WorldWideScience

Sample records for high accuracy critical-angle

  1. Device for Measuring Landslide Critical Angle

    Institute of Scientific and Technical Information of China (English)

    Li Xueling; Xia Weisheng; Huang Daoyou; Yu Yun

    2016-01-01

    The mountain landslide has high destructive effects, discussion of its landslide critical angle has always been one of the major concerns, and we designed a system that can automatically measure the landslide critical angle. This equipment consists of the

  2. Algorithms of wave reflective critical angle on interface

    Science.gov (United States)

    Zhang, YongGang; Zhang, JianXue; Jiao, Lin; Li, Qinghong

    2017-02-01

    This article is in connection with calculating of reflection critical angle on interface, author has found that reflective wave have a quarter wavelength effects and deduced both absolute and relative reflection critical Angle calculation formulas. The two formulas can easy solve the question of reflection critical angle on interface of one side of the air where it is not calculated by Snell's law. Snell's law only reveals that rate of the wave velocity projected to the interface, the methods of this paper reveal the normal component of wave velocity on the interface relationship. The methods will be widely used in various fields such as light, electromagnetic waves, sound waves and water waves etc.

  3. High accuracy flexural hinge development

    Science.gov (United States)

    Santos, I.; Ortiz de Zárate, I.; Migliorero, G.

    2005-07-01

    This document provides a synthesis of the technical results obtained in the frame of the HAFHA (High Accuracy Flexural Hinge Assembly) development performed by SENER (in charge of design, development, manufacturing and testing at component and mechanism levels) with EADS Astrium as subcontractor (in charge of doing an inventory of candidate applications among existing and emerging projects, establishing the requirements and perform system level testing) under ESA contract. The purpose of this project has been to develop a competitive technology for a flexural pivot, usuable in highly accurate and dynamic pointing/scanning mechanisms. Compared with other solutions (e.g. magnetic or ball bearing technologies) flexural hinges are the appropriate technology for guiding with accuracy a mobile payload over a limited angular ranges around one rotation axes.

  4. High Accuracy Imaging Polarimetry with NICMOS

    CERN Document Server

    Batcheldor, D; Hines, D C; Schmidt, G D; Axon, D J; Robinson, A; Sparks, W; Tadhunter, C

    2008-01-01

    The ability of NICMOS to perform high accuracy polarimetry is currently hampered by an uncalibrated residual instrumental polarization at a level of 1.2-1.5%. To better quantify and characterize this residual we obtained observations of three polarimetric standard stars at three separate space-craft roll angles. Combined with archival data, these observations were used to characterize the residual instrumental polarization to enable NICMOS to reach its full polarimetric potential. Using these data, we calculate values of the parallel transmission coefficients that reproduce the ground-based results for the polarimetric standards. The uncertainties associated with the parallel transmission coefficients, a result of the photometric repeatability of the observations, dominate the accuracy of p and theta. However, the new coefficients now enable imaging polarimetry of targets with p~1.0% at an accuracy of +/-0.6% and +/-15 degrees.

  5. High accuracy FIONA-AFM hybrid imaging.

    Science.gov (United States)

    Fronczek, D N; Quammen, C; Wang, H; Kisker, C; Superfine, R; Taylor, R; Erie, D A; Tessmer, I

    2011-04-01

    Multi-protein complexes are ubiquitous and play essential roles in many biological mechanisms. Single molecule imaging techniques such as electron microscopy (EM) and atomic force microscopy (AFM) are powerful methods for characterizing the structural properties of multi-protein and multi-protein-DNA complexes. However, a significant limitation to these techniques is the ability to distinguish different proteins from one another. Here, we combine high resolution fluorescence microscopy and AFM (FIONA-AFM) to allow the identification of different proteins in such complexes. Using quantum dots as fiducial markers in addition to fluorescently labeled proteins, we are able to align fluorescence and AFM information to ≥8nm accuracy. This accuracy is sufficient to identify individual fluorescently labeled proteins in most multi-protein complexes. We investigate the limitations of localization precision and accuracy in fluorescence and AFM images separately and their effects on the overall registration accuracy of FIONA-AFM hybrid images. This combination of the two orthogonal techniques (FIONA and AFM) opens a wide spectrum of possible applications to the study of protein interactions, because AFM can yield high resolution (5-10nm) information about the conformational properties of multi-protein complexes and the fluorescence can indicate spatial relationships of the proteins in the complexes.

  6. High Accuracy Transistor Compact Model Calibrations

    Energy Technology Data Exchange (ETDEWEB)

    Hembree, Charles E. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Mar, Alan [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Robertson, Perry J. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)

    2015-09-01

    Typically, transistors are modeled by the application of calibrated nominal and range models. These models consists of differing parameter values that describe the location and the upper and lower limits of a distribution of some transistor characteristic such as current capacity. Correspond- ingly, when using this approach, high degrees of accuracy of the transistor models are not expected since the set of models is a surrogate for a statistical description of the devices. The use of these types of models describes expected performances considering the extremes of process or transistor deviations. In contrast, circuits that have very stringent accuracy requirements require modeling techniques with higher accuracy. Since these accurate models have low error in transistor descriptions, these models can be used to describe part to part variations as well as an accurate description of a single circuit instance. Thus, models that meet these stipulations also enable the calculation of quantifi- cation of margins with respect to a functional threshold and uncertainties in these margins. Given this need, new model high accuracy calibration techniques for bipolar junction transis- tors have been developed and are described in this report.

  7. High accuracy 3-D laser radar

    DEFF Research Database (Denmark)

    Busck, Jens; Heiselberg, Henning

    2004-01-01

    We have developed a mono-static staring 3-D laser radar based on gated viewing with range accuracy below 1 m at 10 m and 1 cm at 100. We use a high sensitivity, fast, intensified CCD camera, and a Nd:Yag passively Q-switched 32.4 kHz pulsed green laser at 532 nm. The CCD has 752x582 pixels. Camera...

  8. Computing High Accuracy Power Spectra with Pico

    CERN Document Server

    Fendt, William A

    2007-01-01

    This paper presents the second release of Pico (Parameters for the Impatient COsmologist). Pico is a general purpose machine learning code which we have applied to computing the CMB power spectra and the WMAP likelihood. For this release, we have made improvements to the algorithm as well as the data sets used to train Pico, leading to a significant improvement in accuracy. For the 9 parameter nonflat case presented here Pico can on average compute the TT, TE and EE spectra to better than 1% of cosmic standard deviation for nearly all $\\ell$ values over a large region of parameter space. Performing a cosmological parameter analysis of current CMB and large scale structure data, we show that these power spectra give very accurate 1 and 2 dimensional parameter posteriors. We have extended Pico to allow computation of the tensor power spectrum and the matter transfer function. Pico runs about 1500 times faster than CAMB at the default accuracy and about 250,000 times faster at high accuracy. Training Pico can be...

  9. Fast and High Accuracy Wire Scanner

    CERN Document Server

    Koujili, M; Koopman, J; Ramos, D; Sapinski, M; De Freitas, J; Ait Amira, Y; Djerdir, A

    2009-01-01

    Scanning of a high intensity particle beam imposes challenging requirements on a Wire Scanner system. It is expected to reach a scanning speed of 20 m.s-1 with a position accuracy of the order of 1 μm. In addition a timing accuracy better than 1 millisecond is needed. The adopted solution consists of a fork holding a wire rotating by a maximum of 200°. Fork, rotor and angular position sensor are mounted on the same axis and located in a chamber connected to the beam vacuum. The requirements imply the design of a system with extremely low vibration, vacuum compatibility, radiation and temperature tolerance. The adopted solution consists of a rotary brushless synchronous motor with the permanent magnet rotor installed inside of the vacuum chamber and the stator installed outside. The accurate position sensor will be mounted on the rotary shaft inside of the vacuum chamber, has to resist a bake-out temperature of 200°C and ionizing radiation up to a dozen of kGy/year. A digital feedback controller allows maxi...

  10. High accuracy 3-D laser radar

    DEFF Research Database (Denmark)

    Busck, Jens; Heiselberg, Henning

    2004-01-01

    We have developed a mono-static staring 3-D laser radar based on gated viewing with range accuracy below 1 m at 10 m and 1 cm at 100. We use a high sensitivity, fast, intensified CCD camera, and a Nd:Yag passively Q-switched 32.4 kHz pulsed green laser at 532 nm. The CCD has 752x582 pixels. Camera...... shutter is controlled in steps of 100 ps. Camera delay is controlled in steps of 100 ps. Each laser pulse triggers the camera delay and shutter. A 3-D image is constructed from a sequence of 50-100 2-D reflectivity images, where each frame integrates about 700 laser pulses on the CCD. In 50 Hz video mode...

  11. A SINGLE STEP SCHEME WITH HIGH ACCURACY FOR PARABOLIC PROBLEM

    Institute of Scientific and Technical Information of China (English)

    陈传淼; 胡志刚

    2001-01-01

    A single step scheme with high accuracy for solving parabolic problem is proposed. It is shown that this scheme possesses good stability and fourth order accuracy with respect to both time and space variables, which are superconvergent.

  12. Determination of uranium and thorium contents inside different materials using track detectors and mean critical angles

    CERN Document Server

    Misdaq, M A; Ktata, A; Merzouki, A; Youbi, N

    1999-01-01

    The critical angles of the CR-39 (theta sub c) and LR-115 type II (theta sub c ') solid state nuclear track detectors (SSNTD) for detecting alpha-particles emitted by the uranium and thorium series have been evaluated by calculating the corresponding ranges of the emitted alpha-particles in different material samples and in the SSNTD studied. The influence of the emitted alpha-particles initial and residual energies on the critical angles of the SSNTD studied has been investigated. The uranium and thorium contents of different geological samples have been evaluated by exploiting data obtained for the critical angles of the CR-39 and LR-115 type II solid state nuclear track detectors and measuring the corresponding densities of tracks.

  13. Methodology for high accuracy contact angle measurement.

    Science.gov (United States)

    Kalantarian, A; David, R; Neumann, A W

    2009-12-15

    A new version of axisymmetric drop shape analysis (ADSA) called ADSA-NA (ADSA-no apex) was developed for measuring interfacial properties for drop configurations without an apex. ADSA-NA facilitates contact angle measurements on drops with a capillary protruding into the drop. Thus a much simpler experimental setup, not involving formation of a complete drop from below through a hole in the test surface, may be used. The contact angles of long-chained alkanes on a commercial fluoropolymer, Teflon AF 1600, were measured using the new method. A new numerical scheme was incorporated into the image processing to improve the location of the contact points of the liquid meniscus with the solid substrate to subpixel resolution. The images acquired in the experiments were also analyzed by a different drop shape technique called theoretical image fitting analysis-axisymmetric interfaces (TIFA-AI). The results were compared with literature values obtained by means of the standard ADSA for sessile drops with the apex. Comparison of the results from ADSA-NA with those from TIFA-AI and ADSA reveals that, with different numerical strategies and experimental setups, contact angles can be measured with an accuracy of less than 0.2 degrees. Contact angles and surface tensions measured from drops with no apex, i.e., by means of ADSA-NA and TIFA-AI, were considerably less scattered than those from complete drops with apex. ADSA-NA was also used to explore sources of improvement in contact angle resolution. It was found that using an accurate value of surface tension as an input enhances the accuracy of contact angle measurements.

  14. Characterization of surface Ag nanoparticles in nanocomposite a-C:Ag coatings by grazing incidence X-ray diffraction at sub-critical angles of incidence

    Energy Technology Data Exchange (ETDEWEB)

    Manninen, N.K.; Oliveira, J.C.; Cavaleiro, A. [University of Coimbra, SEG-CEMUC, Mechanical Engineering Department, Coimbra (Portugal); Carvalho, S. [University of Minho, GRF-CFUM, Physics Department, Guimaraes (Portugal)

    2016-03-15

    Silver diffusion within nanocomposite films and/or toward the film surface is often observed during annealing of the silver-based nanocomposite films. In order to control and/or minimize this process, it is crucial to characterize the aggregated silver nanoparticles on the films surface. In this paper grazing incidence X-ray diffraction (GIXRD) with both sub-critical and supra-critical angles of incidence is used to characterize the Ag nanoparticles distribution, shape and structure both inside the matrix and on the nanocomposite film surface. The nanocomposite carbon coating containing Ag nanoparticles (a-C:Ag) was deposited by dc magnetron sputtering. The coatings were analyzed by GIXRD using fixed incident angles both below and above the critical angle for total reflection. By using sub-critical angles it was possible to eliminate diffraction from the bulk material allowing to estimate the size distribution of the nanoparticles sitting on the surface. The results obtained by GIXRD analysis were checked through comparison with the observations made by both TEM and SEM analysis. The proposed methodology can be used to characterized nanoparticles deposition on a surface and/or island formation during film growth as long an adequate substrate with high critical angle for total reflection is used. (orig.)

  15. High accuracy GNSS based navigation in GEO

    Science.gov (United States)

    Capuano, Vincenzo; Shehaj, Endrit; Blunt, Paul; Botteron, Cyril; Farine, Pierre-André

    2017-07-01

    Although significant improvements in efficiency and performance of communication satellites have been achieved in the past decades, it is expected that the demand for new platforms in Geostationary Orbit (GEO) and for the On-Orbit Servicing (OOS) on the existing ones will continue to rise. Indeed, the GEO orbit is used for many applications including direct broadcast as well as communications. At the same time, Global Navigation Satellites System (GNSS), originally designed for land, maritime and air applications, has been successfully used as navigation system in Low Earth Orbit (LEO) and its further utilization for navigation of geosynchronous satellites becomes a viable alternative offering many advantages over present ground based methods. Following our previous studies of GNSS signal characteristics in Medium Earth Orbit (MEO), GEO and beyond, in this research we specifically investigate the processing of different GNSS signals, with the goal to determine the best navigation performance they can provide in a GEO mission. Firstly, a detailed selection among different GNSS signals and different combinations of them is discussed, taking into consideration the L1 and L5 frequency bands, and the GPS and Galileo constellations. Then, the implementation of an Orbital Filter is summarized, which adaptively fuses the GN1SS observations with an accurate orbital forces model. Finally, simulation tests of the navigation performance achievable by processing the selected combination of GNSS signals are carried out. The results obtained show an achievable positioning accuracy of less than one meter. In addition, hardware-in-the-loop tests are presented using a COTS receiver connected to our GNSS Spirent simulator, in order to collect real-time hardware-in-the-loop observations and process them by the proposed navigation module.

  16. Compact, High Accuracy CO2 Monitor Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This Small Business Innovative Research Phase II proposal seeks to develop a low cost, robust, highly precise and accurate CO2 monitoring system. This system will...

  17. Compact, High Accuracy CO2 Monitor Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This Small Business Innovative Research Phase I proposal seeks to develop a low cost, robust, highly precise and accurate CO2 monitoring system. This system will...

  18. High speed high dynamic range high accuracy measurement system

    Energy Technology Data Exchange (ETDEWEB)

    Deibele, Craig E.; Curry, Douglas E.; Dickson, Richard W.; Xie, Zaipeng

    2016-11-29

    A measuring system includes an input that emulates a bandpass filter with no signal reflections. A directional coupler connected to the input passes the filtered input to electrically isolated measuring circuits. Each of the measuring circuits includes an amplifier that amplifies the signal through logarithmic functions. The output of the measuring system is an accurate high dynamic range measurement.

  19. Tilting of the magnetic field in Majorana nanowires: Critical angle and zero-energy differential conductance

    Science.gov (United States)

    Rex, Stefan; Sudbø, Asle

    2014-09-01

    Semiconductor nanowires with strong spin-orbit coupling and proximity-induced s-wave superconductivity in an external magnetic field have been the most promising settings for approaches towards experimental evidence of topological Majorana zero modes. We investigate the effect of tilting the magnetic field relative to the spin-orbit coupling direction in a simple continuum model and provide an analytical derivation of the critical angle, at which the topological states disappear. We also obtain the differential conductance characteristic of a junction with a normal wire for different tilting angles and propose a qualitative change of the dependence of the zero-energy differential conductance on the tunnel barrier strength at the critical angle as a criterion for establishing the topological nature of the observed signal.

  20. Optical characterization of bubbly flows with a near-critical-angle scattering technique

    Energy Technology Data Exchange (ETDEWEB)

    Onofri, Fabrice R.A.; Krzysiek, Mariusz [IUSTI, UMR, CNRS, University of Provence, Polytech' DME, Technopole Chateau-Gombert, Marseille (France); Mroczka, Janusz [CEPM, Technical University of Wroclaw, Wroclaw (Poland); Ren, Kuan-Fang [CORIA, UMR, CNRS, University of Rouen, Saint-Etienne-du-Rouvray (France); Radev, Stefan [IMECH, Bulgarian Academy of Sciences, Sofia (Bulgaria); Bonnet, Jean-Philippe [M2P2, UMR, CNRS, University Paul Cezanne, Aix-en-Provence (France)

    2009-10-15

    The newly developed critical angle refractometry and sizing technique (CARS) allows simultaneous and instantaneous characterization of the local size distribution and the relative refractive index (i.e. composition) of a cloud of bubbles. The paper presents the recent improvement of this technique by comparison of different light scattering models and inversion procedures. Experimental results carried in various air/water and air/water-ethanol bubbly flows clearly demonstrate the efficiency and the potential of this technique. (orig.)

  1. High accuracy in silico sulfotransferase models.

    Science.gov (United States)

    Cook, Ian; Wang, Ting; Falany, Charles N; Leyh, Thomas S

    2013-11-29

    Predicting enzymatic behavior in silico is an integral part of our efforts to understand biology. Hundreds of millions of compounds lie in targeted in silico libraries waiting for their metabolic potential to be discovered. In silico "enzymes" capable of accurately determining whether compounds can inhibit or react is often the missing piece in this endeavor. This problem has now been solved for the cytosolic sulfotransferases (SULTs). SULTs regulate the bioactivities of thousands of compounds--endogenous metabolites, drugs and other xenobiotics--by transferring the sulfuryl moiety (SO3) from 3'-phosphoadenosine 5'-phosphosulfate to the hydroxyls and primary amines of these acceptors. SULT1A1 and 2A1 catalyze the majority of sulfation that occurs during human Phase II metabolism. Here, recent insights into the structure and dynamics of SULT binding and reactivity are incorporated into in silico models of 1A1 and 2A1 that are used to identify substrates and inhibitors in a structurally diverse set of 1,455 high value compounds: the FDA-approved small molecule drugs. The SULT1A1 models predict 76 substrates. Of these, 53 were known substrates. Of the remaining 23, 21 were tested, and all were sulfated. The SULT2A1 models predict 22 substrates, 14 of which are known substrates. Of the remaining 8, 4 were tested, and all are substrates. The models proved to be 100% accurate in identifying substrates and made no false predictions at Kd thresholds of 100 μM. In total, 23 "new" drug substrates were identified, and new linkages to drug inhibitors are predicted. It now appears to be possible to accurately predict Phase II sulfonation in silico.

  2. High accuracy & long timescale light curves

    Directory of Open Access Journals (Sweden)

    Hodgkin S.

    2013-04-01

    Full Text Available We present a theoretical analysis of the optical light curves (LCs for short-period high-mass transiting extrasolar planet systems. Our method considers the primary transit, the secondary eclipse, and the overall phase shape of the LC between the occultations. Phase variations arise from (i reflected and thermally emitted light by the planet, (ii the ellipsoidal shape of the star due to the gravitational pull of the planet, and (iii the Doppler shift of the stellar light as the star orbits the center of mass of the system. Our full model of the out-of-eclipse variations contains information about the planetary mass, orbital eccentricity, the orientation of periastron and the planet's albedo. For a range of hypothetical systems we demonstrate that the ellipsoidal variations (ii. can be large enough to be distinguished from the remaining components and that this effect can be used to constrain the planet's mass. As an example we presend KOI-13b (candidate exoplanet system included in the September 2011 Kepler data release. The Kepler light curve shows both primary and secondary eclipses, as well as significant out-of-eclipse light curve variations. We model the relative contributions from (i thermal emission from the companion, (ii planetary reflected light, (iii doppler beaming, and (iv ellipsoidal variations in the host-star arising from the tidal distortion of the host star by its companion. Our analysis, based on the light curve alone, enables us to constrain the mass of the KOI-13.01 companion to be MC = 8.3 ± 1.25 MJ and thus demonstrates that the transiting companion is a planet. The teqnique is useful for current and future space missions such as Kepler and PLATO.

  3. High accuracy autonomous navigation using the global positioning system (GPS)

    Science.gov (United States)

    Truong, Son H.; Hart, Roger C.; Shoan, Wendy C.; Wood, Terri; Long, Anne C.; Oza, Dipak H.; Lee, Taesul

    1997-01-01

    The application of global positioning system (GPS) technology to the improvement of the accuracy and economy of spacecraft navigation, is reported. High-accuracy autonomous navigation algorithms are currently being qualified in conjunction with the GPS attitude determination flyer (GADFLY) experiment for the small satellite technology initiative Lewis spacecraft. Preflight performance assessments indicated that these algorithms are able to provide a real time total position accuracy of better than 10 m and a velocity accuracy of better than 0.01 m/s, with selective availability at typical levels. It is expected that the position accuracy will be increased to 2 m if corrections are provided by the GPS wide area augmentation system.

  4. Systematic Calibration for Ultra-High Accuracy Inertial Measurement Units.

    Science.gov (United States)

    Cai, Qingzhong; Yang, Gongliu; Song, Ningfang; Liu, Yiliang

    2016-06-22

    An inertial navigation system (INS) has been widely used in challenging GPS environments. With the rapid development of modern physics, an atomic gyroscope will come into use in the near future with a predicted accuracy of 5 × 10(-6)°/h or better. However, existing calibration methods and devices can not satisfy the accuracy requirements of future ultra-high accuracy inertial sensors. In this paper, an improved calibration model is established by introducing gyro g-sensitivity errors, accelerometer cross-coupling errors and lever arm errors. A systematic calibration method is proposed based on a 51-state Kalman filter and smoother. Simulation results show that the proposed calibration method can realize the estimation of all the parameters using a common dual-axis turntable. Laboratory and sailing tests prove that the position accuracy in a five-day inertial navigation can be improved about 8% by the proposed calibration method. The accuracy can be improved at least 20% when the position accuracy of the atomic gyro INS can reach a level of 0.1 nautical miles/5 d. Compared with the existing calibration methods, the proposed method, with more error sources and high order small error parameters calibrated for ultra-high accuracy inertial measurement units (IMUs) using common turntables, has a great application potential in future atomic gyro INSs.

  5. Systematic Calibration for Ultra-High Accuracy Inertial Measurement Units

    Directory of Open Access Journals (Sweden)

    Qingzhong Cai

    2016-06-01

    Full Text Available An inertial navigation system (INS has been widely used in challenging GPS environments. With the rapid development of modern physics, an atomic gyroscope will come into use in the near future with a predicted accuracy of 5 × 10−6°/h or better. However, existing calibration methods and devices can not satisfy the accuracy requirements of future ultra-high accuracy inertial sensors. In this paper, an improved calibration model is established by introducing gyro g-sensitivity errors, accelerometer cross-coupling errors and lever arm errors. A systematic calibration method is proposed based on a 51-state Kalman filter and smoother. Simulation results show that the proposed calibration method can realize the estimation of all the parameters using a common dual-axis turntable. Laboratory and sailing tests prove that the position accuracy in a five-day inertial navigation can be improved about 8% by the proposed calibration method. The accuracy can be improved at least 20% when the position accuracy of the atomic gyro INS can reach a level of 0.1 nautical miles/5 d. Compared with the existing calibration methods, the proposed method, with more error sources and high order small error parameters calibrated for ultra-high accuracy inertial measurement units (IMUs using common turntables, has a great application potential in future atomic gyro INSs.

  6. Refinement of the critical angle calculation for the contrast reversal of oil slicks under sunglint

    Science.gov (United States)

    Lu, Yingcheng; Sun, Shaojie; Zhang, Minwei; Murch, Brock; Hu, Chuanmin

    2016-01-01

    It has long been observed that oil slicks under sunglint can reverse their optical contrast against nearby oil-free seawater. Such a phenomenon has been described through both empirical statistical analysis of the sunglint strength and modeled theoretically using a critical angle concept. The critical angle, in this model, is the angle at which the image pixels show no or negligible contrast between oiled and nonoiled seawater. Pixels away from this critical angle show either positive or negative contrast from the oil-free pixels. Although this concept has been fully demonstrated in the published literature, its calculation needs to be further refined to take into account: (1) the different refractive indices of oil slicks (from natural seeps) and seawater and (2) atmospheric effects in the sensor-measured radiance. Using measurements from the Moderate Resolution Imaging Spectroradiometer (MODIS) over oil films in the Gulf of Mexico, we show improvement in the modeled and MODIS-derived reflectance over oil slicks originated from natural seeps after incorporating these two factors in the model. Specifically, agreement between modeled and measured sunglint reflectance is found for both negative and positive-contrasting oil slicks. These results indicate that surface roughness and reflectance from oil films can be estimated given any solar/viewing geometry and surface wind. Further, this model might be used to correct the sunglint effect on thick oil under similar illumination conditions. Once proven possible, it may allow existing laboratory-based models, which estimate oil thickness after such corrections, to be applied to remote sensing imagery.

  7. High Accuracy Wavelength Calibration For A Scanning Visible Spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Filippo Scotti and Ronald Bell

    2010-07-29

    Spectroscopic applications for plasma velocity measurements often require wavelength accuracies ≤ 0.2Â. An automated calibration for a scanning spectrometer has been developed to achieve a high wavelength accuracy overr the visible spectrum, stable over time and environmental conditions, without the need to recalibrate after each grating movement. The method fits all relevant spectrometer paraameters using multiple calibration spectra. With a steping-motor controlled sine-drive, accuracies of ~0.025 Â have been demonstrated. With the addition of high resolution (0.075 aresec) optical encoder on the grading stage, greater precision (~0.005 Â) is possible, allowing absolute velocity measurements with ~0.3 km/s. This level of precision requires monitoring of atmospheric temperature and pressure and of grating bulk temperature to correct for changes in the refractive index of air and the groove density, respectively.

  8. Influence of spatial temperature distribution on high accuracy interferometric metrology

    Science.gov (United States)

    Gu, Yongqiang; Miao, Erlong; Yan, Feng; Zhang, Jian; Yang, Huaijiang

    2010-10-01

    We calculate the influence of temperature change on the refractive index of air, establish a model of air temperature distribution and analyze the effect of different temperature distribution on the high accuracy interferometric metrology. First, a revised Edlen formula is employed to acquire the relation between temperature and refractive index of air, followed by introducing the fixed temperature gradient distribution among the spatial grid within the optical cavity between the reference flat and the test flat of the Fizeau interferometer, accompanied by a temperature change random function within each grid. Finally, all the rays through the air layer with different incident angles are traced by Matlab program in order to obtain the final output position, angle and OPD for each ray. The influence of different temperature distribution and the length of the optical cavity in on the testing accuracy can be analyzed through the RMS value that results from repeatable rays tracing. As a result, the horizontal distribution (vertical to optical axis) has a large effect on the testing accuracy. Thus, to realize the high accuracy figure metrology, the horizontal distribution of temperature must be rigorously controlled as well as to shorten the length of the optical cavity to a large extent. The results from our simulation are of great significant for the accuracy analysis of interferometric testing and the research of manufacturing a interferometer.

  9. Critical-angle x-ray transmission grating spectrometer with extended bandpass and resolving power > 10,000

    CERN Document Server

    Heilmann, Ralf K; Kolodziejczak, Jeffery; Gaskin, Jessica A; O'Dell, Stephen L; Bhatia, Ritwik; Schattenburg, Mark L

    2016-01-01

    Several high priority subjects in astrophysics can be addressed by a state-of-the-art soft x-ray grating spectrometer (XGS). An Explorer-scale, large-area (> 1,000 cm2), high resolving power (R > 3,000) XGS is highly feasible based on Critical-Angle Transmission (CAT) gratings, even for telescopes with angular resolution of 5-10 arcsec. Significantly higher performance can be provided by a CAT XGS on an X-ray-Surveyor-type mission. CAT gratings combine the advantages of blazed reflection gratings (high efficiency, use of higher diffraction orders) with those of transmission gratings (low mass, relaxed alignment and temperature requirements, transparent at high energies) with minimal mission resource demands. They are high-efficiency blazed transmission gratings that consist of freestanding, ultra-high aspect-ratio grating bars made from SOI wafers using anisotropic dry and wet etch techniques. Blazing is achieved through reflection off grating bar sidewalls. Silicon is well matched to the soft x-ray band, and...

  10. DIPSY, a low-cost GPS application with high accuracy

    NARCIS (Netherlands)

    Heijden, W.F.M. van der

    1998-01-01

    To improve the control of unmanned aircraft flying out of visual range, the controller needs to be provided with realtime information about the position and behaviour of the drone during the flight. The position of the drone has to be presented with a relative high accuracy to obtain accurate flight

  11. DIPSY, a low-cost GPS application with high accuracy

    NARCIS (Netherlands)

    Heijden, W.F.M. van der

    1999-01-01

    To improve the control of unmanned aircraft flying out of visual range, the controller needs to be provided with real-time information about the position and behaviour of the drone during the flight. The position of the drone has to be presented with a relative high accuracy to obtain accurate lligh

  12. DIPSY, a low-cost GPS application with high accuracy

    NARCIS (Netherlands)

    Heijden, W.F.M. van der

    1999-01-01

    To improve the control of unmanned aircraft flying out of visual range, the controller needs to be provided with real-time information about the position and behaviour of the drone during the flight. The position of the drone has to be presented with a relative high accuracy to obtain accurate lligh

  13. DIPSY, a low-cost GPS application with high accuracy

    NARCIS (Netherlands)

    Heijden, W.F.M. van der

    1998-01-01

    To improve the control of unmanned aircraft flying out of visual range, the controller needs to be provided with realtime information about the position and behaviour of the drone during the flight. The position of the drone has to be presented with a relative high accuracy to obtain accurate flight

  14. DIPSY, a low-cost GPS application with high accuracy

    NARCIS (Netherlands)

    Heijden, W.F.M. van der

    1999-01-01

    To improve the control of unmanned aircraft flying out of visual range, the controller needs to be provided with real-time information about the position and behaviour of the drone during the flight. The position of the drone has to be presented with a relative high accuracy to obtain accurate

  15. Near-critical-angle scattering for the characterization of clouds of bubbles: particular effects.

    Science.gov (United States)

    Onofri, Fabrice R A; Krzysiek, Mariusz A; Barbosa, Séverine; Messager, Valérie; Ren, Kuan-Fang; Mroczka, Janusz

    2011-10-20

    We report experimental investigations on the influence of various optical effects on the far-field scattering pattern produced by a cloud of optical bubbles near the critical scattering angle. Among the effects considered, there is the change of the relative refractive index of the bubbles (gas bubbles or some liquid-liquid droplets), the influence of intensity gradients induced by the laser beam intensity profile and by the spatial filtering of the collection optics, the coherent and multiple scattering effects occurring for densely packed bubbles, and the tilt angle of spheroidal optical bubbles. The results obtained herein are thought to be fundamental for the development of future works to model these effects and for the extension of the range of applicability of an inverse technique (referenced herein as the critical angle refractometry and sizing technique), which is used to determine the size distribution and composition of bubbly flows.

  16. Compensation of motion error in a high accuracy AFM

    Science.gov (United States)

    Cui, Yuguo; Arai, Yoshikazu; He, Gaofa; Asai, Takemi; Gao, Wei

    2008-10-01

    An atomic force microscope (AFM) system is used for large-area measurement with a spiral scanning strategy, which is composed of an air slide, an air spindle and a probe unit. The motion error which is brought from the air slide and the air spindle will increase with the increasing of the measurement area. Then the measurement accuracy will decrease. In order to achieve a high speed and high accuracy measurement, the probe scans along X-direction with constant height mode driven by the air slide, and at the same time, based on the change way of the motion error, it moves along Zdirection conducted by piezoactuator. According to the above method of error compensation, the profile measurement experiment of a micro-structured surface has been carried out. The experimental result shows that this method is effective for eliminating motion error, and it can achieve high speed and precision measurement of micro-structured surface.

  17. The use of low density high accuracy (LDHA) data for correction of high density low accuracy (HDLA) point cloud

    Science.gov (United States)

    Rak, Michal Bartosz; Wozniak, Adam; Mayer, J. R. R.

    2016-06-01

    Coordinate measuring techniques rely on computer processing of coordinate values of points gathered from physical surfaces using contact or non-contact methods. Contact measurements are characterized by low density and high accuracy. On the other hand optical methods gather high density data of the whole object in a short time but with accuracy at least one order of magnitude lower than for contact measurements. Thus the drawback of contact methods is low density of data, while for non-contact methods it is low accuracy. In this paper a method for fusion of data from two measurements of fundamentally different nature: high density low accuracy (HDLA) and low density high accuracy (LDHA) is presented to overcome the limitations of both measuring methods. In the proposed method the concept of virtual markers is used to find a representation of pairs of corresponding characteristic points in both sets of data. In each pair the coordinates of the point from contact measurements is treated as a reference for the corresponding point from non-contact measurement. Transformation enabling displacement of characteristic points from optical measurement to their match from contact measurements is determined and applied to the whole point cloud. The efficiency of the proposed algorithm was evaluated by comparison with data from a coordinate measuring machine (CMM). Three surfaces were used for this evaluation: plane, turbine blade and engine cover. For the planar surface the achieved improvement was of around 200 μm. Similar results were obtained for the turbine blade but for the engine cover the improvement was smaller. For both freeform surfaces the improvement was higher for raw data than for data after creation of mesh of triangles.

  18. Accuracy Enhancement of Inertial Sensors Utilizing High Resolution Spectral Analysis

    Directory of Open Access Journals (Sweden)

    Michael Korenberg

    2012-08-01

    Full Text Available In both military and civilian applications, the inertial navigation system (INS and the global positioning system (GPS are two complementary technologies that can be integrated to provide reliable positioning and navigation information for land vehicles. The accuracy enhancement of INS sensors and the integration of INS with GPS are the subjects of widespread research. Wavelet de-noising of INS sensors has had limited success in removing the long-term (low-frequency inertial sensor errors. The primary objective of this research is to develop a novel inertial sensor accuracy enhancement technique that can remove both short-term and long-term error components from inertial sensor measurements prior to INS mechanization and INS/GPS integration. A high resolution spectral analysis technique called the fast orthogonal search (FOS algorithm is used to accurately model the low frequency range of the spectrum, which includes the vehicle motion dynamics and inertial sensor errors. FOS models the spectral components with the most energy first and uses an adaptive threshold to stop adding frequency terms when fitting a term does not reduce the mean squared error more than fitting white noise. The proposed method was developed, tested and validated through road test experiments involving both low-end tactical grade and low cost MEMS-based inertial systems. The results demonstrate that in most cases the position accuracy during GPS outages using FOS de-noised data is superior to the position accuracy using wavelet de-noising.

  19. Why is a high accuracy needed in dosimetry. [Radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Lanzl, L.H.

    1976-01-01

    Dose and exposure intercomparisons on a national or international basis have become an important component of quality assurance in the practice of good radiotherapy. A high degree of accuracy of ..gamma.. and x radiation dosimetry is essential in our international society, where medical information is so readily exchanged and used. The value of accurate dosimetry lies mainly in the avoidance of complications in normal tissue and an optimal degree of tumor control.

  20. Navigation message designing with high accuracy for NAV

    Institute of Scientific and Technical Information of China (English)

    Wang Luxiao; Huang Zhigang; Zhao Yun

    2014-01-01

    Navigation message designing with high accuracy guarantee is the key to efficient navi-gation message distribution in the global navigation satellite system (GNSS). Developing high accu-racy-aware navigation message designing algorithms is an important topic. This paper investigates the high-accuracy navigation message designing problem with the message structure unchanged. The contributions made in this paper include a heuristic that employs the concept of the estimated range deviation (ERD) to improve the existing well-known navigation message on L1 frequency (NAV) of global positioning system (GPS) for good accuracy service; a numerical analysis approximation method (NAAM) to evaluate the range error due to truncation (RET) of different navigation messages; and a basic positioning parameters designing algorithm in the limited space allocation. Based on the predicted ultra-rapid data from the ultra-rapid data from the international GPS service for geodynamic (IGU), ERDs are generated in real time for error correction. Simulations show that the algorithms developed in this paper are general and flexible, and thus are applicable to NAV improvement and other navigation message designs.

  1. High Accuracy, Miniature Pressure Sensor for Very High Temperatures Project

    Data.gov (United States)

    National Aeronautics and Space Administration — SiWave proposes to develop a compact, low-cost MEMS-based pressure sensor for very high temperatures and low pressures in hypersonic wind tunnels. Most currently...

  2. High Accuracy Monocular SFM and Scale Correction for Autonomous Driving.

    Science.gov (United States)

    Song, Shiyu; Chandraker, Manmohan; Guest, Clark C

    2016-04-01

    We present a real-time monocular visual odometry system that achieves high accuracy in real-world autonomous driving applications. First, we demonstrate robust monocular SFM that exploits multithreading to handle driving scenes with large motions and rapidly changing imagery. To correct for scale drift, we use known height of the camera from the ground plane. Our second contribution is a novel data-driven mechanism for cue combination that allows highly accurate ground plane estimation by adapting observation covariances of multiple cues, such as sparse feature matching and dense inter-frame stereo, based on their relative confidences inferred from visual data on a per-frame basis. Finally, we demonstrate extensive benchmark performance and comparisons on the challenging KITTI dataset, achieving accuracy comparable to stereo and exceeding prior monocular systems. Our SFM system is optimized to output pose within 50 ms in the worst case, while average case operation is over 30 fps. Our framework also significantly boosts the accuracy of applications like object localization that rely on the ground plane.

  3. Superwide-angle acoustic propagations above the critical angles of the Snell law in liquid—solid superlattice

    Science.gov (United States)

    Zhang, Sai; Zhang, Yu; Gao, Xiao-Wei

    2014-12-01

    In this paper, superwide-angle acoustic propagations above the critical angles of the Snell law in liquid—solid superlattice are investigated. Incident waves above the critical angles of the Snell law usually inevitably induce total reflection. However, incident waves with big oblique angles through the liquid—solid superlattice will produce a superwide angle transmission in a certain frequency range so that total reflection does not occur. Together with the simulation by finite element analysis, theoretical analysis by using transfer matrix method suggests the Bragg scattering of the Lamb waves as the physical mechanism of acoustic wave super-propagation far beyond the critical angle. Incident angle, filling fraction, and material thickness have significant influences on propagation. Superwide-angle propagation phenomenon may have potential applications in nondestructive evaluation of layered structures and controlling of energy flux.

  4. High accuracy and visibility-consistent dense multiview stereo.

    Science.gov (United States)

    Vu, Hoang-Hiep; Labatut, Patrick; Pons, Jean-Philippe; Keriven, Renaud

    2012-05-01

    Since the initial comparison of Seitz et al., the accuracy of dense multiview stereovision methods has been increasing steadily. A number of limitations, however, make most of these methods not suitable to outdoor scenes taken under uncontrolled imaging conditions. The present work consists of a complete dense multiview stereo pipeline which circumvents these limitations, being able to handle large-scale scenes without sacrificing accuracy. Highly detailed reconstructions are produced within very reasonable time thanks to two key stages in our pipeline: a minimum s-t cut optimization over an adaptive domain that robustly and efficiently filters a quasidense point cloud from outliers and reconstructs an initial surface by integrating visibility constraints, followed by a mesh-based variational refinement that captures small details, smartly handling photo-consistency, regularization, and adaptive resolution. The pipeline has been tested over a wide range of scenes: from classic compact objects taken in a laboratory setting, to outdoor architectural scenes, landscapes, and cultural heritage sites. The accuracy of its reconstructions has also been measured on the dense multiview benchmark proposed by Strecha et al., showing the results to compare more than favorably with the current state-of-the-art methods.

  5. Novel method for high accuracy figure measurement of optical flat

    Science.gov (United States)

    E, Kewei; Li, Dahai; Yang, Lijie; Guo, Guangrao; Li, Mengyang; Wang, Xuemin; Zhang, Tao; Xiong, Zhao

    2017-01-01

    Phase Measuring Deflectometry (PMD) is a non-contact, high dynamic-range and full-field metrology which becomes a serious competitor to interferometry. However, the accuracy of deflectometry metrology is strongly influenced by the level of the calibrations, including test geometry, imaging pin-hole camera and digital display. In this paper, we propose a novel method that can measure optical flat surface figure to a high accuracy. We first calibrate the camera using a checker pattern shown on a LCD display at six different orientations, and the last orientation is aligned at the same position as the test optical flat. By using this method, lens distortions and the mapping relationship between the CCD pixels and the subaperture coordinates on the test optical flat can be determined at the same time. To further reduce the influence of the calibration errors on measurements, a reference optical flat with a high quality surface is measured, and then the system errors in our PMD setup can be eliminated by subtracting the figure of the reference flat from the figure of the test flat. Although any expensive coordinates measuring machine, such as laser tracker and coordinates measuring machine are not applied in our measurement, our experimental results of optical flat figure from low to high order aberrations still show a good agreement with that from the Fizeau interferometer.

  6. A semi-numerical model for near-critical angle scattering.

    Science.gov (United States)

    Fradkin, Larissa Ju; Darmon, Michel; Chatillon, Sylvain; Calmon, Pierre

    2016-01-01

    Numerous phenomena in the fields of physics and mathematics as seemingly different as seismology, ultrasonics, crystallography, photonics, relativistic quantum mechanics, and analytical number theory are described by integrals with oscillating integrands that contain three coalescing criticalities, a branch point, stationary phase point, and pole as well as accumulation points at which the speed of integrand oscillation is infinite. Evaluating such integrals is a challenge addressed in this paper. A fast and efficient numerical scheme based on the regularized composite Simpson's rule is proposed, and its efficacy is demonstrated by revisiting the scattering of an elastic plane wave by a stress-free half-plane crack embedded in an isotropic and homogeneous solid. In this canonical problem, the head wave, edge diffracted wave, and reflected (or compensating) wave each can be viewed as a respective contribution of a branch point, stationary phase point, and pole. The proposed scheme allows for a description of the non-classical diffraction effects near the "critical" rays (rays that separate regions irradiated by the head waves from their respective shadow zones). The effects include the spikes present in diffraction coefficients at the critical angles in the far field as well as related interference ripples in the near field.

  7. Bistatic, above-critical angle scattering measurements of fully buried unexploded ordnance (UXO) and clutter.

    Science.gov (United States)

    Waters, Z J; Simpson, H J; Sarkissian, A; Dey, S; Houston, B H; Bucaro, J A; Yoder, T J

    2012-11-01

    Laboratory grade bistatic scattering measurements are conducted in order to examine the acoustic response of realistic fully buried unexploded ordnance (UXO) from above-critical angle insonification, between 2 and 40 kHz. A 127 mm diameter rocket UXO, a 155 mm diameter artillery shell, a natural rock of approximately the same size, and a cinder block are fully buried in water-saturated medium grained sand (mean grain diameter, 240 μm) at depths of 10 cm below the water-sediment interface. A two-dimensional array of bistatic scattering measurements is generated synthetically by scanning a single hydrophone in steps of 3 cm over a 1 m × 1 m patch directly above the targets at a height of 20 cm above the water-sediment interface. Three-dimensional volumetric acoustic images generated from the return waveforms reveal scattering components attributed to geometric and elastic scattering, as well as multiple-scattering interactions of returns between the sediment-water interface and the buried objects. The far-field target strength of the objects is estimated through extrapolation of the angular spectrum. Agreement is found between experimental data and simulated data generated from a finite-element-based, three-dimensional time-harmonic model (2-25 kHz). Separation of the measured UXO from the clutter objects is demonstrated through exploitation of structural-acoustics-based features.

  8. A simple method to measure critical angles for high-sensitivity differential refractometry.

    Science.gov (United States)

    Zilio, S C

    2012-01-16

    A total internal reflection-based differencial refractometer, capable of measuring the real and imaginary parts of the complex refractive index in real time, is presented. The device takes advantage of the phase difference acquired by s- and p-polarized light to generate an easily detectable minimum at the reflected profile. The method allows to sensitively measuring transparent and turbid liquid samples.

  9. High Accuracy Near-infrared Imaging Polarimetry with NICMOS

    CERN Document Server

    Batcheldor, D; Hines, D C; Schmidt, G D; Axon, D J; Robinson, A; Sparks, W; Tadhunter, C

    2008-01-01

    The findings of a nine orbit calibration plan carried out during HST Cycle 15, to fully determine the NICMOS camera 2 (2.0 micron) polarization calibration to high accuracy, are reported. Recently Ueta et al. and Batcheldor et al. have suggested that NICMOS possesses a residual instrumental polarization at a level of 1.2-1.5%. This would completely inhibit the data reduction in a number of GO programs, and hamper the ability of the instrument to perform high accuracy polarimetry. We obtained polarimetric calibration observations of three polarimetric standards at three spacecraft roll angles separated by ~60deg. Combined with archival data, these observations were used to characterize the residual instrumental polarization in order for NICMOS to reach its full potential of accurate imaging polarimetry at p~1%. Using these data, we place an 0.6% upper limit on the instrumental polarization and calculate values of the parallel transmission coefficients that reproduce the ground-based results for the polarimetri...

  10. High-accuracy mass spectrometry for fundamental studies.

    Science.gov (United States)

    Kluge, H-Jürgen

    2010-01-01

    Mass spectrometry for fundamental studies in metrology and atomic, nuclear and particle physics requires extreme sensitivity and efficiency as well as ultimate resolving power and accuracy. An overview will be given on the global status of high-accuracy mass spectrometry for fundamental physics and metrology. Three quite different examples of modern mass spectrometric experiments in physics are presented: (i) the retardation spectrometer KATRIN at the Forschungszentrum Karlsruhe, employing electrostatic filtering in combination with magnetic-adiabatic collimation-the biggest mass spectrometer for determining the smallest mass, i.e. the mass of the electron anti-neutrino, (ii) the Experimental Cooler-Storage Ring at GSI-a mass spectrometer of medium size, relative to other accelerators, for determining medium-heavy masses and (iii) the Penning trap facility, SHIPTRAP, at GSI-the smallest mass spectrometer for determining the heaviest masses, those of super-heavy elements. Finally, a short view into the future will address the GSI project HITRAP at GSI for fundamental studies with highly-charged ions.

  11. Researches on High Accuracy Prediction Methods of Earth Orientation Parameters

    Science.gov (United States)

    Xu, X. Q.

    2015-09-01

    The Earth rotation reflects the coupling process among the solid Earth, atmosphere, oceans, mantle, and core of the Earth on multiple spatial and temporal scales. The Earth rotation can be described by the Earth's orientation parameters, which are abbreviated as EOP (mainly including two polar motion components PM_X and PM_Y, and variation in the length of day ΔLOD). The EOP is crucial in the transformation between the terrestrial and celestial reference systems, and has important applications in many areas such as the deep space exploration, satellite precise orbit determination, and astrogeodynamics. However, the EOP products obtained by the space geodetic technologies generally delay by several days to two weeks. The growing demands for modern space navigation make high-accuracy EOP prediction be a worthy topic. This thesis is composed of the following three aspects, for the purpose of improving the EOP forecast accuracy. (1) We analyze the relation between the length of the basic data series and the EOP forecast accuracy, and compare the EOP prediction accuracy for the linear autoregressive (AR) model and the nonlinear artificial neural network (ANN) method by performing the least squares (LS) extrapolations. The results show that the high precision forecast of EOP can be realized by appropriate selection of the basic data series length according to the required time span of EOP prediction: for short-term prediction, the basic data series should be shorter, while for the long-term prediction, the series should be longer. The analysis also showed that the LS+AR model is more suitable for the short-term forecasts, while the LS+ANN model shows the advantages in the medium- and long-term forecasts. (2) We develop for the first time a new method which combines the autoregressive model and Kalman filter (AR+Kalman) in short-term EOP prediction. The equations of observation and state are established using the EOP series and the autoregressive coefficients

  12. Researching the technology of high-accuracy camshaft measurement

    Science.gov (United States)

    Chen, Wei; Chen, Yong-Le; Wang, Hong; Liao, Hai-Yang

    1996-10-01

    This paper states the cam's data processing algorithm in detail in high accurate camshaft measurement system. It contains: 1) using minimum error of curve symmetry to seek the center position of the key slot; 2) Calculating the minimum error by cam's curve in theory to search top area; 3) According to cam's tolerance E(i) function and minimum angle error at cam top, seeking the best position of cam top and getting the best angle value and error curve. The algorithm is suitable for measuring all kinds of symmetry or asymmetry cam, and plain push-rod or spherical push-rod cam, for example, bus camshaft, car camshaft, motor camshaft, etc. Using the algorithm, high accuracy measurement can be achieved.

  13. Read-only high accuracy volume holographic optical correlator

    Science.gov (United States)

    Zhao, Tian; Li, Jingming; Cao, Liangcai; He, Qingsheng; Jin, Guofan

    2011-10-01

    A read-only volume holographic correlator (VHC) is proposed. After the recording of all of the correlation database pages by angular multiplexing, a stand-alone read-only high accuracy VHC will be separated from the VHC recording facilities which include the high-power laser and the angular multiplexing system. The stand-alone VHC has its own low power readout laser and very compact and simple structure. Since there are two lasers that are employed for recording and readout, respectively, the optical alignment tolerance of the laser illumination on the SLM is very sensitive. The twodimensional angular tolerance is analyzed based on the theoretical model of the volume holographic correlator. The experimental demonstration of the proposed read-only VHC is introduced and discussed.

  14. Spatial augmented reality based high accuracy human face projection

    Science.gov (United States)

    Li, Dong; Xie, Jinghui; Li, Yufeng; Weng, Dongdong; Liu, Yue

    2015-08-01

    This paper discusses the imaging principles and the technical difficulties of spatial augmented reality based human face projection. A novel geometry correction method is proposed to realize fast, high-accuracy face model projection. Using a depth camera to reconstruct the projected object, the relative position from the rendered model to the projector can be accessed and the initial projection image is generated. Then the projected image is distorted by using Bezier interpolation to guarantee that the projected texture matches with the object surface. The proposed method is under a simple process flow and can achieve high perception registration of virtual and real object. In addition, this method has a good performance in the condition that the reconstructed model is not exactly same with the rendered virtual model which extends its application area in the spatial augmented reality based human face projection.

  15. Ray-tracing critical-angle transmission gratings for the X-ray Surveyor and Explorer-size missions

    Science.gov (United States)

    Günther, Hans M.; Bautz, Marshall W.; Heilmann, Ralf K.; Huenemoerder, David P.; Marshall, Herman L.; Nowak, Michael A.; Schulz, Norbert S.

    2016-07-01

    We study a critical angle transmission (CAT) grating spectrograph that delivers a spectral resolution significantly above any X-ray spectrograph ever own. This new technology will allow us to resolve kinematic components in absorption and emission lines of galactic and extragalactic matter down to unprecedented dispersion levels. We perform ray-trace simulations to characterize the performance of the spectrograph in the context of an X-ray Surveyor or Arcus like layout (two mission concepts currently under study). Our newly developed ray-trace code is a tool suite to simulate the performance of X-ray observatories. The simulator code is written in Python, because the use of a high-level scripting language allows modifications of the simulated instrument design in very few lines of code. This is especially important in the early phase of mission development, when the performances of different configurations are contrasted. To reduce the run-time and allow for simulations of a few million photons in a few minutes on a desktop computer, the simulator code uses tabulated input (from theoretical models or laboratory measurements of samples) for grating efficiencies and mirror reflectivities. We find that the grating facet alignment tolerances to maintain at least 90% of resolving power that the spectrometer has with perfect alignment are (i) translation parallel to the optical axis below 0.5 mm, (ii) rotation around the optical axis or the groove direction below a few arcminutes, and (iii) constancy of the grating period to 1:105. Translations along and rotations around the remaining axes can be significantly larger than this without impacting the performance.

  16. High accuracy mantle convection simulation through modern numerical methods

    KAUST Repository

    Kronbichler, Martin

    2012-08-21

    Numerical simulation of the processes in the Earth\\'s mantle is a key piece in understanding its dynamics, composition, history and interaction with the lithosphere and the Earth\\'s core. However, doing so presents many practical difficulties related to the numerical methods that can accurately represent these processes at relevant scales. This paper presents an overview of the state of the art in algorithms for high-Rayleigh number flows such as those in the Earth\\'s mantle, and discusses their implementation in the Open Source code Aspect (Advanced Solver for Problems in Earth\\'s ConvecTion). Specifically, we show how an interconnected set of methods for adaptive mesh refinement (AMR), higher order spatial and temporal discretizations, advection stabilization and efficient linear solvers can provide high accuracy at a numerical cost unachievable with traditional methods, and how these methods can be designed in a way so that they scale to large numbers of processors on compute clusters. Aspect relies on the numerical software packages deal.II and Trilinos, enabling us to focus on high level code and keeping our implementation compact. We present results from validation tests using widely used benchmarks for our code, as well as scaling results from parallel runs. © 2012 The Authors Geophysical Journal International © 2012 RAS.

  17. Critical-angle x-ray transmission grating spectrometer with extended bandpass and resolving power > 10,000

    Science.gov (United States)

    Heilmann, Ralf K.; Bruccoleri, Alexander R.; Kolodziejczak, Jeffery; Gaskin, Jessica A.; O'Dell, Stephen L.; Bhatia, Ritwik; Schattenburg, Mark L.

    2016-07-01

    A number of high priority subjects in astrophysics can be addressed by a state-of-the-art soft x-ray grating spectrometer, such as the role of Active Galactic Nuclei in galaxy and star formation, characterization of the Warm-Hot Intergalactic Medium and the missing baryon problem, characterization of halos around the Milky Way and nearby galaxies, as well as stellar coronae and surrounding winds and disks. An Explorer-scale, largearea (> 1,000 cm2), high resolving power (R =λ/Δλ > 3,000) soft x-ray grating spectrometer is highly feasible based on Critical-Angle Transmission (CAT) grating technology, even for telescopes with angular resolution of 5-10 arcsec. Still, significantly higher performance can be provided by a CAT grating spectrometer on an X-ray- Surveyor-type mission. CAT gratings combine the advantages of blazed reflection gratings (high efficiency, use of higher diffraction orders) with those of conventional transmission gratings (lowmass, relaxed alignment tolerances and temperature requirements, transparent at higher energies) with minimalmission resource requirements. They are high-efficiency blazed transmission gratings that consist of freestanding, ultra-high aspect-ratio grating bars fabricated from silicon-on-insulator (SOI) wafers using advanced anisotropic dry and wet etch techniques. Blazing is achieved through grazing-incidence reflection off the smooth grating bar sidewalls. The reflection properties of silicon are well matched to the soft x-ray band, and existing silicon CAT gratings can exceed 30% absolute diffraction efficiency, with clear paths for further improvement. Nevertheless, CAT gratings with sidewalls made of higher atomic number elements allow extension of the CAT grating principle to higher energies and larger dispersion angles, thus enabling higher resolving power at shorter wavelengths. We show x-ray data from CAT gratings coated with a thin layer of platinum using atomic layer deposition, and demonstrate efficient

  18. Monitoring techniques for high accuracy interference fit assembly processes

    Science.gov (United States)

    Liuti, A.; Vedugo, F. Rodriguez; Paone, N.; Ungaro, C.

    2016-06-01

    In the automotive industry, there are many assembly processes that require a high geometric accuracy, in the micrometer range; generally open-loop controllers cannot meet these requirements. This results in an increased defect rate and high production costs. This paper presents an experimental study of interference fit process, aimed to evaluate the aspects which have the most impact on the uncertainty in the final positioning. The press-fitting process considered, consists in a press machine operating with a piezoelectric actuator to press a plug into a sleeve. Plug and sleeve are designed and machined to obtain a known interference fit. Differential displacement and velocity measurements of the plug with respect to the sleeve are measured by a fiber optic differential laser Doppler vibrometer. Different driving signals of the piezo actuator allow to have an insight into the differences between a linear and a pulsating press action. The paper highlights how the press-fit assembly process is characterized by two main phases: the first is an elastic deformation of the plug and sleeve, which produces a reversible displacement, the second is a sliding of the plug with respect to the sleeve, which results in an irreversible displacement and finally realizes the assembly. The simultaneous measurements of the displacement and the force have permitted to define characteristic features in the signal useful to identify the start of the irreversible movement. These indicators could be used to develop a control logic in a press assembly process.

  19. A high-accuracy DCO with hybrid architecture

    Science.gov (United States)

    Sun, Yapeng; Zhao, Huidong; Qiao, Shushan; Hei, Yong; Zhang, Fuhai

    2017-07-01

    In this paper, a novel hybrid digital-controlled oscillator (DCO) is proposed, which is used to improve the accuracy of the all-digital clock generator without reference source. The DCO with hybrid architecture consists of two parts: DCO_high and DCO_low. The DCO_high decides the coarse output frequency of DCO, and adopts the cascade structure to decrease the area. The DCO_low adopts the chain structure with three-state buffer, and decides the fine output frequency of DCO. Compared with traditional cascade DCO, the proposed hybrid DCO features higher precision with less inherent delay. Therefore the clock generator can tolerate process, voltage and temperature (PVT) variation and meet the needs of different conditions. The DCO is designed in SMIC 180 nm CMOS process with 0.021 mm2 chip area. The output frequency is adjusted from 15-120 MHz. The frequency error is less than 0.83% at 25 MHz with 1.6-1.8 V supply voltage and 0-80 °C temperature variations in TT, FF, SS corners. Project supported by the National Natural Science Foundation of China (Nos. 61306025, 61474135).

  20. Hydraulic support stability control of fully mechanized top coal caving face with steep coal seams based on instable critical angle

    Institute of Scientific and Technical Information of China (English)

    TO Shi-hao; YUAN Yong; LI Nai-liang; DOU Feng-jin; WANG Fang-tian

    2008-01-01

    Analyzed the support instable mode of sliding, tripping, and so on, and believedthe key point of the support stability control of fully mechanized coal caving face with steepcoal seams was to maintain that the seam true angle was less than the hydraulic supportinstability critical angle. Through the layout of oblique face, the improvement of supportsetting load, the control of mining height and nonskid platform, the group support systemof end face, the advance optimization of conveyor and support, and the other control tech-nical measures, the true angle of the seam is reduced and the instable critical angle of thesupport is increased, the hydraulic support stability of fully mechanized coal caving facewith steep coal seams is effectively controlled.

  1. Determination of UAV position using high accuracy navigation platform

    Directory of Open Access Journals (Sweden)

    Ireneusz Kubicki

    2016-07-01

    Full Text Available The choice of navigation system for mini UAV is very important because of its application and exploitation, particularly when the installed on it a synthetic aperture radar requires highly precise information about an object’s position. The presented exemplary solution of such a system draws attention to the possible problems associated with the use of appropriate technology, sensors, and devices or with a complete navigation system. The position and spatial orientation errors of the measurement platform influence on the obtained SAR imaging. Both, turbulences and maneuvers performed during flight cause the changes in the position of the airborne object resulting in deterioration or lack of images from SAR. Consequently, it is necessary to perform operations for reducing or eliminating the impact of the sensors’ errors on the UAV position accuracy. You need to look for compromise solutions between newer better technologies and in the field of software. Keywords: navigation systems, unmanned aerial vehicles, sensors integration

  2. Key technologies for high-accuracy large mesh antenna reflectors

    Science.gov (United States)

    Meguro, Akira; Harada, Satoshi; Watanabe, Mitsunobu

    2003-12-01

    Nippon Telephone and Telegram Corporation (NTT) continues to develop the modular mesh-type deployable antenna. Antenna diameter can be changed from 5 m to about 20 m by changing the number of modules used with surface accuracy better than 2.4 mm RMS (including all error factors) with sufficient deployment reliability. Key technologies are the antenna's structural design, the deployment mechanism, the design tool, the analysis tool, and modularized testing/evaluation methods. This paper describes our beam steering mechanism. Tests show that it yields a beam pointing accuracy of better than 0.1°. Based on the S-band modular mesh antenna reflector, the surface accuracy degradation factors that must be considered in designing the new antenna are partially identified. The influence of modular connection errors on surface accuracy is quantitatively estimated. Our analysis tool SPADE is extended to include the addition of joint gaps. The addition of gaps allows non-linear vibration characteristics due to gapping in deployment hinges to be calculated. We intend to design a new type of mesh antenna reflector. Our new goal is an antenna for Ku or Ka band satellite communication. For this mission, the surface shape must be 5 times more accurate than is required for an S-band antenna.

  3. High Accuracy and Real-Time Gated Viewing Laser Radar

    Institute of Scientific and Technical Information of China (English)

    Dong Li; Hua-Jun Yang; Shan-Pei Zhou

    2011-01-01

    A gated viewing laser radar has an excellent performance in underwater low light level imaging,and it also provides a viable solution to inhibit backscattering.In this paper,a gated viewing imaging system according to the demand for real-time imaging is presented,and then the simulation is used to analyze the performance of the real-time gated viewing system.The range accuracy performance is limited by the slice number,the width of gate,the delay time step,the initial delay time,as well as the system noise and atmospheric turbulence.The simulation results indicate that the highest range accuracy can be achieved when the system works with the optimal parameters.Finally,how to choose the optimal parameters has been researched.

  4. Determination of the refractive index of glucose-ethanol-water mixtures using spectroscopic refractometry near the critical angle.

    Science.gov (United States)

    Sobral, H; Peña-Gomar, M

    2015-10-01

    A spectroscopic refractometer was used to investigate the dispersion curves of ethanol and D-glucose solutions in water near the critical angle; here, the reflectivity was measured using a white source. Dispersion curves were obtained in the 320-1000 nm wavelength range with a resolution better than 10(-4) for the refractive index, n. The differential refractive index is measured as a function of wavelength, and a simple expression is proposed to obtain the refractive index of the glucose-ethanol-water ternary system. Using this expression, combined with the experimental differential refractive index values, the concentrations of individual components can be calculated.

  5. High Accuracy Thermal Expansion Measurement at Cryogenic Temperatures

    Science.gov (United States)

    Tucker, Jim; Despit, Gregory; Stallcup, Michael; Presson, Joan; Nein, Max

    2003-01-01

    A new, interferometer-based system for measuring thermal expansion to an absolute accuracy of 20 ppb or better at cryogenic temperatures has been developed. Data from NIST Copper SRM 736 measured from room temperature to 15 K will be presented along with data from many other materials including beryllium, ULE, Zerodur, and composite materials. Particular attention will be given to a study by the Space Optics Manufacturing Technology Center (SOMTC) investigating the variability of ULE and beryllium materials used in the AMSD program Approximately 20 samples of each material, tested from room temperature to below 30 K are compared as a function of billet location.

  6. Application of the critical angle method to refractive index measurement of human skin in vivo under partial contact.

    Science.gov (United States)

    Yoshida, Kenichiro; Ohkubo, Kohji; Ojima, Nobutoshi; Iwata, Kayoko

    2013-03-01

    We adapted the critical angle method for measuring rough surfaces under partial contact to acquire an in vivo skin refractive index (RI). Assuming that the total reflection is the simple sum of reflection from areas that are in contact and reflection from those that are not in contact, the RI can be estimated even for partial contact with a rough surface. We found that cheek skin is sufficiently soft that a sufficiently large area can be in contact and that the critical angle was detectable. The RIs of the cheeks of adult females were measured. The RI range was about 1.51 to 1.53, at a wavelength of 550 nm, without considering systematic errors. The RIs of cheeks are significantly correlated with their conductance, which corresponds to their water content. We determined the relationship between the RI and conductance within the variation of skin under normal conditions; this relationship was theoretically obtained in previous studies. In the present study, a direct in vivo measurement method was developed that enabled us to measure the RI in daily life, although this method contains errors for several reasons, including disregarding absorption.

  7. Design of a high linearity and high gain accuracy analog baseband circuit for DAB receiver

    Science.gov (United States)

    Li, Ma; Zhigong, Wang; Jian, Xu; Yiqiang, Wu; Junliang, Wang; Mi, Tian; Jianping, Chen

    2015-02-01

    An analog baseband circuit of high linearity and high gain accuracy for a digital audio broadcasting receiver is implemented in a 0.18-μm RFCMOS process. The circuit comprises a 3rd-order active-RC complex filter (CF) and a programmable gain amplifier (PGA). An automatic tuning circuit is also designed to tune the CF's pass band. Instead of the class-A fully differential operational amplifier (FDOPA) adopted in the conventional CF and PGA design, a class-AB FDOPA is specially employed in this circuit to achieve a higher linearity and gain accuracy for its large current swing capability with lower static current consumption. In the PGA circuit, a novel DC offset cancellation technique based on the MOS resistor is introduced to reduce the settling time significantly. A reformative switching network is proposed, which can eliminate the switch resistor's influence on the gain accuracy of the PGA. The measurement result shows the gain range of the circuit is 10-50 dB with a 1-dB step size, and the gain accuracy is less than ±0.3 dB. The OIP3 is 23.3 dBm at the gain of 10 dB. Simulation results show that the settling time is reduced from 100 to 1 ms. The image band rejection is about 40 dB. It only draws 4.5 mA current from a 1.8 V supply voltage.

  8. Frequency Comparison of Two High-Accuracy Al+ Optical Clocks

    CERN Document Server

    Chou, C -W; Koelemeij, J C J; Wineland, D J; Rosenband, T

    2009-01-01

    We have constructed an optical clock with a fractional frequency inaccuracy of 8.6e-18, based on quantum logic spectroscopy of an Al+ ion. A simultaneously trapped Mg+ ion serves to sympathetically laser-cool the Al+ ion and detect its quantum state. The frequency of the 1S0->3P0 clock transition is compared to that of a previously constructed Al+ optical clock with a statistical measurement uncertainty of 7.0e-18. The two clocks exhibit a relative stability of 2.8e-15/ sqrt(tau), and a fractional frequency difference of -1.8e-17, consistent with the accuracy limit of the older clock.

  9. Frequency Comparison of Two High-Accuracy Al+ Optical Clocks

    Science.gov (United States)

    Chou, C. W.; Hume, D. B.; Koelemeij, J. C. J.; Wineland, D. J.; Rosenband, T.

    2010-02-01

    We have constructed an optical clock with a fractional frequency inaccuracy of 8.6×10-18, based on quantum logic spectroscopy of an Al+ ion. A simultaneously trapped Mg+ ion serves to sympathetically laser cool the Al+ ion and detect its quantum state. The frequency of the S01↔P03 clock transition is compared to that of a previously constructed Al+ optical clock with a statistical measurement uncertainty of 7.0×10-18. The two clocks exhibit a relative stability of 2.8×10-15τ-1/2, and a fractional frequency difference of -1.8×10-17, consistent with the accuracy limit of the older clock.

  10. Sensitivity analysis for high accuracy proximity effect correction

    Science.gov (United States)

    Thrun, Xaver; Browning, Clyde; Choi, Kang-Hoon; Figueiro, Thiago; Hohle, Christoph; Saib, Mohamed; Schiavone, Patrick; Bartha, Johann W.

    2015-10-01

    A sensitivity analysis (SA) algorithm was developed and tested to comprehend the influences of different test pattern sets on the calibration of a point spread function (PSF) model with complementary approaches. Variance-based SA is the method of choice. It allows attributing the variance of the output of a model to the sum of variance of each input of the model and their correlated factors.1 The objective of this development is increasing the accuracy of the resolved PSF model in the complementary technique through the optimization of test pattern sets. Inscale® from Aselta Nanographics is used to prepare the various pattern sets and to check the consequences of development. Fraunhofer IPMS-CNT exposed the prepared data and observed those to visualize the link of sensitivities between the PSF parameters and the test pattern. First, the SA can assess the influence of test pattern sets for the determination of PSF parameters, such as which PSF parameter is affected on the employments of certain pattern. Secondly, throughout the evaluation, the SA enhances the precision of PSF through the optimization of test patterns. Finally, the developed algorithm is able to appraise what ranges of proximity effect correction is crucial on which portion of a real application pattern in the electron beam exposure.

  11. Maximal breaking of symmetry at critical angles and a closed-form expression for angular deviations of the Snell law

    Science.gov (United States)

    Araújo, Manoel P.; Carvalho, Silvânia A.; De Leo, Stefano

    2014-09-01

    A detailed analysis of the propagation of laser Gaussian beams at critical angles shows under which conditions it is possible to maximize the breaking of symmetry in the angular distribution and for which values of the laser wavelength and beam waist it is possible to find an analytic formula for the maximal angular deviation from the optical path predicted by the Snell law. For beam propagation through N dielectric blocks and for a maximal breaking of symmetry, a closed expression for the Goos-Hänchen shift is obtained. The multiple-peak phenomenon clearly represents additional evidence of the breaking of symmetry in the angular distribution of optical beams. Finally, the laser wavelength and beam-waist conditions to produce focal effects in the outgoing beam are also briefly discussed.

  12. Distributed High Accuracy Peer-to-Peer Localization in Mobile Multipath Environments

    CERN Document Server

    Ekambaram, Venkatesan

    2010-01-01

    In this paper we consider the problem of high accuracy localization of mobile nodes in a multipath-rich environment where sub-meter accuracies are required. We employ a peer to peer framework where the vehicles/nodes can get pairwise multipath-degraded ranging estimates in local neighborhoods together with a fixed number of anchor nodes. The challenge is to overcome the multipath-barrier with redundancy in order to provide the desired accuracies especially under severe multipath conditions when the fraction of received signals corrupted by multipath is dominating. We invoke a message passing analytical framework based on particle filtering and reveal its high accuracy localization promise through simulations.

  13. High-accuracy Subdaily ERPs from the IGS

    Science.gov (United States)

    Ray, J. R.; Griffiths, J.

    2012-04-01

    Since November 2000 the International GNSS Service (IGS) has published Ultra-rapid (IGU) products for near real-time (RT) and true real-time applications. They include satellite orbits and clocks, as well as Earth rotation parameters (ERPs) for a sliding 48-hr period. The first day of each update is based on the most recent GPS and GLONASS observational data from the IGS hourly tracking network. At the time of release, these observed products have an initial latency of 3 hr. The second day of each update consists of predictions. So the predictions between about 3 and 9 hr into the second half are relevant for true RT uses. Originally updated twice daily, the IGU products since April 2004 have been issued every 6 hr, at 3, 9, 15, and 21 UTC. Up to seven Analysis Centers (ACs) contribute to the IGU combinations. Two sets of ERPs are published with each IGU update, observed values at the middle epoch of the first half and predicted values at the middle epoch of the second half. The latency of the near RT ERPs is 15 hr while the predicted ERPs, based on projections of each AC's most recent determinations, are issued 9 hr ahead of their reference epoch. While IGU ERPs are issued every 6 hr, each set represents an integrated estimate over the surrounding 24 hr. So successive values are temporally correlated with about 75% of the data being common; this fact should be taken into account in user assimilations. To evaluate the accuracy of these near RT and predicted ERPs, they have been compared to the IGS Final ERPs, available about 11 to 17 d after data collection. The IGU products improved dramatically in the earlier years but since about 2008.0 the performance has been stable and excellent. During the last three years, RMS differences for the observed IGU ERPs have been about 0.036 mas and 0.0101 ms for each polar motion component and LOD respectively. (The internal precision of the reference IGS ERPs over the same period is about 0.016 mas for polar motion and 0

  14. A study for high accuracy real-time 3D ultrasonic location system.

    Science.gov (United States)

    Zhou, Ping; Ha, Zhang; Zhou, Kangyuan

    2006-12-22

    We discussed a high accuracy real-time 3D ultrasonic location system in this article. The signal received was sampled after it passed the TGC and the logarithmic amplifier. Inside the DSP, we used the dynamic threshold tracing technique to improve the accuracy. The result was processed with Weighted Arithmetic Average. By testing the 40 kHz 3D location system, we have arrived at the accuracy of 1 cm.

  15. Accuracy of Handheld Blood Glucose Meters at High Altitude

    NARCIS (Netherlands)

    de Mol, Pieter; Krabbe, Hans G.; de Vries, Suzanna T.; Fokkert, Marion J.; Dikkeschei, Bert D.; Rienks, Rienk; Bilo, Karin M.; Bilo, Henk J. G.

    2010-01-01

    Background: Due to increasing numbers of people with diabetes taking part in extreme sports (e. g., high-altitude trekking), reliable handheld blood glucose meters (BGMs) are necessary. Accurate blood glucose measurement under extreme conditions is paramount for safe recreation at altitude. Prior st

  16. Development of high accuracy and resolution geoid and gravity maps

    Science.gov (United States)

    Gaposchkin, E. M.

    1986-01-01

    Precision satellite to satellite tracking can be used to obtain high precision and resolution maps of the geoid. A method is demonstrated to use data in a limited region to map the geopotential at the satellite altitude. An inverse method is used to downward continue the potential to the Earth surface. The method is designed for both satellites in the same low orbit.

  17. High accuracy magnetic field sensors with wide operation temperature range

    Science.gov (United States)

    Vasil'evskii, I. S.; Vinichenko, A. N.; Rubakin, D. I.; Bolshakova, I. A.; Kargin, N. I.

    2016-10-01

    n+InAs(Si) epitaxial thin films heavily doped by silicon and Hall effect magnetic field sensors based on this structures have been fabricated and studied. We have demonstrated the successful formation of highly doped InAs thin films (∼100 nm) with the different intermediate layer arrangement and appropriate electron mobility values. Hall sensors performance parameters have been measured in wide temperature range. Obtained sensitivity varied from 1 to 40 Ω/T, while the best linearity and lower temperature coefficient have been found in the higher doped samples with lower electron mobility. We attribute this to the electron system degeneracy and decreased phonon contribution to electron mobility and resistance.

  18. A High Accuracy Method for Semi-supervised Information Extraction

    Energy Technology Data Exchange (ETDEWEB)

    Tratz, Stephen C.; Sanfilippo, Antonio P.

    2007-04-22

    Customization to specific domains of dis-course and/or user requirements is one of the greatest challenges for today’s Information Extraction (IE) systems. While demonstrably effective, both rule-based and supervised machine learning approaches to IE customization pose too high a burden on the user. Semi-supervised learning approaches may in principle offer a more resource effective solution but are still insufficiently accurate to grant realistic application. We demonstrate that this limitation can be overcome by integrating fully-supervised learning techniques within a semi-supervised IE approach, without increasing resource requirements.

  19. Traffic Sign Recognition with High Accuracy Using Mixture of Experts

    Directory of Open Access Journals (Sweden)

    Reza Azad

    2014-06-01

    Full Text Available Traffic signs provide the driver various information for safe and efficient navigation. Automatic recognition of traffic signs is, therefore, important for automated driving or driver assistance systems.In this paper, a new and efficient traffic sign recognition system based on extracting diverse feature set, and applying mixture of experts'architecture on the extracted featuresis proposed.In the result part, the proposed approach is evaluated on the German traffic sign recognition and Grigorescu traffic signsbenchmark and high recognition rate is achieved.Comparison with some of the most related methods indicates that the proposed novel model yields excellent recognition rate in traffic sign recognition that is the recognition rate of 99.94% for the training set and 98.50% for the test set.In addition, experimental results have demonstrated our method robust in successful recognition of traffic signs even with variant lighting.

  20. Gated viewing and high-accuracy three-dimensional laser radar

    DEFF Research Database (Denmark)

    Busck, Jens; Heiselberg, Henning

    2004-01-01

    We have developed a fast and high-accuracy three-dimensional (3-D) imaging laser radar that can achieve better than 1 mm range accuracy for half a million pixels in less than 1 s. Our technique is based on range-gating segmentation. We combine the advantages of gated viewing with our new fast...

  1. Gated viewing and high-accuracy three-dimensional laser radar

    DEFF Research Database (Denmark)

    Busck, Jens; Heiselberg, Henning

    2004-01-01

    We have developed a fast and high-accuracy three-dimensional (3-D) imaging laser radar that can achieve better than 1 mm range accuracy for half a million pixels in less than 1 s. Our technique is based on range-gating segmentation. We combine the advantages of gated viewing with our new fast...

  2. A High-Throughput, High-Accuracy System-Level Simulation Framework for System on Chips

    Directory of Open Access Journals (Sweden)

    Guanyi Sun

    2011-01-01

    Full Text Available Today's System-on-Chips (SoCs design is extremely challenging because it involves complicated design tradeoffs and heterogeneous design expertise. To explore the large solution space, system architects have to rely on system-level simulators to identify an optimized SoC architecture. In this paper, we propose a system-level simulation framework, System Performance Simulation Implementation Mechanism, or SPSIM. Based on SystemC TLM2.0, the framework consists of an executable SoC model, a simulation tool chain, and a modeling methodology. Compared with the large body of existing research in this area, this work is aimed at delivering a high simulation throughput and, at the same time, guaranteeing a high accuracy on real industrial applications. Integrating the leading TLM techniques, our simulator can attain a simulation speed that is not slower than that of the hardware execution by a factor of 35 on a set of real-world applications. SPSIM incorporates effective timing models, which can achieve a high accuracy after hardware-based calibration. Experimental results on a set of mobile applications proved that the difference between the simulated and measured results of timing performance is within 10%, which in the past can only be attained by cycle-accurate models.

  3. The accuracy of QCD perturbation theory at high energies

    CERN Document Server

    Dalla Brida, Mattia; Korzec, Tomasz; Ramos, Alberto; Sint, Stefan; Sommer, Rainer

    2016-01-01

    We discuss the determination of the strong coupling $\\alpha_\\mathrm{\\overline{MS}}^{}(m_\\mathrm{Z})$ or equivalently the QCD $\\Lambda$-parameter. Its determination requires the use of perturbation theory in $\\alpha_s(\\mu)$ in some scheme, $s$, and at some energy scale $\\mu$. The higher the scale $\\mu$ the more accurate perturbation theory becomes, owing to asymptotic freedom. As one step in our computation of the $\\Lambda$-parameter in three-flavor QCD, we perform lattice computations in a scheme which allows us to non-perturbatively reach very high energies, corresponding to $\\alpha_s = 0.1$ and below. We find that perturbation theory is very accurate there, yielding a three percent error in the $\\Lambda$-parameter, while data around $\\alpha_s \\approx 0.2$ is clearly insufficient to quote such a precision. It is important to realize that these findings are expected to be generic, as our scheme has advantageous properties regarding the applicability of perturbation theory.

  4. Methodology of High Accuracy and Resolution 3D Geological Model Generation and Application

    Institute of Scientific and Technical Information of China (English)

    吴键; 曹代勇; 邓爱居; 李东津; 蒋涛; 翟光华

    2004-01-01

    By generating a high accuracy and high resolution geological model in Liuchu oil field, the technique of geological modeling is expanded and involved in primary geological study, making the sand bodies and reservoir be easily described in detail. The 3D visualization and 3D interactive editing of geological structure model are the key for modeling procedure. And a high accuracy and resolution geological model has been well applied in optimizing the production scheme.

  5. High-speed, high-accuracy large range 3D measurement

    Science.gov (United States)

    An, Yatong; Zhang, Song

    2017-05-01

    This paper presents such a high-speed, high-accuracy structured light technique that could achieve large range 3D shape measurement. The enabling method is our recently proposed system calibration that splits the calibration process into two stages. Specifically, we calibrate the intrinsic parameters at a near position with a regular size yet precisely fabricated calibration target, and then calibrate the extrinsic parameters with the assistance of an additional large range yet low accuracy low cost 3D scanner (i.e., Kinect). We developed a system that achieved 500 Hz with a resolution 2304 × 1400. The field of view (FOV) of our structured light system is 0.9 m(W) × 1.4 m(H) × 0.8 m(D). Our experimental data demonstrated that such a large range structured light system can achieve an mean error of 0.13 mm with a standard deviation of 1.18 mm by measuring a 304.8 mm diameter sphere. We further experimentally demonstrated that proposed method can simultaneously measure multiple objects or large dynamically changing objects.

  6. State of the art in high accuracy high detail DTMs derived from ALS

    Science.gov (United States)

    Pfeifer, N.; Briese, C.; Mandlburger, G.; Höfle, B.; Ressl, C.

    2009-04-01

    High-resolution Digital Terrain Models (DTMs) representing the bare Earth are a fundamental input for various applications in geomorphology. Airborne laser scanning (ALS) is established as a standard tool for deriving DTMs over large areas with unprecedented accuracy. Due to advances in sensor technology and in processing algorithms in the recent years the obtainable accuracy is still increasing. Accuracy is understood as the deviation from the elevation at one specified point to its true value. These advances may lead to a more efficient data acquisition, if reduced accuracy is targeted, but also allow data acquisition schemes with more detail becoming visible, i.e. small features of the relief. For the latter a high internal precision, i.e. repeatability, is necessary. The essential advances in the technologies are improvements in ranging through the introduction of full-waveform (FWF) laser scanning and rigorous models of strip adjustment. In FWF laser scanning the time-dependent strength of the backscattered signal is recorded. This is opposed to the analogue processing of the incoming energy and storage of one arrival time of discrete-return systems. In a simple one-echo situation, the arrival time corresponds to the maximum of the waveform. By applying a decomposition of the full waveform into single echoes, which are transformed copies of the emitted signal, it is possible to retrieve more echoes per shot. Additionally, if echoes of individual scatterers are overlapping, FWF sensors might be able to separate them, whereas discrete return systems might rather only be able to derive one collective arrival time. Finally, the overlay of two echoes does not have the maxima at the same positions as the individual echoes. Additionally, the pulse repetition rate of laser scanners has increased, which allows higher point densities and therefore higher richness of detail. These advances in data acquisition increase the precision within one ALS strip. Deficiencies in

  7. High-accuracy determination for optical indicatrix rotation in ferroelectric DTGS

    OpenAIRE

    O.S.Kushnir; O.A.Bevz; O.G.Vlokh

    2000-01-01

    Optical indicatrix rotation in deuterated ferroelectric triglycine sulphate is studied with the high-accuracy null-polarimetric technique. The behaviour of the effect in ferroelectric phase is referred to quadratic spontaneous electrooptics.

  8. High-accuracy interferometric measurements of flatness and parallelism of a step gauge

    CSIR Research Space (South Africa)

    Kruger, OA

    2001-01-01

    Full Text Available for the calibration of step gauges to a high accuracy. A system was also developed for interferometric measurements of the flatness and parallelism of gauge block faces for use in uncertainty calculations....

  9. High Accuracy Reference Network (HARN), Points generated from coordinates supplied by NGS, Published in 1993, MARIS.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This High Accuracy Reference Network (HARN) dataset, was produced all or in part from Field Survey/GPS information as of 1993. It is described as 'Points generated...

  10. Data supporting the high-accuracy haplotype imputation using unphased genotype data as the references

    Directory of Open Access Journals (Sweden)

    Wenzhi Li

    2016-09-01

    Full Text Available The data presented in this article is related to the research article entitled “High-accuracy haplotype imputation using unphased genotype data as the references” which reports the unphased genotype data can be used as reference for haplotyping imputation [1]. This article reports different implementation generation pipeline, the results of performance comparison between different implementations (A, B, and C and between HiFi and three major imputation software tools. Our data showed that the performances of these three implementations are similar on accuracy, in which the accuracy of implementation-B is slightly but consistently higher than A and C. HiFi performed better on haplotype imputation accuracy and three other software performed slightly better on genotype imputation accuracy. These data may provide a strategy for choosing optimal phasing pipeline and software for different studies.

  11. High-Order Kinetic Relaxation Schemes as High-Accuracy Poisson Solvers

    CERN Document Server

    Mendoza, M; Herrmann, H J

    2015-01-01

    We present a new approach to find accurate solutions to the Poisson equation, as obtained from the steady-state limit of a diffusion equation with strong source terms. For this purpose, we start from Boltzmann's kinetic theory and investigate the influence of higher order terms on the resulting macroscopic equations. By performing an appropriate expansion of the equilibrium distribution, we provide a method to remove the unnecessary terms up to a desired order and show that it is possible to find, with high level of accuracy, the steady-state solution of the diffusion equation for sizeable Knudsen numbers. In order to test our kinetic approach, we discretise the Boltzmann equation and solve the Poisson equation, spending up to six order of magnitude less computational time for a given precision than standard lattice Boltzmann methods.

  12. Highly charged ions as a basis of optical atomic clockwork of exceptional accuracy.

    Science.gov (United States)

    Derevianko, Andrei; Dzuba, V A; Flambaum, V V

    2012-11-02

    We propose a novel class of atomic clocks based on highly charged ions. We consider highly forbidden laser-accessible transitions within the 4f(12) ground-state configurations of highly charged ions. Our evaluation of systematic effects demonstrates that these transitions may be used for building exceptionally accurate atomic clocks which may compete in accuracy with recently proposed nuclear clocks.

  13. The effect of pattern overlap on the accuracy of high resolution electron backscatter diffraction measurements

    Energy Technology Data Exchange (ETDEWEB)

    Tong, Vivian, E-mail: v.tong13@imperial.ac.uk [Department of Materials, Imperial College London, Prince Consort Road, London SW7 2AZ (United Kingdom); Jiang, Jun [Department of Materials, Imperial College London, Prince Consort Road, London SW7 2AZ (United Kingdom); Wilkinson, Angus J. [Department of Materials, University of Oxford, Parks Road, Oxford OX1 3PH (United Kingdom); Britton, T. Ben [Department of Materials, Imperial College London, Prince Consort Road, London SW7 2AZ (United Kingdom)

    2015-08-15

    High resolution, cross-correlation-based, electron backscatter diffraction (EBSD) measures the variation of elastic strains and lattice rotations from a reference state. Regions near grain boundaries are often of interest but overlap of patterns from the two grains could reduce accuracy of the cross-correlation analysis. To explore this concern, patterns from the interior of two grains have been mixed to simulate the interaction volume crossing a grain boundary so that the effect on the accuracy of the cross correlation results can be tested. It was found that the accuracy of HR-EBSD strain measurements performed in a FEG-SEM on zirconium remains good until the incident beam is less than 18 nm from a grain boundary. A simulated microstructure was used to measure how often pattern overlap occurs at any given EBSD step size, and a simple relation was found linking the probability of overlap with step size. - Highlights: • Pattern overlap occurs at grain boundaries and reduces HR-EBSD accuracy. • A test is devised to measure the accuracy of HR-EBSD in the presence of overlap. • High pass filters can sometimes, but not generally, improve HR-EBSD measurements. • Accuracy of HR-EBSD remains high until the reference pattern intensity is <72%. • 9% of points near a grain boundary will have significant error for 200nm step size in Zircaloy-4.

  14. Development of an automatic calibration device for high-accuracy low temperature thermometers

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Based on the analysis and investigation of calibration systems for high-accuracy low temperature thermometers,a new facility for automatic calibration of high-accuracy low temperature thermometers was developed.Continuous calibration for multiple points can be made automatically with this device.According to the thermophysical characteristics of the constant-temperature block in this device,segmented Fuzzy-PID (proportional-integral-differential) algorithm was applied.The experimental results showed that the temperature fluctuation was smaller than ±0.005 K in 30 min.Therefore,this new device can fully meet the calibration requirement of high-precision low temperature thermometers.

  15. Study on High Accuracy Topographic Mapping via UAV-based Images

    Science.gov (United States)

    Chi, Yun-Yao; Lee, Ya-Fen; Tsai, Shang-En

    2016-10-01

    Unmanned aerial vehicle (UAV) provides a promising tool for the acquisition of such multi-temporal aerial stereo photos and high-resolution digital surface models. Recently, the flight of UAVs operates with high degrees of autonomy by the global position system and onboard digit camera and computer. The UAV-based mapping can be obtained faster and cheaper, but its accuracy is anxious. This paper aims to identify the integration ability of high accuracy topographic map via the image of quad-rotors UAV and ground control points (GCPs). The living survey data is collected in the Errn river basins area in Tainan, Taiwan. The high accuracy UAV-based topographic in the study area is calibrated by the local coordinate of GCPs using the total station with the accuracy less than 1/2000. The comparison results show the accuracy of UAV-based topographic is accepted by overlapping. The results can be a reference for the practice works of mapping survey in earth.

  16. Very high-accuracy calibration of radiation pattern and gain of a near-field probe

    DEFF Research Database (Denmark)

    Pivnenko, Sergey; Nielsen, Jeppe Majlund; Breinbjerg, Olav

    2014-01-01

    In this paper, very high-accuracy calibration of the radiation pattern and gain of a near-field probe is described. An open-ended waveguide near-field probe has been used in a recent measurement of the C-band Synthetic Aperture Radar (SAR) Antenna Subsystem for the Sentinel 1 mission of the Europ......In this paper, very high-accuracy calibration of the radiation pattern and gain of a near-field probe is described. An open-ended waveguide near-field probe has been used in a recent measurement of the C-band Synthetic Aperture Radar (SAR) Antenna Subsystem for the Sentinel 1 mission...

  17. [Study on high accuracy detection of multi-component gas in oil-immerse power transformer].

    Science.gov (United States)

    Fan, Jie; Chen, Xiao; Huang, Qi-Feng; Zhou, Yu; Chen, Gang

    2013-12-01

    In order to solve the problem of low accuracy and mutual interference in multi-component gas detection, a kind of multi-component gas detection network with high accuracy was designed. A semiconductor laser with narrow bandwidth was utilized as light source and a novel long-path gas cell was also used in this system. By taking the single sine signal to modulate the spectrum of laser and using space division multiplexing (SDM) and time division multiplexing (TDM) technique, the detection of multi-component gas was achieved. The experiments indicate that the linearity relevance coefficient is 0. 99 and the measurement relative error is less than 4%. The system dynamic response time is less than 15 s, by filling a volume of multi-component gas into the gas cell gradually. The system has advantages of high accuracy and quick response, which can be used in the fault gas on-line monitoring for power transformers in real time.

  18. Analysis of Accuracy of a High-speed Mobile Platform Control System

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The efficient manufacture technique involves a high-speed control of platform mobile system. A linear acutor is presented in this paper. The linear acutor is constructed as a linear stepper motor. However, to sustain both high accuracy and high speed for the position and speed control, A single-stack computer system is constructed and a special control algorithm is prescribed to controled the linear actuator continuously. In this paper, the nonlinear errors resulted from the magnetic saturation and the h...

  19. High-accuracy C-14 measurements for atmospheric CO2 samples by AMS

    NARCIS (Netherlands)

    Meijer, H.A.J.; Pertuisot, M.H.; van der Plicht, J.

    2006-01-01

    In this paper, we investigate how to achieve high-accuracy radiocarbon measurements by accelerator mass spectrometry (ANIS) and present measurement series (performed on archived CO2) of (CO2)-C-14 between 1985 and 1991 for Point Barrow (Alaska) and the South Pole. We report in detail the measurement

  20. Further results on the operation of high-accuracy drift chambers

    NARCIS (Netherlands)

    Breskin, A.; Charpak, G.; Gabioud, B.; Sauli, F.; Trautner, N.

    Optimization of the working parameters in the drift chambers with adjustable electric fields permits stable operation and high accuracies. Full saturation of the drift velocity leads to remarkable improvements, namely a very linear space-time correlation for perpendicular tracks, and simple

  1. From journal to headline: the accuracy of climate science news in Danish high quality newspapers

    DEFF Research Database (Denmark)

    Vestergård, Gunver Lystbæk

    2011-01-01

    analysis to examine the accuracy of Danish high quality newspapers in quoting scientific publications from 1997 to 2009. Out of 88 articles, 46 contained inaccuracies though the majority was found to be insignificant and random. The study concludes that Danish broadsheet newspapers are ‘moderately...

  2. A 1-V 15 μW High-Accuracy Temperature Switch

    NARCIS (Netherlands)

    Schinkel, D.; Boer, de R.P.; Annema, A.J.; Tuijl, van A.J.M.

    2004-01-01

    A CMOS temperature switch with uncalibrated high accuracy is presented. The circuit is based on the classical CMOS bandgap reference structure, using parasitic PNPs and a PTAT multiplier. The circuit was designed in a standard digital 0.18 m CMOS process. The temperature switch has an in-designed hy

  3. From journal to headline: the accuracy of climate science news in Danish high quality newspapers

    DEFF Research Database (Denmark)

    Vestergård, Gunver Lystbæk

    2011-01-01

    analysis to examine the accuracy of Danish high quality newspapers in quoting scientific publications from 1997 to 2009. Out of 88 articles, 46 contained inaccuracies though the majority was found to be insignificant and random. The study concludes that Danish broadsheet newspapers are ‘moderately...

  4. Surgical accuracy in high tibial osteotomy: coronal equivalence of computer navigation and gap measurement.

    Science.gov (United States)

    Schröter, S; Ihle, C; Elson, D W; Döbele, S; Stöckle, U; Ateschrang, A

    2016-11-01

    Medial opening wedge high tibial osteotomy (MOW HTO) is now a successful operation with a range of indications, requiring an individualised approach to the choice of intended correction. This manuscript introduces the concept of surgical accuracy as the absolute deviation of the achieved correction from the intended correction, where small values represent greater accuracy. Surgical accuracy is compared in a randomised controlled trial (RCT) between gap measurement and computer navigation groups. This was a prospective RCT conducted over 3 years of 120 consecutive patients with varus malalignment and medial compartment osteoarthritis, who underwent MOW HTO. All procedures were planned with digital software. Patients were randomly assigned into gap measurement or computer navigation groups. Coronal plane alignment was judged using the mechanical tibiofemoral angle (mTFA), before and after surgery. Absolute (positive) values were calculated for surgical accuracy in each individual case. There was no significant difference in the mean intended correction between groups. The achieved mTFA revealed a small under-correction in both groups. This was attributed to a failure to account for saw blade thickness (gap measurement) and over-compensation for weight bearing (computer navigation). Surgical accuracy was 1.7° ± 1.2° (gap measurement) compared to 2.1° ± 1.4° (computer navigation) without statistical significance. The difference in tibial slope increases of 2.7° ± 3.9° (gap measurement) and 2.1° ± 3.9° (computer navigation) had statistical significance (P osteotomy for individual cases. This work is clinically relevant because coronal surgical accuracy was not superior in either group. Therefore, the increased expense and surgical time associated with navigated MOW HTO is not supported, because meticulously conducted gap measurement yields equivalent surgical accuracy. I.

  5. A high-accuracy surgical augmented reality system using enhanced integral videography image overlay.

    Science.gov (United States)

    Zhang, Xinran; Chen, Guowen; Liao, Hongen

    2015-01-01

    Image guided surgery has been used in clinic to improve the surgery safety and accuracy. Augmented reality (AR) technique, which can provide intuitive image guidance, has been greatly evolved these years. As one promising approach of surgical AR systems, integral videography (IV) autostereoscopic image overlay has achieved accurate fusion of full parallax guidance into surgical scene. This paper describes an image enhanced high-accuracy IV overlay system. A flexible optical image enhancement system (IES) is designed to increase the resolution and quality of IV image. Furthermore, we introduce a novel IV rendering algorithm to promote the spatial accuracy with the consideration of distortion introduced by micro lens array. Preliminary experiments validated that the image accuracy and resolution are improved with the proposed methods. The resolution of the IV image could be promoted to 1 mm for a micro lens array with pitch of 2.32 mm and IES magnification value of 0.5. The relative deviation of accuracy in depth and lateral directions are -4.68 ± 0.83% and -9.01 ± 0.42%.

  6. Horizontal Positional Accuracy of Google Earth's High-Resolution Imagery Archive.

    Science.gov (United States)

    Potere, David

    2008-12-08

    Google Earth now hosts high-resolution imagery that spans twenty percent of the Earth's landmass and more than a third of the human population. This contemporary highresolution archive represents a significant, rapidly expanding, cost-free and largely unexploited resource for scientific inquiry. To increase the scientific utility of this archive, we address horizontal positional accuracy (georegistration) by comparing Google Earth with Landsat GeoCover scenes over a global sample of 436 control points located in 109 cities worldwide. Landsat GeoCover is an orthorectified product with known absolute positional accuracy of less than 50 meters root-mean-squared error (RMSE). Relative to Landsat GeoCover, the 436 Google Earth control points have a positional accuracy of 39.7 meters RMSE (error magnitudes range from 0.4 to 171.6 meters). The control points derived from satellite imagery have an accuracy of 22.8 meters RMSE, which is significantly more accurate than the 48 control-points based on aerial photography (41.3 meters RMSE; t-test p-value Google Earth highresolution imagery has a horizontal positional accuracy that is sufficient for assessing moderate-resolution remote sensing products across most of the world's peri-urban areas.

  7. Determining dynamical parameters of the Milky Way Galaxy based on high-accuracy radio astrometry

    Science.gov (United States)

    Honma, Mareki; Nagayama, Takumi; Sakai, Nobuyuki

    2015-08-01

    In this paper we evaluate how the dynamical structure of the Galaxy can be constrained by high-accuracy VLBI (Very Long Baseline Interferometry) astrometry such as VERA (VLBI Exploration of Radio Astrometry). We generate simulated samples of maser sources which follow the gas motion caused by a spiral or bar potential, with their distribution similar to those currently observed with VERA and VLBA (Very Long Baseline Array). We apply the Markov chain Monte Carlo analyses to the simulated sample sources to determine the dynamical parameter of the models. We show that one can successfully determine the initial model parameters if astrometric results are obtained for a few hundred sources with currently achieved astrometric accuracy. If astrometric data are available from 500 sources, the expected accuracy of R0 and Θ0 is ˜ 1% or higher, and parameters related to the spiral structure can be constrained by an error of 10% or with higher accuracy. We also show that the parameter determination accuracy is basically independent of the locations of resonances such as corotation and/or inner/outer Lindblad resonances. We also discuss the possibility of model selection based on the Bayesian information criterion (BIC), and demonstrate that BIC can be used to discriminate different dynamical models of the Galaxy.

  8. Two-step Structural Design of Mesh Antennas for High Beam Pointing Accuracy

    Science.gov (United States)

    Zhang, Shuxin; Du, Jingli; Wang, Wei; Zhang, Xinghua; Zong, Yali

    2017-05-01

    A well-designed reflector surface with high beam pointing accuracy in electromagnetic performance is of practical significance to the space application of cable mesh reflector antennas. As for space requirements, circular polarizations are widely used in spaceborne antennas, which usually lead to a beam shift for offset reflectors and influence the beam pointing accuracy. A two-step structural design procedure is proposed to overcome the beam squint phenomenon for high beam pointing accuracy design of circularly polarized offset cable mesh reflectors. A simple structural optimal design and an integrated structural electromagnetic optimization are combined to alleviate the beam squint effect of circular polarizations. It is implemented by cable pretension design and adjustment to shape the offset cable mesh surface. Besides, in order to increase the efficiency of integrated optimization, an update Broyden-Fletcher-Goldfarb-Shanno (BFGS) Hessian matrix is employed in the optimization iteration with sequential quadratic programming. A circularly polarized offset cable mesh reflector is utilized to show the feasibility and effectiveness of the proposed procedure. A high beam pointing accuracy in order of 0.0001º of electromagnetic performance is achieved.

  9. The Impact of Ionospheric Disturbances on High Accuracy Positioning in Brazil

    Science.gov (United States)

    Yang, L.; Park, J.; Susnik, A.; Aquino, M. H.; Dodson, A.

    2013-12-01

    High positioning accuracy is a key requirement to a number of applications with a high economic impact, such as precision agriculture, surveying, geodesy, land management, off-shore operations. Global Navigation Satellite Systems (GNSS) carrier phase measurement based techniques, such as Real Time Kinematic (RTK), Network-RTK (NRTK) and Precise Point Positioning (PPP), have played an important role in providing centimetre-level positioning accuracy, and become the core of the above applications. However these techniques are especially sensitive to ionospheric perturbations, in particular scintillation. Brazil sits in one of the most affected regions of the Earth and can be regarded as a test-bed for scenarios of the severe ionospheric condition. Over the Brazilian territory, the ionosphere behaves in a considerably unpredictable way and scintillation activity is very prominent, occurring especially after sunset hours. NRTK services may not be able to provide satisfactory accuracy, or even continuous positioning during strong scintillation periods. CALIBRA (Countering GNSS high Accuracy applications Limitations due to Ionospheric disturbances in BRAzil) started in late 2012 and is a project funded by the GSA (European GNSS Agency) and the European Commission under the Framework Program 7 to deliver improvements on carrier phase based high accuracy algorithms and their implementation in GNSS receivers, aiming to counter the adverse ionospheric effects over Brazil. As the first stage of this project, the ionospheric disturbances, which affect the applications of RTK, NRTK or PPP, are characterized. Typical problems include degraded positioning accuracy, difficulties in ambiguity fixing, NRTK network interpolation errors, long PPP convergence time etc. It will identify how GNSS observables and existing algorithms are degraded by ionosphere related phenomena, evaluating the impact on positioning techniques in terms of accuracy, integrity and availability. Through the

  10. Hybrid head-tracker being examined for the high-accuracy attack rotorcraft market

    Science.gov (United States)

    Blanton, Buddy

    2002-08-01

    The need for the helmet-mounted display (HMD) to present flight, navigation, and weapon information in the pilot's line-of-sight has continued to rise as helicopter missions increase in complexity. To obtain spatial correlation of the direction of the head line-of-sight and pilotage imagery generated from helicopter-mounted sensors, it is necessary to slave the sensors to the head motion. To accomplish this task, a head-tracking system (HTS) must be incorporated into the HMD. There are a variety of techniques that could be applied for locating the position and attitude of a helmet-mounted display. Regardless of the technology, an HTS must provide defined measurements of accuracy. System parameters include motion box size, angular range, pointing angle accuracy, pointing angle resolution, update rate, and slew rate. This paper focuses on a hybrid tracker implementation in which a combination of optical and inertial tracking using strap-down gyros is preferred. Specifically, this tracker implementation is being examined for the high-accuracy attack rotorcraft market which requires a high degree of accuracy. The performance and resultant cost of the tracker components are determined by the specific needs of the intended application. The paper will also indicate how the various requirements drive the cost, configuration, and performance of the resultant hybrid head-tracker.

  11. Literature survey of high-impact journals revealed reporting weaknesses in abstracts of diagnostic accuracy studies.

    Science.gov (United States)

    Korevaar, Daniël A; Cohen, Jérémie F; Hooft, Lotty; Bossuyt, Patrick M M

    2015-06-01

    Informative journal abstracts are crucial for the identification and initial appraisal of studies. We aimed to evaluate the informativeness of abstracts of diagnostic accuracy studies. PubMed was searched for reports of studies that had evaluated the diagnostic accuracy of a test against a clinical reference standard, published in 12 high-impact journals in 2012. Two reviewers independently evaluated the information contained in included abstracts using 21 items deemed important based on published guidance for adequate reporting and study quality assessment. We included 103 abstracts. Crucial information on study population, setting, patient sampling, and blinding as well as confidence intervals around accuracy estimates were reported in items per abstract was 10.1 of 21 (standard deviation 2.2). The mean number of reported items was significantly lower for multiple-gate (case-control type) studies, in reports in specialty journals, and for studies with smaller sample sizes and lower abstract word counts. No significant differences were found between studies evaluating different types of tests. Many abstracts of diagnostic accuracy study reports in high-impact journals are insufficiently informative. Developing guidelines for such abstracts could help the transparency and completeness of reporting. Copyright © 2015 Elsevier Inc. All rights reserved.

  12. About accuracy of the discrimination parameter estimation for the dual high-energy method

    Science.gov (United States)

    Osipov, S. P.; Chakhlov, S. V.; Osipov, O. S.; Shtein, A. M.; Strugovtsev, D. V.

    2015-04-01

    A set of the mathematical formulas to estimate the accuracy of discrimination parameters for two implementations of the dual high energy method - by the effective atomic number and by the level lines is given. The hardware parameters which influenced on the accuracy of the discrimination parameters are stated. The recommendations to form the structure of the high energy X-ray radiation impulses are formulated. To prove the applicability of the proposed procedure there were calculated the statistical errors of the discrimination parameters for the cargo inspection system of the Tomsk polytechnic university on base of the portable betatron MIB-9. The comparison of the experimental estimations and the theoretical ones of the discrimination parameter errors was carried out. It proved the practical applicability of the algorithm to estimate the discrimination parameter errors for the dual high energy method.

  13. High accuracy digital aging monitor based on PLL-VCO circuit

    Science.gov (United States)

    Yuejun, Zhang; Zhidi, Jiang; Pengjun, Wang; Xuelong, Zhang

    2015-01-01

    As the manufacturing process is scaled down to the nanoscale, the aging phenomenon significantly affects the reliability and lifetime of integrated circuits. Consequently, the precise measurement of digital CMOS aging is a key aspect of nanoscale aging tolerant circuit design. This paper proposes a high accuracy digital aging monitor using phase-locked loop and voltage-controlled oscillator (PLL-VCO) circuit. The proposed monitor eliminates the circuit self-aging effect for the characteristic of PLL, whose frequency has no relationship with circuit aging phenomenon. The PLL-VCO monitor is implemented in TSMC low power 65 nm CMOS technology, and its area occupies 303.28 × 298.94 μm2. After accelerating aging tests, the experimental results show that PLL-VCO monitor improves accuracy about high temperature by 2.4% and high voltage by 18.7%.

  14. High accuracy acoustic relative humidity measurement in duct flow with air.

    Science.gov (United States)

    van Schaik, Wilhelm; Grooten, Mart; Wernaart, Twan; van der Geld, Cees

    2010-01-01

    An acoustic relative humidity sensor for air-steam mixtures in duct flow is designed and tested. Theory, construction, calibration, considerations on dynamic response and results are presented. The measurement device is capable of measuring line averaged values of gas velocity, temperature and relative humidity (RH) instantaneously, by applying two ultrasonic transducers and an array of four temperature sensors. Measurement ranges are: gas velocity of 0-12 m/s with an error of ± 0.13 m/s, temperature 0-100 °C with an error of ± 0.07 °C and relative humidity 0-100% with accuracy better than 2 % RH above 50 °C. Main advantage over conventional humidity sensors is the high sensitivity at high RH at temperatures exceeding 50 °C, with accuracy increasing with increasing temperature. The sensors are non-intrusive and resist highly humid environments.

  15. High Mass Accuracy and High Mass Resolving Power FT-ICR Secondary Ion Mass Spectrometry for Biological Tissue Imaging

    CERN Document Server

    Smith, Donald F; Leach, Franklin E; Robinson, Errol W; Paša-Tolić, Ljiljana; Heeren, Ron M A

    2013-01-01

    Biological tissue imaging by secondary ion mass spectrometry has seen rapid development with the commercial availability of polyatomic primary ion sources. Endogenous lipids and other small bio-molecules can now be routinely mapped on the sub-micrometer scale. Such experiments are typically performed on time-of-flight mass spectrometers for high sensitivity and high repetition rate imaging. However, such mass analyzers lack the mass resolving power to ensure separation of isobaric ions and the mass accuracy for elemental formula assignment based on exact mass measurement. We have recently reported a secondary ion mass spectrometer with the combination of a C60 primary ion gun with a Fourier transform ion cyclotron resonance mass spectrometer (FT-ICR MS) for high mass resolving power, high mass measurement accuracy and tandem mass spectrometry capabilities. In this work, high specificity and high sensitivity secondary ion FT-ICR MS was applied to chemical imaging of biological tissue. An entire rat brain tissu...

  16. Results of error correction techniques applied on two high accuracy coordinate measuring machines

    Energy Technology Data Exchange (ETDEWEB)

    Pace, C.; Doiron, T.; Stieren, D.; Borchardt, B.; Veale, R. (Sandia National Labs., Albuquerque, NM (USA); National Inst. of Standards and Technology, Gaithersburg, MD (USA))

    1990-01-01

    The Primary Standards Laboratory at Sandia National Laboratories (SNL) and the Precision Engineering Division at the National Institute of Standards and Technology (NIST) are in the process of implementing software error correction on two nearly identical high-accuracy coordinate measuring machines (CMMs). Both machines are Moore Special Tool Company M-48 CMMs which are fitted with laser positioning transducers. Although both machines were manufactured to high tolerance levels, the overall volumetric accuracy was insufficient for calibrating standards to the levels both laboratories require. The error mapping procedure was developed at NIST in the mid 1970's on an earlier but similar model. The error mapping procedure was originally very complicated and did not make any assumptions about the rigidness of the machine as it moved, each of the possible error motions was measured at each point of the error map independently. A simpler mapping procedure was developed during the early 1980's which assumed rigid body motion of the machine. This method has been used to calibrate lower accuracy machines with a high degree of success and similar software correction schemes have been implemented by many CMM manufacturers. The rigid body model has not yet been used on highly repeatable CMMs such as the M48. In this report we present early mapping data for the two M48 CMMs. The SNL CMM was manufactured in 1985 and has been in service for approximately four years, whereas the NIST CMM was delivered in early 1989. 4 refs., 5 figs.

  17. RNA secondary structure modeling at consistent high accuracy using differential SHAPE.

    Science.gov (United States)

    Rice, Greggory M; Leonard, Christopher W; Weeks, Kevin M

    2014-06-01

    RNA secondary structure modeling is a challenging problem, and recent successes have raised the standards for accuracy, consistency, and tractability. Large increases in accuracy have been achieved by including data on reactivity toward chemical probes: Incorporation of 1M7 SHAPE reactivity data into an mfold-class algorithm results in median accuracies for base pair prediction that exceed 90%. However, a few RNA structures are modeled with significantly lower accuracy. Here, we show that incorporating differential reactivities from the NMIA and 1M6 reagents--which detect noncanonical and tertiary interactions--into prediction algorithms results in highly accurate secondary structure models for RNAs that were previously shown to be difficult to model. For these RNAs, 93% of accepted canonical base pairs were recovered in SHAPE-directed models. Discrepancies between accepted and modeled structures were small and appear to reflect genuine structural differences. Three-reagent SHAPE-directed modeling scales concisely to structurally complex RNAs to resolve the in-solution secondary structure analysis problem for many classes of RNA.

  18. A fast and high accuracy numerical simulation algorithm of the polymer spherulite at the mesoscale Level

    Science.gov (United States)

    Liu, Yongzhi; Geng, Tie; (Tom Turng, Lih-Sheng; Liu, Chuntai; Cao, Wei; Shen, Changyu

    2017-09-01

    In the multiscale numerical simulation of polymer crystallization during the processing period, flow and temperature of the polymer melt are simulated on the macroscale level, while nucleation and growth of the spherulite are simulated at the mesoscale level. As a part of the multiscale simulation, the meso-simulation requires a fast solving speed because the meso-simulation software must be run several times in every macro-element at each macro-step. Meanwhile, the accuracy of the calculation results is also very important. It is known that the simulation geometry of crystallization includes planar (2D) and three-dimensional space (3D). The 3D calculations are more accurate but more expensive because of the long CPU time consumed. On the contrary, 2D calculations are always much faster but lower in accuracy. To reach the desirable speed and high accuracy at the same time, an algorithm is presented, in which the Delesse law coupled with the Monte Carlo method and pixel method are employed to simulate the nucleation, growth, and impingement of the polymer spherulite at the mesoscale level. Based on this algorithm, a software is developed with the Visual C++ language, and its numerical examples’ results prove that the solving speed of this algorithm is as fast as the 2D classical simulation and the calculation accuracy is at the same level as the 3D simulation.

  19. High Accuracy Gravitational Waveforms from Black Hole Binary Inspirals Using OpenCL

    CERN Document Server

    McKennon, Justin; Khanna, Gaurav

    2012-01-01

    There is a strong need for high-accuracy and efficient modeling of extreme-mass-ratio binary black hole systems because these are strong sources of gravitational waves that would be detected by future observatories. In this article, we present sample results from our Teukolsky EMRI code: a time-domain Teukolsky equation solver (a linear, hyperbolic, partial differential equation solver using finite-differencing), that takes advantage of several mathematical and computational enhancements to efficiently generate long-duration and high-accuracy EMRI waveforms. We emphasize here the computational advances made in the context of this code. Currently there is considerable interest in making use of many-core processor architectures, such as Nvidia and AMD graphics processing units (GPUs) for scientific computing. Our code uses the Open Computing Language (OpenCL) for taking advantage of the massive parallelism offered by modern GPU architectures. We present the performance of our Teukolsky EMRI code on multiple mod...

  20. Cavity ring-down technique for measurement of reflectivity of high reflectivity mirrors with high accuracy

    Indian Academy of Sciences (India)

    G Sridhar; Sandeep K Agarwalla; Sunita Singh; L M Gantayet

    2010-12-01

    A simple, accurate and reliable method for measuring the reflectivity of laser-grade mirrors ( > 99.5 %) based on cavity ring-down (CRD) technique has been success-fully demonstrated in our laboratory using a pulsed Nd:YAG laser. A fast photomultiplier tube with an oscilloscope was used to detect and analyse the CRD signal. The cavity decay times were measured for three cavities formed by a combination of three mirror pairs. The absolute reflectivities 1, 2, 3 were determined to be 99.94%, 99.63%, 99.52% at normal incidence. The reflectivity of mirrors is measured to an accuracy of 0.01%.

  1. A Smart High Accuracy Silicon Piezoresistive Pressure Sensor Temperature Compensation System

    Directory of Open Access Journals (Sweden)

    Guanwu Zhou

    2014-07-01

    Full Text Available Theoretical analysis in this paper indicates that the accuracy of a silicon piezoresistive pressure sensor is mainly affected by thermal drift, and varies nonlinearly with the temperature. Here, a smart temperature compensation system to reduce its effect on accuracy is proposed. Firstly, an effective conditioning circuit for signal processing and data acquisition is designed. The hardware to implement the system is fabricated. Then, a program is developed on LabVIEW which incorporates an extreme learning machine (ELM as the calibration algorithm for the pressure drift. The implementation of the algorithm was ported to a micro-control unit (MCU after calibration in the computer. Practical pressure measurement experiments are carried out to verify the system’s performance. The temperature compensation is solved in the interval from −40 to 85 °C. The compensated sensor is aimed at providing pressure measurement in oil-gas pipelines. Compared with other algorithms, ELM acquires higher accuracy and is more suitable for batch compensation because of its higher generalization and faster learning speed. The accuracy, linearity, zero temperature coefficient and sensitivity temperature coefficient of the tested sensor are 2.57% FS, 2.49% FS, 8.1 × 10−5/°C and 29.5 × 10−5/°C before compensation, and are improved to 0.13%FS, 0.15%FS, 1.17 × 10−5/°C and 2.1 × 10−5/°C respectively, after compensation. The experimental results demonstrate that the proposed system is valid for the temperature compensation and high accuracy requirement of the sensor.

  2. High Mass Accuracy and High Mass Resolving Power FT-ICR Secondary Ion Mass Spectrometry for Biological Tissue Imaging

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Donald F.; Kiss, Andras; Leach, Franklin E.; Robinson, Errol W.; Pasa-Tolic, Ljiljana; Heeren, Ronald M.

    2013-07-01

    Biological tissue imaging by secondary ion mass spectrometry has seen rapid development with the commercial availability of polyatomic primary ion sources. Endogenous lipids and other small bio-molecules can now be routinely mapped on the micrometer scale. Such experiments are typically performed on time-of-flight mass spectrometers for high sensitivity and high repetition rate imaging. However, such mass analyzers lack the mass resolving power to ensure separation of isobaric ions and the mass accuracy for exact mass elemental formula assignment. We have recently reported a secondary ion mass spectrometer with the combination of a C60 primary ion gun with a Fourier transform ion cyclotron resonance mass spectrometer (FT-ICR MS) for high mass resolving power, high mass measurement accuracy and tandem mass spectrometry capabilities. In this work, high specificity and high sensitivity secondary ion FT-ICR MS was applied to chemical imaging of biological tissue. An entire rat brain tissue was measured with 150 μm spatial resolution (75 μm primary ion spot size) with mass resolving power (m/Δm50%) of 67,500 (at m/z 750) and root-mean-square measurement accuracy less than two parts-per-million for intact phospholipids, small molecules and fragments. For the first time, ultra-high mass resolving power SIMS has been demonstrated, with m/Δm50% > 3,000,000. Higher spatial resolution capabilities of the platform were tested at a spatial resolution of 20 μm. The results represent order of magnitude improvements in mass resolving power and mass measurement accuracy for SIMS imaging and the promise of the platform for ultra-high mass resolving power and high spatial resolution imaging.

  3. Accuracy of GPS devices for measuring high-intensity running in field-based team sports.

    Science.gov (United States)

    Rampinini, E; Alberti, G; Fiorenza, M; Riggio, M; Sassi, R; Borges, T O; Coutts, A J

    2015-01-01

    We compared the accuracy of 2 GPS systems with different sampling rates for the determination of distances covered at high-speed and metabolic power derived from a combination of running speed and acceleration. 8 participants performed 56 bouts of shuttle intermittent running wearing 2 portable GPS devices (SPI-Pro, GPS-5 Hz and MinimaxX, GPS-10 Hz). The GPS systems were compared with a radar system as a criterion measure. The variables investigated were: total distance (TD), high-speed distance (HSR>4.17 m·s(-1)), very high-speed distance (VHSR>5.56 m·s(-1)), mean power (Pmean), high metabolic power (HMP>20 W·kg(-1)) and very high metabolic power (VHMP>25 W·kg(-1)). GPS-5 Hz had low error for TD (2.8%) and Pmean (4.5%), while the errors for the other variables ranged from moderate to high (7.5-23.2%). GPS-10 Hz demonstrated a low error for TD (1.9%), HSR (4.7%), Pmean (2.4%) and HMP (4.5%), whereas the errors for VHSR (10.5%) and VHMP (6.2%) were moderate. In general, GPS accuracy increased with a higher sampling rate, but decreased with increasing speed of movement. Both systems could be used for calculating TD and Pmean, but they cannot be used interchangeably. Only GPS-10 Hz demonstrated a sufficient level of accuracy for quantifying distance covered at higher speeds or time spent at very high power. © Georg Thieme Verlag KG Stuttgart · New York.

  4. Making high-accuracy null depth measurements for the LBTI exozodi survey

    Science.gov (United States)

    Mennesson, Bertrand; Defrère, Denis; Nowak, Matthias; Hinz, Philip; Millan-Gabet, Rafael; Absil, Olivier; Bailey, Vanessa; Bryden, Geoffrey; Danchi, William; Kennedy, Grant M.; Marion, Lindsay; Roberge, Aki; Serabyn, Eugene; Skemer, Andy J.; Stapelfeldt, Karl; Weinberger, Alycia J.; Wyatt, Mark

    2016-08-01

    The characterization of exozodiacal light emission is both important for the understanding of planetary systems evolution and for the preparation of future space missions aiming to characterize low mass planets in the habitable zone of nearby main sequence stars. The Large Binocular Telescope Interferometer (LBTI) exozodi survey aims at providing a ten-fold improvement over current state of the art, measuring dust emission levels down to a typical accuracy of 12 zodis per star, for a representative ensemble of 30+ high priority targets. Such measurements promise to yield a final accuracy of about 2 zodis on the median exozodi level of the targets sample. Reaching a 1 σ measurement uncertainty of 12 zodis per star corresponds to measuring interferometric cancellation ("null") levels, i.e visibilities at the few 100 ppm uncertainty level. We discuss here the challenges posed by making such high accuracy mid-infrared visibility measurements from the ground and present the methodology we developed for achieving current best levels of 500 ppm or so. We also discuss current limitations and plans for enhanced exozodi observations over the next few years at LBTI.

  5. Optical System Error Analysis and Calibration Method of High-Accuracy Star Trackers

    Directory of Open Access Journals (Sweden)

    Zheng You

    2013-04-01

    Full Text Available The star tracker is a high-accuracy attitude measurement device widely used in spacecraft. Its performance depends largely on the precision of the optical system parameters. Therefore, the analysis of the optical system parameter errors and a precise calibration model are crucial to the accuracy of the star tracker. Research in this field is relatively lacking a systematic and universal analysis up to now. This paper proposes in detail an approach for the synthetic error analysis of the star tracker, without the complicated theoretical derivation. This approach can determine the error propagation relationship of the star tracker, and can build intuitively and systematically an error model. The analysis results can be used as a foundation and a guide for the optical design, calibration, and compensation of the star tracker. A calibration experiment is designed and conducted. Excellent calibration results are achieved based on the calibration model. To summarize, the error analysis approach and the calibration method are proved to be adequate and precise, and could provide an important guarantee for the design, manufacture, and measurement of high-accuracy star trackers.

  6. High Accuracy Attitude Control System Design for Satellite with Flexible Appendages

    Directory of Open Access Journals (Sweden)

    Wenya Zhou

    2014-01-01

    Full Text Available In order to realize the high accuracy attitude control of satellite with flexible appendages, attitude control system consisting of the controller and structural filter was designed. When the low order vibration frequency of flexible appendages is approximating the bandwidth of attitude control system, the vibration signal will enter the control system through measurement device to bring impact on the accuracy or even the stability. In order to reduce the impact of vibration of appendages on the attitude control system, the structural filter is designed in terms of rejecting the vibration of flexible appendages. Considering the potential problem of in-orbit frequency variation of the flexible appendages, the design method for the adaptive notch filter is proposed based on the in-orbit identification technology. Finally, the simulation results are given to demonstrate the feasibility and effectiveness of the proposed design techniques.

  7. High-accuracy determination of the neutron flux at n{sub T}OF

    Energy Technology Data Exchange (ETDEWEB)

    Barbagallo, M.; Colonna, N.; Mastromarco, M.; Meaze, M.; Tagliente, G.; Variale, V. [Sezione di Bari, INFN, Bari (Italy); Guerrero, C.; Andriamonje, S.; Boccone, V.; Brugger, M.; Calviani, M.; Cerutti, F.; Chin, M.; Ferrari, A.; Kadi, Y.; Losito, R.; Versaci, R.; Vlachoudis, V. [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Tsinganis, A. [European Organization for Nuclear Research (CERN), Geneva (Switzerland); National Technical University of Athens (NTUA), Athens (Greece); Tarrio, D.; Duran, I.; Leal-Cidoncha, E.; Paradela, C. [Universidade de Santiago de Compostela, Santiago (Spain); Altstadt, S.; Goebel, K.; Langer, C.; Reifarth, R.; Schmidt, S.; Weigand, M. [Johann-Wolfgang-Goethe Universitaet, Frankfurt (Germany); Andrzejewski, J.; Marganiec, J.; Perkowski, J. [Uniwersytet Lodzki, Lodz (Poland); Audouin, L.; Leong, L.S.; Tassan-Got, L. [Centre National de la Recherche Scientifique/IN2P3 - IPN, Orsay (France); Becares, V.; Cano-Ott, D.; Garcia, A.R.; Gonzalez-Romero, E.; Martinez, T.; Mendoza, E. [Centro de Investigaciones Energeticas Medioambientales y Tecnologicas (CIEMAT), Madrid (Spain); Becvar, F.; Krticka, M.; Kroll, J.; Valenta, S. [Charles University, Prague (Czech Republic); Belloni, F.; Fraval, K.; Gunsing, F.; Lampoudis, C.; Papaevangelou, T. [Commissariata l' Energie Atomique (CEA) Saclay - Irfu, Gif-sur-Yvette (France); Berthoumieux, E.; Chiaveri, E. [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Commissariata l' Energie Atomique (CEA) Saclay - Irfu, Gif-sur-Yvette (France); Billowes, J.; Ware, T.; Wright, T. [University of Manchester, Manchester (United Kingdom); Bosnar, D.; Zugec, P. [University of Zagreb, Department of Physics, Faculty of Science, Zagreb (Croatia); Calvino, F.; Cortes, G.; Gomez-Hornillos, M.B.; Riego, A. [Universitat Politecnica de Catalunya, Barcelona (Spain); Carrapico, C.; Goncalves, I.F.; Sarmento, R.; Vaz, P. [Universidade Tecnica de Lisboa, Instituto Tecnologico e Nuclear, Instituto Superior Tecnico, Lisboa (Portugal); Cortes-Giraldo, M.A.; Praena, J.; Quesada, J.M.; Sabate-Gilarte, M. [Universidad de Sevilla, Sevilla (Spain); Diakaki, M.; Karadimos, D.; Kokkoris, M.; Vlastou, R. [National Technical University of Athens (NTUA), Athens (Greece); Domingo-Pardo, C.; Giubrone, G.; Tain, J.L. [CSIC-Universidad de Valencia, Instituto de Fisica Corpuscular, Valencia (Spain); Dressler, R.; Kivel, N.; Schumann, D.; Steinegger, P. [Paul Scherrer Institut, Villigen PSI (Switzerland); Dzysiuk, N.; Mastinu, P.F. [Laboratori Nazionali di Legnaro, INFN, Rome (Italy); Eleftheriadis, C.; Manousos, A. [Aristotle University of Thessaloniki, Thessaloniki (Greece); Ganesan, S.; Gurusamy, P.; Saxena, A. [Bhabha Atomic Research Centre (BARC), Mumbai (IN); Griesmayer, E.; Jericha, E.; Leeb, H. [Technische Universitaet Wien, Atominstitut, Wien (AT); Hernandez-Prieto, A. [European Organization for Nuclear Research (CERN), Geneva (CH); Universitat Politecnica de Catalunya, Barcelona (ES); Jenkins, D.G.; Vermeulen, M.J. [University of York, Heslington, York (GB); Kaeppeler, F. [Institut fuer Kernphysik, Karlsruhe Institute of Technology, Campus Nord, Karlsruhe (DE); Koehler, P. [Oak Ridge National Laboratory (ORNL), Oak Ridge (US); Lederer, C. [Johann-Wolfgang-Goethe Universitaet, Frankfurt (DE); University of Vienna, Faculty of Physics, Vienna (AT); Massimi, C.; Mingrone, F.; Vannini, G. [Universita di Bologna (IT); INFN, Sezione di Bologna, Dipartimento di Fisica, Bologna (IT); Mengoni, A.; Ventura, A. [Agenzia nazionale per le nuove tecnologie, l' energia e lo sviluppo economico sostenibile (ENEA), Bologna (IT); Milazzo, P.M. [Sezione di Trieste, INFN, Trieste (IT); Mirea, M. [Horia Hulubei National Institute of Physics and Nuclear Engineering - IFIN HH, Bucharest - Magurele (RO); Mondalaers, W.; Plompen, A.; Schillebeeckx, P. [Institute for Reference Materials and Measurements, European Commission JRC, Geel (BE); Pavlik, A.; Wallner, A. [University of Vienna, Faculty of Physics, Vienna (AT); Rauscher, T. [University of Basel, Department of Physics and Astronomy, Basel (CH); Roman, F. [European Organization for Nuclear Research (CERN), Geneva (CH); Horia Hulubei National Institute of Physics and Nuclear Engineering - IFIN HH, Bucharest - Magurele (RO); Rubbia, C. [European Organization for Nuclear Research (CERN), Geneva (CH); Laboratori Nazionali del Gran Sasso dell' INFN, Assergi (AQ) (IT); Weiss, C. [European Organization for Nuclear Research (CERN), Geneva (CH); Johann-Wolfgang-Goethe Universitaet, Frankfurt (DE)

    2013-12-15

    The neutron flux of the n{sub T}OF facility at CERN was measured, after installation of the new spallation target, with four different systems based on three neutron-converting reactions, which represent accepted cross sections standards in different energy regions. A careful comparison and combination of the different measurements allowed us to reach an unprecedented accuracy on the energy dependence of the neutron flux in the very wide range (thermal to 1 GeV) that characterizes the n{sub T}OF neutron beam. This is a pre-requisite for the high accuracy of cross section measurements at n{sub T}OF. An unexpected anomaly in the neutron-induced fission cross section of {sup 235}U is observed in the energy region between 10 and 30keV, hinting at a possible overestimation of this important cross section, well above currently assigned uncertainties. (orig.)

  8. Navigation Facility for High Accuracy Offline Trajectory and Attitude Estimation in Airborne Applications

    Directory of Open Access Journals (Sweden)

    A. Renga

    2013-01-01

    Full Text Available The paper focuses on a navigation facility, relying on commercial-off-the-shelf (COTS technology, developed to generate high-accuracy attitude and trajectory measurements in postprocessing. Target performance is cm-level positioning with tenth of degree attitude accuracy. The facility is based on the concept of GPS-aided inertial navigation but comprises carrier-phase differential GPS (CDGPS processing and attitude estimation based on multiantenna GPS configurations. Expected applications of the system include: (a performance assessment of integrated navigation systems, developed for general aviation aircraft and medium size unmanned aircraft systems (UAS; (b generation of reference measurements to evaluate the flight performance of airborne sensors (e.g., radar or laser; and (c generation of reference trajectory and attitude for improving imaging quality of airborne remote sensing data. The paper describes system architecture, selected algorithms for data processing and integration, and theoretical performance evaluation. Experimental results are also presented confirming the effectiveness of the implemented approach.

  9. High-Accuracy Elevation Data at Large Scales from Airborne Single-Pass SAR Interferometry

    Directory of Open Access Journals (Sweden)

    Guy Jean-Pierre Schumann

    2016-01-01

    Full Text Available Digital elevation models (DEMs are essential data sets for disaster risk management and humanitarian relief services as well as many environmental process models. At present, on the hand, globally available DEMs only meet the basic requirements and for many services and modeling studies are not of high enough spatial resolution and lack accuracy in the vertical. On the other hand, LiDAR-DEMs are of very high spatial resolution and great vertical accuracy but acquisition operations can be very costly for spatial scales larger than a couple of hundred square km and also have severe limitations in wetland areas and under cloudy and rainy conditions. The ideal situation would thus be to have a DEM technology that allows larger spatial coverage than LiDAR but without compromising resolution and vertical accuracy and still performing under some adverse weather conditions and at a reasonable cost. In this paper, we present a novel single pass In-SAR technology for airborne vehicles that is cost-effective and can generate DEMs with a vertical error of around 0.3 m for an average spatial resolution of 3 m. To demonstrate this capability, we compare a sample single-pass In-SAR Ka-band DEM of the California Central Valley from the NASA/JPL airborne GLISTIN-A to a high-resolution LiDAR DEM. We also perform a simple sensitivity analysis to floodplain inundation. Based on the findings of our analysis, we argue that this type of technology can and should be used to replace large regions of globally available lower resolution DEMs, particularly in coastal, delta and floodplain areas where a high number of assets, habitats and lives are at risk from natural disasters. We conclude with a discussion on requirements, advantages and caveats in terms of instrument and data processing.

  10. High-Accuracy Elevation Data at Large Scales from Airborne Single-Pass SAR Interferometry

    Science.gov (United States)

    Schumann, Guy; Moller, Delwyn; Mentgen, Felix

    2015-12-01

    Digital elevation models (DEMs) are essential data sets for disaster risk management and humanitarian relief services as well as many environmental process models. At present, on the hand, globally available DEMs only meet the basic requirements and for many services and modeling studies are not of high enough spatial resolution and lack accuracy in the vertical. On the other hand, LiDAR-DEMs are of very high spatial resolution and great vertical accuracy but acquisition operations can be very costly for spatial scales larger than a couple of hundred square km and also have severe limitations in wetland areas and under cloudy and rainy conditions. The ideal situation would thus be to have a DEM technology that allows larger spatial coverage than LiDAR but without compromising resolution and vertical accuracy and still performing under some adverse weather conditions and at a reasonable cost. In this paper, we present a novel single pass In-SAR technology for airborne vehicles that is cost-effective and can generate DEMs with a vertical error of around 0.3 m for an average spatial resolution of 3 m. To demonstrate this capability, we compare a sample single-pass In-SAR Ka-band DEM of the California Central Valley from the NASA/JPL airborne GLISTIN-A to a high-resolution LiDAR DEM. We also perform a simple sensitivity analysis to floodplain inundation. Based on the findings of our analysis, we argue that this type of technology can and should be used to replace large regions of globally available lower resolution DEMs, particularly in coastal, delta and floodplain areas where a high number of assets, habitats and lives are at risk from natural disasters. We conclude with a discussion on requirements, advantages and caveats in terms of instrument and data processing.

  11. SNP-based non-invasive prenatal testing detects sex chromosome aneuploidies with high accuracy

    Science.gov (United States)

    Samango-Sprouse, Carole; Banjevic, Milena; Ryan, Allison; Sigurjonsson, Styrmir; Zimmermann, Bernhard; Hill, Matthew; Hall, Megan P.; Westemeyer, Margaret; Saucier, Jennifer; Demko, Zachary; Rabinowitz, Matthew

    2013-01-01

    Objective To develop a single nucleotide polymorphism- and informatics-based non-invasive prenatal test that detects sex chromosome aneuploidies early in pregnancy. Methods Fifteen aneuploid samples, including thirteen 45,X, two 47,XXY, and one 47,XYY, along with 185 euploid controls, were analyzed. Cell-free DNA was isolated from maternal plasma, amplified in a single multiplex PCR assay that targeted 19,488 polymorphic loci covering chromosomes 13, 18, 21, X, and Y, and sequenced. Sequencing results were analyzed using a Bayesian-based maximum likelihood statistical method to determine copy number of interrogated chromosomes, calculating sample-specific accuracies. Results Of the samples that passed a stringent quality control metric (93%), the algorithm correctly identified copy number at all five chromosomes in all 187 samples, for 934/935 correct calls as early as 9.4 weeks of gestation. We detected 45,X with 91.7% sensitivity (CI: 61.5-99.8%) and 100% specificity (CI: 97.9-100%), and 47,XXY and 47,XYY. The average calculated accuracy was 99.78%. Conclusion This method non-invasively detected 45,X, 47,XXY, and 47,XYY fetuses from cfDNA isolated from maternal plasma with high calculated accuracies, and thus offers a non-invasive method with the potential to function as a routine screen allowing for early prenatal detection of rarely diagnosed yet commonly occurring sex aneuploidies. PMID:23712453

  12. High-accuracy defect sizing for nozzle attachment welds using asymmetric TOFD

    Energy Technology Data Exchange (ETDEWEB)

    Bloodworth, T. [AEA Technology, Risley (United Kingdom)

    1999-09-01

    Inspection procedures for the detection, characterisation and high-accuracy sizing of defects in nozzle attachment welds in a Swedish BWR have been developed. These welds are set-on nozzle-to-pipe attachment welds between the main recirculation pipe and related piping systems. The nozzles and the main recirculation pipe are made of ferritic steel with austenitic stainless steel cladding on the inner surface. The overall wall thickness of the nozzle is 30 mm. The inspection uses an automated pulse-echo technique for the detection and length sizing of defects. Software for the display of complex geometry ultrasonic data is used to assist in data analysis. An unorthodox automated ultrasonic TOFD technique is used to measure the through-wall height of defects. This technique deploys probes on both the nozzle and main pipe surfaces. The TOFD data for this complex geometry are analysed using the CGTOFD software, to locate the origin of defect edge signals. The Qualification detection criterion for this inspection is the detection of defects 6 mm x 18 mm (height x length) or greater. The required length measurement accuracy is {+-}14 mm and the required through-wall height measurement accuracy is {+-}2.3 mm. This last requirement is very demanding. The inspection procedures for detection and sizing passed Procedure Qualification when measured against the above criteria on an `open` test specimen. Data collection and analysis personnel have subsequently passed Personnel Qualification using `blind` specimens. (Author)

  13. Uncertainty and target accuracy studies for the very high temperature reactor(VHTR) physics parameters.

    Energy Technology Data Exchange (ETDEWEB)

    Taiwo, T. A.; Palmiotti, G.; Aliberti, G.; Salvatores, M.; Kim, T.K.

    2005-09-16

    The potential impact of nuclear data uncertainties on a number of performance parameters (core and fuel cycle) of the prismatic block-type Very High Temperature Reactor (VHTR) has been evaluated and results are presented in this report. An uncertainty analysis has been performed, based on sensitivity theory, which underlines what cross-sections, what energy range and what isotopes are responsible for the most significant uncertainties. In order to give guidelines on priorities for new evaluations or validation experiments, required accuracies on specific nuclear data have been derived, accounting for target accuracies on major design parameters. Results of an extensive analysis indicate only a limited number of relevant parameters do not meet the target accuracies assumed in this work; this does not imply that the existing nuclear cross-section data cannot be used for the feasibility and pre-conceptual assessments of the VHTR. However, the results obtained depend on the uncertainty data used, and it is suggested to focus some future evaluation work on the production of consistent, as far as possible complete and user oriented covariance data.

  14. High accuracy measurements of magnetic field integrals for the european XFEL undulator systems

    Science.gov (United States)

    Wolff-Fabris, Frederik; Viehweger, Marc; Li, Yuhui; Pflüger, Joachim

    2016-10-01

    Two high accuracy moving wire (MW) measurement systems based on stretched wire technique were built for the European XFEL (XFEL.EU). They were dedicated to monitor, tune and improve the magnetic field integrals properties during the serial production of the undulator segments, phase shifters and air coil correctors for XFEL.EU. For the magnetic tuning of phase shifters and the calibration of the air coils correctors a short portable MW measurement bench was built to measure first field integrals in short devices with magnetic length of less than about 300 mm and with an ultimate accuracy much better than 1 G cm (0.001 T mm). A long MW measurement setup was dedicated to obtain the total first and second field integrals on the 5-meters long undulator segments with accuracy of about 4 G cm (0.004 T mm) and 2000 G cm2 (20 T mm2) for the 1st and 2nd field integrals, respectively. Using these data a method was developed to compute the proper corrections for the air coils correctors used at both extremities so that zero first and second field integrals for an undulator segment are obtained. It is demonstrated that charging air coils correctors with these corrections results in near zero effect to the electron trajectory in the undulator systems and consequently no negative impact on the self-amplified spontaneous emission (SASE) process should occur.

  15. Accuracy assessment of high frequency 3D ultrasound for digital impression-taking of prepared teeth

    Science.gov (United States)

    Heger, Stefan; Vollborn, Thorsten; Tinschert, Joachim; Wolfart, Stefan; Radermacher, Klaus

    2013-03-01

    Silicone based impression-taking of prepared teeth followed by plaster casting is well-established but potentially less reliable, error-prone and inefficient, particularly in combination with emerging techniques like computer aided design and manufacturing (CAD/CAM) of dental prosthesis. Intra-oral optical scanners for digital impression-taking have been introduced but until now some drawbacks still exist. Because optical waves can hardly penetrate liquids or soft-tissues, sub-gingival preparations still need to be uncovered invasively prior to scanning. High frequency ultrasound (HFUS) based micro-scanning has been recently investigated as an alternative to optical intra-oral scanning. Ultrasound is less sensitive against oral fluids and in principal able to penetrate gingiva without invasively exposing of sub-gingival preparations. Nevertheless, spatial resolution as well as digitization accuracy of an ultrasound based micro-scanning system remains a critical parameter because the ultrasound wavelength in water-like media such as gingiva is typically smaller than that of optical waves. In this contribution, the in-vitro accuracy of ultrasound based micro-scanning for tooth geometry reconstruction is being investigated and compared to its extra-oral optical counterpart. In order to increase the spatial resolution of the system, 2nd harmonic frequencies from a mechanically driven focused single element transducer were separated and corresponding 3D surface models were calculated for both fundamentals and 2nd harmonics. Measurements on phantoms, model teeth and human teeth were carried out for evaluation of spatial resolution and surface detection accuracy. Comparison of optical and ultrasound digital impression taking indicate that, in terms of accuracy, ultrasound based tooth digitization can be an alternative for optical impression-taking.

  16. A High-Performance Operational Amplifier for High-Speed High-Accuracy Switch-Capacitor Cells

    Institute of Scientific and Technical Information of China (English)

    Qi Fan; Ning Ning; Qi Yu; Da Chen

    2007-01-01

    A highspeed highaccuracy fully differenttial operational amplifier (opamp) is realized based on noMillercapacitor feedforward (NMCF) compensation scheme. In order to achieve a good phase margin, the NMCF compensation scheme uses the positive phase shift of lefthalfplane (LHP) zero caused by the feedforward path to counteract the negative phase shift of the nondominant pole. Compared to traditional Miller compensation method, the opamp obtains high gain and wide band synchronously without the polesplitting effect while saves significant chip area due to the absence of the Miller capacitor. Simulated by the 0.35 μm CMOS RF technology, the result shows that the openloop gain of the opamp is 118 dB with the unity gainbandwidth (UGBW)of 1 GHz, and the phase margin is 61°while the settling time is 5.8 ns when achieving 0.01% accuracy. The opamp is especially suitable for the frontend sample/hold (S/H)cell and the multiplying D/A converter(MDAC) module of the highspeed highresolution pipelined A/D converters(ADCs).

  17. Ultra-high accuracy optical testing: creating diffraction-limitedshort-wavelength optical systems

    Energy Technology Data Exchange (ETDEWEB)

    Goldberg, Kenneth A.; Naulleau, Patrick P.; Rekawa, Senajith B.; Denham, Paul E.; Liddle, J. Alexander; Gullikson, Eric M.; Jackson, KeithH.; Anderson, Erik H.; Taylor, John S.; Sommargren, Gary E.; Chapman,Henry N.; Phillion, Donald W.; Johnson, Michael; Barty, Anton; Soufli,Regina; Spiller, Eberhard A.; Walton, Christopher C.; Bajt, Sasa

    2005-08-03

    Since 1993, research in the fabrication of extreme ultraviolet (EUV) optical imaging systems, conducted at Lawrence Berkeley National Laboratory (LBNL) and Lawrence Livermore National Laboratory (LLNL), has produced the highest resolution optical systems ever made. We have pioneered the development of ultra-high-accuracy optical testing and alignment methods, working at extreme ultraviolet wavelengths, and pushing wavefront-measuring interferometry into the 2-20-nm wavelength range (60-600 eV). These coherent measurement techniques, including lateral shearing interferometry and phase-shifting point-diffraction interferometry (PS/PDI) have achieved RMS wavefront measurement accuracies of 0.5-1-{angstrom} and better for primary aberration terms, enabling the creation of diffraction-limited EUV optics. The measurement accuracy is established using careful null-testing procedures, and has been verified repeatedly through high-resolution imaging. We believe these methods are broadly applicable to the advancement of short-wavelength optical systems including space telescopes, microscope objectives, projection lenses, synchrotron beamline optics, diffractive and holographic optics, and more. Measurements have been performed on a tunable undulator beamline at LBNL's Advanced Light Source (ALS), optimized for high coherent flux; although many of these techniques should be adaptable to alternative ultraviolet, EUV, and soft x-ray light sources. To date, we have measured nine prototype all-reflective EUV optical systems with NA values between 0.08 and 0.30 (f/6.25 to f/1.67). These projection-imaging lenses were created for the semiconductor industry's advanced research in EUV photolithography, a technology slated for introduction in 2009-13. This paper reviews the methods used and our program's accomplishments to date.

  18. High Accuracy, Two-Dimensional Read-Out in Multiwire Proportional Chambers

    Science.gov (United States)

    Charpak, G.; Sauli, F.

    1973-02-14

    In most applications of proportional chambers, especially in high-energy physics, separate chambers are used for measuring different coordinates. In general one coordinate is obtained by recording the pulses from the anode wires around which avalanches have grown. Several methods have been imagined for obtaining the position of an avalanche along a wire. In this article a method is proposed which leads to the same range of accuracies and may be preferred in some cases. The problem of accurate measurements for large-size chamber is also discussed.

  19. High-accuracy thickness measurement of a transparent plate with the heterodyne central fringe identification technique

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Wang-Tsung; Hsieh, Hung-Chih; Chang, Wei-Yao; Chen, Yen-Liang; Su, Der-Chin

    2011-07-20

    In a modified Twyman-Green interferometer, the optical path variation is measured with the heterodyne central fringe identification technique, as the light beam is focused by a displaced microscopic objective on the front/rear surface of the test transparent plate. The optical path length variation is then measured similarly after the test plate is removed. The geometrical thickness of the test plate can be calculated under the consideration of dispersion effect. This method has a wide measurable range and a high accuracy in the measurable range.

  20. A small and high accuracy gyro stabilization electro-optical platform

    Science.gov (United States)

    Qiu, Haitao; Han, Yonggen; Lv, Yanhong

    2008-10-01

    A high accuracy line-of-sight (LOS) Stabilization system based on digital control technology was designed. The current feedback closed-loop system was introduced which uses the CCD graphic and resolver to constitute the position closed-loop and uses the optic fiber gyro to constitute the rate closed-loop. In order to realize zero steady-state error of angular output in counteracting disturbance from carrier, a PII2 (proportional-integral-double integral) control scheme is proposed. The hardware configuration and software system is presented. Experimental results show that the system has perfect dynamic and static performance and the technical requirements were satisfied.

  1. High Accuracy Three-dimensional Simulation of Micro Injection Moulded Parts

    DEFF Research Database (Denmark)

    Tosello, Guido; Costa, F. S.; Hansen, Hans Nørgaard

    2011-01-01

    Micro injection moulding (μIM) is the key replication technology for high precision manufacturing of polymer micro products. Data analysis and simulations on micro-moulding experiments have been conducted during the present validation study. Detailed information about the μIM process was gathered...... and used to establish a reliable simulation methodology suitable for μIM parts. Various Simulation set-up parameters that have been considered in order to improve the simulation accuracy: injection speed profile, melt and mould temperatures, 3D mesh, material rheology, inertia effect and shrinkage...

  2. High-accuracy mass determination of unstable nuclei with a Penning trap mass spectrometer

    CERN Multimedia

    2002-01-01

    The mass of a nucleus is its most fundamental property. A systematic study of nuclear masses as a function of neutron and proton number allows the observation of collective and single-particle effects in nuclear structure. Accurate mass data are the most basic test of nuclear models and are essential for their improvement. This is especially important for the astrophysical study of nuclear synthesis. In order to achieve the required high accuracy, the mass of ions captured in a Penning trap is determined via their cyclotron frequency $ \

  3. An angle encoder for super-high resolution and super-high accuracy using SelfA

    Science.gov (United States)

    Watanabe, Tsukasa; Kon, Masahito; Nabeshima, Nobuo; Taniguchi, Kayoko

    2014-06-01

    Angular measurement technology at high resolution for applications such as in hard disk drive manufacturing machines, precision measurement equipment and aspherical process machines requires a rotary encoder with high accuracy, high resolution and high response speed. However, a rotary encoder has angular deviation factors during operation due to scale error or installation error. It has been assumed to be impossible to achieve accuracy below 0.1″ in angular measurement or control after the installation onto the rotating axis. Self-calibration (Lu and Trumper 2007 CIRP Ann. 56 499; Kim et al 2011 Proc. MacroScale; Probst 2008 Meas. Sci. Technol. 19 015101; Probst et al Meas. Sci. Technol. 9 1059; Tadashi and Makoto 1993 J. Robot. Mechatronics 5 448; Ralf et al 2006 Meas. Sci. Technol. 17 2811) and cross-calibration (Probst et al 1998 Meas. Sci. Technol. 9 1059; Just et al 2009 Precis. Eng. 33 530; Burnashev 2013 Quantum Electron. 43 130) technologies for a rotary encoder have been actively discussed on the basis of the principle of circular closure. This discussion prompted the development of rotary tables which achieve reliable and high accuracy angular verification. We apply these technologies for the development of a rotary encoder not only to meet the requirement of super-high accuracy but also to meet that of super-high resolution. This paper presents the development of an encoder with 221 = 2097 152 resolutions per rotation (360°), that is, corresponding to a 0.62″ signal period, achieved by the combination of a laser rotary encoder supplied by Magnescale Co., Ltd and a self-calibratable encoder (SelfA) supplied by The National Institute of Advanced Industrial Science & Technology (AIST). In addition, this paper introduces the development of a rotary encoder to guarantee ±0.03″ accuracy at any point of the interpolated signal, with respect to the encoder at the minimum resolution of 233, that is, corresponding to a 0.0015″ signal period after

  4. High-accuracy current sensing circuit with current compensation technique for buck-boost converter

    Science.gov (United States)

    Rao, Yuan; Deng, Wan-Ling; Huang, Jun-Kai

    2015-03-01

    A novel on-chip current sensing circuit with current compensation technique suitable for buck-boost converter is presented in this article. The proposed technique can sense the full-range inductor current with high accuracy and high speed. It is mainly based on matched current mirror and does not require a large proportion of aspect ratio between the powerFET and the senseFET, thus it reduces the complexity of circuit design and the layout mismatch issue without decreasing the power efficiency. The circuit is fabricated with TSMC 0.25 µm 2P5M mixed-signal process. Simulation results show that the buck-boost converter can be operated at 200 kHz to 4 MHz switching frequency with an input voltage from 2.8 to 4.7 V. The output voltage is 3.6 V, and the maximum accuracy for both high and low side sensing current reaches 99% within the load current ranging from 200 to 600 mA.

  5. Simple high-accuracy resolution program for convective modelling of discontinuities

    Science.gov (United States)

    Leonard, B. P.

    1988-01-01

    For steady multidimensional convection, the Quadratic Upstream Interpolation for Convective Kinematics (QUICK) scheme has several attractive properties. However, for highly convective simulation of step profiles, QUICK produces unphysical overshoots and a few oscillations, and this may cause serious problems in nonlinear flows. Fortunately, it is possible to modify the convective flux by writing the normalized convected control-volume face value as a function of the normalized adjacent upstream node value, developing criteria for monotonic resolution without sacrificing formal accuracy. This results in a nonlinear functional relationship between the normalized variables, whereas standard methods are all linear in this sense. The resulting Simple High Accuracy Resolution Program (SHARP) can be applied to steady multidimensional flows containing thin shear or mixing layers, shock waves, and other frontal phenomena. This represents a significant advance in modeling highly convective flows of engineering and geophysical importance. SHARP is based on an explicit, conservative, control-volume flux formation, equally applicable to one, two, or three dimensional elliptic, parabolic, hyperbolic, or mixed-flow regimes. Results are given for the bench-mark purely convective first-order results and the nonmonotonic predictions of second- and third-order upwinding.

  6. High-accuracy optimal finite-thrust trajectories for Moon escape

    Science.gov (United States)

    Shen, Hong-Xin; Casalino, Lorenzo

    2017-02-01

    The optimization problem of fuel-optimal trajectories from a low circular Moon orbit to a target hyperbolic excess velocity vector using finite-thrust propulsion is solved. The ability to obtain the most accurate satisfaction of necessary optimality conditions in a high-accuracy dynamic model is the main motivation of the current study. The solutions allow attaining anytime-return Earth-interface conditions from a low lunar orbit. Gravitational effects of the Sun, Earth, and Moon are included throughout the entire trajectory. Severe constraints on the fuel budget combined with high-accuracy demands on the endpoint conditions necessitate a high-fidelity solution to the trajectory optimization problem and JPL DE405 ephemeris model is used to determine the perturbing bodies' positions. The optimization problem is solved using an indirect method. The optimality of the solution is verified by an application of Pontryagin's maximum principle. More accurate and fuel-efficient trajectories are found for the same mission objectives and constraints published in other research, emphasizing the advantages of this technique. It is also shown that the thrust structure consists of three finite burns. In contrast to previous research, no singular arc is required in the optimal solutions, and all the controls appear bang-bang.

  7. Emergency positioning system accuracy with infrared LEDs in high-security facilities

    Science.gov (United States)

    Knoch, Sierra N.; Nelson, Charles; Walker, Owens

    2017-05-01

    Instantaneous personnel location presents a challenge in Department of Defense applications where high levels of security restrict real-time tracking of crew members. During emergency situations, command and control requires immediate accountability of all personnel. Current radio frequency (RF) based indoor positioning systems can be unsuitable due to RF leakage and electromagnetic interference with sensitively calibrated machinery on variable platforms like ships, submarines and high-security facilities. Infrared light provide a possible solution to this problem. This paper proposes and evaluates an indoor line-of-sight positioning system that is comprised of IR and high-sensitivity CMOS camera receivers. In this system the movement of the LEDs is captured by the camera, uploaded and analyzed; the highest point of power is located and plotted to create a blueprint of crewmember location. Results provided evaluate accuracy as a function of both wavelength and environmental conditions. Research will further evaluate the accuracy of the LED transmitter and CMOS camera receiver system. Transmissions in both the 780 and 850nm IR are analyzed.

  8. High accuracy genotyping directly from genomic DNA using a rolling circle amplification based assay

    Directory of Open Access Journals (Sweden)

    Du Yuefen

    2003-05-01

    Full Text Available Abstract Background Rolling circle amplification of ligated probes is a simple and sensitive means for genotyping directly from genomic DNA. SNPs and mutations are interrogated with open circle probes (OCP that can be circularized by DNA ligase when the probe matches the genotype. An amplified detection signal is generated by exponential rolling circle amplification (ERCA of the circularized probe. The low cost and scalability of ligation/ERCA genotyping makes it ideally suited for automated, high throughput methods. Results A retrospective study using human genomic DNA samples of known genotype was performed for four different clinically relevant mutations: Factor V Leiden, Factor II prothrombin, and two hemochromatosis mutations, C282Y and H63D. Greater than 99% accuracy was obtained genotyping genomic DNA samples from hundreds of different individuals. The combined process of ligation/ERCA was performed in a single tube and produced fluorescent signal directly from genomic DNA in less than an hour. In each assay, the probes for both normal and mutant alleles were combined in a single reaction. Multiple ERCA primers combined with a quenched-peptide nucleic acid (Q-PNA fluorescent detection system greatly accellerated the appearance of signal. Probes designed with hairpin structures reduced misamplification. Genotyping accuracy was identical from either purified genomic DNA or genomic DNA generated using whole genome amplification (WGA. Fluorescent signal output was measured in real time and as an end point. Conclusions Combining the optimal elements for ligation/ERCA genotyping has resulted in a highly accurate single tube assay for genotyping directly from genomic DNA samples. Accuracy exceeded 99 % for four probe sets targeting clinically relevant mutations. No genotypes were called incorrectly using either genomic DNA or whole genome amplified sample.

  9. Discovery and validation of urine markers of acute pediatric appendicitis using high accuracy mass spectrometry

    Science.gov (United States)

    Kentsis, Alex; Lin, Yin Yin; Kurek, Kyle; Calicchio, Monica; Wang, Yan Yan; Monigatti, Flavio; Campagne, Fabien; Lee, Richard; Horwitz, Bruce; Steen, Hanno; Bachur, Richard

    2015-01-01

    Study Objective Molecular definition of disease has been changing all aspects of medical practice, from diagnosis and screening to understanding and treatment. Acute appendicitis is among many human conditions that are complicated by the heterogeneity of clinical presentation and shortage of diagnostic markers. Here, we sought to profile the urine of patients with appendicitis with the goal of identifying new diagnostic markers. Methods Candidate markers were identified from the urine of children with histologically proven appendicitis by using high accuracy mass spectrometry proteome profiling. These systemic and local markers were used to assess the probability of appendicitis in a blinded, prospective study of children being evaluated for acute abdominal pain in our emergency department. Tests of performance of the markers were evaluated against the pathologic diagnosis and histologic grade of appendicitis. Results Test performance of 57 identified candidate markers was studied in 67 patients, with median age of 11 years, 37% of whom had appendicitis. Several exhibited favorable diagnostic performance, including calgranulin A (S100-A8), α-1-acid glycoprotein 1 (orosomucoid), and leucine-rich α-2-glycoprotein (LRG), with the ROC AUC and values of 0.84 (95 % CI 0.72-0.95), 0.84 (0.72-0.95), and 0.97 (0.93-1.0), respectively. LRG was enriched in diseased appendices and its abundance correlated with severity of appendicitis. Conclusions High accuracy mass spectrometry urine proteome profiling allowed identification of diagnostic markers of acute appendicitis. Usage of LRG and other identified biomarkers may improve the diagnostic accuracy of clinical evaluations of appendicitis. PMID:19556024

  10. SpaceNav - A high accuracy navigation system for space applications

    Science.gov (United States)

    Evers, H.-H.

    The technology of the SpaceNav-system is based on research performed by the Institute of Flight Guidance and Control at the Technical University of Braunschweig, Germany. In 1989 this institute gave the worlds first public demonstration of a fully automatic landing of an aircraft, using inertial and satellite informations exclusively. The SpaceNav device components are: Acceleration-/Gyro Sensor Package; Global Positioning System (GPS) Receiver/optional more than one; Time Reference Unit; CPU; Telemetry (optional); and Differential GPS (DGPS) Receiver (optional). The coupling of GPS receivers with inertial sensors provides an extremely accurate navigation data set in real time applications even in phases with high dynamic conditions. The update rate of this navigation information is up to 100 Hz with the same accuracy in 3D-position, velocity, acceleration, attitude and time. SpaceNav is an integrated navigation system, which operates according to the principle of combining the longterm stability and accuracy of GPS, and the high level of dynamic precision of conventional inertial navigation system (INS) strapdown systems. The system's design allows other aiding sensors e.g. GLONASS satellite navigation system, distance measuring equipment (DME), altimeter (radar and/or barometric), flux valve etc. to be connected, in order to increase the redundancy of the system. The advantage of such an upgraded system is the availability of more sensor information than necessary for a navigation solution. The resulting redundancy in range measurement allows real-time detection and identification of sensor signals that are incompatible with the other information. As a result you get Receiver Autonomous Integrity Monitoring (RAIM) as described in 'A Multi-Sensor Approach to Assuring GPS Integrity', presented by Alison Brown in the March/April 1990 issue of 'GPS World'. In this paper the author presents information about the principles of the Satellite Navigation System GPS, and

  11. High accuracy of family history of melanoma in Danish melanoma cases

    DEFF Research Database (Denmark)

    Wadt, Karin A W; Drzewiecki, Krzysztof T; Gerdes, Anne-Marie

    2015-01-01

    The incidence of melanoma in Denmark has immensely increased over the last 10 years making Denmark a high risk country for melanoma. In the last two decades multiple public campaigns have sought to increase the awareness of melanoma. Family history of melanoma is a known major risk factor...... but previous studies have shown that self-reported family history of melanoma is highly inaccurate. These studies are 15 years old and we wanted to examine if a higher awareness of melanoma has increased the accuracy of self-reported family history of melanoma. We examined the family history of 181 melanoma...... probands who reported 199 cases of melanoma in relatives, of which 135 cases where in first degree relatives. We confirmed the diagnosis of melanoma in 77% of all relatives, and in 83% of first degree relatives. In 181 probands we validated the negative family history of melanoma in 748 first degree...

  12. High Accuracy mass Measurement of the very Short-Lived Halo Nuclide $^{11}$Li

    CERN Multimedia

    Le scornet, G

    2002-01-01

    The archetypal halo nuclide $^{11}$Li has now attracted a wealth of experimental and theoretical attention. The most outstanding property of this nuclide, its extended radius that makes it as big as $^{48}$Ca, is highly dependent on the binding energy of the two neutrons forming the halo. New generation experiments using radioactive beams with elastic proton scattering, knock-out and transfer reactions, together with $\\textit{ab initio}$ calculations require the tightening of the constraint on the binding energy. Good metrology also requires confirmation of the sole existing precision result to guard against a possible systematic deviation (or mistake). We propose a high accuracy mass determintation of $^{11}$Li, a particularly challenging task due to its very short half-life of 8.6 ms, but one perfectly suiting the MISTRAL spectrometer, now commissioned at ISOLDE. We request 15 shifts of beam time.

  13. Arithmetic Accuracy in Children From High- and Low-Income Schools

    Directory of Open Access Journals (Sweden)

    Elida V. Laski

    2016-04-01

    Full Text Available This study investigated income group differences in kindergartners’ and first graders’ (N = 161 arithmetic by examining the link between accuracy and strategy use on simple and complex addition problems. Low-income children were substantially less accurate than high-income children, in terms of both percentage of correctly solved problems and the magnitude of errors, with low-income first graders being less accurate than high-income kindergartners. Higher-income children were more likely to use sophisticated mental strategies than their lower-income peers, who used predominantly inefficient counting or inappropriate strategies. Importantly, this difference in strategies mediated the relation between income group and addition. Examining underlying strategies has implications for understanding income group differences in arithmetic and potential means of remedying it via instruction.

  14. High Accuracy Liquid Propellant Slosh Predictions Using an Integrated CFD and Controls Analysis Interface

    Science.gov (United States)

    Marsell, Brandon; Griffin, David; Schallhorn, Dr. Paul; Roth, Jacob

    2012-01-01

    Coupling computational fluid dynamics (CFD) with a controls analysis tool elegantly allows for high accuracy predictions of the interaction between sloshing liquid propellants and th e control system of a launch vehicle. Instead of relying on mechanical analogs which are not valid during aU stages of flight, this method allows for a direct link between the vehicle dynamic environments calculated by the solver in the controls analysis tool to the fluid flow equations solved by the CFD code. This paper describes such a coupling methodology, presents the results of a series of test cases, and compares said results against equivalent results from extensively validated tools. The coupling methodology, described herein, has proven to be highly accurate in a variety of different cases.

  15. Integrated CFD and Controls Analysis Interface for High Accuracy Liquid Propellant Slosh Predictions

    Science.gov (United States)

    Marsell, Brandon; Griffin, David; Schallhorn, Paul; Roth, Jacob

    2012-01-01

    Coupling computational fluid dynamics (CFD) with a controls analysis tool elegantly allows for high accuracy predictions of the interaction between sloshing liquid propellants and the control system of a launch vehicle. Instead of relying on mechanical analogs which are n0t va lid during all stages of flight, this method allows for a direct link between the vehicle dynamic environments calculated by the solver in the controls analysis tool to the fluid now equations solved by the CFD code. This paper describes such a coupling methodology, presents the results of a series of test cases, and compares said results against equivalent results from extensively validated tools. The coupling methodology, described herein, has proven to be highly accurate in a variety of different cases.

  16. Using Mobile Laser Scanning Data for Features Extraction of High Accuracy Driving Maps

    Science.gov (United States)

    Yang, Bisheng; Liu, Yuan; Liang, Fuxun; Dong, Zhen

    2016-06-01

    High Accuracy Driving Maps (HADMs) are the core component of Intelligent Drive Assistant Systems (IDAS), which can effectively reduce the traffic accidents due to human error and provide more comfortable driving experiences. Vehicle-based mobile laser scanning (MLS) systems provide an efficient solution to rapidly capture three-dimensional (3D) point clouds of road environments with high flexibility and precision. This paper proposes a novel method to extract road features (e.g., road surfaces, road boundaries, road markings, buildings, guardrails, street lamps, traffic signs, roadside-trees, power lines, vehicles and so on) for HADMs in highway environment. Quantitative evaluations show that the proposed algorithm attains an average precision and recall in terms of 90.6% and 91.2% in extracting road features. Results demonstrate the efficiencies and feasibilities of the proposed method for extraction of road features for HADMs.

  17. Initial development of high-accuracy CFRP panel for DATE5 antenna

    Science.gov (United States)

    Qian, Yuan; Lou, Zheng; Hao, Xufeng; Zhu, Jing; Cheng, Jingquan; Wang, Hairen; Zuo, Yingxi; Yang, Ji

    2016-07-01

    DATE5 antenna, which is a 5m telescope for terahertz exploration, will be sited at Dome A, Antarctica. It is necessary to keep high surface accuracy of the primary reflector panels so that high observing efficiency can be achieved. In antenna field, carbon fiber reinforced composite (CFRP) sandwich panels are widely used as these panels are light in weight, high in strength, low in thermal expansion, and cheap in mass fabrication. In DATE5 project, CFRP panels are important panel candidates. In the design study phase, a CFRP prototype panel of 1-meter size is initially developed for the verification purpose. This paper introduces the material arrangement in the sandwich panel, measured performance of this testing sandwich structure samples, and together with the panel forming process. For anti-icing in the South Pole region, a special CFRP heating film is embedded in the front skin of sandwich panel. The properties of some types of basic building materials are tested. Base on the results, the deformation of prototype panel with different sandwich structures and skin layers are simulated and a best structural concept is selected. The panel mold used is a high accuracy one with a surface rms error of 1.4 μm. Prototype panels are replicated from the mold. Room temperature curing resin is used to reduce the thermal deformation in the resin transfer process. In the curing, vacuum negative pressure technology is also used to increase the volume content of carbon fiber. After the measurement of the three coordinate measure machine (CMM), a prototype CFRP panel of 5.1 μm rms surface error is developed initially.

  18. Usability and accuracy of high-resolution detectors for daily quality assurance for robotic radiosurgery

    Directory of Open Access Journals (Sweden)

    Loutfi-Krauss Britta

    2017-09-01

    Full Text Available For daily CyberKnife QA a Winston-Lutz-Test (Automated-Quality-Assurance, AQA is used to determine sub-millimeter deviations in beam delivery accuracy. This test is performed using gafchromic film, an extensive and user-dependent method requiring the use of disposables. We therefore analyzed the usability and accuracy of high-resolution detector arrays. We analyzed a liquid-filled ionization-chamber array (Octavius 1000SRS, PTW, Germany, which has a central resolution of 2.5mm. To test sufficient sensitivity, beam profiles with robot shifts of 0.1mm along the arrays' axes were measured. The detected deviation between the shifted and central profile were compared to the real robot's position. We then compared the results to the SRS-Profiler (SunNuclear, USA with 4.0mm resolution and to the Nonius (QUART, Germany, a single-line diode detector with 2.8mm resolution. Finally, AQA variance and usability were analyzed performing a number of AQA tests over time, which required the use of specially designed fixtures for each array, and the results were compared to film. Concerning sensitivity, the 1000SRS detected the beam profile shifts with a maximum difference of 0.11mm (mean deviation = 0.03mm compared to the actual robot shift. The Nonius and SRS-Profiler showed differences of up to 0.15mm and 0.69mm with mean deviation of 0.05mm and 0.18mm, respectively. Analyzing the variation of AQA results over time, the 1000SRS showed a comparable standard deviation to film (0.26mm vs. 0.18mm. The SRS-Profiler and the Nonius showed a standard deviation of 0.16mm and 0.24mm, respectively. The 1000SRS seems to provide equivalent accuracy and sensitivity to the gold standard film when performing daily AQA tests. Compared to other detectors in our study the sensitivity as well as the accuracy of the 1000SRS appears to be superior and more user-friendly. Furthermore, no significant modification of the standard AQA procedure is required when introducing 1000SRS for

  19. PACMAN Project: A New Solution for the High-accuracy Alignment of Accelerator Components

    CERN Document Server

    Mainaud Durand, Helene; Buzio, Marco; Caiazza, Domenico; Catalán Lasheras, Nuria; Cherif, Ahmed; Doytchinov, Iordan; Fuchs, Jean-Frederic; Gaddi, Andrea; Galindo Munoz, Natalia; Gayde, Jean-Christophe; Kamugasa, Solomon; Modena, Michele; Novotny, Peter; Russenschuck, Stephan; Sanz, Claude; Severino, Giordana; Tshilumba, David; Vlachakis, Vasileios; Wendt, Manfred; Zorzetti, Silvia

    2016-01-01

    The beam alignment requirements for the next generation of lepton colliders have become increasingly challenging. As an example, the alignment requirements for the three major collider components of the CLIC linear collider are as follows. Before the first beam circulates, the Beam Position Monitors (BPM), Accelerating Structures (AS)and quadrupoles will have to be aligned up to 10 μm w.r.t. a straight line over 200 m long segments, along the 20 km of linacs. PACMAN is a study on Particle Accelerator Components' Metrology and Alignment to the Nanometre scale. It is an Innovative Doctoral Program, funded by the EU and hosted by CERN, providing high quality training to 10 Early Stage Researchers working towards a PhD thesis. The technical aim of the project is to improve the alignment accuracy of the CLIC components by developing new methods and tools addressing several steps of alignment simultaneously, to gain time and accuracy. The tools and methods developed will be validated on a test bench. This paper pr...

  20. An output amplitude configurable wideband automatic gain control with high gain step accuracy

    Institute of Scientific and Technical Information of China (English)

    何晓丰; 莫太山; 马成炎; 叶甜春

    2012-01-01

    An output amplitude configurable wideband automatic gain control (AGC) with high gain step accuracy for the GNSS receiver is presented.The amplitude of an AGC is configurable in order to cooperate with baseband chips to achieve interference suppression and be compatible with different full range ADCs.And what's more,the gain-boosting technology is introduced and the circuit is improved to increase the step accuracy.A zero,which is composed by the source feedback resistance and the source capacity,is introduced to compensate for the pole.The AGC is fabricated in a 0.18 μm CMOS process.The AGC shows a 62 dB gain control range by 1 dB each step with a gain error of less than 0.2 dB.The AGC provides 3 dB bandwidth larger than 80 MHz and the overall power consumption is less than 1.8 mA,and the die area is 800 × 300μm2.

  1. Accuracy of the high-throughput amplicon sequencing to identify species within the genus Aspergillus.

    Science.gov (United States)

    Lee, Seungeun; Yamamoto, Naomichi

    2015-12-01

    This study characterized the accuracy of high-throughput amplicon sequencing to identify species within the genus Aspergillus. To this end, we sequenced the internal transcribed spacer 1 (ITS1), β-tubulin (BenA), and calmodulin (CaM) gene encoding sequences as DNA markers from eight reference Aspergillus strains with known identities using 300-bp sequencing on the Illumina MiSeq platform, and compared them with the BLASTn outputs. The identifications with the sequences longer than 250 bp were accurate at the section rank, with some ambiguities observed at the species rank due to mostly cross detection of sibling species. Additionally, in silico analysis was performed to predict the identification accuracy for all species in the genus Aspergillus, where 107, 210, and 187 species were predicted to be identifiable down to the species rank based on ITS1, BenA, and CaM, respectively. Finally, air filter samples were analysed to quantify the relative abundances of Aspergillus species in outdoor air. The results were reproducible across biological duplicates both at the species and section ranks, but not strongly correlated between ITS1 and BenA, suggesting the Aspergillus detection can be taxonomically biased depending on the selection of the DNA markers and/or primers.

  2. Real-Time and High-Accuracy Arctangent Computation Using CORDIC and Fast Magnitude Estimation

    Directory of Open Access Journals (Sweden)

    Luca Pilato

    2017-03-01

    Full Text Available This paper presents an improved VLSI (Very Large Scale of Integration architecture for real-time and high-accuracy computation of trigonometric functions with fixed-point arithmetic, particularly arctangent using CORDIC (Coordinate Rotation Digital Computer and fast magnitude estimation. The standard CORDIC implementation suffers of a loss of accuracy when the magnitude of the input vector becomes small. Using a fast magnitude estimator before running the standard algorithm, a pre-processing magnification is implemented, shifting the input coordinates by a proper factor. The entire architecture does not use a multiplier, it uses only shift and add primitives as the original CORDIC, and it does not change the data path precision of the CORDIC core. A bit-true case study is presented showing a reduction of the maximum phase error from 414 LSB (angle error of 0.6355 rad to 4 LSB (angle error of 0.0061 rad, with small overheads of complexity and speed. Implementation of the new architecture in 0.18 µm CMOS technology allows for real-time and low-power processing of CORDIC and arctangent, which are key functions in many embedded DSP systems. The proposed macrocell has been verified by integration in a system-on-chip, called SENSASIP (Sensor Application Specific Instruction-set Processor, for position sensor signal processing in automotive measurement applications.

  3. High Accuracy Mass Measurement of the Dripline Nuclides $^{12,14}$Be

    CERN Multimedia

    2002-01-01

    State-of-the art, three-body nuclear models that describe halo nuclides require the binding energy of the halo neutron(s) as a critical input parameter. In the case of $^{14}$Be, the uncertainty of this quantity is currently far too large (130 keV), inhibiting efforts at detailed theoretical description. A high accuracy, direct mass deterlnination of $^{14}$Be (as well as $^{12}$Be to obtain the two-neutron separation energy) is therefore required. The measurement can be performed with the MISTRAL spectrometer, which is presently the only possible solution due to required accuracy (10 keV) and short half-life (4.5 ms). Having achieved a 5 keV uncertainty for the mass of $^{11}$Li (8.6 ms), MISTRAL has proved the feasibility of such measurements. Since the current ISOLDE production rate of $^{14}$Be is only about 10/s, the installation of a beam cooler is underway in order to improve MISTRAL transmission. The projected improvement of an order of magnitude (in each transverse direction) will make this measureme...

  4. Combined Scintigraphy and Tumor Marker Analysis Predicts Unfavorable Histopathology of Neuroblastic Tumors with High Accuracy.

    Directory of Open Access Journals (Sweden)

    Wolfgang Peter Fendler

    Full Text Available Our aim was to improve the prediction of unfavorable histopathology (UH in neuroblastic tumors through combined imaging and biochemical parameters.123I-MIBG SPECT and MRI was performed before surgical resection or biopsy in 47 consecutive pediatric patients with neuroblastic tumor. Semi-quantitative tumor-to-liver count-rate ratio (TLCRR, MRI tumor size and margins, urine catecholamine and NSE blood levels of neuron specific enolase (NSE were recorded. Accuracy of single and combined variables for prediction of UH was tested by ROC analysis with Bonferroni correction.34 of 47 patients had UH based on the International Neuroblastoma Pathology Classification (INPC. TLCRR and serum NSE both predicted UH with moderate accuracy. Optimal cut-off for TLCRR was 2.0, resulting in 68% sensitivity and 100% specificity (AUC-ROC 0.86, p < 0.001. Optimal cut-off for NSE was 25.8 ng/ml, resulting in 74% sensitivity and 85% specificity (AUC-ROC 0.81, p = 0.001. Combination of TLCRR/NSE criteria reduced false negative findings from 11/9 to only five, with improved sensitivity and specificity of 85% (AUC-ROC 0.85, p < 0.001.Strong 123I-MIBG uptake and high serum level of NSE were each predictive of UH. Combined analysis of both parameters improved the prediction of UH in patients with neuroblastic tumor. MRI parameters and urine catecholamine levels did not predict UH.

  5. High-accuracy same-beam VLBI observations using Shanghai and Urumqi telescopes

    Institute of Scientific and Technical Information of China (English)

    KIKUCHI; Fuyuhiko; KAMATA; Shun’ichi; MATSUMOTO; Koji; HANADA; Hideo

    2009-01-01

    The same-beam VLBI observations of Rstar and Vstar,which were two small satellites of Japanese lunar mission,SELENE,were successfully performed by using Shanghai and Urumqi 25-m telescopes. When the separation angle between Rstar and Vstar was less than 0.1 deg,the differential phase delay of the X-band signals between Rstar and Vstar on Shanghai-Urumqi baseline was obtained with a very small error of 0.15 mm rms,which was reduced by 1-2 order compared with the former VLBI results. When the separation angle was less than 0.56 deg,the differential phase delay of the S-band signals was also obtained with a very small error of several mm rms. The orbit determination for Rstar and Vstar was performed,and the accuracy was improved to a level of several meters by using VLBI and Doppler data. The high-accuracy same-beam differential VLBI technique is very useful in orbit determination for a spacecraft,and will be used in orbit determination for Mars missions of China Yinghuo-1 and Russia Phobos-grunt.

  6. High-accuracy same-beam VLBI observations using Shanghai and Urumqi telescopes

    Institute of Scientific and Technical Information of China (English)

    LIU QingHui; PING JingSong; FAN QingYuan; XIA Bo; AN Tao; QIAN ZhiHan; YANG WenJun; ZHANG Hua; WANG Zhen; WANG Na; SHI Xian; KIKUCHI Fuyuhiko; HUANG Qian; KAMATA Shun'ichi; MATSUMOTO Koji; HANADA Hideo; HONG XiaoYu; YU AiLi

    2009-01-01

    The same-beam VLBI observations of Rstar and Vstar, which were two small satellites of Japanese lunar mission, SELENE, were successfully performed by using Shanghai and Urumqi 25-m telescopes.When the separation angle between Rstar and Vstar was less than 0.1 deg, the differential phase delay of the X-band signals between Rstar and Vstar on Shanghai-Urumqi baseline was obtained with a very small error of 0.15 mm rms, which was reduced by 1-2 order compared with the former VLBI results.When the separation angle was less than 0.56 deg, the differential phase delay of the S-band signals was also obtained with a very small error of several mm rms. The orbit determination for Rstar and Vstar was performed, and the accuracy was improved to a level of several meters by using VLBI and Doppler data. The high-accuracy same-beam differential VLBI technique is very useful in orbit determination for a spacecraft, and will be used in orbit determination for Mars missions of China Yinghuo-1 and Russia Phobos-grunt.

  7. Reducing Systematic Centroid Errors Induced by Fiber Optic Faceplates in Intensified High-Accuracy Star Trackers

    Science.gov (United States)

    Xiong, Kun; Jiang, Jie

    2015-01-01

    Compared with traditional star trackers, intensified high-accuracy star trackers equipped with an image intensifier exhibit overwhelmingly superior dynamic performance. However, the multiple-fiber-optic faceplate structure in the image intensifier complicates the optoelectronic detecting system of star trackers and may cause considerable systematic centroid errors and poor attitude accuracy. All the sources of systematic centroid errors related to fiber optic faceplates (FOFPs) throughout the detection process of the optoelectronic system were analyzed. Based on the general expression of the systematic centroid error deduced in the frequency domain and the FOFP modulation transfer function, an accurate expression that described the systematic centroid error of FOFPs was obtained. Furthermore, reduction of the systematic error between the optical lens and the input FOFP of the intensifier, the one among multiple FOFPs and the one between the output FOFP of the intensifier and the imaging chip of the detecting system were discussed. Two important parametric constraints were acquired from the analysis. The correctness of the analysis on the optoelectronic detecting system was demonstrated through simulation and experiment. PMID:26016920

  8. Swing arm profilometer: high accuracy testing for large reaction-bonded silicon carbide optics with a capacitive probe

    Science.gov (United States)

    Xiong, Ling; Luo, Xiao; Hu, Hai-xiang; Zhang, Zhi-yu; Zhang, Feng; Zheng, Li-gong; Zhang, Xue-jun

    2017-08-01

    A feasible way to improve the manufacturing efficiency of large reaction-bonded silicon carbide optics is to increase the processing accuracy in the ground stage before polishing, which requires high accuracy metrology. A swing arm profilometer (SAP) has been used to measure large optics during the ground stage. A method has been developed for improving the measurement accuracy of SAP using a capacitive probe and implementing calibrations. The experimental result compared with the interferometer test shows the accuracy of 0.068 μm in root-mean-square (RMS) and maps in 37 low-order Zernike terms show accuracy of 0.048 μm RMS, which shows a powerful capability to provide a major input in high-precision grinding.

  9. [Diagnostic accuracy of the immersion high-frequency B-scan ultrasonography in chemical injured eyes].

    Science.gov (United States)

    Yang, Qinghua; Chen, Bing; Wang, Liqiang; Li, Zhaohui; Huang, Yifei

    2014-08-01

    To investigate the diagnostic accuracy of the immersion high-frequency B-scan ultrasonography, a noninvasive preoperative diagnosis method, in observing the anterior segment in chemical injured eyes. It was a retrospective study. Sixty-three ocular chemical injury patients (63 eyes), who accepted the keratoplasty or the artificial cornea transplant in PLA General Hospital from May 2011 to May 2013, were included in this study. All the injured eyes were examined by ultrasound bio-microscopy (UBM) and immersion high-frequency B-scan ultrasonography, respectively. The images were analyzed and the results were compared with the intraoperative findings. The observation of lens was the main parameter. All the 63 patients were examined with the UBM and the immersion high-frequency B-scan ultrasonography before the surgery. The findings of the cornea, anterior chamber angle, iris from UBM were consistent with those from the immersion high-frequency B-scan ultrasonography. As for the lens observation, in 32 eyes in which the lens were not detected by UBM, the lens were not detected in only 16 eyes, while 3 eyes with normal lens and 13 eyes with lens pacifications (1 eye with pyknotic lens) by immersion high-frequency B-scan ultrasonography. In 17 eyes in which the lens were found normal by UBM, there were only 14 eyes with normal lens and the rest 3 eyes' lens were found intumescent by immersion high-frequency B-scan ultrasonography. In 6 eyes in which lens were detected with suspicious by UBM, 2 eyes' lens were pyknotic and 4 eyes' lens were intumescent or clouded by immersion high-frequency B-scan ultrasonography. The findings of immersion high-frequency B-scan ultrasonography were highly consistent with the intraoperative findings. The lens could be observed accurately by immersion high-frequency B-scan ultrasonography in chemical injured eyes.

  10. High-accuracy infra-red thermography method using reflective marker arrays

    Science.gov (United States)

    Kirollos, Benjamin; Povey, Thomas

    2017-09-01

    In this paper, we describe a new method for high-accuracy infra-red (IR) thermography measurements in situations with significant spatial variation in reflected radiation from the surroundings, or significant spatial variation in surface emissivity due to viewing angle non-uniformity across the field of view. The method employs a reflective marker array (RMA) on the target surface—typically, high emissivity circular dots—and an integrated image analysis algorithm designed to require minimal human input. The new technique has two particular advantages which make it suited to high-accuracy measurements in demanding environments: (i) it allows the reflected radiation component to be calculated directly, in situ, and as a function of position, overcoming a key problem in measurement environments with non-uniform and unsteady stray radiation from the surroundings; (ii) using image analysis of the marker array (via apparent aspect ratio of the circular reflective markers), the local viewing angle of the target surface can be estimated, allowing corrections for angular variation of local emissivity to be performed without prior knowledge of the geometry. A third advantage of the technique is that allows for simple focus-stacking algorithms due to increased image entropy. The reflective marker array method is demonstrated for an isothermal, hemispherical object exposed to an external IR source arranged to give a significant non-uniform reflected radiation term. This is an example of a challenging environment, both because of the significant non-uniform reflected radiation term, and also the significant variation in target emissivity due to surface angle variation. We demonstrate that the new RMA IR technique leads to significantly lower error in evaluated surface temperature than conventional IR techniques. The method is applicable to any complex radiative environment.

  11. Design and calibration of a high-sensitivity and high-accuracy polarimeter based on liquid crystal variable retarders

    Science.gov (United States)

    Guo, Jing; Ren, De-Qing; Liu, Cheng-Chao; Zhu, Yong-Tian; Dou, Jiang-Pei; Zhang, Xi; Beck, Christian

    2017-01-01

    Polarimetry plays an important role in the measurement of solar magnetic fields. We developed a high-sensitivity and high-accuracy polarimeter (HHP) based on nematic liquid crystal variable retarders (LCVRs), which has a compact setup and no mechanical moving parts. The system design and calibration methods are discussed in detail. The azimuth error of the transmission axis of the polarizer as well as the fast axes of the two LCVRs and the quarter-wave plate were determined using dedicated procedures. Linearly and circularly polarized light were employed to evaluate the performance of the HHP. The experimental results indicate that a polarimetric sensitivity of better than \\[5.7 × {10 - 3}\\] can be achieved by using a single short-exposure image, while an accuracy on the order of 10‑5 can be reached by using a large number of short-exposure images. This makes the HHP a high-performance system that can be used with a ground-based solar telescope for high-precision solar magnetic field investigations.

  12. High accuracy Primary Reference gas Mixtures for high-impact greenhouse gases

    Science.gov (United States)

    Nieuwenkamp, Gerard; Zalewska, Ewelina; Pearce-Hill, Ruth; Brewer, Paul; Resner, Kate; Mace, Tatiana; Tarhan, Tanil; Zellweger, Christophe; Mohn, Joachim

    2017-04-01

    Climate change, due to increased man-made emissions of greenhouse gases, poses one of the greatest risks to society worldwide. High-impact greenhouse gases (CO2, CH4 and N2O) and indirect drivers for global warming (e.g. CO) are measured by the global monitoring stations for greenhouse gases, operated and organized by the World Meteorological Organization (WMO). Reference gases for the calibration of analyzers have to meet very challenging low level of measurement uncertainty to comply with the Data Quality Objectives (DQOs) set by the WMO. Within the framework of the European Metrology Research Programme (EMRP), a project to improve the metrology for high-impact greenhouse gases was granted (HIGHGAS, June 2014-May 2017). As a result of the HIGHGAS project, primary reference gas mixtures in cylinders for ambient levels of CO2, CH4, N2O and CO in air have been prepared with unprecedented low uncertainties, typically 3-10 times lower than usually previously achieved by the NMIs. To accomplish these low uncertainties in the reference standards, a number of preparation and analysis steps have been studied and improved. The purity analysis of the parent gases had to be performed with lower detection limits than previously achievable. E.g., to achieve an uncertainty of 2•10-9 mol/mol (absolute) on the amount fraction for N2O, the detection limit for the N2O analysis in the parent gases has to be in the sub nmol/mol domain. Results of an OPO-CRDS analyzer set-up in the 5µm wavelength domain, with a 200•10-12 mol/mol detection limit for N2O, will be presented. The adsorption effects of greenhouse gas components at cylinder surfaces are critical, and have been studied for different cylinder passivation techniques. Results of a two-year stability study will be presented. The fit-for-purpose of the reference materials was studied for possible variation on isotopic composition between the reference material and the sample. Measurement results for a suit of CO2 in air

  13. Very Low Power, Low Voltage, High Accuracy, and High Performance Current Mirror

    Institute of Scientific and Technical Information of China (English)

    Hassan Faraji Baghtash; Khalil Monfaredi; Ahmad Ayatollahi

    2011-01-01

    A novel low power and low voltage current mirror with a very low current copy error is presented and the principle of its operation is discussed.In this circuit,the gain boosting regulated cascode scheme is used to improve the output resistance,while using inverter as an amplifier.The simulation results with HSPICE in TSMC 0.18 μm CMOS technology are given,which verify the high performance of the proposed structure.Simulation results show an input resistance of 0.014 Ω and an output resistance of 3 GΩ.The current copy error is favorable as low as 0.002% together with an input (the minimum input voltage of vin,min~ 0.24 V) and an output (the minimum output voltage of vout,min~ 0.16 V) compliances while working with the 1 V power supply and the 50 μA input current.The current copy error is near zero at the input current of 27 μA.It consumes only 76 μW and introduces a very low output offset current of 50 pA.

  14. ADFE METHOD WITH HIGH ACCURACY FOR NONLINEAR PARABOLIC INTEGRO-DIFFERENTIAL SYSTEM WITH NONLINEAR BOUNDARY CONDITIONS

    Institute of Scientific and Technical Information of China (English)

    崔霞

    2002-01-01

    Alternating direction finite element (ADFE) scheme for d-dimensional nonlinear system of parabolic integro-differential equations is studied. By using a local approximation based on patches of finite elements to treat the capacity term qi(u), decomposition of the coefficient matrix is realized; by using alternating direction, the multi-dimensional problem is reduced to a family of single space variable problems, calculation work is simplified; by using finite element method, high accuracy for space variant is kept; by using inductive hypothesis reasoning, the difficulty coming from the nonlinearity of the coefficients and boundary conditions is treated; by introducing Ritz-Volterra projection, the difficulty coming from the memory term is solved. Finally, by using various techniques for priori estimate for differential equations, the unique resolvability and convergence properties for both FE and ADFE schemes are rigorously demonstrated, and optimal H1 and L2norm space estimates and O((△t)2) estimate for time variant are obtained.

  15. SLSTR: a high accuracy dual scan temperature radiometer for sea and land surface monitoring from space

    Science.gov (United States)

    Coppo, P.; Ricciarelli, B.; Brandani, F.; Delderfield, J.; Ferlet, M.; Mutlow, C.; Munro, G.; Nightingale, T.; Smith, D.; Bianchi, S.; Nicol, P.; Kirschstein, S.; Hennig, T.; Engel, W.; Frerick, J.; Nieke, J.

    2010-10-01

    SLSTR is a high accuracy infrared radiometer which will be embarked in the Earth low-orbit Sentinel 3 operational GMES mission. SLSTR is an improved version of the previous AATSR and ATSR-1/2 instruments which have flown respectively on Envisat and ERS-1/2 ESA missions. SLSTR will provide data continuity with respect to these previous missions but with a substantial improvement due to its higher swaths (750 km in dual view and 1400 km in single view) which should permit global coverage of SST and LST measurements (at 1 km of spatial resolution in IR channels) with daily revisit time, useful for climatological and meteorological applications. Two more SWIR channels and a higher spatial resolution in the VIS/SWIR channels (0.5 km) are also implemented for a better clouds/aerosols screening. Two further additional channels for global scale fire monitoring are present at the same time as the other nominal channels.

  16. Study on Calibration System for Electronic Transformers Based on High-Accuracy PCI Card

    Directory of Open Access Journals (Sweden)

    Mingzhu Zhang

    2013-03-01

    Full Text Available With preliminary applying of Electronic Transformer (ET based on IEC 61850 standards in power grid, the calibrations of tested transformers have attracted extensive research attention. This study proposes a novel Calibration System of ET (CSET based on high-accuracy card. Data acquisition of ET and Standard Trans-former (ST is gotten by optic Ethernet and PCI-4462 data acquisition card, respectively. Meanwhile, the synchronized sampling between ET and ST is completed on the optic/electronic pulse signal of PCI synchronization card. The signals processing and human interface are realized by Labview software. The system proposed in the study is feasible for calibrating Electronic Voltage/Current Transformers (EVT/ECT of different voltage classes. System tests show that the precision of the system can get to 0.2°.

  17. Study on Calibration System for Electronic Transformers Based on High-Accuracy PCI Card

    Directory of Open Access Journals (Sweden)

    Mingzhu Zhang

    2013-05-01

    Full Text Available With preliminary applying of Electronic Transformer (ET based on IEC 61850 standards in power grid, the calibration of tested transformers has attracted extensive research attention. This study proposes a novel Calibration System of ET (CSET based on high-accuracy card. Data acquisition of ET and standard trans-former (ST is gotten by optic Ethernet and PCI-4462 data acquisition card, respectively. Meanwhile, the synchronized sampling between ET and ST is completed on the optic/electronic pulse signal of PCI synchronization card. The signals processing and human interface are realized by Lab view software. The system proposed in the study is feasible for calibrating Electronic Voltage/Current Transformers (EVT/ECT of different voltage classes. System tests show that the precision of the system can get to 0.2°.

  18. High-Accuracy Programmable Timing Generator with Wide-Range Tuning Capability

    Directory of Open Access Journals (Sweden)

    Ting-Li Chu

    2013-01-01

    Full Text Available In this paper, a high-accuracy programmable timing generator with wide-range tuning capability is proposed. With the aid of dual delay-locked loop (DLL, both of the coarse- and fine-tuning mechanisms are operated in precise closed-loop scheme to lessen the effects of the ambient variations. The timing generator can provide sub-gate resolution and instantaneous switching capability. The circuit is implemented and simulated in TSMC 0.18 μm 1P6M technology. The test chip area occupies 1.9 mm2. The reference clock cycle can be divided into 128 bins by interpolation to obtain 14 ps resolution with the clock rate at 550 MHz. The INL and DNL are within −0.21~+0.78 and −0.27~+0.43 LSB, respectively.

  19. Well-posedness of the difference schemes of the high order of accuracy for elliptic equations

    Directory of Open Access Journals (Sweden)

    2006-01-01

    Full Text Available It is well known the differential equation − u ″ ( t +Au( t =f( t ( −∞high order of accuracy two-step difference schemes generated by an exact difference scheme or by Taylor's decomposition on three points for the approximate solutions of this differential equation. The well-posedness of these difference schemes in the difference analogy of the smooth functions is obtained. The exact almost coercive inequality for solutions in C( τ,E of these difference schemes is established.

  20. High-accuracy measurement of the magnetic moment anomaly of the electron bound in hydrogenlike carbon.

    Science.gov (United States)

    Häffner, H; Beier, T; Hermanspahn, N; Kluge, H J; Quint, W; Stahl, S; Verdú, J; Werth, G

    2000-12-18

    We present a new experimental value for the magnetic moment of the electron bound in hydrogenlike carbon (12C5+): g(exp) = 2.001 041 596 (5). This is the most precise determination of an atomic g(J) factor so far. The experiment was carried out on a single 12C5+ ion stored in a Penning trap. The high accuracy was made possible by spatially separating the induction of spin flips and the analysis of the spin direction. The current theoretical value amounts to g(th) = 2.001 041 591 (7). Together experiment and theory test the bound-state QED contributions to the g(J) factor of a bound electron to a precision of 1%.

  1. Computer-aided diagnosis of breast MRI with high accuracy optical flow estimation

    Science.gov (United States)

    Meyer-Baese, Anke; Barbu, Adrian; Lobbes, Marc; Hoffmann, Sebastian; Burgeth, Bernhard; Kleefeld, Andreas; Meyer-Bäse, Uwe

    2015-05-01

    Non-mass enhancing lesions represent a challenge for the radiological reading. They are not well-defined in both morphology (geometric shape) and kinetics (temporal enhancement) and pose a problem to lesion detection and classification. To enhance the discriminative properties of an automated radiological workflow, the correct preprocessing steps need to be taken. In an usual computer-aided diagnosis (CAD) system, motion compensation plays an important role. To this end, we employ a new high accuracy optical flow based motion compensation algorithm with robustification variants. An automated computer-aided diagnosis system evaluates the atypical behavior of these lesions, and additionally considers the impact of non-rigid motion compensation on a correct diagnosis.

  2. High Accuracy Speed-fed Grating Angular Acceleration Measurement System Based on FPGA

    Directory of Open Access Journals (Sweden)

    Hao Zhao

    2012-09-01

    Full Text Available Shaft angular acceleration is one of the most important parameter of rotary machines, the error of angular acceleration increased when the shaft speed up. For this problem, a new high accuracy angular acceleration measurement system is presented, the principle of measurement is self-regulating the period of speed sampling signal according to the proportion of the shaft speed up. This measurement system combined FPGA and SCM, the speed of shaft is received by the timer of SCM responding the interrupts of FPGA, and then set the parameter of frequency divider in FPGA, so as to make the period of speed sampling consistent with the proportion of the speed up. This measurement system could overcome the error when system speed up according to the experiment.

  3. High Accuracy Reference Network (HARN), Published in 2000, 1:600 (1in=50ft) scale, Brown County, WI.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This High Accuracy Reference Network (HARN) dataset, published at 1:600 (1in=50ft) scale, was produced all or in part from Field Survey/GPS information as of 2000....

  4. 库岸公路岩石边坡极限破坏角研究%On the critical angle deformation of reservoir bank highway rock slopes

    Institute of Scientific and Technical Information of China (English)

    周志军

    2012-01-01

    为了准确评价库岸公路岩石边坡的稳定性,合理指导工程施工,保证开挖边坡安全,考虑发生连续降雨、洪水等引起库水位抬高后,库岸公路岩石边坡滑动面处于饱水状态时的滑动面渗水压力,建立了渗压效应下岩石边坡的滑动简化模型.然后进行边坡上力的分析推导,得出边坡的坡高、坡角和极限破坏角之间的关系式,并对关系式进行求解,得出库岸公路岩石边坡极限破坏角公式.最后利用该公式对安康至陕川界高速公路沿线典型边坡计算并进行回归分析,得出沿线边坡坡高和坡角之间的关系式和极限破坏角公式.计算结果与实际相符.%This paper takes its main interest in the study of the critical angle deformation of reservoir bank highway rock slopes. As is known, a lot of methods and models are used for the time being to assess the stability of such deformation,for example, the limit equilibrium method and catastrophe theory. Statistically speaking,over 90% of the rock slope failure involves groundwater penetration or permeating, which implies that water is a key factor affecting the slope stability . However, it is rare for the researchers of rock slope to pay enough attention to studying the seepage pressure of sliding surface on the slope stability. Seeing the above said factors, the author of this paper is willing to turn the our direction to and take into full account such factors, as the continuous rainfall, flood discharge and so on, which may cause upraise of water level in the reservoir, in better assessing the stability of reservoir banks highway rock slope along with giving proper directions to water-conservation and highway-building engineering projects. In doing so, first of all, we have established a simplified model of sliding slope in condition of infiltration pressure, when gliding deformation of such rock slopes in case of water-saturated. And, then, the correlation equation can be derived

  5. High-accuracy approximation of high-rank derivatives: isotropic finite differences based on lattice-Boltzmann stencils.

    Science.gov (United States)

    Mattila, Keijo Kalervo; Hegele Júnior, Luiz Adolfo; Philippi, Paulo Cesar

    2014-01-01

    We propose isotropic finite differences for high-accuracy approximation of high-rank derivatives. These finite differences are based on direct application of lattice-Boltzmann stencils. The presented finite-difference expressions are valid in any dimension, particularly in two and three dimensions, and any lattice-Boltzmann stencil isotropic enough can be utilized. A theoretical basis for the proposed utilization of lattice-Boltzmann stencils in the approximation of high-rank derivatives is established. In particular, the isotropy and accuracy properties of the proposed approximations are derived directly from this basis. Furthermore, in this formal development, we extend the theory of Hermite polynomial tensors in the case of discrete spaces and present expressions for the discrete inner products between monomials and Hermite polynomial tensors. In addition, we prove an equivalency between two approaches for constructing lattice-Boltzmann stencils. For the numerical verification of the presented finite differences, we introduce 5th-, 6th-, and 8th-order two-dimensional lattice-Boltzmann stencils.

  6. Study of high-altitude radar altimeter model accuracy and SITAN performance using HAAFT data

    Energy Technology Data Exchange (ETDEWEB)

    Shieves, T.C.; Callahan, M.W.

    1979-07-01

    Radar altimetry data, inertial navigation data, and scoring data were collected under the HAAFT program by Martin Marietta Corporation for the United States Air Force over several areas in the western United States at altitudes ranging from 3 to 20 km. The study reported here uses the HAAFT data in conjunction with Defense Mapping Agency (DMA) topographic data to evaluate the accuracy of a high-altitude pulsed-radar altimeter model and the resulting performance of the terrain-aided guidance concept SITAN. Previous SITAN flight tests at low altitudes (less than 1500 m AGL) have demonstrated 6-20 m CEP. The high-altitude flight test data analyzed herein show a SITAN CEP of 120 m. The radar altimeter model was required to achieve this performance includes the effects of the internal track loop, AGC loop, antenna beamwidth, and the terrain radar cross section and provided a factor of 6 improvement over simple nadir ground clearance for rough terrain. It is postulated that high-altitude CEP could be reduced to 50 m or less if an altimeter were designed specifically for high-altitude terrain sensing.

  7. TECHNOLOGICAL PROVISION OF ACCURACY AND QUALITY PARAMETERS OF INTRICATE PROFILE PARTS AT HIGH-SPEED MULTI-COORDINATE MACHINING

    Directory of Open Access Journals (Sweden)

    V. K. Sheleg

    2009-01-01

    Full Text Available The paper considers requirements to CAM-systems for provision of high-speed multi-coordinate milling, principles of generation and recommendations on trajectory programming for high-speed machining, influence of vibration and balancing of the technological system on parameters of  the machining accuracy, characteristics of a cutting tool, types of tool coatings that is rather actual for improvement of accuracy and quality of intricate profile parts.

  8. Integrative fitting of absorption line profiles with high accuracy, robustness, and speed

    Science.gov (United States)

    Skrotzki, Julian; Habig, Jan Christoph; Ebert, Volker

    2014-08-01

    The principle of the integrative evaluation of absorption line profiles relies on the numeric integration of absorption line signals to retrieve absorber concentrations, e.g., of trace gases. Thus, it is a fast and robust technique. However, previous implementations of the integrative evaluation principle showed shortcomings in terms of accuracy and the lack of a fit quality indicator. This has motivated the development of an advanced integrative (AI) fitting algorithm. The AI fitting algorithm retains the advantages of previous integrative implementations—robustness and speed—and is able to achieve high accuracy by introduction of a novel iterative fitting process. A comparison of the AI fitting algorithm with the widely used Levenberg-Marquardt (LM) fitting algorithm indicates that the AI algorithm has advantages in terms of robustness due to its independence from appropriately chosen start values for the initialization of the fitting process. In addition, the AI fitting algorithm shows speed advantages typically resulting in a factor of three to four shorter computational times on a standard personal computer. The LM algorithm on the other hand retains advantages in terms of a much higher flexibility, as the AI fitting algorithm is restricted to the evaluation of single absorption lines with precomputed line width. Comparing both fitting algorithms for the specific application of in situ laser hygrometry at 1,370 nm using direct tunable diode laser absorption spectroscopy (TDLAS) suggests that the accuracy of the AI algorithm is equivalent to that of the LM algorithm. For example, a signal-to-noise ratio of 80 and better typically yields a deviation of TDLAS hygrometry at the aerosol and cloud chamber aerosol interactions and dynamics in the atmosphere (AIDA)—a unique large-scale facility to study atmospheric processes. The robustness of the AI fitting algorithm has been validated for typical AIDA conditions encompassing strong transmission fluctuations

  9. Improved photomask accuracy with a high-productivity DUV laser pattern generator

    Science.gov (United States)

    Öström, Thomas; Måhlén, Jonas; Karawajczyk, Andrzej; Rosling, Mats; Carlqvist, Per; Askebjer, Per; Karlin, Tord; Sallander, Jesper; Österberg, Anders

    2006-10-01

    A strategy for sub-100 nm technology nodes is to maximize the use of high-speed deep-UV laser pattern generators, reserving e-beam tools for the most critical photomask layers. With a 248 nm excimer laser and 0.82 NA projection optics, the Sigma7500 increases the application space of laser pattern generators. A programmable spatial light modulator (SLM) is imaged with partially coherent optics to compose the photomask pattern. Image profiles are enhanced with phase shifting in the pattern generator, and features below 200 nm are reliably printed. The Sigma7500 extends the SLM-based architecture with improvements to CD uniformity and placement accuracy, resulting from an error budget-based methodology. Among these improvements is a stiffer focus stage design with digital servos, resulting in improved focus stability. Tighter climate controls and improved dose control reduce drift during mask patterning. As a result, global composite CD uniformity below 5 nm (3σ) has been demonstrated, with placement accuracy below 10 nm (3σ) across the mask. Self-calibration methods are used to optimize and monitor system performance, reducing the need to print test plates. The SLM calibration camera views programmed test patterns, making it possible to evaluate image metrics such as CD uniformity and line edge roughness. The camera is also used to characterize image placement over the optical field. A feature called ProcessEqualizer TM has been developed to correct long-range CD errors arising from process effects on production photomasks. Mask data is sized in real time to compensate for pattern-dependent errors related to local pattern density, as well as for systematic pattern-independent errors such as radial CD signatures. Corrections are made in the pixel domain in the advanced adjustments processor, which also performs global biasing, stamp distortion compensation, and corner enhancement. In the Sigma7500, the mask pattern is imaged with full edge addressability in each

  10. A new device for liver cancer biomarker detection with high accuracy

    Directory of Open Access Journals (Sweden)

    Shuaipeng Wang

    2015-06-01

    Full Text Available A novel cantilever array-based bio-sensor was batch-fabricated with IC compatible MEMS technology for precise liver cancer bio-marker detection. A micro-cavity was designed in the free end of the cantilever for local antibody-immobilization, thus adsorption of the cancer biomarker is localized in the micro-cavity, and the adsorption-induced k variation can be dramatically reduced with comparison to that caused by adsorption of the whole lever. The cantilever is pizeoelectrically driven into vibration which is pizeoresistively sensed by Wheatstone bridge. These structural features offer several advantages: high sensitivity, high throughput, high mass detection accuracy, and small volume. In addition, an analytical model has been established to eliminate the effect of adsorption-induced lever stiffness change and has been applied to precise mass detection of cancer biomarker AFP, the detected AFP antigen mass (7.6 pg/ml is quite close to the calculated one (5.5 pg/ml, two orders of magnitude better than the value by the fully antibody-immobilized cantilever sensor. These approaches will promote real application of the cantilever sensors in early diagnosis of cancer.

  11. High Accuracy Decoding of Dynamical Motion from a Large Retinal Population.

    Directory of Open Access Journals (Sweden)

    Olivier Marre

    2015-07-01

    Full Text Available Motion tracking is a challenge the visual system has to solve by reading out the retinal population. It is still unclear how the information from different neurons can be combined together to estimate the position of an object. Here we recorded a large population of ganglion cells in a dense patch of salamander and guinea pig retinas while displaying a bar moving diffusively. We show that the bar's position can be reconstructed from retinal activity with a precision in the hyperacuity regime using a linear decoder acting on 100+ cells. We then took advantage of this unprecedented precision to explore the spatial structure of the retina's population code. The classical view would have suggested that the firing rates of the cells form a moving hill of activity tracking the bar's position. Instead, we found that most ganglion cells in the salamander fired sparsely and idiosyncratically, so that their neural image did not track the bar. Furthermore, ganglion cell activity spanned an area much larger than predicted by their receptive fields, with cells coding for motion far in their surround. As a result, population redundancy was high, and we could find multiple, disjoint subsets of neurons that encoded the trajectory with high precision. This organization allows for diverse collections of ganglion cells to represent high-accuracy motion information in a form easily read out by downstream neural circuits.

  12. Model Accuracy Comparison for High Resolution Insar Coherence Statistics Over Urban Areas

    Science.gov (United States)

    Zhang, Yue; Fu, Kun; Sun, Xian; Xu, Guangluan; Wang, Hongqi

    2016-06-01

    The interferometric coherence map derived from the cross-correlation of two complex registered synthetic aperture radar (SAR) images is the reflection of imaged targets. In many applications, it can act as an independent information source, or give additional information complementary to the intensity image. Specially, the statistical properties of the coherence are of great importance in land cover classification, segmentation and change detection. However, compared to the amount of work on the statistical characters of SAR intensity, there are quite fewer researches on interferometric SAR (InSAR) coherence statistics. And to our knowledge, all of the existing work that focuses on InSAR coherence statistics, models the coherence with Gaussian distribution with no discrimination on data resolutions or scene types. But the properties of coherence may be different for different data resolutions and scene types. In this paper, we investigate on the coherence statistics for high resolution data over urban areas, by making a comparison of the accuracy of several typical statistical models. Four typical land classes including buildings, trees, shadow and roads are selected as the representatives of urban areas. Firstly, several regions are selected from the coherence map manually and labelled with their corresponding classes respectively. Then we try to model the statistics of the pixel coherence for each type of region, with different models including Gaussian, Rayleigh, Weibull, Beta and Nakagami. Finally, we evaluate the model accuracy for each type of region. The experiments on TanDEM-X data show that the Beta model has a better performance than other distributions.

  13. Prioritizing spatial accuracy in high-resolution fMRI data using multivariate feature weight mapping

    Directory of Open Access Journals (Sweden)

    Johannes eStelzer

    2014-04-01

    Full Text Available Although ultra-high-field fMRI at field strengths of 7T or above provides substantial gains in BOLD contrast-to-noise ratio, when very high-resolution fMRI is required such gains are inevitably reduced. The improvement in sensitivity provided by multivariate analysis techniques, as compared with univariate methods, then becomes especially welcome. Information mapping approaches are commonly used, such as the searchlight technique, which take into account the spatially distributed patterns of activation in order to predict stimulus conditions. However, the popular searchlight decoding technique, in particular, has been found to be prone to spatial inaccuracies. For instance, the spatial extent of informative areas is generally exaggerated, and their spatial configuration is distorted. We propose the combination of a nonparametric and permutation-based statistical framework with linear classifiers. We term this new combined method Feature Weight Mapping (FWM. The main goal of the proposed method is to map the specific contribution of each voxel to the classification decision while including a correction for the multiple comparisons problem. Next, we compare this new method to the searchlight approach using a simulation and ultra-high-field 7T experimental data. We found that the searchlight method led to spatial inaccuracies that are especially noticeable in high-resolution fMRI data. In contrast, FWM was more spatially precise, revealing both informative anatomical structures as well as the direction by which voxels contribute to the classification. By maximizing the spatial accuracy of ultra-high-field fMRI results, global multivariate methods provide a substantial improvement for characterizing structure-function relationships.

  14. High-resolution CT of nontuberculous mycobacterium infection in adult CF patients: diagnostic accuracy

    Energy Technology Data Exchange (ETDEWEB)

    McEvoy, Sinead; Lavelle, Lisa; Kilcoyne, Aoife; McCarthy, Colin; Dodd, Jonathan D. [St. Vincent' s University Hospital, Department of Radiology, Dublin (Ireland); DeJong, Pim A. [University Medical Center Utrecht, Department of Radiology, Utrecht (Netherlands); Loeve, Martine; Tiddens, Harm A.W.M. [Erasmus MC-Sophia Children' s Hospital, Department of Radiology, Department of Pediatric Pulmonology and Allergology, Rotterdam (Netherlands); McKone, Edward; Gallagher, Charles G. [St. Vincent' s University Hospital, Department of Respiratory Medicine and National Referral Centre for Adult Cystic Fibrosis, Dublin (Ireland)

    2012-12-15

    To determine the diagnostic accuracy of high-resolution computed tomography (HRCT) for the detection of nontuberculous mycobacterium infection (NTM) in adult cystic fibrosis (CF) patients. Twenty-seven CF patients with sputum-culture-proven NTM (NTM+) underwent HRCT. An age, gender and spirometrically matched group of 27 CF patients without NTM (NTM-) was included as controls. Images were randomly and blindly analysed by two readers in consensus and scored using a modified Bhalla scoring system. Significant differences were seen between NTM (+) and NTM (-) patients in the severity of the bronchiectasis subscore [45 % (1.8/4) vs. 35 % (1.4/4), P = 0.029], collapse/consolidation subscore [33 % (1.3/3) vs. 15 % (0.6/3)], tree-in-bud/centrilobular nodules subscore [43 % (1.7/3) vs. 25 % (1.0/3), P = 0.002] and the total CT score [56 % (18.4/33) vs. 46 % (15.2/33), P = 0.002]. Binary logistic regression revealed BMI, peribronchial thickening, collapse/consolidation and tree-in-bud/centrilobular nodules to be predictors of NTM status (R{sup 2} = 0.43). Receiver-operator curve analysis of the regression model showed an area under the curve of 0.89, P < 0.0001. In adults with CF, seven or more bronchopulmonary segments showing tree-in-bud/centrilobular nodules on HRCT is highly suggestive of NTM colonisation. (orig.)

  15. Rigorous Training of Dogs Leads to High Accuracy in Human Scent Matching-To-Sample Performance.

    Directory of Open Access Journals (Sweden)

    Sophie Marchal

    Full Text Available Human scent identification is based on a matching-to-sample task in which trained dogs are required to compare a scent sample collected from an object found at a crime scene to that of a suspect. Based on dogs' greater olfactory ability to detect and process odours, this method has been used in forensic investigations to identify the odour of a suspect at a crime scene. The excellent reliability and reproducibility of the method largely depend on rigor in dog training. The present study describes the various steps of training that lead to high sensitivity scores, with dogs matching samples with 90% efficiency when the complexity of the scents presented during the task in the sample is similar to that presented in the in lineups, and specificity reaching a ceiling, with no false alarms in human scent matching-to-sample tasks. This high level of accuracy ensures reliable results in judicial human scent identification tests. Also, our data should convince law enforcement authorities to use these results as official forensic evidence when dogs are trained appropriately.

  16. High accuracy jog CD control on OPC pattern by advanced laser writer Sigma7500

    Science.gov (United States)

    Chin, Tomas; Wu, Wen-Bin; Shih, Chiang-Lin

    2008-10-01

    With the progress of mask writer technology, 50 KV electron beam writers always perform with better pattern fidelity and critical dimension (CD) control than traditional laser raster-scan writers because laser spot size is confined by the laser longer wavelength relative to electron beam. As far as Optical Proximity Correction (OPC) pattern fidelity is concerned, critical masks with OPC process have to choose Variable-Shape-Beam (VSB) electron beam writer presently. However, the over-aggressive OPC fragmentation induces data volume abrupt explosion, longer writing time, higher mask cost and even mask quality degradation 1. Micronic Sigma7500 laser writer introduces a novel imaging system combining partial coherent light and DUV spatial light modulation (SLM) to generate a high-quality pattern image 2. The benefit of raster-scan laser writer is high throughput with consistent writing time regardless of pattern geometry, complexity and data size. However, pattern CD accuracy still needs improvement. This study is to evaluate jog CD control capability of Sigma7500 on OPC typical line-and-space test patterns with different orientations of 0°, 90°, 45° and 135°. In addition, mask CD uniformity and OPC jog height linearity will also be demonstrated.

  17. High-Accuracy Ring Laser Gyroscopes: Earth Rotation Rate and Relativistic Effects

    Science.gov (United States)

    Beverini, N.; Di Virgilio, A.; Belfi, J.; Ortolan, A.; Schreiber, K. U.; Gebauer, A.; Klügel, T.

    2016-06-01

    The Gross Ring G is a square ring laser gyroscope, built as a monolithic Zerodur structure with 4 m length on all sides. It has demonstrated that a large ring laser provides a sensitivity high enough to measure the rotational rate of the Earth with a high precision of ΔΩE GINGER project is intending to take this level of sensitivity further and to improve the accuracy and the long-term stability. A monolithic structure similar to the G ring laser is not available for GINGER. Therefore the preliminary goal is the demonstration of the feasibility of a larger gyroscope structure, where the mechanical stability is obtained through an active control of the geometry. A prototype moderate size gyroscope (GP-2) has been set up in Pisa in order to test this active control of the ring geometry, while a second structure (GINGERino) has been installed inside the Gran Sasso underground laboratory in order to investigate the properties of a deep underground laboratory in view of an installation of a future GINGER apparatus. The preliminary data on these two latter instruments are presented.

  18. High accuracy and transferability of a neural network potential through charge equilibration for calcium fluoride

    Science.gov (United States)

    Faraji, Somayeh; Ghasemi, S. Alireza; Rostami, Samare; Rasoulkhani, Robabe; Schaefer, Bastian; Goedecker, Stefan; Amsler, Maximilian

    2017-03-01

    We investigate the accuracy and transferability of a recently developed high-dimensional neural network (NN) method for calcium fluoride, fitted to a database of ab initio density functional theory (DFT) calculations based on the Perdew-Burke-Ernzerhof (PBE) exchange correlation functional. We call the method charge equilibration via neural network technique (CENT). Although the fitting database contains only clusters (i.e., nonperiodic structures), the NN scheme accurately describes a variety of bulk properties. In contrast to other available empirical methods the CENT potential has a much simpler functional form, nevertheless it correctly reproduces the PBE energetics of various crystalline phases both at ambient and high pressure. Surface energies and structures as well as dynamical properties derived from phonon calculations are also in good agreement with PBE results. Overall, the difference between the values obtained by the CENT potential and the PBE reference values is less than or equal to the difference between the values of local density approximation (LDA) and Born-Mayer-Huggins (BMH) with those calculated by the PBE exchange correlation functional.

  19. Spline-based high-accuracy piecewise-polynomial phase-to-sinusoid amplitude converters.

    Science.gov (United States)

    Petrinović, Davor; Brezović, Marko

    2011-04-01

    We propose a method for direct digital frequency synthesis (DDS) using a cubic spline piecewise-polynomial model for a phase-to-sinusoid amplitude converter (PSAC). This method offers maximum smoothness of the output signal. Closed-form expressions for the cubic polynomial coefficients are derived in the spectral domain and the performance analysis of the model is given in the time and frequency domains. We derive the closed-form performance bounds of such DDS using conventional metrics: rms and maximum absolute errors (MAE) and maximum spurious free dynamic range (SFDR) measured in the discrete time domain. The main advantages of the proposed PSAC are its simplicity, analytical tractability, and inherent numerical stability for high table resolutions. Detailed guidelines for a fixed-point implementation are given, based on the algebraic analysis of all quantization effects. The results are verified on 81 PSAC configurations with the output resolutions from 5 to 41 bits by using a bit-exact simulation. The VHDL implementation of a high-accuracy DDS based on the proposed PSAC with 28-bit input phase word and 32-bit output value achieves SFDR of its digital output signal between 180 and 207 dB, with a signal-to-noise ratio of 192 dB. Its implementation requires only one 18 kB block RAM and three 18-bit embedded multipliers in a typical field-programmable gate array (FPGA) device.

  20. High-Accuracy, Compact Scanning Method and Circuit for Resistive Sensor Arrays

    Directory of Open Access Journals (Sweden)

    Jong-Seok Kim

    2016-01-01

    Full Text Available The zero-potential scanning circuit is widely used as read-out circuit for resistive sensor arrays because it removes a well known problem: crosstalk current. The zero-potential scanning circuit can be divided into two groups based on type of row drivers. One type is a row driver using digital buffers. It can be easily implemented because of its simple structure, but we found that it can cause a large read-out error which originates from on-resistance of the digital buffers used in the row driver. The other type is a row driver composed of operational amplifiers. It, very accurately, reads the sensor resistance, but it uses a large number of operational amplifiers to drive rows of the sensor array; therefore, it severely increases the power consumption, cost, and system complexity. To resolve the inaccuracy or high complexity problems founded in those previous circuits, we propose a new row driver which uses only one operational amplifier to drive all rows of a sensor array with high accuracy. The measurement results with the proposed circuit to drive a 4 × 4 resistor array show that the maximum error is only 0.1% which is remarkably reduced from 30.7% of the previous counterpart.

  1. Assessing the Accuracy of Sentinel-3 SLSTR Sea-Surface Temperature Retrievals Using High Accuracy Infrared Radiiometers on Ships of Opportunity

    Science.gov (United States)

    Minnett, P. J.; Izaguirre, M. A.; Szcszodrak, M.; Williams, E.; Reynolds, R. M.

    2015-12-01

    The assessment of errors and uncertainties in satellite-derived SSTs can be achieved by comparisons with independent measurements of skin SST of high accuracy. Such validation measurements are provided by well-calibrated infrared radiometers mounted on ships. The second generation of Marine-Atmospheric Emitted Radiance Interferometers (M-AERIs) have recently been developed and two are now deployed on cruise ships of Royal Caribbean Cruise Lines that operate in the Caribbean Sea, North Atlantic and Mediterranean Sea. In addition, two Infrared SST Autonomous Radiometers (ISARs) are mounted alternately on a vehicle transporter of NYK Lines that crosses the Pacific Ocean between Japan and the USA. Both M-AERIs and ISARs are self-calibrating radiometers having two internal blackbody cavities to provide at-sea calibration of the measured radiances, and the accuracy of the internal calibration is periodically determined by measurements of a NIST-traceable blackbody cavity in the laboratory. This provides SI-traceability for the at-sea measurements. It is anticipated that these sensors will be deployed during the next several years and will be available for the validation of the SLSTRs on Sentinel-3a and -3b.

  2. Accuracy of the field triage protocol in selecting severely injured patients after high energy trauma.

    Science.gov (United States)

    van Laarhoven, J J E M; Lansink, K W W; van Heijl, M; Lichtveld, R A; Leenen, L P H

    2014-05-01

    For optimal treatment of trauma patients it is of great importance to identify patients who are at risk for severe injuries. The Dutch field triage protocol for trauma patients, the LPA (National Protocol of Ambulance Services), is designed to get the right patient, in the right time, to the right hospital. Purpose of this study was to determine diagnostic accuracy and compliance of this triage protocol. Triage criteria were categorised into physiological condition (P), mechanism of trauma (M) and injury type (I). A retrospective analysis of prospectively collected data of all high-energy trauma patients from 2008 to 2011 in the region Central Netherlands is performed. Diagnostic parameters (sensitivity, specificity, negative predictive value, positive predictive value) of the field triage protocol for selecting severely injured patients were calculated including rates of under- and overtriage. Undertriage was defined as the proportion of severely injured patients (Injury Severity Score (ISS)≥16) who were transported to a level two or three trauma care centre. Overtriage was defined as the proportion of non-severely injured patients (ISSprotocol was 89.1% (95% confidence interval (CI) 84.4-92.6) and 60.5% (95% CI 57.9-63.1), respectively. The overall rate of undertriage was 10.9% (95%CI 7.4-15.7) and the overall rate of overtriage was 39.5% (95%CI 36.9-42.1). These rates were 16.5% and 37.7%, respectively for patients with M+I-P-. Compliance to the triage protocol for patients with M+I-P- was 78.7%. Furthermore, compliance in patients with either a positive I+ or positive P+ was 91.2%. The overall rate of undertriage (10.8%) was mainly influenced by a high rate of undertriage in the group of patients with only a positive mechanism criterion, therefore showing low diagnostic accuracy in selecting severely injured patients. As a consequence these patients with severe injury are undetected using the current triage protocol. As it has been shown that severely injured

  3. Comparative analysis of the processing accuracy of high strength metal sheets by AWJ, laser and plasma

    Science.gov (United States)

    Radu, M. C.; Schnakovszky, C.; Herghelegiu, E.; Tampu, N. C.; Zichil, V.

    2016-08-01

    Experimental tests were carried out on two high-strength steel materials (Ramor 400 and Ramor 550). Quantification of the dimensional accuracy was achieved by measuring the deviations from some geometric parameters of part (two lengths and two radii). It was found that in case of Ramor 400 steel, at the jet inlet, the deviations from the part radii are quite small for all the three analysed processes. Instead for the linear dimensions, the deviations are small only in case of laser cutting. At the jet outlet, the deviations raised in small amount compared to those obtained at the jet inlet for both materials as well as for all the three processes. Related to Ramor 550 steel, at the jet inlet the deviations from the part radii are very small in case of AWJ and laser cutting but larger in case of plasma cutting. At the jet outlet, the deviations from the part radii are very small for all processes; in case of linear dimensions, there was obtained very small deviations only in the case of laser processing, the other two processes leading to very large deviations.

  4. Accuracy of Intraocular Lens Power Calculation Formulas for Highly Myopic Eyes

    Science.gov (United States)

    Zhang, Yichi; Liang, Xiao Ying; Liu, Shu; Lee, Jacky W. Y.; Bhaskar, Srinivasan; Lam, Dennis S. C.

    2016-01-01

    Purpose. To evaluate and compare the accuracy of different intraocular lens (IOL) power calculation formulas for eyes with an axial length (AL) greater than 26.00 mm. Methods. This study reviewed 407 eyes of 219 patients with AL longer than 26.0 mm. The refractive prediction errors of IOL power calculation formulas (SRK/T, Haigis, Holladay, Hoffer Q, and Barrett Universal II) using User Group for Laser Interference Biometry (ULIB) constants were evaluated and compared. Results. One hundred seventy-one eyes were enrolled. The Barrett Universal II formula had the lowest mean absolute error (MAE) and SRK/T and Haigis had similar MAE, and the statistical highest MAE were seen with the Holladay and Hoffer Q formulas. The interquartile range of the Barrett Universal II formula was also the lowest among all the formulas. The Barrett Universal II formulas yielded the highest percentage of eyes within ±1.0 D and ±0.5 D of the target refraction in this study (97.24% and 79.56%, resp.). Conclusions. Barrett Universal II formula produced the lowest predictive error and the least variable predictive error compared with the SRK/T, Haigis, Holladay, and Hoffer Q formulas. For high myopic eyes, the Barrett Universal II formula may be a more suitable choice. PMID:27119018

  5. Accuracy of Intraocular Lens Power Calculation Formulas for Highly Myopic Eyes

    Directory of Open Access Journals (Sweden)

    Yichi Zhang

    2016-01-01

    Full Text Available Purpose. To evaluate and compare the accuracy of different intraocular lens (IOL power calculation formulas for eyes with an axial length (AL greater than 26.00 mm. Methods. This study reviewed 407 eyes of 219 patients with AL longer than 26.0 mm. The refractive prediction errors of IOL power calculation formulas (SRK/T, Haigis, Holladay, Hoffer Q, and Barrett Universal II using User Group for Laser Interference Biometry (ULIB constants were evaluated and compared. Results. One hundred seventy-one eyes were enrolled. The Barrett Universal II formula had the lowest mean absolute error (MAE and SRK/T and Haigis had similar MAE, and the statistical highest MAE were seen with the Holladay and Hoffer Q formulas. The interquartile range of the Barrett Universal II formula was also the lowest among all the formulas. The Barrett Universal II formulas yielded the highest percentage of eyes within ±1.0 D and ±0.5 D of the target refraction in this study (97.24% and 79.56%, resp.. Conclusions. Barrett Universal II formula produced the lowest predictive error and the least variable predictive error compared with the SRK/T, Haigis, Holladay, and Hoffer Q formulas. For high myopic eyes, the Barrett Universal II formula may be a more suitable choice.

  6. Rapid, high-accuracy detection of strabismus and amblyopia using the pediatric vision scanner.

    Science.gov (United States)

    Loudon, Sjoukje E; Rook, Caitlin A; Nassif, Deborah S; Piskun, Nadya V; Hunter, David G

    2011-07-07

    Purpose. The Pediatric Vision Scanner (PVS) detects strabismus by identifying ocular fixation in both eyes simultaneously. This study was undertaken to assess the ability of the PVS to identify patients with amblyopia or strabismus, particularly anisometropic amblyopia with no measurable strabismus. Methods. The PVS test, administered from 40 cm and requiring 2.5 seconds of attention, generated a binocularity score (BIN, 0%-100%). We tested 154 patients and 48 controls between the ages of 2 and 18 years. BIN scores of amblyopic children and controls were measured, and 21 children received sequential PVS measurements to detect any changes in BIN resulting from amblyopia treatment. Results. With the pass/refer threshold set at BIN 60%, sensitivity and specificity were 96% for the detection of amblyopia or strabismus. Assuming a 5% prevalence of amblyopia or strabismus, the inferred positive and negative predictive values of the PVS were 56% and 100%, respectively. Fixation accuracy was significantly reduced in amblyopic eyes. In anisometropic amblyopia patients treated successfully, the BIN improved to 100%. Conclusions. The PVS identified children with amblyopia or strabismus with high sensitivity and specificity, while successful treatment restored normal BIN scores in amblyopic patients without strabismus. The results support the hypothesis that the PVS detects strabismus and amblyopia directly. Future strategies for screening by nonspecialists may thus be based on diagnostic detection of amblyopia and strabismus rather than the estimation of risk factors, allowing for rapid, accurate identification of children with amblyopia early in life when it is most amenable to treatment.

  7. A high accuracy broadband measurement system for time resolved complex bioimpedance measurements.

    Science.gov (United States)

    Kaufmann, S; Malhotra, A; Ardelt, G; Ryschka, M

    2014-06-01

    Bioimpedance measurements are useful tools in biomedical engineering and life science. Bioimpedance is the electrical impedance of living tissue and can be used in the analysis of various physiological parameters. Bioimpedance is commonly measured by injecting a small well known alternating current via surface electrodes into an object under test and measuring the resultant surface voltages. It is non-invasive, painless and has no known hazards. This work presents a field programmable gate array based high accuracy broadband bioimpedance measurement system for time resolved bioimpedance measurements. The system is able to measure magnitude and phase of complex impedances under test in a frequency range of about 10-500 kHz with excitation currents from 10 µA to 5 mA. The overall measurement uncertainties stay below 1% for the impedance magnitude and below 0.5° for the phase in most measurement ranges. Furthermore, the described system has a sample rate of up to 3840 impedance spectra per second. The performance of the bioimpedance measurement system is demonstrated with a resistor based system calibration and with measurements on biological samples.

  8. GRACE Data-based High Accuracy Global Static Earth's Gravity Field Model

    Directory of Open Access Journals (Sweden)

    CHEN Qiujie

    2016-04-01

    Full Text Available To recover the highly accurate static earth's gravity field by using GRACE satellite data is one of the hot topics in geodesy. Since linearization errors of dynamic approach quickly increase when extending satellite arc length, we established a modified dynamic approach for processing GRACE orbit and range-rate measurements in this paper, which treated orbit observations of the twin GRACE satellites as approximate values for linearization. Using the GRACE data spanning the period Jan. 2003 to Dec. 2010, containing satellite attitudes, orbits, range-rate, and non-conservative forces, we developed two global static gravity field models. One is the unconstrained solution called Tongji-Dyn01s complete to degree and order 180; the other one is the Tongji-Dyn01k model computed by using Kaula constraint. The comparisons between our models and those latest GRACE-only models (including the AIUB-GRACE03, the GGM05S, the ITSG-Grace2014k and the Tongji-GRACE01 published by different international groups, and the external validations with marine gravity anomalies from DTU13 product and height anomalies from GPS/levelling data, were performed in this study. The results demonstrate that the Tongji-Dyn01s has the same accuracy level with those of the latest GRACE-only models, while the Tongji-Dyn01k model is closer to the EIGEN6C2 than the other GRACE-only models as a whole.

  9. High Accuracy Extraction of Respiratory Sinus Arrhythmia with Statistical Processing using Normal Distribution

    Science.gov (United States)

    Numata, Takashi; Ogawa, Yutaro; Yoshida, Lui; Kotani, Kiyoshi; Jimbo, Yasuhiko

    The autonomic nervous system is important in maintaining homeostasis by mediating the opposing effects of the sympathetic and parasympathetic nervous activity on organs. Although it is known that the amplitude of RSA (Respiratory Sinus Arrhythmia) is an index of parasympathetic nervous activity, it is difficult to estimate that activity in real-time in everyday situations. It is partly caused by body motions and extrasystoles. Also, automatic recognition of the R-wave on electrocardiograms is required for real-time analysis of RSA amplitude, there is an unresolved problem of false recognition of the R-wave. In this paper, we propose a method to evaluate the amplitude of RSA accurately using statistical processing with probabilistic models. Then, we estimate parasympathetic nervous activity during body motion and isometric exercise to examine the validity of the method. As a result, using the proposed method, we demonstrate that the amplitude of RSA can be extracted with false recognition of the R-wave. In addition, an appropriate threshold for the estimate is one or five percent because waveforms of RSA amplitude do not follow the abrupt changes of the parasympathetic nervous activity evoked by isometric exercise with the threshold at ten percent. Furthermore, the method using normal distribution is found to be more appropriate than that of chi-square distribution for statistical processing. Therefore, we expect that the proposed method can evaluate parasympathetic nervous activity with high accuracy in everyday situations.

  10. Raman spectroscopic determination of the molecular constants of the hydrogen isotopologues with high accuracy

    Energy Technology Data Exchange (ETDEWEB)

    Krasch, Bennet; Mirz, Sebastian; Groessle, Robin [Karlsruhe Institute of Technology KIT (Germany). Institute for Technical Physics (ITEP), Tritium Laboratory Karlsruhe (TLK); Collaboration: KATRIN-Collaboration

    2016-07-01

    The interest in the thermodynamic properties of gases as the chemical equilibrium is faced by the challenge of time-consuming and technical extensive experimental setups. One possible solution is the derivation of these properties from the molecular constants. The rotational and vibrational movement of diatomic molecules, as the hydrogen isotopologues, is described by the concept of the rotational anharmonic oscillator. The molecular constants are the free parameters of this concept. Molecular constants themselves can be determined by measuring the line position of rotational and/or rotational transitions e.g. with Raman spectroscopy for hydrogen as it has been done since several years. In this contribution a Raman method was development to measure the molecular constant of the hydrogen isotopologues with high accuracy to obtain reliable results. But not only the method was development but also a complete measurement uncertainty budget was set up. The uncertainty budget contains all possible sources for uncertainties from the measurement period or the analysis process as well the contribution of each single uncertainty. The method and the uncertainty budget were exemplary tested on Deuterium.

  11. Fast-type high-accuracy universal polarimeter using charge-coupled device spectrometer

    Directory of Open Access Journals (Sweden)

    Akifumi Takanabe

    2017-02-01

    Full Text Available A fast, high-accuracy universal polarimeter was developed using a charge-coupled device (CCD spectrometer (CCD-HAUP, to carry out simultaneous optical anisotropic (linear birefringence, LB; linear dichroism, LD and chiroptical (circular birefringence, CB; circular dichroism, CD measurements on single crystals without any pretreatment, in the visible region between 400–680 nm. The principle of the HAUP method is to measure the intensities of emergent light passing through a polarizer, a crystal sample, and then an analyzer, as the azimuth angles of the polarizer and analyzer are independently altered. The CCD-HAUP has the unique feature that white transmitted light intensity can be measured using a CCD spectrometer, compared with the generalized HAUP (G-HAUP system in which monochromatic transmitted light is measured using a photomultiplier. The CCD-HAUP measurements across the entire wavelength region are completed within the G-HAUP measurement time for a single wavelength. The CCD-HAUP drastically reduces the measurement time for a dataset to only 1.5 h, from the 24 h required for the G-HAUP system. LB, LD, CB, and CD measurements of single crystals of α-quartz and enantiomeric photomechanical salicylidenephenylethylamines before, during, and after ultraviolet light irradiation show results comparable to those obtained using the G-HAUP system. The newly developed system is very effective for samples susceptible to degradation induced by external stimuli, such as light and heat.

  12. Statistical downscaling of precipitation using local regression and high accuracy surface modeling method

    Science.gov (United States)

    Zhao, Na; Yue, Tianxiang; Zhou, Xun; Zhao, Mingwei; Liu, Yu; Du, Zhengping; Zhang, Lili

    2017-07-01

    Downscaling precipitation is required in local scale climate impact studies. In this paper, a statistical downscaling scheme was presented with a combination of geographically weighted regression (GWR) model and a recently developed method, high accuracy surface modeling method (HASM). This proposed method was compared with another downscaling method using the Coupled Model Intercomparison Project Phase 5 (CMIP5) database and ground-based data from 732 stations across China for the period 1976-2005. The residual which was produced by GWR was modified by comparing different interpolators including HASM, Kriging, inverse distance weighted method (IDW), and Spline. The spatial downscaling from 1° to 1-km grids for period 1976-2005 and future scenarios was achieved by using the proposed downscaling method. The prediction accuracy was assessed at two separate validation sites throughout China and Jiangxi Province on both annual and seasonal scales, with the root mean square error (RMSE), mean relative error (MRE), and mean absolute error (MAE). The results indicate that the developed model in this study outperforms the method that builds transfer function using the gauge values. There is a large improvement in the results when using a residual correction with meteorological station observations. In comparison with other three classical interpolators, HASM shows better performance in modifying the residual produced by local regression method. The success of the developed technique lies in the effective use of the datasets and the modification process of the residual by using HASM. The results from the future climate scenarios show that precipitation exhibits overall increasing trend from T1 (2011-2040) to T2 (2041-2070) and T2 to T3 (2071-2100) in RCP2.6, RCP4.5, and RCP8.5 emission scenarios. The most significant increase occurs in RCP8.5 from T2 to T3, while the lowest increase is found in RCP2.6 from T2 to T3, increased by 47.11 and 2.12 mm, respectively.

  13. Statistical downscaling of precipitation using local regression and high accuracy surface modeling method

    Science.gov (United States)

    Zhao, Na; Yue, Tianxiang; Zhou, Xun; Zhao, Mingwei; Liu, Yu; Du, Zhengping; Zhang, Lili

    2016-03-01

    Downscaling precipitation is required in local scale climate impact studies. In this paper, a statistical downscaling scheme was presented with a combination of geographically weighted regression (GWR) model and a recently developed method, high accuracy surface modeling method (HASM). This proposed method was compared with another downscaling method using the Coupled Model Intercomparison Project Phase 5 (CMIP5) database and ground-based data from 732 stations across China for the period 1976-2005. The residual which was produced by GWR was modified by comparing different interpolators including HASM, Kriging, inverse distance weighted method (IDW), and Spline. The spatial downscaling from 1° to 1-km grids for period 1976-2005 and future scenarios was achieved by using the proposed downscaling method. The prediction accuracy was assessed at two separate validation sites throughout China and Jiangxi Province on both annual and seasonal scales, with the root mean square error (RMSE), mean relative error (MRE), and mean absolute error (MAE). The results indicate that the developed model in this study outperforms the method that builds transfer function using the gauge values. There is a large improvement in the results when using a residual correction with meteorological station observations. In comparison with other three classical interpolators, HASM shows better performance in modifying the residual produced by local regression method. The success of the developed technique lies in the effective use of the datasets and the modification process of the residual by using HASM. The results from the future climate scenarios show that precipitation exhibits overall increasing trend from T1 (2011-2040) to T2 (2041-2070) and T2 to T3 (2071-2100) in RCP2.6, RCP4.5, and RCP8.5 emission scenarios. The most significant increase occurs in RCP8.5 from T2 to T3, while the lowest increase is found in RCP2.6 from T2 to T3, increased by 47.11 and 2.12 mm, respectively.

  14. Geometric Accuracy Investigations of SEVIRI High Resolution Visible (HRV) Level 1.5 Imagery

    National Research Council Canada - National Science Library

    Sultan Kocaman Aksakal

    2013-01-01

    .... In a joint project between the Swiss GCOS Office and ETH Zurich, geometric accuracy and temporal stability of 1-km resolution HRV channel imagery of SEVIRI have been evaluated over Switzerland...

  15. The regulatory benefits of high levels of affect perception accuracy: a process analysis of reactions to stressors in daily life.

    Science.gov (United States)

    Robinson, Michael D; Moeller, Sara K; Buchholz, Maria M; Boyd, Ryan L; Troop-Gordon, Wendy

    2012-08-01

    Individuals attuned to affective signals from the environment may possess an advantage in the emotion-regulation realm. In two studies (total n = 151), individual differences in affective perception accuracy were assessed in an objective, performance-based manner. Subsequently, the same individuals completed daily diary protocols in which daily stressor levels were reported as well as problematic states shown to be stress-reactive in previous studies. In both studies, individual differences in affect perception accuracy interacted with daily stressor levels to predict the problematic outcomes. Daily stressors precipitated problematic reactions--whether depressive feelings (study 1) or somatic symptoms (study 2)--at low levels of affect perception accuracy, but did not do so at high levels of affect perception accuracy. The findings support a regulatory view of such perceptual abilities. Implications for understanding emotion regulation processes, emotional intelligence, and individual differences in reactivity are discussed.

  16. [Accuracy of liquid-based cytology in diagnosis of high-grade squamous cervical intraepithelial neoplasia].

    Science.gov (United States)

    Li, Min; Mei, Ping; Luo, Dong-lan; Wang, Xiao-bing; Liu, Yan-hui

    2012-04-01

    To investigate factors affecting the diagnostic accuracy of cervical liquid-based cytology for high-grade squamous intraepithelial lesion (HSIL). A retrospective evaluation of cytological and histological slides was performed in 415 patients who had cytological HSIL between 2007 and 2010. Among 42 209 cases screened by ThinPrep liquid-based cytology, 415 cases (1.0%) of HSIL were eventually identified. The mean age of HSIL patients was 41.6 years, and 30-49 years were the most common age group. Among 415 cases, 325 patients had available histological diagnosis as follows: 23 (7.1%) negative, 22 (6.8%) CIN1/HPV, 223 (68.6%) CIN2/CIN3, and 57 (17.5%) squamous cell carcinoma (SCC). The positive predictive values of HSIL to predict CIN2 (or higher grade of dysplasia) and CIN1 were 86.2% (280/325) and 92.9% (302/325), respectively. Inadequate biopsy, reactive glandular cells, islet atrophy, chemo/radiotherapy and others were responsible for the cytologically false-positive diagnosis. Fifty-seven (17.5%) cases of HSIL had a histological diagnosis of SCC. The possible causes of misdiagnosis were social factors, under-recognized cytological features of poorly-differentiated SCC and absence of typical diagnostic features in cytology slides. Cytology of HSIL has a high positive predictive value for the presence of CIN2/CIN3 and SCC. Cytologists and gynecologists should be aware of the diagnostic pitfalls that may lead to the discrepancy between cytology and histology.

  17. Achieving numerical accuracy and high performance using recursive tile LU factorization with partial pivoting

    KAUST Repository

    Dongarra, Jack

    2013-09-18

    The LU factorization is an important numerical algorithm for solving systems of linear equations in science and engineering and is a characteristic of many dense linear algebra computations. For example, it has become the de facto numerical algorithm implemented within the LINPACK benchmark to rank the most powerful supercomputers in the world, collected by the TOP500 website. Multicore processors continue to present challenges to the development of fast and robust numerical software due to the increasing levels of hardware parallelism and widening gap between core and memory speeds. In this context, the difficulty in developing new algorithms for the scientific community resides in the combination of two goals: achieving high performance while maintaining the accuracy of the numerical algorithm. This paper proposes a new approach for computing the LU factorization in parallel on multicore architectures, which not only improves the overall performance but also sustains the numerical quality of the standard LU factorization algorithm with partial pivoting. While the update of the trailing submatrix is computationally intensive and highly parallel, the inherently problematic portion of the LU factorization is the panel factorization due to its memory-bound characteristic as well as the atomicity of selecting the appropriate pivots. Our approach uses a parallel fine-grained recursive formulation of the panel factorization step and implements the update of the trailing submatrix with the tile algorithm. Based on conflict-free partitioning of the data and lockless synchronization mechanisms, our implementation lets the overall computation flow naturally without contention. The dynamic runtime system called QUARK is then able to schedule tasks with heterogeneous granularities and to transparently introduce algorithmic lookahead. The performance results of our implementation are competitive compared to the currently available software packages and libraries. For example

  18. Direct Georeferencing : a New Standard in Photogrammetry for High Accuracy Mapping

    Science.gov (United States)

    Rizaldy, A.; Firdaus, W.

    2012-07-01

    Direct georeferencing is a new method in photogrammetry, especially in the digital camera era. Theoretically, this method does not require ground control points (GCP) and the Aerial Triangulation (AT), to process aerial photography into ground coordinates. Compared with the old method, this method has three main advantages: faster data processing, simple workflow and less expensive project, at the same accuracy. Direct georeferencing using two devices, GPS and IMU. GPS recording the camera coordinates (X, Y, Z), and IMU recording the camera orientation (omega, phi, kappa). Both parameters merged into Exterior Orientation (EO) parameter. This parameters required for next steps in the photogrammetric projects, such as stereocompilation, DSM generation, orthorectification and mosaic. Accuracy of this method was tested on topographic map project in Medan, Indonesia. Large-format digital camera Ultracam X from Vexcel is used, while the GPS / IMU is IGI AeroControl. 19 Independent Check Point (ICP) were used to determine the accuracy. Horizontal accuracy is 0.356 meters and vertical accuracy is 0.483 meters. Data with this accuracy can be used for 1:2.500 map scale project.

  19. HIGH ACCURACY FINITE VOLUME ELEMENT METHOD FOR TWO-POINT BOUNDARY VALUE PROBLEM OF SECOND ORDER ORDINARY DIFFERENTIAL EQUATIONS

    Institute of Scientific and Technical Information of China (English)

    王同科

    2002-01-01

    In this paper, a high accuracy finite volume element method is presented for two-point boundary value problem of second order ordinary differential equation, which differs fromthe high order generalized difference methods. It is proved that the method has optimal order er-ror estimate O(h3) in H1 norm. Finally, two examples show that the method is effective.

  20. Numerical simulation for accuracy of velocity analysis in small-scale high-resolution marine multichannel seismic technology

    Science.gov (United States)

    Luo, Di; Cai, Feng; Wu, Zhiqiang

    2017-06-01

    When used with large energy sparkers, marine multichannel small-scale high-resolution seismic detection technology has a high resolution, high-detection precision, a wide applicable range, and is very flexible. Positive results have been achieved in submarine geological research, particularly in the investigation of marine gas hydrates. However, the amount of traveltime difference information is reduced for the velocity analysis under conditions of a shorter spread length, thus leading to poorer focusing of the velocity spectrum energy group and a lower accuracy of the velocity analysis. It is thus currently debatable whether the velocity analysis accuracy of short-arrangement multichannel seismic detection technology is able to meet the requirements of practical application in natural gas hydrate exploration. Therefore, in this study the bottom boundary of gas hydrates (Bottom Simulating Reflector, BSR) is used to conduct numerical simulation to discuss the accuracy of the velocity analysis related to such technology. Results show that a higher dominant frequency and smaller sampling interval are not only able to improve the seismic resolution, but they also compensate for the defects of the short-arrangement, thereby improving the accuracy of the velocity analysis. In conclusion, the accuracy of the velocity analysis in this small-scale, high-resolution, multi-channel seismic detection technology meets the requirements of natural gas hydrate exploration.

  1. Towards Building Reliable, High-Accuracy Solar Irradiance Database For Arid Climates

    Science.gov (United States)

    Munawwar, S.; Ghedira, H.

    2012-12-01

    Middle East's growing interest in renewable energy has led to increased activity in solar technology development with the recent commissioning of several utility-scale solar power projects and many other commercial installations across the Arabian Peninsula. The region, lying in a virtually rainless sunny belt with a typical daily average solar radiation exceeding 6 kWh/m2, is also one of the most promising candidates for solar energy deployment. However, it is not the availability of resource, but its characterization and reasonably accurate assessment that determines the application potential. Solar irradiance, magnitude and variability inclusive, is the key input in assessing the economic feasibility of a solar system. The accuracy of such data is of critical importance for realistic on-site performance estimates. This contribution aims to identify the key stages in developing a robust solar database for desert climate by focusing on the challenges that an arid environment presents to parameterization of solar irradiance attenuating factors. Adjustments are proposed based on the currently available resource assessment tools to produce high quality data for assessing bankability. Establishing and maintaining ground solar irradiance measurements is an expensive affair and fairly limited in time (recently operational) and space (fewer sites) in the Gulf region. Developers within solar technology industry, therefore, rely on solar radiation models and satellite-derived data for prompt resource assessment needs. It is imperative that such estimation tools are as accurate as possible. While purely empirical models have been widely researched and validated in the Arabian Peninsula's solar modeling history, they are known to be intrinsically site-specific. A primal step to modeling is an in-depth understanding of the region's climate, identifying the key players attenuating radiation and their appropriate characterization to determine solar irradiance. Physical approach

  2. Finite-element solution of the coupled-channel Schrödinger equation using high-order accuracy approximations

    Science.gov (United States)

    Abrashkevich, A. G.; Abrashkevich, D. G.; Kaschiev, M. S.; Puzynin, I. V.

    1995-01-01

    The finite element method (FEM) is applied to solve the bound state (Sturm-Liouville) problem for systems of ordinary linear second-order differential equations. The convergence, accuracy and the range of applicability of the high-order FEM approximations (up to tenth order) are studied systematically on the basis of numerical experiments for a wide set of quantum-mechanical problems. The analytical and tabular forms of giving the coefficients of differential equations are considered. The Dirichlet and Neumann boundary conditions are discussed. It is shown that the use of the FEM high-order accuracy approximations considerably increases the accuracy of the FE solutions with substantial reduction of the requirements on the computational resources. The results of the FEM calculations for various quantum-mechanical problems dealing with different types of potentials used in atomic and molecular calculations (including the hydrogen atom in a homogeneous magnetic field) are shown to be well converged and highly accurate.

  3. Automated, high accuracy classification of Parkinsonian disorders: a pattern recognition approach.

    Directory of Open Access Journals (Sweden)

    Andre F Marquand

    Full Text Available Progressive supranuclear palsy (PSP, multiple system atrophy (MSA and idiopathic Parkinson's disease (IPD can be clinically indistinguishable, especially in the early stages, despite distinct patterns of molecular pathology. Structural neuroimaging holds promise for providing objective biomarkers for discriminating these diseases at the single subject level but all studies to date have reported incomplete separation of disease groups. In this study, we employed multi-class pattern recognition to assess the value of anatomical patterns derived from a widely available structural neuroimaging sequence for automated classification of these disorders. To achieve this, 17 patients with PSP, 14 with IPD and 19 with MSA were scanned using structural MRI along with 19 healthy controls (HCs. An advanced probabilistic pattern recognition approach was employed to evaluate the diagnostic value of several pre-defined anatomical patterns for discriminating the disorders, including: (i a subcortical motor network; (ii each of its component regions and (iii the whole brain. All disease groups could be discriminated simultaneously with high accuracy using the subcortical motor network. The region providing the most accurate predictions overall was the midbrain/brainstem, which discriminated all disease groups from one another and from HCs. The subcortical network also produced more accurate predictions than the whole brain and all of its constituent regions. PSP was accurately predicted from the midbrain/brainstem, cerebellum and all basal ganglia compartments; MSA from the midbrain/brainstem and cerebellum and IPD from the midbrain/brainstem only. This study demonstrates that automated analysis of structural MRI can accurately predict diagnosis in individual patients with Parkinsonian disorders, and identifies distinct patterns of regional atrophy particularly useful for this process.

  4. Functional knowledge transfer for high-accuracy prediction of under-studied biological processes.

    Directory of Open Access Journals (Sweden)

    Christopher Y Park

    Full Text Available A key challenge in genetics is identifying the functional roles of genes in pathways. Numerous functional genomics techniques (e.g. machine learning that predict protein function have been developed to address this question. These methods generally build from existing annotations of genes to pathways and thus are often unable to identify additional genes participating in processes that are not already well studied. Many of these processes are well studied in some organism, but not necessarily in an investigator's organism of interest. Sequence-based search methods (e.g. BLAST have been used to transfer such annotation information between organisms. We demonstrate that functional genomics can complement traditional sequence similarity to improve the transfer of gene annotations between organisms. Our method transfers annotations only when functionally appropriate as determined by genomic data and can be used with any prediction algorithm to combine transferred gene function knowledge with organism-specific high-throughput data to enable accurate function prediction. We show that diverse state-of-art machine learning algorithms leveraging functional knowledge transfer (FKT dramatically improve their accuracy in predicting gene-pathway membership, particularly for processes with little experimental knowledge in an organism. We also show that our method compares favorably to annotation transfer by sequence similarity. Next, we deploy FKT with state-of-the-art SVM classifier to predict novel genes to 11,000 biological processes across six diverse organisms and expand the coverage of accurate function predictions to processes that are often ignored because of a dearth of annotated genes in an organism. Finally, we perform in vivo experimental investigation in Danio rerio and confirm the regulatory role of our top predicted novel gene, wnt5b, in leftward cell migration during heart development. FKT is immediately applicable to many bioinformatics

  5. Autotaxin activity has a high accuracy to diagnose intrahepatic cholestasis of pregnancy.

    Science.gov (United States)

    Kremer, Andreas E; Bolier, Ruth; Dixon, Peter H; Geenes, Victoria; Chambers, Jenny; Tolenaars, Dagmar; Ris-Stalpers, Carrie; Kaess, Bernhard M; Rust, Christian; van der Post, Joris A; Williamson, Catherine; Beuers, Ulrich; Oude Elferink, Ronald P J

    2015-04-01

    Intrahepatic cholestasis of pregnancy (ICP) is defined by pruritus, elevated total fasting serum bile salts (TBS) and transaminases, and an increased risk of adverse fetal outcome. An accurate diagnostic marker is needed. Increased serum autotaxin correlates with cholestasis-associated pruritus. We aimed at unraveling the diagnostic accuracy of autotaxin in ICP. Serum samples and placental tissue were collected from 44 women with uncomplicated pregnancies and 105 with pruritus and/or elevated serum transaminases. Autotaxin serum levels were quantified enzymatically and by Western blotting, autotaxin gene expression by quantitative PCR. Serum autotaxin was increased in ICP (mean ± SD: 43.5 ± 18.2 nmol ml(-1)min(-1), n=55, ppregnancy (16.8 ± 6.7 nmol ml(-1)min(-1), n=33), pre-eclampsia complicated by HELLP-syndrome (16.8 ± 8.9 nmol ml(-1)min(-1), n=17), and pregnant controls (19.6 ± 5.7 nmol ml(-1)min(-1), n=44). Longitudinal analysis during pregnancy revealed a marked rise in serum autotaxin with onset of ICP-related pruritus. Serum autotaxin was increased in women taking oral contraceptives. Increased serum autotaxin during ICP was not associated with increased autotaxin mRNA in placenta. With a cut-off value of 27.0 nmol ml(-1)min(-1), autotaxin had an excellent sensitivity and specificity in distinguishing ICP from other pruritic disorders or pre-eclampsia/HELLP-syndrome. Serum autotaxin displayed no circadian rhythm and was not influenced by food intake. Increased serum autotaxin activity represents a highly sensitive, specific and robust diagnostic marker of ICP, distinguishing ICP from other pruritic disorders of pregnancy and pregnancy-related liver diseases. Pregnancy and oral contraception increase serum autotaxin to a much lesser extent than ICP. Copyright © 2014 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.

  6. High accuracy solution of bi-directional wave propagation in continuum mechanics

    Science.gov (United States)

    Mulloth, Akhil; Sawant, Nilesh; Haider, Ijlal; Sharma, Nidhi; Sengupta, Tapan K.

    2015-10-01

    Solution of partial differential equations by numerical method is strongly affected due to numerical errors, which are caused mainly by deviation of numerical dispersion relation from the physical dispersion relation. To quantify and control such errors and obtain high accuracy solutions, we consider a class of problems which involve second derivative of unknowns with respect to time. Here, we analyse numerical metrics such as the numerical group velocity, numerical phase speed and the numerical amplification factor for different methods in solving the model bi-directional wave equation (BDWE). Such equations can be solved directly, for example, by Runge-Kutta-Nyström (RKN) method. Alternatively, the governing equation can be converted to a set of first order in time equations and then using four-stage fourth order Runge-Kutta (RK4) method for time integration. Spatial discretisation considered are the classical second and fourth order central difference schemes, along with Lele's central compact scheme for evaluating second derivatives. In another version, we have used Lele's scheme for evaluating first derivatives twice to obtain the second derivative. As BDWE represents non-dissipative, non-dispersive dynamics, we also consider the canonical problem of linearised rotating shallow water equation (LRSWE) in a new formulation involving second order derivative in time, which represents dispersive waves along with a stationary mode. The computations of LRSWE with RK4 and RKN methods for temporal discretisation and Lele's compact schemes for spatial discretisation are compared with computations performed with RK4 method for time discretisation and staggered compact scheme (SCS) for spatial discretisation by treating it as a set of three equations as reported in Rajpoot et al. (2012) [1].

  7. In-depth, high-accuracy proteomics of sea urchin tooth organic matrix

    Directory of Open Access Journals (Sweden)

    Mann Matthias

    2008-12-01

    Full Text Available Abstract Background The organic matrix contained in biominerals plays an important role in regulating mineralization and in determining biomineral properties. However, most components of biomineral matrices remain unknown at present. In sea urchin tooth, which is an important model for developmental biology and biomineralization, only few matrix components have been identified. The recent publication of the Strongylocentrotus purpuratus genome sequence rendered possible not only the identification of genes potentially coding for matrix proteins, but also the direct identification of proteins contained in matrices of skeletal elements by in-depth, high-accuracy proteomic analysis. Results We identified 138 proteins in the matrix of tooth powder. Only 56 of these proteins were previously identified in the matrices of test (shell and spine. Among the novel components was an interesting group of five proteins containing alanine- and proline-rich neutral or basic motifs separated by acidic glycine-rich motifs. In addition, four of the five proteins contained either one or two predicted Kazal protease inhibitor domains. The major components of tooth matrix were however largely identical to the set of spicule matrix proteins and MSP130-related proteins identified in test (shell and spine matrix. Comparison of the matrices of crushed teeth to intact teeth revealed a marked dilution of known intracrystalline matrix proteins and a concomitant increase in some intracellular proteins. Conclusion This report presents the most comprehensive list of sea urchin tooth matrix proteins available at present. The complex mixture of proteins identified may reflect many different aspects of the mineralization process. A comparison between intact tooth matrix, presumably containing odontoblast remnants, and crushed tooth matrix served to differentiate between matrix components and possible contributions of cellular remnants. Because LC-MS/MS-based methods directly

  8. High accuracy of arterial spin labeling perfusion imaging in differentiation of pilomyxoid from pilocytic astrocytoma

    Energy Technology Data Exchange (ETDEWEB)

    Nabavizadeh, S.A.; Assadsangabi, R.; Hajmomenian, M.; Vossough, A. [Perelman School of Medicine of the University of Pennsylvania, Department of Radiology, Children' s Hospital of Philadelphia, Philadelphia, PA (United States); Santi, M. [Perelman School of Medicine of the University of Pennsylvania, Department of Pathology, Children' s Hospital of Philadelphia, Philadelphia, PA (United States)

    2015-05-01

    Pilomyxoid astrocytoma (PMA) is a relatively new tumor entity which has been added to the 2007 WHO Classification of tumors of the central nervous system. The goal of this study is to utilize arterial spin labeling (ASL) perfusion imaging to differentiate PMA from pilocytic astrocytoma (PA). Pulsed ASL and conventional MRI sequences of patients with PMA and PA in the past 5 years were retrospectively evaluated. Patients with history of radiation or treatment with anti-angiogenic drugs were excluded. A total of 24 patients (9 PMA, 15 PA) were included. There were statistically significant differences between PMA and PA in mean tumor/gray matter (GM) cerebral blood flow (CBF) ratios (1.3 vs 0.4, p < 0.001) and maximum tumor/GM CBF ratio (2.3 vs 1, p < 0.001). Area under the receiver operating characteristic (ROC) curves for differentiation of PMA from PA was 0.91 using mean tumor CBF, 0.95 using mean tumor/GM CBF ratios, and 0.89 using maximum tumor/GM CBF. Using a threshold value of 0.91, the mean tumor/GM CBF ratio was able to diagnose PMA with 77 % sensitivity, 100 % specificity, and a threshold value of 0.7, provided 88 % sensitivity and 86 % specificity. There was no statistically significant difference between the two tumors in enhancement pattern (p = 0.33), internal architecture (p = 0.15), or apparent diffusion coefficient (ADC) values (p = 0.07). ASL imaging has high accuracy in differentiating PMA from PA. The result of this study may have important applications in prognostication and treatment planning especially in patients with less accessible tumors such as hypothalamic-chiasmatic gliomas. (orig.)

  9. High Resolution Ice Surface of the Ross Ice Shelf: Accuracy and Links to Basal Processes

    Science.gov (United States)

    Starke, S. E.

    2015-12-01

    We use airborne laser altimetry data from IcePod and IceBridge to map the surface across the Ross Ice Shelf in Antarctica. Laser altimetry and radar data is analyzed from the IcePod 2014 and 2015 field campaigns as well as IceBridge 2013. Icepod is a multi sensor suite that includes ice penetrating radars, a swath scanning laser, visible and IR cameras as well as GPS mounted on a LC-130. Using shallow ice radar data from both IcePod and IceBridge we identify the base of the ice shelf. Across the shelf we observe distinct areas of high reflectivity in the radar data suggesting basal crevassing. In some regions, the basal reflector is not well defined. Laser altimetry profiles correlate surface morphology with features at the base including basal crevasses and marine ice formed by freezing on to the base of the ice shelf. Building Digital Elevation Models (DEMs) from the laser altimetry data, we investigate the relationship between the surface expressions of these ice shelf dynamics including thickness changes, potential sites of marine ice at the base and basal morphology in regions where a well defined basal reflector does not exist in the radar profiles. We present accuracy of the IcePod laser altimetry dataset using ground control points and GPS grids from Greenland and Antarctica as well as Photogrammetric DEMs. Our laser altimetry analysis resolves sub-meter surface features which, combined with coincident radar, provides a link between basal processes and their surface expressions.

  10. The research of digital circuit system for high accuracy CCD of portable Raman spectrometer

    Science.gov (United States)

    Yin, Yu; Cui, Yongsheng; Zhang, Xiuda; Yan, Huimin

    2013-08-01

    The Raman spectrum technology is widely used for it can identify various types of molecular structure and material. The portable Raman spectrometer has become a hot direction of the spectrometer development nowadays for its convenience in handheld operation and real-time detection which is superior to traditional Raman spectrometer with heavy weight and bulky size. But there is still a gap for its measurement sensitivity between portable and traditional devices. However, portable Raman Spectrometer with Shell-Isolated Nanoparticle-Enhanced Raman Spectroscopy (SHINERS) technology can enhance the Raman signal significantly by several orders of magnitude, giving consideration in both measurement sensitivity and mobility. This paper proposed a design and implementation of driver and digital circuit for high accuracy CCD sensor, which is core part of portable spectrometer. The main target of the whole design is to reduce the dark current generation rate and increase signal sensitivity during the long integration time, and in the weak signal environment. In this case, we use back-thinned CCD image sensor from Hamamatsu Corporation with high sensitivity, low noise and large dynamic range. In order to maximize this CCD sensor's performance and minimize the whole size of the device simultaneously to achieve the project indicators, we delicately designed a peripheral circuit for the CCD sensor. The design is mainly composed with multi-voltage circuit, sequential generation circuit, driving circuit and A/D transition parts. As the most important power supply circuit, the multi-voltage circuits with 12 independent voltages are designed with reference power supply IC and set to specified voltage value by the amplifier making up the low-pass filter, which allows the user to obtain a highly stable and accurate voltage with low noise. What's more, to make our design easy to debug, CPLD is selected to generate sequential signal. The A/D converter chip consists of a correlated

  11. Millimeter-Wave Airborne Interferometry for High-accuracy Topography Mapping

    Science.gov (United States)

    Moller, D.; Hensley, S.; Wu, X.; Rodriguez, E.

    2011-12-01

    sensor geometry, bandwidth and number of channels needed for SWOT cal/val cannot be met within the framework of GLISTIN-A or a similar interface to UAVSAR. To address SWOT's cal/val requirements, the Ka-band SWOT Phenomenology Airborne Radar (KaSPAR) builds upon GLISTIN-A heritage and is the primary payload of the AirSWOT program. KaSPAR is a unique system with multiple temporal and cross-track baselines to fully characterize the scattering and statistics expected from SWOT, provide data for developing classification algorithms, and understanding instrument performance over the vast variety of scenes that SWOT will encounter. Furthermore a >5km swath high-accuracy WSE mapping capability provides the framework to translate traditional point or profile measurements to the spatial framework that SWOT will measure. Specific measurements from the integrated AirSWOT assembly are 1) WSE maps over a 5km swath with <3cm mean error at 100m x 100m postings (for ocean surface at 6m/s wind speed), 2) 2-D slope maps derived from WSE maps and 3) shoreline delineation at 10m resolution. These measurements will be made at resolutions exceeding that of SWOT to better characterize corrections for the spaceborne sensor.

  12. HIGH-ACCURACY BAND TO BAND REGISTRATION METHOD FOR MULTI-SPECTRAL IMAGES OF HJ-1A/B

    Institute of Scientific and Technical Information of China (English)

    Lu Hao; Liu Tuanjie; Zhao Haiqing

    2012-01-01

    Band-to-band registration accuracy is an important parameter of multispectral data.A novel band-to-band registration approach with high precision is proposed for the multi-spectral images of HJ-1A/B.Firstly,the main causes resulted in misregistration are analyzed,and a high-order polynomial model is proposed.Secondly,a phase fringe filtering technique is employed to Phase Correlation Method based on Singular Value Decomposition (SVD-PCM) for reducing the noise in phase difference matrix.Then,experiments are carried out to build nonlinear registration models,and images of green band and red band are aligned to blue band with an accuracy of 0.1 pixels,while near infrared band with an accuracy of 0.2 pixels.

  13. High-Accuracy HLA Type Inference from Whole-Genome Sequencing Data Using Population Reference Graphs.

    Directory of Open Access Journals (Sweden)

    Alexander T Dilthey

    2016-10-01

    Full Text Available Genetic variation at the Human Leucocyte Antigen (HLA genes is associated with many autoimmune and infectious disease phenotypes, is an important element of the immunological distinction between self and non-self, and shapes immune epitope repertoires. Determining the allelic state of the HLA genes (HLA typing as a by-product of standard whole-genome sequencing data would therefore be highly desirable and enable the immunogenetic characterization of samples in currently ongoing population sequencing projects. Extensive hyperpolymorphism and sequence similarity between the HLA genes, however, pose problems for accurate read mapping and make HLA type inference from whole-genome sequencing data a challenging problem. We describe how to address these challenges in a Population Reference Graph (PRG framework. First, we construct a PRG for 46 (mostly HLA genes and pseudogenes, their genomic context and their characterized sequence variants, integrating a database of over 10,000 known allele sequences. Second, we present a sequence-to-PRG paired-end read mapping algorithm that enables accurate read mapping for the HLA genes. Third, we infer the most likely pair of underlying alleles at G group resolution from the IMGT/HLA database at each locus, employing a simple likelihood framework. We show that HLA*PRG, our algorithm, outperforms existing methods by a wide margin. We evaluate HLA*PRG on six classical class I and class II HLA genes (HLA-A, -B, -C, -DQA1, -DQB1, -DRB1 and on a set of 14 samples (3 samples with 2 x 100bp, 11 samples with 2 x 250bp Illumina HiSeq data. Of 158 alleles tested, we correctly infer 157 alleles (99.4%. We also identify and re-type two erroneous alleles in the original validation data. We conclude that HLA*PRG for the first time achieves accuracies comparable to gold-standard reference methods from standard whole-genome sequencing data, though high computational demands (currently ~30-250 CPU hours per sample remain a

  14. High-Accuracy HLA Type Inference from Whole-Genome Sequencing Data Using Population Reference Graphs.

    Science.gov (United States)

    Dilthey, Alexander T; Gourraud, Pierre-Antoine; Mentzer, Alexander J; Cereb, Nezih; Iqbal, Zamin; McVean, Gil

    2016-10-01

    Genetic variation at the Human Leucocyte Antigen (HLA) genes is associated with many autoimmune and infectious disease phenotypes, is an important element of the immunological distinction between self and non-self, and shapes immune epitope repertoires. Determining the allelic state of the HLA genes (HLA typing) as a by-product of standard whole-genome sequencing data would therefore be highly desirable and enable the immunogenetic characterization of samples in currently ongoing population sequencing projects. Extensive hyperpolymorphism and sequence similarity between the HLA genes, however, pose problems for accurate read mapping and make HLA type inference from whole-genome sequencing data a challenging problem. We describe how to address these challenges in a Population Reference Graph (PRG) framework. First, we construct a PRG for 46 (mostly HLA) genes and pseudogenes, their genomic context and their characterized sequence variants, integrating a database of over 10,000 known allele sequences. Second, we present a sequence-to-PRG paired-end read mapping algorithm that enables accurate read mapping for the HLA genes. Third, we infer the most likely pair of underlying alleles at G group resolution from the IMGT/HLA database at each locus, employing a simple likelihood framework. We show that HLA*PRG, our algorithm, outperforms existing methods by a wide margin. We evaluate HLA*PRG on six classical class I and class II HLA genes (HLA-A, -B, -C, -DQA1, -DQB1, -DRB1) and on a set of 14 samples (3 samples with 2 x 100bp, 11 samples with 2 x 250bp Illumina HiSeq data). Of 158 alleles tested, we correctly infer 157 alleles (99.4%). We also identify and re-type two erroneous alleles in the original validation data. We conclude that HLA*PRG for the first time achieves accuracies comparable to gold-standard reference methods from standard whole-genome sequencing data, though high computational demands (currently ~30-250 CPU hours per sample) remain a significant

  15. Accuracy analysis of continuous deformation monitoring using BeiDou Navigation Satellite System at middle and high latitudes in China

    Science.gov (United States)

    Jiang, Weiping; Xi, Ruijie; Chen, Hua; Xiao, Yugang

    2017-02-01

    As BeiDou Navigation Satellite System (BDS) has been operational in the whole Asia-Pacific region, it means a new GNSS system with a different satellite orbit structure will become available for deformation monitoring in the future. Conversely, GNSS deformation monitoring data are always processed with a regular interval to form displacement time series for deformation analysis, where the interval can neither be too long from the time perspective nor too short from the precision of determined displacements angle. In this paper, two experimental platforms were designed, with one being at mid-latitude and another at higher latitude in China. BDS data processing software was also developed for investigating the accuracy of continuous deformation monitoring using current in-orbit BDS satellites. Data over 20 days at both platforms were obtained and were processed every 2, 4 and 6 h to generate 3 displacement time series for comparison. The results show that with the current in-orbit BDS satellites, in the mid-latitude area it is easy to achieve accuracy of 1 mm in horizontal component and 2-3 mm in vertical component; the accuracy could be further improved to approximately 1 mm in both horizontal and vertical directions when combined BDS/GPS measurements are employed. At higher latitude, however, the results are not as good as expected due to poor satellite geometry, even the 6 h solutions could only achieve accuracy of 4-6 and 6-10 mm in horizontal and vertical components, respectively, which implies that it may not be applicable to very high-precision deformation monitoring at high latitude using the current BDS. With the integration of BDS and GPS observations, however, in 4-h session, the accuracy can achieve 2 mm in horizontal component and 4 mm in vertical component, which would be an optimal choice for high-accuracy structural deformation monitoring at high latitude.

  16. Spectroscopy of H3+ based on a new high-accuracy global potential energy surface.

    Science.gov (United States)

    Polyansky, Oleg L; Alijah, Alexander; Zobov, Nikolai F; Mizus, Irina I; Ovsyannikov, Roman I; Tennyson, Jonathan; Lodi, Lorenzo; Szidarovszky, Tamás; Császár, Attila G

    2012-11-13

    The molecular ion H(3)(+) is the simplest polyatomic and poly-electronic molecular system, and its spectrum constitutes an important benchmark for which precise answers can be obtained ab initio from the equations of quantum mechanics. Significant progress in the computation of the ro-vibrational spectrum of H(3)(+) is discussed. A new, global potential energy surface (PES) based on ab initio points computed with an average accuracy of 0.01 cm(-1) relative to the non-relativistic limit has recently been constructed. An analytical representation of these points is provided, exhibiting a standard deviation of 0.097 cm(-1). Problems with earlier fits are discussed. The new PES is used for the computation of transition frequencies. Recently measured lines at visible wavelengths combined with previously determined infrared ro-vibrational data show that an accuracy of the order of 0.1 cm(-1) is achieved by these computations. In order to achieve this degree of accuracy, relativistic, adiabatic and non-adiabatic effects must be properly accounted for. The accuracy of these calculations facilitates the reassignment of some measured lines, further reducing the standard deviation between experiment and theory.

  17. Analysis of the plasmodium falciparum proteome by high-accuracy mass spectrometry

    DEFF Research Database (Denmark)

    Lasonder, Edwin; Ishihama, Yasushi; Andersen, Jens S;

    2002-01-01

    -accuracy (average deviation less than 0.02 Da at 1,000 Da) mass spectrometric proteome analysis of selected stages of the human malaria parasite Plasmodium falciparum. The analysis revealed 1,289 proteins of which 714 proteins were identified in asexual blood stages, 931 in gametocytes and 645 in gametes. The last...

  18. Literature survey of high-impact journals revealed reporting weaknesses in abstracts of diagnostic accuracy studies

    NARCIS (Netherlands)

    Korevaar, Daniël A; Cohen, Jérémie F; Hooft, Lotty; Bossuyt, Patrick M M

    2015-01-01

    OBJECTIVES: Informative journal abstracts are crucial for the identification and initial appraisal of studies. We aimed to evaluate the informativeness of abstracts of diagnostic accuracy studies. STUDY DESIGN AND SETTING: PubMed was searched for reports of studies that had evaluated the diagnostic

  19. The effect of moderate and high-intensity fatigue on groundstroke accuracy in expert and non-expert tennis players.

    Science.gov (United States)

    Lyons, Mark; Al-Nakeeb, Yahya; Hankey, Joanne; Nevill, Alan

    2013-01-01

    Exploring the effects of fatigue on skilled performance in tennis presents a significant challenge to the researcher with respect to ecological validity. This study examined the effects of moderate and high-intensity fatigue on groundstroke accuracy in expert and non-expert tennis players. The research also explored whether the effects of fatigue are the same regardless of gender and player's achievement motivation characteristics. 13 expert (7 male, 6 female) and 17 non-expert (13 male, 4 female) tennis players participated in the study. Groundstroke accuracy was assessed using the modified Loughborough Tennis Skills Test. Fatigue was induced using the Loughborough Intermittent Tennis Test with moderate (70%) and high-intensities (90%) set as a percentage of peak heart rate (attained during a tennis-specific maximal hitting sprint test). Ratings of perceived exertion were used as an adjunct to the monitoring of heart rate. Achievement goal indicators for each player were assessed using the 2 x 2 Achievement Goals Questionnaire for Sport in an effort to examine if this personality characteristic provides insight into how players perform under moderate and high-intensity fatigue conditions. A series of mixed ANOVA's revealed significant fatigue effects on groundstroke accuracy regardless of expertise. The expert players however, maintained better groundstroke accuracy across all conditions compared to the novice players. Nevertheless, in both groups, performance following high-intensity fatigue deteriorated compared to performance at rest and performance while moderately fatigued. Groundstroke accuracy under moderate levels of fatigue was equivalent to that at rest. Fatigue effects were also similar regardless of gender. No fatigue by expertise, or fatigue by gender interactions were found. Fatigue effects were also equivalent regardless of player's achievement goal indicators. Future research is required to explore the effects of fatigue on performance in tennis

  20. High-accuracy real-time automatic thresholding for centroid tracker

    Science.gov (United States)

    Zhang, Ye; Wang, Yanjie

    2006-01-01

    Many of the video image trackers today use the centroid as the tracking point. In engineering, a target's centroid is computed from a binary image to reduce the processing time. Hence thresholding of gray level image to binary image is a decisive step in centroid tracking. How to choose the feat thresholds in clutter is still an intractability problem unsolved today. This paper introduces a high-accuracy real-time automatic thresholding method for centroid tracker. It works well for variety types of target tracking in clutter. The core of this method is to get the entire information contained in the histogram, such as the number of the peaks, their height, position and other properties in the histogram. Combine with this histogram analysis; we can get several key pairs of peaks which can include the target and the background around it and use the method of Otsu to get intensity thresholds from them. According to the thresholds, we can gain the binary image and get the centroid from it. To track the target, the paper also suggests subjoining an eyeshot-window, just like our eyes focus on a target, we will not miss it unless it is out of our eyeshot, the impression will help us to extract the target in clutter and track it and we will wait its emergence since it has been covered. To obtain the impression, the paper offers a idea comes from the method of Snakes; it give a great help for us to get a glancing size, so that we can compare the size of the object in the current frame with the former. If the change is little, we consider the object has been tracked well. Otherwise, if the change is bigger than usual, we should analyze the inflection in the histogram to find out what happened to the object. In general, what we have to do is turning the analysis into codes for the tracker to determine a feat threshold. The paper will show the steps in detail. The paper also discusses the hardware architecture which can meet the speed requirement.

  1. High-accuracy, high-resolution gravity profiles from 2 years of the Geosat Exact Repeat Mission

    Science.gov (United States)

    Sandwell, David T.; Mcadoo, David C.

    1990-01-01

    Satellite altimeter data from the first 44 repeat cycles (2 years) of the Geosat Exact Repeat Mission (EWRM) were averaged to improve accuracy, resolution and coverage of the marine gravity field. Individual 17-day repeat cycles were first edited and differentiated, resulting in the along-track vertical deflection (i.e., gravity disturbance). To increase the signal-to-noise ratio, 44 of these cycles were then averaged to form a single highly accurate vertical deflection profile. The largest contribution to the vertical deflection error is short-wavelength altimeter noise and longer-wavelength oceanographic variability; the combined noise level is typically 6 microrad. Both types of noise are reduced by averaging many repeat cycles. Over most ocean areas the uncertainty of the average profile is less than 1 microrad which corresponds to 1 mgal of along-track gravity disturbance. However, in areas of seasonal ice coverage, its uncertainty can exceed 5 microrad. To assess the resolution of individual and average Geosat gravity profiles, the cross-spectral analysis technique was applied to repeat profiles. Individual Geosat repeat cycles are coherent (greater than 0.5) for wavelengths greater than about 30 km and become increasingly incoherent at shorter wavelengths.

  2. The Effects of Individual or Group Guidelines on the Calibration Accuracy and Achievement of High School Biology Students

    Science.gov (United States)

    Bol, Linda; Hacker, Douglas J.; Walck, Camilla C.; Nunnery, John A.

    2012-01-01

    A 2 x 2 factorial design was employed in a quasi-experiment to investigate the effects of guidelines in group or individual settings on the calibration accuracy and achievement of 82 high school biology students. Significant main effects indicated that calibration practice with guidelines and practice in group settings increased prediction and…

  3. Accuracy of High-Resolution MRI with Lumen Distention in Rectal Cancer Staging and Circumferential Margin Involvement Prediction

    Energy Technology Data Exchange (ETDEWEB)

    Iannicelli, Elsa; Di Renzo, Sara [Radiology Institute, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant' Andrea Hospital, Rome 00189 (Italy); Department of Surgical and Medical Sciences and Translational Medicine, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant' Andrea Hospital, Rome 00189 (Italy); Ferri, Mario [Department of Surgical and Medical Sciences and Translational Medicine, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant' Andrea Hospital, Rome 00189 (Italy); Pilozzi, Emanuela [Department of Clinical and Molecular Sciences, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant' Andrea Hospital, Rome 00189 (Italy); Di Girolamo, Marco; Sapori, Alessandra [Radiology Institute, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant' Andrea Hospital, Rome 00189 (Italy); Department of Surgical and Medical Sciences and Translational Medicine, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant' Andrea Hospital, Rome 00189 (Italy); Ziparo, Vincenzo [Department of Surgical and Medical Sciences and Translational Medicine, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant' Andrea Hospital, Rome 00189 (Italy); David, Vincenzo [Radiology Institute, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant' Andrea Hospital, Rome 00189 (Italy); Department of Surgical and Medical Sciences and Translational Medicine, Faculty of Medicine and Psychology, University of Rome, Sapienza, Sant' Andrea Hospital, Rome 00189 (Italy)

    2014-07-01

    To evaluate the accuracy of magnetic resonance imaging (MRI) with lumen distention for rectal cancer staging and circumferential resection margin (CRM) involvement prediction. Seventy-three patients with primary rectal cancer underwent high-resolution MRI with a phased-array coil performed using 60-80 mL room air rectal distention, 1-3 weeks before surgery. MRI results were compared to postoperative histopathological findings. The overall MRI T staging accuracy was calculated. CRM involvement prediction and the N staging, the accuracy, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were assessed for each T stage. The agreement between MRI and histological results was assessed using weighted-kappa statistics. The overall MRI accuracy for T staging was 93.6% (k = 0.85). The accuracy, sensitivity, specificity, PPV and NPV for each T stage were as follows: 91.8%, 86.2%, 95.5%, 92.6% and 91.3% for the group ≤ T2; 90.4%, 94.6%, 86.1%, 87.5% and 94% for T3; 98,6%, 85.7%, 100%, 100% and 98.5% for T4, respectively. The predictive CRM accuracy was 94.5% (k = 0.86); the sensitivity, specificity, PPV and NPV were 89.5%, 96.3%, 89.5%, and 96.3% respectively. The N staging accuracy was 68.49% (k = 0.4). MRI performed with rectal lumen distention has proved to be an effective technique both for rectal cancer staging and involved CRM predicting.

  4. Real-time displacement measurement with large range and high accuracy using sinusoidal phase modulating laser diode interferometer

    Institute of Scientific and Technical Information of China (English)

    Guotian He; Xiangzhao Wang; Aijun Zeng; Feng Tang; Bingjie Huang

    2007-01-01

    To resolve the conflict of large measurement range and high accuracy in the existing real-time displacement measurement laser diode (LD) interferometers, a novel real-time displacement measurement LD interferometry is proposed and its measurement principle is analyzed. By use of a new phase demodulation algorithm and a new phase compensation lgorithm of real-time phase unwrapping, the measurement accuracy is improved, and the measurement range is enlarged to a few wavelengths. In experiments, the peak-to-peak amplitude of the speaker vibration was 2361.7 nm, and the repeatability was 2.56 nm. The measurement time was less than 26μs.

  5. High-accuracy extrapolated ab initio thermochemistry. II. Minor improvements to the protocol and a vital simplification

    Science.gov (United States)

    Bomble, Yannick J.; Vázquez, Juana; Kállay, Mihály; Michauk, Christine; Szalay, Péter G.; Császár, Attila G.; Gauss, Jürgen; Stanton, John F.

    2006-08-01

    The recently developed high-accuracy extrapolated ab initio thermochemistry method for theoretical thermochemistry, which is intimately related to other high-precision protocols such as the Weizmann-3 and focal-point approaches, is revisited. Some minor improvements in theoretical rigor are introduced which do not lead to any significant additional computational overhead, but are shown to have a negligible overall effect on the accuracy. In addition, the method is extended to completely treat electron correlation effects up to pentuple excitations. The use of an approximate treatment of quadruple and pentuple excitations is suggested; the former as a pragmatic approximation for standard cases and the latter when extremely high accuracy is required. For a test suite of molecules that have rather precisely known enthalpies of formation {as taken from the active thermochemical tables of Ruscic and co-workers [Lecture Notes in Computer Science, edited by M. Parashar (Springer, Berlin, 2002), Vol. 2536, pp. 25-38; J. Phys. Chem. A 108, 9979 (2004)]}, the largest deviations between theory and experiment are 0.52, -0.70, and 0.51kJmol-1 for the latter three methods, respectively. Some perspective is provided on this level of accuracy, and sources of remaining systematic deficiencies in the approaches are discussed.

  6. SFOL Pulse: A High Accuracy DME Pulse for Alternative Aircraft Position and Navigation

    Directory of Open Access Journals (Sweden)

    Euiho Kim

    2017-09-01

    Full Text Available In the Federal Aviation Administration’s (FAA performance based navigation strategy announced in 2016, the FAA stated that it would retain and expand the Distance Measuring Equipment (DME infrastructure to ensure resilient aircraft navigation capability during the event of a Global Navigation Satellite System (GNSS outage. However, the main drawback of the DME as a GNSS back up system is that it requires a significant expansion of the current DME ground infrastructure due to its poor distance measuring accuracy over 100 m. The paper introduces a method to improve DME distance measuring accuracy by using a new DME pulse shape. The proposed pulse shape was developed by using Genetic Algorithms and is less susceptible to multipath effects so that the ranging error reduces by 36.0–77.3% when compared to the Gaussian and Smoothed Concave Polygon DME pulses, depending on noise environment.

  7. Friction compensation design based on state observer and adaptive law for high-accuracy positioning system

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Friction is one of the main factors that affect the positioning accuracy of motion system. Friction compensation based on friction model is usually adopted to eliminate the nonlinear effect of friction. This paper presents a proportional-plus-derivative (PD) feedback controller with a friction compensator based on LuGre friction model. We also design a state observer to observe the unknown state of LuGre friction model, and adopt a parameter adaptive law and off-line approximation to estimate the parameters of LuGre friction model. Comparative experiments are carried out among our proposed controller, PD controller with friction compensation based on classical friction model, and PD controller without friction compensation. Experimental results demonstrate that our proposed controller can achieve better performance, especially higher positioning accuracy.

  8. Ways to help Chinese Students in Senior High School improve language accuracy in writing

    Institute of Scientific and Technical Information of China (English)

    潘惠红

    2015-01-01

    <正>Introduction In Chinese ELT(English language teaching),as in other countries,both fluency and accuracy are considered important either in the teaching or assessment of writing.In this respect,the last decade has seen reforms in the College Entrance Examination in Guangdong Province.With two writing tasks being set as assessment,task one requires students to summarise Chinese language information into five English sentences while the

  9. A High-Accuracy Linear Conservative Difference Scheme for Rosenau-RLW Equation

    Directory of Open Access Journals (Sweden)

    Jinsong Hu

    2013-01-01

    Full Text Available We study the initial-boundary value problem for Rosenau-RLW equation. We propose a three-level linear finite difference scheme, which has the theoretical accuracy of Oτ2+h4. The scheme simulates two conservative properties of original problem well. The existence, uniqueness of difference solution, and a priori estimates in infinite norm are obtained. Furthermore, we analyze the convergence and stability of the scheme by energy method. At last, numerical experiments demonstrate the theoretical results.

  10. High-accuracy current measurement with low-cost shunts by means of dynamic error correction

    OpenAIRE

    Weßkamp, Patrick; Melbert, Joachim

    2016-01-01

    Measurement of electrical current is often performed by using shunt resistors. Thermal effects due to self-heating and ambient temperature variation limit the achievable accuracy, especially if low-cost shunt resistors with increased temperature coefficients are utilized. In this work, a compensation method is presented which takes static and dynamic temperature drift effects into account and provides a significant reduction of measurement error. A thermal model of the shunt...

  11. A high-accuracy optical linear algebra processor for finite element applications

    Science.gov (United States)

    Casasent, D.; Taylor, B. K.

    1984-01-01

    Optical linear processors are computationally efficient computers for solving matrix-matrix and matrix-vector oriented problems. Optical system errors limit their dynamic range to 30-40 dB, which limits their accuray to 9-12 bits. Large problems, such as the finite element problem in structural mechanics (with tens or hundreds of thousands of variables) which can exploit the speed of optical processors, require the 32 bit accuracy obtainable from digital machines. To obtain this required 32 bit accuracy with an optical processor, the data can be digitally encoded, thereby reducing the dynamic range requirements of the optical system (i.e., decreasing the effect of optical errors on the data) while providing increased accuracy. This report describes a new digitally encoded optical linear algebra processor architecture for solving finite element and banded matrix-vector problems. A linear static plate bending case study is described which quantities the processor requirements. Multiplication by digital convolution is explained, and the digitally encoded optical processor architecture is advanced.

  12. Will it Blend? Visualization and Accuracy Evaluation of High-Resolution Fuzzy Vegetation Maps

    Science.gov (United States)

    Zlinszky, A.; Kania, A.

    2016-06-01

    Instead of assigning every map pixel to a single class, fuzzy classification includes information on the class assigned to each pixel but also the certainty of this class and the alternative possible classes based on fuzzy set theory. The advantages of fuzzy classification for vegetation mapping are well recognized, but the accuracy and uncertainty of fuzzy maps cannot be directly quantified with indices developed for hard-boundary categorizations. The rich information in such a map is impossible to convey with a single map product or accuracy figure. Here we introduce a suite of evaluation indices and visualization products for fuzzy maps generated with ensemble classifiers. We also propose a way of evaluating classwise prediction certainty with "dominance profiles" visualizing the number of pixels in bins according to the probability of the dominant class, also showing the probability of all the other classes. Together, these data products allow a quantitative understanding of the rich information in a fuzzy raster map both for individual classes and in terms of variability in space, and also establish the connection between spatially explicit class certainty and traditional accuracy metrics. These map products are directly comparable to widely used hard boundary evaluation procedures, support active learning-based iterative classification and can be applied for operational use.

  13. High accuracy integrated global positioning system/inertial navigation system LDRD: Final report

    Energy Technology Data Exchange (ETDEWEB)

    Owen, T.E.; Meindl, M.A.; Fellerhoff, J.R.

    1997-03-01

    This report contains the results of a Sandia National Laboratories Directed Research and Development (LDRD) program to investigate the integration of Global Positioning System (GPS) and inertial navigation system (INS) technologies toward the goal of optimizing the navigational accuracy of the combined GPSANS system. The approach undertaken is to integrate the data from an INS, which has long term drifts, but excellent short term accuracy, with GPS carrier phase signal information, which is accurate to the sub-centimeter level, but requires continuous tracking of the GPS signals. The goal is to maintain a sub-meter accurate navigation solution while the vehicle is in motion by using the GPS measurements to estimate the INS navigation errors and then using the refined INS data to aid the GPS carrier phase cycle slip detection and correction and bridge dropouts in the GPS data. The work was expanded to look at GPS-based attitude determination, using multiple GPS receivers and antennas on a single platform, as a possible navigation aid. Efforts included not only the development of data processing algorithms and software, but also the collection and analysis of GPS and INS flight data aboard a Twin Otter aircraft. Finally, the application of improved navigation system accuracy to synthetic aperture radar (SAR) target location is examined.

  14. THE EFFECT OF MODERATE AND HIGH-INTENSITY FATIGUE ON GROUNDSTROKE ACCURACY IN EXPERT AND NON-EXPERT TENNIS PLAYERS

    Directory of Open Access Journals (Sweden)

    Mark Lyons

    2013-06-01

    Full Text Available Exploring the effects of fatigue on skilled performance in tennis presents a significant challenge to the researcher with respect to ecological validity. This study examined the effects of moderate and high-intensity fatigue on groundstroke accuracy in expert and non-expert tennis players. The research also explored whether the effects of fatigue are the same regardless of gender and player's achievement motivation characteristics. 13 expert (7 male, 6 female and 17 non-expert (13 male, 4 female tennis players participated in the study. Groundstroke accuracy was assessed using the modified Loughborough Tennis Skills Test. Fatigue was induced using the Loughborough Intermittent Tennis Test with moderate (70% and high-intensities (90% set as a percentage of peak heart rate (attained during a tennis-specific maximal hitting sprint test. Ratings of perceived exertion were used as an adjunct to the monitoring of heart rate. Achievement goal indicators for each player were assessed using the 2 x 2 Achievement Goals Questionnaire for Sport in an effort to examine if this personality characteristic provides insight into how players perform under moderate and high-intensity fatigue conditions. A series of mixed ANOVA's revealed significant fatigue effects on groundstroke accuracy regardless of expertise. The expert players however, maintained better groundstroke accuracy across all conditions compared to the novice players. Nevertheless, in both groups, performance following high-intensity fatigue deteriorated compared to performance at rest and performance while moderately fatigued. Groundstroke accuracy under moderate levels of fatigue was equivalent to that at rest. Fatigue effects were also similar regardless of gender. No fatigue by expertise, or fatigue by gender interactions were found. Fatigue effects were also equivalent regardless of player's achievement goal indicators. Future research is required to explore the effects of fatigue on

  15. Horizontal Positional Accuracy of Google Earth’s High-Resolution Imagery Archive

    Directory of Open Access Journals (Sweden)

    David Potere

    2008-12-01

    Full Text Available Google Earth now hosts high-resolution imagery that spans twenty percent of the Earth’s landmass and more than a third of the human population. This contemporary highresolution archive represents a significant, rapidly expanding, cost-free and largely unexploited resource for scientific inquiry. To increase the scientific utility of this archive, we address horizontal positional accuracy (georegistration by comparing Google Earth with Landsat GeoCover scenes over a global sample of 436 control points located in 109 cities worldwide. Landsat GeoCover is an orthorectified product with known absolute positional accuracy of less than 50 meters root-mean-squared error (RMSE. Relative to Landsat GeoCover, the 436 Google Earth control points have a positional accuracy of 39.7 meters RMSE (error magnitudes range from 0.4 to 171.6 meters. The control points derived from satellite imagery have an accuracy of 22.8 meters RMSE, which is significantly more accurate than the 48 control-points based on aerial photography (41.3 meters RMSE; t-test p-value < 0.01. The accuracy of control points in more-developed countries is 24.1 meters RMSE, which is significantly more accurate than the control points in developing countries (44.4 meters RMSE; t-test p-value < 0.01. These findings indicate that Google Earth highresolution imagery has a horizontal positional accuracy that is sufficient for assessing moderate-resolution remote sensing products across most of the world’s peri-urban areas.

  16. Error correction algorithm for high accuracy bio-impedance measurement in wearable healthcare applications.

    Science.gov (United States)

    Kubendran, Rajkumar; Lee, Seulki; Mitra, Srinjoy; Yazicioglu, Refet Firat

    2014-04-01

    Implantable and ambulatory measurement of physiological signals such as Bio-impedance using miniature biomedical devices needs careful tradeoff between limited power budget, measurement accuracy and complexity of implementation. This paper addresses this tradeoff through an extensive analysis of different stimulation and demodulation techniques for accurate Bio-impedance measurement. Three cases are considered for rigorous analysis of a generic impedance model, with multiple poles, which is stimulated using a square/sinusoidal current and demodulated using square/sinusoidal clock. For each case, the error in determining pole parameters (resistance and capacitance) is derived and compared. An error correction algorithm is proposed for square wave demodulation which reduces the peak estimation error from 9.3% to 1.3% for a simple tissue model. Simulation results in Matlab using ideal RC values show an average accuracy of for single pole and for two pole RC networks. Measurements using ideal components for a single pole model gives an overall and readings from saline phantom solution (primarily resistive) gives an . A Figure of Merit is derived based on ability to accurately resolve multiple poles in unknown impedance with minimal measurement points per decade, for given frequency range and supply current budget. This analysis is used to arrive at an optimal tradeoff between accuracy and power. Results indicate that the algorithm is generic and can be used for any application that involves resolving poles of an unknown impedance. It can be implemented as a post-processing technique for error correction or even incorporated into wearable signal monitoring ICs.

  17. A High-accuracy Approach to Pronunciation Prediction for Out-of-vocabulary English Word

    Institute of Scientific and Technical Information of China (English)

    WANG Hao; CHEN Gui-lin; XU Liang-xian

    2005-01-01

    Letter-to-Sound conversion is one of the fundamental issues in text-to-speech synthesis. In this paper, we address an approach to automatic prediction of word pronunciation. This approach combines example-based learning and dynamic-programming searching to predict sub-word pronunciation. Word pronunciation is formed by concatenating sub-word pronunciations. We conducted comparative experiments over a large-scale English dictionary. Experimental results show that this approach can achieve accuracy of 70.1%, which outperforms those published results.

  18. High accuracy wavelength locking of a DFB laser using tunable polarization interference filter

    Institute of Scientific and Technical Information of China (English)

    Xiyao Chen(陈曦曜); Jianping Xie(谢建平); Tianpeng Zhao(赵天鹏); Hai Ming(明海); Anting Wang(王安廷); Wencai Huang(黄文财); Liang Lü(吕亮); Lixin Xu(许立新)

    2003-01-01

    A temperature-tunable polarization interference filter (PIF) made of YVO4 crystal has been presented and applied for wavelength locking of a distributed feedback (DFB) semiconductor laser in dense wavelength-division-multiplexing (DWDM) optical communication systems. This new design offers a flexible way to monitor and then lock an operating wavelength of DFB laser to any preselected point without dead spots.The results show that the laser wavelength can be locked with accuracy better than ±0.01 nm with much relaxed requirement on temperature stability of the filter.

  19. High-accuracy mass determination of unstable cesium and barium isotopes

    CERN Document Server

    Ames, F; Beck, D; Bollen, G; De Saint-Simon, M; Jertz, R; Kluge, H J; Kohl, A; König, M; Lunney, M D; Martel, I; Moore, R B; Otto, T; Patyk, Z; Raimbault-Hartmann, H; Rouleau, G; Savard, G; Schark, E; Schwarz, S; Schweikhard, L; Stolzenberg, H; Szerypo, J

    1999-01-01

    Direct mass measurements of short-lived Cs and Ba isotopes have been performed with the tandem Penning trap mass spectrometer ISOLTRAP installed at the on-line isotope separator ISOLDE at CERN. Typically, a mass resolving power of 600 000 and an accuracy of $\\delta \\mbox{m} \\approx 13$ keV have been obtained. The masses of $^{123,124,126}$Ba and $^{122m}$Cs were measured for the first time. A least-squares adjustment has been performed and the experimental masses are compared with theoretical ones, particularly in the frame of a macroscopic-microscopic model.

  20. High-accuracy mass determination of neutron-rich rubidium and strontiumiIsotopes

    CERN Document Server

    Raimbault-Hartmann, H; Beck, D; Bollen, G; De Saint-Simon, M; Kluge, H J; König, M; Moore, R B; Schwarz, S; Savard, G; Szerypo, J

    2002-01-01

    The penning-trap mass spectrometer ISOLTRAP, installed at the on-line isotope separator ISOLDE at CERN, has been used to measure atomic masses of $^{88,89,90m,91,92,93,94}$Rb and $^{91- 95}$Sr. Using a resolving power of R $\\!\\scriptstyle\\approx$1 million a mass accuracy of typically 10 keV was achieved for all nuclides. Discrepancies with older data are analyzed and discussed, leading to corrections to those data. Together with the present ISOLTRAP data these corrected data have been used in the general mass adjustment.

  1. High-Accuracy Measurements of the Centre of Gravity of Avalanches in Proportional Chambers

    Science.gov (United States)

    Charpak, G.; Jeavons, A.; Sauli, F.; Stubbs, R.

    1973-09-24

    In a multiwire proportional chamber the avalanches occur close to the anode wires. The motion of the positive ions in the large electric fields at the vicinity of the wires induces fast-rising positive pulses on the surrounding electrodes. Different methods have been developed in order to determine the position of the centre of the avalanches. In the method we describe, the centre of gravity of the pulse distribution is measured directly. It seems to lead to an accuracy which is limited only by the stability of the spatial distribution of the avalanches generated by the process being measured.

  2. High-Accuracy Tracking Control of Robot Manipulators Using Time Delay Estimation and Terminal Sliding Mode

    Directory of Open Access Journals (Sweden)

    Maolin Jin

    2011-09-01

    Full Text Available A time delay estimation based general framework for trajectory tracking control of robot manipulators is presented. The controller consists of three elements: a time‐delay‐estimation element that cancels continuous nonlinearities of robot dynamics, an injecting element that endows desired error dynamics, and a correcting element that suppresses residual time delay estimation error caused by discontinuous nonlinearities. Terminal sliding mode is used for the correcting element to pursue fast convergence of the time delay estimation error. Implementation of proposed control is easy because calculation of robot dynamics including friction is not required. Experimental results verify high‐accuracy trajectory tracking of industrial robot manipulators.

  3. High-Accuracy Tracking Using Ultrawideband Signals for Enhanced Safety of Cyclists

    Directory of Open Access Journals (Sweden)

    Davide Dardari

    2017-01-01

    Full Text Available In this paper, an ultrawideband localization system to improve the cyclists’ safety is presented. The architectural solutions proposed consist of tags placed on bikes, whose positions have to be estimated, and anchors, acting as reference nodes, located at intersections and/or on vehicles. The peculiarities of the localization system in terms of accuracy and cost enable its adoption with enhanced risk assessment units situated on the infrastructure/vehicle, depending on the architecture chosen, as well as real-time warning to the road users. Experimental results reveal that the localization error, in both static and dynamic conditions, is below 50 cm in most of the cases.

  4. Affine-Invariant Geometric Constraints-Based High Accuracy Simultaneous Localization and Mapping

    Directory of Open Access Journals (Sweden)

    Gangchen Hua

    2017-01-01

    Full Text Available In this study we describe a new appearance-based loop-closure detection method for online incremental simultaneous localization and mapping (SLAM using affine-invariant-based geometric constraints. Unlike other pure bag-of-words-based approaches, our proposed method uses geometric constraints as a supplement to improve accuracy. By establishing an affine-invariant hypothesis, the proposed method excludes incorrect visual words and calculates the dispersion of correctly matched visual words to improve the accuracy of the likelihood calculation. In addition, camera’s intrinsic parameters and distortion coefficients are adequate for this method. 3D measuring is not necessary. We use the mechanism of Long-Term Memory and Working Memory (WM to manage the memory. Only a limited size of the WM is used for loop-closure detection; therefore the proposed method is suitable for large-scale real-time SLAM. We tested our method using the CityCenter and Lip6Indoor datasets. Our proposed method results can effectively correct the typical false-positive localization of previous methods, thus gaining better recall ratios and better precision.

  5. High-accuracy 3-D modeling of cultural heritage: the digitizing of Donatello's "Maddalena".

    Science.gov (United States)

    Guidi, Gabriele; Beraldin, J Angelo; Atzeni, Carlo

    2004-03-01

    Three-dimensional digital modeling of Heritage works of art through optical scanners, has been demonstrated in recent years with results of exceptional interest. However, the routine application of three-dimensional (3-D) modeling to Heritage conservation still requires the systematic investigation of a number of technical problems. In this paper, the acquisition process of the 3-D digital model of the Maddalena by Donatello, a wooden statue representing one of the major masterpieces of the Italian Renaissance which was swept away by the Florence flood of 1966 and successively restored, is described. The paper reports all the steps of the acquisition procedure, from the project planning to the solution of the various problems due to range camera calibration and to material non optically cooperative. Since the scientific focus is centered on the 3-D model overall dimensional accuracy, a methodology for its quality control is described. Such control has demonstrated how, in some situations, the ICP-based alignment can lead to incorrect results. To circumvent this difficulty we propose an alignment technique based on the fusion of ICP with close-range digital photogrammetry and a non-invasive procedure in order to generate a final accurate model. In the end detailed results are presented, demonstrating the improvement of the final model, and how the proposed sensor fusion ensure a pre-specified level of accuracy.

  6. Axis-Exchanged Compensation and Gait Parameters Analysis for High Accuracy Indoor Pedestrian Dead Reckoning

    Directory of Open Access Journals (Sweden)

    Honghui Zhang

    2015-01-01

    Full Text Available Pedestrian dead reckoning (PDR is an effective way for navigation coupled with GNSS (Global Navigation Satellite System or weak GNSS signal environment like indoor scenario. However, indoor location with an accuracy of 1 to 2 meters determined by PDR based on MEMS-IMU is still very challenging. For one thing, heading estimation is an important problem in PDR because of the singularities. For another thing, walking distance estimation is also a critical problem for pedestrian walking with randomness. Based on the above two problems, this paper proposed axis-exchanged compensation and gait parameters analysis algorithm to improve the navigation accuracy. In detail, an axis-exchanged compensation factored quaternion algorithm is put forward first to overcome the singularities in heading estimation without increasing the amount of computation. Besides, real-time heading is updated by R-adaptive Kalman filter. Moreover, gait parameters analysis algorithm can be divided into two steps: cadence detection and step length estimation. Thus, a method of cadence classification and interval symmetry is proposed to detect the cadence accurately. Furthermore, a step length model adjusted by cadence is established for step length estimation. Compared to the traditional PDR navigation, experimental results showed that the error of navigation reduces 32.6%.

  7. High accuracy microwave frequency measurement based on single-drive dual-parallel Mach-Zehnder modulator

    DEFF Research Database (Denmark)

    Zhao, Ying; Pang, Xiaodan; Deng, Lei

    2011-01-01

    A novel approach for broadband microwave frequency measurement by employing a single-drive dual-parallel Mach-Zehnder modulator is proposed and experimentally demonstrated. Based on bias manipulations of the modulator, conventional frequency-to-power mapping technique is developed by performing a...... 10−3 relative error. This high accuracy frequency measurement technique is a promising candidate for high-speed electronic warfare and defense applications.......A novel approach for broadband microwave frequency measurement by employing a single-drive dual-parallel Mach-Zehnder modulator is proposed and experimentally demonstrated. Based on bias manipulations of the modulator, conventional frequency-to-power mapping technique is developed by performing...... a two-stage frequency measurement cooperating with digital signal processing. In the experiment, 10GHz measurement range is guaranteed and the average uncertainty of estimated microwave frequency is 5.4MHz, which verifies the measurement accuracy is significantly improved by achieving an unprecedented...

  8. Brief Report: Face Configuration Accuracy and Processing Speed Among Adults with High-Functioning Autism Spectrum Disorders

    OpenAIRE

    Faja, Susan; Webb, Sara Jane; Merkle, Kristen; Aylward, Elizabeth; Dawson, Geraldine

    2008-01-01

    The present study investigates the accuracy and speed of face processing employed by high-functioning adults with autism spectrum disorders (ASDs). Two behavioral experiments measured sensitivity to distances between features and face recognition when performance depended on holistic versus featural information. Results suggest adults with ASD were less accurate, but responded as quickly as controls for both tasks. In contrast to previous findings with children, adults with ASD demonstrated a...

  9. The Effect of Moderate and High-Intensity Fatigue on Groundstroke Accuracy in Expert and Non-Expert Tennis Players

    OpenAIRE

    Mark Lyons; Yahya Al-Nakeeb; Joanne Hankey; Alan Nevill

    2013-01-01

    peer-reviewed Exploring the effects of fatigue on skilled performance in tennis presents a significant challenge to the researcher with respect to ecological validity. This study examined the effects of moderate and high-intensity fatigue on groundstroke accuracy in expert and non-expert tennis players. The research also explored whether the effects of fatigue are the same regardless of gender and player's achievement motivation characteristics. 13 expert (7 male, 6 female) and 17 non-expe...

  10. A High Accuracy Pedestrian Detection System Combining a Cascade AdaBoost Detector and Random Vector Functional-Link Net

    OpenAIRE

    Zhihui Wang; Sook Yoon; Shan Juan Xie; Yu Lu; Dong Sun Park

    2014-01-01

    In pedestrian detection methods, their high accuracy detection rates are always obtained at the cost of a large amount of false pedestrians. In order to overcome this problem, the authors propose an accurate pedestrian detection system based on two machine learning methods: cascade AdaBoost detector and random vector functional-link net. During the offline training phase, the parameters of a cascade AdaBoost detector and random vector functional-link net are trained by standard dataset. These...

  11. Towards a magnetic field stabilization at ISOLTRAP for high-accuracy mass measurements on exotic nuclides

    CERN Document Server

    Marie-Jeanne, M; Blaum, K; Djekic, S; Dworschak, M; Hager, U; Herlert, A; Nagy, S; Savreux, R; Schweikhard, L; Stahl, S; Yazidjian, C

    2008-01-01

    The field stability of a mass spectrometer plays a crucial role in the accuracy of mass measurements. In the case of mass determination of short-lived nuclides with a Penning trap, major causes of fluctuations are temperature variations in the vicinity of the trap and pressure changes in the liquid helium cryostat of the superconducting magnet. Thus systems for the temperature and pressure stabilization of the Penning trap mass spectrometer ISOLTRAP at the ISOLDE facility at CERN have been installed. A reduction of the temperature and pressure fluctuations by at least an order of magnitude down to and has been achieved, which corresponds to a relative magnetic field change of ΔB/B=2.7×10-9 and 1.1×10-10, respectively.

  12. High accuracy calculation of the hydrogen negative ion in strong magnetic fields

    Institute of Scientific and Technical Information of China (English)

    Zhao Ji-Jun; Wang Xiao-Feng; Qiao Hao-Xue

    2011-01-01

    Using a full configuration-interaction method with Hylleraas-Gaussian basis function, this paper investigates the 110+, 11(-1)+ and l1(-2)+ states of the hydrogen negative ion in strong magnetic fields. The total energies, electron detachment energies and derivatives of the total energy with respect to the magnetic field are presented as functions of magnetic field over a wide range of field strengths. Compared with the available theoretical data, the accuracy for the energies is enhanced significantly. The field regimes 3 <γ< 4 and 0.02 < 7< 0.05, in which the l1(-l)+ and l1(-2)+states start to become bound, respectively, are also determined based on the calculated electron detachment energies.

  13. Hyperbolic Method for Dispersive PDEs: Same High-Order of Accuracy for Solution, Gradient, and Hessian

    Science.gov (United States)

    Mazaheri, Alireza; Ricchiuto, Mario; Nishikawa, Hiroaki

    2016-01-01

    In this paper, we introduce a new hyperbolic first-order system for general dispersive partial differential equations (PDEs). We then extend the proposed system to general advection-diffusion-dispersion PDEs. We apply the fourth-order RD scheme of Ref. 1 to the proposed hyperbolic system, and solve time-dependent dispersive equations, including the classical two-soliton KdV and a dispersive shock case. We demonstrate that the predicted results, including the gradient and Hessian (second derivative), are in a very good agreement with the exact solutions. We then show that the RD scheme applied to the proposed system accurately captures dispersive shocks without numerical oscillations. We also verify that the solution, gradient and Hessian are predicted with equal order of accuracy.

  14. Evaluation of Heart Rate Assessment Timing, Communication, Accuracy, and Clinical Decision-Making during High Fidelity Simulation of Neonatal Resuscitation

    Directory of Open Access Journals (Sweden)

    Win Boon

    2014-01-01

    Full Text Available Objective. Accurate heart rate (HR determination during neonatal resuscitation (NR informs subsequent NR actions. This study’s objective was to evaluate HR determination timeliness, communication, and accuracy during high fidelity NR simulations that house officers completed during neonatal intensive care unit (NICU rotations. Methods. In 2010, house officers in NICU rotations completed high fidelity NR simulation. We reviewed 80 house officers’ videotaped performance on their initial high fidelity simulation session, prior to training and performance debriefing. We calculated the proportion of cases congruent with NR guidelines, using chi square analysis to evaluate performance across HR ranges relevant to NR decision-making: <60, 60–99, and ≥100 beats per minute (bpm. Results. 87% used umbilical cord palpation, 57% initiated HR assessment within 30 seconds, 70% were accurate, and 74% were communicated appropriately. HR determination accuracy varied significantly across HR ranges, with 87%, 57%, and 68% for HR <60, 60–99, and ≥100 bpm, respectively (P<0.001. Conclusions. Timeliness, communication, and accuracy of house officers’ HR determination are suboptimal, particularly for HR 60–100 bpm, which might lead to inappropriate decision-making and NR care. Training implications include emphasizing more accurate HR determination methods, better communication, and improved HR interpretation during NR.

  15. High-accuracy CFD prediction methods for fluid and structure temperature fluctuations at T-junction for thermal fatigue evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Qian, Shaoxiang, E-mail: qian.shaoxiang@jgc.com [EN Technology Center, Process Technology Division, JGC Corporation, 2-3-1 Minato Mirai, Nishi-ku, Yokohama 220-6001 (Japan); Kanamaru, Shinichiro [EN Technology Center, Process Technology Division, JGC Corporation, 2-3-1 Minato Mirai, Nishi-ku, Yokohama 220-6001 (Japan); Kasahara, Naoto [Nuclear Engineering and Management, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan)

    2015-07-15

    Highlights: • Numerical methods for accurate prediction of thermal loading were proposed. • Predicted fluid temperature fluctuation (FTF) intensity is close to the experiment. • Predicted structure temperature fluctuation (STF) range is close to the experiment. • Predicted peak frequencies of FTF and STF also agree well with the experiment. • CFD results show the proposed numerical methods are of sufficiently high accuracy. - Abstract: Temperature fluctuations generated by the mixing of hot and cold fluids at a T-junction, which is widely used in nuclear power and process plants, can cause thermal fatigue failure. The conventional methods for evaluating thermal fatigue tend to provide insufficient accuracy, because they were developed based on limited experimental data and a simplified one-dimensional finite element analysis (FEA). CFD/FEA coupling analysis is expected as a useful tool for the more accurate evaluation of thermal fatigue. The present paper aims to verify the accuracy of proposed numerical methods of simulating fluid and structure temperature fluctuations at a T-junction for thermal fatigue evaluation. The dynamic Smagorinsky model (DSM) is used for large eddy simulation (LES) sub-grid scale (SGS) turbulence model, and a hybrid scheme (HS) is adopted for the calculation of convective terms in the governing equations. Also, heat transfer between fluid and structure is calculated directly through thermal conduction by creating a mesh with near wall resolution (NWR) by allocating grid points within the thermal boundary sub-layer. The simulation results show that the distribution of fluid temperature fluctuation intensity and the range of structure temperature fluctuation are remarkably close to the experimental results. Moreover, the peak frequencies of power spectrum density (PSD) of both fluid and structure temperature fluctuations also agree well with the experimental results. Therefore, the numerical methods used in the present paper are

  16. Radiometric inter-sensor cross-calibration uncertainty using a traceable high accuracy reference hyperspectral imager

    Science.gov (United States)

    Gorroño, Javier; Banks, Andrew C.; Fox, Nigel P.; Underwood, Craig

    2017-08-01

    Optical earth observation (EO) satellite sensors generally suffer from drifts and biases relative to their pre-launch calibration, caused by launch and/or time in the space environment. This places a severe limitation on the fundamental reliability and accuracy that can be assigned to satellite derived information, and is particularly critical for long time base studies for climate change and enabling interoperability and Analysis Ready Data. The proposed TRUTHS (Traceable Radiometry Underpinning Terrestrial and Helio-Studies) mission is explicitly designed to address this issue through re-calibrating itself directly to a primary standard of the international system of units (SI) in-orbit and then through the extension of this SI-traceability to other sensors through in-flight cross-calibration using a selection of Committee on Earth Observation Satellites (CEOS) recommended test sites. Where the characteristics of the sensor under test allows, this will result in a significant improvement in accuracy. This paper describes a set of tools, algorithms and methodologies that have been developed and used in order to estimate the radiometric uncertainty achievable for an indicative target sensor through in-flight cross-calibration using a well-calibrated hyperspectral SI-traceable reference sensor with observational characteristics such as TRUTHS. In this study, Multi-Spectral Imager (MSI) of Sentinel-2 and Landsat-8 Operational Land Imager (OLI) is evaluated as an example, however the analysis is readily translatable to larger-footprint sensors such as Sentinel-3 Ocean and Land Colour Instrument (OLCI) and Visible Infrared Imaging Radiometer Suite (VIIRS). This study considers the criticality of the instrumental and observational characteristics on pixel level reflectance factors, within a defined spatial region of interest (ROI) within the target site. It quantifies the main uncertainty contributors in the spectral, spatial, and temporal domains. The resultant tool

  17. Adaptive switching frequency buck DC—DC converter with high-accuracy on-chip current sensor

    Science.gov (United States)

    Jinguang, Jiang; Fei, Huang; Zhihui, Xiong

    2015-05-01

    A current-mode PWM buck DC—DC converter is proposed. With the high-accuracy on-chip current sensor, the switching frequency can be selected automatically according to load requirements. This method improves efficiency and obtains an excellent transient response. The high accuracy of the current sensor is achieved by a simple switch technique without an amplifier. This has the direct benefit of reducing power dissipation and die size. Additionally, a novel soft-start circuit is presented to avoid the inrush current at the starting up state. Finally, this DC—DC converter is fabricated with the 0.5 μm standard CMOS process. The chip occupies 3.38 mm2. The accuracy of the proposed current sensor can achieve 99.5% @ 200 mA. Experimental results show that the peak efficiency is 91.8%. The input voltage ranges from 5 to 18 V, while a 2 A load current can be obtained. Project supported by the National Natural Science Foundation of China (No. 41274047), the Natural Science Foundation of Jiangsu Province (No. BK2012639), the Science and Technology Enterprises in Jiangsu Province Technology Innovation Fund (No. BC2012121), and the Changzhou Science and Technology Support (Industrial) Project (No. CE20120074).

  18. High Accuracy Passive Magnetic Field-Based Localization for Feedback Control Using Principal Component Analysis

    Directory of Open Access Journals (Sweden)

    Shaohui Foong

    2016-08-01

    Full Text Available In this paper, a novel magnetic field-based sensing system employing statistically optimized concurrent multiple sensor outputs for precise field-position association and localization is presented. This method capitalizes on the independence between simultaneous spatial field measurements at multiple locations to induce unique correspondences between field and position. This single-source-multi-sensor configuration is able to achieve accurate and precise localization and tracking of translational motion without contact over large travel distances for feedback control. Principal component analysis (PCA is used as a pseudo-linear filter to optimally reduce the dimensions of the multi-sensor output space for computationally efficient field-position mapping with artificial neural networks (ANNs. Numerical simulations are employed to investigate the effects of geometric parameters and Gaussian noise corruption on PCA assisted ANN mapping performance. Using a 9-sensor network, the sensing accuracy and closed-loop tracking performance of the proposed optimal field-based sensing system is experimentally evaluated on a linear actuator with a significantly more expensive optical encoder as a comparison.

  19. High-resolution CT of transplanted teeth: imaging technique and measurement accuracy

    Energy Technology Data Exchange (ETDEWEB)

    Gahleitner, Andre [Medical University of Vienna, Department of Radiology/Osteology and MR, Vienna (Austria); Medical University Vienna, Department of Radiology, Vienna (Austria); Kuchler, Ulrike; Heschl, Janina; Watzek, Georg [Medical University of Vienna, Department of Oral Surgery, Vienna (Austria); Homolka, Peter [Medical University of Vienna, Center for Biomedical Engineering and Physics, Vienna (Austria); Imhof, Herwig [Medical University of Vienna, Department of Radiology/Osteology and MR, Vienna (Austria)

    2008-12-15

    The aim of this study was to determine the accuracy of crown diameter measurements by dental CT as a tool for preoperative diagnosis before tooth transplantations. Fifty-eight patients underwent clinically indicated dental CT. The diameter of the crowns were measured by CT using a standard protocol (1.5-mm slice thickness, 1-mm table feed, 120 kV, 25-75 mA/s, 2-s scan time/slice, 512 matrix) and a standard dental software package. Postoperatively, the same distances were clinically measured using a sliding gauge. The degree of the deviation between CT measurements and clinical measurements was in the sub-millimeter range. According to the regression analysis, the correlation coefficient equals 0.98 and 0.97, indicating a strong relationship between the CT and the manual measurement of the crown diameter in the bucco-lingual and the mesio-distal direction. The mean deviation of CT measurements with regard to the bucco-lingual diameter of the crown was +0.08 mm (SD: {+-}0.38 mm). For the mesio-distal diameter, the mean deviation of CT measurements was -0.24 mm (SD: {+-}0.53 mm). These results demonstrate that dental CT promises to be a valuable tool for the evaluation of the potential and optimal size and site for tooth transplantations. (orig.)

  20. Novel speech signal processing algorithms for high-accuracy classification of Parkinson's disease.

    Science.gov (United States)

    Tsanas, Athanasios; Little, Max A; McSharry, Patrick E; Spielman, Jennifer; Ramig, Lorraine O

    2012-05-01

    There has been considerable recent research into the connection between Parkinson's disease (PD) and speech impairment. Recently, a wide range of speech signal processing algorithms (dysphonia measures) aiming to predict PD symptom severity using speech signals have been introduced. In this paper, we test how accurately these novel algorithms can be used to discriminate PD subjects from healthy controls. In total, we compute 132 dysphonia measures from sustained vowels. Then, we select four parsimonious subsets of these dysphonia measures using four feature selection algorithms, and map these feature subsets to a binary classification response using two statistical classifiers: random forests and support vector machines. We use an existing database consisting of 263 samples from 43 subjects, and demonstrate that these new dysphonia measures can outperform state-of-the-art results, reaching almost 99% overall classification accuracy using only ten dysphonia features. We find that some of the recently proposed dysphonia measures complement existing algorithms in maximizing the ability of the classifiers to discriminate healthy controls from PD subjects. We see these results as an important step toward noninvasive diagnostic decision support in PD.

  1. High Accuracy Passive Magnetic Field-Based Localization for Feedback Control Using Principal Component Analysis

    Science.gov (United States)

    Foong, Shaohui; Sun, Zhenglong

    2016-01-01

    In this paper, a novel magnetic field-based sensing system employing statistically optimized concurrent multiple sensor outputs for precise field-position association and localization is presented. This method capitalizes on the independence between simultaneous spatial field measurements at multiple locations to induce unique correspondences between field and position. This single-source-multi-sensor configuration is able to achieve accurate and precise localization and tracking of translational motion without contact over large travel distances for feedback control. Principal component analysis (PCA) is used as a pseudo-linear filter to optimally reduce the dimensions of the multi-sensor output space for computationally efficient field-position mapping with artificial neural networks (ANNs). Numerical simulations are employed to investigate the effects of geometric parameters and Gaussian noise corruption on PCA assisted ANN mapping performance. Using a 9-sensor network, the sensing accuracy and closed-loop tracking performance of the proposed optimal field-based sensing system is experimentally evaluated on a linear actuator with a significantly more expensive optical encoder as a comparison. PMID:27529253

  2. Designing a high accuracy 3D auto stereoscopic eye tracking display, using a common LCD monitor

    Science.gov (United States)

    Taherkhani, Reza; Kia, Mohammad

    2012-09-01

    This paper describes the design and building of a low cost and practical stereoscopic display that does not need to wear special glasses, and uses eye tracking to give a large degree of freedom to viewer (or viewer's) movement while displaying the minimum amount of information. The parallax barrier technique is employed to turn a LCD into an auto-stereoscopic display. The stereo image pair is screened on the usual liquid crystal display simultaneously but in different columns of pixels. Controlling of the display in red-green-blue sub pixels increases the accuracy of light projecting direction to less than 2 degrees without losing too much LCD's resolution and an eye-tracking system determines the correct angle to project the images along the viewer's eye pupils and an image processing system puts the 3D images data in correct R-G-B sub pixels. 1.6 degree of light direction controlling achieved in practice. The 3D monitor is just made by applying some simple optical materials on a usual LCD display with normal resolution. [Figure not available: see fulltext.

  3. High Accuracy Passive Magnetic Field-Based Localization for Feedback Control Using Principal Component Analysis.

    Science.gov (United States)

    Foong, Shaohui; Sun, Zhenglong

    2016-08-12

    In this paper, a novel magnetic field-based sensing system employing statistically optimized concurrent multiple sensor outputs for precise field-position association and localization is presented. This method capitalizes on the independence between simultaneous spatial field measurements at multiple locations to induce unique correspondences between field and position. This single-source-multi-sensor configuration is able to achieve accurate and precise localization and tracking of translational motion without contact over large travel distances for feedback control. Principal component analysis (PCA) is used as a pseudo-linear filter to optimally reduce the dimensions of the multi-sensor output space for computationally efficient field-position mapping with artificial neural networks (ANNs). Numerical simulations are employed to investigate the effects of geometric parameters and Gaussian noise corruption on PCA assisted ANN mapping performance. Using a 9-sensor network, the sensing accuracy and closed-loop tracking performance of the proposed optimal field-based sensing system is experimentally evaluated on a linear actuator with a significantly more expensive optical encoder as a comparison.

  4. ISPA - a high accuracy X-ray and gamma camera Exhibition LEPFest 2000

    CERN Multimedia

    2000-01-01

    ISPA offers ... Ten times better resolution than Anger cameras High efficiency single gamma counting Noise reduction by sensitivity to gamma energy ...for Single Photon Emission Computed Tomography (SPECT)

  5. Expression of CRM1 and CDK5 shows high prognostic accuracy for gastric cancer

    Science.gov (United States)

    Sun, Yu-Qin; Xie, Jian-Wei; Xie, Hong-Teng; Chen, Peng-Chen; Zhang, Xiu-Li; Zheng, Chao-Hui; Li, Ping; Wang, Jia-Bin; Lin, Jian-Xian; Cao, Long-Long; Huang, Chang-Ming; Lin, Yao

    2017-01-01

    AIM To evaluate the predictive value of the expression of chromosomal maintenance (CRM)1 and cyclin-dependent kinase (CDK)5 in gastric cancer (GC) patients after gastrectomy. METHODS A total of 240 GC patients who received standard gastrectomy were enrolled in the study. The expression level of CRM1 and CDK5 was detected by immunohistochemistry. The correlations between CRM1 and CDK5 expression and clinicopathological factors were explored. Univariate and multivariate survival analyses were used to identify prognostic factors for GC. Receiver operating characteristic analysis was used to compare the accuracy of the prediction of clinical outcome by the parameters. RESULTS The expression of CRM1 was significantly related to size of primary tumor (P = 0.005), Borrmann type (P = 0.006), degree of differentiation (P = 0.004), depth of invasion (P = 0.008), lymph node metastasis (P = 0.013), TNM stage (P = 0.002) and distant metastasis (P = 0.015). The expression of CDK5 was significantly related to sex (P = 0.048) and Lauren’s classification (P = 0.011). Multivariate Cox regression analysis identified that CRM1 and CDK5 co-expression status was an independent prognostic factor for overall survival (OS) of patients with GC. Integration of CRM1 and CDK5 expression could provide additional prognostic value for OS compared with CRM1 or CDK5 expression alone (P = 0.001). CONCLUSION CRM1 and CDK5 co-expression was an independent prognostic factors for GC. Combined CRM1 and CDK5 expression could provide a prognostic model for OS of GC. PMID:28373767

  6. Influence of measuring algorithm on shape accuracy in the compensating turning of high gradient thin-wall parts

    Science.gov (United States)

    Wang, Tao; Wang, Guilin; Zhu, Dengchao; Li, Shengyi

    2015-02-01

    In order to meet the requirement of aerodynamics, the infrared domes or windows with conformal and thin-wall structure becomes the development trend of high-speed aircrafts in the future. But these parts usually have low stiffness, the cutting force will change along with the axial position, and it is very difficult to meet the requirement of shape accuracy by single machining. Therefore, on-machine measurement and compensating turning are used to control the shape errors caused by the fluctuation of cutting force and the change of stiffness. In this paper, on the basis of ultra precision diamond lathe, a contact measuring system with five DOFs is developed to achieve on-machine measurement of conformal thin-wall parts with high accuracy. According to high gradient surface, the optimizing algorithm is designed on the distribution of measuring points by using the data screening method. The influence rule of sampling frequency is analyzed on measuring errors, the best sampling frequency is found out based on planning algorithm, the effect of environmental factors and the fitting errors are controlled within lower range, and the measuring accuracy of conformal dome is greatly improved in the process of on-machine measurement. According to MgF2 conformal dome with high gradient, the compensating turning is implemented by using the designed on-machine measuring algorithm. The shape error is less than PV 0.8μm, greatly superior compared with PV 3μm before compensating turning, which verifies the correctness of measuring algorithm.

  7. High-accuracy measurement of ship velocities by DGPS; DGPS ni yoru sensoku keisoku no koseidoka ni tsuite

    Energy Technology Data Exchange (ETDEWEB)

    Yamaguchi, S.; Koterayama, W. [Kyushu Univ., Fukuoka (Japan). Research Inst. for Applied Mechanics

    1996-04-10

    The differential global positioning system (DGPS) can eliminate most of errors in ship velocity measurement by GPS positioning alone. Through two rounds of marine observations by towing an observation robot in summer 1995, the authors attempted high-accuracy measurement of ship velocities by DGPS, and also carried out both positioning by GPS alone and measurement using the bottom track of ADCP (acoustic Doppler current profiler). In this paper, the results obtained by these measurement methods were examined through comparison among them, and the accuracy of the measured ship velocities was considered. In DGPS measurement, both translocation method and interference positioning method were used. ADCP mounted on the observation robot allowed measurement of the velocity of current meter itself by its bottom track in shallow sea areas less than 350m. As the result of these marine observations, it was confirmed that the accuracy equivalent to that of direct measurement by bottom track is possible to be obtained by DGPS. 3 refs., 5 figs., 1 tab.

  8. High-accuracy current generation in the nanoampere regime from a silicon single-trap electron pump

    Science.gov (United States)

    Yamahata, Gento; Giblin, Stephen P.; Kataoka, Masaya; Karasawa, Takeshi; Fujiwara, Akira

    2017-01-01

    A gigahertz single-electron (SE) pump with a semiconductor charge island is promising for a future quantum current standard. However, high-accuracy current in the nanoampere regime is still difficult to achieve because the performance of SE pumps tends to degrade significantly at frequencies exceeding 1 GHz. Here, we demonstrate robust SE pumping via a single-trap level in silicon up to 7.4 GHz, at which the pumping current exceeds 1 nA. An accuracy test with an uncertainty of about one part per million (ppm) reveals that the pumping current deviates from the ideal value by only about 20 ppm at the flattest part of the current plateau. This value is two orders of magnitude better than the best one reported in the nanoampere regime. In addition, the pumping accuracy is almost unchanged up to 7.4 GHz, probably due to strong electron confinement in the trap. These results indicate that trap-mediated SE pumping is promising for achieving the practical operation of the quantum current standard. PMID:28322339

  9. DURA-Peel, DURACON-Based Removable High Accuracy IR Thermography Coatings Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Fiber reinforced composite materials are used extensively in aerospace applications due to their high stiffness and strength to weight ratio, and superior thermal,...

  10. Interethnic differences in the accuracy of anthropometric indicators of obesity in screening for high risk of coronary heart disease

    Science.gov (United States)

    Herrera, VM; Casas, JP; Miranda, JJ; Perel, P; Pichardo, R; González, A; Sanchez, JR; Ferreccio, C; Aguilera, X; Silva, E; Oróstegui, M; Gómez, LF; Chirinos, JA; Medina-Lezama, J; Pérez, CM; Suárez, E; Ortiz, AP; Rosero, L; Schapochnik, N; Ortiz, Z; Ferrante, D; Diaz, M; Bautista, LE

    2009-01-01

    Background Cut points for defining obesity have been derived from mortality data among Whites from Europe and the United States and their accuracy to screen for high risk of coronary heart disease (CHD) in other ethnic groups has been questioned. Objective To compare the accuracy and to define ethnic and gender-specific optimal cut points for body mass index (BMI), waist circumference (WC) and waist-to-hip ratio (WHR) when they are used in screening for high risk of CHD in the Latin-American and the US populations. Methods We estimated the accuracy and optimal cut points for BMI, WC and WHR to screen for CHD risk in Latin Americans (n=18 976), non-Hispanic Whites (Whites; n=8956), non-Hispanic Blacks (Blacks; n=5205) and Hispanics (n=5803). High risk of CHD was defined as a 10-year risk ≥20% (Framingham equation). The area under the receiver operator characteristic curve (AUC) and the misclassification-cost term were used to assess accuracy and to identify optimal cut points. Results WHR had the highest AUC in all ethnic groups (from 0.75 to 0.82) and BMI had the lowest (from 0.50 to 0.59). Optimal cut point for BMI was similar across ethnic/gender groups (27 kg/m2). In women, cut points for WC (94 cm) and WHR (0.91) were consistent by ethnicity. In men, cut points for WC and WHR varied significantly with ethnicity: from 91 cm in Latin Americans to 102 cm in Whites, and from 0.94 in Latin Americans to 0.99 in Hispanics, respectively. Conclusion WHR is the most accurate anthropometric indicator to screen for high risk of CHD, whereas BMI is almost uninformative. The same BMI cut point should be used in all men and women. Unique cut points for WC and WHR should be used in all women, but ethnic-specific cut points seem warranted among men. PMID:19238159

  11. High Accuracy Investigation of Microwave Absorption in Polymer Electrical Components on Motherboard of Computers

    Science.gov (United States)

    Dašić, P.; Hutanu, C.; Jevremović, V.; Dobra, R.; Risteiu, M.; Ileana, I.

    2017-06-01

    Electronic operating at high frequencies can have problems with emission of high frequency noise. Once put inside an enclosure, the energy will add in phase at certain frequencies to cause resonances which will hinder the performance of the device. These absorbers are based upon open celled foam impregnated with a carbon coating. It is quite possible that in the near future, microprocessors would be to work on a frequency located in 5 to 10 GHz. In these circumstances it is useful to know how and how much of the electromagnetic field emitted by a microprocessor, it is absorbed by the circuit elements in the immediate vicinity of the microprocessor. The aim of this contribution is to demonstrate throughout high-level experimental analysis how the main electric parameters of polymer materials, which build the printed circuits and the one of electric capacitors and resistors, depend on the frequencies on which they work from the microwave range.

  12. Bayesian approach increases accuracy when selecting cowpea genotypes with high adaptability and phenotypic stability.

    Science.gov (United States)

    Barroso, L M A; Teodoro, P E; Nascimento, M; Torres, F E; Dos Santos, A; Corrêa, A M; Sagrilo, E; Corrêa, C C G; Silva, F A; Ceccon, G

    2016-03-11

    This study aimed to verify that a Bayesian approach could be used for the selection of upright cowpea genotypes with high adaptability and phenotypic stability, and the study also evaluated the efficiency of using informative and minimally informative a priori distributions. Six trials were conducted in randomized blocks, and the grain yield of 17 upright cowpea genotypes was assessed. To represent the minimally informative a priori distributions, a probability distribution with high variance was used, and a meta-analysis concept was adopted to represent the informative a priori distributions. Bayes factors were used to conduct comparisons between the a priori distributions. The Bayesian approach was effective for selection of upright cowpea genotypes with high adaptability and phenotypic stability using the Eberhart and Russell method. Bayes factors indicated that the use of informative a priori distributions provided more accurate results than minimally informative a priori distributions.

  13. Mode-resolved frequency comb interferometry for high-accuracy long distance measurement

    NARCIS (Netherlands)

    Van den Berg, S.A.; Van Eldik, S.; Bhattacharya, N.

    2015-01-01

    Optical frequency combs have developed into powerful tools for distance metrology. In this paper we demonstrate absolute long distance measurement using a single femtosecond frequency comb laser as a multi-wavelength source. By applying a high-resolution spectrometer based on a virtually imaged phas

  14. Novel method of high-accuracy wavefront-phase and amplitude correction for coronagraphy

    Science.gov (United States)

    Bowers, Charles W.; Woodgate, Bruce E.; Lyon, Richard G.

    2003-11-01

    Detection of extra-solar, and especially terrestrial-like planets, using coronagraphy requires an extremely high level of wavefront correction. For example, the study of Woodruff et al. (2002) has shown that phase uniformity of order 10-4λ(rms) must be achieved over the critical range of spatial frequencies to produce the ~1010 contrast needed for the Terrestrial Planet Finder (TPF) mission. Correction of wavefront phase errors to this level may be accomplished by using a very high precision deformable mirror (DM). However, not only phase but also amplitude uniformity of the same scale (~10-4) and over the same spatial frequency range must be simultaneously obtained to remove all residual speckle in the image plane. We present a design for producing simultaneous wavefront phase and amplitude uniformity to high levels from an input wavefront of lower quality. The design uses a dual Michelson interferometer arrangement incorporating two DM and a single, fixed mirror (all at pupils) and two beamsplitters: one with unequal (asymmetric) beam splitting and one with symmetric beam splitting. This design allows high precision correction of both phase and amplitude using DM with relatively coarse steps and permits a simple correction algorithm.

  15. High-accuracy alignment based on atmospherical dispersion - technological approaches and solutions for the dual-wavelength transmitter

    Energy Technology Data Exchange (ETDEWEB)

    Burkhard, Boeckem [Institute for Geodesy and Photogrammetry, ETH Zurich (Switzerland)

    1999-07-01

    In the course of the progressive developments of sophisticated geodetic systems utilizing electromagnetic waves in the visible or near IR-range a more detailed knowledge of the propagation medium and coevally solutions of atmospherically induced limitations will become important. An alignment system based on atmospherical dispersion, called a dispersometer, is a metrological solution to the atmospherically induced limitations, in optical alignment and direction observations of high accuracy. In the dispersometer we are using the dual-wavelength method for dispersive air to obtain refraction compensated angle measurements, the detrimental impact of atmospheric turbulence notwithstanding. The principle of the dual-wavelength method utilizes atmospherical dispersion, i.e. the wavelength dependence of the refractive index. The difference angle between two light beams of different wavelengths, which is called the dispersion angle {delta}{beta}, is to first approximation proportional to the refraction angle: {beta}{sub IR} {nu}({beta}{sub blue} - {beta}{sub IR}) = {nu} {delta}{beta}, this equation implies that the dispersion angle has to be measured at least 42 times more accurate than the desired accuracy of the refraction angle for the wavelengths used in the present dispersometer. This required accuracy constitutes one major difficulty for the instrumental performance in applying the dispersion effect. However, the dual-wavelength method can only be successfully used in an optimized transmitter-receiver combination. Beyond the above mentioned resolution requirement for the detector, major difficulties in instrumental realization arise in the availability of a suitable dual-wavelength laser light source, laser light modulation with a very high extinction ratio and coaxial emittance of mono-mode radiation at both wavelengths. Therefore, this paper focuses on the solutions of the dual-wavelength transmitter introducing a new hardware approach and a complete re-design of

  16. High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast

    DEFF Research Database (Denmark)

    Gnad, Florian; de Godoy, Lyris M F; Cox, Jürgen

    2009-01-01

    mapped to 1118 proteins, representatively covering the yeast kinome and a multitude of transcription factors. We show that a single false discovery rate for all peptide identifications significantly overestimates occurrence of rare modifications, such as tyrosine phosphorylation in yeast. The identified...... phosphorylation sites are predominantly located on irregularly structured and accessible protein regions. We found high evolutionary conservation of phosphorylated proteins and a large overlap of significantly over-represented motifs with the human phosphoproteome. Nevertheless, phosphorylation events at the site...... level were not highly conserved between yeast and higher eukaryotes, which points to metazoan-specific kinase and substrate families. We constructed a yeast-specific phosphorylation sites predictor on the basis of a support vector machine, which - together with the yeast phosphorylation data...

  17. High accuracy and precision micro injection moulding of thermoplastic elastomers micro ring production

    DEFF Research Database (Denmark)

    Calaon, Matteo; Tosello, Guido; Elsborg, René

    2016-01-01

    of using tool geometries as reference calibrated artefacts to establish effective process technology development and control. The results allow identifying the correct process windows for optimal part quality reducing product dimensional variation in the micrometer dimensional range. The proposed......The mass-replication nature of the process calls for fast monitoring of process parameters and product geometrical characteristics. In this direction, the present study addresses the possibility to develop a micro manufacturing platform for micro assembly injection moulding with real-time process/product...... monitoring and metrology. The study represent a new concept yet to be developed with great potential for high precision mass-manufacturing of highly functional 3D multi-material (i.e. including metal/soft polymer) micro components. The activities related to HINMICO project objectives proves the importance...

  18. Challenges in high accuracy surface replication for micro optics and micro fluidics manufacture

    DEFF Research Database (Denmark)

    Tosello, Guido; Hansen, Hans Nørgaard; Calaon, Matteo;

    2014-01-01

    by replication technologies such as nickel electroplating. All replication steps are enabled by a high precision master and high reproduction fidelity to ensure that the functionalities associated with the design are transferred to the final component. Engineered surface micro structures can be either......Patterning the surface of polymer components with microstructured geometries is employed in optical and microfluidic applications. Mass fabrication of polymer micro structured products is enabled by replication technologies such as injection moulding. Micro structured tools are also produced...... distributed, e.g., to create an optical pattern, or discretised, e.g., as micro channels for fluids manipulation. Key aspects of two process chains based on replication technologies for both types of micro structures are investigated: lateral replication fidelity, dimensional control at micro scale, edge...

  19. Modelling and Control of Stepper Motors for High Accuracy Positioning Systems Used in Radioactive Environments

    OpenAIRE

    Picatoste Ruilope, Ricardo

    2014-01-01

    Hybrid Stepper Motors are widely used in open-loop position applications. They are the choice of actuation for the collimators in the Large Hadron Collider, the largest particle accelerator at CERN. In this case the positioning requirements and the highly radioactive operating environment are unique. The latter forces both the use of long cables to connect the motors to the drives which act as transmission lines and also prevents the use of standard position sensors. However, reliable and pre...

  20. The Ultrasonic Piezo Drive an Innovative Solution for High-Accuracy Positioning

    OpenAIRE

    Seiler, René; Six, Marc; Debornot, Miguel; Le Letty, Ronan; CLAEYSSEN, Frank

    2002-01-01

    Piezo-electric motors have been successfully developed for various applications like autofocus drives in camera lenses and handling equipment for semiconductor production. Their high speed and accurate positioning capability, combined with a favourable holding torque in unpowered condition, make piezo motors also very attractive for actuation purposes in spacecraft mechanisms. However, so far only a few studies have been reported considering their suitability for actual use in space. Piezo mo...

  1. High-Accuracy Methods for Numerical Flow Analysis Using Adaptive Non-Linear Wavelets

    Science.gov (United States)

    2012-08-01

    to the research by Bacry, Mallat and Papanicolaou [10] or Holmström and Walden [11], AWGM solves PDE problems in a wavelet coefficient space. It is...of the threshold value, these variations are discarded and restricted by multiplying the weighting factor . This process can especially contribute the...weighting factor . This restriction technique enhances the convergence rate of steady state calculations. References [1] Harten A., “High

  2. High accuracy measure of atomic polarizability in an optical lattice clock

    OpenAIRE

    Sherman, J. A.; Lemke, N. D.; Hinkley, N.; Pizzocaro, M.; Fox, R. W.; Ludlow, A. D.; Oates, C. W.

    2011-01-01

    Despite being a canonical example of quantum mechanical perturbation theory, as well as one of the earliest observed spectroscopic shifts, the Stark effect contributes the largest source of uncertainty in a modern optical atomic clock through blackbody radiation. By employing an ultracold, trapped atomic ensemble and high stability optical clock, we characterize the quadratic Stark effect with unprecedented precision. We report the ytterbium optical clock's sensitivity to electric fields (suc...

  3. Two-dimensional DOA Estimation with High Accuracy for MIMO Radar Using Cross Array

    Directory of Open Access Journals (Sweden)

    Liang Hao

    2016-06-01

    Full Text Available In this study, we investigate the estimation of the Two-Dimensional (2D Direction Of Arrival (DOA in monostatic multiple-input–multiple-output radar with cross array and propose a novel, highly accurate DOA estimation method based on unitary transformation. First, we design a new unitary matrix using the central symmetry of a cross array at transmit and receive sites. Then, the rotational invariance relationships of these arrays with long and short baselines can be transformed into a real-value field via unitary transformation. In addition, non-ambiguous and highly accurate 2D DOA estimations can be obtained using a unitary dual-resolution ESPRIT algorithm. Simulations show that the proposed method can estimate 2D highly accurate spatial angles using automatic pairing without incurring the expense of array aperture and peak searching. Compared with traditional unitary transformation, the steering vectors of transmit and receive arrays can be transformed into real-value fields via the unitary matrix and the transformation method of our scheme, respectively. This effectively overcomes the problem of shift invariance factors in real-value fields that cannot be extracted using traditional algorithms. Therefore, the proposed method can absolutely compute eigenvalue decomposition and estimate parameters in a real-value field, resulting in lower computational complexity compared with traditional methods. Simulation results verify both the correctness of our theoretical analysis and the effectiveness of the proposed algorithm.

  4. Accuracy optimization of high-speed AFM measurements using Design of Experiments

    DEFF Research Database (Denmark)

    Tosello, Guido; Marinello, F.; Hansen, Hans Nørgaard

    2010-01-01

    , the estimated dimensions of measured features. The definition of scan settings is based on a comprehensive optimization that targets maximization of information from collected data and minimization of measurement uncertainty and scan time. The Design of Experiments (DOE) technique is proposed and applied......Atomic Force Microscopy (AFM) is being increasingly employed in industrial micro/nano manufacturing applications and integrated into production lines. In order to achieve reliable process and product control at high measuring speed, instrument optimization is needed. Quantitative AFM measurement...

  5. Energy-preserving numerical schemes of high accuracy for one-dimensional Hamiltonian systems

    CERN Document Server

    Cieśliński, Jan L

    2011-01-01

    We present a class of non-standard numerical schemes which are modifications of the discrete gradient method. They preserve the energy integral exactly (up to the round-off error). The considered class contains locally exact discrete gradient schemes and integrators of arbitrary high order. In numerical experiments we compare our integrators with some other numerical schemes, including the standard discrete gradient method, the leap-frog scheme and a symplectic scheme of 4th order. We study the error accumulation for very long time and the conservation of the energy integral.

  6. A three axis turntable's online initial state measurement method based on the high-accuracy laser gyro SINS

    Science.gov (United States)

    Gao, Chunfeng; Wei, Guo; Wang, Qi; Xiong, Zhenyu; Wang, Qun; Long, Xingwu

    2016-10-01

    As an indispensable equipment in inertial technology tests, the three-axis turntable is widely used in the calibration of various types inertial navigation systems (INS). In order to ensure the calibration accuracy of INS, we need to accurately measure the initial state of the turntable. However, the traditional measuring method needs a lot of exterior equipment (such as level instrument, north seeker, autocollimator, etc.), and the test processing is complex, low efficiency. Therefore, it is relatively difficult for the inertial measurement equipment manufacturers to realize the self-inspection of the turntable. Owing to the high precision attitude information provided by the laser gyro strapdown inertial navigation system (SINS) after fine alignment, we can use it as the attitude reference of initial state measurement of three-axis turntable. For the principle that the fixed rotation vector increment is not affected by measuring point, we use the laser gyro INS and the encoder of the turntable to provide the attitudes of turntable mounting plat. Through this way, the high accuracy measurement of perpendicularity error and initial attitude of the three-axis turntable has been achieved.

  7. High accuracy indirect optical manipulation of live cells with functionalized microtools

    Science.gov (United States)

    Vizsnyiczai, Gaszton; Aekbote, Badri L.; Buzás, András.; Grexa, István.; Ormos, Pál.; Kelemen, Lóránd

    2016-09-01

    Optical micro manipulation of live cells has been extensively used to study a wide range of cellular phenomena with relevance in basic research or in diagnostics. The approaches span from manipulation of many cells for high throughput measurement or sorting, to more elaborated studies of intracellular events on trapped single cells when coupled with modern imaging techniques. In case of direct cell trapping the damaging effects of light-cell interaction must be minimized, for instance with the choice of proper laser wavelength. Microbeads have already been used for trapping cells indirectly thereby reducing the irradiation damage and increasing trapping efficiency with their high refractive index contrast. We show here that such intermediate objects can be tailor-made for indirect cell trapping to further increase cell-to-focal spot distance while maintaining their free and fast maneuverability. Carefully designed structures were produced with two-photon polymerization with shapes optimized for effective manipulation and cell attachment. Functionalization of the microstructures is also presented that enables cell attachment to them within a few seconds with strength much higher that the optical forces. Fast cell actuation in 6 degrees of freedom is demonstrated with the outlook to possible applications in cell imaging.

  8. Automated high-accuracy mutation screening with the WAVE nucleic acid fragment analysis system

    Science.gov (United States)

    Hecker, Karl H.

    2002-06-01

    The analysis of DNA fragments by ion-pair reversed-phase high-performance liquid chromatography on an alkylated, nonporous poly(styrene-divinylbenzene) matrix (DNA Cartridge) using the WAVE Nucleic Acid Fragment Analysis System is a powerful and versatile tool for DNA analysis. Resolution of DNA fragments is based on two principles, size-dependent retention of double-stranded (ds) DNA and differential retention of ds vs. single-stranded (ss) DNA. Temperature Modulated Heteroduplex Analysis utilizes both principles of separation to detect single nucleotide polymorphisms (SNP) and short insertions/deletions. At a given temperature the difference in the melting between homo- and heteroduplexes is revealed by differences in retention times. The temperature at which differential melting occurs is sequence dependent and is predicated accurately using either WAVEMAKER or WAVE Navigator software, which use a modified Fixman-Friere algorithm. Detection of known and unknown sequence variations can be performed on DNA fragments of up to 1,000 base pairs with high sensitivity and specificity. The use of fluorescent labels is compatible with the technology and increases sensitivity. Retention times are increased and resolution is not affected. Fluorescent labeling significantly increases sensitivity.

  9. High-accuracy measurement of the emission spectrum of liquid xenon in the vacuum ultraviolet region

    Energy Technology Data Exchange (ETDEWEB)

    Fujii, Keiko, E-mail: fujii-keiko-nv@ynu.jp [Faculty of Engineering, Yokohama National University, Yokohama, Kanagawa 240-8501 (Japan); Endo, Yuya; Torigoe, Yui; Nakamura, Shogo [Faculty of Engineering, Yokohama National University, Yokohama, Kanagawa 240-8501 (Japan); Haruyama, Tomiyoshi; Kasami, Katsuyu [High Energy Accelerator Research Organization (KEK), Tsukuba, Ibaraki 305-0801 (Japan); Mihara, Satoshi; Saito, Kiwamu; Sasaki, Shinichi [High Energy Accelerator Research Organization (KEK), Tsukuba, Ibaraki 305-0801 (Japan); The Graduate School of Advanced Studies, Hayama, Kanagawa 240-0193 (Japan); Tawara, Hiroko [High Energy Accelerator Research Organization (KEK), Tsukuba, Ibaraki 305-0801 (Japan)

    2015-09-21

    The emission spectrum of cryogenic liquid xenon in the vacuum ultraviolet region was measured by irradiating liquid xenon with gamma-rays from a radioactive source. To achieve a high signal-to-noise ratio, we employed coincident photon counting. Additionally, the charge of the photo-sensor signals was measured to estimate the number of detected photons accurately. In addition, proper corrections were incorporated for the wavelength; response functions of the apparatus obtained using a low-pressure mercury lamp, and photon detection efficiencies of the optical system were considered. The obtained emission spectrum is found to be in the shape of a Gaussian function, with the center at 57,199±34 (stat.)±33 (syst.) cm{sup −1} (174.8±0.1 (stat.)±0.1 (syst.) nm) and the full width at half maximum of 3328±72 (stat.)±65 (syst.) cm{sup −1} (10.2±0.2 (stat.)±0.2 (sys.) nm). These results are the most accurate values obtained in terms of the data acquisition method and the calibration for the experimental system and provide valuable information regarding the high-precision instruments that employ a liquid-xenon scintillator.

  10. Modelling and Control of Stepper Motors for High Accuracy Positioning Systems Used in Radioactive Environments

    CERN Document Server

    Picatoste Ruilope, Ricardo; Masi, Alessandro

    Hybrid Stepper Motors are widely used in open-loop position applications. They are the choice of actuation for the collimators in the Large Hadron Collider, the largest particle accelerator at CERN. In this case the positioning requirements and the highly radioactive operating environment are unique. The latter forces both the use of long cables to connect the motors to the drives which act as transmission lines and also prevents the use of standard position sensors. However, reliable and precise operation of the collimators is critical for the machine, requiring the prevention of step loss in the motors and maintenance to be foreseen in case of mechanical degradation. In order to make the above possible, an approach is proposed for the application of an Extended Kalman Filter to a sensorless stepper motor drive, when the motor is separated from its drive by long cables. When the long cables and high frequency pulse width modulated control voltage signals are used together, the electrical signals difer greatl...

  11. Determination of the QCD Λ Parameter and the Accuracy of Perturbation Theory at High Energies.

    Science.gov (United States)

    Dalla Brida, Mattia; Fritzsch, Patrick; Korzec, Tomasz; Ramos, Alberto; Sint, Stefan; Sommer, Rainer

    2016-10-28

    We discuss the determination of the strong coupling α_{MS[over ¯]}(m_{Z}) or, equivalently, the QCD Λ parameter. Its determination requires the use of perturbation theory in α_{s}(μ) in some scheme s and at some energy scale μ. The higher the scale μ, the more accurate perturbation theory becomes, owing to asymptotic freedom. As one step in our computation of the Λ parameter in three-flavor QCD, we perform lattice computations in a scheme that allows us to nonperturbatively reach very high energies, corresponding to α_{s}=0.1 and below. We find that (continuum) perturbation theory is very accurate there, yielding a 3% error in the Λ parameter, while data around α_{s}≈0.2 are clearly insufficient to quote such a precision. It is important to realize that these findings are expected to be generic, as our scheme has advantageous properties regarding the applicability of perturbation theory.

  12. A magnetic bearing momentum wheel for high pointing accuracy and vibration sensitive space applications

    Science.gov (United States)

    Bichler, U. J.

    The paper describes a magnetic bearing momentum wheel (MW-X) theoretically and experimentally with attention given to its low-noise application to spacecraft attitude-control systems. The MW-X gyroscopic actuator comprises a rotor, emergency bearings, a locking mechanisms, and a drive motor, and Vernier gimballing is employed so that the rotor and the momentum vector can be tilted actively with about one degree. The MW-X utilizes a suspension-control system for noise attenuation and active vibration suppression to reduce noise from the sensor surface. The actively controlled magnetic bearing wheels are shown to provide active damping of flexible structures by means of fully controllable translational bearing forces. The MW-X devices are of interest for applications to optical communications links, space telescopes, and earth-observation satellites with high resolutions.

  13. Combination volumetric and gravimetric sorption instrument for high accuracy measurements of methane adsorption

    Science.gov (United States)

    Burress, Jacob; Bethea, Donald; Troub, Brandon

    2017-05-01

    The accurate measurement of adsorbed gas up to high pressures (˜100 bars) is critical for the development of new materials for adsorbed gas storage. The typical Sievert-type volumetric method introduces accumulating errors that can become large at maximum pressures. Alternatively, gravimetric methods employing microbalances require careful buoyancy corrections. In this paper, we present a combination gravimetric and volumetric system for methane sorption measurements on samples between ˜0.5 and 1 g. The gravimetric method described requires no buoyancy corrections. The tandem use of the gravimetric method allows for a check on the highest uncertainty volumetric measurements. The sources and proper calculation of uncertainties are discussed. Results from methane measurements on activated carbon MSC-30 and metal-organic framework HKUST-1 are compared across methods and within the literature.

  14. Ultraviolet Raman lidar for high-accuracy profiling of aerosol extinction coefficient

    Institute of Scientific and Technical Information of China (English)

    Fei Gao; Xiaoquan Song; Yufeng Wang; Yi Zhou; Dengxin Hua

    2009-01-01

    An ultraviolet (UV) Raman lidar system at 354.7 nm has been developed for accurately measuring the aerosol extinction profiles. A spectroscopic filter combining a high-spectral-resolution grating with two narrowband mirrors is used to separate the vibrational Raman scattering signal of N2 at a central wave-length of 386.7 nm and the elastic scattering signal at 354.7 nm. The aerosol extinction is derived from the Raman scattering of N2 and the elastic scattering by the use of Raman method and Klett method, respectively. The derived results of aerosol extinction are used to compare the difference of two retrieval methods, and the preliminary experiment shows that the Raman lidar system operated in analog detection mode has the capability of measuring aerosol profiles up to a height of 3 km with a laser energy of 250 mJ and an integration time of 8 min.

  15. High Accuracy Tracking of Space-Borne Non-Cooperative Targets

    DEFF Research Database (Denmark)

    Pedersen, David Arge Klevang

    for the spacecraft to navigate safely and autonomously towards the target. These methods are applied on three distinct study cases, which are based on the platform of the microASC instrument. In relation to the Mars2020 rover, a structured light system is used to navigate the PIXL instrument towards the Martian...... the surface and to enhance the PIXL instrument's capabilities with highly accurate distance measurements. Optical observations of planetary bodies and satellites are utilized to determine the inertial position of a spacecraft. A software module is developed, tested and verified by both ground based and in......-ight observations, where the performanceover the complete operational envelope is characterized by simulations. The in-flight observations were captured onboard Juno, during the Earth flyby, by the microASC instrument, operating as an inertially controlled imager. The involvement in Juno's Earth Fly By operational...

  16. High accuracy measurements of dry mole fractions of carbon dioxide and methane in humid air

    Directory of Open Access Journals (Sweden)

    C. W. Rella

    2012-08-01

    Full Text Available Traditional techniques for measuring the mole fractions of greenhouse gas in the well-mixed atmosphere have required extremely dry sample gas streams (dew point < −25 °C to achieve the inter-laboratory compatibility goals set forth by the Global Atmospheric Watch program of the World Meteorological Organization (WMO/GAW for carbon dioxide (±0.1 ppm and methane (±2 ppb. Drying the sample gas to low levels of water vapor can be expensive, time-consuming, and/or problematic, especially at remote sites where access is difficult. Recent advances in optical measurement techniques, in particular Cavity Ring Down Spectroscopy (CRDS, have led to the development of highly stable and precise greenhouse gas analyzers capable of highly accurate measurements of carbon dioxide, methane, and water vapor. Unlike many older technologies, which can suffer from significant uncorrected interference from water vapor, these instruments permit for the first time accurate and precise greenhouse gas measurements that can meet the WMO/GAW inter-laboratory compatibility goals without drying the sample gas. In this paper, we present laboratory methodology for empirically deriving the water vapor correction factors, and we summarize a series of in-situ validation experiments comparing the measurements in humid gas streams to well-characterized dry-gas measurements. By using the manufacturer-supplied correction factors, the dry-mole fraction measurements have been demonstrated to be well within the GAW compatibility goals up to at least 1% water vapor. By determining the correction factors for individual instruments once at the start of life, this range can be extended to at least 2% over the life of the instrument, and if the correction factors are determined periodically over time, the evidence suggests that this range can be extended above 4%.

  17. Indexing Large Visual Vocabulary by Randomized Dimensions Hashing for High Quantization Accuracy: Improving the Object Retrieval Quality

    Science.gov (United States)

    Yang, Heng; Wang, Qing; He, Zhoucan

    The bag-of-visual-words approach, inspired by text retrieval methods, has proven successful in achieving high performance in object retrieval on large-scale databases. A key step of these methods is the quantization stage which maps the high-dimensional image feature vectors to discriminatory visual words. In this paper, we consider the quantization step as the nearest neighbor search in large visual vocabulary, and thus proposed a randomized dimensions hashing (RDH) algorithm to efficiently index and search the large visual vocabulary. The experimental results have demonstrated that the proposed algorithm can effectively increase the quantization accuracy compared to the vocabulary tree based methods which represent the state-of-the-art. Consequently, the object retrieval performance can be significantly improved by our method in the large-scale database.

  18. Social power and recognition of emotional prosody: High power is associated with lower recognition accuracy than low power.

    Science.gov (United States)

    Uskul, Ayse K; Paulmann, Silke; Weick, Mario

    2016-02-01

    Listeners have to pay close attention to a speaker's tone of voice (prosody) during daily conversations. This is particularly important when trying to infer the emotional state of the speaker. Although a growing body of research has explored how emotions are processed from speech in general, little is known about how psychosocial factors such as social power can shape the perception of vocal emotional attributes. Thus, the present studies explored how social power affects emotional prosody recognition. In a correlational study (Study 1) and an experimental study (Study 2), we show that high power is associated with lower accuracy in emotional prosody recognition than low power. These results, for the first time, suggest that individuals experiencing high or low power perceive emotional tone of voice differently.

  19. Hybrid single-packet IP traceback with low storage and high accuracy.

    Science.gov (United States)

    Yang, Ming Hour

    2014-01-01

    Traceback schemes have been proposed to trace the sources of attacks that usually hide by spoofing their IP addresses. Among these methods, schemes using packet logging can achieve single-packet traceback. But packet logging demands high storage on routers and therefore makes IP traceback impractical. For lower storage requirement, packet logging and packet marking are fused to make hybrid single-packet IP traceback. Despite such attempts, their storage still increases with packet numbers. That is why RIHT bounds its storage with path numbers to guarantee low storage. RIHT uses IP header's ID and offset fields to mark packets, so it inevitably suffers from fragment and drop issues for its packet reassembly. Although the 16-bit hybrid IP traceback schemes, for example, MORE, can mitigate the fragment problem, their storage requirement grows up with packet numbers. To solve the storage and fragment problems in one shot, we propose a single-packet IP traceback scheme that only uses packets' ID field for marking. Our major contributions are as follows: (1) our fragmented packets with tracing marks can be reassembled; (2) our storage is not affected by packet numbers; (3) it is the first hybrid single-packet IP traceback scheme to achieve zero false positive and zero false negative rates.

  20. High-accuracy acoustic detection of nonclassical component of material nonlinearity.

    Science.gov (United States)

    Haupert, Sylvain; Renaud, Guillaume; Rivière, Jacques; Talmant, Maryline; Johnson, Paul A; Laugier, Pascal

    2011-11-01

    The aim is to assess the nonclassical component of material nonlinearity in several classes of materials with weak, intermediate, and high nonlinear properties. In this contribution, an optimized nonlinear resonant ultrasound spectroscopy (NRUS) measuring and data processing protocol applied to small samples is described. The protocol is used to overcome the effects of environmental condition changes that take place during an experiment, and that may mask the intrinsic nonlinearity. External temperature fluctuation is identified as a primary source of measurement contamination. For instance, a variation of 0.1 °C produced a frequency variation of 0.01%, which is similar to the expected nonlinear frequency shift for weakly nonlinear materials. In order to overcome environmental effects, the reference frequency measurements are repeated before each excitation level and then used to compute nonlinear parameters. Using this approach, relative resonant frequency shifts of 10(-5) can be measured, which is below the limit of 10(-4) often considered as the limit of NRUS sensitivity under common experimental conditions. Due to enhanced sensitivity resulting from the correction procedure applied in this work, nonclassical nonlinearity in materials that before have been assumed to only be classically nonlinear in past work (steel, brass, and aluminum) is reported.

  1. Determination of the QCD Λ-parameter and the accuracy of perturbation theory at high energies

    Energy Technology Data Exchange (ETDEWEB)

    Dalla Brida, Mattia [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC; Fritzsch, Patrick [Univ. Autonoma de Madrid (Spain). Inst. de Fisica Teorica UAM/CSIC; Korzec, Tomasz [Wuppertal Univ. (Germany). Dept. of Physics; Ramos, Alberto [CERN - European Organization for Nuclear Research, Geneva (Switzerland). Theory Div.; Sint, Stefan [Trinity College Dublin (Ireland). School of Mathematics; Sommer, Rainer [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC; Humboldt-Universitaet, Berlin (Germany). Inst. fuer Physik; Collaboration: ALPHA Collaboration

    2016-04-15

    We discuss the determination of the strong coupling α{sub MS}(m{sub Z}) or equivalently the QCD Λ-parameter. Its determination requires the use of perturbation theory in α{sub s}(μ) in some scheme, s, and at some energy scale μ. The higher the scale μ the more accurate perturbation theory becomes, owing to asymptotic freedom. As one step in our computation of the Λ-parameter in three-flavor QCD, we perform lattice computations in a scheme which allows us to non-perturbatively reach very high energies, corresponding to α{sub s}=0.1 and below. We find that (continuum) perturbation theory is very accurate there, yielding a three percent error in the Λ-parameter, while data around α{sub s}∼0.2 is clearly insufficient to quote such a precision. It is important to realize that these findings are expected to be generic, as our scheme has advantageous properties regarding the applicability of perturbation theory.

  2. Temporal Stability of the Velodyne HDL-64E S2 Scanner for High Accuracy Scanning Applications

    Directory of Open Access Journals (Sweden)

    Craig Glennie

    2011-03-01

    Full Text Available The temporal stability and static calibration and analysis of the Velodyne HDL‑64E S2 scanning LiDAR system is discussed and analyzed. The mathematical model for measurements for the HDL-64E S2 scanner is updated to include misalignments between the angular encoder and scanner axis of rotation, which are found to be a marginally significant source of error. It is reported that the horizontal and vertical laser offsets cannot reliably be obtained with the current calibration model due to their high correlation with the horizontal and vertical offsets. By analyzing observations from two separate HDL-64E S2 scanners it was found that the temporal stability of the horizontal angle offset is near the quantization level of the encoder, but the vertical angular offset, distance offset and distance scale are slightly larger than expected. This is felt to be due to long term variations in the scanner range, whose root cause is as of yet unidentified. Nevertheless, a temporally averaged calibration dataset for each of the scanners resulted in a 25% improvement in the 3D planar misclosure residual RMSE over the standard factory calibration model.

  3. High-accuracy local positioning network for the alignment of the Mu2e experiment.

    Energy Technology Data Exchange (ETDEWEB)

    Hejdukova, Jana B. [Czech Technical Univ., Prague (Czech Republic)

    2017-06-01

    This Diploma thesis describes the establishment of a high-precision local positioning network and accelerator alignment for the Mu2e physics experiment. The process of establishing new network consists of few steps: design of the network, pre-analysis, installation works, measurements of the network and making adjustments. Adjustments were performed using two approaches. First is a geodetic approach of taking into account the Earth’s curvature and the metrological approach of a pure 3D Cartesian system on the other side. The comparison of those two approaches is performed and evaluated in the results and compared with expected differences. The effect of the Earth’s curvature was found to be significant for this kind of network and should not be neglected. The measurements were obtained with Absolute Tracker AT401, leveling instrument Leica DNA03 and gyrotheodolite DMT Gyromat 2000. The coordinates of the points of the reference network were determined by the Least Square Meth od and the overall view is attached as Annexes.

  4. High-accuracy, high-precision, high-resolution, continuous monitoring of urban greenhouse gas emissions? Results to date from INFLUX

    Science.gov (United States)

    Davis, K. J.; Brewer, A.; Cambaliza, M. O. L.; Deng, A.; Hardesty, M.; Gurney, K. R.; Heimburger, A. M. F.; Karion, A.; Lauvaux, T.; Lopez-Coto, I.; McKain, K.; Miles, N. L.; Patarasuk, R.; Prasad, K.; Razlivanov, I. N.; Richardson, S.; Sarmiento, D. P.; Shepson, P. B.; Sweeney, C.; Turnbull, J. C.; Whetstone, J. R.; Wu, K.

    2015-12-01

    The Indianapolis Flux Experiment (INFLUX) is testing the boundaries of our ability to use atmospheric measurements to quantify urban greenhouse gas (GHG) emissions. The project brings together inventory assessments, tower-based and aircraft-based atmospheric measurements, and atmospheric modeling to provide high-accuracy, high-resolution, continuous monitoring of emissions of GHGs from the city. Results to date include a multi-year record of tower and aircraft based measurements of the urban CO2 and CH4 signal, long-term atmospheric modeling of GHG transport, and emission estimates for both CO2 and CH4 based on both tower and aircraft measurements. We will present these emissions estimates, the uncertainties in each, and our assessment of the primary needs for improvements in these emissions estimates. We will also present ongoing efforts to improve our understanding of atmospheric transport and background atmospheric GHG mole fractions, and to disaggregate GHG sources (e.g. biogenic vs. fossil fuel CO2 fluxes), topics that promise significant improvement in urban GHG emissions estimates.

  5. Analysis of bromotryptophan and hydroxyproline modifications by high-resolution, high-accuracy precursor ion scanning utilizing fragment ions with mass-deficient mass tags.

    Science.gov (United States)

    Steen, Hanno; Mann, Matthias

    2002-12-15

    Protein modifications are often detected by precursor ion scanning. When quadrupole TOF mass spectrometers are used for precursor ion scanning with high-resolution, high-accuracy fragment ion selection, "reporter" ions are required to have a unique mass within +/-0.04 Da or less instead of +/-0.5 Da on triple quadrupole mass spectrometers, the traditional instrument used for precursor ion scanning. Thus, characteristic fragment ions can be utilized even if other fragment ions have the same nominal mass as long as the characteristic fragment ions are slightly mass deficient as compared to the other fragments, i.e., when they have an inherent mass-deficient mass tag. Here, the immonium ions of bromotryptophan and hydroxyproline are described as two fragment ions characteristic for tryptophan-brominated and proline-hydroxylated peptides, respectively. The "reporter" ion of trytophan-brominated peptides is highly mass deficient due to the presence of bromine, thereby allowing the selective detection of these species and the distinction from other dipeptidic a-, b-, and y-fragment ions by high-resolution, high-accuracy precursor ion scanning. This strategy also enables the differentiation between precursors giving rise to the oxygen-containing immonium ion of hydroxyproline and precursors of the immonium ions of near-ubiquitous leucine/isoleucine. Both immonium ions have the same nominal mass of 86 Da, but the exact masses differ by less than 0.04 Da. High-resolution, high-accuracy precursor ion scanning enabled the identification of proline-hydroxylated and tryptophan-brominated species and the directed analysis of species carrying these modifications in a highly complex Conus textile conotoxin mixture. This lead to the characterization of one novel C. textile conotoxin containing a bromotryptophan residue and one novel C. textile conotoxin carrying two hydroxyproline residues.

  6. Real-time integration of a tactical-grade IMU and GPS for high-accuracy positioning and navigation

    Science.gov (United States)

    Petovello, Mark G.

    2003-10-01

    The integration of the Global Positioning System (CPS) and Inertial Navigation Systems (INSs) is often used to provide accurate positioning and navigation information. For applications requiring the highest accuracy, the quality of the inertial sensors required is usually assumed to be very high. This dissertation investigates the integration of CPS with a tactical-grade Inertial Measurement Unit (IMU) for centimetre-level navigation in real-time. Different GPS/INS integration strategies are investigated to assess their relative performance in terms of position and velocity accuracy during partial and complete data outages, carrier phase ambiguity resolution after such data outages, and the overall statistical reliability of the system. In terms of statistical reliability, the traditional equations used in dynamic systems are redeveloped in light of some practical considerations, including centralized and decentralized filter architectures, and sequential versus simultaneous measurement updating. Results show that the integrated solution outperforms the GPS-only approach in all areas. The difference between loose and tight integration strategies was most significant for ambiguity resolution and system reliability. The integrated solution is capable of providing decimetre-level accuracy or better for durations of about five or ten seconds when a complete or partial CPS outage is simulated. This level of accuracy, extended over longer time intervals, is shown to reduce the time required to resolve the L1 ambiguities by an average of about 50% or more for data outages as long as 30 seconds when using a tight integration strategy. More importantly, the reliability of the ambiguity resolution process is improved with the integrated system. Statistical reliability parameters are also dramatically better when using the integrated system with the ability of detecting a single-cycle cycle slip being better and more consistent, relative to GPS-only. The effect of undetected

  7. A new TEC interpolation method based on the least squares collocation for high accuracy regional ionospheric maps

    Science.gov (United States)

    Krypiak-Gregorczyk, Anna; Wielgosz, Paweł; Jarmołowski, Wojciech

    2017-04-01

    The ionosphere plays a crucial role in space weather that affects satellite navigation as the ionospheric delay is one of the major errors in GNSS. On the other hand, GNSS observations are widely used to determine the amount of ionospheric total electron content (TEC). An important aspect in the electron content estimation at regional and global scale is adopting the appropriate interpolation strategy. In this paper we propose and validate a new method for regional TEC modeling based on least squares collocation (LSC) with noise variance estimation. This method allows for providing accurate TEC maps with high spatial and temporal resolution. Such maps may be used to support precise GNSS positioning and navigation, e.g. in RTK mode and also in the ionosphere studies. To test applicability of new TEC maps to positioning, double-difference ionospheric corrections were derived from the maps and their accuracy was analyzed. In addition, the corrections were applied to GNSS positioning and validated in ambiguity resolution domain. The tests were carried out during a strong ionospheric storm when the ionosphere is particularly difficult to model. The performance of the new approach was compared to IGS and UPC global, and CODE regional TEC maps. The results showed an advantage of our solution with resulting accuracy of the relative ionospheric corrections usually better than 10 cm, even during the ionospheric disturbances. This proves suitability of our regional TEC maps for, e.g. supporting fast ambiguity resolution in kinematic GNSS positioning.

  8. Location accuracy evaluation of lightning location systems using natural lightning flashes recorded by a network of high-speed cameras

    Science.gov (United States)

    Alves, J.; Saraiva, A. C. V.; Campos, L. Z. D. S.; Pinto, O., Jr.; Antunes, L.

    2014-12-01

    This work presents a method for the evaluation of location accuracy of all Lightning Location System (LLS) in operation in southeastern Brazil, using natural cloud-to-ground (CG) lightning flashes. This can be done through a multiple high-speed cameras network (RAMMER network) installed in the Paraiba Valley region - SP - Brazil. The RAMMER network (Automated Multi-camera Network for Monitoring and Study of Lightning) is composed by four high-speed cameras operating at 2,500 frames per second. Three stationary black-and-white (B&W) cameras were situated in the cities of São José dos Campos and Caçapava. A fourth color camera was mobile (installed in a car), but operated in a fixed location during the observation period, within the city of São José dos Campos. The average distance among cameras was 13 kilometers. Each RAMMER sensor position was determined so that the network can observe the same lightning flash from different angles and all recorded videos were GPS (Global Position System) time stamped, allowing comparisons of events between cameras and the LLS. The RAMMER sensor is basically composed by a computer, a Phantom high-speed camera version 9.1 and a GPS unit. The lightning cases analyzed in the present work were observed by at least two cameras, their position was visually triangulated and the results compared with BrasilDAT network, during the summer seasons of 2011/2012 and 2012/2013. The visual triangulation method is presented in details. The calibration procedure showed an accuracy of 9 meters between the accurate GPS position of the object triangulated and the result from the visual triangulation method. Lightning return stroke positions, estimated with the visual triangulation method, were compared with LLS locations. Differences between solutions were not greater than 1.8 km.

  9. Static Calibration and Analysis of the Velodyne HDL-64E S2 for High Accuracy Mobile Scanning

    Directory of Open Access Journals (Sweden)

    Craig Glennie

    2010-06-01

    Full Text Available The static calibration and analysis of the Velodyne HDL-64E S2 scanning LiDAR system is presented and analyzed. The mathematical model for measurements for the HDL-64E S2 scanner is derived and discussed. A planar feature based least squares adjustment approach is presented and utilized in a minimally constrained network in order to derive an optimal solution for the laser’s internal calibration parameters. Finally, the results of the adjustment along with a detailed examination of the adjustment residuals are given. A three-fold improvement in the planar misclosure residual RMSE over the standard factory calibration model was achieved by the proposed calibration. Results also suggest that there may still be some unmodelled distortions in the range measurements from the scanner. However, despite this, the overall precision of the adjusted laser scanner data appears to make it a viable choice for high accuracy mobile scanning applications.

  10. High-accuracy measurements of snow Bidirectional Reflectance Distribution Function at visible and NIR wavelengths – comparison with modelling results

    Directory of Open Access Journals (Sweden)

    Y. Arnaud

    2009-09-01

    Full Text Available High-accuracy measurements of snow Bidirectional Reflectance Distribution Function (BRDF were performed for four natural snow samples with a spectrogonio-radiometer in the 500–2600 nm wavelength range. These measurements are one of the first set of direct snow BRDF values over a wide range of lighting and viewing geometry. They were compared to BRDF calculated with two optical models. Variations of the snow anisotropy factor with lighting geometry, wavelength and snow physical properties were investigated. Results show that at wavelengths with small penetration depth, scattering mainly occurs in the very top layers and the anisotropy factor is controlled by the phase function. In this condition, forward scattering peak or double scattering peak is observed. In constrast at shorter wavelengths, the penetration of the radiation is much deeper and the number of scattering events increases. The anisotropy factor is thus nearly constant and decreases at grazing observation angles.

  11. High-accuracy measurements of snow Bidirectional Reflectance Distribution Function at visible and NIR wavelengths - comparison with modelling results

    Science.gov (United States)

    Dumont, M.; Brissaud, O.; Picard, G.; Schmitt, B.; Gallet, J.-C.; Arnaud, Y.

    2010-03-01

    High-accuracy measurements of snow Bidirectional Reflectance Distribution Function (BRDF) were performed for four natural snow samples with a spectrogonio-radiometer in the 500-2600 nm wavelength range. These measurements are one of the first sets of direct snow BRDF values over a wide range of lighting and viewing geometry. They were compared to BRDF calculated with two optical models. Variations of the snow anisotropy factor with lighting geometry, wavelength and snow physical properties were investigated. Results show that at wavelengths with small penetration depth, scattering mainly occurs in the very top layers and the anisotropy factor is controlled by the phase function. In this condition, forward scattering peak or double scattering peak is observed. In contrast at shorter wavelengths, the penetration of the radiation is much deeper and the number of scattering events increases. The anisotropy factor is thus nearly constant and decreases at grazing observation angles. The whole dataset is available on demand from the corresponding author.

  12. Fundamental M-dwarf parameters from high-resolution spectra using PHOENIX ACES models: I. Parameter accuracy and benchmark stars

    CERN Document Server

    Passegger, Vera Maria; Reiners, Ansgar

    2016-01-01

    M-dwarf stars are the most numerous stars in the Universe; they span a wide range in mass and are in the focus of ongoing and planned exoplanet surveys. To investigate and understand their physical nature, detailed spectral information and accurate stellar models are needed. We use a new synthetic atmosphere model generation and compare model spectra to observations. To test the model accuracy, we compared the models to four benchmark stars with atmospheric parameters for which independent information from interferometric radius measurements is available. We used $\\chi^2$ -based methods to determine parameters from high-resolution spectroscopic observations. Our synthetic spectra are based on the new PHOENIX grid that uses the ACES description for the equation of state. This is a model generation expected to be especially suitable for the low-temperature atmospheres. We identified suitable spectral tracers of atmospheric parameters and determined the uncertainties in $T_{\\rm eff}$, $\\log{g}$, and [Fe/H] resul...

  13. Novel technique to suppress hydrocarbon contamination for high accuracy determination of carbon content in steel by FE-EPMA

    Science.gov (United States)

    Yamashita, Takako; Tanaka, Yuji; Yagoshi, Masayasu; Ishida, Kiyohito

    2016-07-01

    In multiphase steels, control of the carbon contents in the respective phases is the most important factor in alloy design for achieving high strength and high ductility. However, it is unusually difficult to determine the carbon contents in multiphase structures with high accuracy by electron probe microanalysis (EPMA) due to the unavoidable effect of hydrocarbon contamination during measurements. We have investigated new methods for suppressing hydrocarbon contamination during field emission (FE) EPMA measurements as well as a conventional liquid nitrogen trap. Plasma cleaner inside the specimen chamber results in a improvement of carbon-content determination by point analysis, increasing precision tenfold from the previous 0.1 mass%C to 0.01 mass%C. Stage heating at about 100 °C dramatically suppresses contamination growth during continuous point measurement and mapping. By the combination of above two techniques, we successfully visualized the two-dimensional carbon distribution in a dual-phase steel. It was also noted that the carbon concentrations at the ferrite/martensite interfaces were not the same across all interfaces, and local variation was observed. The developed technique is expected to be a powerful tool for understanding the mechanisms of mechanical properties and microstructural evolution, thereby contributing to the design of new steel products with superior properties.

  14. High-Accuracy Tidal Flat Digital Elevation Model Construction Using TanDEM-X Science Phase Data

    Science.gov (United States)

    Lee, Seung-Kuk; Ryu, Joo-Hyung

    2017-01-01

    This study explored the feasibility of using TanDEM-X (TDX) interferometric observations of tidal flats for digital elevation model (DEM) construction. Our goal was to generate high-precision DEMs in tidal flat areas, because accurate intertidal zone data are essential for monitoring coastal environment sand erosion processes. To monitor dynamic coastal changes caused by waves, currents, and tides, very accurate DEMs with high spatial resolution are required. The bi- and monostatic modes of the TDX interferometer employed during the TDX science phase provided a great opportunity for highly accurate intertidal DEM construction using radar interferometry with no time lag (bistatic mode) or an approximately 10-s temporal baseline (monostatic mode) between the master and slave synthetic aperture radar image acquisitions. In this study, DEM construction in tidal flat areas was first optimized based on the TDX system parameters used in various TDX modes. We successfully generated intertidal zone DEMs with 57-m spatial resolutions and interferometric height accuracies better than 0.15 m for three representative tidal flats on the west coast of the Korean Peninsula. Finally, we validated these TDX DEMs against real-time kinematic-GPS measurements acquired in two tidal flat areas; the correlation coefficient was 0.97 with a root mean square error of 0.20 m.

  15. Novel technique to suppress hydrocarbon contamination for high accuracy determination of carbon content in steel by FE-EPMA.

    Science.gov (United States)

    Yamashita, Takako; Tanaka, Yuji; Yagoshi, Masayasu; Ishida, Kiyohito

    2016-07-19

    In multiphase steels, control of the carbon contents in the respective phases is the most important factor in alloy design for achieving high strength and high ductility. However, it is unusually difficult to determine the carbon contents in multiphase structures with high accuracy by electron probe microanalysis (EPMA) due to the unavoidable effect of hydrocarbon contamination during measurements. We have investigated new methods for suppressing hydrocarbon contamination during field emission (FE) EPMA measurements as well as a conventional liquid nitrogen trap. Plasma cleaner inside the specimen chamber results in a improvement of carbon-content determination by point analysis, increasing precision tenfold from the previous 0.1 mass%C to 0.01 mass%C. Stage heating at about 100 °C dramatically suppresses contamination growth during continuous point measurement and mapping. By the combination of above two techniques, we successfully visualized the two-dimensional carbon distribution in a dual-phase steel. It was also noted that the carbon concentrations at the ferrite/martensite interfaces were not the same across all interfaces, and local variation was observed. The developed technique is expected to be a powerful tool for understanding the mechanisms of mechanical properties and microstructural evolution, thereby contributing to the design of new steel products with superior properties.

  16. Characterization of an experimental arrangement to measure position of particles in 3D with a high accuracy

    Science.gov (United States)

    Martínez González, A.; Guerrero Viramontes, J. A.; Moreno Hernández, D.

    2011-09-01

    Single particle position calculation in three dimensions (3D) with high accuracy is the very important in several branches of science. On the other hand, the use of in-line holography to study very small objects in a dynamic volume is a technique of importance for scientists and engineers across a variety of disciplines for obtaining information about size, shape, trajectory and velocity of small objects such as dust particles. However, in general for in-line holography, accurate determination of the object's position in the optical axis direction is difficult. In order to overcome this shortcoming, we proposed to use in-line holography set up to record particle images in two orthogonal forward configurations. In this study, we avoid digital holography reconstruction to calculate particle position. To determine particle position, the proposed method is based on the calculation of the size and position of the central spot size (CSS) of a particle diffraction image. The size of the CSS is calculated by using the Continuous Wavelet Transform (CWT) and Continuous Hough Transforms (CHT), an then the size of the CSS is related to a calibration curve calculated experimentally in order to determine the "z" particle position and centroid of the CSS render the "x-y" position of a particle image. The procedure proposed in this work to determine the 3D particle position is so simple since it avoids a complicated experimental set-up and several computational steps in order to obtain the 3D position of the particles. Our approach offers the following advantages: First, the mathematical accuracy, light illumination as well as particle and medium refractive indexes are used during the analysis. Second, it is not required to resolve the size of particle since we calculate only the size of CSS of a diffraction particle image pattern.

  17. Optimization and design of inter-stage amplifier with wide output swing,high speed and high accuracy

    Institute of Scientific and Technical Information of China (English)

    ZHAO Yi-qiang; SUN Quan; GAO Jing

    2008-01-01

    To satisfy the design requirements of analog-to-digital converter (ADC) of high speed sampling sys-tem in an infrared focal plane array tester with 1024 × 1024 pixels, a first inter-stage amplifier of 12-bit 40-Msample/s pipelined ADC was designed with 0.35 μm CMOS technology. On the basis of traditional two-stage amplifier, the cross-coupled class AB output stage and cascode compensation were adopted to improve the out-put voltage swing and bandwidth. Power dissipation was optimized with math tools. Circuit and layout design were completed. Simulation results show that the designed amplifier has good performance of 95 dB de gain, ±2 V output voltage swing, 190 MHz bandwidth and 63° phase margin with feedback factor 1/4, 33 mW pow-er dissipation and so on, which can meet the system requirements.

  18. Comparison of the temperature accuracy between smart phone based and high-end thermal cameras using a temperature gradient phantom

    Science.gov (United States)

    Klaessens, John H.; van der Veen, Albert; Verdaasdonk, Rudolf M.

    2017-03-01

    Recently, low cost smart phone based thermal cameras are being considered to be used in a clinical setting for monitoring physiological temperature responses such as: body temperature change, local inflammations, perfusion changes or (burn) wound healing. These thermal cameras contain uncooled micro-bolometers with an internal calibration check and have a temperature resolution of 0.1 degree. For clinical applications a fast quality measurement before use is required (absolute temperature check) and quality control (stability, repeatability, absolute temperature, absolute temperature differences) should be performed regularly. Therefore, a calibrated temperature phantom has been developed based on thermistor heating on both ends of a black coated metal strip to create a controllable temperature gradient from room temperature 26 °C up to 100 °C. The absolute temperatures on the strip are determined with software controlled 5 PT-1000 sensors using lookup tables. In this study 3 FLIR-ONE cameras and one high end camera were checked with this temperature phantom. The results show a relative good agreement between both low-cost and high-end camera's and the phantom temperature gradient, with temperature differences of 1 degree up to 6 degrees between the camera's and the phantom. The measurements were repeated as to absolute temperature and temperature stability over the sensor area. Both low-cost and high-end thermal cameras measured relative temperature changes with high accuracy and absolute temperatures with constant deviations. Low-cost smart phone based thermal cameras can be a good alternative to high-end thermal cameras for routine clinical measurements, appropriate to the research question, providing regular calibration checks for quality control.

  19. Precision of high-resolution multibeam echo sounding coupled with high-accuracy positioning in a shallow water coastal environment

    Science.gov (United States)

    Ernstsen, Verner B.; Noormets, Riko; Hebbeln, Dierk; Bartholomä, Alex; Flemming, Burg W.

    2006-09-01

    Over 4 years, repetitive bathymetric measurements of a shipwreck in the Grådyb tidal inlet channel in the Danish Wadden Sea were carried out using a state-of-the-art high-resolution multibeam echosounder (MBES) coupled with a real-time long range kinematic (LRK™) global positioning system. Seven measurements during a single survey in 2003 ( n=7) revealed a horizontal and vertical precision of the MBES system of ±20 and ±2 cm, respectively, at a 95% confidence level. By contrast, four annual surveys from 2002 to 2005 ( n=4) yielded a horizontal and vertical precision (at 95% confidence level) of only ±30 and ±8 cm, respectively. This difference in precision can be explained by three main factors: (1) the dismounting of the system between the annual surveys, (2) rougher sea conditions during the survey in 2004 and (3) the limited number of annual surveys. In general, the precision achieved here did not correspond to the full potential of the MBES system, as this could certainly have been improved by an increase in coverage density (soundings/m2), achievable by reducing the survey speed of the vessel. Nevertheless, precision was higher than that reported to date for earlier offshore test surveys using comparable equipment.

  20. First results using a new technology for measuring masses of very short-lived nuclides with very high accuracy the MISTRAL program at ISOLDE

    CERN Document Server

    Monsanglant, C; Audi, G; Bollen, G; Borcea, C; Conreur, G; Cousin, R; Doubre, H; Duma, M; Jacotin, M; Henry, S; Képinski, J F; Kluge, H J; Lebée, G; Le Scornet, G; Lunney, S; De Saint-Simon, M; Scheidenberger, C; Thibault, C

    1999-01-01

    MISTRAL is an experimental program to measure masses of very short- lived nuclides (T$_{1/2}$ down to a few ms), with a very high accuracy (a few 10$^{-7}$). There were three data taking periods with radioactive beams and 22 masses of isotopes of Ne, Na*, Mg, Al*, K, Ca, and Ti were measured. The systematic errors are now under control at the level of 8$\\TIMES10^{-7}$, allowing to come close to the expected accuracy. Even for the very weakly produced $^{30}$Na (1 ion at the detector per proton burst), the final accuracy is 7$\\TIMES10^{-7}$. (15 refs).

  1. Parallel High Order Accuracy Methods Applied to Non-Linear Hyperbolic Equations and to Problems in Materials Sciences

    Energy Technology Data Exchange (ETDEWEB)

    Jan Hesthaven

    2012-02-06

    Final report for DOE Contract DE-FG02-98ER25346 entitled Parallel High Order Accuracy Methods Applied to Non-Linear Hyperbolic Equations and to Problems in Materials Sciences. Principal Investigator Jan S. Hesthaven Division of Applied Mathematics Brown University, Box F Providence, RI 02912 Jan.Hesthaven@Brown.edu February 6, 2012 Note: This grant was originally awarded to Professor David Gottlieb and the majority of the work envisioned reflects his original ideas. However, when Prof Gottlieb passed away in December 2008, Professor Hesthaven took over as PI to ensure proper mentoring of students and postdoctoral researchers already involved in the project. This unusual circumstance has naturally impacted the project and its timeline. However, as the report reflects, the planned work has been accomplished and some activities beyond the original scope have been pursued with success. Project overview and main results The effort in this project focuses on the development of high order accurate computational methods for the solution of hyperbolic equations with application to problems with strong shocks. While the methods are general, emphasis is on applications to gas dynamics with strong shocks.

  2. High sensitivity and accuracy dissolved oxygen (DO) detection by using PtOEP/poly(MMA-co-TFEMA) sensing film

    Science.gov (United States)

    Zhang, Ke; Zhang, Honglin; Wang, Ying; Tian, Yanqing; Zhao, Jiupeng; Li, Yao

    2017-01-01

    Fluorinated acrylate polymer has received great interest in recent years due to its extraordinary characteristics such as high oxygen permeability, good stability, low surface energy and refractive index. In this work, platinum octaethylporphyrin/poly(methylmethacrylate-co-trifluoroethyl methacrylate) (PtOEP/poly(MMA-co-TFEMA)) oxygen sensing film was prepared by the immobilizing of PtOEP in a poly(MMA-co-TFEMA) matrix and the technological readiness of optical properties was established based on the principle of luminescence quenching. It was found that the oxygen-sensing performance could be improved by optimizing the monomer ratio (MMA/TFEMA = 1:1), tributylphosphate(TBP, 0.05 mL) and PtOEP (5 μg) content. Under this condition, the maximum quenching ratio I0/I100 of the oxygen sensing film is obtained to be about 8.16, Stern-Volmer equation is I0/I = 1.003 + 2.663[O2] (R2 = 0.999), exhibiting a linear relationship, good photo-stability, high sensitivity and accuracy. Finally, the synthesized PtOEP/poly(MMA-co-TFEMA) sensing film was used for DO detection in different water samples.

  3. Emergence of realism: Enhanced visual artistry and high accuracy of visual numerosity representation after left prefrontal damage.

    Science.gov (United States)

    Takahata, Keisuke; Saito, Fumie; Muramatsu, Taro; Yamada, Makiko; Shirahase, Joichiro; Tabuchi, Hajime; Suhara, Tetsuya; Mimura, Masaru; Kato, Motoichiro

    2014-05-01

    Over the last two decades, evidence of enhancement of drawing and painting skills due to focal prefrontal damage has accumulated. It is of special interest that most artworks created by such patients were highly realistic ones, but the mechanism underlying this phenomenon remains to be understood. Our hypothesis is that enhanced tendency of realism was associated with accuracy of visual numerosity representation, which has been shown to be mediated predominantly by right parietal functions. Here, we report a case of left prefrontal stroke, where the patient showed enhancement of artistic skills of realistic painting after the onset of brain damage. We investigated cognitive, functional and esthetic characteristics of the patient׳s visual artistry and visual numerosity representation. Neuropsychological tests revealed impaired executive function after the stroke. Despite that, the patient׳s visual artistry related to realism was rather promoted across the onset of brain damage as demonstrated by blind evaluation of the paintings by professional art reviewers. On visual numerical cognition tasks, the patient showed higher performance in comparison with age-matched healthy controls. These results paralleled increased perfusion in the right parietal cortex including the precuneus and intraparietal sulcus. Our data provide new insight into mechanisms underlying change in artistic style due to focal prefrontal lesion.

  4. High-accuracy diagnostic tool for electron cloud observation in the LHC based on synchronous phase measurements

    Science.gov (United States)

    Esteban Müller, J. F.; Baudrenghien, P.; Mastoridis, T.; Shaposhnikova, E.; Valuch, D.

    2015-11-01

    Electron cloud effects, which include heat load in the cryogenic system, pressure rise, and beam instabilities, are among the main intensity limitations for the LHC operation with 25 ns spaced bunches. A new observation tool was proposed and developed to monitor the e-cloud activity and it has already been used successfully during the LHC run 1 (2010-2012) and it is being intensively used in operation during the start of the LHC run 2 (2015-2018). It is based on the fact that the power loss of each bunch due to e-cloud can be estimated using bunch-by-bunch measurement of the synchronous phase. The measurements were done using the existing beam phase module of the low-level rf control system. In order to achieve the very high accuracy required, corrections for reflection in the cables and for systematic errors need to be applied followed by a post-processing of the measurements. Results clearly show the e-cloud buildup along the bunch trains and its time evolution during each LHC fill as well as from fill to fill. Measurements during the 2012 LHC scrubbing run reveal a progressive reduction in the e-cloud activity and therefore a decrease in the secondary electron yield. The total beam power loss can be computed as a sum of the contributions from all bunches and compared with the heat load deposited in the cryogenic system.

  5. High Accuracy Potential Energy Surface, Dipole Moment Surface, Rovibrational Energies and Line List Calculations for ^{14}NH_3

    Science.gov (United States)

    Coles, Phillip; Yurchenko, Sergei N.; Polyansky, Oleg; Kyuberis, Aleksandra; Ovsyannikov, Roman I.; Zobov, Nikolay Fedorovich; Tennyson, Jonathan

    2017-06-01

    We present a new spectroscopic potential energy surface (PES) for ^{14}NH_3, produced by refining a high accuracy ab initio PES to experimental energy levels taken predominantly from MARVEL. The PES reproduces 1722 matched J=0-8 experimental energies with a root-mean-square error of 0.035 cm-1 under 6000 cm^{-1} and 0.059 under 7200 cm^{-1}. In conjunction with a new DMS calculated using multi reference configuration interaction (MRCI) and H=aug-cc-pVQZ, N=aug-cc-pWCVQZ basis sets, an infrared (IR) line list has been computed which is suitable for use up to 2000 K. The line list is used to assign experimental lines in the 7500 - 10,500 cm^{-1} region and previously unassigned lines in HITRAN in the 6000-7000 cm^{-1} region. Oleg L. Polyansky, Roman I. Ovsyannikov, Aleksandra A. Kyuberis, Lorenzo Lodi, Jonathan Tennyson, Andrey Yachmenev, Sergei N. Yurchenko, Nikolai F. Zobov, J. Mol. Spec., 327 (2016) 21-30 Afaf R. Al Derzia, Tibor Furtenbacher, Jonathan Tennyson, Sergei N. Yurchenko, Attila G. Császár, J. Quant. Spectrosc. Rad. Trans., 161 (2015) 117-130

  6. High-accuracy measurements of snow Bidirectional Reflectance Distribution Function at visible and NIR wavelengths – comparison with modelling results

    Directory of Open Access Journals (Sweden)

    M. Dumont

    2010-03-01

    Full Text Available High-accuracy measurements of snow Bidirectional Reflectance Distribution Function (BRDF were performed for four natural snow samples with a spectrogonio-radiometer in the 500–2600 nm wavelength range. These measurements are one of the first sets of direct snow BRDF values over a wide range of lighting and viewing geometry. They were compared to BRDF calculated with two optical models. Variations of the snow anisotropy factor with lighting geometry, wavelength and snow physical properties were investigated. Results show that at wavelengths with small penetration depth, scattering mainly occurs in the very top layers and the anisotropy factor is controlled by the phase function. In this condition, forward scattering peak or double scattering peak is observed. In contrast at shorter wavelengths, the penetration of the radiation is much deeper and the number of scattering events increases. The anisotropy factor is thus nearly constant and decreases at grazing observation angles. The whole dataset is available on demand from the corresponding author.

  7. The LLNL High Accuracy Volume Renderer for Unstructured Data: Capabilities, Current Limits, and Potential for ASCI/VIEWS Deployment

    Energy Technology Data Exchange (ETDEWEB)

    Williams, P L; Max, N L

    2001-06-04

    This report describes a volume rendering system for unstructured data, especially finite element data, that creates images with very high accuracy. The system will currently handle meshes whose cells are either linear or quadratic tetrahedra, or meshes with mixed cell types: tetrahedra, bricks, prisms, and pyramids. The cells may have nonplanar facets. Whenever possible, exact mathematical solutions for the radiance integrals and for interpolation are used. Accurate semitransparent shaded isosurfaces may be embedded in the volume rendering. For very small cells, subpixel accumulation by splatting is used to avoid sampling error. A new exact and efficient visibility ordering algorithm is described. The most accurate images are generated in software, however, more efficient algorithms utilizing graphics hardware may also be selected. The report describes the parallelization of the system for a distributed-shared memory multiprocessor machine, and concludes by discussing the system's limits, desirable future work, and ways to extend the system so as to be compatible with projected ASCI/VIEWS architectures.

  8. Estimating subsurface water volumes and transit times in Hokkaido river catchments, Japan, using high-accuracy tritium analysis

    Science.gov (United States)

    Gusyev, Maksym; Yamazaki, Yusuke; Morgenstern, Uwe; Stewart, Mike; Kashiwaya, Kazuhisa; Hirai, Yasuyuki; Kuribayashi, Daisuke; Sawano, Hisaya

    2015-04-01

    The goal of this study is to estimate subsurface water transit times and volumes in headwater catchments of Hokkaido, Japan, using the New Zealand high-accuracy tritium analysis technique. Transit time provides insights into the subsurface water storage and therefore provides a robust and quick approach to quantifying the subsurface groundwater volume. Our method is based on tritium measurements in river water. Tritium is a component of meteoric water, decays with a half-life of 12.32 years, and is inert in the subsurface after the water enters the groundwater system. Therefore, tritium is ideally suited for characterization of the catchment's responses and can provide information on mean water transit times up to 200 years. Only in recent years has it become possible to use tritium for dating of stream and river water, due to the fading impact of the bomb-tritium from thermo-nuclear weapons testing, and due to improved measurement accuracy for the extremely low natural tritium concentrations. Transit time of the water discharge is one of the most crucial parameters for understanding the response of catchments and estimating subsurface water volume. While many tritium transit time studies have been conducted in New Zealand, only a limited number of tritium studies have been conducted in Japan. In addition, the meteorological, orographic and geological conditions of Hokkaido Island are similar to those in parts of New Zealand, allowing for comparison between these regions. In 2014, three field trips were conducted in Hokkaido in June, July and October to sample river water at river gauging stations operated by the Ministry of Land, Infrastructure, Transport and Tourism (MLIT). These stations have altitudes between 36 m and 860 m MSL and drainage areas between 45 and 377 km2. Each sampled point is located upstream of MLIT dams, with hourly measurements of precipitation and river water levels enabling us to distinguish between the snow melt and baseflow contributions

  9. Diagnostic accuracy of GPs when using an early-intervention decision support system: a high-fidelity simulation

    Science.gov (United States)

    Kostopoulou, Olga; Porat, Talya; Corrigan, Derek; Mahmoud, Samhar; Delaney, Brendan C

    2017-01-01

    Background Observational and experimental studies of the diagnostic task have demonstrated the importance of the first hypotheses that come to mind for accurate diagnosis. A prototype decision support system (DSS) designed to support GPs’ first impressions has been integrated with a commercial electronic health record (EHR) system. Aim To evaluate the prototype DSS in a high-fidelity simulation. Design and setting Within-participant design: 34 GPs consulted with six standardised patients (actors) using their usual EHR. On a different day, GPs used the EHR with the integrated DSS to consult with six other patients, matched for difficulty and counterbalanced. Method Entering the reason for encounter triggered the DSS, which provided a patient-specific list of potential diagnoses, and supported coding of symptoms during the consultation. At each consultation, GPs recorded their diagnosis and management. At the end, they completed a usability questionnaire. The actors completed a satisfaction questionnaire after each consultation. Results There was an 8–9% absolute improvement in diagnostic accuracy when the DSS was used. This improvement was significant (odds ratio [OR] 1.41, 95% confidence interval [CI] = 1.13 to 1.77, PGPs coded significantly more data when using the DSS (mean 12.35 with the DSS versus 1.64 without), and were generally satisfied with its usability. Patient satisfaction ratings were the same for consultations with and without the DSS. Conclusion The DSS prototype was successfully employed in simulated consultations of high fidelity, with no measurable influences on patient satisfaction. The substantially increased data coding can operate as motivation for future DSS adoption. PMID:28137782

  10. High Accuracy Microwave Frequency Measurement Based on Single-Drive Dual-Parallel Mach-Zehnder Modulator

    DEFF Research Database (Denmark)

    Zhao, Ying; Deng, Lei; Pang, Xiaodan

    2011-01-01

    A novel approach for broadband microwave frequency measurement based on bias manipulation of a dual-parallel Mach-Zehnder modulator is proposed and experimentally demonstrated. A 10-3 relative error verifies a significant accuracy improvement by this method.......A novel approach for broadband microwave frequency measurement based on bias manipulation of a dual-parallel Mach-Zehnder modulator is proposed and experimentally demonstrated. A 10-3 relative error verifies a significant accuracy improvement by this method....

  11. An evaluation of the accuracy and precision of methane prediction equations for beef cattle fed high-forage and high-grain diets.

    Science.gov (United States)

    Escobar-Bahamondes, P; Oba, M; Beauchemin, K A

    2017-01-01

    The study determined the performance of equations to predict enteric methane (CH4) from beef cattle fed forage- and grain-based diets. Many equations are available to predict CH4 from beef cattle and the predictions vary substantially among equations. The aims were to (1) construct a database of CH4 emissions for beef cattle from published literature, and (2) identify the most precise and accurate extant CH4 prediction models for beef cattle fed diets varying in forage content. The database was comprised of treatment means of CH4 production from in vivo beef studies published from 2000 to 2015. Criteria to include data in the database were as follows: animal description, intakes, diet composition and CH4 production. In all, 54 published equations that predict CH4 production from diet composition were evaluated. Precision and accuracy of the equations were evaluated using the concordance correlation coefficient (r c ), root mean square prediction error (RMSPE), model efficiency and analysis of errors. Equations were ranked using a combined index of the various statistical assessments based on principal component analysis. The final database contained 53 studies and 207 treatment means that were divided into two data sets: diets containing ⩾400 g/kg dry matter (DM) forage (n=116) and diets containing ⩽200 g/kg DM forage (n=42). Diets containing between ⩽400 and ⩾200 g/kg DM forage were not included in the analysis because of their limited numbers (n=6). Outliers, treatment means where feed was fed restrictively and diets with CH4 mitigation additives were omitted (n=43). Using the high-forage dataset the best-fit equations were the International Panel on Climate Change Tier 2 method, 3 equations for steers that considered gross energy intake (GEI) and body weight and an equation that considered dry matter intake and starch:neutral detergent fiber with r c ranging from 0.60 to 0.73 and RMSPE from 35.6 to 45.9 g/day. For the high-grain diets, the 5 best

  12. Anti-aliasing filters for deriving high-accuracy DEMs from TLS data: A case study from Freeport, Texas

    Science.gov (United States)

    Xiong, Lin.; Wang, Guoquan; Wessel, Paul

    2017-03-01

    Terrestrial laser scanning (TLS), also known as ground-based Light Detection and Ranging (LiDAR), has been frequently applied to build bare-earth digital elevation models (DEMs) for high-accuracy geomorphology studies. The point clouds acquired from TLS often achieve a spatial resolution at fingerprint (e.g., 3 cm×3 cm) to handprint (e.g., 10 cm×10 cm) level. A downsampling process has to be applied to decimate the massive point clouds and obtain manageable DEMs. It is well known that downsampling can result in aliasing that causes different signal components to become indistinguishable when the signal is reconstructed from the datasets with a lower sampling rate. Conventional DEMs are mainly the results of upsampling of sparse elevation measurements from land surveying, satellite remote sensing, and aerial photography. As a consequence, the effects of aliasing caused by downsampling have not been fully investigated in the open literature of DEMs. This study aims to investigate the spatial aliasing problem of regridding dense TLS data. The TLS data collected from the beach and dune area near Freeport, Texas in the summer of 2015 are used for this study. The core idea of the anti-aliasing procedure is to apply a low-pass spatial filter prior to conducting downsampling. This article describes the successful use of a fourth-order Butterworth low-pass spatial filter employed in the Generic Mapping Tools (GMT) software package as an anti-aliasing filter. The filter can be applied as an isotropic filter with a single cutoff wavelength or as an anisotropic filter with two different cutoff wavelengths in the X and Y directions. The cutoff wavelength for the isotropic filter is recommended to be three times the grid size of the target DEM.

  13. Strategies for achieving high sequencing accuracy for low diversity samples and avoiding sample bleeding using illumina platform.

    Directory of Open Access Journals (Sweden)

    Abhishek Mitra

    Full Text Available Sequencing microRNA, reduced representation sequencing, Hi-C technology and any method requiring the use of in-house barcodes result in sequencing libraries with low initial sequence diversity. Sequencing such data on the Illumina platform typically produces low quality data due to the limitations of the Illumina cluster calling algorithm. Moreover, even in the case of diverse samples, these limitations are causing substantial inaccuracies in multiplexed sample assignment (sample bleeding. Such inaccuracies are unacceptable in clinical applications, and in some other fields (e.g. detection of rare variants. Here, we discuss how both problems with quality of low-diversity samples and sample bleeding are caused by incorrect detection of clusters on the flowcell during initial sequencing cycles. We propose simple software modifications (Long Template Protocol that overcome this problem. We present experimental results showing that our Long Template Protocol remarkably increases data quality for low diversity samples, as compared with the standard analysis protocol; it also substantially reduces sample bleeding for all samples. For comprehensiveness, we also discuss and compare experimental results from alternative approaches to sequencing low diversity samples. First, we discuss how the low diversity problem, if caused by barcodes, can be avoided altogether at the barcode design stage. Second and third, we present modified guidelines, which are more stringent than the manufacturer's, for mixing low diversity samples with diverse samples and lowering cluster density, which in our experience consistently produces high quality data from low diversity samples. Fourth and fifth, we present rescue strategies that can be applied when sequencing results in low quality data and when there is no more biological material available. In such cases, we propose that the flowcell be re-hybridized and sequenced again using our Long Template Protocol. Alternatively

  14. Eruptions of the last 2200 years at Vulcano and Vulcanello (Aeolian Islands, Italy) dated by high-accuracy archeomagnetism

    Science.gov (United States)

    Arrighi, Simone; Tanguy, Jean-Claude; Rosi, Mauro

    2006-12-01

    The recent eruptive history of the Vulcano island (Southern Italy) was investigated through the high-accuracy "large sample" archeomagnetic method (Tanguy, J.C., Le Goff, M., Principe, C., Arrighi, S., Chillemi, V., Paiotti, A., La Delfa, S., Patanè, G., 2003. Archeomagnetic dating of Mediterranean volcanics of the last 2100 years: validity and limits. Earth Planet. Sci. Lett. 211, 111-124; Tanguy, J.C., Principe, C., Arrighi, S., 2005. Comment on "Historical measurements of the Earth's magnetic field compared with remanence directions from lava flows in Italy over the last four centuries" by R. Lanza, A. Meloni, and E. Tema. Phys. Earth Planet. Interiors 152, 116-120; Arrighi, S., 2004. The large sample archeomagnetic method applied to Neapolitan volcanoes and Aeolian Islands. PhD Thesis. University of Pisa, Italy, pp. 1-186). Age determination is based upon directional geomagnetic variation reconstructed from historically dated lavas in Southern Italy, and from archeological sites in Western Europe (Gallet, Y., Genevey, A., Le Goff, M., 2002. Three millennia of directional variation of the Earth's magnetic field in Western Europe as revealed by archeological artefacts. Phys. Earth Planet. Interiors 131, 81-89) relocated to Sicily. Results in the present paper were obtained on 12 sites including 185 samples weighing 0.5-1 kg, distributed over the Vulcanello platform lavas and pyroclastic cones, and on the lava flows from the Fossa cone. It is shown that the Vulcanello platform was built by nearly continuous activity between AD 1000 and 1250, which is more than a millennium younger than believed until now from questionable interpretation of imprecise historical accounts. Most of the lavas from the Fossa cone, whose ages were rather hypothetical or known with a large uncertainty, have erupted within the same period. However, the last "Pietre Cotte" obsidian flow is confirmed to date from 1720 ± 30, in agreement with historical data (1739).

  15. High-accuracy absolute distance measurement by two-wavelength double heterodyne interferometry with variable synthetic wavelengths

    CERN Document Server

    Kuramoto, Yoshiyuki

    2014-01-01

    We present an absolute distance measurement interferometer based on a two wavelength interferometer and a variable synthetic wavelength technique. The wavelength scanning range was 12 GHz, realized with a phase accuracy of 1.0 m{\\lambda} by heterodyne detection at each measurement wavelength. This small wavelength scanning range enabled the use of distributed feedback laser diodes as an interferometer light source and a fast 20 ms wavelength scanning time by injection current control. We demonstrated a measurement range of up to 1.5 m and an accuracy better than 1.2 nm in comparison with a displacement measurement interferometer, corresponding to a relative accuracy of 10-9. In addition, we also proposed expanding the range of maximum measurement and compensation of refractive index of air for linear colliders.

  16. Patient and healthcare professional satisfaction with a new, high accuracy blood glucose meter with color range indicator and wireless connectivity.

    Science.gov (United States)

    Katz, Laurence B; Grady, Mike; Stewart, Lorna; Cameron, Hilary

    2016-07-01

    Accurate self-monitoring of blood glucose is a key component of effective self-management of glycemic control. The OneTouch VerioFlex(™) (OTVF) blood glucose monitoring system (BGMS) was evaluated for accuracy in a clinical setting. Patients also used OTVF for a 1-wk trial period and reported their level of satisfaction with meter features. In a separate study, healthcare professionals used an on-line simulator of the BGMS and answered questions about its potential utility to their patients. OTVF was accurate over a wide glucose range and met lay user and system accuracy blood glucose standards described in ISO15197:2013 as well as the accuracy requirements to fulfill US FDA expectations for 510(k) clearance of BGMS. Patients and healthcare professionals felt the features of OTVF, which has the capability to connect wirelessly to mobile devices and interact wirelessly with diabetes management software, could provide significant benefits to them or their patients.

  17. High-accuracy reference standards for two-photon absorption in the 680-1050 nm wavelength range.

    Science.gov (United States)

    de Reguardati, Sophie; Pahapill, Juri; Mikhailov, Alexander; Stepanenko, Yuriy; Rebane, Aleksander

    2016-04-18

    Degenerate two-photon absorption (2PA) of a series of organic fluorophores is measured using femtosecond fluorescence excitation method in the wavelength range, λ2PA = 680-1050 nm, and ~100 MHz pulse repetition rate. The function of relative 2PA spectral shape is obtained with estimated accuracy 5%, and the absolute 2PA cross section is measured at selected wavelengths with the accuracy 8%. Significant improvement of the accuracy is achieved by means of rigorous evaluation of the quadratic dependence of the fluorescence signal on the incident photon flux in the whole wavelength range, by comparing results obtained from two independent experiments, as well as due to meticulous evaluation of critical experimental parameters, including the excitation spatial- and temporal pulse shape, laser power and sample geometry. Application of the reference standards in nonlinear transmittance measurements is discussed.

  18. Context, accuracy, and level of inclusion of nature of science concepts in current high school physics textbooks

    Science.gov (United States)

    Alshamrani, Saeed Mohammed

    To improve K-12 students' images of the nature of science (NOS) through science textbooks, two issues must be addressed: (a) the level of NOS that ought to be included in science textbooks and (b) the treatment of this level in those textbooks. Science educators achieved a consensus level of agreement regarding what NOS aspects should be taught for K-12 science learners; however, there is a need for more clarification regarding the actual treatment of NOS in science textbooks. The purpose of this study is to investigate the NOS inclusion in high school physics textbooks. To be specific, this study examines the included NOS aspects, the frequency of NOS inclusion, the contexts exist for NOS inclusion, and the accuracy of NOS inclusion. This study utilized 12 science education studies to develop the Master Aspects of Nature of Science [MA-NOS] which includes 12 NOS aspects that ought to be included in K-12 science curriculum. The analyzed textbooks in this study are seven textbooks identified by The American Institute of Physics as the most widely used high school physics textbooks in the United States in 2005. These textbooks were used in teaching five academic levels: (a) Regular First-Year Physics, (b) Physics for Non-Science Students, (c) Honors Physics, (d) AP-B Physics, and (e) AP-C Physics. The researcher selected exclusively physics textbooks because physics is his main interest. To facilitate the content analysis of the selected textbooks, the study developed The Collection Data Coding Guide which includes six parts describing the MA-NOS aspects and the process of identifying and collecting data. For each NOS aspect, a description and one or more selected ideal indicators were provided to facilitate data collecting and judging the accuracy of NOS inclusion. This coding guide was reviewed for its content validity by two science educators who specialize in NOS. However, two types of reliability were conducted to identify the consistency of selecting NOS units

  19. Strategy for high-accuracy-and-precision retrieval of atmospheric methane from the mid-infrared FTIR network

    Directory of Open Access Journals (Sweden)

    R. Sussmann

    2011-09-01

    Full Text Available We present a strategy (MIR-GBM v1.0 for the retrieval of column-averaged dry-air mole fractions of methane (XCH4 with a precision <0.3% (1-σ diurnal variation, 7-min integration and a seasonal bias <0.14% from mid-infrared ground-based solar FTIR measurements of the Network for the Detection of Atmospheric Composition Change (NDACC, comprising 22 FTIR stations. This makes NDACC methane data useful for satellite validation and for the inversion of regional-scale sources and sinks in addition to long-term trend analysis. Such retrievals complement the high accuracy and precision near-infrared observations of the younger Total Carbon Column Observing Network (TCCON with time series dating back 15 years or so before TCCON operations began.

    MIR-GBM v1.0 is using HITRAN 2000 (including the 2001 update release and 3 spectral micro windows (2613.70–2615.40 cm−1, 2835.50–2835.80 cm−1, 2921.00–2921.60 cm−1. A first-order Tikhonov constraint is applied to the state vector given in units of per cent of volume mixing ratio. It is tuned to achieve minimum diurnal variation without damping seasonality. Final quality selection of the retrievals uses a threshold for the goodness of fit (χ2 < 1 as well as for the ratio of root-mean-square spectral noise and information content (<0.15%. Column-averaged dry-air mole fractions are calculated using the retrieved methane profiles and four-times-daily pressure-temperature-humidity profiles from National Center for Environmental Prediction (NCEP interpolated to the time of measurement.

    MIR-GBM v1.0 is the optimum of 24 tested retrieval strategies (8 different spectral micro-window selections, 3 spectroscopic line lists: HITRAN 2000, 2004, 2008. Dominant errors of the non-optimum retrieval strategies are systematic HDO/H2O-CH4 interference errors leading to a seasonal bias up to ≈5%. Therefore interference

  20. Assessment of the accuracy of PPP for very-high-frequency dynamic, satellite positioning and earthquake modeling

    Science.gov (United States)

    Moschas, F.; Avallone, A.; Moschonas, N.; Saltogianni, V.; Stiros, S.

    2012-04-01

    With the advent of various GPS/GNSS Point Positioning techniques, it became possible to model the dynamic displacement history of specific points during large and rather moderate earthquakes using satellite positioning, 1Hz and occasionally 10Hz sampling data. While there is evidence that the obtained data are precise, experience from monitoring of engineering structures like bridges, indicates that GPS/GNSS records are contaminated by coloured (mostly background noise) noise even in the cases of differential-type analysis of the satellite signals. This made the necessary the assessment of the results of different PPP processing using supervised learning techniques. Our work was based on a modification of an experiment first made to assess the potential of GPS to measure oscillations of civil engineering structures. A 10Hz GNSS antenna-receiver unit was mounted on the top of a vertical rod, fixed on the ground and forced to controlled oscillations. Oscillations were also recorded by a robotic theodolite and an accelerometer, and the whole experiment was video-recorded. A second 10Hz GNSS antenna-receiver unit was left on stable ground, in a nearby position. The rod was forced to semi-static motion (bending) and then was left to oscillate freely until still, and the whole movement was recorded by all sensors. GNSS data were analyzed both in kinematic mode and in PPP mode, using the GIPSY-OASIS II (http://gipsy-oasis.jpl.nasa.gov) (only GPS) and the PPP CRCS facility (GPS + GLONAS). Recorded PPP and differential kinematic processing coordinates (apparent displacements) were found to follow the real motion, but to be contaminated by a long-period noise. On the contrary, the short-period component of the apparent PPP displacements, obtained using high-pass filtering, were very much consistent with the real motion, with sub-mm mean deviation, though occasionally contaminated by clipping. The assessment of the very-high frequency GPS noise will provide useful information

  1. Transformation Model with Constraints for High-Accuracy of 2D-3D Building Registration in Aerial Imagery

    Directory of Open Access Journals (Sweden)

    Guoqing Zhou

    2016-06-01

    Full Text Available This paper proposes a novel rigorous transformation model for 2D-3D registration to address the difficult problem of obtaining a sufficient number of well-distributed ground control points (GCPs in urban areas with tall buildings. The proposed model applies two types of geometric constraints, co-planarity and perpendicularity, to the conventional photogrammetric collinearity model. Both types of geometric information are directly obtained from geometric building structures, with which the geometric constraints are automatically created and combined into the conventional transformation model. A test field located in downtown Denver, Colorado, is used to evaluate the accuracy and reliability of the proposed method. The comparison analysis of the accuracy achieved by the proposed method and the conventional method is conducted. Experimental results demonstrated that: (1 the theoretical accuracy of the solved registration parameters can reach 0.47 pixels, whereas the other methods reach only 1.23 and 1.09 pixels; (2 the RMS values of 2D-3D registration achieved by the proposed model are only two pixels along the x and y directions, much smaller than the RMS values of the conventional model, which are approximately 10 pixels along the x and y directions. These results demonstrate that the proposed method is able to significantly improve the accuracy of 2D-3D registration with much fewer GCPs in urban areas with tall buildings.

  2. Accuracy and initial stability of open- and closed-wedge high tibial osteotomy: a cadaveric RSA study.

    NARCIS (Netherlands)

    Gaasbeek, R.D.A.; Welsing, R.T.C.; Verdonschot, N.J.J.; Rijnberg, W.J.; Loon, C.J.M. van; Kampen, A. van

    2005-01-01

    We analyzed the difference in angle-correction accuracy and initial stability between open-wedge (OWO) and closed-wedge tibial valgus osteotomy (CWO). Five fresh-frozen pairs of human cadaver lower limbs were used; their bone mineral density (BMD) was measured with DEXA and a planned 7 degrees valgu

  3. Continuous assessment of land mapping accuracy at High Resolution from global networks of atmospheric and field observatories -concept and demonstration

    Science.gov (United States)

    Sicard, Pierre; Martin-lauzer, François-regis

    2017-04-01

    In the context of global climate change and adjustment/resilience policies' design and implementation, there is a need not only i. for environmental monitoring, e.g. through a range of Earth Observations (EO) land "products" but ii. for a precise assessment of uncertainties of the aforesaid information that feed environmental decision-making (to be introduced in the EO metadata) and also iii. for a perfect handing of the thresholds which help translate "environment tolerance limits" to match detected EO changes through ecosystem modelling. Uncertainties' insight means precision and accuracy's knowledge and subsequent ability of setting thresholds for change detection systems. Traditionally, the validation of satellite-derived products has taken the form of intensive field campaigns to sanction the introduction of data processors in Payload Data Ground Segments chains. It is marred by logistical challenges and cost issues, reason why it is complemented by specific surveys at ground-based monitoring sites which can provide near-continuous observations at a high temporal resolution (e.g. RadCalNet). Unfortunately, most of the ground-level monitoring sites, in the number of 100th or 1000th, which are part of wider observation networks (e.g. FLUXNET, NEON, IMAGINES) mainly monitor the state of the atmosphere and the radiation exchange at the surface, which are different to the products derived from EO data. In addition they are "point-based" compared to the EO cover to be obtained from Sentinel-2 or Sentinel-3. Yet, data from these networks, processed by spatial extrapolation models, are well-suited to the bottom-up approach and relevant to the validation of vegetation parameters' consistency (e.g. leaf area index, fraction of absorbed photosynthetically active radiation). Consistency means minimal errors on spatial and temporal gradients of EO products. Test of the procedure for land-cover products' consistency assessment with field measurements delivered by worldwide

  4. Calibration for Relative Interior Orientation Relationship and Band-to-band Registration with High Accuracy of ZY-3 Multi-spectral Image

    Directory of Open Access Journals (Sweden)

    LI Qijun

    2016-06-01

    Full Text Available Using high accuracy match points extracted between the multi-spectral images that obtained at the same time,a position model of the CCD chips of the ZY-3 multi-spectral camera was proposed. Relative interior orientation relationship parameters were calculated and accurate band-to-band automatic registration of ZY-3 multi-spectral image was achieved based on the position model. The experimental result indicates that the band-to-band automatic registration accuracy of ZY-3 multi-spectral image is better than 0.3 pixels with the proposed method.

  5. Performing elemental microanalysis with high accuracy and high precision by scanning electron microscopy/silicon drift detector energy-dispersive X-ray spectrometry (SEM/SDD-EDS).

    Science.gov (United States)

    Newbury, Dale E; Ritchie, Nicholas W M

    Electron-excited X-ray microanalysis performed in the scanning electron microscope with energy-dispersive X-ray spectrometry (EDS) is a core technique for characterization of the microstructure of materials. The recent advances in EDS performance with the silicon drift detector (SDD) enable accuracy and precision equivalent to that of the high spectral resolution wavelength-dispersive spectrometer employed on the electron probe microanalyzer platform. SDD-EDS throughput, resolution, and stability provide practical operating conditions for measurement of high-count spectra that form the basis for peak fitting procedures that recover the characteristic peak intensities even for elemental combination where severe peak overlaps occur, such PbS, MoS2, BaTiO3, SrWO4, and WSi2. Accurate analyses are also demonstrated for interferences involving large concentration ratios: a major constituent on a minor constituent (Ba at 0.4299 mass fraction on Ti at 0.0180) and a major constituent on a trace constituent (Ba at 0.2194 on Ce at 0.00407; Si at 0.1145 on Ta at 0.0041). Accurate analyses of low atomic number elements, C, N, O, and F, are demonstrated. Measurement of trace constituents with limits of detection below 0.001 mass fraction (1000 ppm) is possible within a practical measurement time of 500 s.

  6. Research on the classification result and accuracy of building windows in high resolution satellite images: take the typical rural buildings in Guangxi, China, as an example

    Science.gov (United States)

    Li, Baishou; Gao, Yujiu

    2015-12-01

    The information extracted from the high spatial resolution remote sensing images has become one of the important data sources of the GIS large scale spatial database updating. The realization of the building information monitoring using the high resolution remote sensing, building small scale information extracting and its quality analyzing has become an important precondition for the applying of the high-resolution satellite image information, because of the large amount of regional high spatial resolution satellite image data. In this paper, a clustering segmentation classification evaluation method for the high resolution satellite images of the typical rural buildings is proposed based on the traditional KMeans clustering algorithm. The factors of separability and building density were used for describing image classification characteristics of clustering window. The sensitivity of the factors influenced the clustering result was studied from the perspective of the separability between high image itself target and background spectrum. This study showed that the number of the sample contents is the important influencing factor to the clustering accuracy and performance, the pixel ratio of the objects in images and the separation factor can be used to determine the specific impact of cluster-window subsets on the clustering accuracy, and the count of window target pixels (Nw) does not alone affect clustering accuracy. The result can provide effective research reference for the quality assessment of the segmentation and classification of high spatial resolution remote sensing images.

  7. High-accuracy measurement of the {sup 87}Rb ground-state hyperfine splitting in an atomic fountain

    Energy Technology Data Exchange (ETDEWEB)

    Bize, S.; Sortais, Y.; Clairon, A. [Observatoire de Paris (France). BNM-LPTF; Santos, M.S. [Inst. de Fisica de Sao Carlos-USP, Dept. de Fisica e Ciencia dos Materiais, Sao Carlos (Brazil); Mandache, C. [Inst. National de Fizica Laserilor, Plasmei si Radiatiei, Bucuresti, Magurele (Romania); Salomon, C. [Lab. Kastler Brossel, Ecole Normale Superieure, Paris (France)

    1999-03-01

    We describe the operation of a laser-cooled rubidium {sup 87}Rb frequency standard. We present a new measurement of the {sup 87}Rb hyperfine frequency with a 1.3 x 10{sup -14} relative accuracy, by comparison with a Cs fountain primary standard. The measured {sup 87}Rb ground-state hyperfine splitting is {nu}{sup {sub 87}}{sub Rb} = 6 834 682 610.90429(9) Hz. This value differs from previously published values (see Essen L., Hope E. G. and Sutcliffe D. (1961); Penselin S., Moran T., Cohen W. and Winkler G. (1962); Arditi M. and Cerez P. (1972)) by about 2-3 Hz and is 10{sup 4} times more accurate. Because of the low collisional shift in {sup 87}Rb, future improvements may lead to a stability of 1 x 10{sup -14}{tau}{sup -1/2} and a relative accuracy in the 10{sup -17} range. (orig.) 23 refs.

  8. Geometric Accuracy Investigations of SEVIRI High Resolution Visible (HRV Level 1.5 Imagery

    Directory of Open Access Journals (Sweden)

    Sultan Kocaman Aksakal

    2013-05-01

    Full Text Available GCOS (Global Climate Observing System is a long-term program for monitoring the climate, detecting the changes, and assessing their impacts. Remote sensing techniques are being increasingly used for climate-related measurements. Imagery of the SEVIRI instrument on board of the European geostationary satellites Meteosat-8 and Meteosat-9 are often used for the estimation of essential climate variables. In a joint project between the Swiss GCOS Office and ETH Zurich, geometric accuracy and temporal stability of 1-km resolution HRV channel imagery of SEVIRI have been evaluated over Switzerland. A set of tools and algorithms has been developed for the investigations. Statistical analysis and blunder detection have been integrated in the process for robust evaluation. The relative accuracy is evaluated by tracking large numbers of feature points in consecutive HRV images taken at 15-minute intervals. For the absolute accuracy evaluation, lakes in Switzerland and surroundings are used as reference. 20 lakes digitized from Landsat orthophotos are transformed into HRV images and matched via 2D translation terms at sub-pixel level. The algorithms are tested using HRV images taken on 24 days in 2008 (2 days per month. The results show that 2D shifts that are up to 8 pixels are present both in relative and absolute terms.

  9. High degree of accuracy of a novel image-free handheld robot for unicondylar knee arthroplasty in a cadaveric study.

    Science.gov (United States)

    Lonner, Jess H; Smith, Julie R; Picard, Frederic; Hamlin, Brian; Rowe, Philip J; Riches, Philip E

    2015-01-01

    Surgical robotics has been shown to improve the accuracy of bone preparation and soft tissue balance in unicondylar knee arthroplasty (UKA). However, although extensive data have emerged with regard to a CT scan-based haptically constrained robotic arm, little is known about the accuracy of a newer alternative, an imageless robotic system. We assessed the accuracy of a novel imageless semiautonomous freehand robotic sculpting system in performing bone resection and preparation in UKA using cadaveric specimens. In this controlled study, we compared the planned and final implant placement in 25 cadaveric specimens undergoing UKA using the new tool. A quantitative analysis was performed to determine the translational, angular, and rotational differences between the planned and achieved positions of the implants. The femoral implant rotational mean error was 1.04° to 1.88° and mean translational error was 0.72 to 1.29 mm across the three planes. The tibial implant rotational mean error was 1.48° to 1.98° and the mean translational error was 0.79 to 1.27 mm across the three planes. The image-free robotic sculpting tool achieved accurate implementation of the surgical plan with small errors in implant placement. The next step will be to determine whether accurate implant placement translates into a clinical and functional benefit for the patient.

  10. High-accuracy topographical information extraction based on fusion of ASTER stereo-data and ICESat/GLAS data in Antarctica

    Institute of Scientific and Technical Information of China (English)

    Wang DongChen; SHEN Qiang; XU Ying; CHEN Gang

    2009-01-01

    In order to better support Antarctic Inland ice sheet expedition from Zhongshan Station to Dome A, the topographic data are necessary. At present, although the entire Antarctic DEM provided by RAMP (Ra-daraat Antarctic Mapping Project) was estimated at the highest horizontal (spatial) resolution of about 200 m, the real horizontal resolution of the DEM varies from place to place depending on the density and scale of the original source data. For ice shelves and the inland ice sheet, the horizontal resolution is about 5 km; the vertical accuracy is estimated to be ±50 m in interior East Antarctic ice sheet and away from the mountain ranges. Therefore, more accurate topographic data are unavailable in Antarc-tica. In order to meet the requirements of high-accuracy topographic information for further researches, this paper mainly addresses a fusion study of ASTER stereo pairs and ICESat/GLAS altimetry data for extraction of high-accuracy DEM in East Antarctica, based on the high horizontal resolution (15 m) of ASTER and vertical accuracy (13.8 cm) of ICESat/GLAS. First, some altimetry data were selected as vertical control points to reduce errors of image correlation matching during the extraction of ASTER-based DEM. Second, ice sheet altimetry data derived from ICESat were used to generate DEM ranging from 75° to 81°S because existing ASTER data do not cover this area and high density of the coverage of ICESat altimetry data. Finally, the DEM in coverage of the expedition route was produced. The analysis of result reveals that the DEM accuracy is improved significantly. The absolute vertical accuracy of DEM is higher than 15 m in some cases and higher than 30 m for all the areas along the expedition route except from the 009-001 scene; the interior accuracy is higher than 15 m and higher than 7 m in some cases. It can meet the requirements of topographic map at 1 : 50000 scale, which is an economic and advantageous method to produce the topographic products.

  11. Cost-effective improvements of a rotating platform by integration of a high-accuracy inclinometer and encoders for attitude evaluation

    Science.gov (United States)

    Wen, Chenyang; He, Shengyang; Bu, Changgen; Hu, Peida

    2017-01-01

    Attitude heading reference systems (AHRSs) based on micro-electromechanical system (MEMS) inertial sensors are widely used because of their low cost, light weight, and low power. However, low-cost AHRSs suffer from large inertial sensor errors. Therefore, experimental performance evaluation of MEMS-based AHRSs after system implementation is necessary. High-accuracy turntables can be used to verify the performance of MEMS-based AHRSs indoors, but they are expensive and unsuitable for outdoor tests. This study developed a low-cost two-axis rotating platform for indoor and outdoor attitude determination. A high-accuracy inclinometer and encoders were integrated into the platform to improve the achievable attitude test accuracy. An attitude error compensation method was proposed to calibrate the initial attitude errors caused by the movements and misalignment angles of the platform. The proposed attitude error determination method was examined through rotating experiments, which showed that the standard deviations of the pitch and roll errors were 0.050° and 0.090°, respectively. The pitch and roll errors both decreased to 0.024° when the proposed attitude error determination method was used. This decrease validates the effectiveness of the compensation method. Experimental results demonstrated that the integration of the inclinometer and encoders improved the performance of the low-cost, two-axis, rotating platform in terms of attitude accuracy.

  12. Very high precision and accuracy analysis of triple isotopic ratios of water. A critical instrumentation comparison study.

    Science.gov (United States)

    Gkinis, Vasileios; Holme, Christian; Morris, Valerie; Thayer, Abigail Grace; Vaughn, Bruce; Kjaer, Helle Astrid; Vallelonga, Paul; Simonsen, Marius; Jensen, Camilla Marie; Svensson, Anders; Maffrezzoli, Niccolo; Vinther, Bo; Dallmayr, Remi

    2017-04-01

    We present a performance comparison study between two state of the art Cavity Ring Down Spectrometers (Picarro L2310-i, L2140-i). The comparison took place during the Continuous Flow Analysis (CFA) campaign for the measurement of the Renland ice core, over a period of three months. Instant and complete vaporisation of the ice core melt stream, as well as of in-house water reference materials is achieved by accurate control of microflows of liquid into a homemade calibration system by following simple principles of the Hagen-Poiseuille law. Both instruments share the same vaporisation unit in a configuration that minimises sample preparation discrepancies between the two analyses. We describe our SMOW-SLAP calibration and measurement protocols for such a CFA application and present quality control metrics acquired during the full period of the campaign on a daily basis. The results indicate an unprecedented performance for all 3 isotopic ratios (δ2H, δ17O, δ18O ) in terms of precision, accuracy and resolution. We also comment on the precision and accuracy of the second order excess parameters of HD16O and H217O over H218O (Dxs, Δ17O ). To our knowledge these are the first reported CFA measurements at this level of precision and accuracy for all three isotopic ratios. Differences on the performance of the two instruments are carefully assessed during the measurement and reported here. Our quality control protocols extend to the area of low water mixing ratios, a regime in which often atmospheric vapour measurements take place and Cavity Ring Down Analysers show a poorer performance due to the lower signal to noise ratios. We address such issues and propose calibration protocols from which water vapour isotopic analyses can benefit from.

  13. Mildronate (Meldonium) in professional sports - monitoring doping control urine samples using hydrophilic interaction liquid chromatography - high resolution/high accuracy mass spectrometry.

    Science.gov (United States)

    Görgens, Christian; Guddat, Sven; Dib, Josef; Geyer, Hans; Schänzer, Wilhelm; Thevis, Mario

    2015-01-01

    To date, substances such as Mildronate (Meldonium) are not on the radar of anti-doping laboratories as the compound is not explicitly classified as prohibited. However, the anti-ischemic drug Mildronate demonstrates an increase in endurance performance of athletes, improved rehabilitation after exercise, protection against stress, and enhanced activations of central nervous system (CNS) functions. In the present study, the existing evidence of Mildronate's usage in sport, which is arguably not (exclusively) based on medicinal reasons, is corroborated by unequivocal analytical data allowing the estimation of the prevalence and extent of misuse in professional sports. Such data are vital to support decision-making processes, particularly regarding the ban on drugs in sport. Due to the growing body of evidence (black market products and athlete statements) concerning its misuse in sport, adequate test methods for the reliable identification of Mildronate are required, especially since the substance has been added to the 2015 World Anti-Doping Agency (WADA) monitoring program. In the present study, two approaches were established using an in-house synthesized labelled internal standard (Mildronate-D3 ). One aimed at the implementation of the analyte into routine doping control screening methods to enable its monitoring at the lowest possible additional workload for the laboratory, and another that is appropriate for the peculiar specifics of the analyte, allowing the unequivocal confirmation of findings using hydrophilic interaction liquid chromatography-high resolution/high accuracy mass spectrometry (HILIC-HRMS). Here, according to applicable regulations in sports drug testing, a full qualitative validation was conducted. The assay demonstrated good specificity, robustness (rRT=0.3%), precision (intra-day: 7.0-8.4%; inter-day: 9.9-12.9%), excellent linearity (R>0.99) and an adequate lower limit of detection (<10 ng/mL).

  14. Accurate mass measurements of very short-lived nuclei. Prerequisites for high-accuracy investigations of superallowed {beta}-decays

    Energy Technology Data Exchange (ETDEWEB)

    Herfurth, F.; Kellerbauer, A.; Sauvan, E. [CERN, 1211 Geneva 23 (Switzerland); Ames, F.; Engels, O. [Sektion Physik, Ludwig-Maximilians-Universitaet Muenchen, 85748 Garching (Germany); Audi, G.; Lunney, D. [CSNSM-IN2P3-CNRS, 91405 Orsay Campus (France); Beck, D.; Blaum, K.; Kluge, H.J.; Scheidenberger, C.; Sikler, G.; Weber, C. [GSI, Planckstrasse 1, 64291 Darmstadt (Germany); Bollen, G.; Schwarz, S. [NSCL, Michigan State University, East Lansing MI 48824-1321 (United States); Moore, R.B. [Department of Physics, McGill University, Montreal (Quebec) H3A 2T8 (Canada); Oinonen, M. [Helsinki Institute of Physics, University of Helsinki, P.O. Box 9, 00014 Helsinki (Finland)

    2002-10-01

    Mass measurements of {sup 34}Ar, {sup 73-78}Kr, and {sup 74,76}Rb were performed with the Penning-trap mass spectrometer ISOLTRAP. Very accurate Q{sub EC}-values are needed for the investigations of the Ft-value of 0{sup +} {yields} 0{sup +} nuclear {beta}-decays used to test the standard model predictions for weak interactions. The necessary accuracy on the Q{sub EC}-value requires the mass of mother and daughter nuclei to be measured with {delta}m/m {<=} 3{sup .}10 {sup -8}. For most of the measured nuclides presented here this has been reached. The {sup 34}Ar mass has been measured with a relative accuracy of 1.1 .10{sup -8}. The Q {sub EC}-value of the {sup 34}Ar 0 {sup +} {yields} 0 {sup +} decay can now be determined with an uncertainty of about 0.01%. Furthermore, {sup 74}Rb is the shortest-lived nuclide ever investigated in a Penning trap. (orig.)

  15. 4-Dimensionally Guided 3-Dimensional Color-Doppler Ultrasonography Quantifies Carotid Artery Stenosis With High Reproducibility and Accuracy.

    Science.gov (United States)

    Macharzina, Roland Richard; Kocher, Sascha; Messé, Steven R; Rutkowski, Thomas; Hoffmann, Fabian; Vogt, Matthias; Vach, Werner; Fan, Nian; Rastan, Aljoscha; Neumann, Franz-Josef; Zeller, Thomas

    2017-07-13

    The purpose was to analyze the agreement and binary accuracy of the degree of internal carotid artery stenosis (ICAS) as determined by 4-dimensionally (4D) real-time gray-scale guided 3-dimensional (3D) color-Doppler ultrasonography (3DC-US) (4D/3DC-US) compared with catheter angiography (CA) and duplex ultrasonography (DUS). This study hypothesized that 4D/3DC-US is noninferior to CA and DUS in grading ICAS in selected patients. Clinical stratification in patients with ICAS largely depends on a patient's symptomatic status and the degree of stenosis. Screening with 4D/3DC-US was prospectively performed in 93 study patients (with 122 ICASs), thus yielding 80 patients for analysis (with 103 ICASs) after excluding patients with insufficient image quality, previous revascularization, and contraindications to CA. The ultrasound examination (10 MHz) consisted of consensus conform DUS examination and independent real-time 4D-guided gray-scale views for orientation followed by static 3DC-US NASCET (North American Symptomatic Carotid Endarterectomy Trial) percent stenosis quantification using off-line multiplanar rendering. Multiplanar selective CA of the same ICASs was quantified with dedicated software in a blinded fashion. Quantitative CA of 103 stenoses with a mean degree of 65 ± 17% was compared with 4D/3DC-US, with a resulting concordance correlation coefficient of 0.89 and a standard deviation of differences (SDD) of 8.1% at a bias of +1.7%. Binary 50% and 70% stenosis detection with 4D/3DC-US revealed a sensitivity of 97% and 87%, respectively, and a specificity of 92% and 84%, respectively. Interobserver SDD for CA of 52 stenoses (7.2%) did not differ from SDD for 4D/3DC-US and CA (p = 0.274). Accuracy of 50% stenosis detection by 4D/3DC-US was tendentially higher compared with DUS (96% vs. 91%). The 4D/3DC-US method provides reliable and accurate stenosis quantification and binary classification with good diagnostic accuracy compared with CA and DUS. Copyright

  16. Drainage borehole with high directional accuracy using directional drilling equipment modified for the mining industry; Wasserloesungsbohrung mit hoher Zielgenauigkeit unter Einsatz einer fuer den Bergbau modifizierten Richtbohrausruestung

    Energy Technology Data Exchange (ETDEWEB)

    Wilkening, Matthias [MICON Drilling GmbH, Nienhagen (Germany)

    2009-01-29

    To carry out a drainage project it was necessary to divert water from an abandoned mine and direct it to an existing drainage system. To ensure that the borehole required for this purpose terminates accurately in a roadway a borehole meeting a high requirement on constant drilling and directional accuracy was necessary. Hence a combination of existing drilling equipment and directional drilling specifically adapted to these requirements was used. (orig.)

  17. Reader Accuracy and Confidence in Diagnosing Diffuse Lung Disease on High-Resolution Computed Tomography of the Lungs: Impact of Sampling Frequency

    Energy Technology Data Exchange (ETDEWEB)

    Sundaram, B.; Gross, B.H.; Oh, E.; Mueller, N.; Myles, J.D.; Kazerooni, E.A. (Dept. of Radiology, Michigan Institute for Clinical Health Research, Univ. of Michigan Health System, Ann Arbor, Michigan (United States))

    2008-10-15

    Background: The accuracy of the number of high-resolution computed tomography (HRCT) images necessary to diagnose diffuse lung disease (DLD) is not well established. Purpose: To evaluate the impact of HRCT sampling frequency on reader confidence and accuracy for diagnosing DLD. Material and Methods: HRCT images of 100 consecutive patients with proven DLD were reviewed. They were: 48 usual interstitial pneumonia, 22 sarcoidosis, six hypersensitivity pneumonitis, five each of desquamative interstitial pneumonitis, eosinophilic granulomatosis, and lymphangioleiomyomatosis, and nine others. Inspiratory images at 1-cm increments throughout the lungs and three specified levels formed complete and limited examinations. In random order, three experts (readers 1, 2, and 3) ranked their top three diagnoses and rated confidence for their top diagnosis, independently and blinded to clinical information. Results: Using the complete versus limited examinations for correct first-choice diagnosis, accuracy for reader 1 (R1) was 81% versus 80%, respectively, for reader 2 (R2) 70% versus 70%, and for reader 3 (R3) 64% versus 59%. Reader accuracy within their top three choices for complete versus limited examinations was: R1 91% versus 91% of cases, respectively, R2 84% versus 83%, and R3 79% versus 72% of cases. No statistically significant differences were found between the diagnosis methods (P=0.28 for first diagnosis and P=0.17 for top three choices). The confidence intervals for individual raters showed considerable overlap, and the point estimates are almost identical. The mean interreader agreement for complete versus limited HRCT for both top and top three diagnoses were the same (moderate and fair, respectively). The mean intrareader agreement between complete and limited HRCT for top and top three diagnoses were substantial and moderate, respectively. Conclusion: Overall reader accuracy and confidence in diagnosis did not significantly differ when fewer or more HRCT images

  18. Expanding analytical possibilities concerning the detection of stanozolol misuse by means of high resolution/high accuracy mass spectrometric detection of stanozolol glucuronides in human sports drug testing.

    Science.gov (United States)

    Schänzer, Wilhelm; Guddat, Sven; Thomas, Andreas; Opfermann, Georg; Geyer, Hans; Thevis, Mario

    2013-01-01

    Anabolic-androgenic steroids (AAS) represent one of the most frequently detected classes of prohibited substances in doping controls. Due to their long-lasting beneficial effects on athletic performance, utmost retrospectivity via urine analysis is desirable and accomplished by targeting long-term metabolites of the respective drugs. In case of stanozolol, a substantial variety of metabolites has enabled the identification of numerous adverse analytical findings in the past, and recent studies concerning complementary phase-I and phase-II metabolites has further expanded the windows of opportunity for detecting the abuse of stanozolol. In this study, the utility of liquid chromatography-high resolution/high accuracy (tandem) mass spectrometry (LC-MS/MS) for the detection of 3'-OH-stanozolol glucuronide in sports drug testing is presented and the identification of two additional and so far unreported metabolites is shown. The structures of the complementary glucuronic acid conjugates were attributed to stanozolol-N-glucuronide and 17-epistanozolol-N-glucuronide. By means of chemical synthesis, stanozolol-N-glucuronide was prepared and used to corroborate the suggested structures. The 3'-OH-stanozolol glucuronide and the newly identified target compounds were implemented into routine sports drug test assays consisting of direct injection LC-MS/MS or solid-phase extraction (SPE) followed by LC-MS/MS. A considerably expanded detection window for stanozolol abuse was demonstrated compared to the use of conventional phase-I metabolites and methodologies based on, for example, low resolution LC-MS/MS or gas chromatography-tandem mass spectrometry (GC-MS/MS). The commercial availability of 3'-OH-stanozolol glucuronide has been of great value for confirmatory purposes, and 17-epistanozolol-N-glucuronide was found to be a favourable long-term metabolite for doping controls as it was observed up to 28 days post-administration of the drug. Applying the established

  19. 高动态GPS单点定位的精度分析%Analysis of High Dynamic GPS Point Positioning Accuracy

    Institute of Scientific and Technical Information of China (English)

    白帆

    2013-01-01

      在工作中,我们经常采用GPS用户台对空中高速运动目标进跟踪测量,而普通GPS算法无法给出高动态单点定位的定位精度。运用最小二乘原理解算动态GPS用户台的定位方程,并对其进行精度评定能够得到动态单点定位精度,且简单、实用,具有很高的实际应用价值。%During operation, GPS user station is generally used to track and measure air high-speed moving-targets. The positioning accuracy of high dynamic point positioning can’t be achieved depending only on common GPS algorithm. Based on the principle of least square method, the positioning equation of dynamic GPS user station is solved. After the accuracy assessment, dynamic point positioning accuracy is obtained. The simple and practical method has a bright prospect of application.

  20. Magnetic resonance imaging for preoperative staging of rectal cancer in clinical practice: high accuracy in predicting circumferential margin with clinical benefit.

    Science.gov (United States)

    Videhult, P; Smedh, K; Lundin, P; Kraaz, W

    2007-06-01

    The aims were to determine agreement between staging of rectal cancer made by magnetic resonance imaging (MRI) and histopathological examination and the influence of MRI on choice of radiotherapy (RT) and surgical procedure. In this retrospective audit, preoperative MRI was performed on 91 patients who underwent bowel resection, with 93% having total mesorectal excision. Tumour stage according to mural penetration, nodal status and circumferential resection margin (mCRM) involvement was assessed and compared with histopathology. Five radiologists interpreted the images. Overall agreement between MRI and histopathology for T stage was 66%. The greatest difficulty was in distinguishing between T1, T2 and minimal T3 tumours. The accuracy for mCRM (MRI) was 86% (78/91),with an interobserver variation between 80% and 100%. In the 13 cases with no agreement between mCRM and pCRM (pathological), seven had long-term RT and nine en bloc resections, indicating that the margins initially were involved with an even higher accuracy for mCRM. Preoperative short-term RT was routine, but based on MRI findings, choice of RT was affected in 29 cases (32%); 17 patients had no RT and 12 long-term RT. The surgical procedure was affected in 17 cases (19%) with planned perirectal en bloc resections in all. CRM was involved (CRM with high accuracy in rectal cancer. MRI could be used as a clinical guidance with high reliability as indicated by the low figures of histopathologically involved CRM.

  1. High-accuracy diagnostic tool for electron cloud observation in the LHC based on synchronous phase measurements

    CERN Document Server

    Esteban Müller, J F; Shaposhnikova, E; Valuch, D; Mastoridis, T

    2014-01-01

    Electron cloud effects such as heat load in the cryogenic system, pressure rise and beam instabilities are among the main limitations for the LHC operation with 25 ns spaced bunches. A new observation tool was developed to monitor the e-cloud activity and has been successfully used in the LHC during Run 1 (2010-2012). The power loss of each bunch due to the e-cloud can be estimated using very precise bunch-by-bunch measurement of the synchronous phase shift. In order to achieve the required accuracy, corrections for reflection in the cables and some systematic errors need to be applied followed by a post-processing of the measurements. Results clearly show the e-cloud build-up along the bunch trains and its evolution during each LHC fill as well as from fill to fill. Measurements during the 2012 LHC scrubbing run reveal a progressive reduction in the e-cloud activity and therefore a decrease in the secondary electron yield (SEY). The total beam power loss can be computed as a sum of the contributions from all...

  2. Hermite finite elements for high accuracy electromagnetic field calculations: A case study of homogeneous and inhomogeneous waveguides

    Science.gov (United States)

    Boucher, C. R.; Li, Zehao; Ahheng, C. I.; Albrecht, J. D.; Ram-Mohan, L. R.

    2016-04-01

    Maxwell's vector field equations and their numerical solution represent significant challenges for physical domains with complex geometries. There are several limitations in the presently prevalent approaches to the calculation of field distributions in physical domains, in particular, with the vector finite elements. In order to quantify and resolve issues, we consider the modeling of the field equations for the prototypical examples of waveguides. We employ the finite element method with a new set of Hermite interpolation polynomials derived recently by us using group theoretic considerations. We show that (i) the approach presented here yields better accuracy by several orders of magnitude, with a smoother representation of fields than the vector finite elements for waveguide calculations. (ii) This method does not generate any spurious solutions that plague Lagrange finite elements, even though the C1 -continuous Hermite polynomials are also scalar in nature. (iii) We present solutions for propagating modes in inhomogeneous waveguides satisfying dispersion relations that can be derived directly, and investigate their behavior as the ratio of dielectric constants is varied both theoretically and numerically. Additional comparisons and advantages of the proposed method are detailed in this article. The Hermite interpolation polynomials are shown to provide a robust, accurate, and efficient means of solving Maxwell's equations in a variety of media, potentially offering a computationally inexpensive means of designing devices for optoelectronics and plasmonics of increasing complexity.

  3. Measurement of Nuclear Reaction Q-values with High Accuracy: 7Li(p, n)7Be

    Science.gov (United States)

    White, R. E.; Barker, P. H.; Lovelock, D. M. J.

    1985-01-01

    A technique is described for the measurement of nuclear reaction Q-values with an accuracy of a few parts in 105, in which the ultimate reference is a one-volt standard. As a test of the technique the accurately known threshold energy of the 7Li(p, n)7Be reaction, 1880.51 +/- 0.08 keV, has been remeasured. The value found using the present technique is 1880.443 +/- 0.020 keV, in good agreement with previous values. An attempt to see evidence for atomic excitation effects in the 27A1(p,n)27Si reaction is also discussed. This yielded a new value of 5803.73 +/- 0.12 keV for the threshold of this reaction, again in a good agreement with, but more accurate than, previous values. Further test measurements are summarized. The main application of the technique, in measurements related to the theory of weak interactions, is discussed briefly and the results obtained to date are presented.

  4. Effect of marital status on death rates. Part 1: High accuracy exploration of the Farr-Bertillon effect

    CERN Document Server

    Richmond, Peter

    2015-01-01

    The Farr-Bertillon law says that for all age-groups the death rate of married people is lower than the death rate of people who are not married (i.e. single, widowed or divorced). Although this law has been known for over 150 years, it has never been established with great accuracy. This even let some authors argue that it was a statistical artefact. It is true that the data must be selected and analyzed with great care, especially for age groups of small size such as widowers under 25. The observations reported in this paper were selected and designed in the same way as experiments in physics, that is to say with the objective of minimizing the error bars for all age-groups. It will be seen that data appropriate for mid-age groups may be unsuitable for young age groups and vice versa. The investigation led to the following results. (1) The FB effect is basically the same for men and women, except that on average it is about 20\\% stronger for men. (2) There is a marked difference between single or divorced pe...

  5. Effect of marital status on death rates. Part 1: High accuracy exploration of the Farr-Bertillon effect

    Science.gov (United States)

    Richmond, Peter; Roehner, Bertrand M.

    2016-05-01

    The Farr-Bertillon law says that for all age-groups the death rate of married people is lower than the death rate of people who are not married (i.e. single, widowed or divorced). Although this law has been known for over 150 years, it has never been established with well-controlled accuracy (e.g. error bars). This even let some authors argue that it was a statistical artifact. It is true that the data must be selected with great care, especially for age groups of small size (e.g. widowers under 25). The observations reported in this paper were selected in the way experiments are designed in physics, that is to say with the objective of minimizing error bars. Data appropriate for mid-age groups may be unsuitable for young age groups and vice versa. The investigation led to the following results. (1) The FB effect is very similar for men and women, except that (at least in western countries) its amplitude is 20% higher for men. (2) There is a marked difference between single/divorced persons on the one hand, for whom the effect is largest around the age of 40, and widowed persons on the other hand, for whom the effect is largest around the age of 25. (3) When different causes of death are distinguished, the effect is largest for suicide and smallest for cancer. For heart disease and cerebrovascular accidents, the fact of being married divides the death rate by 2.2 compared to non-married persons. (4) For young widowers the death rates are up to 10 times higher than for married persons of same age. This extreme form of the FB effect will be referred to as the "young widower effect". Chinese data are used to explore this effect more closely. A possible connection between the FB effect and Martin Raff's "Stay alive" effect for the cells in an organism is discussed in the last section.

  6. Hepcidin detects iron deficiency in Sri Lankan adolescents with a high burden of hemoglobinopathy: A diagnostic test accuracy study

    Science.gov (United States)

    Wray, Katherine; Allen, Angela; Evans, Emma; Fisher, Chris; Premawardhena, Anuja; Perera, Lakshman; Rodrigo, Rexan; Goonathilaka, Gayan; Ramees, Lebbe; Webster, Craig; Armitage, Andrew E; Prentice, Andrew M

    2017-01-01

    Abstract Anemia affects over 800 million women and children globally. Measurement of hepcidin as an index of iron status shows promise, but its diagnostic performance where hemoglobinopathies are prevalent is unclear. We evaluated the performance of hepcidin as a diagnostic test of iron deficiency in adolescents across Sri Lanka. We selected 2273 samples from a nationally representative cross‐sectional study of 7526 secondary schoolchildren across Sri Lanka and analyzed associations between hepcidin and participant characteristics, iron indices, inflammatory markers, and hemoglobinopathy states. We evaluated the diagnostic accuracy of hepcidin as a test for iron deficiency with estimation of the AUCROC, sensitivity/specificity at each hepcidin cutoff, and calculation of the Youden Index to find the optimal threshold. Hepcidin was associated with ferritin, sTfR, and hemoglobin. The AUCROC for hepcidin as a test of iron deficiency was 0.78; hepcidin outperformed Hb and sTfR. The Youden index‐predicted cutoff to detect iron deficiency (3.2 ng/mL) was similar to thresholds previously identified to predict iron utilization and identify deficiency in African populations. Neither age, sex, nor α‐ or β‐thalassemia trait affected diagnostic properties of hepcidin. Hepcidin pre‐screening would prevent most iron‐replete thalassemia carriers from receiving iron whilst still ensuring most iron deficient children were supplemented. Our data indicate that the physiological relationship between hepcidin and iron status transcends specific populations. Measurement of hepcidin in individuals or populations could establish the need for iron interventions. PMID:27883199

  7. High diagnostic accuracy of low-dose gated-SPECT with solid-state ultrafast detectors: preliminary clinical results

    Energy Technology Data Exchange (ETDEWEB)

    Gimelli, Alessia; Genovesi, Dario; Giorgetti, Assuero; Marzullo, Paolo [CNR, Fondazione Toscana Gabriele Monasterio, Pisa (Italy); Bottai, Matteo [University of South Carolina, Division of Biostatistics, Columbia, SC (United States); Karolinska Institutet, Division of Biostatistics, Stockholm (Sweden); Di Martino, Fabio [AOUP, UO Fisica Sanitaria, Pisa (Italy)

    2012-01-15

    Appropriate use of SPECT imaging is regulated by evidence-based guidelines and appropriateness criteria in an effort to limit the burden of radiation administered to patients. We aimed at establishing whether the use of a low dose for stress-rest single-day nuclear myocardial perfusion imaging on an ultrafast (UF) cardiac gamma camera using cadmium-zinc-telluride solid-state detectors could be used routinely with the same accuracy obtained with standard doses and conventional cameras. To this purpose, 137 consecutive patients (mean age 61 {+-} 8 years) with known or suspected coronary artery disease (CAD) were enrolled. They underwent single-day low-dose stress-rest myocardial perfusion imaging using UF SPECT and invasive coronary angiography. Patients underwent the first scan with a 7-min acquisition time 10 min after the end of the stress protocol (dose range 185 to 222 MBq of {sup 99m}Tc-tetrofosmin). The rest scan (dose range 370 to 444 MBq of {sup 99m}Tc-tetrofosmin) was acquired with a 6-min acquisition time. The mean summed stress scores (SSS) and mean summed rest scores (SRS) were obtained semiquantitatively. Coronary angiograms showed significant epicardial CAD in 83% of patients. Mean SSS and SRS were 10 {+-} 5 and 3 {+-} 3, respectively. Overall the area under the ROC curve for the SSS values was 0.904, while the areas under the ROC curves for each vascular territory were 0.982 for the left anterior descending artery, 0.931 for the left circumflex artery and 0.889 for the right coronary artery. This pilot study demonstrated the feasibility of a low-dose single-day stress-rest fasting protocol performed using UF SPECT, with good sensitivity and specificity in detecting CAD at low patient exposure, opening new perspectives in the use of myocardial perfusion in ischaemic patients. (orig.)

  8. Real-time continuous glucose monitoring shows high accuracy within 6 hours after sensor calibration: a prospective study.

    Directory of Open Access Journals (Sweden)

    Xiao-Yan Yue

    Full Text Available Accurate and timely glucose monitoring is essential in intensive care units. Real-time continuous glucose monitoring system (CGMS has been advocated for many years to improve glycemic management in critically ill patients. In order to determine the effect of calibration time on the accuracy of CGMS, real-time subcutaneous CGMS was used in 18 critically ill patients. CGMS sensor was calibrated with blood glucose measurements by blood gas/glucose analyzer every 12 hours. Venous blood was sampled every 2 to 4 hours, and glucose concentration was measured by standard central laboratory device (CLD and by blood gas/glucose analyzer. With CLD measurement as reference, relative absolute difference (mean±SD in CGMS and blood gas/glucose analyzer were 14.4%±12.2% and 6.5%±6.2%, respectively. The percentage of matched points in Clarke error grid zone A was 74.8% in CGMS, and 98.4% in blood gas/glucose analyzer. The relative absolute difference of CGMS obtained within 6 hours after sensor calibration (8.8%±7.2% was significantly less than that between 6 to 12 hours after calibration (20.1%±13.5%, p<0.0001. The percentage of matched points in Clarke error grid zone A was also significantly higher in data sets within 6 hours after calibration (92.4% versus 57.1%, p<0.0001. In conclusion, real-time subcutaneous CGMS is accurate in glucose monitoring in critically ill patients. CGMS sensor should be calibrated less than 6 hours, no matter what time interval recommended by manufacturer.

  9. Determining Geometric Accuracy in Turning

    Institute of Scientific and Technical Information of China (English)

    Kwong; Chi; Kit; A; Geddam

    2002-01-01

    Mechanical components machined to high levels of ac cu racy are vital to achieve various functional requirements in engineering product s. In particular, the geometric accuracy of turned components play an important role in determining the form, fit and function of mechanical assembly requiremen ts. The geometric accuracy requirements of turned components are usually specifi ed in terms of roundness, straightness, cylindricity and concentricity. In pract ice, the accuracy specifications achievable are infl...

  10. High-accuracy 2D digital image correlation measurements using low-cost imaging lenses: implementation of a generalized compensation method

    Science.gov (United States)

    Pan, Bing; Yu, Liping; Wu, Dafang

    2014-02-01

    The ideal pinhole imaging model commonly assumed for an ordinary two-dimensional digital image correlation (2D-DIC) system is neither perfect nor stable because of the existence of small out-of-plane motion of the test sample surface that occurred after loading, small out-of-plane motion of the sensor target due to temperature variation of a camera and unavoidable geometric distortion of an imaging lens. In certain cases, these disadvantages can lead to significant errors in the measured displacements and strains. Although a high-quality bilateral telecentric lens has been strongly recommended to be used in the 2D-DIC system as an essential optical component to achieve high-accuracy measurement, it is not generally applicable due to its fixed field of view, limited depth of focus and high cost. To minimize the errors associated with the imperfectness and instability of a common 2D-DIC system using a low-cost imaging lens, a generalized compensation method using a non-deformable reference sample is proposed in this work. With the proposed method, the displacement of the reference sample rigidly attached behind the test sample is first measured using 2D-DIC, and then it is fitted using a parametric model. The fitted parametric model is then used to correct the displacements of the deformed sample to remove the influences of these unfavorable factors. The validity of the proposed compensation method is first verified using out-of-plane translation, out-of-plane rotation, in-plane translation tests and their combinations. Uniaxial tensile tests of an aluminum specimen were also performed to quantitatively examine the strain accuracy of the proposed compensation method. Experiments show that the proposed compensation method is an easy-to-implement yet effective technique for achieving high-accuracy deformation measurement using an ordinary 2D-DIC system.

  11. Effect of the high-pitch mode in dual-source computed tomography on the accuracy of three-dimensional volumetry of solid pulmonary nodules: A phantom study

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, Sung Ho; Oh, Yu Whan; Ham, Soo Youn [Dept. of Radiology, Korea University Anam Hospital, Seoul (Korea, Republic of); Kang, Eun Young [Dept. of Radiology, Korea University Guro Hospital, Seoul (Korea, Republic of); Lee, Ki Yeol [Dept. of Radiology, Korea University Ansan Hospital, Ansan (Korea, Republic of)

    2015-06-15

    To evaluate the influence of high-pitch mode (HPM) in dual-source computed tomography (DSCT) on the accuracy of three-dimensional (3D) volumetry for solid pulmonary nodules. A lung phantom implanted with 45 solid pulmonary nodules (n = 15 for each of 4-mm, 6-mm, and 8-mm in diameter) was scanned twice, first in conventional pitch mode (CPM) and then in HPM using DSCT. The relative percentage volume errors (RPEs) of 3D volumetry were compared between the HPM and CPM. In addition, the intermode volume variability (IVV) of 3D volumetry was calculated. In the measurement of the 6-mm and 8-mm nodules, there was no significant difference in RPE (p > 0.05, respectively) between the CPM and HPM (IVVs of 1.2 +/- 0.9%, and 1.7 +/- 1.5%, respectively). In the measurement of the 4-mm nodules, the mean RPE in the HPM (35.1 +/- 7.4%) was significantly greater (p < 0.01) than that in the CPM (18.4 +/- 5.3%), with an IVV of 13.1 +/- 6.6%. However, the IVVs were in an acceptable range (< 25%), regardless of nodule size. The accuracy of 3D volumetry with HPM for solid pulmonary nodule is comparable to that with CPM. However, the use of HPM may adversely affect the accuracy of 3D volumetry for smaller (< 5 mm in diameter) nodule.

  12. Inter-comparison of two high-accuracy fast-response spectroscopic sensors of carbon dioxide: a case study

    Directory of Open Access Journals (Sweden)

    B. A. Flowers

    2012-05-01

    Full Text Available Tunable diode laser absorption (TDL and cavity ring-down spectroscopic (CRDS sensors for atmospheric carbon dioxide were co-deployed during summer and fall of 2010 in field and laboratory conditions at Los Alamos National Laboratory. Both sensors were characterized for accuracy and precision for ambient carbon dioxide measurements at ground level and compared using both laboratory and ambient field data. After post-processing that included water vapor correction and calibration to WMO reference standards, overall mean [12C16O2] = 392.05 ± 8.92 ppm and [12C16O2] = 392.22 ± 9.05 ppm were observed between 29 July and 16 August 2010. The mean difference between the CRDS and TDL data for 12CO2 was 0.04 ± 1.80 ppm (±1σ in 60 s for ambient field data, demonstrating the sensors meet the WMO/IAEA compatibility standard. The observations show over the 19-day period the [CO2]CRDS'/[CO2]TDL ratio exhibits a Gaussian distribution centered at x0 = 1.003 ± 3.38 × 10−5 (±1σ, indicating the ratio is dominated by random noise as opposed to a bias in the output of either sensor. The CRDS sensor is capable of measuring [12C16O2] to a precision of 23 ppb in 1 min and decreases to 6.5 ppb in 58 min. At one and 58-min, the TDL exhibits precisions of 29 ppb and 53 ppb. The CRDS is compact, fast, and stable; the TDL is larger and requires frequent calibrations to maintain its precision. The sensors also exhibit consistent hourly averaged diurnal values underscoring the interplay of biological, anthropogenic, and transport processes regulating CO2 at the site.

  13. A Software Module for High-Accuracy Calibration of Rings and Cylinders on CMM using Multi-Orientation Techniques (Multi-Step and Reversal methods)

    DEFF Research Database (Denmark)

    Tosello, Guido; De Chiffre, Leonardo

    . The Centre for Geometrical Metrology (CGM) at the Technical University of Denmark takes care of free form measurements, in collaboration with DIMEG, University of Padova, Italy. The present report describes a software module, ROUNDCAL, to be used for high-accuracy calibration of rings and cylinders....... The purpose of the software is to calculate the form error and the least square circle of rings and cylinders by mean of average of pontwise measuring results becoming from so-called multi-orientation techniques (both reversal and multi-step methods) in order to eliminate systematic errors of CMM ....

  14. A Software Module for High-Accuracy Calibration of Rings and Cylinders on CMM using Multi-Orientation Techniques (Multi-Step and Reversal methods)

    DEFF Research Database (Denmark)

    Tosello, Guido; De Chiffre, Leonardo

    . The Centre for Geometrical Metrology (CGM) at the Technical University of Denmark takes care of free form measurements, in collaboration with DIMEG, University of Padova, Italy. The present report describes a software module, ROUNDCAL, to be used for high-accuracy calibration of rings and cylinders....... The purpose of the software is to calculate the form error and the least square circle of rings and cylinders by mean of average of pontwise measuring results becoming from so-called multi-orientation techniques (both reversal and multi-step methods) in order to eliminate systematic errors of CMM ....

  15. Training Reading Fluency in Dysfluent Readers with High Reading Accuracy: Word Specific Effects but Low Transfer to Untrained Words

    Science.gov (United States)

    Thaler, Verena; Ebner, Eva Maria; Wimmer, Heinz; Landerl, Karin

    2004-01-01

    The outcome of a training study attempting to increase German speaking poor readers' reading fluency is reported. The aim of the training was to help children establish orthographic representations for a limited set of training words as well as for high-frequency onset clusters. A sample of 20 dysfluent readers (8 to 11 years) received a …

  16. High accuracy tracking of 2D/3D curved line-structures by consecutive cross-section matching

    NARCIS (Netherlands)

    Noordmans, H.J.; Smeulders, A.W.M.

    1998-01-01

    Curved 3D line-structures are found in domains such as angiography, cell biology and material science. This paper describes a new algorithm to track the line-structures with high subvoxel precision. Extra parameters determined for each cross-section are: local intensity, size, orientation and match

  17. A high spatial resolution double-pulse Thomson scattering diagnostic; description, assessment of accuracy and examples of applications

    NARCIS (Netherlands)

    Beurskens, M. N. A.; Barth, C. J.; Cardozo, N. J. L.; van der Meiden, H. J.

    1999-01-01

    A high spatial resolution (3 mm full width half maximum, i.e. 2% of the minor radius) double-pulse multiposition Thomson scattering system was in operation at the Rijnhuizen tokamak project RTP from March 1996 until September 1998. It upgrades the previously installed single-pulse Thomson scattering

  18. Dose prediction accuracy of anisotropic analytical algorithm and pencil beam convolution algorithm beyond high density heterogeneity interface

    Directory of Open Access Journals (Sweden)

    Suresh B Rana

    2013-01-01

    Full Text Available Purpose: It is well known that photon beam radiation therapy requires dose calculation algorithms. The objective of this study was to measure and assess the ability of pencil beam convolution (PBC and anisotropic analytical algorithm (AAA to predict doses beyond high density heterogeneity. Materials and Methods: An inhomogeneous phantom of five layers was created in Eclipse planning system (version 8.6.15. Each layer of phantom was assigned in terms of water (first or top, air (second, water (third, bone (fourth, and water (fifth or bottom medium. Depth doses in water (bottom medium were calculated for 100 monitor units (MUs with 6 Megavoltage (MV photon beam for different field sizes using AAA and PBC with heterogeneity correction. Combinations of solid water, Poly Vinyl Chloride (PVC, and Styrofoam were then manufactured to mimic phantoms and doses for 100 MUs were acquired with cylindrical ionization chamber at selected depths beyond high density heterogeneity interface. The measured and calculated depth doses were then compared. Results: AAA′s values had better agreement with measurements at all measured depths. Dose overestimation by AAA (up to 5.3% and by PBC (up to 6.7% was found to be higher in proximity to the high-density heterogeneity interface, and the dose discrepancies were more pronounced for larger field sizes. The errors in dose estimation by AAA and PBC may be due to improper beam modeling of primary beam attenuation or lateral scatter contributions or combination of both in heterogeneous media that include low and high density materials. Conclusions: AAA is more accurate than PBC for dose calculations in treating deep-seated tumor beyond high-density heterogeneity interface.

  19. Rapid screening of drugs of abuse in human urine by high-performance liquid chromatography coupled with high resolution and high mass accuracy hybrid linear ion trap-Orbitrap mass spectrometry.

    Science.gov (United States)

    Li, Xiaowen; Shen, Baohua; Jiang, Zheng; Huang, Yi; Zhuo, Xianyi

    2013-08-09

    A novel analytical toxicology method has been developed for the analysis of drugs of abuse in human urine by using a high resolution and high mass accuracy hybrid linear ion trap-Orbitrap mass spectrometer (LTQ-Orbitrap-MS). This method allows for the detection of different drugs of abuse, including amphetamines, cocaine, opiate alkaloids, cannabinoids, hallucinogens and their metabolites. After solid-phase extraction with Oasis HLB cartridges, spiked urine samples were analysed by HPLC/LTQ-Orbitrap-MS using an electrospray interface in positive ionisation mode, with resolving power of 30,000 full width at half maximum (FWHM). Gradient elution off of a Hypersil Gold PFP column (50mm×2.1mm) allowed to resolve 65 target compounds and 3 internal standards in a total chromatographic run time of 20min. Validation of this method consisted of confirmation of identity, selectivity, linearity, limit of detection (LOD), lowest limits of quantification (LLOQ), accuracy, precision, extraction recovery and matrix effect. The regression coefficients (r(2)) for the calibration curves (LLOQ - 100ng/mL) in the study were ≥0.99. The LODs for 65 validated compounds were better than 5ng/ml except for 4 compounds. The relative standard deviation (RSD), which was used to estimate repeatability at three concentrations, was always less than 15%. The recovery of extraction and matrix effects were above 50 and 70%, respectively. Mass accuracy was always better than 2ppm, corresponding to a maximum mass error of 0.8 millimass units (mmu). The accurate masses of characteristic fragments were obtained by collisional experiments for a more reliable identification of the analytes. Automated data analysis and reporting were performed using ToxID software with an exact mass database. This procedure was then successfully applied to analyse drugs of abuse in a real urine sample from subject who was assumed to be drug addict.

  20. The Drift Diffusion Model can account for the accuracy and reaction time of value-based choices under high and low time pressure

    Directory of Open Access Journals (Sweden)

    Milica Milosavljevic

    2010-10-01

    Full Text Available An important open problem is how values are compared to make simple choices. A natural hypothesis is that the brain carries out the computations associated with the value comparisons in a manner consistent with the Drift Diffusion Model (DDM, since this model has been able to account for a large amount of data in other domains. We investigated the ability of four different versions of the DDM to explain the data in a real binary food choice task under conditions of high and low time pressure. We found that a seven-parameter version of the DDM can account for the choice and reaction time data with high-accuracy, in both the high and low time pressure conditions. The changes associated with the introduction of time pressure could be traced to changes in two key model parameters: the barrier height and the noise in the slope of the drift process.

  1. A simple high accuracy phase locked loop method%一种内同步高精度锁相环技术研究

    Institute of Scientific and Technical Information of China (English)

    耿攀; 吴卫民; 陈建明; 叶银忠; 刘以建

    2011-01-01

    本文提出一种适用于数字控制的内同步高精度锁相环方法.本方法实现简单,在系统正常工作情况下可以高精度跟踪电网同步信号.在失去电网同步信号后依然可以使系统按照原来的频率和相位继续稳定运行,更适用于需要在并网、离网自由切换工作的系统.本文首先详细分析了此处带内同步程序锁相环的工作原理,然后推导了采用这种锁相方法的具体精度,最后通过1kW样机实验验证了提出方法的正确性.%This paper proposes a simple high accuracy inner-synchronization phase locked loop method used for digital control. This method is very easy to be realized. When the system works under normal condition, it could track the grid synchronized signal in high accuracy. When the system losses the grid synchronized signal, it could keep stable operation under the former frequency and phase position, and it is more suitable for the systems which need to switch between grid-tied and stand-alone mode. In this paper, the working principle of the phase locked loop with inner-synchronized program is analyzed at first. The accuracy using this phase locked loop method is derived. Finally, experimental results on a l kW prototype prove the validity of the proposed method.

  2. Building Next-Generation Technologies for Low-Cost Gene Synthesis and High-Accuracy Genome Engineering

    OpenAIRE

    2014-01-01

    The technologies that enable writing and editing of DNA form the foundation of modern molecular biology and biotechnology. However, a number of methodological barriers have limited the widespread adoption of both high-throughput de novo gene synthesis and large-scale genome alteration. Increasingly, work in the fields of synthetic biology, protein design, and gene therapy has been hindered by shortcomings in current DNA writing and editing technologies. The goal of this dissertation has be...

  3. Experimental Validation of a High Accuracy Test of the Equivalence Principle with the Small Satellite "GALILEO GALILEI"

    Science.gov (United States)

    Nobili, Anna M.; Comandi, Gian Luca; Doravari, Suresh; Maccarrone, Francesco; Bramanti, Donato; Polacco, Erseo

    The small satellite "Galileo Galilei" (GG) has been designed to test the equivalence principle (EP) to 10-17 with a total mass at launch of 250 kg. The key instrument is a differential accelerometer made up of weakly coupled coaxial, concentric test cylinders rapidly spinning around the symmetry axis and sensitive in the plane perpendicular to it, lying at a small inclination from the orbit plane. The whole spacecraft spins around the same symmetry axis so as to be passively stabilized. The test masses are large (10 kg each, to reduce thermal noise), their coupling is very weak (for high sensitivity to differential effects), and rotation is fast (for high frequency modulation of the signal). A 1 g version of the accelerometer ("Galileo Galilei on the Ground" — GGG) has been built to the full scale — except for coupling, which cannot be as weak as in the absence of weight, and a motor to maintain rotation (not needed in space due to angular momentum conservation). GGG has proved: (i) high Q; (ii) auto-centering and long term stability; (iii) a sensitivity to EP testing which is close to the target sensitivity of the GG experiment provided that the physical properties of the experiment in space are going to be fully exploited.

  4. Wind velocity measurement accuracy with highly stable 12 mJ/pulse high repetition rate CO2 laser master oscillator power amplifier

    Science.gov (United States)

    Bilbro, James W.; Johnson, Steven C.; Rothermel, Jeffry

    1987-01-01

    A coherent CO2 lidar operating in a master oscillator power amplifier configuration (MOPA) is described for both ground-based and airborne operation. Representative data taken from measurements against stationary targets in both the ground-based and airborne configurations are shown for the evaluation of the frequency stability of the system. Examples of data are also given which show the results of anomalous system operation. Overall results demonstrate that velocity measurements can be performed consistently to an accuracy of + or - 0.5 m/s and in some cases + or - 0.1 m/s.

  5. 确定生态系统模型中高精度参数的研究%Research on Determining the High Accuracy Parameters in Ecosystem Model

    Institute of Scientific and Technical Information of China (English)

    蒋社想

    2013-01-01

    针对Lotka-Volterra生态系统模型中的高精度参数如何确定问题,本文通过对长期积累的观测数据进行分析,提出先对误差数据进行卡尔曼滤波器将噪声滤除,然后利用最小二乘曲线进行拟合,以确定模型中的参数在最小二乘曲线意义下的最优解,最后利用M atlab和M aple计算机软件进行了模拟仿真,结果表明该方法对高精度参数确定问题有一定的有效性。%Determining the high accuracy parameters of the Lotka -Volterra ecosystem models is a wor-thy research .Based on the long -term accumulation of analyzing observation data ,an approaching of Kalman Filter was proposed for noise filtering to error data in this paper ,then a least -squares curve fitting was used to determine the optimal solution of model parameters ,finally a simulation was tested by using the Matlab and Maple software .The result shows that the presented approach of determining high accuracy parameters has a certain effect .

  6. Using ProtMAX to create high-mass-accuracy precursor alignments from label-free quantitative mass spectrometry data generated in shotgun proteomics experiments.

    Science.gov (United States)

    Egelhofer, Volker; Hoehenwarter, Wolfgang; Lyon, David; Weckwerth, Wolfram; Wienkoop, Stefanie

    2013-03-01

    Recently, new software tools have been developed for improved protein quantification using mass spectrometry (MS) data. However, there are still limitations especially in high-sample-throughput quantification methods, and most of these relate to extensive computational calculations. The mass accuracy precursor alignment (MAPA) strategy has been shown to be a robust method for relative protein quantification. Its major advantages are high resolution, sensitivity and sample throughput. Its accuracy is data dependent and thus best suited for precursor mass-to-charge precision of ∼1 p.p.m. This protocol describes how to use a software tool (ProtMAX) that allows for the automated alignment of precursors from up to several hundred MS runs within minutes without computational restrictions. It comprises features for 'ion intensity count' and 'target search' of a distinct set of peptides. This procedure also includes the recommended MS settings for complex quantitative MAPA analysis using ProtMAX (http://www.univie.ac.at/mosys/software.html).

  7. 高精度超声风速测量系统设计与实现%Design and Implementation of High Accuracy Ultrasonic Anemometer

    Institute of Scientific and Technical Information of China (English)

    丁向辉; 李平; 孟晓辉

    2011-01-01

    时差法是超声风速风向测量系统的基本方法.文中首先对影响时差法测量精度的因素进行分析,针对这些影响因素,在超声换能器设计、阵型设计、电路系统设计和信号处理算法等方面提出了提高系统精度的设计方案,并制成样机.实验测试表明,文中所实现的系统已经基本达到国际尖端产品的测量精度,且具有体积小、可靠性高等优点,具有很高的实际应用价值.%In ultrasonic anemometer systems,time difference measurement method is used in wide range. The factors that affect the time difference measurement accuracy were analyzed. According to the analysis, the ultrasonic transducer design , system mechanical structure,system circuit design and signal processing; methods were discussed. A high accuracy ultrasonic anemometer 8ystem solution was designed. The prototype system was implemented. Experiments show that the proposed system has reached the same performance as the top products on shelf. Besides , the system has small size , high resolution and reliability , which is valuable in practice.

  8. Classification of textures in satellite image with Gabor filters and a multi layer perceptron with back propagation algorithm obtaining high accuracy

    Directory of Open Access Journals (Sweden)

    Adriano Beluco, Paulo M. Engel, Alexandre Beluco

    2015-01-01

    Full Text Available The classification of images, in many cases, is applied to identify an alphanumeric string, a facial expression or any other characteristic. In the case of satellite images is necessary to classify all the pixels of the image. This article describes a supervised classification method for remote sensing images that integrates the importance of attributes in selecting features with the efficiency of artificial neural networks in the classification process, resulting in high accuracy for real images. The method consists of a texture segmentation based on Gabor filtering followed by an image classification itself with an application of a multi layer artificial neural network with a back propagation algorithm. The method was first applied to a synthetic image, like training, and then applied to a satellite image. Some results of experiments are presented in detail and discussed. The application of the method to the synthetic image resulted in the identification of 89.05% of the pixels of the image, while applying to the satellite image resulted in the identification of 85.15% of the pixels. The result for the satellite image can be considered a result of high accuracy.

  9. Fast converging with high accuracy estimates of satellite attitude and orbit based on magnetometer augmented with gyro, star sensor and GPS via extended Kalman filter

    Directory of Open Access Journals (Sweden)

    Tamer Mekky Ahmed Habib

    2011-12-01

    Full Text Available The primary goal of this work is to extend the work done in, Tamer (2009, to provide high accuracy satellite attitude and orbit estimates needed for imaging purposes and also before execution of spacecraft orbital maneuvers for the next Egyptian scientific satellite. The problem of coarse satellite attitude and orbit estimation based on magnetometer measurements has been treated in the literature. The current research expands the field of application from coarse and slow converging estimates to accurate and fast converging attitude and orbit estimates within 0.1°, and 10 m for attitude angles and spacecraft location respectively (1-σ. The magnetometer is used for both spacecraft attitude and orbit estimation, aided with gyro to provide angular velocity measurements, star sensor to provide attitude quaternion, and GPS receiver to provide spacecraft location. The spacecraft under consideration is subject to solar radiation pressure forces and moments, aerodynamics forces and moments, earth’s oblateness till the fourth order (i.e. J4, gravity gradient moments, and residual magnetic dipole moments. The estimation algorithm developed is powerful enough to converge quickly (actually within 10 s despite very large initial estimation errors with sufficiently high accuracy estimates.

  10. High-accuracy imputation for HLA class I and II genes based on high-resolution SNP data of population-specific references.

    Science.gov (United States)

    Khor, S-S; Yang, W; Kawashima, M; Kamitsuji, S; Zheng, X; Nishida, N; Sawai, H; Toyoda, H; Miyagawa, T; Honda, M; Kamatani, N; Tokunaga, K

    2015-12-01

    Statistical imputation of classical human leukocyte antigen (HLA) alleles is becoming an indispensable tool for fine-mappings of disease association signals from case-control genome-wide association studies. However, most currently available HLA imputation tools are based on European reference populations and are not suitable for direct application to non-European populations. Among the HLA imputation tools, The HIBAG R package is a flexible HLA imputation tool that is equipped with a wide range of population-based classifiers; moreover, HIBAG R enables individual researchers to build custom classifiers. Here, two data sets, each comprising data from healthy Japanese individuals of difference sample sizes, were used to build custom classifiers. HLA imputation accuracy in five HLA classes (HLA-A, HLA-B, HLA-DRB1, HLA-DQB1 and HLA-DPB1) increased from the 82.5-98.8% obtained with the original HIBAG references to 95.2-99.5% with our custom classifiers. A call threshold (CT) of 0.4 is recommended for our Japanese classifiers; in contrast, HIBAG references recommend a CT of 0.5. Finally, our classifiers could be used to identify the risk haplotypes for Japanese narcolepsy with cataplexy, HLA-DRB1*15:01 and HLA-DQB1*06:02, with 100% and 99.7% accuracy, respectively; therefore, these classifiers can be used to supplement the current lack of HLA genotyping data in widely available genome-wide association study data sets.

  11. Geoid undulation accuracy

    Science.gov (United States)

    Rapp, Richard H.

    1993-01-01

    The determination of the geoid and equipotential surface of the Earth's gravity field, has long been of interest to geodesists and oceanographers. The geoid provides a surface to which the actual ocean surface can be compared with the differences implying information on the circulation patterns of the oceans. For use in oceanographic applications the geoid is ideally needed to a high accuracy and to a high resolution. There are applications that require geoid undulation information to an accuracy of +/- 10 cm with a resolution of 50 km. We are far from this goal today but substantial improvement in geoid determination has been made. In 1979 the cumulative geoid undulation error to spherical harmonic degree 20 was +/- 1.4 m for the GEM10 potential coefficient model. Today the corresponding value has been reduced to +/- 25 cm for GEM-T3 or +/- 11 cm for the OSU91A model. Similar improvements are noted by harmonic degree (wave-length) and in resolution. Potential coefficient models now exist to degree 360 based on a combination of data types. This paper discusses the accuracy changes that have taken place in the past 12 years in the determination of geoid undulations.

  12. Liquid theory with high accuracy and broad applicability: Coupling parameter series expansion and non hard sphere perturbation strategy

    Science.gov (United States)

    Zhou, Shiqi

    2011-12-01

    Thermodynamic and structural properties of liquids are of fundamental interest in physics, chemistry, and biology, and perturbation approach has been fundamental to liquid theoretical approaches since the dawn of modern statistical mechanics and remains so to this day. Although thermodynamic perturbation theory (TPT) is widely used in the chemical physics community, one of the most popular versions of the TPT, i.e. Zwanzig (Zwanzig, R. W. J. Chem. Phys. 1954, 22, 1420-1426) 1st-order high temperature series expansion (HTSE) TPT and its 2nd-order counterpart under a macroscopic compressibility approximation of Barker-Henderson (Barker, J. A.; Henderson, D. J. Chem. Phys. 1967, 47, 2856-2861), have some serious shortcomings: (i) the nth-order term of the HTSE is involved with reference fluid distribution functions of order up to 2n, and the higher-order terms hence progressively become more complicated and numerically inaccessible; (ii) the performance of the HTSE rapidly deteriorates and the calculated results become even qualitatively incorrect as the temperature of interest decreases. This account deals with the developments that we have made over the last five years or so to advance a coupling parameter series expansion (CPSE) and a non hard sphere (HS) perturbation strategy that has scored some of its greatest successes in overcoming the above-mentioned difficulties. In this account (i) we expatiate on implementation details of our schemes: how input information indispensable to high-order truncation of the CPSE in both the HS and non HS perturbation schemes is calculated by an Ornstein-Zernike integral equation theory; how high-order thermodynamic quantities, such as critical parameters and excess constant volume heat capacity, are extracted from the resulting excess Helmholtz free energy with irregular and inevitable numerical errors; how to select reference potential in the non HS perturbation scheme. (ii) We give a quantitative analysis on why convergence

  13. Liquid theory with high accuracy and broad applicability: Coupling parameter series expansion and non hard sphere perturbation strategy

    Directory of Open Access Journals (Sweden)

    Shiqi Zhou

    2011-12-01

    Full Text Available Thermodynamic and structural properties of liquids are of fundamental interest in physics, chemistry, and biology, and perturbation approach has been fundamental to liquid theoretical approaches since the dawn of modern statistical mechanics and remains so to this day. Although thermodynamic perturbation theory (TPT is widely used in the chemical physics community, one of the most popular versions of the TPT, i.e. Zwanzig (Zwanzig, R. W. J. Chem. Phys. 1954, 22, 1420-1426 1st-order high temperature series expansion (HTSE TPT and its 2nd-order counterpart under a macroscopic compressibility approximation of Barker-Henderson (Barker, J. A.; Henderson, D. J. Chem. Phys. 1967, 47, 2856-2861, have some serious shortcomings: (i the nth-order term of the HTSE is involved with reference fluid distribution functions of order up to 2n, and the higher-order terms hence progressively become more complicated and numerically inaccessible; (ii the performance of the HTSE rapidly deteriorates and the calculated results become even qualitatively incorrect as the temperature of interest decreases. This account deals with the developments that we have made over the last five years or so to advance a coupling parameter series expansion (CPSE and a non hard sphere (HS perturbation strategy that has scored some of its greatest successes in overcoming the above-mentioned difficulties. In this account (i we expatiate on implementation details of our schemes: how input information indispensable to high-order truncation of the CPSE in both the HS and non HS perturbation schemes is calculated by an Ornstein-Zernike integral equation theory; how high-order thermodynamic quantities, such as critical parameters and excess constant volume heat capacity, are extracted from the resulting excess Helmholtz free energy with irregular and inevitable numerical errors; how to select reference potential in the non HS perturbation scheme. (ii We give a quantitative analysis on why

  14. High-accuracy and robust face recognition system based on optical parallel correlator using a temporal image sequence

    Science.gov (United States)

    Watanabe, Eriko; Ishikawa, Mami; Ohta, Maiko; Kodate, Kashiko

    2005-09-01

    Face recognition is used in a wide range of security systems, such as monitoring credit card use, searching for individuals with street cameras via Internet and maintaining immigration control. There are still many technical subjects under study. For instance, the number of images that can be stored is limited under the current system, and the rate of recognition must be improved to account for photo shots taken at different angles under various conditions. We implemented a fully automatic Fast Face Recognition Optical Correlator (FARCO) system by using a 1000 frame/s optical parallel correlator designed and assembled by us. Operational speed for the 1: N (i.e. matching a pair of images among N, where N refers to the number of images in the database) identification experiment (4000 face images) amounts to less than 1.5 seconds, including the pre/post processing. From trial 1: N identification experiments using FARCO, we acquired low error rates of 2.6% False Reject Rate and 1.3% False Accept Rate. By making the most of the high-speed data-processing capability of this system, much more robustness can be achieved for various recognition conditions when large-category data are registered for a single person. We propose a face recognition algorithm for the FARCO while employing a temporal image sequence of moving images. Applying this algorithm to a natural posture, a two times higher recognition rate scored compared with our conventional system. The system has high potential for future use in a variety of purposes such as search for criminal suspects by use of street and airport video cameras, registration of babies at hospitals or handling of an immeasurable number of images in a database.

  15. Assessment of geometry in 2D immune systems using high accuracy laser-based bioprinting techniques (Conference Presentation)

    Science.gov (United States)

    Lauzurica, Sara; Márquez, Andrés.; Molpeceres, Carlos; Notario, Laura; Gómez-Fontela, Miguel; Lauzurica, Pilar

    2017-02-01

    The immune system is a very complex system that comprises a network of genetic and signaling pathways subtending a network of interacting cells. The location of the cells in a network, along with the gene products they interact with, rules the behavior of the immune system. Therefore, there is a great interest in understanding properly the role of a cell in such networks to increase our knowledge of the immune system response. In order to acquire a better understanding of these processes, cell printing with high spatial resolution emerges as one of the promising approaches to organize cells in two and three-dimensional patterns to enable the study the geometry influence in these interactions. In particular, laser assisted bio-printing techniques using sub-nanosecond laser sources have better characteristics for application in this field, mainly due to its higher spatial resolution, cell viability percentage and process automation. This work presents laser assisted bio-printing of antigen-presenting cells (APCs) in two-dimensional geometries, placing cellular components on a matrix previously generated on demand, permitting to test the molecular interactions between APCs and lymphocytes; as well as the generation of two-dimensional structures designed ad hoc in order to study the mechanisms of mobilization of immune system cells. The use of laser assisted bio-printing, along with APCs and lymphocytes emulate the structure of different niches of the immune system so that we can analyse functional requirement of these interaction.

  16. High accuracy thermal conductivity measurement of aqueous cryoprotective agents and semi-rigid biological tissues using a microfabricated thermal sensor.

    Science.gov (United States)

    Liang, Xin M; Sekar, Praveen K; Zhao, Gang; Zhou, Xiaoming; Shu, Zhiquan; Huang, Zhongping; Ding, Weiping; Zhang, Qingchuan; Gao, Dayong

    2015-05-20

    An improved thermal-needle approach for accurate and fast measurement of thermal conductivity of aqueous and soft biomaterials was developed using microfabricated thermal conductivity sensors. This microscopic measuring device was comprehensively characterized at temperatures from 0 °C to 40 °C. Despite the previous belief, system calibration constant was observed to be highly temperature-dependent. Dynamic thermal conductivity response during cooling (40 °C to -40 °C) was observed using the miniaturized single tip sensor for various concentrations of CPAs, i.e., glycerol, ethylene glycol and dimethyl sulfoxide. Chicken breast, chicken skin, porcine limb, and bovine liver were assayed to investigate the effect of anatomical heterogeneity on thermal conductivity using the arrayed multi-tip sensor at 20 °C. Experimental results revealed distinctive differences in localized thermal conductivity, which suggests the use of approximated or constant property values is expected to bring about results with largely inflated uncertainties when investigating bio-heat transfer mechanisms and/or performing sophisticated thermal modeling with complex biological tissues. Overall, the presented micro thermal sensor with automated data analysis algorithm is a promising approach for direct thermal conductivity measurement of aqueous solutions and soft biomaterials and is of great value to cryopreservation of tissues, hyperthermia or cryogenic, and other thermal-based clinical diagnostics and treatments.

  17. Training reading fluency in dysfluent readers with high reading accuracy: word specific effects but low transfer to untrained words.

    Science.gov (United States)

    Thaler, Verena; Ebner, Eva Maria; Wimmer, Heinz; Landerl, Karin

    2004-06-01

    The outcome of a training study attempting to increase German speaking poor readers' reading fluency is reported. The aim of the training was to help children establish orthographic representations for a limited set of training words as well as for high-frequency onset clusters. A sample of 20 dysfluent readers (8-11 years) received a computerized training of repeated reading of a limited set of 32 training words over a period of up to 25 days. Each day training words were presented up to six times with a special emphasis on the onset segment. Post-tests were carried out one and five weeks after the last training day. A considerable decrease in reading times could be achieved for the trained words that remained stable for both post-tests, however, even for the limited set of training words a remarkable amount of repetitions did not lead to age adequate word recognition speed. Generalization to untrained words starting with a trained onset cluster (transfer words) was statistically reliable but small.

  18. Hydroxyl radical-PLIF measurements and accuracy investigation in high pressure gaseous hydrogen/gaseous oxygen combustion

    Science.gov (United States)

    Vaidyanathan, Aravind

    In-flow species concentration measurements in reacting flows at high pressures are needed both to improve the current understanding of the physical processes taking place and to validate predictive tools that are under development, for application to the design and optimization of a range of power plants from diesel to rocket engines. To date, non intrusive measurements have been based on calibrations determined from assumptions that were not sufficiently quantified to provide a clear understanding of the range of uncertainty associated with these measurements. The purpose of this work is to quantify the uncertainties associated with OH measurement in a oxygen-hydrogen system produced by a shear, coaxial injector typical of those used in rocket engines. Planar OH distributions are obtained providing instantaneous and averaged distribution that are required for both LES and RANS codes currently under development. This study has evaluated the uncertainties associated with OH measurement at 10, 27, 37 and 53 bar respectively. The total rms error for OH-PLIF measurements from eighteen different parameters was quantified and found as 21.9, 22.8, 22.5, and 22.9% at 10, 27, 37 and 53 bar respectively. These results are used by collaborators at Georgia Institute of Technology (LES), Pennsylvania State University (LES), University of Michigan (RANS) and NASA Marshall (RANS).

  19. Accuracy of high-field intraoperative MRI in the detectability of residual tumor in glioma grade IV resections

    Energy Technology Data Exchange (ETDEWEB)

    Hesselmann, Volker; Mager, Ann-Kathrin [Asklepios-Klinik Nord, Hamburg (Germany). Radiology/Neurologie; Goetz, Claudia; Kremer, Paul [Asklepios-Klinik Nord, Hamburg (Germany). Dept. of Neurosurgery; Detsch, Oliver [Asklepios-Klinik Nord, Hamburg (Germany). Dept. of Anaesthesiology and Intensive Care Medicine; Theisgen, Hannah-Katharina [Universitaetsklinikum Schleswig-Holstein, Kiel (Germany). Dept. of Neurosurgery; Friese, Michael; Gottschalk, Joachim [Asklepios-Klinik Nord, Hamburg (Germany). Dept. of Pathology and Neuropathology; Schwindt, Wolfram [Univ. Hospital Muenster (Germany). Dept. of Clinical Radiology

    2017-06-15

    To assess the sensitivity/specificity of tumor detection by T1 contrast enhancement in intraoperative MRI (ioMRI) in comparison to histopathological assessment as the gold standard in patients receiving surgical resection of grade IV glioblastoma. 68 patients with a primary or a recurrent glioblastoma scheduled for surgery including fluorescence guidance and neuronavigation were included (mean age: 59 years, 26 female, 42 male patients). The ioMRI after the first resection included transverse FLAIR, DWI, T2-FFE and T1 - 3 d FFE ± GD-DPTA. The second resection was performed whenever residual contrast-enhancing tissue was detected on ioMRI. Resected tissue samples were histopathologically evaluated (gold standard). Additionally, we evaluated the early postoperative MRI scan acquired within 48 h post-OP for remaining enhancing tissue and compared them with the ioMRI scan. In 43 patients ioMRI indicated residual tumorous tissue, which could be confirmed in the histological specimens of the second resection. In 16 (4 with recurrent, 12 with primary glioblastoma) cases, ioMRI revealed truly negative results without residual tumor and follow-up MRI confirmed complete resection. In 7 cases (3 with recurrent, 4 with primary glioblastoma) ioMRI revealed a suspicious result without tumorous tissue in the histopathological workup. In 2 (1 for each group) patients, residual tumorous tissue was detected in spite of negative ioMRI. IoMRI had a sensitivity of 95 % (94 % recurrent and 96 % for primary glioblastoma) and a specificity of 69.5 % (57 % and 75 %, respectively). The positive predictive value was 86 % (84 % for recurrent and 87 % for primary glioblastoma), and the negative predictive value was 88 % (80 % and 92 %, respectively). ioMRI is effective for detecting remaining tumorous tissue after glioma resection. However, scars and leakage of contrast agent can be misleading and limit specificity. Intraoperative MRI (ioMRI) presents with a high sensitivity for residual

  20. GG high accuracy test of the equivalence principle: state of the art, laboratory prototype and new insights

    Science.gov (United States)

    Nobili, Anna M.; Pegna, Raffaello; Comandi, Gian Luca; Bramanti, Donato; Anselmi, Alberto; Catastini, Giuseppe

    The GG ("Galileo Galilei") satellite experiment aims to test the Equivalence Principle (EP) to 10-17 , an extremely ambitious goal (due to improve current best results by 4 orders of magnitude) that should tell us in a clear cut way whether we are in the presence of a new long-range physical interaction (violation) or not (confirmation). Either way, it would be a major result. An end-to-end space experiment simulator was constructed at TAS-I based on GOCE simulator and ASI (Agenzia Spaziale Italiana) funding. The resulting error budget is consistent with the mission goal, which can be realized in 4 years from the start of Phase B. In the lab, a full scale prototype has provided a 25 days continuous run with a sensitivity -in the field of the Sun, hence at diurnal frequency- of a few nanometers in the relative displacement of the proof masses, to be compared with the picometer level required in space for GG to achieve its goal. A passive suspended prototype is under completion in order to reduce ground platform noise by means of an appropriate cardanic suspension which has now been proved to be able to reduce diurnal terrain noise by a factor 104 . The crucial issue of thermal noise has been recently revisited and a major new insight has come thanks to M. Shao (JPL): in GG, by up-converting the frequency of an EP violation signal in the field of the Earth from its (low) orbital frequency of 1.7 · 10-4 Hz to the (high) rotation/modulation frequency of 1Hz -the highest ever in EP experiments- proof mass thermal noise is reduced by orders of magnitude, as the ratio of these frequencies squared. Instead, cooling the experiment to superfluid He temperature would only reduce thermal noise by a factor 10. This is a feature unique to GG. It now appears that, if equipped with an intrinsic differential transducer such as a SIM like laser gauge, GG may indeed aim to an EP test to 10-18 . The end-to-end GG simulator built at TAS-I in 2009 during GG Phase A-2 study is the

  1. Gravity Compensation Methods for High-Accuracy INS%高精度惯性导航系统重力补偿方法

    Institute of Scientific and Technical Information of China (English)

    陆志东; 王晶

    2016-01-01

    重力扰动是高精度惯性导航系统的一项重要误差源,重力补偿是降低惯性导航系统误差的一项关键技术。通过基于对确定性模型、数据及外部辅助3种重力补偿方法的分析和研究,总结得出了各补偿方法的研究方向以及适用范围,对进一步提高我国未来更高精度惯性导航系统的导航精度具有指导意义,并提供了方法上的参考。%Gravity disturbance is an important error source of high-accuracy inertial navigation system(INS). Gravity compensation is a critical technology to reduce error of INS. After analysing and researching deterministic model,data and external assist gravity compensation methods,research area and range of application were summarized. It can provide guidance and reference to improve INS’s navigation accuracy.

  2. The absence of longitudinal data limits the accuracy of high-throughput clinical phenotyping for identifying type 2 diabetes mellitus subjects.

    Science.gov (United States)

    Wei, Wei-Qi; Leibson, Cynthia L; Ransom, Jeanine E; Kho, Abel N; Chute, Christopher G

    2013-04-01

    To evaluate the impact of insufficient longitudinal data on the accuracy of a high-throughput clinical phenotyping (HTCP) algorithm for identifying (1) patients with type 2 diabetes mellitus (T2DM) and (2) patients with no diabetes. Retrospective study conducted at Mayo Clinic in Rochester, Minnesota. Eligible subjects were Olmsted County residents with ≥1 Mayo Clinic encounter in each of three time periods: (1) 2007, (2) from 1997 through 2006, and (3) before 1997 (N = 54,283). Diabetes relevant electronic medical record (EMR) data about diagnoses, laboratories, and medications were used. We employed the HTCP algorithm to categorize individuals as T2DM cases and non-diabetes controls. Considering the full 11 years (1997-2007) as the gold standard, we compared gold-standard categorizations with those using data for 10 subsequent intervals, ranging from 1998-2007 (10-year data) to 2007 (1-year data). Positive predictive values (PPVs) and false-negative rates (FNRs) were calculated. McNemar tests were used to determine whether categorizations using shorter time periods differed from the gold standard. Statistical significance was defined as P FNRs, respectively, were 70% and 25% for case identification and 59% and 67% for control identification. All time frames differed significantly from the gold standard, except for the 10-year period. The accuracy of the algorithm reduced remarkably as data were limited to shorter observation periods. This impact should be considered carefully when designing/executing HTCP algorithms. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  3. Simultaneous determination of triazine herbicides in rice by high-performance liquid chromatography coupled with high resolution and high mass accuracy hybrid linear ion trap-orbitrap mass spectrometry.

    Science.gov (United States)

    Mou, Ren-Xiang; Chen, Ming-Xue; Cao, Zhao-Yun; Zhu, Zhi-Wei

    2011-11-07

    A method was developed for the simultaneous determination of 10 triazine herbicides (cyanazine, simazine, simetryn, metribuzin, atrazine, ametryn, terbuthylazine, prometryn, terbutryn, and dimethametryn) in rice samples by high resolution and high mass accuracy hybrid linear ion trap-Orbitrap mass spectrometer. After extraction with acetonitrile and evaporation, the herbicides were redissolved in n-hexane and purified on a Florisil solid-phase extraction column. All compounds were separated within 12 min, producing more than 11 data points for each herbicide and high mass accuracy quantified ions which the mass errors of absolute value were less than 1.9 ppm in pure solution and 2.1 ppm in the matrix-matched standards solution. The method was validated in terms of the limits of detection and the limits of quantification. The linearity was satisfactory, with a correlation coefficient of >0.9975. Precision and recovery studies were evaluated at three concentration levels for Japonica, Indica, and Glutinous rice matrix. The mean recoveries obtained for all analytes in spiked Xiushui 03, Liangyoupeijiu, and Taihunuo rice samples were 83.3-99.0%, 82.0-99.7%, and 84.2-99.4%, respectively, with relative standard deviation in range 1.7-10.6%, 1.2-10.7%, and 1.9-11.6% for spiked rice samples, respectively. The intra-day precision (n=5) for the 10 herbicides in rice samples spiked at an intermediate level was between 2.8% and 7.9%, and the inter-day precision over 10 days (n=10) was between 5.5% and 15.9%.

  4. High accuracy NMR chemical shift corrected for bulk magnetization as a tool for structural elucidation of dilutable microemulsions. Part 1 - Proof of concept.

    Science.gov (United States)

    Hoffman, Roy E; Darmon, Eliezer; Aserin, Abraham; Garti, Nissim

    2016-02-01

    In microemulsions, changes in droplet size and shape and possible transformations occur under various conditions. They are difficult to characterize by most analytical tools because of their nano-sized structure and dynamic nature. Several methods are usually combined to obtain reliable information, guiding the scientist in understanding their physical behavior. We felt that there is a need for a technique that complements those in use today in order to provide more information on the microemulsion behavior, mainly as a function of dilution with water. The improvement of NMR chemical shift measurements independent of bulk magnetization effects makes it possible to study the very weak intermolecular chemical shift effects. In the present study, we used NMR high resolution magic angle spinning to measure the chemical shift very accurately, free of bulk magnetization effects. The chemical shift of microemulsion components is measured as a function of the water content in order to validate the method in an interesting and promising, U-type dilutable microemulsion, which had been previously studied by a variety of techniques. Phase transition points of the microemulsion (O/W, bicontinuous, W/O) and changes in droplet shape were successfully detected using high-accuracy chemical shift measurements. We analyzed the results and found them to be compatible with the previous studies, paving the way for high-accuracy chemical shifts to be used for the study of other microemulsion systems. We detected two transition points along the water dilution line of the concentrate (reverse micelles) corresponding to the transition from swollen W/O nano-droplets to bicontinuous to the O/W droplets along with the changes in the droplets' sizes and shapes. The method seems to be in excellent agreement with other previously studied techniques and shows the advantage of this easy and valid technique.

  5. Development of X-Y Servo Pneumatic-Piezoelectric Hybrid Actuators for Position Control with High Response, Large Stroke and Nanometer Accuracy

    Directory of Open Access Journals (Sweden)

    Mao-Hsiung Chiang

    2010-03-01

    Full Text Available This study aims to develop a X-Y dual-axial intelligent servo pneumatic-piezoelectric hybrid actuator for position control with high response, large stroke (250 mm, 200 mm and nanometer accuracy (20 nm. In each axis, the rodless pneumatic actuator serves to position in coarse stroke and the piezoelectric actuator compensates in fine stroke. Thus, the overall control systems of the single axis become a dual-input single-output (DISO system. Although the rodless pneumatic actuator has relatively larger friction force, it has the advantage of mechanism for multi-axial development. Thus, the X-Y dual-axial positioning system is developed based on the servo pneumatic-piezoelectric hybrid actuator. In addition, the decoupling self-organizing fuzzy sliding mode control is developed as the intelligent control strategies. Finally, the proposed novel intelligent X-Y dual-axial servo pneumatic-piezoelectric hybrid actuators are implemented and verified experimentally.

  6. Development of X-Y Servo Pneumatic-Piezoelectric Hybrid Actuators for Position Control with High Response, Large Stroke and Nanometer Accuracy

    Science.gov (United States)

    Chiang, Mao-Hsiung

    2010-01-01

    This study aims to develop a X-Y dual-axial intelligent servo pneumatic-piezoelectric hybrid actuator for position control with high response, large stroke (250 mm, 200 mm) and nanometer accuracy (20 nm). In each axis, the rodless pneumatic actuator serves to position in coarse stroke and the piezoelectric actuator compensates in fine stroke. Thus, the overall control systems of the single axis become a dual-input single-output (DISO) system. Although the rodless pneumatic actuator has relatively larger friction force, it has the advantage of mechanism for multi-axial development. Thus, the X-Y dual-axial positioning system is developed based on the servo pneumatic-piezoelectric hybrid actuator. In addition, the decoupling self-organizing fuzzy sliding mode control is developed as the intelligent control strategies. Finally, the proposed novel intelligent X-Y dual-axial servo pneumatic-piezoelectric hybrid actuators are implemented and verified experimentally. PMID:22319266

  7. High Accuracy Reference Network (HARN), We use the HARN that the State of WIsconsin Department of Transportation installed in 2005., Published in 2005, 1:600 (1in=50ft) scale, Lafayette County Land Records.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This High Accuracy Reference Network (HARN) dataset, published at 1:600 (1in=50ft) scale, was produced all or in part from Field Survey/GPS information as of 2005....

  8. James Webb Space Telescope Integrated Science Instrument Module Calibration and Verification of High-Accuracy Instrumentation to Measure Heat Flow in Cryogenic Testing

    Science.gov (United States)

    Comber, Brian; Glazer, Stuart

    2012-01-01

    The James Webb Space Telescope (JWST) is an upcoming flagship observatory mission scheduled to be launched in 2018. Three of the four science instruments are passively cooled to their operational temperature range of 36K to 40K, and the fourth instrument is actively cooled to its operational temperature of approximately 6K. The requirement for multiple thermal zoned results in the instruments being thermally connected to five external radiators via individual high purity aluminum heat straps. Thermal-vacuum and thermal balance testing of the flight instruments at the Integrated Science Instrument Module (ISIM) element level will take place within a newly constructed shroud cooled by gaseous helium inside Goddard Space Flight Center's (GSFC) Space environment Simulator (SES). The flight external radiators are not available during ISIM-level thermal vacuum/thermal testing, so they will be replaced in test with stable and adjustable thermal boundaries with identical physical interfaces to the flight radiators. Those boundaries are provided by specially designed test hardware which also measures the heat flow within each of the five heat straps to an accuracy of less than 2 mW, which is less than 5% of the minimum predicted heat flow values. Measurement of the heat loads to this accuracy is essential to ISIM thermal model correlation, since thermal models are more accurately correlated when temperature data is supplemented by accurate knowledge of heat flows. It also provides direct verification by test of several high-level thermal requirements. Devices that measure heat flow in this manner have historically been referred to a "Q-meters". Perhaps the most important feature of the design of the JWST Q-meters is that it does not depend on the absolute accuracy of its temperature sensors, but rather on knowledge of precise heater power required to maintain a constant temperature difference between sensors on two stages, for which a table is empirically developed during a

  9. High Accuracy Fast Floating-point Algorithm on Radar Terminal System%雷达终端高精度快速浮点算法研究

    Institute of Scientific and Technical Information of China (English)

    韩文俊; 张晓明; 杨东华

    2012-01-01

    In radar terminal system, floating-point operation when implemented in FPGA is time-consuming and with high resource u-tilization. After comparing current floating-point processing methods, CORDIC algorithm with high processing performance is selected. The theory of CORDIC algorithm is introduced in depth and the influence of bit wide and the iteration numbers to the accuracy is discussed by simulating. Finally, the implementation of arctan function in FPGA as an example is presented in detail. The results show that the speed is up to 210 MHz, the resource utilization is lower and the accuracy is higher which is also easy adjusted.%针对雷达终端处理过程中,浮点运算在现场可编程门阵列(FPGA)中实现较为耗时、资源占用较高的问题,首先在分析对比当前主要浮点处理方法的基础上,选择CORDIC算法进行浮点处理,并对算法原理进行了详细的介绍,通过仿真,分析了位宽及迭代次数对精度的影响.然后,以arctan函数为例详细介绍了其在FPGA中实现的方法,结果显示arctan流水运算速度可达200 MHz,资源占用率较低、实时性强、精度较高且易于调整.

  10. Noncontrast perfusion single-photon emission CT/CT scanning: a new test for the expedited, high-accuracy diagnosis of acute pulmonary embolism.

    Science.gov (United States)

    Lu, Yang; Lorenzoni, Alice; Fox, Josef J; Rademaker, Jürgen; Vander Els, Nicholas; Grewal, Ravinder K; Strauss, H William; Schöder, Heiko

    2014-05-01

    Standard ventilation and perfusion (V˙/Q˙) scintigraphy uses planar images for the diagnosis of pulmonary embolism (PE). To evaluate whether tomographic imaging improves the diagnostic accuracy of the procedure, we compared noncontrast perfusion single-photon emission CT (Q˙-SPECT)/CT scans with planar V˙/Q˙scans in patients at high risk for PE. Between 2006 and 2010, most patients referred for diagnosis of PE underwent both Q˙-SPECT/CT scan and planar V˙/Q˙scintigraphy. All scans were reviewed retrospectively by four observers; planar scans were read with modified Prospective Investigation of Pulmonary Embolism Diagnosis (PIOPED) II and Prospective Investigative Study of Pulmonary Embolism Diagnosis (PISA-PED) criteria. On Q˙-SPECT/CT scan, any wedge-shaped peripheral perfusion defect occupying > 50% of a segment without corresponding pulmonary parenchymal or pleural disease was considered to show PE. The final diagnosis was established with a composite reference standard that included ECG, ultrasound of lower-extremity veins, D-dimer levels, CT pulmonary angiography (when available), and clinical follow-up for at least 3 months. One hundred six patients with cancer and mean Wells score of 4.4 had sufficient follow-up; 22 patients were given a final diagnosis of PE, and 84 patients were given a final diagnosis of no PE. According to PIOPED II, 13 studies were graded as intermediate probability. Sensitivity and specificity for PE were 50% and 98%, respectively, based on PIOPED II criteria; 86% and 93%, respectively, based on PISA-PED criteria; and 91% and 94%, respectively, based on Q˙-SPECT/CT scan. Seventy-six patients had additional relevant findings on the CT image of the Q˙-SPECT/CT scan. Noncontrast Q˙-SPECT/CT imaging has a higher accuracy than planar V˙/Q˙imaging based on PIOPED II criteria in patients with cancer and a high risk for PE.

  11. INTRODUCING NOVEL GENERATION OF HIGH ACCURACY CAMERA OPTICAL-TESTING AND CALIBRATION TEST-STANDS FEASIBLE FOR SERIES PRODUCTION OF CAMERAS

    Directory of Open Access Journals (Sweden)

    M. Nekouei Shahraki

    2015-12-01

    Full Text Available The recent advances in the field of computer-vision have opened the doors of many opportunities for taking advantage of these techniques and technologies in many fields and applications. Having a high demand for these systems in today and future vehicles implies a high production volume of video cameras. The above criterions imply that it is critical to design test systems which deliver fast and accurate calibration and optical-testing capabilities. In this paper we introduce new generation of test-stands delivering high calibration quality in single-shot calibration of fisheye surround-view cameras. This incorporates important geometric features from bundle-block calibration, delivers very high (sub-pixel calibration accuracy, makes possible a very fast calibration procedure (few seconds, and realizes autonomous calibration via machines. We have used the geometrical shape of a Spherical Helix (Type: 3D Spherical Spiral with special geometrical characteristics, having a uniform radius which corresponds to the uniform motion. This geometrical feature was mechanically realized using three dimensional truncated icosahedrons which practically allow the implementation of a spherical helix on multiple surfaces. Furthermore the test-stand enables us to perform many other important optical tests such as stray-light testing, enabling us to evaluate the certain qualities of the camera optical module.

  12. Diagnostic accuracy of sensitive or high-sensitive troponin on presentation for myocardial infarction: a meta-analysis and systematic review

    Directory of Open Access Journals (Sweden)

    Sethi A

    2014-07-01

    Full Text Available Ankur Sethi,1 Anurag Bajaj,2 Gurveen Malhotra,1 Rohit R Arora,1 Sandeep Khosla1 1Department of Medicine, Division of Cardiology, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA; 2Department of Medicine, Wright Center of Graduate Medical Education, Scranton, PA, USA Background: Recently, high-sensitive troponin (hsTrop assays consistent with professional societies' recommendations became available. We aimed to summarize the evidence on the diagnostic accuracy of hsTrop on presentation. Methods: We searched electronic databases for studies evaluating the diagnostic accuracy of hsTrop in suspected acute coronary syndrome (ACS patients. Random effect meta-analyses and meta-regression were performed. Primary and secondary analyses were restricted to studies using conventional Trop and hsTrop in the reference standard, respectively. Results: Fifteen studies with a total of 8,628 patients met the inclusion criteria for the primary analysis. hsTrop T (Hoffman-La Roche Ltd and hsTrop I (Siemens had sensitivities of 0.89 (95% confidence interval [CI]: 0.86–0.91 and 0.90 (95% CI: 0.87–0.92 and specificities of 0.79 (95% CI: 0.77–0.80 and 0.89 (95% CI: 0.87–0.90, respectively. There was no statistically significant difference in the area under the curve between hsTrop (95% CI: 0.920 and conventional Trop (95% CI: 0.929 at the 99th percentile (P=0.62. hsTrop at the level of detection had a sensitivity of 0.97 (95% CI: 0.96–0.98 and a specificity of 0.41 (95% CI: 0.40–0.42. The studies using a cut-off at coefficient of variance <10% as opposed to the 99th percentile for the conventional assay used for diagnosis reported higher diagnostic accuracy (relative diagnostic odds ratio =2.13, P=0.02. Five studies were included in the secondary analysis; hsTrop T (Hoffman-La Roche Ltd had a sensitivity of 0.91 (95% CI: 0.89–0.93 and a specificity of 0.67 (95% CI: 0.63–0.70. There was significant heterogeneity among the

  13. Integration of PET-CT and cone-beam CT for image-guided radiotherapy with high image quality and registration accuracy

    Science.gov (United States)

    Wu, T.-H.; Liang, C.-H.; Wu, J.-K.; Lien, C.-Y.; Yang, B.-H.; Huang, Y.-H.; Lee, J. J. S.

    2009-07-01

    Hybrid positron emission tomography-computed tomography (PET-CT) system enhances better differentiation of tissue uptake of 18F-fluorodeoxyglucose (18F-FDG) and provides much more diagnostic value in the non-small-cell lung cancer and nasopharyngeal carcinoma (NPC). In PET-CT, high quality CT images not only offer diagnostic value on anatomic delineation of the tissues but also shorten the acquisition time for attenuation correction (AC) compared with PET-alone imaging. The linear accelerators equipped with the X-ray cone-beam computed tomography (CBCT) imaging system for image-guided radiotherapy (IGRT) provides excellent verification on position setup error. The purposes of our study were to optimize the CT acquisition protocols of PET-CT and to integrate the PET-CT and CBCT for IGRT. The CT imaging parameters were modified in PET-CT for increasing the image quality in order to enhance the diagnostic value on tumour delineation. Reproducibility and registration accuracy via bone co-registration algorithm between the PET-CT and CBCT were evaluated by using a head phantom to simulate a head and neck treatment condition. Dose measurement in computed tomography dose index (CTDI) was also estimated. Optimization of the CT acquisition protocols of PET-CT was feasible in this study. Co-registration accuracy between CBCT and PET-CT on axial and helical modes was in the range of 1.06 to 2.08 and 0.99 to 2.05 mm, respectively. In our result, it revealed that the accuracy of the co-registration with CBCT on helical mode was more accurate than that on axial mode. Radiation doses in CTDI were 4.76 to 18.5 mGy and 4.83 to 18.79 mGy on axial and helical modes, respectively. Registration between PET-CT and CBCT is a state-of-the-art registration technology which could provide much information on diagnosis and accurate tumour contouring on radiotherapy while implementing radiotherapy procedures. This novelty technology of PET-CT and cone-beam CT integration for IGRT may have a

  14. Integration of PET-CT and cone-beam CT for image-guided radiotherapy with high image quality and registration accuracy

    Energy Technology Data Exchange (ETDEWEB)

    Wu, T-H [Department of Medical Imaging and Radiological Sciences, Chung Shan Medical University, No. 110, Sec.1, Jianguo N.Rd, Taichung City 40201, Taiwan (China); Liang, C-H [Agfa Healthcare Systems Taiwan Co., Ltd., 6F, 237 Sung Chiang Road, Taipei, 104 Taiwan (China); Wu, J-K [Division of Radiation Oncology, Department of Oncology, and Cancer Research Center, National Taiwan University Hospital, No.7 Chung San South Road, Taipei, 104 Taiwan (China); Lien, C-Y [Institute of Biomedical Engineering, National Yang Ming University, No. 155, Sec.2, Linong Street, Taipei, 112 Taiwan (China); Yang, B-H; Lee, J J S [Department of Biomedical Imaging and Radiological Sciences, National Yang Ming University, No. 155, Sec.2, Linong Street, Taipei, 112 Taiwan (China); Huang, Y-H [Department of Medical Imaing and Radiological Sciences, I-Shou University, No. 8, Yida Rd., Yanchao Township, Kaohsiung County 82445, Taiwan (China)], E-mail: jslee@ym.edu.tw

    2009-07-15

    Hybrid positron emission tomography-computed tomography (PET-CT) system enhances better differentiation of tissue uptake of {sup 18}F-fluorodeoxyglucose ({sup 18}F-FDG) and provides much more diagnostic value in the non-small-cell lung cancer and nasopharyngeal carcinoma (NPC). In PET-CT, high quality CT images not only offer diagnostic value on anatomic delineation of the tissues but also shorten the acquisition time for attenuation correction (AC) compared with PET-alone imaging. The linear accelerators equipped with the X-ray cone-beam computed tomography (CBCT) imaging system for image-guided radiotherapy (IGRT) provides excellent verification on position setup error. The purposes of our study were to optimize the CT acquisition protocols of PET-CT and to integrate the PET-CT and CBCT for IGRT. The CT imaging parameters were modified in PET-CT for increasing the image quality in order to enhance the diagnostic value on tumour delineation. Reproducibility and registration accuracy via bone co-registration algorithm between the PET-CT and CBCT were evaluated by using a head phantom to simulate a head and neck treatment condition. Dose measurement in computed tomography dose index (CTDI) was also estimated. Optimization of the CT acquisition protocols of PET-CT was feasible in this study. Co-registration accuracy between CBCT and PET-CT on axial and helical modes was in the range of 1.06 to 2.08 and 0.99 to 2.05 mm, respectively. In our result, it revealed that the accuracy of the co-registration with CBCT on helical mode was more accurate than that on axial mode. Radiation doses in CTDI were 4.76 to 18.5 mGy and 4.83 to 18.79 mGy on axial and helical modes, respectively. Registration between PET-CT and CBCT is a state-of-the-art registration technology which could provide much information on diagnosis and accurate tumour contouring on radiotherapy while implementing radiotherapy procedures. This novelty technology of PET-CT and cone-beam CT integration for IGRT

  15. 四阶杆振动方程的两类高精度辛格式%TWO CLASSES OF SYMPLECTIC SCHEMES WITH HIGH ORDER ACCURACY FOR FOUR-ORDER ROD VIBRATION EQUATION

    Institute of Scientific and Technical Information of China (English)

    曾文平

    2004-01-01

    In this paper, we present two classes of symplectic schemes with high order accuracy for solving four-order rod vibration equation utt+uxxxx=0 via the third type generating function method. First, the equation of four order rod vibration is written into the canonical Hamilton system; second, overcoming successfully the essential difficult on the calculus of high order variations derivative, we get the semi-discretization with arbitrary order of accuracy in time direction for the PDEs by the third type generating function method. Furthermore the discretization of the related modified equation of original equation is obtained. Finally, arbitrary order accuracy symplectic schemes are obtained. Numerical results are also presented to show the effectiveness of the scheme, high order accuracy and properties of excellent long-time numerical behavior.

  16. [Improved patient repositioning accuracy by integrating an additional jaw fixation into a high precision face mask system in stereotactic radiotherapy of the head].

    Science.gov (United States)

    Lopatta, Eric; Liesenfeld, Susie-Maria; Bank, Priska; Wurm, Reinhard; Günther, Robert; Wiezorek, Tilo; Wendt, Thomas G

    2003-08-01

    For high precision radiotherapy of the neurocranium a precise, reproducible positioning technique is the basic prerequisite. The aim of this study was to assess the influence of a modification of the commercially available stereotactical BrainLab-head mask system on accuracy in patient positioning during fractionated radiotherapy. 29 patients were treated with stereotactic radiotherapy of the head. Immobilization was provided by a two layer thermoplastic mask system (BrainLab). 18 of these patients received an additional custom made fixation either of the upper jaw (OKF) or of the mandibula (UKF). The positioning accuracy was assessed by measurements of the shifting of anatomical landmarks in relation to the rigid mask system on biplanar simulator films using a digital imaging system. Before each measurement a fine adjustment of the simulator to an optical ring system was performed. The reference radiographs were done just before CT-planning. During a 2-7 weeks lasting course of radiotherapy displacement measurements in relation to the reference images for all three dimensions (z, y and x) were done once a week. In 29 patients 844 measurements were analyzed. An additional jaw fixation improves the reproducibility of patient positioning significantly in all three spatial dimensions. The standard deviation in lateral direction (x) was 0.6 mm with jaw fixation vs. 0.7 mm without jaw fixation (p jaw fixation can be acquired. The variability of positioning can be reduced especially in the z-direction. A further reduction of the safety margin around the target volume--especially in benign tumors--is possible by improved fixation technique.

  17. Accuracy of dual-source CT coronary angiography: first experience in a high pre-test probability population without heart rate control

    Energy Technology Data Exchange (ETDEWEB)

    Scheffel, Hans; Alkadhi, Hatem; Desbiolles, Lotus; Frauenfelder, Thomas; Schertler, Thomas; Husmann, Lars; Marincek, Borut; Leschka, Sebastian [University Hospital Zurich, Institute of Diagnostic Radiology, Zurich (Switzerland); Plass, Andre; Vachenauer, Robert; Grunenfelder, Juerg; Genoni, Michele [Clinic for Cardiovascular Surgery, Zurich (Switzerland); Gaemperli, Oliver; Schepis, Tiziano [University Hospital Zurich, Cardiovascular Center, Zurich (Switzerland); Kaufmann, Philipp A. [University Hospital Zurich, Cardiovascular Center, Zurich (Switzerland); University of Zurich, Center for Integrative Human Physiology, Zurich (Switzerland)

    2006-12-15

    The aim of this study was to assess the diagnostic accuracy of dual-source computed tomography (DSCT) for evaluation of coronary artery disease (CAD) in a population with extensive coronary calcifications without heart rate control. Thirty patients (24 male, 6 female, mean age 63.1{+-}11.3 years) with a high pre-test probability of CAD underwent DSCT coronary angiography and invasive coronary angiography (ICA) within 14{+-}9 days. No beta-blockers were administered prior to the scan. Two readers independently assessed image quality of all coronary segments with a diameter {>=}1.5 mm using a four-point score (1: excellent to 4: not assessable) and qualitatively assessed significant stenoses as narrowing of the luminal diameter >50%. Causes of false-positive (FP) and false-negative (FN) ratings were assigned to calcifications or motion artifacts. ICA was considered the standard of reference. Mean body mass index was 28.3{+-}3.9 kg/m{sup 2} (range 22.4-36.3 kg/m{sup 2}), mean heart rate during CT was 70.3{+-}14.2 bpm (range 47-102 bpm), and mean Agatston score was 821{+-}904 (range 0-3,110). Image quality was diagnostic (scores 1-3) in 98.6% (414/420) of segments (mean image quality score 1.68{+-}0.75); six segments in three patients were considered not assessable (1.4%). DSCT correctly identified 54 of 56 significant coronary stenoses. Severe calcifications accounted for false ratings in nine segments (eight FP/one FN) and motion artifacts in two segments (one FP/one FN). Overall sensitivity, specificity, positive and negative predictive value for evaluating CAD were 96.4, 97.5, 85.7, and 99.4%, respectively. First experience indicates that DSCT coronary angiography provides high diagnostic accuracy for assessment of CAD in a high pre-test probability population with extensive coronary calcifications and without heart rate control. (orig.)

  18. SU-D-BRE-04: Evaluating the Dose Accuracy of a 2D Ion Chamber Array in High Dose Rate Pencil Beam Scanning Proton Beam

    Energy Technology Data Exchange (ETDEWEB)

    Perles, L; Mascia, A; Piskulich, F; Lepage, R; Zhang, Y; Giebeler, A; Dong, L [Scripps Proton Therapy Center, San Diego, CA (United States)

    2014-06-01

    Purpose: To evaluate the absolute dose accuracy of the PTW Octavius 729 XDR 2D ion chamber array at a high dose rate pencil beam scanning proton therapy facility. Methods: A set of 18 plans were created in our treatment planning system, each of which comprising a unique combination of field sizes (FS), length of spread out of Bragg peaks (SOBP) and depths. The parameters used were: FS of 5×5cm{sup 2}, 10×10cm{sup 2} and 15×15cm{sup 2}; flat SOBP of 5cm and 10cm; and isocenter depths of 10cm, 15cm and 20cm, which coincides with the center of the SOBP. The 2D array detector was positioned at the machine isocenter and the appropriate amount of solid water was used to match the planned depths of 10, 15 and 20 cm water equivalent depth. Subsequently, we measured the absolute dose at isocenter using a CC04 ion chamber in a 1D water tank. Both 2D array and CC04 were previously cross calibrated. We also collected the MU rates used by our proton machine from the log files. Results: The relative differences between the CC04 and the 2D array can be summarized into two groups, one with 5 cm SOBP and another with 10 cm SOBP. Plotting these datasets against FS shows that the 2D array response for high dose rate fields (FS of 5×5cm{sup 2} and 5cm SOBP) can be up to 2% lower. Similarly, plotting them against isocenter depths reveals the detector's response can be up to 2% lower for higher energy beams (about 200MeV nominal). The MU rate found in the machine log files for 5cm SOBP's were as high as twice the MU rate for the 10cm SOBP. Conclusion: The 2D array dose response showed a dose rate effect in scanning pencil beam delivery, which needs to be corrected to achieve a better dose accuracy.

  19. Meditation Experience Predicts Introspective Accuracy

    Science.gov (United States)

    Fox, Kieran C. R.; Zakarauskas, Pierre; Dixon, Matt; Ellamil, Melissa; Thompson, Evan; Christoff, Kalina

    2012-01-01

    The accuracy of subjective reports, especially those involving introspection of one's own internal processes, remains unclear, and research has demonstrated large individual differences in introspective accuracy. It has been hypothesized that introspective accuracy may be heightened in persons who engage in meditation practices, due to the highly introspective nature of such practices. We undertook a preliminary exploration of this hypothesis, examining introspective accuracy in a cross-section of meditation practitioners (1–15,000 hrs experience). Introspective accuracy was assessed by comparing subjective reports of tactile sensitivity for each of 20 body regions during a ‘body-scanning’ meditation with averaged, objective measures of tactile sensitivity (mean size of body representation area in primary somatosensory cortex; two-point discrimination threshold) as reported in prior research. Expert meditators showed significantly better introspective accuracy than novices; overall meditation experience also significantly predicted individual introspective accuracy. These results suggest that long-term meditators provide more accurate introspective reports than novices. PMID:23049790

  20. 高阶抛物型方程的一族高精度恒稳差分格式%A FAMILY OF ABSOLUTELY STABLE DIFFERENCE SCHEMES OF HIGH ACCURACY FOR SOLVING HIGH ORDER PARABALIC EQUATION

    Institute of Scientific and Technical Information of China (English)

    曾文平

    2003-01-01

    A family of three-layer implicit difference Schemes of high accuracy with two parameters for solving high order parabolic equationδu/δt=(-1)m+1δ2mu/δx2m(where m is positive integers) are constructed. In the special case α=1/2, β=0, We obtain a two-layer difference scheme. These schemes are proved to be absolutely stable for arbiratily chosen non-negative parameters, And the order of the truncation error is O((△t)2+(△x)6). They are shown by numerical examples to be effective, and practice consistant with theoretical analysis.

  1. High accuracy measurement of the $^{235}$U(n,f) reaction cross-section in the 10-30 keV neutron energy range

    CERN Multimedia

    The analysis of the neutron flux of n_TOF (in EAR1) revealed an anomaly in the 10-30 keV neutron energy range. While the flux extracted on the basis of the $^{6}$Li(n,t)$^{4}$He and $^{10}$B(n,$\\alpha$)$^{7}$Li reactions mostly agreed with each other and with the results of FLUKA simulations of the neutron beam, the one based on the $^{235}$U(n,f) reaction was found to be systematically lower, independently of the detection system used. A possible explanation is that the $^{235}$U(n,f) crosssection in that energy region, where in principle should be known with an uncertainty of 1%, may be systematically overestimated. Such a finding, which has a negligible influence on thermal reactors, would be important for future fast critical or subcritical reactors. Furthermore, its interest is more general, since the $^{235}$U(n,f) reaction is often used at that energy to determine the neutron flux, or as reference in measurements of fission cross section of other actinides. We propose to perform a high-accuracy, high-r...

  2. Spectral responsivity calibration of the reference radiation thermometer at KRISS by using a super-continuum laser-based high-accuracy monochromatic source

    Science.gov (United States)

    Yoo, Yong Shim; Kim, Gun Jung; Park, Seongchong; Lee, Dong-Hoon; Kim, Bong-Hak

    2016-12-01

    We report on the calibration of the relative spectral responsivity of the reference radiation thermometer, model LP4, which is used for the experimental realisation of the international temperature scale of 1990 above 960 °C at the Korea Research Institute of Standards and Science. The relative spectral responsivity of LP4 is measured by using a monochromatic source consisting of a super-continuum laser and a double-grating monochromator. By monitoring the wavelength of the output beam directly with a calibrated wavelength-meter, we achieved a high-accuracy measurement of spectral responsivity with a maximum wavelength error of less than 3 pm, a narrow spectral bandwidth of less than 0.4 nm, and a high dynamic range over 8 decades. We evaluated the contributions of various uncertainty components of the spectral responsivity measurement to the uncertainty of the temperature scale based on a practical estimation approach, which numerically calculates the maximal effects of the variations of each component. As a result, we evaluate the uncertainty contribution from the spectral responsivity measurement to the temperature scale to be less than 64 mK (k  =  1) in a range from 660 °C to 2749 °C for the LP4 with a filter at 650 nm.

  3. ExoMol molecular line lists XIX: high-accuracy computed hot line lists for H218O and H217O

    Science.gov (United States)

    Polyansky, Oleg L.; Kyuberis, Aleksandra A.; Lodi, Lorenzo; Tennyson, Jonathan; Yurchenko, Sergei N.; Ovsyannikov, Roman I.; Zobov, Nikolai F.

    2017-04-01

    Hot line lists for two isotopologues of water, H218O and H217O, are presented. The calculations employ newly constructed potential energy surfaces (PES), which take advantage of a novel method for using the large set of experimental energy levels for H216O to give high-quality predictions for H218O and H217O. This procedure greatly extends the energy range for which a PES can be accurately determined, allowing an accurate prediction of higher lying energy levels than are currently known from direct laboratory measurements. This PES is combined with a high-accuracy, ab initio dipole moment surface of water in the computation of all energy levels, transition frequencies and associated Einstein A coefficients for states with rotational excitation up to J = 50 and energies up to 30 000 cm-1. The resulting HotWat78 line lists complement the well-used BT2 H216O line list. Full line lists are made available online as Supporting Information and at www.exomol.com.

  4. Seismic refraction analysis with high accuracy based on traveltime modeling; Basu keisan wo base to shita kussekiho jishin tansa kaiseki no koseidoka

    Energy Technology Data Exchange (ETDEWEB)

    Saito, H.; Hayashi, K. [OYO Corp., Tokyo (Japan)

    1996-05-01

    For the purpose of enhancing the efficiency of analytical processes so that those not equipped with high skill may perform a certain level of analysis and that analysis precision may be improved, some analytical techniques based on path calculation were examined. As the result, a flow of work has become feasible, wherein an early model is constructed by use of a tomography-assisted analysis to be accomplished automatedly and the result is then converted into a layer system with the velocity and thickness to be automatically corrected for the determination of the ultimate velocity layer section. Following this flow of work, almost all the parts of the work may be accomplished automatically once the travel time curve is completed. Furthermore, the calculated travel time obtained by this method can be easily compared with the observed travel time creating an opportunity to show the high reliability of this method, for this to be accepted as a standard for evaluating the accuracy of exploration. It has also been found that this method may be applied to more complicated structures which fail to satisfy the conditions for a structure to be treated by other methods such as `Hagiwara`s method.` 3 refs., 5 figs.

  5. SU-E-T-433: Calibration Accuracy in Mailed High-Resolution 3D Dosimetry Service for SRS/SBRT QA

    Energy Technology Data Exchange (ETDEWEB)

    Maryanski, M [MGS Research Inc, Madison, CT (United States); Keane, J; Zimberg, S [Advanced Radiation Centers of New York, Islandia, NY (United States)

    2014-06-01

    Purpose: SRS/SBRT combines hypofractionation with excellent dose distributions. However, extremely steep gradients across the target along with dose escalation, if not administered accurately, may lead to serious complications, recurrences, or even fatalities. Existing commercial QA products either lack adequate spatial resolution or the 3D aspect. By contrast, the new CrystalBall™ mailed high-resolution 3D dosimetry service removes the above limitations while reducing the overall workload on medical physics staff. The exposed dosimeters, which change optical density in proportion to local dose, are sent back to the manufacturer (MGS Research Inc., Madison, CT) for sub-millimeter-resolution laser-CT scanning and QA data analysis. QA report is returned electronically within 24 hours. The purpose of this study was to evaluate the dose calibration accuracy in this system. Methods: Two spherical CrystalBall™ polymer gel dosimeters from the same batch, 166 mm diameter, with embedded 3D image registration markers, were mounted in a special phantom designed for reproducible positioning. For full end to end testing, the optical guidance array was mounted onto the phantom and a CT was taken. Two separate Rapid Arc SRS plans were designed. Varian Medical Systems optical guidance system was used to position the phantom and the SRS treatment plans were delivered to the two spheres on Varian's Trilogy Accelerator. Exposed dosimeters were mailed back to the manufacturer for laser CT scanning and analysis. Results: For each plan, 3D gamma passing rate was 100% for 2%/2mm distance-to-agreement criteria above 50% isodose level. The two calibration curves, generated using volumetric dose and optical density data, showed excellent mutual agreement (max difference 2.2%, median difference 0.75%). Conclusion: The clinical utility of new CrystalBall™ mailed QA service for SRS/SBRT and high accuracy of dose calibration have been validated. The workflow associated with the use

  6. High Accuracy of Common HIV-Related Oral Disease Diagnoses by Non-Oral Health Specialists in the AIDS Clinical Trial Group.

    Directory of Open Access Journals (Sweden)

    Caroline H Shiboski

    Full Text Available Many studies include oral HIV-related endpoints that may be diagnosed by non-oral-health specialists (non-OHS like nurses or physicians. Our objective was to assess the accuracy of clinical diagnoses of HIV-related oral lesions made by non-OHS compared to diagnoses made by OHS.A5254, a cross-sectional study conducted by the Oral HIV/AIDS Research Alliance within the AIDS Clinical Trial Group, enrolled HIV-1-infected adults participants from six clinical trial units (CTU in the US (San Francisco, New York, Chapel Hill, Cleveland, Atlanta and Haiti. CTU examiners (non-OHS received standardized training on how to perform an oral examination and make clinical diagnoses of specific oral disease endpoints. Diagnoses by calibrated non-OHS were compared to those made by calibrated OHS, and sensitivity and specificity computed.Among 324 participants, the majority were black (73%, men (66%, and the median CD4+ cell count 138 cells/mm(3. The overall frequency of oral mucosal disease diagnosed by OHS was 43% in US sites, and 90% in Haiti. Oral candidiasis (OC was detected in 153 (47% by OHS, with erythematous candidiasis (EC the most common type (39% followed by pseudomembranous candidiasis (PC; 26%. The highest prevalence of OC (79% was among participants in Haiti, and among those with CD4+ cell count ≤ 200 cells/mm(3 and HIV-1 RNA > 1000 copies/mL (71%. The sensitivity and specificity of OC diagnoses by non-OHS were 90% and 92% (for EC: 81% and 94%; PC: 82% and 95%. Sensitivity and specificity were also high for KS (87% and 94%, respectively, but sensitivity was < 60% for HL and oral warts in all sites combined. The Candida culture confirmation of OC clinical diagnoses (as defined by ≥ 1 colony forming unit per mL of oral/throat rinse was ≥ 93% for both PC and EC.Trained non-OHS showed high accuracy of clinical diagnoses of OC in comparison with OHS, suggesting their usefulness in studies in resource-poor settings, but detection of less common

  7. Fusion of lens-free microscopy and mobile-phone microscopy images for high-color-accuracy and high-resolution pathology imaging

    Science.gov (United States)

    Zhang, Yibo; Wu, Yichen; Zhang, Yun; Ozcan, Aydogan

    2017-03-01

    Digital pathology and telepathology require imaging tools with high-throughput, high-resolution and accurate color reproduction. Lens-free on-chip microscopy based on digital in-line holography is a promising technique towards these needs, as it offers a wide field of view (FOV >20 mm2) and high resolution with a compact, low-cost and portable setup. Color imaging has been previously demonstrated by combining reconstructed images at three discrete wavelengths in the red, green and blue parts of the visible spectrum, i.e., the RGB combination method. However, this RGB combination method is subject to color distortions. To improve the color performance of lens-free microscopy for pathology imaging, here we present a wavelet-based color fusion imaging framework, termed "digital color fusion microscopy" (DCFM), which digitally fuses together a grayscale lens-free microscope image taken at a single wavelength and a low-resolution and low-magnification color-calibrated image taken by a lens-based microscope, which can simply be a mobile phone based cost-effective microscope. We show that the imaging results of an H&E stained breast cancer tissue slide with the DCFM technique come very close to a color-calibrated microscope using a 40x objective lens with 0.75 NA. Quantitative comparison showed 2-fold reduction in the mean color distance using the DCFM method compared to the RGB combination method, while also preserving the high-resolution features of the lens-free microscope. Due to the cost-effective and field-portable nature of both lens-free and mobile-phone microscopy techniques, their combination through the DCFM framework could be useful for digital pathology and telepathology applications, in low-resource and point-of-care settings.

  8. A Novel AOA Clustering-based Localization Algorithm with High Accuracy%高精度AOA分簇定位算法

    Institute of Scientific and Technical Information of China (English)

    黄琦; 黄海; 谢冬青

    2014-01-01

    如今的网络安全主要联系于无线传感网络,定位算法的优劣决定了无线传感网络的能力,也就决定了网络安全的能力。分簇定位算法具有能量效率高、可扩展性好、简单可行的优点,但是分簇算法属于一种模糊定位算法,不具有较高的精度。此外,分簇算法的簇首替换如果在全局范围内进行选择,很容易造成高消耗。AOA(angle of arrival)算法在复杂环境中具有精确的定位能力。文章通过运用AOA测距算法,使分簇算法的每个节点具有自探测能力,通过节点相对夹角,用坐标算法算出相应于簇首的坐标。为了让能量消耗低于普通分簇算法,文章根据完全图中能量有效原理,让分簇只在初始时进行一次,在每个簇内无簇首或能量低时,对簇首进行重选举,再将信息发送给总簇。Matlab仿真实验表明,文章算法实现了range-based的分簇定位算法,且保留了快速部署、能量效率高、高精度的优点。根据实验,文章算法适用于不松散部署的无线传感网络。%Nowadays, network security mostly connects to wireless sensor network (WSN), the ability of WSN rests with the quality of the localization algorithm. Clustering localization algorithm is efifcient, highly scalable, simple and practical algorithm, but it is also a fuzzy match algorithm which does not have high accuracy. If cluster-head switch of clustering algorithm is done within the global nodes, it will cause large amount of energy waste. The AOA algorithm has good localization ability under complex environment. In this paper, by using the AOA algorithm, every node has the ability of self-detection and can calculate the coordinates relative to cluster-head with coordinate algorithm by using node relative-angle. In order to reduce energy waste, this paper designs a algorithm base upon energy-efifcient principle of the complete graph. Separating clusters only runs once

  9. Low-level measuring techniques for neutrons: High accuracy neutron source strength determination and fluence rate measurement at an underground laboratory

    Science.gov (United States)

    Zimbal, Andreas; Degering, Detlev; Reginatto, Marcel; Schuhmacher, Helmut; Wiegel, Burkhard; Zuber, Kai

    2013-08-01

    We report on measuring techniques for neutrons that have been developed at the Physikalisch-Technische Bundesanstalt (PTB), the German National Metrology Institute. PTB has characterized radioactive sources used in the BOREXINO and XENON100 experiments. For the BOREXINO experiment, a 228Th gamma radiation source was required which would not emit more than 10 neutrons per second. The determination of the neutron emission rate of this specially designed 228Th source was challenging due to the low neutron emission rate and because the ratio of neutron to gamma radiation was expected to be extremely low, of the order of 10-6. For the XENON100 detector, PTB carried out a high accuracy measurement of the neutron emission rate of an AmBe source. PTB has also done measurements in underground laboratories. A two month measurement campaign with a set of 3He-filled proportional counters was carried out in PTB's former UDO underground laboratory at the Asse salt mine. The aim of the campaign was to determine the intrinsic background of detectors, which is needed for the analysis of data taken in lowintensity neutron fields. At a later time, PTB did a preliminary measurement of the neutron fluence rate at the underground laboratory Felsenkeller operated by VKTA. By taking into account data from UDO, Felsenkeller, and detector calibrations made at the PTB facility, it was possible to estimate the neutron fluence rate at the Felsenkeller underground laboratory.

  10. Design and integration of a high accuracy multichannel analog CMOS peak detect and hold circuit for APD-based PET imaging.

    Science.gov (United States)

    Fang, Xiaochao; Brasse, David; Hu-Guo, Christine; Hu, Yann

    2012-04-01

    This paper presents the design of a high accuracy multichannel peak detect and hold (PDH) circuit. This PDH measures the energy of an event and is one part of a readout chain for avalanche photo diodes (APD)-based positron emission tomography (PET) imaging. The circuit is designed in a 0.35μm CMOS process. The proposed PDH is dedicated to ultra low amplitude, large amplitude range from several tens millivolts to 1.1 V, and fast peaking time (190 ns) semi-Gaussian pulses. The two-phase technique has been used to cancel the major error source of the classical CMOS PDH: offset. A two-gain OTA is applied to minimize the DC error. A peak error less 1% for a small input signal (amplitude is between 40 mV and 300 mV) and a peak error less than 0.2% for a large input signal (amplitude is between 300 mV and 1.1 V) have been obtained from test. The area of a PDH is equal to about 200 μm × 40 μm. In our PDH system, the drop rate is negligible.

  11. Improving protein identification sensitivity by combining MS and MS/MS information for shotgun proteomics using LTQ-Orbitrap high mass accuracy data.

    Science.gov (United States)

    Lu, Bingwen; Motoyama, Akira; Ruse, Cristian; Venable, John; Yates, John R

    2008-03-15

    We investigated and compared three approaches for shotgun protein identification by combining MS and MS/MS information using LTQ-Orbitrap high mass accuracy data. In the first approach, we employed a unique mass identifier method where MS peaks matched to peptides predicted from proteins identified from an MS/MS database search are first subtracted before using the MS peaks as unique mass identifiers for protein identification. In the second method, we used an accurate mass and time tag method by building a potential mass and retention time database from previous MudPIT analyses. For the third method, we used a peptide mass fingerprinting-like approach in combination with a randomized database for protein identification. We show that we can improve protein identification sensitivity for low-abundance proteins by combining MS and MS/MS information. Furthermore, "one-hit wonders" from MS/MS database searching can be further substantiated by MS information and the approach improves the identification of low-abundance proteins. The advantages and disadvantages for the three approaches are then discussed.

  12. High-Precision Surface Inspection: Uncertainty Evaluation within an Accuracy Range of 15μm with Triangulation-based Laser Line Scanners

    Science.gov (United States)

    Dupuis, Jan; Kuhlmann, Heiner

    2014-06-01

    Triangulation-based range sensors, e.g. laser line scanners, are used for high-precision geometrical acquisition of free-form surfaces, for reverse engineering tasks or quality management. In contrast to classical tactile measuring devices, these scanners generate a great amount of 3D-points in a short period of time and enable the inspection of soft materials. However, for accurate measurements, a number of aspects have to be considered to minimize measurement uncertainties. This study outlines possible sources of uncertainties during the measurement process regarding the scanner warm-up, the impact of laser power and exposure time as well as scanner’s reaction to areas of discontinuity, e.g. edges. All experiments were performed using a fixed scanner position to avoid effects resulting from imaging geometry. The results show a significant dependence of measurement accuracy on the correct adaption of exposure time as a function of surface reflectivity and laser power. Additionally, it is illustrated that surface structure as well as edges can cause significant systematic uncertainties.

  13. High-energy feedback microwave thermotherapy and intraprostatic injections of mepivacaine and adrenaline: an evaluation of calculated cell kill accuracy and responder rate.

    Science.gov (United States)

    Stenmark, Fredrik; Brudin, Lars; Stranne, Johan; Peeker, Ralph

    2014-08-01

    The aim of this study was to evaluate cell kill accuracy and responder rate when using injections of intraprostatic mepivacaine and adrenaline (MA) before high-energy microwave thermotherapy (HE-TUMT). This retrospective evaluation encompassed 283 treatments in men with lower urinary tract symptoms or urinary retention due to benign prostatic hyperplasia. They were treated consecutively during 2003-2008 using HE-TUMT with a feedback technique. Immediately before treatment, MA was administered into the prostate via a Schelin Catheter®. Clinical outcome was evaluated 3 months after treatment using a validated symptom score, transrectal ultrasound, peak urinary flow and postvoid residual. Systematic underestimation of the resulting coagulation necrosis was a consistent finding when using MA, a calculated cell kill of 21% yielding a volume reduction of 26% for prostate volumes less than 100 ml and 31% for prostate volumes greater than or equal to 100 ml. Mean prostate volume was 74 ml and mean treatment time was 13 min. Less than 1% of the patients needed analgesics or sedatives on demand. Analysis of the data showed an estimated clinical responder rate of approximately 87%. The resulting prostate volume reduction corresponds to the earlier empirically recommended 30% cell kill for CoreTherm® without MA. The treatment concept combining CoreTherm with intraprostatic injections of MA corresponds to the clinical outcome of thermotherapy without MA, with the benefits of reduced pain, shortened treatment time and decreased energy consumption.

  14. 高精度曲面建模方法的系统构建%System construction of high accuracy surface modeling

    Institute of Scientific and Technical Information of China (English)

    田会; 张承明; 赵娜; 岳天祥

    2015-01-01

    High Accuracy Surface Modeling method(HASM)is a kind of curved surface modeling method based on the theory of differential geometry surfaces. Large number of numerical tests show that the simulation accuracy of HASM is higher than that of classical interpolation methods such as Kriging, IDW and Spline. And it has been successfully applied to the soil properties surface modeling, the temperature and precipitation, DEM construction and ecosystem changes, etc. Since the current HASM programs are mostly developed by Matlab, C++and Fortran, and it is subjected to the limitations of the development tools, there isn’t a convenient graphical interface for users, which blocks the popularization and applica-tion of the method. To solve this problem, this paper builds the HASM modeling system based on windows forms using Visual Studio as tools with C# language, and makes some numerical tests. The results demonstrate the effectiveness of the system.%高精度曲面建模方法(HASM)是一种基于微分几何学曲面理论的曲面建模方法。大量数值实验表明, HASM的模拟精度高于Kriging、IDW、Spline等经典的插值方法,并已成功应用于土壤属性曲面建模、气温要素、DEM构建及生态系统变化趋势等领域。由于目前的HASM程序大多是用Matlab、C++、Fortran等语言开发的,受开发工具的限制,尚没有便于使用的图形界面,阻碍了方法的推广应用。针对这个问题,利用C#语言,在Visual Studio中构建了基于windows窗体的HASM模型系统,并做了一定的数值测试实验,结果表明了该系统的有效性。

  15. Diagnostic accuracy of high-risk HPV genotyping in women with high-grade cervical lesions: evidence for improving the cervical cancer screening strategy in China.

    Science.gov (United States)

    Xu, Huihui; Lin, Aifen; Shao, Xiujuan; Shi, Weiwu; Zhang, Yang; Yan, Weihua

    2016-12-13

    Currently, clinical data for primary HPV screening alone are lacking in China. Here, we evaluate cervical cancer screening with primary HPV genotyping, as well as possible future screening strategy. Overall, high-risk HPV (hrHPV) prevalence was 18.2% among hospital-based population in Taizhou area. For cervical intraepithelial neoplasia 2 or worse (CIN2+), the sensitivity of primary hrHPV genotyping strategy and current cervical cancer screening strategy were 93.5%, and 71.1%, respectively; whereas the specificity was 17.5%, and 62.4%, respectively. Current cervical screening strategy had slightly higher positive predictive values (28.4%) for CIN2+ than hrHPV genotyping strategy (21.9%), whereas primary hrHPV genotyping strategy demonstrated higher negative predictive values (94.7%) than current cervical screening strategy (91.1%). Compared to HPV35/39/45/51/56/59/66/68 genotypes, the odds ratios (OR) for CIN2+ in HPV16/18/31/33/52/58 infection women were 3.2 (95% confidence interval [CI] 2.3-4.1). Primary hrHPV genotyping strategy provides a better predictive value than HPV16/18 genotyping alone in guiding the clinical management of the current cervical cancer screening. HPV testing without adjunctive cytology may be sufficiently sensitive for primary cervical cancer screening.

  16. Equations of State for Mixtures: Results from DFT Simulations of Xenon/Ethane Mixtures Compared to High Accuracy Validation Experiments on Z

    Science.gov (United States)

    Magyar, Rudolph

    2013-06-01

    We report a computational and validation study of equation of state (EOS) properties of liquid / dense plasma mixtures of xenon and ethane to explore and to illustrate the physics of the molecular scale mixing of light elements with heavy elements. Accurate EOS models are crucial to achieve high-fidelity hydrodynamics simulations of many high-energy-density phenomena such as inertial confinement fusion and strong shock waves. While the EOS is often tabulated for separate species, the equation of state for arbitrary mixtures is generally not available, requiring properties of the mixture to be approximated by combining physical properties of the pure systems. The main goal of this study is to access how accurate this approximation is under shock conditions. Density functional theory molecular dynamics (DFT-MD) at elevated-temperature and pressure is used to assess the thermodynamics of the xenon-ethane mixture. The simulations are unbiased as to elemental species and therefore provide comparable accuracy when describing total energies, pressures, and other physical properties of mixtures as they do for pure systems. In addition, we have performed shock compression experiments using the Sandia Z-accelerator on pure xenon, ethane, and various mixture ratios thereof. The Hugoniot results are compared to the DFT-MD results and the predictions of different rules for combing EOS tables. The DFT-based simulation results compare well with the experimental points, and it is found that a mixing rule based on pressure equilibration performs reliably well for the mixtures considered. Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000.

  17. Density-Functional Theory with Dispersion-Correcting Potentials for Methane: Bridging the Efficiency and Accuracy Gap between High-Level Wave Function and Classical Molecular Mechanics Methods.

    Science.gov (United States)

    Torres, Edmanuel; DiLabio, Gino A

    2013-08-13

    Large clusters of noncovalently bonded molecules can only be efficiently modeled by classical mechanics simulations. One prominent challenge associated with this approach is obtaining force-field parameters that accurately describe noncovalent interactions. High-level correlated wave function methods, such as CCSD(T), are capable of correctly predicting noncovalent interactions, and are widely used to produce reference data. However, high-level correlated methods are generally too computationally costly to generate the critical reference data required for good force-field parameter development. In this work we present an approach to generate Lennard-Jones force-field parameters to accurately account for noncovalent interactions. We propose the use of a computational step that is intermediate to CCSD(T) and classical molecular mechanics, that can bridge the accuracy and computational efficiency gap between them, and demonstrate the efficacy of our approach with methane clusters. On the basis of CCSD(T)-level binding energy data for a small set of methane clusters, we develop methane-specific, atom-centered, dispersion-correcting potentials (DCPs) for use with the PBE0 density-functional and 6-31+G(d,p) basis sets. We then use the PBE0-DCP approach to compute a detailed map of the interaction forces associated with the removal of a single methane molecule from a cluster of eight methane molecules and use this map to optimize the Lennard-Jones parameters for methane. The quality of the binding energies obtained by the Lennard-Jones parameters we obtained is assessed on a set of methane clusters containing from 2 to 40 molecules. Our Lennard-Jones parameters, used in combination with the intramolecular parameters of the CHARMM force field, are found to closely reproduce the results of our dispersion-corrected density-functional calculations. The approach outlined can be used to develop Lennard-Jones parameters for any kind of molecular system.

  18. Design of Programmable Control Current Source with High Accuracy%高精度程控电流源的设计

    Institute of Scientific and Technical Information of China (English)

    王丽; 康红明; 谢东岩

    2012-01-01

    采用ADuC812单片机作为整机的控制单元,通过软件和外围电路设计,使程控直流电流源具备实时检测实际输出电流值的功能,并通过采样将实际输出反馈到单片机中,单片机对数据进行分析、处理后再重新调整D/A输出的值,从而达到稳流的目的.所设计的电流源还具有电流可预置、可步进调整以及可同时显示电流预置值和实测值等功能.该系统具有结构简单、工作稳定、纹波电流小、控制精度高、成本低廉、实用性强的特点.%The programmable control DC current source based on a single-chip microcomputer ADuC812 was designed,and the hardware structure and software program was introduced. The current source can measure actual output current,and output signal of (he current can be fed back to the single-chip microcomputer through the sampling at the same time. The single-chip microcomputer readjusts output value of D/A after data analysis to stabilize current. The current source, realized that the current can be set and adjusted step by step,and the steppoint value and actual measurement value can be displayed at the same time. The system is characterized by simple structure,good stability,low ripple current,high accuracy of control,low cost and high practical value.

  19. Social Power Increases Interoceptive Accuracy

    Directory of Open Access Journals (Sweden)

    Mehrad Moeini-Jazani

    2017-08-01

    Full Text Available Building on recent psychological research showing that power increases self-focused attention, we propose that having power increases accuracy in perception of bodily signals, a phenomenon known as interoceptive accuracy. Consistent with our proposition, participants in a high-power experimental condition outperformed those in the control and low-power conditions in the Schandry heartbeat-detection task. We demonstrate that the effect of power on interoceptive accuracy is not explained by participants’ physiological arousal, affective state, or general intention for accuracy. Rather, consistent with our reasoning that experiencing power shifts attentional resources inward, we show that the effect of power on interoceptive accuracy is dependent on individuals’ chronic tendency to focus on their internal sensations. Moreover, we demonstrate that individuals’ chronic sense of power also predicts interoceptive accuracy similar to, and independent of, how their situationally induced feeling of power does. We therefore provide further support on the relation between power and enhanced perception of bodily signals. Our findings offer a novel perspective–a psychophysiological account–on how power might affect judgments and behavior. We highlight and discuss some of these intriguing possibilities for future research.

  20. The Glacier and Ice Sheet Topography Interferometer: An Update on a Unique Sensor for High Accuracy Swath Mapping of Land Ice

    Science.gov (United States)

    Moller, D.; Heavey, B.; Hensley, S.; Hodges, R.; Rengarajan, S.; Rignot, E.; Sadowy, G.; Simard, M.; Zawadzki, M.

    2007-12-01

    We discuss the innovative concept and technology development of a Ka-band (35 GHz) radar for mapping the surface topography of glaciers and ice sheets. The "Glacier and Land Ice Surface Topography Interferometer" (GLISTIN) is a single-pass, single platform interferometric synthetic aperture radar (InSAR) with an 8mm wavelength, which minimizes snow penetration yet remains relatively impervious to atmospheric attenuation. Such a system has the potential for delivering topographic maps at high spatial resolution, high vertical accuracy, independent of cloud cover, with a subseasonal update and would greatly enhance current observational and modeling capabilities of ice mass-balance and glacial retreat. To enable such measurements, a digitally beamformed antenna array is utilized to provide a wide measurement swath at a technologically feasible transmit power. To prove this concept and advance the technology readiness of this design we are currently funded by the NASA Earth Science Technology Office (ESTO) Instrument Incubator Program (IIP) to build and test a 1m x 1m digitally-beamformed (DBF) Ka-band slotted waveguide antenna with integrated digital receivers. This antenna provides 16 simultaneous receive beams, effectively broadening the swath without reducing receive antenna gain. The implementation of such a large aperture at Ka-band presents many design, manufacturing and calibration challenges which are addressed as part of this IIP. The integrated DBF array will be fielded at the Jet Propulsion Laboratory's antenna range to demonstrate the overall calibration, beamforming and interferometric performance through creation of topographic imagery of the local Arroyo Seco. Currently entering the third year of the program, we will overview the system concept, array implementation and status of the technology. While the IIP addresses the development of the major technology challenges, an additional effort will demonstrate the phenomenology of the measurement by

  1. Target Price Accuracy

    Directory of Open Access Journals (Sweden)

    Alexander G. Kerl

    2011-04-01

    Full Text Available This study analyzes the accuracy of forecasted target prices within analysts’ reports. We compute a measure for target price forecast accuracy that evaluates the ability of analysts to exactly forecast the ex-ante (unknown 12-month stock price. Furthermore, we determine factors that explain this accuracy. Target price accuracy is negatively related to analyst-specific optimism and stock-specific risk (measured by volatility and price-to-book ratio. However, target price accuracy is positively related to the level of detail of each report, company size and the reputation of the investment bank. The potential conflicts of interests between an analyst and a covered company do not bias forecast accuracy.

  2. Rethinking Empathic Accuracy

    OpenAIRE

    Meadors, Joshua

    2014-01-01

    The present study is a methodological examination of the implicit empathic accuracy measure introduced by Zaki, Ochsner, and Bolger (2008). Empathic accuracy (EA) is defined as the ability to understand another person's thoughts and feelings (Ickes, 1993). Because this definition is similar to definitions of cognitive empathy (e.g., Shamay-Tsoory, 2011) and because affective empathy does not appear to be related to empathic accuracy (Zaki et al., 2008), the Basic Empathy Scale--which measures...

  3. High Dose MicroCT Does Not Contribute Toward Improved MicroPET/CT Image Quantitative Accuracy and Can Limit Longitudinal Scanning of Small Animals

    Directory of Open Access Journals (Sweden)

    Wendy A. McDougald

    2017-10-01

    Full Text Available Obtaining accurate quantitative measurements in preclinical Positron Emission Tomography/Computed Tomography (PET/CT imaging is of paramount importance in biomedical research and helps supporting efficient translation of preclinical results to the clinic. The purpose of this study was two-fold: (1 to investigate the effects of different CT acquisition protocols on PET/CT image quality and data quantification; and (2 to evaluate the absorbed dose associated with varying CT parameters.Methods: An air/water quality control CT phantom, tissue equivalent material phantom, an in-house 3D printed phantom and an image quality PET/CT phantom were imaged using a Mediso nanoPET/CT scanner. Collected data was analyzed using PMOD software, VivoQuant software and National Electric Manufactures Association (NEMA software implemented by Mediso. Measured Hounsfield Unit (HU in collected CT images were compared to the known HU values and image noise was quantified. PET recovery coefficients (RC, uniformity and quantitative bias were also measured.Results: Only less than 2 and 1% of CT acquisition protocols yielded water HU values < −80 and air HU values < −840, respectively. Four out of 11 CT protocols resulted in more than 100 mGy absorbed dose. Different CT protocols did not impact PET uniformity and RC, and resulted in <4% overall bias relative to expected radioactive concentration.Conclusion: Preclinical CT protocols with increased exposure times can result in high absorbed doses to the small animals. These should be avoided, as they do not contributed toward improved microPET/CT image quantitative accuracy and could limit longitudinal scanning of small animals.

  4. Improving the diagnostic accuracy of acute myocardial infarction with the use of high-sensitive cardiac troponin T in different chronic kidney disease stages

    Science.gov (United States)

    Yang, Hongliu; Liu, Jing; Luo, Han; Zeng, Xiaoxi; Tang, Xi; Ma, Liang; Mai, Hongxia; Gou, Shenju; Liu, Fang; Fu, Ping

    2017-01-01

    High-sensitive cardiac troponin T (hs-TnT) is a critical biomarker in diagnosis of acute myocardial infarction (AMI). However, CKD individuals usually have elevated hs-TnT even in the absence of AMI. Our study aimed to explore the optimal cutoff-value of hs-TnT and further to improve diagnostic accuracy of AMI in CKD patients. Clinical data of 489 patients were collected from the maintained database between September 2010 and June 2014. CKD patients with AMI were assigned to CKD+AMI group and CKD patients without AMI were assigned to CKD group. Receiver operating characteristic curves were utilized to derive the optimal cutoff-value. In CKD+STEMI and CKD group, hs-TnT was increased with descending eGFR. In CKD+NSTEMI group, hs-TnT showed an upward trend with increasing SYNTAX Score. In patients with CKD+STEMI, hs-TnT was significantly correlated with SYNTAX Score in CKD stage 2, stage 4 and in total. In CKD patients, the optimal cutoff-value of hs-TnT for diagnosis of AMI was 129.45 ng/l with 75.2% sensitivity and 83.2% specificity. The cutoff-value appeared to be hs-TnT level of 99.55ng/l in CKD stage 3, 129.45 ng/l in CKD stage 4, 105.50 ng/l in CKD stage 5 and 149.35 ng/l in dialysis patients, respectively. In different stages of CKD, eGFR-range-specific optimal cutoff-values should be considered. PMID:28145489

  5. 新型高准确度分光光度计的设计与测试%Design and testing of high-accuracy spectrophotometer

    Institute of Scientific and Technical Information of China (English)

    周磊; 郑小兵

    2008-01-01

    Interference filters are used in many fields,such as radiometric and photometric measurements and so on.For high-accuracy measurement of spectral transmittance of interference filter,an automated,single-beam spectrophotometer based on DK242 double monochromator is developed,whose input optics and output optics are designed independently.In order to improve the accuracv of measurement,the averaging detector unit with a silicon detector is introduced into the measurement system.The source of the uncertainties includes wavelength calibration,detector nonlinearity,systcminstability,beam displacement and so on.A total uncertainty of 8.78x10-3is estinlated for transmittance measurements of interference filters,which meets the requirement of the design.%目前,干涉滤光片已广泛运用到辐射度学测量、光度学测量等领域,为保证其光谱透过率测量的高准确度,提出了采用基于DK242单色仪,入射、出射光路独立设计的全自动,单光路分光光度计,其测量部分采用了硅探测器与积分球组合的探测单元,提高了测量的准确度.装置的不确定度源包括波长定标、探测器均匀性、系统稳定性、光束移位等,装置整体不确定度达到8.78×10-3,满足设计要求.

  6. Low power and high accuracy spike sorting microprocessor with on-line interpolation and re-alignment in 90 nm CMOS process.

    Science.gov (United States)

    Chen, Tung-Chien; Ma, Tsung-Chuan; Chen, Yun-Yu; Chen, Liang-Gee

    2012-01-01

    Accurate spike sorting is an important issue for neuroscientific and neuroprosthetic applications. The sorting of spikes depends on the features extracted from the neural waveforms, and a better sorting performance usually comes with a higher sampling rate (SR). However for the long duration experiments on free-moving subjects, the miniaturized and wireless neural recording ICs are the current trend, and the compromise on sorting accuracy is usually made by a lower SR for the lower power consumption. In this paper, we implement an on-chip spike sorting processor with integrated interpolation hardware in order to improve the performance in terms of power versus accuracy. According to the fabrication results in 90nm process, if the interpolation is appropriately performed during the spike sorting, the system operated at the SR of 12.5 k samples per second (sps) can outperform the one not having interpolation at 25 ksps on both accuracy and power.

  7. Developing of the New Type High Accuracy Airborne Gravimetry System%新型高精度航空重力勘察系统研制

    Institute of Scientific and Technical Information of China (English)

    吴美平; 张开东; 曹聚亮; 洪华杰; 周锡华

    2016-01-01

    10 years. Through the rearch work in “11.5” , National University of Defense Technology(NUDT) had accumulated much experience on the hardware design, software desigh, system integration, data processing and applications of strapdown gravimetry, the principle prototype designed by NUDT has rearched the advanced level among the same type gravimeters. The goals of this project include that breaking through the key technologies restricted the high accuracy gravimetry, and developing the airborne gravimetry system that can meet the requirement of the reconnaissance of oil and mine, and the accuracy reaching the advanced level of commercial products. The anticipate accuracy is better than 1mGal at the resolution of 3km, and we also need to fullfill demonstrate production more than 100,000km. This report introduced the background of the project, foundation, and the scheme to realize the goal.

  8. The Effects of Contingent Praise Upon the Achievement of a Deficit Junior High School Student in Oral Reading Accuracy in Probes Above Her Functional Grade Level.

    Science.gov (United States)

    Proe, Susan; Wade, David

    Evaluated was the effectiveness of three training procedures (imitation training, imitation training with praise, and imitation training with points for an art supply contingency) in improving the oral reading accuracy and reading comprehension of a 13-year-old girl whose functional reading was at the second grade level. The procedures were…

  9. Patient-specific geometrical modeling of orthopedic structures with high efficiency and accuracy for finite element modeling and 3D printing.

    Science.gov (United States)

    Huang, Huajun; Xiang, Chunling; Zeng, Canjun; Ouyang, Hanbin; Wong, Kelvin Kian Loong; Huang, Wenhua

    2015-12-01

    structures with less operating time and high accuracy of modeling.

  10. CADASTRAL DATABASE POSITIONAL ACCURACY IMPROVEMENT

    Directory of Open Access Journals (Sweden)

    N. M. Hashim

    2017-10-01

    Full Text Available Positional Accuracy Improvement (PAI is the refining process of the geometry feature in a geospatial dataset to improve its actual position. This actual position relates to the absolute position in specific coordinate system and the relation to the neighborhood features. With the growth of spatial based technology especially Geographical Information System (GIS and Global Navigation Satellite System (GNSS, the PAI campaign is inevitable especially to the legacy cadastral database. Integration of legacy dataset and higher accuracy dataset like GNSS observation is a potential solution for improving the legacy dataset. However, by merely integrating both datasets will lead to a distortion of the relative geometry. The improved dataset should be further treated to minimize inherent errors and fitting to the new accurate dataset. The main focus of this study is to describe a method of angular based Least Square Adjustment (LSA for PAI process of legacy dataset. The existing high accuracy dataset known as National Digital Cadastral Database (NDCDB is then used as bench mark to validate the results. It was found that the propose technique is highly possible for positional accuracy improvement of legacy spatial datasets.

  11. Accuracy of Sphygmomanometers

    OpenAIRE

    Basak, Okay

    2014-01-01

    One of the factors affecting the accuracy of readings of blood pressure is the equipment used. Defects or inaccuracy of aneroid sphygmomanometers may be source of error in blood pressure measurement. We inspected 100 sphygmomanometers for physical defects and assessed their accuracy against a standard mercury manometer at four different pressure points. 46 of the 100 sphygmomanometers were determined to be intolerant (deviation from the mercury manometer by greater than±3 mm Hg at two or more...

  12. Image quality, radiation dose, and diagnostic accuracy of prospectively ECG-triggered high-pitch coronary CT angiography at 70 kVp in a clinical setting: comparison with invasive coronary angiography

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Long Jiang; Qi, Li; Zhou, Chang Sheng; Zhao, Yan E.; Li, Xie; Lu, Guang Ming [Jinling Hospital, Medical School of Nanjing University, Department of Medical Imaging, Nanjing, Jiangsu (China); Wang, Yining; Cao, Jian; Jin, Zhengyu [Peking Union Medical College Hospital, Department of Radiology, Beijing (China); Schoepf, U.J. [Jinling Hospital, Medical School of Nanjing University, Department of Medical Imaging, Nanjing, Jiangsu (China); Medical University of South Carolina, Division of Cardiovascular Imaging, Charleston, SC (United States); Meinel, Felix G. [Medical University of South Carolina, Division of Cardiovascular Imaging, Charleston, SC (United States); Ludwig-Maximilians-University Hospital, Institute for Clinical Radiology, Munich (Germany); Bayer, Richard R. [Medical University of South Carolina, Division of Cardiovascular Imaging, Charleston, SC (United States); Gong, Jian Bin [Jinling Hospital, Medical School of Nanjing University, Department of Cardiology, Nanjing, Jiangsu (China)

    2016-03-15

    To investigate image quality, radiation dose, and diagnostic performance of prospectively ECG-triggered high-pitch coronary CT angiography (CCTA) at 70 kVp compared to invasive coronary angiography (ICA) as reference standard. Forty-three patients underwent prospectively ECG-triggered high-pitch CCTA at 70 kVp using 30 cc (11 g iodine) contrast medium and ICA. Subjective and objective image quality was evaluated for each CCTA study. CCTA performance for diagnosing ≥50 % stenosis was assessed. Results were stratified according to heart rate (HR), body mass index (BMI), Agatston score, and image quality. At CCTA, 94.3 % (500/530) of coronary segments were of diagnostic quality. Using ICA as reference standard, sensitivity and accuracy were 100 % and 93.0 % on a per-patient basis. Per-vessel and per-segment performances were 92.2 % and 89.5 %; 79.5 % and 88.3 %, respectively. No differences were found in diagnostic accuracy between different HR, BMI, and calcification subgroups (all P > 0.05) on a per-patient basis. However, low image quality reduced diagnostic accuracy on a per-patient, per-vessel and per-segment basis (all P < 0.05). The mean effective radiation dose was 0.2 ± 0.0 mSv. Our presented protocol results in an effective radiation dose of 0.2 mSv and high diagnostic accuracy for stenosis detection in a selected, non-obese population. (orig.)

  13. Accounting of fundamental components of the rotation parameters of the Earth in the formation of a high-accuracy orbit of navigation satellites

    Science.gov (United States)

    Markov, Yu. G.; Mikhailov, M. V.; Pochukaev, V. N.

    2012-07-01

    An analysis of perturbing factors influencing the motion of a navigation satellite (NS) is carried out, and the degree of influence of each factor on the GLONASS orbit is estimated. It is found that fundamental components of the Earth's rotation parameters (ERP) are one substantial factor commensurable with maximum perturbations. Algorithms for the calculation of orbital perturbations caused by these parameters are given; these algorithms can be implemented in a consumer's equipment. The daily prediction of NS coordinates is performed on the basis of real GLONASS satellite ephemerides transmitted to a consumer, using the developed prediction algorithms taking the ERP into account. The obtained accuracy of the daily prediction of GLONASS ephemerides exceeds by tens of times the accuracy of the daily prediction performed using algorithms recommended in interface control documents.

  14. The structure characteristic and technical performance of high accuracy twin spindle turning-milling center%一种精密双主轴车铣中心的结构特点与技术性能

    Institute of Scientific and Technical Information of China (English)

    李林; 陈梅

    2013-01-01

    研制了一种高精度、高速度、高柔性等特点的六轴四联动的双主轴车铣中心,介绍机床的总体结构布局,主要机械结构、特点、技术参数.该机床是解决高精度复杂回转零件加工的理想设备.%This paper introduces six axes with four axes simultaneous motion twin spindle turning-milling center with the characteristic of high accuracy, high speed and high flexibility, describes the total structural arrangement , the main mechanical structure, characteristic and the main technical data of the machine. This machine is a ideal equipment for machining the complex turn round spares with high accuracy.

  15. Research of annealing mode for high accuracy stamped parts production from titanium alloy 83Ti-5Al-5Cr-5Mo after tooling

    Science.gov (United States)

    Balaykin, A. V.; Nosova, E. A.; Galkina, N. V.

    2016-11-01

    The aim of the work is to solve question of accuracy increase in tolled and annealed parts made from forged rod of titanium alloy. Plate pieces were cut from cross-section, annealed at 800°C during 1, 2, 3, 4 and 5 hours. The criterion combining minimum bending radius and spring back angle was found. This criterion shows the maximum values after tooling and annealing for 3 hours.

  16. Assessing the Accuracy of High Resolution Digital Surface Models Computed by PhotoScan ® and MicMac ® in Sub-Optimal Survey Conditions

    OpenAIRE

    Marion Jaud; Sophie Passot; Réjanne Le Bivic; Christophe Delacourt; Philippe Grandjean; Nicolas Le Dantec

    2016-01-01

    International audience; For monitoring purposes and in the context of geomorphological research, Unmanned Aerial Vehicles (UAV) appear to be a promising solution to provide multi-temporal Digital Surface Models (DSMs) and orthophotographs. There are a variety of photogrammetric software tools available for UAV-based data. The objective of this study is to investigate the level of accuracy that can be achieved using two of these software tools: Agisoft PhotoScan ® Pro and an open-source altern...

  17. Long Latency and High Variability in Accuracy-Speed of Prosaccades in Alzheimer’s Disease at Mild to Moderate Stage

    Directory of Open Access Journals (Sweden)

    Qing Yang

    2011-10-01

    Full Text Available Background: Studying saccades is a useful tool to investigate brain function. There is still controversy regarding deficits in prosaccades in Alzheimer’s disease (AD, and a study of saccades in subjects with mild cognitive impairment (MCI has not been published to date. Methods: We examined horizontal saccades in 10 healthy elderly, and 9 MCI and 9 AD patients. Two tasks were used: gap (fixation target extinguishes prior to target onset and overlap (fixation stays on after target onset. Eye movements were recorded with the Skalar IRIS system. Results: (1 Latencies were shorter in the gap than in the overlap task (a gap effect in all three groups of subjects: healthy elderly, MCI and AD; (2 for both tasks, latency of saccades was longer for AD patients than for healthy and MCI subjects, and (3 accuracy and mean velocity were normal in MCI and AD subjects, however, variability in accuracy-speed was higher for AD patients than for healthy and MCI subjects in the overlap task. Conclusions: Abnormalities in reaction time and accuracy-speed variability reflect deficits in cerebral areas involved in the triggering and execution of saccades; a saccade test can be useful to follow up the evolution of MCI subjects as some of them may develop AD disease.

  18. Accuracy, image quality and radiation dose comparison of high-pitch spiral and sequential acquisition on 128-slice dual-source CT angiography in children with congenital heart disease

    Energy Technology Data Exchange (ETDEWEB)

    Nie, Pei; Wang, Ximing; Cheng, Zhaoping; Ji, Xiaopeng; Duan, Yanhua [Shandong University, Shandong Provincial Key Laboratory of Diagnosis and Treatment of Cardio-cerebral Vascular Diseases, Shandong Medical Imaging Research Institute, Jinan, Shandong (China); Chen, Jiuhong [CT Research Collaboration, Siemens Ltd. China, Beijing (China)

    2012-10-15

    To compare accuracy, image quality and radiation dose between high-pitch spiral and sequential modes on 128-slice dual-source computed tomographic (DSCT) angiography in children with congenital heart disease (CHD). Forty patients suspected with CHD underwent 128-slice DSCT angiography with high-pitch mode and sequential mode respectively. All the anomalies were confirmed by the surgical and/or the conventional cardiac angiography (CCA) findings. The diagnostic accuracy, the subjective and objective image quality and effective radiation doses were compared. There was no significant difference in diagnostic accuracy ({chi}{sup 2} = 0.963, P > 0.05), the objective parameters for image quality (P > 0.05) and the image quality of great vessels (u = 167.500, P > 0.05) between the two groups. The image quality of intracardiac structures and coronary arteries was significantly better in the sequential mode group than that in the high-pitch group (u = 112.500 and 100.000, P < 0.05). The mean effective dose in high-pitch group (0.17 {+-} 0.05 mSv) was significantly lower (t = 5.287, P < 0.05) than that in the sequential mode group (0.29 {+-} 0.09 mSv). Both the high-pitch and the sequential modes for 128-slice DSCT angiography provide high accuracy for the assessment of CHD in children, while the high-pitch mode, even with some image quality decrease, further significantly lowers the radiation dose. (orig.)

  19. 关于高精度12参矩形板元的分析%Analysis on a Set of 12-parameter Rectangular Plate Element with High Accuracy

    Institute of Scientific and Technical Information of China (English)

    石东洋; 王彩霞

    2006-01-01

    It is proved that the so-called a set of 12-parameter rectangular plate elements with high accuracy constructed by using double set parameter method and undetermined method are, in fact, the same one; the real shape function space is nothing but the Adini's element's, which has nothing to do with the other high degree terms and leads to a new method for constructing the high accuracy plate elements. This fact has never been seen for other conventional and unconventional, conforming and nonconforming rectangular plate elements, such as Quasi-conforming elements, generalized conforming elements and other double set parameter finite elements. Moreover, such kind of rectangular elements can not be constructed by the conventional finite element methods.

  20. Interview accuracy in partial epilepsy.

    Science.gov (United States)

    Besocke, Ana Gabriela; Rojas, Juan Ignacio; Valiensi, Stella Maris; Cristiano, Edgardo; Garcia, María del Carmen

    2009-11-01

    The statistical concept of accuracy has never been applied to verify the history data collected on seizure disorders by open format interview. We compared patients'/witnesses' descriptions of epileptic seizures with videotaped seizure characteristics and analyzed the accuracy (ACC), sensitivity (SN), specificity (SP), false-positive rate (FPR), and false-negative rate (FNR) of various components of the semiology in patients with partial epilepsy. Language disturbances, complex automatisms, and autonomic signs have high ACC and intermediate FNRs. This means that these manifestations are most obvious to the witness/patient and, therefore, are memorized easily. Dystonic posturing and upper limb automatisms have the highest FNRs, leading to low ACC. These are very subtle signs, not vigorous enough to be paid attention to, but their predictive value in partial epilepsy syndromes is relatively high. We believe these signs need to be directly sought in the interview, because often the patient/witness pays limited attention to them.

  1. Same-day diagnosis based on histology for women suspected of breast cancer: high diagnostic accuracy and favorable impact on the patient.

    Directory of Open Access Journals (Sweden)

    Maarten W Barentsz

    Full Text Available Same-day diagnosis based on histology is increasingly being offered to patients suspected of breast cancer. We evaluated to which extent same-day diagnosis affected diagnostic accuracy and patients' anxiety levels during the diagnostic phase.All 759 women referred for same-day evaluation of suspicious breast lesions between November 2011-March 2013 were included. Diagnostic accuracy was assessed by linking all patients to the national pathology database to identify diagnostic discrepancies, in which case slides were reviewed. Patients' anxiety was measured in 127 patients by the State Trait and Anxiety Inventory on six moments during the diagnostic workup and changes over time (< = 1 week were analyzed by mixed effect models.Core-needle biopsy was indicated in 374/759 patients (49.3% and in 205/759 (27% patients, invasive or in situ cancer was found. Final diagnosis on the same day was provided for 606/759 (79.8% patients. Overall, 3/759 (0.4% discordant findings were identified. Anxiety levels decreased significantly over time from 45.2 to 30.0 (P = <0.001. Anxiety levels decreased from 44.4 to 25.9 (P = <0.001 for patients with benign disease, and remained unchanged for patients diagnosed with malignancies (48.6 to 46.7, P = 0.933. Time trends in anxiety were not affected by other patient or disease characteristics like age, education level or (family history of breast cancer.Same-day histological diagnosis is feasible in the vast majority of patients, without impairing diagnostic accuracy. Patients' anxiety rapidly decreased in patients with a benign diagnosis and remained constant in patients with malignancy.

  2. The accuracy of the crystal chemical parameters at high-pressure conditions from single-crystal X-ray diffraction in diamond-anvil cell

    DEFF Research Database (Denmark)

    Periotto, Benedetta

    applications also in the materials science as it can provide useful information about the properties and performance of new materials. Over the past decades, the research in this field has been strongly developed due to the advances in computer capabilities and to the technological improvements of X...... are important components of the Earth’s lower crust and upper mantle. In the last part of the thesis, the berthierite sulfosalt (FeSb2S4) was measured under pressure in order to test the data accuracy on a slightly more complicated structure...

  3. Assessing the Accuracy of High Resolution Digital Surface Models Computed by PhotoScan® and MicMac® in Sub-Optimal Survey Conditions

    OpenAIRE

    Marion Jaud; Sophie Passot; Réjanne Le Bivic; Christophe Delacourt; Philippe Grandjean; Nicolas Le Dantec

    2016-01-01

    For monitoring purposes and in the context of geomorphological research, Unmanned Aerial Vehicles (UAV) appear to be a promising solution to provide multi-temporal Digital Surface Models (DSMs) and orthophotographs. There are a variety of photogrammetric software tools available for UAV-based data. The objective of this study is to investigate the level of accuracy that can be achieved using two of these software tools: Agisoft PhotoScan® Pro and an open-source alternative, IGN© MicMac®, in s...

  4. Evaluating Measurement Accuracy

    CERN Document Server

    Rabinovich, Semyon G

    2010-01-01

    The goal of Evaluating Measurement Accuracy: A Practical Approach is to present methods for estimating the accuracy of measurements performed in industry, trade, and scientific research. Although multiple measurements are the focus of current theory, single measurements are the ones most commonly used. This book answers fundamental questions not addressed by present theory, such as how to discover the complete uncertainty of a measurement result. In developing a general theory of processing experimental data, this book, for the first time, presents the postulates of the theory of measurements. It introduces several new terms and definitions about the relationship between the accuracy of measuring instruments and measurements utilizing these instruments. It also offers well-grounded and practical methods for combining the components of measurement inaccuracy. From developing the theory of indirect measurements to proposing new methods of reduction in place of the traditional ones, this work encompasses the ful...

  5. SU-E-J-03: Characterization of the Precision and Accuracy of a New, Preclinical, MRI-Guided Focused Ultrasound System for Image-Guided Interventions in Small-Bore, High-Field Magnets

    Energy Technology Data Exchange (ETDEWEB)

    Ellens, N [Johns Hopkins University, Baltimore, Maryland (United States); Farahani, K [National Cancer Institute, Bethesda, MD (United States)

    2015-06-15

    Purpose: MRI-guided focused ultrasound (MRgFUS) has many potential and realized applications including controlled heating and localized drug delivery. The development of many of these applications requires extensive preclinical work, much of it in small animal models. The goal of this study is to characterize the spatial targeting accuracy and reproducibility of a preclinical high field MRgFUS system for thermal ablation and drug delivery applications. Methods: The RK300 (FUS Instruments, Toronto, Canada) is a motorized, 2-axis FUS positioning system suitable for small bore (72 mm), high-field MRI systems. The accuracy of the system was assessed in three ways. First, the precision of the system was assessed by sonicating regular grids of 5 mm squares on polystyrene plates and comparing the resulting focal dimples to the intended pattern, thereby assessing the reproducibility and precision of the motion control alone. Second, the targeting accuracy was assessed by imaging a polystyrene plate with randomly drilled holes and replicating the hole pattern by sonicating the observed hole locations on intact polystyrene plates and comparing the results. Third, the practicallyrealizable accuracy and precision were assessed by comparing the locations of transcranial, FUS-induced blood-brain-barrier disruption (BBBD) (observed through Gadolinium enhancement) to the intended targets in a retrospective analysis of animals sonicated for other experiments. Results: The evenly-spaced grids indicated that the precision was 0.11 +/− 0.05 mm. When image-guidance was included by targeting random locations, the accuracy was 0.5 +/− 0.2 mm. The effective accuracy in the four rodent brains assessed was 0.8 +/− 0.6 mm. In all cases, the error appeared normally distributed (p<0.05) in both orthogonal axes, though the left/right error was systematically greater than the superior/inferior error. Conclusions: The targeting accuracy of this device is sub-millimeter, suitable for many

  6. The Truth about Accuracy

    NARCIS (Netherlands)

    Buekens, F.A.I.; Truyen, Frederick; Martini, Carlo; Boumans, Marcel

    2014-01-01

    When we evaluate the outcomes of investigative actions as justified or unjustified, good or bad, rational or irrational, we make, in a broad sense of the term, evaluative judgements about them. We look at operational accuracy as a desirable and evaluable quality of the outcomes and explore how the c

  7. High-accuracy and real-time 3D positioning, tracking system for medical imaging applications based on 3D digital image correlation

    Science.gov (United States)

    Xue, Yuan; Cheng, Teng; Xu, Xiaohai; Gao, Zeren; Li, Qianqian; Liu, Xiaojing; Wang, Xing; Song, Rui; Ju, Xiangyang; Zhang, Qingchuan

    2017-01-01

    This paper presents a system for positioning markers and tracking the pose of a rigid object with 6 degrees of freedom in real-time using 3D digital image correlation, with two examples for medical imaging applications. Traditional DIC method was improved to meet the requirements of the real-time by simplifying the computations of integral pixel search. Experiments were carried out and the results indicated that the new method improved the computational efficiency by about 4-10 times in comparison with the traditional DIC method. The system was aimed for orthognathic surgery navigation in order to track the maxilla segment after LeFort I osteotomy. Experiments showed noise for the static point was at the level of 10-3 mm and the measurement accuracy was 0.009 mm. The system was demonstrated on skin surface shape evaluation of a hand for finger stretching exercises, which indicated a great potential on tracking muscle and skin movements.

  8. An investigation into the accuracy, stability and parallel performance of a highly stable explicit technique for stiff reaction-transport PDEs

    Energy Technology Data Exchange (ETDEWEB)

    Franz, A., LLNL

    1998-02-17

    The numerical simulation of chemically reacting flows is a topic, that has attracted a great deal of current research At the heart of numerical reactive flow simulations are large sets of coupled, nonlinear Partial Differential Equations (PDES). Due to the stiffness that is usually present, explicit time differencing schemes are not used despite their inherent simplicity and efficiency on parallel and vector machines, since these schemes require prohibitively small numerical stepsizes. Implicit time differencing schemes, although possessing good stability characteristics, introduce a great deal of computational overhead necessary to solve the simultaneous algebraic system at each timestep. This thesis examines an algorithm based on a preconditioned time differencing scheme. The algorithm is explicit and permits a large stable time step. An investigation of the algorithm`s accuracy, stability and performance on a parallel architecture is presented

  9. Note: Optical and electronic design of an amplitude-modulated continuous-wave laser scanner for high-accuracy distance measurement.

    Science.gov (United States)

    Jang, Junhwan; Hwang, Sungui; Park, Kyihwan

    2015-04-01

    To utilize a time-of-flight-based laser scanner as a distance measurement sensor, the measurable distance and accuracy are the most important performance parameters to consider. For these purposes, the optical system and electronic signal processing of the laser scanner should be optimally designed in order to reduce a distance error caused by the optical crosstalk and wide dynamic range input. Optical system design for removing optical crosstalk problem is proposed in this work. Intensity control is also considered to solve the problem of a phase-shift variation in the signal processing circuit caused by object reflectivity. The experimental results for optical system and signal processing design are performed using 3D measurements.

  10. Note: Optical and electronic design of an amplitude-modulated continuous-wave laser scanner for high-accuracy distance measurement

    Energy Technology Data Exchange (ETDEWEB)

    Jang, Junhwan; Hwang, Sungui; Park, Kyihwan, E-mail: khpark@gist.ac.kr [School of Mechatronics, Gwangju Institute of Science and Technology, 123 Cheomdangwagi-ro, Buk-gu, Gwangju (Korea, Republic of)

    2015-04-15

    To utilize a time-of-flight-based laser scanner as a distance measurement sensor, the measurable distance and accuracy are the most important performance parameters to consider. For these purposes, the optical system and electronic signal processing of the laser scanner should be optimally designed in order to reduce a distance error caused by the optical crosstalk and wide dynamic range input. Optical system design for removing optical crosstalk problem is proposed in this work. Intensity control is also considered to solve the problem of a phase-shift variation in the signal processing circuit caused by object reflectivity. The experimental results for optical system and signal processing design are performed using 3D measurements.

  11. The Development of HMS125p 4-axis Linkage High-accuracy Horizontal Machining Center%HMS125p型四轴联动精密卧式加工中心的研制

    Institute of Scientific and Technical Information of China (English)

    张凯; 刘春时; 李焱; 谢志坤; 王跃武

    2011-01-01

    HMS125p型四轴联动精密卧式加工中心是某公司在现有产品的基础上自主研发的一款大型四轴联动精密卧式加工中心机床.该机床具有高精度、高速度、高刚性、大扭矩等特点,是箱体、壳体等零部件高精、高效加工的理想设备,广泛适用于国防军工、汽车、造船、模具、通用机械等行业.介绍了该机床的主要机械结构特点和技术性能,并对机床整机进行了有限元分析,找出影响机床整机性能的薄弱环节,提出结构设计修改方向,从而使机床具有更好的性能.%HMS125p 4-axis linkage high-accuracy horizontal machining center is designed based on the existing products of some company. This machine which hss" the charaeteristics of high accuracy, high speed, high rigidity and high torque, is a ideal facility for high accuracy and high efficiency machining for box-shaped and shell-shaped parts, and is applied widely in national defence, war industry, automobile, shipment, die and universal mechanical industry etc. The main mechanical characteristics and technical data of the machine were introduced. The FEM analysis to the whale machine was made. The weakest parts that impacted the characteris-tics of the total machine were found. The direction for modification of the structure was presented to make the machine have better characteristics.

  12. Analysis and Design of a High-Stability,High-Accuracy,Low-Dropout Voltage Regulator%一种高稳定性高精度低压差线性稳压器的分析与设计

    Institute of Scientific and Technical Information of China (English)

    沈良国; 严祖树; 王钊; 张兴; 赵元富

    2007-01-01

    A high-accuracy,low-dropout (LDO) voltage regulator is presented.Using the slow-rolloff frequency compensation scheme,the LDO effectively overcomes the stability problem,facilitates the use of a ceramic capacitor,and improves the output voltage accuracy,which is critical for powering high-performance analog circuitry.The slow-rolloff compensation scheme is realized by introducing three pole-zero pairs,including the proposed pole-zero pair and sense zero.The post-layout simulation results demonstrate that this LDO has robust system stability,a high open-loop gain,and a high unit-gain frequency,which lead to excellent regulation and transient response performance.The line and load regulation are 27μV/V and 3.78μV/mA,and the overshoots of the output voltage are less than 30mV,while the dropout voltage is 120mV for a 150mA load current.%提出了LDO,其基于缓慢滚降式频率补偿方法,通过在电路中引入三个极零对(极零对的产生没有增加静态功耗),不仅克服了常规LDO不能使用低等效串联电阻、低成本陶瓷输出电容的缺点,而且确保了系统在整个负载和输入电压变化范围内稳定工作.由于LDO通常给高性能模拟电路供电,因此其输出电压精度至关重要;而该补偿方法能满足高环路增益、高单位增益带宽的设计要求,从而大幅提高LDO的精度.该LDO基于0.5μm CMOS工艺实现.后仿结果表明,即使在低压满负载条件下,其开环DC增益仍高于70dB,满载时单位增益带宽可达3MHz,线性调整率和负载调整率分别为27μV/V和3.78μV/mA,过冲和欠冲电压均小于30mV,负载电流为150mA时的漏失电压(dropout电压)仅为120mV.

  13. Liquid chromatography-high resolution/ high accuracy (tandem) mass spectrometry-based identification of in vivo generated metabolites of the selective androgen receptor modulator ACP-105 for doping control purposes.

    Science.gov (United States)

    Thevis, Mario; Thomas, Andreas; Piper, Thomas; Krug, Oliver; Delahaut, Philippe; Schänzer, Wilhelm

    2014-01-01

    Selective androgen receptor modulators (SARMs) represent an emerging class of therapeutics which have been prohibited in sport as anabolic agents according to the regulations of the World Anti-Doping Agency (WADA) since 2008. Within the past three years, numerous adverse analytical findings with SARMs in routine doping control samples have been reported despite missing clinical approval of these substances. Hence, preventive doping research concerning the metabolism and elimination of new therapeutic entities of the class of SARMs are vital for efficient and timely sports drug testing programs as banned compounds are most efficiently screened when viable targets (for example, characteristic metabolites) are identified. In the present study, the metabolism of ACP-105, a novel SARM drug candidate, was studied in vivo in rats. Following oral administration, urine samples were collected over a period of seven days and analyzed for metabolic products by Liquid chromatography-high resolution/high accuracy (tandem) mass spectrometry. Samples were subjected to enzymatic hydrolysis prior to liquid-liquid extraction and a total of seven major phase-I metabolites were detected, three of which were attributed to monohydroxylated and four to bishydroxylated ACP-105. The hydroxylation sites were assigned by means of diagnostic product ions and respective dissociation pathways of the analytes following positive or negative ionization and collisional activation as well as selective chemical derivatization. The identified metabolites were used as target compounds to investigate their traceability in a rat elimination urine samples study and monohydroxylated and bishydroxylated species were detectable for up to four and six days post-administration, respectively.

  14. Reconceptualizing metacomprehension calibration accuracy

    OpenAIRE

    Egan, Rylan Graham

    2012-01-01

    Accurate judgment of text comprehension is compulsory for learners to effectively self-regulate learning from text. Unfortunately, until relatively recently the literature on text comprehension judgment, termed metacomprehension, has shown learners to be inaccurate in their judgments. Over the last decade researchers have discovered that when learners use delayed summaries of text to make judgments metacomprehension accuracy increases. In contrast, when learners use individual differences (e....

  15. Assessing the Accuracy of High Resolution Digital Surface Models Computed by PhotoScan® and MicMac® in Sub-Optimal Survey Conditions

    Directory of Open Access Journals (Sweden)

    Marion Jaud

    2016-06-01

    Full Text Available For monitoring purposes and in the context of geomorphological research, Unmanned Aerial Vehicles (UAV appear to be a promising solution to provide multi-temporal Digital Surface Models (DSMs and orthophotographs. There are a variety of photogrammetric software tools available for UAV-based data. The objective of this study is to investigate the level of accuracy that can be achieved using two of these software tools: Agisoft PhotoScan® Pro and an open-source alternative, IGN© MicMac®, in sub-optimal survey conditions (rugged terrain, with a large variety of morphological features covering a range of roughness sizes, poor GPS reception. A set of UAV images has been taken by a hexacopter drone above the Rivière des Remparts, a river on Reunion Island. This site was chosen for its challenging survey conditions: the topography of the study area (i involved constraints on the flight plan; (ii implied errors on some GPS measurements; (iii prevented an optimal distribution of the Ground Control Points (GCPs and; (iv was very complex to reconstruct. Several image processing tests are performed with different scenarios in order to analyze the sensitivity of each software package to different parameters (image quality, numbers of GCPs, etc.. When computing the horizontal and vertical errors within a control region on a set of ground reference targets, both methods provide rather similar results. A precision up to 3–4 cm is achievable with these software packages. The DSM quality is also assessed over the entire study area comparing PhotoScan DSM and MicMac DSM with a Terrestrial Laser Scanner (TLS point cloud. PhotoScan and MicMac DSM are also compared at the scale of particular features. Both software packages provide satisfying results: PhotoScan is more straightforward to use but its source code is not open; MicMac is recommended for experimented users as it is more flexible.

  16. Towards Understanding Spontaneous Speech Word Accuracy vs. Concept Accuracy

    CERN Document Server

    Boros, M; Gallwitz, F; Goerz, G; Hanrieder, G; Niemann, H

    1996-01-01

    In this paper we describe an approach to automatic evaluation of both the speech recognition and understanding capabilities of a spoken dialogue system for train time table information. We use word accuracy for recognition and concept accuracy for understanding performance judgement. Both measures are calculated by comparing these modules' output with a correct reference answer. We report evaluation results for a spontaneous speech corpus with about 10000 utterances. We observed a nearly linear relationship between word accuracy and concept accuracy.

  17. High-accuracy 233U(n, f ) cross-section measurement at the white-neutron source n TOF from near-thermal to 1 MeV neutron energy

    OpenAIRE

    Sarchiapone, L.; Savvidis, I.; Konovalov, V; Stephan, C.; Tagliente, G.; Krticka, M; Rudolf, G.; Kossionides, E.; Rullhusen, P; Leeb, H.; Salgado, J.; Capote, R.; Cano-Ott, D.; Mengoni, A.; Calviño Tavares, Francisco

    2009-01-01

    The 233U(n,f ) cross section has been measured at the white neutron source n TOF in a wide energy range with a dedicated fission ionization chamber. We report here the results from ∼30 meV to 1 MeV neutron energy. The 233U(n,f ) cross section has been determined relative to a reference sample of 235U(n,f )measured simultaneously with the same detector. The very high instantaneous neutron flux and the intrinsically low background of the n TOF installation result in an accuracy arou...

  18. Feasibility of high resolution seismic reflection to improve accuracy of hydrogeologic models in a culturally noisy part of Ventura County, CA, USA

    Science.gov (United States)

    Miller, R.; Black, W.; Miele, M.; Morgan, T.; Ivanov, J.; Xia, J.; Peterie, S.

    2011-01-01

    A high-resolution seismic reflection investigation mapped reflectors and identified characteristics potentially influencing the interpretation of the hydrogeology underlying a portion of the Oxnard Plain in Ventura County, California. Design and implementation of this study was heavily influenced by high levels of cultural noise from vehicles, power lines, roads, manufacturing facilities, and underground utilities/vaults. Acquisition and processing flows were tailored to this noisy environment and relatively shallow target interval. Layering within both upper and lower aquifer systems was delineated at a vertical resolution potential of around 2.5 m at 350 m depth. ?? 2011 Society of Exploration Geophysicists.

  19. On the accuracy of van der Waals inclusive density-functional theory exchange-correlation functionals for ice at ambient and high pressures

    Science.gov (United States)

    Santra, Biswajit; Klimeš, Jiří; Tkatchenko, Alexandre; Alfè, Dario; Slater, Ben; Michaelides, Angelos; Car, Roberto; Scheffler, Matthias

    2013-10-01

    Density-functional theory (DFT) has been widely used to study water and ice for at least 20 years. However, the reliability of different DFT exchange-correlation (xc) functionals for water remains a matter of considerable debate. This is particularly true in light of the recent development of DFT based methods that account for van der Waals (vdW) dispersion forces. Here, we report a detailed study with several xc functionals (semi-local, hybrid, and vdW inclusive approaches) on ice Ih and six proton ordered phases of ice. Consistent with our previous study [B. Santra, J. Klimeš, D. Alfè, A. Tkatchenko, B. Slater, A. Michaelides, R. Car, and M. Scheffler, Phys. Rev. Lett. 107, 185701 (2011)] which showed that vdW forces become increasingly important at high pressures, we find here that all vdW inclusive methods considered improve the relative energies and transition pressures of the high-pressure ice phases compared to those obtained with semi-local or hybrid xc functionals. However, we also find that significant discrepancies between experiment and the vdW inclusive approaches remain in the cohesive properties of the various phases, causing certain phases to be absent from the phase diagram. Therefore, room for improvement in the description of water at ambient and high pressures remains and we suggest that because of the stern test the high pressure ice phases pose they should be used in future benchmark studies of simulation methods for water.

  20. Accuracy of tablet splitting.

    Science.gov (United States)

    McDevitt, J T; Gurst, A H; Chen, Y

    1998-01-01

    We attempted to determine the accuracy of manually splitting hydrochlorothiazide tablets. Ninety-four healthy volunteers each split ten 25-mg hydrochlorothiazide tablets, which were then weighed using an analytical balance. Demographics, grip and pinch strength, digit circumference, and tablet-splitting experience were documented. Subjects were also surveyed regarding their willingness to pay a premium for commercially available, lower-dose tablets. Of 1752 manually split tablet portions, 41.3% deviated from ideal weight by more than 10% and 12.4% deviated by more than 20%. Gender, age, education, and tablet-splitting experience were not predictive of variability. Most subjects (96.8%) stated a preference for commercially produced, lower-dose tablets, and 77.2% were willing to pay more for them. For drugs with steep dose-response curves or narrow therapeutic windows, the differences we recorded could be clinically relevant.