote sensing and navigation, and secure free-space optical communications. The ultimate goal for such a system is to reduce its size, weight, and power consumption, so that it can be mounted on, e.g. drones and autonomous cars. Moreover, beam scanning should ideally be done at video frame rates, something that is beyond the capabilities of current opto-mechanical systems. Photonic integrated circuit (PIC technology holds the promise of achieving low-cost, compact, robust and energy-efficient complex optical systems. PICs integrate, for example, lasers, modulators, detectors, and filters on a single piece of semiconductor, typically silicon or indium phosphide, much like electronic integrated circuits. This technology is maturing fast, driven by high-bandwidth communications applications, and mature fabrication facilities. State-of-the-art commercial PICs integrate hundreds of elements, and the integration of thousands of elements has been shown in the laboratory. Over the last few years, there has been a considerable research effort to integrate beam steering systems on a PIC, and various beam steering demonstrators based on optical phased arrays have been realized. Arrays of up to thousands of coherent emitters, including their phase and amplitude control, have been integrated, and various applications have been explored. In this review paper, I will present an overview of the state of the art of this technology and its opportunities, illustrated by recent breakthroughs.

  18. CMOS-compatible high-voltage integrated circuits

    Energy Technology Data Exchange (ETDEWEB)

    Parpia, Z

    1988-01-01

    Considerable savings in cost and development time can be achieved if high-voltage ICs (HVICs) are fabricated in an existing low-voltage process. In this thesis, the feasibility of fabricating HVICs in a standard CMOS process is investigated. The high-voltage capabilities of an existing 5-{mu}m CMOS process are first studied. High-voltage n- and p-channel transistors with breakdown voltages of 50 and 190 V, respectively, were fabricated without any modifications to the process under consideration. SPICE models for these transistors are developed, and their accuracy verified by comparison with experimental results. In addition, the effect of the interconnect metallization on the high-voltage performance of these devices is also examined. Polysilicon field plates are found to be effective in preventing premature interconnect induced breakdown in these devices. A novel high-voltage transistor structure, the insulated base transistor (IBT), based on a merged MOS-bipolar concept, is proposed and implemented. In order to enhance the high-voltage device capabilities, an improved CMOS-compatible HVIC process using junction isolation is developed.

  19. THE IMPACT OF MODERATE AND HIGH INTENSITY TOTAL BODY FATIGUE ON PASSING ACCURACY IN EXPERT AND NOVICE BASKETBALL PLAYERS

    Directory of Open Access Journals (Sweden)

    Mark Lyons

    2006-06-01

    Full Text Available Despite the acknowledged importance of fatigue on performance in sport, ecologically sound studies investigating fatigue and its effects on sport-specific skills are surprisingly rare. The aim of this study was to investigate the effect of moderate and high intensity total body fatigue on passing accuracy in expert and novice basketball players. Ten novice basketball players (age: 23.30 ± 1.05 yrs and ten expert basketball players (age: 22.50 ± 0.41 yrs volunteered to participate in the study. Both groups performed the modified AAHPERD Basketball Passing Test under three different testing conditions: rest, moderate intensity and high intensity total body fatigue. Fatigue intensity was established using a percentage of the maximal number of squat thrusts performed by the participant in one minute. ANOVA with repeated measures revealed a significant (F 2,36 = 5.252, p = 0.01 level of fatigue by level of skill interaction. On examination of the mean scores it is clear that following high intensity total body fatigue there is a significant detriment in the passing performance of both novice and expert basketball players when compared to their resting scores. Fundamentally however, the detrimental impact of fatigue on passing performance is not as steep in the expert players compared to the novice players. The results suggest that expert or skilled players are better able to cope with both moderate and high intensity fatigue conditions and maintain a higher level of performance when compared to novice players. The findings of this research therefore, suggest the need for trainers and conditioning coaches in basketball to include moderate, but particularly high intensity exercise into their skills sessions. This specific training may enable players at all levels of the game to better cope with the demands of the game on court and maintain a higher standard of play

  20. Highly integrated image sensors enable low-cost imaging systems

    Science.gov (United States)

    Gallagher, Paul K.; Lake, Don; Chalmers, David; Hurwitz, J. E. D.

    1997-09-01

    The highest barriers to wide scale implementation of vision systems have been cost. This is closely followed by the level of difficulty of putting a complete imaging system together. As anyone who has every been in the position of creating a vision system knows, the various bits and pieces supplied by the many vendors are not under any type of standardization control. In short, unless you are an expert in imaging, electrical interfacing, computers, digital signal processing, and high speed storage techniques, you will likely spend more money trying to do it yourself rather than to buy the exceedingly expensive systems available. Another alternative is making headway into the imaging market however. The growing investment in highly integrated CMOS based imagers is addressing both the cost and the system integration difficulties. This paper discusses the benefits gained from CMOS based imaging, and how these benefits are already being applied.

  1. INTEGRAL highlights in the high energy astrophysics panorama

    Energy Technology Data Exchange (ETDEWEB)

    Ubertini, P.; Bazzano, A.

    2013-10-15

    ESAs INTEGRAL Space Observatory has spent his first decade in orbit, and its scientific outcome has completely changed our view of the hard-X/soft γ-ray sky. The scientific result comprises, among other discoveries, the production of the all-sky high energy sources catalogue, confirming the time variability over all time scales of most of the soft γ-ray sources observed, the first detailed map of the Aluminium and 511 keV annihilation line in the Galaxy and the evidence of polarized γ-ray emission from the Crab Nebula and Cyg X-1. This paper will review the latest INTEGRAL discoveries in the framework of the high energy sky panorama.

  2. Social Representations of the Integrated High School Students about Astronomy

    Science.gov (United States)

    Barbosa, Jose Isnaldo de Lima; Voelzke, Marcos Rincon

    2017-07-01

    Astronomy issues are not always adequately handled in the formal education system, as well as, their dissemination in the media is often loaded with sensationalism. However, in this context the students are forming their explanations about it. Therefore, this work has the objective of identifying the possible social representations of students from the Integrated High School on the inductor term Astronomy. It is basically a descriptive research, therefore, a quali-qualitative approach was adopted. The procedures for obtaining the data occurred in the form of a survey, and they involved 653 subjects students from the Integrated High School. The results indicate that the surveyed students have social representations of the object Astronomy, which are based on elements from the formal education space, and also disclosed in the media. In addition, they demonstrate that the students have information about Astronomy, and a value judgment in relation to this science.

  3. Integrated microcantilevers for high-resolution sensing and probing

    International Nuclear Information System (INIS)

    Li, Xinxin; Lee, Dong-Weon

    2012-01-01

    This topical review is focused on microcantilever-based sensing and probing functions that are realized by integrating a mechanically compliant cantilever with self-sensing and self-actuating elements, specific sensing materials as well as functionalized nano-tips. Such integrated cantilever devices have shown great promise in ultra-sensitive applications such as on-the-spot portable bio/chemical detection and in situ micro/nanoscale surface analysis and manipulation. The technical details of this review will be given in a sequence of cantilever sensors and, then, cantilever-tip probes. For the integrated cantilever sensors, the frequency-output style dynamic cantilevers are described first, with the contents including optimized resonance modes, sensing-group-modified nanostructures for specific bio/chemical mass adsorption and nanoscale sensing effects, etc. Thereafter, the static cantilever sensors for surface-stress detection are described in the sequence of the sensing mechanism, surface modification of the sensitive molecule layer and the model of specific reaction-induced surface-energy variation. After technical description of the cantilever sensors, the emphasis of the review moves to functionalized nano-tip equipped cantilever-tip probing devices. The probing functions are not only integrated on the cantilever but also integrated at the sharp apex of the tip. After description of single integrated cantilever probes and their applications in surface scanning and imaging, arrayed cantilever-tip devices and their simultaneous parallel operation for high throughput imaging and nanomechanical data storage are also addressed. With cantilever-tip probes as key elements, micro-analysis instruments are introduced that can be widely used for macro/nanoscale characterizations. (topical review)

  4. Application specific integrated circuit for high temperature oil well applications

    Energy Technology Data Exchange (ETDEWEB)

    Fallet, T.; Gakkestad, J.; Forre, G.

    1994-12-31

    This paper describes the design of an integrated BiCMOS circuit for high temperature applications. The circuit contains Pierce oscillators with automatic gain control, and measurements show that it is operating up to 266{sup o}C. The relative frequency variation up to 200 {sup o}C is less than 60 ppm caused mainly by the crystal element itself. 4 refs., 7 figs.

  5. High throughput integrated thermal characterization with non-contact optical calorimetry

    Science.gov (United States)

    Hou, Sichao; Huo, Ruiqing; Su, Ming

    2017-10-01

    Commonly used thermal analysis tools such as calorimeter and thermal conductivity meter are separated instruments and limited by low throughput, where only one sample is examined each time. This work reports an infrared based optical calorimetry with its theoretical foundation, which is able to provide an integrated solution to characterize thermal properties of materials with high throughput. By taking time domain temperature information of spatially distributed samples, this method allows a single device (infrared camera) to determine the thermal properties of both phase change systems (melting temperature and latent heat of fusion) and non-phase change systems (thermal conductivity and heat capacity). This method further allows these thermal properties of multiple samples to be determined rapidly, remotely, and simultaneously. In this proof-of-concept experiment, the thermal properties of a panel of 16 samples including melting temperatures, latent heats of fusion, heat capacities, and thermal conductivities have been determined in 2 min with high accuracy. Given the high thermal, spatial, and temporal resolutions of the advanced infrared camera, this method has the potential to revolutionize the thermal characterization of materials by providing an integrated solution with high throughput, high sensitivity, and short analysis time.

  6. High-accuracy determination of the neutron flux in the new experimental area nTOF-EAR2 at CERN

    Energy Technology Data Exchange (ETDEWEB)

    Sabate-Gilarte, M. [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Universidad de Sevilla, Departamento de Fisica Atomica, Molecular y Nuclear, Sevilla (Spain); Barbagallo, M.; Colonna, N.; Damone, L.; Belloni, F.; Mastromarco, M.; Tagliente, G.; Variale, V. [Istituto Nazionale di Fisica Nucleare, Sezione di Bari, Bari (Italy); Gunsing, F.; Berthoumieux, E.; Diakaki, M.; Papaevangelou, T.; Dupont, E. [Universite Paris-Saclay, CEA Irfu, Gif-sur-Yvette (France); Zugec, P.; Bosnar, D. [University of Zagreb, Department of Physics, Faculty of Science, Zagreb (Croatia); Vlachoudis, V.; Aberle, O.; Brugger, M.; Calviani, M.; Cardella, R.; Cerutti, F.; Chiaveri, E.; Ferrari, A.; Kadi, Y.; Losito, R.; Macina, D.; Montesano, S.; Rubbia, C. [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Chen, Y.H.; Audouin, L.; Tassan-Got, L. [Centre National de la Recherche Scientifique/IN2P3 - IPN, Orsay (France); Stamatopoulos, A.; Kokkoris, M.; Tsinganis, A.; Vlastou, R. [National Technical University of Athens (NTUA), Athens (Greece); Lerendegui-Marco, J.; Cortes-Giraldo, M.A.; Guerrero, C.; Quesada, J.M. [Universidad de Sevilla, Departamento de Fisica Atomica, Molecular y Nuclear, Sevilla (Spain); Villacorta, A. [University of Salamanca, Salamanca (Spain); Cosentino, L.; Finocchiaro, P.; Piscopo, M. [INFN, Laboratori Nazionali del Sud, Catania (Italy); Musumarra, A. [INFN, Laboratori Nazionali del Sud, Catania (Italy); Universita di Catania, Dipartimento di Fisica, Catania (Italy); Andrzejewski, J.; Gawlik, A.; Marganiec, J.; Perkowski, J. [University of Lodz, Lodz (Poland); Becares, V.; Balibrea, J.; Cano-Ott, D.; Garcia, A.R.; Gonzalez, E.; Martinez, T.; Mendoza, E. [Centro de Investigaciones Energeticas Medioambientales y Tecnologicas (CIEMAT), Madrid (Spain); Bacak, M.; Weiss, C. [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Technische Universitaet Wien, Wien (Austria); Baccomi, R.; Milazzo, P.M. [Istituto Nazionale di Fisica Nucleare, Sezione di Trieste, Trieste (Italy); Barros, S.; Ferreira, P.; Goncalves, I.F.; Vaz, P. [Instituto Superior Tecnico, Lisbon (Portugal); Becvar, F.; Krticka, M.; Valenta, S. [Charles University, Prague (Czech Republic); Beinrucker, C.; Goebel, K.; Heftrich, T.; Reifarth, R.; Schmidt, S.; Weigand, M.; Wolf, C. [Goethe University Frankfurt, Frankfurt (Germany); Billowes, J.; Frost, R.J.W.; Ryan, J.A.; Smith, A.G.; Warren, S.; Wright, T. [University of Manchester, Manchester (United Kingdom); Caamano, M.; Deo, K.; Duran, I.; Fernandez-Dominguez, B.; Leal-Cidoncha, E.; Paradela, C.; Robles, M.S. [University of Santiago de Compostela, Santiago de Compostela (Spain); Calvino, F.; Casanovas, A.; Riego-Perez, A. [Universitat Politecnica de Catalunya, Barcelona (Spain); Castelluccio, D.M.; Lo Meo, S. [Agenzia Nazionale per le Nuove Tecnologie (ENEA), Bologna (Italy); Istituto Nazionale di Fisica Nucleare, Sezione di Bologna, Bologna (Italy); Cortes, G.; Mengoni, A. [Agenzia Nazionale per le Nuove Tecnologie (ENEA), Bologna (Italy); Domingo-Pardo, C.; Tain, J.L. [Universidad de Valencia, Instituto de Fisica Corpuscular, Valencia (Spain); Dressler, R.; Heinitz, S.; Kivel, N.; Maugeri, E.A.; Schumann, D. [Paul Scherrer Institut (PSI), Villingen (Switzerland); Furman, V.; Sedyshev, P. [Joint Institute for Nuclear Research (JINR), Dubna (Russian Federation); Gheorghe, I.; Glodariu, T.; Mirea, M.; Oprea, A. [Horia Hulubei National Institute of Physics and Nuclear Engineering, Magurele (Romania); Goverdovski, A.; Ketlerov, V.; Khryachkov, V. [Institute of Physics and Power Engineering (IPPE), Obninsk (Russian Federation); Griesmayer, E.; Jericha, E.; Kavrigin, P.; Leeb, H. [Technische Universitaet Wien, Wien (Austria); Harada, H.; Kimura, A. [Japan Atomic Energy Agency (JAEA), Tokai-mura (Japan); Hernandez-Prieto, A. [European Organization for Nuclear Research (CERN), Geneva (CH); Universitat Politecnica de Catalunya, Barcelona (ES); Heyse, J.; Schillebeeckx, P. [European Commission, Joint Research Centre, Geel (BE); Jenkins, D.G. [University of York, York (GB); Kaeppeler, F. [Karlsruhe Institute of Technology, Karlsruhe (DE); Katabuchi, T. [Tokyo Institute of Technology, Tokyo (JP); Lederer, C.; Lonsdale, S.J.; Woods, P.J. [University of Edinburgh, School of Physics and Astronomy, Edinburgh (GB); Licata, M.; Massimi, C.; Vannini, G. [Istituto Nazionale di Fisica Nucleare, Sezione di Bologna, Bologna (IT); Universita di Bologna, Dipartimento di Fisica e Astronomia, Bologna (IT); Mastinu, P. [Istituto Nazionale di Fisica Nucleare, Sezione di Legnaro, Legnaro (IT); Matteucci, F. [Istituto Nazionale di Fisica Nucleare, Sezione di Trieste, Trieste (IT); Universita di Trieste, Dipartimento di Astronomia, Trieste (IT); Mingrone, F. [European Organization for Nuclear Research (CERN), Geneva (CH); Istituto Nazionale di Fisica Nucleare, Sezione di Bologna, Bologna (IT); Nolte, R. [Physikalisch-Technische Bundesanstalt (PTB), Braunschweig (DE); Palomo-Pinto, F.R. [Universidad de Sevilla, Dept. Ingenieria Electronica, Escuela Tecnica Superior de Ingenieros, Sevilla (ES); Patronis, N. [University of Ioannina, Ioannina (GR); Pavlik, A. [University of Vienna, Faculty of Physics, Vienna (AT); Porras, J.I. [University of Granada, Granada (ES); Praena, J. [Universidad de Sevilla, Departamento de Fisica Atomica, Molecular y Nuclear, Sevilla (ES); University of Granada, Granada (ES); Rajeev, K.; Rout, P.C.; Saxena, A.; Suryanarayana, S.V. [Bhabha Atomic Research Centre (BARC), Mumbai (IN); Rauscher, T. [University of Hertfordshire, Centre for Astrophysics Research, Hatfield (GB); University of Basel, Department of Physics, Basel (CH); Tarifeno-Saldivia, A. [Universitat Politecnica de Catalunya, Barcelona (ES); Universidad de Valencia, Instituto de Fisica Corpuscular, Valencia (ES); Ventura, A. [Istituto Nazionale di Fisica Nucleare, Sezione di Bologna, Bologna (IT); Wallner, A. [Australian National University, Canberra (AU)

    2017-10-15

    A new high flux experimental area has recently become operational at the nTOF facility at CERN. This new measuring station, nTOF-EAR2, is placed at the end of a vertical beam line at a distance of approximately 20 m from the spallation target. The characterization of the neutron beam, in terms of flux, spatial profile and resolution function, is of crucial importance for the feasibility study and data analysis of all measurements to be performed in the new area. In this paper, the measurement of the neutron flux, performed with different solid-state and gaseous detection systems, and using three neutron-converting reactions considered standard in different energy regions is reported. The results of the various measurements have been combined, yielding an evaluated neutron energy distribution in a wide energy range, from 2 meV to 100 MeV, with an accuracy ranging from 2%, at low energy, to 6% in the high-energy region. In addition, an absolute normalization of the nTOF-EAR2 neutron flux has been obtained by means of an activation measurement performed with {sup 197}Au foils in the beam. (orig.)

  7. Achieving High Reliability Operations Through Multi-Program Integration

    Energy Technology Data Exchange (ETDEWEB)

    Holly M. Ashley; Ronald K. Farris; Robert E. Richards

    2009-04-01

    Over the last 20 years the Idaho National Laboratory (INL) has adopted a number of operations and safety-related programs which has each periodically taken its turn in the limelight. As new programs have come along there has been natural competition for resources, focus and commitment. In the last few years, the INL has made real progress in integrating all these programs and are starting to realize important synergies. Contributing to this integration are both collaborative individuals and an emerging shared vision and goal of the INL fully maturing in its high reliability operations. This goal is so powerful because the concept of high reliability operations (and the resulting organizations) is a masterful amalgam and orchestrator of the best of all the participating programs (i.e. conduct of operations, behavior based safety, human performance, voluntary protection, quality assurance, and integrated safety management). This paper is a brief recounting of the lessons learned, thus far, at the INL in bringing previously competing programs into harmony under the goal (umbrella) of seeking to perform regularly as a high reliability organization. In addition to a brief diagram-illustrated historical review, the authors will share the INL’s primary successes (things already effectively stopped or started) and the gaps yet to be bridged.

  8. Integration study of high quality teaching resources in universities

    Directory of Open Access Journals (Sweden)

    Honglu Liu

    2012-12-01

    Full Text Available Purpose: The development level and quality of education depend on the merits and efficiency in the use of teaching resources, especially in the case of obvious contradiction between the demand and supply of teaching resources. So to integrate teaching resources, improve the efficiency in the use of high quality teaching resources, and take the road of content development to enhance the competitiveness of education has become very important and urgent.Design/methodology/approach: On the basis of analysis on the teaching resources of universities and the problems they faced, this paper introduced the basic concepts of cloud storage, and built the integration architecture of high quality teaching resources in universities based on the cloud storage.Findings and Originality/value: The HDFS-based cloud storage proposed in this paper is a dynamically adjustable and Internet-based storage solution, and the users can access storage targets using the network through a common and easy-to-use protocol and application programming interfaces. This new technology is useful for end users benefits. With the continuous development and improvement of cloud storage, it will necessarily result in more and more applications in the institutions of higher learning and education network.Originality/value: This paper introduced the cloud storage into the integration of high quality teaching resources in universities first and as a new form of service, it can be a good solution.

  9. EU Defence Industry Integration between Spillover and High Politics

    DEFF Research Database (Denmark)

    Kluth, Michael Friederich

    on an intergovernmental base. In the past 10 years, however, the defence industries of the major EU powers have instigated a move from cross national collaboration to cross national consolidation. Cross border mergers and acquisitions has been carried out and pressures for regulatory mainstreaming is mounting....... This raises the question: are we witnessing an incursion of spillover mechanisms into the ‘High Politics' domain of the defence industry? What are the drivers eroding the ‘High Politics' character of defence industry integration? Are market forces at play? Does it reflect pressures for institutional...

  10. Performance of digital integrated circuit technologies at very high temperatures

    Energy Technology Data Exchange (ETDEWEB)

    Prince, J.L.; Draper, B.L.; Rapp, E.A.; Kromberg, J.N.; Fitch, L.T.

    1980-01-01

    Results of investigations of the performance and reliability of digital bipolar and CMOS integrated circuits over the 25 to 340/sup 0/C range are reported. Included in these results are both parametric variation information and analysis of the functional failure mechanisms. Although most of the work was done using commercially available circuits (TTL and CMOS) and test chips from commercially compatible processes, some results of experimental simulations of dielectrically isolated CMOS are also discussed. It was found that commercial Schottky clamped TTL, and dielectrically isolated, low power Schottky-clamped TTL, functioned to junction temperatures in excess of 325/sup 0/C. Standard gold doped TTL functioned only to 250/sup 0/C, while commercial, isolated I/sup 2/L functioned to the range 250/sup 0/C to 275/sup 0/C. Commercial junction isolated CMOS, buffered and unbuffered, functioned to the range 280/sup 0/C to 310/sup 0/C/sup +/, depending on the manufacturer. Experimental simulations of simple dielectrically isolated CMOS integrated circuits, fabricated with heavier doping levels than normal, functioned to temperatures in excess of 340/sup 0/C. High temperature life testing of experimental, silicone-encapsulated simple TTL and CMOS integrated circuits have shown no obvious life limiting problems to date. No barrier to reliable functionality of TTL bipolar or CMOS integrated ciruits at temperatures in excess of 300/sup 0/C has been found.

  11. Integrated High Resolution Digital Color Light Sensor in 130 nm CMOS Technology

    Directory of Open Access Journals (Sweden)

    Drago Strle

    2015-07-01

    Full Text Available This article presents a color light detection system integrated in 130 nm CMOS technology. The sensors and corresponding electronics detect light in a CIE XYZ color luminosity space using on-chip integrated sensors without any additional process steps, high-resolution analog-to-digital converter, and dedicated DSP algorithm. The sensor consists of a set of laterally arranged integrated photodiodes that are partly covered by metal, where color separation between the photodiodes is achieved by lateral carrier diffusion together with wavelength-dependent absorption. A high resolution, hybrid, ∑∆ ADC converts each photo diode’s current into a 22-bit digital result, canceling the dark current of the photo diodes. The digital results are further processed by the DSP, which calculates normalized XYZ or RGB color and intensity parameters using linear transformations of the three photo diode responses by multiplication of the data with a transformation matrix, where the coefficients are extracted by training in combination with a pseudo-inverse operation and the least-mean square approximation. The sensor system detects the color light parameters with 22-bit accuracy, consumes less than 60 μA on average at 10 readings per second, and occupies approx. 0.8 mm2 of silicon area (including three photodiodes and the analog part of the ADC. The DSP is currently implemented on FPGA.

  12. Integrated High Resolution Digital Color Light Sensor in 130 nm CMOS Technology.

    Science.gov (United States)

    Strle, Drago; Nahtigal, Uroš; Batistell, Graciele; Zhang, Vincent Chi; Ofner, Erwin; Fant, Andrea; Sturm, Johannes

    2015-07-22

    This article presents a color light detection system integrated in 130 nm CMOS technology. The sensors and corresponding electronics detect light in a CIE XYZ color luminosity space using on-chip integrated sensors without any additional process steps, high-resolution analog-to-digital converter, and dedicated DSP algorithm. The sensor consists of a set of laterally arranged integrated photodiodes that are partly covered by metal, where color separation between the photodiodes is achieved by lateral carrier diffusion together with wavelength-dependent absorption. A high resolution, hybrid, ∑∆ ADC converts each photo diode's current into a 22-bit digital result, canceling the dark current of the photo diodes. The digital results are further processed by the DSP, which calculates normalized XYZ or RGB color and intensity parameters using linear transformations of the three photo diode responses by multiplication of the data with a transformation matrix, where the coefficients are extracted by training in combination with a pseudo-inverse operation and the least-mean square approximation. The sensor system detects the color light parameters with 22-bit accuracy, consumes less than 60 μA on average at 10 readings per second, and occupies approx. 0.8 mm(2) of silicon area (including three photodiodes and the analog part of the ADC). The DSP is currently implemented on FPGA.

  13. Low power and high accuracy spike sorting microprocessor with on-line interpolation and re-alignment in 90 nm CMOS process.

    Science.gov (United States)

    Chen, Tung-Chien; Ma, Tsung-Chuan; Chen, Yun-Yu; Chen, Liang-Gee

    2012-01-01

    Accurate spike sorting is an important issue for neuroscientific and neuroprosthetic applications. The sorting of spikes depends on the features extracted from the neural waveforms, and a better sorting performance usually comes with a higher sampling rate (SR). However for the long duration experiments on free-moving subjects, the miniaturized and wireless neural recording ICs are the current trend, and the compromise on sorting accuracy is usually made by a lower SR for the lower power consumption. In this paper, we implement an on-chip spike sorting processor with integrated interpolation hardware in order to improve the performance in terms of power versus accuracy. According to the fabrication results in 90nm process, if the interpolation is appropriately performed during the spike sorting, the system operated at the SR of 12.5 k samples per second (sps) can outperform the one not having interpolation at 25 ksps on both accuracy and power.

  14. Enhancement of high density polyethylene high integrity containers at a low level radioactive waste disposal site

    International Nuclear Information System (INIS)

    Sauer, R.E.; Wong, O.P.

    1989-01-01

    High integrity containers (HIC) made of high density polyethylene (HDPE) have been used for disposal in South Carolina since the late seventies. With the recent definitive position taken by the NRC on the suitability of these containers for disposal, alternative means of assuring the structural integrity of the containers for the long term became necessary. The authors' company has developed an utilized reinforced concrete caissons at the Hanford, Washington site as an additional barrier and structural element to assure the long term high integrity function of the current HDPE HIC's also known as Poly HIC's on the market. This paper outlines the background of the HIC's in question, the NRC positions and ruling, and presents technical bases for the applicability of appropriately designed concrete overpacks to augment the structural integrity of HIC's

  15. Diagnostic accuracy of an integrated respiratory guideline in identifying patients with respiratory symptoms requiring screening for pulmonary tuberculosis: a cross-sectional study

    Directory of Open Access Journals (Sweden)

    Majara Bosielo P

    2006-08-01

    Full Text Available Abstract Background To evaluate the diagnostic accuracy of the integrated Practical Approach to Lung Health in South Africa (PALSA guideline in identifying patients requiring bacteriological screening for tuberculosis (TB, and to determine which clinical features best predict suspected and bacteriologically-confirmed tuberculosis among patients with respiratory symptoms. Methods A prospective, cross-sectional study in which 1392 adult patients with cough and/or difficult breathing, attending a primary care facility in Cape Town, South Africa, were evaluated by a nurse using the guideline. The accuracy of a nurse using the guideline to identify TB suspects was compared to that of primary care physicians' diagnoses of (1 suspected TB, and (2 proven TB supported by clinical information and chest radiographs. Results The nurse using the guideline identified 516 patients as TB suspects compared with 365 by the primary care physicians, representing a sensitivity of 76% (95% confidence interval (CI 71%–79%, specificity of 77% (95% CI 74%–79%, positive predictive value of 53% (95% CI 49%–58%, negative predictive value of 90% (95% CI 88%–92%, and area under the receiver operating characteristic curve (ARUC of 0.76 (95% CI 0.74–0.79. Sputum results were obtained in 320 of the 365 primary care physicians TB suspects (88%; 40 (13% of these were positive for TB. Only 4 cases were not identified by the nurse using the guideline. The primary care physicians diagnostic accuracy in diagnosing bacteriologically-confirmed TB (n = 320 was as follows: sensitivity 90% (95% CI 76%–97%, specificity 65% (95% CI 63%–68%, negative predictive value 7% (95% CI 5%–10%, positive predictive value 99.5% (95% CI 98.8%–99.8%, and ARUC 0.78 (95% CI 0.73–0.82. Weight loss, pleuritic pain, and night sweats were independently associated with the diagnosis of bacteriologically-confirmed tuberculosis (positive likelihood ratio if all three present = 16.7, 95% CI 5

  16. Integrated safeguards and security for a highly automated process

    International Nuclear Information System (INIS)

    Zack, N.R.; Hunteman, W.J.; Jaeger, C.D.

    1993-01-01

    Before the cancellation of the New Production Reactor Programs for the production of tritium, the reactors and associated processing were being designed to contain some of the most highly automated and remote systems conceived for a Department of Energy facility. Integrating safety, security, materials control and accountability (MC and A), and process systems at the proposed facilities would enhance the overall information and protection-in-depth available. Remote, automated fuel handling and assembly/disassembly techniques would deny access to the nuclear materials while upholding ALARA principles but would also require the full integration of all data/information systems. Such systems would greatly enhance MC and A as well as facilitate materials tracking. Physical protection systems would be connected with materials control features to cross check activities and help detect and resolve anomalies. This paper will discuss the results of a study of the safeguards and security benefits achieved from a highly automated and integrated remote nuclear facility and the impacts that such systems have on safeguards and computer and information security

  17. A High-Temperature Piezoresistive Pressure Sensor with an Integrated Signal-Conditioning Circuit

    Directory of Open Access Journals (Sweden)

    Zong Yao

    2016-06-01

    Full Text Available This paper focuses on the design and fabrication of a high-temperature piezoresistive pressure sensor with an integrated signal-conditioning circuit, which consists of an encapsulated pressure-sensitive chip, a temperature compensation circuit and a signal-conditioning circuit. A silicon on insulation (SOI material and a standard MEMS process are used in the pressure-sensitive chip fabrication, and high-temperature electronic components are adopted in the temperature-compensation and signal-conditioning circuits. The entire pressure sensor achieves a hermetic seal and can be operated long-term in the range of −50 °C to 220 °C. Unlike traditional pressure sensor output voltage ranges (in the dozens to hundreds of millivolts, the output voltage of this sensor is from 0 V to 5 V, which can significantly improve the signal-to-noise ratio and measurement accuracy in practical applications of long-term transmission based on experimental verification. Furthermore, because this flexible sensor’s output voltage is adjustable, general follow-up pressure transmitter devices for voltage converters need not be used, which greatly reduces the cost of the test system. Thus, the proposed high-temperature piezoresistive pressure sensor with an integrated signal-conditioning circuit is expected to be highly applicable to pressure measurements in harsh environments.

  18. High Accuracy Potential Energy Surface, Dipole Moment Surface, Rovibrational Energies and Line List Calculations for ^{14}NH_3

    Science.gov (United States)

    Coles, Phillip; Yurchenko, Sergei N.; Polyansky, Oleg; Kyuberis, Aleksandra; Ovsyannikov, Roman I.; Zobov, Nikolay Fedorovich; Tennyson, Jonathan

    2017-06-01

    We present a new spectroscopic potential energy surface (PES) for ^{14}NH_3, produced by refining a high accuracy ab initio PES to experimental energy levels taken predominantly from MARVEL. The PES reproduces 1722 matched J=0-8 experimental energies with a root-mean-square error of 0.035 cm-1 under 6000 cm^{-1} and 0.059 under 7200 cm^{-1}. In conjunction with a new DMS calculated using multi reference configuration interaction (MRCI) and H=aug-cc-pVQZ, N=aug-cc-pWCVQZ basis sets, an infrared (IR) line list has been computed which is suitable for use up to 2000 K. The line list is used to assign experimental lines in the 7500 - 10,500 cm^{-1} region and previously unassigned lines in HITRAN in the 6000-7000 cm^{-1} region. Oleg L. Polyansky, Roman I. Ovsyannikov, Aleksandra A. Kyuberis, Lorenzo Lodi, Jonathan Tennyson, Andrey Yachmenev, Sergei N. Yurchenko, Nikolai F. Zobov, J. Mol. Spec., 327 (2016) 21-30 Afaf R. Al Derzia, Tibor Furtenbacher, Jonathan Tennyson, Sergei N. Yurchenko, Attila G. Császár, J. Quant. Spectrosc. Rad. Trans., 161 (2015) 117-130

  19. Emergence of realism: Enhanced visual artistry and high accuracy of visual numerosity representation after left prefrontal damage.

    Science.gov (United States)

    Takahata, Keisuke; Saito, Fumie; Muramatsu, Taro; Yamada, Makiko; Shirahase, Joichiro; Tabuchi, Hajime; Suhara, Tetsuya; Mimura, Masaru; Kato, Motoichiro

    2014-05-01

    Over the last two decades, evidence of enhancement of drawing and painting skills due to focal prefrontal damage has accumulated. It is of special interest that most artworks created by such patients were highly realistic ones, but the mechanism underlying this phenomenon remains to be understood. Our hypothesis is that enhanced tendency of realism was associated with accuracy of visual numerosity representation, which has been shown to be mediated predominantly by right parietal functions. Here, we report a case of left prefrontal stroke, where the patient showed enhancement of artistic skills of realistic painting after the onset of brain damage. We investigated cognitive, functional and esthetic characteristics of the patient׳s visual artistry and visual numerosity representation. Neuropsychological tests revealed impaired executive function after the stroke. Despite that, the patient׳s visual artistry related to realism was rather promoted across the onset of brain damage as demonstrated by blind evaluation of the paintings by professional art reviewers. On visual numerical cognition tasks, the patient showed higher performance in comparison with age-matched healthy controls. These results paralleled increased perfusion in the right parietal cortex including the precuneus and intraparietal sulcus. Our data provide new insight into mechanisms underlying change in artistic style due to focal prefrontal lesion. Copyright © 2014 Elsevier Ltd. All rights reserved.

  20. High-accuracy measurements of snow Bidirectional Reflectance Distribution Function at visible and NIR wavelengths – comparison with modelling results

    Directory of Open Access Journals (Sweden)

    M. Dumont

    2010-03-01

    Full Text Available High-accuracy measurements of snow Bidirectional Reflectance Distribution Function (BRDF were performed for four natural snow samples with a spectrogonio-radiometer in the 500–2600 nm wavelength range. These measurements are one of the first sets of direct snow BRDF values over a wide range of lighting and viewing geometry. They were compared to BRDF calculated with two optical models. Variations of the snow anisotropy factor with lighting geometry, wavelength and snow physical properties were investigated. Results show that at wavelengths with small penetration depth, scattering mainly occurs in the very top layers and the anisotropy factor is controlled by the phase function. In this condition, forward scattering peak or double scattering peak is observed. In contrast at shorter wavelengths, the penetration of the radiation is much deeper and the number of scattering events increases. The anisotropy factor is thus nearly constant and decreases at grazing observation angles. The whole dataset is available on demand from the corresponding author.

  1. Preliminary Guideline for the High Temperature Structure Integrity Assessment Procedure Part II. High Temperature Structural Integrity Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jae Han; Kim, J. B.; Lee, H. Y.; Park, C. G.; Joo, Y. S.; Koo, G. H.; Kim, S. H

    2007-02-15

    A high temperature structural integrity assessment belongs to the Part II of a whole preliminary guideline for the high temperature structure. The main contents of this guideline are the evaluation procedures of the creep-fatigue crack initiation and growth in high temperature condition, the high temperature LBB evaluation procedure, and the inelastic evaluations of the welded joints in SFR structures. The methodologies for the proper inelastic analysis of an SFR structures in high temperatures are explained and the guidelines of inelastic analysis options using ANSYS and ABAQUS are suggested. In addition, user guidelines for the developed NONSTA code are included. This guidelines need to be continuously revised to improve the applicability to the design and analysis of the SFR structures.

  2. High sensitive quench detection method using an integrated test wire

    International Nuclear Information System (INIS)

    Fevrier, A.; Tavergnier, J.P.; Nithart, H.; Kiblaire, M.; Duchateau, J.L.

    1981-01-01

    A high sensitive quench detection method which works even in the presence of an external perturbing magnetic field is reported. The quench signal is obtained from the difference in voltages at the superconducting winding terminals and at the terminals at a secondary winding strongly coupled to the primary. The secondary winding could consist of a ''zero-current strand'' of the superconducting cable not connected to one of the winding terminals or an integrated normal test wire inside the superconducting cable. Experimental results on quench detection obtained by this method are described. It is shown that the integrated test wire method leads to efficient and sensitive quench detection, especially in the presence of an external perturbing magnetic field

  3. High-density amorphous ice: A path-integral simulation

    Science.gov (United States)

    Herrero, Carlos P.; Ramírez, Rafael

    2012-09-01

    Structural and thermodynamic properties of high-density amorphous (HDA) ice have been studied by path-integral molecular dynamics simulations in the isothermal-isobaric ensemble. Interatomic interactions were modeled by using the effective q-TIP4P/F potential for flexible water. Quantum nuclear motion is found to affect several observable properties of the amorphous solid. At low temperature (T = 50 K) the molar volume of HDA ice is found to increase by 6%, and the intramolecular O-H distance rises by 1.4% due to quantum motion. Peaks in the radial distribution function of HDA ice are broadened with respect to their classical expectancy. The bulk modulus, B, is found to rise linearly with the pressure, with a slope ∂B/∂P = 7.1. Our results are compared with those derived earlier from classical and path-integral simulations of HDA ice. We discuss similarities and discrepancies with those earlier simulations.

  4. Determining the Accuracy of Paleomagnetic Remanence and High-Resolution Chronostratigraphy for Sedimentary Rocks using Rock Magnetics

    Science.gov (United States)

    Kodama, K. P.

    2017-12-01

    The talk will consider two broad topics in rock magnetism and paleomagnetism: the accuracy of paleomagnetic remanence and the use of rock magnetics to measure geologic time in sedimentary sequences. The accuracy of the inclination recorded by sedimentary rocks is crucial to paleogeographic reconstructions. Laboratory compaction experiments show that inclination shallows on the order of 10˚-15˚. Corrections to the inclination can be made using the effects of compaction on the directional distribution of secular variation recorded by sediments or the anisotropy of the magnetic grains carrying the ancient remanence. A summary of all the compaction correction studies as of 2012 shows that 85% of sedimentary rocks studied have enjoyed some amount of inclination shallowing. Future work should also consider the effect of grain-scale strain on paleomagnetic remanence. High resolution chronostratigraphy can be assigned to a sedimentary sequence using rock magnetics to detect astronomically-forced climate cycles. The power of the technique is relatively quick, non-destructive measurements, the objective identification of the cycles compared to facies interpretations, and the sensitivity of rock magnetics to subtle changes in sedimentary source. An example of this technique comes from using rock magnetics to identify astronomically-forced climate cycles in three globally distributed occurrences of the Shuram carbon isotope excursion. The Shuram excursion may record the oxidation of the world ocean in the Ediacaran, just before the Cambrian explosion of metazoans. Using rock magnetic cyclostratigraphy, the excursion is shown to have the same duration (8-9 Myr) in southern California, south China and south Australia. Magnetostratigraphy of the rocks carrying the excursion in California and Australia shows a reversed to normal geomagnetic field polarity transition at the excursion's nadir, thus supporting the synchroneity of the excursion globally. Both results point to a

  5. Linear Discriminant Analysis achieves high classification accuracy for the BOLD fMRI response to naturalistic movie stimuli.

    Directory of Open Access Journals (Sweden)

    Hendrik eMandelkow

    2016-03-01

    Full Text Available Naturalistic stimuli like movies evoke complex perceptual processes, which are of great interest in the study of human cognition by functional MRI (fMRI. However, conventional fMRI analysis based on statistical parametric mapping (SPM and the general linear model (GLM is hampered by a lack of accurate parametric models of the BOLD response to complex stimuli. In this situation, statistical machine-learning methods, a.k.a. multivariate pattern analysis (MVPA, have received growing attention for their ability to generate stimulus response models in a data-driven fashion. However, machine-learning methods typically require large amounts of training data as well as computational resources. In the past this has largely limited their application to fMRI experiments involving small sets of stimulus categories and small regions of interest in the brain. By contrast, the present study compares several classification algorithms known as Nearest Neighbour (NN, Gaussian Naïve Bayes (GNB, and (regularised Linear Discriminant Analysis (LDA in terms of their classification accuracy in discriminating the global fMRI response patterns evoked by a large number of naturalistic visual stimuli presented as a movie.Results show that LDA regularised by principal component analysis (PCA achieved high classification accuracies, above 90% on average for single fMRI volumes acquired 2s apart during a 300s movie (chance level 0.7% = 2s/300s. The largest source of classification errors were autocorrelations in the BOLD signal compounded by the similarity of consecutive stimuli. All classifiers performed best when given input features from a large region of interest comprising around 25% of the voxels that responded significantly to the visual stimulus. Consistent with this, the most informative principal components represented widespread distributions of co-activated brain regions that were similar between subjects and may represent functional networks. In light of these

  6. High-authority smart material integrated electric actuator

    Science.gov (United States)

    Weisensel, G. N.; Pierce, Thomas D.; Zunkel, Gary

    1997-05-01

    For many current applications, hydraulic power is still the preferred method of gaining mechanical advantage. However, in many of these applications, this power comes with the penalties of high weight, size, cost, and maintenance due to the system's distributed nature and redundancy requirements. A high authority smart material Integrated Electric Actuator (IEA) is a modular, self-contained linear motion device that is capable of producing dynamic output strokes similar to those of hydraulic actuators yet at significantly reduced weight and volume. It provides system simplification and miniaturization. This actuator concept has many innovative features, including a TERFENOL-D-based pump, TERFENOL-D- based active valves, control algorithms, a displacement amplification unit and integrated, unitized packaging. The IEA needs only electrical power and a control command signal as inputs to provide high authority, high response rate actuation. This approach is directly compatible with distributed control strategies. Aircraft control, automotive brakes and fuel injection, and fluid power delivery are just some examples of the IEA's pervasive applications in aerospace, defense and commercial systems.

  7. Fracture toughness evaluation of elastic-plastic J-integral for high temperature components of gas turbine in power plants

    International Nuclear Information System (INIS)

    Chung, Nam Yong; Kim, Moon Young; Kim, Jong Woo

    1999-01-01

    In the study, the analysis of elastic-plastic J-integral was performed in high temperature components for gas turbine based on elastic-plastic fracture mechanics. It had been operated on the range of about 700 deg C and degraded by high temperature. It was tested for material properties of used component because of material properties changing at high temperature condition. The elastic-plastic fracture mechanics parameter, J is obtained with finite element method. A method is suggested which determines J Ic applying analysis of elastic-plastic finite element method and results of experimental load-displacements with CT specimen. It is also investigated that J-integral is applied for the elastic-plastic analysis in high temperature components. The elastic-plastic fracture toughness. J Ic determined by finite element was obtained with high accuracy using the experimental method.=20

  8. Diagnostic accuracy of cone-beam computed tomography scans with high- and low-resolution modes for the detection of root perforations.

    Science.gov (United States)

    Shokri, Abbas; Eskandarloo, Amir; Norouzi, Marouf; Poorolajal, Jalal; Majidi, Gelareh; Aliyaly, Alireza

    2018-03-01

    This study compared the diagnostic accuracy of cone-beam computed tomography (CBCT) scans obtained with 2 CBCT systems with high- and low-resolution modes for the detection of root perforations in endodontically treated mandibular molars. The root canals of 72 mandibular molars were cleaned and shaped. Perforations measuring 0.2, 0.3, and 0.4 mm in diameter were created at the furcation area of 48 roots, simulating strip perforations, or on the external surfaces of 48 roots, simulating root perforations. Forty-eight roots remained intact (control group). The roots were filled using gutta-percha (Gapadent, Tianjin, China) and AH26 sealer (Dentsply Maillefer, Ballaigues, Switzerland). The CBCT scans were obtained using the NewTom 3G (QR srl, Verona, Italy) and Cranex 3D (Soredex, Helsinki, Finland) CBCT systems in high- and low-resolution modes, and were evaluated by 2 observers. The chi-square test was used to assess the nominal variables. In strip perforations, the accuracies of low- and high-resolution modes were 75% and 83% for NewTom 3G and 67% and 69% for Cranex 3D. In root perforations, the accuracies of low- and high-resolution modes were 79% and 83% for NewTom 3G and was 56% and 73% for Cranex 3D. The accuracy of the 2 CBCT systems was different for the detection of strip and root perforations. The Cranex 3D had non-significantly higher accuracy than the NewTom 3G. In both scanners, the high-resolution mode yielded significantly higher accuracy than the low-resolution mode. The diagnostic accuracy of CBCT scans was not affected by the perforation diameter.

  9. High-Voltage LED Light Engine with Integrated Driver

    Energy Technology Data Exchange (ETDEWEB)

    Soer, Wouter [Lumileds LLC, San Jose, CA (United States)

    2016-02-29

    LED luminaires have seen dramatic changes in cost breakdown over the past few years. The LED component cost, which until recently was the dominant portion of luminaire cost, has fallen to a level of the same order as the other luminaire components, such as the driver, housing, optics etc. With the current state of the technology, further luminaire performance improvement and cost reduction is realized most effectively by optimization of the whole system, rather than a single component. This project focuses on improving the integration between LEDs and drivers. Lumileds has developed a light engine platform based on low-cost high-power LEDs and driver topologies optimized for integration with these LEDs on a single substrate. The integration of driver and LEDs enables an estimated luminaire cost reduction of about 25% for targeted applications, mostly due to significant reductions in driver and housing cost. The high-power LEDs are based on Lumileds’ patterned sapphire substrate flip-chip (PSS-FC) technology, affording reduced die fabrication and packaging cost compared to existing technology. Two general versions of PSS-FC die were developed in order to create the desired voltage and flux increments for driver integration: (i) small single-junction die (0.5 mm2), optimal for distributed lighting applications, and (ii) larger multi-junction die (2 mm2 and 4 mm2) for high-power directional applications. Two driver topologies were developed: a tapped linear driver topology and a single-stage switch-mode topology, taking advantage of the flexible voltage configurations of the new PSS-FC die and the simplification opportunities enabled by integration of LEDs and driver on the same board. A prototype light engine was developed for an outdoor “core module” application based on the multi-junction PSS-FC die and the single-stage switch-mode driver. The light engine meets the project efficacy target of 128 lm/W at a luminous flux

  10. Xpert MTB/RIF testing in a low tuberculosis incidence, high-resource setting: limitations in accuracy and clinical impact.

    Science.gov (United States)

    Sohn, Hojoon; Aero, Abebech D; Menzies, Dick; Behr, Marcel; Schwartzman, Kevin; Alvarez, Gonzalo G; Dan, Andrei; McIntosh, Fiona; Pai, Madhukar; Denkinger, Claudia M

    2014-04-01

    Xpert MTB/RIF, the first automated molecular test for tuberculosis, is transforming the diagnostic landscape in low-income countries. However, little information is available on its performance in low-incidence, high-resource countries. We evaluated the accuracy of Xpert in a university hospital tuberculosis clinic in Montreal, Canada, for the detection of pulmonary tuberculosis on induced sputum samples, using mycobacterial cultures as the reference standard. We also assessed the potential reduction in time to diagnosis and treatment initiation. We enrolled 502 consecutive patients who presented for evaluation of possible active tuberculosis (most with abnormal chest radiographs, only 18% symptomatic). Twenty-five subjects were identified to have active tuberculosis by culture. Xpert had a sensitivity of 46% (95% confidence interval [CI], 26%-67%) and specificity of 100% (95% CI, 99%-100%) for detection of Mycobacterium tuberculosis. Sensitivity was 86% (95% CI, 42%-100%) in the 7 subjects with smear-positive results, and 28% (95% CI, 10%-56%) in the remaining subjects with smear-negative, culture-positive results; in this latter group, positive Xpert results were obtained a median 12 days before culture results. Subjects with positive cultures but negative Xpert results had minimal disease: 11 of 13 had no symptoms on presentation, and mean time to positive liquid culture results was 28 days (95% CI, 25-47 days) compared with 14 days (95% CI, 8-21 days) in Xpert/culture-positive cases. Our findings suggest limited potential impact of Xpert testing in high-resource, low-incidence ambulatory settings due to lower sensitivity in the context of less extensive disease, and limited potential to expedite diagnosis beyond what is achieved with the existing, well-performing diagnostic algorithm.

  11. A simple differential steady-state method to measure the thermal conductivity of solid bulk materials with high accuracy.

    Science.gov (United States)

    Kraemer, D; Chen, G

    2014-02-01

    Accurate measurements of thermal conductivity are of great importance for materials research and development. Steady-state methods determine thermal conductivity directly from the proportionality between heat flow and an applied temperature difference (Fourier Law). Although theoretically simple, in practice, achieving high accuracies with steady-state methods is challenging and requires rather complex experimental setups due to temperature sensor uncertainties and parasitic heat loss. We developed a simple differential steady-state method in which the sample is mounted between an electric heater and a temperature-controlled heat sink. Our method calibrates for parasitic heat losses from the electric heater during the measurement by maintaining a constant heater temperature close to the environmental temperature while varying the heat sink temperature. This enables a large signal-to-noise ratio which permits accurate measurements of samples with small thermal conductance values without an additional heater calibration measurement or sophisticated heater guards to eliminate parasitic heater losses. Additionally, the differential nature of the method largely eliminates the uncertainties of the temperature sensors, permitting measurements with small temperature differences, which is advantageous for samples with high thermal conductance values and/or with strongly temperature-dependent thermal conductivities. In order to accelerate measurements of more than one sample, the proposed method allows for measuring several samples consecutively at each temperature measurement point without adding significant error. We demonstrate the method by performing thermal conductivity measurements on commercial bulk thermoelectric Bi2Te3 samples in the temperature range of 30-150 °C with an error below 3%.

  12. A graphene integrated highly transparent resistive switching memory device

    Science.gov (United States)

    Dugu, Sita; Pavunny, Shojan P.; Limbu, Tej B.; Weiner, Brad R.; Morell, Gerardo; Katiyar, Ram S.

    2018-05-01

    We demonstrate the hybrid fabrication process of a graphene integrated highly transparent resistive random-access memory (TRRAM) device. The indium tin oxide (ITO)/Al2O3/graphene nonvolatile memory device possesses a high transmittance of >82% in the visible region (370-700 nm) and exhibits stable and non-symmetrical bipolar switching characteristics with considerably low set and reset voltages (ITO/Al2O3/Pt device and studied its switching characteristics for comparison and a better understanding of the ITO/Al2O3/graphene device characteristics. The conduction mechanisms in high and low resistance states were analyzed, and the observed polarity dependent resistive switching is explained based on electro-migration of oxygen ions.

  13. Accuracy of two root canal length measurement devices integrated into rotary endodontic motors when removing gutta-percha from root-filled teeth.

    Science.gov (United States)

    Uzun, O; Topuz, O; Tinaz, C; Nekoofar, M H; Dummer, P M H

    2008-09-01

    To evaluate ex vivo the accuracy of the integrated electronic root canal length measurement devices within TCM Endo V and Tri Auto ZX motors whilst removing gutta-percha and sealer from filled root canals. Forty freshly extracted maxillary and mandibular incisor teeth with mature apices were selected. Following access cavity preparation, the length of the root canals were measured visually 0.5 mm short of the major foramen (TL). The canals were prepared using the HERO 642 system and then filled with gutta-percha and AH26 sealer using a lateral compaction technique. After 7 days the coronal temporary filling was removed and the roots mounted in an alginate experimental model. The roots were then randomly divided in two groups. The access cavities were filled with chloroform to soften the gutta-percha and allow its penetration using the Tri Auto ZX and the TCM Endo V devices in groups 1 and 2, respectively. The 'automatic apical reverse function' (ARL) of both devices was set to start at the 0.5 setting and the rotary instrument inserted inside the root canal until a beeping sound was heard and the rotation of the file stopped automatically. Once the auto reverse function had been initiated, the foot pedal of the motor was inactivated and the rubber stop placed against the reference point. The distance between the file tip and rubber stop was measured using a digital calliper to 0.01 mm accuracy (ARL). Then, a size 20, 0.02 taper instrument was attached to each device and inserted into the root canals without rotary motion until the integrated ERCLMDs positioned the instrument tips at the 0.5 setting as suggested by the devices. This length was again measured using a digital calliper (EL). The Mann-Whitney U-test was used to investigate statistical differences between the true canal length and those indicated by the two devices when used in 'automatic ARL and when inserted passively (EL). In the presence of gutta-percha, sealer and chloroform, the auto

  14. MULTI-SCALE SEGMENTATION OF HIGH RESOLUTION REMOTE SENSING IMAGES BY INTEGRATING MULTIPLE FEATURES

    Directory of Open Access Journals (Sweden)

    Y. Di

    2017-05-01

    Full Text Available Most of multi-scale segmentation algorithms are not aiming at high resolution remote sensing images and have difficulty to communicate and use layers’ information. In view of them, we proposes a method of multi-scale segmentation of high resolution remote sensing images by integrating multiple features. First, Canny operator is used to extract edge information, and then band weighted distance function is built to obtain the edge weight. According to the criterion, the initial segmentation objects of color images can be gained by Kruskal minimum spanning tree algorithm. Finally segmentation images are got by the adaptive rule of Mumford–Shah region merging combination with spectral and texture information. The proposed method is evaluated precisely using analog images and ZY-3 satellite images through quantitative and qualitative analysis. The experimental results show that the multi-scale segmentation of high resolution remote sensing images by integrating multiple features outperformed the software eCognition fractal network evolution algorithm (highest-resolution network evolution that FNEA on the accuracy and slightly inferior to FNEA on the efficiency.

  15. An integral model of plume rise from high explosive detonations

    International Nuclear Information System (INIS)

    Boughton, B.A.; De Laurentis, J.M.

    1987-01-01

    A numerical model has been developed which provides a complete description of the time evolution of both the physical and thermodynamic properties of the cloud formed when a high explosive is detonated. This simulation employs the integral technique. The model equations are derived by integrating the three-dimensional conservation equations of mass, momentum and energy over the plume cross section. Assumptions are made regarding (a) plume symmetry; (b) the shape of profiles of velocity, temperature, etc. across the plume; and (c) the methodology for simulating entrainment and the effects of the crossflow induced pressure drag force on the plume. With these assumptions, the integral equations can be reduced to a set of ordinary differential equations on the plume centerline variables. Only the macroscopic plume characteristics, e.g., plume radius, centerline height, temperature and density, are predicted; details of the plume intrastructure are ignored. The model explicitly takes into account existing meteorology and has been expanded to consider the alterations in plume behavior which occur when aqueous foam is used as a dispersal mitigating material. The simulation was tested by comparison with field measurements of cloud top height and diameter. Predictions were within 25% of field observations over a wide range of explosive yield and atmospheric stability

  16. AFC-Enabled Simplified High-Lift System Integration Study

    Science.gov (United States)

    Hartwich, Peter M.; Dickey, Eric D.; Sclafani, Anthony J.; Camacho, Peter; Gonzales, Antonio B.; Lawson, Edward L.; Mairs, Ron Y.; Shmilovich, Arvin

    2014-01-01

    The primary objective of this trade study report is to explore the potential of using Active Flow Control (AFC) for achieving lighter and mechanically simpler high-lift systems for transonic commercial transport aircraft. This assessment was conducted in four steps. First, based on the Common Research Model (CRM) outer mold line (OML) definition, two high-lift concepts were developed. One concept, representative of current production-type commercial transonic transports, features leading edge slats and slotted trailing edge flaps with Fowler motion. The other CRM-based design relies on drooped leading edges and simply hinged trailing edge flaps for high-lift generation. The relative high-lift performance of these two high-lift CRM variants is established using Computational Fluid Dynamics (CFD) solutions to the Reynolds-Averaged Navier-Stokes (RANS) equations for steady flow. These CFD assessments identify the high-lift performance that needs to be recovered through AFC to have the CRM variant with the lighter and mechanically simpler high-lift system match the performance of the conventional high-lift system. Conceptual design integration studies for the AFC-enhanced high-lift systems were conducted with a NASA Environmentally Responsible Aircraft (ERA) reference configuration, the so-called ERA-0003 concept. These design trades identify AFC performance targets that need to be met to produce economically feasible ERA-0003-like concepts with lighter and mechanically simpler high-lift designs that match the performance of conventional high-lift systems. Finally, technical challenges are identified associated with the application of AFC-enabled highlift systems to modern transonic commercial transports for future technology maturation efforts.

  17. High extinction ratio integrated optical modulator for quantum telecommunication systems

    Science.gov (United States)

    Tronev, A.; Parfenov, M.; Agruzov, P.; Ilichev, I.; Shamray, A.

    2018-01-01

    A method for increasing the extinction ratio of integrated optical Mach-Zehnder modulators based on LiNbO3 via the photorefractive effect is proposed. The influence of the photorefractive effect on the X- and Y-splitters of intensity modulators is experimentally studied. An increase in the modulator extinction ratio by 17 dB (from 30 to 47 dB) is obtained. It is shown that fabricated modulators with a high extinction ratio are important for quantum key distribution systems.

  18. Flexible, High-Speed CdSe Nanocrystal Integrated Circuits.

    Science.gov (United States)

    Stinner, F Scott; Lai, Yuming; Straus, Daniel B; Diroll, Benjamin T; Kim, David K; Murray, Christopher B; Kagan, Cherie R

    2015-10-14

    We report large-area, flexible, high-speed analog and digital colloidal CdSe nanocrystal integrated circuits operating at low voltages. Using photolithography and a newly developed process to fabricate vertical interconnect access holes, we scale down device dimensions, reducing parasitic capacitances and increasing the frequency of circuit operation, and scale up device fabrication over 4 in. flexible substrates. We demonstrate amplifiers with ∼7 kHz bandwidth, ring oscillators with <10 μs stage delays, and NAND and NOR logic gates.

  19. Development of highly accurate approximate scheme for computing the charge transfer integral

    Energy Technology Data Exchange (ETDEWEB)

    Pershin, Anton; Szalay, Péter G. [Laboratory for Theoretical Chemistry, Institute of Chemistry, Eötvös Loránd University, P.O. Box 32, H-1518 Budapest (Hungary)

    2015-08-21

    The charge transfer integral is a key parameter required by various theoretical models to describe charge transport properties, e.g., in organic semiconductors. The accuracy of this important property depends on several factors, which include the level of electronic structure theory and internal simplifications of the applied formalism. The goal of this paper is to identify the performance of various approximate approaches of the latter category, while using the high level equation-of-motion coupled cluster theory for the electronic structure. The calculations have been performed on the ethylene dimer as one of the simplest model systems. By studying different spatial perturbations, it was shown that while both energy split in dimer and fragment charge difference methods are equivalent with the exact formulation for symmetrical displacements, they are less efficient when describing transfer integral along the asymmetric alteration coordinate. Since the “exact” scheme was found computationally expensive, we examine the possibility to obtain the asymmetric fluctuation of the transfer integral by a Taylor expansion along the coordinate space. By exploring the efficiency of this novel approach, we show that the Taylor expansion scheme represents an attractive alternative to the “exact” calculations due to a substantial reduction of computational costs, when a considerably large region of the potential energy surface is of interest. Moreover, we show that the Taylor expansion scheme, irrespective of the dimer symmetry, is very accurate for the entire range of geometry fluctuations that cover the space the molecule accesses at room temperature.

  20. A high-performance trench capacitor integrated in a passive integration technology

    International Nuclear Information System (INIS)

    Geiselbrechtinger, Angelika; Büyüktas, Kevni; Allers, Karl-Heinz; Hartung, Wolfgang

    2009-01-01

    The requirements for the electrical characteristics of passive on-chip devices become more and more important. The electrical performance of RF circuits is predominantly restricted by the passives. New technologies and new device concepts are necessary to meet the demands. In this work, a trench capacitor developed for RF applications is presented for the first time. This so-called SilCap (silicon capacitor) device features very high capacitance density, extreme low-voltage dependence, excellent temperature stability, good RF performance and a high breakthrough voltage. First, the device function and the technological concept are introduced. The concept is realized without implementing cost-intensive high-k materials. This trench capacitor is integrated in the front end of line of a passive integration technology. The achieved specific capacitance density is compared to a standard planar capacitor. Performance of the SilCap in terms of quality factor and breakthrough voltage is shown. Finally, reliability data of this trench capacitor are presented with special focus on extrinsic and dielectric lifetime

  1. High-throughput microsatellite genotyping in ecology: improved accuracy, efficiency, standardization and success with low-quantity and degraded DNA.

    Science.gov (United States)

    De Barba, M; Miquel, C; Lobréaux, S; Quenette, P Y; Swenson, J E; Taberlet, P

    2017-05-01

    Microsatellite markers have played a major role in ecological, evolutionary and conservation research during the past 20 years. However, technical constrains related to the use of capillary electrophoresis and a recent technological revolution that has impacted other marker types have brought to question the continued use of microsatellites for certain applications. We present a study for improving microsatellite genotyping in ecology using high-throughput sequencing (HTS). This approach entails selection of short markers suitable for HTS, sequencing PCR-amplified microsatellites on an Illumina platform and bioinformatic treatment of the sequence data to obtain multilocus genotypes. It takes advantage of the fact that HTS gives direct access to microsatellite sequences, allowing unambiguous allele identification and enabling automation of the genotyping process through bioinformatics. In addition, the massive parallel sequencing abilities expand the information content of single experimental runs far beyond capillary electrophoresis. We illustrated the method by genotyping brown bear samples amplified with a multiplex PCR of 13 new microsatellite markers and a sex marker. HTS of microsatellites provided accurate individual identification and parentage assignment and resulted in a significant improvement of genotyping success (84%) of faecal degraded DNA and costs reduction compared to capillary electrophoresis. The HTS approach holds vast potential for improving success, accuracy, efficiency and standardization of microsatellite genotyping in ecological and conservation applications, especially those that rely on profiling of low-quantity/quality DNA and on the construction of genetic databases. We discuss and give perspectives for the implementation of the method in the light of the challenges encountered in wildlife studies. © 2016 John Wiley & Sons Ltd.

  2. Strategies for achieving high sequencing accuracy for low diversity samples and avoiding sample bleeding using illumina platform.

    Science.gov (United States)

    Mitra, Abhishek; Skrzypczak, Magdalena; Ginalski, Krzysztof; Rowicka, Maga

    2015-01-01

    Sequencing microRNA, reduced representation sequencing, Hi-C technology and any method requiring the use of in-house barcodes result in sequencing libraries with low initial sequence diversity. Sequencing such data on the Illumina platform typically produces low quality data due to the limitations of the Illumina cluster calling algorithm. Moreover, even in the case of diverse samples, these limitations are causing substantial inaccuracies in multiplexed sample assignment (sample bleeding). Such inaccuracies are unacceptable in clinical applications, and in some other fields (e.g. detection of rare variants). Here, we discuss how both problems with quality of low-diversity samples and sample bleeding are caused by incorrect detection of clusters on the flowcell during initial sequencing cycles. We propose simple software modifications (Long Template Protocol) that overcome this problem. We present experimental results showing that our Long Template Protocol remarkably increases data quality for low diversity samples, as compared with the standard analysis protocol; it also substantially reduces sample bleeding for all samples. For comprehensiveness, we also discuss and compare experimental results from alternative approaches to sequencing low diversity samples. First, we discuss how the low diversity problem, if caused by barcodes, can be avoided altogether at the barcode design stage. Second and third, we present modified guidelines, which are more stringent than the manufacturer's, for mixing low diversity samples with diverse samples and lowering cluster density, which in our experience consistently produces high quality data from low diversity samples. Fourth and fifth, we present rescue strategies that can be applied when sequencing results in low quality data and when there is no more biological material available. In such cases, we propose that the flowcell be re-hybridized and sequenced again using our Long Template Protocol. Alternatively, we discuss how

  3. Strategies for achieving high sequencing accuracy for low diversity samples and avoiding sample bleeding using illumina platform.

    Directory of Open Access Journals (Sweden)

    Abhishek Mitra

    Full Text Available Sequencing microRNA, reduced representation sequencing, Hi-C technology and any method requiring the use of in-house barcodes result in sequencing libraries with low initial sequence diversity. Sequencing such data on the Illumina platform typically produces low quality data due to the limitations of the Illumina cluster calling algorithm. Moreover, even in the case of diverse samples, these limitations are causing substantial inaccuracies in multiplexed sample assignment (sample bleeding. Such inaccuracies are unacceptable in clinical applications, and in some other fields (e.g. detection of rare variants. Here, we discuss how both problems with quality of low-diversity samples and sample bleeding are caused by incorrect detection of clusters on the flowcell during initial sequencing cycles. We propose simple software modifications (Long Template Protocol that overcome this problem. We present experimental results showing that our Long Template Protocol remarkably increases data quality for low diversity samples, as compared with the standard analysis protocol; it also substantially reduces sample bleeding for all samples. For comprehensiveness, we also discuss and compare experimental results from alternative approaches to sequencing low diversity samples. First, we discuss how the low diversity problem, if caused by barcodes, can be avoided altogether at the barcode design stage. Second and third, we present modified guidelines, which are more stringent than the manufacturer's, for mixing low diversity samples with diverse samples and lowering cluster density, which in our experience consistently produces high quality data from low diversity samples. Fourth and fifth, we present rescue strategies that can be applied when sequencing results in low quality data and when there is no more biological material available. In such cases, we propose that the flowcell be re-hybridized and sequenced again using our Long Template Protocol. Alternatively

  4. High-accuracy single-pass InSAR DEM for large-scale flood hazard applications

    Science.gov (United States)

    Schumann, G.; Faherty, D.; Moller, D.

    2017-12-01

    In this study, we used a unique opportunity of the GLISTIN-A (NASA airborne mission designed to characterizing the cryosphere) track to Greenland to acquire a high-resolution InSAR DEM of a large area in the Red River of the North Basin (north of Grand Forks, ND, USA), which is a very flood-vulnerable valley, particularly in spring time due to increased soil moisture content near state of saturation and/or, typical for this region, snowmelt. Having an InSAR DEM that meets flood inundation modeling and mapping requirements comparable to LiDAR, would demonstrate great application potential of new radar technology for national agencies with an operational flood forecasting mandate and also local state governments active in flood event prediction, disaster response and mitigation. Specifically, we derived a bare-earth DEM in SAR geometry by first removing the inherent far range bias related to airborne operation, which at the more typical large-scale DEM resolution of 30 m has a sensor accuracy of plus or minus 2.5 cm. Subsequently, an intelligent classifier based on informed relationships between InSAR height, intensity and correlation was used to distinguish between bare-earth, roads or embankments, buildings and tall vegetation in order to facilitate the creation of a bare-earth DEM that would meet the requirements for accurate floodplain inundation mapping. Using state-of-the-art LiDAR terrain data, we demonstrate that capability by achieving a root mean squared error of approximately 25 cm and further illustrating its applicability to flood modeling.

  5. Improvements in dose calculation accuracy for small off-axis targets in high dose per fraction tomotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Hardcastle, Nicholas; Bayliss, Adam; Wong, Jeannie Hsiu Ding; Rosenfeld, Anatoly B.; Tome, Wolfgang A. [Department of Human Oncology, University of Wisconsin-Madison, WI, 53792 (United States); Department of Physical Sciences, Peter MacCallum Cancer Centre, Melbourne, VIC 3002 (Australia) and Centre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW 2522 (Australia); Department of Human Oncology, University of Wisconsin-Madison, WI 53792 (United States); Centre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW 2522 (Australia) and Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur (Malaysia); Centre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW 2522 (Australia); Department of Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin 53792 (United States); Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53792 (United States); Einstein Institute of Oncophysics, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York 10461 (United States) and Centre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW 2522 (Australia)

    2012-08-15

    Purpose: A recent field safety notice from TomoTherapy detailed the underdosing of small, off-axis targets when receiving high doses per fraction. This is due to angular undersampling in the dose calculation gantry angles. This study evaluates a correction method to reduce the underdosing, to be implemented in the current version (v4.1) of the TomoTherapy treatment planning software. Methods: The correction method, termed 'Super Sampling' involved the tripling of the number of gantry angles from which the dose is calculated during optimization and dose calculation. Radiochromic film was used to measure the dose to small targets at various off-axis distances receiving a minimum of 21 Gy in one fraction. Measurements were also performed for single small targets at the center of the Lucy phantom, using radiochromic film and the dose magnifying glass (DMG). Results: Without super sampling, the peak dose deficit increased from 0% to 18% for a 10 mm target and 0% to 30% for a 5 mm target as off-axis target distances increased from 0 to 16.5 cm. When super sampling was turned on, the dose deficit trend was removed and all peak doses were within 5% of the planned dose. For measurements in the Lucy phantom at 9.7 cm off-axis, the positional and dose magnitude accuracy using super sampling was verified using radiochromic film and the DMG. Conclusions: A correction method implemented in the TomoTherapy treatment planning system which triples the angular sampling of the gantry angles used during optimization and dose calculation removes the underdosing for targets as small as 5 mm diameter, up to 16.5 cm off-axis receiving up to 21 Gy.

  6. Improvements in dose calculation accuracy for small off-axis targets in high dose per fraction tomotherapy

    International Nuclear Information System (INIS)

    Hardcastle, Nicholas; Bayliss, Adam; Wong, Jeannie Hsiu Ding; Rosenfeld, Anatoly B.; Tomé, Wolfgang A.

    2012-01-01

    Purpose: A recent field safety notice from TomoTherapy detailed the underdosing of small, off-axis targets when receiving high doses per fraction. This is due to angular undersampling in the dose calculation gantry angles. This study evaluates a correction method to reduce the underdosing, to be implemented in the current version (v4.1) of the TomoTherapy treatment planning software. Methods: The correction method, termed “Super Sampling” involved the tripling of the number of gantry angles from which the dose is calculated during optimization and dose calculation. Radiochromic film was used to measure the dose to small targets at various off-axis distances receiving a minimum of 21 Gy in one fraction. Measurements were also performed for single small targets at the center of the Lucy phantom, using radiochromic film and the dose magnifying glass (DMG). Results: Without super sampling, the peak dose deficit increased from 0% to 18% for a 10 mm target and 0% to 30% for a 5 mm target as off-axis target distances increased from 0 to 16.5 cm. When super sampling was turned on, the dose deficit trend was removed and all peak doses were within 5% of the planned dose. For measurements in the Lucy phantom at 9.7 cm off-axis, the positional and dose magnitude accuracy using super sampling was verified using radiochromic film and the DMG. Conclusions: A correction method implemented in the TomoTherapy treatment planning system which triples the angular sampling of the gantry angles used during optimization and dose calculation removes the underdosing for targets as small as 5 mm diameter, up to 16.5 cm off-axis receiving up to 21 Gy.

  7. Coupling Ideality of Integrated Planar High-Q Microresonators

    Science.gov (United States)

    Pfeiffer, Martin H. P.; Liu, Junqiu; Geiselmann, Michael; Kippenberg, Tobias J.

    2017-02-01

    Chip-scale optical microresonators with integrated planar optical waveguides are useful building blocks for linear, nonlinear, and quantum-optical photonic devices alike. Loss reduction through improving fabrication processes results in several integrated microresonator platforms attaining quality (Q ) factors of several millions. Beyond the improvement of the quality factor, the ability to operate the microresonator with high coupling ideality in the overcoupled regime is of central importance. In this regime, the dominant source of loss constitutes the coupling to a single desired output channel, which is particularly important not only for quantum-optical applications such as the generation of squeezed light and correlated photon pairs but also for linear and nonlinear photonics. However, to date, the coupling ideality in integrated photonic microresonators is not well understood, in particular, design-dependent losses and their impact on the regime of high ideality. Here we investigate design-dependent parasitic losses described by the coupling ideality of the commonly employed microresonator design consisting of a microring-resonator waveguide side coupled to a straight bus waveguide, a system which is not properly described by the conventional input-output theory of open systems due to the presence of higher-order modes. By systematic characterization of multimode high-Q silicon nitride microresonator devices, we show that this design can suffer from low coupling ideality. By performing 3D simulations, we identify the coupling to higher-order bus waveguide modes as the dominant origin of parasitic losses which lead to the low coupling ideality. Using suitably designed bus waveguides, parasitic losses are mitigated with a nearly unity ideality and strong overcoupling (i.e., a ratio of external coupling to internal resonator loss rate >9 ) are demonstrated. Moreover, we find that different resonator modes can exchange power through the coupler, which, therefore

  8. High-level waste program integration within the DOE complex

    International Nuclear Information System (INIS)

    Valentine, J.H.; Malone, K.; Schaus, P.S.

    1998-03-01

    Eleven major Department of Energy (DOE) site contractors were chartered by the Assistant Secretary to use a systems engineering approach to develop and evaluate technically defensible cost savings opportunities across the complex. Known as the complex-wide Environmental Management Integration (EMI), this process evaluated all the major DOE waste streams including high level waste (HLW). Across the DOE complex, this waste stream has the highest life cycle cost and is scheduled to take until at least 2035 before all HLW is processed for disposal. Technical contract experts from the four DOE sites that manage high level waste participated in the integration analysis: Hanford, Savannah River Site (SRS), Idaho National Engineering and Environmental Laboratory (INEEL), and West Valley Demonstration Project (WVDP). In addition, subject matter experts from the Yucca Mountain Project and the Tanks Focus Area participated in the analysis. Also, departmental representatives from the US Department of Energy Headquarters (DOE-HQ) monitored the analysis and results. Workouts were held throughout the year to develop recommendations to achieve a complex-wide integrated program. From this effort, the HLW Environmental Management (EM) Team identified a set of programmatic and technical opportunities that could result in potential cost savings and avoidance in excess of $18 billion and an accelerated completion of the HLW mission by seven years. The cost savings, schedule improvements, and volume reduction are attributed to a multifaceted HLW treatment disposal strategy which involves waste pretreatment, standardized waste matrices, risk-based retrieval, early development and deployment of a shipping system for glass canisters, and reasonable, low cost tank closure

  9. Physics of integrated high-performance NSTX plasmas

    International Nuclear Information System (INIS)

    Menard, J. E.; Bell, M. G.; Bell, R. E.; Fredrickson, E. D.; Gates, D. A.; Heidbrink, W.; Kaita, R.; Kaye, S. M.; Kessel, C. E.; Kugel, H.; LeBlanc, B. P.; Lee, K. C.; Levinton, F. M.; Maingi, R.; Medley, S. S.; Mikkelsen, D. R.; Mueller, D.; Nishino, N.; Ono, M.; Park, H.; Park, W.; Paul, S. F.; Peebles, T.; Peng, M.; Raman, R.; Redi, M.; Roquemore, L.; Sabbagh, S. A.; Skiner, C. H.; Sontag, A.; Soukhanovskii, V.; Stratton, B.; Stutman, D.; Synakowski, E.; Takase, Y.; Taylor, G.; Tritz, K.; Wade, M.; Wilson, J. R.; Zhu, W.

    2005-01-01

    An overarching goal of magnetic fusion research is the integration of steady state operation with high fusion power density, high plasma β, good thermal and fast particle confinement, and manageable heat and particle fluxes to reactor internal components. NSTX has made significant progress in integrating and understanding the interplay between these competing elements. Sustained high elongation up to 2.5 and H-mode transitions during the I p ramp-up have increased β p and reduced l i at high current resulting in I p flat-top durations exceeding 0.8s for I p >0.8MA. These shape and profile changes delay the onset of deleterious global MHD activity yielding β N values >4.5 and β T ∼20% maintained for several current diffusion times. Higher ∫ N discharges operating above the non-wall limit are sustained via rotational stabilization of the RWM. H-mode confinement scaling factors relative to H98(y,2) span the range 1±0.4 for B T >4kG and show a stron (Nearly linear) residual scaling with B T . Power balance analysis indicates the electron thermal transport dominates the loss power in beam-heated H m ode discharges, but the core χ e can be significantly reduced through current profile modification consistent with reversed magnetic shear. Small ELM regimes have been obtained in high performance plasmas on NSTX, but the ELM type and associated pedestal energy loss are found to depend sensitively on the boundary elongation, magnetic balance, and edge collisionality. NPA data and TRANSP analysis suggest resonant interactions with mid-radius tearing modes may lead to large fast-ion transport. The associated fast-ion diffusion and/or loss likely impact(s) both the driven current and power deposition profiles from NBI heating. Results from experiments to initiate the plasma without the ohmic solenoid and integrated scenario with the TSC code will also be described. (Author)

  10. Verification and validation guidelines for high integrity systems. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Hecht, H.; Hecht, M.; Dinsmore, G.; Hecht, S.; Tang, D. [SoHaR, Inc., Beverly Hills, CA (United States)

    1995-03-01

    High integrity systems include all protective (safety and mitigation) systems for nuclear power plants, and also systems for which comparable reliability requirements exist in other fields, such as in the process industries, in air traffic control, and in patient monitoring and other medical systems. Verification aims at determining that each stage in the software development completely and correctly implements requirements that were established in a preceding phase, while validation determines that the overall performance of a computer system completely and correctly meets system requirements. Volume I of the report reviews existing classifications for high integrity systems and for the types of errors that may be encountered, and makes recommendations for verification and validation procedures, based on assumptions about the environment in which these procedures will be conducted. The final chapter of Volume I deals with a framework for standards in this field. Volume II contains appendices dealing with specific methodologies for system classification, for dependability evaluation, and for two software tools that can automate otherwise very labor intensive verification and validation activities.

  11. Verification and validation guidelines for high integrity systems. Volume 1

    International Nuclear Information System (INIS)

    Hecht, H.; Hecht, M.; Dinsmore, G.; Hecht, S.; Tang, D.

    1995-03-01

    High integrity systems include all protective (safety and mitigation) systems for nuclear power plants, and also systems for which comparable reliability requirements exist in other fields, such as in the process industries, in air traffic control, and in patient monitoring and other medical systems. Verification aims at determining that each stage in the software development completely and correctly implements requirements that were established in a preceding phase, while validation determines that the overall performance of a computer system completely and correctly meets system requirements. Volume I of the report reviews existing classifications for high integrity systems and for the types of errors that may be encountered, and makes recommendations for verification and validation procedures, based on assumptions about the environment in which these procedures will be conducted. The final chapter of Volume I deals with a framework for standards in this field. Volume II contains appendices dealing with specific methodologies for system classification, for dependability evaluation, and for two software tools that can automate otherwise very labor intensive verification and validation activities

  12. High integrity container evaluation for solid waste disposal burial containers

    International Nuclear Information System (INIS)

    Josephson, W.S.

    1996-01-01

    In order to provide radioactive waste disposal practices with the greatest measure of public protection, Solid Waste Disposal (SWD) adopted the Nuclear Regulatory Commission (NRC) requirement to stabilize high specific activity radioactive waste prior to disposal. Under NRC guidelines, stability may be provided by several mechanisms, one of which is by placing the waste in a high integrity container (HIC). During the implementation process, SWD found that commercially-available HICs could not accommodate the varied nature of weapons complex waste, and in response developed a number of disposal containers to function as HICs. This document summarizes the evaluation of various containers that can be used for the disposal of Category 3 waste in the Low Level Burial Grounds. These containers include the VECTRA reinforced concrete HIC, reinforced concrete culvert, and the reinforced concrete vault. This evaluation provides justification for the use of these containers and identifies the conditions for use of each

  13. Liquid theory with high accuracy and broad applicability: Coupling parameter series expansion and non hard sphere perturbation strategy

    Directory of Open Access Journals (Sweden)

    Shiqi Zhou

    2011-12-01

    Full Text Available Thermodynamic and structural properties of liquids are of fundamental interest in physics, chemistry, and biology, and perturbation approach has been fundamental to liquid theoretical approaches since the dawn of modern statistical mechanics and remains so to this day. Although thermodynamic perturbation theory (TPT is widely used in the chemical physics community, one of the most popular versions of the TPT, i.e. Zwanzig (Zwanzig, R. W. J. Chem. Phys. 1954, 22, 1420-1426 1st-order high temperature series expansion (HTSE TPT and its 2nd-order counterpart under a macroscopic compressibility approximation of Barker-Henderson (Barker, J. A.; Henderson, D. J. Chem. Phys. 1967, 47, 2856-2861, have some serious shortcomings: (i the nth-order term of the HTSE is involved with reference fluid distribution functions of order up to 2n, and the higher-order terms hence progressively become more complicated and numerically inaccessible; (ii the performance of the HTSE rapidly deteriorates and the calculated results become even qualitatively incorrect as the temperature of interest decreases. This account deals with the developments that we have made over the last five years or so to advance a coupling parameter series expansion (CPSE and a non hard sphere (HS perturbation strategy that has scored some of its greatest successes in overcoming the above-mentioned difficulties. In this account (i we expatiate on implementation details of our schemes: how input information indispensable to high-order truncation of the CPSE in both the HS and non HS perturbation schemes is calculated by an Ornstein-Zernike integral equation theory; how high-order thermodynamic quantities, such as critical parameters and excess constant volume heat capacity, are extracted from the resulting excess Helmholtz free energy with irregular and inevitable numerical errors; how to select reference potential in the non HS perturbation scheme. (ii We give a quantitative analysis on why

  14. A highly accurate boundary integral equation method for surfactant-laden drops in 3D

    Science.gov (United States)

    Sorgentone, Chiara; Tornberg, Anna-Karin

    2018-05-01

    The presence of surfactants alters the dynamics of viscous drops immersed in an ambient viscous fluid. This is specifically true at small scales, such as in applications of droplet based microfluidics, where the interface dynamics become of increased importance. At such small scales, viscous forces dominate and inertial effects are often negligible. Considering Stokes flow, a numerical method based on a boundary integral formulation is presented for simulating 3D drops covered by an insoluble surfactant. The method is able to simulate drops with different viscosities and close interactions, automatically controlling the time step size and maintaining high accuracy also when substantial drop deformation appears. To achieve this, the drop surfaces as well as the surfactant concentration on each surface are represented by spherical harmonics expansions. A novel reparameterization method is introduced to ensure a high-quality representation of the drops also under deformation, specialized quadrature methods for singular and nearly singular integrals that appear in the formulation are evoked and the adaptive time stepping scheme for the coupled drop and surfactant evolution is designed with a preconditioned implicit treatment of the surfactant diffusion.

  15. Integration Test of the High Voltage Hall Accelerator System Components

    Science.gov (United States)

    Kamhawi, Hani; Haag, Thomas; Huang, Wensheng; Pinero, Luis; Peterson, Todd; Dankanich, John

    2013-01-01

    NASA Glenn Research Center is developing a 4 kilowatt-class Hall propulsion system for implementation in NASA science missions. NASA science mission performance analysis was completed using the latest high voltage Hall accelerator (HiVHAc) and Aerojet-Rocketdyne's state-of-the-art BPT-4000 Hall thruster performance curves. Mission analysis results indicated that the HiVHAc thruster out performs the BPT-4000 thruster for all but one of the missions studied. Tests of the HiVHAc system major components were performed. Performance evaluation of the HiVHAc thruster at NASA Glenn's vacuum facility 5 indicated that thruster performance was lower than performance levels attained during tests in vacuum facility 12 due to the lower background pressures attained during vacuum facility 5 tests when compared to vacuum facility 12. Voltage-Current characterization of the HiVHAc thruster in vacuum facility 5 showed that the HiVHAc thruster can operate stably for a wide range of anode flow rates for discharge voltages between 250 and 600 volts. A Colorado Power Electronics enhanced brassboard power processing unit was tested in vacuum for 1,500 hours and the unit demonstrated discharge module efficiency of 96.3% at 3.9 kilowatts and 650 volts. Stand-alone open and closed loop tests of a VACCO TRL 6 xenon flow control module were also performed. An integrated test of the HiVHAc thruster, brassboard power processing unit, and xenon flow control module was performed and confirmed that integrated operation of the HiVHAc system major components. Future plans include continuing the maturation of the HiVHAc system major components and the performance of a single-string integration test.

  16. Spatial variability in sensitivity of reference crop ET to accuracy of climate data in the Texas High Plains

    Science.gov (United States)

    A detailed sensitivity analysis was conducted to determine the relative effects of measurement errors in climate data input parameters on the accuracy of calculated reference crop evapotranspiration (ET) using the ASCE-EWRI Standardized Reference ET Equation. Data for the period of 1995 to 2008, fro...

  17. Transformation Model with Constraints for High-Accuracy of 2D-3D Building Registration in Aerial Imagery

    Directory of Open Access Journals (Sweden)

    Guoqing Zhou

    2016-06-01

    Full Text Available This paper proposes a novel rigorous transformation model for 2D-3D registration to address the difficult problem of obtaining a sufficient number of well-distributed ground control points (GCPs in urban areas with tall buildings. The proposed model applies two types of geometric constraints, co-planarity and perpendicularity, to the conventional photogrammetric collinearity model. Both types of geometric information are directly obtained from geometric building structures, with which the geometric constraints are automatically created and combined into the conventional transformation model. A test field located in downtown Denver, Colorado, is used to evaluate the accuracy and reliability of the proposed method. The comparison analysis of the accuracy achieved by the proposed method and the conventional method is conducted. Experimental results demonstrated that: (1 the theoretical accuracy of the solved registration parameters can reach 0.47 pixels, whereas the other methods reach only 1.23 and 1.09 pixels; (2 the RMS values of 2D-3D registration achieved by the proposed model are only two pixels along the x and y directions, much smaller than the RMS values of the conventional model, which are approximately 10 pixels along the x and y directions. These results demonstrate that the proposed method is able to significantly improve the accuracy of 2D-3D registration with much fewer GCPs in urban areas with tall buildings.

  18. Continuous assessment of land mapping accuracy at High Resolution from global networks of atmospheric and field observatories -concept and demonstration

    Science.gov (United States)

    Sicard, Pierre; Martin-lauzer, François-regis

    2017-04-01

    In the context of global climate change and adjustment/resilience policies' design and implementation, there is a need not only i. for environmental monitoring, e.g. through a range of Earth Observations (EO) land "products" but ii. for a precise assessment of uncertainties of the aforesaid information that feed environmental decision-making (to be introduced in the EO metadata) and also iii. for a perfect handing of the thresholds which help translate "environment tolerance limits" to match detected EO changes through ecosystem modelling. Uncertainties' insight means precision and accuracy's knowledge and subsequent ability of setting thresholds for change detection systems. Traditionally, the validation of satellite-derived products has taken the form of intensive field campaigns to sanction the introduction of data processors in Payload Data Ground Segments chains. It is marred by logistical challenges and cost issues, reason why it is complemented by specific surveys at ground-based monitoring sites which can provide near-continuous observations at a high temporal resolution (e.g. RadCalNet). Unfortunately, most of the ground-level monitoring sites, in the number of 100th or 1000th, which are part of wider observation networks (e.g. FLUXNET, NEON, IMAGINES) mainly monitor the state of the atmosphere and the radiation exchange at the surface, which are different to the products derived from EO data. In addition they are "point-based" compared to the EO cover to be obtained from Sentinel-2 or Sentinel-3. Yet, data from these networks, processed by spatial extrapolation models, are well-suited to the bottom-up approach and relevant to the validation of vegetation parameters' consistency (e.g. leaf area index, fraction of absorbed photosynthetically active radiation). Consistency means minimal errors on spatial and temporal gradients of EO products. Test of the procedure for land-cover products' consistency assessment with field measurements delivered by worldwide

  19. Improved accuracy of cortical bone mineralization measured by polychromatic microcomputed tomography using a novel high mineral density composite calibration phantom

    International Nuclear Information System (INIS)

    Deuerling, Justin M.; Rudy, David J.; Niebur, Glen L.; Roeder, Ryan K.

    2010-01-01

    Purpose: Microcomputed tomography (micro-CT) is increasingly used as a nondestructive alternative to ashing for measuring bone mineral content. Phantoms are utilized to calibrate the measured x-ray attenuation to discrete levels of mineral density, typically including levels up to 1000 mg HA/cm 3 , which encompasses levels of bone mineral density (BMD) observed in trabecular bone. However, levels of BMD observed in cortical bone and levels of tissue mineral density (TMD) in both cortical and trabecular bone typically exceed 1000 mg HA/cm 3 , requiring extrapolation of the calibration regression, which may result in error. Therefore, the objectives of this study were to investigate (1) the relationship between x-ray attenuation and an expanded range of hydroxyapatite (HA) density in a less attenuating polymer matrix and (2) the effects of the calibration on the accuracy of subsequent measurements of mineralization in human cortical bone specimens. Methods: A novel HA-polymer composite phantom was prepared comprising a less attenuating polymer phase (polyethylene) and an expanded range of HA density (0-1860 mg HA/cm 3 ) inclusive of characteristic levels of BMD in cortical bone or TMD in cortical and trabecular bone. The BMD and TMD of cortical bone specimens measured using the new HA-polymer calibration phantom were compared to measurements using a conventional HA-polymer phantom comprising 0-800 mg HA/cm 3 and the corresponding ash density measurements on the same specimens. Results: The HA-polymer composite phantom exhibited a nonlinear relationship between x-ray attenuation and HA density, rather than the linear relationship typically employed a priori, and obviated the need for extrapolation, when calibrating the measured x-ray attenuation to high levels of mineral density. The BMD and TMD of cortical bone specimens measured using the conventional phantom was significantly lower than the measured ash density by 19% (p<0.001, ANCOVA) and 33% (p<0.05, Tukey's HSD

  20. A new high precision energy-preserving integrator for system of oscillatory second-order differential equations

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Bin, E-mail: wangbinmaths@gmail.com [Department of Mathematics, Nanjing University, State Key Laboratory for Novel Software Technology at Nanjing University, Nanjing 210093 (China); Wu, Xinyuan, E-mail: xywu@nju.edu.cn [Department of Mathematics, Nanjing University, State Key Laboratory for Novel Software Technology at Nanjing University, Nanjing 210093 (China)

    2012-03-05

    This Letter proposes a new high precision energy-preserving integrator for system of oscillatory second-order differential equations q{sup ″}(t)+Mq(t)=f(q(t)) with a symmetric and positive semi-definite matrix M and f(q)=−∇U(q). The system is equivalent to a separable Hamiltonian system with Hamiltonian H(p,q)=1/2 p{sup T}p+1/2 q{sup T}Mq+U(q). The properties of the new energy-preserving integrator are analyzed. The well-known Fermi–Pasta–Ulam problem is performed numerically to show that the new integrator preserves the energy integral with higher accuracy than Average Vector Field (AVF) method and an energy-preserving collocation method. -- Highlights: ► A novel high order energy-preserving integrator AAVF-GL is proposed. ► The important properties of the new integrator AAVF-GL are shown. ► Numerical experiment is carried out compared with AVF method etc. appeared recently.

  1. High-accuracy continuous airborne measurements of greenhouse gases (CO2 and CH4) using the cavity ring-down spectroscopy (CRDS) technique

    NARCIS (Netherlands)

    Chen, H.; Winderlich, J.; Gerbig, C.; Hoefer, A.; Rella, C. W.; Crosson, E. R.; Van Pelt, A. D.; Steinbach, J.; Kolle, O.; Beck, V.; Daube, B. C.; Gottlieb, E. W.; Chow, V. Y.; Santoni, G. W.; Wofsy, S. C.

    2010-01-01

    High-accuracy continuous measurements of greenhouse gases (CO2 and CH4) during the BARCA (Balancao Atmosferico Regional de Carbono na Amazonia) phase B campaign in Brazil in May 2009 were accomplished using a newly available analyzer based on the cavity ring-down spectroscopy (CRDS) technique. This

  2. Hybrid High-Impact Pedagogies: Integrating Service-Learning with Three Other High-Impact Pedagogies

    Science.gov (United States)

    Bringle, Robert G.

    2017-01-01

    This article proposes enhancing student learning through civic engagement by considering the advantages of integrating service-learning with study away, research, and internships and pre-professional courses into first-order, second-order, and third-order hybrid high-impact pedagogies. Service-learning contributes numerous attributes to the other…

  3. Central system of Interlock of ITER, high integrity architecture

    International Nuclear Information System (INIS)

    Prieto, I.; Martinez, G.; Lopez, C.

    2014-01-01

    The CIS (Central Interlock System), along with the CODAC system and CSS (Central Safety System), form the central I and C systems of ITER. The CIS is responsible for implementing the core functions of protection (Central Interlock Functions) through different systems of plant (Plant Systems) within the overall strategy of investment protection for ITER. IBERDROLA supports engineering to define and develop the control architecture of CIS according to the stringent requirements of integrity, availability and response time. For functions with response times of the order of half a second is selected PLC High availability of industrial range. However, due to the nature of the machine itself, certain functions must be able to act under the millisecond, so it has had to develop a solution based on FPGA (Field Programmable Gate Array) capable of meeting the requirements architecture. In this article CIS architecture is described, as well as the process for the development and validation of the selected platforms. (Author)

  4. Astronomy: social background of students of the integrated high school

    Science.gov (United States)

    Voelzke, M. R.; Barbosa, J. I. L.

    2017-07-01

    Astronomy-related contents exist in almost all levels of basic education in Brazil and are also frequently disseminated through mass media. Thus, students form their own explanations about the phenomena studied by this science. Therefore, this work has the objective of identifying the possible social background of the Integrated High School students on the term Astronomy. It is a research of a basic nature, descriptive, and for that reason a quali-quantitative approach was adopted; the procedures to obtain the data were effected in the form of a survey. The results show that the tested students have a social background about the object Astronomy, which is on the one hand fortified by elements they have made or which is part of the experience lived by the respondents within the formal space of education, and on the other hand based on elements possibly disseminated through the mass media.

  5. Effect of high temperature on integrity of concrete containment structures

    International Nuclear Information System (INIS)

    Bhat, P.D.

    1986-01-01

    The effect of high temperature on concrete material properties and structural behavior are studied in order to relate these effects to the performance of concrete containment structures. Salient data obtained from a test program undertaken to study the behavior of a restrained concrete structure under thermal gradient loads up to its ultimate limit are described. The preliminary results indicate that concrete material properties can be considered to remain unaltered up to temperatures of 100 0 C. The presence of thermal gradients did not significantly affect the structures ultimate mechanical load capacity. Relaxation of restraint forces due to creep was found to be an important factor. The test findings are compared with the observations made in available literature. The effect of test findings on the integrity analysis of a containment structure are discussed. The problem is studied from the viewpoint of a CANDU heavy water reactor containment

  6. An Integrated Tone Mapping for High Dynamic Range Image Visualization

    Science.gov (United States)

    Liang, Lei; Pan, Jeng-Shyang; Zhuang, Yongjun

    2018-01-01

    There are two type tone mapping operators for high dynamic range (HDR) image visualization. HDR image mapped by perceptual operators have strong sense of reality, but will lose local details. Empirical operators can maximize local detail information of HDR image, but realism is not strong. A common tone mapping operator suitable for all applications is not available. This paper proposes a novel integrated tone mapping framework which can achieve conversion between empirical operators and perceptual operators. In this framework, the empirical operator is rendered based on improved saliency map, which simulates the visual attention mechanism of the human eye to the natural scene. The results of objective evaluation prove the effectiveness of the proposed solution.

  7. Empty substrate integrated waveguide technology for E plane high-frequency and high-performance circuits

    Science.gov (United States)

    Belenguer, Angel; Cano, Juan Luis; Esteban, Héctor; Artal, Eduardo; Boria, Vicente E.

    2017-01-01

    Substrate integrated circuits (SIC) have attracted much attention in the last years because of their great potential of low cost, easy manufacturing, integration in a circuit board, and higher-quality factor than planar circuits. A first suite of SIC where the waves propagate through dielectric have been first developed, based on the well-known substrate integrated waveguide (SIW) and related technological implementations. One step further has been made with a new suite of empty substrate integrated waveguides, where the waves propagate through air, thus reducing the associated losses. This is the case of the empty substrate integrated waveguide (ESIW) or the air-filled substrate integrated waveguide (air-filled SIW). However, all these SIC are H plane structures, so classical H plane solutions in rectangular waveguides have already been mapped to most of these new SIC. In this paper a novel E plane empty substrate integrated waveguide (ESIW-E) is presented. This structure allows to easily map classical E plane solutions in rectangular waveguide to this new substrate integrated solution. It is similar to the ESIW, although more layers are needed to build the structure. A wideband transition (covering the frequency range between 33 GHz and 50 GHz) from microstrip to ESIW-E is designed and manufactured. Measurements are successfully compared with simulation, proving the validity of this new SIC. A broadband high-frequency phase shifter (for operation from 35 GHz to 47 GHz) is successfully implemented in ESIW-E, thus proving the good performance of this new SIC in a practical application.

  8. High accuracy results for the energy levels of the molecular ions H+2, D+2 and HD+, up to J = 2

    International Nuclear Information System (INIS)

    Karr, J Ph; Hilico, L

    2006-01-01

    We present a nonrelativistic calculation of the rotation-vibration levels of the molecular ions H + 2 , D + 2 and HD + , relying on the diagonalization of the exact three-body Hamiltonian in a variational basis. The J = 2 levels are obtained with a very high accuracy of 10 -14 au (for most levels) representing an improvement by five orders of magnitude over previous calculations. The accuracy is also improved for the J = 1 levels of H + 2 and D + 2 with respect to earlier works. Moreover, we have computed the sensitivities of the energy levels with respect to the mass ratios, allowing these levels to be used for metrological purposes

  9. IT Requirements Integration in High-Rise Construction Design Projects

    Science.gov (United States)

    Levina, Anastasia; Ilin, Igor; Esedulaev, Rustam

    2018-03-01

    The paper discusses the growing role of IT support for the operation of modern high-rise buildings, due to the complexity of managing engineering systems of buildings and the requirements of consumers for the IT infrastructure. The existing regulatory framework for the development of design documentation for construction, including high-rise buildings, is analyzed, and the lack of coherence in the development of this documentation with the requirements for the creation of an automated management system and the corresponding IT infrastructure is stated. The lack of integration between these areas is the cause of delays and inefficiencies both at the design stage and at the stage of putting the building into operation. The paper proposes an approach to coordinate the requirements of the IT infrastructure of high-rise buildings and design documentation for construction. The solution to this problem is possible within the framework of the enterprise architecture concept by coordinating the requirements of the IT and technological layers at the design stage of the construction.

  10. AGILE integration into APC for high mix logic fab

    Science.gov (United States)

    Gatefait, M.; Lam, A.; Le Gratiet, B.; Mikolajczak, M.; Morin, V.; Chojnowski, N.; Kocsis, Z.; Smith, I.; Decaunes, J.; Ostrovsky, A.; Monget, C.

    2015-09-01

    mix logic Fab) in term of product and technology portfolio AGILE corrects for up to 120nm of product topography error on process layer with less than 50nm depth of focus Based on tool functionalities delivered by ASML and on high volume manufacturing requirement, AGILE integration is a real challenge. Regarding ST requirements "Automatic AGILE" functionality developed by ASML was not a turnkey solution and a dedicated functionality was needed. A "ST homemade AGILE integration" has been fully developed and implemented within ASML and ST constraints. This paper describes this integration in our Advanced Process Control platform (APC).

  11. Integrated design and manufacturing for the high speed civil transport

    Science.gov (United States)

    1993-01-01

    In June 1992, Georgia Tech's School of Aerospace Engineering was awarded a NASA University Space Research Association (USRA) Advanced Design Program (ADP) to address 'Integrated Design and Manufacturing for the High Speed Civil Transport (HSCT)' in its graduate aerospace systems design courses. This report summarizes the results of the five courses incorporated into the Georgia Tech's USRA ADP program. It covers AE8113: Introduction to Concurrent Engineering, AE4360: Introduction to CAE/CAD, AE4353: Design for Life Cycle Cost, AE6351: Aerospace Systems Design One, and AE6352: Aerospace Systems Design Two. AE8113: Introduction to Concurrent Engineering was an introductory course addressing the basic principles of concurrent engineering (CE) or integrated product development (IPD). The design of a total system was not the objective of this course. The goal was to understand and define the 'up-front' customer requirements, their decomposition, and determine the value objectives for a complex product, such as the high speed civil transport (HSCT). A generic CE methodology developed at Georgia Tech was used for this purpose. AE4353: Design for Life Cycle Cost addressed the basic economic issues for an HSCT using a robust design technique, Taguchi's parameter design optimization method (PDOM). An HSCT economic sensitivity assessment was conducted using a Taguchi PDOM approach to address the robustness of the basic HSCT design. AE4360: Introduction to CAE/CAD permitted students to develop and utilize CAE/CAD/CAM knowledge and skills using CATIA and CADAM as the basic geometric tools. AE6351: Aerospace Systems Design One focused on the conceptual design refinement of a baseline HSCT configuration as defined by Boeing, Douglas, and NASA in their system studies. It required the use of NASA's synthesis codes FLOPS and ACSYNT. A criterion called the productivity index (P.I.) was used to evaluate disciplinary sensitivities and provide refinements of the baseline HSCT

  12. CARETS: A prototype regional environmental information system. Volume 6: Cost, accuracy and consistency comparisons of land use maps made from high-altitude aircraft photography and ERTS imagery

    Science.gov (United States)

    Alexander, R. H. (Principal Investigator); Fitzpatrick, K. A.

    1975-01-01

    The author has identified the following significant results. Level 2 land use maps produced at three scales (1:24,000, 1:100,000, and 1:250,000) from high altitude photography were compared with each other and with point data obtained in the field. The same procedures were employed to determine the accuracy of the Level 1 land use maps produced at 1:250,000 from high altitude photography and color composite ERTS imagery. Accuracy of the Level 2 maps was 84.9 percent at 1:24,000, 77.4 percent at 1:100,000 and 73.0 percent at 1:250,000. Accuracy of the Level 1 1:250,000 maps was 76.5 percent for aerial photographs and 69.5 percent for ERTS imagery. The cost of Level 2 land use mapping at 1:24,000 was found to be high ($11.93 per sq km). The cost of mapping at 1:100,000 ($1.75) was about two times as expensive as mapping at 1:250,000 ($.88), and the accuracy increased by only 4.4 percent.

  13. Accurate mass measurements of very short-lived nuclei. Prerequisites for high-accuracy investigations of superallowed β-decays

    International Nuclear Information System (INIS)

    Herfurth, F.; Kellerbauer, A.; Sauvan, E.; Ames, F.; Engels, O.; Audi, G.; Lunney, D.; Beck, D.; Blaum, K.; Kluge, H.J.; Scheidenberger, C.; Sikler, G.; Weber, C.; Bollen, G.; Schwarz, S.; Moore, R.B.; Oinonen, M.

    2002-01-01

    Mass measurements of 34 Ar, 73-78 Kr, and 74,76 Rb were performed with the Penning-trap mass spectrometer ISOLTRAP. Very accurate Q EC -values are needed for the investigations of the Ft-value of 0 + → 0 + nuclear β-decays used to test the standard model predictions for weak interactions. The necessary accuracy on the Q EC -value requires the mass of mother and daughter nuclei to be measured with δm/m ≤ 3 . 10 -8 . For most of the measured nuclides presented here this has been reached. The 34 Ar mass has been measured with a relative accuracy of 1.1 .10 -8 . The Q EC -value of the 34 Ar 0 + → 0 + decay can now be determined with an uncertainty of about 0.01%. Furthermore, 74 Rb is the shortest-lived nuclide ever investigated in a Penning trap. (orig.)

  14. Accuracy of the solution of the transfer equation for a plane layer of high optical thickness with strongly anisotropic scattering

    International Nuclear Information System (INIS)

    Konovalov, N.V.

    The accuracy of the calculation of the characteristics of a radiation field in a plane layer is investigated by solving the transfer equation in dependence on the error in the specification of the scattering indicatrix. It is shown that a small error in the specification of the indicatrix can lead to a large error in the solution at large optical depths. An estimate is given for the region of optical thicknesses for which the emission field can be determined with sufficient degree of accuracy from the transfer equation with a known error in the specification of the indicatrix. For an estimation of the error involved in various numerical methods, and also for a determination of the region of their applicability, the results of calculations of problems with strongly anisotropic indicatrix are given

  15. Using high-order polynomial basis in 3-D EM forward modeling based on volume integral equation method

    Science.gov (United States)

    Kruglyakov, Mikhail; Kuvshinov, Alexey

    2018-05-01

    3-D interpretation of electromagnetic (EM) data of different origin and scale becomes a common practice worldwide. However, 3-D EM numerical simulations (modeling)—a key part of any 3-D EM data analysis—with realistic levels of complexity, accuracy and spatial detail still remains challenging from the computational point of view. We present a novel, efficient 3-D numerical solver based on a volume integral equation (IE) method. The efficiency is achieved by using a high-order polynomial (HOP) basis instead of the zero-order (piecewise constant) basis that is invoked in all routinely used IE-based solvers. We demonstrate that usage of the HOP basis allows us to decrease substantially the number of unknowns (preserving the same accuracy), with corresponding speed increase and memory saving.

  16. Highly-Integrated Hydraulic Smart Actuators and Smart Manifolds for High-Bandwidth Force Control

    Directory of Open Access Journals (Sweden)

    Victor Barasuol

    2018-06-01

    Full Text Available Hydraulic actuation is the most widely used alternative to electric motors for legged robots and manipulators. It is often selected for its high power density, robustness and high-bandwidth control performance that allows the implementation of force/impedance control. Force control is crucial for robots that are in contact with the environment, since it enables the implementation of active impedance and whole body control that can lead to a better performance in known and unknown environments. This paper presents the hydraulic Integrated Smart Actuator (ISA developed by Moog in collaboration with IIT, as well as smart manifolds for rotary hydraulic actuators. The ISA consists of an additive-manufactured body containing a hydraulic cylinder, servo valve, pressure/position/load/temperature sensing, overload protection and electronics for control and communication. The ISA v2 and ISA v5 have been specifically designed to fit into the legs of IIT’s hydraulic quadruped robots HyQ and HyQ-REAL, respectively. The key features of these components tackle 3 of today’s main challenges of hydraulic actuation for legged robots through: (1 built-in controllers running inside integrated electronics for high-performance control, (2 low-leakage servo valves for reduced energy losses, and (3 compactness thanks to metal additive manufacturing. The main contributions of this paper are the derivation of the representative dynamic models of these highly integrated hydraulic servo actuators, a control architecture that allows for high-bandwidth force control and their experimental validation with application-specific trajectories and tests. We believe that this is the first work that presents additive-manufactured, highly integrated hydraulic smart actuators for robotics.

  17. High-bandwidth piezoresistive force probes with integrated thermal actuation

    International Nuclear Information System (INIS)

    Doll, Joseph C; Pruitt, Beth L

    2012-01-01

    We present high-speed force probes with on-chip actuation and sensing for the measurement of pN-scale forces at the microsecond timescale. We achieve a high resonant frequency in water (1–100 kHz) with requisite low spring constants (0.3–40 pN nm −1 ) and low integrated force noise (1–100 pN) by targeting probe dimensions on the order of 300 nm thick, 1–2 μm wide and 30–200 μm long. Forces are measured using silicon piezoresistors, while the probes are actuated thermally with an aluminum unimorph and silicon heater. The piezoresistive sensors are designed using the open-source numerical optimization code that incorporates constraints on operating temperature. Parylene passivation enables operation in ionic media and we demonstrate simultaneous actuation and sensing. The improved design and fabrication techniques that we describe enable a 10–20-fold improvement in force resolution or measurement bandwidth over prior piezoresistive cantilevers of comparable thickness. (paper)

  18. High bandwidth piezoresistive force probes with integrated thermal actuation

    Science.gov (United States)

    Doll, Joseph C.; Pruitt, Beth L.

    2012-01-01

    We present high-speed force probes with on-chip actuation and sensing for the measurement of pN-scale forces at the microsecond time scale. We achieve a high resonant frequency in water (1–100 kHz) with requisite low spring constants (0.3–40 pN/nm) and low integrated force noise (1–100 pN) by targeting probe dimensions on the order of 300 nm thick, 1–2 μm wide and 30–200 μm long. Forces are measured using silicon piezoresistors while the probes are actuated thermally with an aluminum unimorph and silicon heater. The piezoresistive sensors are designed using open source numerical optimization code that incorporates constraints on operating temperature. Parylene passivation enables operation in ionic media and we demonstrate simultaneous actuation and sensing. The improved design and fabrication techniques that we describe enable a 10–20 fold improvement in force resolution or measurement bandwidth over prior piezoresistive cantilevers of comparable thickness. PMID:23175616

  19. Integrated Circuit Design in US High-Energy Physics

    Energy Technology Data Exchange (ETDEWEB)

    Geronimo, G. D. [Brookhaven National Lab. (BNL), Upton, NY (United States); Christian, D. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Bebek, C. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Garcia-Sciveres, M. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Lippe, H. V. D. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Haller, G. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Grillo, AA [Univ. of California, Santa Cruz, CA (United States); Newcomer, M [Univ. of Pennsylvania, Philadelphia, PA (United States)

    2013-07-10

    This whitepaper summarizes the status, plans, and challenges in the area of integrated circuit design in the United States for future High Energy Physics (HEP) experiments. It has been submitted to CPAD (Coordinating Panel for Advanced Detectors) and the HEP Community Summer Study 2013(Snowmass on the Mississippi) held in Minnesota July 29 to August 6, 2013. A workshop titled: US Workshop on IC Design for High Energy Physics, HEPIC2013 was held May 30 to June 1, 2013 at Lawrence Berkeley National Laboratory (LBNL). A draft of the whitepaper was distributed to the attendees before the workshop, the content was discussed at the meeting, and this document is the resulting final product. The scope of the whitepaper includes the following topics: Needs for IC technologies to enable future experiments in the three HEP frontiers Energy, Cosmic and Intensity Frontiers; Challenges in the different technology and circuit design areas and the related R&D needs; Motivation for using different fabrication technologies; Outlook of future technologies including 2.5D and 3D; Survey of ICs used in current experiments and ICs targeted for approved or proposed experiments; IC design at US institutes and recommendations for collaboration in the future.

  20. Development of high integrity containers for rad-waste treatment

    Energy Technology Data Exchange (ETDEWEB)

    Song, Yung Chul; Cho, Myung Sug; Jung, Yun Sub [Korea Electric Power Corp. (KEPCO), Taejon (Korea, Republic of). Research Center

    1995-12-31

    Nuclear power plants are generating rad waste such as solid wastes, concentrated liquid wastes, spent resins and spent filters, and various types of imported containers which have different specifications and material properties are employed to handle the rad wastes according to facility characteristics of the plants or the type of wastes. These containers are stored at the intermediate storage facilities at the plant site due to the construction delay of permanent disposal site, and the additional construction of storage and disposal sites become more difficult with increase of the numbers and the operation time of the plants. In order to solve these difficulties, rad wastes volume reduction facilities such as High Pressure Compression Facility or Drying Facility are being installed and use of High Integrity Containers(HIC) are increasing. Therefore, we decide quality and technology standards required for the HIC, and then develop the HIC which satisfies the standards with new composite material called Steel Fiber Polymer Impregnated Concrete(SFPIC) (author). 84 refs., 118 figs.

  1. An integrated CMOS high data rate transceiver for video applications

    International Nuclear Information System (INIS)

    Liang Yaping; Sun Lingling; Che Dazhi; Liang Cheng

    2012-01-01

    This paper presents a 5 GHz CMOS radio frequency (RF) transceiver built with 0.18 μm RF-CMOS technology by using a proprietary protocol, which combines the new IEEE 802.11n features such as multiple-in multiple-out (MIMO) technology with other wireless technologies to provide high data rate robust real-time high definition television (HDTV) distribution within a home environment. The RF frequencies cover from 4.9 to 5.9 GHz: the industrial, scientific and medical (ISM) band. Each RF channel bandwidth is 20 MHz. The transceiver utilizes a direct up transmitter and low-IF receiver architecture. A dual-quadrature direct up conversion mixer is used that achieves better than 35 dB image rejection without any on chip calibration. The measurement shows a 6 dB typical receiver noise figure and a better than 33 dB transmitter error vector magnitude (EVM) at −3 dBm output power. (semiconductor integrated circuits)

  2. Development of high integrity containers for rad-waste treatment

    Energy Technology Data Exchange (ETDEWEB)

    Song, Yung Chul; Cho, Myung Sug; Jung, Yun Sub [Korea Electric Power Corp. (KEPCO), Taejon (Korea, Republic of). Research Center

    1996-12-31

    Nuclear power plants are generating rad waste such as solid wastes, concentrated liquid wastes, spent resins and spent filters, and various types of imported containers which have different specifications and material properties are employed to handle the rad wastes according to facility characteristics of the plants or the type of wastes. These containers are stored at the intermediate storage facilities at the plant site due to the construction delay of permanent disposal site, and the additional construction of storage and disposal sites become more difficult with increase of the numbers and the operation time of the plants. In order to solve these difficulties, rad wastes volume reduction facilities such as High Pressure Compression Facility or Drying Facility are being installed and use of High Integrity Containers(HIC) are increasing. Therefore, we decide quality and technology standards required for the HIC, and then develop the HIC which satisfies the standards with new composite material called Steel Fiber Polymer Impregnated Concrete(SFPIC) (author). 84 refs., 118 figs.

  3. High temperature spectral emissivity measurement using integral blackbody method

    Science.gov (United States)

    Pan, Yijie; Dong, Wei; Lin, Hong; Yuan, Zundong; Bloembergen, Pieter

    2016-10-01

    Spectral emissivity is a critical material's thermos-physical property for heat design and radiation thermometry. A prototype instrument based upon an integral blackbody method was developed to measure material's spectral emissivity above 1000 °. The system was implemented with an optimized commercial variable-high-temperature blackbody, a high speed linear actuator, a linear pyrometer, and an in-house designed synchronization circuit. A sample was placed in a crucible at the bottom of the blackbody furnace, by which the sample and the tube formed a simulated blackbody which had an effective total emissivity greater than 0.985. During the measurement, the sample was pushed to the end opening of the tube by a graphite rod which was actuated through a pneumatic cylinder. A linear pyrometer was used to monitor the brightness temperature of the sample surface through the measurement. The corresponding opto-converted voltage signal was fed and recorded by a digital multi-meter. A physical model was proposed to numerically evaluate the temperature drop along the process. Tube was discretized as several isothermal cylindrical rings, and the temperature profile of the tube was measurement. View factors between sample and rings were calculated and updated along the whole pushing process. The actual surface temperature of the sample at the end opening was obtained. Taking advantages of the above measured voltage profile and the calculated true temperature, spectral emissivity under this temperature point was calculated.

  4. A High Integrity Can Design for Degraded Nuclear Fuel

    International Nuclear Information System (INIS)

    Holmes, P.A.

    1999-01-01

    A high integrity can (HIC), designed to meet the ASME Boiler and Pressure Vessel Code (Section III, Div. 3, static conditions) is proposed for the interim storage and repository disposal of Department of Energy (DOE) spent nuclear fuel. The HIC will be approximately 5 3/8 inches (134.38mm) in outside diameter with 1/4 inch (6.35mm) thick walls, and have a removable lid with a metallic seal that is capable of being welded shut. The opening of the can is approximately 4 3/8 inches (111.13mm). The HIC is primarily designed to contain items in the DOE SNF inventory that do not meet acceptance standards for direct disposal in a geologic repository. This includes fuel in the form of particulate dusts, sectioned pieces of fuel, core rubble, melted or degraded (non-intact) fuel elements, unclad uranium alloys, metallurgical specimens, and chemically reactive fuel components. The HIC is intended to act as a substitute cladding for the spent nuclear fuel, further isolate problematic materials, provide a long-term corrosion barrier, and add an extra internal pressure barrier to the waste package. The HIC will also delay potential fission product release and maintain geometry control for extended periods of time. For the entire disposal package to be licensed by the Nuclear Regulatory Commission, a HIC must effectively eliminate the disposal problems associated with problem SNF including the release of radioactive and/or reactive material and over pressurization of the HIC due to chemical reactions within the can. Two HICs were analyzed to envelop a range of can lengths between 42 and 101 inches. Using Abacus software, the HIC's were analyzed for end, side, and corner drops. Hastelloy C-22 was chosen based upon structural integrity, corrosion resistance, and neutron adsorption properties

  5. Integration Testing of a Modular Discharge Supply for NASA's High Voltage Hall Accelerator Thruster

    Science.gov (United States)

    Pinero, Luis R.; Kamhawi, hani; Drummond, Geoff

    2010-01-01

    NASA s In-Space Propulsion Technology Program is developing a high performance Hall thruster that can fulfill the needs of future Discovery-class missions. The result of this effort is the High Voltage Hall Accelerator thruster that can operate over a power range from 0.3 to 3.5 kW and a specific impulse from 1,000 to 2,800 sec, and process 300 kg of xenon propellant. Simultaneously, a 4.0 kW discharge power supply comprised of two parallel modules was developed. These power modules use an innovative three-phase resonant topology that can efficiently supply full power to the thruster at an output voltage range of 200 to 700 V at an input voltage range of 80 to 160 V. Efficiencies as high as 95.9 percent were measured during an integration test with the NASA103M.XL thruster. The accuracy of the master/slave current sharing circuit and various thruster ignition techniques were evaluated.

  6. An integrated framework for high level design of high performance signal processing circuits on FPGAs

    Science.gov (United States)

    Benkrid, K.; Belkacemi, S.; Sukhsawas, S.

    2005-06-01

    This paper proposes an integrated framework for the high level design of high performance signal processing algorithms' implementations on FPGAs. The framework emerged from a constant need to rapidly implement increasingly complicated algorithms on FPGAs while maintaining the high performance needed in many real time digital signal processing applications. This is particularly important for application developers who often rely on iterative and interactive development methodologies. The central idea behind the proposed framework is to dynamically integrate high performance structural hardware description languages with higher level hardware languages in other to help satisfy the dual requirement of high level design and high performance implementation. The paper illustrates this by integrating two environments: Celoxica's Handel-C language, and HIDE, a structural hardware environment developed at the Queen's University of Belfast. On the one hand, Handel-C has been proven to be very useful in the rapid design and prototyping of FPGA circuits, especially control intensive ones. On the other hand, HIDE, has been used extensively, and successfully, in the generation of highly optimised parameterisable FPGA cores. In this paper, this is illustrated in the construction of a scalable and fully parameterisable core for image algebra's five core neighbourhood operations, where fully floorplanned efficient FPGA configurations, in the form of EDIF netlists, are generated automatically for instances of the core. In the proposed combined framework, highly optimised data paths are invoked dynamically from within Handel-C, and are synthesized using HIDE. Although the idea might seem simple prima facie, it could have serious implications on the design of future generations of hardware description languages.

  7. Very high precision and accuracy analysis of triple isotopic ratios of water. A critical instrumentation comparison study.

    Science.gov (United States)

    Gkinis, Vasileios; Holme, Christian; Morris, Valerie; Thayer, Abigail Grace; Vaughn, Bruce; Kjaer, Helle Astrid; Vallelonga, Paul; Simonsen, Marius; Jensen, Camilla Marie; Svensson, Anders; Maffrezzoli, Niccolo; Vinther, Bo; Dallmayr, Remi

    2017-04-01

    We present a performance comparison study between two state of the art Cavity Ring Down Spectrometers (Picarro L2310-i, L2140-i). The comparison took place during the Continuous Flow Analysis (CFA) campaign for the measurement of the Renland ice core, over a period of three months. Instant and complete vaporisation of the ice core melt stream, as well as of in-house water reference materials is achieved by accurate control of microflows of liquid into a homemade calibration system by following simple principles of the Hagen-Poiseuille law. Both instruments share the same vaporisation unit in a configuration that minimises sample preparation discrepancies between the two analyses. We describe our SMOW-SLAP calibration and measurement protocols for such a CFA application and present quality control metrics acquired during the full period of the campaign on a daily basis. The results indicate an unprecedented performance for all 3 isotopic ratios (δ2H, δ17O, δ18O ) in terms of precision, accuracy and resolution. We also comment on the precision and accuracy of the second order excess parameters of HD16O and H217O over H218O (Dxs, Δ17O ). To our knowledge these are the first reported CFA measurements at this level of precision and accuracy for all three isotopic ratios. Differences on the performance of the two instruments are carefully assessed during the measurement and reported here. Our quality control protocols extend to the area of low water mixing ratios, a regime in which often atmospheric vapour measurements take place and Cavity Ring Down Analysers show a poorer performance due to the lower signal to noise ratios. We address such issues and propose calibration protocols from which water vapour isotopic analyses can benefit from.

  8. Mildronate (Meldonium) in professional sports - monitoring doping control urine samples using hydrophilic interaction liquid chromatography - high resolution/high accuracy mass spectrometry.

    Science.gov (United States)

    Görgens, Christian; Guddat, Sven; Dib, Josef; Geyer, Hans; Schänzer, Wilhelm; Thevis, Mario

    2015-01-01

    To date, substances such as Mildronate (Meldonium) are not on the radar of anti-doping laboratories as the compound is not explicitly classified as prohibited. However, the anti-ischemic drug Mildronate demonstrates an increase in endurance performance of athletes, improved rehabilitation after exercise, protection against stress, and enhanced activations of central nervous system (CNS) functions. In the present study, the existing evidence of Mildronate's usage in sport, which is arguably not (exclusively) based on medicinal reasons, is corroborated by unequivocal analytical data allowing the estimation of the prevalence and extent of misuse in professional sports. Such data are vital to support decision-making processes, particularly regarding the ban on drugs in sport. Due to the growing body of evidence (black market products and athlete statements) concerning its misuse in sport, adequate test methods for the reliable identification of Mildronate are required, especially since the substance has been added to the 2015 World Anti-Doping Agency (WADA) monitoring program. In the present study, two approaches were established using an in-house synthesized labelled internal standard (Mildronate-D3 ). One aimed at the implementation of the analyte into routine doping control screening methods to enable its monitoring at the lowest possible additional workload for the laboratory, and another that is appropriate for the peculiar specifics of the analyte, allowing the unequivocal confirmation of findings using hydrophilic interaction liquid chromatography-high resolution/high accuracy mass spectrometry (HILIC-HRMS). Here, according to applicable regulations in sports drug testing, a full qualitative validation was conducted. The assay demonstrated good specificity, robustness (rRT=0.3%), precision (intra-day: 7.0-8.4%; inter-day: 9.9-12.9%), excellent linearity (R>0.99) and an adequate lower limit of detection (<10 ng/mL). Copyright © 2015 John Wiley & Sons, Ltd.

  9. Mildronate (Meldonium) in professional sports – monitoring doping control urine samples using hydrophilic interaction liquid chromatography – high resolution/high accuracy mass spectrometry

    Science.gov (United States)

    Görgens, Christian; Dib, Josef; Geyer, Hans; Schänzer, Wilhelm; Thevis, Mario

    2015-01-01

    To date, substances such as Mildronate (Meldonium) are not on the radar of anti‐doping laboratories as the compound is not explicitly classified as prohibited. However, the anti‐ischemic drug Mildronate demonstrates an increase in endurance performance of athletes, improved rehabilitation after exercise, protection against stress, and enhanced activations of central nervous system (CNS) functions. In the present study, the existing evidence of Mildronate's usage in sport, which is arguably not (exclusively) based on medicinal reasons, is corroborated by unequivocal analytical data allowing the estimation of the prevalence and extent of misuse in professional sports. Such data are vital to support decision‐making processes, particularly regarding the ban on drugs in sport. Due to the growing body of evidence (black market products and athlete statements) concerning its misuse in sport, adequate test methods for the reliable identification of Mildronate are required, especially since the substance has been added to the 2015 World Anti‐Doping Agency (WADA) monitoring program. In the present study, two approaches were established using an in‐house synthesized labelled internal standard (Mildronate‐D3). One aimed at the implementation of the analyte into routine doping control screening methods to enable its monitoring at the lowest possible additional workload for the laboratory, and another that is appropriate for the peculiar specifics of the analyte, allowing the unequivocal confirmation of findings using hydrophilic interaction liquid chromatography‐high resolution/high accuracy mass spectrometry (HILIC‐HRMS). Here, according to applicable regulations in sports drug testing, a full qualitative validation was conducted. The assay demonstrated good specificity, robustness (rRT=0.3%), precision (intra‐day: 7.0–8.4%; inter‐day: 9.9–12.9%), excellent linearity (R>0.99) and an adequate lower limit of detection (<10 ng/mL). © 2015 The Authors

  10. Integral-preserving integrators

    International Nuclear Information System (INIS)

    McLaren, D I; Quispel, G R W

    2004-01-01

    Ordinary differential equations having a first integral may be solved numerically using one of several methods, with the integral preserved to machine accuracy. One such method is the discrete gradient method. It is shown here that the order of the method can be bootstrapped repeatedly to higher orders of accuracy. The method is illustrated using the Henon-Heiles system. (letter to the editor)

  11. Integrative Medicine Patients Have High Stress, Pain, and Psychological Symptoms.

    Science.gov (United States)

    Wolever, Ruth Q; Goel, Nikita S; Roberts, Rhonda S; Caldwell, Karen; Kligler, Benjamin; Dusek, Jeffery A; Perlman, Adam; Dolor, Rowena; Abrams, Donald I

    2015-01-01

    Integrative medicine (IM) is a rapidly growing field whose providers report clinical success in treating significant stress, chronic pain, and depressive and anxiety symptoms. While IM therapies have demonstrated efficacy for numerous medical conditions, IM for psychological symptoms has been slower to gain recognition in the medical community. This large, cross-sectional study is the first of its kind to document the psychosocial profiles of 4182 patients at 9 IM clinics that form the BraveNet Practice-Based Research Network (PBRN). IM patients reported higher levels of perceived stress, pain, and depressive symptoms, and lower levels of quality of life compared with national norms. Per provider reports, 60% of patients had at least one of the following: stress (9.3%), fatigue (10.2%), anxiety (7.7%), depression (7.2%), and/or sleep disorders (4.8%). Pain, having both physiological and psychological components, was also included and is the most common condition treated at IM clinics. Those with high stress, psychological conditions, and pain were most frequently treated with acupuncture, IM physician consultation, exercise, chiropractic services, diet/nutrition counseling, and massage. With baseline information on clinical presentation and service utilization, future PBRN studies can examine promising interventions delivered at the clinic to treat stress and psychological conditions. Copyright © 2015 Elsevier Inc. All rights reserved.